WorldWideScience

Sample records for unexpectedly high levels

  1. Unexpected high plasma cobalamin

    DEFF Research Database (Denmark)

    Arendt, Johan F B; Nexo, Ebba

    2013-01-01

    It is well-established that more than 8% of patients examined for vitamin B12 deficiency unexpectedly have increased plasma levels of the vitamin, but so far there are no guidelines for the clinical interpretation of such findings. In this review, we summarise known associations between high plasma...... cobalamin binding proteins, transcobalamin and haptocorrin. Based on current knowledge, we suggest a strategy for the clinical interpretation of unexpected high plasma cobalamin. Since a number of the associated diseases are critical and life-threatening, the strategy promotes the concept of 'think...

  2. Unexpected levels and movement of radon in a large warehouse

    International Nuclear Information System (INIS)

    Gammage, R.B.; Espinosa, G.

    2004-01-01

    Alpha-track detectors, used in screening for radon, identified a large warehouse with levels of radon as high as 20 p Ci/l. This circumstance was unexpected because large bay doors were left open for much of the day to admit 1 8-wheeler trucks, and exhaust fans in the roof produced good ventilation. More detailed temporal and spatial investigations of radon and air-flow patterns were made with electret chambers, Lucas-cell flow chambers, tracer gas, smoke pencils and pressure sensing micrometers. An oval-dome shaped zone of radon (>4 p Ci/L) persisted in the central region of each of four separate bays composing the warehouse. Detailed studies of air movement in the bay with the highest levels of radon showed clockwise rotation of air near the outer walls with a central dead zone. Sub slab, radon-laden air ingresses the building through expansion joints between the floor slabs to produce the measured radon. The likely source of radon is air within porous, karst bedrock that underlies much of north-central Tennessee where the warehouse is situated

  3. New product trial, use of edibles, and unexpected highs among marijuana and hashish users in Colorado.

    Science.gov (United States)

    Allen, Jane A; Davis, Kevin C; Duke, Jennifer C; Nonnemaker, James M; Bradfield, Brian R; Farrelly, Matthew C

    2017-07-01

    This study examines the relationships between trial of new marijuana or hashish products and unexpected highs, and use of edible products and unexpected highs. We conducted an online survey of 634 adult, past-year marijuana users in Colorado. We used logistic regression models to examine the relationship between new product trial or edible use and unexpected highs. In the first year that recreational marijuana was legal in Colorado, 71.4% of respondents tried a new marijuana or hashish product, and 53.6% used an edible product. Trial of new products was associated with greater odds of experiencing an unexpected high after controlling for age, gender, education, mental health status, current marijuana or hashish use, and mean amount of marijuana or hashish consumed in the past month (OR=2.13, pmarijuana or hashish products, or use edible marijuana or hashish products, are at greater risk for an unexpected high. It is possible that some negative outcomes associated with marijuana use and unexpected highs may be averted through a better understanding of how to use product packaging to communicate with consumers. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. Unexpectedly High Levels of Cryptic Diversity Uncovered by a Complete DNA Barcoding of Reptiles of the Socotra Archipelago.

    Science.gov (United States)

    Vasconcelos, Raquel; Montero-Mendieta, Santiago; Simó-Riudalbas, Marc; Sindaco, Roberto; Santos, Xavier; Fasola, Mauro; Llorente, Gustavo; Razzetti, Edoardo; Carranza, Salvador

    2016-01-01

    Few DNA barcoding studies of squamate reptiles have been conducted. Due to the significance of the Socotra Archipelago (a UNESCO Natural World Heritage site and a biodiversity hotspot) and the conservation interest of its reptile fauna (94% endemics), we performed the most comprehensive DNA barcoding study on an island group to date to test its applicability to specimen identification and species discovery. Reptiles constitute Socotra's most important vertebrate fauna, yet their taxonomy remains under-studied. We successfully DNA-barcoded 380 individuals of all 31 presently recognized species. The specimen identification success rate is moderate to high, and almost all species presented local barcoding gaps. The unexpected high levels of intra-specific variability found within some species suggest cryptic diversity. Species richness may be under-estimated by 13.8-54.4%. This has implications in the species' ranges and conservation status that should be considered for conservation planning. Other phylogenetic studies using mitochondrial and nuclear markers are congruent with our results. We conclude that, despite its reduced length (663 base pairs), cytochrome c oxidase 1, COI, is very useful for specimen identification and for detecting intra-specific diversity, and has a good phylogenetic signal. We recommend DNA barcoding to be applied to other biodiversity hotspots for quickly and cost-efficiently flagging species discovery, preferentially incorporated into an integrative taxonomic framework.

  5. Unexpectedly High Levels of Cryptic Diversity Uncovered by a Complete DNA Barcoding of Reptiles of the Socotra Archipelago.

    Directory of Open Access Journals (Sweden)

    Raquel Vasconcelos

    Full Text Available Few DNA barcoding studies of squamate reptiles have been conducted. Due to the significance of the Socotra Archipelago (a UNESCO Natural World Heritage site and a biodiversity hotspot and the conservation interest of its reptile fauna (94% endemics, we performed the most comprehensive DNA barcoding study on an island group to date to test its applicability to specimen identification and species discovery. Reptiles constitute Socotra's most important vertebrate fauna, yet their taxonomy remains under-studied. We successfully DNA-barcoded 380 individuals of all 31 presently recognized species. The specimen identification success rate is moderate to high, and almost all species presented local barcoding gaps. The unexpected high levels of intra-specific variability found within some species suggest cryptic diversity. Species richness may be under-estimated by 13.8-54.4%. This has implications in the species' ranges and conservation status that should be considered for conservation planning. Other phylogenetic studies using mitochondrial and nuclear markers are congruent with our results. We conclude that, despite its reduced length (663 base pairs, cytochrome c oxidase 1, COI, is very useful for specimen identification and for detecting intra-specific diversity, and has a good phylogenetic signal. We recommend DNA barcoding to be applied to other biodiversity hotspots for quickly and cost-efficiently flagging species discovery, preferentially incorporated into an integrative taxonomic framework.

  6. Unexpected nitrile formation in bio-based mesoporous materials (Starbons®).

    Science.gov (United States)

    Attard, Jennifer; Milescu, Roxana; Budarin, Vitaliy; Matharu, Avtar S; Clark, James H

    2018-01-16

    The bio-based mesoporous materials made from polysaccharides, Starbons® can be modified by two different routes to give high levels of N-content, unexpectedly including significant quantities of nitrile groups which can improve the materials performance in applications including metal capture.

  7. The unexpected stability of multiwall nanotubes under high pressure and shear deformation

    International Nuclear Information System (INIS)

    Pashkin, E. Y.; Pankov, A. M.; Kulnitskiy, B. A.; Mordkovich, V. Z.; Perezhogin, I. A.; Karaeva, A. R.; Popov, M. Y.; Sorokin, P. B.; Blank, V. D.

    2016-01-01

    The behavior of multiwall carbon nanotubes under a high pressure (up to 55 GPa) combined with shear deformation was studied by experimental and theoretical methods. The unexpectedly high stability of the nanotubes' structure under high stresses was observed. After the pressure was released, we observed that the nanotubes had restored their shapes. Atomistic simulations show that the hydrostatic and shear stresses affect the nanotubes' structure in a different way. It was found that the shear stress load in the multiwall nanotubes' outer walls can induce their connection and formation of an amorphized sp"3-hybridized region but internal core keeps the tubular structure.

  8. The unexpected stability of multiwall nanotubes under high pressure and shear deformation

    Energy Technology Data Exchange (ETDEWEB)

    Pashkin, E. Y.; Pankov, A. M.; Kulnitskiy, B. A.; Mordkovich, V. Z. [Technological Institute for Superhard and Novel Carbon Materials, 7a Centralnaya Street, Troitsk, Moscow 142190 (Russian Federation); Moscow Institute of Physics and Technology, 9 Institutsky Lane, Dolgoprudny 141700 (Russian Federation); Perezhogin, I. A. [Technological Institute for Superhard and Novel Carbon Materials, 7a Centralnaya Street, Troitsk, Moscow 142190 (Russian Federation); Lomonosov Moscow State University, Leninskie Gory, Moscow 119991 (Russian Federation); Karaeva, A. R. [Technological Institute for Superhard and Novel Carbon Materials, 7a Centralnaya Street, Troitsk, Moscow 142190 (Russian Federation); Popov, M. Y.; Sorokin, P. B.; Blank, V. D. [Technological Institute for Superhard and Novel Carbon Materials, 7a Centralnaya Street, Troitsk, Moscow 142190 (Russian Federation); Moscow Institute of Physics and Technology, 9 Institutsky Lane, Dolgoprudny 141700 (Russian Federation); National University of Science and Technology MISiS, 4 Leninskiy Prospekt, Moscow 119049 (Russian Federation)

    2016-08-22

    The behavior of multiwall carbon nanotubes under a high pressure (up to 55 GPa) combined with shear deformation was studied by experimental and theoretical methods. The unexpectedly high stability of the nanotubes' structure under high stresses was observed. After the pressure was released, we observed that the nanotubes had restored their shapes. Atomistic simulations show that the hydrostatic and shear stresses affect the nanotubes' structure in a different way. It was found that the shear stress load in the multiwall nanotubes' outer walls can induce their connection and formation of an amorphized sp{sup 3}-hybridized region but internal core keeps the tubular structure.

  9. Unexpectedly high catch-and-release rates in European marine recreational fisheries: implications for science and management

    DEFF Research Database (Denmark)

    Ferter, Keno; Weltersbach, Marc Simon; Strehlow, Harry Vincent

    2013-01-01

    Unexpectedly high catch-and-release rates in European marine recreational fisheries: implications for science and management. – ICES Journal of Marine Science, 70: .While catch-and-release (C&R) is a well-known practice in several European freshwater recreational fisheries, studies on the magnitu...

  10. Autistic Traits Affect P300 Response to Unexpected Events, regardless of Mental State Inferences

    Directory of Open Access Journals (Sweden)

    Mitsuhiko Ishikawa

    2017-01-01

    Full Text Available Limited use of contextual information has been suggested as a way of understanding cognition in people with autism spectrum disorder (ASD. However, it has also been argued that individuals with ASD may have difficulties inferring others’ mental states. Here, we examined how individuals with different levels of autistic traits respond to contextual deviations by measuring event-related potentials that reflect context usage. The Autism Spectrum Quotient (AQ was used to quantify autistic-like traits in 28 university students, and 19 participants were defined as Low or High AQ groups. To additionally examine inferences about mental state, two belief conditions (with or without false belief were included. Participants read short stories in which the final sentence included either an expected or an unexpected word and rated the word’s degree of deviation from expectation. P300 waveform analysis revealed that unexpected words were associated with larger P300 waveforms for the Low AQ group, but smaller P300 responses in the High AQ group. Additionally, AQ social skill subscores were positively correlated with evaluation times in the Unexpected condition, whether a character’s belief was false or not. This suggests that autistic traits can affect responses to unexpected events, possibly because of decreased availability of context information.

  11. Structural imaging biomarkers of sudden unexpected death in epilepsy.

    Science.gov (United States)

    Wandschneider, Britta; Koepp, Matthias; Scott, Catherine; Micallef, Caroline; Balestrini, Simona; Sisodiya, Sanjay M; Thom, Maria; Harper, Ronald M; Sander, Josemir W; Vos, Sjoerd B; Duncan, John S; Lhatoo, Samden; Diehl, Beate

    2015-10-01

    Sudden unexpected death in epilepsy is a major cause of premature death in people with epilepsy. We aimed to assess whether structural changes potentially attributable to sudden death pathogenesis were present on magnetic resonance imaging in people who subsequently died of sudden unexpected death in epilepsy. In a retrospective, voxel-based analysis of T1 volume scans, we compared grey matter volumes in 12 cases of sudden unexpected death in epilepsy (two definite, 10 probable; eight males), acquired 2 years [median, interquartile range (IQR) 2.8] before death [median (IQR) age at scanning 33.5 (22) years], with 34 people at high risk [age 30.5 (12); 19 males], 19 at low risk [age 30 (7.5); 12 males] of sudden death, and 15 healthy controls [age 37 (16); seven males]. At-risk subjects were defined based on risk factors of sudden unexpected death in epilepsy identified in a recent combined risk factor analysis. We identified increased grey matter volume in the right anterior hippocampus/amygdala and parahippocampus in sudden death cases and people at high risk, when compared to those at low risk and controls. Compared to controls, posterior thalamic grey matter volume, an area mediating oxygen regulation, was reduced in cases of sudden unexpected death in epilepsy and subjects at high risk. The extent of reduction correlated with disease duration in all subjects with epilepsy. Increased amygdalo-hippocampal grey matter volume with right-sided changes is consistent with histo-pathological findings reported in sudden infant death syndrome. We speculate that the right-sided predominance reflects asymmetric central influences on autonomic outflow, contributing to cardiac arrhythmia. Pulvinar damage may impair hypoxia regulation. The imaging findings in sudden unexpected death in epilepsy and people at high risk may be useful as a biomarker for risk-stratification in future studies. The Author (2015). Published by Oxford University Press on behalf of the Guarantors of

  12. Cluster-level statistical inference in fMRI datasets: The unexpected behavior of random fields in high dimensions.

    Science.gov (United States)

    Bansal, Ravi; Peterson, Bradley S

    2018-06-01

    Identifying regional effects of interest in MRI datasets usually entails testing a priori hypotheses across many thousands of brain voxels, requiring control for false positive findings in these multiple hypotheses testing. Recent studies have suggested that parametric statistical methods may have incorrectly modeled functional MRI data, thereby leading to higher false positive rates than their nominal rates. Nonparametric methods for statistical inference when conducting multiple statistical tests, in contrast, are thought to produce false positives at the nominal rate, which has thus led to the suggestion that previously reported studies should reanalyze their fMRI data using nonparametric tools. To understand better why parametric methods may yield excessive false positives, we assessed their performance when applied both to simulated datasets of 1D, 2D, and 3D Gaussian Random Fields (GRFs) and to 710 real-world, resting-state fMRI datasets. We showed that both the simulated 2D and 3D GRFs and the real-world data contain a small percentage (<6%) of very large clusters (on average 60 times larger than the average cluster size), which were not present in 1D GRFs. These unexpectedly large clusters were deemed statistically significant using parametric methods, leading to empirical familywise error rates (FWERs) as high as 65%: the high empirical FWERs were not a consequence of parametric methods failing to model spatial smoothness accurately, but rather of these very large clusters that are inherently present in smooth, high-dimensional random fields. In fact, when discounting these very large clusters, the empirical FWER for parametric methods was 3.24%. Furthermore, even an empirical FWER of 65% would yield on average less than one of those very large clusters in each brain-wide analysis. Nonparametric methods, in contrast, estimated distributions from those large clusters, and therefore, by construct rejected the large clusters as false positives at the nominal

  13. Managing the nation's commercial high-level radioactive waste

    International Nuclear Information System (INIS)

    1985-03-01

    This report presents the findings and conclusions of OTA's analysis of Federal policy for the management of commercial high-level radioactive waste. It is intended to contribute to the implementation of Nuclear Waste Policy Act of 1982 (NWPA). The major conclusion of that review is that NWPA provides sufficient authority for developing and operating a waste management system based on disposal in geologic repositories. Substantial new authority for other facilities will not be required unless major unexpected problems with geologic disposal are encountered. OTA also concludes that DOE's Draft Mission Plan published in 1984 falls short of its potential for enhancing the credibility and acceptability of the waste management program

  14. Unexpected high-energy γ emission from decaying exotic nuclei

    Directory of Open Access Journals (Sweden)

    A. Gottardo

    2017-09-01

    Full Text Available The N=52 Ga83 β decay was studied at ALTO. The radioactive 83Ga beam was produced through the ISOL photofission technique and collected on a movable tape for the measurement of γ-ray emission following β decay. While β-delayed neutron emission has been measured to be 56–85% of the decay path, in this experiment an unexpected high-energy 5–9 MeV γ-ray yield of 16(4% was observed, coming from states several MeVs above the neutron separation threshold. This result is compared with cutting-edge QRPA calculations, which show that when neutrons deeply bound in the core of the nucleus decay into protons via a Gamow–Teller transition, they give rise to a dipolar oscillation of nuclear matter in the nucleus. This leads to large electromagnetic transition probabilities which can compete with neutron emission, thus affecting the β-decay path. This process is enhanced by an excess of neutrons on the nuclear surface and may thus be a common feature for very neutron-rich isotopes, challenging the present understanding of decay properties of exotic nuclei.

  15. The accrual anomaly - focus on changes in specific unexpected accruals results in new evidence

    DEFF Research Database (Denmark)

    Schøler, Finn

    are specifically analyzed, namely the unexpected inventory accrual component and the unexpected accounts receivable accrual component, i.e. changes in accruals not motivated by corresponding changes in company activity-level. Additionally and for comparison, the accounting accruals are split into expected...... and unexpected accruals, estimated by the extended Jones model like in both some US-analyses and some international studies of the accrual anomaly phenomenon. It is found that the persistence of earnings is decreasing in the magnitude of the unexpected accrual components of earnings and that the persistence...... of current earnings performance is particularly decreasing in the magnitude of unexpected changes in inventory. The special accrual parts are related to the perceptions of earnings persistence implicit in the market prices, and it is found that the differences in earnings persistence are not rationally...

  16. [Development of the unexpected reality scale for childcare training].

    Science.gov (United States)

    Matsuda, Yuko; Shitara, Saeko; Hamada, Shoko

    2016-10-01

    This study aimed to develop a scale for unexpected reality for childcare training (Study 1) and examine the change and influence it exerts on the efficacy of preschool teachers (Study 2). In Study 1, the sample consisted of 571 university and junior college students enrolled in a childcare course. After exploratory factor analysis, four factors were extracted: “actual feelings for childcare as a field of study,” “difficulties faced during involvement with children,” “negative aspects of the childcare worker,” and “severity of work.” The study’s scale was shown to be internally consistent and valid. In Study 2, the sample consisted of 122 junior college students enrolled in a childcare course. The results showed that the high-scoring groups of each unexpected reality subscales experienced less unexpected reality in the subsequent training session. Moreover, the results of multiple regression showed that preschool teacher efficacy was predicted positively by “actual feelings for childcare as a field of study” and negatively by “difficulties faced during involvement with children.” Thus, we suggest that for effective pre- and post-guidance of childcare training, unexpected realities should be considered.

  17. Unexpected uncertainty, volatility and decision-making

    Directory of Open Access Journals (Sweden)

    Amy Rachel Bland

    2012-06-01

    Full Text Available The study of uncertainty in decision making is receiving greater attention in the fields of cognitive and computational neuroscience. Several lines of evidence are beginning to elucidate different variants of uncertainty. Particularly, risk, ambiguity and expected and unexpected forms of uncertainty are well articulated in the literature. In this article we review both empirical and theoretical evidence arguing for the potential distinction between three forms of uncertainty; expected uncertainty, unexpected uncertainty and volatility. Particular attention will be devoted to exploring the distinction between unexpected uncertainty and volatility which has been less appreciated in the literature. This includes evidence from computational modelling, neuromodulation, neuroimaging and electrophysiological studies. We further address the possible differentiation of cognitive control mechanisms used to deal with these forms of uncertainty. Particularly we explore a role for conflict monitoring and the temporal integration of information into working memory. Finally, we explore whether the Dual Modes of Control theory provides a theoretical framework for understanding the distinction between unexpected uncertainty and volatility.

  18. Theory of mind for processing unexpected events across contexts.

    Science.gov (United States)

    Dungan, James A; Stepanovic, Michael; Young, Liane

    2016-08-01

    Theory of mind, or mental state reasoning, may be particularly useful for making sense of unexpected events. Here, we investigated unexpected behavior across both social and non-social contexts in order to characterize the precise role of theory of mind in processing unexpected events. We used functional magnetic resonance imaging to examine how people respond to unexpected outcomes when initial expectations were based on (i) an object's prior behavior, (ii) an agent's prior behavior and (iii) an agent's mental states. Consistent with prior work, brain regions for theory of mind were preferentially recruited when people first formed expectations about social agents vs non-social objects. Critically, unexpected vs expected outcomes elicited greater activity in dorsomedial prefrontal cortex, which also discriminated in its spatial pattern of activity between unexpected and expected outcomes for social events. In contrast, social vs non-social events elicited greater activity in precuneus across both expected and unexpected outcomes. Finally, given prior information about an agent's behavior, unexpected vs expected outcomes elicited an especially robust response in right temporoparietal junction, and the magnitude of this difference across participants correlated negatively with autistic-like traits. Together, these findings illuminate the distinct contributions of brain regions for theory of mind for processing unexpected events across contexts. © The Author (2016). Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com.

  19. Nationwide survey of rotavirus-associated encephalopathy and sudden unexpected death in Japan.

    Science.gov (United States)

    Kawamura, Yoshiki; Ohashi, Masahiro; Ihira, Masaru; Hashimoto, Shuji; Taniguchi, Koki; Yoshikawa, Tetsushi

    2014-08-01

    Rotavirus can cause severe complications such as encephalopathy/encephalitis and sudden unexpected death. The incidence of rotavirus-associated encephalopathy/encephalitis or sudden unexpected death remains unknown. To clarify the clinical features of rotavirus-associated encephalitis/encephalopathy and sudden unexpected death, we conducted a nationwide survey in Japan. A two-part questionnaire was designed to determine the number of the cases and the clinical features of severe cases of rotavirus infection, including encephalitis/encephalopathy and sudden unexpected death, between 2009 and 2011. Of the 1365 questionnaires sent to hospitals, 963 (70.5%) were returned and eligible for analysis. We determined 58 cases of rotavirus-associated encephalitis/encephalopathy and 7 cases of sudden unexpected death. These patients were diagnosed with rotavirus infection by immunochromatography. Although 36/58 (62.1%) encephalitis/encephalopathy patients had no sequelae, 15/58 (25.9%) patients had neurological sequelae, and 7/58 (12.1%) patients had fatal outcomes. Pleocytosis was observed in 9/40 (22.5%) patients and cerebrospinal fluid protein levels were elevated in only 4/40 (10%) patients. Elevated lactate dehydrogenase (LDH) (>500 IU/L) or acidemia (pHdeath were 44.0 and 4.9 cases in Japan, respectively. Elevated LDH (>500 IU/L) or acidemia (pH<7.15) were related to a poor prognosis of the encephalitis/encephalopathy. Copyright © 2013 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.

  20. Gastrointestinal causes of sudden unexpected death: A review.

    Science.gov (United States)

    Menezes, Ritesh G; Ahmed, Saba; Pasha, Syed Bilal; Hussain, Syed Ather; Fatima, Huda; Kharoshah, Magdy A; Madadin, Mohammed

    2018-01-01

    Gastrointestinal conditions are a less common cause of sudden unexpected death when compared to other conditions such as cardiovascular conditions, but they are equally important. Various congenital and acquired gastrointestinal conditions that have resulted in sudden unexpected death are discussed. The possible lethal mechanisms behind each condition, along with any associated risk factors or secondary diseases, have been described. Through this article, we aim to highlight the need for physicians to prevent death in such conditions by ensuring that subclinical cases are diagnosed correctly before it is too late and by providing timely and efficacious treatment to the patient concerned. In addition, this review would certainly benefit the forensic pathologist while dealing with cases of sudden unexpected death due to gastrointestinal causes. This article is a review of the major gastrointestinal causes of sudden unexpected death. In addition, related fatal cases encountered occasionally in forensic autopsy practice are also included. There are several unusual and rare causes of life-threatening gastrointestinal bleeding that may lead to sudden unexpected death to cover all the entities in detail. Nevertheless, this article is a general guide to the topic of gastrointestinal causes of sudden unexpected death.

  1. Circadian variation in unexpected postoperative death

    DEFF Research Database (Denmark)

    Rosenberg, J; Pedersen, M H; Ramsing, T

    1992-01-01

    Unexpected deaths still occur following major surgical procedures. The cause is often unknown but may be cardiac or thromboembolic in nature. Postoperative ischaemia, infarction and sudden cardiac death may be triggered by episodic or constant arterial hypoxaemia, which increases during the night...... deaths occurred at night-time. These results suggest a need for further studies of sleep- and respiration-related effects on postoperative nocturnal cardiac function. The efficacy of monitoring during this apparent high-risk period should be evaluated....

  2. Mammalian play: training for the unexpected.

    Science.gov (United States)

    Spinka, M; Newberry, R C; Bekoff, M

    2001-06-01

    In this review, we present a new conceptual framework for the study of play behavior, a hitherto puzzling array of seemingly purposeless and unrelated behavioral elements that are recognizable as play throughout the mammalian lineage. Our major new functional hypothesis is that play enables animals to develop flexible kinematic and emotional responses to unexpected events in which they experience a sudden loss of control. Specifically, we propose that play functions to increase the versatility of movements used to recover from sudden shocks such as loss of balance and falling over, and to enhance the ability of animals to cope emotionally with unexpected stressful situations. To obtain this "training for the unexpected," we suggest that animals actively seek and create unexpected situations in play through self-handicapping; that is, deliberately relaxing control over their movements or actively putting themselves into disadvantageous positions and situations. Thus, play is comprised of sequences in which the players switch rapidly between well-controlled movements similar to those used in "serious" behavior and self-handicapping movements that result in temporary loss of control. We propose that this playful switching between in-control and out-of-control elements is cognitively demanding, setting phylogenetic and ontogenetic constraints on play, and is underlain by neuroendocrinological responses that produce a complex emotional state known as "having fun." Furthermore, we propose that play is often prompted by relatively novel or unpredictable stimuli, and is thus related to, although distinct from, exploration. We present 24 predictions that arise from our new theoretical framework, examining the extent to which they are supported by the existing empirical evidence and contrasting them with the predictions of four major alternative hypotheses about play. We argue that our "training for the unexpected" hypothesis can account for some previously puzzling

  3. Unexpected allergic reactions to food, a prospective study

    NARCIS (Netherlands)

    Michelsen-Huisman, A.D.; Os-Medendorp, H. van; Versluis, A.; Kruizinga, A.G.; Castenmiller, J.J.M.; Noteborn, H.P.J.M.; Houben, G.F.; Knulst, A.C.

    2013-01-01

    Unexpected reactions occur in patients with food allergy, but frequency data are scare. This prospective study investigates the frequency, severity and causes of unexpected allergic reactions to food in adults with a doctor's diagnosed food allergy. Participants complete an online questionnaire

  4. Psychological stress in high level sailors during competition

    Directory of Open Access Journals (Sweden)

    Luciana Segato

    2010-09-01

    Full Text Available The purpose of this work was to investigate the psychological stress present in elite sailors in a competition. Based on a descriptive field research, 31 elite sailors volunteered to participate. They answered the Perceived Stress Scale (Cohen & Williamson, 1988 and also specific questions on self-control, sources and strategies of coping. Data were analyzed by using descriptive and inferential (Student t test and Pearson's correlation statistics. These athletes revealed low and moderate scores (M = 20.00, DP = 6.83 of stress originated from both intrinsic (ship troubles, team disorders and extrinsic (study, working and training, family and financial problems sources. The group reported good stress control during competition through the use of cognitive (avoidance and somatic (listening music, resting/sleeping, talk to friends strategies. It is important that sailors are able to control and cope with high levels of psychological stress and to understand how to proceed when under unstable and unexpected situations that arise during competition.

  5. Psychological stress in high level sailors during competition

    Directory of Open Access Journals (Sweden)

    L. Segato

    2010-01-01

    Full Text Available The purpose of this work was to investigate the psychological stress present in elite sailors in a competition. Based on a descriptive field research, 31 elite sailors volunteered to participate. They answered the Perceived Stress Scale (Cohen & Williamson, 1988 and also specific questions on self-control, sources and strategies of coping. Data were analyzed by using descriptive and inferential (Student t test and Pearson's correlation statistics. These athletes revealed low and moderate scores (M = 20.00, DP = 6.83 of stress originated from both intrinsic (ship troubles, team disorders and extrinsic (study, working and training, family and financial problems sources. The group reported good stress control during competition through the use of cognitive (avoidance and somatic (listening music, resting/sleeping, talk to friends strategies. It is important that sailors are able to control and cope with high levels of psychological stress and to understand how to proceed when under unstable and unexpected situations that arise during competition.

  6. Unexpected High Sensory Blockade during Continuous Spinal Anesthesiology (CSA in an Elderly Patient

    Directory of Open Access Journals (Sweden)

    R. Ketelaars

    2012-01-01

    Full Text Available A 98-year-old woman presented for a hemiarthroplasty of the left hip. Because of her age and cardiac and pulmonary co-existing diseases we decided to provide adequate regional anesthesia by continuous spinal anesthesia. Fragmented doses of isobaric bupivacaine 0.5% were administered through a system consisting of a spinal catheter connected to an antimicrobial filter. After an uneventful surgical procedure, prior to removal of the catheter, this system was flushed with 10 mL of normal saline in order to try to prevent post-dural-puncture headache. After arrival at the postanesthesia care unit and fifteen minutes after removal of the catheter the patient suffered an unexpected high thoracic sensory blockade and hypotension requiring treatment. The continuous spinal anesthesia technique can be used in selected cases to be able to administer local anesthetic agents in a slow and controlled manner to reach the desired effect. The risk of post-dural-puncture headache using this technique in elderly patients is very low and therefore precludes the need to try to prevent it. We have described a potentially dangerous complication of flushing a bupivacaine-filled system into the spinal canal of an elderly patient resulting in an undesirable high sensory blockade.

  7. Unexpectedly high piezoelectricity of Sm-doped lead zirconate titanate in the Curie point region.

    Science.gov (United States)

    Seshadri, Shruti B; Nolan, Michelle M; Tutuncu, Goknur; Forrester, Jennifer S; Sapper, Eva; Esteves, Giovanni; Granzow, Torsten; Thomas, Pam A; Nino, Juan C; Rojac, Tadej; Jones, Jacob L

    2018-03-07

    Large piezoelectric coefficients in polycrystalline lead zirconate titanate (PZT) are traditionally achieved through compositional design using a combination of chemical substitution with a donor dopant and adjustment of the zirconium to titanium compositional ratio to meet the morphotropic phase boundary (MPB). In this work, a different route to large piezoelectricity is demonstrated. Results reveal unexpectedly high piezoelectric coefficients at elevated temperatures and compositions far from the MPB. At temperatures near the Curie point, doping with 2 at% Sm results in exceptionally large piezoelectric coefficients of up to 915 pm/V. This value is approximately twice those of other donor dopants (e.g., 477 pm/V for Nb and 435 pm/V for La). Structural changes during the phase transitions of Sm-doped PZT show a pseudo-cubic phase forming ≈50 °C below the Curie temperature. Possible origins of these effects are discussed and the high piezoelectricity is posited to be due to extrinsic effects. The enhancement of the mechanism at elevated temperatures is attributed to the coexistence of tetragonal and pseudo-cubic phases, which enables strain accommodation during electromechanical deformation and interphase boundary motion. This work provides insight into possible routes for designing high performance piezoelectrics which are alternatives to traditional methods relying on MPB compositions.

  8. An unexpected pulmonary bystander

    NARCIS (Netherlands)

    Wouthuyzen-Bakker, M.; Vorm, van der P. A.; Koning, K. J.; van der Werf, T. S.

    A 30-year-old man from Eritrea was admitted with a pulmonary bacterial abscess. Unexpectedly, histopathology of the resected lobe also revealed an infection with Schistosoma mansoni with surrounding granulomatous tissue and fibrosis. Patients from endemic areas are often asymptomatic with blood

  9. Unexpected pathological findings after laparoscopic cholecystectomy - analysis of 1131 cases.

    Science.gov (United States)

    Bartosiak, Katarzyna; Liszka, Maciej; Drazba, Tomasz; Paśnik, Krzysztof; Janik, Michal R

    2018-03-01

    Gallbladder specimens are routinely sent for histopathological examination after cholecystectomy in order to rule out the presence of unexpected pathological findings. To establish the overall incidence of unexpected pathological findings in patients who underwent laparoscopic cholecystectomy for symptomatic gallbladder disease and determine whether the macroscopic appearance of the gallbladder in ultrasound examination could be a valid method for identifying patients with gallbladder malignancy. A retrospective study was conducted between 2013 and 2015. All histological reports (n = 1131) after cholecystectomy were searched for unexpected pathological findings. In cases where unexpected pathological findings were identified the additional analysis of preoperative abdominal ultrasound examination (USG) was done to determine the usefulness of USG in diagnosis of gallbladder malignancy. Of the 1131 patients included in the study, 356 (31.47%) were male and 774 (68.43%) were female. Unexpected pathological findings were present in 21 cases. The overall incidence of unexpected pathological findings was 1.86%. Only in 5 patients were suspicious appearances of gallbladder observed in preoperative ultrasound examination. In 16 patients there was no suspicion of malignancy. The positive predictive value of USG was 0.238. The incidence of unexpected pathological findings after laparoscopic cholecystectomy was 1.86%. Ultrasonography has low positive predictive value for identifying patients with malignant findings in a gallbladder specimen.

  10. 42 CFR 493.861 - Standard; Unexpected antibody detection.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Standard; Unexpected antibody detection. 493.861 Section 493.861 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN..., Or Any Combination of These Tests § 493.861 Standard; Unexpected antibody detection. (a) Failure to...

  11. Training to handle unexpected events

    International Nuclear Information System (INIS)

    Hamlin, K.W.

    1987-01-01

    The importance of conducting hands-on training to deal with complex situations is well recognized. Since most utilities now own or have ordered their own control room simulators, access to simulator training facilities has improved greatly. Most utilities now have a control room shift rotation that includes a dedicated training shift. The opportunities for practicing operational control over unexpected and off-normal events are just beginning to be recognized. Areas that are being enhanced include teamwork training, diagnostics training, expanded simulator training programs, improvements in simulator instructor training, emergency procedures training, and training on the use of probabilistic risk assessment studies. All these efforts are aimed at the goal of improving the plant staff's ability to cope with unexpected and off-normal events

  12. Unexpected Decrease in Milk Production after Fenbendazole Treatment of Dairy Cows during Early Grazing Season.

    Science.gov (United States)

    Ravinet, Nadine; Chartier, Christophe; Bareille, Nathalie; Lehebel, Anne; Ponnau, Adeline; Brisseau, Nadine; Chauvin, Alain

    2016-01-01

    Gastrointestinal nematodes (GIN) infection can impair milk production (MP) in dairy cows. To investigate whether MP would be optimized by spring targeted-selective anthelmintic treatment in grazing cows, we assessed (1) the effect on MP of an anthelmintic treatment applied 1.5 to 2 months after turn-out, and (2) herd and individual indicators associated with the post-treatment MP response. A randomized controlled clinical trial was conducted in 13 dairy farms (578 cows) in western France in spring 2012. In each herd, lactating cows of the treatment group received fenbendazole orally, control cows remained untreated. Daily cow MP was recorded from 2 weeks before until 15 weeks after treatment. Individual serum pepsinogen and anti-Ostertagia antibody levels (expressed as ODR), faecal egg count and bulk tank milk (BTM) Ostertagia ODR were measured at treatment time. Anthelmintic treatment applied during the previous housing period was recorded for each cow. In each herd, information regarding heifers' grazing and anthelmintic treatment history was collected to assess the Time of Effective Contact (TEC, in months) with GIN infective larvae before the first calving. The effect of treatment on weekly MP averages and its relationships with herd and individual indicators were studied using linear mixed models with two nested random effects (cow within herd). Unexpectedly, spring treatment had a significant detrimental effect on MP (-0.92 kg/cow/day on average). This negative MP response was particularly marked in high producing cows, in cows not treated during the previous housing period or with high pepsinogen levels, and in cows from herds with a high TEC or a high BTM ODR. This post-treatment decrease in MP may be associated with immuno-inflammatory mechanisms. Until further studies can assess whether this unexpected result can be generalized, non-persistent treatment of immunized adult dairy cows against GIN should not be recommended in early grazing season.

  13. Unexpected Decrease in Milk Production after Fenbendazole Treatment of Dairy Cows during Early Grazing Season

    Science.gov (United States)

    Ravinet, Nadine; Chartier, Christophe; Bareille, Nathalie; Lehebel, Anne; Ponnau, Adeline; Brisseau, Nadine; Chauvin, Alain

    2016-01-01

    Gastrointestinal nematodes (GIN) infection can impair milk production (MP) in dairy cows. To investigate whether MP would be optimized by spring targeted-selective anthelmintic treatment in grazing cows, we assessed (1) the effect on MP of an anthelmintic treatment applied 1.5 to 2 months after turn-out, and (2) herd and individual indicators associated with the post-treatment MP response. A randomized controlled clinical trial was conducted in 13 dairy farms (578 cows) in western France in spring 2012. In each herd, lactating cows of the treatment group received fenbendazole orally, control cows remained untreated. Daily cow MP was recorded from 2 weeks before until 15 weeks after treatment. Individual serum pepsinogen and anti-Ostertagia antibody levels (expressed as ODR), faecal egg count and bulk tank milk (BTM) Ostertagia ODR were measured at treatment time. Anthelmintic treatment applied during the previous housing period was recorded for each cow. In each herd, information regarding heifers’ grazing and anthelmintic treatment history was collected to assess the Time of Effective Contact (TEC, in months) with GIN infective larvae before the first calving. The effect of treatment on weekly MP averages and its relationships with herd and individual indicators were studied using linear mixed models with two nested random effects (cow within herd). Unexpectedly, spring treatment had a significant detrimental effect on MP (-0.92 kg/cow/day on average). This negative MP response was particularly marked in high producing cows, in cows not treated during the previous housing period or with high pepsinogen levels, and in cows from herds with a high TEC or a high BTM ODR. This post-treatment decrease in MP may be associated with immuno-inflammatory mechanisms. Until further studies can assess whether this unexpected result can be generalized, non-persistent treatment of immunized adult dairy cows against GIN should not be recommended in early grazing season. PMID

  14. Unexpectedly high burden of rotavirus gastroenteritis in very young infants

    Directory of Open Access Journals (Sweden)

    Reilly Megan

    2010-06-01

    Full Text Available Abstract Background The highest incidence of rotavirus gastroenteritis has generally been reported in children 6-24 months of age. Young infants are thought to be partially protected by maternal antibodies acquired transplacentally or via breast milk. The purpose of our study was to assess the age distribution of children with confirmed community-acquired rotavirus gastroenteritis presenting to an urban referral hospital. Methods Children presenting to The Children's Hospital of Philadelphia with acute gastroenteritis have been monitored for the presence of rotavirus antigen in the stool by ELISA (followed by genotyping if ELISA-positive since the 1994-95 epidemic season. Results Over the last 12 rotavirus seasons prior to the introduction of the pentavalent rotavirus vaccine in 2006, stool specimens from 1646 patients tested positive for community-acquired rotavirus infection. Gender or age was not recorded in 6 and 5 cases, respectively. Overall, 58% of the cases occurred in boys. G1 was the predominant VP7 serotype, accounting for 72% of cases. The median (IQR age was 11 (5-21 months. A total of 790 (48% cases occurred in children outside the commonly quoted peak age range, with 27% in infants 24 months of age. A total of 220 (13% cases occurred during the first 3 months of life, and the highest number of episodes per month of age [97 (6%] was observed during the second month of life. Conclusions The incidence of community-acquired rotavirus gastroenteritis monitored over 12 seasons in the prevaccine era at a major university hospital was nearly constant for each month of age during the first year of life, revealing an unexpectedly high incidence of symptomatic rotavirus disease in infants

  15. Unexpected observations of muons from Cygnus X-3

    International Nuclear Information System (INIS)

    Elbert, J.W.

    1986-01-01

    One surface experiment (Kiel) and two underground experiments (Soudan and Mt. Blanc) have detected unexpectedly large fluxes of cosmic ray muons from the approximate direction of Cygnus X-3, with signals showing the precise period of the system. The muon signals cannot be produced by any known type of elementary particle unless unexpected processes are involved

  16. Amygdala activity can be modulated by unexpected chord functions during music listening.

    Science.gov (United States)

    Koelsch, Stefan; Fritz, Thomas; Schlaug, Gottfried

    2008-12-03

    Numerous earlier studies have investigated the cognitive processing of musical syntax with regular and irregular chord sequences. However, irregular sequences may also be perceived as unexpected, and therefore have a different emotional valence than regular sequences. We provide behavioral data showing that irregular chord functions presented in chord sequence paradigms are perceived as less pleasant than regular sequences. A reanalysis of functional MRI data showed increased blood oxygen level-dependent signal changes bilaterally in the amygdala in response to music-syntactically irregular (compared with regular) chord functions. The combined data indicate that music-syntactically irregular events elicit brain activity related to emotional processes, and that, in addition to intensely pleasurable music or highly unpleasant music, single chord functions can also modulate amygdala activity.

  17. Evaluation of the Factors Concerning the Unexpected Pregnancy of Women who Applied to the Mother and Child Care and Family Planning Center of Van Province

    Directory of Open Access Journals (Sweden)

    Sebahat Gucuk

    2012-02-01

    Full Text Available Introduction: The purpose of this study is to evaluate the experiences of unexpected pregnancy and the related factors of the women who have applied to our center. Material and Method: The study was planned as a descriptive study which enrolled women in the age range of 15-49 on the basis of volunteerism who have applied to the Mother and Child Care and Family Planning Center of Van Province. The participants were administered a survey in which certain situations were questioned, such as age, educational background, age at first labor, income status, number of living children, miscarriage status, unexpected pregnancy status, the presence of trying to undergo an abortion with alternative methods, and the state of receiving consultancy service on pre- and post-pregnancy family planning. Results: The more increased the educational level of 399 women enrolled in the study, the more significant reduction in unexpected pregnancies was detected (P=0.001. When the educational background and the use of alternative methods to have an abortion were compared, the illiterate women were found to use alternative methods (37.6% at a significantly high ratio (p=0.0001. The average of children number of women with at least one unexpected pregnancy was significantly high (p=0.0001. While the ratio of receiving consultancy on post-pregnancy family planning from health care personnel of the women with unexpected pregnancy was 79.5%, a ratio of 97.9% was detected for the women with planned pregnancy which was significantly different (p=0.0001. Conclusion: The health care personnel may reduce the unexpected pregnancies by training women on family planning in a simple, understandable way and by trying to increase health literacy by taking the dominant social rules in our region into consideration. We consider that the primary healthcare will be more effective and result oriented through newly applied Family Practice in our region. Key Words: Unexpected pregnancy

  18. Po-210 high levels in aquatic plants of the Carapebus sandbank, RJ, Brazil

    International Nuclear Information System (INIS)

    Kelecom, Alphonse; Santos, Pedro Lopes dos; Gouvea, Rita de Cassis S.; Dutra, Iedo Ramos; Fevereiro, Paulo Cesar Ayres

    1999-01-01

    210 Po concentration have been determined in one green alga and in five freshwater plants grown in a pond of the Carapebus restinga (state of Rio de Janeiro). The alga Chara sp showed elevated concentration of 210 Po, similar to that observed in marine algae. All the other plants had the lowest concentration of 210 Po in the stems and the highest in the roots. Intermediate values were observed in the leaves. The unexpected high concentration of 210 Po in the roots, even superior to reported values for roots of plants from high radioactive background areas, must be due to the elevated levels of this radionuclide in associated soils that are known to be rich in humic organic material. There seem to have no translocation of this radionuclide from the roots to the other parts of the plants. (author)

  19. Cognitive Readiness: Preparing for the Unexpected

    National Research Council Canada - National Science Library

    Fletcher, J. D

    2004-01-01

    .... Anticipated operational requirements can be decomposed into specific tasks, conditions, and standards, but how should individuals, teams, and units prepare for the unexpected, which, by definition...

  20. Thallium-201 accumulation in cerebral candidiasis: Unexpected finding on SPECT

    International Nuclear Information System (INIS)

    Tonami, N.; Matsuda, H.; Ooba, H.; Yokoyama, K.; Hisada, K.; Ikeda, K.; Yamashita, J.

    1990-01-01

    The authors present an unexpected finding of Tl-201 uptake in the intracerebral lesions due to candidiasis. SPECT demonstrated the extent of the lesions and a high target-to-background ratio. The regions where abnormal Tl-201 accumulation was seen were nearly consistent with CT scans of those enhanced by a contrast agent. After treatment, most of the abnormal Tl-201 accumulation disappeared

  1. Thallium-201 accumulation in cerebral candidiasis: Unexpected finding on SPECT

    Energy Technology Data Exchange (ETDEWEB)

    Tonami, N.; Matsuda, H.; Ooba, H.; Yokoyama, K.; Hisada, K.; Ikeda, K.; Yamashita, J. (Kanazawa Univ. (Japan))

    1990-06-01

    The authors present an unexpected finding of Tl-201 uptake in the intracerebral lesions due to candidiasis. SPECT demonstrated the extent of the lesions and a high target-to-background ratio. The regions where abnormal Tl-201 accumulation was seen were nearly consistent with CT scans of those enhanced by a contrast agent. After treatment, most of the abnormal Tl-201 accumulation disappeared.

  2. 77 FR 21389 - Unexpected Urgent Refugee and Migration Needs

    Science.gov (United States)

    2012-04-10

    ... April 3, 2012 Unexpected Urgent Refugee and Migration Needs Memorandum for the Secretary of State By the... 2(c)(1) of the Migration and Refugee Assistance Act of 1962 (the ``Act''), as amended, (22 U.S.C... United States Emergency Refugee and Migration Assistance Fund, for the purpose of meeting unexpected and...

  3. Pupil dilation during recognition memory: Isolating unexpected recognition from judgment uncertainty.

    Science.gov (United States)

    Mill, Ravi D; O'Connor, Akira R; Dobbins, Ian G

    2016-09-01

    Optimally discriminating familiar from novel stimuli demands a decision-making process informed by prior expectations. Here we demonstrate that pupillary dilation (PD) responses during recognition memory decisions are modulated by expectations, and more specifically, that pupil dilation increases for unexpected compared to expected recognition. Furthermore, multi-level modeling demonstrated that the time course of the dilation during each individual trial contains separable early and late dilation components, with the early amplitude capturing unexpected recognition, and the later trailing slope reflecting general judgment uncertainty or effort. This is the first demonstration that the early dilation response during recognition is dependent upon observer expectations and that separate recognition expectation and judgment uncertainty components are present in the dilation time course of every trial. The findings provide novel insights into adaptive memory-linked orienting mechanisms as well as the general cognitive underpinnings of the pupillary index of autonomic nervous system activity. Copyright © 2016 Elsevier B.V. All rights reserved.

  4. Risk, unexpected uncertainty, and estimation uncertainty: Bayesian learning in unstable settings.

    Directory of Open Access Journals (Sweden)

    Elise Payzan-LeNestour

    Full Text Available Recently, evidence has emerged that humans approach learning using Bayesian updating rather than (model-free reinforcement algorithms in a six-arm restless bandit problem. Here, we investigate what this implies for human appreciation of uncertainty. In our task, a Bayesian learner distinguishes three equally salient levels of uncertainty. First, the Bayesian perceives irreducible uncertainty or risk: even knowing the payoff probabilities of a given arm, the outcome remains uncertain. Second, there is (parameter estimation uncertainty or ambiguity: payoff probabilities are unknown and need to be estimated. Third, the outcome probabilities of the arms change: the sudden jumps are referred to as unexpected uncertainty. We document how the three levels of uncertainty evolved during the course of our experiment and how it affected the learning rate. We then zoom in on estimation uncertainty, which has been suggested to be a driving force in exploration, in spite of evidence of widespread aversion to ambiguity. Our data corroborate the latter. We discuss neural evidence that foreshadowed the ability of humans to distinguish between the three levels of uncertainty. Finally, we investigate the boundaries of human capacity to implement Bayesian learning. We repeat the experiment with different instructions, reflecting varying levels of structural uncertainty. Under this fourth notion of uncertainty, choices were no better explained by Bayesian updating than by (model-free reinforcement learning. Exit questionnaires revealed that participants remained unaware of the presence of unexpected uncertainty and failed to acquire the right model with which to implement Bayesian updating.

  5. Unexpected Decrease in Milk Production after Fenbendazole Treatment of Dairy Cows during Early Grazing Season.

    Directory of Open Access Journals (Sweden)

    Nadine Ravinet

    Full Text Available Gastrointestinal nematodes (GIN infection can impair milk production (MP in dairy cows. To investigate whether MP would be optimized by spring targeted-selective anthelmintic treatment in grazing cows, we assessed (1 the effect on MP of an anthelmintic treatment applied 1.5 to 2 months after turn-out, and (2 herd and individual indicators associated with the post-treatment MP response. A randomized controlled clinical trial was conducted in 13 dairy farms (578 cows in western France in spring 2012. In each herd, lactating cows of the treatment group received fenbendazole orally, control cows remained untreated. Daily cow MP was recorded from 2 weeks before until 15 weeks after treatment. Individual serum pepsinogen and anti-Ostertagia antibody levels (expressed as ODR, faecal egg count and bulk tank milk (BTM Ostertagia ODR were measured at treatment time. Anthelmintic treatment applied during the previous housing period was recorded for each cow. In each herd, information regarding heifers' grazing and anthelmintic treatment history was collected to assess the Time of Effective Contact (TEC, in months with GIN infective larvae before the first calving. The effect of treatment on weekly MP averages and its relationships with herd and individual indicators were studied using linear mixed models with two nested random effects (cow within herd. Unexpectedly, spring treatment had a significant detrimental effect on MP (-0.92 kg/cow/day on average. This negative MP response was particularly marked in high producing cows, in cows not treated during the previous housing period or with high pepsinogen levels, and in cows from herds with a high TEC or a high BTM ODR. This post-treatment decrease in MP may be associated with immuno-inflammatory mechanisms. Until further studies can assess whether this unexpected result can be generalized, non-persistent treatment of immunized adult dairy cows against GIN should not be recommended in early grazing season.

  6. Water in stars: expected and unexpected

    Science.gov (United States)

    Tsuji, T.; Aoki, W.; Ohnaka, K.

    1999-03-01

    We have confirmed the presence of water in the early M giant α Cet (M1.5III) and supergiant KK Per (M2Iab) by the highest resolution grating mode of SWS, but this result is quite unexpected from present model atmospheres. In late M giant and supergiant stars, water observed originates partly in the photosphere as expected by the model atmospheres, but ISO SWS has revealed that the 2.7 mic\\ absorption bands appear to be somewhat stronger than predicted while 6.5 mic\\ bands weaker, indicating the contamination by an emission component. In the mid-infrared region extending to 45 mic, pure rotation lines of hho\\ appear as distinct emission on the high resolution SWS spectra of 30g Her (M7III) and S Per (M4-7Ia), along with the dust emission at 10, 13, 20 mic\\ and a new unidentified feature at 30 mic. Thus, together with the dust, water contributes to the thermal balance of the outer atmosphere already in the mid-infrared. The excitation temperature of hho\\ gas is estimated to be 500 - 1000 K. In view of this result for late M (super)giants, unexpected water observed in early M (super)giants should also be of non-photospheric in origin. Thus, ISO has finally established the presence of a new component of the outer atmosphere - a warm molecular envelope - in red giant and supergiant stars from early to late types. Such a rather warm molecular envelope will be a site of various activities such as chemical reactions, dust formation, mass-outflow etc.

  7. Unexpected High Digestion Rate of Cooked Starch by the Ct-Maltase-Glucoamylase Small Intestine Mucosal α-Glucosidase Subunit

    Science.gov (United States)

    Lin, Amy Hui-Mei; Nichols, Buford L.; Quezada-Calvillo, Roberto; Avery, Stephen E.; Sim, Lyann; Rose, David R.; Naim, Hassan Y.; Hamaker, Bruce R.

    2012-01-01

    For starch digestion to glucose, two luminal α-amylases and four gut mucosal α-glucosidase subunits are employed. The aim of this research was to investigate, for the first time, direct digestion capability of individual mucosal α-glucosidases on cooked (gelatinized) starch. Gelatinized normal maize starch was digested with N- and C-terminal subunits of recombinant mammalian maltase-glucoamylase (MGAM) and sucrase-isomaltase (SI) of varying amounts and digestion periods. Without the aid of α-amylase, Ct-MGAM demonstrated an unexpected rapid and high digestion degree near 80%, while other subunits showed 20 to 30% digestion. These findings suggest that Ct-MGAM assists α-amylase in digesting starch molecules and potentially may compensate for developmental or pathological amylase deficiencies. PMID:22563462

  8. Metatranscriptomic analysis of a high-sulfide aquatic spring reveals insights into sulfur cycling and unexpected aerobic metabolism

    Directory of Open Access Journals (Sweden)

    Anne M. Spain

    2015-09-01

    Full Text Available Zodletone spring is a sulfide-rich spring in southwestern Oklahoma characterized by shallow, microoxic, light-exposed spring water overlaying anoxic sediments. Previously, culture-independent 16S rRNA gene based diversity surveys have revealed that Zodletone spring source sediments harbor a highly diverse microbial community, with multiple lineages putatively involved in various sulfur-cycling processes. Here, we conducted a metatranscriptomic survey of microbial populations in Zodletone spring source sediments to characterize the relative prevalence and importance of putative phototrophic, chemolithotrophic, and heterotrophic microorganisms in the sulfur cycle, the identity of lineages actively involved in various sulfur cycling processes, and the interaction between sulfur cycling and other geochemical processes at the spring source. Sediment samples at the spring’s source were taken at three different times within a 24-h period for geochemical analyses and RNA sequencing. In depth mining of datasets for sulfur cycling transcripts revealed major sulfur cycling pathways and taxa involved, including an unexpected potential role of Actinobacteria in sulfide oxidation and thiosulfate transformation. Surprisingly, transcripts coding for the cyanobacterial Photosystem II D1 protein, methane monooxygenase, and terminal cytochrome oxidases were encountered, indicating that genes for oxygen production and aerobic modes of metabolism are actively being transcribed, despite below-detectable levels (<1 µM of oxygen in source sediment. Results highlight transcripts involved in sulfur, methane, and oxygen cycles, propose that oxygenic photosynthesis could support aerobic methane and sulfide oxidation in anoxic sediments exposed to sunlight, and provide a viewpoint of microbial metabolic lifestyles under conditions similar to those seen during late Archaean and Proterozoic eons.

  9. Unexpected marked seizure improvement in paediatric epilepsy surgery candidates

    DEFF Research Database (Denmark)

    Hoei-Hansen, Christina E; Mathiasen, René; Uldall, Peter

    2017-01-01

    PURPOSE: Epilepsy surgery is performed based on the assumption that medical refractory epilepsy will continue. Rarely seizure freedom occurs before surgery is performed, while the patient is being evaluated as an epilepsy surgery candidate. The aim of this study was to describe the number...... of children withdrawn from an epilepsy surgery programme due to unexpected seizure improvement. METHODS: We retrospectively studied 173 children under 18 years with medical refractory epilepsy referred for epilepsy surgery between 1996 and 2010. Medical records were reviewed in 2012 and 2015. RESULTS......: At the first evaluation point in 2012, 13 patients were withdrawn from the epilepsy surgery programme due to unexpected marked improvement. In 2015, 6 of them were still seizure free. They had unexpected seizure freedom due to change in AED treatment (n=3) or after a febrile episode (n=3). The mean number...

  10. Openness to the unexpected: Our Pathways to Careers in a Federal Research Laboratory.

    Science.gov (United States)

    Newman, Kurt R.; Bunnell, David B.; Hondorp, Darryl W.; Taylor, William W.; Lynch, Abigail J.; Léonard, Nancy J.

    2014-01-01

    Many fisheries professionals may not be in the job they originally envisioned for themselves when they began their undergraduate studies. Rather, their current positions could be the result of unexpected, opportunistic, or perhaps even “lucky” open doors that led them down an unexpected path. In many cases, a mentor helped facilitate the unforeseen trajectory. We offer three unique stories about joining a federal fisheries research laboratory, from the perspective of a scientist, a joint manager-scientist, and a manager. We also use our various experiences to form recommendations that should help the next generation of fisheries professionals succeed in any stop along their journey, including being open to opportunities, setting high expectations, and finding a strong and supportive team environment to work in.

  11. Unexpected Translations in Urban Policy Mobility

    DEFF Research Database (Denmark)

    Zapata, Patrik; Zapata Campos, Maria José

    2015-01-01

    such as prototypes in order to travel. It was made mobile via relational sites or situations providing safe and accessible connections with Chureca residents. Paradoxically, these places also allowed extraordinary connections between actors located in different scales and spaces, facilitating unexpected local...

  12. Unexpected Translations in Urban Policy Mobility

    DEFF Research Database (Denmark)

    Zapata, Patrik; Zapata Campos, Maria José

    such as prototypes in order to travel. It was made mobile via relational sites or situations providing safe and accessible connections with Chureca residents. Paradoxically, these places also allowed extraordinary connections between actors located in different scales and spaces, facilitating unexpected local...

  13. Unexpected Expectations The Curiosities of a Mathematical Crystal Ball

    CERN Document Server

    Wapner, Leonard M

    2012-01-01

    Unexpected Expectations: The Curiosities of a Mathematical Crystal Ball explores how paradoxical challenges involving mathematical expectation often necessitate a reexamination of basic premises. The author takes you through mathematical paradoxes associated with seemingly straightforward applications of mathematical expectation and shows how these unexpected contradictions may push you to reconsider the legitimacy of the applications. The book requires only an understanding of basic algebraic operations and includes supplemental mathematical background in chapter appendices. After a history o

  14. Incidence of sudden unexpected death in epilepsy in community-based cohort in China.

    Science.gov (United States)

    Ge, Yan; Ding, Ding; Zhang, Qing; Yang, Bin; Wang, Taiping; Li, Beixu; Wang, Jie; Luo, Jianfeng; Kwan, Patrick; Wang, Wenzhi; Hong, Zhen; Sander, Josemir W

    2017-11-01

    Sudden unexpected death in epilepsy (SUDEP) is associated with the high premature mortality observed among people with epilepsy. It is, however, considered a rare event in China, probably because of lack of awareness and limitation of studies in the country. We aimed to provide some initial estimation of the burden of SUDEP in China. We established a large Chinese community-based cohort of people with epilepsy between January 2010 and December 2011. For any participant who died during follow-up, detailed information on cause of death was obtained using a specifically designed Verbal Autopsy Questionnaire. All cases were reviewed by a multidisciplinary expert panel and reinvestigated if necessary. Sudden unexpected death in epilepsy incidence rates were estimated and case details provided. The cohort consisted of 1562 people and during a median 5years follow-up, 72 deaths were reported. The all-causes death incidence was 11.23 (95% CI 8.86-14.07) per 1000 person-years. Fifteen died suddenly and unexpectedly in a reasonable state of health in the week preceding death. We recorded detailed information of these 15 deaths. Thirteen were considered to be probable SUDEP and two possible SUDEP. The incidence of probable SUDEP was 2.03 (95% CI 1.13-3.38) per 1000 person-years, and the incidence of all suspected (probable and possible) SUDEP was 2.34 (95% CI 1.36-3.77) per 1000 person-years. The incidence of SUDEP was relatively high among Chinese people with epilepsy when compared with that in previous community-based studies from high-income countries. The burden of SUDEP in China requires further assessments. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. Unexpected findings and promoting monocausal claims, a cautionary tale.

    Science.gov (United States)

    Copeland, Samantha Marie

    2017-10-01

    Stories of serendipitous discoveries in medicine incorrectly imply that the path from an unexpected observation to major discovery is straightforward or guaranteed. In this paper, I examine a case from the field of research about chronic fatigue syndrome (CFS). In Norway, an unexpected positive result during clinical care has led to the development of a research programme into the potential for the immunosuppressant drug rituximab to relieve the symptoms of CFS. The media and public have taken up researchers' speculations that their research results indicate a causal mechanism for CFS - consequently, patients now have great hope that 'the cause' of CFS has been found, and thus, a cure is sure to follow. I argue that a monocausal claim cannot be correctly asserted, either on the basis of the single case of an unexpected, although positive, result or on the basis of the empirical research that has followed up on that result. Further, assertion and promotion of this claim will have specific harmful effects: it threatens to inappropriately narrow the scope of research on CFS, might misdirect research altogether, and could directly and indirectly harm patients. Therefore, the CFS case presents a cautionary tale, illustrating the risks involved in drawing a theoretical hypothesis from an unexpected observation. Further, I draw attention to the tendency in contemporary clinical research with CFS to promote new research directions on the basis of reductive causal models of that syndrome. Particularly, in the case of CFS research, underdetermination and causal complexity undermine the potential value of a monocausal claim. In sum, when an unexpected finding occurs in clinical practice or medical research, the value of following up on that finding is to be found not in the projected value of a singular causal relationship inferred from the finding but rather in the process of research that follows. © 2016 John Wiley & Sons, Ltd.

  16. Unexpectedly large cross sections of high-energy electrons ejected from water vapor by 6.0-10.0 MeV/u He2+ ions

    International Nuclear Information System (INIS)

    Ohsawa, D.; Sato, Y.; Okada, Y.; Shevelko, V.P.; Soga, F.

    2005-01-01

    We present absolute doubly differential cross sections (DDCS) of electron emission (= 2+ ions with water vapor, in which unexpectedly large DDCS values were observed at the backward angles, particularly in the high-energy region, as well as singly differential cross sections larger than the Rudd model by a factor of 2-3 at ∼10 keV. The experimental results imply that these high-energy electrons are accelerated through the Fermi-shuttle acceleration. We evaluated the partial cross sections, which contribute to this acceleration, to be 7.1 and 4.5x10 -19 cm 2 , respectively, leading to ∼0.7% of the total ionization cross sections

  17. Vine vigor, yield and grape quality assessment by airborne remote sensing over three years: Analysis of unexpected relationships in cv. Tempranillo

    Energy Technology Data Exchange (ETDEWEB)

    Bonilla, I.; Martinez de Toda, F.; Martínez-Casasnovas, J.A.

    2015-07-01

    The prediction of grape composition is becoming more important due to the need of reducing the current levels of alcohol and pH of the wines, a problem that is exacerbated by climate change. This work presents a 3-year study of the spatial variability of grape composition in a rainfed Tempranillo vineyard located in Rioja (Spain). It is based on the acquisition of multispectral imagery at véraison (start of the ripening process); and zoning based on NDVI, to assess its performance for zonal management. The results reveal a high spatial variability within the plot, with a stable pattern over the years, even with very different climate conditions. NDVI was a good predictor of vegetative growth variables. However, the prediction of grape composition was more complex. Unexpectedly, anthocyanins were found to be higher in the highest vigor zone, which is probably related to the effects of climate change. This unexpected relationship is particularly discussed in the article. (Author)

  18. Whole Lyophilized Olives as Sources of Unexpectedly High Amounts of Secoiridoids: The Case of Three Tuscan Cultivars.

    Science.gov (United States)

    Cecchi, Lorenzo; Migliorini, Marzia; Cherubini, Chiara; Innocenti, Marzia; Mulinacci, Nadia

    2015-02-04

    The phenolic profiles of three typical Tuscan olive cultivars, Frantoio, Moraiolo, and Leccino, stored in different conditions (fresh, frozen, and whole lyophilized fruits), have been compared during the ripening period. Our main goals were to evaluate the phenolic content of whole freeze-dried fruits and to test the stability of the corresponding cake in oxidative-stress conditions. The comparison of fresh and whole freeze-dried fruits from the 2012 season gave unexpected results; e.g., oleuropein in lyophilized fruits was up to 20 times higher than in fresh olives with values up to 80.3 g/kg. Over time we noted that the olive pastes obtained from lyophilized olives contained highly stable phenolic compounds, even under strong oxidative stress conditions. Finally, it was also observed that the cake/powder obtained from unripe freeze-dried olives was very poor in oil content and therefore quite suitable for use in nutritional supplements rich in phenolic compounds, such as secoiridoids, which are not widely present in the human diet.

  19. The antioxidant level of Alaska's wild berries: high, higher and highest

    Directory of Open Access Journals (Sweden)

    Roxie Rodgers Dinstel

    2013-08-01

    Full Text Available Background . In the last few years, antioxidants have become the stars of the nutritional world. Antioxidants are important in terms of their ability to protect against oxidative cell damage that can lead to conditions, such as Alzheimer's disease, cancer and heart disease – conditions also linked with chronic inflammation. The antioxidant and anti-inflammatory effects of Alaska's wild berries may have the potential to help prevent these diseases. Objective . To discover the antioxidant levels of Alaska wild berries and the ways these antioxidant levels translate when preservation methods are applied to the berry. Design . This research centred on both the raw berries and products made from the berries. In the first year, a variety of wild berries were tested to discover their oxygen radical absorption capacity (ORAC in the raw berries. The second level of the research project processed 4 different berries – blueberries, lingonberries, salmonberries, highbush cranberries – into 8 or 9 products made from these berries. The products were tested for both ORAC as well as specific antioxidants. Results . The Alaska wild berries collected and tested in the first experiment ranged from 3 to 5 times higher in ORAC value than cultivated berries from the lower 48 states. For instance, cultivated blueberries have an ORAC scale of 30. Alaska wild dwarf blueberries measure 85. This is also higher than lower 48 wild blueberries, which had a score of 61. All of the Alaskan berries tested have a level of antioxidant considered nutritionally valuable, ranging from 19 for watermelon berries to 206 for lingonberries on the ORAC scale. With the processed products made from 4 Alaska wild berries, one of the unexpected outcomes of the research was that the berries continued to have levels of antioxidants considered high, despite the effects of commonly used heat-processing techniques. When berries were dehydrated, per gram ORAC values increased. Conclusion

  20. An investigation into the causes of unexpected intra-operative transoesophageal echocardiography findings.

    Science.gov (United States)

    Skinner, H J; Mahmoud, A; Uddin, A; Mathew, T

    2012-04-01

    There is uncertainty regarding echocardiography before cardiac surgery, especially with regard to timing and disease progression as well as potential errors. We investigated the causes of unexpected intra-operative transoesophageal echocardiography findings by performing a 33-month audit. We found that there were 50/797 (6%) unexpected findings that led to an alteration in surgical strategy in 34 (4%) patients. Of the unexpected findings, 25 (50%) were unrelated to pre-operative pathology. After reviewing pre-operative studies and reports, unexpected findings were found to be due to: reporting errors in 20 patients (44%); limitations in transthoracic compared to transoesophageal echocardiography in 14 patients (30%); disease progression in 10 patients (22%); and inter-observer variability in two patients (4%). We identified six reports out of 797 (0.8%) that contained potentially serious errors. Surgical management changed in 18/20 (90%) patients in whom the unexpected change was due to reporting error, compared to 16/30 (53%) patients whose pre-operative echocardiogram was correctly reported (p = 0.006). Our study suggests that pre-operative echocardiography reporting errors are common and important. Anaesthesia © 2012 The Association of Anaesthetists of Great Britain and Ireland.

  1. Unexpected Coexisting Myocardial Infarction Detected by Delayed Enhancement MRI

    Directory of Open Access Journals (Sweden)

    Edouard Gerbaud

    2009-01-01

    Full Text Available We report a case of an unexpected coexisting anterior myocardial infarction detected by delayed enhancement MRI in a 41-year-old man following a presentation with a first episode of chest pain during inferior acute myocardial infarction. This second necrotic area was not initially suspected because there were no ECG changes in the anterior leads and the left descending coronary artery did not present any significant stenoses on emergency coronary angiography. Unrecognised myocardial infarction may carry important prognostic implications. CMR is currently the best imaging technique to detect unexpected infarcts.

  2. Unexpected MRI findings in clinically suspected Legg-Calve-Perthes disease

    Energy Technology Data Exchange (ETDEWEB)

    Lobert, Philip F.; Dillman, Jonathan R.; Strouse, Peter J.; Hernandez, Ramiro J. [University of Michigan Health System, Department of Radiology, Section of Pediatric Radiology, C.S. Mott Children' s Hospital/F3503, Ann Arbor, MI (United States)

    2011-03-15

    In the setting of clinically suspected Legg-Calve-Perthes (LCP) disease and negative/equivocal radiographs, contrast-enhanced MRI can be performed to confirm the diagnosis. To determine the frequency of unexpected causes of hip pain as identified by MRI in children with clinically suspected LCP disease and negative/equivocal radiographs. All pediatric contrast-enhanced MRI examinations of the pelvis and hips performed between January 2000 and February 2009 to evaluate for possible LCP disease in the setting of negative/equivocal radiographs were identified. MRI examinations performed to evaluate for secondary avascular necrosis were excluded. Imaging reports were retrospectively reviewed for unexpected clinically important causes of hip pain. Thirty-six pediatric patients underwent contrast-enhanced MRI examinations for clinically suspected LCP disease in the setting of negative/equivocal radiographs. Twenty-two (61%) imaging studies were normal, while four (11%) imaging studies demonstrated findings consistent with LCP disease. Ten (28%) imaging studies revealed unexpected clinically important causes of hip pain, including nonspecific unilateral joint effusion and synovitis (n = 7, juvenile chronic arthritis was eventually diagnosed in 3 patients), sacral fracture (n = 1), apophyseal injury (n = 1), and femoral head subluxation (n = 1). MRI frequently reveals unexpected clinically important causes of hip pain in children with suspected LCP disease and negative/equivocal radiographs. (orig.)

  3. High-level verification

    CERN Document Server

    Lerner, Sorin; Kundu, Sudipta

    2011-01-01

    Given the growing size and heterogeneity of Systems on Chip (SOC), the design process from initial specification to chip fabrication has become increasingly complex. This growing complexity provides incentive for designers to use high-level languages such as C, SystemC, and SystemVerilog for system-level design. While a major goal of these high-level languages is to enable verification at a higher level of abstraction, allowing early exploration of system-level designs, the focus so far for validation purposes has been on traditional testing techniques such as random testing and scenario-based

  4. Complexity in an Unexpected Place: Quantities in Selected Acquisition Reports

    Science.gov (United States)

    2017-12-01

    by the Army Acquisition Executive contains the following language . As a recently delegated Acquisition Category IC program, the AH-64E Apache...Complexity in an Unexpected Place: Quantities in Selected Acquisition Reports Gregory A. Davis, Project Leader Margaret L. Giles David M. Tate I...F E N S E A N A L Y S E S IDA Paper P-8490 Complexity in an Unexpected Place: Quantities in Selected Acquisition Reports Gregory A. Davis

  5. The intra- and interstate excess market return for low- and high-volatility level

    OpenAIRE

    Poon, Gary

    2006-01-01

    This paper provides a method to estimate the market risk premium that accounts for shifts in investment opportunities by explicitly modeling the volaiility level. This method decomposes the market risk premium into two components., the expected risk premium within the volatility state and risk premium associate with an unexpected change in volatility state. I find that the expected risk premium within the state is negatively related to the market volatility, which is consistent with empirical...

  6. Willingness and ability to pay for unexpected dental expenses by Finnish adults

    Directory of Open Access Journals (Sweden)

    Widström Eeva

    2012-08-01

    Full Text Available Abstract Background Since 2002, adults have been able to choose oral health care services in the public sector or in the private sector in Finland. Though various subsidies for care exist in both sectors, the Public Dental Service (PDS is a cheaper option for the patient but, on the other hand, there are no waiting lists for private care. The aim of this study was to assess middle-aged adults' use of dental services, willingness to pay (WTP and ability to pay (ATP for unexpected, urgent dental treatment. Methods Postal questionnaires on use of dental services were sent to a random sample of 1500 47-59 year old adults living in three large municipalities in the Helsinki region. The initial response rate was 65.8%. Two hypothetical scenarios were presented: "What would be the highest price you would be prepared to pay to have a lost filling replaced immediately, or, at the latest, the day after losing the filling?" and " How much could you pay for unexpected dental expenses at two weeks notice, if you suddenly needed more comprehensive treatment?" Logistic regression analysis was used to analyse factors related to WTP and ATP. Results Most respondents (89.6% had visited a dentist recently and a majority (76.1% had used private services. For immediate replacement of a lost filling, almost all respondents (93.2% were willing to pay the lower price charged in the PDS and 46.2% were willing to pay the private fee. High income and no subjective need for dental treatment were positively associated with the probability of paying a higher price. Most respondents (93.0% were able to pay a low fee, EUR 50 and almost half (41.6% at least EUR 300 for unexpected treatment at short notice. High income and male sex were associated with high ATP. Conclusion There was a strong and statistically significant relationship between income and WTP and ATP for urgent dental care, indicating that access to publicly provided services improved equity for persons with low

  7. Unexpected findings after surgery for suspected appendicitis rarely change treatment in pediatric patients; Results from a cohort study.

    Science.gov (United States)

    Gorter, Ramon R; van Amstel, Paul; van der Lee, Johanna H; van der Voorn, Patick; Bakx, Roel; Heij, Hugo A

    2017-08-01

    To determine if non-operative treatment is safe in children with acute appendicitis, we evaluated the incidence of unexpected findings after an appendectomy in children, and the influence they have on subsequent treatment. A historical cohort study (January 2004-December 2014) was performed including children, aged 0-17 years, who underwent an appendectomy for the suspicion of acute appendicitis. Patients were divided based upon histopathological examination. Unexpected findings were reviewed, as well as the subsequent treatment plan. In total 484 patients were included in this study. In the overall group, unexpected findings were noted in 10 (2.1%) patients of which two patients intra-operatively with a non-inflamed appendix (Ileitis terminalis N=1 and ovarian torsion N=1) and in 8 patients on histopathological examination. The latter group consisted of 4 patients with concomitant simple appendicitis (parasitic infection N=3 and Walthard cell rest N=1), two with concomitant complex appendicitis (carcinoid N=1 and parasitic infection N=1) and two patients with a non-inflamed appendix (endometriosis N=1 and parasitic infection N=1). Treatment was changed in 4 patients (appendicitis, as the occurrence of unexpected findings was low, with extremely few necessary changes of the treatment plan because of serious findings. Prognosis study. Level 2 (retrospective cohort study). Copyright © 2017 Elsevier Inc. All rights reserved.

  8. Unexpected complications of bonded mandibular lingual retainers.

    NARCIS (Netherlands)

    Katsaros, C.; Livas, C.; Renkema, A.M.

    2007-01-01

    INTRODUCTION: The flexible spiral wire (FSW) retainer is the most frequently used type of fixed retainer bonded on all 6 anterior teeth. Our aim in this article was to demonstrate unexpected posttreatment changes in the labiolingual position of the mandibular anterior teeth associated with the use

  9. Unexpected flood loss correlations across Europe

    Science.gov (United States)

    Booth, Naomi; Boyd, Jessica

    2017-04-01

    Floods don't observe country borders, as highlighted by major events across Europe that resulted in heavy economic and insured losses in 1999, 2002, 2009 and 2013. Flood loss correlations between some countries occur along multi-country river systems or between neighbouring nations affected by the same weather systems. However, correlations are not so obvious and whilst flooding in multiple locations across Europe may appear independent, for a re/insurer providing cover across the continent, these unexpected correlations can lead to high loss accumulations. A consistent, continental-scale method that allows quantification and comparison of losses, and identifies correlations in loss between European countries is therefore essential. A probabilistic model for European river flooding was developed that allows estimation of potential losses to pan-European property portfolios. By combining flood hazard and exposure information in a catastrophe modelling platform, we can consider correlations between river basins across Europe rather than being restricted to country boundaries. A key feature of the model is its statistical event set based on extreme value theory. Using historical river flow data, the event set captures spatial and temporal patterns of flooding across Europe and simulates thousands of events representing a full range of possible scenarios. Some known correlations were identified, such as between neighbouring Belgium and Luxembourg where 28% of events that affect either country produce a loss in both. However, our model identified some unexpected correlations including between Austria and Poland, and Poland and France, which are geographically distant. These correlations in flood loss may be missed by traditional methods and are key for re/insurers with risks in multiple countries. The model also identified that 46% of European river flood events affect more than one country. For more extreme events with a return period higher than 200 years, all events

  10. Cannibalistic-morph Tiger Salamanders in unexpected ecological contexts

    Science.gov (United States)

    McLean, Kyle I.; Stockwell, Craig A.; Mushet, David M.

    2016-01-01

    Barred tiger salamanders [Ambystoma mavortium (Baird, 1850)] exhibit two trophic morphologies; a typical and a cannibalistic morph. Cannibalistic morphs, distinguished by enlarged vomerine teeth, wide heads, slender bodies, and cannibalistic tendencies, are often found where conspecifics occur at high density. During 2012 and 2013, 162 North Dakota wetlands and lakes were sampled for salamanders. Fifty-one contained A. mavortium populations; four of these contained cannibalistic morph individuals. Two populations with cannibalistic morphs occurred at sites with high abundances of conspecifics. However, the other two populations occurred at sites with unexpectedly low conspecific but high fathead minnow [Pimephales promelas (Rafinesque, 1820)] abundances. Further, no typical morphs were observed in either of these later two populations, contrasting with earlier research suggesting cannibalistic morphs only occur at low frequencies in salamander populations. Another anomaly of all four populations was the occurrence of cannibalistic morphs in permanent water sites, suggesting their presence was due to factors other than faster growth allowing them to occupy ephemeral habitats. Therefore, our findings suggest environmental factors inducing the cannibalistic morphism may be more complex than previously thought.

  11. 77 FR 42947 - Unexpected Urgent Refugee and Migration Needs

    Science.gov (United States)

    2012-07-20

    ... unexpected and urgent refugee and migration needs, including by contributions to international, governmental, and nongovernmental organizations and payment of administrative expenses of the Bureau of Population...

  12. Frequency, severity and causes of unexpected allergic reactions to food: a systematic literature review.

    Science.gov (United States)

    Versluis, A; Knulst, A C; Kruizinga, A G; Michelsen, A; Houben, G F; Baumert, J L; van Os-Medendorp, H

    2015-02-01

    Food allergic patients have to deal with an avoidance diet. Confusing labelling terms or precautionary labels can result in misinterpretation and risk-taking behaviour. Even those patients that strictly adhere to their diet experience (sometimes severe) unexpected allergic reactions to food. The frequency, severity and causes of such reactions are unknown. The objective of this review was to describe the frequency, severity and causes of unexpected allergic reactions to food in food allergic patients aged > 12 years, in order to develop improved strategies to deal with their allergy. A systematic review was carried out by two researchers, in six electronic databases (CINAHL, Cochrane, EMBASE, Medline, Psychinfo and Scopus). The search was performed with keywords relating to the frequency, severity and causes of unexpected allergic reactions to food. This resulted in 24 studies which met the inclusion criteria; 18 observational and six qualitative studies. This review shows that knowledge about the frequency of unexpected reactions is limited. Peanut, nuts, egg, fruit/vegetables and milk are the main causal foods. Severe reactions and even fatalities occur. Most reactions take place at home, but a significant number also take place when eating at friends' houses or in restaurants. Labelling issues, but also attitude and risky behaviour of patients can attribute to unexpected reactions. We conclude that prospective studies are needed to get more insight in the frequency, severity, quantity of unintended allergen ingested and causes of unexpected allergic reactions to food, to be able to optimize strategies to support patients in dealing with their food allergy. Although the exact frequency is not known, unexpected reactions to food occur in a significant number of patients and can be severe. For clinical practice, this means that patient education and dietary instructions are necessary. © 2014 John Wiley & Sons Ltd.

  13. Unexpected secoiridoid glucosides from Manulea corymbosa.

    Science.gov (United States)

    Gousiadou, Chrysoula; Kokubun, Tetsuo; Gotfredsen, Charlotte H; Jensen, Søren R

    2014-03-28

    From an extract of Manulea corymbosa were isolated four known secoiridoid glucosides (1-4), 10 new monoterpenoid esters of secologanol, namely, manuleosides A-I (5-11, 13, and 14) and dimethyl rhodanthoside A (12), and four new phenylpropanoid esters of carbocyclic iridoid glucosides, manucorymbosides I-IV (15-18). Also, the caffeoyl phenylethanoid glycoside verbascoside was isolated. The presence of secoiridoids apparently derived from loganic acid in the family Scrophulariaceae is unprecedented and greatly unexpected.

  14. Sudden Unexpected Death During Sleep in Familial Dysautonomia: A Case-Control Study.

    Science.gov (United States)

    Palma, Jose-Alberto; Norcliffe-Kaufmann, Lucy; Perez, Miguel A; Spalink, Christy L; Kaufmann, Horacio

    2017-08-01

    Sudden unexpected death during sleep (SUDS) is the most common cause of death in patients with familial dysautonomia (FD), an autosomal recessive disease characterized by sensory and autonomic dysfunction. It remains unknown what causes SUDS in these patients and who is at highest risk. We tested the hypothesis that SUDS in FD is linked to sleep-disordered breathing. We retrospectively identified patients with FD who died suddenly and unexpectedly during sleep and had undergone polysomnography within the 18-month period before death. For each case, we sampled one age-matched surviving subject with FD that had also undergone polysomnography within the 18-month period before study. Data on polysomnography, EKG, ambulatory blood pressure monitoring, arterial blood gases, blood count, and metabolic panel were analyzed. Thirty-two deceased cases and 31 surviving controls were included. Autopsy was available in six cases. Compared with controls, participants with SUDS were more likely to be receiving treatment with fludrocortisone (odds ratio [OR]; 95% confidence interval) (OR 29.7; 4.1-213.4), have untreated obstructive sleep apnea (OR 17.4; 1.5-193), and plasma potassium levels Sleep Research Society 2017. Published by Oxford University Press on behalf of the Sleep Research Society. All rights reserved. For permissions, please e-mail journals.permissions@oup.com.

  15. Unexpected Secoiridoid Glucosides from Manulea corymbosa

    DEFF Research Database (Denmark)

    Gousiadou, Chrysoula; Kokubun, Tetsuo; Gotfredsen, Charlotte Held

    2014-01-01

    From an extract of Manulea corymbosa were isolated four known secoiridoid glucosides (1–4), 10 new monoterpenoid esters of secologanol, namely, manuleosides A–I (5–11, 13, and 14) and dimethyl rhodanthoside A (12), and four new phenylpropanoid esters of carbocyclic iridoid glucosides, manucorymbo......, manucorymbosides I–IV (15–18). Also, the caffeoyl phenylethanoid glycoside verbascoside was isolated. The presence of secoiridoids apparently derived from loganic acid in the family Scrophulariaceae is unprecedented and greatly unexpected....

  16. Subclinical hyperthyroidism and sudden unexpected death in epilepsy.

    Science.gov (United States)

    Scorza, Fulvio A; Arida, Ricardo M; Cysneiros, Roberta M; Terra, Vera C; de Albuquerque, Marly; Machado, Hélio R; Cavalheiro, Esper A

    2010-04-01

    Epilepsy is the most common serious neurological condition and sudden unexpected death in epilepsy (SUDEP) is the most important direct epilepsy-related cause of death. Information concerning risk factors for SUDEP is conflicting, but high seizure frequency is a potential risk factor. Additionally, potential pathomechanisms for SUDEP are unknown, but it is very probable that cardiac arrhythmias during and between seizures or transmission of epileptic activity to the heart via the autonomic nervous system potentially play a role. In parallel, several studies have shown a link between hormones and epilepsy. However, exact knowledge regarding the association of thyroid hormones and epilepsy is lacking. As subclinical hyperthyroidism has been linked with increased risk of cardiovascular disease, we propose in this paper that SUDEP, at least in some cases, could be related with subclinical thyroid dysfunction. (c) 2009 Elsevier Ltd. All rights reserved.

  17. Unexpected consequences of control: competitive vs. predator release in a four-species assemblage of invasive mammals.

    Science.gov (United States)

    Ruscoe, Wendy A; Ramsey, David S L; Pech, Roger P; Sweetapple, Peter J; Yockney, Ivor; Barron, Mandy C; Perry, Mike; Nugent, Graham; Carran, Roger; Warne, Rodney; Brausch, Chris; Duncan, Richard P

    2011-10-01

    Invasive species are frequently the target of eradication or control programmes to mitigate their impacts. However, manipulating single species in isolation can lead to unexpected consequences for other species, with outcomes such as mesopredator release demonstrated both theoretically and empirically in vertebrate assemblages with at least two trophic levels. Less is known about the consequences of species removal in more complex assemblages where a greater number of interacting invaders increases the potential for selective species removal to result in unexpected changes in community structure. Using a replicated Before-After Control-Impact field experiment with a four-species assemblage of invasive mammals we show that species interactions in the community are dominated by competition rather than predation. There was no measurable response of two mesopredators (rats and mice) following control of the top predator (stoats), but there was competitive release of rats following removal of a herbivore (possums), and competitive release of mice following removal of rats. © 2011 Blackwell Publishing Ltd/CNRS.

  18. High-level language computer architecture

    CERN Document Server

    Chu, Yaohan

    1975-01-01

    High-Level Language Computer Architecture offers a tutorial on high-level language computer architecture, including von Neumann architecture and syntax-oriented architecture as well as direct and indirect execution architecture. Design concepts of Japanese-language data processing systems are discussed, along with the architecture of stack machines and the SYMBOL computer system. The conceptual design of a direct high-level language processor is also described.Comprised of seven chapters, this book first presents a classification of high-level language computer architecture according to the pr

  19. Other-than-high-level waste

    International Nuclear Information System (INIS)

    Bray, G.R.

    1976-01-01

    The main emphasis of the work in the area of partitioning transuranic elements from waste has been in the area of high-level liquid waste. But there are ''other-than-high-level wastes'' generated by the back end of the nuclear fuel cycle that are both large in volume and contaminated with significant quantities of transuranic elements. The combined volume of these other wastes is approximately 50 times that of the solidified high-level waste. These other wastes also contain up to 75% of the transuranic elements associated with waste generated by the back end of the fuel cycle. Therefore, any detailed evaluation of partitioning as a viable waste management option must address both high-level wastes and ''other-than-high-level wastes.''

  20. Increasing the Stimulation Dose of rFSH in Unexpected Poor Responders Is Not Associated with Better IVF Outcome

    Directory of Open Access Journals (Sweden)

    Levent Tutuncu

    2012-01-01

    Full Text Available The aim of this retrospective study is to determine whether increasing the stimulation dose of rFSH in unexpected poor responders is associated with better in vitro fertilization (IVF outcome or not. A total of forty eligible women who fulfilled our definition of poor responders and who did not achieve an ongoing pregnancy in the first cycle and returned for a second higher rFSH dose IVF cycle with a long-agonist protocol were included to the study. The first low-dose cycles and the second high-dose cycles were compared to each other. Main outcome measures of the study were duration of stimulation, number of follicles, number of oocytes retrieved, number of embryos, and E2 level on day of hCG injection. There were no significant differences in duration of stimulation, number of follicles, number of oocytes retrieved, number of embryos, and E2 level on day of hCG injection between the first low- and second high-dose cycles. Daily dose and total dose of rFSH were significantly higher in the second high-dose cycles. Increasing the dose of rFSH in a second stimulation cycle after first unsuccessful treatment cycle will add only to the cost and discomfort of the treatment and might adversely affect pregnancy rates.

  1. Lifting an unexpectedly heavy object : the effects on low-back loading and balance loss

    NARCIS (Netherlands)

    van der Burg, J C; van Dieën, J H; Toussaint, H M

    OBJECTIVE: This study evaluates the effects of lifting an unexpectedly heavy object on low-back loading and loss of balance. BACKGROUND: It is often suggested that lifting an unexpectedly heavy object may be a major risk factor for low-back pain. This may lead to an increase in muscle activation,

  2. Working memory representations persist in the face of unexpected task alterations.

    Science.gov (United States)

    Swan, Garrett; Wyble, Brad; Chen, Hui

    2017-07-01

    It is well known that information can be held in memory while performing other tasks concurrently, such as remembering a color or number during a separate visual search task. However, it is not clear what happens to stored information in the face of unexpected tasks, such as the surprise questions that are often used in experiments related to inattentional and change blindness. Does the unpredicted shift in task context cause memory representations to be cleared in anticipation of new information? To answer this question, we ran two experiments where the task unexpectedly switched partway through the experiment with a surprise question. Half of the participants were asked to report the same attribute (Exp. 1 = Identity, Exp. 2 = Color) of a target stimulus in both presurprise and postsurprise trials, while for the other half, the reported attribute switched from identity to color (Exp. 1) or vice versa (Exp. 2). Importantly, all participants had to read an unexpected set of instructions and respond differently on the surprise trial. Accuracy on the surprise trial was higher for the same-attribute groups than the different-attribute groups. Furthermore, there was no difference in reaction time on the surprise trial between the two groups. These results suggest that information participants expected to report can survive an encounter with an unexpected task. The implication is that failures to report information on a surprise trial in many experiments reflect genuine differences in memory encoding, rather than forgetting or overwriting induced by the surprise question.

  3. Investigating Initial Disclosures and Reactions to Unexpected, Positive HPV Diagnosis.

    Science.gov (United States)

    Smith, Rachel A; Hernandez, Rachael; Catona, Danielle

    2014-07-01

    Initial disclosures of health conditions are critical communication moments. Existing research focuses on disclosers; integrating confidants into studies of initial disclosures is needed. Guided by the disclosure decision-making model (DD-MM; Greene, 2009), this study examined what diagnosed persons and confidants may say when faced with unexpected test results and unexpected disclosures, respectively. Participants ( N = 151) recorded an audio-visual message for another person, after imagining that they or the other person had just received unexpected, positive HPV test results. The qualitative analysis revealed four themes: (1) impression management and social distance, (2) invisible symptoms and advice regarding future disclosures, (3) expressing and acknowledging emotional reactions, and (4) misunderstandings and lacking knowledge about HPV. These findings suggested that DD-MM may be a relevant framework for understanding not only when disclosers share, but what disclosers and confidants say in early conversations about new diagnoses. While disclosers' and confidants' messages showed marked similarities, important differences appeared. For example, confidants focused on assuaging disclosers' fear about the consequences, whereas disclosers expressed distress related to their uncertainty about the prognosis of an HPV infection and how to prepare for next steps. The discussion highlighted implications for the DD-MM, HPV disclosures, and future interventions.

  4. Mathematics Placement Test: Typical Results with Unexpected Outcomes

    Science.gov (United States)

    Ingalls, Victoria

    2011-01-01

    Based on the results of a prior case-study analysis of mathematics placement at one university, the mathematics department developed and piloted a mathematics placement test. This article describes the implementation process for a mathematics placement test and further analyzes the test results for the pilot group. As an unexpected result, the…

  5. The management of high-level radioactive wastes

    International Nuclear Information System (INIS)

    Lennemann, Wm.L.

    1979-01-01

    The definition of high-level radioactive wastes is given. The following aspects of high-level radioactive wastes' management are discussed: fuel reprocessing and high-level waste; storage of high-level liquid waste; solidification of high-level waste; interim storage of solidified high-level waste; disposal of high-level waste; disposal of irradiated fuel elements as a waste

  6. The processing of unexpected positive response outcomes in the mediofrontal cortex.

    Science.gov (United States)

    Ferdinand, Nicola K; Mecklinger, Axel; Kray, Jutta; Gehring, William J

    2012-08-29

    The human mediofrontal cortex, especially the anterior cingulate cortex, is commonly assumed to contribute to higher cognitive functions like performance monitoring. How exactly this is achieved is currently the subject of lively debate but there is evidence that an event's valence and its expectancy play important roles. One prominent theory, the reinforcement learning theory by Holroyd and colleagues (2002, 2008), assigns a special role to feedback valence, while the prediction of response-outcome (PRO) model by Alexander and Brown (2010, 2011) claims that the mediofrontal cortex is sensitive to unexpected events regardless of their valence. However, paradigms examining this issue have included confounds that fail to separate valence and expectancy. In the present study, we tested the two competing theories of performance monitoring by using an experimental task that separates valence and unexpectedness of performance feedback. The feedback-related negativity of the event-related potential, which is commonly assumed to be a reflection of mediofrontal cortex activity, was elicited not only by unexpected negative feedback, but also by unexpected positive feedback. This implies that the mediofrontal cortex is sensitive to the unexpectedness of events in general rather than their valence and by this supports the PRO model.

  7. Unexpected pathological findings in skills training and assessing skills

    NARCIS (Netherlands)

    Boendermaker, PM; Pols, J; Scherpbier, AJJA

    This article draws attention to unexpected pathological findings encountered by students and teachers when examining one another and/or simulated patients in skips training and assessment sessions. Although no literature on the subject was found it appears to be not uncommon far students and

  8. Unexpected strong attraction in the presence of continuum bound state

    International Nuclear Information System (INIS)

    Delfino, A.; Frederico, T.

    1992-06-01

    The result of few-particle ground-state calculation employing a two-particle non-local potential supporting a continuum bound state in addition to a negative-energy bound state has occasionally revealed unexpected large attraction in producing a very strongly bound ground state. In the presence of the continuum bound state the difference of phase shift between zero and infinite energies has an extra jump of φ as in the presence of an additional bound state. The wave function of the continuum bound state is identical with that of a strongly bound negative-energy state, which leads us to postulate a pseudo bound state in the two-particle system in order to explain the unexpected attraction. The role of the Pauli forbidden states is expected to be similar to these pseudo states. (author)

  9. An Unexpected Case of Lyme Disease in a Soldier Serving in Northern Iraq

    Science.gov (United States)

    2010-05-01

    MILITARY MEDICINE, 175,5:367,2010 An Unexpected Case of Lyme Disease in a Soldier Serving in Northern Iraq CPT Jeremy B. Fisher, SP USA *; CPT...Christopher E. Curtis, MC USAt 188143 ABSTRACT Lyme disease is a tick-transmitted disease caused by the spirochete Borrelia burgdorferi. Cases have been...Turkey.3-S We report an unexpected case of Lyme disease from Iraq. CASE REPORT A 28-year-old active duty Army male, on a deployment to northern Iraq

  10. The Investigation of Unexpected Arsenic Compounds Observed in Routine Biological Monitoring Urinary Speciation Analysis

    Directory of Open Access Journals (Sweden)

    Elizabeth Leese

    2017-05-01

    Full Text Available This study investigates the identity of two unexpected arsenic species found separately in a number of urine samples sent to the Health and Safety Executive’s Health and Safety Laboratory for arsenic speciation (arsenobetaine, AB; arsenite, As3+; arsenate, As5+; monomethylarsonic acid, MMA5+; and dimethylarsinic acid, DMA5+. Micro liquid chromatography coupled to inductively coupled plasma mass spectrometry (µLC-ICP-MS and electrospray time of flight tandem mass spectrometry (ESI-QqTOF-MS/MS were used to identify the two arsenic peaks by comparison to several characterized arsenicals: arsenocholine, AC; trimethyl arsine oxide, TMAO; dimethylarsenoacetate, DMAA; dimethylarsenoethanol, DMAE; thio-dimethylarsinate, thio-DMA; thio-dimethylarsenoacetate, thio-DMAA and thio-dimethylarsenoethanol, thio-DMAE. The results from both the ICP-MS and ESI-QqTOF-MS/MS investigations indicate that the unexpected arsenic species termed peak 1 was thio-DMA. While the unexpected arsenic species termed peak 2 has yet to be identified, this investigation shows that it was not AC, TMAO, DMAA, DMAE, thio-DMA, thio-DMAA or thio-DMAE. This study demonstrates the incidence of unexpected arsenic species in both routine and non-routine urine samples from both workers and hospital patients.

  11. Process improvement methodologies uncover unexpected gaps in stroke care.

    Science.gov (United States)

    Kuner, Anthony D; Schemmel, Andrew J; Pooler, B Dustin; Yu, John-Paul J

    2018-01-01

    Background The diagnosis and treatment of acute stroke requires timed and coordinated effort across multiple clinical teams. Purpose To analyze the frequency and temporal distribution of emergent stroke evaluations (ESEs) to identify potential contributory workflow factors that may delay the initiation and subsequent evaluation of emergency department stroke patients. Material and Methods A total of 719 sentinel ESEs with concurrent neuroimaging were identified over a 22-month retrospective time period. Frequency data were tabulated and odds ratios calculated. Results Of all ESEs, 5% occur between 01:00 and 07:00. ESEs were most frequent during the late morning and early afternoon hours (10:00-14:00). Unexpectedly, there was a statistically significant decline in the frequency of ESEs that occur at the 14:00 time point. Conclusion Temporal analysis of ESEs in the emergency department allowed us to identify an unexpected decrease in ESEs and through process improvement methodologies (Lean and Six Sigma) and identify potential workflow elements contributing to this observation.

  12. RPython high-level synthesis

    Science.gov (United States)

    Cieszewski, Radoslaw; Linczuk, Maciej

    2016-09-01

    The development of FPGA technology and the increasing complexity of applications in recent decades have forced compilers to move to higher abstraction levels. Compilers interprets an algorithmic description of a desired behavior written in High-Level Languages (HLLs) and translate it to Hardware Description Languages (HDLs). This paper presents a RPython based High-Level synthesis (HLS) compiler. The compiler get the configuration parameters and map RPython program to VHDL. Then, VHDL code can be used to program FPGA chips. In comparison of other technologies usage, FPGAs have the potential to achieve far greater performance than software as a result of omitting the fetch-decode-execute operations of General Purpose Processors (GPUs), and introduce more parallel computation. This can be exploited by utilizing many resources at the same time. Creating parallel algorithms computed with FPGAs in pure HDL is difficult and time consuming. Implementation time can be greatly reduced with High-Level Synthesis compiler. This article describes design methodologies and tools, implementation and first results of created VHDL backend for RPython compiler.

  13. Dealing with unexpected events : efficient and safe solutions to emergent repair on NPP

    Energy Technology Data Exchange (ETDEWEB)

    Liekens Massazza, I.

    2015-07-01

    Nuclear Facilities are constantly challenged with unexpected events occurring on Primary Circuit components. A solution must be deployed quickly to minimize impact on the scheduled outage duration while guaranteeing safety, quality and ALARA standards. AREVA NP has demonstrated worldwide recognized capabilities and expertise through efficient management of various unexpected forced events through the time. Turnkey packaged solutions which are proposed are based on proven technics which can be quickly adapted and qualified to the specific problem, resulting in customers’ full satisfaction. (Author)

  14. Gastric Adenomyoma: The Unexpected Mimicker

    Directory of Open Access Journals (Sweden)

    Marcela Adriana Duran Álvarez

    2017-01-01

    Full Text Available Gastric adenomyoma is a rare benign tumor composed of epithelial structures and smooth muscle stroma. Here, we report an unusual case of gastric adenomyoma mostly composed of smooth muscle that was incidentally found during a laparoscopic intervention. On radiology, it mimicked an acquired hypertrophic pyloric stenosis in an adult patient, and pathologically it resembled a pure smooth muscle hamartoma. Complete submission of the lesion for histology was necessary to find the epithelial component and make the right diagnosis. As a mimicker of benign and malignant entities, gastric adenomyoma is usually an unexpected finding after surgery. The aim of this report is to analyze this adenomyoma variant in the setting of an unexplained thickening of the gastric wall, with explanations concerning histogenesis and biological potential.

  15. Communication of Unexpected and Significant Findings on Chest Radiographs With an Automated PACS Alert System.

    LENUS (Irish Health Repository)

    Hayes, Sara A

    2014-08-01

    An integral part of realizing the enormous potential of imaging in patient care is close communication between radiologists and referring physicians. One key element of this process is the communication of unexpected significant findings. The authors examined the performance of a PACS-based alert system in the appropriate communication of reports containing unexpected significant findings to referring physicians.

  16. High potassium level

    Science.gov (United States)

    ... level is very high, or if you have danger signs, such as changes in an ECG . Emergency ... Seifter JL. Potassium disorders. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine . 25th ed. Philadelphia, PA: ...

  17. High-level Petri Nets

    DEFF Research Database (Denmark)

    various journals and collections. As a result, much of this knowledge is not readily available to people who may be interested in using high-level nets. Within the Petri net community this problem has been discussed many times, and as an outcome this book has been compiled. The book contains reprints...... of some of the most important papers on the application and theory of high-level Petri nets. In this way it makes the relevant literature more available. It is our hope that the book will be a useful source of information and that, e.g., it can be used in the organization of Petri net courses. To make......High-level Petri nets are now widely used in both theoretical analysis and practical modelling of concurrent systems. The main reason for the success of this class of net models is that they make it possible to obtain much more succinct and manageable descriptions than can be obtained by means...

  18. Many unexpected abdominal findings on staging computed tomography in patients with colorectal cancer

    DEFF Research Database (Denmark)

    Holmsted, Kim; Nørring, Keld; Laustrup, Lene Collatz

    2011-01-01

    ; an issue that was previously studied in relation to CT colonography, but not in relation to staging CT with intravenous contrast in CRC patients. The aim of the present study was to evaluate the number and significance of such unexpected findings on staging CTs in CRC patients.......Computed tomography (CT) was proven to be superior to preoperative abdominal ultrasound in the preoperative setting for detection of hepatic metastases from colorectal cancer (CRC). The higher sensitivity of CT has resulted in a number of unexpected abdominal findings of varying importance...

  19. Unexpected weak seasonal climate in the western Mediterranean region during MIS 31, a high-insolation forced interglacial

    Science.gov (United States)

    Oliveira, Dulce; Sánchez Goñi, Maria Fernanda; Naughton, Filipa; Polanco-Martínez, J. M.; Jimenez-Espejo, Francisco J.; Grimalt, Joan O.; Martrat, Belen; Voelker, Antje H. L.; Trigo, Ricardo; Hodell, David; Abrantes, Fátima; Desprat, Stéphanie

    2017-04-01

    Marine Isotope Stage 31 (MIS 31) is an important analogue for ongoing and projected global warming, yet key questions remain about the regional signature of its extreme orbital forcing and intra-interglacial variability. Based on a new direct land-sea comparison in SW Iberian margin IODP Site U1385 we examine the climatic variability between 1100 and 1050 ka including the ;super interglacial; MIS 31, a period dominated by the 41-ky obliquity periodicity. Pollen and biomarker analyses at centennial-scale-resolution provide new insights into the regional vegetation, precipitation regime and atmospheric and oceanic temperature variability on orbital and suborbital timescales. Our study reveals that atmospheric and SST warmth during MIS 31 was not exceptional in this region highly sensitive to precession. Unexpectedly, this warm stage stands out as a prolonged interval of a temperate and humid climate regime with reduced seasonality, despite the high insolation (precession minima values) forcing. We find that the dominant forcing on the long-term temperate forest development was obliquity, which may have induced a decrease in summer dryness and associated reduction in seasonal precipitation contrast. Moreover, this study provides the first evidence for persistent atmospheric millennial-scale variability during this interval with multiple forest decline events reflecting repeated cooling and drying episodes in SW Iberia. Our direct land-sea comparison shows that the expression of the suborbital cooling events on SW Iberian ecosystems is modulated by the predominance of high or low-latitude forcing depending on the glacial/interglacial baseline climate states. Severe dryness and air-sea cooling is detected under the larger ice volume during glacial MIS 32 and MIS 30. The extreme episodes, which in their climatic imprint are similar to the Heinrich events, are likely related to northern latitude ice-sheet instability and a disruption of the Atlantic Meridional Overturning

  20. Unexpected sneezing after a peribulbar injection in a patient for ...

    African Journals Online (AJOL)

    ... anaesthetic in awake patients. We present a case report of an awake elderly male who experienced unexpected continuous sneezing immediately after the removal of the needle used for the peribulbar block, which was subsequently relieved with pheniramine maleate. Keywords: peribulbar block, pheniramine maleate, ...

  1. The vital few meet the trivial many: unexpected use patterns in a monographs collection.

    Science.gov (United States)

    Eldredge, J D

    1998-01-01

    PURPOSE: To test three related hypotheses about monographs circulation at academic health sciences libraries: (1) Juran's "Vital Few" Principle, sometimes incorrectly referred to as the "Pareto Principle"; (2) most (> 30%) new monographs will not circulate within four years; and, (3) Trueswell's 20/80 rule concerning intensity of monographs circulation. METHODS: Retrospective circulation study conducted at a major academic health sciences library in November 1997 on monographs acquired during 1993, utilizing an online review file. RESULTS: Unexpectedly, most monographs (84%) had circulated at least once in the four years following acquisition. Combining circulation and in-house data revealed that 90.7% of the monographs acquired in 1993 had been used at least once. Small percentages of these monographs produced disproportionately high circulation levels. CONCLUSION: Monographs circulation rates confirm Juran's Vital Few principle. Most monographs circulated at least once in contrast to results reported by the Pittsburgh Study or other studies reported by Hardesty and Fenske. The results do not comply with Trueswell's 20/80 ratio rule. Further research needs to investigate the effects of low students to books ratios and problem-based learning (PBL) curricula upon monographs utilization. PMID:9803291

  2. The cheater's high: the unexpected affective benefits of unethical behavior.

    Science.gov (United States)

    Ruedy, Nicole E; Moore, Celia; Gino, Francesca; Schweitzer, Maurice E

    2013-10-01

    Many theories of moral behavior assume that unethical behavior triggers negative affect. In this article, we challenge this assumption and demonstrate that unethical behavior can trigger positive affect, which we term a "cheater's high." Across 6 studies, we find that even though individuals predict they will feel guilty and have increased levels of negative affect after engaging in unethical behavior (Studies 1a and 1b), individuals who cheat on different problem-solving tasks consistently experience more positive affect than those who do not (Studies 2-5). We find that this heightened positive affect does not depend on self-selection (Studies 3 and 4), and it is not due to the accrual of undeserved financial rewards (Study 4). Cheating is associated with feelings of self-satisfaction, and the boost in positive affect from cheating persists even when prospects for self-deception about unethical behavior are reduced (Study 5). Our results have important implications for models of ethical decision making, moral behavior, and self-regulatory theory.

  3. Peculiar time dependence of unexpected lines in delayed beam-foil X-ray spectra of V, Fe and Ni

    International Nuclear Information System (INIS)

    Ahmad, Nissar; Karn, Ranjeet K.; Marketos, Pan; Nandi, T.

    2005-01-01

    Delayed beam-foil X-ray spectra of highly charged ions of V, Fe and Ni show a few lines at energies higher than the H-like Lyman α-line of the respective projectile ions. These can only be attributed to heavier ions. Further the time dependence of such unexpected lines display a peculiar behavior. This work presents the experimental observations systematically

  4. When an Object Appears Unexpectedly: Object Circumvention in Adults.

    Science.gov (United States)

    Wilmut, Kate; Du, Wenchong; Barnett, Anna L

    2017-01-01

    Obstacles often appear unexpectedly in our pathway and these require us to make immediate adjustments. Despite how regularly we encounter such situations only few studies have considered how we adjust to unexpected obstacles in the pathway that require us to walk around them. The authors considered how adults adjust to the possibility of an obstacle appearing and then also how foot placement is adjusted to circumvent an obstacle. Fifteen healthy adults walked down an 11-m walkway, initially they were told this was a clear pathway and nothing in the environment would change (no gate), they then performed a series of trials in which a gate may (gate close) or may not (gate open) partially obstruct their pathway. The authors found that mediolateral trunk velocity and acceleration was significantly increased when there was the possibility of an obstacle but before the obstacle appeared. This demonstrates an adaptive walking strategy that seems to enable healthy young adults to successfully circumvent obstacles. The authors also categorized foot placement adjustments and found that adults favored making shorter and wider steps away from the obstacle. They suggest this combination of adjustments allows participants to maintain stability while successfully circumventing the obstacle.

  5. High-Sensitive C-Reactive Protein Levels in a Group of Syrian University Male Students and Its Associations with Smoking, Physical Activity, Anthropometric Measurements, and Some Hematologic Inflammation Biomarkers

    Directory of Open Access Journals (Sweden)

    Wafika Zarzour

    2017-01-01

    Full Text Available In Syria, health risk data on young males are limited. Hence, the aim of the present study was to evaluate cardiovascular disease (CVD risk factors along with C-reactive protein levels measured by high-sensitive method (hsCRP in a group of healthy males of university students (n=101, 18–25 years old. Participants’ anthropometric characteristics; alcohol drinking, smoking, and physical activity habits; parents medical history; and some inflammatory biomarkers were inspected for their associations with hsCRP. Results. Regarding hsCRP level, 19 participants were at average (1–3 mg/L and 13 were at high (>3 mg/L risk of CVD. Nonparametric statistical tests (p value < 0.05 revealed that hsCRP level was higher in participants who had high body mass index (BMI, had high BMI with high waist-to-hip ratio (WHR, or did not practice sport frequently. Unexpectedly, it did not vary between smokers and nonsmokers. In general, it correlated positively with anthropometric and erythrocyte sedimentation rate (ESR measurements. Nevertheless, it negatively correlated with sports practicing in overall and nonsmoker groups and in participants whose parents were without medical history. Finally, when participants with high BMI were smokers, did not practice sport frequently, or had a parent with medical history, their hsCRP levels were higher than others who had the same circumstances but with low BMI.

  6. Frequentie en oorzaak van onverwachte allergische reacties op voedsel [Frequency and cause of unexpected allergic reactions to food

    NARCIS (Netherlands)

    Michelsen-Huisman, A.D.; Os-Medendorp, H. van; Versluis, A.; Kruizinga, A.G.; Castenmiller, J.J.M.; Noteborn, H.P.J.M.; Houben, G.F.; Knulst, A.C.

    2014-01-01

    Unexpected reactions occur in patients with food allergy, but frequency data are scare. This prospective study investigates the frequency, severity and causes of unexpected allergic reactions to food in adults with a doctor's diagnosed food allergy. Participants complete an online questionnaire

  7. Responding In-the-Moment: Learning to Prepare for the Unexpected

    Science.gov (United States)

    Mason, John

    2015-01-01

    Becoming aware of something unexpected can be a form of awakening: sharpening attention, enriching noticing, opening up fresh possibilities of action, and educating awareness so as to enable a sensitive response to similar situations in the future. However it can also trigger tunnel vision (few if any actions available) or freezing (no actions…

  8. EAP high-level product architecture

    DEFF Research Database (Denmark)

    Guðlaugsson, Tómas Vignir; Mortensen, Niels Henrik; Sarban, Rahimullah

    2013-01-01

    EAP technology has the potential to be used in a wide range of applications. This poses the challenge to the EAP component manufacturers to develop components for a wide variety of products. Danfoss Polypower A/S is developing an EAP technology platform, which can form the basis for a variety...... of EAP technology products while keeping complexity under control. High level product architecture has been developed for the mechanical part of EAP transducers, as the foundation for platform development. A generic description of an EAP transducer forms the core of the high level product architecture...... the function of the EAP transducers to be changed, by basing the EAP transducers on a different combination of organ alternatives. A model providing an overview of the high level product architecture has been developed to support daily development and cooperation across development teams. The platform approach...

  9. High Level Radioactive Waste Management

    International Nuclear Information System (INIS)

    1991-01-01

    The proceedings of the second annual international conference on High Level Radioactive Waste Management, held on April 28--May 3, 1991, Las Vegas, Nevada, provides information on the current technical issue related to international high level radioactive waste management activities and how they relate to society as a whole. Besides discussing such technical topics as the best form of the waste, the integrity of storage containers, design and construction of a repository, the broader social aspects of these issues are explored in papers on such subjects as conformance to regulations, transportation safety, and public education. By providing this wider perspective of high level radioactive waste management, it becomes apparent that the various disciplines involved in this field are interrelated and that they should work to integrate their waste management activities. Individual records are processed separately for the data bases

  10. Unexpected brain finding in pre-autopsy postmortem CT.

    Science.gov (United States)

    Chatzaraki, Vasiliki; Bolliger, Stephan A; Thali, Michael J; Eggert, Sebastian; Ruder, Thomas D

    2017-09-01

    A case is presented in which pre-autopsy postmortem computed tomography (PMCT) revealed an unexpected brain abscess with a related frontal sinusitis and an erosion of the posterior wall of the frontal sinus. PMCT findings enabled the forensic pathologists to adapt protective measures during autopsy and protect their health from infection. Pre-autopsy PMCT has been also useful in the early differential diagnosis procedure. The complementary use of postmortem imaging and autopsy can improve the quality of forensic death investigations.

  11. Disposal of high level and intermediate level radioactive wastes

    International Nuclear Information System (INIS)

    Flowers, R.H.

    1991-01-01

    The waste products from the nuclear industry are relatively small in volume. Apart from a few minor gaseous and liquid waste streams, containing readily dispersible elements of low radiotoxicity, all these products are processed into stable solid packages for disposal in underground repositories. Because the volumes are small, and because radioactive wastes are latecomers on the industrial scene, a whole new industry with a world-wide technological infrastructure has grown up alongside the nuclear power industry to carry out the waste processing and disposal to very high standards. Some of the technical approaches used, and the Regulatory controls which have been developed, will undoubtedly find application in the future to the management of non-radioactive toxic wastes. The repository site outlined would contain even high-level radioactive wastes and spent fuels being contained without significant radiation dose rates to the public. Water pathway dose rates are likely to be lowest for vitrified high-level wastes with spent PWR fuel and intermediate level wastes being somewhat higher. (author)

  12. Effects of unexpected lateral mass placement on trunk loading in lifting

    NARCIS (Netherlands)

    van der Burg, J.C.E.; Kingma, I.; van Dieen, J.H.

    2003-01-01

    Study Design. A repeated measurements experiment of spinal loading in healthy subjects. Objectives. To test whether unexpected lateral mass placement increases low back loading and trunk movement when subjects are lifting a mass in upright posture. Summary of Background Data. Epidemiologic studies

  13. Lower incidence of unexpected in-hospital death after interprofessional implementation of a bedside track-and-trigger system

    DEFF Research Database (Denmark)

    Bunkenborg, Gitte; Samuelson, Karin Samuelsonkarin; Poulsen, Ingrid

    2014-01-01

    In-hospital patients may suffer unexpected death because of suboptimal monitoring. Early recognition of deviating physiological parameters may enable staff to prevent unexpected in-hospital death. The aim of this study was to evaluate short- and long-term effects of systematic interprofessional u...... of early warning scoring, structured observation charts, and clinical algorithms for bedside action....

  14. Effects of unexpected chords and of performer's expression on brain responses and electrodermal activity.

    Science.gov (United States)

    Koelsch, Stefan; Kilches, Simone; Steinbeis, Nikolaus; Schelinski, Stefanie

    2008-07-09

    There is lack of neuroscientific studies investigating music processing with naturalistic stimuli, and brain responses to real music are, thus, largely unknown. This study investigates event-related brain potentials (ERPs), skin conductance responses (SCRs) and heart rate (HR) elicited by unexpected chords of piano sonatas as they were originally arranged by composers, and as they were played by professional pianists. From the musical excerpts played by the pianists (with emotional expression), we also created versions without variations in tempo and loudness (without musical expression) to investigate effects of musical expression on ERPs and SCRs. Compared to expected chords, unexpected chords elicited an early right anterior negativity (ERAN, reflecting music-syntactic processing) and an N5 (reflecting processing of meaning information) in the ERPs, as well as clear changes in the SCRs (reflecting that unexpected chords also elicited emotional responses). The ERAN was not influenced by emotional expression, whereas N5 potentials elicited by chords in general (regardless of their chord function) differed between the expressive and the non-expressive condition. These results show that the neural mechanisms of music-syntactic processing operate independently of the emotional qualities of a stimulus, justifying the use of stimuli without emotional expression to investigate the cognitive processing of musical structure. Moreover, the data indicate that musical expression affects the neural mechanisms underlying the processing of musical meaning. Our data are the first to reveal influences of musical performance on ERPs and SCRs, and to show physiological responses to unexpected chords in naturalistic music.

  15. Effects of unexpected chords and of performer's expression on brain responses and electrodermal activity.

    Directory of Open Access Journals (Sweden)

    Stefan Koelsch

    Full Text Available BACKGROUND: There is lack of neuroscientific studies investigating music processing with naturalistic stimuli, and brain responses to real music are, thus, largely unknown. METHODOLOGY/PRINCIPAL FINDINGS: This study investigates event-related brain potentials (ERPs, skin conductance responses (SCRs and heart rate (HR elicited by unexpected chords of piano sonatas as they were originally arranged by composers, and as they were played by professional pianists. From the musical excerpts played by the pianists (with emotional expression, we also created versions without variations in tempo and loudness (without musical expression to investigate effects of musical expression on ERPs and SCRs. Compared to expected chords, unexpected chords elicited an early right anterior negativity (ERAN, reflecting music-syntactic processing and an N5 (reflecting processing of meaning information in the ERPs, as well as clear changes in the SCRs (reflecting that unexpected chords also elicited emotional responses. The ERAN was not influenced by emotional expression, whereas N5 potentials elicited by chords in general (regardless of their chord function differed between the expressive and the non-expressive condition. CONCLUSIONS/SIGNIFICANCE: These results show that the neural mechanisms of music-syntactic processing operate independently of the emotional qualities of a stimulus, justifying the use of stimuli without emotional expression to investigate the cognitive processing of musical structure. Moreover, the data indicate that musical expression affects the neural mechanisms underlying the processing of musical meaning. Our data are the first to reveal influences of musical performance on ERPs and SCRs, and to show physiological responses to unexpected chords in naturalistic music.

  16. Heat transfer in high-level waste management

    International Nuclear Information System (INIS)

    Dickey, B.R.; Hogg, G.W.

    1979-01-01

    Heat transfer in the storage of high-level liquid wastes, calcining of radioactive wastes, and storage of solidified wastes are discussed. Processing and storage experience at the Idaho Chemical Processing Plant are summarized for defense high-level wastes; heat transfer in power reactor high-level waste processing and storage is also discussed

  17. Fournier gangrene and unexpected death.

    Science.gov (United States)

    Bury, Danielle; Byard, Roger W

    2012-11-01

    Fournier gangrene represents a rare but progressive perineal infection that may result in rapid death. A 70-year-old man with poorly controlled diabetes mellitus and alcohol abuse is reported who was found unexpectedly dead. He had last been contacted the night before his death. At autopsy, the most striking finding was deep necrotic ulceration of the scrotum with exposure of underlying deep muscles and testicles, with blood cultures positive for Escherichia coli. Death was, therefore, attributed to necrotic ulceration/gangrene of the perineum (Fournier gangrene) that was due to E. coli sepsis with underlying contributing factors of diabetes mellitus and alcoholism. In addition there was morbid obesity (body mass index 46.9), cirrhosis of the liver, and marked focal coronary artery atherosclerosis with significant cardiomegaly. Fournier gangrene may be an extremely aggressive condition that can result in rapid death, as was demonstrated by the rapid progression in the reported case. © 2012 American Academy of Forensic Sciences.

  18. Next of kin’s experiences of sudden and unexpected death from stroke - a study of narratives

    Science.gov (United States)

    2013-01-01

    Background Death always evokes feelings in those close to the afflicted person. When death comes suddenly the time for preparation is minimal and the next of kin have to cope with the situation despite their own sorrow. The suddenness is found to be stressful for the next of kin and communication both with healthcare professionals and information about what has happened has been found helpful. The aim of this study was to illuminate the experiences of next of kin from the sudden and unexpected death of a relative from acute stroke. Methods Data was collected over a 12-month period in 2009–2010. Twelve next of kin of patients cared for in stroke units who died suddenly and unexpectedly from stroke were interviewed using a narrative method. The narratives were analyzed using narrative thematic analysis. Results Three themes emerged showing facets of next of kin’s experiences of a relative’s sudden and unexpected death from stroke: Divided feelings about the sudden and unexpected death; Perception of time and directed attention when keeping vigil; Contradictions and arbitrary memories when searching for understanding. Conclusions To have to live in the aftermath of severe stroke is absolute horror in people’s imagination and death is seen as the lesser of two evils. The sudden and unexpected death totally pervades the next of kin’s life, directs their attention to the dying person and even causes them to forget themselves and their own needs, and leads to difficulties in information intake. It is a challenge for the healthcare professionals to be able to identify the individual needs of the next of kin in this situation. PMID:23590246

  19. Complex and unexpected dynamics in simple genetic regulatory networks

    Science.gov (United States)

    Borg, Yanika; Ullner, Ekkehard; Alagha, Afnan; Alsaedi, Ahmed; Nesbeth, Darren; Zaikin, Alexey

    2014-03-01

    One aim of synthetic biology is to construct increasingly complex genetic networks from interconnected simpler ones to address challenges in medicine and biotechnology. However, as systems increase in size and complexity, emergent properties lead to unexpected and complex dynamics due to nonlinear and nonequilibrium properties from component interactions. We focus on four different studies of biological systems which exhibit complex and unexpected dynamics. Using simple synthetic genetic networks, small and large populations of phase-coupled quorum sensing repressilators, Goodwin oscillators, and bistable switches, we review how coupled and stochastic components can result in clustering, chaos, noise-induced coherence and speed-dependent decision making. A system of repressilators exhibits oscillations, limit cycles, steady states or chaos depending on the nature and strength of the coupling mechanism. In large repressilator networks, rich dynamics can also be exhibited, such as clustering and chaos. In populations of Goodwin oscillators, noise can induce coherent oscillations. In bistable systems, the speed with which incoming external signals reach steady state can bias the network towards particular attractors. These studies showcase the range of dynamical behavior that simple synthetic genetic networks can exhibit. In addition, they demonstrate the ability of mathematical modeling to analyze nonlinearity and inhomogeneity within these systems.

  20. Sudden unexpected death in children with a previously diagnosed cardiovascular disorder

    NARCIS (Netherlands)

    Polderman, Florens N.; Cohen, Joeri; Blom, Nico A.; Delhaas, Tammo; Helbing, Wim A.; Lam, Jan; Sobotka-Plojhar, Marta A.; Temmerman, Arno M.; Sreeram, Narayanswani

    2004-01-01

    BACKGROUND: It is known that children with previously diagnosed heart defects die suddenly. The causes of death are often unknown. OBJECTIVE: The aim of the study was to identify all infants and children within the Netherlands with previously diagnosed heart disease who had a sudden unexpected death

  1. Sudden unexpected death in children with a previously diagnosed cardiovascular disorder

    NARCIS (Netherlands)

    Polderman, F.N.; Cohen, Joeri; Blom, N.A.; Delhaas, T.; Helbing, W.A.; Lam, J.; Sobotka-Plojhar, M.A.; Temmerman, Arno M.; Sreeram, N.

    2004-01-01

    Background: It is known that children with previously diagnosed heart defects die suddenly. The causes of death are often unknown. Objective: The aim of the study was to identify all infants and children within the Netherlands with previously diagnosed heart disease who had a sudden unexpected death

  2. Recovering method for high level radioactive material

    International Nuclear Information System (INIS)

    Fukui, Toshiki

    1998-01-01

    Offgas filters such as of nuclear fuel reprocessing facilities and waste control facilities are burnt, and the burnt ash is melted by heating, and then the molten ashes are brought into contact with a molten metal having a low boiling point to transfer the high level radioactive materials in the molten ash to the molten metal. Then, only the molten metal is evaporated and solidified by drying, and residual high level radioactive materials are recovered. According to this method, the high level radioactive materials in the molten ashes are transferred to the molten metal and separated by the difference of the distribution rate of the molten ash and the molten metal. Subsequently, the molten metal to which the high level radioactive materials are transferred is heated to a temperature higher than the boiling point so that only the molten metal is evaporated and dried to be removed, and residual high level radioactive materials are recovered easily. On the other hand, the molten ash from which the high level radioactive material is removed can be discarded as ordinary industrial wastes as they are. (T.M.)

  3. Audit of radiology communication systems for critical, urgent, and unexpected significant findings.

    Science.gov (United States)

    Duncan, K A; Drinkwater, K J; Dugar, N; Howlett, D C

    2016-03-01

    To determine the compliance of UK radiology departments and trusts/healthcare organisations with National Patient Safety Agency and Royal College of Radiologist's published guidance on the communication of critical, urgent, and unexpected significant radiological findings. A questionnaire was sent to all UK radiology department audit leads asking for details of their current departmental policy regarding the issuing of alerts; use of automated electronic alert systems; methods of notification of clinicians of critical, urgent, and unexpected significant radiological findings; monitoring of results receipt; and examples of the more common types of serious pathologies for which alerts were issued. One hundred and fifty-four of 229 departments (67%) responded. Eighty-eight percent indicated that they had a policy in place for the communication of critical, urgent, and unexpected significant radiological findings. Only 34% had an automated electronic alert system in place and only 17% had a facility for service-wide electronic tracking of radiology reports. In only 11 departments with an electronic acknowledgement system was someone regularly monitoring the read rate. There is wide variation in practice across the UK with regard to the communication and monitoring of reports with many departments/trusts not fully compliant with published UK guidance. Despite the widespread use of electronic systems, only a minority of departments/trusts have and use electronic tracking to ensure reports have been read and acted upon. Copyright © 2015 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

  4. High-level-waste immobilization

    International Nuclear Information System (INIS)

    Crandall, J.L.

    1982-01-01

    Analysis of risks, environmental effects, process feasibility, and costs for disposal of immobilized high-level wastes in geologic repositories indicates that the disposal system safety has a low sensitivity to the choice of the waste disposal form

  5. Fatigue life analysis of unexpected failure in a lamellar TiAl alloy

    Energy Technology Data Exchange (ETDEWEB)

    Chan, K.S.

    1999-07-01

    Unexpected catastrophic failure occurred in specimens of a lamellar TiAl alloy tested by axial fatigue. The failure initiated at locations away from artificial defects introduced to the specimens as crack starters. Fractographic examination of the fracture surface revealed the presence of featureless, low-energy facets that suggested the catastrophic crack may have initiated in one or more large grains that cleaved on a cleavage plane or an interface. A crack growth analysis of fatigue life of the test specimens suggested that the catastrophic crack propagated at stress intensity levels below the large crack threshold. Furthermore, the catastrophic crack propagated at rates that were higher than the average rates exhibited by small cracks, as well as by the large crack under equivalent stress intensity ranges. Because of this, the conventional life prediction approach based on the large crack growth data grossly overpredicted the fatigue life.

  6. Four unexpected lanthanide coordination polymers involving in situ reaction of solvent N, N-Dimethylformamide

    International Nuclear Information System (INIS)

    Jin, Jun-Cheng; Tong, Wen-Quan; Fu, Ai-Yun; Xie, Cheng-Gen; Chang, Wen-Gui; Wu, Ju; Xu, Guang-Nian; Zhang, Ya-Nan; Li, Jun; Li, Yong; Yang, Peng-Qi

    2015-01-01

    Four unexpected 2D lanthanide coordination polymers have been synthesized through in situ reactions of DMF solvent under solvothermal conditions. The isostructural complexes 1–3 contain four types of 2 1 helical chains. While the Nd(III) ions are bridged through μ 2 -HIDC 2− and oxalate to form a 2D sheet along the bc plane without helical character in 4. Therefore, complex 1 exhibits bright red solid-state phosphorescence upon exposure to UV radiation at room temperature. - Graphical abstract: Four unexpected 2D lanthanide coordination polymers have been synthesized through in situ reactions of solvent DMF to formate acid or oxalic acid under solvothermal conditions. The isostructural complexes 1–3 contain four types of different 2 1 helical chains in the 2D layer and 1 exhibits bright red solid-state phosphorescence upon UV radiation. - Highlights: • Four unexpected 2D lanthanide coordination compounds have been synthesized through in situ reactions under solvothermal conditions. • The complexes 1–3 contain four types of 2 1 helical chains in the layer. • Complex 1 exhibits bright red solid-state phosphorescence upon exposure to UV radiation at room temperature

  7. Po-210 high levels in aquatic plants of the Carapebus sandbank, RJ, Brazil; Teores elevados de polonio-210 em plantas aquaticas da Restinga de Carapebus, RJ

    Energy Technology Data Exchange (ETDEWEB)

    Kelecom, Alphonse; Santos, Pedro Lopes dos; Gouvea, Rita de Cassis S.; Dutra, Iedo Ramos; Fevereiro, Paulo Cesar Ayres [Universidade Federal Fluminense, Niteroi, RJ (Brazil). Dept. de Biologia Geral

    1999-10-01

    {sup 210} Po concentration have been determined in one green alga and in five freshwater plants grown in a pond of the Carapebus restinga (state of Rio de Janeiro). The alga Chara sp showed elevated concentration of {sup 210} Po, similar to that observed in marine algae. All the other plants had the lowest concentration of {sup 210} Po in the stems and the highest in the roots. Intermediate values were observed in the leaves. The unexpected high concentration of {sup 210} Po in the roots, even superior to reported values for roots of plants from high radioactive background areas, must be due to the elevated levels of this radionuclide in associated soils that are known to be rich in humic organic material. There seem to have no translocation of this radionuclide from the roots to the other parts of the plants. (author)

  8. Falls-risk post-stroke: Examining contributions from paretic versus non paretic limbs to unexpected forward gait slips.

    Science.gov (United States)

    Kajrolkar, Tejal; Bhatt, Tanvi

    2016-09-06

    Community-dwelling stroke survivors show a high incidence of falls with unexpected external perturbations during dynamic activities like walking. Previous evidence has demonstrated the importance of compensatory stepping to restore dynamic stability in response to perturbations in hemiparetic stroke survivors. However, these studies were limited to either stance perturbations or perturbation induced under the unaffected limb. This study aimed to compare the differences, if any, between the non-paretic and paretic sides in dynamic stability and protective stepping strategies when exposed to unexpected external perturbation during walking. Twenty hemiparetic subjects experienced an unexpected forward slip during walking on the laboratory walkway either on the paretic (n=10) or the nonparetic limb (n=10). Both groups demonstrated a backward loss of balance with a compensatory stepping response, with the nonparetic-side slip group resorting mainly to an aborted step response (60%) and the paretic-side slip group mainly exhibiting a recovery step response (90%). Although both groups showed an equal incidence of falls, the nonparetic-side slip group demonstrated a higher stability at recovery step touchdown, resulting from lower perturbation magnitudes (slip displacement and velocity) compared to the paretic-side slip group. The results indicate that the paretic side had difficulty initiating and executing a successful stepping response (nonparetic-side slip) and also in reactive limb control while in stance (paretic-side slip). Based on these results it is suggested that intervention strategies for fall-prevention in chronic stroke survivors should focus on paretic limb training for both reactive stepping and weight bearing for improving balance control for recovery from unpredictable perturbations during dynamic activities such as walking. Copyright © 2016. Published by Elsevier Ltd.

  9. A High-Voltage Level Tolerant Transistor Circuit

    NARCIS (Netherlands)

    Annema, Anne J.; Geelen, Godefridus Johannes Gertrudis Maria

    2001-01-01

    A high-voltage level tolerant transistor circuit, comprising a plurality of cascoded transistors, including a first transistor (T1) operatively connected to a high-voltage level node (3) and a second transistor (T2) operatively connected to a low-voltage level node (2). The first transistor (T1)

  10. Unpredictable Root Canal Morphology: Expect the Unexpected

    Directory of Open Access Journals (Sweden)

    Sohez J Makani

    2015-01-01

    Full Text Available Background: A maxillary first molar with more than four canals is an interesting example of anatomic variations, especially when two of these canals are detected, with separate apical foramen in the distal root. The inability to locate the unexpected canals of various anatomical configuration and subsequently treat them , may lead to therapeutic failures. Endodontic retreatment is usually the modality of choice in such cases. This report describes a case of a maxillary first molar with five canals (two mesial canals in mesial root, two distal canals in two distal roots and a palatal canal in palatal root. Additionally it shows a rare anatomic configuration and emphasizes the importance of identifying additional canals.

  11. Dysfunctional Brain Networking among Autonomic Regulatory Structures in Temporal Lobe Epilepsy Patients at High Risk of Sudden Unexpected Death in Epilepsy

    Directory of Open Access Journals (Sweden)

    Luke A. Allen

    2017-10-01

    Full Text Available BackgroundSudden unexpected death in epilepsy (SUDEP is common among young people with epilepsy. Individuals who are at high risk of SUDEP exhibit regional brain structural and functional connectivity (FC alterations compared with low-risk patients. However, less is known about network-based FC differences among critical cortical and subcortical autonomic regulatory brain structures in temporal lobe epilepsy (TLE patients at high risk of SUDEP.Methods32 TLE patients were risk-stratified according to the following clinical criteria: age of epilepsy onset, duration of epilepsy, frequency of generalized tonic–clonic seizures, and presence of nocturnal seizures, resulting in 14 high-risk and 18 low-risk cases. Resting-state functional magnetic resonance imaging (rs-fMRI signal time courses were extracted from 11 bilateral cortical and subcortical brain regions involved in autonomic and other regulatory processes. After computing all pairwise correlations, FC matrices were analyzed using the network-based statistic. FC strength among the 11 brain regions was compared between the high- and low-risk patients. Increases and decreases in FC were sought, using high-risk > low-risk and low-risk > high-risk contrasts (with covariates age, gender, lateralization of epilepsy, and presence of hippocampal sclerosis.ResultsHigh-risk TLE patients showed a subnetwork with significantly reduced FC (t = 2.5, p = 0.029 involving the thalamus, brain stem, anterior cingulate, putamen and amygdala, and a second subnetwork with significantly elevated FC (t = 2.1, p = 0.031, which extended to medial/orbital frontal cortex, insula, hippocampus, amygdala, subcallosal cortex, brain stem, thalamus, caudate, and putamen.ConclusionTLE patients at high risk of SUDEP showed widespread FC differences between key autonomic regulatory brain regions compared to those at low risk. The altered FC revealed here may help to shed light on the functional

  12. Dysfunctional Brain Networking among Autonomic Regulatory Structures in Temporal Lobe Epilepsy Patients at High Risk of Sudden Unexpected Death in Epilepsy.

    Science.gov (United States)

    Allen, Luke A; Harper, Ronald M; Kumar, Rajesh; Guye, Maxime; Ogren, Jennifer A; Lhatoo, Samden D; Lemieux, Louis; Scott, Catherine A; Vos, Sjoerd B; Rani, Sandhya; Diehl, Beate

    2017-01-01

    Sudden unexpected death in epilepsy (SUDEP) is common among young people with epilepsy. Individuals who are at high risk of SUDEP exhibit regional brain structural and functional connectivity (FC) alterations compared with low-risk patients. However, less is known about network-based FC differences among critical cortical and subcortical autonomic regulatory brain structures in temporal lobe epilepsy (TLE) patients at high risk of SUDEP. 32 TLE patients were risk-stratified according to the following clinical criteria: age of epilepsy onset, duration of epilepsy, frequency of generalized tonic-clonic seizures, and presence of nocturnal seizures, resulting in 14 high-risk and 18 low-risk cases. Resting-state functional magnetic resonance imaging (rs-fMRI) signal time courses were extracted from 11 bilateral cortical and subcortical brain regions involved in autonomic and other regulatory processes. After computing all pairwise correlations, FC matrices were analyzed using the network-based statistic. FC strength among the 11 brain regions was compared between the high- and low-risk patients. Increases and decreases in FC were sought, using high-risk > low-risk and low-risk > high-risk contrasts (with covariates age, gender, lateralization of epilepsy, and presence of hippocampal sclerosis). High-risk TLE patients showed a subnetwork with significantly reduced FC ( t  = 2.5, p  = 0.029) involving the thalamus, brain stem, anterior cingulate, putamen and amygdala, and a second subnetwork with significantly elevated FC ( t  = 2.1, p  = 0.031), which extended to medial/orbital frontal cortex, insula, hippocampus, amygdala, subcallosal cortex, brain stem, thalamus, caudate, and putamen. TLE patients at high risk of SUDEP showed widespread FC differences between key autonomic regulatory brain regions compared to those at low risk. The altered FC revealed here may help to shed light on the functional correlates of autonomic disturbances in epilepsy

  13. A propensity score analysis of the impact of surgical intervention on unexpected 30-day readmission following admission for subdural hematoma.

    Science.gov (United States)

    Franko, Lynze R; Sheehan, Kyle M; Roark, Christopher D; Joseph, Jacob R; Burke, James F; Rajajee, Venkatakrishna; Williamson, Craig A

    2017-12-22

    OBJECTIVE Subdural hematoma (SDH) is a common disease that is increasingly being managed nonoperatively. The all-cause readmission rate for SDH has not previously been described. This study seeks to describe the incidence of unexpected 30-day readmission in a cohort of patients admitted to an academic neurosurgical center. Additionally, the relationship between operative management, clinical outcome, and unexpected readmission is explored. METHODS This is an observational study of 200 consecutive adult patients with SDH admitted to the neurosurgical ICU of an academic medical center. Demographic information, clinical characteristics, and treatment strategies were compared between readmitted and nonreadmitted patients. Multivariable logistic regression, weighted by the inverse probability of receiving surgery using propensity scores, was used to evaluate the association between operative management and unexpected readmission. RESULTS Of 200 total patients, 18 (9%) died during hospitalization and were not included in the analysis. Overall, 48 patients (26%) were unexpectedly readmitted within 30 days. Sixteen patients (33.3%) underwent SDH evacuation during their readmission. Factors significantly associated with unexpected readmission were nonoperative management (72.9% vs 54.5%, p = 0.03) and female sex (50.0% vs 32.1%, p = 0.03). In logistic regression analysis weighted by the inverse probability of treatment and including likely confounders, surgical management was not associated with likelihood of a good outcome at hospital discharge, but was associated with significantly reduced odds of unexpected readmission (OR 0.19, 95% CI 0.08-0.49). CONCLUSIONS Over 25% of SDH patients admitted to an academic neurosurgical ICU were unexpectedly readmitted within 30 days. Nonoperative management does not affect outcome at hospital discharge but is significantly associated with readmission, even when accounting for the probability of treatment by propensity score weighted

  14. Unexpected Anal Squamous Cells Carcinoma after Open Hemorrhoidectomy

    Directory of Open Access Journals (Sweden)

    Navarra Luca

    2015-01-01

    Full Text Available We report a case of unexpected anal squamous cells carcinoma found in hemorrhoidectomy specimen. The patient had a 3-year history of prolapsing hemorrhoids. A prolapsing hemorrhoid was present at eleven o’clock in lithotomy. Milligan-Morgan was performed and gross examination of the specimen was unremarkable. Histopathologic evaluation showed noninvasive squamous cells carcinoma. The present case report evidences the opportunity of routine histopathologic analysis of hemorrhoidal specimens particularly in case of long-standing prolapse. Questions arise in the option of those techniques where no specimens are collected or tissue is excised far from deceased area.

  15. Unexpected death holograms: Animitas urban appeal in Chile

    Directory of Open Access Journals (Sweden)

    Lautaro Ojeda Ledesma

    2011-01-01

    Full Text Available This paper aims at performing an integral analysis of the relation between popular religiousness and urban space in Chilean animitas [little shrines] practices. In order to do this, we propose a multipurpose analysis scheme, holding the concept of "unexpected death hologram". This scheme puts forward three supplementary classifications: animita as a holographic subject, as a holographic object and as a holographic place. Finally, these three classifications supplemented by interviews and topologic analyses show almost all the sociospatial factors present in this practice, accounting for the urban importance that this type of popular practice has

  16. Alopecia associated with unexpected leakage from electron cone

    Energy Technology Data Exchange (ETDEWEB)

    Wen, B.C.; Pennington, E.C.; Hussey, D.H.; Jani, S.K.

    1989-06-01

    Excessive irradiation due to unexpected leakage was found on a patient receiving electron beam therapy. The cause of this leakage was analyzed and the amount of leakage was measured for different electron beam energies. The highest leakage occurred with a 6 x 6 cm cone using a 12 MeV electron beam. The leakage dose measured along the side of the cone could be as great as 40%. Until the cones are modified or redesigned, it is advised that all patient setups be carefully reviewed to assure that no significant patient areas are in the side scatter region.

  17. Precision grip responses to unexpected rotational perturbations scale with axis of rotation.

    Science.gov (United States)

    De Gregorio, Michael; Santos, Veronica J

    2013-04-05

    It has been established that rapid, pulse-like increases in precision grip forces ("catch-up responses") are elicited by unexpected translational perturbations and that response latency and strength scale according to the direction of linear slip relative to the hand as well as gravity. To determine if catch-up responses are elicited by unexpected rotational perturbations and are strength-, axis-, and/or direction-dependent, we imposed step torque loads about each of two axes which were defined relative to the subject's hand: the distal-proximal axis away from and towards the subject's palm, and the grip axis which connects the two fingertips. Precision grip responses were dominated initially by passive mechanics and then by active, unimodal catch-up responses. First dorsal interosseous activity, marking the start of the catch-up response, began 71-89 ms after the onset of perturbation. The onset latency, shape, and duration (217-231 ms) of the catch-up response were not affected by the axis, direction, or magnitude of the rotational perturbation, while strength was scaled by axis of rotation and slip conditions. Rotations about the grip axis that tilted the object away from the palm and induced rotational slip elicited stronger catch-up responses than rotations about the distal-proximal axis that twisted the object between the digits. To our knowledge, this study is the first to investigate grip responses to unexpected torque loads and to show characteristic, yet axis-dependent, catch-up responses for conditions other than pure linear slip. Copyright © 2013 Elsevier Ltd. All rights reserved.

  18. High-level waste processing and disposal

    International Nuclear Information System (INIS)

    Crandall, J.L.; Krause, H.; Sombret, C.; Uematsu, K.

    1984-01-01

    The national high-level waste disposal plans for France, the Federal Republic of Germany, Japan, and the United States are covered. Three conclusions are reached. The first conclusion is that an excellent technology already exists for high-level waste disposal. With appropriate packaging, spent fuel seems to be an acceptable waste form. Borosilicate glass reprocessing waste forms are well understood, in production in France, and scheduled for production in the next few years in a number of other countries. For final disposal, a number of candidate geological repository sites have been identified and several demonstration sites opened. The second conclusion is that adequate financing and a legal basis for waste disposal are in place in most countries. Costs of high-level waste disposal will probably add about 5 to 10% to the costs of nuclear electric power. The third conclusion is less optimistic. Political problems remain formidable in highly conservative regulations, in qualifying a final disposal site, and in securing acceptable transport routes

  19. High levels of Porphyromonas gingivalis-induced immunoglobulin G2 are associated with lower high-density lipoprotein levels in chronic periodontitis.

    Science.gov (United States)

    Ardila, Carlos M; Guzmán, Isabel C

    2016-11-01

    To investigate the association between the presence of Porphyromonas gingivalis-induced immunoglobulin G antibodies and the high-density lipoprotein (HDL) level. A total of 108 individuals were examined. The presence of P. gingivalis was detected using primers designed to target the 16S rRNA gene sequence. Peripheral blood was collected from each subject to determine the levels of P. gingivalis-induced IgG1 and IgG2 serum antibodies. The HDL levels were determined using fully enzymatic methods. A higher proportion of periodontitis patients had high levels of P. gingivalis-induced IgG1 and IgG2, and the proportion of subjects with a HDL level of chronic periodontitis patients. In the unadjusted regression model, the presence of high levels of P. gingivalis-induced IgG2 was associated with a HDL level of periodontitis patients with high levels of P. gingivalis-induced IgG2 showed 3.2 more chances of having pathological HDL levels (odds ratio = 3.2, 95% confidence interval = 1.2-9.8). High levels of P. gingivalis-induced IgG2 were associated with low HDL concentrations in patients with periodontitis, which suggests that the response of the host to periodontal infection may play an important role in the pathogenesis of cardiovascular diseases. © 2015 Wiley Publishing Asia Pty Ltd.

  20. The unexpected decarbonylation of ionized 2,3-pentanedione and related diketones

    Science.gov (United States)

    Wang, Xian; Holmes, John L.

    2006-03-01

    The fragmentation of the 2,3-pentanedione radical cation gives rise to an unexpected composite metastable ion peak, m/z 72, resulting from the isobaric losses of CO and C2H4. These two fragmentation channels are energetically competitive (i.e., the transition states have similar energies). The two processes yield [CH3C(O)CH2CH3]+ and [CH3C(OH)CO]+, respectively. The latter new ion, which is produced by a McLafferty rearrangement, has [Delta]fH° = 604 kJ/mol, obtained from G3 calculations. The four competing processes for metastable [CH3COCOCH2CH3]+, the (intense) losses of CH3CO, CH3CH2CO and the weak losses of C2H4 and CO and their transition states were placed on a potential energy surface computed at the G3 level of theory. The homologous ionized diketone 2,3-butanedione also displays the decarbonylation channel and 3,4-hexanedione loses CO and C2H4.

  1. Teach Students to Dig for Understanding Using an Unexpected Technological Shovel

    Science.gov (United States)

    Lake, Susan E. L.

    2004-01-01

    Online genealogy tools is an unexpected resource as these tools not only serve valuable for genealogy research, but also can be used by students to learn about their country's past and learn to use primary materials to draw conclusions. Some of these Online sources like the 1880 census available at www.ancestry.com, www.thepastwhispers.com, which…

  2. All Intimate Grammars Leak: Reflections on "Indian Languages in Unexpected Places"

    Science.gov (United States)

    Kroskrity, Paul V.

    2011-01-01

    In this discussion of a set of studies that fits the trope of "Indian Languages in Unexpected Places," I explore the obvious necessity of developing a relevant notion of linguistic "leakage" following a famous image from the writings of the linguistic anthropologist Edward Sapir. Though in its original use, the concept applied more to the order of…

  3. Adaptive designs for dose-finding in non-cancer phase II trials: influence of early unexpected outcomes.

    Science.gov (United States)

    Resche-Rigon, Matthieu; Zohar, Sarah; Chevret, Sylvie

    2008-01-01

    In non-cancer phase II trials, dose-finding trials are usually carried out using fixed designs, in which several doses including a placebo are randomly distributed to patients. However, in certain vulnerable populations, such as neonates or infants, there is an heightened requirement for safety, precluding randomization. To estimate the minimum effective dose of a new drug from a non-cancer phase II trial, we propose the use of adaptive designs like the Continual Reassessment Method (CRM). This approach estimates the dose closest to some target response, and has been shown to be unbiased and efficient in cancer phase I trials. Based on a motivating example, we point out the individual influence of first outliers in this setting. A weighted version of the CRM is proposed as a theoretical benchmark to control for these outliers. Using simulations, we illustrate how this approach provides further insight into the behavior of the CRM. When dealing with low targets like a 10% failure rate, the CRM appears unable to rapidly overcome an early unexpected outcome. This behavior persisted despite changing the inference (Bayesian or likelihood), underlying dose-response model (though slightly improved using the power model), and the number of patients enrolled at each dose level. The choices for initial guesses of failure rates, the vague prior for the model parameter, and the log-log shape of weights can appear somewhat arbitrary. In phase II dose-finding studies in which failure targets are below 20%, the CRM appears quite sensitive to first unexpected outcomes. Using a power model for dose-response improves some behavior if the trial is started at the first dose level and includes at least three to five patients at the starting dose before applying the CRM allocation rule.

  4. High-Level Application Framework for LCLS

    Energy Technology Data Exchange (ETDEWEB)

    Chu, P; Chevtsov, S.; Fairley, D.; Larrieu, C.; Rock, J.; Rogind, D.; White, G.; Zalazny, M.; /SLAC

    2008-04-22

    A framework for high level accelerator application software is being developed for the Linac Coherent Light Source (LCLS). The framework is based on plug-in technology developed by an open source project, Eclipse. Many existing functionalities provided by Eclipse are available to high-level applications written within this framework. The framework also contains static data storage configuration and dynamic data connectivity. Because the framework is Eclipse-based, it is highly compatible with any other Eclipse plug-ins. The entire infrastructure of the software framework will be presented. Planned applications and plug-ins based on the framework are also presented.

  5. 75 FR 67015 - Unexpected Urgent Refugee And Migration Needs Resulting From Flooding InPakistan

    Science.gov (United States)

    2010-11-01

    ... September 3, 2010 Unexpected Urgent Refugee And Migration Needs Resulting From Flooding InPakistan... humanitarian needs resulting from recent devastating flooding in Pakistan. You are authorized and directed to...

  6. A subset of osteoblasts expressing high endogenous levels of PPARgamma switches fate to adipocytes in the rat calvaria cell culture model.

    Directory of Open Access Journals (Sweden)

    Yuji Yoshiko

    2010-07-01

    Full Text Available Understanding fate choice and fate switching between the osteoblast lineage (ObL and adipocyte lineage (AdL is important to understand both the developmental inter-relationships between osteoblasts and adipocytes and the impact of changes in fate allocation between the two lineages in normal aging and certain diseases. The goal of this study was to determine when during lineage progression ObL cells are susceptible to an AdL fate switch by activation of endogenous peroxisome proliferator-activated receptor (PPARgamma.Multiple rat calvaria cells within the ObL developmental hierarchy were isolated by either fractionation on the basis of expression of alkaline phosphatase or retrospective identification of single cell-derived colonies, and treated with BRL-49653 (BRL, a synthetic ligand for PPARgamma. About 30% of the total single cell-derived colonies expressed adipogenic potential (defined cytochemically when BRL was present. Profiling of ObL and AdL markers by qRT-PCR on amplified cRNA from over 160 colonies revealed that BRL-dependent adipogenic potential correlated with endogenous PPARgamma mRNA levels. Unexpectedly, a significant subset of relatively mature ObL cells exhibited osteo-adipogenic bipotentiality. Western blotting and immunocytochemistry confirmed that ObL cells co-expressed multiple mesenchymal lineage determinants (runt-related transcription factor 2 (Runx2, PPARgamma, Sox9 and MyoD which localized in the cytoplasm initially, and only Runx2 translocated to the nucleus during ObL progression. Notably, however, some cells exhibited both PPARgamma and Runx2 nuclear labeling with concomitant upregulation of expression of their target genes with BRL treatment.We conclude that not only immature but a subset of relatively mature ObL cells characterized by relatively high levels of endogenous PPARgamma expression can be switched to the AdL. The fact that some ObL cells maintain capacity for adipogenic fate selection even at relatively

  7. Simultaneous repair of abdominal aortic aneurysm and resection of unexpected, associated abdominal malignancies.

    Science.gov (United States)

    Illuminati, Giulio; Calio', Francesco G; D'Urso, Antonio; Lorusso, Riccardo; Ceccanei, Gianluca; Vietri, Francesco

    2004-12-15

    The management of unexpected intra-abdominal malignancy, discovered at laparotomy for elective treatment of an abdominal aortic aneurysm (AAA), is controversial. It is still unclear whether both conditions should be treated simultaneously or a staged approach is to be preferred. To contribute in improving treatment guidelines, we retrospectively reviewed the records of patients undergoing laparotomy for elective AAA repair. From January 1994 to March 2003, 253 patients underwent elective, trans-peritoneal repair of an AAA. In four patients (1.6%), an associated, unexpected neoplasm was detected at abdominal exploration, consisting of one renal, one gastric, one ileal carcinoid, and one ascending colon tumor. All of them were treated at the same operation, after aortic repair and careful isolation of the prosthetic graft. The whole series' operative mortality was 3.6%. None of the patients simultaneously treated for AAA and tumor resection died in the postoperative period. No graft-related infections were observed. Simultaneous treatment of AAA and tumor did not prolong significantly the mean length of stay in the hospital, compared to standard treatment of AAA alone. Except for malignancies of organs requiring major surgical resections, simultaneous AAA repair and resection of an associated, unexpected abdominal neoplasm can be safely performed, in most of the patients, sparing the need for a second procedure. Endovascular grafting of the AAA can be a valuable tool in simplifying simultaneous treatment, or in staging the procedures with a very short delay.

  8. General Algorithm (High level)

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. General Algorithm (High level). Iteratively. Use Tightness Property to remove points of P1,..,Pi. Use random sampling to get a Random Sample (of enough points) from the next largest cluster, Pi+1. Use the Random Sampling Procedure to approximate ci+1 using the ...

  9. Unexpectedly high uptake of palladium by bituminous coals

    Energy Technology Data Exchange (ETDEWEB)

    Lakatos, J. [Research Lab. for Mining Chemistry, Hungarian Academy of Sciences, Miskolc-Egyetemvaros (Hungary); Brown, S.D.; Snape, C.E. [Univ. of Strathclyde, Dept. of Pure and Applied Chemistry, Glasgow (United Kingdom)

    1997-12-31

    The uptake of palladium as a conversion catalyst onto coals of different rank was investigated. Palladium fixation occurs by a different mode to that for alkaline earth and first row transition metals. Therefore, the dispersion of relatively high concentration of palladium by an ion sorption process is even possible for bituminous coals. (orig.)

  10. Incidentally found and unexpected tumors discovered by MRI examination for temporomandibular joint arthrosis

    International Nuclear Information System (INIS)

    Yanagi, Yoshinobu; Asaumi, Jun-ichi; Maki, Yuu; Murakami, Jun; Hisatomi, Miki; Matsuzaki, Hidenobu; Konouchi, Hironobu; Honda, Yosutoshi; Kishi, Kanji

    2003-01-01

    We examined the frequency of incidentally found or unexpected tumors discovered at the time of magnetic resonance imaging (MRI) examinations in the temporomandibular joint (TMJ) region for patients with suspicion of TMJ arthrosis. Five MR images (T1-weighted transverse scout image and proton density and T2-weighted oblique sagittal images at the open and closed mouth) were acquired. In 2776 MRI examinations of TMJ arthrosis, two tumors were discovered. They consisted of an adenoid cystic carcinoma in the deep portion of the parotid gland, and a malignant tumor extending from the infratemporal fossa to the parapharyngeal space. The rate of incidentally founded or unexpected tumors in TMJ examinations was low (0.072%), but the two tumors found were malignant tumors, and therefore, scout image should be carefully examined, not only used for positing the slice

  11. Incidentally found and unexpected tumors discovered by MRI examination for temporomandibular joint arthrosis

    Energy Technology Data Exchange (ETDEWEB)

    Yanagi, Yoshinobu; Asaumi, Jun-ichi E-mail: asaumi@md.okayama-u.ac.jp; Maki, Yuu; Murakami, Jun; Hisatomi, Miki; Matsuzaki, Hidenobu; Konouchi, Hironobu; Honda, Yosutoshi; Kishi, Kanji

    2003-07-01

    We examined the frequency of incidentally found or unexpected tumors discovered at the time of magnetic resonance imaging (MRI) examinations in the temporomandibular joint (TMJ) region for patients with suspicion of TMJ arthrosis. Five MR images (T1-weighted transverse scout image and proton density and T2-weighted oblique sagittal images at the open and closed mouth) were acquired. In 2776 MRI examinations of TMJ arthrosis, two tumors were discovered. They consisted of an adenoid cystic carcinoma in the deep portion of the parotid gland, and a malignant tumor extending from the infratemporal fossa to the parapharyngeal space. The rate of incidentally founded or unexpected tumors in TMJ examinations was low (0.072%), but the two tumors found were malignant tumors, and therefore, scout image should be carefully examined, not only used for positing the slice.

  12. 76 FR 14271 - Unexpected Urgent Refugee and Migration Needs Related to Libya

    Science.gov (United States)

    2011-03-16

    ... March 7, 2011 Unexpected Urgent Refugee and Migration Needs Related to Libya Memorandum for the... States, including section 2(c)(1) of the Migration and Refugee Assistance Act of 1962 (the ``Act''), as... million from the United States Emergency Refugee and Migration Assistance Fund, for the purpose of meeting...

  13. Partitioning of high level liquid waste: experiences in plant level adoption

    International Nuclear Information System (INIS)

    Manohar, Smitha; Kaushik, C.P.

    2016-01-01

    High Level Radioactive Wastes are presently vitrified in borosilicate matrices in all our back end facilities in our country. This is in accordance with internationally endorsed methodology for the safe management of high level radioactive wastes. Recent advancements in the field of partitioning technology in our group, has presented us with an opportunity to have a fresh perspective on management of high level liquid radioactive wastes streams, that emanate from reprocessing operations. This paper will highlight our experiences with respect to both partitioning studies and vitrification practices, with a focus on waste volume reduction for final disposal. Incorporation of this technique has led to the implementation of the concept of recovering wealth from waste, a marked decrease on the load of disposal in deep geological repositories and serve as a step towards the vision of transmutation of long lived radionuclides

  14. A novel reducing graphene/polyaniline/cuprous oxide composite hydrogel with unexpected photocatalytic activity for the degradation of Congo red

    International Nuclear Information System (INIS)

    Miao, Jie; Xie, Anjian; Li, Shikuo; Huang, Fangzhi; Cao, Juan; Shen, Yuhua

    2016-01-01

    Graphical abstract: Excellent photocatalytic activity of the RGO/PANI/Cu_2O composite hydrogel for CR degradation under UV–vis light irradiation. - Highlights: • The RGO/PANI/Cu_2O composite hydrogel was first synthesized via a facile method. • Photocatalytic performance was studied under UV–vis light. • The ternary composite hydrogel shows unexpected photocatalytic activity. • A possible photocatalysis mechanism was illustrated. - Abstract: In this work, a novel reducing graphene/polyaniline/cuprous oxide (RGO/PANI/Cu_2O) composite hydrogel with a 3D porous network has been successfully prepared via a one-pot method in the presence of cubic Cu_2O nanoparticles. The as-synthesized ternary composites hydrogel shows unexpected photocatalytic activity such that Congo red (CR) degradation efficiency can reaches 97.91% in 20 min under UV–vis light irradiation, which is much higher than that of either the single component (Cu_2O nanoparticles), or two component systems (RGO/Cu_2O composite hydrogel and PANI/Cu_2O nanocomposites). Furthermore, the ternary composite hydrogel exhibits high stability and do not show any significant loss after five recycles. Such outstanding photocatalytic activity of the RGO/PANI/Cu_2O composite hydrogel was ascribed to the high absorption ability of the product for CR and the synergic effect among RGO, PANI and Cu_2O in photocatalytic process. The product of this work would provide a new sight for the construction of UV–vis light responsive photocatalyst with high performance.

  15. Audit of radiology communication systems for critical, urgent, and unexpected significant findings

    International Nuclear Information System (INIS)

    Duncan, K.A.; Drinkwater, K.J.; Dugar, N.; Howlett, D.C.

    2016-01-01

    Aim: To determine the compliance of UK radiology departments and trusts/healthcare organisations with National Patient Safety Agency and Royal College of Radiologist's published guidance on the communication of critical, urgent, and unexpected significant radiological findings. Materials and methods: A questionnaire was sent to all UK radiology department audit leads asking for details of their current departmental policy regarding the issuing of alerts; use of automated electronic alert systems; methods of notification of clinicians of critical, urgent, and unexpected significant radiological findings; monitoring of results receipt; and examples of the more common types of serious pathologies for which alerts were issued. Results: One hundred and fifty-four of 229 departments (67%) responded. Eighty-eight percent indicated that they had a policy in place for the communication of critical, urgent, and unexpected significant radiological findings. Only 34% had an automated electronic alert system in place and only 17% had a facility for service-wide electronic tracking of radiology reports. In only 11 departments with an electronic acknowledgement system was someone regularly monitoring the read rate. Conclusion: There is wide variation in practice across the UK with regard to the communication and monitoring of reports with many departments/trusts not fully compliant with published UK guidance. Despite the widespread use of electronic systems, only a minority of departments/trusts have and use electronic tracking to ensure reports have been read and acted upon. - Highlights: • UK wide audit of communication of significant radiology results. • 88% of departments have a communication policy in place. • 34% of departments have an automated electronic alert system. • 17% of Trusts have facility for service wide electronic tracking of radiology reports.

  16. Unexpected observations after mapping LongSAGE tags to the human genome

    Directory of Open Access Journals (Sweden)

    Duret Laurent

    2007-05-01

    Full Text Available Abstract Background SAGE has been used widely to study the expression of known transcripts, but much less to annotate new transcribed regions. LongSAGE produces tags that are sufficiently long to be reliably mapped to a whole-genome sequence. Here we used this property to study the position of human LongSAGE tags obtained from all public libraries. We focused mainly on tags that do not map to known transcripts. Results Using a published error rate in SAGE libraries, we first removed the tags likely to result from sequencing errors. We then observed that an unexpectedly large number of the remaining tags still did not match the genome sequence. Some of these correspond to parts of human mRNAs, such as polyA tails, junctions between two exons and polymorphic regions of transcripts. Another non-negligible proportion can be attributed to contamination by murine transcripts and to residual sequencing errors. After filtering out our data with these screens to ensure that our dataset is highly reliable, we studied the tags that map once to the genome. 31% of these tags correspond to unannotated transcripts. The others map to known transcribed regions, but many of them (nearly half are located either in antisense or in new variants of these known transcripts. Conclusion We performed a comprehensive study of all publicly available human LongSAGE tags, and carefully verified the reliability of these data. We found the potential origin of many tags that did not match the human genome sequence. The properties of the remaining tags imply that the level of sequencing error may have been under-estimated. The frequency of tags matching once the genome sequence but not in an annotated exon suggests that the human transcriptome is much more complex than shown by the current human genome annotations, with many new splicing variants and antisense transcripts. SAGE data is appropriate to map new transcripts to the genome, as demonstrated by the high rate of cross

  17. Predictors of Placement in Lower Level versus Higher Level High School Mathematics

    Science.gov (United States)

    Archbald, Doug; Farley-Ripple, Elizabeth N.

    2012-01-01

    Educators and researchers have long been interested in determinants of access to honors level and college prep courses in high school. Factors influencing access to upper level mathematics courses are particularly important because of the hierarchical and sequential nature of this subject and because students who finish high school with only lower…

  18. High-Level Development of Multiserver Online Games

    Directory of Open Access Journals (Sweden)

    Frank Glinka

    2008-01-01

    Full Text Available Multiplayer online games with support for high user numbers must provide mechanisms to support an increasing amount of players by using additional resources. This paper provides a comprehensive analysis of the practically proven multiserver distribution mechanisms, zoning, instancing, and replication, and the tasks for the game developer implied by them. We propose a novel, high-level development approach which integrates the three distribution mechanisms seamlessly in today's online games. As a possible base for this high-level approach, we describe the real-time framework (RTF middleware system which liberates the developer from low-level tasks and allows him to stay at high level of design abstraction. We explain how RTF supports the implementation of single-server online games and how RTF allows to incorporate the three multiserver distribution mechanisms during the development process. Finally, we describe briefly how RTF provides manageability and maintenance functionality for online games in a grid context with dynamic resource allocation scenarios.

  19. Long-term high-level waste technology program

    International Nuclear Information System (INIS)

    1980-04-01

    The Department of Energy (DOE) is conducting a comprehensive program to isolate all US nuclear wastes from the human environment. The DOE Office of Nuclear Energy - Waste (NEW) has full responsibility for managing the high-level wastes resulting from defense activities and additional responsiblity for providing the technology to manage existing commercial high-level wastes and any that may be generated in one of several alternative fuel cycles. Responsibilities of the Three Divisions of DOE-NEW are shown. This strategy document presents the research and development plan of the Division of Waste Products for long-term immobilization of the high-level radioactive wastes resulting from chemical processing of nuclear reactor fuels and targets. These high-level wastes contain more than 99% of the residual radionuclides produced in the fuels and targets during reactor operations. They include essentially all the fission products and most of the actinides that were not recovered for use

  20. Investigating Teachers' Appraisal of Unexpected Moments and Underlying Values: An Exploratory Case in the Context of Changing Mathematics Classroom Discourse

    Science.gov (United States)

    Cavanna, Jillian M.; Herbel-Eisenmann, Beth; Seah, Wee Tiong

    2015-01-01

    This article provides an exploratory case study that examines what one teacher indicated as unexpected as she worked to become more purposeful about her classroom discourse practices. We found that she highlighted three areas as being unexpected: (1) aspects of lesson enactment; (2) characteristics of student learning and (3) her own…

  1. High-Level Radioactive Waste.

    Science.gov (United States)

    Hayden, Howard C.

    1995-01-01

    Presents a method to calculate the amount of high-level radioactive waste by taking into consideration the following factors: the fission process that yields the waste, identification of the waste, the energy required to run a 1-GWe plant for one year, and the uranium mass required to produce that energy. Briefly discusses waste disposal and…

  2. High-level radioactive wastes

    International Nuclear Information System (INIS)

    Grissom, M.C.

    1982-10-01

    This bibliography contains 812 citations on high-level radioactive wastes included in the Department of Energy's Energy Data Base from January 1981 through July 1982. These citations are to research reports, journal articles, books, patents, theses, and conference papers from worldwide sources. Five indexes are provided: Corporate Author, Personal Author, Subject, Contract Number, and Report Number

  3. Effects of Muscle Fatigue, Creep, and Musculoskeletal Pain on Neuromuscular Responses to Unexpected Perturbation of the Trunk: A Systematic Review.

    Science.gov (United States)

    Abboud, Jacques; Lardon, Arnaud; Boivin, Frédéric; Dugas, Claude; Descarreaux, Martin

    2016-01-01

    spinae reflex latency in patients with chronic LBP in comparison with healthy controls following an unexpected trunk perturbation. Conclusion: The literature provides some evidence with regard to trunk adaptions in a context of spinal instability. However, most of the evidence was inconclusive due to a high methodological heterogeneity between the studies.

  4. Process for solidifying high-level nuclear waste

    Science.gov (United States)

    Ross, Wayne A.

    1978-01-01

    The addition of a small amount of reducing agent to a mixture of a high-level radioactive waste calcine and glass frit before the mixture is melted will produce a more homogeneous glass which is leach-resistant and suitable for long-term storage of high-level radioactive waste products.

  5. Characteristics of solidified high-level waste products

    International Nuclear Information System (INIS)

    1979-01-01

    The object of the report is to contribute to the establishment of a data bank for future preparation of codes of practice and standards for the management of high-level wastes. The work currently in progress on measuring the properties of solidified high-level wastes is being studied

  6. Disposal of high-level waste from nuclear power plants in Denmark. Salt dome investigations. v.4

    International Nuclear Information System (INIS)

    1981-01-01

    The present report deals with construction, operation and sealing of disposal facilities for high-level waste in a salt dome. It is volume 4 of five volumes that together constitute the final report on the Danish utilities' salt dome investigations. The safety investigations were carried out for a deep-hole disposal facility located in the salt dome on Mors. In principle the results of the investigations also apply to a shaft/mine disposal facility. The facility is designed for the disposal of vitrified high-level waste in the shape of glass canisters. There is a low concentration of waste in each canister, approx. 10%. Furthermore, it was selected to place the waste in an intermediate storage for about 40 years prior to its final disposal. Consequently, heat generation in the waste at the time of final disposal will be modest, resulting in low temperature increase in the salt. As an example, the highest temperature increase will be approx. 40 deg. C. and it will occur at the edge of the hole five years after disposal has taken place. Prior to disposal, the glass canisters are encased in steel casks with 15 cm thick walls. Three canisters are placed in each cask, and 215 casks are stacked on top on one another in each deep-hole from a depth of 1200 m to 2500 m underground. The additional encasing is designed to protect the glass from dissolution should any brine reach the disposal facility. Furthermore, the steel cask protects the glass canisters against pressure from the wall of the hole. The technical design of the disposal facility gives it a considerable safety margin against unexpected events. The investigations proved Cretaceous strata to constitute an effective secondary barrier that would prevent radioactive matter from travelling from the underlying disposal facility to the biosphere. (BP)

  7. Hunting for unexpected post-translational modifications by spectral library searching with tier-wise scoring.

    Science.gov (United States)

    Ma, Chun Wai Manson; Lam, Henry

    2014-05-02

    Discovering novel post-translational modifications (PTMs) to proteins and detecting specific modification sites on proteins is one of the last frontiers of proteomics. At present, hunting for post-translational modifications remains challenging in widely practiced shotgun proteomics workflows due to the typically low abundance of modified peptides and the greatly inflated search space as more potential mass shifts are considered by the search engines. Moreover, most popular search methods require that the user specifies the modification(s) for which to search; therefore, unexpected and novel PTMs will not be detected. Here a new algorithm is proposed to apply spectral library searching to the problem of open modification searches, namely, hunting for PTMs without prior knowledge of what PTMs are in the sample. The proposed tier-wise scoring method intelligently looks for unexpected PTMs by allowing mass-shifted peak matches but only when the number of matches found is deemed statistically significant. This allows the search engine to search for unexpected modifications while maintaining its ability to identify unmodified peptides effectively at the same time. The utility of the method is demonstrated using three different data sets, in which the numbers of spectrum identifications to both unmodified and modified peptides were substantially increased relative to a regular spectral library search as well as to another open modification spectral search method, pMatch.

  8. Unexpected properties of Radim-type radon monitors

    International Nuclear Information System (INIS)

    Plch, J.; Burian, I.; Jilek, K.; Vosahlik, J.

    2004-01-01

    The results of numerous experiments carried out using Radim-type monitors are summarized. The monitor, which is based on collection of ions on the surface of a semiconductor detector in an electric field, exhibits enormous efficiency in collecting ions, which attains a value of 70% in the optimum case. The collection efficiency exhibits low dependence on the humidity: the efficiency decreases by 7.4% when the humidity changes from 50 to 90%. The dependence on the humidity is linear to 10% - in contradiction with the published results. The work gives the experimentally determined decreases in the presence of smoke and VOCs, which are acceptable even when the smoke and VOC concentrations are enormous. The results are analyzed and an attempt was made to theoretically explain these unexpected results. (author)

  9. Patterns of unexpected in-hospital deaths: a root cause analysis

    Directory of Open Access Journals (Sweden)

    Curry J Paul

    2011-02-01

    Full Text Available Abstract Background Respiratory alarm monitoring and rapid response team alerts on hospital general floors are based on detection of simple numeric threshold breaches. Although some uncontrolled observation trials in select patient populations have been encouraging, randomized controlled trials suggest that this simplistic approach may not reduce the unexpected death rate in this complex environment. The purpose of this review is to examine the history and scientific basis for threshold alarms and to compare thresholds with the actual pathophysiologic patterns of evolving death which must be timely detected. Methods The Pubmed database was searched for articles relating to methods for triggering rapid response teams and respiratory alarms and these were contrasted with the fundamental timed pathophysiologic patterns of death which evolve due to sepsis, congestive heart failure, pulmonary embolism, hypoventilation, narcotic overdose, and sleep apnea. Results In contrast to the simplicity of the numeric threshold breach method of generating alerts, the actual patterns of evolving death are complex and do not share common features until near death. On hospital general floors, unexpected clinical instability leading to death often progresses along three distinct patterns which can be designated as Types I, II and III. Type I is a pattern comprised of hyperventilation compensated respiratory failure typical of congestive heart failure and sepsis. Here, early hyperventilation and respiratory alkalosis can conceal the onset of instability. Type II is the pattern of classic CO2 narcosis. Type III occurs only during sleep and is a pattern of ventilation and SPO2 cycling caused by instability of ventilation and/or upper airway control followed by precipitous and fatal oxygen desaturation if arousal failure is induced by narcotics and/or sedation. Conclusion The traditional threshold breach method of detecting instability on hospital wards was not

  10. High-level waste immobilization program: an overview

    International Nuclear Information System (INIS)

    Bonner, W.R.

    1979-09-01

    The High-Level Waste Immobilization Program is providing technology to allow safe, affordable immobilization and disposal of nuclear waste. Waste forms and processes are being developed on a schedule consistent with national needs for immobilization of high-level wastes stored at Savannah River, Hanford, Idaho National Engineering Laboratory, and West Valley, New York. This technology is directly applicable to high-level wastes from potential reprocessing of spent nuclear fuel. The program is removing one more obstacle previously seen as a potential restriction on the use and further development of nuclear power, and is thus meeting a critical technological need within the national objective of energy independence

  11. National high-level waste systems analysis report

    Energy Technology Data Exchange (ETDEWEB)

    Kristofferson, K.; Oholleran, T.P.; Powell, R.H.

    1995-09-01

    This report documents the assessment of budgetary impacts, constraints, and repository availability on the storage and treatment of high-level waste and on both existing and pending negotiated milestones. The impacts of the availabilities of various treatment systems on schedule and throughput at four Department of Energy sites are compared to repository readiness in order to determine the prudent application of resources. The information modeled for each of these sites is integrated with a single national model. The report suggests a high-level-waste model that offers a national perspective on all high-level waste treatment and storage systems managed by the Department of Energy.

  12. National high-level waste systems analysis report

    International Nuclear Information System (INIS)

    Kristofferson, K.; Oholleran, T.P.; Powell, R.H.

    1995-09-01

    This report documents the assessment of budgetary impacts, constraints, and repository availability on the storage and treatment of high-level waste and on both existing and pending negotiated milestones. The impacts of the availabilities of various treatment systems on schedule and throughput at four Department of Energy sites are compared to repository readiness in order to determine the prudent application of resources. The information modeled for each of these sites is integrated with a single national model. The report suggests a high-level-waste model that offers a national perspective on all high-level waste treatment and storage systems managed by the Department of Energy

  13. Critical Neural Substrates for Correcting Unexpected Trajectory Errors and Learning from Them

    Science.gov (United States)

    Mutha, Pratik K.; Sainburg, Robert L.; Haaland, Kathleen Y.

    2011-01-01

    Our proficiency at any skill is critically dependent on the ability to monitor our performance, correct errors and adapt subsequent movements so that errors are avoided in the future. In this study, we aimed to dissociate the neural substrates critical for correcting unexpected trajectory errors and learning to adapt future movements based on…

  14. Overview: Defense high-level waste technology program

    International Nuclear Information System (INIS)

    Shupe, M.W.; Turner, D.A.

    1987-01-01

    Defense high-level waste generated by atomic energy defense activities is stored on an interim basis at three U.S. Department of Energy (DOE) operating locations; the Savannah River Plant in South Carolina, the Hanford Site in Washington, and the Idaho National Engineering Laboratory in Idaho. Responsibility for the permanent disposal of this waste resides with DOE's Office of Defense Waste and Transportation Management. The objective of the Defense High-Level Wast Technology Program is to develop the technology for ending interim storage and achieving permanent disposal of all U.S. defense high-level waste. New and readily retrievable high-level waste are immobilized for disposal in a geologic repository. Other high-level waste will be stabilized in-place if, after completion of the National Environmental Policy Act (NEPA) process, it is determined, on a site-specific basis, that this option is safe, cost effective and environmentally sound. The immediate program focus is on implementing the waste disposal strategy selected in compliance with the NEPA process at Savannah River, while continuing progress toward development of final waste disposal strategies at Hanford and Idaho. This paper presents an overview of the technology development program which supports these waste management activities and an assessment of the impact that recent and anticipated legal and institutional developments are expected to have on the program

  15. Disposal of high-level radioactive waste

    International Nuclear Information System (INIS)

    Glasby, G.P.

    1977-01-01

    Although controversy surrounding the possible introduction of nuclear power into New Zealand has raised many points including radiation hazards, reactor safety, capital costs, sources of uranium and earthquake risks on the one hand versus energy conservation and alternative sources of energy on the other, one problem remains paramount and is of global significance - the storage and dumping of the high-level radioactive wastes of the reactor core. The generation of abundant supplies of energy now in return for the storage of these long-lived highly radioactive wastes has been dubbed the so-called Faustian bargain. This article discusses the growth of the nuclear industry and its implications to high-level waste disposal particularly in the deep-sea bed. (auth.)

  16. 40 CFR 227.30 - High-level radioactive waste.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false High-level radioactive waste. 227.30...-level radioactive waste. High-level radioactive waste means the aqueous waste resulting from the operation of the first cycle solvent extraction system, or equivalent, and the concentrated waste from...

  17. Unexpected rates of chromosomal instabilities and alterations of hormone levels in Namibian uranium miners

    International Nuclear Information System (INIS)

    Zaire, R.; Notter, M.; Thiel, E.

    1997-01-01

    A common problem in determining the health consequences of radiation exposure is factoring out other carcinogenic influences. The conditions in Namibia provide a test case for distinguishing the effects of long-term low-dose exposure to uranium from the other environmental factors because of good air quality and the lack of other industries with negative health effects. Present records indicate a much higher prevalence of cancer among male workers in the open-pit uranium mine in Namibia compared with the general population. The objective of the present study was to determine whether long-term exposure to low doses of uranium increases the risk of a biological radiation damage which would lead to malignant diseases and to derive a dose-response model for these miners. To investigate this risk, we measured uranium excretion in urine, neutrophil counts and the serum level of FSH, LH and testosterone and analyzed chromosome aberrations in whole blood cells using fluorescence in situ hybridization. A representative cohort of 75 non-smoking, HIV-negative miners was compared to a control group of 31 individuals with no occupational history in mining. A sixfold increase in uranium excretion among the miners compared to the controls was recorded (P < 0.001). Furthermore, we determined a significant reduction in testosterone levels (P < 0.008) and neutrophil count (P < 0.0001). Most remarkably, cells with multiple aberrations such as open-quotes rogueclose quotes cells were observed for the first time in miners; these cells had previously been found only after short-term high-dose radiation exposure, e.g. from the Hiroshima atomic bomb or the Chernobyl accident. 19 refs., 1 fig., 3 tabs

  18. Heavy Metals, Cardiovascular Disease, and the Unexpected Benefits of Edetate Disodium Chelation Therapy

    Science.gov (United States)

    Lamas, Gervasio A.; Navas-Acien, Ana; Mark, Daniel B.; Lee, Kerry L.

    2016-01-01

    This review summarizes evidence from 2 lines of research previously thought unrelated: the unexpectedly positive results of the Trial to Assess Chelation Therapy (TACT), and a body of epidemiological data showing that accumulation of biologically active metals, such as lead and cadmium, is an important risk factor for cardiovascular disease. Considering these 2 areas of work together may lead to the identification of new, modifiable risk factors for atherosclerotic cardiovascular disease. We examine the history of chelation up through the report of TACT. We then describe work connecting higher metal levels in the body with the future risk of cardiovascular disease. We conclude by presenting a brief overview of a newly planned National Institutes of Health trial, TACT2, in which we will attempt to replicate the findings of TACT and to establish that removal of toxic metal stores from the body is a plausible mechanistic explanation for the benefits of edetate disodium treatment. PMID:27199065

  19. Sudden unexpected death under acute influence of cannabis.

    Science.gov (United States)

    Hartung, Benno; Kauferstein, Silke; Ritz-Timme, Stefanie; Daldrup, Thomas

    2014-04-01

    The acute toxicity of cannabinoids is said to be low and there is little public awareness of the potentially hazardous cardiovascular effects of cannabis, e.g. marked increase in heart rate or supine blood pressure. We describe the cases of two young, putative healthy men who died unexpectedly under the acute influence of cannabinoids. To our knowledge, these are the first cases of suspected fatal cannabis intoxications where full postmortem investigations, including autopsy, toxicological, histological, immunohistochemical and genetical examinations, were carried out. The results of these examinations are presented. After exclusion of other causes of death we assume that the young men experienced fatal cardiovascular complications evoked by smoking cannabis. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  20. Safe sleep practices in a New Zealand community and development of a Sudden Unexpected Death in Infancy (SUDI) risk assessment instrument

    OpenAIRE

    Galland, Barbara C; Gray, Andrew; Sayers, Rachel M; Heath, Anne-Louise M; Lawrence, Julie; Taylor, Rachael; Taylor, Barry J

    2014-01-01

    Background Interventions to prevent sudden unexpected death in infancy (SUDI) have generally been population wide interventions instituted after case?control studies identified specific childcare practices associated with sudden death. While successful overall, in New Zealand (NZ), the rates are still relatively high by international comparison. This study aims to describe childcare practices related to SUDI prevention messages in a New Zealand community, and to develop and explore the utilit...

  1. Gamma rays made on Earth have unexpectedly high energies

    International Nuclear Information System (INIS)

    Miller, Johanna

    2011-01-01

    Terrestrial gamma-ray flashes (TGFs) are the source of the highest-energy nonanthropogenic photons produced on Earth. Associated with thunder-storms - and in fact, with individual lightning discharges - they are presumed to be the bremsstrahlung produced when relativistic electrons, accelerated by the storms' strong electric fields, collide with air molecules some 10-20 km above sea level. The TGFs last up to a few milliseconds and contain photons with energies on the order of MeV.

  2. Heavy Metals, Cardiovascular Disease, and the Unexpected Benefits of Chelation Therapy.

    Science.gov (United States)

    Lamas, Gervasio A; Navas-Acien, Ana; Mark, Daniel B; Lee, Kerry L

    2016-05-24

    This review summarizes evidence from 2 lines of research previously thought to be unrelated: the unexpectedly positive results of TACT (Trial to Assess Chelation Therapy), and a body of epidemiological data showing that accumulation of biologically active metals, such as lead and cadmium, is an important risk factor for cardiovascular disease. Considering these 2 areas of work together may lead to the identification of new, modifiable risk factors for atherosclerotic cardiovascular disease. We examine the history of chelation up through the report of TACT. We then describe work connecting higher metal levels in the body with the future risk of cardiovascular disease. We conclude by presenting a brief overview of a newly planned National Institutes of Health trial, TACT2, in which we will attempt to replicate the findings of TACT and to establish that removal of toxic metal stores from the body is a plausible mechanistic explanation for the benefits of edetate disodium treatment. Copyright © 2016 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

  3. Unexpectedly high leprosy seroprevalence detected using a random surveillance strategy in midwestern Brazil: A comparison of ELISA and a rapid diagnostic test.

    Science.gov (United States)

    Frade, Marco Andrey C; de Paula, Natália A; Gomes, Ciro M; Vernal, Sebastian; Bernardes Filho, Fred; Lugão, Helena B; de Abreu, Marilda M M; Botini, Patrícia; Duthie, Malcolm S; Spencer, John S; Soares, Rosa Castália F R; Foss, Norma T

    2017-02-01

    Leprosy diagnosis is mainly based on clinical evaluation, although this approach is difficult, especially for untrained physicians. We conducted a temporary campaign to detect previously unknown leprosy cases in midwestern Brazil and to compare the performance of different serological tests. A mobile clinic was stationed at the main bus terminal in Brasília, Brazil. Volunteers were quizzed and given a clinical exam to allow categorization as either patients, known contacts of patients or non-contacts, and blood was collected to determine anti-PGL-I and anti-LID-1 antibody titers by ELISA and by the NDO-LID rapid test. New cases of leprosy and the impact of performing this broad random surveillance strategy were evaluated. Accuracy values and concordance between the test results were evaluated among all groups. Four hundred thirty-four individuals were evaluated, and 44 (10.1%) were diagnosed with leprosy. Borderline forms were the most frequent presentation. Both tests presented higher positivity in those individuals with multibacillary disease. Serological tests demonstrated specificities arround 70% for anti-PGL-1 and anti-LID ELISA; and arround 40% for NDO-LID. Sensitivities ranged from 48 to 62%. A substantial agreement between NDO-LID and ELISA with concomitant positive results was found within leprosy patients (Kappa index = 0.79 CI95% 0.36-1.22). The unexpectedly high leprosy prevalence in this population indicates ongoing community-based exposure to Mycobacterium leprae antigens and high rates of subclinical infection. All tests showed low specificity and sensitivity values and therefore cannot be considered for use as stand-alone diagnostics. Rather, considering their positivity among MB patients and non-patients, these tests can be considered effective tools for screening and identifying individuals at high risk who might benefit from regular monitoring.

  4. Unexpected photoreactivation of Vibrio harveyi bacteria living in ionization environment

    International Nuclear Information System (INIS)

    Alifano, P.; Tala, A.; Tredici, S. M.; Nassisi, V.; Siciliano, M. V.

    2011-01-01

    Bacteria undergoing environmental effects is extremely interesting for structural, mechanistic, and evolutionary implications. Luminescent bacteria that have evolved in a specific ambient have developed particular responses and their behavior can give us new suggestions on the task and production of luciferina proteins. To analyze the UV interaction under controlled laboratory conditions, we used photoluminescent bacterial strains belonging to a new species evolutionarily close to Vibrio harveyi sampled from a coastal cave with a high radon content that generates ionizing radiation. The survival of the bacterial strains was analyzed, in the light and in the dark, following a variety of genotoxic treatments including UV radiation exposure. The strains were irradiated by a germicide lamp. The results demonstrated that most of the strains exhibited a low rate of survival after the UV exposure. After irradiation by visible light following the UV exposure, all strains showed a high capability of photoreactivation when grown. This capability was quite unexpected because these bacteria were sampled from a dark ambient without UV radiation. This leads us to hypothesize that the photoreactivation in these bacteria might have been evolved to repair DNA lesions also induced by different radiation sources other than UV (e.g., x-ray) and that the luminescent bacteria might use their own light emission to carry out the photoreactivation. The high capability of photoreactivation of these bacteria was also justified by the results of deconvolution. The deconvolution was applied to the emission spectra and it was able to show evidence of different light peaks. The presence of the visible peak could control the photolysis enzyme.

  5. Children and Trauma: Unexpected Resistance and Justice in Film and Drawings

    Directory of Open Access Journals (Sweden)

    Cheri M. Robinson

    2018-02-01

    Full Text Available This transnational study examines representations of and by children—whether literal wounds, psychological ones, or wounds transmitted through drawings—that manifest their capacity for unexpected resistance and justice. It considers the Mexican-American director Guillermo del Toro’s use of hauntings and wounds to explore violence during the 1936–1939 Spanish Civil War in the film El espinazo del diablo [The Devil’s Backbone] (2001 and its intersections on strategic and theoretical levels with the traumatic in archival children’s drawings produced during the 1976–1983 Argentine military dictatorship. The drawings illustrate the violence perpetrated against the child artists’ families and were produced in exile for the human rights organization COSOFAM. Utilizing diverse theories from film and trauma studies, among others, this article analyzes key scenes in El espinazo exhibiting commonalities with representations of traumatic violence in the children’s drawings, revealing that, in fiction and in fact, a strategic “showing” of the traumatic wound is designed to remind others of the imperative to intervene in situations of extreme violence, to appeal to/for justice, and to effectively testify from the inside.

  6. A novel reducing graphene/polyaniline/cuprous oxide composite hydrogel with unexpected photocatalytic activity for the degradation of Congo red

    Energy Technology Data Exchange (ETDEWEB)

    Miao, Jie; Xie, Anjian; Li, Shikuo; Huang, Fangzhi; Cao, Juan; Shen, Yuhua, E-mail: yhshen@ahu.edu.cn

    2016-01-01

    Graphical abstract: Excellent photocatalytic activity of the RGO/PANI/Cu{sub 2}O composite hydrogel for CR degradation under UV–vis light irradiation. - Highlights: • The RGO/PANI/Cu{sub 2}O composite hydrogel was first synthesized via a facile method. • Photocatalytic performance was studied under UV–vis light. • The ternary composite hydrogel shows unexpected photocatalytic activity. • A possible photocatalysis mechanism was illustrated. - Abstract: In this work, a novel reducing graphene/polyaniline/cuprous oxide (RGO/PANI/Cu{sub 2}O) composite hydrogel with a 3D porous network has been successfully prepared via a one-pot method in the presence of cubic Cu{sub 2}O nanoparticles. The as-synthesized ternary composites hydrogel shows unexpected photocatalytic activity such that Congo red (CR) degradation efficiency can reaches 97.91% in 20 min under UV–vis light irradiation, which is much higher than that of either the single component (Cu{sub 2}O nanoparticles), or two component systems (RGO/Cu{sub 2}O composite hydrogel and PANI/Cu{sub 2}O nanocomposites). Furthermore, the ternary composite hydrogel exhibits high stability and do not show any significant loss after five recycles. Such outstanding photocatalytic activity of the RGO/PANI/Cu{sub 2}O composite hydrogel was ascribed to the high absorption ability of the product for CR and the synergic effect among RGO, PANI and Cu{sub 2}O in photocatalytic process. The product of this work would provide a new sight for the construction of UV–vis light responsive photocatalyst with high performance.

  7. Unexpected improvement in core autism spectrum disorder symptoms after long-term treatment with probiotics

    Directory of Open Access Journals (Sweden)

    Enzo Grossi

    2016-08-01

    Full Text Available Objectives: Autism spectrum disorder is a neurodevelopmental condition that typically displays socio-communicative impairment as well as restricted stereotyped interests and activities, in which gastrointestinal disturbances are commonly reported. We report the case of a boy with Autism Spectrum Disorder (ASD diagnosis, severe cognitive disability and celiac disease in which an unexpected improvement of autistic core symptoms was observed after four months of probiotic treatment. Method: The case study refers to a 12 years old boy with ASD and severe cognitive disability attending the Villa Santa Maria Institute in resident care since 2009. Diagnosis of ASDs according to DSM-V criteria was confirmed by ADOS-2 assessment (Autism Diagnostic Observation Schedule. The medication used was VSL#3, a multi-strain mixture of ten probiotics. The treatment lasted 4 weeks followed by a four month follow-up. The rehabilitation program and the diet was maintained stable in the treatment period and in the follow up. ADOS-2 was assessed six times: two times before starting treatment; two times during the treatment and two times after interruption of the treatment. Results: The probiotic treatment reduced the severity of abdominal symptoms as expected but an improvement in Autistic core symptoms was unexpectedly clinically evident already after few weeks from probiotic treatment start. The score of Social Affect domain of ADOS improved changing from 20 to 18 after two months treatment with a further reduction of 1 point in the following two months. The level 17 of severity remained stable in the follow up period. It is well known that ADOS score does not fluctuate spontaneously along time in ASD and is absolutely stable. Conclusions: The appropriate use of probiotics deserves further research, which hopefully will open new avenues in the fight against ASD.

  8. Unexpected improvement in core autism spectrum disorder symptoms after long-term treatment with probiotics.

    Science.gov (United States)

    Grossi, Enzo; Melli, Sara; Dunca, Delia; Terruzzi, Vittorio

    2016-01-01

    Autism spectrum disorder is a neurodevelopmental condition that typically displays socio-communicative impairment as well as restricted stereotyped interests and activities, in which gastrointestinal disturbances are commonly reported. We report the case of a boy with Autism Spectrum Disorder (ASD) diagnosis, severe cognitive disability and celiac disease in which an unexpected improvement of autistic core symptoms was observed after four months of probiotic treatment. The case study refers to a 12 years old boy with ASD and severe cognitive disability attending the Villa Santa Maria Institute in resident care since 2009. Diagnosis of ASDs according to DSM-V criteria was confirmed by ADOS-2 assessment (Autism Diagnostic Observation Schedule). The medication used was VSL#3, a multi-strain mixture of ten probiotics. The treatment lasted 4 weeks followed by a four month follow-up. The rehabilitation program and the diet was maintained stable in the treatment period and in the follow up. ADOS-2 was assessed six times: two times before starting treatment; two times during the treatment and two times after interruption of the treatment. The probiotic treatment reduced the severity of abdominal symptoms as expected but an improvement in Autistic core symptoms was unexpectedly clinically evident already after few weeks from probiotic treatment start. The score of Social Affect domain of ADOS improved changing from 20 to 18 after two months treatment with a further reduction of 1 point in the following two months. The level 17 of severity remained stable in the follow up period. It is well known that ADOS score does not fluctuate spontaneously along time in ASD and is absolutely stable. The appropriate use of probiotics deserves further research, which hopefully will open new avenues in the fight against ASD.

  9. Preserved scleral patch graft for unexpected extreme scleral thinning found at the scleral buckling procedure: A case report

    Directory of Open Access Journals (Sweden)

    Spela Stunf

    2011-01-01

    Full Text Available Pre-existing scleral pathology is an important risk factor for globe rupture during scleral buckling procedures. We report here, the surgical management of an unexpected scleral pathology found at the scleral buckling procedure in a retinal detachment patient. A 77-year-old white female with retinal detachment underwent a scleral buckling procedure. The surgery was converted into a scleral graft procedure, as extreme scleral thinning was found intraoperatively. An alcohol-preserved donor sclera graft was used. The second surgery for definitive retinal alignment was performed two weeks later. The presented case of an unexpected scleral pathology in a retinal detachment patient was managed with a combination of scleral grafting and pars plana vitrectomy, without any major complications. The anatomical outcome was excellent and the scleral rupture was prevented; the visual outcome was satisfactory. A conversion of the scleral buckling procedure into a scleral graft procedure has proved to be safe and effective for unexpected scleral pathology.

  10. Tourism Stocks in Times of Crises: An Econometric Investigation of Unexpected Non-macroeconomic Factors

    NARCIS (Netherlands)

    A. Zopiatis (Anastasios); C.S. Savva (Christos); N. Lambertides (Neophytos); M.J. McAleer (Michael)

    2017-01-01

    textabstractFollowing the recent terrorist attacks in Paris, the European media emphatically pronounced that billions of Euros were wiped from tourism related stocks. The theoretical relationship of the industry with such unexpected non-macro incidents received moderate academic coverage.

  11. Integrated Solid Earth Science: the right place and time to discover the unexpected? (Arthur Holmes Medal Lecture)

    Science.gov (United States)

    Cloetingh, Sierd

    2013-04-01

    The fascination of learning more about the way system Earth operates has driven generations of Earth scientists. This has been the case for early pioneers such as Arthur Holmes, focusing on the geological record in continental settings, as well as for the founding fathers of plate tectonics, who built upon the results of exploring the ocean floor. Two years ago we celebrated the centenary of the discovery by Mohorovicic of the seismic discontinuity that separates the crust from the mantle, which now carries his name. Reading the rocks and mapping the (sub)surface of the Earth has provided the foundation for a great deal of what we conceptually pursue today in developing and validating coupled deep Earth and surface processes. The unexpected is probably characterizing most of my scientific career. It started in 1968 when, as a student, entering the geology program of Groningen University headed by Professor Philip Kuenen, a pioneer in marine geology and sedimentology, the textbook of Arthur Holmes just happened to be my first purchase. It was during those years that plate tectonics drastically changed everything we were learning. I was also privileged to enter a few years later as an MSc student the Utrecht geophysics school at a time where Nico Vlaar as a young professor was developing a vigorous research program with a focus on seismology, attracting and stimulating many talented students. When he and Rinus Wortel started research on Tectonophysics in Utrecht, I decided to go for a PhD research project tackling the problem of the initiation of subduction, a first order problem in geodynamics, with still many aspects to be resolved. This research and the joint work with Rinus Wortel on modeling intraplate stresses in the Faralon, Nazca and Indo-Australian plates led quite unexpectedly to exploring, together with Kurt Lambeck, intraplate stress fluctuations in the lithosphere as possible tectonic causes for the origin of third-order cycles in relative sea-level

  12. Frequency, severity and causes of unexpected allergic reactions to food: A systematic literature review

    NARCIS (Netherlands)

    Versluis, A.; Knulst, A.C.; Kruizinga, A.G.; Michelsen, A.; Houben, G.F.; Baumert, J.L.; Os-Medendorp, H. van

    2015-01-01

    Summary: Food allergic patients have to deal with an avoidance diet. Confusing labelling terms or precautionary labels can result in misinterpretation and risk-taking behaviour. Even those patients that strictly adhere to their diet experience (sometimes severe) unexpected allergic reactions to

  13. Frequency, severity and causes of unexpected allergic reactions to food : A systematic literature review

    NARCIS (Netherlands)

    Versluis, A.; Knulst, A. C.; Kruizinga, A. G.; Michelsen, A.; Houben, G. F.; Baumert, J. L.; van Os-Medendorp, H.

    2015-01-01

    Summary: Food allergic patients have to deal with an avoidance diet. Confusing labelling terms or precautionary labels can result in misinterpretation and risk-taking behaviour. Even those patients that strictly adhere to their diet experience (sometimes severe) unexpected allergic reactions to

  14. Sudden and unexpected childhood deaths investigated at the Pretoria Medico-Legal Laboratory, South Africa, 2007 - 2011.

    Science.gov (United States)

    Van Deventer, B S; Rossouw, S H; Du Toit-Prinsloo, L

    2016-09-06

     Sudden and unexpected death is well known to occur in infants, and although sudden deaths are less frequent after the first birthday, they still account for a significant proportion of childhood deaths. In 2009, 1.9% of the total deaths in the USA were childhood deaths. In South Africa (SA) this proportion was much higher at 11.85%. According to the law, sudden and unexpected deaths are generally investigated as unnatural deaths. Establishing an exact underlying anatomical cause of death will depend on available resources and can be difficult in a substantial proportion of cases.  A retrospective descriptive case audit was conducted at the Pretoria Medico-Legal Laboratory (PMLL), SA, from 1 January 2007 through to 31 December 2011. All children aged 1 - 18 years who died suddenly and unexpectedly were included.  Ninety-eight cases were identified, which constituted nearly 1% of total admissions to the PMLL. The majority of the deaths were of children aged 1 - 5 years, and the male/female ratio was 1.04:1. In the largest proportion of cases (n=28, 28.6%), the medicolegal investigation, including autopsy and ancillary investigations, did not establish an underlying anatomical cause of death. In the cases where a cause of death was established, pneumonia was the most common diagnosis (n=22, 22.4%).  The fact that the cause of the largest proportion of deaths could not be ascertained emphasises the need for consideration of additional investigative techniques, such as molecular/genetic screening, which have provided an underlying cause of death in a significant number of cases in other countries. There is a lack of published research on the causes and incidence of sudden unexpected deaths in children in SA, and further research in this area is needed.

  15. Sudden unexpected death in infancy in Denmark

    DEFF Research Database (Denmark)

    Winkel, Bo Gregers; Holst, Anders Gaarsdal; Theilade, Juliane

    2011-01-01

    Abstract Background. Incidence of sudden unexpected death in infancy (SUDI) and sudden infant death syndrome (SIDS) differs among studies and non-autopsied cases are difficult to assess. Objectives. To investigate causes of sudden death in infancy in a nationwide setting. Validate the use...... of the ICD-10 code for SIDS (R95) in the Danish Cause of Death registry. Design. A retrospective analysis of all infant deaths (death certificates and autopsy reports were read. Results. We identified 192 SUDI cases (10% of total deaths, 0.42 per 1000 births......) with autopsy performed in 87% of cases. In total, 49% of autopsied SUDI cases were defined as SIDS (5% of all deaths, 0.22 per 1000 births); Cardiac cause of death was denoted in 24% of cases. The Danish Cause of Death Registry misclassified 30% of SIDS cases. Conclusions. A large proportion of infant deaths...

  16. The creative use of unexpected responses in the hypnotherapy of patients with conversion disorders

    NARCIS (Netherlands)

    Moene, F.C.; Hoogduin, C.A.L.

    1999-01-01

    In a previously completed empirical study examining the use of hypnosis in a comprehensive treatment program with 85 patients who suffered motor conversion symptoms, 16 patients were reported by their therapists to have had unusual and unexpected responses during hypnosis. This article summarizes

  17. Unexpected Symmetry in the Nodal Structure of the He Atom

    International Nuclear Information System (INIS)

    Bressanini, Dario; Reynolds, Peter J.

    2005-01-01

    The nodes of even simple wave functions are largely unexplored. Motivated by their importance to quantum simulations of fermionic systems, we have found unexpected symmetries in the nodes of several atoms and molecules. Here, we report on helium. We find that in both ground and excited states the nodes have simple forms. In particular, they have higher symmetry than the wave functions they come from. It is of great interest to understand the source of these new symmetries. For the quantum simulations that motivated the study, these symmetries may help circumvent the fermion sign problem

  18. Handling and storage of conditioned high-level wastes

    International Nuclear Information System (INIS)

    1983-01-01

    This report deals with certain aspects of the management of one of the most important wastes, i.e. the handling and storage of conditioned (immobilized and packaged) high-level waste from the reprocessing of spent nuclear fuel and, although much of the material presented here is based on information concerning high-level waste from reprocessing LWR fuel, the principles, as well as many of the details involved, are applicable to all fuel types. The report provides illustrative background material on the arising and characteristics of high-level wastes and, qualitatively, their requirements for conditioning. The report introduces the principles important in conditioned high-level waste storage and describes the types of equipment and facilities, used or studied, for handling and storage of such waste. Finally, it discusses the safety and economic aspects that are considered in the design and operation of handling and storage facilities

  19. Handling and storage of conditioned high-level wastes

    International Nuclear Information System (INIS)

    Heafield, W.

    1984-01-01

    This paper deals with certain aspects of the management of one of the most important radioactive wastes arising from the nuclear fuel cycle, i.e. the handling and storage of conditioned high-level wastes. The paper is based on an IAEA report of the same title published during 1983 in the Technical Reports Series. The paper provides illustrative background material on the characteristics of high-level wastes and, qualitatively, their requirements for conditioning. The principles important in the storage of high-level wastes are reviewed in conjunction with the radiological and socio-political considerations involved. Four fundamentally different storage concepts are described with reference to published information and the safety aspects of particular storage concepts are discussed. Finally, overall conclusions are presented which confirm the availability of technology for constructing and operating conditioned high-level waste storage facilities for periods of at least several decades. (author)

  20. Manganese-Catalyzed C−H Functionalizations: Hydroarylations and Alkenylations Involving an Unexpected Heteroaryl Shift

    KAUST Repository

    Wang, Chengming

    2017-06-24

    A manganese-catalyzed regio- and stereoselective hydroarylation of allenes is reported. The C−H functionalization method provides access to various alkenylated indoles in excellent yields. Moreover, a hydroarylation/cyclization cascade involving an unexpected C−N bond cleavage and aryl shift has been developed, which provides a new synthetic approach to substituted pyrroloindolones.

  1. Manganese-Catalyzed C−H Functionalizations: Hydroarylations and Alkenylations Involving an Unexpected Heteroaryl Shift

    KAUST Repository

    Wang, Chengming; Wang, Ai; Rueping, Magnus

    2017-01-01

    A manganese-catalyzed regio- and stereoselective hydroarylation of allenes is reported. The C−H functionalization method provides access to various alkenylated indoles in excellent yields. Moreover, a hydroarylation/cyclization cascade involving an unexpected C−N bond cleavage and aryl shift has been developed, which provides a new synthetic approach to substituted pyrroloindolones.

  2. The ATLAS High-Level Calorimeter Trigger in Run-2

    CERN Document Server

    Wiglesworth, Craig; The ATLAS collaboration

    2018-01-01

    The ATLAS Experiment uses a two-level triggering system to identify and record collision events containing a wide variety of physics signatures. It reduces the event rate from the bunch-crossing rate of 40 MHz to an average recording rate of 1 kHz, whilst maintaining high efficiency for interesting collision events. It is composed of an initial hardware-based level-1 trigger followed by a software-based high-level trigger. A central component of the high-level trigger is the calorimeter trigger. This is responsible for processing data from the electromagnetic and hadronic calorimeters in order to identify electrons, photons, taus, jets and missing transverse energy. In this talk I will present the performance of the high-level calorimeter trigger in Run-2, noting the improvements that have been made in response to the challenges of operating at high luminosity.

  3. The unexpected product of Diels-Alder reaction between "indanocyclon" and maleimide

    Science.gov (United States)

    Dobrowolski, Michał A.; Roszkowski, Piotr; Struga, Marta; Szulczyk, Daniel

    2017-02-01

    A heterocyclic compound commonly known as "indanocyclon" undergoes an unexpected Diels-Alder addition with maleimide. The resulting product has been isolated and characterized in order to get an information about its structure and possible mechanism of the reaction. Extensive comparison of single crystal properties of 3-(2,8-dioxo-1,3-diphenyl-2,8-dihydrocyclopenta[a]inden-8a(1H)-yl)pyrrolidine-2,5-dione and favorable product of the reaction has been also performed.

  4. Unexpectedly slow decrease of Chernobyl-derived radiocesium in air and deposition in Bavaria/Germany

    International Nuclear Information System (INIS)

    Bunzl, K.; Hoetzl, H.; Rosner, G.; Winkler, R.

    1995-01-01

    In this paper we analyze the corresponding data observed after the termination of the fresh fallout of Chernobyl-derived 137 Cs, and discuss possible reasons for the unexpectedly slow decrease of radiocesium in the air and in the total deposition to the ground. (SR)

  5. Unexpectedly slow decrease of Chernobyl-derived radiocesium in air and deposition in Bavaria/Germany

    Energy Technology Data Exchange (ETDEWEB)

    Bunzl, K. [GSF-Forschungszentrum fuer Umwelt und Gesundheit, Neuherberg (Germany); Hoetzl, H. [GSF-Forschungszentrum fuer Umwelt und Gesundheit, Neuherberg (Germany); Rosner, G. [Inst. fuer Strahlenschutz, Oberschleissheim (Germany); Winkler, R. [Inst. fuer Strahlenschutz, Oberschleissheim (Germany)

    1995-09-01

    In this paper we analyze the corresponding data observed after the termination of the fresh fallout of Chernobyl-derived {sup 137}Cs, and discuss possible reasons for the unexpectedly slow decrease of radiocesium in the air and in the total deposition to the ground. (SR)

  6. Coping with unexpected oil demand movements

    International Nuclear Information System (INIS)

    Anon.

    2004-01-01

    Continuous upward revisions to world oil demand projections for 2003 and 2004 are compared with the downward revisions that took place in 1998 and 1999, following the 1997 Asian economic crisis. Demand leads supply, in the current case, resulting in a time-lag in the whole supply chain, while supply led demand half a decade ago, with the OECD's commercial stocks reaching record highs. Recent months have seen a reversal of the longstanding inverse relationship between the United States of America's commercial crude oil stock levels and crude prices, and they are now moving in parallel. The fact that the US market is now adequately or even well supplied means that factors other than inventory levels are causing the present high prices. These factors are briefly outlined. OPEC is doing everything it can to maintain market stability, with prices at levels acceptable to producers and consumers. The agreement reached in Beirut on 3 June is the latest example of this. (Author)

  7. Unexpected Type of Failure of Thermal Battery Resulting in a Near Miss to a Serious Injury

    Energy Technology Data Exchange (ETDEWEB)

    Richter, Daena Kei [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-10-01

    On 6/26/2015 at 1445 in 894/136, a thermal battery (approximately the size of a commercial size C cell) experienced an unexpected failure following a routine test where the battery is activated. The failure occurred while a test operator was transferring the battery from the testing primary containment box to another containment box within the same room; initial indications are that the battery package ruptured after it went into thermal runaway which led to the operator receiving bruising to the palm of the hand from the pressure of the expulsion. The operator was wearing the prescribed PPE, which was safety glasses and a high temperature glove on the hand that was holding the battery.

  8. High-Level Waste System Process Interface Description

    International Nuclear Information System (INIS)

    D'Entremont, P.D.

    1999-01-01

    The High-Level Waste System is a set of six different processes interconnected by pipelines. These processes function as one large treatment plant that receives, stores, and treats high-level wastes from various generators at SRS and converts them into forms suitable for final disposal. The three major forms are borosilicate glass, which will be eventually disposed of in a Federal Repository, Saltstone to be buried on site, and treated water effluent that is released to the environment

  9. Unexpected persistence of extended-spectrum β-lactamase-producing Enterobacteriaceae in the faecal microbiota of hospitalised patients treated with imipenem.

    Science.gov (United States)

    Grall, N; Lazarevic, V; Gaïa, N; Couffignal, C; Laouénan, C; Ilic-Habensus, E; Wieder, I; Plesiat, P; Angebault, C; Bougnoux, M E; Armand-Lefevre, L; Andremont, A; Duval, X; Schrenzel, J

    2017-07-01

    Imipenem is active against extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) but favours the intestinal emergence of resistance. The effects of imipenem on intestinal microbiota have been studied using culture-based techniques. In this study, the effects were investigated in patients using culture and metagenomic techniques. Seventeen hospitalised adults receiving imipenem were included in a multicentre study (NCT01703299, http://www.clinicaltrials.gov). Most patients had a history of antibiotic use and/or hospitalisation. Stools were collected before, during and after imipenem treatment. Bacterial and fungal colonisation was assessed by culture, and microbiota changes were assessed using metagenomics. Unexpectedly, high colonisation rates by imipenem-susceptible ESBL-E before treatment (70.6%) remained stable over time, suggesting that imipenem intestinal concentrations were very low. Carriage rates of carbapenem-resistant Gram-negative bacilli (0-25.0%) were also stable over time, whereas those of yeasts (64.7% before treatment) peaked at 76.5% during treatment and decreased thereafter. However, these trends were not statistically significant. Yeasts included highly diverse colonising Candida spp. Metagenomics showed no global effect of imipenem on the bacterial taxonomic profiles at the sequencing depth used but demonstrated specific changes in the microbiota not detected with culture, attributed to factors other than imipenem, including sampling site or treatment with other antibiotics. In conclusion, culture and metagenomics were highly complementary in characterising the faecal microbiota of patients. The changes observed during imipenem treatment were unexpectedly limited, possibly because the microbiota was already disturbed by previous antibiotic exposure or hospitalisation. Copyright © 2017 Elsevier B.V. and International Society of Chemotherapy. All rights reserved.

  10. High-Level Waste Vitrification Facility Feasibility Study

    Energy Technology Data Exchange (ETDEWEB)

    D. A. Lopez

    1999-08-01

    A ''Settlement Agreement'' between the Department of Energy and the State of Idaho mandates that all radioactive high-level waste now stored at the Idaho Nuclear Technology and Engineering Center will be treated so that it is ready to be moved out of Idaho for disposal by a compliance date of 2035. This report investigates vitrification treatment of the high-level waste in a High-Level Waste Vitrification Facility based on the assumption that no more New Waste Calcining Facility campaigns will be conducted after June 2000. Under this option, the sodium-bearing waste remaining in the Idaho Nuclear Technology and Engineering Center Tank Farm, and newly generated liquid waste produced between now and the start of 2013, will be processed using a different option, such as a Cesium Ion Exchange Facility. The cesium-saturated waste from this other option will be sent to the Calcine Solids Storage Facilities to be mixed with existing calcine. The calcine and cesium-saturated waste will be processed in the High-Level Waste Vitrification Facility by the end of calendar year 2035. In addition, the High-Level Waste Vitrification Facility will process all newly-generated liquid waste produced between 2013 and the end of 2035. Vitrification of this waste is an acceptable treatment method for complying with the Settlement Agreement. This method involves vitrifying the waste and pouring it into stainless-steel canisters that will be ready for shipment out of Idaho to a disposal facility by 2035. These canisters will be stored at the Idaho National Engineering and Environmental Laboratory until they are sent to a national geologic repository. The operating period for vitrification treatment will be from the end of 2015 through 2035.

  11. High-Level Waste Vitrification Facility Feasibility Study

    International Nuclear Information System (INIS)

    D. A. Lopez

    1999-01-01

    A ''Settlement Agreement'' between the Department of Energy and the State of Idaho mandates that all radioactive high-level waste now stored at the Idaho Nuclear Technology and Engineering Center will be treated so that it is ready to be moved out of Idaho for disposal by a compliance date of 2035. This report investigates vitrification treatment of the high-level waste in a High-Level Waste Vitrification Facility based on the assumption that no more New Waste Calcining Facility campaigns will be conducted after June 2000. Under this option, the sodium-bearing waste remaining in the Idaho Nuclear Technology and Engineering Center Tank Farm, and newly generated liquid waste produced between now and the start of 2013, will be processed using a different option, such as a Cesium Ion Exchange Facility. The cesium-saturated waste from this other option will be sent to the Calcine Solids Storage Facilities to be mixed with existing calcine. The calcine and cesium-saturated waste will be processed in the High-Level Waste Vitrification Facility by the end of calendar year 2035. In addition, the High-Level Waste Vitrification Facility will process all newly-generated liquid waste produced between 2013 and the end of 2035. Vitrification of this waste is an acceptable treatment method for complying with the Settlement Agreement. This method involves vitrifying the waste and pouring it into stainless-steel canisters that will be ready for shipment out of Idaho to a disposal facility by 2035. These canisters will be stored at the Idaho National Engineering and Environmental Laboratory until they are sent to a national geologic repository. The operating period for vitrification treatment will be from the end of 2015 through 2035

  12. Unexpected magnetism in low dimensional systems: the role of symmetry

    International Nuclear Information System (INIS)

    Munoz, MC; Chico, L; Lopez-Sancho, MP; Beltran, JI; Gallego, S; Cerda, J

    2006-01-01

    The symmetry underlying the geometric structure of materials determines most of their physical properties. In low dimensional systems the role of symmetry is enhanced and can give rise to new phenomena. Here, we report on unexpected magnetism in carbon nanotubes and O-rich surfaces of ionic oxides, to show how its existence is closely related to the symmetry conditions. First, based on tight-binding models, we demonstrate that chiral carbon nanotubes present spin splitting at the Fermi level in the absence of a magneticfield, whereas achiral tubes preserve spin degeneracy. These remarkably different behaviors of chiral and non-chiral nanotubes are due to the intrinsic symmetry dependence of the spin-orbit interaction. Second, the occurrence of spin-polarization at ZrO 2 , Al 2 O 3 and MgO surfaces is proved by means of abinitio calculations within the density functional theory. Large spin moments develop at O-ended polar terminations, transforming the non-magnetic insulator into a half-metal. The magnetic moments mainly reside in the surface oxygen atoms, and their origin is related to the existence of 2p holes of well-defined spin polarization at the valence band of the ionic oxide. The direct relation between magnetization and local loss of donor charge shows that at the origin of these phenomena is the reduced surface symmetry

  13. High level nuclear wastes

    International Nuclear Information System (INIS)

    Lopez Perez, B.

    1987-01-01

    The transformations involved in the nuclear fuels during the burn-up at the power nuclear reactors for burn-up levels of 33.000 MWd/th are considered. Graphs and data on the radioactivity variation with the cooling time and heat power of the irradiated fuel are presented. Likewise, the cycle of the fuel in light water reactors is presented and the alternatives for the nuclear waste management are discussed. A brief description of the management of the spent fuel as a high level nuclear waste is shown, explaining the reprocessing and giving data about the fission products and their radioactivities, which must be considered on the vitrification processes. On the final storage of the nuclear waste into depth geological burials, both alternatives are coincident. The countries supporting the reprocessing are indicated and the Spanish programm defined in the Plan Energetico Nacional (PEN) is shortly reviewed. (author) 8 figs., 4 tabs

  14. High spin levels in 151Ho

    International Nuclear Information System (INIS)

    Gizon, J.; Gizon, A.; Andre, S.; Genevey, J.; Jastrzebski, J.; Kossakowski, R.; Moszinski, M.; Preibisz, Z.

    1981-02-01

    We report here on the first study of the level structure of 151 Ho. High spin levels in 151 Ho have been populated in the 141 Pr + 16 O and 144 Sm + 12 C reactions. The level structure has been established up to 6.6 MeV energy and the spins and particles determined up to 49/2 - . Most of the proposed level configurations can be explained by the coupling of hsub(11/2) protons to fsub(7/2) and/or hsub(9/2) neutrons. An isomer with 14 +- 3 ns half-life and a delayed gamma multiplicity equal to 17 +- 2 has been found. Its spin is larger than 57/2 h units

  15. Radiation transport in high-level waste form

    International Nuclear Information System (INIS)

    Arakali, V.S.; Barnes, S.M.

    1992-01-01

    The waste form selected for vitrifying high-level nuclear waste stored in underground tanks at West Valley, NY is borosilicate glass. The maximum radiation level at the surface of a canister filled with the high-level waste form is prescribed by repository design criteria for handling and disposition of the vitrified waste. This paper presents an evaluation of the radiation transport characteristics for the vitreous waste form expected to be produced at West Valley and the resulting neutron and gamma dose rates. The maximum gamma and neutron dose rates are estimated to be less than 7500 R/h and 10 mRem/h respectively at the surface of a West Valley canister filled with borosilicate waste glass

  16. Unexpected radionuclide uptake due to calcification in muscles

    International Nuclear Information System (INIS)

    Khier, A.

    1999-01-01

    Full text: A male patient aged 27 years was injected with 1000 MBq of 99 Tc m -MDP. The patient was an active man indulging in contact sport. He presented with lower back and pelvic pain. Spot pictures were made of the pelvis, lumbar spine and femurs. Unexpected active radionuclide uptake in the muscles was seen. In the delayed static images, there was focal accumulation of tracer uptake in the muscles overlying the mid-shaft of the left femur consistent with myositis ossificans. Myositis ossificans is a benign ossifying process that is generally solitary and well circumscribed. It is most commonly found in the muscles but it may occur in other connective tissues, especially tendons and subcutaneous fat. This was presumably associated with chronic muscular injuries contracted during sports activity

  17. Unexpected findings at imaging: Predicting frequency in various types of studies

    International Nuclear Information System (INIS)

    Lumbreras, Blanca; Gonzalez-Alvarez, Isabel; Lorente, Ma Fernanda; Calbo, Jorge; Aranaz, Jesus; Hernandez-Aguado, Ildefonso

    2010-01-01

    Objective: The objective was to evaluate the prevalence and associated variables of unsuspected findings from imaging tests in clinical practice. Material and Methods: Cross-sectional study of patients referred for an imaging test in 2006. Two independent radiologists classified the imaging tests according to the presence or absence of an unexpected finding in relation with the causes that prompted the test (kappa = 0.95). A thorough chart review of these patients was carried out as a quality control. Results: Out of 3259 patients in the study, 488 revealed unsuspected findings (15.0%). The prevalence of abnormal findings varied according to age: from 20.4% (150/734) in the over 74-group to 9.0% (76/847) in the under 43-group. The largest prevalence was in the category of infectious diseases (14/49, 28.6%) and in CT (260/901, 28.9%) and ultrasound (138/668, 20.7%). Studies showing moderate clinical information on the referral form were less likely to show unexpected findings than those with null or minor information (OR 0.51; 95% CI 0.36-0.73). Conclusion: Clinicians should expect the frequency of diseases detectable by imaging to increase in the future. Further research with follow-up of these findings is needed to estimate the effect of imaging technologies on final health outcomes.

  18. Unexpected findings at imaging: Predicting frequency in various types of studies

    Energy Technology Data Exchange (ETDEWEB)

    Lumbreras, Blanca [Public Health Department, Miguel Hernandez University (Spain); CIBER en Epidemiologia y Salud Publica (Spain)], E-mail: blumbreras@umh.es; Gonzalez-Alvarez, Isabel [Radiodiagnostic Department, San Juan Hospital, 03550 Alicante (Spain)], E-mail: gonzalez_isa@gva.es; Lorente, Ma Fernanda [Radiodiagnostic Department, San Juan Hospital, 03550 Alicante (Spain)], E-mail: MARFERLORENTE@telefonica.net; Calbo, Jorge [Radiodiagnostic Department, San Juan Hospital, 03550 Alicante (Spain)], E-mail: jocalma@hotmail.com; Aranaz, Jesus [Preventive Medicine Department, San Juan Hospital, 03550 Alicante (Spain)], E-mail: aranaz_jes@gva.es; Hernandez-Aguado, Ildefonso [Public Health Department, Miguel Hernandez University (Spain); CIBER en Epidemiologia y Salud Publica (Spain)], E-mail: ihernandez@umh.es

    2010-04-15

    Objective: The objective was to evaluate the prevalence and associated variables of unsuspected findings from imaging tests in clinical practice. Material and Methods: Cross-sectional study of patients referred for an imaging test in 2006. Two independent radiologists classified the imaging tests according to the presence or absence of an unexpected finding in relation with the causes that prompted the test (kappa = 0.95). A thorough chart review of these patients was carried out as a quality control. Results: Out of 3259 patients in the study, 488 revealed unsuspected findings (15.0%). The prevalence of abnormal findings varied according to age: from 20.4% (150/734) in the over 74-group to 9.0% (76/847) in the under 43-group. The largest prevalence was in the category of infectious diseases (14/49, 28.6%) and in CT (260/901, 28.9%) and ultrasound (138/668, 20.7%). Studies showing moderate clinical information on the referral form were less likely to show unexpected findings than those with null or minor information (OR 0.51; 95% CI 0.36-0.73). Conclusion: Clinicians should expect the frequency of diseases detectable by imaging to increase in the future. Further research with follow-up of these findings is needed to estimate the effect of imaging technologies on final health outcomes.

  19. Ombud's Corner: unexpected turn in the conversation?

    CERN Multimedia

    Sudeshna Datta-Cockerill

    2014-01-01

    Regular informal conversations with colleagues play a very important part in weaving the fabric of team spirit. They allow us to build the working relationships that are vital to the success of our projects and to create an environment of good will that is instrumental in averting potential conflict or crises. However, sometimes they can come with unexpected surprises…   Eric and his colleagues always meet on Monday mornings to have coffee together, before starting the working week. This is a very privileged moment for the team when there are no formal barriers or professional concerns: Mary may talk about a film that she saw at the weekend, Eric often goes hiking in the Jura with his friend Stefan, Hans has always got a story about his son’s prowess on the school football team and occasionally there is a bit of special news such as Louisa’s recent marriage, Pierre’s baby’s christening or Claude’s daughter’s graduation&...

  20. Rural families' interpretations of experiencing unexpected transition in the wake of a natural disaster.

    Science.gov (United States)

    Fernandes, Gisele Cristina Manfrini; Boehs, Astrid Eggert; Denham, Sharon A; Nitschke, Rosane Gonçalves; Martini, Jussara Gue

    2017-02-13

    Natural disasters affect populations in various parts of the world. The impacts of disasters can cause many problems to the health of people and disruption to family life, potentially leading to an unexpected transition. The objective of this paper is to present the unexpected transitional experiences of rural families following a natural disaster. A multiple case study of six families was conducted with children and adolescents in a rural area affected by a 2008 disaster in southern Brazil. For data collection, we used participant observation, narrative interviews, genograms, ecomaps and an instrument called calendar routine. The analysis of the data resulted in different family interpretations about the changes resulting from the storm and compared life before and after the disaster. The loss of homes and loved ones, migration, unemployment, and losses from the farm were the main changes associated with new development tasks. The experiences of family transition after the disaster revealed that losses influenced social lives, daily routines and the preservation of cultural values.

  1. The ALICE Dimuon Spectrometer High Level Trigger

    CERN Document Server

    Becker, B; Cicalo, Corrado; Das, Indranil; de Vaux, Gareth; Fearick, Roger; Lindenstruth, Volker; Marras, Davide; Sanyal, Abhijit; Siddhanta, Sabyasachi; Staley, Florent; Steinbeck, Timm; Szostak, Artur; Usai, Gianluca; Vilakazi, Zeblon

    2009-01-01

    The ALICE Dimuon Spectrometer High Level Trigger (dHLT) is an on-line processing stage whose primary function is to select interesting events that contain distinct physics signals from heavy resonance decays such as J/psi and Gamma particles, amidst unwanted background events. It forms part of the High Level Trigger of the ALICE experiment, whose goal is to reduce the large data rate of about 25 GB/s from the ALICE detectors by an order of magnitude, without loosing interesting physics events. The dHLT has been implemented as a software trigger within a high performance and fault tolerant data transportation framework, which is run on a large cluster of commodity compute nodes. To reach the required processing speeds, the system is built as a concurrent system with a hierarchy of processing steps. The main algorithms perform partial event reconstruction, starting with hit reconstruction on the level of the raw data received from the spectrometer. Then a tracking algorithm finds track candidates from the recon...

  2. Current high-level waste solidification technology

    International Nuclear Information System (INIS)

    Bonner, W.F.; Ross, W.A.

    1976-01-01

    Technology has been developed in the U.S. and abroad for solidification of high-level waste from nuclear power production. Several processes have been demonstrated with actual radioactive waste and are now being prepared for use in the commercial nuclear industry. Conversion of the waste to a glass form is favored because of its high degree of nondispersibility and safety

  3. The CMS High-Level Trigger

    International Nuclear Information System (INIS)

    Covarelli, R.

    2009-01-01

    At the startup of the LHC, the CMS data acquisition is expected to be able to sustain an event readout rate of up to 100 kHz from the Level-1 trigger. These events will be read into a large processor farm which will run the 'High-Level Trigger'(HLT) selection algorithms and will output a rate of about 150 Hz for permanent data storage. In this report HLT performances are shown for selections based on muons, electrons, photons, jets, missing transverse energy, τ leptons and b quarks: expected efficiencies, background rates and CPU time consumption are reported as well as relaxation criteria foreseen for a LHC startup instantaneous luminosity.

  4. The CMS High-Level Trigger

    CERN Document Server

    Covarelli, Roberto

    2009-01-01

    At the startup of the LHC, the CMS data acquisition is expected to be able to sustain an event readout rate of up to 100 kHz from the Level-1 trigger. These events will be read into a large processor farm which will run the "High-Level Trigger" (HLT) selection algorithms and will output a rate of about 150 Hz for permanent data storage. In this report HLT performances are shown for selections based on muons, electrons, photons, jets, missing transverse energy, tau leptons and b quarks: expected efficiencies, background rates and CPU time consumption are reported as well as relaxation criteria foreseen for a LHC startup instantaneous luminosity.

  5. The CMS High-Level Trigger

    Science.gov (United States)

    Covarelli, R.

    2009-12-01

    At the startup of the LHC, the CMS data acquisition is expected to be able to sustain an event readout rate of up to 100 kHz from the Level-1 trigger. These events will be read into a large processor farm which will run the "High-Level Trigger" (HLT) selection algorithms and will output a rate of about 150 Hz for permanent data storage. In this report HLT performances are shown for selections based on muons, electrons, photons, jets, missing transverse energy, τ leptons and b quarks: expected efficiencies, background rates and CPU time consumption are reported as well as relaxation criteria foreseen for a LHC startup instantaneous luminosity.

  6. SIGWX Charts - High Level Significant Weather

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — High level significant weather (SIGWX) forecasts are provided for the en-route portion of international flights. NOAA's National Weather Service Aviation Center...

  7. Ramifications of defining high-level waste

    International Nuclear Information System (INIS)

    Wood, D.E.; Campbell, M.H.; Shupe, M.W.

    1987-01-01

    The Nuclear Regulatory Commission (NRC) is considering rule making to provide a concentration-based definition of high-level waste (HLW) under authority derived from the Nuclear Waste Policy Act (NWPA) of 1982 and the Low Level Waste Policy Amendments Act of 1985. The Department of Energy (DOE), which has the responsibility to dispose of certain kinds of commercial waste, is supporting development of a risk-based classification system by the Oak Ridge National Laboratory to assist in developing and implementing the NRC rule. The system is two dimensional, with the axes based on the phrases highly radioactive and requires permanent isolation in the definition of HLW in the NWPA. Defining HLW will reduce the ambiguity in the present source-based definition by providing concentration limits to establish which materials are to be called HLW. The system allows the possibility of greater-confinement disposal for some wastes which do not require the degree of isolation provided by a repository. The definition of HLW will provide a firm basis for waste processing options which involve partitioning of waste into a high-activity stream for repository disposal, and a low-activity stream for disposal elsewhere. Several possible classification systems have been derived and the characteristics of each are discussed. The Defense High Level Waste Technology Lead Office at DOE - Richland Operations Office, supported by Rockwell Hanford Operations, has coordinated reviews of the ORNL work by a technical peer review group and other DOE offices. The reviews produced several recommendations and identified several issues to be addressed in the NRC rule making. 10 references, 3 figures

  8. An unexpected cause of diffuse alveolar hemorrhage in a kidney transplant patient.

    Science.gov (United States)

    Schlageter, Manuel; Jahn, Kathleen D; Tzankov, Alexandar; Wiese, Mark; Bubendorf, Lukas; Tamm, Michael; Savic, Spasenija

    2014-01-01

    Diffuse alveolar hemorrhage (DAH) is a life-threatening condition requiring urgent treatment. There are many different treatment-relevant causes of DAH, making the diagnostic approach to these patients complex and necessitating a multidisciplinary team. We report the case of a kidney transplant recipient in whom all diagnostic efforts did not reveal the cause of DAH, and only autopsy was able to establish an unexpected diagnosis. © 2014 S. Karger AG, Basel.

  9. 75 FR 67013 - Unexpected Urgent Refugee and Migration Needs Resulting from Violence in Kyrgyzstan

    Science.gov (United States)

    2010-11-01

    ... August 26, 2010 Unexpected Urgent Refugee and Migration Needs Resulting from Violence in Kyrgyzstan... laws of the United States, including section 2(c)(1) of the Migration and Refugee Assistance Act of... amount not to exceed $9.5 million from the United States Emergency Refugee and Migration Assistance Fund...

  10. Differences in investigations of sudden unexpected deaths in young people in a nationwide setting

    DEFF Research Database (Denmark)

    Winkel, Bo Gregers; Holst, Anders Gaarsdal; Theilade, Juliane

    2012-01-01

    BACKGROUND: Inherited disease may be causative in many young sudden unexpected death cases. Autopsy is essential in the counselling of the bereaved, as the family of the victim may be at risk too. In a nationwide setting operating under the same set of laws, we hypothesized that regional differen...

  11. Production and properties of solidified high-level waste

    International Nuclear Information System (INIS)

    Brodersen, K.

    1980-08-01

    Available information on production and properties of solidified high-level waste are presented. The review includes literature up to the end of 1979. The feasibility of production of various types of solidified high-level wast is investigated. The main emphasis is on borosilicate glass but other options are also mentioned. The expected long-term behaviour of the materials are discussed on the basis of available results from laboratory experiments. Examples of the use of the information in safety analysis of disposal in salt formations are given. The work has been made on behalf of the Danish utilities investigation of the possibilities of disposal of high-level waste in salt domes in Jutland. (author)

  12. Unexpected inhibition of CO2 gas hydrate formation in dilute TBAB solutions and the critical role of interfacial water structure

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, Ngoc N.; Nguyen, Anh V.; Nguyen, Khoi T.; Rintoul, Llew; Dang, Liem X.

    2016-12-01

    Gas hydrates formed under moderated conditions open up novel approaches to tackling issues related to energy supply, gas separation, and CO2 sequestration. Several additives like tetra-n-butylammonium bromide (TBAB) have been empirically developed and used to promote gas hydrate formation. Here we report unexpected experimental results which show that TBAB inhibits CO2 gas hydrate formation when used at minuscule concentration. We also used spectroscopic techniques and molecular dynamics simulation to gain further insights and explain the experimental results. They have revealed the critical role of water alignment at the gas-water interface induced by surface adsorption of tetra-n-butylammonium cation (TBA+) which gives rise to the unexpected inhibition of dilute TBAB solution. The water perturbation by TBA+ in the bulk is attributed to the promotion effect of high TBAB concentration on gas hydrate formation. We explain our finding using the concept of activation energy of gas hydrate formation. Our results provide a step toward to mastering the control of gas hydrate formation.

  13. 75 FR 34617 - Unexpected Urgent Refugee and Migration Needs Related to Somalia and Food Pipeline Breaks for...

    Science.gov (United States)

    2010-06-18

    ... unexpected and urgent refugee and migration needs, including by contributions to international, governmental, and nongovernmental organizations and payment of administrative expenses of the Bureau of Population...

  14. Translation of a High-Level Temporal Model into Lower Level Models: Impact of Modelling at Different Description Levels

    DEFF Research Database (Denmark)

    Kraft, Peter; Sørensen, Jens Otto

    2001-01-01

    given types of properties, and examine how descriptions on higher levels translate into descriptions on lower levels. Our example looks at temporal properties where the information is concerned with the existence in time. In a high level temporal model with information kept in a three-dimensional space...... the existences in time can be mapped precisely and consistently securing a consistent handling of the temporal properties. We translate the high level temporal model into an entity-relationship model, with the information in a two-dimensional graph, and finally we look at the translations into relational...... and other textual models. We also consider the aptness of models that include procedural mechanisms such as active and object databases...

  15. Evaluation of radionuclide concentrations in high-level radioactive wastes

    International Nuclear Information System (INIS)

    Fehringer, D.J.

    1985-10-01

    This report describes a possible approach for development of a numerical definition of the term ''high-level radioactive waste.'' Five wastes are identified which are recognized as being high-level wastes under current, non-numerical definitions. The constituents of these wastes are examined and the most hazardous component radionuclides are identified. This report suggests that other wastes with similar concentrations of these radionuclides could also be defined as high-level wastes. 15 refs., 9 figs., 4 tabs

  16. Timing of High-level Waste Disposal

    International Nuclear Information System (INIS)

    2008-01-01

    This study identifies key factors influencing the timing of high-level waste (HLW) disposal and examines how social acceptability, technical soundness, environmental responsibility and economic feasibility impact on national strategies for HLW management and disposal. Based on case study analyses, it also presents the strategic approaches adopted in a number of national policies to address public concerns and civil society requirements regarding long-term stewardship of high-level radioactive waste. The findings and conclusions of the study confirm the importance of informing all stakeholders and involving them in the decision-making process in order to implement HLW disposal strategies successfully. This study will be of considerable interest to nuclear energy policy makers and analysts as well as to experts in the area of radioactive waste management and disposal. (author)

  17. High-Level Waste Melter Study Report

    Energy Technology Data Exchange (ETDEWEB)

    Perez, Joseph M.; Bickford, Dennis F.; Day, Delbert E.; Kim, Dong-Sang; Lambert, Steven L.; Marra, Sharon L.; Peeler, David K.; Strachan, Denis M.; Triplett, Mark B.; Vienna, John D.; Wittman, Richard S.

    2001-07-13

    At the Hanford Site in Richland, Washington, the path to site cleanup involves vitrification of the majority of the wastes that currently reside in large underground tanks. A Joule-heated glass melter is the equipment of choice for vitrifying the high-level fraction of these wastes. Even though this technology has general national and international acceptance, opportunities may exist to improve or change the technology to reduce the enormous cost of accomplishing the mission of site cleanup. Consequently, the U.S. Department of Energy requested the staff of the Tanks Focus Area to review immobilization technologies, waste forms, and modifications to requirements for solidification of the high-level waste fraction at Hanford to determine what aspects could affect cost reductions with reasonable long-term risk. The results of this study are summarized in this report.

  18. [Algorithm for securing an unexpected difficult airway : User analysis on a simulator].

    Science.gov (United States)

    Ott, T; Truschinski, K; Kriege, M; Naß, M; Herrmann, S; Ott, V; Sellin, S

    2018-01-01

     laryngeal mask in 22% and other instruments in 39%. Of the 50 participants 38 had already been institutionally trained in difficult airway management during the previous 2 years. For cricothyrotomy the participants needed a median time of 63 s and there was no difference between junior and senior anesthetists (p = 0.46). The cricothyrotomy was performed faster using a surgical approach than a transtracheal puncture approach using a Melker emergency cricothyrotomy set (52 s vs. 73 s, p = 0.014). The conformity to the algorithm of over 90% indicates a good training level of the participants concerning the difficult airway algorithm. In the observed sample flexible intubation endoscopy tended to be of high significance even in the unanticipated difficult airway. Cricothyrotomy was performed faster surgically than by the use of the transtracheal puncture approach, while no differences between junior and senior anesthetists were observed. For the successful management of an unexpected difficult airway, specific training of these special and rare events is crucial. A standardized provision of special airway instruments stored in a special trolley and frequent application of this trolley in the clinical routine is recommended.

  19. Nuclear fission - the unexpected discovery seventy years ago

    International Nuclear Information System (INIS)

    Weis, Michael

    2008-01-01

    Seventy years ago, on December 17, 1938, Otto Hahn, Lise Meitner, and Fritz Strassmann discovered nuclear fission. It was a serendipitous discovery resulting from the consistent pursuit, for many years, of occasionally unexpected radiochemical experimental findings. Hardly any other scientific discovery has had such direct bearing on our life, changing our view of the world. It over-threw the tenet of physics, believed to be incontestable, that the atom was indivisible. The use of nuclear power it has made possible has given rise to immense benefits, but it has also allowed mankind's most dreadful weapon so far to be developed. All this is ample reason seventy years later to recall the discovery, the discoverers and their times. It will also be shown what later generations have made of this discovery, and what economic and ecological prospects it continues to hold. (orig.)

  20. Structures of Rotavirus Reassortants Demonstrate Correlation of Altered Conformation of the VP4 Spike and Expression of Unexpected VP4-Associated Phenotypes

    Science.gov (United States)

    Pesavento, Joseph B.; Billingsley, Angela M.; Roberts, Ed J.; Ramig, Robert F.; Prasad, B. V. Venkataram

    2003-01-01

    Numerous prior studies have indicated that viable rotavirus reassortants containing structural proteins of heterologous parental origin may express unexpected phenotypes, such as changes in infectivity and immunogenicity. To provide a structural basis for alterations in phenotypic expression, a three-dimensional structural analysis of these reassortants was conducted. The structures of the reassortants show that while VP4 generally maintains the parental structure when moved to a heterologous protein background, in certain reassortants, there are subtle alterations in the conformation of VP4. The alterations in VP4 conformation correlated with expression of unexpected VP4-associated phenotypes. Interactions between heterologous VP4 and VP7 in reassortants expressing unexpected phenotypes appeared to induce the conformational alterations seen in VP4. PMID:12584352

  1. Sunburn as a Cause of Unexpected Neutrophilia in a Healthy Pregnant Woman

    OpenAIRE

    Harper, Robert

    2018-01-01

    Background. Neutrophilia has a broad differential diagnosis and represents a systemic response to an infection or other inflammatory pathologies. Case. A 31-year-old woman, Gravida 3, Para 2 at 28 weeks of gestation, presented to the day assessment unit following routine blood tests that showed an unexpected marked neutrophilia. The underlying cause of the neutrophilia was sunburn. The sunburn recovered and her neutrophil count spontaneously normalised. Conclusion. Clinicians can add sunburn ...

  2. Dynamic Asset Allocation Strategies Based on Volatility, Unexpected Volatility and Financial Turbulence

    OpenAIRE

    Grimsrud, David Borkner

    2015-01-01

    Masteroppgave økonomi og administrasjon- Universitetet i Agder, 2015 This master thesis looks at unexpected volatility- and financial turbulence’s predictive ability, and exploit these measures of financial risk, together with volatility, to create three dynamic asset allocation strategies, and test if they can outperform a passive and naively diversified buy-and-hold strategy. The idea with the dynamic strategies is to increase the portfolio return by keeping the portfolio risk at a low a...

  3. Epilepsy and risk of death and sudden unexpected death in the young

    DEFF Research Database (Denmark)

    Holst, Anders Gaarsdal; Winkel, Bo Gregers; Risgaard, Bjarke

    2013-01-01

    Patients with epilepsy are at increased risk of premature death from all causes and likely also from sudden unexplained death (SUD). Many patients with epilepsy have significant comorbidity, and it is unclear how much of the increased risk can be explained by epilepsy itself. We aimed to chart...... the incidence of sudden unexpected death in epilepsy (SUDEP) and estimate the risk of death from all causes and SUD conferred by epilepsy independently....

  4. Prevalence of incidental or unexpected findings on low-dose CT performed during routine SPECT/CT nuclear medicine studies

    International Nuclear Information System (INIS)

    Yap, Kelvin Kwok-Ho; Sutherland, Tom; Shafik-Eid, Raymond; Taubman, Kim; Schlicht, Stephen; Ramaseshan, Ganeshan

    2015-01-01

    In nuclear medicine, single-photon-emission computed tomography (SPECT) is often combined with ‘simultaneous’ low-dose CT (LDCT) to provide complementary anatomical and functional correlation. As a consequence, numerous incidental and unexpected findings may be detected on LDCT. Recognition of these findings and appropriate determination of their relevance can add to the utility of SPECT/CT. We aimed to evaluate the prevalence and categorise the relevance of incidental and unexpected findings on LDCT scans performed as part of routine SPECT/CT studies. All available LDCT scans performed as part of SPECT/CT studies at St. Vincent's Hospital Melbourne in the year 2013 were retrospectively reviewed. Two qualified radiologists independently reviewed the studies and any previous available imaging and categorised any detected incidental findings. A total of 2447 LDCT studies were reviewed. The relevance of the findings was classified according to a modified version of a scale used in the Colonography Reporting and Data System: E1 = normal or normal variant (28.0%); E2 = clinically unimportant (63.5%); E3 = likely unimportant or incompletely characterised (6.2%); E4 = potentially important (2.5%). Imaging specialists need to be cognisant of incidental and unexpected findings present on LDCT studies performed as part of SPECT/CT. Appropriate categorisation of findings and communication of potentially important findings to referring clinicians should form part of routine practice. The overall prevalence of potentially significant incidental and unexpected findings in our series was 8.7% (E3, 6.2%; E4, 2.5%) and was comparable to rates in other published imaging series.

  5. Adaptation to sudden unexpected loading of the low back - the effects of repeated trials

    DEFF Research Database (Denmark)

    Skotte, J.H.; Fallentin, N.; Pedersen, Mogens Theisen

    2004-01-01

    The purpose of this study was to investigate short-term changes in reactions to sudden unexpected loading of the low back. The study utilized a set-up where a horizontal force of 58 N pointing forward suddenly was applied to the upper part of the subject's trunk. EMG activity from the erector...

  6. Unexpected storm-time nightside plasmaspheric density enhancement at low L shell

    Science.gov (United States)

    Chu, X.; Bortnik, J.; Denton, R. E.; Yue, C.

    2017-12-01

    We have developed a three-dimensional dynamic electron density (DEN3D) model in the inner magnetosphere using a neural network approach. The DEN3D model can provide spatiotemporal distribution of the electron density at any location and time that spacecraft observations are not available. Given DEN3D's good performance in predicting the structure and dynamic evolution of the plasma density, the salient features of the DEN3D model can be used to gain further insight into the physics. For instance, the DEN3D models can be used to find unusual phenomena that are difficult to detect in observations or simulations. We report, for the first time, an unexpected plasmaspheric density increase at low L shell regions on the nightside during the main phase of a moderate storm during 12-16 October 2004, as opposed to the expected density decrease due to storm-time plasmaspheric erosion. The unexpected density increase is first discovered in the modeled electron density distribution using the DEN3D model, and then validated using in-situ density measurements obtained from the IMAGE satellite. The density increase was likely caused by increased earthward transverse field plasma transport due to enhanced nightside ExB drift, which coincided with enhanced solar wind electric field and substorm activity. This is consistent with the results of physics-based simulation SAMI3 model which show earthward enhanced plasma transport and electron density increase at low L shells during storm main phase.

  7. Sterilization, high-level disinfection, and environmental cleaning.

    Science.gov (United States)

    Rutala, William A; Weber, David J

    2011-03-01

    Failure to perform proper disinfection and sterilization of medical devices may lead to introduction of pathogens, resulting in infection. New techniques have been developed for achieving high-level disinfection and adequate environmental cleanliness. This article examines new technologies for sterilization and high-level disinfection of critical and semicritical items, respectively, and because semicritical items carry the greatest risk of infection, the authors discuss reprocessing semicritical items such as endoscopes and automated endoscope reprocessors, endocavitary probes, prostate biopsy probes, tonometers, laryngoscopes, and infrared coagulation devices. In addition, current issues and practices associated with environmental cleaning are reviewed. Copyright © 2011. Published by Elsevier Inc.

  8. Slovnaft posts unexpectedly high profits

    International Nuclear Information System (INIS)

    Beer, G.

    2004-01-01

    For many years, Slovnaft used the movement of the price of Brent crude as an argument to explain the movement of its prices. It assumed the price of Urals crude would follow the Brent crude price after a short period. It was still using this argument in 2002. Urals crude was for a long period about 2 USD per barrel (159 l) cheaper than Brent. But over recent last months, the price difference between Brent crude and Ural crude has been increasing. According to the pricing policy, customers of Hungarian-owned MOL/Slovnaft might expect fuel prices to fall. But this did not happen. Slovnaft no longer uses Brent prices to justify its prices and focuses on the development of the FOB Rotterdam fuel market. When prices increase on the FOB Rotterdam fuel market, refineries in neighbouring regions export oil to this market. And in order to maintain stability on the market, other refineries also increase their prices. Slovnaft benefits not only from cheaper Russian oil but also from the major investments it made in the past. While other refineries use distillation residues to produce cheaper heavy heating oils, Slovnaft is able to convert such residues into fuel. And this also has an economic impact. B. Kelemen admits that it will be mainly shareholders who benefit from these developments.It is not only rising oil prices that have been noticeable recently, but also the lack of investment in the oil industry. The capacity of Russian pipelines, tankers and the processing capacity of refineries has been insufficient for some time. Whereas fuel consumption is growing year after year. Preliminary calculations indicate the oil industry needs to invest about 700 bill. USD and investors expect a return, according to B. Kelemen, of 10 to 17%. The closest competitors of Slovnaft will have to invest in desulphurization and the processing of heavy residues. And so Slovnaft can look forward to very profitable years. The same cannot be said of its customers. Slovnaft is set to publish record-breaking figures on November 12 for the first three quarters of the year. (author)

  9. The unexpected in primary care: a multicenter study on the emergence of unvoiced patient agenda.

    NARCIS (Netherlands)

    Peltenburg, M.; Fischer, J.E.; Bahrs, O.; Dulmen, S. van; Brink-Muinen, A. van den

    2004-01-01

    PURPOSE: Within the time constraints of a typical physician-patient encounter, the full patient agenda will rarely be voiced. Unexpectedly revealed issues that were neither on the patient's list of items for discussion nor anticipated by the physician constitute an emerging agenda. We aimed to

  10. A case-crossover analyses of fine particulate matter and out-of-hospital sudden unexpected death

    Science.gov (United States)

    Out-of-hospital sudden unexpected deaths (OHSUD) are natural deaths that occur without obvious underlying causes and account for nearly 1 in 6 deaths in the United States. Ambient air pollution is known to be causally related to overall mortality, therefore, we hypothesized that ...

  11. 3 CFR - Unexpected Urgent Refugee and Migration Needs Related to the Continuing Conflict in Pakistan

    Science.gov (United States)

    2010-01-01

    ... 3 The President 1 2010-01-01 2010-01-01 false Unexpected Urgent Refugee and Migration Needs Related to the Continuing Conflict in Pakistan Presidential Documents Other Presidential Documents... to the Continuing Conflict in Pakistan Memorandum for the Secretary of State By the authority vested...

  12. Unexpected Relationships and Inbreeding in HapMap Phase III Populations

    Science.gov (United States)

    Stevens, Eric L.; Baugher, Joseph D.; Shirley, Matthew D.; Frelin, Laurence P.; Pevsner, Jonathan

    2012-01-01

    Correct annotation of the genetic relationships between samples is essential for population genomic studies, which could be biased by errors or omissions. To this end, we used identity-by-state (IBS) and identity-by-descent (IBD) methods to assess genetic relatedness of individuals within HapMap phase III data. We analyzed data from 1,397 individuals across 11 ethnic populations. Our results support previous studies (Pemberton et al., 2010; Kyriazopoulou-Panagiotopoulou et al., 2011) assessing unknown relatedness present within this population. Additionally, we present evidence for 1,657 novel pairwise relationships across 9 populations. Surprisingly, significant Cotterman's coefficients of relatedness K1 (IBD1) values were detected between pairs of known parents. Furthermore, significant K2 (IBD2) values were detected in 32 previously annotated parent-child relationships. Consistent with a hypothesis of inbreeding, regions of homozygosity (ROH) were identified in the offspring of related parents, of which a subset overlapped those reported in previous studies (Gibson et al. 2010; Johnson et al. 2011). In total, we inferred 28 inbred individuals with ROH that overlapped areas of relatedness between the parents and/or IBD2 sharing at a different genomic locus between a child and a parent. Finally, 8 previously annotated parent-child relationships had unexpected K0 (IBD0) values (resulting from a chromosomal abnormality or genotype error), and 10 previously annotated second-degree relationships along with 38 other novel pairwise relationships had unexpected IBD2 (indicating two separate paths of recent ancestry). These newly described types of relatedness may impact the outcome of previous studies and should inform the design of future studies relying on the HapMap Phase III resource. PMID:23185369

  13. High level of CA 125 due to large endometrioma.

    Science.gov (United States)

    Phupong, Vorapong; Chen, Orawan; Ultchaswadi, Pornthip

    2004-09-01

    CA 125 is a tumor-associated antigen. Its high levels are usually associated with ovarian malignancies, whereas smaller increases in the levels were associated with benign gynecologic conditions. The authors report a high level of CA 125 in a case of large ovarian endometrioma. A 45-year-old nulliparous Thai woman, presented with an increase of her abdominal girth for 7 months. Transabdominal ultrasonogram demonstrated a large ovarian cyst and multiple small leiomyoma uteri, and serum CA 125 level was 1,006 U/ml. The preoperative diagnosis was ovarian cancer with leiomyoma uteri. Exploratory laparotomy was performed. There were a large right ovarian endometrioma, small left ovarian endometrioma and multiple small leiomyoma. Total abdominal hysterectomy and bilateral salpingo-oophorectomy was performed and histopathology confirmed the diagnosis of endometrioma and leiomyoma. The serum CA 125 level declined to non-detectable at the 4th week. She was well at discharge and throughout her 4th week follow-up period Although a very high level of CA 125 is associated with a malignant process, it can also be found in benign conditions such as a large endometrioma. The case emphasizes the association of high levels of CA 125 with benign gynecologic conditions.

  14. On the predictability of high water level along the US East Coast: can the Florida Current measurement be an indicator for flooding caused by remote forcing?

    Science.gov (United States)

    Ezer, Tal; Atkinson, Larry P.

    2017-06-01

    landfall can cause a weakening of the FCT and unexpected high water level and flooding along the US East Coast. A regression-prediction model based on the MDWL-FCT correlation shows some skill in estimating high water levels during past storms; the water level prediction is more accurate for slow-moving and offshore storms than it is for fast-moving storms. The study can help to improve water level prediction since current storm surge models rely on local wind but may ignore remote forcing.

  15. Unexpected findings of a female team in Xochimilco, Mexico.

    Science.gov (United States)

    Martínez-Salgado, C

    1999-01-01

    This is a reflection about the methodological circumstances that led the author to certain unexpected information during the course of a qualitative approach to the perception of health problems of a group of poor families in the south of Mexico City. Special attention is paid to the influence of the research team composition (four women with different professional backgrounds, ages, marital statuses, and styles of personal interaction) and the psychoanalytic technique that influenced the study. The inclusion of people of different ages, professions, and personality traits proved extremely valuable both as a means of widening the possibilities for empathetic relations between the research group and the population studied and for increasing the shades of meaning that the team was able to capture.

  16. Rural families' interpretations of experiencing unexpected transition in the wake of a natural disaster

    Directory of Open Access Journals (Sweden)

    Gisele Cristina Manfrini Fernandes

    Full Text Available Abstract: Natural disasters affect populations in various parts of the world. The impacts of disasters can cause many problems to the health of people and disruption to family life, potentially leading to an unexpected transition. The objective of this paper is to present the unexpected transitional experiences of rural families following a natural disaster. A multiple case study of six families was conducted with children and adolescents in a rural area affected by a 2008 disaster in southern Brazil. For data collection, we used participant observation, narrative interviews, genograms, ecomaps and an instrument called calendar routine. The analysis of the data resulted in different family interpretations about the changes resulting from the storm and compared life before and after the disaster. The loss of homes and loved ones, migration, unemployment, and losses from the farm were the main changes associated with new development tasks. The experiences of family transition after the disaster revealed that losses influenced social lives, daily routines and the preservation of cultural values.

  17. The sleep of elite athletes at sea level and high altitude: a comparison of sea-level natives and high-altitude natives (ISA3600).

    Science.gov (United States)

    Roach, Gregory D; Schmidt, Walter F; Aughey, Robert J; Bourdon, Pitre C; Soria, Rudy; Claros, Jesus C Jimenez; Garvican-Lewis, Laura A; Buchheit, Martin; Simpson, Ben M; Hammond, Kristal; Kley, Marlen; Wachsmuth, Nadine; Gore, Christopher J; Sargent, Charli

    2013-12-01

    Altitude exposure causes acute sleep disruption in non-athletes, but little is known about its effects in elite athletes. The aim of this study was to examine the effects of altitude on two groups of elite athletes, that is, sea-level natives and high-altitude natives. Sea-level natives were members of the Australian under-17 soccer team (n=14). High-altitude natives were members of a Bolivian under-20 club team (n=12). Teams participated in an 18-day (19 nights) training camp in Bolivia, with 6 nights at near sea level in Santa Cruz (430 m) and 13 nights at high altitude in La Paz (3600 m). Sleep was assessed on every day/night using activity monitors. The Australians' sleep was shorter, and of poorer quality, on the first night at altitude compared with sea level. Sleep quality returned to normal by the end of the first week at altitude, but sleep quantity had still not stabilised at its normal level after 2 weeks. The quantity and quality of sleep obtained by the Bolivians was similar, or greater, on all nights at altitude compared with sea level. The Australians tended to obtain more sleep than the Bolivians at sea level and altitude, but the quality of the Bolivians' sleep tended to be better than that of the Australians at altitude. Exposure to high altitude causes acute and chronic disruption to the sleep of elite athletes who are sea-level natives, but it does not affect the sleep of elite athletes who are high-altitude natives.

  18. The measurement for level of marine high-temperature and high-pressure vessels

    International Nuclear Information System (INIS)

    Lin Jie.

    1986-01-01

    The various error factors in measurement for level of marine high-temperature and high-pressure vessels are anslysed. The measuring method of error self compensation and its simplification for land use are shown

  19. Challenging Ideals of Reciprocity in Undergraduate Teaching: The Unexpected Benefits of Unpredictable Cross-Cultural Fieldwork

    Science.gov (United States)

    Hammersley, Laura A.; Bilous, Rebecca H.; James, Sarah W.; Trau, Adam M.; Suchet-Pearson, Sandie

    2014-01-01

    Geographers are increasingly grappling with the theoretical and practical implications of integrating an ethics of reciprocity into undergraduate learning and teaching. This paper draws on the unexpected experiences of a third-year human geography research methods fieldtrip to examine the process of balancing undergraduate student learning and…

  20. Dealing with the unexpected: consumer responses to direct-access BRCA mutation testing

    Directory of Open Access Journals (Sweden)

    Uta Francke

    2013-02-01

    Full Text Available Background. Inherited BRCA gene mutations convey a high risk for breast and ovarian cancer, but current guidelines limit BRCA mutation testing to women with early-onset cancer and relatives of mutation-positive cases. Benefits and risks of providing this information directly to consumers are unknown.Methods. To assess and quantify emotional and behavioral reactions of consumers to their 23andMe Personal Genome Service® report of three BRCA mutations that are common in Ashkenazi Jews, we invited all 136 BRCA1 and BRCA2 mutation-positive individuals in the 23andMe customer database who had chosen to view their BRCA reports to participate in this IRB-approved study. We also invited 160 mutation-negative customers who were matched for age, sex and ancestry. Semi-structured phone interviews were completed for 32 mutation carriers, 16 women and 16 men, and 31 non-carriers. Questions addressed personal and family history of cancer, decision and timing of viewing the BRCA report, recollection of the result, emotional responses, perception of personal cancer risk, information sharing, and actions taken or planned.Results. Eleven women and 14 men had received the unexpected result that they are carriers of a BRCA1 185delAG or 5382insC, or BRCA2 6174delT mutation. None of them reported extreme anxiety and four experienced moderate anxiety that was transitory. Remarkably, five women and six men described their response as neutral. Most carrier women sought medical advice and four underwent risk-reducing procedures after confirmatory mutation testing. Male carriers realized that their test results implied genetic risk for female relatives, and several of them felt considerably burdened by this fact. Sharing mutation information with family members led to screening of at least 30 relatives and identification of 13 additional carriers. Non-carriers did not report inappropriate actions, such as foregoing cancer screening. All but one of the 32 mutation

  1. Dealing with the unexpected: consumer responses to direct-access BRCA mutation testing.

    Science.gov (United States)

    Francke, Uta; Dijamco, Cheri; Kiefer, Amy K; Eriksson, Nicholas; Moiseff, Bianca; Tung, Joyce Y; Mountain, Joanna L

    2013-01-01

    Background. Inherited BRCA gene mutations convey a high risk for breast and ovarian cancer, but current guidelines limit BRCA mutation testing to women with early-onset cancer and relatives of mutation-positive cases. Benefits and risks of providing this information directly to consumers are unknown. Methods. To assess and quantify emotional and behavioral reactions of consumers to their 23andMe Personal Genome Service(®) report of three BRCA mutations that are common in Ashkenazi Jews, we invited all 136 BRCA1 and BRCA2 mutation-positive individuals in the 23andMe customer database who had chosen to view their BRCA reports to participate in this IRB-approved study. We also invited 160 mutation-negative customers who were matched for age, sex and ancestry. Semi-structured phone interviews were completed for 32 mutation carriers, 16 women and 16 men, and 31 non-carriers. Questions addressed personal and family history of cancer, decision and timing of viewing the BRCA report, recollection of the result, emotional responses, perception of personal cancer risk, information sharing, and actions taken or planned. Results. Eleven women and 14 men had received the unexpected result that they are carriers of a BRCA1 185delAG or 5382insC, or BRCA2 6174delT mutation. None of them reported extreme anxiety and four experienced moderate anxiety that was transitory. Remarkably, five women and six men described their response as neutral. Most carrier women sought medical advice and four underwent risk-reducing procedures after confirmatory mutation testing. Male carriers realized that their test results implied genetic risk for female relatives, and several of them felt considerably burdened by this fact. Sharing mutation information with family members led to screening of at least 30 relatives and identification of 13 additional carriers. Non-carriers did not report inappropriate actions, such as foregoing cancer screening. All but one of the 32 mutation-positive participants

  2. Final repositories for high-level radioactive waste; Endlagerung hochradioaktiver Abfaelle

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2015-10-15

    The brochure on final repositories for high-level radioactive waste covers the following issues: What is the origin of radioactive wastes? How large are the waste amounts? What is going to happen with the wastes? What is the solution for the Waste disposal? A new site search is started. Safety requirements for the final disposal of high-level radioactive wastes. Comparison of host rocks. Who is responsible and who will pay? Final disposal of high-level radioactive wastes worldwide. Short summary: History of the search for a final repository for high-level radioactive wastes in Germany.

  3. The high level vibration test program

    International Nuclear Information System (INIS)

    Hofmayer, C.H.; Curreri, J.R.; Park, Y.J.; Kato, W.Y.; Kawakami, S.

    1989-01-01

    As part of cooperative agreements between the US and Japan, tests have been performed on the seismic vibration table at the Tadotsu Engineering Laboratory of Nuclear Power Engineering Test Center (NUPEC) in Japan. The objective of the test program was to use the NUPEC vibration table to drive large diameter nuclear power piping to substantial plastic strain with an earthquake excitation and to compare the results with state-of-the-art analysis of the problem. The test model was subjected to a maximum acceleration well beyond what nuclear power plants are designed to withstand. A modified earthquake excitation was applied and the excitation level was increased carefully to minimize the cumulative fatigue damage due to the intermediate level excitations. Since the piping was pressurized, and the high level earthquake excitation was repeated several times, it was possible to investigate the effects of ratchetting and fatigue as well. Elastic and inelastic seismic response behavior of the test model was measured in a number of test runs with an increasing excitation input level up to the limit of the vibration table. In the maximum input condition, large dynamic plastic strains were obtained in the piping. Crack initiation was detected following the second maximum excitation run. Crack growth was carefully monitored during the next two additional maximum excitation runs. The final test resulted in a maximum crack depth of approximately 94% of the wall thickness. The HLVT (high level vibration test) program has enhanced understanding of the behavior of piping systems under severe earthquake loading. As in other tests to failure of piping components, it has demonstrated significant seismic margin in nuclear power plant piping

  4. Discovery of high-level tasks in the operating room

    NARCIS (Netherlands)

    Bouarfa, L.; Jonker, P.P.; Dankelman, J.

    2010-01-01

    Recognizing and understanding surgical high-level tasks from sensor readings is important for surgical workflow analysis. Surgical high-level task recognition is also a challenging task in ubiquitous computing because of the inherent uncertainty of sensor data and the complexity of the operating

  5. Overview of high-level waste management accomplishments

    International Nuclear Information System (INIS)

    Lawroski, H.; Berreth, J.R.; Freeby, W.A.

    1980-01-01

    Storage of power reactor spent fuel is necessary at present because of the lack of reprocessing operations particularly in the U.S. By considering the above solidification and storage scenario, there is more than reasonable assurance that acceptable, stable, low heat generation rate, solidified waste can be produced, and safely disposed. The public perception of no waste disposal solutions is being exploited by detractors of nuclear power application. The inability to even point to one overall system demonstration lends credibility to the negative assertions. By delaying the gathering of on-line information to qualify repository sites, and to implement a demonstration, the actions of the nuclear power detractors are self serving in that they can continue to point out there is no demonstration of satisfactory high-level waste disposal. By maintaining the liquid and solidified high-level waste in secure above ground storage until acceptable decay heat generation rates are achieved, by producing a compatible, high integrity, solid waste form, by providing a second or even third barrier as a compound container and by inserting the enclosed waste form in a qualified repository with spacing to assure moderately low temperature disposal conditions, there appears to be no technical reason for not progressing further with the disposal of high-level wastes and needed implementation of the complete nuclear power fuel cycle

  6. Evaluation of solidified high-level waste forms

    International Nuclear Information System (INIS)

    1981-01-01

    One of the objectives of the IAEA waste management programme is to coordinate and promote development of improved technology for the safe management of radioactive wastes. The Agency accomplished this objective specifically through sponsoring Coordinated Research Programmes on the ''Evaluation of Solidified High Level Waste Products'' in 1977. The primary objectives of this programme are to review and disseminate information on the properties of solidified high-level waste forms, to provide a mechanism for analysis and comparison of results from different institutes, and to help coordinate future plans and actions. This report is a summary compilation of the key information disseminated at the second meeting of this programme

  7. Spent fuel and high-level radioactive waste storage

    International Nuclear Information System (INIS)

    Trigerman, S.

    1988-06-01

    The subject of spent fuel and high-level radioactive waste storage, is bibliographically reviewed. The review shows that in the majority of the countries, spent fuels and high-level radioactive wastes are planned to be stored for tens of years. Sites for final disposal of high-level radioactive wastes have not yet been found. A first final disposal facility is expected to come into operation in the United States of America by the year 2010. Other final disposal facilities are expected to come into operation in Germany, Sweden, Switzerland and Japan by the year 2020. Meanwhile , stress is placed upon the 'dry storage' method which is carried out successfully in a number of countries (Britain and France). In the United States of America spent fuels are stored in water pools while the 'dry storage' method is still being investigated. (Author)

  8. Properties and characteristics of high-level waste glass

    International Nuclear Information System (INIS)

    Ross, W.A.

    1977-01-01

    This paper has briefly reviewed many of the characteristics and properties of high-level waste glasses. From this review, it can be noted that glass has many desirable properties for solidification of high-level wastes. The most important of these include: (1) its low leach rate; (2) the ability to tolerate large changes in waste composition; (3) the tolerance of anticipated storage temperatures; (4) its low surface area even after thermal shock or impact

  9. Stable superconducting magnet. [high current levels below critical temperature

    Science.gov (United States)

    Boom, R. W. (Inventor)

    1967-01-01

    Operation of a superconducting magnet is considered. A method is described for; (1) obtaining a relatively high current in a superconducting magnet positioned in a bath of a gas refrigerant; (2) operating a superconducting magnet at a relatively high current level without training; and (3) operating a superconducting magnet containing a plurality of turns of a niobium zirconium wire at a relatively high current level without training.

  10. ALICE High Level Trigger

    CERN Multimedia

    Alt, T

    2013-01-01

    The ALICE High Level Trigger (HLT) is a computing farm designed and build for the real-time, online processing of the raw data produced by the ALICE detectors. Events are fully reconstructed from the raw data, analyzed and compressed. The analysis summary together with the compressed data and a trigger decision is sent to the DAQ. In addition the reconstruction of the events allows for on-line monitoring of physical observables and this information is provided to the Data Quality Monitor (DQM). The HLT can process event rates of up to 2 kHz for proton-proton and 200 Hz for Pb-Pb central collisions.

  11. The sleep of elite athletes at sea level and high altitude: a comparison of sea-level natives and high-altitude natives (ISA3600)

    Science.gov (United States)

    Roach, Gregory D; Schmidt, Walter F; Aughey, Robert J; Bourdon, Pitre C; Soria, Rudy; Claros, Jesus C Jimenez; Garvican-Lewis, Laura A; Buchheit, Martin; Simpson, Ben M; Hammond, Kristal; Kley, Marlen; Wachsmuth, Nadine; Gore, Christopher J; Sargent, Charli

    2013-01-01

    Background Altitude exposure causes acute sleep disruption in non-athletes, but little is known about its effects in elite athletes. The aim of this study was to examine the effects of altitude on two groups of elite athletes, that is, sea-level natives and high-altitude natives. Methods Sea-level natives were members of the Australian under-17 soccer team (n=14). High-altitude natives were members of a Bolivian under-20 club team (n=12). Teams participated in an 18-day (19 nights) training camp in Bolivia, with 6 nights at near sea level in Santa Cruz (430 m) and 13 nights at high altitude in La Paz (3600 m). Sleep was assessed on every day/night using activity monitors. Results The Australians’ sleep was shorter, and of poorer quality, on the first night at altitude compared with sea level. Sleep quality returned to normal by the end of the first week at altitude, but sleep quantity had still not stabilised at its normal level after 2 weeks. The quantity and quality of sleep obtained by the Bolivians was similar, or greater, on all nights at altitude compared with sea level. The Australians tended to obtain more sleep than the Bolivians at sea level and altitude, but the quality of the Bolivians’ sleep tended to be better than that of the Australians at altitude. Conclusions Exposure to high altitude causes acute and chronic disruption to the sleep of elite athletes who are sea-level natives, but it does not affect the sleep of elite athletes who are high-altitude natives. PMID:24282197

  12. Unexpected strong magnetism of Cu doped single-layer MoS₂ and its origin.

    Science.gov (United States)

    Yun, Won Seok; Lee, J D

    2014-05-21

    The magnetism of the 3d transition-metal (TM) doped single-layer (1L) MoS2, where the Mo atom is partially replaced by the 3d TM atom, is investigated using the first-principles density functional calculations. In a series of 3d TM doped 1L-MoS2's, the induced spin polarizations are negligible for Sc, Ti, and Cr dopings, while the induced spin polarizations are confirmed for V, Mn, Fe, Co, Ni, Cu, and Zn dopings and the systems become magnetic. Especially, the Cu doped system shows unexpectedly strong magnetism although Cu is nonmagnetic in its bulk state. The driving force is found to be a strong hybridization between Cu 3d states and 3p states of neighboring S, which results in an extreme unbalanced spin-population in the spin-split impurity bands near the Fermi level. Finally, we also discuss further issues of the Cu induced magnetism of 1L-MoS2 such as investigation of additional charge states, the Cu doping at the S site instead of the Mo site, and the Cu adatom on the layer (i.e., 1L-MoS2).

  13. Analysis of Cyberbullying Sensitivity Levels of High School Students and Their Perceived Social Support Levels

    Science.gov (United States)

    Akturk, Ahmet Oguz

    2015-01-01

    Purpose: The purpose of this paper is to determine the cyberbullying sensitivity levels of high school students and their perceived social supports levels, and analyze the variables that predict cyberbullying sensitivity. In addition, whether cyberbullying sensitivity levels and social support levels differed according to gender was also…

  14. Sunburn as a Cause of Unexpected Neutrophilia in a Healthy Pregnant Woman

    Directory of Open Access Journals (Sweden)

    Robert Harper

    2018-01-01

    Full Text Available Background. Neutrophilia has a broad differential diagnosis and represents a systemic response to an infection or other inflammatory pathologies. Case. A 31-year-old woman, Gravida 3, Para 2 at 28 weeks of gestation, presented to the day assessment unit following routine blood tests that showed an unexpected marked neutrophilia. The underlying cause of the neutrophilia was sunburn. The sunburn recovered and her neutrophil count spontaneously normalised. Conclusion. Clinicians can add sunburn to the broad differential diagnosis of neutrophilia.

  15. Managing the nation's commercial high-level radioactive waste

    International Nuclear Information System (INIS)

    1985-03-01

    This report presents the findings and conclusions of OTA's analysis of Federal policy for the management of commercial high-level radioactive waste. It represents a major update and expansion of the Analysis presented to Congress in our summary report, Managing Commercial High-Level Radioactive Waste, published in April of 1982 (NWPA). This new report is intended to contribute to the implementation of NWPA, and in particular to Congressional review of three major documents that DOE will submit to the 99th Congress: a Mission Plan for the waste management program; a monitored retrievable storage (MRS) proposal; and a report on mechanisms for financing and managing the waste program. The assessment was originally focused on the ocean disposal of nuclear waste. OTA later broadened the study to include all aspects of high-level waste disposal. The major findings of the original analysis were published in OTA's 1982 summary report

  16. Unexpected perturbations training improves balance control and voluntary stepping times in older adults - a double blind randomized control trial.

    Science.gov (United States)

    Kurz, Ilan; Gimmon, Yoav; Shapiro, Amir; Debi, Ronen; Snir, Yoram; Melzer, Itshak

    2016-03-04

    Falls are common among elderly, most of them occur while slipping or tripping during walking. We aimed to explore whether a training program that incorporates unexpected loss of balance during walking able to improve risk factors for falls. In a double-blind randomized controlled trial 53 community dwelling older adults (age 80.1±5.6 years), were recruited and randomly allocated to an intervention group (n = 27) or a control group (n = 26). The intervention group received 24 training sessions over 3 months that included unexpected perturbation of balance exercises during treadmill walking. The control group performed treadmill walking with no perturbations. The primary outcome measures were the voluntary step execution times, traditional postural sway parameters and Stabilogram-Diffusion Analysis. The secondary outcome measures were the fall efficacy Scale (FES), self-reported late life function (LLFDI), and Performance-Oriented Mobility Assessment (POMA). Compared to control, participation in intervention program that includes unexpected loss of balance during walking led to faster Voluntary Step Execution Times under single (p = 0.002; effect size [ES] =0.75) and dual task (p = 0.003; [ES] = 0.89) conditions; intervention group subjects showed improvement in Short-term Effective diffusion coefficients in the mediolateral direction of the Stabilogram-Diffusion Analysis under eyes closed conditions (p = 0.012, [ES] = 0.92). Compared to control there were no significant changes in FES, LLFDI, and POMA. An intervention program that includes unexpected loss of balance during walking can improve voluntary stepping times and balance control, both previously reported as risk factors for falls. This however, did not transferred to a change self-reported function and FES. ClinicalTrials.gov NCT01439451 .

  17. High level cognitive information processing in neural networks

    Science.gov (United States)

    Barnden, John A.; Fields, Christopher A.

    1992-01-01

    Two related research efforts were addressed: (1) high-level connectionist cognitive modeling; and (2) local neural circuit modeling. The goals of the first effort were to develop connectionist models of high-level cognitive processes such as problem solving or natural language understanding, and to understand the computational requirements of such models. The goals of the second effort were to develop biologically-realistic model of local neural circuits, and to understand the computational behavior of such models. In keeping with the nature of NASA's Innovative Research Program, all the work conducted under the grant was highly innovative. For instance, the following ideas, all summarized, are contributions to the study of connectionist/neural networks: (1) the temporal-winner-take-all, relative-position encoding, and pattern-similarity association techniques; (2) the importation of logical combinators into connection; (3) the use of analogy-based reasoning as a bridge across the gap between the traditional symbolic paradigm and the connectionist paradigm; and (4) the application of connectionism to the domain of belief representation/reasoning. The work on local neural circuit modeling also departs significantly from the work of related researchers. In particular, its concentration on low-level neural phenomena that could support high-level cognitive processing is unusual within the area of biological local circuit modeling, and also serves to expand the horizons of the artificial neural net field.

  18. Evaluation of conditioned high-level waste forms

    International Nuclear Information System (INIS)

    Mendel, J.E.; Turcotte, R.P.; Chikalla, T.D.; Hench, L.L.

    1983-01-01

    The evaluation of conditioned high-level waste forms requires an understanding of radiation and thermal effects, mechanical properties, volatility, and chemical durability. As a result of nuclear waste research and development programs in many countries, a good understanding of these factors is available for borosilicate glass containing high-level waste. The IAEA through its coordinated research program has contributed to this understanding. Methods used in the evaluation of conditioned high-level waste forms are reviewed. In the US, this evaluation has been facilitated by the definition of standard test methods by the Materials Characterization Center (MCC), which was established by the Department of Energy (DOE) in 1979. The DOE has also established a 20-member Materials Review Board to peer-review the activities of the MCC. In addition to comparing waste forms, testing must be done to evaluate the behavior of waste forms in geologic repositories. Such testing is complex; accelerated tests are required to predict expected behavior for thousands of years. The tests must be multicomponent tests to ensure that all potential interactions between waste form, canister/overpack and corrosion products, backfill, intruding ground water and the repository rock, are accounted for. An overview of the status of such multicomponent testing is presented

  19. High-level waste management technology program plan

    Energy Technology Data Exchange (ETDEWEB)

    Harmon, H.D.

    1995-01-01

    The purpose of this plan is to document the integrated technology program plan for the Savannah River Site (SRS) High-Level Waste (HLW) Management System. The mission of the SRS HLW System is to receive and store SRS high-level wastes in a see and environmentally sound, and to convert these wastes into forms suitable for final disposal. These final disposal forms are borosilicate glass to be sent to the Federal Repository, Saltstone grout to be disposed of on site, and treated waste water to be released to the environment via a permitted outfall. Thus, the technology development activities described herein are those activities required to enable successful accomplishment of this mission. The technology program is based on specific needs of the SRS HLW System and organized following the systems engineering level 3 functions. Technology needs for each level 3 function are listed as reference, enhancements, and alternatives. Finally, FY-95 funding, deliverables, and schedules are s in Chapter IV with details on the specific tasks that are funded in FY-95 provided in Appendix A. The information in this report represents the vision of activities as defined at the beginning of the fiscal year. Depending on emergent issues, funding changes, and other factors, programs and milestones may be adjusted during the fiscal year. The FY-95 SRS HLW technology program strongly emphasizes startup support for the Defense Waste Processing Facility and In-Tank Precipitation. Closure of technical issues associated with these operations has been given highest priority. Consequently, efforts on longer term enhancements and alternatives are receiving minimal funding. However, High-Level Waste Management is committed to participation in the national Radioactive Waste Tank Remediation Technology Focus Area. 4 refs., 5 figs., 9 tabs.

  20. High-level waste management technology program plan

    International Nuclear Information System (INIS)

    Harmon, H.D.

    1995-01-01

    The purpose of this plan is to document the integrated technology program plan for the Savannah River Site (SRS) High-Level Waste (HLW) Management System. The mission of the SRS HLW System is to receive and store SRS high-level wastes in a see and environmentally sound, and to convert these wastes into forms suitable for final disposal. These final disposal forms are borosilicate glass to be sent to the Federal Repository, Saltstone grout to be disposed of on site, and treated waste water to be released to the environment via a permitted outfall. Thus, the technology development activities described herein are those activities required to enable successful accomplishment of this mission. The technology program is based on specific needs of the SRS HLW System and organized following the systems engineering level 3 functions. Technology needs for each level 3 function are listed as reference, enhancements, and alternatives. Finally, FY-95 funding, deliverables, and schedules are s in Chapter IV with details on the specific tasks that are funded in FY-95 provided in Appendix A. The information in this report represents the vision of activities as defined at the beginning of the fiscal year. Depending on emergent issues, funding changes, and other factors, programs and milestones may be adjusted during the fiscal year. The FY-95 SRS HLW technology program strongly emphasizes startup support for the Defense Waste Processing Facility and In-Tank Precipitation. Closure of technical issues associated with these operations has been given highest priority. Consequently, efforts on longer term enhancements and alternatives are receiving minimal funding. However, High-Level Waste Management is committed to participation in the national Radioactive Waste Tank Remediation Technology Focus Area. 4 refs., 5 figs., 9 tabs

  1. Unexpected Maternal Convulsion: An Idiopathic Case of Posterior Reversible Encephalopathy Syndrome after Delivery

    Directory of Open Access Journals (Sweden)

    Jila Agah

    2016-01-01

    Full Text Available Posterior reversible encephalopathy syndrome (PRES is associated with various clinical manifestations such as headache, blurred vision, confusion and tonic-clonic convulsion. Some of the predisposing factors for PRES include hypertensive encephalopathy, preeclampsia and eclampsia, lupus erythematosus, thrombotic thrombocytopenic purpura and long-term use of immunosuppressive drugs. This condition rarely occurs after normotensive and uneventful pregnancies. Several theories have been proposed on the etiology of PRES. For instance, endothelial injury and brain edema have been reported as possible causes of PRES. Although PRES is a temporary condition, proper and timely management of the disorder in the acute phase is critical for the prevention of permanent neurological complications. During pregnancy, PRES is normally accompanied with hypertension. In this paper, we present a rare case of PRES in a normotensive pregnancy in a 25-year-old parturient woman (Gravida 2, Ab 1. The patient unexpectedly manifested symptoms of tonic-clonic convulsion one hour after an uneventful vaginal delivery, which were successfully managed. According to our observations, PRES has various clinical manifestations with unexpected occurrence in some cases. Therefore, it is recommended that maternity centers be well-equipped with resuscitation tools, emergency drugs and expert staff so as to manage unforeseen PRES efficiently and prevent permanent maternal neurological complications and mortality.

  2. Department of Energy pretreatment of high-level and low-level wastes

    International Nuclear Information System (INIS)

    McGinnis, C.P.; Hunt, R.D.

    1995-01-01

    The remediation of the 1 x 10 8 gal of highly radioactive waste in the underground storage tanks (USTs) at five US Department of Energy (DOE) sites is one of DOE's greatest challenges. Therefore, the DOE Office of Environmental Management has created the Tank Focus Area (TFA) to manage an integrated technology development program that results in the safe and efficient remediation of UST waste. The TFA has divided its efforts into five areas, which are safety, characterization, retrieval/closure, pretreatment, and immobilization. All DOE pretreatment activities are integrated by the Pretreatment Technical Integration Manager of the TFA. For FY 1996, the 14 pretreatment tasks are divided into 3 systems: supernate separations, sludge treatment, and solid/liquid separation. The plans and recent results of these TFA tasks, which include two 25,000-gal demonstrations and two former TFA tasks on Cs removal, are presented. The pretreatment goals are to minimize the volume of high-level waste and the radioactivity in low-level waste

  3. Unexpected structure in the E2 quasicontinuum spectrum of 154Dy

    International Nuclear Information System (INIS)

    Holzmann, R.; Khoo, T.L.; Ma, W.C.

    1988-01-01

    The evolution of the γ quasicontinuum spectrum with neutron number has been investigated in the sequence of dysprosium isotopes /sup 152,154,156/Dy. The three nuclei display a pronounced collective E2 component. In 154 Dy this component shows an unexpected splitting into two distinct parts, signifying a structural change along the γ cascade. The E2 and statistical components can be reproduced in simple γ cascade calculations; in 152 Dy and 156 Dy only rotational bands were included, whereas in 154 Dy additional vibration-like transitions were required to reproduce the two E2 peaks. 11 refs., 2 figs

  4. High level radioactive wastes: Considerations on final disposal

    International Nuclear Information System (INIS)

    Ciallella, Norberto R.

    2000-01-01

    When at the beginnings of the decade of the 80 the National Commission on Atomic Energy (CNEA) in Argentina decided to study the destination of the high level radioactive wastes, was began many investigations, analysis and multidisciplinary evaluations that be origin to a study of characteristics never before carried out in Argentina. For the first time in the country was faced the study of an environmental eventual problem, several decades before that the problem was presented. The elimination of the high level radioactive wastes in the technological aspects was taken in advance, avoiding to transfer the problems to the future generations. The decision was based, not only in technical evaluations but also in ethical premises, since it was considered that the future generations may enjoy the benefits of the nuclear energy and not should be solve the problem. The CNEA in Argentina in 1980 decided to begin a feasibility study and preliminary engineering project for the construction of the final disposal of high level radioactive wastes

  5. Techniques for the solidification of high-level wastes

    International Nuclear Information System (INIS)

    1977-01-01

    The problem of the long-term management of the high-level wastes from the reprocessing of irradiated nuclear fuel is receiving world-wide attention. While the majority of the waste solutions from the reprocessing of commercial fuels are currently being stored in stainless-steel tanks, increasing effort is being devoted to developing technology for the conversion of these wastes into solids. A number of full-scale solidification facilities are expected to come into operation in the next decade. The object of this report is to survey and compare all the work currently in progress on the techniques available for the solidification of high-level wastes. It will examine the high-level liquid wastes arising from the various processes currently under development or in operation, the advantages and disadvantages of each process for different types and quantities of waste solutions, the stages of development, the scale-up potential and flexibility of the processes

  6. Transmission Level High Temperature Superconducting Fault Current Limiter

    Energy Technology Data Exchange (ETDEWEB)

    Stewart, Gary [SuperPower, Inc., Schenectady, NY (United States)

    2016-10-05

    The primary objective of this project was to demonstrate the feasibility and reliability of utilizing high-temperature superconducting (HTS) materials in a Transmission Level Superconducting Fault Current Limiter (SFCL) application. During the project, the type of high-temperature superconducting material used evolved from 1st generation (1G) BSCCO-2212 melt cast bulk high-temperature superconductors to 2nd generation (2G) YBCO-based high-temperature superconducting tape. The SFCL employed SuperPower's “Matrix” technology, that offers modular features to enable scale up to transmission voltage levels. The SFCL consists of individual modules that contain elements and parallel inductors that assist in carrying the current during the fault. A number of these modules are arranged in an m x n array to form the current-limiting matrix.

  7. Materials for high-level waste containment

    International Nuclear Information System (INIS)

    Marsh, G.P.

    1982-01-01

    The function of the high-level radioactive waste container in storage and of a container/overpack combination in disposal is considered. The consequent properties required from potential fabrication materials are discussed. The strategy adopted in selecting containment materials and the experimental programme underway to evaluate them are described. (U.K.)

  8. Psilocybin impairs high-level but not low-level motion perception.

    Science.gov (United States)

    Carter, Olivia L; Pettigrew, John D; Burr, David C; Alais, David; Hasler, Felix; Vollenweider, Franz X

    2004-08-26

    The hallucinogenic serotonin(1A&2A) agonist psilocybin is known for its ability to induce illusions of motion in otherwise stationary objects or textured surfaces. This study investigated the effect of psilocybin on local and global motion processing in nine human volunteers. Using a forced choice direction of motion discrimination task we show that psilocybin selectively impairs coherence sensitivity for random dot patterns, likely mediated by high-level global motion detectors, but not contrast sensitivity for drifting gratings, believed to be mediated by low-level detectors. These results are in line with those observed within schizophrenic populations and are discussed in respect to the proposition that psilocybin may provide a model to investigate clinical psychosis and the pharmacological underpinnings of visual perception in normal populations.

  9. 76 FR 53295 - Unexpected Urgent Refugee and Migration Needs Related to the Horn of Africa

    Science.gov (United States)

    2011-08-25

    ...-12 of August 8, 2011--Unexpected Urgent Refugee and Migration Needs Related to the Horn of Africa... Migration Needs Related to the Horn of Africa Memorandum for the Secretary of State By the authority vested... Department of State, related to the humanitarian crisis in the Horn of Africa. You are authorized and...

  10. Approximate Bisimulation for High-Level Datapaths in Intelligent Transportation Systems

    Directory of Open Access Journals (Sweden)

    Hui Deng

    2013-01-01

    Full Text Available A relation called approximate bisimulation is proposed to achieve behavior and structure optimization for a type of high-level datapath whose data exchange processes are expressed by nonlinear polynomial systems. The high-level datapaths are divided into small blocks with a partitioning method and then represented by polynomial transition systems. A standardized form based on Ritt-Wu's method is developed to represent the equivalence relation for the high-level datapaths. Furthermore, we establish an approximate bisimulation relation within a controllable error range and express the approximation with an error control function, which is processed by Sostools. Meanwhile, the error is controlled through tuning the equivalence restrictions. An example of high-level datapaths demonstrates the efficiency of our method.

  11. High-Level Waste (HLW) Feed Process Control Strategy

    International Nuclear Information System (INIS)

    STAEHR, T.W.

    2000-01-01

    The primary purpose of this document is to describe the overall process control strategy for monitoring and controlling the functions associated with the Phase 1B high-level waste feed delivery. This document provides the basis for process monitoring and control functions and requirements needed throughput the double-shell tank system during Phase 1 high-level waste feed delivery. This document is intended to be used by (1) the developers of the future Process Control Plan and (2) the developers of the monitoring and control system

  12. Treatment technologies for non-high-level wastes (USA)

    International Nuclear Information System (INIS)

    Cooley, C.R.; Clark, D.E.

    1976-06-01

    Non-high-level waste arising from operations at nuclear reactors, fuel fabrication facilities, and reprocessing facilities can be treated using one of several technical alternatives prior to storage. Each alternative and the associated experience and status of development are summarized. The technology for treating non-high-level wastes is generally available for industrial use. Improved techniques applicable to the commercial nuclear fuel cycle are being developed and demonstrated to reduce the volume of waste and to immobilize it for storage. 36 figures, 59 references

  13. Removing high-level contaminants

    International Nuclear Information System (INIS)

    Wallace, Paula

    2013-01-01

    Full text: Using biomimicry, an Australian cleantech innovation making inroads intoChinas's industrial sector offers multiple benefits to miners and processors in Australia. Stephen Shelley, the executive chairman of Creative Water Technology (CWT), was on hand at a recent trade show to explain how his Melbourne company has developed world-class techniques in zero liquid discharge and fractional crystallization of minerals to apply to a wide range of water treatment and recycling applications. “Most existing technologies operate with high energy distillation, filters or biological processing. CWT's appliance uses a low temperature, thermal distillation process known as adiabatic recovery to desalinate, dewater and/or recycle highly saline and highly contaminated waste water,” said Shelley. The technology has been specifically designed to handle the high levels of contaminant that alternative technologies struggle to process, with proven water quality results for feed water samples with TDS levels over 300,000ppm converted to clean water with less than 20ppm. Comparatively, reverse osmosis struggles to process contaminant levels over 70,000ppm effectively. “CWT is able to reclaim up to 97% clean usable water and up to 100% of the contaminants contained in the feed water,” said Shelley, adding that soluble and insoluble contaminants are separately extracted and dried for sale or re-use. In industrial applications CWT has successfully processed feed water with contaminant levels over 650,000 mg/1- without the use of chemicals. “The technology would be suitable for companies in oil exploration and production, mining, smelting, biofuels, textiles and the agricultural and food production sectors,” said Shelley. When compared to a conventional desalination plant, the CWT system is able to capture the value in the brine that most plants discard, not only from the salt but the additional water it contains. “If you recover those two commodities... then you

  14. Unexpected and just missed: the separate influence of the appraisals of expectancy and proximity on negative emotions.

    Science.gov (United States)

    Bossuyt, Evelien; Moors, Agnes; De Houwer, Jan

    2014-04-01

    Previous research has suggested that a goal-incongruent outcome leads to more intense negative emotions when it is unexpected and close to a goal-congruent outcome. Until now, however, no studies have disentangled the influence of the appraisals of expectancy and proximity on emotions. We experimentally manipulated each of these variables in 3 slot machine experiments and measured emotions via differences in motivation (i.e., the tendency to repair the goal incongruence) and feelings (i.e., disappointment, frustration, and anger). The experiments consisted of a series of trials that each started with the sequential presentation of 3 symbols. In case of a win trial, all symbols were equal (e.g., AAA) and the participant gained 10 cents; in case of a loss trial, one or more of the symbols differed and the participant gained 0 cents. Three different loss trials were compared: unexpected proximal ones (e.g., AAB), expected proximal ones (e.g., ABA), and expected distal ones (e.g., ABC). The tendency to repair was measured online via behavior as well as retrospectively via self-reports; feelings were measured retrospectively (Experiments 1 and 2) or online (Experiment 3). Unexpected losses seemed to increase the tendency to repair as well as feelings of disappointment (in all experiments) and feelings of frustration and anger (in Experiments 1 and 3). Proximal losses increased only the tendency to repair (in all experiments). This suggests that the appraisals of expectancy and proximity have a distinct influence on emotions.

  15. Elevated level of polysaccharides in a high level UV-B tolerant cell ...

    African Journals Online (AJOL)

    Jane

    2011-04-26

    Apr 26, 2011 ... A cell line of Bupleurum scorzonerifolium Willd with high level ... mechanisms to repair UV-induced damages via repairing ... for treatment or prevention of solar radiation. ..... working as both UV-B absorbing compounds and.

  16. Sequence tagging reveals unexpected modifications in toxicoproteomics

    Science.gov (United States)

    Dasari, Surendra; Chambers, Matthew C.; Codreanu, Simona G.; Liebler, Daniel C.; Collins, Ben C.; Pennington, Stephen R.; Gallagher, William M.; Tabb, David L.

    2010-01-01

    Toxicoproteomic samples are rich in posttranslational modifications (PTMs) of proteins. Identifying these modifications via standard database searching can incur significant performance penalties. Here we describe the latest developments in TagRecon, an algorithm that leverages inferred sequence tags to identify modified peptides in toxicoproteomic data sets. TagRecon identifies known modifications more effectively than the MyriMatch database search engine. TagRecon outperformed state of the art software in recognizing unanticipated modifications from LTQ, Orbitrap, and QTOF data sets. We developed user-friendly software for detecting persistent mass shifts from samples. We follow a three-step strategy for detecting unanticipated PTMs in samples. First, we identify the proteins present in the sample with a standard database search. Next, identified proteins are interrogated for unexpected PTMs with a sequence tag-based search. Finally, additional evidence is gathered for the detected mass shifts with a refinement search. Application of this technology on toxicoproteomic data sets revealed unintended cross-reactions between proteins and sample processing reagents. Twenty five proteins in rat liver showed signs of oxidative stress when exposed to potentially toxic drugs. These results demonstrate the value of mining toxicoproteomic data sets for modifications. PMID:21214251

  17. Magnetoresistance peculiarities of bismuth wires in high magnetic field

    Energy Technology Data Exchange (ETDEWEB)

    Condrea, E., E-mail: condrea@nano.asm.md [Institute of Electronic Engineering and Nanotechnologies, Academy of Science of Moldova, 2028 Chisinau, Republic of Moldova (Moldova, Republic of); International Laboratory of High Magnetic Fields and Low Temperatures, Gajowicka 95, 51-421 Wroclaw (Poland); Gilewski, A. [International Laboratory of High Magnetic Fields and Low Temperatures, Gajowicka 95, 51-421 Wroclaw (Poland); MagNet, 50-421 Wroclaw (Poland); Nicorici, A. [Institute of Electronic Engineering and Nanotechnologies, Academy of Science of Moldova, 2028 Chisinau, Republic of Moldova (Moldova, Republic of)

    2016-03-11

    Magnetoresistance measurements of Bi wires performed in the magnetic field oriented along the bisector axis revealed unexpected anomalous peaks in a high magnetic field far above the quantum limit of the electrons. By combining a magnetic field and an uniaxial strain, we obtained a modification of the electronic structure; as a result, the quantum limit for light and heavy electrons is changed in a different way. For the case where heavy electrons are in the quantum limit, a correlation between the exit of the lowest Landau level of light electrons and the Lifshitz transition was found. - Highlights: • Glass-coated single-crystalline Bi wires attain high limit of elastic strain of up to 3.0%. • Selective modification of the electronic structure of Bi wires is obtained by combining a high magnetic field and uniaxial strain. • The correlation between the exit of the lowest Landau level of electrons and Lifshitz transition was found.

  18. Magnetoresistance peculiarities of bismuth wires in high magnetic field

    International Nuclear Information System (INIS)

    Condrea, E.; Gilewski, A.; Nicorici, A.

    2016-01-01

    Magnetoresistance measurements of Bi wires performed in the magnetic field oriented along the bisector axis revealed unexpected anomalous peaks in a high magnetic field far above the quantum limit of the electrons. By combining a magnetic field and an uniaxial strain, we obtained a modification of the electronic structure; as a result, the quantum limit for light and heavy electrons is changed in a different way. For the case where heavy electrons are in the quantum limit, a correlation between the exit of the lowest Landau level of light electrons and the Lifshitz transition was found. - Highlights: • Glass-coated single-crystalline Bi wires attain high limit of elastic strain of up to 3.0%. • Selective modification of the electronic structure of Bi wires is obtained by combining a high magnetic field and uniaxial strain. • The correlation between the exit of the lowest Landau level of electrons and Lifshitz transition was found.

  19. Age-related changes in posture response under a continuous and unexpected perturbation.

    Science.gov (United States)

    Tsai, Yi-Ching; Hsieh, Lin-Fen; Yang, Saiwei

    2014-01-22

    Aging is a critical factor to influence the functional performance during daily life. Without an appropriate posture control response when experiencing an unexpected external perturbation, fall may occur. A novel six-degree-of freedom platform with motion control protocol was designed to provide a real-life simulation of unexpected disturbance in order to discriminate the age-related changes of the balance control and the recovery ability. Twenty older adults and 20 healthy young adults participated in the study. The subjects stood barefoot on the novel movable platform, data of the center of mass (COM) excursion, joint rotation angle and electromyography (EMG) were recorded and compared. The results showed that the older adults had similar patterns of joint movement and COM excursion as the young adults during the balance reactive-recovery. However, larger proximal joint rotation in elderly group induced larger COM sway envelop and therefore loss of the compensatory strategy of posture recovery. The old adults also presented a lower muscle power. In order to keep an adequate joint stability preventing from falling, the EMG activity was increased, but the asymmetric pattern might be the key reason of unstable postural response. This novel design of moveable platform and test protocol comprised the computerized dynamic posturography (CDP) demonstrate its value to assess the possible sensory, motor, and central adaptive impairments to balance control and could be the training tool for posture inability person. © 2013 Elsevier Ltd. All rights reserved.

  20. Python based high-level synthesis compiler

    Science.gov (United States)

    Cieszewski, Radosław; Pozniak, Krzysztof; Romaniuk, Ryszard

    2014-11-01

    This paper presents a python based High-Level synthesis (HLS) compiler. The compiler interprets an algorithmic description of a desired behavior written in Python and map it to VHDL. FPGA combines many benefits of both software and ASIC implementations. Like software, the mapped circuit is flexible, and can be reconfigured over the lifetime of the system. FPGAs therefore have the potential to achieve far greater performance than software as a result of bypassing the fetch-decode-execute operations of traditional processors, and possibly exploiting a greater level of parallelism. Creating parallel programs implemented in FPGAs is not trivial. This article describes design, implementation and first results of created Python based compiler.

  1. Aeon: Synthesizing Scheduling Algorithms from High-Level Models

    Science.gov (United States)

    Monette, Jean-Noël; Deville, Yves; van Hentenryck, Pascal

    This paper describes the aeon system whose aim is to synthesize scheduling algorithms from high-level models. A eon, which is entirely written in comet, receives as input a high-level model for a scheduling application which is then analyzed to generate a dedicated scheduling algorithm exploiting the structure of the model. A eon provides a variety of synthesizers for generating complete or heuristic algorithms. Moreover, synthesizers are compositional, making it possible to generate complex hybrid algorithms naturally. Preliminary experimental results indicate that this approach may be competitive with state-of-the-art search algorithms.

  2. Unexpected variation in neuroanatomy among diverse nematode species

    Directory of Open Access Journals (Sweden)

    Ziduan eHan

    2016-01-01

    Full Text Available Nematodes are considered excellent models for understanding fundamental aspects of neuron function. However, nematodes are less frequently used as models for examining the evolution of nervous systems. While the habitats and behaviors of nematodes are diverse, the neuroanatomy of nematodes is often considered highly conserved. A small number of nematode species greatly influences our understanding of nematode neurobiology. The free-living species Caenorhabditis elegans and, to a lesser extent, the mammalian gastrointestinal parasite Ascaris suum are, historically, the primary sources of knowledge regarding nematode neurobiology. Despite differences in size and habitat, C. elegans and Ascaris suum share a surprisingly similar neuroanatomy. Here, we examined species across several clades in the phylum Nematoda and show that there is a surprising degree of neuroanatomical variation both within and among nematode clades when compared to C. elegans and Ascaris. We found variation in the numbers of neurons in the ventral nerve cord and dye-filling pattern of sensory neurons. For example, we found that Pristionchus pacificus, a bacterial feeding species used for comparative developmental research, had 20% fewer ventral cord neurons compared to C. elegans. Steinernema carpocapse, an insect-parasitic nematode capable of jumping behavior, had 40% more ventral cord neurons than C. elegans. Interestingly, the non-jumping congeneric nematode, S. glaseri showed an identical number of ventral cord neurons as S. carpocapsae. There was also variability in the timing of neurodevelopment of the ventral cord with two of five species that hatch as second-stage juveniles showing delayed neurodevelopment. We also found unexpected variation in the dye-filling of sensory neurons among examined species. Again, sensory neuron dye-filling pattern did not strictly correlate with phylogeny. Our results demonstrate that variation in nematode neuroanatomy is more prevalent

  3. Technetium Chemistry in High-Level Waste

    International Nuclear Information System (INIS)

    Hess, Nancy J.

    2006-01-01

    Tc contamination is found within the DOE complex at those sites whose mission involved extraction of plutonium from irradiated uranium fuel or isotopic enrichment of uranium. At the Hanford Site, chemical separations and extraction processes generated large amounts of high level and transuranic wastes that are currently stored in underground tanks. The waste from these extraction processes is currently stored in underground High Level Waste (HLW) tanks. However, the chemistry of the HLW in any given tank is greatly complicated by repeated efforts to reduce volume and recover isotopes. These processes ultimately resulted in mixing of waste streams from different processes. As a result, the chemistry and the fate of Tc in HLW tanks are not well understood. This lack of understanding has been made evident in the failed efforts to leach Tc from sludge and to remove Tc from supernatants prior to immobilization. Although recent interest in Tc chemistry has shifted from pretreatment chemistry to waste residuals, both needs are served by a fundamental understanding of Tc chemistry

  4. Unexpected optical limiting properties from MoS2 nanosheets modified by a semiconductive polymer.

    Science.gov (United States)

    Zhao, Min; Chang, Meng-Jie; Wang, Qiang; Zhu, Zhen-Tong; Zhai, Xin-Ping; Zirak, Mohammad; Moshfegh, Alireza Z; Song, Ying-Lin; Zhang, Hao-Li

    2015-08-07

    Direct solvent exfoliation of bulk MoS2 with the assistance of poly(3-hexylthiophene) (P3HT) produces a novel two-dimensional organic/inorganic semiconductor hetero-junction. The obtained P3HT-MoS2 nanohybrid exhibits unexpected optical limiting properties in contrast to the saturated absorption behavior of both P3HT and MoS2, showing potential in future photoelectric applications.

  5. Cobalt-catalyzed hydrogenation of esters to alcohols: unexpected reactivity trend indicates ester enolate intermediacy.

    Science.gov (United States)

    Srimani, Dipankar; Mukherjee, Arup; Goldberg, Alexander F G; Leitus, Gregory; Diskin-Posner, Yael; Shimon, Linda J W; Ben David, Yehoshoa; Milstein, David

    2015-10-12

    The atom-efficient and environmentally benign catalytic hydrogenation of carboxylic acid esters to alcohols has been accomplished in recent years mainly with precious-metal-based catalysts, with few exceptions. Presented here is the first cobalt-catalyzed hydrogenation of esters to the corresponding alcohols. Unexpectedly, the evidence indicates the unprecedented involvement of ester enolate intermediates. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. Handbook of high-level radioactive waste transportation

    International Nuclear Information System (INIS)

    Sattler, L.R.

    1992-10-01

    The High-Level Radioactive Waste Transportation Handbook serves as a reference to which state officials and members of the general public may turn for information on radioactive waste transportation and on the federal government's system for transporting this waste under the Civilian Radioactive Waste Management Program. The Handbook condenses and updates information contained in the Midwestern High-Level Radioactive Waste Transportation Primer. It is intended primarily to assist legislators who, in the future, may be called upon to enact legislation pertaining to the transportation of radioactive waste through their jurisdictions. The Handbook is divided into two sections. The first section places the federal government's program for transporting radioactive waste in context. It provides background information on nuclear waste production in the United States and traces the emergence of federal policy for disposing of radioactive waste. The second section covers the history of radioactive waste transportation; summarizes major pieces of legislation pertaining to the transportation of radioactive waste; and provides an overview of the radioactive waste transportation program developed by the US Department of Energy (DOE). To supplement this information, a summary of pertinent federal and state legislation and a glossary of terms are included as appendices, as is a list of publications produced by the Midwestern Office of The Council of State Governments (CSG-MW) as part of the Midwestern High-Level Radioactive Waste Transportation Project

  7. The lowest Landau level in QCD

    Directory of Open Access Journals (Sweden)

    Bruckmann Falk

    2017-01-01

    Full Text Available The thermodynamics of Quantum Chromodynamics (QCD in external (electro-magnetic fields shows some unexpected features like inverse magnetic catalysis, which have been revealed mainly through lattice studies. Many effective descriptions, on the other hand, use Landau levels or approximate the system by just the lowest Landau level (LLL. Analyzing lattice configurations we ask whether such a picture is justified. We find the LLL to be separated from the rest by a spectral gap in the two-dimensional Dirac operator and analyze the corresponding LLL signature in four dimensions. We determine to what extent the quark condensate is LLL dominated at strong magnetic fields.

  8. High estradiol levels improve false memory rates and meta-memory in highly schizotypal women.

    Science.gov (United States)

    Hodgetts, Sophie; Hausmann, Markus; Weis, Susanne

    2015-10-30

    Overconfidence in false memories is often found in patients with schizophrenia and healthy participants with high levels of schizotypy, indicating an impairment of meta-cognition within the memory domain. In general, cognitive control is suggested to be modulated by natural fluctuations in oestrogen. However, whether oestrogen exerts beneficial effects on meta-memory has not yet been investigated. The present study sought to provide evidence that high levels of schizotypy are associated with increased false memory rates and overconfidence in false memories, and that these processes may be modulated by natural differences in estradiol levels. Using the Deese-Roediger-McDermott paradigm, it was found that highly schizotypal participants with high estradiol produced significantly fewer false memories than those with low estradiol. No such difference was found within the low schizotypy participants. Highly schizotypal participants with high estradiol were also less confident in their false memories than those with low estradiol; low schizotypy participants with high estradiol were more confident. However, these differences only approached significance. These findings suggest that the beneficial effect of estradiol on memory and meta-memory observed in healthy participants is specific to highly schizotypal individuals and might be related to individual differences in baseline dopaminergic activity. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  9. Generation of Efficient High-Level Hardware Code from Dataflow Programs

    OpenAIRE

    Siret , Nicolas; Wipliez , Matthieu; Nezan , Jean François; Palumbo , Francesca

    2012-01-01

    High-level synthesis (HLS) aims at reducing the time-to-market by providing an automated design process that interprets and compiles high-level abstraction programs into hardware. However, HLS tools still face limitations regarding the performance of the generated code, due to the difficulties of compiling input imperative languages into efficient hardware code. Moreover the hardware code generated by the HLS tools is usually target-dependant and at a low level of abstraction (i.e. gate-level...

  10. Sudden unexpected infant death (SUDI in a newborn due to medium chain acyl CoA dehydrogenase (MCAD deficiency with an unusual severe genotype

    Directory of Open Access Journals (Sweden)

    Lovera Cristina

    2012-10-01

    Full Text Available Abstract Medium chain acyl CoA dehydrogenase deficiency (MCAD is the most common inborn error of fatty acid oxidation. This condition may lead to cellular energy shortage and cause severe clinical events such as hypoketotic hypoglycemia, Reye syndrome and sudden death. MCAD deficiency usually presents around three to six months of life, following catabolic stress as intercurrent infections or prolonged fasting, whilst neonatal-onset of the disease is quite rare. We report the case of an apparently healthy newborn who suddenly died at the third day of life, in which the diagnosis of MCAD deficiency was possible through peri-mortem blood-spot acylcarnitine analysis that showed very high concentrations of octanoylcarnitine. Genetic analysis at the ACADM locus confirmed the biochemical findings by demonstrating the presence in homozygosity of the frame-shift c.244dup1 (p.Trp82LeufsX23 mutation, a severe genotype that may explain the unusual and very early fatal outcome in this newborn. This report confirms that inborn errors of fatty acid oxidation represent one of the genetic causes of sudden unexpected deaths in infancy (SUDI and underlines the importance to include systematically specific metabolic screening in any neonatal unexpected death.

  11. Serum osteoprotegerin levels and mammographic density among high-risk women.

    Science.gov (United States)

    Moran, Olivia; Zaman, Tasnim; Eisen, Andrea; Demsky, Rochelle; Blackmore, Kristina; Knight, Julia A; Elser, Christine; Ginsburg, Ophira; Zbuk, Kevin; Yaffe, Martin; Narod, Steven A; Salmena, Leonardo; Kotsopoulos, Joanne

    2018-06-01

    Mammographic density is a risk factor for breast cancer but the mechanism behind this association is unclear. The receptor activator of nuclear factor κB (RANK)/RANK ligand (RANKL) pathway has been implicated in the development of breast cancer. Given the role of RANK signaling in mammary epithelial cell proliferation, we hypothesized this pathway may also be associated with mammographic density. Osteoprotegerin (OPG), a decoy receptor for RANKL, is known to inhibit RANK signaling. Thus, it is of interest to evaluate whether OPG levels modify breast cancer risk through mammographic density. We quantified serum OPG levels in 57 premenopausal and 43 postmenopausal women using an enzyme-linked immunosorbent assay (ELISA). Cumulus was used to measure percent density, dense area, and non-dense area for each mammographic image. Subjects were classified into high versus low OPG levels based on the median serum OPG level in the entire cohort (115.1 pg/mL). Multivariate models were used to assess the relationship between serum OPG levels and the measures of mammographic density. Serum OPG levels were not associated with mammographic density among premenopausal women (P ≥ 0.42). Among postmenopausal women, those with low serum OPG levels had higher mean percent mammographic density (20.9% vs. 13.7%; P = 0.04) and mean dense area (23.4 cm 2 vs. 15.2 cm 2 ; P = 0.02) compared to those with high serum OPG levels after covariate adjustment. These findings suggest that low OPG levels may be associated with high mammographic density, particularly in postmenopausal women. Targeting RANK signaling may represent a plausible, non-surgical prevention option for high-risk women with high mammographic density, especially those with low circulating OPG levels.

  12. Effect of high-oxygen and high-carbon-dioxide atmospheres on strawberry flavor and other quality traits.

    Science.gov (United States)

    Pérez, A G; Sanz, C

    2001-05-01

    The effect of high-oxygen atmospheres on strawberry flavor was studied. Strawberry fruits (Fragariax ananassa Duch. cv. Camarosa) were stored at 8 degrees C in four different atmospheres: air, 5% O(2)/20% CO(2), 80% O(2)/20% CO(2), and 90% O(2)/10% CO(2). Changes in several quality parameters were evaluated. Atmospheres combining high O(2) and high CO(2) were the most effective in preventing fungal growth and enhancing strawberry firmness. Other quality parameters such as color, titrable acidity, sugars and organic acids distribution, off-flavor development, and aroma were only mildly affected by superatmospheric O(2) levels. After one week of storage, unexpected high contents of off-flavor related compounds were found in the 80% O(2)/20% CO(2) and 90% O(2)/10% CO(2) atmospheres. Evidence of an altered ester biosynthesis was also found in fruits stored under these high-O(2) atmospheres. Data obtained suggest that stress induced by high CO(2) and stress induced by high O(2) have an additive effect on strawberry flavor alteration.

  13. Materials Science of High-Level Nuclear Waste Immobilization

    International Nuclear Information System (INIS)

    Weber, William J.; Navrotsky, Alexandra; Stefanovsky, S. V.; Vance, E. R.; Vernaz, Etienne Y.

    2009-01-01

    With the increasing demand for the development of more nuclear power comes the responsibility to address the technical challenges of immobilizing high-level nuclear wastes in stable solid forms for interim storage or disposition in geologic repositories. The immobilization of high-level nuclear wastes has been an active area of research and development for over 50 years. Borosilicate glasses and complex ceramic composites have been developed to meet many technical challenges and current needs, although regulatory issues, which vary widely from country to country, have yet to be resolved. Cooperative international programs to develop advanced proliferation-resistant nuclear technologies to close the nuclear fuel cycle and increase the efficiency of nuclear energy production might create new separation waste streams that could demand new concepts and materials for nuclear waste immobilization. This article reviews the current state-of-the-art understanding regarding the materials science of glasses and ceramics for the immobilization of high-level nuclear waste and excess nuclear materials and discusses approaches to address new waste streams

  14. The immobilization of High Level Waste Into Glass

    International Nuclear Information System (INIS)

    Aisyah; Martono, H.

    1998-01-01

    High level liquid waste is generated from the first step extraction in the nuclear fuel reprocessing. The waste is immobilized with boro-silicate glass. A certain composition of glass is needed for a certain type of waste, so that the properties of waste glass would meet the requirement either for further process or for disposal. The effect of waste loading on either density, thermal expansion, softening point and leaching rate has been studied. The composition of the high level liquid waste has been determined by ORIGEN 2 and the result has been used to prepare simulated high level waste. The waste loading in the waste glass has been set to be 19.48; 22.32; 25.27; and 26.59 weight percent. The result shows that increasing the waste loading has resulted in the higher density with no thermal expansion and softening point significant change. The increase in the waste loading increase that leaching rate. The properties of the waste glass in this research have not shown any deviation from the standard waste glass properties

  15. Transfusion rate and prevalence of unexpected red blood cell alloantibodies in women undergoing hysterectomy for benign disease

    DEFF Research Database (Denmark)

    Thoestesen, Lisbeth M; Rasmussen, Kjeld L; Lauszus, Finn F

    2011-01-01

    To determine transfusion rates, risk factors for transfusion and the prevalence of unexpected red blood cell alloantibodies in women undergoing hysterectomy for benign disease. In addition, we aimed to evaluate the necessity of the pretransfusion testing for red blood cell alloantibodies....

  16. The own and social effects of an unexpected income shock: Evidence from the Dutch Postcode Lottery

    NARCIS (Netherlands)

    Kuhn, P.J.; Kooreman, P.; Soetevent, A.R.; Kapteyn, A.

    2008-01-01

    In the Dutch Postcode Lottery a postal code (19 households on average) is randomly selected weekly, and prizes - consisting of cash and a new BMW - are awarded to lottery participants living in that postal code. On average, this generates a temporary, unexpected income shock equal to about eight

  17. Understanding unexpected courses of multiple sclerosis among patients using complementary and alternative medicine: A travel from recipient to explorer

    Directory of Open Access Journals (Sweden)

    Anita Salamonsen

    2010-07-01

    Full Text Available Complementary and alternative medicine (CAM is frequently used by patients with multiple sclerosis (MS. Some MS patients experience unexpected improvements of symptoms, which they relate to their use of CAM. The aim of this study was to obtain knowledge and develop understandings of such self-defined unexpected improvement of MS symptoms. Two cases were constructed based on documents and 12 qualitative interviews. Our aim was not to make generalisations from the cases, but to transfer knowledge as working hypotheses. We identified four health-related change processes: the process of losing bodily competence; the process of developing responsibility; the process of taking control; and the process of choosing CAM. The patients explained unexpected improvements in their MS symptoms as results of their own efforts including their choice and use of CAM. In our theoretical interpretations, we found the patients’ redefinition of history, the concept of treatment and the importance of conventional health care to be essential, and leading to a change of patients’ position towards conventional health care from recipients to explorers. The explorers can be perceived as boundary walkers reflecting limitations within the conventional health care system and as initiators regarding what MS patients find useful in CAM.

  18. ONDRAF/NIRAS and high-level radioactive waste management in Belgium

    International Nuclear Information System (INIS)

    Decamps, F.

    1993-01-01

    The National Agency for Radioactive Waste and Enriched Fissile Materials, ONDRAF/NIRAS, is a public body with legal personality in charge of managing all radioactive waste on Belgian territory, regardless of its origin and source. It is also entrusted with tasks related to the management of enriched fissile materials, plutonium containing materials and used or unused nuclear fuel, and with certain aspects of the dismantling of closed down nuclear facilities. High-level radioactive waste management comprises essentially and for the time being the storage of high-level liquid waste produced by the former EUROCHEMIC reprocessing plant and of high-level and very high-level heat producing waste resulting from the reprocessing in France of Belgian spent fuel, as well as research and development (R and D) with regard to geological disposal in clay of this waste type

  19. Hanford long-term high-level waste management program overview

    International Nuclear Information System (INIS)

    Reep, I.E.

    1978-05-01

    The objective is the long-term disposition of the defense high-level radioactive waste which will remain upon completion of the interim waste management program in the mid-1980s, plus any additional high-level defense waste resulting from the future operation of N Reactor and the Purex Plant. The high-level radioactive waste which will exist in the mid-1980s and is addressed by this plan consists of approximately 3,300,000 ft 3 of damp salt cake stored in single-shell and double-shell waste tanks, 1,500,000 ft 3 of damp sludge stored in single-shell and double-shell waste tanks, 11,000,000 gallons of residual liquor stored in double-shell waste tanks, 3,000,000 gallons of liquid wastes stored in double-shell waste tanks awaiting solidification, and 2,900 capsules of 90 SR and 137 Cs compounds stored in water basins. Final quantities of waste may be 5 to 10% greater, depending on the future operation of N Reactor and the Purex Plant and the application of waste treatment techniques currently under study to reduce the inventory of residual liquor. In this report, the high-level radioactive waste addressed by this plan is briefly described, the major alternatives and strategies for long-term waste management are discussed, and a description of the long-term high-level waste management program is presented. Separate plans are being prepared for the long-term management of radioactive wastes which exist in other forms. 14 figures

  20. An unexpected evolution of symptomatic mild middle cerebral artery (MCA stenosis: asymptomatic occlusion

    Directory of Open Access Journals (Sweden)

    Malferrari Giovanni

    2011-12-01

    Full Text Available Abstract Background The intracranial localization of large artery disease is recognized as the main cause of ischemic stroke in the world, considering all countries, although its global burden is widely underestimated. Indeed it has been reported more frequently in Asians and African-American people, but the finding of intracranial stenosis as a cause of ischemic stroke is relatively common also in Caucasians. The prognosis of patients with stroke due to intracranial steno-occlusion is strictly dependent on the time of recanalization. Moreover, the course of the vessel involvement is highly dynamic in both directions, improvement or worsening, although several data are derived from the atherosclerotic subtype, compared to other causes. Case description We report the clinical, neurosonological and neuroradiological findings of a young woman, who came to our Stroke Unit because of the abrupt onset of aphasia during her work. An urgent neurosonological examination showed a left M1 MCA stenosis, congruent with the presenting symptoms; magnetic resonance imaging confirmed this finding and identified an acute ischemic lesion on the left MCA territory. The past history of the patient was significant only for a hyperinsulinemic condition, treated with metformine, and a mild overweight. At this time a selective cerebral angiography was not performed because of the patient refusal and she was discharged on antiplatelet and lipid-lowering therapy, having failed to identify autoimmune or inflammatory diseases. Within 1 month, she went back to our attention because of the recurrence of aphasia, lasting about ten minutes. Neuroimaging findings were unchanged, but the patient accepted to undergo a selective cerebral angiography, which showed a mild left distal M1 MCA stenosis. During the follow-up the patient did not experienced any recurrence, but a routine neurosonological examination found an unexpected evolution of the known MCA stenosis, i.e. left M1 MCA

  1. Interlimb communication following unexpected changes in treadmill velocity during human walking

    DEFF Research Database (Denmark)

    Stevenson, Andrew James Thomas; Geertsen, Svend Sparre; Sinkjær, Thomas

    2015-01-01

    Interlimb reflexes play an important role in human walking, particularly when dynamic stability is threatened by external perturbations or changes in the walking surface. Interlimb reflexes have recently been demonstrated in the contralateral biceps femoris (cBF) following knee joint rotations...... applied to the ipsilateral leg (iKnee) during the late stance phase of human gait (Stevenson et al. 2013). This interlimb reflex likely acts to slow the forward progression of the body in order to maintain dynamic stability following the perturbations. We examined this hypothesis by unexpectedly...... to slow the forward progression of the body and maintaining dynamic stability during walking, thus signifying a functional role for interlimb reflexes....

  2. Why don't you like me? Midfrontal theta power in response to unexpected peer rejection feedback.

    Science.gov (United States)

    van der Molen, M J W; Dekkers, L M S; Westenberg, P M; van der Veen, F M; van der Molen, M W

    2017-02-01

    Social connectedness theory posits that the brain processes social rejection as a threat to survival. Recent electrophysiological evidence suggests that midfrontal theta (4-8Hz) oscillations in the EEG provide a window on the processing of social rejection. Here we examined midfrontal theta dynamics (power and inter-trial phase synchrony) during the processing of social evaluative feedback. We employed the Social Judgment paradigm in which 56 undergraduate women (mean age=19.67 years) were asked to communicate their expectancies about being liked vs. disliked by unknown peers. Expectancies were followed by feedback indicating social acceptance vs. rejection. Results revealed a significant increase in EEG theta power to unexpected social rejection feedback. This EEG theta response could be source-localized to brain regions typically reported during activation of the saliency network (i.e., dorsal anterior cingulate cortex, insula, inferior frontal gyrus, frontal pole, and the supplementary motor area). Theta phase dynamics mimicked the behavior of the time-domain averaged feedback-related negativity (FRN) by showing stronger phase synchrony for feedback that was unexpected vs. expected. Theta phase, however, differed from the FRN by also displaying stronger phase synchrony in response to rejection vs. acceptance feedback. Together, this study highlights distinct roles for midfrontal theta power and phase synchrony in response to social evaluative feedback. Our findings contribute to the literature by showing that midfrontal theta oscillatory power is sensitive to social rejection but only when peer rejection is unexpected, and this theta response is governed by a widely distributed neural network implicated in saliency detection and conflict monitoring. Copyright © 2016 Elsevier Inc. All rights reserved.

  3. Final report on cermet high-level waste forms

    International Nuclear Information System (INIS)

    Kobisk, E.H.; Quinby, T.C.; Aaron, W.S.

    1981-08-01

    Cermets are being developed as an alternate method for the fixation of defense and commercial high level radioactive waste in a terminal disposal form. Following initial feasibility assessments of this waste form, consisting of ceramic particles dispersed in an iron-nickel base alloy, significantly improved processing methods were developed. The characterization of cermets has continued through property determinations on samples prepared by various methods from a variety of simulated and actual high-level wastes. This report describes the status of development of the cermet waste form as it has evolved since 1977. 6 tables, 18 figures

  4. High level radioactive waste management facility design criteria

    International Nuclear Information System (INIS)

    Sheikh, N.A.; Salaymeh, S.R.

    1993-01-01

    This paper discusses the engineering systems for the structural design of the Defense Waste Processing Facility (DWPF) at the Savannah River Site (SRS). At the DWPF, high level radioactive liquids will be mixed with glass particles and heated in a melter. This molten glass will then be poured into stainless steel canisters where it will harden. This process will transform the high level waste into a more stable, manageable substance. This paper discuss the structural design requirements for this unique one of a kind facility. A special emphasis will be concentrated on the design criteria pertaining to earthquake, wind and tornado, and flooding

  5. Ontology-Based High-Level Context Inference for Human Behavior Identification

    Science.gov (United States)

    Villalonga, Claudia; Razzaq, Muhammad Asif; Khan, Wajahat Ali; Pomares, Hector; Rojas, Ignacio; Lee, Sungyoung; Banos, Oresti

    2016-01-01

    Recent years have witnessed a huge progress in the automatic identification of individual primitives of human behavior, such as activities or locations. However, the complex nature of human behavior demands more abstract contextual information for its analysis. This work presents an ontology-based method that combines low-level primitives of behavior, namely activity, locations and emotions, unprecedented to date, to intelligently derive more meaningful high-level context information. The paper contributes with a new open ontology describing both low-level and high-level context information, as well as their relationships. Furthermore, a framework building on the developed ontology and reasoning models is presented and evaluated. The proposed method proves to be robust while identifying high-level contexts even in the event of erroneously-detected low-level contexts. Despite reasonable inference times being obtained for a relevant set of users and instances, additional work is required to scale to long-term scenarios with a large number of users. PMID:27690050

  6. Ontology-Based High-Level Context Inference for Human Behavior Identification

    Directory of Open Access Journals (Sweden)

    Claudia Villalonga

    2016-09-01

    Full Text Available Recent years have witnessed a huge progress in the automatic identification of individual primitives of human behavior, such as activities or locations. However, the complex nature of human behavior demands more abstract contextual information for its analysis. This work presents an ontology-based method that combines low-level primitives of behavior, namely activity, locations and emotions, unprecedented to date, to intelligently derive more meaningful high-level context information. The paper contributes with a new open ontology describing both low-level and high-level context information, as well as their relationships. Furthermore, a framework building on the developed ontology and reasoning models is presented and evaluated. The proposed method proves to be robust while identifying high-level contexts even in the event of erroneously-detected low-level contexts. Despite reasonable inference times being obtained for a relevant set of users and instances, additional work is required to scale to long-term scenarios with a large number of users.

  7. Geographical distribution of drinking-water with high iodine level and association between high iodine level in drinking-water and goitre: a Chinese national investigation.

    Science.gov (United States)

    Shen, Hongmei; Liu, Shoujun; Sun, Dianjun; Zhang, Shubin; Su, Xiaohui; Shen, Yanfeng; Han, Hepeng

    2011-07-01

    Excessive iodine intake can cause thyroid function disorders as can be caused by iodine deficiency. There are many people residing in areas with high iodine levels in drinking-water in China. The main aim of the present study was to map the geographical distribution of drinking-water with high iodine level in China and to determine the relationship between high iodine level in drinking-water and goitre prevalence. Iodine in drinking-water was measured in 1978 towns of eleven provinces in China, with a total of 28,857 water samples. We randomly selected children of 8-10 years old, examined the presence of goitre and measured their urinary iodine in 299 towns of nine provinces. Of the 1978 towns studied, 488 had iodine levels between 150 and 300 μg/l in drinking-water, and in 246 towns, the iodine level was >300 μg/l. These towns are mainly distributed along the original Yellow River flood areas, the second largest river in China. Of the 56 751 children examined, goitre prevalence was 6.3 % in the areas with drinking-water iodine levels of 150-300 μg/l and 11.0 % in the areas with drinking-water iodine >300 μg/l. Goitre prevalence increased with water and urinary iodine levels. For children with urinary iodine >1500 μg/l, goitre prevalence was 3.69 times higher than that for those with urinary iodine levels of 100-199 μg/l. The present study suggests that drinking-water with high iodine levels is distributed in eleven provinces of China. Goitre becomes more prevalent with the increase in iodine level in drinking-water. Therefore, it becomes important to prevent goitre through stopping the provision of iodised salt and providing normal drinking-water iodine through pipelines in these areas in China.

  8. Magnetoresistance peculiarities of bismuth wires in high magnetic field

    Science.gov (United States)

    Condrea, E.; Gilewski, A.; Nicorici, A.

    2016-03-01

    Magnetoresistance measurements of Bi wires performed in the magnetic field oriented along the bisector axis revealed unexpected anomalous peaks in a high magnetic field far above the quantum limit of the electrons. By combining a magnetic field and an uniaxial strain, we obtained a modification of the electronic structure; as a result, the quantum limit for light and heavy electrons is changed in a different way. For the case where heavy electrons are in the quantum limit, a correlation between the exit of the lowest Landau level of light electrons and the Lifshitz transition was found.

  9. PAIRWISE BLENDING OF HIGH LEVEL WASTE

    International Nuclear Information System (INIS)

    CERTA, P.J.

    2006-01-01

    The primary objective of this study is to demonstrate a mission scenario that uses pairwise and incidental blending of high level waste (HLW) to reduce the total mass of HLW glass. Secondary objectives include understanding how recent refinements to the tank waste inventory and solubility assumptions affect the mass of HLW glass and how logistical constraints may affect the efficacy of HLW blending

  10. High-level radioactive wastes. Supplement 1

    International Nuclear Information System (INIS)

    McLaren, L.H.

    1984-09-01

    This bibliography contains information on high-level radioactive wastes included in the Department of Energy's Energy Data Base from August 1982 through December 1983. These citations are to research reports, journal articles, books, patents, theses, and conference papers from worldwide sources. Five indexes, each preceded by a brief description, are provided: Corporate Author, Personal Author, Subject, Contract Number, and Report Number. 1452 citations

  11. A high Tc superconducting liquid nitrogen level sensor

    International Nuclear Information System (INIS)

    Jin, J. X.; Liu, H. K.; Dou, S. X.; Grantham, C.; Beer, J.

    1996-01-01

    Full text: The dramatic resistance change in the superconducting-normal transition temperature range enables a high T c superconductor to be considered for designing a liquid nitrogen level sensor. A (Bi,Pb) 2 Sr 2 Ca 2 Cu 3 O 10+x Ag clad superconducting wire is selected and tested as a continuous liquid nitrogen level sensor to investigate the possibility for this application. The (Bi,Pb) 2 Sr 2 Ca 2 Cu 3 O 10+x Ag clad superconducting wire has approximately 110 K critical temperature, with more flexible and stable properties compared with bulk shape ceramic high T c superconductors. The voltage drops across the sensor are tested with different immersion lengths in liquid nitrogen. The accuracy of the HTS sensor is analysed with its dR/dT in the superconducting-normal transition range. The voltage signal is sensitive to liquid nitrogen level change, and this signal can be optimized by controlling the transport current. The problems of the Ag clad superconductor are that the Ag sheath thermal conductivity is very high, and the sensor normal resistance is low. These are the main disadvantages for using such a wire as a continuous level sensor. However, a satisfactory accuracy can be achieved by control of the transport current. A different configuration of the wire sensor is also designed to avoid this thermal influence

  12. Multi-threaded algorithms for GPGPU in the ATLAS High Level Trigger

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00212700; The ATLAS collaboration

    2017-01-01

    General purpose Graphics Processor Units (GPGPU) are being evaluated for possible future inclusion in an upgraded ATLAS High Level Trigger farm. We have developed a demonstrator including GPGPU implementations of Inner Detector and Muon tracking and Calorimeter clustering within the ATLAS software framework. ATLAS is a general purpose particle physics experiment located on the LHC collider at CERN. The ATLAS Trigger system consists of two levels, with Level-1 implemented in hardware and the High Level Trigger implemented in software running on a farm of commodity CPU. The High Level Trigger reduces the trigger rate from the 100 kHz Level-1 acceptance rate to 1.5 kHz for recording, requiring an average per-event processing time of ∼ 250 ms for this task. The selection in the high level trigger is based on reconstructing tracks in the Inner Detector and Muon Spectrometer and clusters of energy deposited in the Calorimeter. Performing this reconstruction within the available farm resources presents a significa...

  13. Platinum-nanoparticle-supported core-shell polymer nanospheres with unexpected water stability and facile further modification

    Science.gov (United States)

    Yuan, Conghui; Xu, Yiting; Luo, Weiang; Zeng, Birong; Qiu, Wuhui; Liu, Jie; Huang, Huiling; Dai, Lizong

    2012-05-01

    Core-shell nanospheres (CSNSs) with hydrophobic cores and hydrophilic shells were fabricated via a simple mini-emulsion polymerization for the stabilization of platinum nanoparticles (Pt-NPs). The CSNSs showed extremely high loading capacity of Pt-NPs (the largest loading amount of the Pt-NPs was about 49.2 wt%). Importantly, the Pt-NPs/CSNSs nanocomposites had unexpected stability in aqueous solution. DLS results revealed that the CSNSs loaded with Pt-NPs exhibited almost no aggregation after standing for a long time . However, the Pt-NPs immobilized on the CSNSs were not straitlaced: they could transport and redistribute between CSNSs freely when the environmental temperature was higher than the melting point of the CSNS shell. Owing to their excellent stability in aqueous solution, the surface of the Pt-NPs/CSNSs nanocomposites could be further decorated easily. For example, polyaniline (PANI)-coated Pt-NPs/CSNSs, nickel (Ni)-coated Pt-NPs/CSNSs and PANI/Pt-NPs dual-layer hollow nanospheres were facilely fabricated from the Pt-NPs/CSNS nanocomposites.

  14. Platinum-nanoparticle-supported core–shell polymer nanospheres with unexpected water stability and facile further modification

    International Nuclear Information System (INIS)

    Yuan Conghui; Xu Yiting; Luo Weiang; Zeng Birong; Qiu Wuhui; Liu Jie; Dai Lizong; Huang Huiling

    2012-01-01

    Core–shell nanospheres (CSNSs) with hydrophobic cores and hydrophilic shells were fabricated via a simple mini-emulsion polymerization for the stabilization of platinum nanoparticles (Pt-NPs). The CSNSs showed extremely high loading capacity of Pt-NPs (the largest loading amount of the Pt-NPs was about 49.2 wt%). Importantly, the Pt-NPs/CSNSs nanocomposites had unexpected stability in aqueous solution. DLS results revealed that the CSNSs loaded with Pt-NPs exhibited almost no aggregation after standing for a long time . However, the Pt-NPs immobilized on the CSNSs were not straitlaced: they could transport and redistribute between CSNSs freely when the environmental temperature was higher than the melting point of the CSNS shell. Owing to their excellent stability in aqueous solution, the surface of the Pt-NPs/CSNSs nanocomposites could be further decorated easily. For example, polyaniline (PANI)-coated Pt-NPs/CSNSs, nickel (Ni)-coated Pt-NPs/CSNSs and PANI/Pt-NPs dual-layer hollow nanospheres were facilely fabricated from the Pt-NPs/CSNS nanocomposites. (paper)

  15. Engineering materials for high level radioactive waste repository

    International Nuclear Information System (INIS)

    Wen Zhijian

    2009-01-01

    Radioactive wastes can arise from a wide range of human activities and have different physical and chemical forms with various radioactivity. The high level radioactive wastes (HLW)are characterized by nuclides of very high initial radioactivity, large thermal emissivity and the long life-term. The HLW disposal is highly concerned by the scientists and the public in the world. At present, the deep geological disposal is regarded as the most reasonable and effective way to safely dispose high-level radioactive wastes in the world. The conceptual model of HLW geological disposal in China is based on a multi-barrier system that combines an isolating geological environment with an engineering barrier system(EBS). The engineering materials in EBS include the vitrified HLW, canister, overpack, buffer materials and backfill materials. Referring to progress in the world, this paper presents the function, the requirement for material selection and design, and main scientific projects of R and D of engineering materials in HLW repository. (authors)

  16. Cermets for high level waste containment

    International Nuclear Information System (INIS)

    Aaron, W.S.; Quinby, T.C.; Kobisk, E.H.

    1978-01-01

    Cermet materials are currently under investigation as an alternate for the primary containment of high level wastes. The cermet in this study is an iron--nickel base metal matrix containing uniformly dispersed, micron-size fission product oxides, aluminosilicates, and titanates. Cermets possess high thermal conductivity, and typical waste loading of 70 wt % with volume reduction factors of 2 to 200 and low processing volatility losses have been realized. Preliminary leach studies indicate a leach resistance comparable to other candidate waste forms; however, more quantitative data are required. Actual waste studies have begun on NFS Acid Thorex, SRP dried sludge and fresh, unneutralized SRP process wastes

  17. The Influence of Decreased Levels of High Density Lipoprotein ...

    African Journals Online (AJOL)

    Background: Changes in lipoproteins levels in sickle cell disease (SCD) patients are well.known, but the physiological ramifications of the low levels observed have not been entirely resolved. Aim: The aim of this study is to evaluate the impact of decreased levels of high density lipoprotein cholesterol (HDL.c) on ...

  18. Treatment of High-Level Waste Arising from Pyrochemical Processes

    International Nuclear Information System (INIS)

    Lizin, A.A.; Kormilitsyn, M.V.; Osipenko, A.G.; Tomilin, S.V.; Lavrinovich, Yu.G.

    2013-01-01

    JSC “SSC RIAR” has been performing research and development activities in support of closed fuel cycle of fast reactor since the middle of 1960s. Fuel cycle involves fabrication and reprocessing of spent nuclear fuel (SNF) using pyrochemical methods of reprocessing in molten alkali metal chlorides. At present pyrochemical methods of SNF reprocessing in molten chlorides has reached such a level in their development that makes it possible to compare their competitiveness with classic aqueous methods. Their comparative advantage lies in high safety, compactness, high protectability as to nonproliferation of nuclear materials, and reduction of high level waste volume

  19. Very-high-level neutral-beam control system

    International Nuclear Information System (INIS)

    Elischer, V.; Jacobson, V.; Theil, E.

    1981-10-01

    As increasing numbers of neutral beams are added to fusion machines, their operation can consume a significant fraction of a facility's total resources. LBL has developed a very high level control system that allows a neutral beam injector to be treated as a black box with just 2 controls: one to set the beam power and one to set the pulse duration. This 2 knob view allows simple operation and provides a natural base for implementing even higher level controls such as automatic source conditioning

  20. High-level radioactive wastes. Supplement 1

    Energy Technology Data Exchange (ETDEWEB)

    McLaren, L.H. (ed.)

    1984-09-01

    This bibliography contains information on high-level radioactive wastes included in the Department of Energy's Energy Data Base from August 1982 through December 1983. These citations are to research reports, journal articles, books, patents, theses, and conference papers from worldwide sources. Five indexes, each preceded by a brief description, are provided: Corporate Author, Personal Author, Subject, Contract Number, and Report Number. 1452 citations.

  1. Decommissioning high-level waste surface facilities

    International Nuclear Information System (INIS)

    1978-04-01

    The protective storage, entombment and dismantlement options of decommissioning a High-Level Waste Surface Facility (HLWSF) was investigated. A reference conceptual design for the facility was developed based on the designs of similar facilities. State-of-the-art decommissioning technologies were identified. Program plans and cost estimates for decommissioning the reference conceptual designs were developed. Good engineering design concepts were on the basis of this work identified

  2. Copper imbalances in ruminants and humans: unexpected common ground.

    Science.gov (United States)

    Suttle, Neville F

    2012-09-01

    Ruminants are more vulnerable to copper deficiency than humans because rumen sulfide generation lowers copper availability from forage, increasing the risk of conditions such as swayback in lambs. Molybdenum-rich pastures promote thiomolybdate (TM) synthesis and formation of unabsorbable Cu-TM complexes, turning risk to clinical reality (hypocuprosis). Selection pressures created ruminant species with tolerance of deficiency but vulnerability to copper toxicity in alien environments, such as specific pathogen-free units. By contrast, cases of copper imbalance in humans seemed confined to rare genetic aberrations of copper metabolism. Recent descriptions of human swayback and the exploratory use of TM for the treatment of Wilson's disease, tumor growth, inflammatory diseases, and Alzheimer's disease have created unexpected common ground. The incidence of pre-hemolytic copper poisoning in specific pathogen-free lambs was reduced by an infection with Mycobacterium avium that left them more responsive to treatment with TM but vulnerable to long-term copper depletion. Copper requirements in ruminants and humans may need an extra allowance for the "copper cost" of immunity to infection. Residual cuproenzyme inhibition in TM-treated lambs and anomalies in plasma copper composition that appeared to depend on liver copper status raise this question "can chelating capacity be harnessed without inducing copper-deficiency in ruminants or humans?" A model of equilibria between exogenous (TM) and endogenous chelators (e.g., albumin, metallothionein) is used to predict risk of exposure and hypocuprosis; although risk of natural exposure in humans is remote, vulnerability to TM-induced copper deficiency may be high. Biomarkers of TM impact are needed, and copper chaperones for inhibited cuproenzymes are prime candidates.

  3. Spontaneous abortion and unexpected death: a critical discussion of Marquis on abortion.

    Science.gov (United States)

    Coleman, Mary Clayton

    2013-02-01

    In his classic paper, 'Why abortion is immoral', Don Marquis argues that what makes killing an adult seriously immoral is that it deprives the victim of the valuable future he/she would have otherwise had. Moreover, Marquis contends, because abortion deprives a fetus of the very same thing, aborting a fetus is just as seriously wrong as killing an adult. Marquis' argument has received a great deal of critical attention in the two decades since its publication. Nonetheless, there is a potential challenge to it that seems to have gone unnoticed. A significant percentage of fetuses are lost to spontaneous abortion. Once we bring this fact to our attention, it becomes less clear whether Marquis can use his account of the wrongness of killing to show that abortion is the moral equivalent of murder. In this paper, I explore the relevance of the rate of spontaneous abortion to Marquis' classic anti-abortion argument. I introduce a case I call Unexpected Death in which someone is about to commit murder, but, just as the would-be murderer is about to strike, his would-be victim dies unexpectedly. I then ask: what does Marquis' account of killing imply about the moral status of what the would-be murderer was about to do? I consider four responses Marquis could give to this question, and I examine what implications these responses have for Marquis' strategy of using his account of the wrongness of killing an adult to show that abortion is in the same moral category.

  4. Low Power Design with High-Level Power Estimation and Power-Aware Synthesis

    CERN Document Server

    Ahuja, Sumit; Shukla, Sandeep Kumar

    2012-01-01

    Low-power ASIC/FPGA based designs are important due to the need for extended battery life, reduced form factor, and lower packaging and cooling costs for electronic devices. These products require fast turnaround time because of the increasing demand for handheld electronic devices such as cell-phones, PDAs and high performance machines for data centers. To achieve short time to market, design flows must facilitate a much shortened time-to-product requirement. High-level modeling, architectural exploration and direct synthesis of design from high level description enable this design process. This book presents novel research techniques, algorithms,methodologies and experimental results for high level power estimation and power aware high-level synthesis. Readers will learn to apply such techniques to enable design flows resulting in shorter time to market and successful low power ASIC/FPGA design. Integrates power estimation and reduction for high level synthesis, with low-power, high-level design; Shows spec...

  5. Interaction between High-Level and Low-Level Image Analysis for Semantic Video Object Extraction

    Directory of Open Access Journals (Sweden)

    Andrea Cavallaro

    2004-06-01

    Full Text Available The task of extracting a semantic video object is split into two subproblems, namely, object segmentation and region segmentation. Object segmentation relies on a priori assumptions, whereas region segmentation is data-driven and can be solved in an automatic manner. These two subproblems are not mutually independent, and they can benefit from interactions with each other. In this paper, a framework for such interaction is formulated. This representation scheme based on region segmentation and semantic segmentation is compatible with the view that image analysis and scene understanding problems can be decomposed into low-level and high-level tasks. Low-level tasks pertain to region-oriented processing, whereas the high-level tasks are closely related to object-level processing. This approach emulates the human visual system: what one “sees” in a scene depends on the scene itself (region segmentation as well as on the cognitive task (semantic segmentation at hand. The higher-level segmentation results in a partition corresponding to semantic video objects. Semantic video objects do not usually have invariant physical properties and the definition depends on the application. Hence, the definition incorporates complex domain-specific knowledge and is not easy to generalize. For the specific implementation used in this paper, motion is used as a clue to semantic information. In this framework, an automatic algorithm is presented for computing the semantic partition based on color change detection. The change detection strategy is designed to be immune to the sensor noise and local illumination variations. The lower-level segmentation identifies the partition corresponding to perceptually uniform regions. These regions are derived by clustering in an N-dimensional feature space, composed of static as well as dynamic image attributes. We propose an interaction mechanism between the semantic and the region partitions which allows to

  6. Coastal barrier stratigraphy for Holocene high-resolution sea-level reconstruction.

    Science.gov (United States)

    Costas, Susana; Ferreira, Óscar; Plomaritis, Theocharis A; Leorri, Eduardo

    2016-12-08

    The uncertainties surrounding present and future sea-level rise have revived the debate around sea-level changes through the deglaciation and mid- to late Holocene, from which arises a need for high-quality reconstructions of regional sea level. Here, we explore the stratigraphy of a sandy barrier to identify the best sea-level indicators and provide a new sea-level reconstruction for the central Portuguese coast over the past 6.5 ka. The selected indicators represent morphological features extracted from coastal barrier stratigraphy, beach berm and dune-beach contact. These features were mapped from high-resolution ground penetrating radar images of the subsurface and transformed into sea-level indicators through comparison with modern analogs and a chronology based on optically stimulated luminescence ages. Our reconstructions document a continuous but slow sea-level rise after 6.5 ka with an accumulated change in elevation of about 2 m. In the context of SW Europe, our results show good agreement with previous studies, including the Tagus isostatic model, with minor discrepancies that demand further improvement of regional models. This work reinforces the potential of barrier indicators to accurately reconstruct high-resolution mid- to late Holocene sea-level changes through simple approaches.

  7. ERP correlates of unexpected word forms in a picture–word study of infants and adults

    Science.gov (United States)

    Duta, M.D.; Styles, S.J.; Plunkett, K.

    2012-01-01

    We tested 14-month-olds and adults in an event-related potentials (ERPs) study in which pictures of familiar objects generated expectations about upcoming word forms. Expected word forms labelled the picture (word condition), while unexpected word forms mismatched by either a small deviation in word medial vowel height (mispronunciation condition) or a large deviation from the onset of the first speech segment (pseudoword condition). Both infants and adults showed sensitivity to both types of unexpected word form. Adults showed a chain of discrete effects: positivity over the N1 wave, negativity over the P2 wave (PMN effect) and negativity over the N2 wave (N400 effect). Infants showed a similar pattern, including a robust effect similar to the adult P2 effect. These observations were underpinned by a novel visualisation method which shows the dynamics of the ERP within bands of the scalp over time. The results demonstrate shared processing mechanisms across development, as even subtle deviations from expected word forms were indexed in both age groups by a reduction in the amplitude of characteristic waves in the early auditory evoked potential. PMID:22483072

  8. Unexpected Convergent Evolution of Nasal Domes between Pleistocene Bovids and Cretaceous Hadrosaur Dinosaurs.

    Science.gov (United States)

    O'Brien, Haley D; Faith, J Tyler; Jenkins, Kirsten E; Peppe, Daniel J; Plummer, Thomas W; Jacobs, Zenobia L; Li, Bo; Joannes-Boyau, Renaud; Price, Gilbert; Feng, Yue-Xing; Tryon, Christian A

    2016-02-22

    The fossil record provides tangible, historical evidence for the mode and operation of evolution across deep time. Striking patterns of convergence are some of the strongest examples of these operations, whereby, over time, similar environmental and/or behavioral pressures precipitate similarity in form and function between disparately related taxa. Here we present fossil evidence for an unexpected convergence between gregarious plant-eating mammals and dinosaurs. Recent excavations of Late Pleistocene deposits on Rusinga Island, Kenya, have uncovered a catastrophic assemblage of the wildebeest-like bovid Rusingoryx atopocranion. Previously known from fragmentary material, these new specimens reveal large, hollow, osseous nasal crests: a craniofacial novelty for mammals that is remarkably comparable to the nasal crests of lambeosaurine hadrosaur dinosaurs. Using adult and juvenile material from this assemblage, as well as computed tomographic imaging, we investigate this convergence from morphological, developmental, functional, and paleoenvironmental perspectives. Our detailed analyses reveal broad parallels between R. atopocranion and basal Lambeosaurinae, suggesting that osseous nasal crests may require a highly specific combination of ontogeny, evolution, and environmental pressures in order to develop. Copyright © 2016 Elsevier Ltd. All rights reserved.

  9. Volatility of ruthenium-106, technetium-99, and iodine-129, and the evolution of nitrogen oxide compounds during the calcination of high-level, radioactive nitric acid waste

    International Nuclear Information System (INIS)

    Rimshaw, S.J.; Case, F.N.; Tompkins, J.A.

    1980-02-01

    The nitrate anion is the predominant constituent in all high-level nuclear wastes. Formic acid reacts with the nitrate anion to yield noncondensable, inert gases (N 2 or N 2 O), which can be scrubbed free of 106 Ru, 129 I, and 99 Tc radioactivities prior to elimination from the plant by passing through HEPA filters. Treatment of a high-level authentic radioactive waste with two moles of formic acid per mole of nitrate anion leads to a low RuO 4 volatility of about 0.1%, which can be reduced to an even lower level of 0.007% on adding a 15% excess of formic acid. Without pretreatment of the nitrate waste with formic acid, a high RuO 4 volatility of approx. 35% is observed on calcining a 4.0 N HNO 3 solution in quartz equipment at 350 0 C. The RuO 4 volatility falls to approx. 1.0% on decreasing the initial HNO 3 concentration to 1.0 N or lower. It is postulated that thermal denitration of a highly nitrated ruthenium complex leads to the formation of volatile RuO 4 , while decarboxylation of a ruthenium-formate complex leads to the formation of nonvolatile RuO 2 . Wet scrubbing with water is used to remove RuO 4 from the off-gas stream. In all glass equipment, small amounts of particulate RuO 2 are formed in the gas phase by decomposition of RuO 4 . The 99 Tc volatility was found to vary from 0.2 to 1.4% on calcining HNO 3 and HCOOH (formic acid) solutions over the temperature range of 250 to 600 0 C. These unexpectedly low volatilities of 99 Tc are correlated to the high thermal stability limits of various metal pertechnetates and technetates. Iodine volatilities were high, varying from a low of 30% at 350 0 C to a high of 97% at 650 0 C. It is concluded that with a proper selection of pretreatment and operating conditions the 106 Ru and 99 Tc activities can be retained in the calcined solid with recycle of the wet scrubbing solution

  10. Performance of the CMS High Level Trigger

    CERN Document Server

    Perrotta, Andrea

    2015-01-01

    The CMS experiment has been designed with a 2-level trigger system. The first level is implemented using custom-designed electronics. The second level is the so-called High Level Trigger (HLT), a streamlined version of the CMS offline reconstruction software running on a computer farm. For Run II of the Large Hadron Collider, the increases in center-of-mass energy and luminosity will raise the event rate to a level challenging for the HLT algorithms. The increase in the number of interactions per bunch crossing, on average 25 in 2012, and expected to be around 40 in Run II, will be an additional complication. We present here the expected performance of the main triggers that will be used during the 2015 data taking campaign, paying particular attention to the new approaches that have been developed to cope with the challenges of the new run. This includes improvements in HLT electron and photon reconstruction as well as better performing muon triggers. We will also present the performance of the improved trac...

  11. Determination of total cyanide in Hanford Site high-level wastes

    Energy Technology Data Exchange (ETDEWEB)

    Winters, W.I. [Westinghouse Hanford Co., Richland, WA (United States); Pool, K.H. [Pacific Northwest Lab., Richland, WA (United States)

    1994-05-01

    Nickel ferrocyanide compounds (Na{sub 2-x}Cs{sub x}NiFe (CN){sub 6}) were produced in a scavenging process to remove {sup 137}Cs from Hanford Site single-shell tank waste supernates. Methods for determining total cyanide in Hanford Site high-level wastes are needed for the evaluation of potential exothermic reactions between cyanide and oxidizers such as nitrate and for safe storage, processing, and management of the wastes in compliance with regulatory requirements. Hanford Site laboratory experience in determining cyanide in high-level wastes is summarized. Modifications were made to standard cyanide methods to permit improved handling of high-level waste samples and to eliminate interferences found in Hanford Site waste matrices. Interferences and associated procedure modifications caused by high nitrates/nitrite concentrations, insoluble nickel ferrocyanides, and organic complexants are described.

  12. Determination of total cyanide in Hanford Site high-level wastes

    International Nuclear Information System (INIS)

    Winters, W.I.; Pool, K.H.

    1994-05-01

    Nickel ferrocyanide compounds (Na 2-x Cs x NiFe (CN) 6 ) were produced in a scavenging process to remove 137 Cs from Hanford Site single-shell tank waste supernates. Methods for determining total cyanide in Hanford Site high-level wastes are needed for the evaluation of potential exothermic reactions between cyanide and oxidizers such as nitrate and for safe storage, processing, and management of the wastes in compliance with regulatory requirements. Hanford Site laboratory experience in determining cyanide in high-level wastes is summarized. Modifications were made to standard cyanide methods to permit improved handling of high-level waste samples and to eliminate interferences found in Hanford Site waste matrices. Interferences and associated procedure modifications caused by high nitrates/nitrite concentrations, insoluble nickel ferrocyanides, and organic complexants are described

  13. Type GQS-1 high pressure steam manifold water level monitoring system

    International Nuclear Information System (INIS)

    Li Nianzu; Li Beicheng; Jia Shengming

    1993-10-01

    The GQS-1 high pressure steam manifold water level monitoring system is an advanced nuclear gauge that is suitable for on-line detecting and monitor in high pressure steam manifold water level. The physical variable of water level is transformed into electrical pulses by the nuclear sensor. A computer is equipped for data acquisition, analysis and processing and the results are displayed on a 14 inch color monitor. In addition, a 4 ∼ 20 mA output current is used for the recording and regulation of water level. The main application of this gauge is for on-line measurement of high pressure steam manifold water level in fossil-fired power plant and other industries

  14. High-level trigger system for the LHC ALICE experiment

    CERN Document Server

    Bramm, R; Lien, J A; Lindenstruth, V; Loizides, C; Röhrich, D; Skaali, B; Steinbeck, T M; Stock, Reinhard; Ullaland, K; Vestbø, A S; Wiebalck, A

    2003-01-01

    The central detectors of the ALICE experiment at LHC will produce a data size of up to 75 MB/event at an event rate less than approximately equals 200 Hz resulting in a data rate of similar to 15 GB/s. Online processing of the data is necessary in order to select interesting (sub)events ("High Level Trigger"), or to compress data efficiently by modeling techniques. Processing this data requires a massive parallel computing system (High Level Trigger System). The system will consist of a farm of clustered SMP-nodes based on off- the-shelf PCs connected with a high bandwidth low latency network.

  15. Hip Arthroscopy in High-Level Baseball Players.

    Science.gov (United States)

    Byrd, J W Thomas; Jones, Kay S

    2015-08-01

    To report the results of hip arthroscopy among high-level baseball players as recorded by outcome scores and return to baseball. All patients undergoing hip arthroscopy were prospectively assessed with the modified Harris Hip Score. On review of all procedures performed over a 12-year period, 44 hips were identified among 41 intercollegiate or professional baseball players who had achieved 2-year follow-up. Among the 41 players, follow-up averaged 45 months (range, 24 to 120 months), with a mean age of 23 years (range, 18 to 34 years). There were 23 collegiate (1 bilateral) and 18 professional (2 bilateral) baseball players, including 10 Major League Baseball players. Of the 8 Major League Baseball pitchers, 6 (75%) also underwent ulnar collateral ligament elbow surgery. Improvement in the modified Harris Hip Score averaged 13 points (from 81 points preoperatively to 94 points postoperatively); a paired-samples t test determined that this mean improvement of 13 points was statistically significant (P arthroscopy. This study supports the idea that arthroscopic treatment for a variety of hip pathologies in high-level baseball players provides a successful return to sport and improvement in functional outcome scores. Level IV, therapeutic case series. Copyright © 2015 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

  16. Space augmentation of military high-level waste disposal

    International Nuclear Information System (INIS)

    English, T.; Lees, L.; Divita, E.

    1979-01-01

    Space disposal of selected components of military high-level waste (HLW) is considered. This disposal option offers the promise of eliminating the long-lived radionuclides in military HLW from the earth. A space mission which meets the dual requirements of long-term orbital stability and a maximum of one space shuttle launch per week over a period of 20-40 years, is a heliocentric orbit about halfway between the orbits of earth and Venus. Space disposal of high-level radioactive waste is characterized by long-term predicability and short-term uncertainties which must be reduced to acceptably low levels. For example, failure of either the Orbit Transfer Vehicle after leaving low earth orbit, or the storable propellant stage failure at perihelion would leave the nuclear waste package in an unplanned and potentially unstable orbit. Since potential earth reencounter and subsequent burn-up in the earth's atmosphere is unacceptable, a deep space rendezvous, docking, and retrieval capability must be developed

  17. Development of high-level waste solidification technology 1

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Joon Hyung; Kim, Hwan Young; Kim, In Tae [and others

    1999-02-01

    Spent nuclear fuel contains useful nuclides as valuable resource materials for energy, heat and catalyst. High-level wastes (HLW) are expected to be generated from the R and D activities and reuse processes. It is necessary to develop vitrification or advanced solidification technologies for the safe long-term management of high level wastes. As a first step to establish HLW vitrification technology, characterization of HLWs that would arise at KAERI site, glass melting experiments with a lab-scale high frequency induction melter, and fabrication and property evaluation of base-glass made of used HEPA filter media and additives were performed. Basic study on the fabrication and characterization of candidate ceramic waste form (Synroc) was also carried out. These HLW solidification technologies would be directly useful for carrying out the R and Ds on the nuclear fuel cycle and waste management. (author). 70 refs., 29 tabs., 35 figs.

  18. Bah humbug: Unexpected Christmas cards and the reciprocity norm.

    Science.gov (United States)

    Meier, Brian P

    2016-01-01

    The reciprocity norm refers to the expectation that people will help those who helped them. A well-known study revealed that the norm is strong with Christmas cards, with 20% of people reciprocating a Christmas card received from a stranger. I attempted to conceptually replicate and extend this effect. In Study 1, 755 participants received a Christmas card supposedly from a more- versus less-similar stranger. The reciprocation rate was unexpectedly low (2%), which did not allow for a test of a similarity effect. Two potential reasons for this low rate were examined in Study 2 in which 494 participants reported their likelihood of reciprocating a Christmas card from a stranger as well as their felt suspicions/threat about the card and their frequency of e-mail use. Reciprocation likelihood was negatively correlated with perceived threat/suspicion and e-mail use. It appears that reciprocating a gift from a stranger in offline settings may be less likely than expected.

  19. Unexpectedly large charge radii of neutron-rich calcium isotopes

    CERN Document Server

    Garcia Ruiz, R F; Blaum, K; Ekström, A; Frömmgen, N; Hagen, G; Hammen, M; Hebeler, K; Holt, J D; Jansen, G R; Kowalska, M; Kreim, K; Nazarewicz, W; Neugart, R; Neyens, G; Nörtershäuser, W; Papenbrock, T; Papuga, J; Schwenk, A; Simonis, J; Wendt, K A; Yordanov, D T

    2016-01-01

    Despite being a complex many-body system, the atomic nucleus exhibits simple structures for certain ‘magic’ numbers of protons and neutrons. The calcium chain in particular is both unique and puzzling: evidence of doubly magic features are known in 40,48Ca, and recently suggested in two radioactive isotopes, 52,54Ca. Although many properties of experimentally known calcium isotopes have been successfully described by nuclear theory, it is still a challenge to predict the evolution of their charge radii. Here we present the first measurements of the charge radii of 49,51,52Ca, obtained from laser spectroscopy experiments at ISOLDE, CERN. The experimental results are complemented by state-of-the-art theoretical calculations. The large and unexpected increase of the size of the neutron-rich calcium isotopes beyond N = 28 challenges the doubly magic nature of 52Ca and opens new intriguing questions on the evolution of nuclear sizes away from stability, which are of importance for our understanding of neutron-...

  20. The CMS High Level Trigger System

    CERN Document Server

    Afaq, A; Bauer, G; Biery, K; Boyer, V; Branson, J; Brett, A; Cano, E; Carboni, A; Cheung, H; Ciganek, M; Cittolin, S; Dagenhart, W; Erhan, S; Gigi, D; Glege, F; Gómez-Reino, Robert; Gulmini, M; Gutiérrez-Mlot, E; Gutleber, J; Jacobs, C; Kim, J C; Klute, M; Kowalkowski, J; Lipeles, E; Lopez-Perez, Juan Antonio; Maron, G; Meijers, F; Meschi, E; Moser, R; Murray, S; Oh, A; Orsini, L; Paus, C; Petrucci, A; Pieri, M; Pollet, L; Rácz, A; Sakulin, H; Sani, M; Schieferdecker, P; Schwick, C; Sexton-Kennedy, E; Sumorok, K; Suzuki, I; Tsirigkas, D; Varela, J

    2007-01-01

    The CMS Data Acquisition (DAQ) System relies on a purely software driven High Level Trigger (HLT) to reduce the full Level-1 accept rate of 100 kHz to approximately 100 Hz for archiving and later offline analysis. The HLT operates on the full information of events assembled by an event builder collecting detector data from the CMS front-end systems. The HLT software consists of a sequence of reconstruction and filtering modules executed on a farm of O(1000) CPUs built from commodity hardware. This paper presents the architecture of the CMS HLT, which integrates the CMS reconstruction framework in the online environment. The mechanisms to configure, control, and monitor the Filter Farm and the procedures to validate the filtering code within the DAQ environment are described.

  1. Processing vessel for high level radioactive wastes

    International Nuclear Information System (INIS)

    Maekawa, Hiromichi

    1998-01-01

    Upon transferring an overpack having canisters containing high level radioactive wastes sealed therein and burying it into an underground processing hole, an outer shell vessel comprising a steel plate to be fit and contained in the processing hole is formed. A bury-back layer made of dug earth and sand which had been discharged upon forming the processing hole is formed on the inner circumferential wall of the outer shell vessel. A buffer layer having a predetermined thickness is formed on the inner side of the bury-back layer, and the overpack is contained in the hollow portion surrounded by the layer. The opened upper portion of the hollow portion is covered with the buffer layer and the bury-back layer. Since the processing vessel having a shielding performance previously formed on the ground, the state of packing can be observed. In addition, since an operator can directly operates upon transportation and burying of the high level radioactive wastes, remote control is no more necessary. (T.M.)

  2. Solidification of Savannah River Plant high level waste

    International Nuclear Information System (INIS)

    Maher, R.; Shafranek, L.F.; Kelley, J.A.; Zeyfang, R.W.

    1981-11-01

    Authorization for construction of the Defense Waste Processing Facility (DWPF) is expected in FY 83. The optimum time for stage 2 authorization is about three years later. Detailed design and construction will require approximately five years for stage 1, with stage 2 construction completed about two to three years later. Production of canisters of waste glass would begin in 1988, and the existing backlog of high level waste sludge stored at SRP would be worked off by about the year 2000. Stage 2 operation could begin in 1990. The technology and engineering are ready for construction and eventual operation of the DWPF for immobilizing high level radioactive waste at Savannah River Plant (SRP). Proceeding with this project will provide the public, and the leadership of this country, with a crucial demonstration that a major quantity of existing high level nuclear wastes can be safely and permanently immobilized. Early demonstration will both expedite and facilitate rational decision making on this aspect of the nuclear program. Delay in providing these facilities will result in significant DOE expenditures at SRP for new tanks just for continued temporary storage of wastes, and would probably result in dissipation of the intellectual and planning momentum that has built up in developing the project

  3. Development of a test system for high level liquid waste partitioning

    Directory of Open Access Journals (Sweden)

    Duan Wu H.

    2015-01-01

    Full Text Available The partitioning and transmutation strategy has increasingly attracted interest for the safe treatment and disposal of high level liquid waste, in which the partitioning of high level liquid waste is one of the critical technical issues. An improved total partitioning process, including a tri-alkylphosphine oxide process for the removal of actinides, a crown ether strontium extraction process for the removal of strontium, and a calixcrown ether cesium extraction process for the removal of cesium, has been developed to treat Chinese high level liquid waste. A test system containing 72-stage 10-mm-diam annular centrifugal contactors, a remote sampling system, a rotor speed acquisition-monitoring system, a feeding system, and a video camera-surveillance system was successfully developed to carry out the hot test for verifying the improved total partitioning process. The test system has been successfully used in a 160 hour hot test using genuine high level liquid waste. During the hot test, the test system was stable, which demonstrated it was reliable for the hot test of the high level liquid waste partitioning.

  4. Methods of Disposing Of High-Level Radioactive Waste: A Review

    International Nuclear Information System (INIS)

    Abumurade, K.

    2002-01-01

    High level nuclear waste from both commercial reactors and defense industry presents a difficult problem to the scientific community as well as the public. The solutions to this problem is still debatable both technically and ethically. There are few methods proposed for disposing of high level waste. Each method has its own advantages and disadvantages. However, the very deep underground geologic repository is the best choice for disposing of high-level radioactive wastes. The cost benefit equation of nuclear power production and its waste is discussed. However, the public should be educated about this matter to minimize the gap between them and the nuclear power community including scientists industry, and governments. (Author) 15 refs., 4 tabs., 1 fig

  5. Extract of mangosteen increases high density lipoprotein levels in rats fed high lipid

    Directory of Open Access Journals (Sweden)

    Dwi Laksono Adiputro

    2013-04-01

    Full Text Available Background In cardiovascular medicine, Garcinia mangostana has been used as an antioxidant to inhibit oxidation of low density lipoproteins and as an antiobesity agent. The effect of Garcinia mangostana on hyperlipidemia is unknown. The aim of this study was to evaluate the effect of an ethanolic extract of Garcinia mangostana pericarp on lipid profile in rats fed a high lipid diet. Methods A total of 40 rats were divided into five groups control, high lipid diet, and high lipid diet + ethanolic extract of Garcinia mangostana pericarp at dosages of 200, 400, and 800 mg/kg body weight. The control group received a standard diet for 60 days. The high lipid diet group received standard diet plus egg yolk, goat fat, cholic acid, and pig fat for 60 days with or without ethanolic extract of Garcinia mangostana pericarp by the oral route. After 60 days, rats were anesthesized with ether for collection of blood by cardiac puncture. Analysis of blood lipid profile comprised colorimetric determination of cholesterol, triglyceride, low density lipoprotein (LDL, and high density lipoprotein (HDL. Results From the results of one-way ANOVA it was concluded that there were significant between-group differences in cholesterol, trygliceride, LDL, and HDL levels (p=0.000. Ethanolic extract of Garcinia mangostana pericarp significantly decreased cholesterol, trygliceride, and LDL levels, starting at 400 mg/kg body weight (p=0.000. Ethanolic extract of Garcinia mangostana pericarp significantly increased HDL level starting at 200 mg/kg body weight (p=0.000. Conclusion Ethanolic extract of Garcinia mangostana pericarp has a beneficial effect on lipid profile in rats on a high lipid diet.

  6. Extract of mangosteen increases high density lipoprotein levels in rats fed high lipid

    Directory of Open Access Journals (Sweden)

    Dwi Laksono Adiputro

    2015-12-01

    Full Text Available BACKGROUND In cardiovascular medicine, Garcinia mangostana has been used as an antioxidant to inhibit oxidation of low density lipoproteins and as an antiobesity agent. The effect of Garcinia mangostana on hyperlipidemia is unknown. The aim of this study was to evaluate the effect of an ethanolic extract of Garcinia mangostana pericarp on lipid profile in rats fed a high lipid diet. METHODS A total of 40 rats were divided into five groups control, high lipid diet, and high lipid diet + ethanolic extract of Garcinia mangostana pericarp at dosages of 200, 400, and 800 mg/kg body weight. The control group received a standard diet for 60 days. The high lipid diet group received standard diet plus egg yolk, goat fat, cholic acid, and pig fat for 60 days with or without ethanolic extract of Garcinia mangostana pericarp by the oral route. After 60 days, rats were anesthesized with ether for collection of blood by cardiac puncture. Analysis of blood lipid profile comprised colorimetric determination of cholesterol, triglyceride, low density lipoprotein (LDL, and high density lipoprotein (HDL. RESULTS From the results of one-way ANOVA it was concluded that there were significant between-group differences in cholesterol, trygliceride, LDL, and HDL levels (p=0.000. Ethanolic extract of Garcinia mangostana pericarp significantly decreased cholesterol, trygliceride, and LDL levels, starting at 400 mg/kg body weight (p=0.000. Ethanolic extract of Garcinia mangostana pericarp significantly increased HDL level starting at 200 mg/kg body weight (p=0.000. CONCLUSION Ethanolic extract of Garcinia mangostana pericarp has a beneficial effect on lipid profile in rats on a high lipid diet.

  7. US program for the immobilization of high-level nuclear wastes

    International Nuclear Information System (INIS)

    Crandall, J.L.

    1979-01-01

    A program has been developed for long-term management of high-level nuclear waste. The Savannah River Operations Office of the US Department of Energy is acting as the lead office for this program with technical advice from the E.I. du Pont de Nemours and Company. The purpose of the long-term program is to immobilize the DOE high-level waste in forms that act as highly efficient barriers against radionuclide release to the disposal site and to provide technology for similar treatment of commercial high-level waste in case reprocessing of commercial nuclear fuels is ever resumed. Descriptions of existing DOE and commercial wastes, program strategy, program expenditures, development of waste forms, evaluation and selection of waste forms, regulatory aspects of waste form selection, project schedules, and cost estimates for immobilization facilities are discussed

  8. Non-targeted analysis of unexpected food contaminants using LC-HRMS.

    Science.gov (United States)

    Kunzelmann, Marco; Winter, Martin; Åberg, Magnus; Hellenäs, Karl-Erik; Rosén, Johan

    2018-03-29

    A non-target analysis method for unexpected contaminants in food is described. Many current methods referred to as "non-target" are capable of detecting hundreds or even thousands of contaminants. However, they will typically still miss all other possible contaminants. Instead, a metabolomics approach might be used to obtain "true non-target" analysis. In the present work, such a method was optimized for improved detection capability at low concentrations. The method was evaluated using 19 chemically diverse model compounds spiked into milk samples to mimic unknown contamination. Other milk samples were used as reference samples. All samples were analyzed with UHPLC-TOF-MS (ultra-high-performance liquid chromatography time-of-flight mass spectrometry), using reversed-phase chromatography and electrospray ionization in positive mode. Data evaluation was performed by the software TracMass 2. No target lists of specific compounds were used to search for the contaminants. Instead, the software was used to sort out all features only occurring in the spiked sample data, i.e., the workflow resembled a metabolomics approach. Procedures for chemical identification of peaks were outside the scope of the study. Method, study design, and settings in the software were optimized to minimize manual evaluation and faulty or irrelevant hits and to maximize hit rate of the spiked compounds. A practical detection limit was established at 25 μg/kg. At this concentration, most compounds (17 out of 19) were detected as intact precursor ions, as fragments or as adducts. Only 2 irrelevant hits, probably natural compounds, were obtained. Limitations and possible practical use of the approach are discussed.

  9. Molecular Phylogeny of the Astrophorida (Porifera, Demospongiae p) Reveals an Unexpected High Level of Spicule Homoplasy

    Science.gov (United States)

    Cárdenas, Paco; Xavier, Joana R.; Reveillaud, Julie; Schander, Christoffer; Rapp, Hans Tore

    2011-01-01

    Background The Astrophorida (Porifera, Demospongiae p) is geographically and bathymetrically widely distributed. Systema Porifera currently includes five families in this order: Ancorinidae, Calthropellidae, Geodiidae, Pachastrellidae and Thrombidae. To date, molecular phylogenetic studies including Astrophorida species are scarce and offer limited sampling. Phylogenetic relationships within this order are therefore for the most part unknown and hypotheses based on morphology largely untested. Astrophorida taxa have very diverse spicule sets that make them a model of choice to investigate spicule evolution. Methodology/Principal Findings With a sampling of 153 specimens (9 families, 29 genera, 89 species) covering the deep- and shallow-waters worldwide, this work presents the first comprehensive molecular phylogeny of the Astrophorida, using a cytochrome c oxidase subunit I (COI) gene partial sequence and the 5′ end terminal part of the 28S rDNA gene (C1-D2 domains). The resulting tree suggested that i) the Astrophorida included some lithistid families and some Alectonidae species, ii) the sub-orders Euastrophorida and Streptosclerophorida were both polyphyletic, iii) the Geodiidae, the Ancorinidae and the Pachastrellidae were not monophyletic, iv) the Calthropellidae was part of the Geodiidae clade (Calthropella at least), and finally that v) many genera were polyphyletic (Ecionemia, Erylus, Poecillastra, Penares, Rhabdastrella, Stelletta and Vulcanella). Conclusion The Astrophorida is a larger order than previously considered, comprising ca. 820 species. Based on these results, we propose new classifications for the Astrophorida using both the classical rank-based nomenclature (i.e., Linnaean classification) and the phylogenetic nomenclature following the PhyloCode, independent of taxonomic rank. A key to the Astrophorida families, sub-families and genera incertae sedis is also included. Incongruences between our molecular tree and the current classification can be explained by the banality of convergent evolution and secondary loss in spicule evolution. These processes have taken place many times, in all the major clades, for megascleres and microscleres. PMID:21494664

  10. Safe sleep practices in a New Zealand community and development of a Sudden Unexpected Death in Infancy (SUDI) risk assessment instrument.

    Science.gov (United States)

    Galland, Barbara C; Gray, Andrew; Sayers, Rachel M; Heath, Anne-Louise M; Lawrence, Julie; Taylor, Rachael; Taylor, Barry J

    2014-10-13

    Interventions to prevent sudden unexpected death in infancy (SUDI) have generally been population wide interventions instituted after case-control studies identified specific childcare practices associated with sudden death. While successful overall, in New Zealand (NZ), the rates are still relatively high by international comparison. This study aims to describe childcare practices related to SUDI prevention messages in a New Zealand community, and to develop and explore the utility of a risk assessment instrument based on international guidelines and evidence. Prospective longitudinal study of 209 infants recruited antenatally. Participant characteristics and infant care data were collected by questionnaire at: baseline (third trimester), and monthly from infant age 3 weeks through 23 weeks. Published meta-analyses data were used to estimate individual risk ratios for 6 important SUDI risk factors which, when combined, yielded a "SUDI risk score". Most infants were at low risk for SUDI with 72% at the lowest or slightly elevated risk (combined risk ratio ≤1.5). There was a high prevalence of the safe practices: supine sleeping (86-89% over 3-19 weeks), mother not smoking (90-92% over 3-19 weeks), and not bed sharing at a young age (87% at 3 weeks). Five independent predictors of a high SUDI risk score were: higher parity (P =0.028), younger age (P =0.030), not working or caring for other children antenatally (P =0.031), higher depression scores antenatally (P =0.036), and lower education (P =0.042). Groups within the community identified as priorities for education about safe sleep practices beyond standard care are mothers who are young, have high parity, low educational levels, and have symptoms of depression antenatally. These findings emphasize the importance of addressing maternal depression as a modifiable risk factor in pregnancy.

  11. Reachability Trees for High-level Petri Nets

    DEFF Research Database (Denmark)

    Jensen, Kurt; Jensen, Arne M.; Jepsen, Leif Obel

    1986-01-01

    the necessary analysis methods. In other papers it is shown how to generalize the concept of place- and transition invariants from place/transition nets to high-level Petri nets. Our present paper contributes to this with a generalization of reachability trees, which is one of the other important analysis...

  12. Chromosome Aberration on High Level Background Natural Radiation Areas

    International Nuclear Information System (INIS)

    Yanti-Lusiyanti; Zubaidah-Alatas

    2001-01-01

    When the body is irradiated, all cells can suffer cytogenetic damage that can be seen as structural damage of chromosome in the lymphocytes. People no matter where they live in world are exposed to background radiation from natural sources both internal and external such as cosmic radiation, terrestrial radiation, cosmogenic radiation radon and thoron. Level of area natural ionizing radiation is varies depending on the altitude, the soil or rock conditions, particular food chains and the building materials and construction features. Level of normal areas of background exposure is annual effective dose 2.4 mSv and the high level areas of background exposure 20 mSv. This paper discuses the frequency of aberration chromosome especially dysenteries in several countries having high level radiation background. It seems that frequency of chromosome aberrations increase, generally with the increase of age of the people and the accumulated dose received. (author)

  13. Anticipating Serendipity. Preparing for the Unexpected.

    Directory of Open Access Journals (Sweden)

    Marlowe Thomas J.

    2014-08-01

    Full Text Available Serendipity—using "fortunate accidents" for learning or discovery—is a valued if too infrequent route to progress. Although serendipity cannot be scheduled or relied upon, one can develop skills, flexibility and habits of mind that make the recognition and incorporation of serendipitous discoveries more likely. This paper overviews at a high level a program of activities and concepts aimed at preparing modern professionals and communities to leverage the fortunate occurrences they encounter.

  14. Design features of a full-scale high-level waste vitrification system

    International Nuclear Information System (INIS)

    Siemens, D.H.; Bonner, W.F.

    1976-08-01

    A system has been designed and is currently under construction for vitrification of commercial high-level waste. The process consists of a spray calciner coupled to an in-can melter. Due to the high radiation levels expected, this equipment is designed for totally remote operation and maintenance. The in-cell arrangement of this equipment has been developed cooperatively with a nuclear fuel reprocessor. The system will be demonstrated both full scale with nonradioactive simulated waste and pilot scale with actual high-level waste

  15. Assessment of studies and researches on warehousing - High-level and intermediate-level-long-lived radioactive wastes - December 2012

    International Nuclear Information System (INIS)

    2013-01-01

    This large report first presents the approach adopted for the study and research on the warehousing of high-level and intermediate-level-long-lived radioactive wastes. It outlines how reversible storage and warehousing are complementary, discusses the lessons learned from researches performed by the CEA on long duration warehousing, presents the framework of studies and researches performed since 2006, and presents the scientific and technical content of studies and researches (warehousing need analysis, search for technical options providing complementarity with storage, extension or creation of warehousing installations). The second part addresses high-level and intermediate-level-long-lived radioactive waste parcels, indicates their origins and quantities. The third part proposes an analysis of warehousing capacities: existing capacities, French industrial experience in waste parcel warehousing, foreign experience in waste warehousing. The fourth part addresses reversible storage in deep geological formation: storage safety functions, storage reversibility, storage parcels, storage architecture, chronicle draft. The fifth part proposes an inventory of warehousing needs in terms of additional capacities for the both types of wastes (high-level, and intermediate-level-long-lived), and discusses warehousing functionalities and safety objectives. The sixth and seventh parts propose a detailed overview of design options for warehousing installations, respectively for high-level and for intermediate-level-long-lived waste parcels: main technical issues, feasibility studies of different concepts or architecture shapes, results of previous studies and introduction to studies performed since 2011, possible evolutions of the HA1, HA2 and MAVL concepts. The eighth chapter reports a phenomenological analysis of warehousing and the optimisation of material selection and construction arrangements. The last part discusses the application of researches to the extension of the

  16. Management of high level radioactive waste

    International Nuclear Information System (INIS)

    Redon, A.; Mamelle, J.; Chambon, M.

    1977-01-01

    The world wide needs in reprocessing will reach the value of 10.000 t/y of irradiated fuels, in the mid of the 80's. Several countries will have planned, in their nuclear programme, the construction of reprocessing plants with a 1500 t/y capacity, corresponding to 50.000 MWe installed. At such a level, the solidification of the radioactive waste will become imperative. For this reason, all efforts, in France, have been directed towards the realization of industrial plants able of solidifying the fission products as a glassy material. The advantages of this decision, and the reasons for it are presented. The continuing development work, and the conditions and methods of storing the high-level wastes prior to solidification, and of the interim storage (for thermal decay) and the ultimate disposal after solidification are described [fr

  17. Development of melt compositions for sulphate bearing high level waste

    International Nuclear Information System (INIS)

    Jahagirdar, P.B.; Wattal, P.K.

    1997-09-01

    The report deals with the development and characterization of vitreous matrices for sulphate bearing high level waste. Studies were conducted in sodium borosilicate and lead borosilicate systems with the introduction of CaO, BaO, MgO etc. Lead borosilicate system was found to be compatible with sulphate bearing high level wastes. Detailed product evaluation carried on selected formulations is also described. (author)

  18. Decision Document for Heat Removal from High-Level Waste Tanks

    International Nuclear Information System (INIS)

    WILLIS, W.L.

    2000-01-01

    This document establishes the combination of design and operational configurations that will be used to provide heat removal from high-level waste tanks during Phase 1 waste feed delivery to prevent the waste temperature from exceeding tank safety requirement limits. The chosen method--to use the primary and annulus ventilation systems to remove heat from the high-level waste tanks--is documented herein

  19. Future directions of defense programs high-level waste technology programs

    International Nuclear Information System (INIS)

    Chee, T.C.; Shupe, M.W.; Turner, D.A.; Campbell, M.H.

    1987-01-01

    The Department of Energy has been managing high-level waste from the production of nuclear materials for defense activities over the last forty years. An objective for the Defense Waste and Transportation Management program is to develop technology which ensures the safe, permanent disposal of all defense radioactive wastes. Technology programs are underway to address the long-term strategy for permanent disposal of high-level waste generated at each Department of Energy site. Technology is being developed for assessing the hazards, environmental impacts, and costs of each long-term disposal alternative for selection and implementation. This paper addresses key technology development areas, and consideration of recent regulatory requirements associated with the long-term management of defense radioactive high-level waste

  20. High-level radioactive waste disposal type and theoretical analyses

    International Nuclear Information System (INIS)

    Lu Yingfa; Wu Yanchun; Luo Xianqi; Cui Yujun

    2006-01-01

    Study of high-level radioactive waste disposal is necessary for the nuclear electrical development; the determination of nuclear waste depository type is one of importance safety. Based on the high-level radioactive disposal type, the relative research subjects are proposed, then the fundamental research characteristics of nuclear waste disposition, for instance: mechanical and hydraulic properties of rock mass, saturated and unsaturated seepage, chemical behaviors, behavior of special soil, and gas behavior, etc. are introduced, the relative coupling equations are suggested, and a one dimensional result is proposed. (authors)

  1. A new unexpected feature of superdeformed nuclei: strange degeneracies and their origin

    International Nuclear Information System (INIS)

    Dudek, J.

    1990-01-01

    Unexpected similarities between the superdeformed bands found recently in many nuclei of the mass A ∼ 150 and A ∼ 190 regions and the physical sense of this discovery are discussed. These similarities manifest themselves through the existence of nearly identical sequences of transitions belonging to two neighboring nuclei, and by now numerous nuclear pairs manifesting this feature have been found. The underlying microscopic mechanism is traced back to two independent effects: a readjustment of nuclear deformation diminishing the role of alignment of the least bound nucleus, and, the pseudospin symmetry, responsible for an approximate decoupling of the orbital and the intrinsic (pseudo) spin-degrees of freedom. 9 figs

  2. The ATLAS high level trigger region of interest builder

    International Nuclear Information System (INIS)

    Blair, R.; Dawson, J.; Drake, G.; Haberichter, W.; Schlereth, J.; Zhang, J.; Ermoline, Y.; Pope, B.; Aboline, M.; High Energy Physics; Michigan State Univ.

    2008-01-01

    This article describes the design, testing and production of the ATLAS Region of Interest Builder (RoIB). This device acts as an interface between the Level 1 trigger and the high level trigger (HLT) farm for the ATLAS LHC detector. It distributes all of the Level 1 data for a subset of events to a small number of (16 or less) individual commodity processors. These processors in turn provide this information to the HLT. This allows the HLT to use the Level 1 information to narrow data requests to areas of the detector where Level 1 has identified interesting objects

  3. Some legal aspects on high level radioactive waste disposal in Japan

    International Nuclear Information System (INIS)

    Tanabe, Tomoyuki

    1997-01-01

    In Japan, it is considered to be an urgent problem to prepare the system for the research and execution of high level radioactive waste disposal. Under what regulation scheme the disposal should be done has not been sufficiently examined. In this research, the examination was carried out on the legal aspects of high level radioactive waste disposal as follows. First, the current legislation on the disposal in Japan was analyzed, and it was made clear that high level radioactive waste disposal has not been stipulated clearly. Next, on the legal choices which are conceivable on the way the legislation for high level radioactive waste disposal should be, from the aspects of applying the law on regulating nuclear reactors and others, applying the law on nuclear power damage reparation, and industrialization by changing the government ordinances, those were arranged in six choices, and the examination was carried out for each choice from the viewpoints of the relation with the base stipulation for waste-burying business, the speciality of high level radioactive waste disposal as compared with other actions of nuclear power business, the coordination with existing nuclear power of nuclear power business, the coordination with existing nuclear power law system and the formation of national consensus. In this research, it was shown that the execution of high level radioactive waste disposal as the business based on the separate legislation is the realistic choice. (K.I.)

  4. Electrocardiographic features of sudden unexpected death in epilepsy.

    Science.gov (United States)

    Chyou, Janice Y; Friedman, Daniel; Cerrone, Marina; Slater, William; Guo, Yu; Taupin, Daniel; O'Rourke, Sean; Priori, Silvia G; Devinsky, Orrin

    2016-07-01

    Sudden unexpected death in epilepsy (SUDEP) is the most common cause of epilepsy-related mortality. We hypothesized that electrocardiography (ECG) features may distinguish SUDEP cases from living subjects with epilepsy. Using a matched case-control design, we compared ECG studies of 12 consecutive cases of SUDEP over 10 years and 22 epilepsy controls matched for age, sex, epilepsy type (focal, generalized, or unknown/mixed type), concomitant antiepileptic, and psychotropic drug classes. Conduction intervals and prevalence of abnormal ventricular conduction diagnosis (QRS ≥110 msec), abnormal ventricular conduction pattern (QRS <110 msec, morphology of incomplete right or left bundle branch block or intraventricular conduction delay), early repolarization, and features of inherited cardiac channelopathies were assessed. Abnormal ventricular conduction diagnosis and pattern distinguished SUDEP cases from matched controls. Abnormal ventricular conduction diagnosis was present in two cases and no controls. Abnormal ventricular conduction pattern was more common in cases than controls (58% vs. 18%, p = 0.04). Early repolarization was similarly prevalent in cases and controls, but the overall prevalence exceeded that of published community-based cohorts. Wiley Periodicals, Inc. © 2016 International League Against Epilepsy.

  5. CMS High Level Trigger Timing Measurements

    International Nuclear Information System (INIS)

    Richardson, Clint

    2015-01-01

    The two-level trigger system employed by CMS consists of the Level 1 (L1) Trigger, which is implemented using custom-built electronics, and the High Level Trigger (HLT), a farm of commercial CPUs running a streamlined version of the offline CMS reconstruction software. The operational L1 output rate of 100 kHz, together with the number of CPUs in the HLT farm, imposes a fundamental constraint on the amount of time available for the HLT to process events. Exceeding this limit impacts the experiment's ability to collect data efficiently. Hence, there is a critical need to characterize the performance of the HLT farm as well as the algorithms run prior to start up in order to ensure optimal data taking. Additional complications arise from the fact that the HLT farm consists of multiple generations of hardware and there can be subtleties in machine performance. We present our methods of measuring the timing performance of the CMS HLT, including the challenges of making such measurements. Results for the performance of various Intel Xeon architectures from 2009-2014 and different data taking scenarios are also presented. (paper)

  6. Experiences in messaging middle-ware for high-level control applications

    International Nuclear Information System (INIS)

    Wanga, N.; Shasharina, S.; Matykiewicz, J.; Rooparani Pundaleeka

    2012-01-01

    Existing high-level applications in accelerator control and modeling systems leverage many different languages, tools and frameworks that do not inter-operate with one another. As a result, the accelerator control community is moving toward the proven Service-Oriented Architecture (SOA) approach to address the inter-operability challenges among heterogeneous high-level application modules. Such SOA approach enables developers to package various control subsystems and activities into 'services' with well-defined 'interfaces' and make leveraging heterogeneous high-level applications via flexible composition possible. Examples of such applications include presentation panel clients based on Control System Studio (CSS) and middle-layer applications such as model/data servers. This paper presents our experiences in developing a demonstrative high-level application environment using emerging messaging middle-ware standards. In particular, we utilize new features in EPICS v4 and other emerging standards such as Data Distribution Service (DDS) and Extensible Type Interface by the Object Management Group. We first briefly review examples we developed previously. We then present our current effort in integrating DDS into such a SOA environment for control systems. Specifically, we illustrate how we are integrating DDS into CSS and develop a Python DDS mapping. (authors)

  7. Ultrasonic level sensors for liquids under high pressure

    Science.gov (United States)

    Zuckerwar, A. J.; Mazel, D. S.; Hodges, D. Y.

    1986-01-01

    An ultrasonic level sensor of novel design continuously measures the level of a liquid subjected to a high pressure (up to about 40 MPa), as is sometimes required for the effective transfer of the liquid. The sensor operates as a composite resonator fabricated from a standard high-pressure plug. A flat-bottom hole is machined into the plug along its center line. An ultrasonic transducer is bonded rigidly to the interior surface of the bottom wall, while the exterior surface is in contact with the liquid. Although the bottom wall is designed to satisfy the pressure code, it is still sufficiently thin to permit ready excitation of the axisymmetric plate modes of vibration. The liquid level is measured by a conventional pulse-echo technique. A prototype sensor was tested successfully in a 2300-l water vessel at pressures up to about 37 MPa. A spectral analysis of the transmitted pulse reveals that the flexural, extensional, thickness-shear, and radial plate modes are excited into vibration, but none of these appears to be significantly affected by the pressurization of the liquid.

  8. Availability verification of information for human system interface in automatic SG level control using activity diagram

    Energy Technology Data Exchange (ETDEWEB)

    Nuraslinda, Anuar; Kim, Dong Young; Kim, Jong Hyun [KEPCO International Nuclear Graduate School, Uljugun (Korea, Republic of)

    2012-10-15

    Steam Generator (SG) level control system in OPR 1000 is one of representative automatic systems that falls under the Supervisory Control level in Endsley's taxonomy. Supervisory control of automated systems is classified as a form of out of the loop (OOTL) performance due to passive involvement in the systems operation, which could lead to loss of situation awareness (SA). There was a reported event, which was caused by inadequate human automation communication that contributed to an unexpected reactor trip in July 2005. A high SG level trip occurred in Yeonggwang (YGN) Unit 6 Nuclear Power Plant (NPP) due to human operator failure to recognize the need to change the control mode of the economizer valve controller (EVC) to manual mode during swap over (the transition from low power mode to high power mode) after the loss of offsite power (LOOP) event was recovered. This paper models the human system interaction in NPP SG level control system using Unified Modeling Language (UML) Activity Diagram. Then, it identifies the missing information for operators in the OPR1000 Main Control Room (MCR) and suggests some means of improving the human system interaction.

  9. Availability verification of information for human system interface in automatic SG level control using activity diagram

    International Nuclear Information System (INIS)

    Nuraslinda, Anuar; Kim, Dong Young; Kim, Jong Hyun

    2012-01-01

    Steam Generator (SG) level control system in OPR 1000 is one of representative automatic systems that falls under the Supervisory Control level in Endsley's taxonomy. Supervisory control of automated systems is classified as a form of out of the loop (OOTL) performance due to passive involvement in the systems operation, which could lead to loss of situation awareness (SA). There was a reported event, which was caused by inadequate human automation communication that contributed to an unexpected reactor trip in July 2005. A high SG level trip occurred in Yeonggwang (YGN) Unit 6 Nuclear Power Plant (NPP) due to human operator failure to recognize the need to change the control mode of the economizer valve controller (EVC) to manual mode during swap over (the transition from low power mode to high power mode) after the loss of offsite power (LOOP) event was recovered. This paper models the human system interaction in NPP SG level control system using Unified Modeling Language (UML) Activity Diagram. Then, it identifies the missing information for operators in the OPR1000 Main Control Room (MCR) and suggests some means of improving the human system interaction

  10. Standards for high level waste disposal: A sustainability perspective

    International Nuclear Information System (INIS)

    Dougherty, W.W.; Powers, V.; Johnson, F.X.; Cornland, D.

    1999-01-01

    Spent reactor fuel from commercial power stations contains high levels of plutonium, other fissionable actinides, and fission products, all of which pose serious challenges for permanent disposal because of the very long half-lives of some isotopes. The 'nuclear nations' have agreed on the use of permanent geologic repositories for the ultimate disposal of high-level nuclear waste. However, it is premature to claim that a geologic repository offers permanent isolation from the biosphere, given high levels of uncertainty, nascent risk assessment frameworks for the time periods considered, and serious intergenerational equity issues. Many have argued for a broader consideration of disposal options that include extended monitored retrievable storage and accelerator-driven transmutation of wastes. In this paper we discuss and compare these three options relative to standards that emerge from the application of sustainable development principles, namely long-lasting technical viability, intergenerational equity, rational resource allocation, and rights of future intervention. We conclude that in order to maximise the autonomy of future generations, it is imperative to leave future options more open than does permanent disposal

  11. Neural Networks Mediating High-Level Mentalizing in Patients With Right Cerebral Hemispheric Gliomas

    Directory of Open Access Journals (Sweden)

    Riho Nakajima

    2018-03-01

    Full Text Available Mentalizing is the ability to understand others’ mental state through external cues. It consists of two networks, namely low-level and high-level metalizing. Although it is an essential function in our daily social life, surgical resection of right cerebral hemisphere disturbs mentalizing processing with high possibility. In the past, little was known about the white matter related to high-level mentalizing, and the conservation of high-level mentalizing during surgery has not been a focus of attention. Therefore, the main purpose of this study was to examine the neural networks underlying high-level mentalizing and then, secondarily, investigate the usefulness of awake surgery in preserving the mentalizing network. A total of 20 patients with glioma localized in the right hemisphere who underwent awake surgery participated in this study. All patients were assigned to two groups: with or without intraoperative assessment of high-level mentalizing. Their high-level mentalizing abilities were assessed before surgery and 1 week and 3 months after surgery. At 3 months after surgery, only patients who received the intraoperative high-level mentalizing test showed the same score as normal healthy volunteers. The tract-based lesion symptom analysis was performed to confirm the severity of damage of associated fibers and high-level mentalizing accuracy. This analysis revealed the superior longitudinal fascicles (SLF III and fronto-striatal tract (FST to be associated with high-level mentalizing processing. Moreover, the voxel-based lesion symptom analysis demonstrated that resection of orbito-frontal cortex (OFC causes persistent mentalizing dysfunction. Our study indicates that damage of the OFC and structural connectivity of the SLF and FST causes the disorder of mentalizing after surgery, and assessing high-level mentalizing during surgery may be useful to preserve these pathways.

  12. Proposed classification scheme for high-level and other radioactive wastes

    International Nuclear Information System (INIS)

    Kocher, D.C.; Croff, A.G.

    1986-01-01

    The Nuclear Waste Policy Act (NWPA) of 1982 defines high-level radioactive waste (HLW) as: (A) the highly radioactive material resulting from the reprocessing of spent nuclear fuel....that contains fission products in sufficient concentrations; and (B) other highly radioactive material that the Commission....determines....requires permanent isolation. This paper presents a generally applicable quantitative definition of HLW that addresses the description in paragraph (B). The approach also results in definitions of other waste classes, i.e., transuranic (TRU) and low-level waste (LLW). A basic waste classification scheme results from the quantitative definitions

  13. DUACS: Toward High Resolution Sea Level Products

    Science.gov (United States)

    Faugere, Y.; Gerald, D.; Ubelmann, C.; Claire, D.; Pujol, M. I.; Antoine, D.; Desjonqueres, J. D.; Picot, N.

    2016-12-01

    The DUACS system produces, as part of the CNES/SALP project, and the Copernicus Marine Environment and Monitoring Service, high quality multimission altimetry Sea Level products for oceanographic applications, climate forecasting centers, geophysic and biology communities... These products consist in directly usable and easy to manipulate Level 3 (along-track cross-calibrated SLA) and Level 4 products (multiple sensors merged as maps or time series) and are available in global and regional version (Mediterranean Sea, Arctic, European Shelves …).The quality of the products is today limited by the altimeter technology "Low Resolution Mode" (LRM), and the lack of available observations. The launch of 2 new satellites in 2016, Jason-3 and Sentinel-3A, opens new perspectives. Using the global Synthetic Aperture Radar mode (SARM) coverage of S3A and optimizing the LRM altimeter processing (retracking, editing, ...) will allow us to fully exploit the fine-scale content of the altimetric missions. Thanks to this increase of real time altimetry observations we will also be able to improve Level-4 products by combining these new Level-3 products and new mapping methodology, such as dynamic interpolation. Finally these improvements will benefit to downstream products : geostrophic currents, Lagrangian products, eddy atlas… Overcoming all these challenges will provide major upgrades of Sea Level products to better fulfill user needs.

  14. Key scientific challenges in geological disposal of high level radioactive waste

    International Nuclear Information System (INIS)

    Wang Ju

    2007-01-01

    The geological disposal of high radioactive waste is a challenging task facing the scientific and technical world. This paper introduces the latest progress of high level radioactive disposal programs in the latest progress of high level radioactive disposal programs in the world, and discusses the following key scientific challenges: (1) precise prediction of the evolution of a repository site; (2) characteristics of deep geological environment; (3) behaviour of deep rock mass, groundwater and engineering material under coupled con-ditions (intermediate to high temperature, geostress, hydraulic, chemical, biological and radiation process, etc); (4) geo-chemical behaviour of transuranic radionuclides with low concentration and its migration with groundwater; and (5) safety assessment of disposal system. Several large-scale research projects and several hot topics related with high-level waste disposal are also introduced. (authors)

  15. The effects of acute foot shock stress on empathy levels in rats.

    Science.gov (United States)

    Karakilic, Aslı; Kizildag, Servet; Kandis, Sevim; Guvendi, Guven; Koc, Basar; Camsari, Gamze B; Camsari, Ulas M; Ates, Mehmet; Arda, Sevil Gonenc; Uysal, Nazan

    2018-09-03

    Empathy defined as the ability to understand and the share the feelings, thoughts, and attitudes of another, is an important skill in survival and reproduction. Among many factors that affect empathy include psychological stress, anxiety states. The aim of this study was to investigate the impact of acute psychological stress on empathic behavior and its association with oxytocin and vasopressin levels in amygdala and prefrontal cortex. Rats were subjected to 0.2 mA (low) and 1.6 mA (high) intensity of foot shock stress for duration of 20 min. Empathic behavior was found to be improved as a response to low intensity stress, but not to high intensity stress. As a response to lower intensity stress, vasopressin was increased in prefrontal cortex and amygdala; oxytocin was increased in only prefrontal cortex, and corticosterone levels increased in general. Anxiety indicators did not change in low intensity stress group yet; high intensity stress group demonstrated a lesser degree of anxiety response. High intensity stress group stayed unexpectedly more active in middle area of elevated plus maze test equipment, which may support impaired executive decision making abilities in the setting of high anxiety states. Further research is needed to investigate gender effects, the role of dopaminergic system and other stress related pathways in acute stress. Copyright © 2018 Elsevier B.V. All rights reserved.

  16. Unexpected Diagnosis of Cerebral Toxoplasmosis by 16S and D2 Large-Subunit Ribosomal DNA PCR and Sequencing

    DEFF Research Database (Denmark)

    Kruse, Alexandra Yasmin Collin; Kvich, Lasse Andersson; Eickhardt-Dalbøge, Steffen Robert

    2015-01-01

    The protozoan parasite Toxoplasma gondii causes severe opportunistic infections. Here, we report an unexpected diagnosis of cerebral toxoplasmosis. T. gondii was diagnosed by 16S and D2 large-subunit (LSU) ribosomal DNA (rDNA) sequencing of a cerebral biopsy specimen and confirmed by T. gondii...

  17. Parity dependence of the nuclear level density at high excitation

    International Nuclear Information System (INIS)

    Rao, B.V.; Agrawal, H.M.

    1995-01-01

    The basic underlying assumption ρ(l+1, J)=ρ(l, J) in the level density function ρ(U, J, π) has been checked on the basis of high quality data available on individual resonance parameters (E 0 , Γ n , J π ) for s- and p-wave neutrons in contrast to the earlier analysis where information about p-wave resonance parameters was meagre. The missing level estimator based on the partial integration over a Porter-Thomas distribution of neutron reduced widths and the Dyson-Mehta Δ 3 statistic for the level spacing have been used to ascertain that the s- and p-wave resonance level spacings D(0) and D(1) are not in error because of spurious and missing levels. The present work does not validate the tacit assumption ρ(l+1, J)=ρ(l, J) and confirms that the level density depends upon parity at high excitation. The possible implications of the parity dependence of the level density on the results of statistical model calculations of nuclear reaction cross sections as well as on pre-compound emission have been emphasized. (orig.)

  18. Unexpected low thermal conductivity and large power factor in Dirac semimetal Cd3As2

    Science.gov (United States)

    Cheng, Zhang; Tong, Zhou; Sihang, Liang; Junzhi, Cao; Xiang, Yuan; Yanwen, Liu; Yao, Shen; Qisi, Wang; Jun, Zhao; Zhongqin, Yang; Faxian, Xiu

    2016-01-01

    Thermoelectrics has long been considered as a promising way of power generation for the next decades. So far, extensive efforts have been devoted to the search of ideal thermoelectric materials, which require both high electrical conductivity and low thermal conductivity. Recently, the emerging Dirac semimetal Cd3As2, a three-dimensional analogue of graphene, has been reported to host ultra-high mobility and good electrical conductivity as metals. Here, we report the observation of unexpected low thermal conductivity in Cd3As2, one order of magnitude lower than the conventional metals or semimetals with a similar electrical conductivity, despite the semimetal band structure and high electron mobility. The power factor also reaches a large value of 1.58 mW·m-1·K-2 at room temperature and remains non-saturated up to 400 K. Corroborating with the first-principles calculations, we find that the thermoelectric performance can be well-modulated by the carrier concentration in a wide range. This work demonstrates the Dirac semimetal Cd3As2 as a potential candidate of thermoelectric materials. Project supported by the National Young 1000 Talent Plan China, the Pujiang Talent Plan in Shanghai, China, the National Natural Science Foundation of China (Grant Nos. 61322407 and 11474058), the Fund for Fostering Talents in Basic Science of the National Natural Science Foundation of China (Grant No. J1103204), and the National Basic Research Program of China (Grant No. 2011CB921803).

  19. Should I Stay or Should I Go? Attentional Disengagement from Visually Unique and Unexpected Items at Fixation

    Science.gov (United States)

    Brockmole, James R.; Boot, Walter R.

    2009-01-01

    Distinctive aspects of a scene can capture attention even when they are irrelevant to one's goals. The authors address whether visually unique, unexpected, but task-irrelevant features also tend to hold attention. Observers searched through displays in which the color of each item was irrelevant. At the start of search, all objects changed color.…

  20. Frustration stress (unexpected loss of alternative reinforcement) increases opioid self-administration in a model of recovery.

    Science.gov (United States)

    Ginsburg, Brett C; Lamb, R J

    2018-01-01

    Engaging in alternative activities in the context where opioid use had occurred can constrain opioid use and helps to maintain recovery. However, "frustration stress" that occurs when contingencies on these alternative activities unexpectedly change (e.g., job loss or divorce) is thought to threaten recovery by prompting a return to drug use. Yet it remains unclear whether frustration stress can result in a return to drug use, and if so, whether it returns to prior levels or to even greater levels. We examine the impact of unsignaled extinction of alternative reinforcement on opioid use. Rats were trained to respond for an etonitazene solution (5μg/ml, p.o.), then for food in alternating daily sessions. Subsequently, food and etonitazene were made concurrently available. Under concurrent availability conditions, rats were exposed to 1, 2, or 4 sessions of unsignaled food extinction, and effects on responding for etonitazene and food measured. When etonitazene was the only reinforcer available, rats earned 58.3±20.3μg/kg/session (mean±S.E.M.). When food was available in alternating sessions, etonitazene earned was unchanged (65.3±19.2μg/kg/session). Concurrent food availability decreased etonitazene earned (13.5±4.5μg/kg/session). Unsignaled food extinction returned etonitazene earnedto levels similar to (60.5±18.4μg/kg/session), but not greater than, those observed previously when etonitazene alone was available. Unsignaled extinction of alternative behavior controlling opioid use can result in increased opioid use, but this use does not rise beyond previous levels observed when opioid use is unconstrained by alternative reinforced behavior. Copyright © 2017 Elsevier B.V. All rights reserved.

  1. The simple beauty of the unexpected a natural philosopher's quest for trout and the meaning of everything

    CERN Document Server

    Gleiser, Marcelo

    2016-01-01

    Marcelo Gleiser has had a passion for science and fishing since he was a boy growing up on the beaches of Rio de Janeiro. Now a world-famous theoretical physicist with hundreds of scientific articles and several books of popular science to his credit, he felt it was time to connect with nature in less theoretical ways. After seeing a fly-fishing class on the Dartmouth College green, he decided to learn to fly-fish, a hobby, he says, that teaches humility. In The Simple Beauty of the Unexpected, Gleiser travels the world to scientific conferences, fishing wherever he goes. At each stop, he ponders how in the myriad ways physics informs the act of fishing; how, in its turn, fishing serves as a lens into nature s inner workings; and how science engages with questions of meaning and spirituality, inspiring a sense of mystery and awe of the not yet known. Personal and engaging, The Simple Beauty of the Unexpected is a scientist s tribute to nature, an affirmation of humanity s deep connection with and debt to Eart...

  2. High-Level Synthesis: Productivity, Performance, and Software Constraints

    Directory of Open Access Journals (Sweden)

    Yun Liang

    2012-01-01

    Full Text Available FPGAs are an attractive platform for applications with high computation demand and low energy consumption requirements. However, design effort for FPGA implementations remains high—often an order of magnitude larger than design effort using high-level languages. Instead of this time-consuming process, high-level synthesis (HLS tools generate hardware implementations from algorithm descriptions in languages such as C/C++ and SystemC. Such tools reduce design effort: high-level descriptions are more compact and less error prone. HLS tools promise hardware development abstracted from software designer knowledge of the implementation platform. In this paper, we present an unbiased study of the performance, usability and productivity of HLS using AutoPilot (a state-of-the-art HLS tool. In particular, we first evaluate AutoPilot using the popular embedded benchmark kernels. Then, to evaluate the suitability of HLS on real-world applications, we perform a case study of stereo matching, an active area of computer vision research that uses techniques also common for image denoising, image retrieval, feature matching, and face recognition. Based on our study, we provide insights on current limitations of mapping general-purpose software to hardware using HLS and some future directions for HLS tool development. We also offer several guidelines for hardware-friendly software design. For popular embedded benchmark kernels, the designs produced by HLS achieve 4X to 126X speedup over the software version. The stereo matching algorithms achieve between 3.5X and 67.9X speedup over software (but still less than manual RTL design with a fivefold reduction in design effort versus manual RTL design.

  3. A Stealth CME Bracketed between Slow and Fast Wind Producing Unexpected Geoeffectiveness

    Science.gov (United States)

    He, Wen; Liu, Ying D.; Hu, Huidong; Wang, Rui; Zhao, Xiaowei

    2018-06-01

    We investigate how a weak coronal mass ejection (CME) launched on 2016 October 8 without obvious signatures in the low corona produced a relatively intense geomagnetic storm. Remote sensing observations from SDO, STEREO, and SOHO and in situ measurements from Wind are employed to track the CME from the Sun to the Earth. Using a graduated cylindrical shell model, we estimate the propagation direction and the morphology of the CME near the Sun. CME kinematics are determined from the wide-angle imaging observations of STEREO A and are used to predict the CME arrival time and speed at the Earth. We compare ENLIL MHD simulation results with in situ measurements to illustrate the background solar wind where the CME was propagating. We also apply a Grad–Shafranov technique to reconstruct the flux-rope structure from in situ measurements in order to understand the geoeffectiveness associated with the CME magnetic field structure. Key results are obtained concerning how a weak CME can generate a relatively intense geomagnetic storm: (1) there were coronal holes at low latitudes, which could produce high speed streams (HSSs) to interact with the CME in interplanetary space; (2) the CME was bracketed between a slow wind ahead and an HSS behind, which enhanced the southward magnetic field inside the CME and gave rise to the unexpected geomagnetic storm.

  4. Subseasonal to Seasonal Predictions of U.S. West Coast High Water Levels

    Science.gov (United States)

    Khouakhi, A.; Villarini, G.; Zhang, W.; Slater, L. J.

    2017-12-01

    Extreme sea levels pose a significant threat to coastal communities, ecosystems, and assets, as they are conducive to coastal flooding, coastal erosion and inland salt-water intrusion. As sea levels continue to rise, these sea level extremes - including occasional minor coastal flooding experienced during high tide (nuisance floods) - are of concern. Extreme sea levels are increasing at many locations around the globe and have been attributed largely to rising mean sea levels associated with intra-seasonal to interannual climate processes such as the El Niño-Southern Oscillation (ENSO). Here, intra-seasonal to seasonal probabilistic forecasts of high water levels are computed at the Toke Point tide gage station on the US west coast. We first identify the main climate drivers that are responsible for high water levels and examine their predictability using General Circulation Models (GCMs) from the North American Multi-Model Ensemble (NMME). These drivers are then used to develop a probabilistic framework for the seasonal forecasting of high water levels. We focus on the climate controls on the frequency of high water levels using the number of exceedances above the 99.5th percentile and above the nuisance flood level established by the National Weather Service. Our findings indicate good forecast skill at the shortest lead time, with the skill that decreases as we increase the lead time. In general, these models aptly capture the year-to-year variability in the observational records.

  5. Leaching behavior of simulated high-level waste glass

    International Nuclear Information System (INIS)

    Kamizono, Hiroshi

    1987-03-01

    The author's work in the study on the leaching behavior of simulated high-level waste (HLW) glass were summarized. The subjects described are (1) leach rates at high temperatures, (2) effects of cracks on leach rates, (3) effects of flow rate on leach rates, and (4) an in-situ burial test in natural groundwater. In the following section, the leach rates obtained by various experiments were summarized and discussed. (author)

  6. Trunk Stability, Trunk Strength and Sport Performance Level in Judo.

    Directory of Open Access Journals (Sweden)

    David Barbado

    Full Text Available Although trunk muscle function has been suggested to be a determinant of judo performance, its contribution to high-level performance in this sport has been poorly studied. Therefore, several tests were used to assess the differences in trunk muscle function between 11 international and 14 national level judo practitioners (judokas. Trunk strength and endurance were assessed using isokinetic tests and core stability was assessed using two protocols: 1 sudden loading, to assess trunk responses to unexpected external perturbations; 2 stable and unstable sitting, to assess the participants' ability to control trunk balance. No differences between groups were found for trunk flexor isokinetic strength, trunk responses against lateral and posterior loading and trunk control while sitting. However, international level judokas showed significantly higher trunk extensor isokinetic strength (p <0.05 and lower trunk angular displacement after anterior trunk loading (p <0.05 than national level judokas. Few and low (r < 0.512 significant correlations were found between strength, endurance and stability parameters, which suggests that trunk strength and endurance are not limiting factors for trunk stability in competitive judokas. These results support the importance of trunk extensor strength and trunk stability against forward perturbations in elite judo performance.

  7. Artificial Heads for High-Level Impulse Sound Measurement

    National Research Council Canada - National Science Library

    Buck, K

    1999-01-01

    If the Insertion Loss (IL) of hearing protectors has to be determined with very high impulse or continuous noise levels, the acoustic insulation of the Artificial Test Fixture has to exceed at least the Insertion Loss (IL...

  8. Unexpected large room-temperature ferromagnetism in porous Cu{sub 2}O thin films

    Energy Technology Data Exchange (ETDEWEB)

    Hou, Xue [College of Physics Science & Information Engineering, Hebei Normal University, Shijiazhuang 050024 (China); Key Laboratory of Advanced Films of Hebei Province, Shijiazhuang 050024 (China); Sun, Huiyuan, E-mail: huiyuansun@126.com [College of Physics Science & Information Engineering, Hebei Normal University, Shijiazhuang 050024 (China); Key Laboratory of Advanced Films of Hebei Province, Shijiazhuang 050024 (China); Liu, Lihu; Jia, Xiaoxuan; Liu, Huiyuan [College of Physics Science & Information Engineering, Hebei Normal University, Shijiazhuang 050024 (China); Key Laboratory of Advanced Films of Hebei Province, Shijiazhuang 050024 (China)

    2015-05-15

    Porous Cu{sub 2}O films have been fabricated on porous anodic alumina substrates using DC-reactive magnetron sputtering with pure Cu targets, and unexpectedly large room temperature ferromagnetism has been observed in the films. The maximum saturation magnetic moment along the out-of-plane direction was as high as 94 emu/cm{sup 3}. Photoluminescence spectra show that the ferromagnetism originates with oxygen vacancies. The ferromagnetism could be adjusted by changing the concentration of oxygen vacancies through annealing in an oxygen atmosphere. These observations suggest that the origin of the ferromagnetism is due to coupling between oxygen vacancies with local magnetic moments in the porous Cu{sub 2}O films, which can occur either directly through exchange interactions between oxygen vacancies, or through the mediation of conduction electrons. Such a ferromagnet without the presence of any ferromagnetic dopant may find applications in spintronic devices. - Highlights: • Porous Cu{sub 2}O films were deposited on porous anodic alumina (PAA) substrates. • Significant room-temperature ferromagnetism has been observed in porous Cu{sub 2}O films. • Ferromagnetism of Cu{sub 2}O films exhibited different magnetic signals with the field. • The saturation magnetization is 94 emu/cm{sup 3} with an out-of-plane.

  9. Technologies for recovery of transuranics and immobilization of non-high-level wastes

    International Nuclear Information System (INIS)

    Richardson, G.L.

    1976-06-01

    This paper supplements the preceding Symposium paper on ''Treatment Technologies for Non-High-Level Wastes (U.S.A.)'' by C. R. Cooley and D. E. Clark (HEDL-SA-851), and covers the additional treatment technologies in use and under development for recovering transuranics and immobilizing non-high-level wastes for transportation and storage. Methods used for nondestructive assay (NDA) of TRU elements in non-high-level wastes are also discussed briefly

  10. Development of C-lignin with G/S-lignin and lipids in orchid seed coats – an unexpected diversity exposed by ATR-FT-IR spectroscopy

    DEFF Research Database (Denmark)

    Barsberg, Søren Talbro; Lee, Y.-I.; Rasmussen, Hanne Nina

    2018-01-01

    Cite this article: Barsberg ST, Lee Y-I, Rasmussen HN. Development of C-lignin with G/S-lignin and lipids in orchid seed coats – an unexpected diversity exposed by ATR-FT-IR spectroscopy. Seed Science Research https:// doi.org/10.1017/S0960258517000344......Cite this article: Barsberg ST, Lee Y-I, Rasmussen HN. Development of C-lignin with G/S-lignin and lipids in orchid seed coats – an unexpected diversity exposed by ATR-FT-IR spectroscopy. Seed Science Research https:// doi.org/10.1017/S0960258517000344...

  11. Inefficient postural responses to unexpected slips during walking in older adults.

    Science.gov (United States)

    Tang, P F; Woollacott, M H

    1998-11-01

    Slips account for a high percentage of falls and subsequent injuries in community-dwelling older adults but not in young adults. This phenomenon suggests that although active and healthy older adults preserve a mobility level comparable to that of young adults, these older adults may have difficulty generating efficient reactive postural responses when they slip. This study tested the hypothesis that active and healthy older adults use a less effective reactive balance strategy than young adults when experiencing an unexpected forward slip occurring at heel strike during walking. This less effective balance strategy would be manifested by slower and smaller postural responses, altered temporal and spatial organization of the postural responses, and greater upper trunk instability after the slip. Thirty-three young adults (age range=19-34 yrs, mean=25+/-4 yrs) and 32 community-dwelling older adults (age range=70-87 yrs, mean=74+/-14 yrs) participated. Subjects walked across a movable forceplate which simulated a forward slip at heel strike. Surface electromyography was recorded from bilateral leg, thigh, hip, and trunk muscles. Kinematic data were collected from the right (perturbed) side of the body. Although the predominant postural muscles and the activation sequence of these muscles were similar between the two age groups, the postural responses of older adults were of longer onset latencies, smaller magnitudes, and longer burst durations compared to young adults. Older adults also showed a longer coactivation duration for the ankle, knee, and trunk agonist/antagonist pairs on the perturbed side and for the knee agonist/antagonist pair on the nonperturbed side. Behaviorally, older adults became less stable after the slips. This was manifested by a higher incidence of being tripped (21 trials in older vs 5 trials in young adults) and a greater trunk hyperextension with respect to young adults. Large arm elevation was frequently used by older adults to assist in

  12. Remediation and production of low-sludge high-level waste glasses

    International Nuclear Information System (INIS)

    Ramsey, W.G.; Brown, K.G.; Beam, D.C.

    1994-01-01

    High-level radioactive sludge will constitute 24-28 oxide weight percent of the high-level waste glass produced at the Savannah River Site. A recent melter campaign using non-radioactive, simulated feed was performed with a sludge content considerably lower than 24 percent. The resulting glass was processed and shown to have acceptable durability. However, the durability was lower than predicted by the durability algorithm. Additional melter runs were performed to demonstrate that low sludge feed could be remediated by simply adding sludge oxides. The Product Composition Control System, a computer code developed to predict the proper feed composition for production of high-level waste glass, was utilized to determine the necessary chemical additions. The methodology used to calculate the needed feed additives, the effects of sludge oxides on glass production, and the resulting glass durability are discussed

  13. Sudden Unexpected Death in Epilepsy: A Retrospective Autopsy Study of 112 Epileptic Patients.

    Science.gov (United States)

    Esen Melez, İpek; Arslan, Murat Nihat; Melez, Deniz Oğuzhan; Şanli, Ahmet Necati; Koç, Sermet

    2017-09-01

    Sudden unexpected deaths comprise the most important and worthy investigation case profiles in both neurology and forensic medicine. Epilepsy, which is one of the neuropathological causes of sudden unexpected deaths, is an important disorder having mysterious aspects. The aim of this study is to make common the points of view between neurology and forensic medicine experts and to discuss the features of the findings together with the related clinical hypotheses, leading to the differential diagnosis of sudden unexpected death in epilepsy (SUDEP) by presenting autopsy findings and available medical data of patients who had a prior diagnosis of epilepsy. In Istanbul, the cases of 20334 autopsied patients who were referred to The Ministry of Justice Council of Forensic Medicine between 2007 and 2011 were identified from the complete forensic autopsy data of the city and were retrospectively reviewed. Patients who had a prior diagnosis of epilepsy were included. Both descriptive and inferential statistical analyses were performed through the parameters of demographical data, physical properties, incident features, macroscopic-microscopic autopsy findings, and cause of death initially for all cases and then separately for SUDEP cases. Among the 20334 patients, 112 were determined to have a prior diagnosis of epilepsy. A possible macroscopic and/or microscopic epileptic focus was present in 23 (20.5%) of these 112 cases. The cause of death was determined to be SUDEP in 40 (35.7%) cases, while it could not be determined in 28 (25%) cases. Among patients whose death cause was considered as SUDEP, the male-to-female ratio was 1.1:1, while the mean age was 31.5±13.9 years in males and 29.6±12.9 years in females. The presence of hypertrophy and myocardial scar tissue findings in the microscopic examination were significantly more frequent among patients determined to have died from cardiovascular diseases compared to patients in the SUDEP group (p=0.001 for each finding

  14. The ARES High-level Intermediate Representation

    Energy Technology Data Exchange (ETDEWEB)

    Moss, Nicholas David [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-03-03

    The LLVM intermediate representation (IR) lacks semantic constructs for depicting common high-performance operations such as parallel and concurrent execution, communication and synchronization. Currently, representing such semantics in LLVM requires either extending the intermediate form (a signi cant undertaking) or the use of ad hoc indirect means such as encoding them as intrinsics and/or the use of metadata constructs. In this paper we discuss a work in progress to explore the design and implementation of a new compilation stage and associated high-level intermediate form that is placed between the abstract syntax tree and when it is lowered to LLVM's IR. This highlevel representation is a superset of LLVM IR and supports the direct representation of these common parallel computing constructs along with the infrastructure for supporting analysis and transformation passes on this representation.

  15. Language and music: differential hemispheric dominance in detecting unexpected errors in the lyrics and melody of memorized songs.

    Science.gov (United States)

    Yasui, Takuya; Kaga, Kimitaka; Sakai, Kuniyoshi L

    2009-02-01

    Using magnetoencephalography (MEG), we report here the hemispheric dominance of the auditory cortex that is selectively modulated by unexpected errors in the lyrics and melody of songs (lyrics and melody deviants), thereby elucidating under which conditions the lateralization of auditory processing changes. In experiment 1 using familiar songs, we found that the dipole strength of responses to the lyrics deviants was left-dominant at 140 ms (M140), whereas that of responses to the melody deviants was right-dominant at 130 ms (M130). In experiment 2 using familiar songs with a constant syllable or pitch, the dipole strength of frequency mismatch negativity elicited by oddballs was left-dominant. There were significant main effects of experiment (1 and 2) for the peak latencies and for the coordinates of the dipoles, indicating that the M140 and M130 were not the frequency mismatch negativity. In experiment 3 using newly memorized songs, the right-dominant M130 was observed only when the presented note was unexpected one, independent of perceiving unnatural pitch transitions (i.e., perceptual saliency) and of selective attention to the melody of songs. The consistent right-dominance of the M130 between experiments 1 and 3 suggests that the M130 in experiment 1 is due to unexpected notes deviating from well-memorized songs. On the other hand, the left-dominant M140 was elicited by lyrics deviants, suggesting the influence of top-down linguistic information and the memory of the familiar songs. We thus conclude that the left- lateralized M140 and right-lateralized M130 reflect the expectation based on top-down information of language and music, respectively.

  16. CAMAC and high-level-languages

    International Nuclear Information System (INIS)

    Degenhardt, K.H.

    1976-05-01

    A proposal for easy programming of CAMAC systems with high-level-languages (FORTRAN, RTL/2, etc.) and interpreters (BASIC, MUMTI, etc.) using a few subroutines and a LAM driver is presented. The subroutines and the LAM driver are implemented for PDP11/RSX-11M and for the CAMAC controllers DEC CA11A (branch controller), BORER type 1533A (single crate controller) and DEC CA11F (single crate controller). Mixed parallel/serial CAMAC systems employing KINETIC SYSTEMS serial driver mod. 3992 and serial crate controllers mod. 3950 are implemented for all mentioned parallel controllers, too. DMA transfers from or to CAMAC modules using non-processor-request controllers (BORER type 1542, DEC CA11FN) are available. (orig.) [de

  17. Relationships between field performance tests in high-level soccer players

    DEFF Research Database (Denmark)

    Ingebrigtsen, Jørgen; Brochmann, Marit; Castagna, Carlo

    2014-01-01

    after two and four minutes of the Yo-Yo IR tests by testing 57 high-level soccer players. All players played regularly in one of the three highest levels of Norwegian soccer and were tested during three sessions on three consecutive days. Large correlations were observed between Yo-Yo IR1 and IR2 test...... using only one of the Yo-Yo tests and a RSA test, in a general soccer-specific field test protocol. The sub-maximal heart rate measures during Yo-Yo tests are reproducible and may be utilized for frequent, time-efficient and non-exhaustive testing of intermittent exercise capacity of high-level soccer...

  18. High-level waste-form-product performance evaluation

    International Nuclear Information System (INIS)

    Bernadzikowski, T.A.; Allender, J.S.; Stone, J.A.; Gordon, D.E.; Gould, T.H. Jr.; Westberry, C.F. III.

    1982-01-01

    Seven candidate waste forms were evaluated for immobilization and geologic disposal of high-level radioactive wastes. The waste forms were compared on the basis of leach resistance, mechanical stability, and waste loading. All forms performed well at leaching temperatures of 40, 90, and 150 0 C. Ceramic forms ranked highest, followed by glasses, a metal matrix form, and concrete. 11 tables

  19. High-level neutron coincidence counter (HLNCC): users' manual

    International Nuclear Information System (INIS)

    Krick, M.S.; Menlove, H.O.

    1979-06-01

    This manual describes the portable High-Level Neutron Coincidence Counter (HLNCC) developed at the Los Alamos Scientific Laboratory (LASL) for the assay of plutonium, particularly by inspectors of the International Atomic Energy Agency (IAEA). The counter is designed for the measurement of the effective 240 Pu mass in plutonium samples which may have a high plutonium content. The following topics are discussed: principle of operation, description of the system, operating procedures, and applications

  20. High level waste canister emplacement and retrieval concepts study

    International Nuclear Information System (INIS)

    1975-09-01

    Several concepts are described for the interim (20 to 30 years) storage of canisters containing high level waste, cladding waste, and intermediate level-TRU wastes. It includes requirements, ground rules and assumptions for the entire storage pilot plant. Concepts are generally evaluated and the most promising are selected for additional work. Follow-on recommendations are made

  1. High-level, but not low-level, motion perception is impaired in patients with schizophrenia.

    Science.gov (United States)

    Kandil, Farid I; Pedersen, Anya; Wehnes, Jana; Ohrmann, Patricia

    2013-01-01

    Smooth pursuit eye movements are compromised in patients with schizophrenia and their first-degree relatives. Although research has demonstrated that the motor components of smooth pursuit eye movements are intact, motion perception has been shown to be impaired. In particular, studies have consistently revealed deficits in performance on tasks specific to the high-order motion area V5 (middle temporal area, MT) in patients with schizophrenia. In contrast, data from low-level motion detectors in the primary visual cortex (V1) have been inconsistent. To differentiate between low-level and high-level visual motion processing, we applied a temporal-order judgment task for motion events and a motion-defined figure-ground segregation task using patients with schizophrenia and healthy controls. Successful judgments in both tasks rely on the same low-level motion detectors in the V1; however, the first task is further processed in the higher-order motion area MT in the magnocellular (dorsal) pathway, whereas the second task requires subsequent computations in the parvocellular (ventral) pathway in visual area V4 and the inferotemporal cortex (IT). These latter structures are supposed to be intact in schizophrenia. Patients with schizophrenia revealed a significantly impaired temporal resolution on the motion-based temporal-order judgment task but only mild impairment in the motion-based segregation task. These results imply that low-level motion detection in V1 is not, or is only slightly, compromised; furthermore, our data restrain the locus of the well-known deficit in motion detection to areas beyond the primary visual cortex.

  2. Benefits and unexpected artifacts of biplanar digital slot-scanning imaging in children

    Energy Technology Data Exchange (ETDEWEB)

    Blumer, Steven L. [Nemours/A.I duPont Hospital for Children, Department of Medical Imaging, Wilmington, DE (United States); Dinan, David [Nemours Children' s Hospital, Orlando, FL (United States); Grissom, Leslie E. [Nemours/Alfred I. duPont Hospital for Children, Department of Radiology, Wilmington, DE (United States)

    2014-07-15

    Biplanar digital slot-scanning allows for relatively low-dose orthopedic imaging, an advantage in imaging children given the growing concerns regarding radiosensitivity. We have used this system for approximately 1 year for orthopedic imaging of the spine and lower extremities. We have noted advantages of using the digital slot-scanning system when compared with computed radiographic and standard digital radiographic imaging systems, but we also found unexpected but common imaging artifacts that are the direct result of the imaging method and that have not been reported. This pictorial essay serves to familiarize radiologists with the advantages of the digital slot-scanning system as well as imaging artifacts common with this new technology. (orig.)

  3. High-level waste melter alternatives assessment report

    Energy Technology Data Exchange (ETDEWEB)

    Calmus, R.B.

    1995-02-01

    This document describes the Tank Waste Remediation System (TWRS) High-Level Waste (HLW) Program`s (hereafter referred to as HLW Program) Melter Candidate Assessment Activity performed in fiscal year (FY) 1994. The mission of the TWRS Program is to store, treat, and immobilize highly radioactive Hanford Site waste (current and future tank waste and encapsulated strontium and cesium isotopic sources) in an environmentally sound, safe, and cost-effective manner. The goal of the HLW Program is to immobilize the HLW fraction of pretreated tank waste into a vitrified product suitable for interim onsite storage and eventual offsite disposal at a geologic repository. Preparation of the encapsulated strontium and cesium isotopic sources for final disposal is also included in the HLW Program. As a result of trade studies performed in 1992 and 1993, processes planned for pretreatment of tank wastes were modified substantially because of increasing estimates of the quantity of high-level and transuranic tank waste remaining after pretreatment. This resulted in substantial increases in needed vitrification plant capacity compared to the capacity of original Hanford Waste Vitrification Plant (HWVP). The required capacity has not been finalized, but is expected to be four to eight times that of the HWVP design. The increased capacity requirements for the HLW vitrification plant`s melter prompted the assessment of candidate high-capacity HLW melter technologies to determine the most viable candidates and the required development and testing (D and T) focus required to select the Hanford Site HLW vitrification plant melter system. An assessment process was developed in early 1994. This document describes the assessment team, roles of team members, the phased assessment process and results, resulting recommendations, and the implementation strategy.

  4. High-level waste melter alternatives assessment report

    International Nuclear Information System (INIS)

    Calmus, R.B.

    1995-02-01

    This document describes the Tank Waste Remediation System (TWRS) High-Level Waste (HLW) Program's (hereafter referred to as HLW Program) Melter Candidate Assessment Activity performed in fiscal year (FY) 1994. The mission of the TWRS Program is to store, treat, and immobilize highly radioactive Hanford Site waste (current and future tank waste and encapsulated strontium and cesium isotopic sources) in an environmentally sound, safe, and cost-effective manner. The goal of the HLW Program is to immobilize the HLW fraction of pretreated tank waste into a vitrified product suitable for interim onsite storage and eventual offsite disposal at a geologic repository. Preparation of the encapsulated strontium and cesium isotopic sources for final disposal is also included in the HLW Program. As a result of trade studies performed in 1992 and 1993, processes planned for pretreatment of tank wastes were modified substantially because of increasing estimates of the quantity of high-level and transuranic tank waste remaining after pretreatment. This resulted in substantial increases in needed vitrification plant capacity compared to the capacity of original Hanford Waste Vitrification Plant (HWVP). The required capacity has not been finalized, but is expected to be four to eight times that of the HWVP design. The increased capacity requirements for the HLW vitrification plant's melter prompted the assessment of candidate high-capacity HLW melter technologies to determine the most viable candidates and the required development and testing (D and T) focus required to select the Hanford Site HLW vitrification plant melter system. An assessment process was developed in early 1994. This document describes the assessment team, roles of team members, the phased assessment process and results, resulting recommendations, and the implementation strategy

  5. An integrated framework for high level design of high performance signal processing circuits on FPGAs

    Science.gov (United States)

    Benkrid, K.; Belkacemi, S.; Sukhsawas, S.

    2005-06-01

    This paper proposes an integrated framework for the high level design of high performance signal processing algorithms' implementations on FPGAs. The framework emerged from a constant need to rapidly implement increasingly complicated algorithms on FPGAs while maintaining the high performance needed in many real time digital signal processing applications. This is particularly important for application developers who often rely on iterative and interactive development methodologies. The central idea behind the proposed framework is to dynamically integrate high performance structural hardware description languages with higher level hardware languages in other to help satisfy the dual requirement of high level design and high performance implementation. The paper illustrates this by integrating two environments: Celoxica's Handel-C language, and HIDE, a structural hardware environment developed at the Queen's University of Belfast. On the one hand, Handel-C has been proven to be very useful in the rapid design and prototyping of FPGA circuits, especially control intensive ones. On the other hand, HIDE, has been used extensively, and successfully, in the generation of highly optimised parameterisable FPGA cores. In this paper, this is illustrated in the construction of a scalable and fully parameterisable core for image algebra's five core neighbourhood operations, where fully floorplanned efficient FPGA configurations, in the form of EDIF netlists, are generated automatically for instances of the core. In the proposed combined framework, highly optimised data paths are invoked dynamically from within Handel-C, and are synthesized using HIDE. Although the idea might seem simple prima facie, it could have serious implications on the design of future generations of hardware description languages.

  6. Embedded Prompting May Function as Embedded Punishment: Detection of Unexpected Behavioral Processes within a Typical Preschool Teaching Strategy

    Science.gov (United States)

    Heal, Nicole A.; Hanley, Gregory P.

    2011-01-01

    This study describes an unexpected behavioral process that influenced behavior during the teaching of concepts to a 4-year-old girl. The efficacy of and preference for three strategies that varied in teacher directedness were assessed in a multielement design and concurrent-chains arrangement, respectively. The strategy that involved the most…

  7. In-situ nitrite analysis in high level waste tanks

    International Nuclear Information System (INIS)

    O'Rourke, P.E.; Prather, W.S.; Livingston, R.R.

    1992-01-01

    The Savannah River Site produces special nuclear materials used in the defense of the United States. Most of the processes at SRS are primarily chemical separations and purifications. In-situ chemical analyses help improve the safety, efficiency and quality of these operations. One area where in situ fiberoptic spectroscopy can have a great impact is the management of high level radioactive waste. High level radioactive waste at SRS is stored in more than 50 large waste tanks. The waste exists as a slurry of nitrate salts and metal hydroxides at pH's higher than 10. Sodium Nitrite is added to the tanks as a corrosion inhibitor. In-situ fiberoptic probes are being developed to measure the nitrate, nitrite and hydroxide concentrations in both liquid and solid fractions. Nitrite levels can be measured between 0.01M and 1M in a 1mm pathlength optical cell

  8. Cermet high level waste forms: a pregress report

    International Nuclear Information System (INIS)

    Aaron, W.S.; Quinby, T.C.; Kobisk, E.H.

    1978-06-01

    The fixation of high level radioactive waste from both commercial and DOE defense sources as cermets is currently under study. This waste form consists of a continuous iron-nickel base metal matrix containing small particles of fission product oxides. Preliminary evaluations of cermets fabricated from a variety of simulated wastes indicate they possess properties providing advantages over other waste forms presently being considered, namely thermal conductivity, waste loading levels, and leach resistance. This report describes the progress of this effort, to date, since its initiation in 1977

  9. Proposed classification scheme for high-level and other radioactive wastes

    International Nuclear Information System (INIS)

    Kocher, D.C.; Croff, A.G.

    1986-01-01

    The Nuclear Waste Policy Act (NWPA) of 1982 defines high-level (radioactive) waste (HLW) as (A) the highly radioactive material resulting from the reprocessing of spent nuclear fuel...that contains fission products in sufficient concentrations; and (B) other highly radioactive material that the Commission...determines...requires permanent isolation. This paper presents a generally applicable quantitative definition of HLW that addresses the description in paragraph B. The approach also results in definitions of other wastes classes, i.e., transuranic (TRU) and low-level waste (LLW). The basic waste classification scheme that results from the quantitative definitions of highly radioactive and requires permanent isolation is depicted. The concentrations of radionuclides that correspond to these two boundaries, and that may be used to classify radioactive wastes, are given

  10. Acoustic properties of perforates under high level multi-tone excitation

    OpenAIRE

    Bodén, Hans

    2013-01-01

    This paper discusses the effect of high level multi-tone acoustic excitation on the acoustic properties of perforates. It is based on a large experimental study of the nonlinear properties of these types of samples without mean grazing or bias flow. Compared to previously published results the present investigation concentrates on the effect of multiple harmonics. It is known from previous studies that high level acoustic excitation at one frequency will change the acoustic impedance of perfo...

  11. ATW system impact on high-level waste

    International Nuclear Information System (INIS)

    Arthur, E.D.

    1992-01-01

    This report discusses the Accelerator Transmutation of Waste (ATW) concept which aims at destruction of key long-lived radionuclides in high-level nuclear waste (HLW), both fission products and actinides. This focus makes it different from most other transmutation concepts which concentrate primarily on actinide burning. The ATW system uses an accelerator-driven, sub-critical assembly to create an intense thermal neutron environment for radionuclide transmutation. This feature allows rapid transmutation under low-inventory system conditions, which in turn, has a direct impact on the size of chemical separations and materials handling components of the system. Inventories in ATW are factors of eight to thirty times smaller than reactor systems of equivalent thermal power. Chemical separations systems are relatively small in scale and can be optimized to achieve high decontamination factors and minimized waste streams. The low-inventory feature also directly impacts material amounts remaining in the system at its end of life. In addition to its low-inventory operation, the accelerator-driven neutron source features of ATW are key to providing a sufficient level of neutrons to allow transmutation of long-lived fission products

  12. Teaching a High-Level Contextualized Mathematics Curriculum to Adult Basic Learners

    Science.gov (United States)

    Showalter, Daniel A.; Wollett, Chelsie; Reynolds, Sharon

    2014-01-01

    This paper reports on the implementation of a high level contextualized mathematics curriculum by 12 adult basic instructors in a midwestern state. The 10-week pilot curriculum embedded high level mathematics in contexts that were familiar to adult learners. Instructors' weekly online posts were coded, and the following themes emerged: (a)…

  13. Unexpected Far-Ultraviolet Photometric Characteristics On Mimas

    Science.gov (United States)

    Royer, E. M.; Hendrix, A. R.

    2013-12-01

    While infrared and visible are the most common wavelength domains used to investigate planetary surfaces, ultraviolet (UV) data are significant and useful. Here, we present the first far-UV phase curves of Mimas, thus displaying another piece of the Saturnian System puzzle. Our preliminary results shows that, one more time, Mimas surface properties are far from what we was expected. Namely, we observe a leading hemisphere brighter than the trailing hemisphere at some far-UV wavelengths. We used the far-UV channel of the Cassini/UVIS instrument, ranging from 118 to 190 nm. Disk-integrated phase curves for the leading hemisphere and the trailing hemisphere, at 180nm, have been produced. Data points span from 0.5 to 163.5 degrees in phase angle. Mimas displays a leading hemisphere brighter than its trailing hemisphere, when theory and previous Voyager observations at longer wavelengths attest of a brighter trailing hemisphere due to the impact of the E-ring grains on this face of the satellite. Surprisingly, UVIS data show a very bright opposition effect on Mimas leading hemisphere, greater than what is observed on Tethys or Dione leading hemisphere at the same wavelength of 180 nm. Preliminary results of photometric properties modeling seem to indicate an important contribution of the coherent-backscattering process in the opposition surge. Exogenic processes such as bombardment by energetic electrons and/or E-ring grains are discussed to explain this unexpected surface property of Mimas.

  14. Unexpected heterogeneity derived from Cas9 ribonucleoprotein-introduced clonal cells at the HPRT1 locus.

    Science.gov (United States)

    Sakuma, Tetsushi; Mochida, Keiji; Nakade, Shota; Ezure, Toru; Minagawa, Sachi; Yamamoto, Takashi

    2018-04-01

    Single-cell cloning is an essential technique for establishing genome-edited cell clones mediated by programmable nucleases such as CRISPR-Cas9. However, residual genome-editing activity after single-cell cloning may cause heterogeneity in the clonal cells. Previous studies showed efficient mutagenesis and rapid degradation of CRISPR-Cas9 components in cultured cells by introducing Cas9 ribonucleoproteins (RNPs). In this study, we investigated how the timing for single-cell cloning of Cas9 RNP-transfected cells affected the heterogeneity of the resultant clones. We carried out transfection of Cas9 RNPs targeting several loci in the HPRT1 gene in HCT116 cells, followed by single-cell cloning at 24, 48, 72 hr and 1 week post-transfection. After approximately 3 weeks of incubation, the clonal cells were collected and genotyped by high-resolution microchip electrophoresis and Sanger sequencing. Unexpectedly, long-term incubation before single-cell cloning resulted in highly heterogeneous clones. We used a lipofection method for transfection, and the media containing transfectable RNPs were not removed before single-cell cloning. Therefore, the active Cas9 RNPs were considered to be continuously incorporated into cells during the precloning incubation. Our findings provide a warning that lipofection of Cas9 RNPs may cause continuous introduction of gene mutations depending on the experimental procedures. © 2018 Molecular Biology Society of Japan and John Wiley & Sons Australia, Ltd.

  15. Adapting high-level language programs for parallel processing using data flow

    Science.gov (United States)

    Standley, Hilda M.

    1988-01-01

    EASY-FLOW, a very high-level data flow language, is introduced for the purpose of adapting programs written in a conventional high-level language to a parallel environment. The level of parallelism provided is of the large-grained variety in which parallel activities take place between subprograms or processes. A program written in EASY-FLOW is a set of subprogram calls as units, structured by iteration, branching, and distribution constructs. A data flow graph may be deduced from an EASY-FLOW program.

  16. Storage of High Level Nuclear Waste in Germany

    Directory of Open Access Journals (Sweden)

    Dietmar P. F. Möller

    2007-01-01

    Full Text Available Nuclear energy is very often used to generate electricity. But first the energy must be released from atoms what can be done in two ways: nuclear fusion and nuclear fission. Nuclear power plants use nuclear fission to produce electrical energy. The electrical energy generated in nuclear power plants does not produce polluting combustion gases but a renewable energy, an important fact that could play a key role helping to reduce global greenhouse gas emissions and tackling global warming especially as the electricity energy demand rises in the years ahead. This could be assumed as an ideal win-win situation, but the reverse site of the medal is that the production of high-level nuclear waste outweighs this advantage. Hence the paper attempt to highlight the possible state-of-art concepts for the safe and sustaining storage of high-level nuclear waste in Germany.

  17. Polytypism and unexpected strong interlayer coupling in two-dimensional layered ReS2

    Science.gov (United States)

    Qiao, Xiao-Fen; Wu, Jiang-Bin; Zhou, Linwei; Qiao, Jingsi; Shi, Wei; Chen, Tao; Zhang, Xin; Zhang, Jun; Ji, Wei; Tan, Ping-Heng

    2016-04-01

    Anisotropic two-dimensional (2D) van der Waals (vdW) layered materials, with both scientific interest and application potential, offer one more dimension than isotropic 2D materials to tune their physical properties. Various physical properties of 2D multi-layer materials are modulated by varying their stacking orders owing to significant interlayer vdW coupling. Multilayer rhenium disulfide (ReS2), a representative anisotropic 2D material, was expected to be randomly stacked and lack interlayer coupling. Here, we demonstrate two stable stacking orders, namely isotropic-like (IS) and anisotropic-like (AI) N layer (NL, N > 1) ReS2 are revealed by ultralow- and high-frequency Raman spectroscopy, photoluminescence and first-principles density functional theory calculation. Two interlayer shear modes are observed in AI-NL-ReS2 while only one shear mode appears in IS-NL-ReS2, suggesting anisotropic- and isotropic-like stacking orders in IS- and AI-NL-ReS2, respectively. This explicit difference in the observed frequencies identifies an unexpected strong interlayer coupling in IS- and AI-NL-ReS2. Quantitatively, the force constants of them are found to be around 55-90% of those of multilayer MoS2. The revealed strong interlayer coupling and polytypism in multi-layer ReS2 may stimulate future studies on engineering physical properties of other anisotropic 2D materials by stacking orders.Anisotropic two-dimensional (2D) van der Waals (vdW) layered materials, with both scientific interest and application potential, offer one more dimension than isotropic 2D materials to tune their physical properties. Various physical properties of 2D multi-layer materials are modulated by varying their stacking orders owing to significant interlayer vdW coupling. Multilayer rhenium disulfide (ReS2), a representative anisotropic 2D material, was expected to be randomly stacked and lack interlayer coupling. Here, we demonstrate two stable stacking orders, namely isotropic-like (IS) and

  18. Unexpected neuronal protection of SU5416 against 1-Methyl-4-phenylpyridinium ion-induced toxicity via inhibiting neuronal nitric oxide synthase.

    Directory of Open Access Journals (Sweden)

    Wei Cui

    Full Text Available SU5416 was originally designed as a potent and selective inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2 for cancer therapy. In this study, we have found for the first time that SU5416 unexpectedly prevented 1-methyl-4-phenylpyridinium ion (MPP(+-induced neuronal apoptosis in cerebellar granule neurons, and decreased 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP-induced loss of dopaminergic neurons and impairment of swimming behavior in zebrafish in a concentration-dependent manner. However, VEGFR-2 kinase inhibitor II, another specific VEGFR-2 inhibitor, failed to reverse neurotoxicity at the concentration exhibiting anti-angiogenic activity, strongly suggesting that the neuroprotective effect of SU5416 is independent from its anti-angiogenic action. SU5416 potently reversed MPP(+-increased intracellular nitric oxide level with an efficacy similar to 7-nitroindazole, a specific neuronal nitric oxide synthase (nNOS inhibitor. Western blotting analysis showed that SU5416 reduced the elevation of nNOS protein expression induced by MPP(+. Furthermore, SU5416 directly inhibited the enzyme activity of rat cerebellum nNOS with an IC(50 value of 22.7 µM. In addition, knock-down of nNOS expression using short hairpin RNA (shRNA abolished the neuroprotective effects of SU5416 against MPP(+-induced neuronal loss. Our results strongly demonstrate that SU5416 might exert its unexpected neuroprotective effects by concurrently reducing nNOS protein expression and directly inhibiting nNOS enzyme activity. In view of the capability of SU5416 to cross the blood-brain barrier and the safety for human use, our findings further indicate that SU5416 might be a novel drug candidate for neurodegenerative disorders, particularly those associated with NO-mediated neurotoxicity.

  19. 76 FR 35719 - Unexpected Urgent Refugee and Migration Needs Related to Libya and C[ocirc]te d'Ivoire

    Science.gov (United States)

    2011-06-20

    ... June 8, 2011 Unexpected Urgent Refugee and Migration Needs Related to Libya and C[ocirc]te d'Ivoire... laws of the United States, including section 2(c)(1) of the Migration and Refugee Assistance Act of... amount not to exceed $15 million from the United States Emergency Refugee and Migration Assistance Fund...

  20. Evidence against barium in the mushroom Trogia venenata as a cause of sudden unexpected deaths in Yunnan, China.

    Science.gov (United States)

    Zhang, Ying; Li, Yanchun; Wu, Gang; Feng, Bang; Yoell, Shanze; Yu, Zefen; Zhang, Keqin; Xu, Jianping

    2012-12-01

    This study examined barium concentrations in the mushroom Trogia venenata, the leading culprit for sudden unexpected deaths in Yunnan, southwest China. We found that barium concentrations in T. venenata from Yunnan were low and comparable to other foods, inconsistent with barium concentrations in this mushroom as a significant contributor to these deaths.

  1. High level secretion of cellobiohydrolases by Saccharomyces cerevisiae

    Directory of Open Access Journals (Sweden)

    Ahlgren Simon

    2011-09-01

    Full Text Available Abstract Background The main technological impediment to widespread utilization of lignocellulose for the production of fuels and chemicals is the lack of low-cost technologies to overcome its recalcitrance. Organisms that hydrolyze lignocellulose and produce a valuable product such as ethanol at a high rate and titer could significantly reduce the costs of biomass conversion technologies, and will allow separate conversion steps to be combined in a consolidated bioprocess (CBP. Development of Saccharomyces cerevisiae for CBP requires the high level secretion of cellulases, particularly cellobiohydrolases. Results We expressed various cellobiohydrolases to identify enzymes that were efficiently secreted by S. cerevisiae. For enhanced cellulose hydrolysis, we engineered bimodular derivatives of a well secreted enzyme that naturally lacks the carbohydrate-binding module, and constructed strains expressing combinations of cbh1 and cbh2 genes. Though there was significant variability in the enzyme levels produced, up to approximately 0.3 g/L CBH1 and approximately 1 g/L CBH2 could be produced in high cell density fermentations. Furthermore, we could show activation of the unfolded protein response as a result of cellobiohydrolase production. Finally, we report fermentation of microcrystalline cellulose (Avicel™ to ethanol by CBH-producing S. cerevisiae strains with the addition of beta-glucosidase. Conclusions Gene or protein specific features and compatibility with the host are important for efficient cellobiohydrolase secretion in yeast. The present work demonstrated that production of both CBH1 and CBH2 could be improved to levels where the barrier to CBH sufficiency in the hydrolysis of cellulose was overcome.

  2. A "present" for the future: the unexpected value of rediscovery.

    Science.gov (United States)

    Zhang, Ting; Kim, Tami; Brooks, Alison Wood; Gino, Francesca; Norton, Michael I

    2014-10-01

    Although documenting everyday activities may seem trivial, four studies reveal that creating records of the present generates unexpected benefits by allowing future rediscoveries. In Study 1, we used a time-capsule paradigm to show that individuals underestimate the extent to which rediscovering experiences from the past will be curiosity provoking and interesting in the future. In Studies 2 and 3, we found that people are particularly likely to underestimate the pleasure of rediscovering ordinary, mundane experiences, as opposed to extraordinary experiences. Finally, Study 4 demonstrates that underestimating the pleasure of rediscovery leads to time-inconsistent choices: Individuals forgo opportunities to document the present but then prefer rediscovering those moments in the future to engaging in an alternative fun activity. Underestimating the value of rediscovery is linked to people's erroneous faith in their memory of everyday events. By documenting the present, people provide themselves with the opportunity to rediscover mundane moments that may otherwise have been forgotten. © The Author(s) 2014.

  3. Wikiwijs: An unexpected journey and the lessons learned towards OER

    Directory of Open Access Journals (Sweden)

    Robert Schuwer

    2014-04-01

    Full Text Available The Dutch Ministry of Education, Culture and Science has funded a five years program to encourage the use, creation and sharing of Open Educational Resources (OER by teachers from various types of education. This program is known as Wikiwijs. Ultimo 2013, the program has come to an end. As some of the assumptions at the start of Wikiwijs proved to work out in unexpected ways the lessons learned could fuel the next steps in developing Wikiwijs. Besides, other national initiatives on opening up education may also benefit from the lessons learned reported here. The main conclusion from five years Wikiwijs was that to accomplish mainstreaming OER, the Wikiwijs program should go along with other interventions that are more oriented toward prescriptive policies and regulations. In particular: the Dutch government should be more directive in persuading executive boards and teachers on schools to adopt OER as an important part of educational reform and the acquisition of 21st century skills.

  4. High-Level Heteroatom Doped Two-Dimensional Carbon Architectures for Highly Efficient Lithium-Ion Storage

    Directory of Open Access Journals (Sweden)

    Zhijie Wang

    2018-04-01

    Full Text Available In this work, high-level heteroatom doped two-dimensional hierarchical carbon architectures (H-2D-HCA are developed for highly efficient Li-ion storage applications. The achieved H-2D-HCA possesses a hierarchical 2D morphology consisting of tiny carbon nanosheets vertically grown on carbon nanoplates and containing a hierarchical porosity with multiscale pore size. More importantly, the H-2D-HCA shows abundant heteroatom functionality, with sulfur (S doping of 0.9% and nitrogen (N doping of as high as 15.5%, in which the electrochemically active N accounts for 84% of total N heteroatoms. In addition, the H-2D-HCA also has an expanded interlayer distance of 0.368 nm. When used as lithium-ion battery anodes, it shows excellent Li-ion storage performance. Even at a high current density of 5 A g−1, it still delivers a high discharge capacity of 329 mA h g−1 after 1,000 cycles. First principle calculations verifies that such unique microstructure characteristics and high-level heteroatom doping nature can enhance Li adsorption stability, electronic conductivity and Li diffusion mobility of carbon nanomaterials. Therefore, the H-2D-HCA could be promising candidates for next-generation LIB anodes.

  5. Nonseizure SUDEP: Sudden unexpected death in epilepsy without preceding epileptic seizures.

    Science.gov (United States)

    Lhatoo, Samden D; Nei, Maromi; Raghavan, Manoj; Sperling, Michael; Zonjy, Bilal; Lacuey, Nuria; Devinsky, Orrin

    2016-07-01

    To describe the phenomenology of monitored sudden unexpected death in epilepsy (SUDEP) occurring in the interictal period where death occurs without a seizure preceding it. We report a case series of monitored definite and probable SUDEP where no electroclinical evidence of underlying seizures was found preceding death. Three patients (two definite and one probable) had SUDEP. They had a typical high SUDEP risk profile with longstanding intractable epilepsy and frequent generalized tonic-clonic seizures (GTCS). All patients had varying patterns of respiratory and bradyarrhythmic cardiac dysfunction with profound electroencephalography (EEG) suppression. In two patients, patterns of cardiorespiratory failure were similar to those seen in some patients in the Mortality in Epilepsy Monitoring Units Study (MORTEMUS). SUDEP almost always occur postictally, after GTCS and less commonly after a partial seizure. Monitored SUDEP or near-SUDEP cases without a seizure have not yet been reported in literature. When nonmonitored SUDEP occurs in an ambulatory setting without an overt seizure, the absence of EEG information prevents the exclusion of a subtle seizure. These cases confirm the existence of nonseizure SUDEP; such deaths may not be prevented by seizure detection-based devices. SUDEP risk in patients with epilepsy may constitute a spectrum of susceptibility wherein some are relatively immune, death occurs in others with frequent GTCS with one episode of seizure ultimately proving fatal, while in others still, death may occur even in the absence of a seizure. We emphasize the heterogeneity of SUDEP phenomena. Wiley Periodicals, Inc. © 2016 International League Against Epilepsy.

  6. Extending Java for High-Level Web Service Construction

    DEFF Research Database (Denmark)

    Christensen, Aske Simon; Møller, Anders; Schwartzbach, Michael Ignatieff

    2003-01-01

    We incorporate innovations from the project into the Java language to provide high-level features for Web service programming. The resulting language, JWIG, contains an advanced session model and a flexible mechanism for dynamic construction of XML documents, in particular XHTML. To support program...

  7. Design concepts of definitive disposal for high level radioactive wastes

    International Nuclear Information System (INIS)

    Badillo A, V.E.; Alonso V, G.

    2007-01-01

    It is excessively known the importance about finding a solution for the handling and disposition of radioactive waste of all level. However, the polemic is centered in the administration of high level radioactive waste and the worn out fuel, forgetting that the more important volumes of waste its are generated in the categories of low level wastes or of very low level. Depending on the waste that will be confined and of the costs, several technological modalities of definitive disposition exist, in function of the depth of the confinement. The concept of deep geologic storage, technological option proposed more than 40 years ago, it is a concept of isolation of waste of long half life placed in a deep underground installation dug in geologic formations that are characterized by their high stability and their low flow of underground water. In the last decades, they have registered countless progresses in technical and scientific aspects of the geologic storage, making it a reliable technical solution supported with many years of scientific work carried out by numerous institutions in the entire world. In this work the design concepts that apply some countries for the high level waste disposal that its liberate heat are revised and the different geologic formations that have been considered for the storage of this type of wastes. (Author)

  8. Safety analysis of the transportation of high-level radioactive waste

    International Nuclear Information System (INIS)

    Murphy, E.S.; Winegardner, W.K.

    1975-01-01

    An analysis of the risk from transportation of solidified high-level waste is being performed at Battelle-Northwest as part of a comprehensive study of the management of high-level waste. The risk analysis study makes use of fault trees to identify failure events and to specify combinations of events which could result in breach of containment and a release of radioactive material to the environment. Contributions to risk analysis methodology which have been made in connection with this study include procedures for identification of dominant failure sequences, methods for quantifying the effects of probabilistic failure events, and computer code development. Preliminary analysis based on evaluation of the rail transportation fault tree indicates that the dominant failure sequences for transportation of solidified high-level waste will be those related to railroad accidents. Detailed evaluation of rail accident failure sequences is proceeding and is making use of the limited frequency-severity data which is available in the literature. (U.S.)

  9. Unexpected Effects of a System-Distributed Mobile Application in Maternity Care: A Randomized Controlled Trial.

    Science.gov (United States)

    Ledford, Christy J W; Womack, Jasmyne J; Rider, Heather A; Seehusen, Angela B; Conner, Stephen J; Lauters, Rebecca A; Hodge, Joshua A

    2018-06-01

    As pregnant mothers increasingly engage in shared decision making regarding prenatal decisions, such as induction of labor, the patient's level of activation may influence pregnancy outcomes. One potential tool to increase patient activation in the clinical setting is mobile applications. However, research is limited in comparing mobile apps with other modalities of patient education and engagement tools. This study was designed to test the effectiveness of a mobile app as a replacement for a spiral notebook guide as a patient education and engagement tool in the prenatal clinical setting. This randomized controlled trial was conducted in the Women's Health Clinic and Family Health Clinic of three hospitals. Repeated-measures analysis of covariance was used to test intervention effects in the study sample of 205 patients. Mothers used a mobile app interface to more frequently record information about their pregnancy; however, across time, mothers using a mobile app reported a significant decrease in patient activation. The unexpected negative effects in the group of patients randomized to the mobile app prompt these authors to recommend that health systems pause before distributing their own version of mobile apps that may decrease patient activation. Mobile apps can be inherently empowering and engaging, but how a system encourages their use may ultimately determine their adoption and success.

  10. Interpersonal Movement Synchrony Responds to High- and Low-Level Conversational Constraints

    Directory of Open Access Journals (Sweden)

    Alexandra Paxton

    2017-07-01

    Full Text Available Much work on communication and joint action conceptualizes interaction as a dynamical system. Under this view, dynamic properties of interaction should be shaped by the context in which the interaction is taking place. Here we explore interpersonal movement coordination or synchrony—the degree to which individuals move in similar ways over time—as one such context-sensitive property. Studies of coordination have typically investigated how these dynamics are influenced by either high-level constraints (i.e., slow-changing factors or low-level constraints (i.e., fast-changing factors like movement. Focusing on nonverbal communication behaviors during naturalistic conversation, we analyzed how interacting participants' head movement dynamics were shaped simultaneously by high-level constraints (i.e., conversation type; friendly conversations vs. arguments and low-level constraints (i.e., perceptual stimuli; non-informative visual stimuli vs. informative visual stimuli. We found that high- and low-level constraints interacted non-additively to affect interpersonal movement dynamics, highlighting the context sensitivity of interaction and supporting the view of joint action as a complex adaptive system.

  11. High C-reactive protein levels are associated with depressive symptoms in schizophrenia.

    Science.gov (United States)

    Faugere, M; Micoulaud-Franchi, J-A; Faget-Agius, C; Lançon, C; Cermolacce, M; Richieri, R

    2018-01-01

    Depressive symptoms are frequently associated with schizophrenia symptoms. C - Reactive protein (CRP), a marker of chronic inflammation, had been found elevated in patients with schizophrenia and in patients with depressive symptoms. However, the association between CRP level and depressive symptoms has been poorly investigated in patients with schizophrenia. The only study conducted found an association between high CRP levels and antidepressant consumption, but not with depressive symptoms investigated with the Calgary Depression Rating Scale for Schizophrenia (CDSS). The aim of this study was to evaluate CRP levels and depressive symptoms in patients with schizophrenia, and to determine whether high CRP levels are associated with depressive symptoms and/or antidepressant consumption, independently of potential confounding factors, especially tobacco-smoking and metabolic syndrome. Three hundred and seven patients with schizophrenia were enrolled in this study (mean age = 35.74 years, 69.1% male gender). Depressive symptoms was investigated with the CDSS. Patients were classified in two groups: normal CRP level (≤ 3.0mg/L) and high CRP level (> 3.0mg/L). Current medication was recorded. 124 subjects (40.4%) were classified in the high CRP level group. After adjusting for confounding factors, these patients were found to have higher CDSS scores than those with normal CRP levels in multivariate analyses (p = 0.035, OR = 1.067, 95% CI = 1.004-1.132). No significant association between CRP levels and antidepressants consumption was found. The size sample is relatively small. The cut-off point for high cardiovascular risk was used to define the two groups. CRP was the sole marker of inflammation in this study and was collected at only one time point. The design of this study is cross-sectional and there are no conclusions about the directionality of the association between depression and inflammation in schizophrenia. This study found an association between high

  12. Homozygous and compound heterozygous mutations in the FBN1 gene: unexpected findings in molecular diagnosis of Marfan syndrome.

    Science.gov (United States)

    Arnaud, Pauline; Hanna, Nadine; Aubart, Mélodie; Leheup, Bruno; Dupuis-Girod, Sophie; Naudion, Sophie; Lacombe, Didier; Milleron, Olivier; Odent, Sylvie; Faivre, Laurence; Bal, Laurence; Edouard, Thomas; Collod-Beroud, Gwenaëlle; Langeois, Maud; Spentchian, Myrtille; Gouya, Laurent; Jondeau, Guillaume; Boileau, Catherine

    2017-02-01

    Marfan syndrome (MFS) is an autosomal-dominant connective tissue disorder usually associated with heterozygous mutations in the gene encoding fibrillin-1 (FBN1). Homozygous and compound heterozygous cases are rare events and have been associated with a clinical severe presentation. Report unexpected findings of homozygosity and compound heterozygosity in the course of molecular diagnosis of heterozygous MFS and compare the findings with published cases. In the context of molecular diagnosis of heterozygous MFS, systematic sequencing of the FBN1 gene was performed in 2500 probands referred nationwide. 1400 probands carried a heterozygous mutation in this gene. Unexpectedly, among them four homozygous cases (0.29%) and five compound heterozygous cases (0.36%) were identified (total: 0.64%). Interestingly, none of these cases carried two premature termination codon mutations in the FBN1 gene. Clinical features for these carriers and their families were gathered and compared. There was a large spectrum of severity of the disease in probands carrying two mutated FBN1 alleles, but none of them presented extremely severe manifestations of MFS in any system compared with carriers of only one mutated FBN1 allele. This observation is not in line with the severe clinical features reported in the literature for four homozygous and three compound heterozygous probands. Homozygotes and compound heterozygotes were unexpectedly identified in the course of molecular diagnosis of MFS. Contrary to previous reports, the presence of two mutated alleles was not associated with severe forms of MFS. Although homozygosity and compound heterozygosity are rarely found in molecular diagnosis, they should not be overlooked, especially among consanguineous families. However, no predictive evaluation of severity should be provided. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  13. High level waste fixation in cermet form

    International Nuclear Information System (INIS)

    Kobisk, E.H.; Aaron, W.S.; Quinby, T.C.; Ramey, D.W.

    1981-01-01

    Commercial and defense high level waste fixation in cermet form is being studied by personnel of the Isotopes Research Materials Laboratory, Solid State Division (ORNL). As a corollary to earlier research and development in forming high density ceramic and cermet rods, disks, and other shapes using separated isotopes, similar chemical and physical processing methods have been applied to synthetic and real waste fixation. Generally, experimental products resulting from this approach have shown physical and chemical characteristics which are deemed suitable for long-term storage, shipping, corrosive environments, high temperature environments, high waste loading, decay heat dissipation, and radiation damage. Although leach tests are not conclusive, what little comparative data are available show cermet to withstand hydrothermal conditions in water and brine solutions. The Soxhlet leach test, using radioactive cesium as a tracer, showed that leaching of cermet was about X100 less than that of 78 to 68 glass. Using essentially uncooled, untreated waste, cermet fixation was found to accommodate up to 75% waste loading and yet, because of its high thermal conductivity, a monolith of 0.6 m diameter and 3.3 m-length would have only a maximum centerline temperature of 29 K above the ambient value

  14. Unexpected Reading Dissociation in a Brazilian “nisei” with Crossed Aphasia

    Directory of Open Access Journals (Sweden)

    P. Caramelli

    1994-01-01

    Full Text Available There is an increased interest in reading impairments in the Japanese language, due to its particular writing system which includes two different scripts, Kanji (logograms and Kana (phonograms. Reading dissociations between Kanji and Kana have been described, showing that each system is processed differently by the cerebral hemispheres. We describe the case of a 68 year old Brazilian “nisei” (i.e. born from Japanese parents who had knowledge of both Japanese and Portuguese. He presented an ischemic stroke affecting the right hemisphere and subsequently developed a Broca's aphasia and an unexpected reading dissociation, with an impairment in Kana reading comprehension and a good performance in Kanji and in Portuguese. These findings suggest that the patient's right and left hemispheres have assumed opposite roles not only for oral but also for written language decodification.

  15. Multipurpose optimization models for high level waste vitrification

    International Nuclear Information System (INIS)

    Hoza, M.

    1994-08-01

    Optimal Waste Loading (OWL) models have been developed as multipurpose tools for high-level waste studies for the Tank Waste Remediation Program at Hanford. Using nonlinear programming techniques, these models maximize the waste loading of the vitrified waste and optimize the glass formers composition such that the glass produced has the appropriate properties within the melter, and the resultant vitrified waste form meets the requirements for disposal. The OWL model can be used for a single waste stream or for blended streams. The models can determine optimal continuous blends or optimal discrete blends of a number of different wastes. The OWL models have been used to identify the most restrictive constraints, to evaluate prospective waste pretreatment methods, to formulate and evaluate blending strategies, and to determine the impacts of variability in the wastes. The OWL models will be used to aid in the design of frits and the maximize the waste in the glass for High-Level Waste (HLW) vitrification

  16. Tracking at High Level Trigger in CMS

    CERN Document Server

    Tosi, Mia

    2016-01-01

    The trigger systems of the LHC detectors play a crucial role in determining the physics capabili- ties of the experiments. A reduction of several orders of magnitude of the event rate is needed to reach values compatible with detector readout, offline storage and analysis capability. The CMS experiment has been designed with a two-level trigger system: the Level-1 Trigger (L1T), implemented on custom-designed electronics, and the High Level Trigger (HLT), a stream- lined version of the CMS offline reconstruction software running on a computer farm. A software trigger system requires a trade-off between the complexity of the algorithms, the sustainable out- put rate, and the selection efficiency. With the computing power available during the 2012 data taking the maximum reconstruction time at HLT was about 200 ms per event, at the nominal L1T rate of 100 kHz. Track reconstruction algorithms are widely used in the HLT, for the reconstruction of the physics objects as well as in the identification of b-jets and ...

  17. High-level waste processing at the Savannah River Site: An update

    International Nuclear Information System (INIS)

    Marra, J.E.; Bennett, W.M.; Elder, H.H.; Lee, E.D.; Marra, S.L.; Rutland, P.L.

    1997-01-01

    The Defense Waste Processing Facility (DWPF) at the Savannah River Site (SRS) in Aiken, SC mg began immobilizing high-level radioactive waste in borosilicate glass in 1996. Currently, the radioactive glass is being produced as a ''sludge-only'' composition by combining washed high-level waste sludge with glass frit. The glass is poured in stainless steel canisters which will eventually be disposed of in a permanent, geological repository. To date, DWPF has produced about 100 canisters of vitrified waste. Future processing operations will, be based on a ''coupled'' feed of washed high-level waste sludge, precipitated cesium, and glass frit. This paper provides an update of the processing activities completed to date, operational/flowsheet problems encountered, and programs underway to increase production rates

  18. The Yo-Yo intermittent recovery test level 1 is reliable in young high-level soccer players

    Directory of Open Access Journals (Sweden)

    Dieter Deprez

    2014-11-01

    Full Text Available The aim of the study was to investigate test reliability of the Yo-Yo intermittent recovery test level 1 (YYIR1 in 36 high-level youth soccer players, aged between 13 and 18 years. Players were divided into three age groups (U15, U17 and U19 and completed three YYIR1 in three consecutive weeks. Pairwise comparisons were used to investigate test reliability (for distances and heart rate responses using technical error (TE, coefficient of variation (CV, intra-class correlation (ICC and limits of agreement (LOA with Bland-Altman plots. The mean YYIR1 distances for the U15, U17 and U19 groups were 2024 ± 470 m, 2404 ± 347 m and 2547 ± 337 m, respectively. The results revealed that the TEs varied between 74 and 172 m, CVs between 3.0 and 7.5%, and ICCs between 0.87 and 0.95 across all age groups for the YYIR1 distance. For heart rate responses, the TEs varied between 1 and 6 bpm, CVs between 0.7 and 4.8%, and ICCs between 0.73 and 0.97. The small ratio LOA revealed that any two YYIR1 performances in one week will not differ by more than 9 to 28% due to measurement error. In summary, the YYIR1 performance and the physiological responses have proven to be highly reliable in a sample of Belgian high-level youth soccer players, aged between 13 and 18 years. The demonstrated high level of intermittent endurance capacity in all age groups may be used for comparison of other prospective young soccer players.

  19. Screening of random peptide library of hemagglutinin from pandemic 2009 A(H1N1 influenza virus reveals unexpected antigenically important regions.

    Directory of Open Access Journals (Sweden)

    Wanghui Xu

    Full Text Available The antigenic structure of the membrane protein hemagglutinin (HA from the 2009 A(H1N1 influenza virus was dissected with a high-throughput screening method using complex antisera. The approach involves generating yeast cell libraries displaying a pool of random peptides of controllable lengths on the cell surface, followed by one round of fluorescence-activated cell sorting (FACS against antisera from mouse, goat and human, respectively. The amino acid residue frequency appearing in the antigenic peptides at both the primary sequence and structural level was determined and used to identify "hot spots" or antigenically important regions. Unexpectedly, different antigenic structures were seen for different antisera. Moreover, five antigenic regions were identified, of which all but one are located in the conserved HA stem region that is responsible for membrane fusion. Our findings are corroborated by several recent studies on cross-neutralizing H1 subtype antibodies that recognize the HA stem region. The antigenic peptides identified may provide clues for creating peptide vaccines with better accessibility to memory B cells and better induction of cross-neutralizing antibodies than the whole HA protein. The scheme used in this study enables a direct mapping of the antigenic regions of viral proteins recognized by antisera, and may be useful for dissecting the antigenic structures of other viral proteins.

  20. Maintenance of equilibrium point control during an unexpectedly loaded rapid limb movement.

    Science.gov (United States)

    Simmons, R W; Richardson, C

    1984-06-08

    Two experiments investigated whether the equilibrium point hypothesis or the mass-spring model of motor control subserves positioning accuracy during spring loaded, rapid, bi-articulated movement. For intact preparations, the equilibrium point hypothesis predicts response accuracy to be determined by a mixture of afferent and efferent information, whereas the mass-spring model predicts positioning to be under a direct control system. Subjects completed a series of load-resisted training trials to a spatial target. The magnitude of a sustained spring load was unexpectedly increased on selected trials. Results indicated positioning accuracy and applied force varied with increases in load, which suggests that the original efferent commands are modified by afferent information during the movement as predicted by the equilibrium point hypothesis.

  1. High-level radioactive waste repositories site selection plan

    International Nuclear Information System (INIS)

    Castanon, A.; Recreo, F.

    1985-01-01

    A general vision of the high level nuclear waste (HLNW) and/or nuclear spent fuel facilities site selection processes is given, according to the main international nuclear safety regulatory organisms quidelines and the experience from those countries which have reached a larger development of their national nuclear programs. (author)

  2. High Level Information Fusion (HLIF) with nested fusion loops

    Science.gov (United States)

    Woodley, Robert; Gosnell, Michael; Fischer, Amber

    2013-05-01

    Situation modeling and threat prediction require higher levels of data fusion in order to provide actionable information. Beyond the sensor data and sources the analyst has access to, the use of out-sourced and re-sourced data is becoming common. Through the years, some common frameworks have emerged for dealing with information fusion—perhaps the most ubiquitous being the JDL Data Fusion Group and their initial 4-level data fusion model. Since these initial developments, numerous models of information fusion have emerged, hoping to better capture the human-centric process of data analyses within a machine-centric framework. 21st Century Systems, Inc. has developed Fusion with Uncertainty Reasoning using Nested Assessment Characterizer Elements (FURNACE) to address challenges of high level information fusion and handle bias, ambiguity, and uncertainty (BAU) for Situation Modeling, Threat Modeling, and Threat Prediction. It combines JDL fusion levels with nested fusion loops and state-of-the-art data reasoning. Initial research has shown that FURNACE is able to reduce BAU and improve the fusion process by allowing high level information fusion (HLIF) to affect lower levels without the double counting of information or other biasing issues. The initial FURNACE project was focused on the underlying algorithms to produce a fusion system able to handle BAU and repurposed data in a cohesive manner. FURNACE supports analyst's efforts to develop situation models, threat models, and threat predictions to increase situational awareness of the battlespace. FURNACE will not only revolutionize the military intelligence realm, but also benefit the larger homeland defense, law enforcement, and business intelligence markets.

  3. Status of commercial nuclear high-level waste disposal. Special report

    International Nuclear Information System (INIS)

    Dau, G.J.; Williams, R.F.

    1976-09-01

    The results of this review, presented in the form of a functional description of high level waste management system, shows that technology is available to dispose of nuclear waste safely by several different processes. The most attractive alternative in terms of available technology and shortness of time to demonstrate it at commercial scale is a system that converts the waste to a solid by immobilizing the radioactive elements in a glass matrix. Brief comments are also given on international efforts in high level waste management and advanced disposal concepts

  4. Managing the nation's high-level radioactive waste: key issues and recommendations

    International Nuclear Information System (INIS)

    1981-07-01

    To date, no unified national plan has been adopted to develop and implement a comprehensive system of management and disposal of high-level radioactive waste in the United States. Growing public concern about this problem has resulted in a number of recent efforts to develop a national high-level waste management policy. The 96th Congress strove to resolve the central issues, but ultimately failed to pass legislation, partly because of disagreements about the appropriate role of states in the siting of repositories for military waste. Outside government, a number of organizations convened representatives of diverse groups concerned with national high-level radioactive waste management to seek agreement on the major elements of national policy. One such organization was RESOLVE, Center for Environmental Conflict Resolution, which in May 1981 was merged into The Conservation Foundation. RESOLVE convened Forum II, a series of discussions among representatives of environmental, industrial, governmental, and citizen interest groups, in 1981 specifically to address the issues blocking Congressional agreement on high-level waste policy. This report contains the recommendations which resulted from these deliberations. Reprocessing, interim storage, respository development, and licensing requirements are addressed. Federal, state, and public participation in decision making are also discussed

  5. Michigan high-level radioactive waste program. Technical progress report for 1985

    International Nuclear Information System (INIS)

    1986-01-01

    In 1985, five crystalline rock formations located in Michigan's Upper Peninsula were under consideration in the regional phase of the Department of Energy's (DOE) search for the site of the nation's second high-level radioactive waste repository. The Michigan Department of Public Health has been designated by the Governor as lead state agency in matters related to high-level radioactive waste (HLRW). Mr. Lee E. Jager, Chief of the Department's Bureau of Environmental and Occupational Health, has been designated as the state contact person in this matter, and the Bureau's Division of Radiological Health, Office of Radioactive Waste Management (ORWM), has been designated to provide staff support. Recognizing that adequate state involvement in the various aspects of the Federal high-level radioactive waste (HLRW) programs would require a range of expertise beyond the scope of any single state agency, Governor Blanchard established the High-Level Radioactive Waste Task Force in 1983. In support of the Task Force efforts concerning the implementation of its change, the Department negotiated and concluded an agreement with the DOE, under which federal funds are provided to support state HLRW activities. This report outlines state activities for the calendar year 1985, funded under that agreement

  6. Technical career opportunities in high-level radioactive waste management

    International Nuclear Information System (INIS)

    1993-01-01

    Technical career opportunities in high-level radioactive waste management are briefly described in the areas of: Hydrology; geology; biological sciences; mathematics; engineering; heavy equipment operation; and skilled labor and crafts

  7. A high-level power model for MPSoC on FPGA

    NARCIS (Netherlands)

    Piscitelli, R.; Pimentel, A.D.

    2011-01-01

    This paper presents a framework for high-level power estimation of multiprocessor systems-on-chip (MPSoC) architectures on FPGA. The technique is based on abstract execution profiles, called event signatures, and it operates at a higher level of abstraction than, e.g., commonly-used instruction-set

  8. Study on high-level waste geological disposal metadata model

    International Nuclear Information System (INIS)

    Ding Xiaobin; Wang Changhong; Zhu Hehua; Li Xiaojun

    2008-01-01

    This paper expatiated the concept of metadata and its researches within china and abroad, then explain why start the study on the metadata model of high-level nuclear waste deep geological disposal project. As reference to GML, the author first set up DML under the framework of digital underground space engineering. Based on DML, a standardized metadata employed in high-level nuclear waste deep geological disposal project is presented. Then, a Metadata Model with the utilization of internet is put forward. With the standardized data and CSW services, this model may solve the problem in the data sharing and exchanging of different data form A metadata editor is build up in order to search and maintain metadata based on this model. (authors)

  9. Unexpected patterns of admixture in German populations of Aedes japonicus japonicus (Diptera: Culicidae underscore the importance of human intervention.

    Directory of Open Access Journals (Sweden)

    Dorothee E Zielke

    Full Text Available The mosquito Aedes japonicus japonicus, originally restricted to temperate East Asia, is now widespread in North America and more recently has become established in Europe. To ascertain the putative number of separate introductions to Europe and examine patterns of expansion we analyzed the genetic makeup of Ae. j. japonicus populations from five cemeteries in North Rhine-Westphalia and Rhineland-Palatinate, two western German federal states, as well as of specimens from populations in Belgium, Switzerland, and Austria/Slovenia. To do so, we genotyped individual specimens at seven pre-existing polymorphic microsatellite loci and sequenced part of the nad4 mitochondrial locus. We found evidence of two different genotypic signatures associated with different nad4 mitochondrial haplotypes, indicating at least two genetically differentiated populations of Ae. j. japonicus in Europe (i.e. two distinct genotypes. Belgian, Swiss, and Austrian/Slovenian populations all share the same genotypic signature although they have become differentiated since isolation. Contrary to expectations, the German Ae. j. japonicus are not closely related to those in Belgium which are geographically nearest but are also highly inbred. German populations have a unique genotype but also evidence of mixing between the two genotypes. Also unexpectedly, the populations closest to the center of the German infestation had the highest levels of admixture indicating that separate introductions did not expand and merge but instead their expansion was driven by punctuated human-mediated transport. Critically, the resulting admixed populations have higher genetic diversity and appear invasive as indicated by their increased abundance and recent spread across western Germany.

  10. Fish Oil Supplementation Reduces Heart Levels of Interleukin-6 in Rats with Chronic Inflammation due to Epilepsy

    Directory of Open Access Journals (Sweden)

    Mariana Bocca Nejm

    2017-06-01

    Full Text Available Sudden unexpected death in epilepsy (SUDEP is a major cause of premature death related to epilepsy. The causes of SUDEP remain unknown, but cardiac arrhythmias and asphyxia have been suggested as a major mechanism of this event. Inflammation has been implicated in the pathogenesis of both epilepsy and ventricular arrhythmia, with interleukin-6 (IL-6 being recognized as a crucial orchestrator of inflammatory states. Our group previously reported that levels of IL-6 were increased in the hearts of epileptic rats. In this scenario, anti-inflammatory actions are among the beneficial effects of fish oil dietary supplementation. This investigation revealed that elevated levels of IL-6 in the heart were markedly reduced in epileptic rats that were treated in the long-term with fish oil, suggesting protective anti-inflammatory actions against dangerously high levels of IL-6. Based on these findings, our results suggest beneficial effects of long-term intake of fish oil in reducing the inflammation associated with chronic epilepsy.

  11. A proposed classification system for high-level and other radioactive wastes

    International Nuclear Information System (INIS)

    Kocher, D.C.; Croff, A.G.

    1987-06-01

    This report presents a proposal for quantitative and generally applicable risk-based definitions of high-level and other radioactive wastes. On the basis of historical descriptions and definitions of high-level waste (HLW), in which HLW has been defined in terms of its source as waste from reprocessing of spent nuclear fuel, we propose a more general definition based on the concept that HLW has two distinct attributes: HLW is (1) highly radioactive and (2) requires permanent isolation. This concept leads to a two-dimensional waste classification system in which one axis, related to ''requires permanent isolation,'' is associated with long-term risks from waste disposal and the other axis, related to ''highly radioactive,'' is associated with shorter-term risks due to high levels of decay heat and external radiation. We define wastes that require permanent isolation as wastes with concentrations of radionuclides exceeding the Class-C limits that are generally acceptable for near-surface land disposal, as specified in the US Nuclear Regulatory Commission's rulemaking 10 CFR Part 61 and its supporting documentation. HLW then is waste requiring permanent isolation that also is highly radioactive, and we define ''highly radioactive'' as a decay heat (power density) in the waste greater than 50 W/m 3 or an external radiation dose rate at a distance of 1 m from the waste greater than 100 rem/h (1 Sv/h), whichever is the more restrictive. This proposal also results in a definition of Transuranic (TRU) Waste and Equivalent as waste that requires permanent isolation but is not highly radioactive and a definition of low-level waste (LLW) as waste that does not require permanent isolation without regard to whether or not it is highly radioactive

  12. High levels of natural radionuclides in a deep-sea infaunal xenophyophore

    Energy Technology Data Exchange (ETDEWEB)

    Swinbanks, D D; Shirayama, Y

    1986-03-27

    The paper concerns the high levels of natural radionuclides in a deep-sea infaunal xenophyophore from the Izu-Ogasawara Trench. Measured /sup 210/Po activities and barium contents of various parts of Occultammina profunda and the surrounding sediment are given, together with their estimated /sup 210/Pb and /sup 226/Ra activities. The data suggest that xenophyphores are probably subject to unusually high levels of natural radiation.

  13. Unexpected high diversity of galling insects in the Amazonian upper canopy: the savanna out there.

    Science.gov (United States)

    Julião, Genimar R; Venticinque, Eduardo M; Fernandes, G Wilson; Price, Peter W

    2014-01-01

    A relatively large number of studies reassert the strong relationship between galling insect diversity and extreme hydric and thermal status in some habitats, and an overall pattern of a greater number of galling species in the understory of scleromorphic vegetation. We compared galling insect diversity in the forest canopy and its relationship with tree richness among upland terra firme, várzea, and igapó floodplains in Amazonia, Brazil. The soils of these forest types have highly different hydric and nutritional status. Overall, we examined the upper layer of 1,091 tree crowns. Galling species richness and abundance were higher in terra firme forests compared to várzea and igapó forests. GLM-ANCOVA models revealed that the number of tree species sampled in each forest type was determinant in the gall-forming insect diversity. The ratio between galling insect richness and number of tree species sampled (GIR/TSS ratio) was higher in the terra firme forest and in seasonally flooded igapó, while the várzea presented the lowest GIR/TSS ratio. In this study, we recorded unprecedented values of galling species diversity and abundance per sampling point. The GIR/TSS ratio from várzea was approximately 2.5 times higher than the highest value of this ratio ever reported in the literature. Based on this fact, we ascertained that várzea and igapó floodplain forests (with lower GIA and GIR), together with the speciose terra firme galling community emerge as the gall diversity apex landscape among all biogeographic regions already investigated. Contrary to expectation, our results also support the "harsh environment hypothesis", and unveil the Amazonian upper canopy as similar to Mediterranean vegetation habitats, hygrothermically stressed environments with leaf temperature at lethal limits and high levels of leaf sclerophylly.

  14. Unexpected high diversity of galling insects in the Amazonian upper canopy: the savanna out there.

    Directory of Open Access Journals (Sweden)

    Genimar R Julião

    Full Text Available A relatively large number of studies reassert the strong relationship between galling insect diversity and extreme hydric and thermal status in some habitats, and an overall pattern of a greater number of galling species in the understory of scleromorphic vegetation. We compared galling insect diversity in the forest canopy and its relationship with tree richness among upland terra firme, várzea, and igapó floodplains in Amazonia, Brazil. The soils of these forest types have highly different hydric and nutritional status. Overall, we examined the upper layer of 1,091 tree crowns. Galling species richness and abundance were higher in terra firme forests compared to várzea and igapó forests. GLM-ANCOVA models revealed that the number of tree species sampled in each forest type was determinant in the gall-forming insect diversity. The ratio between galling insect richness and number of tree species sampled (GIR/TSS ratio was higher in the terra firme forest and in seasonally flooded igapó, while the várzea presented the lowest GIR/TSS ratio. In this study, we recorded unprecedented values of galling species diversity and abundance per sampling point. The GIR/TSS ratio from várzea was approximately 2.5 times higher than the highest value of this ratio ever reported in the literature. Based on this fact, we ascertained that várzea and igapó floodplain forests (with lower GIA and GIR, together with the speciose terra firme galling community emerge as the gall diversity apex landscape among all biogeographic regions already investigated. Contrary to expectation, our results also support the "harsh environment hypothesis", and unveil the Amazonian upper canopy as similar to Mediterranean vegetation habitats, hygrothermically stressed environments with leaf temperature at lethal limits and high levels of leaf sclerophylly.

  15. Unexpected Molecular Sieving Properties of Zeolitic Imidazolate Framework-8

    KAUST Repository

    Zhang, Chen; Lively, Ryan P.; Zhang, Ke; Johnson, Justin R.; Karvan, Oguz; Koros, William J.

    2012-01-01

    We studied molecular sieving properties of zeolitic imidazolate framework-8 (ZIF-8) by estimating the thermodynamically corrected diffusivities of probe molecules at 35 °C. From helium (2.6 Å) to iso-C 4H 10 (5.0 Å), the corrected diffusivity drops 14 orders of magnitude. Our results further suggest that the effective aperture size of ZIF-8 for molecular sieving is in the range of 4.0 to 4.2 Å, which is significantly larger than the XRD-derived value (3.4 Å) and between the well-known aperture size of zeolite 4A (3.8 Å) and 5A (4.3 Å). Interestingly, because of aperture flexibility, the studied C 4 hydrocarbon molecules that are larger than this effective aperture size still adsorb in the micropores of ZIF-8 with kinetic selectivities for iso-C 4H 8/iso-C 4H 10 of 180 and n-C 4H 10/iso-C 4H 10 of 2.5 × 10 6. These unexpected molecular sieving properties open up new opportunities for ZIF materials for separations that cannot be economically achieved by traditional microporous adsorbents such as synthetic zeolites. © 2012 American Chemical Society.

  16. Unexpected Molecular Sieving Properties of Zeolitic Imidazolate Framework-8

    KAUST Repository

    Zhang, Chen

    2012-08-16

    We studied molecular sieving properties of zeolitic imidazolate framework-8 (ZIF-8) by estimating the thermodynamically corrected diffusivities of probe molecules at 35 °C. From helium (2.6 Å) to iso-C 4H 10 (5.0 Å), the corrected diffusivity drops 14 orders of magnitude. Our results further suggest that the effective aperture size of ZIF-8 for molecular sieving is in the range of 4.0 to 4.2 Å, which is significantly larger than the XRD-derived value (3.4 Å) and between the well-known aperture size of zeolite 4A (3.8 Å) and 5A (4.3 Å). Interestingly, because of aperture flexibility, the studied C 4 hydrocarbon molecules that are larger than this effective aperture size still adsorb in the micropores of ZIF-8 with kinetic selectivities for iso-C 4H 8/iso-C 4H 10 of 180 and n-C 4H 10/iso-C 4H 10 of 2.5 × 10 6. These unexpected molecular sieving properties open up new opportunities for ZIF materials for separations that cannot be economically achieved by traditional microporous adsorbents such as synthetic zeolites. © 2012 American Chemical Society.

  17. High-level waste processing and disposal

    International Nuclear Information System (INIS)

    Crandall, J.L.; Krause, H.; Sombret, C.; Uematsu, K.

    1984-11-01

    Without reprocessing, spent LWR fuel itself is generally considered an acceptable waste form. With reprocessing, borosilicate glass canisters, have now gained general acceptance for waste immobilization. The current first choice for disposal is emplacement in an engineered structure in a mined cavern at a depth of 500-1000 meters. A variety of rock types are being investigated including basalt, clay, granite, salt, shale, and volcanic tuff. This paper gives specific coverage to the national high level waste disposal plans for France, the Federal Republic of Germany, Japan and the United States. The French nuclear program assumes prompt reprocessing of its spent fuels, and France has already constructed the AVM. Two larger borosilicate glass plants are planned for a new French reprocessing plant at La Hague. France plans to hold the glass canisters in near-surface storage for a forty to sixty year cooling period and then to place them into a mined repository. The FRG and Japan also plan reprocessing for their LWR fuels. Both are currently having some fuel reprocessed by France, but both are also planning reprocessing plants which will include waste vitrification facilities. West Germany is now constructing the PAMELA Plant at Mol, Belgium to vitrify high level reprocessing wastes at the shutdown Eurochemic Plant. Japan is now operating a vitrification mockup test facility and plans a pilot plant facility at the Tokai reprocessing plant by 1990. Both countries have active geologic repository programs. The United State program assumes little LWR fuel reprocessing and is thus primarily aimed at direct disposal of spent fuel into mined repositories. However, the US have two borosilicate glass plants under construction to vitrify existing reprocessing wastes

  18. Status of the high-level nuclear waste disposal program in Japan

    International Nuclear Information System (INIS)

    Uematsu, K.

    1985-01-01

    The Japan Atomic Energy Commission (JAEC) initiated a high-level radioactive waste disposal program in 1976. Since then, the Advisory Committee on Radioactive Waste Management of JAEC has revised the program twice. The latest revision was issued in 1984. The committee recommended a four-phase program and the last phase calls for the beginning of emplacement of the high-level nuclear waste into a selected repository in the Year 2000. The first phase is already completed, and the second phase of this decade calls for the selection of a candidate disposal site and the conducting of the RandD of waste disposal in an underground research laboratory and in a hot test facility. This paper covers the current status of the high-level nuclear waste disposal program in Japan

  19. Performance of high level waste forms and engineered barriers under repository conditions

    International Nuclear Information System (INIS)

    1991-02-01

    The IAEA initiated in 1977 a co-ordinated research programme on the ''Evaluation of Solidified High-Level Waste Forms'' which was terminated in 1983. As there was a continuing need for international collaboration in research on solidified high-level waste form and spent fuel, the IAEA initiated a new programme in 1984. The new programme, besides including spent fuel and SYNROC, also placed greater emphasis on the effect of the engineered barriers of future repositories on the properties of the waste form. These engineered barriers included containers, overpacks, buffer and backfill materials etc. as components of the ''near-field'' of the repository. The Co-ordinated Research Programme on the Performance of High-Level Waste Forms and Engineered Barriers Under Repository Conditions had the objectives of promoting the exchange of information on the experience gained by different Member States in experimental performance data and technical model evaluation of solidified high level waste forms, components of the waste package and the complete waste management system under conditions relevant to final repository disposal. The programme includes studies on both irradiated spent fuel and glass and ceramic forms as the final solidified waste forms. The following topics were discussed: Leaching of vitrified high-level wastes, modelling of glass behaviour in clay, salt and granite repositories, environmental impacts of radionuclide release, synroc use for high--level waste solidification, leachate-rock interactions, spent fuel disposal in deep geologic repositories and radionuclide release mechanisms from various fuel types, radiolysis and selective leaching correlated with matrix alteration. Refs, figs and tabs

  20. NOS CO-OPS Water Level Data, Verified, High Low

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset has verified (quality-controlled), daily, high low water level (tide) data from NOAA NOS Center for Operational Oceanographic Products and Services...

  1. Permitting plan for the high-level waste interim storage

    International Nuclear Information System (INIS)

    Deffenbaugh, M.L.

    1997-01-01

    This document addresses the environmental permitting requirements for the transportation and interim storage of solidified high-level waste (HLW) produced during Phase 1 of the Hanford Site privatization effort. Solidified HLW consists of canisters containing vitrified HLW (glass) and containers that hold cesium separated during low-level waste pretreatment. The glass canisters and cesium containers will be transported to the Canister Storage Building (CSB) in a U.S. Department of Energy (DOE)-provided transportation cask via diesel-powered tractor trailer. Tri-Party Agreement (TPA) Milestone M-90 establishes a new major milestone, and associated interim milestones and target dates, governing acquisition and/or modification of facilities necessary for: (1) interim storage of Tank Waste Remediation Systems (TWRS) immobilized HLW (IHLW) and other canistered high-level waste forms; and (2) interim storage and disposal of TWRS immobilized low-activity tank waste (ILAW). An environmental requirements checklist and narrative was developed to identify the permitting path forward for the HLW interim storage (HLWIS) project (See Appendix B). This permitting plan will follow the permitting logic developed in that checklist

  2. The Estuary Guide. Level 3: High School. Draft.

    Science.gov (United States)

    Alexander, Glen; And Others

    Estuaries are marine systems that serve as nurseries for animals, links in the migratory pathways, and habitat for a complex community of organisms. This curriculum guide intended for use at the high school level seeks to teach what estuaries are; provide opportunities to practice decision-making that affects estuaries; and encourage students to…

  3. Evaluation of strategies for end storage of high-level reactor fuel

    International Nuclear Information System (INIS)

    2001-01-01

    This report evaluates a national strategy for end-storage of used high-level reactor fuel from the research reactors at Kjeller and in Halden. This strategy presupposes that all the important phases in handling the high-level material, including temporary storage and deposition, are covered. The quantity of spent fuel from Norwegian reactors is quite small. In addition to the technological issues, ethical, environmental, safety and economical requirements are emphasized

  4. Development of a test system for high level liquid waste partitioning

    OpenAIRE

    Duan Wu H.; Chen Jing; Wang Jian C.; Wang Shu W.; Wang Xing H.

    2015-01-01

    The partitioning and transmutation strategy has increasingly attracted interest for the safe treatment and disposal of high level liquid waste, in which the partitioning of high level liquid waste is one of the critical technical issues. An improved total partitioning process, including a tri-alkylphosphine oxide process for the removal of actinides, a crown ether strontium extraction process for the removal of strontium, and a calixcrown ether cesium extra...

  5. On the unexpected oscillation of the total cross section for excitation in He2+ + H collisions

    International Nuclear Information System (INIS)

    Schultz, D.R.; Reinhold, C.O.; Krstic, P.S.

    1996-01-01

    Recent calculations and measurements have revealed unexpected oscillations of the total cross section for excitation in low- to intermediate-energy He 2+ + H collisions. A physical explanation of this behavior is given here stemming from analysis of classical trajectory Monte Carlo simulations, molecular orbital close coupling calculations, and solution of the time-dependent Schroedinger equation on a numerical lattice. These results indicate that the observed behavior should be characteristic of a wide range of reactions in ion-atom collisions

  6. High-level radioactive waste in Canada. Background paper

    International Nuclear Information System (INIS)

    Fawcett, R.

    1993-11-01

    The disposal of radioactive waste is one of the most challenging environmental problems facing Canada today. Since the Second World War, when Canadian scientists first started to investigate nuclear reactions, there has been a steady accumulation of such waste. Research reactors built in the early postwar years produced small amounts of radioactive material but the volume grew steadily as the nuclear power reactors constructed during the 1960s and 1970s began to spawn used fuel bundles. Although this radioactive refuse has been safely stored for the short term, no permanent disposal system has yet been fully developed and implemented. Canada is not alone in this regard. A large number of countries use nuclear power reactors but none has yet put in place a method for the long-term disposal of the radioactive waste. Scientists and engineers throughout the world are investigating different possibilities; however, enormous difficulties remain. In Canada, used fuel bundles from nuclear reactors are defined as high-level waste; all other waste created at different stages in the nuclear fuel cycle is classified as low-level. Although disposal of low-level waste is an important issue, it is a more tractable problem than the disposal of high-level waste, on which this paper will concentrate. The paper discusses the nuclear fuel waste management program in Canada, where a long-term disposal plan has been under development by scientists and engineers over the past 15 years, but will not be completed for some time. Also discussed are responses to the program by parliamentary committees and aboriginal and environmental groups, and the work in the area being conducted in other countries. (author). 1 tab

  7. High-level radioactive waste in Canada. Background paper

    Energy Technology Data Exchange (ETDEWEB)

    Fawcett, R [Library of Parliament, Ottawa, ON (Canada). Science and Technology Div.

    1993-11-01

    The disposal of radioactive waste is one of the most challenging environmental problems facing Canada today. Since the Second World War, when Canadian scientists first started to investigate nuclear reactions, there has been a steady accumulation of such waste. Research reactors built in the early postwar years produced small amounts of radioactive material but the volume grew steadily as the nuclear power reactors constructed during the 1960s and 1970s began to spawn used fuel bundles. Although this radioactive refuse has been safely stored for the short term, no permanent disposal system has yet been fully developed and implemented. Canada is not alone in this regard. A large number of countries use nuclear power reactors but none has yet put in place a method for the long-term disposal of the radioactive waste. Scientists and engineers throughout the world are investigating different possibilities; however, enormous difficulties remain. In Canada, used fuel bundles from nuclear reactors are defined as high-level waste; all other waste created at different stages in the nuclear fuel cycle is classified as low-level. Although disposal of low-level waste is an important issue, it is a more tractable problem than the disposal of high-level waste, on which this paper will concentrate. The paper discusses the nuclear fuel waste management program in Canada, where a long-term disposal plan has been under development by scientists and engineers over the past 15 years, but will not be completed for some time. Also discussed are responses to the program by parliamentary committees and aboriginal and environmental groups, and the work in the area being conducted in other countries. (author). 1 tab.

  8. Title: High-level cefotaxime-resistant Proteus mirabilis strain isolated ...

    African Journals Online (AJOL)

    oaca

    High-level cefotaxime-resistant Proteus mirabilis strain isolated from a Tunisian .... UV- visible) at 37°C. Specific activity is calculated on depending of. Ross and ..... Performance standards for antimicrobial susceptibility testing;. Seventeenth ...

  9. Risk comparison of different treatment and disposal strategies of high level liquid radioactive waste

    International Nuclear Information System (INIS)

    Fang Dong

    1997-01-01

    The risk of different treatment and disposal strategies of high level liquid radioactive waste from spent fuel reprocessing is estimated and compared. The conclusions obtained are that risk difference from these strategies is very small and high level liquid waste can be reduced to middle and low level waste, if the decontamination factor for 99 Tc is large enough, which is the largest risk contributor in the high level radioactive waste from spent fuel reprocessing. It is also shown that the risk of high level radioactive waste could be reduced by the technical strategy of combining partitioning and transmutation

  10. Unexpected decline in tuberculosis cases coincident with economic recession -- United States, 2009

    Directory of Open Access Journals (Sweden)

    Winston Carla A

    2011-11-01

    Full Text Available Abstract Background Since 1953, through the cooperation of state and local health departments, the U.S. Centers for Disease Control and Prevention (CDC has collected information on incident cases of tuberculosis (TB disease in the United States. In 2009, TB case rates declined -11.4%, compared to an average annual -3.8% decline since 2000. The unexpectedly large decline raised concerns that TB cases may have gone unreported. To address the unexpected decline, we examined trends from multiple sources on TB treatment initiation, medication sales, and laboratory and genotyping data on culture-positive TB. Methods We analyzed 142,174 incident TB cases reported to the U. S. National Tuberculosis Surveillance System (NTSS during January 1, 2000-December 31, 2009; TB control program data from 59 public health reporting areas; self-reported data from 50 CDC-funded public health laboratories; monthly electronic prescription claims for new TB therapy prescriptions; and complete genotyping results available for NTSS cases. Accounting for prior trends using regression and time-series analyses, we calculated the deviation between observed and expected TB cases in 2009 according to patient and clinical characteristics, and assessed at what point in time the deviation occurred. Results The overall deviation in TB cases in 2009 was -7.9%, with -994 fewer cases reported than expected (P Conclusions Our assessments show that the decline in reported TB was not an artifact of changes in surveillance methods; rather, similar declines were found through multiple data sources. While the steady decline of TB cases before 2009 suggests ongoing improvement in TB control, we were not able to identify any substantial change in TB control activities or TB transmission that would account for the abrupt decline in 2009. It is possible that other multiple causes coincident with economic recession in the United States, including decreased immigration and delayed access to

  11. Safety of geologic disposal of high level radioactive waste

    International Nuclear Information System (INIS)

    Zaitsu, Tomohisa; Ishiguro, Katsuhiko; Masuda, Sumio

    1992-01-01

    This article introduces current concepts of geologic disposal of high level radioactive waste and its safety. High level radioactive waste is physically stabilized by solidifying it in a glass form. Characteristics of deep geologic layer are presented from the viewpoint of geologic disposal. Reconstruction of multi-barrier system receives much attention to secure the safety of geologic disposal. It is important to research performance assessment of multi-barrier system for preventing dissolution or transfer of radionuclides into the ground water. Physical and chemical modeling for the performance assessment is outlined in the following terms: (1) chemical property of deep ground water, (2) geochemical modeling of artificial barrier spatial water, (3) hydrology of deep ground water, (4) hydrology of the inside of artificial barrier, and (5) modeling of radionuclide transfer from artificial barrier. (N.K.)

  12. The expected and unexpected benefits of dispensing the exact number of pills.

    Science.gov (United States)

    Treibich, Carole; Lescher, Sabine; Sagaon-Teyssier, Luis; Ventelou, Bruno

    2017-01-01

    From November 2014 to November 2015, an experiment in French community pharmacies replaced traditional pre-packed boxes by per-unit dispensing of pills in the exact numbers prescribed, for 14 antibiotics. A cluster randomised control trial was carried out in 100 pharmacies. 75 pharmacies counted out the medication by units (experimental group), the other 25 providing the treatment in the existing pharmaceutical company boxes (control group). Data on patients under the two arms were compared to assess the environmental, economic and health effects of this change in drug dispensing. In particular, adherence was measured indirectly by comparing the number of pills left at the end of the prescribed treatment. Out of the 1185 patients included during 3 sessions of 4 consecutive weeks each, 907 patients experimented the personalized delivery and 278 were assigned to the control group, consistent with a 1/3 randomization-rate at the pharmacy level. 80% of eligible patients approved of the per-unit dispensing of their treatment. The initial packaging of the drugs did not match with the prescription in 60% of cases and per-unit dispensing reduced by 10% the number of pills supplied. 13.1% of patients declared that they threw away pills residuals instead of recycling-no differences between groups. Finally, per-unit dispensing appeared to improve adherence to antibiotic treatment (marginal effect 0.21, IC 95, 0.14-0.28). Supplying antibiotics per unit is not only beneficial in terms of a reduced number of pills to reimburse or for the environment (less pills wasted and non-recycled), but also has a positive and unexpected impact on adherence to treatment, and thus on both individual and public health.

  13. Studies of ATM for ATLAS high-level triggers

    CERN Document Server

    Bystrický, J; Huet, M; Le Dû, P; Mandjavidze, I D

    2001-01-01

    This paper presents some of the conclusions of our studies on asynchronous transfer mode (ATM) and fast Ethernet in the ATLAS level-2 trigger pilot project. We describe the general concept and principles of our data-collection and event-building scheme that could be transposed to various experiments in high-energy and nuclear physics. To validate the approach in view of ATLAS high-level triggers, we assembled a testbed composed of up to 48 computers linked by a 7.5-Gbit/s ATM switch. This modular switch is used as a single entity or is split into several smaller interconnected switches. This allows study of how to construct a large network from smaller units. Alternatively, the ATM network can be replaced by fast Ethernet. We detail the operation of the system and present series of performance measurements made with event-building traffic pattern. We extrapolate these results to show how today's commercial networking components could be used to build a 1000-port network adequate for ATLAS needs. Lastly, we li...

  14. Representation and Integration: Combining Robot Control, High-Level Planning, and Action Learning

    DEFF Research Database (Denmark)

    Petrick, Ronald; Kraft, Dirk; Mourao, Kira

    We describe an approach to integrated robot control, high-level planning, and action effect learning that attempts to overcome the representational difficulties that exist between these diverse areas. Our approach combines ideas from robot vision, knowledgelevel planning, and connectionist machine......-level action specifications, suitable for planning, from a robot’s interactions with the world. We present a detailed overview of our approach and show how it supports the learning of certain aspects of a high-level lepresentation from low-level world state information....... learning, and focuses on the representational needs of these components.We also make use of a simple representational unit called an instantiated state transition fragment (ISTF) and a related structure called an object-action complex (OAC). The goal of this work is a general approach for inducing high...

  15. A framework for the definition of variants of high-level Petri nets

    DEFF Research Database (Denmark)

    Kindler, Ekkart; Petrucci, Laure

    2009-01-01

    with data-type specific issues, which often blocks the view for the really relevant parts. Even worse, supposedly simpler versions of high-level nets often are more difficult to define than high-level nets in general. This paper introduces the concepts and the mathematical tools to ease the definition...

  16. Fatty acid oxidation disorders as primary cause of sudden and unexpected death in infants and young children

    DEFF Research Database (Denmark)

    Banner, Jytte; Kølvraa, S; Gregersen, N

    1997-01-01

    Disorders of fatty acid metabolism are known to be responsible for cases of sudden and unexpected death in infancy. At least 14 disorders are known at present. 120 cases of sudden infant death syndrome (SIDS) had been examined for a prevalent mutation (G985) causing medium chain acyl Co......A dehydrogenase deficiency, which is inherited in an autosomal recessive mode. No over-representation of either homozygous or heterozygous cases was found....

  17. Midwestern High-Level Radioactive Waste Transportation Project

    International Nuclear Information System (INIS)

    1993-01-01

    On February 17,1989, the Midwestern Office of The Council of State Governments and the US Department of Energy entered into a cooperative agreement authorizing the initiation of the Midwestern High-Level Radioactive Waste Transportation Project. The transportation project continued to receive funding from DOE through amendments to the original cooperative agreement, with December 31, 1993, marking the end of the initial 5-year period. This progress report reflects the work completed by the Midwestern Office from February 17,1989, through December 31,1993. In accordance with the scopes of work governing the period covered by this report, the Midwestern Office of The Council of State Governments has worked closely with the Midwestern High-Level Radioactive Waste Committee. Project staff have facilitated all eight of the committee's meetings and have represented the committee at meetings of DOE's Transportation Coordination Group (TCG) and Transportation External Coordination Working Group (TEC/WG). Staff have also prepared and submitted comments on DOE activities on behalf of the committee. In addition to working with the committee, project staff have prepared and distributed 20 reports, including some revised reports (see Attachment 1). Staff have also developed a library of reference materials for the benefit of committee members, state officials, and other interested parties. To publicize the library, and to make it more accessible to potential users, project staff have prepared and distributed regular notices of resource availability

  18. A high-speed DAQ framework for future high-level trigger and event building clusters

    International Nuclear Information System (INIS)

    Caselle, M.; Perez, L.E. Ardila; Balzer, M.; Dritschler, T.; Kopmann, A.; Mohr, H.; Rota, L.; Vogelgesang, M.; Weber, M.

    2017-01-01

    Modern data acquisition and trigger systems require a throughput of several GB/s and latencies of the order of microseconds. To satisfy such requirements, a heterogeneous readout system based on FPGA readout cards and GPU-based computing nodes coupled by InfiniBand has been developed. The incoming data from the back-end electronics is delivered directly into the internal memory of GPUs through a dedicated peer-to-peer PCIe communication. High performance DMA engines have been developed for direct communication between FPGAs and GPUs using 'DirectGMA (AMD)' and 'GPUDirect (NVIDIA)' technologies. The proposed infrastructure is a candidate for future generations of event building clusters, high-level trigger filter farms and low-level trigger system. In this paper the heterogeneous FPGA-GPU architecture will be presented and its performance be discussed.

  19. Development of cermets for high-level radioactive waste fixation

    International Nuclear Information System (INIS)

    Aaron, W.S.; Quinby, T.C.; Kobisk, E.H.

    1979-01-01

    A method is currently under development for the solidification and fixation of commercial and defense high-level radioactive wastes in the form of ceramic particles encapsulated by metal, i.e., a cermet. The chemical and physical processing techniques which have been developed and the properties of the resulting cermet bodies are described in this paper. These cermets have the advantages of high thermal conductivity and low leach rates

  20. The tracking of high level waste shipments-TRANSCOM system

    International Nuclear Information System (INIS)

    Johnson, P.E.; Joy, D.S.; Pope, R.B.

    1995-01-01

    The TRANSCOM (transportation tracking and communication) system is the U.S. Department of Energy's (DOE's) real-time system for tracking shipments of spent fuel, high-level wastes, and other high-visibility shipments of radioactive material. The TRANSCOM system has been operational since 1988. The system was used during FY1993 to track almost 100 shipments within the US.DOE complex, and it is accessed weekly by 10 to 20 users