WorldWideScience

Sample records for update emp set

  1. Nuclear EMP: key suppression device parameters for EMP hardening

    International Nuclear Information System (INIS)

    Durgin, D.L.; Brown, R.M.

    1975-03-01

    The electrical transients induced by EMP exhibit unique characteristics which differ considerably from transients associated with other phenomena such as lightning, switching, and circuit malfunctions. The suppression techniques developed to handle more common transients, though not necessarily the same devices, can be used for EMP damage protection. The suppression devices used for circuit level EMP protection are referred to as Terminal Protection Devices (TPD). Little detailed data describing the response of TPD's to EMP-related transients have been published. While most vendors publish specifications for TPD performance, there is little standardization of parameters and TPD response models are not available. This lack of parameter standardization has resulted in a proliferation of test data that is sometimes conflicting and often not directly comparable. This paper derives and/or defines a consistent set of parameters based on EMP circuit hardening requirements and on measurable component parameters and is concerned only with use of TPD's to prevent permanent damage. Three sets of parameters pertaining to pertinent TPD functional characteristics were defined as follows: standby parameters, protection parameters, and failure parameters. These parameters are used to evaluate a representative sample of TPD's and the results are presented in matrix form to facilitate the selection of devices for specific hardening problems

  2. Comparative EMP design practices

    International Nuclear Information System (INIS)

    Martin, L.C.

    1975-01-01

    A large amount of effort is devoted to the hardening of systems against various effects. The nuclear electromagnetic pulse (EMP) creates potentially severe protection problems in hardening against electromagnetic effects. Each hardening effort is usually supported through development or application of sets of rules, practices, constraints, etc., which aid in decision-making throughout the design process. Several excerpts from a few sets of EMP design rules and practices taken from relatively independent sources are presented for comparison of essential features and mode of expression. A general objective is to clarify some of the EMP practices present in general EMC work and to encourage further interchange of relevant information. (auth)

  3. Exploring the SDSS Data Set with Linked Scatter Plots. I. EMP, CEMP, and CV Stars

    Energy Technology Data Exchange (ETDEWEB)

    Carbon, Duane F.; Henze, Christopher; Nelson, Bron C., E-mail: Duane.F.Carbon@nasa.gov [NASA Ames Research Center, NASA Advanced Supercomputing Facility, Moffett Field, CA, 94035-1000 (United States)

    2017-02-01

    We present the results of a search for extremely metal-poor (EMP), carbon-enhanced metal-poor (CEMP), and cataclysmic variable (CV) stars using a new exploration tool based on linked scatter plots (LSPs). Our approach is especially designed to work with very large spectrum data sets such as the SDSS, LAMOST, RAVE, and Gaia data sets, and it can be applied to stellar, galaxy, and quasar spectra. As a demonstration, we conduct our search using the SDSS DR10 data set. We first created a 3326-dimensional phase space containing nearly 2 billion measures of the strengths of over 1600 spectral features in 569,738 SDSS stars. These measures capture essentially all the stellar atomic and molecular species visible at the resolution of SDSS spectra. We show how LSPs can be used to quickly isolate and examine interesting portions of this phase space. To illustrate, we use LSPs coupled with cuts in selected portions of phase space to extract EMP stars, CEMP stars, and CV stars. We present identifications for 59 previously unrecognized candidate EMP stars and 11 previously unrecognized candidate CEMP stars. We also call attention to 2 candidate He ii emission CV stars found by the LSP approach that have not yet been discussed in the literature.

  4. Nuclear EMP induced chaos

    International Nuclear Information System (INIS)

    Dance, B.

    1983-01-01

    It is anticipated that a single nuclear explosion, of adequate size, on the outside of the atmosphere would generate a pulse of sufficient intensity to damage communications equipment (including telephones, radio transmitters and receivers), and to disrupt main power supplies. This damage could be done by a very intense, short duration electro-magnetic pulse (EMP). The article discusses the generation and history of EMP, the test facilities that are needed for EMP test, and techniques that can be used to harden equipment against EMP. It is also important to protect extensive systems against EMP. The article points out that fibre-optics are very useful, because they are EMP resistant and a single fibre can also carry a very high data rate

  5. Updating the Psoriatic Arthritis (PsA) Core Domain Set

    DEFF Research Database (Denmark)

    Orbai, Ana-Maria; de Wit, Maarten; Mease, Philip J

    2017-01-01

    OBJECTIVE: To include the patient perspective in accordance with the Outcome Measures in Rheumatology (OMERACT) Filter 2.0 in the updated Psoriatic Arthritis (PsA) Core Domain Set for randomized controlled trials (RCT) and longitudinal observational studies (LOS). METHODS: At OMERACT 2016, research...... conducted to update the PsA Core Domain Set was presented and discussed in breakout groups. The updated PsA Core Domain Set was voted on and endorsed by OMERACT participants. RESULTS: We conducted a systematic literature review of domains measured in PsA RCT and LOS, and identified 24 domains. We conducted...... and breakout groups at OMERACT 2016 in which findings were presented and discussed. The updated PsA Core Domain Set endorsed with 90% agreement by OMERACT 2016 participants included musculoskeletal disease activity, skin disease activity, fatigue, pain, patient's global assessment, physical function, health...

  6. Principles and techniques of radiation hardening. Volume 3. Electromagnetic pulse (EMP) and system generated EMP

    International Nuclear Information System (INIS)

    Rudie, N.J.

    1976-01-01

    The three-volume book is intended to serve as a review of the effects of thermonuclear explosion induced radiation (x-rays, gamma rays, and beta particles) and the resulting electromagnetic pulse (EMP). Volume 3 deals with the following topics: selected fundamentals of electromagnetic theory; EMP induced currents on antennas and cables; the EMP response of electronics; EMP hardening; EMP testing; injection currents; internal electromagnetic pulse (IEMP); replacement currents; and system generated electromagnetic pulse (SGEMP) hardening

  7. Nuclear EMP: ingredients of an EMP protection engineering methodology

    International Nuclear Information System (INIS)

    Latorre, V.R.; Spogen, L.R. Jr.

    1977-02-01

    A fundamental methodology of electromagnetic pulse (EMP) protection engineering is described. Operations performed within the framework of this methodology are discussed. These operations, along with problem constraints and data, constitute the essential ingredients needed to implement the overall engineering methodology. Basic definitions and descriptions of these essential ingredients are provided. The issues discussed represent the first step in developing a methodology for protecting systems against EMP effects

  8. Improved precision and accuracy for microarrays using updated probe set definitions

    Directory of Open Access Journals (Sweden)

    Larsson Ola

    2007-02-01

    Full Text Available Abstract Background Microarrays enable high throughput detection of transcript expression levels. Different investigators have recently introduced updated probe set definitions to more accurately map probes to our current knowledge of genes and transcripts. Results We demonstrate that updated probe set definitions provide both better precision and accuracy in probe set estimates compared to the original Affymetrix definitions. We show that the improved precision mainly depends on the increased number of probes that are integrated into each probe set, but we also demonstrate an improvement when the same number of probes is used. Conclusion Updated probe set definitions does not only offer expression levels that are more accurately associated to genes and transcripts but also improvements in the estimated transcript expression levels. These results give support for the use of updated probe set definitions for analysis and meta-analysis of microarray data.

  9. Bioelectromagnetic effects of EMP: Preliminary findings

    Science.gov (United States)

    Aldrich, T. E.; Easterly, C. E.; Gailey, P. C.; Hamilton, C. B.

    1988-06-01

    Facilities to simulate electromagnetic pulses (EMPs) are used to test military equipment and electrical communications devices for resistance to the effects of an EMP caused by an upper-atmospheric nuclear detonation. The rapid rise time and high field strengths (0.1 to 50 kV/m) of an EMP distinguish it from other electromagnetic phenomena. Certain types of EMP simulators also expose facility operators and members of the public to electromagnetic fields of varying intensity as do other natural sources such as the fields produced near a lightning bolt. Limited biological effects data have been collected to assess the potential EMP health hazards to humans. Evidence from the available database does not establish that EMPs represent either an occupational or a public health hazard. A critique is presented of the EMP research published to date in order to explore its limitations and similarities with related outcome experience from other electromagnetic field research. Laboratory research and multiple years of observations on workers in existing EMP manufacturing and simulation facilities suggest that there are no acute or short-term health effects. The occupational exposure guideline for EMP is 100 kV/m, which is far in excess of usual exposures with EMP simulators.

  10. EMP Fusion

    OpenAIRE

    KUNTAY, Isık

    2010-01-01

    This paper introduces a novel fusion scheme, called EMP Fusion, which has the promise of achieving breakeven and realizing commercial fusion power. The method is based on harnessing the power of an electromagnetic pulse generated by the now well-developed flux compression technology. The electromagnetic pulse acts as a means of both heating up the plasma and confining the plasma, eliminating intermediate steps. The EMP Fusion device is simpler compared to other fusion devices and this reduces...

  11. EMP protection technology interchange

    International Nuclear Information System (INIS)

    Martin, L.C.

    1977-01-01

    Investigation and assessment of the potential degrading and destructive effects associated with the nuclear electromagnetic (EMP) phenomena has created a large technological base. This base is indeed quite broad owing to the unique and system-pervasive character of the EMP. One of the aims of an emerging discipline, such as that associated with EMP, is to provide for adequate transfer and integration of the developing technology into the overall engineering community. The needs of the community and how EMP hardening and protection information can be transferred or exchanged are reviewed. Many of the current and generally available sources of information are listed, examples of interchange methods are provided, and problems of developing specifications, standards, and suitable guidelines for design and incorporation of protection are also discussed

  12. EMP coupling to ships

    International Nuclear Information System (INIS)

    Deadrick, F.J.; Cabayan, H.S.; Kunz, K.F.; Bevensee, R.M.; Martin, L.C.; Egbert, R.W.

    1980-01-01

    Scale-model tests were conducted to establish the adequacy and limitations of model measurements as tools for predicting electromagnetic pulse (EMP) coupling voltages and currents to the critical antennas, cables, and metallic structures on ships. The scale-model predictions are compared with the results of the full-scale EMP simulation test of the Canadian ASW ship, HMCS Huron. (The EMP coupling predictions in this report were made without prior knowledge of the results of the data from the HMCS Huron tests.) This report establishes that the scale-model tests in conjunction with the data base from EMP coupling modules provides the necessary information for source model development and permits effective, low-cost study of particular system configurations. 184 figures, 9 tables

  13. Power system EMP protection. Final report

    International Nuclear Information System (INIS)

    Marable, J.H.; Barnes, P.R.; Nelson, D.B.

    1975-05-01

    Voltage transients induced in electric power lines and control circuits by the electromagnetic pulse (EMP) from high-altitude nuclear detonations may cause widespread power failure and damage in electric power systems. This report contains a parametric study of EMP power line surges and discusses protective measures to minimize their effects. Since EMP surges have considerably greater rates of rise than lightning surges, recommended standards and test procedures are given to assure that surge arresters protect equipment from damage by EMP. Expected disturbances and damage to power systems are reviewed, and actions are presented which distribution companies can take to counter them. These include backup communications methods, stockpiling of vulnerable parts, repair procedures, and dispatcher actions to prevent blackout from EMP-caused instabilities. A long-range program is presented for improving distributors' protection against EMP. This involves employee training, hardware protection for power and control circuits, and improvement of plans for emergency action. (U.S.)

  14. Nuclear magnetohydrodynamic EMP, solar storms, and substorms

    International Nuclear Information System (INIS)

    Rabinowitz, M.; Meliopoulous, A.P.S.; Glytsis, E.N.

    1992-01-01

    In addition to a fast electromagnetic pulse (EMP), a high altitude nuclear burst produces a relatively slow magnetohydrodynamic EMP (MHD EMP), whose effects are like those from solar storm geomagnetically induced currents (SS-GIC). The MHD EMP electric field E approx-lt 10 - 1 V/m and lasts approx-lt 10 2 sec, whereas for solar storms E approx-gt 10 - 2 V/m and lasts approx-gt 10 3 sec. Although the solar storm electric field is lower than MHD EMP, the solar storm effects are generally greater due to their much longer duration. Substorms produce much smaller effects than SS-GIC, but occur much more frequently. This paper describes the physics of such geomagnetic disturbances and analyzes their effects

  15. Endothelial microparticles (EMP in physiology and pathology

    Directory of Open Access Journals (Sweden)

    Ewa Sierko

    2015-08-01

    Full Text Available Endothelial microparticles (EMP are released from endothelial cells (ECs in the process of activation and/or apoptosis. They harbor adhesive molecules, enzymes, receptors and cytoplasmic structures and express a wide range of various constitutive antigens, typical for ECs, at their surface. Under physiological conditions the concentration of EMP in the blood is clinically insignificant. However, it was reported that under pathological conditions EMP concentration in the blood might slightly increase and contribute to blood coagulation, angiogenesis and inflammation. It has been shown that EMP directly and indirectly contribute to the activation of blood coagulation. Endothelial microparticles directly participate in blood coagulation through their surface tissue factor (TF – a major initiator of blood coagulation. Furthermore, EMP exhibit procoagulant potential via expression of negatively charged phospholipids at their surface, which may promote assembly of coagulation enzymes (TF/VII, tenases and prothrombinase complexes, leading to thrombus formation. In addition, they provide a binding surface for coagulation factors: IXa, VIII, Va and IIa. Moreover, it is possible that EMP transfer TF from TF-bearing EMP to activated platelets and monocytes by binding them through adhesion molecules. Also, EMP express von Willebrand factor, which may facilitate platelet aggregation. Apart from their procoagulant properties, it was demonstrated that EMP may express adhesive molecules and metalloproteinases (MMP-2, MMP-9 at their surface and release growth factors, which may contribute to angiogenesis. Additionally, surface presence of C3 and C4 – components of the classical pathway – suggests pro-inflammatory properties of these structures. This article contains a summary of available data on the biology and pathophysiology of endothelial microparticles and their potential role in blood coagulation, angiogenesis and inflammation.

  16. Efficient process migration in the EMPS multiprocessor system

    NARCIS (Netherlands)

    van Dijk, G.J.W.; Gils, van M.J.

    1992-01-01

    The process migration facility in the Eindhoven multiprocessor system (EMPS) is presented. In the EMPS system, mailboxes are used for interprocess communication. These mailboxes provide transparency of location for communicating processes. The major advantages of mailbox communication in the EMPS

  17. An overview of EMP effects and their control

    Science.gov (United States)

    Culligan, A. J.

    1985-09-01

    The environments associated with a nuclear detonation are probably the most extreme of all the environments to which an electronic equipment system may be exposed. One of these environments is related to the electromagnetic pulse (EMP) which represents an intense pulse of radiated electromagnetic energy. The endo-atmospheric EMP is generally not considered a major threat in comparison with other nuclear weapon effects related to blast, thermal phenomena, neutrons, and gamma rays. The situation is different with respect to the exo-atmospheric EMP which has the potential to simultaneously damage communication and allied networks over many thousands of square miles. The present paper is concerned with these EMP effects and the possibilities for protecting equipment from EMP. For such a protection, an understanding of the system's electronic topology is essential, and component/circuit susceptibility levels must be specified. Attention is given to the wire grid model of a strike aircraft, and the simulation of the EMP environment.

  18. EMP/GMD Phase 0 Report, A Review of EMP Hazard Environments and Impacts

    Energy Technology Data Exchange (ETDEWEB)

    Rivera, Michael Kelly [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Backhaus, Scott N. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Woodroffe, Jesse Richard [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Henderson, Michael Gerard [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Bos, Randall J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Nelson, Eric Michael [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Kelic, Andjelka [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-11-01

    The purpose of this study is to determine methods to analyze the hazard environments, impacts, and consequences of different sources of electromagnetic pulse (EMP), including nuclear electromagnetic pulse (NEMP) and geomagnetic disturbance (GMD) on the U.S. electric power infrastructures and to use those methods to determine EMP and GMD events of concern. The study will be carried out in four phases, each of which will provide higher levels of analytic fidelity that focuses on those EMP/GMD sources and events that create significant consequences, or whose consequences are sufficiently uncertain, to require more in-depth study. This study will leverage the best experimental data; device, equipment and system models; and simulation tools currently available. This study focuses primarily on the bulk electric system (BES) including large generating stations, large power transformers, the transmission network, and transmission system protection. Electrical distribution systems may potentially be included, if warranted, after consideration of the consequences for the bulk power system.

  19. Effects of nuclear electromagnetic pulse (EMP) on synchronous stability of the electric power system

    International Nuclear Information System (INIS)

    Manweiler, R.W.

    1975-11-01

    The effects of a nuclear electromagnetic pulse (EMP) on the synchronous stability of the electric power transmission and distribution systems are evaluated. The various modes of coupling of EMP to the power system are briefly discussed, with particular emphasis on those perturbations affecting the synchronous stability of the transmission system. A brief review of the fundamental concepts of the stability problem is given, with a discussion of the general characteristics of transient analysis. A model is developed to represent single sets as well as repetitive sets of multiple faults on the distribution systems, as might be produced by EMP. The results of many numerical stability calculations are presented to illustrate the transmission system's response from different types of perturbations. The important parameters of both multiple and repetitive faults are studied, including the dependence of the response on the size of the perturbed area, the fault density, and the effective impedance between the fault location and the transmission system. Both major load reduction and the effect of the opening of tie lines at the time of perturbation are also studied. We conclude that there is a high probability that EMP can induce perturbations on the distribution networks causing a large portion of the transmission network in the perturbed area to lose synchronism. The result would be an immediate and massive power failure

  20. Effects of nuclear electromagnetic pulse (EMP) on nuclear power plants

    International Nuclear Information System (INIS)

    Barnes, P.R.; Manweiler, R.W.; Davis, R.R.

    1977-09-01

    The electromagnetic pulse (EMP) from a high-altitude nuclear detonation consists of a transient pulse of high intensity electromagnetic fields. These intense fields induce current and voltage transients in electrical conductors. Although most nuclear power plant cables are not directly exposed to these fields, the attenuated EMP fields that propagate into the plant will couple some EMP energy to these cables. The report predicts the probable effects of the EMP transients that could be induced in critical circuits of safety-related systems. It was found that the most likely consequence of EMP for nuclear plants is an unscheduled shutdown. EMP could prolong the shutdown period by the unnecessary actuation of certain safety systems. In general, EMP could be a nuisance to nuclear power plants, but it is not considered a serious threat to plant safety

  1. EMP at the Non-Proliferation Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Bell, J. [AWE, Aldermaston (United Kingdom)

    1994-12-31

    This experiment presented an opportunity to field customized equipment designed to detect and record electromagnetic pulse (EMP) emanations from an explosion over a wide frequency range. Any data recorded could be used in conjunction with the seismic methods to further non-proliferation studies. No EMP emanations were detectable from the four sensors deployed outside the tunnel confines.

  2. Methods for Free-Space Ultra-Short Solitary EMP Measurement

    Directory of Open Access Journals (Sweden)

    Petr Drexler

    2006-01-01

    Full Text Available There are some suitable methods for ultra-short solitary electromagnetic pulses (EMP measurement. The EMPs are generated by high power microwave generators. The characteristic of EMPs is high power level (Pmax = 250 MW and very short time duration (tp Î <1, 60> ns. Special requirements for measurement methods are placed because of the specific EMPs properties.Two suitable methods for this application are presented in the paper. The first – calorimetric method, utilizes the thermal impacts of microwave absorption. The second method presented – magneto-optic method, use the Faraday’s magneto-optic effect as a sensor principle. It was realized combined calorimetric sensor and there were made some experimental EMP measurements with good results. The sensor utilizing magneto-optic method is in development.

  3. Steroid hormone regulation of EMP2 expression and localization in the endometrium

    Directory of Open Access Journals (Sweden)

    Williams Carmen J

    2008-04-01

    Full Text Available Abstract Background The tetraspan protein epithelial membrane protein-2 (EMP2, which mediates surface display of diverse proteins, is required for endometrial competence in blastocyst implantation, and is uniquely correlated with poor survival from endometrial adenocarcinoma tumors. Because EMP2 is differentially expressed in the various stages of the murine and human estrous cycle, we tested the hypothesis that the steroid hormones progesterone and estrogen influence EMP2 expression and localization. Methods Frozen human proliferative and secretory endometrium were collected and analyzed for EMP2 expression using SDS-PAGE/Western blot analysis. The response of EMP2 to progesterone and estradiol was determined using a combination of real-time PCR, SDS-PAGE/Western blot analysis, and confocal immunofluorescence in the human endometrial carcinoma cell line RL95-2. To confirm the in vitro results, ovariectomized mice were treated with progesterone or estradiol, and EMP2 expression was analyzed using immunohistochemistry. Results Within normal human endometrium, EMP2 expression is upregulated in the secretory phase relative to the proliferative phase. To understand the role of steroid hormones on EMP2 expression, we utilized RL95-2 cells, which express both estrogen and progesterone receptors. In RL95-2 cells, both estradiol and progesterone induced EMP2 mRNA expression, but only progesterone induced EMP2 protein expression. To compare steroid hormone regulation of EMP2 between humans and mice, we analyzed EMP2 expression in ovarectomized mice. Similar to results observed in humans, progesterone upregulated endometrial EMP2 expression and induced EMP2 translocation to the plasma membrane. Estradiol did not promote translocation to the cell surface, but moderately induced EMP2 expression in cytoplasmic compartments in vivo. Conclusion These findings suggest that targeting of EMP2 to specific locations under the influence of these steroid hormones may

  4. Experimental investigation on EMP effect of SRAM

    International Nuclear Information System (INIS)

    Han Jun; Xie Yanzhao; Zhai Aibin; Yao Zhibin

    2010-01-01

    The response of SRAM with different memory size at different read/write state was studied under EMP environment with pulse width of 50 ns, 350 ns and 1μs.The electric field amplitude of EMP ranges from 2.5 to 40 kV/m. It was found that the upset number has no obvious relation with memory size of SRAM and band width of EMP. The electric field amplitude is the crucial parameter leading to the upset effects. Further more, the upset effects of SRAM at read write state was much more seriously compared to the SRAM was not at read/write state. (authors)

  5. Performa Supply Chain Emping Melinjo di Kabupaten Bantul Daerah Istimewa Yogyakarta

    Directory of Open Access Journals (Sweden)

    Eni Istiyanti

    2017-07-01

    Full Text Available Emping melinjo was one of the agroindustry-products that had great potential to be developed. The industry of emping melinjo contributed more on economic growth in the reason of creating jobs and alleviate poverty. The purpose of this study was to describe the performance of supply chain of emping melinjo from upstream to downstream and analyze the efficiency of supply chain of emping melinjo in Bantul regency. Field study to obtain primary data was done through interviews with the practitioners of emping melinjo supply chain (including farmers and merchants of melinjo as well as producers and retailers of melinjo chips. The results of field studies then tabulated and analyzed descriptively and quantitatively using Linear Programming. The analysis showed that there were 37 supply chain networks of emping melinjo in Bantul. The practitioners of upstream supply chain were melinjo farmers, middlemen, traders, wholesalers, and retailers, while in the downstream, were emping melinjo producers, traders, small traders, wholesalers, retailers and consumers. The activities of the doer of emping melinjo supply chain includes purchasing, sales, harvesting, packaging, packing, stripping, storage, loading and unloading, transporting, sorting and grading. The flow of products and money in the supply chain of emping melinjo run smoothly, while the flow of information was sluggish. Based on linear programming analysis the cost of supply chain of emping melinjo would reach minimum level at Rp33,969,264 per week if the production of emping melinjo as many as 25 361 kg per week wich was distributed using 22 networks.

  6. Design of a bounded wave EMP (Electromagnetic Pulse) simulator

    Science.gov (United States)

    Sevat, P. A. A.

    1989-06-01

    Electromagnetic Pulse (EMP) simulators are used to simulate the EMP generated by a nuclear weapon and to harden equipment against the effects of EMP. At present, DREO has a 1 m EMP simulator for testing computer terminal size equipment. To develop the R and D capability for testing larger objects, such as a helicopter, a much bigger threat level facility is required. This report concerns the design of a bounded wave EMP simulator suitable for testing large size equipment. Different types of simulators are described and their pros and cons are discussed. A bounded wave parallel plate type simulator is chosen for it's efficiency and the least environmental impact. Detailed designs are given for 6 m and 10 m parallel plate type wire grid simulators. Electromagnetic fields inside and outside the simulators are computed. Preliminary specifications for a pulse generator required for the simulator are also given. Finally, the electromagnetic fields radiated from the simulator are computed and discussed.

  7. EMP protection procedure for electrical/electronic systems

    International Nuclear Information System (INIS)

    Latorre, V.R.

    1976-01-01

    This paper presents a procedure for the protection engineer to follow in assessing a system with respect to its susceptibility to an electromagnetic pulse (EMP), and in determining whether the system requires protection. If the system is determined to be vulnerable to EMP, the procedure also indicates how to decide upon the most suitable protection scheme. The discussion centers on two flow charts, which illustrate the step-by-step procedure which utilizes the necessary ingredients of EMP protection engineering discussed in a previous paper. The description of the protection procedure is divided into two parts: the first dealing with issues on the macroscopic or large-scale system level, while the second is concerned with operations on the subsystem level or lower

  8. Did high-altitude EMP (electromagnetic pulse) cause the Hawaiian streetlight incident

    Energy Technology Data Exchange (ETDEWEB)

    Vittitoe, C N

    1989-04-01

    Studies of electromagnetic pulse (EMP) effects on civilian and military systems predict results ranging from severe destruction to no damage. Convincing analyses that support either extreme are rare. The Hawaiian streetlight incident associated with the Starfish nuclear burst is the most widely quoted observed damage. We review the streetlight characteristics and estimate the coupling between the Starfish EMP and a particular streetlight circuit identified as one of the few that failed. Evidence indicates that the damage was EMP-generated. The main contributing factors were the azimuthal angle of the circuit relative to the direction of EMP propagation, and the rapid rise of the EMP signal. The azimuthal angle provided coherent buildup of voltage as the EMP swept across the transmission line. The rapid rise allowed substantial excitation before the canceling effects of ground reflections limited the signals. Resulting voltages were at the threshold for causing the observed fuse damage and are consistent with this damage occurring in only some of the strings in the systems. 15 refs., 16 figs., 4 tabs.

  9. 78 FR 35073 - Compass Efficient Model Portfolios, LLC and Compass EMP Funds Trust; Notice of Application

    Science.gov (United States)

    2013-06-11

    ... Balanced Fund, Compass EMP Multi-Asset Growth Fund, Compass EMP Alternative Strategies Fund, Compass EMP Balanced Volatility Weighted Fund, Compass EMP Growth Volatility Weighted Fund, and Compass EMP... Efficient Model Portfolios, LLC and Compass EMP Funds Trust; Notice of Application June 4, 2013. AGENCY...

  10. Nuclear EMP induced chaos. [Effect of nuclear explosion on power and communication facilities

    Energy Technology Data Exchange (ETDEWEB)

    Dance, B

    1983-04-01

    It is anticipated that a single nuclear explosion, of adequate size, on the outside of the atmosphere would generate a pulse of sufficient intensity to damage communications equipment (including telephones, radio transmitters and receivers), and to disrupt main power supplies. This damage could be done by a very intense, short duration electro-magnetic pulse (EMP). The article discusses the generation and history of EMP, the test facilities that are needed for EMP test, and techniques that can be used to harden equipment against EMP. It is also important to protect extensive systems against EMP. The article points out that fibre-optics are very useful, because they are EMP resistant and a single fibre can also carry a very high data rate.

  11. A Survey of Graduates of Combined Emergency Medicine-Pediatrics Residency Programs: An Update.

    Science.gov (United States)

    Strobel, Ashley M; Chasm, Rose M; Woolridge, Dale P

    2016-10-01

    In 1998, emergency medicine-pediatrics (EM-PEDS) graduates were no longer eligible for the pediatric emergency medicine (PEM) sub-board certification examination. There is a paucity of guidance regarding the various training options for medical students who are interested in PEM. We sought to to determine attitudes and personal satisfaction of graduates from EM-PEDS combined training programs. We surveyed 71 graduates from three EM-PEDS residences in the United States. All respondents consider their combined training to be an asset when seeking a job, 92% find it to be an asset to their career, and 88% think it provided added flexibility to job searches. The most commonly reported shortcoming was their ineligibility for the PEM sub-board certification. The lack of this designation was perceived to be a detriment to securing academic positions in dedicated children's hospitals. When surveyed regarding which training offers the better skill set for the practice of PEM, 90% (44/49) stated combined EM-PEDS training. When asked which training track gives them the better professional advancement in PEM, 52% (23/44) chose combined EM-PEDS residency, 27% (12/44) chose a pediatrics residency followed by a PEM fellowship, and 25% (11/44) chose an EM residency then a PEM fellowship. No EM-PEDS respondents considered PEM fellowship training after the completion of the dual training program. EM-PEDS graduates found combined training to be an asset in their career. They felt that it provided flexibility in job searches, and that it was ideal training for the skill set required for the practice of PEM. EM-PEDS graduates' practices varied, including mixed settings, free-standing children's hospitals, and community emergency departments. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. EMP Threats to US National Security: Congressional Responses

    Science.gov (United States)

    Huessy, Peter

    2011-04-01

    The US Congress is considering how best to respond to concerns that EMP is a real and present danger to US security. The threats come from a variety of areas: solar storms, non-nuclear EMP from man-made machines and devices; and nuclear EMP from a nuclear device exploded above CONUS or other critical areas important to the United States and its allies. Responses have to date included passage in the House of legislation to protect the electrical grid in the United States from such threats and hearings before the Homeland Security Committee. Additional efforts include examining missile defense responses, protection of the maritime domain, and hardening of US military and related civilian infrastructure. The House of Representatives has also examined what Europe, the European Union and NATO, both government and private industry, have done in these areas. Complicating matters are related issues of cyber-security and overall homeland security priorities.

  13. Nuclear EMP simulation for large-scale urban environments. FDTD for electrically large problems.

    Energy Technology Data Exchange (ETDEWEB)

    Smith, William S. [Los Alamos National Laboratory; Bull, Jeffrey S. [Los Alamos National Laboratory; Wilcox, Trevor [Los Alamos National Laboratory; Bos, Randall J. [Los Alamos National Laboratory; Shao, Xuan-Min [Los Alamos National Laboratory; Goorley, John T. [Los Alamos National Laboratory; Costigan, Keeley R. [Los Alamos National Laboratory

    2012-08-13

    In case of a terrorist nuclear attack in a metropolitan area, EMP measurement could provide: (1) a prompt confirmation of the nature of the explosion (chemical or nuclear) for emergency response; and (2) and characterization parameters of the device (reaction history, yield) for technical forensics. However, urban environment could affect the fidelity of the prompt EMP measurement (as well as all other types of prompt measurement): (1) Nuclear EMP wavefront would no longer be coherent, due to incoherent production, attenuation, and propagation of gamma and electrons; and (2) EMP propagation from source region outward would undergo complicated transmission, reflection, and diffraction processes. EMP simulation for electrically-large urban environment: (1) Coupled MCNP/FDTD (Finite-difference time domain Maxwell solver) approach; and (2) FDTD tends to be limited to problems that are not 'too' large compared to the wavelengths of interest because of numerical dispersion and anisotropy. We use a higher-order low-dispersion, isotropic FDTD algorithm for EMP propagation.

  14. A cross-country Exchange Market Pressure (EMP dataset

    Directory of Open Access Journals (Sweden)

    Mohit Desai

    2017-06-01

    Full Text Available The data presented in this article are related to the research article titled - “An exchange market pressure measure for cross country analysis” (Patnaik et al. [1]. In this article, we present the dataset for Exchange Market Pressure values (EMP for 139 countries along with their conversion factors, ρ (rho. Exchange Market Pressure, expressed in percentage change in exchange rate, measures the change in exchange rate that would have taken place had the central bank not intervened. The conversion factor ρ can interpreted as the change in exchange rate associated with $1 billion of intervention. Estimates of conversion factor ρ allow us to calculate a monthly time series of EMP for 139 countries. Additionally, the dataset contains the 68% confidence interval (high and low values for the point estimates of ρ’s. Using the standard errors of estimates of ρ’s, we obtain one sigma intervals around mean estimates of EMP values. These values are also reported in the dataset.

  15. A cross-country Exchange Market Pressure (EMP) dataset.

    Science.gov (United States)

    Desai, Mohit; Patnaik, Ila; Felman, Joshua; Shah, Ajay

    2017-06-01

    The data presented in this article are related to the research article titled - "An exchange market pressure measure for cross country analysis" (Patnaik et al. [1]). In this article, we present the dataset for Exchange Market Pressure values (EMP) for 139 countries along with their conversion factors, ρ (rho). Exchange Market Pressure, expressed in percentage change in exchange rate, measures the change in exchange rate that would have taken place had the central bank not intervened. The conversion factor ρ can interpreted as the change in exchange rate associated with $1 billion of intervention. Estimates of conversion factor ρ allow us to calculate a monthly time series of EMP for 139 countries. Additionally, the dataset contains the 68% confidence interval (high and low values) for the point estimates of ρ 's. Using the standard errors of estimates of ρ 's, we obtain one sigma intervals around mean estimates of EMP values. These values are also reported in the dataset.

  16. Updating the Psoriatic Arthritis (PsA) Core Domain Set: A Report from the PsA Workshop at OMERACT 2016.

    Science.gov (United States)

    Orbai, Ana-Maria; de Wit, Maarten; Mease, Philip J; Callis Duffin, Kristina; Elmamoun, Musaab; Tillett, William; Campbell, Willemina; FitzGerald, Oliver; Gladman, Dafna D; Goel, Niti; Gossec, Laure; Hoejgaard, Pil; Leung, Ying Ying; Lindsay, Chris; Strand, Vibeke; van der Heijde, Désirée M; Shea, Bev; Christensen, Robin; Coates, Laura; Eder, Lihi; McHugh, Neil; Kalyoncu, Umut; Steinkoenig, Ingrid; Ogdie, Alexis

    2017-10-01

    To include the patient perspective in accordance with the Outcome Measures in Rheumatology (OMERACT) Filter 2.0 in the updated Psoriatic Arthritis (PsA) Core Domain Set for randomized controlled trials (RCT) and longitudinal observational studies (LOS). At OMERACT 2016, research conducted to update the PsA Core Domain Set was presented and discussed in breakout groups. The updated PsA Core Domain Set was voted on and endorsed by OMERACT participants. We conducted a systematic literature review of domains measured in PsA RCT and LOS, and identified 24 domains. We conducted 24 focus groups with 130 patients from 7 countries representing 5 continents to identify patient domains. We achieved consensus through 2 rounds of separate surveys with 50 patients and 75 physicians, and a nominal group technique meeting with 12 patients and 12 physicians. We conducted a workshop and breakout groups at OMERACT 2016 in which findings were presented and discussed. The updated PsA Core Domain Set endorsed with 90% agreement by OMERACT 2016 participants included musculoskeletal disease activity, skin disease activity, fatigue, pain, patient's global assessment, physical function, health-related quality of life, and systemic inflammation, which were recommended for all RCT and LOS. These were important, but not required in all RCT and LOS: economic cost, emotional well-being, participation, and structural damage. Independence, sleep, stiffness, and treatment burden were on the research agenda. The updated PsA Core Domain Set was endorsed at OMERACT 2016. Next steps for the PsA working group include evaluation of PsA outcome measures and development of a PsA Core Outcome Measurement Set.

  17. The integrated circuit IC EMP transient state disturbance effect experiment method investigates

    International Nuclear Information System (INIS)

    Li Xiaowei

    2004-01-01

    Transient state disturbance characteristic study on the integrated circuit, IC, need from its coupling path outset. Through cable (aerial) coupling, EMP converts to an pulse current voltage and results in the impact to the integrated circuit I/O orifice passing the cable. Aiming at the armament system construction feature, EMP effect to the integrated circuit, IC inside the system is analyzed. The integrated circuit, IC EMP effect experiment current injection method is investigated and a few experiments method is given. (authors)

  18. Promoter Hypermethylation of the EMP3 Gene in a Series of 229 Human Gliomas

    Directory of Open Access Journals (Sweden)

    Marta Mellai

    2013-01-01

    Full Text Available The epithelial membrane protein 3 (EMP3 is a candidate tumor suppressor gene in the critical region 19q13.3 for several solid tumors, including tumors of the nervous systems. The aim of this study was to investigate the EMP3 promoter hypermethylation status in a series of 229 astrocytic and oligodendroglial tumors and in 16 GBM cell lines. The analysis was performed by methylation-specific PCR and capillary electrophoresis. Furthermore, the EMP3 expression at protein level was evaluated by immunohistochemistry and Western blotting analysis. Associations of EMP3 hypermethylation with total 1p/19q codeletion, MGMT promoter hypermethylation, IDH1/IDH2 and TP53 mutations, and EGFR amplification were studied, as well as its prognostic significance. The EMP3 promoter hypermethylation has been found in 39.5% of gliomas. It prevailed in low-grade tumors, especially in gliomas with an oligodendroglial component, and in sGBMs upon pGBMs. In oligodendroglial tumors, it was strongly associated with both IDH1/IDH2 mutations and total 1p/19q codeletion and inversely with EGFR gene amplification. No association was found with MGMT hypermethylation and TP53 mutations. In the whole series, the EMP3 hypermethylation status correlated with 19q13.3 loss and lack of EMP3 expression at protein level. A favorable prognostic significance on overall survival of the EMP3 promoter hypermethylation was found in patients with oligodendroglial tumors.

  19. The EMP excitation of radiation by the pulsed relativistic electron beam

    International Nuclear Information System (INIS)

    Balakirev, V.A.; Sidelnikov, G.L.

    1996-01-01

    The mechanisms of excitation of ultra-wideband electromagnetic pulses (EMP) by short pulses of high-current relativistic electron beams were proposed and investigated. It is shown that the transformation efficiency of the bunch kinetic energy to the excited energy of the EMP can be very significant. (author). 2 figs., 4 refs

  20. The EMP excitation of radiation by the pulsed relativistic electron beam

    Energy Technology Data Exchange (ETDEWEB)

    Balakirev, V A; Sidelnikov, G L [Kharkov Inst. of Physics and Technology (Russian Federation)

    1997-12-31

    The mechanisms of excitation of ultra-wideband electromagnetic pulses (EMP) by short pulses of high-current relativistic electron beams were proposed and investigated. It is shown that the transformation efficiency of the bunch kinetic energy to the excited energy of the EMP can be very significant. (author). 2 figs., 4 refs.

  1. sae is essential for expression of the staphylococcal adhesins Eap and Emp.

    Science.gov (United States)

    Harraghy, Niamh; Kormanec, Jan; Wolz, Christiane; Homerova, Dagmar; Goerke, Christiane; Ohlsen, Knut; Qazi, Saara; Hill, Philip; Herrmann, Mathias

    2005-06-01

    Eap and Emp are two Staphylococcus aureus adhesins initially described as extracellular matrix binding proteins. Eap has since emerged as being important in adherence to and invasion of eukaryotic cells, as well as being described as an immunomodulator and virulence factor in chronic infections. This paper describes the mapping of the transcription start point of the eap and emp promoters. Moreover, using reporter-gene assays and real-time PCR in defined regulatory mutants, environmental conditions and global regulators affecting expression of eap and emp were investigated. Marked differences were found in expression of eap and emp between strain Newman and the 8325 derivatives SH1000 and 8325-4. Moreover, both genes were repressed in the presence of glucose. Analysis of expression of both genes in various regulatory mutants revealed that sarA and agr were involved in their regulation, but the data suggested that there were additional regulators of both genes. In a sae mutant, expression of both genes was severely repressed. sae expression was also reduced in the presence of glucose, suggesting that repression of eap and emp in glucose-containing medium may, in part, be a consequence of a decrease in expression of sae.

  2. Análisis semiótico en secuencias de interacción empáticas y no empáticas: un estudio microgenético

    Directory of Open Access Journals (Sweden)

    Pablo Fossa

    Full Text Available Resumen Este estudio tuvo por objetivo explorar y describir el proceso de regulación dialógica en interacciones conversacionales. Se registraron en video treinta díadas de estudiantes desconocidos entre sí en interacciones que tuvieron una manipulación orientada a generar una situación empática o bien no-empática. Se seleccionaron cuatro segmentos de conversación, dos por cada tipo de interacción. El texto fue analizado con un protocolo de análisis semiótico basado en el modelo de análisis propuesto por (Molina, 2007. Los resultados muestran que las interacciones empáticas se caracterizan por un proceso de coconstrucción de significados, con una adecuada administración de la tensión y una identificación con el signo lingüístico. Por otra parte, las interacciones no empáticas se caracterizan por la emergencia de signos lingüísticos que no continúan la secuencia de construcción de significados; con una alta tensión dialógica, y una estrategia de distanciamiento o abandono del campo de significado.

  3. Emp is a component of the nuclear matrix of mammalian cells and undergoes dynamic rearrangements during cell division

    International Nuclear Information System (INIS)

    Bala, Shashi; Kumar, Ajay; Soni, Shivani; Sinha, Sudha; Hanspal, Manjit

    2006-01-01

    Emp, originally detected in erythroblastic islands, is expressed in numerous cell types and tissues suggesting a functionality not limited to hematopoiesis. To study the function of Emp in non-hematopoietic cells, an epitope-tagged recombinant human Emp was expressed in HEK cells. Preliminary studies revealed that Emp partitioned into both the nuclear and Triton X-100-insoluble cytoskeletal fractions in approximately a 4:1 ratio. In this study, we report investigations of Emp in the nucleus. Sequential extractions of interphase nuclei showed that recombinant Emp was present predominantly in the nuclear matrix. Immunofluorescence microscopy showed that Emp was present in typical nuclear speckles enriched with the spliceosome assembly factor SC35 and partially co-localized with actin staining. Coimmunoprecipitation and GST-pull-down assays confirmed the apparent close association of Emp with nuclear actin. During mitosis, Emp was detected at the mitotic spindle/spindle poles, as well as in the contractile ring during cytokinesis. These results suggest that Emp undergoes dynamic rearrangements within the nuclear architecture that are correlated with cell division

  4. Gel shift analysis of the empA promoter region in Vibrio anguillarum

    Directory of Open Access Journals (Sweden)

    Denkin Steven M

    2004-10-01

    Full Text Available Abstract Background The induction of metalloprotease encoded by empA in Vibrio anguillarum occurs at high cell density in salmon intestinal mucus. Previously we have shown that there are significant differences in empA expression in two strains of V. anguillarum, M93Sm and NB10. It is hypothesized that differences in empA regulation are due to differences in binding of regulatory elements. Results Two strains of V. anguillarum, M93Sm and NB10, were examined and compared for the presence of DNA regulatory proteins that bind to and control the empA promoter region. Gel mobility shift assays, using a digoxigenin (DIG-labeled oligomer containing a lux box-like element and the promoter for empA, were done to demonstrate the presence of a DNA-binding protein. Protein extracts from NB10 cells incubated in Luria Bertani broth + 2% NaCl (LB20, nine salts solution + 200 μg/ml mucus (NSSM, 3M (marine minimal medium, or NSS resulted in a gel mobility shift. No gel mobility shift was seen when protein extracts from either LB20- or NSSM-grown M93Sm cells were mixed with the DIG-labeled empA oligomer. The azocasein assay detected protease activity in all incubation conditions for NB10 culture supernatants. In contrast, protease activity was detected in M93Sm culture supernatants only when incubated in NSSM. Since the luxR homologue in V. anguillarum, vanT, has been cloned, sequenced, and shown to be required for protease activity, we wanted to determine if vanT mutants of NB10 exhibit the same gel shift observed in the wild-type. Site-directed mutagenesis was used to create vanT mutants in V. anguillarum M93Sm and NB10 to test whether VanT is involved with the gel mobility shift. Both vanT mutants, M02 and NB02, did not produce protease activity in any conditions. However, protein extracts from NB02 incubated in each condition still exhibited a gel shift when mixed with the DIG-labeled empA oligomer. Conclusions The data demonstrate that protein extracts of V

  5. Mesothelioma and other lung disease in taconite miners; the uncertain role of non-asbestiform EMP.

    Science.gov (United States)

    Mandel, Jeffrey H; Odo, Nnaemeka U

    2018-04-10

    The purpose of this paper was to assess the role of non-asbestiform amphibole EMPs in the etiology of mesotheliomas and other lung disease in taconite (iron ore) miners. Increased mesothelioma rates have been described in Minnesota taconite workers since the late 1990s. Currently, over 100 cases have been reported by the Minnesota Department of Health within the complete cohort of miners in Minnesota. Geologic sampling has indicated that only the eastern part of the iron range contains non-asbestiform amphibole elongate mineral particles (EMPs), in close proximity to the ore. This type of EMP has been less studied and also exists in talc and gold mining. A series of investigations into the state's taconite industry have been recently completed. Results from a cohort mortality study indicated an SMR of 2.77 (95% CI = 1.87-3.96) for mesothelioma. In a case-control study, the odds ratio for mesothelioma for high vs. low EMP exposure was 2.25 (5% CI = 1.13-4.5) but EMPs in this study were counted by phase contrast microscopy. Odds ratios were not elevated in mines located in the eastern part of the Mesabi iron range. The overall findings suggest that mesothelioma in taconite miners is related to EMP exposure. Because of the way EMPs were counted, results from these studies cannot allow a firm conclusion about the association between EMP exposure and the reported excess mesothelioma. Copyright © 2018 Elsevier Inc. All rights reserved.

  6. The value of load shifting. An estimate for Norway using the EMPS model

    International Nuclear Information System (INIS)

    Doorman, Gerard; Wolfgang, Ove

    2006-05-01

    An attempt is made to estimate the value of Load Shifting (LS) in the Norwegian system, using the EMPS model. A thorough update of the demand side model and cost estimates used in the model was done as a preparation for the project, and the report gives a comprehensive description of the demand models used. The LS measure that is analyzed is moving 600 MW demand in Norway from peak to lower demand hours during the day. The value of this was estimated both in a simplified manner (based on simulated price differences between these periods), and by simulations with the EMPS model and a subsequent calculation of the socio-economic surplus. Neither approaches showed any significant value. The results do not necessarily mean that the value in reality is zero - there are a number of limitations in the model which make it difficult to estimate the real value, like the representation of wind generation, demand variability, outages, exchange prices with continental Europe, flexibility of hydro and thermal generation, reserves and elasticity of demand in the short run. It was verified through sensitivity calculations that especially increasing reserve requirements and increasing the variability of wind generation increased price differences and therefore the value of LS. A number of improvements in the EMPS model and data are proposed to obtain a more suitable simulation model for this kind of analyses: 1) modeling of reserves, 2) representation of wind variability, 3) thermal generation models, 4) differentiation between long and short term price elasticity, 5) review of interconnection capacities, 6) use of quadratic losses and the 7) representation of more stochastic factors like e.g. outages in the simulations. Although the model at present clearly has its limitations with respect to estimating the value of LS, it appears that price differences between spot prices in the actual hours in reality are small. Comparison with Nord Pool spot prices for the years 2003

  7. Studies of Effect Analysis of Electromagnetic Pulses (EMP) in Operating Nuclear Power Plants (NPP)

    Energy Technology Data Exchange (ETDEWEB)

    Ye, Song Hae; Ryu, Ho Sun; Kim, Min Yi; Lee, Eui Jong [KHNP, Daejeon (Korea, Republic of)

    2016-05-15

    The effect analysis of electromagnetic pulses (EMPs) has been studied for the past year by the Central Research Institute of Korea Hydro Nuclear Power Co. (KHNP) in order to better establish safety measures in operating nuclear power plants. What is an electromagnetic pulse (EMP)? As a general term for high-power electromagnetic radiation, it refers to strong electromagnetic pulses that destroy only electronic equipment devices in a short period without loss of life. The effect analysis of EMPs in operating NPPs and their corresponding safety measures in terms of selecting target devices against EMP impact have been examined in this paper. In general, domestic nuclear power plants do apply the design of fail-safe concepts. For example, if key instruments of a system fail because of EMPs, the control rods of a nuclear reactor are dropped automatically in order to maintain safe conditions of the NPP. Reactor cooling presents no problem because the diesel generator will adopt the analog starting circuit least affected by the electromagnetic waves.

  8. The Establishment of Object Selection Criteria for Effect Analysis of Electromagnetic Pulse (EMP) in Operating Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Ye, Song Hae; Ryu, Hosun; Kim, Minyi; Lee, Euijong [KHNP CRI, Daejeon (Korea, Republic of)

    2016-10-15

    The electromagnetic pulse (EMP) can be used as a strategic weapon by inducing damaging voltage and currents that the electrical circuits are not designed to withstand. EMPs are lethal to electronic systems. All EMP events have three common components: a source, coupling path, and receptor. It can also travel across power grids, destroying electronics as it passes in less than a second. There have been no research studies on the effect analysis for EMP in domestic nuclear power plants and power grids. To ensure the safety of operating nuclear power plants in this environment, the emission of EMP is needed for the effect analysis and safety measures against EMPs. Actually, it is difficult and inefficient to conduct the effect analysis of EMP with all the equipment and systems in nuclear power plants (NPPs). Therefore, this paper presents the results of establishing the object selection criteria for the effect analysis of EMP in operating nuclear power plants through reviewing previous research in the US and the safety related design concepts in domestic NPPs. It is not necessary to ensure the continued operation of the plant in intense multiple EMP environments. The most probable effect of EMP on a modern nuclear power plant is an unscheduled shutdown. EMP may also cause an extended shutdown by the unnecessary activation of some safety related systems. In general, EMP can be considered a nuisance to nuclear plants, but it is not considered a serious threat to plant safety. The results of EMP effect analysis show less possibility of failure in the tested individual equipment. It was also confirmed that there is no possibility of simultaneous failure for devices in charge of the safety shutdown in the NPP.

  9. Development of a new EMP code at LANL

    Science.gov (United States)

    Colman, J. J.; Roussel-Dupré, R. A.; Symbalisty, E. M.; Triplett, L. A.; Travis, B. J.

    2006-05-01

    A new code for modeling the generation of an electromagnetic pulse (EMP) by a nuclear explosion in the atmosphere is being developed. The source of the EMP is the Compton current produced by the prompt radiation (γ-rays, X-rays, and neutrons) of the detonation. As a first step in building a multi- dimensional EMP code we have written three kinetic codes, Plume, Swarm, and Rad. Plume models the transport of energetic electrons in air. The Plume code solves the relativistic Fokker-Planck equation over a specified energy range that can include ~ 3 keV to 50 MeV and computes the resulting electron distribution function at each cell in a two dimensional spatial grid. The energetic electrons are allowed to transport, scatter, and experience Coulombic drag. Swarm models the transport of lower energy electrons in air, spanning 0.005 eV to 30 keV. The swarm code performs a full 2-D solution to the Boltzmann equation for electrons in the presence of an applied electric field. Over this energy range the relevant processes to be tracked are elastic scattering, three body attachment, two body attachment, rotational excitation, vibrational excitation, electronic excitation, and ionization. All of these occur due to collisions between the electrons and neutral bodies in air. The Rad code solves the full radiation transfer equation in the energy range of 1 keV to 100 MeV. It includes effects of photo-absorption, Compton scattering, and pair-production. All of these codes employ a spherical coordinate system in momentum space and a cylindrical coordinate system in configuration space. The "z" axis of the momentum and configuration spaces is assumed to be parallel and we are currently also assuming complete spatial symmetry around the "z" axis. Benchmarking for each of these codes will be discussed as well as the way forward towards an integrated modern EMP code.

  10. Kemasan Menarik dan Internet Marketing untuk Meningkatkan Nilai Jual Emping Garut sebagai Produk Unggulan Kabupaten Sragen

    Directory of Open Access Journals (Sweden)

    Sari Purnavita

    2018-03-01

    Full Text Available Tanaman garut termasuk dalam jenis umbi-umbian yang banyak ditanam oleh masyarakat yang tinggal di Kecamatan Gesi, Kabupaten Sragen. Di Kabupaten Sragen terdapat beberapa industri rumah tangga emping garut, dua di antaranya yang memiliki motivasi sangat besar untuk berkembang adalah UKM emping garut “Sumber Rejeki” dan UKM emping garut “Fadilah”. Permasalahan kedua UKM adalah keterbatasan inovasi rasa emping garut, kemasan sangat sederhana, dan sistem pemasaran masih tradisional sehingga sehingga omzet penjualan dan nilai jual produk masih rendah. Untuk meningkatkan omzet penjualan dapat dilakukan dengan perbaikan inovasi dan teknologi pengemasan, teknologi seasoning dengan bumbu tabur, dan memperluas pemasaran dengan media internet. Produk emping garut yang dikemas secara menarik, inovasi produk emping garut aneka rasa, dan pemasaran dengan media internet melalui blogspot dapat menenbus pemasaran secara luas baik di toko-toko besar, harga jual produk meningkat 50%,dan omzet penjualan meningkat 100%.

  11. Nuclear EMP: stripline test method for measuring transfer impedance

    International Nuclear Information System (INIS)

    Miller, J.S.

    1975-11-01

    A method for measuring the transfer impedance of flat metal joints for frequencies to 100 MHz has been developed which makes use of striplines. The stripline method, which has similarities to the quadraxial method used for cylindrical components, is described and sets of test results are given. The transfer impedance of a simple joint is modeled as a spurious hyperbolic curve, and a close curve fit to transfer impedance test data from various samples is demonstrated for both the stripline and the quadraxial methods. Validity checks of the test data are discussed using the curve model and other criteria. The method was developed for testing riveted joints which form the avionics bays on B-1s. The joints must provide shielding from EMP currents

  12. Down-regulation of EMP1 is associated with epithelial hyperplasia and metaplasia in nasal polyps.

    Science.gov (United States)

    Yu, Xue Min; Li, Chun Wei; Li, Ying Ying; Liu, Jing; Lin, Zhi Bin; Li, Tian Ying; Zhao, Li; Pan, Xin Liang; Shi, Li; Wang, De Yun

    2013-11-01

    The aim of this study was to assess protein and mRNA expression of epithelial membrane protein 1 (EMP1) in the nasal mucosa of patients with nasal polyps (NP), and to determine what changes occur in response to glucocorticosteroid (GC) treatment. NP tissue was obtained from 55 patients, 18 of whom were treated with nasal GCs (i.e. these 18 patients had NP biopsies taken before and after treatment). Biopsies of inferior turbinate mucosa from 30 healthy subjects were used as controls. Quantitative PCR and immunohistochemistry were performed to determine the expression levels of EMP1. EMP1 mRNA expression was significantly lower (2.77-fold) in tissues from NP patients before GC treatment when compared to controls, but was increased in these patients after GC treatment. EMP1 staining in nasal epithelium co-localized with both basal (p63(+)) and differentiated (CK18(+)) epithelial cells. Their immunoreactivity was significantly greater in controls than NP patients. EMP1 mRNA levels were lower in the epithelium with severe hyperplasia (1.79-fold) or with metaplasia (1.85-fold) as compared to those with mild to moderate hyperplasia or non-metaplastic epithelium, respectively. Positive correlations between EMP1 and other epithelial cell-related gene (e.g. JUN, PTGS2, AREG etc.) mRNAs were observed. EMP1 could be a biomarker for aberrant epithelial remodelling and metaplasia in chronic inflammatory upper airway mucosa (e.g. NP). © 2013 John Wiley & Sons Ltd.

  13. Exponential Megapriming PCR (EMP) Cloning—Seamless DNA Insertion into Any Target Plasmid without Sequence Constraints

    Science.gov (United States)

    Ulrich, Alexander; Andersen, Kasper R.; Schwartz, Thomas U.

    2012-01-01

    We present a fast, reliable and inexpensive restriction-free cloning method for seamless DNA insertion into any plasmid without sequence limitation. Exponential megapriming PCR (EMP) cloning requires two consecutive PCR steps and can be carried out in one day. We show that EMP cloning has a higher efficiency than restriction-free (RF) cloning, especially for long inserts above 2.5 kb. EMP further enables simultaneous cloning of multiple inserts. PMID:23300917

  14. STATIC{sub T}EMP: a useful computer code for calculating static formation temperatures in geothermal wells

    Energy Technology Data Exchange (ETDEWEB)

    Santoyo, E. [Universidad Nacional Autonoma de Mexico, Centro de Investigacion en Energia, Temixco (Mexico); Garcia, A.; Santoyo, S. [Unidad Geotermia, Inst. de Investigaciones Electricas, Temixco (Mexico); Espinosa, G. [Universidad Autonoma Metropolitana, Co. Vicentina (Mexico); Hernandez, I. [ITESM, Centro de Sistemas de Manufactura, Monterrey (Mexico)

    2000-07-01

    The development and application of the computer code STATIC{sub T}EMP, a useful tool for calculating static formation temperatures from actual bottomhole temperature data logged in geothermal wells is described. STATIC{sub T}EMP is based on five analytical methods which are the most frequently used in the geothermal industry. Conductive and convective heat flow models (radial, spherical/radial and cylindrical/radial) were selected. The computer code is a useful tool that can be reliably used in situ to determine static formation temperatures before or during the completion stages of geothermal wells (drilling and cementing). Shut-in time and bottomhole temperature measurements logged during well completion activities are required as input data. Output results can include up to seven computations of the static formation temperature by each wellbore temperature data set analysed. STATIC{sub T}EMP was written in Fortran-77 Microsoft language for MS-DOS environment using structured programming techniques. It runs on most IBM compatible personal computers. The source code and its computational architecture as well as the input and output files are described in detail. Validation and application examples on the use of this computer code with wellbore temperature data (obtained from specialised literature) and with actual bottomhole temperature data (taken from completion operations of some geothermal wells) are also presented. (Author)

  15. Exponential megapriming PCR (EMP cloning--seamless DNA insertion into any target plasmid without sequence constraints.

    Directory of Open Access Journals (Sweden)

    Alexander Ulrich

    Full Text Available We present a fast, reliable and inexpensive restriction-free cloning method for seamless DNA insertion into any plasmid without sequence limitation. Exponential megapriming PCR (EMP cloning requires two consecutive PCR steps and can be carried out in one day. We show that EMP cloning has a higher efficiency than restriction-free (RF cloning, especially for long inserts above 2.5 kb. EMP further enables simultaneous cloning of multiple inserts.

  16. The development of the time dependence of the nuclear EMP electric field

    International Nuclear Information System (INIS)

    Eng, C.

    2009-01-01

    The nuclear electromagnetic pulse (EMP) electric field calculated with the legacy code CHAP is compared with the field given by an integral solution of Maxwell's equations, also known as the Jefimenko equation, to aid our current understanding on the factors that affect the time dependence of the EMP. For a fair comparison the CHAP current density is used as a source in the Jefimenko equation. At first, the comparison is simplified by neglecting the conduction current and replacing the standard atmosphere with a constant density air slab. The simplicity of the resultant current density aids in determining the factors that affect the rise, peak and tail of the EMP electric field versus time. The three dimensional nature of the radiating source, i.e. sources off the line-of-sight, and the time dependence of the derivative of the current density with respect to time are found to play significant roles in shaping the EMP electric field time dependence. These results are found to hold even when the conduction current and the standard atmosphere are properly accounted for. Comparison of the CHAP electric field with the Jefimenko electric field offers a direct validation of the high-frequency/outgoing wave approximation.

  17. Nuclear EMP induced chaos

    Energy Technology Data Exchange (ETDEWEB)

    Dance, B

    1983-08-01

    In the event of nuclear war, the availability of first class communications facilities and of reliable electricity supplies would be of absolutely vital importance to any of the population surviving the first onslaught not only for their own welfare, but also for the preservation of their nation's retaliation deterrent capability. However, it is to be expected that a single nuclear explosion of adequate size on the outside of the atmosphere would generate a pulse of sufficient intensity to damage communications equipment (including telephones, radio transmitters and receivers) and to interrupt main supplies. The situation caused by electromagnetic pulses (EMP) is discussed.

  18. Measures to protect communication systems from EMP effects

    International Nuclear Information System (INIS)

    Stadler, B.

    1977-01-01

    Possible EMP damage in transmitter and receiver elements, including antennas, is dealt with. It is recommendet that these important systems should be installed inside a commercially available Faraday cage for do-it-yourself assembly. (HP) [de

  19. Development of Design Information Template for Nuclear Power Plants for Electromagnetic Pulse (EMP) Effect Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Minyi; Ryu, Hosan; Ye, Songhae; Lee, Euijong [KNHP CRI, Daejeon (Korea, Republic of)

    2016-10-15

    An electromagnetic pulse (EMP) is a transient electromagnetic shock wave that has powerful electric and magnetic fields that can destroy electronic equipment. It is generally well-known that EMPs can cause the malfunction and disorder of electronic equipment and serious damages to electric power systems and communication networks. Research is being carried out to protect nuclear power plants (NPPs) from EMP threats. Penetration routes of EMPs can be roughly categorized into two groups, radioactivity and conductivity. The radioactive effect refers to an impact transmitted to the ground from high-altitude electromagnetic pulses (HEMP). Such an impact may affect target equipment through the point of entry (POE) of the concrete structure of an NPP. The conductive effect refers to induced voltage or current coupled to the NPPs cable structure. The induced voltage and current affect the target equipment via connected cables. All these factors must be considered when taking into account EMP effect analysis for NPPs. To examine all factors, it is necessary to fully understand the schemes of NPPs. This paper presents a four type design information template that can be used to analyze the EMP effect in operating nuclear power plants. In order to analyze of the effects of EMPs on operating NPPs, we must consider both the conductive and radioactive effects on the target (system, equipment, structure). For these reasons, not only the equipment information, but also the information about the structure and the external penetration will be required. We are developing a design information template for robust nuclear design information acquisition. We expect to develop a block diagram on the basis of the template.

  20. Development of Design Information Template for Nuclear Power Plants for Electromagnetic Pulse (EMP) Effect Analysis

    International Nuclear Information System (INIS)

    Kim, Minyi; Ryu, Hosan; Ye, Songhae; Lee, Euijong

    2016-01-01

    An electromagnetic pulse (EMP) is a transient electromagnetic shock wave that has powerful electric and magnetic fields that can destroy electronic equipment. It is generally well-known that EMPs can cause the malfunction and disorder of electronic equipment and serious damages to electric power systems and communication networks. Research is being carried out to protect nuclear power plants (NPPs) from EMP threats. Penetration routes of EMPs can be roughly categorized into two groups, radioactivity and conductivity. The radioactive effect refers to an impact transmitted to the ground from high-altitude electromagnetic pulses (HEMP). Such an impact may affect target equipment through the point of entry (POE) of the concrete structure of an NPP. The conductive effect refers to induced voltage or current coupled to the NPPs cable structure. The induced voltage and current affect the target equipment via connected cables. All these factors must be considered when taking into account EMP effect analysis for NPPs. To examine all factors, it is necessary to fully understand the schemes of NPPs. This paper presents a four type design information template that can be used to analyze the EMP effect in operating nuclear power plants. In order to analyze of the effects of EMPs on operating NPPs, we must consider both the conductive and radioactive effects on the target (system, equipment, structure). For these reasons, not only the equipment information, but also the information about the structure and the external penetration will be required. We are developing a design information template for robust nuclear design information acquisition. We expect to develop a block diagram on the basis of the template

  1. Assessment and mitigation of electromagnetic pulse (EMP) impacts at short-pulse laser facilities

    International Nuclear Information System (INIS)

    Brown, C G Jr; Bond, E; Clancy, T; Dangi, S; Eder, D C; Ferguson, W; Kimbrough, J; Throop, A

    2010-01-01

    The National Ignition Facility (NIF) will be impacted by electromagnetic pulse (EMP) during normal long-pulse operation, but the largest impacts are expected during short-pulse operation utilizing the Advanced Radiographic Capability (ARC). Without mitigation these impacts could range from data corruption to hardware damage. We describe our EMP measurement systems on Titan and NIF and present some preliminary results and thoughts on mitigation.

  2. Empowerment impact assessment (EmpIA), a tool for poverty alleviation and capacity building

    CSIR Research Space (South Africa)

    Louw, MR

    2006-09-01

    Full Text Available their quality of life. xrhombus Facilitate the upgrading of the social and physical environment. xrhombus Increase employment. xrhombus Reduce poverty. xrhombus Stimulate economic growth. xrhombus Reduce imbalances in access to economic opportunities. 1... IMPACT ASSESSMENT (EmpIA), A TOOL FOR POVERTY ALLEVIATION AND CAPACITY BUILDING M.R. LOUW CSIR Built Environment: Pretoria, P.O. Box 395, Pretoria, 0001 ABSTRACT Empowerment impact assessment (EmpIA) is a quantitative...

  3. Probabilistic approach to EMP assessment

    International Nuclear Information System (INIS)

    Bevensee, R.M.; Cabayan, H.S.; Deadrick, F.J.; Martin, L.C.; Mensing, R.W.

    1980-09-01

    The development of nuclear EMP hardness requirements must account for uncertainties in the environment, in interaction and coupling, and in the susceptibility of subsystems and components. Typical uncertainties of the last two kinds are briefly summarized, and an assessment methodology is outlined, based on a probabilistic approach that encompasses the basic concepts of reliability. It is suggested that statements of survivability be made compatible with system reliability. Validation of the approach taken for simple antenna/circuit systems is performed with experiments and calculations that involve a Transient Electromagnetic Range, numerical antenna modeling, separate device failure data, and a failure analysis computer program

  4. A method for visualizing surface-exposed and internal PfEMP1 adhesion antigens in Plasmodium falciparum infected erythrocytes

    Directory of Open Access Journals (Sweden)

    Arnot David E

    2008-06-01

    Full Text Available Abstract Background The insertion of parasite antigens into the host erythrocyte membrane and the structure and distribution of Plasmodium falciparum adhesion receptors on that membrane are poorly understood. Laser scanning confocal microscopy (LSCM and a novel labelling and fixation method have been used to obtain high resolution immuno-fluorescent images of erythrocyte surface PfEMP1 and internal antigens which allow analysis of the accumulation of PfEMP1 on the erythrocyte membrane during asexual development. Methods A novel staining technique has been developed which permits distinction between erythrocyte surface PfEMP1 and intracellular PfEMP1, in parasites whose nuclear material is exceptionally well resolved. Primary antibody detection by fluorescence is carried out on the live parasitized erythrocyte. The surface labelled cells are then fixed using paraformaldehyde and permeabilized with a non-ionic detergent to permit access of antibodies to internal parasite antigens. Differentiation between surface and internal antigens is achieved using antibodies labelled with different fluorochromes and confocal microscopy Results Surface exposed PfEMP1 is first detectable by antibodies at the trophozoite stage of intracellular parasite development although the improved detection method indicates that there are differences between different laboratory isolates in the kinetics of accumulation of surface-exposed PfEMP1. Conclusion A sensitive method for labelling surface and internal PfEMP1 with up to three different fluorochromes has been developed for laser scanning confocal optical microscopy and the analysis of the developmental expression of malaria adhesion antigens.

  5. Transistor collector breakdown in the presence of conducted EMP and gamma radiation

    International Nuclear Information System (INIS)

    Rice, D.H.

    1975-01-01

    In this paper we develop expressions which describe breakdown, negative resistance and latch characteristics for a common emitter transistor when exposed to simultaneous conducted EMP and ionizing radiation. These expressions are derived from a modified Ebers-Moll model and show that common emitter breakdown voltage is reduced, latch (or sustaining voltage) remains unchanged, and that the negative resistance characteristics are changed. Using the modified Ebers-Moll model good agreement between predicted and observed circuit response is demonstrated when the circuits are exposed to a rising collector voltage (due to EMP) and simultaneous ionizing (gamma) radiation

  6. Methodology to assess the effects of magnetohydrodynamic electromagnetic pulse (MHD-EMP) on power systems

    International Nuclear Information System (INIS)

    Legro, J.R.; Abi-Samra, N.C.; Crouse, J.C.; Tesche, F.M.

    1985-01-01

    This paper summarizes a method to evaluate the possible effects of magnetohydrodynamic-electromagnetic pulse (MHD-EMP) on power systems. This method is based on the approach adapted to study the impact of geomagnetic storms on power systems. The paper highlights the similarities and differences between the two phenomena. Also presented are areas of concern which are anticipated from MHD-EMP on the overall system operation. 12 refs., 1 fig

  7. Adaptive Fault Detection for Complex Dynamic Processes Based on JIT Updated Data Set

    Directory of Open Access Journals (Sweden)

    Jinna Li

    2012-01-01

    Full Text Available A novel fault detection technique is proposed to explicitly account for the nonlinear, dynamic, and multimodal problems existed in the practical and complex dynamic processes. Just-in-time (JIT detection method and k-nearest neighbor (KNN rule-based statistical process control (SPC approach are integrated to construct a flexible and adaptive detection scheme for the control process with nonlinear, dynamic, and multimodal cases. Mahalanobis distance, representing the correlation among samples, is used to simplify and update the raw data set, which is the first merit in this paper. Based on it, the control limit is computed in terms of both KNN rule and SPC method, such that we can identify whether the current data is normal or not by online approach. Noted that the control limit obtained changes with updating database such that an adaptive fault detection technique that can effectively eliminate the impact of data drift and shift on the performance of detection process is obtained, which is the second merit in this paper. The efficiency of the developed method is demonstrated by the numerical examples and an industrial case.

  8. Interface Control Document for the EMPACT Module that Estimates Electric Power Transmission System Response to EMP-Caused Damage

    Energy Technology Data Exchange (ETDEWEB)

    Werley, Kenneth Alan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Mccown, Andrew William [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)ory

    2016-06-26

    The EPREP code is designed to evaluate the effects of an Electro-Magnetic Pulse (EMP) on the electric power transmission system. The EPREP code embodies an umbrella framework that allows a user to set up analysis conditions and to examine analysis results. The code links to three major physics/engineering modules. The first module describes the EM wave in space and time. The second module evaluates the damage caused by the wave on specific electric power (EP) transmission system components. The third module evaluates the consequence of the damaged network on its (reduced) ability to provide electric power to meet demand. This third module is the focus of the present paper. The EMPACT code serves as the third module. The EMPACT name denotes EMP effects on Alternating Current Transmission systems. The EMPACT algorithms compute electric power transmission network flow solutions under severely damaged network conditions. Initial solutions are often characterized by unacceptible network conditions including line overloads and bad voltages. The EMPACT code contains algorithms to adjust optimally network parameters to eliminate network problems while minimizing outages. System adjustments include automatically adjusting control equipment (generator V control, variable transformers, and variable shunts), as well as non-automatic control of generator power settings and minimal load shedding. The goal is to evaluate the minimal loss of customer load under equilibrium (steady-state) conditions during peak demand.

  9. An update: choice architecture as a means to change eating behaviour in self-service settings

    DEFF Research Database (Denmark)

    Skov, Laurits Rohden; Perez-Cueto, Armando

    2014-01-01

    Objective: The primary objective of this review was to update the current evidence-base for the use of choice architecture as a means to change eating behaviour in self-service eating settings, hence potentially reducing energy intake. Methodology: 12 databases were searched systematically for ex...... in the topic of choice architecture and nudging has increased the scientific output since the last review. There is a clear limitation in the lack of a clear definitions and theoretical foundation....

  10. Transparência e Replicabilidade na Pesquisa Empírica em Direito: conceitos e ferramentas

    OpenAIRE

    Oliveira, Paulo

    2018-01-01

    Com o crescimento das pesquisas empíricas em Direito quais as práticas devem ser adotadas pelos pesquisadores para acompanhar o Padrão Ouro da pesquisa? Quais os conceitos necessários para que a Pesquisa Empírica possa crescer de forma sustentável e democrática? Esse artigo tenta delinear alguns conceitos importantes da Ciência 2.0 e mostra algumas das principais ferramentas para atingir plenamente o ideal de Ciência Aberta.

  11. Overproduction, purification and crystallization of a chondroitin sulfate A-binding DBL domain from a Plasmodium falciparum var2csa-encoded PfEMP1 protein

    International Nuclear Information System (INIS)

    Higgins, Matthew K.

    2008-01-01

    A chondroitin sulfate A-binding DBL important in placental malaria has been overproduced, purified and crystallized. Diffraction data were collected to 1.9 Å resolution. The PfEMP1 proteins of the malaria parasite Plasmodium falciparum are inserted into the membrane of infected red blood cells, where they mediate adhesion to a variety of human receptors. The DBL domains of the var2csa-encoded PfEMP1 protein play a critical role in malaria of pregnancy, tethering infected cells to the surface of the placenta through interactions with the glycosaminoglycan carbohydrate chondroitin sulfate A (CSA). A CSA-binding DBL domain has been overproduced in a bacterial expression system, purified and crystallized. Native data sets extending to 1.9 Å resolution have been collected and phasing is under way

  12. Overproduction, purification and crystallization of a chondroitin sulfate A-binding DBL domain from a Plasmodium falciparum var2csa-encoded PfEMP1 protein

    Energy Technology Data Exchange (ETDEWEB)

    Higgins, Matthew K., E-mail: mkh20@cam.ac.uk [Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA (United Kingdom)

    2008-03-01

    A chondroitin sulfate A-binding DBL important in placental malaria has been overproduced, purified and crystallized. Diffraction data were collected to 1.9 Å resolution. The PfEMP1 proteins of the malaria parasite Plasmodium falciparum are inserted into the membrane of infected red blood cells, where they mediate adhesion to a variety of human receptors. The DBL domains of the var2csa-encoded PfEMP1 protein play a critical role in malaria of pregnancy, tethering infected cells to the surface of the placenta through interactions with the glycosaminoglycan carbohydrate chondroitin sulfate A (CSA). A CSA-binding DBL domain has been overproduced in a bacterial expression system, purified and crystallized. Native data sets extending to 1.9 Å resolution have been collected and phasing is under way.

  13. The same-location cost is unrelated to attentional settings: an object-updating account.

    Science.gov (United States)

    Carmel, Tomer; Lamy, Dominique

    2014-08-01

    What mechanisms allow us to ignore salient yet irrelevant visual information has been a matter of intense debate. According to the contingent-capture hypothesis, such information is filtered out, whereas according to the salience-based account, it captures attention automatically. Several recent studies have reported a same-location cost that appears to fit neither of these accounts. These showed that responses may actually be slower when the target appears at the location just occupied by an irrelevant singleton distractor. Here, we investigated the mechanisms underlying this same-location cost. Our findings show that the same-location cost is unrelated to automatic attentional capture or strategic setting of attentional priorities, and therefore invalidate the feature-based inhibition and fast attentional disengagement accounts of this effect. In addition, we show that the cost is wiped out when the cue and target are not perceived as parts of the same object. We interpret these findings as indicating that the same-location cost has been previously misinterpreted by both bottom-up and top-down theories of attentional capture. We propose that it is better understood as a consequence of object updating, namely, as the cost of updating the information stored about an object when this object changes across time.

  14. Electromagnetic pulse (EMP) survey of the Idaho State Emergency Operating Center, Boise, Idaho

    Energy Technology Data Exchange (ETDEWEB)

    Crutcher, R.I.; Buchanan, M.E.; Jones, R.W.

    1992-02-01

    The purpose of this report is to develop an engineering design package to protect the Federal Emergency Management Agency (FEMA) National Radio System (FNARS) facilities from the effects of high- altitude electromagnetic pulses (HEMPs). This report was developed specifically for the Idaho State Emergency Operating Center (EOC) in Boise, Idaho. It is highly probable that there will be a heavy dependence upon high-frequency (hf) radio communications for long- haul communications following a nuclear attack on the continental United States, should one occur. To maintain the viability of the FEMA hf radio network during such a situation, steps must be taken to protect the FNARS facilities against the effects of HEMP that are likely to be created in a nuclear confrontation. The solution must than be to reduce HEMP-induced stresses on the system by means of tailored retrofit hardening measures using commercial protection devices when available. It is the intent of this report to define the particular hardening measures that will minimize the susceptibility of system components to HEMP effects. To the extent economically viable, protective actions have been recommended for implementation, along with necessary changes or additions, during the period of the FNARS upgrade program. This report addresses electromagnetic pulse (EMP) effects only and disregards any condition in which radiation effects may be a factor. It has been established that, except for the source region of a surface burst, EMP effects of high-altitude bursts are more severe than comparable detonations in either air or surface regions. Any system hardened to withstand the more extreme EMP environment will survive the less severe EMP conditions. The threatening environment will therefore be limited to HEMP situations.

  15. Role of Off-Line-of-Sight Propagation in Geomagnetic EMP Formation

    Energy Technology Data Exchange (ETDEWEB)

    Kruger, Hans W. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-05-23

    The author’s synchrotron radiation based 3D geomagnetic EMP code MACSYNC has been used to explore the impact on pulse rise time and air conductivity of EMP propagation paths to the observer that are located off the direct line-of-sight (LOS) between gamma source and observer. This geometry is always present because, for an isotropic source, most the gammas are emitted at an angle with respect to the LOS. Computations for a 1 kt near-surface burst observed from space yield two principal findings: 1. The rise time is generated by the combined actions of a) electron spreading along the LOS due to the Compton electron emission angular distribution folded with electron multiple scattering effects, and b) radiation arrival time spreading due to length differences for different off-LOS propagation paths. The pulse rise time does not depend on the rise time of the conductivity. The conductivity rise time determines the pulse amplitude. 2. One-dimensional legacy EMP codes are inherently incapable of producing the correct pulse shape because they cannot treat the dependence of the conductivity on two dimensions, i.e. the radius from the source and the angle of the propagation path with the LOS. This divergence from one-dimensionality begins at a small fraction of a nanosecond for a sea-level burst. This effect will also be present in high-altitude bursts, however, determination of its onset time and magnitude requires high-altitude computations which have not yet been done.

  16. 49 CFR 1002.3 - Updating user fees.

    Science.gov (United States)

    2010-10-01

    ... updating fees. Each fee shall be updated by updating the cost components comprising the fee. Cost... direct labor costs are direct labor costs determined by the cost study set forth in Revision of Fees For... by total office costs for the Offices directly associated with user fee activity. Actual updating of...

  17. Hardening techniques for nuclear generated EMPs: Pt. 1

    International Nuclear Information System (INIS)

    Anon.

    1987-01-01

    This article is intended as an introduction to the protection of electronic equipment against the effects of the electromagnetic pulse (EMP) generated by a nuclear explosion. For explosions at heights above 100 km the energy in the pulse is considerable over areas of many thousands of square metres. This constitutes a major threat to electronic equipments which have not been exposed to the consequences of closer nuclear explosions (namely blast, thermal and nuclear radiation)

  18. La depresión en la infancia desde la perspectiva de las taxonomías empíricas

    OpenAIRE

    López Soler, Concepción; López Pina, José Antonio

    1998-01-01

    En este trabajo se analiza la depresión infantil desde el modelo de taxonomías empíricas propuesto por Achenbach y Edelbrock. Se revisan algunos aspectos diferenciales en el diagnóstico de la depresión en menores y adultos. La parte empírica se cent

  19. Magnetohydrodynamic Electromagnetic Pulse (MHD-EMP) Interaction with Power Transmission and Distribution Systems

    National Research Council Canada - National Science Library

    Tesche, F. M; Barnes, P. R; Meliopoulos, A. P

    1992-01-01

    .... This environment, known as the magnetohydrodynamic electromagnetic pulse (MHD-EMP , is a very slowly varying electric field induced in the earth's surface, similar to the field induced by a geomagnetic storm...

  20. Parasites causing cerebral falciparum malaria bind multiple endothelial receptors and express EPCR and ICAM-1-binding PfEMP1

    DEFF Research Database (Denmark)

    Tuikue Ndam, Nicaise; Moussiliou, Azizath; Lavstsen, Thomas

    2017-01-01

    Background: Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) mediates the binding and accumulation of infected erythrocytes (IE) to blood vessels and tissues. Specific interactions have been described between PfEMP1 and human endothelial proteins CD36, intercellular adhesion molecule-1...

  1. Evasion of Immunity to Plasmodium falciparum: Rosettes of Blood Group A Impair Recognition of PfEMP1

    Science.gov (United States)

    Moll, Kirsten; Palmkvist, Mia; Ch'ng, Junhong; Kiwuwa, Mpungu Steven; Wahlgren, Mats

    2015-01-01

    The ABO blood group antigens are expressed on erythrocytes but also on endothelial cells, platelets and serum proteins. Notably, the ABO blood group of a malaria patient determines the development of the disease given that blood group O reduces the probability to succumb in severe malaria, compared to individuals of groups A, B or AB. P. falciparum rosetting and sequestration are mediated by PfEMP1, RIFIN and STEVOR, expressed at the surface of the parasitized red blood cell (pRBC). Antibodies to these antigens consequently modify the course of a malaria infection by preventing sequestration and promoting phagocytosis of pRBC. Here we have studied rosetting P. falciparum and present evidence of an immune evasion mechanism not previously recognized. We find the accessibility of antibodies to PfEMP1 at the surface of the pRBC to be reduced when P. falciparum forms rosettes in blood group A RBC, as compared to group O RBC. The pRBC surrounds itself with tightly bound normal RBC that makes PfEMP1 inaccessible to antibodies and clearance by the immune system. Accordingly, pRBC of in vitro cloned P. falciparum devoid of ABO blood group dependent rosetting were equally well detected by anti-PfEMP1 antibodies, independent of the blood group utilized for their propagation. The pathogenic mechanisms underlying the severe forms of malaria may in patients of blood group A depend on the ability of the parasite to mask PfEMP1 from antibody recognition, in so doing evading immune clearance. PMID:26714011

  2. FPGA-based Upgrade to RITS-6 Control System, Designed with EMP Considerations

    International Nuclear Information System (INIS)

    Anderson, Harold D.; Williams, John T.

    2009-01-01

    The existing control system for the RITS-6, a 20-MA 3-MV pulsed-power accelerator located at Sandia National Laboratories, was built as a system of analog switches because the operators needed to be close enough to the machine to hear pulsed-power breakdowns, yet the electromagnetic pulse (EMP) emitted would disable any processor-based solutions. The resulting system requires operators to activate and deactivate a series of 110-V relays manually in a complex order. The machine is sensitive to both the order of operation and the time taken between steps. A mistake in either case would cause a misfire and possible machine damage. Based on these constraints, a field-programmable gate array (FPGA) was chosen as the core of a proposed upgrade to the control system. An FPGA is a series of logic elements connected during programming. Based on their connections, the elements can mimic primitive logic elements, a process called synthesis. The circuit is static; all paths exist simultaneously and do not depend on a processor. This should make it less sensitive to EMP. By shielding it and using good electromagnetic interference-reduction practices, it should continue to operate well in the electrically noisy environment. The FPGA has two advantages over the existing system. In manual operation mode, the synthesized logic gates keep the operators in sequence. In addition, a clock signal and synthesized countdown circuit provides an automated sequence, with adjustable delays, for quickly executing the time-critical portions of charging and firing. The FPGA is modeled as a set of states, each state being a unique set of values for the output signals. The state is determined by the input signals, and in the automated segment by the value of the synthesized countdown timer, with the default mode placing the system in a safe configuration. Unlike a processor-based system, any system stimulus that results in an abort situation immediately executes a shutdown, with only a tens

  3. A review of mortality associated with elongate mineral particle (EMP) exposure in occupational epidemiology studies of gold, talc, and taconite mining.

    Science.gov (United States)

    Mandel, Jeffrey H; Alexander, Bruce H; Ramachandran, Gurumurthy

    2016-12-01

    Mining of gold, taconite, and talc may involve exposure to elongate mineral particles (EMP). The involved EMPs are typically non-asbestiform, include dimensions that regulatory definitions exclude, and have been less studied. A review of the literature was undertaken for this exposure and occupational epidemiological studies that occur in gold, talc, and taconite mining. Quantitative EMP exposure information in these industries is incomplete. However, there are consistent findings of pneumoconiosis in each of these types of mining. A recent case-control study suggests a possible association between this exposure and mesothelioma. Lung cancer is inconsistently reported in these industries and is an unlikely outcome of non-asbestiform EMP exposure. There is evidence of cardiovascular mortality excess across all of these types of mining. Non-malignant respiratory disease and cardiovascular mortality have been consistently increased in these industries. Further investigation, including additional insights for the role of non-asbestiform EMP, is warranted. Am. J. Ind. Med. 59:1047-1060, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  4. Evasion of immunity to Plasmodium falciparum malaria by IgM masking of protective IgG epitopes in infected erythrocyte surface-exposed PfEMP1

    DEFF Research Database (Denmark)

    Barfod, Lea; Dalgaard, Michael B; Pleman, Suzan T

    2011-01-01

    1 (PfEMP1) family is central to both. Here, we present evidence of a P. falciparum evasion mechanism not previously documented: the masking of PfEMP1-specific IgG epitopes by nonspecific IgM. Nonspecific IgM binding to erythrocytes infected by parasites expressing the PfEMP1 protein VAR2CSA...

  5. observaciones empíricas

    Directory of Open Access Journals (Sweden)

    Beatriz González Vázquez

    2007-01-01

    Full Text Available En el desarrollo y éxito de los espacios innovadores las relaciones entre los agentes integrantes de los mismos resultan esenciales. En este artículo se analizan las redes de relaciones en varias áreas tecnológicas, con el objetivo de comprobar si existe un mismo modelo en todas ellas. La red en dichos espacios se estudia tanto desde una perspectiva reticular, apoyándose en los atributos de las empresas y en las variables relacionales extraídas de los flujos entre las mismas, como desde la búsqueda de un modelo cuantitativo explicativo. El análisis empírico se realiza en las redes de tres Parques Tecnológicos, y de los resultados se extrae que la morfología de la red está influenciada por la estrategia de crecimiento que haya mantenido la dirección del parque en función de las condiciones industriales de su área geográfica. El análisis cuantitativo confirma el modelo centro-periferia observado en las redes.

  6. Experimental study on the EMP failure mode of DC solid state relay

    International Nuclear Information System (INIS)

    Sun Beiyun; Chen Xiangyue; Zhai Aibin; Mao Congguang

    2009-01-01

    DC solid state relay is a new type switch device without touch point, and is extensive used by aviation and spaceflight technique. In this paper, the EMP failure modes of solid state relays were obtained by current injection method. (authors)

  7. Concepts of incremental updating and versioning

    CSIR Research Space (South Africa)

    Cooper, Antony K

    2004-07-01

    Full Text Available of the work undertaken recently by the Working Group (WG). The WG was voted for a Commission by the General Assembly held at the 21st ICC in Durban, South Africa. The basic problem being addressed by the Commission is that a user compiles their data base... or election). Historically, updates have been provided in bulk, with the new data set replacing the old one. User could: ignore update (if it is not significant enough), manually (and selectively) update their data base, or accept the whole update...

  8. Hemiparesia esquerda consecutiva a empeçonhamento: Por Bothrops Jararacussu

    Directory of Open Access Journals (Sweden)

    Napoleão L. Teixeira

    1944-09-01

    Full Text Available O A. apresenta uma observação de hemiparesia esquerda, consecutiva a envenenamento por Bothrops Jararacussu. É o segundo caso que publica, com idêntica etiologia; além das suas, há duas outras observações semelhantes, de Octávio de Magalhães. Depois de discorrer sobre as hemiplegias cerebrais infantis - mais comuns - lembra que estas nem sempre se acompanham de espasticidade, podendo apresentar-se, raramente, com hipotonia muscular, ou mesmo de coréia, atetose, ou movimentos córeo-atetóticos que falam em favor de comprometimento extrapiramidal. Assinala, também, que crises epileptiformes - generalizadas ou parciais - podem ocorrer, o mesmo se podendo dizer de distúrbios psíquicos. Traduzir-se-iam, estes, por déficit intelectual marcado, podendo ir desde a debilidade mental até a idiotia; ou então, mesmo quando não há aparente comprometimento da esfera intelectual, por perturbações da afetividade, da vontade e do pragmatismo. Passando em revista as causas mais frequentes das hemiplegias cerebrais infantis, abre lugar, dentre elas, para os empeçonhamentos ofídico e escorpiônico (Magalhães e Guimarães. Estuda, a seguir, a patogenia das hemiplegias no decurso dos referidos empeçonhamentos, alinhando as hipóteses correntes, da preferência de conceituadas autoridades no assunto. Transcreve, finalmente, sua observação clínica, da qual se pode concluir, sem dúvida possível, haver, no caso "que apresenta, estreita e imediata ligação entre o envenenamento ofídico e a hemiparesia em estudo. O observado seria portador, além do mais, de crises epileptiformes generalizadas, aparecidas logo a seguir ao empeçonhamento. Além da fotografia do caso que apresenta, mostra-nos o A. outra, de caso anteriormente publicado, este, porém, de hemiplegia cerebral infantil típica, instalada aos 11 anos, após picada de Bothrops jararaca.

  9. Contra um Fetichismo nos Estudos Empíricos em Direito Internacional: Moldura Intencional e o Esvaziamento Significativo da Empiria

    Directory of Open Access Journals (Sweden)

    Artur Roberto Capella Giannattasio

    2018-04-01

    Full Text Available Os estudos em Direito Internacional no Brasil têm se aproximado de uma tendência neo-realista do Direito, a qual visa a usar técnicas empíricas na construção e na apresentação de seu objeto para verificar as condições materiais de criação e aplicação do Direito Internacional. Apesar da relevância dessa abordagem para aprimorar o conhecimento jurídico-científico internacional, este trabalho suscita um alerta fenomenológico de matriz husserliana. A discussão recente em torno da criação de uma Corte Constitucional Internacional (CCI se mostra um exemplo ilustrativo. A partir de análise qualitativa documental de fontes primárias e secundárias relativas à CCI, este estudo ressalta que um mesmo material empírico pode sustentar argumentos divergentes - no caso, reforço ou mitigação da autodeterminação dos povos. Essa divergência é interpretada epistemologicamente de acordo com o pensamento fenomenológico husserliano. Percebe-se que, independentemente do material empírico coletado, as conclusões se estabelecem de acordo com o posicionamento categorial do pesquisador. Argumenta-se assim que, apesar de haver uma aderência ao significante empírico, o processo de significação pouco depende dele, o qual tem seu sentido esvaziado. Por isso, argumenta-se que a busca de explicações sobre a origem e a efetividade do Direito Internacional não se restringe a uma dimensão estritamente empírica: apesar de ser necessário incorporar e aprimorar técnicas empíricas nos estudos em Direito Internacional, os limites de aplicação e de eficácia de suas normas jurídicas também derivam de condições imateriais vinculadas às restrições significativas relativas à posição categorial daqueles que as estudam e as operacionalizam.

  10. DEVELOPING LINGUISTIC SKILLS AND ABILITIES IN EMP STUDENTS

    Directory of Open Access Journals (Sweden)

    Nataša Milosavljević

    2012-03-01

    Full Text Available English for medical purposes falls within the category of discipline-specific language learning. It is characterized by specific linguistic features and requires specific study that is possible to carry out using specially designed programmes. Reading skill is one way of learning strategy of English for medical purposes. Most often, students use this skill in order to obtain information for some particular topic from the area of medical science, or because they need some sort of instruction in order to carry out certain task. Vocabulary acquisition plays a very important role in EMP teaching. It is achieved best through learning vocabulary in context, rather than in isolation. One of the most important questions in EMP teaching is related to what grammatical constructions should be analysed and emphasised. Some types of these activities would include, for example, asking students to find examples of one particular structure in the text or fill in the blanks with the missing forms such as tenses, passive forms, prepositions, etc. Speaking skill represents productive skill the aim of which is communication. In order for foreign language communication to be suucessful, a student should know linguistic and cultural features of native speakers and follow certain rules and conventions that are not easy to define. It is of crucial importance that during teaching process students develop strategies and techniques that will help them use linguistic structures fluently, apply language in different situations, take part in discussions, and use acquired vocabulary in accurate and precise way.

  11. Ontology-based geographic data set integration

    NARCIS (Netherlands)

    Uitermark, H.T.J.A.; Uitermark, Harry T.; Oosterom, Peter J.M.; Mars, Nicolaas; Molenaar, Martien; Molenaar, M.

    1999-01-01

    In order to develop a system to propagate updates we investigate the semantic and spatial relationships between independently produced geographic data sets of the same region (data set integration). The goal of this system is to reduce operator intervention in update operations between corresponding

  12. Dissection of the role of PfEMP1 and ICAM-1 in the sensing of Plasmodium-falciparum-infected erythrocytes by natural killer cells.

    Directory of Open Access Journals (Sweden)

    Myriam Baratin

    Full Text Available BACKGROUND: Host innate immunity contributes to malaria clinical outcome by providing protective inflammatory cytokines such as interferon-gamma, and by shaping the adaptive immune response. Plasmodium falciparum (Pf is the etiologic agent of the most severe forms of human malaria. Natural Killer (NK cells are lymphocytes of the innate immune system that are the first effectors to produce interferon-gamma in response to Pf. However, the molecular bases of Pf-NK cell recognition events are unknown. Our study focuses on the role of Pf erythrocyte membrane protein 1 (PfEMP1, a major Pf virulence factor. PfEMP1 is expressed on parasitized-erythrocytes and participates to vascular obstruction through the binding to several host receptors. PfEMP1 is also a pivotal target for host antibody response to Pf infection. METHODOLOGY/PRINCIPAL FINDINGS: Using genetically-engineered parasite mutant strains, a human genetic deficiency, and blocking antibodies, we identified two receptor-ligand pairs involved in two uncoupled events occurring during the sensing of Pf infection by NK cells. First, PfEMP1 interaction with one of its host receptor, chondroitin sulfate A, mediates the cytoadhesion of Pf-infected erythrocytes to human NK cell lines, but is not required for primary NK cell activation. Second, intercellular adhesion molecule-1 (ICAM-1, another host receptor for PfEMP1, is mandatory for NK cell interferon-gamma response. In this case, ICAM-1 acts via its engagement with its host ligand, LFA-1, and not with PfEMP1, consistent with the obligatory cross-talk of NK cells with macrophages for their production of interferon-gamma. CONCLUSION/SIGNIFICANCE: PfEMP1-independent but ICAM-1/LFA-1-dependent events occurring during NK cell activation by Pf highlight the fundamental role of cellular cooperation during innate immune response to malaria.

  13. A semi-automated multiplex high-throughput assay for measuring IgG antibodies against Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) domains in small volumes of plasma

    DEFF Research Database (Denmark)

    Cham, Gerald K K; Kurtis, Jonathan; Lusingu, John

    2008-01-01

    -based assay was sensitive, accurate and reproducible. Four recombinant PfEMP1 proteins C17, D5, D9 and D12, selected on the basis that they showed a spread of median fluorescent intensity (MFI) values from low to high when analysed by the bead-based assay were analysed by ELISA and the results from both...... reactivity levels to twenty eight different recombinant PfEMP1 proteins were simultaneously measured using a single microliter of plasma. Thus, the assay reported here provides a useful tool for rapid and efficient quantification of antibody reactivity against PfEMP1 variants in human plasma....... of twenty nine PfEMP1 domains were PCR amplified from 3D7 genomic DNA, expressed in the Baculovirus system and purified by metal-affinity chromatography. The antibody reactivity level to the recombinant PfEMP1 proteins in human hyper-immune plasma was measured by ELISA. In parallel, these recombinant PfEMP1...

  14. Mapping the transcription start points of the Staphylococcus aureus eap, emp, and vwb promoters reveals a conserved octanucleotide sequence that is essential for expression of these genes.

    Science.gov (United States)

    Harraghy, Niamh; Homerova, Dagmar; Herrmann, Mathias; Kormanec, Jan

    2008-01-01

    Mapping the transcription start points of the eap, emp, and vwb promoters revealed a conserved octanucleotide sequence (COS). Deleting this sequence abolished the expression of eap, emp, and vwb. However, electrophoretic mobility shift assays gave no evidence that this sequence was a binding site for SarA or SaeR, known regulators of eap and emp.

  15. Update of CERN exchange network

    CERN Multimedia

    2003-01-01

    An update of the CERN exchange network will be done next April. Disturbances or even interruptions of telephony services may occur from 4th to 24th April during evenings from 18:30 to 00:00 but will not exceed more than 4 consecutive hours (see tentative planning below). CERN divisions are invited to avoid any change requests (set-ups, move or removals) of telephones and fax machines from 4th to 25th April. Everything will be done to minimize potential inconveniences which may occur during this update. There will be no loss of telephone functionalities. CERN GSM portable phones won't be affected by this change. Should you need more details, please send us your questions by email to Standard.Telephone@cern.ch. DateChange typeAffected areas April 11 Update of switch in LHC 4 LHC 4 Point April 14 Update of switch in LHC 5 LHC 5 Point April 15 Update of switches in LHC 3 and LHC 2 Points LHC 3 and LHC 2 April 22 Update of switch N4 Meyrin Ouest April 23 Update of switch  N6 Prévessin Site Ap...

  16. Key Update Assistant for Resource-Constrained Networks

    DEFF Research Database (Denmark)

    Yuksel, Ender; Nielson, Hanne Riis; Nielson, Flemming

    2012-01-01

    developed a push-button solution - powered by stochastic model checking - that network designers can easily benefit from, and it paves the way for consumers to set up key update related security parameters. Key Update Assistant, as we named it, runs necessary model checking operations and determines...

  17. Implicaciones teóricas y empíricas de la nueva definición de desempleo en Colombia.

    OpenAIRE

    Guataquí, Juan; Taborda, Rodrigo

    2005-01-01

    En junio de 2000 Colombia adoptó una nueva definición de desempleo siguiendo los estándares de la OIT. Este cambio implicó una reducción de la tasa de desempleo del orden de dos puntos porcentuales. En este documento contrastamos el caso Colombiano con las experiencias de otros países en términos de la transformación metodológica y sus implicaciones empíricas. Posteriormente, evaluamos el soporte empírico del cambio de metodología. Nuestros resultados sugieren implicaciones esp...

  18. Implementing network constraints in the EMPS model

    Energy Technology Data Exchange (ETDEWEB)

    Helseth, Arild; Warland, Geir; Mo, Birger; Fosso, Olav B.

    2010-02-15

    This report concerns the coupling of detailed market and network models for long-term hydro-thermal scheduling. Currently, the EPF model (Samlast) is the only tool available for this task for actors in the Nordic market. A new prototype for solving the coupled market and network problem has been developed. The prototype is based on the EMPS model (Samkjoeringsmodellen). Results from the market model are distributed to a detailed network model, where a DC load flow detects if there are overloads on monitored lines or intersections. In case of overloads, network constraints are generated and added to the market problem. Theoretical and implementation details for the new prototype are elaborated in this report. The performance of the prototype is tested against the EPF model on a 20-area Nordic dataset. (Author)

  19. α2-macroglobulin can crosslink multiple Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) molecules and may facilitate adhesion of parasitized erythrocytes

    DEFF Research Database (Denmark)

    Stevenson, Liz; Laursen, Erik; Cowan, Graeme J

    2015-01-01

    -macroglobulin (α2M), which is both required and sufficient for rosetting mediated by the PfEMP1 protein HB3VAR06 and some other rosette-mediating PfEMP1 proteins. We map the α2M binding site to the C terminal end of HB3VAR06, and demonstrate that α2M can bind at least four HB3VAR06 proteins, plausibly....... Together, our results are evidence that P. falciparum parasites exploit α2M (and IgM) to expand the repertoire of host receptors available for PfEMP1-mediated IE adhesion, such as the erythrocyte carbohydrate moieties that lead to formation of rosettes. It is likely that this mechanism also affects IE...

  20. El enfoque empírico-inductivo y los problemas de la investigación social en Venezuela

    Directory of Open Access Journals (Sweden)

    Sorayda Rincón

    2001-05-01

    Full Text Available El hombre históricamente ha estudiado el conocimiento humano, buscando diferenciar el conocimiento vulgar del conocimiento científico. Existen diversas formas de producir el conocimiento científico que comienzan a formalizarse antes del siglo XX y en el siglo XX. En el siglo XX uno de los enfoques más importantes para la producción de conocimiento fue el enfoque empírico inductivo (positivismo que aún hoy día tiene gran influencia en las ciencias sociales en Venezuela. Es por ello, que la presente investigación tiene como propósito disertar de manera teórica acerca del enfoque empírico inductivo, su influencia y limitaciones en la producción del conocimiento científico en las ciencias sociales; así como, conocer y describir la opinión de los profesores universitarios sobre el mismo y su utilidad en las asesorías de tesis de pre-grado y postgrado. Para lograr este último objetivo, se utilizó un sondeo de opinión a los profesores universitarios sobre los criterios fundamentales del enfoque empírico inductivo, a saber: criterio de demarcación, inducción probabilística, lenguaje lógico y unificación de la ciencia. Los datos obtenidos del sondeo de opinión se tabularon a través de estadística descriptiva, con análisis de frecuencia. Obteniendo como conclusión que este enfoque es aún utilizado por muchos investigadores en el área de lo social, que a pesar que en el discurso muchos niegan su uso, en las asesorías de tesis lo promueven, orientando las mismas hacia un referente empírico y generalizando a partir de probabilidades y estadísticas

  1. Relaciones Empíricas Entre Empresas y Bancos. Una Visión Financiera Relaciones Empíricas Entre Empresas y Bancos. Una Visión Financiera

    Directory of Open Access Journals (Sweden)

    Andrea Escobar Grisales

    2003-12-01

    Full Text Available The research group on economics and business carried out the project "theoretical and empiricalaspects of firms – banks" relationship. The general objective was developing an investigationabout the channels and variables through which a relationship is establish between firms returnand performance, on one hand, and banks´ solvency and returns´ on the other.The main purpose of this paper is discussing the importance of firms´ financial management onfinancial sector credit policy establishment.El Grupo de Estudios en Economía y Empresa desarrolló, durante 2003, el proyecto Aspectosteóricos y empíricos de la relación empresas-bancos, cuyo objetivo general fue realizar una indagación sobre los canales y las variables a través de los cuales se establece una relación entre la rentabilidad y desempeño de las empresas, con la solidez y rentabilidad de los bancos (con datos de la economía colombiana para el lapso 1995-2000: para ello, se realizaron dos ejercicios, uno de carácter estadístico y otro de análisis financiero. El propósito de este artículo es presentar, en detalle, el análisis financiero de las relaciones empíricas entre bancos y empresas del sector real.

  2. EMP Attachment 3 DOE-SC PNNL Site Dose Assessment Guidance

    Energy Technology Data Exchange (ETDEWEB)

    Snyder, Sandra F.

    2011-12-21

    This Dose Assessment Guidance (DAG) describes methods to use to determine the Maximally-Exposed Individual (MEI) location and to estimate dose impact to that individual under the U.S. Department of Energy Office of Science (DOE-SC) Pacific Northwest National Laboratory (PNNL) Site Environmental Monitoring Plan (EMP). This guidance applies to public dose from radioactive material releases to the air from PNNL Site operations. This document is an attachment to the Pacific Northwest National Laboratory (PNNL) Environmental Monitoring Plan (EMP) and describes dose assessment guidance for radiological air emissions. The impact of radiological air emissions from the U.S. Department of Energy Office of Science (DOE-SC) PNNL Site is indicated by dose estimates to a maximally exposed member of the public, referred to as the maximally exposed individual (MEI). Reporting requirements associated with dose to members of the public from radiological air emissions are in 40 CFR Part 61.94, WAC 246-247-080, and DOE Order 458.1. The DOE Order and state standards for dose from radioactive air emissions are consistent with U.S. Environmental Protection Agency (EPA) dose standards in 40 CFR 61.92 (i.e., 10 mrem/yr to a MEI). Despite the fact that the current Contract Requirements Document (CRD) for the DOE-SC PNNL Site operations does not include the requirement to meet DOE CRD 458.1, paragraph 2.b, public dose limits, the DOE dose limits would be met when EPA limits are met.

  3. ACE-FTS version 3.0 data set: validation and data processing update

    Directory of Open Access Journals (Sweden)

    Claire Waymark

    2014-01-01

    Full Text Available On 12 August 2003, the Canadian-led Atmospheric Chemistry Experiment (ACE was launched into a 74° inclination orbit at 650 km with the mission objective to measure atmospheric composition using infrared and UV-visible spectroscopy (Bernath et al. 2005. The ACE mission consists of two main instruments, ACE-FTS and MAESTRO (McElroy et al. 2007, which are being used to investigate the chemistry and dynamics of the Earth’s atmosphere.  Here, we focus on the high resolution (0.02 cm-1 infrared Fourier Transform Spectrometer, ACE-FTS, that measures in the 750-4400 cm-1 (2.2 to 13.3 µm spectral region.  This instrument has been making regular solar occultation observations for more than nine years.  The current ACE-FTS data version (version 3.0 provides profiles of temperature and volume mixing ratios (VMRs of more than 30 atmospheric trace gas species, as well as 20 subsidiary isotopologues of the most abundant trace atmospheric constituents over a latitude range of ~85°N to ~85°S.  This letter describes the current data version and recent validation comparisons and provides a description of our planned updates for the ACE-FTS data set. [...

  4. A specific PfEMP1 is expressed in P. falciparum sporozoites and plays a role in hepatocyte infection

    DEFF Research Database (Denmark)

    Zanghì, Gigliola; Vembar, Shruthi S; Baumgarten, Sebastian

    2018-01-01

    Heterochromatin plays a central role in the process of immune evasion, pathogenesis, and transmission of the malaria parasite Plasmodium falciparum during blood stage infection. Here, we use ChIP sequencing to demonstrate that sporozoites from mosquito salivary glands expand heterochromatin......_SpzPfEMP1. Overall, we show that the epigenetic signature of var genes is reset in mosquito stages. Moreover, the identification of a strain-specific sporozoite PfEMP1 is highly relevant for vaccine design based on sporozoites....

  5. La relación entre creatividad y expertise: contribuciones teóricas y empíricas

    Directory of Open Access Journals (Sweden)

    Afonso C. T. Galvao

    2009-06-01

    Full Text Available La creatividad y el expertise son temas que están recibiendo mayor atención de los inves­tigadores en distintos campos del conocimiento. Atributos personales asociados a la alta producción creativa, factores que favorecen el desarrollo, la expresión de la creatividad y el expertise, así como los procesos implicados en el desarrollo de la alta competencia y la creatividad, son temas que han sido objeto de numerosos estudios. El presente estudio pre­senta contribuciones teóricas y estudios empíricos acerca de la creatividad y el expertise. Se describen los elementos comunes para el desarrollo de la creatividad y el expertise, así como las características de los ambientes educativos que los promueven, los modelos teóricos y estudios empíricos.

  6. Surface co-expression of two different PfEMP1 antigens on single Plasmodium falciparum-infected erythrocytes facilitates binding to ICAM1 and PECAM1

    DEFF Research Database (Denmark)

    Joergensen, Louise; Bengtsson, Dominique C; Bengtsson, Anja

    2010-01-01

    The Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) antigens play a major role in cytoadhesion of infected erythrocytes (IE), antigenic variation, and immunity to malaria. The current consensus on control of variant surface antigen expression is that only one PfEMP1 encoded by one var...

  7. Updating risk prediction tools: a case study in prostate cancer.

    Science.gov (United States)

    Ankerst, Donna P; Koniarski, Tim; Liang, Yuanyuan; Leach, Robin J; Feng, Ziding; Sanda, Martin G; Partin, Alan W; Chan, Daniel W; Kagan, Jacob; Sokoll, Lori; Wei, John T; Thompson, Ian M

    2012-01-01

    Online risk prediction tools for common cancers are now easily accessible and widely used by patients and doctors for informed decision-making concerning screening and diagnosis. A practical problem is as cancer research moves forward and new biomarkers and risk factors are discovered, there is a need to update the risk algorithms to include them. Typically, the new markers and risk factors cannot be retrospectively measured on the same study participants used to develop the original prediction tool, necessitating the merging of a separate study of different participants, which may be much smaller in sample size and of a different design. Validation of the updated tool on a third independent data set is warranted before the updated tool can go online. This article reports on the application of Bayes rule for updating risk prediction tools to include a set of biomarkers measured in an external study to the original study used to develop the risk prediction tool. The procedure is illustrated in the context of updating the online Prostate Cancer Prevention Trial Risk Calculator to incorporate the new markers %freePSA and [-2]proPSA measured on an external case-control study performed in Texas, U.S.. Recent state-of-the art methods in validation of risk prediction tools and evaluation of the improvement of updated to original tools are implemented using an external validation set provided by the U.S. Early Detection Research Network. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. La geografía como disciplina integral: notas teóricas y empíricas

    Directory of Open Access Journals (Sweden)

    Mauricio Herrera Rodríguez

    2010-01-01

    Full Text Available Este artículo responde al llamado a trascender las divisiones tradicionales entre Ciencias Sociales, Naturales y Humanidades y subraya cómo la Geografía ha internalizado muchos de los más recientes aportes teóricos y empíricos elaborados desde estas áreas, en un esfuerzo transdisciplinario por entender mejor la realidad socioambiental. Para darle coherencia teórica y relevancia práctica a este sincretismo intelectual, se propone un marco conceptual no reduccionista, elaborado por el geógrafo humanista Robert D. Sack (1997, 2003, 2010. Con el objetivo de ilustrar su pertinencia empírica, se discuten algunos paralelismos entre sus postulados y los propuestos por la "Evaluación de los ecosistemas del milenio" (2003 y por varios intelectuales destacados. Finalmente, se señala su potencial para responder constructivamente tanto al avasallador triunfalismo del mercado, como al relativismo desorientador y paralizante que con frecuencia domina nuestras discusiones públicas e intelectuales.

  9. Updates to the Demographic and Spatial Allocation Models to ...

    Science.gov (United States)

    EPA announced the availability of the draft report, Updates to the Demographic and Spatial Allocation Models to Produce Integrated Climate and Land Use Scenarios (ICLUS) for a 30-day public comment period. The ICLUS version 2 (v2) modeling tool furthered land change modeling by providing nationwide housing development scenarios up to 2100. ICLUS V2 includes updated population and land use data sets and addressing limitations identified in ICLUS v1 in both the migration and spatial allocation models. The companion user guide describes the development of ICLUS v2 and the updates that were made to the original data sets and the demographic and spatial allocation models. [2017 UPDATE] Get the latest version of ICLUS and stay up-to-date by signing up to the ICLUS mailing list. The GIS tool enables users to run SERGoM with the population projections developed for the ICLUS project and allows users to modify the spatial allocation housing density across the landscape.

  10. Map updates in a dynamic Voronoi data structure

    DEFF Research Database (Denmark)

    Mioc, Darka; Antón Castro, Francesc/François; Gold, C. M.

    2006-01-01

    In this paper we are using local and sequential map updates in the Voronoi data structure, which allows us to automatically record each event and performed map updates within the system. These map updates are executed through map construction commands that are composed of atomic actions (geometric...... algorithms for addition, deletion, and motion of spatial objects) on the dynamic Voronoi data structure. The formalization of map commands led to the development of a spatial language comprising a set of atomic operations or constructs on spatial primitives (points and lines), powerful enough to define...

  11. Update of CERN exchange network

    CERN Multimedia

    2003-01-01

    An update of the CERN exchange network will be done next April. Disturbances or even interruptions of telephony services may occur from 4th to 24th April during evenings from 18:30 to 00:00 but will not exceed more than 4 consecutive hours (see tentative planning below). In addition, the voice messaging system will be shut down on March, 26th April from 18:00 to 00:00. Calls supposed to be routed to the voice messaging system will not be possible during the shutdown. CERN divisions are invited to avoid any change requests (set-ups, move or removals) of telephones and fax machines from 4th to 25th April. Everything will be done to minimize potential inconveniences which may occur during this update. There will be no loss of telephone functionalities. CERN GSM portable phones won't be affected by this change. Should you need more details, please send us your questions by email to Standard.Telephone@cern.ch. DateChange typeAffected areas March 26Update of the voice messaging systemAll CERN sites April 4Updat...

  12. PENGOLAHAN BUAH DAN BIJI RAMBUTAN SEBAGAI MAKANAN TRADISIONAL KOKTAIL, MANISAN, EMPING BIJI RAMBUTAN DAN OBAT HERBAL YANG BERKHASIAT

    Directory of Open Access Journals (Sweden)

    Nuni Widiarti

    2013-02-01

    Full Text Available Kegiatan pengabdian kepada masyarakat berupa penyuluhan Pengolahan Buah Dan Biji Rambutan Sebagai Makanan Tradisional Koktail, Manisan, Emping Biji Rambutan Dan Obat Herbal Yang Berkhasiat bertujuan untuk memberikan pengetahuan kepada masyarakat khususnya ibu-ibu PKK dukuh kanggan Desa Wringinputih terhadap manfaat rambutan, dan biji rambutan terhadap kesehatan beserta bagaimana meningkatkan nilai jual rambutan dan biji rambutan pada saat panen raya. Khalayak sasaran dalam pengabdian masyarakat ini adalah ibu-ibu rumah tangga di dukuh Kanggan Desa Wringinputih khususnya warga RT 01 dan 02 RW XIII yang berjumlah 20 orang. Metode yang dilakukan dalam pngabdian ini adalah penyuluhan dan demonstrasi pembuatan emping serta manisan buah rambutan. Manfaat yang diperoleh dari hasil pengabdian ini adalah masyarakat menjadi tahu manfaat dari daun hingga akar dan buah rambutan terhadap berbagai penyakit dan kecantikan.

  13. Update of CERN exchange network

    CERN Multimedia

    2003-01-01

    An update of the CERN exchange network will be done next April. Disturbances or even interruptions of telephony services may occur from 4th to 24th April during evenings from 18:30 to 00:00 but will not exceed more than 4 consecutive hours (see tentative planning below). In addition, the voice messaging system will be shut down on March, 26th April from 18:00 to 00:00. Calls supposed to be routed to the voice messaging system will not be possible during the shutdown. CERN divisions are invited to avoid any change requests (set-ups, move or removals) of telephones and fax machines from 4th to 25th April. Everything will be done to minimize potential inconveniences which may occur during this update. There will be no loss of telephone functionalities. CERN GSM portable phones won't be affected by this change. Should you need more details, please send us your questions by email to Standard.Telephone@cern.ch. Date Change type Affected areas April 8 Update of switch in LHC 7 LHC 7 Point April 9 Update of...

  14. The Application of GIS Viewshed Analysis to Roman Urban Studies: the Case-Study of Empúries, Spain

    Directory of Open Access Journals (Sweden)

    Alan E. Kaiser

    2003-05-01

    Full Text Available This article demonstrates the potential of applying GIS viewshed analysis to Roman urban studies. It examines the visual dynamics of the Roman city of Empúries, Spain, through an analysis of the visibility of, and view from, a temple and a domus within the city. The analysis proves that the two buildings in question would have had wide views of the Gulf of Roses to the east of the city, and could easily have been seen by people in boats in the Gulf, but they were virtually invisible from within the city and would certainly not have dominated the cityscape. The article concludes that the absence of the villa and temple from the intramural cityscape of Empúries cautions modern investigators of ancient cities against simply assuming that currently prominent ruins on hills or ridges were also highly visible from near as well as far in antiquity.

  15. Implicaciones teóricas y empíricas de la nueva definición de desempleo en Colombia.

    Directory of Open Access Journals (Sweden)

    Juan Carlos Guataqui

    2010-05-01

    Full Text Available En junio de 2000 Colombia adoptó una nueva definición de desempleo siguiendo los estándares de la OIT. Este cambio implicó una reducción de la tasa de desempleo del orden de dos puntos porcentuales. En este documento contrastamos el caso Colombiano con las experiencias de otros países en términos de la transformación metodológica y sus implicaciones empíricas. Posteriormente, evaluamos el soporte empírico del cambio de metodología. Nuestros resultados sugieren implicaciones específicas sobre el desempleo estructural y su relación con el perfil educativo de los desempleados; por lo tanto, cuestionan la aplicación práctica de la definición estándar de desempleo de la OIT al caso colombiano.

  16. Feasibility of Isolating Vulnerable Equipment of the Electric Power System from Sources of EMP

    Science.gov (United States)

    1978-03-01

    is reclosed after the fault is cleared, the reclosure will probably be successful since no permanent conducting path for current exists. However...successive EMP-induced faults may cause reclosing circuit breakers and reclosers to lock out. 2. Lock out of reclosers and reclosing circuit breakers...Most distribution lines are protected by some sort of device that recloses the line after a fault is cleared. All such devices have a common

  17. A general framework for updating belief distributions.

    Science.gov (United States)

    Bissiri, P G; Holmes, C C; Walker, S G

    2016-11-01

    We propose a framework for general Bayesian inference. We argue that a valid update of a prior belief distribution to a posterior can be made for parameters which are connected to observations through a loss function rather than the traditional likelihood function, which is recovered as a special case. Modern application areas make it increasingly challenging for Bayesians to attempt to model the true data-generating mechanism. For instance, when the object of interest is low dimensional, such as a mean or median, it is cumbersome to have to achieve this via a complete model for the whole data distribution. More importantly, there are settings where the parameter of interest does not directly index a family of density functions and thus the Bayesian approach to learning about such parameters is currently regarded as problematic. Our framework uses loss functions to connect information in the data to functionals of interest. The updating of beliefs then follows from a decision theoretic approach involving cumulative loss functions. Importantly, the procedure coincides with Bayesian updating when a true likelihood is known yet provides coherent subjective inference in much more general settings. Connections to other inference frameworks are highlighted.

  18. Report of the Commission to Assess the Threat to the United States from Electromagnetic Pulse (EMP) Attack: Critical National Infrastructures

    National Research Council Canada - National Science Library

    Foster, Jr., John S; Gjelde, Earl; Graham, William R; Hermann, Robert J; Kluepfel, Henry M; Lawson, Richard L; Soper, Gordon K; Wood, Lowell L; Woodard, Joan B

    2008-01-01

    ...) attack on our critical national infrastructures. An earlier report, Report of the Commission to Assess the Threat to the United States from Electromagnetic Pulse (EMP), Volume 1: Executive Report (2004...

  19. A Provenance Tracking Model for Data Updates

    Directory of Open Access Journals (Sweden)

    Gabriel Ciobanu

    2012-08-01

    Full Text Available For data-centric systems, provenance tracking is particularly important when the system is open and decentralised, such as the Web of Linked Data. In this paper, a concise but expressive calculus which models data updates is presented. The calculus is used to provide an operational semantics for a system where data and updates interact concurrently. The operational semantics of the calculus also tracks the provenance of data with respect to updates. This provides a new formal semantics extending provenance diagrams which takes into account the execution of processes in a concurrent setting. Moreover, a sound and complete model for the calculus based on ideals of series-parallel DAGs is provided. The notion of provenance introduced can be used as a subjective indicator of the quality of data in concurrent interacting systems.

  20. Contramedidas em segurança da informação e vulnerabilidade cibernética: evidência empírica de empresas brasileiras

    OpenAIRE

    Cortez, Igor Siqueira; Kubota, Luis Claudio

    2013-01-01

    Recentemente, uma série de ataques cibernéticos a empresas e governos no Brasil e no exterior tornou público o potencial impacto econômico desse tipo de atividade, do ponto de vista tanto privado quanto público. Existe extensa literatura econômica - teórica e empírica - que avalia os incentivos para que as empresas adotem ou não medidas de segurança da informação. No presente estudo foi desenvolvida uma avaliação empírica desse fenômeno no Brasil. Modelos logit e probit ordenado foram desenvo...

  1. Update of CERN exchange network

    CERN Multimedia

    2003-01-01

    An update of the CERN exchange network will be done next April. Disturbances or even interruptions of telephony services may occur from 4th to 24th April during evenings from 18:30 to 00:00 but will not exceed more than 4 consecutive hours (see tentative planning below). In addition, the voice messaging system will be shut down on March, 26th April from 18:00 to 00:00. Calls supposed to be routed to the voice messaging system will not be possible during the shutdown. CERN divisions are invited to avoid any change requests (set-ups, move or removals) of telephones and fax machines from 4th to 25th April. Everything will be done to minimize potential inconveniences which may occur during this update. There will be no loss of telephone functionalities. CERN GSM portable phones won't be affected by this change. Should you need more details, please send us your questions by email to Standard.Telephone@cern.ch. Date Change type Affected areas March 26 Update of the voice messaging system All CERN sites April...

  2. Updated Abraham solvation parameters for polychlorinated biphenyls

    NARCIS (Netherlands)

    van Noort, P.C.M.; Haftka, J.J.H.; Parsons, J.R.

    2010-01-01

    This study shows that the recently published polychlorinated biphenyl (PCB) Abraham solvation parameters predict PCB air−n-hexadecane and n-octanol−water partition coefficients very poorly, especially for highly ortho-chlorinated congeners. Therefore, an updated set of PCB solvation parameters was

  3. Updated Abraham solvation parameters for polychlorinated biphenyls

    NARCIS (Netherlands)

    Noort, van P.C.M.; Haftka, J.J.H.; Parsons, J.R.

    2010-01-01

    This study shows that the recently published polychlorinated biphenyl (PCB) Abraham solvation parameters predict PCB air-n-hexadecane and n-octanol-water partition coefficients very poorly, especially for highly ortho-chlorinated congeners. Therefore, an updated set of PCB solvation parameters was

  4. De-MA: a web Database for electron Microprobe Analyses to assist EMP lab manager and users

    Science.gov (United States)

    Allaz, J. M.

    2012-12-01

    Lab managers and users of electron microprobe (EMP) facilities require comprehensive, yet flexible documentation structures, as well as an efficient scheduling mechanism. A single on-line database system for managing reservations, and providing information on standards, quantitative and qualitative setups (element mapping, etc.), and X-ray data has been developed for this purpose. This system is particularly useful in multi-user facilities where experience ranges from beginners to the highly experienced. New users and occasional facility users will find these tools extremely useful in developing and maintaining high quality, reproducible, and efficient analyses. This user-friendly database is available through the web, and uses MySQL as a database and PHP/HTML as script language (dynamic website). The database includes several tables for standards information, X-ray lines, X-ray element mapping, PHA, element setups, and agenda. It is configurable for up to five different EMPs in a single lab, each of them having up to five spectrometers and as many diffraction crystals as required. The installation should be done on a web server supporting PHP/MySQL, although installation on a personal computer is possible using third-party freeware to create a local Apache server, and to enable PHP/MySQL. Since it is web-based, any user outside the EMP lab can access this database anytime through any web browser and on any operating system. The access can be secured using a general password protection (e.g. htaccess). The web interface consists of 6 main menus. (1) "Standards" lists standards defined in the database, and displays detailed information on each (e.g. material type, name, reference, comments, and analyses). Images such as EDS spectra or BSE can be associated with a standard. (2) "Analyses" lists typical setups to use for quantitative analyses, allows calculation of mineral composition based on a mineral formula, or calculation of mineral formula based on a fixed

  5. La tasa de crecimiento garantizada de Harrod como ley del crecimiento económico. Una comprobación empírica

    Directory of Open Access Journals (Sweden)

    Bernal Bellón José Reyes Reyes

    2008-12-01

    Full Text Available En teoría del crecimiento hubo desarrollos importantes en la década de los 50 a partir del modelo de crecimiento poskeynesiano de Harrod (1939, los cuales buscaban solucionar teóricamente el problema de inestabilidad que presentaba este modelo. No obstante, no se ha realizado una comprobación empírica literal del modelo. En el presente trabajo se modifica el modelo de Harrod incluyendo el cambio técnico y se realiza una comprobación
    empírica a través de diferentes metodologías. Se concluye que la tasa de crecimiento garantizada de Harrod tiende a ser una ley en teoría del crecimiento económico.

  6. State of the art of dynamic software updating in Java

    DEFF Research Database (Denmark)

    Gregersen, Allan Raundahl; Rasmussen, Michael; Jørgensen, Bo Nørregaard

    2014-01-01

    The dynamic software updating system JRebel from Zeroturnaround has proven to be an efficient mean to improve developer productivity, as it allows developers to change the code of their applications while developing and testing them. Hence, developers no longer have to go through the tedious cycle......! with JRebel. The successful integration of these two systems will set a new standard for dynamic software updating in Java....

  7. Efficient Multiplicative Updates for Support Vector Machines

    DEFF Research Database (Denmark)

    Potluru, Vamsi K.; Plis, Sergie N; Mørup, Morten

    2009-01-01

    (NMF) problem. This allows us to derive a novel multiplicative algorithm for solving hard and soft margin SVM. The algorithm follows as a natural extension of the updates for NMF and semi-NMF. No additional parameter setting, such as choosing learning rate, is required. Exploiting the connection......The dual formulation of the support vector machine (SVM) objective function is an instance of a nonnegative quadratic programming problem. We reformulate the SVM objective function as a matrix factorization problem which establishes a connection with the regularized nonnegative matrix factorization...... between SVM and NMF formulation, we show how NMF algorithms can be applied to the SVM problem. Multiplicative updates that we derive for SVM problem also represent novel updates for semi-NMF. Further this unified view yields algorithmic insights in both directions: we demonstrate that the Kernel Adatron...

  8. Updating Geospatial Data from Large Scale Data Sources

    Science.gov (United States)

    Zhao, R.; Chen, J.; Wang, D.; Shang, Y.; Wang, Z.; Li, X.; Ai, T.

    2011-08-01

    and non-technical factors, followed by the general strategy of digital map generalization in practical production environment. In fact the most important factor is recognized that it is very difficult to establish generalization rules for production systems. We emphasized on this factor in our work and established a set of rules or constrains for scale topographical database updating 1:50000 scaled data from 1:10000 scaled data in a full digital environment mainly based on map specifications. Finally, We discussed the generic system structure and give an example of production system used in the project of 1:50000 scaled database updating in China.

  9. Antigenic variation and the genetics and epigenetics of the PfEMP1 erythrocyte surface antigens in Plasmodium falciparum malaria

    DEFF Research Database (Denmark)

    Arnot, David E; Jensen, Anja T R

    2011-01-01

    . Sterile immunity is not achieved and chronic parasitization of apparently healthy adults is the norm. In this article, we analyse the best understood malaria "antigenic variation" system, that based on Plasmodium falciparum's PfEMP1-type cytoadhesion antigens, and critically review recent literature...

  10. Structure-guided identification of a family of dual receptor-binding PfEMP1 that is associated with cerebral malaria

    DEFF Research Database (Denmark)

    Lennartz, Frank; Adams, Yvonne; Bengtsson, Anja

    2017-01-01

    Cerebral malaria is a deadly outcome of infection by Plasmodium falciparum, occurring when parasite-infected erythrocytes accumulate in the brain. These erythrocytes display parasite proteins of the PfEMP1 family that bind various endothelial receptors. Despite the importance of cerebral malaria...

  11. 76 FR 68525 - Medicare Program; Home Health Prospective Payment System Rate Update for Calendar Year 2012

    Science.gov (United States)

    2011-11-04

    ... Prospective Payment System Rate Update for Calendar Year 2012; Final Rule #0;#0;Federal Register / Vol. 76, No... 0938-AQ30 Medicare Program; Home Health Prospective Payment System Rate Update for Calendar Year 2012... sets forth updates to the home health prospective payment system (HH PPS) rates, including: the...

  12. Antibody reactivity to conserved linear epitopes of Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1)

    DEFF Research Database (Denmark)

    Staalsø, T; Khalil, E A; Elhassan, I M

    1998-01-01

    recognising the conserved regions of PfEMP1 arise upon exposure to the parasite, and that these may be involved in the development of protection against malaria. Antibodies to the Pfalhesin peptide of the human aniontransporter, band3, were measured by the same method. The magnitude of this antibody response...

  13. Towards Dynamic Updates in Service Composition

    Directory of Open Access Journals (Sweden)

    Mario Bravetti

    2015-12-01

    Full Text Available We survey our results about verification of adaptable processes. We present adaptable processes as a way of overcoming the limitations that process calculi have for describing patterns of dynamic process evolution. Such patterns rely on direct ways of controlling the behavior and location of running processes, and so they are at the heart of the adaptation capabilities present in many modern concurrent systems. Adaptable processes have named scopes and are sensible to actions of dynamic update at runtime; this allows to express dynamic and static topologies of adaptable processes as well as different evolvability patterns for concurrent processes. We introduce a core calculus of adaptable processes and consider verification problems for them: first based on specific properties related to error occurrence, that we call bounded and eventual adaptation, and then by considering a simple yet expressive temporal logic over adaptable processes. We provide (undecidability results of such verification problems over adaptable processes considering the spectrum of topologies/evolvability patterns introduced. We then consider distributed adaptability, where a process can update part of a protocol by performing dynamic distributed updates over a set of protocol participants. Dynamic updates in this context are presented as an extension of our work on choreographies and behavioural contracts in multiparty interactions. We show how update mechanisms considered for adaptable processes can be used to extend the theory of choreography and orchestration/contracts, allowing them to be modified at run-time by internal (self-adaptation or external intervention.

  14. Self-regulation of frontal-midline theta facilitates memory updating and mental set shifting

    Directory of Open Access Journals (Sweden)

    Stefanie eEnriquez-Geppert

    2014-12-01

    Full Text Available Frontal-midline (fm theta oscillations as measured via the electroencephalogram (EEG have been suggested as neural working language of executive functioning. Their power has been shown to increase when cognitive processing or task performance is enhanced. Thus, the question arises whether learning to increase fm-theta amplitudes would functionally impact the behavioral performance in tasks probing executive functions (EFs. Here, the effects of neurofeedback, a learning method to self-up-regulate fm-theta over frontal-midline electrodes, on the four most representative EFs, memory updating, set shifting, conflict monitoring, and motor inhibition are presented. Before beginning and after completing an individualized, eight-session gap-spaced neurofeedback intervention, the three-back, letter/number task-switching, Stroop, and stop-signal tasks were tested while measuring the EEG. Self-determined up-regulation of fm-theta and its putative role for executive functioning were compared to an active control group, the so-called pseudo-neurofeedback group. Task-related fm-theta activity after training differed significantly between groups. More importantly, though, after neurofeedback significantly enhanced behavioral performance was observed. The training group showed higher accuracy scores in the three-back task and reduced mixing and shifting costs in letter/number task-switching. However, this specific protocol type did not affect performance in tasks probing conflict monitoring and motor inhibition. Thus, our results suggest a modulation of proactive but not reactive mechanisms of cognitive control. In sum, the modulation of fm-theta via neurofeedback may serve as potent treatment approach for executive dysfunctions.

  15. SAVY-4000 Field Surveillance Plan Update for 2017

    Energy Technology Data Exchange (ETDEWEB)

    Kelly, Elizabeth J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Stone, Timothy Amos [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Smith, Paul Herrick [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Reeves, Kirk Patrick [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Veirs, Douglas Kirk [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Prochnow, David Adrian [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-03-20

    The Packaging Surveillance Program section of the Department of Energy (DOE) Manual 441.1-­1, Nuclear Material Packaging Manual (DOE 2008), requires DOE contractors to “ensure that a surveillance program is established and implemented to ensure the nuclear material storage package continues to meet its design criteria.”This 2017 update reflects changes to the surveillance plan resulting from surveillance findings as documented in Reeves et al. 2016. These findings include observations of corrosion in SAVY and Hagan containers and the indication (in one SAVY container) of possible filter membrane thermal degradation. This surveillance plan update documents the rationale for selecting surveillance containers, specifies the containers for 2017 surveillance, and identifies a minimum set of containers for 2018 surveillance. This update contains important changes to the previous surveillance plans.

  16. Set-Membership Proportionate Affine Projection Algorithms

    Directory of Open Access Journals (Sweden)

    Stefan Werner

    2007-01-01

    Full Text Available Proportionate adaptive filters can improve the convergence speed for the identification of sparse systems as compared to their conventional counterparts. In this paper, the idea of proportionate adaptation is combined with the framework of set-membership filtering (SMF in an attempt to derive novel computationally efficient algorithms. The resulting algorithms attain an attractive faster converge for both situations of sparse and dispersive channels while decreasing the average computational complexity due to the data discerning feature of the SMF approach. In addition, we propose a rule that allows us to automatically adjust the number of past data pairs employed in the update. This leads to a set-membership proportionate affine projection algorithm (SM-PAPA having a variable data-reuse factor allowing a significant reduction in the overall complexity when compared with a fixed data-reuse factor. Reduced-complexity implementations of the proposed algorithms are also considered that reduce the dimensions of the matrix inversions involved in the update. Simulations show good results in terms of reduced number of updates, speed of convergence, and final mean-squared error.

  17. The effects of corona on current surges induced on conducting lines by EMP: A comparison of experiment data with results of analytic corona models

    Science.gov (United States)

    Blanchard, J. P.; Tesche, F. M.; McConnell, B. W.

    1987-09-01

    An experiment to determine the interaction of an intense electromagnetic pulse (EMP), such as that produced by a nuclear detonation above the Earth's atmosphere, was performed in March, 1986 at Kirtland Air Force Base near Albuquerque, New Mexico. The results of that experiment have been published without analysis. Following an introduction of the corona phenomenon, the reason for interest in it, and a review of the experiment, this paper discusses five different analytic corona models that may model corona formation on a conducting line subjected to EMP. The results predicted by these models are compared with measured data acquired during the experiment to determine the strengths and weaknesses of each model.

  18. Users Manual for TMY3 Data Sets (Revised)

    Energy Technology Data Exchange (ETDEWEB)

    Wilcox, S.; Marion, W.

    2008-05-01

    This users manual describes how to obtain and interpret the data in the Typical Meteorological Year version 3 (TMY3) data sets. These data sets are an update to the TMY2 data released by NREL in 1994.

  19. [The Danish Debate on Priority Setting in Medicine--An Update].

    Science.gov (United States)

    Pornak, S C; Raspe, H

    2015-09-01

    In the last years, the Danish debate about priority setting in medicine has gained new strength. This paper shows the main focuses of the current discussion based on a research of Danish primary literature. For the first time since the 1990s the Danish Council of Ethics has been involved with priority setting in medicine in a project running from 2011 to 2013. The Council emphasises the importance of legitimate processes and calls for visible values and criteria. A focus of the debate is how to deal with new expensive drugs. Politicians, physicians, health economists and the Council of Ethics have called for a national institution for priority setting in medicine. They have mainly looked to the Norwegian National Council for Priority Setting in Health Care and the British National Institute for Health and Care Excellence for inspiration. The Danish Government considered establishing a national institute for priority setting, but the plans were not put into practice. In the year 2012 a new national project was launched to create clinical guidelines. Danish doctors welcome the guidelines as a good basis for priority setting. Just like in earlier Danish priority setting debates, a coordinating institution is lacking to bundle the discussion and keep it going. The debate seems to have come to an end once again. The fact that it was seriously considered to establish an institute for priority setting is a new development. It can be expected that the discussion will be resumed in the near future, possibly the idea of an institute for priority setting will be readopted. The general conditions for priority setting in health care have improved. © Georg Thieme Verlag KG Stuttgart · New York.

  20. Cultura intraemprendedora e innovación: un estudio empírico en las MIPYME turísticas colombianas

    Directory of Open Access Journals (Sweden)

    Edgar J. Gálvez Albarracín

    2011-12-01

    Full Text Available El objeto de este trabajo es verificar empíricamente la relación existente entre la cultura de intraemprendimiento y la innovación en las empresas. Para ello se realizó un estudio empírico con 68 MIPYME** del sector turístico de Colombia. Los resultados muestran que las prácticas asociadas al intraemprendimiento ejercen influencia positiva sobre la innovación de las MIPYME, y en especial, sobre la de sus procesos productivos y su gestión. Los hallazgos tienen implicaciones para los empresarios ya que les permite comprobar la utilidad del emprendimiento corporativo para el desarrollo de sus organizaciones. Muestra además al sector público, la academia y a las entidades de fomento, la importancia de impulsar programas de investigación, formación y asesoría en el campo del intraemprendimiento, para lograr mayor innovación y competitividad empresarial, lo cual puede redundar a su vez en mayor desarrollo regional y nacional

  1. Structural Conservation Despite Huge Sequence Diversity Allows EPCR Binding by the PfEMP1 Family Implicated in Severe Childhood Malaria

    DEFF Research Database (Denmark)

    Lau, Clinton K.Y.; Turner, Louise; Jespersen, Jakob S.

    2015-01-01

    with severe childhood malaria. We combine crystal structures of CIDRa1:EPCR complexes with analysis of 885 CIDRa1 sequences, showing that the EPCR-binding surfaces of CIDRa1 domains are conserved in shape and bonding potential, despite dramatic sequence diversity. Additionally, these domains mimic features...... of the natural EPCR ligand and can block this ligand interaction. Using peptides corresponding to the EPCR-binding region, antibodies can be purified from individuals in malaria-endemic regions that block EPCR binding of diverse CIDRa1 variants. This highlights the extent to which such a surface protein family......The PfEMP1 family of surface proteins is central for Plasmodium falciparum virulence and must retain the ability to bind to host receptors while also diversifying to aid immune evasion. The interaction between CIDRa1 domains of PfEMP1 and endothelial protein C receptor (EPCR) is associated...

  2. La PYME innovadora mexicana ante la crisis económica. Un estudio empírico

    OpenAIRE

    Edwin Estrella Pacheco; Gabriel Góngora Biachi; Marlene Martín Méndez

    2011-01-01

    Este trabajo estudia el crecimiento y el empleo de las empresas industriales manufactureras que son innovadoras del estado de Yucatán, en México, durante 2007-2009, periodo de la crisis financiera global. El incremento del desempleo es consecuencia del cierre de empresas, para recortar gastos. Se estudia el impacto de dicha crisis comparando el efecto en aquellas empresas que son innovadoras, con aquellas que no lo son. Se realiza un estudio empírico a 138 PYME, usando una entrevista dirigida...

  3. PhysarumSoft: An update based on rough set theory

    Science.gov (United States)

    Schumann, Andrew; Pancerz, Krzysztof

    2017-07-01

    PhysarumSoft is a software tool consisting of two modules developed for programming Physarum machines and simulating Physarum games, respectively. The paper briefly discusses what has been added since the last version released in 2015. New elements in both modules are based on rough set theory. Rough sets are used to model behaviour of Physarum machines and to describe strategy games.

  4. Finite element modelling and updating of friction stir welding (FSW joint for vibration analysis

    Directory of Open Access Journals (Sweden)

    Zahari Siti Norazila

    2017-01-01

    Full Text Available Friction stir welding of aluminium alloys widely used in automotive and aerospace application due to its advanced and lightweight properties. The behaviour of FSW joints plays a significant role in the dynamic characteristic of the structure due to its complexities and uncertainties therefore the representation of an accurate finite element model of these joints become a research issue. In this paper, various finite elements (FE modelling technique for prediction of dynamic properties of sheet metal jointed by friction stir welding will be presented. Firstly, nine set of flat plate with different series of aluminium alloy; AA7075 and AA6061 joined by FSW are used. Nine set of specimen was fabricated using various types of welding parameters. In order to find the most optimum set of FSW plate, the finite element model using equivalence technique was developed and the model validated using experimental modal analysis (EMA on nine set of specimen and finite element analysis (FEA. Three types of modelling were engaged in this study; rigid body element Type 2 (RBE2, bar element (CBAR and spot weld element connector (CWELD. CBAR element was chosen to represent weld model for FSW joints due to its accurate prediction of mode shapes and contains an updating parameter for weld modelling compare to other weld modelling. Model updating was performed to improve correlation between EMA and FEA and before proceeds to updating, sensitivity analysis was done to select the most sensitive updating parameter. After perform model updating, total error of the natural frequencies for CBAR model is improved significantly. Therefore, CBAR element was selected as the most reliable element in FE to represent FSW weld joint.

  5. Condições de trabalho do jornalista: o que revela a pesquisa empírica

    Directory of Open Access Journals (Sweden)

    Juliana Bulhões Alberto Dantas

    2017-03-01

    Full Text Available Investigamos acerca do impacto das condições de trabalho do jornalista na saúde e na qualidade de vida deste profissional. Apresentamos aqui um relato com os primeiros resultados da pesquisa, a partir de uma síntese das três etapas de desenvolvimento do trabalho: pesquisa exploratória, pesquisa bibliográfica e pesquisa de campo. Enfatizamos os resultados colhidos no pré-teste do instrumento e o levantamento de dados empíricos obtidos a partir de entrevistas em profundidade.

  6. Mapping the binding site of a cross-reactive Plasmodium falciparum PfEMP1 monoclonal antibody inhibitory of ICAM-1 binding

    DEFF Research Database (Denmark)

    Lennartz, Frank; Bengtsson, Anja; Olsen, Rebecca W

    2015-01-01

    The virulence of Plasmodium falciparum is linked to the ability of infected erythrocytes (IE) to adhere to the vascular endothelium, mediated by P. falciparum erythrocyte membrane protein 1 (PfEMP1). In this article, we report the functional characterization of an mAb that recognizes a panel of P...

  7. Inadimplência no Brasil: Uma Análise das Evidências Empíricas

    OpenAIRE

    Mariane Daros; Nelson Guilherme Machado Pinto

    2017-01-01

    O objetivo deste trabalho consiste em analisar as evidências empíricas de estudos relacionados à inadimplência dentro do contexto brasileiro, verificando os estudos desses aspectos nas diversas regiões do país. Além disso, foram analisadas questões relacionadas ao panorama desses estudos a fim de verificar em quais pontos os trabalhos futuros desse tema podem vir a avançar. A partir da análise dos estudos publicados dentro da temática nota-se a existência de alguns pontos que não são aprofund...

  8. Prácticas de presupuesto de capital: evaluación empírica en un grupo de empresas del sector de la construcción en Colombia

    OpenAIRE

    Ochoa Yepes, Julián

    2014-01-01

    El análisis empírico de presupuesto de capital o valoración de inversiones ha sido un tema ampliamente estudiado principalmente en países desarrollados como Estados Unidos, Reino Unido y Canadá -- Sin embargo la evidencia en países emergentes es escasa -- Mediante este artículo se pretende dar inicio a evidenciar las prácticas de presupuesto de capital a través de un estudio empírico realizado en un grupo de empresas del sector de la construcción en Colombia -- De las empresas encuestadas se ...

  9. Modelling precipitation extremes in the Czech Republic: update of intensity–duration–frequency curves

    Directory of Open Access Journals (Sweden)

    Michal Fusek

    2016-11-01

    Full Text Available Precipitation records from six stations of the Czech Hydrometeorological Institute were subject to statistical analysis with the objectives of updating the intensity–duration–frequency (IDF curves, by applying extreme value distributions, and comparing the updated curves against those produced by an empirical procedure in 1958. Another objective was to investigate differences between both sets of curves, which could be explained by such factors as different measuring instruments, measuring stations altitudes and data analysis methods. It has been shown that the differences between the two sets of IDF curves are significantly influenced by the chosen method of data analysis.

  10. Teoria da agência e franchising: evidência empírica para o caso brasileiro

    OpenAIRE

    Rigoni, Ramon Frigi

    2015-01-01

    O presente estudo tem um duplo objetivo: (i) analisar os determinantes da escolha das firmas por um modelo de franchising na estratégia de expansão de seus negócios, e (ii) analisar como os termos de um contrato de franchising podem potencialmente ser influenciados por questões relativas a compartilhamento de risco, problemas de incentivo relacionados ao risco moral (moral hazard) e restrições de recursos financeiros. Essa discussão se dará seguindo a abordagem empírica proposta por Lafontain...

  11. PENGOLAHAN BUAH DAN BIJI RAMBUTAN SEBAGAI MAKANAN TRADISIONAL KOKTAIL, MANISAN, EMPING BIJI RAMBUTAN DAN OBAT HERBAL YANG BERKHASIAT

    OpenAIRE

    Nuni Widiarti; Sri Wahyuni; F Widhi Mahatmanti

    2013-01-01

    Kegiatan pengabdian kepada masyarakat berupa penyuluhan Pengolahan Buah Dan Biji Rambutan Sebagai Makanan Tradisional Koktail, Manisan, Emping Biji Rambutan Dan Obat Herbal Yang Berkhasiat bertujuan untuk memberikan pengetahuan kepada masyarakat khususnya ibu-ibu PKK dukuh kanggan Desa Wringinputih terhadap manfaat rambutan, dan biji rambutan terhadap kesehatan beserta bagaimana meningkatkan nilai jual rambutan dan biji rambutan pada saat panen raya. Khalayak sasaran dalam pengabdian masyarak...

  12. Main-Memory Operation Buffering for Efficient R-Tree Update

    DEFF Research Database (Denmark)

    Jensen, Christian Søndergaard; Saltenis, Simonas; Biveinis, Laurynas

    2007-01-01

    the buffering of update operations in main memory as well as the grouping of operations to reduce disk I/O. In particular, operations are performed in bulk so that multiple operations are able to share I/O. The paper presents an analytical cost model that is shown to be accurate by empirical studies...... the main memory that is indeed available, or do not support some of the standard index operations. Assuming a setting where the index updates need not be written to disk immediately, we propose an R-tree-based indexing technique that does not exhibit any of these drawbacks. This technique exploits...

  13. DOE interpretations Guide to OSH standards. Update to the Guide

    Energy Technology Data Exchange (ETDEWEB)

    1994-03-31

    Reflecting Secretary O`Leary`s focus on occupational safety and health, the Office of Occupational Safety is pleased to provide you with the latest update to the DOE Interpretations Guide to OSH Standards. This Guide was developed in cooperation with the Occupational Safety and Health Administration, which continued it`s support during this last revision by facilitating access to the interpretations found on the OSHA Computerized Information System (OCIS). This March 31, 1994 update contains 123 formal in letter written by OSHA. As a result of the unique requests received by the 1-800 Response Line, this update also contains 38 interpretations developed by DOE. This new occupational safety and health information adds still more important guidance to the four volume reference set that you presently have in your possession.

  14. DOE interpretations Guide to OSH standards. Update to the Guide

    Energy Technology Data Exchange (ETDEWEB)

    1994-03-31

    Reflecting Secretary O`Leary`s focus on occupational safety and health, the Office of Occupational Safety is pleased to provide you with the latest update to the DOE Interpretations Guide to OSH Standards. This Guide was developed in cooperation with the Occupational Safety and Health Administration, which continued its support during this last revision by facilitating access to the interpretations found on the OSHA Computerized Information System (OCIS). This March 31, 1994 update contains 123 formal interpretation letters written by OSHA. As a result of the unique requests received by the 1-800 Response Line, this update also contains 38 interpretations developed by DOE. This new occupational safety and health information adds still more important guidance to the four volume reference set that you presently have in your possession.

  15. DOE interpretations Guide to OSH standards. Update to the Guide

    Energy Technology Data Exchange (ETDEWEB)

    1994-03-31

    Reflecting Secretary O`Leary`s focus on occupational safety and health, the Office of Occupational Safety is pleased to provide you with the latest update to the DOE Interpretations Guide to OSH Standards. This Guide was developed in cooperation with the Occupational Safety and Health Administration, which continued its support during this last revision by facilitating access to the interpretations found on the OSHA Computerized Information System (OCIS). This March 31, 1994 update contains 123 formal interpretation letters written OSHA. As a result of the unique requests received by the 1-800 Response Line, this update also contains 38 interpretations developed by DOE. This new occupational safety and health information adds still more important guidance to the four volume reference set that you presently have in your possession.

  16. Evaluación de la orientación empática en estudiantes de medicina de la Universidad del Norte. Barranquilla (Colombia

    Directory of Open Access Journals (Sweden)

    Luz Marina Alonso Palacio

    2013-01-01

    Full Text Available Objetivo: Determinar el nivel de orientación empática de los estudiantes de medicina de la Universidad del Norte. Materiales y Métodos: Investigación de tipo descriptiva transversal. La población es - taba constituida por 859 estudiantes, de la cual se tomó una muestra de 345 estudiantes voluntarios (niveles: 1°, 2°, 3°, 4° y 5° año, (1°. n = 128, 2º. n = 102, 3°. n = 38, 4°. n = 41, y 5°. n = 36. Se aplicó, en 2012, la versión en español de la Escala de Empatía Médica de Jefferson ( EEMJ para estudiantes de medicina (versión S, validada en México y Chile y adaptada culturalmente a Colombia mediante el método de validación por criterio de jueces, se calculó: promedio, desviación y se aplicó análisis de varianza bifactorial para diferencia de medias y evaluar interacción entre las variables estudiadas. Resultados: La orientación empática presentó valores ubicados por encima del valor cen - tral del rango de la escala que oscila entre 20 y 140. No se encontraron diferencias signi - ficativas por género ni por año en las puntuaciones. Conclusiones: Los promedios de orientación empática presentaron tendencia casi cons - tante con fluctuaciones no significativas. Sería de gran valor investigar otras variables que pueden afectar la empatía.

  17. Los conceptos innatos en la obra de Chomsky: definición y propuesta de un método empírico para su estudio

    Directory of Open Access Journals (Sweden)

    Oliver Müller

    2013-06-01

    Full Text Available Este artículo versa sobre los conceptos innatos: su definición, de acuerdo a la obra lingüística de Noam Chomsky, y el esbozo de un método que permita su estudio. A manera de introducción se refieren algunas concepciones académicas sobre la adquisición conceptual y se comenta la falta de un método de estudio empírico de los conceptos nativos. Enseguida, se presenta la definición que a lo largo del tiempo ha defendido Chomsky sobre dichos conceptos. Finalmente, se instauran de manera teórica las condiciones de un procedimiento empírico para el estudio de los conceptos innatos, titulado análisis semántico de corpus.

  18. Plutarque contre Colotès contre Empédocle Plutarch against Colotes against Empedocles Plutarco contro Colote contro Empedocle

    Directory of Open Access Journals (Sweden)

    Alain Gigandet

    2013-05-01

    Full Text Available In the section of Against Colotes dedicated to the polemic that the Epicurean, in his writing, developed against Empedocles, Plutarch uses what he considers a bad procedure to traverse the area of dialectic and to arrive at that of the principles of Atomist physics, whose incoherence he feigns to demonstrate.Dans la partie du Contre Colotès consacrée à la polémique que l’épicurien, dans son écrit, développait contre Empédocle, Plutarque utilise ce qu’il considère comme un mauvais procès pour passer du terrain dialectique à celui des principes de la physique atomiste, dont il prétend montrer l’incohérence.Dans la partie du Contre Colotès consacrée à la polémique que l’épicurien, dans son écrit, développait contre Empédocle, Plutarque utilise ce qu’il considère comme un mauvais procès pour passer du terrain dialectique à celui des principes de la physique atomiste, dont il prétend montrer l’incohérence.

  19. Bioenergy Technologies Office Multi-Year Program Plan: November 2014 Update

    Energy Technology Data Exchange (ETDEWEB)

    None

    2014-11-01

    This is the November 2014 Update to the Multi-Year Program Plan, which sets forth the goals and structure of the Bioenergy Technologies Office. It identifies the RDD&D activities the Office will focus on over the next four years.

  20. Bioenergy Technologies Office Multi-Year Program Plan: March 2015 Update

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2015-03-01

    This is the March 2015 Update to the Multi-Year Program Plan, which sets forth the goals and structure of the Bioenergy Technologies Office. It identifies the RDD&D activities the Office will focus on over the next four years.

  1. 76 FR 9502 - Medicare Program; Home Health Prospective Payment System Rate Update for Calendar Year 2011...

    Science.gov (United States)

    2011-02-18

    ... [CMS-1510-F2] RIN 0938-AP88 Medicare Program; Home Health Prospective Payment System Rate Update for... set forth an update to the Home Health Prospective Payment System (HH PPS) rates, including: The... the Medicare prospective payment system for HHAs. This correcting amendment corrects a technical error...

  2. Bancos Cooperativos y Sociedades de Ahorro y Crédito en El Salvador: modelo de supervisión prudencial y análisis empírico del coeficiente de solvencia

    OpenAIRE

    Hernández, Ana Verónica

    2013-01-01

    Estudio bibliográfico empírico, con el que se presenta una propuesta de supervisión para la superintendencia financiera de El Salvador, que incluye requisitos mínimos a considerar por el auditor, tomando como base Basilea II, III y siguiendo el Modelo OSFI de Canadá. Además se presenta un estudio empírico sobre los determinantes del coeficiente patrimonial en bancos cooperativos y sociedades de ahorro y crédito de El Salvador. Economía Financiera y Contabilidad Máster en Investigación ...

  3. Design and development for updating national 1:50,000 topographic databases in China

    Directory of Open Access Journals (Sweden)

    CHEN Jun

    2010-02-01

    Full Text Available 1.1 Objective Map databases are irreplaceable national treasure of immense importance. Their currency referring to its consistency with respect to the real world plays a critical role in its value and applications. The continuous updating of map databases at 1:50,000 scales is a massive and difficult task for larger countries of the size of more than several million’s kilometer squares. This paper presents the research and technological development to support the national map updating at 1:50,000 scales in China, including the development of updating models and methods, production tools and systems for large-scale and rapid updating, as well as the design and implementation of the continuous updating workflow. 1.2 Methodology The updating of map databases is different than its original creation, and a number of new problems should be solved, such as change detection using latest multi-source data, incremental object revision and relation amendment. The methodology of this paper consists of the following three parts: 1 Examine the four key aspects of map database updating and develop basic updating models/methods, such as currentness-oriented integration of multi-resource data, completeness-based incremental change detection in the context of existing datasets, consistency-aware processing of updated data sets, and user-friendly propagation and services of updates. 2 Design and develop specific software tools and packages to support the large-scale updating production with high resolution imagery and large-scale data generalization, such as map generalization, GIS-supported change interpretation from imagery, DEM interpolation, image matching-based orthophoto generation, data control at different levels. 3 Design a national 1:50,000 databases updating strategy and its production workflow, including a full coverage updating pattern characterized by all element topographic data modeling, change detection in all related areas, and whole process

  4. Circulating Endothelial Microparticles: A Key Hallmark of Atherosclerosis Progression

    Directory of Open Access Journals (Sweden)

    Keshav Raj Paudel

    2016-01-01

    Full Text Available The levels of circulating microparticles (MPs are raised in various cardiovascular diseases. Their increased level in plasma is regarded as a biomarker of alteration in vascular function. The prominent MPs present in blood are endothelial microparticles (EMPs described as complex submicron (0.1 to 1.0 μm vesicles like structure, released in response to endothelium cell activation or apoptosis. EMPs possess both physiological and pathological effects and may promote oxidative stress and vascular inflammation. EMPs release is triggered by inducer like angiotensin II, lipopolysaccharide, and hydrogen peroxide leading to the progression of atherosclerosis. However, there are multiple physiological pathways for EMPs generation like NADPH oxidase derived endothelial ROS formation, Rho kinase pathway, and mitogen-activated protein kinases. Endothelial dysfunction is a key initiating event in atherosclerotic plaque formation. Atheroemboli, resulting from ruptured carotid plaques, is a major cause of stroke. Increasing evidence suggests that EMPs play an important role in the pathogenesis of cardiovascular disease, acting as a marker of damage, either exacerbating disease progression or triggering a repair response. In this regard, it has been suggested that EMPs have the potential to act as biomarkers of disease status. This review aims to provide updated information of EMPs in relation to atherosclerosis pathogenesis.

  5. Updating the School Counseling Research Agenda: A Delphi Study

    Science.gov (United States)

    Villares, Elizabeth; Dimmitt, Carey

    2017-01-01

    The authors updated an earlier Delphi study identifying the research priorities for school counseling (Dimmitt et al., 2005). A 29-member expert panel selected research questions from the prior study, generated new questions, and rank ordered the combined set. The results provide guidance for prioritizing dissertation topics, targeting future…

  6. Antibodies against PfEMP1, RIFIN, MSP3 and GLURP are acquired during controlled Plasmodium falciparum malaria infections in naïve volunteers

    DEFF Research Database (Denmark)

    Turner, Louise; Wang, Christian W; Lavstsen, Thomas

    2011-01-01

    Antibodies to polymorphic antigens expressed during the parasites erythrocytic stages are important mediators of protective immunity against P. falciparum malaria. Therefore, polymorphic blood stage antigens like MSP3, EBA-175 and GLURP and variant surface antigens PfEMP1 and RIFIN are considered...

  7. Structural Studies on Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) Malaria Antigens Using Small Angle X-Ray Scattering (SAXS)

    DEFF Research Database (Denmark)

    Christoffersen, Stig

    Chemistry (App I) [1]. VAR2CSA binds specifically to CSA in the placental tissue of pregnant women hereby causing severe malaria symptoms endangering both mother and child. The minimal VAR2CSA region required to effectively bind CSA was determined to be the N-terminal DBL domain, DBL2X which we locate......Infection with the pathogenic Plasmodium falciparum parasite causes the potentially deadly Malaria disease which leads to over 1 million fatalities each year according to the WHO (World Health Organization). Individuals subjected to multiple infections gradually become immune to the disease...... symptoms and vaccine research is focused on trying to mimic or advance this immune acquisition. Immunity is primarily caused by acquisition of antibodies directed against a family of Plasmodium protein antigens called PfEMP1s located on the surface of infected erythrocytes. The PfEMP1 proteins are adhesive...

  8. Information dissemination model for social media with constant updates

    Science.gov (United States)

    Zhu, Hui; Wu, Heng; Cao, Jin; Fu, Gang; Li, Hui

    2018-07-01

    With the development of social media tools and the pervasiveness of smart terminals, social media has become a significant source of information for many individuals. However, false information can spread rapidly, which may result in negative social impacts and serious economic losses. Thus, reducing the unfavorable effects of false information has become an urgent challenge. In this paper, a new competitive model called DMCU is proposed to describe the dissemination of information with constant updates in social media. In the model, we focus on the competitive relationship between the original false information and updated information, and then propose the priority of related information. To more effectively evaluate the effectiveness of the proposed model, data sets containing actual social media activity are utilized in experiments. Simulation results demonstrate that the DMCU model can precisely describe the process of information dissemination with constant updates, and that it can be used to forecast information dissemination trends on social media.

  9. Organização de Reparo na Conversa Cotidiana: um Estudo Empírico

    Directory of Open Access Journals (Sweden)

    Caroline Caputo Pires

    2017-02-01

    Full Text Available O presente trabalho visa analisar ocorrências de trajetórias de reparo com dados em fala-em-interação em uma filmagem com quatro brasileiros intercambistas na Alemanha, no qual apresentam suas experiências no período de um ano em contato com outra língua e cultural. Assim, para descrever o fenômeno de reparo (SIDNELL, 2010, GARCEZ, 2008, LODER, 2005 é importante destacar que os participantes em interação e demonstrável pela articulação de análises comunicacionais, o fenômeno do reparo é importante para a interpretação em relação à correção na fala-em-interação, na medida em que o reparo se refere às práticas que participantes usam para contornar problemas ou obstáculos na fala, audição ou compreensão da fala. Enfatiza-se, nesse trabalho, que os estudos sobre reparo na fala-em-interação se deram no campo dos estudos da Análise da Conversa, entre estudiosos que se interessam nas ações cotidianas na vida das pessoas. Dessa forma, a base empírica desse trabalho focalizará os conceitos da Análise da Conversa, fenômenos de reparo em uma filmagem de uma interação de brasileiros em intercambio no ano de 2014. Os dados empíricos fazem parte do projeto da UFMG que investiga perspectivas comunicativas e as atitudes extracomunicativas que indivíduos realizam e desenvolvem no decorrer de um encontro intercultural de duração maior.

  10. Age-related differences in working memory updating components.

    Science.gov (United States)

    Linares, Rocío; Bajo, M Teresa; Pelegrina, Santiago

    2016-07-01

    The aim of this study was to investigate possible age-related changes throughout childhood and adolescence in different component processes of working memory updating (WMU): retrieval, transformation, and substitution. A set of numerical WMU tasks was administered to four age groups (8-, 11-, 14-, and 21-year-olds). To isolate the effect of each of the WMU components, participants performed different versions of a task that included different combinations of the WMU components. The results showed an expected overall decrease in response times and an increase in accuracy performance with age. Most important, specific age-related changes in the retrieval component were found, demonstrating that the effect of retrieval on accuracy was larger in children than in adolescents or young adults. These findings indicate that the availability of representations from outside the focus of attention may change with age. Thus, the retrieval component of updating could contribute to the age-related changes observed in the performance of many updating tasks. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. AGU's Updated Scientific Integrity and Professional Ethics Policy

    Science.gov (United States)

    McPhaden, M. J.

    2017-12-01

    AGU'S mission is to promote discovery in Earth and space science for the benefit of humanity. This mission can only be accomplished if all those engaged in the scientific enterprise uphold the highest standards of scientific integrity and professional ethics. AGU's Scientific Integrity and Professional Ethics Policy provides a set of principles and guidelines for AGU members, staff, volunteers, contractors, and non-members participating in AGU sponsored programs and activities. The policy has recently been updated to include a new code of conduct that broadens the definition of scientific misconduct to include discrimination, harassment, and bullying. This presentation provides the context for what motivated the updated policy, an outline of the policy itself, and a discussion of how it is being communicated and applied.

  12. Updating working memory in aircraft noise and speech causes different fMRI activations

    OpenAIRE

    Sætrevik, Bjørn; Sörqvist, Patrik

    2014-01-01

    The present study used fMRI/BOLD neuroimaging to investigate how visual-verbal working memory is updated when exposed to three different background-noise conditions: speech noise, aircraft noise and silence. The number-updating task that was used can distinguish between ?substitution processes,? which involve adding new items to the working memory representation and suppressing old items, and ?exclusion processes,? which involve rejecting new items and maintaining an intact memory set. The cu...

  13. Updated Scar Management Practical Guidelines: Non-invasive and invasive measures

    NARCIS (Netherlands)

    Monstrey, S.; Middelkoop, E.; Vranckx, J.J.; Bassetto, F.; Ziegler, U.E.; Meaume, S.; Teot, L.

    2014-01-01

    Hypertrophic scars and keloids can be aesthetically displeasing and lead to severe psychosocial impairment. Many invasive and non-invasive options are available for the plastic (and any other) surgeon both to prevent and to treat abnormal scar formation. Recently, an updated set of practical

  14. Responsabilidad Social Corporativa de la Empresas de Distribución Comercial Españolas. Evidencias Empíricas

    OpenAIRE

    Díaz Heredia, Isabel

    2013-01-01

    En este Trabajo Fin de Máster se analiza la Responsabilidad Social Corporativa de las grandes empresas de distribución comercial en España. En él se trata el desarrollo teórico de la RSC, el sector de la distribución comercial y, por último, se realiza un estudio empírico para el análisis del grado de RSC on-line en las grandes empresas de distribución comercial.

  15. Ayudas públicas a la innovación: una evidencia empírica de la PYME industrial del sureste mexicano

    Directory of Open Access Journals (Sweden)

    Gabriel Góngora-Biachi

    2009-08-01

    Full Text Available Este trabajo tiene como propósito estudiar la existencia de tres tipos de sesgo en el proceso de solicitud y concesión de ayudas a la innovación a la PYME industrial en México (sesgo de motivación, sesgo de selección administrativa y sesgo de información. Para ello se realiza un estudio empírico sobre 169 PYME industriales, subvencionadas y no subvencionadas. Los datos del estudio empírico han sido recogidos a través de un cuestionario dirigido al gerente de la empresa. Los resultados muestran que las empresas que solicitan ayudas públicas cuentan con una mejor tecnología. Las empresas elegidas por la Administración para otorgar las ayudas tienen tecnología fuerte-buena, estrategia exploradora-analizadora y una mayor proporción de exportaciones. Finalmente se obtiene, al analizar el sesgo de información en las empresas que no solicitan ayudas, que las mejor informadas se caracterizan por tener un mayor grado de exportación y ser más antiguas.

  16. Inverse Problems in a Bayesian Setting

    KAUST Repository

    Matthies, Hermann G.

    2016-02-13

    In a Bayesian setting, inverse problems and uncertainty quantification (UQ)—the propagation of uncertainty through a computational (forward) model—are strongly connected. In the form of conditional expectation the Bayesian update becomes computationally attractive. We give a detailed account of this approach via conditional approximation, various approximations, and the construction of filters. Together with a functional or spectral approach for the forward UQ there is no need for time-consuming and slowly convergent Monte Carlo sampling. The developed sampling-free non-linear Bayesian update in form of a filter is derived from the variational problem associated with conditional expectation. This formulation in general calls for further discretisation to make the computation possible, and we choose a polynomial approximation. After giving details on the actual computation in the framework of functional or spectral approximations, we demonstrate the workings of the algorithm on a number of examples of increasing complexity. At last, we compare the linear and nonlinear Bayesian update in form of a filter on some examples.

  17. Inverse Problems in a Bayesian Setting

    KAUST Repository

    Matthies, Hermann G.; Zander, Elmar; Rosić, Bojana V.; Litvinenko, Alexander; Pajonk, Oliver

    2016-01-01

    In a Bayesian setting, inverse problems and uncertainty quantification (UQ)—the propagation of uncertainty through a computational (forward) model—are strongly connected. In the form of conditional expectation the Bayesian update becomes computationally attractive. We give a detailed account of this approach via conditional approximation, various approximations, and the construction of filters. Together with a functional or spectral approach for the forward UQ there is no need for time-consuming and slowly convergent Monte Carlo sampling. The developed sampling-free non-linear Bayesian update in form of a filter is derived from the variational problem associated with conditional expectation. This formulation in general calls for further discretisation to make the computation possible, and we choose a polynomial approximation. After giving details on the actual computation in the framework of functional or spectral approximations, we demonstrate the workings of the algorithm on a number of examples of increasing complexity. At last, we compare the linear and nonlinear Bayesian update in form of a filter on some examples.

  18. Shipment security update - 2003

    International Nuclear Information System (INIS)

    Patterson, John; Anne, Catherine

    2003-01-01

    At the 2002 RERTR, NAC reported on the interim measures taken by the U.S. Nuclear Regulatory Commission to enhance the security afforded to shipments of spent nuclear fuel. Since that time, there have been a number of additional actions focused on shipment security including training programs sponsored by the U.S. Department of Transportation and the Electric Power Research Council, investigation by the Government Accounting Office, and individual measures taken by shippers and transportation agents. The paper will present a status update regarding this dynamic set of events and provide an objective assessment of the cost, schedule and technical implications of the changing security landscape. (author)

  19. Setting the standard: The IAEA safety standards set the global reference

    International Nuclear Information System (INIS)

    Williams, L.

    2003-01-01

    For the IAEA, setting and promoting standards for nuclear radiation, waste, and transport safety have been priorities from the start, rooted in the Agency's 1957 Statute. Today, a corpus of international standards are in place that national regulators and industries in many countries are applying, and more are being encouraged and assisted to follow them. Considerable work is done to keep safety standards updated and authoritative. They cover five main areas: the safety of nuclear facilities; radiation protection and safety of radiation sources; safe management of radioactive waste; safe transport of radioactive material; and thematic safety areas, such as emergency preparedness or legal infrastructures. Overall, the safety standards reflect an international consensus on what constitutes a high level of safety for protecting people and the environment. All IAEA Member States can nominate experts for the Agency standards committees and provide comments on draft standards. Through this ongoing cycle of review and feedback, the standards are refined, updated, and extended where needed

  20. a Bottom-Up Geosptial Data Update Mechanism for Spatial Data Infrastructure Updating

    Science.gov (United States)

    Tian, W.; Zhu, X.; Liu, Y.

    2012-08-01

    Currently, the top-down spatial data update mechanism has made a big progress and it is wildly applied in many SDI (spatial data infrastructure). However, this mechanism still has some issues. For example, the update schedule is limited by the professional department's project, usually which is too long for the end-user; the data form collection to public cost too much time and energy for professional department; the details of geospatial information does not provide sufficient attribute, etc. Thus, how to deal with the problems has become the effective shortcut. Emerging Internet technology, 3S technique and geographic information knowledge which is popular in the public promote the booming development of geoscience in volunteered geospatial information. Volunteered geospatial information is the current "hotspot", which attracts many researchers to study its data quality and credibility, accuracy, sustainability, social benefit, application and so on. In addition to this, a few scholars also pay attention to the value of VGI to support the SDI updating. And on that basis, this paper presents a bottom-up update mechanism form VGI to SDI, which includes the processes of match homonymous elements between VGI and SDI vector data , change data detection, SDI spatial database update and new data product publication to end-users. Then, the proposed updating cycle is deeply discussed about the feasibility of which can detect the changed elements in time and shorten the update period, provide more accurate geometry and attribute data for spatial data infrastructure and support update propagation.

  1. Working Memory Updating Latency Reflects the Cost of Switching between Maintenance and Updating Modes of Operation

    Science.gov (United States)

    Kessler, Yoav; Oberauer, Klaus

    2014-01-01

    Updating and maintenance of information are 2 conflicting demands on working memory (WM). We examined the time required to update WM (updating latency) as a function of the sequence of updated and not-updated items within a list. Participants held a list of items in WM and updated a variable subset of them in each trial. Four experiments that vary…

  2. FRMAC Updates

    International Nuclear Information System (INIS)

    Mueller, P.

    1995-01-01

    This talks describes updates in the following updates in FRMAC publications concerning radiation emergencies: Monitoring and Analysis Manual; Evaluation and Assessment Manual; Handshake Series (Biannual) including exercises participated in; environmental Data and Instrument Transmission System (EDITS); Plume in a Box with all radiological data stored onto a hand-held computer; and courses given

  3. APPRIS 2017: principal isoforms for multiple gene sets

    Science.gov (United States)

    Rodriguez-Rivas, Juan; Di Domenico, Tomás; Vázquez, Jesús; Valencia, Alfonso

    2018-01-01

    Abstract The APPRIS database (http://appris-tools.org) uses protein structural and functional features and information from cross-species conservation to annotate splice isoforms in protein-coding genes. APPRIS selects a single protein isoform, the ‘principal’ isoform, as the reference for each gene based on these annotations. A single main splice isoform reflects the biological reality for most protein coding genes and APPRIS principal isoforms are the best predictors of these main proteins isoforms. Here, we present the updates to the database, new developments that include the addition of three new species (chimpanzee, Drosophila melangaster and Caenorhabditis elegans), the expansion of APPRIS to cover the RefSeq gene set and the UniProtKB proteome for six species and refinements in the core methods that make up the annotation pipeline. In addition APPRIS now provides a measure of reliability for individual principal isoforms and updates with each release of the GENCODE/Ensembl and RefSeq reference sets. The individual GENCODE/Ensembl, RefSeq and UniProtKB reference gene sets for six organisms have been merged to produce common sets of splice variants. PMID:29069475

  4. Evidencia Empírica sobre la Paridad del Poder Adquisitivo en México Evidencia Empírica sobre la Paridad del Poder Adquisitivo en México

    Directory of Open Access Journals (Sweden)

    Lorena Medina

    2012-02-01

    Full Text Available This article describes the application of methods recently developed for testing stationarity in the Mexico/US real exchange rate, while allowing for an unknown number of structural breaks in the long-run level of the series. In our empirical implementation, inference relies on bootstraped critical values. As a result, we present unambiguous empirical evidence on the stationarity of the real exchange rate, thus favoring long-run purchasing power parity. En este artículo se describe la aplicación de métodos recientes para probar la estacionariedad del tipo de cambio real peso/dólar, tomando en cuenta la presencia de un número desconocido de cambios estructurales en el nivel de largo plazo de la serie. En nuestra implementación empírica, la inferencia se basa en valores críticos fundamentados en técnicas de remuestreo. Se presenta evidencia contundente sobre la estacionariedad del tipo de cambio real, apoyando así la hipótesis de la paridad del poder adquisitivo.

  5. Determinantes de la equidad en el financiamiento de los medicamentos en Argentina: un estudio empírico

    OpenAIRE

    Dondo, Mariana; Monsalvo, Mauricio; Garibaldi, Lucas A.

    2016-01-01

    Resumen Los medicamentos constituyen un alto porcentaje del gasto en salud de los hogares, por eso, tener un sistema progresivo de financiamiento de medicamentos es fundamental para lograr un sistema de salud equitativo. Se ha propuesto que los determinantes de la equidad en el financiamiento son socioeconómicos, demográficos y asociados a la intervención pública, sin embargo, se ha avanzado poco en su evaluación empírica y en la cuantificación de su importancia relativa. En este trabajo esti...

  6. Límites de las formas organizacionales hibridas: Evaluación teórica y análisis de investigaciones empíricas

    Directory of Open Access Journals (Sweden)

    Maria Valentina Locher

    2017-01-01

    Full Text Available El concepto de formas organizacionales híbridas resulta clave para las investigaciones empíricas realizadas en el marco de la Nueva Economía Institucional. Las formas híbridas suelen considerarse un avance de dicho programa, sin embargo, aquí se argumentará lo contrario: este concepto evidencia limitaciones en las hipótesis fundamentales de aquel programa de investigaciones económicas. En este trabajo se muestra cómo el concepto de formas híbridas es utilizado para interpretar una realidad socioeconómica que desborda los límites de las formas mercantiles de coordinación económica. Luego se mostrará que ello, en el marco de la Nueva Economía Institucional, supone una paradoja insalvable. Finalmente se ensayan nuevas hipótesis para superar esta limitación y se muestran las consecuencias de este problema sobre dos investigaciones empíricas que desbordaron los límites de las formas organizacionales hibridas.

  7. Environmental management plan (EMP) for Melamchi water supply project, Nepal.

    Science.gov (United States)

    Khadka, Ram B; Khanal, Anil B

    2008-11-01

    More than 1.5 million people live in the Kathmandu valley. The valley is facing an extreme shortage of water supply. At the same time the demand is escalating rapidly. To address this issue of scarcity of water, the government of Nepal has proposed a project of inter-basin transfer of water from Melamchi River located 40 km north-east of the Kathmandu valley. The project will cover two districts and three municipalities and will potentially have significant impacts on the environment. In accordance with the Environmental Protection Regulation of Nepal (1997), the Melamchi Water Supply Project (MWSP) has undergone an EIA during the feasibility study stage of the proposed project. The recommendations contained in the EIA were integrated into the project design for implementation in 2006. This paper summarizes the background of MWSP, the environmental concerns described in the EIA and the status of Environmental Management Plan (EMP) developed to address environmental compliance and other issues involving participation and support of the local people. This paper also provides some lessons to learn on the modalities of addressing the demands and grievances of the local people concerning environmental management.

  8. World Allergy Organization Anaphylaxis Guidelines: 2013 update of the evidence base.

    Science.gov (United States)

    Simons, F Estelle R; Ardusso, Ledit R F; Dimov, Vesselin; Ebisawa, Motohiro; El-Gamal, Yehia M; Lockey, Richard F; Sanchez-Borges, Mario; Senna, Gian Enrico; Sheikh, Aziz; Thong, Bernard Y; Worm, Margitta

    2013-01-01

    The World Allergy Organization (WAO) Guidelines for the assessment and management of anaphylaxis are a widely disseminated and used resource for information about anaphylaxis. They focus on patients at risk, triggers, clinical diagnosis, treatment in health care settings, self-treatment in the community, and prevention of recurrences. Their unique strengths include a global perspective informed by prior research on the global availability of essentials for anaphylaxis assessment and management and a global agenda for anaphylaxis research. Additionally, detailed colored illustrations are linked to key concepts in the text [Simons et al.: J Allergy Clin Immunol 2011;127:593.e1-e22]. The recommendations in the original WAO Anaphylaxis Guidelines for management of anaphylaxis in health care settings and community settings were based on evidence published in peer-reviewed, indexed medical journals to the end of 2010. These recommendations remain unchanged and clinically relevant. An update of the evidence base was published in 2012 [Simons et al.: Curr Opin Allergy Clin Immunol 2012;12:389-399]. In 2012 and early 2013, major advances were reported in the following areas: further characterization of patient phenotypes; development of in vitro tests (for some allergens) that help distinguish clinical risk of anaphylaxis from asymptomatic sensitization; epinephrine (adrenaline) research, including studies of a new epinephrine auto-injector for use in community settings, and randomized controlled trials of immunotherapy to prevent food-induced anaphylaxis. Despite these advances, the need for additional prospective studies, including randomized controlled trials of interventions in anaphylaxis is increasingly apparent. This 2013 Update highlights publications from 2012 and 2013 that further contribute to the evidence base for the recommendations made in the original WAO Anaphylaxis Guidelines. Ideally, it should be used in conjunction with these Guidelines and with the 2012

  9. DATMAN: A reliability data analysis program using Bayesian updating

    International Nuclear Information System (INIS)

    Becker, M.; Feltus, M.A.

    1996-01-01

    Preventive maintenance (PM) techniques focus on the prevention of failures, in particular, system components that are important to plant functions. Reliability-centered maintenance (RCM) improves on the PM techniques by introducing a set of guidelines by which to evaluate the system functions. It also minimizes intrusive maintenance, labor, and equipment downtime without sacrificing system performance when its function is essential for plant safety. Both the PM and RCM approaches require that system reliability data be updated as more component failures and operation time are acquired. Systems reliability and the likelihood of component failures can be calculated by Bayesian statistical methods, which can update these data. The DATMAN computer code has been developed at Penn State to simplify the Bayesian analysis by performing tedious calculations needed for RCM reliability analysis. DATMAN reads data for updating, fits a distribution that best fits the data, and calculates component reliability. DATMAN provides a user-friendly interface menu that allows the user to choose from several common prior and posterior distributions, insert new failure data, and visually select the distribution that matches the data most accurately

  10. Evaluación de un modelo de la brdf a partir de simulaciones con modelos semi-empíricos lineales (sel

    Directory of Open Access Journals (Sweden)

    Edgardo Rafael Medrano Ruedaflores

    2013-07-01

    Full Text Available Los modelos semi-empíricos lineales, también conocidos como modelos lineales basados en kernels, han sido utilizados con relativo éxito en la derivación de parámetros biofísicos de la vegetación a partir de imágenes satelitales. Su construcción se basa en hipótesis difíciles de corroborar y su calibración demanda suponer condiciones de homogeneidad en el sistema suelo-vegetación-atmósfera. Un modelo de la BRDF libre de estas limitaciones es evaluado en este estudio simulando el proceso de dispersión de la radiación solar según diferentes configuraciones de cobertura terrestre. Los datos fueron generados mediante la implementación de cuatro modelos lineales basados en kernels. Se evaluó el ajuste del modelo en cada escenario simulado a través de regresión lineal simple, obteniéndose valores del coeficiente de determinación superiores a 0.98. Los resultados sugieren que es posible utilizar el modelo evaluado en aplicaciones donde actualmente se emplean modelos semi-empíricos lineales.

  11. Memory updating and mental arithmetic

    Directory of Open Access Journals (Sweden)

    Cheng-Ching eHan

    2016-02-01

    Full Text Available Is domain-general memory updating ability predictive of calculation skills or are such skills better predicted by the capacity for updating specifically numerical information? Here, we used multidigit mental multiplication (MMM as a measure for calculating skill as this operation requires the accurate maintenance and updating of information in addition to skills needed for arithmetic more generally. In Experiment 1, we found that only individual differences with regard to a task updating numerical information following addition (MUcalc could predict the performance of MMM, perhaps owing to common elements between the task and MMM. In Experiment 2, new updating tasks were designed to clarify this: a spatial updating task with no numbers, a numerical task with no calculation, and a word task. The results showed that both MUcalc and the spatial task were able to predict the performance of MMM but only with the more difficult problems, while other updating tasks did not predict performance. It is concluded that relevant processes involved in updating the contents of working memory support mental arithmetic in adults.

  12. A compra de votos: uma aproximação empírica

    Directory of Open Access Journals (Sweden)

    Bruno Wilhelm Speck

    2003-05-01

    Full Text Available O artigo aborda o fenômeno da compra de votos no contexto histórico e apresenta dados de um levantamento empírico realizado através de uma pesquisa de opinião após as eleições municipais no Brasil no ano 2000. São discutidas questões relacionadas ao significado da compra de votos no conjunto das questões ligadas à lisura do processo eleitoral. O texto aborda também os problemas enfrentados na pesquisa em função do assunto abordado e soluções metodológicas encontradas.The author presents the results of a national survey on vote buying during the local elections in Braszil in 2000. In his analysis he places vote buying into the broader historical perspective of electoral and other forms of manipulation and corruption. Specific methodological questions of surveys on such critical questions like fraude and corruption are discussed

  13. Hospitals, Part of Community Facilities data set for all eleven counties and twenty-two cities within Middle Georgia. Updated by MGRC and maintained by the GA Dept of Community Affairs., Published in 2000, 1:24000 (1in=2000ft) scale, Middle Georgia Regional Commission.

    Data.gov (United States)

    NSGIC Regional | GIS Inventory — Hospitals dataset current as of 2000. Part of Community Facilities data set for all eleven counties and twenty-two cities within Middle Georgia. Updated by MGRC and...

  14. National Educators' Workshop: Update 2003. Standard Experiments in Engineering, Materials Science, and Technology. Part 2

    Science.gov (United States)

    Prior, Edwin J. (Compiler); Jacobs, James A. (Compiler); Edmonson, William (Compiler); Wilkerson, Amy (Compiler)

    2004-01-01

    The 18th Annual National Educators Workshop [NEW:Update 2003] was a part of NASA Langley s celebration of the Centennial of Controlled, Powered Flight by Orville and Wilbur Wright on December 17, 1903. The conference proceedings from NEW:Update 2003 reflect the Flight 100 theme by first providing a historic perspective on the remarkable accomplishments of the Wright Brothers. The historical perspective set the stag for insights into aeronautics and aerospace structures and materials now and into the future. The NEW:Update 2003 proceedings provide valuable resources to educators and students in the form of visuals, experiments and demonstrations for classes/labs at levels ranging from precollege through college education.

  15. National Educators' Workshop: Update 2003. Standard Experiments in Engineering, Materials Science, and Technology. Part 1

    Science.gov (United States)

    Prior, Edwin J. (Compiler); Jacobs, James A. (Compiler); Edmonson, William (Compiler); Wilkerson, Amy (Compiler)

    2004-01-01

    The 18th Annual National Educators Workshop [NEW:Update 2003] was a part of NASA Langley s celebration of the Centennial of Controlled, Powered Flight by Orville and Wilbur Wright on December 17, 1903. The conference proceedings from NEW:Update 2003 reflect the Flight 100 theme by first providing a historic perspective on the remarkable accomplishments of the Wright Brothers. The historical perspective set the stag for insights into aeronautics and aerospace structures and materials now and into the future. The NEW:Update 2003 proceedings provide valuable resources to educators and students in the form of visuals, experiments and demonstrations for classes/labs at levels ranging from precollege through college education.

  16. Development of JAEA sorption database (JAEA-SDB). Update of sorption/QA data in FY2015

    International Nuclear Information System (INIS)

    Tachi, Yukio; Suyama, Tadahiro

    2016-03-01

    Sorption and diffusion of radionuclides in buffer materials (bentonite) and rocks are the key processes in the safe geological disposal of radioactive waste, because migration of radionuclides in these barrier materials is expected to be diffusion-controlled and retarded by sorption processes. It is therefore necessary to understand the sorption and diffusion processes and develop databases compiling reliable data and mechanistic/predictive models, so that reliable parameters can be set under a variety of geochemical conditions relevant to performance assessment (PA). For this purpose, Japan Atomic Energy Agency (JAEA) has developed databases of sorption and diffusion parameters in bentonites and rocks. These sorption and diffusion databases (SDB/DDB) were firstly developed as an important basis for the H12 PA of high-level radioactive waste disposal, and have been provided through the Web. JAEA has been continuing to improve and update the SDB/DDB in view of potential future data needs, focusing on assuring the desired quality level and testing the usefulness of the databases for possible applications to PA-related parameter setting. The present report focuses on improving and updating of the sorption database (JAEA-SDB) as basis of integrated approach for PA-related K d setting and mechanistic sorption model development. This includes an overview of database structure, contents and functions including additional data evaluation function focusing on statistical data evaluation and grouping of data related to potential perturbations. K d data and their QA results are updated by focusing our recent activities on the K d setting and mechanistic model development. As a result, 11,206 K d data from 83 references were added, total number of K d values in the JAEA-SDB reached about 58,000. The QA/classified K d data reached about 60% for all K d data in JAEA-SDB. The updated JAEA-SDB is expected to make it possible to obtain quick overview of the available data, and to

  17. Work family balance : mito ou aptidão : estudo empírico sobre antecedentes e consequências

    OpenAIRE

    Pedro, Ana Margarida Alexandre

    2016-01-01

    Dissertação de mestrado em Marketing, apresentada à Faculdade de Economia da Universidade de Coimbra, sob a orientação de Arnaldo Fernandes Matos Coelho e Joaquim Luís Medeiros Alcoforado. “Work Family Balance – Mito ou Aptidão? Estudo Empírico Sobre Antecedentes e Consequências” visa contribuir, com base na revisão bibliográfica, para a compreensão de quais as variáveis que contribuem para esse equilíbrio dinâmico e quais as repercussões. Este tema insere-se no Marketing Inter...

  18. How update schemes influence crowd simulations

    International Nuclear Information System (INIS)

    Seitz, Michael J; Köster, Gerta

    2014-01-01

    Time discretization is a key modeling aspect of dynamic computer simulations. In current pedestrian motion models based on discrete events, e.g. cellular automata and the Optimal Steps Model, fixed-order sequential updates and shuffle updates are prevalent. We propose to use event-driven updates that process events in the order they occur, and thus better match natural movement. In addition, we present a parallel update with collision detection and resolution for situations where computational speed is crucial. Two simulation studies serve to demonstrate the practical impact of the choice of update scheme. Not only do density-speed relations differ, but there is a statistically significant effect on evacuation times. Fixed-order sequential and random shuffle updates with a short update period come close to event-driven updates. The parallel update scheme overestimates evacuation times. All schemes can be employed for arbitrary simulation models with discrete events, such as car traffic or animal behavior. (paper)

  19. External RNA Controls Consortium Beta Version Update.

    Science.gov (United States)

    Lee, Hangnoh; Pine, P Scott; McDaniel, Jennifer; Salit, Marc; Oliver, Brian

    2016-01-01

    Spike-in RNAs are valuable controls for a variety of gene expression measurements. The External RNA Controls Consortium developed test sets that were used in a number of published reports. Here we provide an authoritative table that summarizes, updates, and corrects errors in the test version that ultimately resulted in the certified Standard Reference Material 2374. We have noted existence of anti-sense RNA controls in the material, corrected sub-pool memberships, and commented on control RNAs that displayed inconsistent behavior.

  20. A Novel Domain Cassette Identifies Plasmodium falciparum PfEMP1 Proteins Binding ICAM-1 and Is a Target of Cross-Reactive, Adhesion-Inhibitory Antibodies

    DEFF Research Database (Denmark)

    Bengtsson, Anja; Jørgensen, Louise; Rask, Thomas Salhøj

    2013-01-01

    Cerebral Plasmodium falciparum malaria is characterized by adhesion of infected erythrocytes (IEs) to the cerebral microvasculature. This has been linked to parasites expressing the structurally related group A subset of the P. falciparum erythrocyte membrane protein 1 (PfEMP1) family of IE...... to ICAM-1. The ICAM-1-binding capacity of DC4 was mapped to the C-terminal third of its Duffy-binding-like beta 3 domain. DC4 was the target of broadly cross-reactive and adhesion-inhibitory IgG Abs, and levels of DC4-specific and adhesion-inhibitory IgG increased with age among P. falciparum......-exposed children. Our study challenges earlier conclusions that group A PfEMP1 proteins are not central to ICAM-1-specific IE adhesion and support the feasibility of developing a vaccine preventing cerebral malaria by inhibiting cerebral IE sequestration. The Journal of Immunology, 2013, 190: 240-249....

  1. Dynamic stabbing queries with sub-logarithmic local updates for overlapping intervals : Proc. 12th International Computer Science Symposium in Russia

    NARCIS (Netherlands)

    Khramtcova, Elena; Löffler, Maarten

    2017-01-01

    We present a data structure to maintain a set of intervals on the real line subject to fast insertions and deletions of the intervals, stabbing queries, and local updates. Intuitively, a local update replaces an interval by another one of roughly the same size and location. We investigate whether

  2. Antibodies to ICAM1-binding PfEMP1-DBLβ are biomarkers of protective immunity to malaria in a cohort of young children from Papua New Guinea

    DEFF Research Database (Denmark)

    Tessema, Sofonias K; Utama, Digjaya; Chesnokov, Olga

    2018-01-01

    Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) mediates parasite sequestration to the cerebral microvasculature via binding of DBLβ domains to Intercellular Adhesion Molecule 1 (ICAM1) and is associated with severe cerebral malaria. In a cohort of 187 young children from Papua New ...

  3. Determinantes de la inversión en I+D: un análisis empírico en empresas europeas de software y servicios informáticos

    OpenAIRE

    Fernández López, Javier

    2013-01-01

    Estudio empírico de los factores determinantes de la inversión en I+D en empresas europeas de software y servicios informáticos entre 2004-2010 Economía Financiera y Contabilidad Máster en Contabilidad y Gestión Financiera

  4. Prediction-error variance in Bayesian model updating: a comparative study

    Science.gov (United States)

    Asadollahi, Parisa; Li, Jian; Huang, Yong

    2017-04-01

    In Bayesian model updating, the likelihood function is commonly formulated by stochastic embedding in which the maximum information entropy probability model of prediction error variances plays an important role and it is Gaussian distribution subject to the first two moments as constraints. The selection of prediction error variances can be formulated as a model class selection problem, which automatically involves a trade-off between the average data-fit of the model class and the information it extracts from the data. Therefore, it is critical for the robustness in the updating of the structural model especially in the presence of modeling errors. To date, three ways of considering prediction error variances have been seem in the literature: 1) setting constant values empirically, 2) estimating them based on the goodness-of-fit of the measured data, and 3) updating them as uncertain parameters by applying Bayes' Theorem at the model class level. In this paper, the effect of different strategies to deal with the prediction error variances on the model updating performance is investigated explicitly. A six-story shear building model with six uncertain stiffness parameters is employed as an illustrative example. Transitional Markov Chain Monte Carlo is used to draw samples of the posterior probability density function of the structure model parameters as well as the uncertain prediction variances. The different levels of modeling uncertainty and complexity are modeled through three FE models, including a true model, a model with more complexity, and a model with modeling error. Bayesian updating is performed for the three FE models considering the three aforementioned treatments of the prediction error variances. The effect of number of measurements on the model updating performance is also examined in the study. The results are compared based on model class assessment and indicate that updating the prediction error variances as uncertain parameters at the model

  5. La fuerza de los lazos: una exploración teórica y empírica de sus múltiples significados

    Directory of Open Access Journals (Sweden)

    Irene Cruz Gómez

    2013-01-01

    Full Text Available La fuerza del vínculo es una de las características recurrentemente estudiadas en las redes personales. Es un dato aparentemente sencillo de generar, con una potencial capacidad predictiva sobre los intercambios dentro de la relación y de la posición del contacto dentro de la red. Sin embargo, la gran diversidad de indicadores que se emplean en la literatura para medir esta fuerza del vínculo da fe de la vaguedad en la definición del concepto y las consecuentes dificultades para operativizarlo, dando lugar a resultados ambivalentes en su observación empírica. Con este trabajo de revisión teórica, metodológica y empírica se pre- tende ofrecer una base sobre la cual contribuir a la delimitación del concepto. Se propone una dimensionalización teórica de la noción, distinguiendo sus aspectos expresivos, sociales y estructurales, y a continuación se compara el comportamiento de diversos indicadores de las distintas dimensiones empleando una muestra de 441 redes personales y 13.230 relaciones provenientes de una encuesta realizada en Cataluña entre 2009 y 2010.

  6. Development of JAEA sorption database (JAEA-SDB). Update of data evaluation functions and sorption/QA data

    International Nuclear Information System (INIS)

    Tachi, Yukio; Suyama, Tadahiro; Ochs, Michael; Ganter, Charlotte

    2011-03-01

    Sorption and diffusion of radionuclides in buffer materials (bentonite) and rocks are the key processes in the safe geological disposal of radioactive waste, because migration of radionuclides in this barrier is expected to be diffusion-controlled and retarded by sorption processes. It is therefore necessary to understand the sorption and diffusion processes and develop database compiling reliable data and mechanistic/predictive models, so that reliable parameters can be set under a variety of geochemical conditions relevant to performance assessment (PA). For this purpose, Japan Atomic Energy Agency (JAEA) has developed databases of sorption and diffusion parameters in buffer materials (bentonite) and rocks. These sorption and diffusion databases (SDB/DDB) were firstly developed as an important basis for the H12 PA of high-level radioactive waste disposal, and have been provided through the Web. JAEA has been continuing to improve and update the SDB/DDB in view of potential future data needs, focusing on assuring the desired quality level and testing the usefulness of the databases for possible applications to PA-related parameter setting. The present report focuses on developing and updating of the sorption database (JAEA-SDB) as basis of integrated approach for PA-related K d setting. This includes an overview of database structure, contents and functions including additional data evaluation function focusing on multi-parameter dependence, operating method, PA-related applications of the web-based JAEA-SDB. K d data and their QA results are updated by focusing our recent activities on the K d setting and mechanistic model development. As a result, 4,250 K d data from 32 references are added, total K d values in the JAEA-SDB are about 28,540. The QA/classified K d data are about 39% for all K d data in JAEA-SDB. The updated JAEA-SDB is expected to make it possible to obtain quick overview of the available data, and to have suitable access to the respective data

  7. Decentralized Consistent Updates in SDN

    KAUST Repository

    Nguyen, Thanh Dang

    2017-04-10

    We present ez-Segway, a decentralized mechanism to consistently and quickly update the network state while preventing forwarding anomalies (loops and blackholes) and avoiding link congestion. In our design, the centralized SDN controller only pre-computes information needed by the switches during the update execution. This information is distributed to the switches, which use partial knowledge and direct message passing to efficiently realize the update. This separation of concerns has the key benefit of improving update performance as the communication and computation bottlenecks at the controller are removed. Our evaluations via network emulations and large-scale simulations demonstrate the efficiency of ez-Segway, which compared to a centralized approach, improves network update times by up to 45% and 57% at the median and the 99th percentile, respectively. A deployment of a system prototype in a real OpenFlow switch and an implementation in P4 demonstrate the feasibility and low overhead of implementing simple network update functionality within switches.

  8. Factors associated with secondhand smoke exposure in different settings: Results from the German Health Update (GEDA) 2012.

    Science.gov (United States)

    Fischer, Florian; Kraemer, Alexander

    2016-04-14

    The ubiquity of secondhand smoke (SHS) exposure at home or in private establishments, workplaces and public areas poses several challenges for the reduction of SHS exposure. This study aimed to describe the prevalence of SHS exposure in Germany and key factors associated with exposure. Results were also differentiated by place of exposure. A secondary data analysis based on the public use file of the German Health Update 2012 was conducted (n = 13,933). Only non-smokers were included in the analysis. In a multivariable logistic regression model the factors associated with SHS exposure were calculated. In addition, a further set of multivariable logistic regressions were calculated for factors associated with the place of SHS exposure (workplace, at home, bars/discotheques, restaurants, at the house of a friend). More than a quarter of non-smoking study participants were exposed to SHS. The main area of exposure was the workplace (40.9 %). The multivariable logistic regression indicated young age as the most important factor associated with SHS exposure. The odds for SHS exposure was higher in men than in women. The likelihood of SHS exposure decreased with higher education. SHS exposure and the associated factors varied between different places of exposure. Despite several actions to protect non-smokers which were implemented in Germany during the past years, SHS exposure still remains a relevant risk factor at a population level. According to the results of this study, particularly the workplace and other public places such as bars and discotheques have to be taken into account for the development of strategies to reduce SHS exposure.

  9. PfEMP1 – A Parasite Protein Family of Key Importance in Plasmodium falciparum Malaria Immunity and Pathogenesis

    DEFF Research Database (Denmark)

    Hviid, Lars; Jensen, Anja T R

    2015-01-01

    to be a central element in the pathogenesis of the disease. It is mediated by the interaction of parasite ligands on the erythrocyte surface and a range of host receptor molecules in many organs and tissues. Among several proteins and protein families implicated in this process, the P. falciparum erythrocyte...... membrane protein 1 (PfEMP1) family of high-molecular weight and highly variable antigens appears to be the most prominent. In this chapter, we aim to provide a systematic overview of the current knowledge about these proteins, their structure, their function, how they are presented on the erythrocyte...

  10. Updating Recursive XML Views of Relations

    DEFF Research Database (Denmark)

    Choi, Byron; Cong, Gao; Fan, Wenfei

    2009-01-01

    This paper investigates the view update problem for XML views published from relational data. We consider XML views defined in terms of mappings directed by possibly recursive DTDs compressed into DAGs and stored in relations. We provide new techniques to efficiently support XML view updates...... specified in terms of XPath expressions with recursion and complex filters. The interaction between XPath recursion and DAG compression of XML views makes the analysis of the XML view update problem rather intriguing. Furthermore, many issues are still open even for relational view updates, and need...... to be explored. In response to these, on the XML side, we revise the notion of side effects and update semantics based on the semantics of XML views, and present effecient algorithms to translate XML updates to relational view updates. On the relational side, we propose a mild condition on SPJ views, and show...

  11. Dissociating Working Memory Updating and Automatic Updating: The Reference-Back Paradigm

    Science.gov (United States)

    Rac-Lubashevsky, Rachel; Kessler, Yoav

    2016-01-01

    Working memory (WM) updating is a controlled process through which relevant information in the environment is selected to enter the gate to WM and substitute its contents. We suggest that there is also an automatic form of updating, which influences performance in many tasks and is primarily manifested in reaction time sequential effects. The goal…

  12. PF-WFS Shell Inspection Update December 2016

    Energy Technology Data Exchange (ETDEWEB)

    Vigil, Anthony Eugene [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Ledoux, Reina Rebecca [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Gonzales, Antonio R. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Montano, Joshua Daniel [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Savage, Lowell Curtis [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Randles, Wayne Alfred [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-01-26

    Since the last project update in FY16:Q2, PF-WFS personnel have advanced in understanding of shell inspection on Coordinate Measuring Machines {CMM} and refined the PF-WFS process to the point it was decided to convert shell inspection from the Sheffield #1 gage to Lietz CM Ms. As a part of introspection on the quality of this process many sets of data have been reviewed and analyzed. This analysis included Sheffield to CMM comparisons, CMM inspection repeatability, fixturing differences, quality check development, probing approach changes. This update report will touch on these improvements that have built the confidence in this process to mainstream it inspecting shells. In addition to the CMM programming advancements, the continuation in refinement of input and outputs for the CMM program has created an archiving scheme, input spline files, an output metafile, and inspection report package. This project will continue to mature. Part designs may require program modifications to accommodate "new to this process" part designs. Technology limitations tied to security and performance are requiring possible changes to computer configurations to support an automated process.

  13. Predictive Active Set Selection Methods for Gaussian Processes

    DEFF Research Database (Denmark)

    Henao, Ricardo; Winther, Ole

    2012-01-01

    We propose an active set selection framework for Gaussian process classification for cases when the dataset is large enough to render its inference prohibitive. Our scheme consists of a two step alternating procedure of active set update rules and hyperparameter optimization based upon marginal...... high impact to the classifier decision process while removing those that are less relevant. We introduce two active set rules based on different criteria, the first one prefers a model with interpretable active set parameters whereas the second puts computational complexity first, thus a model...... with active set parameters that directly control its complexity. We also provide both theoretical and empirical support for our active set selection strategy being a good approximation of a full Gaussian process classifier. Our extensive experiments show that our approach can compete with state...

  14. Updating systematic reviews: an international survey.

    Directory of Open Access Journals (Sweden)

    Chantelle Garritty

    Full Text Available BACKGROUND: Systematic reviews (SRs should be up to date to maintain their importance in informing healthcare policy and practice. However, little guidance is available about when and how to update SRs. Moreover, the updating policies and practices of organizations that commission or produce SRs are unclear. METHODOLOGY/PRINCIPAL FINDINGS: The objective was to describe the updating practices and policies of agencies that sponsor or conduct SRs. An Internet-based survey was administered to a purposive non-random sample of 195 healthcare organizations within the international SR community. Survey results were analyzed using descriptive statistics. The completed response rate was 58% (n = 114 from across 26 countries with 70% (75/107 of participants identified as producers of SRs. Among responders, 79% (84/107 characterized the importance of updating as high or very-high and 57% (60/106 of organizations reported to have a formal policy for updating. However, only 29% (35/106 of organizations made reference to a written policy document. Several groups (62/105; 59% reported updating practices as irregular, and over half (53/103 of organizational respondents estimated that more than 50% of their respective SRs were likely out of date. Authors of the original SR (42/106; 40% were most often deemed responsible for ensuring SRs were current. Barriers to updating included resource constraints, reviewer motivation, lack of academic credit, and limited publishing formats. Most respondents (70/100; 70% indicated that they supported centralization of updating efforts across institutions or agencies. Furthermore, 84% (83/99 of respondents indicated they favoured the development of a central registry of SRs, analogous to efforts within the clinical trials community. CONCLUSIONS/SIGNIFICANCE: Most organizations that sponsor and/or carry out SRs consider updating important. Despite this recognition, updating practices are not regular, and many organizations lack

  15. Using lean methodology to improve efficiency of electronic order set maintenance in the hospital.

    Science.gov (United States)

    Idemoto, Lori; Williams, Barbara; Blackmore, Craig

    2016-01-01

    Order sets, a series of orders focused around a diagnosis, condition, or treatment, can reinforce best practice, help eliminate outdated practice, and provide clinical guidance. However, order sets require regular updates as evidence and care processes change. We undertook a quality improvement intervention applying lean methodology to create a systematic process for order set review and maintenance. Root cause analysis revealed challenges with unclear prioritization of requests, lack of coordination between teams, and lack of communication between producers and requestors of order sets. In March of 2014, we implemented a systematic, cyclical order set review process, with a set schedule, defined responsibilities for various stakeholders, formal meetings and communication between stakeholders, and transparency of the process. We first identified and deactivated 89 order sets which were infrequently used. Between March and August 2014, 142 order sets went through the new review process. Processing time for the build duration of order sets decreased from a mean of 79.6 to 43.2 days (pLean production principles to the order set review process resulted in significant improvement in processing time and increased quality of orders. As use of order sets and other forms of clinical decision support increase, regular evidence and process updates become more critical.

  16. Alpha power gates relevant information during working memory updating.

    Science.gov (United States)

    Manza, Peter; Hau, Chui Luen Vera; Leung, Hoi-Chung

    2014-04-23

    Human working memory (WM) is inherently limited, so we must filter out irrelevant information in our environment or our mind while retaining limited important relevant contents. Previous work suggests that neural oscillations in the alpha band (8-14 Hz) play an important role in inhibiting incoming distracting information during attention and selective encoding tasks. However, whether alpha power is involved in inhibiting no-longer-relevant content or in representing relevant WM content is still debated. To clarify this issue, we manipulated the amount of relevant/irrelevant information using a task requiring spatial WM updating while measuring neural oscillatory activity via EEG and localized current sources across the scalp using a surface Laplacian transform. An initial memory set of two, four, or six spatial locations was to be memorized over a delay until an updating cue was presented indicating that only one or three locations remained relevant for a subsequent recognition test. Alpha amplitude varied with memory maintenance and updating demands among a cluster of left frontocentral electrodes. Greater postcue alpha power was associated with the high relevant load conditions (six and four dots cued to reduce to three relevant) relative to the lower load conditions (four and two dots reduced to one). Across subjects, this difference in alpha power was correlated with condition differences in performance accuracy. In contrast, no significant effects of irrelevant load were observed. These findings demonstrate that, during WM updating, alpha power reflects maintenance of relevant memory contents rather than suppression of no-longer-relevant memory traces.

  17. [Purity Detection Model Update of Maize Seeds Based on Active Learning].

    Science.gov (United States)

    Tang, Jin-ya; Huang, Min; Zhu, Qi-bing

    2015-08-01

    Seed purity reflects the degree of seed varieties in typical consistent characteristics, so it is great important to improve the reliability and accuracy of seed purity detection to guarantee the quality of seeds. Hyperspectral imaging can reflect the internal and external characteristics of seeds at the same time, which has been widely used in nondestructive detection of agricultural products. The essence of nondestructive detection of agricultural products using hyperspectral imaging technique is to establish the mathematical model between the spectral information and the quality of agricultural products. Since the spectral information is easily affected by the sample growth environment, the stability and generalization of model would weaken when the test samples harvested from different origin and year. Active learning algorithm was investigated to add representative samples to expand the sample space for the original model, so as to implement the rapid update of the model's ability. Random selection (RS) and Kennard-Stone algorithm (KS) were performed to compare the model update effect with active learning algorithm. The experimental results indicated that in the division of different proportion of sample set (1:1, 3:1, 4:1), the updated purity detection model for maize seeds from 2010 year which was added 40 samples selected by active learning algorithm from 2011 year increased the prediction accuracy for 2011 new samples from 47%, 33.75%, 49% to 98.89%, 98.33%, 98.33%. For the updated purity detection model of 2011 year, its prediction accuracy for 2010 new samples increased by 50.83%, 54.58%, 53.75% to 94.57%, 94.02%, 94.57% after adding 56 new samples from 2010 year. Meanwhile the effect of model updated by active learning algorithm was better than that of RS and KS. Therefore, the update for purity detection model of maize seeds is feasible by active learning algorithm.

  18. Update of the Used Fuel Dispositon Campaign Implementation Plan

    Energy Technology Data Exchange (ETDEWEB)

    McMahon, Kevin A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Bragg-Sitton, Shannon [Idaho National Lab. (INL), Idaho Falls, ID (United States); Mackinnon, Robert James [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Saltzstein, Sylvia J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Sorenson, Ken B. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Swift, Peter N. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Birkholzer, Jens T. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2014-10-01

    This Update to the Used Fuel Disposition Campaign Implementation Plan provides summary level detail describing how the Used Fuel Disposition Campaign (UFDC) supports achievement of the overarching mission and objectives of the Department of Energy Office of Nuclear Energy Fuel Cycle Technologies Program, building on work completed in this area since 2009. This implementation plan begins with the assumption of target dates that are set out in the January 2013 DOE Strategy for the Management and Disposal of Used Nuclear Fuel and High-Level Radioactive Waste (http://energy.gov/downloads/strategy-management-and-disposal-used-nuclearfuel- and-high-level-radioactive-waste). These target dates and goals are summarized in section III. This implementation plan will be maintained as a living document and will be updated as needed in response to available funding and progress in the Used Fuel Disposition Campaign and the Fuel Cycle Technologies Program.

  19. Quantifying Update Effects in Citizen-Oriented Software

    Directory of Open Access Journals (Sweden)

    Ion Ivan

    2009-02-01

    Full Text Available Defining citizen-oriented software. Detailing technical issues regarding update process in this kind of software. Presenting different effects triggered by types of update. Building model for update costs estimation, including producer-side and consumer-side effects. Analyzing model applicability on INVMAT – large scale matrix inversion software. Proposing a model for update effects estimation. Specifying ways for softening effects of inaccurate updates.

  20. Are Forecast Updates Progressive?

    NARCIS (Netherlands)

    C-L. Chang (Chia-Lin); Ph.H.B.F. Franses (Philip Hans); M.J. McAleer (Michael)

    2010-01-01

    textabstractMacro-economic forecasts typically involve both a model component, which is replicable, as well as intuition, which is non-replicable. Intuition is expert knowledge possessed by a forecaster. If forecast updates are progressive, forecast updates should become more accurate, on average,

  1. Determinantes multidimensionales en la calidad percibida del empleo. Evidencia empírica para España

    Directory of Open Access Journals (Sweden)

    Díaz-Chao, Ángel

    2015-04-01

    Full Text Available Through a representative sample of 8.755 employees in 2010, and using a structural equations model (SEM, this article analyzes empirically the multidimensional determinants (direct effects of the perceived work quality in Spain. The research concludes that the perceived work quality combines a broad set of explanatory dimensions that are linked with de workplace itself (intrinsic work quality, organization, access and inclusion, and compensations, but also with their environment and labor relations (social relations, work intensity, skills and training, and health and safety. Therefore, the public employment policies for ending the economic crisis should not only address the quality or workplace, but also meet the dimensions related to their environment and labor relations.A través de una muestra representativa para 8.755 empleados asalariados en 2010, y utilizando un sistema de ecuaciones estructurales, este artículo analiza empíricamente los determinantes multidimensionales (efectos directos de la calidad percibida del empleo en España. La investigación concluye que la calidad del empleo combina un amplio conjunto de dimensiones explicativas que están vinculadas con el propio puesto de trabajo (calidad intrínseca, organización, inclusión y acceso y compensación, pero también con su entorno y las relaciones laborales (relaciones sociales, intensidad del empleo, formación, y salud y seguridad en el trabajo. Por consiguiente, las políticas públicas de empleo para la salida de la crisis no solo deberían abordar la calidad del puesto de trabajo, sino también atender a las dimensiones vinculadas con su entorno y las relaciones laborales.

  2. Construction and updating of a public events questionnaire for repeated measures longitudinal studies

    Directory of Open Access Journals (Sweden)

    Martha eNoone

    2014-03-01

    Full Text Available Impairments of retrospective memory and cases of retrograde amnesia are often seen in clinical settings. A measure of the proportion of memories retained over a specified time can be useful in clinical situations and public events questionnaires may be valuable in this respect. However, consistency of retention of public events memory has rarely been studied in the same participants. In addition, when used in a research context, public events questionnaires require updating to ensure questions are of equivalent age with respect to when the test is taken. This paper describes an approach to constructing and updating a Public Events Questionnaire (PEQ for use with a sample that is recruited and followed-up over a long time-period. Internal consistency, parallel-form reliability, test-retest reliability and secondary validity analyses were examined for three versions of the PEQ that were updated every six months. Versions 2 and 3 of the questionnaire were reliable across and within versions and for recall and recognition. Change over time was comparable across each version of the PEQ. These results show that PEQs can be regularly updated in a standardised fashion to allow use throughout studies with long recruitment periods.

  3. Construction and updating of a public events questionnaire for repeated measures longitudinal studies.

    Science.gov (United States)

    Noone, Martha; Semkovska, Maria; Carton, Mary; Dunne, Ross; Horgan, John-Paul; O'Kane, Breige; McLoughlin, Declan M

    2014-01-01

    Impairments of retrospective memory and cases of retrograde amnesia are often seen in clinical settings. A measure of the proportion of memories retained over a specified time can be useful in clinical situations and public events questionnaires may be valuable in this respect. However, consistency of retention of public events memory has rarely been studied in the same participants. In addition, when used in a research context, public events questionnaires require updating to ensure questions are of equivalent age with respect to when the test is taken. This paper describes an approach to constructing and updating a Public Events Questionnaire (PEQ) for use with a sample that is recruited and followed-up over a long time-period. Internal consistency, parallel-form reliability, test-retest reliability, and secondary validity analyses were examined for three versions of the PEQ that were updated every 6 months. Versions 2 and 3 of the questionnaire were reliable across and within versions and for recall and recognition. Change over time was comparable across each version of the PEQ. These results show that PEQs can be regularly updated in a standardized fashion to allow use throughout studies with long recruitment periods.

  4. Updating of working memory: lingering bindings.

    Science.gov (United States)

    Oberauer, Klaus; Vockenberg, Kerstin

    2009-05-01

    Three experiments investigated proactive interference and proactive facilitation in a memory-updating paradigm. Participants remembered several letters or spatial patterns, distinguished by their spatial positions, and updated them by new stimuli up to 20 times per trial. Self-paced updating times were shorter when an item previously remembered and then replaced reappeared in the same location than when it reappeared in a different location. This effect demonstrates residual memory for no-longer-relevant bindings of items to locations. The effect increased with the number of items to be remembered. With one exception, updating times did not increase, and recall of final values did not decrease, over successive updating steps, thus providing little evidence for proactive interference building up cumulatively.

  5. A rapid learning and dynamic stepwise updating algorithm for flat neural networks and the application to time-series prediction.

    Science.gov (United States)

    Chen, C P; Wan, J Z

    1999-01-01

    A fast learning algorithm is proposed to find an optimal weights of the flat neural networks (especially, the functional-link network). Although the flat networks are used for nonlinear function approximation, they can be formulated as linear systems. Thus, the weights of the networks can be solved easily using a linear least-square method. This formulation makes it easier to update the weights instantly for both a new added pattern and a new added enhancement node. A dynamic stepwise updating algorithm is proposed to update the weights of the system on-the-fly. The model is tested on several time-series data including an infrared laser data set, a chaotic time-series, a monthly flour price data set, and a nonlinear system identification problem. The simulation results are compared to existing models in which more complex architectures and more costly training are needed. The results indicate that the proposed model is very attractive to real-time processes.

  6. Update and revision of WHO air quality guidelines for Europe

    Energy Technology Data Exchange (ETDEWEB)

    Younes, M. [WHO European Centre for Environment and Health, Bilthoven (Netherlands). Bilthoven Div.

    1995-12-31

    The WHO Air Quality Guidelines for Europe (AQG), published in 1987, have provided a uniform basis for the development of strategies for the control of air pollution, and have contributed to the maintenance and improvement of public health in several countries. The aim of the guidelines is to provide a basis for protecting public health from adverse effects of air pollutants, and for eliminating or reducing to a minimum, those contaminants that are known or likely to be hazardous to human health and wellbeing. Since the publication of the first edition of the AQG, new scientific data in the fields of air pollution toxicology and epidemiology have accumulated and new developments in risk assessment methodologies have taken place, requiring updating and/or revision of the existing guidelines. This fact was recognized during the preparation of the initial work plan of the European Centre for Environment and Health, and it was recommended that the Centre undertake any necessary amendments and extensions to the Air Quality Guidelines. The updating procedure is being carried out in cooperation with the International Programme on Chemical Safety (IPCS) and the Commission of the European Communities (CEC) and will be implemented through working group meetings which require the preparation of working documents on specific air pollutants or mixtures and a final consultation to discuss the updated document.It was initiated by a Planning Meeting which was organized in January 1993. The purpose of the planning meeting was to set the framework for the updating and revision process, in particular to discuss the scope and purpose, the contents and the format of the revised AQG publication, to define the details of and the time schedule for the updating process and to identify the working groups needed and their way of operation. (author)

  7. Update and revision of WHO air quality guidelines for Europe

    Energy Technology Data Exchange (ETDEWEB)

    Younes, M [WHO European Centre for Environment and Health, Bilthoven (Netherlands). Bilthoven Div.

    1996-12-31

    The WHO Air Quality Guidelines for Europe (AQG), published in 1987, have provided a uniform basis for the development of strategies for the control of air pollution, and have contributed to the maintenance and improvement of public health in several countries. The aim of the guidelines is to provide a basis for protecting public health from adverse effects of air pollutants, and for eliminating or reducing to a minimum, those contaminants that are known or likely to be hazardous to human health and wellbeing. Since the publication of the first edition of the AQG, new scientific data in the fields of air pollution toxicology and epidemiology have accumulated and new developments in risk assessment methodologies have taken place, requiring updating and/or revision of the existing guidelines. This fact was recognized during the preparation of the initial work plan of the European Centre for Environment and Health, and it was recommended that the Centre undertake any necessary amendments and extensions to the Air Quality Guidelines. The updating procedure is being carried out in cooperation with the International Programme on Chemical Safety (IPCS) and the Commission of the European Communities (CEC) and will be implemented through working group meetings which require the preparation of working documents on specific air pollutants or mixtures and a final consultation to discuss the updated document.It was initiated by a Planning Meeting which was organized in January 1993. The purpose of the planning meeting was to set the framework for the updating and revision process, in particular to discuss the scope and purpose, the contents and the format of the revised AQG publication, to define the details of and the time schedule for the updating process and to identify the working groups needed and their way of operation. (author)

  8. How do we update faces? Effects of gaze direction and facial expressions on working memory updating

    Directory of Open Access Journals (Sweden)

    Caterina eArtuso

    2012-09-01

    Full Text Available The aim of the study was to investigate how the biological binding between different facial dimensions, and their social and communicative relevance, may impact updating processes in working memory (WM. We focused on WM updating because it plays a key role in ongoing processing. Gaze direction and facial expression are crucial and changeable components of face processing. Direct gaze enhances the processing of approach-oriented facial emotional expressions (e.g. joy, while averted gaze enhances the processing of avoidance-oriented facial emotional expressions (e.g. fear. Thus, the way in which these two facial dimensions are combined communicates to the observer important behavioral and social information. Updating of these two facial dimensions and their bindings has not been investigated before, despite the fact that they provide a piece of social information essential for building and maintaining an internal ongoing representation of our social environment. In Experiment 1 we created a task in which the binding between gaze direction and facial expression was manipulated: high binding conditions (e.g. joy-direct gaze were compared to low binding conditions (e.g. joy-averted gaze. Participants had to study and update continuously a number of faces, displaying different bindings between the two dimensions. In Experiment 2 we tested whether updating was affected by the social and communicative value of the facial dimension binding; to this end, we manipulated bindings between eye and hair color, two less communicative facial dimensions. Two new results emerged. First, faster response times were found in updating combinations of facial dimensions highly bound together. Second, our data showed that the ease of the ongoing updating processing varied depending on the communicative meaning of the binding that had to be updated. The results are discussed with reference to the role of WM updating in social cognition and appraisal processes.

  9. How do we update faces? Effects of gaze direction and facial expressions on working memory updating.

    Science.gov (United States)

    Artuso, Caterina; Palladino, Paola; Ricciardelli, Paola

    2012-01-01

    The aim of the study was to investigate how the biological binding between different facial dimensions, and their social and communicative relevance, may impact updating processes in working memory (WM). We focused on WM updating because it plays a key role in ongoing processing. Gaze direction and facial expression are crucial and changeable components of face processing. Direct gaze enhances the processing of approach-oriented facial emotional expressions (e.g., joy), while averted gaze enhances the processing of avoidance-oriented facial emotional expressions (e.g., fear). Thus, the way in which these two facial dimensions are combined communicates to the observer important behavioral and social information. Updating of these two facial dimensions and their bindings has not been investigated before, despite the fact that they provide a piece of social information essential for building and maintaining an internal ongoing representation of our social environment. In Experiment 1 we created a task in which the binding between gaze direction and facial expression was manipulated: high binding conditions (e.g., joy-direct gaze) were compared to low binding conditions (e.g., joy-averted gaze). Participants had to study and update continuously a number of faces, displaying different bindings between the two dimensions. In Experiment 2 we tested whether updating was affected by the social and communicative value of the facial dimension binding; to this end, we manipulated bindings between eye and hair color, two less communicative facial dimensions. Two new results emerged. First, faster response times were found in updating combinations of facial dimensions highly bound together. Second, our data showed that the ease of the ongoing updating processing varied depending on the communicative meaning of the binding that had to be updated. The results are discussed with reference to the role of WM updating in social cognition and appraisal processes.

  10. Large Deployable Reflector (LDR) feasibility study update

    Science.gov (United States)

    Alff, W. H.; Banderman, L. W.

    1983-01-01

    In 1982 a workshop was held to refine the science rationale for large deployable reflectors (LDR) and develop technology requirements that support the science rationale. At the end of the workshop, a set of LDR consensus systems requirements was established. The subject study was undertaken to update the initial LDR study using the new systems requirements. The study included mirror materials selection and configuration, thermal analysis, structural concept definition and analysis, dynamic control analysis and recommendations for further study. The primary emphasis was on the dynamic controls requirements and the sophistication of the controls system needed to meet LDR performance goals.

  11. Migrações internas: evolução teórica e algumas evidências empíricas para o caso brasileiro

    OpenAIRE

    Márcia Regina Gabardo Câmara

    1988-01-01

    The aim of this article is to show new light concerning internal migration in Brazil. Consequently a review of the specialized literature was necessary and here in are presented some empirical evidences concerning its recent development. O objetivo do presente artigo é jogar novas luzes sobre a migração interna no Brasil. Conseqüentemente, foi necessário revisar a literatura especializada e apresentar algumas evidências empíricas sobre o seu desenvolvimento recente

  12. Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genes

    DEFF Research Database (Denmark)

    Jensen, Anja T R; Magistrado, Pamela; Sharp, Sarah

    2004-01-01

    Parasite-encoded variant surface antigens (VSAs) like the var gene-encoded Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family are responsible for antigenic variation and infected red blood cell (RBC) cytoadhesion in P. falciparum malaria. Parasites causing severe malaria in noni...... genes, such as PFD1235w/MAL7P1.1, appear to be involved in the pathogenesis of severe disease and are thus attractive candidates for a vaccine against life-threatening P. falciparum malaria....

  13. Contramedidas em segurança da informação e vulnerabilidade cibernética: evidência empírica de empresas brasileiras

    Directory of Open Access Journals (Sweden)

    Igor Siqueira Cortez

    2013-12-01

    Full Text Available Recentemente, uma série de ataques cibernéticos a empresas e governos no Brasil e no exterior tornou público o potencial impacto econômico desse tipo de atividade, do ponto de vista tanto privado quanto público. Existe extensa literatura econômica - teórica e empírica - que avalia os incentivos para que as empresas adotem ou não medidas de segurança da informação. No presente estudo foi desenvolvida uma avaliação empírica desse fenômeno no Brasil. Modelos logit e probit ordenado foram desenvolvidos como forma de avaliar os efeitos sobre a probabilidade de ocorrência de problemas de segurança da informação, levando-se em conta as características das firmas, inclusive as medidas de segurança de informação. Os resultados apontam para uma relação positiva entre as medidas de segurança da informação e a probabilidade de identificar a ocorrência de problemas cibernéticos, sugerindo que a sofisticação dessas medidas de proteção aumenta a probabilidade de identificação dos problemas.

  14. Revisi?n de literatura emp?rica acerca de la relaci?n entre depresi?n y apoyo familiar en personas transg?nero

    OpenAIRE

    Ruiz Cortes, Estefany Tatiana

    2017-01-01

    Se realiz? una revisi?n de diferentes trabajos e investigaci?n emp?rica sobre sobre el concepto de g?nero e identidad de g?nero y la conceptualizaci?n del transgenerismo como fen?meno buscando una aproximaci?n de los factores que intervienen en el proceso de socializaci?n y desarrollo psicosocial de las personas transg?nero. La constante discriminaci?n, estigmatizaci?n y segregaci?n social hacen que las personas trans sean vulnerables y que lleguen a presentar niveles de ansiedad, depresi?n y...

  15. Parameterized Analysis of Paging and List Update Algorithms

    DEFF Research Database (Denmark)

    Dorrigiv, Reza; Ehmsen, Martin R.; López-Ortiz, Alejandro

    2015-01-01

    that a larger cache leads to a better performance. We also apply the parameterized analysis framework to list update and show that certain randomized algorithms which are superior to MTF in the classical model are not so in the parameterized case, which matches experimental results....... set model and express the performance of well known algorithms in terms of this parameter. This explicitly introduces parameterized-style analysis to online algorithms. The idea is that rather than normalizing the performance of an online algorithm by an (optimal) offline algorithm, we explicitly...... express the behavior of the algorithm in terms of two more natural parameters: the size of the cache and Denning’s working set measure. This technique creates a performance hierarchy of paging algorithms which better reflects their experimentally observed relative strengths. It also reflects the intuition...

  16. Relationships between the use of Embden Meyerhof pathway (EMP) or Phosphoketolase pathway (PKP) and lactate production capabilities of diverse Lactobacillus reuteri strains.

    Science.gov (United States)

    Burgé, Grégoire; Saulou-Bérion, Claire; Moussa, Marwen; Allais, Florent; Athes, Violaine; Spinnler, Henry-Eric

    2015-10-01

    The aims of this study is to compare the growth and glucose metabolism of three Lactobacillus reuteri strains (i.e. DSM 20016, DSM 17938, and ATCC 53608) which are lactic acid bacteria of interest used for diverse applications such as probiotics implying the production of biomass, or for the production of valuable chemicals (3-hydroxypropionaldehyde, 3-hydroxypropionic acid, 1,3-propanediol). However, the physiological diversity inside the species, even for basic metabolisms, like its capacity of acidification or glucose metabolism, has not been studied yet. In the present work, the growth and metabolism of three strains representative of the species diversity have been studied in batch mode. The strains were compared through characterization of growth kinetics and evaluation of acidification kinetics, substrate consumption and product formation. The results showed significant differences between the three strains which may be explained, at least in part, by variations in the distribution of carbon source between two glycolytic pathways during the bacterial growth: the phosphoketolase or heterolactic pathway (PKP) and the Embden-Meyerhof pathway (EMP). It was also shown that, in the context of obtaining a large amount of biomass, DSM 20016 and DSM 17938 strains were the most effective in terms of growth kinetics. The DSM 17938 strain, which shows the more significant metabolic shift from EMP to PKP when the pH decreases, is more effective for lactate production.

  17. Intraoperative magnetic resonance imaging to update interactive navigation in neurosurgery: method and preliminary experience.

    Science.gov (United States)

    Wirtz, C R; Bonsanto, M M; Knauth, M; Tronnier, V M; Albert, F K; Staubert, A; Kunze, S

    1997-01-01

    We report on the first successful intraoperative update of interactive image guidance based on an intraoperatively acquired magnetic resonance imaging (MRI) date set. To date, intraoperative imaging methods such as ultrasound, computerized tomography (CT), or MRI have not been successfully used to update interactive navigation. We developed a method of imaging patients intraoperatively with the surgical field exposed in an MRI scanner (Magnetom Open; Siemens Corp., Erlangen, Germany). In 12 patients, intraoperatively acquired 3D data sets were used for successful recalibration of neuronavigation, accounting for any anatomical changes caused by surgical manipulations. The MKM Microscope (Zeiss Corp., Oberkochen, Germany) was used as navigational system. With implantable fiducial markers, an accuracy of 0.84 +/- 0.4 mm for intraoperative reregistration was achieved. Residual tumor detected on MRI was consequently resected using navigation with the intraoperative data. No adverse effects were observed from intraoperative imaging or the use of navigation with intraoperative images, demonstrating the feasibility of recalibrating navigation with intraoperative MRI.

  18. Insect cells are superior to Escherichia coli in producing malaria proteins inducing IgG targeting PfEMP1 on infected erythrocytes

    Directory of Open Access Journals (Sweden)

    Joergensen Louise

    2010-11-01

    Full Text Available Abstract Background The PFD1235w Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1 antigen is associated with severe malaria in children and can be expressed on the surface of infected erythrocytes (IE adhering to ICAM1. However, the exact three-dimensional structure of this PfEMP1 and its surface-exposed epitopes are unknown. An insect cell and Escherichia coli based system was used to express single and double domains encoded by the pfd1235w var gene. The resulting recombinant proteins have been evaluated for yield and purity and their ability to induce rat antibodies, which react with the native PFD1235w PfEMP1 antigen expressed on 3D7PFD1235w-IE. Their recognition by human anti-malaria antibodies from previously infected Tanzanian donors was also analysed. Methods The recombinant proteins were run on SDS-PAGE and Western blots for quantification and size estimation. Insect cell and E. coli-produced recombinant proteins were coupled to a bead-based Luminex assay to measure the plasma antibody reactivity of 180 samples collected from Tanzanian individuals. The recombinant proteins used for immunization of rats and antisera were also tested by flow cytometry for their ability to surface label 3D7PFD1235w-IE. Results All seven pAcGP67A constructs were successfully expressed as recombinant protein in baculovirus-infected insect cells and subsequently produced to a purity of 60-97% and a yield of 2-15 mg/L. By comparison, only three of seven pET101/D-TOPO constructs expressed in the E. coli system could be produced at all with purity and yield ranging from 3-95% and 6-11 mg/L. All seven insect cell, but only two of the E. coli produced proteins induced antibodies reactive with native PFD1235w expressed on 3D7PFD1235w-IE. The recombinant proteins were recognized in an age- and transmission intensity-dependent manner by antibodies from 180 Tanzanian individuals in a bead-based Luminex assay. Conclusions The baculovirus based insect cell

  19. A Class of Manifold Regularized Multiplicative Update Algorithms for Image Clustering.

    Science.gov (United States)

    Yang, Shangming; Yi, Zhang; He, Xiaofei; Li, Xuelong

    2015-12-01

    Multiplicative update algorithms are important tools for information retrieval, image processing, and pattern recognition. However, when the graph regularization is added to the cost function, different classes of sample data may be mapped to the same subspace, which leads to the increase of data clustering error rate. In this paper, an improved nonnegative matrix factorization (NMF) cost function is introduced. Based on the cost function, a class of novel graph regularized NMF algorithms is developed, which results in a class of extended multiplicative update algorithms with manifold structure regularization. Analysis shows that in the learning, the proposed algorithms can efficiently minimize the rank of the data representation matrix. Theoretical results presented in this paper are confirmed by simulations. For different initializations and data sets, variation curves of cost functions and decomposition data are presented to show the convergence features of the proposed update rules. Basis images, reconstructed images, and clustering results are utilized to present the efficiency of the new algorithms. Last, the clustering accuracies of different algorithms are also investigated, which shows that the proposed algorithms can achieve state-of-the-art performance in applications of image clustering.

  20. Migrações internas: evolução teórica e algumas evidências empíricas para o caso brasileiro

    Directory of Open Access Journals (Sweden)

    Márcia Regina Gabardo Câmara

    1988-08-01

    Full Text Available The aim of this article is to show new light concerning internal migration in Brazil. Consequently a review of the specialized literature was necessary and here in are presented some empirical evidences concerning its recent development. O objetivo do presente artigo é jogar novas luzes sobre a migração interna no Brasil. Conseqüentemente, foi necessário revisar a literatura especializada e apresentar algumas evidências empíricas sobre o seu desenvolvimento recente

  1. Elementos teóricos para el análisis empírico de la demanda

    Directory of Open Access Journals (Sweden)

    Gustavo López,

    2001-07-01

    Full Text Available El presente artículo constituye una síntesis de la teoría de la demanda y su única pretensión es la de establecer el nexo –poco usual entre nosotros- entre esa teoría y sus aplicaciones, para lo cual es necesario destacar algunos aspectos particulares. Después de un breve repaso a los elementos teóricos básicos se detallan algunas características que debe cumplir una función de demanda para que resulte adecuada a los requerimientos teóricos, así como algunas restricciones resultantes de la propia ecuación presupuestal y que impone límites a los valores de las elasticidades. Por último, se presentan algunos aspectos de la dualidad en la teoría de la demanda que son especialmente útiles en el manejo empírico.

  2. Evolución y determinantes de las exportaciones industriales regionales: evidencia empírica para Colombia (1977-2002

    Directory of Open Access Journals (Sweden)

    Lotero Contreras Jorge

    2011-09-01

    Full Text Available
    Este artículo examina el impacto de las variables macroeconómicas, de la productividad y de la
    geografía sobre las exportaciones industriales colombianas entre 1977 y 2002, usando datos de la
    Encuesta Nacional Manufacturera y de Comercio Exterior del DANE. El estudio se centra en las
    exportaciones al mundo, a Estados Unidos y a la Comunidad Andina de Naciones-CAN. La
    estrategia empírica incluye análisis de datos de panel cuyos resultados sugieren que para los
    mercados considerados, la distancia, la productividad y la protección efectiva tienen un efecto
    apreciable –aunque diferenciado–, sobre el comportamiento de las exportaciones industriales

  3. Analysis of effects of updated decay and fission yield data on ORIGEN 2 results

    International Nuclear Information System (INIS)

    Daniel, P.R.

    1993-01-01

    Work has been performed to improve the accuracy of ORIGEN2 results by updating both the decay library and the fission yield data in the cross-section library. This effort was performed under the auspices of Oak Ridge National Laboratory (ORNL) to ensure that ORIGEN2 uses the most up-to-date data. The impact of the new data was then quantitatively evaluated by solving a set of standard light water reactor (LWR) problems solved with ORIGEN2. The ORIGEN code, developed at ORNL in the late 1960's, is a point depletion code used to determine the composition and characteristics of spent fuel. The results from calculations performed with the code often form the basis for the study and design of reprocessing plants, spent-fuel shipping casks, waste treatment systems, and disposal facilities. The decay data were updated using data from ENDF/B-VI; fission yield data were updated using data from ENDF/B-V. The impact of these new data was then evaluated

  4. ENDL Ti and V evaluation updates

    International Nuclear Information System (INIS)

    Brown, D; Hoffman, R; Kelley, K; Beck, B

    2005-01-01

    We need ''full'' evaluations for the isotopes of Ti and V found naturally. We mean ''full'' in the sense that we wish to have data suitable for transporting neutrons through the material. In particular, we focus on: (1) σ(E) for largest cross sections (n,elas), (n,n'), (n,2n), etc.; and (2) dσ(E)/d(Omega) for (n,elas), (n,n'[i]). For the data to be useful, we want the cross section sets and outgoing particle distributions to form a self-consistent set and to have good agreement with experimental data where possible. Also, if possible, we wish: P(E,E') for all outgoing particles; P(E, μ) for all outgoing particles; and adequate resonance region. In this note, we will summarize existing evaluations for Ti and V and present several strategies for updating all Ti and V isotopes for immediate insertion in ENDL and for eventual submission to ENDF/B-VII. We adopt one of these strategies and describe where the data is posted for customer use

  5. Updated clinical guidelines experience major reporting limitations

    Directory of Open Access Journals (Sweden)

    Robin W.M. Vernooij

    2017-10-01

    Full Text Available Abstract Background The Checklist for the Reporting of Updated Guidelines (CheckUp was recently developed. However, so far, no systematic assessment of the reporting of updated clinical guidelines (CGs exists. We aimed to examine (1 the completeness of reporting the updating process in CGs and (2 the inter-observer reliability of CheckUp. Methods We conducted a systematic assessment of the reporting of the updating process in a sample of updated CGs using CheckUp. We performed a systematic search to identify updated CGs published in 2015, developed by a professional society, reporting a systematic review of the evidence, and containing at least one recommendation. Three reviewers independently assessed the CGs with CheckUp (16 items. We calculated the median score per item, per domain, and overall, converting scores to a 10-point scale. Multiple linear regression analyses were used to identify differences according to country, type of organisation, scope, and health topic of updated CGs. We calculated the intraclass coefficient (ICC and 95% confidence interval (95% CI for domains and overall score. Results We included in total 60 updated CGs. The median domain score on a 10-point scale for presentation was 5.8 (range 1.7 to 10, for editorial independence 8.3 (range 3.3 to 10, and for methodology 5.7 (range 0 to 10. The median overall score on a 10-point scale was 6.3 (range 3.1 to 10. Presentation and justification items at recommendation level (respectively reported by 27 and 38% of the CGs and the methods used for the external review and implementing changes in practice were particularly poorly reported (both reported by 38% of the CGs. CGs developed by a European or international institution obtained a statistically significant higher overall score compared to North American or Asian institutions (p = 0.014. Finally, the agreement among the reviewers on the overall score was excellent (ICC 0.88, 95% CI 0.75 to 0.95. Conclusions The

  6. Update of the Mexican College of Rheumatology guidelines for the pharmacologic treatment of rheumatoid arthritis.

    Science.gov (United States)

    Cardiel, Mario H; Díaz-Borjón, Alejandro; Vázquez del Mercado Espinosa, Mónica; Gámez-Nava, Jorge Iván; Barile Fabris, Leonor A; Pacheco Tena, César; Silveira Torre, Luis H; Pascual Ramos, Virginia; Goycochea Robles, María Victoria; Aguilar Arreola, Jorge Enrique; González Díaz, Verónica; Alvarez Nemegyei, José; González-López, Laura del Carmen; Salazar Páramo, Mario; Portela Hernández, Margarita; Castro Colín, Zully; Xibillé Friedman, Daniel Xavier; Alvarez Hernández, Everardo; Casasola Vargas, Julio; Cortés Hernández, Miguel; Flores-Alvarado, Diana E; Martínez Martínez, Laura A; Vega-Morales, David; Flores-Suárez, Luis Felipe; Medrano Ramírez, Gabriel; Barrera Cruz, Antonio; García González, Adolfo; López López, Susana Marisela; Rosete Reyes, Alejandra; Espinosa Morales, Rolando

    2014-01-01

    The pharmacologic management of rheumatoid arthritis has progressed substantially over the past years. It is therefore desirable that existing information be periodically updated. There are several published international guidelines for the treatment of rheumatoid arthritis that hardly adapt to the Mexican health system because of its limited healthcare resources. Hence, it is imperative to unify the existing recommendations and to incorporate them to a set of clinical, updated recommendations; the Mexican College of Rheumatology developed these recommendations in order to offer an integral management approach of rheumatoid arthritis according to the resources of the Mexican health system. To review, update and improve the available evidence within clinical practice guidelines on the pharmacological management of rheumatoid arthritis and produce a set of recommendations adapted to the Mexican health system, according to evidence available through December 2012. The working group was composed of 30 trained and experienced rheumatologists with a high quality of clinical knowledge and judgment. Recommendations were based on the highest quality evidence from the previously established treatment guidelines, meta-analysis and controlled clinical trials for the adult population with rheumatoid arthritis. During the conformation of this document, each working group settled the existing evidence from the different topics according to their experience. Finally, all the evidence and decisions were unified into a single document, treatment algorithm and drug standardization tables. This update of the Mexican Guidelines for the Pharmacologic Treatment of Rheumatoid Arthritis provides the highest quality information available at the time the working group undertook this review and contextualizes its use for the complex Mexican health system. Copyright © 2013 Elsevier España, S.L. All rights reserved.

  7. Optimal updating magnitude in adaptive flat-distribution sampling.

    Science.gov (United States)

    Zhang, Cheng; Drake, Justin A; Ma, Jianpeng; Pettitt, B Montgomery

    2017-11-07

    We present a study on the optimization of the updating magnitude for a class of free energy methods based on flat-distribution sampling, including the Wang-Landau (WL) algorithm and metadynamics. These methods rely on adaptive construction of a bias potential that offsets the potential of mean force by histogram-based updates. The convergence of the bias potential can be improved by decreasing the updating magnitude with an optimal schedule. We show that while the asymptotically optimal schedule for the single-bin updating scheme (commonly used in the WL algorithm) is given by the known inverse-time formula, that for the Gaussian updating scheme (commonly used in metadynamics) is often more complex. We further show that the single-bin updating scheme is optimal for very long simulations, and it can be generalized to a class of bandpass updating schemes that are similarly optimal. These bandpass updating schemes target only a few long-range distribution modes and their optimal schedule is also given by the inverse-time formula. Constructed from orthogonal polynomials, the bandpass updating schemes generalize the WL and Langfeld-Lucini-Rago algorithms as an automatic parameter tuning scheme for umbrella sampling.

  8. Circular Updates

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Circular Updates are periodic sequentially numbered instructions to debriefing staff and observers informing them of changes or additions to scientific and specimen...

  9. Aprendizaje Cooperativo: Bases teóricas y hallazgos empíricos que explican su eficacia

    Directory of Open Access Journals (Sweden)

    Edurne Goikoetxea

    2002-01-01

    Full Text Available El aprendizaje cooperativo (AC es una de las formas de organizar la enseñanza con mayor respaldo teórico y empírico, y cada vez más empleada. Este trabajo revisa la teoría del contacto de Allport (1954/1962 para explicar por qué los métodos de AC tienen efectos positivos en las relaciones intergrupales e interétnicas. El modelo de Slavin (1984 se revisa para juzgar los elementos de una instrucción eficaz que logran ser satisfechos por el AC, dando lugar a efectos positivos en el rendimiento académico. Se describen, además, los nueve métodos de AC más investigados y se resumen los principales hallazgos sobre sus efectos, así como los mecanismos que explican dichos efectos, según los estudios de revisión y de meta-análisis

  10. Um estudo empírico de um sistema de reconhecimento facial utilizando o classificador KNN

    Directory of Open Access Journals (Sweden)

    Fabio Abrantes Diniz

    2016-06-01

    Full Text Available Neste artigo, apresenta-se um estudo empírico de otimização das taxas de acurácias resultantes de um sistema de reconhecimento facial baseado nas técnicas Eigenfaces e K-Nearest Neighbors. Foram investigadas as seguintes variáveis: imagens com três dimensões distintas, número de características (Eigenfaces, valores de k da técnica K-Nearest Neighbors e três medidas de distância (euclidiana, Manhattan e euclidiana normalizada. Os estudos foram importantes para entender empiricamente quais parâmetros são os mais relevantes para as técnicas analisadas e que resultam em melhores taxas de acurácias de reconhecimento facial. Os resultados dos experimentos comprovaram que as imagens com dimensões 12x9 pixels produzem as melhores taxas de acurácias de reconhecimento facial, combinando com a medida de distância euclidiana normalizada e um número de Eigenfaces igual a vinte.

  11. Important update of CERN Mail Services

    CERN Multimedia

    IT Department

    2009-01-01

    The CERN Mail Services are evolving. In the course of June and July 2009, all CERN mailboxes will be updated with a new infrastructure for hosting mailboxes, running Exchange 2007. This update is taking place in order to provide the capacity upgrade for the constantly growing volume of CERN mailboxes. It is also the opportunity to provide a number of improvements to CERN mailboxes: new and improved Outlook Web Access (the web interface used to access your mailbox from a web browser, also known as "webmail"), new features in the Out-of-Office auto-reply assistant, easier spam management... The update will preserve the mailbox configuration and no specific action is required by users. During the next weeks, each mailbox will be individually notified of the upcoming update the day before it takes place. We invite all users to carefully read this notification as it will contain the latest information for this update. The mailbox will be unavailable for a short time during the ni...

  12. The Updating of Geospatial Base Data

    Science.gov (United States)

    Alrajhi, Muhamad N.; Konecny, Gottfried

    2018-04-01

    Topopographic mapping issues concern the area coverage at different scales and their age. The age of the map is determined by the system of updating. The United Nations (UNGGIM) have attempted to track the global map coverage at various scale ranges, which has greatly improved in recent decades. However the poor state of updating of base maps is still a global problem. In Saudi Arabia large scale mapping is carried out for all urban, suburban and rural areas by aerial surveys. Updating is carried out by remapping every 5 to 10 years. Due to the rapid urban development this is not satisfactory, but faster update methods are forseen by use of high resolution satellite imagery and the improvement of object oriented geodatabase structures, which will permit to utilize various survey technologies to update the photogrammetry established geodatabases. The longterm goal is to create an geodata infrastructure, which exists in Great Britain or Germany.

  13. Complex Span versus Updating Tasks of Working Memory: The Gap Is Not that Deep

    Science.gov (United States)

    Schmiedek, Florian; Hildebrandt, Andrea; Lovden, Martin; Wilhelm, Oliver; Lindenberger, Ulman

    2009-01-01

    How to best measure working memory capacity is an issue of ongoing debate. Besides established complex span tasks, which combine short-term memory demands with generally unrelated secondary tasks, there exists a set of paradigms characterized by continuous and simultaneous updating of several items in working memory, such as the n-back, memory…

  14. Insect cells are superior to Escherichia coli in producing malaria proteins inducing IgG targeting PfEMP1 on infected erythrocytes

    DEFF Research Database (Denmark)

    Victor, Michala E; Bengtsson, Anja; Andersen, Gorm

    2010-01-01

    -exposed epitopes are unknown. An insect cell and Escherichia coli based system was used to express single and double domains encoded by the pfd1235w var gene. The resulting recombinant proteins have been evaluated for yield and purity and their ability to induce rat antibodies, which react with the native PFD1235w...... PfEMP1 antigen expressed on 3D7PFD1235w-IE. Their recognition by human anti-malaria antibodies from previously infected Tanzanian donors was also analysed....

  15. Updating optical pseudoinverse associative memories.

    Science.gov (United States)

    Telfer, B; Casasent, D

    1989-07-01

    Selected algorithms for adding to and deleting from optical pseudoinverse associative memories are presented and compared. New realizations of pseudoinverse updating methods using vector inner product matrix bordering and reduced-dimensionality Karhunen-Loeve approximations (which have been used for updating optical filters) are described in the context of associative memories. Greville's theorem is reviewed and compared with the Widrow-Hoff algorithm. Kohonen's gradient projection method is expressed in a different form suitable for optical implementation. The data matrix memory is also discussed for comparison purposes. Memory size, speed and ease of updating, and key vector requirements are the comparison criteria used.

  16. Parallelized FDTD simulation for flat-plate bounded wave EMP simulator with lumped terminator

    International Nuclear Information System (INIS)

    Zhu Xiangqin; Chen Weiqing; Chen Zaigao; Cai Libing; Wang Jianguo

    2013-01-01

    A parallelized finite-difference time-domain(FDTD) method for simulating the bounded wave electromagnetic pulse (EMP) simulator with lumped terminator and parallel plate is presented. The effects of several model-parameters on the simulator to the fields in the working volume are simulated and analyzed. The results show that if the width of the lower PEC plate is(or is bigger than)1.5 times that of the upper plate of working volume, the projection length of front transitional section does not have a significant effect on the rise-times of electric fields at the points near the front transitional section, and the rise-times of electric fields at the points near the working volume center decrease as the projection length increases, but the decrement of rise-time decreases. The rise-times of E z at all points also decrease as the lower PEC plate's width increases, but the decrements of rise-time decreases. If the projection length of the front transitional section is fixed, the good results can not be obtained by increasing or decreasing the height of the simulator only, however, which has an optimal value. (authors)

  17. Matrimonios mixtos intraeuropeos: un modelo empírico (Intra-European intermarriage: an empirical model

    Directory of Open Access Journals (Sweden)

    Alaminos Chica, Antonio Francisco

    2008-06-01

    Full Text Available Resumen: La heterogeneidad con la que nos encontramos al estudiar las parejas interculturales o mixtas, va más allá de las diferencias de origen sociocultural; interviene factores tales como el rol que cada individuo adopta dentro de la pareja (por ejemplo, quién contribuye más económicamente, el status, el nivel educativo, etc.. En este artículo se propone un modelo empírico que muestra el efecto de un conjunto de variables, que expresan circunstancias sociales, sobre la decisión de formar un matrimonio interculturalmente mixto. También las consecuencias en la vida social del individuo.Abstract: The intercultural marriages or mixed marriages depend upon several factor. Not only the different cultural origin. Other determinants like the role of the partner (i.e. economic contribution, status, educational level, etc. or the type of the family (modern, traditional, etc. influence the outcomes. This paper contains a proposal of empirical model for study the intra-European mixed marriages.

  18. Level set methods for inverse scattering—some recent developments

    International Nuclear Information System (INIS)

    Dorn, Oliver; Lesselier, Dominique

    2009-01-01

    We give an update on recent techniques which use a level set representation of shapes for solving inverse scattering problems, completing in that matter the exposition made in (Dorn and Lesselier 2006 Inverse Problems 22 R67) and (Dorn and Lesselier 2007 Deformable Models (New York: Springer) pp 61–90), and bringing it closer to the current state of the art

  19. Analysis of Stress Updates in the Material-point Method

    DEFF Research Database (Denmark)

    Andersen, Søren; Andersen, Lars

    2009-01-01

    The material-point method (MPM) is a new numerical method for analysis of large strain engineering problems. The MPM applies a dual formulation, where the state of the problem (mass, stress, strain, velocity etc.) is tracked using a finite set of material points while the governing equations...... are solved on a background computational grid. Several references state, that one of the main advantages of the material-point method is the easy application of complicated material behaviour as the constitutive response is updated individually for each material point. However, as discussed here, the MPM way...

  20. Preconcepciones de ciencia y tecnología en los profesores de bachillerato: un estudio empírico en el estado de Guanajuato

    OpenAIRE

    Rebollo León, Jorge Luis

    2008-01-01

    En este artículo se presenta un estudio empírico con profesores que enseñan ciencias naturales a nivel Bachillerato. Actualmente muchos profesores mantienen una imagen deformada de lo que es la ciencia y la tecnología. Algunos la conciben como un conocimiento acabado e infalible, otros como una actividad a-histórica y a-problemática o bien hay quienes la conciben como un quehacer elitista y descontextualizado. El propósito de este estudio es conocer cuáles son las preconcepciones sobre la...

  1. Fatores de impacto na Atitude e na Intenção de uso do M-learning: um teste empírico

    OpenAIRE

    Kurtz, Renata; Macedo-Soares, T. Diana de; Ferreira, Jorge Brantes; Freitas, Angilberto Sabino de; Silva, Jorge Ferreira da

    2015-01-01

    Este artigo apresenta os resultados de uma pesquisa empírica em que se propõe um modelo para avaliar a atitude e a intenção de uso do mobile-learning(m-learning) por estudantes do ensino superior de um curso de administração baseado na teoria do flow, no Modelo de Aceitação de Tecnologia e na Teoria do Comportamento Planejado. A partir deste arcabouço teórico elaborou-se uma atividade prática envolvendo o uso de dispositivos com tecnologia móvel digital (celulares) em que se buscou aplicar o ...

  2. Facilitadores institucionales y sociales para la gobernanza local de los riesgos medioambientales. Análisis empírico con municipios chilenos

    Directory of Open Access Journals (Sweden)

    Patricio Valdivieso

    Full Text Available Resumen El contexto latinoamericano de exposición a riesgos medioambientales demanda un mayor entendimiento de los factores institucionales que tienen impacto en la gestión medioambiental local. Con el apoyo de métodos mixtos de investigación, este estudio examina hipótesis sobre relaciones entre factores políticos, institucionales, sociales y la gestión medioambiental municipal, en el contexto empírico de municipalidades chilenas. Los resultados sugieren que la combinación de factores políticos, arreglos y capacidades institucionales, y relaciones con la sociedad explican diferentes comportamientos municipales.

  3. The COG database: an updated version includes eukaryotes

    Directory of Open Access Journals (Sweden)

    Sverdlov Alexander V

    2003-09-01

    Full Text Available Abstract Background The availability of multiple, essentially complete genome sequences of prokaryotes and eukaryotes spurred both the demand and the opportunity for the construction of an evolutionary classification of genes from these genomes. Such a classification system based on orthologous relationships between genes appears to be a natural framework for comparative genomics and should facilitate both functional annotation of genomes and large-scale evolutionary studies. Results We describe here a major update of the previously developed system for delineation of Clusters of Orthologous Groups of proteins (COGs from the sequenced genomes of prokaryotes and unicellular eukaryotes and the construction of clusters of predicted orthologs for 7 eukaryotic genomes, which we named KOGs after eukaryotic orthologous groups. The COG collection currently consists of 138,458 proteins, which form 4873 COGs and comprise 75% of the 185,505 (predicted proteins encoded in 66 genomes of unicellular organisms. The eukaryotic orthologous groups (KOGs include proteins from 7 eukaryotic genomes: three animals (the nematode Caenorhabditis elegans, the fruit fly Drosophila melanogaster and Homo sapiens, one plant, Arabidopsis thaliana, two fungi (Saccharomyces cerevisiae and Schizosaccharomyces pombe, and the intracellular microsporidian parasite Encephalitozoon cuniculi. The current KOG set consists of 4852 clusters of orthologs, which include 59,838 proteins, or ~54% of the analyzed eukaryotic 110,655 gene products. Compared to the coverage of the prokaryotic genomes with COGs, a considerably smaller fraction of eukaryotic genes could be included into the KOGs; addition of new eukaryotic genomes is expected to result in substantial increase in the coverage of eukaryotic genomes with KOGs. Examination of the phyletic patterns of KOGs reveals a conserved core represented in all analyzed species and consisting of ~20% of the KOG set. This conserved portion of the

  4. 7. Mentor update and support: what do mentors need from an update?

    Science.gov (United States)

    Phillips, Mari; Marshall, Joyce

    2015-04-01

    Mentorship is the 14th series of 'Midwifery basics' targeted at practising midwives. The aim of these articles is to provide information to raise awareness of the impact of the work of midwives on women's experience, and encourage midwives to seek further information through a series of activities relating to the topic. In this seventh article Mari Phillips and Joyce Marshall consider some of the key issues related to mentor update and support and consider what mentors need from their annual update.

  5. Email Updates

    Science.gov (United States)

    ... of this page: https://medlineplus.gov/listserv.html Email Updates To use the sharing features on this ... view your email history or unsubscribe. Prevent MedlinePlus emails from being marked as "spam" or "junk" To ...

  6. Valence-Dependent Belief Updating: Computational Validation

    Directory of Open Access Journals (Sweden)

    Bojana Kuzmanovic

    2017-06-01

    Full Text Available People tend to update beliefs about their future outcomes in a valence-dependent way: they are likely to incorporate good news and to neglect bad news. However, belief formation is a complex process which depends not only on motivational factors such as the desire for favorable conclusions, but also on multiple cognitive variables such as prior beliefs, knowledge about personal vulnerabilities and resources, and the size of the probabilities and estimation errors. Thus, we applied computational modeling in order to test for valence-induced biases in updating while formally controlling for relevant cognitive factors. We compared biased and unbiased Bayesian models of belief updating, and specified alternative models based on reinforcement learning. The experiment consisted of 80 trials with 80 different adverse future life events. In each trial, participants estimated the base rate of one of these events and estimated their own risk of experiencing the event before and after being confronted with the actual base rate. Belief updates corresponded to the difference between the two self-risk estimates. Valence-dependent updating was assessed by comparing trials with good news (better-than-expected base rates with trials with bad news (worse-than-expected base rates. After receiving bad relative to good news, participants' updates were smaller and deviated more strongly from rational Bayesian predictions, indicating a valence-induced bias. Model comparison revealed that the biased (i.e., optimistic Bayesian model of belief updating better accounted for data than the unbiased (i.e., rational Bayesian model, confirming that the valence of the new information influenced the amount of updating. Moreover, alternative computational modeling based on reinforcement learning demonstrated higher learning rates for good than for bad news, as well as a moderating role of personal knowledge. Finally, in this specific experimental context, the approach based on

  7. 49 CFR 360.5 - Updating user fees.

    Science.gov (United States)

    2010-10-01

    ... updating the cost components comprising the fee. Cost components shall be updated as follows: (1) Direct... determined by the cost study in Regulations Governing Fees For Service, 1 I.C.C. 2d 60 (1984), or subsequent... by total office costs for the office directly associated with user fee activity. Actual updating of...

  8. La restricción intertemporal del presupuesto. Una evaluación empírica para el Gobierno Nacional Central de Colombia, 1950-2010

    Directory of Open Access Journals (Sweden)

    Hernando Chaves Álvaro

    2003-12-01

    Full Text Available En este documento se analiza la sostenibilidad fiscal del Gobierno Nacional Central en Colombia utilizando el enfoque de la Restricción Intertemporal de Presupuesto. Los resultados empíricos revelan que la estrategia fiscal actual es sostenible. No obstante, se vislumbran problemas de insolvencia en el largo plazo, lo que implica generar un mayor superávit primario en comparación con el actualmente programado. Lo anterior, se sustenta en los valores estimados de los indicadores de sostenibilidad fiscal.

  9. Second-generation speed limit map updating applications

    DEFF Research Database (Denmark)

    Tradisauskas, Nerius; Agerholm, Niels; Juhl, Jens

    2011-01-01

    Intelligent Speed Adaptation is an Intelligent Transport System developed to significantly improve road safety in helping car drivers maintain appropriate driving behaviour. The system works in connection with the speed limits on the road network. It is thus essential to keep the speed limit map...... used in the Intelligent Speed Adaptation scheme updated. The traditional method of updating speed limit maps on the basis of long time interval observations needed to be replaced by a more efficient speed limit updating tool. In a Danish Intelligent Speed Adaptation trial a web-based tool was therefore...... for map updating should preferably be made on the basis of a commercial map provider, 2 such as Google Maps and that the real challenge is to oblige road authorities to carry out updates....

  10. ADAS Update and Maintainability

    Science.gov (United States)

    Watson, Leela R.

    2010-01-01

    Since 2000, both the National Weather Service Melbourne (NWS MLB) and the Spaceflight Meteorology Group (SMG) have used a local data integration system (LOIS) as part of their forecast and warning operations. The original LOIS was developed by the Applied Meteorology Unit (AMU) in 1998 (Manobianco and Case 1998) and has undergone subsequent improvements. Each has benefited from three-dimensional (3-D) analyses that are delivered to forecasters every 15 minutes across the peninsula of Florida. The intent is to generate products that enhance short-range weather forecasts issued in support of NWS MLB and SMG operational requirements within East Central Florida. The current LDIS uses the Advanced Regional Prediction System (ARPS) Data Analysis System (AD AS) package as its core, which integrates a wide variety of national, regional, and local observational data sets. It assimilates all available real-time data within its domain and is run at a finer spatial and temporal resolution than current national or regional-scale analysis packages. As such, it provides local forecasters with a more comprehensive understanding of evolving fine-scale weather features. Over the years, the LDIS has become problematic to maintain since it depends on AMU-developed shell scripts that were written for an earlier version of the ADAS software. The goals of this task were to update the NWS MLB/SMG LDIS with the latest version of ADAS, incorporate new sources of observational data, and upgrade and modify the AMU-developed shell scripts written to govern the system. In addition, the previously developed ADAS graphical user interface (GUI) was updated. Operationally, these upgrades will result in more accurate depictions of the current local environment to help with short-range weather forecasting applications, while also offering an improved initialization for local versions of the Weather Research and Forecasting (WRF) model used by both groups.

  11. THE SYNTHETIC-OVERSAMPLING METHOD: USING PHOTOMETRIC COLORS TO DISCOVER EXTREMELY METAL-POOR STARS

    Energy Technology Data Exchange (ETDEWEB)

    Miller, A. A., E-mail: amiller@astro.caltech.edu [Jet Propulsion Laboratory, 4800 Oak Grove Drive, MS 169-506, Pasadena, CA 91109 (United States)

    2015-09-20

    Extremely metal-poor (EMP) stars ([Fe/H] ≤ −3.0 dex) provide a unique window into understanding the first generation of stars and early chemical enrichment of the universe. EMP stars are exceptionally rare, however, and the relatively small number of confirmed discoveries limits our ability to exploit these near-field probes of the first ∼500 Myr after the Big Bang. Here, a new method to photometrically estimate [Fe/H] from only broadband photometric colors is presented. I show that the method, which utilizes machine-learning algorithms and a training set of ∼170,000 stars with spectroscopically measured [Fe/H], produces a typical scatter of ∼0.29 dex. This performance is similar to what is achievable via low-resolution spectroscopy, and outperforms other photometric techniques, while also being more general. I further show that a slight alteration to the model, wherein synthetic EMP stars are added to the training set, yields the robust identification of EMP candidates. In particular, this synthetic-oversampling method recovers ∼20% of the EMP stars in the training set, at a precision of ∼0.05. Furthermore, ∼65% of the false positives from the model are very metal-poor stars ([Fe/H] ≤ −2.0 dex). The synthetic-oversampling method is biased toward the discovery of warm (∼F-type) stars, a consequence of the targeting bias from the Sloan Digital Sky Survey/Sloan Extension for Galactic Understanding survey. This EMP selection method represents a significant improvement over alternative broadband optical selection techniques. The models are applied to >12 million stars, with an expected yield of ∼600 new EMP stars, which promises to open new avenues for exploring the early universe.

  12. Vienaudžu vardarbība, pašvērtējums un empātija.

    OpenAIRE

    Krieva, Ilze

    2013-01-01

    Pētījuma mērķis bija noskaidrot vai pastāv saistība starp vienaudžu vardarbību, pašvērtējumu un empātijas līmeni. Pētījumā piedalījās desmitās un vienpadsmitās klases skolēni, pusaudži vecumā no 15-17 gadiem (n= 50). Pētījumā tika izmantotas šādas metodes: Vardarbības aptauja “Kā tev klājas skolā” (V.Rumpētere, balstoties uz T.Auroras izstrādāto aptauju par dzīvi skolā („The life in School checklist”, Aurora&Thompson, 1987), Pašvērtējuma aptauja (Rosenberg Self-Esteem Scale, Rosenberg,...

  13. State updating of a distributed hydrological model with Ensemble Kalman Filtering: Effects of updating frequency and observation network density on forecast accuracy

    Science.gov (United States)

    Rakovec, O.; Weerts, A.; Hazenberg, P.; Torfs, P.; Uijlenhoet, R.

    2012-12-01

    This paper presents a study on the optimal setup for discharge assimilation within a spatially distributed hydrological model (Rakovec et al., 2012a). The Ensemble Kalman filter (EnKF) is employed to update the grid-based distributed states of such an hourly spatially distributed version of the HBV-96 model. By using a physically based model for the routing, the time delay and attenuation are modelled more realistically. The discharge and states at a given time step are assumed to be dependent on the previous time step only (Markov property). Synthetic and real world experiments are carried out for the Upper Ourthe (1600 km2), a relatively quickly responding catchment in the Belgian Ardennes. The uncertain precipitation model forcings were obtained using a time-dependent multivariate spatial conditional simulation method (Rakovec et al., 2012b), which is further made conditional on preceding simulations. We assess the impact on the forecasted discharge of (1) various sets of the spatially distributed discharge gauges and (2) the filtering frequency. The results show that the hydrological forecast at the catchment outlet is improved by assimilating interior gauges. This augmentation of the observation vector improves the forecast more than increasing the updating frequency. In terms of the model states, the EnKF procedure is found to mainly change the pdfs of the two routing model storages, even when the uncertainty in the discharge simulations is smaller than the defined observation uncertainty. Rakovec, O., Weerts, A. H., Hazenberg, P., Torfs, P. J. J. F., and Uijlenhoet, R.: State updating of a distributed hydrological model with Ensemble Kalman Filtering: effects of updating frequency and observation network density on forecast accuracy, Hydrol. Earth Syst. Sci. Discuss., 9, 3961-3999, doi:10.5194/hessd-9-3961-2012, 2012a. Rakovec, O., Hazenberg, P., Torfs, P. J. J. F., Weerts, A. H., and Uijlenhoet, R.: Generating spatial precipitation ensembles: impact of

  14. El conductismo en la ciencia política: descifrando un concepto poco maleable en los horizontes de la investigación empírica

    OpenAIRE

    John Fredy Bedoya Marulanda

    2015-01-01

    Este artículo tiene como objetivo revivir el conductismo como una forma derealizar investigación empírica en la ciencia política, haciendo el llamado a lacientificidad de la disciplina con un objeto de estudio específico: elcomportamiento político de los individuos. Desde allí se presenta como sepuede definir el conductismo, sus cánones metodológicos y una aproximación acómo debe entenderse el comportamiento político.

  15. A economia da sonegação: teorias e evidências empíricas The economics of tax evasion: theories and emprirical evidences

    Directory of Open Access Journals (Sweden)

    Marcelo Lettieri Siqueira

    2005-12-01

    Full Text Available Este artigo fornece uma visão geral da literatura teórica e empírica, nacional e internacional, acerca do estudo econômico da sonegação de impostos. Após apresentar uma definição da sonegação fiscal, em confronto com a elisão fiscal, e analisar a questão da mensuração da sonegação, discutimos o modelo básico de análise da sonegação fiscal de Allingham e Sandmo (1972, apresentamos uma revisão de suas numerosas extensões, avaliamos os efeitos da política de imposição tributária sobre a decisão de sonegar e, por fim, examinamos as evidências empíricas acerca do comportamento do contribuinte e dos níveis de sonegação gerados por ele.This paper provides an overview of the findings of the theoretical and empirical literature on tax evasion. After we define tax evasion, as opposed to tax avoidance, and analyze the question of the tax evasion measurement, we discuss the Allingham and Sandmo's basic model on tax evasion, with a brief review of its numerous extensions, we deal with the effects of tax enforcement policy on the decision to evade taxes, and, finally, we survey the empirical evidence on taxpayer compliance and the tax gap produced for the taxpayer behavior.

  16. Breast Cancer and Estrogen-Alone Update

    Science.gov (United States)

    ... Current Issue Past Issues Research News From NIH Breast Cancer and Estrogen-Alone Update Past Issues / Summer 2006 ... hormone therapy does not increase the risk of breast cancer in postmenopausal women, according to an updated analysis ...

  17. Working Memory Updating as a Predictor of Academic Attainment

    Science.gov (United States)

    Lechuga, M. Teresa; Pelegrina, Santiago; Pelaez, Jose L.; Martin-Puga, M. Eva; Justicia, M. Jose

    2016-01-01

    There is growing evidence supporting the importance of executive functions, and specifically working memory updating (WMU), for children's academic achievement. This study aimed to assess the specific contribution of updating to the prediction of academic performance. Two updating tasks, which included different updating components, were…

  18. Role of update dynamics in the collective cooperation on the spatial snowdrift games: Beyond unconditional imitation and replicator dynamics

    International Nuclear Information System (INIS)

    Xia Chengyi; Wang Juan; Wang Li; Sun Shiwen; Sun Junqing; Wang Jinsong

    2012-01-01

    Highlights: ► We investigate the role of update rules in the spatial snowdrift game on regular lattices. ► Compared with UI and replicator rules, the cooperation can be further promoted by the Moran rule. ► f c and the cluster formation pattern for these three update rules are carefully explored. ► The frequency of cooperators is insensitive to the random initial set of players. - Abstract: In this paper, we investigate the role of update or imitation rules in the spatial snowdrift game on regular lattices. Three different update rules, including unconditional imitation (UI), replicator dynamics (RD) and the Moran process, are utilized to update the strategies of focal players during the game process in the spatial snowdrift on the lattice. We observe that the aggregate cooperation level between players is largely elevated by using the Moran process in the spatial snowdrift game, when compared to the UI or replicator dynamics. Meanwhile, we carefully explore the dynamical evolution of frequency of cooperators and the cluster formation pattern for these three update rules. Moreover, it is also shown that the evolutionary behavior under the Moran update is independent of and insensitive to the randomly initial configurations of cooperators and defectors. The current results clearly indicate that the introduction of moderate randomness in the strategy update will highly promote the maintenance and persistence of cooperation among selfish individuals, which will be greatly instrumental to deeply understand the evolution of cooperation within many natural, biological and social systems.

  19. La demanda de trabajo: teoría y evidencia empírica para el caso colombiano

    Directory of Open Access Journals (Sweden)

    Jairo Guillermo Isaza Castro

    2004-07-01

    Full Text Available Este documento presenta algunos de los aspectos teóricos más importantes para el análisis de la demanda de trabajo, así como la evidencia empírica disponible para el caso colombiano. En cuanto a los aspectos teóricos, la exposición se centra en la discusión microeonómica concerniente a las propiedades de la demanda de trabajo del empresario maximizador debeneficios que enfrenta un proceso productivo con dos factores: capital y trabajo. Luego se discuten las implicaciones de los procesos de liberalización y reformas estructurales en la demanda de trabajo. La revisión de literatura efectuada para el caso colombiano muestra cómo, en general, los estimativos de elasticidades de la demanda por trabajadores frente al producto y el salario real difieren sustancialmente debido a la diversidad de especificaciones econométricas, la temporalidad de los datos y las fuentes de los mismos.

  20. Using Cell Phone Technology for Self-Monitoring Procedures in Inclusive Settings

    Science.gov (United States)

    Bedesem, Pena L.

    2012-01-01

    The purpose of this study was to determine the effects and social validity of an innovative method of self-monitoring for middle school students with high-incidence disabilities in inclusive settings. An updated self-monitoring procedure, called CellF-Monitoring, utilized a cell phone as an all-inclusive self-monitoring device. The study took…

  1. Un análisis empírico de las no linealidades en la movilidad intergeneracional del ingreso. El caso de la Argentina

    OpenAIRE

    Jiménez, Maribel

    2017-01-01

    El principal objetivo de este estudio es cuantificar y examinar la movilidad intergeneracional del ingreso en la Argentina, explorando la hipótesis de variación del grado de (in)movilidad a lo largo de la distribución del ingreso correspondiente a los hijos así como a los padres, a través de la aplicación de métodos econométricos utilizados en la literatura empírica reciente para datos no longitudinales. Los resultados, obtenidos a partir de la información proveniente de dos muestras de la En...

  2. Un análisis empírico de las no linealidades en la movilidad intergeneracional del ingreso : El caso de la Argentina

    OpenAIRE

    Jiménez, Maribel

    2010-01-01

    El principal objetivo de este estudio es cuantificar y examinar la movilidad intergeneracional del ingreso en la Argentina, explorando la hipótesis de variación del grado de (in)movilidad a lo largo de la distribución del ingreso correspondiente a los hijos así como a los padres, a través de la aplicación de métodos econométricos utilizados en la literatura empírica reciente para datos no longitudinales. Los resultados, obtenidos a partir de la información proveniente de dos muestras de la En...

  3. Expanded and updated data and a query pipeline for iBeetle-Base.

    Science.gov (United States)

    Dönitz, Jürgen; Gerischer, Lizzy; Hahnke, Stefan; Pfeiffer, Stefan; Bucher, Gregor

    2018-01-04

    The iBeetle-Base provides access to sequence and phenotype information for genes of the beetle Tribolium castaneum. It has been updated including more and updated data and new functions. RNAi phenotypes are now available for >50% of the genes, which represents an expansion of 60% compared to the previous version. Gene sequence information has been updated based on the new official gene set OGS3 and covers all genes. Interoperability with FlyBase has been enhanced: First, gene information pages of homologous genes are interlinked between both databases. Second, some steps of a new query pipeline allow transforming gene lists from either species into lists with related gene IDs, names or GO terms. This facilitates the comparative analysis of gene functions between fly and beetle. The backend of the pipeline is implemented as endpoints of a RESTful interface, such that it can be reused by other projects or tools. A novel online interface allows the community to propose GO terms for their gene of interest expanding the range of animals where GO terms are defined. iBeetle-Base is available at http://ibeetle-base.uni-goettingen.de/. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  4. Combining A Priori Knowledge and Sensor Information for Updating the Global Position of an Autonomous Vehicle

    NARCIS (Netherlands)

    Zivkovic, Z.; Schoute, Albert L.; van der Heijden, Ferdinand; van Amerongen, J.; Jonker, B.; Regtien, P.P.L; Stramigioli, S.

    The problem of updating the global position of an autonomous vehicle is considered. An iterative procedure is proposed to fit a map to a set of noisy measurements. The procedure is inspired by a non-parametric procedure for probability density function mode searching. We show how this could be used

  5. Enhanced 3D PET OSEM reconstruction using inter-update Metz filtering

    International Nuclear Information System (INIS)

    Jacobson, M.; Levkovitz, R.; Ben-Tal, A.; Thielemans, K.; Spinks, T.; Belluzzo, D.; Pagani, E.; Bettinardi, V.; Gilardi, M.C.; Zverovich, A.; Mitra, G.

    2000-01-01

    We present an enhancement of the OSEM (ordered set expectation maximization) algorithm for 3D PET reconstruction, which we call the inter-update Metz filtered OSEM (IMF-OSEM). The IMF-OSEM algorithm incorporates filtering action into the image updating process in order to improve the quality of the reconstruction. With this technique, the multiplicative correction image - ordinarily used to update image estimates in plain OSEM - is applied to a Metz-filtered version of the image estimate at certain intervals. In addition, we present a software implementation that employs several high-speed features to accelerate reconstruction. These features include, firstly, forward and back projection functions which make full use of symmetry as well as a fast incremental computation technique. Secondly, the software has the capability of running in parallel mode on several processors. The parallelization approach employed yields a significant speed-up, which is nearly independent of the amount of data. Together, these features lead to reasonable reconstruction times even when using large image arrays and non-axially compressed projection data. The performance of IMF-OSEM was tested on phantom data acquired on the GE Advance scanner. Our results demonstrate that an appropriate choice of Metz filter parameters can improve the contrast-noise balance of certain regions of interest relative to both plain and post-filtered OSEM, and to the GE commercial reprojection algorithm software. (author)

  6. Apollo guidance, navigation and control: Guidance system operations plans for manned LM earth orbital and lunar missions using Program COLOSSUS 3. Section 7: Erasable memory programs

    Science.gov (United States)

    Hamilton, M. H.

    1972-01-01

    Erasable-memory programs (EMPs) designed for the guidance computers used in the command (CMC) and lunar modules (LGC) are described. CMC programs are designated COLOSSUS 3, and the associated EMPs are identified by a three-digit number beginning with 5. LGC programs are designated LUMINARY 1E, and the associated EMPs are identified, with one exception, by a three-digit number beginning with 1. The exception is EMP 99. The EMPs vary in complexity from a simple flagbit setting to a long and intricate logical structure. They all, however, cause the computer to behave in a way not intended in the original design of the programs; they accomplish this off-nominal behavior by some alteration of erasable memory to interface with existing fixed-memory programs to effect a desired result.

  7. Resiliencia en Enfermería: definición, evidencia empírica e intervenciones

    Directory of Open Access Journals (Sweden)

    Óscar Arrogante

    2015-12-01

    Full Text Available La resiliencia (adaptación positiva a la adversidad se encuentra dentro de las competencias enfermeras al relacionarse con tres diagnósticos de la taxonomía NANDA y, además, la investigación enfermera señala que es una característica propia de la Enfermería. Sin embargo, la resiliencia es un concepto novedoso para la mayoría de las enfermeras. El artículo tiene como objetivos definir el concepto de resiliencia, exponer la evidencia empírica encontrada en la investigación enfermera y describir los principales programas e intervenciones para su desarrollo. La resiliencia tiene importantes implicaciones clínicas tanto para el cuidado de pacientes, como para el propio autocuidado de la Enfermería. La resiliencia se puede considerar como una característica esencial e inherente a la Enfermería debido a la exposición continua al sufrimiento humano y a unas condiciones laborales estresantes. Por lo tanto, su entrenamiento debería promoverse desde las universidades hasta los centros sanitarios para mejorar la práctica clínica enfermera.

  8. Final report for EMP instrumentation project DNA IACRO 75-815: magnetic thin film sensors

    International Nuclear Information System (INIS)

    Hsieh, E.J.; Miller, D.E.; Vindelov, K.E.; Brown, T.G.

    1975-01-01

    The magnetic thin film current sensor/recorder is a passive device which responds to the peak current and pulse shape of a transient event. The transient current information becomes a permanent record on the film. The thin film device is small, low mass and reusable. It has been proven to be fast (less than 1/2 nanosecond response), radiation hard and applicable to peak current measurement of both CW and pulsed signals. The sensors were initially developed at LLL for pulse-energy measurement on exploding wires. Later the Defense Nuclear Agency sponsored the present project to develop the magnetic thin film devices as EMP diagnostic tools. The Air Force Weapons Lab supported the work to test the field capabilities of the thin film devices at ARES test facility, Kirtland AFB. Sandia Lab is now using a new version of the thin film sensors to monitor the transient current induced by intense radiation in their hybrid microcircuits. Also, a field test has been planned with Naval Electronics Laboratory Center where the thin film sensors are to be used to measure peak CW current caused by rf radiation. Research results are summarized

  9. A experiência brasileira com o core set da classificação internacional de funcionalidade, incapacidade e saúde para lombalgia La experiencia brasileña con el core set de la clasificación internacional de funcionalidad, incapacidad y salud para dorsalgia The Brazilian experience with the international classification of functioning, disability and health core set for low back pain

    Directory of Open Access Journals (Sweden)

    Marcelo Riberto

    2011-01-01

    Full Text Available OBJETIVO: Validar empiricamente o core set da CIF para lombalgia e descrever a funcionalidade de uma amostra de pacientes com lombalgia mecânica crônica inespecífica. MÉTODOS: Vinte e nove pacientes de um centro de reabilitação foram avaliados por meio do core set da CIF para lombalgia e pelo questionário de Roland Morris (QRM e SF-36. RESULTADOS: Todas as categorias de estruturas do corpo do core set se mostraram comprometidas em ao menos 80% dos pacientes, sendo consideradas validadas. Entre as 19 categorias de Funções do corpo, apenas quatro estavam comprometidas em menos que 80% dos pacientes, sendo consideradas não-validadas, o mesmo foi observado para cinco das 29 de Atividades e participações e cinco das 25 categorias de Fatores ambientais. CONCLUSÕES: As categorias selecionadas para o core set da CIF para lombalgia foram consideradas empiricamente validadas e em conjunto permitiram descrever a multiplicidade de repercussões dessa condição de saúde sobre a funcionalidade das pessoas. O core set da CIF serve para guiar a intervenção terapêutica interdisciplinar.OBJETIVO: Validar empíricamente el core set de la CIF para dorsalgia y describir la funcionalidad de una muestra de pacientes con dorsalgia mecánica crónica inespecífica. MÉTODOS: Veintinueve pacientes de un centro de rehabilitación fueron evaluados por medio del core set de la CIF para dorsalgia, y mediante el cuestionario Roland Moris (QRM y SF-36. RESULTADOS: Todas las categorías de Estructuras del cuerpo del core set se mostraron comprometidas en por lo menos 80% de los pacientes, siendo consideradas validadas. Entre las 19 categorías de Funciones del cuerpo, sólo cuatro estaban comprometidas en menos de 80% de los pacientes, siendo consideradas como no validadas; lo mismo fue observado para 5 de las 29 categorías de Actividades y participaciones, y 5 de las 25 categorías de Factores ambientales. CONCLUSIONES: Las categorías seleccionadas para el

  10. Hospitalidade Organizacional: Panorama Teórico-Empírico

    Directory of Open Access Journals (Sweden)

    José Alberto Carvalho dos Santos Claro

    2015-10-01

    Full Text Available O objetivo deste texto é o de apresentar as discussões teórico-conceituais sobre Hospitalidade, particularmente a vertente da Hospitalidade Organizacional (HO, que se ocupa das relações hospitaleiras no ambiente do espaço de trabalho. Trata-se de um estudo exploratório, baseado em revisão bibliográfica, seguida de pesquisa de campo por meio de levantamento junto a gestores de pessoas (especialistas ou juízes, sobre o entendimento do tema, visando contribuir para a futura criação de escala de medida para quantificar o grau de HO em uma organização. Como resultado, apresenta-se contribuição teórica para o amadurecimento desta tendência organizacional e indicadores que poderão ser futuramente usados em estudos empíricos e na construção de um instrumento com escala validada para ser utilizada em organizações em qualquer setor de atividade econômica. Palavras-chave: Hospitalidade. Hospitalidade Organizacional. Gestão de Pessoas.Organizational Hospitality: Theorical and Empirical Developments This paper aim is to present the theoretical and conceptual discussions about hospitality, particularly the  Organizational Hospitality (OH, which is concerned with the hospitable relations in the workplace. It’s an exploratory study, based on literature review and field survey with people managers (experts or judges about their understanding about the question. The result indicates that the development of organizational indicators could be used in future empirical studies and to the construction of a validated scale that can be used in any sector of the economic activity. Keywords: Hospitality. Organizational Hospitality. People Management. Indicators.José Alberto Carvalho dos Santos Claro – Doutor. Professor Adjunto da Universidade Federal de São Paulo [UNIFESP], Campus Baixada Santista, Santos, SP. Endereço Lattes http://lattes.cnpq.br/0865792662046289 E-mail: albertoclaro@albertoclaro.pro.br  

  11. MO-AB-207-04: ACR Update in Mammography

    International Nuclear Information System (INIS)

    Berns, E.

    2015-01-01

    A goal of an imaging accreditation program is to ensure adequate image quality, verify appropriate staff qualifications, and to assure patient and personnel safety. Currently, more than 35,000 facilities in 10 modalities have been accredited by the American College of Radiology (ACR), making the ACR program one of the most prolific accreditation options in the U.S. In addition, ACR is one of the accepted accreditations required by some state laws, CMS/MIPPA insurance and others. Familiarity with the ACR accreditation process is therefore essential to clinical diagnostic medical physicists. Maintaining sufficient knowledge of the ACR program must include keeping up-to-date as the various modality requirements are refined to better serve the goals of the program and to accommodate newer technologies and practices. This session consists of presentations from authorities in four ACR accreditation modality programs, including magnetic resonance imaging, computed tomography, nuclear medicine, and mammography. Each speaker will discuss the general components of the modality program and address any recent changes to the requirements. Learning Objectives: To understand the requirements of the ACR MR Accreditation program. The discussion will include accreditation of whole-body general purpose magnets, dedicated extremity systems well as breast MRI accreditation. Anticipated updates to the ACR MRI Quality Control Manual will also be reviewed. To understand the requirements of the ACR CT accreditation program, including updates to the QC manual as well as updates through the FAQ process. To understand the requirements of the ACR nuclear medicine accreditation program, and the role of the physicist in annual equipment surveys and the set up and supervision of the routine QC program. To understand the current ACR MAP Accreditation requirement and present the concepts and structure of the forthcoming ACR Digital Mammography QC Manual and Program

  12. MO-AB-207-02: ACR Update in MR

    International Nuclear Information System (INIS)

    Price, R.

    2015-01-01

    A goal of an imaging accreditation program is to ensure adequate image quality, verify appropriate staff qualifications, and to assure patient and personnel safety. Currently, more than 35,000 facilities in 10 modalities have been accredited by the American College of Radiology (ACR), making the ACR program one of the most prolific accreditation options in the U.S. In addition, ACR is one of the accepted accreditations required by some state laws, CMS/MIPPA insurance and others. Familiarity with the ACR accreditation process is therefore essential to clinical diagnostic medical physicists. Maintaining sufficient knowledge of the ACR program must include keeping up-to-date as the various modality requirements are refined to better serve the goals of the program and to accommodate newer technologies and practices. This session consists of presentations from authorities in four ACR accreditation modality programs, including magnetic resonance imaging, computed tomography, nuclear medicine, and mammography. Each speaker will discuss the general components of the modality program and address any recent changes to the requirements. Learning Objectives: To understand the requirements of the ACR MR Accreditation program. The discussion will include accreditation of whole-body general purpose magnets, dedicated extremity systems well as breast MRI accreditation. Anticipated updates to the ACR MRI Quality Control Manual will also be reviewed. To understand the requirements of the ACR CT accreditation program, including updates to the QC manual as well as updates through the FAQ process. To understand the requirements of the ACR nuclear medicine accreditation program, and the role of the physicist in annual equipment surveys and the set up and supervision of the routine QC program. To understand the current ACR MAP Accreditation requirement and present the concepts and structure of the forthcoming ACR Digital Mammography QC Manual and Program

  13. MO-AB-207-04: ACR Update in Mammography

    Energy Technology Data Exchange (ETDEWEB)

    Berns, E. [University of Colorado Health Science (United States)

    2015-06-15

    A goal of an imaging accreditation program is to ensure adequate image quality, verify appropriate staff qualifications, and to assure patient and personnel safety. Currently, more than 35,000 facilities in 10 modalities have been accredited by the American College of Radiology (ACR), making the ACR program one of the most prolific accreditation options in the U.S. In addition, ACR is one of the accepted accreditations required by some state laws, CMS/MIPPA insurance and others. Familiarity with the ACR accreditation process is therefore essential to clinical diagnostic medical physicists. Maintaining sufficient knowledge of the ACR program must include keeping up-to-date as the various modality requirements are refined to better serve the goals of the program and to accommodate newer technologies and practices. This session consists of presentations from authorities in four ACR accreditation modality programs, including magnetic resonance imaging, computed tomography, nuclear medicine, and mammography. Each speaker will discuss the general components of the modality program and address any recent changes to the requirements. Learning Objectives: To understand the requirements of the ACR MR Accreditation program. The discussion will include accreditation of whole-body general purpose magnets, dedicated extremity systems well as breast MRI accreditation. Anticipated updates to the ACR MRI Quality Control Manual will also be reviewed. To understand the requirements of the ACR CT accreditation program, including updates to the QC manual as well as updates through the FAQ process. To understand the requirements of the ACR nuclear medicine accreditation program, and the role of the physicist in annual equipment surveys and the set up and supervision of the routine QC program. To understand the current ACR MAP Accreditation requirement and present the concepts and structure of the forthcoming ACR Digital Mammography QC Manual and Program.

  14. MO-AB-207-02: ACR Update in MR

    Energy Technology Data Exchange (ETDEWEB)

    Price, R. [Vanderbilt Medical Center (United States)

    2015-06-15

    A goal of an imaging accreditation program is to ensure adequate image quality, verify appropriate staff qualifications, and to assure patient and personnel safety. Currently, more than 35,000 facilities in 10 modalities have been accredited by the American College of Radiology (ACR), making the ACR program one of the most prolific accreditation options in the U.S. In addition, ACR is one of the accepted accreditations required by some state laws, CMS/MIPPA insurance and others. Familiarity with the ACR accreditation process is therefore essential to clinical diagnostic medical physicists. Maintaining sufficient knowledge of the ACR program must include keeping up-to-date as the various modality requirements are refined to better serve the goals of the program and to accommodate newer technologies and practices. This session consists of presentations from authorities in four ACR accreditation modality programs, including magnetic resonance imaging, computed tomography, nuclear medicine, and mammography. Each speaker will discuss the general components of the modality program and address any recent changes to the requirements. Learning Objectives: To understand the requirements of the ACR MR Accreditation program. The discussion will include accreditation of whole-body general purpose magnets, dedicated extremity systems well as breast MRI accreditation. Anticipated updates to the ACR MRI Quality Control Manual will also be reviewed. To understand the requirements of the ACR CT accreditation program, including updates to the QC manual as well as updates through the FAQ process. To understand the requirements of the ACR nuclear medicine accreditation program, and the role of the physicist in annual equipment surveys and the set up and supervision of the routine QC program. To understand the current ACR MAP Accreditation requirement and present the concepts and structure of the forthcoming ACR Digital Mammography QC Manual and Program.

  15. MO-AB-207-01: ACR Update in CT

    Energy Technology Data Exchange (ETDEWEB)

    McNitt-Gray, M. [UCLA School of Medicine (United States)

    2015-06-15

    A goal of an imaging accreditation program is to ensure adequate image quality, verify appropriate staff qualifications, and to assure patient and personnel safety. Currently, more than 35,000 facilities in 10 modalities have been accredited by the American College of Radiology (ACR), making the ACR program one of the most prolific accreditation options in the U.S. In addition, ACR is one of the accepted accreditations required by some state laws, CMS/MIPPA insurance and others. Familiarity with the ACR accreditation process is therefore essential to clinical diagnostic medical physicists. Maintaining sufficient knowledge of the ACR program must include keeping up-to-date as the various modality requirements are refined to better serve the goals of the program and to accommodate newer technologies and practices. This session consists of presentations from authorities in four ACR accreditation modality programs, including magnetic resonance imaging, computed tomography, nuclear medicine, and mammography. Each speaker will discuss the general components of the modality program and address any recent changes to the requirements. Learning Objectives: To understand the requirements of the ACR MR Accreditation program. The discussion will include accreditation of whole-body general purpose magnets, dedicated extremity systems well as breast MRI accreditation. Anticipated updates to the ACR MRI Quality Control Manual will also be reviewed. To understand the requirements of the ACR CT accreditation program, including updates to the QC manual as well as updates through the FAQ process. To understand the requirements of the ACR nuclear medicine accreditation program, and the role of the physicist in annual equipment surveys and the set up and supervision of the routine QC program. To understand the current ACR MAP Accreditation requirement and present the concepts and structure of the forthcoming ACR Digital Mammography QC Manual and Program.

  16. A systematic decision-making process on the need for updating clinical practice guidelines proved to be feasible in a pilot study.

    Science.gov (United States)

    Becker, Monika; Jaschinski, Thomas; Eikermann, Michaela; Mathes, Tim; Bühn, Stefanie; Koppert, Wolfgang; Leffler, Andreas; Neugebauer, Edmund; Pieper, Dawid

    2018-04-01

    The objective of this study was to test and evaluate a new decision-making process on the need for updating within the update of a German clinical practice guideline (CPG). The pilot study comprised (1) limited searches in Pubmed to identify new potentially relevant evidence, (2) an online survey among the members of the CPG group to assess the need for update, and (3) a consensus conference for determination and prioritization of guideline sections with a high need for update. Subsequently, we conducted a second online survey to evaluate the procedure. The searches resulted in 902 abstracts that were graded as new potentially relevant evidence. Twenty five of 39 members of the CPG group (64%) participated in the online survey. Seventy six percent of those took part in the second online survey. The evaluation study found on average a grade of support of the procedure regarding the determination of the need for update of 3.65 (standard deviation: 0.76) on a likert scale with 1 = "no support" to 5 = "very strong support." The conducted procedure presents a systematic approach for assessing whether and to what extent a CPG requires updating and enables setting priorities for which particular guideline section to update within a CPG. Copyright © 2018 Elsevier Inc. All rights reserved.

  17. Updating parameters of the chicken processing line model

    DEFF Research Database (Denmark)

    Kurowicka, Dorota; Nauta, Maarten; Jozwiak, Katarzyna

    2010-01-01

    A mathematical model of chicken processing that quantitatively describes the transmission of Campylobacter on chicken carcasses from slaughter to chicken meat product has been developed in Nauta et al. (2005). This model was quantified with expert judgment. Recent availability of data allows...... updating parameters of the model to better describe processes observed in slaughterhouses. We propose Bayesian updating as a suitable technique to update expert judgment with microbiological data. Berrang and Dickens’s data are used to demonstrate performance of this method in updating parameters...... of the chicken processing line model....

  18. Better Plants Progress Update Fall 2013

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2013-09-23

    This Progress Update summarizes the significant energy saving achievements and cumulative cost savings made by these industry leaders from 2010-2012. The update also shares the plans and priorities over the next year for the Better Plants Program to continue to advance energy efficiency in the industrial sector.

  19. Non-Linear Approximation of Bayesian Update

    KAUST Repository

    Litvinenko, Alexander

    2016-01-01

    We develop a non-linear approximation of expensive Bayesian formula. This non-linear approximation is applied directly to Polynomial Chaos Coefficients. In this way, we avoid Monte Carlo sampling and sampling error. We can show that the famous Kalman Update formula is a particular case of this update.

  20. Non-Linear Approximation of Bayesian Update

    KAUST Repository

    Litvinenko, Alexander

    2016-06-23

    We develop a non-linear approximation of expensive Bayesian formula. This non-linear approximation is applied directly to Polynomial Chaos Coefficients. In this way, we avoid Monte Carlo sampling and sampling error. We can show that the famous Kalman Update formula is a particular case of this update.

  1. Indoor Spatial Updating with Reduced Visual Information

    OpenAIRE

    Legge, Gordon E.; Gage, Rachel; Baek, Yihwa; Bochsler, Tiana M.

    2016-01-01

    Purpose Spatial updating refers to the ability to keep track of position and orientation while moving through an environment. People with impaired vision may be less accurate in spatial updating with adverse consequences for indoor navigation. In this study, we asked how artificial restrictions on visual acuity and field size affect spatial updating, and also judgments of the size of rooms. Methods Normally sighted young adults were tested with artificial restriction of acuity in Mild Blur (S...

  2. Model parameter updating using Bayesian networks

    International Nuclear Information System (INIS)

    Treml, C.A.; Ross, Timothy J.

    2004-01-01

    This paper outlines a model parameter updating technique for a new method of model validation using a modified model reference adaptive control (MRAC) framework with Bayesian Networks (BNs). The model parameter updating within this method is generic in the sense that the model/simulation to be validated is treated as a black box. It must have updateable parameters to which its outputs are sensitive, and those outputs must have metrics that can be compared to that of the model reference, i.e., experimental data. Furthermore, no assumptions are made about the statistics of the model parameter uncertainty, only upper and lower bounds need to be specified. This method is designed for situations where a model is not intended to predict a complete point-by-point time domain description of the item/system behavior; rather, there are specific points, features, or events of interest that need to be predicted. These specific points are compared to the model reference derived from actual experimental data. The logic for updating the model parameters to match the model reference is formed via a BN. The nodes of this BN consist of updateable model input parameters and the specific output values or features of interest. Each time the model is executed, the input/output pairs are used to adapt the conditional probabilities of the BN. Each iteration further refines the inferred model parameters to produce the desired model output. After parameter updating is complete and model inputs are inferred, reliabilities for the model output are supplied. Finally, this method is applied to a simulation of a resonance control cooling system for a prototype coupled cavity linac. The results are compared to experimental data.

  3. NLSdb-major update for database of nuclear localization signals and nuclear export signals.

    Science.gov (United States)

    Bernhofer, Michael; Goldberg, Tatyana; Wolf, Silvana; Ahmed, Mohamed; Zaugg, Julian; Boden, Mikael; Rost, Burkhard

    2018-01-04

    NLSdb is a database collecting nuclear export signals (NES) and nuclear localization signals (NLS) along with experimentally annotated nuclear and non-nuclear proteins. NES and NLS are short sequence motifs related to protein transport out of and into the nucleus. The updated NLSdb now contains 2253 NLS and introduces 398 NES. The potential sets of novel NES and NLS have been generated by a simple 'in silico mutagenesis' protocol. We started with motifs annotated by experiments. In step 1, we increased specificity such that no known non-nuclear protein matched the refined motif. In step 2, we increased the sensitivity trying to match several different families with a motif. We then iterated over steps 1 and 2. The final set of 2253 NLS motifs matched 35% of 8421 experimentally verified nuclear proteins (up from 21% for the previous version) and none of 18 278 non-nuclear proteins. We updated the web interface providing multiple options to search protein sequences for NES and NLS motifs, and to evaluate your own signal sequences. NLSdb can be accessed via Rostlab services at: https://rostlab.org/services/nlsdb/. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  4. Nonsynchronous updating in the multiverse of cellular automata.

    Science.gov (United States)

    Reia, Sandro M; Kinouchi, Osame

    2015-04-01

    In this paper we study updating effects on cellular automata rule space. We consider a subset of 6144 order-3 automata from the space of 262144 bidimensional outer-totalistic rules. We compare synchronous to asynchronous and sequential updatings. Focusing on two automata, we discuss how update changes destroy typical structures of these rules. Besides, we show that the first-order phase transition in the multiverse of synchronous cellular automata, revealed with the use of a recently introduced control parameter, seems to be robust not only to changes in update schema but also to different initial densities.

  5. Nonsynchronous updating in the multiverse of cellular automata

    Science.gov (United States)

    Reia, Sandro M.; Kinouchi, Osame

    2015-04-01

    In this paper we study updating effects on cellular automata rule space. We consider a subset of 6144 order-3 automata from the space of 262144 bidimensional outer-totalistic rules. We compare synchronous to asynchronous and sequential updatings. Focusing on two automata, we discuss how update changes destroy typical structures of these rules. Besides, we show that the first-order phase transition in the multiverse of synchronous cellular automata, revealed with the use of a recently introduced control parameter, seems to be robust not only to changes in update schema but also to different initial densities.

  6. New uses of sulfur - update

    Energy Technology Data Exchange (ETDEWEB)

    Almond, K.P.

    1995-07-01

    An update to an extensive bibliography on alternate uses of sulfur was presented. Alberta Sulphur Research Ltd., previously compiled a bibliography in volume 24 of this quarterly bulletin. This update provides an additional 44 new publications. The information regarding current research focusses on topics regarding the use of sulfur in oil and gas applications, mining and metallurgy, concretes and other structural materials, waste management, rubber and textile products, asphalts and other paving and highway applications.

  7. News and Features Updates from USA.gov

    Data.gov (United States)

    General Services Administration — Stay on top of important government news and information with the USA.gov Updates: News and Features RSS feed. We'll update this feed when we add news and featured...

  8. Physician Bayesian updating from personal beliefs about the base rate and likelihood ratio.

    Science.gov (United States)

    Rottman, Benjamin Margolin

    2017-02-01

    Whether humans can accurately make decisions in line with Bayes' rule has been one of the most important yet contentious topics in cognitive psychology. Though a number of paradigms have been used for studying Bayesian updating, rarely have subjects been allowed to use their own preexisting beliefs about the prior and the likelihood. A study is reported in which physicians judged the posttest probability of a diagnosis for a patient vignette after receiving a test result, and the physicians' posttest judgments were compared to the normative posttest calculated from their own beliefs in the sensitivity and false positive rate of the test (likelihood ratio) and prior probability of the diagnosis. On the one hand, the posttest judgments were strongly related to the physicians' beliefs about both the prior probability as well as the likelihood ratio, and the priors were used considerably more strongly than in previous research. On the other hand, both the prior and the likelihoods were still not used quite as much as they should have been, and there was evidence of other nonnormative aspects to the updating, such as updating independent of the likelihood beliefs. By focusing on how physicians use their own prior beliefs for Bayesian updating, this study provides insight into how well experts perform probabilistic inference in settings in which they rely upon their own prior beliefs rather than experimenter-provided cues. It suggests that there is reason to be optimistic about experts' abilities, but that there is still considerable need for improvement.

  9. State updating of a distributed hydrological model with Ensemble Kalman Filtering: effects of updating frequency and observation network density on forecast accuracy

    Directory of Open Access Journals (Sweden)

    O. Rakovec

    2012-09-01

    Full Text Available This paper presents a study on the optimal setup for discharge assimilation within a spatially distributed hydrological model. The Ensemble Kalman filter (EnKF is employed to update the grid-based distributed states of such an hourly spatially distributed version of the HBV-96 model. By using a physically based model for the routing, the time delay and attenuation are modelled more realistically. The discharge and states at a given time step are assumed to be dependent on the previous time step only (Markov property.

    Synthetic and real world experiments are carried out for the Upper Ourthe (1600 km2, a relatively quickly responding catchment in the Belgian Ardennes. We assess the impact on the forecasted discharge of (1 various sets of the spatially distributed discharge gauges and (2 the filtering frequency. The results show that the hydrological forecast at the catchment outlet is improved by assimilating interior gauges. This augmentation of the observation vector improves the forecast more than increasing the updating frequency. In terms of the model states, the EnKF procedure is found to mainly change the pdfs of the two routing model storages, even when the uncertainty in the discharge simulations is smaller than the defined observation uncertainty.

  10. Rebuild America partner update, November--December 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-11-01

    This issue of the update includes articles on retrofitting Duke University facilities, energy efficiency updates to buildings in Portland, Oregon, Salisbury, North Carolina, Hawaii, Roanoke-Chowan, Virginia, and energy savings centered designs for lighting systems.

  11. Co-operation and Phase Behavior under the Mixed Updating Rules

    International Nuclear Information System (INIS)

    Zhang Wen; Li Yao-Sheng; Xu Chen

    2015-01-01

    We present a model by considering two updating rules when the agents play prisoner's dilemma on a square lattice. Agents can update their strategies by referencing one of his neighbors of higher payoffs under the imitation updating rule or directly replaced by one of his neighbors according to the death-birth updating rule. The frequency of co-operation is related to the probability q of occurrence of the imitation updating or the death-birth updating and the game parameter b. The death-birth updating rule favors the co-operation while the imitation updating rule favors the defection on the lattice, although both rules suppress the co-operation in the well-mixed population. Therefore a totally co-operative state may emerge when the death-birth updating is involved in the evolution when b is relatively small. We also obtain a phase diagram on the q-b plane. There are three phases on the plane with two pure phases of a totally co-operative state and a totally defective state and a mixing phase of mixed strategies. Based on the pair approximation, we theoretically analyze the phase behavior and obtain a quantitative agreement with the simulation results. (paper)

  12. Federal Education Update, December 2004. Commission Update 04-17.

    Science.gov (United States)

    California Postsecondary Education Commission, 2004

    2004-01-01

    This update presents some of the major issues affecting education occurring at the national level. These include: Higher Education Act Extended for One Year; New Law Increases Loan Forgiveness for Teachers; Domestic Appropriations Measures Completed; Change in Federal Student Aid Rules; Bush Advisor Nominated To Be Education Secretary In Second…

  13. Agent Communication for Dynamic Belief Update

    Science.gov (United States)

    Kobayashi, Mikito; Tojo, Satoshi

    Thus far, various formalizations of rational / logical agent model have been proposed. In this paper, we include the notion of communication channel and belief modality into update logic, and introduce Belief Update Logic (BUL). First, we discuss that how we can reformalize the inform action of FIPA-ACL into communication channel, which represents a connection between agents. Thus, our agents can send a message only when they believe, and also there actually is, a channel between him / her and a receiver. Then, we present a static belief logic (BL) and show its soundness and completeness. Next, we develop the logic to BUL, which can update Kripke model by the inform action; in which we show that in the updated model the belief operator also satisfies K45. Thereafter, we show that every sentence in BUL can be translated into BL; thus, we can contend that BUL is also sound and complete. Furthermore, we discuss the features of CUL, including the case of inconsistent information, as well as channel transmission. Finally, we summarize our contribution and discuss some future issues.

  14. Global baby-friendly hospital initiative monitoring data: update and discussion.

    Science.gov (United States)

    Labbok, Miriam H

    2012-08-01

    The World Health Organization (WHO)/UNICEF Baby-Friendly Hospital Initiative (BFHI) was developed to support the implementation of the Ten Steps for Successful Breastfeeding. The purpose of this study is to assess trends in the numbers facilities ever-designated "baby-friendly," to consider uptake of the new WHO/UNICEF BFHI materials, and to consider implications for future breastfeeding support. The national contacts from the 2006-2007 UNICEF BFHI update were recontacted, as were WHO and UNICEF officers worldwide, to ascertain the number of hospitals ever-designated "baby-friendly," presence of a government breastfeeding oversight committee, use of the new BFHI materials and, if yes, use of the new maternity or human immunodeficiency virus (HIV) materials. Seventy countries reporting in 2010-2011 and the updates from an additional 61 reporting in 2006-2007 (n=131, or 66% of the 198 countries) confirm that there are at least 21,328 ever-designated facilities. This is 27.5% of maternities worldwide: 8.5% of those in industrialized countries and 31% in less developed settings. In 2010, government committees were reported by 18 countries, and 34 reported using the new BFHI materials: 14 reported using the maternity care and 11 reported using the HIV materials. Rates of increase in the number of ever-certified "baby-friendly" hospitals vary by region and show some chronological correlation with trends in breastfeeding rates. Although it is not possible to attribute this increase to the BFHI alone, there is ongoing interest in Ten Steps implementation and in BFHI. The continued growth may reflect the dedication of ministries of health and national BFHI groups, as well as increasing recognition that the Ten Steps are effective quality improvement practices that increase breastfeeding and synergize with community interventions and other program efforts. With renewed interest in maternal/neonatal health, revitalization of support for Ten Steps and their effective

  15. Communication technology update and fundamentals

    CERN Document Server

    Grant, August E

    2010-01-01

    New communication technologies are being introduced at an astonishing rate. Making sense of these technologies is increasingly difficult. Communication Technology Update and Fundamentals is the single best source for the latest developments, trends, and issues in communication technology. Featuring the fundamental framework along with the history and background of communication technologies, Communication Technology Update and Fundamentals, 12th edition helps you stay ahead of these ever-changing and emerging technologies.As always, every chapter ha

  16. Communication technology update and fundamentals

    CERN Document Server

    Grant, August E

    2008-01-01

    New communication technologies are being introduced at an astonishing rate. Making sense of these technologies is increasingly difficult. Communication Technology Update is the single best source for the latest developments, trends, and issues in communication technology. Now in its 11th edition, Communication Technology Update has become an indispensable information resource for business, government, and academia. As always, every chapter has been completely rewritten to reflect the latest developments and market statistics, and now covers mobile computing, dig

  17. Updated safety analysis of ITER

    Energy Technology Data Exchange (ETDEWEB)

    Taylor, Neill, E-mail: neill.taylor@iter.org [ITER Organization, CS 90 046, 13067 St Paul Lez Durance Cedex (France); Baker, Dennis; Ciattaglia, Sergio; Cortes, Pierre; Elbez-Uzan, Joelle; Iseli, Markus; Reyes, Susana; Rodriguez-Rodrigo, Lina; Rosanvallon, Sandrine; Topilski, Leonid [ITER Organization, CS 90 046, 13067 St Paul Lez Durance Cedex (France)

    2011-10-15

    An updated version of the ITER Preliminary Safety Report has been produced and submitted to the licensing authorities. It is revised and expanded in response to requests from the authorities after their review of an earlier version in 2008, to reflect enhancements in ITER safety provisions through design changes, to incorporate new and improved safety analyses and to take into account other ITER design evolution. The updated analyses show that changes to the Tokamak cooling water system design have enhanced confinement and reduced potential radiological releases as well as removing decay heat with very high reliability. New and updated accident scenario analyses, together with fire and explosion risk analyses, have shown that design provisions are sufficient to minimize the likelihood of accidents and reduce potential consequences to a very low level. Taken together, the improvements provided a stronger demonstration of the very good safety performance of the ITER design.

  18. Updated safety analysis of ITER

    International Nuclear Information System (INIS)

    Taylor, Neill; Baker, Dennis; Ciattaglia, Sergio; Cortes, Pierre; Elbez-Uzan, Joelle; Iseli, Markus; Reyes, Susana; Rodriguez-Rodrigo, Lina; Rosanvallon, Sandrine; Topilski, Leonid

    2011-01-01

    An updated version of the ITER Preliminary Safety Report has been produced and submitted to the licensing authorities. It is revised and expanded in response to requests from the authorities after their review of an earlier version in 2008, to reflect enhancements in ITER safety provisions through design changes, to incorporate new and improved safety analyses and to take into account other ITER design evolution. The updated analyses show that changes to the Tokamak cooling water system design have enhanced confinement and reduced potential radiological releases as well as removing decay heat with very high reliability. New and updated accident scenario analyses, together with fire and explosion risk analyses, have shown that design provisions are sufficient to minimize the likelihood of accidents and reduce potential consequences to a very low level. Taken together, the improvements provided a stronger demonstration of the very good safety performance of the ITER design.

  19. Mining Sequential Update Summarization with Hierarchical Text Analysis

    Directory of Open Access Journals (Sweden)

    Chunyun Zhang

    2016-01-01

    Full Text Available The outbreak of unexpected news events such as large human accident or natural disaster brings about a new information access problem where traditional approaches fail. Mostly, news of these events shows characteristics that are early sparse and later redundant. Hence, it is very important to get updates and provide individuals with timely and important information of these incidents during their development, especially when being applied in wireless and mobile Internet of Things (IoT. In this paper, we define the problem of sequential update summarization extraction and present a new hierarchical update mining system which can broadcast with useful, new, and timely sentence-length updates about a developing event. The new system proposes a novel method, which incorporates techniques from topic-level and sentence-level summarization. To evaluate the performance of the proposed system, we apply it to the task of sequential update summarization of temporal summarization (TS track at Text Retrieval Conference (TREC 2013 to compute four measurements of the update mining system: the expected gain, expected latency gain, comprehensiveness, and latency comprehensiveness. Experimental results show that our proposed method has good performance.

  20. Run-time Phenomena in Dynamic Software Updating: Causes and Effects

    DEFF Research Database (Denmark)

    Gregersen, Allan Raundahl; Jørgensen, Bo Nørregaard

    2011-01-01

    The development of a dynamic software updating system for statically-typed object-oriented programming languages has turned out to be a challenging task. Despite the fact that the present state of the art in dynamic updating systems, like JRebel, Dynamic Code Evolution VM, JVolve and Javeleon, all...... written in statically-typed object-oriented programming languages. In this paper, we present our experience from developing dynamically updatable applications using a state-of-the-art dynamic updating system for Java. We believe that the findings presented in this paper provide an important step towards...... provide very transparent and flexible technical solutions to dynamic updating, case studies have shown that designing dynamically updatable applications still remains a challenging task. This challenge has its roots in a number of run-time phenomena that are inherent to dynamic updating of applications...

  1. 34 CFR 668.55 - Updating information.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false Updating information. 668.55 Section 668.55 Education... Information § 668.55 Updating information. (a)(1) Unless the provisions of paragraph (a)(2) or (a)(3) of this... applicant to verify the information contained in his or her application for assistance in an award year if...

  2. JOYO MK-II core characteristics database. Update to JFS-3-J3.2R

    International Nuclear Information System (INIS)

    Ohkawachi, Yasushi; Maeda, Shigetaka; Sekine, Takashi

    2003-04-01

    The 'JOYO' MK-II core characteristics database was compiled and published in 1998. Comments and requests from many users led to the creation of a revised edition in 2001. The revisions include changes to the MAGI calculation code system to use the 70 group JFS-3-J3.2 constant set processed from the JENDL-3.2 library. However, after the database was published, it was recently found that there were errors in the process of making the group constant set JFS-3-J3.2, and it was revised at JFS-3-J3.2R. Then, the group constant set was updated at JFS-3-J3.2R in this database. The MK-II core management data nad core characteristics data were recorded on CD-ROM for user convenience. The structure of the database is the same as in the first edition. The 'Configuration Data' include the core arrangement and refueling record for each operational cycle. The 'Subassembly Library Data' include the atomic number density, neutron fluence, burn-up, integral power of 362 driver fuel subassemblies and 69 irradiation test subassemblies. The 'Output Data' contain the calculated neutron flux, gamma flux, power density, linear heat rate, coolant and fuel temperature distribution of all the fuel subassemblies at the beginning and end of each operational cycle. The 'Core Characteristics Data' include the measured excess reactivity, control rod worth calibration curve, and reactivity coefficients of temperature, power and burn-up. The effect of updating the group constant set, the calculation results of excess reactivity decreased by about 0.15Δk/kk', and the effects to other core characteristics were negligible. (author)

  3. Fentanyl Formulations in the Management of Pain: An Update.

    Science.gov (United States)

    Schug, Stephan A; Ting, Sonya

    2017-05-01

    Fentanyl is a synthetic, highly selective opioid with many desirable physicochemical properties, including a high lipophilicity and predictable pharmacokinetics. These properties have an established record in the management of pain in a variety of settings, particularly acute pain and breakthrough cancer pain. Fentanyl was initially developed for parenteral use; however, this is invasive and impractical in the outpatient setting. Unfortunately, the high first-pass metabolism of fentanyl makes oral formulations unfeasible. However, its high lipophilicity allows fentanyl to be absorbed via a number of other routes. Thus new formulations were designed to allow non-invasive methods of administration. Transmucosal and transdermal fentanyl formulations are well established, and have proven useful in the settings of breakthrough cancer pain, emergencies and in the paediatric population. The iontophoretic transdermal system was developed to provide a needle-free system of delivering bolus doses of fentanyl on demand, a novel way of delivering patient-controlled opioid analgesia. Transpulmonary administration of fentanyl remains experimental. The aim of this review is to provide an update on current non-parenteral fentanyl formulations, with attention to their particular pharmacokinetics and features relevant to clinical use in pain management.

  4. Interaction Support for the Global Fluxnet Data Set

    Science.gov (United States)

    Agarwal, D.; Humphrey, M.; Beekwilder, N.; Goode, M.; Jackson, K.; Weber, R.; van Ingen, C.; Baldocchi, D.

    2008-12-01

    The FLUXNET synthesis data set contains on the order of 960 site-years of sensor data from over 260 sites around the world. This is a living data set; a data update this year should add new site-years from over 200 sites. The data are the ground truth for carbon-climate studies linking models and remote sensing as well as comparative field analyses. Over 65 synthesis teams are using this data to do global and regional scale analyses. The size of the dataset makes browsing the data difficult; for example, a search of the dataset for sites with particular meteorological characteristics would require a download of the complete dataset and then running all of the data through a preliminary analysis. Synthesis studies often need additional non- sensor measurements such as root biomass, soil composition, or fire occurrence; some of these variables require detailed knowledge of the site and the science. The large number of sites makes the assembly, cleaning, and long term curation of the non-sensor data daunting; a virtual conversation between the data providers, data users, and data curators is needed. The large number of sites also makes tracking updates to the site information and communicating with site PIs difficult for synthesis study teams. We have developed a collaborative web portal which enables data browsing on line, orchestrates the data curation virtual conversation, and enables the synthesis team conversation with sites. Behind the portal is an archive database and OLAP data cube for simple data browsing through query. Scientists can download data files, browse data summaries, update metadata and annotate the data through the portal. Synthesis teams can select sites and exchange e-mail with those sites through the portal. The data can also be browsed directly from Excel spreadsheets or MatLab from the scientist desktop; the scientist sees no difference between data "in the cloud" and on the desktop. We believe the portal enables science researchers to

  5. Working memory updating occurs independently of the need to maintain task-context: accounting for triggering updating in the AX-CPT paradigm.

    Science.gov (United States)

    Kessler, Yoav; Baruchin, Liad J; Bouhsira-Sabag, Anat

    2017-01-01

    Theoretical models suggest that maintenance and updating are two functional states of working memory (WM), which are controlled by a gate between perceptual information and WM representations. Opening the gate enables updating WM with input, while closing it enables keeping the maintained information shielded from interference. However, it is still unclear when gate opening takes place, and what is the external signal that triggers it. A version of the AX-CPT paradigm was used to examine a recent proposal in the literature, suggesting that updating is triggered whenever the maintenance of the context is necessary for task performance (context-dependent tasks). In four experiments using this paradigm, we show that (1) a task-switching cost takes place in both context-dependent and context-independent trials; (2) task-switching is additive to the dependency effect, and (3) unlike switching cost, the dependency effect is not affected by preparation and, therefore, does not reflect context-updating. We suggest that WM updating is likely to be triggered by a simple mechanism that occurs in each trial of the task regardless of whether maintaining the context is needed or not. The implications for WM updating and its relationship to task-switching are discussed.

  6. Paternidade no Brasil: revisão sistemática de artigos empíricos

    Directory of Open Access Journals (Sweden)

    Mauro Luís Vieira

    2014-01-01

    Full Text Available El objetivo del estudio fue caracterizar la producción de artículos empíricos rela - cionados con el tema de la paternidad y su contribución al desarrollo del niño y de la familia, publicados entre 2000 y 2012 en revistas brasileñas indexadas en bases de datos IndexPsi, SciELO y PePSIC. Los descriptores usados fueron: “padre”, “paternidad” y “paternal”. Un centenar de artículos fueron analizados en su totalidad. En el 70% de ellos, los autores utilizaron el análisis cualitativo de los datos. Se observó la preferencia por el método de recolección de datos (60% y por la entrevista como técnica de recogida (47%. Entre los temas investigados se destacan: embarazo, parto y puerperio (25%, el ejercicio de la paternidad (22%, el desarrollo del niño (15%, la adolescencia (14% y concep - tos sobre el comportamiento paternal (13%. Estudios futuros deben investigar al padre en diferentes contextos y la división de papeles en la familia, la inte - gración de los enfoques cuantitativos y cualitativos y los estudios longitudinales.

  7. Test Series 4: seismic-fragility tests of naturally-aged Exide EMP-13 battery cells

    International Nuclear Information System (INIS)

    Bonzon, L.L.; Hente, D.B.; Kukreti, B.M.; Schendel, J.; Tulk, J.D.; Janis, W.J.; Black, D.A.; Paulsen, G.D.; Aucoin, B.D.

    1985-03-01

    This report, the fourth in a test series of an extensive seismic research program, covers the testing of a 27-year old lead-antimony Exide EMP-13 cells from the recently decommissioned Shippingport Atomic Power Station. The Exide cells were tested in two configurations using a triaxial shake table: single-cell tests, rigidly mounted; and multicell (five-cell) tests, mounted in a typical battery rack. A total of nine electrically active cells was used in the two different cell configurations. None of the nine cells failed during the actual seismic tests when a range of ZPAs up to 1.5 g was imposed. Subsequent discharge capacity tests of five of the cells showed, however, that none of the cells could deliver the accepted standard of 80% of their rated electrical capacity for 3 hours. In fact, none of the 5 cells could deliver more than a 33% capacity. Two of the seismically tested cells and one untested, low capacity cell were disassembled for examination and metallurgical analyses. The inspection showed the cells to be in poor condition. The negative plates in the vicinity of the bus connections were extremely weak, the positive buses were corroded and brittle, negative and positive active material utilization was extremely uneven, and corrosion products littered the cells

  8. Numerical model updating technique for structures using firefly algorithm

    Science.gov (United States)

    Sai Kubair, K.; Mohan, S. C.

    2018-03-01

    Numerical model updating is a technique used for updating the existing experimental models for any structures related to civil, mechanical, automobiles, marine, aerospace engineering, etc. The basic concept behind this technique is updating the numerical models to closely match with experimental data obtained from real or prototype test structures. The present work involves the development of numerical model using MATLAB as a computational tool and with mathematical equations that define the experimental model. Firefly algorithm is used as an optimization tool in this study. In this updating process a response parameter of the structure has to be chosen, which helps to correlate the numerical model developed with the experimental results obtained. The variables for the updating can be either material or geometrical properties of the model or both. In this study, to verify the proposed technique, a cantilever beam is analyzed for its tip deflection and a space frame has been analyzed for its natural frequencies. Both the models are updated with their respective response values obtained from experimental results. The numerical results after updating show that there is a close relationship that can be brought between the experimental and the numerical models.

  9. Update of European bioethics

    DEFF Research Database (Denmark)

    Rendtorff, Jacob Dahl

    2015-01-01

    This paper presents an update of the research on European bioethics undertaken by the author together with Professor Peter Kemp since the 1990s, on Basic ethical principles in European bioethics and biolaw. In this European approach to basic ethical principles in bioethics and biolaw......, the principles of autonomy, dignity, integrity and vulnerability are proposed as the most important ethical principles for respect for the human person in biomedical and biotechnological development. This approach to bioethics and biolaw is presented here in a short updated version that integrates the earlier...... research in a presentation of the present understanding of the basic ethical principles in bioethics and biolaw....

  10. Updates on the Performance and Calibration of HST/STIS

    Science.gov (United States)

    Lockwood, Sean A.; Monroe, TalaWanda R.; Ogaz, Sara; Branton, Doug; Carlberg, Joleen K.; Debes, John H.; Jedrzejewski, Robert I.; Proffitt, Charles R.; Riley, Allyssa; Sohn, Sangmo Tony; Sonnentrucker, Paule; Walborn, Nolan R.; Welty, Daniel

    2018-06-01

    The Space Telescope Imaging Spectrograph (STIS) on the Hubble Space Telescope (HST) has been in orbit for 21 years and continues to produce high quality scientific results using a diverse complement of operating modes. These include spatially resolved spectroscopy in the UV and optical, high spatial resolution echelle spectroscopy in the UV, and solar-blind imaging in the UV. In addition, STIS possesses unique visible-light coronagraphic modes that keep the instrument at the forefront of exoplanet and debris-disk research. As the instrument's characteristics evolve over its lifetime, the instrument team at the Space Telescope Science Institute monitors its performance and works towards improving the quality of its data products. Here we present updates on the status of the STIS CCD and FUV & NUV MAMA detectors, as well as changes to the CalSTIS reduction pipeline. We also discuss progress toward the recalibration of the E140M/1425 echelle mode. The E140M grating blaze function shapes have changed since flux calibration was carried out following SM4, which limits the relative photometric flux accuracy of some spectral orders up to 5-10% at the edges. In Cycle 25 a special calibration program was executed to obtain updated sensitivity curves for the E140M/1425 setting.

  11. Robot Visual Tracking via Incremental Self-Updating of Appearance Model

    Directory of Open Access Journals (Sweden)

    Danpei Zhao

    2013-09-01

    Full Text Available This paper proposes a target tracking method called Incremental Self-Updating Visual Tracking for robot platforms. Our tracker treats the tracking problem as a binary classification: the target and the background. The greyscale, HOG and LBP features are used in this work to represent the target and are integrated into a particle filter framework. To track the target over long time sequences, the tracker has to update its model to follow the most recent target. In order to deal with the problems of calculation waste and lack of model-updating strategy with the traditional methods, an intelligent and effective online self-updating strategy is devised to choose the optimal update opportunity. The strategy of updating the appearance model can be achieved based on the change in the discriminative capability between the current frame and the previous updated frame. By adjusting the update step adaptively, severe waste of calculation time for needless updates can be avoided while keeping the stability of the model. Moreover, the appearance model can be kept away from serious drift problems when the target undergoes temporary occlusion. The experimental results show that the proposed tracker can achieve robust and efficient performance in several benchmark-challenging video sequences with various complex environment changes in posture, scale, illumination and occlusion.

  12. Decentralized Consistent Network Updates in SDN with ez-Segway

    KAUST Repository

    Nguyen, Thanh Dang

    2017-03-06

    We present ez-Segway, a decentralized mechanism to consistently and quickly update the network state while preventing forwarding anomalies (loops and black-holes) and avoiding link congestion. In our design, the centralized SDN controller only pre-computes information needed by the switches during the update execution. This information is distributed to the switches, which use partial knowledge and direct message passing to efficiently realize the update. This separation of concerns has the key benefit of improving update performance as the communication and computation bottlenecks at the controller are removed. Our evaluations via network emulations and large-scale simulations demonstrate the efficiency of ez-Segway, which compared to a centralized approach, improves network update times by up to 45% and 57% at the median and the 99th percentile, respectively. A deployment of a system prototype in a real OpenFlow switch and an implementation in P4 demonstrate the feasibility and low overhead of implementing simple network update functionality within switches.

  13. Infection Prevention and Control in Pediatric Ambulatory Settings.

    Science.gov (United States)

    Rathore, Mobeen H; Jackson, Mary Anne

    2017-11-01

    Since the American Academy of Pediatrics published its statement titled "Infection Prevention and Control in Pediatric Ambulatory Settings" in 2007, there have been significant changes that prompted this updated statement. Infection prevention and control is an integral part of pediatric practice in ambulatory medical settings as well as in hospitals. Infection prevention and control practices should begin at the time the ambulatory visit is scheduled. All health care personnel should be educated regarding the routes of transmission and techniques used to prevent the transmission of infectious agents. Policies for infection prevention and control should be written, readily available, updated every 2 years, and enforced. Many of the recommendations for infection control and prevention from the Centers for Disease Control and Prevention for hospitalized patients are also applicable in the ambulatory setting. These recommendations include requirements for pediatricians to take precautions to identify and protect employees likely to be exposed to blood or other potentially infectious materials while on the job. In addition to emphasizing the key principles of infection prevention and control in this policy, we update those that are relevant to the ambulatory care patient. These guidelines emphasize the role of hand hygiene and the implementation of diagnosis- and syndrome-specific isolation precautions, with the exemption of the use of gloves for routine diaper changes and wiping a well child's nose or tears for most patient encounters. Additional topics include respiratory hygiene and cough etiquette strategies for patients with a respiratory tract infection, including those relevant for special populations like patients with cystic fibrosis or those in short-term residential facilities; separation of infected, contagious children from uninfected children when feasible; safe handling and disposal of needles and other sharp medical devices; appropriate use of personal

  14. Minnesota's forest statistics, 1987: an inventory update.

    Science.gov (United States)

    Jerold T. Hahn; W. Brad Smith

    1987-01-01

    The Minnesota 1987 inventory update, derived by using tree growth models, reports 13.5 million acres of timberland, a decline of less than 1% since 1977. This bulletin presents findings from the inventory update in tables detailing timer land area, volume, and biomass.

  15. Wisconsin's forest statistics, 1987: an inventory update.

    Science.gov (United States)

    W. Brad Smith; Jerold T. Hahn

    1989-01-01

    The Wisconsin 1987 inventory update, derived by using tree growth models, reports 14.7 million acres of timberland, a decline of less than 1% since 1983. This bulletin presents findings from the inventory update in tables detailing timberland area, volume, and biomass.

  16. Research on Topographic Map Updating

    Directory of Open Access Journals (Sweden)

    Ivana Javorović

    2013-04-01

    Full Text Available The investigation of interpretability of panchromatic satellite image IRS-1C integrated with multispectral Landsat TM image with the purpose of updating the topographic map sheet at the scale of 1:25 000 has been described. The geocoding of source map was based on trigonometric points of the map sheet. Satellite images were geocoded using control points selected from the map. The contents of map have been vectorized and topographic database designed. The digital image processing improved the interpretability of images. Then, the vectorization of new contents was made. The change detection of the forest and water area was defined by using unsupervised classification of spatial and spectral merged images. Verification of the results was made using corresponding aerial photographs. Although this methodology could not insure the complete updating of topographic map at the scale of 1:25 000, the database has been updated with huge amount of data. Erdas Imagine 8.3. software was used. 

  17. Strategies, Protections and Mitigations for Electric Grid from Electromagnetic Pulse Effects

    Energy Technology Data Exchange (ETDEWEB)

    Foster, Rita Ann [Idaho National Lab. (INL), Idaho Falls, ID (United States); Frickey, Steven Jay [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-01-01

    The mission of DOE’s Office of Electricity Delivery and Energy Reliability (OE) is to lead national efforts to modernize the electricity delivery system, enhance the security and reliability of America’s energy infrastructure and facilitate recovery from disruptions to the energy supply. One of the threats OE is concerned about is a high-altitude electro-magnetic pulse (HEMP) from a nuclear explosion and eletro-magnetic pulse (EMP) or E1 pulse can be generated by EMP weapons. DOE-OE provides federal leadership and technical guidance in addressing electric grid issues. The Idaho National Laboratory (INL) was chosen to conduct the EMP study for DOE-OE due to its capabilities and experience in setting up EMP experiments on the electric grid and conducting vulnerability assessments and developing innovative technology to increase infrastructure resiliency. This report identifies known impacts to EMP threats, known mitigations and effectiveness of mitigations, potential cost of mitigation, areas for government and private partnerships in protecting the electric grid to EMP, and identifying gaps in our knowledge and protection strategies.

  18. Fusion strategies for selecting multiple tuning parameters for multivariate calibration and other penalty based processes: A model updating application for pharmaceutical analysis

    Energy Technology Data Exchange (ETDEWEB)

    Tencate, Alister J. [Department of Chemistry, Idaho State University, Pocatello, ID 83209 (United States); Kalivas, John H., E-mail: kalijohn@isu.edu [Department of Chemistry, Idaho State University, Pocatello, ID 83209 (United States); White, Alexander J. [Department of Physics and Optical Engineering, Rose-Hulman Institute of Technology, Terre Huate, IN 47803 (United States)

    2016-05-19

    New multivariate calibration methods and other processes are being developed that require selection of multiple tuning parameter (penalty) values to form the final model. With one or more tuning parameters, using only one measure of model quality to select final tuning parameter values is not sufficient. Optimization of several model quality measures is challenging. Thus, three fusion ranking methods are investigated for simultaneous assessment of multiple measures of model quality for selecting tuning parameter values. One is a supervised learning fusion rule named sum of ranking differences (SRD). The other two are non-supervised learning processes based on the sum and median operations. The effect of the number of models evaluated on the three fusion rules are also evaluated using three procedures. One procedure uses all models from all possible combinations of the tuning parameters. To reduce the number of models evaluated, an iterative process (only applicable to SRD) is applied and thresholding a model quality measure before applying the fusion rules is also used. A near infrared pharmaceutical data set requiring model updating is used to evaluate the three fusion rules. In this case, calibration of the primary conditions is for the active pharmaceutical ingredient (API) of tablets produced in a laboratory. The secondary conditions for calibration updating is for tablets produced in the full batch setting. Two model updating processes requiring selection of two unique tuning parameter values are studied. One is based on Tikhonov regularization (TR) and the other is a variation of partial least squares (PLS). The three fusion methods are shown to provide equivalent and acceptable results allowing automatic selection of the tuning parameter values. Best tuning parameter values are selected when model quality measures used with the fusion rules are for the small secondary sample set used to form the updated models. In this model updating situation, evaluation of

  19. Fusion strategies for selecting multiple tuning parameters for multivariate calibration and other penalty based processes: A model updating application for pharmaceutical analysis

    International Nuclear Information System (INIS)

    Tencate, Alister J.; Kalivas, John H.; White, Alexander J.

    2016-01-01

    New multivariate calibration methods and other processes are being developed that require selection of multiple tuning parameter (penalty) values to form the final model. With one or more tuning parameters, using only one measure of model quality to select final tuning parameter values is not sufficient. Optimization of several model quality measures is challenging. Thus, three fusion ranking methods are investigated for simultaneous assessment of multiple measures of model quality for selecting tuning parameter values. One is a supervised learning fusion rule named sum of ranking differences (SRD). The other two are non-supervised learning processes based on the sum and median operations. The effect of the number of models evaluated on the three fusion rules are also evaluated using three procedures. One procedure uses all models from all possible combinations of the tuning parameters. To reduce the number of models evaluated, an iterative process (only applicable to SRD) is applied and thresholding a model quality measure before applying the fusion rules is also used. A near infrared pharmaceutical data set requiring model updating is used to evaluate the three fusion rules. In this case, calibration of the primary conditions is for the active pharmaceutical ingredient (API) of tablets produced in a laboratory. The secondary conditions for calibration updating is for tablets produced in the full batch setting. Two model updating processes requiring selection of two unique tuning parameter values are studied. One is based on Tikhonov regularization (TR) and the other is a variation of partial least squares (PLS). The three fusion methods are shown to provide equivalent and acceptable results allowing automatic selection of the tuning parameter values. Best tuning parameter values are selected when model quality measures used with the fusion rules are for the small secondary sample set used to form the updated models. In this model updating situation, evaluation of

  20. MO-AB-207-03: ACR Update in Nuclear Medicine

    International Nuclear Information System (INIS)

    Harkness, B.

    2015-01-01

    A goal of an imaging accreditation program is to ensure adequate image quality, verify appropriate staff qualifications, and to assure patient and personnel safety. Currently, more than 35,000 facilities in 10 modalities have been accredited by the American College of Radiology (ACR), making the ACR program one of the most prolific accreditation options in the U.S. In addition, ACR is one of the accepted accreditations required by some state laws, CMS/MIPPA insurance and others. Familiarity with the ACR accreditation process is therefore essential to clinical diagnostic medical physicists. Maintaining sufficient knowledge of the ACR program must include keeping up-to-date as the various modality requirements are refined to better serve the goals of the program and to accommodate newer technologies and practices. This session consists of presentations from authorities in four ACR accreditation modality programs, including magnetic resonance imaging, computed tomography, nuclear medicine, and mammography. Each speaker will discuss the general components of the modality program and address any recent changes to the requirements. Learning Objectives: To understand the requirements of the ACR MR Accreditation program. The discussion will include accreditation of whole-body general purpose magnets, dedicated extremity systems well as breast MRI accreditation. Anticipated updates to the ACR MRI Quality Control Manual will also be reviewed. To understand the requirements of the ACR CT accreditation program, including updates to the QC manual as well as updates through the FAQ process. To understand the requirements of the ACR nuclear medicine accreditation program, and the role of the physicist in annual equipment surveys and the set up and supervision of the routine QC program. To understand the current ACR MAP Accreditation requirement and present the concepts and structure of the forthcoming ACR Digital Mammography QC Manual and Program

  1. MO-AB-207-03: ACR Update in Nuclear Medicine

    Energy Technology Data Exchange (ETDEWEB)

    Harkness, B. [Henry Ford Hospital System (United States)

    2015-06-15

    A goal of an imaging accreditation program is to ensure adequate image quality, verify appropriate staff qualifications, and to assure patient and personnel safety. Currently, more than 35,000 facilities in 10 modalities have been accredited by the American College of Radiology (ACR), making the ACR program one of the most prolific accreditation options in the U.S. In addition, ACR is one of the accepted accreditations required by some state laws, CMS/MIPPA insurance and others. Familiarity with the ACR accreditation process is therefore essential to clinical diagnostic medical physicists. Maintaining sufficient knowledge of the ACR program must include keeping up-to-date as the various modality requirements are refined to better serve the goals of the program and to accommodate newer technologies and practices. This session consists of presentations from authorities in four ACR accreditation modality programs, including magnetic resonance imaging, computed tomography, nuclear medicine, and mammography. Each speaker will discuss the general components of the modality program and address any recent changes to the requirements. Learning Objectives: To understand the requirements of the ACR MR Accreditation program. The discussion will include accreditation of whole-body general purpose magnets, dedicated extremity systems well as breast MRI accreditation. Anticipated updates to the ACR MRI Quality Control Manual will also be reviewed. To understand the requirements of the ACR CT accreditation program, including updates to the QC manual as well as updates through the FAQ process. To understand the requirements of the ACR nuclear medicine accreditation program, and the role of the physicist in annual equipment surveys and the set up and supervision of the routine QC program. To understand the current ACR MAP Accreditation requirement and present the concepts and structure of the forthcoming ACR Digital Mammography QC Manual and Program.

  2. Software Updating in Wireless Sensor Networks: A Survey and Lacunae

    Directory of Open Access Journals (Sweden)

    Cormac J. Sreenan

    2013-11-01

    Full Text Available Wireless Sensor Networks are moving out of the laboratory and into the field. For a number of reasons there is often a need to update sensor node software, or node configuration, after deployment. The need for over-the-air updates is driven both by the scale of deployments, and by the remoteness and inaccessibility of sensor nodes. This need has been recognized since the early days of sensor networks, and research results from the related areas of mobile networking and distributed systems have been applied to this area. In order to avoid any manual intervention, the update process needs to be autonomous. This paper presents a comprehensive survey of software updating in Wireless Sensor Networks, and analyses the features required to make these updates autonomous. A new taxonomy of software update features and a new model for fault detection and recovery are presented. The paper concludes by identifying the lacunae relating to autonomous software updates, providing direction for future research.

  3. 77 FR 41258 - FOIA Fee Schedule Update

    Science.gov (United States)

    2012-07-13

    ... DEFENSE NUCLEAR FACILITIES SAFETY BOARD 10 CFR Part 1703 FOIA Fee Schedule Update AGENCY: Defense Nuclear Facilities Safety Board. ACTION: Establishment of FOIA Fee Schedule. SUMMARY: The Defense Nuclear Facilities Safety Board is publishing its Freedom of Information Act (FOIA) Fee Schedule Update pursuant to...

  4. 76 FR 43819 - FOIA Fee Schedule Update

    Science.gov (United States)

    2011-07-22

    ... DEFENSE NUCLEAR FACILITIES SAFETY BOARD 10 CFR Part 1703 FOIA Fee Schedule Update AGENCY: Defense Nuclear Facilities Safety Board. ACTION: Establishment of FOIA Fee Schedule. SUMMARY: The Defense Nuclear Facilities Safety Board is publishing its Freedom of Information Act (FOIA) Fee Schedule Update pursuant to...

  5. Una Evaluación Empírica del Fondo de Comercio

    Directory of Open Access Journals (Sweden)

    Manuel Larrán Jorge

    2000-06-01

    Full Text Available En el presente trabajo se analizará bajo una perspectiva empírica uno de los activos empresariales más controvertidos como es el fondo de comercio. Dicha controversia no se materializa únicamente en su definición, sino también en su cuantificación y tratamiento contable, dando lugar en los últimos años a una importante línea de investigación centrada en la relevancia valorativa del fondo de comercio en particular y de los intangibles en general. Nuestro trabajo plantea un doble objetivo: en primer lugar, estudiar los efectos económicos ocasionados por tratamientos contables alternativos del fondo de comercio, mediante el análisis de la sensibilidad de determinados ratios ante las diversas opciones contables existentes; y, en segundo término, verificar la relevancia valorativa del fondo de comercio desde la perspectiva del mercado de capitales. Para la realización del trabajo hemos utilizado información contable de grupos de empresas españoles e información bursátil correspondiente a la dominante para los ejercicios 1991-1997.Las conclusiones básicas obtenidas se centran en que el análisis empresarial basado en ratios puede verse afectado por el tratamiento contable a que se haya sometido al fondo de comercio. Por otra parte, se obtienen evidencias del incremento en el tiempo de la relevancia valorativa del fondo de comercio en el mercado bursátil español, así como de la dependencia de dicha relevancia de ciertos factores contextuales como el nivel de resultados, la participación del fondo de comercio en el total de activo, etc. This paper analyses from an empirical perspective one of the most controversial of company assets, namely goodwill. The controversial nature of goodwill lies not only in its definition but also in its quantification and accounting treatment, giving rise in recent years to an important line of research centred on the value relevance of goodwill in particular and intangibles in general.The paper has

  6. Measuring Child Poverty in South Africa: Sensitivity to the Choice of Equivalence Scale and an Updated Profile

    Science.gov (United States)

    Streak, Judith Christine; Yu, Derek; Van der Berg, Servaas

    2009-01-01

    This paper offers evidence on the sensitivity of child poverty in South Africa to changes in the adult equivalence scale (AES) and updates the child poverty profile based on the Income and Expenditure Survey 2005/06. Setting the poverty line at the 40th percentile of households calculated with different AESs the scope and composition of child…

  7. Environmental Regulatory Update Table, December 1989

    International Nuclear Information System (INIS)

    Houlbert, L.M.; Langston, M.E.; Nikbakht, A.; Salk, M.S.

    1990-01-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action

  8. Environmental regulatory update table, March 1989

    International Nuclear Information System (INIS)

    Houlberg, L.; Langston, M.E.; Nikbakht, A.; Salk, M.S.

    1989-04-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action

  9. Environmental Regulatory Update Table, April 1989

    International Nuclear Information System (INIS)

    Houlberg, L.; Langston, M.E.; Nikbakht, A.; Salk, M.S.

    1989-05-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action

  10. Environmental Regulatory Update Table, December 1991

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.

    1992-01-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  11. Environmental Regulatory Update Table, August 1990

    International Nuclear Information System (INIS)

    Houlberg, L.M.; Nikbakht, A.; Salk, M.S.

    1990-09-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action

  12. Environmental Regulatory Update Table, October 1991

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.

    1991-11-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  13. Environmental Regulatory Update Table, November 1991

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.

    1991-12-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  14. Environmental Regulatory Update Table, September 1991

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.

    1991-10-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  15. How Do We Update Faces? Effects of Gaze Direction and Facial Expressions on Working Memory Updating

    OpenAIRE

    Artuso, Caterina; Palladino, Paola; Ricciardelli, Paola

    2012-01-01

    The aim of the study was to investigate how the biological binding between different facial dimensions, and their social and communicative relevance, may impact updating processes in working memory (WM). We focused on WM updating because it plays a key role in ongoing processing. Gaze direction and facial expression are crucial and changeable components of face processing. Direct gaze enhances the processing of approach-oriented facial emotional expressions (e.g., joy), while averted gaze enh...

  16. Updating river basin models with radar altimetry

    DEFF Research Database (Denmark)

    Michailovsky, Claire Irene B.

    suited for use in data assimilation frameworks which combine the information content from models and current observations to produce improved forecasts and reduce prediction uncertainty. The focus of the second and third papers of this thesis was therefore the use of radar altimetry as update data...... of political unwillingness to share data which is a common problem in particular in transboundary settings. In this context, remote sensing (RS) datasets provide an appealing alternative to traditional in-situ data and much research effort has gone into the use of these datasets for hydrological applications...... response of a catchment to meteorological forcing. While river discharge cannot be directly measured from space, radar altimetry (RA) can measure water level variations in rivers at the locations where the satellite ground track and river network intersect called virtual stations or VS. In this PhD study...

  17. Project SAFE. Update of the SFR-1 safety assessment. Phase 1. Appendix A4: Far-field

    International Nuclear Information System (INIS)

    Follin, S.; Andersson, Johan; Holmen, J.; Axelsson, C.L.

    1998-01-01

    This appendix has identified potential needs for updated hydrogeological modelling of the SFR in connection to the planned update of the performance assessment of the SFR within the framework of the SAFE-project. The objectives of such updated modelling should be to present a credible representation of the hydrogeological system, to explore effects of seals and repository extensions and to provide input to the release and transport calculations of the assessment. The last objective has led to the conclusion that an important focus of the modelling should be to determine the flow through the vaults under different conditions as this flow appear to be a very important quantity in the radionuclide release calculations. The suggested modelling should use relevant data and apply modern modelling tools and techniques, but should be geared towards the objectives. For this reasons it is suggested to apply a set of complementary and sometimes nested approaches, where each model approach is set up in order to address a specific set of questions. Answering these questions would motivate simplifications made in subsequent steps of the modelling. To the extent possible the models should be compared with existing data on flow and Baltic water breakthrough. However, in making such comparisons the accuracy of the measurements and the precision of the models need to be considered. A one-to-one match cannot be expected. It appears that careful geochemical evaluation of the site would only be necessary if more credit is placed on migration in the geosphere. If such an evaluation is considered it should be co-ordinated with the regional groundwater modelling. The issue of gas production should be reconsidered in a scenario and process analysis of SFR. However, given the strong conclusions already made it appears that gas migration in the rock will still remain as a minor issue. The major assumptions going into the analysis of the near-field in the final safety report and the deepened

  18. Updating sea spray aerosol emissions in the Community Multiscale Air Quality (CMAQ) model version 5.0.2

    Science.gov (United States)

    Gantt, B.; Kelly, J. T.; Bash, J. O.

    2015-11-01

    Sea spray aerosols (SSAs) impact the particle mass concentration and gas-particle partitioning in coastal environments, with implications for human and ecosystem health. Model evaluations of SSA emissions have mainly focused on the global scale, but regional-scale evaluations are also important due to the localized impact of SSAs on atmospheric chemistry near the coast. In this study, SSA emissions in the Community Multiscale Air Quality (CMAQ) model were updated to enhance the fine-mode size distribution, include sea surface temperature (SST) dependency, and reduce surf-enhanced emissions. Predictions from the updated CMAQ model and those of the previous release version, CMAQv5.0.2, were evaluated using several coastal and national observational data sets in the continental US. The updated emissions generally reduced model underestimates of sodium, chloride, and nitrate surface concentrations for coastal sites in the Bay Regional Atmospheric Chemistry Experiment (BRACE) near Tampa, Florida. Including SST dependency to the SSA emission parameterization led to increased sodium concentrations in the southeastern US and decreased concentrations along parts of the Pacific coast and northeastern US. The influence of sodium on the gas-particle partitioning of nitrate resulted in higher nitrate particle concentrations in many coastal urban areas due to increased condensation of nitric acid in the updated simulations, potentially affecting the predicted nitrogen deposition in sensitive ecosystems. Application of the updated SSA emissions to the California Research at the Nexus of Air Quality and Climate Change (CalNex) study period resulted in a modest improvement in the predicted surface concentration of sodium and nitrate at several central and southern California coastal sites. This update of SSA emissions enabled a more realistic simulation of the atmospheric chemistry in coastal environments where marine air mixes with urban pollution.

  19. Apology in the Criminal Justice Setting: An Update

    Directory of Open Access Journals (Sweden)

    Carrie Petrucci

    2017-08-01

    Full Text Available Apology has many benefits to offenders and victims. The last 15 years have produced worthwhile quantitative and qualitative studies that have refined our understanding of apology, but have also identified the diversity in what can be said in apology and how it can be received. The apology literature in the last 15 years in social psychology, criminology, and criminal justice is examined, including two and three-way interaction effects and qualitative results that focus on the effectiveness of apology at the contextual and individual levels, and the important role that emotion can play. It is recommended that apology be implemented with a “less is more” approach for apology to be most effective for youth in juvenile justice; and that a venue is provided for a spontaneous/voluntary apology to occur, or a minimally prepared apology, using only broad prescriptions on how it ought to be carried out. By utilizing appropriate research strategies, knowledge about apology and its effectiveness in legal settings including juvenile justice can continue to build to determine what type of apology works best for whom under what circumstances.Las disculpas tienen numerosos beneficios para víctimas y victimarios. En los últimos 15 años se han realizado importantes estudios cuantitativos y cualitativos que han mejorado nuestra comprensión sobre las disculpas, pero que también han identificado la diversidad de lo que se puede decir al pedir perdón y cómo se puede recibir. Se analiza la literatura sobre disculpas de los últimos 15 años en la psicología social, la criminología, y la justicia penal, incluyendo efectos de interacción de dos y tres vías que se centran en la efectividad de las disculpas en los niveles contextual e individual, y el rol tan importante que puede jugar la emoción. Se recomienda que la disculpa se desarrolle bajo un acercamiento de "menos es más" para que sea más efectiva en el caso de los jóvenes en la justicia juvenil

  20. Environmental Regulatory Update Table, August 1991

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M., Hawkins, G.T.; Salk, M.S.

    1991-09-01

    This Environmental Regulatory Update Table (August 1991) provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  1. Environmental regulatory update table, July 1991

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.

    1991-08-01

    This Environmental Regulatory Update Table (July 1991) provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated each month with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  2. Sugammadex: An Update

    Directory of Open Access Journals (Sweden)

    Ezri Tiberiu

    2016-01-01

    Full Text Available The purpose of this update is to provide recent knowledge and debates regarding the use of sugammadex in the fields of anesthesia and critical care. The review is not intended to provide a comprehensive description of sugammadex and its clinical use.

  3. Non-linear Bayesian update of PCE coefficients

    KAUST Repository

    Litvinenko, Alexander

    2014-01-06

    Given: a physical system modeled by a PDE or ODE with uncertain coefficient q(?), a measurement operator Y (u(q), q), where u(q, ?) uncertain solution. Aim: to identify q(?). The mapping from parameters to observations is usually not invertible, hence this inverse identification problem is generally ill-posed. To identify q(!) we derived non-linear Bayesian update from the variational problem associated with conditional expectation. To reduce cost of the Bayesian update we offer a unctional approximation, e.g. polynomial chaos expansion (PCE). New: We apply Bayesian update to the PCE coefficients of the random coefficient q(?) (not to the probability density function of q).

  4. Non-linear Bayesian update of PCE coefficients

    KAUST Repository

    Litvinenko, Alexander; Matthies, Hermann G.; Pojonk, Oliver; Rosic, Bojana V.; Zander, Elmar

    2014-01-01

    Given: a physical system modeled by a PDE or ODE with uncertain coefficient q(?), a measurement operator Y (u(q), q), where u(q, ?) uncertain solution. Aim: to identify q(?). The mapping from parameters to observations is usually not invertible, hence this inverse identification problem is generally ill-posed. To identify q(!) we derived non-linear Bayesian update from the variational problem associated with conditional expectation. To reduce cost of the Bayesian update we offer a unctional approximation, e.g. polynomial chaos expansion (PCE). New: We apply Bayesian update to the PCE coefficients of the random coefficient q(?) (not to the probability density function of q).

  5. The effects of foreknowledge and task-set shifting as mirrored in cue- and target-locked event-related potentials.

    Directory of Open Access Journals (Sweden)

    Mareike Finke

    Full Text Available The present study examined the use of foreknowledge in a task-cueing protocol while manipulating sensory updating and executive control in both, informatively and non-informatively pre-cued trials. Foreknowledge, sensory updating (cue switch effects and task-switching were orthogonally manipulated in order to address the question of whether, and to which extent, the sensory processing of cue changes can partly or totally explain the final task switch costs. Participants responded faster when they could prepare for the upcoming task and if no task-set updating was necessary. Sensory cue switches influenced cue-locked ERPs only when they contained conceptual information about the upcoming task: frontal P2 amplitudes were modulated by task-relevant cue changes, mid-parietal P3 amplitudes by the anticipatory updating of stimulus-response mappings, and P3 peak latencies were modulated by task switching. Task preparation was advantageous for efficient stimulus-response re-mapping at target-onset as mirrored in target N2 amplitudes. However, N2 peak latencies indicate that this process is faster for all repeat trials. The results provide evidence to support a very fast detection of task-relevance in sensory (cue changes and argue against the view of task repetition benefits as secondary to purely perceptual repetition priming. Advanced preparation may have a stronger influence on behavioral performance and target-locked brain activity than the local effect of repeating or switching the task-set in the current trial.

  6. Estructura y Funcionamiento del Proceso de Cálculo del Coste en los Servicios Hospitalarios: Una Experiencia Empírica.

    Directory of Open Access Journals (Sweden)

    Daniel Carrasco Díaz

    1997-12-01

    Full Text Available El objeto del trabajo se concreta en explicitar, sintéticamente, las cuestiones planteadas en la aplicación de un modelo de costes a un proceso productivo peculiar como es la actividad hospitalaria. Lo anterior se hace en base a la experiencia empírica de un estudio llevado a cabo en varios hospitales del Servicio Andaluz de Salud para determinar el coste de los centros de explotación del hospital y de sus productos o servicios sanitarios prestados. Una vez justificado el enfoque de asignación de costes más idóneo, se catalogan los factores y lugares específicos de dicha actividad, como instrumentos básicos en su aplicación. Finalmente, se ponen de relieve los problemas y soluciones adoptadas en el proceso de cálculo para cuantificar el computo de los diversos factores y el análisis que requiere la elección de las claves de reparto, tanto para su asignación entre todos los centros, como en la redistribución del coste absorbido por los auxiliares entre los principales para determinar su montante total, así como las dificultades que conlleva un análisis comparativo de los principales datos de la investigación empírica.The purpose of the study is to demonstrate, synthetically, the problems raised in the application of a costs model to a peculiar productive process as is hospital activity. The foregoing is based on the empirical experience of a study carried out in several hospitals of the "Servicio Andaluz de Salud" to determine the cost of the hospital development centres, and of its products or the health services it offers. Once the most suitable cost approach has been justified, the specific factors and places of side activity is catalogued as basic instruments in its application. Finally, we explain the problems and solutions adopted in the calculation to quantify the various factors, and the analysis required by the choice of the allotment criteria, both with respects to its allocation amog redistribution of the cost

  7. Identification of self-consistent modulons from bacterial microarray expression data with the help of structured regulon gene sets

    KAUST Repository

    Permina, Elizaveta A.; Medvedeva, Yulia; Baeck, Pia M.; Hegde, Shubhada R.; Mande, Shekhar C.; Makeev, Vsevolod J.

    2013-01-01

    interactions helps to evaluate parameters for regulatory subnetwork inference. We suggest a procedure for modulon construction where a seed regulon is iteratively updated with genes having expression patterns similar to those for regulon member genes. A set

  8. Control of Interference during Working Memory Updating

    Science.gov (United States)

    Szmalec, Arnaud; Verbruggen, Frederick; Vandierendonck, Andre; Kemps, Eva

    2011-01-01

    The current study examined the nature of the processes underlying working memory updating. In 4 experiments using the n-back paradigm, the authors demonstrate that continuous updating of items in working memory prevents strong binding of those items to their contexts in working memory, and hence leads to an increased susceptibility to proactive…

  9. 42 CFR 414.30 - Conversion factor update.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Conversion factor update. 414.30 Section 414.30... Practitioners § 414.30 Conversion factor update. Unless Congress acts in accordance with section 1848(d)(3) of... preceding FY over the third preceding FY exceeds the performance standard rate of increase established for...

  10. Application of Real Time Models Updating in ABO Central Field

    International Nuclear Information System (INIS)

    Heikal, S.; Adewale, D.; Doghmi, A.; Augustine, U.

    2003-01-01

    ABO central field is the first deep offshore oil production in Nigeria located in OML 125 (ex-OPL316). The field was developed in a water depth of between 500 and 800 meters. Deep-water development requires much faster data handling and model updates in order to make the best possible technical decision. This required an easy way to incorporate the latest information and dynamic update of the reservoir model enabling real time reservoir management. The paper aims at discussing the benefits of real time static and dynamic model update and illustrates with a horizontal well example how this update was beneficial prior and during the drilling operation minimizing the project CAPEX Prior to drilling, a 3D geological model was built based on seismic and offset wells' data. The geological model was updated twice, once after the pilot hole drilling and then after reaching the landing point and prior drilling the horizontal section .Forward modeling ws made was well using the along the planned trajectory. During the drilling process both geo- steering and LWD data were loaded in real time to the 3D modeling software. The data was analyzed and compared with the predicted model. The location of markers was changed as drilling progressed and the entire 3D Geological model was rapidly updated. The target zones were revaluated in the light of the new model updates. Recommendations were communicated to the field, and the well trajectory was modified to take into account the new information. The combination of speed, flexibility and update-ability of the 3D modeling software enabled continues geological model update on which the asset team based their trajectory modification decisions throughout the drilling phase. The well was geo-steered through 7 meters thickness of sand. After the drilling, the testing showed excellent results with a productivity and fluid properties data were used to update the dynamic model reviewing the well production plateau providing optimum reservoir

  11. Impacto de la innovación sobre el rendimiento de la mipyme: Un estudio empírico en Colombia

    Directory of Open Access Journals (Sweden)

    Edgar Julián Gálvez Albarracín, Ph.D

    2012-01-01

    Full Text Available El objetivo de este trabajo es verificar empíricamente la relación existente entre el grado de innovación de la empresa y su rendimiento, para lo cual se realiza un estudio con sesenta micro, pequeñas y medianas empresas (MIPYME de mediana y alta tecnología de la ciudad de Cali (Colombia. Los resultados muestran que la innovación en productos y en procesos ejerce una influencia positiva sobre el rendimiento de la MIPYME. Estos hallazgos refuerzan los postulados que muestran a la innovación como una ventaja competitiva sostenible, así mismo pueden ser de utilidad para los empresarios, al constatar la necesidad de innovar para mejorar su competitividad y para la administración pública en su papel de promotora de la innovación a través de programas de apoyo financiero y no financiero.

  12. Effect of asynchronous updating on the stability of cellular automata

    International Nuclear Information System (INIS)

    Baetens, J.M.; Van der Weeën, P.; De Baets, B.

    2012-01-01

    Highlights: ► An upper bound on the Lyapunov exponent of asynchronously updated CA is established. ► The employed update method has repercussions on the stability of CAs. ► A decision on the employed update method should be taken with care. ► Substantial discrepancies arise between synchronously and asynchronously updated CA. ► Discrepancies between different asynchronous update schemes are less pronounced. - Abstract: Although cellular automata (CAs) were conceptualized as utter discrete mathematical models in which the states of all their spatial entities are updated simultaneously at every consecutive time step, i.e. synchronously, various CA-based models that rely on so-called asynchronous update methods have been constructed in order to overcome the limitations that are tied up with the classical way of evolving CAs. So far, only a few researchers have addressed the consequences of this way of updating on the evolved spatio-temporal patterns, and the reachable stationary states. In this paper, we exploit Lyapunov exponents to determine to what extent the stability of the rules within a family of totalistic CAs is affected by the underlying update method. For that purpose, we derive an upper bound on the maximum Lyapunov exponent of asynchronously iterated CAs, and show its validity, after which we present a comparative study between the Lyapunov exponents obtained for five different update methods, namely one synchronous method and four well-established asynchronous methods. It is found that the stability of CAs is seriously affected if one of the latter methods is employed, whereas the discrepancies arising between the different asynchronous methods are far less pronounced and, finally, we discuss the repercussions of our findings on the development of CA-based models.

  13. Equivalência de estímulos e autismo: uma revisão de estudos empíricos

    Directory of Open Access Journals (Sweden)

    Camila Graciella Santos Gomes

    Full Text Available O modelo de equivalência de estímulos oferece uma especificação operacional do comportamento simbólico e tem orientado o ensino e a verificação objetiva de repertórios novos. Pessoas com autismo, caracterizadas por apresentarem, entre outras alterações, graves déficits de linguagem, poderiam se beneficiar de estratégias baseadas neste modelo. Este artigo apresenta uma revisão de publicações de estudos empíricos com autistas, fundamentados no paradigma de equivalência. Os resultados mostraram sucesso de alguns participantes e fracasso de outros. Os fracassos parecem residir mais em dificuldades em aprender relações arbitrárias e menos na emergência de relações novas após aquisição da linha de base. O desafio para a área é desenvolver procedimentos que favoreçam a aprendizagem de relações arbitrárias e, consequentemente, a formação de classes de estímulos equivalentes.

  14. A comparison of updating algorithms for large N reduced models

    Energy Technology Data Exchange (ETDEWEB)

    Pérez, Margarita García [Instituto de Física Teórica UAM-CSIC, Universidad Autónoma de Madrid,Nicolás Cabrera 13-15, E-28049-Madrid (Spain); González-Arroyo, Antonio [Instituto de Física Teórica UAM-CSIC, Universidad Autónoma de Madrid,Nicolás Cabrera 13-15, E-28049-Madrid (Spain); Departamento de Física Teórica, C-XI Universidad Autónoma de Madrid,E-28049 Madrid (Spain); Keegan, Liam [PH-TH, CERN,CH-1211 Geneva 23 (Switzerland); Okawa, Masanori [Graduate School of Science, Hiroshima University,Higashi-Hiroshima, Hiroshima 739-8526 (Japan); Core of Research for the Energetic Universe, Hiroshima University,Higashi-Hiroshima, Hiroshima 739-8526 (Japan); Ramos, Alberto [PH-TH, CERN,CH-1211 Geneva 23 (Switzerland)

    2015-06-29

    We investigate Monte Carlo updating algorithms for simulating SU(N) Yang-Mills fields on a single-site lattice, such as for the Twisted Eguchi-Kawai model (TEK). We show that performing only over-relaxation (OR) updates of the gauge links is a valid simulation algorithm for the Fabricius and Haan formulation of this model, and that this decorrelates observables faster than using heat-bath updates. We consider two different methods of implementing the OR update: either updating the whole SU(N) matrix at once, or iterating through SU(2) subgroups of the SU(N) matrix, we find the same critical exponent in both cases, and only a slight difference between the two.

  15. A comparison of updating algorithms for large $N$ reduced models

    CERN Document Server

    Pérez, Margarita García; Keegan, Liam; Okawa, Masanori; Ramos, Alberto

    2015-01-01

    We investigate Monte Carlo updating algorithms for simulating $SU(N)$ Yang-Mills fields on a single-site lattice, such as for the Twisted Eguchi-Kawai model (TEK). We show that performing only over-relaxation (OR) updates of the gauge links is a valid simulation algorithm for the Fabricius and Haan formulation of this model, and that this decorrelates observables faster than using heat-bath updates. We consider two different methods of implementing the OR update: either updating the whole $SU(N)$ matrix at once, or iterating through $SU(2)$ subgroups of the $SU(N)$ matrix, we find the same critical exponent in both cases, and only a slight difference between the two.

  16. El carácter empírico y lógico de la contabilidad

    Directory of Open Access Journals (Sweden)

    Eduardo R. Scarano

    2009-12-01

    Full Text Available El objetivo de este artículo es argumentar acerca del carácter esencialmente empírico y científico de la contabilidad. Este punto de vista implica rechazar el carácter predominantemente normativo que posee la contabilidad, por lo menos, en Latinoamérica. Se considera que el normativismo de cualquier tipo es meramente secundario.La contabilidad es una disciplina científica, pero al carecer de leyes estrictas no constituye una ciencia básica, es una tecnología social.Se mostrará que tiene una estructura axiomática específica que se puede exponer con la lógica estándar, lo mismo que la matemática contable que supone la partida doble.The aim of this article is to argue about the essentially empirical and scientific character of the accounting. This point of view implies rejecting the predominantly normative character that possesses the accounting, at least, in Latin America. It thinks that the normativism of any type is merely secondary.The accounting is a scientific discipline, but it lacks strict laws, therefore, it does not constitute a basic science, is a social technology.It will appear that it has an axiomatic specific structure that can be exposed by the standard logic the same as the accounting mathematics that supposes the double entry.

  17. Inadimplência no Brasil: Uma Análise das Evidências Empíricas

    Directory of Open Access Journals (Sweden)

    Mariane Daros

    2017-08-01

    Full Text Available O objetivo deste trabalho consiste em analisar as evidências empíricas de estudos relacionados à inadimplência dentro do contexto brasileiro, verificando os estudos desses aspectos nas diversas regiões do país. Além disso, foram analisadas questões relacionadas ao panorama desses estudos a fim de verificar em quais pontos os trabalhos futuros desse tema podem vir a avançar. A partir da análise dos estudos publicados dentro da temática nota-se a existência de alguns pontos que não são aprofundados e que podem avançar por meio de estudos futuros. Dentre esses pontos estão: exploração do tema em todos os setores da economia, maior variação na utilização de procedimentos metodológicos, utilização de série temporal para verificar a evolução do fenômeno e associar a inadimplência com outras temáticas correlatas a essa questão como o endividamento, alfabetização financeira, consumismo, motivações pessoais do indivíduo, aspectos socioeconômicos e causas que podem ter ligação no produto e serviço disponibilizado ao consumidor.

  18. Update neutron nuclear data evaluation for 236,238Np

    International Nuclear Information System (INIS)

    Chen, Guochang; Wang, Jimin; Yu, Baosheng; Cao, Wentian; Tang, Guo-you

    2015-01-01

    The nuclear data with high accuracy for actinides play an important role in nuclear technology applications, including reactor design and operation, fuel cycle, estimation of the amount of minor actinides (MAs) in high burnup reactors and to research to transmute the MAs to short half-lived nuclides or stable ones. The nuclides of 236 Np are generated via the α-decay of 240 Am or 237 Np(n, 2n) and 237 Np(d, t) reactions. And the nuclides of 238 Np are generated via the α-decay of 242 Am or 237 Np(n, γ) and 237 Np(d, p) reactions. In the present work, according to the systematic trend of the total cross section and elastic cross section etc. of different Np isotopes, and based on the neutron optical model parameters (OMP) of 237 Np, a new set of neutron optical model parameters were obtained for 236,238 Np. Based on the new set OMP and the systematic trend of the cross sections of different Np isotopes, a full set of 236,238 Np neutron nuclear data has been updated and improved by theoretical calculation. The present result has significant improvements over the data in CENDL-3.1

  19. Energy Economic Data Base (EEDB) Program: Phase VI update (1983) report

    International Nuclear Information System (INIS)

    1984-09-01

    This update of the Energy Economic Data Base is the latest in a series of technical and cost studies prepared by United Engineers and Constructors Inc., during the last 18 years. The data base was developed during 1978 and has been updated annually since then. The purpose of the updates has been to reflect the impact of changing regulations and technology on the costs of electric power generating stations. This Phase VI (Sixth) Update report documents the results of the 1983 EEDB Program update effort. The latest effort was a comprehensive update of the technical and capital cost information for the pressurized water reactor, boiling water reactor, and liquid metal fast breeder reactor nuclear power plant data models and for the 800 MWe and 500 MWe high sulfur coal-fired power plant data models. The update provided representative costs for these nuclear and coal-fired power plants for the 1980's. In addition, the updated nuclear power plant data models for the 1980's were modified to provide anticipated costs for nuclear power plants for the 1990's. Consequently, the Phase VI Update has continued to provide important benchmark information through which technical and capital cost trends may be identified that have occurred since January 1, 1978

  20. Indoor Spatial Updating with Reduced Visual Information.

    Science.gov (United States)

    Legge, Gordon E; Gage, Rachel; Baek, Yihwa; Bochsler, Tiana M

    2016-01-01

    Spatial updating refers to the ability to keep track of position and orientation while moving through an environment. People with impaired vision may be less accurate in spatial updating with adverse consequences for indoor navigation. In this study, we asked how artificial restrictions on visual acuity and field size affect spatial updating, and also judgments of the size of rooms. Normally sighted young adults were tested with artificial restriction of acuity in Mild Blur (Snellen 20/135) and Severe Blur (Snellen 20/900) conditions, and a Narrow Field (8°) condition. The subjects estimated the dimensions of seven rectangular rooms with and without these visual restrictions. They were also guided along three-segment paths in the rooms. At the end of each path, they were asked to estimate the distance and direction to the starting location. In Experiment 1, the subjects walked along the path. In Experiment 2, they were pushed in a wheelchair to determine if reduced proprioceptive input would result in poorer spatial updating. With unrestricted vision, mean Weber fractions for room-size estimates were near 20%. Severe Blur but not Mild Blur yielded larger errors in room-size judgments. The Narrow Field was associated with increased error, but less than with Severe Blur. There was no effect of visual restriction on estimates of distance back to the starting location, and only Severe Blur yielded larger errors in the direction estimates. Contrary to expectation, the wheelchair subjects did not exhibit poorer updating performance than the walking subjects, nor did they show greater dependence on visual condition. If our results generalize to people with low vision, severe deficits in acuity or field will adversely affect the ability to judge the size of indoor spaces, but updating of position and orientation may be less affected by visual impairment.

  1. Indoor Spatial Updating with Reduced Visual Information.

    Directory of Open Access Journals (Sweden)

    Gordon E Legge

    Full Text Available Spatial updating refers to the ability to keep track of position and orientation while moving through an environment. People with impaired vision may be less accurate in spatial updating with adverse consequences for indoor navigation. In this study, we asked how artificial restrictions on visual acuity and field size affect spatial updating, and also judgments of the size of rooms.Normally sighted young adults were tested with artificial restriction of acuity in Mild Blur (Snellen 20/135 and Severe Blur (Snellen 20/900 conditions, and a Narrow Field (8° condition. The subjects estimated the dimensions of seven rectangular rooms with and without these visual restrictions. They were also guided along three-segment paths in the rooms. At the end of each path, they were asked to estimate the distance and direction to the starting location. In Experiment 1, the subjects walked along the path. In Experiment 2, they were pushed in a wheelchair to determine if reduced proprioceptive input would result in poorer spatial updating.With unrestricted vision, mean Weber fractions for room-size estimates were near 20%. Severe Blur but not Mild Blur yielded larger errors in room-size judgments. The Narrow Field was associated with increased error, but less than with Severe Blur. There was no effect of visual restriction on estimates of distance back to the starting location, and only Severe Blur yielded larger errors in the direction estimates. Contrary to expectation, the wheelchair subjects did not exhibit poorer updating performance than the walking subjects, nor did they show greater dependence on visual condition.If our results generalize to people with low vision, severe deficits in acuity or field will adversely affect the ability to judge the size of indoor spaces, but updating of position and orientation may be less affected by visual impairment.

  2. Optimal timing for intravascular administration set replacement.

    Science.gov (United States)

    Ullman, Amanda J; Cooke, Marie L; Gillies, Donna; Marsh, Nicole M; Daud, Azlina; McGrail, Matthew R; O'Riordan, Elizabeth; Rickard, Claire M

    2013-09-15

    The tubing (administration set) attached to both venous and arterial catheters may contribute to bacteraemia and other infections. The rate of infection may be increased or decreased by routine replacement of administration sets. This review was originally published in 2005 and was updated in 2012. The objective of this review was to identify any relationship between the frequency with which administration sets are replaced and rates of microbial colonization, infection and death. We searched The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2012, Issue 6), MEDLINE (1950 to June 2012), CINAHL (1982 to June 2012), EMBASE (1980 to June 2012), reference lists of identified trials and bibliographies of published reviews. The original search was performed in February 2004. We also contacted researchers in the field. We applied no language restriction. We included all randomized or controlled clinical trials on the frequency of venous or arterial catheter administration set replacement in hospitalized participants. Two review authors assessed all potentially relevant studies. We resolved disagreements between the two review authors by discussion with a third review author. We collected data for seven outcomes: catheter-related infection; infusate-related infection; infusate microbial colonization; catheter microbial colonization; all-cause bloodstream infection; mortality; and cost. We pooled results from studies that compared different frequencies of administration set replacement, for instance, we pooled studies that compared replacement ≥ every 96 hours versus every 72 hours with studies that compared replacement ≥ every 48 hours versus every 24 hours. We identified 26 studies for this updated review, 10 of which we excluded; six did not fulfil the inclusion criteria and four did not report usable data. We extracted data from the remaining 18 references (16 studies) with 5001 participants: study designs included neonate and adult

  3. Do lateral boundary condition update frequency and the resolution of the boundary data affect the regional model COSMO-CLM? A sensitivity study.

    Science.gov (United States)

    Pankatz, K.; Kerkweg, A.

    2014-12-01

    The work presented is part of the joint project "DecReg" ("Regional decadal predictability") which is in turn part of the project "MiKlip" ("Decadal predictions"), an effort funded by the german Federal Ministry of Education and Research to improve decadal predictions on a global and regional scale. In regional climate modeling it is common to update the lateral boundary conditions (LBC) of the regional model every six hours. This is mainly due to the fact, that reference data sets like ERA are only available every six hours. Additionally, for offline coupling procedures it would be too costly to store LBC data in higher temporal resolution for climate simulations. However, theoretically, the coupling frequency could be as high as the time step of the driving model. Meanwhile, it is unclear if a more frequent update of the LBC has a significant effect on the climate in the domain of the regional model (RCM). This study uses the RCM COSMO-CLM/MESSy (Kerkweg and Jöckel, 2012) to couple COSMO-CLM offline to the GCM ECHAM5. One study examines a 30 year time slice experiment for three update frequencies of the LBC, namely six hours, one hour and six minutes. The evaluation of means, standard deviations and statistics of the climate in regional domain shows only small deviations, some stastically significant though, of 2m temperature, sea level pressure and precipitaion.The second scope of the study assesses parameters linked to cyclone activity, which is affected by the LBC update frequency. Differences in track density and strength are found when comparing the simulations.The second study examines the quality of decadal hind-casts of the decade 2001-2010 when the horizontal resolution of the driving model, namely T42, T63, T85, T106, from which the LBC are calculated, is altered. Two sets of simulations are evaluated. For the first set of simulations, the GCM simulations are performed at different resolutions using the same boundary conditions for GHGs and SSTs, thus

  4. Impact of the updating scheme on stationary states of networks

    International Nuclear Information System (INIS)

    Radicchi, F; Ahn, Y Y; Meyer-Ortmanns, H

    2008-01-01

    From Boolean networks it is well known that the number of attractors as a function of the system size depends on the updating scheme which is chosen either synchronously or asynchronously. In this contribution, we report on a systematic interpolation between synchronous and asynchronous updating in a one-dimensional chain of Ising spins. The stationary state for fully synchronous updating is antiferromagnetic. The interpolation allows us to locate a phase transition between phases with an absorbing and a fluctuating stationary state. The associated universality class is that of parity conservation. We also report on a more recent study of asynchronous updates applied to the yeast cell-cycle network. Compared to the synchronous update, the basin of attraction of the largest attractor considerably shrinks and the convergence to the biological pathway slows down and is less dominant. Both examples illustrate how sensitively the stationary states and the properties of attractors can depend on the updating mode of the algorithm

  5. Land Boundary Conditions for the Goddard Earth Observing System Model Version 5 (GEOS-5) Climate Modeling System: Recent Updates and Data File Descriptions

    Science.gov (United States)

    Mahanama, Sarith P.; Koster, Randal D.; Walker, Gregory K.; Takacs, Lawrence L.; Reichle, Rolf H.; De Lannoy, Gabrielle; Liu, Qing; Zhao, Bin; Suarez, Max J.

    2015-01-01

    The Earths land surface boundary conditions in the Goddard Earth Observing System version 5 (GEOS-5) modeling system were updated using recent high spatial and temporal resolution global data products. The updates include: (i) construction of a global 10-arcsec land-ocean lakes-ice mask; (ii) incorporation of a 10-arcsec Globcover 2009 land cover dataset; (iii) implementation of Level 12 Pfafstetter hydrologic catchments; (iv) use of hybridized SRTM global topography data; (v) construction of the HWSDv1.21-STATSGO2 merged global 30 arc second soil mineral and carbon data in conjunction with a highly-refined soil classification system; (vi) production of diffuse visible and near-infrared 8-day MODIS albedo climatologies at 30-arcsec from the period 2001-2011; and (vii) production of the GEOLAND2 and MODIS merged 8-day LAI climatology at 30-arcsec for GEOS-5. The global data sets were preprocessed and used to construct global raster data files for the software (mkCatchParam) that computes parameters on catchment-tiles for various atmospheric grids. The updates also include a few bug fixes in mkCatchParam, as well as changes (improvements in algorithms, etc.) to mkCatchParam that allow it to produce tile-space parameters efficiently for high resolution AGCM grids. The update process also includes the construction of data files describing the vegetation type fractions, soil background albedo, nitrogen deposition and mean annual 2m air temperature to be used with the future Catchment CN model and the global stream channel network to be used with the future global runoff routing model. This report provides detailed descriptions of the data production process and data file format of each updated data set.

  6. The Geysers-Clear Lake geothermal area, California - an updated geophysical perspective of heat sources

    Science.gov (United States)

    Stanley, W.D.; Blakely, R.J.

    1995-01-01

    The Geysers-Clear Lake geothermal area encompasses a large dry-steam production area in The Geysers field and a documented high-temperature, high-pressure, water-dominated system in the area largely south of Clear Lake, which has not been developed. An updated view is presented of the geological/geophysical complexities of the crust in this region in order to address key unanswered questions about the heat source and tectonics. Forward modeling, multidimensional inversions, and ideal body analysis of the gravity data, new electromagnetic sounding models, and arguments made from other geophysical data sets suggest that many of the geophysical anomalies have significant contributions from rock property and physical state variations in the upper 7 km and not from "magma' at greater depths. Regional tectonic and magmatic processes are analyzed to develop an updated scenario for pluton emplacement that differs substantially from earlier interpretations. In addition, a rationale is outlined for future exploration for geothermal resources in The Geysers-Clear Lake area. -from Authors

  7. Lessons Learned in the Update of a Safety Limit for the High Flux Isotope Reactor

    International Nuclear Information System (INIS)

    Cook, David Howard

    2009-01-01

    A recent unreviewed safety question (USQ) regarding a portion of the High Flux Isotope Reactor (HFIR) transient decay heat removal analysis focused on applicability of a heat transfer correlation at the low flow end of reactor operations. During resolution of this issue, review of the correlations used to establish the safety limit (SL) on reactor flux-to-flow ratio revealed the need to change the magnitude of the SL at the low flow end of reactor operations and the need to update the hot spot fuel damage criteria to incorporate current knowledge involving parallel channel flow stability. Because of the original safety design strategy for the reactor, resolution of the issues for the flux-to-flow ratio involved reevaluation of all key process variable SLs and limiting control settings (LCSs) using the current version of the heat transfer analysis code for the reactor. Goals of the work involved updating and upgrading the SL analysis where necessary, while preserving the safety design strategy for the reactor. Changes made include revisions to the safety design criteria at low flows to address the USQ, update of the process- and analysis input-variable uncertainty considerations, and upgrade of the safety design criteria at high flow. The challenges faced during update/upgrade of this SL and LCS are typical of the problems found in the integration of safety into the design process for a complex facility. In particular, the problems addressed in the area of instrument uncertainties provide valuable lessons learned for establishment and configuration control of SLs for large facilities

  8. Key Techniques for Dynamic Updating of National Fundamental Geographic Information Database

    Directory of Open Access Journals (Sweden)

    WANG Donghua

    2015-07-01

    Full Text Available One of the most important missions of fundamental surveying and mapping work is to keep the fundamental geographic information fresh. In this respect, National Administration of Surveying, Mapping and Geoinformation has launched the project of dynamic updating of national fundamental geographic information database since 2012, which aims to update 1:50 000, 1:250 000 and 1:1 000 000 national fundamental geographic information database continuously and quickly, by updating and publishing once a year. This paper introduces the general technical thinking of dynamic updating, states main technical methods, such as dynamic updating of fundamental database, linkage updating of derived databases, and multi-tense database management and service and so on, and finally introduces main technical characteristics and engineering applications.

  9. Eastern Hemisphere set for 1991

    International Nuclear Information System (INIS)

    Anon.

    1990-01-01

    Give yourself an edge by acquiring quick access to over 40,000 names and titles of key operating personnel in the industry throughout more than 100 countries in a part of the world which is crucial to international petroleum activity. Both the European Petroleum Directory and the Asia-Pacific/Africa-Middle East Petroleum Directory provide complete names, addresses, personnel, phone numbers, fax numbers, telex numbers, and cable numbers for companies involved in drilling, refining, exploration, pipelines, engineering, field services, construction and many other petroleum-related operations. This book is a source of information for updating mailing lists and prospect files and for shopping for competitive bids on equipment and services. Also provided is the Oil ampersand Gas Journal's Worldwide Production Survey for all the countries included in the set

  10. Choosing Important Health Outcomes for Comparative Effectiveness Research: An Updated Review and Identification of Gaps.

    Science.gov (United States)

    Gorst, Sarah L; Gargon, Elizabeth; Clarke, Mike; Smith, Valerie; Williamson, Paula R

    2016-01-01

    The COMET (Core Outcome Measures in Effectiveness Trials) Initiative promotes the development and application of core outcome sets (COS), including relevant studies in an online database. In order to keep the database current, an annual search of the literature is undertaken. This study aimed to update a previous systematic review, in order to identify any further studies where a COS has been developed. Furthermore, no prioritization for COS development has previously been undertaken, therefore this study also aimed to identify COS relevant to the world's most prevalent health conditions. The methods used in this updated review followed the same approach used in the original review and the previous update. A survey was also sent to the corresponding authors of COS identified for inclusion in this review, to ascertain what lessons they had learnt from developing their COS. Additionally, the COMET database was searched to identify COS that might be relevant to the conditions with the highest global prevalence. Twenty-five reports relating to 22 new studies were eligible for inclusion in the review. Further improvements were identified in relation to the description of the scope of the COS, use of the Delphi technique, and the inclusion of patient participants within the development process. Additionally, 33 published and ongoing COS were identified for 13 of the world's most prevalent conditions. The development of a reporting guideline and minimum standards should contribute towards future improvements in development and reporting of COS. This study has also described a first approach to identifying gaps in existing COS, and to priority setting in this area. Important gaps have been identified, on the basis of global burden of disease, and the development and application of COS in these areas should be considered a priority.

  11. Updating the definition and role of public health nursing to advance and guide the specialty.

    Science.gov (United States)

    Bekemeier, Betty; Walker Linderman, Tessa; Kneipp, Shawn; Zahner, Susan J

    2015-01-01

    National changes in the context for public health services are influencing the nature of public health nursing practice. Despite this, the document that defines public health nursing as a specialty--The Definition and Role of Public Health Nursing--has remained in wide use since its publication in 1996 without a review or update. With support from the American Public Health Association (APHA) Public Health Nursing Section, a national Task Force, was formed in November 2012 to update the definition of public health nursing, using processes that reflected deliberative democratic principles. A yearlong process was employed that included a modified Delphi technique and various modes of engagement such as online discussion boards, questionnaires, and public comment to review. The resulting 2013 document consisted of a reaffirmation of the one-sentence 1996 definition, while updating supporting documentation to align with the current social, economic, political, and health care context. The 2013 document was strongly endorsed by vote of the APHA Public Health Nursing Section elected leadership. The 2013 definition and document affirm the relevance of a population-focused definition of public health nursing to complex systems addressed in current practice and articulate critical roles of public health nurses (PHN) in these settings. © 2014 Wiley Periodicals, Inc.

  12. Statistical and perceptual updating: correlated impairments in right brain injury.

    Science.gov (United States)

    Stöttinger, Elisabeth; Filipowicz, Alex; Marandi, Elahe; Quehl, Nadine; Danckert, James; Anderson, Britt

    2014-06-01

    It has been hypothesized that many of the cognitive impairments commonly seen after right brain damage (RBD) can be characterized as a failure to build or update mental models. We (Danckert et al. in Neglect as a disorder of representational updating. NOVA Open Access, New York, 2012a; Cereb Cortex 22:2745-2760, 2012b) were the first to directly assess the association between RBD and updating and found that RBD patients were unable to exploit a strongly biased play strategy in their opponent in the children's game rock, paper, scissors. Given that this game required many other cognitive capacities (i.e., working memory, sustained attention, reward processing), RBD patients could have failed this task for various reasons other than a failure to update. To assess the generality of updating deficits after RBD, we had RBD, left brain-damaged (LBD) patients and healthy controls (HCs) describe line drawings that evolved gradually from one figure (e.g., rabbit) to another (e.g., duck) in addition to the RPS updating task. RBD patients took significantly longer to alter their perceptual report from the initial object to the final object than did LBD patients and HCs. Although both patient groups performed poorly on the RPS task, only the RBD patients showed a significant correlation between the two, very different, updating tasks. We suggest these data indicate a general deficiency in the ability to update mental representations following RBD.

  13. Supporting Frequent Updates in R-Trees: A Bottom-Up Approach

    DEFF Research Database (Denmark)

    Lee, Mong Li; Hsu, Wynne; Jensen, Christian Søndergaard

    2003-01-01

    Advances in hardware-related technologies promise to enable new data management applications that monitor continuous processes. In these applications, enormous amounts of state samples are obtained via sensors and are streamed to a database. Further, updates are very frequent and may exhibit...... and aims to improve update performance. It has different levels of reorganization—ranging from global to local—during updates, avoiding expensive top-down updates. A compact main-memory summary structure that allows direct access to the R-tree index nodes is used together with efficient bottom...

  14. The distance effect in numerical memory-updating tasks.

    Science.gov (United States)

    Lendínez, Cristina; Pelegrina, Santiago; Lechuga, Teresa

    2011-05-01

    Two experiments examined the role of numerical distance in updating numerical information in working memory. In the first experiment, participants had to memorize a new number only when it was smaller than a previously memorized number. In the second experiment, updating was based on an external signal, which removed the need to perform any numerical comparison. In both experiments, distance between the memorized number and the new one was manipulated. The results showed that smaller distances between the new and the old information led to shorter updating times. This graded facilitation suggests that the process by which information is substituted in the focus of attention involves maintaining the shared features between the new and the old number activated and selecting other new features to be activated. Thus, the updating cost may be related to amount of new features to be activated in the focus of attention.

  15. Environmental Regulatory Update Table, January/February 1995

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Bock, R.E.; Mayer, S.J.; Salk, M.S.

    1995-03-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives impacting environmental, health, and safety management responsibilities. the table is updated bi-monthly with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  16. Environmental Regulatory Update Table, January/February 1995

    International Nuclear Information System (INIS)

    Houlberg, L.M.; Hawkins, G.T.; Bock, R.E.; Mayer, S.J.; Salk, M.S.

    1995-03-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives impacting environmental, health, and safety management responsibilities. the table is updated bi-monthly with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action

  17. Análisis empírico de la aplicación del modelo de modernización de la gestión para organizaciones en PyMEs colombianas

    Directory of Open Access Journals (Sweden)

    Rafael Pérez Uribe

    2013-08-01

    Full Text Available Esta publicación presenta tres grandes resultados de la aplicación del Modelo de Modernización para la Gestión de Organizaciones – MMGO- en 127 PyMEs colombianas: el análisis estadístico y psicométrico de los instrumentos utilizados en el MMGO, la evidencia empírica de la aplicación del Modelo en las 127 empresas y las recomendaciones para desarrollar una gestión empresarial de excelencia para la PyME colombiana.

  18. UCI2001: The updated catalogue of Italy

    International Nuclear Information System (INIS)

    Peresan, A.; Panza, G.F.

    2002-05-01

    A new updated earthquake catalogue for the Italian territory, named UCI2001, is described here; it consists of an updated and revised version of the CCI1996 catalogue (Peresan et al., 1997). The revision essentially corresponds to the incorporation of data from the NEIC (National Earthquake Information Centre) and ALPOR (Catalogo delle Alpi Orientali) catalogues, while the updating is performed using the NEIC Preliminary Determinations of Epicenters since 1986. A brief overview of the catalogues used for the monitoring of seismicity in the Italian area is provided, together with the essential information about the structure of the UCI2001 catalogue and a description of its format. A complete list of the events, as on May 1 2002, is given in the Appendix. (author)

  19. An updated global grid point surface air temperature anomaly data set: 1851--1990

    Energy Technology Data Exchange (ETDEWEB)

    Sepanski, R.J.; Boden, T.A.; Daniels, R.C.

    1991-10-01

    This document presents land-based monthly surface air temperature anomalies (departures from a 1951--1970 reference period mean) on a 5{degree} latitude by 10{degree} longitude global grid. Monthly surface air temperature anomalies (departures from a 1957--1975 reference period mean) for the Antarctic (grid points from 65{degree}S to 85{degree}S) are presented in a similar way as a separate data set. The data were derived primarily from the World Weather Records and the archives of the United Kingdom Meteorological Office. This long-term record of temperature anomalies may be used in studies addressing possible greenhouse-gas-induced climate changes. To date, the data have been employed in generating regional, hemispheric, and global time series for determining whether recent (i.e., post-1900) warming trends have taken place. This document also presents the monthly mean temperature records for the individual stations that were used to generate the set of gridded anomalies. The periods of record vary by station. Northern Hemisphere station data have been corrected for inhomogeneities, while Southern Hemisphere data are presented in uncorrected form. 14 refs., 11 figs., 10 tabs.

  20. 2014 Update of the United States National Seismic Hazard Maps

    Science.gov (United States)

    Petersen, M.D.; Mueller, C.S.; Haller, K.M.; Moschetti, M.; Harmsen, S.C.; Field, E.H.; Rukstales, K.S.; Zeng, Y.; Perkins, D.M.; Powers, P.; Rezaeian, S.; Luco, N.; Olsen, A.; Williams, R.

    2012-01-01

    The U.S. National Seismic Hazard Maps are revised every six years, corresponding with the update cycle of the International Building Code. These maps cover the conterminous U.S. and will be updated in 2014 using the best-available science that is obtained from colleagues at regional and topical workshops, which are convened in 2012-2013. Maps for Alaska and Hawaii will be updated shortly following this update. Alternative seismic hazard models discussed at the workshops will be implemented in a logic tree framework and will be used to develop the seismic hazard maps and associated products. In this paper we describe the plan to update the hazard maps, the issues raised in workshops up to March 2012, and topics that will be discussed at future workshops. An advisory panel will guide the development of the hazard maps and ensure that the maps are acceptable to a broad segment of the science and engineering communities. These updated maps will then be considered by end-users for inclusion in building codes, risk models, and public policy documents.

  1. Updating the biomedical engineering curriculum: Inclusion of Health Technology Assessment subjects.

    Science.gov (United States)

    Martinez Licona, Fabiola; Urbina, Edmundo Gerardo; Azpiroz-Leehan, Joaquin

    2010-01-01

    This paper describes the work being carried out at Metropolitan Autonomous University (UAM) in Mexico City with regard to the continuous evaluation and updating of the Biomedical Engineering (BME) curriculum. In particular the courses regarded as part of the BME basic branch are reduced and new sets of elective subjects are proposed in order to bring closer the research work at UAM with the subjects in the BME curriculum. Special emphasis is placed on subjects dealing with Health Technology Assessment (HTA) and Health economics, as this branch of the BME discipline is quite promising in Mexico, but there are very few professionals in the field with adequate qualifications.

  2. Efectividad del aprendizaje cooperativo en contabilidad: una contrastación empírica

    Directory of Open Access Journals (Sweden)

    María del Mar Delgado Hurtado

    2015-07-01

    Full Text Available La presente investigación tiene como objetivo verificar uno de los principales beneficios atribuidos a la metodología docente «aprendizaje cooperativo»: la obtención de mejores resultados de aprendizaje. Para ello hemos realizado un cuasiexperimento con la finalidad de comparar las calificaciones de un grupo de alumnos, en cuyo proceso de aprendizaje se ha empleado el aprendizaje cooperativo junto con la clase magistral, con las calificaciones de otro grupo, donde solo ha sido utilizada la clase magistral. Los resultados obtenidos tras la aplicación de un análisis de covarianza (ANCOVA, controlando el género, edad, las calificaciones previas del alumno, asistencia a clase, dedicación y motivación, revelan mejores resultados en el grupo de aprendizaje cooperativo que en el grupo de clase magistral. Adicionalmente comprobamos la efectividad de la metodología del aprendizaje cooperativo en diferentes niveles de aprendizaje, de acuerdo con la taxonomía de Bloom (1956. Los resultados reflejan diferencias significativas en el nivel de aplicación-análisis pero no en el nivel conocimiento-comprensión. Este trabajo contribuye a la literatura empírica sobre aprendizaje cooperativo, proporcionando evidencia adicional sobre la obtención de mejores resultados de aprendizaje en contabilidad, tras haber controlado el efecto de variables que previamente no habían sido consideradas en la contrastación de esta metodología como la dedicación del alumno y la motivación.

  3. Contraste empírico de la transferencia de tecnología en tres empresas de agricultura protegida en México

    Directory of Open Access Journals (Sweden)

    Carlos Gabriel Borbón Morales

    2015-01-01

    Full Text Available De acuerdo a algunos modelos teóricos de la transferencia de tecnología las empresas aprenden de otras empresas; en otras ocasiones las tecnologías se transfieren a partir de una política dirigida por el Gobierno donde las firmas, los centros de investigación y las instituciones de educación superior confluyen trasladando el conocimiento de un actor a otro; otro más, advierte la participación activa de la sociedad civil, que derivado de sus necesidades se transforma en el eje que articula el tránsito del conocimiento hacia su aplicación. En este trabajo se realiza un análisis de dichos modelos, con el fin de contrastarlos empíricamente utilizando casos de empresas que incorporan tecnología para la producción de hortalizas en invernaderos, caracterizando a sus actores, relacionando estas características y evaluando y las formas en las cuales estas empresas han vivido sus procesos de contacto, adaptación y modificación de la tecnología. Palabras clave: transferencia de tecnología, agricultura protegidaDe acuerdo a algunos modelos teóricos de la transferencia de tecnología las empresas aprenden de otras empresas; en otras ocasiones las tecnologías se transfieren a partir de una política dirigida por el Gobierno donde las firmas, los centros de investigación y las instituciones de educación superior confluyen trasladando el conocimiento de un actor a otro; otro más, advierte la participación activa de la sociedad civil, que derivado de sus necesidades se transforma en el eje que articula el tránsito del conocimiento hacia su aplicación. En este trabajo se realiza un análisis de dichos modelos, con el fin de contrastarlos empíricamente utilizando casos de empresas que incorporan tecnología para la producción de hortalizas en invernaderos, caracterizando a sus actores, relacionando estas características y evaluando y las formas en las cuales estas empresas han vivido sus procesos de contacto, adaptación y modificaci

  4. 78 FR 26244 - Updating of Employer Identification Numbers

    Science.gov (United States)

    2013-05-06

    ... Number, or EIN. Employers are required to know the identity of their responsible party. The amount of...-BK02 Updating of Employer Identification Numbers AGENCY: Internal Revenue Service (IRS), Treasury... assigned an employer identification number (EIN) to provide updated information to the IRS in the manner...

  5. 76 FR 28194 - Proposed FOIA Fee Schedule Update

    Science.gov (United States)

    2011-05-16

    ... DEFENSE NUCLEAR FACILITIES SAFETY BOARD 10 CFR Part 1703 Proposed FOIA Fee Schedule Update AGENCY... publishing its proposed Freedom of Information Act (FOIA) Fee Schedule Update and solicits comments from... on the proposed fee schedule should be mailed or delivered to the Office of the General Counsel...

  6. 75 FR 27228 - Proposed FOIA Fee Schedule Update

    Science.gov (United States)

    2010-05-14

    ... DEFENSE NUCLEAR FACILITIES SAFETY BOARD 10 CFR Part 1703 Proposed FOIA Fee Schedule Update AGENCY... publishing its proposed Freedom of Information Act (FOIA) Fee Schedule Update and solicits comments from... on the proposed fee schedule should be mailed or delivered to the Office of the General Counsel...

  7. Exploring cluster Monte Carlo updates with Boltzmann machines.

    Science.gov (United States)

    Wang, Lei

    2017-11-01

    Boltzmann machines are physics informed generative models with broad applications in machine learning. They model the probability distribution of an input data set with latent variables and generate new samples accordingly. Applying the Boltzmann machines back to physics, they are ideal recommender systems to accelerate the Monte Carlo simulation of physical systems due to their flexibility and effectiveness. More intriguingly, we show that the generative sampling of the Boltzmann machines can even give different cluster Monte Carlo algorithms. The latent representation of the Boltzmann machines can be designed to mediate complex interactions and identify clusters of the physical system. We demonstrate these findings with concrete examples of the classical Ising model with and without four-spin plaquette interactions. In the future, automatic searches in the algorithm space parametrized by Boltzmann machines may discover more innovative Monte Carlo updates.

  8. Exploring cluster Monte Carlo updates with Boltzmann machines

    Science.gov (United States)

    Wang, Lei

    2017-11-01

    Boltzmann machines are physics informed generative models with broad applications in machine learning. They model the probability distribution of an input data set with latent variables and generate new samples accordingly. Applying the Boltzmann machines back to physics, they are ideal recommender systems to accelerate the Monte Carlo simulation of physical systems due to their flexibility and effectiveness. More intriguingly, we show that the generative sampling of the Boltzmann machines can even give different cluster Monte Carlo algorithms. The latent representation of the Boltzmann machines can be designed to mediate complex interactions and identify clusters of the physical system. We demonstrate these findings with concrete examples of the classical Ising model with and without four-spin plaquette interactions. In the future, automatic searches in the algorithm space parametrized by Boltzmann machines may discover more innovative Monte Carlo updates.

  9. WIMS Library updating

    Energy Technology Data Exchange (ETDEWEB)

    Ravnik, M; Trkov, A [Inst. Jozef Stefan, Ljubljana (Slovenia); Holubar, A [Ustav Jaderneho Vyzkumu CSKAE, Rez (Serbia and Montenegro)

    1992-07-01

    At the end of 1990 the WIMS Library Update Project (WLUP) has been initiated at the International Atomic Energy Agency. The project was organized as an international research project, coordinated at the J. Stefan Institute. Up to now, 22 laboratories from 19 countries joined the project. Phase 1 of the project, which included WIMS input optimization for five experimental benchmark lattices, has been completed. The work presented in this paper describes also the results of Phase 2 of the Project, in which the cross sections based on ENDF/B-IV evaluated nuclear data library have been processed. (author) [Slovenian] Konec 1990 se je na Mednarodni agenciji za atomsko energijo zacel projekt obnove knjiznice presekov programa WIMS (WIMS Library Updating Project, WLUP). V projektu sodeluje 22 laboratorijev iz 19 drzav, koordiniramo pa ga na Institutu Jozef Stefan. Doslej je koncana faza 1 tega projekta, ki obsega optimizacijo vhodnega modela programa WIMS za pet eksperimentalnih testnih problemov. Podani so tudi rezultati faze 2, v kateri so se procesirali preseki na osnovi ENDF/B-IV datoteke. (author)

  10. Environmental Regulatory Update Table, January--February 1993

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.; Danford, G.S.; Lewis, E.B.

    1993-03-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated bi-monthly with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  11. Environmental Regulatory Update Table, November--December 1993

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.; Danford, G.S.; Lewis, E.B.

    1994-01-01

    The Environmental Regulatory Update Table provides information on regulatory of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated bi-monthly with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  12. Environmental regulatory update table November--December 1994

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Bock, R.E.; Mayer, S.J.; Salk, M.S.

    1995-01-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated bi-monthly with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  13. Environmental Regulatory Update Table, May--June 1994

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Bock, R.E.; Salk, M.S.

    1994-07-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated bimonthly with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  14. Environmental Regulatory Update Table, May/June 1993

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.; Danford, G.S.; Lewis, E.B.

    1993-07-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated bimonthly with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  15. Environmental regulatory update table, March--April 1994

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Bock, R.E. [Oak Ridge National Lab., TN (United States). Health Sciences Research Div.; Salk, M.S. [Oak Ridge National Lab., TN (United States). Environmental Sciences Div.

    1994-03-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated bi-monthly with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  16. Environmental Regulatory Update Table July/August 1993

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.; Danford, G.S.; Lewis, E.B.

    1993-09-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated bi-monthly with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  17. Environmental Regulatory Update Table, March/April 1993

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.; Danford, G.S.; Lewis, E.B.

    1993-05-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated bimonthly with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  18. Environmental Regulatory Update Table, November--December 1992

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Lewis, E.B.; Salk, M.S.

    1993-01-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated bi-monthly wit information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  19. Environmental Regulatory Update Table, July--August 1992

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Lewis, E.B.; Salk, M.S.

    1992-09-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated bi-monthly with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  20. Environmental Regulatory Update Table, September/October 1993

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.; Danford, G.S.; Lewis, E.B.

    1993-11-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operation and contractor staff with environmental management responsibilities. The table is updated bi-monthly with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  1. Environmental Regulatory Update Table, January--February 1994

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.; Danford, G.S.; Lewis, E.B.

    1994-03-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations ad contractor staff with environmental management responsibilities. The table is updated bi-monthly with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  2. Environmental regulatory update table, September--October 1992

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Lewis, E.B.; Salk, M.S.

    1992-11-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated bi-monthly with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  3. Environmental regulatory update table, July/August 1994

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Bock, R.E.; Salk, M.S.

    1994-09-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated bi-monthly with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  4. Environmental Regulatory Update Table, March/April 1992

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.

    1992-05-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated bi-monthly with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action.

  5. Environmental regulatory update table, July/August 1994

    International Nuclear Information System (INIS)

    Houlberg, L.M.; Hawkins, G.T.; Bock, R.E.; Salk, M.S.

    1994-09-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated bi-monthly with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action

  6. Updating radiation protection regulations in Egypt

    International Nuclear Information System (INIS)

    Gomaa, M.A.; El-Naggar, A.M.

    1996-01-01

    The aim of this treatise is to present -the rational steps taken in the process of updating the Radiation Protection Regulations in Egypt. The contents of the review will include a historical synopsis, and the current state of art regarding competent authorities. Furthermore, the various committees formed with responsibilities for specific issues are indicated, including the role of the Ministry of Health (MOH), and that of the Atomic Energy Authority (AEA). Finally, the efforts made towards updating the radiation Protection Regulations in Egypt are highlighted. (author)

  7. National Pediatric Program Update

    International Nuclear Information System (INIS)

    2008-01-01

    The book of the National Pediatric Program Update, issued by the Argentina Society of Pediatrics, describes important issues, including: effective treatment of addictions (drugs); defects of the neural tube; and the use of radiation imaging in diagnosis. [es

  8. 77 FR 33980 - Proposed FOIA Fee Schedule Update

    Science.gov (United States)

    2012-06-08

    ... 1703 Proposed FOIA Fee Schedule Update AGENCY: Defense Nuclear Facilities Safety Board. ACTION: Notice... the Board's proposed FOIA Fee Schedule Update published in the Federal Register of June 1, 2012. The...: The FOIA requires each Federal agency covered by the Act to specify a schedule of fees applicable to...

  9. Clean Coal Technology Programs: Program Update 2009

    Energy Technology Data Exchange (ETDEWEB)

    None

    2009-10-01

    The purpose of the Clean Coal Technology Programs: Program Update 2009 is to provide an updated status of the U.S. Department of Energy (DOE) commercial-scale demonstrations of clean coal technologies (CCT). These demonstrations have been performed under the Clean Coal Technology Demonstration Program (CCTDP), the Power Plant Improvement Initiative (PPII), and the Clean Coal Power Initiative (CCPI). Program Update 2009 provides: (1) a discussion of the role of clean coal technology demonstrations in improving the nation’s energy security and reliability, while protecting the environment using the nation’s most abundant energy resource—coal; (2) a summary of the funding and costs of the demonstrations; and (3) an overview of the technologies being demonstrated, along with fact sheets for projects that are active, recently completed, or recently discontinued.

  10. A local level set method based on a finite element method for unstructured meshes

    International Nuclear Information System (INIS)

    Ngo, Long Cu; Choi, Hyoung Gwon

    2016-01-01

    A local level set method for unstructured meshes has been implemented by using a finite element method. A least-square weighted residual method was employed for implicit discretization to solve the level set advection equation. By contrast, a direct re-initialization method, which is directly applicable to the local level set method for unstructured meshes, was adopted to re-correct the level set function to become a signed distance function after advection. The proposed algorithm was constructed such that the advection and direct reinitialization steps were conducted only for nodes inside the narrow band around the interface. Therefore, in the advection step, the Gauss–Seidel method was used to update the level set function using a node-by-node solution method. Some benchmark problems were solved by using the present local level set method. Numerical results have shown that the proposed algorithm is accurate and efficient in terms of computational time

  11. A local level set method based on a finite element method for unstructured meshes

    Energy Technology Data Exchange (ETDEWEB)

    Ngo, Long Cu; Choi, Hyoung Gwon [School of Mechanical Engineering, Seoul National University of Science and Technology, Seoul (Korea, Republic of)

    2016-12-15

    A local level set method for unstructured meshes has been implemented by using a finite element method. A least-square weighted residual method was employed for implicit discretization to solve the level set advection equation. By contrast, a direct re-initialization method, which is directly applicable to the local level set method for unstructured meshes, was adopted to re-correct the level set function to become a signed distance function after advection. The proposed algorithm was constructed such that the advection and direct reinitialization steps were conducted only for nodes inside the narrow band around the interface. Therefore, in the advection step, the Gauss–Seidel method was used to update the level set function using a node-by-node solution method. Some benchmark problems were solved by using the present local level set method. Numerical results have shown that the proposed algorithm is accurate and efficient in terms of computational time.

  12. Supreme Court Update

    Science.gov (United States)

    Taylor, Kelley R.

    2009-01-01

    "Chief Justice Flubs Oath." "Justice Ginsburg Has Cancer Surgery." At the start of this year, those were the news headlines about the U.S. Supreme Court. But January 2009 also brought news about key education cases--one resolved and two others on the docket--of which school administrators should take particular note. The Supreme Court updates on…

  13. Grey Forecast Rainfall with Flow Updating Algorithm for Real-Time Flood Forecasting

    Directory of Open Access Journals (Sweden)

    Jui-Yi Ho

    2015-04-01

    Full Text Available The dynamic relationship between watershed characteristics and rainfall-runoff has been widely studied in recent decades. Since watershed rainfall-runoff is a non-stationary process, most deterministic flood forecasting approaches are ineffective without the assistance of adaptive algorithms. The purpose of this paper is to propose an effective flow forecasting system that integrates a rainfall forecasting model, watershed runoff model, and real-time updating algorithm. This study adopted a grey rainfall forecasting technique, based on existing hourly rainfall data. A geomorphology-based runoff model can be used for simulating impacts of the changing geo-climatic conditions on the hydrologic response of unsteady and non-linear watershed system, and flow updating algorithm were combined to estimate watershed runoff according to measured flow data. The proposed flood forecasting system was applied to three watersheds; one in the United States and two in Northern Taiwan. Four sets of rainfall-runoff simulations were performed to test the accuracy of the proposed flow forecasting technique. The results indicated that the forecast and observed hydrographs are in good agreement for all three watersheds. The proposed flow forecasting system could assist authorities in minimizing loss of life and property during flood events.

  14. The value of information updating in new product development

    CERN Document Server

    Artmann, Christian

    2009-01-01

    This work shows how managing uncertainty in new product development can be improved by conducting an information update during the development process. The book details the comprehensive model needed to perform that information update.

  15. Risk assessment, management, communication: a guide to selected sources. Update. Information guide

    International Nuclear Information System (INIS)

    1987-05-01

    This is the first update to the March 1987 publication entitled Risk Assessment, Management, Communication: A Guide to Selected Sources. The risk update series is divided into three major sections: Assessment, Management, and Communication. This update also includes subsections on hazardous waste, radiation, and a number of specific chemicals. Due to the expanding literature on risk, other subsections may be added to updates in the future. Each Table of Contents contains a complete list of the subsections. Updates are produced on a quarterly basis

  16. Update History of This Database - DMPD | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us DMPD Update History of This Database Date Update contents 2010/03/29 DMPD English archive si....jp/macrophage/ ) is released. About This Database Database Description Download License Update History of Thi...s Database Site Policy | Contact Us Update History of This Database - DMPD | LSDB Archive ...

  17. Empirical testing of forecast update procedure forseasonal products

    DEFF Research Database (Denmark)

    Wong, Chee Yew; Johansen, John

    2008-01-01

    Updating of forecasts is essential for successful collaborative forecasting, especially for seasonal products. This paper discusses the results of a theoretical simulation and an empirical test of a proposed time-series forecast updating procedure. It involves a two-stage longitudinal case study...... of a toy supply chain. The theoretical simulation involves historical weekly consumer demand data for 122 toy products. The empirical test is then carried out in real-time with 291 toy products. The results show that the proposed forecast updating procedure: 1) reduced forecast errors of the annual...... provided less forecast accuracy improvement and it needed a longer time to achieve relatively acceptable forecast uncertainty....

  18. Distribución condicional de los retornos de la tasa de cambio colombiana: un ejercicio empírico a partir de modelos GARCH univariados.

    Directory of Open Access Journals (Sweden)

    Santiago Gallón Gómez

    2010-05-01

    Full Text Available Un conjunto de modelos GARCH multivariados son estimados y su validez empírica comparada a partir del cálculo de la medida VaR, para los retornos diarios de la tasa de cambio nominal del peso colombiano con respecto al dólar americano, euro, libra esterlina y yen japonés en el periodo 1999–2005. La comparación de las estimaciones para la matriz de covarianza condicional y los resultados obtenidos para la proporción de fallo y el contraste de cuantil dinámico de Engle y Manganelli (2004 presentan evidencia a favor del modelo de correlación condicional constante.

  19. BNL ENVIRONMENTAL MONITORING PLAN TRIENNIAL UPDATE, JANUARY 2003.

    Energy Technology Data Exchange (ETDEWEB)

    BROOKHAVEN NATIONAL LABORATORY

    2003-01-01

    Brookhaven National Laboratory (BNL) is a multi-program national laboratory operated by Brookhaven Science Associates for the U.S. Department of Energy (DOE) and is located on a 5,265-acre site in Suffolk County, Long Island, New York. BNL has a comprehensive Environmental Management System (EMS) in place, which meets the requirements of the International Organization for Standardization 14001 EMS Standard, as described in the BNL EMS Manual. BNL's extensive environmental monitoring program is one component of the EMS, and the BNL Environmental Monitoring Plan (EMP) describes this program in detail. The data derived from systematically monitoring the various environmental media on site enable BNL to make informed decisions concerning the protection of human health and the environment and to be responsive to community concerns.

  20. Update in women's health.

    Science.gov (United States)

    Ganschow, Pamela S; Jacobs, Elizabeth A; Mackinnon, Jennifer; Charney, Pamela

    2009-06-01

    The aim of this clinical update is to summarize articles and guidelines published in the last year with the potential to change current clinical practice as it relates to women's health. We used two independent search strategies to identify articles relevant to women's health published between March 1, 2007 and February 29, 2008. First, we reviewed the Cochrane Database of Systematic Reviews and journal indices from the ACP Journal Club, Annals of Internal Medicine, Archives of Internal Medicine, British Medical Journal, Circulation, Diabetes, JAMA, JGIM, Journal of Women's Health, Lancet, NEJM, Obstetrics and Gynecology, and Women's Health Journal Watch. Second, we performed a MEDLINE search using the medical subject heading term "sex factors." The authors, who all have clinical and/or research experience in the area of women's health, reviewed all article titles, abstracts, and, when indicated, full publications. We excluded articles related to obstetrical aspects of women's health focusing on those relevant to general internists. We had two acceptance criteria, scientific rigor and potential to impact women's health. We also identified new and/or updated women's health guidelines released during the same time period. We identified over 250 publications with potential relevance to women's health. Forty-six articles were selected for presentation as part of the Clinical Update, and nine were selected for a more detailed discussion in this paper. Evidence-based women's health guidelines are listed in Table 1. Table 1 Important Women's Health Guidelines in 2007-2008: New or Updated Topic Issuing organization Updated recommendations and comments Mammography screening in women 40-4917 ACP Individualized risk assessment and informed decision making should be used to guide decisions about mammography screening in this age group. To aid in the risk assessment, a discussion of the risk factors, which if present in a woman in her 40s increases her risk to above that of an

  1. Innovación incremental basada en capacidades dinámicas. Evidencia empírica en las empresas peruanas

    Directory of Open Access Journals (Sweden)

    Alejandro Flores Castro

    2015-09-01

    Full Text Available Los resultados macroeconómicos logrados por el Perú en los últimos años, hacen prever uncrecimiento de la actividad empresarial desde la perspectiva de sus capacidades a fin dealcanzar posiciones de ventaja. Sin embargo, este crecimiento estará basado esencialmenteen procesos de mejora, no vislumbrándose un aporte significativo de parte de las empresasa desarrollar procesos de innovación radical o disruptiva, abocándose preferentemente aprocesos de innovación incremental o de bajo impacto. En la primera parte del documentose aborda el tema de la innovación como factor de ventaja competitiva basado en un modelode capacidades dinámicas, en el contexto de la teoría de recursos y capacidades, analizandolos diferentes modelos de innovación tecnológica. En la segunda parte del trabajo se presentaun modelo de innovación basada en capacidades dinámicas. Y finalmente se presenta lametodología y los resultados del el estudio empírico acerca de los procesos de innovaciónincremental que se dan en las empresas peruanas.

  2. Innovación incremental basada en capacidades dinámicas. Evidencia empírica en las empresas peruanas

    Directory of Open Access Journals (Sweden)

    Alejandro Flores Castro

    2011-06-01

    Full Text Available Los resultados macroeconómicos logrados por el Perú en los últimos años, hacen prever uncrecimiento de la actividad empresarial desde la perspectiva de sus capacidades a fin dealcanzar posiciones de ventaja. Sin embargo, este crecimiento estará basado esencialmenteen procesos de mejora, no vislumbrándose un aporte significativo de parte de las empresasa desarrollar procesos de innovación radical o disruptiva, abocándose preferentemente aprocesos de innovación incremental o de bajo impacto. En la primera parte del documentose aborda el tema de la innovación como factor de ventaja competitiva basado en un modelode capacidades dinámicas, en el contexto de la teoría de recursos y capacidades, analizandolos diferentes modelos de innovación tecnológica. En la segunda parte del trabajo se presentaun modelo de innovación basada en capacidades dinámicas. Y finalmente se presenta lametodología y los resultados del el estudio empírico acerca de los procesos de innovaciónincremental que se dan en las empresas peruanas.

  3. State energy-price system: 1981 update

    Energy Technology Data Exchange (ETDEWEB)

    Fang, J.M.; Imhoff, K.L.; Hood, L.J.

    1983-08-01

    This report updates the State Energy Price Data System (STEPS) to include state-level energy prices by fuel and by end-use sectors for 1981. Both physical unit prices and Btu prices are presented. Basic documentation of the data base remains generally the same as in the original report: State Energy Price System; Volume 1: Overview and Technical Documentation (DOE/NBB-0029 Volume 1 of 2, November 1982). The present report documents only the changes in procedures necessitated by the update to 1981 and the corrections to the basic documentation.

  4. WIMS-D library update

    International Nuclear Information System (INIS)

    2007-05-01

    WIMS-D (Winfrith Improved Multigroup Scheme-D) is the name of a family of software packages for reactor lattice calculations and is one of the few reactor lattice codes in the public domain and available on noncommercial terms. WIMSD-5B has recently been released from the OECD Nuclear Energy Agency Data Bank, and features major improvements in machine portability, as well as incorporating a few minor corrections. This version supersedes WIMS-D/4, which was released by the Winfrith Technology Centre in the United Kingdom for IBM machines and has been adapted for various other computer platforms in different laboratories. The main weakness of the WIMS-D package is the multigroup constants library, which is based on very old data. The relatively good performance of WIMS-D is attributed to a series of empirical adjustments to the multigroup data. However, the adjustments are not always justified on the basis of more accurate and recent experimental measurements. Following the release of new and revised evaluated nuclear data files, it was felt that the performance of WIMS-D could be improved by updating the associated library. The WIMS-D Library Update Project (WLUP) was initiated in the early 1990s with the support of the IAEA. This project consisted of voluntary contributions from a large number of participants. Several benchmarks for testing the library were identified and analysed, the WIMSR module of the NJOY code system was upgraded and the author of NJOY accepted the proposed updates for the official code system distribution. A detailed parametric study was performed to investigate the effects of various data processing input options on the integral results. In addition, the data processing methods for the main reactor materials were optimized. Several partially updated libraries were produced for testing purposes. The final stage of the WLUP was organized as a coordinated research project (CRP) in order to speed up completion of the fully updated library

  5. Who's Who? Memory updating and character reference in children's narratives.

    Science.gov (United States)

    Whitely, Cristy; Colozzo, Paola

    2013-10-01

    The capacity to update and monitor the contents of working memory is an executive function presumed to play a critical role in language processing. The current study used an individual differences approach to consider the relationship between memory updating and accurate reference to story characters in the narratives of typically developing children. English-speaking children from kindergarten to grade 2 ( N = 63; M age = 7.0 years) completed updating tasks, short-term memory tasks, and narrative productions. The authors used multiple regression to test whether updating accounted for independent variability in referential adequacy. The capacity to update working memory was related to adequate character reference beyond the effects of age and of short-term memory capacity, with the strongest relationship emerging for maintaining reference over multiple utterances. This individual differences study is the first to show a link between updating and performance in a discourse production task for young school-age children. The findings contribute to the growing body of research investigating the role of working memory in shaping language production. This study invites extension to children of different ages and language abilities as well as to other language production tasks.

  6. Protocol: An updated integrated methodology for analysis of metabolites and enzyme activities of ethylene biosynthesis

    Directory of Open Access Journals (Sweden)

    Geeraerd Annemie H

    2011-06-01

    Full Text Available Abstract Background The foundations for ethylene research were laid many years ago by researchers such as Lizada, Yang and Hoffman. Nowadays, most of the methods developed by them are still being used. Technological developments since then have led to small but significant improvements, contributing to a more efficient workflow. Despite this, many of these improvements have never been properly documented. Results This article provides an updated, integrated set of protocols suitable for the assembly of a complete picture of ethylene biosynthesis, including the measurement of ethylene itself. The original protocols for the metabolites 1-aminocyclopropane-1-carboxylic acid and 1-(malonylaminocyclopropane-1-carboxylic acid have been updated and downscaled, while protocols to determine in vitro activities of the key enzymes 1-aminocyclopropane-1-carboxylate synthase and 1-aminocyclopropane-1-carboxylate oxidase have been optimised for efficiency, repeatability and accuracy. All the protocols described were optimised for apple fruit, but have been proven to be suitable for the analysis of tomato fruit as well. Conclusions This work collates an integrated set of detailed protocols for the measurement of components of the ethylene biosynthetic pathway, starting from well-established methods. These protocols have been optimised for smaller sample volumes, increased efficiency, repeatability and accuracy. The detailed protocol allows other scientists to rapidly implement these methods in their own laboratories in a consistent and efficient way.

  7. Update History of This Database - DGBY | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us DGBY Update History of This Database Date Update contents 2014/10/20 The URL of the portal s...aro.affrc.go.jp/yakudachi/yeast/index.html ) is opened. About This Database Database Description Download License Update Hi...story of This Database Site Policy | Contact Us Update History of This Database - DGBY | LSDB Archive ... ... Expression of attribution in License is updated. 2012/03/08 DGBY English archive site is opened. 2006/10/02

  8. Why, when and how to update a meta-ethnography qualitative synthesis.

    Science.gov (United States)

    France, Emma F; Wells, Mary; Lang, Heidi; Williams, Brian

    2016-03-15

    Meta-ethnography is a unique, systematic, qualitative synthesis approach widely used to provide robust evidence on patient and clinician beliefs and experiences and understandings of complex social phenomena. It can make important theoretical and conceptual contributions to health care policy and practice. Since beliefs, experiences, health care contexts and social phenomena change over time, the continued relevance of the findings from meta-ethnographies cannot be assumed. However, there is little guidance on whether, when and how meta-ethnographies should be updated; Cochrane guidance on updating reviews of intervention effectiveness is unlikely to be fully appropriate. This is the first in-depth discussion on updating a meta-ethnography; it explores why, when and how to update a meta-ethnography. Three main methods of updating the analysis and synthesis are examined. Advantages and disadvantages of each method are outlined, relating to the context, purpose, process and output of the update and the nature of the new data available. Recommendations are made for the appropriate use of each method, and a worked example of updating a meta-ethnography is provided. This article makes a unique contribution to this evolving area of meta-ethnography methodology.

  9. Working Memory: Maintenance, Updating, and the Realization of Intentions

    Science.gov (United States)

    Nyberg, Lars; Eriksson, Johan

    2016-01-01

    “Working memory” refers to a vast set of mnemonic processes and associated brain networks, relates to basic intellectual abilities, and underlies many real-world functions. Working-memory maintenance involves frontoparietal regions and distributed representational areas, and can be based on persistent activity in reentrant loops, synchronous oscillations, or changes in synaptic strength. Manipulation of content of working memory depends on the dorsofrontal cortex, and updating is realized by a frontostriatal ‘“gating” function. Goals and intentions are represented as cognitive and motivational contexts in the rostrofrontal cortex. Different working-memory networks are linked via associative reinforcement-learning mechanisms into a self-organizing system. Normal capacity variation, as well as working-memory deficits, can largely be accounted for by the effectiveness and integrity of the basal ganglia and dopaminergic neurotransmission. PMID:26637287

  10. Updated and revised neutron reaction data for 237Np

    Directory of Open Access Journals (Sweden)

    Chen Guochang

    2017-01-01

    Full Text Available Nuclear data with high accuracy for minor actinides play an important role in nuclear technology applications, including reactor design and operation, fuel cycle, estimation of the amount of minor actinides in high burn-up reactors and the minor actinides transmutation. Based on the evaluated experimental data, the updated and revised evaluation of a full set of n+237Np nuclear data from 10−5 eV ∼ 20 MeV are carried out and recommended. Mainly revised quantities are neutron multiplicities from fission reaction, inelastic, fission, (n, 2n and (n, γ reaction cross sections as well as angular distribution and so on. The promising results are obtained when the renewal evaluated data of 237Np will be used to instead of the evaluated data in CENDL-3.1 database.

  11. 32 CFR 635.24 - Updating the COPS MPRS.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Updating the COPS MPRS. 635.24 Section 635.24 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW ENFORCEMENT AND CRIMINAL INVESTIGATIONS LAW ENFORCEMENT REPORTING Offense Reporting § 635.24 Updating the COPS MPRS. Installation Provost Marshals/Directors of...

  12. Persistencia y capacidad predictiva de márgenes y rotaciones. un análisis empírico

    Directory of Open Access Journals (Sweden)

    Juan Monterrey

    2011-01-01

    Full Text Available En el presente trabajo abordamos el estudio empírico de la persistencia y capacidad predictiva de los componentes margen y rotación de la rentabilidad. A partir de una amplia muestra de compañías españolas, hemos documentado cómo la persistencia de la rotación es superior a la del margen, y cómo los componentes anormales de margen y rotación son menos persistentes que sus componentes sectoriales. Con relación a la capacidad predictiva, nuestros hallazgos confirman que el poder de predicción del margen es más elevado que el de la rotación, aunque su persistencia sea menor. Al separar los componentes sectorial y anormal de margen y rotación hemos comprobado cómo los componentes anormales muestran una capacidad predictiva superior a los componentes sectoriales. Los análisis complementarios muestran el distinto poder predictivo según el signo positivo o negativo de márgenes y rotaciones anormales, y según el signo del resultado, así como la robustez de nuestros hallazgos.

  13. Sequence History Update Tool

    Science.gov (United States)

    Khanampompan, Teerapat; Gladden, Roy; Fisher, Forest; DelGuercio, Chris

    2008-01-01

    The Sequence History Update Tool performs Web-based sequence statistics archiving for Mars Reconnaissance Orbiter (MRO). Using a single UNIX command, the software takes advantage of sequencing conventions to automatically extract the needed statistics from multiple files. This information is then used to populate a PHP database, which is then seamlessly formatted into a dynamic Web page. This tool replaces a previous tedious and error-prone process of manually editing HTML code to construct a Web-based table. Because the tool manages all of the statistics gathering and file delivery to and from multiple data sources spread across multiple servers, there is also a considerable time and effort savings. With the use of The Sequence History Update Tool what previously took minutes is now done in less than 30 seconds, and now provides a more accurate archival record of the sequence commanding for MRO.

  14. Update History of This Database - SAHG | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us SAHG Update History of This Database Date Update contents 2016/05/09 SAHG English archive si...te is opened. 2009/10 SAHG ( http://bird.cbrc.jp/sahg ) is opened. About This Database Database Description ...Download License Update History of This Database Site Policy | Contact Us Update History of This Database - SAHG | LSDB Archive ...

  15. Update History of This Database - RMOS | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us RMOS Update History of This Database Date Update contents 2015/10/27 RMOS English archive si...12 RMOS (http://cdna01.dna.affrc.go.jp/RMOS/) is opened. About This Database Database Description Download License Update Hi...story of This Database Site Policy | Contact Us Update History of This Database - RMOS | LSDB Archive ...

  16. 2016 Updated American Society of Clinical Oncology/Oncology Nursing Society Chemotherapy Administration Safety Standards, Including Standards for Pediatric Oncology.

    Science.gov (United States)

    Neuss, Michael N; Gilmore, Terry R; Belderson, Kristin M; Billett, Amy L; Conti-Kalchik, Tara; Harvey, Brittany E; Hendricks, Carolyn; LeFebvre, Kristine B; Mangu, Pamela B; McNiff, Kristen; Olsen, MiKaela; Schulmeister, Lisa; Von Gehr, Ann; Polovich, Martha

    2016-12-01

    Purpose To update the ASCO/Oncology Nursing Society (ONS) Chemotherapy Administration Safety Standards and to highlight standards for pediatric oncology. Methods The ASCO/ONS Chemotherapy Administration Safety Standards were first published in 2009 and updated in 2011 to include inpatient settings. A subsequent 2013 revision expanded the standards to include the safe administration and management of oral chemotherapy. A joint ASCO/ONS workshop with stakeholder participation, including that of the Association of Pediatric Hematology Oncology Nurses and American Society of Pediatric Hematology/Oncology, was held on May 12, 2015, to review the 2013 standards. An extensive literature search was subsequently conducted, and public comments on the revised draft standards were solicited. Results The updated 2016 standards presented here include clarification and expansion of existing standards to include pediatric oncology and to introduce new standards: most notably, two-person verification of chemotherapy preparation processes, administration of vinca alkaloids via minibags in facilities in which intrathecal medications are administered, and labeling of medications dispensed from the health care setting to be taken by the patient at home. The standards were reordered and renumbered to align with the sequential processes of chemotherapy prescription, preparation, and administration. Several standards were separated into their respective components for clarity and to facilitate measurement of adherence to a standard. Conclusion As oncology practice has changed, so have chemotherapy administration safety standards. Advances in technology, cancer treatment, and education and training have prompted the need for periodic review and revision of the standards. Additional information is available at http://www.asco.org/chemo-standards .

  17. Environmental Regulatory Update Table, January/February 1992

    Energy Technology Data Exchange (ETDEWEB)

    Houlberg, L.M.; Hawkins, G.T.; Salk, M.S.

    1992-03-01

    The Environmental Regulatory Update Table provides information on regulatory initiatives of interest to DOE operations and contractor staff with environmental management responsibilities. The table is updated bi-monthly with information from the Federal Register and other sources, including direct contact with regulatory agencies. Each table entry provides a chronological record of the rulemaking process for that initiative with an abstract and a projection of further action. This table is for January/February 1992.

  18. Integrated information theory of consciousness: an updated account.

    Science.gov (United States)

    Tononi, G

    2012-12-01

    This article presents an updated account of integrated information theory of consciousness (liT) and some of its implications. /IT stems from thought experiments that lead to phenomenological axioms (existence, compositionality, information, integration, exclusion) and corresponding ontological postulates. The information axiom asserts that every experience is spec~fic - it is what it is by differing in its particular way from a large repertoire of alternatives. The integration axiom asserts that each experience is unified- it cannot be reduced to independent components. The exclusion axiom asserts that every experience is definite - it is limited to particular things and not others and flows at a particular speed and resolution. /IT formalizes these intuitions with postulates. The information postulate states that only "differences that make a difference" from the intrinsic perpective of a system matter: a mechanism generates cause-effect information if its present state has selective past causes and selective future effects within a system. The integration postulate states that only information that is irreducible matters: mechanisms generate integrated information only to the extent that the information they generate cannot be partitioned into that generated within independent components. The exclusion postulate states that only maxima of integrated information matter: a mechanism specifies only one maximally irreducible set of past causes and future effects - a concept. A complex is a set of elements specifying a maximally irreducible constellation of concepts, where the maximum is evaluated over elements and at the optimal spatiatemporal scale. Its concepts specify a maximally integrated conceptual information structure or quale, which is identical with an experience. Finally, changes in information integration upon exposure to the environment reflect a system's ability to match the causal structure of the world. After introducing an updated definition of

  19. Updated radio Σ−D relation for galactic supernova remnants

    Directory of Open Access Journals (Sweden)

    Pavlović M.Z.

    2014-01-01

    Full Text Available We present the updated empirical radio surface-brightness-to-diameter (Σ − D relation for supernova remnants (SNRs in our Galaxy. Our original calibration sample of Galactic SNRs with independently determined distances (Pavlović et al. 2013, hereafter Paper I is reconsidered and updated with data which became available in the past two years. The orthogonal fitting procedure and probability-density-function-based (PDF method are applied to the calibration sample in the logΣ − logD plane. Non-standard orthogonal regression keeps the Σ−D and D−Σ relations invariant within estimated uncertainties. Our previous Monte Carlo simulations verified that the slopes of the empirical Σ−D relation should be determined by using the orthogonal regression, because of its good performances for data sets with severe scatter. The updated calibration sample contains 65 shell SNRs. 6 new Galactic SNRs are added to the sample from Paper I, one is omitted and distances are changed for 10 SNRs. The slope derived is here slightly steeper (β ≈ 5.2 than the Σ−D slope in Paper I (β ≈ 4.8. The PDF method relies on data points density maps which can provide more reliable calibrations that preserve more information contained in the calibration sample. We estimate distances to five new faint Galactic SNRs discovered for the first time by Canadian Galactic Plane Survey, and obtained distances of 2.3, 4.0, 1.3, 2.9 and 4.7 kiloparsecs for G108.5+11.0, G128.5+2.6, G149.5+3.2, G150.8+3.8 and G160.1−1.1, respectively. The updated empirical relation is used to estimate distances of 160 shell Galactic SNRs and new results change their distance scales up to 15 per cent, compared to the results from Paper I. The PDF calculation can provide even few times higher or lower values in comparison with the orthogonal fit, as it uses a totally different approach. However, on average, this difference is 32, 24 and 18 per cent for mode, median and mean distances

  20. Evidence-based guideline update

    DEFF Research Database (Denmark)

    Tfelt-Hansen, Peer Carsten

    2013-01-01

    Peer Carsten Tfelt-Hansen, Glostrup, Denmark: According to the recent American Academy of Neurology (AAN) guideline update, a drug can be recommended as possibly effective for migraine prevention if it had demonstrated efficacy in one Class II study.(1) Eight drugs are recommended as possibly...

  1. Update History of This Database - SSBD | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us SSBD Update History of This Database Date Update contents 2016/07/25 SSBD English archive si...tion Download License Update History of This Database Site Policy | Contact Us Update History of This Database - SSBD | LSDB Archive ... ...te is opened. 2013/09/03 SSBD ( http://ssbd.qbic.riken.jp/ ) is opened. About This Database Database Descrip

  2. Q2/Q3 2017 Solar Industry Update

    Energy Technology Data Exchange (ETDEWEB)

    Feldman, David J. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Hoskins, Jack [Dept. of Energy (DOE), Washington DC (United States); Margolis, Robert M. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2017-10-24

    This technical presentation provides an update on the major trends that occurred in the solar industry in Q2 and Q3 of 2017. Major topics of focus include global and U.S. supply and demand, module and system price, investment trends and business models, and updates on U.S. government programs supporting the solar industry.

  3. Q2/Q3 2016 Solar Industry Update

    Energy Technology Data Exchange (ETDEWEB)

    Feldman, David; Boff, Daniel; Margolis, Robert

    2016-10-11

    This technical presentation provides an update on the major trends that occurred in the solar industry in the Q2 and Q3 of 2016. Major topics of focus include global and U.S. supply and demand, module and system price, investment trends and business models, and updates on U.S. government programs supporting the solar industry.

  4. Q3/Q4 2016 Solar Industry Update

    Energy Technology Data Exchange (ETDEWEB)

    Feldman, David; Boff, Daniel; Margolis, Robert

    2016-12-21

    This technical presentation provides an update on the major trends that occurred in the solar industry in the Q3 and Q4 of 2016. Major topics of focus include global and U.S. supply and demand, module and system price, investment trends and business models, and updates on U.S. government programs supporting the solar industry.

  5. Q3/Q4 2017 Solar Industry Update

    Energy Technology Data Exchange (ETDEWEB)

    Feldman, David J. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Hoskins, Jack [Dept. of Energy (DOE), Washington DC (United States); Margolis, Robert M. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2018-02-15

    This technical presentation provides an update on the major trends that occurred in the solar industry in the Q3 and Q4 of 2017. Major topics of focus include global and U.S. supply and demand, module and system price, investment trends and business models, and updates on U.S. government programs supporting the solar industry.

  6. Review and update of mutations causing Waardenburg syndrome.

    Science.gov (United States)

    Pingault, Véronique; Ente, Dorothée; Dastot-Le Moal, Florence; Goossens, Michel; Marlin, Sandrine; Bondurand, Nadège

    2010-04-01

    Waardenburg syndrome (WS) is characterized by the association of pigmentation abnormalities, including depigmented patches of the skin and hair, vivid blue eyes or heterochromia irides, and sensorineural hearing loss. However, other features such as dystopia canthorum, musculoskeletal abnormalities of the limbs, Hirschsprung disease, or neurological defects are found in subsets of patients and used for the clinical classification of WS. Six genes are involved in this syndrome: PAX3 (encoding the paired box 3 transcription factor), MITF (microphthalmia-associated transcription factor), EDN3 (endothelin 3), EDNRB (endothelin receptor type B), SOX10 (encoding the Sry bOX10 transcription factor), and SNAI2 (snail homolog 2), with different frequencies. In this review we provide an update on all WS genes and set up mutation databases, summarize molecular and functional data available for each of them, and discuss the applications in diagnostics and genetic counseling. (c) 2010 Wiley-Liss, Inc.

  7. TAM 2.0: tool for MicroRNA set analysis.

    Science.gov (United States)

    Li, Jianwei; Han, Xiaofen; Wan, Yanping; Zhang, Shan; Zhao, Yingshu; Fan, Rui; Cui, Qinghua; Zhou, Yuan

    2018-06-06

    With the rapid accumulation of high-throughput microRNA (miRNA) expression profile, the up-to-date resource for analyzing the functional and disease associations of miRNAs is increasingly demanded. We here describe the updated server TAM 2.0 for miRNA set enrichment analysis. Through manual curation of over 9000 papers, a more than two-fold growth of reference miRNA sets has been achieved in comparison with previous TAM, which covers 9945 and 1584 newly collected miRNA-disease and miRNA-function associations, respectively. Moreover, TAM 2.0 allows users not only to test the functional and disease annotations of miRNAs by overrepresentation analysis, but also to compare the input de-regulated miRNAs with those de-regulated in other disease conditions via correlation analysis. Finally, the functions for miRNA set query and result visualization are also enabled in the TAM 2.0 server to facilitate the community. The TAM 2.0 web server is freely accessible at http://www.scse.hebut.edu.cn/tam/ or http://www.lirmed.com/tam2/.

  8. Updating of visual orientation in a gravity-based reference frame.

    Science.gov (United States)

    Niehof, Nynke; Tramper, Julian J; Doeller, Christian F; Medendorp, W Pieter

    2017-10-01

    The brain can use multiple reference frames to code line orientation, including head-, object-, and gravity-centered references. If these frames change orientation, their representations must be updated to keep register with actual line orientation. We tested this internal updating during head rotation in roll, exploiting the rod-and-frame effect: The illusory tilt of a vertical line surrounded by a tilted visual frame. If line orientation is stored relative to gravity, these distortions should also affect the updating process. Alternatively, if coding is head- or frame-centered, updating errors should be related to the changes in their orientation. Ten subjects were instructed to memorize the orientation of a briefly flashed line, surrounded by a tilted visual frame, then rotate their head, and subsequently judge the orientation of a second line relative to the memorized first while the frame was upright. Results showed that updating errors were mostly related to the amount of subjective distortion of gravity at both the initial and final head orientation, rather than to the amount of intervening head rotation. In some subjects, a smaller part of the updating error was also related to the change of visual frame orientation. We conclude that the brain relies primarily on a gravity-based reference to remember line orientation during head roll.

  9. [Preoperative fasting guidelines: an update].

    Science.gov (United States)

    López Muñoz, A C; Busto Aguirreurreta, N; Tomás Braulio, J

    2015-03-01

    Anesthesiology societies have issued various guidelines on preoperative fasting since 1990, not only to decrease the incidence of lung aspiration and anesthetic morbidity, but also to increase patient comfort prior to anesthesia. Some of these societies have been updating their guidelines, as such that, since 2010, we now have 2 evidence-based preoperative fasting guidelines available. In this article, an attempt is made to review these updated guidelines, as well as the current instructions for more controversial patients such as infants, the obese, and a particular type of ophthalmic surgery. Copyright © 2014 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Publicado por Elsevier España, S.L.U. All rights reserved.

  10. Effects of lateral boundary condition resolution and update frequency on regional climate model predictions

    Science.gov (United States)

    Pankatz, Klaus; Kerkweg, Astrid

    2015-04-01

    The work presented is part of the joint project "DecReg" ("Regional decadal predictability") which is in turn part of the project "MiKlip" ("Decadal predictions"), an effort funded by the German Federal Ministry of Education and Research to improve decadal predictions on a global and regional scale. In MiKlip, one big question is if regional climate modeling shows "added value", i.e. to evaluate, if regional climate models (RCM) produce better results than the driving models. However, the scope of this study is to look more closely at the setup specific details of regional climate modeling. As regional models only simulate a small domain, they have to inherit information about the state of the atmosphere at their lateral boundaries from external data sets. There are many unresolved questions concerning the setup of lateral boundary conditions (LBC). External data sets come from global models or from global reanalysis data-sets. A temporal resolution of six hours is common for this kind of data. This is mainly due to the fact, that storage space is a limiting factor, especially for climate simulations. However, theoretically, the coupling frequency could be as high as the time step of the driving model. Meanwhile, it is unclear if a more frequent update of the LBCs has a significant effect on the climate in the domain of the RCM. The first study examines how the RCM reacts to a higher update frequency. The study is based on a 30 year time slice experiment for three update frequencies of the LBC, namely six hours, one hour and six minutes. The evaluation of means, standard deviations and statistics of the climate in the regional domain shows only small deviations, some statistically significant though, of 2m temperature, sea level pressure and precipitation. The second part of the first study assesses parameters linked to cyclone activity, which is affected by the LBC update frequency. Differences in track density and strength are found when comparing the simulations

  11. Follow up: Compound data sets and software tools for chemoinformatics and medicinal chemistry applications: update and data transfer

    Science.gov (United States)

    Hu, Ye; Bajorath, Jürgen

    2014-01-01

    In 2012, we reported 30 compound data sets and/or programs developed in our laboratory in a data article and made them freely available to the scientific community to support chemoinformatics and computational medicinal chemistry applications. These data sets and computational tools were provided for download from our website. Since publication of this data article, we have generated 13 new data sets with which we further extend our collection of publicly available data and tools. Due to changes in web servers and website architectures, data accessibility has recently been limited at times. Therefore, we have also transferred our data sets and tools to a public repository to ensure full and stable accessibility. To aid in data selection, we have classified the data sets according to scientific subject areas. Herein, we describe new data sets, introduce the data organization scheme, summarize the database content and provide detailed access information in ZENODO (doi: 10.5281/zenodo.8451 and doi:10.5281/zenodo.8455). PMID:25520777

  12. Cassini Spacecraft Uncertainty Analysis Data and Methodology Review and Update/Volume 1: Updated Parameter Uncertainty Models for the Consequence Analysis

    Energy Technology Data Exchange (ETDEWEB)

    WHEELER, TIMOTHY A.; WYSS, GREGORY D.; HARPER, FREDERICK T.

    2000-11-01

    Uncertainty distributions for specific parameters of the Cassini General Purpose Heat Source Radioisotope Thermoelectric Generator (GPHS-RTG) Final Safety Analysis Report consequence risk analysis were revised and updated. The revisions and updates were done for all consequence parameters for which relevant information exists from the joint project on Probabilistic Accident Consequence Uncertainty Analysis by the United States Nuclear Regulatory Commission and the Commission of European Communities.

  13. Productividad de recursos humanos, innovación de producto y desempeño exportador: Una investigación empírica

    Directory of Open Access Journals (Sweden)

    Rafael Reina Valle

    2016-04-01

    Full Text Available Objeto: El objetivo de esta investigación es examinar las relaciones entre la productividad de los recursos humanos (RRHH, la innovación de productos y el desempeño exportador de la PYME manufacturera española. Diseño/metodología: La proposición central de esta investigación es que la productividad de los RRHH facilita el desarrollo de innovaciones de producto para incrementar el desempeño exportador de las empresas. El modelo conceptual propuesto se contrasta empleando la técnica de la modelización de ecuaciones estructurales basada en la varianza y el método de estimación de los mínimos cuadrados parciales, sobre una muestra de 858 PYMES manufactureras españolas. Aportaciones y resultados: El análisis empírico da apoyo a la proposición central e indica que la productividad de los RRHH facilita el desarrollo de innovaciones de producto para incrementar el desempeño exportador. Limitaciones: Esta investigación sólo se centra en el rol de la innovación de producto en la relación entre la productividad de los RRHH y el desempeño exportador. También sería interesante estudiar el papel mediador de capacidades organizativas basadas en otros tipos de innovaciones  (p.e., la innovación en procesos, organizativa o en marketing. Implicaciones prácticas: Sugerir a los empresarios de PYMES que incrementos  en la productividad de los RRHH puede llevar a que dichos impactos sean capturados por la innovación dando lugar a la generación de nuevos productos, que conllevará shocks de demanda, y en consecuencia de un mayor incremento de la exportación de sus empresas. Valor añadido: Esta investigación explica conceptualmente y demuestra empíricamente que la innovación de producto es un mecanismo intermedio clave, a través del cual, la mayor productividad de los RRHH se convierte en un mayor desempeño exportador de la PYME manufacturera española.

  14. Update History of This Database - RED | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us RED Update History of This Database Date Update contents 2015/12/21 Rice Expression Database English archi...s Database Database Description Download License Update History of This Database Site Policy | Contact Us Update History of This Database - RED | LSDB Archive ... ...ve site is opened. 2000/10/1 Rice Expression Database ( http://red.dna.affrc.go.jp/RED/ ) is opened. About Thi

  15. Selective updating of working memory content modulates meso-cortico-striatal activity.

    Science.gov (United States)

    Murty, Vishnu P; Sambataro, Fabio; Radulescu, Eugenia; Altamura, Mario; Iudicello, Jennifer; Zoltick, Bradley; Weinberger, Daniel R; Goldberg, Terry E; Mattay, Venkata S

    2011-08-01

    Accumulating evidence from non-human primates and computational modeling suggests that dopaminergic signals arising from the midbrain (substantia nigra/ventral tegmental area) mediate striatal gating of the prefrontal cortex during the selective updating of working memory. Using event-related functional magnetic resonance imaging, we explored the neural mechanisms underlying the selective updating of information stored in working memory. Participants were scanned during a novel working memory task that parses the neurophysiology underlying working memory maintenance, overwriting, and selective updating. Analyses revealed a functionally coupled network consisting of a midbrain region encompassing the substantia nigra/ventral tegmental area, caudate, and dorsolateral prefrontal cortex that was selectively engaged during working memory updating compared to the overwriting and maintenance of working memory content. Further analysis revealed differential midbrain-dorsolateral prefrontal interactions during selective updating between low-performing and high-performing individuals. These findings highlight the role of this meso-cortico-striatal circuitry during the selective updating of working memory in humans, which complements previous research in behavioral neuroscience and computational modeling. Published by Elsevier Inc.

  16. Second update The Gordon Bell Competition entry gb110s2

    International Nuclear Information System (INIS)

    Vranas, P; Soltz, R

    2006-01-01

    Since the update to our entry of October 20th we have just made a significant improvement. We understand that this is past the deadline for updates and very close to the conference date. However, Lawrence Livermore National Laboratory has just updated the BG/L system software on their full 64 BG/L supercomputer to IBM-BGL Release 3. As we discussed in our update of October 20 this release includes our custom L1 and SRAM access functions that allow us to achieve higher sustained performance. Just a few hours ago we got access to the full system and obtained the fastest sustained performance point. In the full 131,072 CPU-cores system QCD sustains 70.9 Teraflops for the Dirac operator and 67.9 teraflops for the full Conjugate Gradient inverter. This is about 20% faster than our last update. We attach the corresponding speedup figure. As you can tell the speedup is perfect. This figure is the same as Figure 1 of our October 20th update except that it now includes the 131,072 CPU-cores point

  17. Evolution of ERP Systems in the Cloud: A Study on System Updates

    Directory of Open Access Journals (Sweden)

    Elise Bjelland

    2018-06-01

    Full Text Available Cloud-based enterprise resource planning (ERP systems emerged around the new millennium, and since then there has been a lack of research regarding the evolution and update processes of these systems. From the users’ perspective, updates in a traditional on-premise ERP system are carried at their own request; while cloud-based ERPs are compulsory updated. Through an established ERP lifecycle framework, this study investigates how the process of updates is conducted in a cloud ERP context, from both the users’ and vendors’ perspectives. A multiple case study was conducted in Norway at 10 client organizations, as well as a cloud ERP vendor. Our main findings suggest that the vendor and the users view the process of updates differently. The main challenges with the process of updates from the users’ perspective are the size and date of the updates, lack of information and communication during the process, and extinction of certain functionalities. Yet, the main advantages are that all system users will always have the same version of the system, users do not need to spend time on updating the system and paying attention to the ERP market, which leads to more focus on their core competences instead.

  18. CO2 line-mixing database and software update and its tests in the 2.1 μm and 4.3 μm regions

    International Nuclear Information System (INIS)

    Lamouroux, J.; Régalia, L.; Thomas, X.; Vander Auwera, J.; Gamache, R.R.; Hartmann, J.-M.

    2015-01-01

    An update of the former version of the database and software for the calculation of CO 2 –air absorption coefficients taking line-mixing into account [Lamouroux et al. J Quant Spectrosc Radiat Transf 2010;111:2321] is described. In this new edition, the data sets were constructed using parameters from the 2012 version of the HITRAN database and recent measurements of line-shape parameters. Among other improvements, speed-dependent profiles can now be used if line-mixing is treated within the first order approximation. This new package is tested using laboratory spectra measured in the 2.1 μm and 4.3 μm spectral regions for various pressures, temperatures and CO 2 concentration conditions. Despite improvements at 4.3 μm at room temperature, the conclusions on the quality of this update are more ambiguous at low temperature and in the 2.1 μm region. Further tests using laboratory and atmospheric spectra are thus required for the evaluation of the performances of this updated package. - Highlights: • High resolution infrared spectroscopy. • CO 2 in air. • Updated tools. • Line mixing database and software

  19. Empirical evidence of S-curves in the Colombian Evidencia empírica de la curva S en las balanzas comerciales bilaterales de Colombia

    Directory of Open Access Journals (Sweden)

    Lorena Andrea Palacios-Chacón

    2012-06-01

    Full Text Available The Marshall-Lerner condition, the J-curve and S-curve have emerged as theoretical  and empirical foundations developed for the study of the interaction between exchange rates and international patterns of bilateral trade. They have a significant bearing on thedevelopment of public policy, and are of equal interest to the academic and professional communities. The most recently developed of these theories, the S-Curve, is named after the theorized short-run behavior to be found in the cross-correlation function of the real exchange rate and the trade balance. Considering this theoretical context, the paper seeks empirical evidence of the existence of the S-Curve in the bilateral trade in commodity and non-commodity goods between Colombia and the United States and Venezuela, its main trading partners, for the yearly quarters between 1994:1 and 2009:4.La condición Marshall-Lerner la curva J y la curva S han surgido como elementos teóricos y empíricos desarrollados para el estudio de la interacción entre las tasas de cambio y los patrones internacionales de comercio bilateral. Estas poseen una relevancia significativa en el desarrollo de política pública nacional y han sido objeto de estudio por la comunidad académica y profesional. La más reciente de estas teorías, la curva S, se conoce como la conducta que se teoriza hallar en la función de correlación cruzada entre la tasa de cambio real y la balanza comercial a corto plazo. Basado en dicho contexto teórico, este artículo busca evidencia empírica sobre la existencia de la curva S en el intercambio comercial bilateral de bienes commodities y non-commodities entre Colombia y Estados Unidos y Venezuela, sus principales socios comerciales, en los trimestres entre 1994:1 y 2009:4.

  20. Update History of This Database - RPD | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us RPD Update History of This Database Date Update contents 2016/02/02 Rice Proteome Database English archi...s Database Database Description Download License Update History of This Database Site Policy | Contact Us Update History of This Database - RPD | LSDB Archive ... ...ve site is opened. 2003/01/07 Rice Proteome Database ( http://gene64.dna.affrc.go.jp/RPD/ ) is opened. About Thi

  1. Update History of This Database - PLACE | LSDB Archive [Life Science Database Archive metadata

    Lifescience Database Archive (English)

    Full Text Available switchLanguage; BLAST Search Image Search Home About Archive Update History Data ...List Contact us PLACE Update History of This Database Date Update contents 2016/08/22 The contact address is...s Database Database Description Download License Update History of Thi...s Database Site Policy | Contact Us Update History of This Database - PLACE | LSDB Archive ... ... changed. 2014/10/20 The URLs of the database maintenance site and the portal site are changed. 2014/07/17 PLACE English archi

  2. 77 FR 19077 - Adoption of Updated EDGAR Filer Manual

    Science.gov (United States)

    2012-03-30

    ... practice, publication for notice and comment is not required under the Administrative Procedure Act (APA...-30008] Adoption of Updated EDGAR Filer Manual AGENCY: Securities and Exchange Commission. ACTION: Final... Electronic Data Gathering, Analysis, and Retrieval System (EDGAR) Filer Manual to reflect updates to the...

  3. 76 FR 73506 - Adoption of Updated EDGAR Filer Manual

    Science.gov (United States)

    2011-11-29

    ... practice, publication for notice and comment is not required under the Administrative Procedure Act (APA...-29868] Adoption of Updated EDGAR Filer Manual AGENCY: Securities and Exchange Commission. ACTION: Final... Electronic Data Gathering, Analysis, and Retrieval System (EDGAR) Filer Manual to reflect updates to the...

  4. 77 FR 71089 - Pilot Loading of Aeronautical Database Updates

    Science.gov (United States)

    2012-11-29

    ...) card, rather than in resident memory. The database update was accomplished by removing the SD card with... frequency distance measuring equipment (DME), and any updates that affect system operating software--that... developed with attention to data integrity. Current technology uses databases which are developed in...

  5. LBTool: A stochastic toolkit for leave-based key updates

    DEFF Research Database (Denmark)

    Yuksel, Ender; Nielson, Hanne Riis; Nielson, Flemming

    2012-01-01

    Quantitative techniques have been successfully employed in verification of information and communication systems. However, the use of such techniques are still rare in the area of security. In this paper, we present a toolkit that implements transient analysis on a key update method for wireless...... sensor networks. The analysis aims to find out the probability of a network key being compromised at a specific time point, which result in fluctuations over time for a specific key update method called Leave-based key update. For such a problem, the use of current tools is limited in many ways...

  6. Nevada Nuclear Waste Storage Investigations, January-June 1987: An update

    International Nuclear Information System (INIS)

    Tamura, A.T.; Lorenz, J.J.

    1988-03-01

    This update contains information on the Nevada Nuclear Waste Storage Investigations (NNWSI) that was added to the DOE Energy Data Base during the first six months of 1987. The update is categorized by principal NNWSI Project participating organization, and items are arranged in chronological order. Participant-sponsored subcontractor reports, papers, and articles are included in the sponsoring organization's list. The publication following this update will be a supplement to the first bibliography (DOE/TIC-3406) and will include all information retrieved from January 1, 1986, to December 31, 1987. It will be a cumulation of all updates for this two-year interval and will include indexing for: Corporate Author, Personal Author, Subject, Contract Number, Report Number, Order Number Correlation, and Key Word in Context

  7. Set-theoretic methods in control

    CERN Document Server

    Blanchini, Franco

    2015-01-01

    The second edition of this monograph describes the set-theoretic approach for the control and analysis of dynamic systems, both from a theoretical and practical standpoint.  This approach is linked to fundamental control problems, such as Lyapunov stability analysis and stabilization, optimal control, control under constraints, persistent disturbance rejection, and uncertain systems analysis and synthesis.  Completely self-contained, this book provides a solid foundation of mathematical techniques and applications, extensive references to the relevant literature, and numerous avenues for further theoretical study. All the material from the first edition has been updated to reflect the most recent developments in the field, and a new chapter on switching systems has been added.  Each chapter contains examples, case studies, and exercises to allow for a better understanding of theoretical concepts by practical application. The mathematical language is kept to the minimum level necessary for the adequate for...

  8. In Vitro Variant Surface Antigen Expression in Plasmodium falciparum Parasites from a Semi-Immune Individual Is Not Correlated with Var Gene Transcription

    Science.gov (United States)

    Tschan, Serena; Flötenmeyer, Matthias; Koch, Iris; Berger, Jürgen; Kremsner, Peter; Frank, Matthias

    2016-01-01

    Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is considered to be the main variant surface antigen (VSA) of Plasmodium falciparum and is mainly localized on electron-dense knobs in the membrane of the infected erythrocyte. Switches in PfEMP1 expression provide the basis for antigenic variation and are thought to be critical for parasite persistence during chronic infections. Recently, strain transcending anti-PfEMP1 immunity has been shown to develop early in life, challenging the role of PfEMP1 in antigenic variation during chronic infections. In this work we investigate how P. falciparum achieves persistence during a chronic asymptomatic infection. The infected individual (MOA) was parasitemic for 42 days and multilocus var gene genotyping showed persistence of the same parasite population throughout the infection. Parasites from the beginning of the infection were adapted to tissue culture and cloned by limiting dilution. Flow cytometry using convalescent serum detected a variable surface recognition signal on isogenic clonal parasites. Quantitative real-time PCR with a field isolate specific var gene primer set showed that the surface recognition signal was not correlated with transcription of individual var genes. Strain transcending anti-PfEMP1 immunity of the convalescent serum was demonstrated with CD36 selected and PfEMP1 knock-down NF54 clones. In contrast, knock-down of PfEMP1 did not have an effect on the antibody recognition signal in MOA clones. Trypsinisation of the membrane surface proteins abolished the surface recognition signal and immune electron microscopy revealed that antibodies from the convalescent serum bound to membrane areas without knobs and with knobs. Together the data indicate that PfEMP1 is not the main variable surface antigen during a chronic infection and suggest a role for trypsin sensitive non-PfEMP1 VSAs for parasite persistence in chronic infections. PMID:27907004

  9. On low-rank updates to the singular value and Tucker decompositions

    Energy Technology Data Exchange (ETDEWEB)

    O' Hara, M J

    2009-10-06

    The singular value decomposition is widely used in signal processing and data mining. Since the data often arrives in a stream, the problem of updating matrix decompositions under low-rank modification has been widely studied. Brand developed a technique in 2006 that has many advantages. However, the technique does not directly approximate the updated matrix, but rather its previous low-rank approximation added to the new update, which needs justification. Further, the technique is still too slow for large information processing problems. We show that the technique minimizes the change in error per update, so if the error is small initially it remains small. We show that an updating algorithm for large sparse matrices should be sub-linear in the matrix dimension in order to be practical for large problems, and demonstrate a simple modification to the original technique that meets the requirements.

  10. Empātijas atšķirības improvizācijas teātru, amatierteātru un koru dalībniekiem

    OpenAIRE

    Nikolajeva, Inga

    2012-01-01

    Pētījuma mērķis ir noskaidrot empātijas atšķirības starp improvizācijas teātru, amatierteātru un koru dalībniekiem. Izlasi veido 106 respondenti, no tiem 41 improvizācijas teātru dalībnieks, 34 amatierteātru dalībnieki un 31 koru dalībnieks kā kontroles grupa – respondenti, kuriem tā ir brīvā laika aktivitāte ārpus darba. Dalībnieki ir 14 vīrieši un 92 sievietes vecumā no 18 līdz 30 gadiem, dalībnieku pieredzes ilgums aktiermākslā ir no 1 līdz 15 gadiem. Pētījumā tiek izmantota Saimona Barona...

  11. Nuclear data sheets update for A = 197

    Energy Technology Data Exchange (ETDEWEB)

    Chunmei, Zhou [Chinese Nuclear Data Center, Beijing, BJ (China)

    1996-06-01

    The Nuclear Data Sheet for A = 197 has been carried out on the basis of the nuclear reaction and decay experiments leading to all the nuclei with mass number A = 197 since cutoff date of the last evaluation, December 1989. Most evaluation data have been updated or revised. The nuclei of updated data mainly are {sup 197}Hg, {sup 197}Pb, {sup 197}Bi and {sup 197}Po. The adopted levels and adopted gamma radiations for all nuclei are shown in the tables.

  12. Update of Part 61 impacts analysis methodology

    International Nuclear Information System (INIS)

    Oztunali, O.I.; Roles, G.W.

    1986-01-01

    The US Nuclear Regulatory Commission is expanding the impacts analysis methodology used during the development of the 10 CFR Part 61 rule to allow improved consideration of costs and impacts of disposal of waste that exceeds Class C concentrations. The project includes updating the computer codes that comprise the methodology, reviewing and updating data assumptions on waste streams and disposal technologies, and calculation of costs for small as well as large disposal facilities. This paper outlines work done to date on this project

  13. Update of Part 61 impacts analysis methodology

    International Nuclear Information System (INIS)

    Oztunali, O.I.; Roles, G.W.; US Nuclear Regulatory Commission, Washington, DC 20555)

    1985-01-01

    The US Nuclear Regulatory Commission is expanding the impacts analysis methodology used during the development of the 10 CFR Part 61 regulation to allow improved consideration of costs and impacts of disposal of waste that exceeds Class C concentrations. The project includes updating the computer codes that comprise the methodology, reviewing and updating data assumptions on waste streams and disposal technologies, and calculation of costs for small as well as large disposal facilities. This paper outlines work done to date on this project

  14. Development of the updated system of city underground pipelines based on Visual Studio

    Science.gov (United States)

    Zhang, Jianxiong; Zhu, Yun; Li, Xiangdong

    2009-10-01

    Our city has owned the integrated pipeline network management system with ArcGIS Engine 9.1 as the bottom development platform and with Oracle9i as basic database for storaging data. In this system, ArcGIS SDE9.1 is applied as the spatial data engine, and the system was a synthetic management software developed with Visual Studio visualization procedures development tools. As the pipeline update function of the system has the phenomenon of slower update and even sometimes the data lost, to ensure the underground pipeline data can real-time be updated conveniently and frequently, and the actuality and integrity of the underground pipeline data, we have increased a new update module in the system developed and researched by ourselves. The module has the powerful data update function, and can realize the function of inputting and outputting and rapid update volume of data. The new developed module adopts Visual Studio visualization procedures development tools, and uses access as the basic database to storage data. We can edit the graphics in AutoCAD software, and realize the database update using link between the graphics and the system. Practice shows that the update module has good compatibility with the original system, reliable and high update efficient of the database.

  15. Institutional Ethics Committee Regulations and Current Updates in India.

    Science.gov (United States)

    Mahuli, Amit V; Mahuli, Simpy A; Patil, Shankargouda; Bhandi, Shilpa

    2017-08-01

    The aim of the review is to provide current updates on regulations for ethics committees and researchers in India. Ethical dilemmas in research since time immemorial have been a major concern for researchers worldwide. The question "what makes clinical research ethical" is significant and difficult to answer as multiple factors are involved. The research involving human participants in clinical trials should follow the required rules, regulations, and guidelines in one's own country. It is a dynamic process, and updates have to be learned by researcher and committee members. The review highlights the ethical regulation from the Drug Controller General of India, Clinical Trial Registry of India, and Indian Council of Medical Research guidelines. In this article, the updates on Indian scenario of the Ethical Committee and guidelines are compiled. The review comes handy for clinical researchers and ethics committee members in academic institutions to check on the current updates and keep abreast with the knowledge on regulations of ethics in India.

  16. Internet Journal of Medical Update

    African Journals Online (AJOL)

    admin

    Internet Journal of Medical Update 2010 July;5(2):8-14. Internet Journal ... hospitalizations. This study of Nigerian patients with diabetes examined the adequacy of ..... Physicians need .... relationship between patient education and glycaemic ...

  17. Updated science systems on USCGC Healy

    Science.gov (United States)

    Chayes, D. N.; Roberts, S. D.; Arko, R. A.; Hiller, S. M.

    2008-12-01

    The USCG cutter Healy is the U.S. Arctic research icebreaker. Prior to the 2008 season, a number of upgrades and improvements were made to the science systems. These included the addition of two Bell BGM-3 marine gravity meters. The vessel's existing meterological sensors were enhanced with two RM Young model 85004 heated ultrasonic anemometers; a Paroscientific, Inc. model "MET-3A" air temperature, humidity and barometric pressure subsystem; and an RM Young model 50202 heated rain gauge. The flow through sea water system was updated with new flow meters, a SeaBird SBE45 thermosalinograph, long and a short wave radiation sensors, a Seapoint fluorometer. A Milltech Marine Smart Radio model SR161 Automatic Identification System (AIS) receiver and an updated interface to real-time winch and wire performance have been added. Our onboard real-time GIS has been updated to include real-time plotting of other ship tracks from our AIS receiver and the ability for users to save and share planned tracks. For the HLY0806 leg, we implemented a SWAP ship-to ship wireless connection for our two-ship operations with the Canadian icebreaker Louis S. St. Laurent similar to the one we implemented for our two-ship program with the Swedish icebreaker Oden in 2005. We updated our routine delivery of underway data to investigators, as well as a copy for archiving to the NSF-supported Marine Geoscience Data System (MGDS), using portable "boomerang" drives. An end-user workstation was added to accommodate increasing demand for onboard processing. Technical support for science on the Healy is supported by the U.S. National Science Foundation.

  18. Validación de un modelo empírico para calcular, mediante laser y fotodiodo, la potencia en función de la distancia para un blanco difusor

    OpenAIRE

    Blázquez Campo, Pablo

    2012-01-01

    Este proyecto fin de carrera se centra en un estudio teórico y experimental de un sistema de emisión/recepción, formado por láser y fotodiodo, con el objetivo de validar un modelo empírico que describa el comportamiento de un blanco difusor iluminado con un haz colimado y describa la potencia recibida en función de la distancia con el punto de reflexión. A partir de los resultados experimentales, obtenidos y procesados mediante un software de aplicación general (Matlab) hallaremos la ecuación...

  19. Updating radon daughter bronchial dosimetry

    International Nuclear Information System (INIS)

    Harley, N.H.; Cohen, B.S.

    1990-01-01

    It is of value to update radon daughter bronchial dosimetry as new information becomes available. Measurements have now been performed using hollow casts of the human bronchial tree with a larynx to determine convective or turbulent deposition in the upper airways. These measurements allow a more realistic calculation of bronchial deposition by diffusion. Particle diameters of 0.15 and 0.2 μm were used which correspond to the activity median diameters for radon daughters in both environmental and mining atmospheres. The total model incorporates Yeh/Schum bronchial morphometry, deposition of unattached and attached radon daughters, build up and decay of the daughters and mucociliary clearance. The alpha dose to target cells in the bronchial epithelium is calculated for the updated model and compared with previous calculations of bronchial dose

  20. Evaluation of two updating methods for dissipative models on a real structure

    International Nuclear Information System (INIS)

    Moine, P.; Billet, L.

    1996-01-01

    Finite Element Models are widely used to predict the dynamic behaviour from structures. Frequently, the model does not represent the structure with all be expected accuracy i.e. the measurements realised on the structure differ from the data predicted by the model. It is therefore necessary to update the model. Although many modeling errors come from inadequate representation of the damping phenomena, most of the model updating techniques are up to now restricted to conservative models only. In this paper, we present two updating methods for dissipative models using Eigen mode shapes and Eigen values as behavioural information from the structure. The first method - the modal output error method - compares directly the experimental Eigen vectors and Eigen values to the model Eigen vectors and Eigen values whereas the second method - the error in constitutive relation method - uses an energy error derived from the equilibrium relation. The error function, in both cases, is minimized by a conjugate gradient algorithm and the gradient is calculated analytically. These two methods behave differently which can be evidenced by updating a real structure constituted from a piece of pipe mounted on two viscous elastic suspensions. The updating of the model validates an updating strategy consisting in realizing a preliminary updating with the error in constitutive relation method (a fast to converge but difficult to control method) and then to pursue the updating with the modal output error method (a slow to converge but reliable and easy to control method). Moreover the problems encountered during the updating process and their corresponding solutions are given. (authors)