WorldWideScience

Sample records for unit activities general

  1. Participating in politics resembles physical activity: general action patterns in international archives, United States archives, and experiments.

    Science.gov (United States)

    Noguchi, Kenji; Handley, Ian M; Albarracín, Dolores

    2011-02-01

    A series of studies examined whether political participation can emerge from general patterns of indiscriminate activity. In the first two studies, general action tendencies were measured by combining national and state-level indicators of high activity (e.g., impulsiveness, pace of life, and physical activity) from international and U.S. data. This action-tendency index positively correlated with a measure of political participation that consisted of voting behaviors and participation in political demonstrations. The following two experimental studies indicated that participants exposed to action words (e.g., go, move) had stronger intentions to vote in an upcoming election and volunteered more time to make phone calls on behalf of a university policy than participants exposed to inaction words did (e.g., relax, stop). These studies suggest that political participation can be predicted from general tendencies toward activity present at the national and state levels, as well as from verbal prompts suggestive of activity.

  2. General human activity patterns

    CERN Document Server

    Mollgaard, Anders; Mathiesen, Joachim

    2016-01-01

    We investigate the dynamics and interplay between human communication, movement, and social proximity by analyzing data collected from smartphones distributed among 638 individuals. The main question we consider is: to what extent do individuals act according to patterns shared across an entire population? Based on statistics of the entire population, we successfully predict 71\\% of the activity and 85\\% of the inactivity involved in communication, movement, and social proximity. We find that individual level statistics only result in marginally better predictions, indicating a high degree of shared activity patterns across the population. Finally, we predict short-term activity patterns using a generalized linear model, which suggests that a simple linear description might be sufficient to explain a wide range of actions, whether they be of social or of physical character.

  3. Taxation of United States general aviation

    Science.gov (United States)

    Sobieralski, Joseph Bernard

    General aviation in the United States has been an important part of the economy and American life. General aviation is defined as all flying excluding military and scheduled airline operations, and is utilized in many areas of our society. The majority of aircraft operations and airports in the United States are categorized as general aviation, and general aviation contributes more than one percent to the United States gross domestic product each year. Despite the many benefits of general aviation, the lead emissions from aviation gasoline consumption are of great concern. General aviation emits over half the lead emissions in the United States or over 630 tons in 2005. The other significant negative externality attributed to general aviation usage is aircraft accidents. General aviation accidents have caused over 8000 fatalities over the period 1994-2006. A recent Federal Aviation Administration proposed increase in the aviation gasoline tax from 19.4 to 70.1 cents per gallon has renewed interest in better understanding the implications of such a tax increase as well as the possible optimal rate of taxation. Few studies have examined aviation fuel elasticities and all have failed to study general aviation fuel elasticities. Chapter one fills that gap and examines the elasticity of aviation gasoline consumption in United States general aviation. Utilizing aggregate time series and dynamic panel data, the price and income elasticities of demand are estimated. The price elasticity of demand for aviation gasoline is estimated to range from -0.093 to -0.185 in the short-run and from -0.132 to -0.303 in the long-run. These results prove to be similar in magnitude to automobile gasoline elasticities and therefore tax policies could more closely mirror those of automobile tax policies. The second chapter examines the costs associated with general aviation accidents. Given the large number of general aviation operations as well as the large number of fatalities and

  4. Modeling of active beam units with Modelica

    DEFF Research Database (Denmark)

    Maccarini, Alessandro; Hultmark, Göran; Vorre, Anders

    2015-01-01

    This paper proposes an active beam model suitable for building energy simulations with the programming language Modelica. The model encapsulates empirical equations derived by a novel active beam terminal unit that operates with low-temperature heating and high-temperature cooling systems....... Measurements from a full-scale experiment are used to compare the thermal behavior of the active beam with the one predicted by simulations. The simulation results show that the model corresponds closely with the actual operation. The model predicts the outlet water temperature of the active beam...... with a maximum mean absolute error of 0.18 °C. In term of maximum mean absolute percentage error, simulation results differ by 0.9%. The methodology presented is general enough to be applied for modeling other active beam units. Modeling of active beam units with Modelica. Available from: https...

  5. 12 CFR 561.53 - United States Treasury General Account.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false United States Treasury General Account. 561.53 Section 561.53 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY DEFINITIONS FOR REGULATIONS AFFECTING ALL SAVINGS ASSOCIATIONS § 561.53 United States Treasury General Account. The...

  6. NCHS - Births and General Fertility Rates: United States

    Data.gov (United States)

    U.S. Department of Health & Human Services — This dataset includes crude birth rates and general fertility rates in the United States since 1909. The number of states in the reporting area differ historically....

  7. Use of general purpose graphics processing units with MODFLOW.

    Science.gov (United States)

    Hughes, Joseph D; White, Jeremy T

    2013-01-01

    To evaluate the use of general-purpose graphics processing units (GPGPUs) to improve the performance of MODFLOW, an unstructured preconditioned conjugate gradient (UPCG) solver has been developed. The UPCG solver uses a compressed sparse row storage scheme and includes Jacobi, zero fill-in incomplete, and modified-incomplete lower-upper (LU) factorization, and generalized least-squares polynomial preconditioners. The UPCG solver also includes options for sequential and parallel solution on the central processing unit (CPU) using OpenMP. For simulations utilizing the GPGPU, all basic linear algebra operations are performed on the GPGPU; memory copies between the central processing unit CPU and GPCPU occur prior to the first iteration of the UPCG solver and after satisfying head and flow criteria or exceeding a maximum number of iterations. The efficiency of the UPCG solver for GPGPU and CPU solutions is benchmarked using simulations of a synthetic, heterogeneous unconfined aquifer with tens of thousands to millions of active grid cells. Testing indicates GPGPU speedups on the order of 2 to 8, relative to the standard MODFLOW preconditioned conjugate gradient (PCG) solver, can be achieved when (1) memory copies between the CPU and GPGPU are optimized, (2) the percentage of time performing memory copies between the CPU and GPGPU is small relative to the calculation time, (3) high-performance GPGPU cards are utilized, and (4) CPU-GPGPU combinations are used to execute sequential operations that are difficult to parallelize. Furthermore, UPCG solver testing indicates GPGPU speedups exceed parallel CPU speedups achieved using OpenMP on multicore CPUs for preconditioners that can be easily parallelized. Published 2013. This article is a U.S. Government work and is in the public domain in the USA.

  8. Recombinative generalization of subword units using matching to sample.

    LENUS (Irish Health Repository)

    Mahon, Catherine

    2010-01-01

    The purpose of the current study was to develop and test a computerized matching-to-sample (MTS) protocol to facilitate recombinative generalization of subword units (onsets and rimes) and recognition of novel onset-rime and onset-rime-rime words. In addition, we sought to isolate the key training components necessary for recombinative generalization. Twenty-five literate adults participated. Conditional discrimination training emerged as a crucial training component. These findings support the effectiveness of MTS in facilitating recombinative generalization, particularly when conditional discrimination training with subword units is used.

  9. The ATLAS Trigger Algorithms for General Purpose Graphics Processor Units

    CERN Document Server

    Tavares Delgado, Ademar; The ATLAS collaboration

    2016-01-01

    The ATLAS Trigger Algorithms for General Purpose Graphics Processor Units Type: Talk Abstract: We present the ATLAS Trigger algorithms developed to exploit General­ Purpose Graphics Processor Units. ATLAS is a particle physics experiment located on the LHC collider at CERN. The ATLAS Trigger system has two levels, hardware-­based Level 1 and the High Level Trigger implemented in software running on a farm of commodity CPU. Performing the trigger event selection within the available farm resources presents a significant challenge that will increase future LHC upgrades. are being evaluated as a potential solution for trigger algorithms acceleration. Key factors determining the potential benefit of this new technology are the relative execution speedup, the number of GPUs required and the relative financial cost of the selected GPU. We have developed a trigger demonstrator which includes algorithms for reconstructing tracks in the Inner Detector and Muon Spectrometer and clusters of energy deposited in the Cal...

  10. Automatic movie skimming with story units via general tempo analysis

    Science.gov (United States)

    Lee, Shih-Hung; Yeh, Chia H.; Kuo, C.-C. J.

    2003-12-01

    A skimming system for movie content exploration is proposed using story units extracted via general tempo analysis of audio and visual data. Quite a few schemes have been proposed to segment video data into shots with low-level features, yet the grouping of shots into meaningful units, called story units here, is important and challenging. In this work, we detect similar shots using key frames and include these similar shots as a node in the scene transition graph. Then, an importance measure is calculated based on the total length of each node. Finally, we select sinks and shots according to this measure. Based on these semantic shots, a meaningful skims can be successfully generated. Simulation results will be presented to show that the proposed video skimming scheme can preserve the essential and significant content of the original video data.

  11. Improving the smoking patterns in a general hospital psychiatric unit

    OpenAIRE

    Celso Iglesias García; María José Alonso Villa; Juan Carlos Bernaldo de Quirós; Elena Bocanegra Suárez; Julia Cueta Gonzalo; Rosario García del Valle; José Manuel González González; Álvaro Miranda García; Ana Belén Palacio Bande

    2009-01-01

    Objectives: The purpose of the present paper is to evaluate the effects of a smoking ban in a general hospital psychiatric unit. Methods: We study the effects of smoking ban in 40 consecutive psychiatric inpatients. The staff registered socio-demographic and tobacco-related variables. We also registered any kind of behavioral effects of smoking ban.Results: The patients were willing to stop smoking during their hospital stay (with or without nicotine replacement) with two mild behavioural inc...

  12. 41 CFR 105-50.001-3 - Unit of general local government.

    Science.gov (United States)

    2010-07-01

    ... TECHNICAL SERVICES TO STATE AND LOCAL UNITS OF GOVERNMENT § 105-50.001-3 Unit of general local government. Unit of general local government means any city, county, town, parish, village, or other general... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Unit of general...

  13. Improving the smoking patterns in a general hospital psychiatric unit

    Directory of Open Access Journals (Sweden)

    Celso Iglesias García

    2009-01-01

    Full Text Available Objectives: The purpose of the present paper is to evaluate the effects of a smoking ban in a general hospital psychiatric unit. Methods: We study the effects of smoking ban in 40 consecutive psychiatric inpatients. The staff registered socio-demographic and tobacco-related variables. We also registered any kind of behavioral effects of smoking ban.Results: The patients were willing to stop smoking during their hospital stay (with or without nicotine replacement with two mild behavioural incidences registered throughout the study. Conclusions: The benefits of non-smoking policy in a psychiatric unit can be significant. The introduction of smoking bans in psychiatric inpatients settings is possible and safe.

  14. General care plan in a Paediatric Intensive Care Unit

    Directory of Open Access Journals (Sweden)

    Mª Teresa Martín Alonso

    2011-07-01

    Full Text Available The care plan we expose is a general one applicable to all the children who are admitted in the unit, no matter what pathology they present/display, their physiopathological situation or their age. We present the common nursing actions which are applied to all the patients at the time of their admittance. The factor related to the studied problems is the hospitalization and what it has associate, from separation of the parents and rupture familiar ties, up to immobilization, the use of bloody devices and the generally hostile and stranger background.The protocol is based on the NANDA, the nursing outcomes classification NOC and the nursing intervention classification NIC. It is part of the nursing process and promotes systematized, humanistic and effective care, focuses on the child and his parents.We have selected the most relevant problems, ordered according to the deficits in the different selfcare requirements of Dorotea E. Orem. Each problem has its definition, the outcomes we pretend to reach with our care and the interventions to get the outcomes (these two last topics have the corresponding codification. In them all the most important factor is hospitalization in a unit of intensive care and the separation of the child from his habitual environment.

  15. Measuring Cognitive Translation Effort with Activity Units

    DEFF Research Database (Denmark)

    Schaeffer, Moritz; Carl, Michael; Lacruz, Isabel

    2016-01-01

    Despite the increased quality of Machine Translation output, human interaction will remain a crucial activity to guarantee the quality of the final translation products. Human-computer interaction in translation will likely be the more successful the more we understand the properties and compleme...... methods in empirical translation process research and suggests ngrams of Activity Units for measuring the translation process....

  16. GENETIC ALGORITHM ON GENERAL PURPOSE GRAPHICS PROCESSING UNIT: PARALLELISM REVIEW

    Directory of Open Access Journals (Sweden)

    A.J. Umbarkar

    2013-01-01

    Full Text Available Genetic Algorithm (GA is effective and robust method for solving many optimization problems. However, it may take more runs (iterations and time to get optimal solution. The execution time to find the optimal solution also depends upon the niching-technique applied to evolving population. This paper provides the information about how various authors, researchers, scientists have implemented GA on GPGPU (General purpose Graphics Processing Units with and without parallelism. Many problems have been solved on GPGPU using GA. GA is easy to parallelize because of its SIMD nature and therefore can be implemented well on GPGPU. Thus, speedup can definitely be achieved if bottleneck in GAs are identified and implemented effectively on GPGPU. Paper gives review of various applications solved using GAs on GPGPU with the future scope in the area of optimization.

  17. [Crisis unit at the general hospital: Determinants of further hospitalization].

    Science.gov (United States)

    Norotte, C; Omnès, C; Crozier, C; Verlyck, C; Romanos, M

    2016-10-10

    The availability of short-stay beds for brief admission (less than 72hours) of crisis patients presenting to the emergency room is a model that has gained a growing interest because it allows time for developing alternatives to psychiatric hospitalization and favors a maintained functioning in the community. Still, the determinants influencing the disposition decision at discharge after crisis intervention remain largely unexplored. The primary objective of this study was to determine the factors predicting aftercare dispositions at crisis unit discharge: transfer for further hospitalization or return to the community. Secondary objectives included the description of clinical and socio-demographic characteristics of patients admitted to the crisis unit upon presentation to the emergency room. All patients (n=255) admitted to the short-stay unit of the emergency department of Rambouillet General Hospital during a one-year period were included in the study. Patient characteristics were collected in a retrospective manner from medical records: patterns of referral, acute stressors, presenting symptoms, initial patient demand, Diagnostic and Statistical Manual, 5th edition (DSM-5) disorders, psychiatric history, and socio-demographic characteristics were inferred. Logistic regression analysis was used to determine the factors associated with hospitalization decision upon crisis intervention at discharge. Following crisis intervention at the short-stay unit, 100 patients (39.2%) required further hospitalization and were transferred. Statistically significant factors associated with a higher probability of hospitalization (P<0.05) included the patient's initial wish to be hospitalized (OR=4.28), the presence of a comorbid disorder (OR=3.43), a referral by family or friends (OR=2.89), a history of psychiatric hospitalization (OR=2.71) and suicidal ideation on arrival in the emergency room (OR=2.26). Conversely, significant factors associated with a lower probability of

  18. Clinical Activity in General Practice and Cancer

    DEFF Research Database (Denmark)

    Hjertholm, Peter

    2015-01-01

    BACKGROUND AND AIMS Cancer is a common, serious disease and early diagnosis is a cornerstone in the effort to improve the outcome from cancer disease. The general practitioner (GP) plays a crucial role in achieving this goal. Little is known about GPs’ suspicion of cancer and the activities the GPs...... institute in relation to such suspicion. Knowledge is also sparse on any effects of different diagnostic activities in general practice. The overall aims of this thesis were therefore: -to describe how often Danish GPs suspected cancer or other serious diseases and how they acted on the suspicion......, and to analyse how a suspicion influenced the demand for health care services and predicted a future diagnosis of serious disease - to investigate whether variation in GPs’ diagnostic activity influences cancer patients’ prognosis in relation to prostate-specific antigen (PSA) testing and prostate cancer...

  19. Wind Lidar Activities in the United States

    Energy Technology Data Exchange (ETDEWEB)

    Clifton, Andrew; Newman, Jennifer; St. Pe, Alexandra; Iungo, G. Valerio; Wharton, Sonia; Herges, Tommy; Filippelli, Matthew; Pontbriand, Philippe; Osler, Evan

    2017-06-28

    IEA Wind Task 32 seeks to identify and mitigate the barriers to the adoption of lidar for wind energy applications. This work is partly achieved by sharing experience across researchers and practitioners in the United States and worldwide. This presentation is a short summary of some wind lidar-related activities taking place in the country, and was presented by Andrew Clifton at the Task 32 meeting in December 2016 in his role as the U.S. Department of Energy-nominated country representative to the task.

  20. Perceptions of a disability sport unit in general physical education.

    Science.gov (United States)

    Grenier, Michelle; Collins, Karen; Wright, Steven; Kearns, Catherine

    2014-01-01

    The purpose of this qualitative study was to assess the effectiveness of a disability sport unit in shaping perceptions of disability. Data from interviews, observations, and documents were collected on 87 elementary-aged students, one physical education teacher, and one teaching intern. Comparisons were drawn between fifth graders engaged in a five-week disability sport unit to fourth graders participating in their standard physical education curriculum. Findings revealed differences in the way fourth and fifth graders came to view individuals with disabilities. The results support an analysis of curriculum development that underscores the significance of the social model in positively impacting constructions of disability. Recommendations include the use of disability sports in physical education as an effective strategy for educating students in game play, knowledge of the Paralympics, and the inclusion of individuals with disabilities in a variety of sporting venues.

  1. Generalized trust and intelligence in the United States.

    Science.gov (United States)

    Carl, Noah; Billari, Francesco C

    2014-01-01

    Generalized trust refers to trust in other members of society; it may be distinguished from particularized trust, which corresponds to trust in the family and close friends. An extensive empirical literature has established that generalized trust is an important aspect of civic culture. It has been linked to a variety of positive outcomes at the individual level, such as entrepreneurship, volunteering, self-rated health, and happiness. However, two recent studies have found that it is highly correlated with intelligence, which raises the possibility that the other relationships in which it has been implicated may be spurious. Here we replicate the association between intelligence and generalized trust in a large, nationally representative sample of U.S. adults. We also show that, after adjusting for intelligence, generalized trust continues to be strongly associated with both self-rated health and happiness. In the context of substantial variation across countries, these results bolster the view that generalized trust is a valuable social resource, not only for the individual but for the wider society as well.

  2. Generalized trust and intelligence in the United States.

    Directory of Open Access Journals (Sweden)

    Noah Carl

    Full Text Available Generalized trust refers to trust in other members of society; it may be distinguished from particularized trust, which corresponds to trust in the family and close friends. An extensive empirical literature has established that generalized trust is an important aspect of civic culture. It has been linked to a variety of positive outcomes at the individual level, such as entrepreneurship, volunteering, self-rated health, and happiness. However, two recent studies have found that it is highly correlated with intelligence, which raises the possibility that the other relationships in which it has been implicated may be spurious. Here we replicate the association between intelligence and generalized trust in a large, nationally representative sample of U.S. adults. We also show that, after adjusting for intelligence, generalized trust continues to be strongly associated with both self-rated health and happiness. In the context of substantial variation across countries, these results bolster the view that generalized trust is a valuable social resource, not only for the individual but for the wider society as well.

  3. Detailed Analysis of Motor Unit Activity

    DEFF Research Database (Denmark)

    Nikolic, Mile; Sørensen, John Aasted; Dahl, Kristian

    1997-01-01

    System for decomposition of EMG signals intotheir constituent motor unit potentials and their firing patterns.The aim of the system is detailed analysis ofmotor unit variability.......System for decomposition of EMG signals intotheir constituent motor unit potentials and their firing patterns.The aim of the system is detailed analysis ofmotor unit variability....

  4. Detailed Analysis of Motor Unit Activity

    DEFF Research Database (Denmark)

    Nikolic, Mile; Sørensen, John Aasted; Dahl, Kristian

    1997-01-01

    System for decomposition of EMG signals intotheir constituent motor unit potentials and their firing patterns.The aim of the system is detailed analysis ofmotor unit variability.......System for decomposition of EMG signals intotheir constituent motor unit potentials and their firing patterns.The aim of the system is detailed analysis ofmotor unit variability....

  5. United Nations Secretary General’s Peacekeeping Proposals

    Science.gov (United States)

    1993-04-06

    have undertaken to make available to the Security Council, on its call, " armed forces, assistance and facilities, and rights of passage , necessary...readiness and general locations and the nature of facilities and assistance, including rights of passage , to be made available to the Security

  6. 24 CFR 291.505 - Definition of “unit of general local government.”

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Definition of âunit of general local government.â 291.505 Section 291.505 Housing and Urban Development Regulations Relating to Housing... local government.” For purposes of this subpart, the term unit of general local government means...

  7. 43 CFR 44.56 - How does a unit of general local government file a protest?

    Science.gov (United States)

    2010-10-01

    ... FINANCIAL ASSISTANCE, LOCAL GOVERNMENTS State and Local Governments' Responsibilities After the Department Distributes Payments § 44.56 How does a unit of general local government file a protest? The protesting local... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false How does a unit of general...

  8. Should the United States Army Have a Professional General Staff?

    Science.gov (United States)

    1987-03-23

    Individual Study Project S. PERFORMING ORG. REPORT NUMBER 7. AUTHOR(.) S. CONTRACT OR GRANT NUMBER(&) COL Bradley H. Petersen Jr. , AR 9. PERFORMING...diagrams" seldom tell us mucL about how business is really accomplished. All potential threat and free world forces are privy to or in posession of the...the Germans lost despite this operationri 17 brilliance because of strategic incompetence. 7here is mucl to, indicate that the German General Staff

  9. Prediktor Stres Keluarga Akibat Anggota Keluarganya Dirawat di General Intensive Care Unit

    Directory of Open Access Journals (Sweden)

    Zahara Farhan

    2014-09-01

    Full Text Available Hospitalization of family member in intensive care can be a trigger of stress in the family. Several factors which could create a stressful situation in a family are changes of environment, rules in the ward, changes of family emotional status, changes of family member roles, changes of daily activities, changes in financial situation and health care workers' attitude when giving information on patient’s health status. This study was a cross-sectional study. The number of subjects included in this study were 60 representing families whose member was hospitalized in the General Intensive Care Unit (GICU of Dr. Hasan Sadikin General Hospital (RSHS Bandung during the period of March to May 2012. The sampling technique used was purposive sampling. The instrument used to measure the stress predictors was developed based on theoretical review and modification of family inventory live events standard instrument. Meanwhile, the instrument used for measuring the family stress was the Depression Anxiety Stress Scale 42. Data were analyzed using chi-square test and logistic regression. The results of this study showed environmental changes, rules in the ward, emotional status changes and daily activity changes significantly corelated with stress (p value 0.01, 0.04 and 0.03, respectively. In conclusion, none of the 6 family predictors dominantly predicts stress. Nurses are expected to do early detection on psychological family problems in intensive care unit and optimize supportive-educative treatment in the form of counseling for family members.

  10. Prospective study on sociodynamics of cellulitis in general surgical unit

    Directory of Open Access Journals (Sweden)

    Didde Sundara Chakravarthy

    2015-05-01

    Results: The median age of the participants was 62.5 years. The following risk factors were strongly and independently associated with cellulitis and outcome of the patient; illiteracy (OR, 4; P value 0.010, age above 50 years (OR, 0.110; P value 0.000, residing in rural areas (OR, 4.008; P value 0.006, low socioeconomic status (OR, 0.241; P value 0.030 and associated co-morbid conditions (OR, 0.390; P value, 0.032. Conclusion: Patients usually presented in the late stage of disease because of illiteracy, ignorance and poor knowledge. Patients should be educated to routinely inspect their feet, and the importance of appropriate footwear should be emphasized. Patients who are actively involved in their care can improve their quality of life and have a better outcome. [Int J Res Med Sci 2015; 3(5.000: 1052-1055

  11. 20 CFR 404.1573 - General information about work activity.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false General information about work activity. 404... DISABILITY INSURANCE (1950- ) Determining Disability and Blindness Substantial Gainful Activity § 404.1573 General information about work activity. (a) The nature of your work. If your duties require use of...

  12. 20 CFR 220.142 - General information about work activity.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false General information about work activity. 220... RETIREMENT ACT DETERMINING DISABILITY Substantial Gainful Activity § 220.142 General information about work activity. (a) The nature of the claimant's work. If the claimant's duties require use of the...

  13. 20 CFR 416.973 - General information about work activity.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false General information about work activity. 416... FOR THE AGED, BLIND, AND DISABLED Determining Disability and Blindness Substantial Gainful Activity § 416.973 General information about work activity. (a) The nature of your work. If your duties...

  14. Ambient Cured Alkali Activated Flyash Masonry Units

    Science.gov (United States)

    Venugopal, K.; Radhakrishna; Sasalatti, Vinod M.

    2016-09-01

    Geopolymers belong to a category of non-conventional and non-Portland cement based cementitious binders which are produced using industrial by products like fly ash and ground granulated blast furnace slag (GGBFS). This paper reports on the development of geopolymer mortars for production of masonry units. The geopolymer mortars were prepared by mixing various by products with manufactured sand and a liquid mixture of sodium silicate and sodium hydroxide solutions. After curing at ambient conditions, the masonry units were tested for strength properties such as water absorption, initial rate of absorption, compression, shear- bond, and stress-strain behaviour etc. It was observed that the flexural strength of the blocks is more than 2 MPa and shear bond strength is more than 0.4MPa. It was found that the properties of geopolymer blocks were superior to the traditional masonry units. Hence they can be recommended for structural masonry.

  15. Graduate education in general surgery and its related specialties and subspecialties in the United States.

    Science.gov (United States)

    Bell, Richard H

    2008-10-01

    Each year, approximately 1,000 graduating medical students enter training in general surgery and its related specialties and subspecialties in the United States. Traditionally, residents who want to practice vascular surgery, plastic surgery, thoracic surgery, and other specialties and subspecialties derived from general surgery have been required to complete five years of training in general surgery before embarking on further training. However, three phenomena have recently emerged that are changing the picture of surgical training: (1) proliferation of fellowships in subspecialties of general surgery, (2) increasing desire of subspecialties of general surgery for recognition as specialties in their own right, and (3) pressure to reduce or eliminate the traditional general surgery training required before specialization or subspecialization. In the meantime, and perhaps as a consequence of these changes, traditional general surgery has become less attractive as a specialty and there has been significant concern about the quality of training in general surgery. As a result of fewer trainees electing general surgery as a career, there is now increasing evidence of a shortage of surgeons who are able to handle a reasonably broad caseload of emergency care in general surgery and trauma.Many of these issues are currently being addressed by the profession. Among the initiatives underway are developing a standardized curriculum in general surgery, appropriately apportioning operative experience between residency and fellowship, considering alternative pathways for training in subspecialties, and developing a system for oversight of advanced surgical training fellowships. The system for governance of graduate surgical education in the United States is less centralized than in other countries. One initiative that has been undertaken to improve coordination of efforts between educational and regulatory bodies is the formation of the Surgical Council on Resident Education

  16. Care of severe head injury patients in the Sarawak General Hospital: intensive care unit versus general ward.

    Science.gov (United States)

    Sim, S K; Lim, S L; Lee, H K; Liew, D; Wong, A

    2011-06-01

    Intensive care for severe head injury patients is very important in the prevention and treatment of secondary brain injury. However, in a resources constraint environment and limited availability of Intensive Care Unit (ICU) beds in the hospitals, not all severe head injury patients will receive ICU care. This prospective study is aimed to evaluate the outcome of severe head injured patients who received ICU and general ward care in Sarawak General Hospital (SGH) over a 6-month period. A total of thirty five severe head injury patients were admitted. Twenty three patients (65.7%) were ventilated in general ward whereas twelve patients (34.3%) were ventilated in ICU. Overall one month mortality in this study was 25.7%. Patients who received ICU care had a lower one month mortality than those who received general ward care (16.7% vs 30.4%), although it was not statistically different. Multivariate analysis revealed only GCS on admission (OR 0.731; 95% CI 0.460 to 0.877; P=0.042) as the independent predictive factor for one month mortality in this study.

  17. Assessment of the early effectiveness of a stroke unit in comparison to the general ward

    Institute of Scientific and Technical Information of China (English)

    马锐华; 王拥军; 曲辉; 杨中华

    2004-01-01

    Background Stroke unit is the most effective treatment method to benefit stroke patients. Our study is to evaluate the early effectiveness of a hospital stroke unit (SU). Methods Three hundred and ninety-two patients who had suffered from acute strokes and who were admitted to our hospital between December 2001 and January 2003 were recruited for this controlled study. All patients were sent at random to either the SU or the general ward (GW) for treatment. The following indices were measured by: Barthel Index (BI), National Institute of Health Stroke Scale (NIHSS), Oxford Handicap Scale (OHS). Results The mean change in BI score between the day of admission and the day of discharge was 20.00±24.36 for the SU group and 10.63±23.59 for the GW group. A difference that is statistically significant (P=0.000). The mean change in NIHSS score was -2.01±6.61 for the SU group and 0.55±7.44 for the GW group. A difference that is also statistically significant (P=0.000). Finally, the mean change in OHS score was -0.74±1.04 for the SU group and -0.28±0.98 for the GW group, also a statistically significant difference (P=0.000). Among SU patients, patient satisfaction was higher (P=0.000), the rehabilitation success rate was higher (P=0.000), and there were fewer complications (P=0.000).Conclusion Compared to GW patients, stroke patients treated in a special SU were able to return to normal daily activities earlier, with better social abilities, and have reduced neurological defects, without increasing the overall economic burden.

  18. Developing an Industry-Education Community: The United Auto Workers/General Motors Quality Educator Program

    Science.gov (United States)

    Jacobson, Stephen; Walline, James

    2010-01-01

    In this paper we review the evolution of the Quality Educator Program (QEP), a program sponsored by the United Auto Workers (UAW)/General Motors (GM) that employs school teachers, administrators, and college and university faculty each summer in GM assembly plants. The QEP provides educators and those in industry the unique opportunity to interact…

  19. CMS Grid Activities in the United States

    Institute of Scientific and Technical Information of China (English)

    I.Fisk; J.Amundson; 等

    2001-01-01

    The CMS groups in the USA are actively involved in several grid-elated projects,including the DoE-funded Particle Physics Data Grid(PPDG)and the NSFfunded Grid Physics Network(GriPhyN).We present developments of :the Grid data Management Pilot (GDMP) software;a Java Analysis Studio-based prototype remote analysis service for CMS data;tools for automating job submission schemes for large scale distributed simulation and reconstruction runs for CMS;modeling and development of job scheduling schemes using the MONARC toolkit;a robust execution service for distributed processors.The deployment and use of these tools at prototype Tier1 and Tier2 computing centers in the USA is described.

  20. Perceiving the General: The Multisemiotic Dimension of Students' Algebraic Activity

    Science.gov (United States)

    Radford, Luis; Bardino, Caroline; Sabena, Cristina

    2007-01-01

    In this article, we deal with students' algebraic generalizations set in the context of elementary geometric-numeric patterns. Drawing from Vygotsky's psychology, Leont'ev's Activity Theory, and Husserl's phenomenology, we focus on the various semiotic resources mobilized by students in their passage from the particular to the general. Two small…

  1. Perceiving the General: The Multisemiotic Dimension of Students' Algebraic Activity

    Science.gov (United States)

    Radford, Luis; Bardino, Caroline; Sabena, Cristina

    2007-01-01

    In this article, we deal with students' algebraic generalizations set in the context of elementary geometric-numeric patterns. Drawing from Vygotsky's psychology, Leont'ev's Activity Theory, and Husserl's phenomenology, we focus on the various semiotic resources mobilized by students in their passage from the particular to the general. Two small…

  2. A generalized method of active RC network synthesis.

    Science.gov (United States)

    Leach, D. P.; Chan, S.-P.

    1971-01-01

    A completely general active RC network synthesis technique using a grounded gyrator and a summing amplifier is described. The technique overcomes serious limitations of previous RC-gyrator realizations and offers advantages o ver other general active RC synthesis methods. The technique is well suited for construction using thin-film RC networks and integrated circuit operational amplifiers, and provides a configuration which is quite insensitive to element variations.

  3. 12 CFR 347.113 - Restrictions applicable to activities by a foreign organization in the United States.

    Science.gov (United States)

    2010-01-01

    ... foreign organization engages in the United States are incidental to its international or foreign business... representative office. (2) The following activities are incidental to international or foreign business: (i... INSURANCE CORPORATION REGULATIONS AND STATEMENTS OF GENERAL POLICY INTERNATIONAL BANKING §...

  4. Dual and chiral objects for optical activity in general scattering directions

    CERN Document Server

    Fernandez-Corbaton, Ivan; Rockstuhl, Carsten

    2016-01-01

    Optically active artificial structures have attracted tremendous research attention. Such structures must meet two requirements: Lack of spatial inversion symmetries and, a condition usually not explicitly considered, the structure shall preserve the helicity of light, which implies that there must be a vanishing coupling between the states of opposite polarization handedness among incident and scattered plane waves. Here, we put forward and demonstrate that a unit cell made from chiraly arranged electromagnetically dual scatterers serves exactly this purpose. We prove this by demonstrating optical activity of such unit cell in general scattering directions.

  5. DRUG MANAGEMENT REVIEWS IN DISTRICT DRUG MANAGEMENT UNIT AND GENERAL HOSPITAL

    Directory of Open Access Journals (Sweden)

    Max Joseph Herman

    2009-12-01

    Full Text Available Drug is one of the essential elements in healthcare that should be effectively and efficiently managed. Following thedecentralization in 2001 in Indonesia, drug management has changed in district drug management units and also in District General Hospitals. Certainly this condition influences the sustainability of drug access in primary health care such as in Community Health Center and District General Hospital, especially in drug financing policy. A cross sectional descriptive study to obtain information on drug management in public healthcare in district had been carried out between July and December 2006 in 10 District Public Drug Management Units from 10 district health offices and 9 district general hospitals as samples. Data were collected by interviewing heads of Drug Section in District Health Offices and heads of Hospital Pharmacies using structured questionnaires and observing drug storage in District Drug Management Units, Community Health Centers, and Hospital Pharmacies. Results of the study show that drug planning in District Health Offices and General Hospitals did not meet the basic real need in some districts nor District Hospitals. The minimum health service standards had no been achieved yet. Furthermore, drug procurement, storage and recording as well as reporting was not good enough either, such as shown by the existence of expired drugs. Lead time for drug delivery to community health centers in some districts was longer than the average of lead time in the past 3 years.

  6. Teaching emotional intelligence to intensive care unit nurses and their general health: a randomized clinical trial.

    Science.gov (United States)

    Sharif, F; Rezaie, S; Keshavarzi, S; Mansoori, P; Ghadakpoor, S

    2013-07-01

    Emotion and how people manage it is an important part of personality that would immensely affect their health. Investigations showed that emotional intelligence is significantly related to and can predict psychological health. To determine the effect of teaching emotional intelligence to intensive care unit nurses on their general health. This randomized clinical trial (registered as IRCT201208022812N9) was conducted on 52 of 200 in intensive care unit nurses affiliated to Shiraz University of Medical Sciences. They were recruited through purposeful convenience sampling and then randomly categorized into two groups. The intervention group members were trained in emotional intelligence. Bar-on emotional intelligence and Goldberg's general health questionnaires were administered to each participant before, immediately after, and one month after the intervention. While the mean score of general health for the intervention group decreased from 25.4 before the intervention, to 18.1 immediately after the intervention and to 14.6 one month later, for the control group, it increased from 22.0, to 24.2 and to 26.5, respectively (pTeaching emotional intelligence improved the general health of intensive care unit nurses.

  7. Teaching Emotional Intelligence to Intensive Care Unit Nurses and their General Health: A Randomized Clinical Trial

    Directory of Open Access Journals (Sweden)

    F Sharif

    2013-07-01

    Full Text Available Background: Emotion and how people manage it is an important part of personality that would immensely affect their health. Investigations showed that emotional intelligence is significantly related to and can predict psychological health. Objective: To determine the effect of teaching emotional intelligence to intensive care unit nurses on their general health. Methods: This randomized clinical trial (registered as IRCT201208022812N9 was conducted on 52 of 200 in intensive care unit nurses affiliated to Shiraz University of Medical Sciences. They were recruited through purposeful convenience sampling and then randomly categorized into two groups. The intervention group members were trained in emotional intelligence. Bar-on emotional intelligence and Goldberg's general health questionnaires were administered to each participant before, immediately after, and one month after the intervention. Results: While the mean score of general health for the intervention group decreased from 25.4 before the intervention, to 18.1 immediately after the intervention and to 14.6 one month later, for the control group, it increased from 22.0, to 24.2 and to 26.5, respectively (p<0.001. Conclusion: Teaching emotional intelligence improved the general health of intensive care unit nurses.

  8. Promotion of nutrition and physical activity in Dutch general practice

    NARCIS (Netherlands)

    Dillen, van S.; Hiddink, G.J.; Woerkum, van C.M.J.

    2011-01-01

    Introduction: Promotion of nutrition and physical activity is important to slow down the increase of overweight. General practitioners (GPs) are in an unique position to communicate with their patients about nutrition and physical activity, because of the high referral score, high perceived expertis

  9. Applying activity-based costing to the nuclear medicine unit.

    Science.gov (United States)

    Suthummanon, Sakesun; Omachonu, Vincent K; Akcin, Mehmet

    2005-08-01

    Previous studies have shown the feasibility of using activity-based costing (ABC) in hospital environments. However, many of these studies discuss the general applications of ABC in health-care organizations. This research explores the potential application of ABC to the nuclear medicine unit (NMU) at a teaching hospital. The finding indicates that the current cost averages 236.11 US dollars for all procedures, which is quite different from the costs computed by using ABC. The difference is most significant with positron emission tomography scan, 463 US dollars (an increase of 96%), as well as bone scan and thyroid scan, 114 US dollars (a decrease of 52%). The result of ABC analysis demonstrates that the operational time (machine time and direct labour time) and the cost of drugs have the most influence on cost per procedure. Clearly, to reduce the cost per procedure for the NMU, the reduction in operational time and cost of drugs should be analysed. The result also indicates that ABC can be used to improve resource allocation and management. It can be an important aid in making management decisions, particularly for improving pricing practices by making costing more accurate. It also facilitates the identification of underutilized resources and related costs, leading to cost reduction. The ABC system will also help hospitals control costs, improve the quality and efficiency of the care they provide, and manage their resources better.

  10. Real-time radar signal processing using GPGPU (general-purpose graphic processing unit)

    Science.gov (United States)

    Kong, Fanxing; Zhang, Yan Rockee; Cai, Jingxiao; Palmer, Robert D.

    2016-05-01

    This study introduces a practical approach to develop real-time signal processing chain for general phased array radar on NVIDIA GPUs(Graphical Processing Units) using CUDA (Compute Unified Device Architecture) libraries such as cuBlas and cuFFT, which are adopted from open source libraries and optimized for the NVIDIA GPUs. The processed results are rigorously verified against those from the CPUs. Performance benchmarked in computation time with various input data cube sizes are compared across GPUs and CPUs. Through the analysis, it will be demonstrated that GPGPUs (General Purpose GPU) real-time processing of the array radar data is possible with relatively low-cost commercial GPUs.

  11. Prediction of chronic critical illness in a general intensive care unit

    Directory of Open Access Journals (Sweden)

    Sérgio H. Loss

    2013-06-01

    Full Text Available OBJECTIVE: To assess the incidence, costs, and mortality associated with chronic critical illness (CCI, and to identify clinical predictors of CCI in a general intensive care unit. METHODS: This was a prospective observational cohort study. All patients receiving supportive treatment for over 20 days were considered chronically critically ill and eligible for the study. After applying the exclusion criteria, 453 patients were analyzed. RESULTS: There was an 11% incidence of CCI. Total length of hospital stay, costs, and mortality were significantly higher among patients with CCI. Mechanical ventilation, sepsis, Glasgow score < 15, inadequate calorie intake, and higher body mass index were independent predictors for cci in the multivariate logistic regression model. CONCLUSIONS: CCI affects a distinctive population in intensive care units with higher mortality, costs, and prolonged hospitalization. Factors identifiable at the time of admission or during the first week in the intensive care unit can be used to predict CCI.

  12. Surveillance Monitoring Management for General Care Units: Strategy, Design, and Implementation.

    Science.gov (United States)

    McGrath, Susan P; Taenzer, Andreas H; Karon, Nancy; Blike, George

    2016-07-01

    The growing number of monitoring devices, combined with suboptimal patient monitoring and alarm management strategies, has increased "alarm fatigue," which have led to serious consequences. Most reported alarm man- agement approaches have focused on the critical care setting. Since 2007 Dartmouth-Hitchcock (Lebanon, New Hamp- shire) has developed a generalizable and effective design, implementation, and performance evaluation approach to alarm systems for continuous monitoring in general care settings (that is, patient surveillance monitoring). In late 2007, a patient surveillance monitoring system was piloted on the basis of a structured design and implementation approach in a 36-bed orthopedics unit. Beginning in early 2009, it was expanded to cover more than 200 inpatient beds in all medicine and surgical units, except for psychiatry and labor and delivery. Improvements in clinical outcomes (reduction of unplanned transfers by 50% and reduction of rescue events by more than 60% in 2008) and approximately two alarms per patient per 12-hour nursing shift in the original pilot unit have been sustained across most D-H general care units in spite of increasing patient acuity and unit occupancy. Sample analysis of pager notifications indicates that more than 85% of all alarm conditions are resolved within 30 seconds and that more than 99% are resolved before escalation is triggered. The D-H surveillance monitoring system employs several important, generalizable features to manage alarms in a general care setting: alarm delays, static thresholds set appropriately for the prevalence of events in this setting, directed alarm annunciation, and policy-driven customization of thresholds to allow clinicians to respond to needs of individual patients. The systematic approach to design, implementation, and performance management has been key to the success of the system.

  13. Briefing on meetings at & reports by the 65th & 66th United Nations General Assembly

    OpenAIRE

    Rojas Gregorio, José Ignacio

    2011-01-01

    Briefing on meetings at & reports by the 65th & 66th United Nations General Assembly No relevant differences are observed or identified after perusal of the space-related resolutions and documents issued by the UN System between 2010 and 2011. The most remarkable statements remain virtually unchanged in this time period. For instance, the UN GA recognizes the common interest of all mankind in the exploration and use of outer space for peaceful purposes, and reaffirms that these shall be ca...

  14. Analysis of referrals received by a psychiatric unit in a general hospital Part 2

    Directory of Open Access Journals (Sweden)

    VJ Ehlers

    2002-01-01

    Full Text Available The study sought to analyse the referrals received by a psychiatric unit in a general hospital in the Western Cape by studying the referral letters and the referral responses.

    Opsomming
    Hierdie navorsing het gepoog om verwysings te ontleed wat deur 'n psigiatriese eenheid in 'n algemene hospitaal in die Wes Kaap ontvang is. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.

  15. Setting up a Paediatric Rapid Access Outpatient Unit: Views of general practice teams

    Directory of Open Access Journals (Sweden)

    Pink Jim

    2008-09-01

    Full Text Available Abstract Background Rapid Access Outpatient Units (RAOUs have been suggested as an alternative to hospital inpatient units for the management of some acutely unwell children. These units can provide ambulatory care, delivered close to home, and may prevent unnecessary hospital admission. There are no qualitative data on the views of primary care practitioners regarding these types of facilities. The aim of the study was to explore the opinions of primary care practitioners regarding a newly established RAOU. Methods The RAOU was established locally at a district general hospital when inpatient beds were closed and moved to an inpatient centre, based six miles away at the tertiary teaching hospital. Qualitative, practice based group interviews with primary care practitioners (general practitioners (GPs, nurse practitioners and practice nurses on their experiences of the RAOU. The data collection consisted of three practice based interviews with 14 participants. The interviews were recorded and transcribed verbatim. Thematic content analysis was used to evaluate the data. Results There was positive feedback regarding ease of telephone access for referral, location, and the value of a service staffed by senior doctors where children could be observed, investigated and discharged quickly. There was confusion regarding the referral criteria for the assessment unit and where to send certain children. A majority of the practitioners felt the utility of the RAOU was restricted by its opening hours. Most participants felt they lacked sufficient information regarding the remit and facilities of the unit and this led to some uneasiness regarding safety and long term sustainability. Conclusion Practitioners considered that the RAOU offered a rapid senior opinion, flexible short term observation, quick access to investigations and was more convenient for patients. There were concerns regarding opening hours, safety of patients and lack of information about

  16. Generalized Thermodynamics of Phase Equilibria in Scalar Active Matter

    OpenAIRE

    Solon, Alexandre P.; Stenhammar, Joakim; Cates, Michael E.; Kafri, Yariv; Tailleur, Julien

    2016-01-01

    Motility-induced phase separation (MIPS) arises generically in fluids of self-propelled particles when interactions lead to a kinetic slowdown at high density. Starting from a continuum description of diffusive scalar active matter, we give a general prescription for phase equilibria that amounts, at a hydrodynamics scale, to extremalizing a generalized free energy. We illustrate our approach on two well known models: self-propelled particles interacting either through a density-dependent pro...

  17. Environmental activism and dynamics of unit-based pricing systems

    Energy Technology Data Exchange (ETDEWEB)

    Dijkgraaf, Elbert [SEOR-ECRi and Erasmus School of Economics, Erasmus University Rotterdam, Room H 7-25, P.O. Box 1738, 3000 DR Rotterdam (Netherlands); Gradus, Raymond [Vrije Universiteit Amsterdam and ECRi, De Boelelaan 1105, Room 1E-66, 1081 HV Amsterdam (Netherlands)

    2009-01-15

    It is well-known that unit-based pricing systems have a significant effect on the quantity of collected waste. Part of this effect may, however, result from a selection bias or environmental activism effect. Based on a pooled cross-section for the Netherlands for 1998-2005 we show that despite the correction for environmental activism the effect of the weight and bag unit-based pricing system on the quantity of waste is sizeable. Moreover, this environmental activism effect is decreasing over time, so that the most environmental friendly municipalities implement unit-based pricing systems at first. In addition, we show that the volume effects of the different unit-based pricing systems are rather stable over time. Although we find some evidence for a learning effect, nearly no evidence is found for an awareness erosion effect. This means at least that the effect of unit-based pricing does not decrease over time, which is reassuring from an environmental point of view. Pricing waste helps. (author)

  18. 43 CFR 44.57 - Can a unit of general local government appeal a rejection of a protest?

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Can a unit of general local government... the Interior FINANCIAL ASSISTANCE, LOCAL GOVERNMENTS State and Local Governments' Responsibilities After the Department Distributes Payments § 44.57 Can a unit of general local government appeal...

  19. 43 CFR 44.55 - Can a unit of general local government protest the results of payment computations?

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Can a unit of general local government... Secretary of the Interior FINANCIAL ASSISTANCE, LOCAL GOVERNMENTS State and Local Governments' Responsibilities After the Department Distributes Payments § 44.55 Can a unit of general local government...

  20. Generalized synchronization of hyperchaos and chaos using active backstepping design

    Institute of Scientific and Technical Information of China (English)

    张浩; 马西奎; 杨宇; 徐翠东

    2005-01-01

    A novel active backstepping control method is presented for synchronizing two identical Rossler hyperchaotic systems with each other, and extended to achieve the generalized synchronization of the Chua chaotic system with the Rossler hyperchaotic system. It is a systematic design approach and consists of a recursive procedure interlacing the choice of a Lyapunov function with the design of active control. In particular, this technique gives flexibility in constructing a control law. Numerical experiments verify the feasibility and effectiveness of the proposed control technique.

  1. Strategic Priorities for Physical Activity Surveillance in the United States.

    Science.gov (United States)

    Fulton, Janet E; Carlson, Susan A; Ainsworth, Barbara E; Berrigan, David; Carlson, Cynthia; Dorn, Joan M; Heath, Gregory W; Kohl, Harold W; Lee, I-Min; Lee, Sarah M; Másse, Louise C; Morrow, James R; Gabriel, Kelley Pettee; Pivarnik, James M; Pronk, Nicolaas P; Rodgers, Anne B; Saelens, Brian E; Sallis, James F; Troiano, Richard P; Tudor-Locke, Catrine; Wendel, Arthur

    2016-10-01

    Develop strategic priorities to guide future physical activity surveillance in the United States. The Centers for Disease Control and Prevention and the American College of Sports Medicine convened a scientific roundtable of physical activity and measurement experts. Participants summarized the current state of aerobic physical activity surveillance for adults, focusing on practice and research needs in three areas: 1) behavior, 2) human movement, and 3) community supports. Needs and challenges for each area were identified. At the conclusion of the meeting, experts identified one overarching strategy and five strategic priorities to guide future surveillance. The identified overarching strategy was to develop a national plan for physical activity surveillance similar to the U.S. National Physical Activity Plan for promotion. The purpose of the plan would be to enhance coordination and collaboration within and between sectors, such as transportation and public health, and to address specific strategic priorities identified at the roundtable. These strategic priorities were used 1) to identify and prioritize physical activity constructs; 2) to assess the psychometric properties of instruments for physical activity surveillance; 3) to provide training and technical assistance for those collecting, analyzing, or interpreting surveillance data; 4) to explore accessing data from alternative sources; and 5) to improve communication, translation, and dissemination about estimates of physical activity from surveillance systems. This roundtable provided strategic priorities for physical activity surveillance in the United States. A first step is to develop a national plan for physical activity surveillance that would provide an operating framework from which to execute these priorities.

  2. Contribution of the outpatient surgery unit ITO the general surgery department of a district hospital.

    Science.gov (United States)

    Carrasco; Flores; Aguayo; de Andres B; Moreno Egea A; Cartagena; De Vicente JP; Martin

    2000-07-01

    Introduction: The creation of Outpatient Surgery (OPS) units to combine the quality of medical attention and rationalize costs allows for greater efficiency in the use of resources. Aim: To report our series of patients undergoing surgery at the OPS units integrated into our Hospital (Type II): Patients and method: Between May 1994 and March 1998, 832 outpatients, of a total of 5230, underwent surgery at our General Surgery Unit. The criteria for exclusion from the programme depended on the patient and the enviroment or resulted from the operation itself. Results: Mean patient age was 47.5 years; there were 420 males and 412 females. Surgery was performed for 229 inguinofemoral hernias, 47 umbilical-epigastric hernias, nine incisional hernias, 193 pilonidal sinuses, 156 mammary nodules, 65 varicose veins, 64 arteriovenous fistulae and 69 proctology operations. The most common anesthesia techniques performed were rachianesthesia and local anesthesia. Eight point seven percent of the patients required admission (OPS failure), the most frequent causes being excessive pain, orthostatic-syncopal hypotension, nausea and vomiting and urine retention. There was no morbidity or mortality. Conclusion: OPS is a highly efficient procedure for resolving the most common pathologies in General Surgery. The anesthesia technique was an important factor in the rate of failure.

  3. How do general practitioners in Denmark promote physical activity?

    DEFF Research Database (Denmark)

    Jørgensen, Tanja K; Nordentoft, Merete; Krogh, Jesper

    2012-01-01

    The primary objective of this study was to quantify the frequency of advice given on type, frequency, duration, and intensity of exercise during physical activity (PA) promoting sessions by general practitioners. Second, to find GP characteristics associated with high quality of PA counselling....

  4. Solar energy education. Renewable energy activities for general science

    Energy Technology Data Exchange (ETDEWEB)

    1985-01-01

    Renewable energy topics are integrated with the study of general science. The literature is provided in the form of a teaching manual and includes such topics as passive solar homes, siting a home for solar energy, and wind power for the home. Other energy topics are explored through library research activities. (BCS)

  5. Generalized boundaries of the National Water-Quality Assessment (NAWQA) Study-Unit Investigations in the conterminous United States 2001-2012

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This is a GENERALIZED version of the boundaries and codes used for the U.S. Geological Survey's National Water-Quality Assessment (NAWQA) Program Study-Unit...

  6. Generalized boundaries of the National Water-Quality Assessment (NAWQA) Study-Unit Investigations in the conterminous United States 1991-2001

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This is a GENERALIZED version of the boundaries and codes used for the U.S. Geological Survey's National Water-Quality Assessment (NAWQA) Program Study-Unit...

  7. The impact of a surgical assessment unit on numbers of general surgery outliers.

    Science.gov (United States)

    Jacobson, Alexandra; Poole, Garth; Hill, Andrew G; Biggar, Magdalena

    2016-12-02

    Patient care and efficiency outcomes are improved if acute patients admitted to non-specialty (outlier) wards are minimised.1 Assessment units may help to reduce numbers of outlier patients.2 A surgical assessment unit (SAU) was recently established at Middlemore Hospital. We aimed to determine the impact of its introduction on numbers of general surgery outliers on post-acute ward rounds. A 10-bed SAU was introduced in July 2015, coinciding with the closure of 20 beds on the general surgical wards. The numbers and locations of patients on post-acute ward rounds before and after the establishment of the SAU were compared. A student two-tailed t-test was used for statistical comparisons, with poutlier wards after the introduction of the SAU (mean 1.7 before vs 0.8 after, p=0.04). Despite a net reduction in general surgery beds and no change in the overall number of post-acute patients, the establishment of a SAU was associated with a reduction in outliers.

  8. Comparison of maternal anxiety scores in pediatric intensive care unit and general ward parents

    Directory of Open Access Journals (Sweden)

    Lie Affendi Kartikahadi

    2012-02-01

    Full Text Available Background Hospitalization of a child is known to be a dreadful and stressful situation for parents. One study reported that admitting a child to a general ward caused mild anxiety to mothers, while admitting a child to the pediatric intensive care unit (PICU caused moderate anxiety to mothers. Objective To compare Hamilton anxiety scores of mothers whose children were admitted to the PICU to those of mothers whose children were admitted to the general ward. Methods A cross-sectional study was done on mothers of children aged 1 month-12 years. Children were admitted to either the intensive care unit or the general ward from October 2010-January 2011. All subjects were assessed by Hamilton anxiety scores and questioned for risk factors and other causes of maternal anxiety. Consecutive sampling was used to allocate the subjects. Differences were considered statistically significant for P < 0.05. Results Of the 72 subjects, the median Hamilton anxiety score in mothers of children admitted to the PICU was 20.5 (interquartile range 14-29.75, higher than that of mothers of children admitted to the general ward (14, interquartile range 9-16.75. Mann-Whitney U test revealed a statistically significant difference in scores between the two groups (P = 0.001. Ancova multivariate analysis showed the admission location to be the only significant relationship to Hamilton anxiety score (P = 0.0001. Conclusion Hamilton anxiety scores were higher for mothers of children admitted to the PICU than that of mothers with children admitted to the general ward. [Paediatr Indones.2012;52:95-8].

  9. Quality of stroke care at an Irish Regional General Hospital and Stroke Rehabilitation Unit.

    LENUS (Irish Health Repository)

    Walsh, T

    2012-01-31

    BACKGROUND: Robust international data support the effectiveness of stroke unit (SU) care. Despite this, most stroke care in Ireland are provided outside of this setting. Limited data currently exist on the quality of care provided. AIM: The aim of this study is to examine the quality of care for patients with stroke in two care settings-Regional General Hospital (RGH) and Stroke Rehabilitation Unit (SRU). METHODS: A retrospective analysis of the stroke records of consecutive patients admitted to the SRU between May-November 2002 and April-November 2004 was performed applying the UK National Sentinel Audit of Stroke (NSAS) tool. RESULTS: The results of the study reveal that while SRU processes of care was 74% compliant with standards; compliance with stroke service organisational standards was only 15 and 43% in the RGH and SRU, respectively. CONCLUSION: The quality of stroke care in our area is deficient. Comprehensive reorganisation of stroke services is imperative.

  10. Special Inspector General for Afghanistan Reconstruction Quarterly Report to the United States Congress

    Science.gov (United States)

    2014-10-30

    terminated the contract for convenience . State also funded three capital-improvement projects—a potable-water tower, a commercial power upgrade, and...Million 37 SIGAR OVERSIGHT ACTIVITIES REPORT TO THE UNITED STATES CONGRESS I OCTOBER 30, 2014 convenience . INL paid AWCC $18.5 million of the $20.2...Abduzaziz, the owner of Aziz Restaurant and a bazaar, who was allegedly engaging in various criminal schemes on BAF, including vehicle thefts. The TCN

  11. Are Regional Organizations the 'Parties' in the United Nations General Assembly? Comments on a Misconception

    DEFF Research Database (Denmark)

    Burmester, Nicolas; Jankowski, Michael

    In the field of international relations, regional organizations (ROs) are not only assumed to play an important role in the regional context, but also on the international level. A growing number of studies analyze ROs’ voting behavior in the United Nations General Assembly (UNGA) in a similar way...... to the analyses of parties in national parliaments. In this paper, we reflect on the question whether ROs can be treated as ‘political party’-like entities. First, based on literature on political parties and legislative voting, we develop two criteria to evaluate ROs in the UNGA. Second, we analyze UNGA voting...

  12. The Slavery in Circassia and the United States (1850–1860-ies years: General and Special

    Directory of Open Access Journals (Sweden)

    Mikhal Smigel

    2016-12-01

    Full Text Available The article provides a comparative analysis of slavery in Circassia and in the territory of the slave South in the United States in 1850–1860-ies years in the context of the fight against the slave trade and slavery in the world. The article discusses the Russian-American general trends for the prohibition of slavery and the slave trade. Among the materials are Russian and foreign archival sources, documents of personal origin (memoirs, diaries of travelers as well as scientific research. The methodological basis of historical-comparative study are the principles of objectivity and historicism, suggesting an unbiased approach to the analysis of the studied problems, a critical attitude to the sources, making judgments as a result of the analysis of a set of facts, and displays the slave of phenomena in the development and the context of the historical situation. In conclusion, the authors note that slavery and the slave position in the United States and the Circassia had their differences in 1850–1860-ies. Such differences included the inability of the transition to the United States from the status of a slave in the state of the dependent peasant, which was the norm in Circassia. In the United States the slaves were brought from outside, while in Circassia the slavery occurred in the region, mainly by trapping. At the root of discrimination in the United States was the racial principle, in Circassia this is based on the religious principle. The position of slaves had their similarities. A slave was powerless property of his master, there were certain unwritten rules governing the relationship, slave owners were reluctant to bring slaves to the extreme and etc. The important similarity between the US and Circassia was the presence of their territories with a strong slave system, where slaves constituted more than 30 % of the population. In the US, it was the territory of the slave-holding South, and in Circassia – the slaveholding Ubykhia.

  13. Case mix, outcome and activity for patients with severe acute kidney injury during the first 24 hours after admission to an adult, general critical care unit: application of predictive models from a secondary analysis of the ICNARC Case Mix Programme database.

    Science.gov (United States)

    Kolhe, Nitin V; Stevens, Paul E; Crowe, Alex V; Lipkin, Graham W; Harrison, David A

    2008-01-01

    This study pools data from the UK Intensive Care National Audit and Research Center (ICNARC) Case Mix Programme (CMP) to evaluate the case mix, outcome and activity for 17,326 patients with severe acute kidney injury (AKI) occurring during the first 24 hours of admission to intensive care units (ICU). Severe AKI admissions (defined as serum creatinine >/=300 mumol/l and/or urea >/=40 mmol/l during the first 24 hours) were extracted from the ICNARC CMP database of 276,326 admissions to UK ICUs from 1995 to 2004. Subgroups of oliguric and nonoliguric AKI were identified by daily urine output. Data on surgical status, survival and length of stay were also collected. Severity of illness scores and mortality prediction models were compared (UK Acute Physiology and Chronic Health Evaluation [APACHE] II, Stuivenberg Hospital Acute Renal Failure [SHARF] T0, SHARF II0 and the Mehta model). Severe AKI occurred in 17,326 out of 276,731 admissions (6.3%). The source of admission was nonsurgical in 83.7%. Sepsis was present in 47.3% and AKI was nonoliguric in 63.9% of cases. Admission to ICU with severe AKI accounted for 9.3% of all ICU bed-days. Oliguric AKI was associated with longer length of stay for survivors and shorter length of stay for nonsurvivors compared with nonoliguric AKI. Oliguric AKI was associated with significantly greater ICU and hospital mortality (55.8% and 77.3%, respectively) compared with nonoliguric AKI (33.4% and 49.3%, respectively). Surgery during the 1 week before admission or during the first week in the CMP unit was associated with decreased odds of mortality. UK APACHE II and the Mehta scores under-predicted the number of deaths, whereas SHARF T0 and SHARF II0 over-predicted the number of deaths. Severe AKI accounts for over 9% of all bed-days in adult, general ICUs, representing a considerable drain on resources. Although nonoliguric AKI continues to confer a survival benefit, overall survival from AKI in the ICU and survival to leave hospital

  14. [Analysis of cost and efficiency of a medical nursing unit using time-driven activity-based costing].

    Science.gov (United States)

    Lim, Ji Young; Kim, Mi Ja; Park, Chang Gi

    2011-08-01

    Time-driven activity-based costing was applied to analyze the nursing activity cost and efficiency of a medical unit. Data were collected at a medical unit of a general hospital. Nursing activities were measured using a nursing activities inventory and classified as 6 domains using Easley-Storfjell Instrument. Descriptive statistics were used to identify general characteristics of the unit, nursing activities and activity time, and stochastic frontier model was adopted to estimate true activity time. The average efficiency of the medical unit using theoretical resource capacity was 77%, however the efficiency using practical resource capacity was 96%. According to these results, the portion of non-added value time was estimated 23% and 4% each. The sums of total nursing activity costs were estimated 109,860,977 won in traditional activity-based costing and 84,427,126 won in time-driven activity-based costing. The difference in the two cost calculating methods was 25,433,851 won. These results indicate that the time-driven activity-based costing provides useful and more realistic information about the efficiency of unit operation compared to traditional activity-based costing. So time-driven activity-based costing is recommended as a performance evaluation framework for nursing departments based on cost management.

  15. The United Kingdom 2009 Swine Flu Outbreak As Recorded in Real Time by General Practitioners

    Directory of Open Access Journals (Sweden)

    Hershel Jick

    2011-01-01

    Full Text Available Background. Initially the course of the 2009 swine flu pandemic was uncertain and impossible to predict with any confidence. An effective prospective data resource exists in the United Kingdom (UK that could have been utilized to describe the scope and extent of the swine flu outbreak as it unfolded. We describe the 2009 swine flu outbreak in the UK as recorded daily by general practitioners and the potential use of this database for real-time tracking of flu outbreaks. Methods. Using the General Practice Research Database, a real-time general practice, electronic database, we estimated influenza incidence from July 1998 to September 2009 according to age, region, and calendar time. Results. From 1998 to2008, influenza outbreaks regularly occurred yearly from October to March, but did not typically occur from April to September until the swine flu outbreak began in April 2009. The weekly incidence rose gradually, peaking at the end of July, and the outbreak had largely dissipated by early September. Conclusions. The UK swine flu outbreak, recorded in real time by a large group of general practitioners, was mild and limited in time. Simultaneous online access seemed feasible and could have provided additional clinical-based evidence at an early planning stage of the outbreak.

  16. The General Urban Plan of Casimcea territorial administrative unit, map of natural and anthropogenic risks

    Directory of Open Access Journals (Sweden)

    Sorin BĂNICĂ

    2013-08-01

    Full Text Available The General Urban Plan represents the legal ground for any development action proposed. After endorsement and approval as required by law, GUP is act of authority of local government for the area in which it applies. The aim is to establish priorities regulations applied in land use planning and construction of structures. In terms of geographical location, the administrative territory of Casimcea, Tulcea county, falls in the central Northwest Plateau Casimcei. This is the second unit of the Central Dobrogea Plateau. Geographical location in southeastern Romania, climatic and relief conditions and anthropogenic pressure, expose the village administrative territorial unit Casimcea, permanent susceptibility to produce natural and antropogenical risks. In this context, we identified the following categories of natural and anthropogenic risks: i natural risk phenomena (earthquakes, strong winds, heavy rains, floods caused by overflowing or precipitation, erosion of river banks and torrents, gravitational processes, rain droplet erosion and surface soil erosion; and ii anthropogenic risk phenomena (overgrazing, chemicals use in agriculture, road transport infrastructure and electricity, wind turbines for electricity production, waste deposits, agro-zootechnical complexs, and human cemeteries. Extending their surface was materialized by creating a map of natural and anthropogenic risk on Casimcea territorial administrative unit, explaining the share of potentially affected areas as territorial balance

  17. Smart panel with active damping units. Implementation of decentralized control.

    Science.gov (United States)

    Díaz, Cristóbal González; Paulitsch, Christoph; Gardonio, Paolo

    2008-08-01

    This paper contains the second part of a study on a smart panel with five decentralized velocity feedback control units using proof mass electrodynamic actuators [Gonzalez Diaz et al., J. Acoust. Soc. Am. 124, 886 (2008)]. The implementation of five decentralized control loops is analyzed, both theoretically and experimentally. The stability properties of the five decentralized control units have been assessed with the generalized Nyquist criterion by plotting the loci of the eigenvalues of the fully populated matrix of frequency response functions between the five error signals and five input signals to the amplifiers driving the actuators. The control performance properties have been assessed in terms of the spatially averaged response of the panel measured with a scanning laser vibrometer and the total sound power radiated measured in an anechoic room. The two analyses have shown that reductions of up to 10 dB in both vibration response and sound radiation are measured at low audio frequencies, below about 250 Hz.

  18. Generalized event knowledge activation during online sentence comprehension

    Science.gov (United States)

    Metusalem, Ross; Kutas, Marta; Urbach, Thomas P.; Hare, Mary; McRae, Ken; Elman, Jeffrey L.

    2012-01-01

    Recent research has demonstrated that knowledge of real-world eventsplays an important role inguiding online language comprehension. The present study addresses the scope of event knowledge activation during the course of comprehension, specifically investigating whether activation is limited to those knowledge elements that align with the local linguistic context.The present study addresses this issue by analyzing event-related brain potentials (ERPs) recorded as participants read brief scenariosdescribing typical real-world events. Experiment 1 demonstratesthat a contextually anomalous word elicits a reduced N400 if it is generally related to the described event, even when controlling for the degree of association of this word with individual words in the preceding context and with the expected continuation. Experiment 2 shows that this effect disappears when the discourse context is removed.These findings demonstrate that during the course of incremental comprehension, comprehenders activate general knowledge about the described event, even at points at which this knowledge would constitute an anomalous continuation of the linguistic stream. Generalized event knowledge activationcontributes to mental representations of described events, is immediately available to influence language processing, and likely drives linguistic expectancy generation. PMID:22711976

  19. Ute Unit: Study Guide and Follow Up Activities.

    Science.gov (United States)

    North Conejos School District, Capulin, CO.

    The study guide and follow-up activities were designed primarily to give students a feeling of Ute life in the San Luis Valley in Colorado. The unit begins with six Southern Ute stories about the wolf and coyote, the race between the skunk and the coyote, the frog and the eagle, why the frog croaks, the bear (Que Ye Qat), and the two Indian…

  20. Zero loss magnetic metamaterials using powered active unit cells.

    Science.gov (United States)

    Yuan, Yu; Popa, Bogdan-Ioan; Cummer, Steven A

    2009-08-31

    We report the design and experimental measurement of a powered active magnetic metamaterial with tunable permeability. The unit cell is based on the combination of an embedded radiofrequency amplifier and a tunable phase shifter, which together control the response of the medium. The measurements show that a negative permeability metamaterial with zero loss or even gain can be achieved through an array of such metamaterial cells. This kind of active metamaterial can find use in applications that are performance limited due to material losses.

  1. Geothermal exploitation activity by the United Nations in Ethiopia

    Energy Technology Data Exchange (ETDEWEB)

    Nakamura, H. (Geological Survey of Japan)

    1971-01-01

    The Rift Valley in Ethiopia was investigated for geothermal exploitation by the United Nations because it has Quaternary volcanoes which often indicate possible geothermal power generation. Preparations for the project are still being made, and the chemical analysis of hot springs is being conducted. The Rift Valley has high temperature springs and potential mineral deposits. The Danakil basin in Ethiopia which is included in the Northern Afar, has several active volcanoes made up of basalt deposits and has active hot springs. The East Africa Rift Valley, the Red Sea Rift Valley, and the Afar area are also areas suitable for investigation. Seven maps are included.

  2. Assembling optically active and nonactive metamaterials with chiral units

    Directory of Open Access Journals (Sweden)

    Xiang Xiong

    2012-12-01

    Full Text Available Metamaterials constructed with chiral units can be either optically active or nonactive depending on the spatial configuration of the building blocks. For a class of chiral units, their effective induced electric and magnetic dipoles, which originate from the induced surface electric current upon illumination of incident light, can be collinear at the resonant frequency. This feature provides significant advantage in designing metamaterials. In this paper we concentrate on several examples. In one scenario, chiral units with opposite chiralities are used to construct the optically nonactive metamaterial structure. It turns out that with linearly polarized incident light, the pure electric or magnetic resonance (and accordingly negative permittivity or negative permeability can be selectively realized by tuning the polarization of incident light for 90°. Alternatively, units with the same chirality can be assembled as a chiral metamaterial by taking the advantage of the collinear induced electric and magnetic dipoles. It follows that for the circularly polarized incident light, negative refractive index can be realized. These examples demonstrate the unique approach to achieve certain optical properties by assembling chiral building blocks, which could be enlightening in designing metamaterials.

  3. Stress, coping, and general health of nurses who work in units that assist AIDS-carriers and patients with

    OpenAIRE

    2008-01-01

    Based on Lazarus and Folkman’s theory about stress and coping, this research aimed at answering questions related to how nurses, who work in two specialized units of a general hospital, evaluate their working environment, their health and how they manage with stressing situations. In the unit of infectious diseases, the nurses’ evaluation of their working environment did not surpass the limits of what is considered as acceptable. In the unit of hematological alterations, the results showed hi...

  4. General Purpose Graphics Processing Unit Based High-Rate Rice Decompression and Reed-Solomon Decoding.

    Energy Technology Data Exchange (ETDEWEB)

    Loughry, Thomas A.

    2015-02-01

    As the volume of data acquired by space-based sensors increases, mission data compression/decompression and forward error correction code processing performance must likewise scale. This competency development effort was explored using the General Purpose Graphics Processing Unit (GPGPU) to accomplish high-rate Rice Decompression and high-rate Reed-Solomon (RS) decoding at the satellite mission ground station. Each algorithm was implemented and benchmarked on a single GPGPU. Distributed processing across one to four GPGPUs was also investigated. The results show that the GPGPU has considerable potential for performing satellite communication Data Signal Processing, with three times or better performance improvements and up to ten times reduction in cost over custom hardware, at least in the case of Rice Decompression and Reed-Solomon Decoding.

  5. General Purpose Graphics Processing Unit Based High-Rate Rice Decompression and Reed-Solomon Decoding

    Energy Technology Data Exchange (ETDEWEB)

    Loughry, Thomas A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-02-01

    As the volume of data acquired by space-based sensors increases, mission data compression/decompression and forward error correction code processing performance must likewise scale. This competency development effort was explored using the General Purpose Graphics Processing Unit (GPGPU) to accomplish high-rate Rice Decompression and high-rate Reed-Solomon (RS) decoding at the satellite mission ground station. Each algorithm was implemented and benchmarked on a single GPGPU. Distributed processing across one to four GPGPUs was also investigated. The results show that the GPGPU has considerable potential for performing satellite communication Data Signal Processing, with three times or better performance improvements and up to ten times reduction in cost over custom hardware, at least in the case of Rice Decompression and Reed-Solomon Decoding.

  6. Review of paediatric cardiology services in district general hospitals in the United Kingdom.

    Science.gov (United States)

    Andrews, Hannah; Singh, Yogen

    2016-03-01

    Following the Safe and Sustainable review of Paediatric Services in 2012/2013, National Health Service England recommended that local paediatric cardiology services should be provided by specially trained paediatricians with expertise in cardiology in all non-specialist hospitals. To understand the variation in local paediatric cardiology services provided across district general hospitals in the United Kingdom. An internet-based questionnaire was sent out via the Paediatrician with Expertise in Cardiology Special Interest Group and the Neonatologists with Interest in Cardiology and Haemodynamics contact databases and the National Health Service directory. Non-responders were followed-up via telephone. The response rate was 80% (141 of 177 hospitals), and paediatricians with expertise in cardiology were available in 68% of those. Local cardiology clinics led by paediatricians with expertise in cardiology were provided in 96 hospitals (68%), whereas specialist outreach clinics were held in 123 centres (87%). A total of 11 hospitals provided neither specialist outreach clinics nor any local cardiology clinics led by paediatricians with expertise in cardiology. Paediatric echocardiography services were provided in 83% of the hospitals, 12-lead electrocardiogram in 96%, Holter electrocardiogram in 91%, and exercise testing in only 47% of the responding hospitals. Telemedicine facilities were established in only 52% of the centres, where sharing echocardiogram images via picture archiving and communication system was used most commonly. There has been a substantial increase in the availability of paediatricians with expertise in cardiology since 2008. Most of the hospitals are well-supported by specialist cardiology centres via outreach clinics; however, there remains significant variation in the local paediatric cardiology services provided across district general hospitals in the United Kingdom.

  7. Hippocampal unit activity during classical aversive and appetitive conditioning.

    Science.gov (United States)

    Segal, M; Disterhoft, J F; Olds, J

    1972-02-18

    Rats were trained with a tone being followed by either food or electric shock, on alternate days. Unit activity during application of the conditioned stimulus was recorded from the dorsal hippocampus. The results indicate differentiation of the hippocampal system. Dentate units respond by augmentation to a conditioned stimulus which leads to food and by inhibition to the same stimulus when it precedes electric shock. The hippocampus proper responds by augmentation in both situations. The intensity of the hippocampal response to the conditioned stimulus on the first day of training is higher if the unconditioned stimulus is food than if it is electric shock. These data cast light on the functions of the dorsal dentate-hippocampal connections and the hippocampus proper during aversive and appetitive conditioning.

  8. The United Nations Human Space Technology Initiative (HSTI): Science Activities

    CERN Document Server

    Niu, A; Haubold, H J; Doi, T

    2012-01-01

    The United Nations Human Space Technology Initiative (HSTI) aims at promoting international cooperation in human spaceflight and space exploration-related activities; creating awareness among countries on the benefits of utilizing human space technology and its applications; and building capacity in microgravity education and research. HSTI has been conducting various scientific activities to promote microgravity education and research. The primary science activity is called 'Zero-gravity Instrument Distribution Project', in which one-axis clinostats will be distributed worldwide. The distribution project will provide unique opportunities for students and researchers to observe the growth of indigenous plants in their countries in a simulated microgravity condition and is expected to create a huge dataset of plant species with their responses to gravity.

  9. Generalized anxiety modulates frontal and limbic activation in major depression

    Directory of Open Access Journals (Sweden)

    Schlund Michael W

    2012-02-01

    Full Text Available Abstract Background Anxiety is relatively common in depression and capable of modifying the severity and course of depression. Yet our understanding of how anxiety modulates frontal and limbic activation in depression is limited. Methods We used functional magnetic resonance imaging and two emotional information processing tasks to examine frontal and limbic activation in ten patients with major depression and comorbid with preceding generalized anxiety (MDD/GAD and ten non-depressed controls. Results Consistent with prior studies on depression, MDD/GAD patients showed hypoactivation in medial and middle frontal regions, as well as in the anterior cingulate, cingulate and insula. However, heightened anxiety in MDD/GAD patients was associated with increased activation in middle frontal regions and the insula and the effects varied with the type of emotional information presented. Conclusions Our findings highlight frontal and limbic hypoactivation in patients with depression and comorbid anxiety and indicate that anxiety level may modulate frontal and limbic activation depending upon the emotional context. One implication of this finding is that divergent findings reported in the imaging literature on depression could reflect modulation of activation by anxiety level in response to different types of emotional information.

  10. Twenty years of electroconvulsive therapy in a psychiatric unit at a university general hospital

    Directory of Open Access Journals (Sweden)

    Amilton dos Santos Jr.

    2013-01-01

    Full Text Available Objective: To describe the sociodemographic and clinical profile of patients who underwent electroconvulsive therapy (ECT at a university general hospital. Method: In this retrospective study, records from all patients undergoing ECT between January 1988 and January 2008 at the psychiatric unit of the general hospital of Universidade Estadual de Campinas (UNICAMP were reviewed. Telephone contact was made with patients/relatives to collect follow-up data. Results: A total of 200 charts were reviewed. The majority of patients were women, with a mean age of 39 years, and history of psychiatric hospitalization. The main indications for ECT were depression and catatonia. Complications were observed in less than half of the cases, and most were temporary and not severe. There was a good psychiatric outcome for 89.7% of the patients, especially for catatonic patients (100%, p = 0.02. Thirty-four percent of the cases were later contacted by telephone calls, at a mean of 8.5 years between the procedure and the contact. Among these, three (1.5% reported persistent memory disorders and 73% considered ECT a good treatment. Conclusion: ECT has been performed according to international guidelines. In the vast majority of cases, undesirable effects were temporary and not severe. Response to ECT was positive in most cases, particularly in catatonic patients.

  11. A general method for determining secondary active transporter substrate stoichiometry.

    Science.gov (United States)

    Fitzgerald, Gabriel A; Mulligan, Christopher; Mindell, Joseph A

    2017-01-25

    The number of ions required to drive substrate transport through a secondary active transporter determines the protein's ability to create a substrate gradient, a feature essential to its physiological function, and places fundamental constraints on the transporter's mechanism. Stoichiometry is known for a wide array of mammalian transporters, but, due to a lack of readily available tools, not for most of the prokaryotic transporters for which high-resolution structures are available. Here, we describe a general method for using radiolabeled substrate flux assays to determine coupling stoichiometries of electrogenic secondary active transporters reconstituted in proteoliposomes by measuring transporter equilibrium potentials. We demonstrate the utility of this method by determining the coupling stoichiometry of VcINDY, a bacterial Na(+)-coupled succinate transporter, and further validate it by confirming the coupling stoichiometry of vSGLT, a bacterial sugar transporter. This robust thermodynamic method should be especially useful in probing the mechanisms of transporters with available structures.

  12. Emergent patterns from probabilistic generalizations of lateral activation and inhibition

    Science.gov (United States)

    Kabla, Alexandre

    2016-01-01

    The combination of laterally activating and inhibiting feedbacks is well known to spontaneously generate spatial organization. It was introduced by Gierer and Meinhardt as an extension of Turing's great insight that two reacting and diffusing chemicals can spontaneously drive spatial morphogenesis per se. In this study, we develop an accessible nonlinear and discrete probabilistic model to study simple generalizations of lateral activation and inhibition. By doing so, we identify a range of modes of morphogenesis beyond the familiar Turing-type modes; notably, beyond stripes, hexagonal nets, pores and labyrinths, we identify labyrinthine highways, Kagome lattices, gyrating labyrinths and multi-colour travelling waves and spirals. The results are discussed within the context of Turing's original motivating interest: the mechanisms which underpin the morphogenesis of living organisms. PMID:27170648

  13. 75 FR 62424 - New United Motor Manufacturing, Inc. Formerly a Joint Venture of General Motors Corporation and...

    Science.gov (United States)

    2010-10-08

    ... United Motor Manufacturing, Inc. Formerly a Joint Venture of General Motors Corporation and Toyota Motor Corporation Including On- Site Leased Workers From Corestaff, ABM Janitorial, Toyota Engineering and... Motor Manufacturing, Inc., formerly a joint venture of General Motors Corporation and Toyota...

  14. [Stress, coping, and general health of nurses working at a care unit for patients with AIDS and hematologic diseases].

    Science.gov (United States)

    Britto, Eliane da Silva; Carvalho, Ana Maria Pimenta

    2003-12-01

    Based on Lazarus and Folkman's theory about stress and coping, this research aimed at answering questions related to how nurses, who work in two specialized units of a general hospital, evaluate their working environment, their health and how they manage with stressing situations. In the unit of infectious diseases, the nurses' evaluation of their working environment did not surpass the limits of what is considered as acceptable. In the unit of hematological alterations, the results showed higher stress levels. In both units, the evaluation of their health was considered as satisfactory and the coping strategies were similar.

  15. Active microchannel fluid processing unit and method of making

    Science.gov (United States)

    Bennett, Wendy D [Kennewick, WA; Martin, Peter M [Kennewick, WA; Matson, Dean W [Kennewick, WA; Roberts, Gary L [West Richland, WA; Stewart, Donald C [Richland, WA; Tonkovich, Annalee Y [Pasco, WA; Zilka, Jennifer L [Pasco, WA; Schmitt, Stephen C [Dublin, OH; Werner, Timothy M [Columbus, OH

    2001-01-01

    The present invention is an active microchannel fluid processing unit and method of making, both relying on having (a) at least one inner thin sheet; (b) at least one outer thin sheet; (c) defining at least one first sub-assembly for performing at least one first unit operation by stacking a first of the at least one inner thin sheet in alternating contact with a first of the at least one outer thin sheet into a first stack and placing an end block on the at least one inner thin sheet, the at least one first sub-assembly having at least a first inlet and a first outlet; and (d) defining at least one second sub-assembly for performing at least one second unit operation either as a second flow path within the first stack or by stacking a second of the at least one inner thin sheet in alternating contact with second of the at least one outer thin sheet as a second stack, the at least one second sub-assembly having at least a second inlet and a second outlet.

  16. Recovering activity and illusion: the nephrology day care unit.

    Science.gov (United States)

    Remón Rodríguez, C; Quirós Ganga, P L; González-Outón, J; del Castillo Gámez, R; García Herrera, A L; Sánchez Márquez, M G

    2011-01-01

    Day Care Units are an alternative to hospital care that improves more efficiency. The Nephrology, by its technical characteristics, would be benefit greatly from further development of this care modality. The objectives of this study are to present the process we have developed the Nephrology Day Care Unit in the Puerto Real University Hospital (Cádiz, Spain). For this project we followed the Deming Management Method of Quality improvement, selecting opportunities, analyzing causes, select interventions, implement and monitor results. The intervention plan includes the following points: 1) Define the place of the Day Care Unit in the organization of our Clinical Department of Nephrology, 2) Define the Manual of organization, 3) Define the structural and equipment resources, 4) Define the Catalogue of services and procedures, 5) Standards of Care Processes. Protocols and Clinical Pathways; and 6) Information and Registration System. In the first 8 months we have been performed nearly 2000 procedures, which corresponds to an average of about 10 procedures per day, and essentially related to Hemodialysis in critical or acute patients, the Interventional Nephrology, the Clinical Nephrology and Peritoneal Dialysis. The development of the Nephrology Day Care Units can help to increase our autonomy, our presence in Hospitals, recover the progressive loss of clinical activity (diagnostic and therapeutic skills) in the past to the benefit of other Specialties. It also contributes to: Promote and develop the Diagnostic and Interventional Nephrology; improve the clinical management of patients with Primary Health Level, promote the Health Education and Investigation, collaborate in the Resources Management, and finally, to make more attractive and exciting our Specialty, both for nephrologists to training specialists.

  17. Incidence of cytomegalovirus infection among the general population and pregnant women in the United States

    Directory of Open Access Journals (Sweden)

    Dollard Sheila C

    2007-07-01

    Full Text Available Abstract Background Cytomegalovirus (CMV is a common opportunistic infection among HIV-infected individuals, a major source of serious complications among organ-transplant recipients, and a leading cause of hearing loss, vision loss, and mental retardation among congenitally infected children. Women infected for the first time during pregnancy are especially likely to transmit CMV to their fetuses. More children suffer serious disabilities caused by congenital CMV than by several better-known childhood maladies such as Down syndrome or fetal alcohol syndrome Methods Using CMV seroprevalence data from the nationally representative Third National Health and Nutrition Examination Survey, we estimated CMV incidence among the general United States population and among pregnant women. We employed catalytic models that used age-specific CMV seroprevalences as cumulative markers of past infections in order to derive estimates of three basic parameters: the force of infection, the basic reproductive rate, and the average age of infection. Our main focus was the force of infection, an instantaneous per capita rate of acquisition of infection that approximates the incidence of infection in the seronegative population. Results Among the United States population ages 12–49 the force of infection was 1.6 infections per 100 susceptible persons per year (95% confidence interval: 1.2, 2.4. The associated basic reproductive rate of 1.7 indicates that, on average, an infected person transmits CMV to nearly two susceptible people. The average age of CMV infection was 28.6 years. Force of infection was significantly higher among non-Hispanic Blacks (5.7 and Mexican Americans (5.1 than among non-Hispanic Whites (1.4. Force of infection was significantly higher in the low household income group (3.5 than in the middle (2.1 and upper (1.5 household income groups. Based on these CMV incidence estimates, approximately 27,000 new CMV infections occur among seronegative

  18. Envy-Free Pricing with General Supply Constraints for Unit Demand Consumers

    Institute of Scientific and Technical Information of China (English)

    Sungjin Im; Pin-Yan Lu; Ya-Jun Wang

    2012-01-01

    The envy-free pricing problem can be stated as finding a pricing and allocation scheme in which each consumer is allocated a set of items that maximize his/her utility under the pricing.The goal is to maximize seller revenue.We study the problem with general supply constraints which are given as an independence system defined over the items.The constraints,for example,can be a number of linear constraints or matroids.This captures the situation where items do not pre-exist,but are produced in reflection of consumer valuation of the items under the limit of resources.This paper focuses on the case of unit-demand consumers.In the setting,there are n consumers and m items; each item may be produced in multiple copies.Each consumer i ∈ [n] has a valuation vij on item j in the set Si in which he/she is interested.He/she must be allocated (if any) an item which gives the maximum (non-negative) utility.Suppose we are given an α-approximation oracle for finding the maximum weight independent set for the given independence system (or a slightly stronger oracle); for a large number of natural and interesting supply constraints,constant approximation algorithms are available.We obtain the following results.1) O(α log n)-approximation for the general case.2) O(αk)-approximation when each consumer is interested in at most k distinct types of items.3) O(αf)-approximation when each type of item is interesting to at most f consumers.Note that the final two results were previously unknown even without the independence system constraint.

  19. Dog Walking and Physical Activity in the United States

    Directory of Open Access Journals (Sweden)

    Sandra A. Ham, MS

    2006-03-01

    Full Text Available Introduction Dog walking is a purposeful physical activity that may have health benefits for humans and canines. A descriptive epidemiology of the contribution of dog walking to physically active lifestyles among dog walkers in the United States has not been previously reported. Methods Data on youth and adults who reported walking for pet care trips (N = 1282 on the National Household Travel Survey 2001 were analyzed for number of trips, proportion walking a dog for at least 10 minutes on one trip, and accumulation of 30 minutes or more in 1 day of walks lasting at least 10 minutes. Results In 1 day, 58.9% of dog walkers took two or more walks, 80.2% took at least one walk of 10 minutes or more, and 42.3% accumulated 30 minutes or more from walks lasting at least 10 minutes each. There were no significant differences by sex, family income, or categories of urbanization. Conclusion Walking a dog may contribute to a physically active lifestyle and should be promoted as a strategy that fits within the framework set forth by the Task Force on Community Preventive Services for Physical Activity.

  20. Glutarimides: Biological activity, general synthetic methods and physicochemical properties

    Directory of Open Access Journals (Sweden)

    Popović-Đorđević Jelena B.

    2015-01-01

    Full Text Available Glutarimides, 2,6-dioxopiperidines are compounds that rarely occur in natural sources, but so far isolated ones exert widespread pharmacological activities, which makes them valuable as potential pharmacotherapeutics. Glutarimides act as androgen receptor antagonists, anti-inflammatory, anxiolytics, antibacterials, and tumor suppressing agents. Some synthetic glutarimide derivatives are already in use as immunosuppressive and sedative (e.g., thalidomide or anxiolytics (buspirone drugs. The wide applicability of this class of compounds, justify the interest of scientists to explore new pathways for its syntheses. General methods for synthesis of six-membered imide ring, are presented in this paper. These methods include: a reaction of dicarboxylic acids with ammonia or primary amine, b reactions of cyclization: amido-acids, diamides, dinitriles, nitrilo-acids, amido-nitriles, amido-esters, amidoacyl-chlorides or diacyl-chlorides, c adition of carbon-monoxide on a,b-unsaturated amides, d oxidation reactions, e Michael adition of active methylen compounds on methacrylamide or conjugated amides. Some of the described methods are used for closing glutarimide ring in syntheses of farmacological active compounds sesbanimide and aldose reductase inhibitors (ARI. Analyses of the geometry, as well as, the spectroscopic analyses (NMR and FT-IR of some glutarimides are presented because of their broad spectrum of pharmacological activity. To elucidate structures of glutarimides, geometrical parameters of newly synthesized tert-pentyl-1-benzyl-4-methyl-glutarimide-3-carboxylate (PBMG are analyzed and compared with the experimental data from X-ray analysis for glutarimide. Moreover, molecular electrostatic potential (MEP surface which is plotted over the optimized geometry to elucidate the reactivity of PBMG molecule is analyzed. The electronic properties of glutarimide derivatives are explained on the example of thalidomide. The Frontier Molecular Orbital

  1. Diagnostic accuracy on the management of acute paediatric urinary tract infection in a general paediatric unit

    Institute of Scientific and Technical Information of China (English)

    Fahisham Taib; Bakht Jamal

    2015-01-01

    Objective: To ascertain diagnostic accuracy of paediatric urinary tract infection (UTI) in a general paediatric unit of a district hospital. Methods: Retrospective case note review and comparing to the final computerised database of Human in-Patient Enquiry (HIPE) at Portiuncula Hospital, Galway, Ireland. All children from 0-16 years of age with the diagnosis of UTI were enrolled within the 3 year study period. The information was first retrieved from HIPE system to capture list of patients. Case notes revision was followed to extract data under standardized pro-forma for demography, accuracy of diagnosis, treatment instituted and investigation ordered. Patients’ data was reviewed according to updated definition. Results: There were 85 cases treated for UTI during the 3 year period, and only 45 cases were considered as genuine UTI according to diagnostic criteria. Out of 45 cases, 16 cases were considered as suspected UTI cases. Escherichia coli was noted to be the commonest organism. Cephradine has been used as the first line treatment as per local guideline;however, different antibiotic regimes were based on physician’s preferences. The sensitivity of the current method of UTI diagnosis remained at 64%when comparing final diagnosis in the HIPE system. Conclusions: UTI can be difficult to accurately diagnosis in certain clinical cases. Decisions made should be individualized and tailored according to clinical suspicion and presentation of the patients. Improvement to ensure accurate diagnosis is vital to ensure correct data capture in the HIPE system thus giving valuable information and resource for future care.

  2. Practical Implementation of Prestack Kirchhoff Time Migration on a General Purpose Graphics Processing Unit

    Directory of Open Access Journals (Sweden)

    Liu Guofeng

    2016-08-01

    Full Text Available In this study, we present a practical implementation of prestack Kirchhoff time migration (PSTM on a general purpose graphic processing unit. First, we consider the three main optimizations of the PSTM GPU code, i.e., designing a configuration based on a reasonable execution, using the texture memory for velocity interpolation, and the application of an intrinsic function in device code. This approach can achieve a speedup of nearly 45 times on a NVIDIA GTX 680 GPU compared with CPU code when a larger imaging space is used, where the PSTM output is a common reflection point that is gathered as I[nx][ny][nh][nt] in matrix format. However, this method requires more memory space so the limited imaging space cannot fully exploit the GPU sources. To overcome this problem, we designed a PSTM scheme with multi-GPUs for imaging different seismic data on different GPUs using an offset value. This process can achieve the peak speedup of GPU PSTM code and it greatly increases the efficiency of the calculations, but without changing the imaging result.

  3. Practical Implementation of Prestack Kirchhoff Time Migration on a General Purpose Graphics Processing Unit

    Science.gov (United States)

    Liu, Guofeng; Li, Chun

    2016-08-01

    In this study, we present a practical implementation of prestack Kirchhoff time migration (PSTM) on a general purpose graphic processing unit. First, we consider the three main optimizations of the PSTM GPU code, i.e., designing a configuration based on a reasonable execution, using the texture memory for velocity interpolation, and the application of an intrinsic function in device code. This approach can achieve a speedup of nearly 45 times on a NVIDIA GTX 680 GPU compared with CPU code when a larger imaging space is used, where the PSTM output is a common reflection point that is gathered as I[ nx][ ny][ nh][ nt] in matrix format. However, this method requires more memory space so the limited imaging space cannot fully exploit the GPU sources. To overcome this problem, we designed a PSTM scheme with multi-GPUs for imaging different seismic data on different GPUs using an offset value. This process can achieve the peak speedup of GPU PSTM code and it greatly increases the efficiency of the calculations, but without changing the imaging result.

  4. A simple approach to calculate active power of electrosurgical units

    Directory of Open Access Journals (Sweden)

    André Luiz Regis Monteiro

    Full Text Available Abstract Introduction: Despite of more than a hundred years of electrosurgery, only a few electrosurgical equipment manufacturers have developed methods to regulate the active power delivered to the patient, usually around an arbitrary setpoint. In fact, no manufacturer has a method to measure the active power actually delivered to the load. Measuring the delivered power and computing it fast enough so as to avoid injury to the organic tissue is challenging. If voltage and current signals can be sampled in time and discretized in the frequency domain, a simple and very fast multiplication process can be used to determine the active power. Methods This paper presents an approach for measuring active power at the output power stage of electrosurgical units with mathematical shortcuts based on a simple multiplication procedure of discretized variables – frequency domain vectors – obtained through Discrete Fourier Transform (DFT applied on time-sampled voltage and current vectors. Results Comparative results between simulations and a practical experiment are presented – all being in accordance with the requirements of the applicable industry standards. Conclusion An analysis is presented comparing the active power analytically obtained through well-known voltage and current signals against a computational methodology based on vector manipulation using DFT only for time-to-frequency domain transformation. The greatest advantage of this method is to determine the active power of noisy and phased out signals with neither complex DFT or ordinary transform methodologies nor sophisticated computing techniques such as convolution. All results presented errors substantially lower than the thresholds defined by the applicable standards.

  5. Setting up a Paediatric Rapid Access Outpatient Unit: views of general practice teams.

    NARCIS (Netherlands)

    Williams, L.; Fryer, J.; Andrew, R.; Powell, C.; Pink, J.; Elwyn, G.

    2008-01-01

    BACKGROUND: Rapid Access Outpatient Units (RAOUs) have been suggested as an alternative to hospital inpatient units for the management of some acutely unwell children. These units can provide ambulatory care, delivered close to home, and may prevent unnecessary hospital admission. There are no quali

  6. Hurricane intensification along United States coast suppressed during active hurricane periods.

    Science.gov (United States)

    Kossin, James P

    2017-01-19

    The North Atlantic ocean/atmosphere environment exhibits pronounced interdecadal variability that is known to strongly modulate Atlantic hurricane activity. Variability in sea surface temperature (SST) is correlated with hurricane variability through its relationship with the genesis and thermodynamic potential intensity of hurricanes. Another key factor that governs the genesis and intensity of hurricanes is ambient environmental vertical wind shear (VWS). Warmer SSTs generally correlate with more frequent genesis and greater potential intensity, while VWS inhibits genesis and prevents any hurricanes that do form from reaching their potential intensity. When averaged over the main hurricane-development region in the Atlantic, SST and VWS co-vary inversely, so that the two factors act in concert to either enhance or inhibit basin-wide hurricane activity. Here I show, however, that conditions conducive to greater basin-wide Atlantic hurricane activity occur together with conditions for more probable weakening of hurricanes near the United States coast. Thus, the VWS and SST form a protective barrier along the United States coast during periods of heightened basin-wide hurricane activity. Conversely, during the most-recent period of basin-wide quiescence, hurricanes (and particularly major hurricanes) near the United States coast, although substantially less frequent, exhibited much greater variability in their rate of intensification, and were much more likely to intensify rapidly. Such heightened variability poses greater challenges to operational forecasting and, consequently, greater coastal risk during hurricane events.

  7. Hurricane intensification along United States coast suppressed during active hurricane periods

    Science.gov (United States)

    Kossin, James P.

    2017-01-01

    The North Atlantic ocean/atmosphere environment exhibits pronounced interdecadal variability that is known to strongly modulate Atlantic hurricane activity. Variability in sea surface temperature (SST) is correlated with hurricane variability through its relationship with the genesis and thermodynamic potential intensity of hurricanes. Another key factor that governs the genesis and intensity of hurricanes is ambient environmental vertical wind shear (VWS). Warmer SSTs generally correlate with more frequent genesis and greater potential intensity, while VWS inhibits genesis and prevents any hurricanes that do form from reaching their potential intensity. When averaged over the main hurricane-development region in the Atlantic, SST and VWS co-vary inversely, so that the two factors act in concert to either enhance or inhibit basin-wide hurricane activity. Here I show, however, that conditions conducive to greater basin-wide Atlantic hurricane activity occur together with conditions for more probable weakening of hurricanes near the United States coast. Thus, the VWS and SST form a protective barrier along the United States coast during periods of heightened basin-wide hurricane activity. Conversely, during the most-recent period of basin-wide quiescence, hurricanes (and particularly major hurricanes) near the United States coast, although substantially less frequent, exhibited much greater variability in their rate of intensification, and were much more likely to intensify rapidly. Such heightened variability poses greater challenges to operational forecasting and, consequently, greater coastal risk during hurricane events.

  8. Recent and past musical activity predicts cognitive aging variability: direct comparison with general lifestyle activities.

    Science.gov (United States)

    Hanna-Pladdy, Brenda; Gajewski, Byron

    2012-01-01

    Studies evaluating the impact of modifiable lifestyle factors on cognition offer potential insights into sources of cognitive aging variability. Recently, we reported an association between extent of musical instrumental practice throughout the life span (greater than 10 years) on preserved cognitive functioning in advanced age. These findings raise the question of whether there are training-induced brain changes in musicians that can transfer to non-musical cognitive abilities to allow for compensation of age-related cognitive declines. However, because of the relationship between engagement in general lifestyle activities and preserved cognition, it remains unclear whether these findings are specifically driven by musical training or the types of individuals likely to engage in greater activities in general. The current study controlled for general activity level in evaluating cognition between musicians and nomusicians. Also, the timing of engagement (age of acquisition, past versus recent) was assessed in predictive models of successful cognitive aging. Seventy age and education matched older musicians (>10 years) and non-musicians (ages 59-80) were evaluated on neuropsychological tests and general lifestyle activities. Musicians scored higher on tests of phonemic fluency, verbal working memory, verbal immediate recall, visuospatial judgment, and motor dexterity, but did not differ in other general leisure activities. Partition analyses were conducted on significant cognitive measures to determine aspects of musical training predictive of enhanced cognition. The first partition analysis revealed education best predicted visuospatial functions in musicians, followed by recent musical engagement which offset low education. In the second partition analysis, early age of musical acquisition (memory in musicians, while analyses for other measures were not predictive. Recent and past musical activity, but not general lifestyle activities, predicted variability

  9. A general method for determining secondary active transporter substrate stoichiometry

    Science.gov (United States)

    Fitzgerald, Gabriel A; Mulligan, Christopher; Mindell, Joseph A

    2017-01-01

    The number of ions required to drive substrate transport through a secondary active transporter determines the protein’s ability to create a substrate gradient, a feature essential to its physiological function, and places fundamental constraints on the transporter’s mechanism. Stoichiometry is known for a wide array of mammalian transporters, but, due to a lack of readily available tools, not for most of the prokaryotic transporters for which high-resolution structures are available. Here, we describe a general method for using radiolabeled substrate flux assays to determine coupling stoichiometries of electrogenic secondary active transporters reconstituted in proteoliposomes by measuring transporter equilibrium potentials. We demonstrate the utility of this method by determining the coupling stoichiometry of VcINDY, a bacterial Na+-coupled succinate transporter, and further validate it by confirming the coupling stoichiometry of vSGLT, a bacterial sugar transporter. This robust thermodynamic method should be especially useful in probing the mechanisms of transporters with available structures. DOI: http://dx.doi.org/10.7554/eLife.21016.001 PMID:28121290

  10. Aeromycological study at the intensive care unit of the "Dr. Manuel Gea Gonzalez" General Hospital

    Directory of Open Access Journals (Sweden)

    José Manuel Ríos-Yuil

    2012-10-01

    Full Text Available INTRODUCTION: An aeromycological study verifies the presence and quantifies the concentration of fungal propagules in the air. It is very important in the hospital setting because of the increasing numbers of immunosuppressed and severely ill patients. The objective of this study was to determine the concentration of fungi in the air of the intensive care unit (ICU of "Dr. Manuel Gea González" General Hospital. METHODS: This is a descriptive, observational cross-sectional study. Air samples were obtained with a single stage Thermo-Andersen Viable Particle Sampler (Thermo Electron Corporation -Massachusetts, U.S.A. in a Petri dish with potato dextrose agar for 15 minutes at two different times (morning and afternoon and heights (1 and 1.5 meters. The Petri dishes were incubated for five to seven days at 27ºC, the number of colonies was counted, and the total CFU/m³ was determined. The isolated fungal genera were identified by morphological features. Epi Info v. 3.4.3 © was used for statistical analysis. RESULTS: The mean concentration of fungi in the air of the ICU was 85.08 ± 29.19 CFU/m³; while in the outside air it was 84.3 ± 17.23 CFU/m³ (p = 0.96. The fungi isolated were: Cladosporium spp., Penicillium spp., Aspergillus spp. (non-fumigatus, Fusarium spp., Exophiala spp., Syncephalastrum spp., and Acremonium spp. DISCUSSION: Fungal spores were found in the air of the ICU and Cladosporium spp. was the most frequently isolated fungi. There was no difference according to sampling time or height.

  11. Information-Theoretic Active SOM for Improving Generalization Performance

    Directory of Open Access Journals (Sweden)

    Ryotaro Kamimura

    2016-10-01

    Full Text Available In this paper, we introduce a new type of information-theoretic method called “information-theoretic active SOM”, based on the self-organizing maps (SOM for training multi-layered neural networks. The SOM is one of the most important techniques in unsupervised learning. However, SOM knowledge is sometimes ambiguous and cannot be easily interpreted. Thus, we introduce the information-theoretic method to produce clearer and interpretable representations. The present method extends this information-theoretic approach into supervised learning. The main contribution can be summarized by three points. First, it is shown that clear representations by the information-theoretic method can be effective in training supervised learning. Second, the method is sufficiently simple where there are two separated components, namely, information maximization and error minimization component. Usually, two components are mixed in one framework, and it is difficult to compromise between them. In addition, the knowledge obtained by this information-theoretic SOM can be used to solve the shortage of unlabeled data, because the information maximization component is unsupervised and can process all input data with and without labels. The method was applied to the well-known image segmentation datasets. Experimental results showed that clear weights were produced and generalization performance was improved by using the information-theoretic SOM. In addition, the final results were stable, almost independent of the parameter values.

  12. Forty Years of the United Nations General Assembly Resolution 3379 (XXX on Zionism and Racism: the Brazilian Vote as an instance of United States - Brazil Relations

    Directory of Open Access Journals (Sweden)

    NORMA BREDA DOS SANTOS

    2015-12-01

    Full Text Available Abstract In 1975, Brazil voted in favor of the United Nations General Assembly resolution 3379 (XXX, equating Zionism with a form of racism. Focusing on the decision-making process of president Ernesto Geisel's (1974-1979 foreign policy, "responsible pragmatism", this article discusses how the ultimate decision to vote in favor of resolution was taken taking into account mainly US-Brazil relationship.

  13. India: General Survey Unit for World Civilization Course Curriculum Project. Fulbright-Hays Summer Seminars Abroad, 1997 (India).

    Science.gov (United States)

    Brinton, Victoria

    This unit is intended to provide high school students with a general knowledge of the history and culture of India. Lessons include: (1) "Early India"; (2) "Indian Civilization 1500 BC - 500 AD: Hinduism"; (3) "Buddhism"; (4) "Indian Empires"; (5) "Indian Empires, Continued"; (6)…

  14. Collaboration of general practitioners and exercise providers in promotion of physical activity a written survey among general practitioners

    NARCIS (Netherlands)

    Leemrijse, C J; de Bakker, D H; Ooms, L; Veenhof, C

    2015-01-01

    BACKGROUND: General practitioners have an ideal position to motivate inactive patients to increase their physical activity. Most patients are able to exercise in regular local facilities outside the health care setting. The purpose of this study was to get insight into general practitioners percepti

  15. Collaboration of general practitioners and exercise providers in promotion of physical activity a written survey among general practitioners.

    NARCIS (Netherlands)

    Leemrijse, C.J.; Bakker, D.H. de; Ooms, L.; Veenhof, C.

    2015-01-01

    Background: General practitioners have an ideal position to motivate inactive patients to increase their physical activity. Most patients are able to exercise in regular local facilities outside the health care setting. The purpose of this study was to get insight into general practitioners percepti

  16. Mortality Analysis of Trauma Patients in General Intensive Care Unit of a State Hospital

    Directory of Open Access Journals (Sweden)

    İskender Kara

    2015-08-01

    Full Text Available Objective: The aim of this study was to determine the mortality rate and factors affecting the mortality of trauma patients in general intensive care unit (ICU of a state hospital. Material and Method: Data of trauma patients hospitalized between January 2012 and March 2013 in ICU of Konya Numune Hospital were retrospectively analyzed. Demographic characteristics and clinical data of patients were recorded. Patients were divided into two groups as survivors and dead. Mortality rate and factors affectin mortality were examined. Results: A total of 108 trauma patients were included in the study. The mortality rate of overall group was 19.4%. Median age of the patients was 44.5 years and 75.9% of them were males. Median Glasgow Coma Scale of death group was lower (5 (3-8 vs. 15 (13-15, p<0.0001, median APACHE II score was higher (20 (15-26 vs. 10 (8-13, p<0.0001 and median duration of ICU stay was longer (27 (5-62,5 vs. 2 (1-5, p<0.0001 than those in the survival group. The most common etiology of trauma was traffic accidents (47.2% and 52.7% of patients had head trauma. The rate of patients with any fracture was significantly higher in the survival group (66.7% vs. 33.3%, p=0.007. The rate of erythrocyte suspension, fresh frozen plasma, trombocyte suspension and albumin were 38.9%, 27.8%, 0.9% and 8.3%, respectively in all group. The number of patients invasive mechanically ventilated was 27.8% and median length of stay of these patients were 5 (1.75-33.5 days. The rate of operated patients was 42.6%. The rate of tracheostomy, renal replacement therapy, bronchoscopy and percutaneous endoscopic gastrostomy enforcements were higher in the death group. The advanced age (p=0.016, OR: 1.054; 95% CI: 1.010-1100 and low GCS (p<0.0001, OR: 0.583; 95% CI: 0.456-0.745 were found to be independent risk factors the ICU mortality of trauma patients in logistic regression analysis. Conclusion: We believe that the determination of these risk factors affecting

  17. The clinical pathway for hypertensive patient of local health unit, hospitals and general practitioners, the Milan experience.

    Science.gov (United States)

    Donzelli, Alberto; Sghedoni, Donatella; Carelli, Francesco A; Chirchiglia, Saverio; Manunta, Paolo

    2011-01-01

    The Clinical Pathway (in its complete definition Diagnostic, Clinical and Therapeutic Pathway - Percorso Diagnostico Terapeutico Assistenziale - PDTA), originally started to deal with the newly diagnosed hypertensive patient, developed also recommendations for the first-line drugs in case of specific indications/contraindications and organ damages. It has been developed by a working group of specialists in cardiology, nephrology, internal medicine (faculty included) designated by their hospitals (both public and private accredited), including all the main city hospitals, by general practitioners designated by the Medical Unions SNAMI, FIMMG, SMI and SiMI and by public health doctors belonging to the Local Health Unit of Milan, who have coordinated the proceedings and have guaranteed that possible conflicts of interest of single participants could not interfere with the PDTA, anyway approved by all in July 2009. The PDTA deals with the measuring and self- home-monitoring of blood pressure (BP) and the diagnosis of hypertension; it revises, sometimes "dries up" and rationalizes the recommendations for diagnostic tests and specialist evaluations; it develops prevention and non-pharmacological treatments, proposing also tools for patients and for prescribing correct nutrition and physical activity and a structured program for BP monitoring; but the main feature is the innovations brought in the proposed drug treatment in comparison with the current clinical practice.

  18. Aeroelastic code development activities in the United States

    Energy Technology Data Exchange (ETDEWEB)

    Wright, A.D. [National Renewable Energy Lab., Golden, Colorado (United States)

    1996-09-01

    Designing wind turbines to be fatigue resistant and to have long lifetimes at minimal cost is a major goal of the federal wind program and the wind industry in the United States. To achieve this goal, we must be able to predict critical loads for a wide variety of different wind turbines operating under extreme conditions. The codes used for wind turbine dynamic analysis must be able to analyze a wide range of different wind turbine configurations as well as rapidly predict the loads due to turbulent wind inflow with a minimal set of degrees of freedom. Code development activities in the US have taken a two-pronged approach in order to satisfy both of these criteria: (1) development of a multi-purpose code which can be used to analyze a wide variety of wind turbine configurations without having to develop new equations of motion with each configuration change, and (2) development of specialized codes with minimal sets of specific degrees of freedom for analysis of two- and three-bladed horizontal axis wind turbines and calculation of machine loads due to turbulent inflow. In the first method we have adapted a commercial multi-body dynamics simulation package for wind turbine analysis. In the second approach we are developing specialized codes with limited degrees of freedom, usually specified in the modal domain. This paper will summarize progress to date in the development, validation, and application of these codes. (au) 13 refs.

  19. Caffeine consumption among active duty United States Air Force personnel.

    Science.gov (United States)

    Knapik, Joseph J; Austin, Krista G; McGraw, Susan M; Leahy, Guy D; Lieberman, Harris R

    2017-07-01

    Data from the National Health and Nutrition Examination Survey (NHANES) indicated that 89% of Americans regularly consumed caffeinated products, but these data did not include military personnel. This cross-sectional study examined caffeine consumption prevalence, amount of daily consumption, and factors associated with caffeine intake in active duty United States (US) Air Force personnel. Service members (N = 1787) stationed in the US and overseas completed a detailed questionnaire describing their intake of caffeine-containing products in addition to their demographic, lifestyle, and military characteristics. Overall, 84% reported consuming caffeinated products ≥1 time/week with caffeine consumers ingesting a mean ± standard error of 212 ± 9 mg/day (224 ± 11 mg/day for men, 180 ± 12 mg/day for women). The most commonly consumed caffeinated products (% users) were sodas (56%), coffee (45%), teas (36%), and energy drinks (27%). Multivariate logistic regression modeling indicated that characteristics independently associated with caffeine consumption (≥1 time/week) included older age, ethnicity other than black, tobacco use, less aerobic training, and less sleep; energy drink use was associated with male gender, younger age, tobacco use, and less sleep. Compared to NHANES data, the prevalence of caffeine consumption in Air Force personnel was similar but daily consumption (mg/day) was higher. Published by Elsevier Ltd.

  20. Special Inspector General for Iraq Reconstruction. Quaterly and Semiannual Report to the United States Congress

    Science.gov (United States)

    2007-07-30

    Electricity Sector engineers, who provided day-to-day technical supervision and implementation management of GRD’s plan to bring Units 5 and 6 online ...telephone, mail, fax, and online contacts from people in Iraq, the United States, and throughout the world. Second quarter Reporting As of June 30, 2007...Investigative Task Force for Iraq Reconstruction SPOC Sector Project and Contracting Office Contractor TAMU Texas A&M University TBI Trade Bank of Iraq

  1. Special Inspector General for Iraq Reconstruction: Quarterly Report and Semiannual Report to the United States Congress

    Science.gov (United States)

    2007-07-30

    Sector engineers, who provided day-to-day technical supervision and implementation management of GRD’s plan to bring Units 5 and 6 online . GRD...fax, and online contacts from people in Iraq, the United States, and throughout the world. Second quarter Reporting As of June 30, 2007, SIGIR...Task Force for Iraq Reconstruction SPOC Sector Project and Contracting Office Contractor TAMU Texas A&M University TBI Trade Bank of Iraq TF-BSO

  2. Unit 1b: A General Approach to the Teaching of Architecture

    DEFF Research Database (Denmark)

    Toft, Anne Elisabeth

    2011-01-01

    The chapter presents the overall academic aims of the teaching at Unit 1b and how these were implemented in the curriculum for 2009/2010. The section includes considerations about learning targets, method, discourse, pedagogy and didactics.......The chapter presents the overall academic aims of the teaching at Unit 1b and how these were implemented in the curriculum for 2009/2010. The section includes considerations about learning targets, method, discourse, pedagogy and didactics....

  3. The satiety signaling neuropeptide perisulfakinin inhibits the activity of central neurons promoting general activity

    Directory of Open Access Journals (Sweden)

    Dieter Wicher

    2007-12-01

    Full Text Available The metabolic state is one of the determinants of the general activity level. Satiety is related to resting or sleep whereas hunger correlates to wakefulness and activity. The counterpart to the mammalian satiety signal cholecystokinin (CCK in insects are the sulfakinins. The aim of this study was to resolve the mechanism by which the antifeedant activity of perisulfakinin (PSK in Periplaneta americana is mediated. We identified the sources of PSK which is used both as hormone and as paracrine messenger. PSK is found in the neurohemal organ of the brain and in nerve endings throughout the central nervous system. To correlate the distributions of PSK and its receptor (PSKR, we cloned the gene coding for PSKR and provide evidence for its expression within the nervous system. It occurs only in a few neurons, among them are the dorsal unpaired median (DUM neurons which release octopamine thereby regulating the general level of activity. Application of PSK to DUM neurons attenuated the spiking frequency (EC50=11pM due to reduction of a pacemaker Ca2+ current through cAMP-inhibited pTRPγ channels. PSK increased the intracellular cAMP level while decreasing the intracellular Ca2+ concentration in DUM neurons. Thus, the satiety signal conferred by PSK acts antagonistically to the hunger signal, provided by the adipokinetic hormone (AKH: PSK depresses the electrical activity of DUM neurons by inhibiting the pTRPγ channel that is activated by AKH under conditions of food shortage.

  4. Expectations and needs of persons with family members in an intensive care unit as opposed to a general ward.

    Science.gov (United States)

    Foss, K R; Tenholder, M F

    1993-04-01

    The positive effect of family support on the outcome from serious illness that requires intensive care has been recognized by clinicians for decades. We have all seen that family visitation and an intensive care environment more similar to that of a general ward (sunlight, radio, television) can benefit patients with psychosis related to intensive care. The severity of illness of the individual patient exerts a powerful stress on the family unit, but it has been difficult to measure this effect. We used a 40-question family needs survey with a degree of importance scale to compare the intensive care unit (ICU) with the general ward in terms of impact on the family. Five needs were found to discriminate these two environments. The family members of patients in an ICU considered it very important (1) for staff to give directions on what to do at the bedside, (2) to receive more support from their own family unit, (3) to have a place to be alone as a family unit in the hospital, (4) to be informed in advance of any transfer plan, and (5) to have flexibility in the time allowed for visitation. Family members are willing to accept decreased visitation time if the physicians and nurses can equate this decrease with the complexity of care in the ICU. The results of this survey have helped us modify and individualize our approach based on family expectations especially when patients are transferred from the general ward to the ICU or from the ICU to the ward.

  5. Conformity to the surviving sepsis campaign international guidelines among physicians in a general intensive care unit in Nairobi.

    Science.gov (United States)

    Mung'ayi, V; Karuga, R

    2010-08-01

    There are emerging therapies for managing septic critically-ill patients. There is little data from the developing world on their usage. To determine the conformity rate for resuscitation and management bundles for septic patients amongst physicians in a general intensive care unit. Cross sectional observational study. The general intensive care unit, Aga Khan University Hospital,Nairobi. Admitting physicians from all specialties in the general intensive care unit. The physicians had high conformity rates of 92% and 96% for the fluid resuscitation and use of va so pressors respectively for the initial resuscitation bundle. They had moderate conformity rates for blood cultures prior to administering antibiotics (57%) and administration of antibiotics within first hour of recognition of septic shock (54%). There was high conformity rate to the glucose control policy (81%), use of protective lung strategy in acute lung injury/Acute respiratory distress syndrome, venous thromboembolism prophylaxis (100%) and stress ulcer prophylaxis (100%) in the management bundle. Conformity was moderate for use of sedation, analgesia and muscle relaxant policy (69%), continuous renal replacement therapies (54%) and low for steroid policy (35%), administration ofdrotrecogin alfa (0%) and selective digestive decontamination (15%). There is varying conformity to the international sepsis guidelines among physicians caring for patients in our general ICU. Since increased conformity would improve survival and reduce morbidity, there is need for sustained education and guideline based performance improvement.

  6. Active structural elements within a general vibration control framework

    OpenAIRE

    Holterman, J.; de Vries, Theodorus J.A.; Isermann, R.

    2000-01-01

    High-precision machines typically suffer from small but annoying vibrations. As the most appropriate solution to a particular vibration problem is not always obvious, it may be convenient to cast the problem in a more general framework. This framework may then be used for frequency response analysis, which, together with close examination of the disturbance sources, leads to a solution in general structural terms, like ‘vibration isolation’, ‘stiffness enhancement’ or ‘damping augmentation’. ...

  7. The experience of registered nurses nursing in the general audit intensive care unit

    Directory of Open Access Journals (Sweden)

    E. Pope

    1998-09-01

    Full Text Available In this article a phenomenological qualitative research study is discussed. More attention will be given to the methodology of the research. The objectives of the study are two-fold: firstly to explore and describe the experience of registered nurses nursing in the adult intensive care unit (this is the first phase of the research and to describe guidelines based on the information obtained in the first phase to support the nurses in the form of a support programme in the second phase. The units of research are the registered nurses in the intensive care unit. The characteristics of the unit of research led to the emergence of a qualitative phenomenological research design of an explorative, descriptive and contextual nature. In the discussion of research methodology attention will be given to phase one: data gathering (ethical considerations and informed consent; purposive selection, phenomenological interviews and field notes; data analysis (Tesch’s method of data analysis, methods to ensure trustworthiness, organisation of raw data and integration of findings supported by literature. Five themes were identified through the data analysis: impaired communication with management; discrimination: white on black racism; lack of fair, competitive remuneration and disregard for professional worth; non-conducive physical environment, and stressful working environment. Phase two: Guidelines were described to support the registered nurses in the intensive care unit based on the information obtained in phase one of the research.

  8. Signature of the Collaboration Agreement between THE UNITED NATIONS INSTITUTE FOR TRAINING AND RESEARCH (UNITAR), by Mr Carlos Lopes (UN Assistant Secretary-General and Executive Director of UNITAR) and by the Director General of CERN, Mr Robert Aymar

    CERN Multimedia

    Claudia Marcelloni

    2008-01-01

    Signature of the Collaboration Agreement between THE UNITED NATIONS INSTITUTE FOR TRAINING AND RESEARCH (UNITAR), by Mr Carlos Lopes (UN Assistant Secretary-General and Executive Director of UNITAR) and by the Director General of CERN, Mr Robert Aymar

  9. The data submitted by the United Kingdom to the United Nations Scientific Committee on the Effects of Atomic Radiation for the 1977 report to the General Assembly

    CERN Document Server

    Taylor, F E; Webb, G A M

    1976-01-01

    The United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) was established by the General Assembly in 1955 to report on the exposure of man to ionising radiation. In the subsequent twenty years the Committee has covered most aspects of the subject with repeated reviews of the levels of exposure from fallout due to weapons testing. The Committee is currently preparing a further report on doses from all sources and an evaluation of their biological effects. This is expected to be published in 1977. To aid it in compiling this report the Committee requested Member States of the UN to submit national data on a wide range of sources of exposure. The Board was asked by the Foreign and Commonwealth Office to collate the information requested from the United Kingdom. Data were available in the scientific literature on some topics, such as medical irradiation and environmental radioactivity. On some other topics, particularly occupational exposure, data have been collected but seldom publishe...

  10. Water-temperature data acquisition activities in the United States

    Science.gov (United States)

    Pauszek, F.H.

    1972-01-01

    Water Data Coordination, U.S. Geological Survey, and published in the "Catalog of Information on Water Data, Index to Water Quality Section, Edition 1970." This is one of four indexes, each of which is a separate section of the Catalog. Three of the indexes, "Index to Water-Quality Section," "Index to Surface-Water Section," and "Index to Ground-.Water Stations," contain information on data acquired on a recurrent basis at specific locations for a period of 3 years or more. The fourth section, "Index to Areal Investigations and Miscellaneous Activities," is concerned with specific projects or shorter-term data activities that involve field or laboratory measurements or observations not included in any other section of the Catalog. The Catalog is a record of activities throughout the country (and in some places along the international border between the United States and Canada) conducted by Federal and non-Federal agencies engaged in the acquisition of water data and who furnish such information for presentation in the Catalog. The Catalog itself is an outgrowth of an assignment to the Department of the Interior and in turn to the Geological Survey, by the Office of Management and Budget, through the medium of OMB Circular A-67. This Circular states in part that one of the assigned responsibilities will be maintenance of a "central catalog of information on...water data and on Federal activities being planned or conducted to acquire such data." As an extension of this activity, non-Federal agencies are solicited to participate in the program. In this report, information is presented by means of tables and illustrations preceded by brief explanations. It includes the agencies collecting the data, the number of stations located on surface and ground waters where temperature measurements are made, the distribution of stations by States and by the 21 regions of the Water Resources Council (WRC) (a Federal agency created in accordance with the Water Resources Planning Act of

  11. 47 CFR 76.2000 - Exclusive access to multiple dwelling units generally.

    Science.gov (United States)

    2010-10-01

    ... gated community, mobile home park, or garden apartment); provided however, that MDU shall not include..., Exemption from 76.70 Channel access enforcement 76.10 Communities, Designated 76.51 Community, Principal contour 76.5 Community unit 76.5 Consumer education-selector switches 76.66 Cross-ownership 76.501...

  12. Reducing costs by clustering maintenance activities for multiple critical units

    NARCIS (Netherlands)

    de Jonge, Bram; Klingenberg, Warse; Teunter, Ruud; Tinga, Tiedo

    Advances in sensor technology have enabled companies to make significant progress towards achieving condition-based maintenance (CBM). CBM provides the opportunity to perform maintenance actions more effectively. However, scheduling maintenance at the unit level may imply a high maintenance

  13. An analysis of acute admissions to a general hospital psychiatric unit

    African Journals Online (AJOL)

    QuickSilver

    Statistics for 1999 showed that Helen Joseph Hospital admits on the average 53 new .... Lund C & Flisher AJ. South African Mental Health Process Indicators. .... paper) will fall well on the ears of general hospital management. Moosa and ...

  14. Interferon Type I Driven Immune Activation in Generalized Autoimmune Diseases

    NARCIS (Netherlands)

    Z. Brkić (Zana)

    2013-01-01

    textabstractThis thesis describes research performed on several generalized autoimmune diseases with the main focus on primary Sjögren’s syndrome. Interferon type I has been implicated in the pathogenesis of these diseases and will be introduced in this chapter together with other important immune f

  15. Technology, Active Learning, and Retention in General Education Mathematics

    Science.gov (United States)

    Levi, Inessa; Chahine, Iman; Garrett, Lauretta; Wang, Haifeng

    2016-01-01

    Difficulties in general education mathematics courses may be attributed to many factors, primarily low proficiency in symbol manipulation, a perception that mathematics is an area which eludes mastery, a lack of engagement and effective practice. Educational technology can be a powerful aid in overcoming these factors. This work describes the…

  16. Active structural elements within a general vibration control framework

    NARCIS (Netherlands)

    Holterman, J.; de Vries, Theodorus J.A.; Isermann, R.

    2000-01-01

    High-precision machines typically suffer from small but annoying vibrations. As the most appropriate solution to a particular vibration problem is not always obvious, it may be convenient to cast the problem in a more general framework. This framework may then be used for frequency response

  17. IFLA General Conference, 1985. Division on Regional Activities. Papers.

    Science.gov (United States)

    International Federation of Library Associations, The Hague (Netherlands).

    Papers on regional library activities which were presented at the 1985 International Federation of Library Associations (IFLA) conference include: (1) "Importance of Information Resources in National Development with Particular Reference to the Asian Scene" (Yogendra P. Dubey, India); (2) "Report of the Activities of the Regional…

  18. Preparing General Purpose Forces in the United States and British Armies for Counterinsurgent Operations

    Science.gov (United States)

    2010-12-10

    commander whose book Learning to Eat Soup with a Knife, was widely read by military leaders serving in Afghanistan and Iraq. Dr. Nagl also...sustainment training for units while deployed to Malaya.23 Arthur Campbell , a company commander in the Suffolk Regiment who served in Malaya in the early 1950s...Learning to Eat Soup with a Knife: Counterinsurgency Lessons from Malaya and Vietnam, comparing the Malayan Emergency and Vietnam War is akin to

  19. Managing Highway Maintenance: Maintenance Activities, Work Units, and Classifying Work, Unit 6, Level 2.

    Science.gov (United States)

    Federal Highway Administration (DOT), Washington, DC. Offices of Research and Development.

    Part of the series "Managing Highway Maintenance," the unit explains how maintenance work should be described, measured, and classified. It is designed for supervisors who need to know the mechanics of describing work. The format is a programed, self-instruction approach in which information is presented in progressive segments or…

  20. Adapting generalization tools to physiographic diversity for the united states national hydrography dataset

    Science.gov (United States)

    Buttenfield, B.P.; Stanislawski, L.V.; Brewer, C.A.

    2011-01-01

    This paper reports on generalization and data modeling to create reduced scale versions of the National Hydrographic Dataset (NHD) for dissemination through The National Map, the primary data delivery portal for USGS. Our approach distinguishes local differences in physiographic factors, to demonstrate that knowledge about varying terrain (mountainous, hilly or flat) and varying climate (dry or humid) can support decisions about algorithms, parameters, and processing sequences to create generalized, smaller scale data versions which preserve distinct hydrographic patterns in these regions. We work with multiple subbasins of the NHD that provide a range of terrain and climate characteristics. Specifically tailored generalization sequences are used to create simplified versions of the high resolution data, which was compiled for 1:24,000 scale mapping. Results are evaluated cartographically and metrically against a medium resolution benchmark version compiled for 1:100,000, developing coefficients of linear and areal correspondence.

  1. 从图形处理器到基于GPU的通用计算%From Graphic Processing Unit to General Purpose Graphic Processing Unit

    Institute of Scientific and Technical Information of China (English)

    刘金硕; 刘天晓; 吴慧; 曾秋梅; 任梦菲; 顾宜淳

    2013-01-01

    对GPU(graphic process unit)、基于GPU的通用计算(general purpose GPU,GPGPU)、基于GPU的编程模型与环境进行了界定;将GPU的发展分为4个阶段,阐述了GPU的架构由非统一的渲染架构到统一的渲染架构,再到新一代的费米架构的变化;通过对基于GPU的通用计算的架构与多核CPU架构、分布式集群架构进行了软硬件的对比.分析表明:当进行中粒度的线程级数据密集型并行运算时,采用多核多线程并行;当进行粗粒度的网络密集型并行运算时,采用集群并行;当进行细粒度的计算密集型并行运算时,采用GPU通用计算并行.最后本文展示了未来的GPGPU的研究热点和发展方向--GPGPU自动并行化、CUDA对多种语言的支持、CUDA的性能优化,并介绍了GPGPU的一些典型应用.%This paper defines the outline of GPU(graphic processing unit) , the general purpose computation, the programming model and the environment for GPU. Besides, it introduces the evolution process from GPU to GPGPU (general purpose graphic processing unit) , and the change from non-uniform render architecture to the unified render architecture and the next Fermi architecture in details. Then it compares GPGPU architecture with multi-core GPU architecture and distributed cluster architecture from the perspective of software and hardware. When doing the middle grain level thread data intensive parallel computing, the multi-core and multi-thread should be utilized. When doing the coarse grain network computing, the cluster computing should be utilized. When doing the fine grained compute intensive parallel computing, the general purpose computation should be adopted. Meanwhile, some classical applications of GPGPU have been mentioned. At last, this paper demonstrates the further developments and research hotspots of GPGPU, which are automatic parallelization of GPGPU, multi-language support and performance optimization of CUDA, and introduces the classic

  2. Tristable and multiple bistable activity in complex random binary networks of two-state units

    CERN Document Server

    Christ, Simon; Schimansky-Geier, Lutz

    2016-01-01

    We study complex networks of stochastic two-state units. Our aim is to model discrete stochastic excitable dynamics with a rest and an excited state. These two states are assumed to possess different waiting time distributions. The rest state is treated as an activation process with an exponentially distributed life time, whereas the latter in the excited state shall have a constant mean which may originate from any distribution. The activation rate of any single unit is determined by its neighbors according to a random complex network structure. In order to treat this problem in an analytical way, we use a heterogeneous mean-field approximation yielding a set of equations general valid for uncorrelated random networks. Based on this derivation we focus on random binary networks where the network is solely comprised of nodes with either of two degrees. The ratio between the two degrees is shown to be a crucial parameter. Dependent on the composition of the network the steady states show the usual transition f...

  3. Special Inspector General for Iraq Reconstruction Quarterly Report to the United States Congress

    Science.gov (United States)

    2009-10-30

    and to introduce salt-tolerant Bermuda grass into Iraq674 Th e PRT also met with German investors in- terested in establishing car dealerships in... Triangle Institute International SET Security Escort Team SIGAR Special Inspector General for Afghanistan Reconstruction SIGIR Special Inspector

  4. General and Partial Equilibrium Modeling of Sectoral Policies to Address Climate Change in the United States

    Energy Technology Data Exchange (ETDEWEB)

    Pizer, William; Burtraw, Dallas; Harrington, Winston; Newell, Richard; Sanchirico, James; Toman, Michael

    2003-03-31

    This document provides technical documentation for work using detailed sectoral models to calibrate a general equilibrium analysis of market and non-market sectoral policies to address climate change. Results of this work can be found in the companion paper, "Modeling Costs of Economy-wide versus Sectoral Climate Policies Using Combined Aggregate-Sectoral Model".

  5. Inclusive Education in the United States: Middle School General Education Teachers' Approaches to Inclusion

    Science.gov (United States)

    Mackey, Megan

    2014-01-01

    Research examined how three middle school teachers included students with disabilities in their general education classrooms. Purposive sampling was used to select a sixth grade science teacher, seventh grade social studies teacher, and eighth grade math teacher whose classrooms were identified as exemplifying the characteristics of inclusive…

  6. How Outpatient Substance Abuse Treatment Unit Director Activities May Affect Provision of Community Outreach Services

    Science.gov (United States)

    Chuang, Emmeline; Wells, Rebecca; Alexander, Jeffrey; Green, Sherri

    2013-01-01

    Aims: Community outreach services play an important role in infectious disease prevention and engaging drug users not currently in treatment. However, fewer than half of US substance abuse treatment units provide these services and many have little financial incentive to do so. Unit directors generally have latitude about scope of services,…

  7. How Outpatient Substance Abuse Treatment Unit Director Activities May Affect Provision of Community Outreach Services

    Science.gov (United States)

    Chuang, Emmeline; Wells, Rebecca; Alexander, Jeffrey; Green, Sherri

    2013-01-01

    Aims: Community outreach services play an important role in infectious disease prevention and engaging drug users not currently in treatment. However, fewer than half of US substance abuse treatment units provide these services and many have little financial incentive to do so. Unit directors generally have latitude about scope of services,…

  8. Risk factors associated with bus accident severity in the United States: A generalized ordered logit model

    DEFF Research Database (Denmark)

    Kaplan, Sigal; Prato, Carlo Giacomo

    2012-01-01

    Introduction: Recent years have witnessed a growing interest in improving bus safety operations worldwide. While in the United States buses are considered relatively safe, the number of bus accidents is far from being negligible, triggering the introduction of the Motor-coach Enhanced Safety Act...... that accident severity increases: (i) for young bus drivers under the age of 25; (ii) for drivers beyond the age of 55, and most prominently for drivers over 65 years old; (iii) for female drivers; (iv) for very high (over 65 mph) and very low (under 20 mph) speed limits; (v) at intersections; (vi) because...

  9. Infusing Active Learning into the Research Methods Unit

    Science.gov (United States)

    Bluestone, Cheryl

    2007-01-01

    The research methods unit of survey psychology classes introduces important concepts of scientific reasoning and fluency, making it an ideal course in which to deliver enhanced curricula. To increase interest and engagement, the author developed an expanded research methods and statistics module to give students the opportunity to explore…

  10. Age-Related Declines in General Cognitive Abilities of Balb/C Mice and General Activity Are Associated with Disparities in Working Memory, Body Weight, and General Activity

    Science.gov (United States)

    Matzel, Louis D.; Grossman, Henya; Light, Kenneth; Townsend, David; Kolata, Stefan

    2008-01-01

    A defining characteristic of age-related cognitive decline is a deficit in general cognitive performance. Here we use a testing and analysis regimen that allows us to characterize the general learning abilities of young (3-5 mo old) and aged (19-21 mo old) male and female Balb/C mice. Animals' performance was assessed on a battery of seven diverse…

  11. Analysis of impact of general-purpose graphics processor units in supersonic flow modeling

    Science.gov (United States)

    Emelyanov, V. N.; Karpenko, A. G.; Kozelkov, A. S.; Teterina, I. V.; Volkov, K. N.; Yalozo, A. V.

    2017-06-01

    Computational methods are widely used in prediction of complex flowfields associated with off-normal situations in aerospace engineering. Modern graphics processing units (GPU) provide architectures and new programming models that enable to harness their large processing power and to design computational fluid dynamics (CFD) simulations at both high performance and low cost. Possibilities of the use of GPUs for the simulation of external and internal flows on unstructured meshes are discussed. The finite volume method is applied to solve three-dimensional unsteady compressible Euler and Navier-Stokes equations on unstructured meshes with high resolution numerical schemes. CUDA technology is used for programming implementation of parallel computational algorithms. Solutions of some benchmark test cases on GPUs are reported, and the results computed are compared with experimental and computational data. Approaches to optimization of the CFD code related to the use of different types of memory are considered. Speedup of solution on GPUs with respect to the solution on central processor unit (CPU) is compared. Performance measurements show that numerical schemes developed achieve 20-50 speedup on GPU hardware compared to CPU reference implementation. The results obtained provide promising perspective for designing a GPU-based software framework for applications in CFD.

  12. 31 CFR 538.531 - Official activities of the United States Government and international organizations.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Official activities of the United States Government and international organizations. 538.531 Section 538.531 Money and Finance: Treasury....531 Official activities of the United States Government and international organizations. (a)...

  13. Applying Modern Techniques and Carrying Out English .Extracurricular—— On the Model United Nations Activity

    Institute of Scientific and Technical Information of China (English)

    XuXiaoyu; WangJian

    2004-01-01

    This paper is an introduction of the extracurricular activity of the Model United Nations in Northwestern Polyteehnical University (NPU) and it focuses on the application of the modem techniques in the activity and the pedagogical theories applied in it. An interview and questionnaire research will reveal the influence of the Model United Nations.

  14. An Evaluation of Shared Mental Models and Mutual Trust on General Medical Units: Implications for Collaboration, Teamwork, and Patient Safety.

    Science.gov (United States)

    McComb, Sara A; Lemaster, Matthew; Henneman, Elizabeth A; Hinchey, Kevin T

    2015-02-24

    This study examines nurse-physician teamwork and collaboration, a critical component in the delivery of safe patient care, on general medical units. To that end, we assess shared mental models and mutual trust, 2 coordinating mechanisms that help facilitate teamwork, among nurses and physicians working on general medical units. Data were collected from 37 nurses and 42 physicians at an urban teaching medical center in the Northeastern United States. Shared mental model questionnaire items were iteratively developed with experts' input to ensure content validity. Mutual trust items were adapted from an existing scale; items were reliable. Data were analyzed using χ and independent 2-tailed t tests. Physicians and nurses reported significant differences in their perceptions of the professional responsible for a variety of roles (e.g., advocating for the patient [P = 0.0007], identifying a near miss/error [P = 0.003]). Medication reconciliation is only role for which nurses perceive less responsibility than physicians perceive nurses have. Regarding mutual trust, both groups reported significantly more trust within their own professions; both groups reported similar levels of trust in physicians, with physicians reporting significantly less trust in their nursing colleagues than nurses perceive (P collaboration, more work is needed. To that end, we propose increasing knowledge about their respective roles, providing opportunities for nurse and physician collaboration through rounding or committee work and enhancing the preparedness and professionalism of interactions.

  15. Partnered medication review and charting between the pharmacist and medical officer in the Emergency Short Stay and General Medicine Unit.

    Science.gov (United States)

    Tong, Erica Y; Roman, Cristina P; Smit, De Villiers; Newnham, Harvey; Galbraith, Kirsten; Dooley, Michael J

    2015-08-01

    A partnered medication review and charting model involving a pharmacist and medical officer was implemented in the Emergency Short Stay Unit and General Medicine Unit of a major tertiary hospital. The aim of the study was to describe the safety and effectiveness of partnered medication charting in this setting. A partnered medication review and charting model was developed. Credentialed pharmacists charted pre-admission medications and venous thromboembolism prophylaxis in collaboration with the admitting medical officer. The pharmacist subsequently had a clinical discussion with the treating nurse regarding the medication management plan for the patient. A prospective audit was undertaken of all patients from the initiation of the service. A total of 549 patients had medications charted by a pharmacist from the 14th of November 2012 to the 30th of April 2013. A total of 4765 medications were charted by pharmacists with 7 identified errors, corresponding to an error rate of 1.47 per 1000 medications charted. Partnered medication review and charting by a pharmacist in the Emergency Short Stay and General Medicine unit is achievable, safe and effective. Benefits from the model extend beyond the pharmacist charting the medications, with clinical value added to the admission process through early collaboration with the medical officer. Further research is required to provide evidence to further support this collaborative model. Copyright © 2015. Published by Elsevier Ltd.

  16. Special Inspector General for Iraq Reconstruction. Quarterly Report and Semiannual report to the United States Congress

    Science.gov (United States)

    2009-07-30

    livestock can be raised more economically in confi nement imported 12,400 Hungarian fi ngerlings to • cross-breed with heat -resistant Iraqi carp to...local population, who are primarily engaged in trading, farming, and raising sheep and calves . Th e Deputy Inspector General for Iraq July2009.indb...the challenges Basrah faced in unemployment, corruption, and fi scal stress .716 Security Security improved slightly, with four bombs exploding this

  17. Active Learning in a Large General Physics Classroom.

    Science.gov (United States)

    Trousil, Rebecca

    2008-04-01

    In 2004, we launched a new calculus-based, introductory physics sequence at Washington University. Designed as an alternative to our traditional lecture-based sequence, the primary objectives for this new course were to actively engage students in the learning process, to significantly strengthen students' conceptual reasoning skills, to help students develop higher level quantitative problem solving skills necessary for analyzing ``real world'' problems, and to integrate modern physics into the curriculum. This talk will describe our approach, using The Six Ideas That Shaped Physics text by Thomas Moore, to creating an active learning environment in large classes as well as share our perspective on key elements for success and challenges that we face in the large class environment.

  18. A multi-resistant Acinetobacter baumannii outbreak in a general intensive care unit.

    Science.gov (United States)

    Levidiotou, Stamatina; Galanakis, Emmanouil; Vrioni, Georgia; Papamichael, Dimitrios; Nakos, Georgios; Stefanou, Dimitrios

    2002-01-01

    In an Intensive Care Unit, three patients were found infected and two colonized with multiresistant Acinetobacter baumannii within a period of one week. To identify the outbreak source, two surveillance studies were performed concerning patients and the environment. Genotyping of isolates was performed by random amplification of polymorphic DNA analysis (RAPD). Environmental sampling failed to yield A. baumannii, with the exception of a single sample from a trunking. RAPD-fingerprinting yielded identical patterns for all patient isolates including the trunking isolate, thus confirming the suspected cluster. Since the strain from the trunking had a susceptibility pattern and a RAPD pattern identical to that of the strains isolated from the patients, we believe that this was the likely source of the outbreak. In conclusion, A. baumannii outbreaks may be quickly controlled by appropriate action of the hospital infection staff. RAPD-fingerprinting may provide a useful and rapid identification technique for the epidemiological investigation of a hospital outbreak.

  19. Characteristics and outcomes of end-stage renal disease patients with active tuberculosis followed in intensive care units

    Directory of Open Access Journals (Sweden)

    Ulasli Sevinc

    2009-01-01

    Full Text Available Tuberculosis (TB remains a common problem in patients with chronic renal failure. In intensive care units, misdiagnosis or delayed diagnosis of TB is common. Therefore, a description of characteristics of active TB in patients with renal failure followed in intensive care units is important to reduce mortality and transmission of the disease. This study was performed to describe the characteristics of patients with renal failure admitted to the intensive care units and having active TB and evaluate predictive factors for in hospital mortality. The hospital records of 24 patients (11 women, 13 men having ESRD and TB between 2001-2006 were reviewed. Clinical, radiological, and laboratory data on admission were recorded. Possible parameters contributing to in-hospital mortality were obtained from the medical records. In-hospital mortality rate was 66.6%. Factors associated with mortality were decreased partial pressure of oxygen and malnutrition. Fever was reported in 8 patients and hemoptysis was reported in 3 patients. Eight patients had consolidation on chest radiograph, while 4 had normal findings Seventeen patients had pulmonary involvement, and 11 had extra pulmonary involvement. The mortality rate in TB patients followed in intensive care units is high, with 3 factors contributing to in-hospital mortality. Clinicians should consider active TB in renal failure patients being followed in the intensive care unit, even when results of a chest radiograph are normal especially in patients with unexplained poor general health or respiratory failure.

  20. Motor unit activity after eccentric exercise and muscle damage in humans.

    Science.gov (United States)

    Semmler, J G

    2014-04-01

    It is well known that unaccustomed eccentric exercise leads to muscle damage and soreness, which can produce long-lasting effects on muscle function. How this muscle damage influences muscle activation is poorly understood. The purpose of this brief review is to highlight the effect of eccentric exercise on the activation of muscle by the nervous system, by examining the change in motor unit activity obtained from surface electromyography (EMG) and intramuscular recordings. Previous research shows that eccentric exercise produces unusual changes in the EMG–force relation that influences motor performance during isometric, shortening and lengthening muscle contractions and during fatiguing tasks. When examining the effect of eccentric exercise at the single motor unit level, there are substantial changes in recruitment thresholds, discharge rates, motor unit conduction velocities and synchronization, which can last for up to 1 week after eccentric exercise. Examining the time course of these changes suggests that the increased submaximal EMG after eccentric exercise most likely occurs through a decrease in motor unit conduction velocity and an increase in motor unit activity related to antagonist muscle coactivation and low-frequency fatigue. Furthermore, there is a commonly held view that eccentric exercise produces preferential damage to high-threshold motor units, but the evidence for this in humans is limited. Further research is needed to establish whether there is preferential damage to high-threshold motor units after eccentric exercise in humans, preferably by linking changes in motor unit activity with estimates of motor unit size using selective intramuscular recording techniques.

  1. [An analysis of cost and profit of a nursing unit using performance-based costing: case of a general surgical ward in a general hospital].

    Science.gov (United States)

    Lim, Ji Young

    2008-02-01

    The aim of this study was to analyze net income of a surgical nursing ward in a general hospital. Data collection and analysis was conducted using a performance-based costing and activity-based costing method. Direct nursing activities in the surgical ward were 68, indirect nursing activities were 10. The total cost volume of the surgical ward was calculated at won 119,913,334.5. The cost volume of the allocated medical department was won 91,588,200.3, and the ward consumed cost was won 28,325,134.2. The revenue of the surgical nursing ward was won 33,269,925.0. The expense of a surgical nursing ward was 28,325,134.2. Therefore, the net income of a surgical nursing ward was won 4,944,790.8. We suggest that to develop a more refined nursing cost calculation model, a standard nursing cost calculation system needs to be developed.

  2. Multi-parameter vital sign database to assist in alarm optimization for general care units.

    Science.gov (United States)

    Welch, James; Kanter, Benjamin; Skora, Brooke; McCombie, Scott; Henry, Isaac; McCombie, Devin; Kennedy, Rosemary; Soller, Babs

    2016-12-01

    Continual vital sign assessment on the general care, medical-surgical floor is expected to provide early indication of patient deterioration and increase the effectiveness of rapid response teams. However, there is concern that continual, multi-parameter vital sign monitoring will produce alarm fatigue. The objective of this study was the development of a methodology to help care teams optimize alarm settings. An on-body wireless monitoring system was used to continually assess heart rate, respiratory rate, SpO2 and noninvasive blood pressure in the general ward of ten hospitals between April 1, 2014 and January 19, 2015. These data, 94,575 h for 3430 patients are contained in a large database, accessible with cloud computing tools. Simulation scenarios assessed the total alarm rate as a function of threshold and annunciation delay (s). The total alarm rate of ten alarms/patient/day predicted from the cloud-hosted database was the same as the total alarm rate for a 10 day evaluation (1550 h for 36 patients) in an independent hospital. Plots of vital sign distributions in the cloud-hosted database were similar to other large databases published by different authors. The cloud-hosted database can be used to run simulations for various alarm thresholds and annunciation delays to predict the total alarm burden experienced by nursing staff. This methodology might, in the future, be used to help reduce alarm fatigue without sacrificing the ability to continually monitor all vital signs.

  3. Cortico-thalamic activation in generalized status epilepticus, a PET study

    NARCIS (Netherlands)

    de Jong, B. M.; van de Hoeven, J. H.; Pruim, J.; van der Naalt, J.; Meertens, John H. J. M.

    2008-01-01

    In a patient with a refractory generalized convulsive status epilepticus, the ictal distribution of regional cerebral glucose was assessed with positron emission tomography (PET). Synchronized seizure activity in the EEG was associated with bilateral metabolic activation of medial sensorimotor regio

  4. A United Nations General Assembly Special Session for mental, neurological, and substance use disorders: the time has come.

    Science.gov (United States)

    Bass, Judith K; Bornemann, Thomas H; Burkey, Matthew; Chehil, Sonia; Chen, Lenis; Copeland, John R M; Eaton, William W; Ganju, Vijay; Hayward, Erin; Hock, Rebecca S; Kidwai, Rubeena; Kolappa, Kavitha; Lee, Patrick T; Minas, Harry; Or, Flora; Raviola, Giuseppe J; Saraceno, Benedetto; Patel, Vikram

    2012-01-01

    Mental, neurological, and substance use (MNS) disorders are leading causes of the global burden of disease and profoundly impact the social and economic well-being of individuals and communities. The majority of people affected by MNS disorders globally do not have access to evidence-based interventions and many experience discrimination and abuses of their human rights. A United Nations General Assembly Special Session (UNGASS) is needed to focus global attention on MNS disorders as a core development issue requiring commitments to improve access to care, promote human rights, and strengthen the evidence on effective prevention and treatment.

  5. Antibiotic prescription and cost patterns in a general intensive care unit

    Directory of Open Access Journals (Sweden)

    Krivoy N

    2007-06-01

    Full Text Available Antibiotic prescription habits, cost pattern, and the prospective intervention in an Intensive Care Unit were analyzed. Methods: Data on antibiotic utilization and costs were collected prospectively from individual electronic charts from August 2003 to January 2004, and retrospectively from August to December 2002. Results: A total of 180 and 107 patients were surveyed in 2002 and 2003. In 2002, Piperacillin-Tazobactam (13.8% and Imipenem/Cilastin (11.2% were the most prescribed medications; while, in 2003, Vancomycin (12.6% and Imipenem/Cilastin (11.3% were prescribed, respectively. Total defined daily dose (DDD and Drug Utilization 90% (DU90% index for 2002 and 2003 were 2031.15 and 2325.90 DDDs (p>0.1 and 1777.57 and 2079.61 DU90%, respectively (p>0.1. The Median Total Cost /100 admission days (CI 95% were NIS13,310 (11,110;18,420 and NIS13,860 (6,710;18,020 (p=0.66, respectively. Conclusions: Interventional programs should focus on promoting infectious control with rational antibiotic prescription aimed at minimizing the future emergence of bacterial resistance and futile expenses.

  6. Leveraging the Reserve Component: Associating Active and Reserve Aviation Units

    Science.gov (United States)

    2013-03-01

    capabilities, forces for large-scale conventional campaigns, balance stress across the Total Force, include a larger portion of American citizenry defending...Integration will also relieve stress on the Active Duty force and provide a cost-effective force multiplier. Finally, it will leverage the high...heavily.18 Other identified organizational challenges included cross- acculturation between active and reserve component career

  7. Patient profile and outcome of pilomatrixoma in district general hospital in United Kingdom

    Directory of Open Access Journals (Sweden)

    Mahmoud AbdelDayem

    2013-01-01

    Full Text Available Introduction: A pilomatrixoma is a benign appendage tumour related to hair cells matrix. Most of the literature review about pilomatrixoma is in the form of case reports with fewer cohort studies. The objective of this cohort is to study the variable demographic characteristics, presentation and histopathology of this condition among a larger group of patients. Materials and Methods: We conducted a retrospective study of patients who had excision of pilomatrixoma between February 1998 and August 2011 in a District General Hospital in UK. Results: The study included 67 patients with histopathologically diagnosed pilomatrixoma. The mean age was 32 years. Male to Female ratio was 35:32. The average diameter of the lesion at presentation was 13 mm (range: 2-30 mm. 66 of 67 (98.5% patients presented with solitary lesion, while 1 patient (1.5% had two lesions. Conclusion: Pilomatrixoma is not an uncommon benign lesion. It is more common in the maxillofacial area.

  8. Special Inspector General for Iraq Reconstruction. Quarterly Report and Semiannual Report to the United States Congress

    Science.gov (United States)

    2008-07-30

    Ongoing 12/26/2008 Salah Al-Din Water Reverse Feeding of Clean Water $10.18 Ongoing 1/8/2009 Basrah ABOT/KAAOT Oil Platform Life Support $9.71 Completed...defi cient in long-term planning, suffi cient reinte- gration assistance, and services needed to have a durable impact. Currently, returnee...ACTIVITY: • Outputs include seeds, beans, and potatoes, palm groves, citrus and other fruits, animals and poultry , and glass and ceramics

  9. Special Inspector General for Iraq Reconstruction Quarterly Report to the United States Congress

    Science.gov (United States)

    2012-04-30

    purchase feed-mill equipment, construction, and raw materials; the other to fi nance a new production line, expand inventory , and cover the cost of...supply, warehouse operations, inventory management, and security-assistance teams; contract logistics support activities for command, control, and...sale of Statoil’s 18.75% stake in the West Qurna-2 fi eld to the lead project operator Lukoil, which awarded South Korea’s Samsung a $1 billion, 31

  10. Active and Purely Dissipative Nambu Systems in General Thermostatistical Settings Described by Nonlinear Partial Differential Equations Involving Generalized Entropy Measures

    Directory of Open Access Journals (Sweden)

    T. D. Frank

    2016-12-01

    Full Text Available In physics, several attempts have been made to apply the concepts and tools of physics to the life sciences. In this context, a thermostatistic framework for active Nambu systems is proposed. The so-called free energy Fokker–Planck equation approach is used to describe stochastic aspects of active Nambu systems. Different thermostatistic settings are considered that are characterized by appropriately-defined entropy measures, such as the Boltzmann–Gibbs–Shannon entropy and the Tsallis entropy. In general, the free energy Fokker–Planck equations associated with these generalized entropy measures correspond to nonlinear partial differential equations. Irrespective of the entropy-related nonlinearities occurring in these nonlinear partial differential equations, it is shown that semi-analytical solutions for the stationary probability densities of the active Nambu systems can be obtained provided that the pumping mechanisms of the active systems assume the so-called canonical-dissipative form and depend explicitly only on Nambu invariants. Applications are presented both for purely-dissipative and for active systems illustrating that the proposed framework includes as a special case stochastic equilibrium systems.

  11. 78 FR 73863 - Public Availability of General Services Administration FY 2013 Federal Activities Inventory...

    Science.gov (United States)

    2013-12-09

    ... ADMINISTRATION Public Availability of General Services Administration FY 2013 Federal Activities Inventory Reform (FAIR) Act Inventory AGENCY: General Services Administration (GSA). ACTION: Notice of public... the Federal Activities Inventory Reform (FAIR) Act of 1998, Public Law 105-270, and Office...

  12. Planning Development for a Family Planning Centre in Nursing Unit of the General Hospital of Argolida

    Directory of Open Access Journals (Sweden)

    Koukoufilippou J

    2015-01-01

    Full Text Available Introduction: The family planning centres must be upgraded to a cornerstone of primary health care, and prevent, advise and protect the citizen's health while reducing hospitalization costs for hospitals. Aim: The purpose of this literature review is the family planning centre development in general hospital of Argolida that has a similar clinic. Material and Methods: Literature review was conducted of published English and Greek Articles from bibliographic databases Medline, Google Scholar and Scopus for the period 2001-2014, using keywords like: "Family Planning», «SWOT analysis", "functional design" "prevention", "health promotion", "economic cost". The option of creating inpatient center was made after analysis SWOT, by defining objectives, performance indicators and existing alternatives. Also the timing of implementation and functional design, provide the springboard effort for effective operation. Conclusions: The development of family planning centres in the country and abroad is designed to address very important problems in the bud, in order to improve the quality of citizens' health, then reduce the financial burden on the health system as a result of prevention, and contribute indirectly to the mental balance of citizens.

  13. Child and Adolescent Inpatient Unit in General Hospital “Tzaneio”

    Directory of Open Access Journals (Sweden)

    E. Tseva

    2017-01-01

    Full Text Available The Child and Adolescent Psychiatry Inpatient Service offers comprehensive diagnostic evaluation and treatment of children and adolescents (typical age ranges from 3-16 years old with a variety of emotional and behavioral problems including mood disorders, anxiety disorders, psychotic disorders, severe disruptive behavior, and suicide attempts. Treatment Team. The inpatient treatment team includes psychiatrists, psychologists, registered nurses, special education teacher, social worker, speech and occupational therapists. In addition, pediatricians from a full range of medical subspecialties are available for consultations. The multi-disciplinary staff emphasizes a family-oriented approach and parents and care-givers are encouraged to be active participants in the treatment team throughout a child’s stay. Treatment Program. The program offers developmentally appropriate therapeutic activities in a closely supervised environment. Extensive opportunities for observation, assessment, and intervention are possible in this intensive setting. Specialized assessments including neuropsychological testing, speech and language testing, and occupational therapy assessments are all available. Treatment plans typically include a combination of individual psychotherapy, behavior management, family counseling and medications. Staff members develop an individualized treatment plan emphasizing safety for each patient during the hospital stay. The plan is closely coordinated with families, outpatient providers, and resource programs to coordinate aftercare plans and facilitate a smooth transition to home.

  14. Surgical management of pneumothorax: significance of effective admission or communication strategies between the district general hospitals and specialized unit.

    Science.gov (United States)

    Aslam, Muhammad I; Martin-Ucar, Antonio E; Nakas, Apostolos; Waller, David A

    2011-11-01

    A preoperative delay in emergency surgery for spontaneous pneumothorax is associated with a poor outcome after surgery and a prolonged hospital stay. To reduce preoperative delays, all tertiary referrals from district general hospitals to our thoracic surgery unit were processed through a 'clinical decisions unit' (CDU). Prior to the establishment of the CDU, these patients were added to a waiting list for a surgical bed. This study has reviewed the effect of this change in admission policy on the efficiency of treatment for non-elective spontaneous pneumothorax. An intergroup comparison (pre-CDU group vs. post-CDU group) was made of the following parameters: referral to transfer time, transfer to surgery time and length of inpatient stay in the referring and tertiary hospitals. There were no significant differences in gender, diagnosis, treatment in the referring hospitals, postoperative clinical outcome, or indications for or type of surgery. The total length of inpatient stay in the referring and tertiary hospitals was significantly reduced for the post-CDU group (12 vs. 15 days; P<0.001), which was attributed to the earlier transfer of patients (18 vs. 78 hours; P<0.001) hours. Allowing surgical access to a traditional medical admission unit is therefore, cost-effective and significantly improves the efficiency of non-elective pneumothorax surgery.

  15. A review of recent activity in the United States.

    Science.gov (United States)

    Cannon, H.L.; Petrie, W.L.

    1979-01-01

    Either an overabundance or a deficiency of trace metals in the food chain can ultimately affect adversely the health of livestock and man. Increasing interest in the United States in the distribution of metals in the environment and in metal pollutants has led to widespread interdisciplinary research sponsored by governmental, private and academic groups concerning the availability of trace elements for absorption by plants and animals, and the effects of trace elements throughout the food chain. Effects on the environment of coal-fired power plants, the mining and processing of metals, asbestos, and phosphate, and the disposal of industrial and nuclear wastes have also received much attention in the past few years.-Authors

  16. Recognition of the noise sources and measurement in educational hospital s General Intensive Care Unit (GICU

    Directory of Open Access Journals (Sweden)

    Vahideh Abolhasannejad

    2014-11-01

    Results: Mean sound pressure level for GICU was 60.9±1/6 dBA that is more than the standard level. The mean of maximum noise level was obtained 82.5±2 dBA and the highest noise level was measured at nursing station. There was significant difference in Noise Pollution level based on different months, level of patient's conciseness and number of ventilator using (P < 0.05. Conclusion: Being more noise pollution in the ICU and stations on all shifts may cause to diminish health and well-being of the staff in long-term and produce some problems for the patient. According to the highest level of noise produced in nursing stations and the different activities doing by the staff as a main noise pollution factor, it's necessary to perform required training in relationship with doing the works in right manner so that we can produce quiet and silence environment for patience.

  17. Volume of activity and occupancy rate in intensive care units. Association with mortality

    NARCIS (Netherlands)

    Iapichino, G; Gattinoni, L; Radrizzani, D; Simini, B; Bertolini, G; Ferla, L; Mistraletti, G; Porta, F; Miranda, DR

    Objective. Mortality after many procedures is lower in centers where more procedures are done. It is controversial whether this is true for intensive care units, too. We examined the relationship between the volume of activity of intensive care units (ICUs) and mortality by a measure of

  18. [Motor unit activities of human masseter muscle during sustained voluntary contractions].

    Science.gov (United States)

    Shimizu, T

    1990-02-01

    The purpose of this paper is to investigate the motor unit activities of the human masseter muscle during sustained the bite force at a constant level. The electrical activities recorded with surface and inserted electrodes were studied, with the following results. 1. The masseter muscle had the changes of activities in two phases as a contraction progressed. 2. In the first phase, surface EMG activities decreased and discharge frequency of motor units also decreased. 3. In the second phase, surface EMG activities increased and discharge frequency of motor units also increased. 4. In the first phase, it was suggested that the bite force was maintained by an increase in the twitch tension produced by a motor unit and that there were no recruitment of additional motor units. 5. In the second phase, it was indicated that the bite force was maintained by the recruitment of new motor units and an increase in the discharge frequency of motor units to compensate a loss of force resulted from the contractile element fatigue.

  19. United States-Russia: Environmental management activities, Summer 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-09-01

    A Joint Coordinating Committee for Environmental Restoration and Waste Management (JCCEM) was formed between the US and Russia. This report describes the areas of research being studied under JCCEM, namely: Efficient separations; Contaminant transport and site characterization; Mixed wastes; High level waste tank remediation; Transuranic stabilization; Decontamination and decommissioning; and Emergency response. Other sections describe: Administrative framework for cooperation; Scientist exchange; Future actions; Non-JCCEM DOE-Russian activities; and JCCEM publications.

  20. Effects of Methamphetamine on Single Unit Activity in Rat Medial Prefrontal Cortex In Vivo

    Directory of Open Access Journals (Sweden)

    Jinhwa Jang

    2007-01-01

    Full Text Available To investigate how neuronal activity in the prefrontal cortex changes in an animal model of schizophrenia, we recorded single unit activity in the medial prefrontal cortex of urethane-anesthetized and awake rats following methamphetamine (MA administration. Systemic MA injection (4 mg/kg, IP induced inconsistent changes, that is, both enhancement and reduction, in unit discharge rate, with a subset of neurons transiently (<30 min elevating their activities. The direction of firing rate change was poorly predicted by the mean firing rate or the degree of burst firing during the baseline period. Also, simultaneously recorded units showed opposite directions of firing rate change, indicating that recording location is a poor predictor of the direction of firing rate change. These results raise the possibility that systemic MA injection induces random bidirectional changes in prefrontal cortical unit activity, which may underlie some of MA-induced psychotic symptoms.

  1. Physical Activity Patterns of Acute Stroke Patients Managed in a Rehabilitation Focused Stroke Unit

    Directory of Open Access Journals (Sweden)

    Tanya West

    2013-01-01

    Full Text Available Background. Comprehensive stroke unit care, incorporating acute care and rehabilitation, may promote early physical activity after stroke. However, previous information regarding physical activity specific to the acute phase of stroke and the comprehensive stroke unit setting is limited to one stroke unit. This study describes the physical activity undertaken by patients within 14 days after stroke admitted to a comprehensive stroke unit. Methods. This study was a prospective observational study. Behavioural mapping was used to determine the proportion of the day spent in different activities. Therapist reports were used to determine the amount of formal therapy received on the day of observation. The timing of commencement of activity out of bed was obtained from the medical records. Results. On average, patients spent 45% (SD 25 of the day in some form of physical activity and received 58 (SD 34 minutes per day of physiotherapy and occupational therapy combined. Mean time to first mobilisation out of bed was 46 (SD 32 hours post-stroke. Conclusions. This study suggests that commencement of physical activity occurs earlier and physical activity is at a higher level early after stroke in this comprehensive stroke unit, when compared to studies of other acute stroke models of care.

  2. Use of Flumazenil to Provide Adequate Recovery Time Post-Midazolom Infusion in a General Intensive Care Unit

    Directory of Open Access Journals (Sweden)

    MOJTABA MOJTAHEDZADEH

    1999-08-01

    Full Text Available Sedation permits patients to tolerate the various treatment modalities to which they are subjected. However it may sometimes cause prolonged sedation in critically ill patients. Flumazenil, a benzo¬diazepine antagonist, reverses midazolam-induced sedation and amnesia. We prospectively designed a double-blind randomized study to evaluate the effects of flumazenil on thirty (30 Iranian General Intensive Care Unit (ICU patients. They were requiring mechanical ventilation for more than 12 hours and they were sedated by midazolam infusions. Sedation levels were measured hourly during the infusion, at the end of the infusion, and at 5, 15, 30, 60, and 120 min after cessation of the mida¬zolam infusion. Reversal of sedation was observed in all patients who received flumazenil, and re-sedation occurred in seven of these patients. Reversal was not seen in any of the patients who receiv-ed placebo.

  3. Intrinsic activation of human motoneurons: possible contribution to motor unit excitation.

    Science.gov (United States)

    Gorassini, Monica; Yang, Jaynie F; Siu, Merek; Bennett, David J

    2002-04-01

    The main purpose of this study was to estimate the contribution of intrinsic activation of human motoneurons (e.g., by plateau potentials) during voluntary and reflexive muscle contractions. Pairs of motor units were recorded from either the tibialis anterior or soleus muscle during three different conditions: 1) during a brief muscle vibration followed by a slow relaxation of a steady isometric contraction; 2) during a triangular isometric torque contraction; and 3) during passive sinusoidal muscle stretch superimposed on a steady isometric contraction. In each case, the firing rate of a tonically firing control motor unit was used as a measure of the effective synaptic excitation (i.e., synaptic drive) to a slightly higher-threshold test motor unit that was recruited and de-recruited during a contraction trial. The firing rate of the control unit was compared at recruitment and de-recruitment of the test unit. This was done to determine whether the estimated synaptic drive needed to recruit a motor unit was less than the amount needed to sustain firing as a result of an added depolarization produced from intrinsic sources. After test unit recruitment, the firing rate of the control unit could be decreased significantly (on average by 3.6 Hz from an initial recruitment rate of 9.8 Hz) before the test unit was de-recruited during a descending synaptic drive. Similar decreases in control unit rate occurred in all three experimental conditions. This represents a possible 40% reduction in the estimated synaptic drive needed to maintain firing of a motor unit compared with the estimated amount needed to recruit the unit initially. The firing rates of both the control and test units were modulated together in a highly parallel fashion, suggesting that the unit pairs were driven by common synaptic inputs. This tight correlation further validated the use of the control unit firing rate as a monitor of synaptic drive to the test motor unit. The estimates of intrinsically

  4. Risk factors associated with calcium oxalate urolithiasis in dogs evaluated at general care veterinary hospitals in the United States.

    Science.gov (United States)

    Okafor, Chika C; Lefebvre, Sandra L; Pearl, David L; Yang, Mingyin; Wang, Mansen; Blois, Shauna L; Lund, Elizabeth M; Dewey, Cate E

    2014-08-01

    Calcium oxalate urolithiasis results from the formation of aggregates of calcium salts in the urinary tract. Difficulties associated with effectively treating calcium oxalate urolithiasis and the proportional increase in the prevalence of calcium oxalate uroliths relative to other urolith types over the last 2 decades has increased the concern of clinicians about this disease. To determine factors associated with the development of calcium oxalate urolithiasis in dogs evaluated at general care veterinary hospitals in the United States, a retrospective case-control study was performed. A national electronic database of medical records of all dogs evaluated between October 1, 2007 and December 31, 2010 at 787 general care veterinary hospitals in the United States was reviewed. Dogs were selected as cases at the first-time diagnosis of a laboratory-confirmed urolith comprised of at least 70% calcium oxalate (n=452). Two sets of control dogs with no history of urolithiasis diagnosis were randomly selected after the medical records of all remaining dogs were reviewed: urinalysis examination was a requirement in the selection of one set (n=1808) but was not required in the other set (n=1808). Historical information extracted included urolith composition, dog's diet, age, sex, neuter status, breed size category, hospital location, date of diagnosis, and urinalysis results. Multivariable analysis showed that the odds of first-time diagnosis of calcium oxalate urolithiasis were significantly (P30 mg/dL (OR: 1.55, 1.04-2.30). Patient demographics and urinalysis results are important factors that can support risk assessment and early identification of canine oxalate urolithiasis. Therefore, periodic urolith screening and monitoring of urine parameters should be encouraged for dogs at risk of developing these uroliths.

  5. Functional recovery of elderly patients hospitalized in geriatric and general medicine units. The PROgetto DImissioni in GEriatria Study.

    Science.gov (United States)

    Palleschi, Lorenzo; De Alfieri, Walter; Salani, Bernardo; Fimognari, Filippo Luca; Marsilii, Alberto; Pierantozzi, Andrea; Di Cioccio, Luigi; Zuccaro, Stefano Maria

    2011-02-01

    To investigate the characteristics of patients who regain function during hospitalization and the differences in terms of functional outcomes between patients admitted to geriatric and general medicine units. Multicenter, prospective cohort study. Acute care geriatric and medical wards of five Italian hospitals. One thousand forty-eight elderly patients hospitalized for acute medical diseases. Functional status 2 weeks before hospital admission (baseline), at admission, and at discharge, as measured using the Barthel Index (BI). Geriatric patients were older (P<.001) and had lower preadmission functional levels (P<.001) than medical patients. Between baseline and discharge, 43.2% of geriatric and 18.9% of medical patients declined in physical function. In the subpopulation of 464 patients who had declined before hospitalization (between baseline and admission), 59% improved during hospitalization (45% of geriatric and 75% of medical patients), whereas only approximately 1% declined further. High baseline function (odds ratio (OR)=1.03, 95% confidence interval (CI)=1.02-1.04, per point of BI) and greater functional decline before hospitalization (OR 0.95, 95% CI 0.94-0.97, per % point of BI decline) were significant predictors of in-hospital functional improvement; type of hospital ward and age were not. Although geriatric patients have overall worse functional outcomes, in-hospital functional recovery may be frequent even in geriatric units, particularly in patients with greater preadmission functional loss and high baseline level of function. © 2011, Copyright the Authors. Journal compilation © 2011, The American Geriatrics Society.

  6. Activation process in excitable systems with multiple noise sources: Large number of units

    CERN Document Server

    Franović, Igor; Todorović, Kristina; Kostić, Srđan; Burić, Nikola

    2015-01-01

    We study the activation process in large assemblies of type II excitable units whose dynamics is influenced by two independent noise terms. The mean-field approach is applied to explicitly demonstrate that the assembly of excitable units can itself exhibit macroscopic excitable behavior. In order to facilitate the comparison between the excitable dynamics of a single unit and an assembly, we introduce three distinct formulations of the assembly activation event. Each formulation treats different aspects of the relevant phenomena, including the threshold-like behavior and the role of coherence of individual spikes. Statistical properties of the assembly activation process, such as the mean time-to-first pulse and the associated coefficient of variation, are found to be qualitatively analogous for all three formulations, as well as to resemble the results for a single unit. These analogies are shown to derive from the fact that global variables undergo a stochastic bifurcation from the stochastically stable fix...

  7. Single motor unit activity in human extraocular muscles during the vestibulo-ocular reflex.

    Science.gov (United States)

    Weber, Konrad P; Rosengren, Sally M; Michels, Rike; Sturm, Veit; Straumann, Dominik; Landau, Klara

    2012-07-01

    Motor unit activity in human eye muscles during the vestibulo-ocular reflex (VOR) is not well understood, since the associated head and eye movements normally preclude single unit recordings. Therefore we recorded single motor unit activity following bursts of skull vibration and sound, two vestibular otolith stimuli that elicit only small head and eye movements. Inferior oblique (IO) and inferior rectus (IR) muscle activity was measured in healthy humans with concentric needle electrodes. Vibration elicited highly synchronous, short-latency bursts of motor unit activity in the IO (latency: 10.5 ms) and IR (14.5 ms) muscles. The activation patterns of the two muscles were similar, but reciprocal, with delayed activation of the IR muscle. Sound produced short-latency excitation of the IO muscle (13.3 ms) in the eye contralateral to the stimulus. Simultaneous needle and surface recordings identified the IO as the muscle of origin of the vestibular evoked myogenic potential (oVEMP) thus validating the physiological basis of this recently developed clinical test of otolith function. Single extraocular motor unit recordings provide a window into neural activity in humans that can normally only be examined using animal models and help identify the pathways of the translational VOR from otoliths to individual eye muscles.

  8. 40 CFR 60.1370 - What records must I keep for municipal waste combustion units that use activated carbon?

    Science.gov (United States)

    2010-07-01

    ... waste combustion units that use activated carbon? 60.1370 Section 60.1370 Protection of Environment... Recordkeeping § 60.1370 What records must I keep for municipal waste combustion units that use activated carbon? For municipal waste combustion units that use activated carbon to control dioxins/furans or...

  9. 40 CFR 60.1855 - What records must I keep for municipal waste combustion units that use activated carbon?

    Science.gov (United States)

    2010-07-01

    ... waste combustion units that use activated carbon? 60.1855 Section 60.1855 Protection of Environment... waste combustion units that use activated carbon? For municipal waste combustion units that use activated carbon to control dioxins/furans or mercury emissions, you must keep records of five items:...

  10. 40 CFR 62.15310 - What records must I keep for municipal waste combustion units that use activated carbon?

    Science.gov (United States)

    2010-07-01

    ... waste combustion units that use activated carbon? 62.15310 Section 62.15310 Protection of Environment... for municipal waste combustion units that use activated carbon? For municipal waste combustion units that use activated carbon to control dioxins/furans or mercury emissions, you must keep records of...

  11. 77 FR 23322 - Proposed Information Collection (Report of General Information) Activity: Comment Request

    Science.gov (United States)

    2012-04-18

    ... AFFAIRS Proposed Information Collection (Report of General Information) Activity: Comment Request AGENCY... comment on the proposed collection of certain information by the agency. Under the Paperwork Reduction Act... proposed collection of information, including each proposed extension of a currently approved...

  12. IMPROVEMENT OF ECONOMIC COMPETENCE OF HEADS OF SECONDARY EDUCATION FOR EFFECTIVE ACTIVITY OF GENERAL SCHOOLS

    Directory of Open Access Journals (Sweden)

    Volodymyr V. Dyvak

    2010-08-01

    Full Text Available In the article the actual problem of improvement of economic competence of professional work of directors of schools for more efficient control of activity of general schools is considered.

  13. 77 FR 10752 - Agency Information Collection Activities; Proposed Collection; Comment Request; General Licensing...

    Science.gov (United States)

    2012-02-23

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration Agency Information Collection Activities; Proposed Collection; Comment Request; General Licensing Provisions; Section 351(k) Biosimilar Applications;...

  14. 78 FR 48647 - Foreign-Trade Zone 225-Springfield, Missouri; Authorization of Production Activity; General...

    Science.gov (United States)

    2013-08-09

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Foreign-Trade Zones Board Foreign-Trade Zone 225--Springfield, Missouri; Authorization of Production Activity; General Dynamics Ordnance and Tactical Systems Munitions Services (Demilitarization of...

  15. 77 FR 54917 - Public Availability of General Services Administration FY 2012 Federal Activities Inventory...

    Science.gov (United States)

    2012-09-06

    ... ADMINISTRATION Public Availability of General Services Administration FY 2012 Federal Activities Inventory Reform (FAIR) Act Inventory AGENCY: General Services Administration (GSA). ACTION: Notice of Public... accordance with the FAIR Act of 1998, Public Law 105-270, and Office of Management and Budget (OMB)...

  16. Multi­-Threaded Algorithms for General purpose Graphics Processor Units in the ATLAS High Level Trigger

    CERN Document Server

    Conde Mui\\~no, Patricia; The ATLAS collaboration

    2016-01-01

    General purpose Graphics Processor Units (GPGPU) are being evaluated for possible future inclusion in an upgraded ATLAS High Level Trigger farm. We have developed a demonstrator including GPGPU implementations of Inner Detector and Muon tracking and Calorimeter clustering within the ATLAS software framework. ATLAS is a general purpose particle physics experiment located on the LHC collider at CERN. The ATLAS Trigger system consists of two levels, with level 1 implemented in hardware and the High Level Trigger implemented in software running on a farm of commodity CPU. The High Level Trigger reduces the trigger rate from the 100 kHz level 1 acceptance rate to 1 kHz for recording, requiring an average per­-event processing time of ~250 ms for this task. The selection in the high level trigger is based on reconstructing tracks in the Inner Detector and Muon Spectrometer and clusters of energy deposited in the Calorimeter. Performing this reconstruction within the available farm resources presents a significant ...

  17. The Relationship between Physical Activity and General Health among Menopausal Women in Ahvaz, Iran.

    Science.gov (United States)

    Sharifi, Nasibeh; Jalili, Lida; Khazaeian, Somayeh; Nia, Anvar-Sadat Nayebi

    2017-01-01

    Most women experience significant changes in their general health status during menopause, which negatively affects their quality of life. Physical activity has also been shown to enhance quality of life. However, little is known about the effect of physical activity on women's health during the menopausal transition. This study aimed to determine the relationship between physical activity and general health among menopausal women in Ahvaz, Iran. This cross sectional study was carried out on 600 menopausal women using cluster random sampling during 2013-2014. Data collection tools were three questionnaires; women's demographic characteristics, the Goldenberg's questionnaire, and International physical activity questionnaire (IPAQ). Data were analyzed using descriptive and inferential statistics through SPSS version 19. The statistical tests were performed at the 95% confidence interval. There was a significant relationship between the total score of physical activity and physical health, social functioning, anxiety and depression (prelationship was found between subscales related to physical activity and general health (p>0.05). Physical activity is effective in improving general health in menopausal women. Proper training and effective interventions for regular physical activity can be important steps to promote the general health of menopausal women.

  18. Rectification of SEMG as a tool to demonstrate synchronous motor unit activity during vibration.

    Science.gov (United States)

    Sebik, Oguz; Karacan, Ilhan; Cidem, Muharrem; Türker, Kemal S

    2013-04-01

    The use of surface electromyography (SEMG) in vibration studies is problematic since motion artifacts occupy the same frequency band with the SEMG signal containing information on synchronous motor unit activity. We hypothesize that using a harsher, 80-500 Hz band-pass filter and using rectification can help eliminate motion artifacts and provide a way to observe synchronous motor unit activity that is phase locked to vibration using SEMG recordings only. Multi Motor Unit (MMU) action potentials using intramuscular electrodes along with SEMG were recorded from the gastrocnemius medialis (GM) of six healthy male volunteers. Data were collected during whole body vibration, using vibration frequencies of 30 Hz, 35 Hz, 40 Hz or 50 Hz. A computer simulation was used to investigate the efficacy of filtering under different scenarios: with or without artifacts and/or motor unit synchronization. Our findings indicate that motor unit synchronization took place during WBV as verified by MMU recordings. A harsh filtering regimen along with rectification proved successful in demonstrating motor unit synchronization in SEMG recordings. Our findings were further supported by the results from the computer simulation, which indicated that filtering and rectification was efficient in discriminating motion artifacts from motor unit synchronization. We suggest that the proposed signal processing technique may provide a new methodology to evaluate the effects of vibration treatments using only SEMG. This is a major advantage, as this non-intrusive method is able to overcome movement artifacts and also indicate the synchronization of underlying motor units.

  19. 30 CFR 250.201 - What plans and information must I submit before I conduct any activities on my lease or unit?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What plans and information must I submit before I conduct any activities on my lease or unit? 250.201 Section 250.201 Mineral Resources MINERALS... CONTINENTAL SHELF Plans and Information General Information § 250.201 What plans and information must I...

  20. The practice of active rest by workplace units improves personal relationships, mental health, and physical activity among workers

    OpenAIRE

    Michishita, Ryoma; Jiang, Ying; Ariyoshi, Daisuke; Yoshida, Marie; Moriyama, Hideko; Yamato, Hiroshi

    2016-01-01

    Aim: This study was designed to clarify the effects of active rest, with a focus on the practice of short-time group exercise by workplace units, on personal relationships, mental health, physical activity, and work ability among workers. Methods: Fifty-nine white-collar workers (40 males and 19 females) performed our active rest (short-time exercise) program, which consists of warm-up, cognitive functional training, aerobic exercise, resistance training and cool-down for 10 minutes per day, ...

  1. It isn't all just fun and games: Collegiate participation in extracurricular activities and risk for generalized and sexual harassment, psychological distress, and alcohol use.

    Science.gov (United States)

    McGinley, Meredith; Rospenda, Kathleen M; Liu, Li; Richman, Judith A

    2016-12-01

    Collegiate extracurricular activities, despite their benefits, may place students at an increased risk for experiencing harassment. This study utilizes multiple waves of data from an online longitudinal survey to examine how participation in college activities (intramural sports, fraternities/sororities, school clubs) relates to experiences of sexual and generalized harassment and outcomes (psychological distress, heavy alcohol use) among undergraduates (N = 1852, 58.6% female, 57.4% White) in the Midwestern United States. Activity participation was related to harassment, but the pattern depended on the activity, harassment type, and sex. Fraternity/sorority involvement was associated with generalized harassment, whereas school club involvement was linked to both generalized and sexual harassment. Female intramural athletes were at an increased risk to experience both harassment types. In addition to direct relations, activity participation was indirectly linked to future psychological distress (depression, anxiety) and heavy alcohol use via harassment. Implications for intervention with this college student population are discussed.

  2. Natural Environments, Obesity, and Physical Activity in Nonmetropolitan Areas of the United States

    Science.gov (United States)

    Michimi, Akihiko; Wimberly, Michael C.

    2012-01-01

    Purpose: To assess the associations of the natural environment with obesity and physical activity in nonmetropolitan areas of the United States among representative samples by using 2 indices of outdoor activity potential (OAP) at the county level. Methods: We used the data from 457,820 and 473,296 noninstitutionalized adults aged over 18 years…

  3. Report of Activity, 1996 - 1997. Vol. 3. General activities - Technical Research; Rapport d`activite 1996 - 1997. Tome 3. Activites generales - Recherches techniques

    Energy Technology Data Exchange (ETDEWEB)

    Pouthas, Joel; Hutin, Christiane; Niogret Mathias [eds.] [Inst. de Physique Nucleaire, Paris-11 Univ., 91 - Orsay (France)

    1999-11-01

    This is the third tome of the Report of Activity of IPN - Orsay on 1996-1997. It deals with general activities and technical research. Summary reports and short communications are grouped in the following sections: 1 - Accelerators with the sub-divisions 1.1 - R and D on superconducting RF cavities; 1.2 - SPIRAL Project; 1.3 - Contribution to the LHC Project; 1.4 - Tandem; 2 - Targets, Sources and Injectors; 3 - Detectors and related instrumentation; 4 - Electronics; 5 - Data processing; 6 - Radioprotection and medical applications

  4. Activity of the anterior cingulate cortex and ventral hippocampus underlie increases in contextual fear generalization.

    Science.gov (United States)

    Cullen, Patrick K; Gilman, T Lee; Winiecki, Patrick; Riccio, David C; Jasnow, Aaron M

    2015-10-01

    Memories for context become less specific with time resulting in animals generalizing fear from training contexts to novel contexts. Though much attention has been given to the neural structures that underlie the long-term consolidation of a context fear memory, very little is known about the mechanisms responsible for the increase in fear generalization that occurs as the memory ages. Here, we examine the neural pattern of activation underlying the expression of a generalized context fear memory in male C57BL/6J mice. Animals were context fear conditioned and tested for fear in either the training context or a novel context at recent and remote time points. Animals were sacrificed and fluorescent in situ hybridization was performed to assay neural activation. Our results demonstrate activity of the prelimbic, infralimbic, and anterior cingulate (ACC) cortices as well as the ventral hippocampus (vHPC) underlie expression of a generalized fear memory. To verify the involvement of the ACC and vHPC in the expression of a generalized fear memory, animals were context fear conditioned and infused with 4% lidocaine into the ACC, dHPC, or vHPC prior to retrieval to temporarily inactivate these structures. The results demonstrate that activity of the ACC and vHPC is required for the expression of a generalized fear memory, as inactivation of these regions returned the memory to a contextually precise form. Current theories of time-dependent generalization of contextual memories do not predict involvement of the vHPC. Our data suggest a novel role of this region in generalized memory, which should be incorporated into current theories of time-dependent memory generalization. We also show that the dorsal hippocampus plays a prolonged role in contextually precise memories. Our findings suggest a possible interaction between the ACC and vHPC controls the expression of fear generalization.

  5. Are formalised implementation activities associated with aspects of quality of care in general practice?

    DEFF Research Database (Denmark)

    Videbæk Le, Jette; Pedersen, Line Bjørnskov; Riisgaard, Helle

    2017-01-01

    Background There is a substantial variation in how different general practices manage knowledge implementation, including the degree to which activities are collectively and formally organised. Yet, it is unclear how these differences in implementation activities affect quality of care. Aim To in...

  6. The practice of active rest by workplace units improves personal relationships, mental health, and physical activity among workers.

    Science.gov (United States)

    Michishita, Ryoma; Jiang, Ying; Ariyoshi, Daisuke; Yoshida, Marie; Moriyama, Hideko; Yamato, Hiroshi

    2017-03-28

    This study was designed to clarify the effects of active rest, with a focus on the practice of short-time group exercise by workplace units, on personal relationships, mental health, physical activity, and work ability among workers. Fifty-nine white-collar workers (40 males and 19 females) performed our active rest (short-time exercise) program, which consists of warm-up, cognitive functional training, aerobic exercise, resistance training and cool-down for 10 minutes per day, 3 times per week during their lunch breaks for 10 weeks. Participants from a workplace unit were randomly allocated to the intervention (five workplaces, n=29) or control groups (six workplaces, n=30). The participants' anthropometric measurements, and their Profile of Mood States (POMS) 2, Brief Job Stress Questionnaire (BJSQ), physical activity levels and Work Ability Index were examined at the baseline and after the 10-week intervention. After 10 weeks, physical activity levels, especially the time spent in moderate and vigorous intensity, increased in the intervention group (pchange in "vigor-activity" in POMS 2 (r=0.467, p=0.011). These results suggest that the practice of active rest by workplace units is important for improving personal relationships, mental health, and physical activity among workers.

  7. Economic Evaluation of a General Hospital Unit for Older People with Delirium and Dementia (TEAM Randomised Controlled Trial.

    Directory of Open Access Journals (Sweden)

    Lukasz Tanajewski

    Full Text Available One in three hospital acute medical admissions is of an older person with cognitive impairment. Their outcomes are poor and the quality of their care in hospital has been criticised. A specialist unit to care for older people with delirium and dementia (the Medical and Mental Health Unit, MMHU was developed and then tested in a randomised controlled trial where it delivered significantly higher quality of, and satisfaction with, care, but no significant benefits in terms of health status outcomes at three months.To examine the cost-effectiveness of the MMHU for older people with delirium and dementia in general hospitals, compared with standard care.Six hundred participants aged over 65 admitted for acute medical care, identified on admission as cognitively impaired, were randomised to the MMHU or to standard care on acute geriatric or general medical wards. Cost per quality adjusted life year (QALY gained, at 3-month follow-up, was assessed in trial-based economic evaluation (599/600 participants, intervention: 309. Multiple imputation and complete-case sample analyses were employed to deal with missing QALY data (55%.The total adjusted health and social care costs, including direct costs of the intervention, at 3 months was £7714 and £7862 for MMHU and standard care groups, respectively (difference -£149 (95% confidence interval [CI]: -298, 4. The difference in QALYs gained was 0.001 (95% CI: -0.006, 0.008. The probability that the intervention was dominant was 58%, and the probability that it was cost-saving with QALY loss was 39%. At £20,000/QALY threshold, the probability of cost-effectiveness was 94%, falling to 59% when cost-saving QALY loss cases were excluded.The MMHU was strongly cost-effective using usual criteria, although considerably less so when the less acceptable situation with QALY loss and cost savings were excluded. Nevertheless, this model of care is worthy of further evaluation.ClinicalTrials.gov NCT01136148.

  8. On hydrologic similarity: A dimensionless flood frequency model using a generalized geomorphologic unit hydrograph and partial area runoff generation

    Science.gov (United States)

    Sivapalan, Murugesu; Wood, Eric F.; Beven, Keith J.

    1993-01-01

    One of the shortcomings of the original theory of the geomorphologic unit hydrograph (GUH) is that it assumes that runoff is generated uniformly from the entire catchment area. It is now recognized that in many catchments much of the runoff during storm events is produced on partial areas which usually form on narrow bands along the stream network. A storm response model that includes runoff generation on partial areas by both Hortonian and Dunne mechanisms was recently developed by the authors. In this paper a methodology for integrating this partial area runoff generation model with the GUH-based runoff routing model is presented; this leads to a generalized GUH. The generalized GUH and the storm response model are then used to estimate physically based flood frequency distributions. In most previous work the initial moisture state of the catchment had been assumed to be constant for all the storms. In this paper we relax this assumption and allow the initial moisture conditions to vary between storms. The resulting flood frequency distributions are cast in a scaled dimensionless framework where issues such as catchment scale and similarity can be conveniently addressed. A number of experiments are performed to study the sensitivity of the flood frequency response to some of the 'similarity' parameters identified in this formulation. The results indicate that one of the most important components of the derived flood frequency model relates to the specification of processes within the runoff generation model; specifically the inclusion of both saturation excess and Horton infiltration excess runoff production mechanisms. The dominance of these mechanisms over different return periods of the flood frequency distribution can significantly affect the distributional shape and confidence limits about the distribution. Comparisons with observed flood distributions seem to indicate that such mixed runoff production mechanisms influence flood distribution shape. The

  9. The epidemiological profile of pediatric patients admitted to the general intensive care unit in an Ethiopian university hospital

    Directory of Open Access Journals (Sweden)

    Abebe T

    2015-01-01

    Full Text Available Teshome Abebe, Mullu Girmay, Girma G/Michael, Million Tesfaye Department of Anesthesia, Jimma University, Jimma, Ethiopia Background: In least developing countries, there are few data on children's critical care. This makes the provision of aid and improvement of outcome difficult. Objectives: To describe admission and outcome patterns of children managed in a general intensive care unit at Jimma University Specialized Hospital (JUSH, Ethiopia, over a 5-year period. Methods: A retrospective cross-sectional study design was used. All children from birth to 14 years of age who were admitted to the general ICU of the hospital from 2009–2013 were included. Patient charts and ICU documentation log were reviewed. Results: A total of 170 children were admitted to the ICU of JUSH over the study period. The greater share was taken by males (54.7%, with a male-to-female ratio of 1.2:1. The overall mortality rate was 40%. The majority of the children were in the age range of 10–14 years (38.8%. Of the total number of patients admitted, 34.7% were trauma cases, 45.8% of whom died. The highest percentage, 69.5%, of trauma patients were admitted for head injuries. Among the trauma cases, burn and polytrauma were the second and third leading causes (15.3% of admission. Postoperative patients and medical patients accounted for the rest of the admitted cases (28.2% and 27.6% of the cases respectively. Conclusion: The leading cause of admission and death was trauma. Postoperative and medical causes of admission were also significant. The mortality rate in the ICU was very high, and this could be due to various factors. Further research benchmarking and interventions are highly recommended. Keywords: trauma, critical care, pediatric, ICU, ventilation, oxygenation

  10. The United Nations Human Space Technology Initiative (HSTI): Activity Status in 2012

    CERN Document Server

    Ochiai, M; Haubold, H J; Doi, T

    2012-01-01

    In 2010, the Human Space Technology Initiative (HSTI) was launched by the United Nations Office for Outer Space Affairs (UNOOSA) within the United Nations Programme on Space Applications. The Initiative aims at promoting international cooperation in human spaceflight and space exploration-related activities, creating awareness among countries on the benefits of utilizing human space technology and its applications, and building capacity in microgravity education and research. HSTI has conducted a series of outreach activities and expert meetings bringing together participants from around the world. HSTI will also be implementing science and educational activities in relevant areas to raise the capacities, particularly in developing countries, in pursuit of the development goals of the United Nations, thus contributing to promoting the peaceful uses of outer space.

  11. Girls with generalized joint hypermobility display changed muscle activity and postural sway during static balance tasks

    DEFF Research Database (Denmark)

    Juul-Kristensen, B; Johansen, Kl; Hendriksen, P;

    2016-01-01

    OBJECTIVES: To study knee muscle activity and static postural sway in girls with generalized joint hypermobility (GJH). METHOD: Sixteen girls with GJH and 11 girls with non-GJH (NGJH) aged 14 years, randomly recruited among schoolchildren, participated in this study. GJH inclusion criteria were: ......, compared with NGJH, static balance tasks with higher medial knee muscle activity relative to the lateral activity, and larger postural sway when vision was eliminated. The short- and long-term consequences should be studied further....

  12. The Relationship between Physical Activity and General Health among Menopausal Women in Ahvaz, Iran

    Science.gov (United States)

    Sharifi, Nasibeh; Jalili, Lida; Khazaeian, Somayeh; nia, Anvar-sadat Nayebi

    2017-01-01

    Introduction Most women experience significant changes in their general health status during menopause, which negatively affects their quality of life. Physical activity has also been shown to enhance quality of life. However, little is known about the effect of physical activity on women’s health during the menopausal transition. This study aimed to determine the relationship between physical activity and general health among menopausal women in Ahvaz, Iran. Methods This cross sectional study was carried out on 600 menopausal women using cluster random sampling during 2013–2014. Data collection tools were three questionnaires; women’s demographic characteristics, the Goldenberg’s questionnaire, and International physical activity questionnaire (IPAQ). Data were analyzed using descriptive and inferential statistics through SPSS version 19. The statistical tests were performed at the 95% confidence interval. Results There was a significant relationship between the total score of physical activity and physical health, social functioning, anxiety and depression (p0.05). Conclusion Physical activity is effective in improving general health in menopausal women. Proper training and effective interventions for regular physical activity can be important steps to promote the general health of menopausal women. PMID:28243418

  13. Ten years after the United Nations General Assembly Special Session (UNGASS): assessing drug problems, policies and reform proposals.

    Science.gov (United States)

    Reuter, Peter

    2009-04-01

    In 1998 the United Nations General Assembly Special Session resolved that governments would reduce drug production and consumption greatly within 10 years. With that period now elapsed, there is an interest in reviewing how successful this was and considering how drug policy could be improved. The demand for drugs in the world has stabilized mainly as a result of the interaction of epidemic forces, culture and economic development. Supply has become more concentrated and the menu of drugs has changed surprisingly slowly. Drug policy is shifting to a more explicitly tolerant configuration in Europe and a few other countries, but retains its ferocity in most of the world. The most prominent innovations under discussion have limited potential effects (heroin maintenance), have as yet been unproductive of policy interventions ('addiction is a brain disease') or have no political appeal (legalization). The option with the most scope is increased effort at diverting arrested drug users out of criminal justice systems. No prevention, treatment or enforcement strategies have demonstrated an ability to substantially affect the extent of drug use and addiction. The best that government interventions can do is to reduce the damaging consequences of drug use and drug control. More attention should be given to reductions in the intensity of drug enforcement, which has many unintended adverse consequences and yields few of the claimed gains.

  14. Physiotherapists' perceptions of and experiences with the discharge planning process in acute-care general internal medicine units in ontario.

    Science.gov (United States)

    Matmari, Lakshmi; Uyeno, Jennifer; Heck, Carol S

    2014-01-01

    To examine discharge planning of patients in general internal medicine units in Ontario acute-care hospitals from the perspective of physiotherapists. A cross-sectional study using an online questionnaire was sent to participants in November 2011. Respondents' demographic characteristics and ranking of factors were analyzed using descriptive statistics; t-tests were performed to determine between-group differences (based on demographic characteristics). Responses to open-ended questions were coded to identify themes. Mobility status was identified as the key factor in determining discharge readiness; other factors included the availability of social support and community resources. While inter-professional communication was identified as important, processes were often informal. Discharge policies, timely availability of other discharge options, and pressure for early discharge were identified as affecting discharge planning. Respondents also noted a lack of training in discharge planning; accounts of ethical dilemmas experienced by respondents supported these themes. Physiotherapists consider many factors beyond the patient's physical function during the discharge planning process. The improvement of team communication and resource allocation should be considered to deal with the realities of discharge planning.

  15. Economic Impacts of Potential Foot and Mouth Disease Agro-terrorism in the United States: A Computable General Equilibrium Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Oladosu, Gbadebo A [ORNL; Rose, Adam [University of Southern California, Los Angeles; Bumsoo, Lee [University of Illinois

    2013-01-01

    The foot and mouth disease (FMD) virus has high agro-terrorism potential because it is contagious, can be easily transmitted via inanimate objects and can be spread by wind. An outbreak of FMD in developed countries results in massive slaughtering of animals (for disease control) and disruptions in meat supply chains and trade, with potentially large economic losses. Although the United States has been FMD-free since 1929, the potential of FMD as a deliberate terrorist weapon calls for estimates of the physical and economic damage that could result from an outbreak. This paper estimates the economic impacts of three alternative scenarios of potential FMD attacks using a computable general equilibrium (CGE) model of the US economy. The three scenarios range from a small outbreak successfully contained within a state to a large multi-state attack resulting in slaughtering of 30 percent of the national livestock. Overall, the value of total output losses in our simulations range between $37 billion (0.15% of 2006 baseline economic output) and $228 billion (0.92%). Major impacts stem from the supply constraint on livestock due to massive animal slaughtering. As expected, the economic losses are heavily concentrated in agriculture and food manufacturing sectors, with losses ranging from $23 billion to $61 billion in the two industries.

  16. 40 CFR 63.7886 - What are the general standards I must meet for my affected remediation material management units?

    Science.gov (United States)

    2010-07-01

    ... meet for my affected remediation material management units? 63.7886 Section 63.7886 Protection of... meet for my affected remediation material management units? (a) For each remediation material... material management units exempted under paragraph (c) or (d) of this section. (b) For each affected...

  17. Practice patterns and outcomes of pediatric partial nephrectomy in the United States: Comparison between pediatric urology and general pediatric surgery.

    Science.gov (United States)

    Suson, Kristina D; Wolfe-Christensen, Cortney; Elder, Jack S; Lakshmanan, Yegappan

    2015-08-01

    In the United States, both pediatric urologists (PUROs) and general pediatric surgeons (GPSs) perform nephrectomies in children, with PUROs performing more nephrectomies overall, most commonly for benign causes. GPSs perform more nephrectomies for malignant causes. We questioned whether the same trends persisted for partial nephrectomy. We hypothesized that PUROs performed more partial nephrectomies for all causes, including malignancy. Our primary aim was to characterize the number of partial nephrectomies performed by PUROs and GPSs. We also compared short-term outcomes between subspecialties. We analyzed the Pediatric Health Information System (PHIS), a database encompassing data from 44 children's hospitals. Patients were ≤18 years old and had a partial nephrectomy (ICD-9 procedure code 554) carried out by PUROs or GPSs between 1 January, 2004 and June 30, 2013. Queried data points included surgeon subspecialty, age, gender, 3M™ All Patient Refined Diagnosis Related Groups (3M™ APR DRG) code, severity level, mortality risk, length of stay (LOS), and medical/surgical complication flags. Data points were compared in patients on whom PUROs and GPSs had operated. Statistical analysis included the Student t test, chi-square test, analysis of covariance, and logistic regression. Results are presented in the table. While PUROs performed the majority of partial nephrectomies, GPSs operated more commonly for malignancy. For surgeries performed for non-malignant indications, PURO patients had a shorter LOS and lower complication rate after controlling for statistically identified covariates. There was no difference in LOS or complication rate for patients with malignancy. A Pediatric Health Information System study of pediatric nephrectomy demonstrated PUROs performed more nephrectomies overall, but GPSs performed more surgeries for malignancy. The difference was less dramatic for partial nephrectomies (63% GPS, 37% PURO) than for radical nephrectomies (90% GPS, 10

  18. Nurse Activism in the newborn intensive care unit: actions in response to an ethical dilemma.

    Science.gov (United States)

    Settle, Peggy Doyle

    2014-03-01

    Nurses working in a newborn intensive care unit report that treatment decision disagreements for infants in their care may lead to ethical dilemmas involving all health-care providers. Applying Rest's Four-Component Model of Moral Action as the theoretical framework, this study examined the responses of 224 newborn intensive care unit nurses to the Nurses Ethical Involvement Survey. The three most frequent actions selected were as follows: talking with other nurses, talking with doctors, and requesting a team meeting. The multiple regression analysis indicates that newborn intensive care unit nurses with greater concern for the ethical aspects of clinical practice (p = .001) and an increased perception of their ability to influence ethical decision making (p = .018) were more likely to display Nurse Activism. Future research is necessary to identify other factors leading to and inhibiting Nurse Activism as these findings explained just 8.5% of the variance.

  19. Novel activity-dependent approaches to therapeutic hypnosis and psychotherapy: the general waking trance.

    Science.gov (United States)

    Rossi, Ernest; Erickson-Klein, Roxanna; Rossi, Kathryn

    2008-10-01

    This paper presents a highly edited version of a videotape made in 1980 by Marion Moore, M.D., showing Milton H. Erickson and Moore demonstrating novel, activity-dependent approaches to hand-levitation and therapeutic hypnosis on their subject, Ernest Rossi. Erickson's naturalistic and utilization approach is described in his very direct and surprising induction in a trance challenged patient. These novel, and surprising inductions are examples of how Erickson was prescient in developing activity-dependent approaches to therapeutic hypnosis and psychotherapy several generations before modern neuroscience documented the activity-dependent molecular-genomic mechanisms of memory, learning, and behavior change. Erickson describes a case where he utilized what he called, "The General Waking Trance" when he "dared" not use an obvious hypnotic induction. It is proposed that the states of intense mental absorption and response attentiveness that are facilitated by the general waking trance are functionally related to the three conditions neuroscientists have identified as novelty, enrichment, and exercise (both mental and physical), which can turn on activity-dependent gene expression and activity-dependent brain plasticity, that are the molecular-genomic and neural basis ofmemory, learning, consciousness, and behavior change. We recommend that the next step in investigating the efficacy of therapeutic hypnosis will be in partnering with neuroscientists to explore the possibilities and limitations of utilizing the activity-dependent approaches to hypnotic induction and the general waking trance in facilitating activity-dependent gene expression and brain plasticity.

  20. Functional Specificity of the Visual Word Form Area: General Activation for Words and Symbols but Specific Network Activation for Words

    Science.gov (United States)

    Reinke, Karen; Fernandes, Myra; Schwindt, Graeme; O'Craven, Kathleen; Grady, Cheryl L.

    2008-01-01

    The functional specificity of the brain region known as the Visual Word Form Area (VWFA) was examined using fMRI. We explored whether this area serves a general role in processing symbolic stimuli, rather than being selective for the processing of words. Brain activity was measured during a visual 1-back task to English words, meaningful symbols…

  1. Teen Sexual Activity, Pregnancy and Childbearing among Latinos in the United States. Fact Sheet.

    Science.gov (United States)

    National Campaign To Prevent Teen Pregnancy, Washington, DC.

    The Latino population is the fastest-growing major racial/ethnic group in the United States. By 2020, approximately 16 percent of the population will be Latino. This increase will be even more pronounced among teens. This fact sheet summarizes data from the National Vital Statistics Reports on reported sexual activity, pregnancy rates, and…

  2. What can Prudent Public Regulators Learn from the United Kingdom Government’s Nanotechnological Regulatory Activities?

    NARCIS (Netherlands)

    Dorbeck-Jung, Bärbel

    2007-01-01

    This contribution discusses the United Kingdom (UK) government’s regulatory activities related to nanotechnological development. The central question is what other prudent public regulation can learn from the UK government’s regulatory strategy, its regulatory attitude and its large variety of regul

  3. Activities of Partisan Units within Donetsk District (October, 1941 – July, 1942

    Directory of Open Access Journals (Sweden)

    Elena A. Shkribitko

    2012-11-01

    Full Text Available The article is concerned with the problem of partisan movement within Donetsk District in October, 1941 – July, 1942, describes combat activity of partisan units and warfare groups together with regular parts of the Red Army, focuses on partisans manpower and executive personnel training and arming, draws a conclusion, concerning high efficiency of partisan movement in Donbass.

  4. Motor unit activation order during electrically evoked contractions of paralyzed or partially paralyzed muscles

    NARCIS (Netherlands)

    Thomas, CK; Nelson, G; Than, L; Zijdewind, Inge

    The activation order of motor units during electrically evoked contractions of paralyzed or partially paralyzed thenar muscles was determined in seven subjects with chronic cervical spinal cord injury. The median nerve was stimulated percutaneously with pulses of graded intensity to produce

  5. Motor unit activation order during electrically evoked contractions of paralyzed or partially paralyzed muscles

    NARCIS (Netherlands)

    Thomas, CK; Nelson, G; Than, L; Zijdewind, Inge

    2002-01-01

    The activation order of motor units during electrically evoked contractions of paralyzed or partially paralyzed thenar muscles was determined in seven subjects with chronic cervical spinal cord injury. The median nerve was stimulated percutaneously with pulses of graded intensity to produce incremen

  6. Synchronization of lower limb motor unit activity during walking in human subjects

    DEFF Research Database (Denmark)

    Hansen, Naja L; Hansen, S; Christensen, L. O. D.

    2001-01-01

    Synchronization of motor unit activity was investigated during treadmill walking (speed: 3-4 km/h) in 25 healthy human subjects. Recordings were made by pairs of wire electrodes inserted into the tibialis anterior (TA) muscle and by pairs of surface electrodes placed over this muscle and a number...

  7. Rate of first recorded diagnosis of autism and other pervasive developmental disorders in United Kingdom general practice, 1988 to 2001

    Directory of Open Access Journals (Sweden)

    Smith Peter G

    2004-11-01

    Full Text Available Abstract Background There has been concern that the incidence of autism and other pervasive developmental disorders (PDDs is increasing. Previous studies have been smaller, restricted to autism (excluding other pervasive developmental disorders such as Asperger's syndrome, included boys only, or have not been based on a national sample. We investigated time trends in the rates of diagnosis of pervasive developmental disorders. Methods We analysed the rates of first diagnosis of pervasive developmental disorders among people registered with a practice contributing to the United Kingdom General Practice Research Database during the period 1988 to 2001. We included 1410 cases from over 14 million person-years of observation. The main outcome measures were rates of diagnosis of pervasive developmental disorders by year of diagnosis, year of birth, gender and geographical region. Results The rate increased progressively from 0.40/10,000 person-years (95% CI 0.30 to 0.54 in 1991 to 2.98/10,000 (95% CI 2.56 to 3.47 in 2001. A similar change occurred in the age standardised incidence ratios, from 35 (95% CI: 26–47 in 1991 to 365 (95% CI: 314–425 in 2001. The temporal increase was not limited to children born during specific years nor to children diagnosed in a specific time period. The rate of diagnosis of PDDs other than autism rose from zero for the period 1988–1992 to 1.06/10,000 person-years in 2001. The rate of diagnosis of autism also increased but to a lesser extent. There was marked geographical variation in rates, with standardised incidence ratios varying from 66 for Wales to 141 for the South East of England. Conclusions Better ascertainment of diagnosis is likely to have contributed to the observed temporal increase in rates of diagnosis of PDD, but we cannot exclude a real increase.

  8. The use of office-based sedation and general anesthesia by board certified pediatric dentists practicing in the United States.

    Science.gov (United States)

    Olabi, Nassim F; Jones, James E; Saxen, Mark A; Sanders, Brian J; Walker, Laquia A; Weddell, James A; Schrader, Stuart M; Tomlin, Angela M

    2012-01-01

    The purpose of this study is to explore the use of office-based sedation by board-certified pediatric dentists practicing in the United States. Pediatric dentists have traditionally relied upon self-administered sedation techniques to provide office-based sedation. The use of dentist anesthesiologists to provide office-based sedation is an emerging trend. This study examines and compares these two models of office-based sedations. A survey evaluating office-based sedation of diplomates of the American Board of Pediatric Dentistry (ABPD) based on gender, age, years in practice, practice types, regions, and years as a diplomate of the ABPD was completed by 494 active members. The results were summarized using frequencies and percentages. Relationships of dentist age, gender, and number of years in practice with the use of intravenous (IV) sedation was completed using two-way contingency tables and Mantel-Haenszel tests for ordered categorical data. Relationships of office-based sedation use and the type of one's practice were examined using Pearson chi-square tests. Of the 1917 surveys e-mailed, 494 completed the survey for a response rate of 26%. Over 70% of board-certified US pediatric dentists use some form of sedation in their offices. Less than 20% administer IV sedation, 20 to 40% use a dentist anesthesiologist, and 60 to 70% would use dentist anesthesiologists if one were available.

  9. The regulation of visitors conduction activity in the State System os Brazilian Conservation Units

    Directory of Open Access Journals (Sweden)

    Cristina Alves Nascimento

    2016-08-01

    Full Text Available Beyond to conserving biodiversity, conservation units must promote public use in contact with nature, assisting in increasing the economic resource of the area, approximating the society to nature and promoting their sustainable use. In Brazil, there are rules of the Ministry of Environment and Chico Mendes Institute for Biodiversity Conservation that regulate the conduction of visitors in federal conservation units. Remains to know how the activity is regulated in other spheres of the National Conservation Units System. Therefore, this article purpose to identify the legal basis for the conduction of visitors in the state conservation units and their adherence to guidelines of the Ministry of Environment. The methodology consisted in documentary research and data survey of the legal basis, done through visits to websites and sending e-mails to state management agencies. Adherence to the guidelines of the regulations was done through the evaluation to fulfillment or not from them. Legal basis were found in 18.5% of federal units of Brazil, being that only Espírito Santo and Rio de Janeiro meet almost all of the guideline. The conclusion was that there is a long way to go forward as the creation of rules and procedures that simultaneously encourage visitation accompanied to qualified conductors and biodiversity conservation. It is recommended greater efforts of state management agencies for the development of these legal basis, promoting improvements in desenvolviment of the activity and awareness of society.

  10. Communication and general concern criterion prior to activation of the rapid response team: a grounded theory.

    Science.gov (United States)

    Martland, Jarrad; Chamberlain, Diane; Hutton, Alison; Smigielski, Michael

    2015-11-30

    Objective Patients commonly show signs and symptoms of deterioration for hours or days before cardiorespiratory arrest. Rapid response teams (RRT) were created to improve recognition and response to patient deterioration in these situations. Activation criteria include vital signs or 'general concern' by a clinician or family member. The general concern criterion for RRT activation accounts for nearly one-third of all RRT activity, and although it is well established that communication deficits between staff can contribute to poorer outcomes for patients, there is little evidence pertaining to communication and its effects on the general concern RRT activation. Thus, the aim of the present study was to develop a substantive grounded theory related to the communication process between clinicians that preceded the activation of an RRT when general concern criterion was used.Methods Qualitative grounded theory involved collection of three types of data details namely personal notes from participants in focus groups with white board notes from discussions and audio recordings of the focus groups sessions. Focus groups were conducted with participants exploring issues associated with clinician communication and how it related to the activation of an RRT using the general concern criterion.Results The three main phases of coding (i.e. open, axial and selective coding) analysis identified 322 separate open codes. The strongest theme contributed to a theory of ineffective communication and decreased psychological safety, namely that 'In the absence of effective communication there is a subsequent increase in anxiety, fear or concern that can be directly attributed to the activation of an RRT using the 'general concern' criterion'. The RRT filled cultural and process deficiencies in the compliance with an escalation protocol. Issues such as 'not for resuscitation documentation' and 'inability to establish communication with and between medical or nursing personnel' rated

  11. Acid sphingomyelinase serum activity predicts mortality in intensive care unit patients after systemic inflammation: a prospective cohort study.

    Directory of Open Access Journals (Sweden)

    Matthias Kott

    Full Text Available INTRODUCTION: Acid sphingomyelinase is involved in lipid signalling pathways and regulation of apoptosis by the generation of ceramide and plays an important role during the host response to infectious stimuli. It thus has the potential to be used as a novel diagnostic marker in the management of critically ill patients. The objective of our study was to evaluate acid sphingomyelinase serum activity (ASM as a diagnostic and prognostic marker in a mixed intensive care unit population before, during, and after systemic inflammation. METHODS: 40 patients admitted to the intensive care unit at risk for developing systemic inflammation (defined as systemic inflammatory response syndrome plus a significant procalcitonin [PCT] increase were included. ASM was analysed on ICU admission, before (PCT before, during (PCT peak and after (PCT low onset of SIRS. Patients undergoing elective surgery served as control (N = 8. Receiver-operating characteristics curves were computed. RESULTS: ASM significantly increased after surgery in the eight control patients. Patients from the intensive care unit had significantly higher ASM on admission than control patients after surgery. 19 out of 40 patients admitted to the intensive care unit developed systemic inflammation and 21 did not, with no differences in ASM between these two groups on admission. In patients with SIRS and PCT peak, ASM between admission and PCT before was not different, but further increased at PCT peak in non-survivors and was significantly higher at PCT low compared to survivors. Survivors exhibited decreased ASM at PCT peak and PCT low. Receiver operating curve analysis on discrimination of ICU mortality showed an area under the curve of 0.79 for ASM at PCT low. CONCLUSIONS: In summary, ASM was generally higher in patients admitted to the intensive care unit compared to patients undergoing uncomplicated surgery. ASM did not indicate onset of systemic inflammation. In contrast to PCT however

  12. 77 FR 38397 - Agency Information Collection (Report of General Information) Activities Under OMB Review

    Science.gov (United States)

    2012-06-27

    ... AFFAIRS Agency Information Collection (Report of General Information) Activities Under OMB Review AGENCY... Veterans Benefits Administration, Department of Veterans Affairs, will submit the collection of information... describes the nature of the information collection and its expected cost and burden; it includes the...

  13. Using Computational Chemistry Activities to Promote Learning and Retention in a Secondary School General Chemistry Setting

    Science.gov (United States)

    Ochterski, Joseph W.

    2014-01-01

    This article describes the results of using state-of-the-art, research-quality software as a learning tool in a general chemistry secondary school classroom setting. I present three activities designed to introduce fundamental chemical concepts regarding molecular shape and atomic orbitals to students with little background in chemistry, such as…

  14. Effects of Active Learning on Enhancing Student Critical Thinking in an Undergraduate General Science Course

    Science.gov (United States)

    Kim, Kyoungna; Sharma, Priya; Land, Susan M.; Furlong, Kevin P.

    2013-01-01

    To enhance students' critical thinking in an undergraduate general science course, we designed and implemented active learning modules by incorporating group-based learning with authentic tasks, scaffolding, and individual reports. This study examined the levels of critical thinking students exhibited in individual reports and the students'…

  15. Using Computational Chemistry Activities to Promote Learning and Retention in a Secondary School General Chemistry Setting

    Science.gov (United States)

    Ochterski, Joseph W.

    2014-01-01

    This article describes the results of using state-of-the-art, research-quality software as a learning tool in a general chemistry secondary school classroom setting. I present three activities designed to introduce fundamental chemical concepts regarding molecular shape and atomic orbitals to students with little background in chemistry, such as…

  16. Generalization of the Activated Complex Theory of Reaction Rates. II. Classical Mechanical Treatment

    Science.gov (United States)

    Marcus, R. A.

    1964-01-01

    In its usual classical form activated complex theory assumes a particular expression for the kinetic energy of the reacting system -- one associated with a rectilinear motion along the reaction coordinate. The derivation of the rate expression given in the present paper is based on the general kinetic energy expression.

  17. Design and simulation of an activated sludge unit associated to a continuous reactor to remove heavy metals

    Energy Technology Data Exchange (ETDEWEB)

    D`Avila, J.S.; Nascimento, R.R. [Ambientec Consultoria Ltda., Aracaju, SE (Brazil)

    1993-12-31

    A software was developed to design and simulate an activated sludge unit associated to a new technology to remove heavy metals from wastewater. In this process, a continuous high efficiency biphasic reactor operates by using particles of activated peat in conjugation with the sludge unit. The results obtained may be useful to increase the efficiency or to reduce the design and operational costs involved in a activated sludge unit. (author). 5 refs., 2 tabs.

  18. Getting a Better Understanding of the Metric System--Implications if Adopted by the United States: Executive Summary. Report to the Congress of the United States by the Comptroller General.

    Science.gov (United States)

    Comptroller General of the U.S., Washington, DC.

    This General Accounting Office (GAO) document is a summary of a GAO report that discusses: (1) the implications if the United States converts to the metric system of weights and measures; and (2) the conversion experiences of other countries. Topics covered include national policy, impact on industry and the public, benefits, advantages,…

  19. In Vitro Activity of Delafloxacin against Contemporary Bacterial Pathogens from the United States and Europe, 2014

    Science.gov (United States)

    Pfaller, M. A.; Sader, H. S.; Rhomberg, P. R.

    2017-01-01

    ABSTRACT The in vitro activities of delafloxacin and comparator antimicrobial agents against 6,485 bacterial isolates collected from medical centers in Europe and the United States in 2014 were tested. Delafloxacin was the most potent agent tested against methicillin-susceptible Staphylococcus aureus (MSSA), methicillin-resistant S. aureus, Streptococcus pneumoniae, viridans group streptococci, and beta-hemolytic streptococci and had activity similar to that of ciprofloxacin and levofloxacin against certain members of the Enterobacteriaceae. Overall, the broadest coverage of the tested pathogens (Gram-positive cocci and Gram-negative bacilli) was observed with meropenem and tigecycline in both Europe and the United States. Delafloxacin was shown to be active against organisms that may be encountered in acute bacterial skin and skin structure infections, respiratory infections, and urinary tract infections. PMID:28167542

  20. A Progress Report on the Cooperative Development of a General Histology Program by Several Schools in Brazil and the United States.

    Science.gov (United States)

    Harris, Norman O.; And Others

    A programed course in general histology was completely developed by dental schools in the United States and Brazil. A group of international experts specified the course objectives, wrote and taped scripts for a series of 28 lectures of 50 minutes each, developed slides to accompany the lectures, prepared microphotographs and scripts to explain…

  1. Continuity of care : is the personal doctor still important? : A survey of general practitioners and family physicians in England and Wales, the United States, and The Netherlands

    NARCIS (Netherlands)

    Stokes, T.; Tarrant, C.; Mainous, A.G.; Schers, H.J.; Freeman, G.; Baker, R.

    2005-01-01

    PURPOSE: We determined the reported value general practitioners/family physicians in 3 different health care systems place on the various types of continuity of care. METHODS: We conducted a postal questionnaire survey in England and Wales, the United States, and The Netherlands. The participants we

  2. A general approach toward enhancement of pseudocapacitive performance of conducting polymers by redox-active electrolytes

    KAUST Repository

    Chen, Wei

    2014-12-01

    A general approach is demonstrated where the pseudocapacitive performance of different conducting polymers is enhanced in redox-active electrolytes. The concept is demonstrated using several electroactive conducting polymers, including polyaniline, polypyrrole, and poly(3,4-ethylenedioxythiophene). As compared to conventional electrolytes, the redox-active electrolytes, prepared by simply adding a redox mediator to the conventional electrolyte, can significantly improve the energy storage capacity of pseudocapacitors with different conducting polymers. The results show that the specific capacitance of conducting polymer based pseudocapacitors can be increased by a factor of two by utilization of the redox-active electrolytes. In fact, this approach gives some of the highest reported specific capacitance values for electroactive conducting polymers. Moreover, our findings present a general and effective approach for the enhancement of energy storage performance of pseudocapacitors using a variety of polymeric electrode materials. © 2014 Elsevier B.V. All rights reserved.

  3. 75 FR 47632 - New United Motor Manufacturing, Inc., Formerly a Joint Venture of General Motors Corporation and...

    Science.gov (United States)

    2010-08-06

    ... General Motors Corporation and Toyota Motor Corporation, Including On- Site Leased Workers From Corestaff, ABM Janitorial, Toyota Engineering and Manufacturing North America, NPA Coatings, Inc., and Premier... Motor Manufacturing, Inc., formerly a joint venture of General Motors Corporation and Toyota...

  4. 76 FR 10396 - New United Motor Manufacturing, Inc., Formerly a Joint Venture of General Motors Corporation and...

    Science.gov (United States)

    2011-02-24

    ... General Motors Corporation and Toyota Motor Corporation, Including On- Site Leased Workers From Corestaff, ABM Janitorial, Toyota Engineering and Manufacturing North America, NPA Coatings, Inc., Premier... of General Motors Corporation and Toyota Motor Corporation, including on-site leased workers...

  5. Calpain Activity Is Generally Elevated during Transformation but Has Oncogene-Specific Biological Functions

    Directory of Open Access Journals (Sweden)

    N.O. Carragher

    2004-01-01

    Full Text Available Several oncogene and tumor-suppressor gene products are known substrates for the calpain family of cysteine proteases, and calpain is required for transformation by v-src and tumor invasion. Thus, we have now addressed whether calpain is generally associated with transformation and how calpain contributes to oncogene function. Our results demonstrate that calpain activity is enhanced upon transformation induced by the v-Src, v-Jun, v-Myc, k-Ras, and v-Fos oncoproteins. Furthermore, elevated calpain activity commonly promotes focal adhesion remodelling, disruption of actin cytoskeleton, morphological transformation, and cell migration, although proteolysis of target substrates (such as focal adhesion kinase, talin, and spectrin is differently specified by individual oncoproteins. Interestingly, v-Fos differs from other common oncoproteins in not requiring calpain activity for actin/adhesion remodelling or migration of v-Fos transformed cells. However, anchorage-independent growth of all transformed cells is sensitive to calpain inhibition. In addition, elevated calpain activity contributes to oncogene-induced apoptosis associated with transformation by v-Myc. Taken together, these studies demonstrate that calpain activity is necessary for full cellular transformation induced by common oncoproteins, but has distinct roles in oncogenic events induced by individual transforming proteins. Thus, targeting calpain activity may represent a useful general strategy for interfering with activated protooncogenes in cancer cells.

  6. 10 CFR 50.13 - Attacks and destructive acts by enemies of the United States; and defense activities.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Attacks and destructive acts by enemies of the United... destructive acts by enemies of the United States; and defense activities. An applicant for a license to... an enemy of the United States, whether a foreign government or other person, or (b) use or...

  7. EFFECTS OF DYNAMIC AND STATIC STRETCHING WITHIN GENERAL AND ACTIVITY SPECIFIC WARM-UP PROTOCOLS

    Directory of Open Access Journals (Sweden)

    Michael Samson

    2012-06-01

    Full Text Available The purpose of the study was to determine the effects of static and dynamic stretching protocols within general and activity specific warm-ups. Nine male and ten female subjects were tested under four warm-up conditions including a 1 general aerobic warm-up with static stretching, 2 general aerobic warm-up with dynamic stretching, 3 general and specific warm-up with static stretching and 4 general and specific warm-up with dynamic stretching. Following all conditions, subjects were tested for movement time (kicking movement of leg over 0.5 m distance, countermovement jump height, sit and reach flexibility and 6 repetitions of 20 metre sprints. Results indicated that when a sport specific warm-up was included, there was an 0.94% improvement (p = 0.0013 in 20 meter sprint time with both the dynamic and static stretch groups. No such difference in sprint performance between dynamic and static stretch groups existed in the absence of the sport specific warm-up. The static stretch condition increased sit and reach range of motion (ROM by 2.8% more (p = 0.0083 than the dynamic condition. These results would support the use of static stretching within an activity specific warm-up to ensure maximal ROM along with an enhancement in sprint performance

  8. Predicting child physical activity and screen time: parental support for physical activity and general parenting styles.

    Science.gov (United States)

    Langer, Shelby L; Crain, A Lauren; Senso, Meghan M; Levy, Rona L; Sherwood, Nancy E

    2014-07-01

    To examine relationships between parenting styles and practices and child moderate-to-vigorous physical activity (MVPA) and screen time. Participants were children (6.9 ± 1.8 years) with a body mass index in the 70-95th percentile and their parents (421 dyads). Parent-completed questionnaires assessed parental support for child physical activity (PA), parenting styles and child screen time. Children wore accelerometers to assess MVPA. Parenting style did not predict MVPA, but support for PA did (positive association). The association between support and MVPA, moreover, varied as a function of permissive parenting. For parents high in permissiveness, the association was positive (greater support was related to greater MVPA and therefore protective). For parents low in permissiveness, the association was neutral; support did not matter. Authoritarian and permissive parenting styles were both associated with greater screen time. Parenting practices and styles should be considered jointly, offering implications for tailored interventions. © The Author 2014. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  9. Predicting Child Physical Activity and Screen Time: Parental Support for Physical Activity and General Parenting Styles

    Science.gov (United States)

    Crain, A. Lauren; Senso, Meghan M.; Levy, Rona L.; Sherwood, Nancy E.

    2014-01-01

    Objective: To examine relationships between parenting styles and practices and child moderate-to-vigorous physical activity (MVPA) and screen time. Methods: Participants were children (6.9 ± 1.8 years) with a body mass index in the 70–95th percentile and their parents (421 dyads). Parent-completed questionnaires assessed parental support for child physical activity (PA), parenting styles and child screen time. Children wore accelerometers to assess MVPA. Results: Parenting style did not predict MVPA, but support for PA did (positive association). The association between support and MVPA, moreover, varied as a function of permissive parenting. For parents high in permissiveness, the association was positive (greater support was related to greater MVPA and therefore protective). For parents low in permissiveness, the association was neutral; support did not matter. Authoritarian and permissive parenting styles were both associated with greater screen time. Conclusions: Parenting practices and styles should be considered jointly, offering implications for tailored interventions. PMID:24812256

  10. Proposal for loadable and erasable optical memory unit based on dual active microring optical integrators

    Science.gov (United States)

    Ding, Yunhong; Zhang, Xiaobei; Zhang, Xinliang; Huang, Dexiu

    2008-11-01

    A novel approach for loadable and erasable optical memory unit based on dual microring optical integrators is proposed and studied. The optical integrator, which can generate an optical step function for data storing, is synthesized using active media for loss compensation and a tunable phase shifter for data reading at any time. The input data into the memory is return-to-zero (RZ) signal, and the output data read from the memory is also RZ format with a narrower pulse width. An optical digital register based on the proposed optical memory unit is also investigated and simulated, which shows the potential for large scale data storage and serial-to-parallel data conversion. A great number of such memory units can be densely integrated on a photonic circuit for future large scale data storage and buffer.

  11. OPTIMIZATION OF ACTIVITIES FOR CONTROLLING ADMINISTRATIVE AND ECONOMIC LIFE OF ARMY UNITS

    Directory of Open Access Journals (Sweden)

    Khlebnikov V. Y.

    2015-03-01

    Full Text Available In the article we consider main objectives of system approach, as a research method of difficult objects, administrative activity supervision and analyses, components of which are processes of check and comparison of the actual results to the set parameters. The theory of decision-making focused on development and search of optimum results on various problems with a significant amount of communications and dependences, restrictions and versions of decisions has been developed. Optimization of economic activity supervision in a military unit and, in particular, competence of officials is considered. The use of assessment results of the subordinated divisions (services administrative activity on the basis of experts' opinion at adoption of administrative decisions. Introduction of mathematical methods in the monitoring procedure of administrative activity is analyzed. Ways to improve the organization of administrative activity supervision by means of expert assessment method on the basis of introduction of the settlement network Expert program are offered. This software product provides fast data input and an efficiency assessment of administrative activity in a division (service of a military unit. To judge the quantitative characteristics of administrative activity and evident representation of a change tendency of the observed values on the monitor screen of the automated workplace of the official, the information in the form of a tabular and graphic representation (charts is displayed

  12. PRE-AND POST-ACTIVITY STRETCHING PRACTICES OF COLLEGIATE ATHLETIC TRAINERS IN THE UNITED STATES.

    Science.gov (United States)

    Popp, Jennifer K; Bellar, David; Hoover, Donald L; Craig, Bruce W; Leitzelar, Brianna N; Wanless, Elizabeth A; Judge, Lawrence W

    2015-02-14

    The aim of the study was to investigate the knowledge and practices of collegiate-certified athletic trainers (ATs) in the United States. Participants (n= 521) were provided an overview of the study, as well as a hyperlink to a web-based survey. The "Pre- and Post-Activity Practices in Athletic Training Questionnaire" consisted of demographic items and elements to measure knowledge and practices related to pre- and post-activity stretching routines. In previous studies, the survey demonstrated construct validity, α = .722. Pearson chi-square test was used to evaluate goodness of fit, and kappa was calculated to measure agreement between items. Only 32.2% of ATs recommended dynamic stretching (DS) to be performed pre-activity, whereas a larger percentage (42.2%) recommended a combination of static stretching (SS) and DS. ATs reported that only 28.0% of athletes are performing DS prior to activity. Conversely, 60.6% of collegiate ATs recommended SS post-exercise, and 61.0% of athletes agree and perform post-workout static stretching (κ=0.761, P<0.001). Collegiate ATs appear to under-utilize the current research evidence, which indicates that DS is more beneficial than SS when used pre-activity, and ATs continue to regularly incorporate SS in their pre-activity routines. However, there is evidence that collegiate ATs in the United States emphasize SS post-activity in a manner consistent with current research.

  13. Changes in health risks among the participants in the United Auto Workers--General Motors LifeSteps Health Promotion Program.

    Science.gov (United States)

    Yen, L; Edington, M P; McDonald, T; Hirschland, D; Edington, D W

    2001-01-01

    To examine health risk changes among participants of a multicomponent worksite health promotion program. A study using health risk changes among health risk appraisal (HRA) participants linked to program participation records. Baseline risk and participation in multiple programs were examined in relation to risk change in multivariate models. Worksite health promotion programming sponsored by the United Auto Workers (UAW) and General Motors (GM). Active employees (12,984) who voluntarily participated in an HRA in each of two program years. The nationwide program was a mailed HRA and a 1-800 nurse line. A pilot program (implemented in two cities) added screening, wellness programs, a materials resource, and, for high risk participants, health coaching and vouchers for medical office visits. Using 13 selected health risk factors from the HRA, changes in overall health risks were measured as program outcomes in three ways: one-directional, net, and risk status change. A greater decrease in the number of health risks was observed with increased program participation. The decrease was significantly related to the number of baseline risk factors and eligibility for high risk programs. Associated with program participation, the number of people at low risk status increased from 70.1% to 71.3% at year 2 among nationwide participants and from 52.4% to 58.9% among pilot participants. Participation was associated with a significant impact on health risk. Baseline risk of participants and eligibility for high risk programs were necessary factors to control when measuring program effects on health risk changes.

  14. LA ADQUISICIÓN DE LA PERICIA EN JUDO: ACTIVIDADES GENERALES Y COTIDIANAS [The acquisition of expertise in Judo: general and daily activities] The acquisition of expertise in Judo: general and daily activities

    Directory of Open Access Journals (Sweden)

    Damián Iglesias Gallego

    2012-06-01

    Full Text Available Normal 0 21 false false false ES X-NONE X-NONE MicrosoftInternetExplorer4 El objetivo de esta investigación es analizar la precepción que tienen los judocas de diferente nivel de pericia respecto a las actividades generales y cotidianas. La muestra de estudio estuvo compuesta por judocas de nivel regional (n = 9, nacional (n = 27 e internacional (n = 40. Para la recogida de datos se utilizó el cuestionario como instrumento de medida, a través del cual los sujetos valoraron cada actividad desde cuatro dimensiones: concentración, esfuerzo físico, diversión y rendimiento. Los judocas de nivel internacional destacaron la dieta como la actividad más importante para mejorar el rendimiento dentro de las actividades generales. En cuanto a las actividades cotidianas todos los judocas destacaron dormir como la actividad más importante para mejorar el rendimiento. Palabras clave: Práctica deliberada, rendimiento, pericia, judo.The objective of this research is to analyze the preception that have the judokas of different levels of expertise regarding the general and daily activities. The study sample consisted of regional level judo (n = 9, national (n = 27 and international (n = 40. For data collection questionnaire was used as a measuring instrument, through which the subjects rated each activity from four dimensions: concentration, physical exertion, fun and performance. The international judokas stressed the diet as the most important activity to improve performance within the overall activities. With regard to daily activities sleep all judokas highlighted as the most important activity to improve performance.   Key words: Deliberate practice, performance, expertise, judo.

  15. Reduced order generalized integrators with phase compensation for three-phase active power filter

    DEFF Research Database (Denmark)

    Xie, Chuan; Li, Kai; Zhao, Xin

    2017-01-01

    Current regulation is a critical issue for the stable operation of three-phase active power filters (APF). The challenge of the current controller lies in how to track the high slew rate reference with zero steady-state error in a fast and accurate way. Conventionally, multiple paralleled second-order...... generalized integrators (SOGIs) are utilized to achieve those objectives. However, it will increase the computational burden due to calculation of the multiple paralleled SOGIs. To overcome this issue, phase compensated reduced order generalized integrator (ROGI) is proposed in this paper. Compared...

  16. Age independent and position-dependent alterations in motor unit activity of the biceps brachii.

    Science.gov (United States)

    Harwood, B; Edwards, D L; Jakobi, J M

    2010-09-01

    In the biceps brachii, age-related differences in synaptic excitability and muscle architecture may affect motor unit (MU) activity differently depending on the position of the forearm. It was hypothesised that as a result of these age-related differences, greater changes in MU activity would accompany a change in forearm position in old when compared with young men. Six young (22 +/- 3 years) and six old (84 +/- 3 years) men maintained isometric elbow flexion at 10% of maximal voluntary contraction (MVC) during changes in forearm position. Forty-nine MUs in the short (SBB) and long (LBB) heads of the biceps brachii were followed. Motor unit recruitment and de-recruitment thresholds, motor unit discharge rates (MUDRs), and MU discharge variability were measured. Although an age-related decrease in MU recruitment thresholds, and increase in MU discharge variability was evident, changes in forearm position influenced MUDRs similarly in young and old men (P = 0.27). Motor unit recruitment thresholds of the SBB were highest in the pronated position (8.2 +/- 2.9 %MVC), whereas in the LBB they were highest in the supinated position (8.6 +/- 2.0 %MVC). Motor unit discharge rates of the LBB did not change with forearm position. In the SBB, MUDRs were highest when the forearm was supinated, and also greater when compared with the LBB in this position. No position-dependent changes were observed for MU discharge variability in the LBB, but the SBB exhibited greatest MU discharge variability in the pronated position. The results suggest that MU activity is modulated following a change in forearm position, but the response is similar in young and old adults.

  17. Coherence of EMG activity and single motor unit discharge patterns in human rhythmical force production.

    Science.gov (United States)

    Sosnoff, Jacob J; Vaillancourt, David E; Larsson, Lars; Newell, Karl M

    2005-03-30

    The purpose of this study was to examine the modulation of the motor neuronal pool as a function of task dynamics. Specifically, we investigated the effects of task frequency on the single motor unit discharge pattern, electromyogram (EMG) activity and effector force output. Myoelectric activity and effector force were recorded while young adults isometrically abducted their first dorsal interosseus at five sinusoidal targets (0.5 Hz, 1 Hz, 2 Hz, 3 Hz and 4 Hz) and at two force levels (5% and 25% maximum voluntary contraction (MVC)). Individual motor unit spike trains were isolated from the EMG. Auto-spectral and coherence analyses were performed on the force output, EMG and motor unit spike trains. The frequency of maximal coherence between the EMG and force output closely corresponded to the target frequency in all conditions. There was a broadband distribution of power with multiple peaks in the EMG and motor unit spectrums in the 0.5 Hz and 1 Hz targets. However, the EMG and motor unit spectrums in the 2 Hz, 3 Hz and 4 Hz targets were characterized by an increasingly narrower band of activity with one dominant peak that closely corresponded to the target. There is high coherence between EMG output and target force frequency, but the relative contribution of the fast and slow neuromuscular bands are differentially influenced by the task frequency. The rhythmical organization of neuromuscular output in the 0.5 Hz task is relatively broadband and similar to that shown previously for constant level force output. The frequency structure of neuromuscular organization becomes increasingly more narrowband as the frequency of the target increases (2-4 Hz). The modulation of the motor neuronal pool is adaptive and depends on the relative contribution of feedback and feedforward control processes, which are driven by the task demands.

  18. The compatibility of general managers' activities and intentions in managing change in the NHS.

    Science.gov (United States)

    Spurgeon, P; Barwell, F

    1990-03-01

    As Hales (1986) has observed, the problem of much of the managerial research to date has been the reluctance to ask why managers behave in the way they do. The behaviour of general managers in tackling organisational change in the NHS needs to be viewed not only with respect to what is done but also with respect to how personal and organisational objectives are construed. In other words, the implementation of organisational change ultimately rests on how general managers perceive the nature of this change and their role in structuring their own personal and organisational objectives into appropriate activities. Examining the compatibility of managerial activities and the underlying values and intentions which support them is of critical importance in any cognitively-based approach. These intentions provide an important link between perceptions (i.e. how the organisation is construed) and behaviour (i.e. what activities managers choose to perform). Understanding the conceptual frameworks which underpin managerial activities could have profound implications for assessing the performance of general managers.

  19. Moving the Barricades to Physical Activity: A Qualitative Analysis of Open Streets Initiatives Across the United States.

    Science.gov (United States)

    Eyler, Amy A; Hipp, J Aaron; Lokuta, Julie

    2015-01-01

    Ciclovía, or Open Streets initiatives, are events where streets are opened for physical activity and closed to motorized traffic. Although the initiatives are gaining popularity in the United States, little is known about planning and implementing them. The goals of this paper are to explore the development and implementation of Open Streets initiatives and make recommendations for increasing the capacity of organizers to enhance initiative success. Phenomenology with qualitative analysis of structured interviews was used. Study setting was urban and suburban communities in the United States. Study participants were organizers of Open Streets initiatives in U.S. cities. Using a list of 47 events held in 2011, 27 lead organizers were interviewed by telephone about planning, implementation, and lessons learned. The interviews were digitally recorded and transcribed. A phenomenologic approach was used, an initial coding tool was developed after reviewing a sample of transcripts, and constant comparative coding methodology was applied. Themes and subthemes were generated from codes. The most common reasons for initiation were to highlight or improve health and transportation. Most initiatives aimed to reach the general population, but some targeted families, children, or specific neighborhoods. Getting people to understand the concept of Open Streets was an important challenge. Other challenges included lack of funding and personnel, and complex logistics. These initiatives democratize public space for citizens while promoting physical activity, social connectedness, and other broad agendas. There are opportunities for the research community to contribute to the expanse and sustainability of Open Streets, particularly in evaluation and dissemination.

  20. The generalized Hill model: A kinematic approach towards active muscle contraction

    Science.gov (United States)

    Göktepe, Serdar; Menzel, Andreas; Kuhl, Ellen

    2014-12-01

    Excitation-contraction coupling is the physiological process of converting an electrical stimulus into a mechanical response. In muscle, the electrical stimulus is an action potential and the mechanical response is active contraction. The classical Hill model characterizes muscle contraction though one contractile element, activated by electrical excitation, and two non-linear springs, one in series and one in parallel. This rheology translates into an additive decomposition of the total stress into a passive and an active part. Here we supplement this additive decomposition of the stress by a multiplicative decomposition of the deformation gradient into a passive and an active part. We generalize the one-dimensional Hill model to the three-dimensional setting and constitutively define the passive stress as a function of the total deformation gradient and the active stress as a function of both the total deformation gradient and its active part. We show that this novel approach combines the features of both the classical stress-based Hill model and the recent active-strain models. While the notion of active stress is rather phenomenological in nature, active strain is micro-structurally motivated, physically measurable, and straightforward to calibrate. We demonstrate that our model is capable of simulating excitation-contraction coupling in cardiac muscle with its characteristic features of wall thickening, apical lift, and ventricular torsion.

  1. Activities Contributing to Total Energy Expenditure in the United States: Results from the NHAPS Study

    Directory of Open Access Journals (Sweden)

    Block Gladys

    2004-02-01

    Full Text Available Abstract Background Physical activity is increasingly recognized as an important factor influencing health and disease status. Total energy expenditure, both low-intensity and high-intensity, contributes to maintenance of healthy body weight. This paper presents the results of a quantitative approach to determining the activities that contribute to total energy expenditure in the United States. Methods Data from the National Human Activity Pattern Survey (NHAPS were used. In 1992–1994 the NHAPS sampled 4,185 females and 3,330 males, aged 18 years and over, weighted to be representative of the 48 contiguous United States. A detailed report of each activity performed in the previous 24 hours was obtained. A score was created for each activity, by multiplying duration and intensity for each individual and summing across individuals. This score was then used to rank each activity according to its contribution to total population energy expenditure, for the total sample and separately for each gender, race, age, region, and season. Results This analysis reveals our society to be primarily sedentary; leisure time physical activity contributed only approximately 5% of the population's total energy expenditure. Not counting sleeping, the largest contributor to energy expenditure was "Driving a car", followed by "Office work" and "Watching TV". Household activities accounted for 20.1% and 33.3% of energy expenditure for males and females respectively. Conclusion The information presented in this paper may be useful in identifying common activities that could be appropriate targets for behavioral interventions to increase physical activity.

  2. Exercise and limitations in physical activity levels among new dialysis patients in the United States: an epidemiologic study.

    LENUS (Irish Health Repository)

    Stack, Austin G

    2008-12-01

    Epidemiologic studies of physical activity among patients with end-stage renal disease (ESRD) are lacking. The aim of this study was to describe the patterns of physical activity among new dialysis patients in the United States.

  3. Antimicrobial Suspectibility of Bacterial Isolated from Burn Unit in Dr. Hasan Sadikin General Hospital Bandung, Indonesia from June to September 2013

    Directory of Open Access Journals (Sweden)

    Yodya Evila

    2015-09-01

    Full Text Available Background: Development of infection in burned patients is a crucial matter because it may increase morbidity and mortality. Factors contributing to high risk for infections are disrupted skin barrier, dysfunction of the immune system and prolonged hospitalization. Crowded hospital condition and transfer of patients from one unit to another can affect development of infection caused by environmental factors. The aim of the study was to identify the antimicrobial suspectibility of bacterial isolated from Burn Unit in Dr. Hasan Sadikin General Hospital, Bandung. Methods: A descriptive study was carried out in Burn Unit Dr. Hasan Sadikin General Hospital Bandung, Indonesia, from June to September 2013. A total of 30 environment samples were collected and cultured to identify the bacterias. Futhermore, the colonies found, underwent antimicrobial susceptibility test. Results: Most common bacteria found from the environmental samples in Burn Unit was Staphylococcus saprophyticus (24%. Other bacterias found were Klebsiella pneumonia (17%, Acinetobacter baumanii (15%, Staphylococcus epidermidis (12%, Bacillus sp.(12%, Pseudomonas sp.(7%, Staphylococcus aureus (5%, Enterobacter aerogenes (5% and Serratia sp. (2%. Some bacteria still had good sensitivity to antibiotics while the Enterobacteriaceae were almost completely resistant to antimicrobial used in the study. Conclusions: The most common bacteria found from the environment samples in Burn Unit is Staphylococcuss aprophyticus. Additionally, Klebsiella pneumoniae as one of the Enterobacteriaceae groups, appears as an emerging hospital associated infection pathogen with their resistant to many antimicrobials.

  4. Application of the Activity-Based Costing Method for Unit-Cost Calculation in a Hospital.

    Science.gov (United States)

    Javid, Mahdi; Hadian, Mohammad; Ghaderi, Hossein; Ghaffari, Shahram; Salehi, Masoud

    2015-05-17

    Choosing an appropriate accounting system for hospital has always been a challenge for hospital managers. Traditional cost system (TCS) causes cost distortions in hospital. Activity-based costing (ABC) method is a new and more effective cost system. This study aimed to compare ABC with TCS method in calculating the unit cost of medical services and to assess its applicability in Kashani Hospital, Shahrekord City, Iran.‎ This cross-sectional study was performed on accounting data of Kashani Hospital in 2013. Data on accounting reports of 2012 and other relevant sources at the end of 2012 were included. To apply ABC method, the hospital was divided into several cost centers and five cost categories were defined: wage, equipment, space, material, and overhead costs. Then activity centers were defined. ABC method was performed into two phases. First, the total costs of cost centers were assigned to activities by using related cost factors. Then the costs of activities were divided to cost objects by using cost drivers. After determining the cost of objects, the cost price of medical services was calculated and compared with those obtained from TCS.‎ The Kashani Hospital had 81 physicians, 306 nurses, and 328 beds with the mean occupancy rate of 67.4% during 2012. Unit cost of medical services, cost price of occupancy bed per day, and cost per outpatient service were calculated. The total unit costs by ABC and TCS were respectively 187.95 and 137.70 USD, showing 50.34 USD more unit cost by ABC method. ABC method represented more accurate information on the major cost components. By utilizing ABC, hospital managers have a valuable accounting system that provides a true insight into the organizational costs of their department.

  5. The Removal of Composite Reactive Dye from Dyeing Unit Effluent Using Sewage Sludge Derived Activated Carbon

    OpenAIRE

    REDDY, Sajjala SREEDHAR

    2006-01-01

    Activated carbon was prepared from dried municipal sewage sludge and batch mode adsorption experiments were conducted to study its potential to remove composite reactive dye from dyeing unit effluent. Adsorption parameters for the Langmuir and Freundlich isotherms were determined and the effects of effluent pH, adsorbent dosage, contact time and initial dye concentration were studied. The toxicity characteristic leaching protocol (TCLP) was used to assess the acceptability of sewage ...

  6. Activity-based costing in radiology. Application in a pediatric radiological unit.

    Science.gov (United States)

    Laurila, J; Suramo, I; Brommels, M; Tolppanen, E M; Koivukangas, P; Lanning, P; Standertskjöld-Nordenstam, G

    2000-03-01

    To get an informative and detailed picture of the resource utilization in a radiology department in order to support its pricing and management. A system based mainly on the theoretical foundations of activity-based costing (ABC) was designed, tested and compared with conventional costing. The study was performed at the Pediatric Unit of the Department of Radiology, Oulu University Hospital. The material consisted of all the 7,452 radiological procedures done in the unit during the first half of 1994, when both methods of costing where in use. Detailed cost data were obtained from the hospital financial and personnel systems and then related to activity data captured in the radiology information system. The allocation of overhead costs was greatly reduced by the introduction of ABC compared to conventional costing. The overhead cost as a percentage of total costs dropped to one-fourth of total costs, from 57% to 16%. The change of unit costs of radiological procedures varied from -42% to +82%. Costing is much more detailed and precise, and the percentage of unspecified allocated overhead costs diminishes drastically when ABC is used. The new information enhances effective departmental management, as the whole process of radiological procedures is identifiable by single activities, amenable to corrective actions and process improvement.

  7. Motivation towards extracurricular activities and motivation at school: A test of the generalization effect hypothesis.

    Science.gov (United States)

    Denault, Anne-Sophie; Guay, Frédéric

    2017-01-01

    Participation in extracurricular activities is a promising avenue for enhancing students' school motivation. Using self-determination theory (Deci & Ryan, 2000), the goal of this study was to test a serial multiple mediator model. In this model, students' perceptions of autonomy support from their extracurricular activity leader predicted their activity-based intrinsic and identified regulations. In turn, these regulations predicted their school-based intrinsic and identified regulations during the same school year. Finally, these regulations predicted their school-based intrinsic and identified regulations one year later. A total of 276 youths (54% girls) from disadvantaged neighborhoods were surveyed over two waves of data collection. The proposed mediation model was supported for both types of regulation. These results highlight the generalization effects of motivation from the extracurricular activity context to the school context. Copyright © 2016 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  8. Second-Order Perturbation Theory for Generalized Active Space Self-Consistent-Field Wave Functions.

    Science.gov (United States)

    Ma, Dongxia; Li Manni, Giovanni; Olsen, Jeppe; Gagliardi, Laura

    2016-07-12

    A multireference second-order perturbation theory approach based on the generalized active space self-consistent-field (GASSCF) wave function is presented. Compared with the complete active space (CAS) and restricted active space (RAS) wave functions, GAS wave functions are more flexible and can employ larger active spaces and/or different truncations of the configuration interaction expansion. With GASSCF, one can explore chemical systems that are not affordable with either CASSCF or RASSCF. Perturbation theory to second order on top of GAS wave functions (GASPT2) has been implemented to recover the remaining electron correlation. The method has been benchmarked by computing the chromium dimer ground-state potential energy curve. These calculations show that GASPT2 gives results similar to CASPT2 even with a configuration interaction expansion much smaller than the corresponding CAS expansion.

  9. Protection motivation theory and physical activity in the general population: a systematic literature review.

    Science.gov (United States)

    Bui, Linh; Mullan, Barbara; McCaffery, Kirsten

    2013-01-01

    An appropriate theoretical framework may be useful for guiding the development of physical activity interventions. This review investigates the effectiveness of the protection motivation theory (PMT), a model based on the cognitive mediation processes of behavioral change, in the prediction and promotion of physical activity participation. A literature search was conducted using the databases MEDLINE, PsycINFO, PubMed, and Web of Science, and a manual search was conducted on relevant reference lists. Studies were included if they tested or applied the PMT, measured physical activity, and sampled from healthy populations. A total of 20 studies were reviewed, grouped into four design categories: prediction, stage discrimination, experimental manipulation, and intervention. The results indicated that the PMT's coping appraisal construct of self-efficacy generally appears to be the most effective in predicting and promoting physical activity participation. In conclusion, the PMT shows some promise, however, there are still substantial gaps in the evidence.

  10. Recreational activities performed with neoplasia carrier Inpatients in a general hospital

    Directory of Open Access Journals (Sweden)

    Caroline de Castro Moura

    2012-09-01

    Full Text Available This study aims at apprehending the contribution of recreational activities in the treatment of hospitalized cancer patients and identifying the most stimulating resources for them. This is a qualitative research of phenomenological nature, it was approved by the Ethics in Research Committee, Protocol 139/2010. It was conducted with patients with cancer in a general hospital, located in Alfenas, in March and April, 2011.The research began from these guiding questions: What are your thoughts on the recreational team work and the activities they do? What do you suggest for this group to be developed? It was perceived that ludic activities help patients to face the disease, that they eased the interaction between the recreational group and the multiprofessional team, besides providing a happy and welcoming environment. The most well accepted activities were music and games the clowns provided. We suggest implementing the humanization by using ludic resources.

  11. General method for the preparation of active esters by palladium-catalyzed alkoxycarbonylation of aryl bromides.

    Science.gov (United States)

    de Almeida, Angelina M; Andersen, Thomas L; Lindhardt, Anders T; de Almeida, Mauro V; Skrydstrup, Troels

    2015-02-06

    A useful method was developed for the synthesis of active esters by palladium-catalyzed alkoxycarbonylation of (hetero)aromatic bromides. The protocol was general for a range of oxygen nucleophiles including N-hydroxysuccinimide (NHS), pentafluorophenol (PFP), hexafluoroisopropyl alcohol (HFP), 4-nitrophenol, and N-hydroxyphthalimide. A high functional group tolerance was displayed, and several active esters were prepared with good to excellent isolated yields. The protocol was extended to access an important synthetic precursor to the HIV-protease inhibitor, saquinavir, by formation of an NHS ester followed by acyl substitution.

  12. Promoting Active Learning in Calculus and General Physics through Interactive and Media-Enhanced Lectures

    Directory of Open Access Journals (Sweden)

    Guoqing Tang

    2004-02-01

    Full Text Available In this paper we present an approach of incorporating interactive and media-enhanced lectures to promote active learning in Calculus and General Physics courses. The pedagogical practice of using interactive techniques in lectures to require "heads-on" and "hands-on" learning, and involve students more as active participants than passive receivers is a part of academic curricular reform efforts undertaken currently by the mathematics, physics and chemistry departments at North Carolina A&T State University under the NSF funded project "Talent-21: Gateway for Advancing Science and Mathematics Talents."

  13. Promoting Active Learning in Calculus and General Physics through Interactive and Media-Enhanced Lectures

    Directory of Open Access Journals (Sweden)

    Guoqing Tang

    2004-02-01

    Full Text Available In this paper we present an approach of incorporating interactive and media-enhanced lectures to promote active learning in Calculus and General Physics courses. The pedagogical practice of using interactive techniques in lectures to require "heads-on" and "hands-on" learning, and involve students more as active participants than passive receivers is a part of academic curricular reform efforts undertaken currently by the mathematics, physics and chemistry departments at North Carolina A&T State University under the NSF funded project "Talent-21: Gateway for Advancing Science and Mathematics Talents."

  14. Activation of Dopamine Neurons is Critical for Aversive Conditioning and Prevention of Generalized Anxiety

    OpenAIRE

    2011-01-01

    Generalized anxiety is thought to result, in part, from impairments in contingency awareness during conditioning to cues that predict aversive or fearful outcomes. Dopamine neurons of the ventral midbrain exhibit heterogeneous responses to aversive stimuli that are thought to provide a critical modulatory signal to facilitate orienting to environmental changes and assignment of motivational value to unexpected events. Here, we describe a mouse model in which activation of dopamine neurons in ...

  15. Generalization of an Active Electronic Notebook for Teaching Multiple Programming Languages

    OpenAIRE

    Torabzadeh-Tari, Mohsen; Fritzson, Peter; Pop, Adrian; Sjölund, Martin

    2010-01-01

    In this paper we present a generalization of the active electronic notebook, OMNotebook, for handling multiple programming languages for educational purposes. OMNotebook can be an alternative or complementary tool to the traditional teaching method with lecturing and reading textbooks. Experience shows that using such an electronic book will lead to more engagement from the students. OMNotebook can contain technical computations and text, as well as graphics. Hence it is a suitable tool for t...

  16. A statistical assessment of tropical cyclone activity in atmospheric general circulation models

    OpenAIRE

    Suzana J. Camargo; Barnston, Anthony G; Zebiak, Stephen E.

    2005-01-01

    The properties of tropical cyclones in three low-resolution atmospheric general circulation models (AGCMs) in seven ocean basins are discussed. The models are forced by prescribed, observed sea surface temperatures over a period of 40 yr, and their simulations of tropical cyclone activity are compared with observations. The model cyclone characteristics considered include genesis position, number of cyclones per year, seasonality, accumulated cyclone energy, track locations, and number of sto...

  17. Recreational activities performed with neoplasia carrier Inpatients in a general hospital

    OpenAIRE

    2012-01-01

    This study aims at apprehending the contribution of recreational activities in the treatment of hospitalized cancer patients and identifying the most stimulating resources for them. This is a qualitative research of phenomenological nature, it was approved by the Ethics in Research Committee, Protocol 139/2010. It was conducted with patients with cancer in a general hospital, located in Alfenas, in March and April, 2011.The research began from these guiding questions: What are your thoughts o...

  18. United States Pharmacopeia activities in the area of vaccines, virology and immunology.

    Science.gov (United States)

    Morris, Tina S

    2005-03-18

    The United States Pharmacopeia (USP) develops public standards for medical products that are enforceable by FDA. USP general information chapters have been providing industrial and academic researchers alike with crucial guidance especially in areas where there is absence of regulatory guidance. In an effort to meet the challenge of rapid advances in vaccine research and manufacturing, the Council of Experts Committee for Vaccines, Virology, and Immunology of the US Pharmacopeia has recently initiated two new general chapters to provide advice for researchers and manufacturers in the vaccine and virology fields and beyond. Chapter 1235 Vaccines and Vaccine Test Methods will focus on manufacturing and analytical requirements for the different types of vaccines currently in manufacture and development. Chapter 1237 Virology Test Methods will discuss modern diagnostic virology techniques and a variety of tests as applicable to vaccine and biologics manufacturing.

  19. 12 CFR 347.105 - Permissible financial activities outside the United States.

    Science.gov (United States)

    2010-01-01

    ... consulting services, provided that such services when rendered with respect to the domestic market must be... REGULATIONS AND STATEMENTS OF GENERAL POLICY INTERNATIONAL BANKING § 347.105 Permissible financial activities... and credit health insurance. (6) Performing services for other direct or indirect operations of...

  20. Properties of human motor units after prolonged activity at a constant firing rate.

    Science.gov (United States)

    Johnson, K V B; Edwards, S C; Van Tongeren, C; Bawa, P

    2004-02-01

    The primary purpose of this study was to examine if there are changes in the intrinsic properties of spinal motoneurons after prolonged submaximal contractions. To do this, we assessed whether or not the synaptic drive to motoneurons needs to increase in order to maintain a constant firing rate of a motor unit. Recruitment of new units and an increase in total electromyographic (EMG) activity of the muscle of interest were taken as estimates of an increase in synaptic drive. Subjects were asked to maintain a constant firing rate of a clearly identifiable (targeted) motor unit from the first dorsal interosseous muscle for approximately 10 min, while surface EMG and force were recorded simultaneously. For the 60 units studied, the duration of the constant-firing-rate period ranged from 73 to 1,140 s (448 +/- 227 s; mean +/- SD). There was a significant increase ( t-test, prate suggesting an increase in the net excitatory input to the motoneuron pool. Changes occurring simultaneously in other parameters, namely, variability in interspike interval, magnitude of force fluctuations, the duration of motor unit action potentials, and the median power frequency of surface EMG were also computed. The firing rates of 16 concurrently firing motoneurons, not controlled by the subject, remained constant. The key finding of this study is that after prolonged activity, a motoneuron requires a stronger excitatory input to maintain its firing rate. Additional results are indicative of significant changes in the characteristics of the synaptic inputs, changes at the neuromuscular junction (both pre- and postsynaptic regions) and the sarcolemma.

  1. 75 FR 39045 - New United Motor Manufacturing, Inc., Formerly a Joint Venture of General Motors Corporation and...

    Science.gov (United States)

    2010-07-07

    ... General Motors Corporation and Toyota Motor Corporation, Including On- Site Leased Workers From Corestaff, ABM Janitorial, Toyota Engineering and Manufacturing North America, and NPA Coatings, Inc., and On... Manufacturing, Inc., formerly a joint ] venture of General Motors Corporation and Toyota Motor...

  2. Inflammatory cytokines in general and central obesity and modulating effects of physical activity.

    Directory of Open Access Journals (Sweden)

    Frank M Schmidt

    Full Text Available Chronic systemic inflammation in obesity originates from local immune responses in visceral adipose tissue. However, assessment of a broad range of inflammation-mediating cytokines and their relationship to physical activity and adipometrics has scarcely been reported to date.To characterize the profile of a broad range of pro- and anti-inflammatory cytokines and the impact of physical activity and energy expenditure in individuals with general obesity, central obesity, and non-obese subjects.A cross-sectional study comprising 117 obese patients (body mass index (BMI ≥ 30 and 83 non-obese community-based volunteers.Serum levels of interleukin (IL-2, IL-4, IL-5, IL-10, IL-12, IL-13, granulocyte-macrophage colony-stimulating factor (GM-CSF, interferon (IFN-γ and tumor necrosis factor (TNF-α were measured. Physical activity and energy expenditure (MET were assessed with actigraphy. Adipometrics comprised BMI, weight, abdominal-, waist- and hip-circumference, waist to hip ratio (WHR, and waist-to-height-ratio (WHtR.General obesity was associated with significantly elevated levels of IL-5, IL-10, IL-12, IL-13, IFN-γ and TNF-α, central obesity with significantly elevated IL-5, IL-10, IL-12, IL-13 and IFN-γ-levels. In participants with general obesity, levels of IL-4, IL-10 and IL-13 were significantly elevated in participants with low physical activity, even when controlled for BMI which was negatively associated with physical acitivity. Cytokines significantly correlated with adipometrics, particularly in obese participants.Results confirm up-regulation of certain pro- and anti-inflammatory cytokines in obesity. In obese subjects, physical activity may lower levels and thus reduce pro-inflammatory effects of cytokines that may link obesity, insulin resistance and diabetes.

  3. Does an activity based remuneration system attract young doctors to general practice?

    Directory of Open Access Journals (Sweden)

    Abelsen Birgit

    2012-03-01

    Full Text Available Abstract Background The use of increasingly complex payment schemes in primary care may represent a barrier to recruiting general practitioners (GP. The existing Norwegian remuneration system is fully activity based - 2/3 fee-for-service and 1/3 capitation. Given that the system has been designed and revised in close collaborations with the medical association, it is likely to correspond - at least to some degree - with the preferences of current GPs (men in majority. The objective of this paper was to study which preferences that young doctors (women in majority, who are the potential entrants to general practice have for activity based vs. salary based payment systems. Methods In November-December 2010 all last year medical students and all interns in Norway (n = 1.562 were invited to participate in an online survey. The respondents were asked their opinion on systems of remuneration for GPs; inclination to work as a GP; risk attitude; income preferences; work pace tolerance. The data was analysed using one-way ANOVA and multinomial logistic regression analysis. Results A total of 831 (53% responded. Nearly half the sample (47% did not consider the remuneration system to be important for their inclination to work as GP; 36% considered the current system to make general practice more attractive, while 17% considered it to make general practice less attractive. Those who are attracted by the existing system were men and those who think high income is important, while those who are deterred by the system are risk averse and less happy with a high work pace. On the question of preferred remuneration system, half the sample preferred a mix of salary and activity based remuneration (the median respondent would prefer a 50/50 mix. Only 20% preferred a fully activity based system like the existing one. A salary system was preferred by women, and those less concerned with high income, while a fully activity based system was preferred by men, and those

  4. Cutaneous responsiveness of rat single motor units activated by natural stimulation.

    Science.gov (United States)

    Solano, R; Herrero, J F

    1997-05-16

    Recordings of withdrawal reflexes have been used extensively to study sensory-motor integration and processing of nociceptive information in the spinal cord. We describe here a new technique for the manufacture of improved EMG electrodes that permit the characterisation of the physiological properties of single motor units as well as the easy location of the muscles studied. Individual motor units from three rat hind-limb muscles: peroneus longus, tibialis cranialis and extensor digitorum longus, were activated by thermal and mechanical stimulation applied to their cutaneous receptive fields, which were located mainly on the 4th and 5th toes. Thresholds for thermal and mechanical (Von Frey hairs) stimulation were similar in the three muscles studied, with a value of 44 +/- 1 degrees C and 100 mN (median), respectively. However, when a mechanical pincher with a stimulus area of 14 mm2 was used, the values seen were similar for peroneus longus and tibialis cranialis (342 +/- 23 and 330 +/- 71 mN, respectively, mean +/- S.E.M.) but lower for extensor digitorum longus (220 +/- 37 mN, mean +/- S.E.M.). The firing rate of the single motor units was similar for all types of stimulation at threshold intensity, and showed a linear relationship with stimulus intensity, except for units of the tibialis cranialis, which showed a greater degree of adaptation.

  5. CONFIGURING THE ROLE OF THE UNITED NATIONS SECRETARYGENERAL IN THE PEACEFUL SETTLEMENT OF INTERNATIONAL DISPUTES. RELATIONS WITH THE SECURITY COUNCIL AND THE GENERAL ASSEMBLY

    Directory of Open Access Journals (Sweden)

    OANA-ADRIANA IACOB

    2012-05-01

    Full Text Available In an international context embracing the idealist concepts of harmony, cooperation, structural peace, illegality of war, the United Nations Organization has created a system of peaceful settlement of disputes, based on principles of justice and international law. In this framework, the organs bearing the responsibility of peaceful resolution of conflicts are the International Court of Justice, the Security Council, the General Assembly and the Secretary-General. The latter has a unique position, triggering a spectacular evolution of its role in the maintenance of international peace and security. The challenges of the international environment and the outstanding ways in which they were addressed by the distinctive personalities that filled the function of the Secretary General, creating precedents and influencing its future development, have led to a continuous enlargement of its role. The purpose of the present paper is that of defining the role of the Secretary-General in the system of peaceful settlement of international disputes created by the United Nations, by analysing the relevant provisions consecrated in the Charter and by revealing and explaining the outstanding evolution of this institution, with an emphasis on the relations of mutual influence between the High Official, on one side, the Security Council and the General Assembly, on the other.

  6. Active FEL-Klystrons As Formers of Femto-Second Clusters of Electromagnetic Field. General Description

    Directory of Open Access Journals (Sweden)

    A.Ju. Brusnik

    2010-01-01

    Full Text Available A qualitative physical and technological substantiation of the creation possibility of a new class of Femto-second Free Electron Lasers (FFELs (active cluster FEL-klystrons is given in the article. The concept of “electromagnetic field” cluster is introduced. Apart from that, the main difference between the concepts “the electromagnetic cluster” and “the radio-pulse” (which is well-known in radio-physics is formulated. The concept of “cluster electromagnetic wave” is also discussed. A general approach to designing the proposed active cluster FEL-klystrons is formulated. The description of a principal design scheme of the active cluster FEL-klystrons and their key technological basis are discussed.

  7. Motor competence and physical activity in 8-year-old school children with generalized joint hypermobility

    DEFF Research Database (Denmark)

    Juul-Kristensen, Birgit; Kristensen, Jens Halkjaer; Frausing, Britt;

    2009-01-01

    were clinically examined and tested for motor competence, whereas questionnaire response to items comprising musculoskeletal pain and injuries, in addition to daily level and duration of physical activity, corresponded to 377 (71.9%) children. RESULTS: In total, 29% of the children had GJH4, 19% had...... regarding motor competence, self-reported physical activity, and incidence of musculoskeletal pain and injuries. METHODS: A cross-sectional study of 524 children in the second grade from 10 public schools was performed. A positive response rate was obtained for 416 (79.4%) children, and 411 (78.4%) children......OBJECTIVE: Because the criteria used for diagnosing between generalized joint hypermobility (GJH) and musculoskeletal complaints, as well as relations between GJH and an insufficient motor development and/or a reduced physical activity level differ, the prevalence of GJH varies considerably...

  8. 75 FR 28656 - New United Motor Manufacturing, Inc., Formerly a Joint Venture of General Motors Corporation, and...

    Science.gov (United States)

    2010-05-21

    ... General Motors Corporation, and Toyota Motor Corporation, Including On- Site Leased Workers From Corestaff, ABM Janitorial, and Toyota Engineering and Manufacturing North America, Fremont, CA; Amended... and Toyota Motor Corporation, including on-site leased workers from Corestaff and ABM...

  9. Effect of Cellular Phone and Radar Forensics on Search and Rescue Duration for General Aviation Aircraft Accidents in the Contiguous United States

    OpenAIRE

    Wallace, Ryan J

    2014-01-01

    Emergency Locator Transmitters (ELT) are generally the primary tool for locating distressed aircrews following an aircraft accident. In 2009, the International COSPAS-SARSAT organization ordered the cessation of 121.5 MHz ELT satellite monitoring to alleviate systemic false alarms and encourage pilots to upgrade ELTs to modern 406 MHz models. While most nations acquiesced to the mandate, the United States encountered severe resistance from pilot groups. As a result, 121.5 MHz ELTs are still i...

  10. IPN - Orsay Report of activity 1998-1999. General activities. Technical Development; IPN - Orsay. Rapport d'activite 1998-1999. Activites generales. Recherches techniques

    Energy Technology Data Exchange (ETDEWEB)

    Pouthas, Joel; Hutin, Christiane; Rivenez, Jean-Philippe [eds.] [Institut de Physique Nucleaire, 91406 Orsay cedex (France)

    2000-01-12

    ALICE dimuon spectrometer and for HADES experiment. Also the progress in developing the equipment for G0 experiment, VAMOS spectrometer, the large surface annular telescope and EUROBALL 4 detector is described. Finally in the chapter four there are reported works on developing a peak sensing ADC, a VXI D size card for EXOGAM,and data acquisition systems. The first volume begins with short reports of activity from the technical and general servicing departments. The second volume of the IPNO Report presents the results of the Research Division.

  11. Activation of hypoxia inducible factor 1 is a general phenomenon in infections with human pathogens.

    Directory of Open Access Journals (Sweden)

    Nadine Werth

    Full Text Available BACKGROUND: Hypoxia inducible factor (HIF-1 is the key transcriptional factor involved in the adaptation process of cells and organisms to hypoxia. Recent findings suggest that HIF-1 plays also a crucial role in inflammatory and infectious diseases. METHODOLOGY/PRINCIPAL FINDINGS: Using patient skin biopsies, cell culture and murine infection models, HIF-1 activation was determined by immunohistochemistry, immunoblotting and reporter gene assays and was linked to cellular oxygen consumption. The course of a S. aureus peritonitis was determined upon pharmacological HIF-1 inhibition. Activation of HIF-1 was detectable (i in all ex vivo in biopsies of patients suffering from skin infections, (ii in vitro using cell culture infection models and (iii in vivo using murine intravenous and peritoneal S. aureus infection models. HIF-1 activation by human pathogens was induced by oxygen-dependent mechanisms. Small colony variants (SCVs of S. aureus known to cause chronic infections did not result in cellular hypoxia nor in HIF-1 activation. Pharmaceutical inhibition of HIF-1 activation resulted in increased survival rates of mice suffering from a S. aureus peritonitis. CONCLUSIONS/SIGNIFICANCE: Activation of HIF-1 is a general phenomenon in infections with human pathogenic bacteria, viruses, fungi and protozoa. HIF-1-regulated pathways might be an attractive target to modulate the course of life-threatening infections.

  12. Signature for a partership between CERN and Israel - His Excellency Mr Itzhak Levanon, Ambassador, Permanent Representative of Israel to the Unite Nations Office and specialized institutions in Geneva and Mr Robert Aymar, CERN Director General

    CERN Multimedia

    Maximilien Brice

    2004-01-01

    On 29 November 2004, the Israeli ambassador to the United Nations Office at Geneva, Itzhak Levanon, and CERN's director-general, Robert Aymar, signed a new protocol to the Co-operation Agreement between the government of Israel and CERN. This protocol covers a substantial increase in the Israeli contribution to CERN's Large Hadron Collider (LHC) Project. Israeli scientists have been participating in CERN's scientific activities since 1960, and in 1992 Israel became the first non-member state to make regular financial contributions to CERN's budget.

  13. Mortality of induced abortion, other outpatient surgical procedures and common activities in the United States.

    Science.gov (United States)

    Raymond, Elizabeth G; Grossman, Daniel; Weaver, Mark A; Toti, Stephanie; Winikoff, Beverly

    2014-11-01

    The recent surge of new legislation regulating induced abortion in the United States is ostensibly motivated by the desire to protect women's health. To provide context for interpreting the risk of abortion, we compared abortion-related mortality to mortality associated with other outpatient surgical procedures and selected nonmedical activities. We calculated the abortion-related mortality rate during 2000-2009 using national data. We searched PubMed and other sources for contemporaneous data on mortality associated with other outpatient procedures commonly performed on healthy young women, marathon running, bicycling and driving. The abortion-related mortality rate in 2000-2009 in the United States was 0.7 per 100,000 abortions. Studies in approximately the same years found mortality rates of 0.8-1.7 deaths per 100,000 plastic surgery procedures, 0-1.7deaths per 100,000 dental procedures, 0.6-1.2 deaths per 100,000 marathons run and at least 4 deaths among 100,000 cyclists in a large annual bicycling event. The traffic fatality rate per 758 vehicle miles traveled by passenger cars in the United States in 2007-2011 was about equal to the abortion-related mortality rate. The safety of induced abortion as practiced in the United States for the past decade met or exceeded expectations for outpatient surgical procedures and compared favorably to that of two common nonmedical voluntary activities. The new legislation restricting abortion is unnecessary; indeed, by reducing the geographic distribution of abortion providers and requiring women to travel farther for the procedure, these laws are potentially detrimental to women's health. Copyright © 2014 Elsevier Inc. All rights reserved.

  14. Motor unit activity during isometric and concentric-eccentric contractions of the human first dorsal interosseus muscle.

    Science.gov (United States)

    Howell, J N; Fuglevand, A J; Walsh, M L; Bigland-Ritchie, B

    1995-08-01

    1. Motor unit activity was recorded with intramuscular fine wire electrodes during isometric, concentric, and eccentric activity in the human first dorsal interosseus muscle. Twenty-one units from 11 subjects were sampled. 2. During isotonic cycles of shortening and lengthening, 18 of 21 units were recruited during the concentric phase, increased their discharge rates as the concentric movement progressed, then decreased their discharge rate during the eccentric phase, and were derecruited. 3. A different pattern of recruitment was observed in recordings from three units. These units were recruited during the eccentric phase, at a time when other units were decreasing their discharge rate or being derecruited. In two of the units selectively recruited during the eccentric phase, it was possible to determine their isometric thresholds, which were higher than those of units exhibiting the more common pattern of recruitment. 4. For two of the three units exhibiting selective recruitment during eccentric contraction, the unit was recorded simultaneously with different pairs of recording wires separated by 5-10 mm. Each discharge of these units was detected by both electrodes, making it unlikely that movement artifact was responsible for the initiation or cessation of discharge. 5. The recruitment patterns observed suggest that changes in the type or distribution of synaptic inputs to motoneurons during movement can, in some instances, override pre- and postsynaptic factors that shape recruitment order in isometric conditions.

  15. Generalized proportional integral control for periodic signals under active disturbance rejection approach.

    Science.gov (United States)

    Cortés-Romero, John; Ramos, Germán A; Coral-Enriquez, Horacio

    2014-11-01

    Conventional repetitive control has proven to be an effective strategy to reject/track periodic signals with constant frequency; however, it shows poor performance in varying frequency applications. This paper proposes an active disturbance rejection methodology applied to a large class of uncertain flat systems for the tracking and rejection of periodic signals, in which the possibilities of the generalized proportional integral (GPI) observer-based control to address repetitive control problems are studied. In the proposed scheme, model uncertainties and external disturbances are lumped together in a general additive disturbance input that is estimated and rejected on-line. An illustrative case study of mechatronic nature is considered. Experimental results show that the proposed GPI observer-based control successfully rejects periodic disturbances even under varying speed conditions.

  16. In vitro activities of nontraditional antimicrobials against multiresistant Acinetobacter baumannii strains isolated in an intensive care unit outbreak.

    Science.gov (United States)

    Appleman, M D; Belzberg, H; Citron, D M; Heseltine, P N; Yellin, A E; Murray, J; Berne, T V

    2000-04-01

    Fifteen multiresistant Acinetobacter baumannii isolates from patients in intensive care units and 14 nonoutbreak strains were tested to determine in vitro activities of nontraditional antimicrobials, including cefepime, meropenem, netilmicin, azithromycin, doxycycline, rifampin, sulbactam, and trovafloxacin. The latter five drugs were further tested against four of the strains for bactericidal or bacteriostatic activity by performing kill-curve studies at 0.5, 1, 2, and 4 times their MICs. In addition, novel combinations of drugs with sulbactam were examined for synergistic interactions by using a checkerboard configuration. MICs at which 90% of the isolates tested were inhibited for antimicrobials showing activity against the multiresistant A. baumannii strains were as follows (in parentheses): doxycycline (1 microg/ml), azithromycin (4 microg/ml), netilmicin (1 microg/ml), rifampin (8 microg/ml), polymyxin (0.8 U/ml), meropenem (4 microg/ml), trovafloxacin (4 microg/ml), and sulbactam (8 microg/ml). In the kill-curve studies, azithromycin and rifampin were rapidly bactericidal while sulbactam was more slowly bactericidal. Trovafloxacin and doxycycline were bacteriostatic. None of the antimicrobials tested were bactericidal against all strains tested. The synergy studies demonstrated that the combinations of sulbactam with azithromycin, rifampin, doxycycline, or trovafloxacin were generally additive or indifferent.

  17. Physical Activity and Reported Barriers to Activity Among Type 2 Diabetic Patients in the United Arab Emirates

    Science.gov (United States)

    Al-Kaabi, Juma; Al-Maskari, Fatma; Afandi, Bachar; Parkar, Hasratali; Nagelkerke, Nicolaas

    2009-01-01

    OBJECTIVES: This study was designed to assess the physical activity practice among type 2 diabetic patients in the United Arab Emirates (UAE). METHODS: This is a cross-sectional study of type 2 diabetic patients who participated in the outpatient clinics in Al-Ain District, during 2006. The patients completed an interviewer-administered questionnaire, and measurements of blood pressure, body mass index, body fat, abdominal circumference, glycemic control (HbA1c), and fasting lipid profile. RESULTS: Of the 390 patients recruited, only 25% reported an increase in their physical activity levels following the diagnosis of diabetes, and only 3% reported physical activity levels that meet the recommended guidelines. More than half of the study subjects had uncontrolled hypertension (53%) and unacceptable lipid profiles; 71% had a high low-density lipoprotein (LDL), 73% had low high-density lipoprotein (HDL), and 59% had hypertriglyceridemia. Forty-four percent were obese and a further 34% were overweight. Abdominal obesity was also common (59%). Only 32% had an acceptable glycemic control. CONCLUSIONS: The physical activity practice of type 2 diabetic patients in the UAE is largely inadequate to meet the recommended level necessary to prevent or ameliorate diabetic complications. Interventions aiming at overcoming the barriers to physical activity are urgently needed. PMID:20043039

  18. Design, Synthesis, Activity and Docking Study of Sorafenib Analogs Bearing Sulfonylurea Unit.

    Science.gov (United States)

    Wu, Chunjiang; Wang, Min; Tang, Qidong; Luo, Rong; Chen, Le; Zheng, Pengwu; Zhu, Wufu

    2015-10-23

    Two series of novel sorafenib analogs containing a sulfonylurea unit were synthesized and their chemical structures were confirmed by ¹H-NMR, ¹³C-NMR, MS spectrum and elemental analysis. The synthesized compounds were evaluated for the cytotoxicity against A549, Hela, MCF-7, and PC-3 cancer cell lines. Some of the compounds showed moderate cytotoxic activity, especially compounds 1-(2,4-difluorophenylsulfonyl)-3-(4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenyl)urea (6c) and 1-(4-bromophenylsulfonyl)-3-(4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenyl)urea (6f) with the IC50 values against four cancer cell lines ranging from 16.54±1.22 to 63.92±1.81 μM, respectively. Inhibitory rates against vascular endothelial growth factor receptor-2 (VEGFR2/KDR) kinase at 10 μM of target compounds were further carried out in this paper in order to investigate the target of these compounds. Structure-activity relationships (SARs) and docking studies indicated that the sulfonylurea unit was important to these kinds of compounds. None of the substitutions in the phenoxy group and small halogen atoms such as 2,4-difluoro substitution of the aryl group contributed to the activity. The results suggested that sulfonylurea sorafenib analogs are worthy of further study.

  19. Orthogeriatric activity in a general hospital of Castilla-La Mancha, Spain.

    Science.gov (United States)

    Fernández-Ibáñez, J M; Morales-Ballesteros, M C; Crespo-Romero, E; Gómez-Gómez, S; Fraga-Fuentes, M D; Cruz-Tejado, J; Hernández-Zegarra, P A; Arias-Arias, Á; García-Baltasar, M M

    To describe the orthogeriatric activity in the elderly with hip fractures in the Hospital Mancha Centro, based on the recommendations of the main guidelines. Observational prospective study, comprising all patients over 65 years of age admitted to the Traumatology Unit with a hip fracture between April 2015 and December 2015. Patients were admitted under the care of the Traumatology Unit with cross-consultation carried out with the Geriatrics Department, which then carried out a pre-operative geriatric assessment and the post-operative follow-ups. The mean pre-surgery waiting time was 48h and the overall time in hospital was 10.3±8.2 days. Patients who suffered from delirium (42.1%) did not improve as well, and were referred to nursing homes. Blood transfusions were received by 54.7% of the patients, despite 53.5% of them having received intravenous and/or oral iron after the surgery. Treatment with calcium and vitamin D was prescribed in 79% of the patients on discharge. The Rehabilitation Unit assessed 36% of the patients, with 4.8% fully, and 16.7% partially recovering their prior functional status. Upon discharge, 55% of the patients returned to their homes, and 22% were referred to short-term assisted living facilities. This article describes how the main clinical problems are handled in the elderly with hip fractures in our hospital, based on recommendations of the main guidelines and publications. Our hospital follows the recommended guidelines. Aspects for improvement include the management of anaemia during admission and rehabilitation. Copyright © 2017 SECOT. Publicado por Elsevier España, S.L.U. All rights reserved.

  20. 78 FR 12676 - Timing Requirements for the Submission of a Site Assessment Plan (SAP) or General Activities Plan...

    Science.gov (United States)

    2013-02-25

    ... Submission of a Site Assessment Plan (SAP) or General Activities Plan (GAP) for a Renewable Energy Project on... Assessment Plan (SAP) or General Activities Plan (GAP) pursuant to the regulations governing renewable energy... lessee or grantee must submit a SAP or a GAP. BOEM is taking this action because the current regulations...

  1. Experience with the pectoralis major myocutaneous flap for head and neck reconstruction in a general surgical unit.

    Directory of Open Access Journals (Sweden)

    Nagral S

    1992-07-01

    Full Text Available The pectoralis major myocutaneous (PMMC flap or its modification was used in 19 cases after resectional surgery for malignancy of the oral cavity with minimal morbidity and no mortality. The resection as well as reconstruction was done by the same team consisting only of general surgeons. The final functional and cosmetic results were satisfactory. The pectoralis major myocutaneous flap is a hardy flap and can be performed with relative ease even by those not specialised in plastic surgery. This makes it an important tool for a general surgeon practicing in a country like India with its high incidence of head and neck malignancy.

  2. Active generalized predictive control of turbine tip clearance for aero-engines

    Institute of Scientific and Technical Information of China (English)

    Peng Kai; Fan Ding; Yang Fan; Fu Qiang; Li Yong

    2013-01-01

    Active control of turbine blade tip clearance continues to be a concern in design and con-trol of gas turbines. Ever increasing demands for improved efficiency and higher operating temper-atures require more stringent tolerances on turbine tip clearance. In this paper, a turbine tip clearance control apparatus and a model of turbine tip clearance are proposed;an implicit active generalized predictive control (GPC), with auto-regressive (AR) error modification and fuzzy adjustment on control horizon, is presented, as well as a quantitative analysis method of robust per-turbation radius of the system. The active clearance control (ACC) of aero-engine turbine tip clear-ance is evaluated in a lapse-rate take-off transient, along with the comparative and quantitative analysis of the stability and robustness of the active tip clearance control system. The results show that the resultant active tip clearance control system with the improved GPC has favorable steady-state and dynamic performance and benefits of increased efficiency, reduced specific fuel consump-tion, and additional service life.

  3. User experience network. Supply gas failure alarm on Cardinal Health Infant Flow SiPAP units may not activate.

    Science.gov (United States)

    2009-07-01

    The supply gas failure alarm on Cardinal Health Infant Flow SiPAP units manufactured before April 2009 may not activate in the event of a gas supply loss if the device's silencer accessory is attached. However, the unit's FiO2 (fraction of inspired oxygen) and low-airway-pressure alarms will activate in such cases. If both of these alarms activate simultaneously, users should suspect a failure of the gas supply pressure. Identifying affected units requires testing that can be conducted during the device's next scheduled maintenance.

  4. Gifted and General High School Students' Perceptions of Learning and Motivational Constructs in Korea and the United States

    Science.gov (United States)

    Chae, Yoojung; Gentry, Marcia

    2011-01-01

    This study examined differences between Korean and US gifted and general students' perceptions constructs related to motivation and learning, using the Student Perceptions of Classroom Quality (SPOCQ) instrument. SPOCQ assesses students' perceptions of appeal, challenge, choice, meaningfulness, and academic self-efficacy. Measurement equality…

  5. Effect of Advanced Location Methods on Search and Rescue Duration for General Aviation Aircraft Accidents in the Contiguous United States

    Science.gov (United States)

    Wallace, Ryan J.

    2013-01-01

    The purpose of this study was to determine the impact of advanced search and rescue devices and techniques on search duration for general aviation aircraft crashes. The study assessed three categories of emergency locator transmitters, including 121.5 MHz, 406 MHz, and GPS-Assisted 406 MHz devices. The impact of the COSPAS-SARSAT organization…

  6. 75 FR 26794 - New United Motor Manufacturing, Inc., Formerly a Joint Venture of General Motors Corporation and...

    Science.gov (United States)

    2010-05-12

    ... Motor Manufacturing, Inc., Formerly a Joint Venture of General Motors Corporation and Toyota Motor... and Toyota Motor Corporation, including on-site leased workers from Corestaff, Fremont, California... assemble the Toyota Corolla and the Toyota Tacoma and used to assemble the Pontiac Vibe. The...

  7. Intensified dust storm activity and Valley fever infection in the southwestern United States

    Science.gov (United States)

    Tong, Daniel Q.; Wang, Julian X. L.; Gill, Thomas E.; Lei, Hang; Wang, Binyu

    2017-05-01

    Climate models have consistently projected a drying trend in the southwestern United States, aiding speculation of increasing dust storms in this region. Long-term climatology is essential to documenting the dust trend and its response to climate variability. We have reconstructed long-term dust climatology in the western United States, based on a comprehensive dust identification method and continuous aerosol observations from the Interagency Monitoring of Protected Visual Environments (IMPROVE) network. We report here direct evidence of rapid intensification of dust storm activity over American deserts in the past decades (1988-2011), in contrast to reported decreasing trends in Asia and Africa. The frequency of windblown dust storms has increased 240% from 1990s to 2000s. This dust trend is associated with large-scale variations of sea surface temperature in the Pacific Ocean, with the strongest correlation with the Pacific Decadal Oscillation. We further investigate the relationship between dust and Valley fever, a fast-rising infectious disease caused by inhaling soil-dwelling fungus (Coccidioides immitis and C. posadasii) in the southwestern United States. The frequency of dust storms is found to be correlated with Valley fever incidences, with a coefficient (r) comparable to or stronger than that with other factors believed to control the disease in two endemic centers (Maricopa and Pima County, Arizona).

  8. Activities of the Climate Forecast Unit (CFU) on regional decadal prediction

    Science.gov (United States)

    Guemas, V.; Prodhomme, C.; Doblas-Reyes, F.; Volpi, D.; Caron, L. P.; Davis, M.; Menegoz, M.; Saurral, R. I.; Bellprat, O.

    2014-12-01

    The Climate Forecasting Unit (CFU) is a research unit devoted to develop climate forecast systems to contribute to the creation of climate services that aims to 1) develop climate forecast systems and prediction methodologies, 2) investigate the potential sources of skill and understand the limitation of state-of-the-art forecast systems, 3) formulate reliable climate forecasts that meet specific user needs and 4) contribute to the development of climate services. This presentation will provide an overview of the latest results of this research unit in the field of regional decadal prediction focusing on 1) an assessment of the relative merits of the full-field and the anomaly initialisation techniques, 2) a description of the forecast quality of North Atlantic tropical cyclone activity and South Pacific climate, 3) an evaluation of the impact of volcanic aerosol prescription during decadal forecasts, and 4) the strategy for the development of a climate service to ensure that forecasts are both useful and action-oriented. Results from several European projects, SPECS, PREFACE and EUPORIAS, will be used to illustrate these findings.

  9. QSAR study on estrogenic activity of structurally diverse compounds using generalized regression neural network

    Institute of Scientific and Technical Information of China (English)

    JI Li; WANG XiaoDong; LUO Si; QIN Liang; YANG XvShu; LIU ShuShen; WANG LianSheng

    2008-01-01

    Computer-based quantitative structure-activity relationship (QSAR) model has been becoming a powerful tool in understanding the structural requirements for chemicals to bind the estrogen receptor (ER), designing drugs for human estrogen replacement therapy, and identifying potential estrogenic endocrine disruptors, in this study, a simple yet powerful neural network technique, generalized regression neural network (GRNN) was used to develop a QSAR model based on 131 structurally diverse estrogens (training set). Only nine descriptors calculated solely from the molecular structures of compounds selected by objective and subjective feature selections were used as inputs of the GRNN model. The predictive power of the built model was found to be comparable to that of the more traditional techniques but requiring significantly easy implementation and a shorter computation-time. The obtained result indicates that the proposed GRNN model is robust and satisfactory, and can provide a feasible and practical tool for the rapid screening of the estrogenic activity of organic compounds.

  10. A Comparison between the American Institute of Architects’ and the United States Navy’s Construction Contract General Provisions

    Science.gov (United States)

    1992-01-01

    SCOTT A. HAYWARD CT MARO0 119935 A REPORT PRESENTED TO THE GRADUATE COMMITTEE OF THE DEPARTMENT OF CIVIL ENGINEERING IN PARTIAL FULFILLMENT OF THE...an officer of the Civil Engineer Corps, United States Navy or another officer or representative of the Government, as Resident Officer in Charge of...Awlo 9 ay dfll it C nt bcor mahflP" U _ L3.7.. 7A.3.3. nooposa Arhiec Owe Arhiec Contrato ACbntratioor relo..nc cnt Oed~e prepared NOrnobl4 Becme

  11. Boron Stress Activates the General Amino Acid Control Mechanism and Inhibits Protein Synthesis

    Science.gov (United States)

    Uluisik, Irem; Kaya, Alaattin; Fomenko, Dmitri E.; Karakaya, Huseyin C.; Carlson, Bradley A.; Gladyshev, Vadim N.; Koc, Ahmet

    2011-01-01

    Boron is an essential micronutrient for plants, and it is beneficial for animals. However, at high concentrations boron is toxic to cells although the mechanism of this toxicity is not known. Atr1 has recently been identified as a boron efflux pump whose expression is upregulated in response to boron treatment. Here, we found that the expression of ATR1 is associated with expression of genes involved in amino acid biosynthesis. These mechanisms are strictly controlled by the transcription factor Gcn4 in response to boron treatment. Further analyses have shown that boron impaired protein synthesis by promoting phosphorylation of eIF2α in a Gcn2 kinase dependent manner. The uncharged tRNA binding domain (HisRS) of Gcn2 is necessary for the phosphorylation of eIF2α in the presence of boron. We postulate that boron exerts its toxic effect through activation of the general amino acid control system and inhibition of protein synthesis. Since the general amino acid control pathway is conserved among eukaryotes, this mechanism of boron toxicity may be of general importance. PMID:22114689

  12. Boron stress activates the general amino acid control mechanism and inhibits protein synthesis.

    Directory of Open Access Journals (Sweden)

    Irem Uluisik

    Full Text Available Boron is an essential micronutrient for plants, and it is beneficial for animals. However, at high concentrations boron is toxic to cells although the mechanism of this toxicity is not known. Atr1 has recently been identified as a boron efflux pump whose expression is upregulated in response to boron treatment. Here, we found that the expression of ATR1 is associated with expression of genes involved in amino acid biosynthesis. These mechanisms are strictly controlled by the transcription factor Gcn4 in response to boron treatment. Further analyses have shown that boron impaired protein synthesis by promoting phosphorylation of eIF2α in a Gcn2 kinase dependent manner. The uncharged tRNA binding domain (HisRS of Gcn2 is necessary for the phosphorylation of eIF2α in the presence of boron. We postulate that boron exerts its toxic effect through activation of the general amino acid control system and inhibition of protein synthesis. Since the general amino acid control pathway is conserved among eukaryotes, this mechanism of boron toxicity may be of general importance.

  13. Answers to frequently asked questions about cleanup activities at Three Mile Island, Unit 2. Public information report

    Energy Technology Data Exchange (ETDEWEB)

    1980-09-01

    The document presents answers to frequently asked questions about plans for cleanup and decontamination activities at Three Mile Island, Unit 2. Answers to the questions asked are based on information in the NRC 'Draft Programmatic Environmental Impact Statement related to decontamination and disposal of radioactive wastes resulting from March 28, 1979, accident, Three Mile Island Nuclear Station, Unit 2,' NUREG-0683.

  14. Leprosy in Buriticupu, state of Maranhão: active search in the general population

    Directory of Open Access Journals (Sweden)

    Antonio Rafael da Silva

    2012-04-01

    Full Text Available INTRODUCTION: This study was developed to evaluate the situation of leprosy in the general population of the municipality of Buriticupu, State of Maranhão, Brazil. METHODS: We used the method of active search to identify new cases from 2008 to 2010. Bacilloscopy of intradermal scrapings was performed in all patients with skin lesions compatible with leprosy, and histopathological examination in those who had doubts on the definition of the clinical form. RESULTS: The study included 19,104 individuals, with 42 patients diagnosed with leprosy after clinical examination, representing a detection rate of 219.84 per 100,000 inhabitants. The predominant clinical presentation was tuberculoid with 24 (57.1% cases, followed by borderline with 11, indeterminate with four, and lepromatous with three cases. The study also allowed the identification of 81 patients with a history of leprosy and other skin diseases, such as pityriasis versicolor, dermatophytosis, scabies, vitiligo, and skin carcinoma. The binomial test showed that the proportion of cases in the headquarters was significantly higher than that in the villages (p = 0.04, and the generalized exact test showed that there was no association between age and clinical form (p = 0.438 and between age and gender (p = 0.083. CONCLUSIONS: The elevated detection rate defines the city as hyperendemic for leprosy; the active search for cases, as well as the organization of health services, is an important method for disease control.

  15. Prevalence of fruit and vegetable consumption and physical activity by race/ethnicity--United States, 2005.

    Science.gov (United States)

    2007-04-06

    Diets high in fruits and vegetables and participation in regular physical activity are associated with a lower risk for several chronic diseases and conditions. The National Cholesterol Education Program and the American Cancer Society both emphasize lifestyle modifications that include diet and physical activity to reduce disease risk. These are also two of the strategies implemented by states participating in CDC's Nutrition and Physical Activity Program to Prevent Obesity and Other Chronic Diseases. To examine the combined prevalence of 1) consumption of fruits and vegetables five or more times per day and 2) regular physical activity among U.S. adults by race/ethnicity, CDC analyzed self-reported data from the 2005 Behavioral Risk Factor Surveillance System (BRFSS). This report describes the results of that analysis, which indicated that the combined prevalence of these two behavioral strategies was higher among men of multiple/other races (16.5%) compared with non-Hispanic white men (12.6%). In addition, only 12.6% of non-Hispanic black women and 14.8% of Hispanic women, compared with 17.4% of non-Hispanic white women, engaged in these two behavioral strategies. These results underscore the need to promote diets high in fruits and vegetables and regular physical activity among all populations in the United States and among racial and ethnic minority communities in particular.

  16. Annual and seasonal tornado activity in the United States and the global wind oscillation

    Science.gov (United States)

    Moore, Todd W.

    2017-08-01

    Previous studies have searched for relationships between tornado activity and atmospheric teleconnections to provide insight on the relationship between tornadoes, their environments, and larger scale patterns in the climate system. Knowledge of these relationships is practical because it can improve seasonal and sub-seasonal predictions of tornado probability and, therefore, help mitigate tornado-related losses. This study explores the relationships between the annual and seasonal tornado activity in the United States and the Global Wind Oscillation. Time series herein show that phases of the Global Wind Oscillation, and atmospheric angular momentum anomalies, vary over a period of roughly 20-25 years. Rank correlations indicate that tornado activity is weakly correlated with phases 2, 3, and 4 (positive) and 6, 7, and 8 (negative) of the Global Wind Oscillation in winter, spring, and fall. The correlation is not as clear in summer or at the annual scale. Non-parametric Mann-Whitney U tests indicate that winters and springs with more phase 2, 3, and 4 and fewer phase 6, 7, and 8 days tend to have more tornadoes. Lastly, logistic regression models indicate that winters and springs with more phase 2, 3, and 4 days have greater likelihoods of having more than normal tornado activity. Combined, these analyses suggest that seasons with more low atmospheric angular momentum days, or phase 2, 3, and 4 days, tend to have greater tornado activity than those with fewer days, and that this relationship is most evident in winter and spring.

  17. Knowledge of carbohydrate counting and insulin dose calculations among hospital staff in a regional general paediatrics unit.

    Science.gov (United States)

    O'Gorman, Jennifer R; O'Leary, Orla; Finner, Natalie; Quinn, Anne; O'Gorman, Clodagh S

    2015-01-01

    The aim of this study was to assess the carbohydrate and insulin knowledge of the staff at Children's Ark at the University Hospital, Limerick. Carbohydrate counting and insulin dose calculations based on carbohydrates and blood sugars are integral to intensive insulin management of type 1 diabetes mellitus (T1DM). The PedCarbQuiz, a validated questionnaire, was modified, and applied to the staff on our general paediatrics ward. 48/70 eligible staff responded (rate 68 %). Overall knowledge was good: 75.5 % was the average score for correctly identifying foods containing carbohydrate. However, poor scores were obtained for calculating multiple items and meal values (average score 29 %), and exact values of insulin required (average score 38 %). These results highlight the need for re-education among staff on a general paediatrics ward, to empower ward staff to contribute effectively to the education and management of patients with T1DM.

  18. USAWC (United States Army War College) Military Studies Program Paper. The Development of the American General Staff: 1880 to 1920

    Science.gov (United States)

    2007-11-02

    of a general staff, reasons for such an organization, and the actual develorinent of the staff compared to the design. After the Amnerican Civil War...organization, and the actual development of the staff compared to the design. After the American Civil War a group of reformers assessed the performance of...and prohib- ited it from interfering with the bureaus and their administration. The bureau chiefs regarded the Act as their "Magna Carta " essentially

  19. Cross-cultural comparisons of attitudes toward schizophrenia amongst the general population and physicians: a series of web-based surveys in Japan and the United States.

    Science.gov (United States)

    Richards, Misty; Hori, Hiroaki; Sartorius, Norman; Kunugi, Hiroshi

    2014-02-28

    Cross-cultural differences in attitudes toward schizophrenia are suggested, while no studies have compared such attitudes between the United States and Japan. In our previous study in Japan (Hori et al., 2011), 197 subjects in the general population and 112 physicians (excluding psychiatrists) enrolled in a web-based survey using an Internet-based questionnaire format. Utilizing the identical web-based survey method in the United States, the present study enrolled 172 subjects in the general population and 45 physicians. Participants' attitudes toward schizophrenia were assessed with the English version of the 18-item questionnaire used in our previous Japanese survey. Using exploratory factor analysis, we identified four factors labeled "social distance," "belief of dangerousness," "underestimation of patients' abilities," and "skepticism regarding treatment." The two-way multivariate analysis of covariance on the four factors, with country and occupation as the between-subject factors and with potentially confounding demographic variables as the covariates, revealed that the general population in the US scored significantly lower than the Japanese counterparts on the factors "social distance" and "skepticism regarding treatment" and higher on "underestimation of patients' abilities." Our results suggest that culture may have an important role in shaping attitudes toward mental illness. Anti-stigma campaigns that target culture-specific biases are considered important.

  20. Accounting for medical variation: the case of prescribing activity in a New Zealand general practice sample.

    Science.gov (United States)

    Davis, P B; Yee, R L; Millar, J

    1994-08-01

    Medical practice variation is extensive and well documented, particularly for surgical interventions, and raises important questions for health policy. To date, however, little work has been carried out on interpractitioner variation in prescribing activity in the primary care setting. An analytical model of medical variation is derived from the literature and relevant indicators are identified from a study of New Zealand general practice. The data are based on nearly 9,500 completed patient encounter records drawn from over a hundred practitioners in the Waikato region of the North Island, New Zealand. The data set represents a 1% sample of all weekday general practice office encounters in the Hamilton Health District recorded over a 12-month period. Overall levels of prescribing, and the distribution of drug mentions across diagnostic groupings, are broadly comparable to results drawn from international benchmark data. A multivariate analysis is carried out on seven measures of activity in the areas of prescribing volume, script detail, and therapeutic choice. The analysis indicates that patient, practitioner and practice attributes exert little systematic influence on the prescribing task. The principal influences are diagnosis, followed by practitioner identity. The pattern of findings suggests also that the prescribing task cannot be viewed as an undifferentiated activity. It is more usefully considered as a process of decision-making in which 'core' judgements--such as the decision to prescribe and the choice of drug--are highly predictable and strongly influenced by diagnosis, while 'peripheral' features of the task--such as choosing a combination drug or prescribing generically--are less determinate and more subject to the exercise of clinical discretion.(ABSTRACT TRUNCATED AT 250 WORDS)

  1. Management and climate contributions to satellite-derived active fire trends in the contiguous United States

    Science.gov (United States)

    Lin, Hsiao-Wen; McCarty, Jessica L.; Wang, Dongdong; Rogers, Brendan M.; Morton, Douglas C.; Collatz, G. James; Jin, Yufang; Randerson, James T.

    2014-04-01

    Fires in croplands, plantations, and rangelands contribute significantly to fire emissions in the United States, yet are often overshadowed by wildland fires in efforts to develop inventories or estimate responses to climate change. Here we quantified decadal trends, interannual variability, and seasonality of Terra Moderate Resolution Imaging Spectroradiometer (MODIS) observations of active fires (thermal anomalies) as a function of management type in the contiguous U.S. during 2001-2010. We used the Monitoring Trends in Burn Severity database to identify active fires within the perimeter of large wildland fires and land cover maps to identify active fires in croplands. A third class of fires defined as prescribed/other included all residual satellite active fire detections. Large wildland fires were the most variable of all three fire types and had no significant annual trend in the contiguous U.S. during 2001-2010. Active fires in croplands, in contrast, increased at a rate of 3.4% per year. Cropland and prescribed/other fire types combined were responsible for 77% of the total active fire detections within the U.S and were most abundant in the south and southeast. In the west, cropland active fires decreased at a rate of 5.9% per year, likely in response to intensive air quality policies. Potential evaporation was a dominant regulator of the interannual variability of large wildland fires, but had a weaker influence on the other two fire types. Our analysis suggests it may be possible to modify landscape fire emissions within the U.S. by influencing the way fires are used in managed ecosystems.

  2. Compiling a register of patients with moderate or severe learning disabilities: experience at one United Kingdom general practice

    Science.gov (United States)

    2011-01-01

    Background Identifying patients with learning disabilities within primary care is central to initiatives for improving the health of this population. UK general practitioners (GPs) receive additional income for maintaining registers of patients with learning disabilities as part of the Quality and Outcomes Framework (QOF), and may opt to provide Directed Enhanced Services (DES), which requires practices to maintain registers of patients with moderate or severe learning disabilities and offer them annual health checks. Objectives This paper describes the development of a register of patients with moderate or severe learning disabilities at one UK general practice. Methods A Read code search of one UK general practice's electronic medical records was conducted in order to identify patients with learning disabilities. Confirmation of diagnoses was sought by scrutinising records and GP verification. Cross-referencing with the practice QOF register of patients with learning disabilities of any severity, and the local authority's list of clients with learning disabilities, was performed. Results Of 15 001 patients, 229 (1.5%) were identified by the Read code search as possibly having learning disabilities. Scrutiny of records and GP verification confirmed 64 had learning disabilities and 24 did not, but the presence or absence of learning disability remained unclear in 141 cases. Cross-referencing with the QOF register (n=81) and local authority list (n=49) revealed little overlap. Conclusion Identifying learning disability and assessing its severity are tasks GPs may be unfamiliar with, and relying on Read code searches may result in under-detection. Further research is needed to define optimum strategies for identifying, cross-referencing and validating practice-based registers of patients with learning disabilities. PMID:22479290

  3. Compiling a register of patients with moderate or severe learning disabilities: experience at one United Kingdom general practice.

    Science.gov (United States)

    Lodge, Keri-Michèle; Milnes, David; Gilbody, Simon M

    2011-03-01

    Background Identifying patients with learning disabilities within primary care is central to initiatives for improving the health of this population. UK general practitioners (GPs) receive additional income for maintaining registers of patients with learning disabilities as part of the Quality and Outcomes Framework (QOF), and may opt to provide Directed Enhanced Services (DES), which requires practices to maintain registers of patients with moderate or severe learning disabilities and offer them annual health checks.Objectives This paper describes the development of a register of patients with moderate or severe learning disabilities at one UK general practice.Methods A Read code search of one UK general practice's electronic medical records was conducted in order to identify patients with learning disabilities. Confirmation of diagnoses was sought by scrutinising records and GP verification. Cross-referencing with the practice QOF register of patients with learning disabilities of any severity, and the local authority's list of clients with learning disabilities, was performed.Results Of 15 001 patients, 229 (1.5%) were identified by the Read code search as possibly having learning disabilities. Scrutiny of records and GP verification confirmed 64 had learning disabilities and 24 did not, but the presence or absence of learning disability remained unclear in 141 cases. Cross-referencing with the QOF register (n=81) and local authority list (n=49) revealed little overlap.Conclusion Identifying learning disability and assessing its severity are tasks GPs may be unfamiliar with, and relying on Read code searches may result in under-detection. Further research is needed to define optimum strategies for identifying, cross-referencing and validating practice-based registers of patients with learning disabilities.

  4. Hippocampal and Cerebellar Single-Unit Activity During Delay and Trace Eyeblink Conditioning in the Rat

    Science.gov (United States)

    Green, John T.; Arenos, Jeremy D.

    2007-01-01

    In delay eyeblink conditioning, the CS overlaps with the US and only a brainstem-cerebellar circuit is necessary for learning. In trace eyeblink conditioning, the CS ends before the US is delivered and several forebrain structures, including the hippocampus, are required for learning, in addition to a brainstem-cerebellar circuit. The interstimulus interval (ISI) between CS onset and US onset is perhaps the most important factor in classical conditioning, but studies comparing delay and trace conditioning have typically not matched these procedures in this crucial factor, so it is often difficult to determine whether results are due to differences between delay and trace or to differences in ISI. In the current study, we employed a 580-ms CS-US interval for both delay and trace conditioning and compared hippocampal CA1 activity and cerebellar interpositus nucleus activity in order to determine whether a unique signature of trace conditioning exists in patterns of single-unit activity in either structure. Long-Evans rats were chronically implanted in either CA1 or interpositus with microwire electrodes and underwent either delay eyeblink conditioning, or trace eyeblink conditioning with a 300-ms trace period between CS offset and US onset. On trials with a CR in delay conditioning, CA1 pyramidal cells showed increases in activation (relative to a pre-CS baseline) during the CS-US period in sessions 1-4 that was attenuated by sessions 5-6. In contrast, on trials with a CR in trace conditioning, CA1 pyramidal cells did not show increases in activation during the CS-US period until sessions 5-6. In sessions 5-6, increases in activation were present only to the CS and not during the trace period. For rats with interpositus electrodes, activation of interpositus neurons on CR trials was present in all sessions in both delay and trace conditioning. However, activation was greater in trace compared to delay conditioning in the first half of the CS-US interval (during the

  5. Lower respiratory tract infection hospitalizations among American Indian/Alaska Native children and the general United States child population

    Directory of Open Access Journals (Sweden)

    Eric M. Foote

    2015-11-01

    Full Text Available Background: The lower respiratory tract infection (LRTI-associated hospitalization rate in American Indian and Alaska Native (AI/AN children aged <5 years declined during 1998–2008, yet remained 1.6 times higher than the general US child population in 2006–2008. Purpose: Describe the change in LRTI-associated hospitalization rates for AI/AN children and for the general US child population aged <5 years. Methods: A retrospective analysis of hospitalizations with discharge ICD-9-CM codes for LRTI for AI/AN children and for the general US child population <5 years during 2009–2011 was conducted using Indian Health Service direct and contract care inpatient data and the Nationwide Inpatient Sample, respectively. We calculated hospitalization rates and made comparisons to previously published 1998–1999 rates prior to pneumococcal conjugate vaccine introduction. Results: The average annual LRTI-associated hospitalization rate declined from 1998–1999 to 2009–2011 in AI/AN (35%, p<0.01 and the general US child population (19%, SE: 4.5%, p<0.01. The 2009–2011 AI/AN child average annual LRTI-associated hospitalization rate was 20.7 per 1,000, 1.5 times higher than the US child rate (13.7 95% CI: 12.6–14.8. The Alaska (38.9 and Southwest regions (27.3 had the highest rates. The disparity was greatest for infant (<1 year pneumonia-associated and 2009–2010 H1N1 influenza-associated hospitalizations. Conclusions: Although the LRTI-associated hospitalization rate declined, the 2009–2011 AI/AN child rate remained higher than the US child rate, especially in the Alaska and Southwest regions. The residual disparity is likely multi-factorial and partly related to household crowding, indoor smoke exposure, lack of piped water and poverty. Implementation of interventions proven to reduce LRTI is needed among AI/AN children.

  6. [Community vegetable gardens as a health promotion activity: an experience in Primary Healthcare Units].

    Science.gov (United States)

    Costa, Christiane Gasparini Araújo; Garcia, Mariana Tarricone; Ribeiro, Silvana Maria; Salandini, Marcia Fernanda de Sousa; Bógus, Cláudia Maria

    2015-10-01

    Urban and peri-urban agriculture (UPA) is being practiced in different settings, contributing to the improvement of health in communities and healthier environments. In order to identify the meanings and implications of the practice of UPA in Primary Healthcare Units (PHU) as an activity of health promotion (HP), and to what extent its therapeutic dimension characterizes it as an activity aligned with complementary and integrative practices (CIP), a qualitative cross-sectional study was performed in Embu das Artes, State of São Paulo. From the analysis, the following main themes arose: health concept, health outcomes, the return to traditional practices and habits and the reorientation of health services. It was possible to identify the close link between the cultivation of vegetable gardens and HP guidelines and fields of action, such as creating healthier environments, boosting community actions, developing personal skills, stimulating autonomy and empowerment and demands for the reorientation of services. The garden activities, set up in PHU areas, proved to be an implementation strategy of CIP. The conclusion reached is that vegetable gardening activities in community gardens are seen to be health promotion practices that integrate key elements of CIP.

  7. Acute two-photon imaging of the neurovascular unit in the cortex of active mice

    Science.gov (United States)

    Tran, Cam Ha T.; Gordon, Grant R.

    2015-01-01

    In vivo two-photon scanning fluorescence imaging is a powerful technique to observe physiological processes from the millimeter to the micron scale in the intact animal. In neuroscience research, a common approach is to install an acute cranial window and head bar to explore neocortical function under anesthesia before inflammation peaks from the surgery. However, there are few detailed acute protocols for head-restrained and fully awake animal imaging of the neurovascular unit during activity. This is because acutely performed awake experiments are typically untenable when the animal is naïve to the imaging apparatus. Here we detail a method that achieves acute, deep-tissue two-photon imaging of neocortical astrocytes and microvasculature in behaving mice. A week prior to experimentation, implantation of the head bar alone allows mice to train for head-immobilization on an easy-to-learn air-supported ball treadmill. Following just two brief familiarization sessions to the treadmill on separate days, an acute cranial window can subsequently be installed for immediate imaging. We demonstrate how running and whisking data can be captured simultaneously with two-photon fluorescence signals with acceptable movement artifacts during active motion. We also show possible applications of this technique by (1) monitoring dynamic changes to microvascular diameter and red blood cells in response to vibrissa sensory stimulation, (2) examining responses of the cerebral microcirculation to the systemic delivery of pharmacological agents using a tail artery cannula during awake imaging, and (3) measuring Ca2+ signals from synthetic and genetically encoded Ca2+ indicators in astrocytes. This method will facilitate acute two-photon fluorescence imaging in awake, active mice and help link cellular events within the neurovascular unit to behavior. PMID:25698926

  8. Acute two-photon imaging of the neurovascular unit in the cortex of active mice

    Directory of Open Access Journals (Sweden)

    Cam Ha Thai Tran

    2015-02-01

    Full Text Available In vivo two-photon scanning fluorescence imaging is a powerful technique to observe physiological processes from the millimeter to the micron scale in the intact animal. In neuroscience research, a common approach is to install an acute cranial window and head bar to explore neocortical function under anesthesia before inflammation peaks from the surgery. However, there are few detailed acute protocols for head-restrained and fully awake animal imaging of the neurovascular unit during activity. This is because acutely performed awake experiments are typically untenable when the animal is naïve to the imaging apparatus. Here we detail a protocol that achieves acute, deep-tissue two-photon imaging of neocortical astrocytes and microvasculature in behaving mice. A week prior to experimentation, implantation of the head bar alone allows mice to train for head-immobilization on an easy-to-learn air-supported ball treadmill. Following just two brief familiarization sessions to the treadmill on separate days, an acute cranial window can subsequently be installed for immediate imaging. We demonstrate how running and whisking data can be captured simultaneously with two-photon fluorescence signals with acceptable movement artifacts during active motion. We also show possible applications of this technique by 1 monitoring dynamic changes to microvascular diameter and red blood cells movements in response to vibrissa sensory stimulation, 2 examining responses of the cerebral microcirculation to the systemic delivery of pharmacological agents using a tail artery cannula during awake imaging, and 3 measuring Ca2+ signals from synthetic and genetically encoded Ca2+ indicators in astrocytes. This method will facilitate acute two-photon fluorescence imaging in awake, active mice and help link cellular events within the neurovascular unit to behaviour.

  9. Volume of activity and occupancy rate in intensive care units. Association with mortality.

    Science.gov (United States)

    Iapichino, Gaetano; Gattinoni, Luciano; Radrizzani, Danilo; Simini, Bruno; Bertolini, Guido; Ferla, Luca; Mistraletti, Giovanni; Porta, Francesca; Miranda, Dinis R

    2004-02-01

    Mortality after many procedures is lower in centers where more procedures are done. It is controversial whether this is true for intensive care units, too. We examined the relationship between the volume of activity of intensive care units (ICUs) and mortality by a measure of risk-adjusted volume of activity specific for ICUs. Prospective, multicenter, observational study. Eighty-nine ICUs in 12 European countries. During a 4-month study period, 12,615 patients were enrolled. Demographic and clinical statistics, severity at admission and a score of nursing complexity and workload were collected. Total volume of activity was defined as the number of patients admitted per bed per year, high-risk volume as the number of high-risk patients admitted per bed per year (selected combining of length of stay and severity of illness). A multi-step risk-adjustment process was planned. ICU volume corresponding both to overall [odds ratio (OR) 0.966] and 3,838 high-risk (OR 0.830) patients was negatively correlated with mortality. Relative mortality decreased by 3.4 and 17.0% for every five extra patients treated per bed per year in overall volume and high-risk volume, respectively. A direct relationship was found between mortality and the ICU occupancy rate (OR 1.324 and 1.351, respectively). Intensive care patients, whatever their level of risk, are best treated where more high-risk patients are treated. Moreover, the higher the ICU occupancy rate, the higher is the mortality.

  10. A Prediction on the Unit Cost Estimation for Decommissioning Activities Using the Experienced Data from DECOMMIS

    Energy Technology Data Exchange (ETDEWEB)

    Park, Seung Kook; Park, Hee Seong; Choi, Yoon Dong; Song, Chan Ho; Moon, Jei Kwon [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2014-05-15

    The KAERI (Korea Atomic Energy Research Institute) has developed the DECOMMIS (Decommissioning Information Management System) and have been applied for the decommissioning project of the KRR (Korea Research Reactor)-1 and 2 and UCP (Uranium Conversion Plant), as the meaning of the first decommissioning project in Korea. All information and data which are from the decommissioning activities are input, saved, output and managed in the DECOMMIS. This system was consists of the web server and the database server. The users could be access through a web page, depending on the input, processing and output, and be modified the permissions to do such activities can after the decommissioning activities have created the initial system-wide data is stored. When it could be used the experienced data from DECOMMIS, the cost estimation on the new facilities for the decommissioning planning will be established with the basic frame of the WBS structures and its codes. In this paper, the prediction on the cost estimation through using the experienced data which were store in DECOMMIS was studied. For the new decommissioning project on the nuclear facilities in the future, through this paper, the cost estimation for the decommissioning using the experienced data which were WBS codes, unit-work productivity factors and annual governmental unit labor cost is proposed. These data were from the KRR and UCP decommissioning project. The differences on the WBS code sectors and facility characterization between new objected components and experienced dismantled components was reduces as scaling factors. The study on the establishment the scaling factors and cost prediction for the cost estimation is developing with the algorithms from the productivity data, now.

  11. A generalized finite difference method for modeling cardiac electrical activation on arbitrary, irregular computational meshes.

    Science.gov (United States)

    Trew, Mark L; Smaill, Bruce H; Bullivant, David P; Hunter, Peter J; Pullan, Andrew J

    2005-12-01

    A generalized finite difference (GFD) method is presented that can be used to solve the bi-domain equations modeling cardiac electrical activity. Classical finite difference methods have been applied by many researchers to the bi-domain equations. However, these methods suffer from the limitation of requiring computational meshes that are structured and orthogonal. Finite element or finite volume methods enable the bi-domain equations to be solved on unstructured meshes, although implementations of such methods do not always cater for meshes with varying element topology. The GFD method solves the bi-domain equations on arbitrary and irregular computational meshes without any need to specify element basis functions. The method is useful as it can be easily applied to activation problems using existing meshes that have originally been created for use by finite element or finite difference methods. In addition, the GFD method employs an innovative approach to enforcing nodal and non-nodal boundary conditions. The GFD method performs effectively for a range of two and three-dimensional test problems and when computing bi-domain electrical activation moving through a fully anisotropic three-dimensional model of canine ventricles.

  12. General cell-binding activity of intramolecular G-quadruplexes with parallel structure.

    Science.gov (United States)

    Chang, Tianjun; Qi, Cui; Meng, Jie; Zhang, Nan; Bing, Tao; Yang, Xianda; Cao, Zehui; Shangguan, Dihua

    2013-01-01

    G-quadruplexes (G4s) are four-stranded nucleic acid structures adopted by some repetitive guanine-rich sequences. Putative G-quadruplex-forming sequences (PQSs) are highly prevalent in human genome. Recently some G4s have been reported to have cancer-selective antiproliferative activity. A G4 DNA, AS1411, is currently in phase II clinical trials as an anticancer agent, which is reported to bind tumor cells by targeting surface nucleolin. AS1411 also has been extensively investigated as a target-recognition element for cancer cell specific drug delivery or cancer cell imaging. Here we show that, in addition to AS1411, intramolecular G4s with parallel structure (including PQSs in genes) have general binding activity to many cell lines with different affinity. The binding of these G4s compete with each other, and their targets are certain cellular surface proteins. The tested G4s exhibit enhanced cellular uptake than non-G4 sequences. This uptake may be through the endosome/lysosome pathway, but it is independent of cellular binding of the G4s. The tested G4s also show selective antiproliferative activity that is independent of their cellular binding. Our findings provide new insight into the molecular recognition of G4s by cells; offer new clues for understanding the functions of G4s in vivo, and may extend the potential applications of G4s.

  13. General cell-binding activity of intramolecular G-quadruplexes with parallel structure.

    Directory of Open Access Journals (Sweden)

    Tianjun Chang

    Full Text Available G-quadruplexes (G4s are four-stranded nucleic acid structures adopted by some repetitive guanine-rich sequences. Putative G-quadruplex-forming sequences (PQSs are highly prevalent in human genome. Recently some G4s have been reported to have cancer-selective antiproliferative activity. A G4 DNA, AS1411, is currently in phase II clinical trials as an anticancer agent, which is reported to bind tumor cells by targeting surface nucleolin. AS1411 also has been extensively investigated as a target-recognition element for cancer cell specific drug delivery or cancer cell imaging. Here we show that, in addition to AS1411, intramolecular G4s with parallel structure (including PQSs in genes have general binding activity to many cell lines with different affinity. The binding of these G4s compete with each other, and their targets are certain cellular surface proteins. The tested G4s exhibit enhanced cellular uptake than non-G4 sequences. This uptake may be through the endosome/lysosome pathway, but it is independent of cellular binding of the G4s. The tested G4s also show selective antiproliferative activity that is independent of their cellular binding. Our findings provide new insight into the molecular recognition of G4s by cells; offer new clues for understanding the functions of G4s in vivo, and may extend the potential applications of G4s.

  14. Optimization of a general-purpose, actively scanned proton beamline for ocular treatments: Geant4 simulations.

    Science.gov (United States)

    Piersimoni, Pierluigi; Rimoldi, Adele; Riccardi, Cristina; Pirola, Michele; Molinelli, Silvia; Ciocca, Mario

    2015-03-08

    The Italian National Center for Hadrontherapy (CNAO, Centro Nazionale di Adroterapia Oncologica), a synchrotron-based hospital facility, started the treatment of patients within selected clinical trials in late 2011 and 2012 with actively scanned proton and carbon ion beams, respectively. The activation of a new clinical protocol for the irradiation of uveal melanoma using the existing general-purpose proton beamline is foreseen for late 2014. Beam characteristics and patient treatment setup need to be tuned to meet the specific requirements for such a type of treatment technique. The aim of this study is to optimize the CNAO transport beamline by adding passive components and minimizing air gap to achieve the optimal conditions for ocular tumor irradiation. The CNAO setup with the active and passive components along the transport beamline, as well as a human eye-modeled detector also including a realistic target volume, were simulated using the Monte Carlo Geant4 toolkit. The strong reduction of the air gap between the nozzle and patient skin, as well as the insertion of a range shifter plus a patient-specific brass collimator at a short distance from the eye, were found to be effective tools to be implemented. In perspective, this simulation toolkit could also be used as a benchmark for future developments and testing purposes on commercial treatment planning systems.

  15. Utility Values for Advanced Soft Tissue Sarcoma Health States from the General Public in the United Kingdom

    Directory of Open Access Journals (Sweden)

    Julian F. Guest

    2013-01-01

    Full Text Available Soft tissue sarcomas are a rare type of cancer generally treated with palliative chemotherapy when in the advanced stage. There is a lack of published health utility data for locally advanced “inoperable”/metastatic disease (ASTS, essential for calculating the cost-effectiveness of current and future treatments. This study estimated time trade-off (TTO and standard gamble (SG preference values associated with four ASTS health states (progressive disease, stable disease, partial response, complete response among members of the general public in the UK (n=207. The four health states were associated with decreases in preference values from full health. Complete response was the most preferred health state (mean utility of 0.60 using TTO. The second most preferred health state was partial response followed by stable disease (mean utilities were 0.51 and 0.43, respectively, using TTO. The least preferred health state was progressive disease (mean utility of 0.30 using TTO. The utility value for each state was significantly different from one another (P<0.001. This study demonstrated and quantified the impact that different treatment responses may have on the health-related quality of life of patients with ASTS.

  16. Guaranteed Student Loans: Profits of Secondary Market Lenders Vary Widely. United States General Accounting Office Briefing Report to Congressional Requesters.

    Science.gov (United States)

    General Accounting Office, Washington, DC. Div. of Human Resources.

    This report was prepared to determine lenders' rates of return or profitability on Stafford loans in their portfolios, reasons for varying levels of profitability among institutions that hold such loans, and the effect of 1986 subsidy reductions on these lenders' profitability. The study focused on the activities of lenders that purchase Stafford…

  17. Unit Activity of Hippocampal Interneurons before Spontaneous Seizures in an Animal Model of Temporal Lobe Epilepsy.

    Science.gov (United States)

    Toyoda, Izumi; Fujita, Satoshi; Thamattoor, Ajoy K; Buckmaster, Paul S

    2015-04-22

    Mechanisms of seizure initiation are unclear. To evaluate the possible roles of inhibitory neurons, unit recordings were obtained in the dentate gyrus, CA3, CA1, and subiculum of epileptic pilocarpine-treated rats as they experienced spontaneous seizures. Most interneurons in the dentate gyrus, CA1, and subiculum increased their firing rate before seizures, and did so with significant consistency from seizure to seizure. Identification of CA1 interneuron subtypes based on firing characteristics during theta and sharp waves suggested that a parvalbumin-positive basket cell and putative bistratified cells, but not oriens lacunosum moleculare cells, were activated preictally. Preictal changes occurred much earlier than those described by most previous in vitro studies. Preictal activation of interneurons began earliest (>4 min before seizure onset), increased most, was most prevalent in the subiculum, and was minimal in CA3. Preictal inactivation of interneurons was most common in CA1 (27% of interneurons) and included a putative ivy cell and parvalbumin-positive basket cell. Increased or decreased preictal activity correlated with whether interneurons fired faster or slower, respectively, during theta activity. Theta waves were more likely to occur before seizure onset, and increased preictal firing of subicular interneurons correlated with theta activity. Preictal changes by other hippocampal interneurons were largely independent of theta waves. Within seconds of seizure onset, many interneurons displayed a brief pause in firing and a later, longer drop that was associated with reduced action potential amplitude. These findings suggest that many interneurons inactivate during seizures, most increase their activity preictally, but some fail to do so at the critical time before seizure onset.

  18. Position Paper of the People's Republic of China at the 66th Session of the United Nations General Assembly

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    1.The Role of the United Nations (UN) The word is undergoing major development,major changes and major adjustments.The trend of peace,development and cooperation is gaining momentum.Multi-polarity and economic globalization are deepening.New changes are taking place in global economic governance,and emerging economies are engaged in dynamic cooperation.All these have brought valuable opportunities to the development of all countries.On the other hand,the world still suffers from the underlying impact of the financial crisis.Global recovery is confronted with the uncertainties created by acute debt crisis,rising commodity prices and inflationary pressure around the world.In this context,major economies should continue to strengthen macroeconomic policy coordination so as to ensure strong,sustainable and balanced growth of the world economy.The international security situation has become more complex.Regional hotspot issues keep flaring up,and turbulence continues in West Asia and North Africa,Non-traditional security issues such as climate change,energy security,food security,terrorism and nuclear safety are becoming more pronounced.In sum,there are a growing array of destabilizing factors and uncertainties in the world and a long way to go before lasting peace and common development can be achieved.

  19. The Development of a General Purpose ARM-based Processing Unit for the TileCal sROD

    CERN Multimedia

    Cox, Mitchell A

    2014-01-01

    The Large Hadron Collider at CERN generates enormous amounts of raw data which present a serious computing challenge. After planned upgrades in 2022, the data output from the ATLAS Tile Calorimeter will increase by 200 times to 41 Tb/s! ARM processors are common in mobile devices due to their low cost, low energy consumption and high performance. It is proposed that a cost-effective, high data throughput Processing Unit (PU) can be developed by using several consumer ARM processors in a cluster configuration to allow aggregated processing performance and data throughput while maintaining minimal software design difficulty for the end-user. This PU could be used for a variety of high-level functions on the high-throughput raw data such as spectral analysis and histograms to detect possible issues in the detector at a low level. High-throughput I/O interfaces are not typical in consumer ARM System on Chips but high data throughput capabilities are feasible via the novel use of PCI-Express as the I/O interface t...

  20. The Development of a General Purpose ARM-based Processing Unit for the ATLAS TileCal sROD

    CERN Document Server

    Cox, Mitchell Arij; The ATLAS collaboration; Mellado Garcia, Bruce Rafael

    2015-01-01

    The Large Hadron Collider at CERN generates enormous amounts of raw data which present a serious computing challenge. After Phase-II upgrades in 2022, the data output from the ATLAS Tile Calorimeter will increase by 200 times to 41 Tb/s! ARM processors are common in mobile devices due to their low cost, low energy consumption and high performance. It is proposed that a cost-effective, high data throughput Processing Unit (PU) can be developed by using several consumer ARM processors in a cluster configuration to allow aggregated processing performance and data throughput while maintaining minimal software design difficulty for the end-user. This PU could be used for a variety of high-level functions on the high-throughput raw data such as spectral analysis and histograms to detect possible issues in the detector at a low level. High-throughput I/O interfaces are not typical in consumer ARM System on Chips but high data throughput capabilities are feasible via the novel use of PCI-Express as the I/O interface ...

  1. Maintaining connections: some thoughts on the value of intensive care unit rounding for general medicine ward teams.

    Science.gov (United States)

    Howell, Joel D

    2011-09-06

    When established ward patients are unexpectedly transferred to an intensive care unit (ICU), the ward team should continue to follow them. Although there may be reasons not to do so, the advantages outweigh the obstacles. Great pedagogic value can be gained from following patients after acute decompensation, but a more important reason is that by following patients into the ICU, the ward team can enact for both patients and their families the twin virtues of caring and continuity. Doing so also demonstrates the highest ideals of medicine-that we are focused not on defined areas of turf, but on our patient's well-being. It shows that we are not merely doing narrowly defined "shift work," but that we truly care about our patients. Rounding on established patients who have been transferred into the ICU is the sort of behavior that undergirds the fundamental bases of professionalism. It takes a few minutes from a busy day, but it can be incredibly beneficial for families, patients, and the ideals of medicine.

  2. cVEMP morphology changes with recording electrode position, but single motor unit activity remains constant.

    Science.gov (United States)

    Rosengren, Sally M; Colebatch, James G; Borire, Adeniyi; Straumann, Dominik; Weber, Konrad P

    2016-04-15

    Cervical vestibular evoked myogenic potentials (cVEMPs) recorded over the lower quarter of the sternocleidomastoid (SCM) muscle in normal subjects may have opposite polarity to those recorded over the midpoint. It has thus been suggested that vestibular projections to the lower part of SCM might be excitatory rather than inhibitory. We tested the hypothesis that the SCM muscle receives both inhibitory and excitatory vestibular inputs. We recorded cVEMPs in 10 normal subjects with surface electrodes placed at multiple sites along the anterior (sternal) component of the SCM muscle. We compared several reference sites: sternum, ipsilateral and contralateral earlobes, and contralateral wrist. In five subjects, single motor unit responses were recorded at the upper, middle, and lower parts of the SCM muscle using concentric needle electrodes. The surface cVEMP had the typical positive-negative polarity at the midpoint of the SCM muscle. In all subjects, as the recording electrode was moved toward each insertion point, p13 amplitude became smaller and p13 latency increased, then the polarity inverted to a negative-positive waveform (n1-p1). Changing the reference site did not affect reflex polarity. There was a significant short-latency change in activity in 61/63 single motor units, and in each case this was a decrease or gap in firing, indicating an inhibitory reflex. Single motor unit recordings showed that the reflex was inhibitory along the entire SCM muscle. The cVEMP surface waveform inversion near the mastoid and sternal insertion points likely reflects volume conduction of the potential occurring with increasing distance from the motor point.

  3. Parsec-scale Faraday Rotation Measures from General Relativistic MHD Simulations of Active Galactic Nuclei Jets

    CERN Document Server

    Broderick, Avery E

    2010-01-01

    For the first time it has become possible to compare global 3D general relativistic magnetohydrodynamic (GRMHD) jet formation simulations directly to very-long baseline interferometric multi-frequency polarization observations of the pc-scale structure of active galactic nucleus (AGN) jets. Unlike the jet emission, which requires post hoc modeling of the non-thermal electrons, the Faraday rotation measures (RMs) depend primarily upon simulated quantities and thus provide a robust way in which to confront simulations with observations. We compute RM distributions of 3D global GRMHD jet formation simulations, with which we explore the dependence upon model and observational parameters, emphasizing the signatures of structures generic to the theory of MHD jets. With typical parameters, we find that it is possible to reproduce the observed magnitudes and many of the structures found in AGN jet RMs, including the presence of transverse RM gradients. In our simulations the RMs are generated within a smooth extensio...

  4. Recognition of depression in children in general hospital-based paediatric units in Kenya: practice and policy implications

    Directory of Open Access Journals (Sweden)

    Mutiso Victoria N

    2009-10-01

    Full Text Available Abstract Background Physical disorders are commonly comorbid with depression in children attending general medical facilities. However, the depression component is rarely recognised. Methods A questionnaire on sociodemographics and history of presenting medical conditions was administered together with the Children's Depression Inventory (CDI to all 11-year-old to 17-year-old children attending at nine medical facilities. Results In all, 408 children were recruited from 9 health facilities. Whereas the clinicians diagnosed a mental disorder in only 2.5% of the sample studied, 41.3% had CDI scores that suggested mild to moderate depression. The highest proportion of children with depressive symptomatology was found at the Kenyatta National and Teaching Referral Hospital. Conclusion Although prevalence rate for depression among children is high, detection rates remain low. This finding has clinical practice and policy implications within and outside Kenya.

  5. Epidemiologic profile of otorhinolaryngological, head and neck disorders in a tertiary hospital unit in Greece: a challenge for general practitioners?

    Directory of Open Access Journals (Sweden)

    Rachiotis Georgios

    2006-06-01

    Full Text Available Abstract Background In Greece, primary care is still developing. The aim of this study was to define the epidemiologic profile of common otorhinolaryngological, head and neck disorders in order to help general practitioners to deal with them in a primary care future. Methods A total of 6771 patients attended the Otorhinolaryngology emergency department of the University General Hospital of Heraklion (Crete, between January and December 2004. All cases were included in this retrospective study. The registry of the Otorhinolaryngology emergency department was analysed and age, sex, seasonality and clinical diagnosis were tabulated. All patients were evaluated by Otorhinolaryngologists. The classification of the cases was based on the main symptom or clinical sign that conditioned the reason for seeking care. Diagnoses were also coded according to the International Classification of Diseases (ICD-10. Results The male to female ratio was 1:1. The mean age for females was 36.3 years standard deviation (SD: 21.1 and for males was 36.8 years (SD = 22.0. Eight hundred eighty six patients (13.1% formed the paediatric sub-group. Over 60% of the cases were classified in ten major groups of diagnosis. Acute tonsillitis (12.3% and acute pharyngitis (9.0% were the most common causes of all medical visits, followed by otitis media (7.6% and external ear canal obstruction by ear wax (6.2%. Oedema of the larynx was detected in 0.4%. A negative diagnosis of otorhinolaryngological, head and neck disorder was formulated in 553 patients (8.2%. Hospitalization rate was 5.2%. The highest rate of visits was registered in March. Conclusion Most patients used the facility as a primary care service. Real emergencies were a minority. Recovering data about which areas of Otorhinolaryngology deserve more emphasis might help primary health care providers to diagnose and manage the common otorhinolaryngological, head and neck disorders properly.

  6. A Preliminary Study on the Use of Mind Mapping as a Visual-Learning Strategy in General Education Science Classes for Arabic Speakers in the United Arab Emirates

    Science.gov (United States)

    Wilson, Kenesha; Copeland-Solas, Eddia; Guthrie-Dixon, Natalie

    2016-01-01

    Mind mapping was introduced as a culturally relevant pedagogy aimed at enhancing the teaching and learning experience in a general education, Environmental Science class for mostly Emirati English Language Learners (ELL). Anecdotal evidence suggests that the students are very artistic and visual and enjoy group-based activities. It was decided to…

  7. A General Methodology for Evaluation of Carbon Sequestration Activities and Carbon Credits

    Energy Technology Data Exchange (ETDEWEB)

    Klasson, KT

    2002-12-23

    A general methodology was developed for evaluation of carbon sequestration technologies. In this document, we provide a method that is quantitative, but is structured to give qualitative comparisons despite changes in detailed method parameters, i.e., it does not matter what ''grade'' a sequestration technology gets but a ''better'' technology should receive a better grade. To meet these objectives, we developed and elaborate on the following concepts: (1) All resources used in a sequestration activity should be reviewed by estimating the amount of greenhouse gas emissions for which they historically are responsible. We have done this by introducing a quantifier we term Full-Cycle Carbon Emissions, which is tied to the resource. (2) The future fate of sequestered carbon should be included in technology evaluations. We have addressed this by introducing a variable called Time-adjusted Value of Carbon Sequestration to weigh potential future releases of carbon, escaping the sequestered form. (3) The Figure of Merit of a sequestration technology should address the entire life-cycle of an activity. The figures of merit we have developed relate the investment made (carbon release during the construction phase) to the life-time sequestration capacity of the activity. To account for carbon flows that occur during different times of an activity we incorporate the Time Value of Carbon Flows. The methodology we have developed can be expanded to include financial, social, and long-term environmental aspects of a sequestration technology implementation. It does not rely on global atmospheric modeling efforts but is consistent with these efforts and could be combined with them.

  8. Barriers, facilitators and attitudes influencing health promotion activities in general practice: an explorative pilot study

    Directory of Open Access Journals (Sweden)

    Geense Wytske W

    2013-02-01

    Full Text Available Abstract Background The number of chronically ill patients increases every year. This is partly due to an unhealthy lifestyle. However, the frequency and quality of (evidence-based health promotion activities conducted by Dutch general practitioners (GPs and practice nurses (PNs are limited. The aim of this pilot study was to explore which lifestyle interventions Dutch GPs and PNs carry out in primary care, which barriers and facilitators can be identified and what main topics are with respect to attitudes towards health promoting activities. These topic areas will be identified for a future, larger scale study. Method This qualitative study consisted of 25 semi-structured interviews with sixteen GPs and nine PNs. ATLAS.ti was used to analyse the transcripts of the interviews. Results All GPs and PNs said they discuss lifestyle with their patients. Next to this, GPs and PNs counsel patients, and/or refer them to other disciplines. Only few said they refer patients to specific lifestyle programs or interventions in their own practice or in the neighbourhood. Several barriers and facilitators were identified. The main topics as barriers are: a lack of patients’ motivation to make lifestyle changes, insufficient reimbursement, a lack of proven effectiveness of interventions and a lack of overview of health promoting programs in their neighbourhood. The most cited facilitators are availability of a PN, collaboration with other disciplines and availability of interventions in their own practice. With respect to attitudes, six different types of GPs were identified reflecting the main topics that relate to attitudes, varying from ‘ignorer’ to ‘nurturer’. The topics relating to PNs attitudes towards health promotion activities, were almost unanimously positive. Conclusion GPs and PNs all say they discuss lifestyle issues with their patients, but the health promotion activities that are organized in their practice vary. Main topics that hinder

  9. Nursing activities score (NAS): a proposal for practical application in intensive care units.

    Science.gov (United States)

    Gonçalves, Leilane Andrade; Padilha, Katia Grillo; Cardoso Sousa, Regina M

    2007-12-01

    For over 30 years in an attempt to demonstrate the cost-benefit ratio of the intensive care unit (ICU) a variety of tools have been developed to measure not only the severity of illness of the patient but also to capture the true cost of nursing workload. In this context, the nursing activities score (NAS) was developed as a result of modifications to the therapeutic interventions scoring system-28 (TISS-28). The NAS is a tool to measure nursing workload ICU and it has been shown to be twice as effective in measuring how nurses spend their time caring for critically ill patients than the TISS-28. This paper discuss the introduction of the NAS into everyday use in an intensive care unit in Brazil and highlights the challenges of standardisation of operational definitions, training requirements and accurate completion of the documentation when using such a tool. The rationale and steps undertaken to achieve this are outlined and the benefits of such a process are highlighted.

  10. Individuality and adaptation across levels of selection: How shall we name and generalize the unit of Darwinism?

    Science.gov (United States)

    Gould, Stephen Jay; Lloyd, Elisabeth A.

    1999-01-01

    Two major clarifications have greatly abetted the understanding and fruitful expansion of the theory of natural selection in recent years: the acknowledgment that interactors, not replicators, constitute the causal unit of selection; and the recognition that interactors are Darwinian individuals, and that such individuals exist with potency at several levels of organization (genes, organisms, demes, and species in particular), thus engendering a rich hierarchical theory of selection in contrast with Darwin’s own emphasis on the organismic level. But a piece of the argument has been missing, and individuals at levels distinct from organisms have been denied potency (although granted existence within the undeniable logic of the theory), because they do not achieve individuality with the same devices used by organisms and therefore seem weak by comparison. We show here that different features define Darwinian individuality across scales of size and time. In particular, species-individuals may develop few emergent features as direct adaptations. The interactor approach works with emergent fitnesses, not with emergent features; and species, as a consequence of their different mechanism for achieving individuality (reproductive exclusivity among subparts, that is, among organisms), express many effects from other levels. Organisms, by contrast, suppress upwardly cascading effects, because the organismic style of individuality (by functional integration of subparts) does not permit much competition or differential reproduction of parts from within. Species do not suppress the operation of lower levels; such effects therefore become available as exaptations conferring emergent fitness—a primary source of the different strength that species achieve as effective Darwinian individuals in evolution. PMID:10518549

  11. Modeling and experimental testing activity of the Voltage Optimization Unit

    DEFF Research Database (Denmark)

    Zecchino, Antonio; Hu, Junjie; Marinelli, Mattia

    cost investments of to the system operator, thus a proactive tap algorithm is developed and tested in this project, relying on local measurements. In addition, we also compared the experimental result with the one simulated in the DigSilent PowerFactory software environment (the software used...... the voltage problems in presence of photovoltaic distributed generation, using Bistrup distribution grid (DONG Energy) as a test case. This second report presents the experimental results of the testing activity of the Voltage Optimization Unit (VOU), i.e., a distribution transformer with single-phase on......-load tap changers (OLTC) in an experimental low voltage grid. Both the transformer internal behavior and its effective operations under different unbalanced bidirectional power flow conditions have been investigated. Moreover, different control logics are analyzed based on their control objectives and control...

  12. Answers to frequently asked questions about cleanup activities at Three Mile Island, Unit 2

    Energy Technology Data Exchange (ETDEWEB)

    1984-03-01

    This question-and-answer report provides answers in nontechnical language to frequently asked questions about the status of cleanup activities at Three Mile Island, Unit 2. The answers update information first prepared in 1981, shortly after the cleanup got under way. Since then, a variety of important developments in the cleanup has occurred. The information in the report should be read in conjunction with NUREG 1060, a discussion of increased occupational exposure estimates for the cleanup. The questions and answers in this report cover purpose and community involvement, decontamination of water and reactor, fuel removal, radwaste transport, environmental impact, social and economic effects, worker exposures and safety, radiation monitoring, potential for accidents, and schedule and funding.

  13. Substantia nigra dopaminergic unit activity in behaving cats: effect of arousal on spontaneous discharge and sensory evoked activity.

    Science.gov (United States)

    Strecker, R E; Jacobs, B L

    1985-12-30

    Single-unit activity of dopaminergic neurons in the substantia nigra was recorded in freely moving cats during a variety of conditions designed to shed light on the hypotheses that these neurons are involved in the regulation of arousal-stress and/or selective attention. Both aversive and non-aversive arousing experimental conditions were used, including tail pinch, immersion of feet in ice-water, white noise, inaccessible food, feeding, grooming, inaccessible rats, and somatosensory stimulation. None of these conditions had an effect on tonic neuronal discharge rate. However, these neurons did exhibit brief excitatory and inhibitory responses to phasic auditory or visual stimuli presented when the cat was sitting quietly. These responses were dramatically attenuated if these stimuli were presented during the aforementioned conditions of behavioral arousal. This sharply contrasts with the inability of these same conditions to influence spontaneous discharge rate. The sensitivity of this neuronal sensory response to the concurrent behavioral condition supports the hypothesis that these neurons are involved in attentional processes or selective responding. The lack of responsiveness of these neurons to a variety of arousal/stress manipulations supports the hypothesis that dopaminergic neurons play a permissive, rather than an active, role in these processes.

  14. Survival and catabolic activity of natural and genetically engineered bacteria in a laboratory-scale activated-sludge unit

    Energy Technology Data Exchange (ETDEWEB)

    McClure, N.C.; Fry, J.C.; Weightman, A.J. (Univ. of Wales College of Cardiff (Wales))

    1991-02-01

    The survival of selected naturally occurring and genetically engineered bacteria in a fully functional laboratory-scale activated-sludge unit (ASU) was investigated. The effect of the presence of 3-chlorobenzoate (3CB) on the survival of Pseudomonas putida UWC1, with or without a chimeric plasmid, pD10, which encodes 3CB catabolism, was determined. P. putida UWC1(pD10) did not enhance 3CB breakdown in the ASU, even following inoculation at a high concentration (3 x 10(8) CFU/ml). The emergence of a natural, 3CB-degrading population appeared to have a detrimental effect on the survival of strain UWC1 in the ASU. The fate of two 3CB-utilizing bacteria, derived from activated-sludge microflora, was studied in experiments in which these strains were inoculated into the ASU. Both strains, AS2, an unmanipulated natural isolate which flocculated readily in liquid media, and P. putida ASR2.8, a transconjugant containing the recombinant plasmid pD10, survived for long periods in the ASU and enhanced 3CB breakdown at 15 degrees C. The results reported in this paper illustrate the importance of choosing strains which are well adapted to environmental conditions if the use of microbial inoculants for the breakdown of target pollutants is to be successful.

  15. The number of active motor units and their firing rates in voluntary contraction of human brachialis muscle.

    Science.gov (United States)

    Kanosue, K; Yoshida, M; Akazawa, K; Fujii, K

    1979-01-01

    To make clear the control mechanism of force generation in human muscle, the electrical activity of the brachialis muscle was studied at various levels of contraction force by recording single motor unit discharges as well as mass electromyograms (EMGs). The firing rate of motor units increased with force along an S-shaped curve. At low levels of force, motor units increased their firing rates steeply with force. At intermediate levels of force, each motor unit increased its firing rate linearly with force at lower rates. As the maximum of force was approached, the firing rate increased very steeply, reaching as high as 50 Hz or more. By applying a new method of statistical processing to mass EMGs, the number of active motor units and the size of action potential were estimated at each level of force. The number of active motor units increased monotonously with muscle force. Motor units recruited at high levels of force had larger amplitudes of action potentials than those recruited at lower levels. Calculations were made to determine how the relative contribution to an increase in muscle force is varied between recruitment and the increase in firing rate. The contribution of recruitment gradually decreased with the increase in force. Up to about 70% of the maximum force, recruitment is the major mechanism for increasing the force of contraction.

  16. Brigadier General James Stevens Simmons (1890-1954), Medical Corps, United States Army: a career in preventive medicine.

    Science.gov (United States)

    Marble, Sanders

    2012-02-01

    James Simmons began his career in the US Army as a laboratory officer and his assignments progressed into tropical medicine research. His interests and work evolved into preventive medicine (PM, as the Army termed public health), and he took both a PhD and a Doctorate in Public Health. As the Army's leading PM officer he was appointed head of PM in 1940 and guided the Army's PM effort through World War II. His responsibility ran from gas masks through healthy nutrition and occupational health to an enormous variety of diseases; by the war's end, the breadth and importance of PM was reflected in the Preventive Medicine Division, having fully one-sixth of all military personnel at the Surgeon General's Office. Simmons used his strong professional credentials to tap into civilian medicine for expertise the Army lacked and he established organizations that survive to this day. After retirement, he sought to expand the field of public health and raise another generation of public health physicians.

  17. Motor unit firing intervals and other parameters of electrical activity in normal and pathological muscle

    DEFF Research Database (Denmark)

    Fuglsang-Frederiksen, Anders; Smith, T; Høgenhaven, H

    1987-01-01

    The analysis of the firing intervals of motor units has been suggested as a diagnostic tool in patients with neuromuscular disorders. Part of the increase in number of turns seen in patients with myopathy could be secondary to the decrease in motor unit firing intervals at threshold force...... of the motor units, as noted in previous studies. In the brachial biceps muscle we have studied the firing intervals of 164 motor units in 14 controls, 140 motor units in 13 patients with myopathy and 86 motor units in 8 patients with neurogenic disorders, and related the findings to those of the turns...... analysis and the analysis of properties of individual motor unit potentials. To ensure comparable conditions we have examined motor unit firing intervals and turns at a force of 10% of maximum. The average of motor unit firing intervals and of interval variability was the same in controls and in patients...

  18. QSAR study on estrogenic activity of structurally diverse compounds using generalized regression neural network

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Computer-based quantitative structure-activity relationship (QSAR) model has been becoming a pow- erful tool in understanding the structural requirements for chemicals to bind the estrogen receptor (ER), designing drugs for human estrogen replacement therapy, and identifying potential estrogenic endo- crine disruptors. In this study, a simple yet powerful neural network technique, generalized regression neural network (GRNN) was used to develop a QSAR model based on 131 structurally diverse estro- gens (training set). Only nine descriptors calculated solely from the molecular structures of com- pounds selected by objective and subjective feature selections were used as inputs of the GRNN model. The predictive power of the built model was found to be comparable to that of the more traditional techniques but requiring significantly easy implementation and a shorter computation-time. The ob- tained result indicates that the proposed GRNN model is robust and satisfactory, and can provide a feasible and practical tool for the rapid screening of the estrogenic activity of organic compounds.

  19. Generalized Volterra kernel model identification of spike-timing-dependent plasticity from simulated spiking activity.

    Science.gov (United States)

    Robinson, Brian S; Song, Dong; Berger, Theodore W

    2014-01-01

    This paper presents a methodology to estimate a learning rule that governs activity-dependent plasticity from behaviorally recorded spiking events. To demonstrate this framework, we simulate a probabilistic spiking neuron with spike-timing-dependent plasticity (STDP) and estimate all model parameters from the simulated spiking data. In the neuron model, output spiking activity is generated by the combination of noise, feedback from the output, and an input-feedforward component whose magnitude is modulated by synaptic weight. The synaptic weight is calculated with STDP with the following features: (1) weight change based on the relative timing of input-output spike pairs, (2) prolonged plasticity induction, and (3) considerations for system stability. Estimation of all model parameters is achieved iteratively by formulating the model as a generalized linear model with Volterra kernels and basis function expansion. Successful estimation of all model parameters in this study demonstrates the feasibility of this approach for in-vivo experimental studies. Furthermore, the consideration of system stability and prolonged plasticity induction enhances the ability to capture how STDP affects a neural population's signal transformation properties over a realistic time course. Plasticity characterization with this estimation method could yield insights into functional implications of STDP and be incorporated into a cortical prosthesis.

  20. Physicochemical Properties, Biological Activity, Health Benefits, and General Limitations of Aged Black Garlic: A Review

    Directory of Open Access Journals (Sweden)

    Ji Hyeon Ryu

    2017-06-01

    Full Text Available Garlic (Allium sativum has been used as a medicinal food since ancient times. However, some people are reluctant to ingest raw garlic due to its unpleasant odor and taste. Therefore, many types of garlic preparations have been developed to reduce these attributes without losing biological functions. Aged black garlic (ABG is a garlic preparation with a sweet and sour taste and no strong odor. It has recently been introduced to Asian markets as a functional food. Extensive in vitro and in vivo studies have demonstrated that ABG has a variety of biological functions such as antioxidant, anti-inflammatory, anti-cancer, anti-obesity, anti-diabetic, anti-allergic, cardioprotective, and hepatoprotective effects. Recent studies have compared the biological activity and function of ABG to those of raw garlic. ABG shows lower anti-inflammatory, anti-coagulation, immunomodulatory, and anti-allergic effects compared to raw garlic. This paper reviews the physicochemical properties, biological activity, health benefits, adverse effects, and general limitations of ABG.

  1. Physicochemical Properties, Biological Activity, Health Benefits, and General Limitations of Aged Black Garlic: A Review.

    Science.gov (United States)

    Ryu, Ji Hyeon; Kang, Dawon

    2017-06-01

    Garlic (Allium sativum) has been used as a medicinal food since ancient times. However, some people are reluctant to ingest raw garlic due to its unpleasant odor and taste. Therefore, many types of garlic preparations have been developed to reduce these attributes without losing biological functions. Aged black garlic (ABG) is a garlic preparation with a sweet and sour taste and no strong odor. It has recently been introduced to Asian markets as a functional food. Extensive in vitro and in vivo studies have demonstrated that ABG has a variety of biological functions such as antioxidant, anti-inflammatory, anti-cancer, anti-obesity, anti-diabetic, anti-allergic, cardioprotective, and hepatoprotective effects. Recent studies have compared the biological activity and function of ABG to those of raw garlic. ABG shows lower anti-inflammatory, anti-coagulation, immunomodulatory, and anti-allergic effects compared to raw garlic. This paper reviews the physicochemical properties, biological activity, health benefits, adverse effects, and general limitations of ABG.

  2. Comparison of surgical outcomes among infants in neonatal intensive care units treated by pediatric surgeons versus general surgeons: The need for pediatric surgery specialists.

    Science.gov (United States)

    Boo, Yoon Jung; Lee, Eun Hee; Lee, Ji Sung

    2017-01-31

    This study compared the outcomes of infants who underwent surgery in neonatal intensive care units by pediatric surgeons and by general surgeons. This was a retrospective study of infants who underwent surgery in neonatal intensive care units between 2010 and 2014. A total of 227 patients were included. Of these patients, 116 were operated on by pediatric surgeons (PS) and 111 were operated on by general surgeons (GS). The outcome measures were the overall rate of operative complications, unplanned reoperation, mortality rate, length of stay, operative time, and number of total number of operative procedures. The overall operative complication rate was higher in the GS group compared with the PS group (18.7% vs. 7.0%, p=0.0091). The rate of unplanned reoperations was also higher in the GS group (10.8% vs. 3.5%, p=0.0331). The median operation time (90min vs. 75min, p=0.0474) and median length of stay (24days vs. 18days, p=0.0075) were significantly longer in the GS group. The adjusted odd ratios of postoperative complications for GS were 2.9 times higher than that of PS (OR 2.90, p=0.0352). The operative quality and patient outcomes of the PS group were superior to those of the GS group. III. Copyright © 2017 Elsevier Inc. All rights reserved.

  3. Association between long work hours and poor self-reported general health among Latin American immigrant and native workers in the United States and Spain.

    Science.gov (United States)

    Conway, Sadie H; Cayuela, Ana; Delclos, George L; Pompeii, Lisa A; Ronda, Elena

    2016-12-01

    The relationship between hours worked per week and self-reported general health (SRGH) has not been assessed in Latin American immigrant and native workers across host countries. Cross-sectional study of the association between long work hours (LWH) (i.e., >51 hr per week) and poor SRGH using data from 2,626 workers in the United States (immigrants = 10.4%) and 8,306 workers in Spain (immigrants = 4.1%). Both countries' natives working >51 hr per week had increased odds of reporting poor SRGH compared to those working fewer hours (U.S.: OR = 1.59; 95%CI = 1.01-2.49; Spain: OR = 2.17; 95%CI = 1.71-2.75); when stratified by sex, increased odds also were observed among immigrant female workers in Spain (OR = 3.47; 95%CI = 1.15-10.5). LWH were associated with differential health outcomes in populations of native and Latin American immigrant workers in the United States and Spain, which may reflect social or occupational inequalities in general or resulting from the 2008 financial crisis. Am. J. Ind. Med. 59:1105-1111, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  4. Geochemical monitoring of volcanic lakes. A generalized box model for active crater lakes

    Directory of Open Access Journals (Sweden)

    Franco Tassi

    2011-06-01

    Full Text Available

    In the past, variations in the chemical contents (SO42−, Cl−, cations of crater lake water have not systematically demonstrated any relationships with eruptive activity. Intensive parameters (i.e., concentrations, temperature, pH, salinity should be converted into extensive parameters (i.e., fluxes, changes with time of mass and solutes, taking into account all the internal and external chemical–physical factors that affect the crater lake system. This study presents a generalized box model approach that can be useful for geochemical monitoring of active crater lakes, as highly dynamic natural systems. The mass budget of a lake is based on observations of physical variations over a certain period of time: lake volume (level, surface area, lake water temperature, meteorological precipitation, air humidity, wind velocity, input of spring water, and overflow of the lake. This first approach leads to quantification of the input and output fluxes that contribute to the actual crater lake volume. Estimating the input flux of the "volcanic" fluid (Qf- kg/s –– an unmeasurable subsurface parameter –– and tracing its variations with time is the major focus during crater lake monitoring. Through expanding the mass budget into an isotope and chemical budget of the lake, the box model helps to qualitatively characterize the fluids involved. The (calculated Cl− content and dD ratio of the rising "volcanic" fluid defines its origin. With reference to continuous monitoring of crater lakes, the present study provides tips that allow better calculation of Qf in the future. At present, this study offers the most comprehensive and up-to-date literature review on active crater lakes.

  5. Graphical processing unit implementation of an integrated shape-based active contour: Application to digital pathology

    Directory of Open Access Journals (Sweden)

    Sahirzeeshan Ali

    2011-01-01

    Full Text Available Commodity graphics hardware has become a cost-effective parallel platform to solve many general computational problems. In medical imaging and more so in digital pathology, segmentation of multiple structures on high-resolution images, is often a complex and computationally expensive task. Shape-based level set segmentation has recently emerged as a natural solution to segmenting overlapping and occluded objects. However the flexibility of the level set method has traditionally resulted in long computation times and therefore might have limited clinical utility. The processing times even for moderately sized images could run into several hours of computation time. Hence there is a clear need to accelerate these segmentations schemes. In this paper, we present a parallel implementation of a computationally heavy segmentation scheme on a graphical processing unit (GPU. The segmentation scheme incorporates level sets with shape priors to segment multiple overlapping nuclei from very large digital pathology images. We report a speedup of 19× compared to multithreaded C and MATLAB-based implementations of the same scheme, albeit with slight reduction in accuracy. Our GPU-based segmentation scheme was rigorously and quantitatively evaluated for the problem of nuclei segmentation and overlap resolution on digitized histopathology images corresponding to breast and prostate biopsy tissue specimens.

  6. The Development of Learning Activities in Srijanwittaya General Buddhist Scripture School: A Participatory Action Research

    Directory of Open Access Journals (Sweden)

    Phrachakrapol Pongsir

    2017-06-01

    Full Text Available The objectives of this research were to study: 1 the former and present conditions, problem, expectations, possible alternative solutions to solve problems, achieve expectations and the choices made in formulating an action plan for development of learning activity. 2 the results of both expected and unexpected changes from individual, group and organization, also the new knowledge created from learning by doing processes with participatory action research. The 17 participants consist of administrators, teachers, school committee and 5 stakeholders. Such as administrative officer, caretaker, community leader and representative alumni. Research instruments included an observation form, in-depth interview, and document examination. The research finding were as follows: Srijanwittaya general buddhist scripture school lack of equipment for teaching and learning and modern teaching aids. Teachers have not been development for 21st century learning skills. These were the cause of: bored lesson, low student achievement and school has not passed the third quality evaluation by the office for National Education Standards and Quality Assessment (Public Organization Researcher focus on solving problem by 4 projects were Follows: 1 promotion and development of teacher project 2 developing school environment project. 3 encourage collaboration for school development project and 4 improving manage potential for school based management project. After improving found that Srijanwittaya general buddhist scripture school, Loei province passed the quality evaluation and higher students achievement. Moreover, researcher and participants were learnt from research practice such as knowledge and experience. The new knowledge had 3 characteristics as follows: 1 new knowledge on participatory performance of school context 2 new knowledge by 5 steps of participle learning principal and 3 new knowledge by lesson learned visualizing from “SRIJAN Model”.

  7. Changes in disability in older adults with generalized radiographic osteoarthritis: A complex relationship with physical activity.

    Science.gov (United States)

    Tak, E C P M; van Meurs, J B; Bierma-Zeinstra, S M A; Hofman, A; Hopman-Rock, M

    2017-04-10

    The aim of the present study was to report on factors associated with changes in disability after 5 years, with a focus on physical activity (PA) in community-dwelling older adults with generalized radiographic osteoarthritis (GROA). Assessment of GROA (hand, knee, hip) and disability (Health Assessment Questionnaire) in the Rotterdam Study (cohort RS-1, N = 7,983; with GROA, n = 821). A good outcome at follow-up was defined as improved or mild disability, and a poor outcome as worsened or severe disability. Factors potentially associated with outcome were demographics, joint complaints, other chronic health problems or limitations (body mass index, number of chronic conditions, cognition), and level of different types of PA. Some of these assessments were repeated in between 1997 and 1999 (RS-3), and between 2002 and 2004 (RS-4). A total of 309 older adults with GROA and valid measures on RS-3 and RS-4 showed mild to moderate disability, with minor increases over 5 years (follow-up N = 287 RS-3 to RS-4). PA levels decreased with increasing disability, especially in sport and walking. PA was univariately associated with a better outcome at follow-up but when adjusted for other factors (higher age, having knee pain and stiffness, and having more than two other chronic conditions) was associated with negative changes in general and lower limb disability, although not with upper limb disability. This was the first study to report that community-dwelling older adults with GROA show moderate levels of disability, and that reduced levels of disability are associated with higher levels of PA, but when adjusted for other confounders this association is lost. Further research is needed to study the complex relationships between PA and other determinants of disability. Copyright © 2017 John Wiley & Sons, Ltd.

  8. Predictability of Operant Behavior of Rats by Prefrontal Multiple Unit Activities

    Science.gov (United States)

    Fujiwara, Sei-Etsu; Akema, Tatsuo; Izaki, Yoshinori

    To investigate the possibility of a brain computer interface (BCI) constructed using activities of the prefrontal cortex (PFC), we analyzed PFC multiple unit activities (MUAs) during a delayed reinforcement (DRF) lever press task in rats. In the DRF task, each trial consisted of two lever press responses (R1, R2): R1 as the trial initiation, R2 as a pre-conditioned response to a stimulus (buzzer) for a reward. Between R1 and the buzzer, rats were required to inhibit the lever press (waiting phase). The trial was evaluated as incorrect if rats pressed the lever during the waiting phase. Results show that the mean firing rate (MFR) was significantly lower around the time of R1 compared with the pre-trial time in correct trials, although no significant changes were found in incorrect trials. From a neuroengineering perspective, the MFR of each single trial was calculated. Most correct trials showed decreasing MFR around the time of R1. The PFC MUA might be useful for BCI.

  9. Multiple unit activity recorded longitudinally in rats from pubescence to old age.

    Science.gov (United States)

    Malmo, H P; Malmo, R B

    1982-01-01

    Longitudinal multiple unit activity (MUA) recordings of excellent quality over time periods as long as 26 months are described. The validity of the method was demonstrated by showing persistence of specific and idiosyncratic MUA responses to controlled sensory stimulation over these long time periods. This longitudinal MUA method was used to study level of localization neuronal activity as a function of aging. In agreement with deoxyglucose data from Sokoloff's laboratory, we found significant age-related declines in inferior and superior colliculi. In addition, our results showed the advantage of a longitudinal method over a cross-sectional one in following progressive changes into old age. The further declines in midbrain MUA level (though not in forebrain level) from middle age to old age that we observed were highly significant. The deoxyglucose method, on the other hand, had failed to show this kind of progression in those midbrain sites, probably because of a survival effect, a common sampling artifact in cross-sectional studies of aging.

  10. Biological treatment of synthetic wastewater containing 2,4 dichlorophenol (DCP) in an activated sludge unit.

    Science.gov (United States)

    Kargi, Fikret; Eker, Serkan; Uygur, Ahmet

    2005-08-01

    Chlorophenol compounds present in many chemical industry wastewaters are resistant to biological degradation because of the toxic effects of such compounds on microorganisms. Synthetic wastewater containing different concentrations of 2,4 dichlorophenol (DCP) was subjected to biological treatment in an activated sludge unit. Effects of feed DCP concentration on COD, DCP, and toxicity removals and on sludge volume index were investigated at a constant sludge age of 10 days and hydraulic residence time (HRT) of 25 h. The Resazurin method based on dehydrogenase activity was used for assessment of toxicity for the feed and effluent wastewater. Percent COD, DCP, and toxicity removals decreased and the effluent COD, DCP, and toxicity levels increased with increasing feed DCP concentrations above 150 mgl(-1) because of inhibitory effects of DCP. Biomass concentration in the aeration tank decreased and the sludge volume index (SVI) increased with feed DCP concentrations above 150 mgl(-1) resulting in lower COD and DCP removal rates. The system should be operated at feed DCP concentrations of less than 150 mgl(-1) in order to obtain high COD, DCP, and toxicity removals.

  11. Overview of electromagnetic methods applied in active volcanic areas of western United States

    Science.gov (United States)

    Skokan, Catherine K.

    1993-06-01

    A better understanding of active volcanic areas in the United States through electromagnetic geophysical studies received foundation from the many surveys done for geothermal exploration in the 1970's. Investigations by governmental, industrial, and academic agencies include (but are not limited to) mapping of the Cascades. Long Valley/Mono area, the Jemez volcanic field, Yellowstone Park, and an area in Colorado. For one example — Mt. Konocti in the Mayacamas Mountains, California — gravity, magnetic, and seismic, as well as electromagnetic methods have all been used in an attempt to gain a better understanding of the subsurface structure. In each of these volcanic regions, anomalous zones were mapped. When conductive, these anomalies were interpreted to be correlated with hydrothermal activity and not to represent a magma chamber. Electrical and electromagnetic geophysical methods can offer valuable information in the understanding of volcanoes by being the method which is most sensitive to change in temperature and, therefore, can best map heat budget and hydrological character to aid in prediction of eruptions.

  12. Adquisición de la competencia traductológica: propuesta de una unidad didáctica de traducción general/Acquisition de la compétence traductologique: Proposition d'une unité didactique de la traduction générale/Acquisition of Translatological Competence: Teaching Unit Proposal for General Translation

    National Research Council Canada - National Science Library

    Ahmed Kamal Zaghloul

    2010-01-01

    ...: Didáctica, traducción general, competencia traductológica, enfoque por tareas, traducción de viñetas. Acquisition de la compétence traductologique: Proposition d'une unité didactique de la traduction générale RÉSUMÉ Dans cette étude, nous proposons une unicité didactique à propos de la traduction directe de l'espagnol vers l'arabe...

  13. GENERAL ACTIVITY AND PROTECTIVE BEHAVIOUR OF THE EUROPEAN GROUND SQUIRREL (SPERMOPHILUS CITELLUS IN CAPTIVITY

    Directory of Open Access Journals (Sweden)

    Sandra Franova

    2013-09-01

    Full Text Available We decided to focus our research on two of the basic forms of ground squirrel s behaviour in the semi natural conditions of zoological gardens general activity and protective behavior. Our main goal was to perform a complex analysis of the ground squirrel s behaviour living in captivity and to compare the various categories of behaviour on a set timeline. We performed our research throughout the span of two years 2011 2012, during which we observed two separate ground squirrel colonies A, B. We took our compiled information and subjected these to a thorough statistical analysis and main tools of comparison. Based on a long term observation and analysis of the results, we were able to gather very detailed information about the two categories of the ground squirrel s behavior as well as the various periods on the timeline, which were worked into the ethogram of the ground squirrels living in captivity. The results from 2011 confirmed that the behavior of the ground squirrel bred in captivity both observed categories in the same way as was observed in the wild reaches two peaks with raised frequencies in manifestation of given behavior, mostly in the daily time periods, the first from 9am to 11am and the second from 2.30pm to 5pm. We also noted a change in 2012, when there was a reconstruction nearby the aviaries. These reconstructive activities influenced the behavior significant decrease of activity of the ground squirrels in the presence of the assigned workers approximately until 3pm, from which time also in connection with the lessening of the worker s presence the ground squirrels activity in their aviaries begun to rapidly rise, which held on until 5pm. The peak of protective behavior in 2012 has reached higher levels than the peak in 2011, which we attribute to their vigilance after the previous presence of people. Our results may serve as a basis for improvement of the life conditions of the ground squirrels bred in captivity as well as

  14. Structure–Activity Relationship of Oligomeric Flavan-3-ols: Importance of the Upper-Unit B-ring Hydroxyl Groups in the Dimeric Structure for Strong Activities

    Directory of Open Access Journals (Sweden)

    Yoshitomo Hamada

    2015-10-01

    Full Text Available Proanthocyanidins, which are composed of oligomeric flavan-3-ol units, are contained in various foodstuffs (e.g., fruits, vegetables, and drinks and are strongly biologically active compounds. We investigated which element of the proanthocyanidin structure is primarily responsible for this functionality. In this study, we elucidate the importance of the upper-unit of 4–8 condensed dimeric flavan-3-ols for antimicrobial activity against Saccharomyces cerevisiae (S. cerevisiae and cervical epithelioid carcinoma cell line HeLa S3 proliferation inhibitory activity. To clarify the important constituent unit of proanthocyanidin, we synthesized four dimeric compounds, (−-epigallocatechin-[4,8]-(+-catechin, (−-epigallocatechin-[4,8]-(−-epigallocatechin, (−-epigallocatechin-[4,8]-(−-epigallocatechin-3-O-gallate, and (+-catechin-[4,8]-(−-epigallocatechin and performed structure–activity relationship (SAR studies. In addition to antimicrobial activity against S. cerevisiae and proliferation inhibitory activity on HeLa S3 cells, the correlation of 2,2-diphenyl-l-picrylhydrazyl radical scavenging activity with the number of phenolic hydroxyl groups was low. On the basis of the results of our SAR studies, we concluded that B-ring hydroxyl groups of the upper-unit of the dimer are crucially important for strong and effective activity.

  15. Mapping brain activity on the verge of a photically induced generalized tonic-clonic seizure

    DEFF Research Database (Denmark)

    Moeller, Friederike; Siebner, Hartwig R; Wolff, Stephan

    2009-01-01

    In a photosensitive patient intermittent photic stimulation (IPS) accidentally provoked a generalized tonic-clonic seizure during simultaneous recordings of electroencephalography (EEG) and functional magnetic resonance imaging (fMRI). Before seizure onset, IPS consistently induced generalized ph...

  16. Cost of reactive nitrogen release from human activities to the environment in the United States

    Science.gov (United States)

    Sobota, Daniel J.; Compton, Jana E.; McCrackin, Michelle L.; Singh, Shweta

    2015-02-01

    Leakage of reactive nitrogen (N) from human activities to the environment can cause human health and ecological problems. Often these harmful effects are not reflected in the costs of food, fuel, and fiber that derive from N use. Spatial analyses of damage costs attributable to source at management-relevant scales could inform decisions in areas where anthropogenic N leakage causes harm. We used recently compiled data describing N inputs in the conterminous United States (US) to assess potential damage costs associated with anthropogenic N. We estimated fates of N leaked to the environment (air/deposition, surface freshwater, groundwater, and coastal zones) in the early 2000s by multiplying watershed-level N inputs (8-digit US Geologic Survey Hydrologic Unit Codes; HUC8s) with published coefficients describing nutrient uptake efficiency, leaching losses, and gaseous emissions. We scaled these N leakage estimates with mitigation, remediation, direct damage, and substitution costs associated with human health, agriculture, ecosystems, and climate (per kg of N) to calculate annual damage cost (US dollars in 2008 or as reported) of anthropogenic N per HUC8. Estimates of N leakage by HUC8 ranged from effects of atmospheric N pollution were important across HUC8s. However, significant data gaps remain in our ability to fully assess N damages, such as damage costs from harmful algal blooms and drinking water contamination. Nationally, potential health and environmental damages of anthropogenic N in the early 2000s totaled 210 billion yr-1 USD (range: 81-441 billion yr-1). While a number of gaps and uncertainties remain in these estimates, overall this work represents a starting point to inform decisions and engage stakeholders on the costs of N pollution.

  17. Study of active noise control system for a commercial HVAC unit

    Science.gov (United States)

    Devineni, Naga

    Acoustic noise is a common problem in everyday life. If the appliances that are present in the work and living areas generate noise then it's a serious problem. One such appliance is the Heating, Ventilation and Air-conditioning system (HVAC) in which blower fan and compressor units are housed together. Operation of a HVAC system creates two kinds of noise. One is the noise due to the air flow and the other is the result of the compressor. Both of them exhibit different signal properties and need different strategies to control them. There has been previous efforts in designing noise control systems that can control noise from the HVAC system. These include passive methods which use sound absorption materials to attenuate noise and active methods which cancel noise by generating anti-noise. Passive methods are effective in limiting the high frequency noise, but are inefficient in controlling low frequency noise from the compressor. Compressor noise is one of the strong low frequency components that propagate through the walls, therefore there is need for deploying active signal processing methods that consider the signal properties into consideration to cancel the noise acoustically. The quasi periodic nature of the compressor noise is exploited in noise modeling which aids in implementing an adaptive linear prediction filter in estimating the anti noise [12]. In this thesis, a multi channel architecture has been studied for a specific HVAC system in order to improve noise cancellation by creating larger quiet zone. In addition to the multi-channel architecture, a real time narrow band Active Noise Control (ANC) was employed to cancel noise under practical conditions.

  18. Development of the Self-Powered Extravehicular Mobility Unit Extravehicular Activity Data Recorder

    Science.gov (United States)

    Bernard, Craig; Hill, Terry R.; Murray, Sean; Wichowski, Robert; Rosenbush, David

    2012-01-01

    The Self-Powered Extravehicular Mobility Unit (EMU) Extravehicular Activity (EVA) Data Recorder (SPEEDR) is a field-programmable gate array (FPGA)-based device designed to collect high-rate EMU Primary Life Support Subsystem (PLSS) data for download at a later time. During EVA, the existing EMU PLSS data downlink capability is one data packet every 2 minutes and is subject to bad packets or loss of signal. Higher-rate PLSS data is generated by the Enhanced Caution and Warning System but is not normally captured or distributed. Access to higher-rate data will increase the capability of EMU anomaly resolution team to pinpoint issues remotely, saving crew time by reducing required call-down Q&A and on-orbit diagnostic activities. With no Space Shuttle flights post Fiscal Year 2011 (FY11), and potentially limited down-mass capability, the ISS crew and ground support personnel will have to be capable of on-orbit operations to maintain, diagnose, repair, and return to service EMU hardware, possibly through 2028. Collecting high-rate EMU PLSS data during both intravehicular activity (IVA) and EVA operations will provide trending analysis for life extension and/or predictive performance. The SPEEDR concept has generated interest as a tool/technology that could be used for other International Space Station subsystems or future exploration-class space suits where hardware reliability/availability is critical and low/variable bandwidth may require store then forward methodology. Preliminary work in FY11 produced a functional prototype consisting of an FPGA evaluation board, custom memory/interface circuit board, and custom software. The SPEEDR concept includes a stand-alone battery that is recharged by a computer Universal Serial Bus (USB) port while data are being downloaded.

  19. Evaluation of a Medical and Mental Health Unit compared with standard care for older people whose emergency admission to an acute general hospital is complicated by concurrent 'confusion': a controlled clinical trial. Acronym: TEAM: Trial of an Elderly Acute care Medical and mental health unit.

    Science.gov (United States)

    Harwood, Rowan H; Goldberg, Sarah E; Whittamore, Kathy H; Russell, Catherine; Gladman, John Rf; Jones, Rob G; Porock, Davina; Lewis, Sarah A; Bradshaw, Lucy E; Elliot, Rachel A

    2011-05-13

    Patients with delirium and dementia admitted to general hospitals have poor outcomes, and their carers report poor experiences. We developed an acute geriatric medical ward into a specialist Medical and Mental Health Unit over an eighteen month period. Additional specialist mental health staff were employed, other staff were trained in the 'person-centred' dementia care approach, a programme of meaningful activity was devised, the environment adapted to the needs of people with cognitive impairment, and attention given to communication with family carers. We hypothesise that patients managed on this ward will have better outcomes than those receiving standard care, and that such care will be cost-effective. We will perform a controlled clinical trial comparing in-patient management on a specialist Medical and Mental Health Unit with standard care. Study participants are patients over the age of 65, admitted as an emergency to a single general hospital, and identified on the Acute Medical Admissions Unit as being 'confused'. Sample size is 300 per group. The evaluation design has been adapted to accommodate pressures on bed management and patient flows. If beds are available on the specialist Unit, the clinical service allocates patients at random between the Unit and standard care on general or geriatric medical wards. Once admitted, randomised patients and their carers are invited to take part in a follow up study, and baseline data are collected. Quality of care and patient experience are assessed in a non-participant observer study. Outcomes are ascertained at a follow up home visit 90 days after randomisation, by a researcher blind to allocation. The primary outcome is days spent at home (for those admitted from home), or days spent in the same care home (if admitted from a care home). Secondary outcomes include mortality, institutionalisation, resource use, and scaled outcome measures, including quality of life, cognitive function, disability, behavioural and

  20. Evaluation of a Medical and Mental Health Unit compared with standard care for older people whose emergency admission to an acute general hospital is complicated by concurrent 'confusion': a controlled clinical trial. Acronym: TEAM: Trial of an Elderly Acute care Medical and mental health unit

    Directory of Open Access Journals (Sweden)

    Gladman John RF

    2011-05-01

    Full Text Available Abstract Background Patients with delirium and dementia admitted to general hospitals have poor outcomes, and their carers report poor experiences. We developed an acute geriatric medical ward into a specialist Medical and Mental Health Unit over an eighteen month period. Additional specialist mental health staff were employed, other staff were trained in the 'person-centred' dementia care approach, a programme of meaningful activity was devised, the environment adapted to the needs of people with cognitive impairment, and attention given to communication with family carers. We hypothesise that patients managed on this ward will have better outcomes than those receiving standard care, and that such care will be cost-effective. Methods/design We will perform a controlled clinical trial comparing in-patient management on a specialist Medical and Mental Health Unit with standard care. Study participants are patients over the age of 65, admitted as an emergency to a single general hospital, and identified on the Acute Medical Admissions Unit as being 'confused'. Sample size is 300 per group. The evaluation design has been adapted to accommodate pressures on bed management and patient flows. If beds are available on the specialist Unit, the clinical service allocates patients at random between the Unit and standard care on general or geriatric medical wards. Once admitted, randomised patients and their carers are invited to take part in a follow up study, and baseline data are collected. Quality of care and patient experience are assessed in a non-participant observer study. Outcomes are ascertained at a follow up home visit 90 days after randomisation, by a researcher blind to allocation. The primary outcome is days spent at home (for those admitted from home, or days spent in the same care home (if admitted from a care home. Secondary outcomes include mortality, institutionalisation, resource use, and scaled outcome measures, including quality of

  1. Motor unit firing intervals and other parameters of electrical activity in normal and pathological muscle

    DEFF Research Database (Denmark)

    Fuglsang-Frederiksen, Anders; Smith, T; Høgenhaven, H

    1987-01-01

    analysis and the analysis of properties of individual motor unit potentials. To ensure comparable conditions we have examined motor unit firing intervals and turns at a force of 10% of maximum. The average of motor unit firing intervals and of interval variability was the same in controls and in patients......, and the diagnostic yield of the motor unit firing intervals analysis was none. Although the number of turns increased with decreasing motor unit firing intervals, this relation was physiological rather than pathophysiological. In patients with neurogenic disorders, interval variability indicated unstable firing...

  2. Physical activity and onset of depression in adolescents : A prospective study in the general population cohort TRAILS

    NARCIS (Netherlands)

    Stavrakakis, N.; Roest, A. M.; Verhulst, F.; Ormel, J.; de Jonge, P.; Oldehinkel, A. J.

    2013-01-01

    Although it has often been suggested that physical activity and depression are intertwined, only few studies have investigated whether specific aspects of physical activity predict the incidence of major depression in adolescents from the general population. Therefore the aim of this study was to in

  3. 2 October 2013 - Israel Ambassador to the United Nations Office and other International Organizations at Geneva E. Manor on the occasion of the inauguration of the "Israel at CERN" Industrial Exhibition with CERN Director-General R. Heuer.

    CERN Multimedia

    Anna Pantelia

    2013-01-01

    2 October 2013 - Israel Ambassador to the United Nations Office and other International Organizations at Geneva E. Manor on the occasion of the inauguration of the "Israel at CERN" Industrial Exhibition with CERN Director-General R. Heuer.

  4. Identifying Chronic Conditions and Other Selected Factors That Motivate Physical Activity in World Senior Games Participants and the General Population

    Directory of Open Access Journals (Sweden)

    Ray M. Merrill PhD, MPH

    2015-07-01

    Full Text Available This study assesses chronic disease or disease-related conditions as motivators of physical activity. It also compares these and other motivators of physical activity between Senior Games participants (SGPs and the general population. Analyses are based on an anonymous cross-sectional survey conducted among 666 SGPs and 177 individuals from the general population. SGPs experienced better general health and less obesity, diabetes, and depression, as well as an average of 14.7 more years of regular physical activity (p < .0001, 130.8 more minutes per week of aerobic activity (p < .0001, and 42.7 more minutes of anaerobic activity per week (p < .0001. Among those previously told they had diabetes, high blood pressure, high cholesterol, or depression, 74.2%, 72.2%, 70.4%, and 60.6%, respectively, said that it motivated them to increase their physical activity. Percentages were similar between SGPs and the general population. SGPs were more likely motivated to be physically active to improve physical and mental health in the present, to prevent physical and cognitive decline in the future, and to increase social opportunities. The Senior Games reinforces extrinsic motivators to positively influence intrinsic promoters such as skill development, satisfaction of learning, enjoyment, and fun.

  5. Software & Hardware Architecture of General-Purpose Graphics Processing Unit%GPU通用计算软硬件处理架构研究

    Institute of Scientific and Technical Information of China (English)

    谢建春

    2013-01-01

    现代GPU不仅是功能强劲的图形处理引擎,也是具有强大计算性能和存储带宽的高度并行可编程器件,能够与CPU构建完整的异构处理系统.而将GPU用于图形处理以外的计算,一般称之为GPU通用计算(General-Purpose computing on Graphics Processing Unit,GPGPU).对GPU通用计算的概念及分类、硬件架构及工作机制、软件环境及处理模型进行详细的研究,期望为GPU通用计算在航空嵌入式计算领域的进一步应用提供参考.

  6. Chronic neural probe for simultaneous recording of single-unit, multi-unit, and local field potential activity from multiple brain sites

    Science.gov (United States)

    Pothof, F.; Bonini, L.; Lanzilotto, M.; Livi, A.; Fogassi, L.; Orban, G. A.; Paul, O.; Ruther, P.

    2016-08-01

    Objective. Drug resistant focal epilepsy can be treated by resecting the epileptic focus requiring a precise focus localisation using stereoelectroencephalography (SEEG) probes. As commercial SEEG probes offer only a limited spatial resolution, probes of higher channel count and design freedom enabling the incorporation of macro and microelectrodes would help increasing spatial resolution and thus open new perspectives for investigating mechanisms underlying focal epilepsy and its treatment. This work describes a new fabrication process for SEEG probes with materials and dimensions similar to clinical probes enabling recording single neuron activity at high spatial resolution. Approach. Polyimide is used as a biocompatible flexible substrate into which platinum electrodes and leads are integrated with a minimal feature size of 5 μm. The polyimide foils are rolled into the cylindrical probe shape at a diameter of 0.8 mm. The resulting probe features match those of clinically approved devices. Tests in saline solution confirmed the probe stability and functionality. Probes were implanted into the brain of one monkey (Macaca mulatta), trained to perform different motor tasks. Suitable configurations including up to 128 electrode sites allow the recording of task-related neuronal signals. Main results. Probes with 32 and 64 electrode sites were implanted in the posterior parietal cortex. Local field potentials and multi-unit activity were recorded as early as one hour after implantation. Stable single-unit activity was achieved for up to 26 days after implantation of a 64-channel probe. All recorded signals showed modulation during task execution. Significance. With the novel probes it is possible to record stable biologically relevant data over a time span exceeding the usual time needed for epileptic focus localisation in human patients. This is the first time that single units are recorded along cylindrical polyimide probes chronically implanted 22 mm deep into the

  7. A tailored relocation stress intervention programme for family caregivers of patients transferred from a surgical intensive care unit to a general ward.

    Science.gov (United States)

    Lee, Seul; Oh, HyunSoo; Suh, YeonOk; Seo, WhaSook

    2017-03-01

    To develop and examine a relocation stress intervention programme tailored for the family caregivers of patients scheduled for transfer from a surgical intensive care unit to a general ward. Family relocation stress syndrome has been reported to be similar to that exhibited by patients, and investigators have emphasised that nurses should make special efforts to relieve family relocation stress to maximise positive contributions to the well-being of patients by family caregivers. A nonequivalent control group, nonsynchronised pretest-post-test design was adopted. The study subjects were 60 family caregivers of patients with neurosurgical or general surgical conditions in the surgical intensive care unit of a university hospital located in Incheon, South Korea. Relocation stress and family burden were evaluated at three times, that is before intervention, immediately after transfer and four to five days after transfer. This relocation stress intervention programme was developed for the family caregivers based on disease characteristics and relocation-related needs. In the experimental group, relocation stress levels significantly and continuously decreased after intervention, whereas in the control group, a slight nonsignificant trend was observed. Family burden levels in the control group increased significantly after transfer, whereas burden levels in the experimental group increased only marginally and nonsignificantly. No significant between-group differences in relocation stress or family burden levels were observed after intervention. Relocation stress levels of family caregivers were significantly decreased after intervention in the experimental group, which indicates that the devised family relocation stress intervention programme effectively alleviated family relocation stress. The devised intervention programme, which was tailored to disease characteristics and relocation-related needs, may enhance the practicality and efficacy of relocation stress

  8. Generalized product

    OpenAIRE

    Greco,Salvatore; Mesiar, Radko; Rindone, Fabio

    2014-01-01

    Aggregation functions on [0,1] with annihilator 0 can be seen as a generalized product on [0,1]. We study the generalized product on the bipolar scale [–1,1], stressing the axiomatic point of view. Based on newly introduced bipolar properties, such as the bipolar increasingness, bipolar unit element, bipolar idempotent element, several kinds of generalized bipolar product are introduced and studied. A special stress is put on bipolar semicopulas, bipolar quasi-copulas and bipolar copulas.

  9. Generalized product

    OpenAIRE

    Greco, Salvatore; Mesiar, Radko; Rindone, Fabio

    2014-01-01

    Aggregation functions on [0,1] with annihilator 0 can be seen as a generalized product on [0,1]. We study the generalized product on the bipolar scale [–1,1], stressing the axiomatic point of view. Based on newly introduced bipolar properties, such as the bipolar increasingness, bipolar unit element, bipolar idempotent element, several kinds of generalized bipolar product are introduced and studied. A special stress is put on bipolar semicopulas, bipolar quasi-copulas and bipolar copulas.

  10. [The activity of local health units in agriculture: promotion, prevention, control].

    Science.gov (United States)

    Angotzi, G; Ariano, E; Quercia, A

    2010-01-01

    Agriculture shows an high proportion of injuries, mostly by machineries and instruments, and the highest proportion between fatal and total injuries. The Conference of Regions has adopted the National Agriculture and Forestry Prevention Plan, in application of the "Pact for health and safety in workplaces". The plan gives priority to actions improving the safety of agricultural machines, specially if more frequently involved in serious and fatal injuries. Goal is to achieve an homogenous intervention standard all over in the country, composed by a mix of information, support and control, addressed to farms and agricultural machines traders. Public prevention organizations of Local Health Units moreover will record homogenously the happen modality of fatal and serious accidents, will collaborate in joining prevention objectives with Rural Develop Plans and in drawing up good practices. At another level in some regions have been developed prevention activities for other risk factors: definition of exposition profiles of pesticides, development of professionally exposed workers formation, control of buildings and cattle breeding, medical and epidemiological periodic survey of employees.

  11. Mathematical modeling of copper(II) ion inhibition on COD removal in an activated sludge unit.

    Science.gov (United States)

    Pamukoglu, M Yunus; Kargi, Fikret

    2007-07-19

    A mathematical model was developed to describe the Cu(II) ion inhibition on chemical oxygen demand (COD) removal from synthetic wastewater containing 15 mg l(-1) Cu(II) in an activated sludge unit. Experimental data obtained at different sludge ages (5-30 days) and hydraulic residence times (HRT) (5-25 h) were used to determine the kinetic, stoichiometric and inhibition constants for the COD removal rate in the presence and absence of Cu(II) ions. The inhibition pattern was identified as non-competitive, since Cu(II) ion inhibitions were observed both on maximum specific substrate removal rate (k) and on the saturation constant (Ks) with the inhibition constants of 97 and 18 mg l(-1), respectively, indicating more pronounced inhibition on Ks. The growth yield coefficient (Y) decreased and the death rate constant (b) increased in the presence of Cu(II) ions due to copper ion toxicity on microbial growth with inhibition constants of 29 and 200 mg l(-1), respectively indicating more effective inhibition on the growth yield coefficient or higher maintenance requirements. The mathematical model with the predetermined kinetic constants was able to predict the system performance reasonably well especially at high HRT operations.

  12. Arbitrary units are a composite and useful measure of muscle sympathetic nerve activity.

    Science.gov (United States)

    Thakre, Tushar P; Kulkarni, Hemant; Mamtani, Manju R; Smith, Michael

    2009-08-01

    In humans, the muscle sympathetic nerve activity (MSNA) signal is challenging to detect, record and analyze. Several methods exist that attempt to capture the latent construct of MSNA. We directly compared the performance of five MSNA parameters: burst frequency, burst incidence, median burst amplitude, arbitrary units (AU) and fractal dimension (FD). The MSNA signal was recorded in 33 subjects for approximately 30 min before, during and after the application of a graded cold pressor test stimulus at 18 degrees C, 10 degrees C and 2 degrees C in random order with an adequate wash-out period. Using coefficient of variation, Shannon's entropy and principal component analysis, we observed that these five parameters defined two physical and conceptual domains of MSNA-frequency and amplitude. Since AU combines information from both these domains, we observed that it explained maximum inter-subject and inter-experimental segment variation. FD did not explain the inter-subject variability and was identified as a unique parameter in the factor analysis. Epidemiological studies that attempt to quantify MSNA may consistently use AU as the parameter for quantification of MSNA.

  13. Electromagnetic radiation from VDT units: study of the effectiveness of an active shielding device.

    Science.gov (United States)

    Sisto, R; Casciardi, S; Giliberti, C; Moleti, A

    1999-01-01

    Measurements of extremely low frequency electromagnetic fields and low frequency magnetic fields emitted by a set of video display terminal (VDT) units are reported. The field values measured at the position normally occupied by the user are below the safety limits. This is because the field amplitudes decrease rapidly (following a 1/R3 law) with the distance from the source, as has been verified in this work. Measurements with a commercial shielding device consisting of small plastic balls filled with a water solution of rare earth elements were also performed. The only physical mechanism that could be hypothesized to produce an active suppression of the VDT field is that rare earth atoms, which probably were chosen due to their large magnetic moment, behave as oscillating magnetic dipoles capable of emitting a secondary magnetic field that, along some particular directions, has a phase that is opposite to that of the exciting field. Unfortunately, if one analyzes this mechanism quantitatively, it is easy to show that the secondary magnetic field is absolutely negligible, as was confirmed by experimental measurements performed in this study.

  14. Nursing Activities Score: an updated guideline for its application in the Intensive Care Unit

    Directory of Open Access Journals (Sweden)

    Katia Grillo Padilha

    2015-12-01

    Full Text Available ABSTRACT Objective To describe nursing workload in Intensive Care Units (ICU in different countries according to the scores obtained with Nursing Activities Score (NAS and to verify the agreement among countries on the NAS guideline interpretation. Method This cross-sectional study considered 1-day measure of NAS (November 2012 obtained from 758 patients in 19 ICUs of seven countries (Norway, the Netherlands, Spain, Poland, Egypt, Greece and Brazil. The Delphi technique was used in expertise meetings and consensus. Results The NAS score was 72.8% in average, ranging from 44.5% (Spain to 101.8% (Norway. The mean NAS score from Poland, Greece and Egypt was 83.0%, 64.6% and 57.1%, respectively. The NAS score was similar in Brazil (54.0% and in the Netherlands (51.0%. There were doubts in the understanding of five out 23 items of the NAS (21.7% which were discussed until researchers’ consensus. Conclusion NAS score were different in the seven countries. Future studies must verify if the fine standardization of the guideline can have a impact on differences in the NAS results.

  15. A randomised controlled trial to improve general practitioners' services in cancer rehabilitation: Effects on general practitioners' proactivity and on patients' participation in rehabilitation activities

    DEFF Research Database (Denmark)

    Bergholdt, SH; Søndergaard, J; Larsen, PV

    2013-01-01

    Abstract Few studies have evaluated initiatives targeting implementation of cancer rehabilitation. In this study we aim to test the effects of a complex intervention designed to improve general practitioners' (GPs) involvement in cancer rehabilitation. Outcomes were proactive contacts to patients...... to an intervention and 469 to a control group. The intervention included a patient interview about rehabilitation with a rehabilitation coordinator at the hospital, comprehensive information to the GP about individual needs for rehabilitation, and an encouragement to the GP to contact the patient proactively......- or GP-reported extent of GP proactivity. Further, no effect was observed on patient participation in rehabilitation activities during the 14-month follow-up period. Discussion. The intervention had no effect on GP proactivity or on patient participation in rehabilitation activities. However, analyses...

  16. Viabilidade de unidades psiquiátricas em hospitais gerais no Brasil Viabilidad de unidades psiquiátricas en hospitales generales en Brasil Feasibility of general hospitals psychiatric units in Brazil

    Directory of Open Access Journals (Sweden)

    Maurício Lucchesi

    2009-02-01

    Taubate (Sureste de Brasil, 2005-2006. Las evidencias fueron obtenidas por medio de entrevistas, observación participante y palestras sobre el proyecto de la unidad psiquiátrica para el cuerpo clínico del hospital. RESULTADOS: La inversión del órgano gestor posibilitó que las concepciones estigmatizantes presentes en la cultura del hospital estudiado (violencia, debilidad moral e intratabilidad fueran resignificadas por medio de discusiones clínicas y sanitarias, viabilizando la implantación de la unidad psiquiátrica. El análisis mostró que esas concepciones eran reactualizadas por el contexto asistencial, en el cual el acceso de los portadores de trastornos mentales era restringido. CONCLUSIONES: La postura asumida por el órgano gestor, que decidió por el financiamiento adecuado de la unidad psiquiátrica y ejerció su ascendencia sobre el hospital prestador, fue decisiva para el desenlace del caso. La principal dificultad para la implantación de las unidades psiquiátricas no es el estigma presente en la cultura de los hospitales generales, pero una limitación de orden estratégica: la falta de una política afirmativa para esas unidades.OBJECTIVE: To comprehend the stigma against people with mental disorders still persists in the culture of general hospitals and acts as a limiting factor in the implementation of psychiatric units in general hospitals in Brazil. METHODOLOGICAL PROCEDURES: A qualitative social survey was outlined based on action research strategy as of the agreement to adopt a psychiatric unit in a general hospital in Taubaté, Southeastern Brazil. Data was obtained through interviews, participant observation and talks on the psychiatric unit project given to the hospital's clinical staff. RESULTS: The investment made by the healthcare authority enabled the stigmatizing conceptions (violence, moral weakness and untreatability present in the hospital culture in question to be resignified by means of clinical and sanitary discussions, which

  17. Targeting physical activity promotion in general practice: Characteristics of inactive patients and willingness to change

    Directory of Open Access Journals (Sweden)

    Sánchez-Pinilla Ricardo

    2008-05-01

    Full Text Available Abstract Background Counselling in routine general practice to promote physical activity (PA is advocated, but inadequate evidence is available to support this intervention, and its sustainable implementation over time is difficult. Objectives To describe the characteristics of physically inactive adults visiting GPs and the factors associated with their willingness to change PA. Methods A cross-sectional analysis of 4317 Spanish people aged 20–80 years, selected by systematic sampling among those attending 56 public primary health care practices identified as inactive by their GPs in 2003. PA (7-day PAR, PA stage of change, health-related quality of life (SF-36, cardiovascular risk factors, and social and demographic characteristics were measured. Multivariate mixed effects ordinal logistic models were adjusted to identify factors associated with motivational readiness to change. Results At least 70% (95% CI: 67.6% to 72.8% of patients assessed by GPs did not achieve minimal PA recommendations. In addition, 85% (95% CI: 83% to 86.3% had at least an additional cardiovascular risk factor. Only 30% (95% CI: 25.8% to 33.5% were prepared for or attempting a change. A younger age; retirement or work at home; higher education and social class levels; obesity; and hypertension were associated with a higher motivational readiness to change (p Conclusion The overburden that would result from counselling such a high proportion of inactive primary care patients justifies a targeted strategy for PA promotion in family practice. Selection of a target population based on readiness to change, the combination of risk factors and socio-demographic characteristics of patients is suggested in order to prioritise promotion efforts.

  18. Full-cost determination of different levels of care in the intensive care unit. An activity-based costing approach.

    Science.gov (United States)

    Doyle, J J; Casciano, J P; Arikian, S R; Mauskopf, J; Paul, J E

    1996-10-01

    We applied an activity-based costing methodology to determine the full cost of intensive care service at a community hospital, a university hospital and a health maintenance organisation (HMO)-affiliated hospital. A total of 5 patient care units were analysed: the intensive care unit (ICU) and surgical ICU (SICU) at the university setting, the ICU at the community setting, and the SICU and cardiac care unit at the HMO setting. The selection of the different ICU types was based on the types of critical care units that were found in each setting (e.g. the HMO did not have an ICU). Institution-specific cost data and clinical management parameters were collected through surveys and site visits from the 3 respective organisation types. The analysis revealed a marked increase in patient-minute cost associated with mechanical ventilation. Higher costs associated with prolonged neuromuscular blockade have important economic implications with respect to selection of an appropriate neuromuscular blocking agent.

  19. Scientific activity of the spanish liberal exiles in the United Kingdom, 1823-1833

    Directory of Open Access Journals (Sweden)

    Valera Candel, Manuel

    2007-06-01

    Full Text Available In 1823, after the squashing of Riego and the restoration of the absolutism of Fernando VII, most of the Spanish liberals went to England, where they carried out different scientific and technical activities. Among the émigrés there was reputed scientists, like Bauzá, Lagasca o Seoane, that in London were able to continue with their scientific activities. Other émigrés carried out an important activity of diffusion of scientific and technical advances through papers and notes that appeared in different magazines of general character published in the Spanish language; of special interest was El Museo Universal de Ciencias y Artes, directed and edited by J. J. Mora, and dedicated entirely to the scientific and technical divulgation. There was, likewise, another activity related to the scientific education, the «scientific catechisms», brief textbooks on mathematics, geography, chemistry, natural sciences, etc., directed towards elementary teaching and aimed to Latino American people, published by Ackermann. In the present work, we offer a comprehensive description of thes  activities.

    En 1823, tras el aplastamiento de Riego y la reinstauración del absolutismo fernandino, se produjo un exilio masivo de liberales hacia el Reino Unido, donde realizaron diversas actividades relacionadas con la ciencia y la técnica. Entre los liberales exiliados había reputados científicos, como Mariano Lagasca, Felipe Bauzá o Mateo Seoane, que en Londres pudieron proseguir con sus actividades científicas. Otros emigrados realizaron una importante labor de difusión de los adelantos científicos y técnicos a través de las diferentes revistas editadas en lengua española; entre ellas
    destacó El Museo Universal de Ciencias y Artes, dirigida y redactada por J. J. de Mora, dedicada íntegramente a la divulgación científico-técnica. Hubo, finalmente, otra actividad relacionada con la educación científica, la elaboración de los

  20. IT and Activity Displacement: Behavioral Evidence from the U.S. General Social Survey (GSS)

    Science.gov (United States)

    Robinson, John P.; Martin, Steven

    2009-01-01

    In order to track social change during a period of the rapid advances brought about by new information technologies (IT), a targeted module of IT-relevant and Internet questions was added to the 2000, 2002 and 2004 samples of the General Social Survey (GSS). The general issue inherent in and guiding the questions asked (as well as the analyses…

  1. Flexibility and Coordination among Acts of Visualization and Analysis in a Pattern Generalization Activity

    Science.gov (United States)

    Nilsson, Per; Juter, Kristina

    2011-01-01

    This study aims at exploring processes of flexibility and coordination among acts of visualization and analysis in students' attempt to reach a general formula for a three-dimensional pattern generalizing task. The investigation draws on a case-study analysis of two 15-year-old girls working together on a task in which they are asked to calculate…

  2. General-base catalysed hydrolysis and nucleophilic substitution of activated amides in aqueous solutions

    NARCIS (Netherlands)

    Buurma, NJ; Blandamer, MJ; Engberts, JBFN; Buurma, Niklaas J.

    2003-01-01

    The reactivity of 1-benzoyl-3-phenyl-1,2,4-triazole (1a) was studied in the presence of a range of weak bases in aqueous solution. A change in mechanism is observed from general-base catalysed hydrolysis to nucleophilic substitution and general-base catalysed nucleophilic substitution. A slight tend

  3. Knee complaints seen in general practice : active sport participants versus non-sport participants

    NARCIS (Netherlands)

    van Middelkoop, Marienke; van Linschoten, Robbart; Berger, Marjolein Y.; Koes, Bart W.; Bierma-Zeinstra, Sita M. A.

    2008-01-01

    Background: Since knee complaints are common among athletes and are frequently presented in general practice, it is of interest to investigate the type of knee complaints represented in general practice of athletes in comparison with those of non-athletes. Therefore, the aim of this study is to inve

  4. Knee complaints seen in general practice : active sport participants versus non-sport participants

    NARCIS (Netherlands)

    van Middelkoop, Marienke; van Linschoten, Robbart; Berger, Marjolein Y.; Koes, Bart W.; Bierma-Zeinstra, Sita M. A.

    2008-01-01

    Background: Since knee complaints are common among athletes and are frequently presented in general practice, it is of interest to investigate the type of knee complaints represented in general practice of athletes in comparison with those of non-athletes. Therefore, the aim of this study is to

  5. A Class of Quasi-Linear Riemann-Hilbert Problems for General Holomorphic Functions in the Unit Disk%一类圆域上广义解析函数拟线性Riemann-Hilbert问题

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    In this paper, a class of quasi-linear Rie mann-Hilbert problems for general holomorphic functions in the unit disk was studied. Under suitable hypotheses, the existence of solutions of the Hardy class H2 to this problem was proved by means of Tikhonov' s fixed point theorem and corresponding theories for general holomorphic functions

  6. [Is the observation of patients with sleep-apnea-syndrome after surgery of the upper airway in an intensive care unit generally necessary?].

    Science.gov (United States)

    Kehrl, W; Schottke-Hennings, H; Offergeld, Ch; Grundmann, T

    2005-04-01

    Although it is known that after surgery of the nose and/or the paranasal sinuses serious complications can arise for patients suffering from Sleep-Apnea-Syndrome (SAS), there exists no general recommendation for postoperative care of these patients. This retrospective analysis is dealing with the question whether it is generally necessary to observe SAS-patients after nasal surgery including intubation in an Intensive Care Unit (ICU). 24 Patients of the ORL-Dept., Marienkrankenhaus Hamburg, suffering from SAS underwent surgery of the nose, the paranasal sinuses and/or the pharynx including total intravenous anesthesia (TIVA) during the period of 1. 10. 2000 until 1. 5. 2004. SAS was diagnosed in 6 cases due to defined clinical criteria and in 18 cases due to the polysomnographic findings in the sleeping laboratory's examination. All patients were observed postoperatively for one night in an ICU. The anesthesia protocol and the intensive care curve of each patient were systematically evaluated with special regard of the following parameters: Risk factors (Body Mass Index; other diseases, ASA-classification), premedication drugs, duration of the surgery, drugs for pain relief, lowest O2-saturation of blood, lowest heartrate, highest systolic blood pressure, adverse effects, intensive care interventions. Intensive care interventions were never needed. 2 patients received a low dosage of oxygeninsufflation via a face mask, in 5 cases calcium-antagonist drugs were administered due to high blood pressure and in 1 case Metamizole administration was necessary due to high temperatures. An accompanying bradycardia of the same patient was treated by administration of Atropine. The lower average O2-saturation was 93.6 +/- 1.7 % (Minimum value: 89 %). The maximum systolic blood pressure was 165.8 +/- 21.2 mm Hg and the lowest average heart rate was 65.4 +/- 13.2 bpm. Patients suffering from a mild to moderate SAS do not need a general postoperative surveillance in an ICU if the

  7. Enhancing Information Usefulness by Line Managers’ Involvement in Cross-Unit Activities

    DEFF Research Database (Denmark)

    Foss, Kirsten; Rodgers, Waymond

    2011-01-01

    of line managers’ prior involvement with Corporate Audit using Throughput Modeling. This model allows us to understand how line managers’ cross-unit involvement influenced the way they process information received from Corporate Audit. Our results show that managers’ cross-unit involvement positively...... influences their assessment of information from Corporate Audit in a way that influences their propensity to use information from that unit. The results indicate that cross-unit involvement is more than an effective means of transmitting information – it can also be used as a means of building boundary......Organization and management scholars have long advocated that efficient use of information is critical for firms to compete successfully in the modern marketplace. This study examines whether the use of managerial cross-unit involvement in an organization enhances managers’ propensity to use useful...

  8. The levels of forming at students of general school operating mobility as executive component of arbitrary management of moving activity.

    Directory of Open Access Journals (Sweden)

    Artyushenko A.A.

    2011-03-01

    Full Text Available The aim of researches is to determine concept «Personality mobility» in the light of pictures of arbitrary management conduct and activity of man In the article is considered question of diagnostics of forming operating mobility for the students of general school as activity of constituent of arbitrary management. It is certain four levels of formed operating mobility for lower boys, for teenagers and for senior pupils. It is well-proven that for period of studies at general school the indexes of operating mobility of students are not change substantially.

  9. UNIT, TIBET.

    Science.gov (United States)

    Louisiana Arts and Science Center, Baton Rouge.

    THE UNIT OF STUDY DESCRIBED IN THIS BOOKLET DEALS WITH THE GEOGRAPHY AND HISTORY OF TIBET. THE UNIT COVERS SOME OF THE GENERAL FEATURES OF THE COUNTRY AND THEIR EFFECT UPON THE LIVES OF THE TIBETAN PEOPLE. DISCUSSION QUESTIONS ARE INSERTED TO STIMULATE THOUGHT. THE RELIGION OF TIBET IS DISCUSSED IN RELATION TO ITS INFLUENCE ON THE ART AND CULTURE…

  10. Self-Efficacy and Participation in Physical and Social Activity among Older Adults in Spain and the United States

    Science.gov (United States)

    Perkins, Jessica M.; Multhaup, Kristi S.; Perkins, H. Wesley; Barton, Cole

    2008-01-01

    Purpose: We explored Bandura's self-efficacy theory as applied to older adult (aged 63-92) participation in physical and social activity in a cross-cultural study. Design and Methods: Older adults in Spain (n = 53) and the United States (n = 55) completed questions regarding self-efficacy, outcome expectancy, and participation in physical and…

  11. Mangroves Build Land. "Mangroves are a Valuable Resource." Grades 7 and 8. A Two Lesson Unit. Student Learning Activity Module.

    Science.gov (United States)

    Frank, James

    This module is an activity and film-oriented unit focusing on the importance of mangroves in the South Florida ecosystem. The module is part of a series designed to be used by teachers, students, and community members to help them utilize community resources in developing and teaching environmental concepts and responsibility, and in seeking ways…

  12. Influence of Negotiations between Preservice Teachers and Pupils on Instruction within Multi-Activity and Sport Education Units

    Science.gov (United States)

    Wahl-Alexander, Zachary; Curtner-Smith, Matthew D.

    2015-01-01

    The purpose of this study was to examine the influence of negotiations between pupils and preservice teachers (PTs) on PTs' instruction within multi-activity (MA) teaching and sport education (SE). Participants were 17 PTs engaged in a secondary early field experience in which they taught 12-lesson MA and SE soccer units. Data were collected using…

  13. Interruptions of activities experienced by nursing professionals in an intensive care unit.

    Science.gov (United States)

    Prates, Daniele de Oliveira; Silva, Ana Elisa Bauer de Camargo

    2016-09-09

    to analyze the interruptions experienced by nursing professionals while undertaking care activities. an observational study undertaken in two intensive care units. Two nurses observed 33 nursing professionals for three hours. The data were recorded in real time, using a semistructured instrument. after 99 hours of observation of 739 activities, it was identified that 46.82% were interrupted, resulting in 7.85 interruptions per hour. On average, the interruptions compromised 9.42% of the nursing professionals' worktime. The activities geared towards indirect care of the patient suffered the highest number of interruptions (56.65%), with the nursing records being the activity interrupted most. The principal source of the interruptions was external, coming from the health professionals (51%), and the main causes were those related to the patients (34.70%) and to interpersonal communication (26.47%). the activity of nursing suffers a high number of interruptions, mainly caused by the health professionals themselves, indicating that the work environment needs to undergo interventions aiming to reduce the risk of compromising of the professional's performance and to increase the patients' safety. analisar as interrupções experienciadas por profissionais de enfermagem durante realização de atividades assistenciais. estudo observacional realizado em duas unidades de tratamento intensivo. Dois enfermeiros observaram 33 profissionais de enfermagem, por três horas. Os dados foram registrados em tempo real, usando um instrumento semiestruturado. após 99 horas de observação de 739 atividades, foi identificado que 46,82% sofreram interrupções, perfazendo 7,85 interrupções por hora. As interrupções comprometeram, em média, 9,42% do tempo de trabalho dos profissionais de enfermagem. As atividades direcionadas ao cuidado indireto do paciente foram as que sofreram maior número de interrupções (56,65%), sendo o registro de enfermagem a atividade mais interrompida. A

  14. Reliability of Wearable Inertial Measurement Units to Measure Physical Activity in Team Handball.

    Science.gov (United States)

    Luteberget, Live S; Holme, Benjamin R; Spencer, Matt

    2017-09-05

    The purpose of this study was to assess the reliability and sensitivity of commercially available inertial measurement units (IMU) to measure physical activity in team handball. Twenty-two handball players were instrumented with two IMUs (OptimEye S5, Catapult Sports, Australia) taped together. They participated in either a laboratory assessment (n=10), consisting of seven team handball specific tasks, or field assessment (n=12) conducted in twelve training sessions. Variables, including PlayerLoad™ and inertial movement analysis (IMA) magnitude and counts, were extracted from the manufactures software. IMA count was divided into intensity bands of low (1.5-2.5m·s(-1)), medium (2.5-3.5m·s(-1)), high (>3.5m·s(-1)), medium/high (>2.5m·s(-1)), and total (>1.5m·s(-1)). Reliability between devices and sensitivity was established using coefficient of variation (CV) and smallest worthwhile difference (SWD). Laboratory assessment : IMA magnitude showed a good reliability (CV: 3.1%) in well-controlled tasks. CV increased (4.4-6.7%) in more complex tasks. Field assessment : Total IMA count (CV: 1.8%, SWD: 2.5%), PlayerLoad™ (CV: 0.9 % SWD: 2.1%), and its associated variables (CV: 0.4-1.7%) showed a good reliability, well below the SWD. However, the CV of IMA increased when categorized into intensity bands (2.9-5.6%). The reliability of IMA count were good, when data was displayed as total, high or medium/high counts. A good reliability for PlayerLoad™ and associated variables was evident. The CV of the aforementioned variables was well below the SWD, suggesting that OptimEye IMU and its software are sensitive for use in team handball.

  15. Take-Home Challenges: Extending Discovery-Based Activities beyond the General Chemistry Classroom

    Science.gov (United States)

    Mason, P. K.; Sarquis, A. M.

    1996-04-01

    In an effort to more effectively integrate the experimental nature of chemistry into our students' experiences, we are developing and implementing discovery-based activities into both the laboratory and lecture components of general chemistry. Below we describe and provide an example of a "take-home challenge" intended to supplement the lecture component of the course. These take-home challenges involve the student in chemistry exploration outside of class and extend the context of content and experimentation into a nontraditional laboratory environment. Over 25 take-home challenges have been developed to date. Preliminary evaluation of the impact of the take-home challenges shows that students reporting themselves as receiving a B or C grade in the course find the challenges very useful in helping them gain a conceptual understanding of the phenomena addressed. Students earning an A grade report little or no impact on their learning. Prepared as one-page handouts, each take-home challenge begins with a scene-setting introduction followed by pertinent background information, a list of materials to be collected, and any appropriate safety precautions. The exploration component of the activity integrates leading questions with the procedural instructions to help guide the students through the discovery process and challenge them to stretch their understanding of the chemistry. After completing a take-home challenge activity, students submit written reports containing responses to the questions posed, observations of data collected, and their responses to the challenge. The accompanying sample take-home challenge activity is provided as a novel adaptation of the belch phenomenon that challenges students to experiment in order to explain the factors that account for the observed behavior. Persons interested in field testing the take-home challenges with their classes should contact the authors. Belch Bottle Challenge: What factors are responsible for the behavior of a

  16. An Analysis of the Romanian General Accounting Plan. Opportunities for Adaptation to the Activity-Based Costing (ABC Method

    Directory of Open Access Journals (Sweden)

    Irina-Alina Preda

    2008-11-01

    Full Text Available In this article, we analyze the causes that have led to the improvement of the Romanian general accounting plan according to the Activity- Based Costing (ABC method. We explain the advantages presented by the dissociated organization of management accounting, in contrast with the tabular- statistical form. The article also describes the methodological steps to be taken in the process of recording book entries, according to the Activity-Based Costing (ABC method in Romania.

  17. General Education Earth, Astronomy and Space Science College Courses Serve as a Vehicle for Improving Science Literacy in the United States.

    Science.gov (United States)

    Prather, E.

    2011-10-01

    Every year approximately 500,000 undergraduate college students take a general education Earth, Astronomy and Space Science (EASS) course in the Unites States. For the majority of these students this will be their last physical science course in life. This population of students is incredibly important to the science literacy of the United States citizenry and to the success of the STEM career pipeline. These students represent future scientists, technologists, business leaders, politicians, journalists, historians, artists, and most importantly, policy makers, parents, voters, and teachers. A significant portion of these students are taught at minority serving institutions and community colleges and often are from underserved and underrepresented groups, such as women and minorities. Members of the Center for Astronomy Education (CAE) at the University of Arizona have been developing and conducting research on the effectiveness of instructional strategies and materials that are explicitly designed to challenge students' naïve ideas and intellectually engage their thinking at a deep level in the traditional lecture classroom. The results of this work show that dramatic improvement in student understanding can be made from increased use of interactive learning strategies. These improvements are shown to be independent of institution type or class size, but appear to be strongly influenced by the quality of the instructor's implementation. In addition, we find that the positive effects of interactive learning strategies apply equally to men and women, across ethnicities, for students with all levels of prior mathematical preparation and physical science course experience, independent of GPA, and regardless of primary language. These results powerfully illustrate that all students can benefit from the effective implementation of interactive learning strategies.

  18. The contribution of quality to health services. Application of the quality management system ISO 9001:2008 in Intensive Care Unit of the General Hospital of Larissa

    Directory of Open Access Journals (Sweden)

    Dimitrios Patsios

    2014-10-01

    Full Text Available In our country there have been many efforts in recent years to introduce laws that lead to the introduction of the concept of quality in the field of public hospitals. The implementation of health quality systems contributes to health care improvement, while the assessment of quality services is a basic tool in quality management. Purpose: The purpose of the study was to describe the benefits that can be gained by a public institute of health when a quality model is applied. Material and methods: This paper focus on the application of the ISO 9001:2008 standard in the Intensive Care Unit of the General Hospital of Larissa during the years 2010-2012. The results and benefits of its implementation, recorded by measuring satisfaction of the relatives of the patients. The questionnaire Family Satisfaction with Care in the Intensive Care Unit (FS-ICU 24 and quality indicators were applied. The study sample was all the relatives of the patients hospitalized in ICU during 2010-2012. Descriptive statistics was performed. Results: Quality indicators were considerably improved after ISO implementation with SMR falling to 35% in 2012 (from 58% in 2007, thus being one of the lowest in Greece and below European ICU’s SMR mean value. Over 80% of patients’ relatives answered that Nursing and Medical care was “excellent” and over 10% characterized it as “very good”. Family members’ total satisfaction surpassed 90%. Medical and Nursing care were highly appreciated by family members (very positive attitude expressed by over 90% of participants and satisfaction from nursing services approaches 100%. Conclusion: The implementation of quality systems in healthcare organizations is not easy and has many dimensions. However, it offers competitive advantage, improves the efficiency and effectiveness of the health care service providers and substantially contributes to the improvement of the delivered heath care.

  19. Active Mines and Mineral Processing Plants in the United States in 2003

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This data set includes mineral and metal operations in the United States. The data represent commodities monitored by the National Minerals Information Center of...

  20. Task-dependent activity of motor unit populations in feline ankle extensor muscles

    NARCIS (Netherlands)

    Hodson-Tole, E.F.; Pantall, A.; Maas, H.; Farrell, B.J.; Gregor, R.J.; Prilutsky, B.I.

    2012-01-01

    Understanding the functional significance of the morphological diversity of ammalian skeletal muscles is limited by technical difficulties of estimating the contribution of motor units with different properties to unconstrained motor behaviours. Recently developed wavelet and principal components an

  1. Active Mines and Mineral Processing Plants in the United States in 2003

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This data set includes mineral and metal operations in the United States. The data represent commodities monitored by the National Minerals Information Center of the...

  2. First results about recovery of walking function in patients with intensive care unit-acquired muscle weakness from the General Weakness Syndrome Therapy (GymNAST) cohort study.

    Science.gov (United States)

    Mehrholz, Jan; Mückel, Simone; Oehmichen, Frank; Pohl, Marcus

    2015-12-23

    To describe the time course of recovery of walking function and other activities of daily living in patients with intensive care unit (ICU)-acquired muscle weakness. This is a cohort study. We included critically ill patients with ICU-acquired muscle weakness. Post-acute ICU and rehabilitation units in Germany. We measured walking function, muscle strength, activities in daily living, motor and cognitive function. We recruited 150 patients (30% female) who fulfilled our inclusion and exclusion criteria. The primary outcome recovery of walking function was achieved after a median of 28.5 days (IQR=45) after rehabilitation onset and after a median of 81.5 days (IQR=64) after onset of illness. Our final multivariate model for recovery of walking function included two clinical variables from baseline: the Functional Status Score ICU (adjusted HR=1.07 (95% CI 1.03 to 1.12) and the ability to reach forward in cm (adjusted HR=1.02 (95% CI 1.00 to 1.04). All secondary outcomes but not pain improved significantly in the first 8 weeks after study onset. We found good recovery of walking function for most patients and described the recovery of walking function of people with ICU-acquired muscle weakness. Sächsische Landesärztekammer EK-BR-32/13-1; DRKS00007181, German Register of Clinical Trials. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  3. The Use of Molecular Modeling as "Pseudoexperimental" Data for Teaching VSEPR as a Hands-On General Chemistry Activity

    Science.gov (United States)

    Martin, Christopher B.; Vandehoef, Crissie; Cook, Allison

    2015-01-01

    A hands-on activity appropriate for first-semester general chemistry students is presented that combines traditional VSEPR methods of predicting molecular geometries with introductory use of molecular modeling. Students analyze a series of previously calculated output files consisting of several molecules each in various geometries. Each structure…

  4. Social safety, general health and physical activity: changes in neighbourhood safety and the role of social cohesion.

    NARCIS (Netherlands)

    Ruijsbroek, A.; Droomers, M.; Groenewegen, P.P.; Hardyns, W.; Stronks, K.

    2015-01-01

    The aim of this study was to examine whether changes over time in reported area crime and perceived area safety were related to self-rated general health and physical activity (PA), in order to provide support for a causal relationship between social safety and health. Additionally, we investigated

  5. Removal of Aromatic Pollutant Surrogate from Water by Recyclable Magnetite-Activated Carbon Nanocomposite: An Experiment for General Chemistry

    Science.gov (United States)

    Furlan, Ping Y.; Melcer, Michael E.

    2014-01-01

    A general chemistry laboratory experiment using readily available chemicals is described to introduce college students to an exciting class of nanocomposite materials. In a one-step room temperature synthetic process, magnetite nanoparticles are embedded onto activated carbon matrix. The resultant nanocomposite has been shown to combine the…

  6. The Use of Molecular Modeling as "Pseudoexperimental" Data for Teaching VSEPR as a Hands-On General Chemistry Activity

    Science.gov (United States)

    Martin, Christopher B.; Vandehoef, Crissie; Cook, Allison

    2015-01-01

    A hands-on activity appropriate for first-semester general chemistry students is presented that combines traditional VSEPR methods of predicting molecular geometries with introductory use of molecular modeling. Students analyze a series of previously calculated output files consisting of several molecules each in various geometries. Each structure…

  7. Social safety, general health and physical activity: changes in neighbourhood safety and the role of social cohesion.

    NARCIS (Netherlands)

    Ruijsbroek, A.; Droomers, M.; Groenewegen, P.P.; Hardyns, W.; Stronks, K.

    2015-01-01

    The aim of this study was to examine whether changes over time in reported area crime and perceived area safety were related to self-rated general health and physical activity (PA), in order to provide support for a causal relationship between social safety and health. Additionally, we investigated

  8. Activity of neutrophil β-glucuronidase in diabetic and nondiabetic patients with chronic generalized periodontitis and healthy subjects.

    Science.gov (United States)

    Surna, Algimantas; Sakalauskienė, Jurgina; Gleiznys, Alvydas; Ivanauskienė, Eglė; Saferis, Viktoras

    2011-01-01

    OBJECTIVE. The aim of the study was to establish the dynamics of β-glucuronidase activity in subjects suffering from type 1 diabetes and chronic untreated generalized periodontitis, subjects suffering from chronic untreated generalized periodontitis only, and control subjects not suffering from generic diseases with healthy periodontal tissue. MATERIAL AND METHODS. The study involved 165 19-50-year-old subjects who were divided into three groups: healthy subjects (n=55), subjects with chronic untreated generalized periodontitis (n=55), and subjects with type 1 diabetes and chronic untreated generalized periodontitis (n=55). Neutrophilic leukocytes of peripheral venous blood were exposed to bacterial stimuli: opsonized zymosan, nonopsonized Staphylococcus aureus, and prodigiosan. The activity of β-glucuronidase was determined by the spectrofluorimetry method. RESULTS. The diagnostic value of changes in β-glucuronidase activity of neutrophilic leukocytes markedly increased in all study groups after stimulation of neutrophilic leukocytes by opsonized zymosan, nonopsonized Staphylococcus aureus, and prodigiosan as compared to control media not exposed to any stimulus (Pperiodontal pathology markers and the activity of β-glucuronidase of neutrophilic leukocytes in incubated media in patients with type 1 diabetes mellitus and periodontitis was found under the effect of nonopsonized Staphylococcus aureus. CONCLUSIONS. If periodontal impairment is severe, diabetes mellitus possibly causes a faster destruction of the periodontal tissue and presents a higher risk of periodontitis for patients with diabetes.

  9. Factors related to positive and negative outcomes in psychiatric inpatients in a General Hospital Psychiatric Unit: a proposal for an outcomes index

    Directory of Open Access Journals (Sweden)

    HUGO KARLING MORESCHI

    2015-02-01

    Full Text Available Background General Hospital Psychiatric Units have a fundamental importance in the mental health care systems. However, there is a lack of studies regarding the level of improvement of patients in this type of facility. Objective To assess factors related to good and poor outcomes in psychiatric inpatients using an index composed by clinical parameters easily measured. Methods Length of stay (LOS, Global Assessment of Functioning (variation and at discharge and Clinical Global Impression (severity and improvement were used to build a ten-point improvement index (I-Index. Records of psychiatric inpatients of a general hospital during an 18-month period were analyzed. Three groups (poor, intermediate and good outcomes were compared by univariate and multivariate models according to clinical and sociodemographic variables. Results Two hundred and fifty patients were included, with a percentage in the groups with poor, regular and good outcomes of 16.4%, 59,6% and 24.0% respectively. Poor outcome at the discharge was associated mainly with lower education, transient disability, antipsychotics use, chief complaint “behavioral change/aggressiveness” and psychotic features. Multivariate analysis found a higher OR for diagnoses of “psychotic disorders” and “personality disorders” and others variables in relation to protective categories in the poor outcome group compared to the good outcome group. Discussion Our I-Index proved to be an indicator of that allows an easy and more comprehensive evaluation to assess outcomes of inpatients than just LOS. Different interventions addressed to conditions such as psychotic disorders and disruptive chief complaints are necessary.

  10. Involving the public in general practice in an urban district: levels and type of activity and perceptions of obstacles.

    Science.gov (United States)

    Brown, Ian

    2000-07-01

    This paper reports on a study of the level and type of activity used to involve the public in general practice in a city district in the north of England. The association of these activities with features of the general practice organisation and environment were studied. Service providers' perceptions of obstacles were also studied. Data were collected in a survey of all general practice organisations in the district using a postal questionnaire completed by a practice manager. Interviews were conducted with health service managers responsible for primary care development in the district. The study showed that the district had a good track record for innovation in primary care development and in giving emphasis to developing public involvement. However, it also showed that it was difficult to translate policy rhetoric into practical initiatives at the general practice level without evidence of models of best practice, and with limited resources. The survey had a high response of over 84%. It showed that levels of activity were low across the district and only a small minority of general practice teams had undertaken a range of activities to involve the public. The socio-economic environment did not appear to be a factor, but small practices (one or two partners and/or practice population under 3000) were much less likely to develop activities. Pressures of existing workload, lack of resources and public apathy were given as among the main obstacles by survey respondents. The study indicates the challenges faced by Primary Care Groups in developing strands of public involvement. Primary care teams need a clear strategic framework, models of best practice, and adequate resources to manage, change and develop initiatives.

  11. Patterns of muscle activation during generalized tonic and tonic–clonic epileptic seizures

    DEFF Research Database (Denmark)

    Conradsen, Isa; Wolf, Peter; Sams, Thomas

    2011-01-01

    was recorded from the deltoid muscles, on both sides, during 63 seizures from 20 patients with epilepsy (10 with generalized tonic and 10 with tonic–clonic seizures). Twenty age‐ and gender‐matched normal controls simulated 100 generalized tonic seizures. To characterize the signal properties we calculated...... the root mean square (RMS) of the amplitudes, the median frequency (MF), and the coherence. Based on the spectrograms of both epileptic and simulated seizures, we chose to determine the relative spectral power (RP) in the higher (100–500 Hz) frequency domain. Key Findings: During the tonic seizures...

  12. Exposed to events that never happen: Generalized unsafety, the default stress response, and prolonged autonomic activity.

    Science.gov (United States)

    Brosschot, Jos F; Verkuil, Bart; Thayer, Julian F

    2017-03-01

    Based on neurobiological and evolutionary arguments, the generalized unsafety theory of stress (GUTS) hypothesizes that the stress response is a default response, and that chronic stress responses are caused by generalized unsafety (GU), independent of stressors or their cognitive representation. Three highly prevalent conditions are particularly vulnerable to becoming 'compromised' in terms of GU, and carry considerable health risks: Thus, GUTS critically revises and expands stress theory, by focusing on safety instead of threat, and by including risk factors that have hitherto not been attributed to stress.

  13. Trace minerals status and antioxidative enzyme activity in dogs with generalized demodecosis.

    Science.gov (United States)

    Beigh, S A; Soodan, J S; Singh, R; Khan, A M

    2013-11-15

    The present study was aimed to determine the levels of trace elements zinc, copper, iron, erythrocyte oxidant/anti-oxidant balance, vitamin C and β-carotene in dogs with generalized demodecosis. A total of 24 dogs with clinically established diagnosis of generalized demodecosis and 6 dogs as control were included in the study. In comparison to healthy control, zinc and copper levels were significantly (Pdemodecosis, whereas iron levels were significantly (P0.05; rs=-0.54, Pdemodecosis in dogs is associated with significant alteration in trace elements and oxidant/anti-oxidant imbalance and this imbalance might be secondary to changes caused by demodectic mange.

  14. Ionic liquid-impregnated activated carbon for biohydrogen purification in an adsorption unit

    Science.gov (United States)

    Yusuf, N. Y.; Masdar, M. S.; Isahak, W. N. R. W.; Nordin, D.; Husaini, T.; Majlan, E. H.; Rejab, S. A. M.; Chew, C. L.

    2017-06-01

    Biological methods for hydrogen production (biohydrogen) are known as energy intensive and can be operated at ambient temperature and pressure; however, consecutive productions such as purification and separation processes still remain challenging in the industry. Various techniques are used to purify and separate hydrogen. These techniques include the use of sorbents/solvents, membranes and cryogenic distillation. In this study, carbon dioxide (CO2) was purified and separated from biohydrogen to produce high purity hydrogen gas. CO2 capture was studied using the activated carbon (AC) modified with the ionic liquid (IL) choline chloride as adsorbent. The physical and chemical properties of the adsorbents were characterized through XRD, FTIR, SEM-EDX, TGA, and BET analyses. The effects of IL loading, flow rate, temperature, and gas mixture were also investigated based on the absorption and desorption of CO2. The CO2 level in the biohydrogen composition was analyzed using a CO2 gas analyzer. The SEM image indicated that the IL homogeneously covered the AC surface. High IL dispersion inlet enhanced the capability of the adsorbent to capture CO2 gas. The thermal stability and presence of the functionalized group of ILs on AC were analyzed by TGA and FTIR techniques, respectively. CO2 adsorption experiments were conducted using a 1 L adsorber unit. Hence, adsorption technologies exhibit potential for biohydrogen purification and mainly affected by adsorbent ability and operating parameters. This research presents an improved biohydrogen technique based on adsorption technology with novel adsorbents. Two different types of commercial CO2 adsorbents were used in the experiment. Results show that the IL/AC exhibited properties suitable for CO2 adsorption. The IL/AC sample presented a high CO2 uptake of 30 wt. % IL when treated at 30 °C for 6 h under a flow rate of 1 L/min. The presence of IL increased the selectivity of CO2 removal during the adsorption process. This IL

  15. Sustainability in a global context: How does local factor affect the outcomes of CSR activities in international business units?

    DEFF Research Database (Denmark)

    Thomsen, Christa; Lauring, Jakob

    In recent years CSR has become increasingly important for the activities and branding of MNCs. While some studies have investigated CSR management and branding in domestic situations, fewer studies exist in the case of international business units (subsidiaries, joint ventures, and franchises...... as CSR branding outcomes). Our findings show that local values were positively associated with external CSR engagement and that employee relations were positively related to both internal and external CSR engagement. None of the local factors were significantly associated with CSR branding outcomes......). In this study, we use a sample consisting of 119 Danish business units that are located in China. We set out to investigate the relationship between local factors (the local business unit’s Chinese values and internal employee relations in the unit) and CSR outcomes (internal and external CSR engagement as well...

  16. Identification of general linear relationships between activation energies and enthalpy changes for dissociation reactions at surfaces.

    Science.gov (United States)

    Michaelides, Angelos; Liu, Z-P; Zhang, C J; Alavi, Ali; King, David A; Hu, P

    2003-04-02

    The activation energy to reaction is a key quantity that controls catalytic activity. Having used ab inito calculations to determine an extensive and broad ranging set of activation energies and enthalpy changes for surface-catalyzed reactions, we show that linear relationships exist between dissociation activation energies and enthalpy changes. Known in the literature as empirical Brønsted-Evans-Polanyi (BEP) relationships, we identify and discuss the physical origin of their presence in heterogeneous catalysis. The key implication is that merely from knowledge of adsorption energies the barriers to catalytic elementary reaction steps can be estimated.

  17. Single-unit activity in piriform cortex during slow-wave state is shaped by recent odor experience.

    Science.gov (United States)

    Wilson, Donald A

    2010-02-03

    Memory and its underlying neural plasticity play important roles in sensory discrimination and cortical pattern recognition in olfaction. Given the reported function of slow-wave sleep states in neocortical and hippocampal memory consolidation, we hypothesized that activity during slow-wave states within the piriform cortex may be shaped by recent olfactory experience. Rats were anesthetized with urethane and allowed to spontaneously shift between slow-wave and fast-wave states as recorded in local field potentials within the anterior piriform cortex. Single-unit activity of piriform cortical layer II/III neurons was recorded simultaneously. The results suggest that piriform cortical activity during slow-wave states is shaped by recent (several minutes) odor experience. The temporal structure of single-unit activity during slow waves was modified if the animal had been stimulated with an odor within the receptive field of that cell. If no odor had been delivered, the activity of the cell during slow-wave activity was stable across the two periods. The results demonstrate that piriform cortical activity during slow-wave state is shaped by recent odor experience, which could contribute to odor memory consolidation.

  18. A study of the kinetics and the effect of trace elements on mixed anaerobic fermentative biogas production by ternary quadratic general rotary unitized design

    Directory of Open Access Journals (Sweden)

    Chenxiao Zhang

    2016-01-01

    Full Text Available In this study the effect of trace elements on methanogenesis was investigated during mixed anaerobic fermentation using a single-factor experiment in the present study. The most effective concentrations of Fe0, Fe2+, Co2+ and Ni2+ that were added were 1500, 250, 0.3 and 0.6 mg/L, respectively. The optimal trace element combination was 0.58 mg/L Ni2+, 1200 mg/L Fe0 and 0.34 mg/L Co2+ by the ternary quadratic general rotary unitized design method. The degree of influence exerted by trace elements on the cumulative methane yields decreased in the order of Ni2+, Fe0 and Co2+, and the maximum CH4 yield was 241.6 mL/g volatile solids (VS, according to a regression equation. The non-dissolved organic carbon hydrolytic process showed a good fit with the first-order kinetic model. The maximum value of CH4 was 312.87 mL/g VS. Compared to the control, the bioconversion efficiencies of CH4 and CO2 production increased by 36.76% and 74.50%, respectively, at the optimal trace element combination. The obtained results provide new knowledge for improvements in the efficiency of anaerobic fermentation biogas production.

  19. 基于广义Benders分解的启发式机组组合优化%A Generalized Benders Decomposition Based Heuristic Algorithm for Unit Commitment

    Institute of Scientific and Technical Information of China (English)

    李颖浩; 郭瑞鹏

    2012-01-01

    电力系统机组组合问题是一个高维、离散、非线性的工程优化问题。提出了一种基于Benders分解的启发式算法。该算法一方面充分利用研究时段负荷曲线的特征,将问题进行解耦,减小被研究问题的规模。另一方面,利用Benders分解算法在混合整数规划中的有效性,提高了解决问题的效率。算例表明该方法效率高、结果稳定,有较好的实用价值。%Unit commitment (UC) of power system is a high dimensional, nonlinear and mixed-integer engineering optimization problem. To solve this problem a generalized Benders decomposition based heuristic algorithm is proposed. On the one hand the characteristics of load curve in the time-interval being researched are fully utilized to decouple the problem and to decrease the scale of the problem, on the other hand using the effectiveness of Benders algorithm is solving mixed-integer programming problem the efficiency of solving the problem is improved. Results of calculation example show that the proposed algorithm is efficient and practicable.

  20. Barriers and challenges in seeking psychiatric intervention in a General Hospital, by the collaborative child response unit, (A multidisciplinary team approach to handling child abuse A qualitative analysis

    Directory of Open Access Journals (Sweden)

    Vyjayanthi Kanugodu Srinivasa Subramaniyan

    2017-01-01

    Full Text Available Child abuse is a serious criminal act against children in our country and punishable according to protection of children from sexual offenses act 2012. No one agency has the ability to respond completely to the abuse. Hence a multidisciplinary team approach was developed in India. Aim is to narrate the collaborative effort among the multiple disciplines in a general hospital to deliver child protection services and explore the barriers to integrate psychiatric services. Methodology: Members of the team were recruited from different disciplines and trained by experts. A mission statement, protocol to assess the victims and provide treatment was formulated as an algorithm. The barriers to psychiatric treatment among the stakeholders were analyzed using framework method of qualitative analysis. Results (After 20 months the unit received 27 referrals in 20 months, 24 females, and 3 males. Age of the victims was between 8 months and 17 years. Two cases found to be physically abused. Penetrative sexual abuse was found in 23 cases, pregnant victims were 4. Most referrals were by police, trafficking found in 6 cases. Discussion: It was possible to provide multidisciplinary care to the victims and families. Recurrent themes of barriers to psychiatric treatment were stigma, victim blaming; focus on termination of pregnancy, minimization of abuse in males by stakeholders. Conclusion is collaboration needs more effort to integrate psychiatric services but can minimize the reduplication of services.

  1. Breast Cancer Profile in a Group of Patients Followed up at the Radiation Therapy Unit of the Yaounde General Hospital, Cameroon

    Directory of Open Access Journals (Sweden)

    J. D. Kemfang Ngowa

    2011-01-01

    Full Text Available Objective. To describe the profile of breast cancer in the patients attending the radiation therapy unit of Yaounde General Hospital. Method. From 1989 to 2009, we conducted a descriptive retrospective study based on the register and medical records of patients. Results. During the study period, 531 breast cancer patients were recorded of which 0.75% were male. Age range was 18 to 82 years, with a mean of 45.17 years. Out of these, 66.1% were less than 50 years old and 31.9% less than 40. Self detection was the discovery method in most cases (95.34% of patients. Mean delay before presentation at hospital was 10.35 months, and 54.94% had used traditional medicine before medical evaluation. Metastasis and locally advanced breast cancer at diagnosis were present in 08.13% and 62.78%, respectively. Mastectomy was used in 88.08% of patients. Conclusion. The study reinforces the position occupied by late presentation and advanced stage at diagnosis of breast cancer profile in developing countries.

  2. 图形处理器在通用计算中的应用%Application of graphics processing unit in general purpose computation

    Institute of Scientific and Technical Information of China (English)

    张健; 陈瑞

    2009-01-01

    基于图形处理器(GPU)的计算统一设备体系结构(compute unified device architecture,CUDA)构架,阐述了GPU用于通用计算的原理和方法.在Geforce8800GT下,完成了矩阵乘法运算实验.实验结果表明,随着矩阵阶数的递增,无论是GPU还是CPU处理,速度都在减慢.数据增加100倍后,GPU上的运算时间仅增加了3.95倍,而CPU的运算时间增加了216.66倍.%Based on the CUDA (compute unified device architecture) of GPU (graphics processing unit), the technical fundamentals and methods for general purpose computation on GPU are introduced. The algorithm of matrix multiplication is simulated on Geforce8800 GT. With the increasing of matrix order, algorithm speed is slowed either on CPU or on GPU. After the data quantity increases to 100 times, the operation time only increased in 3.95 times on GPU, and 216.66 times on CPU.

  3. Barriers and Challenges in Seeking Psychiatric Intervention in a General Hospital, by the Collaborative Child Response Unit, (A Multidisciplinary Team Approach to Handling Child Abuse) A Qualitative Analysis

    Science.gov (United States)

    Subramaniyan, Vyjayanthi Kanugodu Srinivasa; Mital, Anukant; Rao, Chandrika; Chandra, Girish

    2017-01-01

    Child abuse is a serious criminal act against children in our country and punishable according to protection of children from sexual offenses act 2012. No one agency has the ability to respond completely to the abuse. Hence a multidisciplinary team approach was developed in India. Aim is to narrate the collaborative effort among the multiple disciplines in a general hospital to deliver child protection services and explore the barriers to integrate psychiatric services. Methodology: Members of the team were recruited from different disciplines and trained by experts. A mission statement, protocol to assess the victims and provide treatment was formulated as an algorithm. The barriers to psychiatric treatment among the stakeholders were analyzed using framework method of qualitative analysis. Results (After 20 months) the unit received 27 referrals in 20 months, 24 females, and 3 males. Age of the victims was between 8 months and 17 years. Two cases found to be physically abused. Penetrative sexual abuse was found in 23 cases, pregnant victims were 4. Most referrals were by police, trafficking found in 6 cases. Discussion: It was possible to provide multidisciplinary care to the victims and families. Recurrent themes of barriers to psychiatric treatment were stigma, victim blaming; focus on termination of pregnancy, minimization of abuse in males by stakeholders. Conclusion is collaboration needs more effort to integrate psychiatric services but can minimize the reduplication of services.

  4. Can systemically generated reactive oxygen species help to monitor disease activity in generalized vitiligo? A pilot study

    Directory of Open Access Journals (Sweden)

    Richeek Pradhan

    2014-01-01

    Full Text Available Background: Generalized vitiligo is a disease with unpredictable bursts of activity, goal of treatment during the active phase being to stabilize the lesions. This emphasizes the need for a prospective marker for monitoring disease activity to help decide the duration of therapy. Aims and Objectives: In the present study, we examined whether reactive oxygen species (ROS generated in erythrocytes can be translated into a marker of activity in vitiligo. Materials and Methods: Level of intracellular ROS was measured flow cytometrically in erythrocytes from venous blood of 21 patients with generalized vitiligo and 21 healthy volunteers using the probe dichlorodihydrofluorescein diacetate. Results: The levels of ROS differed significantly between patients and healthy controls, as well as between active versus stable disease groups. In the active disease group, ROS levels were significantly lower in those being treated with systemic steroids than those that were not. ROS levels poorly correlated with disease duration or body surface area involved. Conclusion: A long-term study based on these findings can be conducted to further validate the potential role of ROS in monitoring disease activity vitiligo.

  5. Infrared and Raman Spectroscopy: A Discovery-Based Activity for the General Chemistry Curriculum

    Science.gov (United States)

    Borgsmiller, Karen L.; O'Connell, Dylan J.; Klauenberg, Kathryn M.; Wilson, Peter M.; Stromberg, Christopher J.

    2012-01-01

    A discovery-based method is described for incorporating the concepts of IR and Raman spectroscopy into the general chemistry curriculum. Students use three sets of springs to model the properties of single, double, and triple covalent bonds. Then, Gaussian 03W molecular modeling software is used to illustrate the relationship between bond…

  6. 77 FR 8880 - Agency Information Collection Activities; Proposed Collection; Comment Request; General Licensing...

    Science.gov (United States)

    2012-02-15

    ... Collection; Comment Request; General Licensing Provisions; Section 351(k) Biosimilar Applications AGENCY... for an application for a proposed biosimilar product and an application for a supplement for a...) Biosimilar Applications On March 23, 2010, the President signed into law the Patient Protection...

  7. Infrared and Raman Spectroscopy: A Discovery-Based Activity for the General Chemistry Curriculum

    Science.gov (United States)

    Borgsmiller, Karen L.; O'Connell, Dylan J.; Klauenberg, Kathryn M.; Wilson, Peter M.; Stromberg, Christopher J.

    2012-01-01

    A discovery-based method is described for incorporating the concepts of IR and Raman spectroscopy into the general chemistry curriculum. Students use three sets of springs to model the properties of single, double, and triple covalent bonds. Then, Gaussian 03W molecular modeling software is used to illustrate the relationship between bond…

  8. Sensitivity of future continental United States water deficit projections to general circulation models, the evapotranspiration estimation method, and the greenhouse gas emission scenario

    Science.gov (United States)

    Chang, Seungwoo; Graham, Wendy D.; Hwang, Syewoon; Muñoz-Carpena, Rafael

    2016-08-01

    Projecting water deficit under various possible future climate scenarios depends on the choice of general circulation model (GCM), reference evapotranspiration (ET0) estimation method, and Representative Concentration Pathway (RCP) trajectory. The relative contribution of each of these factors must be evaluated in order to choose an appropriate ensemble of future scenarios for water resources planning. In this study variance-based global sensitivity analysis and Monte Carlo filtering were used to evaluate the relative sensitivity of projected changes in precipitation (P), ET0, and water deficit (defined here as P-ET0) to choice of GCM, ET0 estimation method, and RCP trajectory over the continental United States (US) for two distinct future periods: 2030-2060 (future period 1) and 2070-2100 (future period 2). A total of 9 GCMs, 10 ET0 methods, and 3 RCP trajectories were used to quantify the range of future projections and estimate the relative sensitivity of future projections to each of these factors. In general, for all regions of the continental US, changes in future precipitation are most sensitive to the choice of GCM, while changes in future ET0 are most sensitive to the choice of ET0 estimation method. For changes in future water deficit, the choice of GCM is the most influential factor in the cool season (December-March), and the choice of ET0 estimation method is most important in the warm season (May-October) for all regions except the Southeast US, where GCMs and ET0 have approximately equal influence throughout most of the year. Although the choice of RCP trajectory is generally less important than the choice of GCM or ET0 method, the impact of RCP trajectory increases in future period 2 over future period 1 for all factors. Monte Carlo filtering results indicate that particular GCMs and ET0 methods drive the projection of wetter or drier future conditions much more than RCP trajectory; however, the set of GCMs and ET0 methods that produce wetter or

  9. Active and Reserve Unit Costs: DOD Report to Congress Generally Addressed the Statutory Requirements but Lacks Detail

    Science.gov (United States)

    2014-07-31

    National Defense Authorization Act for Fiscal Year 2012, Section 1080A, issued in January 2012, states that such reductions must be balanced with...preparation for future challenges and protection of the broad range of U.S. national security interests. One key to achieving this balance is determining the...addressed the statutory requirements, we used a scorecard methodology in which two analysts independently assessed the extent to which the report’s

  10. General second order complete active space self-consistent-field solver for large-scale systems

    CERN Document Server

    Sun, Qiming

    2016-01-01

    One challenge of the complete active space self-consistent field (CASSCF) program is to solve the transition metal complexes which are typically medium or large-size molecular systems with large active space. We present an AO-driven second order CASSCF solver to efficiently handle systems which have a large number of AO functions and many active orbitals. This solver allows user to replace the active space Full CI solver with any multiconfigurational solver without breaking the quadratic convergence feature. We demonstrate the capability of the CASSCF solver with the study of Fe(ii)-porphine ground state using DMRG-CASSCF method for 22 electrons in 27 active orbitals and 3000 basis functions.

  11. Analysis of the Activity of Fiscal Control Carried out by the General Directorate of Public Financem Maramures

    Directory of Open Access Journals (Sweden)

    Constantin Cucosel

    2012-11-01

    Full Text Available Presently, Fiscal control activities are carried out by the bodies of fiscal control within the Ministry of Public Finance and its territorial units called fiscal control bodies, and by the specialized services of the local administrative authorities in order to handle local duties and taxes. The fiscal control includes a set of activities whose purpose is to verify the authenticity, legitimacy and sincerity of the tax statements, to verify that the taxpayers comply with their budget obligations and activities of investigation and finding tax evasion. The taxpayers – physical persons or legal entities, foreign and domestic, and associations with no legal entity status are subject to fiscal control if they have budget obligations.

  12. Effect of generalized joint hypermobility on knee function and muscle activation in children and adults

    DEFF Research Database (Denmark)

    Jensen, Bente Rona; Olesen, Annesofie T.; Pedersen, Mogens Theisen

    2013-01-01

    were evaluated in 39 children and 36 adults during isometric knee extension and flexion. Subjects performed isometric maximum contractions, submaximal contractions at 25% maximum voluntary contraction (MVC), and explosive contractions. Results: Agonist activation was reduced, and coactivation ratio...

  13. 78 FR 69118 - Information Collection Activities: General; Proposed Collection; Comment Request

    Science.gov (United States)

    2013-11-18

    ... operations conducted under a lease, right-of-way, or a right-of-use and easement. Operations on the OCS must... activities. We consider these to be usual and customary and took that into account in estimating the burden...

  14. General theory for spontaneous emission in active dielectric microstructures: Example of a fiber amplifier

    DEFF Research Database (Denmark)

    Søndergaard, Thomas; Tromborg, Bjarne

    2001-01-01

    A model for spontaneous emission in active dielectric microstructures is given in terms of the classical electric field Green's tensor and the quantum-mechanical operators for the generating currents. A formalism is given for calculating the Green's tensor, which does not rely on the existence......, transition frequency, and vector orientation of a spatially localized current source. Radiation patterns are studied using a Poynting vector approach taking into account amplification or absorption from an active medium in the fiber....

  15. Recess Activity and General Health Status among Iranian Elementary Schools’ Pupils

    Directory of Open Access Journals (Sweden)

    Abdolreza Shaghaghi

    2013-06-01

    Full Text Available Background: Regular and daily physical activity during childhood and at school is one of the important part of requirements of normal growth, development and well-being. To achieve physical activity promotion among school child aged population recess as outside of class time efforts is scheduled and allows students to engage in physical and social activities. The purpose of the present study was to assess recess activities as well as status of physical activities among a sample of Iranian students at the pri¬mary schools.Methods: This cross-sectional study was performed in four randomly se¬lected schools from a list of 26 elementary schools in March, 2012 in the city of Shahindej, located in North-west of Iran. Participants were 439 (10–12 years elementary schools’. Physical activity level by self-reporting, mental health using the parent-completed Child Health Questionnaire, and happiness was assessed using a Persian translated version of the Subjective Happiness Scale. Hierarchical logistic regression analysis was applied in two steps using the enter method to analyze data in the SPSS version 17.Results: Backward logistic regression analysis showed that gender of the parent who answered the study questions, father’s education, educational grade of children, BMI, physical function, physical health, health status of the children and family function were significantly related to the children’s physical activity level.Conclusion: Promoting parents’ awareness and schools’ staff about im¬portance of physical activities especially in recess times must be an impor¬tant part of school and community mental health promotion programs.

  16. Chelating ruthenium phenolate complexes: synthesis, general catalytic activity, and applications in olefin metathesis polymerization.

    Science.gov (United States)

    Kozłowska, Anna; Dranka, Maciej; Zachara, Janusz; Pump, Eva; Slugovc, Christian; Skowerski, Krzysztof; Grela, Karol

    2014-10-20

    Cyclic Ru-phenolates were synthesized, and these compounds were used as olefin metathesis catalysts. Investigation of their catalytic activity pointed out that, after activation with chemical agents, these catalysts promote ring-closing metathesis (RCM), enyne and cross-metathesis (CM) reactions, including butenolysis, with good results. Importantly, these latent catalysts are soluble in neat dicyclopentadiene (DCPD) and show good applicability in ring-opening metathesis polymeriyation (ROMP) of this monomer.

  17. Generalization of the Activated Complex Theory of Reaction Rates. I. Quantum Mechanical Treatment

    Science.gov (United States)

    Marcus, R. A.

    1964-01-01

    In its usual form activated complex theory assumes a quasi-equilibrium between reactants and activated complex, a separable reaction coordinate, a Cartesian reaction coordinate, and an absence of interaction of rotation with internal motion in the complex. In the present paper a rate expression is derived without introducing the Cartesian assumption. The expression bears a formal resemblance to the usual one and reduces to it when the added assumptions of the latter are introduced.

  18. Action unit classification using active appearance models and conditional random fields

    NARCIS (Netherlands)

    Van der Maaten, L.J.P.; Hendriks, E.A.

    2011-01-01

    In this paper, we investigate to what extent modern computer vision and machine learning techniques can assist social psychology research by automatically recognizing facial expressions. To this end, we develop a system that automatically recognizes the action units defined in the facial action codi

  19. 76 FR 28058 - BOEMRE Information Collection Activity: 1010-0068, Unitization, Extension of a Collection...

    Science.gov (United States)

    2011-05-13

    ...: 1010-0068, Unitization, Extension of a Collection; Comment Request AGENCY: Bureau of Ocean Energy... collection (1010-0068). SUMMARY: To comply with the Paperwork Reduction Act of 1995 (PRA), BOEMRE is inviting... Blundon, 381 Elden Street, MS-4024, Herndon, Virginia 20170-4817. Please reference ICR 1010-0068 in...

  20. Our Environment. Language Arts Theme Units, Volume I. Cross Curricular Activities for Primary Grades.

    Science.gov (United States)

    McAllister, Elizabeth A.; Hildebrand, Joan M.; Ericson, Joann H.

    Suggesting that students in the primary grades can explore the world around them and practice valuable skills in spelling, reading, writing, communication, and language, this book presents cross-curricular units on the environment that reach diverse needs by working through emotional memory, deductive reasoning, and multiple intelligences.…

  1. People Around Us. Language Arts Theme Units, Volume V. Cross Curricular Activities for Primary Grades.

    Science.gov (United States)

    McAllister, Elizabeth A.; Hildebrand, Joan M.; Ericson, Joann H.

    Suggesting that students in the primary grades can explore the world around them and practice valuable skills in spelling, reading, writing, communication, and language, this book presents cross-curricular units on "people around us" that reach diverse needs by working through emotional memory, deductive reasoning, and multiple intelligences.…

  2. Intriguing Animals. Language Arts Theme Units, Volume IV. Cross Curricular Activities for Primary Grades.

    Science.gov (United States)

    McAllister, Elizabeth A.; Hildebrand, Joan M.; Ericson, Joann H.

    Suggesting that students in the primary grades can explore the world around them and practice valuable skills in spelling, reading, writing, communication, and language, this book presents cross-curricular units on intriguing animals that reach diverse needs by working through emotional memory, deductive reasoning, and multiple intelligences.…

  3. Action unit classification using active appearance models and conditional random fields

    NARCIS (Netherlands)

    Van der Maaten, L.J.P.; Hendriks, E.A.

    2011-01-01

    In this paper, we investigate to what extent modern computer vision and machine learning techniques can assist social psychology research by automatically recognizing facial expressions. To this end, we develop a system that automatically recognizes the action units defined in the facial action codi

  4. Action unit classification using active appearance models and conditional random fields

    NARCIS (Netherlands)

    Van der Maaten, L.J.P.; Hendriks, E.A.

    2011-01-01

    In this paper, we investigate to what extent modern computer vision and machine learning techniques can assist social psychology research by automatically recognizing facial expressions. To this end, we develop a system that automatically recognizes the action units defined in the facial action

  5. Corrective Action Management Unit Report of Post-Closure Care Activities Calendar Year 2016.

    Energy Technology Data Exchange (ETDEWEB)

    Ziock, Robert [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Little, Bonnie Colleen [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-02-01

    The Corrective Action Management Unit (CAMU) at Sandia National Laboratories, New Mexico (SNL/NM) consisted of a containment cell, two treatment systems, four associated waste staging and storage areas, and support areas; all were used for management of remediation wastes between 1997 and 2003.

  6. Striking antitumor activity of a methinium system with incorporated quinoxaline unit obtained by spontaneous cyclization.

    Science.gov (United States)

    Bříza, T; Králová, J; Dolenský, B; Rimpelová, S; Kejík, Z; Ruml, T; Hajdúch, M; Džubák, P; Mikula, I; Martásek, P; Poučková, P; Král, V

    2015-03-01

    A novel pentamethinium salt was synthesized with an unforeseen expanded conjugated quinoxaline unit directly incorporated into a pentamethinium chain. The compound exhibited high fluorescence intensity, selective mitochondrial localization, high cytotoxicity, and selectivity toward malignant cell lines, and resulted in remarkable in vivo suppression of tumor growth in mice.

  7. Physical activity, obesity and gastroesophageal reflux disease in the general population

    Institute of Scientific and Technical Information of China (English)

    Therese Dj(a)rv; Anna Wikman; Helena Nordenstedt; Asif Johar; Jesper Lagergren; Pernilla Lagergren

    2012-01-01

    AIM:To clarify the association between physical activity and gastroesophageal reflux disease (GERD) in nonobese and obese people.METHODS:A Swedish population-based cross-sectional survey was conducted.Participants aged 40-79 years were randomly selected from the Swedish Registry of the Total Population.Data on physical activity,GERD,body mass index (BMI) and the covariates age,gender,comorbidity,education,sleeping problems,and tobacco smoking were obtained using validated questionnaires.GERD was self-reported and defined as heartburn or regurgitation at least once weekly,and having at least moderate problems from such symptoms.Frequency of physical activity was categorized into three groups:(1)"high" (several times/week); (2) "intermediate" (approximately once weekly); and (3) "low" (1-3 times/mo or less).Analyses were stratified for participants with "normal weight" (BMI < 25 kg/m2),"overweight" (BMI 25 to ≤ 30 kg/m2) and "obese" (BMI > 30 kg/m2).Multivariate logistic regression was used to calculate odds ratios (ORs) with 95% confidence intervals (CIs),adjusted for potential confounding by covariates.RESULTS:Of 6969 eligible and randomly selected individuals,4910 (70.5%) participated.High frequency of physical activity was reported by 2463 (50%) participants,GERD was identified in 472 (10%) participants,and obesity was found in 680 (14%).There were 226 (5%) individuals with missing information about BMI.Normal weight,overweight and obese participants were similar regarding distribution of gender and tobacco smoking status,while obese participants were on average slightly older,had fewer years of education,more comorbidity,slightly more sleeping problems,lower frequency of physical activity,and higher occurrence of GERD.Among the 2146 normal-weight participants,crude point estimates indicated a decreased risk of GERD among individuals with high frequency of physical activity (OR:0.59,95% CI:0.39-0.89),compared to low frequency of physical

  8. 39 CFR 447.41 - General.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false General. 447.41 Section 447.41 Postal Service UNITED STATES POSTAL SERVICE PERSONNEL RULES OF CONDUCT FOR POSTAL EMPLOYEES Political Activities § 447.41 General. (a) Postal Service employees, except those mentioned in paragraph (b) of this section...

  9. The structure, occurrence and biological activity of ellagitannins: a general review

    Directory of Open Access Journals (Sweden)

    Lidia Lipińska

    2014-09-01

    Full Text Available The present paper deals with the structure, occurrence and biological activity of ellagitannins. Ellagitannins belong to the class of hydrolysable tannins, they are esters of hexahydroxydiphenoic acid and monosaccharide (most commonly glucose. Ellagitannins are slowly hydrolysed in the digestive tract, releasing the ellagic acid molecule. Their chemical structure determines physical and chemical properties and biological activity. Ellagitannins occur naturally in some fruits (pomegranate, strawberry, blackberry, raspberry, nuts (walnuts, almonds, and seeds. They form a diverse group of bioactive polyphenols with anti-infl ammatory, anticancer, antioxidant and antimicrobial (antibacterial, antifungal and antiviral activity. Furthermore, they improve the health of blood vessels. The paper discusses the metabolism and bioavailability of ellagitannins and ellagic acid. Ellagitannins are metabolized in the gastrointestinal tract by intestinal microbiota. They are stable in the stomach and undergo neither hydrolysis to free ellagic acid nor degradation. In turn, ellagic acid can be absorbed in the stomach. This paper shows the role of cancer cell lines in the studies of ellagitannins and ellagic acid metabolism. The biological activity of these compounds is broad and thus the focus is on their antimicrobial, anti-inflammatory and antitumor properties. Ellagitannins exhibit antimicrobial activity against fungi, viruses, and importantly, bacteria, including antibiotic-resistant strains such as methicillinresistant Staphylococcus aureus.

  10. The structure, occurrence and biological activity of ellagitannins: a general review.

    Science.gov (United States)

    Lipińska, Lidia; Klewicka, Elżbieta; Sójka, Michał

    2014-01-01

    The present paper deals with the structure, occurrence and biological activity of ellagitannins. Ellagitannins belong to the class of hydrolysable tannins, they are esters of hexahydroxydiphenoic acid and monosaccharide (most commonly glucose). Ellagitannins are slowly hydrolysed in the digestive tract, releasing the ellagic acid molecule. Their chemical structure determines physical and chemical properties and biological activity. Ellagitannins occur naturally in some fruits (pomegranate, strawberry, blackberry, raspberry), nuts (walnuts, almonds), and seeds. They form a diverse group of bioactive polyphenols with anti-inflammatory, anticancer, antioxidant and antimicrobial (antibacterial, antifungal and antiviral) activity. Furthermore, they improve the health of blood vessels. The paper discusses the metabolism and bioavailability of ellagitannins and ellagic acid. Ellagitannins are metabolized in the gastrointestinal tract by intestinal microbiota. They are stable in the stomach and undergo neither hydrolysis to free ellagic acid nor degradation. In turn, ellagic acid can be absorbed in the stomach. This paper shows the role of cancer cell lines in the studies of ellagitannins and ellagic acid metabolism. The biological activity of these compounds is broad and thus the focus is on their antimicrobial, anti-inflammatory and antitumor properties. Ellagitannins exhibit antimicrobial activity against fungi, viruses, and importantly, bacteria, including antibiotic-resistant strains such as methicillin-resistant Staphylococcus aureus.

  11. Knee complaints seen in general practice: active sport participants versus non-sport participants

    Directory of Open Access Journals (Sweden)

    Koes Bart W

    2008-03-01

    Full Text Available Abstract Background Since knee complaints are common among athletes and are frequently presented in general practice, it is of interest to investigate the type of knee complaints represented in general practice of athletes in comparison with those of non-athletes. Therefore, the aim of this study is to investigate the differences in type of knee complaints between sport participants, in this study defined as athletes, and non-sport participants, defined as non-athletes, presenting in general practice. Further, differences in the initial policy of the GP, medical consumption, and outcome at one-year follow-up were also investigated. Methods Patients consulting their GP for a new episode of knee complaints were invited to participate in this prospective cohort study. From the total HONEUR knee cohort population (n = 1068 we extracted patients who were athletes (n = 421 or non-athletes (n = 388. Results The results showed that acute distortions of the knee were significantly more diagnosed in athletes than in non-athletes (p = 0.04. Further, more athletes were advised by their GP to 'go easy on the knee' than the non-athletes (p Conclusion There are no major differences in the diagnosis and prognosis of knee complaints between athletes and non-athletes presented to the GP. This implies that there are no indications for different treatment strategies applied in both groups. However, athletes are more often advised to 'go easy on the knee' and to rest than non-athletes. Further, there is a trend towards increased medical consumption among athletes while functional disability and pain are lower than among the non-athletes.

  12. A comparative analysis of chiropractic and general practitioner patients in North America: Findings from the joint Canada/United States survey of health, 2002–03

    Directory of Open Access Journals (Sweden)

    Chiang Lu-May

    2006-04-01

    Full Text Available Abstract Background Scientifically rigorous general population-based studies comparing chiropractic with primary-care medical patients within and between countries have not been published. The objective of this study is to compare care seekers of doctors of chiropractic (DCs and general practitioners (GPs in the United States and Canada on a comprehensive set of sociodemographic, quality of life, and health-related variables. Methods Data are from the Joint Canada/U.S. Survey of Health (JCUSH, 2002–03, a random sample of adults in Canada (N = 3505 and the U.S. (N = 5183. Respondents were categorized according to their pattern of health-care use in the past year. Distributions, percentages, and estimates (adjusted odds ratios weighted to reflect the complex survey design were produced. Results Nearly 80% of respondents sought care from GPs; 12% sought DC care. Compared with GP only patients, DC patients in both countries tend to be under 65 and white, with arthritis and disabling back or neck pain. U.S. DC patients are more likely than GP only patients to be obese and to lack a regular doctor; Canadian DC patients are more likely than GP only patients to be college educated, to have higher incomes, and dissatisfied with MD care. Compared with seekers of both GP and DC care, DC only patients in both countries have fewer chronic conditions, take fewer drugs, and have no regular doctor. U.S. DC only patients are more likely than GP+DC patients to be uninsured and dissatisfied with health care; Canadian DC only patients are more likely than GP+DC patients to be under 45, male, less educated, smokers, and not obese, without disabling back or neck pain, on fewer drugs, and lacking a regular doctor. Conclusion Chiropractic and GP patients are dissimilar in both Canada and the U.S., with key differences between countries and between DC patients who do and do not seek care from GPs. Such variation has broad and potentially far-reaching health policy and

  13. Association of proximity and density of parks and objectively measured physical activity in the United States: A systematic review.

    Science.gov (United States)

    Bancroft, Carolyn; Joshi, Spruha; Rundle, Andrew; Hutson, Malo; Chong, Catherine; Weiss, Christopher C; Genkinger, Jeanine; Neckerman, Kathryn; Lovasi, Gina

    2015-08-01

    One strategy for increasing physical activity is to create and enhance access to park space. We assessed the literature on the relationship of parks and objectively measured physical activity in population-based studies in the United States (US) and identified limitations in current built environment and physical activity measurement and reporting. Five English-language scholarly databases were queried using standardized search terms. Abstracts were screened for the following inclusion criteria: 1) published between January 1990 and June 2013; 2) US-based with a sample size greater than 100 individuals; 3) included built environment measures related to parks or trails; and 4) included objectively measured physical activity as an outcome. Following initial screening for inclusion by two independent raters, articles were abstracted into a database. Of 10,949 abstracts screened, 20 articles met the inclusion criteria. Five articles reported a significant positive association between parks and physical activity. Nine studies found no association, and six studies had mixed findings. Our review found that even among studies with objectively measured physical activity, the association between access to parks and physical activity varied between studies, possibly due to heterogeneity of exposure measurement. Self-reported (vs. independently-measured) neighborhood park environment characteristics and smaller (vs. larger) buffer sizes were more predictive of physical activity. We recommend strategies for further research, employing standardized reporting and innovative study designs to better understand the relationship of parks and physical activity.

  14. A New Generalized Discontinuous-PWM Strategy for Active Power Filters

    DEFF Research Database (Denmark)

    Asiminoaei, Lucian; Rodriguez, Pedro; Blaabjerg, Frede

    2007-01-01

    losses in any operating point. This paper proposes a new discontinuous pulse width modulation strategy applied to shunt active power filters. The proposed modulation strategy detects the current vector position relative to the inverter voltage reference and determines instantaneously the optimum clamped...... duration on each phase. It achieves a clamped voltage pattern, with variable lengths depending on the magnitude of the inverter current. This property adaptively reduces the current stress and minimizes the inverter switching losses, regardless of its application. The proposed modulation strategy...... is described, analyzed and validated on a three-phase voltage source inverter, rated at 7 kVA, 400 V, controlled as an active power filter....

  15. Multiobjective optimization in a pseudometric objective space as applied to a general model of business activities

    Science.gov (United States)

    Khachaturov, R. V.

    2016-09-01

    It is shown that finding the equivalence set for solving multiobjective discrete optimization problems is advantageous over finding the set of Pareto optimal decisions. An example of a set of key parameters characterizing the economic efficiency of a commercial firm is proposed, and a mathematical model of its activities is constructed. In contrast to the classical problem of finding the maximum profit for any business, this study deals with a multiobjective optimization problem. A method for solving inverse multiobjective problems in a multidimensional pseudometric space is proposed for finding the best project of firm's activities. The solution of a particular problem of this type is presented.

  16. Evaluation of Prescriptions and Use of Intravenous Pantoprazole in General Wards and Intensive Care Unit of Shahid Sadoughi Hospital in Yazd

    Directory of Open Access Journals (Sweden)

    Seyed-Mojtaba Sohrevardi

    2016-05-01

    Full Text Available Background: Proton pump inhibitors (PPIs are currently the most effective agents for acid related disorders. However, studies show that 25-75% of patients receiving intravenous Pantoprazole had no appropriate justification, indicating high rate of inappropriate prescribing in hospitals. The aim of this study is to examine the appropriate use of intravenous Pantoprazole in accordance with guidelines at Shahid Sadoughi hospital.Methods: From January to April 2015, sample of 100 prescriptions who received Intravenous (IV Pantoprazole were collected with observational and sectional model in Intensive care unit (ICU and general wards of “Shahid Sadoughi” Hospital of Yazd, Iran. Clinical data from patient records are obtained and these data were mapped to establish clinical criteria and appropriate use of Intravenous Pantoprazole.Results: The majority (63% of Intravenous Pantoprazole prescriptions were deemed inappropriate in terms of either indication for use, dose or duration of therapy. 51.5% of the patients were above 55 years old. Endoscopy did not performed in most of the Non UGIB (Non upper gastrointestinal bleeding cases. Most Intravenous Pantoprazole prescriptions were ordered by junior doctors (Intern, and again this group were significantly less likely to prescribe the drug for appropriate reasons when compared with more experienced clinicians.Conclusion: This study suggests that the majority of IV PPI prescriptions in our hospital are inappropriate. Awareness of the result of this article through medical staff could result in more judicious use of intravenous pantoprazole and dose optimization. Physicians and pharmacists can work together to create solutions to inappropriate drug use.

  17. Office of Inspector General audit report on the U.S. Department of Energy`s aircraft activities

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-01-01

    On October 19, 1998, the Office of Inspector General (OIG) was asked to undertake a review of the Department of Energy`s aircraft activities. It was also requested that they report back within 90 days. The OIG has gathered information concerning the number of aircraft, the level of utilization, and the cost of the Department`s aircraft operations. They have also briefly summarized four issues that, in their judgment, may require management attention.

  18. Absence of lateral gastrocnemius activity and differential motor unit behavior in soleus and medial gastrocnemius during standing balance.

    Science.gov (United States)

    Héroux, Martin E; Dakin, Christopher J; Luu, Billy L; Inglis, John Timothy; Blouin, Jean-Sébastien

    2014-01-15

    In a standing position, the vertical projection of the center of mass passes in front of the ankle, which requires active plantar-flexor torque from the triceps surae to maintain balance. We recorded motor unit (MU) activity in the medial (MG) and lateral (LG) gastrocnemius muscle and the soleus (SOL) in standing balance and voluntary isometric contractions to understand the effect of functional requirements and descending drive from different neural sources on motoneuron behavior. Single MU activity was recorded in seven subjects with wire electrodes in the triceps surae. Two 3-min standing balance trials and several ramp-and-hold contractions were performed. Lateral gastrocnemius MU activity was rarely observed in standing. The lowest thresholds for LG MUs in ramp contractions were 20-35 times higher than SOL and MG MUs (P triceps surae motoneurons.

  19. An in vitro method for recording single unit afferent activity from mesenteric nerves innervating isolated segments of rat ileum.

    Science.gov (United States)

    Sharkey, K A; Cervero, F

    1986-04-01

    A technique has been developed for recording single unit afferent activity from mesenteric nerves in isolated segments of rat distal ileum in vitro. The preparation consists of a 3-cm segment of ileum, containing a single neurovascular bundle, held horizontally in an organ bath. One end of the segment is attached to a tension transducer to record changes in longitudinal tension of the gut muscle and the other is connected to a pressure transducer to record changes in intra-luminal pressure. Electromyographic activity of the smooth muscle is recorded using glass-insulated tungsten microelectrodes inserted in the wall of the gut. Afferent nerve activity is recorded with a monopolar platinum wire electrode from filaments of the mesenteric nerves that run between the artery and vein supplying the segment. This preparation permits the detailed analysis of the electrical activity of intestinal afferent nerve fibres correlated with mechanical and chemical events occurring naturally in the gut or imposed experimentally on it.

  20. Intensive care unit admission in patients following rapid response team activation: call factors, patient characteristics and hospital outcomes.

    Science.gov (United States)

    Le Guen, M P; Tobin, A E; Reid, D

    2015-03-01

    Rapid Response Systems (RRSs) have been widely introduced throughout hospital health systems, yet there is limited research on the characteristics and outcomes of patients admitted to an intensive care unit (ICU) following RRS activation. Using database extraction, this study examined the factors associated with ICU admission and patient outcome in patients receiving RRS activation in a tertiary level hospital between 2009 and 2013. Of 3004 RRS activations, 392 resulted in ICU admissions. Call factors associated with ICU admission and increased hospital mortality included tachypnoea (P Medical Emergency Team call triggers breached simultaneously (P admission included young age (P admission and hospital mortality post RRS activation. This information may be useful for risk stratification of deteriorating patients and determination of appropriate escalation.

  1. 15 February 2012 - Geneva United Nations Office Director-General K.-J. Tokayev in the LHC tunnel with Adviser for Relations with international organisations M. Bona and Technology Department Head F. Bordry.

    CERN Multimedia

    Jean-claude Gadmer

    2012-01-01

    Kassym-Jomart Tokayev, director-general of the United Nations Office at Geneva, (centre picture 02), visited CERN on 15 February. He toured the LHC tunnel with Maurizio Bona, CERN’s adviser to the director-general, relations with international organizations, left, and Frédérick Bordry, CERN’s technology department head. He also visited the ATLAS underground experimental area, as well as the exhibition at the Globe of Science and Innovation.

  2. 10 CFR 20.1005 - Units of radioactivity.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Units of radioactivity. 20.1005 Section 20.1005 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION General Provisions § 20.1005 Units of radioactivity. For the purposes of this part, activity is expressed in the special unit...

  3. Dextroamphetamine (but Not Atomoxetine Induces Reanimation from General Anesthesia: Implications for the Roles of Dopamine and Norepinephrine in Active Emergence.

    Directory of Open Access Journals (Sweden)

    Jonathan D Kenny

    Full Text Available Methylphenidate induces reanimation (active emergence from general anesthesia in rodents, and recent evidence suggests that dopaminergic neurotransmission is important in producing this effect. Dextroamphetamine causes the direct release of dopamine and norepinephrine, whereas atomoxetine is a selective reuptake inhibitor for norepinephrine. Like methylphenidate, both drugs are prescribed to treat Attention Deficit Hyperactivity Disorder. In this study, we tested the efficacy of dextroamphetamine and atomoxetine for inducing reanimation from general anesthesia in rats. Emergence from general anesthesia was defined by return of righting. During continuous sevoflurane anesthesia, dextroamphetamine dose-dependently induced behavioral arousal and restored righting, but atomoxetine did not (n = 6 each. When the D1 dopamine receptor antagonist SCH-23390 was administered prior to dextroamphetamine under the same conditions, righting was not restored (n = 6. After a single dose of propofol (8 mg/kg i.v., the mean emergence times for rats that received normal saline (vehicle and dextroamphetamine (1 mg/kg i.v. were 641 sec and 404 sec, respectively (n = 8 each. The difference was statistically significant. Although atomoxetine reduced mean emergence time to 566 sec (n = 8, this decrease was not statistically significant. Spectral analysis of electroencephalogram recordings revealed that dextroamphetamine and atomoxetine both induced a shift in peak power from δ (0.1-4 Hz to θ (4-8 Hz during continuous sevoflurane general anesthesia, which was not observed when animals were pre-treated with SCH-23390. In summary, dextroamphetamine induces reanimation from general anesthesia in rodents, but atomoxetine does not induce an arousal response under the same experimental conditions. This supports the hypothesis that dopaminergic stimulation during general anesthesia produces a robust behavioral arousal response. In contrast, selective noradrenergic stimulation

  4. Using the Activity Model of Inquiry to Enhance General Chemistry Students' Understanding of Nature of Science

    Science.gov (United States)

    Marchlewicz, Sara C.; Wink, Donald J.

    2011-01-01

    Nature of science refers to the processes of scientific activity and the social and cultural premises involved in the creation of scientific knowledge. Having an informed view of nature of science is important in the development of scientifically literate citizens. However, students often come to the classroom with misconceptions about nature of…

  5. Seeking the General Explanation: A Test of Inductive Activities for Learning and Transfer

    Science.gov (United States)

    Shemwell, Jonathan T.; Chase, Catherine C.; Schwartz, Daniel L.

    2015-01-01

    Evaluating the relation between evidence and theory should be a central activity for science learners. Evaluation comprises both hypothetico-deductive analysis, where theory precedes evidence, and inductive synthesis, where theory emerges from evidence. There is mounting evidence that induction is an especially good way to help learners grasp the…

  6. Using the Activity Model of Inquiry to Enhance General Chemistry Students' Understanding of Nature of Science

    Science.gov (United States)

    Marchlewicz, Sara C.; Wink, Donald J.

    2011-01-01

    Nature of science refers to the processes of scientific activity and the social and cultural premises involved in the creation of scientific knowledge. Having an informed view of nature of science is important in the development of scientifically literate citizens. However, students often come to the classroom with misconceptions about nature of…

  7. Utilizing Generalization Tactics to Promote Leisure-Time Physical Activity for Students with Intellectual Disabilities

    Science.gov (United States)

    Haegele, Justin A.; Park, Seung Yeon

    2016-01-01

    Research suggests that school-aged individuals with intellectual disabilities (ID) tend to be less physically active than their typically developing peers (e.g., Shields, King, Corbett, & Imms, 2014). While these students can be successful in acquiring motor and sport-related skills during physical education, they tend not to use those skills…

  8. Periodic Modulation of Motor-Unit Activity in Extrinsic Hand Muscles During Multidigit Grasping

    Science.gov (United States)

    Johnston, Jamie A.; Winges, Sara A.; Santello, Marco

    2007-01-01

    We recently examined the extent to which motor units of digit flexor muscles receive common input during multidigit grasping. This task elicited moderate to strong motor-unit synchrony (common input strength, CIS) across muscles (flexor digitorum profundus, FDP, and flexor pollicis longus, FPL) and across FDP muscle compartments, although the strength of this common input was not uniform across digit pairs. To further characterize the neural mechanisms underlying the control of multidigit grasping, we analyzed the relationship between firing of single motor units from these hand muscles in the frequency domain by computing coherence. We report three primary findings. First, in contrast to what has been reported in intrinsic hand muscles, motor units belonging to different muscles and muscle compartments of extrinsic digit flexors exhibited significant coherence in the 0- to 5- and 5- to 10-Hz frequency ranges and much weaker coherence in the higher 10–20 Hz range (maximum 0.0025 and 0.0008, respectively, pooled across all FDP compartment pairs). Second, the strength and incidence of coherence differed considerably across digit pairs. Third, contrary to what has been reported in the literature, across-muscle coherence can be stronger and more prevalent than within-muscle coherence, as FPL–FDP2 (thumb-index digit pair) exhibited the strongest and most prevalent coherence in our data (0.010 and 43% at 3 Hz, respectively). The heterogeneous organization of common input to these muscles and muscle compartments is discussed in relation to the functional role of individual digit pairs in the coordination of multiple digit forces in grasping. PMID:15744006

  9. Synthesis of marine ecosystem monitoring activities for the United States Virgin Islands: 1990-2009

    OpenAIRE

    2012-01-01

    The ecological integrity of coral reef ecosystems in the U.S. Caribbean is widely considered to have deteriorated in the last three decades due to a range of threats and stressors from both human and non-human processes Rothenberger 2008, Wilkinson 2008). In response to the threats to Caribbean coral reef ecosystems and other regions around the world, the United States Government authorized the Coral Reef Conservation Act of 2000 to: (1) preserve, sustain, and restore the condition of coral r...

  10. Determination of the fate of alcohol ethoxylate homologues in a laboratory continuous activated-sludge unit study.

    Science.gov (United States)

    Wind, T; Stephenson, R J; Eadsforth, C V; Sherren, A; Toy, R

    2006-05-01

    Environmental monitoring indicates that the distribution of alcohol ethoxylate (AE) homologues in wastewater treatment plant (WWTP) effluents differs from the distribution in commercial AE products, with a relative higher proportion of fatty alcohol (AOH, which is AE with zero ethoxylation). To determine the contribution of AE-derived AOH to the total concentration of AE and AOH in WWTP effluents, we conducted a laboratory continuous activated-sludge study (CAS). This consisted of a test unit fed with AE-amended synthetic sewage and a control unit fed with only synthetic sewage to avoid AE contamination from the feed. The removal efficiencies of some 114 AE homologues were determined by the application of a specific and sensitive analytical method. The extent of the removal of AE ranged from 99.70% for C18 compounds to > 99.98% for C12-16. Relatively high-AOH concentrations were observed in the effluents from blank and test units. By building the concentration difference from the test minus the control unit, the AE in the CAS effluent originating from AE in the influent was determined. Thus, it could be shown that AOH represented only 19% of the total AE (EO0-18) in the CAS, while monitoring in 29 WWTP effluents (European, Canadian, and US) revealed in total a mean AOH fraction of 55% (5-82%) of the total AE (EO0-18). This shows that only a small fraction of AOH in WWTP effluents originates from AE entering the WWTP.

  11. Prevalence of Physical Activity in the United States: Behavioral Risk Factor Surveillance System, 2001

    Directory of Open Access Journals (Sweden)

    Barbara E. Ainsworth, PhD, MPH

    2005-03-01

    Full Text Available Introduction The health benefits of regular cardiovascular exercise are well-known. Such exercise, however, has traditionally been defined as vigorous physical activity, such as jogging, swimming, or aerobic dance. Exercise of moderate intensity also promotes health, and many U.S. adults may be experiencing the health benefits of exercise through lifestyle activities of moderate intensity, such as yard work, housework, or walking for transportation. Until recently, public health surveillance systems have not included assessments of this type of physical activity, focusing on exercise of vigorous intensity. We used an enhanced surveillance tool to describe the prevalence and amount of both moderate-intensity and vigorous-intensity physical activity among U.S. adults. Methods We analyzed data from the 2001 Behavioral Risk Factor Surveillance System, a state-based, random-digit–dialed telephone survey administered to U.S. adults aged 18 years and older (n = 82,834 men and 120,286 women. Physical activity behavior was assessed using questions designed to quantify the frequency of participation in moderate- or vigorous-intensity physical activities performed during leisure time or for household chores and transportation. Results Overall, 45% of adults (48% of men and 43% of women were active at recommended levels during nonworking hours (at least 30 minutes five or more days per week in moderate-intensity activities, equivalent to brisk walking, or at least 20 minutes three or more days per week in vigorous activities, equivalent to running, heavy yard work, or aerobic dance. Less than 16% of adults (15% of men and 17% of women reported no moderate or vigorous activity in a usual week. Conclusion Integrating surveillance of lifestyle activities into national systems is possible, and doing so may provide a more accurate representation of the prevalence of recommended levels of physical activity. These results, however, suggest that the majority of U

  12. Photocaged Competitor Guests: A General Approach Toward Light-Activated Cargo Release From Cucurbiturils.

    Science.gov (United States)

    Romero, Miguel A; Basílio, Nuno; Moro, Artur J; Domingues, Mara; González-Delgado, José A; Arteaga, Jesús F; Pischel, Uwe

    2017-07-03

    A general approach toward the light-induced guest release from cucurbit[7]uril by means of a photoactivatable competitor was devised. An o-nitrobenzyl-caged competitor is photolyzed to generate a competitive guest that can displace cargo from the host macrocycle solely based on considerations of chemical equilibrium. With this method the release of terpene guests from inclusion complexes with cucurbit[7]uril was demonstrated. The binding of the herein investigated terpenes, all being lead fragrant components in essential oils, has been characterized for the first time. They feature binding constants of up to 10(8)  L mol(-1) and a high differential binding selectivity (spanning four orders of magnitude for the binding constants for the particular set of terpenes). By fine-tuning the photoactivatable competitor guest, selective and also sequential release of the terpenes was achieved. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. Leisure-time physical activity among older adults. United States, 1990.

    Science.gov (United States)

    Yusuf, H R; Croft, J B; Giles, W H; Anda, R F; Casper, M L; Caspersen, C J; Jones, D A

    1996-06-24

    To investigate the prevalence and selected correlates of leisure-time physical activity in a nationally representative sample of persons aged 65 years or older. Data from 2783 older male and 5018 older female respondents to the 1990 National Health Interview Survey were used. Regular physical activity was defined as participation in leisure-time physical activities 3 times or more per week for 30 minutes or more during the previous 2 weeks. Odds ratios (ORs) were estimated from multivariate logistic regression analysis. Prevalence of regular physical activity was 37% among older men and 24% among older women. Correlates of regular physical activity included the perception of excellent to good health (men: OR, 1.5; 95% confidence interval [CI], 1.1-1.9; women: OR, 1.6; 95% CI, 1.3-1.9), correct exercise knowledge (men: OR, 2.4; 95% CI, 1.9-3.1; women: OR, 2.7; 95% CI, 2.2-3.4), no activity limitations (men: OR, 1.3; 95% CI, 1.0-1.6; women: OR, 1.7; 95% CI, 1.4-2.0) and not perceiving "a lot" of stress during the previous 2 weeks (men: OR, 1.7; 95% CI, 1.2-2.4; women: OR, 1.3; 95% CI, 1.0-1.6). Among those who had been told at least twice that they had high blood pressure, physician's advice to exercise was associated with regular physical activity (men: OR, 1.6; 95% CI, 1.2-2.3; women: OR, 1.5; 95% CI, 1.2-1.9). The 2 major activities among active older adults were walking (men, 69%; women, 75%) and gardening (men, 45%; women, 35%). Prevalence of regular physical activity is low among older Americans. Identifying the correlates of physical activity will help to formulate strategies to increase physical activity in this age group.

  14. [Effects of automobile lead on the general growth and sexual activity of the rat].

    Science.gov (United States)

    el Feki, A; Ghorbel, F; Smaoui, M; Makni-Ayadi, F; Kammoun, A

    2000-01-01

    To identify the active element of automotive exhaust gas responsible for masculine infertility, previously proved by our laboratory, we undertook these experiments. Four hundred young male and female rats were exposed during two months (30 min/d) to three types of automotive exhaust gases. The first type emanated from an engine running on gasoline with lead, the second from an unleaded gasoline engine, the third from a diesel engine. These three engines had the same power (5 horsepower vehicles gas also induced in male rats the atrophy of the testicle, seminal vesicle and epididym, certain pathological changes in spermatogenesis shown by the histologic study, and a decrease of the serum's testosterone level. In female rats, the relative weights of the ovary and uterus, as well as the percentage of the arrival of oestrus, were not affected by the gaseous treatment. Both the second and third types of gases seemed less active on the masculine sex as far as these parameters are concerned. Our study suggests that, for light vehicles, leaded gasoline pollutes more than unleaded gasoline or diesel fuels, and that the lead present only in the first type would be the active element responsible for the masculine infertility and body weight gain reduction in rats.

  15. Activation and inactivation of thyroid hormone by deiodinases: local action with general consequences.

    Science.gov (United States)

    Gereben, B; Zeöld, A; Dentice, M; Salvatore, D; Bianco, A C

    2008-02-01

    The thyroid hormone plays a fundamental role in the development, growth, and metabolic homeostasis in all vertebrates by affecting the expression of different sets of genes. A group of thioredoxin fold-containing selenoproteins known as deiodinases control thyroid hormone action by activating or inactivating the precursor molecule thyroxine that is secreted by the thyroid gland. These pathways ensure regulation of the availability of the biologically active molecule T3, which occurs in a time-and tissue-specific fashion. In addition, because cells and plasma are in equilibrium and deiodination affects central thyroid hormone regulation, these local deiodinase-mediated events can also affect systemic thyroid hormone economy, such as in the case of non-thyroidal illness. Heightened interest in the field has been generated following the discovery that the deiodinases can be a component in both the Sonic hedgehog signaling pathway and the TGR-5 signaling cascade, a G-protein-coupled receptor for bile acids. These new mechanisms involved in deiodinase regulation indicate that local thyroid hormone activation and inactivation play a much broader role than previously thought.

  16. Investigation of tunable LED lighting for general illumination employing preliminary activity recognition sensor network

    Science.gov (United States)

    Thompson, Maria; Spaulding, Jeremy; Larson, Kent; Hall, Harrison

    2011-10-01

    Digitally controlled solid state lighting systems can afford a range of different qualities of light, adjustable to users' requirements. Sensor networks allow lighting changes to be actuated in response to the location, activities, and paths of the occupants. This paper reports initial results of an ongoing research to explore strategic control of a tunable LED system, in response to a preliminary activity recognition platform, as well as the associated human factors. Tunable LED panels connected to a sensor network were installed to illuminate three distinct occupied spaces: a private office, a public office space and a corridor at MIT Media Lab. Human factors experiments were conducted to assess visual acceptability under changing lighting conditions. In the first phase variations in color rendering were applied to verify perception of subtle changes in white lighting. Results from this phase indicate that it is possible to correlate activities with sensitivity to spectral change. In the second phase the question is how colored light can be used for energy savings and as a communication medium in these commercial spaces.

  17. Contemporary antimicrobial activity of triple antibiotic ointment: a multiphased study of recent clinical isolates in the United States and Australia.

    Science.gov (United States)

    Jones, Ronald N; Li, Qing; Kohut, Bruce; Biedenbach, Douglas J; Bell, Jan; Turnidge, John D

    2006-01-01

    Triple antibiotic ointment (TAO) containing neomycin, polymyxin B, and bacitracin was launched in the 1950s in the United States (USA) as a prescription product and then was used over the counter (OTC) since the 1970s (USA) to prevent superficial wound infections. In Australia, TAO has been restricted to prescription use. This study 1) determined cross-resistance patterns of neomycin compared with other aminoglycosides; 2) determined the level and trend of resistance to TAO and individual components especially versus mupirocin-resistant strains (USA); and 3) established the baseline TAO activity level against pathogens from Australia. A total of 200 strains (> or =50% gentamicin-resistant) from the United States were used for the cross-resistance study including Staphylococcus aureus (110), coagulase-negative staphylococci (CoNS; 50), Pseudomonas aeruginosa (10), Escherichia coli (20), and other Enterobacteriaceae (10) tested against TAO, bacitracin, polymyxin B, neomycin, amikacin, gentamicin, streptomycin, tobramycin, and mupirocin. Fifty gentamicin-resistant isolates from each year (1997-2002) were used to determine the activity of TAO over time. Baseline resistance rates of TAO among 300 Australian isolates (AGARS Program, 2002-2003) were also studied. Reference broth microdilution methods were used in all phases of this study. At a 1:100 dilution of the ointment concentration, TAO inhibited all CoNS, Pseudomonas aeruginosa, and Enterobacteriaceae isolates, and resistance to TAO among Staphylococcus aureus at this concentration was only 5% in the cross-resistance study. Patterns of susceptibility in the United States did not significantly vary from 1997 to 2002. Australian pathogens showed that TAO was 98% active against methicillin-resistant Staphylococcus aureus and 100% for Enterobacteriaceae, methicillin-susceptible S. aureus, CoNS, and P. aeruginosa, the rates equivalent to those observed in the United States. Mupirocin-resistant S. aureus (5%) and Co

  18. 31 August 2008 - Secretary General of the United Nations Ban Ki-moon visiting CMS experimental underground area and LHC tunnel with CERN Director-General R. Aymar and Collaboration Spokesperson T. Virdee. Director-General of the United Nations Office at Geneva S. Ordzhonikidze also present.

    CERN Document Server

    Maximilien Brice

    2008-01-01

    Also present on the photographs: Guests: Representative of the French Republic O. Laurens-Bernard, Sous Préfet de Gex Deputy Permanent representative C. Guilhou, Permanent Mission of France to the UN CERN: CMS Collaboration Technical Coordinator A. Ball Chief Scientific Officer, Deputy Director-General J. Engelen Group Leader in matter of Safety C. Schaefer LHC engineer in charge L. Ponce

  19. Use of Microcomputers in Air Weather Service Units for Administrative, Managerial and Technical Activities

    Science.gov (United States)

    1984-04-01

    20 Softwre ............................................... 62 Officem Auomaiontins the.Busiess.Worl...but professional and managerial staff as well1 ... (9:2) The General Services Administration was even more specific when * it defined office automation...Conquests for the Computer," Nation’s Business, Vol. 70, No. 6 (June 1982): pp. 67-76. Spindle, Les. "Computerizing Your Office," Radio -Electronics, Vol

  20. Muscle-Strengthening Activities and Participation among Adults in the United States

    Science.gov (United States)

    Loustalot, Fleetwood; Carlson, Susan A.; Kruger, Judy; Buchner, David M.; Fulton, Janet E.

    2013-01-01

    Purpose: To describe those who reported meeting the "2008 Physical Activity Guidelines for Americans" ("2008 Guidelines") muscle-strengthening standard of 2 or more days per week, including all seven muscle groups, and to assess the type and location of muscle-strengthening activities performed. Method: Data from HealthStyles…