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Sample records for united defense lp

  1. EXTENSION OF ISOMETRIES BETWEEN THE UNIT SPHERES OF COMPLEX lp(Γ)(p>1) SPACES

    Institute of Scientific and Technical Information of China (English)

    Jijin YI; Ruidong WANG; Xiaoxiao WANG

    2014-01-01

    In this paper, we study the extension of isometries between the unit spheres of complex Banach spaces lp(Γ) and lp(∆)(p > 1). We first derive the representation of isometries between the unit spheres of complex Banach spaces lp(Γ) and lp(∆). Then we arrive at a conclusion that any surjective isometry between the unit spheres of complex Banach spaces lp(Γ)and lp(∆) can be extended to be a linear isometry on the whole space.

  2. $L^p$ Regularity of Some Weighted Bergman Projections on the Unit Disc

    CERN Document Server

    Zeytuncu, Yunus E

    2011-01-01

    We show that weighted Bergman projections, corresponding to weights of the form $M(z)(1-|z|^2)^{\\alpha}$ where $\\alpha>-1$ and $M(z)$ is a radially symmetric, strictly positive and at least $C^2$ function on the unit disc, are $L^p$ regular.

  3. The isometric extension problem in the unit spheres of lp(

    Institute of Scientific and Technical Information of China (English)

    DING; Guanggui(

    2003-01-01

    [1]Tingley, D., Isometries of the unit sphere, Geometriae Dedicata, 1987, 22: 371-378.[2]Ding Guanggui, On the extension of isometries between unit spheres of E and C(Ω), Acta Math. Sinica, New Series, to appear.[3]Ding Guanggui, The 1-Lipschitz mapping between the unit spheres of two Hilbert spaces can be extended to a real linear isometry of the whole space, Science in China, Ser. A, 2002, 45(4): 479-483.[4]Mayer-Nieberg, P., Banach Lattices, Berlin-Heildelberg-NewYork: Springer-Verlag, 1991.[5]Lindenstrauss, J., Tzafriri, L., Classical Banach Spaces Ⅱ, Berlin-Heildelberg-NewYork: Springer-Verlag, 1979.[6]Banach, S., Theoriě des Operations Liněaires, Warszawa: Monografje Matematyczne, 1932.[7]Day, M. M., Normed Linear Spaces, Berlin-Heildelberg-NewYork: Springer-Verlag, 1973.

  4. Metamorphic history of LP/HT migmatites from the Bavarian Unit (Bohemian Massif)

    Science.gov (United States)

    Sorger, Dominik; Hauzenberger, Christoph; Linner, Manfred; Iglseder, Christoph

    2016-04-01

    Granulite facies migmatites are commonly observed in the Bavarian Unit which were formed during a late Variscan (post 330 Ma) LP-HT overprint. This event is related to a delamination of mantle lithosphere and subsequent asthenospheric upwelling. Most of these rocks underwent high degrees of melting forming meta- and diatexites. Former work in the Sauwald area, Upper Austria, by Tropper et al. (2006) determined metamorphic conditions of 700-800°C and 0.4-0.5 Gpa. In this study samples were taken along the (1) Danube valley (west of Linz), from the (2) Lichtenberg area (north of Linz), the (3) Bad Leonfelden area (west of the Rodl Fault) and the (4) Sauwald area (south of the river Danube). Biotite and plagioclase bearing migmatite is very common and occurs all over the investigated area. These rocks are the product of intensive melting (anatexite) and formed at conditions of ~650-700°C and 0.25-0.45 Gpa. Scarce outcrops of garnet bearing Al-rich migmatitic metapelites occur along the Danube valley. The formation of the migmatitc texture with well-developed leucosomes (K-feldspar, plagioclase, quartz) and melanosomes (garnet, cordierite, sillimanite, spinel, ilmenite, ± biotite) indicate high temperature metamorphism. Most of the garnet grains show a homogenous iron-rich composition and form generally an almandine-pyrope (Xalm=0.78-0.80, Xprp=0.16-0.18) solid solution with minor contents of grossular and spessartine (Xgrs=0.028-0.032, Xsps=0.020-0.024). Large garnet porphyroblasts (up to 1cm in size) display a distinct chemical zoning, especially in grossular component. Elevated homogeneous grossular content in the core is followed discontinously by low grossular content at the rim indicating a two stage growth. Garnet core and rim also display different mineral inclusions. Thermobarometric calculations using garnet core compositions with inclusions and garnet rim compositions with matrix phases as well as pseudosection calculations allow the reconstruction of a P

  5. Civil Defense, U. S. A.: A Programmed Orientation to Civil Defense. Unit 1. Civil Defense - Protection Against What?

    Science.gov (United States)

    Defense Civil Preparedness Agency (DOD), Battle Creek, MI.

    An explanation of the need for civil defense in nuclear and natural disasters is presented. A brief historical background of civil defense is given. Major topics include: (1) Types of disasters, (2) Probable objectives of a nuclear attack on the United States, (3) The major defensive measures against a nuclear attack, (4) Some reasons for low…

  6. United States Civil Military Relations: Defense Reform

    Science.gov (United States)

    2016-03-01

    358–421. 154 Lederman, Reorganizing the Joint Chiefs of Staff, 74. 155 Thomas L. McNaugher and Roger L. Sperry , “Improving Military Coordination...edited by Thomas C. Bruneau and Florina Cristiana Matei, 26–38. New York: Routledge Taylor and Francis, 2015. McNaugher, Thomas L. and Roger L... Sperry . “Improving Military Coordination: The Goldwater-Nichols Reorganization of the Department of Defense.” In Who Makes Public Policy: The

  7. Extension of isometries on the unit sphere of l~p (Γ) space

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    In this paper,we obtain that every isometry from the unit sphere S(l p (Γ)) of l p (Γ) (1 < p < ∞,p≠2) onto the unit sphere S(E) of a Banach space E can be extended to be a (real) linear isometry of l p (Γ) onto E,so,we give an affirmative answer to the corresponding Tingley’s problem.

  8. Who Pays for National Defense? Financing Defense Programs in the United States, 1947-2007

    Science.gov (United States)

    Heo, Uk; Bohte, John

    2012-01-01

    Past studies on military expenditures in the United States have primarily focused on the extent to which guns versus butter trade-offs are prevalent without examining this relationship in the context of how other fiscal policy tools are used to pay for defense. Using annual data from 1947-2007, this study examines the relative importance of…

  9. Identifying the influential factors in corrosive processes on the LP shaft of the Elverlingsen E4 turbogenerator set during unit shutdown procedures

    Energy Technology Data Exchange (ETDEWEB)

    Seipp, H.G.; Leidich, F.U. [ALSTOM Power Support GmbH, Mannheim (Germany); Freund, E. [Mark-E AG, Elverlingsen Power Plant (Germany)

    2003-07-01

    Overhauls repeatedly revealed cracks on the grooves of blade suspensions on LP turbine rotors in various turbo-generator sets. Some of these cracks caused costly repairs. Without exception, the starting points of the cracks were identified to be in areas affected by shallow pitting corrosion. In many cases, the same phenomena were found in units which underwent frequent hot and cold start-ups. In order to avoid corrosive attacks on the LP turbine during operational standstills, the shutdown procedures for the unit 4 in Elverlingsen were modified. (orig.) [German] An den Nuten der Schaufelaufhaengungen an ND-Turbinenlaeufern verschiedener Turbogruppen wurden bei Revisionen Risse gefunden, die teilweise aufwaendige Sanierungsmassnahmen zur Folge hatten. Die Rissausgaenge lagen ausnahmslos im Bereich von Muldenkorrosionsangriffen. Besonders haeufig traten diese Phaenomene bei Blockeinheiten mit haeufigen Warm- und Kaltstarts auf. Zur Vermeidung von Korrosionsangriffen an der Niederdruck-Turbine waehrend Betriebsstillstaenden wurde das Abfahren des Blockes 4 im Kraftwerk Elverlingsen modifiziert. (orig.)

  10. LP-80 IMU program status

    Science.gov (United States)

    Jackson, Edward N.

    Development history, system design features, performance, and hardware status are reviewed for the fourth-generation LP-80 strapdown inertial measurement unit (IMU) which is currently in full-scale development to meet the design objectives required for missiles, torpedoes, drones, and range instrumentation system applications. The LP-80 is fully self-contained and operates at all attitudes, providing digital processed outputs of angular rate and linear acceleration measured in the body axis frame. For range applications, the LP-80 is designed to provide linear velocities with respect to a space stabilized coordinate frame.

  11. Inverse spectral results for Schr\\"odinger operators on the unit interval with potentials in L^P spaces

    CERN Document Server

    Amour, Laurent

    2007-01-01

    We consider the Schr\\"odinger operator on $[0,1]$ with potential in $L^1$. We prove that two potentials already known on $[a,1]$ ($a\\in(0,{1/2}]$) and having their difference in $L^p$ are equal if the number of their common eigenvalues is sufficiently large. The result here is to write down explicitly this number in terms of $p$ (and $a$) showing the role of $p$.

  12. Gas Unit and Tract Boundaries, LP and LNG, DNROilGasUnits-Utah Oil and Gas UnitPolygons from the Utah Department of Natural Resources, Oil Gas and Mining Division. http://ogm.utah.gov, Published in 2007, 1:100000 (1in=8333ft) scale, State of Utah Automated Geographic Reference Center.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Gas Unit and Tract Boundaries, LP and LNG dataset, published at 1:100000 (1in=8333ft) scale, was produced all or in part from Other information as of 2007. It...

  13. Civil Defense, U. S. A.: A Programmed Orientation to Civil Defense. Unit 5. Governmental Responsibilities for Civil Defense.

    Science.gov (United States)

    Defense Civil Preparedness Agency (DOD), Battle Creek, MI.

    A description of the laws and orders that provide necessary legal authorization for civil defense activities is provided. In addition, an outline of the responsibilities of all governments and the role of the private sector in civil defense is presented. Topics discussed include: (1) Legal authority for civil defense, (2) Civil defense…

  14. 75 FR 76446 - Waiver of 10 U.S.C. 2534 for Certain Defense Items Produced in the United Kingdom

    Science.gov (United States)

    2010-12-08

    ... United Kingdom AGENCY: Defense Acquisition Regulations System, Department of Defense (DoD). ] ACTION: Notice of waiver of 10 U.S.C. 2534 for certain defense items produced in the United Kingdom. SUMMARY: The....C. 2534 for certain defense items produced in the United Kingdom (UK). 10 U.S.C. 2534 limits...

  15. 78 FR 18876 - Defense Federal Acquisition Regulation Supplement: United States-Korea Free Trade Agreement...

    Science.gov (United States)

    2013-03-28

    ... Regulation Supplement: United States- Korea Free Trade Agreement (DFARS Case 2012-D025) AGENCY: Defense... (DFARS) to implement the United States-Korea Free Trade Agreement. The Republic of Korea is already party..., 2012, to implement the United States-Korea Free Trade Agreement (see the United States-Korea Free Trade...

  16. 75 FR 65460 - Renewal of Department of Defense Federal Advisory Committee; United States Military Academy Board...

    Science.gov (United States)

    2010-10-25

    ... Academy Board of Visitors AGENCY: Department of Defense (DoD). ACTION: Renewal of Federal advisory... Department of Defense gives notice that it is renewing the charter for the United States Military Academy... Academy, including the following: morale and discipline, curriculum, instruction, physical equipment...

  17. Asia-Pacific Missile Defense Cooperation and the United States 2004-2005: A Mixed Bag

    Science.gov (United States)

    2005-02-01

    in cooperating with the United States on various missile defense -related programs. Such close friends and allies as South Korea and Taiwan have made...many local opponents of missile defense argue that the missile threat to Australia is quite low, particularly as North Korea does not yet possess any...2004 in cooperating with the United States. Overall, South Korea does not appear to regard the North Korean missile threat as very likely. Based on

  18. 77 FR 30355 - Defense Federal Acquisition Regulation Supplement: United States-Korea Free Trade Agreement...

    Science.gov (United States)

    2012-05-22

    ... Regulation Supplement: United States- Korea Free Trade Agreement (DFARS Case 2012-D025) AGENCY: Defense... United States-Korea Free Trade Agreement. The Republic of Korea is already party to the World Trade... provisions and clauses in DFARS part 252 to implement the United States-Korea Free Trade Agreement (see the...

  19. On the Lp intersection body

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    In this paper, by using the Brunn-Minkowski-Firey mixed volume theory and dual mixed volume theory, associated with Lp intersection body and dual mixed volume, some dual Brunn-Minkowski inequalities and their isolate forms are established for Lp intersection body about the normalized Lp radial addition and Lp radial linear combination. Some properties of operator Lp are given.

  20. Failure Analysis of Drainage System Under the LP Heater in A 600MW Unit%600MW机组低压加热器疏水系统故障原因浅析

    Institute of Scientific and Technical Information of China (English)

    王波; 吴喜

    2012-01-01

    某600MW机组低压加热器系统由于原设计缺陷,在机组升负荷过程中,其6号低加至7号低加正常疏水逐级自流不畅,使机组冷源损失增大,直接影响了机组热经济性.通过详细分析并加以实验验证,找到了导致低加疏水系统故障的根本原因,提出了技术改造方案以供工程应用参考.%Because the original design of drainage system under the LP heater system in a 600MW unit was defective, it resulted the gravity step by step of the normal drainage from 6 LP heater to 7 LP heater was poor when the unit load was increasing. It increased the cold source loss and directly impacted on the thermal economy of the unit. By careful analysis and experimental verification, the essential reasons leading to drainage system failure had been found and technological transformation programs had been proposed for engineering reference.

  1. Quasi Lp-Intersection Bodies

    Institute of Scientific and Technical Information of China (English)

    Wu Yang YU; Dong Hua WU; Gang Song LENG

    2007-01-01

    The purpose of this paper is to generalize the notion of intersection bodies to that of quasi Lp-intersection bodies. The Lp-analogs of the Busemann intersection inequality and the Brunn Minkowski inequality for the quasi Lp-intersection bodies are obtained. The Aleksandrov-Fenchel inequality for the mixed quasi Lp-intersection bodies is also established.

  2. State Defense Force Monograph Series. Fall 2007, Special Units

    Science.gov (United States)

    2007-01-01

    authors and the visual panorama of artists and film makers. Those World War Two soldiers for whom “taps” has not yet been sounded may still remember the...is a reenactor and living historian, with an emphasis on mounted cavalry, formed and commanded many reenactment units, trained numerous soldiers in

  3. 78 FR 32362 - Implementation of the Defense Trade Cooperation Treaty Between the United States and Australia...

    Science.gov (United States)

    2013-05-30

    ... United States and Australia; Announcement of Effective Date for Regulations ACTION: Final rule... of Australia Concerning Defense Trade Cooperation (referred to herein as ``the Treaty''). DATES... and Australia,'' published on April 11, 2013 (Public Notice 8270, 78 FR 21523) is effective May 16...

  4. 75 FR 65461 - Renewal of Department of Defense Federal Advisory Committee; United States Naval Academy Board of...

    Science.gov (United States)

    2010-10-25

    ... Academy Board of Visitors AGENCY: Department of Defense (DoD). ACTION: Renewal of Federal advisory... Department of Defense gives notice that it is renewing the charter for the United States Naval Academy Board... methods and other matters relating to the United States Naval Academy that the Board decides to consider...

  5. 75 FR 38514 - Application to Export Electric Energy; Brookfield Energy Marketing LP

    Science.gov (United States)

    2010-07-02

    ... Application to Export Electric Energy; Brookfield Energy Marketing LP AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of application. SUMMARY: Brookfield Energy Marketing LP... power marketing agencies and other entities within the United States. The existing...

  6. United States Department of Defense Research in Robotic Unmanned Systems for Combat Casualty Care

    Science.gov (United States)

    2010-01-01

    first responder combat casualty care, and patient evacuation under hostile fire have compounded combat losses throughout history. Force protection of military first responders is complicated by current international and coalition troop deployments for peacekeeping operations, counter terrorism, and humanitarian assistance missions that involve highly visible, politically sensitive low intensity combat in urban terrain. The United States Department of Defense (DoD) has significantly invested in autonomous vehicles, and other robots to support its Future Force. By leveraging

  7. 10 CFR 50.13 - Attacks and destructive acts by enemies of the United States; and defense activities.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Attacks and destructive acts by enemies of the United... destructive acts by enemies of the United States; and defense activities. An applicant for a license to... an enemy of the United States, whether a foreign government or other person, or (b) use or...

  8. Strategic culture and ballistic missile defense: Russia and the United States. Master's thesis

    Energy Technology Data Exchange (ETDEWEB)

    Becker, M.D.

    1993-06-01

    This thesis examines U.S. and Russian history and current policy debates to advance understanding of: (1) the strategic cultures of these nations, particularly with respect to BMD policies in the recent past; and (2) whether and how their strategic cultures and approaches to BMD are changing and how that may affect future strategic BMD developments and the status of the ABM Treaty. The development of BMD strategies, including policies concerning the ABM Treaty, within the framework of the established American and Russian strategic cultures is studied, with due attention to the Soviet experience and legacy in the Russian case. U.S. strategic culture does not seem to have changed significantly with the end of the Cold War, but U.S. BMD priorities have been redefined to reflect a higher priority attached to regional and theater-level defenses. It is apparent that the Soviet experience did have a significant impact on Russian strategic culture. Faced with major changes in its international status, domestic political-military arrangements, and scope of national security concerns, Russian strategic culture is nonetheless moving beyond the old Soviet culture. Future Russian policies regarding the transfer of BMD technology, sharing early warning data, and participating in a global protective system are heavily dependent on domestic political developments. United States, Russia, USSR, Strategic culture, Ballistic missile defense, National strategy, Nuclear strategy, Strategic defense, ABM Treaty, Arms control, Strategic stability.

  9. LP Approach to Statistical Modeling

    OpenAIRE

    Mukhopadhyay, Subhadeep; Parzen, Emanuel

    2014-01-01

    We present an approach to statistical data modeling and exploratory data analysis called `LP Statistical Data Science.' It aims to generalize and unify traditional and novel statistical measures, methods, and exploratory tools. This article outlines fundamental concepts along with real-data examples to illustrate how the `LP Statistical Algorithm' can systematically tackle different varieties of data types, data patterns, and data structures under a coherent theoretical framework. A fundament...

  10. Registration of LP1-2581, LP1-2163H, LP3-1159, and LP640-1304 low phytate spring barley germplasm lines

    Science.gov (United States)

    The Agricultural Research Service, U.S. Dept. of Agriculture (USDA-ARS) has developed and released four low-phytate spring barley (Hordeum vulgare L.) germplasm lines: LP1-2581 (Reg. No._____, PI 658245), LP1-2163H (Reg. No._____, PI 658248 ), LP3-1159 (Reg. No._____, PI 658247), and LP640-1304 (...

  11. ON Lp-MATRICIALLY NORMED SPACES

    Institute of Scientific and Technical Information of China (English)

    Turdebek N. Bekjan

    2005-01-01

    It is proved that there is only one Lp-matricially normed space of dimension 1 and that quotient spaces of Lp-matricially normed spaces are also Lp-matricially normed spaces. Some properties of Lp-matricially normed spaces are given.

  12. 76 FR 9771 - SFPP, L.P.; SFPP, L.P.; SFPP, L.P.; SFPP, L.P.; Notice of Filing

    Science.gov (United States)

    2011-02-22

    ...; OR94-4-021; Docket No. IS06-215-003; Docket No. IS06-220-002] SFPP, L.P.; SFPP, L.P.; SFPP, L.P.; SFPP, L.P.; Notice of Filing Take notice that on February 10, 2011, the SFPP, L.P. filed with the... shippers may be entitled to refunds pursuant to the Commission's orders dated December 8, 2006 (SFPP,...

  13. Joint-Service Integration: An Organizational Culture Study of the United States Department of Defense Voluntary Education System

    Science.gov (United States)

    Benson, Martin K.

    2010-01-01

    The purpose of the descriptive case study with a multiple case framework was to (a) describe the organizational cultures of education programs and leaders in the United States (U.S.) Department of Defense (DoD) voluntary education system on Oahu, Hawaii; (b) determine if an overlapping common organizational culture exists; and (c) assess the…

  14. Symbol RFID Technology to be Deployed at United States Defense Logistics Agency’s Distribution Centers Worldwide

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Symbol Technologies, Inc., The Enterprise Mobility Company, today announced that it had been selected by ODIN technologies, the leader in the physics of RFID testing, software and deployment, to support its recent contract win with the United States Defense Logistics Agency (DLA), the United States Department of Defense’s (DoD) logistics combat support agency that provides supplies and services to America’s military forces worldwide.

  15. Online lektiehjælp

    DEFF Research Database (Denmark)

    Hansen, Jens Jørgen; Remvig, Kirstin

    2016-01-01

    vejledningsdidaktik, herunder metoder, modeller og materialer for lektievejledning i regi af Lektier Online. Lektier Online er en organisation ved Statsbiblioteket i Århus, der tilbyder en online lektiecafe, hvor bl.a. gymnasie-elever kan få hjælp af frivillige universitetsstuderende. Dette didaktiske de-sign er et...

  16. Main: 1LP4 [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available 1LP4 トウモロコシ Corn Zea mays L. Casein Kinase Ii, Alpha Chain Name=Ack2; Zea Mays Mole...DPQLEALVGRHSRKPWLKFMNADNQHLVSPEAIDFLDKLLRYDHQERLTALEAMTHPYFQQVRAAENSRTRA corn_1LP4.jpg ...

  17. Lp (Rn) BOUNDEDNESS FOR THE MARCINKIEWICZ INTEGRAL

    Institute of Scientific and Technical Information of China (English)

    Hu Guoen

    2002-01-01

    Lp (R) boundedness is considered for the higher-dimensional Marcinkiewicz integral which was introduced by Stein. Some conditions implying the Lp (Rn) boundedness for the Marcinkiewicz integral are obtained.

  18. 76 FR 58488 - Dominion Cove Point LNG, LP; Application for Blanket Authorization to Export Previously Imported...

    Science.gov (United States)

    2011-09-21

    ... Dominion Cove Point LNG, LP; Application for Blanket Authorization to Export Previously Imported Liquefied... (Application), filed on August 8, 2011, by Dominion Cove Point LNG, LP (DCP), requesting blanket authorization to export liquefied natural gas (LNG) that previously had been imported into the United States...

  19. 78 FR 14778 - Application to Export Electric Energy; Shell Energy North America (US), L.P.

    Science.gov (United States)

    2013-03-07

    ... Application to Export Electric Energy; Shell Energy North America (US), L.P. AGENCY: Office of Electricity... (US), L.P. (Shell Energy) has applied to renew its authority to transmit electric energy from the..., which authorized Shell Energy to transmit electric energy from the United States to Mexico as a...

  20. 78 FR 14779 - Application to Export Electric Energy; Shell Energy North America (US), L.P.

    Science.gov (United States)

    2013-03-07

    ... Application to Export Electric Energy; Shell Energy North America (US), L.P. AGENCY: Office of Electricity... (US), L.P. (Shell Energy) has applied to renew its authority to transmit electric energy from the..., which authorized Shell Energy to transmit electric energy from the United States to Canada as a...

  1. 78 FR 21523 - Implementation of the Defense Trade Cooperation Treaty Between the United States and Australia

    Science.gov (United States)

    2013-04-11

    ... this regulation to ensure its consistency with the regulatory philosophy and principles set forth in.... (2) The export of any defense article specific to the existence of (e.g., reveals the existence of or...

  2. Equimeasurabily and isometries in noncommutative Lp-spaces

    CERN Document Server

    de la Salle, Mikael

    2007-01-01

    We prove some noncommutative analogues of a theorem by Rudin and Plotkin about equimeasurability and isometries in L_p-spaces. Let 0unital subspaces of noncommutative probability Lp-spaces, the unital completely isometric maps come from *-isomorphisms of the underlying von Neumann algebras. Unfortunately we are only able to treat the case of bounded operators.

  3. Organizational structure and operation of defense/aerospace information centers in the United States of America

    Science.gov (United States)

    Sauter, H. E.; Lushina, L. N.

    1983-01-01

    U.S. Government aerospace and defense information centers are addressed. DTIC and NASA are described in terms of their history, operational authority, information services provided, user community, sources of information collected, efforts under way to improve services, and external agreements regarding the exchange of documents and/or data bases. Contents show how DTIC and NASA provide aerospace/defense information services in support of U.S. research and development efforts. In a general introduction, the importance of scientific and technical information and the need for information centers to acquire, handle, and disseminate it are stressed.

  4. Joint Theater Missile Defense in Taiwan: Protecting United States Interests and Friends

    Science.gov (United States)

    2007-11-02

    people in a disproportionately short period and where the consequences of its release overwhelms local responders. 67 APPENDIX A CHINESE BALLISTIC...2004, Ballistic Missile Defense. Airborne Laser The Airborne Laser (ABL) consists of a high-energy, chemical oxygen iodine laser (COIL) mounted

  5. 76 FR 39411 - Self-Defense of Vessels of the United States

    Science.gov (United States)

    2011-07-06

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOMELAND...-defense against piracy. DATES: This notice is effective on July 6, 2011. ADDRESSES: The policy letter and... States against an act of piracy shall not be liable for monetary damages for any injury or death...

  6. 77 FR 2278 - Waiver for Certain Defense Items Produced in the United Kingdom

    Science.gov (United States)

    2012-01-17

    ... Under Secretary of Defense (Acquisition, Technology, and Logistics) is waiving the statutory limitation... certain items to sources in the national technology and industrial base. The waiver will permit... part of the national technology and industrial base. Subsection (i) of 10 U.S.C. 2534 authorizes...

  7. 78 FR 10610 - Waiver for Certain Defense Items Produced in the United Kingdom

    Science.gov (United States)

    2013-02-14

    ... Under Secretary of Defense (Acquisition, Technology, and Logistics) is waiving the statutory limitation... procurement of certain items to sources in the national technology and industrial base. The waiver will permit... part of the national technology and industrial base. Subsection (i) of 10 U.S.C. 2534 authorizes...

  8. United States Department of Defense: Agency Financial Report Fiscal Year 2014

    Science.gov (United States)

    2014-01-01

    relationships between the USMC and partner nations. Photo by Mass Communication Specialist Seaman Patrick Dionne U.S. Department of Defense Agency...the year, and the relationship between the budgetary resources and the outlays made against them. In accordance with Federal statutes and...102 Note 23 Funds from Dedicated Collections ............................................................. 103 Note 24 Fiduciary

  9. The Impact of Decreased Department of Defense Spending on Employment in the United States

    Science.gov (United States)

    1991-11-01

    Rolling and Drawing 2.4 10.607 Nonferrous Rolling and Drawing, nec 2.3 11.170 New Military Facilities 1.6 00.000 Wood and Radio Cabinets 1.5 16.891...1989.49. Hagstrom. Jerry, and Robert Guskind. "Lobbying the Pentagon." National Jour- nal, 31 May 1986, 1316-21. Henderson, Yolanda K. "Defense

  10. 变频技术在300 MW机组低压加热器疏水泵上的应用%APPLICATION OF FREQUENCY-CONVERTING TECHNOLOGY ON DRAIN PUMP FOR LP HEATER OF A 300MW UNIT

    Institute of Scientific and Technical Information of China (English)

    陈强; 刘建华; 张乐群

    2001-01-01

    The drain system of LP heater was designed as a combined operation system of step-by-step gravity drain and drain pump. When the said pump is operating at constand speed, troublesome problems, shch as higher fault rate, larger pipeline vibration, shorter time for putting LP heater into operation etc, are ubiquitous. Using frequency-converting technology, the water level in LP heater can be controlled by converting the frequency of drain pump’s power supply instead of adjustment with valves. More than one year’s operation of the retrofitted system proved that the operation of said drain pump to be stable, safe and reliable .The rate of putting LP heater into operation reaches 100% and the effect of energy-saving is obvious. The said technology has been rapidly spread in use.%300 MW机组低压加热器疏水系统设计为逐级自流和低压加热器疏水泵联合运行方式,疏水泵定速运行时普遍存在泵故障率高、管道振动大、低压加热器投入率低等问题。利用变频技术将低压加热器水位控制方式由阀门调节改为疏水泵变频控制,改造后一年多运行表明疏水泵运行稳定,安全可靠,低压加热器投入率达100%,节能显著,并很快在湛江发电厂推广使用。

  11. Diffeomorphisms with Lp-Shadowing Property

    Institute of Scientific and Technical Information of China (English)

    Abbas FAKHARI; Keonhee LEE; Khosro TAJBAKHSH

    2011-01-01

    We give a characterization of structurally stable diffeomorphisms by making use of the notion of Lp-shadowing property. More precisely, we prove that the set of structurally stable diffeo morphisms coincides with the C1-interior of the set of diffeomorphisms having Lp-shadowing property.

  12. Radar ambiguity function in Lp frame

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    In modern radar techniques, pulse signal can be replaced by the chirps, which is taken to be signals in Lp space. Wigner's function and ambiguity functions are constructed in an Lp frame and a partial generalization of the uncertainty principle is given by means of the notion of coherent dual.

  13. 77 FR 62601 - United States Department of Energy and United States Department of Defense v. Baltimore & Ohio...

    Science.gov (United States)

    2012-10-15

    ... replies may be submitted either via the Board's e-filing format or in the traditional paper format. Any... traditional paper format should send an original and 10 copies to: Surface Transportation Board, Attn: Docket... current system-average variable unit costs computed under the Board's Uniform Rail Costing System. Movants...

  14. An Illustrative Case Study for Twentieth Century Defense Planners: The Technology and Politics of United States Coastal Defense, 1880-1898.

    Science.gov (United States)

    1980-04-24

    932. 2 lGoodrich, Our New Naval Guns," pp. 667-68. 22"Modern Artillery," p. 296. 36 in the nineteenth century by the crucible or open- hearth methods...comments on coast defense ships. "Seaport Defenses: Proposes Artificial Islands to Protect the Approache to the Harbors." Scientific American 63 (23...August 1890): 112. 157 Particularly interesting: proposed artificial islands similar to fixed concrete battleships to be built in harbors; system

  15. The Petty Projection Inequality for Lp-Mixed Projection Bodies

    Institute of Scientific and Technical Information of China (English)

    Wei Dong WANG; Gang Song LENG

    2007-01-01

    Recently,Lutwak,Yang and Zhang posed the notion of Lp-projection body and established the Lp-analog of the Petty projection inequality.In this paper,the notion of Lp-mixed projection bodyis introduced--the Lp-projection body being a special case.The Petty projection inequality,as well asLutwak's quermassintegrals (Lp-mixed quermassintegrals) extension of the Petty projection inequality,is established for Lp-rnixed projection body.

  16. The New Chapter of the United States-Indonesia Defense Relations: Reengagement through IMET

    Science.gov (United States)

    2013-06-13

    provided by the United States was consistently designed to limit the influence of communism in the country. Therefore, when President Sukarno started to...order to balance the shift taken by President Sukarno . During this period, the Central Intelligence of America (CIA) contributed by supplying weapons...

  17. 76 FR 4706 - Self-Defense of Vessels of the United States

    Science.gov (United States)

    2011-01-26

    ... ``Actions'' column. If you do not have access to the internet, you may view the docket online by visiting... United States against an act of piracy shall not be liable for monetary damages for any injury or death caused by such force to any person engaging in an act of piracy if such force was in accordance...

  18. Promoting Students' Conceptual Understanding of Plant Defense Responses Using the Fighting Plant Learning Unit (FPLU)

    Science.gov (United States)

    Nantawanit, Nantawan; Panijpan, Bhinyo; Ruenwongsa, Pintip

    2012-01-01

    Most students think animals are more interesting than plants as a study topic believing that plants are inferior to animals because they are passive and unable to respond to external challenges, particularly biological invaders such as microorganisms and insect herbivores. The purpose of this study was to develop an inquiry-based learning unit,…

  19. BERGMAN TYPE PROJECTIONS ON Lp SPACES

    Institute of Scientific and Technical Information of China (English)

    Kehe Zhu

    2005-01-01

    The paper is a survey on the action of Bergman type projections on various Lp spaces. The focus is on three types of holomorphic function spaces: weighted Bergman spaces, the Bloch space, and diagonal Besov spaces.

  20. 77 FR 50487 - Application To Export Electric Energy; RBC Energy Services LP

    Science.gov (United States)

    2012-08-21

    ... Application To Export Electric Energy; RBC Energy Services LP AGENCY: Office of Electricity Delivery and... applied to renew its authority to transmit electric energy from the United States to Canada pursuant to... Order No. EA-328 authorizing RBC Energy to transmit electric energy from the United States to Canada...

  1. 77 FR 43589 - Freeport LNG Development, L.P., Freeport LNG Expansion, L.P., FLNG Liquefaction LLC; Supplemental...

    Science.gov (United States)

    2012-07-25

    ... Energy Regulatory Commission Freeport LNG Development, L.P., Freeport LNG Expansion, L.P., FLNG... proposed by Freeport LNG Development, L.P., Freeport LNG Expansion, L.P, and FLNG Liquefaction LLC... existing liquefied natural gas (LNG) import terminal on Quintana Island in Brazoria County, Texas....

  2. 76 FR 53440 - Freeport LNG Development, LP; Freeport LNG Expansion, LP; FLNG Liquefaction LLC; Notice of Intent...

    Science.gov (United States)

    2011-08-26

    ... Energy Regulatory Commission Freeport LNG Development, LP; Freeport LNG Expansion, LP; FLNG Liquefaction... construction and operation of facilities proposed by Freeport LNG Development, LP, Freeport LNG Expansion, LP... liquefied natural gas (LNG) import terminal on Quintana Island in Brazoria County, Texas. The Project...

  3. Lp(a) in hypertensive patients.

    Science.gov (United States)

    Catalano, M; Perilli, E; Carzaniga, G; Colombo, F; Carotta, M; Andreoni, S

    1998-02-01

    Lipoprotein(a) (Lp(a)) is considered an important risk factor for coronary disease, cerebrovascular pathology and re-stenosis of coronary bypass. Few studies have been conducted on this lipoprotein in essential arterial hypertensive patients. The purpose of our study was to measure the serum concentrations of Lp(a) and the main parameters of the lipid profile in a group of essential hypertensive patients not receiving pharmacological treatment and with no clinical signs of associated pathologies or organ damage. A total of 123 Caucasian essential arterial hypertensive patients (47 men and 76 women) were studied and compared with 89 controls (36 men and 53 women) matched in terms of age, sex, body mass index (BMI) and smoking habits. It was found that the hypertensive patients had higher plasma concentrations of Lp(a), total cholesterol (TC), triglycerides (TG) and very low density lipoprotein (VLDL-C) than controls (P < 0.01), with no differences in the plasma concentrations of Lp(a) between the two sexes. Only 10 hypertension patients and seven controls had plasma concentrations of Lp(a) of over 30 mg/dl. Lp(a) does not correlate with the main parameters of the lipid profile. We can confirm that hypertension and dyslipidaemia, which are two of the main risk factors for vascular diseases on an atherosclerotic basis, are often associated. However, higher plasma concentrations of Lp(a), albeit within the normal range, could be an independent risk factor for atherosclerosis, and could contribute towards increasing the incidence of cardiovascular disease in people with essential arterial hypertension.

  4. 75 FR 39680 - Houston Pipe Line Company LP, Worsham-Steed Gas Storage, L.P., Energy Transfer Fuel, LP, Mid...

    Science.gov (United States)

    2010-07-12

    ... Storage, L.P., Energy Transfer Fuel, LP, Mid Continent Market Center, L.L.C., Oasis Pipeline, LP (Not... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-44-000; Docket No. PR10-46-000; Docket No....

  5. Description and utilization of the United States department of defense serum repository: a review of published studies, 1985-2012.

    Directory of Open Access Journals (Sweden)

    Christopher L Perdue

    Full Text Available Specimens in the United States Department of Defense (DoD Serum Repository have accumulated in frozen storage since 1985 when the DoD began universal screening for human immunodeficiency virus. Use of the stored serum for health research has been carefully controlled, but the resulting publications have never been systematically identified or described. The Armed Forces Health Surveillance Center (AFHSC information systems and open (online sites were used as data sources. Through 2012, the repository contained 54,542,658 serum specimens, of which 228,610 (0.42% have been accessed for any purpose. Between 2001 (the first year that comprehensive, digital records were available and 2012, 65.2% of all approved requests for serum were for healthcare or public health investigations, but greater than 99% of all shipped samples were for research. Using two different methods - a structure search of PubMed and an exhaustive online search based on records from AFHSC - we identified 76 articles published between October 1988 and March 2013 that covered a multitude of infectious diseases, injuries, environmental exposures and mental health conditions through analysis of antibodies, biological metabolic, signaling and regulatory substances, Vitamin D, organochlorines, dioxin, omega-3-fatty acid, and portions of human deoxyribonucleic acid. Despite its operational and scientific value, it appears that the DoD Serum Repository has been underutilized. Changes to policy and increased capacity for specimen processing could increase use of the repository without risking privacy or the availability of specimens for the healthcare of individual service members in the future.

  6. Description and Utilization of the United States Department of Defense Serum Repository: A Review of Published Studies, 1985-2012

    Science.gov (United States)

    Perdue, Christopher L.; Cost, Angelia A. Eick; Rubertone, Mark V.; Lindler, Luther E.; Ludwig, Sharon L.

    2015-01-01

    Specimens in the United States Department of Defense (DoD) Serum Repository have accumulated in frozen storage since 1985 when the DoD began universal screening for human immunodeficiency virus. Use of the stored serum for health research has been carefully controlled, but the resulting publications have never been systematically identified or described. The Armed Forces Health Surveillance Center (AFHSC) information systems and open (online) sites were used as data sources. Through 2012, the repository contained 54,542,658 serum specimens, of which 228,610 (0.42%) have been accessed for any purpose. Between 2001 (the first year that comprehensive, digital records were available) and 2012, 65.2% of all approved requests for serum were for healthcare or public health investigations, but greater than 99% of all shipped samples were for research. Using two different methods – a structure search of PubMed and an exhaustive online search based on records from AFHSC – we identified 76 articles published between October 1988 and March 2013 that covered a multitude of infectious diseases, injuries, environmental exposures and mental health conditions through analysis of antibodies, biological metabolic, signaling and regulatory substances, Vitamin D, organochlorines, dioxin, omega-3-fatty acid, and portions of human deoxyribonucleic acid. Despite its operational and scientific value, it appears that the DoD Serum Repository has been underutilized. Changes to policy and increased capacity for specimen processing could increase use of the repository without risking privacy or the availability of specimens for the healthcare of individual service members in the future. PMID:25723497

  7. Assessment of Local, State and Federal Request Processes for Defense Support to Civil Authorities in the United States

    Science.gov (United States)

    2009-12-01

    Emergency Support Function, Military Logistics , Pre-scripted Mission Assignment, Defense Coordination Officer/ Element, USC Title 10/ 32 Forces...Telecommunications Management • Transportation Management It details the logistics functions that will be the focus of the military logistics capabilities

  8. The Impact of Czech Domestic Politics on Missile Defense Agreements Between the United States and the Czech Republic

    Science.gov (United States)

    2009-04-01

    EU membership, although the outspoken leader of the OSD, Vaclav Klaus was loudly critical of many aspects of the EU.23 The Czech leadership after...the parliamentarians required three elections43 and three rounds of balloting before the compromise appointment of ODS founder Vaclav Klaus as...defense6 and in June 2000 suggested to Czech President Vaclav Havel that the Czech Republic offer to host a US missile defense radar.7 Most

  9. Some Inequalities for Lp-mixed Affine Surface Area

    Institute of Scientific and Technical Information of China (English)

    ZHU Xian-yang

    2012-01-01

    In this paper,the concepts of the ith Lp-mixed affine surface area and Lp-polar curvature images are introduced,some new inequalities connecting these new notions with Lp-centroid bodies and p-Blaschke bodies are showed.Moreover,a Blaschke-Santaló type inequality for Lp-mixed affine surface area is established.Our results also imply the similar to the inequalities for Marcus-Lopes,Bergstrom and Ky Fan.

  10. Towards Reengineering the United States Department of Defense: A Financial Case for a Functionally-Aligned, Unified Military Structure

    Science.gov (United States)

    2014-03-01

    he is carrying a grand piano upstairs. (Seib, 1984: np) Despite the arduous challenge, Britain was able to accomplish sweeping defense reform as...measurement techniques for assessing the expected results of reengineering efforts. Organizational Business Process Reengineering BPR...is not unprecedented. The next section highlights tools and techniques that have proven successful in reengineering efforts. These tools and

  11. Implementation of the Defense Business Operations Fund (DBOF) Policies and Unit Costing in the Air Force Institute of Technology (AFIT)

    Science.gov (United States)

    1993-09-01

    a bussines . The "fee for service" program may enable part of the DOD perform better, but other parts of DOD cannot use the program effectively. You...research or class development. What makes AFRT different from MIT, Harvard , or Yale? 3.1. 1 agree. 0 4. In the era of defense drawdown, the DOD may

  12. 77 FR 2293 - AmeriGas Propane, L.P., AmeriGas Propane, Inc., Energy Transfer Partners, L.P., and Energy...

    Science.gov (United States)

    2012-01-17

    ... AmeriGas Propane, L.P., AmeriGas Propane, Inc., Energy Transfer Partners, L.P., and Energy Transfer...'') with AmeriGas Propane, L.P. (``AmeriGas''), AmeriGas Propane, Inc., Energy Transfer Partners, L.P. (``ETP''), and Energy Transfer Partners GP, L.P. (``ETP GP''), which is designed to guard...

  13. Surfing China's National Defense

    Institute of Scientific and Technical Information of China (English)

    Ji Guilin

    2010-01-01

    @@ Following the start of its first test run on August 20, 2009, the website www.mod.gov.cn of the Ministry of National Defense (MOD) of the People's Republic of China has logged more than 2 billion hits,from many countries and regions including China, the United States,the United Kingdom, Japan, Australia and Singapore. China National Defense News reporters recently interviewed Ji Guilin, the website's Editor in Chief, on its performance and the feedback of netizens.

  14. FUV Focus Sweep Exploratory Program for COS at LP4

    Science.gov (United States)

    Sonnentrucker, Paule; Fox, Andrew; Penton, Steve; Oliveira, Cristina; Roman-Duval, Julia; Sahnow, David

    2017-08-01

    As part of the exploratory phase of the move of COS/FUV operations to Lifetime Position 4 (LP4), we designed program 14527 to measure changes in the focus offsets required to optimize spectral resolution at the prospective LP4 position (-5.02" from LP1 in cross-dispersion direction). Following the successful strategy established in program LENA2 (P13635, LP3 move), we executed one focus sweep using the G130M/1222 configuration (FUVB only) and two sweeps using the G130M/1309 configuration (FUVA and FUVB treated separately). The target Feige 48 was observed in this program for a total of 4 external orbits. As previously, we used an auto-correlation method to derive the focus offsets relative to LP3 that maximize spectral resolution at LP4 for the G130M/1309 and G130M/1222 settings. We find that a focus offset value of +40 steps relative to LP3 maximizes spectral resolution at LP4 for the G130M/1309 configuration (FUVA and FUVB combined). For G130M/1222 (FUVB only), the ado! pted focus offset value that maximizes spectral resolution at LP4 is of +142 steps from the relative to LP3. These values were patched into a FSW update to LV0058 on December 17, 2016 (2016.354) and were permanently installed as part of LV0059 on May 8, 2017 (2017.128). This is a partner ISR to 2017-17.

  15. The 600-Pound Gorilla: Why a Smaller Department of Defense Is in the Best Interest of the United States

    Science.gov (United States)

    2012-03-15

    quoted in Nicholas Kerton-Johnson, Justifying America’s Wars: The Conduct and Practice of US Military Intervention (New York, NY: Rutledge , 2011), 3. 19...Secretary of Defense, 2003), 13. 39. Steven M. Kosiak, Cost of the Wars in Iraq and Afghanistan, and Other Military Operations Through 2008 and Beyond...Eastern Instability,” in China’s Rise – Threat or Opportunity?, ed. Herbert S. Yee, 101-123 (New York, NY: Rutledge , 2011), 121. 58. Stephen Glain

  16. 中毒:Lamborghini LP640

    Institute of Scientific and Technical Information of China (English)

    林中鸟; 陈政义(图); 阿邦(图)

    2010-01-01

    这个世纪开始的10年中最漂亮的超级跑车——Murcielago LP640与我肆无忌惮地疯狂了整整一天,我已经沉溺在它的世界,呼吸着那个世界的空气,被那个世界的魅力所同化,它的性格毫无阻隔地渗入了我内脏的四壁。

  17. Compact vs. Exponential-Size LP Relaxations

    Energy Technology Data Exchange (ETDEWEB)

    Carr, R.D.; Lancia, G.

    2000-09-01

    In this paper we introduce by means of examples a new technique for formulating compact (i.e. polynomial-size) LP relaxations in place of exponential-size models requiring separation algorithms. In the same vein as a celebrated theorem by Groetschel, Lovasz and Schrijver, we state the equivalence of compact separation and compact optimization. Among the examples used to illustrate our technique, we introduce a new formulation for the Traveling Salesman Problem, whose relaxation we show equivalent to the subtour elimination relaxation.

  18. Expectation Values and Variance Based on Lp-Norms

    Directory of Open Access Journals (Sweden)

    George Livadiotis

    2012-11-01

    Full Text Available This analysis introduces a generalization of the basic statistical concepts of expectation values and variance for non-Euclidean metrics induced by Lp-norms. The non-Euclidean Lp means are defined by exploiting the fundamental property of minimizing the Lp deviations that compose the Lp variance. These Lp expectation values embody a generic formal scheme of means characterization. Having the p-norm as a free parameter, both the Lp-normed expectation values and their variance are flexible to analyze new phenomena that cannot be described under the notions of classical statistics based on Euclidean norms. The new statistical approach provides insights into regression theory and Statistical Physics. Several illuminating examples are examined.

  19. The Land Processes Distributed Active Archive Center (LP DAAC)

    Science.gov (United States)

    Golon, Danielle K.

    2016-10-03

    The Land Processes Distributed Active Archive Center (LP DAAC) operates as a partnership with the U.S. Geological Survey and is 1 of 12 DAACs within the National Aeronautics and Space Administration (NASA) Earth Observing System Data and Information System (EOSDIS). The LP DAAC ingests, archives, processes, and distributes NASA Earth science remote sensing data. These data are provided to the public at no charge. Data distributed by the LP DAAC provide information about Earth’s surface from daily to yearly intervals and at 15 to 5,600 meter spatial resolution. Data provided by the LP DAAC can be used to study changes in agriculture, vegetation, ecosystems, elevation, and much more. The LP DAAC provides several ways to access, process, and interact with these data. In addition, the LP DAAC is actively archiving new datasets to provide users with a variety of data to study the Earth.

  20. AREA INTEGRAL FUNCTIONS FOR SECTORIAL OPERATORS ON Lp SPACES

    Institute of Scientific and Technical Information of China (English)

    陈泽亁; 孙牧

    2014-01-01

    Area integral functions are introduced for sectorial operators on Lp-spaces. We establish the equivalence between the square and area integral functions for sectorial operators on Lp spaces. This follows that the results of Cowling, Doust, McIntosh, Yagi, and Le Merdy on H∞ functional calculus of sectorial operators on Lp-spaces hold true when the square functions are replaced by the area integral functions.

  1. Flygtninge på langvarig starthjælp

    DEFF Research Database (Denmark)

    Johansen, Adam; Højland, Marianne; Hansen, Henning

    Spørgeskema-, fokusgruppe- og interviewbaseret undersøgelse af personlige og sociale konsekvenser af familiers forsørgelse på starthjælp. Kvalitativ og kvantitativ undersøgelse af starthjælpens konsekvenser for flygtningefamilier med mere end 1 år på starthjælp...

  2. 78 FR 16846 - Notice of Application; Equitrans, L.P.

    Science.gov (United States)

    2013-03-19

    ... Energy Regulatory Commission Notice of Application; Equitrans, L.P. Take notice that on March 1, 2013, Equitrans, L.P. (Equitrans), 625 Liberty Avenue, Suite 1700, Pittsburgh, Pennsylvania 15222, filed in Docket...: 5:00 p.m. Eastern Time on April 2, 2013. Dated: March 12, 2013. Kimberly D. Bose, Secretary....

  3. 76 FR 68745 - Seneca Power Partners, L.P.

    Science.gov (United States)

    2011-11-07

    ...] Seneca Power Partners, L.P. v. New York Independent System Operator, Inc.; Notice of Complaint Take... and Procedures, 18 CFR 385.206, Seneca Power Partners, L.P. (Complainant) filed a complaint against... TTY, call (202) 502-8659. Comment Date: 5 p.m. Eastern Time on November 28, 2011. Dated: October...

  4. 76 FR 50881 - Airworthiness Directives; M7 Aerospace LP Airplanes

    Science.gov (United States)

    2011-08-17

    ...-025-AD; Amendment 39-16771; AD 2011-17-07] RIN 2120-AA64 Airworthiness Directives; M7 Aerospace LP.... SUMMARY: We are adopting a new airworthiness directive (AD) for certain M7 Aerospace LP Models SA226-T... AD, contact M7 Aerospace, LC, 10823 NE. Entrance Road, San Antonio, Texas 78216; telephone (210)...

  5. 78 FR 45592 - DeltaPoint Capital IV, LP;

    Science.gov (United States)

    2013-07-29

    ... ADMINISTRATION DeltaPoint Capital IV, LP; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that DeltaPoint Capital IV, L.P., 45 East Avenue... Business Administration (``SBA'') Rules and Regulations (13 CFR 107.730). DeltaPoint Capital IV,...

  6. Radar ambiguity function in L_p frame

    Institute of Scientific and Technical Information of China (English)

    M.Y.CHI; 齐民友

    2000-01-01

    In modern radar techniques, pulse signal can be replaced by the chirps, which is taken to be signals in Lp space. Wigner’s function and ambiguity functions are constructed in an Lp frame and a partial generalization of the uncertainty principle is given by means of the notion of coherent dual.

  7. 76 FR 63915 - DCP Midstream, LP; Notice of Application

    Science.gov (United States)

    2011-10-14

    ... Energy Regulatory Commission DCP Midstream, LP; Notice of Application Take notice that on September 23, 2011, DCP Midstream, LP (DCP), filed an application pursuant to Section 7(c) of the Natural Gas Act and Part 157 of the Commission's Regulations, for a limited jurisdiction certificate authorizing DCP...

  8. 78 FR 43190 - DCP Midstream, LP; Notice of Application

    Science.gov (United States)

    2013-07-19

    ... Energy Regulatory Commission DCP Midstream, LP; Notice of Application Take notice that on July 1, 2013, DCP Midstream, LP (DCP), filed an application pursuant to Section 7(c) of the Natural Gas Act and Part 157 of the Commission's Regulations, for a limited certificate authorizing DCP to construct...

  9. The role of LP gas in eradicating energy poverty

    Energy Technology Data Exchange (ETDEWEB)

    Kelly, Michael; Behuria, Sarthak

    2010-09-15

    LP Gas is an ideal solution for dealing with energy poverty. Clean burning, low carbon, extremely efficient, requiring minimal infrastructure or R and D investment and with plentiful long term global supply, LP Gas can be quickly introduced to play an important role in eradicating energy poverty and steering both industrialised and developing countries onto more sustainable energy development paths.

  10. 78 FR 21491 - DeltaPoint Capital IV, L.P., DeltaPoint Capital IV (New York), L.P.; Notice Seeking Exemption...

    Science.gov (United States)

    2013-04-10

    ... ADMINISTRATION DeltaPoint Capital IV, L.P., DeltaPoint Capital IV (New York), L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that DeltaPoint Capital IV, L.P. and DeltaPoint Capital IV (New York), L.P., 45 East Avenue, 6th...

  11. Estimated Impacts of Sequestration-Level Funding: United States Department of Defense Fiscal Year 1015 Budget Request

    Science.gov (United States)

    2014-04-01

    3) (7)   Budget Line Items = "CH‐53K (Heavy Lift)" and "CH‐53K RDTE" Amphibious Combat Vehicle ACV ...investments are shown in Figure 4-9. At the PB15 funding level the Marine Corps begins development of the follow-on ACV program to replace the 40-year old...legacy vehicle. At BCA funding, only initial scoping and research efforts could be started. Figure 4-9. ACV Position Units FY 2015 FY 2016 FY

  12. Gas Pipelines, LP and LNG, Published in unknown, DCP Midstream.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Gas Pipelines, LP and LNG dataset, was produced all or in part from Field Survey/GPS information as of unknown. Data by this publisher are often provided in...

  13. LP formulation of asymmetric zero-sum stochastic games

    KAUST Repository

    Li, Lichun

    2014-12-15

    This paper provides an efficient linear programming (LP) formulation of asymmetric two player zero-sum stochastic games with finite horizon. In these stochastic games, only one player is informed of the state at each stage, and the transition law is only controlled by the informed player. Compared with the LP formulation of extensive stochastic games whose size grows polynomially with respect to the size of the state and the size of the uninformed player\\'s actions, our proposed LP formulation has its size to be linear with respect to the size of the state and the size of the uninformed player, and hence greatly reduces the computational complexity. A travelling inspector problem is used to demonstrate the efficiency of the proposed LP formulation.

  14. Estimates of Oseen kernels in weighted $L^{p}$ spaces

    OpenAIRE

    KRAČMAR, Stanislav; Novotný, Antonín; Pokorný, Milan

    2001-01-01

    We study convolutions with Oseen kernels (weakly singular and singular) in both two- and three-dimensional space. We give a detailed weighted $L^{p}$ theory for $ p\\in(1;\\infty$ ] for anisotropic weights.

  15. 王座LAMBORGHINI AVENTADOR LP700-4

    Institute of Scientific and Technical Information of China (English)

    晓天

    2011-01-01

    兰博基尼Murcielago的换代车型Aventador LP 700-4在正式亮相前就已经赚足了关注的眼光,全世界的超跑迷和兰博基尼的工程师一起为Aventador LP 700-4倒计时,现在它终于出现在了我们眼前。

  16. Bending characteristics of dual-hole PM-PCF based on LP01 and LP11 modal interference

    Science.gov (United States)

    Guo, Xuan; Liu, Feng; Gao, Meng-yuan; Tan, Ai-ling; Fu, Xing-hu; Bi, Wei-hong

    2016-03-01

    The bending characteristics of dual-hole polarization maintaining photonic crystal fiber (PM-PCF) are demonstrated in this paper. The modal interference is induced by the LP01 mode and LP11 mode propagating in a single PM-PCF with the same polarization direction. Simulation results demonstrate that the bending radius induces the phase difference between LP01 mode and LP11 mode, which leads to the change of light interference intensity on the fiber output facet. The relationship between bending radius and normalized interference intensity with three different bending angles is discussed, where the bending angle is defined as the angle between hole axis and the x axis. The bending sensitivity is obtained to be about -188.78/m around the bending radius of 1.5 cm with the bending angle of 90°. The bending characteristics can contribute for online bending detection in widespread areas.

  17. H-Distributions: An Extension of H-Measures to an Lp-Lq Setting

    Directory of Open Access Journals (Sweden)

    Nenad Antonić

    2011-01-01

    Full Text Available We use the continuity of Fourier multiplier operators on Lp to introduce the H-distributions—an extension of H-measures in the Lp framework. We apply the H-distributions to obtain an Lp version of the localisation principle and reprove the Murat Lp-Lp′ variant of div-curl lemma.

  18. Determining the group velocity dispersion by field analysis for the LP0X, LP1X, and LP2X mode groups independently of the fiber length: applications to step-index fibers

    DEFF Research Database (Denmark)

    Israelsen, Stine Møller; Usuga Castaneda, Mario A.; Rottwitt, Karsten

    2017-01-01

    By knowing the electric field distribution of a guided mode in an optical fiber, we are able to evaluate the group velocity dispersion in a weakly guiding step-index fiber for a pure mode in the LP0X, LP1X, and LP2X mode groups independently of the fiber length. We demonstrate the method...

  19. Effect of nicotine on melanogenesis and antioxidant status in HEMn-LP melanocytes

    Energy Technology Data Exchange (ETDEWEB)

    Delijewski, Marcin; Beberok, Artur; Otręba, Michał; Wrześniok, Dorota; Rok, Jakub; Buszman, Ewa, E-mail: ebuszman@sum.edu.pl

    2014-10-15

    Nicotine is a natural ingredient of tobacco plants and is responsible for the addictive properties of tobacco. Nowadays nicotine is also commonly used as a form of smoking cessation therapy. It is suggested that nicotine may be accumulated in human tissues containing melanin. This may in turn affect biochemical processes in human cells producing melanin. The aim of this study was to examine the effect of nicotine on melanogenesis and antioxidant status in cultured normal human melanocytes HEMn-LP. Nicotine induced concentration-dependent loss in melanocytes viability. The value of EC{sub 50} was determined to be 7.43 mM. Nicotine inhibited a melanization process in human light pigmented melanocytes and caused alterations of antioxidant defense system. Significant changes in cellular antioxidant enzymes: superoxide dismutase and catalase activities and in hydrogen peroxide content were stated. The obtained results may explain a potential influence of nicotine on biochemical processes in melanocytes in vivo during long term exposition to nicotine. - Graphical abstract: Nicotine inhibits melanogenesis and induces oxidative stress in HEMn-LP melanocytes. - Highlights: • Nicotine induces concentration-dependent loss in melanocytes viability. • Nicotine in non-cytotoxic concentrations inhibits melanogenesis. • Nicotine in higher concentrations induces oxidative stress.

  20. 22 CFR 120.9 - Defense service.

    Science.gov (United States)

    2010-04-01

    ... Defense service. (a) Defense service means: (1) The furnishing of assistance (including training) to foreign persons, whether in the United States or abroad in the design, development, engineering... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Defense service. 120.9 Section 120.9...

  1. Characterization of human high-density lipoprotein subclasses LP A-I and LP A-I/A-II and binding to HepG2 cells

    NARCIS (Netherlands)

    E.P.C. Kilsdonk (Liesbeth); T. van Gent (Teus); A. van Tol (Arie)

    1990-01-01

    markdownabstractAbstract Plasma HDL can be classified according to their apolipoprotein content into at least two types of lipoprotein particles: lipoproteins containing both apo A-I and apo A-II (LP A-I/A-II) and lipoproteins with apo A-I but without apo A-II (LP A-I). LP A-I and LP A-I/A-II

  2. 格值命题逻辑系统LP(X)的闭包算子%Closure Operators of Lattice-valued Propositional Logic LP(X)

    Institute of Scientific and Technical Information of China (English)

    王学芳; 郑逢斌; 徐扬

    2005-01-01

    In this paper, closure operators of lattice-valued propositional logic LP(X) are studied. A family of classical closure operators are defined and the relation between them and closure operators of LP(X) is investigated. At the same time, a tool for checking compactness of LP(X) is given.

  3. Serum Lp(a)levels in patients with liver disease

    Institute of Scientific and Technical Information of China (English)

    Sharanabasappa M; Sudhakar Nayak

    2008-01-01

    Objective:The study was conducted to evaluate the effect of liver diseases on serum Lp(a)levels and also to study the relationship between Lp(a)levels with other lipid parameters and liver function tests in 32 hyperbil-irubinemia patients with total bilirubin >3mg/dL.The results were compared with 20 healthy age matched in-dividuals.Methods:Serum obtained from venous blood sample are used for estimating total cholesterol (TC), triglyceride(TG),high density lipoprotein cholesterol(HDL-c),low density lipoprotein cholesterol(LDL-c), very low density lipoprotein cholesterol(VLDL-c),total protein(TP),albumin(ALB),total bilirubin,direct bilirubin,aspartate amino tranferase(AST),alanine amino transferase(ALT),alkaline phosphatase(ALP), gamma glutamyl transferase (GGT),lipoprotein (a)[Lp(a)],serum phospholipids.Results:There was significant decrease in serum Lp(a)levels in liver disease patients and the decrease was directly correlated with reduced serum albumin levels and inversely with liver function parameters.Conclusion:Thus the present study indicates hepatic synthetic damage has possible biochemical basis for the reduction of serum Lp(a)lev-els.

  4. Lp-PLA(2) as a marker of cardiovascular diseases.

    Science.gov (United States)

    Bhatti, Sabha; Hakeem, Abdul; Cilingiroglu, Mehmet

    2010-03-01

    Inflammation lies at the base of endothelial dysfunction, eventually leading to plaque formation. The degree of inflammation defines the "vulnerability" of plaque to rupture. Numerous strategies have been adopted to identify and eventually treat high-risk vulnerable plaque. Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) has emerged as one such candidate marker of inflammation that may play a direct role in the formation of rupture-prone plaque. Epidemiologic studies have clearly demonstrated the prognostic ability of increased Lp-PLA(2) levels and their association with increased risk of future coronary and cerebrovascular events. Moreover, Lp-PLA(2) might have similar predictive power for both incident coronary heart disease in initially healthy individuals as well as for recurrent events in those with clinically manifest atherosclerosis. The latest evidence has also suggested its incremental value for risk determination over the well-established traditional risk factors and biomarkers in patients with congestive heart failure. These data support an integral role of Lp-PLA(2) activity in lipid peroxidation and cardiovascular risk assessment. This review summarizes the current body of evidence supporting the clinical utility of Lp-PLA(2) and its future applications in cardiovascular medicine.

  5. Lp Estimates of Rough Maximal Functions Along Surfaces with Applications

    Institute of Scientific and Technical Information of China (English)

    Ahmad AL-SALMAN; Abdulla M. JARRAH

    2016-01-01

    In this paper, we study the Lp mapping properties of certain class of maximal oscillatory singular integral operators. We prove a general theorem for a class of maximal functions along surfaces. As a consequence of such theorem, we establish the Lp boundedness of various maximal oscillatory singular integrals provided that their kernels belong to the natural space L log L(Sn−1). Moreover, we highlight some additional results concerning operators with kernels in certain block spaces. The results in this paper substantially improve previously known results.

  6. Dynamically Consistent Nonlinear Evaluations with Their Generating Functions in Lp

    Institute of Scientific and Technical Information of China (English)

    Feng HU

    2013-01-01

    In this paper,we study dynamically consistent nonlinear evaluations in Lp (1 < p < 2).One of our aim is to obtain the following result:under a domination condition,an Ft-consistent evaluation is an ∑g-evaluation in Lp.Furthermore,without the assumption that the generating function g(t,ω,y,z) is continuous with respect to t,we provide some useful characterizations of an εg-evaluation by g and give some applications.These results include and extend some existing results.

  7. Lp CONVERGENCE OF CESARO MEANS ON SPHERE

    Institute of Scientific and Technical Information of China (English)

    Dai Feng; Zhang Xirong

    2000-01-01

    Let Rnbe n-dimensional Euclidean space with n≤3. Denote by Ωn the unit sphere in Rn. For f ∈ L(Ωn) ve denote by σNo (f) its Cesaro means of order δ for spherical harmonic expansions. The special value λ= 2λ n-2 of δ is knowm as the critical one. For 0<δ≤λ, we set P0=2 λ/δ+λ

  8. Defensive Minefield Planning

    Science.gov (United States)

    1989-06-01

    Minefield Planning by Carlos Vallejo Game Lieutenant, Ecuadorian Navy B. S., Escuela Superior Naval, Ecuador 1980 Submitted in partial fulfillment of...was a superior open-ocean naval force to the North Koreans, defensive minewarfare was able to, at least temporarily, defeat U.S. Navy objectives in...Oswaldo Rosero 1 Unit 8 Coastal Route 1 Monterey, California 93940 77 11. Office of the N’aval Attache 4 Direccion de Educacion 2535 15th. st. N. W

  9. Strong asymptotics for Lp extremal polynomials off a complex curve

    Directory of Open Access Journals (Sweden)

    Rabah Khaldi

    2004-01-01

    Full Text Available We study the asymptotic behavior of Lp(σ extremal polynomials with respect to a measure of the form σ=α+γ, where α is a measure concentrated on a rectifiable Jordan curve in the complex plane and γ is a discrete measure concentrated on an infinite number of mass points.

  10. L^p solutions of reflected BSDEs under monotonicity condition

    CERN Document Server

    Rozkosz, Andrzej

    2012-01-01

    We prove existence and uniqueness of L^p solutions of reflected backward stochastic differential equations with p-integrable data and generators satisfying the monotonicity condition. We also show that the solution may be approximated by the penalization method. Our results are new even in the classical case p=2.

  11. On the Configuration-LP for Scheduling on Unrelated Machines

    CERN Document Server

    Verschae, José

    2010-01-01

    One of the most important open problems in machine scheduling is the problem of scheduling a set of jobs on unrelated machines to minimize the makespan. The best known approximation algorithm for this problem guarantees an approximation factor of 2. It is known to be NP-hard to approximate with a better ratio than 3/2. Closing this gap has been open for over 20 years. The best known approximation factors are achieved by LP-based algorithms. The strongest known linear program formulation for the problem is the configuration-LP. We show that the configuration-LP has an integrality gap of 2 even for the special case of unrelated graph balancing, where each job can be assigned to at most two machines. In particular, our result implies that a large family of cuts does not help to diminish the integrality gap of the canonical assignment-LP. Also, we present cases of the problem which can be approximated with a better factor than 2. They constitute valuable insights for constructing an NP-hardness reduction which im...

  12. Lp estimates for-(e)-equation on generalized complex ellipsoids

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    The estimate of a holomorphic supporting function for the generalized complex ellipsoid in is Cn given, This domain is not decoupled. By using this estimate, the best possible Lp estimates for the -(e)-equation and some results of function theory on generalized complex ellipsoids are proved.

  13. Lp-boundedness of flag kernels on homogeneous groups

    CERN Document Server

    Glowacki, Pawel

    2010-01-01

    We prove that the flag kernel singular integral operators of Nagel-Ricci-Stein on a homogeneous group are bounded on the Lp spaces. The gradation associated with the kernels is the natural gradation of the underlying Lie algebra. Our main tools are the Littlewood-Paley theory and a symbolic calculus combined in the spirit of Duoandikoetxea and Rubio de Francia.

  14. View of the LP gas supply/demand in Asia and a survey of the Middle East trend; Asia no LP gas jukyu tenbo to Chuto doko chosa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-09-01

    A study was made on the LP gas supply/demand in Asia including an outlook for 2000. Eleven countries in Asia including NIES countries, ASEAN countries, China and India have been continuing their rapid growth of economy and have rapidly been increasing their energy consumption. There, LP gas spreads as a home use fuel, and countries excluding some LP gas producing countries depend considerably upon the import from the Middle East. The LP gas consumption quantity is steadily increasing in China and India having huge population, etc., and dependence of LP gas is increasing upon LP gas producing countries of the Middle East. Nevertheless, in the Middle East, the domestic consumption of LP gas, mostly butane, is increasing. Namely, butane is used as raw material of MTBE, and LP gas as that of petroleum chemicals. The Middle East has a lot of plant projects of a sizable size in the future, which predicts that LP gas export from LP gas producing countries of the Middle East is decreasing. 2 refs., 62 figs., 57 tabs.

  15. 75 FR 13644 - TORP Terminal LP, Bienville Offshore Energy Terminal Liquefied Natural Gas Deepwater Port License...

    Science.gov (United States)

    2010-03-22

    ... Maritime Administration TORP Terminal LP, Bienville Offshore Energy Terminal Liquefied Natural Gas...) for the TORP Terminal LP, Bienville Offshore Energy Terminal (BOET) Liquefied Natural Gas (LNG... Natural Gas Pipeline, Williams Natural Gas Pipeline, Destin Natural Gas Pipeline, and Viosca...

  16. 75 FR 35017 - Brookfield Energy Marketing LP; Supplemental Notice That Initial Market-Based Rate Filing...

    Science.gov (United States)

    2010-06-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Brookfield Energy Marketing LP; Supplemental Notice That Initial Market... supplemental notice in the above-referenced proceeding of Brookfield Energy Marketing LP's application...

  17. 77 FR 64767 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

    Science.gov (United States)

    2012-10-23

    ... Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Airplanes AGENCY... airworthiness directive (AD) for certain Gulfstream Aerospace LP (Type Certificate previously held by Israel... Certificate previously held by Israel Aircraft Industries, Ltd.) Model Galaxy and Gulfstream 200...

  18. Deregulation of LP gas industry and future problems; LP gas sangyo no kisei kanwa to kongo no kadai

    Energy Technology Data Exchange (ETDEWEB)

    Mori, T.; Okaya, Y.; Kaneko, Y. [The Institute of Energy Economics, Tokyo (Japan)

    1997-01-30

    This paper describes deregulation of LP gas industry and future problems. The conventional regulation in LP gas industry aims at the security of safety of LP gas and the proper business. The deregulation consists of the release of social regulation of safety and the reconsideration based on the introduction of competitive principle. The law was enforced from April, 1997. This law includes the proper response to advancement of safety technology, addition of self-safety incentive, open information to general consumers, and simplification of procedures. Safety and sales are separated through an establishment of safety organization. License system of sales is changed to registration system for easier participation. The current LP gas industry is loosing its competitive force due to its higher cost compared with the competitive fuels. The demand stays in a low level. There are a lot of small-scale retailers, and the enhancement of them is a problem. It is required to improve the productivity by the expansion of scale through cooperation and integration, to reduce the cost by rationalization through bulk supply and centralized monitoring, and to realize the diversification of management.

  19. File list: NoD.Bld.20.AllAg.LP-1 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available NoD.Bld.20.AllAg.LP-1 hg19 No description Blood LP-1 SRX620447,SRX620449,SRX620448,...SRX620446,SRX620445 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/NoD.Bld.20.AllAg.LP-1.bed ...

  20. 75 FR 28485 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

    Science.gov (United States)

    2010-05-21

    ... Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Model Gulfstream 100... adding the following new AD: 2010-11-02 Gulfstream Aerospace LP (Type Certificate Previously Held by... Gulfstream Aerospace LP (Type Certificate previously held by Israel Aircraft Industries, Ltd.)...

  1. LP(K)中RBF神经网络的系统识别问题%LP(K) Approximation Problems in System Identification with RBF Neural Networks

    Institute of Scientific and Technical Information of China (English)

    南东; 隆金玲

    2009-01-01

    Lp approximation problems in system identification with RBF neural networks are investigated.It is proved that by superpositions of some functions of one variable in Lploc(R),one can approximate continuous functionals defined on a compact subset of Lp(K) and continuous operators from a compact subset of Lp1 (K1) to a compact subset of Lp2 (K(2).These results show that if its activation function is in Lploc(R) and is not an even polynomial,then this RBF neural networks can approximate the above systems with any accuracy.

  2. A method for obtaining time-periodic Lp estimates

    Science.gov (United States)

    Kyed, Mads; Sauer, Jonas

    2017-01-01

    We introduce a method for showing a prioriLp estimates for time-periodic, linear, partial differential equations set in a variety of domains such as the whole space, the half space and bounded domains. The method is generic and can be applied to a wide range of problems. We demonstrate it on the heat equation. The main idea is to replace the time axis with a torus in order to reformulate the problem on a locally compact abelian group and to employ Fourier analysis on this group. As a by-product, maximal Lp regularity for the corresponding initial-value problem follows without the notion of R-boundedness. Moreover, we introduce the concept of a time-periodic fundamental solution.

  3. The Limits of Error Correction with lp Decoding

    CERN Document Server

    Wang, Meng; Tang, Ao

    2010-01-01

    An unknown vector f in R^n can be recovered from corrupted measurements y = Af + e where A^(m*n)(m>n) is the coding matrix if the unknown error vector e is sparse. We investigate the relationship of the fraction of errors and the recovering ability of lp-minimization (0 < p <= 1) which returns a vector x minimizing the "lp-norm" of y - Ax. We give sharp thresholds of the fraction of errors that determine the successful recovery of f. If e is an arbitrary unknown vector, the threshold strictly decreases from 0.5 to 0.239 as p increases from 0 to 1. If e has fixed support and fixed signs on the support, the threshold is 2/3 for all p in (0, 1), while the threshold is 1 for l1-minimization.

  4. Lp-PLA₂- a novel risk factor for high-risk coronary and carotid artery disease.

    Science.gov (United States)

    Epps, K C; Wilensky, R L

    2011-01-01

    Lipoprotein-associated phospholipase A2 (Lp-PLA₂) is at the crossroads of lipid metabolism and the inflammatory response. It is produced by inflammatory cells, bound to LDL and other lipoproteins, and once in the arterial wall facilitates hydrolysis of phospholipids. Elevated serum levels of Lp-PLA₂ have been associated with increased cardiovascular risk in healthy populations and in patients with known vascular disease. Here, we review the role of Lp-PLA₂ in the development of atherosclerosis and progression to unstable disease, the utility of Lp-PLA₂ as a risk predictor for coronary and carotid events and the potential clinical benefit of pharmacologic inhibition of Lp-PLA₂.

  5. Dødshjælp, drabsforbud og deontologi

    DEFF Research Database (Denmark)

    Dige, Morten

    2008-01-01

    Et velkendt argument imod aktiv dødshjælp har det deontologiske forbud mod drab eller pligten til ikke at slå ihjel som en central præmis. Sådanne deontologiske argumenter spiller en fremtrædende rolle i nylige publikationer fra Det Etiske Råd. For at gælde ukvalificeret, må disse argumenter imid...

  6. Diffractive beam parameters of LP01 mode of fiber

    Institute of Scientific and Technical Information of China (English)

    Lianhuang Li; Fuyuan Guo

    2009-01-01

    The diffractive beam parameters of LP01 mode of fiber are analyzed in detail. Based on solving linear equations, two formulas for two kinds of mode-field radii as functions of normalized frequency are presented, and relations between angular radius of far-field divergence, beam propagation factor, and normalized frequency are given. Numerical calculation indicates that the maximal relative error is smaller than 1% within a reasonable parameter range.

  7. 兰博基尼 Murcielago LP640

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    兰博基尼跑车的创始人并不喜欢赛车,只是为了和法拉利争一口气而已。如今,狂牛终于有机会尝一尝吐气扬眉的滋味了,最新旗舰LP640比法拉利恩佐要快0.2秒。

  8. LP-VIcode: La Plata Variational Indicators Code

    Science.gov (United States)

    Carpintero, Daniel; Darriba, Luciano; Maffione, Nicolás

    2015-01-01

    LP-VIcode computes variational chaos indicators (CIs) quickly and easily. The following CIs are included: Lyapunov Indicators, also known as Lyapunov Characteristic Exponents, Lyapunov Characteristic Numbers or Finite Time Lyapunov Characteristic Numbers (LIs) Mean Exponential Growth factor of Nearby Orbits (MEGNO) Slope Estimation of the largest Lyapunov Characteristic Exponent (SElLCE) Smaller ALignment Index (SALI) Generalized ALignment Index (GALI) Fast Lyapunov Indicator (FLI) Orthogonal Fast Lyapunov Indicator (OFLI) Spectral Distance (SD) dynamical Spectra of Stretching Numbers (SSNs) Relative Lyapunov Indicator (RLI)

  9. Dødshjælp, drabsforbud og deontologi

    DEFF Research Database (Denmark)

    Dige, Morten

    2008-01-01

    Et velkendt argument imod aktiv dødshjælp har det deontologiske forbud mod drab eller pligten til ikke at slå ihjel som en central præmis. Sådanne deontologiske argumenter spiller en fremtrædende rolle i nylige publikationer fra Det Etiske Råd. For at gælde ukvalificeret, må disse argumenter imid...

  10. ON APPROXIMATION BY REPRODUCING KERNEL SPACES IN WEIGHTED Lp SPACES

    Institute of Scientific and Technical Information of China (English)

    Baohuai SHENG

    2007-01-01

    In this paper, we investigate the order of approximation by reproducing kernel spaces on (-1, 1) in weighted Lp spaces. We first restate the translation network from the view of reproducing kernel spaces and then construct a sequence of approximating operators with the help of Jacobi orthogonal polynomials, with which we establish a kind of Jackson inequality to describe the error estimate.Finally, The results are used to discuss an approximation problem arising from learning theory.

  11. Smell of danger: an analysis of LP-gas odorization

    Energy Technology Data Exchange (ETDEWEB)

    Cain, W.S.; Turk, A.

    1985-03-01

    LP-gas derives warning properties from the odorants ethyl mercaptan or thiophane. Laboratory tests have implied that the average person has the ability to smell the odors before leaking LP-gas reaches one-fifth its lower limit of flammability. Generally, however, laboratory tests ignore or discard persons with a poor sense of smell, especially the elderly and persons with certain types of hyposmia. Some persons who apparently can smell the warning agents when directed may otherwise fail to notice or identify them. Elderly men seem particularly vulnerable to instances of incidental anosmia and olfactory agnosia. Psychophysical testing of the warning agents has been rather unsophisticated. There exists neither a standard protocol for testing nor adequate specification of the perceptual properties that might make one warning agent better than another. Without such developments, improvement in warning agents will fail to occur. Possible improvements include increases in concentration, the use of blends to insure more uniform delivery of agent and, to decrease the perceptual vulnerability of relatively insensitive people, use of agents with favorable psychophysical (stimulus-response) functions and use of agents with favorable adaptation characteristics. Even without a change in existing products, it seems advisable to learn more about the vulnerability of LP-gas users and to employ educational means to reduce risks.

  12. Investigation of UBVRI Light Curves of LP Cephei

    Science.gov (United States)

    Carrigan, B.; Samec, R. G.; McDermith, R. J.

    1995-12-01

    In our study of eccentric eclipsing binary candidates (EEB's), we have obtained UBVRI CCD light curves of the LP Cephei, which was discovered by Wachmann (1972). The observations were taken 21 to 25 September 1994, inclusive, at Kitt Peak National Observatory, Arizona. The CCD photometer system (CCDPHOT) was used in conjunction with the 0.9 m Cassegrain reflector telescope. Five mean precision epochs of minimum light were determined from the observations made during primary and secondary eclipses. A period study has been conducted for all available data Analysis of both Wachmann's timings and our timings yielded the following linear ephemeris: HJD Min I = 2 449 621.732 19(78)d + 0.693 0625(1)XE. Despite the reported displacement of the secondary by Wachmann (1972) , we find that the secondary eclipse occurs at 0.5 phase. We have obtained standard magnitudes and estimated the amount of interstellar extinction for LP Cephei. Reddening Estimates indicate that LP Cephei consists of two B-type Near-Contact components. Simultaneous synthetic light curve solutions are discussed. The system is semidetatched: the secondary component fills its Roche lobe, while the primary component has a fillout of ~ 70 % of its Roche lobe.

  13. Inequalities relating to Lp-version of Petty's conjectured projection inequality

    Institute of Scientific and Technical Information of China (English)

    WANG Wei-dong; LENG Gang-song

    2007-01-01

    Petty's conjectured projection inequality is a famous open problem in the theory of convex bodies. In this paper, it is shown that an inequality relating to Lp-version of the Petty's conjectured projection inequality is developed by using the notions of the Lp-mixed volume and the Lp-dual mixed volume, the relation of the Lp-projection body and the geometric body Γ-pK, the Bourgain-Milman inequality and the Lp-BusemannPetty inequality. In addition, for each origin-symmetric convex body, by applying the Jensen inequality and the monotonicity of the geometric body Γ-pK, the reverses of Lp-version of the Petty's conjectured projection inequality and the Lp-Petty projection inequality are given, respectively.

  14. Antioxidative defense

    Directory of Open Access Journals (Sweden)

    Stevanović Jelka

    2011-01-01

    Full Text Available Free radicals occur constantly during metabolism and take part in numerous physiological processes, such as: intra-cellular and inter-cellular signalization, gene expression, removal of damaged or senescent cells, and control of the tone of blood vessels. However, there is an increased quantity of free radicals in situations of so-called oxidative stress, when they cause serious damage to cellular membranes (peroxidation of their lipids, damage of membrane proteins, and similar, to interior cellular protein molecules, as well as DNA molecules and carbohydrates. This is precisely why the organism has developed numerous mechanisms for removing free radicals and/or preventing their production. Some of these are enzyme-related and include superoxide-dismutase, catalase, glutathione-peroxidase, and others. Other, non-enzyme mechanisms, imply antioxidative activities of vitamins E and C, provitamin A, coenzyme Q, reduced glutation, and others. Since free radicals can leave the cell that has produced them and become dispersed throughout the body, in addition to antioxidative defense that functions within cellular structures, antioxidant extra-cellular defense has also been developed. This is comprised by: transferrin, lactoferrin, haptoglobin, hemopexin, ceruloplasmin, albumins, extra-cellular isoform SOD, extracellular glutathione-peroxidase, glucose, bilirubin, urates, and many other molecules.

  15. 一种基于Cloud-P2P计算模型的恶意代码联合防御网络%Malicious code united-defense network based on Cloud-P2P model

    Institute of Scientific and Technical Information of China (English)

    徐小龙; 吴家兴; 杨庚

    2012-01-01

    The current anti-virus systems are usually unable io respond to endless emerging malicious codes in time. To sohe this problem, this paper proposed and constructed a new malicious code united-defense network based on the Cloud-P2P computing model. The Cloud-P2P model integrated the cloud computing and the P2P computing systems together organically. Servers and user terminals in the malicious code united-defense network carry out their own duties, forming a high-security collaborative defense network against malicious cooes and obtaining the whole group immunity quickly. It also proposed two kinds of hierarchical network topology, C-DHT and D-DHT, which were based on the distributed hash table technology and suitable for the Cloud-P2P computing model. By the introduction of mobile agent technology, realized vaccine agent and patrol agent of the malicious code defense united-network. The malicious code united-defense network based on the Cloud-P2P computing model has ideal performances, such as the network load balance, the rapid response, the comprehensive defense and the good compatibility.%针对目前的反病毒系统在应对恶意代码时通常具有的滞后性,提出并构建了一种新颖的基于CloudP2P计算模型的恶意代码联合防御网络.Cloud-P2P计算模型将云计算与对等计算进行有机融合.恶意代码联合防御网络系统中的集群服务器与用户终端群体联合组成了一个高安全防御网,协同防御恶意代码,并快速产生群体免疫力.为了提高系统的性能表现,提出适用于Cloud-P2P融合计算环境的两种基于分布式哈希表的层次式网络结构C-DHT和D-DHT,并通过引入移动agent技术实现了恶意代码联合防御网络中的疫苗agent和巡警agent.基于Cloud-P2P计算模型的恶意代码联合防御网络具有负载均衡、反应快捷、防御全面和兼容性良好等性能表现.

  16. The Lp_3561 and Lp_3562 Enzymes Support a Functional Divergence Process in the Lipase/Esterase Toolkit from Lactobacillus plantarum

    Science.gov (United States)

    Esteban-Torres, María; Reverón, Inés; Santamaría, Laura; Mancheño, José M.; de las Rivas, Blanca; Muñoz, Rosario

    2016-01-01

    Lactobacillus plantarum species is a good source of esterases since both lipolytic and esterase activities have been described for strains of this species. No fundamental biochemical difference exists among esterases and lipases since both share a common catalytic mechanism. L. plantarum WCFS1 possesses a protein, Lp_3561, which is 44% identical to a previously described lipase, Lp_3562. In contrast to Lp_3562, Lp_3561 was unable to degrade esters possessing a chain length higher than C4 and the triglyceride tributyrin. As in other L. plantarum esterases, the electrostatic potential surface around the active site in Lp_3561 is predicted to be basic, whereas it is essentially neutral in the Lp_3562 lipase. The fact that the genes encoding both proteins were located contiguously in the L. plantarum WCFS1 genome, suggests that they originated by tandem duplication, and therefore are paralogs as new functions have arisen during evolution. The presence of the contiguous lp_3561 and lp_3562 genes was studied among L. plantarum strains. They are located in a 8,903 bp DNA fragment that encodes proteins involved in the catabolism of sialic acid and are predicted to increase bacterial adaptability under certain growth conditions. PMID:27486450

  17. Bivalent rLP2086 (Trumenba®): Development of a well-characterized vaccine through commercialization.

    Science.gov (United States)

    Sunasara, Khurram; Cundy, John; Srinivasan, Sriram; Evans, Brad; Sun, Weiqiang; Cook, Scott; Bortell, Eric; Farley, John; Griffin, Daniel; Bailey Piatchek, Michele; Arch-Douglas, Katherine

    2017-04-19

    The phrase "Process is the Product" is often applied to biologics, including multicomponent vaccines composed of complex components that evade complete characterization. Vaccine production processes must be defined and locked early in the development cycle to ensure consistent quality of the vaccine throughout scale-up, clinical studies, and commercialization. This approach of front-loading the development work helped facilitate the accelerated approval of the Biologic License Application for the well-characterized vaccine bivalent rLP2086 (Trumenba®, Pfizer Inc) in 2014 under Breakthrough Therapy Designation. Bivalent rLP2086 contains two rLP2086 antigens and is licensed for the prevention of meningococcal meningitis disease caused by Neisseria meningitidis serogroup B in individuals 10-25years of age in the United States. This paper discusses the development of the manufacturing process of the two antigens for the purpose of making it amenable to any manufacturing facility. For the journey to commercialization, the operating model used to manage this highly accelerated program led to a framework that ensured "right the first time" execution, robust process characterization, and proactive process monitoring. This framework enabled quick problem identification and proactive resolutions, resulting in a robust control strategy for the commercial process. Copyright © 2017. Published by Elsevier Ltd.

  18. The Precious Sortie: The United States Air Force at the Intersection of Rising Energy Prices, an Aging Fleet, a Struggling Recapitalization Effort, and Stressed Defense Budgets

    Science.gov (United States)

    2009-03-01

    Respondents should be aware that notwithstanding any other provision of law , no person shall be subject to a penalty for failing to comply with a collection...them at their own peril. 26 NOTES 1 Gayle Putrich and Vago Muridan, "Rising Oil Prices Change USAF Ops," DefenseNews, July 14, 200S, http...accessed July 30, 200S). 4 Vago Muridan, "Oil Prices Reshape How the Air Force Flies," AirForceTimes, July 14, 200S,_ http://www.airforcetimes.com

  19. Technical Soddi Defenses: The Trojan Horse Defense Revisited

    Directory of Open Access Journals (Sweden)

    Chad Steel

    2014-12-01

    Full Text Available In 2004, the Trojan horse defense was at a crossroads, with two child pornography cases where it was successfully employed in the United Kingdom, resulting in acquittals.  The original Trojan horse defense has now become part of the more general “technical SODDI” defense, which includes the possibility of unknown actors using unsecured Wi-Fi connections or having physical access to a computer to perform criminal acts.  In the past ten years, it has failed to be effective in the United States for criminal cases, with no published acquittals in cases where it was the primary defense.  In the criminal cases where it has been used as leverage in plea negotiations, there has been either poor forensics performed by the prosecution or political pressure to resolve a matter.  On the civil side, however, the defense has been wildly successful, effectively shutting down large John Doe copyright infringement litigation against non-commercial violators.  

  20. Defense Acquisition Performance Assessment Report

    Science.gov (United States)

    2006-01-01

    Incorporated – “Changing the System” HeLLeR , TRiCiA A., Deputy Director of Congressional Support, Technical and Analytical Support, USAF A-Team...Interview Recorder” HeLLieR, RiCHARD, Director of Air Force Programs, United Technologies – “Joint Stars System” HeRMAN , DR. ROBeRT, Member, Defense

  1. Chaos detection tools: The LP-VIcode and its applications

    Science.gov (United States)

    Darriba, L. A.; Maffione, N. P.; Cincotta, P. M.; Giordano, C. M.

    A very important topic in galactic dynamics is the detection of instabilities of a given system and the possible appearance of chaos. Such a chaotic bahaviour can be detected and studied by means of variational chaos in- dicators (CIs). The CIs are based on the study of the evolution of initial deviation vectors, which makes these techniques specially sensitive to in- dicate the presence of chaos. Notwithstanding their special sensitiveness to identify chaos, the CIs are still good alternatives to determine also the resonance web. On the other hand, the so-called spectral analysis methods are based on the study of some quantity (e.g. the frequency) on a single orbit, which turns these techniques very efficient for the determination of the resonant struc- ture of the system. The analysis of the interaction among chaotic and regular components as well as the determination of the resonant structure of the Hamiltonian leads to a deeper understanding of the system's dynamics. Despite the advan- tages of the simultaneous application of both types of techniques, many researchers keep applying only one of them. Herein, we present an alpha version of a program coded in Fortran, the LP-VIcode. Although the code is in a developing stage, it can compute several CIs, and here we apply it together with the Frequency Modified Fourier Transform (FMFT) (Sidlichovský & Nesvorný 1996) to study the stationary space (Schwarzchild 1993) of an average realistic Hamiltonian model (Muzzio et al. 2005). Using the LP-VIcode, in Maffione et al. (2011b) and Darriba et al. (sub- mitted) the authors suggest an efficient package of CIs to study a general Hamiltonian. Here the research is extended to show that the complemen- tary use of the LP-VIcode and the spectral analysis methods is highly rec- ommended to study a realistic Hamiltonian model.

  2. Biharmonic eigen-value problems and Lp estimates

    Directory of Open Access Journals (Sweden)

    Chaitan P. Gupta

    1990-01-01

    Full Text Available Biharmonic eigen-values arise in the study of static equilibrium of an elastic body which has been suitably secured at the boundary. This paper is concerned mainly with the existence of and Lp-estimates for the solutions of certain biharmonic boundary value problems which are related to the first eigen-values of the associated biharmonic operators. The methods used in this paper consist of the “a-priori” estimates due to Agmon-Douglas-Nirenberg and P. L. Lions along with the Fredholm theory for compact operators.

  3. Defense Meteorological Satellite Program (DMSP) Film

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The United States Air Force Defense Meteorological Satellite Program (DMSP) Operational Linescan System (OLS) is a polar orbiting meteorological sensor with two...

  4. Surfing China’s National Defense

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Following the start of its first test run on August 20, 2009, the website www.mod.gov.cn of the Ministry of National Defense (MOD) of the People’s Republic of China has logged more than 2 billion hits, from many countries and regions including China, the United States, the United Kingdom, Japan, Australia and Singapore. China National Defense News reporters recently interviewed Ji Guilin, the website’s Editor in Chief, on its performance and the feedback of netizens.

  5. 兰博基尼LP640为极速代言

    Institute of Scientific and Technical Information of China (English)

    刘畅

    2007-01-01

    @@ 兰博基尼公司在双门超级跑车Murcielago LP 640的基础上再度投入热情,结果就是LP640 Roadster的诞生.LP 640表示其发动机的重要指标,L代表纵置,P表示后置,640代表最大功率为640马力,Roadster则表示它是一款敞篷车.

  6. THE HOMOGENEOUS DIRICHLET PROBLEM FOR QUASILINEAR ANISOTROPIC DEGENERATE PARABOLIC-HYPERBOLIC EQUATION WITH Lp INITIAL VALUE

    Institute of Scientific and Technical Information of China (English)

    Wang Zhigang; Li Yachun

    2012-01-01

    The aim of this paper is to prove the well-posedness (existence and uniqueness)of the Lp entropy solution to the homogeneous Dirichlet problems for the anisotropic degenerate parabolic-hyperbolic equations with Lp initial value.We use the device of doubling variables and some technical analysis to prove the uniqueness result.Moreover we can prove that the Lp entropy solution can be obtained as the limit of solutions of the corresponding regularized equations of nondegenerate parabolic type.

  7. Training Lp norm multiple kernel learning in the primal.

    Science.gov (United States)

    Liang, Zhizheng; Xia, Shixiong; Zhou, Yong; Zhang, Lei

    2013-10-01

    Some multiple kernel learning (MKL) models are usually solved by utilizing the alternating optimization method where one alternately solves SVMs in the dual and updates kernel weights. Since the dual and primal optimization can achieve the same aim, it is valuable in exploring how to perform Lp norm MKL in the primal. In this paper, we propose an Lp norm multiple kernel learning algorithm in the primal where we resort to the alternating optimization method: one cycle for solving SVMs in the primal by using the preconditioned conjugate gradient method and other cycle for learning the kernel weights. It is interesting to note that the kernel weights in our method can obtain analytical solutions. Most importantly, the proposed method is well suited for the manifold regularization framework in the primal since solving LapSVMs in the primal is much more effective than solving LapSVMs in the dual. In addition, we also carry out theoretical analysis for multiple kernel learning in the primal in terms of the empirical Rademacher complexity. It is found that optimizing the empirical Rademacher complexity may obtain a type of kernel weights. The experiments on some datasets are carried out to demonstrate the feasibility and effectiveness of the proposed method.

  8. Management development for the LP-gas dealer

    Energy Technology Data Exchange (ETDEWEB)

    1976-09-01

    The Iowa LP-Gas Association and Iowa State University offer suggestions to help LP-gas dealers improve their management skills. Management must realize that although it can purchase machines and material and standardize methods, it cannot buy the will to work. The often-neglected human factor always proves to be the most important single factor. Research findings in employee motivation include (1) the ability of the supervisor to differentiate his role and functions from those performed by the people he supervises, (2) the supervisor's ability to delegate, (3) employee-centeredness vs. production-centeredness, and (4) group pride. The good supervisor can effectively motivate his employees through recognition as an individual, job security, freedom from arbitrary action, opportunity to advance, meaningful tasks, congenial associates, satisfactory working conditions, fair wages, competent leadership, and employee voice in matters concerning him and his job. Effective management depends on the flow of horizontal and vertical communication. All too often, however, less than complete communications threaten profitability and job efficiency. Supervisors should also learn how to avoid barriers to understanding, how to communicate a new idea, and how to give orders.

  9. MULTIPLIERS AND TENSOR PRODUCTS OF L(p, q) LORENTZ SPACES

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Let G be a locally compact abelian group. The main purpose of this article is to find the space of multipliers from the Lorentz space L(p1, q1)(G) to L(p'2, q'2)(G). For this reason, the authors define the spaceAp2,q2p1,q1(G), discuss its properties and prove that the space of multipliers from L(p1, q1)(G) to L(p'2, q'2)(G) is isometrically isomorphic to the dual of Ap2,q2p1,q1(G).

  10. Extremum of geometric functionals involving general L p $L_{p}$ -projection bodies

    Directory of Open Access Journals (Sweden)

    Weidong Wang

    2016-05-01

    Full Text Available Abstract Following the discovery of general L p $L_{p}$ -projection bodies by Ludwig, Haberl and Schuster determined the extremum of the volume of the polars of this family of L p $L_{p}$ -projection bodies. In this paper, the result of Haberl and Schuster is extended to all dual quermassintegrals, and a dual counterpart for the quermassintegrals of general L p $L_{p}$ -projection bodies is also obtained. Moreover, the extremum of the L q $L_{q}$ -dual affine surface areas of polars of general L p $L_{p}$ -projection bodies are determined.

  11. Design and Synthesis of Novel Pyrazole-based Lp-PLA2 Inhibitors%Design and Synthesis of Novel Pyrazole-based Lp-PLA2 Inhibitors

    Institute of Scientific and Technical Information of China (English)

    王毅; 徐为人; 邵华; 谢亚非; 王建武

    2011-01-01

    A series of novel pyrazole-based lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitors have been de- signed and synthetized by a variety of acetophenones via a 10-step convergent approach. The synthetic approach is carefully optimized, and an unsuccessful alternative route is also discussed. The in vitro biological activity reveals that all the synthesized compounds are potent Lp-PLA2 inhibitors with compound 13b being the most potent one (Lp-PLA2, IC50= 1.5 nmol/L).

  12. A novel putative lipoprotein receptor (CasLpR) in the hemocytes of the blue crab, Callinectes sapidus: cloning and up-regulated expression after the injection of LPS and LTA.

    Science.gov (United States)

    Tsutsui, Naoaki; Chung, J Sook

    2012-03-01

    The full-length cDNA encoding a putative lipoprotein receptor (CasLpR) was isolated from the hemocytes of Callinectes sapidus using 5' and 3' RACEs. The open reading frame for CasLpR contains a precursor of putative CasLpR consisting of 1710 amino acid residues including 22 amino acid residues of the signal peptide (22 amino acids). Mature CasLpR (1688 amino acids with 5.6% of phosphorylation sites) has multiple, putative functional domains: five low-density lipoprotein receptor domains in the N-terminus, and a G-protein-coupled receptor proteolysis site domain and a 7 transmembrane receptor (secretin family) domain in the C-terminus. To date, there are no proteins with a similar domain structure in the GenBank. The expression pattern of CasLpR was exclusive in hemocytes among all tested tissues obtained from a juvenile female at intermolt stage: brain, eyestalk ganglia, pericardial organs, and thoracic ganglia complex (nervous system); hepatopancreas (digestive system); heart, artery and hemocytes (circulatory system); gill and antennal gland (excretory system), hypodermis; and Y-organ (endocrine organ). There was no CasLpR expression in the ovary of an adult female. A putative function of CasLpR was examined after challenges of lipopolysaccharides (LPS) and lipoteichoic acid (LTA) in vivo using qRT-PCR assays. Animals at 24 h after injection of LPS or LTA up-regulated the expression of CasLpR in hemocytes by ∼3.5 and 1.4 folds, respectively, compared to the controls that received saline injection. LPS challenge also caused the greatest increment (∼55 folds) of heat shock protein 90 (Hsp90) expression in these samples. These data indicate that putative CasLpR and CasHsp90 may be involved in the defense system or the stress response of C. sapidus. Copyright © 2011 Elsevier Ltd. All rights reserved.

  13. Lubrication of OLA/TEA/LP/H2O System%OLA/TEA/LP/H2O体系的润滑性

    Institute of Scientific and Technical Information of China (English)

    陈素萍; 陆梅青; 施翔

    2005-01-01

    以OLA/TEA/LP/H2O体系为润滑剂,测定了其在铝合金表面的磨痕宽度和摩擦系数.同时与液体石蜡和商用润滑剂进行了比较,结果表明,OLA/TEA/LP/H2O体系对于铝合金材料是一种较好的润滑剂.

  14. Infimal Convolution Regularisation Functionals of BV and Lp Spaces

    KAUST Repository

    Burger, Martin

    2016-02-03

    We study a general class of infimal convolution type regularisation functionals suitable for applications in image processing. These functionals incorporate a combination of the total variation seminorm and Lp norms. A unified well-posedness analysis is presented and a detailed study of the one-dimensional model is performed, by computing exact solutions for the corresponding denoising problem and the case p=2. Furthermore, the dependency of the regularisation properties of this infimal convolution approach to the choice of p is studied. It turns out that in the case p=2 this regulariser is equivalent to the Huber-type variant of total variation regularisation. We provide numerical examples for image decomposition as well as for image denoising. We show that our model is capable of eliminating the staircasing effect, a well-known disadvantage of total variation regularisation. Moreover as p increases we obtain almost piecewise affine reconstructions, leading also to a better preservation of hat-like structures.

  15. An Examination of the Role of the United States Army Reserve in Support of the Defense Support of Civil Authorities (DSCA)

    Science.gov (United States)

    2014-06-13

    law when events preclude law through judicial proceedings; and suppress insurrection, domestic violence, or conspiracy to 64 protect the...of an organization. However, to note, Army Reserve units typically concentrate on training during these periods, and external distractors are limited

  16. 77 FR 68116 - TEAK Texana Transmission Company, LP; Notice of Petition for Rate Approval

    Science.gov (United States)

    2012-11-15

    ... Energy Regulatory Commission TEAK Texana Transmission Company, LP; Notice of Petition for Rate Approval Take notice that on November 2, 2012, TEAK Texana Transmission Company, LP (TEAK) filed a Petition for Rate Approval pursuant to 284.123(b)(2) of the Commissions regulations for firm and...

  17. 77 FR 68118 - TexStar Transmission, LP; Notice of Petition for Rate Approval

    Science.gov (United States)

    2012-11-15

    ... Federal Energy Regulatory Commission TexStar Transmission, LP; Notice of Petition for Rate Approval Take notice that on November 2, 2012, TexStar Transmission, LP (TexStar) filed a Petition for Rate Approval... transportation services, as more fully detailed in the petition. Any person desiring to participate in this...

  18. 77 FR 21764 - Shell Pipeline Company LP; Notice of Petition for Declaratory Order

    Science.gov (United States)

    2012-04-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Shell Pipeline Company LP; Notice of Petition for Declaratory Order Take notice that on March 30, 2012, pursuant to Rule 207(a)(2), Shell Pipeline Company LP (SPLC) submitted...

  19. 78 FR 71601 - Shell Pipeline Company LP; Notice of Petition for Declaratory Order

    Science.gov (United States)

    2013-11-29

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Shell Pipeline Company LP; Notice of Petition for Declaratory Order Take... Procedure, 18 CFR 385.207(a)(2)(2013), Shell Pipeline Company LP (SPLC) filed a petition requesting...

  20. 76 FR 40723 - Dominion Cove Point LNG, LP; Notice of Technical Conference

    Science.gov (United States)

    2011-07-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Dominion Cove Point LNG, LP; Notice of Technical Conference On May 27, 2011, pursuant to section 4 of the Natural Gas Act (NGA), Dominion Cove Point LNG, LP (Cove Point) filed...

  1. 78 FR 35263 - Freeport LNG Development, L.P.; Application for Blanket Authorization To Export Previously...

    Science.gov (United States)

    2013-06-12

    ... Freeport LNG Development, L.P.; Application for Blanket Authorization To Export Previously Imported... receipt of an application (Application), filed on April 19, 2013, by Freeport LNG Development, L.P. (Freeport LNG), requesting blanket authorization to export liquefied natural gas (LNG) that previously...

  2. 76 FR 81925 - Freeport LNG Development, L.P.; Notice of Application

    Science.gov (United States)

    2011-12-29

    ... Energy Regulatory Commission Freeport LNG Development, L.P.; Notice of Application Take notice that on December 9, 2011, Freeport LNG Development, L.P. (Freeport LNG), filed an application pursuant to Section 3... authorization to modify the certificated LNG facilities located on Quintana Island, Texas. The filing may...

  3. 75 FR 74029 - Sabine Pass LNG, L.P.; Notice of Application

    Science.gov (United States)

    2010-11-30

    ... Energy Regulatory Commission Sabine Pass LNG, L.P.; Notice of Application November 22, 2010. Take notice that on November 12, 2010, Sabine Pass LNG, L.P. (Sabine Pass), 700 Milam Street, Suite 800, Houston... a redundant high pressure boil off gas compressor at its existing Sabine Pass LNG Terminal,...

  4. On the boundedness of operators in LP(ιq and Triebel-Lizorkin Spaces

    Directory of Open Access Journals (Sweden)

    João Pedro Boto

    2008-01-01

    Full Text Available Given a bounded linear operator T:LPO(ℝn→Lp1(ℝn, we state conditions under which T defines a bounded operator between corresponding pairs of Lp(ℝn;ιq spaces and Triebel-Lizorkin spaces Fp,qs(ℝn. Applications are given to linear parabolic equations and to Schrödinger semigroups.

  5. 76 FR 63918 - Tesoro Refining and Marketing Company v. SFPP, L.P.; Notice of Complaint

    Science.gov (United States)

    2011-10-14

    ... Energy Regulatory Commission Tesoro Refining and Marketing Company v. SFPP, L.P.; Notice of Complaint.... 13(1), Tesoro Refining and Marketing Company (Complainant) filed a formal complaint against SFPP L.P...., Washington, DC 20426. This filing is accessible on-line at http://www.ferc.gov , using the ``eLibrary'' link...

  6. 77 FR 28375 - Eagle Rock Desoto Pipeline, L.P.; Notice of Petition for Rate Approval

    Science.gov (United States)

    2012-05-14

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Eagle Rock Desoto Pipeline, L.P.; Notice of Petition for Rate Approval Take notice that on May 1, 2012, Eagle Rock Desoto Pipeline, L.P. (Desoto) filed a Rate Election pursuant...

  7. 77 FR 74182 - Magic Valley Pipeline, L.P.; Notice of Petition for Rate Approval

    Science.gov (United States)

    2012-12-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Magic Valley Pipeline, L.P.; Notice of Petition for Rate Approval Take notice that on November 30, 2012, Magic Valley Pipeline, L.P. (Magic Valley) filed a petition for rate...

  8. 77 FR 70432 - Magic Valley Pipeline, L.P.; Notice of Filing

    Science.gov (United States)

    2012-11-26

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Magic Valley Pipeline, L.P.; Notice of Filing Take notice that on November 15, 2012, Magic Valley Pipeline, L.P. (Magic Valley) filed to revise its Statement of Operating...

  9. 78 FR 11965 - Agency Information Collection (Learner's Perception (LP) Survey) Activities Under OMB Review

    Science.gov (United States)

    2013-02-20

    ... AFFAIRS Agency Information Collection (Learner's Perception (LP) Survey) Activities Under OMB Review...'s Perception (LP) Survey, VA Form 10-0439. OMB Control Number: 2900-0691. Type of Review: Extension... trainees perception of their clinical experience with VA versus non-VA facilities. VA will use the data...

  10. 77 FR 74280 - Proposed Information Collection (Learner's Perception (LP) Survey); Comment Request

    Science.gov (United States)

    2012-12-13

    ... AFFAIRS Proposed Information Collection (Learner's Perception (LP) Survey); Comment Request AGENCY.... Title: Learner's Perception (LP) Survey, VA Form 10-0439. OMB Control Number: 2900-0691. Type of Review... trainees perception of their clinical experience with VA versus non-VA facilities. VA will use the data...

  11. 78 FR 13661 - Energy Transfer Fuel, LP; Notice of Petition for Rate Approval

    Science.gov (United States)

    2013-02-28

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Energy Transfer Fuel, LP; Notice of Petition for Rate Approval Take notice that on February 15, 2013, Energy Transfer Fuel, LP filed for approval of rates for...

  12. 76 FR 41432 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

    Science.gov (United States)

    2011-07-14

    ... Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Model Galaxy, Gulfstream... AD. Discussion The Civil Aviation Authority (CAA), which is the aviation authority for Israel, has...: Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.): Docket No...

  13. 76 FR 44055 - BAC Home Loans Servicing, LP, et al.; Notice of Application and Temporary Order

    Science.gov (United States)

    2011-07-22

    ... COMMISSION BAC Home Loans Servicing, LP, et al.; Notice of Application and Temporary Order July 18, 2011... Act, with respect to an injunction entered against BAC Home Loans Servicing, LP (``HLS'') on May 31... (``BAC''). HLS is an entity that services mortgage loans and provides mortgage services,...

  14. 76 FR 12103 - Erie Boulevard Hydropower, L.P; Notice of Settlement Agreement and Soliciting Comments

    Science.gov (United States)

    2011-03-04

    ... Energy Regulatory Commission Erie Boulevard Hydropower, L.P; Notice of Settlement Agreement and.... Date Filed: February 18, 2011. d. Applicant: Erie Boulevard Hydropower, L.P. e. Location: The existing... Daoust, Erie Boulevard Hydropower, 33 West 1st Street, South, Fulton, NY, 13069; (315) 598-6131. i. FERC...

  15. The Syntax of Lattice-Valued Propositional Logic System lp(X)

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Lattice-valued logic plays an important role in multi-valued logic systems. A lattice valued logic system lp(X) is constructed. The syntax of lp(X) is discussed. It may be more convenient in application and study especially in the case that the valuation domain is finite lattice implication algebra.

  16. 77 FR 3762 - Magellan Pipeline Company, L.P.; Notice of Petition for Declaratory Order

    Science.gov (United States)

    2012-01-25

    ... Energy Regulatory Commission Magellan Pipeline Company, L.P.; Notice of Petition for Declaratory Order... Commission's (Commission) Rules of Practice and Procedure, 18 CFR 385.207(a)(2)(2011), Magellan Pipeline Company, L.P. (Magellan) filed a petition for a declaratory order that approves priority committed...

  17. 75 FR 36296 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

    Science.gov (United States)

    2010-06-25

    ... Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd... Previously Held by Israel Aircraft Industries, Ltd.): Docket No. FAA-2010-0555; Directorate Identifier 2010.... Applicability (c) This AD applies to Gulfstream Aerospace LP (Type Certificate previously held by...

  18. 77 FR 32069 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

    Science.gov (United States)

    2012-05-31

    ... Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Airplanes AGENCY... previously held by Israel Aircraft Industries, Ltd.) Model Galaxy and Gulfstream 200 airplanes. This proposed.... 39.13 by adding the following new AD: Gulfstream Aerospace LP (Type Certificate previously held...

  19. 78 FR 47546 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

    Science.gov (United States)

    2013-08-06

    ... Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Airplanes AGENCY... Certificate Previously Held by Israel Aircraft Industries, Ltd.) Model Gulfstream 100 airplanes, and Model...: 2013-14-10 Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries,...

  20. 78 FR 11567 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

    Science.gov (United States)

    2013-02-19

    ... Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Airplanes AGENCY... Previously Held by Israel Aircraft Industries, Ltd.) Model Gulfstream G150 airplanes. This AD was prompted by...: 2013-03-23 Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries,...

  1. 76 FR 70040 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

    Science.gov (United States)

    2011-11-10

    ... Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Airplanes AGENCY... previously held by Israel Aircraft Industries, Ltd.) Model Galaxy and Gulfstream G150 airplanes; and...: 2011-23-07 Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries,...

  2. 77 FR 44432 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

    Science.gov (United States)

    2012-07-30

    ... Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Airplanes AGENCY... previously held by Israel Aircraft Industries, Ltd.) Model Astra SPX, 1125 Westwind Astra, and Gulfstream 100... new AD: 2012-15-06 Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

  3. 76 FR 20971 - Eagle Rock Desoto Pipeline, L.P.; Notice of Filing

    Science.gov (United States)

    2011-04-14

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Eagle Rock Desoto Pipeline, L.P.; Notice of Filing Take notice that on April 7, 2011, Eagle Rock Desoto Pipeline, L.P. filed a revised Statement of Operating Conditions...

  4. 77 FR 12867 - Accreditation of Saybolt LP, as a Commercial Laboratory

    Science.gov (United States)

    2012-03-02

    ... SECURITY U.S. Customs and Border Protection Accreditation of Saybolt LP, as a Commercial Laboratory AGENCY... of Saybolt LP, as a commercial laboratory. SUMMARY: Notice is hereby given that, pursuant to 19 CFR... provisions of 19 CFR 151.12. Anyone wishing to employ this entity to conduct laboratory analyses...

  5. 75 FR 70939 - Approval of SAYBOLT LP, as a Commercial Gauger and Laboratory

    Science.gov (United States)

    2010-11-19

    ... SECURITY Customs and Border Protection Approval of SAYBOLT LP, as a Commercial Gauger and Laboratory AGENCY... and approval of Saybolt LP, as a commercial gauger and laboratory. SUMMARY: Notice is hereby given... this entity to conduct laboratory analyses and gauger services should request and receive...

  6. ON THE WEIGHTED VARIABLE EXPONENT AMALGAM SPACE W (Lp(x), Lqm)

    Institute of Scientific and Technical Information of China (English)

    A.Turan GURKANLI; Ismail AYDIN

    2014-01-01

    In [4] , a new family W (Lp(x), Lqm) of Wiener amalgam spaces was defined and investigated some properties of these spaces, where local component is a variable exponent Lebesgue space Lp(x) (R) and the global component is a weighted Lebesgue space Lqm (R). This present paper is a sequel to our work [4]. In Section 2, we discuss necessary and sufficient conditions for the equality W Lp(x), Lqm=Lq (R) . Later we give some characterization of Wiener amalgam space WLp(x), Lqm. In Section 3 we define the Wiener amalgam space W FLp(x),Lq m and investigate some properties of this space, where F Lp(x) is the image of Lp(x) under the Fourier transform. In Section 4, we discuss boundedness of the Hardy-Littlewood maximal operator between some Wiener amalgam spaces.

  7. Provision of CT Scanning Capability to VA/DoD (Veterans Administration/ Department of Defense) Health Care Facilities through a Shared Mobile CT Unit: A Feasibility Study

    Science.gov (United States)

    1984-07-27

    Hill, Alan L.; and Lange , Paul H. "Use of CT to Reduce Understaging in Prostatic Cancer: Comparison with Conventional Staging Techniques." American...November 1982): 427-29. 24. Firooznia, Hossein; Benjamin, Vallo; Kricheff, Irvin I.; Rafii, Mahvash; and Golimbu, Cornelia . "CT of Lumbar Spine Disk...Lloyd and Abernathy, David L. "Diagnostic Imaging Procedures Volume in the United States." Radiology 146 (March 1983): 851-3. 36. Lang , Eric K. "Angio

  8. An Analysis of Contracting Actions by United States Based Department of Defense Organizations to Support Operations Desert Shield and Desert Storm

    Science.gov (United States)

    1992-09-01

    Personal Interviews . . . . .... 36 Use of the Delphi Method . . . . . .... 37 Discussion of Investigative Questions . . . 39 Investigative Questions...the end of Desert Storm. Prior to Desert Shield the two manufacturers of injectors for atropine, a nerve agent antidote, were producing 60,000 units...two-stage approach was the formal phase, in which the Delphi technique was determined to be appropriate (Emory and Cooper, 1991:149). The data was

  9. Assessing Future Trends in the Defense Burdens of Western Nations

    Science.gov (United States)

    1993-04-01

    Summary Table 1). A weighted average for the four allies that spend most heavily on defense -- Japan , France, Germany, and the United Kingdom--is projected...military was dismantled. Among the largest allies, Japan represents the other extreme. Japanese defense spending as a percentage of GDP is projected to...January 1993. d. Weighted average for Japan , France, Germany, and the United Kingdom--countries that spend the greatest amounts on defense . e The 1990

  10. 78 FR 48177 - Purdue Pharma L.P.; Withdrawal of Approval of a New Drug Application for Oxycontin

    Science.gov (United States)

    2013-08-07

    .... FDA-2013-N-0883] Purdue Pharma L.P.; Withdrawal of Approval of a New Drug Application for Oxycontin...) Extended-Release Tablets, held by Purdue Pharma L.P. (Purdue), One Stamford Forum, Stamford, CT...

  11. 78 FR 32294 - DeltaPoint Capital IV, L.P., DeltaPoint Capital IV (New York), L.P., License No. 02/02-0662,02/02...

    Science.gov (United States)

    2013-05-29

    ... ADMINISTRATION DeltaPoint Capital IV, L.P., DeltaPoint Capital IV (New York), L.P., License No. 02/02-0662,02/02-0661; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that DeltaPoint Capital IV, L.P. and DeltaPoint Capital IV (New York),...

  12. Austere Defense: Challenges and Opportunities

    Science.gov (United States)

    2014-01-01

    military advice while acquiescing to divestitures, and effectively executing the austere defense cuts required by current law through 2019 and...Could it be that our assessments of risk have, over time, become too conservative? In- deed, even with the effects of full sequestration the United... crunch . Look- ing at overhead, as Douglas Macgregor of Politico magazine reminds us, during World War II, only four four-star generals commanded a

  13. Western Hemisphere Defense Policy Statement

    Science.gov (United States)

    2012-10-01

    El Salvador, Guatemala, Honduras , Paraguay, Peru and Uruguay have contributed to or led multi-national security operations and United Nations (UN...impact on regional and global peace and security and reflect the new realities of defense cooperation in the hemisphere. Working with Canada and...Mexico, DoD remains prepared to deter and defeat direct threats to our homeland. We partner with Canada on regional security issues such as an evolving

  14. Defense Globalization: Impacts on the United States Defense Acquisition System

    Science.gov (United States)

    2007-12-01

    munitions and sub-systems to fit these U.S. platforms. One such case involved Rafael developing the Popeye missile to be used on the Israeli...version of the McDonnell Douglas F-4E. In the late 1980s, the USAF viewed the Popeye as a short- term solution to its requirement for smart munitions and...purchased the Popeye directly “off the shelf” from Rafael. The USAF then went on to partner with Rafael in modifying and marketing the munitions to

  15. 78 FR 62344 - Sabine Pass Liquefaction Expansion, LLC, Sabine Pass Liquefaction, LLC, and Sabine Pass LNG, L.P...

    Science.gov (United States)

    2013-10-18

    ... Sabine Pass LNG, L.P., Cheniere Creole Trail Pipeline, L.P.; Notice of Application Take notice that on... LNG, L.P. (collectively referred to as Sabine Pass) filed with the Federal Energy Regulatory..., construct, and operate additional liquefied natural gas (LNG) export facilities at the Sabine Pass...

  16. 78 FR 62614 - Guttman Energy, Inc., PBF Holding Company LLC v. Buckeye Pipe Line Company, L.P., Laurel Pipe...

    Science.gov (United States)

    2013-10-22

    ... Energy Regulatory Commission Guttman Energy, Inc., PBF Holding Company LLC v. Buckeye Pipe Line Company, L.P., Laurel Pipe Line Company, L.P.; Notice of Complaint Take notice that on October 15, 2013... Energy Regulatory Commission (Commission) a complaint against Buckeye Pipe Line Company L.P. and Laurel...

  17. 77 FR 11618 - Solutions Capital I, L.P.; Notice Seeking Exemption Under the Small Business Investment Act...

    Science.gov (United States)

    2012-02-27

    ... ADMINISTRATION Solutions Capital I, L.P.; Notice Seeking Exemption Under the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Solutions Capital I, L.P., 1100 Wilson Blvd., Suite 3000... Administration Rules and Regulations (13 CFR 107). Solutions Capital I, L.P., proposes to acquire debt...

  18. 78 FR 57444 - Eagle Fund III, L.P.; Notice Seeking Exemption Under the Small Business Investment Act, Conflicts...

    Science.gov (United States)

    2013-09-18

    ... ADMINISTRATION Eagle Fund III, L.P.; Notice Seeking Exemption Under the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Eagle Fund III, L.P., 101 S. Hanley Road, Suite 1250, St... Business Administration (``SBA'') Rules and Regulations. Eagle Fund III, L.P., provided debt and...

  19. 78 FR 57444 - Eagle Fund III-A, L.P.; Notice Seeking Exemption Under the Small Business Investment Act...

    Science.gov (United States)

    2013-09-18

    ... ADMINISTRATION Eagle Fund III-A, L.P.; Notice Seeking Exemption Under the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Eagle Fund III-A, L.P., 101 S. Hanley Road, Suite 1250, St... Business Administration (``SBA'') Rules and Regulations. Eagle Fund III-A, L.P., provided debt and...

  20. The role of lipoprotein-associated phospholipase A2 (Lp-PLA₂) in cardiovascular disease.

    Science.gov (United States)

    Ikonomidis, Ignatios; Michalakeas, Christos A; Lekakis, John; Parissis, John; Anastasiou-Nana, Maria

    2011-05-01

    Lipoprotein-associated Phospholipase A2 (Lp-PLA(2)) is an enzyme that belongs to the A2 Phospholipase superfamily and is produced by inflammatory cells that are involved in the process of atherogenesis. Even though there is controversy in current bibliography whether Lp-PLA(2) exerts proatherogenic or anti-atherogenic properties, the weight of evidence suggests a pro-atherogenic role for this protein. Lp-PLA(2) is detected in human atherosclerotic lesions and elevated Lp-PLA(2) levels are associated with an increased risk of cardiovascular events and adverse events in patients with coronary artery disease independently of traditional risk factors and other markers of inflammation. It has been recently shown that direct pharmacological inhibition of Lp-PLA(2) activity exerts beneficiary effects on the atherosclerotic process. This finding is most interesting since it could offer a novel target for therapeutic intervention in patients suffering from cardiovascular disease. The purpose of this review article is to report on the role of Lp-PLA(2) in cardiovascular diseases and to enlighten the putative pathophysiologic mechanisms by which this protein exerts its effect on cardiovascular function. Additionally, the pharmacological interventions that influence Lp-PLA(2) activity and may offer a new approach for the treatment of atherosclerosis will be analyzed.

  1. Recognizing plant defense priming

    NARCIS (Netherlands)

    Martinez-Medina, A.; Flors, V.; Heil, M.; Mauch-Mani, B.; Pieterse, C.M.J.; Pozo, M.J.; Ton, J.; Van Dam, N.M.; Conrath, U.

    2016-01-01

    Defense priming conditions diverse plant species for the superinduction of defense, often resulting in enhanced pest and disease resistance and abiotic stress tolerance. Here, we propose a guideline that might assist the plant research community in a consistent assessment of defense priming in plant

  2. TRAC-PF1/MOD1 post-test calculations of the OECD (Organisation for Economic Co-operation and Development) LOFT experiment LP-SB-2

    Energy Technology Data Exchange (ETDEWEB)

    Pelayo, F. (UKAEA Atomic Energy Establishment, Winfrith (UK))

    1990-12-01

    An analysis of the OECD-LOFT-LP-SB-2 experiment making use of TRAC-PF1/MOD1 is described in the report. LP-SB2 experiment studies the effect of a delayed pump trip in a small break LOCA scenario with a 3 inches equivalent diameter break in the hot leg of a commercial PWR operating at full power. The experiment was performed on 14 July 1983 in the LOFT facility at the Idaho National Engineering Laboratory under the auspices of the Organization for Economic Co-operation and Development (OECD). This analysis presents an evaluation of the code capability in reproducing the complex phenomena which determined the LP-SB-2 transient evolution. the analysis comprises the results obtained from two different runs. The first run is described in detail analysing the main variables over two time spans: short and longer term. Several conclusions are drawn and then a second run testing some of these conclusions is shown. All of the calculations were preformed at the United Kingdom Atomic Energy Establishment at Winfrith under the auspices of an agreement between the UKAEA (United Kingdom Atomic Energy Authority) and the Consejo de Seguridad Nuclear Espanol (CSN). 16 refs., 64 figs., 6 tabs.

  3. MULTIPLIERS AND TENSOR PRODUCTS OF WEIGHTED LP-SPACES

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Let G be a locally compact uninmodular group with Haar measure rmdx and ω be the Beurling's weight function on G (Reiter, [10]). In this paper the authors define a space APωq,q (G) and prove that Aωp,q (G) is a translation invariant Banach space. Furthermore the authors discuss inclusion properties and show that if G is a locally compact abelian group then Aωp,q (G) admits an approximate identity bounded in L1ω. (G). It is also proved that the space Lpωp (G) L1ω lPω(G) is isometrically isomorphic to the space Apω.q (G) and the space of multipliers from Lωp (G) to Lqωq-1 (G) is isometrically isomorphic to the dual of the space Aωp,q (G) iff G satisfies a property Ppq. At the end of this work it is showed that if G is a locally compact abelian group then the space of all multipliers from L1ω (G) to Aωp,q (G) is the space Aωp,q (G).

  4. A note on "A LP-based heuristic for a time-constrained routing problem"

    OpenAIRE

    Muter, İbrahim; Muter, Ibrahim; Birbil, Ş. İlker; Birbil, S. Ilker; Bülbül, Kerem; Bulbul, Kerem; Şahin, Güvenç; Sahin, Guvenc

    2012-01-01

    Avella et al. (2006) [Avella, P., D'Auria, B., Salerno, S. (2006). A LP-based heuristic for a time-constrained routing problem. European Journal of Operational Research 173:120-124] investigate a time-constrained routing (TCR) problem. The core of the proposed solution approach is a large-scale linear program (LP) that grows both row- and column-wise when new variables are introduced. Thus, a column-and-row generation algorithm is proposed to solve this LP optimally, and an optimality conditi...

  5. Neural Network Based Modeling and Analysis of LP Control Surface Allocation

    Science.gov (United States)

    Langari, Reza; Krishnakumar, Kalmanje; Gundy-Burlet, Karen

    2003-01-01

    This paper presents an approach to interpretive modeling of LP based control allocation in intelligent flight control. The emphasis is placed on a nonlinear interpretation of the LP allocation process as a static map to support analytical study of the resulting closed loop system, albeit in approximate form. The approach makes use of a bi-layer neural network to capture the essential functioning of the LP allocation process. It is further shown via Lyapunov based analysis that under certain relatively mild conditions the resulting closed loop system is stable. Some preliminary conclusions from a study at Ames are stated and directions for further research are given at the conclusion of the paper.

  6. Soviet debate on missile defense

    Energy Technology Data Exchange (ETDEWEB)

    Parrott, B.

    1987-04-01

    Although the Strategic Defense Initiative (SDI) is meant to cope with the danger of a Soviet nuclear attack, the recent US debate over SDI has paid surprisingly little attention to Soviet views of ballistic missile defense. Despite the existence of a substantial body of pertinent scholarship, the debate has failed to take adequate account of major changes in Soviet ballistic missile defense policy since the mid-1960s. It has also neglected the links between current Soviet military policy and broader Soviet political and economic choices. The Soviets regard SDI not as a novel undertaking to reduce the risks of nuclear war but as an extension of the geopolitical competition between the superpowers. This competition has been dominated in the 1980s, in the Soviet view, by sharply increased US assertiveness and the decline of detente. Viewing SDI as a manifestation of these general trends, Soviet decision makers find the prospect of an unregulated race in ballistic missile defenses and military space technologies deeply unsettling. The deterioration of superpower relations has raised serious doubts in Moscow about the wisdom of Soviet external policy during the 1970s and has provoked sharp internal differences over policy toward the US. Already highly suspicious of the Reagan administration, the elite is united by a general conviction that SDI is an American gambit that may ultimately undercut past Soviet strategic gains and pose a grave new threat to Soviet security. 14 references.

  7. Meningococcal Serogroup B Bivalent rLP2086 Vaccine Elicits Broad and Robust Serum Bactericidal Responses in Healthy Adolescents

    DEFF Research Database (Denmark)

    Vesikari, Timo; Østergaard, Lars Jørgen; Diez-Domingo, Javier

    2015-01-01

    BACKGROUND: Neisseria meningitidis serogroup B (MnB) is a leading cause of invasive meningococcal disease in adolescents and young adults. A recombinant factor H binding protein (fHBP) vaccine (Trumenba(®); bivalent rLP2086) was recently approved in the United States in individuals aged 10-25 years...... ≥1:8 after 3 doses ranged from 91.7% to 95.0%, 98.9% to 99.4%, 88.4% to 89.0%, and 86.1% to 88.5% for MnB test strains expressing vaccine--heterologous fHBP variants A22, A56, B24, and B44, respectively. After 2 doses, responses ranged from 90.8% to 93.5%, 98.4% to 100%, 69.1% to 81.1%, and 70...... was well tolerated. CONCLUSIONS: Bivalent rLP2086 was immunogenic and well tolerated when administered in 2 or 3 doses. Three doses yielded the most robust hSBA response rates against MnB strains expressing vaccine-heterologous subfamily B fHBPs....

  8. 77 FR 38128 - Withdrawal of TORP Terminal LP, Bienville Offshore Energy Terminal Liquefied Natural Gas (LNG...

    Science.gov (United States)

    2012-06-26

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION Maritime Administration Withdrawal of TORP Terminal LP, Bienville Offshore Energy Terminal Liquefied Natural Gas (LNG) Deepwater Port Application AGENCY: Maritime Administration, DOT. ACTION: Deepwater...

  9. LP-tee pikeneb Tartust Pärnuni / Sirje Pärismaa

    Index Scriptorium Estoniae

    Pärismaa, Sirje, 1958-

    2015-01-01

    Norrast pärit tõenduspõhist koostöökultuuri arendava LP-mudeliga (learning environment and pedagogical analysis) on liitumas seitse kooli Pärnust, Viljandist, Puhjast, Tartust ning kolm lasteaeda

  10. α-Automated Reasoning Method Based on Lattice-Valued Propositional Logic LP(X)

    Institute of Scientific and Technical Information of China (English)

    王伟; 徐扬; 王学芳

    2002-01-01

    This paper is focused on automated reasoning based on classical propositional logic and lattice-valued propositional logic LP(X). A new method of automated reasoning is given, and the soundness and completeness theorems of this method are proved.

  11. LibraryH3lp: A New Flexible Chat Reference System

    Directory of Open Access Journals (Sweden)

    Pam Sessoms

    2008-09-01

    Full Text Available LibraryH3lp is an integrated IM and web chat system designed specifically for Virtual Reference services in libraries. The software was designed for, and is currently used by, a night-time chat reference collaboraton between several large academic libraries. LibraryH3lp is designed for the workflow of chat reference, supporting multiple simultaneous operators and routing to queues of operators in a particular service area. It also supports web page embeddable chat 'widgets', as well as simultaneous gateways to multiple IM protocols. This article discusses the motivation for the development of the software, and provides an overview of LibraryH3lp's features and technical architecture. Parts of LibraryH3lp are available as open source. The complete application is available as a low-cost hosted service, and will eventually be available to be licensed for local hosting.

  12. Mixed Lp Estimators Variety for Model Order Reduction in Control Oriented System Identification

    Directory of Open Access Journals (Sweden)

    Christophe Corbier

    2015-01-01

    Full Text Available A new family of MLE type Lp estimators for model order reduction in dynamical systems identification is presented in this paper. A family of Lp distributions proposed in this work combines Lp2 (1Lp1 (0

  13. Characterization of LpGPAT Gene in Lilium pensylvanicum and Response to Cold Stress

    Directory of Open Access Journals (Sweden)

    Shao-kun Sun

    2015-01-01

    Full Text Available LpGPAT was obtained from L. pensylvanicum using RT-PCR and rapid amplification of cDNA ends. The cloned full-length cDNA was 1544 bp; it encoded 410 amino acids and had a molecular size of 46 KDa. The nucleic acid sequence analysis showed that it shared high homology with other known GPATs. SMAT result suggests that there is a PlsC that exists in 176-322 amino acid sequence of LpGAPT; it means LpGPAT protein is a member of the family of acyltransferase and has acyltransferase enzymatic activity. Result of real-time quantitative PCR and semiquantitative PCR support LpGPAT gene is definitely induced by low temperature stress.

  14. Poly-(R)-3-hydroxybutyrates (PHB) are Atherogenic Components of Lipoprotein Lp(a).

    Science.gov (United States)

    Reusch, Rosetta N

    2015-12-01

    The hypothesis is that poly-(R)-3-hydroxybutyrates (PHB), linear polymers of the ketone body, R-3-hydroxybutyrate (R-3HB), are atherogenic components of lipoprotein Lp(a). PHB are universal constituents of biological cells and are thus components of all foods. Medium chain-length PHB (70%) are absorbed by albumin, which transports them to the liver for disposal. When the amount of PHB in the diet exceed the capacity of albumin to safely remove them from the circulation, the excess PHB remain in the lipid core of LDL particles that become constituents of lipoprotein Lp(a), and contribute to the formation of arterial deposits. In summary, the presence of PHB – water-insoluble, dense, viscous, adhesive polymers – in the lipid cores of the LDL moieties of Lp(a) particles supports the hypothesis that PHB are atherogenic components of Lp(a).

  15. LP-tee pikeneb Tartust Pärnuni / Sirje Pärismaa

    Index Scriptorium Estoniae

    Pärismaa, Sirje, 1958-

    2015-01-01

    Norrast pärit tõenduspõhist koostöökultuuri arendava LP-mudeliga (learning environment and pedagogical analysis) on liitumas seitse kooli Pärnust, Viljandist, Puhjast, Tartust ning kolm lasteaeda

  16. 78 FR 17389 - Texas Eastern Transmission, LP; Notice of Application for Certificate of Public Convenience and...

    Science.gov (United States)

    2013-03-21

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Texas Eastern Transmission, LP; Notice of Application for Certificate of Public Convenience and Necessity and Authorization for Abandonment Take notice that on February...

  17. 76 FR 45246 - Tesoro Refining and Marketing Company v. SFPP, L.P.; Notice of Complaint

    Science.gov (United States)

    2011-07-28

    ..., L.P. ] in FERC Tariff Nos. 194.1.0, 195.1.0, 196.3.0, 197.1.0, 198.3.0, 199.1.0, and 200.1.0 are... Energy Regulatory Commission Tesoro Refining and Marketing Company v. SFPP, L.P.; Notice of Complaint... the Energy Policy Act of 1992 (EPAct), Tesoro Refining and Marketing Company (Tesoro) filed a formal...

  18. Pengaruh Penerapan Sistem Informasi Akuntansi Terhadap Pengambilan Keputusan Pada Politeknik Unggul LP3M Medan

    OpenAIRE

    Nasir, Miftah Faridh

    2014-01-01

    The purpose of this study was to determine how the analysis of the application of information systems in the management accounting can affect decision-making at the Polytechnic Unggul LP3M Medan and to determine the accounting information system to ensure accurate decision-making in a company. Primary data were collected by interviewing management and data documenting the Polytechnic Superior LP3M Medan. The analytical method used is descriptive. Hypothesis in this study is a significa...

  19. A Generalization of the Mean Size Formula of Wavelet Packets in Lp

    Institute of Scientific and Technical Information of China (English)

    Song LI; Guo Mao WANG; Zhi Song LIU

    2005-01-01

    The purpose of this paper is to investigate the mean size formula of wavelet packets in Lp for 0 < p ≤∞. We generalize a mean size formula of wavelet packets given in terms of the p-norm joint spectral radius and we also give some asymptotic formulas for the Lp-norm or quasi-norm on the subdivision trees. All results will be given in the general setting.

  20. Path properties of lp-valued Gaussian random fields

    Institute of Scientific and Technical Information of China (English)

    Yong-Kab; CHOI

    2007-01-01

    [1]Csáki E,Cs(o)rg(o) M.Inequalities for increments of stochastic processes and moduli of continuity.Ann Probab,20:1031-1052 (1992)[2]Csáki E,Cs(o)rg(o) M,Shao Q M.Fernique type inequalities and moduli of continuity for l2-valued Ornstein-Uhlenbeck Processes.Ann In st Henri Poincare Probabilities et Statistiques,28:479-517 (1992)[3]Csáki E,Cs(o)rg(o) M,Shao Q M.Moduli of continuity for lp-valued Gaussian processes.Acta Sci Math,60:149-175 (1995)[4]Cs(o)rg(o) M,Shao Q M.Strong limit theorems for large and small increments of lp-valued Gaussian Processes.Ann Probab,21:1958-1990 (1993)[5]Cs(o)rg(o) M,Shao Q M.On almost sure limit inferior for B-valued stochastic processes and applications.Probab Theory & Rel Fields,99:29-54 (1994)[6]Lin Z Y,Quin Y C.On the increments of l∞-valued Gaussian processes.In:Szyszkowicz B,ed.Asymptotic Methods in Probability and Statistics.Elsevier Science B V,1998,293-302[7]Choi Y K.Erd(o)s-Rényi-type laws applied to Gaussian processes.J Math Kyoto Univ,31(3):191-217(1991)[8]Csáki E,Cs(o)rg(o) M,Lin Z Y,et al.On infinite series of independent Ornstein-uhlenbeck processes.Stoch Proc & their Appl,39:25-44 (1991)[9]Cs(o)rg(o) M,Révész P.How big are the increments of a Wiener process? Ann Probab,7(4):731-737 (1979)[10]Cs(o)rg(o) M,Révész P.Strong Approximations in Probability and Statistics.New York:Academic Press,1981[11]Lin Z Y,Lu C R.Strong Limit Theorems.Hong Kong:Kluwer Academic Publ,1992[12]Ortega J.On the size of the increments of non-stationary Gaussian processes.Stoch Proc & Their Appl,18:47-56 (1984)[13]Zhang L X.A note on liminfs for increments of a fractional Brownian motion.Acta Math Hungar,76:145-154 (1997)[14]K(o)no N.The exact modulus of continuity for Gaussian processes taking values of finite dimensional normed space.Trends in Probab & Related Analysis,SAP'96.Singapore:World Scientific,1996.pp.219-232[15]Lin Z Y,Hwang K S.On the increments of a d-dimensional Gaussian process.J Korean Math Soc,42(6):1215-1230 (2005

  1. LpMab-23: A Cancer-Specific Monoclonal Antibody Against Human Podoplanin.

    Science.gov (United States)

    Yamada, Shinji; Ogasawara, Satoshi; Kaneko, Mika K; Kato, Yukinari

    2017-04-07

    Human podoplanin (hPDPN), the ligand of C-type lectin-like receptor-2, is involved in cancer metastasis. Until now, many monoclonal antibodies (mAbs) have been established against hPDPN. However, it is still difficult to develop a cancer-specific mAb (CasMab) against hPDPN because the protein sequence of hPDPN expressed in cancer cells is the same as that in normal cells. Herein, we report LpMab-23 of the mouse IgG1 subclass, a novel CasMab against hPDPN. In an immunohistochemical analysis, LpMab-23 reacted with tumor cells of human oral cancer, but did not react with normal cells such as lymphatic endothelial cells (LECs). In contrast, LpMab-17, another anti-hPDPN mAb, reacted with both tumor cells and LECs. Furthermore, flow cytometric analysis revealed that LpMab-23 reacted with hPDPN-expressing cancer cell lines (LN319, RERF-LC-AI/hPDPN, Y-MESO-14/hPDPN, and HSC3/hPDPN) but showed little reaction with normal cells (LECs and HEK-293T), although another anti-hPDPN mAb, LpMab-7, reacted with both hPDPN-expressing cancer cells and normal cells, indicating that LpMab-23 is a CasMab against hPDPN.

  2. The effectiveness of the U.S. missile defense capabilities as a deterrent to the North Korean missile threat

    OpenAIRE

    Gipson, Issac G.

    2007-01-01

    Over the last five years, America has placed an ever-increasing emphasis on missile defense and currently spends nearly $10 billion annually on its development. The United States' current missile Defense system is integrated; it depends on the cooperation of defensive elements aboard ships, on land, in the air and space. The objective is to provide a layered defense with multiple opportunities to destroy an incoming missile. By investing heavily in missile defense technology, the United ...

  3. Moving Target Defense

    CERN Document Server

    Jajodia, Sushil; Swarup, Vipin; Wang, Cliff; Wang, X Sean

    2011-01-01

    Moving Target Defense: Creating Asymmetric Uncertainty for Cyber Threats was developed by a group of leading researchers. It describes the fundamental challenges facing the research community and identifies new promising solution paths. Moving Target Defense which is motivated by the asymmetric costs borne by cyber defenders takes an advantage afforded to attackers and reverses it to advantage defenders. Moving Target Defense is enabled by technical trends in recent years, including virtualization and workload migration on commodity systems, widespread and redundant network connectivity, instr

  4. Selective 5-HT7 receptor agonists LP 44 and LP 211 elicit an analgesic effect on formalin-induced orofacial pain in mice

    Directory of Open Access Journals (Sweden)

    Kadriye DEMİRKAYA

    Full Text Available ABSTRACT The most recently identified serotonin (5-HT receptor is the 5-HT7 receptor. The antinociceptive effects of a 5-HT7 receptor agonist have been shown in neuropathic and inflammatory animal models of pain. A recent study demonstrated the functional expression of 5-HT7 receptors in the substantia gelatinosa (SG of the trigeminal subnucleus caudalis, which receives and processes orofacial nociceptive inputs. Objective To investigate the antinociceptive effects of pharmacological activation of 5-HT7 receptors on orofacial pain in mice. Material and Methods Nociception was evaluated by using an orofacial formalin test in male Balb-C mice. Selective 5-HT7 receptor agonists, LP 44 and LP 211 (1, 5, and 10 mg/kg, were given intraperitoneally 30 min prior to a formalin injection. A bolus of 10 µl of 4% subcutaneous formalin was injected into the upper lip of mice and facial grooming behaviors were monitored. The behavioral responses consisted of two distinct periods, the early phase corresponding to acute pain (Phase I: 0–12 min and the late phase (Phase II: 12–30 min. Results LP 44 and LP 211 (1, 5, and 10 mg/kg produced an analgesic effect with reductions in face rubbing time in both Phase I and Phase II of the formalin test. Conclusion Our results suggest that 5-HT7 receptor agonists may be promising analgesic drugs in the treatment of orofacial pain.

  5. Selective 5-HT7 receptor agonists LP 44 and LP 211 elicit an analgesic effect on formalin-induced orofacial pain in mice

    Science.gov (United States)

    DEMİRKAYA, Kadriye; AKGÜN, Özlem Martı; ŞENEL, Buğra; ÖNCEL TORUN, Zeynep; SEYREK, Melik; LACİVİTA, Enza; LEOPOLDO, Marcello; DOĞRUL, Ahmet

    2016-01-01

    ABSTRACT The most recently identified serotonin (5-HT) receptor is the 5-HT7 receptor. The antinociceptive effects of a 5-HT7 receptor agonist have been shown in neuropathic and inflammatory animal models of pain. A recent study demonstrated the functional expression of 5-HT7 receptors in the substantia gelatinosa (SG) of the trigeminal subnucleus caudalis, which receives and processes orofacial nociceptive inputs. Objective To investigate the antinociceptive effects of pharmacological activation of 5-HT7 receptors on orofacial pain in mice. Material and Methods Nociception was evaluated by using an orofacial formalin test in male Balb-C mice. Selective 5-HT7 receptor agonists, LP 44 and LP 211 (1, 5, and 10 mg/kg), were given intraperitoneally 30 min prior to a formalin injection. A bolus of 10 µl of 4% subcutaneous formalin was injected into the upper lip of mice and facial grooming behaviors were monitored. The behavioral responses consisted of two distinct periods, the early phase corresponding to acute pain (Phase I: 0–12 min) and the late phase (Phase II: 12–30 min). Results LP 44 and LP 211 (1, 5, and 10 mg/kg) produced an analgesic effect with reductions in face rubbing time in both Phase I and Phase II of the formalin test. Conclusion Our results suggest that 5-HT7 receptor agonists may be promising analgesic drugs in the treatment of orofacial pain. PMID:27383702

  6. Dynamic defense workshop :

    Energy Technology Data Exchange (ETDEWEB)

    Crosby, Sean Michael; Doak, Justin E.; Haas, Jason Juedes.; Helinski, Ryan; Lamb, Christopher C.

    2013-02-01

    On September 5th and 6th, 2012, the Dynamic Defense Workshop: From Research to Practice brought together researchers from academia, industry, and Sandia with the goals of increasing collaboration between Sandia National Laboratories and external organizations, de ning and un- derstanding dynamic, or moving target, defense concepts and directions, and gaining a greater understanding of the state of the art for dynamic defense. Through the workshop, we broadened and re ned our de nition and understanding, identi ed new approaches to inherent challenges, and de ned principles of dynamic defense. Half of the workshop was devoted to presentations of current state-of-the-art work. Presentation topics included areas such as the failure of current defenses, threats, techniques, goals of dynamic defense, theory, foundations of dynamic defense, future directions and open research questions related to dynamic defense. The remainder of the workshop was discussion, which was broken down into sessions on de ning challenges, applications to host or mobile environments, applications to enterprise network environments, exploring research and operational taxonomies, and determining how to apply scienti c rigor to and investigating the eld of dynamic defense.

  7. Equalizer Complexity for 6-LP Mode 112 Gbit/s m-ary DP-QAM Space Division Multiplexed Transmission in Strongly Coupled Few-Mode-Fibers

    DEFF Research Database (Denmark)

    Asif, Rameez; Ye, Feihong; Morioka, Toshio

    2015-01-01

    We have quantified equalizer complexity for transmitting dual-polarized 6-LP modes (LP01, LP11a, LP11b, LP21a, LP21b and LP02) of 112 Gbit/s m-ary QAM (m=4, 16, 32, 64, 256) single carrier signals over 20 km step-index few-mode fiber. The transmitted signals are strongly coupled and recovered using...... 12×12 multiple-input multiple-output (MIMO) adaptive digital signal processing (DSP). Time domain equalization (TDE) is realized to implement the linear adaptive MIMO module that is implemented in blind mode using conventional constant-modulusalgorithm (CMA) for finite impulse response (FIR) adaptive...

  8. 植物乳杆菌LpT1和LpT2大鼠体内降胆固醇特性%Cholesterol-degrading in mice by Lactobacillus plantarum LpT1 and LpT2 in vivo

    Institute of Scientific and Technical Information of China (English)

    于平; 汪晓辉

    2012-01-01

    [Objective] To explore the cholesterol-degrading in mice by Lactobacillus plantarum LpT1 and LpT2 in vivo. [Methods] The hypercholesterolemia mice were randomly classified into 4 groups: A, B, C and D and fed with strain LpTl, LpT2, lovastatin and distilled water, respectively, and then TC, TG, HDL-C, LDL-C and AI were determined. The tissue slice of liver was made and observed by transmission electron microscope. [Results] The hypercholesterolemia mice model was successfully constructed after feeding the hypercholesterol forage for 7 days. Lactobacillus plantarum LpTl and the positive control lovastatin could significantly degrade the total cholesterol content (p<0.01 ) after 28 days, higher than Lactobacillus plantarum LpT2 (p<0.05). However, the negative control water could not degrade it. The transmission electron microscope result showed that the strains could effectively regulate the lipid metabolism to develop towards the regular trend after they were absorbed into the intestines. [Conclusion] The results further laid foundation for studying the cholesterol- degrading mechanism by Lactobacillus plantarum in vivo.%[目的]探讨植物乳杆菌LpT1和LpT2大鼠体内降胆固醇特性.[方法]将高脂血症的大鼠随机分成4组,分别进行灌胃.A、B、C和D组分别灌胃菌株LpT1、菌株LpT2、洛伐他汀和蒸馏水.灌胃28d后,断尾采血,分离血清,分别测定总胆固醇、总甘油三酯、高密度脂蛋白胆固醇和低密度脂蛋白胆固醇的含量并进行肝脏组织切片的制作与电镜观察.[结果]饲喂高脂饲料7d后,成功构建出高脂血症大鼠模型.植物乳杆菌菌株LpT1和阳性对照洛伐他汀降胆固醇效果极其显著(p<0.01),菌株LpT2次之(p<0.05),而阴性对照水几乎无降胆固醇效果.从电镜扫描结果看,植物乳杆菌LpT1和LpT2在大鼠肠道中定植后,能很好的调节肝脏代谢脂类物质朝着正常化趋势发展.[结论]研究结果为进一步明确植物乳杆菌

  9. LP-SVM在CUDA架构上的加速实现

    Institute of Scientific and Technical Information of China (English)

    兰远东

    2014-01-01

    为了能在PC机上处理大规模数据集问题,提出了使用CUDA架构对LP-SVM的加速实现方法。该方法针对PC机内存小的缺点,对SVM的分解算法进行改编,得到求解LP-SVM的分解算法。LP-SVM分解算法每次只需要求解一个小规模的线性规划问题,避免一次性把所有训练数据都装进内存。同时把求解线性规划中比较耗时的矩阵运算,移植到CUDA上进行,提高了求解效率。实验结果表明:LP-SVM算法在经过CUDA加速以后,算法的执行效率提高了10-35倍。%In order to handle the problem of large-scale data processing on PC, an acceleration method which uses the CUDA architecture to accelerate the implementation of LP-SVM is proposed. Considering the limit memory of PC, the decomposition algorithm of SVM is modified to solve the LP-SVM. Each time the new decomposition algorithm of only solves a smal-scale linear programming problem and avoids loading al the training data into memory. The comparative time-consuming parts of linear programming are migrated to CUDA platform, which has greatly improved calculation eficiency. Experimental results show that the efficiency of LP-SVM algorithm has been speeded up by 10 to 35 times.

  10. Willingness to pay for defense against weapons of mass destruction.

    Science.gov (United States)

    Mulvaney, J M; LaBarre, D; Pastel, R; Landauer, M

    2001-12-01

    A survey assessed the willingness to pay for defense against weapons of mass destruction. The results were evaluated according to the benefit to society. The results indicated preferences for increased spending on intelligence gathering, training, and equipment. We concluded that the United States is spending less for weapons of mass destruction defense than the sample population was willing to pay.

  11. Globalization and Its Implications for the Defense Industrial Base

    Science.gov (United States)

    2007-02-01

    pursued three strategies: buying relatively small defense units from diversified U.S. conglomerates (like General Motors and TRW); acquiring defense...13.9 percent).121 European companies have been very successful in China: Volkswagen makes the country’s most popular brand of cars, and Siemens is the

  12. Unfolding Green Defense

    DEFF Research Database (Denmark)

    Larsen, Kristian Knus

    2015-01-01

    consumption in military operations, defense expenditure, energy security, and global climate change. The report then proceeds to introduce the NATO Green Defence Framework before exploring specific current uses of green technologies and green strategies for defense. The report concludes that a number...

  13. Avian host defense peptides

    NARCIS (Netherlands)

    Cuperus, Tryntsje; Coorens, M.; van Dijk, A.; Haagsman, H.P.

    2013-01-01

    Host defense peptides (HDPs) are important effector molecules of the innate immune system of vertebrates. These antimicrobial peptides are also present in invertebrates, plants and fungi. HDPs display broad-spectrum antimicrobial activities and fulfill an important role in the first line of defense

  14. Defense Mechanisms: A Bibliography.

    Science.gov (United States)

    Pedrini, D. T.; Pedrini, Bonnie C.

    This bibliography includes studies of defense mechanisms, in general, and studies of multiple mechanisms. Defense mechanisms, briefly and simply defined, are the unconscious ego defendants against unpleasure, threat, or anxiety. Sigmund Freud deserves the clinical credit for studying many mechanisms and introducing them in professional literature.…

  15. Defense Industry Clusters in Turkey

    Directory of Open Access Journals (Sweden)

    Kadir Alpaslan Demir

    2016-06-01

    Full Text Available All countries strive for a capable national defense supported by a strong national defense industry. Supporting national defense with imported defense systems has many limitations and risks because the terms of arms trade agreements between countries may easily be influenced by the political climate of the signatories. As a result, establishing an independent national defense requires a strong national defense industry. Furthermore, exporting defense systems may be an important source of national income. National defense industries mostly consist of large-scale defense firms that have the resources required for big defense contracts. However, small to medium enterprises (SMEs do not have the necessary resources, therefore they are at a disadvantage. To overcome this handicap and be part of the business, defense industry clusters mostly consisting of SMEs are being established. Provided that there is good national planning and support in this area, defense clusters consisting of SMEs may play a significant role in industry. SMEs have a chance to offer specialized services, special or customized products when needed. As a result, large defense firms subcontract certain portions of defense projects to SMEs. Since 2010, Turkey has shown signs of continuous improvement in defense industry clustering. In parallel with these developments, this study discusses the importance of clustering in the defense industry, briefly presents the state of the Turkish defense industry as highlighted by national statistics, and presents the current status of defense clusters in Turkey. The novelty of this article consists in its assessment of Turkish defense clusters.

  16. The relation between Lp-PLA2 levels with periodic limb movements.

    Science.gov (United States)

    Bekci, Taha Tahir; Kayrak, Mehmet; Kiyici, Aysel; Ari, Hatem; Teke, Turgut; Maden, Emin; Akilli, Hakan

    2012-03-01

    Lipoprotein-associated phospholipase A2 (Lp-PLA2), a novel marker of vulnerable plaque to prone rupture, is a predictor of both cardiovascular event and cerebrovascular event, and highly sensitive-C-reactive protein (hs-CRP) is an acute-phase response protein implicated in a broad range of cardiovascular diseases. We aimed to examine the association between periodic limb movements in sleep (PLMs) with circulating Lp-PLA2 and hs-CRP levels in patients with PLMs. Seventy patients with newly diagnosed PLM with polysomnography were enrolled this study. Patients were divided into two groups according to PLM index (normal PLM index, PLM index, ≥15). Lp-PLA2 and hs-CRP concentrations were measured in serum samples by turbidimetric and nephelometric methods, respectively. The concentrations of these parameters were compared between two groups and correlation analysis was performed between PLMs and Lp-PLA2 and hs-CRP levels. Lp-PLA2 levels and hs-CRP were significantly increased in elevated PLM index group compared with the control group (206.8 ± 78.1 vs 157.8 ± 56.7, p = 0.003, and 4.2 ± 3.5 vs 2.4 ± 2.1, p = 0.02, respectively). PLM index was positively correlated with Lp-PLA2 levels (r = 0.40, p = 0.001) and hs-CRP (r = 0.24, p = 0.05). In the linear regression model, Lp-PLA2 was an independent predictor of PLM index (R(2) = 0.36, p = 0.005). This study demonstrated an independent linear relation between PLM index and Lp-PLA2. In addition, it was seen increased Lp-PLA2 and hs-CRP levels in patients with elevated PLM index. Based on these results, we can suggest that risk of vascular events may be increased in patients with PLMs and with increased PLM index.

  17. Student Papers on Strategic Defense Initiative.

    Science.gov (United States)

    1985-01-01

    force". The Army’s recent emphasis on maneuver and mobil - ity, and the employment of smaller units, demonstrates the utility of this doctrine...to forgo the use of defensive space systems, since some of the techonology now investigated could at least pro- tect missile sites, and make the

  18. Defense Advanced Research Projects Agency Strategic Plan

    Science.gov (United States)

    2007-02-01

    Autonomous Language Exploitation ...................................................................... 33 Figure 35: Bio-inspired "Big Dog" quadruped robot is... Acqusition , Technology and the United States, while creating Logistics Kenneth J. Krieg technological surprise for our • Under Secretaryof Defense for...working to maintain our global lead in this technology (Section 3.7). " Real-Time Accurate Language Translation: real-time machine language

  19. Analysis of error floor of LDPC codes under LP decoding over the BSC

    Energy Technology Data Exchange (ETDEWEB)

    Chertkov, Michael [Los Alamos National Laboratory; Chilappagari, Shashi [UNIV OF AZ; Vasic, Bane [UNIV OF AZ; Stepanov, Mikhail [UNIV OF AZ

    2009-01-01

    We consider linear programming (LP) decoding of a fixed low-density parity-check (LDPC) code over the binary symmetric channel (BSC). The LP decoder fails when it outputs a pseudo-codeword which is not a codeword. We propose an efficient algorithm termed the instanton search algorithm (ISA) which, given a random input, generates a set of flips called the BSC-instanton and prove that: (a) the LP decoder fails for any set of flips with support vector including an instanton; (b) for any input, the algorithm outputs an instanton in the number of steps upper-bounded by twice the number of flips in the input. We obtain the number of unique instantons of different sizes by running the ISA sufficient number of times. We then use the instanton statistics to predict the performance of the LP decoding over the BSC in the error floor region. We also propose an efficient semi-analytical method to predict the performance of LP decoding over a large range of transition probabilities of the BSC.

  20. Deterministic and randomized scheduling problems under the lp norm on two identical machines

    Institute of Scientific and Technical Information of China (English)

    LIN Ling; TAN Zhi-yi; HE Yong

    2005-01-01

    Parallel machine scheduling problems, which are important discrete optimization problems, may occur in many applications. For example, load balancing in network communication channel assignment, parallel processing in large-size computing, task arrangement in flexible manufacturing systems, etc., are multiprocessor scheduling problem. In the traditional parallel machine scheduling problems, it is assumed that the problems are considered in offline or online environment. But in practice, problems are often not really offline or online but somehow in-between. This means that, with respect to the online problem, some further information about the tasks is available, which allows the improvement of the performance of the best possible algorithms. Problems of this class are called semi-online ones. In this paper, the semi-online problem P2|decr|lp (p>1) is considered where jobs come in non-increasing order of their processing times and the objective is to minimize the sum of the lp norm of every machine's load. It is shown that LS algorithm is optimal for any lp norm, which extends the results known in the literature. Furthermore, randomized lower bounds for the problems P2|online|lp and P2|decr|lp are presented.

  1. Antioxidant and inflammatory aspects of lipoprotein-associated phospholipase A₂ (Lp-PLA₂): a review.

    Science.gov (United States)

    Silva, Isis T; Mello, Ana P Q; Damasceno, Nágila R T

    2011-09-28

    The association of cardiovascular events with Lp-PLA2 has been studied continuously today. The enzyme has been strongly associated with several cardiovascular risk markers and events. Its discovery was directly related to the hydrolysis of the platelet-activating factor and oxidized phospholipids, which are considered protective functions. However, the hydrolysis of bioactive lipids generates lysophospholipids, compounds that have a pro-inflammatory function. Therefore, the evaluation of the distribution of Lp-PLA2 in the lipid fractions emphasized the dual role of the enzyme in the inflammatory process, since the HDL-Lp-PLA2 enzyme contributes to the reduction of atherosclerosis, while LDL-Lp-PLA2 stimulates this process. Recently, it has been verified that diet components and drugs can influence the enzyme activity and concentration. Thus, the effects of these treatments on Lp-PLA2 may represent a new kind of prevention of cardiovascular disease. Therefore, the association of the enzyme with the traditional assessment of cardiovascular risk may help to predict more accurately these diseases.

  2. Pathophysiological role and clinical significance of lipoprotein-associated phospholipase A₂ (Lp-PLA₂) bound to LDL and HDL.

    Science.gov (United States)

    Tellis, Constantinos C; Tselepis, Alexandros D

    2014-01-01

    Lipoprotein-associated phospholipase A2 (Lp-PLA2), also named as platelet-activating factor (PAF)-acetylhydrolase, exhibits a Ca2+-independent phospholipase A2 activity and catalyzes the hydrolysis of the ester bond at the sn-2 position of PAF and oxidized phospholipids (oxPL). These phospholipids are formed under oxidative and inflammatory conditions, and may play important roles in atherogenesis. The vast majority of plasma Lp-PLA2 mass binds to low-density lipoprotein (LDL) while a smaller amount is associated with high-density lipoprotein (HDL). Lp-PLA2 is also bound to lipoprotein (a) [Lp(a)], very low-density lipoprotein (VLDL) and remnant lipoproteins. Several lines of evidence suggest that the role of plasma Lp-PLA2 in atherosclerosis may depend on the type of lipoprotein particle with which this enzyme is associated. Data from large Caucasian population studies have supported plasma Lp-PLA2 (primarily LDL-associated Lp-PLA2) as a cardiovascular risk marker independent of, and additive to, traditional risk factors. On the contrary, the HDL-associated Lp-PLA2 may express antiatherogenic activities and is also independently associated with lower risk for cardiac death. The present review presents data on the biochemical and enzymatic properties of Lp-PLA2 as well as its structural characteristics that determine the association with LDL and HDL. We also critically discuss the possible pathophysiological and clinical significance of the Lp- PLA2 distribution between LDL and HDL in human plasma, in view of the results of prospective epidemiologic studies on the association of Lp-PLA2 with future cardiovascular events as well the recent studies that evaluate the possible effectiveness of specific Lp-PLA2 inhibitors in reducing residual cardiovascular risk.

  3. Vector subdivision schemes in (Lp(Rs))r(1

    Institute of Scientific and Technical Information of China (English)

    LI; Song(

    2003-01-01

    [1]Chen, D. R., Jia, R. Q., Riemenschneider, S. D., Convergence of vector subdivision schemes in Sobolev spaces,Applied and Computational Harmonic Analysis, 2002, 12: 128-149.[2]Jia, R. Q., Riemenschneider, S. D., Zhou, D. X., Vector subdivision schemes and multiple wavelets, Math.Comp., 1998, 67: 1533-1563.[3]Heil, C., Colella, D., Matrix refinement equations: existence and uniqueness, J. Fourier Anal. Appl., 1996, 2:363-377.[4]Jiang, Q. T., Multivariate matrix refinement functions with arbitrary matrix dilation, Tran. Amer. Math.Soc., 1999, 351: 2407-2438.[5]Cavaretta, A. S., Dahmen, W., Micchelli, C. A., Stationary subdivision, Memior Amer. Math. Soc., 1991, 93:1-186.[6]Goodman, T. N. T., Lee, S. L., Convergence of cascade algorithms, in Mathematical Methods for Curves and Surfaces Ⅱ (eds. Daehlen, M., Lyche, T., Schumaker, L. L.) Nashville: Vanderbilt University Press, 1998,191-212.[7]Strang, G., Nguyen, T., Wavelets and Filter Banks, Boston: Wellesley-Cambride Press, 1996.[8]Dyn, N., Gregory, J. A., Levin, D., Analysis of uniform binary subdivision schemes for cure design, Constr.Approx., 1991, 23: 127-147.[9]Jia, R. Q., Subdivision schemes in Lp spaces, Advances in Comp. Math., 1995, 3: 309-341.[10]Han, B., Jia, R. Q., Multivariate refinement equations and convergence of subdivision schemes, SIAM J. Math.Anal., 1998, 29: 1177-1199.[11]Strang, G., Eigenvalues of (↓ 2)H and convergence of cascade algorithm, IEEE. Trans. SP, 1996, 44: 233-238.[12]Lawton, W., Lee, S. L., Shen, Z. W., Convergence of multidimensional cascade algorithms, Numer. Math.,1998, 78: 427-438.[13]Long, R. L., Mo, Q., L2-convergence of vector cascade algorithm, Approx. Theory Appl., 1999, 15: 24-49.[14]Shen, Z. W., Refinable function vectors, SIAM J. Math. Anal., 1998, 29: 235-250.[15]Zhou, D. X., Norms concerning subdivision sequences and their applications in wavelets, Applied and Computationic Harmonic Analysis, 2001, 11: 329

  4. Circulating and PBMC Lp-PLA2 associate differently with oxidative stress and subclinical inflammation in nonobese women (menopausal status.

    Directory of Open Access Journals (Sweden)

    Jean Kyung Paik

    Full Text Available BACKGROUND: This study aimed to determine the association of lipoprotein-associated phospholipase A(2 (Lp-PLA(2 activity in circulation and peripheral blood mononuclear cells (PBMCs with inflammatory and oxidative stress markers in nonobese women and according to menopausal status. Lp-PLA(2 activity, a marker for cardiovascular risk is associated with inflammation and oxidative stress. METHODOLOGY/PRINCIPAL FINDINGS: Eighty postmenopausal women (53.0±4.05 yr and 96 premenopausal women (39.7±9.25 yr participated in this study. Lp-PLA(2 activities, interleukin (IL-6, tumor necrosis factor (TNF-α, and IL-1β in plasma as well as in PBMCs were measured. Plasma ox-LDL was also measured. Postmenopausal women demonstrated higher circulating levels of ox-LDL and IL-6, as well as IL-6, TNF-α, and IL-1β in PBMCs, than premenopausal women. In both groups, plasma Lp-PLA(2 activity positively correlated with Lp-PLA(2 activity in PBMCs and plasma ox-LDL. In premenopausal women, Lp-PLA(2 activities in plasma and PBMCs positively correlated with IL-6, TNF-α, and IL-1β in PBMCs. In postmenopausal women, plasma ox-LDL positively correlated with PBMC cytokine production. In subgroup analysis of postmenopausal women according to plasma ox-LDL level (median level: 48.715 U/L, a significant increase in Lp-PLA(2 activity in the plasma but not the PBMCs was found in the high ox-LDL subgroup. Plasma Lp-PLA(2 activity positively correlated with unstimulated PBMC Lp-PLA(2 activity in the low ox-LDL subgroup (r = 0.627, P<0.001, whereas in the high ox-LDL circulating Lp-PLA(2 activity positively correlated with plasma ox-LDL (r = 0.390, P = 0.014 but not with Lp-PLA(2 activity in PBMCs. CONCLUSIONS/SIGNIFICANCE: The lack of relation between circulating Lp-PLA(2 activity and Lp-PLA(2 activity in PBMCs was found in postmenopausal women with high ox-LDL. This may indicate other sources of circulating Lp-PLA(2 activity except PBMC in postmenopausal women

  5. Lp stability for entropy solutions of scalar conservation laws with strict convex flux

    Science.gov (United States)

    Adimurthi; Ghoshal, Shyam Sundar; Veerappa Gowda, G. D.

    Here we consider the scalar convex conservation laws in one space dimension with strictly convex flux which is in C1. Existence, uniqueness and L1 contractivity were proved by Kružkov [14]. Using the relative entropy method, Leger showed that for a uniformly convex flux and for the shock wave solutions, the L2 norm of a perturbed solution relative to the shock wave is bounded by the L2 norm of the initial perturbation. Here we generalize the result to Lp norm for all 1⩽p<∞. Also we show that for the non-shock wave solution, Lp norm of the perturbed solution relative to the modified N-wave is bounded by the Lp norm of the initial perturbation for all 1⩽p<∞.

  6. Trellis-Based Check Node Processing for Low-Complexity Nonbinary LP Decoding

    CERN Document Server

    Punekar, Mayur

    2011-01-01

    Linear Programming (LP) decoding is emerging as an attractive alternative to decode Low-Density Parity-Check (LDPC) codes. However, the earliest LP decoders proposed for binary and nonbinary LDPC codes are not suitable for use at moderate and large code lengths. To overcome this problem, Vontobel et al. developed an iterative Low-Complexity LP (LCLP) decoding algorithm for binary LDPC codes. The variable and check node calculations of binary LCLP decoding algorithm are related to those of binary Belief Propagation (BP). The present authors generalized this work to derive an iterative LCLP decoding algorithm for nonbinary linear codes. Contrary to binary LCLP, the variable and check node calculations of this algorithm are in general different from that of nonbinary BP. The overall complexity of nonbinary LCLP decoding is linear in block length; however the complexity of its check node calculations is exponential in the check node degree. In this paper, we propose a modified BCJR algorithm for efficient check n...

  7. On the Analog of Shephard Problem for Lp-p olar Pro jection Bo dies

    Institute of Scientific and Technical Information of China (English)

    MA Tong-yi

    2015-01-01

    For p>0, Lutwak, Yang and Zhang introduced the concept of Lp-polar projection bodyΓ−pK of a convex body K in Rn. Let p≥1 and K, L⊂Rn be two origin-symmetric convex bodies, we consider the question of whetherΓ−p eK ⊂Γ−p eL impliesΩp(L)≤Ωp(K), where Ωp(K) denotes the Lp-affine surface area of K and eK = Voln(K)−1p K. We prove a necessary and sufficient condition of an analog of the Shephard problem for the Lp-polar projection bodies.

  8. Adaptively Active Contours Based on Variable Exponent Lp(|∇I| Norm for Image Segmentation

    Directory of Open Access Journals (Sweden)

    Wenying Wen

    2012-01-01

    Full Text Available We propose an Lp(|∇I|-based adaptively active contours model for image segmentation which is derived from the well-known Chan-Vese (C-V model. Unlike the C-V model, the proposed model uses the Lp(|∇I| (p(|∇I|>2 norm instead of the L2 norm to define the external energy and incorporates an extra internal energy into the overall energy. Due to the variable exponent p(|∇I|  which could fit the image gradient information adaptively, the proposed Lp(|∇I|-based model has the hope of segmenting those images with low contrast and blurred boundaries. Experimental results show that the proposed model with p(|∇I|>2 really can effectively and quickly segment those images with low contrast and blurred boundaries.

  9. Formalization and Parsing of Typed Unification-Based ID/LP Grammars

    CERN Document Server

    Morawietz, F

    1999-01-01

    This paper defines unification based ID/LP grammars based on typed feature structures as nonterminals and proposes a variant of Earley's algorithm to decide whether a given input sentence is a member of the language generated by a particular typed unification ID/LP grammar. A solution to the problem of the nonlocal flow of information in unification ID/LP grammars as discussed in Seiffert (1991) is incorporated into the algorithm. At the same time, it tries to connect this technical work with linguistics by presenting an example of the problem resulting from HPSG approaches to linguistics (Hinrichs and Nakasawa 1994, Richter and Sailer 1995) and with computational linguistics by drawing connections from this approach to systems implementing HPSG, especially the TROLL system, Gerdemann et al. (forthcoming).

  10. On the Busemann-Petty's Problem for Lp-intersection Body

    Institute of Scientific and Technical Information of China (English)

    MA Tong-yi

    2012-01-01

    Haberl and Ludwig introduced the Lp-intersection body IpK for an originsymmetric star body K in Rn,where p < 1 and p ≠ 0. In this paper,we consider the Busemann-Petty's problem for Lp-intersection bodies IpK and IpL.That is,whether Ip,K (C) IpL implies Voln(K) ≤ Voln(L).We obtain that for two origin-symmetric star bodies K and L in Rn,such that (Rn,||·|| K) embeds in L-p and IpK (C) IpL,then voln (K) ≤ voln (L)for 0 < p < 1 and voln(K) ≥ voln(L) for p < 0.

  11. Lp-gradient Estimates of Symmetric Markov Semigroups for 1 < p ≤ 2

    Institute of Scientific and Technical Information of China (English)

    Aha Bela CRUZEIRO; Xi Cheng ZHANG

    2006-01-01

    For 1 < p ≤ 2, an Lp-gradient estimate for a symmetric Markov semigroup is derived in application we prove that Γ1/2 ((I-L)-α) is a bounded operator from Lp to Lp provided that 1 < p < 2and 1/2 <α< 1. For any 1 < p < 2, q > 2 and 1/2 < c < 1, there exist two positive constants Cq,α,Cp,αsuch that ||Df||p ≤ Cp,α||(I - L)αf||p, Cq,α||(I - L)1-αf||q ≤ ||Df||q + ||f||q, where D is the Malliavin gradient ([2]) and L the Ornstein-Uhlenbeck operator.

  12. Defense and the Economy

    Science.gov (United States)

    1993-01-01

    AD A 66 28 o’py 9of 27 copiesII AD-A266 288-co, .o,,,, I IDA PAPER P-28 10I * DEFENSE AND THE ECONOMY David R. Graham An-Jen Tai Barbara A...TYPE AND DATES COVERED January 1993 4. TITLE AND SUBTITLE S. FUNDING NUMBERS Defense and the Economy C-MDA 903 89C 0003i...Fomr 298 (Rev 2-4g) 3Preserked by ANSI Sid, Z39- 2I0 I I I IDA PAPER P-2810() 3 DEFENSE AND THE ECONOMY I I David R. Graham An-Jen Tai Barbara A

  13. Effects of topography and crustal heterogeneities on the source estimation of LP event at Kilauea volcano

    Science.gov (United States)

    Cesca, S.; Battaglia, J.; Dahm, T.; Tessmer, E.; Heimann, S.; Okubo, P.

    2008-01-01

    The main goal of this study is to improve the modelling of the source mechanism associated with the generation of long period (LP) signals in volcanic areas. Our intent is to evaluate the effects that detailed structural features of the volcanic models play in the generation of LP signal and the consequent retrieval of LP source characteristics. In particular, effects associated with the presence of topography and crustal heterogeneities are here studied in detail. We focus our study on a LP event observed at Kilauea volcano, Hawaii, in 2001 May. A detailed analysis of this event and its source modelling is accompanied by a set of synthetic tests, which aim to evaluate the effects of topography and the presence of low velocity shallow layers in the source region. The forward problem of Green's function generation is solved numerically following a pseudo-spectral approach, assuming different 3-D models. The inversion is done in the frequency domain and the resulting source mechanism is represented by the sum of two time-dependent terms: a full moment tensor and a single force. Synthetic tests show how characteristic velocity structures, associated with shallow sources, may be partially responsible for the generation of the observed long-lasting ringing waveforms. When applying the inversion technique to Kilauea LP data set, inversions carried out for different crustal models led to very similar source geometries, indicating a subhorizontal cracks. On the other hand, the source time function and its duration are significantly different for different models. These results support the indication of a strong influence of crustal layering on the generation of the LP signal, while the assumption of homogeneous velocity model may bring to misleading results. ?? 2008 The Authors Journal compilation ?? 2008 RAS.

  14. 76 FR 49760 - Texas Eastern Transmission, LP; Notice of Application

    Science.gov (United States)

    2011-08-11

    ... section 7(b) of the Natural Gas Act (NGA) for authorization to abandon in place four reciprocating compressor units with a total of 4,400 horsepower and related appurtenances at Station No. 21-A of its Uniontown Compressor Station located in Fayette County, Pennsylvania. Texas Eastern states that there...

  15. L~p integrability of trigonometric series with special varying coefficients

    Institute of Scientific and Technical Information of China (English)

    WEI Bao-rong

    2009-01-01

    Very recently, Yu, Le and Zhou introduced the so called Δ_(B1)~* Δ_(B2)~* conditions,which are generalizations of the monotone condition. By applying these two new conditions,the author essentially generalizes the classical results of Chen on the necessary and sufficient conditions of the L~p integrability of trigonometric series. In fact, the present paper gives the first result on the necessary and sufficient conditions of the L~p integrability of trigonometric series, where coefficients may have different signs.

  16. 黑白煞 兰博基尼Hamann Murcielago LP640

    Institute of Scientific and Technical Information of China (English)

    Ric

    2007-01-01

    哈曼(HAMANN)为了证明兰博基尼蝙蝠(Murcielago)LP640的实力,对其外观造型,驾驶动力以及声音进行重新设定。哈曼为其配备了前扰流器,增添了尾翼,还有两片式尾部扩散板且带有额外的导气管,给车前后端带来了更大的下压力,使LP640更具流线造型。

  17. 最猛蛮牛兰博基尼Murcielago LP 670-4 Super Veloce

    Institute of Scientific and Technical Information of China (English)

    周志华

    2010-01-01

    兰博基尼作为一个不服气而诞生的品牌,它的顶级车型倍受车迷狂热者追捧,并一直与时俱进地进行着翻新。说到如今最猛的车型,则非这款Murcielago LP 670-4SuperVeloce莫属,它在动力、重量和速度方面都比Murcielago LP 640更胜一筹

  18. Survey on Legionella serotypes antibody levels of Lp1 ~ Lp10, Lm, and Lb of part of Shijiazhuang population%石家庄市部分人群血清军团菌Lp1~Lp10和Lm、Lb型抗体水平调查

    Institute of Scientific and Technical Information of China (English)

    李波; 李明英; 刘书强; 王春妍; 魏秀萍; 剧惠栋; 秦丽云

    2011-01-01

    Objective To leant the distribution characteristics and dominant species of Legionella infection type in Shijiazhuang. Method Adopting microagglutination test to detect the antibody titer of Lpl - Lp10, Lm, and Lb - type in serum of 216 healthy volunteers. Results Various antibody types of Legionella had detected out positive samples except Lp2. The positive rate of Legionella antibody in healthy population was 43.98% (95/216) , while 25.26% of population were infected with 2 or 3 positive type. In healthy population, the infection rate of Lp9 was the highest ( 23.43% ) , followed by Lb (22.73% ) and Lm ( 12.5% ) types. Conclusions Different types of Legionella infection were ubiquity in Shijiazhuang, so relevant departments must pay attention to Legionella diagnose and treatment, and enhance the monitoring level of it.%目的 了解石家庄市军团菌感染种型分布特点和优势种型.方法 采用微量凝集试验对216名健康体检人员血清标本进行Lp1~Lp10和Lm、Lb型抗体效价测定.结果 所测军团菌各种型除Lp2型未检出阳性个体外,其余各型均有阳性检出,健康人群军团菌阳性率为43.98% (95/216),同时感染2~3种血清型者占25.26%.健康人Lp9型阳性率最高(23.43%),其次为Lb (22.73%)、Lm (12.5%),Lp2型未检出阳性.结论 石家庄市普遍存在不同种型的军团菌感染,军团菌的诊疗和监测水平的提高应引起有关部门的重视.

  19. Long Period (LP) volcanic earthquake source location at Merapi volcano by using dense array technics

    Science.gov (United States)

    Metaxian, Jean Philippe; Budi Santoso, Agus; Laurin, Antoine; Subandriyo, Subandriyo; Widyoyudo, Wiku; Arshab, Ghofar

    2015-04-01

    Since 2010, Merapi shows unusual activity compared to last decades. Powerful phreatic explosions are observed; some of them are preceded by LP signals. In the literature, LP seismicity is thought to be originated within the fluid, and therefore to be representative of the pressurization state of the volcano plumbing system. Another model suggests that LP events are caused by slow, quasi-brittle, low stress-drop failure driven by transient upper-edifice deformations. Knowledge of the spatial distribution of LP events is fundamental for better understanding the physical processes occurring in the conduit, as well as for the monitoring and the improvement of eruption forecasting. LP events recorded at Merapi have a spectral content dominated by frequencies between 0.8 and 3 Hz. To locate the source of these events, we installed a seismic antenna composed of 4 broadband CMG-6TD Güralp stations. This network has an aperture of 300 m. It is located on the site of Pasarbubar, between 500 and 800 m from the crater rim. Two multi-parameter stations (seismic, tiltmeter, S-P) located in the same area, equipped with broadband CMG-40T Güralp sensors may also be used to complete the data of the antenna. The source of LP events is located by using different approaches. In the first one, we used a method based on the measurement of the time delays between the early beginnings of LP events for each array receiver. The observed differences of time delays obtained for each pair of receivers are compared to theoretical values calculated from the travel times computed between grid nodes, which are positioned in the structure, and each receiver. In a second approach, we estimate the slowness vector by using MUSIC algorithm applied to 3-components data. From the slowness vector, we deduce the back-azimuth and the incident angle, which give an estimation of LP source depth in the conduit. This work is part of the Domerapi project funded by French Agence Nationale de la Recherche (https

  20. Broadband electric-field-induced LP01 and LP02 second harmonic generation in Xe-filled hollow-core PCF.

    Science.gov (United States)

    Ménard, Jean-Michel; Köttig, Felix; St J Russell, Philip

    2016-08-15

    Second harmonic (SH) generation with 300 fs pump pulses is reported in a xenon-filled hollow-core photonic crystal fiber (PCF) across which an external bias voltage is applied. Phase-matched intermodal conversion from a pump light in the LP01 mode to SH light in the LP02 mode is achieved at a particular gas pressure. Using periodic electrodes, quasi-phase-matched SH generation into the low-loss LP01 mode is achieved at a different pressure. The low linear dispersion of the gas enables phase-matching over a broad spectral window, resulting in a measured bandwidth of ∼10  nm at high pump energies. A conversion efficiency of ∼18%/mJ is obtained. Gas-filled anti-resonant-reflecting hollow-core PCF uniquely offers pressure-tunable phase-matching, ultra-broadband guidance, and a very high optical damage threshold, which hold great promise for efficient three-wave mixing, especially in difficult-to-access regions of the electromagnetic spectrum.

  1. 78 FR 22765 - Presidential Determination on Eligibility of the Federal Republic of Somalia To Receive Defense...

    Science.gov (United States)

    2013-04-16

    ... Federal Register. (Presidential Sig.) THE WHITE HOUSE, Washington, April 8, 2013 [FR Doc. 2013-09106 Filed... Eligibility of the Federal Republic of Somalia To Receive Defense Articles and Defense Services Under the... defense services to the Federal Republic of Somalia will strengthen the security of the United States...

  2. A spinach O-acetylserine(thiollyase homologue, SoCSaseLP, suppresses cysteine biosynthesis catalysed by other enzyme isoforms

    Directory of Open Access Journals (Sweden)

    Miki Noda

    2016-06-01

    Full Text Available An enzyme, O-acetylserine(thiollyase (OASTL, also known as O-acetylserine sulfhydrylase or cysteine synthase (CSase, catalyses the incorporation of sulfide into O-acetylserine and produces cysteine. We previously identified a cDNA encoding an OASTL-like protein from Spinacia oleracea, (SoCSaseLP, but a recombinant SoCSaseLP produced in Escherichia coli did not show OASTL activity. The exon-intron structure of the SoCSaseLP gene shared conserved structures with other spinach OASTL genes. The SoCSaseLP and a Beta vulgaris homologue protein, KMT13462, comprise a unique clade in the phylogenetic tree of the OASTL family. Interestingly, when the SoCSaseLP gene was expressed in tobacco plants, total OASTL activity in tobacco leaves was reduced. This reduction in total OASTL activity was most likely caused by interference by SoCSaseLP with cytosolic OASTL. To investigate the possible interaction of SoCSaseLP with a spinach cytosolic OASTL isoform SoCSaseA, a pull-down assay was carried out. The recombinant glutathione S-transferase (GST-SoCSaseLP fusion protein was expressed in E. coli together with the histidine-tagged SoCSaseA protein, and the protein extract was subjected to glutathione affinity chromatography. The histidine-tagged SoCSaseA was co-purified with the GST-SoCSaseLP fusion protein, indicating the binding of SoCSaseLP to SoCSaseA. Consistent with this interaction, the OASTL activity of the co-purified SoCSaseA was reduced compared with the activity of SoCSaseA that was purified on its own. These results strongly suggest that SoCSaseLP negatively regulates the activity of other cytosolic OASTL family members by direct interaction.

  3. Association of carotid plaque Lp-PLA(2 with macrophages and Chlamydia pneumoniae infection among patients at risk for stroke.

    Directory of Open Access Journals (Sweden)

    Berna Atik

    Full Text Available BACKGROUND: We previously showed that the burden of Chlamydia pneumoniae in carotid plaques was significantly associated with plaque interleukin (IL-6, and serum IL-6 and C-reactive protein (CRP, suggesting that infected plaques contribute to systemic inflammatory markers in patients with stroke risk. Since lipoprotein-associated phospholipase A2 (Lp-PLA(2 mediates inflammation in atherosclerosis, we hypothesized that serum Lp-PLA(2 mass and activity levels and plaque Lp-PLA(2 may be influenced by plaque C. pneumoniae infection. METHODOLOGY/PRINCIPAL FINDINGS: Forty-two patients underwent elective carotid endarterectomy. Tissue obtained at surgery was stained by immunohistochemistry for Lp-PLA(2 grade, macrophages, IL-6, C. pneumoniae and CD4+ and CD8+ cells. Serum Lp-PLA(2 activity and mass were measured using the colorimetric activity method (CAM and ELISA, respectively. Serum homocysteine levels were measured by HPLC. Eleven (26.2% patients were symptomatic with transient ischemic attacks. There was no correlation between patient risk factors (smoking, coronary artery disease, elevated cholesterol, diabetes, obesity, hypertension and family history of genetic disorders for atherosclerosis and serum levels or plaque grade for Lp-PLA(2. Plaque Lp-PLA(2 correlated with serum homocysteine levels (p = 0.013, plaque macrophages (p<0.01, and plaque C. pneumoniae (p<0.001, which predominantly infected macrophages, co-localizing with Lp-PLA(2. CONCLUSIONS: The significant association of plaque Lp-PLA(2 with plaque macrophages and C. pneumoniae suggests an interactive role in accelerating inflammation in atherosclerosis. A possible mechanism for C. pneumoniae in the atherogenic process may involve infection of macrophages that induce Lp-PLA(2 production leading to upregulation of inflammatory mediators in plaque tissue. Additional in vitro and in vivo research will be needed to advance our understanding of specific C. pneumoniae and Lp-PLA(2

  4. Rethinking Defensive Information Warfare

    Science.gov (United States)

    2004-06-01

    electronic warfare, and special information operations. Defensive information operations ensure timely, accurate, and relevant information access...information and information systems. IA, physical security, OPSEC, counter-deception, counter-psyops, CI, EW, and special information operations. Ensure

  5. A Note on Linearly Isometric Extension for 1-Lipschitz and Anti-1-Lipschitz Mappings between Unit Spheres of ALp(μ, H) Spaces

    Institute of Scientific and Technical Information of China (English)

    Zihou ZHANG; Chunyan LIU

    2013-01-01

    In this paper,we show that if V0 is a 1-Lipschitz mapping between unit spheres of Lp (μ,H) and Lp(v,H)(p > 2,H is a Hilbert space),and-Vo(S(Lp(μ,H))) (∪) Vo(S(Lp(μ,H))),then V0 can be extended to a linear isometry defined on the whole space.If 1 < p < 2 and V0 is an "anti-1-Lipschitz" mapping,then Vo can also be linearly and isometrically extended.

  6. 75 FR 76423 - Defense Intelligence Agency National Defense Intelligence College Board of Visitors Closed Meeting

    Science.gov (United States)

    2010-12-08

    ... of the Secretary Defense Intelligence Agency National Defense Intelligence College Board of Visitors Closed Meeting AGENCY: National Defense Intelligence College, Defense Intelligence Agency, Department of... a closed meeting of the Defense Intelligence Agency National Defense Intelligence College Board...

  7. 76 FR 28960 - Defense Intelligence Agency National Defense Intelligence College Board of Visitors Closed Meeting

    Science.gov (United States)

    2011-05-19

    ... of the Secretary Defense Intelligence Agency National Defense Intelligence College Board of Visitors Closed Meeting AGENCY: National Defense Intelligence College, Defense Intelligence Agency, Department of... a closed meeting of the Defense Intelligence Agency National Defense Intelligence College Board...

  8. 76 FR 28757 - Defense Logistics Agency Revised Regulation 1000.22, Environmental Considerations in Defense...

    Science.gov (United States)

    2011-05-18

    ... of the Secretary Defense Logistics Agency Revised Regulation 1000.22, Environmental Considerations in Defense Logistics Agency Actions AGENCY: Defense Logistics Agency, Department of Defense. ACTION: Notice of Availability (NOA) of Revised Defense Logistics Agency Regulation. SUMMARY: The Defense Logistics...

  9. Development and Application of LP-ⅠParaffin Remover/Inhibitor%LP-Ⅰ清防蜡剂的研制及应用

    Institute of Scientific and Technical Information of China (English)

    刘翩翩; 刘磊; 张磬文; 齐从温; 舒福昌

    2014-01-01

    In order to solve the serious problem of paraffin deposit at Yuan 300 and Yuan 301 area in Chan-gqing Oilfield,based on melting point,composition,gas chromatography and infrared analysis,paraffin remover and paraffin inhibitor were screened and optimized,and LP-Ⅰparaffin remover/inhibitor was developed.Results showed that,paraffin removal rate of paraffin remover which complexed with petroleum ether,xylene,cyclohex-ane,kerosene and additives for paraffin remover/inhibitor was 96.23%;paraffin inhibition rate of paraffin inhib-itor which complexed with naphthalene,sodium petroleum sulfonate and high-pressure polyethylene was 32.47%;paraffin removal rate and paraffin inhibition rate of paraffin remover/inhibitor complexed with paraffin remover and paraffin inhibitor of 2∶1 were 85.23%,27.59%,respectively.The field test results showed that, adding LP-Ⅰ paraffin remover/inhibitor into Yuan 301-56 and Yuan 301-39,their maxium load reduced,minium load increased,area of loading curve reduced obviously,wax didn′t appear.Above results indicated that LP-Ⅰparaffin remover/inhibitor had good application efficiency.%为解决长庆油田元300和元301区油井严重结蜡的问题,在对该地区蜡样的熔点、组分、气相色谱和红外光谱进行分析的基础上,优化筛选了清蜡剂和防蜡剂,研制了适合长庆油田区块的 LP-Ⅰ清防蜡剂。结果表明:以石油醚、二甲苯、环己烷、煤油与一定量清防蜡剂助剂复配得到的清蜡剂的清蜡率为96.23%;以萘、石油磺酸钠与高压聚乙烯复配得到的防蜡剂的防蜡率为32.47%;以清蜡剂∶防蜡剂=2∶1的比例复配得到 LP-Ⅰ清防蜡剂的清蜡率为85.23%、防蜡率为27.59%。现场试验结果表明,添加 LP-Ⅰ清防蜡剂的元301-56井和元301-59井示功图的最高载荷下降,最低载荷略有上升,载荷曲线面积明显变小,未出现明显结蜡现象,表明 LP-Ⅰ清防蜡剂现场应用效果良好。

  10. Strategic defense and the Western alliance

    Energy Technology Data Exchange (ETDEWEB)

    Lakoff, S.; Willoughby, R. (Univ. of California, CA (US))

    1987-01-01

    Strategic defense has again become a major item on the agenda of the Western Alliance. Revived by President Ronald Reagan in his Star Wars speech of March 1983, and implemented in his Strategic Defense Initiative, it has achieved renewed emphasis in military spending, in alliance research efforts, and in arms control negotiations. SDI is packaged in a way that makes it the largest single item in the Department of Defense's annual budget. It engages researchers in industrial and military laboratories on both sides of the Atlantic as well as in Japan and Israel. In the arms control negotiations now under way between the United States and the USSR, the conduct of this research and its implications for the strategic balance and the reduction of offensive weapons are critical considerations. The implications of this largely unexpected development are the subject of this book.

  11. 75 FR 51451 - Erie Boulevard Hydropower, L.P.; Notice of Intent To File License Application, Filing of Pre...

    Science.gov (United States)

    2010-08-20

    ... Energy Regulatory Commission Erie Boulevard Hydropower, L.P.; Notice of Intent To File License..., 2010. d. Submitted By: Erie Boulevard Hydropower, L.P. e. Name of Project: Chasm Hydroelectric Project... project works or located within the project boundary. g. Filed Pursuant to: 18 CFR 5.3 of the Commission's...

  12. 78 FR 68044 - Erie Boulevard Hydropower, L.P.; Notice of Scoping Meetings and Environmental Site Review and...

    Science.gov (United States)

    2013-11-13

    ... Energy Regulatory Commission Erie Boulevard Hydropower, L.P.; Notice of Scoping Meetings and... Boulevard Hydropower, L.P. e. Name of Project: Chasm Hydroelectric Project. f. Location: On the Salmon River, in Franklin County, New York. No federal lands are occupied by the project works or located within...

  13. 76 FR 66710 - Erie Boulevard Hydropower, L.P.; Notice of Application Accepted for Filing, Soliciting Comments...

    Science.gov (United States)

    2011-10-27

    ... Energy Regulatory Commission Erie Boulevard Hydropower, L.P.; Notice of Application Accepted for Filing...: Erie Boulevard Hydropower, L.P. (dba Brookfield Renewable Power). e. Name of Projects: Oswego Falls... works which are the subject of the license surrender. Agencies may obtain copies of the application...

  14. 78 FR 43188 - Erie Boulevard Hydropower, L.P.; Notice of Application Tendered for Filing With the Commission...

    Science.gov (United States)

    2013-07-19

    ... Energy Regulatory Commission Erie Boulevard Hydropower, L.P.; Notice of Application Tendered for Filing... Hydropower, L.P. e. Name of Project: Chasm Hydroelectric Project. f. Location: On the Salmon River, in Franklin County, New York. No federal lands are occupied by the project works or located within the project...

  15. 78 FR 62348 - Erie Boulevard Hydropower, L.P.; Notice of Application Accepted for Filing and Soliciting Motions...

    Science.gov (United States)

    2013-10-18

    ... Energy Regulatory Commission Erie Boulevard Hydropower, L.P.; Notice of Application Accepted for Filing... Hydropower, L.P. e. Name of Project: Chasm Hydroelectric Project. f. Location: On the Salmon River, in Franklin County, New York. No federal lands are occupied by the project works or located within the project...

  16. 75 FR 64306 - Shell Energy North America (US), LP; Notice of Institution of Proceeding and Refund Effective Date

    Science.gov (United States)

    2010-10-19

    ... Energy Regulatory Commission Shell Energy North America (US), LP; Notice of Institution of Proceeding and... U.S.C. 824e (2005), concerning the justness and reasonableness of Shell Energy North America (US), LP's market- based rate authority in the Central and Southwest balancing authority area. Shell...

  17. 78 FR 25432 - Sabine Pass LNG, L.P., Sabine Pass Liquefaction, LLC; Notice of Availability of the Environmental...

    Science.gov (United States)

    2013-05-01

    ... Energy Regulatory Commission Sabine Pass LNG, L.P., Sabine Pass Liquefaction, LLC; Notice of Availability... Sabine Pass Sabine Pass LNG, L.P. and Sabine Pass Liquefaction, LLC (Sabine Pass) in the above-referenced... construction at the existing Sabine Pass LNG terminal in Cameron Parish, Louisiana. The EA assesses...

  18. 76 FR 9573 - Sabine Pass Liquefaction, LLC and Sabine Pass LNG, L.P.; Notice of Application

    Science.gov (United States)

    2011-02-18

    ... Energy Regulatory Commission Sabine Pass Liquefaction, LLC and Sabine Pass LNG, L.P.; Notice of Application Take notice that on January 31, 2011, Sabine Pass Liquefaction, LLC and Sabine Pass LNG, L.P... (Liquefaction Project) at the existing Sabine Pass LNG Terminal, located in Cameron Parish, Louisiana....

  19. 75 FR 13755 - Freeport LNG Development, L.P.; Application To Amend Blanket Authorization To Export Liquefied...

    Science.gov (United States)

    2010-03-23

    ... Freeport LNG Development, L.P.; Application To Amend Blanket Authorization To Export Liquefied Natural Gas... application filed on March 4, 2010, by Freeport LNG Development, L.P. (Freeport LNG), requesting an amendment to its blanket authorization to export liquefied natural gas (LNG) granted by DOE/FE on May 28,...

  20. 76 FR 76698 - Dominion Cove Point LNG, LP; Application To Export Domestic Liquefied Natural Gas to Non-Free...

    Science.gov (United States)

    2011-12-08

    ...] [FR Doc No: 2011-31518] DEPARTMENT OF ENERGY [FE Docket No. 11-128-LNG] Dominion Cove Point LNG, LP..., by Dominion Cove Point LNG, LP (DCP), requesting long- term, multi-contract authorization to export up to 7.82 million metric tons per year of domestically produced liquefied natural gas...

  1. 77 FR 59601 - Dominion Cove Point LNG, LP; Notice of Intent To Prepare an Environmental Assessment for the...

    Science.gov (United States)

    2012-09-28

    ... Energy Regulatory Commission Dominion Cove Point LNG, LP; Notice of Intent To Prepare an Environmental... and operation of facilities by Dominion Cove Point LNG, LP (Dominion) in Maryland and Virginia. This... 717b, DOE would authorize the export of natural gas, including liquefied natural gas (LNG),...

  2. 75 FR 6414 - Cardinal Growth, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business...

    Science.gov (United States)

    2010-02-09

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Cardinal Growth, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment... Business Administration (``SBA'') Rules and Regulations (13 CFR 107.730). Cardinal Growth, L.P....

  3. 78 FR 4842 - Linden VFT, LLC v. Brookfield Energy Marketing, LP, Cargill Power Markets, LLC; Notice of Complaint

    Science.gov (United States)

    2013-01-23

    ... Energy Regulatory Commission Linden VFT, LLC v. Brookfield Energy Marketing, LP, Cargill Power Markets... a formal complaint against Brookfield Energy Marketing, LP and Cargill Power Markets, LLC...., Washington, DC 20426. This filing is accessible on-line at http://www.ferc.gov , using the ``eLibrary'' link...

  4. 75 FR 56093 - Eagle Rock Desoto Pipeline, LP; Notice of Motion for Extension of Rate Case Filing Deadline

    Science.gov (United States)

    2010-09-15

    ... Energy Regulatory Commission Eagle Rock Desoto Pipeline, LP; Notice of Motion for Extension of Rate Case Filing Deadline September 8, 2010. Take notice that on September 8, 2010, Eagle Rock Desoto Pipeline, L.P. (Eagle Rock) filed a request to extend the date for filing its next rate case to May 1, 2012. Eagle...

  5. 76 FR 15306 - Aspen Merchant Energy LP; Supplemental Notice That Initial Market-Based Rate Filing Includes...

    Science.gov (United States)

    2011-03-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Aspen Merchant Energy LP; Supplemental Notice That Initial Market-Based Rate...-referenced proceeding of Aspen Merchant Energy LP's application for market-based rate authority, with...

  6. 77 FR 42353 - Escalate Capital Partners SBIC I, L.P.; Notice Seeking Exemption Under Section 312 of the Small...

    Science.gov (United States)

    2012-07-18

    ... ADMINISTRATION Escalate Capital Partners SBIC I, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Escalate Capital Partners SBIC I...). Escalate Capital Partners SBIC I, L.P. proposes to make a debt investment in Mavenir Systems, Inc.,...

  7. 75 FR 3502 - KLH Capital, L.P.; Notice Seeking Exemption Under 312 of the Small Business Investment Act...

    Science.gov (United States)

    2010-01-21

    ... ADMINISTRATION KLH Capital, L.P.; Notice Seeking Exemption Under 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that KLH Capital, L.P., 101 East Kennedy Boulevard, Suite 3925, Tampa, Florida 33602, a Federal Licensee under the Small Business Investment Act of 1958, as...

  8. 76 FR 17180 - KLH Capital II, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment...

    Science.gov (United States)

    2011-03-28

    ... ADMINISTRATION KLH Capital II, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that KLH Capital, L.P., 101 East Kennedy Boulevard, Suite 3925, Tampa, FL, 33602 a Federal Licensee under the Small Business Investment Act of 1958,...

  9. 77 FR 65546 - Sabine Pass Liquefaction, LLC; Sabine Pass LNG, L.P.; Notice of Petition To Amend Authorizations...

    Science.gov (United States)

    2012-10-29

    ... Energy Regulatory Commission Sabine Pass Liquefaction, LLC; Sabine Pass LNG, L.P.; Notice of Petition To... Pass Liquefaction, LLC and Sabine Pass LNG, L.P. (collectively, Sabine Pass), 700 Milam Street, Suite... and operate certain related facilities (Modification Project) at the existing Sabine Pass LNG...

  10. 78 FR 66909 - Sabine Pass Liquefaction, LLC; Sabine Pass LNG, L.P.; Notice of Application to Amend...

    Science.gov (United States)

    2013-11-07

    ... Energy Regulatory Commission Sabine Pass Liquefaction, LLC; Sabine Pass LNG, L.P.; Notice of Application... Sabine Pass Liquefaction, LLC and Sabine Pass LNG, L.P. (collectively, Sabine Pass), 700 Milam Street...,006 Bcf per year). Sabine Pass' requested increase in authorized capacity is an increase from...

  11. Unge indvandrere på kontanthjælp i Københavns kommune: Barrierer for uddannelse og arbejde

    DEFF Research Database (Denmark)

    Pico Geerdsen, Lars; Jakobsen, Vibeke

    I dette arbejdspapir undersøges, hvilke barrierer for uddannelse og beskæftigelse, der eksisterer for unge indvandrere på kontanthjælp i Københavns Kommune. I undersøgelsen gives en karakteristik af de unge indvandrere på kontanthjælp. Desuden analyseres deres kontakt med aktiveringssystemet og e...

  12. 75 FR 39244 - Arizona Public Service Company, Sequent Energy Management, L.P.; Notice of Joint Petition for...

    Science.gov (United States)

    2010-07-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Arizona Public Service Company, Sequent Energy Management, L.P.; Notice of... notice that on June 25, 2010, Arizona Public Service Company and Sequent Energy Management, L.P....

  13. 75 FR 32230 - Solutions Capital I, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business...

    Science.gov (United States)

    2010-06-07

    ... ADMINISTRATION Solutions Capital I, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Solutions Capital I, L.P., 1100 Wilson Blvd... Small Business Administration (``SBA'') Rules and Regulations (13 CFR 107.730). Solutions Capital I,...

  14. 77 FR 30002 - Regency Field Services LLC, v. DCP Black Lake Pipe Holdings, LP; Notice of Complaint

    Science.gov (United States)

    2012-05-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Regency Field Services LLC, v. DCP Black Lake Pipe Holdings, LP; Notice of... a complaint against DCP Black Lake Pipe Holdings, LP (Black Lake or Respondent) alleging that...

  15. 78 FR 47313 - DCP Midstream, LP; Notice of Intent To Prepare an Environmental Assessment for the Proposed...

    Science.gov (United States)

    2013-08-05

    ... Energy Regulatory Commission DCP Midstream, LP; Notice of Intent To Prepare an Environmental Assessment... construction and operation of facilities by DCP Midstream, LP (DCP) in Weld County, Colorado. The Commission... accordance with state law. DCP provided landowners with a fact sheet prepared by the FERC entitled...

  16. 76 FR 70717 - DCP Midstream, LP; Notice of Intent To Prepare an Environmental Assessment for the Proposed...

    Science.gov (United States)

    2011-11-15

    ... Energy Regulatory Commission DCP Midstream, LP; Notice of Intent To Prepare an Environmental Assessment... construction and operation of facilities by DCP Midstream, LP (DCP) in Weld County, Colorado. This EA will be... Do I Need To Know?'' was attached to the project notice DCP provided to landowners. This fact...

  17. Lipoprotein-associated phospholipase A2 (Lp-PLA(2)): a novel and promising biomarker for cardiovascular risks assessment.

    Science.gov (United States)

    Cai, Anping; Zheng, Dongdan; Qiu, Ruofeng; Mai, Weiyi; Zhou, Yingling

    2013-01-01

    Atherosclerosis and its manifestations namely cardiovascular diseases (CVD) are still the leading cause of morbidity and mortality worldwide. Although intensified interventions have been applied, the residual cardiovascular (CV) risks are still very high. Lipoprotein-associated phospholipase A2 (Lp-PLA(2)) is a novel and unique biomarker highly specific for vascular inflammation and atherosclerosis. Both pro-atherogenic property of Lp-PLA(2) and positive correlation with CV events have already been demonstrated by a large number of scientific and clinical studies. Currently, in the Adult Treatment Panel III (ATP III) guideline, Lp-PLA(2) has been recommended as an adjunct to traditional risk factors in assessing future CV risks. Encouragingly, darapladib, an orally Lp-PLA(2) specific inhibitor, has been tested in basic research and preclinical trials and the outcomes are quite striking. Additionally, there are two phase III ongoing clinical trials in evaluating the efficacy and safety of darapladib on cardiovascular outcomes. With regard to the potential values of Lp-PLA(2) in risk stratification, therapeutic regimen establishment and prognosis evaluation in patients with moderate or high risk, our present review is going to summarize the relevant data about the bio-chemical characteristics of Lp-PLA(2), the actions of Lp-PLA(2) on atherosclerosis and the results of Lp-PLA(2) in scientific research and clinical studies.

  18. 77 FR 52018 - Oxy Midstream Strategic Development, LLC, Magellan Midstream Partners, L.P.; Notice of Petition...

    Science.gov (United States)

    2012-08-28

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Oxy Midstream Strategic Development, LLC, Magellan Midstream Partners, L.P... Strategic Development, LLC and Magellan Midstream Partners, L.P., on behalf of BridgeTex Pipeline...

  19. Differential scanning calorimetry approach to investigate the transfer of the multitarget opioid analgesic LP1 to biomembrane model.

    Science.gov (United States)

    Accolla, Maria Lorena; Turnaturi, Rita; Sarpietro, Maria Grazia; Ronsisvalle, Simone; Castelli, Francesco; Pasquinucci, Lorella

    2014-04-22

    An emerging approach in pain management is the use of multitarget opioid ligands, owing an improved analgesic effect coupled to a reduced incidence of side effects. With a mu opioid receptor agonist/delta opioid receptor antagonist profile, the benzomorphan-based compound LP1 belongs to multitarget ligands class. Previous in vivo investigations showed that LP1 - subcutaneously administered as oxalate salt - was an antinociceptive agent as potent as morphine with a low tolerance-inducing capability. Because the renal toxicity of oxalate is known, an alternative approach allowing the administration of LP1 freebase could be more biocompatible. In this study the interaction of LP1 freebase and LP1 oxalate salt with multilamellar vesicles, as membrane model, was evaluated using differential scanning calorimetry technique. Despite the good membrane interaction showed by LP1 freebase, it was not capable to diffuse in the aqueous medium and to be uptaken by multilamellar vesicles. On the other hand, LP1 freebase possessed a good transfer profile by a liposomal carrier to a biomembrane model. Considering our findings and the need of safe formulations, studies for the development of a suitable carrier for a systemic administration of LP1 freebase are in progress. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  20. The lysine-peptoid hybrid LP5 maintain activity under physiological conditions and affects virulence gene expression in Staphylococcus aureus

    DEFF Research Database (Denmark)

    Gottschalk, Sanne; Ingmer, Hanne; Thomsen, Line E.

    2016-01-01

    , we found that LP5 was protease resistant. However, the dltA and vraF genes, involved in reducing the net anionic charge of the bacterial cell envelope and sensing of antimicrobial peptides, respectively, played a role in the tolerance of S. aureus against LP5. In addition, the exposure of S. aureus...

  1. 76 FR 77580 - Contemporary Healthcare Senior Lien Fund I, LP; Notice Seeking Exemption Under Section 312 of the...

    Science.gov (United States)

    2011-12-13

    ... ADMINISTRATION Contemporary Healthcare Senior Lien Fund I, LP; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Contemporary Healthcare... CFR 107.730). Contemporary Healthcare Senior Lien Fund I, LP, proposes to provide a loan to New...

  2. Defense Enterprise Accounting and Management System-Increment 1 (DEAMS Inc 1)

    Science.gov (United States)

    2016-03-01

    2016 Major Automated Information System Annual Report Defense Enterprise Accounting and Management System-Increment 1 (DEAMS Inc 1) Defense...Phone: 937-257-2714 Fax: DSN Phone: 787-2714 DSN Fax: Date Assigned: August 17, 2015 Program Information Program Name Defense Enterprise Accounting ...UNCLASSIFIED 4 Program Description The Defense Enterprise Accounting and Management System (DEAMS) is a key part of the United States Air Force (USAF

  3. The elevation of apoB in hypercholesterolemic patients is primarily attributed to the relative increase of apoB/Lp-PLA₂.

    Science.gov (United States)

    Tellis, Constantinos C; Moutzouri, Eliza; Elisaf, Moses; Wolfert, Robert L; Tselepis, Alexandros D

    2013-12-01

    Lipoprotein-associated phospholipase A₂ (Lp-PLA₂) is a risk factor of cardiovascular disease. Plasma Lp-PLA₂ is mainly associated with apolipoprotein (apo)B-containing lipoproteins, primarily with low density lipoproteins (LDLs). Importantly, only a proportion of circulating lipoproteins contain Lp-PLA₂. We determined the plasma levels of Lp-PLA₂-bound apoB (apoB/Lp-PLA₂) in patients with primary hypercholesterolemia. The effect of simvastatin therapy was also addressed. The plasma apoB/Lp-PLA₂ concentration in 50 normolipidemic controls and 53 patients with primary hypercholesterolemia at baseline and at 3 months posttreatment with simvastatin (40 mg/day) was determined by an enzyme-linked immunosorbent assay. The concentration of the apoB-containing lipoproteins that do not bind Lp-PLA₂ [apoB/Lp-PLA₂⁻] was calculated by subtracting the apoB/Lp-PLA₂ from total apoB. The apoB/Lp-PLA₂ levels were 3.6-fold higher, while apoB/Lp-PLA₂⁻ were 1.3-fold higher in patients compared with controls. After 3 months of simvastatin treatment apoB/Lp-PLA₂ and apoB/Lp-PLA₂⁻ levels were reduced by 52% and 33%, respectively. The elevation in apoB-containing lipoproteins in hypercholesterolemic patients is mainly attributed to the relative increase in the proatherogenic apoB/Lp-PLA₂, while simvastatin reduces these particles to a higher extent compared with apoB/Lp-PLA₂⁻. Considering that Lp-PLA₂ is proatherogenic, the predominance of apoB/Lp-PLA₂ particles in hypercholesterolemic patients may contribute to their higher atherogenicity and incidence of cardiovascular disease.

  4. On the Integrality Gap of the Subtour LP for the 1,2-TSP

    CERN Document Server

    Qian, Jiawei; Williamson, David P; van Zuylen, Anke

    2011-01-01

    In this paper, we study the integrality gap of the subtour LP relaxation for the traveling salesman problem in the special case when all edge costs are either 1 or 2. For the general case of symmetric costs that obey triangle inequality, a famous conjecture is that the integrality gap is 4/3. Little progress towards resolving this conjecture has been made in thirty years. For the case when all edge costs $c(i,j)\\in\\{1,2\\}$, we can show that the integrality gap is at most $106/81 \\approx 1.31 < 4/3$; this is the first bound on the integrality gap of the subtour LP strictly less than 4/3 known for an interesting special case of the TSP. In the case the solution to the subtour LP is a fractional 2-matching, we can show that the gap is at most 7/6; if the solution to the subtour LP is a unique fractional 2-matching, we can show that the gap is at most 10/9, and this is tight. We also perform computational experiments that show that the gap is at most 10/9 for $n \\leq 10$.

  5. 77 FR 71585 - Brookfield Energy Marketing LP v. ISO New England Inc.; Notice of Complaint

    Science.gov (United States)

    2012-12-03

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Brookfield Energy Marketing LP v. ISO New England Inc.; Notice of...) filed a formal complaint against ISO New England Inc. (Respondent) alleging that the...

  6. Efficacy and safety of the probiotic Lactobacillus paracasei LP-33 in allergic rhinitis

    DEFF Research Database (Denmark)

    Costa, D J; Marteau, P; Amouyal, M

    2014-01-01

    BACKGROUND/OBJECTIVES: An imbalance between Th1 and Th2 cells is involved in allergic rhinitis (AR) that may be improved by probiotics. To test the efficacy of the probiotic Lactobacillus paracasei subsp. paracasei LP-33, a double-blind, placebo-controlled, randomized trial was carried out...

  7. Tight Bounds for Lp Samplers, Finding Duplicates in Streams, and Related Problems

    CERN Document Server

    Jowhari, Hossein; Tardos, Gábor

    2010-01-01

    In this paper, we present near-optimal space bounds for Lp-samplers. Given a stream of updates (additions and subtraction) to the coordinates of an underlying vector x \\in R^n, a perfect Lp sampler outputs the i-th coordinate with probability |x_i|^p/||x||_p^p. In SODA 2010, Monemizadeh and Woodruff showed polylog space upper bounds for approximate Lp-samplers and demonstrated various applications of them. Very recently, Andoni, Krauthgamer and Onak improved the upper bounds and gave a O(\\epsilon^{-p} log^3 n) space \\epsilon relative error and constant failure rate Lp-sampler for p \\in [1,2]. In this work, we give another such algorithm requiring only O(\\epsilon^{-p} log^2 n) space for p \\in (1,2). For p \\in (0,1), our space bound is O(\\epsilon^{-1} log^2 n), while for the $p=1$ case we have an O(log(1/\\epsilon)\\epsilon^{-1} log^2 n) space algorithm. We also give a O(log^2 n) bits zero relative error L0-sampler, improving the O(log^3 n) bits algorithm due to Frahling, Indyk and Sohler. As an application of ou...

  8. COS FUV Detector Response to New HV Management System at LP3 {LENA4}

    Science.gov (United States)

    Penton, Steven

    2013-10-01

    This program uses a series of 205s WAVECALS and 60s DCE dumps to exercise the new HV Management System. We first ramp to the Maximum HV for Both Segment FUVA/FUVB = 178/175, we then transition to the minimum HV {A/B = 167/163} using the new HV management system, then transition back to the Maximum HV. The WAVECAL exposures at the Maximum HV will be taken with G160M/1611 {C1611} and the minimums are taken with G160M/1623 {C1623}. The CENWAVE change is required to allow time for the HV change. The sequence is repeated with FUVA ON {FUVB OFF}, and then with FUVB ON {FUVA OFF}. DCE Dumps are included before and after each WAVECAL.All exposures in the program should execute at the LP3 position, using the ALTERNATE lifetime position.This program will use a special HV Table with the following changes to the normal HV/Aperture table:CENWAVE Lifetime Position HVA/HVB--------------------------1611 Alternate {LP3} 178/1751623 Alternate {LP3} 167/163LP3 FUV aperture positions and SIAF file updates are not absolutely required, as these are all internals, but they are desired.

  9. Norra LP-mudel ajab Eestis juuri / intervjueerinud Sirje Pärismaa

    Index Scriptorium Estoniae

    2016-01-01

    Teaduspõhise LP-mudeli (Learning environment and pedagogical analysis) - abivahendi koolikultuuri parandamiseks ja süsteemsemaks lähenemiseks tekkinud probleemidele - on kasutusele võtnud 10 kooli ja 3 lasteaeda. Norra hariduseksperdid Janne Stoen ja Hanna Jahnsen vastasid Õpetajate Lehe küsimustele

  10. LP-REGULARITY FOR A CLASS OF PSEUDODIFFERENTIAL OPERATORS IN Rn

    Institute of Scientific and Technical Information of China (English)

    A Morando

    2005-01-01

    We study here a class of pseudodifferential operators with weighted symbols of Shubin type. First, we develop the basic elements of the pseudodifferential calculus for these operators, proving in particular a result of LP-boundedness. Then we derive regularity results in the frame of suitably defined functional spaces of Sobolev type.

  11. Mixed Norm Estimate for Radon Transform on Weighted $L^p$ Spaces

    Indian Academy of Sciences (India)

    Ashisha Kumar; Swagato K Ray

    2010-09-01

    We will discuss about the mapping property of Radon transform on $L^p$ spaces with power weight. It will be shown that the Pitt’s inequality together with the weighted version of Hardy–Littlewood–Sobolev lemma imply weighted inequality for the Radon transform.

  12. Increased plasma levels of Lp(a) enhance the development of coronary atherosclerosis

    Institute of Scientific and Technical Information of China (English)

    LI Ying; XU Hong; ZHOU Qin; WANG Chang-yuan; LIU Yan-xia; LU Yuan-yuan; FAN Jiang-lin; SUN Hui-jun

    2008-01-01

    Objective To test the hypothesis that increased plasma levels of Lp(a) may enhance the development of atherosclerosis in the setting of hypercholesterolemia. Methods The plasma Lp(a) was analyzed by SDS-PAGE Western blotting and quantitated using specific ELISA kits. Plasma total cholesterol, triglycerides and HDL-cholesterol were determined using Wako assay kits. The left coronary artery was used for the evaluation of coronary atherosclerosis (stenosis %). For quantitative study of the lesions in coronary atherosclerosis, hematoxylin- eosin and Elastica - van Gieson staining were used. To study cellular components ( SMC vs. macrophages) and Lp(a) deposits in the lesions, immunohistochemical staining was performed and then image analysis system was used. Results Plasma total cholesterol, triglycerides, or HDL-C were not significantly different between transgenic (Trg) and nontransgenic (nonTrg) rabbits. Trg rabbits had 200 % increase in coronary stenosis caused by atherosclerosis. The lesions of Trg WHHL rabbits contained more SMCs and less macrophage than those of nonTrg WHHL rabbits. Conclusions The results suggest that increased plasma levels of Lp(a) enhance the development of coronary atherosclerosis.

  13. 76 FR 38062 - Airworthiness Directives; Gulfstream Aerospace LP Model Galaxy and Gulfstream 200 Airplanes

    Science.gov (United States)

    2011-06-29

    ... LP Model Galaxy and Gulfstream 200 airplanes, certificated in any category, serial numbers 219 through 231 inclusive. Subject (d) Air Transport Association (ATA) of America Code 51: Standard Practices... A, dated January 25, 2010. (2) For airplanes having serial numbers 224 through 231 inclusive: Do the...

  14. Existence of global solution for a differential system with initial data in Lp

    Directory of Open Access Journals (Sweden)

    Peter Bates

    1999-01-01

    field within the earth. The system is similar to the magnetohydrodynamic (MHD equations. By establishing a new priori estimates and following Calderón's procedure for the Navier Stokes equations [1], we obtained, for initial data in space Lp, the global in time existence and uniqueness of weak solution of the system subject to appropriate conditions.

  15. The (Lp,(F)pβ,∞)-Boundedness of Commutators of Multipliers

    Institute of Scientific and Technical Information of China (English)

    Pu ZHANG; Jie Cheng CHEN

    2005-01-01

    In this paper, we study the commutator generalized by a multiplier and a Lipschitz function.Under some assumptions, we establish the boundedness properties of it from Lp(Rn) intoFβ,∞p(Rn):the Triebel-Lizorkin spaces.

  16. State of the Art in LP-WAN Solutions for Industrial IoT Services.

    Science.gov (United States)

    Sanchez-Iborra, Ramon; Cano, Maria-Dolores

    2016-05-17

    The emergence of low-cost connected devices is enabling a new wave of sensorization services. These services can be highly leveraged in industrial applications. However, the technologies employed so far for managing this kind of system do not fully cover the strict requirements of industrial networks, especially those regarding energy efficiency. In this article a novel paradigm, called Low-Power Wide Area Networking (LP-WAN), is explored. By means of a cellular-type architecture, LP-WAN-based solutions aim at fulfilling the reliability and efficiency challenges posed by long-term industrial networks. Thus, the most prominent LP-WAN solutions are reviewed, identifying and discussing the pros and cons of each of them. The focus is also on examining the current deployment state of these platforms in Spain. Although LP-WAN systems are at early stages of development, they represent a promising alternative for boosting future industrial IIoT (Industrial Internet of Things) networks and services.

  17. On Some Isomorphisms between Bounded Linear Maps and Non-Commutative Lp-Spaces

    Directory of Open Access Journals (Sweden)

    E. J. Atto

    2014-04-01

    Full Text Available We define a particular space of bounded linear maps using a Von Neumann algebra and some operator spaces. By this, we prove some isomorphisms, and using interpolation in some particular cases, we get analogue of non-commutative Lp spaces.

  18. L~p estimates for -equation on generalized complex ellipsoids

    Institute of Scientific and Technical Information of China (English)

    王伟

    2000-01-01

    The estimate of a holomorphic supporting function for the generalized complex ellipsoid in is given, This domain is not decoupled. By using this estimate, the best possible Lp estimates for the equation and some results of function theory on generalized complex ellipsoids are proved.

  19. State of the Art in LP-WAN Solutions for Industrial IoT Services

    Directory of Open Access Journals (Sweden)

    Ramon Sanchez-Iborra

    2016-05-01

    Full Text Available The emergence of low-cost connected devices is enabling a new wave of sensorization services. These services can be highly leveraged in industrial applications. However, the technologies employed so far for managing this kind of system do not fully cover the strict requirements of industrial networks, especially those regarding energy efficiency. In this article a novel paradigm, called Low-Power Wide Area Networking (LP-WAN, is explored. By means of a cellular-type architecture, LP-WAN–based solutions aim at fulfilling the reliability and efficiency challenges posed by long-term industrial networks. Thus, the most prominent LP-WAN solutions are reviewed, identifying and discussing the pros and cons of each of them. The focus is also on examining the current deployment state of these platforms in Spain. Although LP-WAN systems are at early stages of development, they represent a promising alternative for boosting future industrial IIoT (Industrial Internet of Things networks and services.

  20. Norra LP-mudel ajab Eestis juuri / intervjueerinud Sirje Pärismaa

    Index Scriptorium Estoniae

    2016-01-01

    Teaduspõhise LP-mudeli (Learning environment and pedagogical analysis) - abivahendi koolikultuuri parandamiseks ja süsteemsemaks lähenemiseks tekkinud probleemidele - on kasutusele võtnud 10 kooli ja 3 lasteaeda. Norra hariduseksperdid Janne Stoen ja Hanna Jahnsen vastasid Õpetajate Lehe küsimustele

  1. 77 FR 278 - Southcross Mississippi Pipeline, L.P. Notice of Extension of Time

    Science.gov (United States)

    2012-01-04

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Southcross Mississippi Pipeline, L.P. Notice of Extension of Time On...). Upon consideration, notice is hereby given that an extension of time for Southcross to file its...

  2. Lp APPROXIMATION BY GENERAL BERNSTEIN-DURRMEYER OPERATOR DEFINED ON SIMPLEX

    Institute of Scientific and Technical Information of China (English)

    Cao Feilong

    2004-01-01

    As a generalization of the Bernstein-Durrmeyer operators defined on the simplex, a class of general Bernstein- Durrmeyer operators is introduced. With the weighted moduli of smoothness as a metric, we prove a strong direct theorem and an inverse theorem of weak type for these operators by using a decomposition way. From the theorems the characterization of Lp approximation behavior is derived.

  3. 76 FR 65717 - Erie Boulevard Hydropower, L.P.; Notice of Availability of Environmental Assessment

    Science.gov (United States)

    2011-10-24

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Erie Boulevard Hydropower, L.P.; Notice of Availability of Environmental Assessment In accordance with the National Environmental Policy Act of 1969 and the Federal Energy Regulatory...

  4. 76 FR 46287 - Erie Boulevard Hydropower, L.P.; Notice of Availability of Environmental Assessment

    Science.gov (United States)

    2011-08-02

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Erie Boulevard Hydropower, L.P.; Notice of Availability of Environmental Assessment In accordance with the National Environmental Policy Act of 1969 and the Federal Energy Regulatory...

  5. Survival associated pathway identification with group Lp penalized global AUC maximization

    Directory of Open Access Journals (Sweden)

    Liu Zhenqiu

    2010-08-01

    Full Text Available Abstract It has been demonstrated that genes in a cell do not act independently. They interact with one another to complete certain biological processes or to implement certain molecular functions. How to incorporate biological pathways or functional groups into the model and identify survival associated gene pathways is still a challenging problem. In this paper, we propose a novel iterative gradient based method for survival analysis with group Lp penalized global AUC summary maximization. Unlike LASSO, Lp (p 1. We first extend Lp for individual gene identification to group Lp penalty for pathway selection, and then develop a novel iterative gradient algorithm for penalized global AUC summary maximization (IGGAUCS. This method incorporates the genetic pathways into global AUC summary maximization and identifies survival associated pathways instead of individual genes. The tuning parameters are determined using 10-fold cross validation with training data only. The prediction performance is evaluated using test data. We apply the proposed method to survival outcome analysis with gene expression profile and identify multiple pathways simultaneously. Experimental results with simulation and gene expression data demonstrate that the proposed procedures can be used for identifying important biological pathways that are related to survival phenotype and for building a parsimonious model for predicting the survival times.

  6. Provably Efficient Instanton Search Algorithm for LP decoding of LDPC codes over the BSC

    CERN Document Server

    Chilappagari, Shashi Kiran

    2008-01-01

    We consider Linear Programming (LP) decoding of a Low-Density Parity-Check (LDPC) code performing over the Binary Symmetric Channel (BSC). The LP decoder fails when it outputs a pseudo-codeword which is not a codeword. Following the approach of [1], we design an efficient algorithm termed the Instanton Search Algorithm (ISA) which, given a random input, generates a set of flips, called BSC-instanton, such that the LP decoder decodes the instanton into a pseudo-codeword distinct from the all-zero-codeword while any reduction of the instanton leads to the all-zero-codeword. We prove that (a) the LP decoder fails for any set of flips with support vector including an instanton; (b) for any original input, the algorithm outputs an instanton in the number of steps upper-bounded by twice the number of actual flips in the input. Repeated sufficient number of times, the ISA outcomes the number of unique instantons of different sizes. We illustrate the performance of the algorithm on the [155,64,20] Tanner code and sho...

  7. Draft Genome Sequences of Legionella pneumophila JR32 and Lp01 Laboratory Strains Domesticated in Japan

    Science.gov (United States)

    Maita, Chinatsu; Matushita, Mizue; Okubo, Torahiko; Matsuo, Junji; Miyake, Masaki; Nagai, Hiroki

    2016-01-01

    We report here the draft genome sequences of two Legionella pneumophila variant strains (JR32 and Lp01_666) originally derived from a Philadelphia-1 clinical isolate, domesticated in Japan, with distinct susceptibility to amoebae. Detailed genomic analysis will allow us to better understand Legionella adaptation and survival mechanisms in host cells. PMID:27491976

  8. 77 FR 44113 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

    Science.gov (United States)

    2012-07-27

    ... Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Airplanes AGENCY... previously held by Israel Aircraft Industries, Ltd.) Model Gulfstream G150 airplanes. This emergency AD was... previously held by Israel Aircraft Industries, Ltd.) Model Gulfstream G150 airplanes. These conditions...

  9. 77 FR 58323 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

    Science.gov (United States)

    2012-09-20

    ... Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Airplanes AGENCY... Previously Held by Israel Aircraft Industries, Ltd.) Model Gulfstream G150 airplanes. This proposed AD was... Previously Held by Israel Aircraft ] Industries, Ltd.): Docket No. FAA-2012-0986; Directorate Identifier...

  10. 75 FR 57844 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

    Science.gov (United States)

    2010-09-23

    ... Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Model Galaxy and... Held by Israel Aircraft Industries, Ltd.): Amendment 39-16438. Docket No. FAA-2010-0555; Directorate... Certificate previously held by Israel Aircraft Industries, Ltd.) Model Galaxy and Gulfstream 200...

  11. 77 FR 74658 - Texas Eastern Transmission, LP; Notice of Technical Conference

    Science.gov (United States)

    2012-12-17

    ... conference be held to address issues raised by Texas Eastern Transmission, LP's proposed revisions to its...,172 (2012). Take notice that a technical conference will be held on Tuesday, January 15, 2013 at 9:30... please contact David Maranville at (202) 502-6351 or email David.Maranville@ferc.gov . Dated: December...

  12. 75 FR 27774 - Eagle Rock Desoto Pipeline, L.P.; Notice of Rate Election

    Science.gov (United States)

    2010-05-18

    ... [Federal Register Volume 75, Number 95 (Tuesday, May 18, 2010)] [Notices] [Page 27774] [FR Doc No: 2010-11793] DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-22-000] Eagle..., Eagle Rock Desoto Pipeline, L.P., (Desoto) filed a Notice of Rate Election pursuant to section...

  13. 75 FR 65467 - Enterprise Alabama Intrastate, LLC; Enterprise Intrastate L.P; Notice of Baseline Filings

    Science.gov (United States)

    2010-10-25

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Enterprise Alabama Intrastate, LLC; Enterprise Intrastate L.P; Notice of Baseline Filings October 18, 2010. Take notice that on October 15, 2010, the applicants listed above...

  14. 76 FR 70438 - Enterprise Intrastate L.P., Enterprise Texas Pipeline LLC; Notice of Filing

    Science.gov (United States)

    2011-11-14

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Enterprise Intrastate L.P., Enterprise Texas Pipeline LLC; Notice of Filing Take notice that on November 1, 2011, the applicants listed above filed a revised Statement of...

  15. TRIGONOMETRIC QUASI-GREEDY BASES FOR L-p (T; w)

    DEFF Research Database (Denmark)

    Nielsen, Morten

    2009-01-01

    We give a complete characterization of 2π-periodic weights w for which the usual trigonometric system forms a quasi-greedy basis for Lp(T;w), i.e. bases for which simple thresholding approximants converge in norm. The characterization implies that this can happen only for p=2 and whenever...

  16. 78 FR 6828 - Accreditation and Approval of Saybolt LP, as a Commercial Gauger and Laboratory

    Science.gov (United States)

    2013-01-31

    ... SECURITY U.S. Customs and Border Protection Accreditation and Approval of Saybolt LP, as a Commercial Gauger and Laboratory AGENCY: U.S. Customs and Border Protection, Department of Homeland Security. ACTION...: Approved Gauger and Accredited Laboratories Manager, Laboratories and Scientific Services, U.S. Customs...

  17. 77 FR 34055 - Accreditation and Approval of Saybolt LP, as a Commercial Gauger and Laboratory

    Science.gov (United States)

    2012-06-08

    ... SECURITY U.S. Customs and Border Protection Accreditation and Approval of Saybolt LP, as a Commercial Gauger and Laboratory AGENCY: U.S. Customs and Border Protection, Department of Homeland Security. ACTION...: Christopher Mocella, Laboratories and Scientific Services, U.S. Customs and Border Protection,...

  18. 78 FR 7442 - Accreditation and Approval of Chemical and Petrochemical Inspections, LP, as a Commercial Gauger...

    Science.gov (United States)

    2013-02-01

    ... SECURITY U.S. Customs and Border Protection Accreditation and Approval of Chemical and Petrochemical Inspections, LP, as a Commercial Gauger and Laboratory AGENCY: U.S. Customs and Border Protection, Department... and Accredited Laboratories Manager, Laboratories and Scientific Services, U.S. Customs and...

  19. 76 FR 9807 - Accreditation and Approval of Saybolt LP, as a Commercial Gauger and Laboratory

    Science.gov (United States)

    2011-02-22

    ... SECURITY U.S. Customs and Border Protection Accreditation and Approval of Saybolt LP, as a Commercial Gauger and Laboratory AGENCY: U.S. Customs and Border Protection, Department of Homeland Security. ACTION... Scientific Services, U.S. Customs and Border Protection, 1300 Pennsylvania Avenue, NW., Suite...

  20. A new LP formulation of the admission control problem modelled as an MDP under average reward criterion

    Science.gov (United States)

    Pietrabissa, Antonio

    2011-12-01

    The admission control problem can be modelled as a Markov decision process (MDP) under the average cost criterion and formulated as a linear programming (LP) problem. The LP formulation is attractive in the present and future communication networks, which support an increasing number of classes of service, since it can be used to explicitly control class-level requirements, such as class blocking probabilities. On the other hand, the LP formulation suffers from scalability problems as the number C of classes increases. This article proposes a new LP formulation, which, even if it does not introduce any approximation, is much more scalable: the problem size reduction with respect to the standard LP formulation is O((C + 1)2/2 C ). Theoretical and numerical simulation results prove the effectiveness of the proposed approach.

  1. LP-Based Approximation Algorithms for Traveling Salesman Path Problems

    CERN Document Server

    An, Hyung-Chan

    2011-01-01

    We present a (5/3 - epsilon)-approximation algorithm for some constant epsilon>0 for the traveling salesman path problem under the unit-weight graphical metric, and prove an upper bound on the integrality gap of the path-variant Held-Karp relaxation both under this metric and the general metric. Given a complete graph with the metric cost and two designated endpoints in the graph, the traveling salesman path problem is to find a minimum Hamiltonian path between these two endpoints. The best previously known performance guarantee for this problem was 5/3 and was due to Hoogeveen. We give the first constant upper bound on the integrality gap of the path-variant Held-Karp relaxation, showing it to be at most 5/3 by providing a new analysis of Hoogeveen's algorithm. This analysis exhibits a well-characterized critical case, and we show that the recent result of Oveis Gharan, Saberi and Singh on the traveling salesman circuit problem under the unit-weight graphical metric can be modified for the path case to compl...

  2. k-Edge-Connectivity: Approximation and LP Relaxation

    CERN Document Server

    Pritchard, David

    2010-01-01

    This paper's focus is the following family of problems, denoted k-ECSS, where k denotes a positive integer: given a graph (V, E) and costs for each edge, find a minimum-cost subset F of E such that (V, F) is k-edge-connected. For k=1 it is the spanning tree problem which is in P; for every other k it is APX-hard and has a 2-approximation. Moreover, assuming P != NP, it is known that for unit costs, the best possible approximation ratio is 1 + Theta(1/k) for k>1. Our first main result is to determine the analogous asymptotic ratio for general costs: we show there is a constant eps>0 so that for all k>1, finding a (1+eps)-approximation for k-ECSS is NP-hard. Thus we establish a gap between the unit-cost and general-cost versions, for large enough k. Next, we consider the multi-subgraph cousin of k-ECSS, in which we are allowed to buy arbitrarily many copies of any edges (i.e., F is now a multi-subset of E, with parallel copies having the same cost as the original edge). Not so much is known about this natural v...

  3. Two-Look Polarimetric (2LP) Microwave Radiometers for Ocean Vector Wind Retrieval

    Science.gov (United States)

    Wentz, F. J.; Hilburn, K. A.; Meissner, T.; Brown, S. E.

    2014-12-01

    This talk discusses the future utilization of two-look polarimetric (2LP) microwave radiometers for measuring the ocean surface wind vector. Potentially, these 2LP satellite radiometers offer two advantages over conventional scatterometers: unambiguous wind vector retrievals and low-cost. One concept for a 2LP radiometer is being developed by JPL and is called the Compact Ocean Wind Vector Radiometer (COWVR). A space demonstration of COWVR is planned for 2016 timeframe. To explore the potential of 2LP radiometers, we use the 11 years of WindSat observations as a testbed. We only use that portion of the WindSat swath that has both fore and aft observations. WindSat provides fully polarimetric observations (all four Stokes parameters) at 11, 19, and 37 GHz. This represents 12 independent channels for each of the two azimuth directions. A wind vector retrieval algorithm is developed to fully utilize this wide assortment of information. Since this analysis is based on actual observations, it provides a realistic picture of what to expect from future 2LP radiometers. To our knowledge, this is the first time that the combination of WindSat's fore and aft observations has been fully utilized for wind vector retrievals. In our talk we compare the 2LP wind vector retrieval performance with that of single-look polarimetric radiometers (i.e., WindSat standard product) and scatterometers. We provide basic statistics from a triple collocation between winds from WindSat, QuikScat, and NDBC/PMEL ocean moored buoys. The statistics include the standard deviation of the first ranked ambiguity direction, skill rate, and number of ambiguities. All available data from the common period of operation between WindSat and QuikScat (2003-2009) are used. We characterize the wind direction accuracy as a function of wind speed, and show how 2LP retrievals are able to extend the wind vector accuracy to lower wind speeds than previously considered possible for radiometers.

  4. Intensive lifestyle modification reduces Lp-PLA2 in dyslipidemic HIV/HAART patients.

    Science.gov (United States)

    Wooten, Joshua S; Nambi, Preethi; Gillard, Baiba K; Pownall, Henry J; Coraza, Ivonne; Scott, Lynne W; Nambi, Vijay; Ballantyne, Christie M; Balasubramanyam, Ashok

    2013-06-01

    Patients with dyslipidemia associated with HIV-1 infection and highly active antiretroviral therapy (HAART) have elevated levels of Lp-PLA2 and CCL5/regulated on activation, normal T-cell expressed and secreted (RANTES), which may increase the risk of cardiovascular disease. This study aimed to determine whether an intensive diet and exercise (D/E) program, independently or combined with fenofibrate or niacin, could reduce Lp-PLA2 or RANTES. Patients with hypertriglyceridemic HIV on stable HAART (n = 107) were randomized to one of five interventions: 1) usual care, 2) D/E with placebos, 3) D/E with fenofibrate and placebo, 4) D/E with niacin and placebo, or 5) D/E with fenofibrate and niacin for 24 wk. Lp-PLA2 and RANTES concentrations were measured in fasting plasma samples at baseline and postintervention. General linear models were used to compare Lp-PLA2 and RANTES levels between the five groups postintervention, controlling for baseline levels, age, body mass index, CD4 T-cell count, viral load, duration of infection, and HAART. At baseline, fasting plasma Lp-PLA2 (388.5 ± 127.5 ng·mL) and RANTES (43.8 ± 25.5 ng·mL) levels were elevated when compared with healthy controls. Posttreatment Lp-PLA2 mass was lower in patients who received D/E only (323.0 ± 27.2 ng·mL), D/E plus fenofibrate (327.2 ± 25.9 ng·mL), and D/E plus niacin (311.1 ± 27.8 ng·mL) when compared with patients receiving usual care (402.2 ± 25.3 ng·mL). RANTES concentrations were not significantly affected by any intervention. Elevated plasma Lp-PLA2 mass can be reduced by an intensive D/E program in patients with HIV/HAART-associated dyslipidemia. RANTES is elevated but is not reduced by lifestyle modification, fenofibrate, or niacin.

  5. Association of Lp-PLA2 Mass and Aysmptomatic Intracranial and Extracranial Arterial Stenosis in Hypertension Patients

    Science.gov (United States)

    Wang, Yan; Zhang, Jin; Qian, Yuesheng; Tang, Xiaofeng; Ling, Huawei; Chen, Kemin; Gao, Pingjin; Zhu, Dingliang

    2015-01-01

    Background and Purpose Intracranial arterial stenosis (ICAS) is a common cause of ischemic stroke in Asians, whereas whites tend to have more extracranial lesions. Lipoprotein-associated phospholipase A2 (Lp-PLA2) has been associated with ischemic stroke by a large amount of work. However, there are few studies focusing on the relationship of Lp-PLA2 and asymptomatic ICAS or extracranial arterial stenosis (ECAS). Wehereby sought to explore the relationship of Lp-PLA2 and ICAS, ECAS and concurrent stenosis in stroke-free hypertensive patients in Chinese population. Methods All the subjects were evaluated for the presence and severity of ICAS and ECAS through computerized tomographic angiography (CTA) covered the whole brain down to the level of aortic arch. Lp-PLA2 mass was measured by enzyme linked immunoassay. The association of Lp-PLA2 and vascular stenosis was analyzed through multivariate logistic regression. Results Among 414 participants, 163 (39.4%) had no ICAS or ECAS, 63 (15.2%) had ECAS only, 111 (26.8%) had ICAS only and 77 (18.6%) had concurrent extraintracranial stenosis. Lp-PLA2 mass was significantly associated with isolated ICAS (OR: 2.3; 95% CI: 1.14-4.64), and concurrent stenosis (OR: 3.93; 95% CI: 1.62-9.51), but was not related to isolated ECAS (OR: 1.54; 95% CI: 0.68-3.48). Lp-PLA2 mass was also associated with moderate to severe ICAS no matter how was the ECAS. Moreover, patients with higher Lp-PLA2 mass showed more sever ICAS and had more intracranial arterial lesions. Conclusion This study revealed the association of Lp-PLA2 mass with ICAS in stroke-free hypertensive patients in Chinese population. The further long-term cohort study was warranted to elucidate the concrete effect of Lp-PLA2 on the asymptomatic ICAS. PMID:26098634

  6. Learning to perceive and recognize a second language: the L2LP model revised

    Science.gov (United States)

    van Leussen, Jan-Willem; Escudero, Paola

    2015-01-01

    We present a test of a revised version of the Second Language Linguistic Perception (L2LP) model, a computational model of the acquisition of second language (L2) speech perception and recognition. The model draws on phonetic, phonological, and psycholinguistic constructs to explain a number of L2 learning scenarios. However, a recent computational implementation failed to validate a theoretical proposal for a learning scenario where the L2 has less phonemic categories than the native language (L1) along a given acoustic continuum. According to the L2LP, learners faced with this learning scenario must not only shift their old L1 phoneme boundaries but also reduce the number of categories employed in perception. Our proposed revision to L2LP successfully accounts for this updating in the number of perceptual categories as a process driven by the meaning of lexical items, rather than by the learners' awareness of the number and type of phonemes that are relevant in their new language, as the previous version of L2LP assumed. Results of our simulations show that meaning-driven learning correctly predicts the developmental path of L2 phoneme perception seen in empirical studies. Additionally, and to contribute to a long-standing debate in psycholinguistics, we test two versions of the model, with the stages of phonemic perception and lexical recognition being either sequential or interactive. Both versions succeed in learning to recognize minimal pairs in the new L2, but make diverging predictions on learners' resulting phonological representations. In sum, the proposed revision to the L2LP model contributes to our understanding of L2 acquisition, with implications for speech processing in general. PMID:26300792

  7. Learning to perceive and recognize a second language: the L2LP model revised

    Directory of Open Access Journals (Sweden)

    Jan-Willem eVan Leussen

    2015-08-01

    Full Text Available We present a test of a revised version of the Second Language Linguistic Perception (L2LP model, a computational model of the acquisition of second language (L2 speech perception and recognition. The model draws on phonetic, phonological and psycholinguistic constructs to explain a number of L2 learning scenarios. However, a recent computational implementation failed to validate a theoretical proposal for a learning scenario where the L2 has less phonemic categories than the native language (L1 along a given acoustic continuum. According to the L2LP, learners faced with this learning scenario must not only shift their old L1 phoneme boundaries but also reduce the number of categories employed in perception. Our proposed revision to L2LP successfully accounts for this updating in the number of perceptual categories as a process driven by the meaning of lexical items, rather than by the learners’ awareness of the number and type of phonemes that are relevant in their new language, as the previous version of L2LP assumed. Results of our simulations show that meaning-driven learning correctly predicts the developmental path of L2 phoneme perception seen in empirical studies. Additionally, and to contribute to a long-standing debate in psycholinguistics, we test two versions of the model, with the stages of phonemic perception and lexical recognition being either sequential or interactive. Both versions succeed in learning to recognize minimal pairs in the new L2, but make diverging predictions on learners' resulting phonological representations. In sum, the proposed revision to the L2LP model contributes to our understanding of L2 acquisition, with implications for speech processing in general.

  8. Learning to perceive and recognize a second language: the L2LP model revised.

    Science.gov (United States)

    van Leussen, Jan-Willem; Escudero, Paola

    2015-01-01

    We present a test of a revised version of the Second Language Linguistic Perception (L2LP) model, a computational model of the acquisition of second language (L2) speech perception and recognition. The model draws on phonetic, phonological, and psycholinguistic constructs to explain a number of L2 learning scenarios. However, a recent computational implementation failed to validate a theoretical proposal for a learning scenario where the L2 has less phonemic categories than the native language (L1) along a given acoustic continuum. According to the L2LP, learners faced with this learning scenario must not only shift their old L1 phoneme boundaries but also reduce the number of categories employed in perception. Our proposed revision to L2LP successfully accounts for this updating in the number of perceptual categories as a process driven by the meaning of lexical items, rather than by the learners' awareness of the number and type of phonemes that are relevant in their new language, as the previous version of L2LP assumed. Results of our simulations show that meaning-driven learning correctly predicts the developmental path of L2 phoneme perception seen in empirical studies. Additionally, and to contribute to a long-standing debate in psycholinguistics, we test two versions of the model, with the stages of phonemic perception and lexical recognition being either sequential or interactive. Both versions succeed in learning to recognize minimal pairs in the new L2, but make diverging predictions on learners' resulting phonological representations. In sum, the proposed revision to the L2LP model contributes to our understanding of L2 acquisition, with implications for speech processing in general.

  9. Defense styles of pedophilic offenders.

    Science.gov (United States)

    Drapeau, Martin; Beretta, Véronique; de Roten, Yves; Koerner, Annett; Despland, Jean-Nicolas

    2008-04-01

    This pilot study investigated the defense styles of pedophile sexual offenders. Interviews with 20 pedophiles and 20 controls were scored using the Defense Mechanisms Rating Scales. Results showed that pedophiles had a significantly lower overall defensive functioning score than the controls. Pedophiles used significantly fewer obsessional-level defenses but more major image-distorting and action-level defenses. Results also suggested differences in the prevalence of individual defenses where pedophiles used more dissociation, displacement, denial, autistic fantasy, splitting of object, projective identification, acting out, and passive aggressive behavior but less intellectualization and rationalization.

  10. Anti-tumor activity of heat-killed Lactobacillus plantarum BF-LP284 on Meth-A tumor cells in BALB/c mice.

    Science.gov (United States)

    Shin, Ryoichi; Itoh, Yukie; Kataoka, Motoyuki; Iino-Miura, Shiori; Miura, Ryosuke; Mizutani, Takeo; Fujisawa, Tomohiko

    2016-09-01

    Probiotics exert numerous effects on human well-being. Here, heat-killed Lactobacillus plantarum BF-LP284 (H-Lp) was isolated as a potent immuno-modulator among 15 strains of lactobacilli in terms of TNF-α induction ability in peritoneal macrophages. In vitro TNF-α and IFN-γ induction in Peyer's patch (PP) cells was higher when incubated with H-Lp than with live L. plantarum BF-LP284 (L-Lp). Suppression of syngeneic Meth-A tumors in a murine model by oral administration of H-Lp was also greater than that of L-Lp and of controls. H-Lp stimulated IFN-γ production in spleen cells, which displayed inhibited tumor growth in Winn assays when treated with H-Lp. Moreover, H-Lp increased the ratio of CD3(+ )cells among peripheral blood mononuclear cells in Meth-A tumor-bearing mice, suggesting an H-Lp-mediated anti-tumor mechanism whereby immune cells that are activated by H-Lp in PP and acquire anti-tumor activity in the spleen migrate to tumor sites through lymphocyte homing to inhibit tumor growth.

  11. 76 FR 78958 - Bureau of Political Military Affairs: Directorate of Defense Trade Controls; Notifications to the...

    Science.gov (United States)

    2011-12-20

    ... Ministry of Defense of Malaysia. The United States Government is prepared to license the export of these... manufacture of the M72A5 Light Anti-Armor Weapon (LAW) system for the Canadian Department of National Defense... domestic law enforcement and government agency customers in the approved sales territory. The United...

  12. Characterization of human gene encoding SLA/LP autoantigen and its conserved homologs in mouse,fish,fly,and worm

    Institute of Scientific and Technical Information of China (English)

    Chun-Xia Wang; Andreas Teufel; Uta Cheruti; Joachim Gr(o)tzinger; Peter R Galle; Ansgar W Lohse; Johannes Herkel

    2006-01-01

    AIM: To approach the elusive function of the SLA/LP molecule, we have characterized genomic organization and conservation of the major antigenic and functional properties of the SLA/LP molecule in various species.METHODS: By means of computational biology, we have characterized the complete SLA/LP gene, mRNA and deduced protein sequences in man, mouse,zebrafish, fly, and worm.RESULTS: The human SLA/LP gene sequence of approximately 39 kb, which maps to chromosome 4p15.2, is organized in 11 exons, of which 10 or 11 are translated, depending on the splice variant. Homologous molecules were identified in several biological model organisms. The various homologous protein sequences showed a high degree of similarity or homology, notably at those residues that are of functional importance. The only domain of the human protein sequence that lacks significant homology with homologous sequences is the major antigenic epitope recognized by autoantibodies from autoimmune hepatitis (AIH) patients.CONCLUSION: The SLA/LP molecule and its functionally relevant residues have been highly conserved throughout the evoluti n, suggesting an indispensable function of the molecule. The finding that the only non-conserved domain is the dominant antigenic epitope of the human SLA/LP sequence, suggests that SLA/LP autoimmunity is autoantigen-driven rather than being driven by molecular mimicry.

  13. Russian Ballistic Missile Defense: Rhetoric and Reality

    Science.gov (United States)

    2015-06-01

    2012/06/08/russia_installs_new_radars_as_a_ deterrent_15834.html. 130. “Direct Line with Vladimir Putin ,” President of Russia , April 17, 2014...and increases the danger of war. In his 2012 pre-election treatise on defense policy and national security, Rus- sian President Vladimir Putin ...Kontsern PVO Almaz-Antey) was established by President Vladimir Putin in 2002 uniting no fewer than 46 enterprises, including factories, research and

  14. Affordability Constraints in Major Defense Acquisitions

    Science.gov (United States)

    2016-11-01

    price , this is actually an inverse supply curve. In competitive markets, the inverse supply curve is the firm’s marginal cost curve. When firms have a...support features and functions. The vertical axis represents the unit sale price , inclusive of all life-cycle or total ownership costs as appropriate...Three Defense Programs 3 We can easily extend the example to incorporate cost - plus payment schemes

  15. Defense Primer: A Guide for New Members

    Science.gov (United States)

    2017-03-03

    3 Research, Development , Test, and Evaluation .......................................................................... 3 Defense...Navy,” “to make Rules for the Government and Regulation of the land and naval Forces,” and “to provide for organizing , arming, and disciplining the...Militia, and for governing such Part of them as may be employed in the Service of the United States.... ” CRS has developed a series of short

  16. Defense Research Enterprise Assessment

    Science.gov (United States)

    2017-01-01

    Please review the report findings and recommendations. I am interested in receiving your feedback for inclusion in programs wherever these...needed culture shift to utilize their existing authorities. Finally, expanded coordination among intermural basic research portfolios across the Labs...research portfolios across the Labs without creating additional administrative burdens is needed. The defense research enterprise should

  17. AFRL Defensive IO Programs

    Science.gov (United States)

    2007-11-02

    Wireless Information Assurance • Steganography • Air Force Enterprise Defense (AFED) 10 Distributed Agents for Information Warfare Operational...information (images, documents, overlays, audio , links, etc.) •multi-level data release to coalition forces; key-based access •covert communication...maximize throughput of communication channels Data Hiding/Embedding Steganography Watermarking Steganalysis 14 Payoffs • Integrates existing

  18. Defense Business Transformation

    Science.gov (United States)

    2009-12-01

    other. SCM and ERP systems both contribute to the overall distribution and coordination of resources. Just as an ERP enhances information flow...inventory management system (Thureen 2008). It combines the Army’s disparate wholesale and retail inventories, into one combined system (Sparacino 2002...Studies.............................................................................. 73 1. Defense Integrated Military Human Resource System

  19. Robust Preallocated Preferential Defense.

    Science.gov (United States)

    1985-08-01

    Frye , W.H. and Ullman, L.L., Methodology for Calculating Minuteman Defense Effectiveness, SRD-EGI4, Stanford Research Institute, October 1973. 4. Hogg...Corporation 1500 Wilson Boulevard Arlington, VA 22209 ATTN: Dr. Tucker Battle Dr. James Skouras Dr. Iram Weinstein Northrop Corporation 8900 E. Washington

  20. Needed: Reincarnation of National Defense Education Act of 1958

    Science.gov (United States)

    Harris, Mary M.; Miller, James R.

    2005-01-01

    This paper reviews the historical and current response of the United States to threats to its world leadership in scientific endeavors, with particular attention to the National Defense Education Act of 1958. The current status of the United States in mathematics, science, and engineering education is reviewed with respect to K-12 student…

  1. Defense Institution Building: An Assessment

    Science.gov (United States)

    2016-01-01

    MoDA and DIILS Support of DIB Activity Objectives . . . . . . . 26 2.8. Overlapping Program Objectives...Wales Initiative Fund–Defense Institution Building (WIF-DIB), the Ministry of Defense Advisors ( MoDA ) program, and the Defense Insti- tute of...other events and activities related to a partner nation’s defense institution capabilities and capacity. One exception is MoDA , where engagements are

  2. Lp-decay rates to nonlinear diffusion waves for p-system with nonlinear damping

    Institute of Scientific and Technical Information of China (English)

    ZHU Changjiang; JIANG Mina

    2006-01-01

    In this paper, we study the Lp (2 ≤ p ≤ +∞) convergence rates of the solutions to the Cauchy problem of the so-called p-system with nonlinear damping. Precisely, we show that the corresponding Cauchy problem admits a unique global solution (v(x,t),u(x,t)) and such a solution tends time-asymptotically to the corresponding nonlinear diffusion wave (-v(x, t), -u(x, t)) governed by the classical Darcy's law provided that the corresponding prescribed initial error function (w0(x), z0(x))lies in (H3 × H2) (R) and |v+ - v-| + ‖w0‖3 + ‖z0‖2 is sufficiently small.Furthermore, the Lp (2 ≤ p ≤ +∞) convergence rates of the solutions are also obtained.

  3. 兰博基尼发布LP650-4

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    兰博基尼近日发布了Murcielago LP650-4敞篷车,由于该车仅限量生产50辆,因此预计其售价将是个天文数.LP650-4敞篷车搭载一台6.5升V12发动机,最大可以达到惊人的650马力。该车还采用了四驱系统,百公里加速时间仅为3.4秒,最高时速330公里。

  4. Human SepSecS or SLA/LP: selenocysteine formation and autoimmune hepatitis.

    Science.gov (United States)

    Palioura, Sotiria; Herkel, Johannes; Simonović, Miljan; Lohse, Ansgar W; Söll, Dieter

    2010-07-01

    Selenocysteine, the 21st genetically encoded amino acid, is the major form of the antioxidant trace element selenium in the human body. In eukaryotes and archaea its synthesis proceeds through a phosphorylated intermediate in a tRNA-dependent fashion. The final step of selenocysteine formation is catalyzed by O-phosphoseryl-tRNA:selenocysteinyl-tRNA synthase (SepSecS) that converts phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec). The human SepSecS protein is also known as soluble liver antigen/liver pancreas (SLA/LP), which represents one of the antigens of autoimmune hepatitis. Here we review the discovery of human SepSecS and the current understanding of the immunogenicity of SLA/LP in autoimmune hepatitis.

  5. PCSK9 inhibition-mediated reduction in Lp(a) with evolocumab: an analysis of 10 clinical trials and the LDL receptor's role.

    Science.gov (United States)

    Raal, Frederick J; Giugliano, Robert P; Sabatine, Marc S; Koren, Michael J; Blom, Dirk; Seidah, Nabil G; Honarpour, Narimon; Lira, Armando; Xue, Allen; Chiruvolu, Padmaja; Jackson, Simon; Di, Mei; Peach, Matthew; Somaratne, Ransi; Wasserman, Scott M; Scott, Rob; Stein, Evan A

    2016-06-01

    Lipoprotein (a) [Lp(a)] is independently associated with CVD risk. Evolocumab, a monoclonal antibody (mAb) to proprotein convertase subtilisin/kexin type 9 (PCSK9), decreases Lp(a). The potential mechanisms were assessed. A pooled analysis of Lp(a) and LDL cholesterol (LDL-C) in 3,278 patients from 10 clinical trials (eight phase 2/3; two extensions) was conducted. Within each parent study, biweekly and monthly doses of evolocumab statistically significantly reduced Lp(a) at week 12 versus control (P evolocumab, particularly in the setting of low circulating LDL, Lp(a) is reduced.

  6. Lp and L∞ Norm Estimates of the Cost of the Controllability for Heat Equations

    Institute of Scientific and Technical Information of China (English)

    Pei Dong LEI; Xu LIU; Hang GAO

    2009-01-01

    This paper is concerned with the bound of the cost of approximate controllability and null controllability of heat equations, i.e., the minimal Lp norm and L∞ norm of a control needed to control the system approximately or a control needed to steer the state of the system to zero. The methods we use combine observability inequalities, energy estimates for heat equations and the dual theory.

  7. Construction of Markov process with Markov resolvent on Lp(E,m)

    Institute of Scientific and Technical Information of China (English)

    董昭

    1997-01-01

    Lei E be a Hausdorff topological space and let A(E) be its Borel σ-field.Let m be a σ-finitc measure on (E,A(E)).A necessary and sufficient condition for a Markov resolvent on Lp(E,m ) to be associated with an m-tight m-special standard process (with state space E) is given.Furthermore some new examples which do not belong to the framework of Dirichlet space are also given.

  8. Polyketides from the plant endophytic fungus Cladosporium sp. IFB3lp-2.

    Science.gov (United States)

    Wuringege; Guo, Zhi-Kai; Wei, Wei; Jiao, Rui-Hua; Yan, Tong; Zang, Le-Yun; Jiang, Rong; Tan, Ren-Xiang; Ge, Hui-Ming

    2013-09-01

    Chemical study of the ethyl acetate extract of the plant endophytic fungus Cladosporium sp. (strain no. IFB3lp-2) yielded three new polyketides (1-3), together with nine known compounds. All of the structures were elucidated on the basis of spectroscopic methods. The isolated compounds were screened for their cytotoxic, antiviral, and acetyl cholinesterase inhibitory activities. Regretfully, no compounds showed any significant activity in these assays.

  9. A convolution type characterization for Lp - multipliers for the Heisenberg group

    Directory of Open Access Journals (Sweden)

    R. Radha

    2007-01-01

    Full Text Available It is well known that if m is an Lp - multiplier for the Fourier transform on ℝn(1

  10. Estimates of Lp Modulus of Continuity of Generalized Bounded Variation Classes

    Directory of Open Access Journals (Sweden)

    Heping Wang

    2014-01-01

    Full Text Available Some sharp estimates of the Lp1≤p<∞ modulus of continuity of classes of Λφ-bounded variation are obtained. As direct applications, we obtain estimates of order of Fourier coefficients of functions of Λφ-bounded variation, and we also characterize some sufficient and necessary conditions for the embedding relations Hpω⊂ΛφBV. Our results include the corresponding known results of the class ΛBV as a special case.

  11. 极速代言人——Lamborghini Murcielago LP 648

    Institute of Scientific and Technical Information of China (English)

    刘畅

    2006-01-01

    兰博基尼公司在超级跑车Murcielago的基础上再度投入热情,于是诞生了更强大的LP640。这款车的命名来自其发动机的重要指标,L表示纵向(longitudinale),P表示后置(posteriore),然后是640hp的最大功率。

  12. 速度之魔 兰博基尼Aventador LP700—4

    Institute of Scientific and Technical Information of China (English)

    高华; Lamborghini(摄影)

    2011-01-01

    上一代蛮牛Murcielago经历了10年的市场考验,终于退役,新蛮牛Aventador LP700—4接班上台。这个名字来自西班牙一头勇猛的公牛,而它的骁勇只需看看名字后面的最大功率——700马力(515kW).

  13. 牛之轻则狂--兰博基尼Aventador LP 700—4

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    提到轻量化跑车,怎能落下兰博基尼Aventador LP700—4这头大牛。作为murcielago的全新换代车型。Aventador在车身以及发动机上尽可能采用轻量化材料从而降低整车重量。

  14. Genetic invalidation of Lp-PLA2 as a therapeutic target

    DEFF Research Database (Denmark)

    Gregson, John M; Freitag, Daniel F; Surendran, Praveen

    2017-01-01

    .95 (0.88-1.03) with Val279Phe; 0.92 (0.74-1.16) with carriage of any loss-of-function variant; 1.01 (0.68-1.51) with Val379Ala; and 0.95 (0.89-1.02) with darapladib treatment. CONCLUSIONS: In a large-scale human genetic study, none of a series of Lp-PLA2-lowering alleles was related to coronary heart...

  15. Prospects for CW and LP operation of the European XFEL in hard X-ray regime

    Energy Technology Data Exchange (ETDEWEB)

    Brinkmann, R.; Schneidmiller, E.A.; Sekutowicz, J.; Yurkov, M.V.

    2014-03-15

    The European XFEL will operate nominally at 17.5 GeV in SP (short pulse) mode with 0.65 ms long bunch train and 10 Hz repetition rate. A possible upgrade of the linac to CW (continuous wave) or LP (long pulse) modes with a corresponding reduction of electron beam energy is under discussion since many years. Recent successes in the dedicated R and D program allow to forecast a technical feasibility of such an upgrade in the foreseeable future. One of the challenges is to provide sub-Aangstrom FEL operation in CW and LP modes. In this paper we perform a preliminary analysis of a possible operation of the European XFEL in the hard X-ray regime in CW and LP modes with the energies of 7 GeV and 10 GeV, respectively. We consider lasing in the baseline XFEL undulator as well as in a new undulator with a reduced period. We show that, with reasonable requirements on electron beam quality, lasing on the fundamental will be possible in sub-Aangstrom regime. As an option for generation of brilliant photon beams at short wavelengths we also consider harmonic lasing that has recently attracted a significant attention.

  16. Anti-podoplanin Monoclonal Antibody LpMab-7 Detects Metastatic Lesions of Osteosarcoma.

    Science.gov (United States)

    Kaneko, Mika K; Oki, Hiroharu; Ogasawara, Satoshi; Takagi, Michiaki; Kato, Yukinari

    2015-06-01

    Osteosarcoma is the most common primary malignant bone tumor and is highly metastatic to the lungs. Therefore, the development of a novel molecular targeting therapy against metastasis of osteosarcoma is necessary. A platelet aggregation-inducing factor, podoplanin/aggrus, is involved in tumor metastasis. Furthermore, podoplanin expression was reported to be involved in the poor prognosis of osteosarcoma patients. However, the association between podoplanin expression and metastasis of osteosarcoma remains unclear because of the lack of highly sensitive anti-podoplanin monoclonal antibodies (MAbs). In this study, we used a novel anti-podoplanin MAb, LpMab-7, which is more sensitive than well-known anti-podoplanin MAbs in immunohistochemistry. Immunohistochemical analysis using LpMab-7 showed that podoplanin expression at primary lesions is observed in 15 out of 16 (93.8%) cases. Furthermore, podoplanin expression at metastatic lesions was higher compared with primary lesions in three out of four (75%) cases with lung metastasis. Because LpMab-7 has high sensitivity against podoplanin, it is expected to be useful for molecular targeting therapy for osteosarcomas.

  17. The Leptospiral Antigen Lp49 is a Two-Domain Protein with Putative Protein Binding Function

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira Giuseppe,P.; Oliveira Neves, F.; Nascimento, A.; Gomes Guimaraes, B.

    2008-01-01

    Pathogenic Leptospira is the etiological agent of leptospirosis, a life-threatening disease that affects populations worldwide. Currently available vaccines have limited effectiveness and therapeutic interventions are complicated by the difficulty in making an early diagnosis of leptospirosis. The genome of Leptospira interrogans was recently sequenced and comparative genomic analysis contributed to the identification of surface antigens, potential candidates for development of new vaccines and serodiagnosis. Lp49 is a membrane-associated protein recognized by antibodies present in sera from early and convalescent phases of leptospirosis patients. Its crystal structure was determined by single-wavelength anomalous diffraction using selenomethionine-labelled crystals and refined at 2.0 Angstroms resolution. Lp49 is composed of two domains and belongs to the all-beta-proteins class. The N-terminal domain folds in an immunoglobulin-like beta-sandwich structure, whereas the C-terminal domain presents a seven-bladed beta-propeller fold. Structural analysis of Lp49 indicates putative protein-protein binding sites, suggesting a role in Leptospira-host interaction. This is the first crystal structure of a leptospiral antigen described to date.

  18. Equivalence of LP Relaxation and Max-Product for Weighted Matching in General Graphs

    CERN Document Server

    Sanghavi, Sujay

    2007-01-01

    Max-product belief propagation is a local, iterative algorithm to find the mode/MAP estimate of a probability distribution. While it has been successfully employed in a wide variety of applications, there are relatively few theoretical guarantees of convergence and correctness for general loopy graphs that may have many short cycles. Of these, even fewer provide exact ``necessary and sufficient'' characterizations. In this paper we investigate the problem of using max-product to find the maximum weight matching in an arbitrary graph with edge weights. This is done by first constructing a probability distribution whose mode corresponds to the optimal matching, and then running max-product. Weighted matching can also be posed as an integer program, for which there is an LP relaxation. This relaxation is not always tight. In this paper we show that \\begin{enumerate} \\item If the LP relaxation is tight, then max-product always converges, and that too to the correct answer. \\item If the LP relaxation is loose, the...

  19. LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor†

    Science.gov (United States)

    Clark, Peter G. K.; Vieira, Lucas C. C.; Tallant, Cynthia; Fedorov, Oleg; Singleton, Dean C.; Rogers, Catherine M.; Monteiro, Octovia P.; Bennett, James M.; Baronio, Roberta; Müller, Susanne; Daniels, Danette L.; Méndez, Jacqui; Knapp, Stefan

    2015-01-01

    Abstract The bromodomain‐containing proteins BRD9 and BRD7 are part of the human SWI/SNF chromatin‐remodeling complexes BAF and PBAF. To date, no selective inhibitor for BRD7/9 has been reported despite its potential value as a biological tool or as a lead for future therapeutics. The quinolone‐fused lactam LP99 is now reported as the first potent and selective inhibitor of the BRD7 and BRD9 bromodomains. Development of LP99 from a fragment hit was expedited through balancing structure‐based inhibitor design and biophysical characterization against tractable chemical synthesis: Complexity‐building nitro‐Mannich/lactamization cascade processes allowed for early structure–activity relationship studies whereas an enantioselective organocatalytic nitro‐Mannich reaction enabled the synthesis of the lead scaffold in enantioenriched form and on scale. This epigenetic probe was shown to inhibit the association of BRD7 and BRD9 to acetylated histones in vitro and in cells. Moreover, LP99 was used to demonstrate that BRD7/9 plays a role in regulating pro‐inflammatory cytokine secretion. PMID:27346896

  20. LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor**

    Science.gov (United States)

    Clark, Peter G K; Vieira, Lucas C C; Tallant, Cynthia; Fedorov, Oleg; Singleton, Dean C; Rogers, Catherine M; Monteiro, Octovia P; Bennett, James M; Baronio, Roberta; Müller, Susanne; Daniels, Danette L; Méndez, Jacqui; Knapp, Stefan; Brennan, Paul E; Dixon, Darren J

    2015-01-01

    The bromodomain-containing proteins BRD9 and BRD7 are part of the human SWI/SNF chromatin-remodeling complexes BAF and PBAF. To date, no selective inhibitor for BRD7/9 has been reported despite its potential value as a biological tool or as a lead for future therapeutics. The quinolone-fused lactam LP99 is now reported as the first potent and selective inhibitor of the BRD7 and BRD9 bromodomains. Development of LP99 from a fragment hit was expedited through balancing structure-based inhibitor design and biophysical characterization against tractable chemical synthesis: Complexity-building nitro-Mannich/lactamization cascade processes allowed for early structure–activity relationship studies whereas an enantioselective organocatalytic nitro-Mannich reaction enabled the synthesis of the lead scaffold in enantioenriched form and on scale. This epigenetic probe was shown to inhibit the association of BRD7 and BRD9 to acetylated histones in vitro and in cells. Moreover, LP99 was used to demonstrate that BRD7/9 plays a role in regulating pro-inflammatory cytokine secretion. PMID:25864491

  1. LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor.

    Science.gov (United States)

    Clark, Peter G K; Vieira, Lucas C C; Tallant, Cynthia; Fedorov, Oleg; Singleton, Dean C; Rogers, Catherine M; Monteiro, Octovia P; Bennett, James M; Baronio, Roberta; Müller, Susanne; Daniels, Danette L; Méndez, Jacqui; Knapp, Stefan; Brennan, Paul E; Dixon, Darren J

    2015-05-18

    The bromodomain-containing proteins BRD9 and BRD7 are part of the human SWI/SNF chromatin-remodeling complexes BAF and PBAF. To date, no selective inhibitor for BRD7/9 has been reported despite its potential value as a biological tool or as a lead for future therapeutics. The quinolone-fused lactam LP99 is now reported as the first potent and selective inhibitor of the BRD7 and BRD9 bromodomains. Development of LP99 from a fragment hit was expedited through balancing structure-based inhibitor design and biophysical characterization against tractable chemical synthesis: Complexity-building nitro-Mannich/lactamization cascade processes allowed for early structure-activity relationship studies whereas an enantioselective organocatalytic nitro-Mannich reaction enabled the synthesis of the lead scaffold in enantioenriched form and on scale. This epigenetic probe was shown to inhibit the association of BRD7 and BRD9 to acetylated histones in vitro and in cells. Moreover, LP99 was used to demonstrate that BRD7/9 plays a role in regulating pro-inflammatory cytokine secretion. © 2015 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

  2. Control Effect of Endophytic Bacterium LP 5 to Cucumber Powdery Mildew%植物内生细菌LP5对黄瓜白粉病的田间防治效果

    Institute of Scientific and Technical Information of China (English)

    郭小英; 刘慧平; 韩巨才

    2011-01-01

    以翠贝为对照药剂,比较了植物内生细菌LP5发酵液对黄瓜白粉病的田间防治效果.结果表明,对照药剂翠贝对黄瓜白粉病的防治效果达88.3%,内生细菌LP5的发酵液对黄瓜白粉病的防治效果这79.4%,显然内生细菌LP5具有较好的防治效果,具有一定的开发应用价值.%Using beth as the contrast agent, the field control effect of fermentation liquor from endophytic bacterium LP5 on cucumber powdery mildew was tested. The control effect of beth on cucumber powdery mildew was 88.3%, the effect of fermentation liquor of LP5 was 79.3%. The result showed that endophytic bacterum LP5 had obvious control effect on cucumber powdery mildew, so it had certain development and application value.

  3. Remarks on the Phragmen-Lindelof theorem for Lp-viscosity solutions of fully nonlinear PDEs with unbounded ingredients

    Directory of Open Access Journals (Sweden)

    Kazushige Nakagawa

    2009-11-01

    Full Text Available The Phragmen-Lindelof theorem for Lp-viscosity solutions of fully nonlinear second order elliptic partial differential equations with unbounded coefficients and inhomogeneous terms is established.

  4. Gas Pipelines, LP and LNG, Published in 2006, 1:12000 (1in=1000ft) scale, Washington County GIS.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Gas Pipelines, LP and LNG dataset, published at 1:12000 (1in=1000ft) scale, was produced all or in part from Field Observation information as of 2006. Data by...

  5. Avian host defense peptides.

    Science.gov (United States)

    Cuperus, Tryntsje; Coorens, Maarten; van Dijk, Albert; Haagsman, Henk P

    2013-11-01

    Host defense peptides (HDPs) are important effector molecules of the innate immune system of vertebrates. These antimicrobial peptides are also present in invertebrates, plants and fungi. HDPs display broad-spectrum antimicrobial activities and fulfill an important role in the first line of defense of many organisms. It is becoming increasingly clear that in the animal kingdom the functions of HDPs are not confined to direct antimicrobial actions. Research in mammals has indicated that HDPs have many immunomodulatory functions and are also involved in other physiological processes ranging from development to wound healing. During the past five years our knowledge about avian HDPs has increased considerably. This review addresses our current knowledge on the evolution, regulation and biological functions of HDPs of birds.

  6. A Defense Budget Primer

    Science.gov (United States)

    1998-12-09

    budget practices. See Appendix D for the actual timetable of congressional action on the FY1999 budget.65 See James V. Saturno , The Appropriations...details, see James V. Saturno , The Appropriations Process and the Congressional69 Budget Act, CRS Report 97-947. Table 6. Milestone Votes on the Defense...James V. Saturno , The74 Appropriations Process and the Congressional Budget Act, CRS Report 97-947. The Budget Enforcement Act of 1990 and subsequent

  7. 76 FR 65186 - Request for Public Comments on How the Department of Defense Can Improve the Way It Procures...

    Science.gov (United States)

    2011-10-20

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF DEFENSE Request for Public Comments on How the Department of Defense Can Improve the Way It Procures Defense Items... program is an important instrument of U.S foreign policy. It allows the United States to provide...

  8. IS30-related transposon mediated insertional inactivation of bile salt hydrolase (bsh1) gene of Lactobacillus plantarum strain Lp20.

    Science.gov (United States)

    Kumar, Rajesh; Grover, Sunita; Kaushik, Jai K; Batish, Virender Kumar

    2014-01-01

    Lactobacillus plantarum is a flexible and versatile microorganism that inhabits a variety of niches, and its genome may express up to four bsh genes to maximize its survival in the mammalian gut. However, the ecological significance of multiple bsh genes in L. plantarum is still not clearly understood. Hence, this study demonstrated the disruption of bile salt hydrolase (bsh1) gene due to the insertion of a transposable element in L. plantarum Lp20 - a wild strain of human fecal origin. Surprisingly, L. plantarum strain Lp20 produced a ∼2.0 kb bsh1 amplicon against the normal size (∼1.0 kb) bsh1 amplicon of Bsh(+)L. plantarum Lp21. Strain Lp20 exhibited minimal Bsh activity in spite of having intact bsh2, bsh3 and bsh4 genes in its genome and hence had a Bsh(-) phenotype. Cloning and sequence characterization of Lp20 bsh1 gene predicted four individual open reading frames (ORFs) within this region. BLAST analysis of ORF1 and ORF2 revealed significant sequence similarity to the L. plantarum bsh1 gene while ORF3 and ORF4 showed high sequence homology to IS30-family transposases. Since, IS30-related transposon element was inserted within Lp20 bsh1 gene in reverse orientation (3'-5'), it introduced several stop codons and disrupted the protein reading frames of both Bsh1 and transposase. Inverted terminal repeats (GGCAGATTG) of transposon, mediated its insertion at 255-263 nt and 1301-1309 nt positions of Lp20 bsh1 gene. In conclusion, insertion of IS30 related-transposon within the bsh1 gene sequence of L. plantarum strain Lp20 demolished the integrity and functionality of Bsh1 enzyme. Additionally, this transposon DNA sequence remains active among various Lactobacillus spp. and hence harbors the potential to be explored in the development of efficient insertion mutagenesis system.

  9. Plant Defense against Insect Herbivores

    Science.gov (United States)

    Fürstenberg-Hägg, Joel; Zagrobelny, Mika; Bak, Søren

    2013-01-01

    Plants have been interacting with insects for several hundred million years, leading to complex defense approaches against various insect feeding strategies. Some defenses are constitutive while others are induced, although the insecticidal defense compound or protein classes are often similar. Insect herbivory induce several internal signals from the wounded tissues, including calcium ion fluxes, phosphorylation cascades and systemic- and jasmonate signaling. These are perceived in undamaged tissues, which thereafter reinforce their defense by producing different, mostly low molecular weight, defense compounds. These bioactive specialized plant defense compounds may repel or intoxicate insects, while defense proteins often interfere with their digestion. Volatiles are released upon herbivory to repel herbivores, attract predators or for communication between leaves or plants, and to induce defense responses. Plants also apply morphological features like waxes, trichomes and latices to make the feeding more difficult for the insects. Extrafloral nectar, food bodies and nesting or refuge sites are produced to accommodate and feed the predators of the herbivores. Meanwhile, herbivorous insects have adapted to resist plant defenses, and in some cases even sequester the compounds and reuse them in their own defense. Both plant defense and insect adaptation involve metabolic costs, so most plant-insect interactions reach a stand-off, where both host and herbivore survive although their development is suboptimal. PMID:23681010

  10. Plant defense against insect herbivores

    DEFF Research Database (Denmark)

    Fürstenberg-Hägg, Joel; Zagrobelny, Mika; Bak, Søren

    2013-01-01

    have adapted to resist plant defenses, and in some cases even sequester the compounds and reuse them in their own defense. Both plant defense and insect adaptation involve metabolic costs, so most plant-insect interactions reach a stand-off, where both host and herbivore survive although......Plants have been interacting with insects for several hundred million years, leading to complex defense approaches against various insect feeding strategies. Some defenses are constitutive while others are induced, although the insecticidal defense compound or protein classes are often similar....... Insect herbivory induce several internal signals from the wounded tissues, including calcium ion fluxes, phosphorylation cascades and systemic- and jasmonate signaling. These are perceived in undamaged tissues, which thereafter reinforce their defense by producing different, mostly low molecular weight...

  11. DEFENSE PROGRAMS RISK MANAGEMENT FRAMEWORK

    Directory of Open Access Journals (Sweden)

    Constantin PREDA

    2012-01-01

    Full Text Available For the past years defense programs have faced delays in delivering defense capabilities and budget overruns. Stakeholders are looking for ways to improve program management and the decision making process given the very fluid and uncertain economic and political environment. Consequently, they have increasingly resorted to risk management as the main management tool for achieving defense programs objectives and for delivering the defense capabilities strongly needed for the soldiers on the ground on time and within limited defense budgets. Following a risk management based decision-making approach the stakeholders are expected not only to protect program objectives against a wide range of risks but, at the same time, to take advantage of the opportunities to increase the likelihood of program success. The prerequisite for making risk management the main tool for achieving defense programs objectives is the design and implementation of a strong risk management framework as a foundation providing an efficient and effective application of the best risk management practices. The aim of this paper is to examine the risk management framework for defense programs based on the ISO 31000:2009 standard, best risk management practices and the defense programs’ needs and particularities. For the purposes of this article, the term of defense programs refers to joint defense programs.

  12. Identification of a new sucrose transporter in rye-grass (LpSUT2): effect of defoliation and putative fructose sensing.

    Science.gov (United States)

    Berthier, Alexandre; Meuriot, Frédéric; Dédaldéchamp, Fabienne; Lemoine, Rémi; Prud'homme, Marie-Pascale; Noiraud-Romy, Nathalie

    2014-11-01

    Rye-grass fast regrowth after defoliation results from an efficient mobilization of C reserves which are transported as sucrose towards regrowing leaves, and which can be supported by one or several sucrose transporters (SUTs) like LpSUT1. Therefore, our objectives were to isolate, identify, characterize and immunolocalize such sucrose transporters. A protein (LpSUT2) showing a twelve spanning trans-membrane domain, extended N terminal and internal cytoplasmic loop, and kinetic properties consistent with well-known sucrose transporters, was isolated and successfully characterized. Along with LpSUT1, it was mainly localized in mesophyll cells of leaf sheaths and elongating leaf bases. These transporters were also found in parenchyma bundle sheath (PBS) cells but they were not detected in the sieve element/companion cell complex of the phloem. Unlike LpSUT1 transcript levels which increased as a response to defoliation in source and sink tissues, LpSUT2 transcript levels were unaffected by defoliation and weakly expressed. Interestingly, sucrose transport by LpSUT2 was inhibited by fructose. LpSUT1 and LpSUT2 appeared to have different functions. LpSUT1 is proposed to play a key role in C storage and mobilization by allowing sucrose transport between PBS and mesophyll cells, depending on the plant C status. LpSUT2 could be involved in sucrose/fructose sensing at sub-cellular level. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  13. Synthetic Plant Defense Elicitors

    Directory of Open Access Journals (Sweden)

    Yasemin eBektas

    2015-01-01

    Full Text Available To defend themselves against invading pathogens plants utilize a complex regulatory network that coordinates extensive transcriptional and metabolic reprogramming. Although many of the key players of this immunity-associated network are known, the details of its topology and dynamics are still poorly understood. As an alternative to forward and reverse genetic studies, chemical genetics-related approaches based on bioactive small molecules have gained substantial popularity in the analysis of biological pathways and networks. Use of such molecular probes can allow researchers to access biological space that was previously inaccessible to genetic analyses due to gene redundancy or lethality of mutations. Synthetic elicitors are small drug like molecules that induce plant defense responses, but are distinct from known natural elicitors of plant immunity. While the discovery of the some synthetic elicitors had already been reported in the 1970s, recent breakthroughs in combinatorial chemical synthesis now allow for inexpensive high-throughput screens for bioactive plant defense-inducing compounds. Along with powerful reverse genetics tools and resources available for model plants and crop systems, comprehensive collections of new synthetic elicitors will likely allow plant scientists to study the intricacies of plant defense signaling pathways and networks in an unparalleled fashion. As synthetic elicitors can protect crops from diseases, without the need to be directly toxic for pathogenic organisms, they may also serve as promising alternatives to conventional biocidal pesticides, which often are harmful for the environment, farmers and consumers. Here we are discussing various types of synthetic elicitors that have been used for studies on the plant immune system, their modes-of-action as well as their application in crop protection.

  14. Nanomaterials for Defense Applications

    Science.gov (United States)

    Turaga, Uday; Singh, Vinitkumar; Lalagiri, Muralidhar; Kiekens, Paul; Ramkumar, Seshadri S.

    Nanotechnology has found a number of applications in electronics and healthcare. Within the textile field, applications of nanotechnology have been limited to filters, protective liners for chemical and biological clothing and nanocoatings. This chapter presents an overview of the applications of nanomaterials such as nanofibers and nanoparticles that are of use to military and industrial sectors. An effort has been made to categorize nanofibers based on the method of production. This chapter particularly focuses on a few latest developments that have taken place with regard to the application of nanomaterials such as metal oxides in the defense arena.

  15. Phenomenon of Psychological Defense

    Directory of Open Access Journals (Sweden)

    Elena T. Sokolova

    2011-01-01

    Full Text Available The author discusses the controversial issues of formation and functioning of psy¬chological defense mechanisms in ontogenesis and in personality disorders as they are represented in classical and contemporary psychoanalysis, in cognitivism and communication theory. The paper emphasizes the role of cognitive organi¬zation (style, sign-symbolic mediation, representative system of object relations and attachments in individual typological variability of the level organization of ciency of personal and social adaptation, in maturity and mental health of personality

  16. Defensive engagement and perceptual enhancement

    OpenAIRE

    Keil, Andreas; Bradley, Margaret M; Ihssen, Niklas; Heim, Sabine; Vila, Jaime; Guerra, Pedro; Lang, Peter J.

    2010-01-01

    We tested whether visual cortical sensitivity to external cues in the context of an acute defensive reaction is heightened or attenuated. A strong cardiac defense (fear) response was elicited by presenting an abrupt, loud acoustic stimulus following a 10-minute period of quiescence. Electrocortical responses to aversive and neutral pictures following defensive stimulus onset were measured using dense-array EEG. Pictures were flickered at 12.5 Hz to evoke steady-state visual evoked potentials ...

  17. Ballistic Missile Defense System (BMDS)

    Science.gov (United States)

    2015-12-01

    Estimate RDT&E - Research , Development, Test, and Evaluation SAR - Selected Acquisition Report SCP - Service Cost Position TBD - To Be Determined TY - Then...all ranges and in all phases of flight. Following guidance from the President, the Secretary of Defense approved the Ballistic Missile Defense (BMD...based Midcourse Defense (GMD) system to enhance our capability against Intercontinental Ballistic Missiles. We are currently sustaining 30

  18. 兰博基尼发布AventadorLP 700—4敞篷版

    Institute of Scientific and Technical Information of China (English)

    2013-01-01

    2012年11月12日,圣亚加塔·波隆尼兰博基尼汽车有限公司正式推出新款兰博基尼Avenmdor LP700—4敞篷版。这款兰博基尼品牌史上最激动人心的产品的问世,树立了世界豪华超级跑车敞篷系列的全新标杆。

  19. 强悍小牛 全新 Huracan LP610-4

    Institute of Scientific and Technical Information of China (English)

    Lee

    2014-01-01

    从2003年日内瓦车展上首次亮相到现在,兰博基尼Gallardo服役己十年有余。十年的领跑风潮,总产量达14022辆,Gallardo己成为了兰博基尼史上最成功的车型。十年之后,兰博基尼推出了Gallardo的继任者,全新HuracanLP6IO-4o

  20. Nonlinear optics in the LP(02) higher-order mode of a fiber.

    Science.gov (United States)

    Chen, Y; Chen, Z; Wadsworth, W J; Birks, T A

    2013-07-29

    The distinct disperion properties of higher-order modes in optical fibers permit the nonlinear generation of radiation deeper into the ultraviolet than is possible with the fundamental mode. This is exploited using adiabatic, broadband mode convertors to couple light efficiently from an input fundamental mode and also to return the generated light to an output fundamental mode over a broad spectral range. For example, we generate visible and UV supercontinuum light in the LP(02) mode of a photonic crystal fiber from sub-ns pulses with a wavelength of 532 nm.

  1. Very deep images of the disc around beta Pictoris at Lp

    Science.gov (United States)

    Milli, J.; Absil, O.; Mouillet, D.; Lagrange, A.-M.; Boccaletti, A.; Girard, J.; Mawet, D.; Augereau, J.-C.

    2014-09-01

    We present observations of the innermost regions of the disc around beta Pictoris performed with VLT/NaCo in the Lp band. We combined seven deep datasets to retrieve the morphology of the disc down to 0.1arcsec. Our observations reveal intriguing ripples in the midplane of the disk at 0.5arcsec, as well as an overall bow of the disc spine, compatible with a disc slightly inclined with respect to edge-on scattering light anisotropically. Modelling suggests the presence of dust down to 10AU in order to explain the bright flux seen below 0.5 arcsec.

  2. Role of microbial adhesion in phenanthrene biodegradation by Pseudomonas fluorescens LP6a

    Science.gov (United States)

    Abbasnezhad, Hassan

    Biodegradation of poorly water soluble hydrocarbons, such as n-alkanes and polycyclic aromatic hydrocarbons (PAHs) is often limited by the low availability of the pollutant to microbes. Adhesion of microorganisms to the oil-water interface can influence this availability. Our approach was to study a range of compounds and mechanisms to promote the adhesion of a hydrophilic PAH degrading bacterium, Pseudomonas fluorescens LP6a, to an oil-water interface and examine the effect on biodegradation of phenanthrene by the bacteria. The cationic surfactants cetylpyridinium chloride (CPC), poly-L-lysine and chlorhexidine gluconate (CHX) and the long chain alcohols 1-dodecanol, 2-dodecanol and farnesol increased the adhesion of P. fluorescens LP6a to n-hexadecane from ca. 30% to ca. 90% of suspended cells adhering. The alcohols also caused a dramatic change in the oil-water contact angle of the cell surface, increasing it from 24° to 104°, whereas the cationic compounds had little effect. In contrast, cationic compounds changed the electrophoretic mobility of the bacteria, reducing the mean zeta potential from --23 to --7 mV in 0.01M potassium phosphate buffer, but the alcohols had no effect on zeta potential. This results illustrate that alcohols acted through altering the cell surface hydrophobicity, whereas cationic surfactants changed the surface charge density. Phenanthrene was dissolved in heptamethylnonane and introduced to the aqueous growth medium, hence forming a two phase system. Introducing 1-dodecanol at concentrations of 217, 820 or 4100 mg/L resulted in comparable increases in phenanthrene biodegradation of about 30% after 120 h incubation with non-induced cultures. After 100 h of incubation with LP6a cultures induced with 2-aminobenzoate, 4.5% of the phenanthrene was mineralized by cultures versus more than 10% by the cultures containing initial 1-dodecanol or 2-dodecanol concentrations of 120 or 160 mg/L. The production and accumulation of metabolites in

  3. LP-211 is a brain penetrant selective agonist for the serotonin 5-HT7 receptor

    OpenAIRE

    Hedlund, Peter B.; Leopoldo, Marcello; Caccia, Silvio; Sarkisyan, Gor; Fracasso, Claudia; Martelli, Giuliana; Lacivita, Enza; Berardi, Francesco; Perrone, Roberto

    2010-01-01

    We have determined the pharmacological profile of the new serotonin 5-HT7 receptor agonist N-(4-cyanophenylmethyl)-4-(2-diphenyl)-1-piperazinehexanamide (LP-211). Radioligand binding assays were performed on a panel of 5-HT receptor subtypes. The compound was also evaluated in vivo by examining its effect on body temperature regulation in mice lacking the 5-HT7 receptor (5-HT7−/−) and their 5-HT7+/+ sibling controls. Disposition studies were performed in mice of both genotypes. It was found t...

  4. 蛮牛进化论:Lamborghini Murcielago LP640

    Institute of Scientific and Technical Information of China (English)

    雪凝; 老车(图)

    2006-01-01

    兰博基尼在第76届日内瓦车展上推出一款Murclelago的延伸车LP640。该车不仅外观有新变化,而且还重新调校了发动机的动力输出,力求其输出功率维持在超级跑车水准之上,得以与其它新车款相抗衡。

  5. Some extremal properties of multivariate polynomial splines in the metric Lp (Rd )

    Institute of Scientific and Technical Information of China (English)

    刘永平; 许贵桥

    2001-01-01

    We constructed a kind of continuous multivariate spline operators as the approximation tools of the multivariate functions on the Bd instead of the usual multivariate cardinal interpolation oper-ators of splines, and obtained the approximation error by this kind of spline operators. Meantime, by the results, we also obtained that the spaces of multivariate polynomial splines are weakly asymptoti-cally optimal for the Kolmogorov widths and the linear widths of some anisotropic Sobolev classes of smooth functions on Bd in the metric Lp(Bd).

  6. Laser polarimeter LP101M and its applications in liquid cromatography

    Science.gov (United States)

    Fajer, V.; Rodriguez, C.; Gonzalez, R.; Cossio, G.; Martinez, M.; Bravo, O.

    1996-02-01

    A high sensitivity laser polarimeter LP101M employing a He-Ne laser has been designed and constructed as a detector for liquid chromatography achieving a sensitivity better than 0.001 degree. The operation principle and technical characteristics of this instrument are described. A liquid gel chromatography column system suitable for sugar cane juice analysis was also designed and calibrated. It separated and analyzed the medium molecular weight carbohydrates and demonstrated the strong influence of these substances in the conventional polarimetric determinations.

  7. U.S. National Defense Acquisition and Budgetary Policy in an International Perspective

    Science.gov (United States)

    2011-12-03

    rarely , if ever, large enough to produce this effect (Hale, 1987). As a consequence, it is a general rule that the more units produced, the lower will...defense-industrial independence. Although licensed manufacturing transfers the know-how to build products, it rarely transfers the tacit knowledge...defense policy: Medium power, even bigger ambitions? Korean Journal of Defense Analysis, 22(2), 183–96. Berghezan, G., & Richard, P. (2002). Israël, terre

  8. An alternative physiological role for the EmhABC efflux pump in Pseudomonas fluorescens cLP6a

    Directory of Open Access Journals (Sweden)

    Adebusuyi Abigail A

    2011-11-01

    Full Text Available Abstract Background Efflux pumps belonging to the resistance-nodulation-division (RND superfamily in bacteria are involved in antibiotic resistance and solvent tolerance but have an unknown physiological role. EmhABC, a RND-type efflux pump in Pseudomonas fluorescens strain cLP6a, extrudes hydrophobic antibiotics, dyes and polycyclic aromatic hydrocarbons including phenanthrene. The effects of physico-chemical factors such as temperature or antibiotics on the activity and expression of EmhABC were determined in order to deduce its physiological role(s in strain cLP6a in comparison to the emhB disruptant strain, cLP6a-1. Results Efflux assays conducted with 14C-phenanthrene showed that EmhABC activity is affected by incubation temperature. Increased phenanthrene efflux was measured in cLP6a cells grown at 10°C and decreased efflux was observed at 35°C compared with cells grown at the optimum temperature of 28°C. Membrane fatty acids in cLP6a cells were substantially altered by changes in growth temperature and in the presence of tetracycline. Changed membrane fatty acids and increased membrane permeability were associated with ~30-fold increased expression of emhABC in cLP6a cells grown at 35°C, and with increased extracellular free fatty acids. Growth of P. fluorescens cLP6a at supra-optimal temperature was enhanced by the presence of EmhABC compared to strain cLP6a-1. Conclusions Combined, these observations suggest that the EmhABC efflux pump may be involved in the management of membrane stress effects such as those due to unfavourable incubation temperatures. Efflux of fatty acids replaced as a result of membrane damage or phospholipid turnover may be the primary physiological role of the EmhABC efflux pump in P. fluorescens cLP6a.

  9. G 207-9 and LP 133-144: light-curve analysis and asteroseismology of two ZZ Ceti stars

    Science.gov (United States)

    Bognár, Zs.; Paparó, M.; Molnár, L.; Pápics, P. I.; Plachy, E.; Verebélyi, E.; Sódor, Á.

    2016-10-01

    G 207-9 and LP 133-144 are two rarely observed ZZ Ceti stars located in the middle and close to the blue edge of the ZZ Ceti instability domain, respectively. We aimed to observe them at least during one observing season at Konkoly Observatory with the purpose of extending the list of known pulsation modes for asteroseismic investigations and detect any significant changes in their pulsational behaviour. We determined five and three new normal modes of G 207-9 and LP 133-144, respectively. In LP 133-144, our frequency analysis also revealed that at least at three modes there are actually triplets with frequency separations of ˜ 4 μHz. The rotational period of LP 133-144 based on the triplets is ≃42 h. The preliminary asteroseismic fits of G 207-9 predict Teff = 12 000 or 12 400 K and M_{ast }=0.855-0.870 M_{⊙} values for the effective temperature and mass of the star, depending on the assumptions on the spherical degree (l) values of the modes. These results are in agreement with the spectroscopic determinations. In the case of LP 133-144, the best-fitting models prefer Teff = 11 800 K in effective temperature and M* ≥ 0.71 M⊙ stellar masses, which are more than 0.1 M⊙ larger than the spectroscopic value.

  10. Antioxidant and inflammatory aspects of lipoprotein-associated phospholipase A2 (Lp-PLA2 : a review

    Directory of Open Access Journals (Sweden)

    Damasceno Nágila RT

    2011-09-01

    Full Text Available Abstract The association of cardiovascular events with Lp-PLA2 has been studied continuously today. The enzyme has been strongly associated with several cardiovascular risk markers and events. Its discovery was directly related to the hydrolysis of the platelet-activating factor and oxidized phospholipids, which are considered protective functions. However, the hydrolysis of bioactive lipids generates lysophospholipids, compounds that have a pro-inflammatory function. Therefore, the evaluation of the distribution of Lp-PLA2 in the lipid fractions emphasized the dual role of the enzyme in the inflammatory process, since the HDL-Lp-PLA2 enzyme contributes to the reduction of atherosclerosis, while LDL-Lp-PLA2 stimulates this process. Recently, it has been verified that diet components and drugs can influence the enzyme activity and concentration. Thus, the effects of these treatments on Lp-PLA2 may represent a new kind of prevention of cardiovascular disease. Therefore, the association of the enzyme with the traditional assessment of cardiovascular risk may help to predict more accurately these diseases.

  11. PAEK增韧LP-15聚酰亚胺树脂体系性能研究%Study on the Performance of PAEK Toughened LP-15 Polyimide Resin System

    Institute of Scientific and Technical Information of China (English)

    熊磊; 张佐光; 李小刚; 李宏运; 益小苏

    2006-01-01

    选用了高性能的热塑性聚合物PAEK对LP-15聚酰亚胺进行增韧,研究了在不同含量下PAEK对LP-15聚酰亚胺性能的影响.实验结果表明,两者共混后,树脂体系保持了较高的玻璃化转变温度(Tg),而冲击强度和弯曲强度也得到了明显的提高.同时,以LP-15/PAEK为基体的复合材料在抗冲击性能方面亦有了明显的改善.

  12. Multi-parameter singular Radon transforms II: the L^p theory

    CERN Document Server

    Stein, Elias M

    2011-01-01

    The purpose of this paper is to study the $L^p$ boundedness of operators of the form \\[ f\\mapsto \\psi(x) \\int f(\\gamma_t(x))K(t)\\: dt, \\] where $\\gamma_t(x)$ is a $C^\\infty$ function defined on a neighborhood of the origin in $(t,x)\\in \\R^N\\times \\R^n$, satisfying $\\gamma_0(x)\\equiv x$, $\\psi$ is a $C^\\infty$ cutoff function supported on a small neighborhood of $0\\in \\R^n$, and $K$ is a "multi-parameter singular kernel" supported on a small neighborhood of $0\\in \\R^N$. We also study associated maximal operators. The goal is, given an appropriate class of kernels $K$, to give conditions on $\\gamma$ such that every operator of the above form is bounded on $L^p$ ($1

  13. Prediction of Losses in Flow Through the Last Stage of LP Steam Turbine

    Institute of Scientific and Technical Information of China (English)

    S. Dykas; W. Wróblewski; H. (L)ukowicz; T. Chmielniak

    2007-01-01

    The aim of presented work was the prediction of the losses in the wet steam flow through the last stage of 200MW steam turbine LP part. To this end, three numerical tools were used. The first method was the streamline curvature method (SCM) used on the meridional plane with losses correlations. The next two methods, TASCflow commercial CFD code and an in-house CFD code, based on the solution of the Reynoldsaveraged Navier-Stokes equations (RANS). Application of three independent numerical tools allowed to make the more reliable losses analysis and made possible to compare applied numerical methods with each other. For the flow modeling in the last stage of LP steam turbine the various two-phase flow models were used and compared. The equilibrium model and non-equilibrium models with homogeneous and/or heterogeneous condensation were considered. The boundary conditions at the inlet and outlet from the stage were selected in such way to get the beginning of the homogeneous condensation process in the stator. It corresponded to the part load of the turbine, i. e. 140MW power and pressure in condenser 2.7kPa.

  14. An LP-based heuristic for the fixed charge transportation problem

    DEFF Research Database (Denmark)

    Klose, Andreas

    2007-01-01

    The fixed charge transportation problem consists in finding a minimum cost network flow from a set of suppliers to a set of customers. Beside costs proportional to quantities transported, transportation costs also include a fixed charge. The paper describes a linear programming based heuristic ap...... inequalities and flow cover inequalities, the approach also employs Fenchel cuts that are based on embedded 0-1 single node flow sets. Computational results obtained for a set of standard test problem instances are reported.......The fixed charge transportation problem consists in finding a minimum cost network flow from a set of suppliers to a set of customers. Beside costs proportional to quantities transported, transportation costs also include a fixed charge. The paper describes a linear programming based heuristic...... approach for computing lower and upper bounds on the minimal cost. To this end, the LP relaxation is iteratively strengthened by means of adding cuts; in each iteration the current LP solution is then used to guide a local search heuristic. In addition to standard polyhedral cuts as lifted cover...

  15. The Relationship between Inflation and Defense Expenditures.

    Science.gov (United States)

    1979-12-01

    resources they would be bid up in the expanding sector. See Robert Solow , "Evaluation," in After the Phillips Curve: Persistence of High Inflation and...can be explained by the respective rates of growth of money supply per unit of national product. ’𔃼 IF’risch, op. cit., p. 1311. Robert J. Gordon...Statistical Approach for Forecasting Defense Expenditures in the Short-run," in William F. Butler, Robert A. Kavesh, and Robert B. Platt, eds., "Methods and

  16. 75 FR 22203 - Delegation of Certain Functions Under Section 1265 of the National Defense Authorization Act for...

    Science.gov (United States)

    2010-04-28

    ... Functions Under Section 1265 of the National Defense Authorization Act for Fiscal Year 2010 Memorandum for... the United States, including section 301 of title 3, United States Code, I hereby delegate to you the functions and authority conferred upon the President by section 1265 of the National Defense...

  17. Defense Management: More Reliable Cost Estimates and Further Planning Needed to Inform the Marine Corps Realignment Initiatives in the Pacific

    Science.gov (United States)

    2013-06-01

    remaining on Okinawa. Page 16 GAO-13-360 Defense Management Carrier Air Wing 5, a Navy unit paired with the aircraft carrier USS George...The Honorable Thad Cochran Ranking Member Subcommittee on Defense Committee on Appropriations United States Senate The Honorable Tim Johnson

  18. 76 FR 4322 - Availability of the Fiscal Year 2009 Missile Defense Agency Services Contracts Inventory Pursuant...

    Science.gov (United States)

    2011-01-25

    ... of the Secretary Availability of the Fiscal Year 2009 Missile Defense Agency Services Contracts... United States Code as amended by the National Defense Authorization Act for Fiscal Year 2008 (NDAA 08... Procurement and Acquisition Policy, Office of Strategic Sourcing (DPAP/SS) will make available to the public...

  19. 76 FR 78874 - Defense Federal Acquisition Regulation Supplement: Title 41 Positive Law Codification-Further...

    Science.gov (United States)

    2011-12-20

    ... Positive Law Codification--Further Implementation (DFARS Case 2012- D003) AGENCIES: Defense Acquisition... Defense Federal Acquisition Regulation Supplement to conform statutory titles to the new Positive Law Codification of Title 41, United States Code, ``Public Contracts.'' DATES: Comment Date: Comments on the...

  20. European Missile Defense and Russia

    Science.gov (United States)

    2014-07-01

    most senior level—the only one that matters in Russian decisionmaking cul - ture—is also of significance today and will also be re- ferred to later in... org /missile-defense/us-ballistic-missile-defense/p30607. 9. Email exchange with author, July 2013. 10. “Safeguard,” Washington, DC: Federation of Ameri

  1. 32 CFR 516.54 - Witnesses for the United States.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Witnesses for the United States. 516.54 Section 516.54 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS LITIGATION Release of Information and Appearance of Witnesses Scope Status, Travel, and Expenses of Witnesses §...

  2. Plant defense against insect herbivores

    DEFF Research Database (Denmark)

    Fürstenberg-Hägg, Joel; Zagrobelny, Mika; Bak, Søren

    2013-01-01

    defense responses. Plants also apply morphological features like waxes, trichomes and latices to make the feeding more difficult for the insects. Extrafloral nectar, food bodies and nesting or refuge sites are produced to accommodate and feed the predators of the herbivores. Meanwhile, herbivorous insects......Plants have been interacting with insects for several hundred million years, leading to complex defense approaches against various insect feeding strategies. Some defenses are constitutive while others are induced, although the insecticidal defense compound or protein classes are often similar....... Insect herbivory induce several internal signals from the wounded tissues, including calcium ion fluxes, phosphorylation cascades and systemic- and jasmonate signaling. These are perceived in undamaged tissues, which thereafter reinforce their defense by producing different, mostly low molecular weight...

  3. TRAC-PF1/MOD1 post-test calculations of the OECD LOFT Experiment LP-SB-3

    Energy Technology Data Exchange (ETDEWEB)

    Allen, E J; Neill, A P [UKAEA Atomic Energy Establishment, Winfrith (UK)

    1990-04-01

    Analysis of the small, cold leg break, OECD LOFT Experiment LP-SB-3 using the best-estimate computer code TRAC-PF1/MOD1 is presented. Descriptions of the LOFT facility and the LP-SB-3 experiment are given and development of the TRAC-PF1/MOD1 input model is detailed. The calculations performed in achieving the steady state conditions, from which the experiment was initiated, and the specification of experimental boundary conditions are outlined. Results of the TRAC-PF1/MOD1 calculation are found to be generally consistent with those reported, by members of the OECD LOFT Program Review Group, in the LP-SB-3 Comparison Report.'' Overall trends with respect to pressure histories, minimum primary system mass inventory and accumulator behaviour are reasonably well reproduced by TRAC-PF1/MOD1. 17 refs., 26 figs., 3 tabs.

  4. Structural Analysis of LP-CM Facing Heat Flux in Tokamak and Evaluation of Stress Field and Displacement Field

    Directory of Open Access Journals (Sweden)

    Huang-bin Lin

    2012-01-01

    Full Text Available Langmuir Probes attached to plasma-facing components in a Tokamak are used to diagnose high-temperature plasma during fusion experiments. In this work, a finite element model of Langmuir Probe-Cooling Monoblock (LP-CM is established, and structural analysis of the LP-CM is carried out. The maximum von Mises stress during the 400 s incident heat flux has been given in detail, and the relationship between the sliding friction coefficient and thermal stress has been investigated systematically. A contact design is employed between Langmuir Probe and Cooling Monoblock, which is an effective method to lower the thermal stress. The thermal stress reaches the peak on the edge of the aluminium oxide ceramic interlayer. The damaged displacement field of the LP-CM has been examined fully, and the maximum global displacement is 0.444 mm.

  5. Morphine increases hippocampal viral load and suppresses frontal lobe CCL5 expression in the LP-BM5 AIDS model.

    Science.gov (United States)

    McLane, Virginia D; Cao, Ling; Willis, Colin L

    2014-04-15

    Chronic opiate abuse accelerates the development of cognitive deficits in human immunodeficiency virus (HIV)-1 patients. To investigate morphine's effects on viral infection of the central nervous system, we applied chronic morphine treatment to the LP-BM5 murine acquired immunodeficiency syndrome (MAIDS) model. LP-BM5 infection induces proinflammatory cytokine/chemokine production, correlating to increased blood-brain barrier permeability. Morphine treatment significantly increased LP-BM5 viral load in the hippocampus, but not in the frontal lobe. Morphine reduced the chemokine CCL5 to non-infected levels in the frontal lobe, but not in the hippocampus. These data indicate a region-specific mechanism for morphine's effects on virally-induced neurocognitive deficits.

  6. Chemical and Biological Defense Program Annual Report to Congress

    Science.gov (United States)

    2006-03-01

    state public health systems, to expand existing biosurveillance efforts, and to fund research on medical countermeasures against potential bioterror...Detection System (JBSDS) • Joint Portal Shield • Biological Identification System (BIDS) • Dry Filter Units (DFUs) Table 2-3 Biological Defense...Detection System (BIDS) • Joint Portal Shield Network Sensor System • Automated biological remote detection and early warning capabilities

  7. Defensive Federal Litigation

    Science.gov (United States)

    1998-08-20

    Unidos , Inc. v. United States Dep’t of Labor, 803 F.2d 1063, 1068 (9th Cir. 1986); Ameron, Inc. v. United States Army Corps of Eng’rs, 787 F.2d 875 (3d...Federal Circuit 59Diekan v. Stone, 995 F.2d 1061 (1st Cir. 1993); Penagaricano v. Llenza, 747 F.2d 55 (1st Cir. 1984); Guerra v. Scruggs, 942 F.2d 270

  8. Genome-wide association study of Lp-PLA(2 activity and mass in the Framingham Heart Study.

    Directory of Open Access Journals (Sweden)

    Sunil Suchindran

    2010-04-01

    Full Text Available Lipoprotein-associated phospholipase A(2 (Lp-PLA(2 is an emerging risk factor and therapeutic target for cardiovascular disease. The activity and mass of this enzyme are heritable traits, but major genetic determinants have not been explored in a systematic, genome-wide fashion. We carried out a genome-wide association study of Lp-PLA(2 activity and mass in 6,668 Caucasian subjects from the population-based Framingham Heart Study. Clinical data and genotypes from the Affymetrix 550K SNP array were obtained from the open-access Framingham SHARe project. Each polymorphism that passed quality control was tested for associations with Lp-PLA(2 activity and mass using linear mixed models implemented in the R statistical package, accounting for familial correlations, and controlling for age, sex, smoking, lipid-lowering-medication use, and cohort. For Lp-PLA(2 activity, polymorphisms at four independent loci reached genome-wide significance, including the APOE/APOC1 region on chromosome 19 (p = 6 x 10(-24; CELSR2/PSRC1 on chromosome 1 (p = 3 x 10(-15; SCARB1 on chromosome 12 (p = 1x10(-8 and ZNF259/BUD13 in the APOA5/APOA1 gene region on chromosome 11 (p = 4 x 10(-8. All of these remained significant after accounting for associations with LDL cholesterol, HDL cholesterol, or triglycerides. For Lp-PLA(2 mass, 12 SNPs achieved genome-wide significance, all clustering in a region on chromosome 6p12.3 near the PLA2G7 gene. Our analyses demonstrate that genetic polymorphisms may contribute to inter-individual variation in Lp-PLA(2 activity and mass.

  9. Insertion of apoLp-III into a lipid monolayer is more favorable for saturated, more ordered, acyl-chains

    Energy Technology Data Exchange (ETDEWEB)

    Rathnayake, Sewwandi S. [Kent State Univ., Kent, OH (United States); Mirheydari, Mona [Kent State Univ., Kent, OH (United States); Schulte, Adam [Kent State Univ., Kent, OH (United States); Gillahan, James E. [Kent State Univ., Kent, OH (United States); Gentit, Taylor [Kent State Univ., Kent, OH (United States); Phillips, Ashley N. [Kent State Univ., Kent, OH (United States); Okonkwo, Rose K. [Kent State Univ., Kent, OH (United States); Burger, Koert N.J. [Utrecht Univ. (Netherlands); Mann, Elizabeth K. [Kent State Univ., Kent, OH (United States); Vaknin, David [Ames Lab., Ames, IA (United States); Bu, Wei [Ames Lab., Ames, IA (United States); Agra-Kooijman, Dena Mae [Kent State Univ., Kent, OH (United States); Kooijman, Edgar E. [Kent State Univ., Kent, OH (United States)

    2013-10-04

    Neutral lipid transport in mammals is complicated involving many types of apolipoprotein. The exchangeable apolipoproteins mediate the transfer of hydrophobic lipids between tissues and particles, and bind to cell surface receptors. Amphipathic a-helices form a common structural motif that facilitates their lipid binding and exchangeability. ApoLp-III, the only exchangeable apolipoprotein found in insects, is a model amphipathic a:helix bundle protein and its three dimensional structure and function mimics that of the mammalian proteins apoE and apoAI. Even the intracellular exchangeable lipid droplet protein TIP47/perilipin 3 contains an a-helix bundle domain with high structural similarity to that of apoE and apoLp-III. Here, we investigated the interaction of apoLp-III from Locusta migratoria with lipid monolayers. Consistent with earlier work we find that insertion of apoLp-III into fluid lipid monolayers is highest for diacylglycerol. We observe a preference for saturated and more highly ordered lipids, suggesting a new mode of interaction for amphipathic a-helix bundles. X-ray reflectivity shows that apoLp-III unfolds at a hydrophobic interface and flexible loops connecting the amphipathic cc-helices stay in solution. X-ray diffraction indicates that apoLp-III insertion into diacylglycerol monolayers induces additional ordering of saturated acyl-chains. These results thus shed important new insight into the protein-lipid interactions of a model exchangeable apolipoprotein with significant implications for its mammalian counterparts. (C) 2013 Elsevier B.V. All rights reserved.

  10. Genome-Wide Association Study of Lp-PLA2 Activity and Mass in the Framingham Heart Study

    Science.gov (United States)

    Suchindran, Sunil; Rivedal, David; Guyton, John R.; Milledge, Tom; Gao, Xiaoyi; Benjamin, Ashlee; Rowell, Jennifer; Ginsburg, Geoffrey S.; McCarthy, Jeanette J.

    2010-01-01

    Lipoprotein-associated phospholipase A2 (Lp-PLA2) is an emerging risk factor and therapeutic target for cardiovascular disease. The activity and mass of this enzyme are heritable traits, but major genetic determinants have not been explored in a systematic, genome-wide fashion. We carried out a genome-wide association study of Lp-PLA2 activity and mass in 6,668 Caucasian subjects from the population-based Framingham Heart Study. Clinical data and genotypes from the Affymetrix 550K SNP array were obtained from the open-access Framingham SHARe project. Each polymorphism that passed quality control was tested for associations with Lp-PLA2 activity and mass using linear mixed models implemented in the R statistical package, accounting for familial correlations, and controlling for age, sex, smoking, lipid-lowering-medication use, and cohort. For Lp-PLA2 activity, polymorphisms at four independent loci reached genome-wide significance, including the APOE/APOC1 region on chromosome 19 (p = 6×10−24); CELSR2/PSRC1 on chromosome 1 (p = 3×10−15); SCARB1 on chromosome 12 (p = 1×10−8) and ZNF259/BUD13 in the APOA5/APOA1 gene region on chromosome 11 (p = 4×10−8). All of these remained significant after accounting for associations with LDL cholesterol, HDL cholesterol, or triglycerides. For Lp-PLA2 mass, 12 SNPs achieved genome-wide significance, all clustering in a region on chromosome 6p12.3 near the PLA2G7 gene. Our analyses demonstrate that genetic polymorphisms may contribute to inter-individual variation in Lp-PLA2 activity and mass. PMID:20442857

  11. U.S. Global Defense Posture, 1783-2011

    Science.gov (United States)

    2012-01-01

    Panama triangle . See Morton, 1959, pp. 247–248. 42 U.S. Global Defense Posture, 1783–2011 that the United States needed to significantly expand its...return for 50 outdated destroyers. Additionally, the British granted the United States leases to air and naval bases in Newfoundland and Bermuda , but...operational needs had largely already been met through an earlier secret deal that gave American ships limited use of British bases on Bermuda , St

  12. Defense Logistics: Marine Corps and Army Reset Liability Estimates

    Science.gov (United States)

    2015-06-22

    reset the item will likely equal the historical average spent to repair the item. 12Unit repair cost refers to the amount of funding to reset a...equipment reset amounting to more than $700 million and that in the event of a crisis the Army would deploy units at a significantly lower readiness level.6...Deputy Assistant Secretary of the Army for Budget. Finally, we interviewed officials from the Office of the Secretary of Defense, Office of Cost

  13. 冠心病伴牙周炎病人血清中Lp-PLA2的研究%Serum Lp-PLA2 levels in periodontitis patients with coronary heart disease

    Institute of Scientific and Technical Information of China (English)

    陈晓霞; 冯伟; 孙钦锋; 刘晓玲

    2011-01-01

    AIM: To explore the relationship between periodontitis and coronary heart disease (CHD)through comparing levels of Lp-PLA2 in serum and the correlation between the level of Lp-PLA2 and periodontal parameters among four groups. METHODS: A total of 120 subjects were included in this clinical study, including 24 CHD patients with moderate to advanced periodontitis (Group C + P) , 36 CHD patients without periodontitis ( Group C), 32 moderate to advanced periodontitis patients without CHD (Group P) and 28 healthy volunteers ( Group H). CHD was diagnosed with diagnostic angiography and periodontitis was diagnosed with clinical examinations. General in-formation and periodontal status of all subjects were recorded and serum samples were collected. The Lp-PLA2 level was determined by ELJSA. RESULTS: One way analysis of variance showed that the serum levels of Lp-PLA2 in patients of group C + P, C and P groups were higher than those of the group H. Pearson correlation analysis showed that serum level of Lp - PLA2 in group P had significantly positive correlation with pocket depth and attachment loss (P<0.05). CONCLUSION; Inflammation of periodontal tissues can increase serum Lp-PLA2 levels, indicating that periodontitis may be a risk factor for coronary heart disease.%目的:通过观察冠心病伴中重度牙周炎、单纯冠心病、单纯中重度牙周炎及健康对照组间血浆中脂蛋白相关磷脂酶A2(lipoprotein-associated phospholipase A2,Lp-PLA2)及其与临床牙周指标的相关性,探讨牙周炎与心血管疾病的相互关系.方法:选取经冠状动脉造影确诊为冠心病且伴有中重度牙周炎的病人24名(C+P组),单纯冠心病病人36名(C组),单纯中重度牙周炎病人32名(P组)及健康对照组(H组)28名.对所有受检者进行口腔检查,记录其基本资料及相关牙周指标,并收集血液标本,采用ELISA检测血浆中Lp-PLA2水平.结果:C+P组、C组、P组的Lp-PLA2水平高于H组,差异有

  14. Study on combat effectiveness of air defense missile weapon system based on queuing theory

    Science.gov (United States)

    Zhao, Z. Q.; Hao, J. X.; Li, L. J.

    2017-01-01

    Queuing Theory is a method to analyze the combat effectiveness of air defense missile weapon system. The model of service probability based on the queuing theory was constructed, and applied to analyzing the combat effectiveness of "Sidewinder" and "Tor-M1" air defense missile weapon system. Finally aimed at different targets densities, the combat effectiveness of different combat units of two types' defense missile weapon system is calculated. This method can be used to analyze the usefulness of air defense missile weapon system.

  15. Convergence in Lp-norm of Fourier Series on the Complete Product of Quaternion Groups with Bounded Orders

    Institute of Scientific and Technical Information of China (English)

    Gyorgy GAT; Rodolfo TOLEDO

    2014-01-01

    A well-known result for Vilenkin systems is the fact that for all 1 < p < ∞ the n-th partial sums of Fourier series of all functions in the space Lp converge to the function in Lp-norm. This statement can not be generalized to any representative product system on the complete product of finite non-abelian groups, but even then it is true for the complete product of quaternion groups with bounded orders and monomial representative product system ordered in a specific way.

  16. LP-925219 maximizes urinary glucose excretion in mice by inhibiting both renal SGLT1 and SGLT2

    OpenAIRE

    Powell, David R.; Smith, Melinda G; Doree, Deon D; Harris, Angela L; Xiong, Wendy W; Mseeh, Faika; Wilson, Alan; Gopinathan, Suma; Diaz, Damaris; Goodwin, Nicole C.; Harrison, Bryce; Strobel, Eric; Rawlins, David B.; Carson, Ken; Zambrowicz, Brian

    2015-01-01

    Sodium-glucose cotransporter 2 (SGLT2) inhibitors are a new class of oral anti-diabetic agents that improve glycemic control by inhibiting SGLT2-mediated renal glucose reabsorption. Currently available agents increase urinary glucose excretion (UGE) to 50% of filtered glucose when SGLT2 is completely inhibited. This led us to test whether LP-925219, a small molecule dual SGLT1/SGLT2 inhibitor, increases UGE to maximal values in wild-type (WT) mice. We first tested LP-925219 inhibition of gluc...

  17. Missile Defense: DOD’s Report Provides Limited Insight on Testing Options for the Ground-based Midcourse Defense System

    Science.gov (United States)

    2014-04-30

    Cochran Ranking Member Subcommittee on Defense Committee on Appropriations United States Senate The Honorable Howard P. " Buck " McKeon Chairman The...System Component Mission Location Ground Based Interceptor (GBI) The interceptor consists of a silo-based, three-stage booster stack and a “hit-to

  18. Dispersion in unit disks

    CERN Document Server

    Dumitrescu, Adrian

    2009-01-01

    We present two new approximation algorithms with (improved) constant ratios for selecting $n$ points in $n$ unit disks such that the minimum pairwise distance among the points is maximized. (I) A very simple $O(n \\log{n})$-time algorithm with ratio 0.5110 for disjoint unit disks. In combination with an algorithm of Cabello \\cite{Ca07}, it yields a $O(n^2)$-time algorithm with ratio of 0.4487 for dispersion in $n$ not necessarily disjoint unit disks. (II) A more sophisticated LP-based algorithm with ratio 0.6495 for disjoint unit disks that uses a linear number of variables and constraints, and runs in polynomial time. The algorithm introduces a novel technique which combines linear programming and projections for approximating distances. The previous best approximation ratio for disjoint unit disks was 1/2. Our results give a partial answer to an open question raised by Cabello \\cite{Ca07}, who asked whether 1/2 could be improved.

  19. Single-nucleotide polymorphisms in LPA explain most of the ancestry-specific variation in Lp(a levels in African Americans.

    Directory of Open Access Journals (Sweden)

    Rahul C Deo

    Full Text Available Lipoprotein(a (Lp(a is an important causal cardiovascular risk factor, with serum Lp(a levels predicting atherosclerotic heart disease and genetic determinants of Lp(a levels showing association with myocardial infarction. Lp(a levels vary widely between populations, with African-derived populations having nearly 2-fold higher Lp(a levels than European Americans. We investigated the genetic basis of this difference in 4464 African Americans from the Jackson Heart Study (JHS using a panel of up to 1447 ancestry informative markers, allowing us to accurately estimate the African ancestry proportion of each individual at each position in the genome. In an unbiased genome-wide admixture scan for frequency-differentiated genetic determinants of Lp(a level, we found a convincing peak (LOD = 13.6 at 6q25.3, which spans the LPA locus. Dense fine-mapping of the LPA locus identified a number of strongly associated, common biallelic SNPs, a subset of which can account for up to 7% of the variation in Lp(a level, as well as >70% of the African-European population differences in Lp(a level. We replicated the association of the most strongly associated SNP, rs9457951 (p = 6 × 10(-22, 27% change in Lp(a per allele, ∼5% of Lp(a variance explained in JHS, in 1,726 African Americans from the Dallas Heart Study and found an even stronger association after adjustment for the kringle(IV repeat copy number. Despite the strong association with Lp(a levels, we find no association of any LPA SNP with incident coronary heart disease in 3,225 African Americans from the Atherosclerosis Risk in Communities Study.

  20. Defense Strategies Against Modern Botnets

    CERN Document Server

    Stankovic, Srdjan

    2009-01-01

    Botnets are networks of compromised computers with malicious code which are remotely controlled and which are used for starting distributed denial of service (DDoS) attacks, sending enormous number of e-mails (SPAM) and other sorts of attacks. Defense against modern Botnets is a real challenge. This paper offers several strategies for defense against Botnets with a list and description of measures and activities which should be carried out in order to establish successful defense. The paper also offers parallel preview of the strategies with their advantages and disadvantages considered in accordance with various criteria.

  1. Quadrennial Defense Review and Ballistic Missile Defense Review

    Science.gov (United States)

    2010-03-11

    global defense posture 3 BMDR Highlights • Outlines a strategy and policy framework to – Defend the homeland against limited ballistic missile attack...abroad – Collaborate closely with allies and partners – Pursue a cooperative and tailored global defense posture – Strengthen US civilian capacity...reviews in 2010 – QDR and BMDR released February 1, 2010 – Nuclear Posture Review to be released this spring – Space Posture Review, with Director of

  2. 2-Summing Operators on $C([0, 1], l_p)$ with Values in $l_1$

    Indian Academy of Sciences (India)

    Dumitru Popa

    2009-04-01

    Let be a compact Hausdorff space, a Banach space, $C(,X)$ the Banach space of continuous -valued functions on under the uniform norm, $U:C(,X)→ Y$ a bounded linear operator and $U^\\#,U_\\#$ two natural operators associated to . For each $1≤ s <∞$, let the conditions $()U\\in _s(C(, X), Y);()U^\\#\\in _s(C(), _s(X, Y));()U_\\#\\in _s(X, _s(C(), Y))$. A general result, [10,13], asserts that () implies () and (). In this paper, in case =2, we give necessary and sufficient conditions that natural operators on $C([0,1],l_p)$ with values in $l_1$ satisfies (), () and (), which show that the above implication is the best possible result.

  3. 倔强的牛犊兰博基尼Huracan LP610-4

    Institute of Scientific and Technical Information of China (English)

    2014-01-01

    作为Gallardo的继任者,兰博基尼全新HuracanLP610-4拥有纯粹而极致的设计、令人惊叹的动力以及绝佳的品质,将超级跑车的驾控体验推向无与伦比的全新巅峰。它性能卓越而又适于日常驾驶,并将各项创新科技完美结合,必将揭开兰博基尼辉煌发展历程的全新篇章。

  4. When LP is the Cure for Your Matching Woes: Approximating Stochastic Matchings

    CERN Document Server

    Bansal, Nikhil; Nagarajan, Viswanath; Rudra, Atri

    2010-01-01

    Consider a random graph model where each possible edge $e$ is present independently with some probability $p_e$. We are just given these numbers $p_e$, and want to build a large/heavy matching in the randomly generated graph. However, the only way we can find out whether an edge is present or not is to query it--and if the edge is indeed present in the graph, we are forced to add it to our matching. Further, each vertex $i$ is allowed to be queried at most $t_i$ times. How should we adaptively query the edges to maximize the expected weight of the matching? We consider several matching problems in this general framework (some of which arise in kidney exchanges and online dating, and others arise in modeling online advertisements); we give LP-rounding based constant-factor approximation algorithms for these problems.

  5. ASYMPTOTICALLY ISOMETRIC COPIES OF lp (1≤p<∞) AND c0 IN BANACH SPACES

    Institute of Scientific and Technical Information of China (English)

    Chen Dongyang

    2006-01-01

    Let X be a Banach space. If there exists a quotient space of X which is asymptotically isometric to l1, then X contains complemented asymptotically isometric copies of l1. Every infinite dimensional closed subspace of l1 contains a complemented subspace of l1 which is asymptotically isometric to l1. Let X be a separable Banach space such that X* contains asymptotically isometric copies of lp (1 < p <∞). Then there exists a quotient space of X which is asymptotically isometric to lq (1/p+1/q=1). Complementedasymptotically isometric copies of c0 in K(X, Y) and W(X, Y) are discussed. Let X be a Gelfand-Phillips space. If X contains asymptotically isometric copies of c0, it has to contain complemented asymptotically isometric copies of c0.

  6. 有形无极 兰博基尼Murcielago LP 607-4 SV

    Institute of Scientific and Technical Information of China (English)

    王岩

    2010-01-01

    用单纯的超跑来形容兰博基尼Murcielago LP 670—4 SV恐怕已不确切,它更应该算辆赛车,拥有它的人应该有着气吞山河的霸气,不单单只是出于对速度的狂热,斗牛士的优雅已经不足以驯服它,要拿出骑牛的牛仔精神或许才能与其僵持。我没想到与它的第一次相遇竟会在F1赛道上,坐骑的不同清楚地告诉我——今天不是来享受这里,而是来征服这里。

  7. 暴力学的化身LAMBORGHINIAVENTADOR LP 700-4

    Institute of Scientific and Technical Information of China (English)

    包崇美

    2011-01-01

    对速度的痴狂让兰博基尼总是出人意料地推出一款又一款令人咋舌的超级跑车。继3月份日内瓦车展首发之后.兰博基尼Murcielago的换代车型——Aventador LP700—4于上海车展首发亮相.并将很快引入国内销售。锋利的多面几何形车身让其显得粗犷而霸气.700马力(515kW)的最大功率又让其充满了如“蛮牛”般的力量。不得不说.它是暴力美学的化身。

  8. Super-Brownian motion: Lp-convergence of martingales through the pathwise spine decomposition

    CERN Document Server

    Murillo-Salas, A E Kyprianou A

    2011-01-01

    Evans (1992) described the semi-group of a superprocess with quadratic branching mechanism under a martingale change of measure in terms of the semi-group of an immortal particle and the semigroup of the superprocess prior to the change of measure. This result, commonly referred to as the spine decomposition, alludes to a pathwise decomposition in which independent copies of the original process `immigrate' along the path of the immortal particle. For branching particle diffusions the analogue of this decomposition has already been demonstrated in the pathwise sense, see for example Hardy and Harris (2009). The purpose of this short note is to exemplify a new {\\it pathwise} spine decomposition for supercritical super-Brownian motion with general branching mechanism (cf. Kyprianou et al. (2010)) by studying $L^p$ convergence of naturally underlying additive martingales in the spirit of analogous arguments for branching particle diffusions due to Hardys and Harris (2009). Amongst other ingredients, the Dynkin-K...

  9. Molecular strategies of plant defense and insect counter-defense

    Institute of Scientific and Technical Information of China (English)

    KEYANZHU-SALZMAN; JIAN-LONGBI; TONG-XIANLIU

    2005-01-01

    The prediction of human population growth worldwide indicates there will be a need to substantially increase food production in order to meet the demand on food supply.This can be achieved in part by the effective management of insect pests. Since plants have co-evolved with herbivorous insects for millions of years, they have developed an array of defense genes to protect themselves against a wide variety of chewing and sucking insects.Using these naturally-occurring genes via genetic engineering represents an environmentally friendly insect pest-control measure. Insects, however, have been actively evolving adaptive mechanisms to evade natural plant defenses. Such evolved adaptability undoubtedly has helped insects during the last century to rapidly overcome a great many humanimposed management practices and agents, including chemical insecticides and genetically engineered plants. Thus, better understanding of the molecular and genetic basis of plant defense and insect counter-defense mechanisms is imperative, not only from a basic science perspective, but also for biotechnology-based pest control practice. In this review, we emphasize the recent advance and understanding of molecular strategies of attack-counterattack and defense-counter-defense between plants and their herbivores.

  10. Effects of Supportive Educational Program on Anxiety of Mothers of Children Undergoing the Lumbar Puncture (LP

    Directory of Open Access Journals (Sweden)

    Mousa Mahdizadeh

    2016-07-01

    Full Text Available Background: Lumbar Puncture test is one of the most stressful diagnostic procedures in pediatric ward that its prescription put mothers under extreme pressure. There are limited interventions in this regard. Aim: determining the impact of supportive educational program on the anxiety of mothers whose children are undergoing lumbar puncture (LP. Method: the present study is a randomized controlled clinical trial carried out in 2015. Sixty mothers of children undergoing lumbar puncture and hospitalized 3educational hospitals of Mashhad, Iran, were randomly divided to control group (n=30 and intervention group (n=30. The intervention group received supportive program during a session of 60 min. Spielberger State-Trait Anxiety Inventory (STAI was selected as the research tool. Finally, data were analyzed by Chi-square test, independent t-test using SPSS v.16 software. Results: The mean age of the mothers was 27.3±5.3 and 26.0±3.1, respectively. The mean pre-interventions maternal manifest anxiety was 51.9±6.2 and 53.4±4.3 out of 80, respectively, in the intervention and control groups. The mean post-interventions maternal manifest anxiety was 44.9±5.1 and 52.7±4.2, respectively, in the intervention and control groups. According to the results of independent t-test, significant difference was observed statistically for the mean maternal manifest anxiety between the two groups (p> 0.001. Implications for Practice: Regarding the reduction of maternal anxiety in the intervention group, which is possible because of the attention to the emotional needs of mothers, in addition to proper training; this program can be considered as an effective method to reduce maternal anxiety before the LP test.

  11. Quadrennial Defense Review 2014

    Science.gov (United States)

    2014-01-01

    periphery will continue to pose a security challenge. The United States is willing to undertake security cooperation with Russia , both in the... Russia to increase transparency and reduce the risk of military miscalculation. In the Western Hemisphere, predominant security challenges no longer...three-dimensional printers could revolutionize manufacturing and logistics related to warfare. New ways of developing WMD – such as biotechnology

  12. A Defensive Battle

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    China jumps into action to counteract the fallout from the crippling U.S. financial crisis The hard-won passage of the unprec-edented $700-billion bank bailout plan in the United States has finally brought hope of an end to the coun

  13. 77 FR 5613 - C3 Capital Partners II, L.P.; Notice Seeking Exemption Under 312 of the Small Business Investment...

    Science.gov (United States)

    2012-02-03

    ... ADMINISTRATION C3 Capital Partners II, L.P.; Notice Seeking Exemption Under 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that C3 Capital Partners II, L.P., 4520 Main Street, Suite 1600, Kansas City, Missouri 64111-7700, a Federal Licensee under the Small Business Investment...

  14. 76 FR 17180 - C3 Capital Partners II, L.P.; Notice Seeking Exemption Under 312 of the Small Business Investment...

    Science.gov (United States)

    2011-03-28

    ... ADMINISTRATION C3 Capital Partners II, L.P.; Notice Seeking Exemption Under 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that C3 Capital Partners IT, L.P., 4520 Main Street, Suite 1600, Kansas City, Missouri, 64111-7700, a Federal Licensee under the Small Business...

  15. 77 FR 76586 - GC SBIC IV, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act...

    Science.gov (United States)

    2012-12-28

    ... Regulations (13 CFR 107.730). GC SBIC IV, L.P. provided loan financing to Massage Envy LLC, 14350 N. 87th... the Regulations because Massage Envy LLC used financing proceeds from GC SBIC IV, L.P. in part...

  16. 77 FR 74544 - Eagle Fund III, L.P., License No. 07/07-0116; Notice Seeking Exemption Under Section 312 of the...

    Science.gov (United States)

    2012-12-14

    ... ADMINISTRATION Eagle Fund III, L.P., License No. 07/07-0116; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Eagle Fund III, L.P... interest, of the Small Business Administration Rules and Regulations (13 CFR part 107). Eagle Fund III,...

  17. 77 FR 74545 - Eagle Fund III-A, L.P.; License No. 07/07-0117: Notice Seeking Exemption Under Section 312 of the...

    Science.gov (United States)

    2012-12-14

    ... ADMINISTRATION Eagle Fund III-A, L.P.; License No. 07/07-0117: Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Eagle Fund III-A, L.P... interest, of the Small Business Administration Rules and Regulations (13 CFR part 107). Eagle Fund III-...

  18. Defense Meteorological Satellite Program (DMSP)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Defense Meteorological Satellite Program (DMSP) satellites collect visible and infrared cloud imagery as well as monitoring the atmospheric, oceanographic,...

  19. 77 FR 34034 - Corpus Christi Liquefaction, LLC; Cheniere Corpus Christi Pipeline, L.P.; Notice of Intent To...

    Science.gov (United States)

    2012-06-08

    ... Energy Regulatory Commission Corpus Christi Liquefaction, LLC; Cheniere Corpus Christi Pipeline, L.P.; Notice of Intent To Prepare an Environmental Assessment for the Planned Corpus Christi LNG Terminal and... assessment (EA) that will discuss the environmental impacts of the planned Corpus Christi LNG Terminal...

  20. 77 FR 58118 - Freeport LNG Development, L.P., FLNG Liquefaction, LLC, FLNG Liquefaction 2, LLC, FLNG...

    Science.gov (United States)

    2012-09-19

    ... Energy Regulatory Commission Freeport LNG Development, L.P., FLNG Liquefaction, LLC, FLNG Liquefaction 2, LLC, FLNG Liquefaction 3, LLC; Notice of Application Take notice that on August 31, 2012, Freeport LNG... natural gas liquefaction and export facilities will be constructed adjacent to the existing Freeport...

  1. 77 FR 33446 - Jordan Cove Energy Project, L.P.; Application for Long-Term Authorization to Export Liquefied...

    Science.gov (United States)

    2012-06-06

    ... Cove Energy Project, L.P.; Application for Long-Term Authorization to Export Liquefied Natural Gas Produced From Domestic and Canadian Natural Gas Resources to Non-Free Trade Agreement Countries for a 25..., multi-contract authorization to export as liquefied natural gas (LNG) both natural gas...

  2. [Study on the gas-phase reaction of alpha-pinene with ozone by LP-FTIR].

    Science.gov (United States)

    Liu, Zhao-rong; Hu, Di

    2004-07-01

    The gas-phase reaction of a-pinene with ozone was tailed by LP-FTIR under 1.0 x 10(5) Pa and (296 +/- 3)K. The spectra were analyzed and a preliminary predication of the possible products was made. Then the mechanism of this reaction was extrapolated according to the IR data.

  3. Simultaneous measurement of curvature and temperature based on LP 11 mode Bragg grating in seven-core fiber

    Science.gov (United States)

    Zhang, Yunshan; Zhang, Weigang; Zhang, Yanxin; Wang, Song; Yu, Lin; Yan, Yieyi

    2017-05-01

    A robust and compact fiber sensor for simultaneous measurement of curvature and temperature based on LP 11 mode Bragg grating is proposed and demonstrated in this paper. The sensor is formed by splicing a short piece of seven-core fiber (SCF) with Bragg grating to single mode fiber (SMF). The Bragg grating is inscribed by UV light exposure, and mainly LP 01 resonance peak and LP 11 resonance peak are observed in the reflection spectrum. The experimental results show that the wavelength of the LP 11 Bragg resonance is insensitive to curvature but the power is very sensitive to curvature. The curvature sensitivity is  -7.27 dB/m-1 with a linearity of 0.997 in the curvature range of 0-1 m-1. The temperature characteristic shows that the Bragg resonance has almost the same sensitivity as the common fiber Bragg grating (FBG). The sensor is also available to be independent of the ambient refractive index(RI).

  4. 76 FR 55909 - CITGO Refining and Chemicals Company L.P. v. Port of Corpus Christi Authority of Nueces County...

    Science.gov (United States)

    2011-09-09

    ... From the Federal Register Online via the Government Publishing Office FEDERAL MARITIME COMMISSION CITGO Refining and Chemicals Company L.P. v. Port of Corpus Christi Authority of Nueces County, Texas... ``Complainant,'' against the Port of Corpus Christi Authority of Nueces County, Texas (PCCA)...

  5. G 207-9 and LP 133-144: light curve analysis and asteroseismology of two ZZ Ceti stars

    CERN Document Server

    Bognár, Zs; Molnár, L; Pápics, P I; Plachy, E; Verebélyi, E; Sódor, Á

    2016-01-01

    G 207-9 and LP 133-144 are two rarely observed ZZ Ceti stars located in the middle and close to the blue edge of the ZZ Ceti instability domain, respectively. We aimed to observe them at least during one observing season at Konkoly Observatory with the purpose of extending the list of known pulsation modes for asteroseismic investigations and detect any significant changes in their pulsational behaviour. We determined five and three new normal modes of G 207-9 and LP 133-144, respectively. In LP 133-144, our frequency analysis also revealed that at least at three modes there are actually triplets with frequency separations of ~4 microHz. The rotational period of LP 133-144 based on the triplets is ~42 h. The preliminary asteroseismic fits of G 207-9 predict Teff=12 000 or 12 400 K and M*=0.855-0.870 MSun values for the effective temperature and mass of the star, depending on the assumptions on the spherical degree (l) values of the modes. These results are in agreement with the spectroscopic determinations. I...

  6. 76 FR 4097 - Erie Boulevard Hydropower, L.P.; Notice of Application Tendered for Filing With the Commission...

    Science.gov (United States)

    2011-01-24

    ... License. b. Project No.: 2713-082. c. Date Filed: December 30, 2010. d. Applicant: Erie Boulevard... Contact: Jon Elmer, Erie Boulevard Hydropower, L.P, 800 Starbuck Ave., Suite 802, Watertown, New York... generation, while the Heuvelton and Eel Weir developments typically operate in a run-of-river mode. With...

  7. 77 FR 45596 - Shell Energy North America (US), L.P. v. California Independent System Operator Corporation...

    Science.gov (United States)

    2012-08-01

    ... Doc No: 2012-18774] DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EL12-88 -000] Shell Energy North America (US), L.P. v. California Independent System Operator Corporation; Notice of Complaint Take notice that on July 25, 2012, pursuant to Rule 206 of the Federal Energy...

  8. 75 FR 76037 - HAVI Logistics, North America a Subsidiary of HAVI Group, LP Including On-Site Leased Workers of...

    Science.gov (United States)

    2010-12-07

    ... Employment and Training Administration HAVI Logistics, North America a Subsidiary of HAVI Group, LP Including... Logistics, North America, Lisle, IL; Amended Certification Regarding Eligibility To Apply for Worker... Assistance on September 3, 2010, applicable to workers of HAVI Logistics, North America, a subsidiary of HAVI...

  9. 78 FR 1851 - Sabine Pass Liquefaction, LLC and Sabine Pass LNG, L.P.; Notice of Intent To Prepare an...

    Science.gov (United States)

    2013-01-09

    ... Energy Regulatory Commission Sabine Pass Liquefaction, LLC and Sabine Pass LNG, L.P.; Notice of Intent To Prepare an Environmental Assessment for the Proposed Sabine Pass Liquefaction Modification Project and... impacts of the Sabine Pass Liquefaction Modification Project (Project) involving the modification...

  10. 75 FR 68347 - Sabine Pass Liquefaction LLC, and Sabine Pass LNG, L.P.; Notice of Intent To Prepare an...

    Science.gov (United States)

    2010-11-05

    ... Energy Regulatory Commission Sabine Pass Liquefaction LLC, and Sabine Pass LNG, L.P.; Notice of Intent To Prepare an Environmental Assessment for the Planned Sabine Pass Liquefaction Project and Request for... impacts of the Sabine Pass Liquefaction Project (Project) involving construction and operation...

  11. 75 FR 49926 - Arena Energy, L.P. v. Sea Robin Pipeline Company, LLC; Notice of Complaint

    Science.gov (United States)

    2010-08-16

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Arena Energy, L.P. v. Sea Robin Pipeline Company, LLC; Notice of Complaint.... (Complainant) filed a formal complaint against Sea Robin Pipeline Company, LLC (Respondent) alleging that...

  12. 76 FR 59682 - Erie Boulevard Hydropower L.P.; Notice of Dispute Resolution Panel Meeting and Technical Conference

    Science.gov (United States)

    2011-09-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Erie Boulevard Hydropower L.P.; Notice of Dispute Resolution Panel Meeting and Technical Conference On September 16, 2011, Commission staff, in response to the filing of notice...

  13. 75 FR 71122 - Erie Boulevard Hydropower L.P.; Notice of Scoping Meetings and Environmental Site Review

    Science.gov (United States)

    2010-11-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Erie Boulevard Hydropower L.P.; Notice of Scoping Meetings and Environmental Site Review November 15, 2010. Commission staff will be conducting two public scoping meetings and an...

  14. Relationship of plasma levels of LP-PLA2, GMP, LPA and platelet activation markers with transient ischemic attack

    Institute of Scientific and Technical Information of China (English)

    Hang Li

    2015-01-01

    Objective:To explore the relationship of plasma levels of LP-PLA2, GMP, LPA and platelet activation markers with transient ischemic attack(TIA).Methods:A total of 87 cases with TIA were collected, and all patients were treated with ozagrel (120mg/times/day for 2 weeks). Fasting blood were collected in 24 h after attack and 7d, 14 days after treatment respectively, then flow cytometry was used to detect indicators of platelet activation, such as CD63, PAC-1, GPⅡb /Ⅲa, and the plasma levels of LP-PLA2, GMP, LPA. The dynamic changes of the such indexes and the differences between different populations were analyzed.Results:The plasma levels of LP-PLA2, GMP, LPA and the platelet activation indexes including CD63, PAC-1, GPⅡb/Ⅲa of patients with TIA were all significantly higher than control group (allP<0.05). One day after treatment of sodium Ozagrel, the plasma levels of LP-PLA2, GMP, LPA and the platelet activation indexes such as CD63, PAC-1, GPⅡb/Ⅲa of patients with TIA began to decline, and returned to normal in the treatment of 7 d or 14 d.Conclusions:Platelet activation plays an important role in the occurrence of TIA, and antiplatelet therapy can effectively inhibit platelet activation, which has positive significance in the treatment of TIA.

  15. 75 FR 8921 - Grant of Authority for Subzone Status; Brightpoint North America L.P. (Cell Phone Kitting and...

    Science.gov (United States)

    2010-02-26

    ... Phone Kitting and Distribution) Indianapolis, IN Pursuant to its authority under the Foreign-Trade Zones... authority to establish a special-purpose subzone at the cell phone kitting and distribution facilities of... kitting and distribution of cell phones at the facilities of Brightpoint North America L.P., located...

  16. 77 FR 70429 - Gulf South Pipeline Company, LP; Notice of Intent To Prepare an Environmental Assessment for the...

    Science.gov (United States)

    2012-11-26

    ... operation of facilities by Gulf South Pipeline Company, LP (Gulf South) in Jasper, Forrest, Perry, Greene... its decision-making process to determine whether the project is in the public convenience and... an easement to construct, operate, and maintain the planned facilities. The company would seek...

  17. 76 FR 9808 - U.S. Customs and Border Protection Accreditation and Approval of Saybolt LP, as a Commercial...

    Science.gov (United States)

    2011-02-22

    ... SECURITY U.S. Customs and Border Protection Accreditation and Approval of Saybolt LP, as a Commercial Gauger and Laboratory AGENCY: U.S. Customs and Border Protection, Department of Homeland Security. ACTION... Services, U.S. Customs and Border Protection, 1300 Pennsylvania Avenue, NW., Suite 1500N, Washington,...

  18. Defense Spending and the Economy

    Science.gov (United States)

    1983-12-07

    the first resolution. Our forecast projects continued growth in the economy and moderate inflation for one or possibly two years, despite federal...than provided in the resolution. Additional emphasis on defense would, of course, promote defense-intensive sectors of the economy at the expense of...others, but CBO believes the economy could accommodate such shifts without significant adverse effects on macroeconomic variables such as employment

  19. Theater Missile Defense Integration Issues

    Science.gov (United States)

    1993-06-01

    high endoatmospheric defense interceptor (HEDI) proposed t earlier. EADTB. Extended Air Defense Test Bed. A computer-based analysis center for...for attacking deeper elements of an aggressors’s ground forces. Known in NATO as Follow-on Force Attack ( FOFA ). JSTARS. Joint surveillance target...AFIA/INKS ATTN. INKS AFIS/INT ATTN: INT AIR hORCE CTR FOR STUDIES & ANALYSIS ATTN: AFSAA/SAKI 9 Dist-1 w^mmmm mmmm^-mmmemH

  20. Ks- and Lp-band polarimetry on stellar and bow-shock sources in the Galactic center

    Science.gov (United States)

    Buchholz, R. M.; Witzel, G.; Schödel, R.; Eckart, A.

    2013-09-01

    Context. Infrared observations of the Galactic center (GC) provide a unique opportunity to study stellar and bow-shock polarization effects in a dusty environment. Aims: The goals of this work are to present new Ks- and Lp-band polarimetry on an unprecedented number of sources in the central parsec of the GC, thereby expanding our previous results in the H- and Ks-bands. Methods: We use AO-assisted Ks- and Lp-band observations, obtained at the ESO VLT. High precision photometry and the new polarimetric calibration method for NACO allow us to map the polarization in a region of 8'' × 25'' (Ks) resp. 26'' × 28'' (Lp). These are the first polarimetric observations of the GC in the Lp-band in 30 years, with vastly improved spatial resolution compared to previous results. This allows resolved polarimetry on bright bow-shock sources in this area for the first time at this wavelength. Results: We find foreground polarization to be largely parallel to the Galactic plane (Ks-band: 6.1% at 20°, Lp-band: 4.5% at 20°), in good agreement with our previous findings and with older results. The previously described Lp-band excess in the foregound polarization towards the GC could be confirmed here for a much larger number of sources. The bow-shock sources contained in the FOV seem to show a different relation between the polarization in the observed wavelength bands than what was determined for the foreground. This points to the different relevant polarization mechanisms. The resolved polarization patterns of IRS 5 and 10W match the findings we presented earlier for IRS 1W. Additionally, intrinsic Lp-band polarization was measured for IRS 1W and 21, as well as for other, less prominent mid-infrared-excess sources (IRS 2S, 2L, 5NE). The new data offer support for the presumed bow-shock nature of several of these sources (1W, 5, 5NE, 10W, 21) and for the model of bow-shock polarization presented in our last work. Tables 1 and 2 are available in electronic form at http

  1. 76 FR 14987 - United States v. Graftech International Ltd. and Seadrift Coke, L.P.; Public Comments and...

    Science.gov (United States)

    2011-03-18

    .... (4) Low-elasticity of demand for the goods, which means that increasing the price for the goods does..., 15 U.S.C. 18. That loss of competition likely would result in higher prices, reduced output and less... graphite electrodes, and concluded that the merger likely would result in higher prices, reduced output...

  2. Anti-SLA/LP alone or in combination with anti-Ro52 and fine specificity of anti-Ro52 antibodies in patients with autoimmune hepatitis.

    Science.gov (United States)

    Zachou, Kalliopi; Gampeta, Stella; Gatselis, Nikolaos K; Oikonomou, Katerina; Goulis, John; Manoussakis, Menelaos N; Renaudineau, Yves; Bogdanos, Dimitrios P; Dalekos, George N

    2015-02-01

    Antibodies (Abs) to soluble liver antigen/liver pancreas (anti-SLA/LP) are considered markers of worse prognosis and outcome in patients with autoimmune hepatitis (AIH) although this assumption has recently been attributed to their frequent co-expression with Abs against Ro52 (anti-Ro52). To assess the clinical significance of anti-SLA/LP Abs alone or in combination with anti-Ro52 in AIH patients and determine the immunodominant Ro52 epitopes according to the anti-SLA/LP status. Twenty-three anti-SLA/LP-positive and 106 anti-SLA/LP-negative AIH patients were included. Anti-SLA/LP were determined by ELISA using recombinant antigen, and confirmed by immunoblot using cytosolic rat liver fraction or HuH-7 extract. Anti-Ro52 Abs were determined by ELISA using recombinant antigen. Epitope mapping was assessed by ELISA using overlapping peptides covering the whole Ro52 protein in 26 AIH patients and 12 patients with Sjögren's syndrome. Anti-SLA/LP positivity was not associated with the clinical, laboratory or histological characteristics of AIH patients. Treatment response, corticosteroid withdrawal, relapse after stopping treatment and outcome, were not associated with the presence of anti-SLA/LP, anti-Ro52 or double reactivity. Moreover, Ro52 epitope mapping revealed new epitopes unique for AIH and independent from anti-SLA/LP positivity. Neither anti-SLA/LP nor anti-Ro52 Abs or their combination could specify a distinct group of AIH patients in terms of clinical characteristics, treatment response and outcome. Further studies are needed to clarify whether the newly discovered immunodominant epitopes of Ro52 antigen which were associated specifically with AIH have any clinical or pathogenetic significance in AIH. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  3. Foreign Internal Defense

    Science.gov (United States)

    2010-07-12

    basis for today’s FID doctrine. d. In recent times, the United States has provided the same type of NA in El Salvador, Colombia , Kuwait, the...transfers and related services have reached enormous dimensions and involve most of the world’s nations, either as a seller /provider or buyer...measures and consideration of the following: (1) Street or organized crime. (2) Foreign intelligence services. (3) Local populace animosity

  4. 22 CFR 46.3 - Aliens whose departure is deemed prejudicial to the interests of the United States.

    Science.gov (United States)

    2010-04-01

    ... country cooperating with the United States in measures adopted to promote the peace, defense, or safety of the United States or such other country. (d) Any alien who seeks to depart from the United States for... United States or the United Nations for the defense of any other country. (c) Any alien who seeks...

  5. 76 FR 72391 - Defense Logistics Agency Revised Regulation 1000.22, Environmental Considerations in Defense...

    Science.gov (United States)

    2011-11-23

    ... Logistics Agency Revised Regulation 1000.22, Environmental Considerations in Defense Logistics Agency Actions AGENCY: Defense Logistics Agency, Department of Defense. ACTION: Revised Defense Logistics Agency Regulation (DLAR) 1000.22. SUMMARY: On May 18, 2011, the Defense Logistics Agency (DLA) published a Notice of...

  6. 76 FR 53119 - Defense Logistics Agency Revised Regulation 1000.22, Environmental Considerations in Defense...

    Science.gov (United States)

    2011-08-25

    ... Office of the Secretary Defense Logistics Agency Revised Regulation 1000.22, Environmental Considerations in Defense Logistics Agency Actions AGENCY: Defense Logistics Agency, Department of Defense. ACTION: Comment Addressed on Notice of Availability (NOA) of Revised Defense Logistics Agency Regulation (DLAR...

  7. Defensive medicine among neurosurgeons in the Netherlands: a national survey.

    Science.gov (United States)

    Yan, Sandra C; Hulsbergen, Alexander F C; Muskens, Ivo S; van Dam, Marjel; Gormley, William B; Broekman, Marike L D; Smith, Timothy R

    2017-09-20

    In defensive medicine, practice is motivated by legal rather than medical reasons. Previous studies have analyzed the correlation between perceived medico-legal risk and defensive behavior among neurosurgeons in the United States, Canada, and South Africa, but not yet in Europe. The aim of this study is to explore perceived liability burdens and self-reported defensive behaviors among neurosurgeons in the Netherlands and compare their practices with their non-European counterparts. A survey was sent to 136 neurosurgeons. The survey included questions from several domains: surgeon characteristics, patient demographics, type of practice, surgeon liability profile, policy coverage, defensive practices, and perception of the liability environment. Survey responses were analyzed and summarized. Forty-five neurosurgeons filled out the questionnaire (response rate of 33.1%). Almost half (n = 20) reported paying less than 5% of their income to annual malpractice premiums. Nearly all respondents view their insurance premiums as a minor or no burden (n = 42) and are confident that in their coverage is sufficient (n = 41). Most neurosurgeons (n = 38) do not see patients as "potential lawsuits". Relative to their American peers, Dutch neurosurgeons view their insurance premiums as less burdensome, their patients as a smaller legal threat, and their practice as less risky in general. They are sued less often and engage in fewer defensive behaviors than their non-European counterparts. The medico-legal climate in the Netherlands may contribute to this difference.

  8. Latvian Security and Defense Policy within the Twenty-First Century Security Environment

    Directory of Open Access Journals (Sweden)

    Rublovskis Raimonds

    2014-12-01

    Full Text Available The aim of this paper is to analyze fundamental factors which form and profoundly shape security and defense policy of the Republic of Latvia. One can argue that historical background, geographical location, common institutional history within the former Soviet Union, the Russia factor, the relative smallness of the territory of state and the population, the ethnic composition of the population, the low density of the population and rather limited financial and manpower resources available for the defense of the Republic of Latvia are the key factors of influence on the state security and defense policy. The core principles of the security and defense policy of Latvia are the membership in powerful global military alliance of NATO and bilateral strategic partnership with the United States. However, security and defense cooperation among the three Baltic States as well as enhanced cooperation within the Baltic-Nordic framework is seen as an important supplementary factor for the increased security of the Republic of Latvia. Latvia has developed a sustainable legal and institutional framework in order to contribute to state security and defense; however, security challenges and significant changes within the global security environment of the twenty-first century will further challenge the ability of the Republic of Latvia to sustain its current legal framework, and more importantly, current institutional structure of Latvian security and defense architecture. Significant internal and external challenges will impact the fundamental pillars of Latvian security and defense policy, such as American strategic shift to the Pacific, and lack of political will to increase defense budgets in European part of NATO. It has to be clear that very independence, security and defense of the Republic of Latvia depend on the ability of NATO to remain an effective organization with timely and efficient decision-making, and the ability of the United States to remain

  9. The electron and the ion density characteristic near the F ring by Cassini/RPWS/LP

    Science.gov (United States)

    Morooka, Michiko; Wahlund, Jan-Erik; Andrews, David; Ye, Sheng-Yi; Kurth, William

    2017-04-01

    Cassini observations revealed that there are a large amount of nm and μm sized dust grains and their electrical interaction with the surrounding plasma near the moon Enceladus and the E ring. In this region, the small grains are negatively charged by attaching the electrons, resulting the unbalance in the ion and the electron densities (the ion density higher than the electron density). Similar type observations are expected near the faint F and G ring that are composed of small grains. During the grand finale, from December 2016, Cassini has been orbiting Saturn with closest approach just outside the F ring. We will show the electron and ion densities of those orbits obtained by the Langmuir probe onboard Cassini (RPWS/LP). Preliminary results showed: 1) both the electron and the ion density enhancement occurred near the equator (Z = ±0.5RS). 2) The electron densities at the equator are about the order of 1 cm-3 (varies from 2 to 8), while the ion densities are an order of magnitude larger than the electrons up to 300 cm-3. 3) The electron density depletion has been observed centered at the equator around ±0.05 RS in Z. Coincide this region, the LP sweep current noise due to the dust grain's hitting the probe were observed. On the other hand, the peak of the electron density seems to be located slightly northward above the equator at ˜0.05 RS. 4) One of the events showed a local electron density enhancement near the L-shell at L = 3. The obtained characteristics are similar to what have been found in the E ring near the Enceladus orbit. In the E ring, the electron density enhancement region was centered at the equator in Z ±˜0.5RS, the electron bite out occurred at Z = ±0.045RS, and the electron density peaks were somewhat higher in the northern hemisphere. A possible explanation for the location differences in the charged dust density peak and the plasma density peak can be due to that the magnetic equator is located slightly north (+0.04RS) of the equator

  10. Beryllium--important for national defense

    Science.gov (United States)

    Boland, M.A.

    2012-01-01

    Beryllium is one of the lightest and stiffest metals, but there was little industrial demand for it until the 1930s and 1940s when the aerospace, defense, and nuclear sectors began using beryllium and its compounds. Beryllium is now classified by the U.S. Department of Defense as a strategic and critical material because it is used in products that are vital to national security. The oxide form of beryllium was identified in 1797, and scientists first isolated metallic beryllium in 1828. The United States is the world's leading source of beryllium. A single mine at Spor Mountain, Utah, produced more than 85 percent of the beryllium mined worldwide in 2010. China produced most of the remainder, and less than 2 percent came from Mozambique and other countries. National stockpiles also provide significant amounts of beryllium for processing. To help predict where future beryllium supplies might be located, U.S.Geological Survey (USGS) scientists study how and where beryllium resources are concentrated in Earth's crust and use that knowledge to assess the likelihood that undiscovered beryllium resources may exist. Techniques to assess mineral resources have been developed by the USGS to support the stewardship of Federal lands and to better evaluate mineral resource availability in a global context. The USGS also compiles statistics and information on the worldwide supply of, demand for, and flow of beryllium. These data are used to inform U.S. national policymaking.

  11. Truncated Form of the Epstein-Barr Virus Protein EBNA-LP Protects against Caspase-Dependent Apoptosis by Inhibiting Protein Phosphatase 2A▿

    Science.gov (United States)

    Garibal, Julie; Hollville, Émilie; Bell, Andrew I.; Kelly, Gemma L.; Renouf, Benjamin; Kawaguchi, Yasushi; Rickinson, Alan B.; Wiels, Joëlle

    2007-01-01

    The Epstein-Barr virus (EBV)-encoded leader protein, EBNA-LP, strongly activates the EBNA2-mediated transcriptional activation of cellular and viral genes and is therefore important for EBV-induced B-cell transformation. However, a truncated form of EBNA-LP is produced in cells infected with variant EBV strains lacking EBNA2 due to a genetic deletion. The function of this truncated form is unknown. We show here that some Burkitt's lymphoma cells harboring defective EBV strains are specifically resistant to the caspase-dependent apoptosis induced by verotoxin 1 (VT-1) or staurosporine. These cells produced low-molecular-weight Y1Y2-truncated isoforms of EBNA-LP, which were partly localized in the cytoplasm. The transfection of sensitive cells with constructs encoding truncated EBNA-LP isoforms, but not full-length EBNA-LP, induced resistance to caspase-mediated apoptosis. Furthermore, VT-1 induced protein phosphatase 2A (PP2A) activation in sensitive cells but not in resistant cells, in which the truncated EBNA-LP interacted with this protein. Thus, the resistance to apoptosis observed in cells harboring defective EBV strains most probably results from the inactivation of PP2A via interactions with low-molecular-weight Y1Y2-truncated EBNA-LP isoforms. PMID:17494066

  12. 高密度电阻率法探测地下人防巷道装置类型选择与异常识别%unit type ChoSen for hiGh denSity reSiStivity method uSed in deteCtion of underGround Civil Air defenSe workS And reCoGnition of AnomAly

    Institute of Scientific and Technical Information of China (English)

    郭厚军; 张国鸿

    2015-01-01

    Based on Wenner arrangement and tri-pole unit test over known underground civil air defense works, and analysis of anomalous features, this paper introduced the use of right unit type of high density resistivity method that tells difference in resistivity of underground media and how to recognize the anomalous marker correctly.%通过在已知在已揭露的地下人防巷道上方高密度电阻率法中温纳装置、三极装置的试验以及异常特征分析,说明利用地下介质的电阻率差异,采用高密度电阻率法探测地下人防巷道工作时,应选择好装置类型,且要正确地识别其异常标志。

  13. Variation in LPA is associated with Lp(a levels in three populations from the Third National Health and Nutrition Examination Survey.

    Directory of Open Access Journals (Sweden)

    Logan Dumitrescu

    Full Text Available The distribution of lipoprotein(a [Lp(a] levels can differ dramatically across diverse racial/ethnic populations. The extent to which genetic variation in LPA can explain these differences is not fully understood. To explore this, 19 LPA tagSNPs were genotyped in 7,159 participants from the Third National Health and Nutrition Examination Survey (NHANES III. NHANES III is a diverse population-based survey with DNA samples linked to hundreds of quantitative traits, including serum Lp(a. Tests of association between LPA variants and transformed Lp(a levels were performed across the three different NHANES subpopulations (non-Hispanic whites, non-Hispanic blacks, and Mexican Americans. At a significance threshold of p<0.0001, 15 of the 19 SNPs tested were strongly associated with Lp(a levels in at least one subpopulation, six in at least two subpopulations, and none in all three subpopulations. In non-Hispanic whites, three variants were associated with Lp(a levels, including previously known rs6919246 (p = 1.18 × 10(-30. Additionally, 12 and 6 variants had significant associations in non-Hispanic blacks and Mexican Americans, respectively. The additive effects of these associated alleles explained up to 11% of the variance observed for Lp(a levels in the different racial/ethnic populations. The findings reported here replicate previous candidate gene and genome-wide association studies for Lp(a levels in European-descent populations and extend these findings to other populations. While we demonstrate that LPA is an important contributor to Lp(a levels regardless of race/ethnicity, the lack of generalization of associations across all subpopulations suggests that specific LPA variants may be contributing to the observed Lp(a between-population variance.

  14. Low frequency of anti-SLA/LP autoantibody in Japanese adult patients with autoimmune liver diseases: analysis with recombinant antigen assay.

    Science.gov (United States)

    Miyakawa, Hiroshi; Kawashima, Yumi; Kitazawa, Eriko; Kawaguchi, Naomi; Kato, Takashi; Kikuchi, Kentaro; Imai, Erika; Fujikawa, Hirotoshi; Hashimoto, Etsuko; Schlumberger, Wolfgang

    2003-08-01

    Anti-soluble liver antigen/liver pancreas (SLA/LP) autoantibody has been proposed to be one of the autoantibodies characterizing autoimmune hepatitis (AIH). Recently, one of the autoantigens to anti-SLA/LP was identified as a UGA suppressor tRNA-associated protein. Although the function of this protein remains unknown, the recombinant protein has been prokaryotically expressed. Using this protein as an antigen, a recombinant immunoassay for anti-SLA/LP autoantibody has been established and the frequency and significance of this autoantibody have been discussed in European countries. So, in the present study, we investigated anti-SLA/LP autoantibodies in Japanese patients with autoimmune liver diseases using the recombinant antigen ELISA and Western blot assay. Seventy-five patients with AIH type 1, 5 with AIH type 2, 46 with primary biliary cirrhosis, 10 with primary sclerosing cholangitis, 47 with chronic hepatitis C, 48 with systemic lupus erythematosus, 3 with cryptogenic hepatitis, and 40 normal controls were the subjects of the present study. Anti-SLA/LP autoantibodies were detected in only 5 of 75 (6.7%) patients with AIH type 1, but in none of the other 159 patients or 40 normal controls. The clinicopathologic features of anti-SLA/LP-positive AIH type 1, including carriers of HLA DR locus variations, were not significantly different from anti-SLA/LP-negative patients except for the mortality rate. Anti-SLA/LP autoantibody was detected at a low frequency in Japanese patients with AIH type 1 and did not significantly influence clinical features. However, since it has high disease-specificity to AIH type 1, further analysis of SLA/LP may contribute to help clarify the pathogenesis of AIH type 1.

  15. Lp(a-cholesterol is associated with HDL-cholesterol in overweight and obese African American children and is not an independent risk factor for CVD

    Directory of Open Access Journals (Sweden)

    Sharma Sushma

    2012-01-01

    Full Text Available Abstract Background The role of Lipoprotein (a cholesterol {Lp(a-C}as an additional and/or independent risk factor for cardiovascular disease (CVD is not clear. We evaluated the associations between Lp(a-C and other CVD risk factors including plasma lipoprotein concentrations and body fatness in overweight and obese African American children. Methods A cross-sectional analysis was carried out using data from a sample of 121 African American children aged 9-11 years with Body Mass Index (BMI's greater than the 85th percentile. Body height, weight and waist circumference (WC were measured. Fasting plasma concentrations of Lp(a-C, Total cholesterol (TC, High density lipoprotein cholesterol (HDL-C, Very low density lipoprotein cholesterol (VLDL-C, Intermediate density lipoprotein cholesterol (IDL-C, Low density lipoprotein cholesterol (LDL-C, and Triacylglycerides (TAG were analyzed using the vertical auto profile (VAP cholesterol method. Results After adjusting for child age, gender, and pubertal status, Lp(a-C was positively associated with both HDL-C and TC, and negatively associated with VLDL-C and TAG. Including BMIz and WC as additional covariates did not alter the direction of the relationships between Lp(a-C and the other lipoproteins. Finally, after adjusting for the other plasma lipoproteins, Lp(a-C remained strongly associated with HDL-C, whereas the associations of Lp(a-C with the other lipoproteins were not significant when HDL-C was simultaneously included in the regression models. Conclusions Lp(a-C was positively associated with HDL-C and this association is not influenced by other lipoprotein subclasses or by the degree of obesity. We conclude that Lp(a cholesterol is not an independent risk factor for CVD in African American children.

  16. DETERMINE OF Lp-SOLUTION OR L∞-SOLUTION OF NONLINEAR EQUATION OF TWO ORDERS%二阶非线性微分方程解属于Lp[0,+∞)的判定

    Institute of Scientific and Technical Information of China (English)

    赵雪芹

    1999-01-01

    讨论方程(r(t)g(y(t))y′)1+c(t)f(y)y′+a(t)b(y)=0解的有界性,给出了几个方程解属于Lp[0,+∞)或有界的充分条件.所用方法不同于以往的V函数法,所得结论推广了前人的结论.

  17. Some extremal properties of multivariate polynomial splines in the metric Lp (Rd )

    Institute of Scientific and Technical Information of China (English)

    LlU; Yongping(

    2001-01-01

    [1]Li Chun, Infinite dimensional widths of function classes, J. Approx. Theory, 1992, 69(1): 15-34.[2]Luo Junbo, Liu Yongping, Average width and optimal recovery of some anisotropic classes of smooth functions defined on the Euclidean space Bd, Northeast Math. J. , 1999, 15(4): 423-432.[3]Schoenberg, I. J., Cardinal interpolation and spline functions Ⅱ. Interpolation of data of power growth, J. Approx. Theory, 1972, 6(4): 404-420.[4]Fang Gensun, Liu Yongping, Average width and optimal interpolation of the Sobolev-Wiener class Wpd (B) in the metric Lq(Y), J. Approx Theory, 1993, 74(3): 335-352.[5]Pinkus, A., N-widths in Approximation Theory, New York: Springer-Verlag, 1985.[6]Foumier, J. J. F., Stewart, J., Amalgams of Lp and lq, Bull. Amer. Math. Soc., 1985, 13(1): 1-12.

  18. Aerodynamic loading distribution effects on the overall performance of ultra-high-lift LP turbine cascades

    Science.gov (United States)

    Berrino, M.; Satta, F.; Simoni, D.; Ubaldi, M.; Zunino, P.; Bertini, F.

    2014-02-01

    The present paper reports the results of an experimental investigation aimed at comparing aerodynamic performance of three low-pressure turbine cascades for several Reynolds numbers under steady and unsteady inflows. This study is focused on finding design criteria useful to reduce both profile and secondary losses in the aero-engine LP turbine for the different flight conditions. The baseline blade cascade, characterized by a standard aerodynamic loading (Zw=1.03), has been compared with two Ultra-High-Lift profiles with the same Zweifel number (Zw=1.3 for both cascades), but different velocity peak positions, leading to front and mid-loaded blade cascade configurations. The aerodynamic flow fields downstream of the cascades have been experimentally investigated for Reynolds numbers in the range 70000plane downstream of the cascade for both inflow conditions. The analysis of the results allows the evaluation of the aerodynamic performance of the blade cascades in terms of profile and secondary losses and the understanding of the effects of loading distribution and Zweifel number on secondary flows. When operating under unsteady inflow, contrarily to the steady case, the mid-loaded cascade has been found to be characterized by the lowest profile and secondary losses, making it the most attractive solution for the design of blades working in real conditions where unsteady inflow effects are present.

  19. LP Well-Posedness for Bilevel Vector Equilibrium and Optimization Problems with Equilibrium Constraints

    Directory of Open Access Journals (Sweden)

    Phan Quoc Khanh

    2014-01-01

    Full Text Available The purpose of this paper is introduce several types of Levitin-Polyak well-posedness for bilevel vector equilibrium and optimization problems with equilibrium constraints. Base on criterion and characterizations for these types of Levitin-Polyak well-posedness we argue on diameters and Kuratowski’s, Hausdorff’s, or Istrǎtescus measures of noncompactness of approximate solution sets under suitable conditions, and we prove the Levitin-Polyak well-posedness for bilevel vector equilibrium and optimization problems with equilibrium constraints. Obtain a gap function for bilevel vector equilibrium problems with equilibrium constraints using the nonlinear scalarization function and consider relations between these types of LP well-posedness for bilevel vector optimization problems with equilibrium constraints and these types of Levitin-Polyak well-posedness for bilevel vector equilibrium problems with equilibrium constraints under suitable conditions; we prove the Levitin-Polyak well-posedness for bilevel equilibrium and optimization problems with equilibrium constraints.

  20. When LP is the Cure for Your Matching Woes: Improved Bounds for Stochastic Matchings

    CERN Document Server

    Bansal, Nikhil; Li, Jian; Mestre, Julian; Nagarajan, Viswanath; Rudra, Atri

    2010-01-01

    Consider a random graph model where each possible edge $e$ is present independently with some probability $p_e$. Given these probabilities, we want to build a large/heavy matching in the randomly generated graph. However, the only way we can find out whether an edge is present or not is to query it, and if the edge is indeed present in the graph, we are forced to add it to our matching. Further, each vertex $i$ is allowed to be queried at most $t_i$ times. How should we adaptively query the edges to maximize the expected weight of the matching? We consider several matching problems in this general framework (some of which arise in kidney exchanges and online dating, and others arise in modeling online advertisements); we give LP-rounding based constant-factor approximation algorithms for these problems. Our main results are the following: We give a 4 approximation for weighted stochastic matching on general graphs, and a 3 approximation on bipartite graphs. This answers an open question from [Chen etal ICALP ...