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Sample records for unirradiated cartridges self-nucleate

  1. Pulse joining cartridges

    Energy Technology Data Exchange (ETDEWEB)

    Golovashchenko, Sergey Fedorovich; Bonnen, John Joseph Francis

    2016-08-23

    A pulsed joining tool includes a tool body that defines a cavity that receives an inner tubular member and an outer tubular member and a pulse joining cartridge. The tubular members are nested together with the cartridge being disposed around the outer tubular member. The cartridge includes a conductor, such as a wire or foil, that extends around the outer tubular member and is insulated to separate a supply segment from a return segment. A source of stored electrical energy is discharged through the conductor to join the tubular members with an electromagnetic force pulse.

  2. IBM 3480 tape cartridge

    CERN Multimedia

    1984-01-01

    The 3480 tape format is a magnetic tape data storage format developed by IBM. The cartridge contains a single reel. IBM’s 3480 cartridge tape system sought to replace the traditional reels of magnetic tape in the computer center. Because of their speed, reliability, durability and low media cost, these tapes and tape drives are still in high demand. A hallmark of the genre is transferability. Tapes recorded with one tape drive are generally readable on another drive, even if the tape drives were built by different manufacturers.

  3. Loss tangent measurements on unirradiated alumina

    Energy Technology Data Exchange (ETDEWEB)

    Zinkle, S.J.; Goulding, R.H. [Oak Ridge National Lab., TN (United States)

    1996-04-01

    Unirradiated room temperature loss tangent for sapphire and several commercial grades of polycrystalline alumina are complied for frequencies between 10{sup 5} and 4x10{sup 11} Hz. Sapphire exhibits significantly lower values for the loss tangent at frequencies up to 10{sup 11} Hz. The loss tangents of 3 different grades of Wesgo alumina (AL300, AL995, AL998) and 2 different grades of Coors alumina (AD94, AD995) have typical values near {approx}10{sup -4} at a frequency of 10{sup 8} Hz. On the other hand, the loss tangent of Vitox alumina exhibits a large loss peak tan d{approx} 5x10{sup -3} at this frequency.

  4. Combustible Cartridge Case Characterization

    Science.gov (United States)

    1984-02-01

    University (NYU) has resulted in the selection of two cross-linked melamine / formaldehyde acrylic styrene resin systems that can be used in the beater additive... melamine resin Akaradit II stabilizer 20. ABSTRACT (con) Test coupons of combustible cartridge case material were fabricated using these recommended...and agitated for 30 min before the pH was slowly lowered to 3 with p-toluene sulfonic acid. In order to maintain this pH in the felting tank, it was

  5. The Imation 9840 Tape Cartridge

    CERN Multimedia

    It’s a 20 GB uncompressed center-load cartridge used in StorageTek T9840 tape drives. The tape is a Metal Particle (MP) tape suitable for use on all Oracle/Sun/StorageTek 9840 A, B, C and D drives. The 9840 tape has an archival life of 15-30 years.

  6. Rescue Effects: Irradiated Cells Helped by Unirradiated Bystander Cells

    Science.gov (United States)

    Lam, R. K. K.; Fung, Y. K.; Han, W.; Yu, K. N.

    2015-01-01

    The rescue effect describes the phenomenon where irradiated cells or organisms derive benefits from the feedback signals sent from the bystander unirradiated cells or organisms. An example of the benefit is the mitigation of radiation-induced DNA damages in the irradiated cells. The rescue effect can compromise the efficacy of radioimmunotherapy (RIT) (and actually all radiotherapy). In this paper, the discovery and subsequent confirmation studies on the rescue effect were reviewed. The mechanisms and the chemical messengers responsible for the rescue effect studied to date were summarized. The rescue effect between irradiated and bystander unirradiated zebrafish embryos in vivo sharing the same medium was also described. In the discussion section, the mechanism proposed for the rescue effect involving activation of the nuclear factor κB (NF-κB) pathway was scrutinized. This mechanism could explain the promotion of cellular survival and correct repair of DNA damage, dependence on cyclic adenosine monophosphate (cAMP) and modulation of intracellular reactive oxygen species (ROS) level in irradiated cells. Exploitation of the NF-κB pathway to improve the effectiveness of RIT was proposed. Finally, the possibility of using zebrafish embryos as the model to study the efficacy of RIT in treating solid tumors was also discussed. PMID:25625514

  7. ALMA Band 5 Cartridge Performance

    Science.gov (United States)

    Billade, Bhushan; Lapkin, I.; Nystrom, O.; Sundin, E.; Fredrixon, M.; Finger, R.; Rashid, H.; Desmaris, V.; Meledin, D.; Pavolotsky, A.; Belitsky, Victor

    2010-03-01

    Work presented here concerns the design and performance of the ALMA Band 5 cold cartridge, one of the 10 frequency channels of ALMA project, a radio interferometer under construction at Atacama Desert in Chile. The Band 5 cartridge is a dual polarization receiver with the polarization separation performed by orthomode transducer (OMT). For each polarization, Band 5 receiver employs sideband rejection (2SB) scheme based on quadrature layout, with SIS mixers covering 163-211 GHz with 4-8 GHz IF. The LO injection circuitry is integrated with mixer chip and is implemented on the same substrate, resulting in a compact 2SB assembly. Amongst the other ALMA bands, the ALMA Band 5 being the lowest frequency band that uses all cold optics, has the largest mirror. Consequently, ALMA Band 5 mirror along with its support structure leaves very little room for placing OMT, mixers and IF subsystems. The constraints put by the size of cold optics and limited cartridge space, required of us to revise the original 2SB design and adopt a design where all the components like OMT, mixer, IF hybrid, isolators and IF amplifier are directly connected to each other without using any co-ax cables in-between. The IF subsystem uses the space between 4 K and 15 K stage of the cartridge and is thermally connected to 4 K stage. Avoiding co-ax cabling required use of custom designed IF hybrid, furthermore, due to limited cooling capacity at 4 K stage, resistive bias circuitry for the mixers is moved to 15 K stage and the IF hybrid along with an integrated bias-T is implemented using superconducting micro-strip lines. The E-probes for both LO and RF waveguide-to-microstrip transitions are placed perpendicular to the wave direction (back-piece configuration). The RF choke at the end of the probes provides a virtual ground for the RF/LO signal, and the choke is DC grounded to the chassis. The on-chip LO injection is done using a microstrip line directional coupler with slot-line branches in the

  8. Fatigue behavior of unirradiated V-5Cr-5Ti

    Energy Technology Data Exchange (ETDEWEB)

    Gieseke, B.G.; Stevens, C.O.; Grossbeck, M.L. [Oak Ridge National Lab., TN (United States)

    1995-04-01

    The objective of this research is to determine the low cycle fatigue behavior of V-5Cr-5Ti alloys for a range of temperatures and the extent of environmental effects at ambient temperatures. The results of in-vacuum low cycle fatigue tests are presented for unirradiated V-5Cr-5Ti tested at room temperature, 240, and 400{degree}C. A comparison of the fatigue data generated in rough and high vacuums shows that a pronounced environmental degradation of the fatiuge properties exists in this alloy at room temperature. Fatigue life was reduced by as much as 84%. Cyclic stress range data and SEM observations suggest that this reduction is due to a combination of increases in rates of crack initiation and subsequent growth. The relative contribution of each difference is dependent upon the strain range.

  9. StorageTek T10000 Data Cartridge

    CERN Multimedia

    This data cartridge works on several StorageTek systems. The goal is to provide cartridge compatibility across several system. It has been designed for space saving and ultra-high capacity tape. It permit to fulfill high-volume backup, archiving, and disaster recovery.

  10. Optimization of Hydride Rim Formation in Unirradiated Zr 4 Cladding

    Energy Technology Data Exchange (ETDEWEB)

    Shimskey, Rick W.; Hanson, Brady D.; MacFarlan, Paul J.

    2013-09-30

    The purpose of this work is to build on the results reported in the M2 milestone M2FT 13PN0805051, document number FCRD-USED-2013-000151 (Hanson, 2013). In that work, it was demonstrated that unirradiated samples of zircaloy-4 cladding could be pre-hydrided at temperatures below 400°C in pure hydrogen gas and that the growth of hydrides on the surface could be controlled by changing the surface condition of the samples and form a desired hydride rim on the outside diameter of the cladding. The work performed at Pacific Northwest National Laboratory since the issuing of the M2 milestone has focused its efforts to optimize the formation of a hydride rim on available zircaloy-4 cladding samples by controlling temperature variation and gas flow control during pre-hydriding treatments. Surface conditioning of the outside surface was also examined as a variable. The results of test indicate that much of the variability in the hydride thickness is due to temperature variation occurring in the furnaces as well as how hydrogen gas flows across the sample surface. Efforts to examine other alloys, gas concentrations, and different surface conditioning plan to be pursed in the next FY as more cladding samples become available

  11. 42 CFR 84.190 - Chemical cartridge respirators: description.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Chemical cartridge respirators: description. 84.190... Cartridge Respirators § 84.190 Chemical cartridge respirators: description. (a) Chemical cartridge respirators including all completely assembled respirators which are designed for use as...

  12. 42 CFR 84.191 - Chemical cartridge respirators; required components.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Chemical cartridge respirators; required components... Chemical Cartridge Respirators § 84.191 Chemical cartridge respirators; required components. (a) Each chemical cartridge respirator described in § 84.190 shall, where its design requires, contain the...

  13. StorageTek T10000 Tape Cartridge

    CERN Multimedia

    1985-01-01

    Oracle StorageTek T10000T2 cartridge has total capacity of 5 TB. It is actually manufactured by Fuji Film, uses Barium Ferrite (BaFe) particles technology data store, but is also equipped with RFID chip. There is over 1 km of tape inside of the cartridge with 3584 data tracks and it supports over 25000 load/unload cycles. The archival life is estimated to be around 30 years and uncorrected bit error rate is 10-19. CERN however usually migrates data to newer technologies roughly every 5 years in order to keep the footprint under control.

  14. Disposable cartridge biosensor platform for portable diagnostics

    Science.gov (United States)

    Yaras, Yusuf S.; Cakmak, Onur; Gunduz, Ali B.; Saglam, Gokhan; Olcer, Selim; Mostafazadeh, Aref; Baris, Ibrahim; Civitci, Fehmi; Yaralioglu, Goksen G.; Urey, Hakan

    2017-03-01

    We developed two types of cantilever-based biosensors for portable diagnostics applications. One sensor is based on MEMS cantilever chip mounted in a microfluidic channel and the other sensor is based on a movable optical fiber placed across a microfluidic channel. Both types of sensors were aimed at direct mechanical measurement of coagulation time in a disposable cartridge using plasma or whole blood samples. There are several similarities and also some important differences between the MEMS based and the optical fiber based solutions. The aim of this paper is to provide a comparison between the two solutions and the results. For both types of sensors, actuation of the cantilever or the moving fiber is achieved using an electro coil and the readout is optical. Since both the actuation and sensing are remote, no electrical connections are required for the cartridge. Therefore it is possible to build low cost disposable cartridges. The reader unit for the cartridge contains light sources, photodetectors, the electro coil, a heater, analog electronics, and a microprocessor. The reader unit has different optical interfaces for the cartridges that have MEMS cantilevers and moving fibers. MEMS based platform has better sensitivity but optomechanical alignment is a challenge and measurements with whole blood were not possible due to high scattering of light by the red blood cells. Fiber sensor based platform has relaxed optomechanical tolerances, ease of manufacturing, and it allows measurements in whole blood. Both sensors were tested using control plasma samples for activated-Partial-Thromboplastin-Time (aPTT) measurements. Control plasma test results matched with the manufacturer's datasheet. Optical fiber based system was tested for aPTT tests with human whole blood samples and the proposed platform provided repeatable test results making the system method of choice for portable diagnostics.

  15. a Study of Stress Relaxation Rate in Un-Irradiated and Neutron-Irradiated Stainless Steel

    Science.gov (United States)

    Ghauri, I. M.; Afzal, Naveed; Zyrek, N. A.

    Stress relaxation rate in un-irradiated and neutron-irradiated 303 stainless steel was investigated at room temperature. The specimens were exposed to 100 mC, Ra-Be neutron source of continuous energy 2-12 MeV for a period ranging from 4 to 16 days. The tensile deformation of the specimens was carried out using a Universal Testing Machine at 300 K. During the deformation, straining was frequently interrupted by arresting the cross head to observe stress relaxation at fixed load. Stress relaxation rate, s, was found to be stress dependent i.e. it increased with increasing stress levels σ0 both in un-irradiated and irradiated specimens, however the rate was lower in irradiated specimens than those of un-irradiated ones. A further decrease in s was observed with increase in exposure time. The experiential decrease in the relaxation rate in irradiated specimens is ascribed to strong interaction of glide dislocations with radiation induced defects. The activation energy for the movement of dislocations was found to be higher in irradiated specimens as compared with the un-irradiated ones.

  16. Multicapillary electrophoresis disposable cartridge for bioseparations

    Science.gov (United States)

    Amirkhanian, Varoujan D.; Liu, Ming-Sun

    2003-07-01

    We have successfully demonstrated the development of a compact and cost-effective parallel multi-channel capillary electrophoresis system for bio-molecules analysis. The automated process includes a buffer/gel replenishment mechanism, high voltage control of fluidics and an automated sample tray transport capability. The bio-separation/analysis occurs in a disposable cartridge containing multi-column capillaries with integrated excitation optical fibers, detection micro-optics and a buffer reservoir common to all separation channels. Tests of this fully integrated system indicate, that large quantities of biological samples can be analyzed automatically in a short period with highly sensitive fluorescence detection.

  17. High Temperature Tensile Properties of Unirradiated and Neutron Irradiated 20 Cr-35 Ni Austenitic Steel

    Energy Technology Data Exchange (ETDEWEB)

    Roy, R.B.; Solly, B.

    1966-12-15

    The tensile properties of an unirradiated and neutron irradiated (at 40 deg C) 20 % Cr, 35 % Ni austenitic steel have been studied at 650 deg C, 750 deg C and 820 deg C. The tensile elongation and mode of fracture (transgranular) of unirradiated specimens tested at room temperature and 650 deg C are almost identical. At 750 deg C and 820 deg C the elongation decreases considerably and a large part of the total elongation is non-uniform. Furthermore, the mode of fracture at these temperatures is intergranular and microscopic evidence suggests that fracture is caused by formation and linkup of grain boundary cavities. YS and UTS decrease monotonically with temperature. Irradiated specimens show a further decrease in ductility and an increase in the tendency to grain boundary cracking. Irradiation has no significant effect on the YS, but the UTS are reduced. The embrittlement of the irradiated specimens is attributed to the presence of He and Li atoms produced during irradiation and the possible mechanisms are discussed. Prolonged annealing of irradiated and unirradiated specimens at 650 deg C appears to have no significant effect on tensile properties.

  18. Kinetic analysis for non-isothermal decomposition of unirradiated and γ-irradiated indium acetyl acetonate

    Directory of Open Access Journals (Sweden)

    Refaat Mohammed Mahfouz

    2011-03-01

    Full Text Available Kinetic studies for the non-isothermal decomposition of un-irradiated and γ-irradiated indium acetyl acetonate In(acac3 with 10² kGy total γ-ray dose were carried out in static air. The results showed that the decomposition proceeds in one major step in the temperature range of 150-250 °C with the formation of In2O3 as solid residue. The non-isothermal data for un-irradiated and γ-irradiated In(acac3 were analysed using linear Flynn-Wall-Ozawa (FWO and nonlinear Vyazovkin (VYZ iso-conversional methods. The results of application of these free models on the investigated data showed a systematic dependence of Ea on α indicating a simple decomposition process. No significant changes were observed in both decomposition behaviour and (Eα-α dependency between unirradiated and γ-irradiated In(acac3. Calcination of In(acac3 at 400 °C for 5 hours led to the formation of In2O3 monodispersed nanoparticles. X-ray diffraction, FTIR and SEM techniques were employed for characterization of the synthesised nanoparticles. This is the first attempt to prepare In2O3 nanoparticles by solid state thermal decomposition of In(acac3.

  19. Determination of pressure drop across activated carbon fiber respirator cartridges.

    Science.gov (United States)

    Balanay, Jo Anne G; Lungu, Claudiu T

    2016-01-01

    Activated carbon fiber (ACF) is considered as an alternative adsorbent to granular activated carbon (GAC) for the development of thinner, lighter, and efficient respirators because of their larger surface area and adsorption capacities, thinner critical bed depth, lighter weight, and fabric form. This study aims to measure the pressure drop across different types of commercially available ACFs in respirator cartridges to determine the ACF composition and density that will result in acceptably breathable respirators. Seven ACF types in cloth (ACFC) and felt (ACFF) forms were tested. ACFs in cartridges were challenged with pre-conditioned constant air flow (43 LPM, 23°C, 50% RH) at different compositions (single- or combination-ACF type) in a test chamber. Pressure drop across ACF cartridges were obtained using a micromanometer, and compared among different cartridge configurations, to those of the GAC cartridge, and to the NIOSH breathing resistance requirements for respirator cartridges. Single-ACF type cartridges filled with any ACFF had pressure drop measurements (23.71-39.93 mmH2O) within the NIOSH inhalation resistance requirement of 40 mmH2O, while those of the ACFC cartridges (85.47±3.67 mmH2O) exceeded twice the limit due possibly to the denser weaving of ACFC fibers. All single ACFF-type cartridges had higher pressure drop compared to the GAC cartridge (23.13±1.14 mmH2O). Certain ACF combinations (2 ACFF or ACFC/ACFF types) resulted to pressure drop (26.39-32.81 mmH2O) below the NIOSH limit. All single-ACFF type and all combination-ACF type cartridges with acceptable pressure drop had much lower adsorbent weights than GAC (≤15.2% of GAC weight), showing potential for light-weight respirator cartridges. 100% ACFC in cartridges may result to respirators with high breathing resistance and, thus, is not recommended. The more dense ACFF and ACFC types may still be possibly used in respirators by combining them with less dense ACFF materials and/or by

  20. Criticality safety evaluation report for K Basin filter cartridges

    Energy Technology Data Exchange (ETDEWEB)

    Erickson, D.G., Westinghouse Hanford

    1996-08-28

    A criticality safety evaluation of the K Basin filter cartridge assemblies was completed to support operations without criticality alarm system. The results show that for normal operation, the cartridge assembly is far below the safety limit of K eff = 0.95.

  1. Influence of processing on the ethylene-vinyl alcohol (EVOH properties: Application of the successive self-nucleation and annealing (SSA technique

    Directory of Open Access Journals (Sweden)

    2010-03-01

    Full Text Available Films of EVOH copolymers, processed three times by twin-screw extrusion were prepared using a cast-film line. The variation on the melt flow rate (MFR and rheological behaviour of the films were determined, as well as the thermal properties assessed by differential scanning calorimetry (DSC and dynamic-mechanical thermal analysis (DMTA. As the results showed that the reprocessing induced an increase in the viscosity and orientation of the films, it was suggested that structural modifications from chain-extension or cross-linking reactions promoted by hydroxyl and residual acetoxyl groups, could be occurring. The successive self-nucleation and annealing (SSA technique was applied, evidencing the structural modifications on the EVOH copolymer.

  2. Safety Analysis Report for Packaging: The unirradiated fuel shipping container USA/9853/AF

    Energy Technology Data Exchange (ETDEWEB)

    1991-10-18

    The HFBR Unirradiated Fuel Shipping Container was designed and fabricated at the Oak Ridge National Laboratory in 1978 for the transport of fuel for the High Flux Beam Reactor (HFBR) for Brookhaven National Laboratory. The package has been evaluated analytically, as well as the comparison to tests on similar packages, to demonstrate compliance with the applicable regulations governing packages in which radioactive and fissile materials are transported. The contents of this Safety Analysis Report for Packaging (SARP) are based on Regulatory Guide 7.9 (proposed Revision 2 - May 1986), 10 CFR Part 71, DOE Order 1540.2, DOE Order 5480.3, and 49 CFR Part 173.

  3. Safety Analysis Report for Packaging: The unirradiated fuel shipping container USA/9853/AF

    Energy Technology Data Exchange (ETDEWEB)

    1991-10-18

    The HFBR Unirradiated Fuel Shipping Container was designed and fabricated at the Oak Ridge National Laboratory in 1978 for the transport of fuel for the High Flux Beam Reactor (HFBR) for Brookhaven National Laboratory. The package has been evaluated analytically, as well as the comparison to tests on similar packages, to demonstrate compliance with the applicable regulations governing packages in which radioactive and fissile materials are transported. The contents of this Safety Analysis Report for Packaging (SARP) are based on Regulatory Guide 7.9 (proposed Revision 2 - May 1986), 10 CFR Part 71, DOE Order 1540.2, DOE Order 5480.3, and 49 CFR Part 173.

  4. Filter quality of pleated filter cartridges.

    Science.gov (United States)

    Chen, Chun-Wan; Huang, Sheng-Hsiu; Chiang, Che-Ming; Hsiao, Ta-Chih; Chen, Chih-Chieh

    2008-04-01

    The performance of dust cartridge filters commonly used in dust masks and in room ventilation depends both on the collection efficiency of the filter material and the pressure drop across the filter. Currently, the optimization of filter design is based only on minimizing the pressure drop at a set velocity chosen by the manufacturer. The collection efficiency, an equally important factor, is rarely considered in the optimization process. In this work, a filter quality factor, which combines the collection efficiency and the pressure drop, is used as the optimization criterion for filter evaluation. Most respirator manufacturers pleat the filter to various extents to increase the filtration area in the limit space within the dust cartridge. Six sizes of filter holders were fabricated to hold just one pleat of filter, simulating six different pleat counts, ranging from 0.5 to 3.33 pleats cm(-1). The possible electrostatic charges on the filter were removed by dipping in isopropyl alcohol, and the air velocity is fixed at 100 cm s(-1). Liquid dicotylphthalate particles generated by a constant output atomizer were used as challenge aerosols to minimize particle loading effects. A scanning mobility particle sizer was used to measure the challenge aerosol number concentrations and size distributions upstream and downstream of the pleated filter. The pressure drop across the filter was monitored by using a calibrated pressure transducer. The results showed that the performance of pleated filters depend not only on the size of the particle but also on the pleat count of the pleated filter. Based on filter quality factor, the optimal pleat count (OPC) is always higher than that based on pressure drop by about 0.3-0.5 pleats cm(-1). For example, the OPC is 2.15 pleats cm(-1) from the standpoint of pressure drop, but for the highest filter quality factor, the pleated filter needed to have a pleat count of 2.65 pleats cm(-1) at particle diameter of 122 nm. From the aspect of

  5. Rescue effects in radiobiology: Unirradiated bystander cells assist irradiated cells through intercellular signal feedback

    Energy Technology Data Exchange (ETDEWEB)

    Chen, S. [Department of Physics and Materials Science, City University of Hong Kong, Tat Chee Avenue, Kowloon Tong (Hong Kong); Key Laboratory of Ion Beam Bioengineering, Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China); Zhao, Y. [Key Laboratory of Ion Beam Bioengineering, Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China); Han, W. [Department of Physics and Materials Science, City University of Hong Kong, Tat Chee Avenue, Kowloon Tong (Hong Kong); Chiu, S.K. [Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon Tong (Hong Kong); Zhu, L. [Office of Admission and Careers Advisory Service, Shenzhen University, Shenzhen 518060 (China); Wu, L. [Key Laboratory of Ion Beam Bioengineering, Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China); Yu, K.N., E-mail: peter.yu@cityu.edu.hk [Department of Physics and Materials Science, City University of Hong Kong, Tat Chee Avenue, Kowloon Tong (Hong Kong)

    2011-01-10

    Mammalian cells respond to ionization radiation by sending out extracellular signals to affect non-irradiated neighboring cells, which is referred to as radiation induced bystander effect. In the present paper, we described a phenomenon entitled the 'rescue effects', where the bystander cells rescued the irradiated cells through intercellular signal feedback. The effect was observed in both human primary fibroblast (NHLF) and cancer cells (HeLa) using two-cell co-culture systems. After co-culturing irradiated cells with unirradiated bystander cells for 24 h, the numbers of 53BP1 foci, corresponding to the number of DNA double-strand breaks in the irradiated cells were less than those in the irradiated cells that were not co-cultured with the bystander cells (0.78 {+-} 0.04 foci/cell vs. 0.90 {+-} 0.04 foci/cell) at a statistically significant level. Similarly, both micronucleus formation and extent of apoptosis in the irradiated cells were different at statistically significant levels if they were co-cultured with the bystander cells. Furthermore, it was found that unirradiated normal cells would also reduce the micronucleus formation in irradiated cancer cells. These results suggested that the rescue effects could participate in repairing the radiation-induced DNA damages through a media-mediated signaling feedback, thereby mitigating the cytotoxicity and genotoxicity of ionizing radiation.

  6. [Enforcement of type M 20 cal. 4 mm cartridges].

    Science.gov (United States)

    Dobosz, Tadeusz; Jaworski, Ryszard; Kawecki, Jerzy; Semiczek, Wiesław; Trnka, Jakub

    2002-01-01

    The aim of the paper was to investigate and compare the speed and energy of a bullet from 4 mm cal. cartridges of central ignition type M20, both original and transformed by addition of different kinds of propellants. Original cartridges are characterized by an average speed of the bullet of 144 m/s and average energy of 4.8 J. After transformation by the addition of on an average 31.3 mg of smokeless powder from a cartridge type LR'22, a maximum bullet speed of 299 m/s (average) and maximum energy of 21.2 joule (average) were reached. Our test showed that shots using transformed ammunition type M 20 cal. 4 mm can be dangerous for both health and life. Multiple M20 shot wounds may be very similar to single shot wounds caused by a shotshell cartridge fired from a shotgun weapon.

  7. Construction and optimisation of a cartridge filter for removing ...

    African Journals Online (AJOL)

    Construction and optimisation of a cartridge filter for removing fluoride in drinking water. ... It was found that the optimal conditions for the F- filter that gave the best results in removing of F- from water with minimum ... Article Metrics.

  8. Overview and Critical Assessment of the Tensile Properties of unirradiated and irradiated EUROFER97

    Energy Technology Data Exchange (ETDEWEB)

    Lucon, E.; Vandermeulen, W.

    2007-10-15

    Material research represents a crucial issue for the assessment of fusion as a future viable source of energy. Structural materials, in particular, need to show a superior mechanical and chemical behaviour to guarantee the safe operation of the reactor during its whole lifetime, while retaining low activation characteristics to minimise the environmental impact of the produced waste. In this context, specific efforts have been focused for the last twenty years in Europe, Japan and the US, on developing suitable Reduced Activation Ferritic Martensitic (RAFM) steels as candidate structural materials. EUROFER97 has recently emerged in Europe as the reference material for the DEMO design. In the framework of the Long-Term Programme of EFDA (European Fusion Development Agreement), a coordinated effort has been launched aimed at providing a critical assessment of the mechanical and microstructural properties of EUROFER97 in the unirradiated and irradiated conditions, based on the results accumulated since the late 90ies within numerous EFDA tasks.

  9. Reactor Materials Program electrochemical potential measurements by ORNL with unirradiated and irradiated stainless steel specimens

    Energy Technology Data Exchange (ETDEWEB)

    Baumann, E.W.; Caskey, G.R. Jr.

    1993-07-01

    Effect of irradiation of stainless steel on electrochemical potential (ECP) was investigated by measurements in dilute HNO{sub 3} and H{sub 2}O{sub 2} solutions, conditions simulating reactor moderator. The electrodes were made from unirradiated/irradiated, unsensitized/sensitized specimens from R-reactor piping. Results were inconclusive because of budgetary restrictions. The dose rate may have been too small to produce a significant radiolytic effect. Neither the earlier CERT corrosion susceptibility tests nor the present ECP measurements showed a pronounced effect of irradiation on susceptibility of the stainless steel to IGSCC; this is confirmed by the absence in the stainless steel of the SRS reactor tanks (except for the C Reactor tank knuckle area).

  10. Sperm quantity and size variation in un-irradiated and irradiated males of the malaria mosquito Anopheles arabiensis Patton

    NARCIS (Netherlands)

    Helinski, M.; Knols, B.G.J.

    2009-01-01

    Anopheles mosquitoes are important candidates for genetic control strategies. However, little is known about sperm quality and quantity as determinants of male reproductive success. In this study, sperm quantity and length variation were assessed in testes of un-irradiated and irradiated Anopheles

  11. Sperm quantity and size variation in un-irradiated and irradiated males of the malaria mosquito Anopheles arabiensis Patton

    NARCIS (Netherlands)

    Helinski, M.; Knols, B.G.J.

    2009-01-01

    Anopheles mosquitoes are important candidates for genetic control strategies. However, little is known about sperm quality and quantity as determinants of male reproductive success. In this study, sperm quantity and length variation were assessed in testes of un-irradiated and irradiated Anopheles a

  12. Obtention of fracture properties of unirradiated fuel cladding from ring compression tests

    Energy Technology Data Exchange (ETDEWEB)

    Martin-Rengel, M.A. [Departamento de Ciencia de Materiales, UPM, E.T.S.I. Caminos, Canales y Puertos Profesor Aranguren s/n, E-28040 Madrid (Spain); Consejo de Seguridad Nuclear (CSN), Justo Dorado 11, E-28040 Madrid (Spain); Gomez, F.J.; Ruiz-Hervias, J.; Caballero, L.; Valiente, A. [Departamento de Ciencia de Materiales, UPM, E.T.S.I. Caminos, Canales y Puertos Profesor Aranguren s/n, E-28040 Madrid (Spain)

    2009-06-15

    Zirconium alloy cladding is used as the first structural barrier to contain the nuclear fuel and the fission products. In addition to its neutron transparency, this material has a good corrosion resistance and remarkable mechanical properties at operational temperatures. Consequently, it is or paramount importance to precisely characterize the mechanical behaviour and fracture properties of irradiated cladding to ensure a safe operation. It is known that the mechanical behaviour of unirradiated zirconium alloy cladding is anisotropic. The elastoplastic response depends on the direction, namely radial, hoop or longitudinal. For this reason, different fracture properties should be expected in each direction. From the various tests employed to characterize the mechanical behaviour along the hoop direction in nuclear fuel cladding, the ring compression test is particularly useful to study material fracture. With this test it is possible to determine the moment when a real crack is formed, due to a sudden decrease in the applied load at a given displacement value. The aim of this research is to determine as precisely as possible the value of the fracture energy from the ring compression test load vs. displacement curves. To this end, a finite element calculation incorporating the cohesive zone model was performed. In this case, the cohesive zone theory is applied in its simplest form. It is considered that the cohesive crack transfers a constant stress until the displacement of this cohesive crack reaches a critical value. At this precise moment a real crack is generated. The properties of the softening curve of the cohesive zone model can be obtained by directly comparing the experimental load vs. displacement records with the finite element calculations. The area under the softening curve is the fracture energy, which is directly related with the material fracture toughness. The experimental data used in this work have been obtained on unirradiated Zirlo cladding

  13. From SCORM to Common Cartridge: A Step Forward

    Science.gov (United States)

    Gonzalez-Barbone, Victor; Anido-Rifon, Luis

    2010-01-01

    Shareable Content Object Reference Model (SCORM) was proposed as a standard for sharable learning object packaging, delivering and sequencing. Several years later, Common Cartridge (CC) is proposed as an enhancement of SCORM offering more flexibility and addressing needs not originally envisioned, namely assessment and web 2.0 standards, content…

  14. Ballistics of the 30-06 Rifle Cartridge

    Science.gov (United States)

    2012-11-30

    www.hodgdon.com/PDF/Youth%20Loads.pdf. 14. Endris, Graham. DETAIL SPECIFICATION CARTRIDGE,.300 WINCHESTER MAGNUM MATCH, MK 248 MOD 1 DODIC AB43...Jason T. Gomez and Arun Shukla November 2001, pp. 965-979. 10, November 2001, International Journal of Impact Engineering, Vol. 25, pp. 965-979

  15. EVALUATING A COMPOSITE CARTRIDGE FOR SMALL SYSTEM DRINKING WATER TREATMENT

    Science.gov (United States)

    A multi-layer, cartridge-based system that combines physical filtration with carbon adsorption and ultraviolet (UV) light disinfection has been developed to perform as a water treatment security device to protect homes against accidental or intentional contaminant events. A seri...

  16. EVALUATING A COMPOSITE CARTRIDGE FOR SMALL SYSTEM DRINKING WATER TREATMENT

    Science.gov (United States)

    A multi-layer, cartridge-based system that combines physical filtration with carbon adsorption and ultraviolet (UV) light disinfection has been developed to perform as a water treatment security device to protect homes against accidental or intentional contaminant events. A seri...

  17. High resolution X-ray diffraction studies on unirradiated and irradiated strontium hexaferrite crystals

    Indian Academy of Sciences (India)

    Balwinder Kaur; Monita Bhat; F Licci; Ravi Kumar; K K Bamzai; P N Kotru

    2012-04-01

    High-resolution X-ray diffraction technique, employing a three-crystal monochromator–collimator combination is used to study the irradiation induced defects in flux grown Sr-hexaferrite crystals irradiated with 50 MeV Li3+ ion beams at room temperature with a fluence value of 1 × 1014 ions/cm2. The diffraction curves of the irradiated crystals suggest the possibility of creation of low angle grain boundaries and other point/clusters of defects causing amorphization in the irradiated crystals. The perfection of the irradiated and unirradiated (0001) cleaved surfaces of the crystals is studied using the bulk method of X-ray topography. The topographs supplement the findings suggestive of modifications in the crystalline quality of SrFe12O19 on irradiation with SHI of Li3+. Etching of the (0001) cleaved surfaces in H3PO4 at 120°C suggests that the dissolution characteristics of the surfaces get affected on irradiation with SHI of Li3+, besides supporting the findings of HRXRD and X-ray topography regarding modifications in the perfection of SrFe12O19 on irradiation.

  18. Properties of unirradiated and irradiated Ti-6Al-4V alloy for ITER flexible connectors

    Energy Technology Data Exchange (ETDEWEB)

    Rodchenkov, B.S., E-mail: rodchen@nikiet.ru [Research and Development Institute of Power Engineering (RDIPE), P.O. Box 788, Moscow 101000 (Russian Federation); Evseev, M.V. [Institute of Reactor Materials, Zarechnyi, Sverdlovsk Region 624051 (Russian Federation); Strebkov, Yu.S. [Research and Development Institute of Power Engineering (RDIPE), P.O. Box 788, Moscow 101000 (Russian Federation); Sinelnikov, L.P.; Shushlebin, V.V. [Institute of Reactor Materials, Zarechnyi, Sverdlovsk Region 624051 (Russian Federation)

    2011-10-01

    The high strength ({alpha} + {beta}) Ti-6Al-4V alloy was selected as the material for flexible attachments of the shield blanket modules in the ITER reactor. The different technologies used for manufacturing this alloy are: forging, stamping or pressing. The microstructures resulting from these processing methods can vary significantly and as a consequence the properties, including irradiation behavior, also vary. There are limited data available on the irradiation behavior of these materials. Specimens cut in the longitudinal and transversal directions of forged and stamped material were studied, with some of the specimens hydrogen charged to {approx}400 ppm H{sub 2}. In the unirradiated condition the forged alloy had slightly more ductility than the stamped alloy. The strength properties of both were practically the same. Neutron irradiation of these materials in the IVV-2M reactor reached doses of {approx}0.2 and 0.3 dpa at temperatures 240-260 deg. C. Irradiation resulted in substantial hardening and significant decrease of the fracture toughness of specimens from both materials.

  19. 42 CFR 84.253 - Chemical-cartridge respirators; requirements and tests.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Chemical-cartridge respirators; requirements and... DEVICES Special Use Respirators § 84.253 Chemical-cartridge respirators; requirements and tests. (a... for chemical-cartridge respirators prescribed in Subpart L of this part are applicable to...

  20. 49 CFR 173.230 - Fuel cell cartridges containing hazardous material.

    Science.gov (United States)

    2010-10-01

    ...) For fuel cell cartridges contained in equipment, fuel cell systems must not charge batteries during... 49 Transportation 2 2010-10-01 2010-10-01 false Fuel cell cartridges containing hazardous material... Than Class 1 and Class 7 § 173.230 Fuel cell cartridges containing hazardous material. (a)...

  1. Refilling of carbon nanotube cartridges for 3D nanomanufacturing

    Science.gov (United States)

    Bekarevich, Raman; Toyoda, Masami; Baba, Shuichi; Nakata, Toshihiko; Hirahara, Kaori

    2016-03-01

    Metal-filled carbon nanotubes (CNTs) are known to be used as pen-tip injectors for 3D manufacturing on the nanoscale. However, the CNT interior cannot accumulate enough material to fabricate complex metallic nanostructures. Therefore a method for refilling the CNT cartridge needs to be developed. The strategy for refilling of CNT cartridges is suggested in this study. Controlled growth of gold nanowires in the interior of isolated CNTs using a real-time manipulator installed in a transmission electron microscope is reported herein. The encapsulation process of discrete gold nanoparticles in the hollow spaces of open-ended multi-wall CNTs was evaluated in detail. The experimental results reveal that the serial loading of isolated gold nanoparticles allows the control of the length of the loaded nanowires with nanometer accuracy. Thermophoresis and the coalescence of gold nanoparticles are assumed to be the primary mechanisms responsible for gold loading into a CNT cartridge.Metal-filled carbon nanotubes (CNTs) are known to be used as pen-tip injectors for 3D manufacturing on the nanoscale. However, the CNT interior cannot accumulate enough material to fabricate complex metallic nanostructures. Therefore a method for refilling the CNT cartridge needs to be developed. The strategy for refilling of CNT cartridges is suggested in this study. Controlled growth of gold nanowires in the interior of isolated CNTs using a real-time manipulator installed in a transmission electron microscope is reported herein. The encapsulation process of discrete gold nanoparticles in the hollow spaces of open-ended multi-wall CNTs was evaluated in detail. The experimental results reveal that the serial loading of isolated gold nanoparticles allows the control of the length of the loaded nanowires with nanometer accuracy. Thermophoresis and the coalescence of gold nanoparticles are assumed to be the primary mechanisms responsible for gold loading into a CNT cartridge. Electronic

  2. Descemet′s tear due to injector cartridge tip deformity

    Directory of Open Access Journals (Sweden)

    Partha Biswas

    2012-01-01

    Full Text Available Foldable intraocular lens (IOL implantation using an injector system through 2.8-mm clear corneal incision following phacoemulsification provides excellent speedy postoperative recovery. In our reported case, a Sensar AR40e IOL (Abbott Medical Optics, USA was loaded into Emerald C cartridge, outside the view of the operating microscope, by the first assistant. The surgeon proceeded with the IOL injection through a 2.8-mm clear corneal incision after uneventful phacoemulsification, immediately following which he noted a Descemet′s tear with a rolled out flap of about 2 mm near the incision site. Gross downward beaking of the bevelled anterior end of the cartridge was subsequently noticed upon examination under the microscope. We suggest careful preoperative microscopic inspection of all instruments and devices entering the patient′s eyes to ensure maximum safety to the patient.

  3. [Morphologic detection of Bacillus cereus in blank cartridges].

    Science.gov (United States)

    Rothschild, M A; Mülling, C

    1998-01-01

    Wound infections after gunshot wounds from live ammunition can produce serious complications. It is well known that projectiles per se are neither sterile nor does their firing cause sterilization. The germs on the surface of a projectile enter the body together with the projectile and are thus introduced into the wound together with skin bacteria. However it is less known that wound infections can occur in wounds caused by the gas jet from blank ammunition (mainly from shots at very close range). In such ammunition without a projectile, the propellant particles are usually contaminated with bacteria which find their way into the wound together with skin germs. In previous investigations, we have microbiologically detected the species Bacillus cereus in the propellant of blank cartridges. In the present study, we have applied scanning electron microscopic methods to find out which areas of the blank cartridges are colonized by these bacteria. For this purpose 20 blank cartridges, each from 4 different manufacturers, were electronmicroscopically examined. B. cereus only found on the surface of intact nitrocellulose particles but not in the interior of broken prepared propellant particles. Bacterial structures were not morphologically identified on black powder particles.

  4. Subtask 12D6: Fatigue behavior of unirradiated V-5Cr-5Ti

    Energy Technology Data Exchange (ETDEWEB)

    Gieseke, B.G.; Stevens, C.O.; Grossbeck, M.L. [Oak Ridge National Lab., TN (United States)

    1995-03-01

    The objective of this research is to determine the low cycle fatigue behavior of V-5Cr-5Ti alloys for a range of temperatures and the extent of environmental effects at ambient temperatures. The results of in-vacuum low cycle fatigue tests are presented for unirradiated V-5Cr-5Ti tested at room temperature (25, 250, and 400{degrees}C). A comparison of the fatigue data generated in rough and high vacuums shows that a pronounced environmental degradation of the fatigue properties exists in the alloy at room temperature. Fatigue life was reduced by as much as 84%. Cyclic stress range data and SEM observations suggest that this reduction is due to a combination of increases in rates of crack initiation and subsequent growth. The relative contribution of each difference is dependent upon the strain range. In high vacuum, the fatigue results also show a trend of increasing cyclic life with increasing temperature between 25 and 400{degrees}C. From the limited data available, life at 25{degrees}C averages 1.7 times that at 25{degrees}C, and at 400{degrees}C, life averages 3.2 times that at room temperature. Like the environmental effects at 25{degrees}C, the effect of temperature seems to be a function of strain range at each temperature. The total strain range and cycles to failure were correlated using a power law relationship and compared to 20% cold-worked 316 stainless steel and several vanadium-base alloys. The results suggest that V-SCr-5Ti has better resistance to fatigue than 316-SS in the temperature range of 25 to 400{degrees}C. At 400{degrees}C, the data also show that V-5Cr-5Ti out performs Vanstar alloys 7 and 8 over the entire range of strains investigated. Furthermore, the fatigue properties of the V-5Cr-5Ti alloy compare favorably to V-15Cr-57i (at 25{degrees}C) and Vanstar 9 (at 400{degrees}C) at strains greater than 1%. At lower strains, the lower fatigue resistance of V-5Cr-5Ti is attributed to the higher strengths of the V-15Cr-5Ti and Vanstar 9 alloys.

  5. Comparison of ring compression testing to three point bend testing for unirradiated ZIRLO cladding

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2015-04-01

    Safe shipment and storage of nuclear reactor discharged fuel requires an understanding of how the fuel may perform under the various conditions that can be encountered. One specific focus of concern is performance during a shipment drop accident. Tests at Savannah River National Laboratory (SRNL) are being performed to characterize the properties of fuel clad relative to a mechanical accident condition such as a container drop. Unirradiated ZIRLO tubing samples have been charged with a range of hydride levels to simulate actual fuel rod levels. Samples of the hydrogen charged tubes were exposed to a radial hydride growth treatment (RHGT) consisting of heating to 400°C, applying initial hoop stresses of 90 to 170 MPa with controlled cooling and producing hydride precipitates. Initial samples have been tested using both a) ring compression test (RCT) which is shown to be sensitive to radial hydride and b) three-point bend tests which are less sensitive to radial hydride effects. Hydrides are generated in Zirconium based fuel cladding as a result of coolant (water) oxidation of the clad, hydrogen release, and a portion of the released (nascent) hydrogen absorbed into the clad and eventually exceeding the hydrogen solubility limit. The orientation of the hydrides relative to the subsequent normal and accident strains has a significant impact on the failure susceptability. In this study the impacts of stress, temperature and hydrogen levels are evaluated in reference to the propensity for hydride reorientation from the circumferential to the radial orientation. In addition the effects of radial hydrides on the Quasi Ductile Brittle Transition Temperature (DBTT) were measured. The results suggest that a) the severity of the radial hydride impact is related to the hydrogen level-peak temperature combination (for example at a peak drying temperature of 400°C; 800 PPM hydrogen has less of an impact/ less radial hydride fraction than 200 PPM hydrogen for the same thermal

  6. Development of STR profiles from firearms and fired cartridge cases.

    Science.gov (United States)

    Horsman-Hall, Katie M; Orihuela, Yvette; Karczynski, Stephanie L; Davis, Ann L; Ban, Jeffrey D; Greenspoon, Susan A

    2009-09-01

    Fired cartridge cases are a common type of evidence found at crime scenes. However, due to the high chamber temperatures and touch nature of this evidence, DNA testing is not commonly sought because it is believed DNA is only present in low levels, whether it is due to initial low levels of DNA and/or DNA degradation from the heat or inhibition of the PCR reaction. Moreover, very few laboratories report STR typing success with fired cases. This study focused on obtaining STR profiles from fired cartridge cases using the AmpFlSTR MiniFiler kit, which is designed to amplify DNA from low level, inhibited, and degraded samples. Comparisons to other STR amplification kits were also conducted. In attempt to simulate casework, random individuals loaded cartridges into a firearm. DNA was recovered from the fired cartridge cases using the double swab technique and extracted using an automated large volume DNA IQ method. Initially, testing focused on known shedders handling cartridges for 30s prior to firing. A significantly greater number of alleles was obtained following amplification with the MiniFiler kit versus the PowerPlex 16 BIO kit. No alleles were observed using the Identifiler kit. In an attempt to better simulate casework, a random selection of laboratory personnel handled shotshells for as long as needed to load and fire the weapon. In this mock sample study, the MiniFiler kit successfully amplified an average of 22% of expected alleles from DNA recovered from shotshell cases versus the PowerPlex 16 BIO kit where an average of 7% of alleles were observed. However, the total number of alleles obtained from the two kits was not significantly different. The quality of the DNA obtained from fired cases was studied with evidence of inhibition in at least 11% of shotshell case samples. After swabbing the head and the hull of three shotshell cases separately, a significantly greater number of alleles was obtained from the hull as opposed to the head of the fired

  7. Mechanical properties of type 316L stainless steel welded joint for ITER vacuum vessel (1). Experiment of unirradiated welded joint

    Energy Technology Data Exchange (ETDEWEB)

    Saito, Shigeru; Fukaya, Kiyoshi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Ishiyama, Shintaro [Japan Atomic Energy Research Inst., Oarai, Ibaraki (Japan). Oarai Research Establishment; Takahashi, Hiroyuki; Koizumi, Kouichi [Japan Atomic Energy Research Inst., Naka, Ibaraki (Japan). Naka Fusion Research Establishment

    2001-01-01

    In design activity of ITER, the vacuum vessel (VV) is ranked as one of the most important components in core reactor from the view point of first barrier to tritium release from the reactor. The VV of ITER is designed as double walled structure so that some parts of them are not qualified in the conventional design standards. So it is necessary to prepare the new design standards to be applied them. JAERI has executed the preparation activity of the new design standards and the technical data to support them. In this study, the results of metallographic observation and mechanical properties of unirradiated type 316L stainless steel welded joint were reported. (author)

  8. Properties of unirradiated fuel element graphites H-451 and SO818. [Bulk density, tensile properties, thermal expansion, thermal conductivity

    Energy Technology Data Exchange (ETDEWEB)

    Engle, G.B.; Johnson, W.R.

    1976-10-08

    Nuclear graphites H-451, lot 440 (Great Lakes Carbon Corporation (GLCC)), and SO818 (Airco Speer Division, Air Reduction Corporation (AS)) are described, and physical, mechanical, and chemical property data are presented for the graphites in the unirradiated state. A summary of the mean values of the property data and of data on TS-1240 and H-451, lot 426, is tabulated. A direct comparison of H-451, lot 426, chosen for Fort St. Vrain (FSV) fuel reload production, TS-1240, and SO818 may be made from the table. (auth)

  9. Dissolution of unirradiated UO{sub 2} fuel in synthetic groundwater. Final report (1996-1998)

    Energy Technology Data Exchange (ETDEWEB)

    Ollila, K. [VTT Chemical Technology, Espoo (Finland)

    1999-05-01

    This study was a part of the EU R and D programme 1994-1998: Nuclear Fission Safety, entitled `Source term for performance assessment of spent fuel as a waste form`. The research carried out at VTT Chemical Technology was focused on the effects of granitic groundwater composition and redox conditions on UO{sub 2} solubility and dissolution mechanisms. The synthetic groundwater compositions simulated deep granitic fresh and saline groundwaters, and the effects of the near-field material, bentonite, on very saline groundwater. Additionally, the Spanish granite/bentonite water was used. The redox conditions (Eh), which are obviously the most important factors that influence on UO{sub 2} solubility under the disposal conditions of spent fuel, varied from strongly oxidising (air-saturated), anaerobic (N{sub 2}, O{sub 2} < l ppm) to reducing (N{sub 2}, low Eh). The objective of the air-saturated dissolution experiments was to yield the maximum solution concentrations of U, and information on the formation of secondary phases that control the concentrations, with different groundwater compositions. The static batch solubility experiments of long duration (up to 1-2 years) were performed using unirradiated UO{sub 2} pellets and powder. Under anaerobic and reducing conditions, the solubilities were also approached from oversaturation. The results of the oxic, air-saturated dissolution experiments with UO{sub 2} powder showed that the increase in the salinity (< 1.7 M) had a minor effect on the measured steady-state concentrations of U. The concentrations, (1.2 ...2.5) x 10{sup -5} M, were at the level of the theoretical solubility of schoepite or another uranyl oxide hydrate, e.g. becquerelite (possibly Na-polyuranate). The higher alkalinity of the fresh (Allard) composition increased the aqueous U concentration. Only some kind of oxidised U-phase (U{sub 3}O{sub 8}-UO{sub 3}) was identified with XRD when studying possible secondary phases after the contact time of one year

  10. New method to calculate the mechanical properties of unirradiated fuel cladding from ring tensile tests

    Energy Technology Data Exchange (ETDEWEB)

    Martin-Rengel, M.A. [Departamento de Ciencia de Materiales, UPM, E.T.S.I. Caminos, Canales y Puertos, Profesor Aranguren s/n, E-28040 Madrid (Spain); Consejo de Seguridad Nuclear (CSN), Justo Dorado 11, E-28040 Madrid (Spain); Gomez, F.J.; Ruiz-Hervias, J.; Caballero, L.; Valiente, A. [Departamento de Ciencia de Materiales, UPM, E.T.S.I. Caminos, Canales y Puertos, Profesor Aranguren s/n, E-28040 Madrid (Spain)

    2009-06-15

    displacement of the loading piece and another one between the equivalent stress in the same point and the nominal applied stress. In the first iteration a calculation is performed with an approximate plastic stress-strain law, and the two above-mentioned relationships are used to determine a new law from the experimental results. In the second iteration the calculation takes into account the new plastic stress-strain law and determines two new relationships. After a few iterations an excellent fit is obtained. This method is an improvement of the original method by Arsene and Bai [3] and allows obtaining the plastic stress-strain curve in the hoop direction in a consistent way. The experimental data used in this work to check the validity of the procedure have been obtained on unirradiated Zirlo cladding, with the standard alloy composition and geometry (outer diameter of the cladding 9.5 mm and a wall thickness of 0.56 mm). References: [1]. Arsene, S.; Bai, J.B. A new approach to measuring transverse properties of structural tubing by a ring test, Journal of Testing and Evaluation, 24: 386-391 (1996) [2]. Arsene, S.; Bai, J. 'A new approach to measuring transverse properties of structural tubing by a ring test-experimental investigation', Journal of Testing and Evaluation, 26: 26-30 (1998) [3]. Arsene, S.; Bai, J.B.; 'Hydride embrittlement and irradiation effects on the hoop mechanical properties of pressurized water reactor (PWR) and boiling-water reactor (BWR) zircaloy cladding tubes: Part I. Hydride embrittlement in stress-relieved, annealed, and recrystallized zircaloys at 20 deg. C and 300 deg. C', Metallurgical and materials and transactions A, 34A: 553-566 (2003) [4]. Chang-Sun Seok, Bong-Kook, K.Linga, 'The properties of the ring and burst creep of zirlo claddings', Engineering Failure Analysis, 13: 389-397 (2006). (authors)

  11. An integratable microfluidic cartridge for forensic swab samples lysis.

    Science.gov (United States)

    Yang, Jianing; Brooks, Carla; Estes, Matthew D; Hurth, Cedric M; Zenhausern, Frederic

    2014-01-01

    Fully automated rapid forensic DNA analysis requires integrating several multistep processes onto a single microfluidic platform, including substrate lysis, extraction of DNA from the released lysate solution, multiplexed PCR amplification of STR loci, separation of PCR products by capillary electrophoresis, and analysis for allelic peak calling. Over the past several years, most of the rapid DNA analysis systems developed started with the reference swab sample lysate and involved an off-chip lysis of collected substrates. As a result of advancement in technology and chemistry, addition of a microfluidic module for swab sample lysis has been achieved in a few of the rapid DNA analysis systems. However, recent reports on integrated rapid DNA analysis systems with swab-in and answer-out capability lack any quantitative and qualitative characterization of the swab-in sample lysis module, which is important for downstream forensic sample processing. Maximal collection and subsequent recovery of the biological material from the crime scene is one of the first and critical steps in forensic DNA technology. Herein we present the design, fabrication and characterization of an integratable swab lysis cartridge module and the test results obtained from different types of commonly used forensic swab samples, including buccal, saliva, and blood swab samples, demonstrating the compatibility with different downstream DNA extraction chemistries. This swab lysis cartridge module is easy to operate, compatible with both forensic and microfluidic requirements, and ready to be integrated with our existing automated rapid forensic DNA analysis system. Following the characterization of the swab lysis module, an integrated run from buccal swab sample-in to the microchip CE electropherogram-out was demonstrated on the integrated prototype instrument. Therefore, in this study, we demonstrate that this swab lysis cartridge module is: (1) functionally, comparable with routine benchtop lysis

  12. Continuous plasma perfusion of dual cartridges in series: rationale and early clinical experience.

    Science.gov (United States)

    Sun, Liang; Yan, Peng-Bo; Zhang, Yu-Hua; Wei, Lu-Qing; Li, Guo-Qiang

    2016-12-01

    To improve the efficiency of plasma perfusion on eliminating plasma paraquat (PQ), we designed continuous plasma perfusion of dual cartridges in series (CPPDCS) on Diapact Braun CRRT machine. The goals of this study were to evaluate the effective of CPPDCS on paraquat removal in patients with acute paraquat intoxication. Our results show that the PQ clearance rate of dual cartridges was significantly higher than that of single cartridge at 1st, 2nd, 3(rd), and 4th plasma perfusion. Compared with single-cartridge plasma perfusion, CPPDCS significantly reduced the frequency of cartridge replacement, shorten the time of perfusion. These results indicate that CPPDCS is effective than plasma perfusion of single cartridge on PQ clearance rate and may provide an effective treatment for PQ poisoning.

  13. A comparative study of combustible cartridge case materials

    Directory of Open Access Journals (Sweden)

    Wei-tao Yang

    2017-06-01

    Full Text Available Foamed combustible material based on polymer bonded RDX was fabricated using CO2 as foaming agent. The inner structures of felted and foamed combustible materials were presented by SEM. The two materials presented different formulations and inner porous structures. The combustion behaviors of felted and foamed materials were investigated by closed vessel test. Simultaneously, the co-combustion behavior of combustible cartridge case with 7-perf consolidated propellants was also investigated. The results of closed vessel test is applicable to gun system which is made of the foamed combustible material as component.

  14. Solid cartridge for a pulse weld forming electrode and method of joining tubular members

    Energy Technology Data Exchange (ETDEWEB)

    Bonnen, John Joseph Francis; Golovashchenko, Sergey Fedorovich; Mamutov, Alexander; Maison, Lloyd Douglas; Dawson, Scott Alwyn; deVries, James

    2016-02-23

    A cartridge assembly is disclosed for a pulse welding a first tube supported on a mandrel to a second tube. An outer tool is assembled over the second tube and a stored charge is discharged in the cartridge assembly. The cartridge comprises an annular conductor and a solid casing enveloping the conductor. The stored charge is electrically connected to the conductor and discharged through the conductor to compress the second tube and pulse weld the second tube to the first tube.

  15. The effects of laser welding on heterogeneous immunoassay performance in a microfluidic cartridge

    Science.gov (United States)

    Mäntymaa, Anne; Halme, Jussi; Välimaa, Lasse; Kallio, Pasi

    2011-01-01

    Sealing of a microfluidic cartridge is a challenge, because the cartridge commonly contains heat-sensitive biomolecules that must also be protected from contamination. In addition, the objective is usually to obtain a sealing method suitable for mass production. Laser welding is a rapid technique that can be accomplished with low unit costs. Even though the technique has been widely adopted in industry, the literature on its use in microfluidic applications is not large. This paper is the first to report the effects of laser welding on the performance of the heterogeneous immunoassay in a polystyrene microfluidic cartridge in which biomolecules are immobilized into the reaction surface of the cartridge before sealing. The paper compares the immunoassay performance of microfluidic cartridges that are sealed either with an adhesive tape or by use of laser transmission welding. The model analyte used is thyroid stimulating hormone (TSH). The results show that the concentration curves in the laser-welded cartridges are very close to the curves in the taped cartridges. This indicates, first, that laser welding does not cause any significant reduction in immunoassay performance, and second, that the polystyrene cover does not have significant effect on the signal levels. Interestingly, the coefficients of variance between parallel samples were lower in the laser-welded cartridges than in the taped cartridges. PMID:22685505

  16. Tritium release from a nonevaportable getter-pump cartridge exposed to moist air at ambient temperature

    Energy Technology Data Exchange (ETDEWEB)

    Biel, T.J.; Sherwood, A.E.; Singleton, M.F.; Alire, R.M.

    1979-07-10

    The amount of tritium released when a commercially available getter-pump cartridge was exposed to moist air at ambient temperatures was measured. The cartridge consisted of Zr-Al powder pressed onto an iron substrate, which is the type of cartridge proposed for use in the Tokomak Fusion Test Reactor. While the initial release of tritium was rapid the total activity released was lss than 0.005% of the cartridge loading. Of this amount, at least 80% was released as tritiated water. 8 figures.

  17. Special Analysis for the Disposal of the INL Waste Associated with the Unirradiated Light Water Breeder Reactor (LWBR) Waste Stream at the Area 5 Radioactive Waste Management Site

    Energy Technology Data Exchange (ETDEWEB)

    Shott, Gregory [National Security Technologies, LLC, Las Vegas, NV (United States)

    2017-03-21

    This special analysis (SA) evaluates whether the Idaho National Laboratory (INL) Waste Associated with the Unirradiated Light Water Breeder Reactor (LWBR) waste stream (INEL167203QR1, Revision 0) is suitable for shallow land burial (SLB) at the Area 5 Radioactive Waste Management Site (RWMS) on the Nevada National Security Site (NNSS). Disposal of the INL Waste Associated with the Unirradiated LWBR waste meets all U.S. Department of Energy (DOE) Manual DOE M 435.1-1, “Radioactive Waste Management Manual,” Chapter IV, Section P performance objectives (DOE 1999). The INL Waste Associated with the Unirradiated LWBR waste stream is recommended for acceptance with the condition that the total uranium-233 (233U) inventory be limited to 2.7E13 Bq (7.2E2 Ci).

  18. Microfluidic cartridges for automated, point-of-care blood cell counting

    CSIR Research Space (South Africa)

    Smith, Suzanne

    2016-11-01

    Full Text Available cell counting to be performed. The functional steps within the microfluidic cartridge as well as the surrounding instrumentation required to control and test the cartridges in an automated fashion are described. The results recorded from 10 white blood...

  19. Intelligent image capture of cartridge cases for firearms examiners

    Science.gov (United States)

    Jones, Brett C.; Guerci, Joseph R.

    1997-02-01

    The FBI's DRUGFIRETM system is a nationwide computerized networked image database of ballistic forensic evidence. This evidence includes images of cartridge cases and bullets obtained from both crime scenes and controlled test firings of seized weapons. Currently, the system is installed in over 80 forensic labs across the country and has enjoyed a high degree of success. In this paper, we discuss some of the issues and methods associated with providing a front-end semi-automated image capture system that simultaneously satisfies the often conflicting criteria of the many human examiners visual perception versus the criteria associated with optimizing autonomous digital image correlation. Specifically, we detail the proposed processing chain of an intelligent image capture system (IICS), involving a real- time capture 'assistant,' which assesses the quality of the image under test utilizing a custom designed neural network.

  20. Research on rotary forming mechanism of cartridge bottom by FEM

    Institute of Scientific and Technical Information of China (English)

    刘钢; 姚雄亮; 黄少东; 唐全波

    2003-01-01

    The rotary forging of a cartridge bottom is simulated by finite element method with DEFORMTM. The analysis of stress and strain rate results indicates that the deformation conditions and the final geometry of a product are not completely axis-symmetrical under the partial loading conditions during the rotary forging operations. It is therefore required to have a few more rotary forging cycles at the end of total feeding to eliminate nonuniformity. The results of simulation show that the optimization of rotary forging process conditions can be achieved to avoid the underfill defect resulting from improper process conditions. This technology can be used to manufacture ring components with thin bottoms by properly controlling the working process and the tooling motion.

  1. Lift-based up-ender and methods using same to manipulate a shipping container containing unirradiated nuclear fuel

    Energy Technology Data Exchange (ETDEWEB)

    Nilles, Michael J.

    2017-08-01

    A shipping container containing an unirradiated nuclear fuel assembly is lifted off the ground by operating a crane to raise a lifting tool comprising a winch. The lifting tool is connected with the shipping container by a rigging line connecting with the shipping container at a lifting point located on the shipping container between the top and bottom of the shipping container, and by winch cabling connecting with the shipping container at the top of the shipping container. The shipping container is reoriented by operating the winch to adjust the length of the winch cabling so as to rotate the shipping container about the lifting point. Shortening the winch cabling rotates the shipping container about the lifting point from a horizontal orientation to a vertical orientation, while lengthening the winch cabling rotates the shipping container about the lifting point from the vertical orientation to the horizontal orientation.

  2. Experiment and simulation of launching process of a small-diameter steel cartridge case

    Institute of Scientific and Technical Information of China (English)

    Han-dong ZHAO; Jia-qing XIE; Zhi-peng LI; Hui-suo ZHANG

    2014-01-01

    In order to explore the rules of the deformation force during the launching of a small-diameter steel cartridge, the semi-closed bomb test method is used to test the greatest strains on chamber outer wall under the different chamber pressures. The pressure curves of cartridge chamber are measured in experiment, and the tensile test data of cartridge are loaded into the numerical calculation to compare with the experimental data. The conclusion was obtained that the calculated results match better with the experimental results by considering strain rate bilinear kinematic hardening material constitutive model. The forces on the various parts of the cartridge during launching and their deformation rules are achieved, in which the equivalent plastic strain decreases and the cylinder ring withstands the maximum equivalent stress when the cartridge case clings to the bore from the mouth to the bottom.

  3. Radiation quality-dependence of bystander effect in unirradiated fibroblasts is associated with TGF-β1-Smad2 pathway and miR-21 in irradiated keratinocytes

    Science.gov (United States)

    Yin, Xiaoming; Tian, Wenqian; Wang, Longxiao; Wang, Jingdong; Zhang, Shuyu; Cao, Jianping; Yang, Hongying

    2015-01-01

    Traditional radiation biology states that radiation causes damage only in cells traversed by ionizing radiation. But radiation-induced bystander effect (RIBE), which refers to the biological responses in unirradiated cells when the neighboring cells are exposed to radiation, challenged this old dogma and has become a new paradigm of this field. By nature, RIBEs are the consequences of intercellular communication between irradiated and unirradiated cells. However, there are still some important questions remain unanswered such as whether RIBE is dependent on radiation quality, what are the determining factors if so, etc. Using a transwell co-culture system, we found that HaCaT keratinocytes irradiated with α-particles but not X-rays could induce bystander micronucleus formation in unirradiated WS1 fibroblasts after co-culture. More importantly, the activation of TGF-β1-Smad2 pathway and the consistent decrease of miR-21 level in α-irradiated HaCaT cells were essential to the micronucleus induction in bystander WS1 cells. On the other hand, X-irradiation did not induce bystander effect in unirradiated WS1 cells, accompanied by lack of Smad2 activation and consistent decrease of miR-21 in X-irradiated HaCaT cells. Taken together, these results suggest that the radiation quality-dependence of bystander effect may be associated with the TGF-β1-Smad2 pathway and miR-21 in irradiated cells. PMID:26080011

  4. Radiation quality-dependence of bystander effect in unirradiated fibroblasts is associated with TGF-β1-Smad2 pathway and miR-21 in irradiated keratinocytes.

    Science.gov (United States)

    Yin, Xiaoming; Tian, Wenqian; Wang, Longxiao; Wang, Jingdong; Zhang, Shuyu; Cao, Jianping; Yang, Hongying

    2015-06-16

    Traditional radiation biology states that radiation causes damage only in cells traversed by ionizing radiation. But radiation-induced bystander effect (RIBE), which refers to the biological responses in unirradiated cells when the neighboring cells are exposed to radiation, challenged this old dogma and has become a new paradigm of this field. By nature, RIBEs are the consequences of intercellular communication between irradiated and unirradiated cells. However, there are still some important questions remain unanswered such as whether RIBE is dependent on radiation quality, what are the determining factors if so, etc. Using a transwell co-culture system, we found that HaCaT keratinocytes irradiated with α-particles but not X-rays could induce bystander micronucleus formation in unirradiated WS1 fibroblasts after co-culture. More importantly, the activation of TGF-β1-Smad2 pathway and the consistent decrease of miR-21 level in α-irradiated HaCaT cells were essential to the micronucleus induction in bystander WS1 cells. On the other hand, X-irradiation did not induce bystander effect in unirradiated WS1 cells, accompanied by lack of Smad2 activation and consistent decrease of miR-21 in X-irradiated HaCaT cells. Taken together, these results suggest that the radiation quality-dependence of bystander effect may be associated with the TGF-β1-Smad2 pathway and miR-21 in irradiated cells.

  5. Evaluation and comparison of a national made dental cartridge with two foreign made

    Directory of Open Access Journals (Sweden)

    Mahmood Hashemi H

    2006-06-01

    Full Text Available Background and Aim: Several factories produce dental cartridge in the world. In Iran, Daroupakhsh company is responsible for this task. The aim of this study was evaluate some properties of daroupakhsh cartridge and compare them with two imported ones: Ecocaine (made in Italy and Septodont (made in France. Materials and Methods: In this experimental study, 70 healthy patients from maxillofacial clinic of Shariaty hospital were selected. After obtaining informed consent, 0.1 cc of each carpule was injected to the patients' frontal region and the extent of anesthesia was measured at different time intervals. Also the quality of injections was evaluated by 11 surgeons. The dimensions of the three cartridges were also measured and compared together. Data were analyzed by repeated measure ANOVA and Friedman with p<0.05 as the limit of significance. Results: There was no significant difference in extent and duration of anesthesia among the studied cartridges. Surgeons were equally satisfied of all three kinds of cartridges. All of the cartridges were aspirable. Conclusion: Based on the results of this study, the three studied cartridges had similar properties.

  6. A new method for antimony speciation in plant biomass and nutrient media using anion exchange cartridge.

    Science.gov (United States)

    Tisarum, Rujira; Ren, Jing-Hua; Dong, Xiaoling; Chen, Hao; Lessl, Jason T; Ma, Lena Q

    2015-11-01

    A selective separation method based on anion exchange cartridge was developed to determine antimony (Sb) speciation in biological matrices by graphite furnace atomic absorption spectrophotometry (GFAAS). The selectivity of the cartridge towards antimonite [Sb(III)] and antimonate [Sb(V)] reversed in the presence of deionized (DI) water and 2mM citric acid. While Sb(V) was retained by the cartridge in DI water, Sb(III) was retained in citric acid media. At pH 6, Sb(III) and Sb(V) formed Sb(III)- and Sb(V)-citrate complexes, but the cartridge had higher affinity towards the Sb(III)-citrate complex. Separation of Sb(III) was tested at various concentrations in fresh and spent growth media and plant tissues. Our results showed that cartridge-based Sb speciation was successful in plant tissues, which was confirmed by HPLC-ICP-MS. The cartridge retained Sb(III) and showed 92-104% Sb(V) recovery from arsenic hyperaccumulator Pteris vittata roots treated with Sb(III) and Sb(V). The cartridge procedure is an effective alternative for Sb speciation, offering low cost, reproducible results, and simple Sb analysis using GFAAS.

  7. Scale-down prediction of industrial scale pleated membrane cartridge performance.

    Science.gov (United States)

    Brown, A I; Titchener-Hooker, N J; Lye, G J

    2011-04-01

    Flat-sheet membrane discs represent the current standard format used for experimental prediction of the scale-up of normal flow filtration processes. Use of this format is problematic, however, since the scale-down results typically show a 40-55% difference in performance compared to large-scale cartridges depending upon the feedstock used. In this work, novel pleated scale-down devices (Am=1.51-15.1×10(-3) m2) have been designed and fabricated. It is shown that these can more accurately predict the performance of industrial scale single-use pleated membrane cartridges (Am=1.06 m2) commonly used within biopharmaceutical manufacture. The single-use scale-down cartridges retain the same pleat characteristics of the larger cartridges, but require a reduced feed volume by virtue of a substantially diminished number of active membrane pleats. In this study, a 1,000-fold reduction in feed volume requirement for the scale-down cartridge with the smallest membrane area was achieved. The scale-down cartridges were tested both with clean water and a pepsin protein solution, showing flux-time relationships within 10% of the large-scale cartridge in both cases. Protein transmission levels were also in close agreement between the different scale cartridges. The similarity in performance of the scale-down and the large-scale cartridges, coupled with the low feed requirement, make such devices an excellent method by which rapid scale-up can be achieved during early stage process development for biopharmaceutical products. This new approach is a significant improvement over using flat-sheet discs as the quantitative similarity in performance with the large-scale leads to reliable scale-up predictions while requiring especially small volumes of feed material.

  8. Study of Brass Obturator Design for Combustible Cartridge Case for 105mm Tank Gun Ammunition

    Directory of Open Access Journals (Sweden)

    R.K. Syal

    1997-07-01

    Full Text Available Brass cartridge case provides rearward obturation in the tank gun ammunition where the gun systedt has a sliding breech mechanism. In the case of semi-combustible cartridge case (SCCC ammunition, obturation is provided by a smal1 metal stub. The mechanism of obturation and obturator design for kinetic energy and high explosive squash heat (HESH, SCCC ammunition of 105mm tank gun have been studied. The dynamic firing results for SCCC ammunition for 105 mm tank gun reveal height 115 mm provides perfect obturation. The ballistic performance of SCCC ammunition is comparable with that of the brass-cartridged round in the pressure range 150-450 MPa.

  9. 42 CFR 84.1157 - Chemical cartridge respirators with particulate filters; performance requirements; general.

    Science.gov (United States)

    2010-10-01

    ... APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Dust, Fume, and Mist; Pesticide; Paint Spray; Powered Air... following minimum requirements for performance and protection: (a) Breathing resistance test. (1) Resistance...) The maximum allowable resistance requirements for chemical cartridge respirators are as...

  10. Nanoparticle separation with a miniaturized asymmetrical flow field-flow fractionation cartridge

    Directory of Open Access Journals (Sweden)

    David eMüller

    2015-07-01

    Full Text Available Asymmetrical Flow Field-Flow Fractionation (AF4 is a separation technique applicable to particles over a wide size range. Despite the many advantages of AF4, its adoption in routine particle analysis is somewhat limited by the large footprint of currently available separation cartridges, extended analysis times and significant solvent consumption. To address these issues, we describe the fabrication and characterization of miniaturized AF4 cartridges. Key features of the scale-down platform include simplified cartridge and reagent handling, reduced analysis costs and higher throughput capacities. The separation performance of the miniaturized cartridge is assessed using certified gold and silver nanoparticle standards. Analysis of gold nanoparticle populations indicates shorter analysis times and increased sensitivity compared to conventional AF4 separation schemes. Moreover, nanoparticulate titanium dioxide populations exhibiting broad size distributions are analyzed in a rapid and efficient manner. Finally, the repeatability and reproducibility of the miniaturized platform are investigated with respect to analysis time and separation efficiency.

  11. Tensile and electrical properties of unirradiated and irradiated Hycon 3HP{trademark} CuNiBe

    Energy Technology Data Exchange (ETDEWEB)

    Zinkle, S.J.; Eatherly, W.S. [Oak Ridge National Lab., TN (United States)

    1996-10-01

    The unirradiated tensile properties of two different heats of Hycon 3HP{trademark} CuNiBe (HT Temper) have been measured over the temperature range of 20-500{degrees}C for longitudinal and long transverse orientations. The room temperature electrical conductivity has also been measured for both heats. Both heats exhibited a very good combination of strength and conductivity at room temperature. The strength remained relatively high at all test temperatures, with a yield strength of 420-520 MPa at 500{degrees}C. However, low levels of ductility (<5% uniform elongation) were observed at test temperatures above 200-250{degrees}C, due to flow localization adjacent to grain boundaries. Fission neutron irradiation to a dose of {approximately}0.7 dpa at temperatures between 100 and 240{degrees}C produced a slight increase in strength and a significant decrease in ductility. The measured tensile elongation increased with increasing irradiation temperature, with a uniform elongation of {approximately}3.3% observed at 240{degrees}C. The electrical conductivity decreased slightly following irradiation, due to the presence of defect clusters and Ni, Zn, Co transmutation products. The data indicate that CuNiBe alloys have irradiated tensile and electrical properties comparable or superior to CuCrZr and oxide dispersion strengthened copper at temperatures <250{degrees}C, and may be suitable for certain fusion energy structural applications.

  12. The Analysis of the General Performance and Mechanical Behavior of Unirradiated FeCrAl Alloys Before and After Welding

    Energy Technology Data Exchange (ETDEWEB)

    Gussev, Maxim N. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Field, Kevin G. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Yamamoto, Yukinori [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-06-03

    The present report summarizes and discusses the preliminary results for the in-depth characterization of the modern, nuclear-grade FeCrAl alloys currently under development. The alloys were designed for enhanced radiation tolerance and weldability, and the research is currently being pursued by the Department of Energy (DOE) Nuclear Energy Enabling Technologies (NEET) program. Last year, seven candidate FeCrAl alloys with well-controlled chemistry and microstructures were designed and produced; welding was performed under well-controlled conditions. The structure and general performance of unirradiated alloys were assessed using standardized and advanced microstructural characterization techniques and mechanical testing. The primary objective is to identify the best candidate alloy, or at a minimum to identify the contributing factors that increase the weldability and radiation tolerance of FeCrAl alloys, therefore enabling future generations of FeCrAl alloys to deliver better performance parameters. This report is structured so as to describe these critical assessments of the weldability; radiation tolerance will be reported on in later reports from this program.

  13. Disposition of Unirradiated Sodium Bonded EBR-II Driver Fuel Elements and HEU Scrap: Work Performed for FY 2007

    Energy Technology Data Exchange (ETDEWEB)

    Karen A Moore

    2007-04-01

    Specific surplus high enriched uranium (HEU) materials at the Idaho National Laboratory (INL) Materials and Fuels Complex (MFC) will be transferred to a designated off-site receiving facility. The DOE High Enriched Uranium Disposition Program Office (HDPO) will determine which materials, if any, will be prepared and transferred to an off-site facility for processing and eventual fabrication of fuel for nuclear reactors. These surplus HEU materials include approximately 7200 kg unirradiated sodium-bonded EBR-II driver fuel elements, and nearly 800 kg of HEU casting scrap from the process which formed various sodium-bonded fuels (including the EBR-II driver elements). Before the driver fuel can be packaged for shipment, the fuel elements will require removal of the sodium bond. The HEU scrap will also require repackaging in preparation for off-site transport. Preliminary work on this task was authorized by BWXT Y-12 on Nov 6, 2006 and performed in three areas: • Facility Modifications • Safety Documentation • Project Management

  14. Statistical Analysis of Firearms/Toolmarks Interpretation of Cartridge Case Evidence Using IBIS and Bayesian Networks

    Science.gov (United States)

    2015-10-24

    Cases , KB Morris, E Law, R Jefferys, & E Fabyanic, 67th AAFS Meeting, Orlando , FL, February 2015 Poster: Using likelihood ratios for source attribution...of Glock™ model 21 fired cartridge cases , C Hefner, & KB Morris, 67th AAFS Meeting, Orlando , FL, February 2015. (c) Presentations Number of...and known cartridge cases ) to assess the performance of the Bayesian networks created during the study . In all cases the sets were submitted in a

  15. Evaluation and comparison of a national made dental cartridge with two foreign made

    OpenAIRE

    2006-01-01

    Background and Aim: Several factories produce dental cartridge in the world. In Iran, Daroupakhsh company is responsible for this task. The aim of this study was evaluate some properties of daroupakhsh cartridge and compare them with two imported ones: Ecocaine (made in Italy) and Septodont (made in France). Materials and Methods: In this experimental study, 70 healthy patients from maxillofacial clinic of Shariaty hospital were selected. After obtaining informed consent, 0.1 cc of each carpu...

  16. The indicating FTA elute cartridge a solid sample carrier to detect high-risk HPV and high-grade cervical lesions

    NARCIS (Netherlands)

    Bie, R.P. de; Schmeink, C.E.; Bakkers, J.M.J.E.; Snijders, P.J.L.M.; Quint, W.G.V.; Massuger, L.F.A.G.; Bekkers, R.L.M.; Melchers, W.J.G.

    2011-01-01

    The clinically validated high-risk human papillomavirus (hrHPV) Hybrid Capture 2 (HC2) and GP5+/6+-PCR assays were analyzed on an Indicating FTA Elute cartridge (FTA cartridge). The FTA cartridge is a solid dry carrier that allows safe transport of cervical samples. FTA cartridge samples were

  17. The influence of late-stage pupal irradiation and increased irradiated: un-irradiated male ratio on mating competitiveness of the malaria mosquito Anopheles arabiensis Patton.

    Science.gov (United States)

    Helinski, M E H; Knols, B G J

    2009-06-01

    Competitiveness of released males in genetic control programmes is of critical importance. In this paper, we explored two scenarios to compensate for the loss of mating competitiveness after pupal stage irradiation in males of the malaria mosquito Anopheles arabiensis. First, competition experiments with a higher ratio of irradiated versus un-irradiated males were performed. Second, pupae were irradiated just prior to emergence and male mating competitiveness was determined. Males were irradiated in the pupal stage with a partially or fully-sterilizing dose of 70 or 120 Gy, respectively. Pupae were irradiated aged 20-26 h (young) as routinely performed, or the pupal stage was artificially prolonged by cooling and pupae were irradiated aged 42-48 h (old). Irradiated males competed at a ratio of 3:1:1 to un-irradiated males for mates in a large cage design. At the 3:1 ratio, the number of females inseminated by males irradiated with 70 Gy as young pupae was similar to the number inseminated by un-irradiated males for the majority of the replicates. At 120 Gy, significantly fewer females were inseminated by irradiated than by un-irradiated males. The irradiation of older pupae did not result in a significantly improved male mating competitiveness compared to the irradiation of young pupae. Our findings indicate that the loss of competitiveness after pupal stage irradiation can be compensated for by a threefold increase of irradiated males, but only for the partially-sterilizing dose. In addition, cooling might be a useful tool to facilitate handling processes of large numbers of mosquitoes in genetic control programmes.

  18. Cell cycle tracking for irradiated and unirradiated bystander cells in a single colony with exposure to a soft X-ray microbeam.

    Science.gov (United States)

    Kaminaga, Kiichi; Noguchi, Miho; Narita, Ayumi; Hattori, Yuya; Usami, Noriko; Yokoya, Akinari

    2016-11-01

    To establish a new experimental technique to explore the photoelectric and subsequent Auger effects on the cell cycles of soft X-ray microbeam-irradiated cells and unirradiated bystander cells in a single colony. Several cells located in the center of a microcolony of HeLa-Fucci cells consisting of 20-80 cells were irradiated with soft X-ray (5.35 keV) microbeam using synchrotron radiation as a light source. All cells in the colony were tracked for 72 h by time-lapse microscopy imaging. Cell cycle progression, division, and death of each cell in the movies obtained were analyzed by pedigree assay. The number of cell divisions in the microcolony was also determined. The fates of these cells were clarified by tracking both irradiated and unirradiated bystander cells. Irradiated cells showed significant cell cycle retardation, explosive cell death, or cell fusion after a few divisions. These serious effects were also observed in 15 and 26% of the bystander cells for 10 and 20 Gy irradiation, respectively, and frequently appeared in at least two daughter or granddaughter cells from a single-parent cell. We successfully tracked the fates of microbeam-irradiated cells and unirradiated bystander cells with live cell recordings, which have revealed the dynamics of soft X-ray irradiated and unirradiated bystander cells for the first time. Notably, cell deaths or cell cycle arrests frequently arose in closely related cells. These details would not have been revealed by a conventional immunostaining imaging method. Our approach promises to reveal the dynamic cellular effects of soft X-ray microbeam irradiation and subsequent Auger processes from various endpoints in future studies.

  19. Revised ANL-reported tensile data for unirradiated and irradiated (FFTF, HFIR) V-Ti and V-Cr-Ti alloys

    Energy Technology Data Exchange (ETDEWEB)

    Billone, M.C. [Argonne National Lab., IL (United States)

    1998-03-01

    The tensile data for all unirradiated and irradiated vanadium alloys samples tested at Argonne National Laboratory (ANL) have been critically reviewed and, when necessary, revised. The review and revision are based on reanalyzing the original load-displacement strip chart recordings by a methodology consistent with current ASTM standards. For unirradiated alloys (162 samples), the revised values differ from the previous values as follows: {minus}11{+-}19 MPa ({minus}4{+-}6%) for yield strength (YS), {minus}3{+-}15 MPa ({minus}1{+-}3%) for ultimate tensile strength (UTS), {minus}5{+-}2% strain for uniform elongation (UE), and {minus}4{+-}2% strain for total elongation (TE). Of these changes, the decrease in {minus}1{+-}6 MPa (0{+-}1%) for UTS, {minus}5{+-}2% for UE, and {minus}4{+-}2% for TE. Of these changes, the decrease in UE values for alloys irradiated and tested at 400--435 C is the most significant. This decrease results from the proper subtraction of nongauge-length deformation from measured crosshead deformation. In previous analysis of the tensile curves, the nongauge-length deformation was not correctly determined and subtracted from the crosshead displacement. The previously reported and revised tensile values for unirradiated alloys (20--700 C) are tabulated in Appendix A. The revised tensile values for the FFTF-irradiated (400--600 C) and HFIR-irradiated (400 C) alloys are tabulated in Appendix B, along with the neutron damage and helium levels. Appendix C compares the revised values to the previously reported values for irradiated alloys. Appendix D contains previous and revised values for the tensile properties of unirradiated V-5Cr-5Ti (BL-63) alloy exposed to oxygen.

  20. Oxidative dissolution of unirradiated Mimas MOX fuel (U/Pu oxides) in carbonated water under oxic and anoxic conditions

    Science.gov (United States)

    Odorowski, Mélina; Jégou, Christophe; De Windt, Laurent; Broudic, Véronique; Peuget, Sylvain; Magnin, Magali; Tribet, Magaly; Martin, Christelle

    2016-01-01

    Few studies exist concerning the alteration of Mimas Mixed-OXide (MOX) fuel, a mixed plutonium and uranium oxide, and data is needed to better understand its behavior under leaching, especially for radioactive waste disposal. In this study, two leaching experiments were conducted on unirradiated MOX fuel with a strong alpha activity (1.3 × 109 Bq.gMOX-1 reproducing the alpha activity of spent MOX fuel with a burnup of 47 GWd·tHM-1 after 60 years of decay), one under air (oxic conditions) for 5 months and the other under argon (anoxic conditions with [O2] MOX pellets under both oxic and anoxic conditions were similar, demonstrating the predominant effect of alpha radiolysis on the oxidative dissolution of the pellets. The uranium released was found to be mostly in solution as carbonate species according to modeling, whereas the Am and Pu released were significantly sorbed or precipitated onto the TiO2 reactor. An intermediate fraction of Am (12%) was also present as colloids. SEM and EPMA results indicated a preferential dissolution of the UO2 matrix compared to the Pu-enriched agglomerates, and Raman spectroscopy showed the Pu-enriched agglomerates were slightly oxidized during leaching. Unlike Pu-enriched zones, the UO2 grains were much more sensitive to oxidative dissolution, but the presence of carbonates did not enable observation of an oxidized layer by Raman spectroscopy with the exception of a few areas revealing the presence of U4O9. This data shows the heterogeneous nature of the alteration and the need to combine information from different techniques to determine the origin of releases.

  1. A cartridge based sensor array platform for multiple coagulation measurements from plasma.

    Science.gov (United States)

    Cakmak, O; Ermek, E; Kilinc, N; Bulut, S; Baris, I; Kavakli, I H; Yaralioglu, G G; Urey, Hakan

    2015-01-07

    This paper proposes a MEMS-based sensor array enabling multiple clot-time tests for plasma in one disposable microfluidic cartridge. The versatile LoC (Lab-on-Chip) platform technology is demonstrated here for real-time coagulation tests (activated Partial Thromboplastin Time (aPTT) and Prothrombin Time (PT)). The system has a reader unit and a disposable cartridge. The reader has no electrical connections to the cartridge. This enables simple and low-cost cartridge designs and avoids reliability problems associated with electrical connections. The cartridge consists of microfluidic channels and MEMS microcantilevers placed in each channel. The microcantilevers are made of electroplated nickel. They are actuated remotely using an external electro-coil and the read-out is also conducted remotely using a laser. The phase difference between the cantilever oscillation and the coil drive is monitored in real time. During coagulation, the viscosity of the blood plasma increases resulting in a change in the phase read-out. The proposed assay was tested on human and control plasma samples for PT and aPTT measurements. PT and aPTT measurements from control plasma samples are comparable with the manufacturer's datasheet and the commercial reference device. The measurement system has an overall 7.28% and 6.33% CV for PT and aPTT, respectively. For further implementation, the microfluidic channels of the cartridge were functionalized for PT and aPTT tests by drying specific reagents in each channel. Since simultaneous PT and aPTT measurements are needed in order to properly evaluate the coagulation system, one of the most prominent features of the proposed assay is enabling parallel measurement of different coagulation parameters. Additionally, the design of the cartridge and the read-out system as well as the obtained reproducible results with 10 μl of the plasma samples suggest an opportunity for a possible point-of-care application.

  2. 3D-printed paper spray ionization cartridge with fast wetting and continuous solvent supply features.

    Science.gov (United States)

    Salentijn, Gert I J; Permentier, Hjalmar P; Verpoorte, Elisabeth

    2014-12-02

    We report the development of a 3D-printed cartridge for paper spray ionization (PSI) that can be used almost immediately after solvent introduction in a dedicated reservoir and allows prolonged spray generation from a paper tip. The fast wetting feature described in this work is based on capillary action through paper and movement of fluid between paper and the cartridge material (polylactic acid, PLA). The influence of solvent composition, PLA conditioning of the cartridge with isopropanol, and solvent volume introduced into the reservoir have been investigated with relation to wetting time and the amount of solvent consumed for wetting. Spray has been demonstrated with this cartridge for tens of minutes, without any external pumping. It is shown that fast wetting and spray generation can easily be achieved using a number of solvent mixtures commonly used for PSI. The PSI cartridge was applied to the analysis of lidocaine from a paper tip using different solvent mixtures, and to the analysis of lidocaine from a serum sample. Finally, a demonstration of online paper chromatography-mass spectrometry is given.

  3. Special Analysis for the Disposal of the Idaho National Laboratory Unirradiated Light Water Breeder Reactor Rods and Pellets Waste Stream at the Area 5 Radioactive Waste Management Site, Nevada National Security Site, Nye County, Nevada

    Energy Technology Data Exchange (ETDEWEB)

    Shott, Gregory [NSTec

    2014-08-31

    The purpose of this special analysis (SA) is to determine if the Idaho National Laboratory (INL) Unirradiated Light Water Breeder Reactor (LWBR) Rods and Pellets waste stream (INEL103597TR2, Revision 2) is suitable for disposal by shallow land burial (SLB) at the Area 5 Radioactive Waste Management Site (RWMS). The INL Unirradiated LWBR Rods and Pellets waste stream consists of 24 containers with unirradiated fabricated rods and pellets composed of uranium oxide (UO2) and thorium oxide (ThO2) fuel in zirconium cladding. The INL Unirradiated LWBR Rods and Pellets waste stream requires an SA because the 229Th, 230Th, 232U, 233U, and 234U activity concentrations exceed the Nevada National Security Site (NNSS) Waste Acceptance Criteria (WAC) Action Levels.

  4. About the mechanisms governing the hydrogen effect on visco plasticity of unirradiated fully annealed zircaloy-4 sheet

    Energy Technology Data Exchange (ETDEWEB)

    Rupa, N [Electricite de France (EDF), Nuclear Power Div., Lab. Group, 93 - Saint-Denis (France); Clavel, M. [Universite de Technologie de Compiegne, Centre de Recherches de Royalliu, 60 (France); Bouffioux, P.; Domain, C. [Electricite de France, Research engineer, RD Div., Material Study Branch, 77 - Moret sur Loing (France); Legris, A. [Lille-1 Univ., UMR 8517, 59 - Villeneuve-d' Ascq (France)

    2002-07-01

    It has been observed that hydrogen either in solid solution or precipitated under the form of hydrides has an impact on the visco-plasticity of CWSR Zircaloy-4 cladding tubes, increasing significantly the creep resistance. The use of TEM on the structurally complex CWSR material being unlikely to identify the deformation mechanisms, it has been decided to complete this R and D program on recrystallized material. A study has been carried out on fully annealed unirradiated Zircaloy-4 sheet used for the manufacturing of the fuel subassembly grids. Mechanical tests were performed for large ranges of temperatures (300 to 400 deg C), stresses (120 to 250 MPa), and strain rates (2 x 10{sup -7} to 2 x 10{sup -3} s{sup -1}) on as-received and hydrided specimen. The results emphasize: - Hydrogen in solid solution induces a softening of the material. The TEM observations have revealed identical structure of dislocations for both as-received and hydrided specimens. The softening has been particularly observed when dynamic strain aging is activated. It is assumed that atomic hydrogen decreases the dislocation pinning caused by interstitial and/or enhances the intrinsic mobility of the dislocations. With respect to ab initio calculation, atomic hydrogen might be trapped easily by the core of the dislocation, this phenomenon contributing to decrease the lattice friction and to enhance planar glide. - Precipitated hydrides induce a hardening of the material as observed for CWSR Zircaloy 4. The magnitude of the phenomenon depends upon temperature and stress. An analysis of the unload sequences for tension tests and of the secondary strain rates for creep tests leads to the conclusion that hydrides change the kinematics hardening by increasing the internal stress with respect to the as-received material. TEM observation combined with this visco-plasticity approach has revealed that: first, as long as the internal stress is increasing versus plastic strain, hydride are obstacles to

  5. Fatalities caused by spherical bullets fired from blank cartridge guns in Istanbul, Turkey.

    Science.gov (United States)

    Uzün, Ibrahim; Büyük, Yalçin; Erkol, Zerrin; Ağritmiş, Hasan; Kir, Ziya

    2009-09-01

    Blank cartridge guns are generally regarded as being harmless and are not considered to be firearms in the legal sense in most countries. To show the danger of these guns upon simple modifications, we report 59 fatalities resulting from these simply modified blank cartridge guns in Istanbul, Turkey. The great majority of the victims were males and the age of those ranged from 11 to 61 years. In 55.9% of these cases, homicide was the origin followed by suicide (39%). The right temporal region was detected to be the preferred region in suicidal shots by blank cartridge guns with a frequency of 56.5%. In trial shots, all these guns were detected to discharge steel or lead spherical objects, generally 4 or 5 mm in diameter, successfully. Our findings strongly suggest that these guns should also be considered as handguns in the legal sense.

  6. A new coal distribution system for general industry: the coal cartridge system

    Energy Technology Data Exchange (ETDEWEB)

    Katoh, S.

    1986-01-01

    The author introduces the concept of a coal cartridge system (CCS) for the distribution of coal, outlines the flow of coal from coal centre to end user, explains distribution diagrams, and compares CCS combustion with the combustion system used in stoker boilers. Various problems being encountered in the development of practical coal cartridge systems are discussed. Finally, details are given of demonstration tests being carried out in connection with the supply terminal and boiler plant aspects of CCS (at the Tokuyama and Iwakuni Laboratories, respectively). 11 figs., 2 tabs.

  7. The two-fire, one-cartridge stapling method using a modified Endo-GIA.

    Science.gov (United States)

    Yamaguchi, A; Tsuchida, M

    1996-08-01

    The endoscopic stapler (Endo-GIA) was designed to divide tissue between two triple-stapled lines. The endoscopic surgeon frequently encounters situations where only stapling is required. Kirby described a staple closure method that uses a knifeless Endo-GIA cartridge. This method, although useful, has the problem of the modified Endo-GIA unit locking. Therefore, we devised a new technique for endoscopic stapling that involves two consecutive staplings using one cartridge without cutting. This method requires modification of the Endo-GIA system by removing the safety-lock system. In addition to enabling endoscopic stapling techniques without the risk of locking, the method can effect a significant cost savings.

  8. 3D-printed paper spray ionization cartridge with fast wetting and continuous solvent supply features

    NARCIS (Netherlands)

    Salentijn, Gert I J; Permentier, Hjalmar P; Verpoorte, Elisabeth

    2014-01-01

    We report the development of a 3D-printed cartridge for paper spray ionization (PSI) that can be used almost immediately after solvent introduction in a dedicated reservoir and allows prolonged spray generation from a paper tip. The fast wetting feature described in this work is based on capillary a

  9. CONCENTRATION AND PROCESSING OF WATERBORNE VIRUSES BY POSITIVE CHARGE 1MDS CARTRIDGE FILTERS AND ORGANIC FLOCCULATION

    Science.gov (United States)

    This chapter describes the most widely used virus adsorption-elution (VIRADEL) method for recovering human enteric viruses from water matrices (Fout et al., 1996). The method takes advantage of postively charged cartridge filters to concentrate viruses from water. The major adv...

  10. Demonstration of Metastable Intermolecular Composites (MIC) on Small Caliber Cartridges and CAD/PAD Percussion Primers

    Science.gov (United States)

    2009-07-01

    of the output charge. In fact, the improved ignition pushed ten of the MIC-primed cartridges over the high pressure limit, whereas, only two of the...nls (lat) uso OOiy) Box Label lnfomalion wee FIP #41 Machine# 18 Date fl/19/2007 Caliber 5.56 Ammo Lot# BLH07D12().005 - -- Bullet Mfg Siorra Gr. Wt

  11. Small-Caliber Ammunition Identification Guide. Volume 1. Small-Arms Cartridges Up to 15 mm

    Science.gov (United States)

    1978-06-01

    strands. In 1914, - : ... . the bullet shape was changed to a long, pointed, jacketed bullet with ant aluminum (or fiber) nose 1,,: filler ahead of the...KINGDOM ROMANIA "Made at R.O.F. plant at On 7.6209-mm cartridges. Woolwich, London. 1963-1969. 񓞰-1949. Sec Note 3. .𔃻’.~ A•SO A356 O UNITUD

  12. Development of a Paper Spray Mass Spectrometry Cartridge with Integrated Solid Phase Extraction for Bioanalysis.

    Science.gov (United States)

    Zhang, Chengsen; Manicke, Nicholas E

    2015-06-16

    A novel paper spray cartridge with an integrated solid phase extraction (SPE) column is described. The cartridge performs extraction and pre-concentration, as well as sample ionization by paper spray, from complex samples such as plasma. The cartridge allows for selective enrichment of target molecules from larger sample volumes and removal of the matrix, which significantly improved the signal intensity of target compounds in plasma samples by paper spray ionization. Detection limits, quantitative performance, recovery, ionization suppression, and the effects of sample volume were evaluated for five drugs: carbamazepine, atenolol, sulfamethazine, diazepam, and alprazolam. Compared with direct paper spray analysis of dried plasma spots, paper spray analysis using the integrated solid phase extraction improved the detection limits significantly by a factor of 14-70, depending on the drug. The improvement in detection limits was, in large part, due to the capability of analyzing larger sample volumes. In addition, ionization suppression was found to be lower and recovery was higher for paper spray with integrated SPE, as compared to direct paper spray analysis. By spiking an isotopically labeled internal standard into the plasma sample, a linear calibration curve for the drugs was obtained from the limit of detection (LOD) to 1 μg/mL, indicating that this method can be used for quantitative analysis. The paper spray cartridge with integrated SPE could prove valuable for analytes that ionize poorly, in applications where lower detection limits are required, or on portable mass spectrometers. The improved performance comes at the cost of requiring a more complex paper spray cartridge and requiring larger sample volumes than those used in typical direct paper spray ionization.

  13. Irradiation programme MANITU: Results of pre-examinations and Charpy tests with unirradiated materials; Bestrahlungsprogramm MANITU. Ergebnisse der Voruntersuchungen und der Kerbschlagbiegeversuche mit den unbestrahlten Werkstoffen

    Energy Technology Data Exchange (ETDEWEB)

    Rieth, M.; Dafferner, B.; Ries, H.; Romer, O.

    1995-04-01

    The irradiation project MANITU was planned in the frame of the European Long-term Fusion Materials Development Programme. The results of MANITU will have a lasting influence on the future actions within the materials development programme. The problem of the irradiation induced embrittlement of possible martensitic alloy candidates is still unsolved. But after the evaluation of sub-size Charpy tests with the unirradiated refrence specimens of MANITU a first tendency is recognizable. The Charpy properties of the newly developed low activation 7-10% Cr-WVTa alloys are clearly better compared with the modified commerical 10-11% Cr-NiMoVNb steels. In the present report the pre-examinations are documented and the Charpy test results with unirradiated reference specimens are analysed and assessed. (orig.) [Deutsch] Das Bestrahlungsprojekt MANITU wurde im Rahmen des europaeischen Langzeitprogramms fuer Materialentwicklung fuer die Kernfusion geplant. Die daraus gewonnenen Ergebnisse werden das weitere Vorgehen bei der Materialentwicklung entscheidend beeinflussen. Das Problem der bestrahlungsinduzierten Versproedung bei den in Frage kommenden martensitischen Werkstoffen ist nach wie vor ungeloest. Eine erste Tendenz zeichnet sich nach der Auswertung der Kerbschlagbiegeversuche an den unbestrahlten miniaturisierten Referenzproben des MANITU-Programms ab. Die neu entwickelten niedrig aktivierbaren 7-10% Cr-WVTa-Legierungen weisen gegenueber den modifizierten kommerziellen 10-11% Cr-NiMoVNb-Staehlen deutlich bessere Kerbschlageigenschaften auf. Im vorliegenden Bericht werden die Voruntersuchungen dokumentiert und die Ergebnisse aus den Kerbschlagbiegeversuchen der unbestrahlten Referenzproben analysiert und bewertet. (orig.)

  14. Preparation of imprinted cryogel cartridge for chiral separation of l-phenylalanine.

    Science.gov (United States)

    Akgönüllü, Semra; Yavuz, Handan; Denizli, Adil

    2017-06-01

    l-Phe-imprinted cryogel cartridge was prepared for the chiral separation of l-Phe. N-Methacryloyl l-phenylalanine (MAPA) was used as a functional monomer for complexing with l-Phe. The selectivity of the membranes was investigated by using d-Phe, l-Trp, and d-Trp as competitor molecules. The PHEMAPA-l-Trp membranes were 6.4, 4.3, and 5.5 times more selective for l-Phe than d-Phe, l-Trp, and d-Trp, respectively. The PHEMAPA-l-Phe cryogel cartridge was incorporated into the fast protein liquid chromatography (FPLC) equipment and was able to separate D,l-Phe racemic mixture efficiently. The PHEMAPA-l-Phe membranes were shown to be reusable many times without significant loss of the adsorption capacity.

  15. Purification of Astaxanthin from Laminariajaponica by Ionic Liquid-based Monolithic Cartridge

    Institute of Scientific and Technical Information of China (English)

    YOON Chang-hwan; ZHU Tao; ROW Kyung-ho

    2012-01-01

    An effective and accurate method was developed for the extraction of astaxanthin from Laminariajaponica with subsequent separation by ionic liquid-based monolithic cartridge.The optimized extraction conditions including extraction solvent(ethanol),extraction time(90 min) and ultrasonic power(75 W) were obtained by systematical investigation.Chromatographic analysis was performed on a C18 column with ultraviolet(UV) detection at 476nm,and a solution consisting of methanol/acetonitrile/H20/dichloromethane(83:6:6:5,volume ratio) was used as the mobile phase at a flow rate of 0.7 mL/min.After ionic liquid-based monolithic solid phase extraction,17.82 μg/g astaxanthin was obtained from Laminariajaponica.This ionic liquid-based monolithic cartridge exhibits high affinity and selectivity for astaxanthin,and it can be potentially used as the stationary phase of high performance liquid chromatography( HPLC).

  16. Using the PL/SQL Cartridge of the Oracle Application Server to Deploy Web Applications

    Energy Technology Data Exchange (ETDEWEB)

    Begovich, C.L.

    1999-06-14

    Deploying business applications on the internal Web is a priority at Oak Ridge National Laboratory (Lockheed Martin Energy Research) and Lockheed Martin Energy Systems, Inc. as with most corporations. Three separate applications chose the Oracle Application Server (OAS), using the PL/SQL cartridge as a Web deployment method. This method was chosen primarily because the data was already stored in Oracle tables and developers knew HJSQL or at least SQL. The Database Support group had the responsibility of installing, testing, and determining standard methods for interfacing with the PL/SQL cartridge of the OAS. Note that the term Web Application Server was used for version 3, but in this discussion, OAS will be used for both version 3 and version 4.

  17. Determination of 137Cs in large volume seawater using Cu-hexacyanoferrate cartridge filters

    Science.gov (United States)

    Visetpotjanakit, S.; Tumnoi, Y.

    2017-06-01

    A simple method to determine 137Cs in seawater has been developed based on the use of a Cu-hexacyanoferrate scavenger. The Cu-hexacyanoferrate supported on cotton wound cartridge filter was used to absorb 137Cs from seawater by passing large volumes over the cartridge filters with flowrate of 240 L hr-1. Results from the Cu-hexacyanoferrate method were proved acceptable for accuracy with bias below ± 20 % i.e. - 9.16 to + 18.55 % when compared with the traditional ammonium molybdophosphate pre-concentration method. This developed method is cost-effective and less time consuming. In addition it can be easily performed at sampling fields.

  18. Continuous-flow multi-analyte biosensor cartridge with controllable linear response range.

    Science.gov (United States)

    Frey, Olivier; Talaei, Sara; van der Wal, Peter D; Koudelka-Hep, Milena; de Rooij, Nico F

    2010-09-01

    This article presents the design and fabrication of a microfluidic biosensor cartridge for the continuous and simultaneous measurement of biologically relevant analytes in a sample solution. The biosensor principle is based on the amperometric detection of hydrogen peroxide using enzyme-modified electrodes. The low-integrated and disposable cartridge is fabricated in PDMS and SU-8 by rapid prototyping. The device is designed in such a way that it addresses two major challenges of biosensors using microfluidics approaches. Firstly, the enzymatic membrane is deposited on top of the platinum electrodes via a microfluidic deposition channel from outside the cartridge. This decouples the membrane deposition from the cartridge fabrication and enables the user to decide when and with what mixture he wants to modify the electrode. Secondly, by using laminar sheath-flow of the sample and a buffer solution, a dynamic diffusion layer is created. The analyte has to diffuse through the buffer solution layer before it can reach the immobilized enzyme membrane on the electrode. Controlling of the thickness of the diffusion layer by variation of the flow-rate of the two layers enables the user to adjust the sensitivity and the linear region of the sensor. The point where the buffer and sample stream join proved critical in creating the laminar sheath-flow. Results of computational simulations considering fluid dynamics and diffusion are presented. The consistency of the device was investigated through detection of glucose and lactate and are in accordance with the CFD simulations. A sensitivity of 157+/-28 nA/mM for the glucose sensor and 79+/-12 nA/mM for the lactate sensor was obtained. The linear response range of these biosensors could be increased from initially 2 mM up to 15 mM with a limit of detection of 0.2 mM.

  19. Pulverized-coal-firing small-size boiler for coal-cartridge system

    Energy Technology Data Exchange (ETDEWEB)

    1986-12-01

    Kawasaki Heavy Industries, Ltd. supplied a test boiler plant to the Iwakuni Experimental Station of the Coal Cartridge System (CCS) Promotion Association in September 1985; this was the first pulverized-coal-fired small industrial boiler in Japan. Tests will be performed for two years, until fiscal 1987, at the CCS Iwakuni Experimental Station to establish a method of coal-firing with a performance comparable to heavy oil firing. The boiler plant has been operating satisfactorily.

  20. Cartridge Casing Catcher With Reduced Firearm Ejection Port Flash and Noise

    Science.gov (United States)

    2009-05-26

    respective deflectors. The magnetic material is generally at least one of steel, Strontium and Barium ferrite , Samarium- Cobalt , Neody- mium -Iron...Boron, and Aluminum-Nickel- Cobalt alloy. Accordingly, the present invention may provide a cartridge casing catcher with reduced firearm ejection port...a Strontium and Barium ferrite , Samarium-Co- balt, Neodymium-Iron-Boron, other pennanently magnetic rare earth alloys, and Alnico (i.e., Aluminum

  1. End of Service Life Indicator (ESLI) for Respirator Cartridges. Part 1: Literature Review

    Science.gov (United States)

    2005-07-01

    containing a relatively simple fibre optic chemical sensor (FOCS) for indicating the end of service life of the unit. The indicator concept design...light intensity passing to the detector decreased. Figure 28: Fibre optic containing a microporous glass section (surface area ~250m2/g) [95...Figure 29: Fibre optic chemical sensor (FOCS) for respirator cartridge (A) FOCS with light source and detector (B) electronic module connected

  2. Hollow-Fiber Cartridges: Model Systems for Virus Removal from Blood

    Science.gov (United States)

    Jacobitz, Frank; Menon, Jeevan

    2005-11-01

    Aethlon Medical is developing a hollow-fiber hemodialysis device designed to remove viruses and toxins from blood. Possible target viruses include HIV and pox-viruses. The filter could reduce virus and viral toxin concentration in the patient's blood, delaying illness so the patient's immune system can fight off the virus. In order to optimize the design of such a filter, the fluid mechanics of the device is both modeled analytically and investigated experimentally. The flow configuration of the proposed device is that of Starling flow. Polysulfone hollow-fiber dialysis cartridges were used. The cartridges are charged with water as a model fluid for blood and fluorescent latex beads are used in the experiments as a model for viruses. In the experiments, properties of the flow through the cartridge are determined through pressure and volume flow rate measurements of water. The removal of latex beads, which are captured in the porous walls of the fibers, was measured spectrophotometrically. Experimentally derived coefficients derived from these experiments are used in the analytical model of the flow and removal predictions from the model are compared to those obtained from the experiments.

  3. Behavioral response and pain perception to computer controlled local anesthetic delivery system and cartridge syringe.

    Science.gov (United States)

    Yogesh Kumar, T D; John, J Baby; Asokan, Sharath; Geetha Priya, P R; Punithavathy, R; Praburajan, V

    2015-01-01

    The present study evaluated and compared the pain perception, behavioral response, physiological parameters, and the role of topical anesthetic administration during local anesthetic administration with cartridge syringe and computer controlled local anesthetic delivery system (CCLAD). A randomized controlled crossover study was carried out with 120 children aged 7-11 years. They were randomly divided into Group A: Receiving injection with CCLAD during first visit; Group B: Receiving injection with cartridge syringe during first visit. They were further subdivided into three subgroups based on the topical application used: (a) 20% benzocaine; (b) pressure with cotton applicator; (c) no topical application. Pulse rate and blood pressure were recorded before and during injection procedure. Objective evaluation of disruptive behavior and subjective evaluation of pain were done using face legs activity cry consolability scale and modified facial image scale, respectively. The washout period between the two visits was 1-week. Injections with CCLAD produced significantly lesser pain response, disruptive behavior (P < 0.001), and pulse rate (P < 0.05) when compared to cartridge syringe injections. Application of benzocaine produced lesser pain response and disruptive behavior when compared to the other two subgroups, although the result was not significant. Usage of techniques which enhance behavioral response in children like injections with CCLAD can be considered as a possible step toward achieving a pain-free pediatric dental practice.

  4. Removal of Cryptosporidium and polystyrene microspheres from swimming pool water with sand, cartridge, and precoat filters.

    Science.gov (United States)

    Amburgey, James E; Walsh, Kimberly J; Fielding, Roy R; Arrowood, Michael J

    2012-03-01

    Cryptosporidium has caused the majority of waterborne disease outbreaks in treated recreational water venues in the USA for many years running. This research project evaluated some common US swimming pool filters for removing Cryptosporidium oocysts, 5-µm diameter polystyrene microspheres, and 1-µm diameter polystyrene microspheres. A 946 L hot tub with interchangeable sand, cartridge, and precoat filters was used at room temperature for this research. Simulated pool water for each experiment was created from Charlotte, NC (USA) tap water supplemented with alkalinity, hardness, chlorine, and a mixture of artificial sweat and urine. Precoat (i.e., diatomaceous earth and perlite) filters demonstrated pathogen removal efficiencies of 2.3 to 4.4 log (or 99.4-99.996%). However, sand and cartridge filters had average Cryptosporidium removals of 0.19 log (36%) or less. The combined low filter removal efficiencies of sand and cartridge filters along with the chlorine-resistant properties of Cryptosporidium oocysts could indicate a regulatory gap warranting further attention and having significant implications on the protection of public health in recreational water facilities. The 5-µm microspheres were a good surrogate for Cryptosporidium oocysts in this study and hold promise for use in future research projects, field trials, and/or product testing on swimming pool filters.

  5. Behavioral response and pain perception to computer controlled local anesthetic delivery system and cartridge syringe

    Directory of Open Access Journals (Sweden)

    T D Yogesh Kumar

    2015-01-01

    Full Text Available Aim: The present study evaluated and compared the pain perception, behavioral response, physiological parameters, and the role of topical anesthetic administration during local anesthetic administration with cartridge syringe and computer controlled local anesthetic delivery system (CCLAD. Design: A randomized controlled crossover study was carried out with 120 children aged 7-11 years. They were randomly divided into Group A: Receiving injection with CCLAD during first visit; Group B: Receiving injection with cartridge syringe during first visit. They were further subdivided into three subgroups based on the topical application used: (a 20% benzocaine; (b pressure with cotton applicator; (c no topical application. Pulse rate and blood pressure were recorded before and during injection procedure. Objective evaluation of disruptive behavior and subjective evaluation of pain were done using face legs activity cry consolability scale and modified facial image scale, respectively. The washout period between the two visits was 1-week. Results: Injections with CCLAD produced significantly lesser pain response, disruptive behavior (P < 0.001, and pulse rate (P < 0.05 when compared to cartridge syringe injections. Application of benzocaine produced lesser pain response and disruptive behavior when compared to the other two subgroups, although the result was not significant. Conclusion: Usage of techniques which enhance behavioral response in children like injections with CCLAD can be considered as a possible step toward achieving a pain-free pediatric dental practice.

  6. Is the exploding powder gas of the propellant from blank cartridges sterile?

    Science.gov (United States)

    Rothschild, M A; Liesenfeld, O

    1996-11-11

    Shots from blank weapons loaded with blank cartridges, when fired from close range or as a contact shot, almost always cause the skin to burst open and lead to injuries to structures below the surface. Subsequently, wound infections are often observed. In addition to the introduction of skin germs, the possibility exists that contaminated propellants may enter into consideration as a source of infection. Using step-by-step experimental procedures we were able to demonstrate that: 1. Blank cartridge propellants were almost always contaminated with Bacillus cereus (nitrocellulose powder more so than black powder); 2. When the shot is fired numerous bacteria survive and are forced out with the gunsmoke from the weapon and thus find their way into the wound. In principle, blank cartridge propellant thus exhibits as much potential for wound infection as the skin germs. Clearly, the species B. cereus is prominent in this context. For open injuries even with 'harmless' blank weapons, an antibiotic prophylaxis should always be administered.

  7. Reagent-loaded cartridges for valveless and automated fluid delivery in microfluidic devices.

    Science.gov (United States)

    Linder, Vincent; Sia, Samuel K; Whitesides, George M

    2005-01-01

    An important problem in the life sciences and in health care is simple and rapid detection of biomarkers. Although microfluidic devices are potentially useful in addressing this problem, current techniques for automating fluid delivery--which include valves and electroosmosis--require sophisticated microfabrication of the chip, bulky instrumentation, or both. In this paper, we describe a simple and reliable technique for storing and delivering a sequence of reagents to a microfluidic device. The technique is low-cost, requires minimal user intervention, and can be performed in resource-poor settings (e.g., outside of a laboratory) in the absence of electricity and computer-controlled equipment. In this method, cartridges made of commercially available tubing are filled by sequentially injecting plugs of reagents separated by air spacers. The air spacers prevent the reagents from mixing with each other during cartridge preparation, storage, and usage. As an example, we used this "plug-in cartridge" technology to complete a solid-phase immunoassay in a microchannel in 2 min with low-nanomolar sensitivity and demonstrate the diagnosis of HIV in 13 min.

  8. 废弃硒鼓资源化技术研究%Processing of Waste Toner Cartridge Recycling

    Institute of Scientific and Technical Information of China (English)

    黄庆; 王景伟; 王鹏程; 邓毅

    2014-01-01

    Toner cartridge as the key component is widely used in laser printer, photocopier and fax machine. As the quantity of discard toner cartridge is increasing year by year, recycling of waste toner cartridge has attracted domestic and international attention. The material composition of waste toner cartridge is introduced, as well as the available recycling of waste toner cartridge and the environ-mental hazard caused by the toners which remained in the cartridge. Simultaneously, processes and technologies applied in waste toner cartridge recycling by domestic and international are summarized. Accordingly, the potential problems existing in waste toner cartridge recycling technologies are discussed, and constructive suggestions for improvement of recycling technology in the future are provided.%硒鼓作为核心部件被广泛应用于激光打印机、复印机和传真机中。随着硒鼓的报废量逐年增大,废弃硒鼓的无害化处理和资源化利用越来越受到人们的关注。主要介绍了废弃硒鼓的材料组分、可资源化性和残留墨粉的环境危害性,总结了国内外废弃硒鼓资源化技术和特点,并提出了废弃硒鼓资源化技术中存在的问题,为未来废弃硒鼓资源化技术的改进提供建设性意见。

  9. Cartridge syringe vs computer controlled local anesthetic delivery system: Pain related behaviour over two sequential visits - a randomized controlled trial.

    Science.gov (United States)

    Thoppe-Dhamodhara, Yogesh-Kumar; Asokan, Sharath; John, Baby-John; Pollachi-Ramakrishnan, GeethaPriya; Ramachandran, Punithavathy; Vilvanathan, Praburajan

    2015-10-01

    Local anesthetic injection is one of the most anxiety provoking procedure in dentistry. Knowledge about change in pain related behaviour during consecutive visits helps in and scheduling of treatment procedures and management of children in dental clinic. To compare the pain perception, behavioural response and the associated change in physiological parameters while receiving local anesthesia injection with cartridge syringe and computer controlled local anesthetic delivery system (CCLAD) over two consecutive visits. In this randomized controlled cross over trial, 120 children aged 7 - 11 years were randomly divided into group A: receiving injections with CCLAD during first visit; group B: receiving injections with cartridge syringe during first visit. The physiological parameters (heart rate and blood pressure) were recorded before and during injection procedure. Objective evaluation of disruptive behaviour and subjective evaluation of pain perceived were done using Face Legs Activity Cry Consolability (FLACC) scale and modified facial image scale (FIS) respectively. No statistical difference in pain response (p= 0.164) and disruptive behaviour (p = 0.120) between cartridge syringe and CCLAD injections were seen during the first visit although the latter showed lesser scores. However, during the second visit there were significant increase in pain response (p = 0.004) and disruptive behaviour (p = 0.006) in cartridge syringe group with an associated increase in heart rate. Injections with CCLAD produced lesser pain ratings and disruptive behaviour than cartridge syringe in children irrespective of order of visit. Behaviour, cartridge syringe, CCLAD, local anesthesia.

  10. DYNAMIC CHARACTERISTICS OF LARGE FLOW RATING ELECTRO-HYDRAULIC PROPORTIONAL CARTRIDGE VALVE

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    A kind of cartridge servo proportional valve is discussed, which can be used for controlling large flow rate with high performance. By analyzing the structure principle of the valve, the transfer function of the valve is derived. With the transfer function, some structure elements that may affect its performance are investigated. Through the numerical simulation and test study, some principles of optimality and effective methods for improving the dynamic performance of the valve are proposed. The test results conform to the results of the theoretical analysis and simulation, which proves the correctness of the study and simulation works. The paper provides theoretical basis for engineering applications and series expanding design works.

  11. The effectiveness of a novel cartridge-based bioreactor design in supporting liver cells.

    Science.gov (United States)

    Niu, Mei; Hammond, Paul; Coger, Robin N

    2009-10-01

    There are a number of applications--ranging from temporary strategies for organ failure to pharmaceutical testing--that rely on effective bioreactor designs. The significance of these devices is that they provide an environment for maintaining cells in a way that allows them to perform key cellular and tissue functions. In the current study, a novel cartridge-based bioreactor was developed and evaluated. Its unique features include its capacity for cell support and the adaptable design of its cellular space. Specifically, it is able to accommodate functional and reasonably sized tissue (>2.0 x 10(8) cells), and can be easily modified to support a range of anchorage-dependent cells. To evaluate its efficacy, it was applied to liver support in the current study. This involved evaluating the performance of rat primary hepatocytes within the unique cartridges in culture--sans bioreactor--and after being loaded within the novel bioreactor. Compared to collagen sandwich culture functional controls, hepatocytes within the unique cartridge design demonstrated significantly higher albumin production and urea secretion rates when cultured under dynamic flow conditions--reaching peak values of 170 +/- 22 microg/10(6) cells/day and 195 +/- 18 microg/10(6) cells/day, respectively. The bioreactor's effectiveness in supporting live and functioning primary hepatocytes is also presented. Cell viability at the end of 15 days of culture in the new bioreactor was 84 +/- 18%, suggesting that the new design is effective in maintaining primary hepatocytes for at least 2 weeks in culture. Liver-specific functions of urea secretion, albumin synthesis, and cytochrome P450 activity were also assessed. The results indicate that hepatocytes are able to achieve good functional performance when cultured within the novel bioreactor. This is especially true in the case of cytochrome P450 activity, where by day 15 of culture, hepatocytes within the bioreactor reached values that were 56.6% higher

  12. Novel pre-fractionation method of trans fatty acids by gas chromatography with silver-ion cartridge column.

    Science.gov (United States)

    Goto, Hirofumi; Shionoya, Noriko; Sugie, Megumi; Tominaga, Makoto; Shimelis, Olga; Taniguchi, Makoto; Igarashi, Tomoji; Hirata, Yoshiaki

    2012-01-01

    We developed a novel pre-separation method of trans fatty acids (TFAs) using a silver-ion cartridge column and GC. As a preliminary study, a mixture of fatty acid methyl esters consisting of saturated, cis-unsaturated, and trans-unsaturated fatty acids was dissolved in dichloromethane and loaded onto a Bond Elut SCX ion-exchange cartridge column that was converted to the silver-ion form. The column was then eluted with dichloromethane to obtain the saturated fatty acids, dichloromethane/ethyl acetate (90/10) for the trans mono-ene, dichloromethane/ethyl acetate (65/35) for the cis mono-ene, dichloromethane/acetone (60/40) for the trans di-ene, and acetone/acetonitrile (80/20) for the others. Satisfactory separation of the cis/trans isomers was confirmed by GC analysis. To generalize this technique, the elution conditions of the ready-to-use Discovery Ag-ION SPE cartridge column were also optimized. Both cartridge columns had good separation, recovery, and repeatability. Peer laboratory verification was carried out between two laboratories using different production lots of the ready-to-use cartridge column, and the robustness of the product and reproducibility of the method were found to be satisfactory. This technique is therefore a powerful tool not only for routine analyses of TFAs in oils, fats, and foods but also for detailed analyses of TFAs in various research fields.

  13. Model Free Approach for Non-Isothermal Decomposition of Un-Irradiated and g-Irradiated Silver Acetate: New Route for Synthesis of Ag2O Nanoparticles

    Directory of Open Access Journals (Sweden)

    Naser M. Abd El-Salam

    2010-09-01

    Full Text Available Kinetic studies for the non-isothermal decomposition of unirradiated and γ‑irradiated silver acetate with 103 kGy total γ-ray doses were carried out in air. The results showed that the decomposition proceeds in one major step in the temperature range of (180–270 °C with the formation of Ag2O as solid residue. The non-isothermal data for un‑irradiated and γ-irradiated silver acetate were analyzed using Flynn-Wall-Ozawa (FWO and nonlinear Vyazovkin (VYZ iso-conversional methods. These free models on the investigated data showed a systematic dependence of Ea on a indicating a simple decomposition process. No significant changes in the thermal decomposition behavior of silver acetate were recorded as a result of γ-irradiation. Calcinations of γ-irradiated silver acetate (CH3COOAg at 200 °C for 2 hours only led to the formation of pure Ag2O mono-dispersed nanoparticles. X-ray diffraction, FTIR and SEM techniques were employed for characterization of the synthesized nanoparticles.

  14. 弹射药筒局部热处理%Local Thermal Treatment on Catapult Cartridge

    Institute of Scientific and Technical Information of China (English)

    闻国民; 杨国义; 牛俊杰; 魏军伟; 陈全明

    2014-01-01

    针对弹射药筒局部热处理的质量性能要求,对感应加热技术进行研究。基于加热时间、温度和升温速度对筒壁的影响,从频率选择、感应器和工装设计3个方面进行分析,得到频率、功率和时间参数。分析结果表明:该方法使工件的抗拉强度、延伸率达到了要求,产品性能稳定,并能有效控制药筒口部的物理性能。%The technology of induction heating fusing had been researched in allusion to the demand of quality and property of the local thermal treatment on catapult cartridge. In view of the effect on cylinder wall about heating time, temperature and the rate of warming, parameter of frequency, temperature and time had been found according to the analysis in these three points including frequency selection, sensors and equipment design. Interrelated analyses concluded that these measures ensured the tensile strength and elongation, and made the performance stable. Also, physical properties of cartridge mouth had been controlled effectively.

  15. Hydrogen Car Cartridges: A New Strategy for Hydrogen Storage, Delivering and Refueling

    Energy Technology Data Exchange (ETDEWEB)

    Prosini, Pier Paolo

    2007-07-01

    The purpose of the project is to introduce a sustainable model in the automotive field, guarantying the Kyoto agreements. The aim of the project is to develop an innovative hydrogen tank able to power an hydrogen fuel cell car with the same performance of liquid fuelled cars. Most of the system performance are expected to satisfy the Department of Energy (DOE) goals for 2015. The hydrogen releasing system is based on solid NaBH4 which is hydrolyzed with water or steam to obtain hydrogen. Sodium borate is obtained as by-product and it has to be recycled. Pure and humidified hydrogen, ready to be utilized in a fuel cell, is obtained by a simple and sure way. Hydrogen is produced only when it is requested and therefore there is never pressurized hydrogen or hydrogen overproduction The system works at atmospheric pressure avoiding the problems related to handling and storing pressurized gas. The car fuelling could be performed in area like the present service stations. The used cartridges can be removed and substituted by new cartridges. Contemporarily a water tank should be refilled. To improve the total energetic yield it was also proposed a NaBH4 regeneration process directly starting from the products of hydrolysis. (auth)

  16. Comparison of systems for high speed surface flaw measurements of cartridges

    Energy Technology Data Exchange (ETDEWEB)

    Swinth, K. L.; Kirihara, L. J.; Coleman, W. J.

    1979-01-01

    Instrumentation to detect surface flaws in cartridge cases has been developed for high speed on-line inspection. Scattering of light from a line focused on the case surface indicates the presence of surface flaws and the instrumentation permits rough categorization of flaws into dents and scratches. Two methods of light detection have been implemented, and the purpose of this paper is to compare these techniques. The first technique uses fiber optics to collect the scattered light and carry it to a photomultiplier tube to generate a signal, which the second technique uses solid-state diodes to produce the signal. Angled surfaces such as the shoulder on the cartridge case influence the response of the fiber-optics due to the acceptance cone of the fibers. To circumvent this problem, the fibers must be judiciously positioned during manufacture of the fiber-optic bundles. The solid-state diodes do not have the limited acceptance angle and thus provide more uniform response. However, the diodes require placement of electronics on the rotating exam wheel near the detectors. The processing electronics for both systems are identical.

  17. A Calibration-Free, Noncontact, Disposable Liquid Dispensing Cartridge Featuring an Online Process Control.

    Science.gov (United States)

    Bammesberger, Stefan Borja; Malki, Imad; Ernst, Andreas; Zengerle, Roland; Koltay, Peter

    2014-08-01

    We present a noncontact liquid dispenser that uses a disposable cartridge for the calibration-free dosage of diverse biochemical reagents from the nanoliter to the microliter range. The dispensing system combines the advantages of a positive displacement syringe pump (responsible for defining the aliquot's volume with high accuracy) with a highly dynamic noncontact dispenser (providing kinetic energy to detach the liquid from the tip). The disposable, noncontact dispensing cartridge system renders elaborate washing procedures of tips obsolete. A noncontact sensor monitors the dispensing process to enable an online process control. To further increase confidence and reliability for particularly critical biomedical applications, an optional closed-loop control prevents malfunctions. The dispensing performance was characterized experimentally in the range of 0.25 to 10.0 µL using liquids of different rheological properties (viscosity 1.03-16.98 mPas, surface tension 30.49-70.83 mN/m) without adjusting or calibrating the actuation parameters. The precision ranged between a coefficient of variation of 0.5% and 5.3%, and the accuracy was below ±10%. The presented technology has the potential to contribute significantly to the improvement of biochemical liquid handling for laboratory automation in terms of usability, miniaturization, cost reduction, and safety.

  18. Ophthalmic viscosurgical device backflow into cartridge during intraocular lens insertion using injectors

    Directory of Open Access Journals (Sweden)

    Matsuura K

    2014-01-01

    Full Text Available Kazuki Matsuura,1 Yoshitsugu Inoue2 1Nojima Hospital, 2Tottori University, Kurayoshi City, Tottori, Japan Background: The purpose of this study was to assess the risk of intraocular contamination caused by intraocular lens (IOL insertion with injectors by observing the dynamics of an ophthalmic viscosurgical device (OVD. Methods: Each type of injector was equipped with a colored OVD and IOL, and a 2 mm length from the tip of the cartridge was replaced with a colored OVD. The various combinations of IOLs and injectors used were: a three-piece shaped IOL, VA60BBR + TypeE1 (HOYA incision size 2.5 mm; group A, n=5; a single-piece IOL, 251+ iSert micro, preloaded (HOYA, incision size 2.2 mm; group G, n=5; and a single-piece IOL, SN6CWS preloaded (Alcon, incision size 2.7 mm; group C, n=5. Results: In group A, the intraocular OVD instantly flowed backward into the injector, whereas the colored OVD was pushed backward deep inside the cartridge without flowing into the eye. In group B, the backflow of the intraocular OVD into the injector was limited, resulting in the influx of a large amount of the colored OVD into the eye along with the IOL. In group C, as in group A, a large amount of the intraocular OVD flowed backward into the injector. Consequently, a small amount of the colored OVD flowed into the eye. Conclusion: The tip of the injector and OVD could be contaminated because the surgical field cannot be completely sterile, even after preoperative disinfection. Our experiments revealed that OVD backflow into the injector cavity occurs during IOL insertion, and this phenomenon may have minimized intraocular contamination. However, small-diameter cartridges along with plate-type haptics allow insufficient OVD backflow, resulting in intraocular influx of the contaminated OVD. Surgeons have to be notified that intraoperative bacterial contamination can occur even after IOL insertion using injectors. Keywords: intraocular lens insertion

  19. Detection and genotyping of human papillomavirus in self-obtained cervicovaginal samples by using the FTA cartridge: new possibilities for cervical cancer screening.

    NARCIS (Netherlands)

    Lenselink, C.H.; Bie, R.P. de; Hamont, D. van; Bakkers, J.M.J.E.; Quint, W.G.V.; Massuger, L.F.A.G.; Bekkers, R.L.M.; Melchers, W.J.G.

    2009-01-01

    This study assesses human papillomavirus (HPV) detection and genotyping in self-sampled genital smears applied to an indicating FTA elute cartridge (FTA cartridge). The study group consisted of 96 women, divided into two sample sets. All samples were analyzed by the HPV SPF(10)-Line Blot 25. Set 1

  20. Antifingerprint property of the hard coat for cartridge-free Blu-ray Disc

    Science.gov (United States)

    Hayashida, Naoki; Itoh, Hidetake; Yoneyama, Kenji; Kato, Tatsuya; Tanaka, Kazushi; Utsunomiya, Hajime

    2003-09-01

    We made improvements on the previously reported hard-coat for cartridge-free Blu-ray disc from a viewpoint of an anti-fingerprint property. As a result of this study, two types of the hard-coat have been obtained. One is for Blu-ray discs of ROM and write-once types, and the other is for that of rewritable type. The former well inhibited a deterioration of bit error rate (bER) of the signal written prior to the fingerprint adhesion. The later exhibited low bER for the data signals written both before and after the fingerprint adhesion. These results are attributable to the area ratio of drops of fingerprint-ingredient on the disc surface, and the low area ratio resulted in a low bER. Moreover, it was confirmed that the disc with higher contact angle of oily compound exhibited the lower area ratio of the fingerprint.

  1. Radiological assessment of cartridge 120-mm, APFSDS-T, XM829 ammunition

    Energy Technology Data Exchange (ETDEWEB)

    Hooker, C.D.; Hadlock, D.E.; Soldat, K.L.; Gilchrist, R.L.

    1983-12-01

    The components of the XM829 round effectively shield out nonpenetrating beta radiation emitted by the depleted uranium; however, photons cna penetrate the components of the round and are therefore the predominant emission. The radiation levels associated with the XM829 ammunition are low. The maximum emissions measured from a cartridge are not likely to result in exposure to military personnel above the maximum permissible nonoccupational dose limits listed in Army Regulation (AR) 40-14. Based upon the specifications contained in 49 CFR 173.424 and the radiation measurement data, the XM829 shipping package may be excepted from the specification packaging, marking and labeling requirements of subpart 49 CFR 173 as long as the outer surface of the uranium is enclosed in an inactive sheath and the conditions specified in 49 CFR 421 (b), (c), and (d) are met.

  2. Thermal spray forming of refractory sample ampoule cartridges for single crystal growth space furnaces

    Science.gov (United States)

    Zimmerman, Frank; Poorman, Richard; Holmes, Richard; Mckechnie, Timothy; Krotz, Phil; Liaw, Yoon

    1993-01-01

    A thermal spray process is being used to build up refractory metals and ceramics into a containment cartridge for high temperature, single crystal semiconductor growth experiments. This process uses high energy plasma inside a low pressure (100-200 torr) inert environment to apply layers of material onto a removable mandrel. A variety of materials are being characterized and evaluated against a demanding set of requirements, including high service temperature (1700 C), oxidation resistance, and resistance to liquid metal attack. Techniques to spray form refractory metals (tungsten, molybdenum, niobium, tantalum) and ceramics (alumina, boron nitride) are being developed in the Plasma Spray Cell at Marshall Space Flight Center. These plasma spray formed materials have been evaluated for mechanical properties, density, microstructure, and resistance to liquid metal attack. Forming techniques and the resultant mechanical and metallurgical properties are presented.

  3. Extraction and PerconcentrationLead (II Using Octadecyl Bonded Silica Cartridge and Determination by FAAS

    Directory of Open Access Journals (Sweden)

    Moghimi A. Shaabanzadeh M.

    2012-01-01

    Full Text Available A simple method has been developed for the preconcentration of Lead (II based on the adsorption of its 1-(2-Pyridyl Azo2-Naphtol (PAN complex on aOctadecyl bonded silica cartridges. The influence of acidity, eluting agents, stability of the column, sample volume and interfering ions has been investigated in detail. The adsorbed complex could be eluted using environmentally benign HNO34M and the concentration of Lead (II was determined flame atomic absorption spectrometry. A detection limit of 50 µgL−1 could be achieved and the developed procedure was successfully applied for the determination of Lead (II in tap water and waste water samples. 

  4. A Modified Electrostatic Adsorption Apparatus for Latent Fingerprint Development on Unfired Cartridge Cases.

    Science.gov (United States)

    Xu, Jingyang; Zhang, Ziyuan; Zheng, Xiaochun; Bond, John W

    2016-12-13

    Visualization of latent fingerprints on metallic surfaces by the method of applying electrostatic charging and adsorption is considered as a promising chemical-free method, which has the merit of nondestruction, and is considered to be effective for some difficult situations such as aged fingerprint deposits or those exposed to environmental extremes. In fact, a portable electrostatic generator can be easily accessible in a local forensic technology laboratory, which is already widely used in the visualization of footwear impressions. In this study, a modified version of this electrostatic apparatus is proposed for latent fingerprint development and has shown great potential in visualizing fingerprints on metallic surfaces such as cartridge cases. Results indicate that this experimental arrangement can successfully develop aged latent fingerprints on metal surfaces, and we demonstrate its effectiveness compared with existing conventional fingerprint recovery methods.

  5. Characterization of filter cartridges from the IEA-R1 reactor by radiochemical method

    Energy Technology Data Exchange (ETDEWEB)

    Geraldo, Bianca; Vicente, Roberto; Ferreira, Robson J.; Goes, Marcos M.; Marumo, Julio T., E-mail: bgeraldo@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2015-07-01

    The filter cartridges used in water purification system of research nuclear reactor IEA-R1 are considered radioactive wastes after their useful life. The characterization of these wastes is one of the stages of management, which aims to identify and quantify the radionuclides present, including those known as 'difficult to measure' (DTM) radionuclides. Establish a radiochemical analysis methodology for this type of waste is a difficult job, not only by the application of these techniques, but also by the amount of radionuclides that should be analyzed. In the waste produced in a nuclear reactor, the most important radionuclides are fission products, activation products and transuranic elements. Since these radionuclides emit gamma radiation not measurable in its decay process and consequently are difficult to measure, their concentrations can be estimated by indirect methods such as scale factors. This method is used to evaluate the DTM concentration, which is represented by alpha and beta nuclides using the correlation between them and the radionuclide key, a gamma emitter. The objective of this work is to describe a radiochemical analysis methodology for gamma emitter nuclides, present in the filter cartridges, evaluating the activity and concentrations by destructive assays. At the same time, two studies have been performed by non-destructive assays, the first one based on dose rates and the point kernel method to correlate the results and the second one based on calibration efficiency with Monte Carlo method. These studies belong to the radioactive waste characterization program that has been conducted at the Waste Management Laboratory of Nuclear and Energy Research Institute, IPEN-CNEN/SP. (author)

  6. Differentiation of coloured inks of inkjet printer cartridges by thin layer chromatography and high performance liquid chromatography.

    Science.gov (United States)

    Poon, N L; Ho, S S H; Li, C K

    2005-01-01

    Document examiners are frequently asked to determine whether or not a colour printout has originated from a particular inkjet printer. The printer can rarely be identified unless some unique defects or irregularities of the printer are present on the printout. However, it is possible to decipher the make and/or model of the printer by comparing the ink-profile of the questioned printout with that of a seized inkjet printer cartridge or from one in a database. This paper presents an overview of a systematic approach to characterising and discriminating the inks of different inkjet printer cartridges using thin layer chromatography (TLC) and high pressure liquid chromatography (HPLC) with multi-wavelength ultra-violet/visible (UV/Vis) detection. Ink samples from 23 different inkjet printer cartridges (including originals and substitutes) of different brands and colour printouts, printed by known printers were examined with newly developed chromatographic methods. Subsequently, a database of the ink-profiles was generated. The methods provide a useful tool for discriminating coloured inks in inkjet printer cartridges of different brands.

  7. On Prevention of Steam Boiler Heating Surface Cartridge Igniter%浅谈蒸汽锅炉受热面爆管的预防

    Institute of Scientific and Technical Information of China (English)

    李宇翔

    2013-01-01

    This article analyzes the causes of steam boiler heating surface cartridge igniter and presents the main points of preventing steam boiler heating surface abrading cartridge igniter and tips for reducing back-end heating surface abrading cartridge igniter.%本文分析了蒸汽锅炉受热面爆管的原因,指出了防止锅炉受热面磨损爆管应注意的要点以及减少尾部受热面磨损爆管应注意的问题。

  8. EXPERIMENT OF THE PERFORMANCE OF HOME-MADE ACTIVATED CARBON FIBRE CARTRIDGE%国产活性炭纤维滤芯性能测试

    Institute of Scientific and Technical Information of China (English)

    万春新; 陈建国; 黄金钟; 胡望钧

    2001-01-01

    本文通过对国产活性炭纤维滤芯与国外进口活性炭纤维滤芯进行的各项性能对比测试结果的分析,指出国产活性炭纤维滤芯可替代国外进口同类产品。%The performance of home-made and import activated carbon fibre cartridge is studied here. By comparing the performances of these two kinds, we found that home-made activated carbon fibre cartridge can be substituted for import activated carbon fibre cartridge of the same kind.

  9. Investigating Premature Ignition of Thruster Pressure Cartridges by Mechanical Impact of Internal Components

    Science.gov (United States)

    Woods, Stephen S.; Saulsberry, Regor

    2010-01-01

    Pyrotechnic thruster pressure cartridges (TPCs) are used for aeroshell separation on a new NASA crew launch vehicle. The premature ignition concern was hypothesized based on the potential range of motion of the subassemblies, projected worst case accelerations, and the internal geometry that could subject propellant grains to mechanical impact sufficiently high for ignition. This possibility was investigated by fabricating a high-fidelity model of the suspected contact geometry, placing a representative amount of propellant in it, and impacting the propellant with a range of forces equivalent to and greater than the maximum possible during launch. Testing demonstrated that the likelihood of ignition is less than 1 in 1,000,000. The test apparatus, methodology, and results are described in this paper. Nondestructive evaluation ( NDE) during TPC acceptance testing indicated that internal assemblies moved during shock and vibration testing due to an internal bond anomaly. This caused concerns that the launch environment might produce the same movement and release propellant grains that might be prematurely ignited through impact or through electrostatic discharge (ESD) as grains vibrated against internal surfaces. Since a new lot could not be fabricated in time, a determination had to be made as to whether the lot was acceptable to fly. This paper discusses the analysis and impact testing used to address the potential impact issue and a separate paper addresses the ESD issue.

  10. A new model of repulsive force in eddy current separation for recovering waste toner cartridges.

    Science.gov (United States)

    Ruan, Jujun; Xu, Zhenming

    2011-08-15

    Eddy current separation (ECS) is an efficient method for separating aluminum from plastic in crushed waste toner cartridge (TCs). However, in China, ECS quality of aluminum from plastic is rather low in production practice. Repeating separation even manual sorting is required in the production. Improving separation quality of aluminum has been the pressing problem in the recovery of waste TCs. Furthermore, improving ECS quality can reduce the secondary-pollution (furan and dioxin) brought by plastic in later smelting process for the purification of recovered aluminum. Thus, a new model of repulsive force containing impact factors (machine: B(r), k, R, S(m), B(m); material: S(p), V, γ; and operation: ω(m), v, δ) of the separation process was constructed for guiding the ECS process of waste TCs recovering in this paper. For testing whether the model of repulsive force was suitable to guide the ECS, calculation and experiment of detachment angle of aluminum flake were studied. The calculation results of the detachment angles were agreed with the testing experiment. It indicates that the model is suitable for guiding the ECS of waste TCs recovering. Copyright © 2011 Elsevier B.V. All rights reserved.

  11. Efficient substructure searching of large chemical libraries: the ABCD chemical cartridge.

    Science.gov (United States)

    Agrafiotis, Dimitris K; Lobanov, Victor S; Shemanarev, Maxim; Rassokhin, Dmitrii N; Izrailev, Sergei; Jaeger, Edward P; Alex, Simson; Farnum, Michael

    2011-12-27

    Efficient substructure searching is a key requirement for any chemical information management system. In this paper, we describe the substructure search capabilities of ABCD, an integrated drug discovery informatics platform developed at Johnson & Johnson Pharmaceutical Research & Development, L.L.C. The solution consists of several algorithmic components: 1) a pattern mapping algorithm for solving the subgraph isomorphism problem, 2) an indexing scheme that enables very fast substructure searches on large structure files, 3) the incorporation of that indexing scheme into an Oracle cartridge to enable querying large relational databases through SQL, and 4) a cost estimation scheme that allows the Oracle cost-based optimizer to generate a good execution plan when a substructure search is combined with additional constraints in a single SQL query. The algorithm was tested on a public database comprising nearly 1 million molecules using 4,629 substructure queries, the vast majority of which were submitted by discovery scientists over the last 2.5 years of user acceptance testing of ABCD. 80.7% of these queries were completed in less than a second and 96.8% in less than ten seconds on a single CPU, while on eight processing cores these numbers increased to 93.2% and 99.7%, respectively. The slower queries involved extremely generic patterns that returned the entire database as screening hits and required extensive atom-by-atom verification.

  12. Disposable pen-shaped capillary gel electrophoresis cartridge for fluorescence detection of bio-molecules

    Science.gov (United States)

    Amirkhanian, Varoujan; Tsai, Shou-Kuan

    2014-03-01

    We introduce a novel and cost-effective capillary gel electrophoresis (CGE) system utilizing disposable pen-shaped gelcartridges for highly efficient, high speed, high throughput fluorescence detection of bio-molecules. The CGE system has been integrated with dual excitation and emission optical-fibers with micro-ball end design for fluorescence detection of bio-molecules separated and detected in a disposable pen-shaped capillary gel electrophoresis cartridge. The high-performance capillary gel electrophoresis (CGE) analyzer has been optimized for glycoprotein analysis type applications. Using commercially available labeling agent such as ANTS (8-aminonapthalene-1,3,6- trisulfonate) as an indicator, the capillary gel electrophoresis-based glycan analyzer provides high detection sensitivity and high resolving power in 2-5 minutes of separations. The system can hold total of 96 samples, which can be automatically analyzed within 4-5 hours. This affordable fiber optic based fluorescence detection system provides fast run times (4 minutes vs. 20 minutes with other CE systems), provides improved peak resolution, good linear dynamic range and reproducible migration times, that can be used in laboratories for high speed glycan (N-glycan) profiling applications. The CGE-based glycan analyzer will significantly increase the pace at which glycoprotein research is performed in the labs, saving hours of preparation time and assuring accurate, consistent and economical results.

  13. Microfluidic impact printer with interchangeable cartridges for versatile non-contact multiplexed micropatterning.

    Science.gov (United States)

    Ding, Yuzhe; Huang, Eric; Lam, Kit S; Pan, Tingrui

    2013-05-21

    Biopatterning has been increasingly used for well-defined cellular microenvironment, patterned surface topology, and guided biological cues; however, it meets challenges on biocompatibility, thermal and chemical sensitivity, as well as limited availability of reagents. In this paper, we aim at combining the desired features from non-contact inkjet printing and dot-matrix impact printing to establish a versatile multiplexed micropatterning platform, referred to as Microfluidic Impact Printer (MI-Printer), for emerging biomedical applications. Using this platform, we can achieve the distinct features of no cross-contamination, sub-microliter ink loading with a minimal dead volume, high-throughput printing, biocompatible non-contact processing, sequential patterning with self-alignment, wide adaptability for complex media (e.g., cell suspension or colloidal solutions), interchangeable/disposable cartridge design, and simple assembly and configuration, all highly desirable towards laboratory-based research and development. Specifically, the printing resolution of the MI-printer platform has been experimentally characterized and theoretically analysed. Optimal printing resolution of 80 μm has been repeatedly obtained. Furthermore, two useful functions of the MI-printer, multiplexed printing and combinatorial printing, have been experimentally demonstrated with less than 10 μm misalignment. Moreover, molecular and biological patterning, utilizing the multiplexed and combinatorial printing, has been implemented to illustrate the utility of this versatile printing technique for emerging biomedical applications.

  14. Maintaining accuracy of cellular Yule-Nielsen spectral Neugebauer models for different ink cartridges using principal component analysis.

    Science.gov (United States)

    Wang, Binyu; Xu, Haisong; Luo, M Ronnier; Guo, Jinyi

    2011-07-01

    The replacement of used-up ink cartridges is unavoidable, but it makes the existing characterization model far from accurate, while recharacterization is labor intensive. In this study, we propose a new correction method for cellular Yule-Nielsen spectral Neugebauer (CYNSN) models based on principal component analysis (PCA). First, a small set of correction samples are predicted, printed using new ink cartridges, and then measured. Second, the link between the predicted and measured reflectance weights, generated by PCA, is determined. The experimental results show that the proposed method provides a significant and robust improvement, since not only the color change between original and new inks but also the systemic error of CYNSN modelsis taken into account in the method.

  15. Characterization of Plasma Gun with TiH2/C60 Cartridge for Disruption Mitigation in Tokamaks

    Science.gov (United States)

    Bogatu, I. N.; Thompson, J. R.; Galkin, S. A.; Kim, J. S.; HyperV Technologies Corp. Team

    2011-10-01

    Impurity injection for disruption mitigation in tokamaks must be faster than growth time of plasma instabilities, requires sufficient mass to get critical electron density, high penetrability, and large assimilation fraction in the core plasma, with rapid impurity redistribution over the whole plasma. FAR-TECH, Inc. proposed the innovative idea to use hyper-velocity (>30 km/s), high-density (>1023 m-3) C60/C plasma jets with high ram pressure to deliver the impurity mass in plasma accelerator. We report the complete characterization of the TiH2/C60 cartridge with 5 kJ capacitive driver which demonstrated the capability of producing >30 mg of C60 gas in coaxial plasma gun (~35 cm length) prototype with TiH2/C60 cartridge for a small scale, proof-of-principle experiment on a tokamak. Work supported by the US DOE DE-FG02-08ER85196 grant.

  16. Development and Preliminary Assessment of Hemoperfusion Cartridge with Tannic Acid for Toxic Proteins' Precipitation: An In Vitro Model

    Directory of Open Access Journals (Sweden)

    Valquíria Miwa Hanai Yoshida

    2016-09-01

    Full Text Available Charcoal hemoperfusion (CHP is one of the extracorporeal removal techniques that are used to remove toxins from the body. CHP generally is considered the preferred method for extracorporeal extraction of several toxins—toxins that are adsorbed by activated charcoal. Assessments of the tannic acid's protective effects on ophidian poisoning are associated with the toxic proteins' precipitation by tannic acid. The challenge in treating a snakebite lies in removing the injected poison with minimal damage to blood constituent proteins. An alternative is CHP, and this investigation proposed to develop a column for hemoperfuser cartridge, combining charcoal granules trapped between layers of polymeric material conjugated to tannic acid, using an in vitro model scaled to the Wistar rat, which can be tested in an animal model. The cartridge was evaluated using the 22 full factorial design, in duplicate, as a method to study the effects of granulated-charcoal size and tannic acid concentration on the hematologic profile (platelet and leukocyte counts and biochemical profile (total serum protein and albumin dosages of sheep blood. The results demonstrate that charcoal in hemoperfuser cartridge: (1 decreases the serum in sheep blood volume, as consequence, (2 increases the serum proteins' concentration, and (iii exerts slight influence on albumin. The inclusion of tannic acid in hemoperfuser column precipitates some of serum proteins and albumin, decreasing their concentrations in the plasma serum. In conclusion, based on these effects we can suggest the use of 0.02 g tannic acid concentration and 8–20 mesh granulated charcoal in hemoperfuser cartridge for precipitating toxic proteins from snake venoms.

  17. Polyvinyl Acetate Resin as a Binder Effecting Mechanical and CombustionProperties of Combustible Cartridge Case Formulations

    OpenAIRE

    M.T. Shedge; C.H. Patel; S.K. Tadkod; G.D. Murthy

    2008-01-01

    Several combustible cartridge case (CCC) formulations containing nitrocellulose (NC) as anenergetic ingredient with diphenylamine (DPA) as stabiliser, cellulose fiber as reinforcing materialand polyvinyl acetate (PVAc) as a binder are processed to form combustible discs. A formulationcontaining  nitrocellulose (83 parts), cellulose (17 parts) , PVAc (20 parts) and  diphenylamine(1 part) by weight was observed with the improvement of  mechanical properties without anyadverse effect on combusti...

  18. Integration of an Optical Ring Resonator Biosensor into a Self-Contained Microfluidic Cartridge with Active, Single-Shot Micropumps

    Directory of Open Access Journals (Sweden)

    Sascha Geidel

    2016-09-01

    Full Text Available While there have been huge advances in the field of biosensors during the last decade, their integration into a microfluidic environment avoiding external tubing and pumping is still neglected. Herein, we show a new microfluidic design that integrates multiple reservoirs for reagent storage and single-use electrochemical pumps for time-controlled delivery of the liquids. The cartridge has been tested and validated with a silicon nitride-based photonic biosensor incorporating multiple optical ring resonators as sensing elements and an immunoassay as a potential target application. Based on experimental results obtained with a demonstration model, subcomponents were designed and existing protocols were adapted. The newly-designed microfluidic cartridges and photonic sensors were separately characterized on a technical basis and performed well. Afterwards, the sensor was functionalized for a protein detection. The microfluidic cartridge was loaded with the necessary assay reagents. The integrated pumps were programmed to drive the single process steps of an immunoassay. The prototype worked selectively, but only with a low sensitivity. Further work must be carried out to optimize biofunctionalization of the optical ring resonators and to have a more suitable flow velocity progression to enhance the system’s reproducibility.

  19. Regulation of Chandelier Cell Cartridge and Bouton Development via DOCK7-Mediated ErbB4 Activation

    Directory of Open Access Journals (Sweden)

    Yilin Tai

    2014-01-01

    Full Text Available Chandelier cells (ChCs, typified by their unique axonal morphology, are the most distinct interneurons present in cortical circuits. Via their distinctive axonal terminals, called cartridges, these cells selectively target the axon initial segment of pyramidal cells and control action potential initiation; however, the mechanisms that govern the characteristic ChC axonal structure have remained elusive. Here, by employing an in utero electroporation-based method that enables genetic labeling and manipulation of ChCs in vivo, we identify DOCK7, a member of the DOCK180 family, as a molecule essential for ChC cartridge and bouton development. Furthermore, we present evidence that DOCK7 functions as a cytoplasmic activator of the schizophrenia-associated ErbB4 receptor tyrosine kinase and that DOCK7 modulates ErbB4 activity to control ChC cartridge and bouton development. Thus, our findings define DOCK7 and ErbB4 as key components of a pathway that controls the morphological differentiation of ChCs, with implications for the pathogenesis of schizophrenia.

  20. Investigating Premature Ignition of Thruster Pressure Cartridges by Vibration-Induced Electrostatic Discharge

    Science.gov (United States)

    Woods, Stephen S.; Saulsberry, Regor

    2010-01-01

    Pyrotechnic thruster pressure cartridges (TPCs) are used for aeroshell separation on a new NASA crew launch vehicle. Nondestructive evaluation (NDE) during TPC acceptance testing indicated that internal assemblies moved during shock and vibration testing due to an internal bond anomaly. This caused concerns that the launch environment might produce the same movement and release propellant grains that might be prematurely ignited through impact or through electrostatic discharge (ESD) as grains vibrated against internal surfaces. Since a new lot could not be fabricated in time, a determination had to be made as to whether the lot was acceptable to fly. This paper discusses the ESD evaluation and a separate paper addresses the impact problem. A challenge to straight forward assessment existed due to the unavailability of triboelectric data characterizing the static charging characteristics of the propellants within the TPC. The approach examined the physical limitations for charge buildup within the TPC system geometry and evaluated it for discharge under simulated vibrations used to qualify components for launch. A facsimile TPC was fabricated using SS 301 for the case and surrogate worst case materials for the propellants based on triboelectric data. System discharge behavior was evaluated by applying high voltage to the point of discharge in air and by placing worst case charge accumulations within the facsimile TPC and forcing discharge. The facsimile TPC contained simulated propellant grains and lycopodium, a well characterized indicator for static discharge in dust explosions, and was subjected to accelerations equivalent to the maximum accelerations possible during launch. The magnitude of charge generated within the facsimile TPC system was demonstrated to lie in a range of 100 to 10,000 times smaller than the spark energies measured to ignite propellant grains in industry standard discharge tests. The test apparatus, methodology, and results are described in

  1. Screening of peptide libraries against protective antigen of Bacillus anthracis in a disposable microfluidic cartridge.

    Directory of Open Access Journals (Sweden)

    Joshua M Kogot

    Full Text Available Bacterial surface peptide display has gained popularity as a method of affinity reagent generation for a wide variety of applications ranging from drug discovery to pathogen detection. In order to isolate the bacterial clones that express peptides with high affinities to the target molecule, multiple rounds of manual magnetic activated cell sorting (MACS followed by multiple rounds of fluorescence activated cell sorting (FACS are conventionally used. Although such manual methods are effective, alternative means of library screening which improve the reproducibility, reduce the cost, reduce cross contamination, and minimize exposure to hazardous target materials are highly desired for practical application. Toward this end, we report the first semi-automated system demonstrating the potential for screening bacterially displayed peptides using disposable microfluidic cartridges. The Micro-Magnetic Separation platform (MMS is capable of screening a bacterial library containing 3 × 10¹⁰ members in 15 minutes and requires minimal operator training. Using this system, we report the isolation of twenty-four distinct peptide ligands that bind to the protective antigen (PA of Bacilus anthracis in three rounds of selection. A consensus motif WXCFTC was found using the MMS and was also found in one of the PA binders isolated by the conventional MACS/FACS approach. We compared MMS and MACS rare cell recovery over cell populations ranging from 0.1% to 0.0000001% and found that both magnetic sorting methods could recover cells down to 0.0000001% initial cell population, with the MMS having overall lower standard deviation of cell recovery. We believe the MMS system offers a compelling approach towards highly efficient, semi-automated screening of molecular libraries that is at least equal to manual magnetic sorting methods and produced, for the first time, 15-mer peptide binders to PA protein that exhibit better affinity and specificity than peptides

  2. {sup 14}CO{sub 2} processing using an improved and robust molecular sieve cartridge

    Energy Technology Data Exchange (ETDEWEB)

    Wotte, Anja, E-mail: Anja.Wotte@uni-koeln.de [Institute of Geology and Mineralogy, University of Cologne, Cologne (Germany); Wordell-Dietrich, Patrick [Thünen Institute of Climate-Smart Agriculture, Braunschweig (Germany); Wacker, Lukas [Ion Beam Physics, ETH Zurich, Zurich (Switzerland); Don, Axel [Thünen Institute of Climate-Smart Agriculture, Braunschweig (Germany); Rethemeyer, Janet [Institute of Geology and Mineralogy, University of Cologne, Cologne (Germany)

    2017-06-01

    Radiocarbon ({sup 14}C) analysis on CO{sub 2} can provide valuable information on the carbon cycle as different carbon pools differ in their {sup 14}C signature. While fresh, biogenic carbon shows atmospheric {sup 14}C concentrations, fossil carbon is {sup 14}C free. As shown in previous studies, CO{sub 2} can be collected for {sup 14}C analysis using molecular sieve cartridges (MSC). These devices have previously been made of plastic and glass, which can easily be damaged during transport. We thus constructed a robust MSC suitable for field application under tough conditions or in remote areas, which is entirely made of stainless steel. The new MSC should also be tight over several months to allow long sampling campaigns and transport times, which was proven by a one year storage test. The reliability of the {sup 14}CO{sub 2} results obtained with the MSC was evaluated by detailed tests of different procedures to clean the molecular sieve (zeolite type 13X) and for the adsorption and desorption of CO{sub 2} from the zeolite using a vacuum rig. We show that the {sup 14}CO{sub 2} results are not affected by any contamination of modern or fossil origin, cross contamination from previous samples, and by carbon isotopic fractionation. In addition, we evaluated the direct CO{sub 2} transfer from the MSC into the automatic graphitization equipment AGE with the subsequent {sup 14}C AMS analysis as graphite. This semi-automatic approach can be fully automated in the future, which would allow a high sample throughput. We obtained very promising, low blank values between 0.0018 and 0.0028 F{sup 14}C (equivalent to 50,800 and 47,200 yrs BP), which are within the analytical background and lower than results obtained in previous studies.

  3. Radiation induced synthesis of In{sub 2}O{sub 3} nanoparticles - Part II: Synthesis of In{sub 2}O{sub 3} nanoparticles by thermal decomposition of un-irradiated and γ-irradiated indium acetylacetonate

    Energy Technology Data Exchange (ETDEWEB)

    Al-Resheedi, Ajayb Saud; Alhokbany, Norah Saad [Department of Chemistry, College of Science, King Saud University, KSU, (Saudi Arabia); Mahfouz, Refaat Mohammed, E-mail: rmhfouz@science.au.edu.eg [Chemistry Department, Faculty of Science, Assiut University, AUN, (Egypt)

    2015-09-15

    Pure cubic phase, In{sub 2}O{sub 3} nanoparticles with porous structure were synthesized by solid state thermal oxidation of un-irradiated and γ-irradiated indium acetyl acetonate in presence and absence of sodium dodecyl sulphate as surfactant. The as- synthesized In{sub 2}O{sub 3} nanoparticles were characterized by X-ray diffraction (XRD), fourier transformation infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), transition electron microscopy (TEM) and thermogravimetry (TG). The shapes and morphologies of as- synthesized In{sub 2}O{sub 3} nanoparticles were highly affected by γ-irradiation of indium acetyl acetonate precursor and by addition of sodium dodecyl sulphate as surfactant. Calcination of un-irradiated indium acetyl acetonate precursor to 4 hours of 600 °C leads to the formation of spherical- shaped accumulative and merged In{sub 2}O{sub 3} nanoparticles with porous structure, whereas irregular porous architectures composed of pure In{sub 2}O{sub 3} nanoparticles were obtained by using γ-irradiated indium acetylacetonate precursor. The as- prepared In{sub 2}O{sub 3} nano products exhibit photoluminescence emission (PL) property and display thermal stability in a wide range of temperature (25-800 °C) which suggest possible applications in nanoscale optoelectronic devices. (author)

  4. Polyvinyl Acetate Resin as a Binder Effecting Mechanical and CombustionProperties of Combustible Cartridge Case Formulations

    Directory of Open Access Journals (Sweden)

    M.T. Shedge

    2008-05-01

    Full Text Available Several combustible cartridge case (CCC formulations containing nitrocellulose (NC as anenergetic ingredient with diphenylamine (DPA as stabiliser, cellulose fiber as reinforcing materialand polyvinyl acetate (PVAc as a binder are processed to form combustible discs. A formulationcontaining  nitrocellulose (83 parts, cellulose (17 parts , PVAc (20 parts and  diphenylamine(1 part by weight was observed with the improvement of  mechanical properties without anyadverse effect on combustion characteristics, safety parameters and compatibility with triplebase multi-tubular propellant. Dynamic firing performance was also satisfactory.

  5. Extraction and Determination of Quercetin and Myricetin from Chamaecyparis obtusa by Ionic Liquids-based Monolithic Cartridge%Extraction and Determination of Quercetin and Myricetin from Chamaecyparis obtusa by Ionic Liquids-based Monolithic Cartridge

    Institute of Scientific and Technical Information of China (English)

    朱涛; 毕文韬; 卢敬昊

    2011-01-01

    A short ionic liquids (ILs)-based monolithic cartridge was prepared and used as the selective extraction sorbent. After the material was evaluated by field emission-scanning electron microscopy (FE-SEM), a new approach for the extraction and determination of quercetin and myricetin from Chamaecyparis obtusa (C. obtusa) by using ILs-based, monolithic cartridge system was developed. Chromatographic analysis was conducted on a C18 column with UV detection at 372 nm, an eluting solution consisting of acetonitrile-water (25/75, V/V) as the mobile phase, and a flow rate of 0.7 mLomin 1. A good linear relationship was demonstrated when the concentrations of quercetin and myricetin were in the range of 0.5--100.0 ggomL-1. The recoveries ranged from 101.6% to 104.6% and the inter- and intra-day relative standard deviations (RSD) were less than 5.0%. This method effectively removed the impurities and avoided tedious pretreatment. It provided a fast, economic and effective method for assaying trace drugs from natural plants.

  6. 基于MSP430的硒鼓芯片复位装置的设计%Design of Cartridge Chip Reset Device Based on MSP430

    Institute of Scientific and Technical Information of China (English)

    高广; 何美玲; 俎全高; 周敏

    2011-01-01

    Aiming at that the printing supplies for laser toner cartridge manufacturer in the production process are needed to resolve the problem of cartridge chip re-use issues, a cartridge chip reset device based on MSP430 is designed. Different types of toner cartridge chips can be reset by the device, so that the cartridge chips can be recycled in order to achieving production cost savings, protecting the environment. The device also has a good reset effect, the advantages of easy operation.%针对激光打印耗材生产厂家硒鼓生产过程中需对硒鼓芯片进行再利用的问题,设计了一种基于MSP430的硒鼓芯片复位装置.利用该装置可以复位不同型号的硒鼓芯片,从而使硒鼓芯片可循环利用,以达到节约生产成本、保护环境的目的.该装置同时具有复位效果好、易于操作的优点.

  7. Predicting the lifetime of organic vapor cartridges exposed to volatile organic compound mixtures using a partial differential equations model.

    Science.gov (United States)

    Vuong, François; Chauveau, Romain; Grevillot, Georges; Marsteau, Stéphanie; Silvente, Eric; Vallieres, Cécile

    2016-09-01

    In this study, equilibria, breakthrough curves, and breakthrough times were predicted for three binary mixtures of four volatile organic compounds (VOCs) using a model based on partial differential equations of dynamic adsorption coupling a mass balance, a simple Linear Driving Force (LDF) hypothesis to describe the kinetics, and the well-known Extended-Langmuir (EL) equilibrium model. The model aims to predict with a limited complexity, the BTCs of respirator cartridges exposed to binary vapor mixtures from equilibria and kinetics data obtained from single component. In the model, multicomponent mass transfer was simplified to use only single dynamic adsorption data. The EL expression used in this study predicted equilibria with relatively good accuracy for acetone/ethanol and ethanol/cyclohexane mixtures, but the prediction of cyclohexane uptake when mixed with heptane is less satisfactory. The BTCs given by the model were compared to experimental BTCs to determine the accuracy of the model and the impact of the approximation on mass transfer coefficients. From BTCs, breakthrough times at 10% of the exposure concentration t10% were determined. All t10% were predicted within 20% of the experimental values, and 63% of the breakthrough times were predicted within a 10% error. This study demonstrated that a simple mass balance combined with kinetic approximations is sufficient to predict lifetime for respirator cartridges exposed to VOC mixtures. It also showed that a commonly adopted approach to describe multicomponent adsorption based on volatility of VOC rather than adsorption equilibrium greatly overestimated the breakthrough times.

  8. Evaluation of Different Holder Devices for Freeze-Drying in Dual-Chamber Cartridges With a Focus on Energy Transfer.

    Science.gov (United States)

    Korpus, Christoph; Friess, Wolfgang

    2017-04-01

    For freeze-drying in dual-chamber cartridges, a holder device to enable handling and safe positioning in the freeze-dryer is necessary. The aim of this study was to analyze 4 different types of holder devices and to define the best system based on energy transfer. The main criteria were drying homogeneity, ability to minimize the influence of atypical radiation on product temperatures, and heat transfer effectiveness. The shell holder reduced the influence of atypical radiation by almost 60% compared to a block system and yielded the most homogenous sublimation rates. Besides the most efficient heat transfer with values of 1.58E-4 ± 2.06E-6 cal/(s*cm(2)*K) at 60 mTorr to 3.63E-4 ± 1.85E-5 cal/(s*cm(2)*K) at 200 mTorr for Ktot, reaction times to shelf temperature changes were up to 4 times shorter compared to the other holder systems and even faster than for vials. The flexible holder provided a comparable shielding against atypical radiation as the shell but introduced a third barrier against energy transfer. Block and guardrail holder were the least efficient system tested. Hence, the shell holder provided the best radiation shielding, enhanced the transferability of the results to a larger scale, and improved the homogeneity between the dual-chamber cartridges.

  9. Analysis of the Directional Control Loop Based on Cartridge Valve%二通插装阀方向控制回路分析

    Institute of Scientific and Technical Information of China (English)

    石全

    2009-01-01

    Under the development trend of hydraulic system-High pressure and large flux, the cartridge valve is more and more used. Two kinds of directional control loop composed by the Cartridge Valve are analysed in detail in this paper, that have a positive effect on understanding deeply and appalying of the Cartridge Valve.%高压、大流量是液压系统的发展趋势,二通插装阀的应用势必越来越多.本文对2种比较典型的由插装阀组成的方向控制油路进行了比较细致的分析,对加深理解和实际应用插装阀具有一定的参考价值.

  10. Combined supercritical fluid extraction/solid-phase extraction with octadecylsilane cartridges as a sample preparation technique for the ultratrace analysis of a drug metabolite in plasma.

    Science.gov (United States)

    Liu, H; Cooper, L M; Raynie, D E; Pinkston, J D; Wehmeyer, K R

    1992-04-01

    Supercritical fluid extraction was coupled with solid-phase extraction using octadecylsilane cartridges for the selective isolation of ultratrace levels of a drug metabolite, mebeverine alcohol, from plasma. Plasma was directly applied to the extraction cartridge, the cartridge was washed to remove protein and then extracted under supercritical conditions using CO2/5% methanol. The effluent from the extraction cell was bubbled through a small volume of 2-propanol to trap the extracted mebeverine alcohol. The effects of extraction pressure and temperature on analyte recovery were examined. The absolute recovery, selectivity, precision, and accuracy of the combined supercritical fluid extraction/solid-phase extraction approach were compared to those of conventional solid-phase extraction using gas chromatography/mass spectrometry in the selected-ion monitoring mode. Mebeverine alcohol was used as a model compound, and dog plasma was employed as the biological matrix for these studies.

  11. Time since discharge of 9mm cartridges by headspace analysis, part 2: Ageing study and estimation of the time since discharge using multivariate regression.

    Science.gov (United States)

    Gallidabino, M; Romolo, F S; Weyermann, C

    2017-03-01

    Estimating the time since discharge of spent cartridges can be a valuable tool in the forensic investigation of firearm-related crimes. To reach this aim, it was previously proposed that the decrease of volatile organic compounds released during discharge is monitored over time using non-destructive headspace extraction techniques. While promising results were obtained for large-calibre cartridges (e.g., shotgun shells), handgun calibres yielded unsatisfying results. In addition to the natural complexity of the specimen itself, these can also be attributed to some selective choices in the methods development. Thus, the present series of papers aimed to systematically evaluate the potential of headspace analysis to estimate the time since discharge of cartridges through the use of more comprehensive analytical and interpretative techniques. Following the comprehensive optimisation and validation of an exhaustive headspace sorptive extraction (HSSE) method in the first part of this work, the present paper addresses the application of chemometric tools in order to systematically evaluate the potential of applying headspace analysis to estimate the time since discharge of 9mm Geco cartridges. Several multivariate regression and pre-treatment methods were tested and compared to univariate models based on non-linear regression. Random forests (RF) and partial least squares (PLS) proceeded by pairwise log-ratios normalisation (PLR) showed the best results, and allowed to estimate time since discharge up to 48h of ageing and to differentiate recently fired from older cartridges (e.g., less than 5h compared to more than 1-2 days). The proposed multivariate approaches showed significant improvement compared to univariate models. The effects of storage conditions were also tested and results demonstrated that temperature, humidity and cartridge position should be taken into account when estimating the time since discharge.

  12. Forensic Medical Peculiarities of Skin Damage Caused by a Large-Caliber Bullet Cartridge of Traumatic (Non-Lethal) Action “Teren-12P”

    OpenAIRE

    Sapielkin, V. V.

    2016-01-01

    The limitation of the database on the properties of the bullet cartridge of traumatic (non-lethal) action 12-gauge “Teren-12P” as well as the nature and peculiarities of injuries caused by it can lead to certain difficulties in the conduction of the complex forensic examinations when investigating their wide-scale use. Using pig skin and ballistic clay experimental shots from shotgun “Fort-500M” using bullet cartridge “Teren-12P” from a distance of 15 m were carried out. The obtained data wer...

  13. Sensitive determination of fenpropathrin, cyhalothrin and deltamethrin in environmental water samples using multiwalled carbon nanotubes cartridge prior to HPLC

    Institute of Scientific and Technical Information of China (English)

    Qing Xiang Zhou; Guo Hong Xie; Jun Ping Xiao; Wei Dong Wang; Yu Jie Ding

    2008-01-01

    This paper described a new method for the trace determination of fenpropathrin, cyhalothrin and deltamethrin using multiwalledcarbon nanotubes (MWCNTs) cartridge. Important parameters, such as the sample pH, eluent and its volume, sample flow rate andsample volume were investigated in detail. The linear ranges, the detection limits, and precisions (R.S.D.) were in the range of 0.1-40 μg L-1 1.3-4.3 ng L-1 and 2.3-2.8%, respectively. The performance of the proposed method was validated with real watersamples, and the spiked recoveries were in the range of 91.7-117.8%, respectively. The experimental results demonstrated that theproposed method was an excellent alternative for the routine analysis of such pollutants in environmental samples.

  14. Environmental impacts and resource losses of incinerating misplaced household special wastes (WEEE, batteries, ink cartridges and cables)

    DEFF Research Database (Denmark)

    Bigum, Marianne Kristine Kjærgaard; Damgaard, Anders; Scheutz, Charlotte

    2017-01-01

    the misplaced special waste is only 0.5% of residual household waste, it constitutes in the residual household waste the most significant fraction with respect to metal content when iron and aluminum are excluded. By extending the boundary of the LCA beyond the traditional “zero burden boundary”, we were able......The contribution of misplaced special waste (sWEEE, lamps, CRT, batteries, ink cartridges and cables) to environmental impacts from incineration of residual household waste was quantified through life cycle assessment (LCA)-modelling. Misplaced special waste was quantified to constitute less than 1...... and batteries. However as shown by sensitivity analysis, lack of good data on the transfer of rare and hazardous metals to the flue gas in the incineration process should receive further investigation before the environmental impacts from misplaced incinerated special waste can fully be concluded upon. Although...

  15. Efficiency of Polyphenol Extraction from Artificial Honey Using C18 Cartridges and Amberlite® XAD-2 Resin: A Comparative Study

    Directory of Open Access Journals (Sweden)

    Chua Yung An

    2016-01-01

    Full Text Available A comparative study of the extraction efficiency of nine known polyphenols [phenolic acids (benzoic acid, dihydroxybenzoic acid, gallic acid, trans-cinnamic acid, and vanillic acid and flavonoids (naringenin, naringin, quercetin, and rutin] was conducted by deliberately adding the polyphenols to an artificial honey solution and performing solid phase extraction (SPE. Two SPE methods were compared: one using Amberlite XAD-2 resin and another one using a C18 cartridge. A gradient high performance liquid chromatography system with an RP18 column and photodiode array detector was utilized to analyze the extracted polyphenols. The mean percent of recovery from the C18 cartridges was 74.2%, while that from the Amberlite XAD-2 resin was 43.7%. The recoveries of vanillic acid, naringin, and rutin were excellent (>90%; however, gallic acid was not obtained when C18 cartridges were used. Additionally, the reusability of Amberlite XAD-2 resin was investigated, revealing that the mean recovery of polyphenols decreased from 43.7% (1st extraction to 29.3% (3rd extraction. It was concluded that although Amberlite XAD-2 resin yielded a higher number of compounds, C18 cartridges gave a better extraction recovery. The lower recovery seen for the Amberlite XAD-2 resin also cannot be compensated by repeated extractions due to the gradual decrease of extraction recovery when reused.

  16. Time since discharge of 9mm cartridges by headspace analysis, part 1: Comprehensive optimisation and validation of a headspace sorptive extraction (HSSE) method.

    Science.gov (United States)

    Gallidabino, M; Romolo, F S; Weyermann, C

    2017-03-01

    Estimating the time since discharge of spent cartridges can be a valuable tool in the forensic investigation of firearm-related crimes. To reach this aim, it was previously proposed that the decrease of volatile organic compounds released during discharge is monitored over time using non-destructive headspace extraction techniques. While promising results were obtained for large-calibre cartridges (e.g., shotgun shells), handgun calibres yielded unsatisfying results. In addition to the natural complexity of the specimen itself, these can also be attributed to some selective choices in the methods development. Thus, the present series of paper aimed to more systematically evaluate the potential of headspace analysis to estimate the time since discharge of cartridges through the use of more comprehensive analytical and interpretative techniques. Specifically, in this first part, a method based on headspace sorptive extraction (HSSE) was comprehensively optimised and validated, as the latter recently proved to be a more efficient alternative than previous approaches. For this purpose, 29 volatile organic compounds were preliminary selected on the basis of previous works. A multivariate statistical approach based on design of experiments (DOE) was used to optimise variables potentially involved in interaction effects. Introduction of deuterated analogues in sampling vials was also investigated as strategy to account for analytical variations. Analysis was carried out by selected ion mode, gas chromatography coupled to mass spectrometry (GC-MS). Results showed good chromatographic resolution as well as detection limits and peak area repeatability. Application to 9mm spent cartridges confirmed that the use of co-extracted internal standards allowed for improved reproducibility of the measured signals. The validated method will be applied in the second part of this work to estimate the time since discharge of 9mm spent cartridges using multivariate models.

  17. Scale-up of Sterilizing-grade Membrane Filters from Discs to Pleated Cartridges: Effects of Operating Parameters and Solution Properties.

    Science.gov (United States)

    Kumar, Anil; Martin, Jerold; Kuriyel, Ralf

    2015-01-01

    For direct flow sterilizing-grade filtration, a linear scale-up between the performance of discs and pleated filter cartridges has traditionally been assumed. Linear scale-up assumes that the filtration performances, defined here as filter flux and capacity, scale linearly with the membrane area and remains independent of the selected device formats. However, experimental results show that the later assumption does not hold in all cases. In this article, we investigated the effect of solution properties and operating parameters on scale-up with both fouling and non-fouling feeds. For non-fouling solutions, such as buffers, the flux ratio, defined as α, between pleated filter cartridges and disc filters range from 0.5 to 0.85. For complex fouling feeds, such as protein or cell culture media solutions, the ratio of initial flux between pleated filter cartridges and discs was the same as the flux ratio, α. For fouling solutions, the ratio of filtration capacity between pleated cartridges and discs, referred to as capacity ratio, β, was variable. We found that β was sensitive to the particle size distribution of the challenge solution and the mode of filtration operation (constant pressure or constant flux), whereas it was less sensitive to the magnitude of the operating pressure or flux and concentration of the fouling species. For most conditions tested, β among pleated cartridges and discs was within ±20% variation of unity. At the end, we present a modified standard model that accounts for both variations in flux ratio, α, as well as capacity ratios, β, for estimating the requirement for membrane area at manufacturing scale with proteinacious fouling and non-protein/non-fouling feeds. The data show that for cases where filtration is capacity controlled, flux ratios between the pleated filter and disc are not critical. For such cases, the use of a high-area laid-over pleated cartridge construction allows for reducing the number of 10 inch pleated filter

  18. Randomized Comparison of Two Vaginal Self-Sampling Methods for Human Papillomavirus Detection: Dry Swab versus FTA Cartridge.

    Directory of Open Access Journals (Sweden)

    Rosa Catarino

    Full Text Available Human papillomavirus (HPV self-sampling (self-HPV is valuable in cervical cancer screening. HPV testing is usually performed on physician-collected cervical smears stored in liquid-based medium. Dry filters and swabs are an alternative. We evaluated the adequacy of self-HPV using two dry storage and transport devices, the FTA cartridge and swab.A total of 130 women performed two consecutive self-HPV samples. Randomization determined which of the two tests was performed first: self-HPV using dry swabs (s-DRY or vaginal specimen collection using a cytobrush applied to an FTA cartridge (s-FTA. After self-HPV, a physician collected a cervical sample using liquid-based medium (Dr-WET. HPV types were identified by real-time PCR. Agreement between collection methods was measured using the kappa statistic.HPV prevalence for high-risk types was 62.3% (95%CI: 53.7-70.2 detected by s-DRY, 56.2% (95%CI: 47.6-64.4 by Dr-WET, and 54.6% (95%CI: 46.1-62.9 by s-FTA. There was overall agreement of 70.8% between s-FTA and s-DRY samples (kappa = 0.34, and of 82.3% between self-HPV and Dr-WET samples (kappa = 0.56. Detection sensitivities for low-grade squamous intraepithelial lesion or worse (LSIL+ were: 64.0% (95%CI: 44.5-79.8 for s-FTA, 84.6% (95%CI: 66.5-93.9 for s-DRY, and 76.9% (95%CI: 58.0-89.0 for Dr-WET. The preferred self-collection method among patients was s-DRY (40.8% vs. 15.4%. Regarding costs, FTA card was five times more expensive than the swab (~5 US dollars (USD/per card vs. ~1 USD/per swab.Self-HPV using dry swabs is sensitive for detecting LSIL+ and less expensive than s-FTA.International Standard Randomized Controlled Trial Number (ISRCTN: 43310942.

  19. A portable lab-on-a-chip instrument based on MCE with dual top-bottom capacitive coupled contactless conductivity detector in replaceable cell cartridge.

    Science.gov (United States)

    Ansari, Kambiz; Ying, Jasmine Yuen Shu; Hauser, Peter C; de Rooij, Nico F; Rodriguez, Isabel

    2013-05-01

    A new design for a compact portable lab-on-a-chip instrument based on MCE and dual capacitively coupled contactless conductivity detection (dC(4) D) is described. The instrument is battery powered with total dimension of 14 × 25 × 8 cm(3) (w × l × h), and weighs 1.2 kg. The device consists of a front electrophoresis compartment which has the chip holder and the chip, the associated high-voltage electrodes for electrophoresis injection and separation and the detector. The detection cell is integrated into the device housing with an exchangeable plug-and-play cartridge format. The design of the dC(4) D cell has been optimized for maximum performance. The cartridge includes the top-bottom excitation and pick up electrodes incorporated into the cell and connected to push-pull self-latching pins that are insulated with plastic. The metal frame of the cartridge is grounded completely to eliminate electronic interferences. The cartridge is designed to clamp a thin fluidic chip at the detection point. The cartridges are replaceable whereby different cartridges have different detection electrode configurations to employ according to the sensitivity or resolution needed in the specific analytical application. The second compartment consists of all the electronics, data acquisition card, high-voltage modules of up to ±5 kV both polarity, and batteries for 10 h of operation. The improved detector performance is illustrated by the electrophoresis analysis of six cations (NH4 (+) , K(+) , Ca(2+) , Na(+) , Mg(2+) , Li(+) ) with a detection limit of approximately 5 μM and the analysis of the anions (Br(-) , Cl(-) , NO2 (-) , NO3 (-) , SO4 (2-) , F(-) ) with a detection limit of about 3 μM. Analytical capabilities of the instrument for food and medical applications were evaluated by simultaneous detection of organic and inorganic acids in fruit juice and inorganic cations and anions in rabbit blood samples and human urine samples are also demonstrated.

  20. Study of the aerobic contamination of four disposable materials (anesthetic cartridge, saliva ejector tip, gutta percha and cotton roll

    Directory of Open Access Journals (Sweden)

    Ashofteh Yazdi K.

    2005-06-01

    Full Text Available Statement of Problem: Today, cross infection control is an integral part of dentistry and many dental health care workers no longer question its necessity. All dental equipments and instruments could be potentially considered as a source of infection. Purpose: The aim of this study was the evaluation of aerobic contaminations of four disposable materials used in routine dental practice. Materials and Methods: In this cross-sectional study, random sampling was performed and tryptone soy broth transfer culture medium was used. After 24 hours of incubation, samples were transferred to specific culture media. (Mckangy, Chocolate agar and Blood agar. Cultured bacteria were stained and studied using gram staining method. The study was carried out in a 17 weeks period. Results: All suction tips were infected with Bacillus cereus bacterium. Two cases of cotton roll samples showed contamination with Bacillus cereus, 2 cases with gram positive, coagulase negative cocci, 1 case with Streptococcus viridians and one case with Enterobacter class A. One case of anesthetic cartridges was contaminated with Staphylococcus epidermidis and two cases with Streptococcus viridians. Two cases of gutta-percha samples were contaminated with Bacillus cereus. Conclusion: Based of the findings of this study, the highest level of contamination was observed in saliva ejector tips. Contamination with Bacillus cereus was seen more frequently.

  1. Preparation of amino-modified active carbon cartridges and their use in the extraction of quercetin from Oldenlandia diffusa.

    Science.gov (United States)

    Zhu, Tao; Row, Kyung Ho

    2011-12-05

    Polyethyleneimine (PEI) and ethylenediamine (EDA) as modifiers were bonded on active carbon (AC) surface for specific selective extraction of quercetin from Oldenlandia diffusa. The characteristics of the modified AC materials that were obtained were investigated by field emission-scanning electron microscopy (FE-SEM) and Fourier transform infrared spectrometer (FT-IR). The interactions between quercetin and the AC materials were investigated by fitting the static adsorption data to four linear and nonlinear adsorption isotherm models. Of these four models, the Langmuir-Freundlich adsorption isotherm was proved the best for investigating quercetin on AC materials. Scatchard analysis was used to evaluate the binding properties of the AC materials for quercetin. Solvent extraction and solid-phase extraction (SPE) were optimized, and the effect of the mobile phase pH was investigated to improve the performance for the separation of quercetin on high performance liquid chromatography (HPLC). The results from the validation of the proposed analytical method demonstrated that the EDA-modified AC was the most suitable SPE cartridge for the purification of quercetin from O. diffusa. Copyright © 2011 Elsevier B.V. All rights reserved.

  2. Side-by-side comparison of disposable microchips with commercial capillary cartridges for application in capillary isoelectric focusing with whole column imaging detection.

    Science.gov (United States)

    Liu, Zhen; Ou, Junjie; Samy, Razim; Glawdel, Tomasz; Huang, Tiemin; Ren, Carolyn L; Pawliszyn, Janusz

    2008-10-01

    Simple-structured, well-functioned disposable poly(dimethylsiloxane) (PDMS) microchips were developed for capillary isoelectric focusing with whole column imaging detection (CIEF-WCID). Side-by-side comparison of the developed microchips with well-established commercial capillary cartridges demonstrated that the disposable microchips have comparable performance as well as advantages such as absence of lens effect and possibility of high-aspect-ratio accompanied with a dramatic reduction in cost.

  3. Efficiency of Polyphenol Extraction from Artificial Honey Using C18 Cartridges and Amberlite® XAD-2 Resin: A Comparative Study

    OpenAIRE

    Chua Yung An; Md. Murad Hossain; Fahmida Alam; Md. Asiful Islam; Md. Ibrahim Khalil; Nadia Alam; Siew Hua Gan,

    2016-01-01

    A comparative study of the extraction efficiency of nine known polyphenols [phenolic acids (benzoic acid, dihydroxybenzoic acid, gallic acid, trans-cinnamic acid, and vanillic acid) and flavonoids (naringenin, naringin, quercetin, and rutin)] was conducted by deliberately adding the polyphenols to an artificial honey solution and performing solid phase extraction (SPE). Two SPE methods were compared: one using Amberlite XAD-2 resin and another one using a C18 cartridge. A gradient high perfor...

  4. Research into Radar Multi-station Joint Movement Against Chaff Cartridge Jamming%雷达多站联动抗箔条弹干扰研究

    Institute of Scientific and Technical Information of China (English)

    曹志宏; 张新星; 刁华伟

    2012-01-01

    Though analyzing the jamming area of single chaff cartridge,this paper educes that the is definite blind zone when aircrafts launch chaff cartridges backwards,analyzes the feasibility th deploying the fire control radar in the blind zone to raise the anti-chaff cartridge jamming capabili re at ty of radar,demonstrates the rationality of using multi-station joint movement to confront the chaff catridge jamming,which has much help for advancing the combat efficiency of fire control radars.%通过对单枚箔条弹的干扰区进行分析,得出飞机后向发射箔条弹时存在一定的盲区,分析了在此盲区中部署火控雷达对提高雷达的反箔条弹干扰能力的可行性,验证了在此种情况下依靠多站联动抗箔条弹干扰的合理性,对提高火控雷达的作战效能有很大的帮助。

  5. Monitoring of the radiocesium in river water in Fukushima using rapid and simultaneous monitoring of particulate and dissolved radiocesium in water with nonwoven fabric cartridge filters

    Energy Technology Data Exchange (ETDEWEB)

    Tsuji, H.; Yasutaka, T. [National Institute of Advanced Industrial Science and Technology (Japan); Kondo, Y. [Japan Vilene Company, Ltd (Japan); Suzuki, Y. [Fukushima Agricultural Technology Centre (Japan)

    2014-07-01

    The environmental monitoring of dissolved and particulate radiocesium in river became important after the accident of TEPCO Fukushima Daiichi Nuclear Power Plant. Traditional monitoring methods, such as evaporative concentration, require time for pre-processing because the concentration of dissolved radiocesium of river water in Fukushima prefecture is currently very low, averagely 0.001 - 0.1 Bq/L. Our research group has developed a monitoring method to investigate the radiocesium concentration in water by each existence form. Yasutaka et al. (2013) and Tsuji et al.(2013) developed a method for rapid and simultaneous monitoring of particulate and dissolved radiocesium in water with nonwoven fabric cartridge filters. This method uses pleated polypropylene nonwoven fabric filter with a pore size of 1-μm to collect particulate radiocesium, and nonwoven fabric impregnated with Prussian blue (PB) to absorb dissolved radiocesium. The fabric was placed into cylindrical plastic cartridges (SS-cartridge and PB-cartridge). This method could catch the 99% of the suspended solid (SS) and absorb 95% of dissolved radiocesium separately in 20 L water within 40 minutes. This device was applied to monitor the water in Abukuma River (January 2013) and upper area of Kuchibuto river (May 2013) at 12 locations, and the results were compared with those obtained by the filtrating and evaporative concentration method. The SS concentration and radioactivity of SS in the Abukuma river water, calculated by weight gain of the SS-cartridge and by sediment weight after filtration with a 0.45-μm membrane filter, agreed well without one location.The radioactivity of the dissolved {sup 137}Cs also agreed well between these two methods. In the Abukuma River, dissolved {sup 137}Cs was 0.006-0.025 Bq/L and particulate {sup 137}Cs was 0.008-0.070 Bq/L by the presented method in January 2013. In addition, the required time for pre-processing was reduced by more than 10 times that by filtrating and

  6. The new INNOVANCE® PFA P2Y cartridge is sensitive to the detection of the P2Y₁₂ receptor inhibition.

    Science.gov (United States)

    Koessler, Juergen; Kobsar, Anna L; Rajkovic, Mirjana S; Schafer, Andreas; Flierl, Ulrike; Pfoertsch, Stephanie; Bauersachs, Johann; Steigerwald, Udo; Rechner, Andreas R; Walter, Ulrich

    2011-01-01

    Insufficient response on antiplatelet medication has become an intensively discussed issue because of the risk factor of recurrent adverse cardiovascular events. However, the monitoring of antiplatelet therapy requires appropriate, robust and reliable test methods. For the measurement of thienopyridine effects, the manufacturer of the PFA-100® System provides the INNOVANCE® PFA P2Y * cartridge. We tested this cartridge for its capacity to detect the inhibition of the P2Y₁₂ receptor, which is the target for thienopyridine medication (e.g. clopidogrel). We compared the INNOVANCE® PFA P2Y * results with those obtained by the receptor specific flow cytometric vasodilator stimulated phosphoprotein (VASP) assay that expresses the status of the P2Y₁₂ receptor as "platelet reactivity index" (PRI). The in vitro addition of the P2Y₁₂ receptor antagonist cangrelor (AR-C69931MX) to citrated human whole blood resulted in a dose-dependent prolongation of closure times (CTs) of the INNOVANCE® PFA P2Y * cartridge correlating with decreased PRI levels. In volunteers, the intake of a 600 mg clopidogrel loading dose caused an increase of the CTs in all volunteers, although some of these volunteers were identified as "poor responders" by the VASP assay (no significant reduction of PRI levels). In 50 patients with stable coronary artery disease undergoing percutaneous coronary intervention (PCI) and under dual antiplatelet therapy, the new cartridge had a detection rate of 84% (CT 106 s as cut-off) for clopidogrel medication. After dividing the 50 patients into two groups according to their response to clopidogrel INNOVANCE® PFA P2Y * recognized all "responders" (defined by a PRI > 50%) using >106 s as cut-off but the specificity for a "good response" was only 42% because several "poor responders" (defined by a PRI > 50%) also showed CTs above the cut-off. The best correlation (substantial agreement) between the results of INNOVANCE® PFA P2Y * and of the VASP

  7. Quantitative analysis of four protein biomarkers: An automated microfluidic cartridge-based method and its comparison to colorimetric ELISA.

    Science.gov (United States)

    Dysinger, Mark; Marusov, Greg; Fraser, Stephanie

    2017-09-13

    Biomarker quantitation with ligand binding assays has matured greatly in recent years. This maturation has been partly in response to demands for more data points from fewer samples or less available sample volume. Multiplexing offers opportunities to acquire data for multiple analytes from single sample assay iterations, but has its own unique challenges and limitations. ProteinSimple has developed Simple Plex™, an automated immunoassay platform consisting of microfluidic cartridge-based assays run on the Ella instrument. Ella subverts traditional multiplexing challenges by rapidly performing triplicate measurements of up to four different analytes simultaneously, each in their own respective assay vessels and all from a single sample. Here we describe a comparison of the Simple Plex platform versus colorimetric ELISA and their respective abilities to quantitate four common biomarkers (MCP-1/CCL2, VEGF-A, TNF-α, and IL-6) from twenty-eight healthy individual donor plasma samples. Each biomarker was tested on the two platforms on each of two days. Ella analysis required significantly reduced sample volume, manual steps, and total time. Overall, Ella was able to quantify results for all twenty-eight samples for each of the four biomarkers. In contrast, ELISA was able to measure quantifiable results within respective calibration curve ranges for MCP-1/CCL2 (96% of samples) and VEGFA (7% of samples). For TNF-α and IL-6, ELISA was not sensitive enough to quantify any samples in the assay ranges. This stark difference in quantitative results underscores Ella's ability to multiplex without compromising sensitivity, and has far reaching potential for biomarker panel measurement in support of diagnosis, prognosis, and monitoring of disease. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. Determination of closantel residues in milk and animal tissues by HPLC with fluorescence detection and SPE with oasis MAX cartridges.

    Science.gov (United States)

    Sun, Han-Wen; Wang, Feng-Chi; Ai, Lian-Feng

    2008-04-01

    A liquid chromatographic method for the determination of closantel residues in milk and tissues is developed and validated. An acetonitrile-acetone solution (80:20, v/v) is used for the extraction of closantel residues from milk and animal tissues, and the extract is purified by solid-phase extraction with Oasis MAX cartridges and a mixture of formic acid-acetonitrile (5:95, v/v) as the elution solution. A C(18) bonded silica column is used for chromatographic separation. The mobile phase consists of acetonitrile-water (85:15, v/v) containing 0.05% triethylamine at pH 2.5, adjusted with phosphoric acid with the flow-rate set at 1.0 mL/min. Using the fluorescence emission of closantel at lambda(ex) = 335 nm and lambda(ex) = 510 nm, the calibration curve is linear, with a correlation coefficient of 0.9999 over the concentration range of 10-5000 microg/kg for the tissue sample and 10-5000 microg/L for the milk sample. The detection limit (s/n = 3) is 3 microg/kg for tissue sample and 3 microg/L for milk sample. The intra- and inter-day repeatabilities are between 3.35-7.66% and 4.04-8.67%, respectively. The proposed method enables the quantitative determination of closantel residues at levels as low as 10 microg/kg in animal tissue samples and 10 microg/L in milk samples.

  9. Proteoglycan from salmon nasal cartridge promotes in vitro wound healing of fibroblast monolayers via the CD44 receptor

    Energy Technology Data Exchange (ETDEWEB)

    Ito, Gen; Kobayashi, Takeshi; Takeda, Yoshie [Department of Physiology, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550 (Japan); Sokabe, Masahiro, E-mail: msokabe@med.nagoya-u.ac.jp [Department of Physiology, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550 (Japan); Mechanobiology Laboratory, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550 (Japan); Mechanobiology Institute Singapore, National University of Singapore, Singapore 117411 (Singapore)

    2015-01-16

    Highlights: • Proteoglycan from salmon nasal cartridge (SNC-PG) promoted wound healing in fibroblast monolayers. • SNC-PG stimulated both cell proliferation and cell migration. • Interaction between chondroitin sulfate-units and CD44 is responsible for the effect. - Abstract: Proteoglycans (PGs) are involved in various cellular functions including cell growth, adhesion, and differentiation; however, their physiological roles are not fully understood. In this study, we examined the effect of PG purified from salmon nasal cartilage (SNC-PG) on wound closure using tissue-cultured cell monolayers, an in vitro wound-healing assay. The results indicated that SNC-PG significantly promoted wound closure in NIH/3T3 cell monolayers by stimulating both cell proliferation and cell migration. SNC-PG was effective in concentrations from 0.1 to 10 μg/ml, but showed much less effect at higher concentrations (100–1000 μg/ml). The effect of SNC-PG was abolished by chondroitinase ABC, indicating that chondroitin sulfates (CSs), a major component of glycosaminoglycans (GAGs) in SNC-PG, are crucial for the SNC-PG effect. Furthermore, chondroitin 6-sulfate (C-6-S), a major CS of SNC-PG GAGs, could partially reproduce the SNC-PG effect and partially inhibit the binding of SNC-PG to cells, suggesting that SNC-PG exerts its effect through an interaction between the GAGs in SNC-PG and the cell surface. Neutralization by anti-CD44 antibodies or CD44 knockdown abolished SNC-PG binding to the cells and the SNC-PG effect on wound closure. These results suggest that interactions between CS-rich GAG-chains of SNC-PG and CD44 on the cell surface are responsible for the SNC-PG effect on wound closure.

  10. A comparison of surface topography characterization technologies for use in comparing spent bullet and cartridge case signatures

    Energy Technology Data Exchange (ETDEWEB)

    Batishko, C.R.; Hickman, B.J.; Cuta, F.M.

    1992-11-01

    The Pacific Northwest Laboratory was tasked by the US Department of Energy to provide technical assistance to the Federal Bureau of Investigation in evaluating and ranking technologies potentially useful in high-speed comparison of unique spent bullet and cartridge case surface signatures. Information sources included vendor input, current relevant literature, vendor phone contacts, other FBI resources, relevant PNL reports, and personal contact with numerous PNL technical staff. A comprehensive list of technologies was reduced to a list of 38 by grouping very similar methodologies, and further reduced to a short list of six by applying a set of five minimum functional requirements. A total of 14 primary criteria, many having secondary criteria, were subsequently used to evaluate each technology. The ranked short list results are reported and supported in this document, and their scores normalized to a hypothetical ideal system are as follows: (1) confocal microscopy 82.13; (2) laser dynamic focusing 72.04; (3)moire interferometry V70.94; (4)fringe field capacitance;(5)laser triangulation 66.18; (6)structured/sectioned light 65.55. Information available within the time/budget constraints which was used for the evaluation and ranking was not sufficiently detailed to evaluate specific implementations of the technologies. Each of the technologies in the short list was judged potentially capable of meeting the minimum requirements. Clever, novel engineering solutions resulting in a more cost-effective system, or a closer fit to the ``ideal system,`` could result in a reordering of the short list when actual technical proposals are evaluated. Therefore, it is recommended that a Request for Proposal not be limited to only the highest ranked technology, but include all six technologies in the short list.

  11. A comparison of surface topography characterization technologies for use in comparing spent bullet and cartridge case signatures

    Energy Technology Data Exchange (ETDEWEB)

    Batishko, C.R.; Hickman, B.J.; Cuta, F.M.

    1992-11-01

    The Pacific Northwest Laboratory was tasked by the US Department of Energy to provide technical assistance to the Federal Bureau of Investigation in evaluating and ranking technologies potentially useful in high-speed comparison of unique spent bullet and cartridge case surface signatures. Information sources included vendor input, current relevant literature, vendor phone contacts, other FBI resources, relevant PNL reports, and personal contact with numerous PNL technical staff. A comprehensive list of technologies was reduced to a list of 38 by grouping very similar methodologies, and further reduced to a short list of six by applying a set of five minimum functional requirements. A total of 14 primary criteria, many having secondary criteria, were subsequently used to evaluate each technology. The ranked short list results are reported and supported in this document, and their scores normalized to a hypothetical ideal system are as follows: (1) confocal microscopy 82.13; (2) laser dynamic focusing 72.04; (3)moire interferometry V70.94; (4)fringe field capacitance;(5)laser triangulation 66.18; (6)structured/sectioned light 65.55. Information available within the time/budget constraints which was used for the evaluation and ranking was not sufficiently detailed to evaluate specific implementations of the technologies. Each of the technologies in the short list was judged potentially capable of meeting the minimum requirements. Clever, novel engineering solutions resulting in a more cost-effective system, or a closer fit to the ideal system,'' could result in a reordering of the short list when actual technical proposals are evaluated. Therefore, it is recommended that a Request for Proposal not be limited to only the highest ranked technology, but include all six technologies in the short list.

  12. Are adrenaline autoinjectors fit for purpose? A pilot study of the mechanical and injection performance characteristics of a cartridge- versus a syringe-based autoinjector

    Directory of Open Access Journals (Sweden)

    Andreas Schwirtz

    2010-11-01

    Full Text Available Andreas Schwirtz, Harald SeegerPharma Consult GmbH, Vienna, AustriaBackground: Adrenaline autoinjectors (AAIs are prescribed to facilitate the intramuscular administration of adrenaline in patients diagnosed with life-threatening anaphylaxis. This pilot study investigated the injection and functional properties of two AAIs (deploying different delivery systems under standard conditions, after dynamic and mechanical stresses, and in the presence of denim.Methods: The differences between a cartridge-based AAI (EpiPen® Junior and a syringe-based AAI (Anapen® Junior were assessed using three sets of tests. Test 1: under standard conditions, the injection depth and dose were measured in ballistic gelatine (a validated tissue simulant. Test 2: before the safety cap removal and activation forces were measured, AAIs were subjected to either of two preconditioning tests: 1 free-fall drop test; or 2 static load (ie, 400 N, equivalent to 40 kg weight test; or 3 no preconditioning. Test 3: under standard conditions, injection properties into ballistic gelatine in the presence and absence of denim were investigated. Statistical analyses were performed using the Student’s t-test or Welch’s test.Results: The maximum depth of delivery was significantly greater with cartridge AAI (n = 4, mean 21.09 ± 2.54 mm than with syringe AAI (n = 5; mean 11.64 ± 0.80 mm; P = 0.003. After 2.5 seconds, cartridge AAI (n = 4 discharged significantly more dose than syringe AAI (n = 3; 74.3% versus 25.7% of total dose; P = 0.001. Both cartridge and syringe AAI withstood the free-fall drop test, but almost all devices failed to activate following the static load test. Under standard conditions, significantly less force was required to remove the safety cap of cartridge AAI than syringe AAI (both n = 15; mean 9.56 ± 2.36 N versus 20.23 ± 6.61 N, respectively; P < 0.001, but a significantly greater activation force was required for cartridge AAI than syringe AAI (mean 23

  13. Usefulness of the INNOVANCE PFA P2Y test cartridge for the detection of patients with congenital defects of the platelet P2Y₁₂ receptor for adenosine diphosphate.

    Science.gov (United States)

    Scavone, Mariangela; Germanovich, Ksenia; Femia, Eti A; Cattaneo, Marco

    2014-02-01

    The platelet function analyzer (PFA)-100 is used in clinical practice to screen patients with bleeding diathesis and suspected defects of primary hemostasis. A new cartridge, INNOVANCE PFA P2Y, has been specifically developed to monitor patients' response to drugs inhibiting the platelet P2Y₁₂ receptor for ADP. In this study, we compared the ability of INNOVANCE PFA P2Y to detect congenital defects of the platelet P2Y₁₂ receptor to that of standard cartridge formulations currently in clinical use. We studied two patients with severe P2Y₁₂ deficiency, one patient with heterozygous P2Y₁₂ deficiency and one with dysfunctional P2Y₁₂ receptor. Closure times were measured using 3 cartridges: collagen/ADP, collagen/epinephrine, and INNOVANCE PFA P2Y. The results obtained in the four patients with P2Y₁₂ defects were compared to those obtained for 20 healthy controls. In 2 patients with severe P2Y₁₂ deficiency, closure times of INNOVANCE PFA P2Y and collagen/ADP cartridges were >300 s, while those of collagen/epinephrine cartridge were variable (186s and >300 s). In the patient with dysfunctional P2Y₁₂, closure time of INNOVANCE PFA P2Y was >300 s, while closure times of collagen/ADP and collagen/epinephrine were normal. Closure times of all cartridges were normal in the patient with heterozygous P2Y₁₂ deficiency. Our study provides the first evidence that INNOVANCE PFA P2Y cartridge is sensitive to congenital severe and moderate defects of the platelet P2Y₁₂ receptors. Copyright © 2013 Elsevier Ltd. All rights reserved.

  14. The Cartridge Theory: a description of the functioning of horizontal subsurface flow constructed wetlands for wastewater treatment, based on modelling results.

    Science.gov (United States)

    Samsó, Roger; García, Joan

    2014-03-01

    Despite the fact that horizontal subsurface flow constructed wetlands have been in operation for several decades now, there is still no clear understanding of some of their most basic internal functioning patterns. To fill this knowledge gap, on this paper we present what we call "The Cartridge Theory". This theory was derived from simulation results obtained with the BIO_PORE model and explains the functioning of urban wastewater treatment wetlands based on the interaction between bacterial communities and the accumulated solids leading to clogging. In this paper we start by discussing some changes applied to the biokinetic model implemented in BIO_PORE (CWM1) so that the growth of bacterial communities is consistent with a well-known population dynamics models. This discussion, combined with simulation results for a pilot wetland system, led to the introduction of "The Cartridge Theory", which states that the granular media of horizontal subsurface flow wetlands can be assimilated to a generic cartridge which is progressively consumed (clogged) with inert solids from inlet to outlet. Simulations also revealed that bacterial communities are poorly distributed within the system and that their location is not static but changes over time, moving towards the outlet as a consequence of the progressive clogging of the granular media. According to these findings, the life-span of constructed wetlands corresponds to the time when bacterial communities are pushed as much towards the outlet that their biomass is not anymore sufficient to remove the desirable proportion of the influent pollutants. Copyright © 2013 Elsevier B.V. All rights reserved.

  15. Design of a new cartridge for selective solid phase extraction using molecularly imprinted polymers: selective extraction of theophylline from human serum samples.

    Science.gov (United States)

    Khorrami, Afshin Rajabi; Rashidpur, Amene

    2009-11-15

    This paper describes design of a new cartridge for selective solid phase extraction (SPE) using molecularly imprinted polymers (MIPs). The apparatus which is termed solvent extraction-MISPE (SE-MISPE) cartridge, consisted of a modified conventional micro test tube and has been developed to perform simultaneous forward-extraction of analyte from aqueous sample solution to an organic phase and back-extraction to MIP solid phase. In order to evaluate the performance of the proposed method, extraction of theophylline (THP) from human serum sample was investigated. An appropriate amount of THP-imprinted polymer was placed in the bottom of the micro tube and an organic solvent pipetted onto it and left to swell the polymer completely. A polyethylene frit to secure MIP particles was positioned by two Teflon rings such that it was fixed below the level of the organic layer. Then, aqueous sample solution containing THP was layered over the organic phase and the lid was closed. After completion of extraction, the organic and aqueous phases were removed and the adsorbed analyte was desorbed using a polar organic solvent. In order to reach the highest recovery, the experimental parameters such as the type of organic solvent, pH and ionic strength of aqueous phase, organic to aqueous volume ratio, time of extraction, type and amount of desorbent solvent were optimized. Under the experimental conditions, a plot of HPLC peak areas vs. initial concentrations of THP in the concentration interval of 0.5-30 microg ml(-1) showed a good linearity (r=0.9974). The limit of detection (LOD) and limit of quantification (LOQ) based on three and ten times of the noise of HPLC profile were 0.09 and 0.3 microg ml(-1), respectively. The relative standard deviation (RSD) of the proposed method for the extraction and determination of 5 microg THP from 200 microl standard sample solution for 3 replicate measurements was 3.5%. The results showed that by means of the proposed cartridge, THP could

  16. Integrated quality control: implementation and validation of instrument function checks and procedural controls for a cartridge-based point-of-care system for critical care analysis.

    Science.gov (United States)

    D'Orazio, Paul; Mansouri, Sohrab

    2013-03-01

    In this article, the process used to develop and validate an integrated quality-control system for a cartridge-based, point-of-care system for critical care analysis is outlined. Application of risk management principles has resulted in a quality control system using a combination of statistical quality control with onboard reference solutions and failure pattern recognition used to flag common failure modes during the analytical phase of the testing process. A combination of traditional external quality control, integrated quality control to monitor ongoing instrument functionality, operator training, and other laboratory-implemented monitors is most effective in controlling known failure modes during the testing process.

  17. The stability of non-ionic surfactants and linear alkylbenzene sulfonates in a water matrix and on solid-phase extraction cartridges.

    Science.gov (United States)

    Petrović, M; Barceló, D

    2000-12-01

    The stability of nonylphenol ethoxylates (NPEO), alcohol ethoxylates (AEO), coconut diethanol amides (CDEA) and linear alkylbenzene sulfonates (LAS) in a water matrix and preconcentrated on SPE cartridges was studied. A stability study was carried out in a water matrix (spiked ground water and real-world waste water) comparing different pretreatment procedures (addition of sulfuric acid to pH = 3, preservation with 1% and 3% of formaldehyde). When stored in a water matrix serious qualitative and quantitative changes occurred in waste water during the period of time studied (30 days). The losses of C12-C14 alcohol ethoxylates ranged from 72% to 88% when the sample was preserved with acid and from 17% to 86% when the sample was preserved with formaldehyde (3%). Simultaneously, an enrichment of the shorter alkyl chain homologues (C7EO and C10EO) was observed. The losses of NPEO were from 45% (sample preserved by acidification or by addition of 3% of formaldehyde) to 85% (sample preserved with 1% of formaldehyde). Additionally, an increase in concentration of polyethylene glycols (PEGs) and formation of different acidic forms, such as monocarboxylated (MCPEGs) and dicarboxylated polyethylene glycols (DCPEGs) were observed. The stability of surfactants preconcentrated on SPE cartridges was studied as a function of storage time and storage conditions (room temperature, 4 degrees C and -20 degrees C). The results indicate that disposable SPE cartridges can be recommended for the stabilization of non-ionic surfactants and LAS. Storage at -20 degrees C is feasible for long periods (up to 3 months for ground water and up to 2 months for waste water), while storage at 4 C can be recommended for a maximum of 1 month. When cartridges were kept at -20 degrees C the losses of AEOs (n = 12, 13 and 14), preconcentrated from waste water, ranged from 17 to 29% (after 60 days) and other compounds suffered small losses (maximum of 14% for C13LAS). At room temperature, after 7 days, the

  18. Selective and Accurate Determination Method of Propofol in Human Plasma by Mixed-Mode Cation Exchange Cartridge and GC-MS

    Directory of Open Access Journals (Sweden)

    Jae Sung Pyo

    2016-01-01

    Full Text Available A gas chromatography-mass spectrometry (GC-MS method for the determination of propofol in human plasma has been developed and validated. Propofol was extracted from human plasma by using mixed-mode cation exchange/reversed-phase (MCX cartridges. As propofol easily volatilizes during concentration, 100% methanol was injected directly into GC-MS to elute propofol. Despite avoiding concentration process of the eluted solution, lower limit of quantization (LLOQ of propofol was 25 ng/mL. The validated method exhibited good linearity (R2=0.9989 with accuracy and precision −5.8%~11.7% and 3.7%~11.6%, respectively. The other validation parameters, recovery and matrix effect, ranged from 96.6% to 99.4% and 95.3% to 101.4%, respectively. Propofol standard was quantified to evaluate possible loss due to the concentration processes, nitrogen gas and centrifugal vacuum. These two concentration processes resulted in notable decrease in the quantity of propofol, signifying avoiding any concentration processes during propofol quantification. Also, to confirm suitability of the developed method, authentic human plasma samples were analyzed. The selective assay method using MCX cartridge and GC-MS facilitated quantification of propofol in plasma sample accurately by preventing any losses due to the concentration processes.

  19. Selective and Accurate Determination Method of Propofol in Human Plasma by Mixed-Mode Cation Exchange Cartridge and GC-MS.

    Science.gov (United States)

    Pyo, Jae Sung

    2016-01-01

    A gas chromatography-mass spectrometry (GC-MS) method for the determination of propofol in human plasma has been developed and validated. Propofol was extracted from human plasma by using mixed-mode cation exchange/reversed-phase (MCX) cartridges. As propofol easily volatilizes during concentration, 100% methanol was injected directly into GC-MS to elute propofol. Despite avoiding concentration process of the eluted solution, lower limit of quantization (LLOQ) of propofol was 25 ng/mL. The validated method exhibited good linearity (R (2) = 0.9989) with accuracy and precision -5.8%~11.7% and 3.7%~11.6%, respectively. The other validation parameters, recovery and matrix effect, ranged from 96.6% to 99.4% and 95.3% to 101.4%, respectively. Propofol standard was quantified to evaluate possible loss due to the concentration processes, nitrogen gas and centrifugal vacuum. These two concentration processes resulted in notable decrease in the quantity of propofol, signifying avoiding any concentration processes during propofol quantification. Also, to confirm suitability of the developed method, authentic human plasma samples were analyzed. The selective assay method using MCX cartridge and GC-MS facilitated quantification of propofol in plasma sample accurately by preventing any losses due to the concentration processes.

  20. Comparison of the Usefulness of SPE Cartridges for the Determination of β-Blockers and β-Agonists (Basic Drugs in Environmental Aqueous Samples

    Directory of Open Access Journals (Sweden)

    Magda Caban

    2015-01-01

    Full Text Available Even though the methodology used for the determination of β-blockers and β-agonists in environmental samples is based mainly on solid-phase extraction (SPE and gas chromatography or liquid chromatography with mass spectrometric detection, the available literature data on the applied SPE procedures is rather sparse. In this paper such comparison is presented. Moreover, the usefulness of the eight SPE cartridges for the determination of five β-blockers (acebutolol, atenolol, metoprolol, nadolol, and propranolol and two β-agonists (salbutamol and terbutaline in environmental aqueous samples using GC techniques is tested. Among them, three (the trifunction sorbent Strata Screen C, the copolymers LiChrolut EN, and the functionalized copolymer Isolute ENV+ were used for the first time for this purpose. It was confirmed that polystyrene-divinylbenzene-N-vinylpyrrolidone copolymers (PS-DVB-VP, Strata-X, and Oasis HLB cartridges have a better potential than a cation-exchange sorbent for the extraction of the target drugs from environmental water samples. However, it should be stressed out that the direct application of the tested SPE conditions for the analysis of real environmental water samples is not possible, and such parameters, like volume of loading sample, appropriate solvents for washing and elution steps, and so forth, must be optimized again in order to achieve satisfactory recovery values for the target compounds.

  1. Determination of volatile organic compounds including alcohols in refill fluids and cartridges of electronic cigarettes by headspace solid-phase micro extraction and gas chromatography-mass spectrometry.

    Science.gov (United States)

    Lim, Hyun-Hee; Shin, Ho-Sang

    2017-02-01

    An analytical method for the detection of 14 volatile organic compounds (VOCs) was developed to investigate VOCs in refill fluids and cartridges of electronic cigarettes (EC) using headspace solid-phase micro extraction (HS-SPME) coupled with gas chromatography-mass spectrometry (GC-MS). In total, 14 VOCs were identified and quantified in 283 flavored liquids, 21 nicotine liquids, and 12 disposable cartridges. The detected concentration ranges of the VOCs are as follows: benzene (0.008-2.28 mg L(-1)), toluene (0.006-0.687 mg L(-1)), ethylbenzene (0.01-1.21 mg L(-1)), m-xylene (0.002-1.13 mg L(-1)), p-xylene (0.007-2.8 mg L(-1)), o-xylene (0.004-2.27 mg L(-1)), styrene (0.011-0.339 mg L(-1)), ethyl acetate (0.3-669.9 mg L(-1)), ethanol (16-38,742 mg L(-1)), methanol (66-3375 mg L(-1)), pyridine (0.077-99.7 mg L(-1)), acetylpyrazine (0.077-147 mg L(-1)), 2,3,5-trimethylpyrazine (0.008-96.8 mg L(-1)), and octamethylcyclotetrasiloxane (0.1-57.2 mg L(-1)). Benzene, toluene, ethylbenzene, m-xylene, p-xylene, and o-xylene coexisted in samples, which may have originated from the use of petrogenic hydrocarbons as an extraction solvent for flavor and nicotine from natural plants. The maximum detected concentrations of benzene, methanol, and ethanol in liquid samples were found in quantities higher than their authorized maximum limits as residual solvents in pharmaceutical products.

  2. Use of chloroflurocarbons as internal standards for the measurement of atmospheric non-methane volatile organic compounds sampled onto solid adsorbent cartridges.

    Science.gov (United States)

    Karbiwnyk, Christine M; Mills, Craig S; Helmig, Detlev; Birks, John W

    2003-03-01

    Solid adsorbents have proven useful for determining the vertical profiles of volatile organic compounds (VOCs) using sampling platforms such as balloons, kites, and light aircraft, and those profiles provide valuable information about the sources, sinks, transformations, and transport of atmospheric VOCs. One of the largest contributions to error in VOC concentrations is the estimation of the volume of air sampled on the adsorbent cartridge. These errors arise from different sources, such as variations in pumping flow rates from changes in ambient temperature and pressure with altitude, and decrease in the sampling pump battery power. Another significant source for sampling rate variations are differences in the flow resistance of individual sampling cartridges. To improve the accuracy and precision of VOC measurements, the use of ambient chlorofluorocarbons (CFCs) as internal standards was investigated. A multibed solid adsorbent, AirToxic (Supelco), was chosen for its wide sampling range (C3-C12). Analysis was accomplished by thermal desorption and dual detection GC/FID/ECD, resulting in sensitive and selective detection of both VOCs and CFCs in the same sample. Long-lived chlorinated compounds (CFC-11, CFC-12, CFC-113, CCl4 and CH3CCl3) banned by the Montreal Protocol and subsequent amendments were studied for their ability to predict sample volumes using both ground-based and vertical profiling platforms through the boundary layer and free troposphere. Of these compounds, CFC-113 and CCl4 were found to yield the greatest accuracy and precision for sampling volume determination. Use of ambient CFC-113 and CCl4 as internal standards resulted in accuracy and precision of generally better than 10% for the prediction of sample volumes in ground-, balloon-, and aircraft-based measurements. Consequently, use of CFCs as reference compounds can yield a significant improvement of accuracy and precision for ambient VOC measurements in situations where accurate flow

  3. OZONE REACTION WITH N-ALDEHYDES (N=4-10), BENZALDEHYDE, ETHANOL, ISOPROPANOL, AND N-PROPANOL ADSORBED ON A DUAL-BED GRAPHITIZED CARBON/CARBON MOLECULAR SIEVE ADSORBENT CARTRIDGE

    Science.gov (United States)

    Ozone reacts with n-aldehydes (n = 4 - 10), benzaldehyde, ethanol, isopropanol, and n-propanol adsorbed on a dual-bed graphitized carbon/carbon molecular sieve adsorbent cartridge. Destruction of n-aldehydes increases with n number and with ozone concentration. In some samp...

  4. Efficiency of a miniaturized silica monolithic cartridge in reducing matrix ions as demonstrated in the simultaneous extraction of morphine and codeine from urine samples for quantification with liquid chromatography-tandem mass spectrometry (LC-MS/MS).

    Science.gov (United States)

    Nema, T; Chan, E C Y; Ho, P C

    2011-09-01

    Presence of matrix ions could negatively affect the sensitivity and selectivity of liquid chromatography-tandem mass spectrometer (LC-MS/MS). In this study, the efficiency of a miniaturized silica monolithic cartridge in reducing matrix ions was demonstrated in the simultaneous extraction of morphine and codeine from urine samples for quantification with LC-MS. The miniaturized silica monolith with hydroxyl groups present on the largely exposed surface area function as a weak cation exchanger for solid phase extraction (SPE). The miniaturized silica cartridge in 1 cm diameter and 0.5 cm length was housed in a 2-ml syringe fixed over a SPE vacuum manifold for extraction. The cleaning effectiveness of the cartridge was confirmed by osmometer, atomic absorption spectrometer, LC-MS and GC-TOFMS. The drugs were efficiently extracted from urine samples with recoveries ranging from 86% to 114%. The extracted analytes, after concentration and reconstitution, were quantified using LC-MS/MS. The limits of detection for morphine and codeine were 2 ng/ml and 1 ng/mL, respectively. The relative standard deviations of measurements ranged from 3% to 12%. The monolithic sorbent offered good linearity with correlation coefficients > 0.99, over a concentration range of 50-500 ng/ml. The silica monolithic cartridge was found to be more robust than the particle-based packed sorbent and also the commercial cartridge with regards to its recyclability and repeated usage with minimal loss in efficiency. Our study demonstrated the efficiency of the miniaturized silica monolith for removal of matrix ions and extraction of drugs of abuse in urinary screening.

  5. 褶型筒式过滤器阻力性能研究%Research on Pressure Drop Performance of Pleated Cartridge Filters

    Institute of Scientific and Technical Information of China (English)

    何维浪; 林忠平; 张晓磊; 陆涛; 陈伟忠

    2012-01-01

    Compared With conventional bag filters, pleated cartridge filter with a high density of V-shaped pleated structure has a larger filter area, leading to a smaller filtration velocity. As a result, the pressure drop of this kind filter is reduced. However, when the amount of pleats increases, the distance between two pleats will become smaller, which will make the flow turbulent. As a result, the frictional resistance will increase, and the effective filter area will be lowered, which will lead to the rise of pressure drop of filter paper. What's more, when the dust loading on the filter becomes greater, the pleat channel becomes more clogged, and the air becomes more turbulent, and as a result, the filter area becomes less and the pressure drop becomes bigger. The dust holding capacity per unit area of tilter paper is far more than the Cartridge Filter per unit area.%与传统的袋式过滤器相比,筒式过滤器采用高密度的V型褶结构,增加了过滤面积,降低滤纸的过滤风速,从而有效地减小了滤纸阻力,从某种程度上降低了筒式过滤器的阻力。但是通过理论分析和试验研究发现筒式过滤器的滤纸褶密度增大,也必然导致滤纸褶间距减小,因而会使得气流在褶通道内部发生紊乱现象,造成气流分布不均匀,这样不仅增大了滤纸褶通道内部的摩擦阻力,还减小了筒式过滤器的有效过滤面积。同时试验研究还发现,随着过滤器容尘量增加,部分过滤通道发生堵塞现象,气流更加紊乱,有效过滤面积进一步减小,由此造成的结果是筒式过滤器单位面积容尘量远远低于滤纸的单位面积容尘量。

  6. Quantitative method of viral pollution determination for large volume of water using ferric hydroxide gel impregnated on the surface of glassfibre cartridge

    Directory of Open Access Journals (Sweden)

    Akira Homma

    1974-01-01

    Full Text Available Quantitative method of viral pollution determination for large volume of water using ferric hydroxide gel impregnated on the surface of glassfibre cartridge filter. The use of ferric hydroxide gel, impregnated on the surface of glassfibre cartridge filter enable us to recover 62.5% of virus (Poliomylitis type I, Lsc strain exsogeneously added to 400 liters of tap-water. The virus concentrator system consists of four cartridge filters, in which the three first one are clarifiers, where the contaminants are removed physically, without significant virus loss at this stage. The last cartridge filter is impregnated with ferric hydroxide gel, where the virus is adsorbed. After the required volume of water has been processed, the last filter is removed from the system and the viruses are recovered from the gel, using 1 liter of glycine/NaOH buffer, at pH 11. Immediately the eluate is clarified through series of cellulose acetate membranes mounted in a 142mm Millipore filter. For the second step of virus concentration, HC1 1N is added slowly to the eluate to achieve pH 3.5-4. MgC1, is added to give a final concentration of 0.05M and the viruses are readsorbed on a 0.45 , porosity (HA cellulose acetate membrane, mounted in a 90 mm Millipore filter. The viruses are recovered using the same eluent plus 10% of fetal calf serum, to a final volume of 3 ml. In this way, it was possible to concentrate virus from 400 liters of tap-water, into 1 liter in the first stage of virus concentration and just to 3 ml of final volume in a second step. The efficiency, simplicity and low operational cost, provded by the method, make it feasible to study viral pollution of recreational and tap-water sources.Relata-se o emprego de um concentrador portátil, o qual se mostrou capaz de recuperar 62,5% dos vírus (Polio I, amostra Lsc experimentalmente dispersos em 400 litros de água, os quais foram reduzidos a 3 ml. O sistema concentrador de vírus é composto de quatro

  7. Comparison of Different Cartridges of Solid Phase Extraction for Determination of Polyphenols in Tobacco by UPLC/MS/MS and Multivariate Analysis

    Institute of Scientific and Technical Information of China (English)

    ZHANG Xia; LIU Wei; XU Yong; YANG Liu; KONG Wei-song; RUI Xiao-dong; YANG Shuai; CHEN Yong-kuan; MIAO Ming-ming

    2011-01-01

    The comparison of solid phase extraction(SPE) for the preconcentration and isolation of polyphenols in tobacco samples was carried out by ultra-high performance liquid chromatography/tandem mass spectrometry (UPLC/MS/MS) and multivariate analysis.Several adsorbing materials of SPE(C18,NH2,SAX and OASIS) were investigated.It was found that the C18 and OASIS cartridges can not only speed up the purification process,but also simplify the SPE operation.A UPLC/MS/MS was used for the determination of polyphenols in tobacco samples after purification.All analytes were separated and determined in 2 min.The limit of detection was 0.05 ng/mL.Cluster analysis(CA) and principal component analysis(PCA) were used for the analysis of 4 varieties(flue-cured tobacco,oriental tobacco,sun-cured tobacco and burley) in order to interpret the effect of planting and machining process on the concentration of polyphenols.The different types of tobacco samples could be easily clustered by CA.PCA on the chemical composition of tobacco resulted in two principal components(PCs) that take 84.2% of the total variance.The PCA and CA indicate that the polyphenols can be used for distinguishing tobacco types.

  8. Penetrating chest trauma caused by a blank cartridge actuated rubber ball projectile: case presentation and ballistic investigation of an uncommon weapon type.

    Science.gov (United States)

    Frank, Matthias; Peters, Dieter; Klemm, Wolfram; Grossjohann, Rico; Ekkernkamp, Axel; Bockholdt, Britta; Seifert, Julia

    2017-05-23

    Recently, an increasing number of an uncommon weapon type based on a caliber 6-mm Flobert blank cartridge actuated revolver which discharges 10-mm-diameter rubber ball projectiles has been confiscated by police authorities following criminal offenses. A recent trauma case presenting with a penetrating chest injury occasioned an investigation into the basic ballistic parameters of this type of weapon. Kinetic energy E of the test projectiles was calculated between 5.8 and 12.5 J. Energy density ED of the test projectiles was close to or higher than the threshold energy density of human skin. It can be concluded that penetrating skin injuries due to free-flying rubber ball projectiles discharged at close range cannot be ruled out. However, in case of a contact shot, the main injury potential of this weapon type must be attributed to the high energy density of the muzzle gas jet which may, similar to well-known gas or alarm weapons, cause life-threatening or even lethal injuries.

  9. Light-emitting diode induced fluorescence (LED-IF) detection design for a pen-shaped cartridge based single capillary electrophoresis system.

    Science.gov (United States)

    Kerékgyártó, Márta; Kerekes, Tamás; Tsai, Eric; Amirkhanian, Varoujan D; Guttman, András

    2012-09-01

    CGE is a well-established separation technique for the analysis of biologically important molecules such as nucleic acids. The inherent high resolving power, rapid analysis times, excellent detection sensitivity, and quantification capabilities makes this method favorable compared to conventional manual polyacrylamide and agarose slab gel electrophoresis techniques. In this paper we introduce a novel single-channel capillary gel electrophoresis system with LED-induced fluorescence detection also utilizing a compact pen-shaped capillary cartridge design for automatic analysis of samples from a 96-well plate. To evaluate the suitability of the system, 1000 genomic DNA(gDNA) samples were analyzed in gel filled capillaries and detected by the microball ended excitation and emission optical fiber based LED-induced fluorescence detection system. Excellent migration time reproducibility of RSD <0.75% was obtained over the course of 1000 runs. The system rapidly distinguished between intact and degraded gDNA samples, therefore provided important information if they could be used for downstream quantitative PCR processing where high-quality intact gDNA was key. We envision that this novel system design will rapidly find new applications in both research and clinical diagnostic laboratories as a highly sensitive and easy to use bio-analytical approach.

  10. Molecularly imprinted polymer cartridges coupled on-line with high performance liquid chromatography for simple and rapid analysis of human insulin in plasma and pharmaceutical formulations.

    Science.gov (United States)

    Moein, Mohammad Mahdi; Javanbakht, Mehran; Akbari-adergani, Behrouz

    2014-04-01

    In this paper, a novel method is described for automated determination of human insulin in biological fluids using principle of sequential injection on a molecularly imprinted solid-phase extraction (MISPE) cartridge as a sample clean-up technique combined with high performance liquid chromatography (HPLC). The water-compatible molecularly imprinted polymers (MIPs) were prepared using methacrylic acid as a functional monomer, ethylene glycol dimethacrylate as a cross-linker, chloroform as a porogen and insulin as a template molecule. The imprinted polymers were then employed as the solid-phase extraction sorbent for on-line extraction of insulin from human plasma samples. To achieve the best condition, influential parameters on the extraction efficiency were thoroughly investigated. Rapid and simple analysis of the hormone was successfully accomplished through the good selectivity of the prepared sorbent coupled with HPLC. Limits of detection (LOD) and quantification (LOQ) of 0.2 ng mL(-1), 0.7 ng mL(-1), and 0.03 ng mL(-1), 0.1 ng mL(-1) were obtained in plasma and urine respectively. The obtained data exhibited the great recoveries for extraction of insulin from human plasma and pharmaceutical samples, higher than 87%.

  11. On-cartridge derivatisation using a calixarene solid-phase extraction sorbent for facile, sensitive and fast determination of formaldehyde in beer.

    Science.gov (United States)

    Deng, Zhifen; Hu, Kai; Zhang, Yongming; Zhao, Wenjie; Wang, Fei; Guo, Ling; Zhang, Wenfen; He, Juan; Huang, Yanjie; Zhang, Shusheng

    2016-11-15

    This work demonstrates the successful application of an on-cartridge derivatisation procedure for facile, fast and sensitive determination of formaldehyde in beer by HPLC-UV. The derivatisation and solid-phase extraction (SPE) were integrated into a novel calixarene SPE sorbent: tetraazacalix[2]arene[2]triazine bonded silica gel. Specifically, 2,4-dinitrophenylhydrazine was adsorbed onto the sorbent in advance, based on the charge-transfer interaction between the macrocyclic molecule and nitrobenzenes. The method was optimised and validated: under the optimal conditions of derivatisation, SPE and HPLC separation, good linearity was obtained in the range of 0.080-3.2μgmL(-1) with a correlation coefficient of 0.9939, the limit of detection was 3.0ngmL(-1) (S/N=3), the limit of quantification was 10ngmL(-1) (S/N=10), and the recovery level using this method was desirable at 75-84%. The developed method was successfully applied to determine formaldehyde content in real beer samples; the results were in the range of 0.11-1.1μgmL(-1).

  12. Solid-phase extraction of phosphorous-containing amino acid herbicides from biological specimens with a zirconia-coated silica cartridge.

    Science.gov (United States)

    Watanabe, Daisuke; Ohta, Hikoto; Yamamuro, Tadashi

    2014-10-15

    We report a rapid solid-phase extraction method for glyphosate (Glyp), glufosinate (Gluf), and bialaphos (Bial) using a zirconia-coated silica cartridge, which interacts specifically with phosphorous-containing amino acid herbicides (PAAHs). We extracted PAAHs from serum and urine samples. The PAAHs were derivatized with trimethyl orthoacetate-acetic acid and analyzed by ultra-performance liquid chromatography/tandem mass spectrometry (UPLC-MS/MS). The intra-day and inter-day accuracy was within ±13% RE, the intra-day and inter-day precision was less than 12% RSD, and the total recovery was more than 60% for Glyp and more than 80% for Gluf and Bial. The linearity ranges of the calibration curves of the serum samples were 0.2-10,000μg/mL for Glyp, 0.1-1000μg/L for Gluf, and 0.5-1000μg/L for Bial; and those of the urine samples were 0.4-20,000μg/L for Glyp, 0.2-2000μg/L for Gluf, and 0.1-2000μg/L for Bial. This range covers almost all the reported poisoning cases involving these compounds, from very mild to fatal cases. The present paper offers a universal cleanup method for PAAHs in serum and urine samples for clinical and forensic analysis.

  13. Determination of nicotine, tar, volatile organic compounds and carbonyls in mainstream cigarette smoke using a glass filter and a sorbent cartridge followed by the two-phase/one-pot elution method with carbon disulfide and methanol.

    Science.gov (United States)

    Uchiyama, Shigehisa; Hayashida, Hideki; Izu, Rina; Inaba, Yohei; Nakagome, Hideki; Kunugita, Naoki

    2015-12-24

    We have developed a new analytical method for the determination of nicotine, tar, volatile organic compounds and carbonyls in main-stream cigarette smoke using a sorbent cartridge packed with Carboxen 572 (CX-572) and a Cambridge filter pad (CFP) followed by the two-phase/one-pot elution method. A CX-572 cartridge is installed between the intake of the CFP and the pump of the smoking machine. Gaseous compounds collected with the CX-572 cartridge and total particulate matter (TPM) collected with the CFP are coeluted simultaneously in the same vial and then analyzed by high-performance liquid chromatography (HPLC), gas chromatography-mass spectrometry (GC/MS) and gas chromatograph-thermal conductivity detector (GC/TCD). Carbonyl compounds are determined by adding derivatizing reagent (2,4-dinitrophenylhydrazine, DNPH) to the eluate followed by HPLC analysis. VOCs and nicotine are determined by GC/MS, and water is determined by GC/TCD. The same sample eluate solution is used for HPLC, GC/MS and GC/TCD analyses. As a result of measuring main-stream cigarette smoke generated from reference cigarettes, almost all carbonyl compounds and VOCs except formaldehyde were passed through a CFP and trapped in a CX-572 cartridge. 100% of nicotine, tar and TPM were trapped in a CFP. 50% of water and 53% of formaldehyde were trapped in a CFP. The one-pot data is almost equal to the sums of CFP (particulate matter) and CX-572 (gaseous compounds) data. The two-phase/one-pot elution method can simultaneously measure nicotine, tar, volatile organic compounds and carbonyl compounds in cigarette smoke with simple operation and small amounts of reagents. Copyright © 2015 Elsevier B.V. All rights reserved.

  14. 天然气净化用过滤元件性能测定与分析%Performance Test of Filter Cartridge for Natural Gas Purification

    Institute of Scientific and Technical Information of China (English)

    肖连; 古自强; 常程; 邵春明; 姬忠礼

    2015-01-01

    In the long-distance transmission process of natural gas, the reliable operation of the compressor u-nits and pipelines is seriously affected by dusts and droplets entrained in natural gas. The performance of dry seal gas filter cartridges used in centrifugal compressors is investigated. The results show that gas-liquid filtration per-formance, gas-solid filtration performance, impact resistance performance and collapse performance can be effec-tively evaluated by the established measurement methods. Significant difference in the evolution of pressure drop can be observed in different filtration process. Pressure drop increases until it remains constant at the steady stage in the gas-liquid filtration process. However, pressure drop remains increasing through the gas-solid filtration process. There is no corresponding relation between gas-liquid filtration efficiency and gas-solid filtration efficien-cy. When droplets are entrained in natural gas at practical condition, gas-liquid filtration efficiency is preferable for being the evaluation index of filtration performance. When the fluctuation of pressure is less than 0. 5 MPa, the per-formance of the filter cartridges will not be affected by short period airflow impact.%在天然气长距离管道输送过程中, 天然气夹带的固态及液态杂质严重影响压缩机组及管道的可靠运行. 为此, 利用天然气净化用过滤元件性能检测装置对离心压缩机干气密封过滤器滤芯的性能进行了检测. 检测结果表明, 所建立的检测方法可有效评价过滤元件的气液过滤性能、气固过滤性能、 耐冲击性能和压溃特性; 滤芯压降变化情况在不同过滤过程中存在明显差别, 气液过滤中滤芯压降逐渐升高, 最终在稳态阶段保持稳定, 而在气固过滤中, 滤芯压降始终呈增长趋势; 滤芯气液过滤效率与气固过滤效率之间无对应关系, 现场工况下, 天然气内含有液态杂质时, 宜选用气液过

  15. Community Laboratory Testing for Cryptosporidium: Multicenter Study Retesting Public Health Surveillance Stool Samples Positive for Cryptosporidium by Rapid Cartridge Assay with Direct Fluorescent Antibody Testing

    Science.gov (United States)

    Roellig, Dawn M.; Yoder, Jonathan S.; Madison-Antenucci, Susan; Robinson, Trisha J.; Van, Tam T.; Collier, Sarah A.; Boxrud, Dave; Monson, Timothy; Bates, Leigh Ann; Blackstock, Anna J.; Shea, Shari; Larson, Kirsten; Xiao, Lihua; Beach, Michael

    2017-01-01

    Cryptosporidium is a common cause of sporadic diarrheal disease and outbreaks in the United States. Increasingly, immunochromatography-based rapid cartridge assays (RCAs) are providing community laboratories with a quick cryptosporidiosis diagnostic method. In the current study, the Centers for Disease Control and Prevention (CDC), the Association of Public Health Laboratories (APHL), and four state health departments evaluated RCA-positive samples obtained during routine Cryptosporidium testing. All samples underwent “head to head” re-testing using both RCA and direct fluorescence assay (DFA). Community level results from three sites indicated that 54.4% (166/305) of Meridian ImmunoCard STAT! positives and 87.0% (67/77) of Remel Xpect positives were confirmed by DFA. When samples were retested by RCA at state laboratories and compared with DFA, 83.3% (155/186) of Meridian ImmunoCard STAT! positives and 95.2% (60/63) of Remel Xpect positives were confirmed. The percentage of confirmed community results varied by site: Minnesota, 39.0%; New York, 63.9%; and Wisconsin, 72.1%. The percentage of confirmed community results decreased with patient age; 12.5% of community positive tests could be confirmed by DFA for patients 60 years of age or older. The percentage of confirmed results did not differ significantly by sex, storage temperature, time between sample collection and testing, or season. Findings from this study demonstrate a lower confirmation rate of community RCA positives when compared to RCA positives identified at state laboratories. Elucidating the causes of decreased test performance in order to improve overall community laboratory performance of these tests is critical for understanding the epidemiology of cryptosporidiosis in the United States (US). PMID:28085927

  16. A Method for Multiple Mycotoxin Analysis in Wines by Solid Phase Extraction and Multifunctional Cartridge Purification, and Ultra-High-Performance Liquid Chromatography Coupled to Tandem Mass Spectrometry

    Directory of Open Access Journals (Sweden)

    Naoki Mochizuki

    2012-06-01

    Full Text Available An analytical method using two solid phase extractions and ultra-high-performance liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS was developed for the identification and quantification of 14 mycotoxins (patulin, deoxynivalenol, aflatoxins B1, B2, G1, G2, M1, T-2 toxin, HT-2 toxin, zearalenone, fumonisins B1, B2, B3, and ochratoxin A in domestic and imported wines. Mycotoxins were purified with an Oasis HLB cartridge, followed by a MultiSepTM #229 Ochra. As a result, sufficient removal of the pigments and highly polar matrices from the red wines was achieved. UHPLC conditions were optimized, and 14 mycotoxins were separated in a total of 13 min. Determinations performed using this method produced high correlation coefficients for the 14 mycotoxins (R > 0.990 and recovery rates ranging from 76 to 105% with good repeatability (relative standard deviation RSD < 12%. Twenty-seven samples of domestic and imported wines were analyzed using this method. Although ochratoxin A (OTA and fumonisins (FMs were detected in several samples, the FM levels were less than limits of quantification (LOQs (1 μg/L, and even the largest of the OTA levels was below the EU regulatory level (2 μg/L. These results suggest that the health risk posed to consumers from the wines available in Japan is relatively low.

  17. Laser Cartridge Concept Development Study

    Science.gov (United States)

    1976-04-01

    Infrared Lasers", IEEE J. Quantum Elect., QE-8 (9) 759 (1972). 2. Internal Correspondence, R. Pike to G. Golden, " Synthesis of Bis-(U...dimethylaminodithiobenzil)-nickel, Dec. I1*, 1972. 3. G. N. Schrauzer and V. P. Mazweg, "Preparation, Reactions, and Structure of Bisdithio-a diketone Complexes of

  18. Defect Detection and One-Dimensional Size Measurement of Toner Cartridge Based on Halcon%基于Halcon的硒鼓缺陷检测与一维尺寸测量

    Institute of Scientific and Technical Information of China (English)

    朱先锋; 潘洪军

    2014-01-01

    Surface defect detection and size measurement of the toner cartridge is an important part to determine whether it is qualified. To achieve this aspect of work automation, the toner cartridge surface point defects and line defects are accurately detected and classified by mathematical morphology operators of image processing algorithms, and its size is precisely measured according to sub-pixel measurements. The cartridge automatic defect detection and size measurement system is developed by the special machine vision software Halcon and . NET. Testing shows that the system has a high accuracy, speed, stability and other distinctive characteristics.%为实现硒鼓表面缺陷检测和尺寸测量的自动化,运用图像处理算法中的数学形态学算子对硒鼓表面点缺陷和线缺陷进行精确检测与分类,并根据亚像素测量方法对硒鼓尺寸进行精确测量,通过机器视觉专用软件Halcon和。 NET开发了硒鼓缺陷自动检测与尺寸测量系统。测试结果表明,该方法与应用像素级测量法相比,其精度提高1~2个像素,具有精度高、稳定性强等优点。

  19. A Fully Automated Radiosynthesis of [18F]Fluoroethyl-Diprenorphine on a Single Module by Use of SPE Cartridges for Preparation of High Quality 2-[18F]Fluoroethyl Tosylate

    Directory of Open Access Journals (Sweden)

    Gjermund Henriksen

    2013-06-01

    Full Text Available We have developed a new method for automated production of 2-[18F]fluoroethyl tosylate ([18F]FETos that enables 18F-alkylation to provide PET tracers with high chemical purity. The method is based on the removal of excess ethylene glycol bistosylate precursor by precipitation and subsequent filtration and purification of the filtrate by means of solid phase extraction cartridges (SPE. The method is integrated to a single synthesis module and thereby provides the advantage over previous methods of not requiring HPLC purification, as demonstrated by the full radiosynthesis of the potent opioid receptor PET tracer [18F]fluoroethyldiprenorphine.

  20. 覆膜滤简侧壁压力正峰值的测试与分析%Pressure Peak Test and Analysis of Membrane Cartridge Filter Side Wall

    Institute of Scientific and Technical Information of China (English)

    郑娟; 张明星; 周奇杰; 张一帜; 蔡广贝

    2011-01-01

    In order to research the effects of peak size of side wall at the time of pulse jet on cleaning performance of normal polyester cartridge. The polytetrafluoroethene (PTFE) microporous membrane filter tube and self-made pulse injection experiment platform was used to tested the pressure peak size of cartridge filter side wall. Two kinds filter tubes with 47 mm in diameter and 1 000, 1 500 mm in length were tested and analyzed, and compared to the pressure peak size of ordinary polyester fiber filter tube. The results showed that the upper, middle and lower pressure peak sizes of PTFE microporous membrane filter tube were 5~10 times as that of ordinary polyester fiber filter tube. The main filtering mechanism was cartridge cleaning effect of PTFE microporous membrane filter tube whose filtration and ventilation were small was better than ordinary polyester fiber tube. Comparing two kinds of membrane filter tube with 1 000, 1 500 mm in length in the same condition, it was found that the trends of pressure values changes were different in the cartridge length direction.%为研究脉冲喷吹时滤筒侧壁压力正峰值大小对普通聚酯滤筒的清灰性能的影响,针对材质为聚四氟乙烯的覆膜滤筒,采用自制脉冲喷吹实验台,通过测试滤筒侧壁压力正峰值大小,对直径为147 mm、长度为1 000、1 500 mm的两种滤筒进行测试与分析,并与普通聚酯纤维滤筒的侧壁压力正峰值大小相比较.结果表明:聚四氟乙烯覆膜滤筒各测点的压力正峰值约是普通聚酯纤维滤筒的5~10倍,过滤机理主要为表现过滤,且透气性小的聚四氟乙烯覆膜滤筒清灰效果比普通聚酯纤维滤筒要好;在相同务件下,不同长度的滤筒在滤筒长度方向上,其压力值变化趋势不同.

  1. 基于Nelder-Mead算法的插装阀AMESim仿真模型优化设计%Optimization Design of Cartridge Valve's AMESim Model Based on Nelder-Mead Simplex Method

    Institute of Scientific and Technical Information of China (English)

    马昌训; 吴运新; 唐宏宾; 高明

    2011-01-01

    详细分析二通插装阀的数学模型,建立其流量与进出口压差之间的关系,利用AMESim中的Hydraulic Component Design(HCD)库搭建二通插装阀的仿真模型.根据无导数的Nelder-Mead单纯形优化算法理论,借助Matlab对模型的结构参数进行优化.采用优化结果仿真得到的流量-压降特性曲线与期望特性曲线相当接近,验证了仿真模型的准确性和优化方法的有效性.%Based on mathematical model of cartridge valve, the relationship of flow rate and differences between import and export was established.The simulation model of cartridge valve was built using hydraulic component design (HCD) library in AMESim.The structural parameters were optimized by Matlab according to the no-derivative theory of Nelder-Mead simplex method.By comparing the optimized characteristic curve of flow rate-pressure drop with expectation, the result show that the model is accurate and the optimization is valid.

  2. Time Since Discharge of China-made Type 64 and Type 92 Pistol Cartridges%64式与92式手枪弹的射击时间

    Institute of Scientific and Technical Information of China (English)

    鲍立垠; 周志飞; 王晓琳; 李轶昳; 张刚; 马新和

    2015-01-01

    Estimation of cartridge discharge time is very important for the investigation of same gun-firing related cases. Accompanied with shooting, nitrate gunpowder in cartridges burns and reacts vigorously, while a large series of gaseous and solid reaction compounds are generated and absorbed onto the internal surface of cartridge cases. Experiments were conducted in order to detect the volatile nitrate organic gunshot residues (OGRS) of China-made 7.62 mm type 64 and 9 mm type 92 pistol cartridge cases. After discharged, these two cartridge cases were sampled using solid phase micro-extraction (SPME), and analyzed by gas chromatographic-thermal energy analyzer (GC-TEA).One double peak can be observed in all GC-TEA chromatogram as late as 10 days past discharge. The double peak became weaker along with the time elapsing since discharge. From the discharge time of Day 1 to Day 7, a notable peak was identified in GC-TEA chromatogram of the two cartridge cases in the test time segment from 1 to 2 min. On Day 1, it was merged by one sub-peak of weaker and sharper plus another sub-one of stronger and broader, continuing to be only a peak notably wider, becoming much weaker on Day 9, and eventually hardly seen on Day 11 after discharge. For the first time, the variety curves of the volatile nitrate organic compound content of China-made 7.62 mm type 64 and 9 mm type 92 pistol cartridge cases were developed, and the time since discharge of these two cartridge cases can be estimated.%现代枪弹的发射常伴随着含氮发射药燃烧产生多种气相和固相射击残留物的过程,射击后可挥发的射击残留物附着于弹壳表面,并随时间不断从弹壳内表面逸散。这种逸散过程的量度是估计发射时间的重--素。采用固相微萃取方法对国产64式7.62 mm 手枪弹和92式9 mm 手枪弹进行分析提取,使用气相色谱-热能分析仪分析提取的挥发性含氮有机物。测量含氮有机物相对含量随时间的推

  3. Analysis of polynuclear aromatic hydrocarbons in olive oil after solid-phase extraction using a dual-layer sorbent cartridge followed by high-performance liquid chromatography with fluorescence detection.

    Science.gov (United States)

    Stenerson, Katherine K; Shimelis, Olga; Halpenny, Michael R; Espenschied, Ken; Ye, Maochun M

    2015-05-27

    A simple and easy direct solid-phase extraction (SPE) method was developed for the analysis of polynuclear aromatic hydrocarbons (PAHs) in olive oil using a dual-layer cartridge containing activated Florisil and a mixture of octadecyl (C18)-bonded and zirconia-coated silicas. Undiluted olive oil was applied directly to the SPE cartridge, and the sample was eluted with acetonitrile solvent. Background in the extract was found to be low enough for either gas chromatography-mass spectrometry (GC-MS) or high-performance liquid chromatography with fluorescence detection (HPLC-FLD) analysis. Average recoveries for 16 different PAHs from spiked olive oil replicates were >75%, with intraday precisions of <20% relative standard deviation (% RSD). Detection limits ranged from 0.2 to 1.0 μg/kg and, specifically for the PAHs listed in EC Regulation 835/2011, benzo(a)anthracene, chrysene, benzo(b)fluoranthene, and benzo(a)pyrene, were from 0.3 to 0.7 μg/kg. The method was then applied to determine the PAH content present in commercial samples of refined versus extra-virgin olive oils.

  4. Nanotechnology for forensic sciences: analysis of PDMS replica of the case head of spent cartridges by optical microscopy, SEM and AFM for the ballistic identification of individual characteristic features of firearms.

    Science.gov (United States)

    Valle, Francesco; Bianchi, Michele; Tortorella, Silvia; Pierini, Giovanni; Biscarini, Fabio; D'Elia, Marcello

    2012-10-10

    A novel application of replica molding to a forensic problem, viz. the accurate reproduction of the case head of gun and rifle cartridges, prior and after been shot, is presented. The fabrication of an arbitrary number of identical copies of the region hit by the firing pin and by the breech face is described. The replicas can be (i) handled without damaging the original evidence, (ii) distributed to different law enforcement agencies for comparison against other evidences found on crime scenes or ballistic tests of seized firearms, (iii) maintained on a file by the laboratories. A detailed analysis of the morphological features of the replicas has been carried out by standard microscopy techniques as well as by advanced microscopy such as scanning probe and scanning electron leading to a quantitative morphological characterization of the case heads down to the nanometer scale. The assignment of the cartridge replicas to the shooting weapon is demonstrated to hold below the micron scale, while it is hindered at the nanometer level both by the manufacturing differences and by eventual modifications occurring on the firing pin.

  5. Experimental study on ultra-fine powder purification of pulse-jet cartridge dust collector%脉冲滤筒除尘器对超细粉体净化的实验研究

    Institute of Scientific and Technical Information of China (English)

    林莉君; 周露

    2012-01-01

    随着工业的快速发展,空气中颗粒污染物的含量和种类越来越多,不仅对人体健康造成危害,颗粒污染还对能见度、气候、动植物均有影响,寻找合适的除尘设备,提高对微细粉尘的除尘效率,对安全和环境保护有着重要而深远的意义.该文利用脉冲滤筒除尘器对粒径分布为0.5-5μm的超细粉体进行净化实验.测试了除尘器净化效率、除尘器阻力及过滤风速等主要性能参数.实验结果说明:脉冲滤筒除尘器对于粒径为0.5-5μm超细粉体,在过滤风速为0.8-1.25m/min时,除尘器阻力小于300Pa,净化效率达99.9999%.得到结论:滤筒除尘器具有高除尘效率,低阻力损失,节约除尘系统的动力消耗的优点,有利于在超细粉体净化工艺中的应用.%With fast development of the Industry, more and more content and species of paniculate pollutants are in the air. The partieulate pollutants not only cause harm to the human health, but also have negative effect on the visibility , the climate , animals and plants. So it is important to safety and environmental protection that finding suitable dust collecting equipments and raising dust removal efficiency of fine dust particles.This paper was on the use of the pulse-jet cartridge dust collector to do the purifying experiment of the ultra-fine powder. The experimental tested the main characters of the pulse-jet cartridge dust collector, such as the purifying efficiency, the dust resistance and the filtering speed. The experimental results were that this study was used by the pulse-jet cartridge dust collector to purify 0.5μm - μm ultra-fine powders, tested the filtering speed were 0. 8 m/min-1.25m/min, dust resistance was less than 300Pa and the purifying efficiency was 99.9999% . At last, it comes to a conclusion; the pulse-jet cartridge filters are with the advantages of high efficiency, low pressure drop and save power to the dust removal system. The pulse-jet cartridge f dust

  6. Jet-cleaning experiment and simulation of a pulse-jet cartridge filter%脉冲喷吹滤筒除尘器喷吹清灰实验与数值模拟

    Institute of Scientific and Technical Information of China (English)

    袁彩云; 陈海焱; 李波

    2012-01-01

    通过喷吹实验台对φ147×1 000 mm滤筒的脉冲喷吹清灰过程进行了实验测试,运用数据采集系统得到了滤筒表面压力峰值的动态变化曲线图;并利用CFD模拟滤筒的清灰过程,计算过程采用非稳态计算方法,得到了不同喷吹时刻滤筒表面的压力峰值.在喷吹压力一定的条件下,沿滤筒长度方向上,正压力峰值到达时间是逐渐增加的;滤筒内压力峰值并非随着喷吹时间的增加而不断增大,当喷吹时间大于60 ms时,随着喷吹时间的增加压力峰值有下降趋势.模拟得到的压力峰值曲线与实验曲线变化趋势一致.%By testing the jet-cleaning process of a filter cartridge of 0147 x 1 000 mm in size on a jet experiment platform, obtains a dynamic change curve of peak pressure by means of a data collection system. Adopting CFD to simulate the jet-cleaning process of the filter using an unsteady calculation method, gains the peak pressures at different pulse-jet times. The occurring time of positive peak pressure is gradually increasing along the length direction of the cartridge under a given jet pressure. The increase of the peak pressure in cartridge does not increase with the jet time and the peak pressure has a decrease trend when the jet time is longer than 60 ms. The variation trend of the peak pressure curve from simulation is accordant with the one from the experiment.

  7. Micro-fluidic (Lab-on the- Chip) PCR Array Cartridge for Biological Screening in a Hand Held Device: FInal Report for CRADA no 264. PNNL-T2-258-RU with CombiMatrix Corp

    Energy Technology Data Exchange (ETDEWEB)

    Rainina, Evguenia I.

    2010-10-31

    The worldwide emergence of both new and old diseases resulting from human expansion and also human and materials mobility has and will continue to place stress on both medical and clinical diagnostics. The classical approach to bioagents detection involves the use of differential metabolic assays to determine species type in the case of most bacteria, or the use of cell culture and electron microscopy to diagnose viruses and some bacteria that are intracellular parasites. The long-term goal in bioagent detection is to develop a hand-held instrument featuring disposable cartridges which contain all the necessary reagents, reaction chambers, waste chambers, and micro-fluidics to extract, concentrate, amplify, and analyze nucleic acids. This GIPP project began development of a sensory platform using nucleic-acid based probes. Although research was not completed, initial findings indicated that an advanced sensing device could theoretically be built on a DNA/RNA-based technology platform.

  8. 冲击载荷作用下抽筒子疲劳寿命预测与试验验证%Fatigue Life Prediction and Test Validation of Cartridge Extractor Under Impact Load

    Institute of Scientific and Technical Information of China (English)

    胡慧斌; 候晓锋; 曹立军; 马吉胜

    2014-01-01

    在火炮发射过程中,抽筒子在冲击载荷作用下,经常产生疲劳断裂。为了实现有针对性的预防性维修,提出了一种冲击载荷作用下基于协同仿真技术的不规则零部件疲劳寿命预测方法。基于 Pro/E 和ADAMS建立了火炮射击过程的虚拟样机,并从定性和定量两个方面进行验证,仿真得到抽筒过程中抽筒子的载荷谱。结合有限元分析,计算抽筒子在静应力下的强度和寿命。在仿真载荷谱和有限元静应力分析的基础上,结合材料的S N 曲线,建立了抽筒子疲劳损伤与寿命预测模型,得到其危险部位的最小寿命。为了验证疲劳寿命预测模型的有效性,设计了由撞击试验台、传感器和信号测试分析系统组成的抽筒子疲劳寿命验证试验装置,根据抽筒过程和仿真载荷谱,合理确定撞击高度。试验结果验证了所建立的疲劳寿命预测模型的可信性。%Fatigue fracture is the familiar failure mode of cartridge extractor under impact load in the process of gun firing.A new kind of fatigue life prediction method of irregular compo-nents under impact load was put forward based on collaborative simulation technology.Virtual prototype in process of gun firing was established by use of Pro/E and ADAMS.It was verified with the help of qualitative and quantitative methods.The load spectrum of the cartridge ex-tractor during extracting cartridge was acquired by means of virtual prototype simulation.The strength and life of the extractor under static stress were calculated based on finite element a-nalysis.On the basis of the load spectrum and finite element analysis results,fatigue damage and life prediction model of the extractor was established and minimum lives of hazardous loca-tion were calculated.To verify the validity of fatigue life prediction model,a kind of fatigue life verification test device was designed,it consists of impact test platform

  9. 多孔介质散射器对滤筒除尘器清灰性能的影响研究%Effect of Diffusers Based on Porous Media on the Dust Cleaning in Cartridge Filters

    Institute of Scientific and Technical Information of China (English)

    李岚溪; 胥海伦; 刘东; 叶会文

    2016-01-01

    Due to the losing efficacy of the dust-cleaning at the top of the cartridge filters and the overlarge pressure at the bottom, this paper proposes to interfere the dust-cleaning fluid flow in the cartridge filters with gas diffusers based on porous media. The influence of the inlet-pressure and the diffusers based on porous media on these characteristics is simulated. Results are as follows. At the same inlet-pressure of the nozzles, the dust-cleaning performance shows the best when the porosity of the porous media is 0.87. At the same porosity of the porous media, the dust-cleaning performance shows the best when the inlet-pressure of the nozzles is 0.5MPa.%现有滤筒除尘器清灰存在滤筒顶部失效,底部压力太大的缺点,提出采用多孔介质气体散射器进行干扰滤筒除尘器内清灰的流场,并采用数值方法进行计算,结果表明:喷嘴进口压力相同情况下,多孔介质气流散射器孔隙率为0.87时清灰性能最好;多孔介质气流散射器孔隙率相同情况下,喷嘴进口压力为0.5MPa时清灰性能最好。

  10. Relational database cartridges and their efficiency in chemical sub-structure searching%子结构检索中关系数据库插件的使用和效率

    Institute of Scientific and Technical Information of China (English)

    王玉玲; 吴昊; 温浩

    2011-01-01

    采用关系数据库插件能够实现化合物描述符(FingerPrint)的生成、建立索引和化合物的子结构检索.本文以PubChem 有机化合物Molfile为数据源,在Oracle关系数据库上分别安装插件OrChem(JAVA)和Bingo(C++)构建了化合物分子结构数据库.本文从FingerPrint的构成和索引策略两方面讨论了OrChem和Bingo的主要差异,并选取10个特征化合物进行子结构检索测试.对存储40万种化合物的分子结构数据库的测试结果显示,OrChem可满足用户检索响应,Bingo则更为快捷.对于存储2600万种化合物的分子结构数据库,针对Bingo通过优化Oracle数据库内存管理、数据表结构、子结构预筛选参数,实现了满足用户的高效检索.%Relational database cartridge provides FingerPrint generation, indexing and molecular substructure searching. Two Oracle database cartridges, OrChem (JAVA) and Bingo (C++), are used in this work to develop the molecular structure database and its sub-structure search system with PubChem organic compound Molfile data. Differences between OrChem and Bingo on FingerPrint and Index strategy were discussed for 2-dimensional sub-structure searching. The efficiency of OrChem and Bingo on sub-structure searching was tested by using 10 typical query substructures on molecular structure databases of 400000 compounds and of 26000000 compounds, respectively. For the database of 400000 compounds, either OrChem or Bingo operates well enough for practical service, while Bingo shows higher efficiency. Bingo, for its capability on supporting the operation of larger database, operates successfully on the database of 26000000 compounds by configuration of memory management, table structure and sub-structure pre-screening parameters settings.

  11. Methods of analysis by the U.S. Geological Survey National Water Quality Laboratory; extraction of nitroaromatic compounds from water by polystyrene divinylbenzene cartridge and determination by high-performance liquid chromatography

    Science.gov (United States)

    Lindley, C.E.; Burkhardt, M.R.; DeRusseau, S.N.

    1994-01-01

    Organic explosives are determined in samples of ground water and surface water with emphasis on identifying and quantifying trinitrotoluene (TNT) metabolites. Water samples are filtered to remove suspended particulate material and passed through a polystyrene divinylbenzene-packed cartridge by a vacuum-extraction system. The target analytes subsequently are eluted with acetonitrile. A high-performance liquid chromatograph (HPLC) equipped with a photodiode-array detector is used for sample analysis. Analytes are separated on an octadecylsilane column using a methanol, water, and acetonitrile gradient elution. The compounds 2,4- and 2,6-dinitrotoluene are separated through an independent, isocratic elution. Method detection limits, on the basis of a 1-liter sample size, range from 0.11 to 0.32 microgram per liter. Recoveries averaged from 71 to 101 percent for 13 analytes in one set of HPLC-grade water fortified at about 1 microgram per liter. The method is limited to use by analysts experienced in handling explosive materials. (USGS)

  12. 某超高射速舰炮弹药筒膛内横断问题技术分析%Technical Analysis of Cartridge Breaking in Bore for Super-high Firing Rate Naval Gun

    Institute of Scientific and Technical Information of China (English)

    马献怀

    2015-01-01

    针对某超高射速舰炮及其弹道炮试验过程中出现的药筒膛内横断问题,通过现场勘测、理论分析和故障还原试验,确定了故障原因。根据故障机理,经技术攻关,提出了解决措施,经过后续多次射击试验验证,故障再未复现,证明了解决措施的可行有效。分析结果对解决速射火炮类似故障有重要的参考价值。%Aimed at the cartridge breaking problem occurred during the test of super-high firing rate naval gun and ballistic gun,the failure causes were determined by site investigation,theo-retical analysis and failure reproduction test.The solution was proposed based on the failure mechanism and technology research.The same failure hasn't occurred again during many firing test.The results show the solution is reasonable and feasible,which provides an important ref-erence value for solving similar failure of rapid-fire gun.

  13. Application of ion-exchange cartridge clean-up in food analysis. VI. Determination of six penicillins in bovine tissues by liquid chromatography-electrospray ionization tandem mass spectrometry.

    Science.gov (United States)

    Ito, Yuko; Goto, Tomomi; Oka, Hisao; Matsumoto, Hiroshi; Takeba, Kazue

    2004-07-09

    A multiresidue analytical method was developed for the quantification of benzylpenicillin (PCG), phenoxymethylpenicillin (PCV), oxacillin (MPIPC), cloxacillin (MCIPC), nafcillin (NFPC) and dicloxacillin (MDIPC) in bovine tissues using liquid chromatography- electrospray ionization tandem mass spectrometry (LC-ESI MS/MS) with a multiple reaction monitoring technique. Using the deuterated PCG and NFPC as internal standard was effective for improvement of repeatability and accuracy. We chose [M-H-141]- as a monitor ion of MRM analysis and [M-H]- as a precursor ion for each penicillin. Combination of an ion-exchange cartridge clean-up and ion-pair LC enable us to determine the residual penicillins using the standard curves made from standard solutions without the influence of sample matrix on the MS. The average recoveries of PCG, PCV, MPIPC, MCIPC, NFPC and MDIPC from bovine liver, kidney and muscle at the same concentrations as the tolerance levels of PCG (50 microg/kg) ranged from 77 to 101% with the coefficients of variation ranging from 0.7 to 4.2% (n = 5). The limits of quantification for the six penicillins were 2-10 microg/kg in bovine muscle, liver and kidney (S/N ratio >10).

  14. Application of ion-exchange cartridge clean-up in food analysis III. Determination of benzylpenicillin, phenoxymethyl-penicillin, oxacillin, cloxacillin, nafcillin and dicloxacillin in bovine liver and kidney by liquid chromatography with ultraviolet detection.

    Science.gov (United States)

    Ito, Y; Ikai, Y; Oka, H; Matsumoto, H; Kagami, T; Takeba, K

    2000-06-02

    A multiresidue analytical method was developed for the simultaneous determination of benzylpenicillin (PCG), phenoxymethylpenicillin (PCV), oxacillin (MPIPC), cloxacillin (MCIPC), nafcillin (NFPC) and dicloxacillin (MDIPC) in bovine liver and kidney. The method involves the use of an ion-exchange cartridge for sample clean-up followed by ion-pair high-performance liquid chromatography with ultraviolet detection. The recoveries of PCG, PCV, MPIPC, MCIPC, NFPC and MDIPC from bovine liver spiked at levels of 0.5 mg/kg and 0.1 mg/kg were in the range of 73-91% and 83-96% with coefficients of variation of 1.4-4.2% and 3.4-8.7%, respectively. For bovine kidney spiked at levels of 0.5 mg/kg and 0.1 mg/kg, the recoveries of these compounds were 79-92% and 82-92% with RSDs of 1.8-5.9% and 2.7-7.8%, respectively. The detection limits for the six penicillins were 0.02-0.05 mg/kg in bovine liver and kidney.

  15. A comparison of the Wheeler-Jonas model and the linear driving force at constant-pattern model for the prediction of the service time of activated carbon cartridges.

    Science.gov (United States)

    Grévillot, Georges; Marsteau, Stéphanie; Vallières, Cécile

    2011-05-01

    The linear driving force (LDF) model is applied to predict the service life of activated carbon cartridges. It is compared with the currently used Wheeler-Jonas equation, which results from a model of chemical reaction kinetics. The LDF model is based on a mass transfer model of adsorbate into the particle. The two models are studied in constant-pattern conditions. The properties of the two models are first clarified and then compared. It is shown that the Wheeler-Jonas equation leads to symmetrical breakthrough curves, whereas the constant-pattern LDF equation results in asymmetrical curves. Thus, the curvature of the isotherm has no influence on the shape of the Wheeler-Jonas curve. For the LDF breakthrough curve, it is shown that the asymmetry increases with the curvature of the isotherm. Wheeler-Jonas can be used with a Dubinin-Raduskevitch isotherm, whereas the LDF model analytical solution is valid for a Langmuir isotherm only. The LDF model can be used with the DR isotherm, but a numerical solution is required. At very low concentrations where the isotherm is linear, the constant pattern no longer exists and both models fail. The Dubinin-Raduskevitch isotherm must be fitted with a Langmuir isotherm to use the analytical solution of the LDF model.

  16. Ozone reaction with n-aldehydes (n=4-10), benzaldehyde, ethanol, isopropanol, and n-propanol adsorbed on a dual-bed graphitized carbon-carbon molecular sieve adsorbent cartridge.

    Science.gov (United States)

    McClenny, W A; Colón, M; Oliver, K D

    2001-09-21

    Ozone reacts with n-aldehydes (n=4-10), benzaldehyde, ethanol, isopropanol and n-propanol adsorbed on a dual-bed graphitized carbon-carbon molecular sieve adsorbent cartridge. Destruction of n-aldehydes increases with n number and with ozone concentration. In some sampling experiments both generation and destruction of n-aldehydes by ozone are observed. In field experiments the results of sample analysis for n-aldehydes and benzaldehyde are frequently not proportional to sample volume whereas results for toluene and isoprene, and sometimes for total carbon, are. A simple theory is developed to simulate the net result of three processes: the adsorption of compounds from an air stream onto a solid adsorbent, the generation of compounds by reaction of ozone with materials upstream of or on the adsorbent, and the destruction by ozone of pre-existing compounds and compounds adsorbed from the sample stream. The use of distributed volume pairs is recommended as a way to identify loss of sample integrity during air monitoring experiments.

  17. Determination of aminopolycarboxylic acids in river water by solid-phase extraction on activated charcoal cartridges and gas chromatography with mass spectrometric detection. Method performance characteristics and estimation of the uncertainty.

    Science.gov (United States)

    Jiménez, Juan J

    2013-04-03

    A new sample preparation procedure to determine aminopolycarboxylic acids (ethylenediaminetetraacetic acid, EDTA, nitrilotriacetic acid, NTA, diethylenetriaminepentaacetic acid, DTPA, and cyclohexanediaminetetraacetic acid, CDTA) in river water is described. The procedure consists of the solid-phase extraction of the aminopolycaroxyllic acids on activated charcoal cartridges after increasing the ionic strength and acidifying the sample. The extract was eluted with methanol and the analytes were methylated in presence of BF3/methanol to determine them by GC with mass spectrometric detection. Recoveries were higher than 90% with good repeatabilities and inter-day precision for concentrations close to quantification limits (about 10 μg L(-1)) and higher. It has been verified that the proposed method is robust according to the Youden and Steiner test and free of matrix effects arisen from the presence of organic matter and iron(III) as deduced from statistical tests. A bottom-up approach was followed to estimate the uncertainty of the measured concentration. At concentrations close to 10 μg L(-1) the most relevant step of the method is the calculus of the interpolated concentration which has a high value of relative standard uncertainty.

  18. Isolation of Diverse Structural Compartments of Natural Organic Matter from the Kolyma River Watershed in East Siberian Arctic Using DEAE-Cellulose, XAD-8 Resin, C18 and PPL Cartridges

    Science.gov (United States)

    Andzhushev, M.; Dubinenkov, I.; Holmes, R. M.; Hatfield, K.; Perminova, I.; Bulygina, E. B.; Konstantinov, A.

    2011-12-01

    Natural Organic Matter (NOM) is an essential part of the global carbon cycle and plays a significant role in transport of organic carbon from terrestrial ecosystems into the World Ocean. The Arctic region is one of the most vulnerable with respect to climate change. The Kolyma River is one of the great Arctic Rivers. The particular feature of the Kolyma River watershed is its location in the continuous permafrost zone. Hence, research on structural composition of NOM in the Kolyma River basin is very important for understanding the carbon flux and NOM transformations on the way from permafrost to the Arctic Ocean under conditions of the changing climate. The purpose of this work was to isolate diverse structural compartments of NOM from permafrost mud streams and freshwater environments of the Kolyma River basin suited for further structural studies using a suite of different sorbents. Another goal was to assess applicability of these sorbents for developing a NOM fluxmeter - passive device for in situ measurement of fluxes. The following sorbents were used in this study: diethylaminoethyl (DEAE) cellulose , XAD-8 resin, Varian Bond Elute PPL and C18-cartridges. The choice of the sorbents was based on the following considerations. DEAE-cellulose is an anion-exchanging resin. It is suited the best for isolation of negatively charged NOM constituents of high and low molecular weight which represent the major part of freshwater NOM. Given positive charge inherent within the sorbent, sorption of negatively charged compartments from natural water occurs under flow through conditions without any prior treatment. This makes the DEAE cellulose very promising for in situ applications (e.g., for fluxmeter). Amberlite XAD-8 is a macroreticular resin which is used as a part of the standard protocol of International Humic Substances Society for isolation of freshwater humic substances (HS). The XAD-8 resin represents a neutral hydrophobic polymer. As a result, for isolation of

  19. Evaluation of Thixocast Cartridge Stop Pawls.

    Science.gov (United States)

    1987-09-01

    34 rheocast " metal billet is used as the starting material. Rheocasting is a process in which material is cast in a mold while in a semi-liquid state...resulted from air entrained during rheocasting or thixocasting. The cracks observed visually and by magnetic particle inspection were found to be

  20. Next Generation LOCAD-PTS Cartridge Development

    Science.gov (United States)

    Morris, H.; Nutter, D.; Weite, E.; Wells, M.; Maule, J.; Damon, M.; Monaco, L.; Steele, A.; Wainwright, N.

    2008-01-01

    Future astrobiology exploration missions will require rapid, point-of-use techniques for surface science experiments and contamination monitoring. The Lab-On-a-Chip Application Development (LOCAD) team is developing operational instruments that advance spaceflight technologies to molecular-based methods. Currently, LOCAD-Portable Test System (PTS) is quantifying levels of the bacterial molecule endotoxin onboard the Internatioal Space Station. Future research and development will focus on more sensitive molecular techniques that expand the number of compounds detected to include beta-glucan from fungal cell walls.

  1. Indústria de cartucho de toner sob a ótica da remanufatura: estudo de caso de um processo de melhoria Remanufacturing of toner cartridge: a case study of a improvement process

    Directory of Open Access Journals (Sweden)

    Cícero Ferreira Fernandes Costa Filho

    2006-04-01

    Full Text Available Este trabalho apresenta um estudo de caso de um processo de melhoria aplicado a uma indústria de remanufatura de cartuchos de toner. Inicialmente, é feita uma abordagem do processo de remanufatura procurando salientar as principais características que o diferenciam de um processo de manufatura convencional e a importância do mesmo diante das preocupações ambientais atuais. Através de três indicadores de desempenho propostos no trabalho fez-se um diagnóstico do processo de remanufatura quanto ao aproveitamento de peças recolhidas do campo, atendimento de pedidos dos clientes e quantidade de defeitos. No diagnóstico inicial realizado, os valores obtidos para esses critérios situaram-se abaixo das metas estabelecidas na empresa. Através da metodologia PDCA, identificaram-se oportunidades de melhorias em pontos críticos do processo de fabricação. A implantação dessas melhorias resultou em ganhos nos indicadores de desempenho da ordem de 12%. Algumas ferramentas clássicas foram utilizadas para auxiliar na implementação da metodologia PDCA destacando-se brainstorming, diagrama de Ishikawa e Controle Estatístico de Processo.This paper presents an improvement process applied in one remanufacturing toner cartridge industry. It, initially, presents a mapping of the stages of this process by attempting to highlight the main characteristics, which distinguish it from a conventional manufacturing process and emphasizes its importance as an of eco-efficient process aiming at achieving sustainable development. Through three performance indicators proposed by the work, a diagnosis of the existing process was carried out as to the reuse of parts gasthered in the field, fulfilment of customers'orders and quantity of production faults. At the initial diagnosis carried out, the values obtained for theses criteria were located below the established targets proposed by the company. Through the PDCA tool, improvement opportunities in critical

  2. 基于二通插装阀的换辊装置液压控制回路故障分析及优化%Fault Analysis and Optimization of Hydraulic Control Loop Based on 2-way Cartridge Valve for Roll Change Device

    Institute of Scientific and Technical Information of China (English)

    李宇林

    2016-01-01

    简要阐述了某万能轧机换辊装置的工艺要求、原设计的液压控制回路及二通插装阀的工作原理,对使用过程中的故障进行了分析与排查,并提出了优化后的控制回路。从使用效果来看,回路优化后故障彻底消除。%The technical requirements of roll change device for a certain universal mill and the original hydraulic control loop, and the working principle of 2-way cartridge valve were described.Further analysis and survey on the fault in operation were made and the optimized control loop was put forward.In effect, after optimization, the fault in application is removed completely.

  3. High-throughput cytochrome P450 (CYP) inhibition screening via cassette probe-dosing strategy. I. Development of direct injection/on-line guard cartridge extraction/tandem mass spectrometry for the simultaneous detection of CYP probe substrates and their metabolites.

    Science.gov (United States)

    Bu, H Z; Magis, L; Knuth, K; Teitelbaum, P

    2000-01-01

    A highly efficient direct injection/on-line guard cartridge extraction/tandem mass spectrometry (DI-GCE/MS/MS) method utilizing electrospray polarity switching was developed for the simultaneous detection of probe substrates and marker metabolites of seven human hepatic cytochrome P450 (CYP) isozymes: CYP1A2, 2A6, 3A4, 2C9, 2C19, 2D6 and 2E1. Microsomal incubations were terminated with formic acid, centrifuged, and the resulting supernatants were injected for analysis by DI-GCE/MS/MS. This method employed an extremely short C(18) cartridge (4 mm in length) which allowed rapid cleanup of sample matrices while retaining the analytes an appropriate time (2. 0-2.2 min). From 1.5 to 2.7 min the effluent was directed to the mass spectrometer for detection otherwise diverted to waste. As a result of the efficient on-line extraction, matrix (e.g., salts and proteins) suppression was minimized. In addition, no visible source contamination was observed and system performance (chromatographic and mass spectrometric) did not significantly deteriorate after 500 consecutive injections. Electrospray polarity switching was strategically executed on a Micromass Quattro II mass spectrometer by establishing dummy ion transitions to protect the analytes from the interference of the overwhelming noise which was unavoidable for the first transition scanned following each polarity switch. This unique strategy led to the simultaneous detection of seven CYP probe substrates and seven corresponding marker metabolites (12 by positive mode and 2 by negative mode).

  4. Thermal compatibility studies of unirradiated UMo alloys dispersed in aluminum

    Science.gov (United States)

    Lee, Don Bae; Kim, Ki Hwan; Kim, Chang Kyu

    1997-11-01

    The thermal compatibility of centrifugally atomized UMo alloys with aluminium has been studied. The results of the investigations show that the U-2 wt% Mo/aluminum dispersions increase in volume by 26% at 400°C after 2000 h. This large volume change is mainly due to the formation of voids and cracks resulting from nearly complete interdiffusion of UMo and aluminum. No significant dimensional changes occur in the U-10 wt% Mo/aluminum dispersions. Interdiffusion between U-10 wt% Mo and aluminum is found to be minimal. The different diffusion behavior is primarily due to the fact that U-10 wt% Mo particles are much more supersaturated with substitutional molybdenum than U-2 wt% Mo particles. The aluminum diffuses into the U-2 wt% Mo particles relatively rapidly along grain boundary with nearly pure uranium, forming UAl 3 almost fully throughout the 2000 h anneal, whereas the molybdenum supersaturated in the U-10 wt% Mo particles inhibits the diffusion of aluminum atoms. U-10 wt% Mo displays superior thermal compatibility with aluminum compared to U-2 wt% Mo.

  5. Plastic flow properties and fracture toughness characterization of unirradiated and irradiated tempered martensitic steels

    Science.gov (United States)

    Spätig, P.; Bonadé, R.; Odette, G. R.; Rensman, J. W.; Campitelli, E. N.; Mueller, P.

    2007-08-01

    We investigate the plastic flow properties at low and high temperature of the tempered martensitic steel Eurofer97. We show that below room temperature, where the Peierls friction on the screw dislocation is active, it is necessary to modify the usual Taylor's equation between the flow stress and the square root of the dislocation density and to include explicitly the Peierls friction stress in the equation. Then, we compare the fracture properties of the Eurofer97 with those of the F82H steel. A clear difference of the fracture toughness-temperature behavior was found in the low transition region. The results indicate a sharper transition for Eurofer97 than for the F82H. Finally, the shift of the median toughness-temperature curve of the F82H steel was determined after two neutron irradiations performed in the High Flux Reactor in Petten.

  6. Distribution of properties in nuclear reactor vessel shells in the unirradiated state

    Science.gov (United States)

    Skundin, M. A.; Chernobaeva, A. A.; Zhurko, D. A.; Krasikov, E. A.; Medvedev, K. I.

    2013-04-01

    The distributions of the chemical composition, the strength characteristics, and critical ductile-brittle transition temperature T cr are studied in the axial, radial, and tangential directions of the material of a test ring cut from a standard forging used for a VVER-1000 reactor vessel shell. The values of T cr of specimens cut from the test ring are shown to be well below those of the internal volume of the shell, which can explain the substantial scatter of the results obtained on reference specimens cut from the base metal.

  7. Desalting with solid phase extraction cartridge and using GF-AAS for the determination of lead in soy sauce%固相萃取柱脱盐-石墨炉原子吸收法测定酱油中铅

    Institute of Scientific and Technical Information of China (English)

    毛红; 巩俐彤; 沙博郁; 孙开奇; 张妮娜

    2011-01-01

    Objective To establish a solid phase extraction ( SPE) with atom absorption spectrometoy (AAS) for the determination of lead in soy sauce samples. Methods The samples were pretreated by microwave digestion. After the digested solution being adjusted to Ph 5.5 by ammonium acetate, the solution was then passed through a DigiSEP-Blue cartridge pretreated by 5 ml of 1 mol/L ammonium acetate for the removal of large amount of salt. The eluate from the DigiSEP-Blue cartridge washed by 8ml of 2 mol/L nitric acid and 2 ml of water was directly used for the analysis of lead on AAS. Results More than 98% of salt in soy sauce samples could be separated with lead by DigiSEP-Blue cartridge. The recoveries (n =7) of lead in two different samples spiked with 10 and 30 ng/ml of lead were 91. 3% -95.1% and 97.9% -98.6% , respectively. The relative standard deviations (USD) were lower than 7.0 %. The limit of detection was 1.33 ng/g. Conclusion The method was accurate and sensitive, suitable for the accurate determination of lead in soy sauce with high levels of salt.%目的 建立固相萃取柱脱盐—石墨炉原子吸收法测定酱油中铅的方法.方法 酱油经微波消解后,消解液用乙酸铵调节至pH≈5.5,过经用5 ml 1 mol/L乙酸铵活化后的DigiSEP-Blue柱,将被测元素铅吸附与基体中高盐分离,再分别用8 ml 2 mol/L硝酸、2 ml纯水洗脱,应用石墨炉原子吸收法测定洗脱液中铅含量.结果 用固相萃取柱可将酱油中98%以上的钠盐与被测元素铅分离,消除了石墨炉原子吸收分光光度计测定铅时的基体干扰.低、高两个铅浓度(10和30 ng/ml)的加标平均回收率(n=7)分别为91.3% ~95.1%,97.9%~98.6%,相对标准偏差为2.1% ~7.0%,检出限为1.33 ng/g.结论方法准确、灵敏度高,适于高盐样品酱油中铅含量的测定.

  8. Lubrication in the Drawing of Steel Cartridge Cases

    Science.gov (United States)

    1945-11-01

    loss offensive odor than the sulfurized tallow and water, it was still very mossy and disagroeable. In addition, the heat generated during drawing is...then to add the sulfurizod additive. A dispersion containing 4% soap, 12% tallow , 3-4% of finoly divided filler and 0,5% or a reactive sulfurizod fatty...operations between draws. F, Sulfide Coating Quite early in the steel case program a sulfurized tallow containing small amounts of water was used in the

  9. 42 CFR 84.1154 - Canister and cartridge requirements.

    Science.gov (United States)

    2010-10-01

    ..., and Mist; Pesticide; Paint Spray; Powered Air-Purifying High Efficiency Respirators and Combination... are used in parallel, their resistance to airflow shall be essentially equal. (b) The color...

  10. 21 CFR 520.1450b - Morantel tartrate cartridge.

    Science.gov (United States)

    2010-04-01

    ... grazing season. (2) Indications for use. For control of the adult stage of the following gastrointestinal nematode infections in weaned calves and yearling cattle weighing a minimum of 200 pounds: Ostertagia spp... dependent upon continuous control of the gastrointestinal parasites for approximately 90 days...

  11. 77 FR 11586 - Certain Toner Cartridges and Components Thereof

    Science.gov (United States)

    2012-02-27

    ... Cumberland Point Drive, Suite 21, Marietta, GA 30067. E-Max Group, Inc., d/b/a Databazaar.com , 12070 Miramar... Secretary, U.S. International Trade Commission, 500 E Street SW., Room 112, Washington, DC 20436, telephone.... International Trade Commission, 500 E Street SW., Suite 401, Washington, DC 20436; and (3) For the...

  12. Creation of Scalable, Cartridge-Based Microreactor Reformers

    Science.gov (United States)

    2010-10-31

    obtained for: i) Flow through a single cordierite channel, ii) 5x5 microchanncl reactor with tracer injection through 12 channels, iii) 5x5 microchannel ...channel, ii) 5x5 microchannel reactor with gas injection through 12 channels, iii) 5x5 microchannel reactor with gas injection through 13 channels. 300...mid-point of the reactor and spanned the majority of the microchannel network with a maximum external temperature of 430°C. As ER is reduced, the hot

  13. Development Study of Cartridge/Crucible Tube Materials

    Science.gov (United States)

    McKechnie, Timothy N.; ODell, Scott J.

    1998-01-01

    The limitations of traditional alloys and the desire for improved performance for components is driving the increased utilization of refractory metals in tile space industry. From advanced propulsion systems to high temperature furnace components for microgravity processing, refractory metals are being used for their high melting temperatures and inherent chemical stability. Techniques have been developed to produce near net shape refractory metal components utilizing vacuum plasma spraying. Material utilization is very high, and laborious machining can be avoided. As-spray formed components have been tested and found to perform adequately. However, increased mechanical and thermal properties are needed. To improve these properties, post processing thermal treatments such as hydrogen sintering and vacuum annealing have been performed. Components formed from alloys of tungsten, rhenium, tantalum, niobium, and molybdenum are discussed and a metallurgical analyses detailing the results are presented. A qualitative comparison of mechanical properties is also included.

  14. Rapid Peptide Reagent Isolation in a Disposable Microfluidic Cartridge

    Science.gov (United States)

    2010-09-01

    a format that could serve as a single resource for many ligand isolation applications has not been reported. Through the 6.1 research component of...Kratzner, R.; Kolmar, H. The Cystine Knot of a Squash-type Protease Inhibitor as a Structural Scaffold for Escherichia coli Cell Surface Display of

  15. RAMGEN ROTOR CARTRIDGE FOR THE PRE-PROTOTYPE RAMGEN ENGINE

    Energy Technology Data Exchange (ETDEWEB)

    Aaron Koopman

    2003-09-01

    The research and development of a unique combustion engine is presented. The engine converts the thrust from ramjet modules located on the rim of a disk into shaft torque, which in turn can be used for electrical power generation or mechanical drive applications. A test program was undertaken that included evaluation of the pre-prototype engine and incorporation of improvements to the thrust modules and supporting systems. Fuel mixing studies with vortex generators and bluff body flame holders demonstrated the importance of increasing the shear-layer area and spreading angle to augment flame volume. Evaluation of flame-holding configurations (with variable fuel injection methods) concluded that the heat release zone, and therefore combustion efficiency, could be manipulated by judicious selection of bluff body geometry, and is less influenced by fuel injection distribution. Finally, successful operation of novel fuel and cooling air delivery systems have resolved issues of gas (fuel and air) delivery to the individual rotor segments. The lessons learned from the pre-prototype engine are currently being applied to the development of a 2.8MW engine.

  16. Automated microfluidic cartridges for point-of-care cell counting

    CSIR Research Space (South Africa)

    Smith, S

    2016-10-01

    Full Text Available ('�0,&52)/8,',&�&$575,'*(6�)25�� 32,17�2)�&$5(�&(//�&2817,1*� 6��6PLWK���3��0DG]LYKDQGLOD���5��6HZDUW���8��*RYHQGHU���+��%HFNHU���.��/DQG���DQG� 3��5RX[���&RXQFLO�IRU�6FLHQWLILF�DQG�,QGXVWULDO�5HVHDUFK��6287+�$)5,&$�DQG� �PLFURIOXLGLF�&KLS6KRS�*PE+��*(50$1<� � $%675$&7� 7KLV� ZRUN...�� ³&KDUDFWHUL]DWLRQ� RI�PLFURIOXLGLF� FRPSRQHQWV� IRU� ORZ�FRVW� SRLQW�RI�FDUH�GLDJQRVWLFV�´�3URFHHGLQJV�RI�0LFUR7$6�FRQIHUHQFH��)UHLEXUJ��*HUPDQ\\����������� ������ >�@� 6��6PLWK��7��1DLGRR��(��'DYLHV��/�� �)RXULH��=��1[XPDOR��+��6ZDUW��3��0DUDLV��.��/DQG�DQG�3...

  17. Nanoindentation measurements of the mechanical properties of zirconium matrix and hydrides in unirradiated pre-hydrided nuclear fuel cladding

    Science.gov (United States)

    Rico, A.; Martin-Rengel, M. A.; Ruiz-Hervias, J.; Rodriguez, J.; Gomez-Sanchez, F. J.

    2014-09-01

    It is well known that the mechanical properties of the nuclear fuel cladding may be affected by the presence of hydrides. The average mechanical properties of hydrided cladding have been extensively investigated from a macroscopic point of view. In addition, the mechanical and fracture properties of bulk hydride samples fabricated from zirconium plates have also been reported. In this paper, Young's modulus, hardness and yield stress are measured for each phase, namely zirconium hydrides and matrix, of pre-hydrided nuclear fuel cladding. To this end, nanoindentation tests were performed on ZIRLO samples in as-received state, on a hydride blister and in samples with 150 and 1200 ppm of hydrogen homogeneously distributed along the hoop direction of the cladding. The results show that the measured mechanical properties of the zirconium hydrides and ZIRLO matrix (Young's modulus, hardness and yield stress) are rather similar. From the experimental data, the hydride volume fraction in the cladding samples with 150 and 1200 ppm was estimated and the average mechanical properties were calculated by means of the rule of mixtures. These values were compared with those obtained from ring compression tests. Good agreement between the results obtained by both methods was found.

  18. Properties of unirradiated HTGR core support and permanent side reflector graphites: PGX, HLM, 2020, and H-440N

    Energy Technology Data Exchange (ETDEWEB)

    Engle, G.B.

    1977-05-01

    Candidate materials for HTGR core supports and permanent side reflectors--graphite grades 2020 (Stackpole Carbon Company), H-440N (Great Lakes Carbon Corporation), PGX (Union Carbide Corporation), and HLM (Great Lakes Carbon Corporation)--are described and property data are presented. Properties measured are bulk density; tensile properties including ultimate strength, modulus of elasticity, and strain at fracture; flexural strength; compressive properties including ultimate strength, modulus of elasticity, and strain at fracture; and chemical impurity content.

  19. Metaphase yields from staphylococcal enterotoxin A stimulated peripheral blood lymphocytes of unirradiated and irradiated aged rhesus monkeys

    Science.gov (United States)

    Hill, F. S.; Cox, A. B.; Salmon, Y. L.; Cantu, A. O.; Lucas, J. N.

    1994-01-01

    The mitogen phytohemagglutinin (PHA) works well in both human and cynomolgus monkey (Macaca fascicularis) lymphocyte cultures to stimulate T cell proliferation. T cells from rhesus monkeys (Macaca mulatta) are less responsive than human cells, producing few metaphases when thousands are required, e.g. in biological dosimetry studies. We show that staphylococcal enterotoxin A (SEA), one of the most potent mitogens known, at a concentration of 0.5 microgram/ml stimulated peripheral lymphocytes to grow with a mitotic index (MI) averaging 0.13 metaphases/cell in old, irradiated rhesus macaques. This was significantly greater (p < 0.001) than that produced by PHA (MI < 0.01) in lymphocytes from the same animals. Whole blood was cultured for 96, 120 and 144 h for five irradiated individuals and for two controls. All cells cultured with SEA produced a high MI with a peak response at 120 h whereas the same cultures showed low MI for each PHA stimulated culture.

  20. Metaphase yields from staphylococcal enterotoxin A stimulated peripheral blood lymphocytes of unirradiated and irradiated aged rhesus monkeys

    Energy Technology Data Exchange (ETDEWEB)

    Hill, F.S.; Cantu, A.O.; Lucas, J.N. (Lawrence Livermore National Lab., CA (United States)); Cox, A.B.; Salmon, Y.L. (Air Force Armstrong Lab., Brookes AFB, TX (United States))

    1994-10-01

    The mitogen phytohemagglutinin (PHA) works well in both human and cynomolgus monkey (Macaca fascicularis) lymphocyte cultures to stimulate T cell proliferation. T cells from rhesus monkeys (Macaca mulatta) are less responsive than human cells, producing few metaphases when thousands are required, e.g. in biological dosimetry studies. We show that staphylococcal enterotoxin A (SEA), one of the most potent mitogens known, at a concentration of 0.5 [mu]g/ml stimulated peripheral lymphocytes to grow with a mitotic index (MI) averaging 0.13 metaphases/cell in old, irradiated rhesus macaques. This was significantly greater (p < 0.001) that that produced by PHA (M1<0.01) in lymphocytes from the same animals. Whole blood was cultured for 96, 120 and 144 h for five irradiated individuals and for two controls. All cells cultured with SEA produced a high MI with a peak response at 120 h whereas the same cultures showed low MI for each PHA stimulated culture. (author).

  1. Nanoindentation measurements of the mechanical properties of zirconium matrix and hydrides in unirradiated pre-hydrided nuclear fuel cladding

    Energy Technology Data Exchange (ETDEWEB)

    Rico, A., E-mail: alvaro.rico@urjc.es [DIMME, Departamento de Tecnología Mecánica, Universidad Rey Juan Carlos, c/Tulipán s/n, E-28933 Móstoles, Madrid (Spain); Martin-Rengel, M.A., E-mail: mamartin@mater.upm.es [Departamento de Ciencia de los Materiales, UPM, E.T.S.I. Caminos, Canales y Puertos, Profesor Aranguren SN, E-28040 Madrid (Spain); Ruiz-Hervias, J., E-mail: jesus.ruiz@upm.es [Departamento de Ciencia de los Materiales, UPM, E.T.S.I. Caminos, Canales y Puertos, Profesor Aranguren SN, E-28040 Madrid (Spain); Rodriguez, J. [DIMME, Departamento de Tecnología Mecánica, Universidad Rey Juan Carlos, c/Tulipán s/n, E-28933 Móstoles, Madrid (Spain); Gomez-Sanchez, F.J., E-mail: javier.gomez@amsimulation.com [Advanced Material Simulation, S.L, Madrid (Spain)

    2014-09-15

    It is well known that the mechanical properties of the nuclear fuel cladding may be affected by the presence of hydrides. The average mechanical properties of hydrided cladding have been extensively investigated from a macroscopic point of view. In addition, the mechanical and fracture properties of bulk hydride samples fabricated from zirconium plates have also been reported. In this paper, Young’s modulus, hardness and yield stress are measured for each phase, namely zirconium hydrides and matrix, of pre-hydrided nuclear fuel cladding. To this end, nanoindentation tests were performed on ZIRLO samples in as-received state, on a hydride blister and in samples with 150 and 1200 ppm of hydrogen homogeneously distributed along the hoop direction of the cladding. The results show that the measured mechanical properties of the zirconium hydrides and ZIRLO matrix (Young’s modulus, hardness and yield stress) are rather similar. From the experimental data, the hydride volume fraction in the cladding samples with 150 and 1200 ppm was estimated and the average mechanical properties were calculated by means of the rule of mixtures. These values were compared with those obtained from ring compression tests. Good agreement between the results obtained by both methods was found.

  2. Kinetic analysis for non-isothermal decomposition of un-irradiated and gamma-irradiated anhydrous cadmium nitrate

    Energy Technology Data Exchange (ETDEWEB)

    Culas, S.; Samuel, J. [Mar Ivanios College, Kerala (India). Dept. of Chemistry

    2014-04-01

    The thermal decomposition of untreated and γ-irradiated samples of anhydrous cadmium nitrate was performed under non-isothermal conditions at different heating rates (5, 10, 15 and 20 C min{sup -1}). The results showed that the decomposition proceeds in one major step with the formation of cadmium oxide as solid residue. The data were analysed by using both isoconversional and non-isoconversional methods. The activation energy was calculated by various model-free isoconversional methods: Flynn-Wall-Ozawa (FWO), Kissinger-Akahira-Sunose (KAS) and Friedman (FR) methods. Irradiation enhances the decomposition and the effect increases with the irradiation dose. The activation energy decreases on irradiation. The appropriate conversion model for the thermal decomposition process selected by means of the master-plot method agrees with phase boundary reaction with spherical symmetry (R3 mechanism) for both untreated and irradiated salts at all heating rates. (orig.)

  3. Unirradiated cells rescue cells exposed to ionizing radiation: Activation of NF-κB pathway in irradiated cells

    Energy Technology Data Exchange (ETDEWEB)

    Lam, R.K.K. [Department of Physics and Materials Science, City University of Hong Kong (Hong Kong); Han, Wei [Center of Medical Physics and Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031 (China); Yu, K.N., E-mail: peter.yu@cityu.edu.hk [Department of Physics and Materials Science, City University of Hong Kong (Hong Kong); State Key Laboratory in Marine Pollution, City University of Hong Kong (Hong Kong)

    2015-12-15

    Highlights: • Rescue effect was observed in both irradiated and HeLa and NIH/3T3 cells. • Novel setup and procedures to separate the rescue signals and the bystander signals. • Confirmed activation of NF-κB pathway in rescue effect using activation inhibitor. • Confirmed activation of NF-κB pathway in rescue effect using anti-NF-κB p65 antibody. - Abstract: We studied the involvement of NF-κB pathway activation in the rescue effect in HeLa and NIH/3T3 cells irradiated by α particles. Firstly, upon irradiation by 5 cGy of α particles, for both cell lines, the numbers of 53BP1 foci/cell at 12 h post-irradiation were significantly smaller when only 2.5% of the cell population was irradiated as compared to 100% irradiation, which demonstrated the rescue effect. Secondly, we studied the effect of NF-κB on the rescue effect through the use of the NF-κB activation inhibitor BAY-11-7082. Novel experimental setup and procedures were designed to prepare the medium (CM) which had conditioned the bystander cells previously partnered with irradiated cells, to ensure physical separation between rescue and bystander signals. BAY-11-7082 itself did not inflict DNA damages in the cells or have effects on activation of the NF-κB response pathway in the irradiated cells through direct irradiation. The rescue effect was induced in both cell lines by the CM, which was abrogated if BAY-11-7082 was added to the CM. Thirdly, we studied the effect of NF-κB on the rescue effect through staining for phosphorylated NF-κB (p-NF-κB) expression using the anti-NF-κB p65 (phospho S536) antibody. When the fraction of irradiated cells dropped from 100% to 2.5%, the p-NF-κB expression in the cell nuclei of irradiated NIH/3T3 cells increased significantly, while that in the cell nuclei of irradiated HeLa cells also increased although not significantly. Moreover, the p-NF-κB expression in the cell nuclei of irradiated HeLa cells and NIH/3T3 cells treated with CM also increased significantly.

  4. Leaching action of EJ-13 water on unirradiated UO{sub 2} surfaces under unsaturated conditions at 90{degree}C: Interim report

    Energy Technology Data Exchange (ETDEWEB)

    Wronkiewicz, D.J.; Bates, J.K.; Gerding, T.J.; Veleckis, E.; Tani, B.S.

    1991-07-01

    A set of experiments, based on the application of the Unsaturated Test method to the reaction of UO{sub 2} with EJ-13 water, has been conducted over a period of 182.5 weeks. One half of the experiments have been terminated, while one half are still ongoing. Solutions that have dripped from UO{sub 2} specimens have been analyzed for all experiments, while the reacted UO{sub 2} surfaces have been examined for only the terminated experiments. A pulse of uranium release from the UO{sub 2} solid, in conjunction with the formation of dehydrated schoepite on the surface of the UO{sub 2}, was observed during the 39- to 96-week period. Thereafter, the uranium release decreased and a second set of secondary phases was observed. The latter phases incorporate cations from the EJ-13 water and include boltwoodite, uranophane, sklodowskite, compreignacite, and schoepite. The experiments are being continued to monitor for additional changes in solution composition and secondary phase formation, and have now reached the 319-week period. 9 refs., 17 figs., 25 tabs.

  5. NSRR experiment with un-irradiated uranium-zirconium hydride fuel. Design, fabrication process and inspection data of test fuel rod

    Energy Technology Data Exchange (ETDEWEB)

    Sasajima, Hideo; Fuketa, Toyoshi; Ishijima, Kiyomi; Kuroha, Hiroshi; Ikeda, Yoshikazu [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Aizawa, Keiichi

    1998-08-01

    An experiment plan is progressing in the Nuclear Safety Research Reactor (NSRR) to perform pulse-irradiation with uranium-zirconium hydride (U-ZrH{sub x}) fuel. This fuel is widely used in the training research and isotope production reactor of GA (TRIGA). The objectives of the experiment are to determine the fuel rod failure threshold and to investigate fuel behavior under simulated reactivity initiated accident (RIA) conditions. This report summarizes design, fabrication process and inspection data of the test fuel rods before pulse-irradiation. The experiment with U-ZrH{sub x} fuel will realize precise safety evaluation, and improve the TRIGA reactor performance. The data to be obtained in this program will also contribute development of next-generation TRIGA reactor and its safety evaluation. (author)

  6. A Study of False-Positive and False-Negative Error Rates in Cartridge Case Comparisons

    Science.gov (United States)

    2014-04-07

    Defense Biometrics and Forensics Office, Assistant Secretary of Defense (Research and Engineering), through the U.S. Department of Energy Contract No...official policies, either expressed or implied, of the Defense Biometrics and Forensics Office, Defense Forensic Science Center, or the U.S...Acknowledgements This work was supported by Defense Biometrics and Forensics Office through the U.S. Department of Energy under Contract No. DE-AC02

  7. Canon Promoting Original Toner Cartridges%佳能促销原装硒鼓

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    缤纷的夏日即将到来,如果能拥有一款时尚炫彩私人CD箱,在这个夏天珍藏你最爱的音乐专辑或DVD大片,想必会是个不错的选择。从即日起到6月30日,佳能在全国范围内正在开展主题为“给礼更给力”的原装硒鼓促销活动。

  8. 硒鼓的使用与保养%The Use & Overhaul of Toner Cartridges

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    硒鼓的基材一般是铝制的,基材上涂感光材料。根据感光材料的不同,可分为三种:OPC鼓(有机光导材料)、硒鼓(Se硒)和陶瓷鼓(a—si陶瓷)。从使用寿命上说,OPC鼓的寿命较短,一般为3000页左右,Se鼓寿命约9000页左右,a—si鼓寿命长,可达90000页,价格方面根据使用寿命的不同差别大:

  9. 78 FR 23955 - Certain Toner Cartridges and Components Thereof; Commission Determination Not To Review an...

    Science.gov (United States)

    2013-04-23

    ... Express LLC d/b/a Discount Office Items; Green Project, Inc.; GreenLine Paper Co., Inc.; Myriad Greeyn LLC... defaulting respondents, and the imposition of a bond of 100 percent of entered value during the period of...). During this period, the subject articles would be entitled to enter the United States under bond, in an...

  10. Microfluidic cartridge with integrated array of amorphous silicon photosensors for chemiluminescence detection of viral DNA

    Directory of Open Access Journals (Sweden)

    M. Zangheri

    2016-03-01

    With this system, taking advantage of oligoprobes specificity, chemiluminescence detectability, and photosensor sensitivity, accurate quantification of target analytes down to 70 pmol L−1 was obtained for each B19 DNA genotype, with high specificity and multiplexing ability. Results confirm the good detection capabilities and assay applicability of the proposed system, prompting the development of innovative portable analytical devices with enhanced sensitivity and multiplexed capabilities.

  11. An On-Chip Nano-Plasmonics Based Urine Protein Assay Cartridge Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Long-term exposure to microgravity and radiation during space exploration can pose a critical threat to the health of a flight crew. Real-time monitoring of urine...

  12. Determination of Nonpropagation Distances for 25-mm XM792 HEI-T cartridges

    Science.gov (United States)

    1983-02-01

    mix; Item % by weight 97/3 RDX/ wax 64 Aluminum powder 35 Graphite and/or calcium stearate 1 Tracer composition: Pellet types (% by weight) Item...Magnesium (16 granulation) Magnesium (five-micron size) PTFE VITON-A Strontium nitrate Graphite Carbon black. Ethyl cellulose Weight: grams...CM i-J 3 H •H G © 19 HEI EXPLOSIVE MIX 97/3 RDX/ WAX ALUMINUM POWDER- GRAPHITE AND/OR— CALCIUM STEARATE 3 EACH, 3.350 GRAM TYPE I PELLETS

  13. Fibrillation of Commercial Acrylic Fiber for Use in Combustible Cartridge Cases

    Science.gov (United States)

    1983-03-01

    mesh - 5.4% Conclusion Fibrillation poor when viewed under microscope; not usable for process. Experiment 8 Material Used du Pont Orlon, 5 denier...to the solution. 2 Crystals, technical grade, Witco Chemical, Brooklyn , N. Y. 11231. 52 Ai The material was microscopically checked at 10-minute

  14. A New Hard Coat on Cover Layer for Cartridge-Free Blu-ray Disc

    Science.gov (United States)

    Han, Mi Young; Kang, Tae-Sik; Lee, Seong-Keun; Jang, Sung Hoon; Seo, Hun; Lee, Chang-Ho

    2004-07-01

    A new UV-curable hard coat resin with an excellent antifouling property has been developed. A 3-μm-thick hard coat layer was stacked onto a 97-μm-thick cover layer by spin coating. The characteristics of the hard coat layer, such as pencil hardness, microscratch resistance, adhesion, water contact angle and jitter, have been investigated.

  15. 77 FR 4362 - Certain Toner Cartridges and Components Thereof; Receipt of Complaint; Solicitation of Comments...

    Science.gov (United States)

    2012-01-27

    ... Office Items) of WI; Do It Wiser LLC (d/b/a Image Toner) of GA; E-Max Group, Inc. (d/b/a Databazaar.com..., Secretary to the Commission, U.S. International Trade Commission, 500 E Street SW., Washington, DC 20436... E Street SW., Washington, DC 20436, telephone (202) 205-2000. General information concerning...

  16. 77 FR 12325 - Certain Toner Cartridges and Components Thereof Corrected Notice of Institution of Investigation

    Science.gov (United States)

    2012-02-29

    ... 30067. E-Max Group, Inc., d/b/a Databazaar.com , 12070 Miramar Parkway, Miramar, FL 33025. ] Green....m. to 5:15 p.m.) in the Office of the Secretary, U.S. International Trade Commission, 500 E Street... Commission, 500 E Street, SW., Suite 401, Washington, DC 20436; and (3) For the investigation so...

  17. 78 FR 40506 - Certain Toner Cartridges and Components Thereof; Issuance of General Exclusion Order and Cease...

    Science.gov (United States)

    2013-07-05

    ... Marietta, Georgia; E-Max Group, Inc. (d/b/a Databazaar.com ) of Miramar, Florida; IJSS Inc. (d/b/a Toner... domestic respondents Standard Image USA, Inc.; Printronic Corporation; Nukote, Inc.; Do It Wiser LLC; E-Max... General Counsel, U.S. International Trade Commission, 500 E Street SW., Washington, DC 20436,...

  18. Combustible Cartridge Cases, an Account of the Current Technology and Proposals for Future Development.

    Science.gov (United States)

    1986-10-01

    Division 43 Library, Materials Research Laboratorios .4 Librarian, Defence Signals Directorate library, Office of Defence Producton 4t Director...include inherent lack of mechanical strength, low porosity, vulnerability to penetration of water and water vapour, and problems related to materials ...8217- firing, supplement the energy of the propellant and lower wear and erosion of the tube. However, these materials lack the mechanical properties

  19. An On-Chip Nano-Plasmonics Based Urine Protein Assay Cartridge Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Long-term exposure to microgravity and radiation during space exploration can pose a critical threat to the health of a flight crew. Real-time monitoring of urine...

  20. 76 FR 41822 - In the Matter of Certain Toner Cartridges and Components Thereof; Notice of Commission...

    Science.gov (United States)

    2011-07-15

    ... San Antonia, Texas; Ink Technologies Printer Supplied, LLC (d/b/a/Ink Technologies LLC) of Dayton... complaint filed by Lexmark ] International, Inc. of Lexington, Kentucky (``Lexmark''). 75 FR. 62564- 65 (Oct.... 23-24) finding the remaining respondents in default. Commission Notice (Mar. 23, 2011) (Order No....

  1. 75 FR 62564 - In the Matter of: Certain Toner Cartridges and Components Thereof; Notice of Investigation

    Science.gov (United States)

    2010-10-12

    .... Ink Technologies Printer Supplies, LLC, (d/b/a Ink Technologies LLC), 7600 McEwen Road, Dayton, OH... Superstore), 1880 Century Park East, 200, Los Angeles, CA 90067. Chung Pal Shin (d/b/a Ink Master),...

  2. A pseudobiospecific hollow fiber cartridge for in vitro adsorption of autoantibodies from pathological serum

    Directory of Open Access Journals (Sweden)

    Ventura R.C.A.

    2000-01-01

    Full Text Available The affinity filtration technique using histidine as a pseudobiospecific ligand immobilized on poly(ethylene vinyl alcohol hollow fiber membranes (His-PEVA was used to remove autoantibodies from serum of patients with autoimmune disease. The effects of buffering solution conditions on the efficiency of autoantibodies removal was studied. The removal of anti-dsDNA, anti-SS-A/Ro, anti-Sm, anti-Sm/RNP and anti-cardiolipin autoantibodies present in the serum was investigated, comparing the efficiency between Hepes and Tris-HCl buffers. The results showed the potential of the membrane to remove all the autoantibodies studied. Anti SS-A/Ro was removed more efficiently in Tris-HCl buffer system rather than with the Hepes buffer.

  3. Chromatographic Separations Using Solid-Phase Extraction Cartridges: Separation of Wine Phenolics

    Science.gov (United States)

    Brenneman, Charles A.; Ebeler, Susan E.

    1999-12-01

    We describe a simple laboratory experiment that demonstrates the principles of chromatographic separation using solid-phase extraction columns and red wine. By adjusting pH and mobile phase composition, the wine is separated into three fractions of differing polarity. The content of each fraction can be monitored by UV-vis spectroscopy. When the experiment is combined with experiments involving HPLC or GC separations, students gain a greater appreciation for and understanding of the highly automated instrumental systems currently available. In addition, they learn about the chemistry of polyphenolic compounds, which are present in many foods and beverages and which are receiving much attention for their potentially beneficial health effects.

  4. Radiation characterization, and exposure rate measurements from cartridge, 105-mm, APFSDS-T, XM774

    Energy Technology Data Exchange (ETDEWEB)

    Bartlett, W.T.; Gilchrist, R.L.; Endres, G.W.R.; Baer, J.L.

    1979-11-01

    In response to a recommendation from the Joint Technical Coordinating Group for Munitions Effectiveness, Working Group on Depleted Uranium Munitions, the Department of the Army contracted with Pacific Northwest Laboratory (PNL) to investigate the health physics problems associated with the assembly, storage, and use of 105-mm, APFSDS-T, XM774 ammunition. Each round of this ammunition contains a penetrator rod of 3.4 kg of depleted uranium (DU), which is classified as a radioactive source material. The study carried out by PNL included laboratory and field analyses and an assessment of current health physics practices. The data sought included: the characteristics of radiation emitted from a penetrator and an assembled projectile; a comparison of film and thermoluminescent dosimeters; a comparison of radiation detection instruments; and the exposure rates from a single XM774 round, a loaded storage container, a standard pallet, and a loaded tank.

  5. Screening of Peptide Libraries Against Protective Antigen of Bacillus Anthracis in a Disposable Microfluidic Cartridge

    Science.gov (United States)

    2011-11-28

    Andre de Fusco, H. Tom Soh, Nancy E. Stagliano University of California - Santa Barbara The Regents of the University of California, Santa Barbara...Paul Pagano2, Dimitra N. Stratis-Cullum1*, David Chang-Yen2, Marek Turewicz2, Paul M. Pellegrino1, Andre de Fusco2, H. Tom Soh4, Nancy E. Stagliano3 1...U S A 98: 3750–3755. 4. Bupp K, Roth MJ (2002) Altering retroviral tropism using a random-display envelope library. Mol Ther 5: 329–335. 5. Muller OJ

  6. Indicator strip and portable instrument technologies for determining nitroesters or moisture in combustible cartridge cases

    Energy Technology Data Exchange (ETDEWEB)

    Griest, W.H.; Ho, C.H.; Moneyhun, J.H.; Agouridis, D.C.; Gayle, T.M.; Bates, B.E.

    1993-10-01

    The sometimes large round-to-round variability observed in accelerated environmental testing, plus difficulties in quantifying the environmental histories of a given round suggest the need for nondestructive rapid tests of munitions to supplement lifetime prediction models in quality assurance of munitions. Technologies are being developed for reagent strips which can be affixed to rounds and which will visually indicate the presence and extent of nitroester migration by a visible color change. A solid state adaptation of a modified Griess reagent develops a red-purple color in the presence of nitroesters. Performance of current designs tested in the laboratory suggest a short-term (ca. one month) single usage. Dielectric capacitance is a promising means for rapid, nondestructive moisture determinations using a portable battery-powered instrument. Laboratory studies with a modified, inexpensive, commercial device have demonstrated fast (a few seconds) detection of case wall moisture content.

  7. Spectrofluorimetric determination of formaldehyde in air after collection onto silica cartridges coated with Fluoral P

    OpenAIRE

    Pinheiro, Heloísa Lúcia C.; de Andrade, Marta Valéria Almeida Santana; Pereira, Pedro Afonso de Paula; Andrade,Jailson Bittencourt de

    2004-01-01

    p. 15-20 In the present work, a sensitive and selective fluorimetric method for formaldehyde determination in air samples is described. The method is based in the reaction between formaldehyde and Fluoral P producing 3,5-diacetyl-1,4-dihydrolutidine, which, when excited at 410 nm,emits fluorescence at 510 nm.The Fluoral P was prepared by the reaction of 0.3 ml of acetic acid, 0.2 ml of acetylacetone and 15.4 g of ammonium acetate. Then, the volume was completed to 100 ml with deionized wat...

  8. Determination of decamethylcyclopentasiloxane in air using commercial solid phase extraction cartridges.

    Science.gov (United States)

    Kierkegaard, Amelie; McLachlan, Michael S

    2010-05-21

    Decamethylcyclopentasiloxane (D(5)), a high production volume chemical used in personal care products, has been designated for regulation in Canada and is under review in the EU because of concerns about its persistence and potential for bioaccumulation in the environment. D(5) is a volatile compound expected to be found primarily in air, but there is little information on atmospheric concentrations due to the lack of sensitive analytical methods. Here a simple and sensitive method to determine D(5) in ambient air is presented. The challenge in the environmental analysis of D(5) is avoiding contamination. Our method is based on the high trapping efficiency of the sorbent Isolute ENV+, combined with a comparably high sampling rate. A small amount of sorbent (10 mg) is eluted in a small volume of n-hexane (0.1-0.6 mL), which is injected onto a GC/MS system without further processing. The simplicity of the method enables the use of a field blank for every sample to trace contamination. The method provides low limits of quantification (approximately 0.3 ng/m(3)), good repeatability and limited breakthrough (approximately 1%). By lowering the limit of quantification compared to published work by almost two orders of magnitude, it became possible to quantify D(5) in ambient air at locations remote from strong point sources. The concentrations at a rural Swedish site ranged from 0.7 to 8 ng/m(3) over a period of 4 months.

  9. Investigating the Retention Mechanisms of Liquid Chromatography Using Solid-Phase Extraction Cartridges

    Science.gov (United States)

    O'Donnell, Mary E.; Musial, Beata A.; Bretz, Stacey Lowery; Danielson, Neil D.; Ca, Diep

    2009-01-01

    Liquid chromatography (LC) experiments for the undergraduate analytical laboratory course often illustrate the application of reversed-phase LC to solve a separation problem, but rarely compare LC retention mechanisms. In addition, a high-performance liquid chromatography instrument may be beyond what some small colleges can purchase. Solid-phase…

  10. A study of the behaviour of irradiated or unirradiated grafts in the camera aquosa of irradiated and unirradiated animals; Etude du comportement d'un greffon irradie ou non, transplante dans la chambre anterieure de l'oeil d'un animal irradie ou non

    Energy Technology Data Exchange (ETDEWEB)

    Djalali-Behzad, G. [Commissariat a l' Energie Atomique, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

    1969-06-01

    Following grafts of new born mice spinal ganglia in the 'camera aquosa' of adult mice, the authors tried hematopoietic tissue grafts in the same conditions. The growth of iso-logous and hetero-logous bone marrow in the 'camera aquosa' showed that this tissue, even after exposure to supralethal doses, was capable of survival and growth. A counter-experiment with non irradiated bone marrow grafts in the 'camera aquosa' of rats delivered 700 rads led to the conclusion that the environment, intoxicated by exposure, acted on the graft so that after vascularization it became unable to grow. (author) [French] Apres avoir greffe des ganglions rachidiens de souriceaux nouveaux-nes dans la chambre anterieure de l'oeil de souris adultes, l'auteur a tente de greffer du tissu hematopoietique de la meme facon. La proliferation de la moelle osseuse isologue et heterologue, dans la chambre anterieure de l'oeil, lui a permis de mettre en evidence une certaine capacite de survie et de proliferation de ce tissu irradie meme a dose supraletale. Par une contre-experimentation, c'est-a-dire par la greffe de moelle non irradiee dans la chambre anterieure de rats irradies a 700 rads, il conclut que le milieu ambiant, intoxique par l'irradiation, agit sur le greffon de telle sorte que ce dernier, apres s'etre vascularise, devient depourvu de son aptitude de proliferation. (auteur)

  11. Specification for the Performance, Design, Development and Test Requirements for a Severe Environment Cartridge Recorder. Issue 4.

    Science.gov (United States)

    2014-09-26

    Interference Characteristics, Measurement of MIL-STD-810C Environmental Test Methods 2.5 Other American Ornanisations IRIG 118-73 Test Methods for Telemetry...Section 3-32(g) of IRIG 118-73. The measured output shall be less than 3.0% RMS at all controlled speeds. 5.2.4 Control The motor speed switch shall...Delay The technique of 5.2.2 shall be used to monitor motor speed while the output from the frequency discriminator of Section 3-32(g) of IRIG 118-73

  12. 76 FR 28457 - In the Matter of Certain Toner Cartridges and Components Thereof; Determination Not To Review an...

    Science.gov (United States)

    2011-05-17

    ... , Inc. of Reno, Nevada; XSE Group, Inc., d/b/a Image Star of Middletown, Connecticut; Copy Technologies..., 2010. 75 FR 44988 (July 30, 2010). The complaint alleged violations of section 337 of the Tariff Act of... named as respondents Ninestar Image Int'l, Ltd. of Zhuhai, China; Ninestar Technology Co., Ltd....

  13. Influence of Berdan and Boxer Primer Spit-Hole Diameter on 7.62-mm Cartridge Performance

    Science.gov (United States)

    2014-06-01

    barrel and breech. *Kapton is a registered trademark of E.I. du Pont de Nemours and Company...Zoomed-in force data for enlarged spit-hole. The data indicates alterations to the M80’s spit-hole area and configuration does not affect performance

  14. Design of a micro-cartridge system for the robotic assembly of exchangeable AFM-probe tips

    DEFF Research Database (Denmark)

    Bartenwerfer, Malte; Eichhorn, Volkmar; Fatikow, Sergej

    2013-01-01

    Modern processes of micro- and nanofabrication imply several metrology steps on critical dimensions in order to assure and assess device perfomences. Particularly, manufacturing processes of novel disruptive photonic devices and nanoelectronic circuit architectures require improved three dimensio......Modern processes of micro- and nanofabrication imply several metrology steps on critical dimensions in order to assure and assess device perfomences. Particularly, manufacturing processes of novel disruptive photonic devices and nanoelectronic circuit architectures require improved three...... dimensional acquisition and visualization techniques for their metrology. Amongst others line width and sidewall roughness are the most important parameters for nanooptical components but the determination of these parameters becomes increasingly demanding, since the continuous shrinkage of these devices...... demand an even higher lateral resolution of the measurements. The atomic force microscope (AFM) is a common tool for this characterization and a standard instrument for all kinds of research and development disciplines. However, the characterization of three dimensional high-aspect ratio and sidewall...

  15. 76 FR 60871 - In the Matter of Certain Toner Cartridges and Components Thereof; Notice of Commission Final...

    Science.gov (United States)

    2011-09-30

    ... Monte, California (``Alpha Image''); ACM Technologies, Inc. of Corona, California (``ACM''); Virtual... directed to defaulting domestic respondents E- Toner, Alpha Image, Copy Tech, LTT, C&R, ACM, Ink...

  16. Phu My's Environmental Protective Strategy of Toner Cartridge%富美硒鼓的环保战略

    Institute of Scientific and Technical Information of China (English)

    朱云龙

    2009-01-01

    @@ 富美科技有限公司是一家专业生产激光打印机硒鼓的高科技企业,其硒鼓产品已进入14个省市自治区的政府采购市场.我们知道,由于办公耗材具有严重的潜在环境危害性,政府在采购耗材时有着严格的环保要求,那么,富美科技又是如何做好环保工作的呢?

  17. First experiences with 2D-mXRF analysis of gunshot residue on garment, tissue, and cartridge cases

    Science.gov (United States)

    Knijnenberg, Alwin; Stamouli, Amalia; Janssen, Martin

    2014-09-01

    The investigation of garment and human tissue originating from a victim of a shooting incident can provide crucial information for the reconstruction of such an incident. The use of 2D-mXRF for such investigations has several advantages over current methods as this new technique can be used to scan large areas, provides simultaneous information on multiple elements, can be applied under ambient conditions and is non-destructive. In this paper we report our experiences and challenges with the implementation of 2D-mXRF in GSR analysis. Currently we mainly focus on the use of 2D-mXRF as a tool for visualizing elemental distributions on various samples.

  18. Study of cartridge rupture detection installations; Contribution a l'etude des installations de detection de ruptures de gaine

    Energy Technology Data Exchange (ETDEWEB)

    Graftieaux, J.; Douet, P.; Roguin, A. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1967-07-01

    Very numerous physical or technological parameters are involved in the preparation of projects for can rupture detection installations. These parameters are connected essentially with the design of the reactor, the detector used, the disposition of the pneumatic circuits, the type of fuel and the safety required. The present report analyses the main problems arising and their mutual compatibilities; it defines a certain number of ideas which had up till now been accepted implicitly in the design. (authors) [French] De tres nombreux parametres physiques ou technologiques interviennent dans l'etablissement du projet d'une installation de detection de ruptures de gaines. Ces parametres decoulent essentiellement de la conception de la pile, du detecteur utilise, de l'organisation des circuits pneumatiques, du type du combustible et de la securite souhaitee. Le present document analyse les principaux problemes qui se posent ainsi que leurs compatibilites reciproques et precise un certain nombre de notions jusqu'alors admises implicitement lors de l'etablissement des projets. (auteurs)

  19. Should the U.S. Army Adopt New 5.56mm Ammunition Cartridge Designs to Reduce Overall Ammunition Weight?

    Science.gov (United States)

    2011-06-10

    and D. H. J. Halsey. Ammunition (Including Grenades and Mines . Shrivenham, UK: Brassey’s Publishers, 1982). McLaughlin Green, Constance , Harry...http://hsrlab.gatech.edu/AUTODYN/ papers/paper162.pdf (accessed 18 January 2011). McLaughlin Green, Constance , Harry C. Thomson, and Peter C. Root

  20. Proteoglycan from salmon nasal cartridge [corrected] promotes in vitro wound healing of fibroblast monolayers via the CD44 receptor.

    Science.gov (United States)

    Ito, Gen; Kobayashi, Takeshi; Takeda, Yoshie; Sokabe, Masahiro

    2015-01-16

    Proteoglycans (PGs) are involved in various cellular functions including cell growth, adhesion, and differentiation; however, their physiological roles are not fully understood. In this study, we examined the effect of PG purified from salmon nasal cartilage (SNC-PG) on wound closure using tissue-cultured cell monolayers, an in vitro wound-healing assay. The results indicated that SNC-PG significantly promoted wound closure in NIH/3T3 cell monolayers by stimulating both cell proliferation and cell migration. SNC-PG was effective in concentrations from 0.1 to 10μg/ml, but showed much less effect at higher concentrations (100-1000μg/ml). The effect of SNC-PG was abolished by chondroitinase ABC, indicating that chondroitin sulfates (CSs), a major component of glycosaminoglycans (GAGs) in SNC-PG, are crucial for the SNC-PG effect. Furthermore, chondroitin 6-sulfate (C-6-S), a major CS of SNC-PG GAGs, could partially reproduce the SNC-PG effect and partially inhibit the binding of SNC-PG to cells, suggesting that SNC-PG exerts its effect through an interaction between the GAGs in SNC-PG and the cell surface. Neutralization by anti-CD44 antibodies or CD44 knockdown abolished SNC-PG binding to the cells and the SNC-PG effect on wound closure. These results suggest that interactions between CS-rich GAG-chains of SNC-PG and CD44 on the cell surface are responsible for the SNC-PG effect on wound closure.

  1. Development of a reflectron time-of-flight mass spectrometer for non-destructive analysis of isotope ratios in irradiated B4C pellets--Test measurements on an unirradiated control rod pellet

    Science.gov (United States)

    Manoravi, P.; Joseph, M.; Sivakumar, N.

    2008-09-01

    A laser mass spectrometric facility is developed using a home-built reflectron time-of-flight mass spectrometer (RTOFMS) to analyze the boron isotopic ratio 10B/11B in the irradiated B4C pellets of the FBTR control rod. Compared to other mass spectrometry-based methods, the present method is practically non-destructive and makes it relatively easier to handle irradiated (radioactive) B4C pellets through remote operation. The results with inactive samples indicate that the method yields 10B percentage values, accurate to within ±1%.

  2. Nanjing Yunsu Launched the Portable Toner Cartridge Refilling Machine%南京云苏推出便携式加粉机

    Institute of Scientific and Technical Information of China (English)

    成星

    2010-01-01

    @@ 最近,南京云苏科技推出了一款便携式硒鼓加粉机,把人们"提着机器到客户门上加粉去"的愿望变成了现实. 这款机型利用云苏科技YSA型加粉机德专利技术,在保留A型机"不拆开硒鼓,真空抽除残粉、废粉,封闭加入新粉,加粉过程墨粉不飞扬,不损害操作人员肺部健康"等优点得同时,还具有以下三个特点:

  3. Phu My Toner Cartridge Developed Fully on the Domestic Market%富美硒鼓全面拓展国内市场

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    @@ 中国的耗材产业要做大做强,就必须走规模化、产业化自主创新之路,富美科技在启动之初,制定了科学而明确的市场战略"同台高端、鲜明区隔",主打高端市场.

  4. 废弃硒鼓残留墨粉的爆炸参数研究%Study on Toner Dust Explosion Characteristic of Waste Toner Cartridge

    Institute of Scientific and Technical Information of China (English)

    李秀丽; 王景伟

    2012-01-01

    为研究废弃硒鼓中残留墨粉的爆炸特性,对hpQ2612A型墨粉的物化性质进行了分析,并实验测试其爆炸参数,判断墨粉的爆炸敏感性和强度,从而指导硒鼓资源化工艺设计中的爆炸预防和防护措施.结果表明:墨粉粉尘具有爆炸性,其爆炸压力中等,爆炸指数较大,爆炸下限较低;墨粉粉尘层不易发生自燃,在250℃时熔化,高于400℃时不着火;墨粉粉尘云着火温度较高,但粉尘云最小点火能量较低.说明墨粉爆炸敏感度较高,爆炸猛烈度也较大.

  5. Preconcentration sensitive determination of pyrethroid insecticides in environmental water samples with solid phase extraction with SiO2 microspheres cartridge prior to high performance liquid chromatography.

    Science.gov (United States)

    Zhou, Qingxiang; Gao, Yuanyuan; Bai, Huahua; Xie, Guohong

    2010-07-30

    Present study developed a new method for the sensitive determination of pyrethroid insecticides with solid phase extraction in combination with high performance liquid chromatography and UV detector. SiO(2) microspheres, a new SiO(2) based material, was investigated for the enrichment ability and applicability as the solid phase extraction sorbent. Four pyrethroid pesticides such as fenpropathrin, cyhalothrin, fenvalevate and biphenthrin were used as the target analytes. Parameters that maybe influence the extraction efficiency such as the eluent type and its volume, sample flow rate, sample pH, and the sample volume were optimized in detail, and the optimal conditions were as followed: sample volume, 100mL; concentration of methanol, 30%; acetone volume, 5mL; sample flow rate, 4.2mLmin(-1); sample pH, 7. The experimental results indicated that there was good linearity in the concentration range of 0.1-50microgL(-1) except biphenthrin in the range of 0.05-25microgL(-1). The detection limits for fenpropathrin, cyhalothrin, fenvalevate and biphenthrin were in the range of 0.02-0.08microgL(-1). The intra-day and day to day precisions (RSDs, n=6) were in the ranges of 2.6-4.4% and 5.3-7.2%, respectively. The method was validated with five real environmental water samples, and all these results proved that proposed method could be used as a good alternative for the routine analysis for such pollutants in environmental samples.

  6. Automated Sample Preparation (ASP): Development of a Rapid Method to Sequentially Isolate Nucleic Acids and Protein from Any Sample Type by a Cartridge-Based System

    Science.gov (United States)

    2013-11-27

    SECURITY CLASSIFICATION OF: CUBRC has developed an in-line, multi-analyte isolation technology that utilizes solid phase extraction chemistries to purify...demonstrated the field deployability of the handheld version of this technology by isolating nucleic acid and protein from Yersinia pestis (avirulent

  7. Installation and Commissioning of RCP Cartridge for Nuclear Power Stations%核电厂主泵密封系统的安装与调试

    Institute of Scientific and Technical Information of China (English)

    霍亚邦; 王玉旭

    2011-01-01

    The installation process and method for the cooling pump sealing system of CPR1000 nuclear power plant reactor is studied, and various cases occurred during the installation and commisioning of RCP sealing systems are analyzed. The scheme for flushing of the nuclear loop in the various cases is developed to provide a reference for the installation and commissioning of RCP sealing system in the coming CPR1000 project.%研究CPR1000堆型核电厂反应堆冷却剂泵(RCP)密封安装工艺流程及方法,对RCP密封系统安装和调试过程中的各种情况进行分析,制定各种情况下核回路冲洗采取的特殊处理方案,为后续CPR1000项目RCP密封系统安装调试提供参考.

  8. Heat Transfer Analysis of an Optimized, Flexible Holder System for Freeze-Drying in Dual Chamber Cartridges Using Different State-of-the-Art PAT Tools.

    Science.gov (United States)

    Korpus, Christoph; Pikal, Michael; Friess, Wolfgang

    2016-11-01

    The aim of this study was to determine the heat transfer characteristics of an optimized flexible holder device, using Tunable Diode Laser Absorption Spectroscopy, the Pressure Rise Test, and the gravimetric procedure. Two different controlled nucleation methods were tested, and an improved sublimation process, "preheated plate," was developed. Tunable Diode Laser Absorption Spectroscopy identified an initial sublimation burst phase. Accordingly, steady-state equations were adapted for the gravimetric procedure, to account for this initial non-steady-state period. The heat transfer coefficient, KDCC, describing the transfer from the holder to the DCC, was the only heat transfer coefficient showing a clear pressure dependence with values ranging from 3.81E-04 cal/(g·cm(2)·K) at 40 mTorr to 7.38E-04 cal/(g·cm(2)·K) at 200 mTorr. The heat transfer coefficient, Ktot, reflecting the overall energy transfer via the holder, increased by around 24% from 40 to 200 mTorr. This resulted in a pressure-independent sublimation rate of around 42 ± 1.06 mg/h over the whole pressure range. Hence, this pressure-dependent increase in energy transfer completely compensated the decrease in driving force of sublimation. The "flexible holder" shows a substantially reduced impact of atypical radiation, improved drying homogeneity, and ultimately a better transferability of the freeze-drying cycle for process optimization.

  9. Clinical evaluation of high-risk HPV detection on self-samples using the indicating FTA-elute solid-carrier cartridge

    NARCIS (Netherlands)

    Geraets, D.T.; Baars, R. van; Alonso, I.; Ordi, J.; Torne, A.; Melchers, W.J.G.; Meijer, C.J.W.; Quint, W.G.V.

    2013-01-01

    BACKGROUND: High-risk human papillomavirus (hrHPV) testing in cervical screening is usually performed on physician-taken cervical smears in liquid-based medium. However, solid-state specimen carriers allow easy, non-hazardous storage and transportation and might be suitable for self-collection by

  10. Exploitation of FTA cartridges for the sampling, long-term storage, and DNA-based analyses of plant-parasitic nematodes.

    Science.gov (United States)

    Marek, Martin; Zouhar, Miloslav; Douda, Ondřej; Maňasová, Marie; Ryšánek, Pavel

    2014-03-01

    The use of DNA-based analyses in molecular plant nematology research has dramatically increased over recent decades. Therefore, the development and adaptation of simple, robust, and cost-effective DNA purification procedures are required to address these contemporary challenges. The solid-phase-based approach developed by Flinders Technology Associates (FTA) has been shown to be a powerful technology for the preparation of DNA from different biological materials, including blood, saliva, plant tissues, and various human and plant microbial pathogens. In this work, we demonstrate, for the first time, that this FTA-based technology is a valuable, low-cost, and time-saving approach for the sampling, long-term archiving, and molecular analysis of plant-parasitic nematodes. Despite the complex structure and anatomical organization of the multicellular bodies of nematodes, we report the successful and reliable DNA-based analysis of nematode high-copy and low-copy genes using the FTA technology. This was achieved by applying nematodes to the FTA cards either in the form of a suspension of individuals, as intact or pestle-crushed nematodes, or by the direct mechanical printing of nematode-infested plant tissues. We further demonstrate that the FTA method is also suitable for the so-called "one-nematode-assay", in which the target DNA is typically analyzed from a single individual nematode. More surprisingly, a time-course experiment showed that nematode DNA can be detected specifically in the FTA-captured samples many years after initial sampling occurs. Collectively, our data clearly demonstrate the applicability and the robustness of this FTA-based approach for molecular research and diagnostics concerning phytonematodes; this research includes economically important species such as the stem nematode (Ditylenchus dipsaci), the sugar beet nematode (Heterodera schachtii), and the Northern root-knot nematode (Meloidogyne hapla).

  11. Integration of Sensor Technologies into Respirator Vapor Cartridges as End-of-Service-Life Indicators: Literature and Manufacturer’s Review and Research Roadmap

    Science.gov (United States)

    2005-05-06

    energy from micro- 25 solar cells , (3) high surface area, nanostructured aerogels for higher energy storage capacity, and (4) new nanostructured... interdigital microelectrode. The sensor operates by absorbing vapors into the organic monolayer, which causes a large modulation in the electrical...single-wall carbon nanotubes on an interdigitated electrode. The sensor responses were linear for concentrations of sub ppm to hundreds of ppm with

  12. The Analysis of Launch Safety of Ignition Cartridge of Mortar Bomb at Low Temperature%迫击炮弹基本药管低温发射安全性分析

    Institute of Scientific and Technical Information of China (English)

    邱从礼; 侯日升

    2012-01-01

    研究了某型迫击炮弹基本药管发射安全性的评估方法.分析了迫击炮弹尾管炸裂原因,建立了一种预测迫击炮弹尾管炸裂发生概率的方法,通过统计推断出其低温最大尾管压服从正态分布,计算了尾管炸裂概率.结果表明该迫击炮弹尾管炸裂概率较大,通过改进基本药管,消除了尾管炸裂隐患.建立的尾管炸裂概率预测方法可用于迫击炮弹基本药管的发射安全性分析.

  13. "易加粉"环保硒鼓成为外博会亮点%"Toner Loading Easily" the Environmental Protective Cartridge Become a Bright Spot in Foreign Expo

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    @@ 2009年6月18日到20日,首届广东外商投资企业产品内销博览会在东莞广东现代国际展览中心举行.珠海市外经贸局带领珠海多家企业参展,受到众多行业用户单位和参观者好评.

  14. Experimental study on cleaning process of large-flow pleated fabric cartridge filters during pulse-jet cleaning%脉冲喷吹大风量滤筒除尘器的清灰变化过程研究

    Institute of Scientific and Technical Information of China (English)

    颜翠平; 张明星; 吕娟; 王岩; 李倩倩

    2016-01-01

    褶皱比高、过滤面积大的大风量滤筒除尘器存在不完全清灰的随机性更大,因为脉冲清灰过程中脉冲气流在滤筒内的流场分布不均引起滤简侧壁压力的不均匀分布.主要通过检验大风量滤筒(φ325×1 000 mm)侧壁压力峰值变化过程和探寻引起侧壁压力峰值分布的气流动态变化过程.实验结果表明,冷态实验时,有诱导喷嘴时,滤筒侧壁压力峰值呈现从上到下减小的趋势,滤筒侧壁压力变化过程与滤筒上粉尘剥落的过程相一致;动态实验时,随着过滤风速增大,滤筒侧壁压力峰值出现增大的现象,因为脉冲气流受到系统过滤气流的影响,脉冲气流在轴向的速度降低的要缓慢一些,动压转化为静压的速度要缓慢一些,出现滤筒650 mm位置侧壁压力峰值明显增大,而在滤筒850 mm位置侧壁压力峰值并未增大,将动态实验用于实际现场,结果表明,长时间运行滤筒底部出现清灰效果差的现象.

  15. Two-gun suicide by simultaneous shots to the head: interdisciplinary reconstruction on the basis of scene investigation, autopsy findings, GSR analysis and examination of firearms, bullets and cartridge cases.

    Science.gov (United States)

    Grosse Perdekamp, Markus; Nadjem, Hadi; Merkel, Joachim; Braunwarth, Roland; Pollak, Stefan; Thierauf, Annette

    2011-07-01

    Suicidal shots fired simultaneously to the head from two handguns are rare. The authors report about a recent case in which a Smith & Wesson cal. 9 mm pistol and a Smith & Wesson cal. .357 Magnum revolver were used. Sitting on a sofa, a 33-year-old man (member of a shooting club) fired two simultaneous shots to the head; the pistol held in the left hand was discharged into the left temple, and the revolver held in the right hand was fired into the mouth. Both weapons remained in the respective hands. An upside-down muzzle imprint in the left temporal region and recoil injuries of a mandibular incisor, and the lower lip indicated that both the pistol and the revolver had been held in an inverted manner at the time of discharge. Blood stains (backspatter) and gunshot residues were present on both firing hands, whereas forward spatter originating from the exit wounds was deposited on the wall behind the suicide's head.

  16. Development of methodology for characterization of cartridge filters from the IEA-R1 using the Monte Carlo method; Desenvolvimento de uma metodologia para caracterizacao do filtro cuno do reator IEA-R1 utilizando o Metodo Monte Carlo

    Energy Technology Data Exchange (ETDEWEB)

    Costa, Priscila

    2014-07-01

    The Cuno filter is part of the water processing circuit of the IEA-R1 reactor and, when saturated, it is replaced and becomes a radioactive waste, which must be managed. In this work, the primary characterization of the Cuno filter of the IEA-R1 nuclear reactor at IPEN was carried out using gamma spectrometry associated with the Monte Carlo method. The gamma spectrometry was performed using a hyperpure germanium detector (HPGe). The germanium crystal represents the detection active volume of the HPGe detector, which has a region called dead layer or inactive layer. It has been reported in the literature a difference between the theoretical and experimental values when obtaining the efficiency curve of these detectors. In this study we used the MCNP-4C code to obtain the detector calibration efficiency for the geometry of the Cuno filter, and the influence of the dead layer and the effect of sum in cascade at the HPGe detector were studied. The correction of the dead layer values were made by varying the thickness and the radius of the germanium crystal. The detector has 75.83 cm{sup 3} of active volume of detection, according to information provided by the manufacturer. Nevertheless, the results showed that the actual value of active volume is less than the one specified, where the dead layer represents 16% of the total volume of the crystal. A Cuno filter analysis by gamma spectrometry has enabled identifying energy peaks. Using these peaks, three radionuclides were identified in the filter: {sup 108m}Ag, {sup 110m}Ag and {sup 60}Co. From the calibration efficiency obtained by the Monte Carlo method, the value of activity estimated for these radionuclides is in the order of MBq. (author)

  17. 广东省质监局发布地方标准《喷墨打印机墨盒通用技术规范》%《General Technical Specifications for Ink Cartridge of Inkjet Printers》

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ 广东省质监局正式批准发布了广东省地方标准,结束了喷墨打印机墨盒(以下简称墨盒)长期以来无地方及行业(包括国家)的技术标准来指导生产、规范市场的局面.

  18. Suggestions for Preparing "General specification for cartridge - spare part of Ink-Jet printer"%《喷墨打印机的零配件--喷墨盒的通用规范》制定建议

    Institute of Scientific and Technical Information of China (English)

    潘小平

    2004-01-01

    依据正在制定中的电子行业标准对墨盒性能指标测试.针对测试过程中发现的问题,并结合当前墨盒技术的发展趋势,建议增加墨盒残余量、色差、色彩再现能力等技术指标.同时根据测试经验,对标准中耐光性、耐水性、打印寿命等指标的测试方法提出了改进意见.

  19. [Experimental effect of a shot caused by 4.5 mm cartridges fired from a Norica Dragon air-rifle and a Walther PPK/S air-pistol].

    Science.gov (United States)

    Smedra-Kaźmirska, Anna; Barzdo, Maciej; Kedzierski, Maciej; Szram, Stefan; Berent, Jarosław

    2010-01-01

    In Poland, according to the Weapons and Ammunition Act" an air weapon which has kinetic energy of fired projectiles below 17 J does not require registration and can be bought even on the Internet. Sport and recreational shooting with this weapon does not have to be performed in a special shooting-range, but can be carried on in an open terrain providing "particular caution" is exercised. In this study we presented experimental effects of shooting pneumatic weapons (Norica Dragon air-rifle and Walther PPK/S air-pistol) which had kinetic energy of fired projectiles below 17 J. The aim of this study was to assess the effects of shooting the above weapons at human soft tissues and thin bones of the temple region to empirically evaluate the degree of danger to health and life, which such shots can produce. We used 20% gelatine blocks at 10 degrees C, which were the model of human soft tissues, and fresh calf scapulas, which served as the models of the temporal bone of the human cranium. Before the experiment, we had evaluated the weight of all the projectiles and their initial velocity using a chronograph. By these measures, we calculated the kinetic energy of the fired missiles. After shooting, we estimated if projectiles of different shapes shot from air weapons characterized by different kinetic energy and from different distances penetrated the gelatine blocks and if the said missiles perforated the bones. We also measured the depth of missiles penetration in the gelatine blocks.

  20. Topical Hazard Evaluation Program of Candidate Insect Repellent AI3-30180-c, US Department of Agriculture Proprietary Chemical, April 1982 - September 1984.

    Science.gov (United States)

    1985-01-10

    irritation photochemical chemical and 10 percent reaction under test con- irritation in humans. (wlv) Oil of Bergamot ditions. 2 * - Study No. 75-51-0367-85...control (oil of Bergamot ), than unirradiated skin areas. a and diluent were applied to additional skin areas to serve as unirradiated control sites

  1. Influence of gamma radiation on the colour strength and fastness properties of fabric using turmeric (Curcuma longa L.) as natural dye

    Energy Technology Data Exchange (ETDEWEB)

    Bhatti, Ijaz A., E-mail: ijazchem@yahoo.co [Department of Chemistry, University of Agriculture, Faisalabad 38040 (Pakistan); Adeel, Shahid [Department of Chemistry, University of Agriculture, Faisalabad 38040 (Pakistan); Jamal, M. Asghar [Department of Chemistry, G.C. University, Faisalabad 38040 (Pakistan); Safdar, Muhammad [Department of Chemistry, University of A J and K, Muzaffarabad, Azad Kashmir (Pakistan); Abbas, Muhammad [Haris Dyes and Chemicals, Faisalabad 38040 (Pakistan)

    2010-05-15

    The effect of gamma radiation on the dyeing of cotton with extract of turmeric (Curcuma longa L.) powder has been investigated. Cotton fabric and turmeric powder were irradiated to absorbed doses of 1, 2, 3, 4 and 6 kGy using Co-60 gamma irradiator. Dyeing parameters such as temperature, pH and mordant concentration were optimized. Dyeing was performed using un-irradiated and irradiated cotton with the extracts of un-irradiated and irradiated turmeric powder in order to investigate the effect of radiation treatment on the colour strength of dyed fabric. The reported data of un-irradiated and irradiated fabrics dyed with un-irradiated and irradiated dyes were obtained using the spectraflash SF-650. The colourfastness to light, rubbing- and washing-fastness properties showed that gamma irradiation has improved the dyeing characteristics from fair to good.

  2. Influence of gamma radiation on the colour strength and fastness properties of fabric using turmeric (Curcuma longa L .) as natural dye

    Science.gov (United States)

    Bhatti, Ijaz A.; Adeel, Shahid; Jamal, M. Asghar; Safdar, Muhammad; Abbas, Muhammad

    2010-05-01

    The effect of gamma radiation on the dyeing of cotton with extract of turmeric ( Curcuma longa L.) powder has been investigated. Cotton fabric and turmeric powder were irradiated to absorbed doses of 1, 2, 3, 4 and 6 kGy using Co-60 gamma irradiator. Dyeing parameters such as temperature, pH and mordant concentration were optimized. Dyeing was performed using un-irradiated and irradiated cotton with the extracts of un-irradiated and irradiated turmeric powder in order to investigate the effect of radiation treatment on the colour strength of dyed fabric. The reported data of un-irradiated and irradiated fabrics dyed with un-irradiated and irradiated dyes were obtained using the spectraflash SF-650. The colourfastness to light, rubbing- and washing-fastness properties showed that gamma irradiation has improved the dyeing characteristics from fair to good.

  3. Effects of neutron irradiation on microstructure and mechanical properties of pure iron

    DEFF Research Database (Denmark)

    Singh, B.N.; Horsewell, Andy; Toft, P.

    1999-01-01

    tensile tested at the irradiation temperatures. Microstructures of the as-irradiated and irradiated and tensile tested specimens were investigated by transmission electron microscopy. Fracture surfaces of tensile tested specimens in unirradiated and irradiated conditions were examined in a scanning...

  4. Effect of Radiation Exposure on the Retention of Commercial NAND Flash Memory

    Science.gov (United States)

    Oldham, Timothy R.; Chen, D.; Friendlich, M.; Carts, M. A.; Seidleck, C. M.; LaBel, K. A.

    2011-01-01

    We have compared the data retention of irradiated commercial NAND flash memories with that of unirradiated controls. Under some circumstanc es, radiation exposure has a significant effect on the retention of f lash memories.

  5. Study on the Structure and Feature of the Ignition Cartridge with Paper Case under the Condition of Tail Pressure of Propelling Charge of Mortar Bomb%迫弹发射装药高尾压下纸制基本药管结构特点探讨

    Institute of Scientific and Technical Information of China (English)

    孙华; 潘会平

    2010-01-01

    纸制基本药管是迫弹发射装药的常规结构,但是随着近几年迫击炮武器系统各方面性能的提升,附加装药的装填密度越来越大,为保证基本装药的点火能力及与附加装药的匹配性,尾管压力不断提高,于是带来了纸制基本药管的强度问题.文章首先介绍了纸制基本药管因尾管压力升高而出现的现象,分析了出现上述现象的原因,并探讨了应对措施和改进方法.

  6. 不同填料的固相小柱对替诺昔康血浆样本萃取回收率的研究%Study on the extraction recovery of tenoxicam in plasma by different solid-phase cartridges

    Institute of Scientific and Technical Information of China (English)

    高立勤

    2002-01-01

    目的以替诺昔康为研究对象,考察不同填料固相小柱的萃取效率,从而确定固相萃取替诺昔康血浆样本的实验方法.方法替诺昔康血浆样本经硅胶,C18,大孔网格树脂,酸性氧化铝和CHA-101树脂小柱萃取后,分别在ODS柱上,以甲醇-水-三乙胺(13∶87∶0.05)为流动相,进行高效液相色谱分析.通过比较不同填料的萃取回收率,选择最佳的固相填料.结果在所考察的5种固相填料中,大孔网格树脂的萃取回收率最高.结论经试验,大孔网格树脂的萃取回收率可达90%以上,适用于血浆中替诺昔康的分析.

  7. Thermally activated deformation of irradiated reactor pressure vessel steel

    Science.gov (United States)

    Böhmert, J.; Müller, G.

    2002-03-01

    Temperature and strain rate change tensile tests were performed on two VVER 1000-type reactor pressure vessel welds with different contents of nickel in unirradiated and irradiated conditions in order to determine the activation parameters of the contribution of the thermally activated deformation. There are no differences of the activation parameters in the unirradiated and the irradiated conditions as well as for the two different materials. This shows that irradiation hardening preferentially results from a friction hardening mechanism by long-range obstacles.

  8. Sterile insect technique and F₁ sterility in the European grapevine moth, Lobesia botrana.

    Science.gov (United States)

    Saour, George

    2014-01-23

    Newly emerged adults of the European grapevine moth, Lobesia botrana (Denis and Schiffermuller) (Lepidoptera: Tortricidae), were irradiated with various doses of gamma radiation and crossed to unirradiated counterparts of the opposite sex. Fecundity was decreased when unirradiated females were mated with either 300-or 350-Gy-irradiated males. Adult males that were irradiated with 400 Gy and mated with unirradiated females retained a residual fertility of 2.7%. The radiation dose at which irradiated females were found to be 100% sterile when mated with unirradiated males was 150 Gy. The inherited effects in the F1 progeny of irradiated male parents were examined at 100, 150, and 200 Gy. Fecundity and fertility of the F1 progeny of males irradiated with 150 Gy and inbred or crossed with irradiated and unirradiated moths were also recorded. A significant reduction in fertility was observed when F1 males mated with either F1 or unirradiated females. According to sterility index, F1 females who mated with F1 males had greater sterility than when F1 females were crossed to 150-Gy-irradiated males. Based upon the results of this study, 150 Gy of gamma radiation would be the optimal dose to use in a sterile insect technique and F1 sterility program against L. botrana.

  9. Sterile Insect Technique and F1 Sterility in the European Grapevine Moth, Lobesia botrana

    Science.gov (United States)

    Saour, George

    2014-01-01

    Newly emerged adults of the European grapevine moth, Lobesia botrana (Denis and Schiffermuller) (Lepidoptera: Tortricidae), were irradiated with various doses of gamma radiation and crossed to unirradiated counterparts of the opposite sex. Fecundity was decreased when unirradiated females were mated with either 300- or 350-Gy-irradiated males. Adult males that were irradiated with 400 Gy and mated with unirradiated females retained a residual fertility of 2.7%. The radiation dose at which irradiated females were found to be 100% sterile when mated with unirradiated males was 150 Gy. The inherited effects in the F1 progeny of irradiated male parents were examined at 100, 150, and 200 Gy. Fecundity and fertility of the F1 progeny of males irradiated with 150 Gy and inbred or crossed with irradiated and unirradiated moths were also recorded. A significant reduction in fertility was observed when F1 males mated with either F1 or unirradiated females. According to sterility index, F1 females who mated with F1 males had greater sterility than when F1 females were crossed to 150-Gy-irradiated males. Based upon the results of this study, 150 Gy of gamma radiation would be the optimal dose to use in a sterile insect technique and F1 sterility program against L. botrana. PMID:25373155

  10. Hypoxic Tumor Can be More Responsive to Fractionated Irradiation Combined with SR 4233 (Tirapazamine)

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Il Han [Seoul National University College of Medicine, Seoul (Korea, Republic of); Brown, J. Martin [Stanford Univ., Stanford (United States)

    1994-02-15

    Hypothesis that hypoxic tumors should be more responsive to the addition of preferential hypoxic cell cytotoxin SR 4233 (tirapazamine) to fractionated irradiation was tested in the mouse SCCVII carcinoma and RIF-1 sarcoma, Model of hypoxic tumor was established using the tumor bed effect; tumors growing in the preirradiated tissue (preirradiated tumors) were more hypoxic than tumors growing in the unirradiated tissue (unirradiated tumors). When the tumors reached a mean volume of 100 mm{sup 3}, both unirradiated and preirradiated tumors were treated with a fractionated course of 6 x 2 Gy in 3 days or 8 x2.5 Gy in 4 days with SR 4233 (0.08m mol/kg/injection) given 30 minutes before each irradiation or without SR 4233. Compared to the unirradiated tumors, hypoxic preirradiated tumors were approximately 5 times more resistant to fractionated irradiation alone but were approximately 5 times more responsive to SR 4233. Addition of SR 4233 potentiated the effect of fractionated irradiation in both unirradiated and preirradiated tumors. Potentiation in the preirradiated tumors was morequal to or greater than that in the unirradiated tumors and seemed to be higher for more fractionated treatment. We confirm the hypothesis in a transplantable mouse tumor. Present results suggest that radioresistance of some hypoxic tumors can be overcome with hypoxic cytotoxin.

  11. Explosive welding of a tube into a tube sheet

    Energy Technology Data Exchange (ETDEWEB)

    Green, Sheryll C. (London, OH); Linse, Vonne D. (Columbus, OH)

    1978-10-03

    A cartridge containing an explosive charge is placed within a tube assembled within a tube sheet. The charge is detonated through use of a detonator cord containing a minimum but effective amount of explosive material. The cord is contained inside a tubular shield throughout most of its length within the cartridge. A small length of the cord extends beyond the tubular shield to contact and detonate the explosive charge in its rear portion near the cartridge base. The cartridge base is provided of substantial mass and thickness in respect to side and front walls of the cartridge to minimize bulging beyond the rear face of the tube sheet. For remote activation an electrically activated detonator of higher charge density than the cord is attached to the cord at a location spaced from the tube sheet, cartridge and tube.

  12. Explosive welding of a tube into a tube sheet

    Energy Technology Data Exchange (ETDEWEB)

    Green, S.C.; Linse, V.D.

    1978-10-03

    A cartridge containing an explosive charge is placed within a tube assembled within a tube sheet. The charge is detonated through use of a detonator cord containing a minimum but effective amount of explosive material. The cord is contained inside a tubular shield throughout most of its length within the cartridge. A small length of the cord extends beyond the tublar shield to contact and detonate the explosive charge in its rear portion near the cartridge base. The cartridge base is provided of substantial mass and thickness in respect to side and front walls of the cartridge to minimize bulging beyond the rear face of the tube sheet. For remote activation an electrically activated detonator of higher charge density than the cord is attached to the cord at a location spaced from the tube sheet, cartridge and tube.

  13. Advantageous use of SSA technique to observe effects of thickness, antioxidant and oxygen in gamma irradiated low density polyethylene

    Energy Technology Data Exchange (ETDEWEB)

    Perez, C.J., E-mail: cjperez@fi.mdp.edu.ar [Research Institute of Material Science and Technology (INTEMA), National Research Council (CONICET), Engineering Faculty, Mar del Plata University, Av. J.B. Justo 4302, 7600 Mar del Plata (Argentina); Failla, M.D. [Planta Piloto de Ingenieria Quimica-PLAPIQUI (UNS-CONICET), Camino ' La Carrindanga' Km 7, 8000 Bahia Blanca (Argentina); Carella, J.M. [Research Institute of Material Science and Technology (INTEMA), National Research Council (CONICET), Engineering Faculty, Mar del Plata University, Av. J.B. Justo 4302, 7600 Mar del Plata (Argentina)

    2012-06-20

    Highlights: Black-Right-Pointing-Pointer Information from successive self-nucleation and annealing technique is analyzed. Black-Right-Pointing-Pointer Oxygen and antioxidants reduce crosslinking efficiency by reaction with free radicals. Black-Right-Pointing-Pointer Recognizable differences are obtained in samples irradiated at different atmospheres. - Abstract: Information obtained from successive self-nucleation and annealing (SSA) technique is analyzed, paying special attention to the observable effects of samples thickness and antioxidant and oxygen concentrations. Molecular structure changes for low density polyethylene (LDPE) samples, irradiated under three different atmospheres for doses between 33 and 222 kGy were analyzed, with emphasis on the changes of longer polymethylene crystallizable lengths. Antioxidant and oxygen concentrations were varied for samples of different thickness to study the effects on degradation. The changes in the molecular structure were followed simultaneously by SSA and Infrared spectroscopy (FTIR) via carbonyl group concentration. Preliminary quantifications of the SSA technique sensitivity are also advanced.

  14. Excavation of the Foote Site Dump (10-AA-96).

    Science.gov (United States)

    1982-01-01

    1 2 2 Nails - Total cut1 Wire Sheet Strap Plate I Suspender Kerosene Lamp Burner Cartridge 1 1 Shotgun shell 1 1 Safety pin Cord finial Chain Fitting...Lamp Burner Cartridge Shotgun shell Safety pin Cord finial Chain Fitting Screw Shoe hook Paper clip Token Miscellaneous White Metal - Total Strap...Nails - Total Cut Wire Sheet I Strap Plate Suspender Kerosene Lamp Burner Cartridge 1 Shotgun shell Safety pin 2 Cord finial Chain 2 Fitting Screw

  15. System for injecting fuel in a gas turbine combustor

    Science.gov (United States)

    Berry, Jonathan Dwight

    2016-10-25

    A combustion system uses a fuel nozzle with an inner wall having a fuel inlet in fluid communication with a fuel outlet in a fuel cartridge. The inner wall defines a mounting location for inserting the fuel cartridge. A pair of annular lip seals around the cartridge outer wall on both sides of the fuel outlet seals the fuel passage between the fuel inlet and the fuel outlet.

  16. Bystander apoptosis in human cells mediated by irradiated blood plasma

    Energy Technology Data Exchange (ETDEWEB)

    Vinnikov, Volodymyr, E-mail: vlad.vinnikov@mail.ru [Grigoriev Institute for Medical Radiology of the National Academy of Medical Science of Ukraine (Ukraine); Lloyd, David; Finnon, Paul [Centre for Radiation, Chemical and Environmental Hazards of the Health Protection Agency of the United Kingdom (United Kingdom)

    2012-03-01

    Following exposure to high doses of ionizing radiation, due to an accident or during radiotherapy, bystander signalling poses a potential hazard to unirradiated cells and tissues. This process can be mediated by factors circulating in blood plasma. Thus, we assessed the ability of plasma taken from in vitro irradiated human blood to produce a direct cytotoxic effect, by inducing apoptosis in primary human peripheral blood mononuclear cells (PBM), which mainly comprised G{sub 0}-stage lymphocytes. Plasma was collected from healthy donors' blood irradiated in vitro to 0-40 Gy acute {gamma}-rays. Reporter PBM were separated from unirradiated blood with Histopaque and held in medium with the test plasma for 24 h at 37 Degree-Sign C. Additionally, plasma from in vitro irradiated and unirradiated blood was tested against PBM collected from blood given 4 Gy. Apoptosis in reporter PBM was measured by the Annexin V test using flow cytometry. Plasma collected from unirradiated and irradiated blood did not produce any apoptotic response above the control level in unirradiated reporter PBM. Surprisingly, plasma from irradiated blood caused a dose-dependent reduction of apoptosis in irradiated reporter PBM. The yields of radiation-induced cell death in irradiated reporter PBM (after subtracting the respective values in unirradiated reporter PBM) were 22.2 {+-} 1.8% in plasma-free cultures, 21.6 {+-} 1.1% in cultures treated with plasma from unirradiated blood, 20.2 {+-} 1.4% in cultures with plasma from blood given 2-4 Gy and 16.7 {+-} 3.2% in cultures with plasma from blood given 6-10 Gy. These results suggested that irradiated blood plasma did not cause a radiation-induced bystander cell-killing effect. Instead, a reduction of apoptosis in irradiated reporter cells cultured with irradiated blood plasma has implications concerning oncogenic risk from mutated cells surviving after high dose in vivo irradiation (e.g. radiotherapy) and requires further study.

  17. 42 CFR 84.206 - Particulate tests; respirators with filters; minimum requirements; general.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Particulate tests; respirators with filters... RESPIRATORY PROTECTIVE DEVICES Chemical Cartridge Respirators § 84.206 Particulate tests; respirators with filters; minimum requirements; general. (a) Three respirators with cartridges containing, or...

  18. 42 CFR 84.201 - Head harnesses; minimum requirements.

    Science.gov (United States)

    2010-10-01

    ... Cartridge Respirators § 84.201 Head harnesses; minimum requirements. (a)(1) Facepieces for chemical cartridge respirators other than single-use vinyl chloride shall be equipped with adjustable and replaceable... chloride respirators shall be equipped with adjustable head harnesses designed and constructed to...

  19. On-line coupling of solid-phase extraction with mass spectrometry for the analysis of biological samples. II. Determination of clenbuterol in urine using multiple-stage mass spectrometry in an ion-trap mass spectrometer

    NARCIS (Netherlands)

    van Hout, MWJ; Hofland, CM; Niederlander, HAG; de Jong, GJ

    2000-01-01

    Solid-phase extraction (SPE) was coupled to ion-trap mass spectrometry to determine clenbuterol in urine. For SPE a cartridge exchanger was used and, after extraction, the eluate was directly introduced into the mass spectrometer, For two types of cartridges, i.e. C-18 and polydivinylbenzene (PDVB),

  20. A Modern Apparatus for Performing Flash Chromatography: An Experiment for the Organic Laboratory

    Science.gov (United States)

    Naumiec, Gregory R.; Del Padre, Angela N.; Hooper, Matthew M.; Germaine, Alison St.; DeBoef, Brenton

    2013-01-01

    A modern apparatus for performing flash chromatography using commercially available, prepacked silica cartridges has been developed. The key advantage of this system, when compared to traditional flash chromatography, is its use of commercially available silica cartridges, which obviates the need for students to handle silica gel. The apparatus…

  1. 75 FR 5586 - Notice of a Regional Project Waiver of Section 1605 (Buy American Requirement) of the American...

    Science.gov (United States)

    2010-02-03

    ..., New Jersey, for the purchase of a membrane bio-reactor (MBR) unit that uses flat- plate membrane... utilizing flat-plate membrane cartridges. No United States manufacturer produces a MBR unit with flat-plate membrane cartridges that meet the specifications for the project. The only MBR unit that incorporates the...

  2. 77 FR 4006 - Foreign-Trade Zone 45-Portland, Oregon; Expansion of Manufacturing Authority; Epson Portland, Inc...

    Science.gov (United States)

    2012-01-26

    ...), warehousing and distribution of inkjet printer cartridges. The current request involves the production of ink...) of ink per year. The finished product would be either inkjet ink (duty rate-- 1.8%) or inkjet printer... inkjet ink (duty rate--1.8%) or inkjet printer cartridges (duty-free) for the additional foreign...

  3. 76 FR 81475 - Foreign-Trade Zone 45-Portland, OR

    Science.gov (United States)

    2011-12-28

    ... privileged foreign (PF) status (19 CFR 146.41) inputs in manufacturing of ink for inkjet printer cartridges... would be either inkjet ink (duty rate--1.8%) or inkjet printer cartridges (duty- free). New material... Portland Inc. ] (Inkjet Ink Manufacturing), Hillsboro, OR An application has been submitted to the...

  4. 78 FR 290 - National Conference on Weights and Measures 98th Interim Meeting

    Science.gov (United States)

    2013-01-03

    ...-metering applications and the use of Global Positioning System (GPS) devices for fare determinations in the... contents of printer ink and toner cartridges. These notices are intended to make interested parties aware.... Item 232-6: Packaged Printer Ink and Toner Cartridges This proposal was originally intended...

  5. Effect of gamma irradiation on microbial load and sensory characteristics of aniseed (Pimpinella anisum).

    Science.gov (United States)

    Al-Bachir, M

    2007-07-01

    Seeds of anise (Pimpinella anisum) were exposed to doses of 0, 5, 10, 15 and 20kGy in a (60)Co package irradiator. Irradiated and unirradiated samples were stored at room temperature. Microbial populations on seeds, total and inorganic soluble solids in water extract and sensory properties of the latter were evaluated after 0, 6 and 12 months of storage. Results indicated that gamma irradiation reduced the aerobic plate counts of aniseed. Immediately after irradiation, the total soluble solids in an extract of irradiated seeds were greater than those of unirradiated ones. The total soluble solids in an extract of irradiated and un-irradiated seeds increased after 6 and 12 months of storage. There were no significant differences (p>0.05) in inorganic soluble solids between the water extract of irradiated and unirradiated aniseeds. Sensory evaluation indicated that gamma irradiation improved sensory characteristics of aniseed water extract tested immediately after irradiation; however, after 12 months of storage, no significant differences (p>0.05) were found in color, taste or flavor between extract of irradiated and unirradiated seeds.

  6. Application of subsize specimens in nuclear plant life extension

    Energy Technology Data Exchange (ETDEWEB)

    Rosinski, S.T. [Sandia National Labs., Albuquerque, NM (United States); Kumar, A.S. [Missouri Univ., Rolla, MO (United States); Cannon, S.C. [Westinghouse Hanford Co., Richland, WA (United States); Hamilton, M.L. [Pacific Northwest Lab., Richland, WA (United States)

    1991-12-31

    The US Department of Energy is sponsoring a research effort through Sandia National Laboratories and the University of Missour-Rolla to test a correlation for the upper shelf energy (USE) values obtained from the impact testing of subsize Charpy V-notch specimens to those obtained from the testing of full size samples. The program involves the impact testing of unirradiated and irradiated full, half, and third size Charpy V-notch specimens. To verify the applicability of the correlation on LWR materials unirradiated and irradiated full, half, and third size Charpy V-notch specimens of a commercial pressure vessel steel (ASTM A533 Grade B) will be tested. This paper will provide details of the program and present results obtained from the application of the developed correlation methodology to the impact testing of the unirradiated full, half, and third size A533 Grade B Charpy V-notch specimens.

  7. Application of subsize specimens in nuclear plant life extension

    Energy Technology Data Exchange (ETDEWEB)

    Rosinski, S.T. (Sandia National Labs., Albuquerque, NM (United States)); Kumar, A.S. (Missouri Univ., Rolla, MO (United States)); Cannon, S.C. (Westinghouse Hanford Co., Richland, WA (United States)); Hamilton, M.L. (Pacific Northwest Lab., Richland, WA (United States))

    1991-01-01

    The US Department of Energy is sponsoring a research effort through Sandia National Laboratories and the University of Missour-Rolla to test a correlation for the upper shelf energy (USE) values obtained from the impact testing of subsize Charpy V-notch specimens to those obtained from the testing of full size samples. The program involves the impact testing of unirradiated and irradiated full, half, and third size Charpy V-notch specimens. To verify the applicability of the correlation on LWR materials unirradiated and irradiated full, half, and third size Charpy V-notch specimens of a commercial pressure vessel steel (ASTM A533 Grade B) will be tested. This paper will provide details of the program and present results obtained from the application of the developed correlation methodology to the impact testing of the unirradiated full, half, and third size A533 Grade B Charpy V-notch specimens.

  8. Methanol adsorption on /γ-irradiated SiO2 surface

    Science.gov (United States)

    Novák, Éva; Hancz, András; Erdöhelyi, András

    2003-01-01

    The adsorption of methanol on γ-irradiated and un-irradiated SiO 2 surfaces pretreated at 473 K was investigated by Fourier transform infrared spectroscopy, temperature programmed desorption (TPD) and pulse methods. Methanol adsorbed only in molecular form on the un-irradiated sample. Treating the pre-irradiated silica surface with methanol at room temperature formaldehyde and hydrogen were formed. The methanol adsorbed on the irradiated silica transformed to formyl groups during a longer time at room temperature and desorbed as formaldehyde simultaneously with CH 3OH ( Tmax=395 K) on the TPD.

  9. Secondary Structure Alterations of Histones H2A and H2B in X-Irradiated Human Cancer Cells: Altered Histones Persist in Cells for at Least 24 Hours.

    Science.gov (United States)

    Izumi, Yudai; Yamamoto, Satoshi; Fujii, Kentaro; Yokoya, Akinari

    2015-11-01

    We measured and compared the circular dichroism (CD) spectra and secondary structures of histone proteins H2A, H2B and their variants extracted from X-irradiated and unirradiated human HeLa cells. Compared to unirradiated cells, a relative increase in α-helix structure and decrease in other secondary structures was observed in X-irradiated cells. These structural alterations persisted for at least 24 h, which is substantially longer than the 2 h generally known to be required for DNA double-strand break repair.

  10. Mutagenicity studies on alcohol extracts from gamma-irradiated potatoes. Dominant lethal test in mice

    Energy Technology Data Exchange (ETDEWEB)

    Shibuya, T.; Murora, T.; Iwahara, S.; Hashimoto, K. (Food and Drug Safety Center, Kanagawa (Japan). Hatano Research Inst.); Minegishi, A.

    1982-02-01

    Alcohol extracts freshly prepared from gamma-irradiated and unirradiated potatoes were tested for the ability to induce dominant lethals in BDF/sub 1/ mice. Male mice were given 0.5 ml of extract twice a day, p.o., for 7 days and then mated with untreated female mice. Female mice were sacrificed on about the 13th day of pregnancy. No significant difference was observed in the number of living inplants between the group treated with extract prepared from unirradiated potatoes and that treated with the extract from 150 Gy (15 krad) irradiated potatoes.

  11. Positron annihilation and thermally stimulated current of electron beam irradiated polyetheretherketone

    Energy Technology Data Exchange (ETDEWEB)

    Fujita, Shigetaka; Shinyama, Katsuyoshi; Baba, Makoto [Hachinohe Inst. of Tech., Hachinohe, Aomori (Japan); Suzuki, Takenori

    1997-03-01

    Positron lifetime measurements were applied to electron beam irradiated poly(ether-ether-ketone). The lifetime, {tau}{sub 3}, of the ortho-positronium of unirradiated and 5 MGy irradiated specimen became rapidly longer above about 150degC. {tau}{sub 3} of 50 MGy and 100 MGy irradiated specimen was shorter than that of unirradiated one. Thermally stimulated current (TSC) decreased with increasing the dose before voltage application. In the case of voltage application, a TSC peak appeared and the peak value decreased with increased the dose. The correlation between the results of positron annihilation and TSC was investigated. (author)

  12. Reference ballistic imaging database performance.

    Science.gov (United States)

    De Kinder, Jan; Tulleners, Frederic; Thiebaut, Hugues

    2004-03-10

    Ballistic imaging databases allow law enforcement to link recovered cartridge cases to other crime scenes and to firearms. The success of these databases has led many to propose that all firearms in circulation be entered into a reference ballistic image database (RBID). To assess the performance of an RBID, we fired 4200 cartridge cases from 600 9mm Para Sig Sauer model P226 series pistols. Each pistol fired two Remington cartridges, one of which was imaged in the RBID, and five additional cartridges, consisting of Federal, Speer, Winchester, Wolf, and CCI brands. Randomly selected samples from the second series of Remington cartridge cases and from the five additional brands were then correlated against the RBID. Of the 32 cartridges of the same make correlated against the RBID, 72% ranked in the top 10 positions. Likewise, of the 160 cartridges of the five different brands correlated against the database, 21% ranked in the top 10 positions. Generally, the ranking position increased as the size of the RBID increased. We obtained similar results when we expanded the RBID to include firearms with the same class characteristics for breech face marks, firing pin impressions, and extractor marks. The results of our six queries against the RBID indicate that a reference ballistics image database of new guns is currently fraught with too many difficulties to be an effective and efficient law enforcement tool.

  13. Water reactive hydrogen fuel cell power system

    Science.gov (United States)

    Wallace, Andrew P; Melack, John M; Lefenfeld, Michael

    2014-01-21

    A water reactive hydrogen fueled power system includes devices and methods to combine reactant fuel materials and aqueous solutions to generate hydrogen. The generated hydrogen is converted in a fuel cell to provide electricity. The water reactive hydrogen fueled power system includes a fuel cell, a water feed tray, and a fuel cartridge to generate power for portable power electronics. The removable fuel cartridge is encompassed by the water feed tray and fuel cell. The water feed tray is refillable with water by a user. The water is then transferred from the water feed tray into a fuel cartridge to generate hydrogen for the fuel cell which then produces power for the user.

  14. Investigation of welding and brazing of molybdenum and TZM alloy tubes

    Science.gov (United States)

    Lundblad, Wayne E.

    1991-01-01

    This effort involved investigating the welding and brazing techniques of molybdenum tubes to be used as cartridges in the crystal growth cartridge. Information is given in the form of charts and photomicrographs. It was found that the recrystallization temperature of molybdenum can be increased by alloying it with 0.5 percent titanium and 0.1 percent zirconium. Recrystallization temperatures for this alloy, known as TZM, become significant around 2500 F. A series of microhardness tests were run on samples of virgin and heat soaked TZM. The test results are given in tabular form. It was concluded that powder metallurgy TZM may be an acceptable cartridge material.

  15. Estimation of Heat Loss in a Closed Vessel

    Directory of Open Access Journals (Sweden)

    B. A. Parate

    2007-03-01

    Full Text Available Power cartridges are designed and developed for use in military aircraft in association withHigh Energy Materials Research Laboratory, Pune. During development, the cartridge is firedin a closed vessel to generate basic design parameters. When the cartridge is fired, the heat islost to the walls of the vessel due to conduction, convection, radiation, and to some extent, byexpansion of the vessel. An attempt has been made to estimate the heat loss from the vesseland the surrounding. The aim of this study was to lay down the technical results theoreticallyand their validation through experiments.

  16. Automated measurement system employing eddy currents to adjust probe position and determine metal hardness

    Science.gov (United States)

    Prince, James M.; Dodson, Michael G.; Lechelt, Wayne M.

    1989-01-01

    A system for measuring the hardness of cartridge cases employs an eddy current probe for inducing and sensing eddy currents in each cartridge case. A first component of the sensed signal is utilized in a closed loop system for accurately positioning the probe relative to the cartridge case both in the lift off direction and in the tangential direction, and a second component of the sensed signal is employed as a measure of the hardness. The positioning and measurement are carried out under closed loop microprocessor control facilitating hardness testing on a production line basis.

  17. Full automation of {sup 68}Ga labelling of DOTA-peptides including cation exchange prepurification

    Energy Technology Data Exchange (ETDEWEB)

    Ocak, M. [Clinical Department of Nuclear Medicine, Medical University Innsbruck, Anichstrasse 35, A-6020 Innsbruck (Austria); Department of Pharmaceutical Technology, Pharmacy Faculty, Istanbul University, Istanbul (Turkey); Antretter, M. [Clinical Department of Nuclear Medicine, Medical University Innsbruck, Anichstrasse 35, A-6020 Innsbruck (Austria); Knopp, R.; Kunkel, F. [Eckert and Ziegler Eurotope GmbH, Berlin (Germany); Petrik, M. [Clinical Department of Nuclear Medicine, Medical University Innsbruck, Anichstrasse 35, A-6020 Innsbruck (Austria); Bergisadi, N. [Department of Pharmaceutical Technology, Pharmacy Faculty, Istanbul University, Istanbul (Turkey); Decristoforo, C. [Clinical Department of Nuclear Medicine, Medical University Innsbruck, Anichstrasse 35, A-6020 Innsbruck (Austria)], E-mail: Clemens.Decristoforo@uki.at

    2010-02-15

    Here we describe a fully automated approach for the synthesis of {sup 68}Ga-labelled DOTA-peptides based on pre-concentration and purification of the generator eluate by using a cation exchange-cartridge and its comparison with fully automated direct labelling applying fractionated elution. Pre-concentration of the eluate on a cation exchange cartridge both using a resin-based and a disposable cation-exchange cartridge efficiently removed {sup 68}Ge as well as major metal contaminations with Fe and Zn. This resulted in a high labelling efficiency of DOTA-peptides at high specific activity (SA) with short synthesis times.

  18. Water reactive hydrogen fuel cell power system

    Science.gov (United States)

    Wallace, Andrew P; Melack, John M; Lefenfeld, Michael

    2014-11-25

    A water reactive hydrogen fueled power system includes devices and methods to combine reactant fuel materials and aqueous solutions to generate hydrogen. The generated hydrogen is converted in a fuel cell to provide electricity. The water reactive hydrogen fueled power system includes a fuel cell, a water feed tray, and a fuel cartridge to generate power for portable power electronics. The removable fuel cartridge is encompassed by the water feed tray and fuel cell. The water feed tray is refillable with water by a user. The water is then transferred from the water feed tray into the fuel cartridge to generate hydrogen for the fuel cell which then produces power for the user.

  19. Amplification of Tau fibrils from minute quantities of seeds.

    Science.gov (United States)

    Meyer, Virginia; Dinkel, Paul D; Rickman Hager, Emily; Margittai, Martin

    2014-09-16

    The propagation of Tau pathology in Alzheimer's disease (AD) is thought to proceed through templated conversion of Tau protein into fibrils and cell-to-cell transfer of elongation-competent seeds. To investigate the efficiency of Tau conversion, we adapted the protein misfolding cyclic amplification assay used for the conversion of prions. Utilizing heparin as a cofactor and employing repetitive cycles of shearing and growth, synthetic Tau fibrils and Tau fibrils in AD brain extract are progressively amplified. Concurrently, self-nucleation is suppressed. The results highlight breakage-induced replication of Tau fibrils as a potential facilitator of disease spread.

  20. The Effect of Orientation Relaxation on Polymer Melt Crystallization Studied by Monte Carlo Simulations

    Institute of Scientific and Technical Information of China (English)

    WANG Mao-Xiang

    2009-01-01

    We use dynamic Monte Carlo simulations to study the athermal relaxation of bulk extended chains and the isothermal crystallization in intermediately relaxed melts. It is found that the memory of chain orientations in the melt can significantly enhance the crystallization rates. The crystal orientation and lamellar thickness essentially depend on the orientational relaxation. Moreover, there is a transition of the nucleation mechanism during the isothermal crystallization from the intermediately relaxed melts. These results explain the mechanism of the self-nucleation by orientation and suggest that in flow-induced polymer crystallization, the orientational relaxation of chains decides the crystal orientation.

  1. Studio di un algoritmo lineare di ricostruzione analogica della posizione per il rivelatore a pixel di ATLAS

    CERN Document Server

    Arelli-Maffioli, A; Troncon, C; Lari, T

    2007-01-01

    A detailed study of spatial resolution of Atlas pixel sensors prototypes was performed. Charge interpolation was used and allowed for a significant improvement with respect to digital resolution. A simplified algorithm for charge interpolation was developed. Its application to both unirradiated and irradiated sensors is presented and discussed.

  2. Irradiation of onions on a large scale

    Energy Technology Data Exchange (ETDEWEB)

    Kawashima, Koji; Hayashi, Toru; Uozumi, J.; Sugimoto, Toshio; Aoki, Shohei

    1984-03-01

    A large number of onions of var. Kitamiki and Ohotsuku were irradiated in September followed by storage at 0 deg C or 5 deg C. The onions were shifted from cold-storage facilities to room temperature in mid-March or in mid-April in the following year. Their sprouting, rooting, spoilage characteristics and sugar content were observed during storage at room temperature. Most of the unirradiated onions sprouted either outside or inside bulbs during storage at room temperature, and almost all of the irradiated ones showed small buds with browning inside the bulb in mid-April irrespective of the storage temperature. Rooting and/or expansion of bottom were observed in the unirradiated samples. Although the irradiated materials did not have root, they showed expansion of bottom to some extent. Both the irradiated and unirradiated onions spoiled slightly unless they sprouted, and sprouted onions were easily spoiled. There was no difference in the glucose content between the unirradiated and irradiated onions, but the irradiated ones yielded higher sucrose content when stored at room temperature. Irradiation treatment did not have an obvious effect on the quality of freeze-dried onion slices. (author).

  3. 10 CFR 50.61 - Fracture toughness requirements for protection against pressurized thermal shock events.

    Science.gov (United States)

    2010-01-01

    ... Nuclear Power Plant Components,” edition and addenda and any limitations and modifications thereof as...-service or unirradiated condition, evaluated according to the procedures in the ASME Code, Paragraph NB... continue to operate without justification. (b) Requirements. (1) For each pressurized water nuclear...

  4. Emergency response to a highway accident in Springfield, Massachusetts, on December 16, 1991

    Energy Technology Data Exchange (ETDEWEB)

    1992-06-01

    On December 16, 1991, a truck carrying unirradiated (fresh) nuclear fuel was involved in an accident on US Interstate 91, in Springfield, Massachusetts. This report describes the emergency response measures undertaken by local, State, Federal, and private parties. The report also discusses ``lessons learned`` from the response to the accident and suggests areas where improvements might be made.

  5. Emergency response to a highway accident in Springfield, Massachusetts, on December 16, 1991

    Energy Technology Data Exchange (ETDEWEB)

    1992-06-01

    On December 16, 1991, a truck carrying unirradiated (fresh) nuclear fuel was involved in an accident on US Interstate 91, in Springfield, Massachusetts. This report describes the emergency response measures undertaken by local, State, Federal, and private parties. The report also discusses lessons learned'' from the response to the accident and suggests areas where improvements might be made.

  6. Detection of Irradiation Treatment of Foods Using DNA `Comet Assay'

    Science.gov (United States)

    Khan, Hasan M.; Delincée, Henry

    1998-06-01

    Microgel electrophoresis of single cells (DNA comet assay) has been investigated to detect irradiation treatment of some food samples. These samples of fresh and frozen rainbow trout, red lentil, gram and sliced almonds were irradiated to 1 or 2 kGy using 10 MeV electron beam from a linear accelerator. Rainbow trout samples yielded good results with samples irradiated to 1 or 2 kGy showing fragmentation of DNA and, therefore, longer comets with no intact cells. Unirradiated samples showed shorter comets with a significant number of intact cells. For rainbow trout stored in a freezer for 11 days the irradiated samples can still be discerned by electrophoresis from unirradiated samples, however, the unirradiated trouts also showed some longer comets besides some intact cells. Radiation treatment of red lentils can also be detected by this method, i.e. no intact cells in 1 or 2 kGy irradiated samples and shorter comets and some intact cells in unirradiated samples. However, the results for gram and sliced almond samples were not satisfactory since some intact DNA cells were observed in irradiated samples as well. Probably, incomplete lysis has led to these deviating results.

  7. Optical absorption and luminescence in neutron-irradiated, silica-based fibers

    Energy Technology Data Exchange (ETDEWEB)

    Cooke, D.W.; Farnum, E.H.; Clinard, F.W. [Los Alamos National Lab., CA (United States)] [and others

    1995-04-01

    The objectives of this work are to assess the effects of thermal annealing and photobleaching on the optical absorption of neutron-irradiated, silica fibers of the type proposed for use in ITER diagnostics, and to measure x-ray induced luminescence of unirradiated (virgin) and neutron-irradiated fibers.

  8. Proteome analysis of proliferative response of bystander cells adjacent to cells exposed to ionizing radiation.

    Science.gov (United States)

    Gerashchenko, Bogdan I; Yamagata, Akira; Oofusa, Ken; Yoshizato, Katsutoshi; de Toledo, Sonia M; Howell, Roger W

    2007-06-01

    Recently (Cytometry 2003, 56A, 71-80), we reported that direct cell-to-cell contact is required for stimulating proliferation of bystander rat liver cells (WB-F344) cocultured with irradiated cells, and neither functional gap junction intercellular communication nor long-range extracellular factors appear to be involved in this proliferative bystander response (PBR). The molecular basis for this response is unknown. Confluent monolayers of WB-F344 cells were exposed to 5-Gray (Gy) of gamma-rays. Irradiated cells were mixed with unirradiated cells and co-cultured for 24 h. Cells were harvested and protein expression was examined using 2-DE. Protein expression was also determined in cultures of unirradiated and 5-Gy irradiated cells. Proteins were identified by MS. Nucleophosmin (NPM)-1, a multifunctional nucleolar protein, was more highly expressed in bystander cells than in either unirradiated or 5-Gy irradiated cells. Enolase-alpha, a glycolytic enzyme, was present in acidic and basic variants in unirradiated cells. In bystander and 5-Gy irradiated cells, the basic variant was weakly expressed, whereas the acidic variant was overwhelmingly present. These data indicate that the presence of irradiated cells can affect NPM-1 and enolase-alpha in adjacent bystander cells. These proteins appear to participate in molecular events related to the PBR and suggest that this response may involve cellular defense, proliferation, and metabolism.

  9. Fast neutron sensitivity of dry and germinating tomato seeds

    NARCIS (Netherlands)

    Contant, R.B.

    1970-01-01

    A study was made of changes in fast neutron effectiveness during the hydration and germination of tomato seeds. The main findings and conclusions are the following,

    Section 3.6

    Samples of unirradiated seeds and their constituent parts (seedcoat+endosperm and embryo) were taken at short

  10. Characterization of blend hydrogels based on plasticized starch/cellulose acetate/carboxymethyl cellulose synthesized by electron beam irradiation

    Science.gov (United States)

    Senna, Magdy M.; Mostafa, Abo El-Khair B.; Mahdy, Sanna R.; El-Naggar, Abdel Wahab M.

    2016-11-01

    Blend hydrogels based on aqueous solutions of plasticized starch and different ratios of cellulose acetate (CA) and carboxymethyl cellulose (CMC) were prepared by electron beam irradiation (EB). The blends before and after EB irradiation were characterized by thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC). The physico-chemical properties of blend hydrogels prepared by electron beam irradiation were improved compared to unirradiated blends.

  11. Relations between the physiological state of onions and an effective sprout inhibition by irradiation

    Science.gov (United States)

    Dahlhelm, H.; Matejko, C.

    The mitotic activity in shoot meristem was examined during the entire storage period of onions ( Allium cepa L.) and was compared with the growth of the inner bud of the bulbs unirradiated and after irradiation. The meaning of cell division at the shoot apex for the sprouting of onions and the effect of γ-irradiation are discussed.

  12. An autonomic self-healing organogel with a photo-mediated modulus.

    Science.gov (United States)

    Xiong, Yubing; Chen, Zhijun; Wang, Hong; Ackermann, Lisa-Maria; Klapper, Markus; Butt, Hans-Jürgen; Wu, Si

    2016-12-01

    A new method is described for fabricating autonomic, self-healing, deformable organogels. We combined imidazolium-based poly(ionic liquid) (PIL) and azobenzene-grafted poly(carboxylic acid) (PAA-Azo) in N,N-dimethyl formamide. Further, complexing PIL with unirradiated (trans) or irradiated (cis) PAA-Azo tuned the elastic modulus of the organogel.

  13. Interlaboratory beta source calibration using TL and OSL on natural quartz

    DEFF Research Database (Denmark)

    Goksu. H.Y.; Bailiff, I.K.; Bøtter-Jensen, L.

    1995-01-01

    Laboratory at GSF using a Go-60 source as well as the in situ measurements with an ionization chamber, calibrated to the primary standards of PTB Braunschweig. Irradiated and unirradiated quartz was distributed to the five laboratories and although different procedures were used for thermoluminescence...

  14. [Optimal coefficient of overlap of light spots during laser hardening of medical instruments].

    Science.gov (United States)

    Stepanova, G A; Pogibenko, A V; Gerasev, G P

    1982-01-01

    The optimum coefficient of light spot intercepts in the course of laser hardening medical instruments is determined for the case when there are no unirradiated sites on the surface under treatment. The increase in the light spot diameter during irradiation has been shown to be followed by more rapid expansion of the hardened area in comparison with the one of the tempered zone.

  15. 10 CFR 110.21 - General license for the export of special nuclear material.

    Science.gov (United States)

    2010-01-01

    ... per year to any one country. (2) Special nuclear material in fuel elements as replacements for damaged or defective unirradiated fuel elements previously exported under a specific license, subject to the same terms as the original export license and the condition that the replaced fuel elements must...

  16. Relations between the physiological state of onions and an effective sprout inhibition by irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Dahlhelm, H.; Matejko, C. (Akademie der Wissenschaften der DDR, Leipzig (Germany, F.R.). Zentralinstitut fuer Isotopen- und Strahlenforschung)

    1990-01-01

    The mitotic activity in shoot meristem was examined during the entire storage period of onions (Allium cepa L.) and was compared with the growth of the inner bud of the bulbs unirradiated and after irradiation. The meaning of cell division at the shoot apex for the sprouting of onions and the effect of {gamma}-irradiation are discussed. (author).

  17. SCK-CEN Contribution to the''Relation between different measures of exposure-induced shifts in ductile-brittle transition temperatures'' (REFEREE). Progress Report

    Energy Technology Data Exchange (ETDEWEB)

    Chaouadi, R.; Van Walle, E.; Fabry, A.; Puzzolante, J.L

    1998-08-01

    The relationship between Charpy-V (CVN) impact, fracture toughness and tensile properties for selected reactor pressure -vessel steels in the transition temperature range are investigated. Data on the testing of unirradiated material are reported. The applied methods include chemical analysis, Charpy-V impact testing, tensile testing and fracture toughness determination.

  18. 10 CFR 140.3 - Definitions.

    Science.gov (United States)

    2010-01-01

    ... establishment in the executive branch of the Government. (f) Nuclear reactor means any apparatus, other than an... manufacture of reactor fuel containing plutonium, where the license or licenses authorize the possession of... otherwise sealed unirradiated or irradiated fuel rods, at the site of the plant or authorize the...

  19. Safety Analysis for Packaging Steel Banded Wooden Shipping Containers

    Energy Technology Data Exchange (ETDEWEB)

    FERRELL, P.C.

    2000-12-05

    This safety analysis report for packaging describes the steel banded wooden shipping containers, which are certified as Type AF packagings. The authorized payload for these containers is unirradiated, slightly enriched, uranium ingots, billets, extrusions, and scrap materials. The amount of uranium in the containers will not exceed the LSA-II material requirements as defined in 49 CFR 173.403.

  20. Insulin Lispro Injection

    Science.gov (United States)

    ... is a short-acting, man-made version of human insulin. Insulin lispro works by replacing the insulin ... received the right type of insulin from the pharmacy.Insulin lispro comes in vials, cartridges that contain ...

  1. 42 CFR 84.195 - Breathing tubes; minimum requirements.

    Science.gov (United States)

    2010-10-01

    ... Cartridge Respirators § 84.195 Breathing tubes; minimum requirements. Flexible breathing tubes used in conjunction with respirators shall be designed and constructed to prevent: (a) Restriction of free...

  2. 42 CFR 84.1131 - Respirators; required components.

    Science.gov (United States)

    2010-10-01

    ... SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Dust, Fume... noseclip, hood, or helmet; (2) Filter unit, canister with filter, or cartridge with filter; (3) Harness;...

  3. Sun StorageTek T9940 Tape Drive

    CERN Multimedia

    2002-01-01

    Technology allowed reuse of the same data cartridge at higher capacity with later model of the tape drive hence offering significant savings of the media cost. It has been use by the CERN from 2002 to 2008.

  4. Brief Guide to Mold, Moisture, and Your Home

    Science.gov (United States)

    ... plastic or rubber and have removable cartridges that trap most of the mold spores from entering. In ... thank Paul Ellringer, PE, CIH, for providing the photo of Mold growing on the back side of ...

  5. [Modern methods of examination of ballistic trauma after passing through the barrier].

    Science.gov (United States)

    Titov, R v; Tiurin, M V; Kabanov, M Iu; Nepomniashchiĭ, S A; Smolin, N V; Nagut, N N; Soroka, A K; Nikolaev, I K

    2014-07-01

    On the basis of experimental data were studied peculiarities of ballistic of wounds after passing barriers. Authors analyzed forensic medical examination reports concerned about murdered and wounded with gunshots in Saint Petersburg. As research objects were used: simulators of biological materials (block of glycerin soap) and experimental animals. The following bullets were used: automat cartridge 7H22, 7H24 - gauge 5,45x39 mm, pistol cartridge 7H29 - gauge 9,0x21 mm; gun reach - 50 and 100 meters; barriers - steel plates, glass, brickwork. The following assessment of exposure was used: in simulators - according to volumes of temporary cavity; in experimental animals - according to results of morphofunctional researches. Data about damaging action of pistol cartridge 7H22, 7H24 with gauge 5,45 mm and automat cartridges 7H29 and 9,0 mm is received.

  6. 76 FR 540 - National Conference on Weights and Measures 2011 Interim Meeting

    Science.gov (United States)

    2011-01-05

    ... Method of Sale Regulation for Packages of Printer Ink and Toner Cartridges--The L&R Committee will... products so value comparisons can be made. Special Meeting Announcements The Task Group on Printer Ink...

  7. [Marks on clothing and skin in absolutely and relatively close distance gunshots with fright weapons].

    Science.gov (United States)

    Nadjem, H; Bohnert, M; Schley, K; Pollak, S

    1996-01-01

    Based on an actual case to be examined-the victim had sustained burning and powder tattooing of the abdominal skin--test shots were performed with blank cartridge guns (Mauser and Umarex revolvers, cal. 380) in order to study the changes occurring on textiles in the area of contact and close range shots. As expected, the extent of burning and smoke soiling depended on whether the propellant of the blank cartridges consisted of nitrocellulose (Nc) or black powder. At the same distance the smokeless nitro-powder caused less soot soiling and burning than black powder. Contact or near contact shots produced tear-like tissue damages due to the pressure of the discharged muzzle gases. When black powder cartridges were used, burn holes larger than the caliber were observed; with Nc blank cartridges the thermal effects were most pronounced if textiles made of thermolabile synthetics were shot at.

  8. DETERMINATION OF METAL HYDRIDE SYSTEMS CHARACTERISTICS WHILE HEATING

    Directory of Open Access Journals (Sweden)

    Yu. Kluchka

    2012-01-01

    Full Text Available Experimental dependence of the pressure of hydrogen in the hydride cartridge when it is heated is obtained. Experimental data prove the theoretical values with an accuracy of ≈ 6%.

  9. Fluid delivery manifolds and microfluidic systems

    Energy Technology Data Exchange (ETDEWEB)

    Renzi, Ronald F.; Sommer, Gregory J.; Singh, Anup K.; Hatch, Anson V.; Claudnic, Mark R.; Wang, Ying-Chih; Van de Vreugde, James L.

    2017-02-28

    Embodiments of fluid distribution manifolds, cartridges, and microfluidic systems are described herein. Fluid distribution manifolds may include an insert member and a manifold base and may define a substantially closed channel within the manifold when the insert member is press-fit into the base. Cartridges described herein may allow for simultaneous electrical and fluidic interconnection with an electrical multiplex board and may be held in place using magnetic attraction.

  10. Plastic Media Blasting Data Gathering Study

    Science.gov (United States)

    1986-12-01

    matt, reducing the filtering surface. 25 3) Cartridge Collectors: Cartridge dust collectors consist of a number of nonwoven tubular filters placed...Engineering Command 03 SPLASTIC MEDIA BLASTING DATA GATHERING STUDY: FINAL REPORT ABSTRAC>lastic Media Blasting (PMB) is proving to be a cost effective method...facilities; needed blasting and media recovery equipment; different types of media ; and media disposal. The Economics section gives two examples of economic

  11. Nitrogen dioxide reducing ascorbic acid technologies in the ventilator circuit leads to uniform NO concentration during inspiration.

    Science.gov (United States)

    Pezone, Matthew J; Wakim, Matthew G; Denton, Ryan J; Gamero, Lucas G; Roscigno, Robert F; Gilbert, Richard J; Lovich, Mark A

    2016-08-31

    Conventional inhaled NO systems deliver NO by synchronized injection or continuous NO flow in the ventilator circuitry. Such methods can lead to variable concentrations during inspiration that may differ from desired dosing. NO concentrations in these systems are generally monitored through electrochemical methods that are too slow to capture this nuance and potential dosing error. A novel technology that reduces NO2 into NO via low-resistance ascorbic-acid cartridges just prior to inhalation has recently been described. The gas volume of these cartridges may enhance gas mixing and reduce dosing inconsistency throughout inhalation. The impact of the ascorbic-acid cartridge technology on NO concentration during inspiration was characterized through rapid chemiluminescence detection during volume control ventilation, pressure control ventilation, synchronized intermittent mandatory ventilation and continuous positive airway pressure using an in vitro lung model configured to simulate the complete uptake of NO. Two ascorbic acid cartridges in series provided uniform and consistent dosing during inspiration during all modes of ventilation. The use of one cartridge showed variable inspiratory concentration of NO at the largest tidal volumes, whereas the use of no ascorbic acid cartridge led to highly inconsistent NO inspiratory waveforms. The use of ascorbic acid cartridges also decreased breath-to-breath variation in SIMV and CPAP ventilation. The ascorbic-acid cartridges, which are designed to convert NO2 (either as substrate or resulting from NO oxidation during injection) into NO, also provide the benefit of minimizing the variation of inhaled NO concentration during inspiration. It is expected that the implementation of this method will lead to more consistent and predictable dosing.

  12. Bastion on the Border: Fort Bliss, 1854-1943

    Science.gov (United States)

    1993-01-01

    THE BORDER border. Several smuggling rings even made canvas vests for their runners to wear so they could carry more cartridges per trip. There was...no lack of runners , especially among destitute Mexican refugees eager to earn a few cents per cartridge for carrying ammunition. They knew that if they...Aftermath /99 cavalry found it difficult to maneuver in a maze of irrigation ditches. Accordingly the Villistas were not crushed, but they were completely

  13. Advancements in Neutron Radiography within the Department of the Army

    Science.gov (United States)

    2014-12-29

    mines, medium caliber cartridges , mortars, and large caliber rounds have or are being designed to be anti-personnel devices. Such designs use...Radiographs of layered materials, depicting reduced effectiveness using x-rays. 40mm high explosive, dual purpose (HEDP) cartridge M433 (left). http://media...Mega-, 1E6 m meter MCNP Monte Carlo N-Particle software n neutron NC Neutron Content, thermal NDT Nondestructive Testing NR Neutron

  14. Emissions of Nanoparticles and Gaseous Material from 3D Printer Operation.

    Science.gov (United States)

    Kim, Yuna; Yoon, Chungsik; Ham, Seunghon; Park, Jihoon; Kim, Songha; Kwon, Ohhun; Tsai, Perng-Jy

    2015-10-20

    This study evaluated the emissions characteristics of hazardous material during fused deposition modeling type 3D printing. Particulate and gaseous materials were measured before, during, and after 3D printing in an exposure chamber. One ABS and two PLA (PLA1 and PLA2) cartridges were tested three times. For online monitoring, a scanning mobility particle sizer, light scattering instrument, and total volatile organic compound (TVOC) monitor were employed and a polycarbonate filter and various adsorbent tubes were used for offline sampling. The particle concentration of 3D printing using ABS material was 33-38 times higher than when PLA materials were used. Most particles were nanosize (<100 nm) during ABS (96%) and PLA1 (98%) use, but only 12% were nanosize for PLA2. The emissions rates were 1.61 × 10(10) ea/min and 1.67 × 10(11) ea/g cartridge with the ABS cartridge and 4.27-4.89 × 10(8) ea/min and 3.77-3.91 × 10(9) ea/g cartridge with the PLA cartridge. TVOCs were also emitted when the ABS was used (GM; 155 ppb, GSD; 3.4), but not when the PLA cartridges were used. Our results suggest that more research and sophisticated control methods, including the use of less harmful materials, blocking emitted containments, and using filters or adsorbents, should be implemented.

  15. Evaluation of the limulus amoebocyte lysate test in conjunction with a gram negative bacterial plate count for detecting irradiation of chicken

    Science.gov (United States)

    Scotter, Susan L.; Wood, Roger; McWeeny, David J.

    A study to evaluate the potential of the Limulus amoebocyte lysate (LAL) test in conjuction with a Gram negative bacteria (GNB) plate count for detecting the irradiation of chicken is described. Preliminary studies demonstrated that chickens irradiated at an absorbed dose of 2.5 kGy could be differentiated from unirradiated birds by measuring levels of endotoxin and of numbers of GNB on chicken skin. Irradiated birds were found to have endotoxin levels similar to those found in unirradiated birds but significantly lower numbers of GNB. In a limited study the test was found to be applicable to birds from different processors. The effect of temperature abuse on the microbiological profile, and thus the efficacy of the test, was also investigated. After temperature abuse, the irradiated birds were identifiable at worst up to 3 days after irradiation treatment at the 2.5 kGy level and at best some 13 days after irradiation. Temperature abuse at 15°C resulted in rapid recovery of surviving micro-organisms which made differentiation of irradiated and unirradiated birds using this test unreliable. The microbiological quality of the bird prior to irradiation treatment also affected the test as large numbers of GNB present on the bird prior to irradiation treatment resulted in larger numbers of survivors. In addition, monitoring the developing flora after irradiation treatment and during subsequent chilled storage also aided differentiation of irradiated and unirradiated birds. Large numbers of yeasts and Gram positive cocci were isolated from irradiated carcasses whereas Gram negative oxidative rods were the predominant spoilage flora on unirradiated birds.

  16. Identification of radiation treatment of wheat (Triticum aestivum. L) and rice (Oryza sativa. L) samples using thermoluminescence of contaminating minerals

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Food irradiation is gaining popularity worldwide and this technology is important to improve quality and reduce the post harvest losses of food. Because of the rapid commercialization of irradiated foods throughout the world, compliance of different regulations relating to use of technology in different countries and demand of consumers for clear labelling of irradiated foods, there is need for the development of analytical methods to detect radiation treatment of food. Among several methods studied so far, thermoluminescence (TL) is an important method that can be used to find out the irradiation history of food that contain even a very minute amount of dust particles. In this study, the irradiated and unirradiated wheat and rice samples were analyzed using the TL method. The samples were purchased from the local market of Peshawar and irradiated to radiation doses of 0.5 and 1.0 kGy using Co-60 gamma irradiator at the Nuclear Institute for Food and Agriculture (NIFA), Peshawar. The mineral contaminants were isolated by jet water, ultrasonic treatment, and density gradient. TL glow curves of the isolated minerals from irradiated and unirradiated samples were recorded between the temperature ranges of 50-500℃ using a TL reader. Generally, the glow curves for irradiated samples showed much higher TL intensities (TL1) than the unirradiated samples. The results were normalized by re-irradiation of mineral samples to gamma-ray dose of 1.0 kGy followed by determination of the second glow curves (TL2). The ratio of the area of first glow curve to that of second glow curve (TLl/TL2) was calculated for selected temperature intervals and compared with the recommended values for unirradiated and irradiated samples. Finally, the shapes of the glow curves for irradiated and unirradiated samples were also analyzed. On the basis of these results (comparison of TL-intensities, TL1/TL2 ratios and shapes of the glow curves), all the irradiated and unirradiated samples of wheat

  17. Pre-concentration of pesticide residues in environmental water samples using Silica nanoparticles and identification of residues By GC-MS method

    Directory of Open Access Journals (Sweden)

    Tentu. Nageswara Rao

    2016-08-01

    Full Text Available The silica nanoparticles prepared by stober’s mechanism by reaction of tetraethylorthosilicate (TEOS with ammonia was tested for their adsorption capacity in the pre-concentration of residues of pesticides in water. The synthesized nanoparticles were characterized by Scanning Electron Microscope (SEM, Transmission Electron Microscope (TEM and X-Ray Diffraction (XRD. The size of the silica nanoparticles were 50 to 250 nm. The solid phase extraction (SPE cartridges were prepared by filling the empty cartridges of 5.5 cm length and 0.3 cm i.d. with 200 mg of nanoparticles and protected between two polytetrafluroethylene (PTFE frits. To avoid the passage of nanoparticles, 2% solution of polystyrene in chloroform was passed through PTFE frits and dried in air for two hours at room temperature before fitted into the cartridges. This process is to reduce the pore size of the PTFE frits. These cartridges are used in pre-concentration of different types of residues of pesticides in water. The pyrethroids tested for the pre-concentration are tetramethrin, lambda-cyhalothrin, cyphenothrin. The water samples were spiked with aliquots of pesticides and were passed through the cartridges. The amounts of the pesticides adsorbed on the cartridges were tested. The influence of temperature, sample volume, flow rate, pH and ionic strength on the performance of the cartridges was checked. The results of fortified sample analysis were compared with the data obtained from the commercially available C18 cartridges for the sample volume. The separation parameters were established for the simultaneous determination of residues using GC-EI-MS. The method was validated by means of linearity, precision, and assay accuracy. The limit of detection (LOD and the limit of quantification (LOQ were established based on the signal to noise ratio 3:1 and 10:1 respectively. An analytical method for the enrichment of residues using nanoparticles based SPE cartridges were developed

  18. Automated Aflatoxin Analysis Using Inline Reusable Immunoaffinity Column Cleanup and LC-Fluorescence Detection.

    Science.gov (United States)

    Rhemrev, Ria; Pazdanska, Monika; Marley, Elaine; Biselli, Scarlett; Staiger, Simone

    2015-01-01

    A novel reusable immunoaffinity cartridge containing monoclonal antibodies to aflatoxins coupled to a pressure resistant polymer has been developed. The cartridge is used in conjunction with a handling system inline to LC with fluorescence detection to provide fully automated aflatoxin analysis for routine monitoring of a variety of food matrixes. The handling system selects an immunoaffinity cartridge from a tray and automatically applies the sample extract. The cartridge is washed, then aflatoxins B1, B2, G1, and G2 are eluted and transferred inline to the LC system for quantitative analysis using fluorescence detection with postcolumn derivatization using a KOBRA® cell. Each immunoaffinity cartridge can be used up to 15 times without loss in performance, offering increased sample throughput and reduced costs compared to conventional manual sample preparation and cleanup. The system was validated in two independent laboratories using samples of peanuts and maize spiked at 2, 8, and 40 μg/kg total aflatoxins, and paprika, nutmeg, and dried figs spiked at 5, 20, and 100 μg/kg total aflatoxins. Recoveries exceeded 80% for both aflatoxin B1 and total aflatoxins. The between-day repeatability ranged from 2.1 to 9.6% for aflatoxin B1 for the six levels and five matrixes. Satisfactory Z-scores were obtained with this automated system when used for participation in proficiency testing (FAPAS®) for samples of chilli powder and hazelnut paste containing aflatoxins.

  19. The influence of sampling technique on ACT Plus results.

    Science.gov (United States)

    Brouwer, Monique E; Miraziz, Ramen; Agbulos, Grace; Steel, Rona; Hales, Peter; Klineberg, Peter

    2012-12-01

    The manufacturer of the ACT Plus Automated Coagulation Timer, Medtronic Inc., recommends that test cartridges be prewarmed and the activating reagent resuspended (tapped/ mixed) before patient testing. In a busy clinical environment, these recommendations may be overlooked or disregarded. In this study, the impact of sampling technique on ACT Plus test results was investigated. In Series 1, two test cartridges were split into four individual chambers. Two ACT Plus machines were used, allowing for three separate comparisons to be made. The sample results from test Chambers 2 (cold/tapped), 3 (warmed/ not tapped), and 4 (cold/not tapped) were compared individually against the result from test Chamber 1, the recommended technique (warm/tapped). In Series 2, the manufacturer's recommendations were tested using a single double cartridge (warm/ tapped). Results were interpreted using the Bland-Altman method of analysis. The prewarming and tapping of cartridges before use independently influenced the agreement of results when compared with cartridges that were not prewarmed and tapped. Each factor (temperature and mixing) when excluded was found to affect the standard deviation and decrease the agreement of results. By following the manufacturer's recommendations to standardize the sampling technique, ACT Plus test results are more accurate.

  20. A New Solid Phase Extraction for the Determination of Anthocyanins in Grapes

    Directory of Open Access Journals (Sweden)

    Marta Ferreiro-González

    2014-12-01

    Full Text Available A method for the concentration and cleaning of red grape extracts prior to the determination of anthocyanins by UPLC-DAD has been developed. This method is of special interest in the determination of phenolic maturity as it allows the analysis of the anthocyanins present in grapes. Several different SPE cartridges were assessed, including both C-18- and vinylbenzene-based cartridges. C-18-based cartridges presented a very low retention for the glucosylated anthocyanidins while vinylbenzene-based cartridges showed excellent retention for these compounds. The optimized method involves the initial conditioning of the cartridge using 10 mL of methanol and 10 mL of water, followed by loading of up to 100 mL of red grape extract. Ten mL of water was used in the washing step and anthocyanins were subsequently eluted using 1.5 mL of acidified methanol at pH 2. This method simplifies the determination of individual anthocyanins as, on the one hand, it cleans the sample of interference and, on the other hand, it increases the concentration to up to 25:1.5. The developed method has been validated with a range of different grapes and it has also been tested as a means of determining the different anthocyanins in grapes with different levels of maturity.

  1. Synthesis and Evaluation of Molecularly Imprinted Polymer for the Determination of the Phthalate Esters in the Bottled Beverages by HPLC

    Directory of Open Access Journals (Sweden)

    Ya-Feng Jin

    2013-01-01

    Full Text Available A molecularly imprinted polymer (MIP was prepared in acetonitrile by bulk polymerization, using di-n-octylphthalate (DOP as a template molecular, α-methacrylic acid (MAA as a functional monomer, and ethylene dimethacrylate (EDMA as a crosslinker. Characterization and evaluation of the prepared MIP were carried out by scanning electron microscope (SEM, infrared absorption spectroscopy (IR, and the Scatchard analysis, respectively. Through the optimization of washing solvent, eluting solvent amount, flow rate of loading solution, and loading sample volume, an analysis method was established for DOP related compounds with high selectivity and sensitivity by using the selective molecularly imprinted solid-phase extraction (MI-SPE technique. Moreover, under the optimal conditions, the extraction effects were comparatively investigated by using MIP cartridge, NIP cartridge, and the commercial PLS cartridge used especially for phthalic acid esters (PAEs, respectively. The results showed that the recoveries of spiked PAEs are in the range of 90.4%–97.8% with the relative standard deviation (RSD of 1.6%–3.8% on the resulted MIP cartridge, whilst lower recoveries were obtained ranging from 80.2% to 88.9% with an RSD of 1.4%–5.2% on the commercial PLS cartridge.

  2. Simple system for isothermal DNA amplification coupled to lateral flow detection.

    Directory of Open Access Journals (Sweden)

    Kristina Roskos

    Full Text Available Infectious disease diagnosis in point-of-care settings can be greatly improved through integrated, automated nucleic acid testing devices. We have developed an early prototype for a low-cost system which executes isothermal DNA amplification coupled to nucleic acid lateral flow (NALF detection in a mesofluidic cartridge attached to a portable instrument. Fluid handling inside the cartridge is facilitated through one-way passive valves, flexible pouches, and electrolysis-driven pumps, which promotes a compact and inexpensive instrument design. The closed-system disposable prevents workspace amplicon contamination. The cartridge design is based on standard scalable manufacturing techniques such as injection molding. Nucleic acid amplification occurs in a two-layer pouch that enables efficient heat transfer. We have demonstrated as proof of principle the amplification and detection of Mycobacterium tuberculosis (M.tb genomic DNA in the cartridge, using either Loop Mediated Amplification (LAMP or the Exponential Amplification Reaction (EXPAR, both coupled to NALF detection. We envision that a refined version of this cartridge, including upstream sample preparation coupled to amplification and detection, will enable fully-automated sample-in to answer-out infectious disease diagnosis in primary care settings of low-resource countries with high disease burden.

  3. DNA from fecal immunochemical test can replace stool for detection of colonic lesions using a microbiota-based model.

    Science.gov (United States)

    Baxter, Nielson T; Koumpouras, Charles C; Rogers, Mary A M; Ruffin, Mack T; Schloss, Patrick D

    2016-11-14

    There is a significant demand for colorectal cancer (CRC) screening methods that are noninvasive, inexpensive, and capable of accurately detecting early stage tumors. It has been shown that models based on the gut microbiota can complement the fecal occult blood test and fecal immunochemical test (FIT). However, a barrier to microbiota-based screening is the need to collect and store a patient's stool sample. Using stool samples collected from 404 patients, we tested whether the residual buffer containing resuspended feces in FIT cartridges could be used in place of intact stool samples. We found that the bacterial DNA isolated from FIT cartridges largely recapitulated the community structure and membership of patients' stool microbiota and that the abundance of bacteria associated with CRC were conserved. We also found that models for detecting CRC that were generated using bacterial abundances from FIT cartridges were equally predictive as models generated using bacterial abundances from stool. These findings demonstrate the potential for using residual buffer from FIT cartridges in place of stool for microbiota-based screening for CRC. This may reduce the need to collect and process separate stool samples and may facilitate combining FIT and microbiota-based biomarkers into a single test. Additionally, FIT cartridges could constitute a novel data source for studying the role of the microbiome in cancer and other diseases.

  4. Radiation effects on the dissolution kinetics of magnetite and hematite in EDTA- and NTA-based dilute chemical decontamination formulations

    Science.gov (United States)

    Keny, S. J.; Kumbhar, A. G.; Venkateswaran, G.; Kishore, Kamal

    2005-03-01

    Ethylene diamine tetraacetic acid (EDTA)- and nitrilo triacetic acid (NTA)-based formulations such as citric acid (CA)/EDTA/ascorbic acid (AA), CA/EDTA/gallic acid (GA), CA/NTA/AA and CA/NTA/GA were used for dissolving magnetite and hematite under similar experimental conditions of temperature, amount of the oxide and the concentration of the formulations (close to stoichiometric conditions). In unirradiated solutions, EDTA-based formulations were more efficient in dissolving these oxides than NTA-based formulations. Similarly, formulations containing AA as reductant gave better results as compared to formulations containing GA as reductant in unirradiated solutions. However, in gamma-irradiated formulations, the efficiency of dissolution was affected to a much greater extent in EDTA and AA containing formulations as compared to NTA and GA containing formulations. Both NTA and GA were found to be less prone to radiation degradation as compared to EDTA and AA.

  5. Effect of gamma-irradiated sludge on the growth and yield of rice (Oryza sativa L. var. GR-3).

    Science.gov (United States)

    Pandya, G A; Prakash, L; Devasia, P; Modi, V V

    1988-01-01

    The effects of gamma-irradiated sludge on the growth and yield of rice (Oryza sativa L. var. GR-3) in pot cultures have been studied. Compared to plants grown only in soil, shoot length, root length, fresh weight, dry weight, total proteins, total soluble sugars, starch and chlorophyll content of plants grown in soil supplemented with unirradiated or gamma-irradiated sludge were found to be significantly increased. Irradiation of sludge significantly stimulated the linear growth of shoot and root systems as well as fresh and dry weights of plants, compared to those grown in soil containing unirradiated sludge. There was also an improvement in the grain yield (weight of seed) when plants were grown in soil supplemented with irradiated sludge. The results obtained suggest that the gamma-irradiated sewage sludge can be beneficially recycled for agricultural uses.

  6. Effect of gas environment and sorbate addition on flavor characteristics of irradiated apple cider during storage.

    Science.gov (United States)

    Crook, Loretta R; Boylston, Terri D; Glatz, Bonita A

    2004-11-17

    Apple cider, with (0.1%) and without potassium sorbate, was packaged in polystyrene containers and exposed to three different gas environments: oxygen flush, nitrogen flush, and atmospheric air. To evaluate the effects of irradiation (2 kGy) and storage on flavor and microbial quality, these irradiated apple cider samples were compared to a control, unirradiated sample exposed to atmospheric air. Volatile compounds, soluble solids, titratable acidity, and microbiological counts were determined weekly throughout 7 weeks of refrigerated (4 degrees C) storage. Cider irradiated and stored in atmospheric air or nitrogen-flush environments had lower rates of loss for characteristic flavor volatiles compared to unirradiated apple cider and cider irradiated and stored in an oxygen-flush environment. The addition of potassium sorbate to the apple cider resulted in lower counts of yeasts and aerobic microorganisms, reduced fermentation of sugars to organic acids, and improved retention of volatile compounds characteristic of apple cider.

  7. In vivo UVB irradiation induces clustering of Fas (CD95) on human epidermal cells

    DEFF Research Database (Denmark)

    Bang, Bo; Gniadecki, Robert; Larsen, Jørgen K

    2003-01-01

    a single dose of UVB irradiation. Normal healthy individuals were irradiated with three minimal erythema doses (MED) of UVB on forearm or buttock skin. Suction blisters from unirradiated and irradiated skin were raised, and Fas, FasL, and apoptosis of epidermal cells quantified by flow cytometry....... Clustering of Fas was from skin biopsied. Soluble FasL in suction blister fluid was quantified by ELISA. Flow cytometric analysis demonstrated increased expression intensity of Fas after irradiation, with 1.6-,2.2- and 2.7-fold increased median expression at 24, 48 and 72 h after irradiation, respectively (n...... of soluble FasL in suction blister fluid from UVB-irradiated skin did not differ from those in unirradiated skin (n=5). Confocal laser scanning microscopy showed a rapid clustering of Fas within 30 min after irradiation. A simultaneous clustering of the adapter signalling protein FADD suggested that Fas...

  8. Proton irradiation studies on Al and Al5083 alloy

    Science.gov (United States)

    Bhattacharyya, P.; Gayathri, N.; Bhattacharya, M.; Gupta, A. Dutta; Sarkar, Apu; Dhar, S.; Mitra, M. K.; Mukherjee, P.

    2017-10-01

    The change in the microstructural parameters and microhardness values in 6.5 MeV proton irradiated pure Al and Al5083 alloy samples have been evaluated using different model based techniques of X-ray diffraction Line Profile Analysis (XRD) and microindendation techniques. The detailed line profile analysis of the XRD data showed that the domain size increases and saturates with irradiation dose both in the case of Al and Al5083 alloy. The corresponding microstrain values did not show any change with irradiation dose in the case of the pure Al but showed an increase at higher irradiation doses in the case of Al5083 alloy. The microindendation results showed that unirradiated Al5083 alloy has higher hardness value compared to that of unirradiated pure Al. The hardness increased marginally with irradiation dose in the case of Al5083, whereas for pure Al, there was no significant change with dose.

  9. Effects of irradiated biodegradable polymer in endothelial cell monolayer formation

    Energy Technology Data Exchange (ETDEWEB)

    Arbeitman, Claudia R.; Grosso, Mariela F. del [CONICET – Consejo Nacional de Investigaciones Científicas y Técnicas (Argentina); Gerencia de Investigación y Aplicaciones, TANDAR-CNEA (Argentina); Behar, Moni [Instituto de Física, UFRGS, Porto Alegre, RS (Brazil); García Bermúdez, Gerardo, E-mail: ggb@tandar.cnea.gov.ar [CONICET – Consejo Nacional de Investigaciones Científicas y Técnicas (Argentina); Gerencia de Investigación y Aplicaciones, TANDAR-CNEA (Argentina); Escuela de Ciencia y Tecnología, UNSAM (Argentina)

    2013-11-01

    In this work we study cell adhesion, proliferation and cell morphology of endothelial cell cultured on poly-L-lactide acid (PLLA) modified by heavy ion irradiation. Thin films of PLLA samples were irradiated with sulfur (S) at energies of 75 MeV and gold (Au) at 18 MeV ion-beams. Ion beams were provided by the Tandar (Buenos Aires, Argentina) and Tandetron (Porto Alegre, Brazil) accelerators, respectively. The growth of a monolayer of bovine aortic endothelial cells (BAEC) onto unirradiated and irradiated surfaces has been studied by in vitro techniques in static culture. Cell viability and proliferation increased on modified substrates. But the results on unirradiated samples, indicate cell death (necrosis/apoptosis) with the consequent decrease in proliferation. We analyzed the correlation between irradiation parameters and cell metabolism and morphology.

  10. THE KFIB EXPERIMENT

    Energy Technology Data Exchange (ETDEWEB)

    Youngblood, Gerald E.; Senor, David J.; Jones, Russell H.; Kowbel, W.; Kohyama, A.

    2000-06-30

    Several rod-shaped specimens with uniaxially packed fibers (Hi-Nicalon™, Hi-Nicalon™ Type S, Tyranno™ SA and Amoco K1100™ types) in a pre-ceramic polymer matrix were fabricated. By using appropriate analytic models, the bare fiber thermal conductivity (Kf) will be determined as a function of temperature up to 1000°C before and after irradiation for samples cut from these rods. Preliminary thermal conductivity data for unirradiated fibers (Hi-Nicalon™ and Tyranno™ SA-B SiC and K1100™ graphite) and for three types of unirradiated composites made from these fibers (2D-Nicalon S/SiC multilayer/CVI-SiC, 3D-Nicalon S/PIP-SiC, and 2D-8HS Tyrannohex™ HP) are presented.

  11. The radiation swelling effect on fracture properties and fracture mechanisms of irradiated austenitic steels. Part II. Fatigue crack growth rate

    Science.gov (United States)

    Margolin, B.; Minkin, A.; Smirnov, V.; Sorokin, A.; Shvetsova, V.; Potapova, V.

    2016-11-01

    The experimental data on the fatigue crack growth rate (FCGR) have been obtained for austenitic steel of 18Cr-10Ni-Ti grade (Russian analog of AISI 321 steel) irradiated up to neutron dose of 150 dpa with various radiation swelling. The performed study of the fracture mechanisms for cracked specimens under cyclic loading has explained why radiation swelling affects weakly FCGR unlike its effect on fracture toughness. Mechanical modeling of fatigue crack growth has been carried out and the dependencies for prediction of FCGR in irradiated austenitic steel with and with no swelling are proposed and verified with the obtained experimental results. As input data for these dependencies, FCGR for unirradiated steel and the tensile mechanical properties for unirradiated and irradiated steels are used.

  12. Dearomatization of jet fuel on irradiated platinum-supported catalyst

    Science.gov (United States)

    Múčka, V.; Ostrihoňová, A.; Kopernický, I.; Mikula, O.

    The effect of ionizing radiation ( 60Co γ-rays) on Pt-supported catalyst used for the dearomatization of jet fuel with distillation in the range 395-534 K has been studied. Pre-irradiation of the catalyst with doses in the range 10 2-5 × 10 4 Gy leads to the partial catalyst activation. Irradiation of the catalyst enhances its resistance to catalyst poisons, particularly to sulphur-compounds, and this is probably the reason for its catalytic activity being ˜60-100% greater than that of un-irradiated catalyst. Optimum conditions for dearomatization on the irradiated catalyst were found and, by means of a rotary three-factorial experiment, it was shown that these lie at lower temperatures and lower pressures than those for un-irradiated catalyst.

  13. Thermal analysis applied to irradiated propolis

    Science.gov (United States)

    Matsuda, Andrea Harumi; Machado, Luci Brocardo; del Mastro, Nélida Lucia

    2002-03-01

    Propolis is a resinous hive product, collected by bees. Raw propolis requires a decontamination procedure and irradiation appears as a promising technique for this purpose. The valuable properties of propolis for food and pharmaceutical industries have led to increasing interest in its technological behavior. Thermal analysis is a chemical analysis that gives information about changes on heating of great importance for technological applications. Ground propolis samples were 60Co gamma irradiated with 0 and 10 kGy. Thermogravimetry curves shown a similar multi-stage decomposition pattern for both irradiated and unirradiated samples up to 600°C. Similarly, through differential scanning calorimetry , a coincidence of melting point of irradiated and unirradiated samples was found. The results suggest that the irradiation process do not interfere on the thermal properties of propolis when irradiated up to 10 kGy.

  14. Ageing Tests of Radiation Damaged Lasers and Photodiodes for the CMS Tracker Optical Links

    CERN Document Server

    Gill, K; Batten, J; Cervelli, G; Grabit, R; Jensen, F; Troska, Jan K; Vasey, F

    1999-01-01

    The effects of thermally accelerated ageing in irradiated and unirradiated 1310nm InGaAsP edge-emitting lasers and InGaAs p-i-n photodiodes are presented. 40 lasers ( 20 irradiated) and 30 photodiodes ( 19 irradiated) were aged for 4000 hours at 80¡C. Periodic measurements were made of laser threshold and efficiency, and p-i-n leakage current and photocurrent. There were no sudden failures and there was very little wearout related degradation in either unirradiated or irradiated sample groups. The results suggest that the tested devices have a sufficiently long lifetime to operate for at least 10 years inside the CMS Tracker despite being exposed to a harsh radiation environment.

  15. In vivo mutagenicity studies in rats mice and Chinese hamsters fed irradiated foodstuffs - chicken, fish, dates, pulses, mangoes and cocoa beans

    Energy Technology Data Exchange (ETDEWEB)

    Renner, H.W.

    1982-11-01

    Three in vivo genetic toxicity tests were performed in rats, mice and Chinese hamsters to detect possible mutagenic effects of irradiated chicken, dried dates, fish, cocoa beans, pulses and mangoes. The tests employed were the micronucleus test and sister-chromatid exchange (SCE) test for irradiated and unirradiated samples of all foodstuffs listed, and the spermatogonia test, (including SCE technique) in mice for irradiated and unirradiated chicken, fish and dates only. In the case of cocoa beans, the mutagenicity tests were performed on an additional test group fed beans fumigated with ethylene oxide. The different mammalian species used for the various experiments are given below. None of the tests provided any evidence of mutagenicity induced by irradiation in any of the foodstuffs studied. Moreover, these tests are currently considered to be the most sensitive in vivo mutagenicity tests in mammals.

  16. High thermal conductivity SiC/SiC composites for fusion applications -- 2

    Energy Technology Data Exchange (ETDEWEB)

    Kowbel, W.; Tsou, K.T.; Withers, J.C. [MER Corp., Tucson, AZ (United States); Youngblood, G.E. [Pacific Northwest National Lab., Richland, WA (United States)

    1998-03-01

    This report covers material presented at the IEA/Jupiter Joint International Workshop on SiC/SiC Composites for Fusion Structural Applications held in conjunction with ICFRM-8, Sendai, Japan, Oct. 23--24, 1997. An unirradiated SiC/SiC composite made with MER-developed CVR SiC fiber and a hybrid PIP/CVI SiC matrix exhibited room temperature transverse thermal conductivity of 45 W/mK. An unirradiated SiC/SiC composite made from C/C composite totally CVR-converted to a SiC/SiC composite exhibited transverse thermal conductivity values of 75 and 35 W/mK at 25 and 1000 C, respectively. Both types of SiC/SiC composites exhibited non-brittle failure in flexure testing.

  17. Dyeing of UV irradiated cotton and polyester fabrics with multifunctional reactive and disperse dyes

    Directory of Open Access Journals (Sweden)

    Ijaz Ahmad Bhatti

    2016-03-01

    Full Text Available The dyeing behaviour of UV irradiated cotton and polyester fabrics using multifunctional reactive and disperse dyes has been investigated. The plain, woven, mercerized, bleached, cotton and polyester fabrics were exposed to UV radiation (180 w, 254 nm for 30, 60, 90 and 120 min. Dyeing was performed using irradiated fabric with a dye solution of un-irradiated reactive and disperse/azo dyes. The dyeing parameters such as, temperature, time, pH and salt concentration have been optimized. The colour strength values of dyed fabrics were evaluated by comparing irradiated and un-irradiated cotton and polyester fabrics in CIE Lab systems using spectra flash SF600. Finally ISO standard methods were employed to observe the effect of UV radiation on fastness properties. It was found that UV radiation has a potential to improve the colour strength values of cotton and polyester fabrics by using reactive and disperse dyes.

  18. Improvement of colour strength and colourfastness properties of gamma irradiated cotton using reactive black-5

    Science.gov (United States)

    Ahmad Bhatti, Ijaz; Adeel, Shahid; Nadeem, Raziya; Asghar, Toheed

    2012-03-01

    The dyeing behaviour of gamma irradiated cotton fabric using Reactive Black-5 dye powder has been investigated. The mercerized, bleached and plain weaved cotton fabric was irradiated to different absorbed doses of 100, 200, 300, 400, 500 and 600 Gy using Co-60 gamma irradiator. Dyeing was performed using irradiated and un-irradiated cotton with dye solutions. The dyeing parameters such as temperature of dyeing, time of dyeing and pH of dyeing solutions were optimised. The colour strength values of dyed fabrics were evaluated by comparing irradiated and un-irradiated cotton in CIE Lab system using Spectra flash SF650. Methods suggested by International Standard Organisation (ISO) were employed to study the effect of gamma irradiation on the colourfastness properties of dyed fabric. It is found that gamma irradiated cotton dyed with Reactive Black-5 has not only improved the colour strength but also enhanced the rating of fastness properties.

  19. Effect of mercerization and gamma irradiation on the dyeing behaviour of cotton using stilbene based direct dye

    Science.gov (United States)

    Bhatti, Ijaz Ahmad; Adeel, Shahid; Fazal-ur-Rehman; Irshad, Misbah; Abbas, Muhammad

    2012-07-01

    The dyeing behaviour of mercerized and gamma irradiated cotton fabric using stilbene based direct dye has been investigated. The fabric was treated with different concentrations of alkali to optimize the mercerization. The optimum mercerized cotton fabric was irradiated to absorbed doses of 2, 4, 6, 8 and 10 kGy using Cs-137 gamma irradiator. Dyeing was performed using irradiated and un-irradiated cotton with dye solutions. The dyeing parameters such as temperature, time of dyeing, pH of dyeing solutions and salt concentration were optimized. The colour strength values of dyed fabrics were evaluated by comparing irradiated and un-irradiated cotton in CIE Lab system using Spectra flash SF650. Methods suggested by International Standard Organization (ISO) were employed to study the effect of gamma irradiation on the colourfastness properties of dyed fabric. It was found that mercerized and irradiated cotton have not only improved the colour strength but enhanced the rating of fastness properties also.

  20. Electron beam irradiated HDPE/EVA/Mg(OH)2 composites for flame-retardant electric cables

    Institute of Scientific and Technical Information of China (English)

    Hui LIU; Nabil A. Noman ALKADASI; Yan ZHU; Li-fang TONG; Zheng-ping FANG; Yong-chang WANG

    2008-01-01

    The mechanical properties and flammability of high-density polyethylene (HDPE)/ethylene vinyl acetate (EVA) mixed with various amounts of magnesium hydroxide (Mg(OH)2) as the filler in composites, irra-diated with electron beam at an irradiation dose of 150 kGy, have been studied. It is found that high-energy electron beam irradiation has significant effects on the mechanical properties of the HDPE/EVA/Mg(OH)2 com-posites. The tensile strength and elastic modulus increased greater than in the unirradiated ones. Meanwhile, with increasing the content of Mg(OH)2 in the composites, the limiting oxygen index (LOI) value increased sharply. The microstructure of the caves of the unirradiated HDPE/EVA/Mg(OH)2 composites show poor interface of composites compared with the irradiated ones, as observed in SEM micrographs.

  1. Thermal analysis applied to irradiated propolis

    Energy Technology Data Exchange (ETDEWEB)

    Matsuda, Andrea Harumi; Machado, Luci Brocardo; Mastro, N.L. del E-mail: nelida@usp.br

    2002-03-01

    Propolis is a resinous hive product, collected by bees. Raw propolis requires a decontamination procedure and irradiation appears as a promising technique for this purpose. The valuable properties of propolis for food and pharmaceutical industries have led to increasing interest in its technological behavior. Thermal analysis is a chemical analysis that gives information about changes on heating of great importance for technological applications. Ground propolis samples were {sup 60}Co gamma irradiated with 0 and 10 kGy. Thermogravimetry curves shown a similar multi-stage decomposition pattern for both irradiated and unirradiated samples up to 600 deg. C. Similarly, through differential scanning calorimetry , a coincidence of melting point of irradiated and unirradiated samples was found. The results suggest that the irradiation process do not interfere on the thermal properties of propolis when irradiated up to 10 kGy.

  2. Irradiation detection of coffee mate by electron spin resonance (ESR)

    Science.gov (United States)

    Özsayin, Fulya; Polat, Mustafa

    2011-06-01

    Un-irradiated coffee mate samples do not exhibit any ESR signal. However, the samples exposed to UV and gamma radiation exhibit an ESR singlet and a large unresolved ESR signal, respectively. The dose-response curves of the samples exposed to UV and gamma radiations were found to be described well by an exponential and linear functions, respectively. Variable temperature and fading studies at room temperature showed that the radiation-induced radicals in coffee mate sample are very sensitive to temperature. The discrimination between un-irradiated and irradiated coffee mate samples can be done just comparing their ESR spectra. However, determination of the radiation dose received by the sample cannot be possible because of the fast decay of signal intensity at room temperature.

  3. Identification and dose assessment of irradiated cardamom and cloves by EPR spectrometry

    Science.gov (United States)

    Beshir, W. B.

    2014-03-01

    The use of electron paramagnetic resonance spectroscopy to accurately distinguish irradiated from unirradiated cardamom and cloves and assesses the absorbed dose to radiation processed cardamom and cloves are examined. The results were successful for identifying both irradiated and unirradiated cardamom and cloves. Additive reirradiation of cardamom and cloves produces reproducible dose-response functions, which can be used to assess the initial dose by back-extrapolation. Third degree polynomial function was used to fit the EPR signal/dose curves. It was found that this 3rd degree polynomial function provides satisfactory results without correction of decay for free radicals. The stability of the radiation induced EPR signal of irradiated cardamom and cloves were studied over a storage period of almost 8 months.

  4. Ageing tests of radiation damaged lasers and photodiodes for the CMS experiment at CERN

    CERN Document Server

    Gill, K; Batten, J; Cervelli, G; Grabit, R; Jensen, F; Troska, Jan K; Vasey, F

    2000-01-01

    The effects of thermally accelerated ageing in irradiated and unirradiated 1310 nm InGaAsP edge-emitting lasers and InGaAs p-i-n photodiodes are presented. 40 lasers (20 irradiated) and 30 photodiodes (19 irradiated) were aged for 4000 hours at 80 degrees C. Periodic measurements were made of laser threshold and efficiency, and p-i-n leakage current and photocurrent. There were no sudden failures and there was very little wearout related degradation in either unirradiated or irradiated sample groups. The results suggest that the tested devices have a sufficiently long lifetime to operate for at least 10 years inside the Compact Muon Solenoid experiment despite being exposed to a harsh radiation environment. (19 refs).

  5. Effect of ultrasonic irradiation on mammalian cells and chromosomes in vitro

    Science.gov (United States)

    Roseboro, J. A.; Buchanan, P.; Norman, A.; Stern, R.

    1978-01-01

    Human peripheral blood and HeLa cells were irradiated in vitro at the ultrasonic frequency of 65 kHz. The whole blood and HeLa cell suspensions were exposed to continuous and pulsed ultrasonic power levels of 0.12, 0.16, 0.72, 1.12 and 2.24 W for a period of one minute. The method of ultrasonic irradiation was carried out with the whole blood or HeLa cell suspensions coupled directly to a cylindrical transducer while heating of the cell suspensions in excess of 41 C was avoided. Irradiated and unirradiated peripheral blood lymphocyte chromosome cultures were prepared and scored for selected numerical and morphological aberrations. There was no significant difference in the frequency of chromosomal aberrations between irradiated and unirradiated cells.

  6. The freezing and thawing of water in poultry meat and vegetables irradiated by electrons at doses of 0.1-4 kGy.

    Science.gov (United States)

    Dubini, B; Ferrante, L; Leonardi, M; Messina, G; Montecchia, F; Ponzi-Bossi, M G

    1993-06-01

    Poultry meat and some vegetables, irradiated by 5 MeV electrons (0.1-4 kGy), were analysed by differential scanning calorimetry, from 24 h after irradiation. The temperature and enthalpy transitions of the water contained in the irradiated samples were measured and compared with those of unirradiated samples. We analysed 18 meat and 10 vegetable samples for each irradiation dose together with a similar number of unirradiated controls. The mean supercooling temperatures of water in the irradiated poultry meat samples and in some vegetables are significantly lower than those of controls. Moreover, the freezing enthalpies of the irradiated poultry breast are significantly lower than those of controls, while they are unchanged in the other cases. The mean ice melting temperatures and enthalpies are similar for all samples. The amount of the lowering of the water-ice transition depends on the nature of the sample and is highest in poultry breast and lowest in vegetables.

  7. Study of dose-response and radical decay curves of gamma irradiated norfloxacin using EPR spectroscopy

    Science.gov (United States)

    Sütçü, Kerem; Osmanoǧlu, Yunus Emre

    2017-02-01

    In this study, Electron Paramagnetic Resonance (EPR) spectra of unirradiated and γ-irradiated at doses of 1, 5, 10, 12 and 15 kGy norfloxacin (NOF) were investigated. Before irradiation no EPR signal were observed. After irradiation a weak singlet signal at g = 2.0039 were obtained at room temperature. In order to describe the variation of EPR signal intensity with absorbed radiation dose, several mathematical equations were tried. Increasing irradiation dose up to 15 kGy has increased the signal intensity of the central signal however, no significant changes were observed in g spectroscopic splitting factor. The stability of signal intensity of irradiated NOF was studied over a storage period of 200 days. According to analyses conducted, EPR spectroscopy can be used to distinguish irradiated and unirradiated samples from each other.

  8. Nuclear Terrorism: Assessing the Threat, Developing a Response

    Science.gov (United States)

    2009-01-01

    separated plutonium might be found at civilian reprocessing facilities or mixed oxide ( MOX ) fuel fabrication plants, but this material would likely be in...2008. 165 Potter and Ferguson, The Four Faces of Nuclear Terrorism, p. 121. MOX reactor fuel contains approxi- mately four to seven percent...stealing spent power reactor fuel or fresh (unirradiated) MOX fuel, both of which would need to have their plutonium chemically extracted. While separating

  9. Quantitative analysis of hydrogen gas formed by aqueous corrosion of metallic uranium

    Energy Technology Data Exchange (ETDEWEB)

    Fonnesbeck, J.

    2000-03-20

    Three unirradiated EBR-II blanket fuel samples containing depleted uranium metal were corrosion tested in simulated J-13 well water at 90 C. The corrosion rate of the blanket uranium metal was then determined relative to H{sub 2} formation. Corrosion of one of the samples was interrupted prior to complete oxidation of the uranium metal and the solid corrosion product was analyzed for UO{sub 2} and UH{sub 3}.

  10. Silicon sensor technologies for the ATLAS IBL upgrade.

    CERN Document Server

    Grenier, P

    2012-01-01

    An overview of radiation hard planar and 3D pixel sensor technologies currently under development for ATLAS upgrades is presented. The first upgrade will be the installation in 2013 of an additional pixel layer inside the current inner detector, the Insertable B Layer (IBL). The two technologies are competing to equip the IBL. The IBL sensor qualification procedure is described. Beam test results of un-irradiated and irradiated planar and 3D sensors are presented.

  11. Radiation Hard Silicon Photonics Mach-Zehnder Modulator for HEP applications: all-Synopsys Sentaurus™ Pre-Irradiation Simulation

    CERN Document Server

    Cammarata, Simone

    2017-01-01

    Silicon Photonics may well provide the opportunity for new levels of integration between detectors and their readout electronics. This technology is thus being evaluated at CERN in order to assess its suitability for use in particle physics experiments. In order to check the agreement with measurements and the validity of previous device simulations, a pure Synopsys Sentaurus™ simulation of an un-irradiated Mach-Zehnder silicon modulator has been carried out during the Summer Student project.

  12. An autonomic self-healing organogel with a photo-mediated modulus

    KAUST Repository

    Xiong, Yubing

    2016-11-15

    A new method is described for fabricating autonomic, self-healing, deformable organogels. We combined imidazolium-based poly(ionic liquid) (PIL) and azobenzene-grafted poly(carboxylic acid) (PAA-Azo) in N,N-dimethyl formamide. Further, complexing PIL with unirradiated (trans) or irradiated (cis) PAA-Azo tuned the elastic modulus of the organogel. © 2016 The Royal Society of Chemistry.

  13. Radiation induced chemical changes of phenolic compounds in strawberries

    Energy Technology Data Exchange (ETDEWEB)

    Breitfellner, F.; Solar, S. E-mail: sonja.solar@univie.ac.at; Sontag, G

    2003-06-01

    In unirradiated strawberries four phenolic acids (gallic acid, p-coumaric acid, caffeic acid and 4-hydroxybenzoic acid), the flavonoids (+)-catechin, (-)-epicatechin and glycosides from kaempferol and quercetin were determined by reversed phase chromatography with diode array detection. Characteristic linear dose/concentration relationships were found for 4-hydroxybenzoic acid and two unidentified compounds. One of them may be usable as marker to prove an irradiation treatment.

  14. Bystander effect in human hepatoma HepG2 cells caused by medium transfers at different times after high-LET carbon ion irradiation

    Science.gov (United States)

    Wu, Qingfeng; Li, Qiang; Jin, Xiaodong; Liu, Xinguo; Dai, Zhongying

    2011-01-01

    Although radiation-induced bystander effects have been well documented in a variety of biological systems, whether irradiated cells have the ability to generate bystander signaling persistently is still unclear and the clinical relevance of bystander effects in radiotherapy remains to be elucidated. This study examines tumor cellular bystander response to autologous medium from cell culture irradiated with high-linear energy transfer (LET) heavy ions at a therapeutically relevant dose in terms of clonogenic cell survival. In vitro experiments were performed using human hepatoma HepG2 cell line exposed to 100 keV/μm carbon ions at a dose of 2 Gy. Two different periods (2 and 12 h) after irradiation, irradiated cell conditioned medium (ICCM) and replenished fresh medium were harvested and then transferred to unirradiated bystander cells. Cellular bystander responses were measured with the different medium transfer protocols. Significant higher survival fractions of unirradiated cells receiving the media from the irradiated cultures at the different times post-irradiation than those of the control were observed. Even replenishing fresh medium for unirradiated cells which had been exposed to the ICCM for 12 h could not prevent the bystander cells from the increased survival fraction. These results suggest that the irradiated cells could release unidentified signal factor(s), which induced the increase in survival fraction for the unirradiated bystander cells, into the media sustainedly and the carbon ions triggered a cascade of signaling events in the irradiated cells rather than secreting the soluble signal factor(s) just at a short period after irradiation. Based on the observations in this study, the importance of bystander effect in clinical radiotherapy was discussed and incorporating the bystander effect into the current radiobiological models, which are applicable to heavy ion radiotherapy, is needed urgently.

  15. Investigation of physical detection markers in irradiated foods under different radiation sources and post-irradiation storage conditions

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, Joong Ho; Kim, Gui Ran; Ahn, Jae Jun; Kim, Dong Gil; Jin, Qiong Wen; Park, Ju Hwan; Lee, Ji Hyun [Kyungpook National University, Daegu (Korea, Republic of)

    2010-04-15

    In PSL analysis, all unirradiated samples showed less than 700 (negative) photon counts (PCs). At 5 kGy, spice samples showed PCs in range of 700-5,000 (intermediate), while grains, legumes, root-crops, and seasonings samples showed PCs over 5,000 (positive). This PSL based-detection of radiation treatment was possible even after 24 months of storage. In TL analysis, TL glow curve was characteristically different between unirradiated and irradiated samples. Glow curves were observed in temperature ranges of 150-250 .deg. C for irradiated and over 300 .deg. C for unirradiated samples. TL ratio (TL{sub 1}/TL{sub 2}) provided valuable additional confirmations as unirradiated sample showed values less than 0.1, while irradiated sample showed more than 0.1. However, with storage time, TL intensity and TL ratio decreased but discrimination was still possible even after storage of 24 months. Samples stored at room temperature with exposure to direct or indirect light enhanced the mentioned decrease of TL intensity and TL ratio as compared to low temperature storage in dark room. In ESR analysis, legumes and spices showed radiation-induced cellulose radicals, while seasonings showed multi-component signals of radiation-induced crystalline sugar radical. These radiation-induced radicals could be potential markers for the detection of radiation treatments in subjected samples. The decreasing trend was also found for radiation-specific ESR signals of cellulose and crystalline sugar radicals during storage. However, radiation-induced radicals in legumes, powdered pepper and seasonings were detectable even after 6 months of storage

  16. Nephropathy in the mature pig after the irradiation of a single kidney: A comparison with the immature pig

    Energy Technology Data Exchange (ETDEWEB)

    Robbins, M.E.; Campling, D.; Rezvani, M.; Golding, S.J.; Hopewell, J.W.

    1989-06-01

    The right kidney of 11 mature 10-month-old Large White female pigs was irradiated with single doses of 9.8-14.0 Gy of 60Co gamma rays. Individual kidney glomerular filtration rate (GFR) and effective renal plasma flow (ERPF) were measured using 99mTc-DTPA and 131I-hippuran renography for periods up to 24 weeks after irradiation. Renal function was assessed either as a functional index, FI (FI = irradiated/unirradiated kidney function), or as the individual kidney GFR and ERPF. The radiation-induced changes after the irradiation of a single kidney (unilaterally irradiated--UI) of mature pigs were compared with those previously observed in 14-week-old immature pigs. Irradiation resulted in a dose-dependent reduction in the FI for both GFR and ERPF. However, these reductions were significantly less than those previously seen in immature pigs. Within 2 weeks of irradiation GFR increased in both the irradiated and the unirradiated kidneys in each animal, compared with unirradiated age-matched control kidneys. No marked changes in renal hemodynamics were seen in mature animals after a single dose of 9.8 Gy. This was in marked contrast to the pronounced reduction in the GFR and ERPF in the irradiated kidney previously observed in immature animals irradiated with an equivalent single dose of X rays. After higher doses, the irradiated kidney in mature pigs showed a dose-dependent reduction in GFR and ERPF. However, the extent of this reduction was significantly less than that seen in immature animals. There was no apparent difference in the response of the unirradiated kidneys in mature or immature pigs. The ED50 values, based on a probit fit to the data for the proportion of functional tests in which the irradiated kidney showed a greater than or equal to 50% reduction in GFR or ERPF, were higher in the mature animals.

  17. Thorium utilization program. Quarterly progress report for the period ending May 31, 1976. [Fuel element crushing, solids handling, fluidized-bed combustion, aqueous separations, solvent extraction, off-gas studies, semiremote handling systems, alternative head-end processing, and fuel recycle design

    Energy Technology Data Exchange (ETDEWEB)

    1976-06-30

    The work reported includes the development of unit processes and equipment for reprocessing of High-Temperature Gas-Cooled Reactor (HTGR) fuel and the design and development of an integrated line to demonstrate the head end of HTGR reprocessing using unirradiated fuel materials. Work is also described on trade-off studies concerning the required design of recycle facilities for the large-scale recycle of HTGR fuels in order to guide the development activities for HTGR fuel recycle.

  18. Safety evaluation for packaging (onsite) disposable solid waste cask

    Energy Technology Data Exchange (ETDEWEB)

    Flanagan, B.D., Westinghouse Hanford

    1996-12-20

    This safety evaluation for packaging (SEP) evaluates and documents the ability of the Disposable Solid Waste Cask (DSWC) to meet the packaging requirements of HNF-CM-2-14, Hazardous Material Packaging and Shipping, for the onsite transfer of special form, highway route controlled quantity, Type B fissile radioactive material. This SEP evaluates five shipments of DSWCs used for the transport and storage of Fast Flux Test Facility unirradiated fuel to the Plutonium Finishing Plant Protected Area.

  19. French investigations of high burnup effect on LOCA thermomecanical behavior. Part two. Oxidation and quenching experiments under simulated LOCA conditions with high burnup clad material

    Energy Technology Data Exchange (ETDEWEB)

    GrandJean, C. [IPSN, Cadarache (France); Cauvin, R.; Lebuffe, C. [EDF/SCMI, Chinon (France)] [and others

    1997-01-01

    In the frame of the high burnup fuel studies to support a possible extension of the current discharge burnup limit, experimental programs have been undertaken, jointly by EDF and IPSN in order to study the thermal-shock behavior of high burnup fuel claddings under typical LOCA conditions. The TAGUS program used unirradiated cladding samples, bare or bearing a pre-corrosion state simulating the end-of-life state of high burnup fuel claddings: the TAGCIR program used actually irradiated cladding samples taken from high burnup rods irradiated over 5 cycles in a commercial EDF PWR and having reached a rod burnup close to 60 GWd/tU. The thermal-shock failure tests consisted in oxidizing the cladding samples under steam flow, on both inner and outer faces or on the outer face alone, and subjecting them to a final water quench. The heating was provided by an inductive furnace the power of which being regulated through monitoring of the sample surface temperature with use of a single-wave optical pyrometer. Analysis of the irradiated tests (TAGCIR series) evidenced an increased oxidation rate as compared to similar tests on unirradiated samples. Results of the quenching tests series on unirradiated and irradiated samples are plotted under the usual presentation of failure maps relative to the oxidation parameters ECR (equivalent cladding reacted) or e{sub {beta}} (thickness of the remaining beta phase layer) as a function of the oxidation temperature. Comparison of the failure limits for irradiated specimens to those for unirradiated specimens indicates a lower brittleness under two side oxidation and possibly the opposite under one-side oxidation. The tentative analysis of the oxidation and quenching tests results on irradiated samples reveals the important role played by the hydrogen charged during in-reactor corrosion on the oxidation kinetics and the failure bearing capability of the cladding under LOCA transient conditions.

  20. Fracture toughness of irradiated modified 9Cr-lMo steel

    Energy Technology Data Exchange (ETDEWEB)

    Kim, S.H.; Yoon, J.H.; Ryu, W.S.; Lee, C.B. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Hong, J.H. [KAERI - Korea Atomic Energy Research Institute, Nuclear Materials Technology Development Div., Daejon (Korea, Republic of)

    2007-07-01

    Full text of publication follows: Ferritic/martensitic steels have been used for a long time in the power generation industry as boiler and turbine materials. These steels are the proposed candidates for the crosscutting materials of the advanced nuclear power system. It is important to realize the change of mechanical properties by neutron irradiation for application these materials to nuclear power system. Irradiation effect on the fracture toughness of the structural materials is one of the concerns for the designing of the fusion devices. The test material was a 16 mm thick commercial Modified 9Cr-1Mo plate which was normalized at 1050 deg. C and tempered at 770 deg. C. The half sized pre-cracked Charpy specimens were irradiated at CT test hole in HANARO. Irradiation test was conducted at 340 deg. C and 400 deg. C to investigate the irradiation temperature effect on the degradation of the fracture toughness. And the irradiation fluence was 1.2x10{sup 21} n/cm{sup 2} (E>0.1 MeV). Toughness tests for the irradiated specimens will be performed in the hot cell at KAERI. The fracture toughness of the unirradiated condition was carried out in order to assess the changes in the materials properties caused by neutron irradiation. The K{sub JC} values in accordance at the ASTM E1921- 05 standard were obtained by three-point bending tests. Tests have been carried out at several temperatures within transition region. The multi-temperature method was used to determine reference temperature, T{sub o}. The applicability of the Master Curve method for irradiated and unirradiated ferritic/martensitic steel is another focus of this study. The reference temperature of the unirradiated specimen was -72.4 deg. C. And the Master Curve successfully expressed the trend of the fracture toughness change with temperature for unirradiated Modified 9Cr-1Mo steel. (authors)

  1. Electrical Characteristics of Silicon Pixel Sensors

    CERN Document Server

    Gorelov, I; Hoeferkamp, M; Mata-Bruni, V; Santistevan, G; Seidel, S C; Ciocio, A; Einsweiler, K F; Emes, J; Gilchriese, M G D; Joshi, A; Kleinfelder, S A; Marchesini, R; McCormack, F; Milgrome, O; Palaio, N; Pengg, F; Richardson, J; Zizka, G; Ackers, M; Comes, G; Fischer, P; Keil, M; Klasen, V; Kühl, T; Meuser, S; Ockenfels, W; Raith, B; Treis, J; Wermes, N; Gössling, C; Hügging, F G; Klaiber Lodewigs, Jonas M; Krasel, O; Wüstenfeld, J; Wunstorf, R; Barberis, D; Beccherle, R; Caso, Carlo; Cervetto, M; Darbo, G; Gagliardi, G; Gemme, C; Morettini, P; Netchaeva, P; Osculati, B; Rossi, L; Charles, E; Fasching, D; Blanquart, L; Breugnon, P; Calvet, D; Clemens, J-C; Delpierre, P A; Hallewell, G D; Laugier, D; Mouthuy, T; Rozanov, A; Valin, I; Andreazza, A; Caccia, M; Citterio, M; Lari, T; Meroni, C; Ragusa, F; Troncon, C; Vegni, G; Lutz, Gerhard; Richter, R H; Rohe, T; Boyd, GR; Skubic, P L; Sícho, P; Tomasek, L; Vrba, V; Holder, M; Ziolkowski, M; Cauz, D; Cobal-Grassmann, M; D'Auria, S; De Lotto, B; del Papa, C; Grassmann, H; Santi, L; Becks, K H; Lenzen, G; Linder, C

    2001-01-01

    Prototype sensors for the ATLAS silicon pixel detector have been electrically characterized. The current and voltage characteristics, charge collection efficiencies, and resolutions have been examined. Devices were fabricated on oxygenated and standard detector-grade silicon wafers. Results from prototypes which examine p-stop and standard and moderated p-spray isolation are presented for a variety of geometrical options. Some of the comparisons relate unirradiated sensors with those that have received fluences relevant to LHC operation.

  2. Investigations on the detection of irradiated food by measuring the viscosity of suspended spices and dried vegetables

    Science.gov (United States)

    Heide, L.; Nürnberger, E.; Bögl, K. W.

    Studies on the viscosity behavior were performed with 20 different spices or dried vegetables. In nine spices (cinnamon, ginger, mustard seed, celery, onions, shallots, lemon peel, black and white pepper) differences between unirradiated and irradiated samples were observed. Further lots were investigated to estimate the variations of viscosity depending on the origin of the samples. Additional storage experiments showed that measuring the viscosity may be a simple method to identify some radiation treated spices even after years.

  3. Application of irradiated chitosan for fruit preservation

    Energy Technology Data Exchange (ETDEWEB)

    Lan, K.N. [Post-harvest Technology Institute, 4, Ngo Quyen-Ha Noi (Viet Nam); Lam, N.D. [Ha Noi Radiation Center, VAEC, 5T-160, Nghiado, Tuliem, Ha Noi (Viet Nam); Kume, Tamikazu [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment

    2000-03-01

    Preliminary test of mango (Mangifera indica) preservation by irradiated chitosan coating has been investigated. The coating by using irradiated chitosan in 1.5% solution has extended the shelf life of mango from 7 to 15 days. At the 15th day mango coated by irradiated chitosan has been keeping good color, natural ripening, without spoilage, weight loss 10%, whereas the mango without coating was spoiled completely and the coating of fruit with unirradiated chitosan inhibited the ripening. (author)

  4. Bystander effect in human hepatoma HepG2 cells caused by medium transfers at different times after high-LET carbon ion irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Wu Qingfeng [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Key Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences, Lanzhou 730000 (China); Graduate School of Chinese Academy of Sciences, Beijing 100039 (China); Li Qiang, E-mail: liqiang@impcas.ac.c [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Key Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences, Lanzhou 730000 (China); Jin Xiaodong; Liu Xinguo [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Key Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences, Lanzhou 730000 (China); Dai Zhongying [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Key Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences, Lanzhou 730000 (China); Graduate School of Chinese Academy of Sciences, Beijing 100039 (China)

    2011-01-15

    Although radiation-induced bystander effects have been well documented in a variety of biological systems, whether irradiated cells have the ability to generate bystander signaling persistently is still unclear and the clinical relevance of bystander effects in radiotherapy remains to be elucidated. This study examines tumor cellular bystander response to autologous medium from cell culture irradiated with high-linear energy transfer (LET) heavy ions at a therapeutically relevant dose in terms of clonogenic cell survival. In vitro experiments were performed using human hepatoma HepG2 cell line exposed to 100 keV/{mu}m carbon ions at a dose of 2 Gy. Two different periods (2 and 12 h) after irradiation, irradiated cell conditioned medium (ICCM) and replenished fresh medium were harvested and then transferred to unirradiated bystander cells. Cellular bystander responses were measured with the different medium transfer protocols. Significant higher survival fractions of unirradiated cells receiving the media from the irradiated cultures at the different times post-irradiation than those of the control were observed. Even replenishing fresh medium for unirradiated cells which had been exposed to the ICCM for 12 h could not prevent the bystander cells from the increased survival fraction. These results suggest that the irradiated cells could release unidentified signal factor(s), which induced the increase in survival fraction for the unirradiated bystander cells, into the media sustainedly and the carbon ions triggered a cascade of signaling events in the irradiated cells rather than secreting the soluble signal factor(s) just at a short period after irradiation. Based on the observations in this study, the importance of bystander effect in clinical radiotherapy was discussed and incorporating the bystander effect into the current radiobiological models, which are applicable to heavy ion radiotherapy, is needed urgently.

  5. An automatic method to analyze the Capacity-Voltage and Current-Voltage curves of a sensor

    CERN Document Server

    Matorras Cuevas, Pablo

    2017-01-01

    An automatic method to perform Capacity versus voltage analysis for all kind of silicon sensor is provided. It successfully calculates the depletion voltage to unirradiated and irradiated sensors, and with measurements with outliers or reaching breakdown. It is built using C++ and using ROOT trees with an analogous skeleton as TRICS, where the data as well as the results of the ts are saved, to make further analysis.

  6. Diffusion in the system K2O-SrO-SiO2. II - Cation self-diffusion coefficients.

    Science.gov (United States)

    Varshneya, A. K.; Cooper, A. R.

    1972-01-01

    The self-diffusion coefficients were measured by introducing a slab of glass previously irradiated in a reactor between two slabs of unirradiated glass. By heating the specimens, etching them sequentially and determining the radioactivity, self-diffusion coefficients for K and Sr were measured. It is pointed out that the results obtained in the investigations appear to support the proposal that the network of the base glass predominantly controls the activation energy for the diffusion of ions.

  7. Fungal decontamination and enhancement of shelf life of edible split beans of wild legume Canavalia maritima by the electron beam irradiation

    Science.gov (United States)

    Supriya, P.; Sridhar, K. R.; Ganesh, S.

    2014-03-01

    Ripened split beans of the coastal sand dune wild legume Canavalia maritima serve as one of the traditional nutritional sources of the coastal dwellers in Southwest coast of India. Nine fungi were isolated from the unirradiated dry beans by plating on the potato dextrose agar medium. Toxigenic fungus Aspergillus niger showed the highest incidence (33-50%) followed by Aspergillus flavus (14-20%) and Penicillium chrysogenum (7-13%). Unirradiated dry beans and irradiated dry beans with electron beam doses 2.5, 5, 10 and 15 kGy were monitored for occurrence of fungal species and their incidence during 0, 3 and 6 months storage period under laboratory conditions. Irradiation resulted in dose-dependent decrease in fungal species (5-7, 4-6, 3-6 and 0 on irradiation at 0, 2.5, 5 and 10 or 15 kGy, respectively) as well as incidence (80-99, 19-46, 13-21 and 0%, respectively). Although aflatoxins (B1 and B2) were found below detectable level (<2 ng/g) in 0, 3 and 6 months stored unirradiated and irradiated beans (2.5 and 5 kGy), they were not present in beans irradiated with 10 and 15 kGy. In spite of occurrence of toxigenic fungus Aspergillus ochraceus in unirradiated and irradiated beans (2.5 and 5 kGy) stored for 3 and 6 months, the beans were devoid of ochratoxin-A. Electron beam irradiation dose 10 kGy could be recommended for fungal decontamination and improvement of shelf life of C. maritima ripened dry split beans.

  8. Advanced Characterization Techniques for SiC and PyC Coatings on High-Temperature Reactor Fuel Particles

    OpenAIRE

    Helary, D.; Dugne, O.; Bourrat, Xavier

    2008-01-01

    International audience; Enhancing the safety of high-temperature reactors (HTRs) is based on the quality of the fuel particles, requiring good knowledge of the microstructure of the four-layer particles designed to retain the fission products during irradiation and under accidental conditions. This paper focuses on the intensive research work performed to characterize the micro- and nanostructure of each unirradiated layer (silicon carbide and pyrocarbon coatings). The analytic expertise deve...

  9. Thermophysical and mechanical properties of Fe-(8-9)%Cr reduced activation steels

    Energy Technology Data Exchange (ETDEWEB)

    Zinkle, S.J.; Robertson, J.P.; Klueh, R.L. [Oak Ridge National Lab., TN (United States)

    1998-09-01

    The key thermophysical and mechanical properties for 8--9%Cr reduced activation ferritic/martensitic steels are summarized, including temperature-dependent tensile properties in the unirradiated and irradiated conditions, stress-rupture behavior, elastic constants, thermal conductivity, thermal expansion, specific heat, and ductile-to-brittle transition temperature. The estimated lower and upper temperatures limits for structural applications are 250 and 550 C due to radiation hardening/embrittlement and thermal creep considerations, respectively.

  10. Applicability of impedance measuring method to the detection of irradiation treatment of potatoes

    Energy Technology Data Exchange (ETDEWEB)

    Hayashi, Toru; Todoriki, Setsuko; Otobe, Kazunori; Sugiyama, Junnichi (National Food Research Inst., Tsukuba, Ibaraki (Japan))

    1993-05-01

    The incubation condition of potato tubers prior to impedance measurement greatly influenced the reliability of detection of irradiated potatoes; the impedance ratio at 5 kHz to 50 kHz (Z[sub 5k]/Z[sub 50k]) determined at 22degC at an apical region of tuber which was pre-incubated at 22degC for 3 days or longer resulted in the best detection of radiation treatment of potatoes. The impedance ratio was dependent upon dose applied to potato tubers. Potatoes irradiated at 100 Gy could be distinguished from unirradiated potatoes for 10 cultivars of potatoes. The impedance ratio of potatoes irradiated at the same dose was little influenced by the planting locality if the cultivar was the same, although the ratio varied with potato cultivars. These results indicate that irradiated potatoes can be detected if the potato cultivar is known. Potatoes 'Danshaku' commercially irradiated at the Shihiro Potato Irradiation Center could be differentiated from unirradiated 'Danshaku' at different planting localities; the impedance ratio was lower than 2.75 for the unirradiated potatoes and higher than 2.75 for the irradiated ones. (author).

  11. Identification of irradiated spices by the use of thermoluminescence method (TL)

    Energy Technology Data Exchange (ETDEWEB)

    Sharifzadeh, M.; Sohrabpour, M. (Atomic Energy Organization of Iran, Teheran (Iran, Islamic Republic of))

    In this paper the results of the investigation of identification of irradiated spices by the use of thermoluminescence method is reported. The materials used were black and red peppers, turmeric, cinnamon, and garlic powder. Gamma Cell 220 was used for irradiating samples at dose values of 2.5, 5, 7.5 and 10 kGy respectively. The TL intensity of the unirradiated spices as well as the fading characteristics of the irradiated samples having received a dose of 10 kGy have been measured. Post-irradiation temperature treatment of the irradiated (10 kGy) and unirradiated samples at 60[sup o]C and 100[sup o]C for 24 hours have also been performed. The results show that the TL intensities of unirradiated and irradiated samples from different batches of each spice are fairly distributed. A reasonable TL intensity versus dose has been observed in nearly all cases. Based on the observation made it is possible to distinguish irradiated spices after (4-9) months post-irradiation. (author).

  12. Physicochemical evaluation of the effects of irradiation and evisceration on the conservation of refrigerated blackfin tuna (Thunnus atlanticus)

    Energy Technology Data Exchange (ETDEWEB)

    Monteiro, Maria L.G.; Marsico, Eliane T. [Universidade Federal Fluminense (UFF), Niteroi, RJ (Brazil). Faculdade de Veterinaria. Dept. de Tecnologia de Alimentos], e-mail: marialuciaguerra@yahoo.com.br, e-mail: elianee@vm.uff.br; Vital, Helio C. [Centro Tecnologico do Exercito (CTEx), Rio de Janeiro, RJ (Brazil). Secao de Defesa Nuclear], e-mail: vital@ctex.eb.br

    2009-07-01

    Tuna is among the most traded fishes in Brazil, however efficiently delaying its fast deterioration is still a major practical challenge. Irradiation has been proposed as a safe and powerful alternative tool for conservation of seafood. This work investigated the effects of irradiation on the physicochemical quality of refrigerated blackfin tuna (Thunnus atlanticus). Analyses of pH, total volatile bases (TVB-N), ammonia and biogenic amines (histamine, cadaverine and putrescine) were performed in order to determine the degree of conservation. The samples were subjected to four different treatments aiming at evaluating the efficiency of irradiation, evisceration and both combined. The figures measured for those parameters, all of them related to the degree of conservation, were found to increase with time regardless of the treatment. In addition, data for irradiated samples remained consistently lower than for unirradiated ones, indicating a better level of preservation that led to an extended shelf life of 14 days. In contrast, excessive levels of those indicators of degradation were found in unirradiated samples after 7 to 10 days of storage. In addition, some evidence was found that evisceration slightly increased quality, consequently promoting a small extension in shelf life of unirradiated samples. Finally, it can be concluded with basis on the results of the physicochemical parameters studied that treatment of fresh refrigerated blackfin tuna by irradiation with 2.5 kGy efficiently preserved freshness and extended the shelf life of the product from 7 to 14 days. (author)

  13. Modification of radiation carcinogenesis by marihuana

    Energy Technology Data Exchange (ETDEWEB)

    Montour, J.L.; Dutz, W.; Harris, L.S.

    1981-03-15

    Male, female, and ovariectomized female Sprague-Dawley rats were irradiated with 400 rads, 150 rads, or 300 rads, respectively, of /sup 60/Co gamma rays when they were between 40 and 50 days of age. The animals were injected three times weekly with either marihuana extract or with alcohol-emulphor carrier. Comparable unirradiated groups were similarly injected. Mean survival time in males was significantly shorter in the 400 rad + marihuana group compared with the three other groups whose mean survival times did not differ. Through the 546 days that the males were observed, the total number of tumors other than fibrosarcomas was significantly greater following radiation and marihuana (22) than radiation alone (6). Fifteen of the tumors were of breast or endocrine tissues. No differences were seen in the unirradiated groups. In the females, which were observed for 635 days, the total number of breast tumors was greater with the combined treatment (38) compared with radiation alone (22). This was entirely due to a marked difference in the adenocarcinoma incidence, which was 21 (radiation + marihuana) compared with four (radiation alone). The number of adenofibromas was similar in the two groups. In the unirradiated female groups the breast adenocarcinoma incidence was eight in the marihuana group and two in the control group. Ovariectomy resulted in a lower breast tumor incidence in all groups. Nonbreast tumors were more frequent in the ovariectomized-irradiated groups. Radiation plus marihuana produced more nonbreast tumors (25) than radiation alone (17) in the ovariectomized females.

  14. Modification of radiation carcinogenesis by marijuana

    Energy Technology Data Exchange (ETDEWEB)

    Montour, J.L.; Dutz, W.; Harris, L.S.

    1981-03-15

    Male, female, and ovariectomized female Sprague-Dawley rats were irradiated with 400 rads, 150 rads, or 300 rads, respectively, of /sup 60/Co gamma rays when they were between 40 and 50 days of age. The animals were injected three times weekly with either marihuana extract or with alcohol-emulphor carrier. Comparable unirradiated groups were similarly injected. Mean survival time in males was significantly shorter in the 400 rad + marihuana group compared with the three other groups whose mean survival times did not differ. Through the 546 days that the males were observed, the total number of tumors other than fibrosarcomas was significantly greater following radiation and marihuana (22) than radiation alone (6). Fifteen of the tumors were of breast or endocrine tissues. No differences were seen in the unirradiated groups. In the females, which were observed for 635 days, the total number of breast tumors was greater with the combined treatment (38) compared with radiation alone (22). This was entirely due to a marked difference in the adenocarcinoma incidence, which was 21 (radiation + marihuana) compared with four (radiation alone). The number of adenofibromas was similar in the two groups. In the unirradiated female groups the breast adenocarcinoma incidence was eight in the marihuana group and two in the control group. Ovariectomy resulted in a lower breast tumor incidence in all groups. Nonbreast tumors were more frequent in the ovariectomized-irradiated groups. Radiation plus marihuana produced more nonbreast tumors (25) than radiation alone (17) in the ovariectomized females.

  15. Fracture toughness and fatigue crack growth of oxide dispersion strengthened copper

    Energy Technology Data Exchange (ETDEWEB)

    Alexander, D.J.; Gieseke, B.G. [Oak Ridge National Laboratory, TN (United States)

    1996-04-01

    The fracture toughness and fatigue crack growth behavior of copper dispersion strengthened with aluminum oxide (0.15 wt % Al) was examined. In the unirradiated condition, the fracture toughness was about 45 kJ/m{sup 2} (73 MPa{radical}m) at room temperature, but decreased significantly to only 3 Kj/m{sup 2} (20 MPa{radical}m), at 250{degrees}C. After irradiation at approximately 250{degrees}C to about 2.5 displacements per atom (dpa), the toughness was very low, about 1 kJ/m{sup 2} (48 MOa{radical}m), and at 250{degrees}C the toughness was very low, about 1kJ/m{sup 2} (12 mPa{radical}m). The fatigue crack growth rate of unirradiated material at room temperature is similiar to other candidate structural alloys such as V-4Cr-4Ti and 316L stainless steel. The fracture properties of this material at higher temperatures and in controlled environments need further investigation, in both irradiated and unirradiated conditions.

  16. Reprocessing technology development for irradiated beryllium

    Energy Technology Data Exchange (ETDEWEB)

    Kawamura, H.; Sakamoto, N. [Oarai Research Establishment, Ibaraki-ken (Japan); Tatenuma, K. [KAKEN Co., Ibaraki-ken (Japan)] [and others

    1995-09-01

    At present, beryllium is under consideration as a main candidate material for neutron multiplier and plasma facing material in a fusion reactor. Therefore, it is necessary to develop the beryllium reprocessing technology for effective resource use. And, we have proposed reprocessing technology development on irradiated beryllium used in a fusion reactor. The preliminary reprocessing tests were performed using un-irradiated and irradiated beryllium. At first, we performed beryllium separation tests using un-irradiated beryllium specimens. Un-irradiated beryllium with beryllium oxide which is a main impurity and some other impurities were heat-treated under chlorine gas flow diluted with Ar gas. As the results high purity beryllium chloride was obtained in high yield. And it appeared that beryllium oxide and some other impurities were removed as the unreactive matter, and the other chloride impurities were separated by the difference of sublimation temperature on beryllium chloride. Next, we performed some kinds of beryllium purification tests from beryllium chloride. And, metallic beryllium could be recovered from beryllium chloride by the reduction with dry process. In addition, as the results of separation and purification tests using irradiated beryllium specimens, it appeared that separation efficiency of Co-60 from beryllium was above 96%. It is considered that about 4% Co-60 was carried from irradiated beryllium specimen in the form of cobalt chloride. And removal efficiency of tritium from irradiated beryllium was above 95%.

  17. Investigation of gamma radiation induced changes in local structure of borosilicate glass by TDPAC and EXAFS

    Energy Technology Data Exchange (ETDEWEB)

    Kumar, Ashwani, E-mail: kashwani@barc.gov.in [Bhabha Atomic Research Centre, Radioanalytical Chemistry Division (India); Nayak, C.; Rajput, P. [Bhabha Atomic Research Centre, Atomic and Molecular Physics Division (India); Mishra, R. K. [Bhabha Atomic Research Centre, Waste Management Division (India); Bhattacharyya, D. [Bhabha Atomic Research Centre, Atomic and Molecular Physics Division (India); Kaushik, C. P. [Bhabha Atomic Research Centre, Waste Management Division (India); Tomar, B. S. [Bhabha Atomic Research Centre, Radioanalytical Chemistry Division (India)

    2016-12-15

    Gamma radiation induced changes in local structure around the probe atom (Hafnium) were investigated in sodium barium borosilicate (NBS) glass, used for immobilization of high level liquid waste generated from the reprocessing plant at Trombay, Mumbai. The (NBS) glass was doped with {sup 181}Hf as a probe for time differential perturbed angular correlation (TDPAC) spectroscopy studies, while for studies using extended X-ray absorption fine structure (EXAFS) spectroscopy, the same was doped with 0.5 and 2 % (mole %) hafnium oxide. The irradiated as well as un-irradiated glass samples were studied by TDPAC and EXAFS techniques to obtain information about the changes (if any) around the probe atom due to gamma irradiation. TDPAC spectra of unirradiated and irradiated glasses were similar and reminescent of amorphous materials, indicating negligible effect of gamma radiation on the microstructure around Hafnium probe atom, though the quaqdrupole interaction frequency (ω{sub Q}) and asymmetry parameter (η) did show a marginal decrease in the irradiated glass compared to that in the unirradiated glass. EXAFS measurements showed a slight decrease in the Hf-O bond distance upon gamma irradiation of Hf doped NBS glass indicating densification of the glass matrix, while the cordination number around hafnium remains unchanged.

  18. Effects of heavy-ion radiosurgery on the hemopoietic function of the silkworm Bombyx mori

    Energy Technology Data Exchange (ETDEWEB)

    Tu, Zhen-Li; Kobayashi, Yasuhiko; Watanabe, Hiroshi; Yamamoto, Kazuo [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment; Kiguchi, Kenji [SHINSHU Univ., Ueda, Nagano (Japan). Faculty of Textile Science and Technology

    2002-09-01

    To study the effects of heavy-ion radiosurgery on the hemopoietic function of a silkworm, hemopoietic organs of larvae were locally irradiated with carbon-ion beams, and the changes in the hemocyte density and in the hemocyte function were investigated. When the larvae were irradiated by 50 Gy to 300 Gy carbon ions on the 3rd day of the 4th instar, the hemocyte densities did not change for a while, though they gradually increased at a later stage, but were finally still significantly lower than those of unirradiated controls. The hemocyte densities of the larvae irradiated at different developmental stages showed suppressed increments, and carbon-ion irradiation given to larvae at early stages compared to the later stages had a significant suppressive effect on the hemocyte densities. On unilateral irradiated larvae a hemocyte intermediate increment between those of bilateral irradiated larvae and unirradiated controls was observed. The percentage of dead hemocytes was obviously higher for irradiated larvae than unirradiated controls during the later 5th instar. Thus, it is evident that carbon-ion radiosurgery on hemopoietic organs of silkworm induced not only a quantitative change, but also a qualitative change in the hemocytes. (author)

  19. The effect of fuel chemistry on UO2 dissolution

    Energy Technology Data Exchange (ETDEWEB)

    Casella, Amanda; Hanson, Brady; Miller, William

    2016-08-01

    The dissolution rate of both unirradiated UO2 and used nuclear fuel has been studied by numerous countries as part of the performance assessment of proposed geologic repositories. In the scenario of waste package failure and groundwater infiltration into the fuel, the effects of variables such as temperature, dissolved oxygen, and water and fuel chemistry on the dissolution rates of the fuel are necessary to provide a quantitative estimate of the potential release over geologic time frames. The primary objective of this research was to determine the influence these parameters have on the dissolution rate of unirradiated UO2 under repository conditions and compare them to the rates predicted by current dissolution models. Both unirradiated UO2 and UO2 doped with varying concentrations of Gd2O3, to simulate used fuel composition after long time periods where radiolysis has minor contributions to dissolution, were examined. In general, a rise in temperature increased the dissolution rate of UO2 and had a larger effect on pure UO2 than on those doped with Gd2O3. Oxygen dependence was observed in the UO2 samples with no dopant and increased as the temperature rose; in the doped fuels less dependence was observed. The addition of gadolinia into the UO2 matrix showed a significant decrease in the dissolution rate. The matrix stabilization effect resulting from the dopant proved even more beneficial in lowering the dissolution rate at higher temperatures and dissolved O2 concentrations in the leachate where the rates would typically be elevated.

  20. EPR investigation of some traditional oriental irradiated spices

    Science.gov (United States)

    Duliu, Octavian G.; Georgescu, Rodica; Ali, Shaban Ibrahim

    2007-06-01

    The 9.50 GHz electron paramagnetic resonance (EPR) spectra of unirradiated and 60Co γ-ray irradiated cardamom ( Elettaria cardamomum L. Maton, Zingiberaceae), ginger (( Zingiber officinale Rosc., Zingiberaceae), and saffron ( Crocus sativus L., Iridaceae) have been investigated at room temperature. All unirradiated spices presented a weak resonance line with g-factors around free-electron ones. After γ-ray irradiation at an absorbed dose of up to 11.3 kGy, the presence of EPR spectra whose amplitude increase monotonously with the absorbed dose has been noticed with all spices. A 100 °C isothermal annealing of 11.3 kGy irradiated samples has shown a differential reduction of amplitude of various components that compose initial spectra, but even after 3.6 h of thermal treatment, the remaining amplitude represents no less then 30% of the initial ones. The same peculiarities have been noticed after 83 days storage at room temperature but after 340 days storage at ambient conditions only irradiated ginger displays a weak signal that differs from those of unirradiated sample. All these factors could be taken into account in establishing at which extent the EPR is suitable to evidence any irradiation treatment applied to these spices.

  1. Depth profile study on Raman spectra of high-energy-electron-irradiated hydrogenated amorphous silicon films

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    According to the different penetration depths for the incident lights of 472 nm and 532 nm in hydrogenated amorphous silicon (a-Si:H) thin films, the depth profile study on Raman spectra of a-Si:H films was carried out. The network ordering evolution in the near surface and interior region of the unirradiated and irradiated a-Si:H films was investigated. The results show that there is a structural improvement in the shortand intermediate-range order towards the surface of the unirradiated a-Si:H films. The amorphous silicon network in the near and interior region becomes more disordered on the shortand intermediate-range scales after being irradiated with high energy electrons. However, the surface of the irradiated films becomes more disordered in comparison with their interior region, indicating that the created defects caused by electron irradiation are concentrated in the near surface of the irradiated films. Annealing eliminates the irradiation effects on a-Si:H thin films and the structural order of the irradiated films is similar to that of the unirradiated ones after being annealed. There exists a structural improvement in the shortand intermediate-range order towards the surface of the irradiated a-Si:H films after being annealed.

  2. Hybrid Gama Emission Tomography (HGET): FY16 Annual Report

    Energy Technology Data Exchange (ETDEWEB)

    Miller, Erin A.; Smith, Leon E.; Wittman, Richard S.; Campbell, Luke W.; Deshmukh, Nikhil S.; Zalavadia, Mital A.; Batie, Margo A.; Mozin, Vladimir V.

    2017-02-01

    Current International Atomic Energy Agency (IAEA) methodologies for the verification of fresh low-enriched uranium (LEU) and mixed oxide (MOX) fuel assemblies are volume-averaging methods that lack sensitivity to individual pins. Further, as fresh fuel assemblies become more and more complex (e.g., heavy gadolinium loading, high degrees of axial and radial variation in fissile concentration), the accuracy of current IAEA instruments degrades and measurement time increases. Particularly in light of the fact that no special tooling is required to remove individual pins from modern fuel assemblies, the IAEA needs new capabilities for the verification of unirradiated (i.e., fresh LEU and MOX) assemblies to ensure that fissile material has not been diverted. Passive gamma emission tomography has demonstrated potential to provide pin-level verification of spent fuel, but gamma-ray emission rates from unirradiated fuel emissions are significantly lower, precluding purely passive tomography methods. The work presented here introduces the concept of Hybrid Gamma Emission Tomography (HGET) for verification of unirradiated fuels, in which a neutron source is used to actively interrogate the fuel assembly and the resulting gamma-ray emissions are imaged using tomographic methods to provide pin-level verification of fissile material concentration.

  3. EPR investigation of some traditional oriental irradiated spices

    Energy Technology Data Exchange (ETDEWEB)

    Duliu, Octavian G. [University of Bucharest, Department of Atomic and Nuclear Physics, Magurele, C.P. MG-11, RO-077125 Bucharest (Romania)]. E-mail: duliu@pcnet.ro; Georgescu, Rodica [National Institute for Physics and Nuclear Engineering -Horia Hulubei, C.P. MG-6, RO-077125 Bucharest (Romania); Ali, Shaban Ibrahim [University of Bucharest, Department of Atomic and Nuclear Physics, Magurele, C.P. MG-11, RO-077125 Bucharest (Romania)

    2007-06-15

    The 9.50 GHz electron paramagnetic resonance (EPR) spectra of unirradiated and {sup 60}Co {gamma}-ray irradiated cardamom (Elettaria cardamomum L. Maton, Zingiberaceae), ginger ((Zingiber officinale Rosc., Zingiberaceae), and saffron (Crocus sativus L., Iridaceae) have been investigated at room temperature. All unirradiated spices presented a weak resonance line with g-factors around free-electron ones. After {gamma}-ray irradiation at an absorbed dose of up to 11.3 kGy, the presence of EPR spectra whose amplitude increase monotonously with the absorbed dose has been noticed with all spices. A 100 {sup o}C isothermal annealing of 11.3 kGy irradiated samples has shown a differential reduction of amplitude of various components that compose initial spectra, but even after 3.6 h of thermal treatment, the remaining amplitude represents no less then 30% of the initial ones. The same peculiarities have been noticed after 83 days storage at room temperature but after 340 days storage at ambient conditions only irradiated ginger displays a weak signal that differs from those of unirradiated sample. All these factors could be taken into account in establishing at which extent the EPR is suitable to evidence any irradiation treatment applied to these spices.

  4. Influence of helium-neon laser irradiation on seed germination in vitro and physico-biochemical characters in seedlings of brinjal (Solanum melongena L.) var. Mattu Gulla.

    Science.gov (United States)

    Muthusamy, Annamalai; Kudwa, Prathibha P; Prabhu, Vijendra; Mahato, Krishna K; Babu, Vidhu Sankar; Rao, Mattu Radhakrishna; Gopinath, Puthiya Mandyat; Satyamoorthy, Kapaettu

    2012-01-01

    In the present study, the seeds of brinjal (Solanum melongena L.) var. Mattu Gulla were irradiated with single exposure of He-Ne laser at different doses of 5-40 J cm(-2) and germinated aseptically. Thirty day old seedlings were harvested and the germination, growth, physiological and biochemical parameters were estimated and compared with un-irradiated control seedlings. A significant enhancement in growth characters were noted with respect to length, fresh and dry weight of shoots and roots. In addition, chlorophyll (a and b), carotenoid content, anthocyanin and amylases (α and β) activities were found to be altered. Significant alterations in percentage of seed germination (P < 0.001) and time to 50% germination (P < 0.001) were observed in the irradiated seeds compared with the un-irradiated controls. In conclusion, the results of the present study demonstrated that low dose (5-30 J cm(-2) ) of He-Ne laser irradiation enhanced the germination process and altered growth, by positively influencing physiological and biochemical parameters of the brinjal seedlings compared with un-irradiated control under in vitro conditions.

  5. Hydrogen uptake in Zircaloy-2 reactor fuel claddings studied with elastic recoil detection

    Science.gov (United States)

    Rajasekhara, S.; Doyle, B. L.; Enos, D. G.; Clark, B. G.

    2013-04-01

    The recent trend towards a high burn-up discharge spent nuclear fuel necessitates a thorough understanding of hydrogen uptake in Zr-based cladding materials that encapsulate spent nuclear fuel. Although it is challenging to experimentally replicate exact conditions in a nuclear reactor that lead to hydrogen uptake in claddings, in this study we have attempted to understand the kinetics of hydrogen uptake by first electrolytically charging Zircaloy-2 (Zr-2) cladding material for various durations (100 to 2,600 s), and subsequently examining hydrogen ingress with elastic recoil detection (ERD) and transmission electron microscopy (TEM). To understand the influence of irradiation damage defects on hydrogen uptake, an analogous study was performed on ion - irradiated (0.1, 1 and 25 dpa) Zr-2. Analysis of ERD data from the un-irradiated Zr-2 suggests that the growth of the hydride layer is diffusion controlled, and preliminary TEM results support this assertion. In un-irradiated Zr-2, the diffusivity of hydrogen in the hydride phase was found to be approximately 1.1 × 10-11 cm2/s, while the diffusivity in the hydride phase for lightly irradiated (0.1 and 1 dpa) Zr-2 is an order of magnitude lower. Irradiation to 25 dpa results in a hydrogen diffusivity that is comparable to the un-irradiated Zr-2. These results are compared with existing literature on hydrogen transport in Zr - based materials.

  6. Studies on immunity to Schistosoma mansoni in vivo: whole-body irradiation has no effect on vaccine-induced resistance in mice

    Energy Technology Data Exchange (ETDEWEB)

    Vignali, D.A.A.; Bickle, Q.D.; Taylor, M.G.

    1988-02-01

    Actively immunized mice, whole-body irradiated with 650 or 525 rad., manifested comparable levels of resistance to Schistosoma mansoni compared with unirradiated, immunized mice in spite of a marked reduction in circulating leucocytes and platelets, and despite an abrogation of delayed-type hypersensitivity (DTH) (Type IV) reponse to schistosomular antigens. However, limited histopathological comparison of lung sections from irradiated and unirradiated mice 7 days post-challenge showed that cellular reactions ('foci') around parasites were similar in size and cellular composition except that in irradiated mice, eosinophils were poorly represented both in the foci and in lung tissue in general. Neither presumed immune complex-mediated (Type III, Arthus reaction) hypersensitivity nor serum anti-schistosomulum extract antibody levels were affected. The pattern of /sup 125/I-labelled schistosomular surface antigens immunoprecipitated with serum from irradiated and unirradiated mice was essentially similar. These results are consistent with antibody playing an important role in vaccine-induced immunity in mice but suggest that radiosensitive T cell function and radiosensitive cells, such as platelets and polymorphonuclear cells, including eosinophils, may not be essential.

  7. Investigation of gamma radiation induced changes in local structure of borosilicate glass by TDPAC and EXAFS

    Science.gov (United States)

    Kumar, Ashwani; Nayak, C.; Rajput, P.; Mishra, R. K.; Bhattacharyya, D.; Kaushik, C. P.; Tomar, B. S.

    2016-12-01

    Gamma radiation induced changes in local structure around the probe atom (Hafnium) were investigated in sodium barium borosilicate (NBS) glass, used for immobilization of high level liquid waste generated from the reprocessing plant at Trombay, Mumbai. The (NBS) glass was doped with 181Hf as a probe for time differential perturbed angular correlation (TDPAC) spectroscopy studies, while for studies using extended X-ray absorption fine structure (EXAFS) spectroscopy, the same was doped with 0.5 and 2 % (mole %) hafnium oxide. The irradiated as well as un-irradiated glass samples were studied by TDPAC and EXAFS techniques to obtain information about the changes (if any) around the probe atom due to gamma irradiation. TDPAC spectra of unirradiated and irradiated glasses were similar and reminescent of amorphous materials, indicating negligible effect of gamma radiation on the microstructure around Hafnium probe atom, though the quaqdrupole interaction frequency ( ω Q) and asymmetry parameter ( η) did show a marginal decrease in the irradiated glass compared to that in the unirradiated glass. EXAFS measurements showed a slight decrease in the Hf-O bond distance upon gamma irradiation of Hf doped NBS glass indicating densification of the glass matrix, while the cordination number around hafnium remains unchanged.

  8. Uptake and transport of positron-emitting tracer in plants

    Energy Technology Data Exchange (ETDEWEB)

    Kume, Tamikazu; Matsuhashi, Shinpei; Shimazu, Masamitsu [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment] [and others

    1997-03-01

    The transport of a positron-emitting isotope introduced into a plant was dynamically followed by a special observation apparatus called `Positron-Emitting Tracer Imaging System`. In the system, annihilation {gamma}-rays from the positron emitter are detected with two planer detectors (5 x 6 cm square). The water containing ca. 5 MBq/ml of {sup 18}F was fed to the cut stem of soybean for 2 min and then the images of tracer activity were recorded for 30 - 50 min. When the midrib of a leaf near the petiole was cut just before measurement, the activity in the injured leaf was decreased but detected even at the apex. This result suggests that the damaged leaf recovered the uptake of water through the lamina. Maximum tracer activities in leaves of unirradiated plant were observed within 10 min, whereas those of irradiated plant at 100 Gy were observed after over 25 min. The final activity of irradiated plant after 30 min was lower than that of unirradiated plant. In case of beans, there was a difference in the absorption behavior of the {sup 18}F-labeled water between unirradiated and irradiated samples. These results show that the system is effective to observe the uptake and transportation of water containing positron emitting tracer for the study of damage and recovery functions of plants. (author)

  9. Reconstituted Charpy impact specimens. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Perrin, J.S.; Wullaert, R.A.; McConnell, P.; Server, W.L.; Fromm, E.O.

    1982-12-01

    The arc stud welding process was used to produce new, full size Charpy V-notch impact specimens from halves of Charpy specimens which had been previously tested. The apparatus was developed such that it could be used not only for unirradiated specimens, but also so that it could be adapted for in-cell use to produce new reconstituted specimens of irradiated material. The materials studied are of interest in nuclear applications. They include A533B, A36, A516-80, submerged arc weld metal (A508 base metal), HY80, cast duplex stainless steel, irradiated A533B, and irradiated submerged arc weld metal (A508 base metal). Both unirradiated and irradiated specimens were successfully produced and subsequently impact tested. In general, there was excellent agreement when comparing the original curves to the subsequent curves generated with reconstituted specimens. This program has shown that the arc stud welding process is well suited for producing reconstituted specimens at a reasonable cost using either unirradiated or irradiated material.

  10. Modeling and Testing Miniature Torsion Specimens for SiC Joining Development Studies for Fusion

    Energy Technology Data Exchange (ETDEWEB)

    Henager, Charles H.; Nguyen, Ba Nghiep; Kurtz, Richard J.; Roosendaal, Timothy J.; Borlaug, Brennan A.; Ferraris, Monica; Ventrella, Andrea; Katoh, Yutai

    2015-08-19

    The international fusion community has designed a miniature torsion specimen for neutron irradiation studies of joined SiC and SiC/SiC composite materials. Miniature torsion joints based on this specimen design were fabricated using displacement reactions between Si and TiC to produce Ti3SiC2 + SiC joints with CVD-SiC and tested in torsion-shear prior to and after neutron irradiation. However, many of these miniature torsion specimens fail out-of-plane within the CVD-SiC specimen body, which makes it problematic to assign a shear strength value to the joints and makes it difficult to compare unirradiated and irradiated joint strengths to determine the effects of the irradiation. Finite element elastic damage and elastic-plastic damage models of miniature torsion joints are developed that indicate shear fracture is likely to occur within the body of the joined sample and cause out-of-plane failures for miniature torsion specimens when a certain modulus and strength ratio between the joint material and the joined material exists. The model results are compared and discussed with regard to unirradiated and irradiated joint test data for a variety of joint materials. The unirradiated data includes Ti3SiC2 + SiC/CVD-SiC joints with tailored joint moduli, and includes steel/epoxy and CVD-SiC/epoxy joints. The implications for joint data based on this sample design are discussed.

  11. Apparatus for rendering at least a portion of a device inoperable and related methods

    Science.gov (United States)

    Daniels, Michael A.; Steffler, Eric D.; Hartenstein, Steven D.; Wallace, Ronald S.

    2016-11-08

    Apparatus for rendering at least a portion of a device inoperable may include a containment structure having a first compartment that is configured to receive a device therein and a movable member configured to receive a cartridge having reactant material therein. The movable member is configured to be inserted into the first compartment of the containment structure and to ignite the reactant material within the cartridge. Methods of rendering at least a portion of a device inoperable may include disposing the device into the first compartment of the containment structure, inserting the movable member into the first compartment of the containment structure, igniting the reactant material in the cartridge, and expelling molten metal onto the device.

  12. Electronic Vapor Cigarette Battery Explosion Causing Shotgun-like Superficial Wounds and Contusion

    Directory of Open Access Journals (Sweden)

    Siri Shastry, MD

    2016-03-01

    Full Text Available INTRODUCTION Electronic vapor cigarettes (E-cigarettes were created in 2003 as an alternative to traditional tobacco cigarettes. E-cigarettes have been available in the United States since 2006.1 The typical E-cigarette consists of a cartridge that contains liquid, an atomizer that heats the liquid (i.e. acts as a vaporizer, as well as a battery. The liquid contained within the cartridge contains nicotine, propylene glycol and/ or glycerol as well as flavorings. The consumer uses an E-cigarette through either pushing a button or inhalation, which triggers heating and therefore aerosolizes the liquid within the cartridge, emulating cigarette “smoke.” The newest E-cigarettes are larger than nicotine cigarettes and employ stronger, rechargeable batteries as a power source.2,3

  13. Photocathode device that replenishes photoemissive coating

    Energy Technology Data Exchange (ETDEWEB)

    Moody, Nathan A.; Lizon, David C.

    2016-06-14

    A photocathode device may replenish its photoemissive coating to replace coating material that desorbs/evaporates during photoemission. A linear actuator system may regulate the release of a replenishment material vapor, such as an alkali metal, from a chamber inside the photocathode device to a porous cathode substrate. The replenishment material deposits on the inner surface of a porous membrane and effuses through the membrane to the outer surface, where it replenishes the photoemissive coating. The rate of replenishment of the photoemissive coating may be adjusted using the linear actuator system to regulate performance of the photocathode device during photoemission. Alternatively, the linear actuator system may adjust a plasma discharge gap between a cartridge containing replenishment material and a metal grid. A potential is applied between the cartridge and the grid, resulting in ejection of metal ions from the cartridge that similarly replenish the photoemissive coating.

  14. Comparing Terminal Performance of .357 SIG and 9mm Bullets in Ballistic Gelatin Using Retarding Force Analysis from High Speed Video

    CERN Document Server

    Keys, Elizabeth; Courtney, Michael

    2015-01-01

    High-speed video has emerged as an valuable tool for quantifying bullet performance in ballistic gelatin. This paper presents the results of testing four .357 SIG bullets using high-speed video of bullet impacts in ballistic gelatin to determine retarding force curves, permanent cavities, temporary cavities, and energy deposit vs. penetration depth. Since the methods are identical, results are meaningfully compared with four 9mm NATO bullets studied in an earlier project. Though .357 SIG bullets perform slightly better due to higher impact energy, the principal finding is that there is a much bigger difference in performance between the best and worst performing bullets in each cartridge than there is between bullets of similar design in the two cartridges. In each cartridge, higher performing expanding bullets (jacketed hollow points) outperform non-expanding bullets (full metal jacket) by a wide margin, showing a much higher probability of rapid incapacitation according to an Army Research Laboratory model ...

  15. Autonomous detection of ISO fade point with color laser printers

    Science.gov (United States)

    Yan, Ni; Maggard, Eric; Fothergill, Roberta; Jessome, Renee J.; Allebach, Jan P.

    2015-01-01

    Image quality assessment is a very important field in image processing. Human observation is slow and subjective, it also requires strict environment setup for the psychological test 1. Thus developing algorithms to match desired human experiments is always in need. Many studies have focused on detecting the fading phenomenon after the materials are printed, that is to monitor the persistence of the color ink 2-4. However, fading is also a common artifact produced by printing systems when the cartridges run low. We want to develop an automatic system to monitor cartridge life and report fading defects when they appear. In this paper, we first describe a psychological experiment that studies the human perspective on printed fading pages. Then we propose an algorithm based on Color Space Projection and K-means clustering to predict the visibility of fading defects. At last, we integrate the psychological experiment result with our algorithm to give a machine learning tool that monitors cartridge life.

  16. Remotely serviced filter and housing

    Science.gov (United States)

    Ross, M.J.; Zaladonis, L.A.

    1987-07-22

    A filter system for a hot cell comprises a housing adapted for input of air or other gas to be filtered, flow of the air through a filter element, and exit of filtered air. The housing is tapered at the top to make it easy to insert a filter cartridge holds the filter element while the air or other gas is passed through the filter element. Captive bolts in trunnion nuts are readily operated by electromechanical manipulators operating power wrenches to secure and release the filter cartridge. The filter cartridge is adapted to make it easy to change a filter element by using a master-slave manipulator at a shielded window station. 6 figs.

  17. Apparatus for rendering at least a portion of a device inoperable and related methods

    Energy Technology Data Exchange (ETDEWEB)

    Daniels, Michael A.; Steffler, Eric D.; Hartenstein, Steven D.; Wallace, Ronald S.

    2016-11-08

    Apparatus for rendering at least a portion of a device inoperable may include a containment structure having a first compartment that is configured to receive a device therein and a movable member configured to receive a cartridge having reactant material therein. The movable member is configured to be inserted into the first compartment of the containment structure and to ignite the reactant material within the cartridge. Methods of rendering at least a portion of a device inoperable may include disposing the device into the first compartment of the containment structure, inserting the movable member into the first compartment of the containment structure, igniting the reactant material in the cartridge, and expelling molten metal onto the device.

  18. Engineering evaluation of solids/liquids separation processes applicable to sludge treatment project

    Energy Technology Data Exchange (ETDEWEB)

    Duncan, J.B.

    1998-08-25

    This engineering study looks at the solids/liquids separation unit operations after the acid dissolution of the K Basin sludge treatment. Unit operations considered were centrifugation, filtration (cartridge, cross flow, and high shear filtration) and gravity settling. The recommended unit operations for the solids/liquids separations are based upon the efficiency, complexity, and off-the-shelf availability and adaptability. The unit operations recommended were a Robatel DPC 900 centrifuge followed by a nuclearized 31WM cartridge filter. The Robatel DPC 900 has been successfully employed in the nuclear industry on a world wide scale. The 31WM cartridge filter has been employed for filtration campaigns in both the government and civilian nuclear arenas.

  19. EOUG2000: Web publishing using PL/SQL and JAVA

    CERN Document Server

    Grancher, Eric

    2000-01-01

    At CERN, as increasingly elsewhere, server based applications using the PL/SQL cartridge and Java are preferred as they make minimum demands on the client and ease maintenance. The PL/SQL cartridge, the original method offered by Oracle, has proved reliable and effective. We have used it to build web applications for more than four years. Newer applications are using Servlets together with the application server. This paper presents the different techniques that we designed and the pitfalls that we encountered in diverse projects such as a technology transfer database, a product management tool and a system to keep track of physics events. Important considerations are security, ease of maintenance, transaction handling and modularity. Most of the experience has been gained using the PL/SQL cartridge and this will be contrasted and compared with the newer Java techniques…

  20. Development of ballistics identification—from image comparison to topography measurement in surface metrology

    Science.gov (United States)

    Song, J.; Chu, W.; Vorburger, T. V.; Thompson, R.; Renegar, T. B.; Zheng, A.; Yen, J.; Silver, R.; Ols, M.

    2012-05-01

    Fired bullets and ejected cartridge cases have unique ballistics signatures left by the firearm. By analyzing the ballistics signatures, forensic examiners can trace these bullets and cartridge cases to the firearm used in a crime scene. Current automated ballistics identification systems are primarily based on image comparisons using optical microscopy. The correlation accuracy depends on image quality which is largely affected by lighting conditions. Because ballistics signatures are geometrical micro-topographies by nature, direct measurement and correlation of the surface topography is being investigated for ballistics identification. A Two-dimensional and Three-dimensional Topography Measurement and Correlation System was developed at the National Institute of Standards and Technology for certification of Standard Reference Material 2460/2461 bullets and cartridge cases. Based on this system, a prototype system for bullet signature measurement and correlation has been developed for bullet signature identifications, and has demonstrated superior correlation results.

  1. A facile in situ self-assembly strategy for large-scale fabrication of CHS@MOF yolk/shell structure and its catalytic application in a flow system.

    Science.gov (United States)

    Gao, Hongyi; Luan, Yi; Chaikittikul, Kullapat; Dong, Wenjun; Li, Jie; Zhang, Xiaowei; Jia, Dandan; Yang, Mu; Wang, Ge

    2015-03-04

    A hierarchical yolk/shell copper hydroxysulfates@MOF (CHS@MOF, where MOF = metal-organic frameworks) structure was fabricated from a homogeneous yolk/shell CHS template composed of an active shell and a stabilized core via a facile self-template strategy at room temperature. The active shell of the template served as the source of metal ion and was in situ transformed into a well-defined MOF crystal shell, and the relatively stabilized core retained its own nature during the formation of the MOF shell. The strategy of in situ transformation of CHS shell to MOF shell avoided the self-nucleation of MOF in the solution and complex multistep procedures. Furthermore, a flow reaction system using CHS@MOF as self-supported stationary-phase catalyst was developed, which demonstrated excellent catalytic performance for aldehyde acetalization with ethanol, and high yields and selectivities were achieved under mild conditions.

  2. Architectural constructs of Ampex DST

    Science.gov (United States)

    Johnson, Clay

    1993-01-01

    The DST 800 automated library is a high performance, automated tape storage system, developed by AMPEX, providing mass storage to host systems. Physical Volume Manager (PVM) is a volume server which supports either a DST 800, DST 600 stand alone tape drive, or a combination of DST 800 and DST 600 subsystems. The objective of the PVM is to provide the foundation support to allow automated and operator assisted access to the DST cartridges with continuous operation. A second objective is to create a data base about the media, its location, and its usage so that the quality and utilization of the media on which specific data is recorded and the performance of the storage system may be managed. The DST tape drive architecture and media provides several unique functions that enhance the ability to achieve high media space utilization and fast access. Access times are enhanced through the implementation of multiple areas (called system zones) on the media where the media may be unloaded. This reduces positioning time in loading and unloading the cartridge. Access times are also reduced through high speed positioning in excess of 800 megabytes per second. A DST cartridge can be partitioned into fixed size units which can be reclaimed for rewriting without invalidating other recorded data on the tape cartridge. Most tape management systems achieve space reclamation by deleting an entire tape volume, then allowing users to request a 'scratch tape' or 'nonspecific' volume when they wish to record data to tape. Physical cartridge sizes of 25, 75, or 165 gigabytes will make this existing process inefficient or unusable. The DST cartridge partitioning capability provides an efficient mechanism for addressing the tape space utilization problem.

  3. A novel closed cell culture device for fabrication of corneal epithelial cell sheets.

    Science.gov (United States)

    Nakajima, Ryota; Kobayashi, Toyoshige; Moriya, Noboru; Mizutani, Manabu; Kan, Kazutoshi; Nozaki, Takayuki; Saitoh, Kazuo; Yamato, Masayuki; Okano, Teruo; Takeda, Shizu

    2015-11-01

    Automation technology for cell sheet-based tissue engineering would need to optimize the cell sheet fabrication process, stabilize cell sheet quality and reduce biological contamination risks. Biological contamination must be avoided in clinical settings. A closed culture system provides a solution for this. In the present study, we developed a closed culture device called a cell cartridge, to be used in a closed cell culture system for fabricating corneal epithelial cell sheets. Rabbit limbal epithelial cells were cultured on the surface of a porous membrane with 3T3 feeder cells, which are separate from the epithelial cells in the cell cartridges and in the cell-culture inserts as a control. To fabricate the stratified cell sheets, five different thicknesses of the membranes which were welded to the cell cartridge, were examined. Multilayered corneal epithelial cell sheets were fabricated in cell cartridges that were welded to a 25 µm-thick gas-permeable membrane, which was similar to the results with the cell-culture inserts. However, stratification of corneal epithelial cell sheets did not occur with cell cartridges that were welded to 100-300 µm-thick gas-permeable membranes. The fabricated cell sheets were evaluated by histological analyses to examine the expression of corneal epithelial-specific markers. Immunohistochemical analyses showed that a putative stem cell marker, p63, a corneal epithelial differentiation maker, CK3, and a barrier function marker, Claudin-1, were expressed in the appropriate position in the cell sheets. These results suggest that the cell cartridge is effective for fabricating corneal epithelial cell sheets.

  4. Comparative evaluation of seven different sample treatment approaches for large-scale multiclass sport drug testing in urine by liquid chromatography-mass spectrometry.

    Science.gov (United States)

    Domínguez-Romero, Juan C; García-Reyes, Juan F; Molina-Díaz, Antonio

    2014-09-26

    Sample preparation is a critical step in large-scale multiclass analysis such as sport drug testing. Due to the wide heterogeneity of the analytes and the complexity of the matrix, the selection of a correct sample preparation method is essential, looking for a compromise between good recoveries for most of the analytes and cleanliness of the extract. In the present work, seven sample preparation procedures based on solid-phase extraction (SPE) (with 5 different cartridges), liquid-liquid extraction (LLE) and sorbent-supported liquid extraction (SLE) were evaluated for multiclass sport drug testing in urine. The selected SPE sorbents were polymeric cartridges Agilent PLEXA™ and Oasis HLB™, mixed mode cation and anion exchange cartridges Oasis MAX™ and MCX™, and C18 cartridges. LLE was performed using tert-butyl methyl ether and SLE was carried out using Agilent Chem Elut™ cartridges. To evaluate the proposed extraction procedures, a list of 189 compounds were selected as representative from different groups of doping agents, including 34 steroids, 14 glucocorticosteroids, 24 diuretics and masking agents, 11 stimulants, 9 beta-agonist, 16 beta-blockers, 6 Selective Estrogen Receptors Modulators (SERMs), 24 narcotics and 22 other drugs of abuse/sport drugs. Blank urine samples were spiked at two levels of concentration, 2.5 and 25μgL(-1) and extracted with the different extraction protocols (n=6). The analysis of the extracts was carried out by liquid chromatography electrospray time-of-flight mass spectrometry. The use of solid-phase extraction with polymer cartridges provided high recoveries for most of the analytes tested and was found the more suitable method for this type of application given the additional advantages such as low sample and solvent consumption along with increased automation and throughput.

  5. Enhanced Microbial Detection Capabilities by a Rapid Portable Instrument

    Science.gov (United States)

    Morris, Heather; Monaco, Lisa; Wainwright, Norm; Steele, Andrew; Damon, Michael; Schenk, Alison; Stimpson, Eric; Maule, Jake; Effinger, Michael

    2010-01-01

    We present data describing a progression of continuing technology development - from expanding the detection capabilities of the current PTS unit to re-outfitting the instrument with a protein microarray increasing the number of detectable compounds. To illustrate the adaptability of the cartridge format, on-orbit operations data from the ISS demonstrate the detection of the fungal cell wall compound beta-glucan using applicable LOCAD-PTS cartridges. LOCAD-PTS is a handheld device consisting of a spectrophotometer, an onboard pumping mechanism, and data storage capabilities. A suite of interchangeable cartridges lined with four distinct capillaries allow a hydrated sample to mix with necessary reagents in the channels before being pumped to the optical well for spectrophotometric analysis. The reagents housed in one type of cartridge trigger a reaction based on the Limulus Amebocyte Lysate (LAL) assay, which results in the release of paranitroaniline dye. The dye is measured using a 395 nm filter. The LAL assay detects the Gram-negative bacterial cell wall molecule, endotoxin or lipopolysaccharide (LPS). The more dye released, the greater the concentration of endotoxin in the sample. Sampling, quantitative analysis, and data retrieval require less than 20 minutes. This is significantly faster than standard culture-based methods, which require at least a 24 hour incubation period.Using modified cartridges, we demonstrate the detection of Gram negative bacteria with protein microarray technology. Additionally, we provide data from multiple field tests where both standard and advanced PTS technologies were used. These tests investigate the transfer of target microbial molecules from one surface to another. Collectively, these data demonstrate that the new cartridges expand the number of compounds detected by LOCAD-PTS, while maintaining the rapid, in situ analysis characteristic of the instrument. The unit provides relevant data for verifying sterile sample collection

  6. Packing Optimization of an Intentionally Stratified Sorbent Bed Containing Dissimilar Media Types

    Science.gov (United States)

    Kidd, Jessica; Guttromson, Jayleen; Holland, Nathan

    2010-01-01

    The Fire Cartridge is a packed bed air filter with two different and separate layers of media designed to provide respiratory protection from combustion products after a fire event on the International Space Station (ISS). The first layer of media is a carbon monoxide catalyst made from gold nanoparticles dispersed on iron oxide. The second layer of media is universal carbon, commonly used in commercial respirator filters. Each layer must be optimally packed to effectively remove contaminants from the air. Optimal packing is achieved by vibratory agitations. However, if post-packing movement of the media within the cartridge occurs, mixing of the bed layers, air voids, and channeling could cause preferential air flow and allow contaminants to pass. Several iterations of prototype fire cartridges were developed to reduce post-packing movement of the media within each layer (settling), and to prevent mixing of the two media types. Both types of movement of the media contribute to decreased fire cartridge performance. Each iteration of the fire cartridge design was tested to demonstrate mechanical loads required to cause detrimental movement within the bed, and resulting level of functionality of the media beds after movement was detected. In order to optimally pack each layer, vertical, horizontal, and orbital agitations were tested and a final packed bulk density was calculated for each method. Packed bulk density must be calculated for each lot of catalyst to accommodate variations in particle size, shape, and density. In addition, a physical divider sheet between each type of media was added within the fire cartridge design to further inhibit intermixing of the bed layers.

  7. Prevalence of Ex Vivo High On-treatment Platelet Reactivity on Antiplatelet Therapy after Transient Ischemic Attack or Ischemic Stroke on the PFA-100(®) and VerifyNow(®).

    LENUS (Irish Health Repository)

    Kinsella, Justin A

    2012-09-12

    BACKGROUND: The prevalence of ex vivo high on-treatment platelet reactivity (HTPR) to commonly prescribed antiplatelet regimens after transient ischemic attack (TIA) or ischemic stroke is uncertain. METHODS: Platelet function inhibition was simultaneously assessed with modified light transmission aggregometry (VerifyNow; Accumetrics Inc, San Diego, CA) and with a moderately high shear stress platelet function analyzer (PFA-100; Siemens Medical Solutions USA, Inc, Malvern, PA) in a pilot, cross-sectional study of TIA or ischemic stroke patients. Patients were assessed on aspirin-dipyridamole combination therapy (n = 51) or clopidogrel monotherapy (n = 25). RESULTS: On the VerifyNow, HTPR on aspirin was identified in 4 of 51 patients (8%) on aspirin-dipyridamole combination therapy (≥550 aspirin reaction units on the aspirin cartridge). Eleven of 25 (44%) patients had HTPR on clopidogrel (≥194 P2Y12 reaction units on the P2Y12 cartridge). On the PFA-100, 21 of 51 patients (41%) on aspirin-dipyridamole combination therapy had HTPR on the collagen-epinephrine (C-EPI) cartridge. Twenty-three of 25 patients (92%) on clopidogrel had HTPR on the collagen-adenosine diphosphate (C-ADP) cartridge. The proportion of patients with antiplatelet HTPR was lower on the VerifyNow than PFA-100 in patients on both regimens (P < .001). CONCLUSIONS: The prevalence of ex vivo antiplatelet HTPR after TIA or ischemic stroke is markedly influenced by the method used to assess platelet reactivity. The PFA-100 C-ADP cartridge is not sensitive at detecting the antiplatelet effects of clopidogrel ex vivo. Larger prospective studies with the VerifyNow and with the PFA-100 C-EPI and recently released Innovance PFA P2Y cartridges (Siemens Medical Solutions USA, Inc) in addition to newer tests of platelet function are warranted to assess whether platelet function monitoring predicts clinical outcome in ischemic cerebrovascular disease.

  8. Determination of carbonyl compounds in air by HPLC; Determinacion de compuestos carbonilicos en aire por HPLC

    Energy Technology Data Exchange (ETDEWEB)

    Garcia, S.; Perez, R.M.; Campos, A.; Gonzalez, D.

    1995-07-01

    A method for the determination of seven carbonyl compounds in air is presented. The procedure involve sampling of air by a Sep-Pak Cartridge impregnated with 2,4-dinitrophenylhydrazine. Elution was done with 3 mL of acetonitrile and the eluate was diluted to 5 mL. The analysis was done by HPLC with UV detection and external standard method quantification. It has been achieved relative standard deviations about 5% and detection limits of 80 ng/cartridge for formaldehyde, acetaldehyde and acetoacetonitrile. Three different types of samples (rural, urban, petrol emission) were successfully analyzed. (Author) 12 refs.

  9. 3D laser lithography: Quo vadis? (Conference Presentation)

    Science.gov (United States)

    Wegener, Martin

    2017-02-01

    3D printing on the macroscale is a huge trend worldwide. Ultimately, one would like to 3D print anything, including complete functional devices. Apart from boosting printing speed and pushing spatial resolution to the nanometer scale, 3D printing of many different materials poses a major challenge. In 2D graphical printers, thousands of different colors can be printed from just three color cartridges. By analogy, future 3D printers may print thousands of effective (meta-)materials from just a few materials cartridges. These metamaterials should not only be tailored in terms of their optical properties, but also electrical, magnetic, thermodynamic, mechanical, and bio-chemical.

  10. A case of suicide using a home-modified gun.

    Science.gov (United States)

    Di Nunno, Nunzio; Viola, Luigi; Colucci, Monica; Di Nunno, Cosimo; Costantinides, Fulvio

    2009-03-01

    The problem of the possibility of modifying blank cartridge dummy firearms to make them fire a real bullet has long been known, but the phenomenon has been constantly on the increase in the recent years. In Italy, there are no restrictions on the purchase of an inoffensive weapon. However, few modifications are frequently enough to transform the inoffensive weapon into a harmful one: a procedure is often undertaken to avoid the mandatory control and registration of firearms. We describe a case of suicide of a man in Trieste, Italy, in 2002, with a blank cartridge dummy pistol that had been modified to fire homemade bullets.

  11. Miniature acoustic wave lysis system and uses thereof

    Energy Technology Data Exchange (ETDEWEB)

    Branch, Darren W.; Vreeland, Erika Cooley; Smith, Gennifer Tanabe

    2016-12-06

    The present invention relates to an acoustic lysis system including a disposable cartridge that can be reversibly coupled to a platform having a small, high-frequency piezoelectric transducer array. In particular, the system releases viable DNA, RNA, and proteins from human or bacterial cells, without chemicals or additional processing, to enable high-speed sample preparation for clinical point-of-care medical diagnostics and use with nano/microfluidic cartridges. Also described herein are methods of making and using the system of the invention.

  12. Water Purification

    Science.gov (United States)

    1994-01-01

    The Vision Catalyst Purifier employs the basic technology developed by NASA to purify water aboard the Apollo spacecraft. However, it also uses an "erosion" technique. The purifier kills bacteria, viruses, and algae by "catalytic corrosion." A cartridge contains a silver-impregnated alumina bed with a large surface area. The catalyst bed converts oxygen in a pool of water to its most oxidative state, killing over 99 percent of the bacteria within five seconds. The cartridge also releases into the pool low levels of ionic silver and copper through a controlled process of erosion. Because the water becomes electrochemically active, no electricity is required.

  13. Processamento de cartuchos de impressoras de jato de tinta: um exemplo de gestão de produto pós-consumo

    Directory of Open Access Journals (Sweden)

    Felipe Pereira de Moura

    2012-01-01

    Full Text Available This work presents a route for processing spent ink-jet cartridges in an experimental course. The disassembly of the cartridges requires several steps and the recognition of their different components is essential to define the best final destination (recycling, co-processing. The plastic strips were chemically processed so as to recover gold and copper. The students recognized the difficulty of processing multicomponent wastes and the importance of the chemical work under the best safety conditions; they also experienced many laboratory techniques and recognized the value of the selective collection and the reverse logistics to reach a viable commercial scale recycling.

  14. Two-wavelength phase shift interferometry to characterize ballistic features

    Science.gov (United States)

    Pagano, Glenn W.; Mann, Christopher J.

    2014-05-01

    We apply two-wavelength phase shifting interferometry to generate 3D surface profile maps of spent bullet cartridge cases. From the captured interferograms, an optimized algorithm was used to calculate a phase profile from which a precise digital surface map of the cartridge casing may be produced. This 3D surface profile is used to enhance a firearms examiner's ability to uniquely identify distinct features or toolmarks imprinted on the casing when the weapon is fired. These features play a key role in the matching process of ballistic forensic examination.

  15. A survey of image processing techniques and statistics for ballistic specimens in forensic science.

    Science.gov (United States)

    Gerules, George; Bhatia, Sanjiv K; Jackson, Daniel E

    2013-06-01

    This paper provides a review of recent investigations on the image processing techniques used to match spent bullets and cartridge cases. It is also, to a lesser extent, a review of the statistical methods that are used to judge the uniqueness of fired bullets and spent cartridge cases. We review 2D and 3D imaging techniques as well as many of the algorithms used to match these images. We also provide a discussion of the strengths and weaknesses of these methods for both image matching and statistical uniqueness. The goal of this paper is to be a reference for investigators and scientists working in this field.

  16. Sistema limpo em linha para extração em fase sólida de contaminantes emergentes em águas naturais An in-line clean system for the solid-phase extraction of emerging contaminants in natural waters

    Directory of Open Access Journals (Sweden)

    Fernando F. Sodré

    2010-01-01

    Full Text Available A solid-phase in-line extraction system for water samples containing low levels of emerging contaminants is described. The system was specially developed for large volume samples (up to 4 L using commercial solid-phase extraction (SPE cartridges. Four sets containing PTFE-made connectors, brass adapters and ball valves were used to fit SPE cartridges and sample bottles to a 4-port manifold attached to a 20 L carboy. A lab-made vacuum device was connected to the manifold cap. The apparatus is robust and less expensive than the typical available system. Its also provides less experimental handling, avoiding cross contamination and sample losses.

  17. Nut member and mine roof support system incorporating same

    Energy Technology Data Exchange (ETDEWEB)

    Wright, R.L.

    1986-10-21

    This patent describes an improved mine roof support system including a support plate having a central opening, and an elongated rod having a leading end inserted into a drill hole behind a resin cartridge and advanced to break the cartridge and rotated to mix the components thereof to form a hardened, chemical anchor for the rod, and a trailing end of predetermined diameter from which the rod is threaded for a portion of its length. The improvement described here comprises a nut element engaged with the threaded portion of the rod.

  18. Effects of a Near Field Pyroshock on the Performance of a Nitramine Nitrocellulose Propellant

    Science.gov (United States)

    Baca, Arcenio

    2016-01-01

    The purpose of this study is to investigate the effects of a pyroshock environment on the performance characteristics of a propellant used in pyrotechnic devices such as guillotine cutters. A heritage pressure cartridge assembly which uses a nitramine nitrocellulose propellant with a known performance baseline will be exposed to a near field pyroshock event. The pressure cartridge will then be fired in an ambient closed bomb firing to collect pressure time history. This data will be compared to the baseline data to evaluate the effects of the shock on the performance of the propellant.

  19. Novel nanoporous sorbent for solid-phase extraction in petroleum fingerprinting

    Science.gov (United States)

    Alayande, S. Oluwagbemiga; Hlengilizwe, Nyoni; Dare, E. Olugbenga; Msagati, Titus A. M.; Akinlabi, A. Kehinde; Aiyedun, P. O.

    2016-04-01

    Sample preparation is crucial in the analysis of petroleum and its derivatives. In this study, developing affordable sorbent for petroleum fingerprinting analysis using polymer waste such expanded polystyrene was explored. The potential of electrospun expanded polystyrene (EPS) as a sorbent for the solid-phase extraction (SPE) technique was investigated, and its efficiency was compared with commercial cartridges such as alumina, silica and alumina/silica hybrid commercial for petroleum fingerprinting analysis. The chromatograms showed that the packed electrospun EPS fibre demonstrated excellent properties for SPE applications relative to the hybrid cartridges.

  20. TH-E-BRF-07: Raman Spectroscopy for Radiation Treatment Response Assessment in a Lung Metastases Mouse Model

    Energy Technology Data Exchange (ETDEWEB)

    Devpura, S; Barton, K; Brown, S; Siddiqui, F; Chetty, I [Henry Ford Health System, Detroit, MI (United States); Sethi, S [Karmanos Cancer Center, Detroit, MI (United States); Klein, M [Children' s Hospital of Michigan, Detroit, MI (United States)

    2014-06-15

    Purpose: Raman spectroscopy is an optical spectroscopic method used to probe chemical information about a target tissue. Our goal was to investigate whether Raman spectroscopy is able to distinguish lung tumors from normal lung tissue and whether this technique can identify the molecular changes induced by radiation. Methods: 4T1 mouse breast cancer cells were implanted subcutaneously into the flanks of 6 Balb/C female mice. Four additional mice were used as “normal lung” controls. After 14 days, 3 mice bearing tumors received 6Gy to the left lung with 6MV photons and the other three were treated as “unirradiated tumor” controls. At a 24-hour time point, lungs were excised and the specimens were sectioned using a cryostat; alternating sections were either stained with hematoxylin and eosin (H and E) for evaluation by a pathologist or unstained for Raman measurements. 240 total Raman spectra were collected; 84 from normal lung controls; 63 from unirradiated tumors and 64 from tumors irradiated with 6Gy in a single fraction. Raman spectra were also collected from normal lung tissues of mice with unirradiated tumors. Principal component analysis (PCA) and discriminant function analysis (DFA) were performed to analyze the data. Results: Raman bands assignable to DNA/RNA showed prominent contributions in tumor tissues while Raman bands associated with hemoglobin showed strong contributions in normal lung tissue. PCA/DFA analysis identified normal lung tissue and tumor with 100% and 98.4% accuracy, respectively, relative to pathologic scoring. Additionally, normal lung tissues from unirradiated mice bearing tumors were classified as normal with 100% accuracy. In a model consisting of unirradiated and irradiated tumors identification accuracy was 79.4% and 93.8% respectively, relative to pathologic assessment. Conclusion: Initial results demonstrate the promise for Raman spectroscopy in the diagnosis normal vs. lung metastases as well as the assessment of

  1. Fast and simple one-step preparation of ⁶⁸Ga citrate for routine clinical PET

    DEFF Research Database (Denmark)

    Jensen, Svend B; Nielsen, Karin M; Mewis, Dennis;

    2013-01-01

    , and the rest on the cation exchange cartridge (7.48 +/- 1.23 and in the waste vial (0.47 +/- 0.28. The radiochemical purity of the product determined by instant thin-layer chromatography was greater than 99 The products have been proven to be sterile and pyrogen-free. Variations were made in several critical...

  2. Rapid analyses of proteomes and interactomes using an integrated solid-phase extraction-liquid chromatography-MS/ms system

    NARCIS (Netherlands)

    Binai, Nadine A.; Marino, Fabio; Soendergaard, Peter; Bache, Nicolai; Mohammed, Shabaz; Heck, Albert J R

    2015-01-01

    Here, we explore applications of a LC system using disposable solid-phase extraction (SPE) cartridges and very short LC-MS/MS gradients that allows for rapid analyses in less than 10 min analysis time. The setup consists of an autosampler harboring two sets of 96 STAGE tips that function as precolum

  3. Determination of daminozide in apples and apple leaves by liquid chromatography-mass spectrometry

    NARCIS (Netherlands)

    Mol, H.G.J.; Dam, R.C.J. van; Vreeken, R.J.; Steijger, O.M.

    1999-01-01

    A straightforward and efficient method was developed for the determination of intact daminozide in apples and apple leaves. After extraction with methanol and a clean-up step using a graphitized carbon cartridge, the extract was analysed by ion-trap liquid chromatography-tandem mass spectrometry (LC

  4. High-performance liquid chromatography of rat and mouse islet polypeptides

    DEFF Research Database (Denmark)

    Linde, S; Hansen, B; Welinder, B S

    1990-01-01

    After preparative high-performance liquid chromatography of mouse islet culture medium, concentrated on disposable C18 cartridges (Sep-Pak), an unexpected insulin immunoreactive peak eluting earlier than mouse insulin I and II was detected. Molecular mass determination by mass spectrometry...

  5. 42 CFR 84.197 - Respirator containers; minimum requirements.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Respirator containers; minimum requirements. 84.197... Cartridge Respirators § 84.197 Respirator containers; minimum requirements. Respirators shall be equipped... commercial designation of the respirator it contains and all appropriate approval labels....

  6. 42 CFR 84.1158 - Dust, fume, and mist tests; respirators with filters; minimum requirements; general.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Dust, fume, and mist tests; respirators with...-Purifying High Efficiency Respirators and Combination Gas Masks § 84.1158 Dust, fume, and mist tests; respirators with filters; minimum requirements; general. (a) Three respirators with cartridges containing,...

  7. CTEPP STANDARD OPERATING PROCEDURE FOR EXTRACTING AND PREPARING AIR SAMPLES FOR ANALYSIS OF NEUTRAL PERSISTENT ORGANIC POLLUTANTS (SOP-5.12)

    Science.gov (United States)

    The method is for extracting an indoor and outdoor air sample consisting of a quartz fiber filter and an XAD-2 cartridge for analysis of neutral persistent organic pollutants. It covers the extraction and concentration of samples that are to be analyzed by gas chromatography/mass...

  8. 78 FR 44473 - Airworthiness Directives; Dassault Aviation Airplanes

    Science.gov (United States)

    2013-07-24

    ...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for all DASSAULT AVIATION Model FAN JET... cartridges, which could affect the capability to extinguish a fire in an engine, auxiliary power unit, or... Operations, M-30, West Building Ground Floor, Room W12-140, 1200 New Jersey Avenue SE., Washington, DC...

  9. Evaluative Testing of Sheep Ranching Site 5LA2316, 5LA2366, and 5LA2359 on the Pinon Canyon Maneuver Site, Las Animas County, Colorado

    Science.gov (United States)

    2009-06-01

    photographed, mapped, and bagged separately for water screening and/or flotation . Units were considered culturally sterile when the last 20 centimeters...shanks (TPQ 1830), one metal fragment, one small piece of aqua glass and a .42 caliber copper rim-fire cartridge casing manufactured by the Union Metallic

  10. 40 CFR 247.16 - Non-paper office products.

    Science.gov (United States)

    2010-07-01

    ...) Plastic trash bags. (f) Printer ribbons. (g) Plastic envelopes. (h) Plastic clipboards containing...-paper office products. (a) Office recycling containers and office waste receptacles. (b) Plastic desktop accessories. (c) Toner cartridges. (d) Plastic-covered binders containing recovered plastic; chipboard...

  11. Real time Aanderaa current meter data collection system

    Digital Repository Service at National Institute of Oceanography (India)

    AshokKumar, K.; Diwan, S.G.

    in laboratory. In this paper a method is described to read the real time current meter data and display/print/store on cartridge. For this, binary coded electrical signal available at the top end plate of the current meter is connectEd. by underwater cable...

  12. 48 CFR 3052.225-70 - Requirement for Use of Certain Domestic Commodities.

    Science.gov (United States)

    2010-10-01

    ... associated with, clothing and the materials and components thereof; or (2) Tents, tarpaulins, covers, textile... products. (2) Woven silk or woven silk blends. (3) Spun silk yarn for cartridge cloth. (4) Synthetic fabric or coated synthetic fabric (including all textile fibers and yarns that are for use in such...

  13. New Directions for Academic Video Game Collections: Strategies for Acquiring, Supporting, and Managing Online Materials

    Science.gov (United States)

    Robson, Diane; Durkee, Patrick

    2012-01-01

    The work of collection development in academic video game collections is at a crucial point of transformation--gaming librarians are ready to expand beyond console games collected in disc and cartridge format to the world of Internet games. At the same time, forms and genres of video games such as serious and independent games are increasingly…

  14. Temperature stabilization of microwave ferrite devices

    Science.gov (United States)

    Kaminsky, R.; Wendt, E. J.

    1978-01-01

    Thin-film heating element for strip-line circulator is sandwiched between insulation and copper laminations. Disks conform to shape of circulator ferrite disks and are installed between copper-clad epoxy ground planes. Heater design eliminates external cartridges and reduces weight by approximately one-third.

  15. Development of Bacterial Display Peptides for use in Biosensing Applications

    Science.gov (United States)

    2012-09-01

    Antigen of Bacillus anthracis in a Disposable Microfluidic Cartridge,” Plos One, 6(11), (2011).B. Alberts, A. Johnson, J. Lewis et al., [Molecular...RDRL SEE E J PENNINGTON ATTN RDRL SEE G WOOD ATTN RDRL SEE L BLISS ATTN RDRL SEE O J SUMNER ATTN RDRL WML B M SELLERS ADELPHI MD 20783-1197

  16. Applying Image Matching to Video Analysis

    Science.gov (United States)

    2010-09-01

    Database of Spent Cartridge Cases of Firearms". Forensic Science International . Page(s) 97-106. 2001. 21: Birchfield, S. "Derivation of Kanade-Lucas-Tomasi...Ortega-Garcia, J. "Bayesian Analysis of Fingerprint, Face and Signature Evidences with Automatic Biometric Systems". Forensic Science International . Vol

  17. Coated carbon hemoperfusion provides limited clearance of protein-bound solutes.

    Science.gov (United States)

    Dinh, Diana C; Recht, Natalie S; Hostetter, Thomas H; Meyer, Timothy W

    2008-09-01

    This study assessed the capacity of a cartridge containing coated granular carbon to clear protein-bound solutes. Clearances for test solutes were measured while an albumin solution representing plasma was pumped from a 10 L reservoir through the cartridge at a rate of 200 mL/min for 5 h. Clearance values for phenol red, phenytoin, and indican were well below the limit imposed by the plasma flow and declined with time. The clearance of phenol red, which was the most tightly bound solute, fell from 38 +/- 12 to 17 +/- 2 mL/min. Additional studies revealed that the cartridge contained enough carbon to absorb all the protein-bound test solutes, but that the rate of their clearance was limited by the inability of granular carbon to take up solutes rapidly at a low concentration. The rate of solute uptake at low concentration was shown to be much greater when carbon was in powdered rather than granular form. A device in which approximately 50 g of powdered carbon was recirculated in the dialysate compartment of hollow fiber kidneys cleared phenol red and phenytoin more rapidly than the hemoperfusion cartridge containing 300 g of coated granular carbon. These results indicate that hemoperfusion over coated granular carbon provides limited clearance of protein-bound solutes.

  18. Aircraft Carrier Flight and Hangar Deck Fire Protection: History and Current Status

    Science.gov (United States)

    2005-01-01

    authorized provided the rack is electrically disconnected and either the mechanical safety pin is installed or the IFOBRL mechanism is locked. FIGURE 40...cartridges may remain in the BRU-9/-10/-11 ejector bomb rack provided the rack is electrically disconnected and either the mechanical safety pin is

  19. Model Analysis and Expert System Development for Planning and Scheduling Teleoperations for Aircraft Turnaround Functions. Volume 1

    Science.gov (United States)

    1992-02-01

    the function A (Mk-82) for example. The subtasks are: 1. Install impulse cartridges. 2. Position and load munitions. 3. Install rack safety pin . 4...Remove fin release band safety pin . Each of these tasks may have micro subtasks. Associated with each of these tasks are resources (known as crews) and

  20. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT: STORMWATER MANAGEMENT STORMFILTER® TREATMENT SYSTEM USING PERLITE MEDIA

    Science.gov (United States)

    Verification testing of the Stormwater Management, Inc. StormFilter® Using Perlite Filter Media was conducted on a 0.7 acre drainage basin near downtown Griffin, Georgia. The system consists of an inlet bay, flow spreader, cartridge bay, overflow baffle, and outlet bay, housed in...