Microinstabilities in weak density gradient tokamak systems

International Nuclear Information System (INIS)

Tang, W.M.; Rewoldt, G.; Chen, L.

1986-04-01

A prominent characteristic of auxiliary-heated tokamak discharges which exhibit improved (''H-mode type'') confinement properties is that their density profiles tend to be much flatter over most of the plasma radius. Depsite this favorable trend, it is emphasized here that, even in the limit of zero density gradient, low-frequency microinstabilities can persist due to the nonzero temperature gradient

Effect of magnetic configuration on density fluctuation and particle transport in LHD

International Nuclear Information System (INIS)

Tanaka, K.; Michael, C.; Yamagishi, O.; Ida, K.; Yamada, H.; Yoshinuma, M.; Yokoyama, M.; Miyazawa, J.; Morita, S.; Kawahata, K.; Tokzawa, T.; Shoji, M.; Vyacheslavov, L.N.; Sanin, A.L.

2005-01-01

The study of fluctuations and particle transport is important issue in heliotron and stellarator devices as well as in tokamaks. A two dimensional phase contrast interferometer (2D PCI) was developed to investigate fluctuation characteristics, which play role in confinement. The current 2D PCI can detect fluctuations for which -1 0.3 -1 and 5< f<500kHz. With the use of magnetic shear and the 2D detector, the spatial resolution around 20% of averaged minor radius is possible presently. The strongest fluctuations are localized in the plasma edge, where density gradients are negative, but fluctuations also exist in the positive density gradient region of the hollow density profile. The phase velocity of fluctuations in the positive gradient region is close to plasma ErxBt rotation. On the other hand, fluctuations in the negative density gradient region propagate in the ion diamagnetic direction in the plasma frame and do not follow ErxBt rotation. This suggests there is a different nature of the fluctuations in the positive and negative density gradient regions. A particle transport was studied by means of density modulation experiments. The systematic study was done at Rax=3.6m, which is so-called standard configuration. The density profiles vary from peaked to hollow with increasing heating power. It was also found that particle diffusion and convection are functions of electron temperature and its gradient respectively. The magnetic configuration is another parameter, which characterizes particle confinement. At more outward shifted configurations, helical ripple becomes larger and the ergodic region becomes thicker, then neoclassical transport becomes larger. However estimated diffusion coefficients are still around one order of magnitude larger than neoclassical values in edge region, where ρ = 0.7 ∼ 1.0 and they are larger at more outward configurations. At the same time the convection velocity is found to be comparable with neoclassical prediction at Rax=3

The effect of density gradients on hydrometers

Science.gov (United States)

Heinonen, Martti; Sillanpää, Sampo

2003-05-01

Hydrometers are simple but effective instruments for measuring the density of liquids. In this work, we studied the effect of non-uniform density of liquid on a hydrometer reading. The effect induced by vertical temperature gradients was investigated theoretically and experimentally. A method for compensating for the effect mathematically was developed and tested with experimental data obtained with the MIKES hydrometer calibration system. In the tests, the method was found reliable. However, the reliability depends on the available information on the hydrometer dimensions and density gradients.

Properties of ion temperature gradient and trapped electron modes in tokamak plasmas with inverted density profiles

Science.gov (United States)

Du, Huarong; Jhang, Hogun; Hahm, T. S.; Dong, J. Q.; Wang, Z. X.

2017-12-01

We perform a numerical study of linear stability of the ion temperature gradient (ITG) mode and the trapped electron mode (TEM) in tokamak plasmas with inverted density profiles. A local gyrokinetic integral equation is applied for this study. From comprehensive parametric scans, we obtain stability diagrams for ITG modes and TEMs in terms of density and temperature gradient scale lengths. The results show that, for the inverted density profile, there exists a normalized threshold temperature gradient above which the ITG mode and the TEM are either separately or simultaneously unstable. The instability threshold of the TEM for the inverted density profile is substantially different from that for normal and flat density profiles. In addition, deviations are found on the ITG threshold from an early analytic theory in sheared slab geometry with the adiabatic electron response [T. S. Hahm and W. M. Tang, Phys. Fluids B 1, 1185 (1989)]. A possible implication of this work on particle transport in pellet fueled tokamak plasmas is discussed.

Experimental study of particle transport and density fluctuation in LHD

International Nuclear Information System (INIS)

Tanaka, K.; Morita, S.; Sanin, A.; Michael, C.; Kawahata, K.; Yamada, H.; Miyazawa, J.; Tokuzawa, T.; Akiyama, T.; Goto, M.; Ida, K.; Yoshinuma, M.; Narihara, K.; Yamada, I.; Yokoyama, M.; Masuzaki, S.; Morisaki, T.; Sakamoto, R.; Funaba, H.; Komori, A.; Vyacheslavov, L.N.; Murakami, S.; Wakasa, A.

2005-01-01

A variety of electron density (n e ) profiles have been observed in Large Helical Device (LHD). The density profiles change dramatically with heating power and toroidal magnetic field (B t ) under the same line averaged density. The particle transport coefficients, i.e., diffusion coefficient (D) and convection velocity (V) are experimentally obtained from density modulation experiments in the standard configuration. The values of D and V are estimated separately at the core and edge. The diffusion coefficients are strong function of electron temperature (T e ) and are proportional to T e 1.7±0.9 in core and T e 1.1±0.14 in edge. And edge diffusion coefficients are proportional to B t -2.08 . It is found that the scaling of D in edge is close to gyro-Bohm-like in nature. The existence of non-zero V is observed. It is observed that the electron temperature (T e ) gradient can drive particle convection. This is particularly clear in the core region. The convection velocity in the core region reverses direction from inward to outward as the T e gradient increases. In the edge, the convection is inward directed in the most of the case of the present data set. And it shows modest tendency, whose value is proportional to T e gradient keeping inward direction. However, the toroidal magnetic field also significantly affects value and direction of V. The spectrum of density fluctuation changes at different heating power suggesting that it has an influence on particle transport. The peak wavenumber is around 0.1 times the inversed ion Larmor radius, as is expected from gyro-Bohm diffusion. The peaks of fluctuation intensity are localized at the plasma edge, where density gradient becomes negative and diffusion contributes most to the particle flux. These results suggest a qualitative correlation of fluctuations with particle diffusion. (author)

A density gradient theory based method for surface tension calculations

DEFF Research Database (Denmark)

Liang, Xiaodong; Michelsen, Michael Locht; Kontogeorgis, Georgios

2016-01-01

The density gradient theory has been becoming a widely used framework for calculating surface tension, within which the same equation of state is used for the interface and bulk phases, because it is a theoretically sound, consistent and computationally affordable approach. Based on the observation...... that the optimal density path from the geometric mean density gradient theory passes the saddle point of the tangent plane distance to the bulk phases, we propose to estimate surface tension with an approximate density path profile that goes through this saddle point. The linear density gradient theory, which...... assumes linearly distributed densities between the two bulk phases, has also been investigated. Numerical problems do not occur with these density path profiles. These two approximation methods together with the full density gradient theory have been used to calculate the surface tension of various...

Density gradients in ceramic pellets measured by computed tomography

International Nuclear Information System (INIS)

Sawicka, B.D.; Palmer, B.J.F.

1986-07-01

Density gradients are of fundamental importance in ceramic processing and computed tomography (CT) can provide accurate measurements of density profiles in sintered and unsintered ceramic parts. As a demonstration of this potential, the density gradients in an unsintered pellet pressed from an alumina powder were measured by CT scanning. To detect such small density gradients, the CT images must have good density resolution and be free from beam-hardening effects. This was achieved by measuring high-contrast (low-noise) images with the use of an Ir-192 isotopic source. A beam-hardening correction was applied. The resulting images are discussed relative to the transmission of forces through the powder mass during the pelletizing process

Self-similar solutions for multi-species plasma mixing by gradient driven transport

Science.gov (United States)

Vold, E.; Kagan, G.; Simakov, A. N.; Molvig, K.; Yin, L.

2018-05-01

Multi-species transport of plasma ions across an initial interface between DT and CH is shown to exhibit self-similar species density profiles under 1D isobaric conditions. Results using transport theory from recent studies and using a Maxwell–Stephan multi-species approximation are found to be in good agreement for the self-similar mix profiles of the four ions under isothermal and isobaric conditions. The individual ion species mass flux and molar flux profile results through the mixing layer are examined using transport theory. The sum over species mass flux is confirmed to be zero as required, and the sum over species molar flux is related to a local velocity divergence needed to maintain pressure equilibrium during the transport process. The light ion species mass fluxes are dominated by the diagonal coefficients of the diffusion transport matrix, while for the heaviest ion species (C in this case), the ion flux with only the diagonal term is reduced by about a factor two from that using the full diffusion matrix, implying the heavy species moves more by frictional collisions with the lighter species than by its own gradient force. Temperature gradient forces were examined by comparing profile results with and without imposing constant temperature gradients chosen to be of realistic magnitude for ICF experimental conditions at a fuel-capsule interface (10 μm scale length or greater). The temperature gradients clearly modify the relative concentrations of the ions, for example near the fuel center, however the mixing across the fuel-capsule interface appears to be minimally influenced by the temperature gradient forces within the expected compression and burn time. Discussion considers the application of the self-similar profiles to specific conditions in ICF.

Role of Density Gradient Driven Trapped Electron Modes in the H-Mode Inner Core with Electron Heating

Science.gov (United States)

Ernst, D.

2015-11-01

We present new experiments and nonlinear gyrokinetic simulations showing that density gradient driven TEM (DGTEM) turbulence dominates the inner core of H-Mode plasmas during strong electron heating. Thus α-heating may degrade inner core confinement in H-Mode plasmas with moderate density peaking. These DIII-D low torque quiescent H-mode experiments were designed to study DGTEM turbulence. Gyrokinetic simulations using GYRO (and GENE) closely match not only particle, energy, and momentum fluxes, but also density fluctuation spectra, with and without ECH. Adding 3.4 MW ECH doubles Te /Ti from 0.5 to 1.0, which halves the linear TEM critical density gradient, locally flattening the density profile. Density fluctuations from Doppler backscattering (DBS) intensify near ρ = 0.3 during ECH, displaying a band of coherent fluctuations with adjacent toroidal mode numbers. GYRO closely reproduces the DBS spectrum and its change in shape and intensity with ECH, identifying these as coherent TEMs. Prior to ECH, parallel flow shear lowers the effective nonlinear DGTEM critical density gradient 50%, but is negligible during ECH, when transport displays extreme stiffness in the density gradient. GS2 predictions show the DGTEM can be suppressed, to avoid degradation with electron heating, by broadening the current density profile to attain q0 >qmin > 1 . A related experiment in the same regime varied the electron temperature gradient in the outer half-radius (ρ ~ 0 . 65) using ECH, revealing spatially coherent 2D mode structures in the Te fluctuations measured by ECE imaging. Fourier analysis with modulated ECH finds a threshold in Te profile stiffness. Supported by the US DOE under DE-FC02-08ER54966 and DE-FC02-04ER54698.

Virus purification by CsCl density gradient using general centrifugation.

Science.gov (United States)

Nasukawa, Tadahiro; Uchiyama, Jumpei; Taharaguchi, Satoshi; Ota, Sumire; Ujihara, Takako; Matsuzaki, Shigenobu; Murakami, Hironobu; Mizukami, Keijirou; Sakaguchi, Masahiro

2017-11-01

Virus purification by cesium chloride (CsCl) density gradient, which generally requires an expensive ultracentrifuge, is an essential technique in virology. Here, we optimized virus purification by CsCl density gradient using general centrifugation (40,000 × g, 2 h, 4 °C), which showed almost the same purification ability as conventional CsCl density gradient ultracentrifugation (100,000 × g, 1 h, 4 °C) using phages S13' and φEF24C. Moreover, adenovirus strain JM1/1 was also successfully purified by this method. We suggest that general centrifugation can become a less costly alternative to ultracentrifugation for virus purification by CsCl densiy gradient and will thus encourage research in virology.

Transport in Halobacterium Halobium: Light-Induced Cation-Gradients, Amino Acid Transport Kinetics, and Properties of Transport Carriers

Science.gov (United States)

Lanyi, Janos K.

1977-01-01

Cell envelope vesicles prepared from H. halobium contain bacteriorhodopsin and upon illumination protons are ejected. Coupled to the proton motive force is the efflux of Na(+). Measurements of Na-22 flux, exterior pH change, and membrane potential, Delta(psi) (with the dye 3,3'-dipentyloxadicarbocyanine) indicate that the means of Na(+) transport is sodium/proton exchange. The kinetics of the pH changes and other evidence suggests that the antiport is electrogenic (H(+)/Na(++ greater than 1). The resulting large chemical gradient for Na(+) (outside much greater than inside), as well as the membrane potential, will drive the transport of 18 amino acids. The I9th, glutamate, is unique in that its accumulation is indifferent to Delta(psi): this amino acid is transported only when a chemical gradient for Na(+) is present. Thus, when more and more NaCl is included in the vesicles glutamate transport proceeds with longer and longer lags. After illumination the gradient of H+() collapses within 1 min, while the large Na(+) gradient and glutamate transporting activity persists for 10- 15 min, indicating that proton motive force is not necessary for transport. A chemical gradient of Na(+), arranged by suspending vesicles loaded with KCl in NaCl, drives glutamate transport in the dark without other sources of energy, with V(sub max) and K(sub m) comparable to light-induced transport. These and other lines of evidence suggest that the transport of glutamate is facilitated by symport with Na(+), in an electrically neutral fashion, so that only the chemical component of the Na(+) gradient is a driving force.

Analytic solutions for Rayleigh-Taylor growth rates in smooth density gradients

International Nuclear Information System (INIS)

Munro, D.H.

1988-01-01

The growth rate of perturbations on the shell of a laser fusion target can be estimated as √gk , where g is the shell acceleration and k is the transverse wave number of the perturbation. This formula overestimates the growth rate, and should be modified for the effects of density gradients and/or ablation of the unstable interface. The density-gradient effect is explored here analytically. With the use of variational calculus to explore all possible density profiles, the growth rate is shown to exceed √gk/(1+kL) , where L is a typical density-gradient scale length. Density profiles actually exhibiting this minimum growth rate are found

Probability density function method for variable-density pressure-gradient-driven turbulence and mixing

International Nuclear Information System (INIS)

Bakosi, Jozsef; Ristorcelli, Raymond J.

2010-01-01

Probability density function (PDF) methods are extended to variable-density pressure-gradient-driven turbulence. We apply the new method to compute the joint PDF of density and velocity in a non-premixed binary mixture of different-density molecularly mixing fluids under gravity. The full time-evolution of the joint PDF is captured in the highly non-equilibrium flow: starting from a quiescent state, transitioning to fully developed turbulence and finally dissipated by molecular diffusion. High-Atwood-number effects (as distinguished from the Boussinesq case) are accounted for: both hydrodynamic turbulence and material mixing are treated at arbitrary density ratios, with the specific volume, mass flux and all their correlations in closed form. An extension of the generalized Langevin model, originally developed for the Lagrangian fluid particle velocity in constant-density shear-driven turbulence, is constructed for variable-density pressure-gradient-driven flows. The persistent small-scale anisotropy, a fundamentally 'non-Kolmogorovian' feature of flows under external acceleration forces, is captured by a tensorial diffusion term based on the external body force. The material mixing model for the fluid density, an active scalar, is developed based on the beta distribution. The beta-PDF is shown to be capable of capturing the mixing asymmetry and that it can accurately represent the density through transition, in fully developed turbulence and in the decay process. The joint model for hydrodynamics and active material mixing yields a time-accurate evolution of the turbulent kinetic energy and Reynolds stress anisotropy without resorting to gradient diffusion hypotheses, and represents the mixing state by the density PDF itself, eliminating the need for dubious mixing measures. Direct numerical simulations of the homogeneous Rayleigh-Taylor instability are used for model validation.

Free water transport, small pore transport and the osmotic pressure gradient

NARCIS (Netherlands)

Parikova, Alena; Smit, Watske; Zweers, Machteld M.; Struijk, Dirk G.; Krediet, Raymond T.

2008-01-01

BACKGROUND: Water transport in peritoneal dialysis (PD) patients occurs through the small pores and water channels, the latter allowing free water transport (FWT). The osmotic gradient is known to be one of the major determinants of water transport. The objective of the study was to analyse the

Is the temperature gradient or the derivative of the density gradient responsible for drift solitons?

International Nuclear Information System (INIS)

Salat, A.

1990-01-01

In conventional drift wave theory the density gradient κ n =d lnn/dχ determines the linear phase velocity, and the (electron) temperature gradient κ T =d lnT/dχ gives rise to a nonlinear term which leads to the existence of soliton-type solutions and solitary waves. LAKHIN, MIKHAILOVSKI and ONISHCHENKO, Phys. Lett. A 119, 348 (1987) and Plasma Phys. and Contr. Fus. 30, 457 (1988), recently claimed that it is not κ T but essentially the derivative of the density gradient, dκ n /dχ, that is relevant. This claim is refuted by means of an expansion scheme in ε=eΦ/T≤1, where Φ is the drift wave potential. (orig.)

A self-consistent upward leader propagation model

International Nuclear Information System (INIS)

Becerra, Marley; Cooray, Vernon

2006-01-01

The knowledge of the initiation and propagation of an upward moving connecting leader in the presence of a downward moving lightning stepped leader is a must in the determination of the lateral attraction distance of a lightning flash by any grounded structure. Even though different models that simulate this phenomenon are available in the literature, they do not take into account the latest developments in the physics of leader discharges. The leader model proposed here simulates the advancement of positive upward leaders by appealing to the presently understood physics of that process. The model properly simulates the upward continuous progression of the positive connecting leaders from its inception to the final connection with the downward stepped leader (final jump). Thus, the main physical properties of upward leaders, namely the charge per unit length, the injected current, the channel gradient and the leader velocity are self-consistently obtained. The obtained results are compared with an altitude triggered lightning experiment and there is good agreement between the model predictions and the measured leader current and the experimentally inferred spatial and temporal location of the final jump. It is also found that the usual assumption of constant charge per unit length, based on laboratory experiments, is not valid for lightning upward connecting leaders

Depth perception: cuttlefish (Sepia officinalis) respond to visual texture density gradients.

Science.gov (United States)

Josef, Noam; Mann, Ofri; Sykes, António V; Fiorito, Graziano; Reis, João; Maccusker, Steven; Shashar, Nadav

2014-11-01

Studies concerning the perceptual processes of animals are not only interesting, but are fundamental to the understanding of other developments in information processing among non-humans. Carefully used visual illusions have been proven to be an informative tool for understanding visual perception. In this behavioral study, we demonstrate that cuttlefish are responsive to visual cues involving texture gradients. Specifically, 12 out of 14 animals avoided swimming over a solid surface with a gradient picture that to humans resembles an illusionary crevasse, while only 5 out of 14 avoided a non-illusionary texture. Since texture gradients are well-known cues for depth perception in vertebrates, we suggest that these cephalopods were responding to the depth illusion created by the texture density gradient. Density gradients and relative densities are key features in distance perception in vertebrates. Our results suggest that they are fundamental features of vision in general, appearing also in cephalopods.

Improved alternating gradient transport and focusing of neutral molecules

International Nuclear Information System (INIS)

Kalnins, Juris; Lambertson, Glen; Gould, Harvey

2001-01-01

Polar molecules, in strong-field seeking states, can be transported and focused by an alternating sequence of electric field gradients that focus in one transverse direction while defocusing in the other. We show by calculation and numerical simulation, how one may greatly improve the alternating gradient transport and focusing of molecules. We use a new optimized multipole lens design, a FODO lattice beam transport line, and lenses to match the beam transport line to the beam source and the final focus. We derive analytic expressions for the potentials, fields, and gradients that may be used to design these lenses. We describe a simple lens optimization procedure and derive the equations of motion for tracking molecules through a beam transport line. As an example, we model a straight beamline that transports a 560 m/s jet-source beam of methyl fluoride molecules 15 m from its source and focuses it to 2 mm diameter. We calculate the beam transport line acceptance and transmission, for a beam with velocity spread, and estimate the transmitted intensity for specified source conditions. Possible applications are discussed

Proton gradients and proton-dependent transport processes in the chloroplast

Directory of Open Access Journals (Sweden)

Ricarda eHöhner

2016-02-01

Full Text Available Proton gradients are fundamental to chloroplast function. Across thylakoid membranes, the light induced proton gradient is essential for ATP synthesis. As a result of proton pumping into the thylakoid lumen, an alkaline stromal pH develops, which is required for full activation of pH-dependent Calvin Benson cycle enzymes. This implies that a pH gradient between the cytosol (pH 7 and the stroma (pH 8 is established upon illumination. To maintain this pH gradient chloroplasts actively extrude protons. More than 30 years ago it was already established that these proton fluxes are electrically counterbalanced by Mg2+, K+ or Cl- fluxes, but only recently the first transport systems that regulate the pH gradient were identified. Notably several (Na+,K+/H+ antiporter systems where identified, that play a role in pH gradient regulation, ion homeostasis, osmoregulation, or coupling of secondary active transport. The established pH gradients are important to drive uptake of essential ions and solutes, but not many transporters involved have been identified to date. In this mini review we summarize the current status in the field and the open questions that need to be addressed in order to understand how pH gradients are maintained, how this is interconnected with other transport processes and what this means for chloroplast function.

Effect of Crustal Density Structures on GOCE Gravity Gradient Observables

Directory of Open Access Journals (Sweden)

Robert Tenzer Pavel Novák

2013-01-01

Full Text Available We investigate the gravity gradient components corrected for major known anomalous density structures within the Earth¡¦s crust. Heterogeneous mantle density structures are disregarded. The gravimetric forward modeling technique is utilized to compute the gravity gradients based on methods for a spherical harmonic analysis and synthesis of a gravity field. The Earth¡¦s gravity gradient components are generated using the global geopotential model GOCO-03s. The topographic and stripping gravity corrections due to the density contrasts of the ocean and ice are computed from the global topographic/bathymetric model DTM2006.0 (which also includes the ice-thickness dataset. The discrete data of sediments and crust layers taken from the CRUST2.0 global crustal model are then used to apply the additional stripping corrections for sediments and remaining anomalous crustal density structures. All computations are realized globally on a one arc-deg geographical grid at a mean satellite elevation of 255 km. The global map of the consolidated crust-stripped gravity gradients reveals distinctive features which are attributed to global tectonics, lithospheric plate configuration, lithosphere structure and mantle dynamics (e.g., glacial isostatic adjustment, mantle convection. The Moho signature, which is the most pronounced signal in these refined gravity gradients, is superimposed over a weaker gravity signal of the lithospheric mantle. An interpretational quality of the computed (refined gravity gradient components is mainly limited by a low accuracy and resolution of the CRUST2.0 sediment and crustal layer data and unmodeled mantle structures.

Semi-local machine-learned kinetic energy density functional with third-order gradients of electron density

Science.gov (United States)

Seino, Junji; Kageyama, Ryo; Fujinami, Mikito; Ikabata, Yasuhiro; Nakai, Hiromi

2018-06-01

A semi-local kinetic energy density functional (KEDF) was constructed based on machine learning (ML). The present scheme adopts electron densities and their gradients up to third-order as the explanatory variables for ML and the Kohn-Sham (KS) kinetic energy density as the response variable in atoms and molecules. Numerical assessments of the present scheme were performed in atomic and molecular systems, including first- and second-period elements. The results of 37 conventional KEDFs with explicit formulae were also compared with those of the ML KEDF with an implicit formula. The inclusion of the higher order gradients reduces the deviation of the total kinetic energies from the KS calculations in a stepwise manner. Furthermore, our scheme with the third-order gradient resulted in the closest kinetic energies to the KS calculations out of the presented functionals.

Numerical modeling of solute transport in a sand tank physical model under varying hydraulic gradient and hydrological stresses

Science.gov (United States)

Atlabachew, Abunu; Shu, Longcang; Wu, Peipeng; Zhang, Yongjie; Xu, Yang

2018-03-01

This laboratory study improves the understanding of the impacts of horizontal hydraulic gradient, artificial recharge, and groundwater pumping on solute transport through aquifers. Nine experiments and numerical simulations were carried out using a sand tank. The variable-density groundwater flow and sodium chloride transport were simulated using the three-dimensional numerical model SEAWAT. Numerical modelling results successfully reproduced heads and concentrations observed in the sand tank. A higher horizontal hydraulic gradient enhanced the migration of sodium chloride, particularly in the groundwater flow direction. The application of constant artificial recharge increased the spread of the sodium chloride plume in both the longitudinal and lateral directions. In addition, groundwater pumping accelerated spreading of the sodium chloride plume towards the pumping well. Both higher hydraulic gradient and pumping rate generated oval-shaped plumes in the horizontal plane. However, the artificial recharge process produced stretched plumes. These effects of artificial recharge and groundwater pumping were greater under higher hydraulic gradient. The concentration breakthrough curves indicated that emerging solutions never attained the concentration of the originally injected solution. This is probably because of sorption of sodium chloride onto the silica sand and/or the exchange of sodium chloride between the mobile and immobile liquid domains. The fingering and protruding plume shapes in the numerical models constitute instability zones produced by buoyancy-driven flow. Overall, the results have substantiated the influences of hydraulic gradient, boundary condition, artificial recharge, pumping rate and density differences on solute transport through a homogeneous unconfined aquifer. The implications of these findings are important for managing liquid wastes.

Relativistic self-focusing of ultra-high intensity X-ray laser beams in warm quantum plasma with upward density profile

International Nuclear Information System (INIS)

Habibi, M.; Ghamari, F.

2014-01-01

The results of a numerical study of high-intensity X-ray laser beam interaction with warm quantum plasma (WQP) are presented. By means of an upward ramp density profile combined with quantum factors specially the Fermi velocity, we have demonstrated significant relativistic self-focusing (RSF) of a Gaussian electromagnetic beam in the WQP where the Fermi temperature term in the dielectric function is important. For this purpose, we have considered the quantum hydrodynamics model that modifies refractive index of inhomogeneous WQPs with the inclusion of quantum correction through the quantum statistical and diffraction effects in the relativistic regime. Also, to better illustration of the physical difference between warm and cold quantum plasmas and their effect on the RSF, we have derived the envelope equation governing the spot size of X-ray laser beam in Q-plasmas. In addition to the upward ramp density profile, we have found that the quantum effects would be caused much higher oscillation and better focusing of X-ray laser beam in the WQP compared to that of cold quantum case. Our computational results reveal the importance of the use of electrons density profile and Fermi speed in enhancing self-focusing of laser beam

Destabilization of drift waves due to nonuniform density gradient

International Nuclear Information System (INIS)

Hirose, A.; Ishihara, O.

1985-01-01

It is shown that the conventional mode differential equation for low frequency electrostatic waves in a tokamak does not contain full ion dynamics. Both electrons and ions contribute to the ballooning term, which is subject to finite ion Larmor radius effects. Also, both fluid ion approximation and kinetic ion model yield the same correction. Reexamined are the density gradient universal mode and ion temperature gradient instability employing the lowest order Pearlstein-Berk type radial eigenfunctions. No unstable, bounded, energy outgoing eigenfunctions have been found. In particular, a large ion temperature gradient (eta/sub i/) tends to further stabilize the temperature gradient driven mode

Density limit and cross-field edge transport scaling in Alcator C-Mod

International Nuclear Information System (INIS)

LaBombard, B.

2002-01-01

Experiments in Alcator C-Mod have uncovered a direct link between the character and scaling of edge transport and the empirical Greenwald density limit (n G ). In low to moderate density discharges, the scrape-off layer (SOL) exhibits a two-layer structure: a near SOL (∼5 mm zone) with steep density and temperature gradients and a far SOL with flatter profiles. In the far SOL, the transport fluxes exhibit large transport events ('bursts' which carry particles to main-chamber structures. In the near SOL, transport fluxes appear to be less 'bursty' particle diffusivities in this region is found to increase strongly with local plasma collisionality. As n/n G (or collisionality) is raised, cross-field heat convection begins to compete with parallel conduction to the divertor. At N/n G ∼0.5, T E at the separatrix is reduced. As n/n G approaches ∼1, regions inside the separatrix exhibit flatter profiles with 'bursty' transport behavior; cross-field heat convection to main-chamber structures becomes comparable to the radiated power. Thus as n/n G is increased, cross-field edge transport physics progressively changes, ultimately impacting the power balance of the discharge near N/n G ∼1. (author)

OptiPrep? Density Gradient Solutions for Macromolecules and Macromolecular Complexes

Directory of Open Access Journals (Sweden)

John Graham

2002-01-01

Full Text Available Any density gradient for the isolation of mammalian cells should ideally only expose the sedimenting particles to an increasing concentration of the gradient solute. Thus they will experience only an increasing density and viscosity, other parameters such as osmolality, pH, ionic strength and the concentration of important additives (such as EDTA or divalent cations should remain as close to constant as possible. This Protocol Article describes the strategies for the dilution of OptiPrep™ in order to prepare such solutions for mammalian cells.

General approach for solving the density gradient theory in the interfacial tension calculations

DEFF Research Database (Denmark)

Liang, Xiaodong; Michelsen, Michael Locht

2017-01-01

Within the framework of the density gradient theory, the interfacial tension can be calculated by finding the density profiles that minimize an integral of two terms over the system of infinite width. It is found that the two integrands exhibit a constant difference along the interface for a finite...... property evaluations compared to other methods. The performance of the algorithm with recommended parameters is analyzed for various systems, and the efficiency is further compared with the geometric-mean density gradient theory, which only needs to solve nonlinear algebraic equations. The results show...... that the algorithm is only 5-10 times less efficient than solving the geometric-mean density gradient theory....

Nernst-Planck modeling of multicomponent ion transport in a Nafion membrane at high current density

NARCIS (Netherlands)

Moshtari Khah, S.; Oppers, N.A.W.; de Groot, M.T.; Keurentjes, J.T.F.; Schouten, J.C.; van der Schaaf, J.

A mathematical model of multicomponent ion transport through a cation-exchange membrane is developed based on the Nernst–Planck equation. A correlation for the non-linear potential gradient is derived from current density relation with fluxes. The boundary conditions are determined with the Donnan

Numerical Study on Density Gradient Carbon-Carbon Composite for Vertical Launching System

Science.gov (United States)

Yoon, Jin-Young; Kim, Chun-Gon; Lim, Juhwan

2018-04-01

This study presents new carbon-carbon (C/C) composite that has a density gradient within single material, and estimates its heat conduction performance by a numerical method. To address the high heat conduction of a high-density C/C, which can cause adhesion separation in the steel structures of vertical launching systems, density gradient carbon-carbon (DGCC) composite is proposed due to its exhibiting low thermal conductivity as well as excellent ablative resistance. DGCC is manufactured by hybridizing two different carbonization processes into a single carbon preform. One part exhibits a low density using phenolic resin carbonization to reduce heat conduction, and the other exhibits a high density using thermal gradient-chemical vapor infiltration for excellent ablative resistance. Numerical analysis for DGCC is performed with a heat conduction problem, and internal temperature distributions are estimated by the forward finite difference method. Material properties of the transition density layer, which is inevitably formed during DGCC manufacturing, are assumed to a combination of two density layers for numerical analysis. By comparing numerical results with experimental data, we validate that DGCC exhibits a low thermal conductivity, and it can serve as highly effective ablative material for vertical launching systems.

Pressure gradient turbulent transport and collisionless reconnection

International Nuclear Information System (INIS)

Connor, J.W.

1993-01-01

The scale invariance technique is employed to discuss pressure gradient driven turbulent transport when an Ohm's law with electron inertia, rather than resistivity, is relevant. An expression for thermal diffusivity which has many features appropriate to L-mode transport in tokamaks, is seen to have greater generality than indicated by their particular calculation. The results of applying the technique to a more appropriate collisionless Ohm's law are discussed. (Author)

Solute transport with time-variable flow paths during upward and downward flux in a heterogeneous unsaturated porous medium

Science.gov (United States)

Cremer, Clemens; Neuweiler, Insa; Bechtold, Michel; Vanderborght, Jan

2014-05-01

To acquire knowledge of solute transport through the unsaturated zone in the shallow subsurface is decisive to assess groundwater quality, nutrient cycling or to plan remediation strategies. The shallow subsurface is characterized by structural heterogeneity and strongly influenced by atmospheric conditions. This leads to changing flow directions, strong temporal changes in saturation and heterogeneous water fluxes during infiltration and evaporation events. Recent studies (e.g. Lehmann and Or, 2009; Bechtold et al.,2011) demonstrated the importance of lateral flow and solute transport during evaporation conditions (upward flux). The heterogeneous structure in these studies was constructed using two types of sand with strong material contrasts and arranged in parallel with a vertical orientation. Lateral transport and redistribution of solute from coarse to fine media was observed deeper in the soil column and from fine to coarse close to the soil surface. However, if boundary conditions are reversed due to precipitation, the flow field is not necessarily reversed in the same manner, resulting in entirely different transport patterns for downward and upward flow. Therefore, considering net-flow rates alone is misleading when describing transport under those conditions. In this contribution we analyze transport of a solute in the shallow subsurface to assess effects resulting from the temporal change of heterogeneous soil structures due to dynamic flow conditions. Two-dimensional numerical simulations of unsaturated flow and transport are conducted using a coupled finite volume and random walk particle tracking algorithm to quantify solute transport and leaching rates. Following previous studies (Lehmann and Or, 2009; Bechtold et al., 2011), the chosen domain is composed of two materials, coarse and fine sand, arranged in parallel with a vertical orientation. Hence, one sharp interface of strong material heterogeneity is induced. During evaporation both sands are

A novel technique for real-time estimation of edge pedestal density gradients via reflectometer time delay data

Energy Technology Data Exchange (ETDEWEB)

Zeng, L., E-mail: zeng@fusion.gat.com; Doyle, E. J.; Rhodes, T. L.; Wang, G.; Sung, C.; Peebles, W. A. [Physics and Astronomy Department, University of California, Los Angeles, California 90095 (United States); Bobrek, M. [Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831-6006 (United States)

2016-11-15

A new model-based technique for fast estimation of the pedestal electron density gradient has been developed. The technique uses ordinary mode polarization profile reflectometer time delay data and does not require direct profile inversion. Because of its simple data processing, the technique can be readily implemented via a Field-Programmable Gate Array, so as to provide a real-time density gradient estimate, suitable for use in plasma control systems such as envisioned for ITER, and possibly for DIII-D and Experimental Advanced Superconducting Tokamak. The method is based on a simple edge plasma model with a linear pedestal density gradient and low scrape-off-layer density. By measuring reflectometer time delays for three adjacent frequencies, the pedestal density gradient can be estimated analytically via the new approach. Using existing DIII-D profile reflectometer data, the estimated density gradients obtained from the new technique are found to be in good agreement with the actual density gradients for a number of dynamic DIII-D plasma conditions.

Engineering zonal cartilage through bioprinting collagen type II hydrogel constructs with biomimetic chondrocyte density gradient.

Science.gov (United States)

Ren, Xiang; Wang, Fuyou; Chen, Cheng; Gong, Xiaoyuan; Yin, Li; Yang, Liu

2016-07-20

Cartilage tissue engineering is a promising approach for repairing and regenerating cartilage tissue. To date, attempts have been made to construct zonal cartilage that mimics the cartilaginous matrix in different zones. However, little attention has been paid to the chondrocyte density gradient within the articular cartilage. We hypothesized that the chondrocyte density gradient plays an important role in forming the zonal distribution of extracellular matrix (ECM). In this study, collagen type II hydrogel/chondrocyte constructs were fabricated using a bioprinter. Three groups were created according to the total cell seeding density in collagen type II pre-gel: Group A, 2 × 10(7) cells/mL; Group B, 1 × 10(7) cells/mL; and Group C, 0.5 × 10(7) cells/mL. Each group included two types of construct: one with a biomimetic chondrocyte density gradient and the other with a single cell density. The constructs were cultured in vitro and harvested at 0, 1, 2, and 3 weeks for cell viability testing, reverse-transcription quantitative PCR (RT-qPCR), biochemical assays, and histological analysis. We found that total ECM production was positively correlated with the total cell density in the early culture stage, that the cell density gradient distribution resulted in a gradient distribution of ECM, and that the chondrocytes' biosynthetic ability was affected by both the total cell density and the cell distribution pattern. Our results suggested that zonal engineered cartilage could be fabricated by bioprinting collagen type II hydrogel constructs with a biomimetic cell density gradient. Both the total cell density and the cell distribution pattern should be optimized to achieve synergistic biological effects.

The influence of the unsaturated zone on the upward transport of radionuclides in soils

International Nuclear Information System (INIS)

Elert, M.; Lindgren, M.

1993-07-01

The transport of radionuclides from the deep soil to the surface soil is an important part of biosphere modelling. In this study the effect of transient hydrological conditions on the upward transport of radionuclides through soils has been studied. The effect of varying soil properties, climate conditions have been considered as well as the effect of a fluctuating groundwater level. It was shown that the soil characteristics influences the radionuclide concentration; an increased hydraulic conductivity leads to increase in the concentration in the root zone. The climate conditions were shown to be of major importance. A dispersion dependent on both velocity and saturation leads to a more effective upward transport of radionuclides to the root zone than if dispersion is assumed to be dependent only on the saturation. The boundary condition used in the case with varying groundwater level may be more realistic than the boundary condition applied for the case with a constant groundwater level. All calculations with varying groundwater level gave lower radionuclide concentration in the root zone. Sorption is redox sensitive for many radionuclides and the redox potential in the soil will be affected by the degree of water saturation. The performed calculations did, however, not result in any significant change in the radionuclide concentration in the root zone due to variation in sorption. A comparison between the results of the two models show that the compartment model in all studied cases predicts a higher annual average radionuclide concentration in the root zone than the numerical model. Annual variation in soil water flow were not included in the compartment model. During the summer the concentration in the root zone may be several times higher than the annual average. This may be important for plant uptake, since this increased concentrations coincides with the plant growing season. The calculations made with the simple compartment model also show that these

Nonlinear theory of trapped electron temperature gradient driven turbulence in flat density H-mode plasmas

International Nuclear Information System (INIS)

Hahm, T.S.

1990-12-01

Ion temperature gradient turbulence based transport models have difficulties reconciling the recent DIII-D H-mode results where the density profile is flat, but χ e > χ i in the core region. In this work, a nonlinear theory is developed for recently discovered ion temperature gradient trapped electron modes propagating in the electron diamagnetic direction. This instability is predicted to be linearly unstable for L Ti /R approx-lt κ θ ρ s approx-lt (L Ti /R) 1/4 . They are also found to be strongly dispersive even at these long wavelengths, thereby suggesting the importance of the wave-particle-wave interactions in the nonlinear saturation phase. The fluctuation spectrum and anomalous fluxes are calculated. In accordance with the trends observed in DIII-D, the predicted electron thermal diffusivity can be larger than the ion thermal diffusivity. 17 refs., 3 figs

Method of online cleanliness control for upward-facing transport mirrors in integration test bed

International Nuclear Information System (INIS)

Zhao Longbiao; Qin Lang; Zhou Guorui; Ye Yayun; Zhang Chuanchao; Miao Xinxiang; Wang Hongbin; Yuan Xiaodong; Wang Xiaohong; Cheng Xiaofeng

2013-01-01

An online cleanliness control method based on the online monitoring system was developed for controlling the particle pollution and damage of upward-facing transport mirrors in the integration test bed. By building up gas knife system, the online cleanliness processing was effectively achieved for the particle pollution on the mirror surface. By using the gas screen, the cleanliness of the mirror surface was effectively online maintained. The image processing system was applied to assessing the effect of online cleanliness processing. The experimental results indicate that the particle pollution was reduced by the gas knife and the gas screen was useful to avoid the settlement of particle pollution. (authors)

An investigation on near wall transport characteristics in an adiabatic upward gas-liquid two-phase slug flow

Science.gov (United States)

Zheng, Donghong; Che, Defu

2007-08-01

The near-wall transport characteristics, inclusive of mass transfer coefficient and wall shear stress, which have a great effect on gas-liquid two-phase flow induced internal corrosion of low alloy pipelines in vertical upward oil and gas mixing transport, have been both mechanistically and experimentally investigated in this paper. Based on the analyses on the hydrodynamic characteristics of an upward slug unit, the mass transfer in the near wall can be divided into four zones, Taylor bubble nose zone, falling liquid film zone, Taylor bubble wake zone and the remaining liquid slug zone; the wall shear stress can be divided into two zones, the positive wall shear stress zone associated with the falling liquid film and the negative wall shear stress zone associated with the liquid slug. Based on the conventional mass transfer and wall shear stress characteristics formulas of single phase liquid full-pipe turbulent flow, corrected normalized mass transfer coefficient formula and wall shear stress formula are proposed. The calculated results are in good agreement with the experimental data. The shear stress and the mass transfer coefficient in the near wall zone are increased with the increase of superficial gas velocity and decreased with the increase of superficial liquid velocity. The mass transfer coefficients in the falling liquid film zone and the wake zone of leading Taylor bubble are lager than those in the Taylor bubble nose zone and the remaining liquid slug zone, and the wall shear stress associated falling liquid film is larger than that associated the liquid slug. The mass transfer coefficient is within 10-3 m/s, and the wall shear stress below 103 Pa. It can be concluded that the alternate wall shear stress due to upward gas-liquid slug flow is considered to be the major cause of the corrosion production film fatigue cracking.

Equatorial density depletions observed at 840 km during the great magnetic storm of March 1989

International Nuclear Information System (INIS)

Greenspan, M.E.; Rasmussen, C.E.; Burke, W.J.; Abdu, M.A.

1991-01-01

Early on March 14, 1989, a thermal plasma probe on the Defense Meteorological Satellite Program (DMSP) F9 spacecraft detected extensive and dramatic decreases in the ion density at 840 km, near 2130 LT, during two consecutive transequatorial passes over South America. The order of magnitude decreases in the ion density extended more than 4,000 km along the satellite track. The depletions were accompanied by upward and westward plasma drifts, both in excess of 100 m/s. Their onsets and terminations were marked by extremely sharp density gradients. A partial depletion was detected over the eastern Pacific during the following orbit. The DMSP F9 ground track passed slightly west of a Brazilian total electron content (TEC) station and two Brazilian ionosondes during the first depletion encounter. The TEC fell far below normal during the night of March 13-14. The ionosonde measurements indicate that, in the hour after sunset, before DMSP passed through the depletions, the F 2 layer rose rapidly and disappeared, but at the time of the first depletion encounter, h m F 2 was decreasing over one of the stations. The authors develop a phenomenological model reconciling DMSP F8, F9 and ground-based measurements. The calculations show that rapid upward drifts sustained for several hours can produce depletions in the equatorial ion density with sharp gradients at their high-latitude boundaries, consistent with the data. They discuss possible contributing mechanisms for generating these upward drifts. These include direct penetration of the magnetospheric electric field to low latitudes, the electric fields generated by the disturbance dynamo, and the effects of conductivity gradients near the dusk terminator and the South Atlantic anomaly

Transport due to ion pressure gradient turbulence

International Nuclear Information System (INIS)

Connor, J.W.

1986-01-01

Turbulent transport due to the ion pressure gradient (or temperature drift) instability is thought to be significant when etasub(i)=d(ln Tsub(i))/d(ln n)>1. The invariance properties of the governing equations under scale transformations are used to discuss the characteristics of this turbulence. This approach not only clarifies the relationships between earlier treatments but also, in certain limits, completely determines the scaling properties of the fluctuations and the consequent thermal transport. (author)

Graph approach to the gradient expansion of density functionals

International Nuclear Information System (INIS)

Kozlowski, P.M.; Nalewajski, R.F.

1986-01-01

A graph representation of terms in the gradient expansion of the kinetic energy density functional is presented. They briefly discuss the implications of the virial theorem for the graph structure and relations between possible graphs at a given order of expansion

Microfluidic Adaptation of Density-Gradient Centrifugation for Isolation of Particles and Cells

Directory of Open Access Journals (Sweden)

Yuxi Sun

2017-08-01

Full Text Available Density-gradient centrifugation is a label-free approach that has been extensively used for cell separations. Though elegant, this process is time-consuming (>30 min, subjects cells to high levels of stress (>350 g and relies on user skill to enable fractionation of cells that layer as a narrow band between the density-gradient medium and platelet-rich plasma. We hypothesized that microfluidic adaptation of this technique could transform this process into a rapid fractionation approach where samples are separated in a continuous fashion while being exposed to lower levels of stress (<100 g for shorter durations of time (<3 min. To demonstrate proof-of-concept, we designed a microfluidic density-gradient centrifugation device and constructed a setup to introduce samples and medium like Ficoll in a continuous, pump-less fashion where cells and particles can be exposed to centrifugal force and separated via different outlets. Proof-of-concept studies using binary mixtures of low-density polystyrene beads (1.02 g/cm3 and high-density silicon dioxide beads (2.2 g/cm3 with Ficoll–Paque (1.06 g/cm3 show that separation is indeed feasible with >99% separation efficiency suggesting that this approach can be further adapted for separation of cells.

Comparison of preconditioned generalized conjugate gradient methods to two-dimensional neutron and photon transport equation

International Nuclear Information System (INIS)

Chen, G.S.

1997-01-01

We apply and compare the preconditioned generalized conjugate gradient methods to solve the linear system equation that arises in the two-dimensional neutron and photon transport equation in this paper. Several subroutines are developed on the basis of preconditioned generalized conjugate gradient methods for time-independent, two-dimensional neutron and photon transport equation in the transport theory. These generalized conjugate gradient methods are used. TFQMR (transpose free quasi-minimal residual algorithm), CGS (conjuage gradient square algorithm), Bi-CGSTAB (bi-conjugate gradient stabilized algorithm) and QMRCGSTAB (quasi-minimal residual variant of bi-conjugate gradient stabilized algorithm). These sub-routines are connected to computer program DORT. Several problems are tested on a personal computer with Intel Pentium CPU. (author)

Gradient-based stochastic estimation of the density matrix

Science.gov (United States)

Wang, Zhentao; Chern, Gia-Wei; Batista, Cristian D.; Barros, Kipton

2018-03-01

Fast estimation of the single-particle density matrix is key to many applications in quantum chemistry and condensed matter physics. The best numerical methods leverage the fact that the density matrix elements f(H)ij decay rapidly with distance rij between orbitals. This decay is usually exponential. However, for the special case of metals at zero temperature, algebraic decay of the density matrix appears and poses a significant numerical challenge. We introduce a gradient-based probing method to estimate all local density matrix elements at a computational cost that scales linearly with system size. For zero-temperature metals, the stochastic error scales like S-(d+2)/2d, where d is the dimension and S is a prefactor to the computational cost. The convergence becomes exponential if the system is at finite temperature or is insulating.

Effects of density gradients and fluctuations at the plasma edge on ECEI measurements at ASDEX Upgrade

Science.gov (United States)

Vanovac, B.; Wolfrum, E.; Denk, S. S.; Mink, F.; Laggner, F. M.; Birkenmeier, G.; Willensdorfer, M.; Viezzer, E.; Hoelzl, M.; Freethy, S. J.; Dunne, M. G.; Lessig, A.; Luhmann, N. C., Jr.; the ASDEX Upgrade Team; the EUROfusion MST1 Team

2018-04-01

Electron cyclotron emission imaging (ECEI) provides measurements of electron temperature (T e ) and its fluctuations (δT e ). However, when measuring at the plasma edge, in the steep gradient region, radiation transport effects must be taken into account. It is shown that due to these effects, the scrape-off layer region is not accessible to the ECEI measurements in steady state conditions and that the signal is dominated by the shine-through emission. Transient effects, such as filaments, can change the radiation transport locally, but cannot be distinguished from the shine-through. Local density measurements are essential for the correct interpretation of the electron cyclotron emission, since the density fluctuations influence the temperature measurements at the plasma edge. As an example, a low frequency 8 kHz mode, which causes 10%-15% fluctuations in the signal level of the ECEI, is analysed. The same mode has been measured with the lithium beam emission spectroscopy density diagnostic, and is very well correlated in time with high frequency magnetic fluctuations. With radiation transport modelling of the electron cyclotron radiation in the ECEI geometry, it is shown that the density contributes significantly to the radiation temperature (T rad) and the experimental observations have shown the amplitude modulation in both density and temperature measurements. The poloidal velocity of the low frequency mode measured by the ECEI is 3 km s-1. The calculated velocity of the high frequency mode measured with the magnetic pick-up coils is about 25 km s-1. Velocities are compared with the E × B background flow velocity and possible explanations for the origin of the low frequency mode are discussed.

Interacting Eigenmodes of a plasma diode with a density gradient

International Nuclear Information System (INIS)

Loefgren, T.; Gunell, H.

1997-08-01

The formation of narrow high frequency electric field spikes in plasma density gradients is investigated using one-dimensional particle in cell simulations. It is found that the shape of the plasma density gradient is very important for the spike formation. The spike appears also in simulations with immobile ions showing that a coupling to the ion motion, as for example in wave interactions, is not necessary for the formation of HF spikes. However, the HF spike influences the ion motion, and ion waves are seen in the simulations. It has been found, in experiments and simulations, that the electron velocity distribution function deviates from the Maxwellian distribution. Dispersion relations are calculated using realistic distribution functions. The spike can be seen as a coupled system of two Eigenmodes of a plasma diode fed by the beam-plasma interaction. Based on a simplified fluid description of such Eigenmodes, explanations for the localization of the spike, spatially and in frequency, are given. The density amplitude is comparable with the DC density level close to the cathode. Space charge limits of waves in this region seem to determine the amplitude of the spike through the Poisson's equation

Semiautomated system for the production and analysis of sucrose density gradients

International Nuclear Information System (INIS)

Lange, C.S.; Liberman, D.F.

1974-01-01

A semiautomated system in DNA damage studies permitting considerable accuracy, speed, and reproducibility in the making and fractionation of sucrose density gradients is described. The system consists of a modified Beckman gradient forming device that makes six gradients simultaneously and delivers them into six 12.5 ml polyallomer centrifuge tubes in such a manner that new material is continuously added to the meniscus of the gradient. The gradients are fractionated three at a time and up to 100 fractions per gradient can be collected automatically directly into scintillation vials with a choice of drop counting or time mode with rinse and automatic addition of scintillation fluid to each vial. The system can process up to six gradients per hour but centrifugation time is usually the limiting factor. With neutral sucrose gradients, sharp, reproducible, monodisperse peaks containing up to 100 percent of the gradient radioactivity are usually obtained but a smaller monodisperse peak containing as little as 3.5 percent of the gradient radioactivity can be detected under conditions where some pairs of molecules might tangle or dimerize. The resolution and reproducibility of this system when used with neutral sucrose gradients is at least the equal if not superior to that commonly claimed for alkaline sucrose gradients. (U.S.)

Development of a nonlocal convective mixing scheme with varying upward mixing rates for use in air quality and chemical transport models.

Science.gov (United States)

Mihailović, Dragutin T; Alapaty, Kiran; Sakradzija, Mirjana

2008-06-01

Asymmetrical convective non-local scheme (CON) with varying upward mixing rates is developed for simulation of vertical turbulent mixing in the convective boundary layer in air quality and chemical transport models. The upward mixing rate form the surface layer is parameterized using the sensible heat flux and the friction and convective velocities. Upward mixing rates varying with height are scaled with an amount of turbulent kinetic energy in layer, while the downward mixing rates are derived from mass conservation. This scheme provides a less rapid mass transport out of surface layer into other layers than other asymmetrical convective mixing schemes. In this paper, we studied the performance of a nonlocal convective mixing scheme with varying upward mixing in the atmospheric boundary layer and its impact on the concentration of pollutants calculated with chemical and air-quality models. This scheme was additionally compared versus a local eddy-diffusivity scheme (KSC). Simulated concentrations of NO(2) and the nitrate wet deposition by the CON scheme are closer to the observations when compared to those obtained from using the KSC scheme. Concentrations calculated with the CON scheme are in general higher and closer to the observations than those obtained by the KSC scheme (of the order of 15-20%). Nitrate wet deposition calculated with the CON scheme are in general higher and closer to the observations than those obtained by the KSC scheme. To examine the performance of the scheme, simulated and measured concentrations of a pollutant (NO(2)) and nitrate wet deposition was compared for the year 2002. The comparison was made for the whole domain used in simulations performed by the chemical European Monitoring and Evaluation Programme Unified model (version UNI-ACID, rv2.0) where schemes were incorporated.

Theoretical transport analysis of density limit with radial electric field in helical plasmas

International Nuclear Information System (INIS)

Toda, S.; Itoh, K.

2010-11-01

The confinement property in helical toroidal plasmas is clarified. The analysis is performed by use of the one-dimensional transport equations with the effect of the radiative loss and the radial profile of the electric field. The analytical results in the edge region show the steep gradient in the electron temperature, which indicates the transport barrier formation. Because of the rapid increase of the radiative loss at the low electron temperature, the anomalous heat diffusivity is reduced near the edge. Next, the efficiency of the heating power input in the presence of the radiative loss is studied. The scaling of the critical density in helical devices is also derived. (author)

Simultaneous realization of high density edge transport barrier and improved L-mode on CHS

International Nuclear Information System (INIS)

Minami, Takashi; Okamura, Shoichi; Suzuki, Chihiro

2008-10-01

An edge transport barrier (ETB) formation and an improved L-mode (IL mode) have been simultaneously realized in high density region (n-bar e - 1.2x10 20 m -3 ) on Compact Helical System (CHS). When the ETB is formed during the IL mode, the density reduction in the edge region is suppressed by the barrier formation. As a result of the continuous increasing of the temperature by the IL mode, the stored energy during the combined mode increased up to the maximum stored energy (W p - 9.4 kJ) recorded in CHS experiments. The plasma pressure in the peripheral region increases up to three times larger than that of the L-mode, and the large edge plasma pressure gradient is formed accompanying the pedestal structure. That is caused by the anomalous transport reduction that is confirmed from the sharp drop of the density fluctuation in the edge region. The neutral particle reduction in the peripheral region and the metallic impurity accumulation in the core plasma are simultaneously observed during the high density ETB formation. (author)

Three gradients and the perception of flat and curved surfaces.

Science.gov (United States)

Cutting, J E; Millard, R T

1984-06-01

Researchers of visual perception have long been interested in the perceived slant of a surface and in the gradients that purportedly specify it. Slant is the angle between the line of sight and the tangent to the planar surface at any point, also called the surface normal. Gradients are the sources of information that grade, or change, with visual angle as one looks from one's feet upward to the horizon. The present article explores three gradients--perspective, compression, and density--and the phenomenal impression of flat and curved surfaces. The perspective gradient is measured at right angles to the axis of tilt at any point in the optic array; that is, when looking down a hallway at the tiles of a floor receding in the distance, perspective is measured by the x-axis width of each tile projected on the image plane orthogonal to the line of sight. The compression gradient is the ratio of y/x axis measures on the projected plane. The density gradient is measured by the number of tiles per unit solid visual angle. For flat surfaces and many others, perspective and compression gradients decrease with distance, and the density gradient increases. We discuss the manner in which these gradients change for various types of surfaces. Each gradient is founded on a different assumption about textures on the surfaces around us. In Experiment 1, viewers assessed the three-dimensional character of projections of flat and curved surfaces receding in the distance. They made pairwise judgments of preference and of dissimilarity among eight stimuli in each of four sets. The presence of each gradient was manipulated orthogonally such that each stimulus had zero, one, two, or three gradients appropriate for either a flat surface or a curved surface. Judgments were made were made for surfaces with both regularly shaped and irregularly shaped textures scattered on them. All viewer assessment were then scaled in one dimension. Multiple correlation and regression on the scale values

Patterned gradient surface for spontaneous droplet transportation and water collection: simulation and experiment

International Nuclear Information System (INIS)

Tan, Xianhua; Zhu, Yiying; Shi, Tielin; Tang, Zirong; Liao, Guanglan

2016-01-01

We demonstrate spontaneous droplet transportation and water collection on wedge-shaped gradient surfaces consisting of alternating hydrophilic and hydrophobic regions. Droplets on the surfaces are modeled and simulated to analyze the Gibbs free energy and free energy gradient distributions. Big half-apex angle and great wettability difference result in considerable free energy gradient, corresponding to large driving force for spontaneous droplet transportation, thus causing the droplets to move towards the open end of the wedge-shaped hydrophilic regions, where the Gibbs free energy is low. Gradient surfaces are then fabricated and tested. Filmwise condensation begins on the hydrophilic regions, forming wedge-shaped tracks for water collection. Dropwise condensation occurs on the hydrophobic regions, where the droplet size distribution and departure diameters are controlled by the width of the regions. Condensate water from both the hydrophilic and hydrophobic regions are collected directionally to the open end of the wedge-shaped hydrophilic regions, agreeing with the simulations. Directional droplet transport and controllable departure diameters make the branched gradient surfaces more efficient than smooth surfaces for water collection, which proves that gradient surfaces are potential in water collection, microfluidic devices, anti-fogging and self-cleaning. (paper)

Active water transport in unicellular algae: where, why, and how.

Science.gov (United States)

Raven, John A; Doblin, Martina A

2014-12-01

The occurrence of active water transport (net transport against a free energy gradient) in photosynthetic organisms has been debated for several decades. Here, active water transport is considered in terms of its roles, where it is found, and the mechanisms by which it could occur. First there is a brief consideration of the possibility of active water transport into plant xylem in the generation of root pressure and the refilling of embolized xylem elements, and from an unsaturated atmosphere into terrestrial organisms living in habitats with limited availability of liquid water. There is then a more detailed consideration of volume and osmotic regulation in wall-less freshwater unicells, and the possibility of generation of buoyancy in marine phytoplankton such as large-celled diatoms. Calculations show that active water transport is a plausible mechanism to assist cells in upwards vertical movements, requires less energy than synthesis of low-density organic solutes, and potentially on a par with excluding certain ions from the vacuole. © The Author 2014. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Electron-temperature-gradient-driven drift waves and anomalous electron energy transport

International Nuclear Information System (INIS)

Shukla, P.K.; Murtaza, G.; Weiland, J.

1990-01-01

By means of a kinetic description for ions and Braginskii's fluid model for electrons, three coupled nonlinear equations governing the dynamics of low-frequency short-wavelength electrostatic waves in the presence of equilibrium density temperature and magnetic-field gradients in a two-component magnetized plasma are derived. In the linear limit a dispersion relation that admits new instabilities of drift waves is presented. An estimate of the anomalous electron energy transport due to non-thermal drift waves is obtained by making use of the saturated wave potential, which is deduced from the mixing-length hypothesis. Stationary solutions of the nonlinear equations governing the interaction of linearly unstable drift waves are also presented. The relevance of this investigation to wave phenomena in space and laboratory plasmas is pointed out. (author)

Time-Varying Hydraulic Gradient Model of Paste-Like Tailings in Long-Distance Pipeline Transportation

Directory of Open Access Journals (Sweden)

Li Yang

2017-01-01

Full Text Available Paste-like tailings slurry (PTLS is always simplified as a Bingham plastic fluid, leading to excessive computational errors in the calculation of the hydraulic gradient. In the case of paste-like tailings in long-distance pipeline transportation, to explore a high-precision and reliable hydraulic gradient formula, the rheological behavior of paste-like tailings slurry was analyzed, a time-varying hydraulic gradient model was constructed, and a series of laboratory shear tests were conducted. The results indicate that the PTLS shows noticeable shear-thinning characteristics in constant shear tests; the calculated hydraulic gradient declined by about 56%, from 4.44 MPa·km−1 to 1.95 MPa·km−1 within 253 s, and remained constant for the next four hours during the pipeline transportation. Comparing with the balance hydraulic gradient obtained in a semi-industrial loop test, the computational errors of those calculated by using the time-varying hydraulic gradient model, Jinchuan formula, and Shanxi formula are 15%, 78%, and 130%, respectively. Therefore, our model is a feasible and high-precision solution for the calculation of the hydraulic gradient of paste-like tailings in long-distance pipeline transportation.

Linking Soil Physical Parameters Along a Density Gradient in a Loess-Soil Long-Term Experiment

DEFF Research Database (Denmark)

Eden, Marie; Møldrup, Per; Schjønning, Per

2012-01-01

It is important to understand the impact of texture and organic carbon (OC) on soil structure development. Only few studies investigated this for silt-dominated soils. In this study, soil physical properties were determined on samples from a controlled experiment (Static Fertilization Experiment...... hydraulic conductivity. The management resulted in a distinct gradient in OC. A bulk density gradient developed from differences in amount of clay not complexed with OC. This gradient in bulk density mainly affected content of pores larger than 3 [mu]m. The air-connected porosity measured by a pycnometer...

78 FR 18326 - Agency Information Collection Activities; Comment Request; Upward Bound and Upward Bound Math...

Science.gov (United States)

2013-03-26

...; Comment Request; Upward Bound and Upward Bound Math Science Annual Performance Report AGENCY: The Office... considered public records. Title of Collection: Upward Bound and Upward Bound Math Science Annual Performance...) and Upward Bound Math and Science (UBMS) Programs. The Department is requesting a new APR because of...

Species interactions slow warming-induced upward shifts of treelines on the Tibetan Plateau

Science.gov (United States)

Liang, Eryuan; Wang, Yafeng; Piao, Shilong; Lu, Xiaoming; Camarero, Jesús Julio; Zhu, Haifeng; Zhu, Liping; Ciais, Philippe; Peñuelas, Josep

2016-01-01

The alpine treeline is commonly regarded as being sensitive to climatic warming because regeneration and growth of trees at treeline generally are limited by low temperature. The alpine treelines of the Tibetan Plateau (TP) occur at the highest elevations (4,900 m above sea level) in the Northern Hemisphere. Ongoing climatic warming is expected to shift treelines upward. Studies of treeline dynamics at regional and local scales, however, have yielded conflicting results, indicating either unchanging treeline elevations or upward shifts. To reconcile this conflict, we reconstructed in detail a century of treeline structure and tree recruitment at sites along a climatic gradient of 4 °C and mean annual rainfall of 650 mm on the eastern TP. Species interactions interacted with effects of warming on treeline and could outweigh them. Densification of shrubs just above treeline inhibited tree establishment, and slowed upward movement of treelines on a time scale of decades. Interspecific interactions are major processes controlling treeline dynamics that may account for the absence of an upward shift at some TP treelines despite continued climatic warming. PMID:27044083

Species interactions slow warming-induced upward shifts of treelines on the Tibetan Plateau.

Science.gov (United States)

Liang, Eryuan; Wang, Yafeng; Piao, Shilong; Lu, Xiaoming; Camarero, Jesús Julio; Zhu, Haifeng; Zhu, Liping; Ellison, Aaron M; Ciais, Philippe; Peñuelas, Josep

2016-04-19

The alpine treeline is commonly regarded as being sensitive to climatic warming because regeneration and growth of trees at treeline generally are limited by low temperature. The alpine treelines of the Tibetan Plateau (TP) occur at the highest elevations (4,900 m above sea level) in the Northern Hemisphere. Ongoing climatic warming is expected to shift treelines upward. Studies of treeline dynamics at regional and local scales, however, have yielded conflicting results, indicating either unchanging treeline elevations or upward shifts. To reconcile this conflict, we reconstructed in detail a century of treeline structure and tree recruitment at sites along a climatic gradient of 4 °C and mean annual rainfall of 650 mm on the eastern TP. Species interactions interacted with effects of warming on treeline and could outweigh them. Densification of shrubs just above treeline inhibited tree establishment, and slowed upward movement of treelines on a time scale of decades. Interspecific interactions are major processes controlling treeline dynamics that may account for the absence of an upward shift at some TP treelines despite continued climatic warming.

The impact of edge gradients in the pressure, density, ion temperature, and electron temperature on edge-localized modes

International Nuclear Information System (INIS)

Kleva, Robert G.; Guzdar, Parvez N.

2011-01-01

The magnitude of the energy and particle fluxes in simulations of edge-localized modes (ELMs) is determined by the edge gradients in the pressure, density, ion temperature, and electron temperature. The total edge pressure gradient is the dominant influence on ELMs by far. An increase (decrease) of merely 2% in the pressure gradient results in an increase (decrease) of more than a factor of ten in the size of the ELM bursts. At a fixed pressure gradient, the size of the ELM bursts decreases as the density gradient increases, while the size of the bursts increases as the electron temperature gradient or, especially, the ion temperature gradient increases.

Spectroscopic analysis of the density and temperature gradients in the laser-heated gas jet

International Nuclear Information System (INIS)

Matthews, D.L.; Lee, R.W.; Auerbach, J.M.

1981-01-01

We have performed an analysis of the x-ray spectra produced by a 1.0TW, lambda/sub L/-0.53μm laser-irradiated gas jet. Plasmas produced by ionization of neon, argon and N 2 + SF 6 gases were included in those measurements. Plasma electron density and temperature gradients were obtained by comparison of measured spectra with those produced by computer modeling. Density gradients were also obtained using laser interferometry. The limitations of this technique for plasma diagnosis will be discussed

Oxygen transport by oxygen potential gradient in dense ceramic oxide membranes

Energy Technology Data Exchange (ETDEWEB)

Maiya, P.S.; Balachandran, U.; Dusek, J.T.; Mieville, R.L. [Argonne National Lab., IL (United States). Energy Technology Div.; Kleefisch, M.S.; Udovich, C.A. [Amoco Exploration/Production, Naperville, IL (United States)

1996-05-01

Numerous studies have been conducted in recent years on the partial oxidation of methane to synthesis gas (syngas: CO + H{sub 2}) with air as the oxidant. In partial oxidation, a mixed-oxide ceramic membrane selectively transports oxygen from the air; this transport is driven by the oxygen potential gradient. Of the several ceramic materials the authors have tested, a mixed oxide based on the Sr-Fe-Co-O system has been found to be very attractive. Extensive oxygen permeability data have been obtained for this material in methane conversion experiments carried out in a reactor. The data have been analyzed by a transport equation based on the phenomenological theory of diffusion under oxygen potential gradients. Thermodynamic calculations were used to estimate the driving force for the transport of oxygen ions. The results show that the transport equation deduced from the literature describes the permeability data reasonably well and can be used to determine the diffusion coefficients and the associated activation energy of oxygen ions in the ceramic membrane material.

Directed transport by surface chemical potential gradients for enhancing analyte collection in nanoscale sensors.

Science.gov (United States)

Sitt, Amit; Hess, Henry

2015-05-13

Nanoscale detectors hold great promise for single molecule detection and the analysis of small volumes of dilute samples. However, the probability of an analyte reaching the nanosensor in a dilute solution is extremely low due to the sensor's small size. Here, we examine the use of a chemical potential gradient along a surface to accelerate analyte capture by nanoscale sensors. Utilizing a simple model for transport induced by surface binding energy gradients, we study the effect of the gradient on the efficiency of collecting nanoparticles and single and double stranded DNA. The results indicate that chemical potential gradients along a surface can lead to an acceleration of analyte capture by several orders of magnitude compared to direct collection from the solution. The improvement in collection is limited to a relatively narrow window of gradient slopes, and its extent strongly depends on the size of the gradient patch. Our model allows the optimization of gradient layouts and sheds light on the fundamental characteristics of chemical potential gradient induced transport.

A modified gradient approach for the growth of low-density InAs quantum dot molecules by molecular beam epitaxy

Science.gov (United States)

Sharma, Nandlal; Reuter, Dirk

2017-11-01

Two vertically stacked quantum dots that are electronically coupled, so called quantum dot molecules, are of great interest for the realization of solid state building blocks for quantum communication networks. We present a modified gradient approach to realize InAs quantum dot molecules with a low areal density so that single quantum dot molecules can be optically addressed. The individual quantum dot layers were prepared by solid source molecular beam epitaxy depositing InAs on GaAs(100). The bottom quantum dot layer has been grown without substrate rotation resulting in an In-gradient across the surface, which translated into a density gradient with low quantum dot density in a certain region of the wafer. For the top quantum dot layer, separated from the bottom quantum dot layer by a 6 nm thick GaAs barrier, various InAs amounts were deposited without an In-gradient. In spite of the absence of an In-gradient, a pronounced density gradient is observed for the top quantum dots. Even for an In-amount slightly below the critical thickness for a single dot layer, a density gradient in the top quantum dot layer, which seems to reproduce the density gradient in the bottom layer, is observed. For more or less In, respectively, deviations from this behavior occur. We suggest that the obvious influence of the bottom quantum dot layer on the growth of the top quantum dots is due to the strain field induced by the buried dots.

Effects of population density and chemical environment on the behavior of Escherichia coli in shallow temperature gradients

International Nuclear Information System (INIS)

Demir, Mahmut; Yoney, Anna; Salman, Hanna; Douarche, Carine; Libchaber, Albert

2011-01-01

In shallow temperature gradients, changes in temperature that bacteria experience occur over long time scales. Therefore, slow processes such as adaptation, metabolism, chemical secretion and even gene expression become important. Since these are cellular processes, the cell density is an important parameter that affects the bacteria's response. We find that there are four density regimes with distinct behaviors. At low cell density, bacteria do not cause changes in their chemical environment; however, their response to the temperature gradient is strongly influenced by it. In the intermediate cell-density regime, the consumption of nutrients becomes significant and induces a gradient of nutrients opposing the temperature gradient due to higher consumption rate at the high temperature. This causes the bacteria to drift toward low temperature. In the high cell-density regime, interactions among bacteria due to secretion of an attractant lead to a strong local accumulation of bacteria. This together with the gradient of nutrients, resulted from the differential consumption rate, creates a fast propagating pulse of bacterial density. These observations are a result of classical nonlinear population dynamics. At extremely high cell density, a change in the physiological state of the bacteria is observed. The bacteria, at the individual level, become cold seeking. This appears initially as a result of a change in the methylation level of the two most abundant sensing receptors, Tsr and Tar. It is further enforced at an even higher cell density by a change in the expression level of these receptors. (perspective)

Fluid and gyrokinetic modelling of particle transport in plasmas with hollow density profiles

International Nuclear Information System (INIS)

Tegnered, D; Oberparleiter, M; Nordman, H; Strand, P

2016-01-01

Hollow density profiles occur in connection with pellet fuelling and L to H transitions. A positive density gradient could potentially stabilize the turbulence or change the relation between convective and diffusive fluxes, thereby reducing the turbulent transport of particles towards the center, making the fuelling scheme inefficient. In the present work, the particle transport driven by ITG/TE mode turbulence in regions of hollow density profiles is studied by fluid as well as gyrokinetic simulations. The fluid model used, an extended version of the Weiland transport model, Extended Drift Wave Model (EDWM), incorporates an arbitrary number of ion species in a multi-fluid description, and an extended wavelength spectrum. The fluid model, which is fast and hence suitable for use in predictive simulations, is compared to gyrokinetic simulations using the code GENE. Typical tokamak parameters are used based on the Cyclone Base Case. Parameter scans in key plasma parameters like plasma β, R/L T , and magnetic shear are investigated. It is found that β in particular has a stabilizing effect in the negative R/L n region, both nonlinear GENE and EDWM show a decrease in inward flux for negative R/L n and a change of direction from inward to outward for positive R/L n . This might have serious consequences for pellet fuelling of high β plasmas. (paper)

The causal relation between turbulent particle flux and density gradient

Energy Technology Data Exchange (ETDEWEB)

Milligen, B. Ph. van; Martín de Aguilera, A.; Hidalgo, C. [CIEMAT - Laboratorio Nacional de Fusión, Avda. Complutense 40, 28040 Madrid (Spain); Carreras, B. A. [BACV Solutions, 110 Mohawk Road, Oak Ridge, Tennessee 37830 (United States); García, L.; Nicolau, J. H. [Universidad Carlos III, 28911 Leganés, Madrid (Spain)

2016-07-15

A technique for detecting the causal relationship between fluctuating signals is used to investigate the relation between flux and gradient in fusion plasmas. Both a resistive pressure gradient driven turbulence model and experimental Langmuir probe data from the TJ-II stellarator are studied. It is found that the maximum influence occurs at a finite time lag (non-instantaneous response) and that quasi-periodicities exist. Furthermore, the model results show very long range radial influences, extending over most of the investigated regions, possibly related to coupling effects associated with plasma self-organization. These results clearly show that transport in fusion plasmas is not local and instantaneous, as is sometimes assumed.

Implementation of a one-group interfacial area transport equation in a CFD code for the simulation of upward adiabatic bubbly flow

International Nuclear Information System (INIS)

Pellacani, F.; Macian, R.; Chiva, S.; Pena, C.

2011-01-01

In this paper upward, isothermal and turbulent bubbly flow in tubes is numerically modeled by using ANSYS CFX 12.1 with the aim of creating a basis for the reliable simulation of the flow along a vertical channel in a nuclear reactor as long term goal. Two approaches based on the mono-dispersed model and on the one-group Interfacial Area Transport Equation (IATE) model are used in order to maintain the computational effort as low as possible. This work represents the necessary step to implement a two-group interfacial area transport equation that will be able to dynamically represent the changes in interfacial structure in the transition region from bubbly to slug flow. The drag coefficient is calculated using the Grace model and the interfacial non-drag forces are also included. The Antal model is used for the calculation of the wall lubrication force coefficient. The lift force coefficient is obtained from the Tomiyama model. The turbulent dispersion force is taken into account and is modeled using the FAD (Favre averaged drag) approach, while the turbulence transfer is simulated with the Sato's model. The liquid velocity is in the range between 0.5 and 2 m/s and the average void fraction varies between 5 and 15%.The source and sink terms for break-up and coalescence needed for the calculation of the implemented Interfacial Area Density are those proposed by Yao and Morel. The model has been checked using experimental results by Mendez. Radial profile distributions of void fraction, interfacial area density and bubble mean diameter are shown at the axial position equivalent to z/D=56. The results obtained by the simulations have a good agreement with the experimental data but show also the need of a better study of the coalescence and breakup phenomena to develop more accurate interaction models. (author)

Preparation of synaptic plasma membrane and postsynaptic density proteins using a discontinuous sucrose gradient.

Science.gov (United States)

Bermejo, Marie Kristel; Milenkovic, Marija; Salahpour, Ali; Ramsey, Amy J

2014-09-03

Neuronal subcellular fractionation techniques allow the quantification of proteins that are trafficked to and from the synapse. As originally described in the late 1960's, proteins associated with the synaptic plasma membrane can be isolated by ultracentrifugation on a sucrose density gradient. Once synaptic membranes are isolated, the macromolecular complex known as the post-synaptic density can be subsequently isolated due to its detergent insolubility. The techniques used to isolate synaptic plasma membranes and post-synaptic density proteins remain essentially the same after 40 years, and are widely used in current neuroscience research. This article details the fractionation of proteins associated with the synaptic plasma membrane and post-synaptic density using a discontinuous sucrose gradient. Resulting protein preparations are suitable for western blotting or 2D DIGE analysis.

Density gradient effect on waveguide launching of lower hybrid waves

International Nuclear Information System (INIS)

Fichet, M.; Fidone, I.

1981-01-01

An extensive numerical investigation of the waveguide-plasma coupling, in the lower hybrid range of frequencies, is presented. The role of a sharp density gradient at the plasma edge is investigated. It is found that, in the case of a very sharp gradient, the accessibility condition |nsub(parallel)|>nsub(c)=(1-ω 2 /ωsub(i)ωsub(e))sup(-1/2) is violated and an appreciable fraction of the total energy is launched in the range |nsub(parallel)|< nsub(c). The case of one, two and four waveguides is considered, and it is found that the general pattern of the energy spectrum is very similar for the three antennas. (author)

Reflection and absorption of ion-acoustic waves in a plasma density gradient

International Nuclear Information System (INIS)

Ishihara, O.

1977-01-01

Plasma is characterized by electrical quasineutrality and the collective behavior. There exists a longitudinal low-frequency wave called an ion-acoustic wave in a plasma. One problem in the experimental study of ion-acoustic waves has been that sometimes they are observed to be reflected from discharge tube walls, and sometimes to be absorbed. Theoretical computation reveals that a velocity gradient produced by a density gradient plays a significant role in the reflection. The velocity gradient produces the subsonic-supersonic transition and long wavelength waves are reflected before reaching the transition while short wavelength waves penetrate over the transition and are absorbed in the supersonic flow plasma

Multi-Dimensional Quantum Effect Simulation Using a Density-Gradient Model and Script-Level Programming Techniques

Science.gov (United States)

Rafferty, Connor S.; Biegel, Bryan A.; Yu, Zhi-Ping; Ancona, Mario G.; Bude, J.; Dutton, Robert W.; Saini, Subhash (Technical Monitor)

1998-01-01

A density-gradient (DG) model is used to calculate quantum-mechanical corrections to classical carrier transport in MOS (Metal Oxide Semiconductor) inversion/accumulation layers. The model is compared to measured data and to a fully self-consistent coupled Schrodinger and Poisson equation (SCSP) solver. Good agreement is demonstrated for MOS capacitors with gate oxide as thin as 21 A. It is then applied to study carrier distribution in ultra short MOSFETs (Metal Oxide Semiconductor Field Effect Transistor) with surface roughness. This work represents the first implementation of the DG formulation on multidimensional unstructured meshes. It was enabled by a powerful scripting approach which provides an easy-to-use and flexible framework for solving the fourth-order PDEs (Partial Differential Equation) of the DG model.

Instability and transport driven by an electron temperature gradient close to critical

International Nuclear Information System (INIS)

Dong, J.Q.; Jian, G.D.; Wang, A.K.; Sanuki, H.; Itoh, K.

2003-01-01

Electron temperature gradient (ETG) driven instability in toroidal plasmas is studied with gyrokinetic theory. The full electron kinetics is considered. The upgraded numerical scheme for solving the integral eigenvalue equations allows the study of both growing and damping modes, and thus direct calculation of critical gradient. Algebraic formulas for the critical gradient with respect to ratio of electron temperature over ion temperature and to toroidicity are given. An estimation for turbulence induced transport is presented. (author)

Vertical density gradient in the eastern North Atlantic during the last 30,000 years

Energy Technology Data Exchange (ETDEWEB)

Rogerson, M.; Ramirez, J. [University of Hull, Geography Department, Hull (United Kingdom); Bigg, G.R. [University of Sheffield, Department of Geography, Sheffield (United Kingdom); Rohling, E.J. [University of Southampton, National Oceanography Centre, School of Ocean and Earth Science, Southampton (United Kingdom)

2012-08-15

Past changes in the density and momentum structure of oceanic circulation are an important aspect of changes in the Atlantic Meridional Overturning Circulation and consequently climate. However, very little is known about past changes in the vertical density structure of the ocean, even very extensively studied systems such as the North Atlantic. Here we exploit the physical controls on the settling depth of the dense Mediterranean water plume derived from the Strait of Gibraltar to obtain the first robust, observations-based, probabilistic reconstruction of the vertical density gradient in the eastern North Atlantic during the last 30,000 years. We find that this gradient was weakened by more than 50%, relative to the present, during the last Glacial Maximum, and that changes in general are associated with reductions in AMOC intensity. However, we find only a small change during Heinrich Event 1 relative to the Last Glacial Maximum, despite strong evidence that overturning was substantially altered. This implies that millennial-scale changes may not be reflected in vertical density structure of the ocean, which may be limited to responses on an ocean-overturning timescale or longer. Regardless, our novel reconstruction of Atlantic density structure can be used as the basis for a dynamical measure for validation of model-based AMOC reconstructions. In addition, our general approach is transferrable to other marginal sea outflow plumes, to provide estimates of oceanic vertical density gradients in other locations. (orig.)

Correcting the error in neutron moisture probe measurements caused by a water density gradient

International Nuclear Information System (INIS)

Wilson, D.J.

1988-01-01

If a neutron probe lies in or near a water density gradient, the probe may register a water density different to that at the measuring point. The effect of a thin stratum of soil containing an excess or depletion of water at various distances from a probe in an otherwise homogeneous system has been calculated, producing an 'importance' curve. The effect of these strata can be integrated over the soil region in close proximity to the probe resulting in the net effect of the presence of a water density gradient. In practice, the probe is scanned through the point of interest and the count rate at that point is corrected for the influence of the water density on each side of it. An example shows that the technique can reduce an error of 10 per cent to about 2 per cent

Analytic calculations of hyper-Raman spectra from density functional theory hyperpolarizability gradients

Energy Technology Data Exchange (ETDEWEB)

Ringholm, Magnus; Ruud, Kenneth [Centre for Theoretical and Computational Chemistry, Department of Chemistry, University of Tromsø – The Arctic University of Norway, 9037 Tromsø (Norway); Bast, Radovan [Theoretical Chemistry and Biology, School of Biotechnology, Royal Institute of Technology, AlbaNova University Center, S-10691 Stockholm (Sweden); PDC Center for High Performance Computing, Royal Institute of Technology, S-10044 Stockholm (Sweden); Oggioni, Luca [Centre for Theoretical and Computational Chemistry, Department of Chemistry, University of Tromsø – The Arctic University of Norway, 9037 Tromsø (Norway); Department of Physics G. Occhialini, University of Milano Bicocca, Piazza della scienza 3, 20126 Milan (Italy); Ekström, Ulf [Centre for Theoretical and Computational Chemistry, Department of Chemistry, University of Oslo, P.O. Box 1033 Blindern, 0315 Oslo (Norway)

2014-10-07

We present the first analytic calculations of the geometrical gradients of the first hyperpolarizability tensors at the density-functional theory (DFT) level. We use the analytically calculated hyperpolarizability gradients to explore the importance of electron correlation effects, as described by DFT, on hyper-Raman spectra. In particular, we calculate the hyper-Raman spectra of the all-trans and 11-cis isomers of retinal at the Hartree-Fock (HF) and density-functional levels of theory, also allowing us to explore the sensitivity of the hyper-Raman spectra on the geometrical characteristics of these structurally related molecules. We show that the HF results, using B3LYP-calculated vibrational frequencies and force fields, reproduce the experimental data for all-trans-retinal well, and that electron correlation effects are of minor importance for the hyper-Raman intensities.

Current Density Functional Theory Using Meta-Generalized Gradient Exchange-Correlation Functionals.

Science.gov (United States)

Furness, James W; Verbeke, Joachim; Tellgren, Erik I; Stopkowicz, Stella; Ekström, Ulf; Helgaker, Trygve; Teale, Andrew M

2015-09-08

We present the self-consistent implementation of current-dependent (hybrid) meta-generalized gradient approximation (mGGA) density functionals using London atomic orbitals. A previously proposed generalized kinetic energy density is utilized to implement mGGAs in the framework of Kohn-Sham current density functional theory (KS-CDFT). A unique feature of the nonperturbative implementation of these functionals is the ability to seamlessly explore a wide range of magnetic fields up to 1 au (∼235 kT) in strength. CDFT functionals based on the TPSS and B98 forms are investigated, and their performance is assessed by comparison with accurate coupled-cluster singles, doubles, and perturbative triples (CCSD(T)) data. In the weak field regime, magnetic properties such as magnetizabilities and nuclear magnetic resonance shielding constants show modest but systematic improvements over generalized gradient approximations (GGA). However, in the strong field regime, the mGGA-based forms lead to a significantly improved description of the recently proposed perpendicular paramagnetic bonding mechanism, comparing well with CCSD(T) data. In contrast to functionals based on the vorticity, these forms are found to be numerically stable, and their accuracy at high field suggests that the extension of mGGAs to CDFT via the generalized kinetic energy density should provide a useful starting point for further development of CDFT approximations.

Electric field spikes formed by electron beam endash plasma interaction in plasma density gradients

International Nuclear Information System (INIS)

Gunell, H.; Loefgren, T.

1997-01-01

In the electron beam endash plasma interaction at an electric double layer the beam density is much higher than in the classical beam endash plasma experiments. The wave propagation takes place along the density gradient that is present at the high potential side of the double layer. Such a case is studied experimentally by injecting the electron beam from a plane cathode, without any grids suppressing the gradient, and by particle simulations. The high frequency field concentrates in a sharp open-quotes spikeclose quotes with a half width of the order of one wavelength. The spike is found to be a standing wave surrounded by regions dominated by propagating waves. It forms at a position where its frequency is close to the local plasma frequency. The spike forms also when the electric field is well below the threshold for modulational instability, and long before a density cavity is formed in the simulations. Particle simulations reveal that, at the spike, there is a backward traveling wave that, when it is strongly damped, accelerates electrons back towards the cathode. In a simulation of a homogeneous plasma without the density gradient no spike is seen, and the wave is purely travelling instead of standing. copyright 1997 American Institute of Physics

Analytic energy gradients for the coupled-cluster singles and doubles method with the density-fitting approximation

International Nuclear Information System (INIS)

Bozkaya, Uğur; Sherrill, C. David

2016-01-01

An efficient implementation is presented for analytic gradients of the coupled-cluster singles and doubles (CCSD) method with the density-fitting approximation, denoted DF-CCSD. Frozen core terms are also included. When applied to a set of alkanes, the DF-CCSD analytic gradients are significantly accelerated compared to conventional CCSD for larger molecules. The efficiency of our DF-CCSD algorithm arises from the acceleration of several different terms, which are designated as the “gradient terms”: computation of particle density matrices (PDMs), generalized Fock-matrix (GFM), solution of the Z-vector equation, formation of the relaxed PDMs and GFM, back-transformation of PDMs and GFM to the atomic orbital (AO) basis, and evaluation of gradients in the AO basis. For the largest member of the alkane set (C 10 H 22 ), the computational times for the gradient terms (with the cc-pVTZ basis set) are 2582.6 (CCSD) and 310.7 (DF-CCSD) min, respectively, a speed up of more than 8-folds. For gradient related terms, the DF approach avoids the usage of four-index electron repulsion integrals. Based on our previous study [U. Bozkaya, J. Chem. Phys. 141, 124108 (2014)], our formalism completely avoids construction or storage of the 4-index two-particle density matrix (TPDM), using instead 2- and 3-index TPDMs. The DF approach introduces negligible errors for equilibrium bond lengths and harmonic vibrational frequencies.

Medicinal Plants Density Along an Altitudinal Gradient in and Around Ayubia National Park

International Nuclear Information System (INIS)

Tariq, A.; Adnan, M.; Begum, S.

2016-01-01

Medicinal plants are an essential source of livelihood for many rural populations and are currently facing several threats of extinction in temperate Himalaya, such as excessive grazing and collection along altitudinal gradients. The present study was designed to investigate the species density of medicinal plants at different mid-altitude levels (2200, 2300, 2400, and 2500 m above the sea level (a.s.l.) between two forest-use types and to examine the possible association between medicinal plant densities and forest-stand structural variables along the altitudinal gradient. Factorial design analysis of variance showed that the densities of all medicinal plants differed significantly between the forest-use types (p<0.00) and elevation (p<0.00). Moreover, a significant interaction (p<0.04) was also observed between the forest-use types and elevation. In the old-growth forest, density of medicinal plants was 290/40 m/sup 2/ at the higher altitude (2500 m a.s.l.), approximately 1.5-fold less than the 475/40 m/sup 2/ density observed at lower altitude (2200 m a.s.l.). However, in derived woodland, density of medicinal plants at higher altitude was approximately 4-fold less than that at the lower altitude. At these altitudinal levels, medicinal plants densities, such as Valeriana jatamansi, were significantly higher under old-growth forest compared to derived woodland, where they were almost nonexistent. A rapid vulnerability assessment has also shown that Valeriana jatamansi and Viola canescens were highly vulnerable species. Litter cover was the influential variable that was most likely related to medicinal plant density. In conclusion, abundance of medicinal plants decreased along mid-altitude levels in both of the forest-use types. However, this decrease was extremely marked in the derived woodland, and this decline may be due to human activity. Hence, these factors must be considered in future studies to suggest protective measures that can be applied along

The boundary condition for vertical velocity and its interdependence with surface gas exchange

Science.gov (United States)

Kowalski, Andrew S.

2017-07-01

The law of conservation of linear momentum is applied to surface gas exchanges, employing scale analysis to diagnose the vertical velocity (w) in the boundary layer. Net upward momentum in the surface layer is forced by evaporation (E) and defines non-zero vertical motion, with a magnitude defined by the ratio of E to the air density, as w = E/ρ. This is true even right down at the surface where the boundary condition is w|0 = E/ρ|0 (where w|0 and ρ|0 represent the vertical velocity and density of air at the surface). This Stefan flow velocity implies upward transport of a non-diffusive nature that is a general feature of the troposphere but is of particular importance at the surface, where it assists molecular diffusion with upward gas migration (of H2O, for example) but opposes that of downward-diffusing species like CO2 during daytime. The definition of flux-gradient relationships (eddy diffusivities) requires rectification to exclude non-diffusive transport, which does not depend on scalar gradients. At the microscopic scale, the role of non-diffusive transport in the process of evaporation from inside a narrow tube - with vapour transport into an overlying, horizontal airstream - was described long ago in classical mechanics and is routinely accounted for by chemical engineers, but has been neglected by scientists studying stomatal conductance. Correctly accounting for non-diffusive transport through stomata, which can appreciably reduce net CO2 transport and marginally boost that of water vapour, should improve characterisations of ecosystem and plant functioning.

Travelling waves of density for a fourth-gradient model of fluids

Science.gov (United States)

Gouin, Henri; Saccomandi, Giuseppe

2016-09-01

In mean-field theory, the non-local state of fluid molecules can be taken into account using a statistical method. The molecular model combined with a density expansion in Taylor series of the fourth order yields an internal energy value relevant to the fourth-gradient model, and the equation of isothermal motions takes then density's spatial derivatives into account for waves travelling in both liquid and vapour phases. At equilibrium, the equation of the density profile across interfaces is more precise than the Cahn and Hilliard equation, and near the fluid's critical point, the density profile verifies an Extended Fisher-Kolmogorov equation, allowing kinks, which converges towards the Cahn-Hillard equation when approaching the critical point. Nonetheless, we also get pulse waves oscillating and generating critical opalescence.

Removal of heavy metals from kaolin using an upward electrokinetic soil remedial (UESR) technology

International Nuclear Information System (INIS)

Wang, J.-Y.; Huang, X.-J.; Kao, Jimmy C.M.; Stabnikova, Olena

2006-01-01

An upward electrokinetic soil remedial (UESR) technology was proposed to remove heavy metals from contaminated kaolin. Unlike conventional electrokinetic treatment that uses boreholes or trenches for horizontal migration of heavy metals, the UESR technology, applying vertical non-uniform electric fields, caused upward transportation of heavy metals to the top surface of the treated soil. The effects of current density, treatment duration, cell diameter, and different cathode chamber influent (distilled water or 0.01 M nitric acid) were studied. The removal efficiencies of heavy metals positively correlated to current density and treatment duration. Higher heavy metals removal efficiency was observed for the reactor cell with smaller diameter. A substantial amount of heavy metals was accumulated in the nearest to cathode 2 cm layer of kaolin when distilled water was continuously supplied to the cathode chamber. Heavy metals accumulated in this layer of kaolin can be easily excavated and disposed off. The main part of the removed heavy metals was dissolved in cathode chamber influent and moved away with cathode chamber effluent when 0.01 M nitric acid was used, instead of distilled water. Energy saving treatment by UESR technology with highest metal removal efficiencies was provided by two regimes: (1) by application of 0.01 M nitric acid as cathode chamber influent, cell diameter of 100 mm, duration of 18 days, and constant voltage of 3.5 V (19.7 kWh/m 3 of kaolin) and (2) by application of 0.01 M nitric acid as cathode chamber influent, cell diameter of 100 cm, duration of 6 days, and constant current density of 0.191 mA/cm 2 (19.1 kWh/m 3 of kaolin)

High frequency electric field spikes formed by electron beam-plasma interaction in plasma density gradients

International Nuclear Information System (INIS)

Gunell, H.; Loefgren, T.

1997-02-01

In the electron beam-plasma interaction at an electric double layer the beam density is much higher than in the classical beam-plasma experiments. The wave propagation takes place along the density gradient, that is present at the high potential side of the double layer. Such a case is studied experimentally by injecting the electron beam from a plane cathode, without any grids suppressing the gradient, and by particle simulations. The high frequency field concentrates in a sharp 'spike' with a half width of the order of one wavelength. The spike is found to be a standing wave surrounded by regions dominated by propagating waves. It forms at a position where its frequency is close to the local plasma frequency. The spike forms also when the electric field is well below the threshold for modulational instability, and long before a density cavity is formed in the simulations. Particle simulations reveal that, at the spike, there is a backward travelling wave that, when it is strongly damped, accelerates electrons back towards the cathode. In a simulation of a homogeneous plasma without the density gradient no spike is seen, and the wave is purely travelling instead of standing. 9 refs

Thermoelectric properties of high electron concentration materials under large temperature gradients

International Nuclear Information System (INIS)

Bulat, L.P.; Stefansky, V.A.

1994-01-01

Theoretical methods of investigating of transport properties in solids under large temperature gradients are grounded. The nonlinear and non-local expressions for current density and heat flow are obtained with degenerated of current carriers gas. A number of new effects with large temperature gradients have been tested. Use of large temperature gradients leads to the increasing of the thermoelectric figure of merit. copyright 1995 American Institute of Physics

High Ra, high Pr convection with viscosity gradients

Indian Academy of Sciences (India)

First page Back Continue Last page Overview Graphics. High Ra, high Pr convection with viscosity gradients. Weak upward flow through mesh. Top fluid more viscous. Unstable layer Instability Convection.

Anomalous plasma transport due to electron temperature gradient instability

International Nuclear Information System (INIS)

Tokuda, Sinji; Ito, Hiroshi; Kamimura, Tetsuo.

1979-01-01

The collisionless drift wave instability driven by an electron temperature inhomogeneity (electron temperature gradient instability) and the enhanced transport processes associated with it are studied using a two-and-a-half dimensional particle simulation code. The simulation results show that quasilinear diffusion in phase space is an important mechanism for the saturation of the electron temperature gradient instability. Also, the instability yields particle fluxes toward the hot plasma regions. The heat conductivity of the electron temperature perpendicular to the magnetic field, T sub(e'), is not reduced by magnetic shear but remains high, whereas the heat conductivity of the parallel temperature, T sub(e''), is effectively reduced, and the instability stabilized. (author)

Effects of low central fuelling on density and ion temperature profiles in reversed shear plasmas on JT-60U

Energy Technology Data Exchange (ETDEWEB)

Takenaga, H; Ide, S; Sakamoto, Y; Fujita, T [Japan Atomic Energy Agency, Naka Ibaraki 311-0193 (Japan)], E-mail: takenaga.hidenobu@jaea.go.jp

2008-07-15

Effects of low central fuelling on density and ion temperature profiles have been investigated using negative ion based neutral beam injection and electron cyclotron heating (ECH) in reversed shear plasmas on JT-60U. Strong internal transport barrier (ITB) was maintained in density and ion temperature profiles, when central fuelling was decreased by switching positive ion based neutral beam injection to ECH after the strong ITB formation. Similar density and ion temperature ITBs were formed for the low and high central fuelling cases during the plasma current ramp-up phase. Strong correlation between the density gradient and the ion temperature gradient was observed, indicating that particle transport and ion thermal transport are strongly coupled or the density gradient assists the ion temperature ITB formation through suppression of drift wave instabilities such as ion temperature gradient mode. These results support that the density and ion temperature ITBs can be formed under reactor relevant conditions.

Effects of low central fuelling on density and ion temperature profiles in reversed shear plasmas on JT-60U

Science.gov (United States)

Takenaga, H.; Ide, S.; Sakamoto, Y.; Fujita, T.; JT-60 Team

2008-07-01

Effects of low central fuelling on density and ion temperature profiles have been investigated using negative ion based neutral beam injection and electron cyclotron heating (ECH) in reversed shear plasmas on JT-60U. Strong internal transport barrier (ITB) was maintained in density and ion temperature profiles, when central fuelling was decreased by switching positive ion based neutral beam injection to ECH after the strong ITB formation. Similar density and ion temperature ITBs were formed for the low and high central fuelling cases during the plasma current ramp-up phase. Strong correlation between the density gradient and the ion temperature gradient was observed, indicating that particle transport and ion thermal transport are strongly coupled or the density gradient assists the ion temperature ITB formation through suppression of drift wave instabilities such as ion temperature gradient mode. These results support that the density and ion temperature ITBs can be formed under reactor relevant conditions.

Interfacial area transport of vertical upward air-water two-phase flow in an annulus at elevated pressures

International Nuclear Information System (INIS)

Ozar, Basar; Hibiki, Takashi; Ishii, Mamoru; Euh, Dong-Jin

2009-01-01

The interfacial area transport of vertical, upward, air-water two-phase flows in an annular channel has been investigated at different system pressures. The inner and outer diameters of the annular channel were 19.1 mm and 38.1 mm, respectively. Twenty three inlet flow conditions were selected, which coverED bubbly, cap-slug, and churn-turbulent flows. These flow conditions also overlapped with twelve conditions of our previous study for comparison. The local flow parameters, such as void fractions, interfacial area concentrations (IAC), and bubble interface velocities, were measured at nine radial positions for the three axial locations (z/D h =52, 149 and 230) and converted into area-averaged parameters. The axial evolutions of local flow structure was interpreted in terms of bubble coalescence, breakup, expansion of the gas-phase due to pressure drop and system pressure. An assessment of interfacial area transport equation (IATE) was made and compared with the experimental data. A discussion of the comparison between model prediction and the experimental results were made. (author)

Assessment of plasma impedance probe for measuring electron density and collision frequency in a plasma with spatial and temporal gradients

International Nuclear Information System (INIS)

Hopkins, Mark A.; King, Lyon B.

2014-01-01

Numerical simulations and experimental measurements were combined to determine the ability of a plasma impedance probe (PIP) to measure plasma density and electron collision frequency in a plasma containing spatial gradients as well as time-varying oscillations in the plasma density. A PIP is sensitive to collision frequency through the width of the parallel resonance in the Re[Z]-vs.-frequency characteristic, while also being sensitive to electron density through the zero-crossing of the Im[Z]-vs.-frequency characteristic at parallel resonance. Simulations of the probe characteristic in a linear plasma gradient indicated that the broadening of Re[Z] due to the spatial gradient obscured the broadening due to electron collision frequency, preventing a quantitative measurement of the absolute collision frequency for gradients considered in this study. Simulation results also showed that the PIP is sensitive to relative changes in electron collision frequency in a spatial density gradient, but a second broadening effect due to time-varying oscillations made collision frequency measurements impossible. The time-varying oscillations had the effect of causing multiple zero-crossings in Im[Z] at parallel resonance. Results of experiments and simulations indicated that the lowest-frequency zero-crossing represented the lowest plasma density in the oscillations and the highest-frequency zero-crossing represented the highest plasma density in the oscillations, thus the PIP probe was found to be an effective tool to measure both the average plasma density as well as the maximum and minimum densities due to temporal oscillations

High density internal transport barriers for burning plasma operation

International Nuclear Information System (INIS)

Pericoli Ridolfini, V.

2005-01-01

One of the proposed ITER scenarios foresees the creation and sustainment of an internal transport barrier (ITB) in order to improve the confinement properties of the hot core plasma. The more stringent requests are: the ITB must be sustained with electron heating only with no or very small external momentum source, the strong collisional coupling at the envisaged density (line average >1.0 1020 m-3) must not prevent the barrier existence, the bootstrap current created by the large induced gradients must have a radial profile consistent with that requested by the barrier creation and sustainment. To all these items the studies carried out in FTU in the same density range (ne0 ?1.5 1020 m-3) provide encouraging prospects. With pure electron heating and current drive (LH+ECH) steady electron barrier are generated and maintained with central e- temperature >5.0 keV. Almost full CD conditions are established with a bootstrap current close to 25% of the total and well aligned with that driven by the LH waves and responsible for the barrier building. The clear change in the density fluctuations close to the ITB radius, observed by reflectometry, indicates stabilization of turbulence that is consistent with the drop of the thermal electron diffusivity inside the ITB to very low values, ?e<0.5 m2/s estimated by the transport analysis. The 10 fold neutron rate increase testifies a significant collisional ion heating, even though usually ?Ti0/Ti0 does not exceed 40%, because the e--i + equipartition time, always 4-5 times longer than the energy confinement time, does not allow thermal equilibrium with electrons to be attained. The ion thermal diffusivity inside the barrier must be lowered to the neoclassical level to account for the observed Ti(r) profiles, clearly indicating at least a non-degraded ion transport. The global confinement in turn improves by 1.6 times above the FTU L-scaling. The ITB radius can be controlled by varying the LH power deposition profile that is

Mineral density volume gradients in normal and diseased human tissues.

Directory of Open Access Journals (Sweden)

Sabra I Djomehri

Full Text Available Clinical computed tomography provides a single mineral density (MD value for heterogeneous calcified tissues containing early and late stage pathologic formations. The novel aspect of this study is that, it extends current quantitative methods of mapping mineral density gradients to three dimensions, discretizes early and late mineralized stages, identifies elemental distribution in discretized volumes, and correlates measured MD with respective calcium (Ca to phosphorus (P and Ca to zinc (Zn elemental ratios. To accomplish this, MD variations identified using polychromatic radiation from a high resolution micro-computed tomography (micro-CT benchtop unit were correlated with elemental mapping obtained from a microprobe X-ray fluorescence (XRF using synchrotron monochromatic radiation. Digital segmentation of tomograms from normal and diseased tissues (N=5 per group; 40-60 year old males contained significant mineral density variations (enamel: 2820-3095 mg/cc, bone: 570-1415 mg/cc, cementum: 1240-1340 mg/cc, dentin: 1480-1590 mg/cc, cementum affected by periodontitis: 1100-1220 mg/cc, hypomineralized carious dentin: 345-1450 mg/cc, hypermineralized carious dentin: 1815-2740 mg/cc, and dental calculus: 1290-1770 mg/cc. A plausible linear correlation between segmented MD volumes and elemental ratios within these volumes was established, and Ca/P ratios for dentin (1.49, hypomineralized dentin (0.32-0.46, cementum (1.51, and bone (1.68 were observed. Furthermore, varying Ca/Zn ratios were distinguished in adapted compared to normal tissues, such as in bone (855-2765 and in cementum (595-990, highlighting Zn as an influential element in prompting observed adaptive properties. Hence, results provide insights on mineral density gradients with elemental concentrations and elemental footprints that in turn could aid in elucidating mechanistic processes for pathologic formations.

Mineral Density Volume Gradients in Normal and Diseased Human Tissues

Science.gov (United States)

Djomehri, Sabra I.; Candell, Susan; Case, Thomas; Browning, Alyssa; Marshall, Grayson W.; Yun, Wenbing; Lau, S. H.; Webb, Samuel; Ho, Sunita P.

2015-01-01

Clinical computed tomography provides a single mineral density (MD) value for heterogeneous calcified tissues containing early and late stage pathologic formations. The novel aspect of this study is that, it extends current quantitative methods of mapping mineral density gradients to three dimensions, discretizes early and late mineralized stages, identifies elemental distribution in discretized volumes, and correlates measured MD with respective calcium (Ca) to phosphorus (P) and Ca to zinc (Zn) elemental ratios. To accomplish this, MD variations identified using polychromatic radiation from a high resolution micro-computed tomography (micro-CT) benchtop unit were correlated with elemental mapping obtained from a microprobe X-ray fluorescence (XRF) using synchrotron monochromatic radiation. Digital segmentation of tomograms from normal and diseased tissues (N=5 per group; 40-60 year old males) contained significant mineral density variations (enamel: 2820-3095mg/cc, bone: 570-1415mg/cc, cementum: 1240-1340mg/cc, dentin: 1480-1590mg/cc, cementum affected by periodontitis: 1100-1220mg/cc, hypomineralized carious dentin: 345-1450mg/cc, hypermineralized carious dentin: 1815-2740mg/cc, and dental calculus: 1290-1770mg/cc). A plausible linear correlation between segmented MD volumes and elemental ratios within these volumes was established, and Ca/P ratios for dentin (1.49), hypomineralized dentin (0.32-0.46), cementum (1.51), and bone (1.68) were observed. Furthermore, varying Ca/Zn ratios were distinguished in adapted compared to normal tissues, such as in bone (855-2765) and in cementum (595-990), highlighting Zn as an influential element in prompting observed adaptive properties. Hence, results provide insights on mineral density gradients with elemental concentrations and elemental footprints that in turn could aid in elucidating mechanistic processes for pathologic formations. PMID:25856386

Comparison of preconditioned generalized conjugate gradient methods to two-dimensional neutron and photon transport equation

International Nuclear Information System (INIS)

Chen, G.S.; Yang, D.Y.

1998-01-01

We apply and compare the preconditioned generalized conjugate gradient methods to solve the linear system equation that arises in the two-dimensional neutron and photon transport equation in this paper. Several subroutines are developed on the basis of preconditioned generalized conjugate gradient methods for time-independent, two-dimensional neutron and photon transport equation in the transport theory. These generalized conjugate gradient methods are used: TFQMR (transpose free quasi-minimal residual algorithm) CGS (conjugate gradient square algorithm), Bi-CGSTAB (bi-conjugate gradient stabilized algorithm) and QMRCGSTAB (quasi-minimal residual variant of bi-conjugate gradient stabilized algorithm). These subroutines are connected to computer program DORT. Several problems are tested on a personal computer with Intel Pentium CPU. The reasons to choose the generalized conjugate gradient methods are that the methods have better residual (equivalent to error) control procedures in the computation and have better convergent rate. The pointwise incomplete LU factorization ILU, modified pointwise incomplete LU factorization MILU, block incomplete factorization BILU and modified blockwise incomplete LU factorization MBILU are the preconditioning techniques used in the several testing problems. In Bi-CGSTAB, CGS, TFQMR and QMRCGSTAB method, we find that either CGS or Bi-CGSTAB method combined with preconditioner MBILU is the most efficient algorithm in these methods in the several testing problems. The numerical solution of flux by preconditioned CGS and Bi-CGSTAB methods has the same result as those from Cray computer, obtained by either the point successive relaxation method or the line successive relaxation method combined with Gaussian elimination

Ion-temperature-gradient-driven modes in bi-ion magnetoplasma

Energy Technology Data Exchange (ETDEWEB)

Batool, Nazia; Mirza, Arshad M [Theoretical Plasma Physics Group, Department of Physics, Quaid-i-Azam University, Islamabad 45320 (Pakistan); Qamar, Anisa [Department of Physics, Peshawar University, NWFP 25120 (Pakistan)], E-mail: nazia.batool@ncp.edu.pk

2008-12-15

The toroidal ion-temperature-gradient (ITG)-driven electrostatic drift waves are investigated for bi-ion plasmas with equilibrium density, temperature and magnetic field gradients. Using Braginskii's transport equations for the ions and Boltzmann distributed electrons, the mode coupling equations are derived. New ITG-driven modes are shown to exist. The results of the present study should be helpful to understand several wave phenomena in space and tokamak plasmas.

Ion temperature gradient driven transport in a density modification experiment on the TFTR tokamak

International Nuclear Information System (INIS)

Horton, W.; Lindberg, D.; Kim, J.Y.; Dong, J.Q.; Hammett, G.W.; Scott, S.D.; Zarnstorff, M.C.; Hamaguchi, S.

1991-07-01

TFTR profiles from a supershot density-modification experiment are analyzed for their local and ballooning stability to toroidal η i -modes in order to understand the initially puzzling results showing no increase in X i when a pellet is used to produce an abrupt and large increase in the η i parameter. The local stability analysis assumes that k parallel = 1/qR and ignores the effects of shear, but makes no assumption on the magnitude of k parallel v ti /ω. The ballooning stability analysis determines a self-consistent linear spectrum of k parallel's including the effect of shear and toroidicity, but it expands in k parallel v ti /ω ≤ 1, which is a marginal assumption for this experiment. Nevertheless, the two approaches agree well and show that the mixing length estimate of the transport rate does not change appreciably during the density-modification and has a value close to or less than the observed X i , in contrast to most previous theories which predicted X i 's which were over an order-of-magnitude too large. However, we are still unable to explain the observed increase X i (r) with minor radius by adding the effects of the finite beta drift - MHD mode coupling, the slab-like mode, or the trapped electron response. The experimental tracking 0.2 e /X i i and trapped-electron driving mechanisms are operating. 4 refs., 5 figs., 5 tabs

Transportable charge in a periodic alternating gradient system

International Nuclear Information System (INIS)

Lee, E.P.; Fessenden, T.J.; Laslett, L.J.

1985-05-01

A simple set of formulas is derived which relate emittance, line charge density, matched maximum and average envelope radii, occupancy factors, and the (space charge) depressed and vacuum values of tune. This formulation is an improvement on the smooth limit approximation; deviations from exact (numerically determined) relations are on the order of +-2%, while the smooth limit values are in error by up to +-30%. This transport formalism is used to determine the limits of transportable line charge density in an electrostatic quadrupole array, with specific application to the low energy portion of the High Temperature Experiment of Heavy Ion Fusion Accelerator Research. The line charge density limit is found to be essentially proportional to the voltage on the pole faces and the fraction of occupied aperture area. A finite injection energy (greater than or equal to 2 MeV) is required to realize this limit, independent of particle mass

Theory and observations of upward field-aligned currents at the magnetopause boundary layer.

Science.gov (United States)

Wing, Simon; Johnson, Jay R

2015-11-16

The dependence of the upward field-aligned current density ( J ‖ ) at the dayside magnetopause boundary layer is well described by a simple analytic model based on a velocity shear generator. A previous observational survey confirmed that the scaling properties predicted by the analytical model are applicable between 11 and 17 MLT. We utilize the analytic model to predict field-aligned currents using solar wind and ionospheric parameters and compare with direct observations. The calculated and observed parallel currents are in excellent agreement, suggesting that the model may be useful to infer boundary layer structures. However, near noon, where velocity shear is small, the kinetic pressure gradients and thermal currents, which are not included in the model, could make a small but significant contribution to J ‖ . Excluding data from noon, our least squares fit returns log( J ‖,max_cal ) = (0.96 ± 0.04) log( J ‖_obs ) + (0.03 ± 0.01) where J ‖,max_cal = calculated J ‖,max and J ‖_obs = observed J ‖ .

The boundary condition for vertical velocity and its interdependence with surface gas exchange

Directory of Open Access Journals (Sweden)

A. S. Kowalski

2017-07-01

Full Text Available The law of conservation of linear momentum is applied to surface gas exchanges, employing scale analysis to diagnose the vertical velocity (w in the boundary layer. Net upward momentum in the surface layer is forced by evaporation (E and defines non-zero vertical motion, with a magnitude defined by the ratio of E to the air density, as w = E/ρ. This is true even right down at the surface where the boundary condition is w|0 = E/ρ|0 (where w|0 and ρ|0 represent the vertical velocity and density of air at the surface. This Stefan flow velocity implies upward transport of a non-diffusive nature that is a general feature of the troposphere but is of particular importance at the surface, where it assists molecular diffusion with upward gas migration (of H2O, for example but opposes that of downward-diffusing species like CO2 during daytime. The definition of flux–gradient relationships (eddy diffusivities requires rectification to exclude non-diffusive transport, which does not depend on scalar gradients. At the microscopic scale, the role of non-diffusive transport in the process of evaporation from inside a narrow tube – with vapour transport into an overlying, horizontal airstream – was described long ago in classical mechanics and is routinely accounted for by chemical engineers, but has been neglected by scientists studying stomatal conductance. Correctly accounting for non-diffusive transport through stomata, which can appreciably reduce net CO2 transport and marginally boost that of water vapour, should improve characterisations of ecosystem and plant functioning.

Fast-electron self-collimation in a plasma density gradient

International Nuclear Information System (INIS)

Yang, X. H.; Borghesi, M.; Robinson, A. P. L.

2012-01-01

A theoretical and numerical study of fast electron transport in solid and compressed fast ignition relevant targets is presented. The principal aim of the study is to assess how localized increases in the target density (e.g., by engineering of the density profile) can enhance magnetic field generation and thus pinching of the fast electron beam through reducing the rate of temperature rise. The extent to which this might benefit fast ignition is discussed.

The effect of shear flow and the density gradient on the Weibel instability growth rate in the dense plasma

Science.gov (United States)

Amininasab, S.; Sadighi-Bonabi, R.; Khodadadi Azadboni, F.

2018-02-01

Shear stress effect has been often neglected in calculation of the Weibel instability growth rate in laser-plasma interactions. In the present work, the role of the shear stress in the Weibel instability growth rate in the dense plasma with density gradient is explored. By increasing the density gradient, the shear stress threshold is increasing and the range of the propagation angles of growing modes is limited. Therefore, by increasing steps of the density gradient plasma near the relativistic electron beam-emitting region, the Weibel instability occurs at a higher stress flow. Calculations show that the minimum value of the stress rate threshold for linear polarization is greater than that of circular polarization. The Wiebel instability growth rate for linear polarization is 18.3 times circular polarization. One sees that for increasing stress and density gradient effects, there are smaller maximal growth rates for the range of the propagation angles of growing modes /π 2 propagation angles of growing modes /π 2 < θ m i n < π and /3 π 2 < θ m i n < 2 π in circular polarized plasma.

The role of fluctuation-induced transport in a toroidal plasma with strong radial electric fields

Science.gov (United States)

Roth, J. R.; Krawczonek, W. M.; Powers, E. J.; Hong, J. Y.; Kim, Y. C.

1981-01-01

Previous work employing digitally implemented spectral analysis techniques is extended to demonstrate that radial fluctuation-induced transport is the dominant ion transport mechanism in an electric field dominated toroidal plasma. Such transport can be made to occur against a density gradient, and hence may have a very beneficial effect on confinement in toroidal plasmas of fusion interest. It is shown that Bohm or classical diffusion down a density gradient, the collisional Pedersen-current mechanism, and the collisionless electric field gradient mechanism described by Cole (1976) all played a minor role, if any, in the radial transport of this plasma.

Method and means for a spatial and temporal probe for laser-generated plumes based on density gradients

Science.gov (United States)

Yeung, E.S.; Chen, G.

1990-05-01

A method and means are disclosed for a spatial and temporal probe for laser generated plumes based on density gradients includes generation of a plume of vaporized material from a surface by an energy source. The probe laser beam is positioned so that the plume passes through the probe laser beam. Movement of the probe laser beam caused by refraction from the density gradient of the plume is monitored. Spatial and temporal information, correlated to one another, is then derived. 15 figs.

Observations of wave-induced pore pressure gradients and bed level response on a surf zone sandbar

Science.gov (United States)

Anderson, Dylan; Cox, Dan; Mieras, Ryan; Puleo, Jack A.; Hsu, Tian-Jian

2017-06-01

Horizontal and vertical pressure gradients may be important physical mechanisms contributing to onshore sediment transport beneath steep, near-breaking waves in the surf zone. A barred beach was constructed in a large-scale laboratory wave flume with a fixed profile containing a mobile sediment layer on the crest of the sandbar. Horizontal and vertical pore pressure gradients were obtained by finite differences of measurements from an array of pressure transducers buried within the upper several centimeters of the bed. Colocated observations of erosion depth were made during asymmetric wave trials with wave heights between 0.10 and 0.98 m, consistently resulting in onshore sheet flow sediment transport. The pore pressure gradient vector within the bed exhibited temporal rotations during each wave cycle, directed predominantly upward under the trough and then rapidly rotating onshore and downward as the wavefront passed. The magnitude of the pore pressure gradient during each phase of rotation was correlated with local wave steepness and relative depth. Momentary bed failures as deep as 20 grain diameters were coincident with sharp increases in the onshore-directed pore pressure gradients, but occurred at horizontal pressure gradients less than theoretical critical values for initiation of the motion for compact beds. An expression combining the effects of both horizontal and vertical pore pressure gradients with bed shear stress and soil stability is used to determine that failure of the bed is initiated at nonnegligible values of both forces.type="synopsis">type="main">Plain Language SummaryThe pressure gradient present within the seabed beneath breaking waves may be an important physical mechanism transporting sediment. A large-scale laboratory was used to replicate realistic surfzone conditions in controlled tests, allowing for horizontal and vertical pressure gradient magnitudes and the resulting sediment bed response to be observed with precise instruments

Subsystem density functional theory with meta-generalized gradient approximation exchange-correlation functionals.

Science.gov (United States)

Śmiga, Szymon; Fabiano, Eduardo; Laricchia, Savio; Constantin, Lucian A; Della Sala, Fabio

2015-04-21

We analyze the methodology and the performance of subsystem density functional theory (DFT) with meta-generalized gradient approximation (meta-GGA) exchange-correlation functionals for non-bonded molecular systems. Meta-GGA functionals depend on the Kohn-Sham kinetic energy density (KED), which is not known as an explicit functional of the density. Therefore, they cannot be directly applied in subsystem DFT calculations. We propose a Laplacian-level approximation to the KED which overcomes this limitation and provides a simple and accurate way to apply meta-GGA exchange-correlation functionals in subsystem DFT calculations. The so obtained density and energy errors, with respect to the corresponding supermolecular calculations, are comparable with conventional approaches, depending almost exclusively on the approximations in the non-additive kinetic embedding term. An embedding energy error decomposition explains the accuracy of our method.

Relationship between particle and heat transport in JT-60U plasmas with internal transport barrier

International Nuclear Information System (INIS)

Takenaga, H.; Higashijima, S.; Oyama, N.

2003-01-01

The relationship between particle and heat transport in an internal transport barrier (ITB) has been systematically investigated in reversed shear (RS) and high β p ELMy H-mode plasmas in JT-60U. No helium and carbon accumulation inside the ITB is observed even with ion heat transport reduced to a neoclassical level. On the other hand, the heavy impurity argon is accumulated inside the ITB. The argon density profile estimated from the soft x-ray profile is more peaked, by a factor of 2-4 in the RS plasma and of 1.6 in the high β p mode plasma, than the electron density profile. The helium diffusivity (D He ) and the ion thermal diffusivity (χ i ) are at an anomalous level in the high β p mode plasma, where D He and χ i are higher by a factor of 5-10 than the neoclassical value. In the RS plasma, D He is reduced from the anomalous to the neoclassical level, together with χ i . The carbon and argon density profiles calculated using the transport coefficients reduced to the neoclassical level only in the ITB are more peaked than the measured profiles, even when χ i is reduced to the neoclassical level. Argon exhaust from the inside of the ITB is demonstrated by applying ECH in the high β p mode plasma, where both electron and argon density profiles become flatter. The reduction of the neoclassical inward velocity for argon due to the reduction of density gradient is consistent with the experimental observation. In the RS plasma, the density gradient is not decreased by ECH and argon is not exhausted. These results suggest the importance of density gradient control to suppress heavy impurity accumulation. (author)

Application of GelGreen™ in Cesium Chloride Density Gradients for DNA-Stable Isotope Probing Experiments.

Directory of Open Access Journals (Sweden)

Jingfeng Gao

Full Text Available In this study, GelGreen™ was investigated as a replacement for SYBR® Safe to stain DNA in cesium chloride (CsCl density gradients for DNA-stable isotope probing (SIP experiments. Using environmental DNA, the usage of GelGreen™ was optimized for sensitivity compared to SYBR® Safe, its optimal concentration, detection limit for environmental DNA and its application in environmental DNA-SIP assay. Results showed that GelGreen™ was more sensitive than SYBR® Safe, while the optimal dosage (15X concentration needed was approximately one-third of SYBR® Safe, suggesting that its sensitivity was three times more superior than SYBR® Safe. At these optimal parameters, the detection limit of GelGreen™-stained environmental DNA was as low as 0.2 μg, but the usage of 0.5 μg environmental DNA was recommended to produce a more consistent DNA band. In addition, a modified needle extraction procedure was developed to withdraw DNA effectively by fractionating CsCl density gradients into four or five fractions. The successful application of GelGreen™ staining with 13C-labeled DNA from enriched activated sludge suggests that this stain was an excellent alternative of SYBR® Safe in CsCl density gradients for DNA-SIP assays.

Conjugate-gradient optimization method for orbital-free density functional calculations.

Science.gov (United States)

Jiang, Hong; Yang, Weitao

2004-08-01

Orbital-free density functional theory as an extension of traditional Thomas-Fermi theory has attracted a lot of interest in the past decade because of developments in both more accurate kinetic energy functionals and highly efficient numerical methodology. In this paper, we developed a conjugate-gradient method for the numerical solution of spin-dependent extended Thomas-Fermi equation by incorporating techniques previously used in Kohn-Sham calculations. The key ingredient of the method is an approximate line-search scheme and a collective treatment of two spin densities in the case of spin-dependent extended Thomas-Fermi problem. Test calculations for a quartic two-dimensional quantum dot system and a three-dimensional sodium cluster Na216 with a local pseudopotential demonstrate that the method is accurate and efficient. (c) 2004 American Institute of Physics.

Density gradient in SiO 2 films on silicon as revealed by positron annihilation spectroscopy

Science.gov (United States)

Revesz, A. G.; Anwand, W.; Brauer, G.; Hughes, H. L.; Skorupa, W.

2002-06-01

Positron annihilation spectroscopy of thermally grown and deposited SiO 2 films on silicon shows in a non-destructive manner that these films have a gradient in their density. The gradient is most pronounced for the oxide grown in dry oxygen. Oxidation in water-containing ambient results in an oxide with reduced gradient, similarly to the gradient in the deposited oxide. These observations are in accordance with earlier optical and other studies using stepwise etching or a set of samples of varying thickness. The effective oxygen charge, which is very likely one of the reasons for the difference in the W parameters of silica glass and quartz crystal, could be even higher at some localized configurations in the SiO 2 films resulting in increased positron trapping.

Space-charge limits on the transport of ion beams in a long alternating gradient system

International Nuclear Information System (INIS)

Tiefenback, M.G.

1986-11-01

We have experimentally studied the space-charge-dominated transport of ion beams in an alternating-gradient channel, without acceleration. We parameterize the focusing strength in terms of the zero-current ''betatron'' oscillation phase advance rate, σ 0 (degrees per focusing period). We have investigated the conditions for ''stability'', defined as the constancy of the total current and phase space area of the beam during transport. We find that the beam may be transported with neither loss of current nor growth in phase area if σ 0 0 . In this regime, the space-charge repulsive force can counter 98-99% of the externally applied focusing field, and the oscillation frequency of the beam particles can be depressed by self-forces to almost a factor of 10 below the zero-current value, limited only by the optical quality of our ion source. For σ 0 > 90 0 , we find that collective interactions bound the maintainable density of the beam, and we present a simple, semi-empirical characterization for stability, within our ability to distinguish the growth rate from zero in our apparatus. Our channel comprises 87 quadrupole lenses, 5 of which are used to prepare the beam for injection into the non-azimuthally-symmetric focusing channel

Isolation of human salivary extracellular vesicles by iodixanol density gradient ultracentrifugation and their characterizations

Directory of Open Access Journals (Sweden)

Kazuya Iwai

2016-05-01

Full Text Available Diagnostic methods that focus on the extracellular vesicles (EVs present in saliva have been attracting great attention because of their non-invasiveness. EVs contain biomolecules such as proteins, messenger RNA (mRNA and microRNA (miRNA, which originate from cells that release EVs, making them an ideal source for liquid biopsy. Although there have been many reports on density-based fractionation of EVs from blood and urine, the number of reports on EVs from saliva has been limited, most probably because of the difficulties in separating EVs from viscous saliva using density gradient centrifugation. This article establishes a protocol for the isolation of EVs from human saliva using density gradient centrifugation. The fractionated salivary EVs were characterized by atomic force microscopy, western blot and reverse transcription polymerase chain reaction. The results indicate that salivary EVs have a smaller diameter (47.8±12.3 nm and higher density (1.11 g/ml than EVs isolated from conditioned cell media (74.0±23.5 nm and 1.06 g/ml, respectively. Additionally, to improve the throughput of density-based fractionation of EVs, the original protocol was further modified by using a fixed angle rotor instead of a swinging rotor. It was also confirmed that several miRNAs were expressed strongly in the EV-marker-expressing fractions.

Coherent resonance stop bands in alternating gradient beam transport

Science.gov (United States)

Ito, K.; Okamoto, H.; Tokashiki, Y.; Fukushima, K.

2017-06-01

An extensive experimental study is performed to confirm fundamental resonance bands of an intense hadron beam propagating through an alternating gradient linear transport channel. The present work focuses on the most common lattice geometry called "FODO" or "doublet" that consists of two quadrupoles of opposite polarities. The tabletop ion-trap system "S-POD" (Simulator of Particle Orbit Dynamics) developed at Hiroshima University is employed to clarify the parameter-dependence of coherent beam instability. S-POD can provide a non-neutral plasma physically equivalent to a charged-particle beam in a periodic focusing potential. In contrast with conventional experimental approaches relying on large-scale machines, it is straightforward in S-POD to control the doublet geometry characterized by the quadrupole filling factor and drift-space ratio. We verify that the resonance feature does not essentially change depending on these geometric factors. A few clear stop bands of low-order resonances always appear in the same pattern as previously found with the sinusoidal focusing model. All stop bands become widened and shift to the higher-tune side as the beam density is increased. In the space-charge-dominated regime, the most dangerous stop band is located at the bare betatron phase advance slightly above 90 degrees. Experimental data from S-POD suggest that this severe resonance is driven mainly by the linear self-field potential rather than by nonlinear external imperfections and, therefore, unavoidable at high beam density. The instability of the third-order coherent mode generates relatively weak but noticeable stop bands near the phase advances of 60 and 120 degrees. The latter sextupole stop band is considerably enhanced by lattice imperfections. In a strongly asymmetric focusing channel, extra attention may have to be paid to some coupling resonance lines induced by the Coulomb potential. Our interpretations of experimental data are supported by theoretical

Pitfalls of using the geometric-mean combining rule in the density gradient theory

DEFF Research Database (Denmark)

Liang, Xiaodong; Michelsen, Michael Locht; Kontogeorgis, Georgios

2016-01-01

It is popular and attractive to model the interfacial tension using the density gradient theory with the geometric-mean combining rule, in which the same equation of state is used for the interface and bulk phases. The computational efficiency is the most important advantage of this theory. In th...

Transport rates and concentration gradients during grain filling in wheat

International Nuclear Information System (INIS)

Fisher, D.B.; Gifford, R.M.

1986-01-01

Short-term mass transport rates into wheat ears were calculated at mid grain fill from 32 PO 4 translocation velocities and sieve tube sap concentrations in the peduncle. Over a wide range of velocities (8.5 to 170 cm/hr), sieve tube sap concentrations (514 to 1050 milliosmolal) and grains per ear (20 to 54 in intact ears, as few as 7 in partially degrained ears), there were no evident differences in the rate of mass transport per grain through the peduncle. Increased sieve tube sap concentration was accompanied in the endosperm cavity sap by increased sucrose concentration, but amino acid concentration and total osmolality remained essentially constant. Thus the rate of transport into the grains appeared to remain constant in spite of altered concentration gradients across the crease tissues of the grain and changing sucrose concentration in the endosperm cavity. The constancy of endosperm cavity sap osmolality suggests that osmoregulatory processes in the grain may play a role in regulating transport rate into the grain

CORONAL DENSITY STRUCTURE AND ITS ROLE IN WAVE DAMPING IN LOOPS

Energy Technology Data Exchange (ETDEWEB)

Cargill, P. J. [Space and Atmospheric Physics, The Blackett Laboratory, Imperial College, London SW7 2BW (United Kingdom); De Moortel, I.; Kiddie, G., E-mail: p.cargill@imperial.ac.uk [School of Mathematics and Statistics, University of St Andrews, St Andrews, Scotland KY16 9SS (United Kingdom)

2016-05-20

It has long been established that gradients in the Alfvén speed, and in particular the plasma density, are an essential part of the damping of waves in the magnetically closed solar corona by mechanisms such as resonant absorption and phase mixing. While models of wave damping often assume a fixed density gradient, in this paper the self-consistency of such calculations is assessed by examining the temporal evolution of the coronal density. It is shown conceptually that for some coronal structures, density gradients can evolve in a way that the wave-damping processes are inhibited. For the case of phase mixing we argue that (a) wave heating cannot sustain the assumed density structure and (b) inclusion of feedback of the heating on the density gradient can lead to a highly structured density, although on long timescales. In addition, transport coefficients well in excess of classical are required to maintain the observed coronal density. Hence, the heating of closed coronal structures by global oscillations may face problems arising from the assumption of a fixed density gradient, and the rapid damping of oscillations may have to be accompanied by a separate (non-wave-based) heating mechanism to sustain the required density structuring.

Effects of bunch density gradient in high-gain free-electron lasers

International Nuclear Information System (INIS)

Huang, Z.; Kim, K.-J.

1999-01-01

The authors investigate effects of the bunch density gradient in self-amplified spontaneous emission (SASE), including the role of coherent spontaneous emission (CSE) in the evolution of the free-electron laser (FEL) process. In the exponential gain regime, the authors solve the coupled Maxwell-Vlasov equations and extend the linear theory to a bunched beam with energy spread. A time-dependent, nonlinear simulation algorithm is used to study the CSE effect and the nonlinear evolution of the radiation pulse

Bone marrow-derived cells for cardiovascular cell therapy: an optimized GMP method based on low-density gradient improves cell purity and function.

Science.gov (United States)

Radrizzani, Marina; Lo Cicero, Viviana; Soncin, Sabrina; Bolis, Sara; Sürder, Daniel; Torre, Tiziano; Siclari, Francesco; Moccetti, Tiziano; Vassalli, Giuseppe; Turchetto, Lucia

2014-09-27

Cardiovascular cell therapy represents a promising field, with several approaches currently being tested. The advanced therapy medicinal product (ATMP) for the ongoing METHOD clinical study ("Bone marrow derived cell therapy in the stable phase of chronic ischemic heart disease") consists of fresh mononuclear cells (MNC) isolated from autologous bone marrow (BM) through density gradient centrifugation on standard Ficoll-Paque. Cells are tested for safety (sterility, endotoxin), identity/potency (cell count, CD45/CD34/CD133, viability) and purity (contaminant granulocytes and platelets). BM-MNC were isolated by density gradient centrifugation on Ficoll-Paque. The following process parameters were optimized throughout the study: gradient medium density; gradient centrifugation speed and duration; washing conditions. A new manufacturing method was set up, based on gradient centrifugation on low density Ficoll-Paque, followed by 2 washing steps, of which the second one at low speed. It led to significantly higher removal of contaminant granulocytes and platelets, improving product purity; the frequencies of CD34+ cells, CD133+ cells and functional hematopoietic and mesenchymal precursors were significantly increased. The methodological optimization described here resulted in a significant improvement of ATMP quality, a crucial issue to clinical applications in cardiovascular cell therapy.

Density gradients in the solar plasma observed by interplanetary scintillation

International Nuclear Information System (INIS)

Gapper, G.R.; Hewish, A.

1981-01-01

A new technique is described which overcomes the limitation set by Fresnel filtering in previous IPS studies of the small-scale density irregularities in the solar plasma. Phase gradients introduced by irregularities larger than the Fresnel limit cause transverse displacements of the small-scale scintillation pattern. In the presence of the solar wind, such refraction effects may be revealed by simultaneous measurements of intensity scintillation at two radio frequencies. Observations show that the structure corresponding to temporal frequencies approximately 0.02 Hz is in agreement with an extrapolation of the Kolmogorov spectrum derived from spacecraft data at lower frequencies. (author)

Plasma-edge gradients in L-mode and ELM-free H-mode JET plasmas

International Nuclear Information System (INIS)

Breger, P.; Zastrow, K.-D.; Davies, S.J.; K ig, R.W.T.; Summers, D.D.R.; Hellermann, M.G. von; Flewin, C.; Hawkes, N.C.; Pietrzyk, Z.A.; Porte, L.

1998-01-01

Experimental plasma-edge gradients in JET during the edge-localized-mode (ELM) free H-mode are examined for evidence of the presence and location of the transport barrier region inside the magnetic separatrix. High spatial resolution data in electron density is available in- and outside the separatrix from an Li-beam diagnostic, and in electron temperature inside the separatrix from an ECE diagnostic, while outside the separatrix, a reciprocating probe provides electron density and temperature data in the scrape-off layer. Ion temperatures and densities are measured using an edge charge-exchange diagnostic. A comparison of observed widths and gradients of this edge region with each other and with theoretical expectations is made. Measurements show that ions and electrons form different barrier regions. Furthermore, the electron temperature barrier width (3-4 cm) is about twice that of electron density, in conflict with existing scaling laws. Suitable parametrization of the edge data enables an electron pressure gradient to be deduced for the first time at JET. It rises during the ELM-free phase to reach only about half the marginal pressure gradient expected from ballooning stability before the first ELM. Subsequent type I ELMs occur on a pressure gradient contour roughly consistent with both a constant barrier width model and a ballooning mode envelope model. (author)

Role of the current density profile on drift wave stability in internal transport barrier reversed magnetic shear experiments at JET and Tore Supra

Energy Technology Data Exchange (ETDEWEB)

Fourment, C; Hoang, G T; Eriksson, L-G; Garbet, X; Litaudon, X; Tresset, G [EURATOM-CEA Association, CEA/DSM/DRFC, CEA Cadarache, 13108 St Paul-lez-Durance (France)

2003-03-01

The role of the current density profile on drift wave stability is investigated using a linear electrostatic gyro-kinetic code. The growth rates are shown to have a linear dependence on the normalized temperature gradients above a certain threshold. A parametric study of the threshold shows a dramatic stabilizing effect of negative magnetic shear, especially for large scale instabilities. A set of handy formulae fitting the threshold as a function of the magnetic shear and the safety factor is proposed. Analysis of reversed magnetic shear discharges with internal transport barrier (ITB) in JET shows that ion ITBs can be triggered by the negative magnetic shear in the core of the plasma. Subsequently, the increase of the ExB shearing rate allows for the expansion of the ITB, despite the increase of the linear growth rates due to the temperature gradient peaking. In the case of the electron ITB obtained in the Tore Supra LHEP mode, the central increase of the confinement is associated with the stabilization of large scale trapped electron modes by the negative magnetic shear effect, whereas the steep electron temperature gradient destabilizes the small scale electron temperature gradient modes, which prevent the electron heat transport to reach neoclassical levels.

Characterisation of temperature gradient driven turbulence and transport

International Nuclear Information System (INIS)

Ottaviani, M.A.

2002-01-01

We report on extensive numerical studies aimed at characterising various aspects of temperature gradient driven turbulence. We specifically discuss results from 3D fluid models of ETG and of ITG turbulence, and results from a 2D+2D gyrokinetic model of trapped ion turbulence. Global transport exhibits gyro-Bohm scaling in both the ETG and the ITG model. The conductivity of the ETG model decreases weakly with beta. The heat transport is due to the EXB advection, the effect of the magnetic flutter is negligible. However the transport level is much lower than experimentally observed. In both 3D models the correlation lengths scale with the gyroradius, but they are typically a factor 10 larger. Vortices are elongated but their aspect ratio is independent of the gyroradius. Their radial size is limited by LD. The trapped ion model gives larger vortices due to the absence of LD from passing ions. Avalanches are observed in all the models, the weakest occurring in the ITG system. Their range increases with gyroradius, but more weakly than linearly. Finally, ZFs can limit the range of the avalanches, which explains why avalanches are weaker in the ITG model which is more sensitive to ZFs. (author)

Near-surface temperature gradient in a coastal upwelling regime

Science.gov (United States)

Maske, H.; Ochoa, J.; Almeda-Jauregui, C. O.; Ruiz-de la Torre, M. C.; Cruz-López, R.; Villegas-Mendoza, J. R.

2014-08-01

In oceanography, a near homogeneous mixed layer extending from the surface to a seasonal thermocline is a common conceptual basis in physics, chemistry, and biology. In a coastal upwelling region 3 km off the coast in the Mexican Pacific, we measured vertical density gradients with a free-rising CTD and temperature gradients with thermographs at 1, 3, and 5 m depths logging every 5 min during more than a year. No significant salinity gradient was observed down to 10 m depth, and the CTD temperature and density gradients showed no pronounced discontinuity that would suggest a near-surface mixed layer. Thermographs generally logged decreasing temperature with depth with gradients higher than 0.2 K m-1 more than half of the time in the summer between 1 and 3 m, 3 and 5 m and in the winter between 1 and 3 m. Some negative temperature gradients were present and gradients were generally highly variable in time with high peaks lasting fractions of hours to hours. These temporal changes were too rapid to be explained by local heating or cooling. The pattern of positive and negative peaks might be explained by vertical stacks of water layers of different temperatures and different horizontal drift vectors. The observed near-surface gradient has implications for turbulent wind energy transfer, vertical exchange of dissolved and particulate water constituents, the interpretation of remotely sensed SST, and horizontal wind-induced transport.

Investigation of one-dimensional interfacial area transport for vertical upward air–water two-phase flow in an annular channel at elevated pressures

International Nuclear Information System (INIS)

Ozar, B.; Brooks, C.S.; Euh, D.J.; Hibiki, T.; Ishii, M.

2013-01-01

Highlights: • Interfacial area transport equation (IATE) for a rectangular duct is modified for an annulus. • IATE predicts interfacial area transport in bubbly-to-churn flow. • Scalability of IATE to elevated pressure conditions is validated. • Detailed 1D interfacial area transport data are presented. • Detailed interfacial area transport mechanisms are discussed. -- Abstract: The interfacial area transport of vertical, upward, air–water two-phase flows in an annular channel has been investigated at different system pressures. The inner and outer diameters of the annular channel were 19.1 mm and 38.1 mm, respectively. Twenty three inlet flow conditions were selected, which covered bubbly, cap-bubbly, and churn-turbulent flows. These flow conditions also overlapped with twelve conditions of a previous study for comparison. The local flow parameters, such as void fractions, interfacial area concentrations (IAC), and bubble interface velocities, were measured at nine radial positions for the three axial locations and converted into area-averaged parameters. The axial evolutions of local flow structure were interpreted in terms of bubble coalescence, breakup, expansion of the gas-phase due to pressure drop and system pressure. An assessment of interfacial area transport equation (IATE) was made and compared with the experimental data. A discussion of the comparison between model prediction and the experimental results were made

Investigation of one-dimensional interfacial area transport for vertical upward air–water two-phase flow in an annular channel at elevated pressures

Energy Technology Data Exchange (ETDEWEB)

Ozar, B., E-mail: ozar@fauske.com [School of Nuclear Engineering, Purdue University, 400 Central Drive, West Lafayette, IN 47907-2017 (United States); Brooks, C.S. [School of Nuclear Engineering, Purdue University, 400 Central Drive, West Lafayette, IN 47907-2017 (United States); Euh, D.J. [Korea Atomic Energy Research Institute, 150 Deokjin, Yuseong, Daejeon 305-353 (Korea, Republic of); Hibiki, T.; Ishii, M. [School of Nuclear Engineering, Purdue University, 400 Central Drive, West Lafayette, IN 47907-2017 (United States)

2013-10-15

Highlights: • Interfacial area transport equation (IATE) for a rectangular duct is modified for an annulus. • IATE predicts interfacial area transport in bubbly-to-churn flow. • Scalability of IATE to elevated pressure conditions is validated. • Detailed 1D interfacial area transport data are presented. • Detailed interfacial area transport mechanisms are discussed. -- Abstract: The interfacial area transport of vertical, upward, air–water two-phase flows in an annular channel has been investigated at different system pressures. The inner and outer diameters of the annular channel were 19.1 mm and 38.1 mm, respectively. Twenty three inlet flow conditions were selected, which covered bubbly, cap-bubbly, and churn-turbulent flows. These flow conditions also overlapped with twelve conditions of a previous study for comparison. The local flow parameters, such as void fractions, interfacial area concentrations (IAC), and bubble interface velocities, were measured at nine radial positions for the three axial locations and converted into area-averaged parameters. The axial evolutions of local flow structure were interpreted in terms of bubble coalescence, breakup, expansion of the gas-phase due to pressure drop and system pressure. An assessment of interfacial area transport equation (IATE) was made and compared with the experimental data. A discussion of the comparison between model prediction and the experimental results were made.

Electron thermal energy transport research based on dynamical relationship between heat flux and temperature gradient

International Nuclear Information System (INIS)

Notake, Takashi; Inagaki, Shigeru; Tamura, Naoki

2008-01-01

In the nuclear fusion plasmas, both of thermal energy and particle transport governed by turbulent flow are anomalously enhanced more than neoclassical levels. Thus, to clarify a relationship between the turbulent flow and the anomalous transports has been the most worthwhile work. There are experimental results that the turbulent flow induces various phenomena on transport processes such as non-linearity, transition, hysteresis, multi-branches and non-locality. We are approaching these complicated problems by analyzing not conventional power balance but these phenomena directly. They are recognized as dynamical trajectories in the flux and gradient space and must be a clue to comprehend a physical mechanism of arcane anomalous transport. Especially, to elucidate the mechanism for electron thermal energy transport is critical in the fusion plasma researches because the burning plasmas will be sustained by alpha-particle heating. In large helical device, the dynamical relationships between electron thermal energy fluxes and electron temperature gradients are investigated by using modulated electron cyclotron resonance heating and modern electron cyclotron emission diagnostic systems. Some trajectories such as hysteresis loop or line segments with steep slope which represent non-linear property are observed in the experiment. (author)

Analysis of pedestal plasma transport

International Nuclear Information System (INIS)

Callen, J.D.; Groebner, R.J.; Osborne, T.H.; Canik, J.M.; Owen, L.W.; Pankin, A.Y.; Rafiq, T.; Rognlien, T.D.; Stacey, W.M.

2010-01-01

An H-mode edge pedestal plasma transport benchmarking exercise was undertaken for a single DIII-D pedestal. Transport modelling codes used include 1.5D interpretive (ONETWO, GTEDGE), 1.5D predictive (ASTRA) and 2D ones (SOLPS, UEDGE). The particular DIII-D discharge considered is 98889, which has a typical low density pedestal. Profiles for the edge plasma are obtained from Thomson and charge-exchange recombination data averaged over the last 20% of the average 33.53 ms repetition time between type I edge localized modes. The modelled density of recycled neutrals is largest in the divertor X-point region and causes the edge plasma source rate to vary by a factor ∼10 2 on the separatrix. Modelled poloidal variations in the densities and temperatures on flux surfaces are small on all flux surfaces up to within about 2.6 mm (ρ N > 0.99) of the mid-plane separatrix. For the assumed Fick's-diffusion-type laws, the radial heat and density fluxes vary poloidally by factors of 2-3 in the pedestal region; they are largest on the outboard mid-plane where flux surfaces are compressed and local radial gradients are largest. Convective heat flows are found to be small fractions of the electron (∼ 2 s -1 . Electron heat transport is found to be best characterized by electron-temperature-gradient-induced transport at the pedestal top and paleoclassical transport throughout the pedestal. The effective ion heat diffusivity in the pedestal has a different profile from the neoclassical prediction and may be smaller than it. The very small effective density diffusivity may be the result of an inward pinch flow nearly balancing a diffusive outward radial density flux. The inward ion pinch velocity and density diffusion coefficient are determined by a new interpretive analysis technique that uses information from the force balance (momentum conservation) equations; the paleoclassical transport model provides a plausible explanation of these new results. Finally, the measurements

Enrichment of unlabeled human Langerhans cells from epidermal cell suspensions by discontinuous density gradient centrifugation

NARCIS (Netherlands)

Teunissen, M. B.; Wormmeester, J.; Kapsenberg, M. L.; Bos, J. D.

1988-01-01

In this report we introduce an alternative procedure for enrichment of human epidermal Langerhans cells (LC) from epidermal cell suspensions of normal skin. By means of discontinuous Ficoll-Metrizoate density gradient centrifugation, a fraction containing high numbers of viable, more than 80% pure

Lateral transport of solutes in microfluidic channels using electrochemically generated gradients in redox-active surfactants.

Science.gov (United States)

Liu, Xiaoyang; Abbott, Nicholas L

2011-04-15

We report principles for a continuous flow process that can separate solutes based on a driving force for selective transport that is generated by a lateral concentration gradient of a redox-active surfactant across a microfluidic channel. Microfluidic channels fabricated with gold electrodes lining each vertical wall were used to electrochemically generate concentration gradients of the redox-active surfactant 11-ferrocenylundecyl-trimethylammonium bromide (FTMA) in a direction perpendicular to the flow. The interactions of three solutes (a hydrophobic dye, 1-phenylazo-2-naphthylamine (yellow AB), an amphiphilic molecule, 2-(4,4-difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-s-indacene-3-pentanoyl)-1-hexadecanoyl-sn-glycero-3-phosphocholine (BODIPY C(5)-HPC), and an organic salt, 1-methylpyridinium-3-sulfonate (MPS)) with the lateral gradients in surfactant/micelle concentration were shown to drive the formation of solute-specific concentration gradients. Two distinct physical mechanisms were identified to lead to the solute concentration gradients: solubilization of solutes by micelles and differential adsorption of the solutes onto the walls of the microchannels in the presence of the surfactant concentration gradient. These two mechanisms were used to demonstrate delipidation of a mixture of BODIPY C(5)-HPC (lipid) and MPS and purification of BODIPY C(5)-HPC from a mixture of BODIPY C(5)-HPC and yellow AB. Overall, the results of this study demonstrate that lateral concentration gradients of redox-active surfactants formed within microfluidic channels can be used to transport solutes across the microfluidic channels in a solute-dependent manner. The approach employs electrical potentials (solutions having high ionic strength (>0.1M), and offers the basis of continuous processes for the purification or separation of solutes in microscale systems. © 2011 American Chemical Society

Does urban sprawl hold down upward mobility?

Science.gov (United States)

Ewing, R.; Hamidi, Shima; Grace, James B.; Wei, Y.

2016-01-01

Contrary to the general perception, the United States has a much more class-bound society than other wealthy countries. The chance of upward mobility for Americans is just half that of the citizens of the Denmark and many other European countries. In addition to other influences, the built environment may contribute to the low rate of upward mobility in the U.S. This study tests the relationship between urban sprawl and upward mobility for commuting zones in the U.S. We examine potential pathways through which sprawl may have an effect on mobility. We use structural equation modeling to account for both direct and indirect effects of sprawl on upward mobility. We find that upward mobility is significantly higher in compact areas than sprawling areas. The direct effect, which we attribute to better job accessibility in more compact commuting zones, is stronger than the indirect effects. Of the indirect effects, only one, through the mediating variable income segregation, is significant.

Long-range transport of air pollution under light gradient wind conditions

International Nuclear Information System (INIS)

Kurita, H.; Sasaki, K.; Muroga, H.; Ueda, H.; Wakamatsu, S.

1985-01-01

The long-range transport of air pollution on clear days under light gradient wind conditions is investigated from an analysis of all days with high oxidant concentrations in 1979 at locations in central Japan that are far from pollutant sources. Surface-level wind and pressure distributions over a 300 x 300 km area were analyzed, together with concentration isopleths of oxidants and suspended particles produced by photochemical reactions

Theory-based transport simulation of tokamaks: density scaling

International Nuclear Information System (INIS)

Ghanem, E.S.; Kinsey, J.; Singer, C.; Bateman, G.

1992-01-01

There has been a sizeable amount of work in the past few years using theoretically based flux-surface-average transport models to simulate various types of experimental tokamak data. Here we report two such studies, concentrating on the response of the plasma to variation of the line averaged electron density. The first study reported here uses a transport model described by Ghanem et al. to examine the response of global energy confinement time in ohmically heated discharges. The second study reported here uses a closely related and more recent transport model described by Bateman to examine the response of temperature profiles to changes in line-average density in neutral-beam-heated discharges. Work on developing a common theoretical model for these and other scaling experiments is in progress. (author) 5 refs., 2 figs

Increase of volume swelling by a temperature gradient

International Nuclear Information System (INIS)

Herschbach, K.; Schneider, W.; Stober, T.

1996-11-01

The temperature gradient in the cladding of a Fast Reactor fuel pin leads to increased dilatation compared to material irradiations. Investigations of a specially designed fuel pin reached the conclusion that the cause is enhanced volume swelling. It is induced by He-bubbles, which migrate upwards the temperature gradient and coalesce. The critical size of nuclei for void swelling is thus reached much faster. Consequently, the p in deformation is larger than expected from materials irradiations, in the present case (DIN 1.4981 sa) by about 50%. (orig.) [de

Moho Density Contrast in Central Eurasia from GOCE Gravity Gradients

Directory of Open Access Journals (Sweden)

Mehdi Eshagh

2016-05-01

Full Text Available Seismic data are primarily used in studies of the Earth’s inner structure. Since large parts of the world are not yet sufficiently covered by seismic surveys, products from the Earth’s satellite observation systems have more often been used for this purpose in recent years. In this study we use the gravity-gradient data derived from the Gravity field and steady-state Ocean Circulation Explorer (GOCE, the elevation data from the Shuttle Radar Topography Mission (SRTM and other global datasets to determine the Moho density contrast at the study area which comprises most of the Eurasian plate (including parts of surrounding continental and oceanic tectonic plates. A regional Moho recovery is realized by solving the Vening Meinesz-Moritz’s (VMM inverse problem of isostasy and a seismic crustal model is applied to constrain the gravimetric solution. Our results reveal that the Moho density contrast reaches minima along the mid-oceanic rift zones and maxima under the continental crust. This spatial pattern closely agrees with that seen in the CRUST1.0 seismic crustal model as well as in the KTH1.0 gravimetric-seismic Moho model. However, these results differ considerably from some previously published gravimetric studies. In particular, we demonstrate that there is no significant spatial correlation between the Moho density contrast and Moho deepening under major orogens of Himalaya and Tibet. In fact, the Moho density contrast under most of the continental crustal structure is typically much more uniform.

Sea surface density gradients in the Nordic Seas during the Holocene as revealed by paired microfossil and isotope proxies

DEFF Research Database (Denmark)

Van Nieuwenhove, Nicolas; Hillaire-Marcel, Claude; Bauch, Henning A.

2016-01-01

We attempt to assess the Holocene surface-subsurface seawater density gradient on millennial time-scale based on the reconstruction of potential density (σθ) by combining data from dinoflagellate cyst assemblages and planktic foraminiferal (Neogloboquadrina pachyderma (s)) stable oxygen isotopes (δ...

Modified method for labeling human platelets with indium-111 oxine using albumin density-gradient separation

International Nuclear Information System (INIS)

Bunting, R.W.; Callahan, R.J.; Finkelstein, S.; Lees, R.S.; Strauss, H.W.

1982-01-01

When labeling platelets with indium-111 oxine, albumin density-gradient separation minimizes the time spent to resuspend those platelets that have been centrifuged against a hard surface. Labeling efficiency or platelet viability, as measured by platelet survival or aggregation with adenosine diphosphate, are not adversely affected

Saturation mechanism of decaying ion temperature gradient driven turbulence with kinetic electrons

International Nuclear Information System (INIS)

Idomura, Yasuhiro

2016-01-01

We present full-f gyrokinetic simulations of the ion temperature gradient driven (ITG) turbulence including kinetic electrons. By comparing decaying ITG turbulence simulations with adiabatic and kinetic electron models, an impact of kinetic electrons on the ITG turbulence is investigated. It is found that significant electron transport occurs even in the ITG turbulence, and both ion and electron temperature profiles are relaxed. In steady states, both cases show upshifts of nonlinear critical ion temperature gradients from linear ones, while their saturation mechanisms are qualitatively different. In the adiabatic electron case, the ITG mode is stabilized by turbulence driven zonal flows. On the other hand, in the kinetic electron case, passing electrons transport shows fine resonant structures at mode rational surfaces, which generate corrugated density profiles. Such corrugated density profiles lead to fine radial electric fields following the neoclassical force balance relation. The resulting E × B shearing rate greatly exceeds the linear growth rate of the ITG mode. (author)

Modelling CO2-Brine Interfacial Tension using Density Gradient Theory

KAUST Repository

Ruslan, Mohd Fuad Anwari Che

2018-03-01

Knowledge regarding carbon dioxide (CO2)-brine interfacial tension (IFT) is important for petroleum industry and Carbon Capture and Storage (CCS) strategies. In petroleum industry, CO2-brine IFT is especially importance for CO2 – based enhanced oil recovery strategy as it affects phase behavior and fluid transport in porous media. CCS which involves storing CO2 in geological storage sites also requires understanding regarding CO2-brine IFT as this parameter affects CO2 quantity that could be securely stored in the storage site. Several methods have been used to compute CO2-brine interfacial tension. One of the methods employed is by using Density Gradient Theory (DGT) approach. In DGT model, IFT is computed based on the component density distribution across the interface. However, current model is only applicable for modelling low to medium ionic strength solution. This limitation is due to the model only considers the increase of IFT due to the changes of bulk phases properties and does not account for ion distribution at interface. In this study, a new modelling strategy to compute CO2-brine IFT based on DGT was proposed. In the proposed model, ion distribution across interface was accounted for by separating the interface to two sections. The saddle point of tangent plane distance where ( ) was defined as the boundary separating the two sections of the interface. Electrolyte is assumed to be present only in the second section which is connected to the bulk liquid phase side. Numerical simulations were performed using the proposed approach for single and mixed salt solutions for three salts (NaCl, KCl, and CaCl2), for temperature (298 K to 443 K), pressure (2 MPa to 70 MPa), and ionic strength (0.085 mol·kg-1 to 15 mol·kg-1). The simulation result shows that the tuned model was able to predict with good accuracy CO2-brine IFT for all studied cases. Comparison with current DGT model showed that the proposed approach yields better match with the experiment data

A density gradient of VAPG peptides on a cell-resisting surface achieves selective adhesion and directional migration of smooth muscle cells over fibroblasts.

Science.gov (United States)

Yu, Shan; Zuo, Xingang; Shen, Tao; Duan, Yiyuan; Mao, Zhengwei; Gao, Changyou

2018-05-01

Selective adhesion and migration of smooth muscle cells (SMCs) over fibroblasts (FIBs) is required to prevent adventitia fibrosis in vascular regeneration. In this study, a uniform cell-resisting layer of poly(ethylene glycol) (PEG) with a density gradient of azide groups was generated on a substrate by immobilizing two kinds of PEG molecules in a gradient manner. A density gradient of alkynyl-functionalized Val-Ala-Pro-Gly (VAPG) peptides was then prepared on the PEG layer via click chemistry. The VAPG density gradient was characterized by fluorescence imaging, revealing the gradual enhancement of the fluorescent intensity along the substrate direction. The adhesion and mobility of SMCs were selectively enhanced on the VAPG density gradient, leading to directional migration toward the higher peptide density (up to 84%). In contrast, the adhesion and mobility of FIBs were significantly weakened. The net displacement of SMCs also significantly increased compared with that on tissue culture polystyrene (TCPS) and that of FIBs on the gradient. The mitogen-activated protein kinase (MAPK) signaling pathways related to cell migration were studied, showing higher expressions of functional proteins from SMCs on the VAPG-modified surface in a density-dependent manner. For the first time the selective adhesion and directional migration of SMCs over FIBs was achieved by an elaborative design of a gradient surface, leading to a new insight in design of novel vascular regenerative materials. Selective cell adhesion and migration guided by regenerative biomaterials are extremely important for the regeneration of targeted tissues, which can avoid the drawbacks of incorrect and uncontrolled responses of tissue cells to implants. For example, selectivity of smooth muscle cells (SMCs) over fibroblasts (FIBs) is required to prevent adventitia fibrosis in vascular regeneration. Herein we prepare a uniform cell-repelling layer, on which SMCs-selective Val-Ala-Pro-Gly (VAPG) peptides

Noninvasive prenatal diagnosis. Use of density gradient centrifugation, magnetically activated cell sorting and in situ hybridization

DEFF Research Database (Denmark)

Campagnoli, C; Multhaupt, H A; Ludomirski, A

1997-01-01

OBJECTIVE: To develop a noninvasive method suitable for clinical prenatal diagnosis. STUDY DESIGN: Fetal nucleated erythrocytes were separated from peripheral blood of 17 healthy pregnant women using small magnetically activated cell sorting columns (MiniMACS) following density gradient centrifug...

Density effects on tokamak edge turbulence and transport with magnetic X-points

International Nuclear Information System (INIS)

Xu, X.Q.; Cohen, R.H.; Nevins, W.M.; Rognlien, T.D.; Ryutov, D.D.; Umansky, M.V.; Pearlstein, L.D.; Bulmer, R.H.; Russell, D.A.; Myra, J.R.; D'Ippolito, D.A.; Greenwald, M.; Snyder, P.B.; Mahdavi, M.A.

2005-01-01

Results are presented from the 3D electromagnetic turbulence code BOUT, the 2D transport code UEDGE, and theoretical analysis of boundary turbulence and transport in a real divertor-plasma geometry and its relationship to the density limit. Key results include: (1) a transition of the boundary turbulence from resistive X-point to resistive-ballooning as a critical plasma density is exceeded; (2) formation of an X-point MARFE in 2D UEDGE transport simulations for increasing outboard radial transport as found by BOUT for increasing density; (3) identification of convective transport by localized plasma 'blobs' in the SOL at high density during neutral fueling, and decorrelation of turbulence between the midplane and the divertor leg due to strong X-point magnetic shear; (4) a new divertor-leg instability driven at high plasma beta by a radial tilt of the divertor plate. (author)

Radar observations of density gradients, electric fields, and plasma irregularities near polar cap patches in the context of the gradient-drift instability

Science.gov (United States)

Lamarche, Leslie J.; Makarevich, Roman A.

2017-03-01

We present observations of plasma density gradients, electric fields, and small-scale plasma irregularities near a polar cap patch made by the Super Dual Auroral Radar Network radar at Rankin Inlet (RKN) and the northern face of Resolute Bay Incoherent Scatter Radar (RISR-N). RKN echo power and occurrence are analyzed in the context of gradient-drift instability (GDI) theory, with a particular focus on the previously uninvestigated 2-D dependencies on wave propagation, electric field, and gradient vectors, with the latter two quantities evaluated directly from RISR-N measurements. It is shown that higher gradient and electric field components along the wave vector generally lead to the higher observed echo occurrence, which is consistent with the expected higher GDI growth rate, but the relationship with echo power is far less straightforward. The RKN echo power increases monotonically as the predicted linear growth rate approaches zero from negative values but does not continue this trend into positive growth rate values, in contrast with GDI predictions. The observed greater consistency of echo occurrence with GDI predictions suggests that GDI operating in the linear regime can control basic plasma structuring, but measured echo strength may be affected by other processes and factors, such as multistep or nonlinear processes or a shear-driven instability.

High density internal transport barriers for burning plasma operation

Energy Technology Data Exchange (ETDEWEB)

Ridolfini, V Pericoli [Associazione EURATOM-ENEA sulla Fusione, CR Frascati, Rome (Italy); Barbato, E [Associazione EURATOM-ENEA sulla Fusione, CR Frascati, Rome (Italy); Buratti, P [Associazione EURATOM-ENEA sulla Fusione, CR Frascati, Rome (Italy)] (and others)

2005-12-15

A tokamak plasma with internal transport barriers (ITBs) is the best candidate for a steady ITER operation, since the high energy confinement allows working at plasma currents (I{sub p}) lower than the reference scenario. To build and sustain an ITB at the ITER high density ({>=}10{sup 20} m{sup -3}) and largely dominant electron (e{sup -}) heating is not trivial in most existing tokamaks. FTU can instead meet both requests, thanks to its radiofrequency heating systems, lower hybrid (LH, up to 1.9 MW) and electron cyclotron (EC up to 1.2 MW). By the combined use of them, ITBs are obtained up to peak densities n{sub e0} > 1.3 x 10{sup 20} m{sup -3}, with central e{sup -} temperatures T{sub e0} {approx} 5.5 keV, and are sustained for as long as the heating pulse is applied (>35 confinement times, {tau}{sub E}). At n{sub e0} {approx} 0.8 x 10{sup 20} m{sup -3} T{sub e0} can be larger than 11 keV. Almost full current drive (CD) and an overall good steadiness is attained within about one {tau}{sub E}, 20 times faster than the ohmic current relaxation time. The ITB extends over a central region with an almost flat or slightly reversed q profile and q{sub min} {approx} 1.3 that is fully sustained by off-axis lower hybrid current drive. Consequent to this is the beneficial good alignment of the bootstrap current, generated by the ITB large pressure gradients, with the LH driven current. Reflectometry shows a clear change in the turbulence close to the ITB radius, consistent with the reduced e{sup -} transport. Ions (i{sup +}) are significantly heated via collisions, but thermal equilibrium with electrons cannot be attained since the e{sup -}-i{sup +} equipartition time is always 4-5 times longer than {tau}{sub E}. No degradation of the overall ion transport, rather a reduction of the i{sup +} heat diffusivity, is observed inside the ITB. The global confinement has been improved up to 1.6 times over the scaling predictions. The ITB radius can be controlled by adjusting the

EFFECTIVENESS OF DOUBLE WASH SWIM-UP VERSUS DOUBLE DENSITY GRADIENT SWIM-UP TECHNIQUE OF SPERM PREPARATION IN IN VITRO FERTILISATION

Directory of Open Access Journals (Sweden)

Srinivas Sangisapu

2017-10-01

Full Text Available BACKGROUND Recovery of optimum number of good quality of spermatozoa is an important component of In Vitro Fertilisation (IVF. This is achieved by sperm preparation methods involving separation and recovery of capacitated sperms. Double Wash Swim-up (DWSU and Double Density Gradient Swim-up (DDGSU are two most accepted methods. Cochrane systematic review (2007 finds no clear benefit of one method over the other in Intrauterine Insemination (IUI. Systematic review on effectiveness of these preparations in IVF is lacking. Effectiveness is generally assessed in terms recovery rates of the sperms. Capability of successful fertilisation of good quality oocytes should ideally be the functional endpoint for evaluating effectiveness of sperm preparation methods. The aim of the study is to1. Compare the successful fertilisation rates of oocytes inseminated by semen preparation of Double Wash Swim-up (DWSU vis-a-vis by Double Density Gradient Swim-up (DDGSU method. 2. Evaluate the effectiveness of fertilisation of oocytes by Double Wash Swim-up method (DWSU vis-a-vis Double Density Gradient Swim-up (DDGSU method. MATERIALS AND METHODS A retrospective cohort study was conducted on infertile couples undergoing IVF from June 2014 to June 2017 at an ART Centre of a tertiary care hospital. The male partners were normozoospermic and female partners were normoresponsive to controlled ovarian stimulation and oocyte retrieval. RESULTS 70 male partners were subjected to double wash swim-up and 64 underwent double density gradient swim-up preparation. 1296 good quality oocytes were retrieved in their respective female partners. 452 (61% out of 742 oocytes were successfully fertilised after insemination by semen prepared by DWSU method. 378 (68% oocytes out of 554 were fertilised by insemination with semen prepared by DDGSU method. There seems to be strong association (RR=1.12 of fertilisation success with oocytes exposed to semen prepared by Double Density Gradient

Experimental study of electron temperature gradient influence on impurity turbulent transport in fusion plasmas

International Nuclear Information System (INIS)

Villegas, D.

2010-01-01

Understanding impurity transport is a key to an optimal regime for a future fusion device. In this thesis, the theoretical and experimental influence of the electron temperature gradient R/L Te on heavy impurity transport is analyzed both in Tore Supra and ASDEX Upgrade. The electron temperature profile is modified locally by heating the plasma with little ECRH power deposited at two different radii. Experimental results have been obtained with the impurity transport code (ITC) which has been completed with a genetic algorithm allowing to determine the transport coefficient profiles with more accuracy. Transport coefficient profiles obtained by a quasilinear gyrokinetic code named QuaLiKiz are consistent with the experimental ones despite experimental uncertainties on gradients. In the core dominated by electron modes, the lower R/L Te the lower the nickel diffusion coefficient. The latter tends linearly to the neoclassical level when the instability threshold is approached. The experimental threshold is in agreement with the one computed by QuaLiKiz. Further out, where the plasma is dominated by ITG, which are independent of R/L Te , both experimental and simulated results show no modification in the diffusion coefficient profile. Furthermore, the convection velocity profile is not modified. This is attributed to a very small contribution of the thermodiffusion (1/Z dependence) in the total convection. On ASDEX, the preliminary results, very different from the Tore Supra ones, show a internal transport barrier for impurities located at the same radius as the strong ECRH power deposit. (author) [fr

Carrier-Mediated Transport of Nicotine Across the Inner Blood-Retinal Barrier: Involvement of a Novel Organic Cation Transporter Driven by an Outward H(+) Gradient.

Science.gov (United States)

Tega, Yuma; Kubo, Yoshiyuki; Yuzurihara, Chihiro; Akanuma, Shin-Ichi; Hosoya, Ken-Ichi

2015-09-01

The present study was carried out to investigate the blood-to-retina transport of nicotine across the inner blood-retinal barrier (BRB). Using the in vivo vascular injection method, the blood-to-retina influx clearance of nicotine across the BRB was determined as 131 μL/(min?g retina), which is much higher than that of a nonpermeable paracellular marker, and blood-to-retina transport of nicotine was inhibited by organic cations such as pyrilamine and verapamil. The nicotine uptake by a conditionally immortalized rat retinal capillary endothelial cell line (TR-iBRB2 cells), an in vitro model of the inner BRB, exhibited time, temperature, and concentration dependence with a Km of 492 μM. These results suggest the involvement of a carrier-mediated transport process in nicotine transport in the inner BRB. The nicotine uptake by TR-iBRB2 cells was stimulated by an outwardly directed H(+) gradient, and the uptake was significantly inhibited by bulky and hydrophobic cationic drugs, whereas inhibitors of organic cation transporters did not show inhibitory effect. These results suggest that the novel organic cation transport system driven by an outwardly directed H(+) gradient is involved in the blood-to-retina transport of nicotine across the inner BRB. © 2015 Wiley Periodicals, Inc. and the American Pharmacists Association.

Critical temperature gradient and critical current density in thin films of a type I superconductor

Energy Technology Data Exchange (ETDEWEB)

Heubener, R P

1968-12-16

Measurements of the critical temperature gradient and the critical current density in superconducting lead films in a transverse magnetic field indicate that the critical current flows predominantly along the surface of the films and that the critical surface currents contribute only very little to the Lorentz force on a fluxoid.

Derivation of general analytic gradient expressions for density-fitted post-Hartree-Fock methods: An efficient implementation for the density-fitted second-order Møller–Plesset perturbation theory

Energy Technology Data Exchange (ETDEWEB)

Bozkaya, Uğur, E-mail: ugur.bozkaya@atauni.edu.tr [Department of Chemistry, Atatürk University, Erzurum 25240, Turkey and Department of Chemistry, Middle East Technical University, Ankara 06800 (Turkey)

2014-09-28

General analytic gradient expressions (with the frozen-core approximation) are presented for density-fitted post-HF methods. An efficient implementation of frozen-core analytic gradients for the second-order Møller–Plesset perturbation theory (MP2) with the density-fitting (DF) approximation (applying to both reference and correlation energies), which is denoted as DF-MP2, is reported. The DF-MP2 method is applied to a set of alkanes, conjugated dienes, and noncovalent interaction complexes to compare the computational cost of single point analytic gradients with MP2 with the resolution of the identity approach (RI-MP2) [F. Weigend and M. Häser, Theor. Chem. Acc. 97, 331 (1997); R. A. Distasio, R. P. Steele, Y. M. Rhee, Y. Shao, and M. Head-Gordon, J. Comput. Chem. 28, 839 (2007)]. In the RI-MP2 method, the DF approach is used only for the correlation energy. Our results demonstrate that the DF-MP2 method substantially accelerate the RI-MP2 method for analytic gradient computations due to the reduced input/output (I/O) time. Because in the DF-MP2 method the DF approach is used for both reference and correlation energies, the storage of 4-index electron repulsion integrals (ERIs) are avoided, 3-index ERI tensors are employed instead. Further, as in case of integrals, our gradient equation is completely avoid construction or storage of the 4-index two-particle density matrix (TPDM), instead we use 2- and 3-index TPDMs. Hence, the I/O bottleneck of a gradient computation is significantly overcome. Therefore, the cost of the generalized-Fock matrix (GFM), TPDM, solution of Z-vector equations, the back transformation of TPDM, and integral derivatives are substantially reduced when the DF approach is used for the entire energy expression. Further application results show that the DF approach introduce negligible errors for closed-shell reaction energies and equilibrium bond lengths.

The isotope density inverse problem in multigroup neutron transport

International Nuclear Information System (INIS)

Zazula, J.M.

1981-01-01

The inverse problem for stationary multigroup anisotropic neutron transport is discussed in order to search for isotope densities in multielement medium. The spatial- and angular-integrated form of neutron transport equation, in terms of the flux in a group - density of an element spatial correlation, leads to a set of integral functionals for the densities weighted by the group fluxes. Some methods of approximation to make the problem uniquently solvable are proposed. Particularly P 0 angular flux information and the spherically-symetrical geometry of an infinite medium are considered. The numerical calculation using this method related to sooner evaluated direct problem data gives promising agreement with primary densities. This approach would be the basis for further application in an elemental analysis of a medium, using an isotopic neutron source and a moving, energy-dependent neutron detector. (author)

Comparisons of theoretically predicted transport from ion temperature gradient instabilities to L-mode tokamak experiments

International Nuclear Information System (INIS)

Kotschenreuther, M.; Wong, H.V.; Lyster, P.L.; Berk, H.L.; Denton, R.; Miner, W.H.; Valanju, P.

1991-12-01

The theoretical transport from kinetic micro-instabilities driven by ion temperature gradients is a sheared slab is compared to experimentally inferred transport in L-mode tokamaks. Low noise gyrokinetic simulation techniques are used to obtain the ion thermal transport coefficient X. This X is much smaller than in experiments, and so cannot explain L-mode confinement. Previous predictions based on fluid models gave much greater X than experiments. Linear and nonlinear comparisons with the fluid model show that it greatly overestimates transport for experimental parameters. In addition, disagreements among previous analytic and simulation calculations of X in the fluid model are reconciled

Nonlinear neoclassical transport in toroidal edge plasmas

International Nuclear Information System (INIS)

Fueloep, T.; Helander, P.

2001-01-01

In conventional neoclassical theory, the density and temperature gradients are not allowed to be as steep as frequently observed in the tokamak edge. In this paper the theory of neoclassical transport in a collisional, impure plasma is extended to allow for steeper profiles than normally assumed. The dynamics of highly charged impurity ions then becomes nonlinear, which affects the transport of all species. As earlier found in the banana regime, when the bulk plasma gradients are large the impurity ions undergo a poloidal redistribution, which reduces their parallel friction with the bulk ions and suppresses the neoclassical ion particle flux. The neoclassical confinement is thus improved in regions with large radial gradients. When the plasma is collisional and the gradients are large, the impurities accumulate on the inboard side of the torus

Chemical bond as a test of density-gradient expansions for kinetic and exchange energies

International Nuclear Information System (INIS)

Perdew, J.P.; Levy, M.; Painter, G.S.; Wei, S.; Lagowski, J.B.

1988-01-01

Errors in kinetic and exchange contributions to the molecular bonding energy are assessed for approximate density functionals by reference to near-exact Hartree-Fock values. From the molecular calculations of Allan et al. and of Lee and Ghosh, it is demonstrated that the density-gradient expansion does not accurately describe the noninteracting kinetic contribution to the bonding energy, even when this expansion is carried to fourth order and applied in its spin-density-functional form to accurate Hartree-Fock densities. In a related study, it is demonstrated that the overbinding of molecules such as N 2 and F 2 , which occurs in the local-spin-density (LSD) approximation for the exchange-correlation energy, is not attributable to errors in the self-consistent LSD densities. Contrary to expectations based upon the Gunnarsson-Jones nodality argument, it is found that the LSD approximation for the exchange energy can seriously overbind a molecule even when bonding does not create additional nodes in the occupied valence orbitals. LSD and exact values for the exchange contribution to the bonding energy are displayed and discussed for several molecules

Relationship between particle and heat transport in JT-60U plasmas with internal transport barrier

International Nuclear Information System (INIS)

Takenaga, Hidenobu; Higashijima, S.; Oyama, N.

2003-01-01

The relationship between particle and heat transport in an internal transport barrier (ITB) has been systematically investigated in reversed shear (RS) and high β p ELMy H-mode plasmas in JT-60U. No helium and carbon accumulation inside the ITB is observed even with ion heat transport reduced to a neoclassical level. On the other hand, the heavy impurity argon is accumulated inside the ITB. The argon density profile estimated from the soft x-ray profile is more peaked, by a factor of 2-4 in the RS plasma and of 1.6 in the high β p mode plasma, than the electron density profile. The helium diffusivity (D He ) and the ion thermal diffusivity (χ i ) are at an anomalous level in the high β p mode plasma, where D He and χ i are higher by a factor of 5-10 than the neoclassical value. In the RS plasma, D He is reduced from the anomalous to the neoclassical level, together with χ i . The carbon and argon density profiles calculated using the transport coefficients reduced to the neoclassical level only in the ITB are more peaked than the measured profiles, even when χ i is reduced to the neoclassical level. Argon exhaust from the inside of the ITB is demonstrated by applying ECH in the high β p mode plasma, where both electron and argon density profiles become flatter. The reduction of the neoclassical inward velocity for argon due to the reduction of density gradient is consistent with the experimental observation. In the RS plasma, the density gradient is not decreased by ECH and argon is not exhausted. These results suggest the importance of density control to suppress heavy impurity accumulation. (author)

Impurity transport model for the normal confinement and high density H-mode discharges in Wendelstein 7-AS

International Nuclear Information System (INIS)

Ida, K; Burhenn, R; McCormick, K; Pasch, E; Yamada, H; Yoshinuma, M; Inagaki, S; Murakami, S; Osakabe, M; Liang, Y; Brakel, R; Ehmler, H; Giannone, L; Grigull, P; Knauer, J P; Maassberg, H; Weller, A

2003-01-01

An impurity transport model based on diffusivity and the radial convective velocity is proposed as a first approach to explain the differences in the time evolution of Al XII (0.776 nm), Al XI (55 nm) and Al X (33.3 nm) lines following Al-injection by laser blow-off between normal confinement discharges and high density H-mode (HDH) discharges. Both discharge types are in the collisional regime for impurities (central electron temperature is 0.4 keV and central density exceeds 10 20 m -3 ). In this model, the radial convective velocity is assumed to be determined by the radial electric field, as derived from the pressure gradient. The diffusivity coefficient is chosen to be constant in the plasma core but is significantly larger in the edge region, where it counteracts the high local values of the inward convective velocity. Under these conditions, the faster decay of aluminium in HDH discharges can be explained by the smaller negative electric field in the bulk plasma, and correspondingly smaller inward convective velocity, due to flattening of the density profiles

Sociodemographic Factors, Population Density, and Bicycling for Transportation in the United States.

Science.gov (United States)

Nehme, Eileen K; Pérez, Adriana; Ranjit, Nalini; Amick, Benjamin C; Kohl, Harold W

2016-01-01

Transportation bicycling is a behavior with demonstrated health benefits. Population-representative studies of transportation bicycling in United States are lacking. This study examined associations between sociodemographic factors, population density, and transportation bicycling and described transportation bicyclists by trip purposes, using a US-representative sample. This cross-sectional study used 2009 National Household Travel Survey datasets. Associations among study variables were assessed using weighted multivariable logistic regression. On a typical day in 2009, 1% of Americans older than 5 years of age reported a transportation bicycling trip. Transportation cycling was inversely associated with age and directly with being male, with being white, and with population density (≥ 10,000 vs transportation. Twenty-one percent of transportation bicyclists reported trips to work, whereas 67% reported trips to social or other activities. Transportation bicycling in the United States is associated with sociodemographic characteristics and population density. Bicycles are used for a variety of trip purposes, which has implications for transportation bicycling research based on commuter data and for developing interventions to promote this behavior.

A continuum self organized critically model of turbulent heat transport in tokamaks

Energy Technology Data Exchange (ETDEWEB)

Tangri, V; Das, A; Kaw, P; Singh, R [Institute for Plasma Research, Gandhinagar (India)

2003-09-01

Based on the now well known and experimentally observed critical gradient length (R/L{sub Te} = RT/{nabla}T) in tokamaks, we present a continuum one dimensional model for explaining self organized heat transport in tokamaks. Key parameters of this model include a novel hysteresis parameter which ensures that the switch of heat transport coefficient {chi} upwards and downwards takes place at two different values of R/L{sub Te}. Extensive numerical simulations of this model reproduce many features of present day tokamaks such as submarginal temperature profiles, intermittent transport events, 1/f scaling of the frequency spectra, propagating fronts, etc. This model utilises a minimal set of phenomenological parameters, which may be determined from experiments and/or simulations. Analytical and physical understanding of the observed features has also been attempted. (author)

Cultivo de células mesenquimais do sangue de cordão umbilical com e sem uso do gradiente de densidade Ficoll-Paque Blood mesenchymal stem cell culture from the umbilical cord with and without Ficoll-Paque density gradient method

Directory of Open Access Journals (Sweden)

Rosa Sayoko Kawasaki-Oyama

2008-03-01

Ficoll-Paque gradient density method (d=1.077g/ml. METHODS: Ten samples of the umbilical cord blood obtained from full-term deliveries were submitted to two different procedures of mesenchymal stem cell culture: a Method without the Ficoll-Paque density gradient, which concentrates all nucleated cells; b Method with the Ficoll-Paque density gradient, which selects only low-density mononuclear cells. Cells were initially plated into 25 cm² cultures flasks at a density of 1x10(7 nucleated cells/cm² and 1x10(6 mononuclear cells/cm². RESULTS: It was obtained 2-13x10(7 (median = 2.35x10(7 nucleated cells/cm² by the method without the Ficoll-Paque gradient density, and 3.7-15.7x10(6 (median = 7.2x10(6 mononuclear cells/cm² by the method with the Ficoll-Paque gradient density. In all cultures adherent cells were observed 24 hours after being cultured. Cells presented fibroblastoid and epithelioid morphology. In most of the cultures, cell proliferation occurred in the first week, but after the second week only some cultures - derived from the method without the Ficoll-Paque gradient density - maintained the growth rate reaching confluence. Those cultures were submitted to trypsinization with 0.25% trypsin/EDTA solution and cultured for two to three months. CONCLUSION: In the samples analyzed, cell separation and mesenchymal stem cell culture techniques from human umbilical cord blood by the method without the Ficoll-Paque density gradient was more efficient than the method with the Ficoll-Paque density gradient.

Vertical pneumatic conveying in dilute and dense-phase flows: experimental study of the influence of particle density and diameter on fluid dynamic behavior

Directory of Open Access Journals (Sweden)

Narimatsu C.P.

2001-01-01

Full Text Available In this work, the effects of particle size and density on the fluid dynamic behavior of vertical gas-solid transport of Group D particles in a 53.4 mm diameter transport tube were studied. For the conditions tested, the experimental curves of pressure gradient versus air velocity presented a minimum pressure gradient point, which is associated with a change in the flow regime from dense to dilute phase. The increases in particle size from 1.00 to 3.68 mm and in density from 935 to 2500 kg/m³ caused an increase in pressure gradient for the dense-phase transport region, but were not relevant in dilute transport. The transition velocity between dense and dilute flow (Umin also increased with increasing particle density and diameter. An empirical equation was fitted for predicting transition air velocity for the transport of glass spheres. Additional experiments, covering a wider range of conditions and particles properties, are still needed to allow the fitting of a generalized equation for prediction of Umin.

High Upward Fluxes of Formic Acid from a Boreal Forest Canopy

Science.gov (United States)

Schobesberger, Siegfried; Lopez-Hilifiker, Felipe D.; Taipale, Ditte; Millet, Dylan B.; D'Ambro, Emma L.; Rantala, Pekka; Mammarella, Ivan; Zhou, Putian; Wolfe, Glenn M.; Lee, Ben H.;

Crust-mantle density distribution in the eastern Qinghai-Tibet Plateau revealed by satellite-derived gravity gradients

Science.gov (United States)

LI, Honglei; Fang, Jian; Braitenberg, Carla; Wang, Xinsheng

2015-04-01

As the highest, largest and most active plateau on Earth, the Qinghai-Tibet Plateau has a complex crust-mantle structure, especially in its eastern part. In response to the subduction of the lithospheric mantle of the Indian plate, large-scale crustal motion occurs in this area. Despite the many previous studies, geodynamic processes at depth remain unclear. Knowledge of crust and upper mantle density distribution allows a better definition of the deeper geological structure and thus provides critically needed information for understanding of the underlying geodynamic processes. With an unprecedented precision of 1-2 mGal and a spatial resolution better than 100 km, GOCE (Gravity field and steady-state Ocean Circulation Explorer) mission products can be used to constrain the crust-mantle density distribution. Here we used GOCE gravitational gradients at an altitude of 10km after reducing the effects of terrain, sediment thickness variations, and Moho undulations to image the density structures of eastern Tibet up to 200 km depths. We inverted the residual satellite gravitational gradients using a least square approach. The initial density model for the inversion is based on seismic velocities from the tomography. The model is composed of rectangular blocks, having a uniform density, with widths of about 100 km and variable thickness and depths. The thickness of the rectangular cells changes from10 to 60km in accordance with the seismic model. Our results reveal some large-scale, structurally controlled density variations at depths. The lithospheric root defined by higher-density contrast features from southwest to northeast, with shallowing in the central part: base of lithosphere reaches a depth of180 km, less than 100km, and 200 km underneath the Lhasa, Songpan-Ganzi, and Ordos crustal blocks, respectively. However, these depth values only represent a first-order parameterization because they depend on model discretization inherited from the original seismic

Effects of density gradients and fluctuations at the plasma edge on ECEI measurements at ASDEX Upgrade

NARCIS (Netherlands)

Vanovac, B.; Wolfrum, E.; Denk, S. S.; Mink, F.; Laggner, F. M.; Birkenmeier, G.; Willensdorfer, M.; Viezzer, E.; Hoelzl, M.; Freethy, S. J.; Dunne, M. G.; Lessig, A.; Luhmann, N. C.; ASDEX Upgrade team,; EUROfusion MST1 Team,

2018-01-01

Electron cyclotron emission imaging (ECEI) provides measurements of electron temperature (T-e) and its fluctuations (delta T-e). However, when measuring at the plasma edge, in the steep gradient region, radiation transport effects must be taken into account. It is shown that due to these effects,

Impact of large scale flows on turbulent transport

Energy Technology Data Exchange (ETDEWEB)

Sarazin, Y [Association Euratom-CEA, CEA/DSM/DRFC centre de Cadarache, 13108 St-Paul-Lez-Durance (France); Grandgirard, V [Association Euratom-CEA, CEA/DSM/DRFC centre de Cadarache, 13108 St-Paul-Lez-Durance (France); Dif-Pradalier, G [Association Euratom-CEA, CEA/DSM/DRFC centre de Cadarache, 13108 St-Paul-Lez-Durance (France); Fleurence, E [Association Euratom-CEA, CEA/DSM/DRFC centre de Cadarache, 13108 St-Paul-Lez-Durance (France); Garbet, X [Association Euratom-CEA, CEA/DSM/DRFC centre de Cadarache, 13108 St-Paul-Lez-Durance (France); Ghendrih, Ph [Association Euratom-CEA, CEA/DSM/DRFC centre de Cadarache, 13108 St-Paul-Lez-Durance (France); Bertrand, P [LPMIA-Universite Henri Poincare Nancy I, Boulevard des Aiguillettes BP239, 54506 Vandoe uvre-les-Nancy (France); Besse, N [LPMIA-Universite Henri Poincare Nancy I, Boulevard des Aiguillettes BP239, 54506 Vandoe uvre-les-Nancy (France); Crouseilles, N [IRMA, UMR 7501 CNRS/Universite Louis Pasteur, 7 rue Rene Descartes, 67084 Strasbourg (France); Sonnendruecker, E [IRMA, UMR 7501 CNRS/Universite Louis Pasteur, 7 rue Rene Descartes, 67084 Strasbourg (France); Latu, G [LSIIT, UMR 7005 CNRS/Universite Louis Pasteur, Bd Sebastien Brant BP10413, 67412 Illkirch (France); Violard, E [LSIIT, UMR 7005 CNRS/Universite Louis Pasteur, Bd Sebastien Brant BP10413, 67412 Illkirch (France)

2006-12-15

The impact of large scale flows on turbulent transport in magnetized plasmas is explored by means of various kinetic models. Zonal flows are found to lead to a non-linear upshift of turbulent transport in a 3D kinetic model for interchange turbulence. Such a transition is absent from fluid simulations, performed with the same numerical tool, which also predict a much larger transport. The discrepancy cannot be explained by zonal flows only, despite they being overdamped in fluids. Indeed, some difference remains, although reduced, when they are artificially suppressed. Zonal flows are also reported to trigger transport barriers in a 4D drift-kinetic model for slab ion temperature gradient (ITG) turbulence. The density gradient acts as a source drive for zonal flows, while their curvature back stabilizes the turbulence. Finally, 5D simulations of toroidal ITG modes with the global and full-f GYSELA code require the equilibrium density function to depend on the motion invariants only. If not, the generated strong mean flows can completely quench turbulent transport.

Impact of large scale flows on turbulent transport

International Nuclear Information System (INIS)

Sarazin, Y; Grandgirard, V; Dif-Pradalier, G; Fleurence, E; Garbet, X; Ghendrih, Ph; Bertrand, P; Besse, N; Crouseilles, N; Sonnendruecker, E; Latu, G; Violard, E

2006-01-01

The impact of large scale flows on turbulent transport in magnetized plasmas is explored by means of various kinetic models. Zonal flows are found to lead to a non-linear upshift of turbulent transport in a 3D kinetic model for interchange turbulence. Such a transition is absent from fluid simulations, performed with the same numerical tool, which also predict a much larger transport. The discrepancy cannot be explained by zonal flows only, despite they being overdamped in fluids. Indeed, some difference remains, although reduced, when they are artificially suppressed. Zonal flows are also reported to trigger transport barriers in a 4D drift-kinetic model for slab ion temperature gradient (ITG) turbulence. The density gradient acts as a source drive for zonal flows, while their curvature back stabilizes the turbulence. Finally, 5D simulations of toroidal ITG modes with the global and full-f GYSELA code require the equilibrium density function to depend on the motion invariants only. If not, the generated strong mean flows can completely quench turbulent transport

Dual-Polarization Radar Observations of Upward Lightning-Producing Storms

Science.gov (United States)

Lueck, R.; Helsdon, J. H.; Warner, T.

2013-12-01

The Upward Lightning Triggering Study (UPLIGHTS) seeks to determine how upward lightning, which originates from the tips of tall objects, is triggered by nearby flash activity. As a component of this study we analyze standard and dual-polarization weather radar data. The Correlation Coefficient (CC) in particular can be used to identify and quantify the melting layer associated with storms that produce upward lightning. It has been proposed that positive charge generation due to aggregate shedding at the melting layer results in a positive charge region just above the cloud base. This positive charge region may serve as a positive potential well favorable for negative leader propagation, which initiate upward positive leaders from tall objects. We characterize the horizontal coverage, thickness and height of the melting layer in addition to cloud base heights when upward lightning occurs to determine trends and possible threshold criteria relating to upward lightning production. Furthermore, we characterize storm type and morphology using relevant schemes as well as precipitation type using the Hydrometer Classification Algorithm (HCA) for upward lightning-producing storms. Ice-phase hydrometeors have been shown to be a significant factor in thunderstorm electrification. Only a small fraction of storms produce upward lightning, so null cases will be examined and compared as well.

A new interferometry-based electron density fluctuation diagnostic on Alcator C-Moda)

Science.gov (United States)

Kasten, C. P.; Irby, J. H.; Murray, R.; White, A. E.; Pace, D. C.

2012-10-01

The two-color interferometry diagnostic on the Alcator C-Mod tokamak has been upgraded to measure fluctuations in the electron density and density gradient for turbulence and transport studies. Diagnostic features and capabilities are described. In differential mode, fast phase demodulation electronics detect the relative phase change between ten adjacent, radially-separated (ΔR = 1.2 cm, adjustable), vertical-viewing chords, which allows for measurement of the line-integrated electron density gradient. The system can be configured to detect the absolute phase shift of each chord by comparison to a local oscillator, measuring the line-integrated density. Each chord is sensitive to density fluctuations with kR < 20.3 cm-1 and is digitized at up to 10 MS/s, resolving aspects of ion temperature gradient-driven modes and other long-wavelength turbulence. Data from C-Mod discharges is presented, including observations of the quasi-coherent mode in enhanced D-alpha H-mode plasmas and the weakly coherent mode in I-mode.

Electron density measurements during ion beam transport on Gamble II

International Nuclear Information System (INIS)

Weber, B.V.; Hinshelwood, D.D.; Neri, J.M.; Ottinger, P.F.; Rose, D.V.; Stephanakis, S.J.; Young, F.C.

1999-01-01

High-sensitivity laser interferometry was used to measure the electron density created when an intense proton beam (100 kA, 1 MeV, 50 ns) from the Gamble II generator was transported through low-pressure gas as part of a project investigating Self-Pinched Transport (SPT) of intense ion beams. This measurement is non-perturbing and sufficiently quantitative to allow benchmarking of codes (particularly IPROP) used to model beam-gas interaction and ion-beam transport. Very high phase sensitivity is required for this measurement. For example, a 100-kA, 1-MeV, 10-cm-radius proton beam with uniform current density has a line-integrated proton density equal to n b L = 3 x 10 13 cm -2 . An equal electron line-density, n e L = n b L, (expected for transport in vacuum) will be detected as a phase shift of the 1.064 microm laser beam of only 0.05degree, or an optical path change of 1.4 x 10 -4 waves (about the size of a hydrogen atom). The time-history of the line-integrated electron density, measured across a diameter of the transport chamber at 43 cm from the input aperture, starts with the proton arrival time and decays differently depending on the gas pressure. The gas conditions included vacuum (10 -4 Torr air), 30 to 220 mTorr He, and 1 Torr air. The measured densities vary by three orders of magnitude, from 10 13 to 10 16 cm -2 for the range of gas pressures investigated. In vacuum, the measured electron densities indicate only co-moving electrons (n e L approximately n b L). In He, when the gas pressure is sufficient for ionization by beam particles and SPT is observed, n e L increases to about 10 n b L. At even higher pressures where electrons contribute to ionization, even higher electron densities are observed with an ionization fraction of about 2%. The diagnostic technique as used on the SPT experiment will be described and a summary of the results will be given. The measurements are in reasonable agreement with theoretical predictions from the IPROP code

Isolating peripheral lymphocytes by density gradient centrifugation and magnetic cell sorting.

Science.gov (United States)

Brosseron, Frederic; Marcus, Katrin; May, Caroline

2015-01-01

Combining density gradient centrifugation with magnetic cell sorting provides a powerful tool to isolate blood cells with high reproducibility, yield, and purity. It also allows for subsequent separation of multiple cell types, resulting in the possibility to analyze different purified fractions from one donor's sample. The centrifugation step divides whole blood into peripheral blood mononuclear cells (PBMC), erythrocytes, and platelet-rich plasma. In the following, lymphocyte subtypes can be consecutively isolated from the PBMC fraction. This chapter describes enrichment of erythrocytes, CD14-positive monocytes and CD3-positive T lymphocytes. Alternatively, other cell types can be targeted by using magnetic beads specific for the desired subpopulation.

A reduced model for ion temperature gradient turbulent transport in helical plasmas

International Nuclear Information System (INIS)

Nunami, M.; Watanabe, T.-H.; Sugama, H.

2013-07-01

A novel reduced model for ion temperature gradient (ITG) turbulent transport in helical plasmas is presented. The model enables one to predict nonlinear gyrokinetic simulation results from linear gyrokinetic analyses. It is shown from nonlinear gyrokinetic simulations of the ITG turbulence in helical plasmas that the transport coefficient can be expressed as a function of the turbulent fluctuation level and the averaged zonal flow amplitude. Then, the reduced model for the turbulent ion heat diffusivity is derived by representing the nonlinear turbulent fluctuations and zonal flow amplitude in terms of the linear growth rate of the ITG instability and the linear response of the zonal flow potentials. It is confirmed that the reduced transport model results are in good agreement with those from nonlinear gyrokinetic simulations for high ion temperature plasmas in the Large Helical Device. (author)

Density functional theory calculations of charge transport properties ...

Indian Academy of Sciences (India)

ZIRAN CHEN

2017-08-04

Aug 4, 2017 ... properties of 'plate-like' coronene topological structures ... Keywords. Organic semiconductors; density functional theory; charge carrier mobility; ambipolar transport; ..... nology Department of Sichuan Province (Grant Number.

Improving Rydberg Excitations within Time-Dependent Density Functional Theory with Generalized Gradient Approximations: The Exchange-Enhancement-for-Large-Gradient Scheme.

Science.gov (United States)

Li, Shaohong L; Truhlar, Donald G

2015-07-14

Time-dependent density functional theory (TDDFT) with conventional local and hybrid functionals such as the local and hybrid generalized gradient approximations (GGA) seriously underestimates the excitation energies of Rydberg states, which limits its usefulness for applications such as spectroscopy and photochemistry. We present here a scheme that modifies the exchange-enhancement factor to improve GGA functionals for Rydberg excitations within the TDDFT framework while retaining their accuracy for valence excitations and for the thermochemical energetics calculated by ground-state density functional theory. The scheme is applied to a popular hybrid GGA functional and tested on data sets of valence and Rydberg excitations and atomization energies, and the results are encouraging. The scheme is simple and flexible. It can be used to correct existing functionals, and it can also be used as a strategy for the development of new functionals.

Condition of damping of anomalous radial transport, determined by ordered convective electron dynamics

International Nuclear Information System (INIS)

Maslov, V.I.; Barchuk, S.V.; Lapshin, V.I.; Volkov, E.D.; Melentsov, Yu.V.

2006-01-01

It is shown, that at development of instability due to a radial gradient of density in the crossed electric and magnetic fields in nuclear fusion installations ordering convective cells can be excited. It provides anomalous particle transport. The spatial structures of these convective cells have been constructed. The radial dimensions of these convective cells depend on their amplitudes and on a radial gradient of density. The convective-diffusion equation for radial dynamics of the electrons has been derived. At the certain value of the universal controlling parameter, the convective cell excitation and the anomalous radial transport are suppressed. (author)

Vitality of oligozoospermic semen samples is improved by both swim-up and density gradient centrifugation before cryopreservation.

Science.gov (United States)

Counsel, Madeleine; Bellinge, Rhys; Burton, Peter

2004-05-01

To ascertain whether washing sperm from oligozoospermic and normozoospermic samples before cryopreservation improves post-thaw vitality. Normozoospermic (n = 18) and oligozoospermic (n = 16) samples were divided into three aliquots. The first aliquot remained untreated and the second and third aliquots were subjected to the swim-up and discontinuous density gradient sperm washing techniques respectively. Vitality staining was performed, samples mixed with cryopreservation media and frozen. Spermatozoa were thawed, stained, and vitality quantified and expressed as the percentage of live spermatozoa present. Post-thaw vitality in untreated aliquots from normozoospermic samples (24.9% +/- 2.3; mean +/- SEM) was significantly higher (unpaired t-tests; P vitality was significantly higher after swim-up in normozoospermic samples (35.6% +/- 2.1; P vitality in oligozoospermic (22.4% +/- 1.0; P vitality in cryopreserved oligozoospermic samples was improved by both the swim-up and density gradient centrifugation washing techniques prior to freezing.

Charge Energy Transport in Hopping Systems with Rapidly Decreasing Density of States

Science.gov (United States)

Mendels, Dan; Organic Electronics Group Technion Team

2014-03-01

An accurate description of the carrier hopping topology in the energy domain of hopping systems incorporating a rapidly decreasing density of states and the subsequent energetic position of these systems' so called effective conduction band is crucial for rationalizing and quantifying these systems' thermo-electric properties, doping related phenomena and carrier gradient effects such as the emergence of the General Einstein Relation under degenerate conditions. Additionally, as will be shown, the 'mobile' carriers propagating through the system can have excess energies reaching 0.3eV above the system quasi-Fermi energy. Hence, since these mobile carriers are most prone to reach systems interfaces and interact with oppositely charged carriers, their excess energy should be considered in determining the efficiencies of energy dependent processes such as carrier recombination and exciton dissociation. In light of the stated motivations, a comprehensive numerical and analytical study of the topology of hopping in the energetic density of such systems (i.e. the statistics regarding which energy values carriers visit most and in what manner) was implemented and the main statistical features of the hopping process that determine the position in energy of the system's effective conduction band were distilled. The obtained results also help shed light on yet to be elucidated discrepancies between predictions given by the widely employed transport energy concept and Monte Carlo simulations.

Changes in home range sizes and population densities of carnivore species along the natural to urban habitat gradient

Czech Academy of Sciences Publication Activity Database

Šálek, Martin; Drahníková, L.; Tkadlec, Emil

2015-01-01

Roč. 45, č. 1 (2015), s. 1-14 ISSN 0305-1838 Institutional support: RVO:68081766 Keywords : Carnivores * home range size * natural–urban gradient * population density * review Subject RIV: EG - Zoology Impact factor: 4.116, year: 2015

Influence of coupling phenomena on the transport through compacted clays

Energy Technology Data Exchange (ETDEWEB)

Rosanne, M.; Koudina, N.; Adler, P.M. [IPGP, Paris (France); Tevissen, E. [ANDRA, Dept. Etude-Experimentation et Calcul, Chatenay Malabry (France)

2001-07-01

Our principal motivation was to study the influence of the coupling phenomena on transport through compacted clays. Coupled transports may occur when a pressure gradient {nabla}P, and electrical field E and a concentration gradient {nabla}C interact. These three gradients induce three fluxes. A flow is generated characterized by the seepage velocity U; a solute flux J{sub L} and a current density I are generated. Close to equilibrium, when the gradients are not to large, the problem is linear and the fluxes are linear functions of the gradients. A first series of experiments was performed with argillite to determine the diagonal properties, i.e., permeability, conductivity, and diffusion coefficient. In a second series of experiments, the voltage resulting from an imposed concentration gradient between two reservoirs separated by a clay sample was systematically measured; this corresponds to the coefficient L{sub 13}. (orig.)

Density Dependence of Particle Transport in ECH Plasmas of the TJ-II Stellarator

Energy Technology Data Exchange (ETDEWEB)

Vargas, V. I.; Lopez-Bruna, D.; Guasp, J.; Herranz, J.; Estrada, T.; Medina, F.; Ochando, M.A.; Velasco, J.L.; Reynolds, J.M.; Ferreira, J.A.; Tafalla, D.; Castejon, F.; Salas, A.

2009-05-21

We present the experimental dependence of particle transport on average density in electron cyclotron heated (ECH) hydrogen plasmas of the TJ-II stellarator. The results are based on: (I) electron density and temperature data from Thomson Scattering and reflectometry diagnostics; (II) a transport model that reproduces the particle density profiles in steady state; and (III) Eirene, a code for neutrals transport that calculates the particle source in the plasma from the particle confinement time and the appropriate geometry of the machine/plasma. After estimating an effective particle diffusivity and the particle confinement time, a threshold density separating qualitatively and quantitatively different plasma transport regimes is found. The poor confinement times found below the threshold are coincident with the presence of ECH-induced fast electron losses and a positive radial electric field all over the plasma. (Author) 40 refs.

Behavior of the particle transport coefficients near the density limit in MTX

International Nuclear Information System (INIS)

Marinak, M.M.

1993-04-01

The perturbed particle transport coefficients were determined for a range of plasma conditions in the Alcator C tokamak, a component of the Microwave Tokamak Experiment (MTX), from analysis of density perturbations created in gas modulation experiments. Density measurements from a 15 chord far-infrared interferometer were sufficiently detailed to allow radial profiles of the transport coefficients to be resolved. Gas modulation experiments were carried out on plasmas over a range of relatively low currents and a wide variety of line-averaged densities, including values near the Greenwald density limit. With this technique the perturbed diffusion coefficient D and the perturbed convection velocity V can be determined simultaneously. Measured profiles of D rise toward the outside of the plasma column in a manner generally similar to those determined previously for χ e,HP from sawtooth heat pulse propagation. Values of D are typically smaller than those of χ e,HP given for the same line-averaged densities by a factor of 2-5. Diffusion coefficients from a series of discharges at constant current showed little variation with density through most of the saturated ohmic confinement regime. At the Greenwald density limit threshold a dramatic increase occurred in both the perturbed convective and diffusive transport coefficients in the outer region of the plasma. The increases were most pronounced at the outermost range of the radii where coefficients were determined (r/a = 0.8), but were apparent over a region which extended well into the plasma interior. Density profiles maintained a similar shape near the density limit, congruous with the similar behavior of the transport coefficients. No dramatic deterioration was evident in the global energy confinement

Measurements of density profile evolution during the stably-stratified filling of an open enclosure

International Nuclear Information System (INIS)

Tarawneh, Constantine M.; Homan, K.O.

2008-01-01

The stably-stratified filling of an open enclosure produces an interfacial gradient layer which is transported through the enclosure with the bulk flow. The evolution of this interfacial layer is strongly time-dependent and is driven by the nature of the interaction between the internal gravity waves and the inlet-driven interfacial shear. Measurements of density profile evolution have been completed for a rectangular enclosure with a single corner inlet and density variation produced by saline concentration. This system serves as a mass transfer analog to large-scale, thermally-stratified energy storage devices, preserving dynamic similitude in a laboratory-scale system. The experiments covered jet Reynolds numbers of 200-2200 and Froude numbers of 0.06-0.6 in an enclosure with a width 23 times the jet inlet height. The density profiles are seen to be strongly asymmetric and exhibit growth rates significantly different than due to simple one-dimensional molecular diffusion. In addition, shadowgraph and hydrogen bubble visualizations of the density and velocity fields in the gradient layer show the persistence of complex multi-dimensional flow structure even at relatively late stages of the filling process when the gradient layer has been transported well away from the enclosure inlet. The evolution of the vertical density profile has been compared quantitatively to a quasi one-dimensional model based upon empirical diffusivity coefficients

Resistance scaling for composite fermions in the presence of a density gradient

International Nuclear Information System (INIS)

Stormer, H. L.; Tsui, Daniel Chee; Pan, Wei; West, Ken W.; Baldwin, K. W.; Pfeiffer, Loren N.

2006-01-01

The magnetoresistance, R xx , at even-denominator fractional fillings, of an ultra high quality two-dimensional electron system at T ∼ 35 mK is observed to be strictly linear in magnetic field, B. While at 35 mK R xx is dominated by the integer and fractional quantum Hall states, at T ≅ 1.2 K an almost perfect linear relationship between R xx and B emerges over the whole magnetic field range except for spikes at the integer quantum Hall states. This linear R xx cannot be understood within the Composite Fermion model, but can be explained through the existence of a density gradient in our sample

Effects of fueling profiles on plasma transport

International Nuclear Information System (INIS)

Houlberg, W.A.; Mense, A.T.; Attenberger, S.E.; Milora, S.L.

1977-01-01

The effects of cold particle fueling profiles on particle and energy transport in an ignition sized tokamak plasma are investigated in this study with a one-dimensional, multifluid transport model. A density gradient driven trapped particle microinstability model for plasma transport is used to demonstrate potential effects of fueling profiles on ignition requirements. Important criteria for the development of improved transport models under the conditions of shallow particle fueling profiles are outlined. A discrete pellet fueling model indicates that large fluctuations in density and temperature may occur in the outer regions of the plasma with large, shallowly penetrating pellets, but fluctuations in the pressure profile are small. The hot central core of the plasma remains unaffected by the large fluctuations near the plasma edge

Nonlinear transport in semiconducting polymers at high carrier densities.

Science.gov (United States)

Yuen, Jonathan D; Menon, Reghu; Coates, Nelson E; Namdas, Ebinazar B; Cho, Shinuk; Hannahs, Scott T; Moses, Daniel; Heeger, Alan J

2009-07-01

Conducting and semiconducting polymers are important materials in the development of printed, flexible, large-area electronics such as flat-panel displays and photovoltaic cells. There has been rapid progress in developing conjugated polymers with high transport mobility required for high-performance field-effect transistors (FETs), beginning with mobilities around 10(-4) cm(2) V(-1) s(-1) to a recent report of 1 cm(2) V(-1) s(-1) for poly(2,5-bis(3-tetradecylthiophen-2-yl)thieno[3,2-b]thiophene) (PBTTT). Here, the electrical properties of PBTTT are studied at high charge densities both as the semiconductor layer in FETs and in electrochemically doped films to determine the transport mechanism. We show that data obtained using a wide range of parameters (temperature, gate-induced carrier density, source-drain voltage and doping level) scale onto the universal curve predicted for transport in the Luttinger liquid description of the one-dimensional 'metal'.

Sediment transport via needle ice: a new method for diffusive transport on laboratory-scale hillslopes

Science.gov (United States)

Sweeney, K. E.; Roering, J. J.; Rempel, A. W.

2012-12-01

Convex hilltops formed by diffusive sediment transport are a fundamental feature of soil-mantled landscapes worldwide. Additionally, the competition and interaction between hillslopes and valleys control basic topographic metrics, such as relief, drainage density, and breaks in slope-area scaling. Despite recent progress in erosive landscape experiments, no published work has explored the competition of hillslope diffusion and channel advection experimentally. Here, we present preliminary findings on the plausibility of needle ice driven frost creep as a mechanism for laboratory hillslope transport of wet sediment. In nature, needle ice is a diurnal form of ice segregation, whereby liquid water held in sediment pore space is driven upward toward a near-surface freezing front by a temperature-controlled liquid pressure gradient. As needles grow perpendicular to the surface, sediment is incorporated in the growing needle ice by temperature perturbations and associated downward shifts in the freezing front. Sediment then moves downslope due to melting or sublimation of the ice needles. We constructed a slope of saturated sediment in a freezer to constrain the temperature, grain size, and soil moisture limits on laboratory needle ice growth and sediment transport. Surficial sediment transport is measured during experimentation by tracking the movement of colored grains. Additionally, at the end of each run we measure depth-dependent sediment transport by taking slices of the experimental slope and observing the displacement of buried columns of colored grains. In agreement with past work, we find that with temperatures just below freezing, soil moisture above 35%, and silt-sized sediment, the moisture migration induced by freezing releases enough latent heat to maintain the location of the freezing front and encourage needle ice growth. Our experiments demonstrate that the amount of sediment incorporated during needle growth, i.e., the transport efficiency, can be

Density control problems in large stellarators with neoclassical transport

International Nuclear Information System (INIS)

Maassberg, H.; Beidler, C.D.; Simmet, E.E.

1999-01-01

With respect to the particle flux, the off-diagonal term in the neoclassical transport matrix becomes crucial in the stellarator long-mean-free-path regime. Central heating with peaked temperature profiles can make an active density profile control by central particle refuelling mandatory. The neoclassical particle confinement can significantly exceed the energy confinement at the outer radii. As a consequence, the required central refuelling may be larger than the neoclassical particle fluxes at outer radii leading to the loss of the global density control. Radiative losses as well as additional 'anomalous' electron heat diffusivities further exacerbate this problem. In addition to the analytical formulation of the neoclassical link of particle and energy fluxes, simplified model simulations as well as time-dependent ASTRA code simulations are described. In particular, the 'low-' and 'high-mirror' W7-X configurations are compared. For the W7-X 'high-mirror' configuration especially, the appearance of the neoclassical particle transport barrier is predicted at higher densities. (author)

EUROMECH colloquium 377. Stability and control of shear flows with strong temperature or density gradients. Book of abstracts

International Nuclear Information System (INIS)

1998-10-01

The topics discussed comprise the onset of instability in heated free jets and jets with density gradients, flow past heated/cooled boundaries, atmospheric shear flow, and mathematical modeling of laminar-turbulent transition phenomena. Three contributions have been input to INIS. (P.A.)

Evaluation of upward migration around a deep injection well

International Nuclear Information System (INIS)

Chia, Yeeping; Chiu, J.

1994-01-01

The long-term containment of injected wastes in the deep subsurface is expected to be achieved under suitable geologic and hydrologic conditions and by the use of competent engineering practices. Field experiences, however, indicate that waste containment may be affected by hydrologic conduits around the injection well. To assess the potential effects of these conduits, upward migration of injected waste is examined through the use of numerical models under various conditions. Test results indicate that without any preferential hydrologic conduits, most of the injected waste moves laterally in the injection interval, whereas only a small amount of waste migrates upward into the containment interval. When vertical fractures in the disturbed zone or defects in the cement seal around the wellbore exist, the contaminant can move rapidly upward along these conduits to an overlying aquifer, from which it migrates in the lateral direction. The contamination of the overlying aquifer that results from the upward migration of injected waste through these conduits cannot be impeded by a thick, low-permeability containment interval. However, when permeable interbeds exist within the containment interval, a significant portion of the waste migrating upward can be diverted laterally before reaching the overlying aquifer. The front of built-up pressure can reach the aquifer or permeable interbed immediately overlying the injection interval through the preferential hydrologic conduits shortly after the injection starts, but it cannot move farther upward because of pressure dissipation in the permeable formation. This study suggests that the injected waste has the potential to migrate upward into overlying formations through preferential migration conduits around the wellbore

Upward counterfactual thinking and depression: A meta-analysis.

Science.gov (United States)

Broomhall, Anne Gene; Phillips, Wendy J; Hine, Donald W; Loi, Natasha M

2017-07-01

This meta-analysis examined the strength of association between upward counterfactual thinking and depressive symptoms. Forty-two effect sizes from a pooled sample of 13,168 respondents produced a weighted average effect size of r=.26, pdesign (cross-sectional versus longitudinal). Significant effect size heterogeneity was observed across sample types, methods of assessing upward counterfactual thinking, and types of depression scale. Significant positive effects were found in studies that employed samples of bereaved individuals, older adults, terminally ill patients, or university students, but not adolescent mothers or mixed samples. Both number-based and Likert-based upward counterfactual thinking assessments produced significant positive effects, with the latter generating a larger effect. All depression scales produced significant positive effects, except for the Psychiatric Epidemiology Research Interview. Research and theoretical implications are discussed in relation to cognitive theories of depression and the functional theory of upward counterfactual thinking, and important gaps in the extant research literature are identified. Copyright © 2017 Elsevier Ltd. All rights reserved.

Activity-dependent formation of a vesicular inhibitory amino acid transporter gradient in the superior olivary complex of NMRI mice.

Science.gov (United States)

Ebbers, Lena; Weber, Maren; Nothwang, Hans Gerd

2017-10-26

In the mammalian superior olivary complex (SOC), synaptic inhibition contributes to the processing of binaural sound cues important for sound localization. Previous analyses demonstrated a tonotopic gradient for postsynaptic proteins mediating inhibitory neurotransmission in the lateral superior olive (LSO), a major nucleus of the SOC. To probe, whether a presynaptic molecular gradient exists as well, we investigated immunoreactivity against the vesicular inhibitory amino acid transporter (VIAAT) in the mouse auditory brainstem. Immunoreactivity against VIAAT revealed a gradient in the LSO and the superior paraolivary nucleus (SPN) of NMRI mice, with high expression in the lateral, low frequency processing limb and low expression in the medial, high frequency processing limb of both nuclei. This orientation is opposite to the previously reported gradient of glycine receptors in the LSO. Other nuclei of the SOC showed a uniform distribution of VIAAT-immunoreactivity. No gradient was observed for the glycine transporter GlyT2 and the neuronal protein NeuN. Formation of the VIAAT gradient was developmentally regulated and occurred around hearing-onset between postnatal days 8 and 16. Congenital deaf Claudin14 -/- mice bred on an NMRI background showed a uniform VIAAT-immunoreactivity in the LSO, whereas cochlear ablation in NMRI mice after hearing-onset did not affect the gradient. Additional analysis of C57Bl6/J, 129/SvJ and CBA/J mice revealed a strain-specific formation of the gradient. Our results identify an activity-regulated gradient of VIAAT in the SOC of NRMI mice. Its absence in other mouse strains adds a novel layer of strain-specific features in the auditory system, i.e. tonotopic organization of molecular gradients. This calls for caution when comparing data from different mouse strains frequently used in studies involving transgenic animals. The presence of strain-specific differences offers the possibility of genetic mapping to identify molecular

The tempered one-sided stable density: a universal model for hydrological transport?

International Nuclear Information System (INIS)

Cvetkovic, Vladimir

2011-01-01

A generalized distribution for the water residence time in hydrological transport is proposed in the form of the tempered one-sided stable (TOSS) density. It is shown that limiting cases of the TOSS distribution recover virtually all distributions that have been considered in the literature for hydrological transport, from plug flow to flow reactor, the advection-dispersion model, and the gamma and Levy densities. The stable property of TOSS is particularly important, enabling a seamless transition between a time-domain random walk, and the Lagrangian (trajectory) approach along hydrological transport pathways.

Vorticity, backscatter and counter-gradient transport predictions using two-level simulation of turbulent flows

Science.gov (United States)

Ranjan, R.; Menon, S.

2018-04-01

The two-level simulation (TLS) method evolves both the large-and the small-scale fields in a two-scale approach and has shown good predictive capabilities in both isotropic and wall-bounded high Reynolds number (Re) turbulent flows in the past. Sensitivity and ability of this modelling approach to predict fundamental features (such as backscatter, counter-gradient turbulent transport, small-scale vorticity, etc.) seen in high Re turbulent flows is assessed here by using two direct numerical simulation (DNS) datasets corresponding to a forced isotropic turbulence at Taylor's microscale-based Reynolds number Reλ ≈ 433 and a fully developed turbulent flow in a periodic channel at friction Reynolds number Reτ ≈ 1000. It is shown that TLS captures the dynamics of local co-/counter-gradient transport and backscatter at the requisite scales of interest. These observations are further confirmed through a posteriori investigation of the flow in a periodic channel at Reτ = 2000. The results reveal that the TLS method can capture both the large- and the small-scale flow physics in a consistent manner, and at a reduced overall cost when compared to the estimated DNS or wall-resolved LES cost.

Phase distribution phenomena in upward cocurrent bubbly flows. A critical review of the experimental and theoretical works

International Nuclear Information System (INIS)

Grossetete, C.

1992-09-01

The most important and challenging problems in two-phase bubbly flow today are related to the physical understanding and the modeling of multidimensional phenomena such as the distribution of phases in space. We present here a critical review of the available experimental and theoretical studies in gas-liquid adiabatic and non-reactive upward bubbly flows which have been carried out to define and improve the physical models needed to close the three-dimensional two-fluid model equations. It appears that: so far, the axial development of two-phase upward bubbly flows has not been handled thoroughly. Little is known about the way the pressure gradient as well as the gas-liquid mixing conditions affect the distribution of phases, the problems related to the closing of the two-fluid model equations are far from being solved. The physical models proposed seem often to be too much complex considering how little we know about the mechanisms involved, there are still very few multidimensional numerical models whose results have been compared with experimental data on bubbly flows. The boundary conditions introduced in the codes as well as the sensitivity of the results to the parameters of the codes are never precisely stated. To bridge some of those gaps, we propose to perform an experimental and numerical study of the axial development of two-phase air-water upward bubbly flows in vertical pipes

Formation of an internal transport barrier in the ohmic H-mode in the TUMAN-3M tokamak

International Nuclear Information System (INIS)

Andrejko, M.V.; Askinazi, L.G.; Golant, V.E.; Zhubr, N.A.; Kornev, V.A.; Krikunov, S.V.; Lebedev, S.V.; Levin, L.S.; Razdobarin, G.T.; Rozhdestvensky, V.V.; Smirnov, A.I.; Tukachinsky, A.S.; Yaroshevich, S.P.

2000-01-01

In experiments on studying the ohmic H-mode in the TUMAN-3M tokamak, it is found that, in high-current (I p ∼ 120-170 kA) discharges, a region with high electron-temperature and density gradients is formed in the plasma core. In this case, the energy confinement time τ E attains 9-18 ms, which is nearly twice as large as that predicted by the ELM-free ITER-93H scaling. This is evidence that the internal transport barrier in a plasma can exist without auxiliary heating. Calculations of the effective thermal diffusivity by the ASTRA transport code demonstrate a strong suppression of heat transport in the region where the temperature and density gradients are high

Plasma membrane temperature gradients and multiple cell permeabilization induced by low peak power density femtosecond lasers

Directory of Open Access Journals (Sweden)

Allen L. Garner

2016-03-01

Full Text Available Calculations indicate that selectively heating the extracellular media induces membrane temperature gradients that combine with electric fields and a temperature-induced reduction in the electropermeabilization threshold to potentially facilitate exogenous molecular delivery. Experiments by a wide-field, pulsed femtosecond laser with peak power density far below typical single cell optical delivery systems confirmed this hypothesis. Operating this laser in continuous wave mode at the same average power permeabilized many fewer cells, suggesting that bulk heating alone is insufficient and temperature gradients are crucial for permeabilization. This work suggests promising opportunities for a high throughput, low cost, contactless method for laser mediated exogenous molecule delivery without the complex optics of typical single cell optoinjection, for potential integration into microscope imaging and microfluidic systems.

Processing of semen by density gradient centrifugation selects spermatozoa with longer telomeres for assisted reproduction techniques.

Science.gov (United States)

Yang, Qingling; Zhang, Nan; Zhao, Feifei; Zhao, Wanli; Dai, Shanjun; Liu, Jinhao; Bukhari, Ihtisham; Xin, Hang; Niu, Wenbing; Sun, Yingpu

2015-07-01

The ends of eukaryotic chromosomes contain specialized chromatin structures called telomeres, the length of which plays a key role in early human embryonic development. Although the effect of sperm preparation techniques on major sperm characteristics, such as concentration, motility and morphology have been previously documented, the possible status of telomere length and its relation with sperm preparation techniques is not well-known for humans. The aim of this study was to investigate the role of density gradient centrifugation in the selection of spermatozoa with longer telomeres for use in assisted reproduction techniques in 105 samples before and after sperm processing. After density gradient centrifugation, the average telomere length of the sperm was significantly longer (6.51 ± 2.54 versus 5.16 ± 2.29, P average motile sperm rate was significantly higher (77.9 ± 11.8 versus 44.6 ± 11.2, P average DNA fragmentation rate was significantly lower (11.1 ± 5.9 versus 25.9 ± 12.9, P sperm count (rs = 0.58; P sperm with longer telomeres. Copyright © 2015 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

Current density fluctuations and ambipolarity of transport

International Nuclear Information System (INIS)

Shen, W.; Dexter, R.N.; Prager, S.C.

1991-10-01

The fluctuation in the plasma current density is measured in the MIST reversed field pinch experiment. Such fluctuations, and the measured radial profile of the k spectrum of magnetic fluctuations, supports the view and that low frequency fluctuations (f r >) demonstrates that radial particle transport from particle motion parallel to a fluctuating magnetic field is ambipolar over the full frequency range

Magneto-optical imaging of transport current densities in superconductors

International Nuclear Information System (INIS)

Crabtree, G.W.; Welp, U.; Gunter, D.O.; Zhong, W.; Balachandran, U.; Haldar, P.; Sokolowski, R.S.; Vlasko-Vlasov, V.K.; Nikitenko, V.I.

1995-01-01

Direct imaging of the paths of transport currents in superconductors creates many new possibilities for exploring the basic features of vortex pinning mechanisms and for improving the performance of superconducting materials. A technique for imaging the path and magnitude of the transport current density flowing in superconductors is described. Results are given for a 37-filament BSCCO 2223 powder-in-tube wire, showing a highly inhomogeneous current path within the filaments

Analytic energy gradients for orbital-optimized MP3 and MP2.5 with the density-fitting approximation: An efficient implementation.

Science.gov (United States)

Bozkaya, Uğur

2018-03-15

Efficient implementations of analytic gradients for the orbital-optimized MP3 and MP2.5 and their standard versions with the density-fitting approximation, which are denoted as DF-MP3, DF-MP2.5, DF-OMP3, and DF-OMP2.5, are presented. The DF-MP3, DF-MP2.5, DF-OMP3, and DF-OMP2.5 methods are applied to a set of alkanes and noncovalent interaction complexes to compare the computational cost with the conventional MP3, MP2.5, OMP3, and OMP2.5. Our results demonstrate that density-fitted perturbation theory (DF-MP) methods considered substantially reduce the computational cost compared to conventional MP methods. The efficiency of our DF-MP methods arise from the reduced input/output (I/O) time and the acceleration of gradient related terms, such as computations of particle density and generalized Fock matrices (PDMs and GFM), solution of the Z-vector equation, back-transformations of PDMs and GFM, and evaluation of analytic gradients in the atomic orbital basis. Further, application results show that errors introduced by the DF approach are negligible. Mean absolute errors for bond lengths of a molecular set, with the cc-pCVQZ basis set, is 0.0001-0.0002 Å. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

M*/L gradients driven by IMF variation: large impact on dynamical stellar mass estimates

Science.gov (United States)

Bernardi, M.; Sheth, R. K.; Dominguez-Sanchez, H.; Fischer, J.-L.; Chae, K.-H.; Huertas-Company, M.; Shankar, F.

2018-06-01

Within a galaxy the stellar mass-to-light ratio ϒ* is not constant. Recent studies of spatially resolved kinematics of nearby early-type galaxies suggest that allowing for a variable initial mass function (IMF) returns significantly larger ϒ* gradients than if the IMF is held fixed. We show that ignoring such IMF-driven ϒ* gradients can have dramatic effect on dynamical (M_*^dyn), though stellar population (M_*^SP) based estimates of early-type galaxy stellar masses are also affected. This is because M_*^dyn is usually calibrated using the velocity dispersion measured in the central regions (e.g. Re/8) where stars are expected to dominate the mass (i.e. the dark matter fraction is small). On the other hand, M_*^SP is often computed from larger apertures (e.g. using a mean ϒ* estimated from colours). If ϒ* is greater in the central regions, then ignoring the gradient can overestimate M_*^dyn by as much as a factor of two for the most massive galaxies. Large ϒ*-gradients have four main consequences: First, M_*^dyn cannot be estimated independently of stellar population synthesis models. Secondly, if there is a lower limit to ϒ* and gradients are unknown, then requiring M_*^dyn=M_*^SP constrains them. Thirdly, if gradients are stronger in more massive galaxies, then accounting for this reduces the slope of the correlation between M_*^dyn/M_*^SP of a galaxy with its velocity dispersion. In particular, IMF-driven gradients bring M_*^dyn and M_*^SP into agreement, not by shifting M_*^SP upwards by invoking constant bottom-heavy IMFs, as advocated by a number of recent studies, but by revising M_*^dyn estimates in the literature downwards. Fourthly, accounting for ϒ* gradients changes the high-mass slope of the stellar mass function φ (M_*^dyn), and reduces the associated stellar mass density. These conclusions potentially impact estimates of the need for feedback and adiabatic contraction, so our results highlight the importance of measuring ϒ* gradients in

Edge transport barrier formation in compact helical system

International Nuclear Information System (INIS)

Okamura, S; Minami, T; Oishi, T; Suzuki, C; Ida, K; Isobe, M; Yoshimura, Y; Nagaoka, K; Toi, K; Fujisawa, A; Akiyama, T; Iguchi, H; Ikeda, R; Kado, S; Matsuoka, K; Matsushita, H; Nakamura, K; Nakano, H; Nishimura, S; Nishiura, M; Ohshima, S; Shimizu, A; Takagi, S; Takahashi, C; Takeuchi, M; Yoshinuma, M

2004-01-01

The edge transport barrier (ETB) for particle transport is formed in the neutral beam (NB) heated hydrogen discharges in compact helical system (CHS). The transition to the ETB formation and the back transition are controlled by the heating power. The existence of the heating power threshold is confirmed and it is roughly proportional to the density. The Hα emission signal shows a clear drop at the transition (the timescale of signal decrease is ∼1 ms for the high heating power case). The ETB formation continues for the full duration of NB injection (100 ms) with a moderate level of radiation power loss. Local density profile measurement shows increase of the edge density and the movement of the density gradient region towards the edge

Edge transport barrier formation and ELM phenomenology in the W7-AS stellarator

International Nuclear Information System (INIS)

Grigull, P.; Hirsch, M.; Baldzuhn, J.; Ehmler, H.; Gadelmeier, F.; Giannone, L.; Hartfuss, H.-J.; Hildebrandt, D.; Jaenicke, R.; Kisslinger, J.; Koenig, R.; McCormick, K.; Wagner, F.; Weller, A.; Wendland, Ch.

2001-01-01

In NBI discharges with density ramps in W7-AS, the quiescent H-mode is restricted to the same ranges of the edge rotational transform as in ECRH discharges and occurs above threshold densities ≥10 20 m -3 which increase with heating power. Higher power needs higher density for stabilization. The approach to the quiescent H-mode often occurs, with increasing density and decreasing power flow through the edge, from grassy through dithering states to bursts of ELMs and, in a few cases, quasi-periodic ELMs. This goes parallel with increasing radial gradients of the plasma pressure and E-field at the edge. Higher heating power reduces in particular the T i gradients and hence the E-field gradients, which effect can be compensated by higher density. The correlations found are fairly consistent when an ExB flow shear decorrelation of the turbulent transport is assumed

An analysis of the gradient-induced electric fields and current densities in human models when situated in a hybrid MRI-LINAC system

International Nuclear Information System (INIS)

Liu, Limei; Trakic, Adnan; Sanchez-Lopez, Hector; Liu, Feng; Crozier, Stuart

2014-01-01

MRI-LINAC is a new image-guided radiotherapy treatment system that combines magnetic resonance imaging (MRI) with a linear accelerator (LINAC) in a single unit. One drawback is that the pulsing of the split gradient coils of the system induces an electric field and currents in the patient which need to be predicted and evaluated for patient safety. In this novel numerical study the in situ electric fields and associated current densities were evaluated inside tissue-accurate male and female human voxel models when a number of different split-geometry gradient coils were operated. The body models were located in the MRI-LINAC system along the axial and radial directions in three different body positions. Each model had a region of interest (ROI) suitable for image-guided radiotherapy. The simulation results show that the amplitudes and distributions of the field and current density induced by different split x-gradient coils were similar with one another in the ROI of the body model, but varied outside of the region. The fields and current densities induced by a split classic coil with the surface unconnected showed the largest deviation from those given by the conventional non-split coils. Another finding indicated that the distributions of the peak current densities varied when the body position, orientation or gender changed, while the peak electric fields mainly occurred in the skin and fat tissues. (paper)

Density gradient localization of vanadate- and NO-3-sensitive ATPase from sterile cultures of Spirodela polyrrhiza (L. Schleiden

Directory of Open Access Journals (Sweden)

Józef Buczek

2014-01-01

Full Text Available The present work deals with the separation and some characteristics of ATPase activities bound with plant membanes prepared from sterile cultures of Spirodela polyrrhiza. The membrane-bound ATPases were separated on sucrose gradients and distinguished by membrane density and sensitivity to several inhibitors. The results showed that N0-3-sensitive ATPase activity associated with the tonoplast was localized at a sucrose density between 1.095-1.117 g•cm-3. The vanadate-sensitive ATPase activity bound with the plasma membrane showed a density between 1.127-1.151 g•cm-3. Both ATPases were insensitive to azide and oligomycin and were separable from markers for mitochondria.

Study of homogeneous bubble nucleation in liquid carbon dioxide by a hybrid approach combining molecular dynamics simulation and density gradient theory

Science.gov (United States)

Langenbach, K.; Heilig, M.; Horsch, M.; Hasse, H.

2018-03-01

A new method for predicting homogeneous bubble nucleation rates of pure compounds from vapor-liquid equilibrium (VLE) data is presented. It combines molecular dynamics simulation on the one side with density gradient theory using an equation of state (EOS) on the other. The new method is applied here to predict bubble nucleation rates in metastable liquid carbon dioxide (CO2). The molecular model of CO2 is taken from previous work of our group. PC-SAFT is used as an EOS. The consistency between the molecular model and the EOS is achieved by adjusting the PC-SAFT parameters to VLE data obtained from the molecular model. The influence parameter of density gradient theory is fitted to the surface tension of the molecular model. Massively parallel molecular dynamics simulations are performed close to the spinodal to compute bubble nucleation rates. From these simulations, the kinetic prefactor of the hybrid nucleation theory is estimated, whereas the nucleation barrier is calculated from density gradient theory. This enables the extrapolation of molecular simulation data to the whole metastable range including technically relevant densities. The results are tested against available experimental data and found to be in good agreement. The new method does not suffer from typical deficiencies of classical nucleation theory concerning the thermodynamic barrier at the spinodal and the bubble size dependence of surface tension, which is typically neglected in classical nucleation theory. In addition, the density in the center of critical bubbles and their surface tension is determined as a function of their radius. The usual linear Tolman correction to the capillarity approximation is found to be invalid.

Study of homogeneous bubble nucleation in liquid carbon dioxide by a hybrid approach combining molecular dynamics simulation and density gradient theory.

Science.gov (United States)

Langenbach, K; Heilig, M; Horsch, M; Hasse, H

2018-03-28

A new method for predicting homogeneous bubble nucleation rates of pure compounds from vapor-liquid equilibrium (VLE) data is presented. It combines molecular dynamics simulation on the one side with density gradient theory using an equation of state (EOS) on the other. The new method is applied here to predict bubble nucleation rates in metastable liquid carbon dioxide (CO 2 ). The molecular model of CO 2 is taken from previous work of our group. PC-SAFT is used as an EOS. The consistency between the molecular model and the EOS is achieved by adjusting the PC-SAFT parameters to VLE data obtained from the molecular model. The influence parameter of density gradient theory is fitted to the surface tension of the molecular model. Massively parallel molecular dynamics simulations are performed close to the spinodal to compute bubble nucleation rates. From these simulations, the kinetic prefactor of the hybrid nucleation theory is estimated, whereas the nucleation barrier is calculated from density gradient theory. This enables the extrapolation of molecular simulation data to the whole metastable range including technically relevant densities. The results are tested against available experimental data and found to be in good agreement. The new method does not suffer from typical deficiencies of classical nucleation theory concerning the thermodynamic barrier at the spinodal and the bubble size dependence of surface tension, which is typically neglected in classical nucleation theory. In addition, the density in the center of critical bubbles and their surface tension is determined as a function of their radius. The usual linear Tolman correction to the capillarity approximation is found to be invalid.

Edge transport and its interconnection with main chamber recycling in ASDEX upgrade

International Nuclear Information System (INIS)

Kallenbach, A.; Dux, R.; Gafert, J.

2003-01-01

Edge profiles of electron temperature and density are measured in ASDEX Upgrade with high spatial resolution of 2-3 mm with Thomson scattering. In the region of the edge transport barrier in ELMy H-mode, the gradient lengths of T e and n e are found closely coupled, with the temperature profile twice as steep as the density profile corresponding to η e ∼ 2. The edge density in the region of the barrier foot is closely coupled to the main chamber recycling, with no strong dependence on other parameters. In contrast the density rise from the outer barrier foot to the pedestal exhibits pronounced dependence on plasma current and shaping, indicating quite different mechanisms determining the absolute density and its gradient. (author)

Arbuscular mycorrhizal fungal community composition affected by original elevation rather than translocation along an altitudinal gradient on the Qinghai-Tibet Plateau

Science.gov (United States)

Yang, Wei; Zheng, Yong; Gao, Cheng; Duan, Ji-Chuang; Wang, Shi-Ping; Guo, Liang-Dong

2016-11-01

Elucidating arbuscular mycorrhizal (AM) fungal responses to elevation changes is critical to improve understanding of microbial function in ecosystems under global asymmetrical climate change scenarios. Here we examined AM fungal community in a two-year reciprocal translocation of vegetation-intact soil blocks along an altitudinal gradient (3,200 m to 3,800 m) in an alpine meadow on the Qinghai-Tibet Plateau. AM fungal spore density was significantly higher at lower elevation than at higher elevation regardless of translocation, except that this parameter was significantly increased by upward translocation from original 3,200 m to 3,400 m and 3,600 m. Seventy-three operational taxonomic units (OTUs) of AM fungi were recovered using 454-pyrosequencing of 18S rDNA sequences at a 97% sequence similarity. Original elevation, downward translocation and upward translocation did not significantly affect AM fungal OTU richness. However, with increasing altitude the OTU richness of Acaulosporaceae and Ambisporaceae increased, but the OTU richness of Gigasporaceae and Glomeraceae decreased generally. The AM fungal community composition was significantly structured by original elevation but not by downward translocation and upward translocation. Our findings highlight that compared with the short-term reciprocal translocation, original elevation is a stronger determinant in shaping AM fungal community in the Qinghai-Tibet alpine meadow.

Monotonous and oscillation instability of mechanical equilibrium of isothermal three-components mixture with zero-gradient density

International Nuclear Information System (INIS)

Zhavrin, Yu.I.; Kosov, V.N.; Kul'zhanov, D.U.; Karataev, K.K.

2000-01-01

Presence of two types of instabilities of mechanical equilibrium of a mixture experimentally is shown at an isothermal diffusion of multicomponent system with zero gradient of density/ Theoretically is proved, that partial Rayleigh numbers R 1 , R 2 having different signs, there are two areas with monotonous (R 1 2 < by 0) instability. The experimental data confirm presence of these areas and satisfactory are described by the represented theory. (author)

Regularized Regression and Density Estimation based on Optimal Transport

KAUST Repository

Burger, M.; Franek, M.; Schonlieb, C.-B.

2012-01-01

for estimating densities and for preserving edges in the case of total variation regularization. In order to compute solutions of the variational problems, a regularized optimal transport problem needs to be solved, for which we discuss several formulations

Lithosphere density structure beneath the eastern margin of the Tibetan Plateau and its surrounding areas derived from GOCE gradients data

Directory of Open Access Journals (Sweden)

Honglei Li

2017-05-01

Full Text Available A three-dimensional density model of the crust and uppermost mantle is determined by the inversion of a set of GOCE gravity and gradients residual anomalies beneath the eastern margin of the Tibetan Plateau and its surrounding areas. In our work, we choose five independent gravity gradients (Txx, Tzz, Txy, Txz, Tyz to perform density inversion. Objective function is given based on Tikhonov regularization theory. Seismic S-wave velocities play the role of initial constraint for the inversion based on a relationship between density and S-wave velocity. Damped Least Square method is used during the inversion. The final density results offer some insights into understanding the underlying geodynamic processes: (1 Low densities in the margin of the Tibet, along with low wave velocity and resistivity results, yield conversions from soft and weak Tibet to the hard and rigid cratons. (2The lowest densities are found in the boundary of the plateau, instead of the whole Tibet indicates that the effects of extrusion stress environment in the margin affect the changes of the substance there. The substances and environments conditioning for the earthquake preparations and strong deformation in this transitional zone. (3 Evident low-D anomaly in the upper and middle crust in the Lasha terrane and Songpan-Ganzi terrane illustrated the eastward sub-ducted of southeastern Tibet, which could be accounts for the frequent volcano and earthquakes there.

Pancreatin-EDTA treatment affects buoyancy of cells in Cohn fraction V protein density gradients without residual effect on cell size.

Science.gov (United States)

Sheridan, J W; Simmons, R J

1983-12-01

The buoyancy of suspension-grown Mastocytoma P815 X-2 cells in albumin-rich Cohn fraction V protein (CFVP) density gradients was found to be affected by prior incubation of the cells in pancreatin-EDTA salt solution. Whereas in pH 5.2 CFVP, pancreatin-EDTA treated cells behaved as if of reduced density when compared with the control 'undigested' group, in pH 7.3 CFVP they behaved as if of increased density. By contrast, pancreatin-EDTA treatment had no effect on the buoyancy of mastocytoma cells in polyvinylpyrrolidone-coated colloidal silica (PVP-CS, Percoll T.M.) density gradients of either pH 5.2 or pH 7.3. As cell size determinations failed to reveal alterations in cell size either as a direct result of pancreatin-EDTA treatment or as a combined consequence of such treatment and exposure to CFVP either with or without centrifugation, a mechanism involving a change in cell density other than during the centrifugation process itself seems unlikely. Binding studies employing 125I-CFVP, although indicating that CFVP bound to cells at 4 degrees, failed to reveal a pancreatin-EDTA treatment-related difference in the avidity of this binding. Although the mechanism of the pancreatin-EDTA-induced buoyancy shift in CFVP remains obscure, the absence of such an effect in PVP-CS suggests that the latter cell separation solution may more accurately be used to determine cell density.

Effect of density on forward and upward smoldering combustion of cellulosic material

Science.gov (United States)

Veronica, Sherly; Putri, R. H.; Fitriani, F.; Ramadhan, M. L.; Riki, M.; Reynaldo, S.; Imran, F. A.; Nugroho, Yulianto S.

2017-03-01

Smoldering is a slow, flameless and the most persistent type of combustion. Wildland fire or ground fire is an example of smoldering combustion which has become one of the most important issue in Indonesia and no effective solution has been found to solve this phenomenon yet. The organic materials contained in peatland can potentially become a flammable fuel with the presence of a trigger for wildland fire. In this experimental work tobacco material was used to study smoldering phenomenon. The relation between material density with temperature distribution and mass loss rate are conducted in the experiment. The transmissivity of the smoke produced by the smoldering combustion will also be analyzed. Experiments are carried out for the material density ranging from 0.12 - 0.2 g/cm3. The result showed that smoldering combustion are affected by density, due to the allowance of airflow and heat propagation. The result showed that material bed with the lowest density of 0.12 g/cm3 has the slowest smoldering velocity and mass loss rate while the material bed with the highest density of 0.2 g/cm3 has the fastest smoldering velocity and mass loss rate. The smoke took a longer period time to reach the bed surface at higher bed density.

Large Eddy Simulations of Compositional Density Currents Flowing Over a Mobile Bed

Science.gov (United States)

Kyrousi, Foteini; Zordan, Jessica; Leonardi, Alessandro; Juez, Carmelo; Zanello, Francesca; Armenio, Vincenzo; Franca, Mário J.

2017-04-01

Density currents are a ubiquitous phenomenon caused by natural events or anthropogenic activities, and play an important role in the global sediment cycle; they are agents of long distance sediment transport in lakes, seas and oceans. Density gradients induced by salinity, temperature differences, or by the presence of suspended material are all possible triggers of a current. Such flows can travel long distances while eroding or depositing bed materials. This can provoke rapid topological changes, which makes the estimation of their transport capacity of prime interest for environmental engineering. Despite their relevance, field data regarding their dynamics is limited due to density currents scattered and unpredictable occurrence in nature. For this reason, laboratory experiments and numerical simulations have been a preferred way to investigate sediment transport processes associated to density currents. The study of entrainment and deposition processes requires detailed data of velocities spatial and temporal distributions in the boundary layer and bed shear stress, which are troublesome to obtain in laboratory. Motivated by this, we present 3D wall-resolved Large Eddy Simulations (LES) of density currents generated by lock-exchange. The currents travel over a smooth flat bed, which includes a section composed by erodible fine sediment susceptible of eroding. Several sediment sizes and initial density gradients are considered. The grid is set to resolve the velocity field within the boundary layer of the current (a tiny fraction of the total height), which in turn allows to obtain predictions of the bed shear stress. The numerical outcomes are compared with experimental data obtained with an analogous laboratory setting. In laboratory experiments salinity was chosen for generating the initial density gradient in order to facilitate the identification of entrained particles, since salt does not hinder the possibility to track suspended particles. Under these

COMPARISON OF GKS CALCULATED CRITICAL ION TEMPERATURE GRADIENTS AND ITG GROWTH RATES TO DIII-D MEASURED GRADIENTS AND DIFFUSIVITIES

International Nuclear Information System (INIS)

BAKER, DR; STAEBLER, GM; PETTY, CC; GREENFIELD, CM; LUCE, TC

2003-01-01

OAK-B135 The gyrokinetic equations predict that various drift type waves or modes can be unstable in a tokamak. For some of these modes, such as the ion temperature gradient (ITG) mode and the electron temperature gradient mode, there exists a critical gradient, above which the mode is unstable. Since the existence of unstable modes can cause increased transport, plasmas which are centrally heated tend to increase in temperature gradient until the modes become unstable. Under some conditions the increased transport can fix the gradient at the critical value. here they present a comparison between the measured ion temperature gradients and the critical gradient as calculated by a gyrokinetic linear stability (GKS) code. They also present the maximum linear growth rate as calculated by this code for comparison to experimentally derived transport coefficients. The results show that for low confinement mode (L-mode) discharges, the measured ion temperature gradient is significantly greater than the GKS calculated critical gradient over a large region of the plasma. This is the same region of the plasma where the ion thermal diffusivity is large. For high confinement mode (H-mode) discharges the ion temperature gradient is closer to the critical gradient, but often still greater than the critical gradient over some region. For the best H-mode discharges, the ion temperature is less than or equal to the critical gradient over the whole plasma. In general they find that the position in the plasma where the ion thermal diffusivity starts to increase rapidly is where the maximum linear growth rate is greater than the E x B shearing rate

On the density limit of Tokamaks

International Nuclear Information System (INIS)

Lehnert, B.

1982-12-01

Under the conditions of so far performed quasi-steady tokamak experiments near the density limit, the plasma pressure gradient in the outer layers of the plasma body becomes mainly determined by the plasma-neutral gas balance. An earlier analysis of ballooning instabilities driven by this gradient in regions of bad curvature has been extended to deduce an explicit stability criterion which determines the density limit. This criterion is closely related to the empirical Murakami limit. At relevant tokamak data, the deduced limit becomes proportional to J(sub)zR(sup)1/2 where J(sub)z is the average current density and R the major plasma radius. It is further found to be independent of the toroidal magnetic field strength and anomalous transport, as well as to be a slow function of the outer layer temperature and the mass number. The deduced stability criterion is consistent with so far performed experiments. Provided that the present analysis can be extrapolated to a wider range of parameter data and be combined with Alcator scaling, conditions near ignition appear to become realizable in small tokamaks by ohmic heating alone. These conditions can be satisfied at relevant magnetic field strengths and plasma currents, by imposing a high plasma current density. (author)

Turbulence and anomalous transport in toroidal plasmas

International Nuclear Information System (INIS)

Nordman, H.

1989-01-01

In present-day Tokamak fusion machines, instabilities and turbulence driven by temperature gradients can have a considerable impact on the confinement qualities. This thesis is mainly devoted to analyzing the nonlinear evolution of these instabilities and the associated turbulent transport. A combined analytical and numerical study of the ion temperature gradient driven turbulence is presented. An analytical expression for the ion thermal conductivity is derived and found to be in good agreement with the simulation results. The scaling properties of chi i are investigated and compared with experimental results. The transport due to the simultaneous presence of a trapped electron mode and an ion temperature gradient mode is analysed. It is found that the coupling of the modes can give rise to inward diffusive fluxes of both particles and energy. The tendency of the system to equilibrate density and temperature scale lengths is compared with recent experimental trends. The nonlinear behaviour of the instabilities is also studied in the context of low dimensional dynamical systems. Here, the relation between the fully nonlinear fluid models and the low dimensional models is discussed. The influence of a high frequency RF-field on the ion temperature gradient driven mode is investigated analytically. The consequences for mode stability and transport are considered. 23 refs

Turbulence and anomalous transport in toroidal plasmas

Energy Technology Data Exchange (ETDEWEB)

Nordman, H

1990-12-31

In present-day Tokamak fusion machines, instabilities and turbulence driven by temperature gradients can have a considerable impact on the confinement qualities. This thesis is mainly devoted to analyzing the nonlinear evolution of these instabilities and the associated turbulent transport. A combined analytical and numerical study of the ion temperature gradient driven turbulence is presented. An analytical expression for the ion thermal conductivity is derived and found to be in good agreement with the simulation results. The scaling properties of chi{sub i} are investigated and compared with experimental results. The transport due to the simultaneous presence of a trapped electron mode and an ion temperature gradient mode is analysed. It is found that the coupling of the modes can give rise to inward diffusive fluxes of both particles and energy. The tendency of the system to equilibrate density and temperature scale lengths is compared with recent experimental trends. The nonlinear behaviour of the instabilities is also studied in the context of low dimensional dynamical systems. Here, the relation between the fully nonlinear fluid models and the low dimensional models is discussed. The influence of a high frequency RF-field on the ion temperature gradient driven mode is investigated analytically. The consequences for mode stability and transport are considered. 23 refs.

Effect of stable-density stratification on counter gradient flux of a homogeneous shear flow

Energy Technology Data Exchange (ETDEWEB)

Lida, Oaki; Nagano, Yasutaka [Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya (Japan). Department of Mechanical Engineering

2007-01-15

We performed direct numerical simulations of homogeneous shear flow under stable-density stratification to study the buoyancy effects on the heat and momentum transfer. These numerical data were compared with those of a turbulent channel flow to investigate the similarity between the near-wall turbulence and the homogeneous shear flow. We also investigated the generation mechanism of the persistent CGFs (counter gradient fluxes) appearing at the higher wavenumbers of the cospectrum, and lasting over a long time without oscillation. Spatially, the persistent CGFs are associated with the longitudinal vortical structure, which is elongated in the streamwise direction and typically observed in both homogeneous shear flow and near-wall turbulence. The CGFs appear at both the top and bottom of this longitudinal vortical structure, and expand horizontally with an increase in the Richardson number. It was found that the production and turbulent-diffusion terms are responsible for the distribution of the Reynolds shear stress including the persistent CGFs. The buoyancy term, combined with the swirling motion of the vortex, contributes to expand the persistent CGF regions and decrease the down gradient fluxes. (author)

A comparison of density functional theory and coupled cluster methods for the calculation of electric dipole polarizability gradients of methane

DEFF Research Database (Denmark)

Paidarová, Ivana; Sauer, Stephan P. A.

2012-01-01

We have compared the performance of density functional theory (DFT) using five different exchange-correlation functionals with four coupled cluster theory based wave function methods in the calculation of geometrical derivatives of the polarizability tensor of methane. The polarizability gradient...

Fast Algorithms for Earth Mover Distance Based on Optimal Transport and L1 Regularization II

Science.gov (United States)

2016-09-01

gradient ascent in the dual variable Φ and a gradient descent in the primal variable m. In our updates for (6), we use simple exact formulae. Since the...0. References [1] Luigi Ambrosio, Nicola Gigli, and Giuseppe Savaré. Gradient flows: in metric spaces and in the space of probability measures...continuity and summability of transport densities: simpler proofs and new estimates. Calculus of Variations and Partial Differential Equations, 36 (3

Nonlinear concentration gradients regulated by the width of channels for observation of half maximal inhibitory concentration (IC50) of transporter proteins.

Science.gov (United States)

Abe, Yuta; Kamiya, Koki; Osaki, Toshihisa; Sasaki, Hirotaka; Kawano, Ryuji; Miki, Norihisa; Takeuchi, Shoji

2015-08-21

This paper describes a simple microfluidic device that can generate nonlinear concentration gradients. We changed the "width" of channels that can drastically shorten the total microfluidic channel length and simplify the microfluidic network design rather than the "length" of channels. The logarithmic concentration gradients generated by the device were in good agreement with those obtained by simulation. Using this device, we evaluated a probable IC50 value of the ABC transporter proteins by the competitive transport assays at five different logarithmic concentrations. This probable IC50 value was in good agreement with an IC50 value (0.92 μM) obtained at the diluted concentrations of seven points.

Transport maps and dimension reduction for Bayesian computation

KAUST Repository

Marzouk, Youssef

2015-01-01

We introduce a new framework for efficient sampling from complex probability distributions, using a combination of optimal transport maps and the Metropolis-Hastings rule. The core idea is to use continuous transportation to transform typical Metropolis proposal mechanisms (e.g., random walks, Langevin methods) into non-Gaussian proposal distributions that can more effectively explore the target density. Our approach adaptively constructs a lower triangular transport map—an approximation of the Knothe-Rosenblatt rearrangement—using information from previous MCMC states, via the solution of an optimization problem. This optimization problem is convex regardless of the form of the target distribution. It is solved efficiently using a Newton method that requires no gradient information from the target probability distribution; the target distribution is instead represented via samples. Sequential updates enable efficient and parallelizable adaptation of the map even for large numbers of samples. We show that this approach uses inexact or truncated maps to produce an adaptive MCMC algorithm that is ergodic for the exact target distribution. Numerical demonstrations on a range of parameter inference problems show order-of-magnitude speedups over standard MCMC techniques, measured by the number of effectively independent samples produced per target density evaluation and per unit of wallclock time. We will also discuss adaptive methods for the construction of transport maps in high dimensions, where use of a non-adapted basis (e.g., a total order polynomial expansion) can become computationally prohibitive. If only samples of the target distribution, rather than density evaluations, are available, then we can construct high-dimensional transformations by composing sparsely parameterized transport maps with rotations of the parameter space. If evaluations of the target density and its gradients are available, then one can exploit the structure of the variational

Transport maps and dimension reduction for Bayesian computation

KAUST Repository

Marzouk, Youssef

2015-01-07

We introduce a new framework for efficient sampling from complex probability distributions, using a combination of optimal transport maps and the Metropolis-Hastings rule. The core idea is to use continuous transportation to transform typical Metropolis proposal mechanisms (e.g., random walks, Langevin methods) into non-Gaussian proposal distributions that can more effectively explore the target density. Our approach adaptively constructs a lower triangular transport map—an approximation of the Knothe-Rosenblatt rearrangement—using information from previous MCMC states, via the solution of an optimization problem. This optimization problem is convex regardless of the form of the target distribution. It is solved efficiently using a Newton method that requires no gradient information from the target probability distribution; the target distribution is instead represented via samples. Sequential updates enable efficient and parallelizable adaptation of the map even for large numbers of samples. We show that this approach uses inexact or truncated maps to produce an adaptive MCMC algorithm that is ergodic for the exact target distribution. Numerical demonstrations on a range of parameter inference problems show order-of-magnitude speedups over standard MCMC techniques, measured by the number of effectively independent samples produced per target density evaluation and per unit of wallclock time. We will also discuss adaptive methods for the construction of transport maps in high dimensions, where use of a non-adapted basis (e.g., a total order polynomial expansion) can become computationally prohibitive. If only samples of the target distribution, rather than density evaluations, are available, then we can construct high-dimensional transformations by composing sparsely parameterized transport maps with rotations of the parameter space. If evaluations of the target density and its gradients are available, then one can exploit the structure of the variational

Fault-Related Controls on Upward Hydrothermal Flow: An Integrated Geological Study of the Têt Fault System, Eastern Pyrénées (France

Directory of Open Access Journals (Sweden)

Audrey Taillefer

2017-01-01

Full Text Available The way faults control upward fluid flow in nonmagmatic hydrothermal systems in extensional context is still unclear. In the Eastern Pyrénées, an alignment of twenty-nine hot springs (29°C to 73°C, along the normal Têt fault, offers the opportunity to study this process. Using an integrated multiscale geological approach including mapping, remote sensing, and macro- and microscopic analyses of fault zones, we show that emergence is always located in crystalline rocks at gneiss-metasediments contacts, mostly in the Têt fault footwall. The hot springs distribution is related to high topographic reliefs, which are associated with fault throw and segmentation. In more detail, emergence localizes either (1 in brittle fault damage zones at the intersection between the Têt fault and subsidiary faults or (2 in ductile faults where dissolution cavities are observed along foliations, allowing juxtaposition of metasediments. Using these observations and 2D simple numerical simulation, we propose a hydrogeological model of upward hydrothermal flow. Meteoric fluids, infiltrated at high elevation in the fault footwall relief, get warmer at depth because of the geothermal gradient. Topography-related hydraulic gradient and buoyancy forces cause hot fluid rise along permeability anisotropies associated with lithological juxtapositions, fracture, and fault zone compositions.

Density limit and cross-field edge transport scaling in Alcator C-Mod

International Nuclear Information System (INIS)

LaBombard, B.; Greenwald, M.; Hughes, J.W.; Lipschultz, B.; Mossessian, D.; Terry, J.L.; Boivin, R.L.; Carreras, B.A.; Pitcher, C.S.; Zweben, S.J.

2003-01-01

Recent experiments in Alcator C-Mod have uncovered a direct link between the character and scaling of cross-field particle transport in the edge plasma and the density limit, n G . As n-bar e /n G is increased from low values to values approaching ∼1, an ordered progression in the cross-field edge transport physics occurs: first benign cross-field heat convection, then cross-field heat convection impacting the scrape-off layer (SOL) power loss channels and reducing the separatrix electron temperature, and finally 'bursty' transport (normally associated with the far SOL) invading into closed flux surface regions and carrying a convective power loss that impacts the power balance of the discharge. These observations suggest that SOL transport and its scaling with plasma conditions plays a key role in setting the empirically observed density limit scaling law. (author)

Numerical Studies of Electron Acceleration Behind Self-Modulating Proton Beam in Plasma with a Density Gradient

CERN Document Server

Petrenko, A.; Sosedkin, A.

2016-01-01

Presently available high-energy proton beams in circular accelerators carry enough momentum to accelerate high-intensity electron and positron beams to the TeV energy scale over several hundred meters of the plasma with a density of about 1e15 1/cm^3. However, the plasma wavelength at this density is 100-1000 times shorter than the typical longitudinal size of the high-energy proton beam. Therefore the self-modulation instability (SMI) of a long (~10 cm) proton beam in the plasma should be used to create the train of micro-bunches which would then drive the plasma wake resonantly. Changing the plasma density profile offers a simple way to control the development of the SMI and the acceleration of particles during this process. We present simulations of the possible use of a plasma density gradient as a way to control the acceleration of the electron beam during the development of the SMI of a 400 GeV proton beam in a 10 m long plasma. This work is done in the context of the AWAKE project --- the proof-of-prin...

Transport of jundiá Rhamdia quelen juveniles at different loading densities: water quality and blood parameters

Directory of Open Access Journals (Sweden)

Paulo César Falanghe Carneiro

Full Text Available Fish transportation is a common practice on fish farms and is considered to be a stressor that could negatively affect fish health. The objective of this study was to evaluate several physiological responses of stress in jundiá caused by transport at different loading densities. Jundiá juveniles were placed in plastic bags on a mechanical transport simulator for four hours at four different loading densities (75, 150, 250 and 350 g L-1 and then transferred to sixteen 80-L plastic boxes for 96 hours after transport. Water samples were collected before and after transport to measure dissolved oxygen, temperature, pH and ammonia levels. Blood samples were taken at departure and arrival, as well as at 24 and 96 hours after transport to monitor cortisol, glucose, ammonia, chloride and hematocrit levels. Water ammonia levels were found to increase gradually as loading densities increased. Plasma ammonia was higher after transport in fish from all treatments. Compared to initial values, substantial increases in plasma cortisol and ammonia levels were detected mainly in those fish submitted to the highest loading density. Blood glucose appeared to be positively influenced by the increase of transport densities. No statistical differences were observed in any of the other blood parameters. The costs in fish culture, as in other animal production systems, must be minimized and fish producers depend on optimal techniques to ensure better profit. Therefore, based on fish survival and the physiological indicators determined in the present study, especially during recovery, the best density at which to transport jundiá in plastic bags for four hours is about 350 g/L.

Theory of neoclassical resistivity-gradient-driven turbulence

International Nuclear Information System (INIS)

Kwon, O.J.; Diamond, P.H.; Hahm, T.S.

1988-12-01

It is shown that rippling instabilities can tap the density gradient expansion free energy source through the density dependence of the neoclassical resistivity. Linear analyses show that the region where neoclassical rippling modes are significantly excited extends from the edge of the plasma to the region where ν/sub *e/ ≤ 1. Since these modes are non-dispersive, diamagnetic effects are negligible in comparison to the nonlinear decorrelation rate at saturation. Thus, the relevant regime is the 'strong turbulence' regime. The turbulent radial diffusivities of the temperature and the density are obtained as eigenvalues of the renormalized eigenmode equations at steady state. The density gradient acts to enhance the level of turbulence, compared to that driven by the temperature gradient alone. The saturated turbulent state is characterized by: current decoupling, the breakdown of Boltzmann relation, a radial mode scale of density fluctuations exceeding that of temperature fluctuations, implying that density diffusivity exceeds temperature diffusivity, and that density fluctuation levels exceed temperature fluctuation levels. Magnetic fluctuation levels are negligible. 29 refs., 1 fig

Stochastic transport models for mixing in variable-density turbulence

Science.gov (United States)

Bakosi, J.; Ristorcelli, J. R.

2011-11-01

In variable-density (VD) turbulent mixing, where very-different- density materials coexist, the density fluctuations can be an order of magnitude larger than their mean. Density fluctuations are non-negligible in the inertia terms of the Navier-Stokes equation which has both quadratic and cubic nonlinearities. Very different mixing rates of different materials give rise to large differential accelerations and some fundamentally new physics that is not seen in constant-density turbulence. In VD flows material mixing is active in a sense far stronger than that applied in the Boussinesq approximation of buoyantly-driven flows: the mass fraction fluctuations are coupled to each other and to the fluid momentum. Statistical modeling of VD mixing requires accounting for basic constraints that are not important in the small-density-fluctuation passive-scalar-mixing approximation: the unit-sum of mass fractions, bounded sample space, and the highly skewed nature of the probability densities become essential. We derive a transport equation for the joint probability of mass fractions, equivalent to a system of stochastic differential equations, that is consistent with VD mixing in multi-component turbulence and consistently reduces to passive scalar mixing in constant-density flows.

Droplet and bubble nucleation modeled by density gradient theory – cubic equation of state versus saft model

Directory of Open Access Journals (Sweden)

Hrubý Jan

2012-04-01

Full Text Available The study presents some preliminary results of the density gradient theory (GT combined with two different equations of state (EoS: the classical cubic equation by van der Waals and a recent approach based on the statistical associating fluid theory (SAFT, namely its perturbed-chain (PC modification. The results showed that the cubic EoS predicted for a given surface tension the density profile with a noticeable defect. Bulk densities predicted by the cubic EoS differed as much as by 100 % from the reference data. On the other hand, the PC-SAFT EoS provided accurate results for density profile and both bulk densities in the large range of temperatures. It has been shown that PC-SAFT is a promising tool for accurate modeling of nucleation using the GT. Besides the basic case of a planar phase interface, the spherical interface was analyzed to model a critical cluster occurring either for nucleation of droplets (condensation or bubbles (boiling, cavitation. However, the general solution for the spherical interface will require some more attention due to its numerical difficulty.

Gibbs Free-Energy Gradient along the Path of Glucose Transport through Human Glucose Transporter 3.

Science.gov (United States)

Liang, Huiyun; Bourdon, Allen K; Chen, Liao Y; Phelix, Clyde F; Perry, George

2018-06-11

Fourteen glucose transporters (GLUTs) play essential roles in human physiology by facilitating glucose diffusion across the cell membrane. Due to its central role in the energy metabolism of the central nervous system, GLUT3 has been thoroughly investigated. However, the Gibbs free-energy gradient (what drives the facilitated diffusion of glucose) has not been mapped out along the transport path. Some fundamental questions remain. Here we present a molecular dynamics study of GLUT3 embedded in a lipid bilayer to quantify the free-energy profile along the entire transport path of attracting a β-d-glucose from the interstitium to the inside of GLUT3 and, from there, releasing it to the cytoplasm by Arrhenius thermal activation. From the free-energy profile, we elucidate the unique Michaelis-Menten characteristics of GLUT3, low K M and high V MAX , specifically suitable for neurons' high and constant demand of energy from their low-glucose environments. We compute GLUT3's binding free energy for β-d-glucose to be -4.6 kcal/mol in agreement with the experimental value of -4.4 kcal/mol ( K M = 1.4 mM). We also compute the hydration energy of β-d-glucose, -18.0 kcal/mol vs the experimental data, -17.8 kcal/mol. In this, we establish a dynamics-based connection from GLUT3's crystal structure to its cellular thermodynamics with quantitative accuracy. We predict equal Arrhenius barriers for glucose uptake and efflux through GLUT3 to be tested in future experiments.

A semi-analytical study on the residual transport of salinity and sediment trapping in well-mixed estuaries

NARCIS (Netherlands)

Wei, X.; Kumar, M.; Schuttelaars, H.M.

2016-01-01

Along-channel and cross-channel sediment transport in tidal estuaries is usually driven by tides, density gradients, Coriolis’s force, wind stress, channel curvature and bathymetric variations. Since the water motion is influenced by density-induced gravitational circulation which in turn affects

Controlling DIII-D QH-Mode Particle and Electron Thermal Transport with ECH

Science.gov (United States)

Ernst, D. R.; Burrell, K. H.; Rhodes, T. L.; Guttenfelder, W.; McKee, G. R.; Grierson, B. A.; Holland, C.; Dimits, A.; Petty, C. C.; Schmitz, L.; Wang, G.; Zeng, L.; Doyle, E. J.; Austin, M. E.

2014-10-01

Quiescent H-mode core particle transport and density peaking are locally controlled by modulated electron cyclotron heating (ECH) at ρ ~ 0 . 2 . Gyrokinetic simulations show density gradient driven trapped electron modes (TEMs) are only unstable in the inner core, where the density profile flattens in response to ECH. Thus α-heating could reduce density peaking, providing burn control. Density fluctuations from Doppler backscattering intensify at TEM wavenumbers kθρs ~ 0 . 8 during ECH, while new quasi-coherent modes are observed with adjacent toroidal mode numbers consistent with TEMs. Separately, ECH at two-deposition locations (r / a ~ ρ = 0 . 5 & 0.7) varied the electron temperature gradient. A jump in ``heat pulse'' diffusivity during the scan indicates a critical gradient was crossed. Work supported by the US DOE under DE-FC02-08ER54966, DE-FC02-04ER54698, DE-FG02-08ER54984, DE-AC02-09CH11466, DE-FG02-89ER53296, DE-FC02-11ER55104, DE-AC52-07NA27344 & DE-FG03-97ER54415.

Internal transport barrier in tokamak and helical plasmas

Science.gov (United States)

Ida, K.; Fujita, T.

2018-03-01

The differences and similarities between the internal transport barriers (ITBs) of tokamak and helical plasmas are reviewed. By comparing the characteristics of the ITBs in tokamak and helical plasmas, the mechanisms of the physics for the formation and dynamics of the ITB are clarified. The ITB is defined as the appearance of discontinuity of temperature, flow velocity, or density gradient in the radius. From the radial profiles of temperature, flow velocity, and density the ITB is characterized by the three parameters of normalized temperature gradient, R/{L}T, the location, {ρ }{ITB}, and the width, W/a, and can be expressed by ‘weak’ ITB (small R/{L}T) or ‘strong’ (large R/{L}T), ‘small’ ITB (small {ρ }{ITB}) or ‘large’ ITB (large {ρ }{ITB}), and ‘narrow’ (small W/a) or ‘wide’ (large W/a). Three key physics elements for the ITB formation, radial electric field shear, magnetic shear, and rational surface (and/or magnetic island) are described. The characteristics of electron and ion heat transport and electron and impurity transport are reviewed. There are significant differences in ion heat transport and electron heat transport. The dynamics of ITB formation and termination is also discussed. The emergence of the location of the ITB is sometimes far inside the ITB foot in the steady-state phase and the ITB region shows radial propagation during the formation of the ITB. The non-diffusive terms in momentum transport and impurity transport become more dominant in the plasma with the ITB. The reversal of the sign of non-diffusive terms in momentum transport and impurity transport associated with the formation of the ITB reported in helical plasma is described. Non-local transport plays an important role in determining the radial profile of temperature and density. The spontaneous change in temperature curvature (second radial derivative of temperature) in the ITB region is described. In addition, the key parameters of the control of the

Bubble Clouds and their Transport within the Surf Zone as Measured with a Distributed Array of Upward-Looking Sonars

National Research Council Canada - National Science Library

Dahl, Peter

2000-01-01

... in the surf zone and the effects of these bubbles on acoustic propagation. This paper discusses data gathered by the Applied Physics Laboratory, University of Washington, using a set of four upward-looking sonars (frequency 240 kHz...

Benchmarking variable-density flow in saturated and unsaturated porous media

Science.gov (United States)

Guevara Morel, Carlos Roberto; Cremer, Clemens; Graf, Thomas

2015-04-01

In natural environments, fluid density and viscosity can be affected by spatial and temporal variations of solute concentration and/or temperature. These variations can occur, for example, due to salt water intrusion in coastal aquifers, leachate infiltration from waste disposal sites and upconing of saline water from deep aquifers. As a consequence, potentially unstable situations may exist in which a dense fluid overlies a less dense fluid. This situation can produce instabilities that manifest as dense plume fingers that move vertically downwards counterbalanced by vertical upwards flow of the less dense fluid. Resulting free convection increases solute transport rates over large distances and times relative to constant-density flow. Therefore, the understanding of free convection is relevant for the protection of freshwater aquifer systems. The results from a laboratory experiment of saturated and unsaturated variable-density flow and solute transport (Simmons et al., Transp. Porous Medium, 2002) are used as the physical basis to define a mathematical benchmark. The HydroGeoSphere code coupled with PEST are used to estimate the optimal parameter set capable of reproducing the physical model. A grid convergency analysis (in space and time) is also undertaken in order to obtain the adequate spatial and temporal discretizations. The new mathematical benchmark is useful for model comparison and testing of variable-density variably saturated flow in porous media.

Physics of transport in Tokamaks

International Nuclear Information System (INIS)

Garbet, X.; Asp, E.; Bourdelle, C.; Hoang, T.; Imbeaux, F.; Joffrin, E.; Litaudon, X.; Angioni, C.; Manini, A.; Peeter, A.; Ryter, F.; Baranov, Y.; Cordey, G.; McDonald, D.C.; Parail, V.; Valovic, M.; Thyagaraja, A.; Voitsekhovitch, I.; Budny, R.; Kirneva, N.; Hogeweij, D.; Nordman, H.; Weilland, J.; Tala, T.; Weisen, H.; Zabolotsky, A.

2004-01-01

This paper is an overview of recent results related to turbulent particle and heat transport, and triggering of Internal Transport Barriers. Particle transport is characterised by a pinch velocity that is found to be larger than the value predicted by theory of collisional transport (Ware pinch) in L-mode plasmas. Also it increases with magnetic shear. In H-mode, density peaking decreases with collisionality. Pinch velocity reaches the Ware value for large collision frequencies. Heat transport has made progress along two directions: dimensionless scaling laws and analysis of modulation experiments. Dimensionless scaling law of thermal confinement agrees with the prediction for electrostatic turbulence. Dependence with collisionality remains to be understood. Heat modulation experiments have been investigated in several devices using a critical gradient model, micro-stability analysis and predictive modelling. Thresholds and stiffness are correctly reproduced by stability analysis and modelling with Weiland model. Analysis with a critical gradient model leads to a large variability of stiffness. Finally the question of triggering Internal Transport Barriers has been addressed by analysing electron transport barriers. It is confirmed that negative magnetic shear combined with Shafranov shift is a robust stabilizing mechanism. However, some well established features of internal barriers are hardly explained by theory, in particular the role of low order rational values of the minimum safety factor, and the existence of multiple barriers. (authors)

Estimates of potential radionuclide migration at the Bullion site

International Nuclear Information System (INIS)

Brikowski, T.H.

1992-04-01

The Bullion site in Area 20 of the Nevada Test Site has been selected for an intensive study of the hydrologic consequences of underground testing, including subsequent radionuclide migration. The bulk of the chimney and cavity lie in zeolitized tuffs of low hydraulic conductivity, while the base of the cavity may extend downward into more conductive rhyolite flows. A mathematical analog to the Bullion setting is used here to estimate expected radionuclide migration rates and concentrations. Because of a lack of hydrologic data at the site, two contrasting scenarios are considered. The first is downward-transport, in which downward hydraulic gradients flush chimney contents into the conductive underlying units, enhancing migration. The other is upward-transport, in which upward gradients tend to drive chimney contents into the low-conductivity zeolitized tuffs, discouraging migration. In the downward-transport scenario, radionuclide travel times and concentrations are predicted to be similar to those encountered at Cheshire, requiring approximately 10 years to reach a proposed well 300 m downgradient. The upward transport scenario yields predicted travel times on the order of 2,000 years to the downgradient well. The most likely scenario is a combination of these results, with vertical movement playing a limited role. Radionuclides injected directly into the rhyolites should migrate laterally very quickly, with travel times as in the downward-transport scenario. Those in the zeolitized tuff-walled portion of the chimney should migrate extremely slowly, as in the upward-transport scenario

Comparative validation using quantitative real-time PCR (qPCR and conventional PCR of bovine semen centrifuged in continuous density gradient

Directory of Open Access Journals (Sweden)

M.V. Resende

2011-06-01

Full Text Available The objective of the present study was to determine the sperm enrichment with X-bearing spermatozoa, after one centrifugation in a Percoll or OptiPrep continuous density gradient, using quantitative real-time polymerase chain reaction (qPCR of sperm DNA and resultant in vitro-produced bovine embryos by PCR. Frozen/thawed sperm was layered on density gradients and the tubes were centrifuged. Supernatants were gently aspirated and the sperm recovered from the bottom of the tubes. Cleavage and blastocyst rates were determined through in vitro production of embryos and PCR was performed to identify the embryos' genetic sex. A difference in blastocyst rate was found in the Percoll treatment compared to OptiPrep (P<0.05. The percentage of female embryos in the Percoll and OptiPrep groups was 62.0% and 47.1%, respectively. These results were confirmed by qPCR of spermatozoa DNA and underestimation was seen only in the Percoll group. It was possible to sexing sperm using simple approach.

Autoradiography and density gradient separation of technetium-99m-Exametazime (HMPAO) labelled leucocytes reveals selectivity for eosinophils

Energy Technology Data Exchange (ETDEWEB)

Puncher, M.R.B. [Biological Lab., Univ. of Kent, Canterbury (United Kingdom); Blower, P.J. [Nuclear Medicine Dept., Kent and Canterbury Hospital (United Kingdom)

1994-11-01

Technetium-99m-Exametazime (HMPAO) is widely used for radiolabelling leucocytes for localization of infection. The subcellular distribution of radionuclide in the labelled cells and the distribution of radioactivity among the leucocyte population are incompletely understood. Frozen section autoradiography was used to determine quantitatively the distribution of {sup 99m}Tc in leucocytes labelled with {sup 99m}Tc-Exametazime. Sections of rapidly frozen suspensions of labelled leucocytes in plasma were autoradiographed on Ilford K2 emulsion and stained with haematoxylin and eosin. Neutrophils, eosinophils and mononuclear cells were separated by Percoll density gradient centrifugation. Cell nuclei were isolated by a rapid cell-breakage and fractionation method. In a typical experiment mean grain densities [grains/100 {mu}m{sup 2} (ESD)] over cells were: eosinophils 31.2 (18.4), neutrophils 3.5 (3.5), mononuclear cells 4.2 (5.1). Mean grain numbers per cell (ESD) were: eosinophils 13 (6.8), neutrophils 1.3 (1.3), mononuclear cells 1.1 (1.3). These findings were confirmed by separation of labelled leucocytes on discontinuous density gradients. In four separation experiments, the mean activity-per-cell ratio for eosinophils to neutrophils was 10.1 (4.8):1, and for eosinophils to mononuclear cells, 14.1 (6.7):1. The subcellular distribution of the label was investigated using image analysis of autoradiographs and cell fractionation. This revealed no selectivity for nuclear or extranuclear compartments. It may be concluded that {sup 99m}Tc-Exametazime has strong selectivity for eosinophils over other leucocytes but no selectivity for nuclear/cytoplasmic compartments. (orig.)

Particle transport and fluctuation characteristics around neoclassically optimized configurations in LHD

International Nuclear Information System (INIS)

Tanaka, K.; Michael, C.; Vyacheslavov, L.N.

2008-01-01

Density profiles in LHD were measured and particle transport coefficients were estimated from density modulation experiments in LHD. The data set contains the wide region of discharge condition. The dataset of different magnetic axis, toroidal magnetic field and heating power provided data set of widely scanned neoclassical transport. At minimized neoclassical transport configuration in the dataset (Rax=3.5m, Bt=2.8T) showed peaked density profile. Its peaking factor increased gradually with decrease of collisional frequency. This is a similar result observed in tokamak data base. At other configuration, peaking factor reduced with decrease of collisional frequency. Data set showed that larger contribution of neoclassical transport produced hollowed density profile. Comparison between neoclassical and experimental estimated particle diffusivity showed different minimum condition. This suggests neoclassical optimization is not same as anomalous optimization. Clear difference of spatial profile of turbulence was observed between hollowed and peaked density profiles. Major part of fluctuation existed in the unstable region of linear growth rate of ion temperature gradient mode. (author)

Transport of particles, drops, and small organisms in density stratified fluids

Science.gov (United States)

Ardekani, Arezoo M.; Doostmohammadi, Amin; Desai, Nikhil

2017-10-01

Sedimenting particles and motile organisms are ubiquitously found in oceans and lakes, where density stratification naturally occurs due to temperature or salinity gradients. We explore the effects of stratification on the fundamental hydrodynamics of settling particles, rising drops, and small organisms. The results of our direct numerical simulations of the sedimentation of particles show that the presence of vertical density gradients in the water column can substantially affect the settling dynamics of a particle, interaction between a pair of particles, and settling rates and microstructure of suspension of particles. We show that elongation of particles affects both the settling orientation and the settling rate of particles in stratified fluids, which will have direct consequences on the vertical flux of particulate matter and carbon flux in the ocean. We further demonstrate an unexpected effect of buoyancy, potentially affecting a broad range of processes at pycnoclines in oceans and lakes. In particular, stratification has a major effect on the flow field, energy expenditure, and nutrient uptake of small organisms. In addition, the role of stratification in pattern formation of bioconvection plumes of algal cells and in biogenic mixing is investigated. In particular, the numerical approach allows for considering the effects of background turbulence and hydrodynamic perturbations produced by swimming organisms, shedding light on the contribution of organisms in the mixing process in aqueous environments.

Utility Assessment of Specificity in Upward Feedback Instruments for Leadership Development

National Research Council Canada - National Science Library

Wardak, Theresa

2003-01-01

...) and the other is the recently developed, non-proprietary Upward Feedback Instrument (2002). The Upward Feedback Instrument was designed to measure leadership behaviors at a more specific level...

Impurity transport in internal transport barrier discharges on JET

International Nuclear Information System (INIS)

Dux, R.

2002-01-01

In JET plasmas with internal transport barrier (ITB) the behaviour of metallic and low-Z impurities (C, Ne) was investigated. In ITB discharges with reversed shear, the metallic impurities accumulate in cases with too strong peaking of the density profile, while the concentration of low-Z elements C and Ne is only mildly peaked. The accumulation might be so strong, that the central radiation approximately equals the central heating power followed by a radiative collapse of the transport barrier. The radial location with strong impurity gradients (convective barrier) was identified to be situated inside (not at!) the heat flux barrier. Calculations of neo-classical transport were performed for these discharges, including impurity-impurity collisions. It was found, that the observed Z-dependence of the impurity peaking and the location of the impurity 'barrier' can be explained with neo-classical transport. ITB discharges with monotonic shear show less inward convection and seem to be advantageous with respect to plasma purity. (author)

Transport analysis of high radiation and high density plasmas in the ASDEX Upgrade tokamak

Directory of Open Access Journals (Sweden)

Casali L.

2014-01-01

Full Text Available Future fusion reactors, foreseen in the “European road map” such as DEMO, will operate under more demanding conditions compared to present devices. They will require high divertor and core radiation by impurity seeding to reduce heat loads on divertor target plates. In addition, DEMO will have to work at high core densities to reach adequate fusion performance. The performance of fusion reactors depends on three essential parameters: temperature, density and energy confinement time. The latter characterizes the loss rate due to both radiation and transport processes. The DEMO foreseen scenarios described above were not investigated so far, but are now addressed at the ASDEX Upgrade tokamak. In this work we present the transport analysis of such scenarios. Plasma with high radiation by impurity seeding: transport analysis taking into account the radiation distribution shows no change in transport during impurity seeding. The observed confinement improvement is an effect of higher pedestal temperatures which extend to the core via stiffness. A non coronal radiation model was developed and compared to the bolometric measurements in order to provide a reliable radiation profile for transport calculations. High density plasmas with pellets: the analysis of kinetic profiles reveals a transient phase at the start of the pellet fuelling due to a slower density build up compared to the temperature decrease. The low particle diffusion can explain the confinement behaviour.

Wetting of flat gradient surfaces.

Science.gov (United States)

Bormashenko, Edward

2018-04-01

Gradient, chemically modified, flat surfaces enable directed transport of droplets. Calculation of apparent contact angles inherent for gradient surfaces is challenging even for atomically flat ones. Wetting of gradient, flat solid surfaces is treated within the variational approach, under which the contact line is free to move along the substrate. Transversality conditions of the variational problem give rise to the generalized Young equation valid for gradient solid surfaces. The apparent (equilibrium) contact angle of a droplet, placed on a gradient surface depends on the radius of the contact line and the values of derivatives of interfacial tensions. The linear approximation of the problem is considered. It is demonstrated that the contact angle hysteresis is inevitable on gradient surfaces. Electrowetting of gradient surfaces is discussed. Copyright © 2018 Elsevier Inc. All rights reserved.

Study of Streamers in Gradient Density Air: Table Top Modeling of Red Sprites

Science.gov (United States)

Opaits, D. F.; Shneider, M. N.; Howard, P. J.; Miles, R. B.; Milikh, G. M.

2009-12-01

Sprites and blue jets develop in the upper atmosphere where ambient density changes drastically over their lengths. Theoretical analysis of Red Sprites [1] and Blue Jets [2,3] are based on the streamer tip parameters’ functional dependence on a local gas density N(h). At the moment there is a lack of experimental data for streamer propagation in a non-uniform ambient gas density. Small scale experiments in controllable conditions are important for validation of analytical models as well as numerical simulations, which can be used for the investigation of real scale plasma phenomena that develop above thunderclouds. Controllable, non-uniform gas density can be achieved in laboratory conditions in super sonic nozzles, fast centrifuges or gas filled tubes with a non-uniform temperature distribution along the axis. The latter approach was used in the present work. A quartz tube, approximately one foot in length, was filled with air at different pressures. A density gradient was created by heating up the top of the tube while keeping the bottom at room temperature. The discharge was initiated by applying a high voltage pulse to a pin electrode at the top of the tube while a flat electrode was grounded at the bottom. Similar to Red Sprites, the streamer propagates downwards into a region of higher density and stops before reaching the lower electrode while the top electrode remains under high potential. This work will present results of streamer propagation at different pressures and voltages. Measurements of current-voltage characteristics as well as integral images will be presented. 1. Y. P.Raizer, G. M. Milikh, M. N. Shneider, and S. V. Novakovski (1998), J. Phys. D: Appl. Phys. 31, 3255-3264. 2. Y. P.Raizer, G. M. Milikh, and M. N. Shneider (2006), Geophys. Res. Lett., 33, L23801 3. Y .P.Raizer, G. M. Milikh, and M. N. Shneider (2007), J. Atmos. & Solat-Terr. Phys, 69, 925-938

34 CFR 645.1 - What is the Upward Bound Program?

Science.gov (United States)

2010-07-01

... participants the skills and motivation necessary to complete a program of secondary education and to enter and... the following three types of projects: (1) Regular Upward Bound projects. (2) Upward Bound Math and... Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY...

Interactions between Radial Electric Field, Transport and Structure in Helical Plasmas

International Nuclear Information System (INIS)

Ida, Katsumi and others

2006-01-01

Control of the radial electric field is considered to be important in helical plasmas, because the radial electric field and its shear are expected to reduce neoclassical and anomalous transport, respectively. Particle and heat transport, that determines the radial structure of density and electron profiles, sensitive to the structure of radial electric field. On the other hand, the radial electric field itself is determined by the plasma parameters. In general, the sign of the radial electric field is determined by the plasma collisionality, while the magnitude of the radial electric field is determined by the temperature and/or density gradients. Therefore the structure of radial electric field and temperature and density are strongly coupled through the particle and heat transport and formation mechanism of radial electric field. Interactions between radial electric field, transport and structure in helical plasmas is discussed based on the experiments on Large Helical Device

Momentum transport in gyrokinetic turbulence

Energy Technology Data Exchange (ETDEWEB)

Buchholz, Rico

2016-07-01

In this thesis, the gyrokinetic-Vlasov code GKW is used to study turbulent transport, with a focus on radial transport of toroidal momentum. To support the studies on turbulent transport an eigenvalue solver has been implemented into GKW. This allows to find, not only the most unstable mode, but also subdominant modes. Furthermore it is possible to follow the modes in parameter scans. Furthermore, two fundamental mechanisms that can generate an intrinsic rotation have been investigated: profile shearing and the velocity nonlinearity. The study of toroidal momentum transport in a tokamak due to profile shearing reveals that the momentum flux can not be accurately described by the gradient in the turbulent intensity. Consequently, a description using the profile variation is used. A linear model has been developed that is able to reproduce the variations in the momentum flux as the profiles of density and temperature vary, reasonably well. It uses, not only the gradient length of density and temperature profile, but also their derivative, i.e. the second derivative of the logarithm of the temperature and the density profile. It is shown that both first as well as second derivatives contribute to the generation of a momentum flux. A difference between the linear and nonlinear simulations has been found with respect to the behaviour of the momentum flux. In linear simulations the momentum flux is independent of the normalized Larmor radius ρ{sub *}, whereas it is linear in ρ{sub *} for nonlinear simulations, provided ρ{sub *} is small enough (≤4.10{sup -3}). Nonlinear simulations reveal that the profile shearing can generate an intrinsic rotation comparable to that of current experiments. Under reactor conditions, however, the intrinsic rotation from the profile shearing is expected to be small due to the small normalized Larmor radius ρ{sub *}

Two upward lightning at the Eagle Nest tower

OpenAIRE

Montañá Puig, Juan; Van der Velde, Oscar Arnoud; Romero Durán, David; March Nomen, Víctor; Solà de Las Fuentes, Gloria; Pineda Ruegg, Nicolau; Soula, Serge; Hermoso Alameda, Blas

2012-01-01

A new instrument composed by a high speed camera, two high energy detectors, a E-field antenna and a VHF antenna were installed at the Eagle Nest tower (northeast of Spain) during summer 2011. With this equipment several lightning flashes to the tower and its vicinity have been observed. This paper presents two examples: the first was an upward negative leader triggered by a close c1oud-to-ground flash and the second was an upward negative flash not associated with previous lightning activity...

Simulation of upward flux from shallow water-table using UPFLOW model

Directory of Open Access Journals (Sweden)

M. H. Ali

2013-11-01

Full Text Available The upward movement of water by capillary rise from shallow water-table to the root zone is an important incoming flux. For determining exact amount of irrigation requirement, estimation of capillary flux or upward flux is essential. Simulation model can provide a reliable estimate of upward flux under variable soil and climatic conditions. In this study, the performance of model UPFLOW to estimate upward flux was evaluated. Evaluation of model performance was performed with both graphical display and statistical criteria. In distribution of simulated capillary rise values against observed field data, maximum data points lie around the 1:1 line, which means that the model output is reliable and reasonable. The coefficient of determination between observed and simulated values was 0.806 (r = 0.93, which indicates a good inter-relation between observed and simulated values. The relative error, model efficiency, and index of agreement were found as 27.91%, 85.93% and 0.96, respectively. Considering the graphical display of observed and simulated upward flux and statistical indicators, it can be concluded that the overall performance of the UPFLOW model in simulating actual upward flux from a crop field under variable water-table condition is satisfactory. Thus, the model can be used to estimate capillary rise from shallow water-table for proper estimation of irrigation requirement, which would save valuable water from over-irrigation.

Activation of lysosomal P2X4 by ATP transported into lysosomes via VNUT/SLC17A9 using V‐ATPase generated voltage gradient as the driving force

Science.gov (United States)

Zhong, Xi Zoë; Cao, Qi; Sun, Xue

2016-01-01

Key points SLC17A9 proteins function as a lysosomal ATP transporter responsible for lysosomal ATP accumulation.P2X4 receptors act as lysosomal ion channels activated by luminal ATP.SLC17A9‐mediated ATP transport across the lysosomal membrane is suppressed by Bafilomycin A1, the V‐ATPase inhibitor.SLC17A9 mainly uses voltage gradient but not pH gradient generated by the V‐ATPase as the driving force to transport ATP into the lysosome to activate P2X4. Abstract The lysosome contains abundant ATP which plays important roles in lysosome functions and in cell signalling. Recently, solute carrier family 17 member 9 (SLC17A9, also known as VNUT for vesicular nucleotide transporter) proteins were suggested to function as a lysosomal ATP transporter responsible for lysosomal ATP accumulation, and P2X4 receptors were suggested to be lysosomal ion channels that are activated by luminal ATP. However, the molecular mechanism of SLC17A9 transporting ATP and the regulatory mechanism of lysosomal P2X4 are largely unknown. In this study, we report that SLC17A9‐mediated ATP transport across lysosomal membranes is suppressed by Bafilomycin A1, the V‐ATPase inhibitor. By measuring P2X4 activity, which is indicative of ATP transport across lysosomal membranes, we further demonstrated that SLC17A9 mainly uses voltage gradient but not pH gradient as the driving force to transport ATP into lysosomes. This study provides a molecular mechanism for lysosomal ATP transport mediated by SLC17A9. It also suggests a regulatory mechanism of lysosomal P2X4 by SLC17A9. PMID:27477609

Edge and internal transport barrier formations in CHS

International Nuclear Information System (INIS)

Okamura, S.; Minami, T.; Akiyama, T.; Fujisawa, A.; Ida, K.; Iguchi, H.; Isobe, M.; Nagaoka, K.; Nakamura, K.; Nishimura, S.; Matsuoka, K.; Matsushita, H.; Nakano, H.; Nishiura, M.; Ohshima, S.; Shimizu, A.; Suzuki, C.; Takahashi, C.; Toi, K.; Yoshimura, Y.; Yoshinuma, M.; Oishi, T.; Kado, S.

2005-01-01

Edge transport barrier (ETB) formation was observed in CHS. Sharp decrease of Hα emission indicates the quick transition of edge particle transport. Increase of the density gradient at the edge was measured by various profile diagnostics and the improvement of the global energy confinement was confirmed based on the stellarator confinement scaling. The heating power threshold exists. The transition and back transition is controlled by the heating power. The local density measurement by the beam emission spectroscopy shows intermittent burst of the low frequency fluctuations during the ETB formation phase. The ETB formation together with the electron temperature increase (electron ITB) in the core region were observed for the NBI discharges without ECH. (author)

The pressure gradient in the human respiratory tract

Directory of Open Access Journals (Sweden)

Chovancová Michaela

2014-03-01

Full Text Available Respiratory airways cause resistance to air flow during inhalation and exhalation. The pressure gradient is necessary to transport the air from the mount (or nose to pulmonary alveoli. The knowledge of pressure gradient (i.e. respiratory airways resistance is also needed to solve the question of aerosol deposition in the human respiratory tract. The obtained data will be used as boundary conditions for CFD simulations of aerosol transport. Understanding of aerosol transport in the human lungs can help us to determine the health hazard of harmful particles. On the other hand it can be used to set the conditions for transport of medication to the desirable place. This article deals with the description of the mathematical equations defining the pressure gradient and resistance in the bronchial three and describes the geometry used in the calculation.

A substrate independent approach for generation of surface gradients

Energy Technology Data Exchange (ETDEWEB)

Goreham, Renee V. [Mawson Institute, University of South Australia, Mawson Lakes 5095 (Australia); Mierczynska, Agnieszka; Pierce, Madelene [Ian Wark Research Institute, University of South Australia, Mawson Lakes 5095 (Australia); Short, Robert D.; Taheri, Shima; Bachhuka, Akash; Cavallaro, Alex; Smith, Louise E. [Mawson Institute, University of South Australia, Mawson Lakes 5095 (Australia); Vasilev, Krasimir, E-mail: krasimir.vasilev@unisa.edu.au [Mawson Institute, University of South Australia, Mawson Lakes 5095 (Australia)

2013-01-01

Recently, surface gradients have attracted significant interest for various research and technological applications. In this paper, we report a facile and versatile method for generating surface gradients of immobilized nanoparticles, nanotopography and ligands that is independent from the substrate material. The method consists of first depositing a functional polymer layer on a substrate and subsequent time controlled immersion of this functionalized substrate in solution gold nanoparticles (AuNPs), silver nanoparticles (AgNPs) or poly (styrenesulfonate) (PSS). Chemical characterization by X-ray Photoelectron Spectroscopy (XPS) and morphological analysis by Atomic Force Microscopy (AFM) show that the density of nanoparticles and the concentration of PSS across the surface increases in a gradient manner. As expected, time of immersion determines the concentration of surface bound species. We also demonstrate the generation of surface gradients of pure nanotopography. This is achieved by depositing a 5 nm thick plasma polymer layer on top of the number density gradient of nanoparticles to achieve a homogeneous surface chemistry. The surface independent approach for generation of surface gradients presented in this paper may open opportunities for a wider use of surface gradient in research and in various technologies. - Highlights: ► We present a substrate independent approach for generation of surface gradients. ► We demonstrate well-defined density gradients of gold and silver nanoparticles. ► We provide an example of pure surface nanotopography gradients. ► We demonstrate concentration gradients of bound ligands.

A substrate independent approach for generation of surface gradients

International Nuclear Information System (INIS)

Goreham, Renee V.; Mierczynska, Agnieszka; Pierce, Madelene; Short, Robert D.; Taheri, Shima; Bachhuka, Akash; Cavallaro, Alex; Smith, Louise E.; Vasilev, Krasimir

2013-01-01

Recently, surface gradients have attracted significant interest for various research and technological applications. In this paper, we report a facile and versatile method for generating surface gradients of immobilized nanoparticles, nanotopography and ligands that is independent from the substrate material. The method consists of first depositing a functional polymer layer on a substrate and subsequent time controlled immersion of this functionalized substrate in solution gold nanoparticles (AuNPs), silver nanoparticles (AgNPs) or poly (styrenesulfonate) (PSS). Chemical characterization by X-ray Photoelectron Spectroscopy (XPS) and morphological analysis by Atomic Force Microscopy (AFM) show that the density of nanoparticles and the concentration of PSS across the surface increases in a gradient manner. As expected, time of immersion determines the concentration of surface bound species. We also demonstrate the generation of surface gradients of pure nanotopography. This is achieved by depositing a 5 nm thick plasma polymer layer on top of the number density gradient of nanoparticles to achieve a homogeneous surface chemistry. The surface independent approach for generation of surface gradients presented in this paper may open opportunities for a wider use of surface gradient in research and in various technologies. - Highlights: ► We present a substrate independent approach for generation of surface gradients. ► We demonstrate well-defined density gradients of gold and silver nanoparticles. ► We provide an example of pure surface nanotopography gradients. ► We demonstrate concentration gradients of bound ligands

Elevation gradient of successful plant traits for colonizing alpine summits under climate change

International Nuclear Information System (INIS)

Matteodo, Magalì; Wipf, Sonja; Stöckli, Veronika; Rixen, Christian; Vittoz, Pascal

2013-01-01

Upward migration of plant species due to climate change has become evident in several European mountain ranges. It is still, however, unclear whether certain plant traits increase the probability that a species will colonize mountain summits or vanish, and whether these traits differ with elevation. Here, we used data from a repeat survey of the occurrence of plant species on 120 summits, ranging from 2449 to 3418 m asl, in south-eastern Switzerland to identify plant traits that increase the probability of colonization or extinction in the 20th century. Species numbers increased across all plant traits considered. With some traits, however, numbers increased proportionally more. The most successful colonizers seemed to prefer warmer temperatures and well-developed soils. They produced achene fruits and/or seeds with pappus appendages. Conversely, cushion plants and species with capsule fruits were less efficient as colonizers. Observed changes in traits along the elevation gradient mainly corresponded to the natural distribution of traits. Extinctions did not seem to be clearly related to any trait. Our study showed that plant traits varied along both temporal and elevational gradients. While seeds with pappus seemed to be advantageous for colonization, most of the trait changes also mirrored previous gradients of traits along elevation and hence illustrated the general upward migration of plant species. An understanding of the trait characteristics of colonizing species is crucial for predicting future changes in mountain vegetation under climate change. (letter)

Relationship between defect density and charge carrier transport in amorphous and microcrystalline silicon

International Nuclear Information System (INIS)

Astakhov, Oleksandr; Carius, Reinhard; Finger, Friedhelm; Petrusenko, Yuri; Borysenko, Valery; Barankov, Dmytro

2009-01-01

The influence of dangling-bond defects and the position of the Fermi level on the charge carrier transport properties in undoped and phosphorous doped thin-film silicon with structure compositions all the way from highly crystalline to amorphous is investigated. The dangling-bond density is varied reproducibly over several orders of magnitude by electron bombardment and subsequent annealing. The defects are investigated by electron-spin-resonance and photoconductivity spectroscopies. Comparing intrinsic amorphous and microcrystalline silicon, it is found that the relationship between defect density and photoconductivity is different in both undoped materials, while a similar strong influence of the position of the Fermi level on photoconductivity via the charge carrier lifetime is found in the doped materials. The latter allows a quantitative determination of the value of the transport gap energy in microcrystalline silicon. The photoconductivity in intrinsic microcrystalline silicon is, on one hand, considerably less affected by the bombardment but, on the other hand, does not generally recover with annealing of the defects and is independent from the spin density which itself can be annealed back to the as-deposited level. For amorphous silicon and material prepared close to the crystalline growth regime, the results for nonequilibrium transport fit perfectly to a recombination model based on direct capture into neutral dangling bonds over a wide range of defect densities. For the heterogeneous microcrystalline silicon, this model fails completely. The application of photoconductivity spectroscopy in the constant photocurrent mode (CPM) is explored for the entire structure composition range over a wide variation in defect densities. For amorphous silicon previously reported linear correlation between the spin density and the subgap absorption is confirmed for defect densities below 10 18 cm -3 . Beyond this defect level, a sublinear relation is found i.e., not

Parallel transport in ideal magnetohydrodynamics and applications to resistive wall modes

International Nuclear Information System (INIS)

Finn, J.M.; Gerwin, R.A.

1996-01-01

It is shown that in magnetohydrodynamics (MHD) with an ideal Ohm close-quote s law, in the presence of parallel heat flux, density gradient, temperature gradient, and parallel compression, but in the absence of perpendicular compressibility, there is an exact cancellation of the parallel transport terms. This cancellation is due to the fact that magnetic flux is advected in the presence of an ideal Ohm close-quote s law, and therefore parallel transport of temperature and density gives the same result as perpendicular advection of the same quantities. Discussions are also presented regarding parallel viscosity and parallel velocity shear, and the generalization to toroidal geometry. These results suggest that a correct generalization of the Hammett endash Perkins fluid operator [G. W. Hammett and F. W. Perkins, Phys. Rev. Lett. 64, 3019 (1990)] to simulate Landau damping for electromagnetic modes must give an operator that acts on the dynamics parallel to the perturbed magnetic field lines. copyright 1996 American Institute of Physics

Simultaneous removal of organic contaminants and heavy metals from kaolin using an upward electrokinetic soil remediation process

International Nuclear Information System (INIS)

Wang, J.-Y.; Huang, X.-J.; Kao, Jimmy C.M.; Stabnikova, Olena

2007-01-01

Kaolins contaminated with heavy metals, Cu and Pb, and organic compounds, p-xylene and phenanthrene, were treated with an upward electrokinetic soil remediation (UESR) process. The effects of current density, cathode chamber flushing fluid, treatment duration, reactor size, and the type of contaminants under the vertical non-uniform electric field of UESR on the simultaneous removal of the heavy metals and organic contaminants were studied. The removal efficiencies of p-xylene and phenanthrene were higher in the experiments with cells of smaller diameter or larger height, and with distilled water flow in the cathode chamber. The removal efficiency of Cu and Pb were higher in the experiments with smaller diameter or shorter height cells and 0.01 M HNO 3 solution as cathode chamber flow. In spite of different conditions for removal of heavy metals and organics, it is possible to use the upward electrokinetic soil remediation process for their simultaneous removal. Thus, in the experiments with duration of 6 days removal efficiencies of phenanthrene, p-xylene, Cu and Pb were 67%, 93%, 62% and 35%, respectively. The experiment demonstrated the feasibility of simultaneous removal of organic contaminants and heavy metals from kaolin using the upward electrokinetic soil remediation process

Technique of the biomechanical analysis of execution of upward jump piked

Directory of Open Access Journals (Sweden)

Nataliya Batieieva

2016-12-01

Full Text Available Purpose: the biomechanical analysis of execution of upward jump piked. Material & Methods: the following methods of the research were used: theoretical analysis and synthesis of data of special scientific and methodical literature; photographing, video filming, biomechanical computer analysis, pedagogical observation. Students (n=8 of the chair of national choreography of the department of choreographic art of Kiev national university of culture and art took part in carrying out the biomechanical analysis of execution of upward jump piked. Results: the biomechanical analysis of execution of upward jump piked is carried out, the kinematic characteristics (way, speed, acceleration, effort of the general center of weight (GCW and center of weight (CW of biolinks of body of the executor are received (feet, shins, hips, shoulder, forearm, hands. Biokinematic models (phases are constructed. Power characteristics are defined – mechanical work and kinetic energy of links of legs and hands at execution of upward jump piked. Conclusions: it is established that the technique of execution of upward jump piked considerably influences the level of technical training of the qualified sportsmen in gymnastics (sports, in aerobic gymnastics (aerobics, diving and dancing sports.

An Experiment Using Sucrose Density Gradients in the Undergraduate Biochemistry Laboratory.

Science.gov (United States)

Turchi, Sandra L.; Weiss, Monica

1988-01-01

Describes an experiment to be performed in an undergraduate biochemistry laboratory that is based on a gradient centrifugation system employing a simple bench top centrifuge, a freezer, and frozen surcose gradient solution to separate macromolecules and subcellular components. (CW)

Benchmarking of electrolyte mass transport in next generation lithium batteries

Directory of Open Access Journals (Sweden)

Jonas Lindberg

2017-12-01

Full Text Available Beyond conductivity and viscosity, little is often known about the mass transport properties of next generation lithium battery electrolytes, thus, making performance estimation uncertain when concentration gradients are present, as conductivity only describes performance in the absence of these gradients. This study experimentally measured the diffusion resistivity, originating from voltage loss due to a concentration gradient, together with the ohmic resistivity, obtained from ionic conductivity measurements, hence, evaluating electrolytes both with and without the presence of concentration gradients. Under galvanostatic conditions, the concentration gradients, of all electrolytes examined, developed quickly and the diffusion resistivity rapidly dominated the ohmic resistivity. The electrolytes investigated consisted of lithium salt in: room temperature ionic liquids (RTIL, RTIL mixed organic carbonates, dimethyl sulfoxide (DMSO, and a conventional Li-ion battery electrolyte. At steady state the RTIL electrolytes displayed a diffusion resistivity ~ 20 times greater than the ohmic resistivity. The DMSO-based electrolyte showed mass transport properties similar to the conventional Li-ion battery electrolyte. In conclusion, the results presented in this study show that the diffusion polarization must be considered in applications where high energy and power density are desired.

Regularized Regression and Density Estimation based on Optimal Transport

KAUST Repository

Burger, M.

2012-03-11

The aim of this paper is to investigate a novel nonparametric approach for estimating and smoothing density functions as well as probability densities from discrete samples based on a variational regularization method with the Wasserstein metric as a data fidelity. The approach allows a unified treatment of discrete and continuous probability measures and is hence attractive for various tasks. In particular, the variational model for special regularization functionals yields a natural method for estimating densities and for preserving edges in the case of total variation regularization. In order to compute solutions of the variational problems, a regularized optimal transport problem needs to be solved, for which we discuss several formulations and provide a detailed analysis. Moreover, we compute special self-similar solutions for standard regularization functionals and we discuss several computational approaches and results. © 2012 The Author(s).

Evaluation of the impact of density gradient centrifugation on fetal cell loss during enrichment from maternal peripheral blood.

Science.gov (United States)

Emad, Ahmed; Drouin, Régen

2014-09-01

Physical separation by density gradient centrifugation (DGC) is usually used as an initial step of multistep enrichment protocols for purification of fetal cells (FCs) from maternal blood. Many protocols were designed but no single approach was efficient enough to provide noninvasive prenatal diagnosis. Procedures and methods were difficult to compare because of the nonuniformity of protocols among different groups. Recovery of FCs is jeopardized by their loss during the process of enrichment. Any loss of FCs must be minimized because of the multiplicative effect of each step of the enrichment process. The main objective of this study was to evaluate FC loss caused by DGC. Fetal cells were quantified in peripheral blood samples obtained from both euploid and aneuploid pregnancies before and after enrichment by buoyant DGC using Histopaque 1.119 g/mL. Density gradient centrifugation results in major loss of 60% to 80% of rare FCs, which may further complicate subsequent enrichment procedures. Eliminating aggressive manipulations can significantly minimize FC loss. Data obtained raise questions about the appropriateness of the DGC step for the enrichment of rare FCs and argues for the use of the alternative nonaggressive version of the procedure presented here or prioritizing other methods of enrichments. © 2014 John Wiley & Sons, Ltd.

Effects of fueling profiles on plasma transport

International Nuclear Information System (INIS)

Mense, A.T.; Houlberg, W.A.; Attenberger, S.E.; Milora, S.L.

1978-04-01

A one-dimensional (1-D), multifluid transport model is used to investigate the effects of particle fueling profiles on plasma transport in an ignition-sized tokamak (TNS). Normal diffusive properties of plasmas will likely maintain the density at the center of the discharge even if no active fueling is provided there. This significantly relaxes the requirements for fuel penetration. Not only is lower fuel penetration easier to achieve, but it may have the advantage of reducing or eliminating density gradient-driven trapped particle microinstabilities. Simulation of discrete pellet fueling indicates that relatively low velocity (approximately 10 3 m/sec) pellets may be sufficient to fuel a TNS-sized device (approximately 1.25-m minor radius), to produce a relatively broad, cool edge region of plasma which should reduce the potential for sputtering, and also to reduce the likelihood of trapped particle mode dominated transport. Low penetrating pellets containing up to 10 to 20 percent of the total plasma ions can produce fluctuations in density and temperature at the plasma edge, but the pressure profile and fusion alpha production remain almost constant

Transport of light, trace impurities in Alcator C-Mod

Science.gov (United States)

Rowan, W. L.; Bespamyatnov, I. O.; Liao, K. T.; Horton, W.; Fu, X. R.; Hughes, J. W.

2012-10-01

Light impurity profiles for boron were measured in ITB, H-mode, L-mode, and I-mode discharges in Alcator C-Mod. Within this wide range of modes, the profiles varied from peaked to hollow to flat. Specifically, hollow profiles are often observed in H-mode, while ITBs produce strong peaking, and L-mode produces moderate peaking. I-mode discharges are characterized by flat impurity profiles. For the study reported here, the profiles were measured with charge exchange recombination spectroscopy. The dependences of Rv/D were sought on dimensionless quantities including ion density scale length, effective charge, collisionality, and temperature scale length. We find that neoclassical transport consistently underestimates the measured transport. The excess measured transport is assumed to be turbulent. The strongest dependence of Rv/D is with temperature scale length. In addition, the measured transport was compared with the prediction of an analytical theory of drift wave turbulence that identifies transport implications for drift waves driven by ion and impurity density gradients.

Drift-Alfven wave mediated particle transport in an elongated density depression

International Nuclear Information System (INIS)

Vincena, Stephen; Gekelman, Walter

2006-01-01

Cross-field particle transport due to drift-Alfven waves is measured in an elongated density depression within an otherwise uniform, magnetized helium plasma column. The depression is formed by drawing an electron current to a biased copper plate with cross-field dimensions of 28x0.24 ion sound-gyroradii ρ s =c s /ω ci . The process of density depletion and replenishment via particle flux repeats in a quasiperiodic fashion for the duration of the current collection. The mode structure of the wave density fluctuations in the plane perpendicular to the background magnetic field is revealed using a two-probe correlation technique. The particle flux as a function of frequency is measured using a linear array of Langmuir probes and the only significant transport occurs for waves with frequencies between 15%-25% of the ion cyclotron frequency (measured in the laboratory frame) and with perpendicular wavelengths k perpendicular ρ s ∼0.7. The frequency-integrated particle flux is in rough agreement with observed increases in density in the center of the depletion as a function of time. The experiments are carried out in the Large Plasma Device (LAPD) [Gekelman et al., Rev. Sci. Instrum. 62, 2875 (1991)] at the Basic Plasma Science Facility located at the University of California, Los Angeles

On the mechanism of charge transport in low density polyethylene

Science.gov (United States)

Upadhyay, Avnish K.; Reddy, C. C.

2017-08-01

Polyethylene based polymeric insulators, are being increasingly used in the power industry for their inherent advantages over conventional insulation materials. Specifically, modern power cables are almost made with these materials, replacing the mass-impregnated oil-paper cable technology. However, for ultra-high dc voltage applications, the use of these polymeric cables is hindered by ununderstood charge transport and accumulation. The conventional conduction mechanisms (Pool-Frenkel, Schottky, etc.) fail to track high-field charge transport in low density polyethylene, which is semi-crystalline in nature. Until now, attention was devoted mainly to the amorphous region of the material. In this paper, authors propose a novel mechanism for conduction in low density polyethylene, which could successfully track experimental results. As an implication, a novel, substantial relationship is established for electrical conductivity that could be effectively used for understanding conduction and breakdown in polyethylene, which is vital for successful development of ultra-high voltage dc cables.

Lactate uptake against a concentration gradient

DEFF Research Database (Denmark)

Nordström, Carl-Henrik; Nielsen, Troels Halfeld; Nielsen, Hans Boye

2014-01-01

The recently published article by Jalloh et al (Jalloh I, Helmy A, Shannon RJ, Gallagher CN, Menon D, Carpenter K, Hutchinson P. Lactate uptake by the injured human brain - evidence from an arterio-venous gradient and cerebral microdialysis study. J Neurotrauma. 2013 Aug 22. [Epub ahead of print......]) concludes that lactate may be transported across the blood brain barrier into the brain against a concentration gradient. Unfortunately the authors have misinterpreted the concept of analytical imprecision and their conclusion is based on analytical artifact. As the topic of lactate transport into the brain...

Upwards Intensifiers in the English, German and Croatian Language

Directory of Open Access Journals (Sweden)

Anita Pavić Pintarić

2014-12-01

Full Text Available This paper investigates the upwards intensifiers (adverbs of intensifying in the English, German and Croatian language. Intensity as an important human cognitive category, and language expressivity is differently treated in grammars and dictionaries of all three languages, especially with respect to different degrees of intensity. In this paper we argue that it is possible to model a typology of upwards adverb intensifiers in the three languages, according to their morphosyntactic and semantic aspects. When it comes to intensifiers, it is necessary to describe which collocates are modified by intensifiers and which semantic fields the collocates belong to. The results of the corpus analysis based on Harry Potter novels show that all the three languages express the category of the upwards intensity in the same way: the number of intensifiers is similar, the collocates mostly belong to the same semantic fields and word classes, they have similar syntactic functions.

Gyrokinetic particle simulation of neoclassical transport

International Nuclear Information System (INIS)

Lin, Z.; Tang, W.M.; Lee, W.W.

1995-01-01

A time varying weighting (δf ) scheme for gyrokinetic particle simulation is applied to a steady-state, multispecies simulation of neoclassical transport. Accurate collision operators conserving momentum and energy are developed and implemented. Simulation results using these operators are found to agree very well with neoclassical theory. For example, it is dynamically demonstrated that like-particle collisions produce no particle flux and that the neoclassical fluxes are ambipolar for an ion--electron plasma. An important physics feature of the present scheme is the introduction of toroidal flow to the simulations. Simulation results are in agreement with the existing analytical neoclassical theory. The poloidal electric field associated with toroidal mass flow is found to enhance density gradient-driven electron particle flux and the bootstrap current while reducing temperature gradient-driven flux and current. Finally, neoclassical theory in steep gradient profile relevant to the edge regime is examined by taking into account finite banana width effects. In general, in the present work a valuable new capability for studying important aspects of neoclassical transport inaccessible by conventional analytical calculation processes is demonstrated. copyright 1995 American Institute of Physics

Energy and particle core transport in tokamaks and stellarators compared

Energy Technology Data Exchange (ETDEWEB)

Beurskens, Marc; Angioni, Clemente; Beidler, Craig; Dinklage, Andreas; Fuchert, Golo; Hirsch, Matthias; Puetterich, Thomas; Wolf, Robert [Max-Planck-Institut fuer Plasmaphysik, Greifswald/Garching (Germany)

2016-07-01

The paper discusses expectations for core transport in the Wendelstein 7-X stellarator (W7-X) and presents a comparison to tokamaks. In tokamaks, the neoclassical trapped-particle-driven losses are small and turbulence dominates the energy and particle transport. At reactor relevant low collisionality, the heat transport is limited by ion temperature gradient limited turbulence, clamping the temperature gradient. The particle transport is set by an anomalous inward pinch, yielding peaked profiles. A strong edge pedestal adds to the good confinement properties. In traditional stellarators the 3D geometry cause increased trapped orbit losses. At reactor relevant low collisionality and high temperatures, these neoclassical losses would be well above the turbulent transport losses. The W7-X design minimizes neoclassical losses and turbulent transport can become dominant. Moreover, the separation of regions of bad curvature and that of trapped particle orbits in W7-X may have favourable implications on the turbulent electron heat transport. The neoclassical particle thermodiffusion is outward. Without core particle sources the density profile is flat or even hollow. The presence of a turbulence driven inward anomalous particle pinch in W7-X (like in tokamaks) is an open topic of research.

Particle and solute migration in porous media. Modeling of simultaneous transport of clay particles and radionuclides in a salinity gradient

International Nuclear Information System (INIS)

Faure, M.H.

1994-03-01

Understanding the mechanisms which control the transient transport of particles and radionuclides in natural and artificial porous media is a key problem for the assessment of safety of radioactive waste disposals. An experimental study has been performed to characterize the clayey particle mobility in porous media: a laboratory- made column, packed with an unconsolidated sand bentonite (5% weight) sample, is flushed with a salt solution. An original method of salinity gradient allowed us to show and to quantify some typical behaviours of this system: threshold effects in the peptization of particles, creation of preferential pathways, formation of immobile water zones induce solute-transfer limitation. The mathematical modelling accounts for a phenomenological law, where the distribution of particles between the stagnant water zone and the porous medium is a function of sodium chloride concentration. This distribution function is associated with a radionuclide adsorption model, and is included in a convective dispersive transport model with stagnant water zones. It allowed us to simulate the particle and solute transport when the salt environment is modified. The complete model has been validated with experiments involving cesium, calcium and neptunium in a sodium chloride gradient. (author). refs., figs., tabs

Transport through correlated systems with density functional theory.

Science.gov (United States)

Kurth, S; Stefanucci, G

2017-10-18

We present recent advances in density functional theory (DFT) for applications in the field of quantum transport, with particular emphasis on transport through strongly correlated systems. We review the foundations of the popular Landauer-Büttiker(LB)  +  DFT approach. This formalism, when using approximations to the exchange-correlation (xc) potential with steps at integer occupation, correctly captures the Kondo plateau in the zero bias conductance at zero temperature but completely fails to capture the transition to the Coulomb blockade (CB) regime as the temperature increases. To overcome the limitations of LB  +  DFT, the quantum transport problem is treated from a time-dependent (TD) perspective using TDDFT, an exact framework to deal with nonequilibrium situations. The steady-state limit of TDDFT shows that in addition to an xc potential in the junction, there also exists an xc correction to the applied bias. Open shell molecules in the CB regime provide the most striking examples of the importance of the xc bias correction. Using the Anderson model as guidance we estimate these corrections in the limit of zero bias. For the general case we put forward a steady-state DFT which is based on one-to-one correspondence between the pair of basic variables, steady density on and steady current across the junction and the pair local potential on and bias across the junction. Like TDDFT, this framework also leads to both an xc potential in the junction and an xc correction to the bias. Unlike TDDFT, these potentials are independent of history. We highlight the universal features of both xc potential and xc bias corrections for junctions in the CB regime and provide an accurate parametrization for the Anderson model at arbitrary temperatures and interaction strengths, thus providing a unified DFT description for both Kondo and CB regimes and the transition between them.

Cover Art: River's Edge: Downward, Outward, Upward

Directory of Open Access Journals (Sweden)

Jonee Kulman Brigham

2017-10-01

Full Text Available Artist's Statement for the cover art of IJPS volume 4, issue 3: River's Edge: Downward, Outward, Upward, 2015. Mixed Media: photograph, inkjet printed on presentation matte of colored pencil over photograph.

Quasilinear Carbon Transport In An Impurity Hole Plasma In LHD

Energy Technology Data Exchange (ETDEWEB)

Mikkelsen, David R. [PPPL; Tanaka, K. [NIFS; Nunami, M. [NIFS; Watanabe, T-H. [Nagoya University; Sugama, H. [NIFS; Yoshinuma, M. [NIFS; Suzuki, Y. [NIFS; Goto, M. [NIFS; Morita, S. [NIFS; Wieland, B. [NIFS; Yamada, I. [NIFS; Yashura, R. [NIFS; Akiyama, T. [NIFS; Pablant, Novimir A. [PPPL

2014-04-01

Comprehensive electrostatic gyrokinetic linear stability calculations for ion-scale microinstabilities in an LHD plasma with an ion-ITB and carbon "impurity hole" are used to make quasilinear estimates of particle flux to explore whether microturbulence can explain the observed outward carbon fluxes that flow "up" the impurity density gradient. The ion temperature is not stationary in the ion-ITB phase of the simulated discharge, during which the core carbon density decreases continuously. To fully sample these varying conditions the calculations are carried out at three radial locations and four times. The plasma parameter inputs are based on experimentally measured profiles of electron and ion temperature, as well as electron and carbon density. The spectroscopic line-average ratio of hydrogen and helium densities is used to set the density of these species. Three ion species (H,He,C) and the electrons are treated kinetically, including collisions. Electron instability drive does enhance the growth rate significantly, but the most unstable modes have characteristics of ion temperature gradient (ITG) modes in all cases. As the carbon density gradient is scanned between the measured value and zero, the quasilinear carbon flux is invariably inward when the carbon density profile is hollow, so turbulent transport due to the instabilities considered here does not explain the observed outward flux of impurities in impurity hole plasmas. The stiffness of the quasilinear ion heat flux is found to be 1.7-2.3, which is lower than several estimates in tokamaks.

Development of gradient-corrected exchange-correlation functionals in the density functional theory; Developpement de fonctionnelles corrigees du gradient en theorie de la fonctionnelle de la densite

Energy Technology Data Exchange (ETDEWEB)

Lembarki, A.

1994-12-01

In this work, we have developed some gradient-corrected exchange-correlation functionals. This study is in keeping with the density functional theory (DFT) formalism. In the first part of this memory, a description of Hartree-Fock (HF), post-HF and density functional theories is given. The second part is devoted the study the different approximations of DFT exchange-correlation functionals which have been proposed in the last years. In particular, we have underlined the approximations used for the construction of these functionals. The third part of this memory consists in the development of new gradient-corrected functionals. In this study, we have established a new relation between exchange energy, correlation energy and kinetic energy. We have deduced two new possible forms of exchange or correlation functionals, respectively. In the fourth part, we have studied the exchange potential, for which the actual formulation does not satisfy some theoretical conditions, such as the asymptotic behavior -1/r. Our contribution lies in the development of an exchange potential with a correct asymptotic -1/r behavior for large values of r. In this chapter, we have proposed a model which permits the obtention of the exchange energy from the exchange potential, using the virial theorem. The fifth part of this memory is devoted the application of these different functionals to simple systems (H{sub 2}O, CO, N{sub 2}O, H{sub 3}{sup +} and H{sub 5}{sup +}) in order to characterize the performance of DFT calculations in regards to those obtained with post-HF methods. (author). 215 refs., 8 figs., 28 tabs.

Electric field and transport in W7-AS

International Nuclear Information System (INIS)

Kick, M.; Maassberg, H.; Anton, M.; Baldzuhn, J.; Endler, M.; Goerner, C.; Hirsch, M.; Weller, A.; Zoletnik, S.

1999-01-01

At W7-AS, confinement properties are analysed and compared mainly with neoclassical predictions for quite different conditions. Low-density electron cyclotron resonance heating (ECRH) discharges allow access to the very-long-mean-free-path regime for electrons (T e up to 6 keV) whereas pure neutral beam injections (NBI) and combined NBI/ECRH discharges at high density (T i approx. T e ≥ 1 keV at n e approx. 10 20 m -3 ) lead to high performance (τ B up to 50 ms). Depending on the achieved temperatures, the experimental transport analysis in the plasma core is consistent with the neoclassical predictions. The experimentally observed 'electron root' feature with strong E r >0 is driven by the convective flux of ripple-trapped suprathermal electrons generated by the ECRH absorption. 'Optimum' confinement is obtained in discharges with narrow density, but broad temperature profiles with steep gradients in the region of low densities and strong E r <0 close to the plasma edge. The large radial electric fields, both positive and negative, strongly reduce neoclassical transport. The achieved temperatures, however, are limited by the strong temperature dependence of the neoclassical transport. (author)

Modelling larval transport in a axial convergence front

Science.gov (United States)

Robins, P.

2010-12-01

Marine larvae exhibit different vertical swimming behaviours, synchronised by factors such as tidal currents and daylight, in order to aid retention near the parent populations and hence promote production, avoid predation, or to stimulate digestion. This paper explores two types of larval migration in an estuarine axial convergent front which is an important circulatory mechanism in many coastal regions where larvae are concentrated. A parallelised, three-dimensional, ocean model was applied to an idealised estuarine channel which was parameterised from observations of an axial convergent front which occurs in the Conwy Estuary, U.K. (Nunes and Simpson, 1985). The model successfully simulates the bilateral cross-sectional recirculation of an axial convergent front, which has been attributed to lateral density gradients established by the interaction of the lateral shear of the longitudinal currents with the axial salinity gradients. On the flood tide, there is surface axial convergence whereas on the ebb tide, there is (weaker) surface divergence. Further simulations with increased/decreased tidal velocities and with stronger/weaker axial salinity gradients are planned so that the effects of a changing climate on the secondary flow can be understood. Three-dimensional Lagrangian Particle Tracking Models (PTMs) have been developed which use the simulated velocity fields to track larvae in the estuarine channel. The PTMs take into account the vertical migrations of two shellfish species that are commonly found in the Conwy Estuary: (i) tidal migration of the common shore crab (Carcinus maenas) and (ii), diel (daily) migration of the Great scallop (Pecten maximus). These migration behaviours are perhaps the most widespread amongst shellfish larvae and have been compared with passive (drifting) particles in order to assess their relative importance in terms of larval transport. Preliminary results suggest that the net along-estuary dispersal over a typical larval

Effects of intergroup upward comparison, trait self-esteem, and identity shift on state self-esteem and affect in upward comparison with in-group members

OpenAIRE

Isobe, Chikae; Ura, Mitsuhiro

2006-01-01

The present study investigated factors that protect people low in trait self-esteem (Low-SEs), who may be less skilled at constructing information in self-enhancing manners, from threats after interpersonal upward comparison with in-group members. We hypothesized that even Low-SEs can maintain their state self-esteem under intergroup upward comparison. Furthermore, this study explored the possibility that individuals used identity-shift, a strategy to maintain their personal identity, even in...

Density-based and transport-based core-periphery structures in networks.

Science.gov (United States)

Lee, Sang Hoon; Cucuringu, Mihai; Porter, Mason A

2014-03-01

Networks often possess mesoscale structures, and studying them can yield insights into both structure and function. It is most common to study community structure, but numerous other types of mesoscale structures also exist. In this paper, we examine core-periphery structures based on both density and transport. In such structures, core network components are well-connected both among themselves and to peripheral components, which are not well-connected to anything. We examine core-periphery structures in a wide range of examples of transportation, social, and financial networks-including road networks in large urban areas, a rabbit warren, a dolphin social network, a European interbank network, and a migration network between counties in the United States. We illustrate that a recently developed transport-based notion of node coreness is very useful for characterizing transportation networks. We also generalize this notion to examine core versus peripheral edges, and we show that the resulting diagnostic is also useful for transportation networks. To examine the properties of transportation networks further, we develop a family of generative models of roadlike networks. We illustrate the effect of the dimensionality of the embedding space on transportation networks, and we demonstrate that the correlations between different measures of coreness can be very different for different types of networks.

Aberrant Bone Density in Aging Mice Lacking the Adenosine Transporter ENT1

Science.gov (United States)

Hinton, David J.; McGee-Lawrence, Meghan E.; Lee, Moonnoh R.; Kwong, Hoi K.; Westendorf, Jennifer J.; Choi, Doo-Sup

2014-01-01

Adenosine is known to regulate bone production and resorption in humans and mice. Type 1 equilibrative nucleoside transporter (ENT1) is responsible for the majority of adenosine transport across the plasma membrane and is ubiquitously expressed in both humans and mice. However, the contribution of ENT1-mediated adenosine levels has not been studied in bone remodeling. With the recent identification of the importance of adenosine signaling in bone homeostasis, it is essential to understand the role of ENT1 to develop novel therapeutic compounds for bone disorders. Here we examined the effect of ENT1 deletion on bone density using X-ray, dual energy X-ray absorptiometry and micro-computerized tomography analysis. Our results show that bone density and bone mineral density is reduced in the lower thoracic and lumbar spine as well as the femur of old ENT1 null mice (>7 months) compared to wild-type littermates. Furthermore, we found increased mRNA expression of tartrate-resistant acid phosphatase (TRAP), an osteoclast marker, in isolated long bones from 10 month old ENT1 null mice compared to wild-type mice. In addition, aged ENT1 null mice displayed severe deficit in motor coordination and locomotor activity, which might be attributed to dysregulated bone density. Overall, our study suggests that ENT1-regulated adenosine signaling plays an essential role in lumbar spine and femur bone density. PMID:24586402

Aberrant bone density in aging mice lacking the adenosine transporter ENT1.

Directory of Open Access Journals (Sweden)

David J Hinton

Full Text Available Adenosine is known to regulate bone production and resorption in humans and mice. Type 1 equilibrative nucleoside transporter (ENT1 is responsible for the majority of adenosine transport across the plasma membrane and is ubiquitously expressed in both humans and mice. However, the contribution of ENT1-mediated adenosine levels has not been studied in bone remodeling. With the recent identification of the importance of adenosine signaling in bone homeostasis, it is essential to understand the role of ENT1 to develop novel therapeutic compounds for bone disorders. Here we examined the effect of ENT1 deletion on bone density using X-ray, dual energy X-ray absorptiometry and micro-computerized tomography analysis. Our results show that bone density and bone mineral density is reduced in the lower thoracic and lumbar spine as well as the femur of old ENT1 null mice (>7 months compared to wild-type littermates. Furthermore, we found increased mRNA expression of tartrate-resistant acid phosphatase (TRAP, an osteoclast marker, in isolated long bones from 10 month old ENT1 null mice compared to wild-type mice. In addition, aged ENT1 null mice displayed severe deficit in motor coordination and locomotor activity, which might be attributed to dysregulated bone density. Overall, our study suggests that ENT1-regulated adenosine signaling plays an essential role in lumbar spine and femur bone density.

Cell kinetics of differentiation of Na+-dependent hexose transport in a cultured renal epithelial cell line

International Nuclear Information System (INIS)

Cook, J.S.; Weiss, E.R.

1985-01-01

Fully differentiated cells of the renal proximal tubule have the capability of taking up hexoses across their apical borders by transport coupled to the Na + -electrochemical gradient. This property is also found in postconfluent cultures of the cloned cell line LLC-PK 1 , a morphologically polarized line of renal cells. Postconfluent cells develop the Na + -dependent capacity to transport hexoses at their apical surface. This function is not observable during the growth phase of the cultures. To analyze the developmental process at the cellular level a method has been derived to separate transporting cells, expressing the differentiated function, from nontransporting cells. The method is based on the swelling of the cells accompanying the uptake of the nonmetabolizable glucose analog alpha methylglucoside. The swollen cells have a lower buoyant density than the undifferentiated cells and may be separated from them on density gradients. Analysis of the distribution of cells on such gradients shows that after the cells reach confluence the undifferentiated subpopulation is recruited onto the differentiation pathway with a rate constant of 0.2 per day, that 5 to 7 days are required for a cell to traverse this pathway to the fully differentiated state, and that once the maximum uptake capacity is achieved the cells do not develop further

Turbulent momentum transport due to neoclassical flows

International Nuclear Information System (INIS)

Lee, Jungpyo; Barnes, Michael; Parra, Felix I; Belli, Emily; Candy, Jeff

2015-01-01

Intrinsic toroidal rotation in a tokamak can be driven by turbulent momentum transport due to neoclassical flow effects breaking a symmetry of turbulence. In this paper we categorize the contributions due to neoclassical effects to the turbulent momentum transport, and evaluate each contribution using gyrokinetic simulations. We find that the relative importance of each contribution changes with collisionality. For low collisionality, the dominant contributions come from neoclassical particle and parallel flows. For moderate collisionality, there are non-negligible contributions due to neoclassical poloidal electric field and poloidal gradients of density and temperature, which are not important for low collisionality. (paper)

Particle and solute migration in porous media. Modeling of simultaneous transport of clay particles and radionuclides in a salinity gradient; Migration de particules et de solutes en milieu poreux. Modelisation du transport simultane de particules argileuses et de radionucleides sous l`effet d`un gradient de salinite

Energy Technology Data Exchange (ETDEWEB)

Faure, M H

1994-03-01

Understanding the mechanisms which control the transient transport of particles and radionuclides in natural and artificial porous media is a key problem for the assessment of safety of radioactive waste disposals. An experimental study has been performed to characterize the clayey particle mobility in porous media: a laboratory- made column, packed with an unconsolidated sand bentonite (5% weight) sample, is flushed with a salt solution. An original method of salinity gradient allowed us to show and to quantify some typical behaviours of this system: threshold effects in the peptization of particles, creation of preferential pathways, formation of immobile water zones induce solute-transfer limitation. The mathematical modelling accounts for a phenomenological law, where the distribution of particles between the stagnant water zone and the porous medium is a function of sodium chloride concentration. This distribution function is associated with a radionuclide adsorption model, and is included in a convective dispersive transport model with stagnant water zones. It allowed us to simulate the particle and solute transport when the salt environment is modified. The complete model has been validated with experiments involving cesium, calcium and neptunium in a sodium chloride gradient. (author). refs., figs., tabs.

Nonlinear neoclassical transport in toroidal edge plasmas

International Nuclear Information System (INIS)

Fueloep, T.

2002-01-01

Edge plasma processes play a critical role for the global confinement of the plasma in a tokamak. In the edge region, where impurity ions are abundant and the temperature and density gradients are large, the assumptions of standard neoclassical theory break down. This paper reviews recent extensions of neoclassical theory to treat this problem, in particular our own work, which focuses on the nonlinear aspects of transport in a plasma with heavy impurity ions. In this theory, the pressure and temperature gradients are allowed to be steeper than in conventional theory neoclassical theory, so that the friction force between the bulk ions and heavy impurities is comparable to the parallel impurity pressure gradient. The impurity ions are then found to undergo a spontaneous rearrangement on each flux surface. This reduces their parallel friction with the bulk ions and causes the neoclassical ion flux to become a non-monotonic function of the gradients for plasma parameters typical of the tokamak edge. Thus, the neoclassical confinement is improved in regions where the gradients are large, such as in the edge pedestal. (orig.)

Two-phase upward air water flow in a prismatic channel with rectangular base

International Nuclear Information System (INIS)

Carvalho Tofani, P. de

1984-01-01

Two-phase liquid-gas mixtures provide suitable means to simulate water-water vapor flows, which may occur in nuclear reactor cores. The mastery of physical transport phenomena is of great importance, as far as the analysis of such thermal systems is concerned. Within the framework of thermal-hydraulic programs, experiments have been carried out to investigate the two-phase upward air-water flow structure, in a rectangular test section, by using independent measuring techniques, which comprise direct viewing and photography, electrical probes and gamma-ray attenuation. In this paper, flow pattern maps and correlations for flow pattern transitions, void fraction profiles, liquid film thickness and superficial average void fraction are proposed and compared to available data. (Author) [pt

Preparation of TiC/Ni3Al Composites by Upward Melt Infiltration

Institute of Scientific and Technical Information of China (English)

无

2000-01-01

TiC/Ni3Al composites have been prepared using upward infiltration method. The densificstion was performed by both Ni3Al melt filling and TiC sintering during the infiltration. The dissolution of TiC in liquid Ni3Al has been evidenced by finding Ni3(Al,Ti)C after fast cooling in the TiC/Ni3Al composites. The dissolution may be responsible for the infiltration and sintering. Compared with downward infiltration, the upward infiltration brought about higher strength and fracture toughness and shorter infiltration time. TiC/20 vol. pct Ni3Al composite processed by upward infiltration had a flexural strength of 1476 Mpa with a statistic Weibull modulus of 20.2 and a fracture toughness of 20.4 Mpa(m). Better mechanical properties may be attributed to melt unidirectional movement in upward infiltration.

Non-diffusive transport in 3-D pressure driven plasma turbulence

International Nuclear Information System (INIS)

Del-Castillo-Negrete, D.; Carreras, B.A.; Lynch, V.

2005-01-01

Numerical evidence of non-diffusive transport in 3-dimensional, resistive, pressure-gradient-driven plasma turbulence is presented. It is shown that the probability density function (pdf) of tracers is strongly non-Gaussian and exhibits algebraic decaying tails. To describe these results, a transport model using fractional derivative operators in proposed. The model incorporates in a unified way non-locality (i.e., non-Fickian transport), memory effects (i.e., non-Markovian transport), and non-diffusive scaling features known to be present in fusion plasmas. There is quantitative agreement between the model and the turbulent transport numerical calculations. In particular, the model reproduces the shape and space-time scaling of the pdf, and the super-diffusive scaling of the moments. (author)

Critical temperature gradient length signatures in heat wave propagation across internal transport barriers in the Joint European Torus

International Nuclear Information System (INIS)

Casati, Alessandro; Mantica, P.; Eester, D. van; Hawkes, N.; De Vries, P.; Imbeaux, F.; Joffrin, E.; Marinoni, A.; Ryter, F.; Salmi, A.; Tala, T.

2007-01-01

New results on electron heat wave propagation using ion cyclotron resonance heating power modulation in the Joint European Torus (JET) [P. H. Rebut et al., Nucl. Fusion 25, 1011 (1985)] plasmas characterized by internal transport barriers (ITBs) are presented. The heat wave generated outside the ITB, and traveling across it, always experiences a strong damping in the ITB layer, demonstrating a low level of transport and loss of stiffness. In some cases, however, the heat wave is strongly inflated in the region just outside the ITB, showing features of convective-like behavior. In other cases, a second maximum in the perturbation amplitude is generated close to the ITB foot. Such peculiar types of behavior can be explained on the basis of the existence of a critical temperature gradient length for the onset of turbulent transport. Convective-like features appear close to the threshold (i.e., just outside the ITB foot) when the value of the threshold is sufficiently high, with a good match with the theoretical predictions for the trapped electron mode threshold. The appearance of a second maximum is due to the oscillation of the temperature profile across the threshold in the case of a weak ITB. Simulations with an empirical critical gradient length model and with the theory based GLF23 [R. E. Waltz et al., Phys. Plasmas, 4, 2482 (1997)] model are presented. The difference with respect to previous results of cold pulse propagation across JET ITBs is also discussed

A case study of lightning attachment to flat ground showing multiple unconnected upward leaders

Science.gov (United States)

Cummins, Kenneth L.; Krider, E. Philip; Olbinski, Mike; Holle, Ronald L.

2018-04-01

On 10 July 2015, a cloud-to-ground (CG) lightning flash that produced two ground terminations was photographed from inside the safety of a truck in southern New Mexico. An analysis of archived NLDN data verified that this was a two-stroke flash, and a close-up view of the first stroke shows that it also initiated at least 12 unconnected, upward leaders (or "streamers") near the ground termination. No unconnected upward leaders were seen near the second ground attachment. After combining an analysis of the photograph with information provided by the NLDN, we infer that the first stroke was of negative (normal) polarity, had modest peak current, and struck about 460 m (± 24%) from the camera. Attachment occurred when an upward-propagating positive leader reached an inferred height of about 21 m above local ground. The second stroke struck ground about 740 m from the camera, and the height of its attachment leader is estimated to be 15 m. The estimated lengths of the unconnected upward leaders in the two-dimensional (2-D) plane of the first stroke range from 2 to 8 m, and all appear to be located within 15 m (2-D) of the main ground termination, with 24% uncertainty. Many of the unconnected upward leaders (inferred to be positive) exhibit multiple upward branches, and most of those branches have upward-directed forks or splits at their ends. This is the first report showing such extensive branching for positive upward leaders in natural lightning strikes to ground. None of the upward leaders can be seen to emanate from the tops of tall, isolated, or pointed objects on the ground, but they likely begin on small plants and rocks, or flat ground. In terms of lightning safety, this photo demonstrates that numerous upward leaders can be produced near a lightning strike point and have the potential to damage or cause injury at more than one specific point on the ground.

Gram-scale fractionation of nanodiamonds by density gradient ultracentrifugation

KAUST Repository

Peng, Wei

2013-01-01

Size is a defining characteristic of nanoparticles; it influences their optical and electronic properties as well as their interactions with molecules and macromolecules. Producing nanoparticles with narrow size distributions remains one of the main challenges to their utilization. At this time, the number of practical approaches to optimize the size distribution of nanoparticles in many interesting materials systems, including diamond nanocrystals, remains limited. Diamond nanocrystals synthesized by detonation protocols-so-called detonation nanodiamonds (DNDs)-are promising systems for drug delivery, photonics, and composites. DNDs are composed of primary particles with diameters mainly <10 nm and their aggregates (ca. 10-500 nm). Here, we introduce a large-scale approach to rate-zonal density gradient ultracentrifugation to obtain monodispersed fractions of nanoparticles in high yields. We use this method to fractionate a highly concentrated and stable aqueous solution of DNDs and to investigate the size distribution of various fractions by dynamic light scattering, analytical ultracentrifugation, transmission electron microscopy and powder X-ray diffraction. This fractionation method enabled us to separate gram-scale amounts of DNDs into several size ranges within a relatively short period of time. In addition, the high product yields obtained for each fraction allowed us to apply the fractionation method iteratively to a particular size range of particles and to collect various fractions of highly monodispersed primary particles. Our method paves the way for in-depth studies of the physical and optical properties, growth, and aggregation mechanism of DNDs. Applications requiring DNDs with specific particle or aggregate sizes are now within reach. © 2013 The Royal Society of Chemistry.

Survival of Ucides cordatus (Decapoda: Ocypodidae megalopae during transport under different conditions of density and duration

Directory of Open Access Journals (Sweden)

Robson Ventura

2010-01-01

Full Text Available Target areas for Ucides cordatus (Linnaeus, 1763 restocking programs are often located far from the laboratory where larval rearing is developed. During translocation, the larvae are submitted to highly stressful conditions due to handling, packing, and transport activities. The aim of the present study was to assess the mortality rates of U. cordatus megalopae caused by different transportation procedures. Megalopae at loading densities of 50, 150, and 300 ind.L-1 were packed in double polyethylene 12 x 25 cm plastic bags with 200 ml of marine water at salinity 30. The bags were filled with oxygen at a proportion of 1:2 parts of water and sealed tightly. The trepidations during transport were simulated by the use of a shaker device (800 vibrations/minute over periods of three and six hours inside a dark container. The survivorship rates of larvae after simulation were compared to those obtained in control groups, which consisted of plastic vials with megalopae at a loading density of 50 ind.L-1 maintained at rest. Immediately after the two transport simulations, there was no significant difference in survivorship between the treatments and the control. However, 24 hours after simulation some of the tested densities resulted in significantly lower survivorships. The results demonstrated that U. cordatus megalopae can tolerate six hours of shaking during transportation, at high densities with minimal mortality.

Temperature Gradients on the Cell Wall in the Critical Viscosity Experiment

Science.gov (United States)

Berg, Robert F.; Moldover, Michael R.

1993-01-01

Because of the diverging susceptibility delta rho/delta Tau near the liquid-vapor critical point, temperature gradients must be kept small to maintain adequate sample homogeneity. In our Science Requirements Document we paid particular attention to radial density gradients caused by equilibration of the xenon sample. Axial density gradients were addressed through the requirement that the cell's copper wall have a gradient less than 22 microK/m. This report re-examines the cell wall's temperature distribution in more detail by estimating all known significant contributions to temperature differences on the cell's wall.

Density profile analysis during an ELM event in ASDEX Upgrade H-modes

International Nuclear Information System (INIS)

Nunes, I.; Manso, M.; Serra, F.; Horton, L.D.; Conway, G.D.; Loarte, A.

2005-01-01

This paper reports results on measurements of the density profiles. Here we analyse the behaviour of the electron density for a set of experiments in type I ELMy H-mode discharges in ASDEX Upgrade where the plasma current, plasma density, triangularity and input power were varied. Detailed measurements of the radial extent of the perturbation on the density profiles caused by the edge localized mode (ELM) crash (ELM affected depth), the velocity of the radial propagation of the perturbation as well as the width and gradient of the density pedestal are determined. The effect of a type I ELM event on the density profiles affects the outermost 20-40% of the plasma minor radius. At the scrape-off layer (SOL) the density profile broadens while in the pedestal region the density decreases resulting in a smaller density gradient. This change in the density profile defines a pivot point around which the density profile changes. The average radial velocity at the SOL is in the range 125-150 ms -1 and approximately constant for all the density layers far from the pivot point. The width of the density pedestal is approximately constant for all the ELMy H-mode discharges analysed, with values between 2 and 3.5 cm. These results are then compared with an analytical model where the width of the density is predominantly set by ionization (neutral penetration model). The width of the density profiles for L-mode discharges is included, since L- and H-mode have different particle transport. No agreement between the experimental results and the model is found

Physics basis of Multi-Mode anomalous transport module

Energy Technology Data Exchange (ETDEWEB)

Rafiq, T.; Kritz, A. H.; Luo, L. [Department of Physics, Lehigh University, Bethlehem, Pennsylvania 18015 (United States); Weiland, J. [Departments of Applied Physics, Chalmers University of Technology and Euratom-VR Assoc., S41296 Gothenburg (Sweden); Pankin, A. Y. [Tech-X Corporation, Boulder, Colorado (United States)

2013-03-15

The derivation of Multi-Mode anomalous transport module version 8.1 (MMM8.1) is presented. The MMM8.1 module is advanced, relative to MMM7.1, by the inclusion of peeling modes, dependence of turbulence correlation length on flow shear, electromagnetic effects in the toroidal momentum diffusivity, and the option to compute poloidal momentum diffusivity. The MMM8.1 model includes a model for ion temperature gradient, trapped electron, kinetic ballooning, peeling, collisionless and collision dominated magnetohydrodynamics modes as well as model for electron temperature gradient modes, and a model for drift resistive inertial ballooning modes. In the derivation of the MMM8.1 module, effects of collisions, fast ion and impurity dilution, non-circular flux surfaces, finite beta, and Shafranov shift are included. The MMM8.1 is used to compute thermal, particle, toroidal, and poloidal angular momentum transports. The fluid approach which underlies the derivation of MMM8.1 is expected to reliably predict, on an energy transport time scale, the evolution of temperature, density, and momentum profiles in plasma discharges for a wide range of plasma conditions.

Upward Pricing Pressure in Two-Sided Markets

NARCIS (Netherlands)

Affeldt, P.; Filistrucchi, L.; Klein, T.J.

2012-01-01

Abstract: Pricing pressure indices have recently been proposed as alternative screening devices for horizontal mergers involving differentiated products. We extend the concept of Upward Pricing Pressure (UPP) proposed by Farrell and Shapiro (2010) to two-sided markets. Examples of such markets are

Nonlinear ion-mixing-mode particle transport in the dissipative trapped electron regime

International Nuclear Information System (INIS)

Ware, A.S.; Terry, P.W.

1993-09-01

The nonlinear particle transport arising from the convection of nonadiabatic electron density by ion temperature gradient driven turbulence is examined for trapped electron collisionality regimes. The renormalized dissipative nonadiabatic trapped electron phase space density response is derived and used to calculate the nonlinear particle flux along with an ansatz for the turbulently broadened frequency spectrum. In the lower temperature end of this regime, trapped electrons are collisional and all components of the quasilinear particle flux are outward (i.e., in the direction of the gradients). Nonlinear effects can alter the phase between the nonadiabatic trapped electron phase space density and the electrostatic potential, producing inward components in the particle flux. Specifically, both turbulent shifting of the peak of the frequency spectrum and nonlinear source terms in the trapped electron response can give rise to inward components. However, in the dissipative regime these terms are small and the trapped electron response remains dominantly laminar. When the trapped electrons are collisionless, there is a temperature threshold above which the electron temperature gradient driven component of the quasilinear particle flux changes sign and becomes inward. For finite amplitude turbulence, however, turbulent broadening of both the electron collisional resonance and the frequency spectrum removes tills threshold., and the temperature gradient driven component remains outward

Derivation of the threshold condition for the ion temperature gradient mode with an inverted density profile from a simple physics picture

Science.gov (United States)

Jhang, Hogun

2018-05-01

We show that the threshold condition for the toroidal ion temperature gradient (ITG) mode with an inverted density profile can be derived from a simple physics argument. The key in this picture is that the density inversion reduces the ion compression due to the ITG mode and the electron drift motion mitigates the poloidal potential build-up. This condition reproduces the same result that has been reported from a linear gyrokinetic calculation [T. S. Hahm and W. M. Tang, Phys. Fluids B 1, 1185 (1989)]. The destabilizing role of trapped electrons in toroidal geometry is easily captured in this picture.

Threatened species richness along a Himalayan elevational gradient: quantifying the influences of human population density, range size, and geometric constraints.

Science.gov (United States)

Paudel, Prakash Kumar; Sipos, Jan; Brodie, Jedediah F

2018-02-07

A crucial step in conserving biodiversity is to identify the distributions of threatened species and the factors associated with species threat status. In the biodiversity hotspot of the Himalaya, very little is known about which locations harbour the highest diversity of threatened species and whether diversity of such species is related to area, mid-domain effects (MDE), range size, or human density. In this study, we assessed the drivers of variation in richness of threatened birds, mammals, reptiles, actinopterygii, and amphibians along an elevational gradient in Nepal Himalaya. Although geometric constraints (MDE), species range size, and human population density were significantly related to threatened species richness, the interaction between range size and human population density was of greater importance. Threatened species richness was positively associated with human population density and negatively associated with range size. In areas with high richness of threatened species, species ranges tend to be small. The preponderance of species at risk of extinction at low elevations in the subtropical biodiversity hotspot could be due to the double impact of smaller range sizes and higher human density.

Ion transition heights from topside electron density profiles

International Nuclear Information System (INIS)

Titheridge, J.E.

1976-01-01

Theoretical electron density profiles are calculated for the topside ionosphere to determine the major factors controlling the profile shape. Only the mean temperature, the vertical temperature gradient and the O + /H + ion transition height are important. Vertical proton fluxes alter the ion transition height but have no other effect on the profile shape. Diffusive equilibrium profiles including only these three effects fit observed profiles, at all latitudes, to within experimental accuracy. Values of plasma temperature, temperature gradient and ion transition height hsub(T) were determined by fitting theoretical models to 60,000 experimental profiles obtained from Alouette 1 ionograms, at latitudes of 75 0 S to 85 0 N near solar minimum. Inside the plasmasphere hsub(T) varies from about 500 km on winter nights to 850 km on summer days. Diurnal variations are caused primarily by the production and loss of O + in the ionosphere. The approximately constant winter night value of hsub(T) is close to the level for chemical equilibrium. In summer hsub(T) is always above the equilibrium level, giving a continual production of protons which travel along lines of force to aid in maintaining the conjugate winter night ionosphere. Outside the plasmasphere hsub(T) is 300 to 600 km above the equilibrium level at all times. This implies a continual near-limiting upwards flux of protons which persists down to latitudes of about 60 0 at night and 50 0 during the day. (author)

Investigating profile stiffness and critical gradients in shaped TCV discharges using local gyrokinetic simulations of turbulent transport

Science.gov (United States)

Merlo, G.; Brunner, S.; Sauter, O.; Camenen, Y.; Görler, T.; Jenko, F.; Marinoni, A.; Told, D.; Villard, L.

2015-05-01

The experimental observation made on the TCV tokamak of a significant confinement improvement in plasmas with negative triangularity (δ TEMs) and electron temperature gradient (ETG) modes are the dominant microinstabilities, with the latter providing a significant contribution to the non-linear electron heat fluxes near the plasma edge. Two series of simulations with different levels of realism are performed, addressing the question of profile stiffness at various radial locations. Retaining finite collisionality, impurities and electromagnetic effects, as well as the physical electron-to-ion mass ratio are all necessary in order to approach the experimental flux measurements. However, flux-tube simulations are unable to fully reproduce the TCV results, pointing towards the need to carry out radially nonlocal (global) simulations, i.e. retaining finite machine size effects, in a future study. Some conclusions about the effect of triangularity can nevertheless be drawn based on the flux-tube results. In particular, the importance of considering the sensitivity to both temperature and density gradient is shown. The flux tube results show an increase of the critical gradients towards the edge, further enhanced when δ < 0, and they also appear to indicate a reduction of profile stiffness towards plasma edge.

Impact of Ficoll density gradient centrifugation on major and trace element concentrations in erythrocytes and blood plasma.

Science.gov (United States)

Lu, Ying; Ahmed, Sultan; Harari, Florencia; Vahter, Marie

2015-01-01

Ficoll density gradient centrifugation is widely used to separate cellular components of human blood. We evaluated the suitability to use erythrocytes and blood plasma obtained from Ficoll centrifugation for assessment of elemental concentrations. We determined 22 elements (from Li to U) in erythrocytes and blood plasma separated by direct or Ficoll density gradient centrifugation, using inductively coupled plasma mass spectrometry. Compared with erythrocytes and blood plasma separated by direct centrifugation, those separated by Ficoll had highly elevated iodine and Ba concentration, due to the contamination from the Ficoll-Paque medium, and about twice as high concentrations of Sr and Mo in erythrocytes. On the other hand, the concentrations of Ca in erythrocytes and plasma were markedly reduced by the Ficoll separation, to some extent also Li, Co, Cu, and U. The reduced concentrations were probably due to EDTA, a chelator present in the Ficoll medium. Arsenic concentrations seemed to be lowered by Ficoll, probably in a species-specific manner. The concentrations of Mg, P, S, K, Fe, Zn, Se, Rb, and Cs were not affected in the erythrocytes, but decreased in plasma. Concentrations of Mn, Cd, and Pb were not affected in erythrocytes, but in plasma affected by EDTA and/or pre-analytical contamination. Ficoll separation changed the concentrations of Li, Ca, Co, Cu, As, Mo, I, Ba, and U in erythrocytes and blood plasma, Sr in erythrocytes, and Mg, P, S, K, Fe, Zn, Se, Rb and Cs in blood plasma, to an extent that will invalidate evaluation of deficiencies or excess intakes. Copyright © 2014 Elsevier GmbH. All rights reserved.

Strength gradient enhances fatigue resistance of steels

Science.gov (United States)

Ma, Zhiwei; Liu, Jiabin; Wang, Gang; Wang, Hongtao; Wei, Yujie; Gao, Huajian

2016-02-01

Steels are heavily used in infrastructure and the transportation industry, and enhancing their fatigue resistance is a major challenge in materials engineering. In this study, by introducing a gradient microstructure into 304 austenitic steel, which is one of the most widely used types of stainless steel, we show that a strength gradient substantially enhances the fatigue life of the material. Pre-notched samples with negative strength gradients in front of the notch’s tip endure many more fatigue cycles than do samples with positive strength gradients during the crack initiation stage, and samples with either type of gradient perform better than do gradient-free samples with the same average yield strength. However, as a crack grows, samples with positive strength gradients exhibit better resistance to fatigue crack propagation than do samples with negative gradients or no gradient. This study demonstrates a simple and promising strategy for using gradient structures to enhance the fatigue resistance of materials and complements related studies of strength and ductility.

Tripolar vortex formation in dense quantum plasma with ion-temperature-gradients

Science.gov (United States)

Qamar, Anisa; Ata-ur-Rahman, Mirza, Arshad M.

2012-05-01

We have derived system of nonlinear equations governing the dynamics of low-frequency electrostatic toroidal ion-temperature-gradient mode for dense quantum magnetoplasma. For some specific profiles of the equilibrium density, temperature, and ion velocity gradients, the nonlinear equations admit a stationary solution in the form of a tripolar vortex. These results are relevant to understand nonlinear structure formation in dense quantum plasmas in the presence of equilibrium ion-temperature and density gradients.

Tripolar vortex formation in dense quantum plasma with ion-temperature-gradients

Energy Technology Data Exchange (ETDEWEB)

Qamar, Anisa; Ata-ur-Rahman [Institute of Physics and Electronics, University of Peshawar, Khyber Pakhtoon Khwa 25000 (Pakistan); National Center for Physics Shahdrah Valley Road, Islamabad 44000 (Pakistan); Mirza, Arshad M. [Theoretical Plasma Physics Group, Physics Department, Quaid-i-Azam University, Islamabad 45320 (Pakistan)

2012-05-15

We have derived system of nonlinear equations governing the dynamics of low-frequency electrostatic toroidal ion-temperature-gradient mode for dense quantum magnetoplasma. For some specific profiles of the equilibrium density, temperature, and ion velocity gradients, the nonlinear equations admit a stationary solution in the form of a tripolar vortex. These results are relevant to understand nonlinear structure formation in dense quantum plasmas in the presence of equilibrium ion-temperature and density gradients.

Tripolar vortex formation in dense quantum plasma with ion-temperature-gradients

International Nuclear Information System (INIS)

Qamar, Anisa; Ata-ur-Rahman; Mirza, Arshad M.

2012-01-01

We have derived system of nonlinear equations governing the dynamics of low-frequency electrostatic toroidal ion-temperature-gradient mode for dense quantum magnetoplasma. For some specific profiles of the equilibrium density, temperature, and ion velocity gradients, the nonlinear equations admit a stationary solution in the form of a tripolar vortex. These results are relevant to understand nonlinear structure formation in dense quantum plasmas in the presence of equilibrium ion-temperature and density gradients.

Effect of density control and impurity transport on internal transport barrier formation in tokamak plasma

International Nuclear Information System (INIS)

Yamakami, Tomoyuki; Fujita, Takaaki; Arimoto, Hideki; Yamazaki, Kozo

2014-01-01

In future fusion reactors, density control, such as fueling by pellet injection, is an effective method to control the formation of the internal transport barrier (ITB) in reversed magnetic shear plasma, which can improve plasma performance. On the other hand, an operation with ITB can cause accumulation of impurities inside the core ITB region. We studied the relation between pellet injection and ITB formation and the effect of impurity transport on the core of ITB for tokamak plasmas by using the toroidal transport analysis linkage. For ITB formation, we showed that the pellet has to be injected beyond the position where the safety factor q takes the minimum value. We confirmed that the accumulation of impurities causes the attenuation of ITB owing to radiation loss inside the ITB region. Moreover, in terms of the divertor heat flux reduction by impurity gas, the line radiation loss is high for high-Z noble gas impurities, such as Kr, whereas factor Q decreases slightly. (author)

Analysis of Rotation and Transport Data in C-Mod ITB Plasmas

Science.gov (United States)

Fiore, C. L.; Rice, J. E.; Reinke, M. L.; Podpaly, Y.; Bespamyatnov, I. O.; Rowan, W. L.

2009-11-01

Internal transport barriers (ITBs) spontaneously form near the half radius of Alcator C-Mod plasmas when the EDA H-mode is sustained for several energy confinement times in either off-axis ICRF heated discharges or in purely ohmic heated plasmas. These plasmas exhibit strongly peaked density and pressure profiles, static or peaking temperature profiles, peaking impurity density profiles, and thermal transport coefficients that approach neoclassical values in the core. It has long been observed that the intrinsic central plasma rotation that is strongly co-current following the H-mode transition slows and often reverses as the density peaks as the ITB forms. Recent spatial measurements demonstrate that the rotation profile develops a well in the core region that decreases continuously as central density rises while the value outside of the core remains strongly co-current. This results in the formation of a steep potential gradient/strong electric field at the location of the foot of the ITB density profile. The resulting E X B shearing rate is also quite significant at the foot. These analyses and the implications for plasma transport and stability will be presented.

Enviromental Effects on Internal Color Gradients of Early-Type Galaxies

Science.gov (United States)

La Barbera, F.; de Carvalho, R. R.; Gal, R. R.; Busarello, G.; Haines, C. P.; Mercurio, A.; Merluzzi, P.; Capaccioli, M.; Djorgovski, S. G.

2007-05-01

One of the most debated issues of observational and theoretical cosmology is that of how the environment affects the formation and evolution of galaxies. To gain new insight into this subject, we have derived surface photometry for a sample of 3,000 early-type galaxies belonging to 163 clusters with different richness, spanning a redshift range of 0.05 to 0.25. This large data-set is used to analyze how the color distribution inside galaxies depends on several parameters, such as cluster richness, local galaxy density, galaxy luminosity and redshift. We find that the internal color profile of galaxies strongly depends on the environment where galaxies reside. Galaxies in poor and rich clusters are found to follow two distinct trends in the color gradient vs. redshift diagram, with color gradients beeing less steep in rich rather than in poor clusters. No dependence of color gradients on galaxy luminosity is detected both for poor and rich clusters. We find that color gradients strongly depend on local galaxy density, with more shallow gradients in high density regions. Interestingly, this result holds only for low richness clusters, with color gradients of galaxies in rich clusters showing no dependence on local galaxy density. Our results support a reasonable picture whereby young early-type galaxies form in a dissipative collapse process, and then undergo increased (either major or minor) merging activity in richer rather than in poor clusters.

On the diffusive nature of W7-AS transport

International Nuclear Information System (INIS)

Stroth, U.; Giannone, L.; Erckmann, V.; Geist, T.; Hartfuss, H.J.; Jaenicke, R.; Kuehner, G.; Ringler, H.; Sardei, F.

1993-01-01

Particle and energy transport in W7-AS have many aspects which are in qualitative agreement with diffusive transport mechanisms. Unlike in tokamaks, the density profiles are flat in the source-free region and for the electron temperature no profile resilience is observed. A strong dependence of transport on the temperature gradient could be ruled out since agreement between the transport coefficients from steady state and perturbative studies has been observed both, in absolute value and parameter dependences. Furthermore, W7-AS transport was found to be compatible with a gyro-Bohm-like and, hence, local transport model. Similar to tokamaks, however, there are problems in relating the local transport coefficients to local plasma parameters. Especially the degradation of confinement with heating power cannot easily be connected to a local quantity. This difficulty is the subject of this paper. (orig.)

Investigation of the density turbulence in ohmic ASDEX plasmas

International Nuclear Information System (INIS)

Dodel, G.; Holtzhauer, E.

1989-01-01

A 119 μm homodyne laser scattering experiment is used on ASDEX to investigate wavenumber and frequency of the density fluctuations occuring in the different operational conditions of the machine. The changes of the density turbulence caused by additional heating are of primary interest with regard to a possible correlation to anomalous transport. Therefore, in the current experiment particular emphasis is placed on these investigations. On the other hand it is the ohmic phase which constitutes the least complicated physical situation in a tokamak and is therefore best suited to reveal the basic physical nature of the density turbulence. In the following we present a summary of our findings in the ohmic phase and make an attempt to compare these findings with what would be expected from the simplest model of density-gradient-driven driftwave turbulence saturated at the mixing-length level. (author) 3 refs., 4 figs

Investigation of the density turbulence in ohmic ASDEX plasmas

Energy Technology Data Exchange (ETDEWEB)

Dodel, G; Holtzhauer, E [Stuttgart Univ. (Germany, F.R.). Inst. fuer Plasmaforschung; Giannone, L.; Niedermeyer, H [Max-Planck-Institut fuer Plasmaphysik, Garching (Germany, F.R.)

1989-01-01

A 119 {mu}m homodyne laser scattering experiment is used on ASDEX to investigate wavenumber and frequency of the density fluctuations occuring in the different operational conditions of the machine. The changes of the density turbulence caused by additional heating are of primary interest with regard to a possible correlation to anomalous transport. Therefore, in the current experiment particular emphasis is placed on these investigations. On the other hand it is the ohmic phase which constitutes the least complicated physical situation in a tokamak and is therefore best suited to reveal the basic physical nature of the density turbulence. In the following we present a summary of our findings in the ohmic phase and make an attempt to compare these findings with what would be expected from the simplest model of density-gradient-driven driftwave turbulence saturated at the mixing-length level. (author) 3 refs., 4 figs.

Upward pricing pressure in two-sided markets

NARCIS (Netherlands)

Affeldt, P.; Filistrucchi, L.; Klein, T.J.

2013-01-01

Measuring upward pricing pressure (UPP) has recently been proposed by Farrell and Shapiro (2010) as an alternative screening device for horizontal mergers. We extend the concept of UPP to two-sided markets. Examples of such markets are the newspaper market, where the demand for advertising is

A Study of Upward Influence in Organizations.

Science.gov (United States)

Schilit, Warren K.; Locke, Edwin A.

1982-01-01

Researchers interviewed 83 subordinate employees and 70 supervisory employees to investigate the ways subordinates try to influence their supervisors. Supervisors and subordinates reported similar agents and methods of influence, causes of success, and outcomes of attempts at upward influence, but different causes of failure. (Author/RW)

Compressibility and rotation effects on transport suppression in magnetohydrodynamic turbulence

International Nuclear Information System (INIS)

Yoshizawa, A.

1996-01-01

Compressibility and rotation effects on turbulent transports in magnetohydrodynamic (MHD) flows under arbitrary mean field are investigated using a Markovianized two-scale statistical approach. Some new aspects of MHD turbulence are pointed out in close relation to plasma compressibility. Special attention is paid to the turbulent electromotive force, which plays a central role in the generation of magnetic and velocity fluctuations. In addition to plasma rotation, the interaction between compressibility and magnetic fields is shown to bring a few factors suppressing MHD fluctuations and, eventually, density and temperature transports, even in the presence of steep mean density and temperature gradients. This finding is discussed in the context of the turbulence-suppression mechanism in the tokamak close-quote s high-confinement modes. copyright 1996 American Institute of Physics

Distribution, behavior, and transport of inorganic and methylmercury in a high gradient stream

International Nuclear Information System (INIS)

Flanders, J.R.; Turner, R.R.; Morrison, T.; Jensen, R.; Pizzuto, J.; Skalak, K.; Stahl, R.

2010-01-01

Research highlights: → Sources of inorganic mercury widespread in high-gradient fluvial system decades after mercury use ceased in watershed. → Soils release more inorganic mercury than sediment, primarily complexed by colloids. → Methylmercury is produced in wide range of habitats despite the high gradient and coarse-grained nature of river. → Methylmercury under complex physical and chemical controls, including temperature, bioavailable mercury, and substrates (carbon and electron acceptors). - Abstract: Concentrations of Hg remain elevated in physical and biological media of the South River (Virginia, USA), despite the cessation of the industrial use of Hg in its watershed nearly six decades ago, and physical characteristics that would not seem to favor Hg(II)-methylation. A 3-a study of inorganic Hg (IHg) and methylmercury (MeHg) was conducted in physical media (soil, sediment, surface water, porewater and soil/sediment extracts) to identify non-point sources, transport mechanisms, and potential controls on Hg(II)-methylation. Data collected from surface water and sediment indicate that the majority of the non-point sources of IHg to the South River are within the first 14 km downstream from the historic point source. Partitioning data indicate that particle bound IHg is introduced in this reach, releasing dissolved and colloidal bound IHg, which is transported downstream. Extraction experiments revealed that floodplain soils released a higher fraction of their IHg content in aqueous extractions than fine-grained sediment (FGS). Based on ultrafiltration [<5000 nominal molecular weight cutoff (NMWC)] the majority of soil IHg released was colloidal in nature, providing evidence for the continued evolution of IHg for Hg(II)-methylation from soil. Strong seasonal patterns in MeHg concentrations were observed in surface water and sediment. The highest concentrations of MeHg in surface water were observed at moderate temperatures, suggesting that other

Distribution, behavior, and transport of inorganic and methylmercury in a high gradient stream

Energy Technology Data Exchange (ETDEWEB)

Flanders, J.R., E-mail: john_flanders@urscorp.com [URS Corporation, 335 Commerce Drive, Suite 300, Fort Washington, PA 19034 (United States); Turner, R.R. [RTGeosciences Inc., PO Box 421, Squamish, BC (Canada); Morrison, T. [URS Corporation, 335 Commerce Drive, Suite 300, Fort Washington, PA 19034 (United States); Jensen, R. [Unique Environmental Services, 5406 Crestline Rd., Wilmington, DE 19808 (United States); Pizzuto, J. [University of Delaware, Department of Geology, 101D Penny Hall, Newark, DE 19716 (United States); Skalak, K. [US Geological Survey, 430 National Center, Reston, VA 20192 (United States); Stahl, R. [DuPont Corporate Remediation Group, 1447 Lancaster Pike, Wilmington, DE (United States)

2010-11-15

Research highlights: {yields} Sources of inorganic mercury widespread in high-gradient fluvial system decades after mercury use ceased in watershed. {yields} Soils release more inorganic mercury than sediment, primarily complexed by colloids. {yields} Methylmercury is produced in wide range of habitats despite the high gradient and coarse-grained nature of river. {yields} Methylmercury under complex physical and chemical controls, including temperature, bioavailable mercury, and substrates (carbon and electron acceptors). - Abstract: Concentrations of Hg remain elevated in physical and biological media of the South River (Virginia, USA), despite the cessation of the industrial use of Hg in its watershed nearly six decades ago, and physical characteristics that would not seem to favor Hg(II)-methylation. A 3-a study of inorganic Hg (IHg) and methylmercury (MeHg) was conducted in physical media (soil, sediment, surface water, porewater and soil/sediment extracts) to identify non-point sources, transport mechanisms, and potential controls on Hg(II)-methylation. Data collected from surface water and sediment indicate that the majority of the non-point sources of IHg to the South River are within the first 14 km downstream from the historic point source. Partitioning data indicate that particle bound IHg is introduced in this reach, releasing dissolved and colloidal bound IHg, which is transported downstream. Extraction experiments revealed that floodplain soils released a higher fraction of their IHg content in aqueous extractions than fine-grained sediment (FGS). Based on ultrafiltration [<5000 nominal molecular weight cutoff (NMWC)] the majority of soil IHg released was colloidal in nature, providing evidence for the continued evolution of IHg for Hg(II)-methylation from soil. Strong seasonal patterns in MeHg concentrations were observed in surface water and sediment. The highest concentrations of MeHg in surface water were observed at moderate temperatures

Transient particle transport studies at the W7-AS stellarator

International Nuclear Information System (INIS)

Koponen, J.

2000-01-01

One of the crucial problems in fusion research is the understanding of the transport of particles and heat in plasmas relevant for energy production. Extensive experimental transport studies have unraveled many details of heat transport in tokamaks and stellarators. However, due to larger experimental difficulties, the properties of particle transport have remained much less known. In particular, very few particle transport studies have been carried out in stellarators. This thesis summarises the transient particle transport experiments carried out at the Wendelstein 7-Advanced Stellarator (W7-AS). The main diagnostics tool was a 10-channel microwave interferometer. A technique for reconstructing the electron density profiles from the multichannel interferometer data was developed and implemented. The interferometer and the reconstruction software provide high quality electron density measurements with high temporal and sufficient spatial resolution. The density reconstruction is based on regularization methods studied during the development work. An extensive program of transient particle transport studies was carried out with the gas modulation method. The experiments resulted in a scaling expression for the diffusion coefficient. Transient inward convection was found in the edge plasma. The role of convection is minor in the core plasma, except at higher heating power, when an outward directed convective flux is observed. Radially peaked density profiles were found in discharges free of significant central density sources. Such density profiles are usually observed in tokamaks, but never before in W7-AS. Existence of an inward pinch is confirmed with two independent transient transport analysis methods. The density peaking is possible if the plasma is heated with extreme off-axis Electron Cyclotron Heating (ECH), when the temperature gradient vanishes in the core plasma, and if the gas puffing level is relatively low. The transport of plasma particles and heat

Modeling of the Dorsal Gradient across Species Reveals Interaction between Embryo Morphology and Toll Signaling Pathway during Evolution

Science.gov (United States)

Koslen, Hannah R.; Chiel, Hillel J.; Mizutani, Claudia Mieko

2014-01-01

Morphogenetic gradients are essential to allocate cell fates in embryos of varying sizes within and across closely related species. We previously showed that the maternal NF-κB/Dorsal (Dl) gradient has acquired different shapes in Drosophila species, which result in unequally scaled germ layers along the dorso-ventral axis and the repositioning of the neuroectodermal borders. Here we combined experimentation and mathematical modeling to investigate which factors might have contributed to the fast evolutionary changes of this gradient. To this end, we modified a previously developed model that employs differential equations of the main biochemical interactions of the Toll (Tl) signaling pathway, which regulates Dl nuclear transport. The original model simulations fit well the D. melanogaster wild type, but not mutant conditions. To broaden the applicability of this model and probe evolutionary changes in gradient distributions, we adjusted a set of 19 independent parameters to reproduce three quantified experimental conditions (i.e. Dl levels lowered, nuclear size and density increased or decreased). We next searched for the most relevant parameters that reproduce the species-specific Dl gradients. We show that adjusting parameters relative to morphological traits (i.e. embryo diameter, nuclear size and density) alone is not sufficient to reproduce the species Dl gradients. Since components of the Tl pathway simulated by the model are fast-evolving, we next asked which parameters related to Tl would most effectively reproduce these gradients and identified a particular subset. A sensitivity analysis reveals the existence of nonlinear interactions between the two fast-evolving traits tested above, namely the embryonic morphological changes and Tl pathway components. Our modeling further suggests that distinct Dl gradient shapes observed in closely related melanogaster sub-group lineages may be caused by similar sequence modifications in Tl pathway components, which

Liquid velocity in upward and downward air-water flows

International Nuclear Information System (INIS)

Sun Xiaodong; Paranjape, Sidharth; Kim, Seungjin; Ozar, Basar; Ishii, Mamoru

2004-01-01

Local characteristics of the liquid phase in upward and downward air-water two-phase flows were experimentally investigated in a 50.8-mm inner-diameter round pipe. An integral laser Doppler anemometry (LDA) system was used to measure the axial liquid velocity and its fluctuations. No effect of the flow direction on the liquid velocity radial profile was observed in single-phase liquid benchmark experiments. Local multi-sensor conductivity probes were used to measure the radial profiles of the bubble velocity and the void fraction. The measurement results in the upward and downward two-phase flows are compared and discussed. The results in the downward flow demonstrated that the presence of the bubbles tended to flatten the liquid velocity radial profile, and the maximum liquid velocity could occur off the pipe centerline, in particular at relatively low flow rates. However, the maximum liquid velocity always occurred at the pipe center in the upward flow. Also, noticeable turbulence enhancement due to the bubbles in the two-phase flows was observed in the current experimental flow conditions. Furthermore, the distribution parameter and the void-weighted area-averaged drift velocity were obtained based on the definitions

Upward lightning attachment analysis on wind turbines and correlated current parameters

DEFF Research Database (Denmark)

Vogel, Stephan; Ishii, M.; Saito, M.

2017-01-01

This work provides insight in the attachment characteristics of upward initiated lightning discharges to wind turbines and their possible consequences for the lightning protection of wind turbine blades. All discharges were recorded at the Japanese coast of the Sea of Japan which is known...... for intense upward lightning activity. 172 video recordings of lightning discharges on rotating wind turbines are analysed and attachment angle, detachment angle, and the resulting angular displacement were determined. A classification between self-initiated and other-triggered upward lightning events...... is performed by means of video analysis. The results reveal that the majority of discharges are initiated on vertical blades; however, also attachments to horizontal blades are reported. Horizontal attachment (or a slightly inclined blade state) is often related with a triggered lightning event prior...

Ion temperature gradient instability

International Nuclear Information System (INIS)

1989-01-01

Anomalous ion thermal conductivity remains an open physics issue for the present generation of high temperature Tokamaks. It is generally believed to be due to Ion Temperature Gradient Instability (η i mode). However, it has been difficult, if not impossible to identify this instability and study the anomalous transport due to it, directly. Therefore the production and identification of the mode is pursued in the simpler and experimentally convenient configuration of the Columbia Linear Machine (CLM). CLM is a steady state machine which already has all the appropriate parameters, except η i . This parameter is being increased to the appropriate value of the order of 1 by 'feathering' a tungsten screen located between the plasma source and the experimental cell to flatten the density profile and appropriate redesign of heating antennas to steepen the ion temperature profile. Once the instability is produced and identified, a thorough study of the characteristics of the mode can be done via a wide range of variation of all the critical parameters: η i , parallel wavelength, etc

Dependence of mitochondrial coenzyme A uptake on the membrane electrical gradient

International Nuclear Information System (INIS)

Tahiliani, A.G.

1989-01-01

Coenzyme A (CoA) transport was studied in isolated rat heart mitochondria. Uptake of CoA was assayed by determining [3H]CoA associated with mitochondria under various conditions. Various oxidizable substrates including alpha-ketoglutarate, succinate, or malate stimulated CoA uptake. The membrane proton (delta pH) and electrical (delta psi) gradients, which dissipated with time in the absence of substrate, were maintained at their initial levels throughout the incubation in the presence of substrate. Addition of phosphate caused a concentration-dependent decrease of both delta pH and CoA uptake. Nigericin also dissipated the proton gradient and prevented CoA uptake. Valinomycin also prevented CoA uptake into mitochondria. Although the proton gradient was unaffected, the electrical gradient was completely abolished in the presence of valinomycin. Addition of 5 mM phosphate 10 min after the start of incubation prevented further uptake of CoA into mitochondria. A rapid dissipation of the proton gradient upon addition of phosphate was observed. Addition of nigericin or valinomycin 10 min after the start of incubation also resulted in no further uptake of CoA into with mitochondria; valinomycin caused an apparent efflux of CoA from mitochondria. Uptake was found to be sensitive to external pH displaying a pH optimum at pHext 8.0. Although nigericin significantly inhibited CoA uptake over the pHext range of 6.75-8, maximal transport was observed around pHext 8.0-8.25. Valinomycin, on the other hand, abolished transport over the entire pH range. The results suggest that mitochondrial CoA transport is determined by the membrane electrical gradient. The apparent dependence of CoA uptake on an intact membrane pH gradient is probably the result of modulation of CoA transport by matrix pH

High-performance ionic diode membrane for salinity gradient power generation.

Science.gov (United States)

Gao, Jun; Guo, Wei; Feng, Dan; Wang, Huanting; Zhao, Dongyuan; Jiang, Lei

2014-09-03

Salinity difference between seawater and river water is a sustainable energy resource that catches eyes of the public and the investors in the background of energy crisis. To capture this energy, interdisciplinary efforts from chemistry, materials science, environmental science, and nanotechnology have been made to create efficient and economically viable energy conversion methods and materials. Beyond conventional membrane-based processes, technological breakthroughs in harvesting salinity gradient power from natural waters are expected to emerge from the novel fluidic transport phenomena on the nanoscale. A major challenge toward real-world applications is to extrapolate existing single-channel devices to macroscopic materials. Here, we report a membrane-scale nanofluidic device with asymmetric structure, chemical composition, and surface charge polarity, termed ionic diode membrane (IDM), for harvesting electric power from salinity gradient. The IDM comprises heterojunctions between mesoporous carbon (pore size ∼7 nm, negatively charged) and macroporous alumina (pore size ∼80 nm, positively charged). The meso-/macroporous membrane rectifies the ionic current with distinctly high ratio of ca. 450 and keeps on rectifying in high-concentration electrolytes, even in saturated solution. The selective and rectified ion transport furthermore sheds light on salinity-gradient power generation. By mixing artificial seawater and river water through the IDM, substantially high power density of up to 3.46 W/m(2) is discovered, which largely outperforms some commercial ion-exchange membranes. A theoretical model based on coupled Poisson and Nernst-Planck equations is established to quantitatively explain the experimental observations and get insights into the underlying mechanism. The macroscopic and asymmetric nanofluidic structure anticipates wide potentials for sustainable power generation, water purification, and desalination.

Gradient networks on uncorrelated random scale-free networks

International Nuclear Information System (INIS)

Pan Guijun; Yan Xiaoqing; Huang Zhongbing; Ma Weichuan

2011-01-01

Uncorrelated random scale-free (URSF) networks are useful null models for checking the effects of scale-free topology on network-based dynamical processes. Here, we present a comparative study of the jamming level of gradient networks based on URSF networks and Erdos-Renyi (ER) random networks. We find that the URSF networks are less congested than ER random networks for the average degree (k)>k c (k c ∼ 2 denotes a critical connectivity). In addition, by investigating the topological properties of the two kinds of gradient networks, we discuss the relations between the topological structure and the transport efficiency of the gradient networks. These findings show that the uncorrelated scale-free structure might allow more efficient transport than the random structure.

Changes in electrical transport and density of states of phase change materials upon resistance drift

International Nuclear Information System (INIS)

Krebs, Daniel; Bachmann, Tobias; Jonnalagadda, Prasad; Dellmann, Laurent; Raoux, Simone

2014-01-01

Phase-change memory technology has become more mature in recent years. But some fundamental problems linked to the electrical transport properties in the amorphous phase of phase-change materials still need to be solved. The increase of resistance over time, called resistance drift, for example, poses a major challenge for the implementation of multilevel storage, which will eventually be necessary to remain competitive in terms of high storage densities. To link structural properties with electrical transport, a broader knowledge of (i) changes in the density of states (DoS) upon structural relaxation and (ii) the influence of defects on electrical transport is required. In this paper, we present temperature-dependent conductivity and photo-conductivity measurements on the archetype phase change material GeTe. It is shown that trap-limited band transport at high temperatures (above 165 K) and variable range hopping at low temperatures are the predominating transport mechanism. Based on measurements of the temperature dependence of the optical band gap, modulated photo-conductivity and photo-thermal deflection spectroscopy, a DoS model for GeTe was proposed. Using this DoS, the temperature dependence of conductivity and photo-conductivity has been simulated. Our work shows how changes in the DoS (band gap and defect distributions) will affect the electrical transport before and after temperature-accelerated drift. The decrease in conductivity upon annealing can be explained entirely by an increase of the band gap by about 12%. However, low-temperature photo-conductivity measurements revealed that a change in the defect density may also play a role

Reduced density gradient as a novel approach for estimating QSAR descriptors, and its application to 1, 4-dihydropyridine derivatives with potential antihypertensive effects.

Science.gov (United States)

Jardínez, Christiaan; Vela, Alberto; Cruz-Borbolla, Julián; Alvarez-Mendez, Rodrigo J; Alvarado-Rodríguez, José G

2016-12-01

The relationship between the chemical structure and biological activity (log IC 50 ) of 40 derivatives of 1,4-dihydropyridines (DHPs) was studied using density functional theory (DFT) and multiple linear regression analysis methods. With the aim of improving the quantitative structure-activity relationship (QSAR) model, the reduced density gradient s( r) of the optimized equilibrium geometries was used as a descriptor to include weak non-covalent interactions. The QSAR model highlights the correlation between the log IC 50 with highest molecular orbital energy (E HOMO ), molecular volume (V), partition coefficient (log P), non-covalent interactions NCI(H4-G) and the dual descriptor [Δf(r)]. The model yielded values of R 2 =79.57 and Q 2 =69.67 that were validated with the next four internal analytical validations DK=0.076, DQ=-0.006, R P =0.056, and R N =0.000, and the external validation Q 2 boot =64.26. The QSAR model found can be used to estimate biological activity with high reliability in new compounds based on a DHP series. Graphical abstract The good correlation between the log IC 50 with the NCI (H4-G) estimated by the reduced density gradient approach of the DHP derivatives.

BMP4 density gradient in disk-shaped confinement

Science.gov (United States)

Bozorgui, Behnaz; Teimouri, Hamid; Kolomeisky, Anatoly B.

We present a quantitative model that explains the scaling of BMP4 gradients during gastrulation and the recent experimental observation that geometric confinement of human embryonic stem cells is sufficient to recapitulate much of germ layer patterning. Based on a assumption that BMP4 diffusion rate is much smaller than the diffusion rate of it's inhibitor molecules, our results confirm that the length-scale which defines germ layer territories does not depend on system size.

EFFECTIVENESS OF DOUBLE WASH SWIM-UP VERSUS DOUBLE DENSITY GRADIENT SWIM-UP TECHNIQUE OF SPERM PREPARATION IN IN VITRO FERTILISATION

OpenAIRE

Srinivas Sangisapu; Sandeep Karunakaran; Ashok Kumar Pillai

2017-01-01

BACKGROUND Recovery of optimum number of good quality of spermatozoa is an important component of In Vitro Fertilisation (IVF). This is achieved by sperm preparation methods involving separation and recovery of capacitated sperms. Double Wash Swim-up (DWSU) and Double Density Gradient Swim-up (DDGSU) are two most accepted methods. Cochrane systematic review (2007) finds no clear benefit of one method over the other in Intrauterine Insemination (IUI). Systematic review on effective...

Influence of a thermal gradient on water-rock interactions and mass transport in geologic media (marine pelagic clay)

International Nuclear Information System (INIS)

Seyfried, W.E. Jr.

1985-01-01

A brief outline of the role of thermodiffusional processes in mass transport and sediment alteration for a sediment/seawater system that is subjected to a thermal gradient and maximum temperature and pressure condition, such as in a subseabed repository is presented. The author underscores the need to investigate the effect of basic physical and chemical parameters on Soret coefficients for various electrolyte fluids. Such experiments will require the design and development of unique hydrothermal apparatus

Improving the theoretical foundations of the multi-mode transport model

International Nuclear Information System (INIS)

Bateman, G.; Kritz, A.H.; Redd, A.J.; Erba, M.; Rewoldt, G.; Weiland, J.; Strand, P.; Kinsey, J.E.; Scott, B.

1999-01-01

A new version of the Multi-Mode transport model, designated MMM98, is being developed with improved theoretical foundations, in an ongoing effort to predict the temperature and density profiles in tokamaks. For transport near the edge of the plasma, MMM98 uses a new model based on 3-D nonlinear simulations of drift Alfven mode turbulence. Flow shear stabilization effects have been added to the Weiland model for Ion Temperature Gradient and Trapped Electron Modes, which usually dominates in most of the plasma core. For transport near the magnetic axis at high beta, a new kinetic ballooning mode model has been constructed based on FULL stability code computations. (author)

Improving the theoretical foundations of the multi-mode transport model

International Nuclear Information System (INIS)

Bateman, G.; Kritz, A.H.; Redd, A.J.; Erba, M.; Rewoldt, G.; Weiland, J.; Strand, P.; Kinsey, J.E.; Scott, B.

2001-01-01

A new version of the Multi-Mode transport model, designated MMM98, is being developed with improved theoretical foundations, in an ongoing effort to predict the temperature and density profiles in tokamaks. For transport near the edge of the plasma, MMM98 uses a new model based on 3-D nonlinear simulations of drift Alfven mode turbulence. Flow shear stabilization effects have been added to the Weiland model for Ion Temperature Gradient and Trapped Electron Modes, which usually dominates in most of the plasma core. For transport near the magnetic axis at high beta, a new kinetic ballooning mode model has been constructed based on FULL stability code computations. (author)

Spatially Different Tissue-Scale Diffusivity Shapes ANGUSTIFOLIA3 Gradient in Growing Leaves.

Science.gov (United States)

Kawade, Kensuke; Tanimoto, Hirokazu; Horiguchi, Gorou; Tsukaya, Hirokazu

2017-09-05

The spatial gradient of signaling molecules is pivotal for establishing developmental patterns of multicellular organisms. It has long been proposed that these gradients could arise from the pure diffusion process of signaling molecules between cells, but whether this simplest mechanism establishes the formation of the tissue-scale gradient remains unclear. Plasmodesmata are unique channel structures in plants that connect neighboring cells for molecular transport. In this study, we measured cellular- and tissue-scale kinetics of molecular transport through plasmodesmata in Arabidopsis thaliana developing leaf primordia by fluorescence recovery assays. These trans-scale measurements revealed biophysical properties of diffusive molecular transport through plasmodesmata and revealed that the tissue-scale diffusivity, but not the cellular-scale diffusivity, is spatially different along the leaf proximal-to-distal axis. We found that the gradient in cell size along the developmental axis underlies this spatially different tissue-scale diffusivity. We then asked how this diffusion-based framework functions in establishing a signaling gradient of endogenous molecules. ANGUSTIFOLIA3 (AN3) is a transcriptional co-activator, and as we have shown here, it forms a long-range signaling gradient along the leaf proximal-to-distal axis to determine a cell-proliferation domain. By genetically engineering AN3 mobility, we assessed each contribution of cell-to-cell movement and tissue growth to the distribution of the AN3 gradient. We constructed a diffusion-based theoretical model using these quantitative data to analyze the AN3 gradient formation and demonstrated that it could be achieved solely by the diffusive molecular transport in a growing tissue. Our results indicate that the spatially different tissue-scale diffusivity is a core mechanism for AN3 gradient formation. This provides evidence that the pure diffusion process establishes the formation of the long-range signaling

Gyrokinetic Studies of Turbulence in Steep Gradient Region: Role of Turbulence Spreading and E x B Shear

Energy Technology Data Exchange (ETDEWEB)

T.S. Hahm; Z. Lin; P.H. Diamond; G. Rewoldt; W.X. Wang; S. Ethier; O. Gurcan; W.W. Lee; W.M. Tang

2004-12-21

An integrated program of gyrokinetic particle simulation and theory has been developed to investigate several outstanding issues in both turbulence and neoclassical physics. Gyrokinetic particle simulations of toroidal ion temperature gradient (ITG) turbulence spreading using the GTC code and its related dynamical model have been extended to the case with radially increasing ion temperature gradient, to study the inward spreading of edge turbulence toward the core. Due to turbulence spreading from the edge, the turbulence intensity in the core region is significantly enhanced over the value obtained from simulations of the core region only. Even when the core gradient is within the Dimits shift regime (i.e., self-generated zonal flows reduce the transport to a negligible value), a significant level of turbulence and transport is observed in the core due to spreading from the edge. The scaling of the turbulent front propagation speed is closer to the prediction from our nonlinear diffusion model than one based on linear toroidal coupling. A calculation of ion poloidal rotation in the presence of sharp density and toroidal angular rotation frequency gradients from the GTC-Neo particle simulation code shows that the results are significantly different from the conventional neoclassical theory predictions. An energy conserving set of a fully electromagnetic nonlinear gyrokinetic Vlasov equation and Maxwell's equations, which is applicable to edge turbulence, is being derived via the phase-space action variational Lie perturbation method. Our generalized ordering takes the ion poloidal gyroradius to be on the order of the radial electric field gradient length.

Gyrokinetic studies of turbulence in steep gradient region: Role of turbulence spreading and E x B shear

International Nuclear Information System (INIS)

Hahm, T.S.; Lin, Z.; Diamond, P.H.; Gurcan, O.; Rewoldt, G.; Wang, W.X.; Ethier, S.; Lee, W.W.; Lewandowski, J.L.V.; Tang, W.M.

2005-01-01

An integrated program of gyrokinetic particle simulation and theory has been developed to investigate several outstanding issues in both turbulence and neoclassical physics. Gyrokinetic particle simulations of toroidal ion temperature gradient (ITG) turbulence spreading using the GTC code and its related dynamical model have been extended to the case with radially increasing ion temperature gradient, to study the inward spreading of edge turbulence toward the core. Due to turbulence spreading from the edge, the turbulence intensity in the core region is significantly enhanced over the value obtained from simulations of the core region only. Even when the core gradient is within the Dimits shift regime (i.e., self-generated zonal flows reduce the transport to a negligible value), a significant level of turbulence and transport is observed in the core due to spreading from the edge. The scaling of the turbulent front propagation speed is closer to the prediction from our nonlinear diffusion model than one based on linear toroidal coupling. A calculation of ion poloidal rotation in the presence of sharp density and toroidal angular rotation frequency gradients from the GTC-Neo particle simulation code shows that the results are significantly different from the conventional neoclassical theory predictions. An energy conserving set of a fully electromagnetic nonlinear gyrokinetic Vlasov equation and Maxwell's equations, which is applicable to edge turbulence, is being derived via the phase-space action variational Lie perturbation method. Our generalized ordering takes the ion poloidal gyroradius to be on the order of the radial electric field gradient length. (author)

Simulation of internal transport barriers by means of the canonical profile transport model

International Nuclear Information System (INIS)

Dnestrovskij, Yu. N.; Cherkasov, S. V.; Dnestrovskij, A. Yu.; Lysenko, S. E.; Walsh, M. J.

2006-01-01

Models with critical gradients are widely used to describe energy balance in L-mode discharges. The so-called first critical gradient can be found from the canonical temperature profile. Here, it is suggested that discharge regimes with transport barriers can be described based on the idea of the second critical gradient. If, in a certain plasma region, the pressure gradient exceeds the second critical gradient, then the plasma bifurcates into a new state and a transport barrier forms in this region. This idea was implemented in a modified canonical profile transport model that makes it possible to describe the energy and particle balance in tokamak plasmas with arbitrary cross sections and aspect ratios. The magnitude of the second critical gradient was chosen by comparing the results calculated for several tokamak discharges with the experimental data. It is found that the second critical gradient is related to the magnetic shear s. The criterion of the transport barrier formation has the form (a 2 /r)d/drln(p/p c ) > z 0 (r), where r is the radial coordinate, a is the plasma minor radius, p is the plasma pressure, p c is the canonical pressure profile, and the dimensionless function z O (r) = C O + C 1 s (with C 0i ∼1, C 0e ∼3, and C 1i,e ∼2) describes the difference between the first and second critical gradients. Simulations show that this criterion is close to that obtained experimentally in JET. The model constructed here is used to simulate internal transport barriers in the JET, TFTR, DIII-D, and MAST tokamaks. The possible dependence of the second critical gradient on the plasma parameters is discussed

Electron density interferometry measurement in laser-matter interaction

International Nuclear Information System (INIS)

Popovics-Chenais, C.

1981-05-01

This work is concerned with the laser-interferometry measurement of the electronic density in the corona and the conduction zone external part. Particularly, it is aimed at showing up density gradients and at their space-time localization. The first chapter recalls the density profile influence on the absorption principal mechanisms and the laser energy transport. In chapter two, the numerical and analytical hydrodynamic models describing the density profile are analysed. The influence on the density profile of the ponderomotive force associated to high oscillating electric fields is studied, together with the limited thermal conduction and suprathermal electron population. The mechanism action, in our measurement conditions, is numerically simulated. Calculations are made with experimental parameters. The measurement interaction conditions, together with the diagnostic method by high resolution laser interferometry are detailed. The results are analysed with the help of numerical simulation which is the experiment modeling. An overview of the mechanisms shown up by interferometric measurements and their correlation with other diagnostics is the conclusion of this work [fr

Mapping axonal density and average diameter using non-monotonic time-dependent gradient-echo MRI

DEFF Research Database (Denmark)

Nunes, Daniel; Cruz, Tomás L; Jespersen, Sune N

2017-01-01

available in the clinic, or extremely long acquisition schemes to extract information from parameter-intensive models. In this study, we suggest that simple and time-efficient multi-gradient-echo (MGE) MRI can be used to extract the axon density from susceptibility-driven non-monotonic decay in the time...... the quantitative results are compared against ground-truth histology, they seem to reflect the axonal fraction (though with a bias, as evident from Bland-Altman analysis). As well, the extra-axonal fraction can be estimated. The results suggest that our model is oversimplified, yet at the same time evidencing......-dependent signal. We show, both theoretically and with simulations, that a non-monotonic signal decay will occur for multi-compartmental microstructures – such as axons and extra-axonal spaces, which we here used in a simple model for the microstructure – and that, for axons parallel to the main magnetic field...

Cell orientation gradients on an inverse opal substrate.

Science.gov (United States)

Lu, Jie; Zou, Xin; Zhao, Ze; Mu, Zhongde; Zhao, Yuanjin; Gu, Zhongze

2015-05-20

The generation of cell gradients is critical for understanding many biological systems and realizing the unique functionality of many implanted biomaterials. However, most previous work can only control the gradient of cell density and this has no effect on the gradient of cell orientation, which has an important role in regulating the functions of many connecting tissues. Here, we report on a simple stretched inverse opal substrate for establishing desired cell orientation gradients. It was demonstrated that tendon fibroblasts on the stretched inverse opal gradient showed a corresponding alignment along with the elongation gradient of the substrate. This "random-to-aligned" cell gradient reproduces the insertion part of many connecting tissues, and thus, will have important applications in tissue engineering.

Response of a core coherent density oscillation on electron cyclotron resonance heating in Heliotron J plasma

Science.gov (United States)

Kobayashi, T.; Kobayashi, S.; Lu, X. X.; Kenmochi, N.; Ida, K.; Ohshima, S.; Yamamoto, S.; Kado, S.; Kokubu, D.; Nagasaki, K.; Okada, H.; Minami, T.; Otani, Y.; Mizuuchi, T.

2018-01-01

We report properties of a coherent density oscillation observed in the core region and its response to electron cyclotron resonance heating (ECH) in Heliotron J plasma. The measurement was performed using a multi-channel beam emission spectroscopy system. The density oscillation is observed in a radial region between the core and the half radius. The poloidal mode number is found to be 1 (or 2). By modulating the ECH power with 100 Hz, repetition of formation and deformation of a strong electron temperature gradient, which is likely ascribed to be an electron internal transport barrier, is realized. Amplitude and rotation frequency of the coherent density oscillation sitting at the strong electron temperature gradient location are modulated by the ECH, while the poloidal mode structure remains almost unchanged. The change in the rotation velocity in the laboratory frame is derived. Assuming that the change of the rotation velocity is given by the background E × B velocity, a possible time evolution of the radial electric field was deduced.

Acrolein impairs the cholesterol transport functions of high density lipoproteins.

Science.gov (United States)

Chadwick, Alexandra C; Holme, Rebecca L; Chen, Yiliang; Thomas, Michael J; Sorci-Thomas, Mary G; Silverstein, Roy L; Pritchard, Kirkwood A; Sahoo, Daisy

2015-01-01

High density lipoproteins (HDL) are considered athero-protective, primarily due to their role in reverse cholesterol transport, where they transport cholesterol from peripheral tissues to the liver for excretion. The current study was designed to determine the impact of HDL modification by acrolein, a highly reactive aldehyde found in high abundance in cigarette smoke, on the cholesterol transport functions of HDL. HDL was chemically-modified with acrolein and immunoblot and mass spectrometry analyses confirmed apolipoprotein crosslinking, as well as acrolein adducts on apolipoproteins A-I and A-II. The ability of acrolein-modified HDL (acro-HDL) to serve as an acceptor of free cholesterol (FC) from COS-7 cells transiently expressing SR-BI was significantly decreased. Further, in contrast to native HDL, acro-HDL promotes higher neutral lipid accumulation in murine macrophages as judged by Oil Red O staining. The ability of acro-HDL to mediate efficient selective uptake of HDL-cholesteryl esters (CE) into SR-BI-expressing cells was reduced compared to native HDL. Together, the findings from our studies suggest that acrolein modification of HDL produces a dysfunctional particle that may ultimately promote atherogenesis by impairing functions that are critical in the reverse cholesterol transport pathway.

Water-transporting proteins

DEFF Research Database (Denmark)

Zeuthen, Thomas

2010-01-01

. In the K(+)/Cl(-) and the Na(+)/K(+)/2Cl(-) cotransporters, water is entirely cotransported, while water transport in glucose uniporters and Na(+)-coupled transporters of nutrients and neurotransmitters takes place by both osmosis and cotransport. The molecular mechanism behind cotransport of water...... transport. Epithelial water transport is energized by the movements of ions, but how the coupling takes place is uncertain. All epithelia can transport water uphill against an osmotic gradient, which is hard to explain by simple osmosis. Furthermore, genetic removal of aquaporins has not given support...... to osmosis as the exclusive mode of transport. Water cotransport can explain the coupling between ion and water transport, a major fraction of transepithelial water transport and uphill water transport. Aquaporins enhance water transport by utilizing osmotic gradients and cause the osmolarity...

Atmospheric neutrino oscillations from upward throughgoing muon multiple scattering in MACRO

Energy Technology Data Exchange (ETDEWEB)

Ambrosio, M.; Antolini, R.; Bakari, D.; Baldini, A.; Barbarino, G.C.; Barish, B.C.; Battistoni, G.; Becherini, Y.; Bellotti, R.; Bemporad, C.; Bernardini, P.; Bilokon, H.; Bloise, C.; Bower, C.; Brigida, M.; Bussino, S.; Cafagna, F.; Calicchio, M.; Campana, D.; Carboni, M.; Caruso, R.; Cecchini, S.; Cei, F.; Chiarella, V.; Chiarusi, T.; Choudhary, B.C.; Coutu, S.; Cozzi, M.; De Cataldo, G.; Dekhissi, H.; De Marzo, C.; De Mitri, I.; Derkaoui, J.; De Vincenzi, M.; Di Credico, A.; Favuzzi, C.; Forti, C.; Fusco, P.; Giacomelli, G.; Giannini, G.; Giglietto, N.; Giorgini, M.; Grassi, M.; Grillo, A.; Gustavino, C.; Habig, A.; Hanson, K.; Heinz, R.; Iarocci, E.; Katsavounidis, E.; Katsavounidis, I.; Kearns, E.; Kim, H.; Kumar, A.; Kyriazopoulou, S.; Lamanna, E.; Lane, C.; Levin, D.S.; Lipari, P.; Longo, M.J.; Loparco, F.; Maaroufi, F.; Mancarella, G.; Mandrioli, G.; Manzoor, S.; Margiotta, A.; Marini, A.; Martello, D.; Marzari-Chiesa, A.; Mazziotta, M.N.; Michael, D.G.; Mikheyev, S.; Monacelli, P.; Montaruli, T.; Monteno, M.; Mufson, S.; Musser, J.; Nicolo, D.; Nolty, R.; Orth, C.; Osteria, G.; Palamara, O.; Patera, V.; Patrizii, L.; Pazzi, R.; Peck, C.W.; Perrone, L.; Petrera, S.; Popa, V.; Raino, A.; Reynoldson, J.; Ronga, F.; Rrhioua, A.; Satriano, C.; Scapparone, E.; Scholberg, K.; Sciubba, A.; Serra, P.; Sioli, M.; Sirri, G.; Sitta, M.; Spinelli, P.; Spinetti, M.; Spurio, M.; Steinberg, R.; Stone, J.L.; Sulak, L.R.; Surdo, A.; Tarle, G.; Togo, V.; Vakili, M.; Walter, C.W.; Webb, R

2003-07-24

The energy of atmospheric neutrinos detected by MACRO was estimated using multiple Coulomb scattering of upward throughgoing muons. This analysis allows a test of atmospheric neutrino oscillations, relying on the distortion of the muon energy distribution. These results have been combined with those coming from the upward throughgoing muon angular distribution only. Both analyses are independent of the neutrino flux normalization and provide strong evidence, above the 4{sigma} level, in favour of neutrino oscillations.

Density fluctuation measurement at edge and internal transport barriers in JT-60U

International Nuclear Information System (INIS)

Oyama, N; Bruskin, L G; Takenaga, H; Shinohara, K; Isayama, A; Ide, S; Sakamoto, Y; Suzuki, T; Fujita, T; Kamada, Y; Miura, Y

2004-01-01

A new analytical method using a combination of the O-mode reflectometer and a time-dependent two-dimensional full-wave simulation code has been developed for the quantitative evaluation of density fluctuations in JT-60U. Two statistical parameters of the reflectometer signals, fluctuation index (F) and elongation factor (χ), are introduced as measures of the fluctuation amplitude (γ) and the width of the poloidal wave number spectrum (k θ0 ). This method is applied to the edge transport barrier (ETB) and internal transport barrier (ITB). At the transition to the ELM free H-mode phase, analysis suggests that the density fluctuation level reduced from 1.9-3.2% to 0.29-0.44%, while the value of k θ0 changed from 1.6-2.0 to 0.77-0.81 cm -1 in the ETB region. On the other hand, the amplitude of the density fluctuation was evaluated as 1.0-2.0% at the ITB region, even after the formation of the box type ITB. Instead, when a pellet was injected into the plasma with a box type ITB as an external perturbation, a remarkable change in the frequency spectrum was observed. Analysis suggests a reduction in the density fluctuation level to 0.4-0.6% after the pellet injection

Drift-Alfvén wave mediated particle transport in an elongated density depression

Science.gov (United States)

Vincena, Stephen; Gekelman, Walter

2006-06-01

Cross-field particle transport due to drift-Alfvén waves is measured in an elongated density depression within an otherwise uniform, magnetized helium plasma column. The depression is formed by drawing an electron current to a biased copper plate with cross-field dimensions of 28ρs=cs/ωci. The process of density depletion and replenishment via particle flux repeats in a quasiperiodic fashion for the duration of the current collection. The mode structure of the wave density fluctuations in the plane perpendicular to the background magnetic field is revealed using a two-probe correlation technique. The particle flux as a function of frequency is measured using a linear array of Langmuir probes and the only significant transport occurs for waves with frequencies between 15%-25% of the ion cyclotron frequency (measured in the laboratory frame) and with perpendicular wavelengths k ⊥ρs˜0.7. The frequency-integrated particle flux is in rough agreement with observed increases in density in the center of the depletion as a function of time. The experiments are carried out in the Large Plasma Device (LAPD) [Gekelman et al., Rev. Sci. Instrum. 62, 2875 (1991)] at the Basic Plasma Science Facility located at the University of California, Los Angeles.

Look Up for Healing: Embodiment of the Heal Concept in Looking Upward.

Directory of Open Access Journals (Sweden)

N D Leitan

Full Text Available Conceptual processing may not be restricted to the mind. The heal concept has been metaphorically associated with an "up" bodily posture. Perceptual Symbol Systems (PSS theory suggests that this association is underpinned by bodily states which occur during learning and become instantiated as the concept. Thus the aim of this study was to examine whether processing related to the heal concept is promoted by priming the bodily state of looking upwards.We used a mixed 2x2 priming paradigm in which 58 participants were asked to evaluate words as either related to the heal concept or not after being primed to trigger the concept of looking up versus down (Direction--within subjects. A possible dose-response effect of priming was investigated via allocating participants to two 'strengths' of prime, observing an image of someone whose gaze was upward/downward (low strength and observing an image of someone whose gaze was upward/downward while physically tilting their head upwards or downwards in accord with the image (high strength (Strength--between subjects.Participants responded to words related to heal faster than words unrelated to heal across both "Strength" conditions. There was no evidence that priming was stronger in the high strength condition.The present study found that, consistent with a PSS view of cognition, the heal concept is embodied in looking upward, which has important implications for cognition, general health, health psychology, health promotion and therapy.

Paleoclassical electron heat transport

International Nuclear Information System (INIS)

Callen, J.D.

2005-01-01

Radial electron heat transport in low collisionality, magnetically-confined toroidal plasmas is shown to result from paleoclassical Coulomb collision processes (parallel electron heat conduction and magnetic field diffusion). In such plasmas the electron temperature equilibrates along magnetic field lines a long length L, which is the minimum of the electron collision length and a maximum effective half length of helical field lines. Thus, the diffusing field lines induce a radial electron heat diffusivity M ≅ L/(πR 0q ) ∼ 10 >> 1 times the magnetic field diffusivity η/μ 0 ≅ ν e (c/ω p ) 2 . The paleoclassical electron heat flux model provides interpretations for many features of 'anomalous' electron heat transport: magnitude and radial profile of electron heat diffusivity (in tokamaks, STs, and RFPs), Alcator scaling in high density plasmas, transport barriers around low order rational surfaces and near a separatrix, and a natural heat pinch (or minimum temperature gradient) heat flux form. (author)

On the diffusive nature of W7-AS transport

Energy Technology Data Exchange (ETDEWEB)

Stroth, U; Giannone, L.; Erckmann, V; Geist, T; Hartfuss, H J; Jaenicke, R; Kuehner, G; Ringler, H; Sardei, F [Max-Planck-Institut fuer Plasmaphysik, Garching (Germany)

1994-12-31

Particle and energy transport in W7-AS have many aspects which are in qualitative agreement with diffusive transport mechanisms. Unlike in tokamaks, the density profiles are flat in the source-free region and for the electron temperature no profile resilience is observed. A strong dependence of transport on the temperature gradient could be ruled out since agreement between the transport coefficients from steady state and perturbative studies has been observed both, in absolute value and parameter dependences. Furthermore, W7-AS transport was found to be compatible with a gyro-Bohm-like and, hence, local transport model. Similar to tokamaks, however, there are problems in relating the local transport coefficients to local plasma parameters. Especially the degradation of confinement with heating power cannot easily be connected to a local quantity. This difficulty is the subject of this paper. (author) 2 refs., 4 figs.

On the diffusive nature of W7-AS transport

International Nuclear Information System (INIS)

Stroth, U.; Giannone, L.; Erckmann, V.; Geist, T.; Hartfuss, H.J.; Jaenicke, R.; Kuehner, G.; Ringler, H.; Sardei, F.

1993-01-01

Particle and energy transport in W7-AS have many aspects which are in qualitative agreement with diffusive transport mechanisms. Unlike in tokamaks, the density profiles are flat in the source-free region and for the electron temperature no profile resilience is observed. A strong dependence of transport on the temperature gradient could be ruled out since agreement between the transport coefficients from steady state and perturbative studies has been observed both, in absolute value and parameter dependences. Furthermore, W7-AS transport was found to be compatible with a gyro-Bohm-like and, hence, local transport model. Similar to tokamaks, however, there are problems in relating the local transport coefficients to local plasma parameters. Especially the degradation of confinement with heating power cannot easily be connected to a local quantity. This difficulty is the subject of this paper. (author) 2 refs., 4 figs

First-row diatomics: Calculation of the geometry and energetics using self-consistent gradient-functional approximations

International Nuclear Information System (INIS)

Kutzler, F.W.; Painter, G.S.

1992-01-01

A fully self-consistent series of nonlocal (gradient) density-functional calculations has been carried out using the augmented-Gaussian-orbital method to determine the magnitude of gradient corrections to the potential-energy curves of the first-row diatomics, Li 2 through F 2 . Both the Langreth-Mehl-Hu and the Perdew-Wang gradient-density functionals were used in calculations of the binding energy, bond length, and vibrational frequency for each dimer. Comparison with results obtained in the local-spin-density approximation (LSDA) using the Vosko-Wilk-Nusair functional, and with experiment, reveals that bond lengths and vibrational frequencies are rather insensitive to details of the gradient functionals, including self-consistency effects, but the gradient corrections reduce the overbinding commonly observed in the LSDA calculations of first-row diatomics (with the exception of Li 2 , the gradient-functional binding-energy error is only 50--12 % of the LSDA error). The improved binding energies result from a large differential energy lowering, which occurs in open-shell atoms relative to the diatomics. The stabilization of the atom arises from the use of nonspherical charge and spin densities in the gradient-functional calculations. This stabilization is negligibly small in LSDA calculations performed with nonspherical densities

Representing or defecting ? : the pursuit of individual upward mobility in low status groups

NARCIS (Netherlands)

Bleeker, Dennis

2010-01-01

This dissertation investigated the conditions under which the individual upward mobility of mem-bers of low status groups is likely to succeed and when it is likely to meet resistance. In addition, it examines how upwardly mobile individuals can create such beneficial conditions. The results

Transport simulations of a density limit in radiation-dominated tokamak discharges: Profile effects

International Nuclear Information System (INIS)

Stotler, D.P.

1988-06-01

The density limit observed in tokamak experiments is thought to be due to a radiative collapse of the current channel. A transport code coupled with an MHD equilibrium routine is used to determine the detailed, self-consistent evolution of the plasma profiles in tokamak discharges with radiated power close to or equalling the input power. The present work is confined to ohmic discharges in steady state. It is found that the shape of the density profile can have a significant impact on the variation of the maximum electron density with plasma current. Analytic calculations confirm this result. 41 refs., 9 figs

Transport simulations of a density limit in radiation-dominated tokamak discharges: profile effects

International Nuclear Information System (INIS)

Stotler, D.P.

1988-01-01

The density limit observed in tokamak experiments is thought to be due to a radiative collapse of the current channel. A transport code coupled with a magnetohydrodynamic (MHD) equilibrium routine is used to determine the detailed, self-consistent evolution of the plasma profiles in tokamak discharges with radiated power close to or equaling the input power. The present work is confined to Ohmic discharges in steady state. It is found that the shape of the density profile can have a significant impact on the variation of the maximum electron density with plasma current. Analytic calculations confirm this result

Self-organization of intracellular gradients during mitosis

Directory of Open Access Journals (Sweden)

Fuller Brian G

2010-01-01

Full Text Available Abstract Gradients are used in a number of biological systems to transmit spatial information over a range of distances. The best studied are morphogen gradients where information is transmitted over many cell lengths. Smaller mitotic gradients reflect the need to organize several distinct events along the length of the mitotic spindle. The intracellular gradients that characterize mitosis are emerging as important regulatory paradigms. Intracellular gradients utilize intrinsic auto-regulatory feedback loops and diffusion to establish stable regions of activity within the mitotic cytosol. We review three recently described intracellular mitotic gradients. The Ran GTP gradient with its elaborate cascade of nuclear transport receptors and cargoes is the best characterized, yet the dynamics underlying the robust gradient of Ran-GTP have received little attention. Gradients of phosphorylation have been observed on Aurora B kinase substrates both before and after anaphase onset. In both instances the phosphorylation gradient appears to result from a soluble gradient of Aurora B kinase activity. Regulatory properties that support gradient formation are highlighted. Intracellular activity gradients that regulate localized mitotic events bare several hallmarks of self-organizing biologic systems that designate spatial information during pattern formation. Intracellular pattern formation represents a new paradigm in mitotic regulation.

Rotation and transport in Alcator C-Mod ITB plasmas

Science.gov (United States)

Fiore, C. L.; Rice, J. E.; Podpaly, Y.; Bespamyatnov, I. O.; Rowan, W. L.; Hughes, J. W.; Reinke, M.

2010-06-01

Internal transport barriers (ITBs) are seen under a number of conditions in Alcator C-Mod plasmas. Most typically, radio frequency power in the ion cyclotron range of frequencies (ICRFs) is injected with the second harmonic of the resonant frequency for minority hydrogen ions positioned off-axis at r/a > 0.5 to initiate the ITBs. They can also arise spontaneously in ohmic H-mode plasmas. These ITBs typically persist tens of energy confinement times until the plasma terminates in radiative collapse or a disruption occurs. All C-Mod core barriers exhibit strongly peaked density and pressure profiles, static or peaking temperature profiles, peaking impurity density profiles and thermal transport coefficients that approach neoclassical values in the core. The strongly co-current intrinsic central plasma rotation that is observed following the H-mode transition has a profile that is peaked in the centre of the plasma and decreases towards the edge if the ICRF power deposition is in the plasma centre. When the ICRF resonance is placed off-axis, the rotation develops a well in the core region. The central rotation continues to decrease as long as the central density peaks when an ITB develops. This rotation profile is flat in the centre (0 ITB density profile is observed (0.5 ITB foot that is sufficiently large to stabilize ion temperature gradient instabilities that dominate transport in C-Mod high density plasmas.

Live transport of Yellow Perch and Nile Tilapia in AQUI-S 20E (10% Eugenol) at high loading densities

Science.gov (United States)

Cupp, Aaron R.; Schreier, Theresa M.; Schleis, Sue M.

2017-01-01

Fish transport costs are a substantial portion of the operational expenses for aquaculture facilities in the USA. Safely transporting higher loading densities of fish would benefit haulers by increasing efficiency and reducing costs, but research evaluating transport for individual species is generally lacking. In this study, Yellow Perch Perca flavescens and Nile Tilapia Oreochromis niloticus were transported for 6 h immersed in water containing AQUI-S 20E (10% eugenol) at fish loading densities of 240 g/L (2 lb/gal) for perch and 480 g/L (4 lb/gal) for tilapia. Survival was quantified for fish transported in AQUI-S 20E concentrations of (1) control or 0 mg/L of water, (2) 100 mg/L, or (3) 200 mg/L. Yellow Perch had 98–100% survival, and Nile Tilapia had 100% survival up to through 14 d after transport across all AQUI-S 20E levels, including the control. Eugenol concentrations decreased rapidly in transport tank water, and fish showed no signs of sedation by the end of transport. We conclude that live transport of Yellow Perch and Nile Tilapia at higher loading densities resulted in high survival regardless of the AQUI-S 20E concentrations we tested.

Density-Gradient Mediated Band Extraction of Leukocytes from Whole Blood Using Centrifugo-Pneumatic Siphon Valving on Centrifugal Microfluidic Discs

Science.gov (United States)

Kearney, Sinéad M.; Kilcawley, Niamh A.; Early, Philip L.; Glynn, Macdara T.; Ducrée, Jens

2016-01-01

Here we present retrieval of Peripheral Blood Mononuclear Cells by density-gradient medium based centrifugation for subsequent analysis of the leukocytes on an integrated microfluidic “Lab-on-a-Disc” cartridge. Isolation of white blood cells constitutes a critical sample preparation step for many bioassays. Centrifugo-pneumatic siphon valves are particularly suited for blood processing as they function without need of surface treatment and are ‘low-pass’, i.e., holding at high centrifugation speeds and opening upon reduction of the spin rate. Both ‘hydrostatically’ and ‘hydrodynamically’ triggered centrifugo-pneumatic siphon valving schemes are presented. Firstly, the geometry of the pneumatic chamber of hydrostatically primed centrifugo-pneumatic siphon valves is optimised to enable smooth and uniform layering of blood on top of the density-gradient medium; this feature proves to be key for efficient Peripheral Blood Mononuclear Cell extraction. A theoretical analysis of hydrostatically primed valves is also presented which determines the optimum priming pressure for the individual valves. Next, ‘dual siphon’ configurations for both hydrostatically and hydrodynamically primed centrifugo-pneumatic siphon valves are introduced; here plasma and Peripheral Blood Mononuclear Cells are extracted through a distinct siphon valve. This work represents a first step towards enabling on disc multi-parameter analysis. Finally, the efficiency of Peripheral Blood Mononuclear Cells extraction in these structures is characterised using a simplified design. A microfluidic mechanism, which we termed phase switching, is identified which affects the efficiency of Peripheral Blood Mononuclear Cell extraction. PMID:27167376

δf simulation of ion neoclassical transport

International Nuclear Information System (INIS)

Wang, W.; Nakajima, N.; Okamoto, M.; Murakami, S.

1999-07-01

Ion neoclassical transport with finite orbit width dynamics is calculated over whole poloidal cross section by using accurate δf method which employs an improved like-particle collision operator and an accurate weighting scheme to solve drift kinetic equation. Ion thermal transport near magnetic axis shows a great reduction from its conventional neoclassical level due to non-standard orbit topology, like that of previous δf simulation. On other hand, the direct particle loss from confinement region may strongly increase ion energy transport near the edge. It is found that ion parallel flow near the axis is also largely reduced due to non-standard orbit topology. In the presence of steep density gradient, ion thermal conductivity is significantly reduced, and an ion particle flux is driven by self-collision alone. (author)

Purification of Sarcocystis neurona sporocysts from opossum (Didelphis virginiana) using potassium bromide discontinuous density gradient centrifugation.

Science.gov (United States)

Elsheikha, Hany M; Murphy, Alice J; Fitzgerald, Scott D; Mansfield, Linda S; Massey, Jeffrey P; Saeed, Mahdi A

2003-06-01

This report describes a new, inexpensive procedure for the rapid and efficient purification of Sarcocystis neurona sporocysts from opossum small intestine. S. neurona sporocysts were purified using a discontinuous potassium bromide density gradient. The procedure provides a source of sporocyst wall and sporozoites required for reliable biochemical characterization and for immunological studies directed at characterizing antigens responsible for immunological responses by the host. The examined isolates were identified as S. neurona using random amplified polymorphic DNA primers and restriction endonuclease digestion assays. This method allows the collection of large numbers of highly purified S. neurona sporocysts without loss of sporocyst viability as indicated by propidium iodide permeability and cell culture infectivity assays. In addition, this technique might also be used for sporocyst purification of other Sarcocystis spp.

Measurement of deuterium density profiles in the H-mode steep gradient region using charge exchange recombination spectroscopy on DIII-D.

Science.gov (United States)

Haskey, S R; Grierson, B A; Burrell, K H; Chrystal, C; Groebner, R J; Kaplan, D H; Pablant, N A; Stagner, L

2016-11-01

Recent completion of a thirty two channel main-ion (deuterium) charge exchange recombination spectroscopy (CER) diagnostic on the DIII-D tokamak [J. L. Luxon, Nucl. Fusion 42, 614 (2002)] enables detailed comparisons between impurity and main-ion temperature, density, and toroidal rotation. In a H-mode DIII-D discharge, these new measurement capabilities are used to provide the deuterium density profile, demonstrate the importance of profile alignment between Thomson scattering and CER diagnostics, and aid in determining the electron temperature at the separatrix. Sixteen sightlines cover the core of the plasma and another sixteen are densely packed towards the plasma edge, providing high resolution measurements across the pedestal and steep gradient region in H-mode plasmas. Extracting useful physical quantities such as deuterium density is challenging due to multiple photoemission processes. These challenges are overcome using a detailed fitting model and by forward modeling the photoemission using the FIDASIM code, which implements a comprehensive collisional radiative model.

Physical mechanism and numerical simulation of the inception of the lightning upward leader

International Nuclear Information System (INIS)

Li Qingmin; Lu Xinchang; Shi Wei; Zhang Li; Zou Liang; Lou Jie

2012-01-01

The upward leader is a key physical process of the leader progression model of lightning shielding. The inception mechanism and criterion of the upward leader need further understanding and clarification. Based on leader discharge theory, this paper proposes the critical electric field intensity of the stable upward leader (CEFISUL) and characterizes it by the valve electric field intensity on the conductor surface, E L , which is the basis of a new inception criterion for the upward leader. Through numerical simulation under various physical conditions, we verified that E L is mainly related to the conductor radius, and data fitting yields the mathematical expression of E L . We further establish a computational model for lightning shielding performance of the transmission lines based on the proposed CEFISUL criterion, which reproduces the shielding failure rate of typical UHV transmission lines. The model-based calculation results agree well with the statistical data from on-site operations, which show the effectiveness and validity of the CEFISUL criterion.

Momentum and scalar transport within a vegetation canopy following atmospheric stability and seasonal canopy changes: the CHATS experiment

Directory of Open Access Journals (Sweden)

S. Dupont

2012-07-01

Full Text Available Momentum and scalar (heat and water vapor transfer between a walnut canopy and the overlying atmosphere are investigated for two seasonal periods (before and after leaf-out, and for five thermal stability regimes (free and forced convection, near-neutral condition, transition to stable, and stable. Quadrant and octant analyses of momentum and scalar fluxes followed by space-time autocorrelations of observations from the Canopy Horizontal Array Turbulence Study's (CHATS thirty meter tower help characterize the motions exchanging momentum, heat, and moisture between the canopy layers and aloft.

During sufficiently windy conditions, i.e. in forced convection, near-neutral and transition to stable regimes, momentum and scalars are generally transported by sweep and ejection motions associated with the well-known canopy-top "shear-driven" coherent eddy structures. During extreme stability conditions (both unstable and stable, the role of these "shear-driven" structures in transporting scalars decreases, inducing notable dissimilarity between momentum and scalar transport.

In unstable conditions, "shear-driven" coherent structures are progressively replaced by "buo-yantly-driven" structures, known as thermal plumes; which appear very efficient at transporting scalars, especially upward thermal plumes above the canopy. Within the canopy, downward thermal plumes become more efficient at transporting scalars than upward thermal plumes if scalar sources are located in the upper canopy. We explain these features by suggesting that: (i downward plumes within the canopy correspond to large downward plumes coming from above, and (ii upward plumes within the canopy are local small plumes induced by canopy heat sources where passive scalars are first injected if there sources are at the same location as heat sources. Above the canopy, these small upward thermal plumes aggregate to form larger scale upward thermal plumes. Furthermore, scalar

A straightforward method for measuring the range of apparent density of microplastics.

Science.gov (United States)

Li, Lingyun; Li, Mengmeng; Deng, Hua; Cai, Li; Cai, Huiwen; Yan, Beizhan; Hu, Jun; Shi, Huahong

2018-10-15

Density of microplastics has been regarded as the primary property that affect the distribution and bioavailability of microplastics in the water column. For measuring the density of microplastis, we developed a simple and rapid method based on density gradient solutions. In this study, we tested four solvents to make the density gradient solutions, i.e., ethanol (0.8 g/cm 3 ), ultrapure water (1.0 g/cm 3 ), saturated NaI (1.8 g/cm 3 ) and ZnCl 2 (1.8 g/cm 3 ). Density of microplastics was measured via observing the float or sink status in the density gradient solutions. We found that density gradient solutions made from ZnCl 2 had a larger uncertainty in measuring density than that from NaI, most likely due to a higher surface tension of ZnCl 2 solution. Solutions made from ethanol, ultrapure water, and NaI showed consistent density results with listed densities of commercial products, indicating that these density gradient solutions were suitable for measuring microplastics with a density range of 0.8-1.8 g/cm 3 . Copyright © 2018 Elsevier B.V. All rights reserved.

An axially averaged-radial transport model of tokamak edge plasmas

International Nuclear Information System (INIS)

Prinja, A.K.; Conn, R.W.

1984-01-01

A two-zone axially averaged-radial transport model for edge plasmas is described that incorporates parallel electron and ion conduction, localized recycling, parallel electron pressure gradient effects and sheath losses. Results for high recycling show that the radial electron temperature profile is determined by parallel electron conduction over short radial distances (proportional 3 cm). At larger radius where Tsub(e) has fallen appreciably, convective transport becomes equally important. The downstream density and ion temperature profiles are very flat over the region where electron conduction dominates. This is seen to result from a sharply decaying velocity profile that follows the radial electron temperature. A one-dimensional analytical recycling model shows that at high neutral pumping rates, the plasma density at the plate, nsub(ia), scales linearly with the unperturbed background density, nsub(io). When ionization dominates nsub(ia)/nsub(io) proportional exp(nsub(io)) while in the intermediate regime nsub(ia)/nsub(io) proportional exp(proportional nsub(io)). Such behavior is qualitatively in accord with experimental observations. (orig.)

Stabilization of the Rayleigh-Taylor instability by convection and thermal conduction in smooth density gradient: WKB analysis

International Nuclear Information System (INIS)

Bud'ko, A.B.; Liberman, M.A.; Bondarenko, E.A.

1992-01-01

Since development of the RT modes in the ablatively accelerated plasma of laser targets imposes crucial limitations on symmetry of spherical implosions and hence on energy cumulation, it has been the subject of intensive numerical and analytical analysis in the recent years, particularly in the context of inertial confinement fusion. Recent thin-foil ablative-acceleration experiments as well as the results of 2D numerical simulations demonstrated substantial reduction of the instability growth rates compared with the classical theory predictions up to the total stabilization in the short-wavelength limit. The numerical results indicated that the main stabilization mechanism is convection. To derive the scaling laws for the RT growth rates and cut-off wavenumbers in the wide range of flow parameters, analytical solutions attract special interest. The analytical approach based on the discontinuity model was developed to analyze the reduction of the RT growth rates by the plasma convective flow and the thermal conductivity effects. The following major problem arises in the discontinuity approximation, which leaves the solution undetermined: the number of the boundary conditions on the perturbed ablation surface is not sufficient to derive the dispersion equation. One needs additional boundary conditions not associated with the conservation laws on the discontinuity surface to close the system of linearized equations for small perturbations. The stabilization effect of highly structured hydrodynamic profiles was studied by Mikaelian and Munro for a stationary plasma. Nevertheless, no reasonable analytical model was constructed taking into account the combined convective, thermal conductivity and density gradient reduction of the RT growth rates. In this report we develop the analytical approach based on the WKB approximation to analyze the stabilization of the RT modes in plasma with smooth density and velocity gradients. (author) 9 refs., 1 fig

Analysis of neoclassical edge plasma transport with gyroviscosity and inertia

International Nuclear Information System (INIS)

Rogister, A.; Antonov, N.

1996-01-01

It is shown that the ambipolarity constraint which results from neoclassical transport theory with gyroviscosity and inertia sets lower limits on the edge density and/or temperature and/or Z eff gradients. Toroidal momentum co, respectively counter, -injection reduces, respectively increases these lower bounds. Generally speaking, co, respectively counter, -injection increases, respectively reduces, the rotation velocities. The theory has so far been developed for the high collisionality regime only. (orig.)

Fueling profile sensitivities of trapped particle mode transport to TNS

International Nuclear Information System (INIS)

Mense, A.T.; Attenberger, S.E.; Houlberg, W.A.

1977-01-01

A key factor in the plasma thermal behavior is the anticipated existence of dissipative trapped particle modes. A possible scheme for controlling the strength of these modes was found. The scheme involves varying the cold fueling profile. A one dimensional multifluid transport code was used to simulate plasma behavior. A multiregime model for particle and energy transport was incorporated based on pseudoclassical, trapped electron, and trapped ion regimes used elsewhere in simulation of large tokamaks. Fueling profiles peaked toward the plasma edge may provide a means for reducing density-gradient-driven trapped particle modes, thus reducing diffusion and conduction losses

Assembly of multiple cell gradients directed by three-dimensional microfluidic channels.

Science.gov (United States)

Li, Yiwei; Feng, Xiaojun; Wang, Yachao; Du, Wei; Chen, Peng; Liu, Chao; Liu, Bi-Feng

2015-08-07

Active control over the cell gradient is essential for understanding biological systems and the reconstitution of the functionality of many types of tissues, particularly for organ-on-a-chip. Here, we propose a three-dimensional (3D) microfluidic strategy for generating controllable cell gradients. In this approach, a homogeneous cell suspension is loaded into a 3D stair-shaped PDMS microchannel to generate a cell gradient within 10 min by sedimentation. We demonstrate that cell gradients of various profiles (exponential and piecewise linear) can be achieved by precisely controlling the height of each layer during the fabrication. With sequential seeding, we further demonstrate the generation of two overlapping cell gradients on the same glass substrate with pre-defined designs. The cell gradient-based QD cytotoxicity assay also demonstrated that cell behaviors and resistances were regulated by the changes in cell density. These results reveal that the proposed 3D microfluidic strategy provides a simple and versatile means for establishing controllable gradients in cell density, opening up a new avenue for reconstructing functional tissues.

Sky glint correction in measurements of upward radiance above the sea surface

Directory of Open Access Journals (Sweden)

Jerzy Olszewski

2000-06-01

Full Text Available An experiment has been performed to determine the upward water-leaving radiance by non-contact measurement of the total upward and downward radiance above the sea surface from a moving ship. The method for achieving this aim is described: the radiance meters are both tilted in such a way that the upward radiance meter can 'see' that part of the measured downward radiance which would be reflected if the water surface were smooth and which is not derived directly from solar glitter. Both meters are firmly fixed in a special frame, which ensures that the required orientation is the most probable one. Time records of the measured parameters are analysed. The results are presented in several forms: frequency (histogram analysis appears to be the most promising one.

Effect of Divalent Cations on RED Performance and Cation Exchange Membrane Selection to Enhance Power Densities.

Science.gov (United States)

Rijnaarts, Timon; Huerta, Elisa; van Baak, Willem; Nijmeijer, Kitty

2017-11-07

Reverse electrodialysis (RED) is a membrane-based renewable energy technology that can harvest energy from salinity gradients. The anticipated feed streams are natural river and seawater, both of which contain not only monovalent ions but also divalent ions. However, RED using feed streams containing divalent ions experiences lower power densities because of both uphill transport and increased membrane resistance. In this study, we investigate the effects of divalent cations (Mg 2+ and Ca 2+ ) on RED and demonstrate the mitigation of those effects using both novel and existing commercial cation exchange membranes (CEMs). Monovalent-selective Neosepta CMS is known to block divalent cations transport and can therefore mitigate reductions in stack voltage. The new multivalent-permeable Fuji T1 is able to transport divalent cations without a major increase in resistance. Both strategies significantly improve power densities compared to standard-grade CEMs when performing RED using streams containing divalent cations.

Role of the vertical pressure gradient in wave boundary layers

DEFF Research Database (Denmark)

Jensen, Karsten Lindegård; Sumer, B. Mutlu; Vittori, Giovanna

2014-01-01

By direct numerical simulation (DNS) of the flow in an oscillatory boundary layer, it is possible to obtain the pressure field. From the latter, the vertical pressure gradient is determined. Turbulent spots are detected by a criterion involving the vertical pressure gradient. The vertical pressure...... gradient is also treated as any other turbulence quantity like velocity fluctuations and statistical properties of the vertical pressure gradient are calculated from the DNS data. The presence of a vertical pressure gradient in the near bed region has significant implications for sediment transport....

Upward creep of the heart: A frequent source of false-positive reversible defects during thallium-201 stress-redistribution SPECT

International Nuclear Information System (INIS)

Friedman, J.; Van Train, K.; Maddahi, J.; Rozanski, A.; Prigent, F.; Bietendorf, J.; Waxman, A.; Berman, D.S.

1989-01-01

A new cause of artifactual 201 Tl defects on single photon emission computed tomography (SPECT) termed upward creep of the heart is described. In 102 consecutive patients undergoing 201 Tl SPECT, 30 (29%) demonstrated upward creep defined by an upward movement of the heart of greater than or equal to 2 pixels during acquisition. In 45 consecutive patients with a less than 5% likelihood of coronary artery disease, 17 (38%) had upward creep. Of these nine had reversible 201 Tl defects localized to the inferior and basal inferoseptal walls, while none of the 28 without upward creep had defects. The 17 low likelihood patients with upward creep had longer exercise duration and higher peak heart rate than those without upward creep. In five additional low likelihood patients with upward creep in whom imaging was immediately repeated, the upward creep pattern disappeared on the repeated images. After we changed our test protocol to begin imaging 15 min postexercise, only five (14%) of 36 low likelihood patients tested demonstrated upward creep. Upward creep is probably related to a transient increase in mean total lung volume early following exhaustive exercise, resulting in a mean lower position of the diaphragm (and thus the heart) at the beginning of imaging. The frequency of this source of false-positive 201 Tl studies can be reduced by delaying SPECT acquisition until 15 min postexercise

Studies of improved electron confinement in low density L-mode National Spherical Torus Experiment discharges

International Nuclear Information System (INIS)

Stutman, D.; Finkenthal, M.; Tritz, K.; Redi, M. H.; Kaye, S. M.; Bell, M. G.; Bell, R. E.; LeBlanc, B. P.; Hill, K. W.; Medley, S. S.; Menard, J. E.; Rewoldt, G.; Wang, W. X.; Synakowski, E. J.; Levinton, F.; Kubota, S.; Bourdelle, C.; Dorland, W.; The NSTX Team

2006-01-01

Electron transport is rapid in most National Spherical Torus Experiment, M. Ono et al., Nucl. Fusion 40, 557 (2000) beam heated plasmas. A regime of improved electron confinement is nevertheless observed in low density L-mode (''low-confinement'') discharges heated by early beam injection. Experiments were performed in this regime to study the role of the current profile on thermal transport. Variations in the magnetic shear profile were produced by changing the current ramp rate and onset of neutral beam heating. An increased electron temperature gradient and local minimum in the electron thermal diffusivity were observed at early times in plasmas with the fastest current ramp and earliest beam injection. In addition, an increased ion temperature gradient associated with a region of reduced ion transport is observed at slightly larger radii. Ultrasoft x-ray measurements of double-tearing magnetohydrodynamic activity, together with current diffusion calculations, point to the existence of negative magnetic shear in the core of these plasmas. Discharges with slower current ramp and delayed beam onset, which are estimated to have more monotonic q-profiles, do not exhibit regions of reduced transport. The results are discussed in the light of the initial linear microstability assessment of these plasmas, which suggests that the growth rate of all instabilities, including microtearing modes, can be reduced by negative or low magnetic shear in the temperature gradient region. Several puzzles arising from the present experiments are also highlighted

Matter effects in upward-going muons and sterile neutrino oscillations

CERN Document Server

Ambrosio, M; Auriemma, G; Bakari, D; Baldini, A; Barbarino, G C; Barish, B C; Battistoni, G; Becherini, Y; Bellotti, R; Bemporad, C; Bernardini, P; Bilokon, H; Bisi, V; Bloise, C; Bower, C; Brigida, M; Bussino, S; Cafagna, F; Calicchio, M; Campana, D; Carboni, M; Caruso, R; Cecchini, S; Cei, F; Chiarella, V; Choudhary, B C; Coutu, S; De Cataldo, G; Dekhissi, H; De Marzo, C; De Mitri, I; Derkaoui, J E; De Vincenzi, M; Di Credico, A; Erriquez, O; Favuzzi, C; Forti, C; Fusco, P; Giacomelli, G; Giannini, G; Giglietto, N; Giorgini, M; Grassi, M; Gray, L; Grillo, A; Guarino, F; Gustavino, C; Habig, A; Hanson, K; Heinz, R; Iarocci, Enzo; Katsavounidis, E; Katsavounidis, I; Kearns, E T; Kim, H; Kyriazopoulou, S; Lammanna, E; Lane, C; Levins, D S; Lipari, P; Longley, N P; Longo, M J; Loparco, F; Maaroufi, F; Mancarella, G; Mandrioli, G; Margiotta, A; Marini, A; Martello, D; Marzari-Chiesa, A; Mazziotta, M N; Michael, D G; Mikheyev, S P; Miller, L; Monacelli, P; Montaruli, T; Monteno, M; Mufson, S L; Musser, J; Nicolò, D; Nolty, R; Orth, C; Osteria, G; Palamara, O; Patera, V; Patrizii, L; Pazzi, R; Peck, C W; Perrone, L; Petrera, S; Pistilli, P; Popa, V; Rainó, A; Reynoldson, J; Ronga, F; Rrhioua, A; Satriano, C; Scapparone, E; Scholberg, K; Sciubba, A; Serra, P; Sioli, M; Sirri, G; Sitta, M; Spinelli, P; Spinetti, M; Spurio, M; Steinberg, R; Stone, J L; Sulak, Lawrence R; Surdo, A; Tarle, G; Togo, V; Vakili, M; Walter, C W; Webb, R

2001-01-01

The angular distribution of upward-going muons produced by atmospheric neutrinos in the rock below the MACRO detector shows anomalies in good agreement with two flavor nu /sub mu / to nu /sub tau / oscillations with maximum mixing and Delta m/sup 2/ around 0.0024 eV/sup 2/. Exploiting the dependence of magnitude of the matter effect on the oscillation channel, and using a set of 809 upward-going muons observed in MACRO, we show that the two flavor nu /sub mu / to nu /sub s/ oscillation is disfavored with 99% C.L. with respect to nu /sub mu / to nu /sub tau /. (29 refs).

Control of Internal Transport Barriers in Magnetically Confined Fusion Plasmas

Science.gov (United States)

Panta, Soma; Newman, David; Sanchez, Raul; Terry, Paul

2016-10-01

In magnetic confinement fusion devices the best performance often involves some sort of transport barriers to reduce the energy and particle flow from core to edge. Those barriers create gradients in the temperature and density profiles. If gradients in the profiles are too steep that can lead to instabilities and the system collapses. Control of these barriers is therefore an important challenge for fusion devices (burning plasmas). In this work we focus on the dynamics of internal transport barriers. Using a simple 7 field transport model, extensively used for barrier dynamics and control studies, we explore the use of RF heating to control the local gradients and therefore the growth rates and shearing rates for barrier initiation and control in self-heated fusion plasmas. Ion channel barriers can be formed in self-heated plasmas with some NBI heating but electron channel barriers are very sensitive. They can be formed in self-heated plasmas with additional auxiliary heating i.e. NBI and radio-frequency(RF). Using RF heating on both electrons and ions at proper locations, electron channel barriers along with ion channel barriers can be formed and removed demonstrating a control technique. Investigating the role of pellet injection in controlling the barriers is our next goal. Work supported by DOE Grant DE-FG02-04ER54741.

Ion temperature gradient mode driven solitons and shocks

Science.gov (United States)

Zakir, U.; Adnan, Muhammad; Haque, Q.; Qamar, Anisa; Mirza, Arshad M.

2016-04-01

Ion temperature gradient (ITG) driven solitons and shocks are studied in a plasma having gradients in the equilibrium number density and equilibrium ion temperature. In the linear regime, it is found that the ion temperature and the ratio of the gradient scale lengths, ηi=Ln/LT , affect both the real frequency and the growth rate of the ITG driven wave instability. In the nonlinear regime, for the first time we derive a Korteweg de Vries-type equation for the ITG mode, which admits solitary wave solution. It is found that the ITG mode supports only compressive solitons. Further, it is noticed that the soliton amplitude and width are sensitive to the parameter ηi=Ln/LT . Second, in the presence of dissipation in the system, we obtain a Burger type equation, which admits the shock wave solution. This work may be useful to understand the low frequency electrostatic modes in inhomogeneous electron-ion plasma having density and ion temperature gradients. For illustration, the model has been applied to tokamak plasma.

Fast ion stabilization of the ion temperature gradient driven modes in the Joint European Torus hybrid-scenario plasmas: a trigger mechanism for internal transport barrier formation

Energy Technology Data Exchange (ETDEWEB)

Romanelli, M; Zocco, A [Euratom/CCFE Fusion Association, Culham Science Centre, Abingdon, Oxon, OX14 3DB (United Kingdom); Crisanti, F, E-mail: Michele.Romanelli@ccfe.ac.u [Associazione Euratom-ENEA sulla Fusione, C.R. Frascati, Frascati (Italy)

2010-04-15

Understanding and modelling turbulent transport in thermonuclear fusion plasmas are crucial for designing and optimizing the operational scenarios of future fusion reactors. In this context, plasmas exhibiting state transitions, such as the formation of an internal transport barrier (ITB), are particularly interesting since they can shed light on transport physics and offer the opportunity to test different turbulence suppression models. In this paper, we focus on the modelling of ITB formation in the Joint European Torus (JET) [1] hybrid-scenario plasmas, where, due to the monotonic safety factor profile, magnetic shear stabilization cannot be invoked to explain the transition. The turbulence suppression mechanism investigated here relies on the increase in the plasma pressure gradient in the presence of a minority of energetic ions. Microstability analysis of the ion temperature gradient driven modes (ITG) in the presence of a fast-hydrogen minority shows that energetic ions accelerated by the ion cyclotron resonance heating (ICRH) system (hydrogen, n{sub H,fast}/n{sub D,thermal} up to 10%, T{sub H,fast}/T{sub D,thermal} up to 30) can increase the pressure gradient enough to stabilize the ITG modes driven by the gradient of the thermal ions (deuterium). Numerical analysis shows that, by increasing the temperature of the energetic ions, electrostatic ITG modes are gradually replaced by nearly electrostatic modes with tearing parity at progressively longer wavelengths. The growth rate of the microtearing modes is found to be lower than that of the ITG modes and comparable to the local E x B-velocity shearing rate. The above mechanism is proposed as a possible trigger for the formation of ITBs in this type of discharges.

Microturbulent drift mode suppression as a trigger mechanism for internal transport barriers on Alcator C-Mod

International Nuclear Information System (INIS)

Zhurovich, K.; Fiore, C.L.; Ernst, D.R.; Bonoli, P.T.; Greenwald, M.J.; Hubbard, A.E.; Hughes, J.W.; Marmar, E.S.; Mikkelsen, D.R.; Phillips, P.; Rice, J.E.

2007-01-01

Internal transport barriers (ITBs) can be routinely produced in enhanced D α (EDA) H-mode discharges on the Alcator C-Mod tokamak by putting the minority ion cyclotron resonance layer at vertical bar r/a vertical bar ≥ 0.5 during the current flat top phase of the discharge. These ITBs are characterized by density peaking at constant temperature and are therefore both particle and energy transport barriers. The ITB formation appears to result from widening the region near the magnetic axis in which toroidal drift modes are stable, allowing the Ware pinch to peak the density profile. Experimental evidence shows that shifting the ICRF resonance off-axis results in a local flattening of ion and electron temperature profiles. TRANSP calculations of ion temperature profiles support this experimentally observed trend. Stability analysis of ion temperature gradient (ITG) and electron temperature gradient modes at times before ITB formation is done using the linear gyrokinetic code GS2. These gyrokinetic calculations find that the most unstable modes in the C-Mod EDA H-mode core, prior to ITB onset, are the toroidal ITG driven type. These modes are suppressed in the ITB region through a temperature gradient reduction when the ICRF resonance is shifted off-axis

Pressure Gradients in the Inner Surf and Outer Swash Zone

Science.gov (United States)

Kidwell, A.; Puleo, J. A.; Torres-Freyermuth, A.

2010-12-01

The swash zone is a highly dynamic region of the beach profile. Although there has been significant progression in understanding the complex hydrodynamics of the swash zone, an improvement in the understanding of the sediment transport mechanisms deserves further investigation. Prior studies have demonstrated that the existing formulations derived from the energetics-type formulation do not accurately and consistently predict sediment transport. Thus, measurements and numerical modeling can contribute in the improvement of the current predictive capability of sediment transport. A potential enhancement to nearshore sediment transport is the horizontal pressure gradient. However, measuring the dynamic pressure gradient in nearshore flows is a difficult task. For instance, standard pressure sensors are generally ill-suited for this type of measurement in shallow swash flows due to the obstructing size of the sensor and the potential for flow interference. With improved measurement apparati and techniques, it is possible to obtain measurements of the horizontal pressure gradient. Our current research includes laboratory and numerical model investigation of the horizontal pressure gradient in the inner surf and outer swash zone. An inexpensive differential pressure gauge is employed allowing for a pressure port on the order of 2 mm diameter. Four pressure sensor pairs are installed 1 cm above the bed with a cross-shore spacing of 8 cm. The sensors are deployed just outside of and at various locations within the outer swash zone to determine spatio-temporal pressure variations. The measurement of total pressure coupled with the corresponding free surface measurements from co-located capacitance wave gauges yields time series of the hydrostatic and dynamic pressure and pressure gradients. A VOF-type RANS model is employed in this investigation. Firstly, the numerical model is validated with swash measurements. Then, model simulations will be performed in order to

Migrational polarization in high-current density molten salt electrochemical devices

Energy Technology Data Exchange (ETDEWEB)

Braunstein, J.; Vallet, C.E.

1977-01-01

Electrochemical flux equations based on the thermodynamics of irreversible processes have been derived in terms of experimental transport coefficients for binary molten salt mixtures analogous to those proposed for high temperature batteries and fuel cells. The equations and some numerical solutions indicate steady state composition gradients of significant magnitude. The effects of migrational separation must be considered along with other melt properties in the characterization of electrode behavior, melt composition, operating temperatures and differences of phase stability, wettability and other physicochemical properties at positive and negative electrodes of high current density devices with mixed electrolytes.

Theory of neoclassical ion temperature-gradient-driven turbulence

Science.gov (United States)

Kim, Y. B.; Diamond, P. H.; Biglari, H.; Callen, J. D.

1991-02-01

The theory of collisionless fluid ion temperature-gradient-driven turbulence is extended to the collisional banana-plateau regime. Neoclassical ion fluid evolution equations are developed and utilized to investigate linear and nonlinear dynamics of negative compressibility ηi modes (ηi≡d ln Ti/d ln ni). In the low-frequency limit (ωB2p. As a result of these modifications, growth rates are dissipative, rather than sonic, and radial mode widths are broadened [i.e., γ˜k2∥c2s(ηi -(2)/(3) )/μi, Δx˜ρs(Bt/Bp) (1+ηi)1/2, where k∥, cs, and ρs are the parallel wave number, sound velocity, and ion gyroradius, respectively]. In the limit of weak viscous damping, enhanced neoclassical polarization persists and broadens radial mode widths. Linear mixing length estimates and renormalized turbulence theory are used to determine the ion thermal diffusivity in both cases. In both cases, a strong favorable dependence of ion thermal diffusivity on Bp (and hence plasma current) is exhibited. Furthermore, the ion thermal diffusivity for long wavelength modes exhibits favorable density scaling. The possible role of neoclassical ion temperature-gradient-driven modes in edge fluctuations and transport in L-phase discharges and the L to H transition is discussed.

Response of Soft Continuous Structures and Topological Defects to a Temperature Gradient.

Science.gov (United States)

Kurita, Rei; Mitsui, Shun; Tanaka, Hajime

2017-09-08

Thermophoresis, which is mass transport induced by a temperature gradient, has recently attracted considerable attention as a new way to transport materials. So far the study has been focused on the transport of discrete structures such as colloidal particles, proteins, and polymers in solutions. However, the response of soft continuous structures such as membranes and gels to a temperature gradient has been largely unexplored. Here we study the behavior of a lamellar phase made of stacked surfactant bilayer membranes under a temperature gradient. We find the migration of membranes towards a low-temperature region, causing the increase in the degree of membrane undulation fluctuations towards that direction. This is contrary to our intuition that the fluctuations are weaker at a lower temperature. We show that this can be explained by temperature-gradient-induced migration of membranes under the topological constraint coming from the connectivity of each membrane. We also reveal that the pattern of an edge dislocation array formed in a wedge-shaped cell can be controlled by a temperature gradient. These findings suggest that application of a temperature gradient provides a novel way to control the organization of soft continuous structures such as membranes, gels, and foams, in a manner essentially different from the other types of fields, and to manipulate topological defects.

Non-contact transportation system of small objects using Ultrasonic Waveguides

International Nuclear Information System (INIS)

Nakamura, K; Koyama, D

2012-01-01

A transportation system for small object or fluid without contact is investigated being based on ultrasonic levitation. Small objects are suspended against gravity at the nodal points in ultrasonic pressure field due to the sound radiation force generated as the gradient of the energy density of the field. In this study, the trapped object is transported in the horizontal plane by introducing the spatial shift of the standing waves by the switching the lateral modes or travelling waves. The goal of the study is to establish a technology which can provide a total system with the flexibility in composing various transportation paths. Methods for linear/rotary stepping motions and continuous linear transportation are explained in this report. All the transportation tracks are composed of a bending vibrator and a reflector. The design for these acoustic cavity/waveguide is discussed.

Stable Computation of the Vertical Gradient of Potential Field Data Based on Incorporating the Smoothing Filters

Science.gov (United States)

Baniamerian, Jamaledin; Liu, Shuang; Abbas, Mahmoud Ahmed

2018-04-01

The vertical gradient is an essential tool in interpretation algorithms. It is also the primary enhancement technique to improve the resolution of measured gravity and magnetic field data, since it has higher sensitivity to changes in physical properties (density or susceptibility) of the subsurface structures than the measured field. If the field derivatives are not directly measured with the gradiometers, they can be calculated from the collected gravity or magnetic data using numerical methods such as those based on fast Fourier transform technique. The gradients behave similar to high-pass filters and enhance the short-wavelength anomalies which may be associated with either small-shallow sources or high-frequency noise content in data, and their numerical computation is susceptible to suffer from amplification of noise. This behaviour can adversely affect the stability of the derivatives in the presence of even a small level of the noise and consequently limit their application to interpretation methods. Adding a smoothing term to the conventional formulation of calculating the vertical gradient in Fourier domain can improve the stability of numerical differentiation of the field. In this paper, we propose a strategy in which the overall efficiency of the classical algorithm in Fourier domain is improved by incorporating two different smoothing filters. For smoothing term, a simple qualitative procedure based on the upward continuation of the field to a higher altitude is introduced to estimate the related parameters which are called regularization parameter and cut-off wavenumber in the corresponding filters. The efficiency of these new approaches is validated by computing the first- and second-order derivatives of noise-corrupted synthetic data sets and then comparing the results with the true ones. The filtered and unfiltered vertical gradients are incorporated into the extended Euler deconvolution to estimate the depth and structural index of a magnetic

The regulation of glucose transport in the heart of control and diabetic rats: With special emphasis on the glucose transporter

International Nuclear Information System (INIS)

Pleta, M. de Leoz.

1989-01-01

Glucose transport regulation with insulin and high perfusion pressure in the perfused rat hearts from control and diabetic rat hearts was investigated. [ 3 H]-cytochalasin B binding assay was used to study the distribution of glucose transporters within the subcellular membranes fractionated by linear sucrose density gradient centrifugation. In the present study, insulin increased glucose uptake in the perfused heart of control and diabetic animals. This coincided with an increase of glucose transporters on the plasma membrane. The increase in glucose transporters on the plasma membrane could not be accounted for by a decrease of glucose transporters from the microsomal membranes. High perfusion pressure did not change the number of glucose transporters on the plasma membrane compared to basal in the control and diabetic animals, though it increased glucose uptake above that observed for insulin in the control. Instead, high perfusion pressure altered the distribution of glucose transporters within the subcellular membranes in reverse to that with insulin, increasing an intermediate membrane pool believed to reside between the plasma membrane and microsomal membranes as well as the intracellular membrane pool

Linking air and water transport in intact soils to macropore characteristics inferred from X-ray computed tomography

DEFF Research Database (Denmark)

Katuwal, S.; Nørgaard, Trine; Møldrup, Per

2015-01-01

Soil macropores often control fluid flow and solute transport, and quantification of macropore characteristics including their variability in space and time are essential to predict soil hydraulic and hydrogeochemical functions. In this study, measurements of air and solute transport properties...... and direct macropore visualization by X-ray CT scanning were carried out on 17 large (19-cm diam.; 20-cm length) undisturbed soil columns sampled across a field site (Silstrup, Denmark) with natural gradients in texture and density. Air permeability (ka) at in-situ water content and -20 hPa of matric......-porosity, suggesting that density is the main control of functional soil structure and gas and solute transport at the Silstrup site. Linking gas transport and chemical tracer experiments with X-ray CT based visualization and quantification of macro-porosity was found to be a powerful method to understand field scale...

A low emittance and uniform density Cs+ source for heavy ion induction linacs

International Nuclear Information System (INIS)

Henestroza, E.; Eylon, S.

1990-01-01

A heavy-ion induction linac experiment (MBE-4) in progress at LBL is studying the transport and acceleration of space-charge-dominated beams in a long alternate gradient focusing channel. Recent studies of the transverse beam dynamics suggested that characteristics of the injector geometry were contributing to the normalized transverse emittance growth. Phase space and current density distribution measurements of the beam extracted from the injector revealed aberrations and a hollow density profile. Based on EGUN calculations the authors redesigned the 10 mA injector for MBE-4 by modifying the cathode: Pierce electrode and using a curved emitting surface. The simulation predicts an extracted beam with less aberrations and a flat density profile. A test stand was used to check the new design. The density profile has measured and found to be in agreement with the numerical simulation

Treatment of Layered Structures Using a Semilocal meta-GGA Density Functional

DEFF Research Database (Denmark)

Madsen, Georg; Ferrighi, Lara; Hammer, Bjørk

2010-01-01

Density functional theory calculations on solids consisting of covalently bonded layers held together by dispersive interactions are presented. Utilizing the kinetic energy density in addition to the density and its gradients gives the meta-generalized gradient approximation (MGGA) M06-L enough...

Poloidal density variation of impurities in a rotating tokamak plasma - flux surface coordinates and effect on transport coefficients

International Nuclear Information System (INIS)

Romanelli, M.

1999-09-01

The poloidal variation of impurity densities over magnetic surfaces brings about an enhancement of neoclassical transport coefficients, as shown by Romanelli and Ottaviani for impurities in the Pfirsch Schlueter regime and by Helander for particles in the banana-plateau regime, both in a large aspect ratio tokamak. The same effect will occur in a finite aspect ratio tokamak and therefore it is considered to be relevant for inclusion in transport codes for comparison with the experimental measurements of impurity transport. Here an expression for the impurity-density poloidal-variation generated by the fast toroidal rotation of the plasma column is presented in general coordinates. (author)

Transvascular low-density lipoprotein transport in patients with diabetes mellitus (type 2)

DEFF Research Database (Denmark)

Kornerup, Karen; Nordestgaard, Børge Grønne; Feldt-Rasmussen, Bo

2002-01-01

accumulation and, thus, atherosclerosis. METHODS AND RESULTS: We developed an in vivo method for measurement of transvascular transport of low density lipoprotein (LDL) and applied it in 16 patients with maturity-onset diabetes (type 2) and 29 healthy control subjects. Autologous 131I-labeled LDL...... plasma insulin levels in diabetic patients. CONCLUSIONS: Transvascular LDL transport may be increased in patients with type 2 diabetes. This suggests that lipoprotein flux into the arterial wall is increased in people with diabetes, possibly explaining the accelerated development of atherosclerosis....... in patients with diabetes and control subjects, respectively (P2.5%/h and 5.3+/-1.6%/h (P

Biological amine transport in chromaffin ghosts. Coupling to the transmembrane proton and potential gradients.