WorldWideScience

Sample records for unirradiated cartridges self-nucleate

  1. IBM 3480 tape cartridge

    CERN Multimedia

    1984-01-01

    The 3480 tape format is a magnetic tape data storage format developed by IBM. The cartridge contains a single reel. IBM’s 3480 cartridge tape system sought to replace the traditional reels of magnetic tape in the computer center. Because of their speed, reliability, durability and low media cost, these tapes and tape drives are still in high demand. A hallmark of the genre is transferability. Tapes recorded with one tape drive are generally readable on another drive, even if the tape drives were built by different manufacturers.

  2. Transport insurance of unirradiated nuclear fuels

    International Nuclear Information System (INIS)

    Matto, H.

    1985-01-01

    Special conditions must be taken into account in transport insurance for nuclear materials even if the nuclear risk involved is negligible, as in shipments of unirradiated nuclear fuels. The shipwreck of the 'Mont Louis' has raised a number of open points which must be solved pragmatically within the framework of transport insurance. Some proposals are outlined in the article. (orig.) [de

  3. The Indicating FTA Elute Cartridge

    Science.gov (United States)

    de Bie, Roosmarie P.; Schmeink, Channa E.; Bakkers, Judith M.J.E.; Snijders, Peter J.F.; Quint, Wim G.V.; Massuger, Leon F.A.G.; Bekkers, Ruud L.M.; Melchers, Willem J.G.

    2011-01-01

    The clinically validated high-risk human papillomavirus (hrHPV) Hybrid Capture 2 (HC2) and GP5+/6+-PCR assays were analyzed on an Indicating FTA Elute cartridge (FTA cartridge). The FTA cartridge is a solid dry carrier that allows safe transport of cervical samples. FTA cartridge samples were compared with liquid-based samples for hrHPV and high-grade cervical intraepithelial neoplasia (CIN) detection. One cervical sample was collected in a liquid-based medium, and one was applied to the FTA cartridge. DNA was eluted directly from the FTA cartridge by a simple elution step. HC2 and GP5+/6+-PCR assays were performed on both the liquid-based and the FTA-eluted DNA of 88 women. Overall agreement between FTA and liquid-based samples for the presence of hrHPV was 90.9% with GP5+/6+-PCR and 77.3% with HC2. The sensitivity for high-grade CIN of hrHPV testing on the FTA cartridges was 84.6% with GP5+/6+-PCR and only 53.8% with HC2. By comparison, these sensitivities on liquid-based samples were 92.3% and 100% for GP5+/6+-PCR and HC2, respectively. Therefore, the FTA cartridge shows reasonably good overall agreement for hrHPV detection with liquid-based media when using GP5+/6+-PCR but not HC2 testing. Even with GP5+/6+-PCR, the FTA cartridge is not yet capable of detecting all high-grade CIN lesions. PMID:21704269

  4. Thermal analysis with expendable cartridge

    International Nuclear Information System (INIS)

    Susaki, K.; Landgraf, F.J.G.

    1981-01-01

    The pratical method of thermal analysis with expendable cartridge and some aspects of its use are presented. The results of the method applied to the system Nb-Mn are presented together with data from microprobe. (Author) [pt

  5. Stress corrosion crack growth in unirradiated zircaloy

    International Nuclear Information System (INIS)

    Pettersson, K.

    1978-10-01

    Experimental techniques suitable for the determination of stress corrosion crack growth rates in irradiated Zircaloy tube have been developed. The techniques have been tested on unirradiated. Zircaloy and it was found that the results were in good agreement with the results of other investigations. Some of the results were obtained at very low stress intensities and the crack growth rates observed, gave no indication of the existance of a K sub(ISCC) for iodine induced stress corrosion cracking in Zircaloy. This is of importance both for fuel rod behavior after a power ramp and for long term storage of spent Zircaloy-clad fuel. (author)

  6. The Imation 9840 Tape Cartridge

    CERN Multimedia

    It’s a 20 GB uncompressed center-load cartridge used in StorageTek T9840 tape drives. The tape is a Metal Particle (MP) tape suitable for use on all Oracle/Sun/StorageTek 9840 A, B, C and D drives. The 9840 tape has an archival life of 15-30 years.

  7. Quick-change filter cartridge

    Science.gov (United States)

    Rodgers, John C.; McFarland, Andrew R.; Ortiz, Carlos A.

    1995-01-01

    A quick-change filter cartridge. In sampling systems for measurement of airborne materials, a filter element is introduced into the sampled airstream such that the aerosol constituents are removed and deposited on the filter. Fragile sampling media often require support in order to prevent rupture during sampling, and careful mounting and sealing to prevent misalignment, tearing, or creasing which would allow the sampled air to bypass the filter. Additionally, handling of filter elements may introduce cross-contamination or exposure of operators to toxic materials. Moreover, it is desirable to enable the preloading of filter media into quick-change cartridges in clean laboratory environments, thereby simplifying and expediting the filter-changing process in the field. The quick-change filter cartridge of the present invention permits the application of a variety of filter media in many types of instruments and may also be used in automated systems. The cartridge includes a base through which a vacuum can be applied to draw air through the filter medium which is located on a porous filter support and held there by means of a cap which forms an airtight seal with the base. The base is also adapted for receiving absorbing media so that both particulates and gas-phase samples may be trapped for investigation, the latter downstream of the aerosol filter.

  8. Unirradiated cladding rip-propagation tests

    International Nuclear Information System (INIS)

    Hu, W.L.; Hunter, C.W.

    1981-04-01

    The size of cladding rips which develop when a fuel pin fails can affect the subassembly cooling and determine how rapidly fuel escapes from the pin. The object of the Cladding Rip Propagation Test (CRPT) was to quantify the failure development of cladding so that a more realistic fuel pin failure modeling may be performed. The test results for unirradiated 20% CS 316 stainless steel cladding show significantly different rip propagation behavior at different temperatures. At room temperature, the rip growth is stable as the rip extension increases monotonically with the applied deformation. At 500 0 C, the rip propagation becomes unstable after a short period of stable rip propagation. The rapid propagation rate is approximately 200 m/s, and the critical rip length is 9 mm. At test temperatures above 850 0 C, the cladding exhibits very high failure resistances, and failure occurs by multiple cracking at high cladding deformation. 13 figures

  9. Dissolution experiments of unirradiated uranium dioxide pellets

    International Nuclear Information System (INIS)

    Ollila, K.

    1985-01-01

    The purpose of this study was to measure the dissolution rate of uranium from unirradiated uranium dioxide pellets in deionized water and natural groundwater. Moreover, the solubility limit of uranium in natural groundwater was measured. Two different temperatures, 25 and 60 deg C were used. The low oxygen content of deep groundwater was simulated. The dissolution rate of uranium varied from 10 -7 to 10 -8 g cm -2 d -1 . The rate in reionized water was one order of magnitude lower than in groundwater. No great difference was observed between the natural groundwaters with different composition. Temperature seems to have effect on the dissolution rate. The solubility limit of uranium in natural groundwater in reducing conditions, at 25 deg C, varied from 20 to 600 μg/l and in oxidizing conditions, at 60 deg C, from 4 to 17 mg/l

  10. Truck accident involving unirradiated nuclear fuel

    International Nuclear Information System (INIS)

    Carlson, R.W.; Fischer, L.E.

    1993-01-01

    In the early morning of Dec. 16, 1991, a severe accident occurred when a passenger vehicle traveling in the wrong direction collided with a tractor trailer carrying 24 unirradiated nuclear fuel assemblies in 12 containers on Interstate I-91 in Springfield, Massachusetts. This paper documents the mechanical circumstances of the accident and assesses the physical environment to which the containers were exposed and the response of the containers and their contents. The accident involved four impacts where the truck was struck by the car, impacted on the center guardrail, impacted on the outer concrete barrier and came to rest against the center guardrail. The impacts were followed by a fire that began in the engine compartment, spread to the tractor and cab, and eventually spread to the trailer and payload. The fire lasted for about three hours and the packages were involved in the fire for about two hours. As a result of the fire, the tractor-trailer was completely destroyed and the packages were exposed to flames with temperatures between 1,300 F and 1,800 F. The fuel assemblies remained intact during the accident and there was no release of any radioactive material during the accident. This was a very severe accident; however, the injuries were minor and at no time was the public health and safety at risk

  11. StorageTek T10000 Data Cartridge

    CERN Multimedia

    This data cartridge works on several StorageTek systems. The goal is to provide cartridge compatibility across several system. It has been designed for space saving and ultra-high capacity tape. It permit to fulfill high-volume backup, archiving, and disaster recovery.

  12. StorageTek T10000 Tape Cartridge

    CERN Multimedia

    1985-01-01

    Oracle StorageTek T10000T2 cartridge has total capacity of 5 TB. It is actually manufactured by Fuji Film, uses Barium Ferrite (BaFe) particles technology data store, but is also equipped with RFID chip. There is over 1 km of tape inside of the cartridge with 3584 data tracks and it supports over 25000 load/unload cycles. The archival life is estimated to be around 30 years and uncorrected bit error rate is 10-19. CERN however usually migrates data to newer technologies roughly every 5 years in order to keep the footprint under control.

  13. The reactor Phenix - cartridge rupture detection

    International Nuclear Information System (INIS)

    Graftieaux, J.

    1967-01-01

    This report defines the role of cartridge rupture detection in the reactor Phenix. It gives the possible methods, their probable performances, their advantages and disadvantages. The final form of the installation will be determined mainly by the degree of safety required, by the technical possibilities of the reactor design and by the operational flexibility wanted. (author) [fr

  14. CONSTRUCTION AND OPTIMISATION OF A CARTRIDGE FILTER ...

    African Journals Online (AJOL)

    a

    1Department of Chemistry, Egerton University, P.O. Box 356, Njoro, Kenya .... the resident time in the filter, thus there is not enough time for F- to interact with the ... associated with creation of too much backpressure in the cartridge as well as ...

  15. Rescue Effects: Irradiated Cells Helped by Unirradiated Bystander Cells

    Science.gov (United States)

    Lam, R. K. K.; Fung, Y. K.; Han, W.; Yu, K. N.

    2015-01-01

    The rescue effect describes the phenomenon where irradiated cells or organisms derive benefits from the feedback signals sent from the bystander unirradiated cells or organisms. An example of the benefit is the mitigation of radiation-induced DNA damages in the irradiated cells. The rescue effect can compromise the efficacy of radioimmunotherapy (RIT) (and actually all radiotherapy). In this paper, the discovery and subsequent confirmation studies on the rescue effect were reviewed. The mechanisms and the chemical messengers responsible for the rescue effect studied to date were summarized. The rescue effect between irradiated and bystander unirradiated zebrafish embryos in vivo sharing the same medium was also described. In the discussion section, the mechanism proposed for the rescue effect involving activation of the nuclear factor κB (NF-κB) pathway was scrutinized. This mechanism could explain the promotion of cellular survival and correct repair of DNA damage, dependence on cyclic adenosine monophosphate (cAMP) and modulation of intracellular reactive oxygen species (ROS) level in irradiated cells. Exploitation of the NF-κB pathway to improve the effectiveness of RIT was proposed. Finally, the possibility of using zebrafish embryos as the model to study the efficacy of RIT in treating solid tumors was also discussed. PMID:25625514

  16. Scintillation activity in an unirradiated single crystal of 3-hydroxyxanthine

    International Nuclear Information System (INIS)

    Cooke, D.W.; Jahan, M.S.; Alexander, C. Jr.

    1976-01-01

    A method of growing single crystals (approximately 4mm long) of 3-hydroxyxanthine is described. Observed scintillations occurring in an unirradiated single crystal of this potent oncogen as the temperature is lowered from 300 to 90 K are shown. It was found that these scintillations occur upon heating or cooling and do not diminish in activity as the number of heating and cooling cycles increase. It was found that a short duration u.v. exposure would terminate the scintillation activity and various attempts (such as annealing and pressure changes) to rejuvenate them were unsuccessful. With these observations in mind speculation is made concerning the mechanisms associated with the production of purine N-oxide derivatives. (U.K.)

  17. Characterization of un-irradiated and irradiated reactor graphite; Karakterizacija neozracenog i ozracenog reaktorskog grafita

    Energy Technology Data Exchange (ETDEWEB)

    Marinkovic, S [Institute of Nuclear Sciences Boris Kidric, Vinca, Beograd (Yugoslavia)

    1965-11-15

    This report contains three parts: characterization of Yugoslav nuclear graphite development of methods and obtained results, characterization of un-irradiated and irradiated domestic nuclear graphite; calculation of electrical conductivity changes due to vacancies in the graphite crystal lattice.

  18. Criticality safety evaluation report for K Basin filter cartridges

    International Nuclear Information System (INIS)

    Schwinkendorf, K.N.

    1995-01-01

    A criticality safety evaluation of the K Basin filter cartridge assemblies has been completed to support operations without a criticality alarm system. The results show that for normal operation, the filter cartridge assembly is far below the safety limit of k eff = 0.95, which is applied to plutonium systems at the Hanford Site. During normal operating conditions, uranium, plutonium, and fission and corrosion products in solution are continually accumulating in the available void spaces inside the filter cartridge medium. Currently, filter cartridge assemblies are scheduled to be replaced at six month intervals in KE Basin, and at one year intervals in KW Basin. According to available plutonium concentration data for KE Basin and data for the U/Pu ratio, it will take many times the six-month replacement time for sufficient fissionable material accumulation to take place to exceed the safety limit of k eff = 0.95, especially given the conservative assumption that the presence of fission and corrosion products is ignored. Accumulation of sludge with a composition typical of that measured in the sand filter backwash pit will not lead to a k eff = 0.95 value. For off-normal scenarios, it would require at least two unlikely, independent, and concurrent events to take place before the k eff = 0.95 limit was exceeded. Contingencies considered include failure to replace the filter cartridge assemblies at the scheduled time resulting in additional buildup of fissionable material, the loss of geometry control from the filter cartridge assembly breaking apart and releasing the individual filter cartridges into an optimal configuration, and concentrations of plutonium at U/Pu ratios less than measured data for KE Basin, typically close to 400 according to extensive measurements in the sand filter backwash pit and plutonium production information

  19. Detection of irradiated spice in blend of irradiated and un-irradiated spices using thermoluminescence method

    International Nuclear Information System (INIS)

    Goto, Michiko; Yamazaki, Masao; Sekiguchi, Masayuki; Todoriki, Setsuko; Miyahara, Makoto

    2007-01-01

    Five blended spice sample were prepared by mixing irradiated and un-irradiated black pepper and paprika at different ratios. Blended black pepper containing 2%(w/w) of 5.4 kGy-irradiated black pepper showed no maximum at glow1. Irradiated black pepper samples, mixed to 5 or 10%(w/w), were identified as 'irradiated' or 'partially irradiated' or 'un-irradiated'. All samples with un-irradiated pepper up to 20%(w/w) were identified as irradiated'. In the case 5.0 kGy-irradiated paprika were mixed with un-irradiated paprika up to 5%(w/w), all samples were identified as irradiated'. The glow1 curves of samples, including irradiated paprika at 0.2%(w/w) or higher, exhibited a maximum between 150 and 250degC. The results suggest the existence of different critical mixing ratio for the detection of irradiation among each spices. Temperature range for integration of the TL glow intensity were compared between 70-400degC and approximate 150-250degC, and revealed that the latter temperature range was determined based on the measurement of TLD100. Although TL glow ratio in 150-250degC was lower than that of 70-400degC range, identification of irradiation was not affected. Treatment of un-irradiated black pepper and paprika with ultraviolet rays had no effect on the detection of irradiation. (author)

  20. Temperature dependence of magnetoresistance in neutron-irradiated and unirradiated high resistivity p-type silicon

    International Nuclear Information System (INIS)

    Yildirim, M.; Efeoglu, H.; Abay, B.; Yogurtcu, Y.K.

    1996-01-01

    The temperature dependence of the transverse magnetoresistance in irradiated and unirradiated p-type Si is studied in the range from 120 to 290 K. The magnetoresistance coefficients for the unirradiated left angle 001 right angle and left angle 1 anti 10 right angle samples increases with decreasing sample temperature in the range from 160 to 290 K, however, this behavior is reversed below 160 K. It is proposed that this reversal is due to the double injection effect. The magnetoresistance coefficient for the irradiated left angle 001 right angle sample increases with decreasing sample temperature in the range of 120 to 290 K and is greater than that for the unirradiated left angle 001 right angle sample. This result can be explained by increased scattering due to the increased number of defects produced by irradiation. On the other hand, the magnetoresistance coefficient for the unirradiated left angle 1 anti 10 right angle sample is found to be greater than that of the unirradiated left angle 001 right angle sample. (orig.)

  1. Adsorbent cartridge for the exhaust of diazo process machines

    International Nuclear Information System (INIS)

    Michlin, N.; Thies, E.J.

    1982-01-01

    A disposable cartridge filled with a chemical composition that acts as an adsorbent for ammonia vapor is adapted to be used in connection with a diazo process printing machine having a vacuum exhausted chamber. Exhaust from the chamber is passed through the cartridge to remove the noxious ammonia vapors and then is vented into the atmosphere. The cartridge is housed in an elongated rectangular cardboard box having three end flaps formed at each of its opposed open ends. Two opposed flaps of each set are formed with central holes and a plastic screen section adhered between these flaps to retain and allow access to the center section of the box which contains the adsorbent chemical. The center end flaps have knock-outs or tear strips that allow holes to be formed in their centers. These center end flaps cover the screens during shipment and when the cartridge is ready for use the center sections of these end flaps are knocked-out to allow the machine exhaust to be vented into and out of the cartridge

  2. Functional recovery in the irradiated kidney following removal of the contralateral unirradiated kidney

    International Nuclear Information System (INIS)

    Robbins, M.E.C.; Hopewell, J.W.; Golding, S.J.

    1986-01-01

    Radiation-induced damage to one kidney in the pig causes a fall in total renal function; this would be recognised and lead to a compensatory response in the unirradiated kidney. The presence of the unirradiated contralateral kidney may effectively prevent the irradiated kidney from expressing any potential for repair and/or recovery of function. If this were true then the question would obviously arise, does the irradiated kidney retain some capacity for recovery? In order to answer this question, the contralateral unirradiated kidney was removed from pigs 26 weeks after the irradiation of the other kidney. The subsequent response of the irradiated kidney to nephrectomy was assessed in terms of the changes in renal size and haemodynamics, i.e. GFR and effective renal plasma flow (ERPF). (Auth.)

  3. Safety analysis report for packaging: the ORNL HFIR unirradiated fuel element shipping container

    International Nuclear Information System (INIS)

    Evans, J.H.; Boulet, J.A.M.; Eversole, R.E.

    1977-11-01

    The ORNL HFIR unirradiated fuel element shipping container was designed and fabricated at the Oak Ridge National Laboratory for the transport of HFIR unirradiated fuel elements. The container was evaluated analytically and experimentally to determine its compliance with the applicable regulations governing containers in which radioactive and fissile materials are transported, and the evaluation is the subject of this report. Computational and test procedures were used to determine the structural integrity and thermal behavior of the cask relative to the general standards for normal conditions of transport and the standards for the hypothetical accident conditions. The results of the evaluation demonstrate that the container is in compliance with the applicable regulations

  4. Magazine Influence on Cartridge Case Ejection Patterns with Glock Pistols.

    Science.gov (United States)

    Kerkhoff, Wim; Alberink, Ivo; Mattijssen, Erwin J A T

    2018-01-01

    In this study, the cartridge case ejection patterns of six different Glock model pistols (one specimen per model) were compared under three conditions: firing with a loaded magazine, an empty magazine, and without magazine. The distances, covered by the ejected cartridge cases given these three conditions, were compared for each of the six models. A significant difference was found between the groups of data for each of the tested specimens. This indicates that it is important that, to reconstruct a shooting scene incident based on the ejection patterns of a pistol, test shots are fired with the same pistol type and under the correct magazine condition. © 2017 American Academy of Forensic Sciences.

  5. The dissolution of unirradiated UO2 fuel pellets under simulated disposal conditions

    International Nuclear Information System (INIS)

    Ollila, K.; Leino-Forsman, H.

    1993-03-01

    The dissolution behaviour of unirradiated UO 2 pellets was studied as a function of water composition under oxidizing and reducing conditions at 25 deg C. The waters included deionized water as the reference water, sodium bicarbonate solutions with varying bicarbonate content, and two different synthetic groundwaters. The release of uranium was measured during static batch dissolution experiments of long duration (3-4 years)

  6. 42 CFR 84.194 - Filters used with chemical cartridges; location; replacement.

    Science.gov (United States)

    2010-10-01

    ...; replacement. 84.194 Section 84.194 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN...; replacement. (a) Particulate matter filters used in conjunction with a chemical cartridge shall be located on... replacement on the cartridge. ...

  7. In vivo genetic toxicity studies in Chinese hamsters fed irradiated or unirradiated foodstuffs

    International Nuclear Information System (INIS)

    Altmann, H.

    1982-01-01

    Two in vivo genetic toxicity studies were performed in Chinese hamsters fed irradiated or unirradiated diets of chicken, fish or dates in order to detect possible mutagenic effects caused by irradiating these foodstuffs. The tests selected for study were: 1. Chromosomal analysis of bone narrow cells and 2. DNA metabolism in spleen cells. Chicken, fish and dates were irradiated with doses of 7, 2.5 and 1 kGy respectively. These investigations were subsequently extended to include the effects of irradiated dried onions, pulses and cocoa beans on DNA metabolism in Chinese hamster spleen cells only. Dried onions were irradiated with doses of 0.15, 9 and 15 kGy, pulses with 10 kGy and cocoa beans with 3.2 to 5 kGy. In addition, a fumigated cocoa bean group was included. No significant differences in chromosomal aberration rate were detected between groups fed irradiated or unirradiated diets. Dried dates, whether irradiated or not, showed some evidence of genetic toxicity in their effect on DNA metabolism in the spleen cells of Chinese hamsters. Both date diets caused more strand breaks DNA than are usual for Chinese hamster spleen cells, but DNA repair was not adversely affected. Chicken, both irradiated and unirradiated, was found to enhance replicative DNA synthesis but had no effect on the DNA repair process. Irradiated fish, however, caused enhanced DNA synthesis compared to unirradiated fish, but also had no adverse effect on DNA repair. Irradiated white beans also enhanced DNA synthesis compared to controls whereas unirradiated samples inhibited synthesis. (orig./MG)

  8. Sensitivity analysis overlaps of friction elements in cartridge seals

    Directory of Open Access Journals (Sweden)

    Žmindák Milan

    2018-01-01

    Full Text Available Cartridge seals are self-contained units consisting of a shaft sleeve, seals, and gland plate. The applications of mechanical seals are numerous. The most common example of application is in bearing production for automobile industry. This paper deals with the sensitivity analysis of overlaps friction elements in cartridge seal and their influence on the friction torque sealing and compressive force. Furthermore, it describes materials for the manufacture of sealings, approaches usually used to solution of hyperelastic materials by FEM and short introduction into the topic wheel bearings. The practical part contains one of the approach for measurement friction torque, which results were used to specifying the methodology and precision of FEM calculation realized by software ANSYS WORKBENCH. This part also contains the sensitivity analysis of overlaps friction elements.

  9. A review of the rates of reaction of unirradiated uranium in gaseous atmospheres

    International Nuclear Information System (INIS)

    Pearce, R.J.

    1989-10-01

    The review collates available quantitative rate data for the reaction of unirradiated uranium in dry and moist air, steam and carbon dioxide based atmospheres at temperatures ranging from room temperature to above the melting point of uranium. Reactions in nitrogen and carbon monoxide are also considered. The aim of the review is to provide a compilation of base data for the hazard analysis of fault conditions relating to Magnox fuel. (author)

  10. Combustible Cartridge Cases: Current Status and Future Prospects

    Science.gov (United States)

    1992-08-01

    and presents new models of combustible cartridge case burning . Following a summary of experimental data, it concludes with proposals for further...UNCLASSIFIED UNCLASSIFIED UNCLASSIFIED SAR NSN 7540-01-280-5500 Standard Form 298 (Rev 2-89) Precribed by ANSI Std Z39-19 IWFENTIONALLY LEFT BLANK...7 3.3 In-Depth Burning Model ........................................ 7 3.3.1 M odel A ................................................ 9 3.3.2

  11. A highway accident involving unirradiated nuclear fuel in Springfield, Massachusetts, on December 16, 1991

    International Nuclear Information System (INIS)

    Carlson, R.W.; Fischer, L.E.

    1992-06-01

    In the early morning of Dec. 16, 1991, a severe accident occurred when a passenger vehicle traveling in the wrong direction collided with a tractor trailer carrying 24 unirradiated nuclear fuel assemblies in 12 containers on Interstate I-91 in Springfield, Massachusetts. The purpose of this report is to document the mechanical circumstances of the severe accident, confirm the nature and quantity of the radioactive materials involved, and assess the physical environment to which the containers were exposed and the response of the containers and their contents. The report consists of five major sections. The first section describes the circumstances and conditions of the accident and the finding of facts. The second describes the containers, the unirradiated nuclear fuel assemblies, and the tie down arrangement used for the trailer. The third describes the damage sustained during the accident to the tractor, trailer, containers, and unirradiated nuclear fuel assemblies. The fourth evaluates the accident environment and its effects on the containers and their contents. The final section gives conclusions derived from the analysis and fact finding investigation. During this severe accident, only minor injuries occurred, and at no time was the public health and safety at risk

  12. High Temperature Tensile Properties of Unirradiated and Neutron Irradiated 20 Cr-35 Ni Austenitic Steel

    Energy Technology Data Exchange (ETDEWEB)

    Roy, R B; Solly, B

    1966-12-15

    The tensile properties of an unirradiated and neutron irradiated (at 40 deg C) 20 % Cr, 35 % Ni austenitic steel have been studied at 650 deg C, 750 deg C and 820 deg C. The tensile elongation and mode of fracture (transgranular) of unirradiated specimens tested at room temperature and 650 deg C are almost identical. At 750 deg C and 820 deg C the elongation decreases considerably and a large part of the total elongation is non-uniform. Furthermore, the mode of fracture at these temperatures is intergranular and microscopic evidence suggests that fracture is caused by formation and linkup of grain boundary cavities. YS and UTS decrease monotonically with temperature. Irradiated specimens show a further decrease in ductility and an increase in the tendency to grain boundary cracking. Irradiation has no significant effect on the YS, but the UTS are reduced. The embrittlement of the irradiated specimens is attributed to the presence of He and Li atoms produced during irradiation and the possible mechanisms are discussed. Prolonged annealing of irradiated and unirradiated specimens at 650 deg C appears to have no significant effect on tensile properties.

  13. Results from In-pile experiments on LWR fuel rod behavior under LOCA conditions with unirradiated rods

    International Nuclear Information System (INIS)

    Sepold, L.; Karb, E.H.; Pruessmann, M.

    1981-06-01

    This report summarizes the results of the FR2-in-pile tests at KfK (Kernforschungszentrum Karlsruhe) with unirradiated test rods. The in-pile tests with the objective of investigating the influence of a nuclear environment on the mechanisms of fuel rod failure were being performed with irradiated and unirradiated single rods of a PWR design in the DK loop of the FR2 reactor. The main parameter of the test program was the burnup, ranging from 2.500 to 35.000 MWd/t. The program with unirradiated specimens comprised the series A and B with a total of 14 tests. (orig.) [de

  14. Plant-scale anodic dissolution of unirradiated N-Reactor fuel

    International Nuclear Information System (INIS)

    Gay, E.C.; Miller, W.E.; Laidler, J.J.

    1995-01-01

    Anodic dissolution tests were made with unirradiated N-Reactor fuel to determine the fuel segment length, diameter, and shape required for high throughput electrorefiner treatment for ultimate disposal in a geologic repository. Based on these tests, a conceptual design was produced of an electrorefiner for a full-scale plant to process N-Reactor spent fuel. In this design, the diameter of an electrode assembly is about 0.6 m (25 in.). Eight of these assemblies in an electrorefiner would accommodate a 1.333-metric-ton batch of N-Reactor fuel. Electrorefining would proceed at a rate of 40 kg uranium per hour

  15. Damage and failure of unirradiated and irradiated fuel rods tested under film boiling conditions

    International Nuclear Information System (INIS)

    Mehner, A.S.; Hobbins, R.R.; Seiffert, S.L.; MacDonald, P.E.; McCardell, R.K.

    1979-01-01

    Power-cooling-mismatch experiments are being conducted as part of the Thermal Fuels Behavior Program in the Power Burst Facility at the Idaho National Engineering Laboratory to evaluate the behavior of unirradiated and previously irradiated light water reactor fuel rods tested under stable film boiling conditions. The observed damage that occurs to the fuel rod cladding and the fuel as a result of film boiling operation is reported. Analyses performed as a part of the study on the effects of operating failed fuel rods in film boiling, and rod failure mechanisms due to cladding embrittlement and cladding melting upon being contacted by molten fuel are summarized

  16. Safety Analysis Report for Packaging: The unirradiated fuel shipping container USA/9853/AF

    International Nuclear Information System (INIS)

    1991-01-01

    The HFBR Unirradiated Fuel Shipping Container was designed and fabricated at the Oak Ridge National Laboratory in 1978 for the transport of fuel for the High Flux Beam Reactor (HFBR) for Brookhaven National Laboratory. The package has been evaluated analytically, as well as the comparison to tests on similar packages, to demonstrate compliance with the applicable regulations governing packages in which radioactive and fissile materials are transported. The contents of this Safety Analysis Report for Packaging (SARP) are based on Regulatory Guide 7.9 (proposed Revision 2 - May 1986), 10 CFR Part 71, DOE Order 1540.2, DOE Order 5480.3, and 49 CFR Part 173

  17. Characteristics of a cartridge NEG (St101 Zr-Al)

    International Nuclear Information System (INIS)

    Hisamatsu, Hiromi; Shimamoto, Masayuki; Kanazawa, Ken-ichi; Ishimaru, Hajime

    1990-01-01

    The report addresses the application of a non-evaporable getter (NEG) pump to an accelerator (storage ring). Tests are performed to determine major characteristics of the non-evaporable getter pump in an effort to provide a method for its efficient use. Test results show that with an St101 cartridge NEG pump, it is possible to produce an ultrahigh vacuum in a system with a surface area of about 10 4 cm 2 through baking at 410K for two hours. Once activated at 1000K, a NEG pump recovers a pumping performance in a subsequent test run at 723K, though the pumping speed decreases by several tens of percent. The St-101 cartridge type NEG pump is at least 2 Pam 3 in pumping capacity for carbon monoxide. The pumping speed decreases with an increasing amount of occluded carbon monoxide. Upon activation, most of the occluded carbon monoxide diffuses into the pump while only little of it is released into the gas phase. Its diffusion through the surface of the NEG pump can occur even at room temperature, indicating that if a leak takes place, the pump would absorb the gas continuously. Thus, if a leak occurs during activation, the pump would occlude a large amount of gas and therefore, activation should be carried out with careful checking for a leak. (N.K.)

  18. Bubble Jet agent release cartridge for chemical single cell stimulation.

    Science.gov (United States)

    Wangler, N; Welsche, M; Blazek, M; Blessing, M; Vervliet-Scheebaum, M; Reski, R; Müller, C; Reinecke, H; Steigert, J; Roth, G; Zengerle, R; Paust, N

    2013-02-01

    We present a new method for the distinct specific chemical stimulation of single cells and small cell clusters within their natural environment. By single-drop release of chemical agents with droplets in size of typical cell diameters (d agent release cartridge with integrated fluidic structures and integrated agent reservoirs are shown, tested, and compared in this publication. The single channel setup features a fluidic structure fabricated by anisotropic etching of silicon. To allow for simultaneous release of different agents even though maintaining the same device size, the second type comprises a double channel fluidic structure, fabricated by photolithographic patterning of TMMF. Dispensed droplet volumes are V = 15 pl and V = 10 pl for the silicon and the TMMF based setups, respectively. Utilizing the agent release cartridges, the application in biological assays was demonstrated by hormone-stimulated premature bud formation in Physcomitrella patens and the individual staining of one single L 929 cell within a confluent grown cell culture.

  19. The effect of compressive stress on the Young's modulus of unirradiated and irradiated nuclear graphites

    International Nuclear Information System (INIS)

    Oku, T.; Usui, T.; Ero, M.; Fukuda, Y.

    1977-01-01

    The Young's moduli of unirradiated and high temperature (800 to 1000 0 C) irradiated graphites for HTGR were measured by the ultrasonic method in the direction of applied compressive stress during and after stressing. The Young's moduli of all the tested graphites decreased with increasing compressive stress both during and after stressing. In order to investigate the reason for the decrease in Young's modulus by applying compressive stress, the mercury pore diameter distributions of a part of the unirradiated and irradiated specimens were measured. The change in pore distribution is believed to be associated with structural changes produced by irradiation and compressive stressing. The residual strain, after removing the compressive stress, showed a good correlation with the decrease in Young's modulus caused by the compressive stress. The decrease in Young's modulus by applying compressive stress was considered to be due to the increase in the mobile dislocation density and the growth or formation of cracks. The results suggest, however, that the mechanism giving the larger contribution depends on the brand of graphite, and in anisotropic graphite it depends on the direction of applied stress and the irradiation conditions. (author)

  20. Molecular dynamics study on interfacial thermal conductance of unirradiated and irradiated SiC/C

    International Nuclear Information System (INIS)

    Wang, Qingyu; Wang, Chenglong; Zhang, Yue; Li, Taosheng

    2014-01-01

    SiC f /SiC composite materials have been considered as candidate structural materials for several types of advanced nuclear reactors. Both experimental and computer simulations studies have revealed the degradation of thermal conductivity for this material after irradiation. The objective of this study is to investigate the effect of SiC/graphite interface structure and irradiation on the interfacial thermal conductance by using molecular dynamics simulation. Five SiC/graphite composite models were created with different interface structures, and irradiation was introduced near the interfaces. Thermal conductance was calculated by means of reverse-NEMD method. Results show that there is a positive correlation between the interfacial energy and interfacial C–Si bond quantity, and irradiated models showed higher interfacial energy compared with their unirradiated counterparts. Except the model with graphite atom plane parallel to the interface, the interfacial thermal conductance of unirradiated and irradiated (1000 eV) models, increases as the increase of interfacial energy, respectively. For all irradiated models, lattice defects are of importance in impacting the interfacial thermal conductance depending on the interface structure. For the model with graphite layer parallel to the interface, the interfacial thermal conductance increased after irradiation, for the other models the interfacial thermal conductance decreased. The vibrational density of states of atoms in the interfacial region was calculated to analyze the phonon mismatch at the interface

  1. Thermogravimetric studies of the thermo-oxidative stability of irradiated and unirradiated polyethylene

    International Nuclear Information System (INIS)

    Novakovic, L.; Gal, O.; Markovic, V.; Stannett, V.T.

    1985-01-01

    In part one of this series the effects of a phenolic, an amine and a thioester antioxidant on the thermo-oxidative stability of irradiated and unirradiated low-density polyethylene was reported. In this paper the effects of combined phenolic and thioester stabilizers are described. Isothermal thermogravimetric analysis was used to study the systems. Pronounced synergism was observed with the induction periods, the time when the initial weight loss begins and the 5% weight loss. At about 50% of each stabilizer increases greater than twofold were observed both with the unirradiated and irradiated polymers. The rate constants for oxygen uptake were decreased. However, the rates of degradation at 5% weight loss fell between the values of the two pure stabilizers with no pronounced synergism in either case. In the absence of oxygen little effect of either antioxidant or their mixtures was observed. The corresponding activation energies were somewhat higher, however, with the irradiated samples containing antioxidants. Dynamic thermogravimetry was used for this study. A kinetic analysis indicated that there were somewhat different modes of degradation at lower- and higher-temperature ranges. (author)

  2. Thermogravimetric studies of the thermo-oxidative stability of irradiated and unirradiated polyethylene. 2. Combined antioxidants

    Energy Technology Data Exchange (ETDEWEB)

    Novakovic, L; Gal, O; Markovic, V; Stannett, V T

    1985-01-01

    In part one of this series the effects of a phenolic, an amine and a thioester antioxidant on the thermo-oxidative stability of irradiated and unirradiated low-density polyethylene was reported. In this paper the effects of combined phenolic and thioester stabilizers are described. Isothermal thermogravimetric analysis was used to study the systems. Pronounced synergism was observed with the induction periods, the time when the initial weight loss begins and the 5% weight loss. At about 50% of each stabilizer increases greater than twofold were observed both with the unirradiated and irradiated polymers. The rate constants for oxygen uptake were decreased. However, the rates of degradation at 5% weight loss fell between the values of the two pure stabilizers with no pronounced synergism in either case. In the absence of oxygen little effect of either antioxidant or their mixtures was observed. The corresponding activation energies were somewhat higher, however, with the irradiated samples containing antioxidants. Dynamic thermogravimetry was used for this study. A kinetic analysis indicated that there were somewhat different modes of degradation at lower- and higher-temperature ranges. (author).

  3. Histochemical differentiation between unirradiated and gamma-irradiated tissue in commercial use of some irradiated vegetables

    International Nuclear Information System (INIS)

    Foa, E.

    1978-01-01

    The use of gamma irradiation as a commercial method for the preservation of fruits and vegetables calls for methods of differentiation between unirradiated and irradiated products. A new approach to studying the influence of gamma irradiation on vegetable tissue at the cellular level by histochemical techniques has been developed by the authors and already applied to a number of fruits and vegetables. The possibility of evidencing radiation effects in the polysaccharide components of the cell wall suggested that these detected differences could be applied to differentiate irradiated from unirradiated tomatoes and potatoes. Some work done to determine changes in the cell wall polysaccharides of gamma-irradiated potatoes and tomatoes and to relate these changes to some other factors, such as storage time and vegetable variety, is reported here. While significant differences have been found in the optical densities of the total polysaccharides of the cell wall as a function of irradiation and of the other variables mentioned, it is not yet possible to use these values as a means of reliable differentiation. (author)

  4. Alterations in a Unique Class of Cortical Chandelier Cell Axon Cartridges in Schizophrenia.

    Science.gov (United States)

    Rocco, Brad R; DeDionisio, Adam M; Lewis, David A; Fish, Kenneth N

    2017-07-01

    The axons of chandelier cells (ChCs) target the axon initial segment of pyramidal neurons, forming an array of boutons termed a cartridge. In schizophrenia, the density of cartridges detectable by gamma-aminobutyric acid (GABA) membrane transporter 1 immunoreactivity is lower, whereas the density of axon initial segments detectable by immunoreactivity for the α2 subunit of the GABA A receptor is higher in layers 2/superficial 3 of the prefrontal cortex. These findings were interpreted as compensatory responses to lower GABA levels in ChCs. However, we recently found that in schizophrenia, ChC cartridge boutons contain normal levels of the 67 kDa isoform of glutamic acid decarboxylase (GAD67) protein, the enzyme responsible for GABA synthesis in these boutons. To understand these findings we quantified the densities of ChC cartridges immunoreactive for vesicular GABA transporter (vGAT+), which is present in all cartridge boutons, and the subset of cartridges that contain calbindin (CB+). Prefrontal cortex tissue sections from 20 matched pairs of schizophrenia and unaffected comparison subjects were immunolabeled for vGAT, GAD67, and CB. The mean density of vGAT+/CB+ cartridges was 2.7-fold higher, exclusively in layer 2 of schizophrenia subjects, whereas the density of vGAT+/CB- cartridges did not differ between subject groups. Neither vGAT, CB, or GAD67 protein levels per ChC bouton nor the number of boutons per cartridge differed between subject groups. Our findings of a greater density of CB+ ChC cartridges in prefrontal cortex layer 2 from schizophrenia subjects suggests that the normal developmental pruning of these cartridges is blunted in the illness. Copyright © 2016 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

  5. 42 CFR 84.1155 - Filters used with canisters and cartridges; location; replacement.

    Science.gov (United States)

    2010-10-01

    ...; location; replacement. 84.1155 Section 84.1155 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH... Efficiency Respirators and Combination Gas Masks § 84.1155 Filters used with canisters and cartridges; location; replacement. (a) Particulate matter filters used in conjunction with a canister or cartridge...

  6. Thermal studies on unirradiated and γ-irradiated polymer of allyl diglycol carbonate

    International Nuclear Information System (INIS)

    Kalsi, P.C.; Pandey, A.K.; Iyer, R.H.; Singh Mudher, K.D.

    1995-01-01

    The thermal decomposition of unirradiated and γ-irradiated (5.93-15.5 MRad dose range) allyl diglycol carbonate polymer (trade name, CR-39) was studied by thermogravimetry (TG) and differential thermal analysis (DTA). These studies indicate four main decomposition steps in CR-39 polymer in air. Assessment of the influence of radiation dose on the above range shows that while the 5.93 MRad γ-irradiated polymer CR-39 degrades in three steps, the 15.5 MRad γ-irradiated polymer degrades in only two steps. The kinetics of the different stages of degradation were also evaluated from the TG curves. Irradiation enhances the decomposition rate and the effect increases further with increasing radiation dose. The activation energy values calculated for all the decomposition stages decrease on irradiation

  7. Reactor Materials Program electrochemical potential measurements by ORNL with unirradiated and irradiated stainless steel specimens

    International Nuclear Information System (INIS)

    Baumann, E.W.; Caskey, G.R. Jr.

    1993-07-01

    Effect of irradiation of stainless steel on electrochemical potential (ECP) was investigated by measurements in dilute HNO 3 and H 2 O 2 solutions, conditions simulating reactor moderator. The electrodes were made from unirradiated/irradiated, unsensitized/sensitized specimens from R-reactor piping. Results were inconclusive because of budgetary restrictions. The dose rate may have been too small to produce a significant radiolytic effect. Neither the earlier CERT corrosion susceptibility tests nor the present ECP measurements showed a pronounced effect of irradiation on susceptibility of the stainless steel to IGSCC; this is confirmed by the absence in the stainless steel of the SRS reactor tanks (except for the C Reactor tank knuckle area)

  8. Bakery products from irradiated and unirradiated eggs - detection of irradiation in a processed food

    International Nuclear Information System (INIS)

    Pfordt, J.; Grabowski, H.U. von

    1995-01-01

    The detection of radiation-specific degradation products in fat has become an established method which has successfully been applied to egg products. This study is making evident the detectability of irradiated eggs as an ingredient of specified processed foods. Tart layers were produced from both irradiated and non-irradiated liquid whole egg. When the fat components were isolated from the tart layers and investigated by GC/MS, the presence of irradiated eggs could clearly be shown. While the radiation-induced hydrocarbons and 2-alkylcyclobutanones could not be found in unirradiated samples, tart layers from irradiated eggs contained these substances. Especially for the hydrocarbons a satisfying correlation between radiation dose and concentration could be observed. The concentrations of radiation-induced compounds were generally lower in the tart layers than in the liquid egg samples they had been produced from. (orig.) [de

  9. Evaluation of staphylococcus aureus growth in unirradiated and irradiated cured meats using the Gompertz equation

    International Nuclear Information System (INIS)

    Szczawinski, J.; Szczawinska, M.

    1993-01-01

    1. Sodium nitrite, in concentration of 156 mg/kg, exerted little (from practical point of view) inhibitory effect on S. aureus in cured meat. Its addition caused lag time extension, increase of exponential growth rate, decrease of generation time and maximum population density of staphylococci in samples of cured meat stored at 20 C. 2. Growth curves of Staphylococcus aureus in unirradiated and irradiated (50 kGy) meats cured without sodium nitrite were similar. 3. Irradiation of meat cured with 156 mg/kg sodium nitrite with increasing doses of ionizing radiation (0, 10, 30, 50 kGy) progressively decreased growth rates and lag time and increased generation time and maximum population densities of Staphylococcus aureus in samples inoculated after radiation treatment and incubated at 20 C. (orig.)

  10. Reactor Materials Program electrochemical potential measurements by ORNL with unirradiated and irradiated stainless steel specimens

    Energy Technology Data Exchange (ETDEWEB)

    Baumann, E.W.; Caskey, G.R. Jr.

    1993-07-01

    Effect of irradiation of stainless steel on electrochemical potential (ECP) was investigated by measurements in dilute HNO{sub 3} and H{sub 2}O{sub 2} solutions, conditions simulating reactor moderator. The electrodes were made from unirradiated/irradiated, unsensitized/sensitized specimens from R-reactor piping. Results were inconclusive because of budgetary restrictions. The dose rate may have been too small to produce a significant radiolytic effect. Neither the earlier CERT corrosion susceptibility tests nor the present ECP measurements showed a pronounced effect of irradiation on susceptibility of the stainless steel to IGSCC; this is confirmed by the absence in the stainless steel of the SRS reactor tanks (except for the C Reactor tank knuckle area).

  11. Erythrokinetics in mice bearing tumours in either preirradiated or unirradiated tissue

    International Nuclear Information System (INIS)

    Jirtle, R.L.; Clifton, K.H.

    1978-01-01

    Experiments were designed to clarify the causes of anaemia in hosts bearing tumours in either unirradiated or preirradiated tissue. Isotopic methods are described which enable the estimation of erythrocyte destruction and production rates, and the potential red cell life spans in tumour-bearing animals. In this experimental system, anaemia (a) is in large part due to accelerated random erythrocyte loss, (b) is exacerbated as tumours grow by a progressive reduction in the potential erythrocyte life span due to intrinsic erythrocyte defects. (c) is accompanied by an increase in erythrocyte production of six- to ten-fold and (d) is postponed in onset and decreased in magnitude by preirradiation of the tumour transplant site. (author)

  12. Kinetics of thermal decomposition of γ-irradiated and unirradiated complexes of mandelhydroxamic acid

    International Nuclear Information System (INIS)

    Hassan, R.M.; Farid, T.; El-Bellihi, A.A.

    1992-01-01

    The thermal decomposition of γ-irradiated and unirradiated complexes of mandelhydroxamic acid (HMA), Co (HMA) 2 .1/2H 2 O, Mn (HMA) 2 .2H 2 O, Ba (HMA) 2 .2H 2 O and Cd (HMA) 2 .2H 2 O have been studied thermogravimetrically (under isothermal conditions). The thermal dehydration of each complex occured in one step, while the decomposition of dehydrated complexes occured in two steps. The kinetic parameters for dehydration were computed by different models. The thermal dehydration is regulated by random nucleation A 3 for Co-, Mn-, and Cd-complexes and by phase-boundary (R 3 ) for Ba-complex. The effect of γ-irradiation on the kinetic parameters of thermal decomposition is discussed. Radiation did not modify the mechanism of the reaction but accelarated the dehydration steps in the case of Mn- and Co-complexes. (author) 7 refs.; 1 fig.; 4 tabs

  13. Effect of helium pressure on the response of unirradiated UO2 subjected to thermal transients

    International Nuclear Information System (INIS)

    Fenske, G.R.; Chapello, P.M.; Emerson, J.E.; Poeppel, R.B.

    1983-01-01

    The effect of helium pressure on the transient response of unirradiated depleted UO 2 subjected to simulated hypothetical loss-of-flow accidents in a gas-cooled fast reactor was examined by use of the direct electrical heating technique. Transient tests were performed at pressures ranging from 7 to 10 X 10 5 Pa(7 to 10 atm) to 7 to 8 MPa (70 to 80 atm) on radially restrained and unrestrained fuel segments. The average heating rates ranged from about17 to 240 J/g x s. The results indicate that while the mechanical integrity of the fuel segment was independent of the test pressure, the rapid ejection of molten fuel from pellet interfaces of unrestrained fuel, observed at the lower pressures, was delayed or suppressed at the higher pressures

  14. Overview and Critical Assessment of the Tensile Properties of unirradiated and irradiated EUROFER97

    Energy Technology Data Exchange (ETDEWEB)

    Lucon, E.; Vandermeulen, W.

    2007-10-15

    Material research represents a crucial issue for the assessment of fusion as a future viable source of energy. Structural materials, in particular, need to show a superior mechanical and chemical behaviour to guarantee the safe operation of the reactor during its whole lifetime, while retaining low activation characteristics to minimise the environmental impact of the produced waste. In this context, specific efforts have been focused for the last twenty years in Europe, Japan and the US, on developing suitable Reduced Activation Ferritic Martensitic (RAFM) steels as candidate structural materials. EUROFER97 has recently emerged in Europe as the reference material for the DEMO design. In the framework of the Long-Term Programme of EFDA (European Fusion Development Agreement), a coordinated effort has been launched aimed at providing a critical assessment of the mechanical and microstructural properties of EUROFER97 in the unirradiated and irradiated conditions, based on the results accumulated since the late 90ies within numerous EFDA tasks.

  15. Plant-scale anodic dissolution of unirradiated N-Reactor fuel

    International Nuclear Information System (INIS)

    Gay, E.C.; Miller, W.E.; Laidler, J.J.

    1995-01-01

    Anodic dissolution tests were made with unirradiated N-Reactor fuel to determine the fuel segment length, diameter, and shape required for high throughput electro-refiner treatment for ultimate disposal in a geologic repository. Based on these tests, a conceptual design was produced of an electro-refiner for a full-scale plant to process N-Reactor spent fuel. In this design, the diameter of an electrode assembly is about 0.6 m (25 in.). Eight of these assemblies in an electro-refiner would accommodate a 1.333-metric-ton batch of N-Reactor fuel. Electrorefining would proceed at a rate of 40 kg uranium per hour. (author)

  16. Erythrokinetics in mice bearing tumours in either preirradiated or unirradiated tissue

    Energy Technology Data Exchange (ETDEWEB)

    Jirtle, R L; Clifton, K H [Wisconsin Univ., Madison (USA). Div. of Clinical Oncology

    1978-11-01

    Experiments were designed to clarify the causes of anaemia in hosts bearing tumours in either unirradiated or preirradiated tissue. Isotopic methods are described which enable the estimation of erythrocyte destruction and production rates, and the potential red cell life spans in tumour-bearing animals. In this experimental system, anaemia (a) is in large part due to accelerated random erythrocyte loss, (b) is exacerbated as tumours grow by a progressive reduction in the potential erythrocyte life span due to intrinsic erythrocyte defects. (c) is accompanied by an increase in erythrocyte production of six- to ten-fold and (d) is postponed in onset and decreased in magnitude by preirradiation of the tumour transplant site.

  17. Chromosome dosimetry: the influence of culture media on the proliferation of irradiated and unirradiated human lymphocytes

    International Nuclear Information System (INIS)

    Purrott, R.J.; Lloyd, D.C.; Vulpis, N.

    1981-01-01

    The proliferation of phytohaemagglutinin stimulated human lymphocytes in four types of synthetic culture medium has been studied using the fluorescence plus Giemsa staining technique to determine cell cycle status. 48 hour cultures of unirradiated cells containing Ham's F10 or RPMI 1640 media yielded significant numbers of second cycle metaphases. Cultures containing Eagle's MEM or TC 199 media, however, required longer incubation times to produce appreciable numbers of second division cells. Intrinsic differences between donors in the rate of proliferation had little effect on the relative ranking of the media. Radiation induced mitotic delay of about 1 hour per Gray was observed for each medium. The relevance of these results to the accuracy of radiation dose estimation by chromosome aberration analysis is discussed. (author)

  18. Evaluation and comparison of a national made dental cartridge with two foreign made

    Directory of Open Access Journals (Sweden)

    Mahmood Hashemi H

    2006-06-01

    Full Text Available Background and Aim: Several factories produce dental cartridge in the world. In Iran, Daroupakhsh company is responsible for this task. The aim of this study was evaluate some properties of daroupakhsh cartridge and compare them with two imported ones: Ecocaine (made in Italy and Septodont (made in France. Materials and Methods: In this experimental study, 70 healthy patients from maxillofacial clinic of Shariaty hospital were selected. After obtaining informed consent, 0.1 cc of each carpule was injected to the patients' frontal region and the extent of anesthesia was measured at different time intervals. Also the quality of injections was evaluated by 11 surgeons. The dimensions of the three cartridges were also measured and compared together. Data were analyzed by repeated measure ANOVA and Friedman with p<0.05 as the limit of significance. Results: There was no significant difference in extent and duration of anesthesia among the studied cartridges. Surgeons were equally satisfied of all three kinds of cartridges. All of the cartridges were aspirable. Conclusion: Based on the results of this study, the three studied cartridges had similar properties.

  19. Sperm quantity and size variation in un-irradiated and irradiated males of the malaria mosquito Anopheles arabiensis Patton

    NARCIS (Netherlands)

    Helinski, M.; Knols, B.G.J.

    2009-01-01

    Anopheles mosquitoes are important candidates for genetic control strategies. However, little is known about sperm quality and quantity as determinants of male reproductive success. In this study, sperm quantity and length variation were assessed in testes of un-irradiated and irradiated Anopheles

  20. Response of unirradiated and irradiated PWR fuel rods tested under power-cooling-mismatch conditions

    International Nuclear Information System (INIS)

    MacDonald, P.E.; Quapp, W.J.; Martinson, Z.R.; McCardell, R.K.; Mehner, A.S.

    1978-01-01

    This report summarizes the results from the single-rod power-cooling-mismatch (PCM) and irradiation effects (IE) tests conducted to date in the Power Burst Facility (PBF) at the U.S. DOE Idaho National Engineering Laboratory. This work was performed for the U.S. NRC under contact to the Department of Energy. These tests are part of the NRC Fuel Behavior Program, which is designed to provide data for the development and verification of analytical fuel behavior models that are used to predict fuel response to abnormal or postulated accident conditions in commercial LWRs. The mechanical, chemical and thermal response of both previously unirradiated and previously irradiated LWR-type fuel rods tested under power-cooling-mismatch condition is discussed. A brief description of the test designs is presented. The results of the PCM thermal-hydraulic studies are summarized. Primary emphasis is placed on the behavior of the fuel and cladding during and after stable film boiling. (orig.) [de

  1. An analysis of facial nerve function in irradiated and unirradiated facial nerve grafts

    International Nuclear Information System (INIS)

    Brown, Paul D.; Eshleman, Jeffrey S.; Foote, Robert L.; Strome, Scott E.

    2000-01-01

    Purpose: The effect of high-dose radiation therapy on facial nerve grafts is controversial. Some authors believe radiotherapy is so detrimental to the outcome of facial nerve graft function that dynamic or static slings should be performed instead of facial nerve grafts in all patients who are to receive postoperative radiation therapy. Unfortunately, the facial function achieved with dynamic and static slings is almost always inferior to that after facial nerve grafts. In this retrospective study, we compared facial nerve function in irradiated and unirradiated nerve grafts. Methods and Materials: The medical records of 818 patients with neoplasms involving the parotid gland who received treatment between 1974 and 1997 were reviewed, of whom 66 underwent facial nerve grafting. Fourteen patients who died or had a recurrence less than a year after their facial nerve graft were excluded. The median follow-up for the remaining 52 patients was 10.6 years. Cable nerve grafts were performed in 50 patients and direct anastomoses of the facial nerve in two. Facial nerve function was scored by means of the House-Brackmann (H-B) facial grading system. Twenty-eight of the 52 patients received postoperative radiotherapy. The median time from nerve grafting to start of radiotherapy was 5.1 weeks. The median and mean doses of radiation were 6000 and 6033 cGy, respectively, for the irradiated grafts. One patient received preoperative radiotherapy to a total dose of 5000 cGy in 25 fractions and underwent surgery 1 month after the completion of radiotherapy. This patient was placed, by convention, in the irradiated facial nerve graft cohort. Results: Potential prognostic factors for facial nerve function such as age, gender, extent of surgery at the time of nerve grafting, preoperative facial nerve palsy, duration of preoperative palsy if present, or number of previous operations in the parotid bed were relatively well balanced between irradiated and unirradiated patients. However

  2. A Criticality Safety Study on Storing Unirradiated Cintichem-Type Targets at Sandia National Laboratories

    International Nuclear Information System (INIS)

    Romero, D.J.; Parma, E.J.; Busch, R.D.

    1999-01-01

    This criticality safety analysis is performed to determine the effective multiplication factor (k eff ) for a storage cabinet filled with unirradiated Cintichem-type targets. These targets will be used to produce 99 Mo at Sandia National Laboratories and will be stored on-site prior to irradiation in the Annular Core Research Reactor. The analysis consisted of using the Monte Carlo code MCNP (Version 4A) to model and predict the k eff for the proposed dry storage configuration under credible loss of geometry and moderator control. Effects of target pitch, non-uniform loading, and target internal/external flooding are evaluated. Further studies were done with deterministic methods to verify the results obtained from MCNP and to obtain a clearer understanding of the parameters affecting system criticality. The diffusion accelerated neutral particle transport code ONEDANT was used to model the target in a one-dimensional, infinite half-slab geometry and determine the critical slab thickness. Hand calculations were also completed to determine the critical slab thickness with modified one-group, and one-group, two region approximations. Results obtained from ONEDANT and the hand calculations were compared to applicable cases in a commonly used criticality safety analysis handbook. Overall, the critical slab thicknesses obtained in the deterministic analysis were much larger than the dimensions of the cabinet and further support the predictions by MCNP that a critical system cannot be attained for the base case or in conditions where loss of geometry and moderation control occur

  3. Fusarium growth on culture media made of tissue juice from irradiated and unirradiated potato tubers

    International Nuclear Information System (INIS)

    Taczanowski, M.

    1994-01-01

    Fusarium Sulphureum Schlecht is one of the tuber pathogens causing potato storage disease knowing as dry rot. Because irradiation can disturb the tissue defence mechanism against the pathogen, it was decided to carry out experiments on influence of the treatment on subsequent tuber tissue reaction to a maceration process. The maceration as a physical stress was a substitute for the pathogen activity. Tubers of two potato varieties were tested: Mila -a resistant variety to Fusarium and Atol - susceptible one. Tubers of both varieties were irradiated with a dose of 105 kGy. Unirradiated tubers were taken as a control. A day after irradiation the cortex tissue was macerated using an ordinary rasper and the resulted tissue pulp was strained through medical gauze to obtain crude juice. The juice was clarified by centrifugation and then added to dissolved PDA. The volume ratio of juice to PDA was 1:1. The prepared media were dispensed into Petri dishes. Small pieces of the Fusarium culture were put on the surface of the medium at the centre of each Petri dish. Subsequent growth of the fungus was assessed by measurement of culture diameters every 24 hours. Linear functions of the Fusarium growth were obtained for Mila control and Atol control. In the case of Mila, the Fusarium found more favourable conditions for its growth in the presence of juice from irradiated tubers than from the control ones. Making the same comparison for Atol, no difference was detected. (author)

  4. The reaction of unirradiated and irradiated nuclear graphites with water vapor in helium

    International Nuclear Information System (INIS)

    Imai, Hisashi; Nomura, Shinzo; Kurosawa, Takeshi; Fujii, Kimio; Sasaki, Yasuichi

    1980-10-01

    Nuclear graphites more than 10 brands were oxidized with water vapor in helium and then some selected graphites were irradiated with fast neutron in the Japan Materials Testing Reactor to clarify the effect of radiation damage of graphite on their reaction behaviors. The reaction was carried out under a well defined condition in the temperature range 800 -- 1000 0 C at concentrations of water vapor 0.38 -- 1.30 volume percent in helium flow of total pressure of 1 atm. The chemical reactivity of graphite irradiated at 1000 +- 50 0 C increased linearly with neutron fluence until irradiation of 3.2 x 10 21 n/cm 2 . The activation energy for the reaction was found to decrease with neutron fluence for almost all the graphites, except for a few ones. The order of reaction increased from 0.5 for the unirradiated graphite to 1.0 for the graphite irradiated up to 6.0 x 10 20 n/cm 2 . Experiment was also performed to study a superposed effect between the influence of radiation damage of graphite and the catalytic action of barium on the reaction rate, as well as the effect of catalyser of barium. It was shown that these effects were not superposed upon each other, although barium had a strong catalytic action on the reaction. (author)

  5. Nanoparticle separation with a miniaturized asymmetrical flow field-flow fractionation cartridge

    Science.gov (United States)

    Müller, David; Cattaneo, Stefano; Meier, Florian; Welz, Roland; deMello, Andrew

    2015-07-01

    Asymmetrical Flow Field-Flow Fractionation (AF4) is a separation technique applicable to particles over a wide size range. Despite the many advantages of AF4, its adoption in routine particle analysis is somewhat limited by the large footprint of currently available separation cartridges, extended analysis times and significant solvent consumption. To address these issues, we describe the fabrication and characterization of miniaturized AF4 cartridges. Key features of the scale-down platform include simplified cartridge and reagent handling, reduced analysis costs and higher throughput capacities. The separation performance of the miniaturized cartridge is assessed using certified gold and silver nanoparticle standards. Analysis of gold nanoparticle populations indicates shorter analysis times and increased sensitivity compared to conventional AF4 separation schemes. Moreover, nanoparticulate titanium dioxide populations exhibiting broad size distributions are analyzed in a rapid and efficient manner. Finally, the repeatability and reproducibility of the miniaturized platform are investigated with respect to analysis time and separation efficiency.

  6. EPA Region 8, Memo on Desktop Printer Ink Cartridges Policy & Voluntary Printer Turn-in

    Science.gov (United States)

    This memo requests EPA Region 8 users to voluntarily turn-in their desktop printers and notifies users of the Region 8 policy to not provide maintenance or ink and toner cartridges for desktop printers.

  7. The indicating FTA elute cartridge a solid sample carrier to detect high-risk HPV and high-grade cervical lesions

    NARCIS (Netherlands)

    Bie, R.P. de; Schmeink, C.E.; Bakkers, J.M.J.E.; Snijders, P.J.L.M.; Quint, W.G.V.; Massuger, L.F.A.G.; Bekkers, R.L.M.; Melchers, W.J.G.

    2011-01-01

    The clinically validated high-risk human papillomavirus (hrHPV) Hybrid Capture 2 (HC2) and GP5+/6+-PCR assays were analyzed on an Indicating FTA Elute cartridge (FTA cartridge). The FTA cartridge is a solid dry carrier that allows safe transport of cervical samples. FTA cartridge samples were

  8. Characterization of un-irradiated MIMAS MOX fuel by Raman spectroscopy and EPMA

    Science.gov (United States)

    Talip, Zeynep; Peuget, Sylvain; Magnin, Magali; Tribet, Magaly; Valot, Christophe; Vauchy, Romain; Jégou, Christophe

    2018-02-01

    In this study, Raman spectroscopy technique was implemented to characterize un-irradiated MIMAS (MIcronized - MASter blend) MOX fuel samples with average 7 wt.% Pu content and different damage levels, 13 years after fabrication, one year after thermal recovery and soon after annealing, respectively. The impacts of local Pu content, deviation from stoichiometry and self-radiation damage on Raman spectrum of the studied MIMAS MOX samples were assessed. MIMAS MOX fuel has three different phases Pu-rich agglomerate, coating phase and uranium matrix. In order to distinguish these phases, Raman results were associated with Pu content measurements performed by Electron Microprobe Analysis. Raman results show that T2g frequency significantly shifts from 445 to 453 cm-1 for Pu contents increasing from 0.2 to 25 wt.%. These data are satisfactorily consistent with the calculations obtained with Gruneisen parameters. It was concluded that the position of the T2g band is mainly controlled by Pu content and self-radiation damage. Deviation from stoichiometry does not have a significant influence on T2g band position. Self-radiation damage leads to a shift of T2g band towards lower frequency (∼1-2 cm-1 for the UO2 matrix of damaged sample). However, this shift is difficult to quantify for the coating phase and Pu agglomerates given the dispersion of high Pu concentrations. In addition, 525 cm-1 band, which was attributed to sub-stoichiometric structural defects, is presented for the first time for the self-radiation damaged MOX sample. Thanks to the different oxidation resistance of each phase, it was shown that laser induced oxidation could be alternatively used to identify the phases. It is demonstrated that micro-Raman spectroscopy is an efficient technique for the characterization of heterogeneous MOX samples, due to its low spatial resolution.

  9. Induction of lethal mutations in the x-chromosome of unirradiated Drosophila oocytes after fertilization by irradiated spermatozoa

    International Nuclear Information System (INIS)

    Shaposhnikov, M.V.; Zainullin, V.G.

    2003-01-01

    Full text: In primary study on Drosophila it was found that irradiated male X-chromosomes induce recessive lethals in unirradiated female homologues (Abeleva et al., 1961, Radiobiologya. 1:123-126). The same effects were obtained in Drosophila in some recent investigations. The mechanisms of these effects is unknown. However it may be responsible for low-dose radiation effects as it induce mutations in unirradiated DNA. We assume that this effect may be a result of activation of error prone repair in response to preliminary DNA lesions in irradiated chromosome. In this research we analyse the frequencies of the recessive lethal mutations in the X-chromosome of Drosophila females mated with irradiated Basc males. We used acute irradiation with a dose rate of 10 Gy. For testing our hypothesis we use the mus209 and mei-41 mutant females. Mus209 is a PCNA gene homologue and mei-41 is a homologue of ATM gene. These genes are involved in post-replication DNA repair which may be error prone repair in Drosophila. It was obtained the tendency to decreasing the mutation rate at the mei-41[D5] background and decreasing mutation rate in mus209[B1] background in comparison with wild type strains CS (p<0.05). The obtained results demonstrate the possible role of mus209[B1] and mei-41[D5] genes in the inducing of mutations in the unirradiated X-chromosome in the presence of irradiated homologue

  10. Investigation of effective forensic cleaning methods for bullet and cartridge case samples

    Science.gov (United States)

    Shuherk, Cassie Marie

    Bullet and cartridge case evidence may potentially link weapons and crimes through the comparison of toolmark patterns. This analysis relies on the clarity of the toolmarks and the ability of the examiner to identify patterns on the evidence. These patterns may be distorted by debris such as soil, blood, cyanoacrylate, and construction materials. Despite the potential importance of bullet and cartridge case evidence, few investigations of proper cleaning methods have been conducted. The present study was designed to examine the effects of various cleaning solutions and application methods on copper and brass bullets and cartridge cases. Additionally, this research investigated the efficacy of these cleaning protocols on the common evidence contaminants blood and cyanoacrylate. No cleaning method was found to be universally effective on both contaminant types and nondestructive to the metal surface. Ultrasonication was the most efficient application method employed when used in conjunction with an appropriate cleaning solution. Acetone proved to be safe and successful at removing heavy cyanoacrylate deposits from brass cartridge cases without damaging the metal. Although sulfuric acid removed most of the cyanoacrylate from the brass cartridge case, ultrasonication of the fumed cartridge cases in sulfuric acid caused the nickel-plated primer caps to turn black. Additionally, etching occurred when sulfuric acid was allowed to dry on the cartridge case surface. Citric acid, salt-flour-vinegar paste, TergazymeRTM, and water did not effectively remove the cyanoacrylate from the cartridge cases, but the solutions were safe to use on the brass and sometimes resulted in a shinier surface. Regardless of the cleaning method employed, the bloodstained bullets retained most or all of the underlying brown tarnish. Ultrasonication with sulfuric acid was successful at removing some blood-initiated tarnishing; however, the removal of residues was not complete, making it difficult

  11. Comparison of ring compression testing to three point bend testing for unirradiated ZIRLO cladding

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2015-04-01

    Safe shipment and storage of nuclear reactor discharged fuel requires an understanding of how the fuel may perform under the various conditions that can be encountered. One specific focus of concern is performance during a shipment drop accident. Tests at Savannah River National Laboratory (SRNL) are being performed to characterize the properties of fuel clad relative to a mechanical accident condition such as a container drop. Unirradiated ZIRLO tubing samples have been charged with a range of hydride levels to simulate actual fuel rod levels. Samples of the hydrogen charged tubes were exposed to a radial hydride growth treatment (RHGT) consisting of heating to 400°C, applying initial hoop stresses of 90 to 170 MPa with controlled cooling and producing hydride precipitates. Initial samples have been tested using both a) ring compression test (RCT) which is shown to be sensitive to radial hydride and b) three-point bend tests which are less sensitive to radial hydride effects. Hydrides are generated in Zirconium based fuel cladding as a result of coolant (water) oxidation of the clad, hydrogen release, and a portion of the released (nascent) hydrogen absorbed into the clad and eventually exceeding the hydrogen solubility limit. The orientation of the hydrides relative to the subsequent normal and accident strains has a significant impact on the failure susceptability. In this study the impacts of stress, temperature and hydrogen levels are evaluated in reference to the propensity for hydride reorientation from the circumferential to the radial orientation. In addition the effects of radial hydrides on the Quasi Ductile Brittle Transition Temperature (DBTT) were measured. The results suggest that a) the severity of the radial hydride impact is related to the hydrogen level-peak temperature combination (for example at a peak drying temperature of 400°C; 800 PPM hydrogen has less of an impact/ less radial hydride fraction than 200 PPM hydrogen for the same thermal

  12. A study on density, porosity and grain size of unirradiated ROX fuels and simulated ROX fuels

    International Nuclear Information System (INIS)

    Yanagisawa, Kazuaki; Shirasu, Noriko; Ohmichi, Toshihiko

    1999-05-01

    The unirradiated ROX fuels made of (1) 23wt%PuO 2 -17wt%SZR-56wt%Al 2 O 3 -4wt%MgO (ROX-SZR) and (2) 20wt%PuO 2 -29wt%ThO 2 -48wt%Al 2 O 3 -3wt%MgO (ROX-ThO 2 ) were fabricated by JAERI. Additionally, 9 simulated ROX fuels (used UO 2 instead of PuO 2 ) were fabricated by NFI. Densities, porosity and grain sizes of those were studied. Obtained results are: (1) ROX fuels: The estimated theoretical density (TD) was 5.6g/cc for the ROX-SZR and 6.2g/cc for the ROX-ThO 2 . Those were about half of that in UO 2 (10.96g/cc). As-fabricated density determined was 4.6g/cc (82%TD) for the former and 5.2g/cc (83%TD) for the latter. The %TD of those was low than that of UO 2 (95%TD). One of main reason is that the ROX fuels were sintered at temperature of 1,400degC while UO 2 was sintered at temperature of 1,700degC. The average pore diameter was about 3 μm and the porosity was 17-18%, implying that the ROX fuels were resulted in containing a lot of small pores 2 . As-fabricated density determined in the present study was about 4.5-5.5g/cc. The %TD of the simulated ROX fuels ranged about 94-98%TD. They were in the same as that of UO 2 because as high sintering temperature of 1,750degC as UO 2 . The average pore diameter was about 4-8 μm and the porosity was <6%. Grain size was revealed to be about 1-4 μm. (author)

  13. Precession electron diffraction for SiC grain boundary characterization in unirradiated TRISO fuel

    International Nuclear Information System (INIS)

    Lillo, T.M.; Rooyen, I.J. van; Wu, Y.Q.

    2016-01-01

    Highlights: • SiC grain orientation determined by TEM-based precession electron diffraction. • Orientation data improved with increasing TEM sample thickness. • Fraction of low angle grain boundaries lower from PED data than EBSD data. • Fractions of high angle and CSL-related boundaries similar to EBSD data. - Abstract: Precession electron diffraction (PED), a transmission electron microscopy-based technique, has been evaluated for the suitability for evaluating grain boundary character in the SiC layer of tristructural isotropic (TRISO) fuel. This work reports the effect of transmission electron microscope (TEM) lamella thickness on the quality of data and establishes a baseline comparison to SiC grain boundary characteristics, in an unirradiated TRISO particle, determined previously using a conventional electron backscatter diffraction (EBSD) scanning electron microscope (SEM)-based technique. In general, it was determined that the lamella thickness produced using the standard focused ion beam (FIB) fabrication process (∼80 nm), is sufficient to provide reliable PED measurements, although thicker lamellae (∼120 nm) were found to produce higher quality orientation data. Also, analysis of SiC grain boundary character from the TEM-based PED data showed a much lower fraction of low-angle grain boundaries compared to SEM-based EBSD data from the SiC layer of a TRISO-coated particle made using the same fabrication parameters and a SiC layer deposited at a slightly lower temperature from a surrogate TRISO particle. However, the fractions of high-angle and coincident site lattice (CSL)-related grain boundaries determined by PED are similar to those found using SEM-based EBSD. Since the grain size of the SiC layer of TRSIO fuel can be as small as 250 nm (Kirchhofer et al., 2013), depending on the fabrication parameters, and since grain boundary fission product precipitates in irradiated TRISO fuel can be nano-sized, the TEM-based PED orientation data

  14. A self-contained fully-enclosed microfluidic cartridge for lab on a chip.

    Science.gov (United States)

    Yobas, Levent; Cheow, Lih Feng; Tang, Kum-Cheong; Yong, Shien-Eit; Ong, Eleana Kye-Zheng; Wong, Lionel; Teo, William Cheng-Yong; Ji, Hongmiao; Rafeah, Siti; Yu, Chen

    2009-12-01

    We describe a self-contained fully-enclosed cartridge for lab-on-a-chip applications where sample and reagents can be applied sequentially as is performed in a heterogeneous immunoassay, or nucleic acid extraction. Both the self-contained and fully-enclosed features of the cartridge are sought to ensure its safe use in the field by unskilled staff. Simplicity in cartridge design and operation is obtained via adopting a valveless concept whereby reagents are stored and used in the form of liquid plugs isolated by air spacers around a fluidic loop. Functional components integrated in the loop include a microfluidic chip specific to the target application, a novel peristaltic pump to displace the liquid plugs, and a pair of removable tubing segments where one is used to introduce biological sample and while the other is to collect eluant. The novel pump is fabricated through soft-lithography technique and works by pinching a planar channel under stainless-steel ball bearings that have been magnetically loaded. The utility of the cartridge is demonstrated for automated extraction and purification of nucleic acids (DNA) from a cell lysate on a battery-operated portable system. The cartridge shown here can be further extended to sample-in-answer-out diagnostic tests.

  15. Microfluidic cartridges for DNA purification and genotyping processed in standard laboratory instruments

    Science.gov (United States)

    Focke, Maximilian; Mark, Daniel; Stumpf, Fabian; Müller, Martina; Roth, Günter; Zengerle, Roland; von Stetten, Felix

    2011-06-01

    Two microfluidic cartridges intended for upgrading standard laboratory instruments with automated liquid handling capability by use of centrifugal forces are presented. The first microfluidic cartridge enables purification of DNA from human whole blood and is operated in a standard laboratory centrifuge. The second microfluidic catridge enables genotyping of pathogens by geometrically multiplexed real-time PCR. It is operated in a slightly modified off-the-shelf thermal cycler. Both solutions aim at smart and cost-efficient ways to automate work flows in laboratories. The DNA purification cartridge automates all liquid handling steps starting from a lysed blood sample to PCR ready DNA. The cartridge contains two manually crushable glass ampoules with liquid reagents. The DNA yield extracted from a 32 μl blood sample is 192 +/- 30 ng which corresponds to 53 +/- 8% of a reference extraction. The genotyping cartridge is applied to analyse isolates of the multi-resistant Staphyloccus aureus (MRSA) by real-time PCR. The wells contain pre-stored dry reagents such as primers and probes. Evaluation of the system with 44 genotyping assays showed a 100% specificity and agreement with the reference assays in standard tubes. The lower limit of detection was well below 10 copies of DNA per reaction.

  16. Batch fabrication of polymer microfluidic cartridges for QCM sensor packaging by direct bonding

    Science.gov (United States)

    Sandström, Niklas; Zandi Shafagh, Reza; Gylfason, Kristinn B.; Haraldsson, Tommy; van der Wijngaart, Wouter

    2017-12-01

    Quartz crystal microbalance (QCM) sensing is an established technique commonly used in laboratory based life-science applications. However, the relatively complex, multi-part design and multi-step fabrication and assembly of state-of-the-art QCM cartridges make them unsuited for disposable applications such as point-of-care (PoC) diagnostics. In this work, we present the uncomplicated manufacturing of QCMs in polymer microfluidic cartridges. Our novel approach comprises two key innovations: the batch reaction injection molding of microfluidic parts; and the integration of the cartridge components by direct, unassisted bonding. We demonstrate molding of batches of 12 off-stoichiometry thiol-ene epoxy polymer (OSTE+) polymer parts in a single molding cycle using an adapted reaction injection molding process; and the direct bonding of the OSTE+  parts to other OSTE+  substrates, to printed circuit boards, and to QCMs. The microfluidic QCM OSTE+  cartridges were successfully evaluated in terms of liquid sealing as well as electrical properties, and the sensor performance characteristics are on par with those of a commercially available QCM biosensor cartridge. The simplified manufacturing of QCM sensors with maintained performance potentializes novel application areas, e.g. as disposable devices in a point of care setting. Moreover, our results can be extended to simplifying the fabrication of other microfluidic devices with multiple heterogeneously integrated components.

  17. Hazard classification test of the cartridge, 120-mm, APFSDS-T, XM829

    Energy Technology Data Exchange (ETDEWEB)

    Hooker, C.D.; Hadlock, D.E.; Mishima, J.; Gilchrist, R.L.

    1983-11-01

    Research was conducted to determine the behavior of the ammunition XM829 when subjected to detonation of an adjacent XM829 cartridge, and a sustained hot fire. It was concluded that the functioning of an XM829 cartridge, in one shipping container, will not cause immediate functioning of XM829 cartridges in adjacent containers. However, if a fire results and is sustained, adjacent cartridges may ignite, resulting in some scattering of debris within a maximum radius of 40 feet. Further, the XM829 cartridge can be expected to remain in a kinetic controlled regime with vigorous oxidation occurring early in such a fire but dropping off as the temperature cools toward ambient. Mass balance analyses data indicated a recovery of at least 80% in the 1982 external heat; in the 1983 test, the recovery percentage was improved to approximately 100% of the original depleted uranium weight volume. Therefore, it may be concluded that a significant airborne release of the depleted uranium material did not occur.

  18. The isolation of water-soluble radionuclides from deteriorating spent nuclear fuel in zeolite cartridge

    International Nuclear Information System (INIS)

    Hassan, N.M.; Thompson, M.C.

    1996-01-01

    A method of isolating water-soluble radionuclides leaching from deteriorating spent nuclear fuel by ion-exchange in zeolite cartridges has been studied. Design calculations of two zeolite cartridges to be incorporated in typical spent fuel storage bundle have been provided. Equilibrium exchange data obtained at several temperatures have shown that the maximum exchange capacity of total cesium in sodium titanium aluminosilicate was 114 mg/g zeolite and the capacity at 95% exchange for radioactive isotope Cs-137 was calculated as 55.2 mg/g zeolite. The kinetic data suggest that the rate of exchange of Cs + in sodium titanium aluminosilicate zeolite takes place by a fast initial exchange step followed by slow diffusion of cesium cations. Design calculations based on the equilibrium exchange data show that water-soluble radionuclides leaching from Mk 31 slugs can be isolated using two zeolite cartridges, each 3.7 inches in inside diameter and 2.5 inches in length. The cartridges are designed to isolate 95% of the Cs + leaching from the spent fuel storage bundle. The results from the thermal induced convective flow tests indicate that the system will provide necessary cooling to the spent fuel by convective currents while isolating the Cs + leaching from spent fuel storage bundle in the cartridges

  19. Determining Service Life of Respirator Cartridges Using a Simple and Practical Method: Case Study in a Car Manufacturing Industry

    Directory of Open Access Journals (Sweden)

    A.M Rashidi

    2012-01-01

    Full Text Available Background and aims: For ensuring about proper performance of air-purifying respirators in providing protection against workplace contaminants, it is necessary to change the respirator cartridges before the end of their service life. The aim of this study was determination of service life of organic vapor cartridges using a simple and practical method in a spray painting booth of a car manufacturing industry.   Methods: NIOSH MultiVapor software was used for estimating service life of respirator cartridges based on workplace conditions and cartridge specifications. Efficiency of determined service life was investigated using an apparatus for field testing of cartridges in the workplace.   Results: The results showed that existing schedule for changing the respirator cartridges is not effective and no longer provide adequate protection for sprayers against organic contaminants while working in a painting booth. It is necessary to change the cartridges before their estimated service life (every 4 hours.   Conclusion: NIOSH MultiVapor has acceptable efficiency for determining respirator cartridges service life and could be used as a simple and practical method in the workplace. Moreover, Service life estimated by this software was confirmed by cartridge field test apparatus.

  20. Validation of a cartridge method for the quality control determination of 99Tcm-HMPAO

    International Nuclear Information System (INIS)

    Pandos, G.; Penglis, S.; Tsopelas, C.; Royal Adelaide Hospital, Adelaide, SA

    1999-01-01

    Full text: The manufacturer's method for assessing the radiochemical purity (RCP) of ±-HMPAO requires the use of three solvent types on two different stationary phases, and is time-consuming (∼ 15 min) in consideration of the short shelf-life (30 min). An impetus to develop a rapid quality control procedure for this product has led to the use of a single strip Whatman 17 chromatography system using ethyl acetate as the developing solvent. This popular Whatman paper system was previously validates against the manufacturer's method. We have developed a new method to successfully determine the % RCP of ±-HMPAO, which employs a disposable, inexpensive and reusable Amprep C-18 cartridge with normal saline as a non-organic mobile phase. The Whatman paper system separates the primary lipophilic 99 Tc m -HMPAO complex from 99 Tc m O-2, 99 Tc m O 4 and secondary 99 Tc m -HMPAO complex at the origin. By comparison, the lipophilic portion was retained on the cartridge and the hydrophilic impurities were found in saline eluent with the cartridge method. Whatman 17 paper system results showed 95.1 ± I.7% 99 Tc m -HMPAO after 5 min and the cartridge method gave 95.5 ± 1.5% 99 Tc m -HMPAO (n = 8) after 3 min. The % 99 Tc m O 2 levels in 99 Tc m -HMPAO were insignificant. When a failed kit was assessed for RCP at 2.5 h post-reconstitution, the Whatman paper system and the cartridge method correlated well, resulting in 63.1 ± 2.7% and 62.9±2.1% 99 Tc m -HMPAO (n=3) respectively. Although the cartridge method may slightly overestimate the % RCP of 99 Tc m -HMPAO, it was found to be simple, rapid and reliable for the quality control analysis of routine 99 Tc m -HMPAO preparations

  1. Dissolution of unirradiated UO{sub 2} fuel in synthetic groundwater. Final report (1996-1998)

    Energy Technology Data Exchange (ETDEWEB)

    Ollila, K. [VTT Chemical Technology, Espoo (Finland)

    1999-05-01

    This study was a part of the EU R and D programme 1994-1998: Nuclear Fission Safety, entitled `Source term for performance assessment of spent fuel as a waste form`. The research carried out at VTT Chemical Technology was focused on the effects of granitic groundwater composition and redox conditions on UO{sub 2} solubility and dissolution mechanisms. The synthetic groundwater compositions simulated deep granitic fresh and saline groundwaters, and the effects of the near-field material, bentonite, on very saline groundwater. Additionally, the Spanish granite/bentonite water was used. The redox conditions (Eh), which are obviously the most important factors that influence on UO{sub 2} solubility under the disposal conditions of spent fuel, varied from strongly oxidising (air-saturated), anaerobic (N{sub 2}, O{sub 2} < l ppm) to reducing (N{sub 2}, low Eh). The objective of the air-saturated dissolution experiments was to yield the maximum solution concentrations of U, and information on the formation of secondary phases that control the concentrations, with different groundwater compositions. The static batch solubility experiments of long duration (up to 1-2 years) were performed using unirradiated UO{sub 2} pellets and powder. Under anaerobic and reducing conditions, the solubilities were also approached from oversaturation. The results of the oxic, air-saturated dissolution experiments with UO{sub 2} powder showed that the increase in the salinity (< 1.7 M) had a minor effect on the measured steady-state concentrations of U. The concentrations, (1.2 ...2.5) x 10{sup -5} M, were at the level of the theoretical solubility of schoepite or another uranyl oxide hydrate, e.g. becquerelite (possibly Na-polyuranate). The higher alkalinity of the fresh (Allard) composition increased the aqueous U concentration. Only some kind of oxidised U-phase (U{sub 3}O{sub 8}-UO{sub 3}) was identified with XRD when studying possible secondary phases after the contact time of one year

  2. New method to calculate the mechanical properties of unirradiated fuel cladding from ring tensile tests

    Energy Technology Data Exchange (ETDEWEB)

    Martin-Rengel, M.A. [Departamento de Ciencia de Materiales, UPM, E.T.S.I. Caminos, Canales y Puertos, Profesor Aranguren s/n, E-28040 Madrid (Spain); Consejo de Seguridad Nuclear (CSN), Justo Dorado 11, E-28040 Madrid (Spain); Gomez, F.J.; Ruiz-Hervias, J.; Caballero, L.; Valiente, A. [Departamento de Ciencia de Materiales, UPM, E.T.S.I. Caminos, Canales y Puertos, Profesor Aranguren s/n, E-28040 Madrid (Spain)

    2009-06-15

    displacement of the loading piece and another one between the equivalent stress in the same point and the nominal applied stress. In the first iteration a calculation is performed with an approximate plastic stress-strain law, and the two above-mentioned relationships are used to determine a new law from the experimental results. In the second iteration the calculation takes into account the new plastic stress-strain law and determines two new relationships. After a few iterations an excellent fit is obtained. This method is an improvement of the original method by Arsene and Bai [3] and allows obtaining the plastic stress-strain curve in the hoop direction in a consistent way. The experimental data used in this work to check the validity of the procedure have been obtained on unirradiated Zirlo cladding, with the standard alloy composition and geometry (outer diameter of the cladding 9.5 mm and a wall thickness of 0.56 mm). References: [1]. Arsene, S.; Bai, J.B. A new approach to measuring transverse properties of structural tubing by a ring test, Journal of Testing and Evaluation, 24: 386-391 (1996) [2]. Arsene, S.; Bai, J. 'A new approach to measuring transverse properties of structural tubing by a ring test-experimental investigation', Journal of Testing and Evaluation, 26: 26-30 (1998) [3]. Arsene, S.; Bai, J.B.; 'Hydride embrittlement and irradiation effects on the hoop mechanical properties of pressurized water reactor (PWR) and boiling-water reactor (BWR) zircaloy cladding tubes: Part I. Hydride embrittlement in stress-relieved, annealed, and recrystallized zircaloys at 20 deg. C and 300 deg. C', Metallurgical and materials and transactions A, 34A: 553-566 (2003) [4]. Chang-Sun Seok, Bong-Kook, K.Linga, 'The properties of the ring and burst creep of zirlo claddings', Engineering Failure Analysis, 13: 389-397 (2006). (authors)

  3. Dissolution of unirradiated UO2 fuel in synthetic groundwater. Final report (1996-1998)

    International Nuclear Information System (INIS)

    Ollila, K.

    1999-05-01

    This study was a part of the EU R and D programme 1994-1998: Nuclear Fission Safety, entitled 'Source term for performance assessment of spent fuel as a waste form'. The research carried out at VTT Chemical Technology was focused on the effects of granitic groundwater composition and redox conditions on UO 2 solubility and dissolution mechanisms. The synthetic groundwater compositions simulated deep granitic fresh and saline groundwaters, and the effects of the near-field material, bentonite, on very saline groundwater. Additionally, the Spanish granite/bentonite water was used. The redox conditions (Eh), which are obviously the most important factors that influence on UO 2 solubility under the disposal conditions of spent fuel, varied from strongly oxidising (air-saturated), anaerobic (N 2 , O 2 2 , low Eh). The objective of the air-saturated dissolution experiments was to yield the maximum solution concentrations of U, and information on the formation of secondary phases that control the concentrations, with different groundwater compositions. The static batch solubility experiments of long duration (up to 1-2 years) were performed using unirradiated UO 2 pellets and powder. Under anaerobic and reducing conditions, the solubilities were also approached from oversaturation. The results of the oxic, air-saturated dissolution experiments with UO 2 powder showed that the increase in the salinity ( -5 M, were at the level of the theoretical solubility of schoepite or another uranyl oxide hydrate, e.g. becquerelite (possibly Na-polyuranate). The higher alkalinity of the fresh (Allard) composition increased the aqueous U concentration. Only some kind of oxidised U-phase (U 3 O 8 -UO 3 ) was identified with XRD when studying possible secondary phases after the contact time of one year with all groundwater compositions. Longer contact times are needed to identify secondary phases predicted by modelling (EQ3/6). In the anoxic dissolution experiments with UO 2 pellets, the

  4. Interaction of spermine with DNA, vitamin C and bovine serum albumin in the unirradiated and gamma irradiated states

    International Nuclear Information System (INIS)

    Upadhyay, S.N.; Lal, C.; Bhardwaj, R.; Chaturvedi, S.; Chaudhury, N.K.

    2006-01-01

    Structural deformability of spermine with radiation dose (maximum 10 Gy) has been proved. Complex formation of spermine with DNA, vitamin C and BSA took place. Calibration and radiation-induced absorption changes in spermine by ninhydrin reagent has been followed quantitatively. Interaction of vitamin C with DNA and their radiation-induced changes have been reported. Interaction of spermine with DNA in the unirradiated and gamma irradiated states in 10 -3 M phosphate buffer and water have been compared. Addition of spermine and vitamin C to DNA makes DNA structure more condensed. Bovine serum albumin also binds with spermine and protects it from radiation-induced degradation. (author)

  5. Flow sheet development for the dissolution of unirradiated Mark 42 fuel tubes in F-Canyon, Part II

    International Nuclear Information System (INIS)

    Murray, A.M.

    1999-01-01

    Two dissolution flow sheets were tested for the desorption of unirradiated Mark 42 fuel tubes. Both the aluminum (from the can, cladding, and fuel core) and the plutonium oxide (PuO 2 ) are dissolved simultaneously, i.e., a co-dissolution flow sheet. In the first series of tests, 0.15 and 0.20 molar (M) potassium fluoride (KF) solutions were used and the dissolution extended over several days. In the other series of tests, solutions with higher concentrations of fluoride (0.25 to 0.30 M) were used. Calcium fluoride (CaF 2 ) was used in those tests as the fluoride source

  6. Properties of unirradiated fuel element graphites H-451 and SO818. [Bulk density, tensile properties, thermal expansion, thermal conductivity

    Energy Technology Data Exchange (ETDEWEB)

    Engle, G.B.; Johnson, W.R.

    1976-10-08

    Nuclear graphites H-451, lot 440 (Great Lakes Carbon Corporation (GLCC)), and SO818 (Airco Speer Division, Air Reduction Corporation (AS)) are described, and physical, mechanical, and chemical property data are presented for the graphites in the unirradiated state. A summary of the mean values of the property data and of data on TS-1240 and H-451, lot 426, is tabulated. A direct comparison of H-451, lot 426, chosen for Fort St. Vrain (FSV) fuel reload production, TS-1240, and SO818 may be made from the table. (auth)

  7. Application of fire-retardant treatment to the wood in Type A unirradiated nuclear fuel outer containers

    International Nuclear Information System (INIS)

    Whitlow, J.D.; Luna, R.E.

    1992-01-01

    Packagings for transporting unirradiated nuclear fuel assemblies in the United States are commonly constructed as rectangular boxes consisting of a metal inner container, a wooden outer container, and cushioning material separating the two. The wood in the outer container is a potential source of fuel for fire. Use of a fire-retardant treatment on the wood may reduce or eliminate the damage to nuclear fuel assemblies in some types of accidents involving fire. The applicability of using fire-retardant treatments on the wood of outer containers is addressed. An approximate cost-benefit analysis to determine if fire-retardant treatments are economically justified is presented. (Author)

  8. Solubility of unirradiated UO2 fuel in aqueous solutions. Comparison between experimental and calculated (EQ3/6) data

    International Nuclear Information System (INIS)

    Ollila, K.

    1995-11-01

    The solubility behaviour of unirradiated UO 2 pellets was studied under oxic (air-saturated) and anoxic (N 2 ) conditions in deionized water, in sodium bicarbonate solutions with varying bicarbonate content (60 - 600 ppm), in Allard groundwater simulating granitic fresh groundwater conditions, and in bentonite water simulating the effects of bentonite on granitic fresh groundwater (25 deg C). The release of uranium was measured during static batch dissolution experiments of long duration (2-6 years). A comparison was made with the theoretical solubility data calculated with the geochemical code EQ3/6 in order to evaluate solubility (steady state) limiting factors. (orig.) (26 refs., 32 figs., 13 tabs.)

  9. Microfluidic cartridges for automated, point-of-care blood cell counting

    CSIR Research Space (South Africa)

    Smith, Suzanne

    2016-11-01

    Full Text Available Disposable, low-cost microfluidic cartridges for automated blood cell counting applications are presented in this article. The need for point-of-care medical diagnostic tools is evident, particularly in low-resource and rural settings, and a full...

  10. Optimal stapler cartridge selection according to the thickness of the pancreas in distal pancreatectomy.

    Science.gov (United States)

    Kim, Hongbeom; Jang, Jin-Young; Son, Donghee; Lee, Seungyeoun; Han, Youngmin; Shin, Yong Chan; Kim, Jae Ri; Kwon, Wooil; Kim, Sun-Whe

    2016-08-01

    Stapling is a popular method for stump closure in distal pancreatectomy (DP). However, research on which cartridges are suitable for different pancreatic thickness is lacking. To identify the optimal stapler cartridge choice in DP according to pancreatic thickness.From November 2011 to April 2015, data were prospectively collected from 217 consecutive patients who underwent DP with 3-layer endoscopic staple closure in Seoul National University Hospital, Korea. Postoperative pancreatic fistula (POPF) was graded according to International Study Group on Pancreatic Fistula definitions. Staplers were grouped based on closed length (CL) (Group I: CL ≤ 1.5 mm, II: 1.5 mm 17 mm. With pancreatic thickness <12 mm, the POPF rate was lowest with Group II (I: 50%, II: 27.6%, III: 69.2%, P = 0.035).The optimal stapler cartridges with pancreatic thickness <12 mm were those in Group II (Gold, CL: 1.8 mm). There was no suitable cartridge for thicker pancreases. Further studies are necessary to reduce POPF in thick pancreases.

  11. 3D-Printed Paper Spray Ionization Cartridge with Integrated Desolvation Feature and Ion Optics

    NARCIS (Netherlands)

    Salentijn, G Ij; Oleschuk, R D; Verpoorte, E

    2017-01-01

    In this work we present the application of 3D-printing for the miniaturization and functionalization of an ion source for (portable) mass spectrometry (MS). Two versions of a 3D-printed cartridge for paper spray ionization (PSI) are demonstrated, assessed, and compared. We first focus on the use of

  12. Rapid monitoring particulate radiocesium with nonwoven fabric cartridge filter and application to field monitoring

    International Nuclear Information System (INIS)

    Tsuji, Hideki; Yasutaka, Tetsuo; Kondo, Yoshihiko; Kawashima, Shoji

    2013-01-01

    A method for rapid monitoring particulate radiocesium using a nonwoven fabric cartridge filter was developed, which needs no further preprocessing before served to a detector. By a performance test, more than 98% of suspended solid (SS) was collected. This method showed the same radioactivity measurement accuracy as filtration by membrane filter and more rapid extraction capability of SS. (author)

  13. Simplified quality control of radioactive seeds in sterile cartridge for prostate brachytherapy using an imaging plate and a collimator

    International Nuclear Information System (INIS)

    Saze, T.; Miyoshi, H.; Maezawa, H.; Kubota, M.; Furutani, S.; Nishitani, H.; Kawaguchi, Y.; Nakayama, S.; Ito, S.; Nishizawa, K.

    2008-01-01

    Image analyzer system and collimator has been successfully applied to calibrate simultaneously multiple 125 I seeds in a sterile cartridge. Seeds within the cartridge were placed on an imaging plate, and the imaging plate irradiated. To remove scatter radiation, and improve spatial resolution of seed images, this study used a specially designed collimator. The irradiated imaging plate was scanned using an image analyzer system, and radioactivity intensities of seed images were given in counts. Counts could be translated to profiles, and each seed within the cartridge was analyzed. It is observed that a good correlation between counts and total radioactivity of the seeds within the cartridge. Thus, using a least-squares line, it was possible to calibrate a seed with unknown apparent activity. By analyzing the profiles, it was possible not only to detect a mis calibrated seed in the cartridge from its relative difference in counts, but also to identify its position in the cartridge. Using an imaging analyzer system, all seeds in a cartridge could be calibrated in a sterile environment. (author)

  14. Special Analysis for the Disposal of the INL Waste Associated with the Unirradiated Light Water Breeder Reactor (LWBR) Waste Stream at the Area 5 Radioactive Waste Management Site

    Energy Technology Data Exchange (ETDEWEB)

    Shott, Gregory [National Security Technologies, LLC, Las Vegas, NV (United States)

    2017-03-21

    This special analysis (SA) evaluates whether the Idaho National Laboratory (INL) Waste Associated with the Unirradiated Light Water Breeder Reactor (LWBR) waste stream (INEL167203QR1, Revision 0) is suitable for shallow land burial (SLB) at the Area 5 Radioactive Waste Management Site (RWMS) on the Nevada National Security Site (NNSS). Disposal of the INL Waste Associated with the Unirradiated LWBR waste meets all U.S. Department of Energy (DOE) Manual DOE M 435.1-1, “Radioactive Waste Management Manual,” Chapter IV, Section P performance objectives (DOE 1999). The INL Waste Associated with the Unirradiated LWBR waste stream is recommended for acceptance with the condition that the total uranium-233 (233U) inventory be limited to 2.7E13 Bq (7.2E2 Ci).

  15. Lift-based up-ender and methods using same to manipulate a shipping container containing unirradiated nuclear fuel

    Science.gov (United States)

    Nilles, Michael J.

    2017-08-01

    A shipping container containing an unirradiated nuclear fuel assembly is lifted off the ground by operating a crane to raise a lifting tool comprising a winch. The lifting tool is connected with the shipping container by a rigging line connecting with the shipping container at a lifting point located on the shipping container between the top and bottom of the shipping container, and by winch cabling connecting with the shipping container at the top of the shipping container. The shipping container is reoriented by operating the winch to adjust the length of the winch cabling so as to rotate the shipping container about the lifting point. Shortening the winch cabling rotates the shipping container about the lifting point from a horizontal orientation to a vertical orientation, while lengthening the winch cabling rotates the shipping container about the lifting point from the vertical orientation to the horizontal orientation.

  16. Storage for the Fast Flux Test Facility unirradiated fuel in the Plutonium Finishing Plant Complex, Hanford Site, Richland, Washington

    International Nuclear Information System (INIS)

    1992-01-01

    This Environmental Assessment evaluates the proposed action to relocate and store unirradiated Fast Flux Test Facility fuel in the Plutonium Finishing Plant Complex on the Hanford Site, Richland, Washington. The US Department of Energy has decided to cease fuel fabrication activities in the 308 Building in the 300 Area. This decision was based on a safety concern over the ability of the fuel fabrication portion of the 308 Building to withstand a seismic event. The proposed action to relocate and store the fuel is based on the savings that could be realized by consolidating security costs associated with storage of the fuel. While the 308 Building belowgrade fuel storage areas are not at jeopardy by a seismic event, the US Department of Energy is proposing to cease storage operations along with the related fabrication operations. The US Department of Energy proposes to remove the unirradiated fuel pins and fuel assemblies from the 308 Building and store them in Room 192A, within the 234-5Z Building, a part of the Plutonium Finishing Plant Complex, located in the 200 West Area. Minor modifications to Room 192A would be required to accommodate placement of the fuel. The US Department of Energy estimates that removing all of the fuel from the 308 Building would save $6.5 million annually in security expenditures for the Fast Flux Test Facility. Environmental impacts of construction, relocation, and operation of the proposed action and alternatives were evaluated. This evaluation concluded that the proposed action would have no significant impacts on the human environment

  17. Comparison of the growth of Listeria monocytogenes in unirradiated and irradiated cook-chill roast beef and gravy at refrigeration temperatures

    International Nuclear Information System (INIS)

    Grant, I.R.; Nixon, C.R.; Patterson, M.F.

    1993-01-01

    Specific growth rates of two strains of Listeria monocytogenes in unirradiated and irradiated (2 kGy) roast beef and gravy stored at 5° and 10°C were found to be similar. However, exponential growth of L. monocytogenes after irradiation was preceded by an extended lag period of 6–9 d at 5°C and 3–4 d at 10°C, compared with lag periods of 1–2 d and <0.1 d in unirradiated beef and gravy stored similarly

  18. Do insulin cartridges really provide a lower risk of potential diabetes complications than traditional vials?

    Science.gov (United States)

    Al-Sharayri, Mohammad G; Aljbori, Tariq M; Migdadi, Qusai M; Al-Omoush, Marwa B; Jaarah, Ayman R

    2014-09-01

    Recently, many publicly funded healthcare organizations suffered from an economical crisis. This forced some organizations to utilize less costly alternatives where possible. Insulin cartridges and vials are examples. Many patients are questioning the difference between the two alternatives as they contain the same active ingredient. To find out if insulin cartridges really provide a lower risk of potential diabetes complications than traditional vials. A questionnaire was used to ask two random samples of diabetic patients about the development of some diabetes complications. The first sample (n = 41) consisted of patients using cartridges; the second sample (n = 40) consisted of patients using vials. Patients were randomly selected from the endocrine clinic and the out-patient pharmacy in Al-Hussein Hospital in King Hussein Medical Center in Amman- Jordan. 44% of respondents in the first sample did not suffer from any complication; on the other hand, the percentage was only 15% of respondents in the second sample. All respondents (100%) in the first sample suffered from only 2 complications or less; however, 25% of the respondents in the second sample suffered from 3 or more complications. Nephropathy complications, were slightly higher in the first sample; 22% compared to 15% in the second sample. On the other hand, all complications reported in the second sample were higher; 30% for neuropathy, 65% for retinopathy complications and 42.5% for extremities damage compared to only 9.7%, 7.3% and 26.8% respectively in the first sample. In general, respondents who were using cartridges reported a lesser incidence of diabetes complications. Although many organizations suffered from an economical crisis, the cost-effectiveness aspect should be taken into consideration when purchasing medical alternatives. This will provide higher quality of life for patients and eventually lower hidden and future costs for the organizations.

  19. Safety limits of half-mask cartridge respirators for organic solvent vapors

    International Nuclear Information System (INIS)

    Anon.

    1975-01-01

    Recent studies of the effective service life (safety limits) for typical half-mask cartridge respirators have shown these devices to be unsuitable for certain organic vapors, e.g., methanol, methylamine, vinyl chloride, and dichloromethane, because the effective service life is too short. For these vapors other forms of protection such as air-supplied respirators are recommended. The experimentally determined service life for many vapors is shorter--sometimes significantly shorter--than predicted by adsorption theory

  20. Characterization of cartridge filters from the IEA-R1 Nuclear Reactor

    International Nuclear Information System (INIS)

    2015-01-01

    The management of radioactive waste ensures safety to human health and the environment nowadays and for the future, without overwhelming the upcoming generations. The primary characterization of radioactive waste is one of the main steps in the management of radioactive waste. This step permits to choose the best treatment for the radioactive waste before forwarding it to its final disposal. The aim of the present work is the primary characterization of cartridge filters from the IEA-R1 nuclear reactor utilizing gamma-ray spectrometry, and the method of Monte Carlo for calibration. The IEA-R1 is located in the Nuclear and Energy Research Institute (IPEN - CNEN) in the city of Sao Paulo, Brazil. Cartridge filters are used for purification of the cooling water that is pumped through the core of the pool type nuclear research reactors. Once worn out, these filters are replaced and then become radioactive waste. Determination of the radioactive inventory is of paramount importance in the management of such radioactive waste, and one of the main methods for doing so is the gamma-ray spectrometry, which can identify and quantify high energy photon emitters. The technique chosen for the characterization of radioactive waste in the present work is the gamma-ray spectrometry with High purity Germanium (HPGe) detectors. From the energy identified in the experimental spectrum, three radioisotopes were identified in the cartridge filter: 108m Ag, 110m Ag, 60 Co. For the estimated activity of the filter, the calibration in efficiency was made utilizing the MCNP4C code of the Monte Carlo method. Such method was chosen because there is no standard source available in the same geometry of the cartridge filter, therefore a simulation had to be developed in order to reach a calibration equation, necessary to estimate the activity of the radioactive waste. The results presented an activity value in the order of MBq for all radioisotopes. (authors)

  1. Characterization of cartridge filters from the IEA-R1 Nuclear Reactor

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2015-07-01

    The management of radioactive waste ensures safety to human health and the environment nowadays and for the future, without overwhelming the upcoming generations. The primary characterization of radioactive waste is one of the main steps in the management of radioactive waste. This step permits to choose the best treatment for the radioactive waste before forwarding it to its final disposal. The aim of the present work is the primary characterization of cartridge filters from the IEA-R1 nuclear reactor utilizing gamma-ray spectrometry, and the method of Monte Carlo for calibration. The IEA-R1 is located in the Nuclear and Energy Research Institute (IPEN - CNEN) in the city of Sao Paulo, Brazil. Cartridge filters are used for purification of the cooling water that is pumped through the core of the pool type nuclear research reactors. Once worn out, these filters are replaced and then become radioactive waste. Determination of the radioactive inventory is of paramount importance in the management of such radioactive waste, and one of the main methods for doing so is the gamma-ray spectrometry, which can identify and quantify high energy photon emitters. The technique chosen for the characterization of radioactive waste in the present work is the gamma-ray spectrometry with High purity Germanium (HPGe) detectors. From the energy identified in the experimental spectrum, three radioisotopes were identified in the cartridge filter: {sup 108m}Ag, {sup 110m}Ag, {sup 60}Co. For the estimated activity of the filter, the calibration in efficiency was made utilizing the MCNP4C code of the Monte Carlo method. Such method was chosen because there is no standard source available in the same geometry of the cartridge filter, therefore a simulation had to be developed in order to reach a calibration equation, necessary to estimate the activity of the radioactive waste. The results presented an activity value in the order of MBq for all radioisotopes. (authors)

  2. RPA using a multiplexed cartridge for low cost point of care diagnostics in the field.

    Science.gov (United States)

    Ereku, Luck Tosan; Mackay, Ruth E; Craw, Pascal; Naveenathayalan, Angel; Stead, Thomas; Branavan, Manorharanehru; Balachandran, Wamadeva

    2018-04-15

    A point of care device utilising Lab-on-a-Chip technologies that is applicable for biological pathogens was designed, fabricated and tested showing sample in to answer out capabilities. The purpose of the design was to develop a cartridge with the capability to perform nucleic acid extraction and purification from a sample using a chitosan membrane at an acidic pH. Waste was stored within the cartridge with the use of sodium polyacrylate to solidify or gelate the sample in a single chamber. Nucleic acid elution was conducted using the RPA amplification reagents (alkaline pH). Passive valves were used to regulate the fluid flow and a multiplexer was designed to distribute the fluid into six microchambers for amplification reactions. Cartridges were produced using soft lithography of silicone from 3D printed moulds, bonded to glass substrates. The isothermal technique, RPA is employed for amplification. This paper shows the results from two separate experiments: the first using the RPA control nucleic acid, the second showing successful amplification from Chlamydia Trachomatis. Endpoint analysis conducted for the RPA analysis was gel electrophoresis that showed 143 base pair DNA was amplified successfully for positive samples whilst negative samples did not show amplification. End point analysis for Chlamydia Trachomatis samples was fluorescence detection that showed successful detection of 1 copy/μL and 10 copies/μL spiked in a MES buffer. Crown Copyright © 2018. Published by Elsevier Inc. All rights reserved.

  3. Behavioral response and pain perception to computer controlled local anesthetic delivery system and cartridge syringe

    Directory of Open Access Journals (Sweden)

    T D Yogesh Kumar

    2015-01-01

    Full Text Available Aim: The present study evaluated and compared the pain perception, behavioral response, physiological parameters, and the role of topical anesthetic administration during local anesthetic administration with cartridge syringe and computer controlled local anesthetic delivery system (CCLAD. Design: A randomized controlled crossover study was carried out with 120 children aged 7-11 years. They were randomly divided into Group A: Receiving injection with CCLAD during first visit; Group B: Receiving injection with cartridge syringe during first visit. They were further subdivided into three subgroups based on the topical application used: (a 20% benzocaine; (b pressure with cotton applicator; (c no topical application. Pulse rate and blood pressure were recorded before and during injection procedure. Objective evaluation of disruptive behavior and subjective evaluation of pain were done using face legs activity cry consolability scale and modified facial image scale, respectively. The washout period between the two visits was 1-week. Results: Injections with CCLAD produced significantly lesser pain response, disruptive behavior (P < 0.001, and pulse rate (P < 0.05 when compared to cartridge syringe injections. Application of benzocaine produced lesser pain response and disruptive behavior when compared to the other two subgroups, although the result was not significant. Conclusion: Usage of techniques which enhance behavioral response in children like injections with CCLAD can be considered as a possible step toward achieving a pain-free pediatric dental practice.

  4. Motion-Based pH Sensing Based on the Cartridge-Case-like Micromotor.

    Science.gov (United States)

    Su, Yajun; Ge, Ya; Liu, Limei; Zhang, Lina; Liu, Mei; Sun, Yunyu; Zhang, Hui; Dong, Bin

    2016-02-17

    In this paper, we report a novel cartridge-case-like micromotor. The micromotor, which is fabricated by the template synthesis method, consists of a gelatin shell with platinum nanoparticles decorating its inner surface. Intriguingly, the resulting cartridge-case-like structure exhibits a pH-dependent "open and close" feature, which originates from the pH responsiveness of the gelatin material. On the basis of the catalytic activity of the platinum nanoparticle inside the gelatin shell, the resulting cartridge-case-like structure is capable of moving autonomously in the aqueous solution containing the hydrogen peroxide fuel. More interestingly, we find out that the micromotor can be utilized as a motion-based pH sensor over the whole pH range. The moving velocity of the micromotor increases monotonically with the increase of pH of the analyte solution. Three different factors are considered to be responsible for the proportional relation between the motion speed and pH of the analyte solution: the peroxidase-like and oxidase-like catalytic behavior of the platinum nanoparticle at low and high pH, the volumetric decomposition of the hydrogen peroxide under the basic condition and the pH-dependent catalytic activity of the platinum nanoparticle caused by the swelling/deswelling behavior of the gelatin material. The current work highlights the impact of the material properties on the motion behavior of a micromotor, thus paving the way toward its application in the motion-based sensing field.

  5. Change in muzzle velocity due to freezing and water immersion of .22, long rifle, K.F. cartridges.

    Science.gov (United States)

    Jauhari, M; Chatterjee, S M; Ghosh, P K

    1975-01-01

    A study of change in muzzle velocity due to freezing and water immersion of .22, long rifle, K. F. cartridges has been presented. A statistical criterion has been formulated to ascertain whether or not a cartridge undergoes a change in muzzle velocity due to a particular treatment. The muzzle velocity data of .22, long rifle, K. F. cartridges, obtained by an electronic timer before and after the various treatments, have been analyzed in the light of this criterion. These cartridges have generally been found to suffer considerable loss in muzzle velocity when immersed in water for three weeks and also when immersed in water for three days and simultaneously cooled to 0 degrees C. The forensic significance of this loss in muzzle velocity has been discussed.

  6. Radiation quality-dependence of bystander effect in unirradiated fibroblasts is associated with TGF-β1-Smad2 pathway and miR-21 in irradiated keratinocytes

    Science.gov (United States)

    Yin, Xiaoming; Tian, Wenqian; Wang, Longxiao; Wang, Jingdong; Zhang, Shuyu; Cao, Jianping; Yang, Hongying

    2015-01-01

    Traditional radiation biology states that radiation causes damage only in cells traversed by ionizing radiation. But radiation-induced bystander effect (RIBE), which refers to the biological responses in unirradiated cells when the neighboring cells are exposed to radiation, challenged this old dogma and has become a new paradigm of this field. By nature, RIBEs are the consequences of intercellular communication between irradiated and unirradiated cells. However, there are still some important questions remain unanswered such as whether RIBE is dependent on radiation quality, what are the determining factors if so, etc. Using a transwell co-culture system, we found that HaCaT keratinocytes irradiated with α-particles but not X-rays could induce bystander micronucleus formation in unirradiated WS1 fibroblasts after co-culture. More importantly, the activation of TGF-β1-Smad2 pathway and the consistent decrease of miR-21 level in α-irradiated HaCaT cells were essential to the micronucleus induction in bystander WS1 cells. On the other hand, X-irradiation did not induce bystander effect in unirradiated WS1 cells, accompanied by lack of Smad2 activation and consistent decrease of miR-21 in X-irradiated HaCaT cells. Taken together, these results suggest that the radiation quality-dependence of bystander effect may be associated with the TGF-β1-Smad2 pathway and miR-21 in irradiated cells. PMID:26080011

  7. The Analysis of the General Performance and Mechanical Behavior of Unirradiated FeCrAl Alloys Before and After Welding

    Energy Technology Data Exchange (ETDEWEB)

    Gussev, Maxim N. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Field, Kevin G. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Yamamoto, Yukinori [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-06-03

    The present report summarizes and discusses the preliminary results for the in-depth characterization of the modern, nuclear-grade FeCrAl alloys currently under development. The alloys were designed for enhanced radiation tolerance and weldability, and the research is currently being pursued by the Department of Energy (DOE) Nuclear Energy Enabling Technologies (NEET) program. Last year, seven candidate FeCrAl alloys with well-controlled chemistry and microstructures were designed and produced; welding was performed under well-controlled conditions. The structure and general performance of unirradiated alloys were assessed using standardized and advanced microstructural characterization techniques and mechanical testing. The primary objective is to identify the best candidate alloy, or at a minimum to identify the contributing factors that increase the weldability and radiation tolerance of FeCrAl alloys, therefore enabling future generations of FeCrAl alloys to deliver better performance parameters. This report is structured so as to describe these critical assessments of the weldability; radiation tolerance will be reported on in later reports from this program.

  8. Semi-conservative deoxyribonucleic acid synthesis in unirradiated and ultraviolet-irradiated xeroderma pigmentosum and normal human skin fibroblasts

    International Nuclear Information System (INIS)

    Rude, J.M.; Friedberg, E.C.

    1977-01-01

    Rates of semiconservative DNA synthesis have been investigated in asynchronous xeroderma pigmentosum (XP), XP variant, and normal human skin fibroblasts using the technique of cellular autoradiography. In unirradiated cells, no differences in DNA synthesis rates were detected among the three cell strains. Exposure to UV radiation caused the rate of DNA synthesis to decrease for at least three hours in all three cell strains. In the normal cell strain, recovery of the DNA synthetic rate occurred at later times following a UV fluence of 5 J/m 2 . At this same UV fluence, recovery was absent in classical XP cells during a 24 h post-irradiation period while it was slower than normal in XP variant cells. When the UV fluence to classical XP and XP variant cells was reduced so that survival in all three cell strains was approximately the same (25%), recovery of the DNA synthetic rate was similar in all three cell strains. These results are discussed in terms of current models of DNA replication in UV-irradiated cells and indicate: (1) that pyrimidine dimers are very effective blocks to DNA synthesis and (2) that there is no inherent defect in semiconservative DNA synthesis in either classical XP or XP variant cells which is independent of a defect in DNA repair capacity

  9. Study on the behavior of unirradiated light water reactor fuel with iodine-127 under the reactivity initiated accident (RIA) conditions

    International Nuclear Information System (INIS)

    Sasajima, Hideo; Yanagisawa, Kazuaki; Kanazawa, Hiroyuki

    1988-07-01

    In a light water reactor fuel, a stress arised from pellet-cladding interaction (PCI) will have possibility to cause stress corrosion claddling (PCI failure) under an environment of corrosive fission product ; line iodine. A pulse irradiation experiment by NSRR was carried out to examine whether or not an unirradiated NSRR standard fuel rod in which 1.3 mg (33 x 10 -6 g/cm 2 ) of iodine was artificially filled could cause the PCI failure. Obtained results are: (1) The fuel rods with iodine did not fail both at deposited energy levels of 268 and 280 cal/g · UO 2 . On the other hand, the fuel rods without iodine failed at the same energy levels due to thinning of the cladding wall thickness. Within this experimental scope, PCI-failure did not occur on iodine filled fuel rods. (2) At a periphery of the fuel pellet of iodine filled rod, an uniform torus ring was formed. The torus ring consisted of an equi-axed large grains at 268 cal/g · UO 2 and a columnar ones at 280 cal/g · UO 2 . The torus ring was not formed in the fuel without iodine. (author)

  10. Semi-conservative deoxyribonucleic acid synthesis in unirradiated and ultraviolet-irradiated xeroderma pigmentosum and normal human skin fibroblasts

    Energy Technology Data Exchange (ETDEWEB)

    Rude' e, J.M.; Friedberg, E.C.

    1977-03-01

    Rates of semiconservative DNA synthesis have been investigated in asynchronous xeroderma pigmentosum (XP), XP variant, and normal human skin fibroblasts using the technique of cellular autoradiography. In unirradiated cells, no differences in DNA synthesis rates were detected among the three cell strains. Exposure to uv radiation caused the rate of DNA synthesis to decrease for at least three hours in all three cell strains. In the normal cell strain, recovery of the DNA synthetic rate occurred at later times following a uv fluence of 5 J/m2. At this same uv fluence, recovery was absent in classical XP cells during a 24 h post-irradiation period while it was slower than normal in XP variant cells. When the uv fluence to classical XP and XP variant cells was reduced so that survival in all three cell strains was approximately the same (25%), recovery of the DNA synthetic rate was similar in all three cell strains. These results are discussed in terms of current models of DNA replication in uv-irradiated cells and indicate: (1) that pyrimidine dimers are very effective blocks to DNA synthesis and (2) that there is no inherent defect in semi-conservative DNA synthesis in either classical XP or XP variant cells which is independent of a defect in DNA repair capacity.

  11. Tensile and electrical properties of unirradiated and irradiated Hycon 3HP{trademark} CuNiBe

    Energy Technology Data Exchange (ETDEWEB)

    Zinkle, S.J.; Eatherly, W.S. [Oak Ridge National Lab., TN (United States)

    1996-10-01

    The unirradiated tensile properties of two different heats of Hycon 3HP{trademark} CuNiBe (HT Temper) have been measured over the temperature range of 20-500{degrees}C for longitudinal and long transverse orientations. The room temperature electrical conductivity has also been measured for both heats. Both heats exhibited a very good combination of strength and conductivity at room temperature. The strength remained relatively high at all test temperatures, with a yield strength of 420-520 MPa at 500{degrees}C. However, low levels of ductility (<5% uniform elongation) were observed at test temperatures above 200-250{degrees}C, due to flow localization adjacent to grain boundaries. Fission neutron irradiation to a dose of {approximately}0.7 dpa at temperatures between 100 and 240{degrees}C produced a slight increase in strength and a significant decrease in ductility. The measured tensile elongation increased with increasing irradiation temperature, with a uniform elongation of {approximately}3.3% observed at 240{degrees}C. The electrical conductivity decreased slightly following irradiation, due to the presence of defect clusters and Ni, Zn, Co transmutation products. The data indicate that CuNiBe alloys have irradiated tensile and electrical properties comparable or superior to CuCrZr and oxide dispersion strengthened copper at temperatures <250{degrees}C, and may be suitable for certain fusion energy structural applications.

  12. Comparison of toxin production by clostridium botulinum type E in irradiated and unirradiated vacuum-packed trout (Salmo gairdneri)

    International Nuclear Information System (INIS)

    Hussain, M.; Ehlermann, D.; Diehl, J.F.

    1977-01-01

    Trouts obtained from a nearby Fish farm were slaughtered, gutted, cut into 100g samples and inoculated with 10 1 , 10 3 and 10 5 spores per g of Clostridium botulinum type E. The vacuum-packed samples were stored under melting ice (0 0 C) and at temperatures of 5 0 and 10 0 C for periods of up to 8 weeks. At weekly intervals, occurrence of spoilage and toxin production were determined. Only at 10 0 C storage, the irradiated samples showed toxin production before spoilage was observed. When the fishes were stored at 5 0 C, no toxicity occured before spoilage was observed even in samples treated with doses as high as 200 krad. Samples stored under melting ice, irradiated or unirradiated, never showed toxin production. It is concluded that the radurization of fish at doses of about 100 or 200 krad and at storage temperatures of melting ice or up to 5 0 C is safe with regard to a possible botulism risk. (orig.) [de

  13. Comparison of toxin production by clostridium botulinum type E in irradiated and unirradiated vacuum-packed trout (Salmo gairdneri)

    International Nuclear Information System (INIS)

    Hussain, A.M.; Ehlermann, D.; Diehl, J.F.

    1977-01-01

    Trouts obtained from a nearby fish farm were slaughtered, gutted, cut into 100 g samples and inoculated with 10 1 , 10 3 and 10 5 spores per g of Clostridium botulinum type E. The vacuum-packed samples were stored under melting ice (0 0 C) and at temperatures of 5 0 and 10 0 C for periods of up to 8 weeks. At weekly intervals, occurrence of spoilage and toxin production were determined. Only at 10 0 C storage, the irradiated samples showed toxin production before spoilage was observed. When the fishes were stored at 5 0 C, no toxicity occurred before spoilage was observed even in samples treated with doses as high as 200 krad. Samples stored under melting ice, irradiated or unirradiated, never showed toxin production. It is concluded that the radurization of fish at doses of about 100 or 200 krad and at storage temperatures of melting ice or up to 5 0 C is safe with regard to a possible botulism risk. (orig.) [de

  14. Rapid, efficient and selective preconcentration of benzo[a]pyrene (BaP) by molecularly imprinted composite cartridge and HPLC

    Energy Technology Data Exchange (ETDEWEB)

    Çorman, Mehmet Emin, E-mail: mecorman@sinop.edu.tr [Hacettepe University, Department of Chemistry, Ankara (Turkey); Sinop University, Department of Bioengineering, Sinop (Turkey); Armutcu, Canan [Hacettepe University, Department of Chemistry, Ankara (Turkey); Uzun, Lokman, E-mail: lokman@hacettepe.edu.tr [Hacettepe University, Department of Chemistry, Ankara (Turkey); Denizli, Adil [Hacettepe University, Department of Chemistry, Ankara (Turkey)

    2017-01-01

    In this study, cryogel-based molecularly imprinted composite cartridges were designed for the rapid, efficient, and selective preconcentration of benzo[a]pyrene (BaP) from water samples. First, a BaP-imprinted poly(2-hydroxyethyl methacrylate-N-methacryloyl-(L)-phenylalanine) composite cartridge was synthesized under semi-frozen conditions and characterized by scanning electron microscopy, elemental analysis, Fourier transform infrared spectroscopy, and swelling tests. After the optimization of preconcentration parameters, i.e., pH and initial BaP concentration, the selectivity and preconcentration efficiency, and reusability of these cartridges were also evaluated. In selectivity experiments, BaP imprinted composite cartridge exhibited binding capacities 3.09, 9.52, 8.87, and 8.77-fold higher than that of the non-imprinted composite cartridge in the presence of competitors, such as benzo[b]fluoranthene (BbF), benzo[k]fluoranthene (BkF), indeno[1,2,3-cd]pyrene (IcdP), and 1-naphthol, respectively. The method detection limit (MDL), relative standard deviation (RSD) and preconcentration efficiency (PE) of the synthesized composite cartridge were calculated as 24.86 μg/L, 1.60%, and 349.6%, respectively. - Highlights: • Cryogel based molecularly imprinted composite cartridges as solid-phase extraction sorbents • Combination unique structural features of cryogels with MIP • An excellent ability to recognize the BaP molecule even if single-run contact • Rapid, efficient, selective and cost-friendly PAH preconcentration • Hydrophobic interactions via N-methacryloyl-(L)-phenylalanine.

  15. Facilitation of syngeneic stem cell engraftment by anti-class I monoclonal antibody pretreatment of unirradiated recipients

    International Nuclear Information System (INIS)

    Voralia, M.; Semeluk, A.; Wegmann, T.G.

    1987-01-01

    We have established a murine model of syngeneic bone marrow transplantation based on the use of monoclonal antibody as the sole conditioning regimen in unirradiated recipients. Administration of a single injection of monoclonal antibody directed against major histocompatibility complex-encoded class I determinants facilitated permanent hemopoietic stem cell engraftment without any apparent side-effects. Whereas untreated hosts exhibited a maximal chimerism of 15% at donor cell doses of up to 12 X 10(7) bone marrow cells, pretreatment by 2 mg of anti-class I antibody one week prior to transplantation of 3 X 10(7) syngeneic bone marrow cells resulted in a mean donor representation of about 80%. The antibody can be given up to four weeks prior to transplantation, and the degree of donor engraftment observed is a function of the dose of antibody administered. The fact that specific antibody enhanced engraftment in two strain combinations indicates that antibody is the active agent in facilitating engraftment and that facilitation is not strain-restricted. Anti-class I antibodies of the IgG2a, but not IgG1, isotype are effective in promoting engraftment. Although the isotype requirement suggests a role for antibody-mediated cytotoxicity in promoting stem cell engraftment, the extensive time-frame of facilitation suggests that other effects of the antibody may also be involved. The model of syngeneic bone marrow transplantation we describe here will be useful in studying the mechanisms regulating stem cell engraftment and may have potential clinical application as an approach to autologous marrow transplantation

  16. On-cartridge derivatisation using matrix solid phase dispersion for the determination of cyclamate in foods

    International Nuclear Information System (INIS)

    Li, Jianjun; Liu, Yun; Liu, Qianping; Hui, Junfeng; Liu, Yangzi

    2017-01-01

    A novel method for determination of sodium cyclamate in foods was developed. In this method, a syringe was loaded with the homogeneous mixture of the sample, KMnO 4 powder and silica dispersant and used as a matrix solid phase dispersion (MSPD) reactor. As the reactor was infiltrated with small amounts of concentrated HCl, cyclamate was converted to 2-chlorocyclohexanone quickly and effectively within 5 min and determined by HPLC on a reversed-phase column using UV detection at a wavelength of 310 nm. Comparing with the traditional derivatisation in solution, the better clean-up was provided using on-cartridge derivatisation of MSPD, and much time, labor, and expense were saved. The results showed good linearity (r 2  = 0.9998) over the concentration range of 1–500 mg/L. The limit of detection (LOD) and limits of quantification (LOQ) of the cyclamate were 0.3 mg/L and 1 mg/L respectively. The recoveries ranged from 91.6% to 101.3% with the relative standard deviations (RSDs) in the range of 2.5%–4.3%. - Highlights: • A novel method was developed for the determination of cyclamate in foods. • On cartridge derivatisation, using matrix solid phase dispersion, was developed. • A new derivatisation reaction for cyclamate conversion to 2-chlorocyclohexanone was developed. • The method was rapid, simple, inexpensive, effective.

  17. Thermal enhancement cartridge heater modified (TECH Mod) tritium hydride bed development, Part 1 - Design and fabrication

    Energy Technology Data Exchange (ETDEWEB)

    Klein, J.E.; Estochen, E.G. [Savannah River National Laboratory, Aiken, SC (United States)

    2015-03-15

    The Savannah River Site (SRS) tritium facilities have used first generation (Gen1) LaNi{sub 4.25}Al{sub 0.75} (LANA0.75) metal hydride storage beds for tritium absorption, storage, and desorption. The Gen1 design utilizes hot and cold nitrogen supplies to thermally cycle these beds. Second and third generation (Gen2 and Gen3) storage bed designs include heat conducting foam and divider plates to spatially fix the hydride within the bed. For thermal cycling, the Gen2 and Gen3 beds utilize internal electric heaters and glovebox atmosphere flow over the bed inside the bed external jacket for cooling. The currently installed Gen1 beds require replacement due to tritium aging effects on the LANA0.75 material, and cannot be replaced with Gen2 or Gen3 beds due to different designs of these beds. At the end of service life, Gen1 bed desorption efficiencies are limited by the upper temperature of hot nitrogen supply. To increase end-of-life desorption efficiency, the Gen1 bed design was modified, and a Thermal Enhancement Cartridge Heater Modified (TECH Mod) bed was developed. Internal electric cartridge heaters in the new design to improve end-of-life desorption, and also permit in-bed tritium accountability (IBA) calibration measurements to be made without the use of process tritium. Additional enhancements implemented into the TECH Mod design are also discussed. (authors)

  18. On-cartridge derivatisation using matrix solid phase dispersion for the determination of cyclamate in foods

    Energy Technology Data Exchange (ETDEWEB)

    Li, Jianjun, E-mail: bootan12@126.com [Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Northwest University, Xi' an 710069 (China); National Engineering Research Center for Miniaturized Detection Systems, Xi' an 710069 (China); Liu, Yun [College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi' an 710062 (China); Liu, Qianping [National Engineering Research Center for Miniaturized Detection Systems, Xi' an 710069 (China); Hui, Junfeng [Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Northwest University, Xi' an 710069 (China); Liu, Yangzi [National Engineering Research Center for Miniaturized Detection Systems, Xi' an 710069 (China)

    2017-06-15

    A novel method for determination of sodium cyclamate in foods was developed. In this method, a syringe was loaded with the homogeneous mixture of the sample, KMnO{sub 4} powder and silica dispersant and used as a matrix solid phase dispersion (MSPD) reactor. As the reactor was infiltrated with small amounts of concentrated HCl, cyclamate was converted to 2-chlorocyclohexanone quickly and effectively within 5 min and determined by HPLC on a reversed-phase column using UV detection at a wavelength of 310 nm. Comparing with the traditional derivatisation in solution, the better clean-up was provided using on-cartridge derivatisation of MSPD, and much time, labor, and expense were saved. The results showed good linearity (r{sup 2} = 0.9998) over the concentration range of 1–500 mg/L. The limit of detection (LOD) and limits of quantification (LOQ) of the cyclamate were 0.3 mg/L and 1 mg/L respectively. The recoveries ranged from 91.6% to 101.3% with the relative standard deviations (RSDs) in the range of 2.5%–4.3%. - Highlights: • A novel method was developed for the determination of cyclamate in foods. • On cartridge derivatisation, using matrix solid phase dispersion, was developed. • A new derivatisation reaction for cyclamate conversion to 2-chlorocyclohexanone was developed. • The method was rapid, simple, inexpensive, effective.

  19. Hydrogen Car Cartridges: A New Strategy for Hydrogen Storage, Delivering and Refueling

    Energy Technology Data Exchange (ETDEWEB)

    Prosini, Pier Paolo

    2007-07-01

    The purpose of the project is to introduce a sustainable model in the automotive field, guarantying the Kyoto agreements. The aim of the project is to develop an innovative hydrogen tank able to power an hydrogen fuel cell car with the same performance of liquid fuelled cars. Most of the system performance are expected to satisfy the Department of Energy (DOE) goals for 2015. The hydrogen releasing system is based on solid NaBH4 which is hydrolyzed with water or steam to obtain hydrogen. Sodium borate is obtained as by-product and it has to be recycled. Pure and humidified hydrogen, ready to be utilized in a fuel cell, is obtained by a simple and sure way. Hydrogen is produced only when it is requested and therefore there is never pressurized hydrogen or hydrogen overproduction The system works at atmospheric pressure avoiding the problems related to handling and storing pressurized gas. The car fuelling could be performed in area like the present service stations. The used cartridges can be removed and substituted by new cartridges. Contemporarily a water tank should be refilled. To improve the total energetic yield it was also proposed a NaBH4 regeneration process directly starting from the products of hydrolysis. (auth)

  20. Revised ANL-reported tensile data for unirradiated and irradiated (FFTF, HFIR) V-Ti and V-Cr-Ti alloys

    International Nuclear Information System (INIS)

    Billone, M.C.

    1998-01-01

    The tensile data for all unirradiated and irradiated vanadium alloys samples tested at Argonne National Laboratory (ANL) have been critically reviewed and, when necessary, revised. The review and revision are based on reanalyzing the original load-displacement strip chart recordings by a methodology consistent with current ASTM standards. For unirradiated alloys (162 samples), the revised values differ from the previous values as follows: -11±19 MPa (-4±6%) for yield strength (YS), -3±15 MPa (-1±3%) for ultimate tensile strength (UTS), -5±2% strain for uniform elongation (UE), and -4±2% strain for total elongation (TE). Of these changes, the decrease in -1±6 MPa (0±1%) for UTS, -5±2% for UE, and -4±2% for TE. Of these changes, the decrease in UE values for alloys irradiated and tested at 400--435 C is the most significant. This decrease results from the proper subtraction of nongauge-length deformation from measured crosshead deformation. In previous analysis of the tensile curves, the nongauge-length deformation was not correctly determined and subtracted from the crosshead displacement. The previously reported and revised tensile values for unirradiated alloys (20--700 C) are tabulated in Appendix A. The revised tensile values for the FFTF-irradiated (400--600 C) and HFIR-irradiated (400 C) alloys are tabulated in Appendix B, along with the neutron damage and helium levels. Appendix C compares the revised values to the previously reported values for irradiated alloys. Appendix D contains previous and revised values for the tensile properties of unirradiated V-5Cr-5Ti (BL-63) alloy exposed to oxygen

  1. The influence of late-stage pupal irradiation and increased irradiated: un-irradiated male ratio on mating competitiveness of the malaria mosquito Anopheles arabiensis Patton.

    Science.gov (United States)

    Helinski, M E H; Knols, B G J

    2009-06-01

    Competitiveness of released males in genetic control programmes is of critical importance. In this paper, we explored two scenarios to compensate for the loss of mating competitiveness after pupal stage irradiation in males of the malaria mosquito Anopheles arabiensis. First, competition experiments with a higher ratio of irradiated versus un-irradiated males were performed. Second, pupae were irradiated just prior to emergence and male mating competitiveness was determined. Males were irradiated in the pupal stage with a partially or fully-sterilizing dose of 70 or 120 Gy, respectively. Pupae were irradiated aged 20-26 h (young) as routinely performed, or the pupal stage was artificially prolonged by cooling and pupae were irradiated aged 42-48 h (old). Irradiated males competed at a ratio of 3:1:1 to un-irradiated males for mates in a large cage design. At the 3:1 ratio, the number of females inseminated by males irradiated with 70 Gy as young pupae was similar to the number inseminated by un-irradiated males for the majority of the replicates. At 120 Gy, significantly fewer females were inseminated by irradiated than by un-irradiated males. The irradiation of older pupae did not result in a significantly improved male mating competitiveness compared to the irradiation of young pupae. Our findings indicate that the loss of competitiveness after pupal stage irradiation can be compensated for by a threefold increase of irradiated males, but only for the partially-sterilizing dose. In addition, cooling might be a useful tool to facilitate handling processes of large numbers of mosquitoes in genetic control programmes.

  2. Tensile and fracture toughness properties of copper alloys and their HIP joints with austenitic stainless steel in unirradiated and neutron irradiated condition

    International Nuclear Information System (INIS)

    Taehtinen, S.; Pyykkoenen, M.; Singh, B.N.; Toft, P.

    1998-03-01

    The tensile strength and ductility of unirradiated CuAl25 IG0 and CuCrZr alloys decreased continuously with increasing temperature up to 350 deg C. Fracture toughness of unirradiated CuAl25 IG0 alloy decreased continuously with increasing temperature from 20 deg C to 350 deg C whereas the fracture toughness of unirradiated CuCrZr alloy remained almost constant at temperatures up to 100 deg C, was decreased significantly at 200 deg C and slightly increased at 350 deg C. Fracture toughness of HIP joints were lower than that of corresponding copper alloy and fracture path in HIP joint specimen was always within copper alloy side of the joint. Neutron irradiation to a dose level of 0.3 dpa resulted in hardening and reduction in uniform elongation to about 2-4% at 200 deg C in both copper alloys. At higher temperatures softening was observed and uniform elongation increased to about 5% and 16% for CuAl25 IG0 and CuCrZr alloys, respectively. Fracture toughness of CuAl25 IG0 alloy reduced markedly due to neutron irradiation in the temperature range from 20 deg C to 350 deg C. The fracture toughness of the irradiated CuCrZr alloy also decreased in the range from 20 deg C to 350 deg C, although it remained almost unaffected at temperatures below 200 deg C and decreased significantly at 350 deg C when compared with that of unirradiated CuCrZr alloy. (orig.)

  3. Synthesis of O-(2-[18F]fluoroethyl)-L-tyrosine based on a cartridge purification method

    International Nuclear Information System (INIS)

    Mueller, Dirk; Klette, Ingo; Kalb, Fabrizia; Baum, Richard P.

    2011-01-01

    Introduction: O-(2-[ 18 F]fluoroethyl)-L-tyrosine (FET) is widely used as a positron emission tomography tracer for brain tumors. Usually, a high-performance liquid chromatography (HPLC) purification at the end of the two-step synthesis is applied. In this work, we report an automatic radiosynthesis of FET with a purification procedure based on standard cartridges. Methods: O-(2-[ 18 F]fluoroethyl)-L-tyrosine was prepared by [ 18 F]fluoroethylation of L-tyrosine by a two-step synthesis using a modified [ 11 C]methionine module (Nuclear Interface). In the first reaction step, we synthesized [ 18 F]fluoroethyltosylate starting from [ 18 F]fluoride. After a purification step, L-tyrosine was [ 18 F]fluoroethylated with [ 18 F]fluoroethyltosylate. The final reaction mixture was purified by means of solid phase extraction. The FET was trapped on an SCX cartridge, eluted with saline solution and trapped again on an HRX cartridge. For a second purification step, the FET was eluted from the HRX cartridge with ammonium acetate buffer and collected on two SCX cartridges followed by a washing step with water. The final product was eluted with saline solution and neutralised with 450 μl NaHCO 3 solution (8.4%). Results: The synthesis was finished after 50 min and delivered the FET in a range of 3-16 GBq. The synthesis typically yielded 41% (21 experiments) of FET (d.c.) without an HPLC purification step. The radiochemical purity ranged between 97% and 100%. Conclusion: We present a radiosynthesis of FET where the usually used HPLC purification procedure has been substituted by a purification step based on standard cartridges. This method is useful for automatic modules without an expensive HPLC purification unit and for the routine production of FET.

  4. Environmental impacts and resource losses of incinerating misplaced household special wastes (WEEE, batteries, ink cartridges and cables)

    DEFF Research Database (Denmark)

    Bigum, Marianne Kristine Kjærgaard; Damgaard, Anders; Scheutz, Charlotte

    2017-01-01

    The contribution of misplaced special waste (sWEEE, lamps, CRT, batteries, ink cartridges and cables) to environmental impacts from incineration of residual household waste was quantified through life cycle assessment (LCA)-modelling. Misplaced special waste was quantified to constitute less than 1...... and batteries. However as shown by sensitivity analysis, lack of good data on the transfer of rare and hazardous metals to the flue gas in the incineration process should receive further investigation before the environmental impacts from misplaced incinerated special waste can fully be concluded upon. Although...... special waste (sWEEE, lamps, CRT, batteries, ink cartridges, and cables)....

  5. Computer-Aided-Design of the Hydraulic System of Three-Dimensional Cartridge Valve Blocks (Selected Articles)

    Science.gov (United States)

    1991-03-21

    sectional representation of the spatial figure can be correctly determined. 6 The AutoLisp language system in the AutoCAD software provides the most...softwares are developed on the 32-bit machines and little progress has been reported for the 16-bit machines. Even the AutoCAD is a two-ard-a-half... AutoCAD software as the basis, developed the design package of 3-D cartridge valve blocks on IM PC/AT. To realize the 3-D displaying of cartridge valves

  6. Oxide particle size distribution from shearing irradiated and unirradiated LWR fuels in Zircaloy and stainless steel cladding: significance for risk assessment

    Energy Technology Data Exchange (ETDEWEB)

    Davis, W. Jr.; West, G.A.; Stacy, R.G.

    1979-03-22

    Sieve fractionation was performed with oxide particles dislodged during shearing of unirradiated or irradiated fuel bundles or single rods of UO/sub 2/ or 96 to 97% ThO/sub 2/--3 to 4% UO/sub 2/. Analyses of these data by nonlinear least-squares techniques demonstrated that the particle size distribution is lognormal. Variables involved in the numerical analyses include lognormal median size, lognormal standard deviation, and shear cut length. Sieve-fractionation data are presented for unirradiated bundles of stainless-steel-clad or Zircaloy-2-clad UO/sub 2/ or ThO/sub 2/--UO/sub 2/ sheared into lengths from 0.5 to 2.0 in. Data are also presented for irradiated single rods (sheared into lengths of 0.25 to 2.0 in.) of Zircaloy-2-clad UO/sub 2/ from BWRs and of Zircaloy-4-clad UO/sub 2/ from PWRs. Median particle sizes of UO/sub 2/ from shearing irradiated stainless-steel-clad fuel ranged from 103 to 182 ..mu..m; particle sizes of ThO/sub 2/--UO/sub 2/, under these same conditions, ranged from 137 to 202 ..mu..m. Similarly, median particle sizes of UO/sub 2/ from shearing unirradiated Zircaloy-2-clad fuel ranged from 230 to 957 ..mu..m. Irradiation levels of fuels from reactors ranged from 9,000 to 28,000 MWd/MTU. In general, particle sizes from shearing these irradiated fuels are larger than those from the unirradiated fuels; however, unirradiated fuel from vendors was not available for performing comparative shearing experiments. In addition, variations in particle size parameters pertaining to samples of a single vendor varied as much as those between different vendors. The fraction of fuel dislodged from the cladding is nearly proportional to the reciprocal of the shear cut length, until the cut length attains some minimum value below which all fuel is dislodged. Particles of fuel are generally elongated with a long-to-short axis ratio usually less than 3. Using parameters of the lognormal distribution estimates can be made of fractions of dislodged fuel having

  7. Detection and genotyping of human papillomavirus in self-obtained cervicovaginal samples by using the FTA cartridge: new possibilities for cervical cancer screening.

    NARCIS (Netherlands)

    Lenselink, C.H.; Bie, R.P. de; Hamont, D. van; Bakkers, J.M.J.E.; Quint, W.G.V.; Massuger, L.F.A.G.; Bekkers, R.L.M.; Melchers, W.J.G.

    2009-01-01

    This study assesses human papillomavirus (HPV) detection and genotyping in self-sampled genital smears applied to an indicating FTA elute cartridge (FTA cartridge). The study group consisted of 96 women, divided into two sample sets. All samples were analyzed by the HPV SPF(10)-Line Blot 25. Set 1

  8. Disposable cartridge extraction of retinol and alpha-tocopherol from fatty samples.

    Science.gov (United States)

    Bourgeois, C F; Ciba, N

    1988-01-01

    A new approach is proposed for liquid/solid extraction of retinol and alpha-tocopherol from samples, using a disposable kieselguhr cartridge. The substitution of the mixture methanol-ethanol-n-butanol (4 + 3 + 1) for methanol in the alkaline hydrolysis solution makes it now possible to process fatty samples. Methanol is necessary to solubilize the antioxidant ascorbic acid, and a linear chain alcohol such as n-butanol is necessary to reduce the size of soap micelles so that they can penetrate into the kieselguhr pores. In comparisons of the proposed method with conventional methods on mineral premixes and fatty feedstuffs, recovery and accuracy are at least as good by the proposed method. Advantages are increased rate of determinations and the ability to hydrolyze and extract retinol and alpha-tocopherol together from the same sample.

  9. A Modified Electrostatic Adsorption Apparatus for Latent Fingerprint Development on Unfired Cartridge Cases.

    Science.gov (United States)

    Xu, Jingyang; Zhang, Ziyuan; Zheng, Xiaochun; Bond, John W

    2017-05-01

    Visualization of latent fingerprints on metallic surfaces by the method of applying electrostatic charging and adsorption is considered as a promising chemical-free method, which has the merit of nondestruction, and is considered to be effective for some difficult situations such as aged fingerprint deposits or those exposed to environmental extremes. In fact, a portable electrostatic generator can be easily accessible in a local forensic technology laboratory, which is already widely used in the visualization of footwear impressions. In this study, a modified version of this electrostatic apparatus is proposed for latent fingerprint development and has shown great potential in visualizing fingerprints on metallic surfaces such as cartridge cases. Results indicate that this experimental arrangement can successfully develop aged latent fingerprints on metal surfaces, and we demonstrate its effectiveness compared with existing conventional fingerprint recovery methods. © 2016 American Academy of Forensic Sciences.

  10. Permanent disposal of radioactive particulate waste in cartridge containing ferromagnetic material

    International Nuclear Information System (INIS)

    Troy, M.

    1986-01-01

    This patent describes a cartridge for permanent disposal of solid radioactive particulate waste, comprising; a liquid impervious casing having an upper end cover, a lower end cover and a side wall extending between the covers, the casing enclosing a waste storage region; ferromagnetic fibrous material defining a waste retaining matrix and filling a major portion of the waste storage region; means defining an inlet conduit extending through the upper end cover and axially of the casing through the waste storage region, and opening into the waste storage region in the vicinity of the lower and end cover; and means defining first and second outlet conduits extending through the upper end cover and opening into the waste storage region in the vicinity of the upper end cover

  11. Rapid purification of radioiodinated peptides with Sep-Pak reversed phase cartridges and HPLC

    International Nuclear Information System (INIS)

    Miller, J.J.; Schultz, G.S.; Levy, R.S.

    1984-01-01

    A simple, rapid method is described for the purification of radioiodinated peptides for use in radioimmuno- and in radioreceptor assays. Iodinated reaction mixtures are applied directly onto Sep-Pak disposable, reversed phase cartridges equilibrated with phosphate buffer. Unreacted 125-iodide and other non-peptide reaction components are eluted with buffer. The peptide fraction is then eluted with 70% buffer:30% acetonitrile. The peptide fraction is further purified by reversed phase high pressure liquid chromatography to separate the native peptide and the mono- and diiodo-derivatives. In this study the method is used to prepare 125-iodide-labeled monoiodo-leucine enkephalin and monoiodo-angiotensin II, which are free of the parent peptides and diiodo-derivatives and are of maximum obtainable specific radioactivity. The usefulness of these labeled peptides in radioimmuno- and radioreceptor assays is demonstrated by their binding to specific antibodies and receptors, respectively. (author)

  12. Identifying persistent and characteristic features in firearm tool marks on cartridge cases

    Science.gov (United States)

    Ott, Daniel; Soons, Johannes; Thompson, Robert; Song, John

    2017-12-01

    Recent concerns about subjectivity in forensic firearm identification have motivated the development of algorithms to compare firearm tool marks that are imparted on ammunition and to generate quantitative measures of similarity. In this paper, we describe an algorithm that identifies impressed tool marks on a cartridge case that are both consistent between firings and contribute strongly to a surface similarity metric. The result is a representation of the tool mark topography that emphasizes both significant and persistent features across firings. This characteristic surface map is useful for understanding the variability and persistence of the tool marks created by a firearm and can provide improved discrimination between the comparison scores of samples fired from the same firearm and the scores of samples fired from different firearms. The algorithm also provides a convenient method for visualizing areas of similarity that may be useful in providing quantitative support for visual comparisons by trained examiners.

  13. A new screening method for amphetamine and methamphetamine using dansyl chloride derivatization and cartridge fluorescence.

    Science.gov (United States)

    Yamada, H; Ikeda-Wada, S; Oguri, K

    1998-07-01

    A new screening method for amphetamines was developed. It consists of derivatization with dansyl chloride, extraction of the derivative using a Sep-Pak C18 or a Bond Elut C18, solid phase extraction columns, and visualization of the fluorescence of the cartridge. A control test using drug-free urine showed no fluorescence. Amphetamine, methamphetamine and the methylenedioxy derivatives exhibited strong fluorescence, while related compounds, such as N-ethylamphetamine and fenetylline, were negative or weakly positive. The disadvantage of the present method is that it is a multi-step procedure and 20-30 min is required for screening. However, since it has a different specificity from the widely used immunochemical technique, it is suggested to be a useful screen for amphetamines.

  14. Special Analysis for the Disposal of the Idaho National Laboratory Unirradiated Light Water Breeder Reactor Rods and Pellets Waste Stream at the Area 5 Radioactive Waste Management Site, Nevada National Security Site, Nye County, Nevada

    Energy Technology Data Exchange (ETDEWEB)

    None

    2014-08-31

    The purpose of this special analysis (SA) is to determine if the Idaho National Laboratory (INL) Unirradiated Light Water Breeder Reactor (LWBR) Rods and Pellets waste stream (INEL103597TR2, Revision 2) is suitable for disposal by shallow land burial (SLB) at the Area 5 Radioactive Waste Management Site (RWMS). The INL Unirradiated LWBR Rods and Pellets waste stream consists of 24 containers with unirradiated fabricated rods and pellets composed of uranium oxide (UO2) and thorium oxide (ThO2) fuel in zirconium cladding. The INL Unirradiated LWBR Rods and Pellets waste stream requires an SA because the 229Th, 230Th, 232U, 233U, and 234U activity concentrations exceed the Nevada National Security Site (NNSS) Waste Acceptance Criteria (WAC) Action Levels.

  15. Determining the effect of cartridge case coatings on GSR using post-fire priming cup residue.

    Science.gov (United States)

    Terry, Molly; Fookes, Barry; Bridge, Candice M

    2017-07-01

    Ammunition is typically composed of a lead-based priming mixture which contributes to the characteristics most commonly used for the identification of gunshot residue (GSR). Due to the health risks often associated with lead, the use of lead-free primers in ammunitions is becoming more popular. Thus, the presence of GSR is becoming more difficult to discern based on the traditional means, i.e. the presence of lead (Pb), barium (Ba), and antimony (Sb). While research has been conducted on the differences between lead-based and lead-free muzzle discharge residue, few have researched other components of ammunition which may lead to other means of characterizing GSR. This research, therefore, covers that gap by focusing on the priming cup present in ammunition and the residue which may originate from it, that can contribute to muzzle discharge residue. In this study, a lead-based and a lead-free ammunition from four different manufacturers were chosen. The cartridges were fired using a Glock 17, 9mm Parabellum, collected post-fire, and subsequently de-primed resulting in the removal of the anvil. The GSR present on the anvils and cups was analyzed using scanning electron microscopy coupled with energy dispersive x-ray spectrometry (SEM-EDX). The data was then processed using unit vector analysis for normalization and analyzed using principal component analysis (PCA) and linear discriminant analysis (LDA). This data was then used to determine the components of the cartridge case which contribute to GSR and develop a method of characterization between lead-free and lead-based ammunition. Such a method will improve the detection of GSR by strengthening the criteria of identification. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Characterization of filter cartridges from the IEA-R1 reactor by radiochemical method

    International Nuclear Information System (INIS)

    Geraldo, Bianca; Vicente, Roberto; Ferreira, Robson J.; Goes, Marcos M.; Marumo, Julio T.

    2015-01-01

    The filter cartridges used in water purification system of research nuclear reactor IEA-R1 are considered radioactive wastes after their useful life. The characterization of these wastes is one of the stages of management, which aims to identify and quantify the radionuclides present, including those known as 'difficult to measure' (DTM) radionuclides. Establish a radiochemical analysis methodology for this type of waste is a difficult job, not only by the application of these techniques, but also by the amount of radionuclides that should be analyzed. In the waste produced in a nuclear reactor, the most important radionuclides are fission products, activation products and transuranic elements. Since these radionuclides emit gamma radiation not measurable in its decay process and consequently are difficult to measure, their concentrations can be estimated by indirect methods such as scale factors. This method is used to evaluate the DTM concentration, which is represented by alpha and beta nuclides using the correlation between them and the radionuclide key, a gamma emitter. The objective of this work is to describe a radiochemical analysis methodology for gamma emitter nuclides, present in the filter cartridges, evaluating the activity and concentrations by destructive assays. At the same time, two studies have been performed by non-destructive assays, the first one based on dose rates and the point kernel method to correlate the results and the second one based on calibration efficiency with Monte Carlo method. These studies belong to the radioactive waste characterization program that has been conducted at the Waste Management Laboratory of Nuclear and Energy Research Institute, IPEN-CNEN/SP. (author)

  17. Characterization of filter cartridges from the IEA-R1 reactor by radiochemical method

    Energy Technology Data Exchange (ETDEWEB)

    Geraldo, Bianca; Vicente, Roberto; Ferreira, Robson J.; Goes, Marcos M.; Marumo, Julio T., E-mail: bgeraldo@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2015-07-01

    The filter cartridges used in water purification system of research nuclear reactor IEA-R1 are considered radioactive wastes after their useful life. The characterization of these wastes is one of the stages of management, which aims to identify and quantify the radionuclides present, including those known as 'difficult to measure' (DTM) radionuclides. Establish a radiochemical analysis methodology for this type of waste is a difficult job, not only by the application of these techniques, but also by the amount of radionuclides that should be analyzed. In the waste produced in a nuclear reactor, the most important radionuclides are fission products, activation products and transuranic elements. Since these radionuclides emit gamma radiation not measurable in its decay process and consequently are difficult to measure, their concentrations can be estimated by indirect methods such as scale factors. This method is used to evaluate the DTM concentration, which is represented by alpha and beta nuclides using the correlation between them and the radionuclide key, a gamma emitter. The objective of this work is to describe a radiochemical analysis methodology for gamma emitter nuclides, present in the filter cartridges, evaluating the activity and concentrations by destructive assays. At the same time, two studies have been performed by non-destructive assays, the first one based on dose rates and the point kernel method to correlate the results and the second one based on calibration efficiency with Monte Carlo method. These studies belong to the radioactive waste characterization program that has been conducted at the Waste Management Laboratory of Nuclear and Energy Research Institute, IPEN-CNEN/SP. (author)

  18. Ways of increasing of efficiency of the use of chemical gazogene cartridges at the mining of facing raw material

    OpenAIRE

    Кальчук, Сергій Володимирович; Лукащук, Олександр Вікторович

    2016-01-01

    The analysis and theoretical generalizations of influencing of the known methods of separation to the stone on the array of breeds is executed. Certain backlogs of increase of the OIR use of chemical gazogene cartridges. Offered ways of determination of optimum parameters of most effective their applications on the deposits of facing stone.

  19. Oxidative dissolution of unirradiated Mimas MOX fuel (U/Pu oxides) in carbonated water under oxic and anoxic conditions

    Energy Technology Data Exchange (ETDEWEB)

    Odorowski, Mélina [CEA/DEN/DTCD/SECM/LMPA, BP 17171, 30207 Bagnols-sur-Cèze Cedex (France); MINES ParisTech, PSL Research University, Centre de Géosciences, 35 rue St Honoré, 77305 Fontainebleau (France); Jégou, Christophe, E-mail: christophe.jegou@cea.fr [CEA/DEN/DTCD/SECM/LMPA, BP 17171, 30207 Bagnols-sur-Cèze Cedex (France); De Windt, Laurent [MINES ParisTech, PSL Research University, Centre de Géosciences, 35 rue St Honoré, 77305 Fontainebleau (France); Broudic, Véronique; Peuget, Sylvain; Magnin, Magali; Tribet, Magaly [CEA/DEN/DTCD/SECM/LMPA, BP 17171, 30207 Bagnols-sur-Cèze Cedex (France); Martin, Christelle [Agence nationale pour la gestion des déchets radioactifs (Andra), DRD/CM, 1-7 rue Jean-Monnet, 92298 Châtenay-Malabry Cedex (France)

    2016-01-15

    Few studies exist concerning the alteration of Mimas Mixed-OXide (MOX) fuel, a mixed plutonium and uranium oxide, and data is needed to better understand its behavior under leaching, especially for radioactive waste disposal. In this study, two leaching experiments were conducted on unirradiated MOX fuel with a strong alpha activity (1.3 × 10{sup 9} Bq.g{sub MOX}{sup −1} reproducing the alpha activity of spent MOX fuel with a burnup of 47 GWd·t{sub HM}{sup −1} after 60 years of decay), one under air (oxic conditions) for 5 months and the other under argon (anoxic conditions with [O{sub 2}] < 1 ppm) for one year in carbonated water (10{sup −2} mol L{sup −1}). For each experiment, solution samples were taken over time and Eh and pH were monitored. The uranium in solution was assayed using a kinetic phosphorescence analyzer (KPA), plutonium and americium were analyzed by a radiochemical route, and H{sub 2}O{sub 2} generated by the water radiolysis was quantified by chemiluminescence. Surface characterizations were performed before and after leaching using Scanning Electron Microscopy (SEM), Electron Probe Microanalyzer (EPMA) and Raman spectroscopy. Solubility diagrams were calculated to support data discussion. The uranium releases from MOX pellets under both oxic and anoxic conditions were similar, demonstrating the predominant effect of alpha radiolysis on the oxidative dissolution of the pellets. The uranium released was found to be mostly in solution as carbonate species according to modeling, whereas the Am and Pu released were significantly sorbed or precipitated onto the TiO{sub 2} reactor. An intermediate fraction of Am (12%) was also present as colloids. SEM and EPMA results indicated a preferential dissolution of the UO{sub 2} matrix compared to the Pu-enriched agglomerates, and Raman spectroscopy showed the Pu-enriched agglomerates were slightly oxidized during leaching. Unlike Pu-enriched zones, the UO{sub 2} grains were much more

  20. Electrochemical corrosion studies on copper-base waste package container materials in unirradiated 0.1 N NaNO3 at 95 degrees C

    International Nuclear Information System (INIS)

    Akkaya, M.; Verink, E.D. Jr.; Van Konynenburg, R.A.

    1988-05-01

    Three candidate materials were investigated in this study in terms of their electrochemical corrosion behavior in unirradiated 0.1 N NaNO 3 solutions at 95 degrees C. Anodic polarization experiments were conducted to determine the passive current densities, pitting potentials, and other parameters, together with Cyclic Current Reversal Voltammetry tests to evaluate the stability and protectiveness of the passive oxides formed. X-ray diffraction and Auger Electron Spectroscopy were used for identification of the corrosion products as well as Scanning Electron Microscopy for the surface morphology studies. 2 refs., 22 figs., 2 tabs

  1. Oxide particle size distribution from shearing irradiated and unirradiated LWR fuels in Zircaloy and stainless steel cladding: significance for risk assessment

    International Nuclear Information System (INIS)

    Davis, W. Jr.; West, G.A.; Stacy, R.G.

    1979-01-01

    Sieve fractionation was performed with oxide particles dislodged during shearing of unirradiated or irradiated fuel bundles or single rods of UO 2 or 96 to 97% ThO 2 --3 to 4% UO 2 . Analyses of these data by nonlinear least-squares techniques demonstrated that the particle size distribution is lognormal. Variables involved in the numerical analyses include lognormal median size, lognormal standard deviation, and shear cut length. Sieve-fractionation data are presented for unirradiated bundles of stainless-steel-clad or Zircaloy-2-clad UO 2 or ThO 2 --UO 2 sheared into lengths from 0.5 to 2.0 in. Data are also presented for irradiated single rods (sheared into lengths of 0.25 to 2.0 in.) of Zircaloy-2-clad UO 2 from BWRs and of Zircaloy-4-clad UO 2 from PWRs. Median particle sizes of UO 2 from shearing irradiated stainless-steel-clad fuel ranged from 103 to 182 μm; particle sizes of ThO 2 --UO 2 , under these same conditions, ranged from 137 to 202 μm. Similarly, median particle sizes of UO 2 from shearing unirradiated Zircaloy-2-clad fuel ranged from 230 to 957 μm. Irradiation levels of fuels from reactors ranged from 9,000 to 28,000 MWd/MTU. In general, particle sizes from shearing these irradiated fuels are larger than those from the unirradiated fuels. In addition, variations in particle size parameters pertaining to samples of a single vendor varied as much as those between different vendors. The fraction of fuel dislodged from the cladding is nearly proportional to the reciprocal of the shear cut length, until the cut length attains some minimum value below which all fuel is dislodged. Particles of fuel are generally elongated with a long-to-short axis ratio usually less than 3. Using parameters of the lognormal distribution deduced from experimental data, realistic estimates can be made of fractions of dislodged fuel having dimensions less than specified values

  2. The indicating FTA elute cartridge a solid sample carrier to detect high-risk HPV and high-grade cervical lesions.

    Science.gov (United States)

    de Bie, Roosmarie P; Schmeink, Channa E; Bakkers, Judith M J E; Snijders, Peter J F; Quint, Wim G V; Massuger, Leon F A G; Bekkers, Ruud L M; Melchers, Willem J G

    2011-07-01

    The clinically validated high-risk human papillomavirus (hrHPV) Hybrid Capture 2 (HC2) and GP5+/6+-PCR assays were analyzed on an Indicating FTA Elute cartridge (FTA cartridge). The FTA cartridge is a solid dry carrier that allows safe transport of cervical samples. FTA cartridge samples were compared with liquid-based samples for hrHPV and high-grade cervical intraepithelial neoplasia (CIN) detection. One cervical sample was collected in a liquid-based medium, and one was applied to the FTA cartridge. DNA was eluted directly from the FTA cartridge by a simple elution step. HC2 and GP5+/6+-PCR assays were performed on both the liquid-based and the FTA-eluted DNA of 88 women. Overall agreement between FTA and liquid-based samples for the presence of hrHPV was 90.9% with GP5+/6+-PCR and 77.3% with HC2. The sensitivity for high-grade CIN of hrHPV testing on the FTA cartridges was 84.6% with GP5+/6+-PCR and only 53.8% with HC2. By comparison, these sensitivities on liquid-based samples were 92.3% and 100% for GP5+/6+-PCR and HC2, respectively. Therefore, the FTA cartridge shows reasonably good overall agreement for hrHPV detection with liquid-based media when using GP5+/6+-PCR but not HC2 testing. Even with GP5+/6+-PCR, the FTA cartridge is not yet capable of detecting all high-grade CIN lesions. Copyright © 2011 American Society for Investigative Pathology and the Association for Molecular Pathology. Published by Elsevier Inc. All rights reserved.

  3. Coagulation measurement from whole blood using vibrating optical fiber in a disposable cartridge.

    Science.gov (United States)

    Yaraş, Yusuf Samet; Gündüz, Ali Bars; Sağlam, Gökhan; Ölçer, Selim; Civitçi, Fehmi; Baris, İbrahim; Yaralioğlu, Göksenin; Urey, Hakan

    2017-11-01

    In clinics, blood coagulation time measurements are performed using mechanical measurements with blood plasma. Such measurements are challenging to do in a lab-on-a-chip (LoC) system using a small volume of whole blood. Existing LoC systems use indirect measurement principles employing optical or electrochemical methods. We developed an LoC system using mechanical measurements with a small volume of whole blood without requiring sample preparation. The measurement is performed in a microfluidic channel where two fibers are placed inline with a small gap in between. The first fiber operates near its mechanical resonance using remote magnetic actuation and immersed in the sample. The second fiber is a pick-up fiber acting as an optical sensor. The microfluidic channel is engineered innovatively such that the blood does not block the gap between the vibrating fiber and the pick-up fiber, resulting in high signal-to-noise ratio optical output. The control plasma test results matched well with the plasma manufacturer's datasheet. Activated-partial-thromboplastin-time tests were successfully performed also with human whole blood samples, and the method is proven to be effective. Simplicity of the cartridge design and cost of readily available materials enable a low-cost point-of-care device for blood coagulation measurements. (2017) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE).

  4. Unsuitability of using the DNPH-coated solid sorbent cartridge for determination of airborne unsaturated carbonyls

    Science.gov (United States)

    Ho, Steven Sai Hang; Ho, K. F.; Liu, W. D.; Lee, S. C.; Dai, W. T.; Cao, J. J.; Ip, H. S. S.

    2011-01-01

    Measurements of aldehydes and ketones are typically conducted by derivatization using sorbent cartridges coated with 2,4-dinitrophenylhydrazine (DNPH). The collected samples are eluted with acetonitrile and analyzed by high-pressure liquid chromatography coupled with an ultra-violet detector (HPLC/UV). This paper intends to examine artifacts about its suitability in identification of unsaturated carbonyls. Kinetic tests for acrolein, crotonaldehyde, methacrolein and methyl vinyl ketone (MVK) showed formations of carbonyl-DNP-hydrazone during sampling, which could further react with DNPH, resulting in undesired UV absorption products [e.g., carbonyl-DNP-hydrazone-DNPH (dimer) and 2(carbonyl-DNP-hydrazone)-DNPH (trimer)]. The dimerization and trimerization occurred for acrolein and MVK whereas only dimerization for crotonaldehyde and methacrolein. The polymerization products undoubtedly affect the integrity of the chromatogram, leading to misidentification and inaccurate quantification. Whether precautions taken during sampling and/or sample treatment could avoid or minimize this artifact has not been thoughtfully investigated. More often, such artifacts are usually overlooked by scientists when the data are reported.

  5. Microfluidic impact printer with interchangeable cartridges for versatile non-contact multiplexed micropatterning.

    Science.gov (United States)

    Ding, Yuzhe; Huang, Eric; Lam, Kit S; Pan, Tingrui

    2013-05-21

    Biopatterning has been increasingly used for well-defined cellular microenvironment, patterned surface topology, and guided biological cues; however, it meets challenges on biocompatibility, thermal and chemical sensitivity, as well as limited availability of reagents. In this paper, we aim at combining the desired features from non-contact inkjet printing and dot-matrix impact printing to establish a versatile multiplexed micropatterning platform, referred to as Microfluidic Impact Printer (MI-Printer), for emerging biomedical applications. Using this platform, we can achieve the distinct features of no cross-contamination, sub-microliter ink loading with a minimal dead volume, high-throughput printing, biocompatible non-contact processing, sequential patterning with self-alignment, wide adaptability for complex media (e.g., cell suspension or colloidal solutions), interchangeable/disposable cartridge design, and simple assembly and configuration, all highly desirable towards laboratory-based research and development. Specifically, the printing resolution of the MI-printer platform has been experimentally characterized and theoretically analysed. Optimal printing resolution of 80 μm has been repeatedly obtained. Furthermore, two useful functions of the MI-printer, multiplexed printing and combinatorial printing, have been experimentally demonstrated with less than 10 μm misalignment. Moreover, molecular and biological patterning, utilizing the multiplexed and combinatorial printing, has been implemented to illustrate the utility of this versatile printing technique for emerging biomedical applications.

  6. Double versus single cartridge of 4% articaine infiltration into the retro-molar area for lower third molar surgery.

    Science.gov (United States)

    Sawang, Kamonpun; Chaiyasamut, Teeranut; Kiattavornchareon, Sirichai; Pairuchvej, Verasak; Bhattarai, Bishwa Prakash; Wongsirichat, Natthamet

    2017-06-01

    There are no studies regarding 4% articaine infiltration injection into the retro-molar area for an impacted lower third molar (LITM) surgery. This study aimed to evaluate the efficacy of infiltration using 1.7 ml (single cartridge: SC) of 4% articaine versus 3.4 ml (double cartridges: DC) of 4% articaine with 1:100,000 epinephrine in LITM surgery. This study involved 30 healthy patients with symmetrical LITM. The patients were assigned to receive either a DC or SC of 4% articaine with 1:100,000 epinephrine as a local anesthetic for each operation. Onset, duration, profoundness, need for additional anesthetic administration, total volume of anesthetic used, vitality of the tooth, and pain score during operation were recorded. The DC of 4 % articaine had a significantly higher success rate (83.3%) than did the SC (53.3%; P molar region can be an alternative anesthetic for LITM surgery.

  7. The security management of spent filter cartridge in Qinshan phase 3 (heavy water reactor) nuclear power plant

    International Nuclear Information System (INIS)

    Xue Dahai

    2005-01-01

    Qinshan phase 3 nuclear power plant is the first CANDU plant that China fetched in from Canada, and both two units operate under well condition up to now. The radioactive wastes produced during the unit operation mainly include technical waste, spent resin, and spent filter cartridge. The spent filter cartridge is one important part both in the volume and radioactivity of the radioactive waste, and it is the important content of radioactive waste management. Different from PWR, part of high radioactive spent filter in CANDU unit comes from heavy water system such as moderator system. It has to be dried through blowing before replaced from the system. But this working procedure result the filtrate dreg become flexible, and it can bring on the risk of internal or external exposure. It is very important to pay high attention to control the contamination spread during spent filter inside transfer. (authors)

  8. Randomized Comparison of Two Vaginal Self-Sampling Methods for Human Papillomavirus Detection: Dry Swab versus FTA Cartridge

    OpenAIRE

    Catarino, Rosa; Vassilakos, Pierre; Bilancioni, Aline; Vanden Eynde, Mathieu; Meyer-Hamme, Ulrike; Menoud, Pierre-Alain; Guerry, Fr?d?ric; Petignat, Patrick

    2015-01-01

    Background Human papillomavirus (HPV) self-sampling (self-HPV) is valuable in cervical cancer screening. HPV testing is usually performed on physician-collected cervical smears stored in liquid-based medium. Dry filters and swabs are an alternative. We evaluated the adequacy of self-HPV using two dry storage and transport devices, the FTA cartridge and swab. Methods A total of 130 women performed two consecutive self-HPV samples. Randomization determined which of the two tests was performed f...

  9. Development and Preliminary Assessment of Hemoperfusion Cartridge with Tannic Acid for Toxic Proteins' Precipitation: An In Vitro Model

    Directory of Open Access Journals (Sweden)

    Valquíria Miwa Hanai Yoshida

    2016-09-01

    Full Text Available Charcoal hemoperfusion (CHP is one of the extracorporeal removal techniques that are used to remove toxins from the body. CHP generally is considered the preferred method for extracorporeal extraction of several toxins—toxins that are adsorbed by activated charcoal. Assessments of the tannic acid's protective effects on ophidian poisoning are associated with the toxic proteins' precipitation by tannic acid. The challenge in treating a snakebite lies in removing the injected poison with minimal damage to blood constituent proteins. An alternative is CHP, and this investigation proposed to develop a column for hemoperfuser cartridge, combining charcoal granules trapped between layers of polymeric material conjugated to tannic acid, using an in vitro model scaled to the Wistar rat, which can be tested in an animal model. The cartridge was evaluated using the 22 full factorial design, in duplicate, as a method to study the effects of granulated-charcoal size and tannic acid concentration on the hematologic profile (platelet and leukocyte counts and biochemical profile (total serum protein and albumin dosages of sheep blood. The results demonstrate that charcoal in hemoperfuser cartridge: (1 decreases the serum in sheep blood volume, as consequence, (2 increases the serum proteins' concentration, and (iii exerts slight influence on albumin. The inclusion of tannic acid in hemoperfuser column precipitates some of serum proteins and albumin, decreasing their concentrations in the plasma serum. In conclusion, based on these effects we can suggest the use of 0.02 g tannic acid concentration and 8–20 mesh granulated charcoal in hemoperfuser cartridge for precipitating toxic proteins from snake venoms.

  10. Influence Factors Regarding the Effectiveness of Automated Ballistic Comparison on 0.38 Special Caliber Bullets and Cartridge Cases.

    Science.gov (United States)

    Dos Santos, Lehi Sudy; Vieira Muterlle, Palloma

    2018-03-01

    Factors influencing effectiveness of automated comparisons, test-fired bullets, and cartridge cases from 0.38 Special revolvers were logged into the Evofinder ® Ballistic ID System. Tests were performed as follows: First test correlated test-fires of the same type, second test compared different types of ammunition components, third test replicated the second test in a larger database, and fourth test replicated the third test with students having no previous firearm identification experience. System effectiveness with projectiles in the first test was 0.89. With cartridge cases, effectiveness was 0.79 with combined results, but analysis of separate results by breech face and firing pin revealed low effectiveness by breech face (0.40). In the second, third, and fourth tests, effectiveness with projectiles were 0.61, 0.51, and 0.44. In addition, these tests had effectiveness with cartridge cases equivalent to 0.55, 0.43, and 0.44. Results are useful to establish routine protocols, system improvements, or comparative assessment of other electronic systems. © 2018 American Academy of Forensic Sciences.

  11. A patterned abrasion caused by the impact of a cartridge case may simulate an atypical muzzle imprint mark.

    Science.gov (United States)

    Kramer, Lena; Nadjem, Hadi; Glardon, Matthieu; Kneubuehl, Beat P; Pollak, Stefan; Große Perdekamp, Markus; Pircher, Rebecca

    2016-05-01

    In contact shots, the muzzle imprint is an informative finding associated with the entrance wound. It typically mirrors the constructional components being in line with the muzzle or just behind. Under special conditions, other patterned skin marks located near a gunshot entrance wound may give the impression to be part of the muzzle imprint. A potential mechanism causing a patterned pressure abrasion in close proximity to the bullet entrance site is demonstrated on the basis of a suicidal shot to the temple. The skin lesion in question appeared as a ring-shaped excoriation with a diameter corresponding to that of the cartridge case. Two hypotheses concerning the causative mechanism were investigated by test shots: - After being ejected, the cartridge case ricocheted inside a confined space (car cabin in the particular case) and secondarily hit the skin near the gunshot entrance wound. - The ejection of the cartridge case failed so that the case became stuck in the ejection port and its mouth contacted the skin when the body collapsed after being hit.

  12. Agreement for HPV genotyping detection between self-collected specimens on a FTA cartridge and clinician-collected specimens.

    Science.gov (United States)

    Guan, Yaoyao; Gravitt, Patti E; Howard, Roslyn; Eby, Yolanda J; Wang, Shaoming; Li, Belinda; Feng, Changyan; Qiao, You-Lin; Castle, Philip E

    2013-04-01

    The current method of transporting self-collected cervicovaginal specimen for HPV DNA testing relies on liquid based medium, which is challenging and expensive to transport. A novel, dry storage and transportation device, Whatman indicating FTA™ Elute Cartridge, avoids some of the pitfalls of liquid-based medium. This method has been shown to be comparable to liquid-based collection medium, but relative performance of self-collected (SC) and clinician-collected (CC) samples onto FTA cards has not been reported. The objective of this study is to compare the analytic performance of self- and clinician-collected samples onto FTA cartridges for the detection of carcinogenic HPV using Linear Array. There was a 91% agreement, 69% positive agreement, and kappa of 0.75 between the clinician-collected and self-collected specimens for detection of any carcinogenic HPV genotype. When the HPV results were categorized hierarchically according to cervical cancer risk, there was no difference in the distribution of the HPV results for the clinician- and self-collected specimens (p=0.7). This study concludes that FTA elute cartridge is a promising method of specimen transport for cervical cancer screening programs considering using self-collected specimen and HPV testing. Larger studies with clinical endpoints are now needed to assess the clinical performance. Copyright © 2012 Elsevier B.V. All rights reserved.

  13. Characterization of the water filters cartridges from the iea-r1 reactor using the Monte Carlo method

    International Nuclear Information System (INIS)

    Costa, Priscila; Potiens Junior, Ademar J.

    2015-01-01

    Filter cartridges are part of the primary water treatment system of the IEA-R1 Research Reactor and, when saturated, they are replaced and become radioactive waste. The IEA-R1 is located at the Nuclear and Energy Research Institute (IPEN), in Sao Paulo, Brazil. The primary characterization is the main step of the radioactive waste management in which the physical, chemical and radiological properties are determined. It is a very important step because the information obtained in this moment enables the choice of the appropriate management process and the definition of final disposal options. In this paper, it is presented a non-destructive method for primary characterization, using the Monte Carlo method associated with the gamma spectrometry. Gamma spectrometry allows the identification of radionuclides and their activity values. The detection efficiency is an important parameter, which is related to the photon energy, detector geometry and the matrix of the sample to be analyzed. Due to the difficult to obtain a standard source with the same geometry of the filter cartridge, another technique is necessary to calibrate the detector. The technique described in this paper uses the Monte Carlo method for primary characterization of the IEA-R1 filter cartridges. (author)

  14. Agreement for HPV genotyping detection between self-collected specimens on a FTA cartridge and clinician-collected specimens

    Science.gov (United States)

    Guan, YaoYao; Gravitt, Patti E.; Howard, Roslyn; Eby, Yolanda J.; Wang, Shaoming; Li, Belinda; Feng, Changyan; Qiao, You-Lin; Castle, Philip E.

    2016-01-01

    The current method of transporting self-collected cervicovaginal specimen for HPV DNA testing relies on liquid based medium, which is challenging and expensive to transport. A novel, dry storage and transportation device, Whatman indicating FTA™ Elute Cartridge, avoids some of the pitfalls of liquid-based medium. This method has been shown to be comparable to liquid-based collection medium, but relative performance of self-collected (SC) and clinician-collected (CC) samples onto FTA cards has not been reported. The objective of this study is to compare the analytic performance of self- and clinician-collected samples onto FTA cartridges for the detection of carcinogenic HPV using Linear Array. There was a 91% agreement, 69% positive agreement, and kappa of 0.75 between the clinician-collected and self-collected specimens for detection of any carcinogenic HPV genotype. When the HPV results were categorized hierarchically according to cervical cancer risk, there was no difference in the distribution of the HPV results for the clinician- and self-collected specimens (p = 0.7). This study concludes that FTA elute cartridge is a promising method of specimen transport for cervical cancer screening programs considering using self-collected specimen and HPV testing. Larger studies with clinical endpoints are now needed to assess the clinical performance. PMID:23370404

  15. Integration of an Optical Ring Resonator Biosensor into a Self-Contained Microfluidic Cartridge with Active, Single-Shot Micropumps

    Directory of Open Access Journals (Sweden)

    Sascha Geidel

    2016-09-01

    Full Text Available While there have been huge advances in the field of biosensors during the last decade, their integration into a microfluidic environment avoiding external tubing and pumping is still neglected. Herein, we show a new microfluidic design that integrates multiple reservoirs for reagent storage and single-use electrochemical pumps for time-controlled delivery of the liquids. The cartridge has been tested and validated with a silicon nitride-based photonic biosensor incorporating multiple optical ring resonators as sensing elements and an immunoassay as a potential target application. Based on experimental results obtained with a demonstration model, subcomponents were designed and existing protocols were adapted. The newly-designed microfluidic cartridges and photonic sensors were separately characterized on a technical basis and performed well. Afterwards, the sensor was functionalized for a protein detection. The microfluidic cartridge was loaded with the necessary assay reagents. The integrated pumps were programmed to drive the single process steps of an immunoassay. The prototype worked selectively, but only with a low sensitivity. Further work must be carried out to optimize biofunctionalization of the optical ring resonators and to have a more suitable flow velocity progression to enhance the system’s reproducibility.

  16. Domestic Preparedness: Phase 2 Sarin Vapor Challenge and Corn Oil Protection Factor (PF) Testing of Commercial Powered Air Purifying Respirator (PAPR) Systems and Cartridges

    National Research Council Canada - National Science Library

    Campbell, Lee E; Lins, Ray; Pappas, Alex G

    2002-01-01

    .... Results indicate that cartridges provide complete penetration resistance against 200 mg/m3 GB challenge concentrations for 60 minutes, but that unacceptably high levels of GB vapor and corn oil...

  17. Combining cationic and anionic mixed-mode sorbents in a single cartridge to extract basic and acidic pharmaceuticals simultaneously from environmental waters.

    Science.gov (United States)

    Salas, Daniela; Borrull, Francesc; Fontanals, Núria; Marcé, Rosa Maria

    2018-01-01

    The aim of the present study is to broaden the applications of mixed-mode ion-exchange solid-phase extraction sorbents to extract both basic and acidic compounds simultaneously by combining the sorbents in a single cartridge and developing a simplified extraction procedure. Four different cartridges containing negative and positive charges in the same configuration were evaluated and compared to extract a group of basic, neutral, and acidic pharmaceuticals selected as model compounds. After a thorough optimization of the extraction conditions, the four different cartridges showed to be capable of retaining basic and acidic pharmaceuticals simultaneously through ionic interactions, allowing the introduction of a washing step with 15 mL methanol to eliminate interferences retained by hydrophobic interactions. Using the best combined cartridge, a method was developed, validated, and further applied to environmental waters to demonstrate that the method is promising for the extraction of basic and acidic compounds from very complex samples.

  18. Detection and Genotyping of Human Papillomavirus in Self-Obtained Cervicovaginal Samples by Using the FTA Cartridge: New Possibilities for Cervical Cancer Screening ▿

    Science.gov (United States)

    Lenselink, Charlotte H.; de Bie, Roosmarie P.; van Hamont, Dennis; Bakkers, Judith M. J. E.; Quint, Wim G. V.; Massuger, Leon F. A. G.; Bekkers, Ruud L. M.; Melchers, Willem J. G.

    2009-01-01

    This study assesses human papillomavirus (HPV) detection and genotyping in self-sampled genital smears applied to an indicating FTA elute cartridge (FTA cartridge). The study group consisted of 96 women, divided into two sample sets. All samples were analyzed by the HPV SPF10-Line Blot 25. Set 1 consisted of 45 women attending the gynecologist; all obtained a self-sampled cervicovaginal smear, which was applied to an FTA cartridge. HPV results were compared to a cervical smear (liquid based) taken by a trained physician. Set 2 consisted of 51 women who obtained a self-sampled cervicovaginal smear at home, which was applied to an FTA cartridge and to a liquid-based medium. DNA was obtained from the FTA cartridges by simple elution as well as extraction. Of all self-obtained samples of set 1, 62.2% tested HPV positive. The overall agreement between self- and physician-obtained samples was 93.3%, in favor of the self-obtained samples. In sample set 2, 25.5% tested HPV positive. The overall agreement for high-risk HPV presence between the FTA cartridge and liquid-based medium and between DNA elution and extraction was 100%. This study shows that HPV detection and genotyping in self-obtained cervicovaginal samples applied to an FTA cartridge is highly reliable. It shows a high level of overall agreement with HPV detection and genotyping in physician-obtained cervical smears and liquid-based self-samples. DNA can be obtained by simple elution and is therefore easy, cheap, and fast. Furthermore, the FTA cartridge is a convenient medium for collection and safe transport at ambient temperatures. Therefore, this method may contribute to a new way of cervical cancer screening. PMID:19553570

  19. Detection and genotyping of human papillomavirus in self-obtained cervicovaginal samples by using the FTA cartridge: new possibilities for cervical cancer screening.

    Science.gov (United States)

    Lenselink, Charlotte H; de Bie, Roosmarie P; van Hamont, Dennis; Bakkers, Judith M J E; Quint, Wim G V; Massuger, Leon F A G; Bekkers, Ruud L M; Melchers, Willem J G

    2009-08-01

    This study assesses human papillomavirus (HPV) detection and genotyping in self-sampled genital smears applied to an indicating FTA elute cartridge (FTA cartridge). The study group consisted of 96 women, divided into two sample sets. All samples were analyzed by the HPV SPF(10)-Line Blot 25. Set 1 consisted of 45 women attending the gynecologist; all obtained a self-sampled cervicovaginal smear, which was applied to an FTA cartridge. HPV results were compared to a cervical smear (liquid based) taken by a trained physician. Set 2 consisted of 51 women who obtained a self-sampled cervicovaginal smear at home, which was applied to an FTA cartridge and to a liquid-based medium. DNA was obtained from the FTA cartridges by simple elution as well as extraction. Of all self-obtained samples of set 1, 62.2% tested HPV positive. The overall agreement between self- and physician-obtained samples was 93.3%, in favor of the self-obtained samples. In sample set 2, 25.5% tested HPV positive. The overall agreement for high-risk HPV presence between the FTA cartridge and liquid-based medium and between DNA elution and extraction was 100%. This study shows that HPV detection and genotyping in self-obtained cervicovaginal samples applied to an FTA cartridge is highly reliable. It shows a high level of overall agreement with HPV detection and genotyping in physician-obtained cervical smears and liquid-based self-samples. DNA can be obtained by simple elution and is therefore easy, cheap, and fast. Furthermore, the FTA cartridge is a convenient medium for collection and safe transport at ambient temperatures. Therefore, this method may contribute to a new way of cervical cancer screening.

  20. Rapid and sensitive determination of phenylurea herbicides in water in the presence of their anilines by extraction with a Carbopack cartridge followed by liquid chromatography.

    Science.gov (United States)

    Di Corcia, A; Marchetti, M

    1991-03-22

    A rapid and sensitive method for determining phenylurea herbicides in environmental aqueous samples in the presence of their anilines is described. The water sample is preconcentrated by passage at a flow-rate of ca. 150 ml/min through a 250-mg graphitized carbon black (Carbopack B) cartridge. After washing with 0.6 ml of methanol, the Carbopack B trap is connected with a cartridge containing a strong cation exchanger. Organics trapped by the Carbopack cartridge are eluted by passage of 6 ml of methylene chloride-methanol (95:5, v/v). Anilines and other basic compounds are quantitatively subtracted from the solvent system while flowing through the cation-exchange cartridge. After evaporation and redissolution, the sample is subjected to reversed-phase gradient elution high-performance liquid chromatography with UV detection at 250 nm. Recoveries of phenylureas added to water at levels between 30 and 3000 ng/l were higher than 92%. The limit of detection was about 1 ng/l, for a 2-1 sample. With respect to an octadecyl (C18)-bonded silica cartridge, the Carbopack B cartridge had a far better extraction efficiency for polar phenylureas.

  1. {sup 14}CO{sub 2} processing using an improved and robust molecular sieve cartridge

    Energy Technology Data Exchange (ETDEWEB)

    Wotte, Anja, E-mail: Anja.Wotte@uni-koeln.de [Institute of Geology and Mineralogy, University of Cologne, Cologne (Germany); Wordell-Dietrich, Patrick [Thünen Institute of Climate-Smart Agriculture, Braunschweig (Germany); Wacker, Lukas [Ion Beam Physics, ETH Zurich, Zurich (Switzerland); Don, Axel [Thünen Institute of Climate-Smart Agriculture, Braunschweig (Germany); Rethemeyer, Janet [Institute of Geology and Mineralogy, University of Cologne, Cologne (Germany)

    2017-06-01

    Radiocarbon ({sup 14}C) analysis on CO{sub 2} can provide valuable information on the carbon cycle as different carbon pools differ in their {sup 14}C signature. While fresh, biogenic carbon shows atmospheric {sup 14}C concentrations, fossil carbon is {sup 14}C free. As shown in previous studies, CO{sub 2} can be collected for {sup 14}C analysis using molecular sieve cartridges (MSC). These devices have previously been made of plastic and glass, which can easily be damaged during transport. We thus constructed a robust MSC suitable for field application under tough conditions or in remote areas, which is entirely made of stainless steel. The new MSC should also be tight over several months to allow long sampling campaigns and transport times, which was proven by a one year storage test. The reliability of the {sup 14}CO{sub 2} results obtained with the MSC was evaluated by detailed tests of different procedures to clean the molecular sieve (zeolite type 13X) and for the adsorption and desorption of CO{sub 2} from the zeolite using a vacuum rig. We show that the {sup 14}CO{sub 2} results are not affected by any contamination of modern or fossil origin, cross contamination from previous samples, and by carbon isotopic fractionation. In addition, we evaluated the direct CO{sub 2} transfer from the MSC into the automatic graphitization equipment AGE with the subsequent {sup 14}C AMS analysis as graphite. This semi-automatic approach can be fully automated in the future, which would allow a high sample throughput. We obtained very promising, low blank values between 0.0018 and 0.0028 F{sup 14}C (equivalent to 50,800 and 47,200 yrs BP), which are within the analytical background and lower than results obtained in previous studies.

  2. "1"4CO_2 processing using an improved and robust molecular sieve cartridge

    International Nuclear Information System (INIS)

    Wotte, Anja; Wordell-Dietrich, Patrick; Wacker, Lukas; Don, Axel; Rethemeyer, Janet

    2017-01-01

    Radiocarbon ("1"4C) analysis on CO_2 can provide valuable information on the carbon cycle as different carbon pools differ in their "1"4C signature. While fresh, biogenic carbon shows atmospheric "1"4C concentrations, fossil carbon is "1"4C free. As shown in previous studies, CO_2 can be collected for "1"4C analysis using molecular sieve cartridges (MSC). These devices have previously been made of plastic and glass, which can easily be damaged during transport. We thus constructed a robust MSC suitable for field application under tough conditions or in remote areas, which is entirely made of stainless steel. The new MSC should also be tight over several months to allow long sampling campaigns and transport times, which was proven by a one year storage test. The reliability of the "1"4CO_2 results obtained with the MSC was evaluated by detailed tests of different procedures to clean the molecular sieve (zeolite type 13X) and for the adsorption and desorption of CO_2 from the zeolite using a vacuum rig. We show that the "1"4CO_2 results are not affected by any contamination of modern or fossil origin, cross contamination from previous samples, and by carbon isotopic fractionation. In addition, we evaluated the direct CO_2 transfer from the MSC into the automatic graphitization equipment AGE with the subsequent "1"4C AMS analysis as graphite. This semi-automatic approach can be fully automated in the future, which would allow a high sample throughput. We obtained very promising, low blank values between 0.0018 and 0.0028 F"1"4C (equivalent to 50,800 and 47,200 yrs BP), which are within the analytical background and lower than results obtained in previous studies.

  3. Characterization of filters cartridges from the water polishing system of IEA-R1 reactor: radiometric methods

    International Nuclear Information System (INIS)

    Tessaro, Ana Paula G.; Vicente, Roberto

    2015-01-01

    The acceptance of radioactive waste in a repository depends primarily on knowledge of the radioisotopic inventory of the material, according to regulations established by regulatory agencies. The primary characterization is also a fundamental action to determine further steps in the management of the radioactive wastes. The aim of this work is to report the development of non-destructive methods for primary characterization of filters cartridges discarded as radioactive waste. The filters cartridges are used in the water polishing system of the IEA-R1 reactor retaining the particles in suspension in the reactor cooling water. The IEA-R1 is a pool type reactor with a thermal power of 5 MW, moderated and cooled with light water. It is located in the Energy and Nuclear Research Institute (IPEN-CNEN), in São Paulo, Brazil. The cartridge filters become radioactive waste when they are saturated and do not meet the required flow for the proper operation of the water polishing system. The activities of gamma emitters present in the filters are determined using gamma spectrometry, dose rate measurements and the Point Kernel Method to correlate results from both measurements. For the primary characterization, one alternative method is the radiochemical analysis of slices taken from each filter, what presents the disadvantage of higher exposures personnel and contamination risks. Another alternative method is the calibration of the measurement geometry of a gamma spectrometer, which requires the production of a standard filter. Both methods are necessary but can not be used in operational routine of radioactive waste management owing to cost and complexity. The method described can be used to determine routinely the radioactive inventory of these filters and other radioactive wastes, avoiding the necessity of destructive radiochemical analysis, or the necessity of calibrating the geometry of measurement. (author)

  4. A longitudinal evaluation of performance of automated BCR-ABL1 quantitation using cartridge-based detection system.

    Science.gov (United States)

    Enjeti, Anoop; Granter, Neil; Ashraf, Asma; Fletcher, Linda; Branford, Susan; Rowlings, Philip; Dooley, Susan

    2015-10-01

    An automated cartridge-based detection system (GeneXpert; Cepheid) is being widely adopted in low throughput laboratories for monitoring BCR-ABL1 transcript in chronic myelogenous leukaemia. This Australian study evaluated the longitudinal performance specific characteristics of the automated system.The automated cartridge-based system was compared prospectively with the manual qRT-PCR-based reference method at SA Pathology, Adelaide, over a period of 2.5 years. A conversion factor determination was followed by four re-validations. Peripheral blood samples (n = 129) with international scale (IS) values within detectable range were selected for assessment. The mean bias, proportion of results within specified fold difference (2-, 3- and 5-fold), the concordance rate of major molecular remission (MMR) and concordance across a range of IS values on paired samples were evaluated.The initial conversion factor for the automated system was determined as 0.43. Except for the second re-validation, where a negative bias of 1.9-fold was detected, all other biases fell within desirable limits. A cartridge-specific conversion factor and efficiency value was introduced and the conversion factor was confirmed to be stable in subsequent re-validation cycles. Concordance with the reference method/laboratory at >0.1-≤10 IS was 78.2% and at ≤0.001 was 80%, compared to 86.8% in the >0.01-≤0.1 IS range. The overall and MMR concordance were 85.7% and 94% respectively, for samples that fell within ± 5-fold of the reference laboratory value over the entire period of study.Conversion factor and performance specific characteristics for the automated system were longitudinally stable in the clinically relevant range, following introduction by the manufacturer of lot specific efficiency values.

  5. Sugar microanalysis by HPLC with benzoylation: improvement via introduction of a C-8 cartridge and a high efficiency ODS column.

    Science.gov (United States)

    Miyagi, Michiko; Yokoyama, Hirokazu; Hibi, Toshifumi

    2007-07-01

    An HPLC protocol for sugar microanalysis based on the formation of ultraviolet-absorbing benzoyl chloride derivatives was improved. Here, samples were prepared with a C-8 cartridge and analyzed with a high efficiency ODS column, in which porous spherical silica particles 3 microm in diameter were packed. These devices allowed us to simultaneously quantify multiple sugars and sugar alcohols up to 10 ng/ml and to provide satisfactory separations of some sugars, such as fructose and myo-inositol and sorbitol and mannitol. This protocol, which does not require special apparatuses, should become a powerful tool in sugar research.

  6. CSER 95-014: Criticality storage category for K Basin spent cartridge filters in ECOROK casks at central waste complex

    International Nuclear Information System (INIS)

    Miller, E.M.

    1996-01-01

    This CSER justifies storing K Basin spent cartridge filters in ECOROK 25-11 casks with liners under the limits in an existing criticality prevention specification, CPS-SW-149-00002, Rev./Mod. B-1, because the worst case fissionable material inventory is less then 1/2 the CPS limit and the cask is larger than allowed containers, the cask and liner have adequate iron content to meet the CPS requirements, and the cask concrete walls are thick enough to isolate the fissionable contents of each cask from neutron interaction with fissionable material external to each cask

  7. Inductively coupled plasma mass spectrometry study of the retention behavior of arsenic species on various solid phase extraction cartridges and its application in arsenic speciation

    Energy Technology Data Exchange (ETDEWEB)

    Yu Chunhai; Cai Qiantao E-mail: qtcai@cawt.sui.com.sg; Guo Zhongxian; Yang Zhaoguang; Khoo, Soo Beng

    2003-07-18

    Inductively coupled plasma mass spectrometry (ICP-MS) was used to investigate the retention behavior of arsenite, arsenate, monomethylarsonic acid (MMA), dimethylarsinic acid (DMA), arsenobetaine (AsB), arsenocholine (AsC), trimethylarsine oxide (TMAO) and tetramethylarsonium ion (TMAI) on various silica-based solid phase extraction (SPE) cartridges. A method for arsenic speciation is then developed on the basis of selective SPE separation of arsenic species and highly sensitive ICP-MS detection. Factors affecting the retention and elution of arsenic species were examined. Results showed that the retention of arsenic species depended on the chemical characteristics of arsenic species and the types of sorbent materials. Change of pH in the range of 2.0-9.0 did not show significant effects on the retention of DMA, AsB, AsC, TMAI and TMAO on an ethylbenzene sulfonic acid-based strong cation exchange (SCX-3) cartridge. pH also did not influence the retention of AsB, AsC, TMAI and TMAO on a mixed-mode (M-M) cartridge containing non-polar, strong cation exchange and strong anion exchange (SAX) functional groups. However, the retentions of As(V) and MMA on the SAX and the M-M cartridge changed with pH. As(V) and MMA were completely retained on the SAX cartridge and sequentially selectively eluted with 1.0 mol l{sup -1} acetic acid (for MMA). DMA, AsB, AsC, TMAI and TMAO were completely retained on the SCX-3 cartridge and sequentially selectively eluted with 1.0 mol l{sup -1} HNO{sub 3} (for DMA). As(V), MMA, AsB, AsC, TMAI and TMAO were completely retained on the M-M cartridge. As(III) was not retained on either cartridge and remained in solution. Arsenic species in solution and those eluted from the cartridges were subsequently determined by ICP-MS. A detection limit of 8 ng l{sup -1} arsenic in water sample was obtained. This method was successfully applied to arsenic speciation in various sources of water samples (drinking water, waste water, raw water, etc.) and US

  8. Positive detection of exfoliated colon cancer cells on linear stapler cartridges was associated with depth of tumor invasion and preoperative bowel preparation in colon cancer.

    Science.gov (United States)

    Ikehara, Kishiko; Endo, Shungo; Kumamoto, Kensuke; Hidaka, Eiji; Ishida, Fumio; Tanaka, Jun-Ichi; Kudo, Shin-Ei

    2016-08-31

    The aim of this study was to investigate exfoliated cancer cells (ECCs) on linear stapler cartridges used for anastomotic sites in colon cancer. We prospectively analyzed ECCs on linear stapler cartridges used for anastomosis in 100 colon cancer patients who underwent colectomy. Having completed the functional end-to-end anastomosis, the linear stapler cartridges were irrigated with saline, which was collected for cytological examination and cytological diagnoses were made by board-certified pathologists based on Papanicolaou staining. The detection rate of ECCs on the linear stapler cartridges was 20 %. Positive detection of ECCs was significantly associated with depth of tumor invasion (p = 0.012) and preoperative bowel preparation (p = 0.003). There were no marked differences between ECC-positive and ECC-negative groups in terms of the operation methods, tumor location, histopathological classification, and surgical margins. Since ECCs were identified on the cartridge of the linear stapler used for anastomosis, preoperative mechanical bowel preparation using polyethylene glycol solution and cleansing at anastomotic sites using tumoricidal agents before anastomosis may be necessary to decrease ECCs in advanced colon cancer.

  9. Dissolution rates of unirradiated UO2, UO2 doped with 233U, and spent fuel under normal atmospheric conditions and under reducing conditions using an isotope dilution method

    International Nuclear Information System (INIS)

    Ollila, Kaija; Albinsson, Yngve; Oversby, Virginia; Cowper, Mark

    2003-10-01

    The experimental results given in this report allow us to draw the following conclusions. 1) Tests using unirradiated fuel pellet materials from two different manufacturers gave very different dissolution rates under air atmosphere testing. Tests for fragments of pellets from different pellets made by the same manufacturer gave good agreement. This indicates that details of the manufacturing process have a large effect on the behavior of unirradiated UO 2 in dissolution experiments. Care must be taken in interpreting differences in results obtained in different laboratories because the results may be affected by manufacturing effects. 2) Long-term tests under air atmosphere have begun to show the effects of precipitation. Further testing will be needed before the samples reach steady state. 3) Testing of unirradiated UO 2 in systems containing an iron strip to produce reducing conditions gave [U] less than detection limits ( 235 U added as spike was recovered, indicating that 90% of the spike had precipitated onto the solid sample or the iron strip. 9) Tests of UO 2 pellet materials containing 233 U to provide an alpha decay activity similar to that expected for spent fuel 3000 and 10,000 years after disposal showed that the pellet materials behaved as expected under air atmosphere conditions, showing that the manufacturing method was successful. 10) Early testing of the 233 U-doped materials under reducing conditions showed relatively rapid (30 minute) dissolution of small amounts of U at the start of the puff test procedure. Results of analyses of an acidified fraction of the same solutions after 1 or 2 weeks holding indicate that the solutions were inhomogeneous, indicating the presence of colloidal material or small grains of solid. 11) Samples from the 233 U-doped tests initially indicated dissolution of solid during the first week of testing, with some indication of more rapid dissolution of the material with the higher doping. 12) The second cycle of testing

  10. Thermal enhancement cartridge heater modified tritium hydride bed development, Part 2 - Experimental validation of key conceptual design features

    Energy Technology Data Exchange (ETDEWEB)

    Heroux, K.J.; Morgan, G.A. [Savannah River Laboratory, Aiken, SC (United States)

    2015-03-15

    The Thermal Enhancement Cartridge Heater Modified (TECH Mod) tritium hydride bed is an interim replacement for the first generation (Gen1) process hydride beds currently in service in the Savannah River Site (SRS) Tritium Facilities. 3 new features are implemented in the TECH Mod hydride bed prototype: internal electric cartridge heaters, porous divider plates, and copper foam discs. These modifications will enhance bed performance and reduce costs by improving bed activation and installation processes, in-bed accountability measurements, end-of-life bed removal, and He-3 recovery. A full-scale hydride bed test station was constructed at the Savannah River National Laboratory (SRNL) in order to evaluate the performance of the prototype TECH Mod hydride bed. Controlled hydrogen (H{sub 2}) absorption/ desorption experiments were conducted to validate that the conceptual design changes have no adverse effects on the gas transfer kinetics or H{sub 2} storage/release properties compared to those of the Gen1 bed. Inert gas expansions before, during, and after H{sub 2} flow tests were used to monitor changes in gas transfer rates with repeated hydriding/de-hydriding of the hydride material. The gas flow rates significantly decreased after initial hydriding of the material; however, minimal changes were observed after repeated cycling. The data presented herein confirm that the TECH Mod hydride bed would be a suitable replacement for the Gen1 bed with the added enhancements expected from the advanced design features. (authors)

  11. Fast and Easy Drying Method for the Preparation of Activated [{sup 18}F]Fluoride Using Polymer Cartridge

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Jai Woong [Inha University, Inchon (Korea, Republic of); Lee, Byoung Se; Chi, Dae Yoon [FutureChem Co., Ltd., Seoul (Korea, Republic of); Lee, Sang Ju [Sogang University, Seoul (Korea, Republic of); Oh, Seung Jun [Asan Medical Center, University of Ulsan College of Medicine, Seoul (Korea, Republic of)

    2011-01-15

    An efficient nucleophilic [{sup 18}F]fluorination has been studied to reduce byproducts and preparation time. Instead of conventional aqueous solution of K{sub 2}CO{sub 3}-K{sub 222}, several organic solution containing inert organic salts were used to release [{sup 18}F]fluoride ion and anion bases captured in the polymer cartridge, concluding that methanol solution is the best choice. Comparing to azeotropic drying process, one min was sufficient to remove methanol completely, resulting in about 10% radioactivity saving by reducing drying time. The polymer cartridge, Chromafix (PS-HCO{sub 3}) was pretreated with several anion bases to displace pre-loaded bicarbonate base. Phosphate bases showed better results than carbonate bases in terms of lower basicity. tert-Butanol solvent used as a reaction media played another critical role in nucleophilic [{sup 18}F]fluorination by suppressing eliminated side product. Consequent [{sup 18}F]fluorination under the present condition afforded fast preparation of reaction solution and high radiochemical yields (98% radio-TLC, 84% RCY) with 94% of precursor remained.

  12. Development of a method for rapid and simultaneous monitoring of particulate and dissolved radiocesium in water with nonwoven fabric cartridge filters

    International Nuclear Information System (INIS)

    Hideki Tsuji; Tetsuo Yasutaka; Yoshihiko Kondo; Yasukazu Suzuki

    2014-01-01

    A method for the rapid and simultaneous monitoring of particulate and dissolved 137 Cs concentration in water was developed. This method uses pleated polypropylene nonwoven fabric filter to collect particulate radiocesium, and nonwoven fabric impregnated with Prussian blue (PB) to absorb dissolved radiocesium. The fabric was placed into cylindrical plastic cartridges (SS-cartridge and PB-cartridge). Traditional monitoring methods, such as evaporative concentration, often require time for pre-processing. However, this method described requires much less pre-processing time before the detection. Experiments conducted with simulated river water demonstrated that almost all of the suspended solids weight was collected in the SS-cartridge, and that more than 92 % of dissolved 137 Cs was absorbed onto the two PB-cartridges by 2.5 L/min flow rate when the range of the pH was 6-8. This device was applied to monitor Abukuma River water at two locations and the results were compared with those obtained using the filtrating and evaporative concentration method. The suspended solids concentration in river water, calculated by weight gain of the SS-cartridge and by sediment weight after filtration with a 0.45-μm membrane filter, agreed well. The radioactivity of the particulate and dissolved 137 Cs also agreed well in one of the two replications of this method. In addition, the required time for pre-processing was reduced by 60 times that by filtrating and evaporative concentration method. This method can separately collect and concentrate particulate and dissolved radiocesium rapidly and simultaneously in the field. (author)

  13. Separation of V(V)-4-(2-pyridylazo)resorcinolato complex from a large excess reagent using an ODS cartridge for high-performance liquid chromatography.

    Science.gov (United States)

    Takahashi, Toru; Kaneko, Emiko; Yotsuyanagi, Takao

    2006-12-01

    A selective off-line preconcentration technique for the V(V) complex with 4-(2-pyridylazo)resorcinol has been developed and successfully applied to the determination of V(V) in an air-borne sample. The target complex was separated from excess reagent using an ODS cartridge and water as the eluent. The complex was then concentrated on another ODS cartridge using tetrabutylammonium bromide and eluted with methanol; the eluate was applied to a one-drop concentration/HPLC. A detection limit as low as (6.05 +/- 0.82)x 10(-11) M (5 ppt) was achieved.

  14. The active personnel dosimeter---APFEL enterprises superheated drop detector

    International Nuclear Information System (INIS)

    Ipe, N.E.; Donahue, R.J.; Busick, D.D.

    1991-03-01

    The Active Personnel Dosimeter (APD) provides a digital readout of events caused by neutrons interacting with superheated liquid droplets. The droplets are suspended in a gel held in a replaceable cartridge. Upon neutron interaction, the superheated droplet vaporizes, forming a bubble. The sound produced in this process is recorded by transducers that sense the accompanying pressure pulse. The APD electronically discriminates against spurious noise and vibration. Studies with the production prototype APDs indicate that the detector response is linear up to about 0.40 mSv, with large variations sometimes from predicted values and between cartridges at higher dose equivalents. The response to standard neutron sources (bare 252 Cf, PuBe, PuB, PuF, PuLi) is reported and compared with the expected response. Unirradiated cartridges self-nucleate when heated to temperatures of 46 degrees C. The APD is insensitive to low-energy photons but responds to high-energy photons and electrons. 8 refs., 2 figs., 3 tabs

  15. Construction of a mutagenesis cartridge for poliovirus genome-linked viral protein: isolation and characterization of viable and nonviable mutants

    International Nuclear Information System (INIS)

    Kuhn, R.J.; Tada, H.; Ypma-Wong, M.F.; Dunn, J.J.; Semler, B.L.; Wimmer, E.

    1988-01-01

    By following a strategy of genetic analysis of poliovirus, the authors have constructed a synthetic mutagenesis cartridge spanning the genome-linked viral protein coding region and flanking cleavage sites in an infectious cDNA clone of the type I (Mahoney) genome. The insertion of new restriction sites within the infectious clone has allowed them to replace the wild-type sequences with short complementary pairs of synthetic oligonucleotides containing various mutations. A set of mutations have been made that create methionine codons within the genome-linked viral protein region. The resulting viruses have growth characteristics similar to wild type. Experiments that led to an alteration of the tyrosine residue responsible for the linkage to RNA have resulted in nonviable virus. In one mutant, proteolytic processing assayed in vitro appeared unimpaired by the mutation. They suggest that the position of the tyrosine residue is important for genome-linked viral protein function(s)

  16. The Effect of E-Selen Antioxidant on the Fatty Acids Content of the Homogenate of Unirradiated and Irradiated Pupae of Ceratitis Capitata

    International Nuclear Information System (INIS)

    Zaghloul, Y.S.; Abbassy, S.A.; Elakhdar, E.A.H.; Elakhdar, E.A.H.

    2011-01-01

    As antioxidant E-selen was added to the larval artificial diets of the Mediterranean fruit fly, Ceratitis capitata. The produced full grown pupae were exposed to gamma rays at dose rate of 90 Gy. The fatty acid contents of the normal and irradiated insects were analyzed to test to what extent, the uptake of the antioxidant will ameliorate the physiological damage induced to the medfly pupae, as a result of their exposure to irradiation. The results obtained by using Gas-liquid chromatography of fatty acid methyl esters, showed the palmitic and oleic acids to be the most predominant fatty acids in all pupal homogenates in both normal and irradiated pupae, either by the uptake of doses of the E-selen or without. The uptake of E-Selen with a dose of 0.3 mg led to a complete absence of the lauric and myristic acids in the homogenates of the unirradiated pupae of the medfly. This absence of lauric and myristic acids was accompanied by a decrease in the concentrations of the palmitic and linoleic acids reaching 25.17% and 32.98%, respectively as compared to pupae without the uptake of antioxidant. The concentrations of both the stearic and oleic acids showed an obvious increment reaching 199.22% and 58.94%, respectively, relative to those reared on the defined media and no added E.Selen. Exposure of the pupae to a dose of 90 Gy, resulted in an increment in the concentrations of the saturated lauric and myristic acid reaching 96.77% and 34.07%, respectively, relative to the untreated ones. While, at the same dose level, there were decrements in the concentrations of the palmitic, stearic, oleic and linoleic acids with percentages reaching 6.4, 9.22, 3.65 and 1.15%, respectively as compared to unirradiated controls. Irradiation of the pupae with sterilizing dose (90 Gy) after up taking the E-Selen in their larval diets, led to the increase of the concentrations of lauric, oleic and linoleic acids by ratios of 16.82, 8.84 and 29.26%, respectively as compared to their

  17. Thermal conductivity of fully dense unirradiated UO2: A new formulation from experimental results between 100 deg. C and 2500 deg. C, and associated fundamental properties

    International Nuclear Information System (INIS)

    Delette, G.; Charles, M.

    1997-01-01

    The various contributions to the thermal conductivity of UO 2 are first reviewed: contribution from phonons is preponderant up to 1600 deg. C; radiative contribution is negligible in the case of a polycrystalline sample, and is unable to account for the increase in conductivity observed above 1600 deg. C; electronic contribution, which seems patently to be responsible for this increase, is efficient from 1400 deg. C (electron-hole pairs treated as small polarons). Given the lack of decisive arguments on their actual efficiency, it was decided that, for temperatures above 2400 deg. C, neither a possible decrease in the electronic contribution due to vacancies, nor an additional possible contribution from Frenkel pairs would be described. We do not go therefore beyond the above-mentioned electronic contribution. In the light of these considerations, the law established by CEA for the thermal conductivity of unirradiated UO 2 , on the basis of a homogeneous set of measurements between 100 deg. C and 2500 deg. C, has been revised. A least-square method applied to the above measurements was used to derive simultaneously the four adjustable constants of the law which is henceforth proposed: λ = 1/A + BT+C/T 2 exp(-W/kT). The values of A, B, C, and W obtained, have the advantage of giving a better account of the high temperature results compared to the Martin recommendations (which has, by the way, the same physical form as above). Furthermore, this new law allows an extrapolation towards the melting point which is better founded than the earlier CEA law, while still respecting the value of the integrated thermal conductivity up to melting. Finally, various burnup effects (impurities, stoichiometry, etc.) can be formulated in physical terms. Moreover, the values of various fundamental properties connected with the derived constants have been determined: Debye temperature, Grueneisen parameter, Mott-Hubbard energy, electrical conductivity. These values are discussed and

  18. [Effectiveness of FTA Elute® indicating cartridge in combination with hybrid capture 2 for cervical cancer screening].

    Science.gov (United States)

    Chen, Feng; Zhang, Xi; Wang, Shaoming; Hu, Shangying; Chen, Wen; Zhao, Fanghui; He, Wei; Zhang, Yuqing; Qiao, Youlin

    2015-02-01

    To evaluate the effectiveness of FTA Elute® Cartridge (GE healthcare, Kent, UK) in combination with hybrid capture 2 (HC2) testing for cervical cancer screening. From May to June 2012, 412 women aged 25 to 65 years in Jiangxi Tonggu were enrolled in the study. We used pathological outcome as the gold standard, and the accuracy of the FTA card in combination with HC2 testing was investigated from both physician- and self-sampling, respectively. Physician sampling using the FTA card in combination with HC2 testing showed a comparable sensitivity (12/13) with the liquid based medium, but a higher specificity 69.5% (266/383) vs (77.8%, 298/383) (P FTA card in combination with HC2 testing with liquid based medium was 10/13 vs 8/13(P = 0.625) and (62.3%, 238/382) vs (75.7%, 289/382) (P FTA and liquid-based sampling medium was 86.1% (340/395) and 79.5% (314/395). For physician-collected samples used for HC2 testing to detect CIN2+, the accuracy of the FTA card was superior to that of the liquid-based medium (area under the receiver operating characteristic curve (AUC) = 0.898, 95%CI:0.838-0.958). FTA Elute® cartridge in combination with HC2 testing is a promising method of specimen transport for cervical cancer screening programs with a good precision.With further optimization, it could become an effective method for cervical cancer screening in various economic levels of areas.

  19. Preparation of a New Adsorbent from Activated Carbon and Carbon Nanofiber (AC/CNF for Manufacturing Organic-Vacbpour Respirator Cartridge

    Directory of Open Access Journals (Sweden)

    Mehdi Jahangiri

    2013-01-01

    Full Text Available In this study a composite of activated carbon and carbon nanofiber (AC/CNF was prepared to improve the performance of activated carbon (AC for adsorption of volatile organic compounds (VOCs and its utilization for respirator cartridges. Activated carbon was impregnated with a nickel nitrate catalyst precursor and carbonnanofibers (CNF were deposited directly on the AC surface using catalytic chemical vapor deposition. Deposited CNFs on catalyst particles in AC micropores, were activated by CO2 to recover the surface area and micropores.Surface and textural characterizations of the prepared composites were investigated using Brunauer, Emmett andTeller’s (BET technique and electron microscopy respectively. Prepared composite adsorbent was tested forbenzene, toluene and xylene (BTX adsorption and then employed in an organic respirator cartridge in granularform. Adsorption studies were conducted by passing air samples through the adsorbents in a glass column at an adjustable flow rate. Finally, any adsorbed species not retained by the adsorbents in the column were trapped in a charcoal sorbent tube and analyzed by gas chromatography. CNFs with a very thin diameter of about 10-20 nmwere formed uniformly on the AC/CNF. The breakthrough time for cartridges prepared with CO2 activated AC/CNF was 117 minutes which are significantly longer than for those cartridges prepared with walnut shell- based activated carbon with the same weight of adsorbents. This study showed that a granular form CO2 activated AC/CNF composite could be a very effective alternate adsorbent for respirator cartridges due to its larger adsorption capacities and lower weight.

  20. Time since discharge of 9mm cartridges by headspace analysis, part 1: Comprehensive optimisation and validation of a headspace sorptive extraction (HSSE) method.

    Science.gov (United States)

    Gallidabino, M; Romolo, F S; Weyermann, C

    2017-03-01

    Estimating the time since discharge of spent cartridges can be a valuable tool in the forensic investigation of firearm-related crimes. To reach this aim, it was previously proposed that the decrease of volatile organic compounds released during discharge is monitored over time using non-destructive headspace extraction techniques. While promising results were obtained for large-calibre cartridges (e.g., shotgun shells), handgun calibres yielded unsatisfying results. In addition to the natural complexity of the specimen itself, these can also be attributed to some selective choices in the methods development. Thus, the present series of paper aimed to more systematically evaluate the potential of headspace analysis to estimate the time since discharge of cartridges through the use of more comprehensive analytical and interpretative techniques. Specifically, in this first part, a method based on headspace sorptive extraction (HSSE) was comprehensively optimised and validated, as the latter recently proved to be a more efficient alternative than previous approaches. For this purpose, 29 volatile organic compounds were preliminary selected on the basis of previous works. A multivariate statistical approach based on design of experiments (DOE) was used to optimise variables potentially involved in interaction effects. Introduction of deuterated analogues in sampling vials was also investigated as strategy to account for analytical variations. Analysis was carried out by selected ion mode, gas chromatography coupled to mass spectrometry (GC-MS). Results showed good chromatographic resolution as well as detection limits and peak area repeatability. Application to 9mm spent cartridges confirmed that the use of co-extracted internal standards allowed for improved reproducibility of the measured signals. The validated method will be applied in the second part of this work to estimate the time since discharge of 9mm spent cartridges using multivariate models. Copyright

  1. Thermal conductivity of fully dense unirradiated UO{sub 2}: A new formulation from experimental results between 100 deg. C and 2500 deg. C, and associated fundamental properties

    Energy Technology Data Exchange (ETDEWEB)

    Delette, G; Charles, M [Commissariat a l` Energie Atomique, Grenoble (France)

    1997-08-01

    The various contributions to the thermal conductivity of UO{sub 2} are first reviewed: contribution from phonons is preponderant up to 1600 deg. C; radiative contribution is negligible in the case of a polycrystalline sample, and is unable to account for the increase in conductivity observed above 1600 deg. C; electronic contribution, which seems patently to be responsible for this increase, is efficient from 1400 deg. C (electron-hole pairs treated as small polarons). Given the lack of decisive arguments on their actual efficiency, it was decided that, for temperatures above 2400 deg. C, neither a possible decrease in the electronic contribution due to vacancies, nor an additional possible contribution from Frenkel pairs would be described. We do not go therefore beyond the above-mentioned electronic contribution. In the light of these considerations, the law established by CEA for the thermal conductivity of unirradiated UO{sub 2}, on the basis of a homogeneous set of measurements between 100 deg. C and 2500 deg. C, has been revised. A least-square method applied to the above measurements was used to derive simultaneously the four adjustable constants of the law which is henceforth proposed: {lambda} = 1/A + BT+C/T{sup 2}exp(-W/kT). The values of A, B, C, and W obtained, have the advantage of giving a better account of the high temperature results compared to the Martin recommendations (which has, by the way, the same physical form as above). Furthermore, this new law allows an extrapolation towards the melting point which is better founded than the earlier CEA law, while still respecting the value of the integrated thermal conductivity up to melting. Finally, various burnup effects (impurities, stoichiometry, etc.) can be formulated in physical terms. Moreover, the values of various fundamental properties connected with the derived constants have been determined: Debye temperature, Grueneisen parameter, Mott-Hubbard energy, electrical conductivity. These values

  2. Randomized Comparison of Two Vaginal Self-Sampling Methods for Human Papillomavirus Detection: Dry Swab versus FTA Cartridge.

    Science.gov (United States)

    Catarino, Rosa; Vassilakos, Pierre; Bilancioni, Aline; Vanden Eynde, Mathieu; Meyer-Hamme, Ulrike; Menoud, Pierre-Alain; Guerry, Frédéric; Petignat, Patrick

    2015-01-01

    Human papillomavirus (HPV) self-sampling (self-HPV) is valuable in cervical cancer screening. HPV testing is usually performed on physician-collected cervical smears stored in liquid-based medium. Dry filters and swabs are an alternative. We evaluated the adequacy of self-HPV using two dry storage and transport devices, the FTA cartridge and swab. A total of 130 women performed two consecutive self-HPV samples. Randomization determined which of the two tests was performed first: self-HPV using dry swabs (s-DRY) or vaginal specimen collection using a cytobrush applied to an FTA cartridge (s-FTA). After self-HPV, a physician collected a cervical sample using liquid-based medium (Dr-WET). HPV types were identified by real-time PCR. Agreement between collection methods was measured using the kappa statistic. HPV prevalence for high-risk types was 62.3% (95%CI: 53.7-70.2) detected by s-DRY, 56.2% (95%CI: 47.6-64.4) by Dr-WET, and 54.6% (95%CI: 46.1-62.9) by s-FTA. There was overall agreement of 70.8% between s-FTA and s-DRY samples (kappa = 0.34), and of 82.3% between self-HPV and Dr-WET samples (kappa = 0.56). Detection sensitivities for low-grade squamous intraepithelial lesion or worse (LSIL+) were: 64.0% (95%CI: 44.5-79.8) for s-FTA, 84.6% (95%CI: 66.5-93.9) for s-DRY, and 76.9% (95%CI: 58.0-89.0) for Dr-WET. The preferred self-collection method among patients was s-DRY (40.8% vs. 15.4%). Regarding costs, FTA card was five times more expensive than the swab (~5 US dollars (USD)/per card vs. ~1 USD/per swab). Self-HPV using dry swabs is sensitive for detecting LSIL+ and less expensive than s-FTA. International Standard Randomized Controlled Trial Number (ISRCTN): 43310942.

  3. Randomized Comparison of Two Vaginal Self-Sampling Methods for Human Papillomavirus Detection: Dry Swab versus FTA Cartridge.

    Directory of Open Access Journals (Sweden)

    Rosa Catarino

    Full Text Available Human papillomavirus (HPV self-sampling (self-HPV is valuable in cervical cancer screening. HPV testing is usually performed on physician-collected cervical smears stored in liquid-based medium. Dry filters and swabs are an alternative. We evaluated the adequacy of self-HPV using two dry storage and transport devices, the FTA cartridge and swab.A total of 130 women performed two consecutive self-HPV samples. Randomization determined which of the two tests was performed first: self-HPV using dry swabs (s-DRY or vaginal specimen collection using a cytobrush applied to an FTA cartridge (s-FTA. After self-HPV, a physician collected a cervical sample using liquid-based medium (Dr-WET. HPV types were identified by real-time PCR. Agreement between collection methods was measured using the kappa statistic.HPV prevalence for high-risk types was 62.3% (95%CI: 53.7-70.2 detected by s-DRY, 56.2% (95%CI: 47.6-64.4 by Dr-WET, and 54.6% (95%CI: 46.1-62.9 by s-FTA. There was overall agreement of 70.8% between s-FTA and s-DRY samples (kappa = 0.34, and of 82.3% between self-HPV and Dr-WET samples (kappa = 0.56. Detection sensitivities for low-grade squamous intraepithelial lesion or worse (LSIL+ were: 64.0% (95%CI: 44.5-79.8 for s-FTA, 84.6% (95%CI: 66.5-93.9 for s-DRY, and 76.9% (95%CI: 58.0-89.0 for Dr-WET. The preferred self-collection method among patients was s-DRY (40.8% vs. 15.4%. Regarding costs, FTA card was five times more expensive than the swab (~5 US dollars (USD/per card vs. ~1 USD/per swab.Self-HPV using dry swabs is sensitive for detecting LSIL+ and less expensive than s-FTA.International Standard Randomized Controlled Trial Number (ISRCTN: 43310942.

  4. Improvements of the sensitivity of burst cartridge detection; Amelioration du seuil de detection des ruptures de gaine

    Energy Technology Data Exchange (ETDEWEB)

    Vasnier, F [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1967-07-01

    I - Special tests for improving the sensitivity of burst cartridge detection equipment in power reactors II - Scintillator purge-flow tests using aged gas in the B.C.D. /E.D.F. 2 Summary. - The first part of this report describes the tests carried out on fission product detectors by a process in which gas is continuously injected in front of the scintillator. Using this system, the background is reduced and perturbations caused by pneumatic switches on the prospecting circuits are eliminated. The quality of the signals thus obtained permits better processing of the data and thus leads to a possible improvement in the sensitivity of burst cartridge detection. The second part gives results of tests carried out with both fresh and aged gases, the economic advantage of the latter being that it permits recycling through the reactor. Reduction of the background is less pronounced but the advantage of the stable signals is conserved. (author) [French] I - Essais speciaux pour ameliorer le seuil de detection des installations de D.R.G. des reacteurs de puissance II- Essais de balayage sous scintillateur avec gaz vieilli a la D.R.G. /E.D.F. 2 Sommaire. - La premiere partie de ce rapport decrit les essais effectues sur les detecteurs de produits de fission par un procede d'injection continue de gaz sous le scintillateur. Grace a ce systeme on obtient une reduction du bruit de fond et l'elimination des perturbations causees par les commutations pneumatiques des circuits de prospection. La qualite des signaux obtenus ainsi permet un meilleur traitement des informations d'ou une amelioration possible du seuil de detection des ruptures de gaines. La seconde partie donne les resultats d'essais effectues avec du gaz propre et vieilli, l'utilisation de ce dernier presentant l'avantage economique d'etre recycle du reacteur. La reduction du bruit de fond est moins importante mais on conserve l'avantage de la stabilisation des signaux. (auteur)

  5. Lyophilization Cycle Design for Dual Chamber Cartridges and a Method for Online Process Control: The "DCC LyoMate" Procedure.

    Science.gov (United States)

    Korpus, Christoph; Friess, Wolfgang

    2017-08-01

    Freeze-drying process design is a challenging task that necessitates a profound understanding of the complex interrelation among critical process parameters (e.g., shelf temperature and chamber pressure), heat transfer characteristics of the involved materials (e.g., product containers and holder devices), and critical quality attributes of the product (e.g., collapse temperatures). The Dual Chamber Cartridge "(DCC) LyoMate" (from lyophilization and automated) is a manometric temperature measurement-based process control strategy that was developed within this study to streamline this complicated task. It was successfully applied using 5% sucrose formulations with 0.5 and 1 mL fill volumes. The system was further challenged using 2, 20, and 100 mg/mL monoclonal antibody formulations. The DCC LyoMate method did not only produce pharmaceutically acceptable cakes but was also able to maintain the desired product temperature irrespective of formulation and protein content. It enabled successful process design even at high protein concentrations and aided the design and online control of the lyophilization process for drying in DCCs within a single development run. Thus, it helps to reduce development cost and the DCC LyoMate can also be easily installed on every freeze-dryer capable of performing a manometric temperature measurement, without the need for hardware modification. Copyright © 2017 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

  6. Comparison between a commercial solid-phase extraction cartridge and a home-made silver containing charcoal column: purification of Mo-99 from I-131 and Te-121

    International Nuclear Information System (INIS)

    Dias, Carla Roberta; Teodoro, Rodrigo; Osso Junior, Joao

    2011-01-01

    Among the radioisotopes used for medical application in Nuclear Medicine, 99m Tc, readily available from the elution of 99 Mo/ 99m Tc generators, is the most used, responsible for more than eighty percent of the total applications. These generators use the 99 Mo radioisotope that is produced in nuclear reactors and IPEN imports all the 99 Mo used in Brazil, mainly from Canada (Nordion). Due to the increasing needs of the Nuclear Medicine in Brazil and the world shortage of 99 Mo observed since 2008, IPEN decided to construct a new research reactor named Brazilian Multipurpose Reactor (BMR) as well as to develop the production of 99 Mo through the route of 235 U fission using a CINTICHEM modified separation process. The 99 Mo obtained from this process contains some contaminants and need to be purified. The aim of this work is to compare the preliminary results of the purification step of the solution containing 99 Mo and the contaminants, 131 I and 121 Te in the silver containing charcoal column and a solid-phase extraction cartridge. The purification process of 99 Mo coming from fission LEU foils was performed by adsorption chromatography using a home-made activated charcoal containing silver column (AC-Ag) and a commercial solid-phase extraction cartridge (OnGuard II Ag). High yields of 99 Mo elution and high retention of 131 I were achieved in the AC-Ag column and silver cartridge but 121 Te was more retained in the cartridge than in the AC-Ag column. (author)

  7. Comparison of a gel column blood typing method and a point-of-care cartridge for dog erythrocyte antigen 1.1.

    Science.gov (United States)

    Blois, Shauna L; Richardson, Danielle M; Abrams-Ogg, Anthony C G

    2013-01-01

    Blood typing for the presence of Dog Erythrocyte Antigen (DEA) 1.1 is recommended in all donor and recipient dogs prior to transfusion of blood products. The objective of this study was to determine if a point-of-care DEA 1.1 blood typing cartridge could be used in place of the gel column typing method. Detection of DEA 1.1 was performed using a laboratory-based gel column method and a point-of-care cartridge. A convenience sample of 30 healthy blood donors, 13 dogs with immune-mediated hemolytic anemia (IMHA) (3 of which had concurrent immune-mediated thrombocytopenia [IMT]), and 44 dogs with other diseases was included in the study. Agreement was observed between the tests for normal dogs and dogs with nonimmune-mediated disease in 74/74 cases. Two dogs in the IMHA group had indeterminate gel column blood typing results; 1 dog in this group had a negative gel column test result but a positive cartridge test result. There was good agreement between the 2 methods for normal dogs and dogs with nonimmune-mediated disease. Blood typing methods in dogs with IMHA should be further investigated. © Veterinary Emergency and Critical Care Society 2013.

  8. Proteoglycan from salmon nasal cartridge promotes in vitro wound healing of fibroblast monolayers via the CD44 receptor

    International Nuclear Information System (INIS)

    Ito, Gen; Kobayashi, Takeshi; Takeda, Yoshie; Sokabe, Masahiro

    2015-01-01

    Highlights: • Proteoglycan from salmon nasal cartridge (SNC-PG) promoted wound healing in fibroblast monolayers. • SNC-PG stimulated both cell proliferation and cell migration. • Interaction between chondroitin sulfate-units and CD44 is responsible for the effect. - Abstract: Proteoglycans (PGs) are involved in various cellular functions including cell growth, adhesion, and differentiation; however, their physiological roles are not fully understood. In this study, we examined the effect of PG purified from salmon nasal cartilage (SNC-PG) on wound closure using tissue-cultured cell monolayers, an in vitro wound-healing assay. The results indicated that SNC-PG significantly promoted wound closure in NIH/3T3 cell monolayers by stimulating both cell proliferation and cell migration. SNC-PG was effective in concentrations from 0.1 to 10 μg/ml, but showed much less effect at higher concentrations (100–1000 μg/ml). The effect of SNC-PG was abolished by chondroitinase ABC, indicating that chondroitin sulfates (CSs), a major component of glycosaminoglycans (GAGs) in SNC-PG, are crucial for the SNC-PG effect. Furthermore, chondroitin 6-sulfate (C-6-S), a major CS of SNC-PG GAGs, could partially reproduce the SNC-PG effect and partially inhibit the binding of SNC-PG to cells, suggesting that SNC-PG exerts its effect through an interaction between the GAGs in SNC-PG and the cell surface. Neutralization by anti-CD44 antibodies or CD44 knockdown abolished SNC-PG binding to the cells and the SNC-PG effect on wound closure. These results suggest that interactions between CS-rich GAG-chains of SNC-PG and CD44 on the cell surface are responsible for the SNC-PG effect on wound closure

  9. Proteoglycan from salmon nasal cartridge promotes in vitro wound healing of fibroblast monolayers via the CD44 receptor

    Energy Technology Data Exchange (ETDEWEB)

    Ito, Gen; Kobayashi, Takeshi; Takeda, Yoshie [Department of Physiology, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550 (Japan); Sokabe, Masahiro, E-mail: msokabe@med.nagoya-u.ac.jp [Department of Physiology, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550 (Japan); Mechanobiology Laboratory, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550 (Japan); Mechanobiology Institute Singapore, National University of Singapore, Singapore 117411 (Singapore)

    2015-01-16

    Highlights: • Proteoglycan from salmon nasal cartridge (SNC-PG) promoted wound healing in fibroblast monolayers. • SNC-PG stimulated both cell proliferation and cell migration. • Interaction between chondroitin sulfate-units and CD44 is responsible for the effect. - Abstract: Proteoglycans (PGs) are involved in various cellular functions including cell growth, adhesion, and differentiation; however, their physiological roles are not fully understood. In this study, we examined the effect of PG purified from salmon nasal cartilage (SNC-PG) on wound closure using tissue-cultured cell monolayers, an in vitro wound-healing assay. The results indicated that SNC-PG significantly promoted wound closure in NIH/3T3 cell monolayers by stimulating both cell proliferation and cell migration. SNC-PG was effective in concentrations from 0.1 to 10 μg/ml, but showed much less effect at higher concentrations (100–1000 μg/ml). The effect of SNC-PG was abolished by chondroitinase ABC, indicating that chondroitin sulfates (CSs), a major component of glycosaminoglycans (GAGs) in SNC-PG, are crucial for the SNC-PG effect. Furthermore, chondroitin 6-sulfate (C-6-S), a major CS of SNC-PG GAGs, could partially reproduce the SNC-PG effect and partially inhibit the binding of SNC-PG to cells, suggesting that SNC-PG exerts its effect through an interaction between the GAGs in SNC-PG and the cell surface. Neutralization by anti-CD44 antibodies or CD44 knockdown abolished SNC-PG binding to the cells and the SNC-PG effect on wound closure. These results suggest that interactions between CS-rich GAG-chains of SNC-PG and CD44 on the cell surface are responsible for the SNC-PG effect on wound closure.

  10. A comparison of surface topography characterization technologies for use in comparing spent bullet and cartridge case signatures

    Energy Technology Data Exchange (ETDEWEB)

    Batishko, C.R.; Hickman, B.J.; Cuta, F.M.

    1992-11-01

    The Pacific Northwest Laboratory was tasked by the US Department of Energy to provide technical assistance to the Federal Bureau of Investigation in evaluating and ranking technologies potentially useful in high-speed comparison of unique spent bullet and cartridge case surface signatures. Information sources included vendor input, current relevant literature, vendor phone contacts, other FBI resources, relevant PNL reports, and personal contact with numerous PNL technical staff. A comprehensive list of technologies was reduced to a list of 38 by grouping very similar methodologies, and further reduced to a short list of six by applying a set of five minimum functional requirements. A total of 14 primary criteria, many having secondary criteria, were subsequently used to evaluate each technology. The ranked short list results are reported and supported in this document, and their scores normalized to a hypothetical ideal system are as follows: (1) confocal microscopy 82.13; (2) laser dynamic focusing 72.04; (3)moire interferometry V70.94; (4)fringe field capacitance;(5)laser triangulation 66.18; (6)structured/sectioned light 65.55. Information available within the time/budget constraints which was used for the evaluation and ranking was not sufficiently detailed to evaluate specific implementations of the technologies. Each of the technologies in the short list was judged potentially capable of meeting the minimum requirements. Clever, novel engineering solutions resulting in a more cost-effective system, or a closer fit to the ``ideal system,`` could result in a reordering of the short list when actual technical proposals are evaluated. Therefore, it is recommended that a Request for Proposal not be limited to only the highest ranked technology, but include all six technologies in the short list.

  11. A comparison of surface topography characterization technologies for use in comparing spent bullet and cartridge case signatures

    Energy Technology Data Exchange (ETDEWEB)

    Batishko, C.R.; Hickman, B.J.; Cuta, F.M.

    1992-11-01

    The Pacific Northwest Laboratory was tasked by the US Department of Energy to provide technical assistance to the Federal Bureau of Investigation in evaluating and ranking technologies potentially useful in high-speed comparison of unique spent bullet and cartridge case surface signatures. Information sources included vendor input, current relevant literature, vendor phone contacts, other FBI resources, relevant PNL reports, and personal contact with numerous PNL technical staff. A comprehensive list of technologies was reduced to a list of 38 by grouping very similar methodologies, and further reduced to a short list of six by applying a set of five minimum functional requirements. A total of 14 primary criteria, many having secondary criteria, were subsequently used to evaluate each technology. The ranked short list results are reported and supported in this document, and their scores normalized to a hypothetical ideal system are as follows: (1) confocal microscopy 82.13; (2) laser dynamic focusing 72.04; (3)moire interferometry V70.94; (4)fringe field capacitance;(5)laser triangulation 66.18; (6)structured/sectioned light 65.55. Information available within the time/budget constraints which was used for the evaluation and ranking was not sufficiently detailed to evaluate specific implementations of the technologies. Each of the technologies in the short list was judged potentially capable of meeting the minimum requirements. Clever, novel engineering solutions resulting in a more cost-effective system, or a closer fit to the ideal system,'' could result in a reordering of the short list when actual technical proposals are evaluated. Therefore, it is recommended that a Request for Proposal not be limited to only the highest ranked technology, but include all six technologies in the short list.

  12. Radiation induced synthesis of In{sub 2}O{sub 3} nanoparticles - Part II: Synthesis of In{sub 2}O{sub 3} nanoparticles by thermal decomposition of un-irradiated and γ-irradiated indium acetylacetonate

    Energy Technology Data Exchange (ETDEWEB)

    Al-Resheedi, Ajayb Saud; Alhokbany, Norah Saad [Department of Chemistry, College of Science, King Saud University, KSU, (Saudi Arabia); Mahfouz, Refaat Mohammed, E-mail: rmhfouz@science.au.edu.eg [Chemistry Department, Faculty of Science, Assiut University, AUN, (Egypt)

    2015-09-15

    Pure cubic phase, In{sub 2}O{sub 3} nanoparticles with porous structure were synthesized by solid state thermal oxidation of un-irradiated and γ-irradiated indium acetyl acetonate in presence and absence of sodium dodecyl sulphate as surfactant. The as- synthesized In{sub 2}O{sub 3} nanoparticles were characterized by X-ray diffraction (XRD), fourier transformation infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), transition electron microscopy (TEM) and thermogravimetry (TG). The shapes and morphologies of as- synthesized In{sub 2}O{sub 3} nanoparticles were highly affected by γ-irradiation of indium acetyl acetonate precursor and by addition of sodium dodecyl sulphate as surfactant. Calcination of un-irradiated indium acetyl acetonate precursor to 4 hours of 600 °C leads to the formation of spherical- shaped accumulative and merged In{sub 2}O{sub 3} nanoparticles with porous structure, whereas irregular porous architectures composed of pure In{sub 2}O{sub 3} nanoparticles were obtained by using γ-irradiated indium acetylacetonate precursor. The as- prepared In{sub 2}O{sub 3} nano products exhibit photoluminescence emission (PL) property and display thermal stability in a wide range of temperature (25-800 °C) which suggest possible applications in nanoscale optoelectronic devices. (author)

  13. The influence of Boron on creep-rupture behaviour of austenitic unstabilized and Nb-stabilized stainless steel X8CrNi 1613 in unirradiated and irradiated condition

    International Nuclear Information System (INIS)

    Sen, Susant Kumar.

    1976-10-01

    The present study deals with influence of boron on creep-rupture behaviour in unirradiated condition at 650 0 C along with precipitation behaviour, heat-treatment and recrystallization of unstabilized and stabilized steel. The results of creep-rupture tests on unirradiated specimens show that boron exerts a beneficial effect on the rupture life and ductility. Boron losses its beneficial effect on creep properties in unstabilized steel by prolong creeping. The magnitude of beneficial effect of Boron on creep properties depends upon the initial boron distribution which influences the number, size and distribution of the precipitates. Boron promotes the precipitation of type M 23 C 6 Carbides in the grain as well as at the grain boundary. Boron segregates in atomic form during slow cooling from austenitizing temperature. The recrystallization will be delayed by the presence of boron. The results of creep tests at 650 0 C shows that boron exerts a beneficial effect on creep life of irradiated steels. (orig./GSC) [de

  14. Type-specific detection of high-risk human papillomavirus (HPV) in self-sampled cervicovaginal cells applied to FTA elute cartridge.

    Science.gov (United States)

    Gustavsson, Inger; Sanner, Karin; Lindell, Monica; Strand, Anders; Olovsson, Matts; Wikström, Ingrid; Wilander, Erik; Gyllensten, Ulf

    2011-08-01

    Most procedures for self-sampling of cervical cells are based on liquid-based media for transportation and storage. An alternative is to use a solid support, such as dry filter paper media. To evaluate if self-sampling of cervicovaginal fluid using a cytobrush (Viba-brush; Rovers Medical Devices B.V., Oss, The Netherlands) and a solid support such as the Whatman Indicating FTA Elute cartridge (GE Healthcare, United Kingdom) can be used for reliable typing of human papillomavirus (HPV), as compared to cervical samples obtained by a physician using a cytobrush and the indicating FTA Elute Micro card and biopsy analysis. A total of 50 women with a previous high-risk (HR) HPV positive test were invited to perform self-sampling using the Viba-brush and the FTA cartridge and thereafter a physician obtained a cervical sample using the cytobrush and a FTA card, together with a cervical biopsy for histology and HPV typing. Detection of HR-HPV types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58 and 59 was performed using three multiplex real-time polymerase chain reaction (PCR) assays. All samples contained sufficient amounts of genomic DNA and the self-samples yielded on average 3.5 times more DNA than those obtained by the physician. All women that were positive for HR-HPV in the biopsy sample also typed positive both by self-sampling and physician-obtained sampling. For women with a histological diagnosis of cervical intraepithelial neoplasia grades 2-3 (CIN 2-3) all three HPV samples showed 100% concordance. A higher number of women were HPV positive by self-sampling than by physician-obtained sampling or by biopsy analysis. The Viba-brush and the FTA cartridge are suitable for self-sampling of vaginal cells and subsequent HR-HPV typing. Copyright © 2011 Elsevier B.V. All rights reserved.

  15. Comparison of the Usefulness of SPE Cartridges for the Determination of β-Blockers and β-Agonists (Basic Drugs in Environmental Aqueous Samples

    Directory of Open Access Journals (Sweden)

    Magda Caban

    2015-01-01

    Full Text Available Even though the methodology used for the determination of β-blockers and β-agonists in environmental samples is based mainly on solid-phase extraction (SPE and gas chromatography or liquid chromatography with mass spectrometric detection, the available literature data on the applied SPE procedures is rather sparse. In this paper such comparison is presented. Moreover, the usefulness of the eight SPE cartridges for the determination of five β-blockers (acebutolol, atenolol, metoprolol, nadolol, and propranolol and two β-agonists (salbutamol and terbutaline in environmental aqueous samples using GC techniques is tested. Among them, three (the trifunction sorbent Strata Screen C, the copolymers LiChrolut EN, and the functionalized copolymer Isolute ENV+ were used for the first time for this purpose. It was confirmed that polystyrene-divinylbenzene-N-vinylpyrrolidone copolymers (PS-DVB-VP, Strata-X, and Oasis HLB cartridges have a better potential than a cation-exchange sorbent for the extraction of the target drugs from environmental water samples. However, it should be stressed out that the direct application of the tested SPE conditions for the analysis of real environmental water samples is not possible, and such parameters, like volume of loading sample, appropriate solvents for washing and elution steps, and so forth, must be optimized again in order to achieve satisfactory recovery values for the target compounds.

  16. Molecularly imprinted polymer cartridges coupled on-line with high performance liquid chromatography for simple and rapid analysis of dextromethorphan in human plasma samples.

    Science.gov (United States)

    Moein, Mohammad Mahdi; Javanbakht, Mehran; Akbari-Adergani, Behrouz

    2011-04-01

    In this paper, a novel method is described for automated determination of dextromethorphan in biological fluids using molecularly imprinted solid-phase extraction (MISPE) as a sample clean-up technique combined with high performance liquid chromatography (HPLC). The water-compatible molecularly imprinted polymers (MIPs) were prepared using methacrylic acid as functional monomer, ethylene glycol dimethacrylate as cross-linker, chloroform as porogen and dextromethorphan as template molecule. These imprinted polymers were used as solid-phase extraction sorbent for the extraction of dextromethorphan from human plasma samples. Various parameters affecting the extraction efficiency of the MIP cartridges were evaluated. The high selectivity of the sorbent coupled to the high performance liquid chromatographic system permitted a simple and rapid analysis of this drug in plasma samples with limits of detection (LOD) and quantification (LOQ) of 0.12 ng/mL and 0.35 ng/mL, respectively. The MIP selectivity was evaluated by analyzing of the dextromethorphan in presence of several substances with similar molecular structures and properties. Results from the HPLC analyses showed that the recoveries of dextromethorphan using MIP cartridges from human plasma samples in the range of 1-50 ng/mL were higher than 87%. Copyright © 2011 Elsevier B.V. All rights reserved.

  17. Rapid and simple detection of foot-and-mouth disease virus: Evaluation of a cartridge-based molecular detection system for use in basic laboratories.

    Science.gov (United States)

    Goller, K V; Dill, V; Madi, M; Martin, P; Van der Stede, Y; Vandenberge, V; Haas, B; Van Borm, S; Koenen, F; Kasanga, C J; Ndusilo, N; Beer, M; Liu, L; Mioulet, V; Armson, B; King, D P; Fowler, V L

    2018-04-01

    Highly contagious transboundary animal diseases such as foot-and-mouth disease (FMD) are major threats to the productivity of farm animals. To limit the impact of outbreaks and to take efficient steps towards a timely control and eradication of the disease, rapid and reliable diagnostic systems are of utmost importance. Confirmatory diagnostic assays are typically performed by experienced operators in specialized laboratories, and access to this capability is often limited in the developing countries with the highest disease burden. Advances in molecular technologies allow implementation of modern and reliable techniques for quick and simple pathogen detection either in basic laboratories or even at the pen-side. Here, we report on a study to evaluate a fully automated cartridge-based real-time RT-PCR diagnostic system (Enigma MiniLab ® ) for the detection of FMD virus (FMDV). The modular system integrates both nucleic acid extraction and downstream real-time RT-PCR (rRT-PCR). The analytical sensitivity of this assay was determined using serially diluted culture grown FMDV, and the performance of the assay was evaluated using a selected range of FMDV positive and negative clinical samples of bovine, porcine and ovine origin. The robustness of the assay was evaluated in an international inter-laboratory proficiency test and by deployment into an African laboratory. It was demonstrated that the system is easy to use and can detect FMDV with high sensitivity and specificity, roughly on par with standard laboratory methods. This cartridge-based automated real-time RT-PCR system for the detection of FMDV represents a reliable and easy to use diagnostic tool for the early and rapid disease detection of acutely infected animals even in remote areas. This type of system could be easily deployed for routine surveillance within endemic regions such as Africa or could alternatively be used in the developed world. © 2017 The Authors. Transboundary and Emerging Diseases

  18. Tensile properties of unirradiated path A PCA

    International Nuclear Information System (INIS)

    Braski, D.N.; Maziasz, P.J.

    1983-01-01

    The tensile properties of PCA in the Al (solution annealed), A3 (25%-cold worked), and B2 (aged, cold worked, and reaged) conditions were determined from room temperature to 600 0 C. The tensile behavior of PCA-A1 and -A3 was generally similar to that of titanium-modified type 316 stainless steel with similar microstructures. The PCA-B2 was weaker than PCA-A3, especially above 500 0 C, but demonstrated slightly better ducility

  19. Truck accident involving unirradiated nuclear fuel

    International Nuclear Information System (INIS)

    Carlson, R.W.; Fischer, L.E.

    1992-07-01

    In the early morning of Dec. 16, 1991, a severe accident occurred when a passenger vehicle traveling in the wrong direction collided with a tractor trailer carrying 24 nuclear fuel assemblies in 12 containers on Interstate 1-91 in Springfield, Massachusetts. This paper documents the mechanical circumstances of the accident and the physical environment to which the containers were exposed and the response of the containers and their contents. The accident involved four impacts where the truck was struck by the car, impacted on the center guardrail, impacted on the outer concrete barrier and came to rest against the center guardrail. The impacts were followed by a fire that began in the engine compartment, spread to the.tractor and cab, and eventually spread to the trailer and payload. The fire lasted for about three hours and the packages were involved in the fire for about two hours. As a result of the fire, the tractor-trailer was completely destroyed and the packages were exposed to flames with temperatures between 1300 degrees F and 1800 degrees F. The fuel assemblies remained intact during the accident and there was no release of any radioactive material during the accident. This was a very severe accident; however, the injuries were minor and at no time was the public health and safety at risk

  20. Dissolution rates of unirradiated UO{sub 2}, UO{sub 2} doped with {sup 233}U, and spent fuel under normal atmospheric conditions and under reducing conditions using an isotope dilution method

    Energy Technology Data Exchange (ETDEWEB)

    Ollila, Kaija [VTT Processes, Helsinki (Finland); Albinsson, Yngve [Chalmers Univ. of Technology, Goeteborg (Sweden); Oversby, Virginia [VMO Konsult, Stockholm (Sweden); Cowper, Mark [AEA Technology, Harwell (United Kingdom)

    2003-10-01

    The experimental results given in this report allow us to draw the following conclusions. 1) Tests using unirradiated fuel pellet materials from two different manufacturers gave very different dissolution rates under air atmosphere testing. Tests for fragments of pellets from different pellets made by the same manufacturer gave good agreement. This indicates that details of the manufacturing process have a large effect on the behavior of unirradiated UO{sub 2} in dissolution experiments. Care must be taken in interpreting differences in results obtained in different laboratories because the results may be affected by manufacturing effects. 2) Long-term tests under air atmosphere have begun to show the effects of precipitation. Further testing will be needed before the samples reach steady state. 3) Testing of unirradiated UO{sub 2} in systems containing an iron strip to produce reducing conditions gave [U] less than detection limits (<0.02 ppb) after a few days to a few weeks of testing. Uranium recovered from the rinsing of reaction vessels and from acid stripping of vessels was shown to be from dissolution of grains of solid dislodged when the samples were handled after the tests were terminated. 4) Batch tests conducted under reducing conditions showed evidence of colloidal material in the early solution samples. 5) In the batch tests, measurements taken at day 3 and day 5 show that precipitation occurs from day 3 to day 5 without any further dissolution of the solid. 6) At termination of the batch tests, all but one sample had [U] in solution less than detection limits (< 0.02 ppb). Materials recovered in test termination samples showed evidence for recovery of small amounts - amounts corresponding to that expected from a few grains of 5 to 10 {mu}m size - in the acidified solution samples. These are interpreted to have been dislodged during sample handling operations. 7) Batch test data show that increasing test duration beyond 2 weeks does not provide

  1. Penetrating chest trauma caused by a blank cartridge actuated rubber ball projectile: case presentation and ballistic investigation of an uncommon weapon type.

    Science.gov (United States)

    Frank, Matthias; Peters, Dieter; Klemm, Wolfram; Grossjohann, Rico; Ekkernkamp, Axel; Bockholdt, Britta; Seifert, Julia

    2017-09-01

    Recently, an increasing number of an uncommon weapon type based on a caliber 6-mm Flobert blank cartridge actuated revolver which discharges 10-mm-diameter rubber ball projectiles has been confiscated by police authorities following criminal offenses. A recent trauma case presenting with a penetrating chest injury occasioned an investigation into the basic ballistic parameters of this type of weapon. Kinetic energy E of the test projectiles was calculated between 5.8 and 12.5 J. Energy density ED of the test projectiles was close to or higher than the threshold energy density of human skin. It can be concluded that penetrating skin injuries due to free-flying rubber ball projectiles discharged at close range cannot be ruled out. However, in case of a contact shot, the main injury potential of this weapon type must be attributed to the high energy density of the muzzle gas jet which may, similar to well-known gas or alarm weapons, cause life-threatening or even lethal injuries.

  2. Quantitative method of viral pollution determination for large volume of water using ferric hydroxide gel impregnated on the surface of glassfibre cartridge

    Directory of Open Access Journals (Sweden)

    Akira Homma

    1974-01-01

    Full Text Available Quantitative method of viral pollution determination for large volume of water using ferric hydroxide gel impregnated on the surface of glassfibre cartridge filter. The use of ferric hydroxide gel, impregnated on the surface of glassfibre cartridge filter enable us to recover 62.5% of virus (Poliomylitis type I, Lsc strain exsogeneously added to 400 liters of tap-water. The virus concentrator system consists of four cartridge filters, in which the three first one are clarifiers, where the contaminants are removed physically, without significant virus loss at this stage. The last cartridge filter is impregnated with ferric hydroxide gel, where the virus is adsorbed. After the required volume of water has been processed, the last filter is removed from the system and the viruses are recovered from the gel, using 1 liter of glycine/NaOH buffer, at pH 11. Immediately the eluate is clarified through series of cellulose acetate membranes mounted in a 142mm Millipore filter. For the second step of virus concentration, HC1 1N is added slowly to the eluate to achieve pH 3.5-4. MgC1, is added to give a final concentration of 0.05M and the viruses are readsorbed on a 0.45 , porosity (HA cellulose acetate membrane, mounted in a 90 mm Millipore filter. The viruses are recovered using the same eluent plus 10% of fetal calf serum, to a final volume of 3 ml. In this way, it was possible to concentrate virus from 400 liters of tap-water, into 1 liter in the first stage of virus concentration and just to 3 ml of final volume in a second step. The efficiency, simplicity and low operational cost, provded by the method, make it feasible to study viral pollution of recreational and tap-water sources.Relata-se o emprego de um concentrador portátil, o qual se mostrou capaz de recuperar 62,5% dos vírus (Polio I, amostra Lsc experimentalmente dispersos em 400 litros de água, os quais foram reduzidos a 3 ml. O sistema concentrador de vírus é composto de quatro

  3. Award of two contracts for the renting of magnetic tape drives and tape libraries for LHC data storage and the purchase of the associated tape cartridges

    CERN Document Server

    2005-01-01

    This document concerns the award of two contracts for the renting and possible subsequent purchase of magnetic tape drives and tape libraries for LHC data storage. The Finance Committee is invited to agree to the procedure described in section 3 of this document for the evaluation and possible subsequent purchase of tape drives and tape libraries for the storage of data from the LHC experiments. Subject to approval of this procedure, the Finance Committee is further invited to approve the negotiation of a contract for the renting of tape drives and tape libraries for evaluation purposes from IBM, for an amount of 579 707 Swiss francs, and from StorageTek, for an amount of 472 297 Swiss francs, during the period January 2006 â?" March 2007, plus the purchase of the associated tape cartridges for amounts of 202 500 Swiss francs and 284 748 Swiss francs respectively. The Finance Committee will be informed of the results of the evaluation by the end of 2006 and, subject to the outcome, will be invited to approve...

  4. A Method for Multiple Mycotoxin Analysis in Wines by Solid Phase Extraction and Multifunctional Cartridge Purification, and Ultra-High-Performance Liquid Chromatography Coupled to Tandem Mass Spectrometry

    Science.gov (United States)

    Tamura, Masayoshi; Takahashi, Ayumi; Uyama, Atsuo; Mochizuki, Naoki

    2012-01-01

    An analytical method using two solid phase extractions and ultra-high-performance liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS) was developed for the identification and quantification of 14 mycotoxins (patulin, deoxynivalenol, aflatoxins B1, B2, G1, G2, M1, T-2 toxin, HT-2 toxin, zearalenone, fumonisins B1, B2, B3, and ochratoxin A) in domestic and imported wines. Mycotoxins were purified with an Oasis HLB cartridge, followed by a MultiSepTM #229 Ochra. As a result, sufficient removal of the pigments and highly polar matrices from the red wines was achieved. UHPLC conditions were optimized, and 14 mycotoxins were separated in a total of 13 min. Determinations performed using this method produced high correlation coefficients for the 14 mycotoxins (R > 0.990) and recovery rates ranging from 76 to 105% with good repeatability (relative standard deviation RSD < 12%). Twenty-seven samples of domestic and imported wines were analyzed using this method. Although ochratoxin A (OTA) and fumonisins (FMs) were detected in several samples, the FM levels were less than limits of quantification (LOQs) (1 μg/L), and even the largest of the OTA levels was below the EU regulatory level (2 μg/L). These results suggest that the health risk posed to consumers from the wines available in Japan is relatively low. PMID:22822458

  5. Combining selection valve and mixing chamber for nanoflow gradient generation: Toward developing a liquid chromatography cartridge coupled with mass spectrometer for protein and peptide analysis.

    Science.gov (United States)

    Chen, Apeng; Lu, Joann J; Gu, Congying; Zhang, Min; Lynch, Kyle B; Liu, Shaorong

    2015-08-05

    Toward developing a micro HPLC cartridge, we have recently built a high-pressure electroosmotic pump (EOP). However, we do not recommend people to use this pump to deliver an organic solvent directly, because it often makes the pump rate unstable. We have experimented several approaches to address this issue, but none of them are satisfactory. Here, we develop an innovative approach to address this issue. We first create an abruption (a dead-volume) within a fluid conduit. We then utilize an EOP to withdraw, via a selection valve, a train of eluent solutions having decreasing eluting power into the fluid conduit. When these solutions are further aspirated through the dead-volume, these solutions are partially mixed, smoothening concentration transitions between two adjacent eluent solutions. As these solutions are pushed back, through the dead-volume again, a smooth gradient profile is formed. In this work, we characterize this scheme for gradient formation, and we incorporate this approach with a high-pressure EOP, a nanoliter injection valve, and a capillary column, yielding a micro HPLC system. We then couple this micro HPLC with an electrospray ionization - mass spectrometer for peptide and protein separations and identifications. Copyright © 2015 Elsevier B.V. All rights reserved.

  6. SERS as an analytical tool in environmental science: The detection of sulfamethoxazole in the nanomolar range by applying a microfluidic cartridge setup.

    Science.gov (United States)

    Patze, Sophie; Huebner, Uwe; Liebold, Falk; Weber, Karina; Cialla-May, Dana; Popp, Juergen

    2017-01-01

    Sulfamethoxazole (SMX) is a commonly applied antibiotic for treating urinary tract infections; however, allergic reactions and skin eczema are known side effects that are observed for all sulfonamides. Today, this molecule is present in drinking and surface water sources. The allowed concentration in tap water is 2·10 -7  mol L -1 . SMX could unintentionally be ingested by healthy people when drinking contaminated tap water, representing unnecessary drug intake. To assess the quality of tap water, fast, specific and sensitive detection methods are required, in which consequence measures for improving the purification of water might be initiated in the short term. Herein, the quantitative detection of SMX down to environmentally and physiologically relevant concentrations in the nanomolar range by employing surface-enhanced Raman spectroscopy (SERS) and a microfluidic cartridge system is presented. By applying surface-water samples as matrices, the detection of SMX down to 2.2·10 -9  mol L -1 is achieved, which illustrates the great potential of our proposed method in environmental science. Copyright © 2016 Elsevier B.V. All rights reserved.

  7. Adsorption of various antimicrobial agents to endotoxin removal polymyxin-B immobilized fiber (Toraymyxin®). Part 2: Adsorption of two drugs to Toraymyxin PMX-20R cartridges.

    Science.gov (United States)

    Shimokawa, Ken-ichi; Takakuwa, Ryotaro; Wada, Yuko; Yamazaki, Noriko; Ishii, Fumiyoshi

    2013-01-01

    In our previous study, the degree of adsorption of 9 representative antimicrobial agents to Toraymyxin(®) PMX-F sheets was quantitatively evaluated. As a result, the adsorption rate was 22.1% for Linezolid in the presence of serum. Therefore, we investigated whether two types of antimicrobial agents (Ciprofroxacin and Linezolid) can be better adsorbed on PMX-F sheets. When the number of PMX-F sheets was increased in a step wise manner, specifically 2, 4, 6, 8 and 12, the adsorption rate increased linearly. In addition, the adsorption to polymyxin-B immobilized fiber (Toraymyxin(®) PMX-20R) cartridges, widely used to remove endotoxins from circulating blood in the treatment of sepsis, was quantitatively evaluated. As a result, in the presence of serum, Linezolid showed adsorption to PMX-20R, and the adsorption rate after 2h was 54.5%, and that after 4h was 65.8%. The results of this study suggest the necessity of monitoring blood antimicrobial concentration during treatment for sepsis with Linezolid, which showed adsorption to PMX-20R in an environment close to a clinical environment. Copyright © 2012 Elsevier B.V. All rights reserved.

  8. Community Laboratory Testing for Cryptosporidium: Multicenter Study Retesting Public Health Surveillance Stool Samples Positive for Cryptosporidium by Rapid Cartridge Assay with Direct Fluorescent Antibody Testing.

    Directory of Open Access Journals (Sweden)

    Dawn M Roellig

    Full Text Available Cryptosporidium is a common cause of sporadic diarrheal disease and outbreaks in the United States. Increasingly, immunochromatography-based rapid cartridge assays (RCAs are providing community laboratories with a quick cryptosporidiosis diagnostic method. In the current study, the Centers for Disease Control and Prevention (CDC, the Association of Public Health Laboratories (APHL, and four state health departments evaluated RCA-positive samples obtained during routine Cryptosporidium testing. All samples underwent "head to head" re-testing using both RCA and direct fluorescence assay (DFA. Community level results from three sites indicated that 54.4% (166/305 of Meridian ImmunoCard STAT! positives and 87.0% (67/77 of Remel Xpect positives were confirmed by DFA. When samples were retested by RCA at state laboratories and compared with DFA, 83.3% (155/186 of Meridian ImmunoCard STAT! positives and 95.2% (60/63 of Remel Xpect positives were confirmed. The percentage of confirmed community results varied by site: Minnesota, 39.0%; New York, 63.9%; and Wisconsin, 72.1%. The percentage of confirmed community results decreased with patient age; 12.5% of community positive tests could be confirmed by DFA for patients 60 years of age or older. The percentage of confirmed results did not differ significantly by sex, storage temperature, time between sample collection and testing, or season. Findings from this study demonstrate a lower confirmation rate of community RCA positives when compared to RCA positives identified at state laboratories. Elucidating the causes of decreased test performance in order to improve overall community laboratory performance of these tests is critical for understanding the epidemiology of cryptosporidiosis in the United States (US.

  9. Analytical and pre-analytical performance characteristics of a novel cartridge-type blood gas analyzer for point-of-care and laboratory testing.

    Science.gov (United States)

    Oyaert, Matthijs; Van Maerken, Tom; Bridts, Silke; Van Loon, Silvi; Laverge, Heleen; Stove, Veronique

    2018-03-01

    Point-of-care blood gas test results may benefit therapeutic decision making by their immediate impact on patient care. We evaluated the (pre-)analytical performance of a novel cartridge-type blood gas analyzer, the GEM Premier 5000 (Werfen), for the determination of pH, partial carbon dioxide pressure (pCO 2 ), partial oxygen pressure (pO 2 ), sodium (Na + ), potassium (K + ), chloride (Cl - ), ionized calcium ( i Ca 2+ ), glucose, lactate, and total hemoglobin (tHb). Total imprecision was estimated according to the CLSI EP5-A2 protocol. The estimated total error was calculated based on the mean of the range claimed by the manufacturer. Based on the CLSI EP9-A2 evaluation protocol, a method comparison with the Siemens RapidPoint 500 and Abbott i-STAT CG8+ was performed. Obtained data were compared against preset quality specifications. Interference of potential pre-analytical confounders on co-oximetry and electrolyte concentrations were studied. The analytical performance was acceptable for all parameters tested. Method comparison demonstrated good agreement to the RapidPoint 500 and i-STAT CG8+, except for some parameters (RapidPoint 500: pCO 2 , K + , lactate and tHb; i-STAT CG8+: pO 2 , Na + , i Ca 2+ and tHb) for which significant differences between analyzers were recorded. No interference of lipemia or methylene blue on CO-oximetry results was found. On the contrary, significant interference for benzalkonium and hemolysis on electrolyte measurements were found, for which the user is notified by an interferent specific flag. Identification of sample errors from pre-analytical sources, such as interferences and automatic corrective actions, along with the analytical performance, ease of use and low maintenance time of the instrument, makes the evaluated instrument a suitable blood gas analyzer for both POCT and laboratory use. Copyright © 2018 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  10. Clinical evaluation of high-risk HPV detection on self-samples using the indicating FTA-elute solid-carrier cartridge.

    Science.gov (United States)

    Geraets, D T; van Baars, R; Alonso, I; Ordi, J; Torné, A; Melchers, W J G; Meijer, C J L M; Quint, W G V

    2013-06-01

    High-risk human papillomavirus (hrHPV) testing in cervical screening is usually performed on physician-taken cervical smears in liquid-based medium. However, solid-state specimen carriers allow easy, non-hazardous storage and transportation and might be suitable for self-collection by non-responders in screening and in low-resource settings. We evaluated the adequacy of self-collected cervicovaginal (c/v) samples using a Viba-brush stored on an Indicating FTA-elute cartridge (FTA-based self-sampling) for hrHPV testing in women referred to a gynecology clinic due to an abnormal smear. 182 women accepted to self-collect a c/v sample. After self-sampling, a physician obtained a conventional liquid-based cervical smear. Finally, women were examined by colposcopy and a biopsy was taken when clinically indicated. Self-samples required only simple DNA elution, and DNA was extracted from physician-obtained samples. Both samples were tested for 14 hrHPVs by GP5+/6+-EIA-LQ Test and SPF(10)-DEIA-LiPA(25). Both assays detected significantly more hrHPV in physician-collected specimens than in self-collected samples (75.3% and 67.6% by SPF(10); 63.3% and 53.3% by GP5+/6+, respectively). The combination of physician-collected specimen and GP5+/6+ testing demonstrated the optimal balance in sensitivity (98.0%) and specificity (48.1%) for CIN2+ detection in this referral population. A test system of FTA-based self-collection and SPF(10) hrHPV detection approached this sensitivity (95.9%) and specificity (42.9%). These results show that the clinical performance of hrHPV detection is determined by both the sample collection system and the test method. FTA-based self-collection with SPF(10) testing might be valuable when a liquid-based medium cannot be used, but requires further investigation in screening populations. Copyright © 2013 Elsevier B.V. All rights reserved.

  11. [Determination of metformin hydrochloride, melamine and dicyandiamide in metformin hydrochloride preparations by tandem dual solid phase extraction cartridges-high performance liquid chromatography-electrospray ionization multi-stage mass spectrometry].

    Science.gov (United States)

    Zhou, Yanfen; Wang, Fanghuan; Wang, Zelan; Zhan, Haijuan; Liu, Wanyi; Meng, Zhe

    2018-02-08

    A method for the confirmation and quantification of metformin hydrochloride and its relative substances melamine and dicyandiamide using tandem dual solid phase extraction (SPE) cartridges and high performance liquid chromatography-electrospray ionization multi-stage mass spectrometry (HPLC-ESI-MS n ) was developed. The samples were extracted with anhydrous ethanol containing 0.1% (v/v) acetic acid under ultrasound-assisted conditions. The extracts were concentrated and purified using Cleanert PCX and C18 tandem dual solid phase extraction cartridges, and eluted with 5% (v/v) ammonia methanol solution. The separation was performed on a Kromasil-C18 column (100 mm×4.6 mm, 3.5 μm) with gradient elution. The detection was performed in selected ion monitoring (SIM) mode using electrospray ionization multi-stage mass spectrometry. The external standard method was used for quantification. The extraction solvents, types of SPE cartridges and eluents were optimized by comparing the recoveries under different conditions. The results showed that the detector response of each target compound was linear in corresponding mass concentration ranges with the correlation coefficients ( r 2 ) ≥ 0.9992. The limits of detection (LODs) and the limits of quantification (LOQs) of the three analytes were 1.48-13.61 μg/kg and 5.96-45.67 μg/kg, respectively. The recoveries of the three analytes were 65.02%-118.33% spiked at low, medium and high levels. The relative standard deviations (RSDs) were no more than 13.41%. The method is reliable, easy, and has a better purification effect. The method can be applied to the routine analysis of metformin hydrochloride and its relative substances melamine and dicyandiamide in different preparations of metformin hydrochloride.

  12. A Fully Automated Radiosynthesis of [18F]Fluoroethyl-Diprenorphine on a Single Module by Use of SPE Cartridges for Preparation of High Quality 2-[18F]Fluoroethyl Tosylate

    Directory of Open Access Journals (Sweden)

    Gjermund Henriksen

    2013-06-01

    Full Text Available We have developed a new method for automated production of 2-[18F]fluoroethyl tosylate ([18F]FETos that enables 18F-alkylation to provide PET tracers with high chemical purity. The method is based on the removal of excess ethylene glycol bistosylate precursor by precipitation and subsequent filtration and purification of the filtrate by means of solid phase extraction cartridges (SPE. The method is integrated to a single synthesis module and thereby provides the advantage over previous methods of not requiring HPLC purification, as demonstrated by the full radiosynthesis of the potent opioid receptor PET tracer [18F]fluoroethyldiprenorphine.

  13. Direct preparation of a graphene oxide modified monolith in a glass syringe as a solid-phase extraction cartridge for the extraction of quaternary ammonium alkaloids from Chinese patent medicine.

    Science.gov (United States)

    Liang, Xiaojing; Wang, Licheng; Wang, Shuai; Li, Yijing; Guo, Yong

    2017-11-01

    Packed cartridges have been widely used in solid-phase extraction. However, there are still some drawbacks, such as they are blocked easily and the method is time-consuming. In view of the advantages of monoliths, a monolithic extraction material has been directly synthesized in a glass syringe without any gap between the monolith and syringe inner wall. The monolithic syringe was modified with graphene oxide by loading graphene oxide dispersion onto it. The content of graphene oxide and the surface topography of the monolith have been evaluated by elemental analysis and scanning electron microscopy, respectively, which confirmed the successful modification. This prepared graphene oxide-modified monolithic syringe was directly used as a traditional solid-phase extraction cartridge. As expected, it shows good permeability and excellent capability for the extraction of quaternary ammonium alkaloids. The sample loading velocity (1-6 mL/min) does not affect the recovery. Under the optimal conditions, good linearities (R = 0.9992-0.9998) were obtained for five quaternary ammonium alkaloids, and the limits of detection and quantification were 0.5-1 and 1-2 μg/L, respectively. The proposed method was successfully applied for the analysis of quaternary ammonium alkaloids in Chinese patent medicine. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. Propagation of stress-corrosion cracks in unirradiated zircaloy

    International Nuclear Information System (INIS)

    Norring, K.; Haag, Y.; Wikstroem, C.

    1982-01-01

    Propagation of iodine-induced stress-corrosion cracks in Zircaloy was studied using pre-cracked and internally pressurized cladding tubes. These were recrystallized at different temperatures, to obtain grain sizes between 4 μm and 10 μm. No statistically significant difference in propagation rate due to the difference in grain size was observed. If the obtained data, with Ksub(I) values ranging from 4 to 11 MNmsup(-3/2), were log-log plotted (da/dt = CKsub(I)sup(N)), as usual, they fell within the scatter-band of data reported earlier. But from this plot it could also be seen that the Ksub(I) interval can be divided into two separate parts having different da/dt-Ksub(I) relations. The transition takes place at a Ksub(I) value of about 8 MNmsup(-3/2). The region with lower Ksub(I) values shows a substantially lower n value than the upper region (2.4 and 9.8 respectively), and earlier reported values (n = 7 to 10). This transition is in good agreement with a transition from an intergranular to a transgranular propagation mode of the stress-corrosion crack. (orig.)

  15. Reaction of unirradiated high-density fuel with aluminum

    International Nuclear Information System (INIS)

    Wiencek, T.C.; Meyer, M.K.; Prokofiev, I.G.; Keiser, D.D.

    1997-01-01

    Excellent dispersion fuel performance requires that fuel particles remain stable and do not react significantly with the surrounding aluminum matrix. A series of high-density fuels, which contain uranium densities >12 g/cm 3 , have been fabricated into plates. As part of standard processing, all of these fuels were subjected to a blister anneal of 1 h at 485 deg. C. Changes in plate thickness were measured and evaluated. From these results, suppositions about the probable irradiation properties of these fuels have been proposed. In addition, two fuels, U-10 wt% Mo and U 2 Mo, were subjected to various heat treatments and were found to be very stable in an aluminum matrix. On the basis of the experimental data, hypotheses of the irradiation behavior of these fuels are presented. (author)

  16. Plant-scale anodic dissolution of unirradiated IFR fuel pins

    International Nuclear Information System (INIS)

    Gay, E.C.; Tomczuk, Z.; Miller, W.E.

    1993-01-01

    This report discusses anodic dissolution which is a major operation in the pyrometallurgical process for recycling spent metal fuels from the Integral Fast Reactor (IFR), an advanced reactor design developed at Argonne National Laboratory. This process involves electrorefining the heavy metals (uranium and plutonium) from chopped, steel-clad fuel segments. The heavy metals are electrotransported from anodic dissolution baskets to solid and liquid cathodes in a molten salt electrolyte (LiCl-KCI) at 500 degrees C. Uranium is recovered on a solid cathode mandrel, while a uranium-plutonium mixture is recovered in a liquid cadmium cathode. The anode configuration consists of four baskets mounted on an anode shaft. These baskets provide parallel circuits in the electrolyte and salt flow through the chopped fuelbed as the baskets are rotated. The baskets for the engineering-scale tests were sized to contain up to 2.5 kg of heavy metal. Anodic dissolution of 10 kg batches of chopped, steel-clad simulated tuel (U-10% Zr and U-Zr-Fs alloy) was demonstrated

  17. Microstructure and mechanical properties of unirradiated low activation ferritic steel

    International Nuclear Information System (INIS)

    Hsu, C.Y.; Lechtenberg, T.A.

    1986-01-01

    Transmission electron micrographs of normalized and tempered 9Cr-2.5W-0.3V-0.15C low activation ferritic steel showed tempered lath-type martensite with precipitation of rod and plate-like carbides at lath and grain boundaries. X-ray diffraction analysis of the extracted replicas revealed nearly 100% M 23 C 6 carbides (a=1.064 nm), with no indication of Fe 2 W-type Laves phase even after thermal aging at 600 0 C/1000 h. Thermal aging increased the number density of rod-like M 23 C 6 along prior austenite grain boundaries and martensite lath boundaries. The elevated-temperature tensile strengths of this steel are about 10% higher than the average strengths of commercial heats of 9Cr-1Mo and modified 9Cr-1Mo steels up to 650 0 C, with equivalent uniform elongation and ∝50% decrease in total elongation. The DBTT was determined to be -25 0 C which is similar to other 9Cr-1Mo steels. Fractographic examination of tensile tested specimens shows a mixed mode of equiaxed and elongated dimples at test temperatures above 400 0 C. Modification of the Ga3X alloy composition for opimization of materials properties is discussed. However, the proposed low activation ferritic steel shows the promise of improved mechanical properties over 9Cr-1Mo steels. (orig.)

  18. Safety analysis report for packaging: the unirradiated fuel shipping container

    International Nuclear Information System (INIS)

    Evans, J.H.; Shipley, W.D.; Mouring, R.W.

    1979-09-01

    The container was evaluated analytically to determine its compliance with the applicable regulations governing containers in which radioactive and fissile materials are transported, and the evaluation is the subject of this report. Computational and test procedures were used to determine the structural integrity and thermal behavior of the container relative to the general standards for normal conditions of transport and the standards for hypothetical accident conditions. Results of the evaluation demonstrate that the container is in compliance with the applicable regulations

  19. High resolution X-ray diffraction studies on unirradiated

    Indian Academy of Sciences (India)

    High-resolution X-ray diffraction technique, employing a three-crystal monochromator–collimator combination is used to study the irradiation induced defects in flux grown Sr-hexaferrite crystals irradiated with 50 MeV Li3+ ion beams at room temperature with a fluence value of 1 × 1014 ions/cm2. The diffraction curves of the ...

  20. Unirradiated UO2 in irradiated zirconium alloy sheathing

    International Nuclear Information System (INIS)

    MacDonald, R.D.; Hardy, D.G.; Hunt, C.E.L.; Scoberg, J.A.

    1979-07-01

    Zircaloy-clad UO 2 fuel elements have defected in power reactors when element power outputs were raised significantly after a long irradiation at low power. We have irradiated fuel elements fabricated from fresh UO 2 pellets and zirconium alloy sheaths previously irradiated without fuel. This gave a fuel element with radiation-damaged low-ductility sheathing but with no fission products in the fuel. The elements were power boosted in-reactor to linear power outputs up to 84 kW/m for two five-day periods. No elements defected despite sheath strains of 0.82 percent at circumferential ridge postions. Half of these elements were subsequently soaked at low power to build up the fission product inventory in the fuel and then power boosted to 63 kW/m for a third time. Two elements defected on this final boost. We conclude that these defects were caused by fission product induced stress-corrosion cracking and that this mechanism plays an importent role in power reactor fuel defects. (auth)

  1. High temperature mechanical properties of unirradiated dispersion strengthened copper

    International Nuclear Information System (INIS)

    Gentzbittel, J.M.; Rigollet, C.; Robert, G.

    1994-01-01

    Oxide Dispersion Strengthened (ODS) copper material, due to its excellent thermal conductivity associated with a high temperature strength is a candidate material for structural applications as divertor plasma facing components of thermonuclear fusion reactor. Tensile and creep results of oxide dispersion strengthened copper are presented. The most important features of ODS copper high temperature behaviour are the high strength corresponding to low creep rates, high stress creep rate dependence, a poor ductility and a brittleness which result in a premature creep fracture at high applied stress. (R.P.) 2 refs.; 6 figs

  2. A study of the behaviour of irradiated or unirradiated grafts in the camera aquosa of irradiated and unirradiated animals

    International Nuclear Information System (INIS)

    Djalali-Behzad, G.

    1969-06-01

    Following grafts of new born mice spinal ganglia in the 'camera aquosa' of adult mice, the authors tried hematopoietic tissue grafts in the same conditions. The growth of iso-logous and hetero-logous bone marrow in the 'camera aquosa' showed that this tissue, even after exposure to supralethal doses, was capable of survival and growth. A counter-experiment with non irradiated bone marrow grafts in the 'camera aquosa' of rats delivered 700 rads led to the conclusion that the environment, intoxicated by exposure, acted on the graft so that after vascularization it became unable to grow. (author) [fr

  3. Indústria de cartucho de toner sob a ótica da remanufatura: estudo de caso de um processo de melhoria Remanufacturing of toner cartridge: a case study of a improvement process

    Directory of Open Access Journals (Sweden)

    Cícero Ferreira Fernandes Costa Filho

    2006-04-01

    Full Text Available Este trabalho apresenta um estudo de caso de um processo de melhoria aplicado a uma indústria de remanufatura de cartuchos de toner. Inicialmente, é feita uma abordagem do processo de remanufatura procurando salientar as principais características que o diferenciam de um processo de manufatura convencional e a importância do mesmo diante das preocupações ambientais atuais. Através de três indicadores de desempenho propostos no trabalho fez-se um diagnóstico do processo de remanufatura quanto ao aproveitamento de peças recolhidas do campo, atendimento de pedidos dos clientes e quantidade de defeitos. No diagnóstico inicial realizado, os valores obtidos para esses critérios situaram-se abaixo das metas estabelecidas na empresa. Através da metodologia PDCA, identificaram-se oportunidades de melhorias em pontos críticos do processo de fabricação. A implantação dessas melhorias resultou em ganhos nos indicadores de desempenho da ordem de 12%. Algumas ferramentas clássicas foram utilizadas para auxiliar na implementação da metodologia PDCA destacando-se brainstorming, diagrama de Ishikawa e Controle Estatístico de Processo.This paper presents an improvement process applied in one remanufacturing toner cartridge industry. It, initially, presents a mapping of the stages of this process by attempting to highlight the main characteristics, which distinguish it from a conventional manufacturing process and emphasizes its importance as an of eco-efficient process aiming at achieving sustainable development. Through three performance indicators proposed by the work, a diagnosis of the existing process was carried out as to the reuse of parts gasthered in the field, fulfilment of customers'orders and quantity of production faults. At the initial diagnosis carried out, the values obtained for theses criteria were located below the established targets proposed by the company. Through the PDCA tool, improvement opportunities in critical

  4. Nuclear Materials Management in a Recovery Facility for Unirradiated Enriched Uranium; Gestion des Matieres Nucleaires dans une Installation de Recuperation d'Uranium Enrichi Non Irradie; Administrativno-khozyajstvennyj uchet yadernykh materialov na ustanovke po regeneratsii neobluchennogo obogashchennogo urana; Administracion de Materiales Nucleares en una Planta de Recuperacion para Uranio Enriquecido No Irradiado

    Energy Technology Data Exchange (ETDEWEB)

    Jasny, G. R. [Union Carbide Corporation, Oak Ridge, TN (United States)

    1966-02-15

    The United States Atomic Energy Commission's Y-12 Plant, in Oak Ridge, Tennessee, has been processing and recovering various forms of unirradiated enriched uranium for over twenty years. Today, the Y-12 recovery facilities consist of a semi-continuous train of unit operations including dissolution, combustion, evaporation, extraction, denitration, and hydrofluorination. The processing and storage equipment is of restricted geometry and has a combined capacity of several hundred kilograms of enriched Uranium per month. Feed to the recovery operation comes both from the Plant and from other USAEC installations in the United States. This feed has included, at one time or another, practically every type of unirradiated enriched uranium scrap. Physical control is maintained successfully by the following techniques: 1. Careful design of equipment to permit cleaning and sampling and to minimize material trapping; 2. Continuous monitoring of all discards and waste streams including sewer and stack effluents and contaminated discards; 3. Periodic physical inventories; 4. Careful sampling and analysis of all external feed streams and product streams; 5. Stringent control of the quality of analytical measurements and of sampling; 6. Assignment of the responsibility for material control to operating personnel rather than to accounting personnel; 7. Careful indoctrination of operating personnel. Information input to the nuclear material accounting system is achieved by means of a paper flow closely paralleling the physical flow of material, i.e. batch identity is maintained by means of individual batch cards and batch disposition is signalled by transfer of the batch card to the nuclear material accounting department. Most accounting operations are performed on electronic data-processing equipment. In addition to the records and calculations required for material balances, historical records of hold-up and concentration are kept to detect anomalies in input-output or inventory

  5. 77 FR 11586 - Certain Toner Cartridges and Components Thereof

    Science.gov (United States)

    2012-02-27

    ...., Ltd., d/b/a Huebon Co., Limited, d/b/a Ink-Tank, 3/F, No. 1 Industrial Building, Pingdong 2 Road....V., Avenida del Parque 1175, Monterrey Technology Park, Cienega de Flores, Nuevo Leon, Mexico 65550...., 7611 Green Meadows Drive, Lewis Center, OH 43035. Discount Office Items, Inc., 302 Industrial Drive...

  6. 25MM Plastic Telescoped Cartridge Case Development Program

    Science.gov (United States)

    1975-01-01

    Mat’ I____ Projectile: 0wq. No. 30033;7,Rev, A, Platic "Band, 3000 Grain. Primer: Type .SmL. , Lot No.,, , Ne. . Flash Tubet.l3TSpe 1ell Project l...8217 _ ’_"__ Projectile: Dwg. No. 300347, Ray. A, Platic Biand, 3000 Graln. Primer: Type P-SIT.ML , Lot No. . No, Flash Tube:c<# 7’Tr-pecla1, Projectile Rot ntlo...Case: N ,o Rev. ___, Mati:.l, ILt Dwg. No,._____ Rev. M Nt l______Projectile: Dwg, No. 300347, ev • A, Platic ’ t -and, 3000 Grain, Primers Type , Lot

  7. Automated microfluidic cartridges for point-of-care cell counting

    CSIR Research Space (South Africa)

    Smith, S

    2016-10-01

    Full Text Available �PLFURIOXLGLF�FDUWULGJH�GHVLJQ� >�@�ZHUH�PDGH� WR�HQDEOH�DFFXUDWH�EORRG� VDPSOH�DQG�UHDJHQW�GLOXWLRQV�DQG�PL[LQJ�WR�EH�DFKLHYHG���)LJXUH���VKRZV�DQ�H[DPSOH�RI�WKH�LQMHFWLRQ� PROGHG�PLFURIOXLGLF�FDUWULGJH�ZLWK�EOLVWHU�SRXFKHV�XWLOL]HG�IRU�RQ�ERDUG�UHDJHQW�VWRUDJH��D���DV�ZHOO�DV� WKH�SRUWDEOH�VHW�XS...�����PL[LQJ�RI�VDPSOH�DQG�UHDJHQW��DQG����FKDPEHU�IRU�YLVXDOL]DWLRQ�DQG�FHOO�FRXQWLQJ����&DUWULGJH�GL� PHQVLRQV�� �����PP�î� �����PP�î� �PP�� �&DUWULGJHV� DQG� EOLVWHU� SRXFKHV�ZHUH�PDQXIDFWXUHG� E\\�PLFURIOXLGLF� &KLS6KRS�*PE+����E��'UDZLQJ�RI�SRUWDEOH�WHVW�VHW�XS�IRU�FRQWURO�DQG�WHVWLQJ�RI�PLFURIOXLGLF�FDUWULGJHV�� 978-0-9798064-9-0/µTAS 2016/$20©16CBMS...

  8. 21 CFR 520.1450b - Morantel tartrate cartridge.

    Science.gov (United States)

    2010-04-01

    ... grazing season. (2) Indications for use. For control of the adult stage of the following gastrointestinal... dosing gun to all cattle that will be grazing the same pasture. Effectiveness of the drug product is dependent upon continuous control of the gastrointestinal parasites for approximately 90 days following...

  9. Uranium and plutonium distribution in unirradiated mixed oxide fuel from industrial fabrication

    International Nuclear Information System (INIS)

    Hanus, D.; Kleykamp, H.

    1982-01-01

    Different process variants developed in the last few years by the firm ALKEM to manufacture FBR and LWR mixed oxide fuel are given. The uranium and plutonium distribution is determined on the pellets manufactured with the help of the electron beam microprobe. The stepwise improvement of the uranium-plutonium homogeneity in the short-term developed granulate variants and in the long-term developed new processes are illustrated starting with early standard processes for FBR fuel. An almost uniform uranium-plutonium distribution could be achieved for the long-term developed new processes (OKOM, AuPuC). The uranium-plutonium homogeneity are quantified in the pellets manufactured according to the considered process variants with a newly defined quality number. (orig.)

  10. The single SNR fuel assembly container (ESBB) to transport unirradiated SNR 300 fuel assemblies

    International Nuclear Information System (INIS)

    Hilbert, F.; Hottenrott, G.

    1998-01-01

    In this paper a new type B(U) package design is presented. The Single SNR Fuel Assembly Container (ESBB) is designed for the transport and storage of a single SNR 300 fuel assembly. This package is the main component for the future interim storage of the fuel assemblies in heavy storage casks. Its benefits are that it is compatible with the Category I transport system of Nuclear Cargo + Service NCS) used in Germany and that it can be easily handled at the current storage locations as well as in an interim storage facility. In total 205 fuel assemblies are currently stored in Hanau, Germany and Dounreay, U.K. Former studies have shown, that heavy transport and storage casks can be handled there only with considerable efforts. But the required category I transport to an interim storage is not reasonably feasible. To overcome these problems the ESBB was designed. It consists of a stainless steel tube with welded bottom, a welded plug as closure system and shock absorbers 26 packages at maximum can be transported in one batch with the NCS security vehicle. The safety analysis shows that the package complies with IAEA 1996. Standard calculations methods and computer codes like HEATING 7.2 (Childs 1993) have been used for the analysis. Criticality safety assessment is based on conservative assumptions as required in IAEA 1996. Drop tests carried out by BAM will be used to verify the design. These tests are scheduled for mid 1998. For the validation of the design prototypes have already been manufactured. Handling tests show that the design complies with the requirements. Preliminary drop tests show that the certification drop tests will be passed positively. (authors)

  11. Observations on the influence of tube manufacturing technique on iodine stress corrosion cracking of unirradiated Zircaloy

    International Nuclear Information System (INIS)

    Syrett, B.C.; Cubicciotti, D.; Jones, R.L.

    1979-01-01

    Closed-end tube pressurization tests at 593 K were used to compare the susceptibilities to iodine stress corrosion cracking (SCC) of two lots of Zircaloy-2 tubing manufactured by different suppliers. Although both tubings were produced to exactly the same specifications in terms of dimensions, chemical composition, burst strength, and certain other properties, as-received specimens from the two lots exhibited markedly different behavior in iodine SCC tests. The tubing from one supplier had a lower SCC threshold stress and failed about 30 times more quickly than the tubing from the other supplier. However, it was found that this difference in SCC susceptibility was eliminated if the internal surfaces of the specimens were polished to a 3 μm finish prior to testing. These observations are discussed in terms of possible effects of surface or near-surface chacteristics of the tubing on SCC susceptibility

  12. Fracture behavior of unirradiated HT-9 and modified 9Cr-1Mo welds

    International Nuclear Information System (INIS)

    Huang, F.H.; Gelles, D.S.

    1983-05-01

    Fracture toughness tests on HT-9 weld and HAZ samples and modified 9Cr-1Mo weld samples were performed at 93, 205, 427 and 538 0 C. Specimens were of circular compact tension type fabricated from welded material with the notch orientation parallel to the fusion line. The test results were analyzed using the J-integral approach. The results demonstrated that the toughness of HT-9 and 9Cr-1Mo was not significantly reduced due to welding. However, the tearing modulus of the welded material was lower than that of base metal, indicating that the alloys become less resistant to crack propagation as a result of welding

  13. Time of flight measurements of unirradiated and irradiated nuclear graphite under cyclic compressive load

    Energy Technology Data Exchange (ETDEWEB)

    Bodel, W., E-mail: william.bodel@hotmail.com [Nuclear Graphite Research Group, The University of Manchester (United Kingdom); Atkin, C. [Health and Safety Laboratory, Buxton (United Kingdom); Marsden, B.J. [Nuclear Graphite Research Group, The University of Manchester (United Kingdom)

    2017-04-15

    The time-of-flight technique has been used to investigate the stiffness of nuclear graphite with respect to the grade and grain direction. A loading rig was developed to collect time-of-flight measurements during cycled compressive loading up to 80% of the material's compressive strength and subsequent unloading of specimens along the axis of the applied stress. The transmission velocity (related to Young's modulus), decreased with increasing applied stress; and depending on the graphite grade and orientation, the modulus then increased, decreased or remained constant upon unloading. These tests were repeated while observing the microstructure during the load/unload cycles. Initial decreases in transmission velocity with compressive load are attributed to microcrack formation within filler and binder phases. Three distinct types of behaviour occur on unloading, depending on the grade, irradiation, and loading direction. These different behaviours can be explained in terms of the material microstructure observed from the microscopy performed during loading.

  14. Non-targeted mutagenesis of unirradiated lambda phage in Escherichia coli

    International Nuclear Information System (INIS)

    Wood, R.D.; Hutchinson, F.

    1984-01-01

    Non-targeted mutagenesis of lambda phage by ultraviolet light is the increase over background mutagenesis when non-irradiated phage are grown in irradiated Escherichia coli host cells. Such mutagenesis is caused by different processes from targeted mutagenesis, in which mutations in irradiated phage are correlated with photoproducts in the phage DNA. Non-irradiated phage grown in heavily irradiated uvr + host cells showed non-targeted mutations, which were 3/4 frameshifts, whereas targeted mutations were 2/3 transitions. For non-targeted mutagenesis in heavily irradiated host cells, there were one or two mutant phage per mutant burst. From the results of a series of experiments with various mutant host cells, a major pathway of non-targeted mutagenesis by ultraviolet light was proposed which acts in addition to ''SOS induction''. This pathway involves binding of the enzyme DNA polymerase I to damaged genomic DNA, and low polymerase activity leads to frameshift mutations during semiconservative DNA replication. The data suggest that this process will play a much smaller role in ultraviolet mutagenesis of the bacterial genome than it does in the mutagenesis of lambda phage. (author)

  15. Unirradiated characteristics of U-Si alloys as dispersed-phase fuels

    International Nuclear Information System (INIS)

    Domagala, R.F.; Wiencek, T.C.

    1987-06-01

    To satisfy the power demands of many research reactors, a new LEU fuel with a high density and U content was needed. Any fuel must be compatible with Al and its alloys so that it may be fabricable as a dispersed-phase in Al alloy and Al matrix plate-type elements following, as nearly as possible, established commercial manufacturing techniques. U-Si and U-Si-Al alloys at or near the composition of U 3 Si were immediately attractive because of work documented by the Canadians. 8 refs., 2 figs

  16. A discussion of possible mechanisms affecting fission product transport in irradiated and unirradiated nuclear grade graphite

    International Nuclear Information System (INIS)

    Firth, M.J.

    1977-09-01

    137 Cs, 85 Sr, and sup(110m)Ag adsorption experiments were conducted on three graphite powders with differing amounts of specific basal and edge surface areas. No direct proportionality was found between the specific amounts of the isotopes adsorbed and either of the surface characteristics. There appears to be some correlation with the specific basal surface area despite the fact that each isotope behaves differently. Factors that might influence the adsorption behaviour of Cs and Ag during reactor irradiation and heat treatment of nuclear grade graphites are discussed. These include the form of Cs with the graphite surface. A model based on Cs adsorption at vacancy clusters is used to analyse adsorption experiments. A possible explanation for the behaviour of Ag through the migration of graphite impurities from the bulk of the graphite to the pore surface is also discussed. (author)

  17. Tensile properties of unirradiated PCA from room temperature to 7000C

    International Nuclear Information System (INIS)

    Braski, D.N.; Maziasz, P.J.

    1983-01-01

    The tensile properties of Prime Candidate Alloy (PCA) austenitic stainless steel after three different thermomechanical treatments were determined from room temperature to 700 0 C. The solution-annealed PCA had the lowest strength and highest ductility, while the reverse was true for the 25%-cold-worked material. The PCA containing titanium-rich MC particles fell between the other two heats. The cold-worked PCA had nearly the same tensile properties as cold-worked type 316 stainless steel. Both alloys showed ductility minima at 300 0 C

  18. Non-targeted mutagenesis of unirradiated lambda phage in Escherichia coli

    Energy Technology Data Exchange (ETDEWEB)

    Wood, R.D.; Hutchinson, F. (Yale Univ., New Haven, CT (USA). Dept. of Molecular Biophysics and Biochemistry)

    1984-03-05

    Non-targeted mutagenesis of lambda phage by ultraviolet light is the increase over background mutagenesis when non-irradiated phage are grown in irradiated Escherichia coli host cells. Such mutagenesis is caused by different processes from targeted mutagenesis, in which mutations in irradiated phage are correlated with photoproducts in the phage DNA. Non-irradiated phage grown in heavily irradiated uvr/sup +/ host cells showed non-targeted mutations, which were 3/4 frameshifts, whereas targeted mutations were 2/3 transitions. For non-targeted mutagenesis in heavily irradiated host cells, there were one or two mutant phage per mutant burst. From the results of a series of experiments with various mutant host cells, a major pathway of non-targeted mutagenesis by ultraviolet light was proposed which acts in addition to ''SOS induction''. This pathway involves binding of the enzyme DNA polymerase I to damaged genomic DNA, and low polymerase activity leads to frameshift mutations during semiconservative DNA replication. The data suggest that this process will play a much smaller role in ultraviolet mutagenesis of the bacterial genome than it does in the mutagenesis of lambda phage.

  19. Thermogravimetric studies of the thermooxidative stability of irradiated and unirradiated polyethylene

    International Nuclear Information System (INIS)

    Gal, O.; Novakovic, Lj.; Stannett, V.T.

    1983-01-01

    The addition of antioxidants to polymers increases their thermooxidative stability as indicated by a delay and/or a retardation of degradation. The present paper considers the influence of the nature of the antioxidant (hindered phenols, aromatic amines, and organic compounds containing sulphur atoms) on the thermooxidative behaviour of a low density polyethylene at 200 deg C. The following characteristics have been measured in polymer samples with zero; 0.1; 0.5; and 1.0 wt% content of antioxidant: the induction time of the oxidation process, rate of autoxidation and rate of polymer degradation (up to about 20% weight loss). The difference in thermal stability in radiation crosslinked material and comparative retardation of the thermooxidative degradation is observed up to an absorbed dose of 200 kGy. (author)

  20. Thermogravimetric studies of the thermooxidative stability of irradiated and unirradiated polyethylene. Pt. 1. Effect of antioxidant

    Energy Technology Data Exchange (ETDEWEB)

    Gal, O; Novakovic, Lj [Institut za Nuklearne Nauke Boris Kidric, Belgrade (Yugoslavia); Stannett, V T [North Carolina State Univ., Raleigh (USA)

    1983-01-01

    The addition of antioxidants to polymers increases their thermooxidative stability as indicated by a delay and/or a retardation of degradation. The present paper considers the influence of the nature of the antioxidant (hindered phenols, aromatic amines, and organic compounds containing sulphur atoms) on the thermooxidative behaviour of a low density polyethylene at 200 deg C. The following characteristics have been measured in polymer samples with zero; 0.1; 0.5; and 1.0 wt% content of antioxidant: the induction time of the oxidation process, rate of autoxidation and rate of polymer degradation (up to about 20% weight loss). The difference in thermal stability in radiation crosslinked material and comparative retardation of the thermooxidative degradation is observed up to an absorbed dose of 200 kGy.

  1. White-matter abnormalities in unirradiated patients cured of primary central nervous system lymphoma

    International Nuclear Information System (INIS)

    Kim, L.; Hochberg, F.H.; Shaeffer, P.

    2000-01-01

    On MRI, primary brain tumors are commonly seen as contrast-enhancing masses surrounded by areas of abnormal signal on T2-weighted images. Following successful treatment tumors may no longer show contrast enhancement. The residual abnormalities are assumed to be represent ''edema'' and infiltrating tumor cells. We report nine patients with primary lymphoma of the central nervous system who had complete responses to intravenous methotrexate, but did not receive intrathecal chemotherapy or cranial irradiation. After complete resolution of contrast-enhancing lesions, persistent abnormalities on T2-weighted images in the region of prior tumor were initially assumed to reflect residual viable tumor. As they remained unchanged for years, however, this may not hold true in the cases in which primary central nervous system lymphoma responds to chemotherapy alone. (orig.)

  2. Storage of unirradiated fuel in borated concrete at the Savannah River Plant

    International Nuclear Information System (INIS)

    Honkonen, D.L.

    1979-06-01

    At the Savannah River Plant (SRP), more than 3000 enriched uranium fuel elements can be stored in horizontal holes in borated concrete racks. This method of storage was selected. This paper describes the largest of these racks and the reactivity calculations and measurements which confirmed that SRP fuel may be safely stored in them

  3. Proof tests of irradiated and unirradiated EBR-II subassembly ducts

    International Nuclear Information System (INIS)

    Ruther, W.E.; Chopra, P.S.; Lambert, J.D.B.

    1977-01-01

    A series of dynamic pressure tests have been conducted within EBR-II subassembly ducts. The tests were designed to simulate bursting of a driver-fuel element in a cluster of such elements at their burnup limit during off-normal conditions in EBR-II. The major objective of the tests was to assure that such failure, which might cause rapid release of stored fission gas, would not deform or otherwise damage subassembly ducts in a way that would hinder movement of a control rod. The test results are described

  4. Interaction between UO2 kernel and pyrocarbon coating in irradiated and unirradiated HTR fuel particles

    International Nuclear Information System (INIS)

    Drago, A.; Klersy, R.; Simoni, O.; Schrader, K.H.

    1975-08-01

    Experimental observations on unidirectional UO 2 kernel migration in TRISO type coated particle fuels are reported. An analysis of the experimental results on the basis of data and models from the literature is reported. The stoichiometric composition of the kernel is considered the main parameter that, associated with a temperature gradient, controls the unidirectional kernel migration

  5. Bioregulation of aflatoxin biosynthesis by unirradiated and irradiated conidia of Aspergillus flavus

    International Nuclear Information System (INIS)

    Aziz, N.H.; Abu-Shady, M.R.; El-Fouly, M.Z.; Moussa, L.A.

    1996-01-01

    A sequential technique involving the transfer of mycelia from peptone-based, aflatoxin-non-supporting medium to glucose based, aflatoxin-supporting medium was used to study the effect of γ-irradiation on the regulation of aflatoxin biosynthesis by Aspergillus flavus. Analysis indicated that irradiation at a dose of 1.00 kGy produced enhancement of aflatoxin biosynthesis in peptone-glucose mineral salt cultures with an increase of adenine nucleotide levels and fatty acid patterns of microsomes and mitochondria. The results suggest that aflatoxin synthesis is not regulated by the overall energy status of the fungal cell but that lipoperoxidation by γ-irradiation plays a role in aflatoxin biosynthesis

  6. Plastic flow properties and fracture toughness characterization of unirradiated and irradiated tempered martensitic steels

    International Nuclear Information System (INIS)

    Spaetig, P.; Bonade, R.; Odette, G.R.; Rensman, J.W.; Campitelli, E.N.; Mueller, P.

    2007-01-01

    We investigate the plastic flow properties at low and high temperature of the tempered martensitic steel Eurofer97. We show that below room temperature, where the Peierls friction on the screw dislocation is active, it is necessary to modify the usual Taylor's equation between the flow stress and the square root of the dislocation density and to include explicitly the Peierls friction stress in the equation. Then, we compare the fracture properties of the Eurofer97 with those of the F82H steel. A clear difference of the fracture toughness-temperature behavior was found in the low transition region. The results indicate a sharper transition for Eurofer97 than for the F82H. Finally, the shift of the median toughness-temperature curve of the F82H steel was determined after two neutron irradiations performed in the High Flux Reactor in Petten

  7. Metallurgical characteristics and fracture mechanical properties of unirradiated Kori-1 RPV weld: Linde 80, WF-233

    International Nuclear Information System (INIS)

    Hong, Jun Hwa; Lee, B. S.; Oh, Y. J.; Chi, S. H.; Kim, J. H.; Park, D. G.; Yoon, J. H.; Oh, J. M.

    2000-07-01

    The fracture toughness transition properties of the low upper shelf weld, Linde 80 WF-233, of Kori-1 RPV were evaluated by the master curve method, which is designated by ASTM E 1921, 'Standard test method for determination of reference temperature, T o , for ferritic steels in the transition range'. The reference temperature, T o =-83 deg C, was determined by PCVN specimens at -90 deg C. This value is similar to that of other high copper welds. The initial RT NDT was conservatively estimated as -26 deg F from the current fracture toughness results. From the studies on the chemistry and microstructure, the fracture mechanical properties of WF-233 weld is convincingly not worse than WF-70 and 72W welds

  8. Dissolution of unirradiated UO{sub 2} and UO{sub 2} doped with {sup 233}U under reducing conditions

    Energy Technology Data Exchange (ETDEWEB)

    Ollila, K. [VTT Processes (Finland); Oversby, V.M. [VMO Konsult (Sweden)

    2005-01-01

    Experiments have been conducted to determine an upper limit to the dissolution rate of UO{sub 2} under reducing conditions appropriate to those in a geologic repository for spent fuel disposal in Finland and Sweden. Test duration ranged from 52 to 140 days. The total amount of U recovered in each test was converted into a dissolution rate per year for the sample. The dissolution rate was then used to calculate an expected lifetime for the samples under the test conditions. The dissolution rate did not depend on the length of the testing period. Rather, the dissolution rate appeared to decrease as the samples were exposed to sequential testing periods. This indicates that the results are still influenced by transient effects such as high-energy surface sites, which implies that the dissolution rates measured are upper limits. The sample lifetimes calculated from the last two testing periods, which had a total of 269 days, ranged from 7 to 10 million years. There was no indication of an effect of alpha radiolysis on the dissolution rate results for samples with doping levels of 0, 5, and 10% {sup 233}U.

  9. Iodine stress corrosion cracking (SCC) of unirradiated Zircaloy-4 tubing by means of internal gas pressurization, (1)

    International Nuclear Information System (INIS)

    Onchi, Takeo; Inoue, Tadashi

    1982-01-01

    The internal gas pressurization tests were conducted at 360 0 C, to examine the influence of iodine concentration on the iodine stress corrosion cracking (SCC) susceptibility of Zircaloy-4 tubing of 17 x 17 type PWR design. The iodine contents studied were ranging of 0.06 to 6 mg/cm 2 , corresponding to 30 from 0.3 mg/cm 3 . Applied hoop stress vs. time-to-failure relationships were obtained in argon gas with iodine, as well as without iodine, from the tests of maximum holding times up to 72 hrs. The relationships obtained were insensitive to iodine contents. The applied stress lowering in iodine atmosphere approached a threshold stress below which SCC failure did not occur within the holding time, but not in argon gas alone. The threshold stresses were approximately 25.5 kg/mm 2 (250 Mpa), independent on iodine concentrations. Based on fracture mechanics approach and fractographic analysis, an interpretation was made of those applied stress and time-to-failure relationships. (author)

  10. Impact of creep-fatigue interaction on the lifetime of a dispersion strengthened copper alloy in unirradiated and irradiated conditions

    International Nuclear Information System (INIS)

    Singh, B.N.; Toft, P.; Stubbins, J.F.

    2001-06-01

    Creep-fatigue interaction behaviour of a dispersion strengthened copper alloy was investigated at 22 and 250 deg. C. To determine the effect of irradiation a number of fatigue specimens were irradiated at 250 deg. C to a dose level of 0.3 dpa and were tested at 250 deg. C. The creep-fatigue interaction was simulated by applying a certain hold-time on both tension and compression sides of the cyclic loading with a frequency of 0.5 Hz. Hold-times of 0,2, 5, 10, 100 and 1000 seconds were used. For a given hold-time, the real lifetime and the number of cycles to failure were determined at different strain amplitudes. Post-deformation micro-structures and fracture surfaces were investigated using transmission and scanning electron microscopes, respectively. The main results of these investigations are presented and their implications are briefly discussed in the present report. The central conclusion emerging from the present work is that a hold-time of 10 seconds or less causes a drastic decrease in the real lifetime as well as in the number of cycles to failure, particularly at low levels of strain amplitudes. A combination of higher temperature, higher strain amplitude and longer hold-time, on the other hand, may lead to an improvement in the lifetime. The irradiation at 250 deg. C to a dose level of 0.3 dpa does not play any significant role in determining the lifetime under creep-fatigue testing conditions. (au)

  11. Ductility and failure behaviour of both unirradiated and irradiated zircaloy-4 cladding using plane strain tensile specimens

    International Nuclear Information System (INIS)

    Carassou, S.; Le Saux, M.; Pizzanelli, J.P.; Rabouille, O.; Averty, X.; Poussard, C.; Cazalis, B.; Desquines, J.; Bernaudat, C.

    2010-01-01

    In this work, eight PST (Plan Strain Tensile) tests machined from a Zircaloy-4 (Zy-4) cladding irradiated up to 5 annual cycles have been performed at 280, 350 and 480 Celsius degrees. The specimen displacements during the tests were filmed and digitally recorded to allow the use of a Digital Image Correlation (DIC) analysis technique to experimentally determine the local strains on the outer surface of the specimens. The plane strain conditions have been verified and prevail over a wide area between the notches of the specimen, as expected from full 3D FE numerical analysis performed in support of the tests. For the first time, the location of the onset of fracture for this geometry on irradiated material has been experimentally observed: at 280 C.degrees, crack initiates in the vicinity of the notches, in an area where plane strain conditions are not fulfilled, and for a local circumferential strain value of about 5%. At 350 C. degrees and 480 C. degrees, cracks initiate at a location where plane strain conditions prevail, for circumferential strain values respectively close to 10% and greater than 50%. These results have been compared to results obtained previously by similar test on fresh and hydrided material, as well as tests performed as support to the study. At 350 C. degrees, the homogeneous 700 ppm hydrided Zy-4 and the Zy-4 irradiated during 5 annual cycles exhibit similar fracture behaviour, for both fracture hoop strain values (10%) and fracture mode (through-wall slant fracture). For the irradiated material, it has clearly been established that at 350 C. degrees, a brittle fracture occurs at the outer surface in the hydride rim. The crack propagates subsequently toward the inner surface and the notches, where final fracture occurs

  12. Field test and evaluation of the IAEA coincidence collar for the measurement of unirradiated BWR fuel assemblies

    International Nuclear Information System (INIS)

    Menlove, H.O.; Keddar, A.

    1982-12-01

    The neutron coincidence counter has been field tested and evaluated for the measurement of boiling-water-reactor (BWR) fuel assemblies at the ASEA-ATOM Fuel Fabrication Facility. The system measures the 235 U content per unit length of full fuel assemblies using neutron interrogation and coincidence counting. The 238 U content is measured in the passive mode without the AmLi neutron interrogatioin source. The field tests included both standard production movable fuel rods to investigate enrichment and absorber variations. Results gave a response standard deviation of 0.9% for the active case and 2.1% for the passive case in 1000-s measurement times. 10 figures, 2 tables

  13. The oxidative dissolution of unirradiated UO2 by hydrogen peroxide as a function of pH

    International Nuclear Information System (INIS)

    Clarens, F.; Pablo, J. de; Casas, I.; Gimenez, J.; Rovira, M.; Merino, J.; Cera, E.; Bruno, J.; Quinones, J.; Martinez-Esparza, A.

    2005-01-01

    The dissolution of non-irradiated UO 2 was studied as a function of both pH and hydrogen peroxide concentration (simulating radiolytic generated product). At acidic pH and a relatively low hydrogen peroxide concentration (10 -5 mol dm -3 ), the UO 2 dissolution rate decreases linearly with pH while at alkaline pH the dissolution rate increases linearly with pH. At higher H 2 O 2 concentrations (10 -3 mol dm -3 ) the dissolution rates are lower than the ones at 10 -5 mol dm -3 H 2 O 2 , which has been attributed to the precipitation at these conditions of studtite (UO 4 . 4H 2 O, which was identified by X-ray diffraction), together with the possibility of hydrogen peroxide decomposition. In the literature, spent fuel dissolution rates determined in the absence of carbonate fall in the H 2 O 2 concentration range 5 x 10 -7 - 5 x 10 -5 mol dm -3 according to our results, which is in agreement with H 2 O 2 concentrations determined in spent fuel leaching experiments

  14. Thermomechanical behavior and modeling of zircaloy cladding tubes from an unirradiated state to high burn-up

    International Nuclear Information System (INIS)

    Schaeffler-Le Pichon, I.; Geyer, P.; Bouffioux, P.

    1997-01-01

    Creep laws are nowadays commonly used to simulate the fuel rod response to the solicitations it faces during its life. These laws are sufficient for describing the base operating conditions (where only creep appears), but they have to be improved for power ramp conditions (where hardening and relaxation appear). The modification due to a neutronic irradiation of the thermomechanical behavior of stress-relieved Zircaloy 4 fuel tubes that have been analysed for five different fluences ranging from a non-irradiated material to a material for which the combustion rate was very high is presented. In the second part, a viscoplastic model able to simulate, for different isotherms, out-of-flux anisotropic mechanical behavior of the cladding tubes irradiated until high burn-up is proposed. Finally, results of numerical simulations show the ability of the model to reproduce the totality of the thermomechanical experiments. (author)

  15. Unirradiated cells rescue cells exposed to ionizing radiation: Activation of NF-κB pathway in irradiated cells

    Energy Technology Data Exchange (ETDEWEB)

    Lam, R.K.K. [Department of Physics and Materials Science, City University of Hong Kong (Hong Kong); Han, Wei [Center of Medical Physics and Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031 (China); Yu, K.N., E-mail: peter.yu@cityu.edu.hk [Department of Physics and Materials Science, City University of Hong Kong (Hong Kong); State Key Laboratory in Marine Pollution, City University of Hong Kong (Hong Kong)

    2015-12-15

    Highlights: • Rescue effect was observed in both irradiated and HeLa and NIH/3T3 cells. • Novel setup and procedures to separate the rescue signals and the bystander signals. • Confirmed activation of NF-κB pathway in rescue effect using activation inhibitor. • Confirmed activation of NF-κB pathway in rescue effect using anti-NF-κB p65 antibody. - Abstract: We studied the involvement of NF-κB pathway activation in the rescue effect in HeLa and NIH/3T3 cells irradiated by α particles. Firstly, upon irradiation by 5 cGy of α particles, for both cell lines, the numbers of 53BP1 foci/cell at 12 h post-irradiation were significantly smaller when only 2.5% of the cell population was irradiated as compared to 100% irradiation, which demonstrated the rescue effect. Secondly, we studied the effect of NF-κB on the rescue effect through the use of the NF-κB activation inhibitor BAY-11-7082. Novel experimental setup and procedures were designed to prepare the medium (CM) which had conditioned the bystander cells previously partnered with irradiated cells, to ensure physical separation between rescue and bystander signals. BAY-11-7082 itself did not inflict DNA damages in the cells or have effects on activation of the NF-κB response pathway in the irradiated cells through direct irradiation. The rescue effect was induced in both cell lines by the CM, which was abrogated if BAY-11-7082 was added to the CM. Thirdly, we studied the effect of NF-κB on the rescue effect through staining for phosphorylated NF-κB (p-NF-κB) expression using the anti-NF-κB p65 (phospho S536) antibody. When the fraction of irradiated cells dropped from 100% to 2.5%, the p-NF-κB expression in the cell nuclei of irradiated NIH/3T3 cells increased significantly, while that in the cell nuclei of irradiated HeLa cells also increased although not significantly. Moreover, the p-NF-κB expression in the cell nuclei of irradiated HeLa cells and NIH/3T3 cells treated with CM also increased significantly.

  16. Investigations of oxide particles in unirradiated ODS-Eurofer by TEM and 3D atom probe methods

    International Nuclear Information System (INIS)

    Aleev, A.A.; Iskandarov, N.A.; Nikitin, A.A.; Rogizhkin, S.V.; Zaluzhny, A.G.; Klimenkov, M.; Lindau, R.; Moeslang, A.; Vladimirov, P.

    2009-01-01

    Oxide dispersion strengthened steels possess better high-temperature creep and radiation resistance than conventionally produced ferritic/martensitic steels. This behavior is mainly caused by the presence of highly dispersed and extremely stable oxide particles with sizes of few nanometers. One of the promising oxides used for dispersion strengthening was yttria (Y 2 O 3 ), which was introduced into EUROFER by mechanical alloying followed by the hot isostatic pressing at temperature around 1000-1200 dg. C and pressure ∼100 MPa. It was found that mechanical properties were strongly depended on size and spatial distribution of the precipitates. Therefore considerable efforts are focused on the investigation of the chemical composition and orientation of precipitates with respect to the steel matrix. Recent studies of Eurofer ODS steel (9%-CrWVTa) by SANS revealed the presence of high number density structural features with a size of approximately one nanometer. At the same time, previous studies by TEM identified only high number of small (6-40 nm) Y 2 O 3 particles. In this work we tried to get a deeper inside into the nanostructure of this material by means of tomographic atom probe and to correlate the results with the picture obtained by TEM. The present investigations revealed fine (∼2 nm) enrichments containing not only yttrium and oxygen but also vanadium and nitrogen. Concentration of vanadium was found to be approximately at the same level as yttrium. Some of the enrichments contained only three or even two elements mentioned above. Estimated number density of enrichments is about (1/5) x 10 23 m -3 . We suppose that these enriched zones might be precursors of the larger precipitates observed by TEM. The thesis seems to be supported by the similarities of the chemical composition and spatial distribution of elements inside enriched zones and nano precipitates studied by atomic probe and analytical TEM methods. (author)

  17. Leaching action of EJ-13 water on unirradiated UO2 surfaces under unsaturated conditions at 90 degree C: Interim report

    International Nuclear Information System (INIS)

    Wronkiewicz, D.J.; Bates, J.K.; Gerding, T.J.; Veleckis, E.; Tani, B.S.

    1991-07-01

    A set of experiments, based on the application of the Unsaturated Test method to the reaction of UO 2 with EJ-13 water, has been conducted over a period of 182.5 weeks. One half of the experiments have been terminated, while one half are still ongoing. Solutions that have dripped from UO 2 specimens have been analyzed for all experiments, while the reacted UO 2 surfaces have been examined for only the terminated experiments. A pulse of uranium release from the UO 2 solid, in conjunction with the formation of dehydrated schoepite on the surface of the UO 2 , was observed during the 39- to 96-week period. Thereafter, the uranium release decreased and a second set of secondary phases was observed. The latter phases incorporate cations from the EJ-13 water and include boltwoodite, uranophane, sklodowskite, compreignacite, and schoepite. The experiments are being continued to monitor for additional changes in solution composition and secondary phase formation, and have now reached the 319-week period. 9 refs., 17 figs., 25 tabs

  18. Nanoindentation measurements of the mechanical properties of zirconium matrix and hydrides in unirradiated pre-hydrided nuclear fuel cladding

    International Nuclear Information System (INIS)

    Rico, A.; Martin-Rengel, M.A.; Ruiz-Hervias, J.; Rodriguez, J.; Gomez-Sanchez, F.J.

    2014-01-01

    It is well known that the mechanical properties of the nuclear fuel cladding may be affected by the presence of hydrides. The average mechanical properties of hydrided cladding have been extensively investigated from a macroscopic point of view. In addition, the mechanical and fracture properties of bulk hydride samples fabricated from zirconium plates have also been reported. In this paper, Young’s modulus, hardness and yield stress are measured for each phase, namely zirconium hydrides and matrix, of pre-hydrided nuclear fuel cladding. To this end, nanoindentation tests were performed on ZIRLO samples in as-received state, on a hydride blister and in samples with 150 and 1200 ppm of hydrogen homogeneously distributed along the hoop direction of the cladding. The results show that the measured mechanical properties of the zirconium hydrides and ZIRLO matrix (Young’s modulus, hardness and yield stress) are rather similar. From the experimental data, the hydride volume fraction in the cladding samples with 150 and 1200 ppm was estimated and the average mechanical properties were calculated by means of the rule of mixtures. These values were compared with those obtained from ring compression tests. Good agreement between the results obtained by both methods was found

  19. Routine plasma analysis for 2-[18F]fluorotyrosine by SAX-cartridges

    International Nuclear Information System (INIS)

    Kling, P.; Coenen, H.H.; Stoecklin, G.

    1990-01-01

    There is a great necessity for simple, reliable, and fast methods of plasma analysis. While HPLC is generally the most effective method, it is rather time consuming and expensive in a routine setting with numerous plasma samples. The authors have developed a new method for determination of the amino acid analogue 2-[ 18 F]fluorotyrosine using SAX columns (Adsorbex R SAX, 400 mg, Merck). The results obtained agree within 5% with those determined by reverse phase HPLC

  20. Cover layer technology and a new hard coat for cartridge-free Blu-ray disc

    Science.gov (United States)

    Kang, Tae-Sik; Han, Mi Young; Lee, Seong-Keun; Jang, Sung Hoon; Hong, Young Jun; Seo, Hun; Lee, Chang-Ho

    2004-09-01

    Spin coating method for cover layer of Blu-ray Disc (BD) has been studied and a new hard coat resin including antifouling property has been developed. A vacuum chuck was newly designed to minimize the ski-jump effect. 3 mm hard coat layer was stacked onto the 97 mm cover layer by spin coating method.

  1. Hydrogen production in the K-Basin ion exchange columns, modules and cartridge filters

    International Nuclear Information System (INIS)

    1994-01-01

    K-Basin uses ion exchange modules and ion exchange (IX) columns for removing radionuclides from the basin water. When the columns and modules are loaded, they are removed from service, drained and stored. After a few IX columns accumulate in storage, they are moved to a burial box. One of the burial box contains 33 columns and the other, six. The radionuclides act on the liquid left within and adhering to the beads to produce hydrogen. This report describes the generation rate, accumulation rate and significance of that accumulation. This summary also highlights those major areas of concern to the external (to Westinghouse Hanford Company [WHC]) reviewers. Appendix H presents the comments made by the external reviewers and, on a separate sheet, the responses to those comments. The concerns regarding the details of the analytical approach, are addressed in Appendix H and in the appropriate section

  2. Rapid purification of radiodinated glucagon with Sep-PakR reversed phase cartridges

    International Nuclear Information System (INIS)

    Borghi, V.C.; Nascimento, M.; Wajchenberg, B.L.

    1989-01-01

    A simple, rapid method is described for the purification of radioiodinated glucagon for use in radioimmunoassay. Samples of the radioiodinated hormone, before and after purification are analysed on polyacrylamide gel electrophoresis. The 125 I incorporation in these samples is also checked through thrichloroacetic acid precipitation. The usefulness of this labeled glucagon in radioimmunoassay is demonstrated by its biding to specific antibodies. (M.A.C.) [pt

  3. An On-Chip Nano-Plasmonics Based Urine Protein Assay Cartridge, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — Long-term exposure to microgravity and radiation during space exploration can pose a critical threat to the health of a flight crew. Real-time monitoring of urine...

  4. 77 FR 4362 - Certain Toner Cartridges and Components Thereof; Receipt of Complaint; Solicitation of Comments...

    Science.gov (United States)

    2012-01-27

    .../b/a Image Toner) of GA; E-Max Group, Inc. (d/b/a Databazaar.com ) of FL; Green Project, Inc. of CA; GreenLine Paper Company, Inc. of PA; IJSS Inc. (d/b/a TonerZone.com (d/b/a InkJetSuperstore.com )) of CA... health and welfare in the United States, competitive conditions in the United States economy, the...

  5. An On-Chip Nano-Plasmonics Based Urine Protein Assay Cartridge, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Long-term exposure to microgravity and radiation during space exploration can pose a critical threat to the health of a flight crew. Real-time monitoring of urine...

  6. On-Demand Production of Flow-Reactor Cartridges by 3D Printing of Thermostable Enzymes.

    Science.gov (United States)

    Maier, Manfred; Radtke, Carsten P; Hubbuch, Jürgen; Niemeyer, Christof M; Rabe, Kersten S

    2018-05-04

    The compartmentalization of chemical reactions is an essential principle of life that provides a major source of innovation for the development of novel approaches in biocatalysis. To implement spatially controlled biotransformations, rapid manufacturing methods are needed for the production of biocatalysts that can be applied in flow systems. Whereas three-dimensional (3D) printing techniques offer high-throughput manufacturing capability, they are usually not compatible with the delicate nature of enzymes, which call for physiological processing parameters. We herein demonstrate the utility of thermostable enzymes in the generation of biocatalytic agarose-based inks for a simple temperature-controlled 3D printing process. As examples we utilized an esterase and an alcohol dehydrogenase from thermophilic organisms as well as a decarboxylase that was thermostabilized by directed protein evolution. We used the resulting 3D-printed parts for a continuous, two-step sequential biotransformation in a fluidic setup. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  7. Small-Caliber Ammunition Identification Guide. Volume 1. Small-Arms Cartridges Up to 15 mm

    Science.gov (United States)

    1978-06-01

    ti acer - T trac~aute, traCLur, Traiong, traceri traccusc T[ R ElD. tir r6duitc. Gallery practicc, surhcalibcr TI’traiqan ce pcrforaiute AP-T V. B...Mukden Arsenal in 1929. ý,A A242 A248 SWEDEN MALAYSIA 2 Made at Maricbcrg Ammunition 1973. Factory. 1925-1928, 4 DOMINICAN RLPUBIAC ITALY 60 1960

  8. 76 FR 41822 - In the Matter of Certain Toner Cartridges and Components Thereof; Notice of Commission...

    Science.gov (United States)

    2011-07-15

    ... Imaging Products Inc. of North York, Ontario; Acecom Inc.--San Antonia (d/b/a/ Inksell.com ) of San... Electronics Co., Ltd of Chungchongbuk-do, South Korea; Huizhou Jahwa Electronics Co., Ltd. of Guangdong... health and welfare, (2) competitive conditions in the U.S. economy, (3) U.S. production of articles that...

  9. Investigating the Retention Mechanisms of Liquid Chromatography Using Solid-Phase Extraction Cartridges

    Science.gov (United States)

    O'Donnell, Mary E.; Musial, Beata A.; Bretz, Stacey Lowery; Danielson, Neil D.; Ca, Diep

    2009-01-01

    Liquid chromatography (LC) experiments for the undergraduate analytical laboratory course often illustrate the application of reversed-phase LC to solve a separation problem, but rarely compare LC retention mechanisms. In addition, a high-performance liquid chromatography instrument may be beyond what some small colleges can purchase. Solid-phase…

  10. Specification for the Performance, Design, Development and Test Requirements of a Magnetic Tape Cartridge Replay Machine.

    Science.gov (United States)

    1983-11-23

    fixing screws, bolts , pins, studs , switches, indicators and other protruding components shall be protected from accidental damage by guards or shields...active-low TTL- compatible signals which shall enter the CRM through a multipin conector . Equipment to generate those signals is not described by this

  11. A new method activation analysis of 131I in charcoal cartridge sampler

    International Nuclear Information System (INIS)

    Lai Caifeng; Xu Jiayun; Qin Jianguo; Wang Dalun

    2011-01-01

    Instead of the traditional method for measuring 1311 activation by calibrating the detecting efficiency, MCNP5 calculation and ill-posed equation solution were used in a new method for analysing 131 I activation and depth distribution in sample box. Because of no necessary to prepare for standard sample and calibrate the efficiency, it makes the survey of 131 I more quickly and accurately and is able to take into account the physics processes of 131 I in the sample box. (authors)

  12. 76 FR 66964 - Certain Inkjet Ink Cartridges With Printheads and Components Thereof; Notice of the Commission's...

    Science.gov (United States)

    2011-10-28

    ... complaint named the following entities as respondents: MicroJet Technology Co., Ltd. of Hsinchu City, Taiwan (``MicroJet''); ain Asia Pacific Microsystems, Inc. of Hsinchu City, Taiwan (``APM''); Mipo Technology.... Respondent MicroJet defaulted. Respondent PTC did not participate in the hearing and failed to file post...

  13. 105 K east ion exchange and cartridge filter restart instrumentation acceptance test report

    International Nuclear Information System (INIS)

    Whitehurst, R.

    1996-01-01

    Acceptance Test Report following the completion of ATP-012 for the 105KE CP-A and CP-A Computer and PLC Panels. The test was conducted from 11/13/95 to 12/11/95. Three test discrepancies were generated during the ATP and all were dispositioned and closed. All sections were completed except Section 5.9 which was deleted per ECN 190556

  14. Hydrogen production in the K-Basin ion exchange columns, modules and cartridge filters

    Energy Technology Data Exchange (ETDEWEB)

    1994-12-21

    K-Basin uses ion exchange modules and ion exchange (IX) columns for removing radionuclides from the basin water. When the columns and modules are loaded, they are removed from service, drained and stored. After a few IX columns accumulate in storage, they are moved to a burial box. One of the burial box contains 33 columns and the other, six. The radionuclides act on the liquid left within and adhering to the beads to produce hydrogen. This report describes the generation rate, accumulation rate and significance of that accumulation. This summary also highlights those major areas of concern to the external (to Westinghouse Hanford Company [WHC]) reviewers. Appendix H presents the comments made by the external reviewers and, on a separate sheet, the responses to those comments. The concerns regarding the details of the analytical approach, are addressed in Appendix H and in the appropriate section.

  15. 77 FR 12325 - Certain Toner Cartridges and Components Thereof Corrected Notice of Institution of Investigation

    Science.gov (United States)

    2012-02-29

    ...., Ltd., d/b/a Huebon Co., Limited, d/b/a Ink-Tank, 3/F, No. 1 Industrial Building, Pingdong 2 Road....V., Avenida del Parque 1175, Monterrey Technology Park, Cienega de Flores, Nuevo Leon, Mexico 65550...., 7611 Green Meadows Drive, Lewis Center, OH 43035. Discount Office Items, Inc., 302 Industrial Drive...

  16. Determination of decamethylcyclopentasiloxane in air using commercial solid phase extraction cartridges.

    Science.gov (United States)

    Kierkegaard, Amelie; McLachlan, Michael S

    2010-05-21

    Decamethylcyclopentasiloxane (D(5)), a high production volume chemical used in personal care products, has been designated for regulation in Canada and is under review in the EU because of concerns about its persistence and potential for bioaccumulation in the environment. D(5) is a volatile compound expected to be found primarily in air, but there is little information on atmospheric concentrations due to the lack of sensitive analytical methods. Here a simple and sensitive method to determine D(5) in ambient air is presented. The challenge in the environmental analysis of D(5) is avoiding contamination. Our method is based on the high trapping efficiency of the sorbent Isolute ENV+, combined with a comparably high sampling rate. A small amount of sorbent (10 mg) is eluted in a small volume of n-hexane (0.1-0.6 mL), which is injected onto a GC/MS system without further processing. The simplicity of the method enables the use of a field blank for every sample to trace contamination. The method provides low limits of quantification (approximately 0.3 ng/m(3)), good repeatability and limited breakthrough (approximately 1%). By lowering the limit of quantification compared to published work by almost two orders of magnitude, it became possible to quantify D(5) in ambient air at locations remote from strong point sources. The concentrations at a rural Swedish site ranged from 0.7 to 8 ng/m(3) over a period of 4 months. 2010 Elsevier B.V. All rights reserved.

  17. 78 FR 23955 - Certain Toner Cartridges and Components Thereof; Commission Determination Not To Review an...

    Science.gov (United States)

    2013-04-23

    ... February 27, 2012, based upon a complaint filed on behalf of Canon, Inc. of Tokyo, Japan; Canon U.S.A., Inc... activities involving other types of entry either are adversely affecting it or likely to do so. For... have on (1) the public health and welfare, (2) competitive conditions in the U.S. economy, (3) U.S...

  18. 49 CFR 173.230 - Fuel cell cartridges containing hazardous material.

    Science.gov (United States)

    2010-10-01

    ... integral vent feature) is deemed to pass the fire test if: (A) The internal pressure vents to zero gauge... required to power the equipment, plus two spares; (5) Large robust articles containing fuel cells may be...

  19. Statistical Analysis of Firearms/Toolmarks Interpretation of Cartridge Case Evidence Using IBIS and Bayesian Networks

    Science.gov (United States)

    2015-10-24

    representations of the same surface. 54 At one stage Cambridge Instruments marketed a comparison SEM...versus-test scores (an indication of the reproducibility of marketing within the file. The solid curve represents the best-known non-match (BKNM) curve...34, "FederalAmericanEagle", "Unknown", "Unknown", "FederalAmericanEagle", "Unknown", "Remington") Primer <- c("SSG", " STP ", "SFT", "SFG", " STP ", "SSG

  20. NSRR experiment with un-irradiated uranium-zirconium hydride fuel. Design, fabrication process and inspection data of test fuel rod

    Energy Technology Data Exchange (ETDEWEB)

    Sasajima, Hideo; Fuketa, Toyoshi; Ishijima, Kiyomi; Kuroha, Hiroshi; Ikeda, Yoshikazu [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Aizawa, Keiichi

    1998-08-01

    An experiment plan is progressing in the Nuclear Safety Research Reactor (NSRR) to perform pulse-irradiation with uranium-zirconium hydride (U-ZrH{sub x}) fuel. This fuel is widely used in the training research and isotope production reactor of GA (TRIGA). The objectives of the experiment are to determine the fuel rod failure threshold and to investigate fuel behavior under simulated reactivity initiated accident (RIA) conditions. This report summarizes design, fabrication process and inspection data of the test fuel rods before pulse-irradiation. The experiment with U-ZrH{sub x} fuel will realize precise safety evaluation, and improve the TRIGA reactor performance. The data to be obtained in this program will also contribute development of next-generation TRIGA reactor and its safety evaluation. (author)

  1. The effect of ultraviolet and visible radiation on the readout obtained from γ-irradiated and unirradiated CaSO4:Dy in teflon discs

    International Nuclear Information System (INIS)

    Bartnik, D.L.; Calvert, R.L.; Young, J.G.

    1982-07-01

    The effect of ultraviolet and visible radiation on the readout obtained from the main dosimetry peak of CaSO 4 :Dy in teflon discs is explained by the net result of three separate factors, namely (i) an inherent response, (ii) a phototransfer and (iii) an optical bleaching. Their dependence on wavelength, irradiance and radiant exposure has been studied using a fluorescent light enclosed in a perspex diffuser and a 200W mercury-xenon lamp in conjunction with narrow bandpass filters to isolate specific wavelengths

  2. Longitudinal growth in children with non-Hodgkin's lymphoma and children with acute lymphoblastic leukemia: Comparison between unirradiated and irradiated patients

    International Nuclear Information System (INIS)

    Marky, I.; Samuelsson, B.O.; Mellander, L.; Karlberg, J.

    1991-01-01

    Longitudinal growth was studied in children treated for non-Hodgkin's lymphoma (NHL). The aim of the study was to compare these children's growth velocity with findings in a previous study we performed on age-matched children with acute lymphoblastic leukemia (ALL) who received cranial irradiation. Nine children with NHL with an onset time of treatment between 4 and 9 years of age (mean 6.5 years) were studied with annual body measurements taken from the time of the diagnosis and thereafter annually during the following 4 years. None of the children received cranial irradiation. During the first treatment year a significantly low mean height velocity was observed (-1.4 standard deviation score [SDS]) for the NHL group. The consecutive two 1 year periods showed a normalization of the mean height velocity. For the group of children with ALL, there was a more prominent negative effect on height during the first 2 years of treatment than for the NHL group in the present study. After the cessation of therapy, the children with NHL showed a reduced catch-up growth compared with the children with ALL. The explanation offered is that cranial irradiation has a heavier impact on growth than chemotherapy during the first 2 years of treatment, but an intense chemotherapy during the maintenance period could have a considerable impact in blunting growth

  3. Development of methodology for characterization of cartridge filters from the IEA-R1 using the Monte Carlo method

    International Nuclear Information System (INIS)

    Costa, Priscila

    2014-01-01

    The Cuno filter is part of the water processing circuit of the IEA-R1 reactor and, when saturated, it is replaced and becomes a radioactive waste, which must be managed. In this work, the primary characterization of the Cuno filter of the IEA-R1 nuclear reactor at IPEN was carried out using gamma spectrometry associated with the Monte Carlo method. The gamma spectrometry was performed using a hyperpure germanium detector (HPGe). The germanium crystal represents the detection active volume of the HPGe detector, which has a region called dead layer or inactive layer. It has been reported in the literature a difference between the theoretical and experimental values when obtaining the efficiency curve of these detectors. In this study we used the MCNP-4C code to obtain the detector calibration efficiency for the geometry of the Cuno filter, and the influence of the dead layer and the effect of sum in cascade at the HPGe detector were studied. The correction of the dead layer values were made by varying the thickness and the radius of the germanium crystal. The detector has 75.83 cm 3 of active volume of detection, according to information provided by the manufacturer. Nevertheless, the results showed that the actual value of active volume is less than the one specified, where the dead layer represents 16% of the total volume of the crystal. A Cuno filter analysis by gamma spectrometry has enabled identifying energy peaks. Using these peaks, three radionuclides were identified in the filter: 108m Ag, 110m Ag and 60 Co. From the calibration efficiency obtained by the Monte Carlo method, the value of activity estimated for these radionuclides is in the order of MBq. (author)

  4. 76 FR 28457 - In the Matter of Certain Toner Cartridges and Components Thereof; Determination Not To Review an...

    Science.gov (United States)

    2011-05-17

    ...'l, Ltd. of Zhuhai, China; Ninestar Technology Co., Ltd. of Zhuhai, China; Ninestar Management Co., Ltd. of Zhuhai, China; Zhuhai Seine Technology Co. of Zhuhai, China; Seine Image Int'l Co. of Shatin...; Nano Pacific Corp. of South San Francisco, California; Ninestar Tech. Co., Ltd. of City of Industry...

  5. Design of a micro-cartridge system for the robotic assembly of exchangeable AFM-probe tips

    DEFF Research Database (Denmark)

    Bartenwerfer, Malte; Eichhorn, Volkmar; Fatikow, Sergej

    2013-01-01

    demand an even higher lateral resolution of the measurements. The atomic force microscope (AFM) is a common tool for this characterization and a standard instrument for all kinds of research and development disciplines. However, the characterization of three dimensional high-aspect ratio and sidewall...... structures remains a hardly accomplishable task. Novel exchangeable and customizable scanning probe tips, so-called NanoBits, can be attached to standard AFM cantilevers offering unprecedented freedom in adapting the shape and size of the tips to the surface topology of the specific application. The ultimate...

  6. Study of cartridge rupture detection installations; Contribution a l'etude des installations de detection de ruptures de gaine

    Energy Technology Data Exchange (ETDEWEB)

    Graftieaux, J; Douet, P; Roguin, A [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1967-07-01

    Very numerous physical or technological parameters are involved in the preparation of projects for can rupture detection installations. These parameters are connected essentially with the design of the reactor, the detector used, the disposition of the pneumatic circuits, the type of fuel and the safety required. The present report analyses the main problems arising and their mutual compatibilities; it defines a certain number of ideas which had up till now been accepted implicitly in the design. (authors) [French] De tres nombreux parametres physiques ou technologiques interviennent dans l'etablissement du projet d'une installation de detection de ruptures de gaines. Ces parametres decoulent essentiellement de la conception de la pile, du detecteur utilise, de l'organisation des circuits pneumatiques, du type du combustible et de la securite souhaitee. Le present document analyse les principaux problemes qui se posent ainsi que leurs compatibilites reciproques et precise un certain nombre de notions jusqu'alors admises implicitement lors de l'etablissement des projets. (auteurs)

  7. An innovative bovine odorant binding protein-based filtering cartridge for the removal of triazine herbicides from water.

    Science.gov (United States)

    Bianchi, Federica; Basini, Giuseppina; Grolli, Stefano; Conti, Virna; Bianchi, Francesco; Grasselli, Francesca; Careri, Maria; Ramoni, Roberto

    2013-01-01

    Odorant binding protein (OBP) is a multi-functional scavenger for small hydrophobic molecules dissolved in the mucus lining the nasal epithelia of mammals, characterized by broad ligand binding specificity towards a large number of structurally unrelated natural and synthetic molecules of different chemical classes. Here, we demonstrate for the first time the application of OBP as the active element of an innovative filtering matrix for the removal of environmental pollutants such as triazine herbicides from water samples. The filtering device, obtained by coupling histidine-tagged bovine OBP to a nickel nitrilotriacetic acid (Ni-NTA) agarose resin, was characterized in terms of retention capacity for the herbicides atrazine, simazine, and propazine. Analysis of these herbicides at trace levels with solid-phase microextraction followed by gas chromatography-mass spectrometry using the selected ion monitoring mode proved the capabilities of the proposed device for the decontamination of surface and groundwater samples in the 0.2-2,300 μg/L concentration range, obtaining a reduction in the triazine content greater than 97 %, thus suggesting its possible use for the potabilization of water.

  8. 76 FR 51055 - In the Matter of Certain Inkjet Ink Cartridges with Printheads and Components Thereof; Notice of...

    Science.gov (United States)

    2011-08-17

    ... investigation. The complaint named the following entities as respondents: MicroJet Technology Co., Ltd. of Hsinchu City, Taiwan (``MicroJet''); Asia Pacific Microsystems, Inc. of Hsinchu City, Taiwan (``APM... the investigation. Respondent MicroJet defaulted. Respondent PTC did not participate in the hearing...

  9. 76 FR 60871 - In the Matter of Certain Toner Cartridges and Components Thereof; Notice of Commission Final...

    Science.gov (United States)

    2011-09-30

    ...-Toner''); Alpha Image Tech of South El Monte, California (``Alpha Image''); ACM Technologies, Inc. of Corona, California (``ACM''); Virtual Imaging Products Inc. of North York, Ontario; Acecom Inc.--San... Image, Copy Tech, LTT, C&R, ACM, Ink Master, Direct Billing, Ink Tech, QCI, IJSS, Acecom, Ninestar Tech...

  10. Source apportionment of PM{sub 10} utilising Automatic Cartridge Collection Unit (ACCU) and TEOM systems in Neath Port Talbot

    Energy Technology Data Exchange (ETDEWEB)

    Hooper, M.J.; Hollingsworth, P. [Neath Port Talbot Borough Council, Neath Port Talbot (United Kingdom); Stone, I.M.; Merefield, J.R. [Exeter Univ., Earth Resources Centre, Exeter (United Kingdom)

    1999-10-01

    The background to this study is the review and assessment of air quality as required by Part IV of the Environment Act 1995. A detailed emissions inventory indicated that there might be a significant problem with PM{sub 10} in the Taibach/Margam area of Port Talbot. This was confirmed by continuous monitoring data from the Automatic Urban Network site in the area at Groeswen hospital. These data, when coupled with wind direction data, enabled the production of pollution roses that showed that the highest average PM{sub 10} levels occurred when the wind was blowing towards the residential area from a large significant local source in the west and south-west, i.e. a steel works. The Council is carrying out a stage 3 assessment of PM{sub 10} in this area with a high probability that an Air Quality Management Action Area (AQMA) will need to be declared. It has therefore become clear, that in order to be able to proceed sensibly to an action plan and attempt to meet Air Quality Objectives, identification of the contribution of PM{sub 10} from specific sources would be required. Initial fingerprinting studies were carried out in partnership with Exeter university and, at an early stage, an Air Quality Management Working Group was formed with the works and the Environment Agency to enable constructive dialogue to take place. (Author)

  11. A study of the behaviour of irradiated or unirradiated grafts in the camera aquosa of irradiated and unirradiated animals; Etude du comportement d'un greffon irradie ou non, transplante dans la chambre anterieure de l'oeil d'un animal irradie ou non

    Energy Technology Data Exchange (ETDEWEB)

    Djalali-Behzad, G [Commissariat a l' Energie Atomique, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

    1969-06-01

    Following grafts of new born mice spinal ganglia in the 'camera aquosa' of adult mice, the authors tried hematopoietic tissue grafts in the same conditions. The growth of iso-logous and hetero-logous bone marrow in the 'camera aquosa' showed that this tissue, even after exposure to supralethal doses, was capable of survival and growth. A counter-experiment with non irradiated bone marrow grafts in the 'camera aquosa' of rats delivered 700 rads led to the conclusion that the environment, intoxicated by exposure, acted on the graft so that after vascularization it became unable to grow. (author) [French] Apres avoir greffe des ganglions rachidiens de souriceaux nouveaux-nes dans la chambre anterieure de l'oeil de souris adultes, l'auteur a tente de greffer du tissu hematopoietique de la meme facon. La proliferation de la moelle osseuse isologue et heterologue, dans la chambre anterieure de l'oeil, lui a permis de mettre en evidence une certaine capacite de survie et de proliferation de ce tissu irradie meme a dose supraletale. Par une contre-experimentation, c'est-a-dire par la greffe de moelle non irradiee dans la chambre anterieure de rats irradies a 700 rads, il conclut que le milieu ambiant, intoxique par l'irradiation, agit sur le greffon de telle sorte que ce dernier, apres s'etre vascularise, devient depourvu de son aptitude de proliferation. (auteur)

  12. A study of the behaviour of irradiated or unirradiated grafts in the camera aquosa of irradiated and unirradiated animals; Etude du comportement d'un greffon irradie ou non, transplante dans la chambre anterieure de l'oeil d'un animal irradie ou non

    Energy Technology Data Exchange (ETDEWEB)

    Djalali-Behzad, G. [Commissariat a l' Energie Atomique, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

    1969-06-01

    Following grafts of new born mice spinal ganglia in the 'camera aquosa' of adult mice, the authors tried hematopoietic tissue grafts in the same conditions. The growth of iso-logous and hetero-logous bone marrow in the 'camera aquosa' showed that this tissue, even after exposure to supralethal doses, was capable of survival and growth. A counter-experiment with non irradiated bone marrow grafts in the 'camera aquosa' of rats delivered 700 rads led to the conclusion that the environment, intoxicated by exposure, acted on the graft so that after vascularization it became unable to grow. (author) [French] Apres avoir greffe des ganglions rachidiens de souriceaux nouveaux-nes dans la chambre anterieure de l'oeil de souris adultes, l'auteur a tente de greffer du tissu hematopoietique de la meme facon. La proliferation de la moelle osseuse isologue et heterologue, dans la chambre anterieure de l'oeil, lui a permis de mettre en evidence une certaine capacite de survie et de proliferation de ce tissu irradie meme a dose supraletale. Par une contre-experimentation, c'est-a-dire par la greffe de moelle non irradiee dans la chambre anterieure de rats irradies a 700 rads, il conclut que le milieu ambiant, intoxique par l'irradiation, agit sur le greffon de telle sorte que ce dernier, apres s'etre vascularise, devient depourvu de son aptitude de proliferation. (auteur)

  13. Refueling device for a nuclear reactor with fast neutrons

    International Nuclear Information System (INIS)

    Artemev, L.N.; Vitalevitsch, K.V.

    1978-01-01

    The refueling device has got a drum-shaped cartridge containing cells for unirradiated fuel assemblies and control rods as well as a grab for manipulation. The cells for the fuel assemblies are identical with those for the control rods. For the control rods in stock and those on the way from the drum-shaped magazine to the refueling mechanism there are provided cup-shaped casings (adapters) adapting their ends to the dimensions of the fuel assemblies. The casing is clamped to an annular tee-slot below the top by means of a collet. By this means fuel assemblies as well as control rods can be handled with the grab. By means of a stop on the grab the casing can be detached from the control rod. (DG) [de

  14. Experimental studies on the sterile male technique of spodoptera litura (F. ) by the gamma radiation from /sup 137/Cs, 3. Experiments of the mating competitiveness between moths irradiated as pupae and unirradiated ones in the field cage

    Energy Technology Data Exchange (ETDEWEB)

    Tsukuda, R; Kiyoku, M [Okayama Univ. (Japan). Faculty of Agriculture

    1973-10-01

    Experiments of the mating competitiveness between the substerilized tobacco cutworms and the normal ones were carried out in a field cage (200 x 120 x 180 cm/plot). Pupae of seven days old reared on an artificial medium during the larval stage irradiated with 12 kR of the gamma rays to substerilize. The normal adults were cultured using leaves of cabbages. Cabbages and soybeans were planted in the purpose of egg laying for adult females mated with males in the cage. Substerilized males only or both substerilized males and females were combined with normal males and females. The mating behavior, longevity, egg deposition, percentage of egg hatch and spermatophore in a receptaculum seminis were investigated. When more than ten substerilized and one normal males were exposed to one female, or more than fourteen substerilized and two normal males were combined two normal females, the substerilized males showed high competitiveness with normal males for virgin females. When both five substerilized males and females placed together with one pair of normal male and female in the cage, or each ten substerilized males and females with each two normals, these substerilized males showed full competitiveness. In addition, it was found that offspring obtained from the combination between substerilized males and normal females were sterile.

  15. Chemical Composition and Evaluation of Nicotine, Tobacco Alkaloids, pH and Selected Flavors in e-Cigarette Cartridges and Refill Solutions

    Science.gov (United States)

    Lisko, Joseph G.; Tran, Hang; Stanfill, Stephen B.; Blount, Benjamin C.; Watson, Clifford H.

    2015-01-01

    Introduction Electronic cigarette (e-cigarette) use is increasing dramatically in developed countries, but little is known about these rapidly evolving products. This study analyzed and evaluated the chemical composition including nicotine, tobacco alkaloids, pH and flavors in 36 e-liquids brands from four manufacturers. Methods We determined the concentrations of nicotine, alkaloids, and select flavors and measured pH in solutions used in e-cigarettes. E-cigarette products were chosen based upon favorable consumer approval ratings from online review websites. Quantitative analyses were performed using strict quality assurance/quality control (QC) validated methods previously established by our lab for the measurement of nicotine, alkaloids, pH and flavors. Results Three-quarters of the products contained lower measured nicotine levels than the stated label values (6% - 42% by concentration). The pH for e-liquids ranged from 5.1 – 9.1. Minor tobacco alkaloids were found in all samples containing nicotine, and their relative concentrations varied widely among manufacturers. A number of common flavor compounds were analyzed in all e-liquids. Conclusions Free nicotine levels calculated from the measurement of pH correlated with total nicotine content. The direct correlation between the total nicotine concentration and pH suggests that the alkalinity of nicotine drives the pH of e-cigarette solutions. A higher percentage of nicotine exists in the more absorbable free form as total nicotine concentration increases. A number of products contained tobacco alkaloids at concentrations that exceed U.S. Pharmacopeia limits for impurities in nicotine used in pharmaceutical and food products. PMID:25636907

  16. High-sensitivity quantitation of a biopharmaceutical Nanobody® in plasma by single-cartridge multi-dimensional solid-phase extraction and UPLC-MS/MS

    NARCIS (Netherlands)

    Bronsema, Kees; Bischoff, Rainer; Bouche, Marie-Paule; Mortier, Kjell; van de Merbel, Nico C.

    2015-01-01

    Background: A major challenge in protein quantitation based on enzymatic digestion of complex biological samples and subsequent LC-MS/MS analysis of a signature peptide is dealing with the high complexity of the matrix after digestion, which can reduce sensitivity considerably. For the quantitation

  17. Heat Transfer Analysis of an Optimized, Flexible Holder System for Freeze-Drying in Dual Chamber Cartridges Using Different State-of-the-Art PAT Tools.

    Science.gov (United States)

    Korpus, Christoph; Pikal, Michael; Friess, Wolfgang

    2016-11-01

    The aim of this study was to determine the heat transfer characteristics of an optimized flexible holder device, using Tunable Diode Laser Absorption Spectroscopy, the Pressure Rise Test, and the gravimetric procedure. Two different controlled nucleation methods were tested, and an improved sublimation process, "preheated plate," was developed. Tunable Diode Laser Absorption Spectroscopy identified an initial sublimation burst phase. Accordingly, steady-state equations were adapted for the gravimetric procedure, to account for this initial non-steady-state period. The heat transfer coefficient, K DCC , describing the transfer from the holder to the DCC, was the only heat transfer coefficient showing a clear pressure dependence with values ranging from 3.81E-04 cal/(g·cm 2 ·K) at 40 mTorr to 7.38E-04 cal/(g·cm 2 ·K) at 200 mTorr. The heat transfer coefficient, K tot , reflecting the overall energy transfer via the holder, increased by around 24% from 40 to 200 mTorr. This resulted in a pressure-independent sublimation rate of around 42 ± 1.06 mg/h over the whole pressure range. Hence, this pressure-dependent increase in energy transfer completely compensated the decrease in driving force of sublimation. The "flexible holder" shows a substantially reduced impact of atypical radiation, improved drying homogeneity, and ultimately a better transferability of the freeze-drying cycle for process optimization. Copyright © 2016 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

  18. Engineering Evaluation Tests of 16 Gauge vs 14 Gauge Staples IAW MIL-STD-1660, 40MM Cartridge on Wooden Pallet

    National Research Council Canada - National Science Library

    Dugan, Jeffery L

    2008-01-01

    .... Three test units were tested with a load of 2,290 lbs, 2,295 lbs, and 2,295 lbs. The testing accomplished on the test units was the Stacking, Repetitive Shock, Drop, Incline-Impact, Forklifting, and Disassembly Tests. Test Units #1...

  19. Chemical Composition and Evaluation of Nicotine, Tobacco Alkaloids, pH, and Selected Flavors in E-Cigarette Cartridges and Refill Solutions.

    Science.gov (United States)

    Lisko, Joseph G; Tran, Hang; Stanfill, Stephen B; Blount, Benjamin C; Watson, Clifford H

    2015-10-01

    Electronic cigarette (e-cigarette) use is increasing dramatically in developed countries, but little is known about these rapidly evolving products. This study analyzed and evaluated the chemical composition including nicotine, tobacco alkaloids, pH, and flavors in 36 e-liquids brands from 4 manufacturers. We determined the concentrations of nicotine, alkaloids, and select flavors and measured pH in solutions used in e-cigarettes. E-cigarette products were chosen based upon favorable consumer approval ratings from online review websites. Quantitative analyses were performed using strict quality assurance/quality control validated methods previously established by our lab for the measurement of nicotine, alkaloids, pH, and flavors. Three-quarters of the products contained lower measured nicotine levels than the stated label values (6%-42% by concentration). The pH for e-liquids ranged from 5.1-9.1. Minor tobacco alkaloids were found in all samples containing nicotine, and their relative concentrations varied widely among manufacturers. A number of common flavor compounds were analyzed in all e-liquids. Free nicotine levels calculated from the measurement of pH correlated with total nicotine content. The direct correlation between the total nicotine concentration and pH suggests that the alkalinity of nicotine drives the pH of e-cigarette solutions. A higher percentage of nicotine exists in the more absorbable free form as total nicotine concentration increases. A number of products contained tobacco alkaloids at concentrations that exceed U.S. pharmacopeia limits for impurities in nicotine used in pharmaceutical and food products. © Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco 2015. This work is written by (a) US Government employee(s) and is in the public domain in the US.

  20. Molecularly imprinted polymer cartridges coupled to high performance liquid chromatography (HPLC-UV) for simple and rapid analysis of fenthion in olive oil.

    Science.gov (United States)

    Bakas, Idriss; Ben Oujji, Najwa; Istamboulié, Georges; Piletsky, Sergey; Piletska, Elena; Ait-Addi, Elhabib; Ait-Ichou, Ihya; Noguer, Thierry; Rouillon, Régis

    2014-07-01

    A combination of molecular modelling and a screening of the library of non-imprinted polymers (NIPs) was used to identify acrylamide as a functional monomer with high affinity towards fenthion, organophosphate insecticide, which is frequently used in the treatment of olives. A good correlation was found between the screening tests and modelling of monomer-template interactions performed using a computational approach. Acrylamide-based molecularly imprinted polymer (MIP) and non-imprinted polymer (NIP) were thermally synthesised in dimethyl formamide (porogen) using ethylene glycol dimethacrylate as a cross-linker and 1,1-azo-bis (isobutyronitrile) as an initiator. The chemical and physical properties of the prepared polymers were characterised. The binding of fenthion by the polymers was studied using solvents with different polarities. The developed MIP showed a high selectivity towards fenthion, compared to other organophosphates (dimethoate, methidathion malalthion), and allowed extraction of fenthion from olive oil samples with a recovery rate of about 96%. The extraction of fenthion using MIPs was much more effective than traditional C18 reverse-phase solid phase extraction and allowed to achieve a low detection limit (LOD) (5 µg L(-1)). Copyright © 2014 Elsevier B.V. All rights reserved.

  1. Clinical evaluation of high-risk HPV detection on self-samples using the indicating FTA-elute solid-carrier cartridge

    NARCIS (Netherlands)

    Geraets, D.T.; Baars, R. van; Alonso, I.; Ordi, J.; Torne, A.; Melchers, W.J.G.; Meijer, C.J.W.; Quint, W.G.V.

    2013-01-01

    BACKGROUND: High-risk human papillomavirus (hrHPV) testing in cervical screening is usually performed on physician-taken cervical smears in liquid-based medium. However, solid-state specimen carriers allow easy, non-hazardous storage and transportation and might be suitable for self-collection by

  2. Determination of Chemical Compounds Generated from Second-generation E-cigarettes Using a Sorbent Cartridge Followed by a Two-step Elution Method.

    Science.gov (United States)

    Uchiyama, Shigehisa; Senoo, Yui; Hayashida, Hideki; Inaba, Yohei; Nakagome, Hideki; Kunugita, Naoki

    2016-01-01

    We developed an analytical method for analyzing electronic cigarette (E-cigarette) smoke, and measured the carbonyl compounds and volatile organic compounds generated by 10 brands of second-generation E-cigarettes. A glass filter (Cambridge filter pad) for particulate matter and a solid sorbent tube packed with Carboxen-572 for gaseous compounds were used to collect E-cigarette smoke. These were then analyzed using a two-step elution method with carbon disulfide and methanol, followed by high-performance liquid chromatography (HPLC) and gas chromatography mass spectrometry (GC/MS). Formaldehyde (FA), acetaldehyde (AA), acetone (AC), acrolein (ACR), propanal (PA), acetol (AT), glyoxal (GO), and methyl glyoxal (MGO) were detected by HPLC in some E-cigarettes. Propylene glycol (PG), glycerol (GLY), and some esters were detected by GC/MS. GO and MGO exist mainly as particulate matter. AA, AC, ACR, PA, and AT exist mainly as gaseous compounds. FA exists as both particulate matter and gaseous compounds. These carbonyl compounds have carbon numbers C1 - C3. The main components of E-liquid are PG (C3) and GLY (C3). Therefore, the oxidation of liquids, such as PG and GLY in E-cigarettes upon incidental contact with the heating element in E-cigarette, is suggested as being a possible cause for carbonyl generation. When the puff number exceeds a critical point, carbonyl generation rapidly increases and then remains constant. The results of this study are now being used to determine the following E-cigarette smoking protocol: puff volume, 55 mL; puff duration, 2 s; and puff number, 30. E-cigarette analysis revealed very large variation in carbonyl concentration among not only different brands, but also different samples of the same product. Typical distributions of carbonyl concentration were not observed in any of the E-cigarettes tested, and the mean values greatly differed from median values.

  3. Exploitation of FTA cartridges for the sampling, long-term storage, and DNA-based analyses of plant-parasitic nematodes.

    Science.gov (United States)

    Marek, Martin; Zouhar, Miloslav; Douda, Ondřej; Maňasová, Marie; Ryšánek, Pavel

    2014-03-01

    The use of DNA-based analyses in molecular plant nematology research has dramatically increased over recent decades. Therefore, the development and adaptation of simple, robust, and cost-effective DNA purification procedures are required to address these contemporary challenges. The solid-phase-based approach developed by Flinders Technology Associates (FTA) has been shown to be a powerful technology for the preparation of DNA from different biological materials, including blood, saliva, plant tissues, and various human and plant microbial pathogens. In this work, we demonstrate, for the first time, that this FTA-based technology is a valuable, low-cost, and time-saving approach for the sampling, long-term archiving, and molecular analysis of plant-parasitic nematodes. Despite the complex structure and anatomical organization of the multicellular bodies of nematodes, we report the successful and reliable DNA-based analysis of nematode high-copy and low-copy genes using the FTA technology. This was achieved by applying nematodes to the FTA cards either in the form of a suspension of individuals, as intact or pestle-crushed nematodes, or by the direct mechanical printing of nematode-infested plant tissues. We further demonstrate that the FTA method is also suitable for the so-called "one-nematode-assay", in which the target DNA is typically analyzed from a single individual nematode. More surprisingly, a time-course experiment showed that nematode DNA can be detected specifically in the FTA-captured samples many years after initial sampling occurs. Collectively, our data clearly demonstrate the applicability and the robustness of this FTA-based approach for molecular research and diagnostics concerning phytonematodes; this research includes economically important species such as the stem nematode (Ditylenchus dipsaci), the sugar beet nematode (Heterodera schachtii), and the Northern root-knot nematode (Meloidogyne hapla).

  4. Partial combustion of a fuel cartridge in reactor G1; Combustion partielle d'une cartouche de combustible dans le reacteur G 1

    Energy Technology Data Exchange (ETDEWEB)

    De, Rouville; Leduc,; Segot, [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    On the 26 october 1956, after having stopped a few days, the G1 reactor was started up again. The burst slug system gave a first warning at 19 h 07 on loading side, a second one at 19 h 13 on unloading side, and so on others. Ath 15 the Control Engineer ordered a quick decrease of power and then, made it rise again from 2 to 5 MW, to find out, with accuracy, the failing channel. Soon after, in order to avoid any exterior contamination, scanning had to be stopped and a {gamma} ray detecting system outside the burst slug piping system, found out the damaged element in the channel 19-13. The health stations recording showed that the highest experienced measures were still notably lower than the maxima permissible levels. The methodical examination and the unloading of the damaged channel lasted three weeks. On the loading side, bare uranium billets could be seen on a magnesia powder bed. On the unloading side, the can was undamaged, but the element's end was hanging inside the gap of the inlet air. Pushed back, about 30 cm (12 in.), on the loading side, the element got blocked up. After several tests, while argon was still being injected, working staff being kept under strict protection conditions, a countersink tube was operating like the one used for drilling. The channel was cleaned up by sucking up, without, however, avoiding slight contamination in the building of the reactor. On the 7 december 1956, the reactor had a divergence at 2 MW, the first since the fault. A hundred or so channels were still giving a background, therefore making the burst slug system inefficient for those channels. Systematical brushing and sucking up were not able to reduce it beyond a certain level. It forced the reactor to operate during several months with 56 unloaded semi-channels. At last, in june 1957, two handling allowed the reactor to operate in a satisfactory way: removal of 1 mm-thickness of graphite, by re-reaming 54 semi-channels and setting on the burst slug detection-devices, some null regulating tension systems, annealing the background due to continuous pollution. This event has been fruitful. A grid trap has been set right ahead the reactor. Stricter instructions have been given for rising power operations and automatic burst slug sy (already improved as said above) has been duplicated by a human control. At last, the fault has pointed out that the reactors with gap had the disadvantage of facilitating the contamination of channels from one to another. On the other hand, graphite stores the radioactive dusts and hinders an easy decontamination. (author) [French] Le 26 octobre 1956, le reacteur G1 etait remis en marche apres un arret de quelques jours. L'installation de detection de rupture de gaines donna un premier signal de prealerte a 19h07 cote chargement, un second a 19h13 cote dechargement, puis d'autres. Le chef de quart ordonna a 19h15 une baisse rapide de la puissance mais voulant reperer le canal fautif avec precision la fit remonter ensuite a 2 puis a 5 MW. Bientot, par crainte de contamination exterieure, on dut arreter l'exploration et c'est par detection {gamma} a l'exterieur des tuyaux de detection de rupture de gaine qu'on identifia la cartouche endommagee dans le canal 19-13. Les enregistrements des stations de sante montrerent que les pointes observees etaient restees notablement inferieures aux limites maxima admissibles. L'examen methodique et le degagement du canal accidente occuperent trois semaines. On put apercevoir cote chargement les billettes d'uranium nues sur un lit de poudre de magnesie; cote dechargement, la gaine etait intacte mais l'extremite de la cartouche 'pendait' a l'interieur de la fente d'arrivee d'air. Repoussee cote chargement d'environ 30 cm, la cartouche se bloqua. Apres des essais divers, toujours sous injection d'argon, et avec des protections severes du personnel, on mit en oeuvre un tube fraise, analogue a ceux utilises pour les forages. On nettoya le canal par aspiration, sans toutefois eviter de legeres contaminations du hall de la pile. Le 7 decembre 1956 eut lieu une premiere divergence a 2 MW. Une centaine de canaux donnaient encore un bruit de fond rendant inoperante pour ces canaux la detection de ruptures de gaines. Des brossages et aspirations systematiques ne purent le reduire ala d'un palier qui obligea a faire fonctionner le reacteur pendant plusieurs mois avec 56 demi-canaux decharges. Enfin, en juin 1957, deux operations rendirent au reacteur un regime pleinement satisfaisant; enlevement d'une epaisseur de 1 mm de graphite par realesage de 54 demi-canaux et montage sur les appareils de detection de dispositifs d'opposition de tension reglable eliminant dans les mesures la part du bruit de fond due a la pollution permanente. Cet incident a ete riche d'enseignements: une grille piege a ete mise en place juste en amont de la pile; les consignes de montee en puissance ont ete rendues plus prudentes, le controle automatique des detections de ruptures de gaines (deja ameliorees comme il a ete dit) a ete double d'un controle humain. Enfin, l'incident a mis en evidence que les piles a fente avaient le defaut de faciliter la contamination des canaux de proche en proche. Par ailleurs le graphite emmagasine les poussieres radioactives et rend la decontamination difficile. (auteur)

  5. Two-gun suicide by simultaneous shots to the head: interdisciplinary reconstruction on the basis of scene investigation, autopsy findings, GSR analysis and examination of firearms, bullets and cartridge cases.

    Science.gov (United States)

    Grosse Perdekamp, Markus; Nadjem, Hadi; Merkel, Joachim; Braunwarth, Roland; Pollak, Stefan; Thierauf, Annette

    2011-07-01

    Suicidal shots fired simultaneously to the head from two handguns are rare. The authors report about a recent case in which a Smith & Wesson cal. 9 mm pistol and a Smith & Wesson cal. .357 Magnum revolver were used. Sitting on a sofa, a 33-year-old man (member of a shooting club) fired two simultaneous shots to the head; the pistol held in the left hand was discharged into the left temple, and the revolver held in the right hand was fired into the mouth. Both weapons remained in the respective hands. An upside-down muzzle imprint in the left temporal region and recoil injuries of a mandibular incisor, and the lower lip indicated that both the pistol and the revolver had been held in an inverted manner at the time of discharge. Blood stains (backspatter) and gunshot residues were present on both firing hands, whereas forward spatter originating from the exit wounds was deposited on the wall behind the suicide's head.

  6. Development of methodology for characterization of cartridge filters from the IEA-R1 using the Monte Carlo method; Desenvolvimento de uma metodologia para caracterizacao do filtro cuno do reator IEA-R1 utilizando o Metodo Monte Carlo

    Energy Technology Data Exchange (ETDEWEB)

    Costa, Priscila

    2014-07-01

    The Cuno filter is part of the water processing circuit of the IEA-R1 reactor and, when saturated, it is replaced and becomes a radioactive waste, which must be managed. In this work, the primary characterization of the Cuno filter of the IEA-R1 nuclear reactor at IPEN was carried out using gamma spectrometry associated with the Monte Carlo method. The gamma spectrometry was performed using a hyperpure germanium detector (HPGe). The germanium crystal represents the detection active volume of the HPGe detector, which has a region called dead layer or inactive layer. It has been reported in the literature a difference between the theoretical and experimental values when obtaining the efficiency curve of these detectors. In this study we used the MCNP-4C code to obtain the detector calibration efficiency for the geometry of the Cuno filter, and the influence of the dead layer and the effect of sum in cascade at the HPGe detector were studied. The correction of the dead layer values were made by varying the thickness and the radius of the germanium crystal. The detector has 75.83 cm{sup 3} of active volume of detection, according to information provided by the manufacturer. Nevertheless, the results showed that the actual value of active volume is less than the one specified, where the dead layer represents 16% of the total volume of the crystal. A Cuno filter analysis by gamma spectrometry has enabled identifying energy peaks. Using these peaks, three radionuclides were identified in the filter: {sup 108m}Ag, {sup 110m}Ag and {sup 60}Co. From the calibration efficiency obtained by the Monte Carlo method, the value of activity estimated for these radionuclides is in the order of MBq. (author)

  7. 76 FR 70422 - Procurement List Additions

    Science.gov (United States)

    2011-11-14

    ..., Disinfectant Cleaner-Degreaser Cartridge Concentrate. NSN: 7930-00-NIB-0593--Refills, Multi-Purpose Cleaner, Cartridge Concentrate. NSN: 7930-00-NIB-0594--Starter Kit, Multi-Purpose Cleaner, Cartridge Concentrate. NPA..., Anniston, AL Service Type/Locations: Rubbish Removal and Recycling Service Department of the Treasury...

  8. Growth Rate and Morphology of a Single Calcium Carbonate Crystal on Polysulfone Film Measured with Time Lapse Raman Micro Spectroscopy

    NARCIS (Netherlands)

    Liszka, B.; Lenferink, Aufrid T.M.; Otto, Cornelis

    2016-01-01

    The growth of single, self- nucleated calcium carbonate crystals on a polysulfone (PSU) film was investigated with high resolution, time lapse Raman imaging. The Raman images were acquired on the interface of the polymer with the crystal. The growth of crystals could thus be followed in time. PSU is

  9. Detection of irradiated peppers by viscosity measurement at extremely high pH

    International Nuclear Information System (INIS)

    Hayashi, Toru; Todoriki, Setsuko

    1996-01-01

    The viscosities of aqueous suspensions of irradiated peppers determined after heat gelatinization were influenced by the pH of the suspension to a greater degree than those of unirradiated ones. Viscosity measurement under an extremely alkaline condition (pH 13.8) resulted in a significant different between irradiated peppers and unirradiated ones, irrespective of the planting locality and storage period. All of the pepper samples irradiated at 5 kGy showed viscosity values significantly lower than unirradiated ones. (Author)

  10. A study of the healthy standard for radiation controlling insect of almond

    International Nuclear Information System (INIS)

    Wang Ying; Wang Weiguo; Li Fengmei

    1992-01-01

    The result of healthy standard research for disinfestation insects of almond by γ-ray irradiation is described. The mortality of insects is more effective by using 1.0 kGy dose. The comparison of good product rate between irradiated and un-irradiated has been studied. Result indicates that good product rate of irradiated sample is 20% higher than unirradiated. In addition, there are no significant difference between irradiated and unirradiated samples on nutrition and chemical parameters

  11. Electron spin resonance (ESR) studies on irradiated cocoa beans and niger seeds

    International Nuclear Information System (INIS)

    Mangaonkar, S.R.; Natarajan, V.; Sastry, M.D.; Desai, S.R.P.; Kulkarni, P.R.

    1997-01-01

    Electron spin resonance (ESR) spectra of irradiated (10kGy) and unirradiated cocoa beans and niger seeds have been compared. Unirradiated cocoa beans failed to give any ESR signal, whereas after irradiation (10kGy) an ESR signal at g = 2.0042 was observed. However, ESR signals are given by both irradiated and unirradiated niger seeds. The intensity of signal was found to be dose-dependent up to 10kGy for both seeds. The signals were stable up to 180 days in both cases. The results indicate the possibility of using ESR for distinguishing between irradiated and unirradiated cocoa beans but not for niger seeds

  12. Bottom loaded filter for radioactive liquid

    International Nuclear Information System (INIS)

    Wendland, W.G.

    1980-01-01

    A specification is given for a bottom loaded filter assembly for filtering radioactive liquids through a replaceable cartridge filter, which includes a lead-filled jacket enveloping a housing having a chamber therein for the filter cartridge. A track arrangement carries a hatch for sealing the chamber. A spacer plug supports the cartridge within guide means associated with the inlet conduit in the chamber. The plug and cartridge drop out of the chamber when the hatch is unbolted and moved laterally of the chamber along the track. During cartridge replacement a new plug and cartridge are supported in the guide means by a spacer bar inserted across the track means under the chamber. The hatch is then slid under the chamber and bolted to a flange on the housing, engaging an O-ring to seal the chamber. (author)

  13. Bottom loaded filter for radioactive liquids

    International Nuclear Information System (INIS)

    Wendland, W.G.

    1980-01-01

    A bottom loaded filter assembly for filtering radioactive liquids through a replaceable cartridge filter is disclosed. The filter assembly includes a lead-filled jacket enveloping a housing having a chamber therein for the filter cartridge. A track arrangement carries a hatch for sealing the chamber. A spacer plug supports the cartridge within guide means associated with the inlet conduit in the chamber. The plug and cartridge drop out of the chamber when the hatch is unbolted and move laterally of the chamber. During cartridge replacement, a new plug and cartridge are supported in the guide means by a spacer bar inserted across the track means under the chamber. The hatch is then slid under the chamber and bolted to the vessel, engaging an o-ring to seal the chamber

  14. Specific effects of small doses of 60Co-γ-radiation applied to the seeds before sowing on the yield of silo maize (small and large plot field experiments)

    International Nuclear Information System (INIS)

    Degner, W.; Schacht, W.; Koepp, R.

    1975-01-01

    Dry seeds of silo maize were cultivated under outside conditions after fractionated irradiation with low radiation doses. The yields of irradiated and unirradiated seeds were compared. The resistance of irradiated and unirradiated plants and ensilage were also studied and compared. The findings are discussed. (GSE/AK) [de

  15. Effect of combinations of gamma irradiation, hot water, Sodium chloride, and Acetic acid treatments on potato-dry rot

    International Nuclear Information System (INIS)

    El-Zayat, M.M.; Farahat, A.A.; Saad, N.H.; Shaarawy, N.S.M.

    1992-01-01

    Gamma irradiation increased the severity of dry rot in potato tubers when they were inoculated with any of 4 species of Fusarium, previously isolated either from irradiated or unirradiated tubers. Treating either irradiated or unirradiated tubers with warm water or sodium chloride solutions following inoculation with F. roseum also increased the severity of dry rot to some extent

  16. Advantageous use of SSA technique to observe effects of thickness, antioxidant and oxygen in gamma irradiated low density polyethylene

    Energy Technology Data Exchange (ETDEWEB)

    Perez, C.J., E-mail: cjperez@fi.mdp.edu.ar [Research Institute of Material Science and Technology (INTEMA), National Research Council (CONICET), Engineering Faculty, Mar del Plata University, Av. J.B. Justo 4302, 7600 Mar del Plata (Argentina); Failla, M.D. [Planta Piloto de Ingenieria Quimica-PLAPIQUI (UNS-CONICET), Camino ' La Carrindanga' Km 7, 8000 Bahia Blanca (Argentina); Carella, J.M. [Research Institute of Material Science and Technology (INTEMA), National Research Council (CONICET), Engineering Faculty, Mar del Plata University, Av. J.B. Justo 4302, 7600 Mar del Plata (Argentina)

    2012-06-20

    Highlights: Black-Right-Pointing-Pointer Information from successive self-nucleation and annealing technique is analyzed. Black-Right-Pointing-Pointer Oxygen and antioxidants reduce crosslinking efficiency by reaction with free radicals. Black-Right-Pointing-Pointer Recognizable differences are obtained in samples irradiated at different atmospheres. - Abstract: Information obtained from successive self-nucleation and annealing (SSA) technique is analyzed, paying special attention to the observable effects of samples thickness and antioxidant and oxygen concentrations. Molecular structure changes for low density polyethylene (LDPE) samples, irradiated under three different atmospheres for doses between 33 and 222 kGy were analyzed, with emphasis on the changes of longer polymethylene crystallizable lengths. Antioxidant and oxygen concentrations were varied for samples of different thickness to study the effects on degradation. The changes in the molecular structure were followed simultaneously by SSA and Infrared spectroscopy (FTIR) via carbonyl group concentration. Preliminary quantifications of the SSA technique sensitivity are also advanced.

  17. Domestic Preparedness Program: Sarin Vapor Challenge and Corn Oil Protection Factor (PF) Testing of Commercial Air-Purifying Negative Pressure Respirators

    National Research Council Canada - National Science Library

    Campbell, Lee

    2003-01-01

    ...) corn-oil protection factor determinations of NPR systems using human subjects. Results indicate that cartridges provide adequate resistance to GB breakthrough against high-concentration challenges...

  18. Adjustments Recommended in Fiscal Year 1982 Ammunition Procurement and Modernization Programs

    Science.gov (United States)

    1981-06-30

    No comment 4.8 No comment Cartridge, 7.6 2-mm., all types Cartridge, .45 caliber ball 31.9 58.3 -0.8 2.9 Cartridge, 1.6 30-mm., TP...4.5 - 1.6 57.5 Inventory exceeds re- quirements for rifle grenade cartridge 2.8 No comment 77.1 No comment - Inventory exceeds re...quirements 10.7 Inventory exceeds re- quirements Premature buy Premature buy 4.5 No comment 38 APPENDIX I APPENDIX

  19. Study of interfacial phenomena of organo-chlorinated steam adsorption on a microporous adsorbent. Case of tri chloro-1,1,1 ethane on activated charcoal

    International Nuclear Information System (INIS)

    Escallon, S.

    1991-06-01

    This study involves the construction and the perfecting of a test system for evaluating the service life of organic vapor cartridges versus 1,1,1 -trichloroethane. Thermogravimetric measurements were carried on in order to suggest a field method to reactive these cartridges, using hot air flow system. Assessment of adsorption rate during experiment is measured with a new electrical method. (author)

  20. A Modern Apparatus for Performing Flash Chromatography: An Experiment for the Organic Laboratory

    Science.gov (United States)

    Naumiec, Gregory R.; Del Padre, Angela N.; Hooper, Matthew M.; Germaine, Alison St.; DeBoef, Brenton

    2013-01-01

    A modern apparatus for performing flash chromatography using commercially available, prepacked silica cartridges has been developed. The key advantage of this system, when compared to traditional flash chromatography, is its use of commercially available silica cartridges, which obviates the need for students to handle silica gel. The apparatus…

  1. 49 CFR 176.84 - Other requirements for stowage and segregation for cargo vessels and passenger vessels.

    Science.gov (United States)

    2010-10-01

    ... persons on passenger vessels. 94 Plastic jerricans and plastic drums not permitted under deck. 95 Stow... Stowage category “04” for projectiles or cartridges for guns, cannons or mortars; Stowage category “08... projectiles or cartridges for guns, cannons or mortars; Stowage category “07” for other types; magazines must...

  2. 76 FR 57719 - Procurement List; Proposed Additions

    Science.gov (United States)

    2011-09-16

    ... proposed for addition to the Procurement List for production by the nonprofit agencies listed: Products NSN: 7930-00-NIB-0583--Refills, Bathroom Cleaner and Deodorizer, Cartridge Concentrate. NSN: 7930-00-NIB-0584--Starter Kit, Bathroom Cleaner and Deodorizer, Cartridge Concentrate. NSN: 7930-00-NIB-0585...

  3. 40 CFR 63.11511 - What definitions apply to this subpart?

    Science.gov (United States)

    2010-07-01

    ... detonation gun spraying. Water curtain means a type of control device that draws the exhaust stream through a... emissions points and then convey the captured gas stream to a control device, as part of a complete control..., plenums, and fans. Cartridge filter means a type of control device that uses perforated metal cartridges...

  4. 76 FR 57913 - Amendments to National Emission Standards for Hazardous Air Pollutants for Area Sources: Plating...

    Science.gov (United States)

    2011-09-19

    ... Fixture Fitting and Trim Manufacturing; Other Metal Valve and Pipe Fitting Manufacturing; 332999, All... thermal spraying operation and exhaust them to a water curtain, or a cartridge, fabric, or HEPA filter... from the thermal spraying operation and exhaust them to a cartridge, fabric, or HEPA filter...

  5. 76 FR 35744 - Amendments to National Emission Standards for Hazardous Air Pollutants for Area Sources: Plating...

    Science.gov (United States)

    2011-06-20

    ... Metal Valve and Pipe Fitting Manufacturing; 332999, All Other Miscellaneous Fabricated Metal Product... spraying operation and exhaust them to a water curtain, or a cartridge, fabric, or HEPA filter... from the thermal spraying operation and exhaust them to a cartridge, fabric, or HEPA filter...

  6. Development of procedures for calculating stiffness and damping properties of elastomers in engineering applications. Part 4: Testing of elastomers under a rotating load. [resonance testing

    Science.gov (United States)

    Darlow, M. S.; Smalley, A. J.

    1977-01-01

    A test rig designed to measure stiffness and damping of elastomer cartridges under a rotating load excitation is described. The test rig employs rotating unbalance in a rotor which runs to 60,000 RPM as the excitation mechanism. A variable resonant mass is supported on elastomer elements and the dynamic characteristics are determined from measurements of input and output acceleration. Five different cartridges are considered: three of these are buttons cartridges having buttons located in pairs, with 120 between each pair. Two of the cartridges consist of 360 elastomer rings with rectangular cross-sections. Dynamic stiffness and damping are measured for each cartridge and compared with predictions at different frequencies and different strains.

  7. Multi-chamber nucleic acid amplification and detection device

    Science.gov (United States)

    Dugan, Lawrence

    2017-10-25

    A nucleic acid amplification and detection device includes an amplification cartridge with a plurality of reaction chambers for containing an amplification reagent and a visual detection reagent, and a plurality of optically transparent view ports for viewing inside the reaction chambers. The cartridge also includes a sample receiving port which is adapted to receive a fluid sample and fluidically connected to distribute the fluid sample to the reaction chamber, and in one embodiment, a plunger is carried by the cartridge for occluding fluidic communication to the reaction chambers. The device also includes a heating apparatus having a heating element which is activated by controller to generate heat when a trigger event is detected. The heating apparatus includes a cartridge-mounting section which positioned a cartridge in thermal communication with the heating element so that visual changes to the contents of the reaction chambers are viewable through the view ports.

  8. Oxidation kinetic changes of UO2 by additive addition and irradiation

    International Nuclear Information System (INIS)

    You, Gil-Sung; Kim, Keon-Sik; Min, Duck-Kee; Ro, Seung-Gy

    2000-01-01

    The kinetic changes of air-oxidation of UO 2 by additive addition and irradiation were investigated. Several kinds of specimens, such as unirradiated-UO 2 , simulated-UO 2 for spent PWR fuel (SIMFUEL), unirradiated-Gd-doped UO 2 , irradiated-UO 2 and -Gd-doped UO 2 , were used for these experiments. The oxidation results represented that the kinetic patterns among those samples are remarkably different. It was also revealed that the oxidation kinetics of irradiated-UO 2 seems to be more similar to that of unirradiated-Gd-doped UO 2 than that of SIMFUEL

  9. Incidence of missed inferior alveolar nerve blocks in vital asymptomatic subjects and in patients with symptomatic irreversible pulpitis.

    Science.gov (United States)

    Fowler, Sara; Reader, Al; Beck, Mike

    2015-05-01

    The purpose of this retrospective study was to determine the incidence of missed inferior alveolar nerve (IAN) blocks by using a 1- or 2-cartridge volume of 2% lidocaine with 1:100,000 epinephrine in vital asymptomatic teeth and in emergency patients with symptomatic irreversible pulpitis. As part of 37 studies, 3169 subjects/patients were evaluated for missed IAN blocks. The study included 2450 asymptomatic subjects and 719 emergency patients presenting with symptomatic irreversible pulpitis. Each subject or patient received either a 1- or 2-cartridge volume of 2% lidocaine with 1:100,000 epinephrine. A missed block was defined as no lip numbness at 15-20 minutes after the IAN block. The effect of anesthetic volume on the incidence of missed blocks was assessed by using mixed models logistic regression with individual studies as a random effect. The incidence of missed blocks for asymptomatic subjects was 6.3% for the 1-cartridge volume and 3.8% for the 2-cartridge volume. For patients presenting with irreversible pulpitis, the incidence of missed blocks was 7.7% for the 1-cartridge volume and 2.3% for the 2-cartridge volume. In both asymptomatic subjects and patients with irreversible pulpitis, the 2-cartridge volume was significantly (P = .0395) better than the 1-cartridge volume. There were no significant effects for pulpal diagnosis (P = .7523) or the pulpal diagnosis and anesthetic volume interaction (P = .3973). Concerning missed IAN blocks, we concluded that administration of a 2-cartridge volume was significantly better (P = .0395) than a 1-cartridge volume in both asymptomatic subjects and emergency patients presenting with irreversible pulpitis. Copyright © 2015 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  10. New facilities of the ECN hot cell laboratory

    International Nuclear Information System (INIS)

    Duijves, K.A.; Konings, R.J.M.

    1996-04-01

    A description is given of two recent expansions of the ECN Hot Cell Laboratory in Petten; a production facility for molybdenum-99 and an actinide laboratory, a special facility to investigate unirradiated alpha- and beta-active samples. (orig.)

  11. Influence of gamma radiation on the colour strength and fastness properties of fabric using turmeric (Curcuma longa L.) as natural dye

    International Nuclear Information System (INIS)

    Bhatti, Ijaz A.; Adeel, Shahid; Jamal, M. Asghar; Safdar, Muhammad; Abbas, Muhammad

    2010-01-01

    The effect of gamma radiation on the dyeing of cotton with extract of turmeric (Curcuma longa L.) powder has been investigated. Cotton fabric and turmeric powder were irradiated to absorbed doses of 1, 2, 3, 4 and 6 kGy using Co-60 gamma irradiator. Dyeing parameters such as temperature, pH and mordant concentration were optimized. Dyeing was performed using un-irradiated and irradiated cotton with the extracts of un-irradiated and irradiated turmeric powder in order to investigate the effect of radiation treatment on the colour strength of dyed fabric. The reported data of un-irradiated and irradiated fabrics dyed with un-irradiated and irradiated dyes were obtained using the spectraflash SF-650. The colourfastness to light, rubbing- and washing-fastness properties showed that gamma irradiation has improved the dyeing characteristics from fair to good.

  12. Influence of gamma radiation on the colour strength and fastness properties of fabric using turmeric (Curcuma longa L .) as natural dye

    Science.gov (United States)

    Bhatti, Ijaz A.; Adeel, Shahid; Jamal, M. Asghar; Safdar, Muhammad; Abbas, Muhammad

    2010-05-01

    The effect of gamma radiation on the dyeing of cotton with extract of turmeric ( Curcuma longa L.) powder has been investigated. Cotton fabric and turmeric powder were irradiated to absorbed doses of 1, 2, 3, 4 and 6 kGy using Co-60 gamma irradiator. Dyeing parameters such as temperature, pH and mordant concentration were optimized. Dyeing was performed using un-irradiated and irradiated cotton with the extracts of un-irradiated and irradiated turmeric powder in order to investigate the effect of radiation treatment on the colour strength of dyed fabric. The reported data of un-irradiated and irradiated fabrics dyed with un-irradiated and irradiated dyes were obtained using the spectraflash SF-650. The colourfastness to light, rubbing- and washing-fastness properties showed that gamma irradiation has improved the dyeing characteristics from fair to good.

  13. Influence of gamma radiation on the colour strength and fastness properties of fabric using turmeric (Curcuma longa L.) as natural dye

    Energy Technology Data Exchange (ETDEWEB)

    Bhatti, Ijaz A., E-mail: ijazchem@yahoo.co [Department of Chemistry, University of Agriculture, Faisalabad 38040 (Pakistan); Adeel, Shahid [Department of Chemistry, University of Agriculture, Faisalabad 38040 (Pakistan); Jamal, M. Asghar [Department of Chemistry, G.C. University, Faisalabad 38040 (Pakistan); Safdar, Muhammad [Department of Chemistry, University of A J and K, Muzaffarabad, Azad Kashmir (Pakistan); Abbas, Muhammad [Haris Dyes and Chemicals, Faisalabad 38040 (Pakistan)

    2010-05-15

    The effect of gamma radiation on the dyeing of cotton with extract of turmeric (Curcuma longa L.) powder has been investigated. Cotton fabric and turmeric powder were irradiated to absorbed doses of 1, 2, 3, 4 and 6 kGy using Co-60 gamma irradiator. Dyeing parameters such as temperature, pH and mordant concentration were optimized. Dyeing was performed using un-irradiated and irradiated cotton with the extracts of un-irradiated and irradiated turmeric powder in order to investigate the effect of radiation treatment on the colour strength of dyed fabric. The reported data of un-irradiated and irradiated fabrics dyed with un-irradiated and irradiated dyes were obtained using the spectraflash SF-650. The colourfastness to light, rubbing- and washing-fastness properties showed that gamma irradiation has improved the dyeing characteristics from fair to good.

  14. Decay of paramagnetic centers in polyacetylene

    International Nuclear Information System (INIS)

    Hola, O.

    1994-01-01

    The time dependences of the relative concentration of spins in irradiated and unirradiated samples of polyacetylene have been studied. Similar courses of the decay of paramagnetic centers were observed in both types of samples. (author) 6 refs.; 1 fig

  15. Effects of irradiation on the fracture behavior of austenitic stainless steels

    International Nuclear Information System (INIS)

    Grossbeck, M.L.; Stiegler, J.O.; Holmes, J.J.

    1977-01-01

    Fracture in irradiated materials occurs by mechanisms which occur in unirradiated materials in addition to mechanisms related to irradiation phenomena. The paper examines radiation effects in austenitic stainless steels for use as core structural materials in fast breeder reactors

  16. Expression profiling of murine lung 70 days following exposure to fractionated or acute dose of 1.0 Gy 56Fe- particle irradiation

    Data.gov (United States)

    National Aeronautics and Space Administration — Irradiation of the K-rasLA1 mouse model with a fractionated dose of 1.0Gy 56Fe- particles increases the incidence of invasive carcinoma compared to unirradiated...

  17. Effect of inherited sterility and bacillus thuringiensis on mortality and reproduction of phthorimaea opercullela zeller (lepidoptera: gelechidae)

    International Nuclear Information System (INIS)

    Makee, H.; Tlas, M. D.; Amer, S.; Abdulla, J.

    2008-01-01

    The effect of a commercial formulation of Bacillus thuringiensis (Dipel 2X) upon F 1 progeny of irradiated and unirradiated phthorimaea operculella male parents was investigated. F 1 progeny of irradiated parents was more susceptible to B. thuringiensis than that of unirradiated parents. A combination of irradiation and B. thuringiensis led to higher mortality in F 1 progeny of P. operculella. The LC 50 was 0.406 g/100ml for F 1 progeny of unirradiated parents, but 0.199 g/100ml for those of irradiated parents. There was a great reduction in the pupal weight, fecundity and egg hatchability of F 1 progeny of irradiated patents compared to those unirradiated parents. Such reduction was increased by applying higher concentration of B. thuringiensis. A combination between inherited sterility technique and B. thuringiensis application could give a good controlling result against P. operculella. (author)

  18. Effect of X-rays and u.v.-light on the levels of NAD(P), NAD(P)H and hydroxyproline in Pinus silvestris pollen

    International Nuclear Information System (INIS)

    Zelles, L.

    1978-01-01

    Pollen grains of Pinus Silvestris were irradiated with stimulating and inhibiting doses of X-rays and u.v.-light and the levels of NAD(P), NAD(P)H and hydroxyproline determined during tube growth. Pollen grains irradiated with stimulating doses of X-rays and u.v.-light developed longer tubes, while grains irradiated with inhibiting doses of X-rays and u.v.-light developed shorter tubes than the unirradiated controls. After 32 hr of incubation, the levels of NAD(P), NAD(P)H and hydroxyproline were at their lowest compared with unirradiated pollen. In samples with stimulating doses of irradiation NAD(P) reached its maximum earlier than in samples with inhibiting irradiation. The ratio between the concentrations of NAD(P) and NAD(P)H in the irradiated samples was higher than in the unirradiated control. The hydroxyproline content was higher in irradiated than in unirradiated pollen. (author)

  19. Laser pulse heating of nuclear fuels for simulation of reactor power

    Indian Academy of Sciences (India)

    Laser applications; nuclear fuel elements; nuclear safety. ... accident (LOCA) and reactivity initiated accident (RIA), a laser pulse heating system is under ... As a prelude to work on irradiated nuclear fuel specimens, pilot studies on unirradiated ...

  20. Effect of x-radiation on SERS spectra of chitosan adsorbed on silver nanoparticles with plasmon resonance

    International Nuclear Information System (INIS)

    Motevich, I.G.; Strekal', N.D.; Dul', M.V.; Ganchits, A.T.; Lagun, Yu.Ya.; Melamed, V.D.; Maskevich, S.A.

    2016-01-01

    Chitosan, a deacetylated product of the polysaccharide chitin, is a natural biopolyaminosaccharide obtained from various organisms. Raman and SERS spectra of irradiated and unirradiated chitosan, adsorbed on silver hydrosols, are presented. (authors)

  1. Murine microenvironment metaprofiles associate with human cancer etiology and intrinsic subtypes

    Data.gov (United States)

    National Aeronautics and Space Administration — We developed a mouse model that captures radiation effects on host biology by transplanting unirradiated Trp53 null mammary tissue to sham or irradiated hosts. Gene...

  2. Fractography evaluation of impact and tensile specimens from the HFBR [High Flux Beam Reactor

    International Nuclear Information System (INIS)

    Czajkowski, C.J.

    1989-10-01

    The Materials Technology Group of the Department of Nuclear Energy (DNE) at Brookhaven National Laboratory (BNL) has performed a fractographic examination of neutron irradiated and unirradiated tensile and Charpy ''V'' notch specimens. The evaluation was carried out using a scanning electron microscope (SEM) to evaluate the fracture mode. Photomicrographs were then evaluated to determine the extent of ductility present on the fracture surfaces of the unirradiated specimens. Ductility area measurements ranged from 4.6--9.5% on typical photomicrographs examined. 12 figs

  3. Environmental Assessment: Relocation and storage of TRIGA reg-sign reactor fuel, Hanford Site, Richland, Washington

    International Nuclear Information System (INIS)

    1995-08-01

    In order to allow the shutdown of the Hanford 308 Building in the 300 Area, it is proposed to relocate fuel assemblies (101 irradiated, three unirradiated) from the Mark I TRIGA Reactor storage pool. The irradiated fuel assemblies would be stored in casks in the Interim Storage Area in the Hanford 400 Area; the three unirradiated ones would be transferred to another TRIGA reactor. The relocation is not expected to change the offsite exposure from all Hanford Site 300 and 400 Area operations

  4. Effect of irradiation on vitamin C and acidity

    International Nuclear Information System (INIS)

    Jiravatana, V.

    1971-01-01

    Effect of gamma radiation on the total carbohydrates content of Hom Tong banana stored for various time was discussed. The total carbohydrates of unirradiated banana increased more rapidly during storage than those of irradiated ones. Radiation did not appear to have any effect on the total carbohydrate content in the banana. No significant difference was found on the total carbohydrates between irradiated and unirradiated banana at the same stage of ripeness

  5. Reassessment of the basis for NRC fuel damage criteria for reactivity transients

    International Nuclear Information System (INIS)

    McCardell, R.K.

    1994-01-01

    The present basis for NRC Fuel Damage Criteria was obtained from experiments performed in the Special Power Excursion Reactor Test (SPERT) IV Reactor Capsule Driver Core (CDC) at the Idaho National Engineering Laboratory (INEL) between 1967 and 1970. Most of the CDC test fuel rods were previously unirradiated and the failure threshold for these unirradiated fuel rods was measured to be about 200 calories per gram of UO 2 radially averaged fuel enthalpy at the axial peak

  6. Preliminary investigation on the extension of shelf-life of boiled Chub mackerel by irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Loaharanu, P; Prombubesara, C; Songprasertchai, S

    1971-12-31

    The influence of irradiation on the extension of shelf-life of boiled Chub mackerel stored at room temperature (25-30{sup 0}C) was investigated. It was found that boiled Chub mackerel irradiated at 0.1, 0.2, or 0.3 Mrad could be kept with good organoleptic properties at room temperature for 5, 8, and 11 days respectively; while the unirradiated sample could be kept for only 2 days. Boiled Chub mackerel used in this study was found to be heavily contaminated with microorganisms. Irradiation at doses mentioned caused reduction of more than 99% of bacteria. Bacillus and Acinetobacter were found to predominate in the irradiated boiled mackerel. The predominant flora in unirradiated boiled mackerel included Micrococcus, Staphylococcus, Bacillus, Acinetobacter, and Proteus. E. coli was always detected in unirradiated samples and was occasionally detected only in samples irradiated at 0.1 Mrad. Trimethylamine nitrogen (TMA-N) content, total volatile basic nitrogen (TVB-N) content, and total bacterial count (TBC) were used as indices of decomposition of both irradiated and unirradiated samples. TMA-N and TBC were found to be good indices of quality of only unirradiated boiled Chub mackerel, whereas TVB-N was found to be a good index of quality of both irradiated and unirradiated samples.

  7. Development of a radiochemical method for analyzing radon gas in uranium mine atmospheres: covering the period February 3, 1975--March 31, 1976

    Energy Technology Data Exchange (ETDEWEB)

    Stein, L.; Shearer, J.A.; Hohorst, F.A.; Markun, F.

    1977-01-14

    A simplified radiochemical method has been developed for quantitatively analyzing radon gas in underground uranium mines. In this method, a measured volume of air is drawn by a pump through a drying tube and a cartridge containing dioxygenyl hexafluoroantimonate reagent. Radon is captured as a nonvolatile product. After radioactive equilibrium has been established between radon and its short-lived daughters (approximately 4 hours), the gamma-emission of the cartridge is measured with a scintillation counter. The amount of radon is then calculated from the gamma-emission rate. The effect of cartridge geometry, reagent load, and air flow rate upon collection efficiency and counting efficiency is reported.

  8. Snubber assembly for a control rod drive

    International Nuclear Information System (INIS)

    Matthews, J.C.

    1978-01-01

    A snubber cartridge assembly is mounted to the nozzle of a control rod drive mechanism to insure that the snubber assembly will be located within the liquid filled section of a nuclear reactor vessel whenever the control rod drive is assembled thereto. The snubber assembly includes a piston mounted proximate to the control rod connecting end of the control rod drive leadscrew to allow the piston to travel within the liquid filled snubber cartridge and controllably exhaust liquid therefrom during a ''scram'' condition. The snubber cartridge provides three separate areas of increasing resistance to piston travel to insure a speedy but safe ''scram'' of the control rod into the reactor

  9. Development of a radiochemical method for analyzing radon gas in uranium mine atmospheres: covering the period February 3, 1975--March 31, 1976

    International Nuclear Information System (INIS)

    Stein, L.; Shearer, J.A.; Hohorst, F.A.; Markun, F.

    1977-01-01

    A simplified radiochemical method has been developed for quantitatively analyzing radon gas in underground uranium mines. In this method, a measured volume of air is drawn by a pump through a drying tube and a cartridge containing dioxygenyl hexafluoroantimonate reagent. Radon is captured as a nonvolatile product. After radioactive equilibrium has been established between radon and its short-lived daughters (approximately 4 hours), the gamma-emission of the cartridge is measured with a scintillation counter. The amount of radon is then calculated from the gamma-emission rate. The effect of cartridge geometry, reagent load, and air flow rate upon collection efficiency and counting efficiency is reported

  10. Snubber assembly for a control rod drive

    International Nuclear Information System (INIS)

    1976-01-01

    A snubber cartridge assembly is described which is mounted to the nozzle of a control rod drive mechanism to insure that it will be located within the liquid filled section of a nuclear reactor vessel whenever the control rod drive is assembled thereto. The snubber assembly includes a piston-mounted proximate to the control rod connecting end of the control rod drive leadscrew to allow the piston to travel within the liquid filled snubber cartridge and controllable exhaust the liquid during a 'scram' condition. The snubber cartridge provides three separate areas of increasing resistance to piston travel to insure a speedy but safe 'scram' of the control rod into the reactor

  11. Water reactive hydrogen fuel cell power system

    Science.gov (United States)

    Wallace, Andrew P; Melack, John M; Lefenfeld, Michael

    2014-01-21

    A water reactive hydrogen fueled power system includes devices and methods to combine reactant fuel materials and aqueous solutions to generate hydrogen. The generated hydrogen is converted in a fuel cell to provide electricity. The water reactive hydrogen fueled power system includes a fuel cell, a water feed tray, and a fuel cartridge to generate power for portable power electronics. The removable fuel cartridge is encompassed by the water feed tray and fuel cell. The water feed tray is refillable with water by a user. The water is then transferred from the water feed tray into a fuel cartridge to generate hydrogen for the fuel cell which then produces power for the user.

  12. Highly reproducible polyol synthesis for silver nanocubes

    Science.gov (United States)

    Han, Hye Ji; Yu, Taekyung; Kim, Woo-Sik; Im, Sang Hyuk

    2017-07-01

    We could synthesize the Ag nanocubes highly reproducibly by conducting the polyol synthesis using HCl etchant in dark condition because the photodecomposition/photoreduction of AgCl nanoparticles formed at initial reaction stage were greatly depressed and consequently the selective self-nucleation of Ag single crystals and their selective growth reaction could be promoted. Whereas the reproducibility of the formation of Ag nanocubes were very poor when we synthesize the Ag nanocubes in light condition due to the photoreduction of AgCl to Ag.

  13. 40 CFR 721.5700 - Pentanenitrile, 3-amino-.

    Science.gov (United States)

    2010-07-01

    ...), (a)(5)(xiii), (a)(5)(xiv), and (a)(5)(xv) apply following submittal by the company, and written approval by the EPA, of the results of cartridge service life testing performance in accordance with...

  14. IX Disposition Project - project management plan

    International Nuclear Information System (INIS)

    Choi, I.G.

    1994-01-01

    This report presents plans for resolving saving and disposal concerns for ion exchange modules, cartridge filters and columns. This plan also documents the project baselines for schedules, cost, and technical information

  15. Organic carbon movement through two SWRO facilities from source water to pretreatment to product with relevance to membrane biofouling

    KAUST Repository

    Alshahri, Abdullah; Dehwah, Abdullah; Leiknes, TorOve; Missimer, Thomas M.

    2016-01-01

    reductions. The mixed media filtration process was marginally useful in removing some TOC and NOM, but had little effect on TEP removal. Some bacterial regrowth may be occurring in the cartridge filters, but the evidence is inconsistent. Significant

  16. Sun StorageTek T9940 Tape Drive

    CERN Multimedia

    2002-01-01

    Technology allowed reuse of the same data cartridge at higher capacity with later model of the tape drive hence offering significant savings of the media cost. It has been use by the CERN from 2002 to 2008.

  17. Capturing [11C]CO2 for use in aqueous applications

    International Nuclear Information System (INIS)

    Vandehey, Nicholas T.; O’Neil, James P.

    2014-01-01

    We present a simple method for trapping [ 11 C]CO 2 gas and releasing it into a buffered solution using an ion-exchange cartridge. Sodium hydroxide cartridges captured >99% of [ 11 C]CO 2 following NaOH activation. A sodium bicarbonate solution eluted >99% of trapped radioactivity. Trapping [ 11 C]CO 2 directly in small volumes of several solutions was less effective than cartridge methods. The recommended methods allow for fast and simple production of highly concentrated carbon-11 containing aqueous solutions for use in filling phantoms, calibrating detectors, or (bio)geochemical experiments. - Highlights: • An ion exchange resin can trap [ 11 C]CO 2 gas and release it with saturated bicarbonate. • Elution from cartridge requires as little as 300 µL volume, with eluant at pH=10. • SPE trap-and-release provided better results than trapping in solution

  18. Nicotine and tobacco

    Science.gov (United States)

    ... ease your withdrawal symptoms. Health experts warn that e-cigarettes are not a replacement therapy for cigarette smoking. ... not known exactly how much nicotine is in e-cigarette cartridges, because information on labels is often wrong.

  19. Rigorous Mathematical Modeling of an Adsorption System With Electrothermal Regeneration of the Used Adsorbent

    National Research Council Canada - National Science Library

    Petkovska, Menka; Antov-Bozalo, Danijela; Nikacevic, Nikola

    2006-01-01

    The general objective of the project is fundamental mathematical modeling of a complex TSA system with electrothermal desorption step, with absorbers assembled of one or more cartridge-type, radial...

  20. 75 FR 70246 - Lead Fishing Sinkers; Disposition of TSCA Section 21 Petition

    Science.gov (United States)

    2010-11-17

    ...'s decision was based on the exclusion of shells and cartridges from the definition of ``chemical.... Kentucky Department of Fish & Wildlife Resources Tourism, Art and Heritage Cabinet. Letter to Honorable...

  1. Magnetic Method for DNA Detection on an Arrayed Solid State Device

    National Research Council Canada - National Science Library

    Tamanaha, C. R; Colton, R. J; Miller, M. M; Piani, M. A; Rife, J. C; Sheehan, P. E; Whitman, L. J

    2001-01-01

    .... In addition to the electromagnetic instrumentation, surface chemistries and assays have been developed, as well as a cartridge-based microfluidics network in which pumps and valves are operated...

  2. Apparatus for filtering radioactive fluids

    International Nuclear Information System (INIS)

    Gischel, E.H.

    1975-01-01

    Apparatus is provided for filtering radioactive particles from the cooling and/or auxiliary process water of a nuclear reactor, or nuclear fuel processing plant, or other installations wherein radioactive fluid systems are known to exist. The apparatus affords disposal of the captured particles in a manner which minimizes the exposure of operating personnel to radioactivity. The apparatus comprises a housing adapted to contain a removable filter cartridge assembly, a valve normally closing the lower end of the housing, an upwardly-open shipping cask located below the valve, and an elongated operating rod assembly projecting upwardly from the filter cartridge assembly and through the upper end of the housing to enable a workman to dismount the filter cartridge assembly from its housing and to lower the filter cartridge assembly through the valve and into the cask from a remote location above the housing. (U.S.)

  3. 21 CFR 876.5600 - Sorbent regenerated dialysate delivery system for hemodialysis.

    Science.gov (United States)

    2010-04-01

    ... dialyzer. The device is used with the extracorporeal blood system and the dialyzer of the hemodialysis... dialysate conditions. The sorbent cartridge may include absorbent, ion exchange and catalytic materials. (b...

  4. Travelers' Health: Cryptosporidiosis

    Science.gov (United States)

    ... associated diarrhea; cryptosporidiosis was associated with travel to Asia, particularly India, and Latin America. Another study found ... immunochromatographic cartridge assays, and microscopy with modified acid-fast staining. ... and water precautions (see Chapter 2, Food & Water ...

  5. Extending EV Range with Direct Methanol Fuel Cells

    OpenAIRE

    Steckmann, Kai

    2009-01-01

    Electric cars are the vehicles of the future, and there is a proven hybrid system for extending their mileage. Direct methanol fuel cells (DMFCs) provide safe, lightweight, onboard battery charging that can free car owners from worry about running out of power. The hybrid system includes a DMFC fuel cell, fuel cell cartridge and electric vehicle batteries. The fuel cell operates almost silently with virtually no exhaust, it is immune to extreme weather and the convenient fuel cartridges featu...

  6. Comparison of iSTAT and EPOC Blood Analyzers

    Science.gov (United States)

    2017-10-25

    gold standard laboratory testing to two POC devices—iSTAT and EPOC—with and without expired cartridges and conditioned cartridges. The study was...analysis across a range of environmental conditions and, in extreme circumstances, use beyond the expiration date. We compared gold standard laboratory...BE) extra cellular fluid, BE blood, sulfur dioxide, Hgb) to gold standard measurements conducted by the central laboratory. The study also compared

  7. Optimization of filter loading

    International Nuclear Information System (INIS)

    Turney, J.H.; Gardiner, D.E.; Sacramento Municipal Utility District, Herald, CA)

    1985-01-01

    The introduction of 10 CFR Part 61 has created potential difficulties in the disposal of spent cartridge filters. When this report was prepared, Rancho Seco had no method of packaging and disposing of class B or C filters. This work examined methods to minimize the total operating cost of cartridge filters while maintaining them below the class A limit. It was found that by encapsulating filters in cement the filter operating costs could be minimized

  8. Hazard categorization of K Basin water filtration upgrade project

    International Nuclear Information System (INIS)

    Conn, K.R.

    1995-01-01

    This supporting document provides the hazards categorization for the K Basin Water Filtration Upgrade Project at K East. All activities associated with the project are less than Hazard Category 3, except for the handling of the ECO-ROK liners containing spent filter cartridges. All activities involving the handling of liners, containing spent cartridges, by monorail, forklift or mobile crane are classified as Hazard Category 3

  9. Construction of a Liposome Dialyzer for preparation of high-value, small-volume liposome formulations

    OpenAIRE

    Adamala, Katarzyna; Engelhart, Aaron E.; Kamat, Neha P.; Jin, Lin; Szostak, Jack W.

    2015-01-01

    The liposome dialyzer is a small-volume equilibrium dialysis device, built from commercially available materials, that is designed for rapid exchange of small volumes of an extraliposomal reagent pool against a liposome preparation. The dialyzer is prepared by modification of commercially available dialysis cartridges and consists of a reactor with two 300 µL chambers and a 1.56 cm2 dialysis surface area. The dialyzer is prepared in three stages: 1) disassembly of dialysis cartridges to obtai...

  10. Bystander apoptosis in human cells mediated by irradiated blood plasma

    Energy Technology Data Exchange (ETDEWEB)

    Vinnikov, Volodymyr, E-mail: vlad.vinnikov@mail.ru [Grigoriev Institute for Medical Radiology of the National Academy of Medical Science of Ukraine (Ukraine); Lloyd, David; Finnon, Paul [Centre for Radiation, Chemical and Environmental Hazards of the Health Protection Agency of the United Kingdom (United Kingdom)

    2012-03-01

    Following exposure to high doses of ionizing radiation, due to an accident or during radiotherapy, bystander signalling poses a potential hazard to unirradiated cells and tissues. This process can be mediated by factors circulating in blood plasma. Thus, we assessed the ability of plasma taken from in vitro irradiated human blood to produce a direct cytotoxic effect, by inducing apoptosis in primary human peripheral blood mononuclear cells (PBM), which mainly comprised G{sub 0}-stage lymphocytes. Plasma was collected from healthy donors' blood irradiated in vitro to 0-40 Gy acute {gamma}-rays. Reporter PBM were separated from unirradiated blood with Histopaque and held in medium with the test plasma for 24 h at 37 Degree-Sign C. Additionally, plasma from in vitro irradiated and unirradiated blood was tested against PBM collected from blood given 4 Gy. Apoptosis in reporter PBM was measured by the Annexin V test using flow cytometry. Plasma collected from unirradiated and irradiated blood did not produce any apoptotic response above the control level in unirradiated reporter PBM. Surprisingly, plasma from irradiated blood caused a dose-dependent reduction of apoptosis in irradiated reporter PBM. The yields of radiation-induced cell death in irradiated reporter PBM (after subtracting the respective values in unirradiated reporter PBM) were 22.2 {+-} 1.8% in plasma-free cultures, 21.6 {+-} 1.1% in cultures treated with plasma from unirradiated blood, 20.2 {+-} 1.4% in cultures with plasma from blood given 2-4 Gy and 16.7 {+-} 3.2% in cultures with plasma from blood given 6-10 Gy. These results suggested that irradiated blood plasma did not cause a radiation-induced bystander cell-killing effect. Instead, a reduction of apoptosis in irradiated reporter cells cultured with irradiated blood plasma has implications concerning oncogenic risk from mutated cells surviving after high dose in vivo irradiation (e.g. radiotherapy) and requires further study.

  11. Bystander apoptosis in human cells mediated by irradiated blood plasma

    International Nuclear Information System (INIS)

    Vinnikov, Volodymyr; Lloyd, David; Finnon, Paul

    2012-01-01

    Following exposure to high doses of ionizing radiation, due to an accident or during radiotherapy, bystander signalling poses a potential hazard to unirradiated cells and tissues. This process can be mediated by factors circulating in blood plasma. Thus, we assessed the ability of plasma taken from in vitro irradiated human blood to produce a direct cytotoxic effect, by inducing apoptosis in primary human peripheral blood mononuclear cells (PBM), which mainly comprised G 0 -stage lymphocytes. Plasma was collected from healthy donors’ blood irradiated in vitro to 0–40 Gy acute γ-rays. Reporter PBM were separated from unirradiated blood with Histopaque and held in medium with the test plasma for 24 h at 37 °C. Additionally, plasma from in vitro irradiated and unirradiated blood was tested against PBM collected from blood given 4 Gy. Apoptosis in reporter PBM was measured by the Annexin V test using flow cytometry. Plasma collected from unirradiated and irradiated blood did not produce any apoptotic response above the control level in unirradiated reporter PBM. Surprisingly, plasma from irradiated blood caused a dose-dependent reduction of apoptosis in irradiated reporter PBM. The yields of radiation-induced cell death in irradiated reporter PBM (after subtracting the respective values in unirradiated reporter PBM) were 22.2 ± 1.8% in plasma-free cultures, 21.6 ± 1.1% in cultures treated with plasma from unirradiated blood, 20.2 ± 1.4% in cultures with plasma from blood given 2–4 Gy and 16.7 ± 3.2% in cultures with plasma from blood given 6–10 Gy. These results suggested that irradiated blood plasma did not cause a radiation-induced bystander cell-killing effect. Instead, a reduction of apoptosis in irradiated reporter cells cultured with irradiated blood plasma has implications concerning oncogenic risk from mutated cells surviving after high dose in vivo irradiation (e.g. radiotherapy) and requires further study.

  12. Repair and mutagenesis of herpes simplex virus in UV-irradiated monkey cells

    International Nuclear Information System (INIS)

    Lytle, C.D.; Goddard, J.G.; Lin, C.H.

    1980-01-01

    Mutagenic repair in mammalian cells was investigated by determining the mutagenesis of UV-irradiated or unirradiated herpes simplex virus in UV-irradiated CV-1 monkey kidney cells. These results were compared with the results for UV-enhanced virus reactivation (UVER) in the same experimental situation. High and low multiplicities of infection were used to determine the effects of multiplicity reactivation (MR). UVER and MR were readily demonstrable and were approximately equal in amount in an infectious center assay. For this study, a forward-mutation assay was developed to detect virus mutants resistant to iododeoxycytidine (ICdR), probably an indication of the mutant virus being defective at its thymidine kinase locus. ICdR-resistant mutants did not have a growth advantage over wild-type virus in irradiated or unirradiated cells. Thus, higher fractions of mutant virus indicated greater mutagenesis during virus repair and/or replication. The data showed that: (1) unirradiated virus was mutated in unirradiated cells, providing a background level of mutagenesis; (2) unirradiated virus was mutated about 40% more in irradiated cells, indicating that virus replication (DNA synthesis) became more mutagenic as a result of cell irradiation; (3) irradiated virus was mutated much more (about 6-fold) than unirradiated virus, even in unirradiated cells; (4) cell irradiation did not change the mutagenesis of irradiated virus except at high multiplicity of infection. High multiplicity of infection did not demonstrate UVER or MR alone to be either error-free or error-prone. When the two processes were present simultaneously, they were mutagenic. (orig.)

  13. Development and characterization of a novel plug and play liquid chromatography-mass spectrometry (LC-MS) source that automates connections between the capillary trap, column, and emitter.

    Science.gov (United States)

    Bereman, Michael S; Hsieh, Edward J; Corso, Thomas N; Van Pelt, Colleen K; Maccoss, Michael J

    2013-06-01

    We report the development and characterization of a novel, vendor-neutral ultra-high pressure-compatible (~10,000 p.s.i.) LC-MS source. This device is the first to make automated connections with user-packed capillary traps, columns, and capillary emitters. The source uses plastic rectangular inserts (referred to here as cartridges) where individual components (i.e. trap, column, or emitter) can be exchanged independent of one another in a plug and play manner. Automated robotic connections are made between the three cartridges using linear translation powered by stepper motors to axially compress each cartridge by applying a well controlled constant compression force to each commercial LC fitting. The user has the versatility to tailor the separation (e.g. the length of the column, type of stationary phase, and mode of separation) to the experimental design of interest in a cost-effective manner. The source is described in detail, and several experiments are performed to evaluate the robustness of both the system and the exchange of the individual trap and emitter cartridges. The standard deviation in the retention time of four targeted peptides from a standard digest interlaced with a soluble Caenorhabditis elegans lysate ranged between 3.1 and 5.3 s over 3 days of analyses. Exchange of the emitter cartridge was found to have an insignificant effect on the abundance of various peptides. In addition, the trap cartridge can be replaced with minimal effects on retention time (<20 s).

  14. Effect of gamma irradiation on microbiological, chemical and sensory characteristics of aniseed (pimpinella anisum)

    International Nuclear Information System (INIS)

    Al-Bachir, M.

    2007-01-01

    Seeds of anise (pimpinella anisum) were exposed to doses of 0, 5, 10, 15 and 20 kGy in a 60 Co package irradiator. Irradiated and unirradiated samples were stored at room temperature. Microbial population on seeds, total and inorganic soluble solids in water extract and sensory properties of the latter were evaluated after 0, 6 and 12 months of storage. The results indicated that gamma irradiation reduced the aerobic plate counts of aniseed. Immediately after irradiation, the total soluble solids in an extract of irradiated seeds were greater than those of unirradiated ones. The total soluble solids in an extract of irradiated and un-irradiated seeds increased after 6 and 12 months of storage. There were no significant differences (p>0.05) in inorganic soluble solids between the water extract of irradiated and unirradiated aniseeds. Sensory evaluation indicated that gamma irradiation improved sensory characteristics of aniseed water extract tested immediately after irradiation. However, after 12 months of storage, no significant differences (P>0.05) were found in color, taste or flavor between extract of irradiated and unirradiated seeds. (author)

  15. Immune sensitization against epidermal antigens in polymorphous light eruption

    International Nuclear Information System (INIS)

    Gonzalez-Amaro, R.; Baranda, L.; Salazar-Gonzalez, J.F.; Abud-Mendoza, C.; Moncada, B.

    1991-01-01

    To get further insight into the pathogenesis of polymorphous light eruption, we studied nine patients with polymorphous light eruption and six healthy persons. Two skin biopsy specimens were obtained from each person, one from previously ultraviolet light-irradiated skin and another one from unirradiated skin. An epidermal cell suspension, skin homogenate, or both were prepared from each specimen. Autologous cultures were made with peripheral blood mononuclear cells combined with irradiated or unirradiated skin homogenate and peripheral blood mononuclear cells combined with irradiated or unirradiated epidermal cell suspension. Cell proliferation was assessed by 3H-thymidine incorporation assay. The response of peripheral blood mononuclear cells to unirradiated epidermal cells or unirradiated skin homogenate was similar in both patients and controls. However, peripheral blood mononuclear cells from patients with polymorphous light eruption showed a significantly increased proliferative response to both irradiated epidermal cells and irradiated skin homogenate. Our results indicate that ultraviolet light increases the stimulatory capability of polymorphous light eruption epidermal cells in a unidirectional mixed culture with autologous peripheral blood mononuclear cells. This suggests that an immune sensitization against autologous ultraviolet light-modified skin antigens occurs in polymorphous light eruption

  16. Application of gamma irradiation for storage potato

    International Nuclear Information System (INIS)

    Rezaee, M.; Almasi, M.

    2009-01-01

    Since deficiency of controlled store in Iran and environmental problems of chemical material the use of gamma irradiation to control sprouting and increase the length of storage time of potatoes has been proposed as an alternative to cold storage or the use of chemical sprout suppressants. In this study potatoes of Agria Variety were irradiated at a dose of 0.10 KGY and stored along with the unirradiated controls at 12±3°C for a period of more than 6 month from October to April .After 4 month of storage the sprouting ranged from 5 to 12% in irradiated potatoes and 45 to 74% in unirradiated samples and after 6 month the unirradiated potatoes were discarded because of heavy sprouting and rotting. The rot attack was approximately double in unirradiated samples. It was found that losses through dehydration were 10.3 to 15.1 % in the irradiated potatoes. Also a comparative study of reducing and non-reducing sugars, vitamin-C content, total sugar, starch and protein was carried out between unirradiated and irradiated samples. The results suggested the efficacy of Gamma irradiation for ensuring availability of the storing quality of potato during lean periods from October to April. (author)

  17. A neural network to improve dim-light vision? Dendritic fields of first-order interneurons in the nocturnal bee Megalopta genalis.

    Science.gov (United States)

    Greiner, Birgit; Ribi, Willi A; Warrant, Eric J

    2005-11-01

    Using the combined Golgi-electron microscopy technique, we have determined the three-dimensional dendritic fields of the short visual fibres (svf 1-3) and first-order interneurons or L-fibres (L1-4) within the first optic ganglion (lamina) of the nocturnal bee Megalopta genalis. Serial cross sections have revealed that the svf type 2 branches into one adjacent neural unit (cartridge) in layer A, the most distal of the three lamina layers A, B and C. All L-fibres, except L1-a, exhibit wide lateral branching into several neighbouring cartridges. L1-b shows a dendritic field of seven cartridges in layers A and C, dendrites of L2 target 13 cartridges in layer A, L3 branches over a total of 12 cartridges in layer A and three in layer C and L4 has the largest dendritic field size of 18 cartridges in layer C. The number of cartridges reached by the respective L-fibres is distinctly greater in the nocturnal bee than in the worker honeybee and is larger than could be estimated from our previous Golgi-light microscopy study. The extreme dorso-ventrally oriented dendritic field of L4 in M. genalis may, in addition to its potential role in spatial summation, be involved in edge detection. Thus, we have shown that the amount of lateral spreading present in the lamina provides the anatomical basis for the required spatial summation. Theoretical and future physiological work should further elucidate the roles that this lateral spreading plays to improve dim-light vision in nocturnal insects.

  18. Radiation Induced Treatment of Organic Pollutants

    International Nuclear Information System (INIS)

    Ergun, E.; Öztürk, Ş.; Kantoğlu, Ö.

    2012-01-01

    In this period of the research, aerobic and anaerobic digestion, characterization of alkaloids present and radiolysis products formed after irradiation, under different conditions of ambient and additives, optimization of dose to achieve desired end characteristics for discharge of waste water were aimed. In this regard, unirradiated and irradiated wastewaters were subjected to aerobic and anaerobic digestions. Substrate removal efficiencies of unirradiated and irradiated wastewater with various initial COD values were determined with SBR aerobic digestion treatment method. On the other hand Fenton’s advanced oxidation treatment method was also applied for pre-treatment. BMP tests of anaerobic digestion were also completed. LC/MS studies were carried out on unirradiated and irradiated alkaloid standard solutions of morphine, codeine, thebaine, papaverine, and noscapine to determine the degradation mechanisms and byproducts. Dose optimization studies were completed and found to be a lower dose of 5 kGy rather than 40 kGy for ambient irradiation conditions. (author)

  19. Radiation Induced Treatment of Organic Pollutants

    Energy Technology Data Exchange (ETDEWEB)

    Ergun, E.; Öztürk, Ş.; Kantoğlu, Ö. [Turkish Atomic Energy Authority, Sarayköy Nuclear research and Training Center, Ankara (Turkey)

    2012-07-01

    In this period of the research, aerobic and anaerobic digestion, characterization of alkaloids present and radiolysis products formed after irradiation, under different conditions of ambient and additives, optimization of dose to achieve desired end characteristics for discharge of waste water were aimed. In this regard, unirradiated and irradiated wastewaters were subjected to aerobic and anaerobic digestions. Substrate removal efficiencies of unirradiated and irradiated wastewater with various initial COD values were determined with SBR aerobic digestion treatment method. On the other hand Fenton’s advanced oxidation treatment method was also applied for pre-treatment. BMP tests of anaerobic digestion were also completed. LC/MS studies were carried out on unirradiated and irradiated alkaloid standard solutions of morphine, codeine, thebaine, papaverine, and noscapine to determine the degradation mechanisms and byproducts. Dose optimization studies were completed and found to be a lower dose of 5 kGy rather than 40 kGy for ambient irradiation conditions. (author)

  20. Influence of conditioned psychological stress on immunological recovery in mice exposed to low-dose x irradiation

    International Nuclear Information System (INIS)

    Sato, K.; Flood, J.F.; Makinodan, T.

    1984-01-01

    A study was initiated to determine the effects of psychological stress on the immune response in BALB/c mice recovering from exposure to a low dose of ionizing radiation. Mice were first subjected to conditioning training for 12 days, then exposed to 200 R, subjected to psychological stress for 14 days, and assessed for peak anti-sheep RBC response. The seven treatment groups included two unirradiated groups and five irradiated groups. Mice exposed to 200 R and then subjected to conditioned psychological stress responded less vigorously to antigenic stimulation than those of the other irradiated groups. The psychological stress imposed upon these mice did not influence the antibody-forming capacity of unirradiated mice. These results indicate that a psychological stress which did not affect the immunological activity of unirradiated mice can curtail the immunological recovery of mice exposed to low doses of ionizing radiation

  1. Bystander effects on mammalian cells induced by carbon ions

    International Nuclear Information System (INIS)

    Wang Jufang; Zhao Jing; Ma Qiufeng; Chinese Academy of Sciences, Beijing; Li Weijian; Zhou Guangming; Dang Bingrong; Mao Limin; Feng Yan

    2004-01-01

    Bystander effects on unirradiated V79 cells were observed by irradiated conditioned medium (ICM) method and co-cultured with carbon-ion-irradiated V79 cells. The results showed that the colony formation efficiency of unirradiated cells is obviously decreased by ICM. After co-culture with carbon-ion-irradiated cells for some time, the colony formation efficiency of co-cultured cells was lower than expected results assuming no bystander effects. The micronucleus frequency and hprt gene mutation rate was almost the same as expected results. Cytotoxic factor(s), which was effective for cell growth but not for micronucleus and mutation on unirradiated cells, might be released by irradiated cells. (authors)

  2. Study on creep-fatigue life of irradiated austenitic stainless steel

    International Nuclear Information System (INIS)

    Ioka, Ikuo; Miwa, Yukio; Tsuji, Hirokazu; Yonekawa, Minoru; Takada, Fumiki; Hoshiya, Taiji

    2001-01-01

    The low cycle creep-fatigue test with tensile strain hold of the austenitic stainless steel irradiated to 2 dpa was carried out at 823K in vacuum. The applicability of creep-fatigue life prediction methods to the irradiated specimen was examined. The fatigue life on the irradiated specimen without tensile strain hold time was reduced by a factor of 2-5 in comparison with the unirradiated specimen. The decline in fatigue life of the irradiated specimen with tensile strain hold was almost equal to that of the unirradiated specimen. The creep damage of both unirradiated and irradiated specimens was underestimated by the time fraction rule or the ductility exhaustion rule. The creep damage calculated by the time fraction rule or the ductility exhaustion rule increased by the irradiation. The predictions derived from the linear damage rule are unsafe as compared with the experimental fatigue lives. (author)

  3. Mating competitiveness and the effect of X-rays and aging on males of Tetranychus urticae (Acarina, Tetranychidae) in relation to genetic control

    International Nuclear Information System (INIS)

    Feldmann, A.M.

    1977-01-01

    Males of Tetranychus urticae Koch were irradiated with X-ray doses of 4, 8, 24 and 32 krad (which were applied to 0-1 day-old adult virgin males) and tested in mating competition with one-day-old non-irradiated males. A non-significant excess of parental females were mated to the unirradiated males. This consistent trend in favour of females, mated with unirradiated males was highly significant, when the results of all the experiments were bulked. This indicated that radiation impaired the mating competitiveness of males of T. urticae. Aging of irradiated males resulted in a significant decrease of male-mating competitiveness at least within 2 days after irradiation. When 24 krad X-rays irradiated males were tested in mating competition at different ages, with unirradiated males of equal age, it was demonstrated that the reduction in mating competitiveness of aging irradiated males is caused by accelerated aging due to the irradiation treatment

  4. Lifespan studies on different strains of mice exposed chronically to low levels of whole body gamma irradiation

    International Nuclear Information System (INIS)

    Fox, L.A.; Klein, A.K.; Cain, G.R.; Rosenblatt, L.S.

    1982-01-01

    Several strains of mice, chosen for their predisposition to immunohematological disorders, were exposed to low levels of 60 irradiation continuously for four weeks. All individuals were subsequently followed throughout their lifetimes. W/W/sup v/ mice, which are tyically subject to a stem cell deficiency, had a lower cumulative survival rate for the irradiated group than for the unirradiated controls. Irradiated RF/sub j/ mice had a dramatically lower cumulative survival rate than their unirradiated controls. Conversely, BXSB mice, which have a lumphoproliferative autoimmune disorder, had a higher cumulative survival rate after chronic irradiation than did unirradiated BXSBs. Irradiation had no effect upon the survival rate curves of the NZB strain, the murine model for Lupus Erythematosus

  5. On the Thermal Conductivity Change of Matrix Graphite Materials after Neutron Irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Young-Woo; Yeo, Seunghwan; Kim, Eung-Seon; Sah, Injin; Park, Daegyu; Kim, Youngjun; Cho, Moon Sung [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2016-10-15

    In this work, the variations of the thermal conductivity of the A3-3 matrix graphite after neutron irradiation is discussed as well as of the IG-110 graphite for comparison. Neutron irradiation of the graphite specimens was carried out as a part of the first irradiation test of KAERI's coated particle fuel specimens by use of Hanaro research reactor. This work can be summarized as follows: 1) In the evaluation of the specific heat of the graphite materials, various literature data were used and the variations of the specific heat data of all the graphite specimens are observed well agreed, irrespectively of the difference in specimens (graphite and matrix graphite and irradiated and un-irradiated). 2) This implies that it should be reasonable that for both structural graphite and fuel matrix graphite, and even for the neuron-irradiated graphite, any of these specific heat data set be used in the calculation of the thermal conductivity. 3) For the irradiated A3-3 matrix graphite specimens, the thermal conductivity decreased on both directions. On the radial direction, the tendency of variation upon temperature is similar to that of unirradiated specimen, i.e., decreasing as the temperature increases. 4) In the German irradiation experiments with A3-27 matrix graphite specimens, the thermal conductivity of the un-irradiated specimen shows a decrease and that of irradiated specimen is nearly constant as the temperature increases. 5) The thermal conductivity of the irradiated IG-110 was considerably decreased compared with that of un-irradiated specimens The difference of the thermal conductivity of un-irradiated and irradiated IG-110 graphite specimens is much larger than that of un-irradiated and irradiated A3-3 matrix graphite specimens.

  6. Evidence against a systemic humoral factor controlling the intestinal compensatory response following X-irradiation

    International Nuclear Information System (INIS)

    Sharp, J.G.; Osborne, J.W.; Iowa Univ., Iowa City

    1981-01-01

    The investigation was devised to determine whether changes noted in the unirradiated duodenum and colon of single rats after X-irradiation of only the exteriorized rat jejunum and ileum are mediated by a systemic humoral factor. Littermate Holtzman male rats were joined in parabiosis and one month later, the temporarily exteriorized jejunum and ileum of one member was exposed to 1.000 R of 250 kVp X-irradiation. Two days after X-irradiation, and 1, 12 and 24 h after 1 μCi/g bodyweight 3 H-thymidine was injected i.p. rats were sacrificed and appropriate tissues removed. Single rats which had the exteriorized jejunum and ileum irradiated were studied from 1-3 days after irradiation. Crypt cell migration rates were determined employing autoradiography. Tritium content and columnar cell migration rate in duodenum and colon of unirradiated rats compared to irradiated rats indicated that irradiation of one member of the pair had no effect on tritium incorporation or epithelial cell migration in the duodenum or colon of the unirradiated partner. Epithelial cell proliferation and crypt cell migration were increased in unirradiated duodenum and colon of single intestine-irradiated rats. Essentially the same changes were seen in the irradiated member of a parabiotic pair, but none of these changes were noted in the unirradiated member. The absence of stimulation in the unirradiated parabiont suggests that either a systemic humoral factor is not present after X-irradiation or is not present in sufficient concentration to be detected by these methods. (orig./MG)

  7. Preservation of yams by gamma radiation

    International Nuclear Information System (INIS)

    Bansa, D.; Appiah, V.

    1999-01-01

    Loss of yam in storage due to sprouting is very high. There is the need to investigate the possibility of inhibiting the sprouting of local varieties of yams using gamma radiation. The effect of radiation on the storage yams and the functionality of the irradiated yams in the Ghanaian food system was studied. Yams were purchased from a farm in Nkwanta. Some of the yams were irradiated at an average dose of 120 Gy and a dose rate of 114 Gy/hr. The irradiated yams were stored alongside unirradiated controls in a specially constructed barn and on the ground as is traditionally done by the farmers at ambient temperature for 6 months. The stored yams were processed into some local food products, namely, boiled yam, fried yam and fufu and sensory evaluation carried out on them using the Hedonic Scale Test and analysed by Analysis of variance. Results indicated that all the unirradiated yams sprouted by the 3rd month of storage. 6.2% of the irradiated yams stored on the barn and 18.0% of those stored on the ground sprouted. 2.26% irradiated and 8.0% unirradiated yams stored on the barn compared to 22.0% and 12.0% respectively of the yams stored on the ground got rotten within the storage period. Food products made from irradiated yams were preferred to those made from the unirradiated yams in terms of texture, taste, colour and general acceptability. The results suggest that gamma radiation dose of 120 Gy effectively inhibited the sprouting of yams for 6 months under tropical ambient conditions. There was less rotting in the yams stored in the barn compared to those stored on the ground. There was also less rotting in the irradiated yams stored in the barn in comparison with the unirradiated ones. Food products made from irradiated yams were judged better in quality than those made from the unirradiated ones. (au)

  8. Effects of gamma irradiation dose and timing of treatment after harvest on the storeability of garlic bulbs

    International Nuclear Information System (INIS)

    Kwon, J.H.; Byun, M.W.; Cho, H.O.

    1985-01-01

    The effect of gamma irradiation dose and time of treatment after harvest on the storage of garlic bulbs was investigated. The effectiveness of irradiation for external sprout inhibition was not affected by the treatment time within 45 days after harvest. At 285 days after harvest, irradiation of 50 - 150 Gy caused about 6% less decrease in weight loss compared with the unirradiated group, and spoilage rates of the unirradiated and irradiated cloves were 100% and 17 - 20%, respectively. For the overall storageability of garlic bulbs, 75 Gy was shown to be the minimal optimum dose, and there was no apparent effect depending upon the time of irradiation treatment after harvest

  9. Elevated-temperature tensile properties of 2 1/4 Cr-1 Mo steel irradiated in the EBR-II, AD-2 experiment

    International Nuclear Information System (INIS)

    Klueh, R.L.; Vitek, J.M.

    1984-01-01

    The effect of irradiated on the tensile properties of 2 1/4 Cr-1 Mo steel was determined for specimens irradiation in EBR-II at 390 to 550 0 C. Unirradiated control specimens and specimens aged for 5000 h at the irradiation temperatures were also tested. Irradiation to approximately 9 dpa at 390 0 C increased the strength and decreased the ductility compared with the unirradiated and aged specimens. Softening occurred in samples irradiated and tested at 450, 500, and 550 0 C

  10. Sexual competitiveness of gamma irradiated red flour beetle, tribolium castaneum (herbst)

    International Nuclear Information System (INIS)

    Satar, A.; Khan, A.; Khattak, S.U.; Salihan, Z.

    1989-01-01

    Studies on the sexual competitiveness of radiated male and female adults of tribolium castaneum were conducted under controlled laboratory conditions. The results evaluated on the basis of tendency infertility and competitiveness showed that a ratio of 5:1:1 (Irradiated male/female: Unirradiated male/female: Unirradiated female/male) was the best followed by 4:1:1, 3;1:1, 2:1:1 and 1:1:1 in both the sexes. However, females were found more competitive than male. (author)

  11. Effects of gamma irradiation on the sperm transmission and oviposition response in Helicoverpa armigera (L. Noctuidae)

    International Nuclear Information System (INIS)

    Liu Xiaohui; Wang Huasong; Song Jiaxiang

    1999-12-01

    The transmission of sperm by unirradiated and irradiated cotton bollworm, Helicoverpa armigera, was studied by live dissection of the female immediately after the initiation of mating. In cotton bollworm the sperm transfer was a rather complex process. In fact, the unirradiated male failed to transfer sperm in about 19% of their matings. After being irradiated with 250 Gy and 400 Gy, the aberrations of sperm transmission were about 21% and 50% respectively. The failure of spermatophore 'cap' location was an important reason of sperm transmission aberrations. When female mated to high-dose-irradiated males, its oviposition response appeared abnormal

  12. Herpes simplex virus produces larger plaques when assayed on ultraviolet irradiated CV1 cells

    International Nuclear Information System (INIS)

    Coohill, T.P.; Babich, M.A.; Taylor, W.D.; Snipes, W.

    1980-01-01

    Plaque development for either untreated or UV treated irradiated Herpes simplex virus Type 1 was faster when assayed on UV irradiated CV1 cells. This Large Plaque Effect only occurred if a minimum delay of 12h between cell irradiation and viral inoculation was allowed. Shorter delays gave plaques that were smaller than controls (unirradiated virus-unirradiated cells). The effect was maximal for a 48-h delay and remained unchanged for delays as long as 84h. The effect was greatest for cell exposures of 10Jm -2 . (author)

  13. Effects of fast neutron irradiation on thermal conductivity of Li2O and LiAlO2

    International Nuclear Information System (INIS)

    Ethridge, J.L.; Baker, D.E.

    1987-03-01

    Li 2 O and LiAlO 2 are two candidates for solid breeder materials in the United States' Fusion Power Program. Critical to breeder design efforts are thermophysical data, the bulk of which have only recently become available, for unirradiated lithium ceramics. This paper expands the current limited database by presenting thermal conductivity data between 373-1173K for both materials following fast neutron irradiation. Samples were irradiated at 773-1173K to lithium burnups ≤11.5 /times/ 10 20 captures/cm 3 . Comparisons are made between these data and those from unirradiated archive samples of these same materials. 15 refs., 10 figs., 2 tabs

  14. Radiation-enhanced precipitation in a V-10 wt % Ti alloy

    International Nuclear Information System (INIS)

    Agarwal, S.C.; Taylor, A.

    1976-01-01

    A V-10 wt % Ti alloy was irradiated with 2.7 MeV 51 V + at 650 0 C to doses of 2 to 60 dpa. No void swelling was observed at any dose. The irradiation resulted in an enhancement of a precipitation process similar to that observed in unirradiated materials. The precipitates in irradiated specimens were found to have the NaCl-type cubic crystal structure with a lattice parameter of TiO. The orientation relationship between the matrix and the precipitates was the same as that observed under thermal equilibrium conditions in unirradiated materials

  15. Positron annihilation and thermally stimulated current of electron beam irradiated polyetheretherketone

    Energy Technology Data Exchange (ETDEWEB)

    Fujita, Shigetaka; Shinyama, Katsuyoshi; Baba, Makoto [Hachinohe Inst. of Tech., Hachinohe, Aomori (Japan); Suzuki, Takenori

    1997-03-01

    Positron lifetime measurements were applied to electron beam irradiated poly(ether-ether-ketone). The lifetime, {tau}{sub 3}, of the ortho-positronium of unirradiated and 5 MGy irradiated specimen became rapidly longer above about 150degC. {tau}{sub 3} of 50 MGy and 100 MGy irradiated specimen was shorter than that of unirradiated one. Thermally stimulated current (TSC) decreased with increasing the dose before voltage application. In the case of voltage application, a TSC peak appeared and the peak value decreased with increased the dose. The correlation between the results of positron annihilation and TSC was investigated. (author)

  16. Physico-chemical changes in heavy ions irradiated polymer foils by differential scanning calorimetry

    International Nuclear Information System (INIS)

    Ciesla, K.; Trautmann, Ch.; Vansant, E.F.

    1994-01-01

    The sample of commercial PETP (Hostaphan) and very heavy ions irradiated products were investigated by differential scanning calorimetry in nitrogen flow. Irradiation were performed with Dy ions of 13 MeV/u with fluences 5 x 10 10 ions/cm 2 . Differences were observed in melting behaviour of unirradiated and irradiated foils. The influence of irradiation conditions on the results was noticed. Moreover the samples of polyimide (Kapton) and polycarbonate (Macrofol) irradiated in similar conditions were examined by DSC. The DSC traces have been compared with those of unirradiated reference samples. (author). 8 refs, 5 figs

  17. In-reactor creep rupture of 20% cold-worked AISI 316 stainless steel

    International Nuclear Information System (INIS)

    Lovell, A.J.; Chin, B.A.; Gilbert, E.R.

    1981-01-01

    Results of an experiment designed to measure in-reactor stress-to-rupture properties of 20% cold-worked AISI 316 stainless steel are reported. The in-reactor rupture data are compared with postirradiation and unirradiated test results. In-reactor rupture lives were found to exceed rupture predictions of postirradiation tests. This longer in-reactor rupture life is attributed to dynamic point defect generation which is absent during postirradiation testing. The in-reactor stress-to-rupture properties are shown to be equal to or greater than the unirradiated material stress-to-rupture properties for times up to 7000 h. (author)

  18. Technical assessment of niobium alloys data base for fusion reactor applications

    Energy Technology Data Exchange (ETDEWEB)

    Pionke, L J; Davis, J W

    1979-08-01

    Refractory metals are one class of material to be developed in the Alloy Development For Irradiation Performance (ADIP) program recently initiated. A principal purpose of the assessment reported herein is to establish the existing data base for niobium alloys in order to help guide the work to be performed in the ADIP program. Major ADIP decisions include alloy selection/modification and irradiated/unirradiated material testing. This Assessment addressed the topics of: (1) niobium alloy development history and niobium metallurgy, (2) unirradiated mechanical properties, (3) irradiated properties, (4) corrosion, and (5) environmental effects.

  19. Mutagenicity studies on alcohol extracts from gamma-irradiated potatoes

    International Nuclear Information System (INIS)

    Shibuya, Tohru; Murora, Tetsuro; Iwahara, Shigeo; Hashimoto, Koroku; Minegishi, Atsuko.

    1982-01-01

    Alcohol extracts freshly prepared from gamma-irradiated and unirradiated potatoes were tested for the ability to induce dominant lethals in BDF 1 mice. Male mice were given 0.5 ml of extract twice a day, p.o., for 7 days and then mated with untreated female mice. Female mice were sacrificed on about the 13th day of pregnancy. No significant difference was observed in the number of living inplants between the group treated with extract prepared from unirradiated potatoes and that treated with the extract from 150 Gy (15 krad) irradiated potatoes. (author)

  20. Effect of gamma-ray irradiation on starch in sweet popato roots

    International Nuclear Information System (INIS)

    Hayashi, T.; Todoroki, S.

    1994-01-01

    Starch contents, as well as the size and molecular weight, in sweet potato roots decreased during steerage at 30 degrees C after gamma-ray irradiation, accompanying the increase of sucrose content. No change in the starch and sucrose contents was observed in unirradiated specimens. By microscopy damaged starch granules were observed only in gamma-ray irradiated root. The results suggested that starch was converted into sucrose unirradiated sweet potato roots by the enzymes responsible for starch-sugar interconversion of which the activities were enhanced by gamma-ray irradiation

  1. Protoplast fusion in Streptomyces: fusions involving ultraviolet-irradiated protoplasts

    International Nuclear Information System (INIS)

    Hopwood, D.A.; Wright, H.M.

    1981-01-01

    Protoplasts of Streptomyces coelicolor showed the same ultraviolet killing kinetics as spores. Irradiated protoplasts gave rise to recombinants when they were fused with unirradiated protoplasts of a strain carrying complementary genetic markers. The decline with u.v. fluence in the capacity of irradiated protoplasts to yield recombinants inheriting individual markers was some six times less steep than the survival of unfused protoplasts; thus, for example, protoplasts reduced to only 0.01% survival still yielded 10% as many recombinants as unirradiated protoplasts. Each of six widely separated markers of the irradiated parent was inherited independently of the others, with a frequency falling exponentially with u.v. fluence. (author)

  2. Identification of irradiated spices with luminescence measurements: a European intercomparison

    Energy Technology Data Exchange (ETDEWEB)

    Heide, L; Guggenberger, R; Boegl, K W [Federal Health Office, Neuherberg/Muenchen (Germany, F.R.). Inst. for Radiation Hygiene

    1989-01-01

    Blind tests were performed measuring the thermoluminescence intensity on samples from 10 different spices that were either irradiated or unirradiated. The chemiluminescence was measured on 10 additional spice samples. Twelve institutions participated in this collaborative study. Thresholds were defined which, when exceeded, declare samples as irradiated. The recovering rate was nearly 100% for samples investigated by thermoluminescence. Only one out of 495 irradiated samples was not identified. By using chemiluminescence, the participants succeeded in identifying 99% of unirradiated samples and 75% of irradiated samples from a total of 490 samples. (author).

  3. Detection of 8-hydroxydeoxyguanine in the Irradiated Orange and Spice

    International Nuclear Information System (INIS)

    Alam, Mohammad Khorshed.

    2007-01-01

    A study was carried out to detect the chemical change that might occur in irradiated orange and spice. Oxidative DNA damage can induce the production of 8-hydroxydeoxyguanine (8-OHdG) and thus the level of 8-hydroxydeoxyguanine was investigated using enzyme linked immunosorbent assay (ELISA) in the irradiated orange and spice which was compared with the unirradiated samples. By the difference in the oxidized guanine level that produce 8-hydroxydeoxyguanine in the irradiated and unirradiated samples, it can be clearly understood that detection of irradiated orange and spice is possible using monoclonal antibody for 8-hydroxydeoxyguanine in the ELAISA assay.(author)

  4. Radition-induced genetic damage in plutella xylostella

    International Nuclear Information System (INIS)

    Ismail bin Bahari; Mahani binti Mohamad

    1993-01-01

    Radiation-induced chromosomal aberrations in progenies of irradiated Plutella xylostella was determined in a F1 sterility study. A total of 4 types of crosses (irradiated males against unirradiated females, irradiated females against unirradiated males, both parents irradiated and normal) were made following gamma irradiation at the pupal stage. Testes squash preparations made from F1 male larvae revealed 3 main types of chromosomal abberations induced by doses of 100, 150 and 200 Gy. Results obtained indicate the possibility of using chromosome translocations as the genetic marker

  5. Safe storage of premature maize ears through gamma radiation and irradiation effect on chemical composition

    International Nuclear Information System (INIS)

    Gupta, H.O.; Singh, N.N.; Roy, M.K.

    2003-01-01

    Marked differences were observed between unirradiated and irradiated premature ears (early dough stage) of maize during storage. Some molds were developed on the grains and deterioration set in at the peduncle and stone of maize in the unirradiated ears, whereas no such symptoms were observed in the 3 kGy irradiated ears even after 45 days of storage. Changes in chemical constituents viz. starch, protein, total sugars were observed in the ears without adversely affecting the quality traits through radiation although 100 grains weight reduced slightly. (author)

  6. Nuclear scaffold organization in the X-ray sensitive Chinese hamster mutant cell line, xrs-5

    International Nuclear Information System (INIS)

    Yasui, L.S.; Fink, T.J.; Enrique, A.M.

    1994-01-01

    Nuclear organization was probed in the radiation-sensitive Chinese hamster ovary (CHO) cell line, xrs-5, and compared with parental CHO K1 cells using the resinless section technique and DNase I digestions. The resinless section data showed no gross morphological differences in core filaments from the nuclear scaffolds of unirradiated CHO K1 and xrs-5 cells. However, the nuclear scaffolds of irradiated xrs-5 cells (1 Gy) had significantly increased ground substance. Irradiated and unirradiated CHO K1 cell nuclear scaffolds were morphologically identical. These data suggest that both CHO K1 and xrs-5 cell nuclear scaffolds had internal nuclear scaffolding networks that could provide DNA attachment sites. (author)

  7. Estimates of health risks associated with uranium transportation by air

    International Nuclear Information System (INIS)

    Elert, M.; Skagius, K.; Ericsson, A.M.; Karlsson, L.G.; Markstroem, A.

    1989-01-01

    There is today an increased interest for air transport of large quantities of uranium compounds. In this report the health risks from an aircrash where uraniumhexafluoride, uraniumdioxide powder, low enriched unirradiated fuel used in Swedish power reactors and unirradiated MTR-fuel used in the research reactor in Studsvik, is analysed. The radiation doses to personnel and the general public is calculated as well as the ground contamination from the spreaded material. Also air concentration of hydrogenflouride, from uraniumhexaflouride reacting with moisture in the air, is calculated. A number of intermediate results are presented. (authors) (69 refs.)

  8. Irradiation effect on onion keeping-quality after sea-shipment from Argentina to the Netherlands

    International Nuclear Information System (INIS)

    Wolters, T.C.; Langerak, D.I.; Curzio, O.A.; Croci, C.A.

    1990-01-01

    Onion losses occur due to sprouting and rot. Onion cultivar Valenciana was irradiated with 60 Gy, shipped from Argentina to the Netherlands, and stored 6 months at 4 degrees C. The rot in unirradiated samples increased after 4 months while rot in irradiated samples remained almost constant. Irradiation almost completely prevented sprouting. Storage losses were 50% for unirradiated and 20% for irradiated samples. Irradiated samples showed an improvement in general appearance. Irradiation reduced weight loss and damaged bulbs were more susceptible to storage rot

  9. Effects of gamma irradiation on antioxidants and ultraviolet stabilizers

    International Nuclear Information System (INIS)

    Kawamura, Yoko; Miura, Makiko; Miura, Yukiko; Yamada, Takashi

    1998-01-01

    The effects of gamma irradiation on 18 kinds of antioxidants and 10 kinds of ultraviolet stabilizers, intact or in a polyethylene sheet, were studied. After irradiating at a 30kGy dose, the content of additives themselves did not change and new degradation products were not found. While most antioxidants in polyethylene had a decreased content after irradiation, most ultraviolet stabilizers did not change. During the migration tests with aqueous food simulants, additives were not released from either irradiated or unirradiated sheets. For the migration tests with n-heptane, however, all additives were released from the unirradiated sheet, while most of the antioxidants were not released or released only slightly. (author)

  10. Heat shock and herpes virus: enhanced reactivation without untargeted mutagenesis

    International Nuclear Information System (INIS)

    Lytle, C.D.; Carney, P.G.

    1988-01-01

    Enhanced reactivation of Ultraviolet-irradiated virus has been reported to occur in heat-shocked host cells. Since enhanced virus reactivation is often accompanied by untargeted mutagenesis, we investigated whether such mutagenesis would occur for herpes simplex virus (HSV) in CV-1 monkey kidney cells subjected to heat shock. In addition to expressing enhanced reactivation, the treated cells were transiently more susceptible to infection by unirradiated HSV. No mutagenesis of unirradiated HSV was found whether infection occurred at the time of increased susceptibility to infection or during expression of enhanced viral reactivation

  11. Irradiation processing of potatoes, onions and garlic

    International Nuclear Information System (INIS)

    Jan, M.; Starr, A.; Wahid, M.; Ahmad, A.; Khan, I.

    1992-07-01

    In this report, studies have been conducted on irradiation preservation of potatoes, onions and garlic involving different varieties, harvesting season and storage life. As a result of these investigations, optimum conditions were established for each crop. The effect of irradiation and storage on sprouting, rottage and weight loss of potatoes is presented. The sprouting initiated in the unirradiated samples after 2 months reaching 51, 80 and 100% on 4, 5 and 6 months storage respectively. Weight losses were observed in the irradiated and unirradiated samples. (A.B.)

  12. Effects of gamma irradiation on the volatile compounds of ginger rhizome (Zingiber officinale Roscoe)

    International Nuclear Information System (INIS)

    Wu, J.J.; Yang, J.S.

    1994-01-01

    Gingers were irradiated at a dose of 0.05 kGy to inhibit sprouting and conserve quality. Effects of gamma irradiation on the flavor compounds of ginger were studied. After 3 months of storage after irradiation, the quantities of some major volatile compounds such as alpha-zingiberene, alpha-bergamotene, neral, geranial, and alpha-curcumene were significantly lower in irradiated than in unirradiated ginger, although no difference was found immediately after irradiation. A triangle test showed no difference between irradiated and unirradiated gingers stored for 1 month at ambient temperature but showed significant difference after 5 months of storage

  13. A simple and rapid in situ preconcentration method for the determination of phosphate in environmental waters by use of solid-phase extraction, and its applications to brackish lake waters.

    Science.gov (United States)

    Okumura, M; Tong, L; Fujinaga, K; Seike, Y

    2001-05-01

    A simple and rapid in situ preconcentration method for the determination of phosphate in environmental waters has been developed for field analysis. This method is based on solid-phase extraction on a zirconium-loaded Sep-Pack Accell CM cartridge (Zr-SP) and is applicable to studies in which sampling is performed by use of a graduated syringe to prevent contamination and to ensure easy operation at sampling sites. The Zr-SP cartridge was prepared by passing 0.1 mol L(-1) zirconium solution through a Sep-Pak Accell CM cartridge, packed with cation exchange sorbent based on a silica matrix. The adsorption of phosphate and its desorption depend only on the pH of the solution. A water sample containing phosphate was adjusted to pH 2 and passed through the Zr-SP cartridge to collect it. The retained phosphate was quantitatively eluted with 0.5 mol L(-1) sodium hydroxide solution. The phosphate retained in the Zr-SP cartridge was stable for at least one month. The established preconcentration method was successfully applied to brackish lake waters to investigate seasonal changes in the distribution and behavior of phosphate in a brackish lake.

  14. Intercomparison campaign of Contracted Partner Institutes 1997

    International Nuclear Information System (INIS)

    Reinen, H.A.J.M.; Tijsmans, M.H.; Van Tuinen, S.T.; Overwater, R.M.W.; Aldenkamp, F.J.

    1998-01-01

    The Dutch National Plan for Nuclear Emergency Planning and Response (EPR) is trained frequently. Intercomparison campaigns and exercises are part of this training for the Contracted Partner Institutes (CPI). The results of an intercomparison campaign in 1997 for the CPI are reported. Two carbon cartridges, one contaminated homogeneously and one inhomogeneously with 131 I, and a water sample contaminated with 134 Cs and 137 Cs were analysed by means of gamma spectroscopy. The results had to be faxed to RIVM within the time limits prescribed in the emergency protocols for CPI, i.e. 2 hours for the cartridges and 24 hours for the water sample. Most CPI reported in time. The results for the inhomogeneously contaminated cartridge are within 25% from the accepted reference value (ARV). For the homogeneously contaminated cartridge the results are within 40% from the ARV. In reality, the contamination of the cartridge will have an exponential profile, with most of the activity in the first few millimeters. In this situation results can be expected to be within 20% from the true value. The results for the water sample are within 5% from the ARV. Although most CPI have applied corrections for coincidence summing for 134 Cs there is still a systematic error of 4% for this nuclide. In regard of the requirements for measurements during emergency situations, the results of this intercomparison campaign are satisfactory

  15. A New Solid Phase Extraction for the Determination of Anthocyanins in Grapes

    Directory of Open Access Journals (Sweden)

    Marta Ferreiro-González

    2014-12-01

    Full Text Available A method for the concentration and cleaning of red grape extracts prior to the determination of anthocyanins by UPLC-DAD has been developed. This method is of special interest in the determination of phenolic maturity as it allows the analysis of the anthocyanins present in grapes. Several different SPE cartridges were assessed, including both C-18- and vinylbenzene-based cartridges. C-18-based cartridges presented a very low retention for the glucosylated anthocyanidins while vinylbenzene-based cartridges showed excellent retention for these compounds. The optimized method involves the initial conditioning of the cartridge using 10 mL of methanol and 10 mL of water, followed by loading of up to 100 mL of red grape extract. Ten mL of water was used in the washing step and anthocyanins were subsequently eluted using 1.5 mL of acidified methanol at pH 2. This method simplifies the determination of individual anthocyanins as, on the one hand, it cleans the sample of interference and, on the other hand, it increases the concentration to up to 25:1.5. The developed method has been validated with a range of different grapes and it has also been tested as a means of determining the different anthocyanins in grapes with different levels of maturity.

  16. Simple system for isothermal DNA amplification coupled to lateral flow detection.

    Directory of Open Access Journals (Sweden)

    Kristina Roskos

    Full Text Available Infectious disease diagnosis in point-of-care settings can be greatly improved through integrated, automated nucleic acid testing devices. We have developed an early prototype for a low-cost system which executes isothermal DNA amplification coupled to nucleic acid lateral flow (NALF detection in a mesofluidic cartridge attached to a portable instrument. Fluid handling inside the cartridge is facilitated through one-way passive valves, flexible pouches, and electrolysis-driven pumps, which promotes a compact and inexpensive instrument design. The closed-system disposable prevents workspace amplicon contamination. The cartridge design is based on standard scalable manufacturing techniques such as injection molding. Nucleic acid amplification occurs in a two-layer pouch that enables efficient heat transfer. We have demonstrated as proof of principle the amplification and detection of Mycobacterium tuberculosis (M.tb genomic DNA in the cartridge, using either Loop Mediated Amplification (LAMP or the Exponential Amplification Reaction (EXPAR, both coupled to NALF detection. We envision that a refined version of this cartridge, including upstream sample preparation coupled to amplification and detection, will enable fully-automated sample-in to answer-out infectious disease diagnosis in primary care settings of low-resource countries with high disease burden.

  17. Use of a new tandem cation/anion exchange system with clinical-scale generators provides high specific volume solutions of technetium-99m and rhenium-188

    International Nuclear Information System (INIS)

    Knapp, F.R. Jr.; Beets, A.L.; Mirzadeh, S.; Guhlke, S.; Univ. of Bonn

    1998-03-01

    In this paper the authors describe the first application of a simple and inexpensive post elution tandem cation-anion exchange column system which is based on generator elution with salts of weak acids such as ammonium acetate instead of saline solution to provide very high specific volume solutions of technetium-99m and rhenium-188 from clinical scale molybdenum-99/technetium-99m generator prepared from low specific activity (n,y) molybdenum-99, and tungsten-188/rhenium-188 generators, respectively. Initial passage of the bolus through a strong cation exchange cartridge converts the ammonium acetate to acetic acid which is essentially not ionized at the acidic pH, allowing specific subsequent amine type (QMA SepPak trademark) anion exchange cartridge column trapping of the microscopic levels of the pertechnetate or perrhenate. Subsequent elution of the anion cartridge with a small volume ( 500 mCi/mL) from the alumina-based tungsten-188/rhenium-188 generator

  18. Autonomous detection of ISO fade point with color laser printers

    Science.gov (United States)

    Yan, Ni; Maggard, Eric; Fothergill, Roberta; Jessome, Renee J.; Allebach, Jan P.

    2015-01-01

    Image quality assessment is a very important field in image processing. Human observation is slow and subjective, it also requires strict environment setup for the psychological test 1. Thus developing algorithms to match desired human experiments is always in need. Many studies have focused on detecting the fading phenomenon after the materials are printed, that is to monitor the persistence of the color ink 2-4. However, fading is also a common artifact produced by printing systems when the cartridges run low. We want to develop an automatic system to monitor cartridge life and report fading defects when they appear. In this paper, we first describe a psychological experiment that studies the human perspective on printed fading pages. Then we propose an algorithm based on Color Space Projection and K-means clustering to predict the visibility of fading defects. At last, we integrate the psychological experiment result with our algorithm to give a machine learning tool that monitors cartridge life.

  19. Development of ballistics identification—from image comparison to topography measurement in surface metrology

    International Nuclear Information System (INIS)

    Song, J; Chu, W; Vorburger, T V; Thompson, R; Renegar, T B; Zheng, A; Yen, J; Silver, R; Ols, M

    2012-01-01

    Fired bullets and ejected cartridge cases have unique ballistics signatures left by the firearm. By analyzing the ballistics signatures, forensic examiners can trace these bullets and cartridge cases to the firearm used in a crime scene. Current automated ballistics identification systems are primarily based on image comparisons using optical microscopy. The correlation accuracy depends on image quality which is largely affected by lighting conditions. Because ballistics signatures are geometrical micro-topographies by nature, direct measurement and correlation of the surface topography is being investigated for ballistics identification. A Two-dimensional and Three-dimensional Topography Measurement and Correlation System was developed at the National Institute of Standards and Technology for certification of Standard Reference Material 2460/2461 bullets and cartridge cases. Based on this system, a prototype system for bullet signature measurement and correlation has been developed for bullet signature identifications, and has demonstrated superior correlation results. (paper)

  20. The Kansas State University revolving sputter source

    International Nuclear Information System (INIS)

    Tipping, T.N.

    1989-01-01

    It has been that the perfect ion source is one which runs in a very stable mode, runs continuously, and has the ability to change ion species without sacrificing the previous two requirements. This paper presents an approximation to the perfect ion source, the KSU Revolving Sputter Source. The source consists of an Aarhus-geometry sputter source with the addition of a rotating wheel which holds eight sputter cathodes. The wheel consists of a front plate with eight fixed Macor insulators and a back plate with eight Macor insulators held in place by the tension of eight springs. The cathode assembly consists of a copper cartridge with a threaded rod on one end and a sputter cathode with a threaded hole on the back. The cathode is screwed onto the cartridge and the whole assembly may be loaded into the wheel. A small spring on the side of the cartridge holds the assembly in the wheel

  1. Recirculating electric air filter for use in confined spaces

    International Nuclear Information System (INIS)

    Bergman, W.; Biermann, A.; Kuhl, W.

    1985-01-01

    We have developed recirculating electric air filters for use in confined spaces where the existing ventilation system is not adequate for removing suspended particles. Two experimental filters were built and evaluated, both of which consisted of a cylindrical cartridge filter fitted over an air blower. In one design the cylindrical cartridge is a disposable unit with the electrodes and filter medium built as an integrated unit. The second design has a cylindrical cartridge that can be easily disassembled to allow replacement of the filter medium. Both designs were evaluated in a 354-ft 3 test cell using NaCl aerosols. The second design was installed and evaluated in a chamber where highly radioactive 238 PuO 2 powder is formed into pellets. We have derived equations that describe the theory of recirculating air filters. The predicted performance compares well with experimental measurements under controlled conditions. 2 refs., 7 figs., 1 tab. (DT)

  2. Electronic Vapor Cigarette Battery Explosion Causing Shotgun-like Superficial Wounds and Contusion

    Directory of Open Access Journals (Sweden)

    Siri Shastry, MD

    2016-03-01

    Full Text Available INTRODUCTION Electronic vapor cigarettes (E-cigarettes were created in 2003 as an alternative to traditional tobacco cigarettes. E-cigarettes have been available in the United States since 2006.1 The typical E-cigarette consists of a cartridge that contains liquid, an atomizer that heats the liquid (i.e. acts as a vaporizer, as well as a battery. The liquid contained within the cartridge contains nicotine, propylene glycol and/ or glycerol as well as flavorings. The consumer uses an E-cigarette through either pushing a button or inhalation, which triggers heating and therefore aerosolizes the liquid within the cartridge, emulating cigarette “smoke.” The newest E-cigarettes are larger than nicotine cigarettes and employ stronger, rechargeable batteries as a power source.2,3

  3. Engineering evaluation of solids/liquids separation processes applicable to sludge treatment project

    International Nuclear Information System (INIS)

    Duncan, J.B.

    1998-01-01

    This engineering study looks at the solids/liquids separation unit operations after the acid dissolution of the K Basin sludge treatment. Unit operations considered were centrifugation, filtration (cartridge, cross flow, and high shear filtration) and gravity settling. The recommended unit operations for the solids/liquids separations are based upon the efficiency, complexity, and off-the-shelf availability and adaptability. The unit operations recommended were a Robatel DPC 900 centrifuge followed by a nuclearized 31WM cartridge filter. The Robatel DPC 900 has been successfully employed in the nuclear industry on a world wide scale. The 31WM cartridge filter has been employed for filtration campaigns in both the government and civilian nuclear arenas

  4. Basic hydrolysis of 1, 3, 4, 6-tetra-O-acetyl-2-[18F] fluoro-D-glucose on solid phase extraction

    International Nuclear Information System (INIS)

    Zhang Jinming; Tian Jiahe; He Yijie; Huan Dingcai; Liu Boli

    2003-01-01

    A new base hydrolysis method are used for 1, 3, 4, 6-tetra-O-acetyl-2-[ 18 F] fluoro-D-glucose on solid phase extraction. The labeled intermediate is trapped on an active C-18 solid phase extraction cartridge, and hydrolyzed in cartridge with 1 mL 2 mol/L NaOH at room temperature. The results show that there are over 99% of the labeled intermediate being turned into 18 F-FDG within 2 min. It is easy to get 18 F-FDG after neutralized with phosphate buffer, purified by C-18 and Alumina cartridge. The basic hydrolysis on solid extraction is a simple method for preparation of 18 F-FDG

  5. Investigation of Filtration Membranes from the Dairy Protein Industry for Residual Fouling Using Infrared Spectroscopy and Chemometrics

    DEFF Research Database (Denmark)

    Jensen, Jannie Krog

    the reversible fouling can be removed/cleaned. The aim of this thesis is to investigate the residual fouling that is deposited on ultrafiltration and microfiltration membranes after usage. The membrane surfaces are investigated using infrared spectroscopy with an attenuated reflectance sampling unit...... and this is thesis work highlights the strengths and weaknesses of using infrared spectroscopy to investigate residual fouling on membranes and in particular the challenges with the infrared penetration depth when layering in the samples occurs. Real size production membrane cartridges at different stages of use...... microfiltration membrane cartridges were investigated with Attenuated- Total-Reflection Fourier-Transform-Infrared (ATR FT-IR) to map the residual fouling on both types of cartridges. The height of the characteristic amide peaks from proteins were used to determine the relative concentrations. The first...

  6. A rapid high-performance liquid-chromatographic method for simultaneously determining the concentrations of TFM and Bayer 73 in water during lampricide treatments

    Science.gov (United States)

    Dawson, V.K.

    1982-01-01

    The high-performance liquid-chromatography (HPLC) procedure requires only minutes per sample, is specific, and is relatively sensitive (limit of detection 18 disposable cartridge. The cartridge adsorbs and retains both the lampricides and the internal standard. The quantitative elution of the three chemicals from the cartridge with a small volume of methanol effectively concentrates the sample and provides sample cleanup. The methanol extract is then analyzed directly by HPLC on an MCH 10 reverse phase column by using a methanol:0.01 mol/L acetate buffer (87:13, v:v) as the mobile phase at 2 mL/min and detected by ultraviolet spectrophotometry at 330 (or 254) nm. A microprocessor data system further facilitates the procedure by quantifying off-scale peaks and yielding results directly in units of concentration (mg/L).

  7. The determination of radiocaesium in sea and fresh waters

    International Nuclear Information System (INIS)

    Baker, C.W.

    1975-10-01

    The caesium is adsorbed on to a cartridge of silica gel impregnated with ammonium molybdophosphate from 50 litres of filtered water, adjusted to pH 2 with nitric acid. The cartridge is then placed in a well crystal detector and gamma counted. An additional separation step is required if zirconium-95/niobium-95 contamination has occurred, as shown by gamma spectrometric analysis of the cartridge. The measurement of caesium-137 and caesium-134 is by conventional γ-spectrometry. The output of the analysing system is ASCII paper tape, and a PDP-8 computer is used to convert this spectral information to activity of caesium-137 and -134 in pCi l -1 at the time of sample collection. (U.K.)

  8. Linear and/or curvilinear rail mount system

    Science.gov (United States)

    Thomas, Jackie D. (Inventor); Harris, Lawanna L. (Inventor)

    2012-01-01

    One or more linear and/or curvilinear mounting rails are coupled to a structure. Each mounting rail defines a channel and at least one cartridge assembly is engaged in the channel. Each cartridge assembly includes a housing that slides within the channel. The housing defines a curvilinearly-shaped recess longitudinally aligned with the channel when the housing is in engagement therewith. The cartridge assembly also includes a cleat fitted in the recess for sliding engagement therealong. The cleat can be coupled to a fastener that passes through the mounting rail and the housing when the housing is so-engaged in the channel. The cleat is positioned in the recess by a position of the fastener.

  9. Apparatus for rendering at least a portion of a device inoperable and related methods

    Energy Technology Data Exchange (ETDEWEB)

    Daniels, Michael A.; Steffler, Eric D.; Hartenstein, Steven D.; Wallace, Ronald S.

    2016-11-08

    Apparatus for rendering at least a portion of a device inoperable may include a containment structure having a first compartment that is configured to receive a device therein and a movable member configured to receive a cartridge having reactant material therein. The movable member is configured to be inserted into the first compartment of the containment structure and to ignite the reactant material within the cartridge. Methods of rendering at least a portion of a device inoperable may include disposing the device into the first compartment of the containment structure, inserting the movable member into the first compartment of the containment structure, igniting the reactant material in the cartridge, and expelling molten metal onto the device.

  10. Pneumatic probe with laser interferometer

    International Nuclear Information System (INIS)

    Wilkens, P.H.

    1978-01-01

    Improvements to upgrade the accuracy of Rotacon probes by a complete redesign of probe to include a Michelson interferometer to replace the existing long-range capacity transducer are described. This has resulted in a compact and interchangeable probe cartridge with a 3 μin. resolution and accuracy; the cartridge can be installed and replaced in the Rotacon gauge with the minimum of realignment, which should reduce our dependence on operator skill. In addition, the stylus contact force can be reduced to 750 mg for the contacting types, but an alternative feature, which we are still developing, will use a gas jet cushion in place of the stylus to provide a noncontacting version of the same basic probe cartridge. This device is very sensitive to external vibration effects because it is virtually frictionless

  11. Prevalence of Ex Vivo High On-treatment Platelet Reactivity on Antiplatelet Therapy after Transient Ischemic Attack or Ischemic Stroke on the PFA-100(®) and VerifyNow(®).

    LENUS (Irish Health Repository)

    Kinsella, Justin A

    2012-09-12

    BACKGROUND: The prevalence of ex vivo high on-treatment platelet reactivity (HTPR) to commonly prescribed antiplatelet regimens after transient ischemic attack (TIA) or ischemic stroke is uncertain. METHODS: Platelet function inhibition was simultaneously assessed with modified light transmission aggregometry (VerifyNow; Accumetrics Inc, San Diego, CA) and with a moderately high shear stress platelet function analyzer (PFA-100; Siemens Medical Solutions USA, Inc, Malvern, PA) in a pilot, cross-sectional study of TIA or ischemic stroke patients. Patients were assessed on aspirin-dipyridamole combination therapy (n = 51) or clopidogrel monotherapy (n = 25). RESULTS: On the VerifyNow, HTPR on aspirin was identified in 4 of 51 patients (8%) on aspirin-dipyridamole combination therapy (≥550 aspirin reaction units on the aspirin cartridge). Eleven of 25 (44%) patients had HTPR on clopidogrel (≥194 P2Y12 reaction units on the P2Y12 cartridge). On the PFA-100, 21 of 51 patients (41%) on aspirin-dipyridamole combination therapy had HTPR on the collagen-epinephrine (C-EPI) cartridge. Twenty-three of 25 patients (92%) on clopidogrel had HTPR on the collagen-adenosine diphosphate (C-ADP) cartridge. The proportion of patients with antiplatelet HTPR was lower on the VerifyNow than PFA-100 in patients on both regimens (P < .001). CONCLUSIONS: The prevalence of ex vivo antiplatelet HTPR after TIA or ischemic stroke is markedly influenced by the method used to assess platelet reactivity. The PFA-100 C-ADP cartridge is not sensitive at detecting the antiplatelet effects of clopidogrel ex vivo. Larger prospective studies with the VerifyNow and with the PFA-100 C-EPI and recently released Innovance PFA P2Y cartridges (Siemens Medical Solutions USA, Inc) in addition to newer tests of platelet function are warranted to assess whether platelet function monitoring predicts clinical outcome in ischemic cerebrovascular disease.

  12. Anesthetic Efficacy of a Combination of 4% Prilocaine/2% Lidocaine with Epinephrine for the Inferior Alveolar Nerve Block: A Prospective, Randomized, Double-blind Study.

    Science.gov (United States)

    Cook, Olivia; Nusstein, John; Drum, Melissa; Fowler, Sara; Reader, Al; Draper, John

    2018-05-01

    Prilocaine plain has a high pH and concentration (4%), which could decrease the pain of injection and increase success. The purpose of this study was to compare pain associated with anesthetic solution deposition and the degree of pulpal anesthesia obtained with the combination of prilocaine and lidocaine versus a lidocaine and lidocaine combination when used for inferior alveolar nerve blocks (IANBs). One hundred eighteen asymptomatic subjects were randomly given a combination of 1 cartridge of 4% prilocaine plain plus 1 cartridge of 2% lidocaine with 1:100,000 epinephrine or a combination of 2 cartridges of 2% lidocaine with 1:100,000 epinephrine for the IANB at 2 separate appointments. Subjects rated the pain associated with anesthetic solution deposition of injection. Mandibular teeth were tested with an electric pulp tester every 4 minutes for 57 minutes. Anesthesia was considered successful when 2 consecutive 80 readings were obtained within 17 minutes and the 80 reading was continuously sustained for 57 minutes. Comparisons for anesthetic success were analyzed using the exact McNemar test, and pain ratings associated with anesthetic solution deposition were analyzed using multiple Wilcoxon matched pairs signed rank tests; both were adjusted using the step-down Bonferroni method of Holm. Four percent prilocaine plain was significantly less painful upon anesthetic solution deposition. Pulpal anesthetic success was not significantly different between the 2 combinations. The combination of 4% prilocaine plain plus 2% lidocaine with 1:100,000 epinephrine did not increase pulpal anesthetic success for IANBs compared with a combination of 2 cartridges of 2% lidocaine with 1:100,000 epinephrine. Pain associated with anesthetic solution deposition from the first cartridge of 4% prilocaine plain was significantly less when compared with the first cartridge of 2% lidocaine with 1:100,000 epinephrine. Copyright © 2018 American Association of Endodontists. Published

  13. Evaluation of the FTA carrier device for human papillomavirus testing in developing countries.

    Science.gov (United States)

    Gonzalez, Paula; Cortes, Bernal; Quint, Wim; Kreimer, Aimée R; Porras, Carolina; Rodríguez, Ana Cecilia; Jimenez, Silvia; Herrero, Rolando; Struijk, Linda; Hildesheim, Allan; Melchers, Willem

    2012-12-01

    Liquid-based methods for the collection, transportation, and storage of cervical cells are cumbersome and expensive and involve laborious DNA extraction. An FTA cartridge is a solid carrier device, easier to handle and allowing simple DNA elution for human papillomavirus (HPV) testing. HPV-DNA results from cervical specimens collected in PreservCyt medium (Hologic, Inc.) and the indicating FTA elute cartridge were compared in an area where transportation and storage may affect the performance of the test. Cervical cells from 319 young adult women enrolled in the Costa Rica Vaccine Trial were collected by a nurse using a Cervex brush (Roberts), which was placed on the FTA cartridge and subsequently rinsed in 20 ml of PreservCyt medium. Two 0.5-ml PreservCyt aliquots were frozen for HPV-PCR testing; the FTA cartridges were kept at room temperature. HPV-DNA detection and typing was performed using SPF(10) PCR/DEIA (DNA enzyme immunoassay detection of amplimers)/LiPA(25) system. The percent agreement, agreement among positives, and kappas were estimated. Positivity was higher for FTA compared to PreservCyt specimens (54.5% versus 45.8%, P FTA collection for HPV testing. HPV-DNA detection from FTA cartridges is broadly comparable to detection from PC medium. The higher HPV detection observed for FTA-collected specimens should be explored further. FTA cartridges could provide a simpler and more cost-effective method for cervical cell collection, storage, and transportation for HPV-DNA detection in research settings in developing countries.

  14. Studio di un algoritmo lineare di ricostruzione analogica della posizione per il rivelatore a pixel di ATLAS

    CERN Document Server

    Arelli-Maffioli, A; Troncon, C; Lari, T

    2007-01-01

    A detailed study of spatial resolution of Atlas pixel sensors prototypes was performed. Charge interpolation was used and allowed for a significant improvement with respect to digital resolution. A simplified algorithm for charge interpolation was developed. Its application to both unirradiated and irradiated sensors is presented and discussed.

  15. Effects of irradiation on the volatile compounds of garlic (Allium sativum L)

    International Nuclear Information System (INIS)

    Wu, J.J.; Yang, J.S.; Liu, M.S.

    1996-01-01

    The effects of 0.15 kGy gamma irradiation on the content of volatile compounds in garlic bulbs during storage at room temperature were evaluated. The content of diallyl disulphide decreased immediately after irradiation. However, at the end of 8-month storage both irradiated and unirradiated samples showed a significant increase in diallyl disulphide

  16. Nonane as a radiolytic product in irradiated bacon

    International Nuclear Information System (INIS)

    Singh, H.; Guerrero, A.; Kremers, W.

    1993-01-01

    Formation of nonane in irradiated bacon has been confirmed by gas chromatographic/mass spectrometric (GC/MS) analysis of irradiated nitrogen-flushed homogenized bacon in scaled glass vials. Unirradiated bacon did not show the presence of nonane under similar conditions

  17. Cladding properties under simulated fuel pin transients

    International Nuclear Information System (INIS)

    Hunter, C.W.; Johnson, G.D.

    1975-01-01

    A description is given of the HEDL fuel pin testing program utilizing a recently developed Fuel Cladding Transient Tester (FCTT) to generate the requisite mechanical property information on irradiated and unirradiated fast reactor fuel cladding under temperature ramp conditions. The test procedure is described, and data are presented

  18. Iodine stress corrosion cracking in Zircaloy

    International Nuclear Information System (INIS)

    Andrade, A.H.P. de; Pelloux, R.M.N.

    1983-01-01

    The subcritical growth of iodine-induced cracks in unirradiated Zircaloy plates is investigated as a function of the stress intensity factor K. The testing variables are: crystallographic texture (f-Number), microstructure (grain directionaly), heat treatment (stress relieved vs recrystallized plate), and temperature. The iodine partial pressure is 40Pa. (author) [pt

  19. A preliminary report on the SRP [Savannah River Plant] source term study

    International Nuclear Information System (INIS)

    Woodley, R.E.; Baldwin, D.L.

    1984-09-01

    The present report describes the experimental system developed for the measurement of fission product release from Savannah River Plant (SRP) fuels and the preliminary measurements performed on unirradiated SRP fuel specimens and simulated irradiated fuel to check out the system prior to its installation in a hot cell for measurements on irradiated SRP fuel

  20. P N Kotru

    Indian Academy of Sciences (India)

    Volume 33 Issue 4 August 2010 pp 377-382 Electrical Properties. Dielectric and thermal studies on gel grown strontium tartrate pentahydrate crystals ... High resolution X-ray diffraction studies on unirradiated and irradiated strontium hexaferrite crystals · Balwinder Kaur Monita Bhat F Licci Ravi Kumar K K Bamzai P N Kotru.

  1. Irradiation of onions on a large scale

    International Nuclear Information System (INIS)

    Kawashima, Koji; Hayashi, Toru; Uozumi, J.; Sugimoto, Toshio; Aoki, Shohei

    1984-01-01

    A large number of onions of var. Kitamiki and Ohotsuku were irradiated in September followed by storage at 0 deg C or 5 deg C. The onions were shifted from cold-storage facilities to room temperature in mid-March or in mid-April in the following year. Their sprouting, rooting, spoilage characteristics and sugar content were observed during storage at room temperature. Most of the unirradiated onions sprouted either outside or inside bulbs during storage at room temperature, and almost all of the irradiated ones showed small buds with browning inside the bulb in mid-April irrespective of the storage temperature. Rooting and/or expansion of bottom were observed in the unirradiated samples. Although the irradiated materials did not have root, they showed expansion of bottom to some extent. Both the irradiated and unirradiated onions spoiled slightly unless they sprouted, and sprouted onions got easily spoiled. There was no difference in the glucose content between the unirradiated and irradiated onions, but the irradiated ones yielded higher sucrose content when stored at room temperature. Irradiation treatment did not have an obvious effect on the quality of freeze-dried onion slices. (author)

  2. Effect of storage time on microbial quality of some spices and dried ...

    African Journals Online (AJOL)

    The effect of storage time on the microbial quality of some spices and dried seasonings (SDS) (dawadawa, pepper, ginger, shrimp and fish powders) was studied over a 12-month period. Microbial load and profile of irradiated and unirradiated SDS were assessed at 0, 6 and 12-month periods. The range of total variable ...

  3. Characterization of blend hydrogels based on plasticized starch/cellulose acetate/carboxymethyl cellulose synthesized by electron beam irradiation

    Science.gov (United States)

    Senna, Magdy M.; Mostafa, Abo El-Khair B.; Mahdy, Sanna R.; El-Naggar, Abdel Wahab M.

    2016-11-01

    Blend hydrogels based on aqueous solutions of plasticized starch and different ratios of cellulose acetate (CA) and carboxymethyl cellulose (CMC) were prepared by electron beam irradiation (EB). The blends before and after EB irradiation were characterized by thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC). The physico-chemical properties of blend hydrogels prepared by electron beam irradiation were improved compared to unirradiated blends.

  4. In vivo UVB irradiation induces clustering of Fas (CD95) on human epidermal cells

    DEFF Research Database (Denmark)

    Bang, Bo; Gniadecki, Robert; Larsen, Jørgen K

    2003-01-01

    a single dose of UVB irradiation. Normal healthy individuals were irradiated with three minimal erythema doses (MED) of UVB on forearm or buttock skin. Suction blisters from unirradiated and irradiated skin were raised, and Fas, FasL, and apoptosis of epidermal cells quantified by flow cytometry...

  5. Renal function changes associated with aging and ionizing radiation

    International Nuclear Information System (INIS)

    Miller, C.W.; Norrdin, R.W.; Sawyer, S.S.; Nealeigh, R.C.

    1978-01-01

    Renal function testing of irradiated and unirradiated beagles at CRHL has been carried out for the past 7 years using a simultaneous estimation of sodium sulfanilate and sodium iodohippurate 131 I clearance. Evidence has been cited that the beagle kidney is markedly sensitive to whole-body ionizing radiation delivered in the perinatal period. The objectives of this continuing study are to determine the nature of the progression of chronic renal disease, its possible association to hypertension, the impact of unilateral nephrectomy upon an already compromised renal parenchyma, and the age-related changes in renal function. Thus far, data seem to indicate the following conclusions: sulfanilate clearance appears to be a sensitive indicator of impending renal failure, exhibiting earlier and more obvious indicators than BUN (blood urea nitrogen) levels; hypertension does not appear to be a factor in radiation-induced renal failure in the adult dogs studied here, since the average arterial blood pressure was as high in normal control dogs as in irradiated dogs suffering from renal failure; unilateral nephrectomy affected unirradiated dogs less than irradiated animals with mild renal insufficiency. The BUN levels returned to prenephrectomy levels in 8 weeks in the unirradiated group, but required up to 1 year in the dogs with renal insufficiency; and an age related decrease inrenal function was observed in a group of unirradiated dogs studied from 0 to 2 through 13 years of age

  6. Positron annihilation and Moessbauer studies of neutron irradiated reactor pressure vessel steels

    International Nuclear Information System (INIS)

    Brauer, G.; Matz, W.; Liszkay, L.; Molnar, B.

    1990-11-01

    Positron annihilation (lifetime, Doppler broadening) and Moessbauer studies on unirradiated, neutron irradiated and neutron irradiated plus annealed reactor pressure vessel steels (Soviet type 15Kh2NMFA) are presented. The role of microstructural properties and the formation of irradiation-induced precipitates is discussed. (orig.) [de

  7. Delayed metamorphosis and recurrence of bacterial infection in irradiated Rana clamitans tadpoles

    International Nuclear Information System (INIS)

    Hart, D.R.

    1982-03-01

    X-ray doses of 5 and 10 Gy (1 Gy/min) given to premetamorphic Green Frog (Rana clamitans) tadpoles delayed their metamorphosis relative to unirradiated controls. Previous pathogenic bacterial infections recurred in irradiated animals prior to metamorphic climax. Limited mortality occurred during metamorphic climax, 80-105 days after irradiation

  8. Pulsed irradiation of enriched UO{sub 2} in the Annular Core Pulse Reactor (ACPR)

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, T R; Lucoff, D M; Reil, K O; Croucher, D W [Sandia Laboratories (United States)

    1974-07-01

    A series of experiments have been conducted in the Annular Core Pulse Reactor (ACPR) to determine the energy deposition and behavior of enriched UO{sub 2} under pulse conditions. In the experiment single unirradiated pellets with enrichments up to 25 percent were pulse heated to melt temperatures. Temperature and fission product inventory measurements were made and compared with neutron transport calculations. (author)

  9. Fracture mechanics behaviour of neutron irradiated Alloy A-286

    International Nuclear Information System (INIS)

    Mills, W.J.; James, L.A.

    The effect of fast-neutron irradiation on the fatigue-crack propagation and fracture toughness behaviour of Alloy A-286 was characterized using fracture mechanics techniques. The fracture toughness was found to decrease continuously with increasing irradiation damage at both 24 deg. C and 427 deg. C. In the unirradiated and low fluence conditions, specimens displayed appreciable plasticity prior to fracture, and equivalent Ksub(Ic) values were determined from Jsub(Ic) fracture toughness results. At high irradiation exposure levels, specimens exhibited a brittle Ksub(Ic) fracture mode. The 427 deg. C fracture toughness fell from 129 MPa√m in the unirradiated condition to 35 MPa√m at an exposure of 16.2 dpa (total fluence of 5.2x10 22 n/cm 2 ). Room temperature fracture toughness values were consistently 40 to 60 percent higher than the 427 deg. C values. Electron fractography revealed that the reduction in fracture resistance was attributed to a fracture mechanism transition from ductile microvoid coalescence to channel fracture. Fatigue-crack propagation tests were conducted at 427 deg. C on specimens irradiated at 2.4 dpa and 16.2 dpa. Crack growth rates at the lower exposure level were comparable to those in unirradiated material, while those at the higher exposure were slightly higher than in unirradiated material. (author)

  10. Ultraviolet irradiation initiates ectopic foot formation in regenerating ...

    Indian Academy of Sciences (India)

    If the head or base piece of a bisected hydra is irradiated and recombined with the unirradiated missing part, regeneration proceeds normally indicating that exposure of a body part with either an intact head or foot to UVC does not influence pattern formation. Most significantly, in the middle piece, but not in the head or the ...

  11. Analysis of gamma irradiated pepper constituents, 5

    International Nuclear Information System (INIS)

    Takagi, Kazuko; Okuyama, Tsuneo; Ishikawa, Toshihiro.

    1988-01-01

    Gamma irradiated peppers (10 krad, 100 krad, 1 Mrad) were analyzed by HPLC. The extraction method and HPLC conditions were same as the first report, that is, the extraction from pepper was performed by Automatic Air Hammer and the extracted samples were separated on a reversed phase C 8 column with a concave gradient from 0.1% trifluoro aceticacid (TFA) in water to 75% acetonitrile-0.1% TFA in water for 60 minutes and detected at 210 nm, 280 nm. It is difficult to compare with irradiated and unirradiated pepper constituents by their peak height or area. And the method of multi variant statistically analysis was introduced. The 'peak n area/peak n + 1 area' ratio was calculated by computer. Each peak area was accounted by integrator. The value of these ratio were called 'parameter'. Each chromatogram has 741 parameters calculated with 39 chromatographic peaks. And these parameters were abopted to the multi variant statiscally analysis. Comparison of constituents between irradiated pepper and unirradiated pepper was done by 741 parameters. The correlation of parameters between irradiated and unirradiated was investigated by use of computer. Some parameters of irradiated case were selected as which had no correlation with unirradiated case. That is to say these parameters were thought to be changed with gamma spectrum irradiation. By this method, Coumarin was identified as a changed component with gamma irradiation. (author)

  12. An assay of the physicochemical characters of radiation sterilized plastic transfusion

    International Nuclear Information System (INIS)

    Liu Keliang

    1988-01-01

    In order to adapt radiation sterilization to the need of clinical use by means of 3 H-TdR incorporation, the physicochemical charaters were studied between irradiated and unirradiated plastic transfusion sets. The results showed that a large radiation dose of 2.5 to 10 x 10 4 Gy had no damage on the plastic transfusion sets, nor toxic to human

  13. Fast neutron induced increase of flowering in portulaca grandiflora linn

    International Nuclear Information System (INIS)

    Abraham, V.; Desai, B.M.

    1975-01-01

    Unbranched cuttings were exposed to fast neutron doses of 71-284 rads and planted along with unirradiated controls. There was a significant increase in the numbers of flowers in the treated populations due to the increased production of primary and secondary branches. (MG) [de

  14. Influence of a sublethal irradiation on the immune response of the mouse against sheep erythrocytes

    International Nuclear Information System (INIS)

    Beaumariage, M.L.; Hiesche, K.; Moeller, E.; Revesz, L.; Haot, J.

    1975-01-01

    In the CBA mice, the immunological response of the spleen cells (RFC and PFC direct and indirect) against the sheep erythrocytes is highly depressed by a 400R dose of X rays. The recovery is not complete at the 30th day after irradiation. The response of the bone marrow cells either irradiated or unirradiated to the antigenic stimulation is very low [fr

  15. SCK-CEN Contribution to the IAEA Round Robin Exercise on WWER-440 RPV Weld Metal Irradiation Embrittlement, annealing and Re-Embrittlement. Second Progress Report

    International Nuclear Information System (INIS)

    Van Walle, E.; Chaouadi, R.; Scibetta, M.; Lucon, E.; Weber, M.

    1999-07-01

    The report gives the actual status of the contribution of the Belgian Nuclear Research Centre SCK-CEN to the IAEA Round Robin Exercise on WWER-440 RPV Weld Material Irradiation, Annealing and Re-Embrittlement. Results from the reference testing of unirradiated material as well as the results of the CHIVAS-7 experiment are discussed

  16. Fast neutron sensitivity of dry and germinating tomato seeds

    NARCIS (Netherlands)

    Contant, R.B.

    1970-01-01

    A study was made of changes in fast neutron effectiveness during the hydration and germination of tomato seeds. The main findings and conclusions are the following,

    Section 3.6

    Samples of unirradiated seeds and their constituent parts (seedcoat+endosperm and embryo) were taken at short

  17. The preliminary studies on parasitization of Trichogramma chilonis on Helicoverpa armigera eggs and eggs from irradiated Helicoverpa armigera moths

    International Nuclear Information System (INIS)

    Wang Endong; Lu Daguang; Liu Xiaohui; Li Yongjun; Zhang Shuyong; Liu Qiongru; Wang Huasong

    2002-01-01

    The parasitization rates of Trichogramma chilonis on 250 Gy irradiated and unirradiated fresh eggs of cotton bollworm, Helicoverpa armigera, were not significantly different. The parasitization rate on irradiated chill-stored eggs of H. armigera was lower than that on irradiated fresh eggs. The parasitization rates on eggs from 250 Gy irradiated H. armigera moths depended on their embryonated rates

  18. Emergency response to a highway accident in Springfield, Massachusetts, on December 16, 1991

    International Nuclear Information System (INIS)

    1992-06-01

    On December 16, 1991, a truck carrying unirradiated (fresh) nuclear fuel was involved in an accident on US Interstate 91, in Springfield, Massachusetts. This report describes the emergency response measures undertaken by local, State, Federal, and private parties. The report also discusses ''lessons learned'' from the response to the accident and suggests areas where improvements might be made

  19. Report on the visit to Saclay related to the VISA-2 Project, 13.XI - 13. XII 1961; Izvestaj o poseti Saclayu u vezi projekta VISA-2, 13.XI - 13. XII 1961

    Energy Technology Data Exchange (ETDEWEB)

    Milasin, N [Institute of Nuclear Sciences Boris Kidric, Vinca, Beograd (Serbia and Montenegro)

    1963-03-15

    This report describes the activities of the Department for construction materials in Saclay visited by the author. This department deals with both irradiated and unirradiated materials, namely Zirconium, stainless steels, Beryllium which are used for fabrication of fuel element claddings and tubes to be used under reactor conditions. Mechanical properties of these materials are performed by applying different experimental techniques.

  20. Studies on storage stability of radurised Indian Mackerel (Rastrelliger Kanagurta)

    International Nuclear Information System (INIS)

    Ghadi, S.V.; Alur, M.D.; Venugopal, V.; Doke, S.N.; Ghosh, S.K.; Lewis, N.F.; Nadkarni, G.B.

    1977-01-01

    The present report describes the storage stability of mackerel maintained at various temperatures (0deg-20degC). The investigations include radiation-induced shifts in microflora of mackerel during storage, and time-temperature-tolerance (TTT) studies with the unirradiated and radurized mackerel. (author)

  1. Application of thermoluminescence measurements to detect irradiated strawberries

    International Nuclear Information System (INIS)

    Heide, L.; Guggenberger, R.; Bogl, K.W.

    1990-01-01

    The thermoluminescence intensity of unirradiated and irradiated strawberries was studied with regard to dose response, storage time, and different varieties. An identification method could finally be developed. Further investigations were carried out to determine the origin of the thermoluminescence effect, which was found to be attributable to mineral grains adhering to the sample surface

  2. Identification of food preserved by ionizing radiation; Preliminary tests in strawberries using thermoluminescent (TL)

    International Nuclear Information System (INIS)

    Rubio, T.; Sillano, O.; Espinoza, J.; Roman, A.; Deza, A.

    1992-01-01

    TL measurements, of irradiated and unirradiated strawberries were carried out, using peel, seeds (achenes), leaves and sediment. The four types of samples presented a different thermoluminescence response. The best results were obtained with sediment removed from the soil of the fruit surface. It is concluded that TL is a promising technique for detecting irradiated strawberries using sediment samples. (author)

  3. Positron lifetime studies of 100-MeV oxygen irradiated Pb-doped Bi-2223 superconductors

    NARCIS (Netherlands)

    Banerjee, T.; Viswanath, R.N.; Kanjilal, D.; Kumar, R.; Ramasamy, S.

    2000-01-01

    Positron lifetime studies have been carried out for unirradiated and 100-MeV oxygen ion irradiated Pb-doped Bi-2223 superconductors. The analysis of positron lifetime spectra revealed three lifetime components: a short lifetime, τ1 = 153–196 ps; an intermediate lifetime, τ2 = 269–339 ps; and a long

  4. Thermal Decompositon Studies Of Pre-Irradiated Nickel (II) Azides ...

    African Journals Online (AJOL)

    The effect of pre-irradiation on the thermal decomposition of three samples of nickel (II) azide was studied. It was found that the rates of thermal decomposition of Ni(OH)N3 increased substantially with increase in pre-irradiation dosage. The initial reaction rates change from time-dependant nucleation law for the unirradiated ...

  5. Review of research on non-destructive analysis of reactor fuel elements

    Energy Technology Data Exchange (ETDEWEB)

    Ruby, S L; Gardner, D G [Westinghouse Electric Corp. (United States). Atomic Power Dept.

    1959-01-01

    This report contains a selected bibliography on the nondestructive assay of irradiated and unirradiated reactor fuel assemblies. The report also includes a discussion and evaluation of these papers in the light of the problems presented by variations in enrichment, alloying, cladding, geometrical arrangement, etc., among the many kinds of fuel assemblies. Suggestions for further development work are made. (author).

  6. Report on the visit to Saclay related to the VISA-2 Project, 13.XI - 13. XII 1961

    International Nuclear Information System (INIS)

    Milasin, N.

    1963-01-01

    This report describes the activities of the Department for construction materials in Saclay visited by the author. This department deals with both irradiated and unirradiated materials, namely Zirconium, stainless steels, Beryllium which are used for fabrication of fuel element claddings and tubes to be used under reactor conditions. Mechanical properties of these materials are performed by applying different experimental techniques

  7. Feasibility of using local tanguile dye as chemical desimeter

    International Nuclear Information System (INIS)

    Cojuangco, J.G.; Juan, N.B.

    1976-05-01

    This is a part of a study on the feasibility of using local materials as radiation dosemeters. The characteristic responses of aqueous tanguile dye with different pH irradiated at various doses of Co-60 are being determined. The effects of different factors light, temperature and pH on the stability of unirradiated dye solutions are also investigated

  8. SCK-CEN Contribution to the''Relation between different measures of exposure-induced shifts in ductile-brittle transition temperatures'' (REFEREE). Progress Report

    International Nuclear Information System (INIS)

    Chaouadi, R.; Van Walle, E.; Fabry, A.; Puzzolante, J.L.

    1998-08-01

    The relationship between Charpy-V (CVN) impact, fracture toughness and tensile properties for selected reactor pressure -vessel steels in the transition temperature range are investigated. Data on the testing of unirradiated material are reported. The applied methods include chemical analysis, Charpy-V impact testing, tensile testing and fracture toughness determination

  9. Expression of the p73 protein in rectal cancers with or without preoperative radiotherapy

    International Nuclear Information System (INIS)

    Pfeifer, Daniella; Gao Jingfang; Adell, Gunnar; Sun Xiaofeng

    2006-01-01

    Purpose: To investigate p73 expression in normal mucosa, primary tumor, and metastasis in relation to radiotherapy (RT) response and clinicopathologic/biologic variables in rectal cancers. Methods and Materials: p73 was immunohistochemically examined on biopsies (unirradiated, n = 102), distant (from the large bowel, n = 82), and adjacent (adjacent to primary tumor, n = 89) normal mucosa samples, primary tumors (n = 131), and lymph node metastasis (n = 32) from rectal cancer patients participating in a clinical trial of preoperative RT. Seventy-four patients received surgery alone and 57 received additional RT. Results: Cytoplasmic p73 was increased in the primary tumor compared with the distant or adjacent mucosa (p ≤ 0.0001). Nuclear (p = 0.02) and cytoplasmic (p = 0.003) p73 was higher in irradiated distant mucosa samples than in unirradiated ones, and nuclear p73 tended to be increased in irradiated primary tumors compared with unirradiated ones (p = 0.06). p73 was positively related to cyclooxygenase-2 expression in irradiated tumors (p = 0.03). p73-negative tumors tended to have a lower local recurrence after RT compared with unirradiated cases (p 0.06). Conclusions: Normal epithelial cells seem more sensitive to RT than tumor cells regarding p73 expression. Patients with p73-negative rectal tumors may have a lower risk of local recurrence after RT

  10. Optical absorption of BaF2 crystals with different prehistory when irradiated by high-energy electrons

    International Nuclear Information System (INIS)

    Chinkov, E P; Stepanov, S A; Shtan'ko, V F; Ivanova, T S

    2016-01-01

    The spectra of stable optical absorption of BaF 2 crystals containing uncontrollable impurities after irradiation with 3 MeV electrons are studied at room temperature. The dependence of the efficiency of stable color accumulation in the region of emerging crossluminescence on the absorption coefficients measured near the fundamental absorption edge in unirradiated crystals of various prehistory is traced. (paper)

  11. An investigation of bystander effects in Schizosaccharomyces pombe

    International Nuclear Information System (INIS)

    DeVeaux, L.C.; Wells, D.P.; Durtschi, L.S.; Reda, M.; Frujinoiu, C.; Harmon, F.

    2003-01-01

    Full text: 'Bystander' effects have been documented in various mammalian cell types and appear to act by two distinct mechanisms. One response requires a functional gap-junction. A non gap-junction-mediated response has also been observed in human cell lines, indicating release of a signaling factor. No analogous response has been investigated in unicellular organisms. Given that DNA damage signaling pathways are present in simple eukaryotes, we investigated bystander signaling effects using a single-celled organism, the fission yeast Schizosaccharomyces pombe. This organism may provide a much simpler model system than higher eukaryotic cells for studying these effects. We measured survival and mutation rate in an unirradiated culture after exposure to an irradiated culture. These two cultures were mixed immediately after irradiation, and any signaling factor that was produced had direct and continuous access to the unirradiated cells during subsequent cell divisions. The irradiated culture was from a multiply auxotrophic strain, whereas the unirradiated culture was from a prototrophic strain. Surviving colonies of the unirradiated culture were thus easily distinguished from those arising from irradiated cells. Mutation rates were measured as forward mutation to 2-deoxyglucose resistance. We have investigated bystander effects with electron and gamma dose from 6 to 20 MeV electron linacs. We varied electron beam energies, dose rates and temporal distributions of dose. The importance of this research stems from the fundamental evolutionary significance of cell signaling of any kind in unicellular systems, representing a major step toward the evolution of multi-cellular states

  12. Detection of irradiation treatment of foods using DNA 'comet assay'

    International Nuclear Information System (INIS)

    Khan, Hasan M.; Delincee, Henry

    1998-01-01

    Microgel electrophoresis of single cells (DNA comet assay) has been investigated to detect irradiation treatment of some food samples. These samples of fresh and frozen rainbow trout, red lentil, gram and sliced almonds were irradiated to 1 or 2 kGy using 10 MeV electron beam from a linear accelerator. Rainbow trout samples yielded good results with samples irradiated to 1 or 2 kGy showing fragmentation of DNA and, therefore, longer comets with no intact cells. Unirradiated samples showed shorter comets with a significant number of intact cells. For rainbow trout stored in a freezer for 11 days the irradiated samples can still be discerned by electrophoresis from unirradiated samples, however, the unirradiated trouts also showed some longer comets besides some intact cells. Radiation treatment of red lentils can also be detected by this method, i.e. no intact cells in 1 or 2 kGy irradiated samples and shorter comets and some intact cells in unirradiated samples. However, the results for gram and sliced almond samples were not satisfactory since some intact DNA cells were observed in irradiated samples as well. Probably, incomplete lysis has led to these deviating results

  13. Detection of irradiation treatment of foods using DNA 'comet assay'

    Energy Technology Data Exchange (ETDEWEB)

    Khan, Hasan M.; Delincee, Henry

    1998-06-01

    Microgel electrophoresis of single cells (DNA comet assay) has been investigated to detect irradiation treatment of some food samples. These samples of fresh and frozen rainbow trout, red lentil, gram and sliced almonds were irradiated to 1 or 2 kGy using 10 MeV electron beam from a linear accelerator. Rainbow trout samples yielded good results with samples irradiated to 1 or 2 kGy showing fragmentation of DNA and, therefore, longer comets with no intact cells. Unirradiated samples showed shorter comets with a significant number of intact cells. For rainbow trout stored in a freezer for 11 days the irradiated samples can still be discerned by electrophoresis from unirradiated samples, however, the unirradiated trouts also showed some longer comets besides some intact cells. Radiation treatment of red lentils can also be detected by this method, i.e. no intact cells in 1 or 2 kGy irradiated samples and shorter comets and some intact cells in unirradiated samples. However, the results for gram and sliced almond samples were not satisfactory since some intact DNA cells were observed in irradiated samples as well. Probably, incomplete lysis has led to these deviating results.

  14. Interlaboratory beta source calibration using TL and OSL on natural quartz

    DEFF Research Database (Denmark)

    Goksu. H.Y.; Bailiff, I.K.; Bøtter-Jensen, L.

    1995-01-01

    Laboratory at GSF using a Go-60 source as well as the in situ measurements with an ionization chamber, calibrated to the primary standards of PTB Braunschweig. Irradiated and unirradiated quartz was distributed to the five laboratories and although different procedures were used for thermoluminescence...

  15. Governance of Cutaneous Photocarcinogenesis by Chronic UVA-Exposed Dermal Fibroblasts

    Science.gov (United States)

    2014-09-01

    2b). In contrast, bystander mela - nocytes cocultured with unirradiated cells led to no appreci- able induction of DCF fluorescence. Experiments were...Life Technologies) containing human mela - nocyte growth supplement (5 ml in 500 ml of media; Life Technolo- gies) and 10% penicillin/streptomycin

  16. Low cycle fatigue behaviour of neutron irradiated copper alloys at 250 and 350 deg. C

    DEFF Research Database (Denmark)

    Singh, B.N.; Stubbins, J.F.; Toft, P.

    2000-01-01

    V) to influence levels of 1.0 - 1.5 x 1024 n/m2 (E> 1 MeV) at 250 and 350 deg. C. These irradiations were carried out in temperature controlled rigs where the irradiation temperature was monitored and controlledcontinuously throughout the whole irradiation experiment. Both unirradiated and irradiated speciments...

  17. Effects of ionizing radiation on differentiation of murine bone marrow cells into mast cells

    International Nuclear Information System (INIS)

    Murakami, Sho; Yoshino, Hironori; Ishikawa, Junya; Yamaguchi, Masaru; Tsujiguchi, Takakiyo; Nishiyama, Ayaka; Yokoyama, Kouki; Kashiwakura, Ikuo

    2015-01-01

    Mast cells, immune effector cells produced from bone marrow cells, play a major role in immunoglobulin E–mediated allergic responses. Ionizing radiation affects the functions of mast cells, which are involved in radiation-induced tissue damage. However, whether ionizing radiation affects the differential induction of mast cells is unknown. Here we investigated whether bone marrow cells of X-irradiated mice differentiated into mast cells. To induce mast cells, bone marrow cells from X-irradiated and unirradiated mice were cultured in the presence of cytokines required for mast cell induction. Although irradiation at 0.5 Gy and 2 Gy decreased the number of bone marrow cells 1 day post-irradiation, the cultured bone marrow cells of X-irradiated and unirradiated mice both expressed mast cell–related cell-surface antigens. However, the percentage of mast cells in the irradiated group was lower than in the unirradiated group. Similar decreases in the percentage of mast cells induced in the presence of X-irradiation were observed 10 days post irradiation, although the number of bone marrow cells in irradiated mice had recovered by this time. Analysis of mast cell function showed that degranulation of mast cells after immunoglobulin E–mediated allergen recognition was significantly higher in the X-irradiated group compared with in the unirradiated group. In conclusion, bone marrow cells of X-irradiated mice differentiated into mast cells, but ionizing radiation affected the differentiation efficiency and function of mast cells. (author)

  18. Nanowire growth from the viewpoint of the thin film polylayer growth theory

    Science.gov (United States)

    Kashchiev, Dimo

    2018-03-01

    The theory of polylayer growth of thin solid films is employed for description of the growth kinetics of single-crystal nanowires. Expressions are derived for the dependences of the height h and radius r of a given nanowire on time t, as well as for the h(r) dependence. These dependences are applicable immediately after the nanowire nucleation on the substrate and thus include the period during which the nucleated nanowire changes its shape from that of cap to that of column. The analysis shows that the nanowire cap-to-column shape transition is continuous and makes it possible to kinetically define the nanowire shape-transition radius by means of the nanowire radial and axial growth rates. The obtained h(t), r(t) and h(r) dependences are found to provide a good description of available experimental data for growth of self-nucleated GaN nanowires by the vapor-solid mechanism.

  19. Growth of yttrium iron garnet single crystals in Na2O-B2O3 flux system in air

    International Nuclear Information System (INIS)

    Bandyopadhyay, Tarun; Saha, Prasenjit

    1977-01-01

    Detailed studies of growth of yttrium iron garnet (YIG) in the flux system Na 2 O-B 2 O 3 were made to delineate the phase stability regions of YIG and the neighbouring crystalline phases, and a tentative working diagram of Na 2 O-B 2 O 3 -YIG in air was drawn from the results of small batch crystal growth runs and solubility studies. The occurrence of a rather narrow field of YIG crystallization in this system was explained on the basis of relative solubilities of different oxides constituting YIG. Several long-time growth runs with some typical compositions were carried out in this system to evaluate its suitability for bulk growth of YIG crystals. The system, although possessing some inherent advantages, was found to suffer from limitations because the maximum size of the self-nucleated crystals grown hardly exceeded 2.00 mm. (author)

  20. Water Purification

    Science.gov (United States)

    1994-01-01

    The Vision Catalyst Purifier employs the basic technology developed by NASA to purify water aboard the Apollo spacecraft. However, it also uses an "erosion" technique. The purifier kills bacteria, viruses, and algae by "catalytic corrosion." A cartridge contains a silver-impregnated alumina bed with a large surface area. The catalyst bed converts oxygen in a pool of water to its most oxidative state, killing over 99 percent of the bacteria within five seconds. The cartridge also releases into the pool low levels of ionic silver and copper through a controlled process of erosion. Because the water becomes electrochemically active, no electricity is required.

  1. Remote filter handling machine for Sizewell B

    International Nuclear Information System (INIS)

    Barker, D.

    1993-01-01

    Two Filter Handling machines (FHM) have been supplied to Nuclear Electric plc for use at Sizewell B Power Station. These machines have been designed and built following ALARP principles with the functional objective being to remove radioactive filter cartridges from a filter housing and replace them with clean filter cartridges. Operation of the machine is achieved by the prompt of each distinct task via an industrial computer or the prompt of a full cycle using the automatic mode. The design of the machine features many aspects demonstrating ALARP while keeping the machine simple, robust and easy to maintain. (author)

  2. Miniature acoustic wave lysis system and uses thereof

    Science.gov (United States)

    Branch, Darren W.; Vreeland, Erika Cooley; Smith, Gennifer Tanabe

    2016-12-06

    The present invention relates to an acoustic lysis system including a disposable cartridge that can be reversibly coupled to a platform having a small, high-frequency piezoelectric transducer array. In particular, the system releases viable DNA, RNA, and proteins from human or bacterial cells, without chemicals or additional processing, to enable high-speed sample preparation for clinical point-of-care medical diagnostics and use with nano/microfluidic cartridges. Also described herein are methods of making and using the system of the invention.

  3. Identification of atractyloside by LC-ESI-MS in alleged herbal poisoning

    CSIR Research Space (South Africa)

    Steenkamp, PA

    2006-11-01

    Full Text Available , approximately 3000 species are used as medicines, and of these, some 350 species are commonly used and traded medicinal plants [3,11]. One of these more commonly used plants is Callilepis laureola DC. (Asteraceae), also called ??Ox-eye daisy?? or ??Wildemagriet... by hand and drawn through the cartridges at approximately 1 ml/min by applying a mild vacuum. The cartridges were washed with 3 ml extracting buffer and dried under vacuum for 10 min. They were then eluted with 3 ml methanol, 3 ml acidic methanol (10 ml...

  4. An in-line clean system for the solid-phase extraction of emerging contaminants in natural waters

    OpenAIRE

    Sodré, Fernando F.; Locatelli, Marco Antonio F.; Jardim, Wilson F.

    2010-01-01

    A solid-phase in-line extraction system for water samples containing low levels of emerging contaminants is described. The system was specially developed for large volume samples (up to 4 L) using commercial solid-phase extraction (SPE) cartridges. Four sets containing PTFE-made connectors, brass adapters and ball valves were used to fit SPE cartridges and sample bottles to a 4-port manifold attached to a 20 L carboy. A lab-made vacuum device was connected to the manifold cap. The apparatus i...

  5. Sistema limpo em linha para extração em fase sólida de contaminantes emergentes em águas naturais An in-line clean system for the solid-phase extraction of emerging contaminants in natural waters

    Directory of Open Access Journals (Sweden)

    Fernando F. Sodré

    2010-01-01

    Full Text Available A solid-phase in-line extraction system for water samples containing low levels of emerging contaminants is described. The system was specially developed for large volume samples (up to 4 L using commercial solid-phase extraction (SPE cartridges. Four sets containing PTFE-made connectors, brass adapters and ball valves were used to fit SPE cartridges and sample bottles to a 4-port manifold attached to a 20 L carboy. A lab-made vacuum device was connected to the manifold cap. The apparatus is robust and less expensive than the typical available system. Its also provides less experimental handling, avoiding cross contamination and sample losses.

  6. Determination of carbonyl compounds in air by HPLC

    International Nuclear Information System (INIS)

    Garcia, S.; Perez, R.M.; Campos, A.; Gonzalez, D.

    1995-09-01

    A method for the determination of seven carbonyl compounds in air is presented. The procedure involve sampling of air by a Sep-Pak cartridge impregnated with 2,4-dinitrophenylhydrazine. Elution was done with 3 mL of acetonitrile and the eluate was diluted to 5 mL. The analysis was done by HPLC with UV detection and external standard method quantification. It has been achieved relative standard deviations about 5% and detection limits of 80 ng/cartridge for formaldehyde, acetaldehyde and acetone+acrolein. Three different types of samples (rural, urban, petrol emission) were successfully analyzed

  7. Determination of carbonyl compounds in air by HPLC

    International Nuclear Information System (INIS)

    Garcia, S.; Perez, R.M.; Campos, A.; Gonzalez, D.

    1995-01-01

    A method for the determination of seven carbonyl compounds in air is presented. The procedure involve sampling of air by a Sep-Pak Cartridge impregnated with 2,4-dinitrophenylhydrazine. Elution was done with 3 mL of acetonitrile and the eluate was diluted to 5 mL. The analysis was done by HPLC with UV detection and external standard method quantification. It has been achieved relative standard deviations about 5% and detection limits of 80 ng/cartridge for formaldehyde, acetaldehyde and acetoacetonitrile. Three different types of samples (rural, urban, petrol emission) were successfully analyzed. (Author) 12 refs

  8. Processamento de cartuchos de impressoras de jato de tinta: um exemplo de gestão de produto pós-consumo

    Directory of Open Access Journals (Sweden)

    Felipe Pereira de Moura

    2012-01-01

    Full Text Available This work presents a route for processing spent ink-jet cartridges in an experimental course. The disassembly of the cartridges requires several steps and the recognition of their different components is essential to define the best final destination (recycling, co-processing. The plastic strips were chemically processed so as to recover gold and copper. The students recognized the difficulty of processing multicomponent wastes and the importance of the chemical work under the best safety conditions; they also experienced many laboratory techniques and recognized the value of the selective collection and the reverse logistics to reach a viable commercial scale recycling.

  9. Determination of carbonyl compounds in air by HPLC; Determinacion de compuestos carbonilicos en aire por HPLC

    Energy Technology Data Exchange (ETDEWEB)

    Garcia, S; Perez, R M; Campos, A; Gonzalez, D

    1995-07-01

    A method for the determination of seven carbonyl compounds in air is presented. The procedure involve sampling of air by a Sep-Pak Cartridge impregnated with 2,4-dinitrophenylhydrazine. Elution was done with 3 mL of acetonitrile and the eluate was diluted to 5 mL. The analysis was done by HPLC with UV detection and external standard method quantification. It has been achieved relative standard deviations about 5% and detection limits of 80 ng/cartridge for formaldehyde, acetaldehyde and acetoacetonitrile. Three different types of samples (rural, urban, petrol emission) were successfully analyzed. (Author) 12 refs.

  10. Deformations of fuel elements under irradiation (Examination of the 2000 C set, investigation of the Cottrell effect)

    International Nuclear Information System (INIS)

    Thome, P.; Allain, C.

    1959-04-01

    The authors report visual and radiographic examinations of cartridges of the 2000 C solution C in order to study the influence of the combustion rate on deformations of these cartridges which spent about a year in an atomic pile. The deformation measurements are interpreted in terms of creep phenomena (Cottrell effect), of surface condition, and buckling. The authors discuss the validity of mechanical tests, the distinction between creep and flow, the deformation of fuel assemblies, the validity of thermal cycle tests, the effects of alloy compositions

  11. New techniques for improved performance in surface blasting operation and optimisation of blast design parameters

    Energy Technology Data Exchange (ETDEWEB)

    Roy, P.P. [Central Mining Research Institute, Dhanbad (India). Blasting Dept.

    1999-02-01

    Experimental blasts were conducted for optimisation of blasting parameters using separate technologies involving non-electric initiation systems, air decking accessories in conjunction with different explosive products like emulsion (cartridge and site-mixed), slurries (cartridge and site-mixed) and ANFO. The cost associated with each such technology was then compared with the conventional methods of drilling and blasting operations. The results of cost analyses are given. Theoretical and practical aspects of such technologies and their best possible usage in order to establish the desired fragmentation, muck profile, wall control and ultimately the accepted level of costs are mentioned in subsequent sections. 16 refs., 17 figs., 8 plates, 11 tabs.

  12. Shale treatment

    Energy Technology Data Exchange (ETDEWEB)

    1941-03-03

    The charge of shale, coal, or the like, is placed in a cartridge which is inserted in a metal cylinder gas and/or steam heated to a temperature of between 300 to 500/sup 0/C is admitted through pipe and passes through two perforations through the charge which is held at a pressure of about .1 to 2 pounds per square inch and an out pipe together with evolved gases and vapours. A lid is clamped in position over the cartridge by means of an eye bolt and a nut.

  13. Novel nanoporous sorbent for solid-phase extraction in petroleum fingerprinting

    Science.gov (United States)

    Alayande, S. Oluwagbemiga; Hlengilizwe, Nyoni; Dare, E. Olugbenga; Msagati, Titus A. M.; Akinlabi, A. Kehinde; Aiyedun, P. O.

    2016-04-01

    Sample preparation is crucial in the analysis of petroleum and its derivatives. In this study, developing affordable sorbent for petroleum fingerprinting analysis using polymer waste such expanded polystyrene was explored. The potential of electrospun expanded polystyrene (EPS) as a sorbent for the solid-phase extraction (SPE) technique was investigated, and its efficiency was compared with commercial cartridges such as alumina, silica and alumina/silica hybrid commercial for petroleum fingerprinting analysis. The chromatograms showed that the packed electrospun EPS fibre demonstrated excellent properties for SPE applications relative to the hybrid cartridges.

  14. Radioimmunoassay in microtiter plates

    International Nuclear Information System (INIS)

    Hirschberg, T.; Hirschberg, H.

    1987-01-01

    A radioimmunoassay was performed in the wells of casein-coated microplates employing 125 I-labelled sheep anti-human second antibody. The antigen-antibody complexes were thereafter dislodged from the well walls using detergent sodium dodecyl sulfate (SDS) and the entire contents of the wells were simultaneously absorbed into 48 cellulose acetate-absorbing cartridges. All 48 cartridges were transferred to counting vials and the radioactivity determined by standard gamma counting techniques. The particular advantage of the method described here is the ease with which the supernatants can be collected and transferred to counting vials with minimal handling of radioactive samples. 6 refs.; 1 figure; 1 table

  15. Bottom loaded filter for radioactive liquids

    International Nuclear Information System (INIS)

    Wendland, W.G.

    1983-01-01

    This invention relates to equipment for filtering liquids and more particularly to filter assemblies for use with radioactive by-products of nuclear power plants. The invention provides a compact, bottom-loaded filter assembly that can be quickly and safely loaded and unloaded without the use of complex remote equipment. The assembly is integrally shielded and does not require external shielding. The closure hatch may be automatically aligned to facilitate quick sealing attachment after replacement of the filter cartridge, and the filter cartridge may be automatically positioned within the filter housing during the replacement operation

  16. Sistema limpo em linha para extração em fase sólida de contaminantes emergentes em águas naturais

    OpenAIRE

    Sodré,Fernando F.; Locatelli,Marco Antonio F.; Jardim,Wilson F.

    2010-01-01

    A solid-phase in-line extraction system for water samples containing low levels of emerging contaminants is described. The system was specially developed for large volume samples (up to 4 L) using commercial solid-phase extraction (SPE) cartridges. Four sets containing PTFE-made connectors, brass adapters and ball valves were used to fit SPE cartridges and sample bottles to a 4-port manifold attached to a 20 L carboy. A lab-made vacuum device was connected to the manifold cap. The apparatus i...

  17. Protection for work on channel W.19.E of the pile G.2

    International Nuclear Information System (INIS)

    Rodier, J.; Chassany, J.Ph.

    1961-01-01

    The cartridges stuck in one of the channels, resulting from a canning burst and attempts at unloading, were removed from the front. Contamination was kept under control by the use of vinyl protective equipment, the working areas being defined and corresponding clothing worn. Constant supervision of the irradiation due to scraps and to the cartridges kept the doses absorbed down to a negligible level. As a result of this very strict discipline on the question of radioactive hygiene there was no spread of contamination nor any irradiation accident in the course of this work, which lasted about a month and involved 3,335 trips to the area. (author) [fr

  18. TL glow ratios at different temperature intervals of integration in thermoluminescence method. Comparison of Japanese standard (MHLW notified) method with CEN standard methods

    International Nuclear Information System (INIS)

    Todoriki, Setsuko; Saito, Kimie; Tsujimoto, Yuka

    2008-01-01

    The effect of the integration temperature intervals of TL intensities on the TL glow ratio was examined in comparison of the notified method of the Ministry of Health, Labour and Welfare (MHLW method) with EN1788. Two kinds of un-irradiated geological standard rock and three kinds of spices (black pepper, turmeric, and oregano) irradiated at 0.3 kGy or 1.0 kGy were subjected to TL analysis. Although the TL glow ratio exceeded 0.1 in the andesite according to the calculation of the MHLW notified method (integration interval; 70-490degC), the maximum of the first glow were observed at 300degC or more, attributed the influence of the natural radioactivity and distinguished from food irradiation. When the integration interval was set to 166-227degC according to EN1788, the TL glow ratios became remarkably smaller than 0.1, and the evaluation of the un-irradiated sample became more clear. For spices, the TL glow ratios by the MHLW notified method fell below 0.1 in un-irradiated samples and exceeded 0.1 in irradiated ones. Moreover, Glow1 maximum temperatures of the irradiated samples were observed at the range of 168-196degC, and those of un-irradiated samples were 258degC or more. Therefore, all samples were correctly judged by the criteria of the MHLW method. However, based on the temperature range of integration defined by EN1788, the TL glow ratio of un-irradiated samples remarkably became small compared with that of the MHLW method, and the discrimination of the irradiated sample from non-irradiation sample became clearer. (author)

  19. Study of Irradiation Effects on the Fracture Properties of A533-Series Ferritic Steels

    International Nuclear Information System (INIS)

    Lee, Yong Bok; Lee, Gyeong Geun; Kwon, Jun Hyun

    2011-01-01

    Since the Kori nuclear power plant unit 3 (Kori-3) was founded in 1986, the surveillance tests have been conducted five times. One of the primary objectives of the surveillance test is to determine the effects of irradiation on reactor pressure vessel (RPV) steel embrittlement. The RPV is made out of ferritic steels such as SA533 type B class 1, which were used for early nuclear power plants industry including Kori-2, 3, 4 and Yonggwang-1, 2 units in Korea. The Westinghouse supplied Kori-3 with the RPV steels ASTM A533 grade B class 1, which is equivalent to SA533 type B class 1. The irradiation effects on tensile properties in ASTM A533 grade B class 1 steel had been studied by Steichen and Williams. They experimentally determined the effect of strain rate and temperature on the tensile properties of unirradiated and irradiated A533 grade B steel 1. The effects of neutron irradiation on ferritic steels could be determined from tensile properties, as well as the fracture strength and toughness measurements. Hunter and Williams have reported that the strength and ductility for unirradiated material at a low strain rate increase with decreasing test temperature. Also, neutron irradiation increases strength and decreases ductility. Crosley and Ripling revealed that the yield strength of unirradiated material rapidly increases with the strain rate. Therefore, yield strength for unirradiated and irradiated materials should be determined by test parameters along with strain rate and temperature. In this study we compare ASTM A533 grad B class 1 steel obtained from several papers with SA533 type B class 1 steel taken from the surveillance data of Kori-3 unit, whose mechanical property of unirradiated and irradiated materials was correlated with the rate-temperature parameter

  20. Evaluation of the limulus amoebocyte lysate test in conjunction with a gram negative bacterial plate count for detecting irradiation of chicken

    Science.gov (United States)

    Scotter, Susan L.; Wood, Roger; McWeeny, David J.

    A study to evaluate the potential of the Limulus amoebocyte lysate (LAL) test in conjuction with a Gram negative bacteria (GNB) plate count for detecting the irradiation of chicken is described. Preliminary studies demonstrated that chickens irradiated at an absorbed dose of 2.5 kGy could be differentiated from unirradiated birds by measuring levels of endotoxin and of numbers of GNB on chicken skin. Irradiated birds were found to have endotoxin levels similar to those found in unirradiated birds but significantly lower numbers of GNB. In a limited study the test was found to be applicable to birds from different processors. The effect of temperature abuse on the microbiological profile, and thus the efficacy of the test, was also investigated. After temperature abuse, the irradiated birds were identifiable at worst up to 3 days after irradiation treatment at the 2.5 kGy level and at best some 13 days after irradiation. Temperature abuse at 15°C resulted in rapid recovery of surviving micro-organisms which made differentiation of irradiated and unirradiated birds using this test unreliable. The microbiological quality of the bird prior to irradiation treatment also affected the test as large numbers of GNB present on the bird prior to irradiation treatment resulted in larger numbers of survivors. In addition, monitoring the developing flora after irradiation treatment and during subsequent chilled storage also aided differentiation of irradiated and unirradiated birds. Large numbers of yeasts and Gram positive cocci were isolated from irradiated carcasses whereas Gram negative oxidative rods were the predominant spoilage flora on unirradiated birds.