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Sample records for undetectable ctc status

  1. Cooperative Tagging Center (CTC)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Cooperative Tagging Center (CTC) began as the Cooperative Game Fish Tagging Program (GTP) at Woods Hole Oceanographic Institute (WHOI) in 1954. The GTP was...

  2. How to read and report CTC

    International Nuclear Information System (INIS)

    Neri, Emanuele; Mang, Thomas; Hellstrom, Mikael; Mantarro, Annalisa; Faggioni, Lorenzo; Bartolozzi, Carlo

    2013-01-01

    Owing to encouraging results achieved in the clinical practice, CT colonography (CTC) is being increasingly employed for the examination of the whole colon and rectum and is quickly becoming a widely accepted diagnostic technique that is replacing double contrast barium enema and appears a promising tool for colorectal cancer screening as well. The increasing number of symptomatic and asymptomatic patients undergoing CTC for both evaluation of symptoms and colorectal cancer screening, along with the growing availability of CTC facilities in most healthcare departments and imaging centres, requires that a sufficient number of radiologists be adequately trained in performing and interpreting CTC studies. Indeed, optimal performance of CTC depends on a number of factors, including the quality of colonic preparation (e.g. laxative bowel cleansing and optimised colonic distension), the CTC image acquisition protocol used, and reading approach and specific skills of radiologists for correct detection and interpretation of colonic findings. Consequently, dedicated training and expertise is key to obtain high sensitivity in lesion detection and reduce the number of false positives, thus ensuring an optimal clinical management of patients. To this purpose, dedicated training programmes are essential to teach and standardise not only the approach to CTC reading, but also reporting of colonic findings

  3. Computed tomographic colonography (CTC); colorectal cancer diagnosis with CTC in an Auckland population

    International Nuclear Information System (INIS)

    Moore, Helen; Dodd, Nicholas

    2013-01-01

    To determine the sensitivity of computed tomographic colonography (CTC) in the detection of colorectal cancer in our population and evaluate the reasons why these lesions may be missed on CTC. All patients who underwent CTC in the 65-month period from 1 January 2004 to 1 July 2009 were included in the analysis. Demographic data and CTC findings were recorded, according to the CT Colonography Reporting and Data System. Data were cross-matched with the National Cancer Registry results for colorectal cancer cases between 1 January 2004 and 1 October 2009, 3 months longer to include any delayed diagnoses. There were 2026 consecutive CTC patients, comprising 52.6% female, average age of 60 years; range 19–87. Approximately 84% were symptomatic. There were 45 confirmed colorectal cancers among this patient group in the National Cancer Registry during the relevant time period compared with 43 suspected cancers on CTC, giving a miss rate of 2 of 45, or 4.4%. The sensitivity of 95% for CTC in the detection of colorectal cancer compares favourably with the published national and international data.

  4. CTC Sentinel. Volume 9, Issue 3

    Science.gov (United States)

    2016-03-01

    for the Caliphate,” CTC Sentinel 8:8 (2015). 28 Nicolas Beau, “Syrte, une cinquantaine de français aux cotés de Daech,” MondeAfrique, February 12...scale.”2 Earlier this month, Assistant Commissioner Mark Rowley, who oversees counterterrorism efforts for the London Metropoli- tan Police, warned

  5. CT colonography: current status in Europe and future perspectives

    International Nuclear Information System (INIS)

    Lefere, P.; Gryspeerdt, S.; Yoshida, H.

    2007-01-01

    In this article, we review the current status of CT colonography (CTC) in Europe and future perspectives of CTC including fecal tagging and CAD. There are several large multi-centre studies that have been initiated. Fecal tagging has gradually become a prerequisite to perform state-of-the-art CTC. However, CAD for fecal-tagging CTC remains a subject for future research. (orig.)

  6. Mechanisms of CTC Biomarkers in Breast Cancer Brain Metastasis

    Science.gov (United States)

    2015-10-01

    Department of the Army position, policy or decision unless so designated by other documentation. REPORT DOCUMENTATION PAGE Form Approved OMB No...patterns were noticeable up to 10-week analysis endpoint (Figure 1A). Of note, Notch1+/HPSE- CTC subsets generated 3D CTC macro -mammospheres (>5...9 days. Estrogen pellet (0.72mg; 90 day release; Innovative Research of America)(16) was subcutaneously implanted behind the neck of each mouse

  7. Impact of Undetected Comorbidity on Treatment and Outcomes of Breast Cancer

    Directory of Open Access Journals (Sweden)

    Robert I. Griffiths

    2014-01-01

    Full Text Available Preexisting comorbidity adversely impacts breast cancer treatment and outcomes. We examined the incremental impact of comorbidity undetected until cancer. We followed breast cancer patients in SEER-Medicare from 12 months before to 84 months after diagnosis. Two comorbidity indices were constructed: the National Cancer Institute index, using 12 months of claims before cancer, and a second index for previously undetected conditions, using three months after cancer. Conditions present in the first were excluded from the second. Overall, 6,184 (10.1% had ≥1 undetected comorbidity. Chronic obstructive pulmonary disease (38% was the most common undetected condition. In multivariable analyses that adjusted for comorbidity detected before cancer, older age, later stage, higher grade, and poor performance status all were associated with higher odds of ≥1 undetected comorbidity. In stage I–III cancer, undetected comorbidity was associated with lower adjusted odds of receiving adjuvant chemotherapy (Odds Ratio (OR = 0.81, 95% Confidence Interval (CI 0.73–0.90, P<0.0001; OR=0.38, 95% CI 0.30–0.49, P<0.0001; index score 1 or ≥2, respectively, and with increased mortality (Hazard Ratio (HR = 1.45, 95% CI 1.38–1.53, P<0.0001; HR=2.38, 95% CI 2.18–2.60, P<0.0001; index score 1 or ≥2. Undetected comorbidity is associated with less aggressive treatment and higher mortality in breast cancer.

  8. CTC Sentinel, Volume 9, Issue 1, January 2016

    Science.gov (United States)

    2016-01-01

    off digital media more gener- ally. But it’s changing all the time. New apps, new encryption. CTC: Are you calling here in the UK, like the FBI and...as 30 million people across West and Central Africa. Although the Peul are known as nomadic herders, they in fact comprise a heterogeneous group

  9. Determinants for undetected dementia and late-life depression.

    Science.gov (United States)

    Chen, Ruoling; Hu, Zhi; Chen, Ruo-Li; Ma, Ying; Zhang, Dongmei; Wilson, Kenneth

    2013-09-01

    Determinants for undetected dementia and late-life depression have been not well studied. To investigate risk factors for undetected dementia and depression in older communities. Using the method of the 10/66 algorithm, we interviewed a random sample of 7072 participants aged ≥60 years in six provinces of China during 2007-2011. We documented doctor-diagnosed dementia and depression in the interview. Using the validated 10/66 algorithm we diagnosed dementia (n = 359) and depression (n = 328). We found that 93.1% of dementia and 92.5% of depression was undetected. Both undetected dementia and depression were significantly associated with low levels of education and occupation, and living in a rural area. The risk of undetected dementia was also associated with 'help available when needed', and inversely, with a family history of mental illness and having functional impairment. Undetected depression was significantly related to female gender, low income, having more children and inversely with having heart disease. Older adults in China have high levels of undetected dementia and depression. General socioeconomic improvement, associated with mental health education, targeting high-risk populations are likely to increase detection of dementia and depression in older adults, providing a backdrop for culturally acceptable service development.

  10. Lactobacillus salivarius CTC2197 Prevents Salmonella enteritidis Colonization in Chickens

    OpenAIRE

    Pascual, Mònica; Hugas, Marta; Badiola, Jose Ignacio; Monfort, Josep Maria; Garriga, Margarita

    1999-01-01

    A rifampin-resistant Lactobacillus salivarius strain, CTC2197, was assessed as a probiotic in poultry, by studying its ability to prevent Salmonella enteritidis C-114 colonization in chickens. When the probiotic strain was dosed by oral gavage together with S. enteritidis C-114 directly into the proventriculus in 1-day-old Leghorn chickens, the pathogen was completely removed from the birds after 21 days. The same results were obtained when the probiotic strain was also administered through t...

  11. CTC Sentinel. Volume 5, Issue 11-12, November 2012

    Science.gov (United States)

    2012-11-01

    Price of Defiance,” The National, October 18, 2012. 13 Be they military in the case of Dariya, or adjacent to Alawite-populated towns and villages...business occurred in late May 2012 against the Mexican subsidiary of Pepsico snack and beverage company, Sabritas. The attack was viewed as the...point) MAJ Bryan price , ph.D. Director, CTC CONTACT Combating Terrorism Center U.s. Military Academy 607 Cullum Road, Lincoln Hall West point, NY 10996

  12. CTC Sentinel. Volume 6, Issue 9. September 2013

    Science.gov (United States)

    2013-09-01

    central government’s control and militants’ ability—and willingness—to quietly blend in.38 A security official in Hadramawt explained the group’s...safari.”17 8 Secunder Kermani, “Drone Victim’s Somalia Visits Probed,” BBC, May 30, 2013. 9 Personal interview, Tam Hussein, community worker who...shared vision of the Center products like the CTC Sentinel could not be produced. If you are interested in learning more about how to support the

  13. CTC Sentinel. Volume 9, Issue 2, February 2016

    Science.gov (United States)

    2016-06-02

    Islamic State side. See Derek Henry Flood: “The Islamic State Raises Its Black Flag Over The Caucasus,” CTC Sentinel 8:6 (2015): pp. 1-4. Dr. Guido...Qalamun,” [Hezbollah Holds Funeral for Child Killed in Al-Qalamun], Al-Araby Al-Jadid, April 28, 2015. 2 Lin Jenkins , “Isis video shows killing of

  14. A robust nonparametric method for quantifying undetected extinctions.

    Science.gov (United States)

    Chisholm, Ryan A; Giam, Xingli; Sadanandan, Keren R; Fung, Tak; Rheindt, Frank E

    2016-06-01

    How many species have gone extinct in modern times before being described by science? To answer this question, and thereby get a full assessment of humanity's impact on biodiversity, statistical methods that quantify undetected extinctions are required. Such methods have been developed recently, but they are limited by their reliance on parametric assumptions; specifically, they assume the pools of extant and undetected species decay exponentially, whereas real detection rates vary temporally with survey effort and real extinction rates vary with the waxing and waning of threatening processes. We devised a new, nonparametric method for estimating undetected extinctions. As inputs, the method requires only the first and last date at which each species in an ensemble was recorded. As outputs, the method provides estimates of the proportion of species that have gone extinct, detected, or undetected and, in the special case where the number of undetected extant species in the present day is assumed close to zero, of the absolute number of undetected extinct species. The main assumption of the method is that the per-species extinction rate is independent of whether a species has been detected or not. We applied the method to the resident native bird fauna of Singapore. Of 195 recorded species, 58 (29.7%) have gone extinct in the last 200 years. Our method projected that an additional 9.6 species (95% CI 3.4, 19.8) have gone extinct without first being recorded, implying a true extinction rate of 33.0% (95% CI 31.0%, 36.2%). We provide R code for implementing our method. Because our method does not depend on strong assumptions, we expect it to be broadly useful for quantifying undetected extinctions. © 2016 Society for Conservation Biology.

  15. Undetected common mental disorders in long-term sickness absence

    DEFF Research Database (Denmark)

    Søgaard, Hans Jørgen

    2012-01-01

    Background. Undetected Common Mental Disorders (CMDs) amongst people on sick leave complicate rehabilitation and return to work because appropriate treatments are not initiated. Aims. The aim of this study is to estimate (1) the frequencies of CMD, (2) the predictors of undetected CMD, and (3...... individuals registered on LSA who were sick-listed without a psychiatric sick leave diagnosis. In this respect, Phase 1 included 831 individuals, who were screened for mental disorders. In Phase 2, following the screening of Phase 1, 227 individuals were thoroughly examined by a psychiatrist applying Present...... State Examination. The analyses of the study were carried out based on the 227 individuals from Phase 2 and, subsequently, weighted to be representative of the 831 individuals in Phase 1. Results. The frequencies of undetected mental disorders among all sick-listed individuals were for any psychiatric...

  16. CTC Sentinel. Volume 6, Issue 8, August 2013

    Science.gov (United States)

    2013-08-01

    future. Syria,” CTC Sentinel 6:8 (2013). 16 For some interesting work on this issue, see Thomas Hegghammer, “Should I Stay or Should I Go? Explain- ing...the late 1980s and early 1 Arie Perliger, “Democracy in an Ongoing Conflict: The Politics of Defence in Israel,” in James Forest and Isaiah Wilson...people of Syria and Iran…will not Hates Most, U.S. or Iran?” Bloomberg, February 5, 2013. 24 Thomas Erdbrink, “Khamenei: Iran Will Back ‘Any Nations

  17. Effects of undetected data quality issues on climatological analyses

    Directory of Open Access Journals (Sweden)

    S. Hunziker

    2018-01-01

    Full Text Available Systematic data quality issues may occur at various stages of the data generation process. They may affect large fractions of observational datasets and remain largely undetected with standard data quality control. This study investigates the effects of such undetected data quality issues on the results of climatological analyses. For this purpose, we quality controlled daily observations of manned weather stations from the Central Andean area with a standard and an enhanced approach. The climate variables analysed are minimum and maximum temperature and precipitation. About 40 % of the observations are inappropriate for the calculation of monthly temperature means and precipitation sums due to data quality issues. These quality problems undetected with the standard quality control approach strongly affect climatological analyses, since they reduce the correlation coefficients of station pairs, deteriorate the performance of data homogenization methods, increase the spread of individual station trends, and significantly bias regional temperature trends. Our findings indicate that undetected data quality issues are included in important and frequently used observational datasets and hence may affect a high number of climatological studies. It is of utmost importance to apply comprehensive and adequate data quality control approaches on manned weather station records in order to avoid biased results and large uncertainties.

  18. Towards the Biological Understanding of CTC: Capture Technologies, Definitions and Potential to Create Metastasis

    Directory of Open Access Journals (Sweden)

    Ana M.C. Barradas

    2013-12-01

    Full Text Available Circulating Tumor Cells (CTC are rare cells originated from tumors that travel into the blood stream, extravasate to different organs of which only a small fraction will develop into metastasis. The presence of CTC enumerated with the CellSearch system is associated with a relative short survival and their continued presence after the first cycles of therapy indicates a futile therapy in patients with metastatic carcinomas. Detailed characterization of CTC holds the promise to enable the choice of the optimal therapy for the individual patients during the course of the disease. The phenotype, physical and biological properties are however not well understood making it difficult to assess the merit of recent technological advancements to improve upon the capture of CTC or to evaluate their metastatic potential. Here we will discuss the recent advances in the classification of CTC captured by the CellSearch system, the implications of their features and numbers. Latest capture platforms are reviewed and placed in the light of technology improvements needed to detect CTC. Physical properties, phenotype, viability and proliferative potential and means to assess their proliferation and metastatic capacity will be summarized and placed in the context of the latest CTC capture platforms.

  19. CTC1-STN1 coordinates G- and C-strand synthesis to regulate telomere length.

    Science.gov (United States)

    Gu, Peili; Jia, Shuting; Takasugi, Taylor; Smith, Eric; Nandakumar, Jayakrishnan; Hendrickson, Eric; Chang, Sandy

    2018-05-17

    Coats plus (CP) is a rare autosomal recessive disorder caused by mutations in CTC1, a component of the CST (CTC1, STN1, and TEN1) complex important for telomere length maintenance. The molecular basis of how CP mutations impact upon telomere length remains unclear. The CP CTC1 L1142H mutation has been previously shown to disrupt telomere maintenance. In this study, we used CRISPR/Cas9 to engineer this mutation into both alleles of HCT116 and RPE cells to demonstrate that CTC1:STN1 interaction is required to repress telomerase activity. CTC1 L1142H interacts poorly with STN1, leading to telomerase-mediated telomere elongation. Impaired interaction between CTC1 L1142H :STN1 and DNA Pol-α results in increased telomerase recruitment to telomeres and further telomere elongation, revealing that C:S binding to DNA Pol-α is required to fully repress telomerase activity. CP CTC1 mutants that fail to interact with DNA Pol-α resulted in loss of C-strand maintenance and catastrophic telomere shortening. Our findings place the CST complex as an important regulator of both G-strand extensions by telomerase and C-strand synthesis by DNA Pol-α. © 2018 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd.

  20. Undetectable inhibin B serum levels in men after testicular irradiation

    DEFF Research Database (Denmark)

    Petersen, P M; Andersson, A M; Rørth, M

    1999-01-01

    A group of men treated with testicular irradiation for carcinoma in situ in the remaining testis after orchidectomy for unilateral testicular germ cell cancer was used as a model to study of the effect of selective eradication of germ cells on the levels of serum inhibin B in the human male....... Thirteen men with verified spermatogenesis and detectable preirradiation levels of serum inhibin B (median, 55; range, 23-193 pg/mL) were investigated before and after testicular irradiation (14-20 Gy). All patients had undetectable levels of inhibin B 2-12 months (median, 5 months) after radiotherapy (...

  1. CTC Sentinel. Volume 9, Issue 4. April 2016

    Science.gov (United States)

    2016-09-21

    stakes are high. Since the Islamic State, unlike al-Qa`ida and its various regional affiliates, places such great em - phasis on its image as state...not going to bomb all the banks in Mosul or starve the economy of millions of people. There are material constraints to what we can do while ISIS...close to the investigation told CNN that the laptop bomb was sophisticated and went undetected by an airport X-ray machine.c In a statement released on

  2. Indication of prenatal diagnosis in pregnancies complicated by undetectable second-trimester maternal serum estriol levels.

    Science.gov (United States)

    Minsart, Anne-Frédérique; Van Onderbergen, Anne; Jacques, Francotte; Kurt, Crener; Gillerot, Yves

    2008-07-01

    Undetectable maternal serum unconjugated estriol levels in the second-trimester screening test have been associated with congenital pathology and an adverse pregnancy outcome. We reviewed outcomes of pregnancies with undetectable levels of estriol (threatened fetal abortion, one case of multiple congenital anomalies and one case of isolated adrenocorticotropin hormone deficiency. There were 6 women remaining with unexplained undetectable estriol. Undetectable maternal estriol values may indicate a severe fetal pathology and should lead to further investigations.

  3. Superconductivity in the W-Tc and W2C-Tc systems

    International Nuclear Information System (INIS)

    Giorgi, A.L.

    1985-01-01

    A series of compositions in the W-Tc, W 2 C-Re and W 2 C-Tc systems were prepared and examined for superconductivity. The crystal structure, lattice parameters and superconducting transition temperatures of the W 2 C-Tc are reported for the first time. Similar measurements were made on the W-Tc and W 2 C-Re systems and the results compared with previous published results for these systems. 7 refs., 2 figs., 2 tabs

  4. Computed tomographic colonography (CTC) performance: one-year clinical follow-up

    International Nuclear Information System (INIS)

    Duff, S.E.; Murray, D.; Rate, A.J.; Richards, D.M.; Kumar, N.A. Mahesh

    2006-01-01

    Aim: Computed tomographic colonography (CTC) represents a valuable advance in imaging technology for patients with colonic symptoms who are unfit for or fail to complete investigation with conventional techniques of colonoscopy or barium enema. The aim of this study was to examine whether CTC was sufficient to exclude colorectal cancer in such a population. As our patients were unfit for or unable to complete conventional investigations, we used 1 year clinical follow-up to exclude colonic malignancy. Materials and Methods: CTC examination was performed using multi-slice CT in patients fitting pre-determined criteria. All patients who had completed 12 months of follow-up after CTC were included. Data were extracted from patient records and lack of presentation within the 12 months following a negative CTC was assumed to equate to lack of colorectal cancer at initial investigation. Results: One hundred and twelve patients underwent CTC with a median age of 78 years (range 39-95) and median follow-up of 18 months (range 12-26). CTC detected 7 colorectal cancers, with 3 false positives and 1 false negative, giving a sensitivity of 87.5% and specificity of 97.1% for the detection of colorectal cancer. Conclusions: CTC is a good imaging tool for the exclusion of colorectal cancer in a population unfit for or unable to complete colonoscopy or barium enema, with reasonable sensitivity and specificity for detection of colorectal cancer. However, the optimum investigative strategy for fitter symptomatic individuals is still debated and should be clarified by the results of ongoing randomised controlled trials

  5. T cells recognizing a peptide contaminant undetectable by mass spectrometry

    DEFF Research Database (Denmark)

    Brezar, Vedran; Culina, Slobodan; Østerbye, Thomas

    2011-01-01

    Synthetic peptides are widely used in immunological research as epitopes to stimulate their cognate T cells. These preparations are never completely pure, but trace contaminants are commonly revealed by mass spectrometry quality controls. In an effort to characterize novel major histocompatibility...... complex (MHC) Class I-restricted ß-cell epitopes in non-obese diabetic (NOD) mice, we identified islet-infiltrating CD8+ T cells recognizing a contaminating peptide. The amount of this contaminant was so small to be undetectable by direct mass spectrometry. Only after concentration by liquid...... chromatography, we observed a mass peak corresponding to an immunodominant islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP)(206-214) epitope described in the literature. Generation of CD8+ T-cell clones recognizing IGRP(206-214) using a novel method confirmed the identity...

  6. Quantum optical measurements with undetected photons through vacuum field indistinguishability.

    Science.gov (United States)

    Lee, Sun Kyung; Yoon, Tai Hyun; Cho, Minhaeng

    2017-07-26

    Quantum spectroscopy and imaging with undetected idler photons have been demonstrated by measuring one-photon interference between the corresponding entangled signal fields from two spontaneous parametric down conversion (SPDC) crystals. In this Report, we present a new quantum optical measurement scheme utilizing three SPDC crystals in a cascading arrangement; here, neither the detection of the idler photons which interact with materials of interest nor their conjugate signal photons which do not interact with the sample is required. The coherence of signal beams in a single photon W-type path-entangled state is induced and modulated by indistinguishabilities of the idler beams and crucially the quantum vacuum fields. As a result, the optical properties of materials or objects interacting with the idler beam from the first SPDC crystal can be measured by detecting second-order interference between the signal beams generated by the other two SPDC crystals further down the set-up. This gedankenexperiment illustrates the fundamental importance of vacuum fields in generating an optical tripartite entangled state and thus its crucial role in quantum optical measurements.

  7. Teenage motherhood: its relationship to undetected learning problems.

    Science.gov (United States)

    Rauch-Elnekave, H

    1994-01-01

    This study describes characteristics of a group of 64 adolescent mothers and their infants who participated in a program for teenage mothers run by a local health department. A majority of the girls for whom California Achievement Test (CAT) scores were available scored one or more years below grade level in reading and in language skills. Relative delays in infant development (language and social domains) were also documented. High levels of self-esteem as well as general social acceptance (by adults and peers) of early out-of-wedlock parenting suggest that early motherhood may represent an alternative avenue to experiencing success for girls who are having academic difficulties. These findings, which suggest the likelihood of a high incidence of undetected learning problems in this population, indicate that these difficulties may have a significant relationship to the high rate of school dropout associated with adolescent motherhood. The findings bring into question the notion of "unintended pregnancies" and the wisdom of current federal policies for preventing adolescent parenthood that rely on the promotion of abstinence.

  8. Idiopathic Acquired Hemophilia A with Undetectable Factor VIII Inhibitor

    Directory of Open Access Journals (Sweden)

    Nicholas B. Abt

    2014-01-01

    Full Text Available Objective. We present the case of a 73-year-old female, with no family or personal history of a bleeding disorder, who had a classic presentation for acquired hemophilia A. Factor VIII activity was low but detectable and a factor VIII inhibitor was undetectable. Methods. The patient’s plasma was comprehensively studied to determine the cause of the acquired coagulopathy. Using the Nijmegen modification of the Bethesda assay, no factor VIII autoantibody was measureable despite varying the incubation time from 1 to 3 hours. Results. The aPTT was prolonged at 46.8 seconds, which did not correct in the 4 : 1 mix but did with 1 : 1 mix. Using a one stage factor VIII activity assay, the FVIII activity was 16% and chromogenic FVIII activity was also 16%. The patient was treated with recombinant FVII and transfusion, significantly reducing bleeding. Long-term therapy was initiated with cyclophosphamide and prednisone with normalization of FVIII activity. Conclusions. Physicians can be presented with the challenging clinical picture of an acquired factor VIII inhibitor without a detectable inhibitor by the Bethesda assay. Standard therapy for an acquired hemophilia A should be considered.

  9. Determination analaysis of the power losses of transformers with continuously transpored conductors (CTC) based fuzzy logic

    Science.gov (United States)

    Kaloko, Bambang Sri; Atsari, Erinna Dyah

    2017-03-01

    Electric motive force which flows into the iron core continuously on a plate - plate iron isolated may cause heat posed by current eddy (eddy current). No water loss occurs due to detainees on the circuit at the the flow of current load because this loss happened on the entanglement of the transformer is made of copper. Continuously Transposed Conductors (CTC) consist of a number of enameled rectangular wires (5-84 strands) made into an assembly. Each strand is transposed in turn to each position in the cable and is then covered with layers of insulation paper. Continuously Transposed Conductors are used in winding wires for medium and ultra high power transformers. CTC is manufactured by OFHC copper and indeed, is able to supply polyester roped. CTC which has been designed to reduce production cost, oil pocket and improve cooling efficiency. Hardened type CTC (CPR1, CPR2, and CPR3: BS1432) and Self-bonding CTC which can be used to improve mechanical and electrical strength are also available. This analysis is performed using the methods of fuzzy logic in taking account of the resources.

  10. Extracolonic findings (ECF) on CT colonography (CTC) in patients presenting with colorectal symptoms

    Energy Technology Data Exchange (ETDEWEB)

    Sarit Badiani, Sarit; Karandikar, Sharad [Dept. of General Surgery, Heart of England Foundation Trust, Birmingham (United Kingdom); Tomas-Hernandez, Silvia; Roy-Choudhury; Shuvro [Dept. of Radiology, Heart of England Foundation Trust, Birmingham (United Kingdom)], e-mail: shurvrorc@googlemail.com

    2013-10-15

    Background: Computed tomographic colonography (CTC) is now an established method for imaging the colon and rectum in the screening and symptomatic setting. Additional benefit of CTC is the ability to assess for extracolonic findings especially in patients presenting with colorectal symptoms. Purpose: To determine prevalence of extracolonic findings (ECF) in symptomatic patients undergoing CTC and determine accuracy of CTC for exclusion of significant abdominal disease and extracolonic malignancy (ECM). Material and Methods: A total of 1359 unenhanced prone and postcontrast supine CTC studies were performed between March 2002 and December 2007. ECF were retrospectively classified according to C-RADS criteria into E1 to E4 findings. For ECM, a gold standard of clinical and/or radiological follow-up supplemented with data from the regional cancer registry with a median follow-up of 42 months was created. Sensitivity and negative predictive values for ECM was calculated. Results: Following exclusions, 1177 CTCs were analyzed. Of 1423 extracolonic findings reported, 328/1423 (23%) E3 and 100/1423 (7%) E4 (including six eventual FP studies) findings were identified. Thirty-two ECMs were confirmed following further investigations. Seven further small ECMs were detected during the entire follow-up, of which two were potentially visible in retrospect (false-negative studies). Additional tests were generated from 55/1177 (4.7%) studies. Sensitivity and negative predictive value for ECM was 94.1% (95% CI 78.9 - 98.9%) and 99.8% (95% CI 99.3 - 99.9%), respectively. Conclusion: One in 37 patients were found to have an ECM. Two potentially detectable cancers were missed. Only a small proportion of patients underwent additional work-up.

  11. Extracolonic findings (ECF) on CT colonography (CTC) in patients presenting with colorectal symptoms.

    Science.gov (United States)

    Badiani, Sarit; Tomas-Hernandez, Silvia; Karandikar, Sharad; Roy-Choudhury, Shuvro

    2013-10-01

    Computed tomographic colonography (CTC) is now an established method for imaging the colon and rectum in the screening and symptomatic setting. Additional benefit of CTC is the ability to assess for extracolonic findings especially in patients presenting with colorectal symptoms. To determine prevalence of extracolonic findings (ECF) in symptomatic patients undergoing CTC and determine accuracy of CTC for exclusion of significant abdominal disease and extracolonic malignancy (ECM). A total of 1359 unenhanced prone and postcontrast supine CTC studies were performed between March 2002 and December 2007. ECF were retrospectively classified according to C-RADS criteria into E1 to E4 findings. For ECM, a gold standard of clinical and/or radiological follow-up supplemented with data from the regional cancer registry with a median follow-up of 42 months was created. Sensitivity and negative predictive values for ECM was calculated. Following exclusions, 1177 CTCs were analyzed. Of 1423 extracolonic findings reported, 328/1423 (23%) E3 and 100/1423 (7%) E4 (including six eventual FP studies) findings were identified. Thirty-two ECMs were confirmed following further investigations. Seven further small ECMs were detected during the entire follow-up, of which two were potentially visible in retrospect (false-negative studies). Additional tests were generated from 55/1177 (4.7%) studies. Sensitivity and negative predictive value for ECM was 94.1% (95% CI 78.9-98.9%) and 99.8% (95% CI 99.3-99.9%), respectively. One in 37 patients were found to have an ECM. Two potentially detectable cancers were missed. Only a small proportion of patients underwent additional work-up.

  12. Clearance Analysis of CTC2 (on ELC4) to S-TRRJ HRS Radiator Rotation Envelope

    Science.gov (United States)

    Liddle, Donn

    2014-01-01

    In response to the planned retirement of the Space Shuttle Program, International Space Station (ISS) management began stockpiling spare parts on the ISS. Many of the larger orbital replacement units were stored on the Expedite the Processing of Experiments to Space Station (EXPRESS) Logistics Carriers (ELCs) mounted on the end of the S3 and P3 truss segments, immediately outboard of the Thermal Radiator Rotary Joints (TRRJs) and their attached radiators. In an August 2009 computer-aided design (CAD) assessment, it was determined that mounting the Cargo Transport Container (CTC) 2 on the inboard face of ELC4 as planned would create insufficient clearance between the CTC2 and the rotational envelope of the radiators when the TRRJs were rotated to a gamma angle of 35.0 degrees. The true clearance would depend on how the Unpressurized Cargo Carrier Attachment System (UCCAS) was mounted to the S3 truss and how the ELC4 was attached to it. If the plane of the UCCAS attachment points were tilted even slightly inboard, it would significantly change the clearance between CTC2 and the Starboard TRRJ (S-TRRJ) radiators. Additionally, since CTC2 would be covered in multilayer insulation (MLI), the true outer profile of CTC2 was not captured in the CAD models used for the clearance assessment. It was possible that, even if the S-TRRJ radiators cleared CTC2, they could snag the MLI covering. In the fall of 2010, the Image Science and Analysis Group (ISAG) was asked to perform an on-orbit clearance analysis to determine the location of CTC2 on ELC4 and the S-TRRJ radiators at the angle of closest approach so that a positive clearance could be assured. To provide the measurements as quickly as possible to aid in the assessment, it was decided that the clearance analysis would be broken into two phases. Phase I: The location and orientation of the UCCAS fittings, which support and hold the ELC4 in place, would be measured relative to the ISS Analytical Coordinate System (ISSACS

  13. [Identification of Circulating Tumor Cell(CTC)in Breast Cancer Patients Using a Newly Established CTC Detecting System].

    Science.gov (United States)

    Nagata, Takuya; Ohnaga, Takashi; Lu, Xiao Long; Watanabe, Toru; Hirano, Katsuhisa; Okumura, Tomoyuki; Tsukada, Kazuhiro

    2015-10-01

    We developed a new circulating tumor cell (CTC) chip in order to identify CTCs in the peripheral blood of cancer patients. In this study, we aimed to identify CTCs in the blood of breast cancer patients by using this CTC detecting system. In addition, we used this system to evaluate the response to anticancer agents. We were able to identify CTCs in 5 of 6 patients. In addition, the system showed that the number of CTCs had decreased after chemotherapy. Thus, the CTC detecting system was useful in the identification of CTCs in the breast cancer patients and in the early prediction of response to anticancer agents.

  14. A case of moderate liver enzyme elevation after acute acetaminophen overdose despite undetectable acetaminophen level and normal initial liver enzymes.

    Science.gov (United States)

    Bebarta, Vikhyat S; Shiner, Drew C; Varney, Shawn M

    2014-01-01

    Liver function test (LFT) increase is an early sign of acetaminophen (APAP) toxicity. Typically, when an acute overdose patient is evaluated and has an initial undetectable APAP level and normal liver enzymes, the patient is not treated with N-acetylcysteine, and liver enzymes are not expected to increase later. We report a case of moderate LFT increase despite normal LFTs and an undetectable APAP level after delayed presentation of an APAP ingestion. A 22-year-old male with no medical history ingested 15-25 hydrocodone/APAP tablets (5 mg/500 mg). His suicide note and his bunkmate corroborated the overdose time. He arrived at the emergency department 16 hours after ingestion. At that time, his APAP level was enzymes were normal [aspartate transaminase (AST) 31 U/L and alanine transaminase (ALT) 34 U/L]. Twenty-nine hours after ingestion, the psychiatry team obtained LFTs (AST 45, ALT 61). He had persistent nausea and diffuse abdominal pain. On repeat analysis, the APAP level at 36 hours was found to be <10 μg/mL, AST 150, and ALT 204. After 2 more days of increasing LFTs and persistent abdominal pain and nausea, the toxicology department was consulted, the patient was transferred to the medicine department, and intravenous N-acetylcysteine was started 66 hours after ingestion. He was treated for 16 hours and had a significant decline in LFTs and symptom resolution. His prothrombin time, bilirubin, lactate, creatinine, and mental status were normal throughout the admission. Other cases of LFT increase were excluded. Our case report illustrates that a moderate increase in liver transaminase may occur despite an initial undetectable APAP level and normal transaminases after a delayed presentation. In our case, no serious clinical effects were reported.

  15. Undetected Toxicity Risk in Pharmacogenetic Testing for Dihydropyrimidine Dehydrogenase

    Directory of Open Access Journals (Sweden)

    Felicia Stefania Falvella

    2015-04-01

    Full Text Available Fluoropyrimidines, the mainstay agents for the treatment of colorectal cancer, alone or as a part of combination therapies, cause severe adverse reactions in about 10%–30% of patients. Dihydropyrimidine dehydrogenase (DPD, a key enzyme in the catabolism of 5-fluorouracil, has been intensively investigated in relation to fluoropyrimidine toxicity, and several DPD gene (DPYD polymorphisms are associated with decreased enzyme activity and increased risk of fluoropyrimidine-related toxicity. In patients carrying non-functional DPYD variants (c.1905+1G>A, c.1679T>G, c.2846A>T, fluoropyrimidines should be avoided or reduced according to the patients’ homozygous or heterozygous status, respectively. For other common DPYD variants (c.496A>G, c.1129-5923C>G, c.1896T>C, conflicting data are reported and their use in clinical practice still needs to be validated. The high frequency of DPYD polymorphism and the lack of large prospective trials may explain differences in studies’ results. The epigenetic regulation of DPD expression has been recently investigated to explain the variable activity of the enzyme. DPYD promoter methylation and its regulation by microRNAs may affect the toxicity risk of fluoropyrimidines. The studies we reviewed indicate that pharmacogenetic testing is promising to direct personalised dosing of fluoropyrimidines, although further investigations are needed to establish the role of DPD in severe toxicity in patients treated for colorectal cancer.

  16. Relationship between irreversible alopecia and exposure to cyclophosphamide, thiotepa and carboplatin (CTC) in high-dose chemotherapy

    NARCIS (Netherlands)

    de Jonge, M. E.; Mathôt, R. A. A.; Dalesio, O.; Huitema, A. D. R.; Rodenhuis, S.; Beijnen, J. H.

    2002-01-01

    Reversible alopecia is a commonly observed, important and distressing complication of chemotherapy. Permanent alopecia, however, is rare after standard-dose therapy, but has occasionally been observed after high-dose chemotherapy with cyclophosphamide, thiotepa and carboplatin (CTC). We evaluated

  17. The extension of the range of application of the CTC-800 climate chamber

    OpenAIRE

    DOLGIKH ARTEM; ALEXANDROVA NATALIA; POPOVA IRINA

    2017-01-01

    The article presents a research work aimed at potential improvement of the climate chamber CTC-800 to simplify the proof test of it and automate the processes it performs. To this end, the authors justify the need to apply the meter and controller of temperature and humidity of the MPR51 type as well as consider the functional MPR51-SHCH 4, its link with computer, and the compatibility of its operation with the climate chamber.

  18. Cerebroretinal microangiopathy with calcifications and cysts associated with CTC1 and NDP mutations.

    Science.gov (United States)

    Romaniello, Romina; Arrigoni, Filippo; Citterio, Andrea; Tonelli, Alessandra; Sforzini, Cinzia; Rizzari, Carmelo; Pessina, Marco; Triulzi, Fabio; Bassi, Maria Teresa; Borgatti, Renato

    2013-12-01

    Mutations in the conserved telomere maintenance component 1 (CTC1) gene were recently described in Coats plus syndrome and in cerebroretinal microangiopathy with calcifications and cysts. Norrie disease protein (NDP) gene was found mutated in Norrie disease, in Familial Exudative Vitreoretinopathy, and in Coats syndrome. Here we describe a boy affected by Norrie disease who developed typical features of cerebroretinal microangiopathy with calcifications and cysts. Direct sequencing of the CTC1 and NDP genes in this patient shows the presence of compound heterozygosity for 2 mutations in CTC1 (c.775G>A, pV259M and a novel microdeletion c.1213delG) and a missense mutation in the NDP gene (c.182T>C, p.L61P). Based on these genetic findings and on the expression of both genes in endothelial cells, we postulate that microangiopathy might be a primary underlying pathologic abnormality in cerebroretinal microangiopathy with calcifications and cysts. This hypothesis is further supported by magnetic resonance imaging (MRI) data showing multiple minute calcifications in the deep gray nuclei and in terminal arteriolar zones.

  19. Predictors of undetectable plasma viral load in HIV-positive adults receiving antiretroviral therapy in Southern Brazil

    Directory of Open Access Journals (Sweden)

    Marysabel Pinto Telis Silveira

    Full Text Available Factors associated with undetectable viral load ( or = 95% of adherence (CI 95% 1,80-13,28; CI 95% 1,73-9,53, compared with less than 60% adherence; it was greater for less than 6 months in treatment (OR = 3.37; CI 95% 1.09-10.46; and smaller for viral load previous to adherence measurement > or = 5.2 log10 (OR = 0.19; CI95% 0.06-0.58, adjusted for these variables and sex, age, clinical status, current immune status, group of drugs and interval between the two measurements of viral load. The crude odds were lower for age 16-24 years and use of Nucleoside Analog Reverse Transcriptase Inhibitors only, but these effects were not significant in the multivariate model. There was no evidence of effect of sex, clinical status, current immune status, and changes in treatment regimen. Treatment adherence gave the largest effect. Motivational interventions directed at adherence may improve treatment effectiveness.

  20. Becoming "Undetectable": Longitudinal Narratives of Gay Men's Sex Lives After a Recent HIV Diagnosis.

    Science.gov (United States)

    Grace, Daniel; Chown, Sarah A; Kwag, Michael; Steinberg, Malcolm; Lim, Elgin; Gilbert, Mark

    2015-08-01

    We explore gay men's sex life narratives following their diagnosis with an acute or recent HIV infection. All participants received an acute (n = 13) or recent (n = 12) HIV diagnosis and completed a series of self-administered questionnaires and in-depth qualitative interviews over a one-year period or longer. Over the course of four qualitative interviews, participants frequently spoke of the role of medications (e.g., decisions to start treatment) and changing viral loads (e.g., discourses of becoming "undetectable") in relation to their sex lives since being diagnosed with HIV. Many men talked about milestones relating to initiating medication and viral load as informing their shifting sexual behaviors and identities as HIV-positive--or "undetectable"--gay men. The narratives of our participants provide insight regarding complex negotiations and processes of decision-making over time related to sex, counseling needs, treatment initiation, viral load, and the significance of undetectability as an emergent identity.

  1. Combining heterogeneous features for colonic polyp detection in CTC based on semi-definite programming

    Science.gov (United States)

    Wang, Shijun; Yao, Jianhua; Petrick, Nicholas A.; Summers, Ronald M.

    2009-02-01

    Colon cancer is the second leading cause of cancer-related deaths in the United States. Computed tomographic colonography (CTC) combined with a computer aided detection system provides a feasible combination for improving colonic polyps detection and increasing the use of CTC for colon cancer screening. To distinguish true polyps from false positives, various features extracted from polyp candidates have been proposed. Most of these features try to capture the shape information of polyp candidates or neighborhood knowledge about the surrounding structures (fold, colon wall, etc.). In this paper, we propose a new set of shape descriptors for polyp candidates based on statistical curvature information. These features, called histogram of curvature features, are rotation, translation and scale invariant and can be treated as complementing our existing feature set. Then in order to make full use of the traditional features (defined as group A) and the new features (group B) which are highly heterogeneous, we employed a multiple kernel learning method based on semi-definite programming to identify an optimized classification kernel based on the combined set of features. We did leave-one-patient-out test on a CTC dataset which contained scans from 50 patients (with 90 6-9mm polyp detections). Experimental results show that a support vector machine (SVM) based on the combined feature set and the semi-definite optimization kernel achieved higher FROC performance compared to SVMs using the two groups of features separately. At a false positive per patient rate of 7, the sensitivity on 6-9mm polyps using the combined features improved from 0.78 (Group A) and 0.73 (Group B) to 0.82 (p<=0.01).

  2. Undetected error probability for data services in a terrestrial DAB single frequency network

    NARCIS (Netherlands)

    Schiphorst, Roelof; Hoeksema, F.W.; Slump, Cornelis H.; Veldhuis, Raymond N.J.; Veldhuis, R.N.J.; Cronie, H.S.

    2007-01-01

    DAB (Digital Audio Broadcasting) is the European successor of FM radio. Besides audio services, other services such as traffic information can be provided. An important parameter for data services is the probability of non-recognized or undetected errors in the system. To derive this probability, we

  3. Is the cervical spine clear? Undetected cervical fractures diagnosed only at autopsy.

    Science.gov (United States)

    Sweeney, J F; Rosemurgy, A S; Gill, S; Albrink, M H

    1992-10-01

    Undetected cervical-spine injuries are a nemesis to both trauma surgeons and emergency physicians. Radiographic protocols have been developed to avoid missing cervical-spine fractures but are not fail-safe. Three case reports of occult cervical fractures documented at autopsy in the face of normal cervical-spine radiographs and computerized tomography scans are presented.

  4. Prevalence and distribution of colonic diverticula assessed with CT colonography (CTC)

    Energy Technology Data Exchange (ETDEWEB)

    De Cecco, Carlo Nicola [University of Rome ' ' Sapienza' ' - Polo Pontino, Department of Radiological Sciences, Oncology and Pathology, Latina (Italy); Medical University of South Carolina, Department of Radiology and Radiological Sciences, Charleston, SC (United States); Ciolina, Maria; Rengo, Marco; Bellini, Davide; Muscogiuri, Giuseppe; Iafrate, Franco; Laghi, Andrea [University of Rome ' ' Sapienza' ' - Polo Pontino, Department of Radiological Sciences, Oncology and Pathology, Latina (Italy); Annibale, Bruno [University of Rome ' ' Sapienza' ' - Sant' Andrea Hospital, Department of Digestive and Liver Disease, Rome (Italy); Maruotti, Antonello [University ' ' Roma Tre' ' , Department of Public Institutions, Economy and Society, Rome (Italy); University of Southampton, Southampton Statistical Sciences Research Institute and School of Mathematics, Southampton (United Kingdom); Saba, Luca [Azienda Ospedaliera Universitaria di Cagliari, Department of Radiology, Cagliari (Italy)

    2016-03-15

    This study aimed to evaluate the prevalence of colonic diverticula according to age, gender, distribution, disease extension and symptoms with CT colonography (CTC). The study population included 1091 consecutive patients who underwent CTC. Patients with diverticula were retrospectively stratified according to age, gender, clinical symptoms and colonic segment involvement. Extension of colonic diverticula was evaluated using a three-point quantitative scale. Using this data, a multivariate regression analysis was applied to investigate the existence of any correlation among variables. Colonic diverticula were observed in 561 patients (240 men, mean age 68 ± 12 years). Symptomatic uncomplicated diverticular disease (SUDD) was present in 47.4 % of cases. In 25.6 % of patients ≤40 years, at least one diverticulum in the colon was observed. Prevalence of right-sided diverticula in patients >60 years was 14.2 % in caecum and 18.5 % in ascending colon. No significant difference was found between symptomatic and asymptomatic patients regarding diverticula prevalence and extension. No correlation was present between diverticula extension and symptoms. The incidence of colonic diverticula appears to be greater than expected. Right colon diverticula do not appear to be an uncommon finding, with their prevalence increasing with patient age. SUDD does not seem to be related to diverticula distribution and extension. (orig.)

  5. Prevalence and distribution of colonic diverticula assessed with CT colonography (CTC)

    International Nuclear Information System (INIS)

    De Cecco, Carlo Nicola; Ciolina, Maria; Rengo, Marco; Bellini, Davide; Muscogiuri, Giuseppe; Iafrate, Franco; Laghi, Andrea; Annibale, Bruno; Maruotti, Antonello; Saba, Luca

    2016-01-01

    This study aimed to evaluate the prevalence of colonic diverticula according to age, gender, distribution, disease extension and symptoms with CT colonography (CTC). The study population included 1091 consecutive patients who underwent CTC. Patients with diverticula were retrospectively stratified according to age, gender, clinical symptoms and colonic segment involvement. Extension of colonic diverticula was evaluated using a three-point quantitative scale. Using this data, a multivariate regression analysis was applied to investigate the existence of any correlation among variables. Colonic diverticula were observed in 561 patients (240 men, mean age 68 ± 12 years). Symptomatic uncomplicated diverticular disease (SUDD) was present in 47.4 % of cases. In 25.6 % of patients ≤40 years, at least one diverticulum in the colon was observed. Prevalence of right-sided diverticula in patients >60 years was 14.2 % in caecum and 18.5 % in ascending colon. No significant difference was found between symptomatic and asymptomatic patients regarding diverticula prevalence and extension. No correlation was present between diverticula extension and symptoms. The incidence of colonic diverticula appears to be greater than expected. Right colon diverticula do not appear to be an uncommon finding, with their prevalence increasing with patient age. SUDD does not seem to be related to diverticula distribution and extension. (orig.)

  6. The Prognostic Role of Circulating Tumor Cells (CTC) in High-risk Non-muscle-invasive Bladder Cancer.

    Science.gov (United States)

    Busetto, Gian Maria; Ferro, Matteo; Del Giudice, Francesco; Antonini, Gabriele; Chung, Benjamin I; Sperduti, Isabella; Giannarelli, Diana; Lucarelli, Giuseppe; Borghesi, Marco; Musi, Gennaro; de Cobelli, Ottavio; De Berardinis, Ettore

    2017-08-01

    The purpose of this study was to evaluate the impact of circulating tumor cells (CTCs) as a prognostic marker in patients with high-risk non-muscle-invasive bladder cancer (NMIBC) and assess the efficacy and reliability of 2 different CTC isolation methods. Globally, 155 patients with a pathologically confirmed diagnosis of high-risk NMIBC were included (pT1G3 with or without carcinoma in situ) and underwent transurethral resection of bladder tumor (TURB) after a blood withdrawal for CTC evaluation. A total of 101 patients (Group A) had their samples analyzed with the CellSearch automated system, and 54 (Group B) had their samples analyzed with the CELLection Dynabeads manual system. Patients were followed for 28 months, and during this interval, there were a total of 65 (41.9%) recurrences, 27 (17.4%) disease progressions, and 9 (5.8%) lymph node and/or bone metastasis. In our CTC analysis, there were 20 (19.8%) positive patients in Group A and 24 in Group B (44.4%). In our analysis, we found a strong correlation between CTC presence and time to first recurrence; in Group A, we observed an incidence of recurrence in 75% of CTC-positive patients and in Group B of 83% of CTC-positive patients. The time to progression was also strongly correlated with CTCs: 65% and 29%, respectively, of those patients who progressed in those with CTCs in Group A and B. The study demonstrates the potential role of CTCs as a prognostic marker for risk stratification in patients with NMIBC, to predict both recurrence and progression. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. Undetectable hepatitis C virus RNA during syphilis infection in two HIV/HCV-co-infected patients

    DEFF Research Database (Denmark)

    Salado-Rasmussen, Kirsten; Knudsen, Andreas; Krarup, Henrik Bygum

    2014-01-01

    BACKGROUND: Treponema pallidum, the causative agent of syphilis, elicits a vigorous immune response in the infected host. This study sought to describe the impact of syphilis infection on hepatitis C virus (HCV) RNA levels in patients with HIV and chronic HCV infection. METHODS: Patients......-α), interferon gamma (IFN-γ), and IFN-γ-inducible protein 10 kDa (IP-10). RESULTS: Undetectable HCV RNA at the time of early latent syphilis infection was observed in 2 patients with HIV and chronic HCV infection. After treatment of the syphilis infection, HCV RNA levels increased again in patient 1, whereas...... patient 2 initiated HCV therapy and remained HCV RNA-negative. Available plasma samples obtained before and after the episode with undetectable HCV RNA were phylogenetically identical, making the possibility of spontaneous clearance and HCV reinfection less likely. The IL-10, TNF-α, and IP-10 levels...

  8. Probability of undetected error after decoding for a concatenated coding scheme

    Science.gov (United States)

    Costello, D. J., Jr.; Lin, S.

    1984-01-01

    A concatenated coding scheme for error control in data communications is analyzed. In this scheme, the inner code is used for both error correction and detection, however the outer code is used only for error detection. A retransmission is requested if the outer code detects the presence of errors after the inner code decoding. Probability of undetected error is derived and bounded. A particular example, proposed for NASA telecommand system is analyzed.

  9. Poor Government Oversight of Anham and Its Subcontracting Procedures Allowed Questionable Costs To Go Undetected

    Science.gov (United States)

    2011-07-30

    contractor purchasing system review of Anham. Management Comments and Audit Response The Defense Contract Mangement Agency and the U.S. Central... Introduction 1  Background 1  Government Agency Roles and Oversight Responsibilities 4  Objectives 7  Weak Government Oversight Resulted in Significant...Subcontracting Procedures Allowed Questionable Costs To Go Undetected SIGIR 11-022 July 30, 2011 Introduction Since 2003, the United States Government

  10. Modeling Bacteriocin Resistance and Inactivation of Listeria innocua LMG 13568 by Lactobacillus sakei CTC 494 under Sausage Fermentation Conditions

    Science.gov (United States)

    Leroy, Frédéric; Lievens, Kristoff; De Vuyst, Luc

    2005-01-01

    In mixed cultures, bacteriocin production by the sausage isolate Lactobacillus sakei CTC 494 rapidly inactivated sensitive Listeria innocua LMG 13568 cells, even at low bacteriocin activity levels. A small fraction of the listerial population was bacteriocin resistant. However, sausage fermentation conditions inhibited regrowth of resistant cells. PMID:16269805

  11. Tricistronic operon expression of the genes gcaD (tms), which encodes N-acetylglucosamine 1-phosphate uridyltransferase, prs, which encodes phosphoribosyl diphosphate synthetase, and ctc in vegetative cells of Bacillus subtilis

    DEFF Research Database (Denmark)

    Hilden, Ida; Krath, Britta N.; Hove-Jensen, Bjarne

    1995-01-01

    The gcaD, prs, and ctc genes were shown to be organized as a tricistronic operon. The transcription of the prs gene, measured as phosphoribosyl diphosphate synthetase activity, and of the ctc gene, measured as β-galactosidase activity specified by a ctc-lacZ protein fusion, were dependent...

  12. Functioning of the IPSN Crisis Technical Center (CTC) inside the Crisis National Organisation

    International Nuclear Information System (INIS)

    Cernes, A.

    1995-01-01

    A forethought about the organization and counter-actions to follow in case of reactor accident crisis has been carried out by the French nuclear partners (operators and public authorities). This forethought has led to the creation of a Crisis National Organization which determines the responsibilities and missions of each partner. Inside this organization, the IPSN (Institute for Nuclear Protection and Safety) plays the role of technical support and expert for the Safety Authority. To carry out these missions, a Crisis Technical Center has been installed for ten years in Fontenay-aux-Roses CEA center. This document is a presentation of the CTC activities and evolutions in the framework of the existing National Organization. The main axes along which this activity will evolve in the future are summarized. (J.S.). 3 figs

  13. Undetectable plasma viral load predicts normal survival in HIV-2-infected people in a West African village

    Directory of Open Access Journals (Sweden)

    Ricard Dominique

    2010-05-01

    Full Text Available Abstract Background There have been no previous studies of the long-term survival and temporal changes in plasma viral load among HIV-2 infected subjects. Methods 133 HIV-2 infected and 158 HIV-uninfected subjects from a rural area in North-west Guinea-Bissau, West Africa were enrolled into a prospective cohort study in 1991 and followed-up to mid-2009. Data were collected on four occasions during that period on HIV antibodies, CD4% and HIV-2 plasma viral load. Results Median age (interquartile range [IQR] of HIV-2 infected subjects at time of enrollment was 47 (36, 60 years, similar to that of HIV-uninfected control subjects, 49 (38, 62 (p = 0.4. Median (IQR plasma viral load and CD4 percentage were 347 (50, 4,300 copies/ml and 29 (22, 35 respectively. Overall loss to follow-up to assess vital status was small, at 6.7% and 6.3% for HIV-2 infected and uninfected subjects respectively. An additional 17 (12.8% and 16 (10.1% of HIV-2 infected and uninfected subjects respectively were censored during follow-up due to infection with HIV-1. The mortality rate per 100 person-years (95% CI was 4.5 (3.6, 5.8 among HIV-2 infected subjects compared to 2.1 (1.6, 2.9 among HIV-uninfected (age-sex adjusted rate ratio 1.9 (1.3, 2.8, p Viral load measurements were available for 98%, 78%, 77% and 61% HIV-2 infected subjects who were alive and had not become super-infected with HIV-1, in 1991, 1996, 2003 and 2006 respectively. Median plasma viral load (RNA copies per ml (IQR did not change significantly over time, being 150 (50, 1,554; n = 77 in 1996, 203 (50, 2,837; n = 47 in 2003 and 171 (50, 497; n = 31 in 2006. Thirty seven percent of HIV-2 subjects had undetectable viraemia ( Conclusions A substantial proportion of HIV-2 infected subjects in this cohort have stable plasma viral load, and those with an undetectable viral load (37% at study entry had a normal survival rate. However, the sequential laboratory findings need to be interpreted with caution given

  14. Positive correlation between postoperative tumor recurrence and changes in circulating tumor cell counts in pulmonary venous blood (pvCTC) during surgical manipulation in non-small cell lung cancer.

    Science.gov (United States)

    Hashimoto, Masaki; Tanaka, Fumihiro; Yoneda, Kazue; Takuwa, Teruhisa; Matsumoto, Seiji; Okumura, Yoshitomo; Kondo, Nobuyuki; Tsujimura, Tohru; Nakano, Takashi; Hasegawa, Seiki

    2018-01-01

    In non-small cell lung cancer (NSCLC), circulating tumor cells (CTC) are shed and circulate to the peripheral blood through the pulmonary vein. Previously, CTC count in pulmonary venous blood (pvCTC) was shown to significantly increase after surgical manipulation. Therefore, we assessed the correlation between the changes in the pvCTC count (ΔpvCTC) and clinical outcomes. Consecutive patients with peripheral-type, NSCLC, who underwent lobectomy or bi-lobectomy through open thoracotomy, were enrolled prospectively. Before and after lobectomy, 2.5 mL of blood was drawn from the associated lobar pulmonary vein (PV), and was served for the quantitative evaluation of CTC using the CellSearch ® system. The cut-off point of ΔpvCTC was determined according to clinical outcomes and ΔpvCTC using receiver operation characteristic (ROC) curve. Then the correlation between ΔpvCTC and clinical outcomes was evaluated by Kaplan-Meier analyses and log-rank test. In addition, the correlation between ΔpvCTC and perioperative variables was assessed. A total of 30 patients were enrolled, tumor recurrence occurred in 11 patients over a median follow-up of 64.4 months. Of these, 7 patients had distant metastasis and 4 had local recurrence. The median ΔpvCTC was 49 cells/2.5 mL, and pvCTC-count was increased during surgical manipulation in 24 patients (80%). We divided patients into two groups based on ΔpvCTC with the cut-off value as 119 cells/2.5 mL according to ROC curve. Significant shorter time to distant metastasis (TDM) (P=0.0123) was observed in high ΔpvCTC group (ΔpvCTC ≥119 cells/2.5 mL) than low ΔpvCTC group (ΔpvCTC <119 cells/ 2.5mL). Neither disease-free survival (DFS) nor overall survival (OS) was significantly correlated with ΔpvCTC. Increasing pvCTC count during surgical manipulation was significantly correlated with postoperative distant metastasis in completely resected NSCLC patients. Significant shorter TDM was observed in patient with high ΔpvCTC group.

  15. Clinically undetected retinal breaks causing retinal detachment: A review of options for management.

    Science.gov (United States)

    Gupta, Deepak; Ching, Jared; Tornambe, Paul E

    2017-08-12

    The successful detection of retinal breaks is a critical step in rhegmatogenous retinal detachment surgery in order to prevent persistent/recurrent retinal detachments. Not all retinal breaks causing retinal detachments are obvious. Retinal breaks may be obscured by opacities that are either anterior segment related, lens related, or posterior segment related. Rules to identify breaks based on subretinal fluid configuration are more difficult to apply in pseudophakic, aphakic, and scleral buckle encircled eyes-and in eyes with repeat detachments and those with proliferative vitreoretinopathy. Exudative detachments exhibit characteristic features and must be ruled out. A thorough clinical examination preoperatively is important even if a vitrectomy is planned. We review the incidence and causes of undetected breaks, along with preoperative/clinical issues that may hinder break detection. We review the literature with respect to investigative approaches and techniques that are available to the vitreoretinal surgeon when primary breaks remain clinically undetected during the preoperative examination. We broadly divide the surgical approaches into ones where the surgeon utilizes techniques to pursue actively a search for breaks versus adopting a purely speculative approach. Advantages and disadvantages of various techniques are appraised. Intuitively one might argue that an encircling scleral buckle combined with vitrectomy would give higher single operation success than pars plana vitrectomy alone because "undetected" retinal breaks would be addressed by a 360° plombage. We could not confirm this concept. Newer techniques, such as pars plana vitrectomy augmented with dye extrusion or endoscopic-assisted pars plana vitrectomy, show encouraging results. Technological advances such as intraoperative optical coherence tomography will also help to broaden the vitreoretinal surgeon's armamentarium. At this time, there is no gold standard in terms of the recommended

  16. Adverse pathology and undetectable ultrasensitive prostate-specific antigen after radical prostatectomy: is adjuvant radiation warranted?

    Science.gov (United States)

    Simon, Ross M; Howard, Lauren E; Freedland, Stephen J; Aronson, William J; Terris, Martha K; Kane, Christopher J; Amling, Christopher L; Cooperberg, Matthew R; Vidal, Adriana C

    2016-06-01

    To determine if men with adverse pathology but undetectable ultrasensitive (<0.01 ng/mL) PSA are at high-risk for biochemical recurrence (BCR), or if there is a subset of patients at low-risk for whom the benefit of adjuvant radiation therapy might be limited. We evaluated 411 patients treated with RP from 2001 to 2013 without adjuvant radiation who had an undetectable (<0.01 ng/mL) PSA level after RP but with adverse pathology [positive surgical margins (PSMs), extraprostatic extension (EPE), and/or seminal vesicle invasion (SVI)]. Multivariable Cox regression analyses tested the relationship between pathological characteristics and BCR to identify groups of men at highest risk of early BCR. On multivariable analysis, only pathological Gleason 7 (4 + 3), Gleason ≥8, and SVI independently predicted BCR (P = 0.019, P < 0.001, and P = 0.001, respectively), although on two-way analysis men with Gleason 7 (4 + 3) did not have significantly higher rates of BCR compared with patients with Gleason ≤6 (log-rank, P = 0.074). Men with either Gleason ≥8 (with PSMs or EPE) or SVI (15% of the cohort) defined a high-risk group vs men without these characteristics (3-year BCR risk of 50.4% vs 11.9%, log-rank, P < 0.001). Among men with adverse pathology but an undetectable (<0.01 ng/mL) PSA level after RP, the benefits of adjuvant radiation are probably limited except for men with Gleason 8-10 (with PSMs or EPE) or SVI who are at high-risk of early BCR. © 2015 The Authors BJU International © 2015 BJU International Published by John Wiley & Sons Ltd.

  17. CTC-ask: a new algorithm for conversion of CT numbers to tissue parameters for Monte Carlo dose calculations applying DICOM RS knowledge

    DEFF Research Database (Denmark)

    Ottosson, Rickard; Behrens, Claus F.

    2011-01-01

    One of the building blocks in Monte Carlo (MC) treatment planning is to convert patient CT data to MC compatible phantoms, consisting of density and media matrices. The resulting dose distribution is highly influenced by the accuracy of the conversion. Two major contributing factors are precise c...... outside of the lungs for the two cases studied, respectively. This was completely avoided by CTC-ask. CTC-ask is able to reduce anatomically irrational media assignment. The CTC-ask source code can be made available upon request to the authors....

  18. Effect of undetected gravitational lenses on statistical measures of quasar evolution

    International Nuclear Information System (INIS)

    Turner, E.L.

    1980-01-01

    Brightness amplifications by undetected gravitational lenses could be responsible in part for the apparent evolution of quasars, particularly for those which appear to be of high luminosity. It is shown that values of Vover-bar/over-barVover-bar/sub M/> or =0.6 and number-magnitude slopes > or =0.9 need not necessarily imply source density evolution if lensing events are common. Quasar samples which are defined by flux limits and minimum luminosities will preferentially include gravitational lens systems. Even if lensing events are quite rare, a large fraction of the lensed quasars will appear more luminous than the most luminous unlensed quasar

  19. Using High-Dimensional Image Models to Perform Highly Undetectable Steganography

    Science.gov (United States)

    Pevný, Tomáš; Filler, Tomáš; Bas, Patrick

    This paper presents a complete methodology for designing practical and highly-undetectable stegosystems for real digital media. The main design principle is to minimize a suitably-defined distortion by means of efficient coding algorithm. The distortion is defined as a weighted difference of extended state-of-the-art feature vectors already used in steganalysis. This allows us to "preserve" the model used by steganalyst and thus be undetectable even for large payloads. This framework can be efficiently implemented even when the dimensionality of the feature set used by the embedder is larger than 107. The high dimensional model is necessary to avoid known security weaknesses. Although high-dimensional models might be problem in steganalysis, we explain, why they are acceptable in steganography. As an example, we introduce HUGO, a new embedding algorithm for spatial-domain digital images and we contrast its performance with LSB matching. On the BOWS2 image database and in contrast with LSB matching, HUGO allows the embedder to hide 7× longer message with the same level of security level.

  20. Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans

    DEFF Research Database (Denmark)

    Mangino, Massimo; Hwang, Shih-Jen; Spector, Timothy D

    2012-01-01

    (-8)). We also identified two novel genomic regions associated with LTL variation that map near a conserved telomere maintenance complex component 1 (CTC1; rs3027234, P = 3.6 × 10(-8)) on chromosome17p13.1 and zinc finger protein 676 (ZNF676; rs412658, P = 3.3 × 10(-8)) on 19p12. The minor allele of rs...

  1. The human CTC1/STN1/TEN1 complex regulates telomere maintenance in ALT cancer cells

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Chenhui; Jia, Pingping; Chastain, Megan; Shiva, Olga; Chai, Weihang, E-mail: wchai@wsu.edu

    2017-06-15

    Maintaining functional telomeres is important for long-term proliferation of cells. About 15% of cancer cells are telomerase-negative and activate the alternative-lengthening of telomeres (ALT) pathway to maintain their telomeres. Recent studies have shown that the human CTC1/STN1/TEN1 complex (CST) plays a multi-faceted role in telomere maintenance in telomerase-expressing cancer cells. However, the role of CST in telomere maintenance in ALT cells is unclear. Here, we report that human CST forms a functional complex localizing in the ALT-associated PML bodies (APBs) in ALT cells throughout the cell cycle. Suppression of CST induces telomere instabilities including telomere fragility and elevates telomeric DNA recombination, leading to telomere dysfunction. In addition, CST deficiency significantly diminishes the abundance of extrachromosomal circular telomere DNA known as C-circles and t-circles. Suppression of CST also results in multinucleation in ALT cells and impairs cell proliferation. Our findings imply that the CST complex plays an important role in regulating telomere maintenance in ALT cells. - Highlights: • CST localizes at telomeres and ALT-associated PML bodies in ALT cells throughout the cell cycle. • CST is important for promoting telomeric DNA replication in ALT cells. • CST deficiency decreases ECTR formation and increases T-SCE. • CST deficiency impairs ALT cell proliferation and results in multinucleation.

  2. PrediCTC, liquid biopsy in precision oncology: a technology transfer experience in the Spanish health system.

    Science.gov (United States)

    Alonso-Alconada, L; Barbazan, J; Candamio, S; Falco, J L; Anton, C; Martin-Saborido, C; Fuster, G; Sampedro, M; Grande, C; Lado, R; Sampietro-Colom, L; Crego, E; Figueiras, S; Leon-Mateos, L; Lopez-Lopez, R; Abal, M

    2018-05-01

    Management of metastatic disease in oncology includes monitoring of therapy response principally by imaging techniques like CT scan. In addition to some limitations, the irruption of liquid biopsy and its application in personalized medicine has encouraged the development of more efficient technologies for prognosis and follow-up of patients in advanced disease. PrediCTC constitutes a panel of genes for the assessment of circulating tumor cells (CTC) in metastatic colorectal cancer patients, with demonstrated improved efficiency compared to CT scan for the evaluation of early therapy response in a multicenter prospective study. In this work, we designed and developed a technology transfer strategy to define the market opportunity for an eventual implementation of PrediCTC in the clinical practice. This included the definition of the regulatory framework, the analysis of the regulatory roadmap needed for CE mark, a benchmarking study, the design of a product development strategy, a revision of intellectual property, a cost-effectiveness study and an expert panel consultation. The definition and analysis of an appropriate technology transfer strategy and the correct balance among regulatory, financial and technical determinants are critical for the transformation of a promising technology into a viable technology, and for the decision of implementing liquid biopsy in the monitoring of therapy response in advanced disease.

  3. Cerebro-retinal microangiopathy with calcifications and cysts due to recessive mutations in the CTC1 gene.

    Science.gov (United States)

    Bisserbe, A; Tertian, G; Buffet, C; Turhan, A; Lambotte, O; Nasser, G; Alvin, P; Tardieu, M; Riant, F; Bergametti, F; Tournier-Lasserve, E; Denier, C

    2015-05-01

    Cerebro-retinal microangiopathy with calcifications and cysts (CRMCC) or Coats plus syndrome is a pleiotropic disorder affecting the eyes, brain, bone and gastrointestinal tract. Its primary pathogenesis involves small vessel obliterative microangiopathy. Recently, autosomal recessively inherited mutations in CTC1 have been reported in CRMCC patients. We herein report an adolescent referred to our hospital following new seizures in a context of an undefined multisystem disorder. Cerebral imaging disclosed asymmetrical leukopathy, intracranial calcifications and cysts. In addition, he presented other typical CRMCC features i.e. a history of intrauterine growth retardation, skeletal demineralization and osteopenia, bilateral exudative vitreo-retinopathy reminiscent of Coats disease, recurrent gastrointestinal hemorrhages secondary to watermelon stomach and variceal bleeding of the esophagus due to idiopathic portal hypertension and telangiectatic and angiodysplasic changes in the small intestine and colon, and anemia due to recurrent bleeding and bone marrow abnormalities. The patient was diagnosed with Coats plus syndrome. CTC1 gene screening confirmed the diagnosis with the identification of heterozygous deleterious mutations. CRMCC due to CTC1 mutations has a broad clinical expressivity. Our case report illustrates the main possible associated phenotypes and their complications, demonstrating the need for a careful etiological search in order to initiate appropriate therapeutic and preventive measures. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  4. Prevalence of undetected cognitive impairment and depression in residents of an elderly care home.

    Science.gov (United States)

    Al-Jawad, M; Rashid, A K; Narayan, K A

    2007-12-01

    The elderly population in Malaysia is growing rapidly. Some of the most vulnerable are in residential care. Research is needed into the characteristics of this population to aid clinicians and policy makers in addressing the needs of this group. This observational, cross-sectional study aims to determine prevalence of undetected cognitive impairment and depression in elderly care home residents in Malaysia. One hundred and sixty-seven people over 60 years of age living in a state run residential home were interviewed. Validated assessment tools were used to measure dependency, cognitive impairment and depression. The prevalence of probable dementia is 36.5%, with increasing prevalence with age and level of dependence. Prevalence of depression is 67.0% (major depression 13.2%), with more depression in males and in the Indian population. None of the identified cases had been previously investigated or treated for dementia or depression.

  5. The cosmic gorilla effect or the problem of undetected non terrestrial intelligent signals

    Science.gov (United States)

    G. De la Torre, Gabriel; Garcia, Manuel A.

    2018-05-01

    This article points to a long lasting problem in space research and cosmology, the problem of undetected signs of non terrestrial life and civilizations. We intentionally avoid the term extraterrestrial as we consider other possibilities that may arise but not fall strictly within the extraterrestrial scope. We discuss the role of new physics including dark matter and string theory in the search for life and other non terrestrial intelligence. A new classification for non terrestrial civilizations with three types and five dimensions is also provided. We also explain how our own neurophysiology, psychology and consciousness can play a major role in this search of non terrestrial civilizations task and how they have been neglected up to this date. To test this, 137 adults were evaluated using the cognitive reflection test, an attention/awareness questionnaire and a visuospatial searching task with aerial view images to determine the presence of inattentional blindness.

  6. Effects of Motivation: Rewarding Hackers for Undetected Attacks Cause Analysts to Perform Poorly.

    Science.gov (United States)

    Maqbool, Zahid; Makhijani, Nidhi; Pammi, V S Chandrasekhar; Dutt, Varun

    2017-05-01

    The aim of this study was to determine how monetary motivations influence decision making of humans performing as security analysts and hackers in a cybersecurity game. Cyberattacks are increasing at an alarming rate. As cyberattacks often cause damage to existing cyber infrastructures, it is important to understand how monetary rewards may influence decision making of hackers and analysts in the cyber world. Currently, only limited attention has been given to this area. In an experiment, participants were randomly assigned to three between-subjects conditions ( n = 26 for each condition): equal payoff, where the magnitude of monetary rewards for hackers and defenders was the same; rewarding hacker, where the magnitude of monetary reward for hacker's successful attack was 10 times the reward for analyst's successful defense; and rewarding analyst, where the magnitude of monetary reward for analyst's successful defense was 10 times the reward for hacker's successful attack. In all conditions, half of the participants were human hackers playing against Nash analysts and half were human analysts playing against Nash hackers. Results revealed that monetary rewards for human hackers and analysts caused a decrease in attack and defend actions compared with the baseline. Furthermore, rewarding human hackers for undetected attacks made analysts deviate significantly from their optimal behavior. If hackers are rewarded for their undetected attack actions, then this causes analysts to deviate from optimal defend proportions. Thus, analysts need to be trained not become overenthusiastic in defending networks. Applications of our results are to networks where the influence of monetary rewards may cause information theft and system damage.

  7. Utilizing the GentleWave® System for Debridement of Undetected Apical Anatomy.

    Science.gov (United States)

    Ford, Michael W

    2018-03-01

    Debriding and disinfecting complex anatomies within the root canal system pose a major challenge during root canal therapy. Even with current chemomechanical techniques, debris and bacterial remnants are commonly left behind, which are generally believed to increase the risk of endodontic failure. This case details the use of a new technique to debride complex apical anatomy in a maxillary molar. A 48-year-old female presented to the clinic with a chief complaint of increasing pain in her tooth. Clinical examination of the right first maxillary molar (#3) revealed moderate sensitivity to percussion and mild sensitivity to palpation. A pulpal diagnosis of symptomatic irreversible pulpitis and a periapi-cal diagnosis of symptomatic apical periodontitis were made. Mechanical instrumentation was performed using rotary file size #25/.04 for the mesiobuccal and distobuccal canals and size #25/.06 for the palatal canal to create a fluid path and enable obturation of the root canal system following the GentleWave® Procedure. The GentleWave Procedure was completed using Multisonic Ultracleaning™ for complete debridement and disinfection of the root canal system. The tooth was obturated using a warm vertical continuous wave obturation technique. Postoperative radiographs revealed complex anatomy within the apical third that was undetected both during pre-operative radiography and mechanical instrumentation. The palatal canal exhibited a complex apical delta with multiple points of exit, and the mesiobuccal canal revealed an undetected lateral canal within the apical third that had a separate and distinct egress. Conclusion and clinical significance: It is important for the clinician to debride and disinfect complex anatomy within the root canal system to reduce the risk of endodontic failure. This case report highlights the clinical significance of utilizing the GentleWave Procedure for detecting complex apical anatomy during endodontic therapy.

  8. The signature of undetected change: an exploratory electrotomographic investigation of gradual change blindness.

    Science.gov (United States)

    Kiat, John E; Dodd, Michael D; Belli, Robert F; Cheadle, Jacob E

    2018-05-01

    Neuroimaging-based investigations of change blindness, a phenomenon in which seemingly obvious changes in visual scenes fail to be detected, have significantly advanced our understanding of visual awareness. The vast majority of prior investigations, however, utilize paradigms involving visual disruptions (e.g., intervening blank screens, saccadic movements, "mudsplashes"), making it difficult to isolate neural responses toward visual changes cleanly. To address this issue in this present study, high-density EEG data (256 channel) were collected from 25 participants using a paradigm in which visual changes were progressively introduced into detailed real-world scenes without the use of visual disruption. Oscillatory activity associated with undetected changes was contrasted with activity linked to their absence using standardized low-resolution brain electromagnetic tomography (sLORETA). Although an insufficient number of detections were present to allow for analysis of actual change detection, increased beta-2 activity in the right inferior parietal lobule (rIPL), a region repeatedly associated with change blindness in disruption paradigms, followed by increased theta activity in the right superior temporal gyrus (rSTG) was noted in undetected visual change responses relative to the absence of change. We propose the rIPL beta-2 activity to be associated with orienting attention toward visual changes, with the subsequent rise in rSTG theta activity being potentially linked with updating preconscious perceptual memory representations. NEW & NOTEWORTHY This study represents the first neuroimaging-based investigation of gradual change blindness, a visual phenomenon that has significant potential to shed light on the processes underlying visual detection and conscious perception. The use of gradual change materials is reflective of real-world visual phenomena and allows for cleaner isolation of signals associated with the neural registration of change relative to the

  9. Undetected latent failures of safety-related systems. Preliminary survey of events in nuclear power plants 1980-1997

    International Nuclear Information System (INIS)

    Lydell, B.

    1998-03-01

    This report summarizes results and insights from a preliminary survey of events involving undetected, latent failures of safety-related systems. The survey was limited to events where mispositioned equipment (e.g., valves, switches) remained undetected, thus rendering standby equipment or systems unavailable for short or long time periods. Typically, these events were symptoms of underlying latent errors (e.g., design errors, procedure errors, unanalyzed safety conditions) and programmatic errors. The preliminary survey identified well over 300 events. Of these, 95 events are documented in this report. Events involving mispositioned equipment are commonplace. Most events are discovered soon after occurrence, however. But as evidenced by the survey results, some events remained undetected beyond several shift changes. The recommendations developed by the survey emphasize the importance of applying modern root cause analysis techniques to the event analysis to ensure that the causes and implications of occurred events are fully understood

  10. The Association between Leisure-Time Physical Activity and Risk of Undetected Prediabetes

    Science.gov (United States)

    Wang, Jia; Wu, Yili; Ning, Feng; Zhang, Chaoying

    2017-01-01

    Aims. The purpose of the study was to assess the effects of leisure-time physical activity on undetected prediabetes. Methods. Data from the National Health and Nutrition Examination Survey 2007–2012 were used in our analyses. Logistic regression was conducted to estimate the odds ratios (ORs) with 95% confidence intervals (CIs) of prediabetes associated with leisure-time physical activity. Results. A total of 8204 subjects were eligible for our analyses. For all subjects, high level of total leisure-time physical activity (OR = 0.78, 95% CI: 0.66, 0.94) and low level of vigorous leisure-time physical activity (OR = 0.72, 95% CI: 0.58, 0.90) were inversely associated with the risk of prediabetes in multivariate-adjusted model. For subjects under 45 years of age, high level of total leisure-time physical activity (OR = 0.78, 95% CI: 0.61, 0.99) and low (OR = 0.61, 95% CI: 0.45, 0.83) and high (OR = 0.72, 95% CI: 0.53, 1.00) level of vigorous leisure-time physical activity were associated with a decreased risk of prediabetes. In the 45 to 65 age group, only high level of total leisure-time physical activity (OR = 0.73, 95% CI: 0.57, 0.95) had protective effect on prediabetes. Conclusions. Leisure-time physical activity may be associated with a decreased risk of prediabetes. PMID:28367452

  11. Reliability modeling of digital RPS with consideration of undetected software faults

    Energy Technology Data Exchange (ETDEWEB)

    Khalaquzzaman, M.; Lee, Seung Jun; Jung, Won Dea [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Kim, Man Cheol [Chung Ang Univ., Seoul (Korea, Republic of)

    2013-10-15

    This paper provides overview of different software reliability methodologies and proposes a technic for estimating the reliability of RPS with consideration of undetected software faults. Software reliability analysis of safety critical software has been challenging despite spending a huge effort for developing large number of software reliability models, and no consensus yet to attain on an appropriate modeling methodology. However, it is realized that the combined application of BBN based SDLC fault prediction method and random black-box testing of software would provide better ground for reliability estimation of safety critical software. Digitalizing the reactor protection system of nuclear power plant has been initiated several decades ago and now full digitalization has been adopted in the new generation of NPPs around the world because digital I and C systems have many better technical features like easier configurability and maintainability over analog I and C systems. Digital I and C systems are also drift-free and incorporation of new features is much easier. Rules and regulation for safe operation of NPPs are established and has been being practiced by the operators as well as regulators of NPPs to ensure safety. The failure mechanism of hardware and analog systems well understood and the risk analysis methods for these components and systems are well established. However, digitalization of I and C system in NPP introduces some crisis and uncertainty in reliability analysis methods of the digital systems/components because software failure mechanisms are still unclear.

  12. CTC-ask: a new algorithm for conversion of CT numbers to tissue parameters for Monte Carlo dose calculations applying DICOM RS knowledge

    International Nuclear Information System (INIS)

    Ottosson, Rickard O; Behrens, Claus F

    2011-01-01

    One of the building blocks in Monte Carlo (MC) treatment planning is to convert patient CT data to MC compatible phantoms, consisting of density and media matrices. The resulting dose distribution is highly influenced by the accuracy of the conversion. Two major contributing factors are precise conversion of CT number to density and proper differentiation between air and lung. Existing tools do not address this issue specifically. Moreover, their density conversion may depend on the number of media used. Differentiation between air and lung is an important task in MC treatment planning and misassignment may lead to local dose errors on the order of 10%. A novel algorithm, CTC-ask, is presented in this study. It enables locally confined constraints for the media assignment and is independent of the number of media used for the conversion of CT number to density. MC compatible phantoms were generated for two clinical cases using a CT-conversion scheme implemented in both CTC-ask and the DICOM-RT toolbox. Full MC dose calculation was subsequently conducted and the resulting dose distributions were compared. The DICOM-RT toolbox inaccurately assigned lung in 9.9% and 12.2% of the voxels located outside of the lungs for the two cases studied, respectively. This was completely avoided by CTC-ask. CTC-ask is able to reduce anatomically irrational media assignment. The CTC-ask source code can be made available upon request to the authors. (note)

  13. Positive resection margin and/or pathologic T3 adenocarcinoma of prostate with undetectable postoperative prostate-specific antigen after radical prostatectomy: to irradiate or not?

    International Nuclear Information System (INIS)

    Choo, Richard; Hruby, George; Hong, Julie; Hong, Eugene; DeBoer, Gerrit; Danjoux, Cyril; Morton, Gerard; Klotz, Laurence; Bhak, Edward; Flavin, Aileen

    2002-01-01

    Purpose: To evaluate the efficacy of postoperative adjuvant radiotherapy (RT) for positive resection margin and/or pathologic T3 (pT3) adenocarcinoma of the prostate with undetectable postoperative prostate-specific antigen (PSA) levels. Methods and materials: We retrospectively analyzed 125 patients with a positive resection margin and/or pT3 adenocarcinoma of the prostate who had undetectable postoperative serum PSA levels after radical prostatectomy. Seventy-three patients received postoperative adjuvant RT and 52 did not. Follow-up ranged from 1.5 to 12.0 years (median 4.2 for the irradiated group and 4.9 for the nonirradiated group). PSA outcome was available for all patients. Freedom from failure was defined as the maintenance of a serum PSA level of ≤0.2 ng/mL, as well as the absence of clinical local recurrence and distant metastasis. Results: No difference was found in the 5-year actuarial overall survival between the irradiated and nonirradiated group (94% vs. 95%). However, patients receiving adjuvant RT had a statistically superior 5-year actuarial relapse-free rate, including freedom from PSA failure, compared with those treated with surgery alone (88% vs. 65%, p=0.0013). In the irradiated group, 8 patients had relapse with PSA failure alone. None had local or distant recurrence. In the nonirradiated group, 15, 1, and 2 had PSA failure, local recurrence, and distant metastasis, respectively. On Cox regression analysis, pre-radical prostatectomy PSA level and adjuvant RT were statistically significant predictive factors for relapse, and Gleason score, extracapsular invasion, and resection margin status were not. There was a suggestion that seminal vesicle invasion was associated with an increased risk of relapse. The morbidity of postoperative adjuvant RT was acceptable, with only 2 patients developing Radiation Therapy Oncology Group Grade 3 genitourinary complications. Adjuvant RT had a minimal adverse effect on urinary continence and did not cause

  14. Undetected human papillomavirus DNA and uterine cervical carcinoma. Association with cancer recurrence

    International Nuclear Information System (INIS)

    Okuma, Kae; Yamashita, Hideomi; Nakagawa, Keiichi; Yokoyama, Terufumi; Kawana, Kei

    2016-01-01

    The time course of human papillomavirus (HPV) DNA clearance was studied in patients with carcinoma of the cervix during follow-up after primary radical radiotherapy (RT). This study investigated the relationship between timing of HPV clearance and RT effectiveness. A total of 71 consecutive patients who were treated for cervical cancer with primary radical radiotherapy and high-dose rate intracavitary brachytherapy with or without chemotherapy were enrolled in the study. Samples for HPV DNA examination were taken before (1) treatment, (2) every brachytherapy, and (3) every follow-up examination. The times when HPV DNA was undetected were analyzed for association with recurrence-free survival. HPV DNA was not detected in 13 patients (18 %) before RT. Of the 58 patients with HPV DNA detected before treatment, HPV DNA was not detected in 34 % during treatment and in 66 % after the treatment. Within 6 months after RT, HPV DNA was detected in 0 % of all patients. The patients were followed up for a median period of 43 months (range 7-70 months). In all, 20 patients were found to develop recurrence. The 3-year cumulative disease-free survival (DFS) rate was 71 ± 5.4 % for all 71 patients. In multivariate analysis, DFS was significantly associated with HPV (detected vs. not detected) with a hazard ratio of 0.07 (95 % confidence interval 0.008-0.6, p = 0.009). In this study, patients in whom HPV was not detected had the worst prognosis. Six months after RT, HPV DNA was detected in 0 % of the patients. Patients in whom HPV DNA could not be detected before treatment need careful follow-up for recurrence and may be considered for additional, or alternative treatment. (orig.) [de

  15. Undetected cognitive impairment and decision-making capacity in patients receiving hospice care.

    Science.gov (United States)

    Burton, Cynthia Z; Twamley, Elizabeth W; Lee, Lana C; Palmer, Barton W; Jeste, Dilip V; Dunn, Laura B; Irwin, Scott A

    2012-04-01

    : Cognitive dysfunction is common in patients with advanced, life-threatening illness and can be attributed to a variety of factors (e.g., advanced age, opiate medication). Such dysfunction likely affects decisional capacity, which is a crucial consideration as the end-of-life approaches and patients face multiple choices regarding treatment, family, and estate planning. This study examined the prevalence of cognitive impairment and its impact on decision-making abilities among hospice patients with neither a chart diagnosis of a cognitive disorder nor clinically apparent cognitive impairment (e.g., delirium, unresponsiveness). : A total of 110 participants receiving hospice services completed a 1-hour neuropsychological battery, a measure of decisional capacity, and accompanying interviews. : In general, participants were mildly impaired on measures of verbal learning, verbal memory, and verbal fluency; 54% of the sample was classified as having significant, previously undetected cognitive impairment. These individuals performed significantly worse than the other participants on all neuropsychological and decisional capacity measures, with effect sizes ranging from medium to very large (0.43-2.70). A number of verbal abilities as well as global cognitive functioning significantly predicted decision-making capacity. : Despite an absence of documented or clinically obvious impairment, more than half of the sample had significant cognitive impairments. Assessment of cognition in hospice patients is warranted, including assessment of verbal abilities that may interfere with understanding or reasoning related to treatment decisions. Identification of patients at risk for impaired cognition and decision making may lead to effective interventions to improve decision making and honor the wishes of patients and families.

  16. Documentos sobre el X Congreso Nacional de la CTC en 1950 y la persecución sindical en Colombia

    Directory of Open Access Journals (Sweden)

    Eduardo Saenz Rovner

    1991-01-01

    Full Text Available En 1949, los Estado Unidos, como parte de su política anticomunista y antisindical durante la Guerra Fría, presionaron al Ministerio del Trabajo de Colombia, requiriéndole que removiese a aquellos líderes de la Confederación de Trabajadores de Colombia (CTC que el Departamento de Estado norteamericano consideraba comunistas. Ya que el FBI tenía agentes en Colombia recogiendo información sobre las vidas y actividades de los "comunistas" -reales o imaginarios-, era fácil para los norteamericanos señalar a quienes querían ver perseguidos. El Ministerio conservador no quiso ayudar directamente a la Embajada, argumentando con buenas razones, que el Partido Liberal era el que tenía la influencia sobre las facciones "moderadas'' dentro de la CTC. El embajador Willard Beaulac se puso entonces en contacto con el político Carlos Lleras Restrepo y le solicitó que se encargase de coordinar la expulsión de los líderes izquierdistas de la Confederación.

  17. Severe hemolytic disease of fetus and newborn caused by red blood cell antibodies undetected at first-trimester screening (CME).

    Science.gov (United States)

    Dajak, Slavica; Stefanović, Vedran; Capkun, Vesna

    2011-07-01

    The objective was to determine clinical consequences of anti-D and non-D antibodies undetected at first-trimester screening for infant or fetus. This retrospective cohort study included all pregnant women with red blood cell (RBC) antibodies who were tested between 1993 and 2008. Data were obtained from the forms for tracking immunization at the transfusion department. Each form was analyzed for three data sets: the order of screening at which the antibodies were detected (initial or repeated screening), the order of pregnancy (first pregnancy or higher), and whether the antibodies caused severe hemolytic disease of fetus and newborn (HDFN). In D- women, anti-D was detected in 1.3% of cases. The anti-D was undetected in 72 (37%) cases on the first-trimester screening, of which eight cases were complicated by severe HDFN. In this group, three patients were primigravidae. An overall non-D incidence of 0.2% was observed. In 16 cases, non-D were undetected on the first-trimester screening (10 anti-c, two anti-E, two anti-C, one anti-S, and one case of anti-Rh17). Non-D antibodies undetected on initial screening caused 11 cases of severe HDFN (27% of all severe non-D HDFN). Ten of them were in multiparous women. Seven of 11 cases with severe HDFN that were missed were caused by anti-c. The third-trimester screening may detect RBC antibodies that were not present or detected on the first-trimester screening. Such screening may be especially relevant in D+ multiparous women due to the risk of HDFN. © 2010 American Association of Blood Banks.

  18. Microwave ablation assisted by a real-time virtual navigation system for hepatocellular carcinoma undetectable by conventional ultrasonography

    International Nuclear Information System (INIS)

    Liu Fangyi; Yu Xiaoling; Liang Ping; Cheng Zhigang; Han Zhiyu; Dong Baowei; Zhang Xiaohong

    2012-01-01

    Objectives: To evaluate the efficiency and feasibility of microwave (MW) ablation assisted by a real-time virtual navigation system for hepatocellular carcinoma (HCC) undetectable by conventional ultrasonography. Methods: 18 patients with 18 HCC nodules (undetectable on conventional US but detectable by intravenous contrast-enhanced CT or MRI) were enrolled in this study. Before MW ablation, US images and MRI or CT images were synchronized using the internal markers at the best timing of the inspiration. Thereafter, MW ablation was performed under real-time virtual navigation system guidance. Therapeutic efficacy was assessed by the result of contrast-enhanced imagings after the treatment. Results: The target HCC nodules could be detected with fusion images in all patients. The time required for image fusion was 8–30 min (mean, 13.3 ± 5.7 min). 17 nodules were successfully ablated according to the contrast enhanced imagings 1 month after ablation. The technique effectiveness rate was 94.44% (17/18). The follow-up time was 3–12 months (median, 6 months) in our study. No severe complications occurred. No local recurrence was observed in any patients. Conclusions: MW ablation assisted by a real-time virtual navigation system is a feasible and efficient treatment of patients with HCC undetectable by conventional ultrasonography.

  19. Undetected latent failures of safety-related systems. Preliminary survey of events in nuclear power plants 1980-1997

    Energy Technology Data Exchange (ETDEWEB)

    Lydell, B. [RSA Technologies, Vista, CA (United States)

    1998-03-01

    This report summarizes results and insights from a preliminary survey of events involving undetected, latent failures of safety-related systems. The survey was limited to events where mispositioned equipment (e.g., valves, switches) remained undetected, thus rendering standby equipment or systems unavailable for short or long time periods. Typically, these events were symptoms of underlying latent errors (e.g., design errors, procedure errors, unanalyzed safety conditions) and programmatic errors. The preliminary survey identified well over 300 events. Of these, 95 events are documented in this report. Events involving mispositioned equipment are commonplace. Most events are discovered soon after occurrence, however. But as evidenced by the survey results, some events remained undetected beyond several shift changes. The recommendations developed by the survey emphasize the importance of applying modern root cause analysis techniques to the event analysis to ensure that the causes and implications of occurred events are fully understood. 7 refs, 4 tabs, 3 figs. Also available at the SKI Home page: //www.ski.se.

  20. Undetected human papillomavirus DNA and uterine cervical carcinoma. Association with cancer recurrence

    Energy Technology Data Exchange (ETDEWEB)

    Okuma, Kae; Yamashita, Hideomi; Nakagawa, Keiichi [University of Tokyo Hospital, Departments of Radiology, Tokyo (Japan); Yokoyama, Terufumi; Kawana, Kei [University of Tokyo Hospital, Departments Obstetrics and Gynecology, Tokyo (Japan)

    2016-01-15

    The time course of human papillomavirus (HPV) DNA clearance was studied in patients with carcinoma of the cervix during follow-up after primary radical radiotherapy (RT). This study investigated the relationship between timing of HPV clearance and RT effectiveness. A total of 71 consecutive patients who were treated for cervical cancer with primary radical radiotherapy and high-dose rate intracavitary brachytherapy with or without chemotherapy were enrolled in the study. Samples for HPV DNA examination were taken before (1) treatment, (2) every brachytherapy, and (3) every follow-up examination. The times when HPV DNA was undetected were analyzed for association with recurrence-free survival. HPV DNA was not detected in 13 patients (18 %) before RT. Of the 58 patients with HPV DNA detected before treatment, HPV DNA was not detected in 34 % during treatment and in 66 % after the treatment. Within 6 months after RT, HPV DNA was detected in 0 % of all patients. The patients were followed up for a median period of 43 months (range 7-70 months). In all, 20 patients were found to develop recurrence. The 3-year cumulative disease-free survival (DFS) rate was 71 ± 5.4 % for all 71 patients. In multivariate analysis, DFS was significantly associated with HPV (detected vs. not detected) with a hazard ratio of 0.07 (95 % confidence interval 0.008-0.6, p = 0.009). In this study, patients in whom HPV was not detected had the worst prognosis. Six months after RT, HPV DNA was detected in 0 % of the patients. Patients in whom HPV DNA could not be detected before treatment need careful follow-up for recurrence and may be considered for additional, or alternative treatment. (orig.) [German] Gegenstand der Untersuchung war der Zeitverlauf der Eliminierung von humaner Papillomvirus-(HPV-)DNA bei Patienten mit Zervixkarzinomen waehrend der Nachfolgeuntersuchungen nach einer primaeren radikalen Strahlentherapie (RT). Diese Studie untersuchte den Zusammenhang zwischen dem Zeitpunkt der

  1. Effect of quenching and tempering process on sulfide stress cracking susceptibility in API-5CT-C110 casing steel

    Energy Technology Data Exchange (ETDEWEB)

    Liu, M.; Wang, C.H.; Dai, Y.C.; Li, X.; Cao, G.H. [State Key Laboratory of Advanced Special Steel & Shanghai Key Laboratory of Advanced Ferrometallurgy & School of Materials Science and Engineering, Shanghai University, 149 Yanchang Road, Shanghai 200072 (China); Russell, A.M. [Division of Materials Science and Engineering, Ames Laboratory of the U.S.D.O.E., and Department of Materials Science and Engineering, Iowa State University, Ames, IA 50011-2300 (United States); Liu, Y.H.; Dong, X.M. [Tube & Pipe Department, Baosteel Research Institute, Baoshan Iron & Steel Co., Ltd, Shanghai 201900 (China); Zhang, Z.H., E-mail: zhzhang@baosteel.com [Tube & Pipe Department, Baosteel Research Institute, Baoshan Iron & Steel Co., Ltd, Shanghai 201900 (China)

    2017-03-14

    Three quenching and tempering processes performed on API-5CT-C110 casing steel produced tempered martensite structures and similar mechanical properties but distinct sulfide stress cracking (SSC) behavior as evaluated by Double Cantilever Beam (DCB) testing. An as-quenched specimen tempered at 690 °C for two hours showed superior SSC behavior compared to another specimen tempered at 715 °C for one hour. The latter contained a larger fraction of low-angle boundaries (LABs) and higher values of kernel average misorientation (KAM) than those in the former. Moreover, one more quenching and tempering on the former specimen would produce better SSC resistance with a decrease in the fraction of LABs and the values of KAM. Since dislocations trap hydrogen more strongly than grain boundaries, the specimen with higher KAM values, as well as higher dislocation density, would trap more hydrogen atoms and lead to greater SSC.

  2. Undetected angle closure in patients with a diagnosis of open-angle glaucoma.

    Science.gov (United States)

    Varma, Devesh K; Simpson, Sarah M; Rai, Amandeep S; Ahmed, Iqbal Ike K

    2017-08-01

    The aim of this study was to identify the proportion of patients referred to a tertiary glaucoma centre with a diagnosis of open-angle glaucoma (OAG) who were found to have angle closure glaucoma. Retrospective chart review. Consecutive new patients referred for glaucoma management to a tertiary centre between July 2010 and December 2011 were reviewed. Patients whose referrals for glaucoma assessment specified angle status as "open" were included. The data collected included glaucoma specialist's angle assessment, diagnosis, and glaucoma severity. The status of those with 180 degrees or more Shaffer angle grading of 0 was classified as "closed." From 1234 glaucoma referrals, 179 cases were specified to have a diagnosis of OAG or when angles were known to be open. Of these, 16 (8.9%) were found on examination by the glaucoma specialist to have angle closure. Pseudoexfoliation was present in 4 of 16 patients (25%) in the missed angle-closure glaucoma (ACG) group and 22 of 108 patients (13.5%) in the remaining OAG group. There was no difference found in demographic or ocular biometric parameters between those with confirmed OAG versus those with missed ACG. Almost 1 in 11 patients referred by ophthalmologists to a tertiary glaucoma centre with a diagnosis of OAG were in fact found to have angle closure. Given the different treatment approaches for ACG versus OAG, this study suggests a need to strengthen angle evaluations. Copyright © 2017 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights reserved.

  3. Variabilidade espacial de MO, P, K e CTC do solo sob diferentes usos e manejos Spatial variability of MO, P, K and CTC of soil under different use and management conditions

    Directory of Open Access Journals (Sweden)

    Eloiza Gomes Silva Cavalcante

    2007-04-01

    Full Text Available O estudo da variabilidade espacial dos atributos químicos dos solos é particularmente importante em áreas onde o solo está submetido a diferentes manejos. O trabalho foi desenvolvido em Selvíria (MS, com o objetivo de avaliar a variabilidade espacial da matéria orgânica (MO, o fósforo (P, do potássio (K e a capacidade de troca catiônica (CTC em um Latossolo Vermelho distrófico sob diferentes usos e manejos. Os solos foram amostrados em uma malha, com intervalos regulares de 2m, perfazendo um total de 64 pontos, nas profundidades de 0,0-0,1m e 0,1-0,2m, nas seguintes áreas: vegetação natural (cerrado, plantio direto, plantio convencional e pastagem. O sistema de plantio direto apresentou acúmulo significativo de matéria orgânica, fósforo, potássio e elevação da CTC em relação aos demais sistemas estudados, além da melhoria nas condições químicas do solo. A matéria orgânica foi maior em relação ao sistema natural. As maiores variabilidades medidas por meio do coeficiente de variação foram observadas para o fósforo e o potássio, sendo que a matéria orgânica e a CTC apresentaram coeficiente de variação médio nos diferentes usos e manejos do solo.The study of the spatial variability of the chemical attributes of the soils is particularly important in areas where the soil is submitted to different management. This work was developed in Selvíria (MS with the objective of evaluating the spatial variability of the organic matter (MO, phosphorus (P, potassium (K and cation exchange capacity (CEC in a oxisol under different use and management conditions. The soils were collected in a grid, with regular intervals of 2m, total of 64 points, in the depths of 0,0-0,1m and 0,1-0,2m, in the use and management were: native vegetation (savannah, no-tillage, conventional system and pasture. The system of no-tillage presented significant accumulation of organic matter, phosphorus, potassium and elevation of CEC in relation to

  4. More efficient integrated safeguards by applying a reasonable detection probability for maintaining low presence probability of undetected nuclear proliferating activities

    International Nuclear Information System (INIS)

    Otsuka, Naoto

    2013-01-01

    Highlights: • A theoretical foundation is presented for more efficient Integrated Safeguards (IS). • Probability of undetected nuclear proliferation activities should be maintained low. • For nations under IS, the probability to start proliferation activities is very low. • The fact can decrease the detection probability of IS by dozens of percentage points. • The cost of IS per nation can be cut down by reducing inspection frequencies etc. - Abstract: A theoretical foundation is presented for implementing more efficiently the present International Atomic Energy Agency (IAEA) integrated safeguards (ISs) on the basis of fuzzy evaluation of the probability that the evaluated nation will continue peaceful activities. It is shown that by determining the presence probability of undetected nuclear proliferating activities, nations under IS can be maintained at acceptably low proliferation risk levels even if the detection probability of current IS is decreased by dozens of percentage from the present value. This makes it possible to reduce inspection frequency and the number of collected samples, allowing the IAEA to cut costs per nation. This will contribute to further promotion and application of IS to more nations by the IAEA, and more efficient utilization of IAEA resources from the viewpoint of whole IS framework

  5. Myotonic dystrophy type 1: role of CCG, CTC and CGG interruptions within DMPK alleles in the pathogenesis and molecular diagnosis.

    Science.gov (United States)

    Santoro, M; Masciullo, M; Silvestri, G; Novelli, G; Botta, A

    2017-10-01

    Myotonic dystrophy type 1 (DM1) is a multisystem neuromuscular disease caused by a CTG triplet expansion in the 3'-untranslated region (3'-UTR) of DMPK gene. This CTG array is usually uninterrupted in both healthy and DM1 patients, but recent studies identified pathological variant expansions containing unstable CCG, CTC and CGG interruptions with a prevalence of 3-5% of cases. In this review, we will describe the clinical, molecular and genetic issues related to the occurrence of variant expansions associated with DM1. Indeed, the identification of these complex DMPK alleles leads to practical consequences in DM1 genetic counseling and testing, because these exams can give false negative results. Moreover, DM1 patients carrying interrupted alleles can manifest either additional atypical neurological symptoms or, conversely, mild, late-onset forms. Therefore, the prognosis of the disease in these patients is difficult to determine because of the great uncertainty about the genotype-phenotype correlations. We will discuss the putative effects of the variant DM1 alleles on the pathogenic disease mechanisms, including mitotic and meiotic repeats instability and splicing alteration typical of DM1 tissues. Interruptions within the DMPK expanded alleles could also interfere with the chromatin structure, the transcriptional activity of the DM1 locus and the interaction with RNA CUG-binding proteins. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  6. Community Mobilization and Readiness: Planning Flaws which Challenge Effective Implementation of 'Communities that Care' (CTC) Prevention System.

    Science.gov (United States)

    Basic, Josipa

    2015-01-01

    This article reviews the experience of implementing a community approach to drug use and youth delinquency prevention based on the 'Communities that Care' (CTC) system implemented in one Croatian county consisting of 12 communities, 2002 to 2013 (Hawkins, 1999; Hawkins & Catalano, 2004). This overview explores selected critical issues which are often not considered in substance use(r) community intervention planning, implementation as well as in associated process and outcome assessments. These issues include, among others, the mobilization process of adequate representation of people; the involvement of relevant key individual and organizational stakeholders and being aware of the stakeholders' willingness to participate in the prevention process. In addition, it is important to be aware of the stakeholders' knowledge and perceptions about the 'problems' of drug use and youth delinquency in their communities as well as the characteristics of the targeted population(s). Sometimes there are community members and stakeholders who block needed change and therefore prevention process enablers and 'bridges' should be involved in moving prevention programming forward. Another barrier that is often overlooked in prevention planning is community readiness to change and a realistic assessment of available and accessible resources for initiating the planned change(s) and sustaining them. All of these issues have been found to be potentially related to intervention success. At the end of this article, I summarize perspectives from prevention scientists and practitioners and lessons learned from communities' readiness research and practice in Croatian that has international relevance.

  7. A multi-institutional analysis comparing adjuvant and salvage radiation therapy for high-risk prostate cancer patients with undetectable PSA after prostatectomy

    International Nuclear Information System (INIS)

    Budiharto, Tom; Perneel, Christiaan; Haustermans, Karin; Junius, Sara; Tombal, Bertrand; Scalliet, Pierre; Renard, Laurette; Lerut, Evelyne; Vekemans, Kris; Joniau, Steven; Poppel, Hendrik Van

    2010-01-01

    Background and purpose: In men with adverse pathology at the time of radical prostatectomy (RP), the most appropriate timing to administer radiotherapy (RT) remains a subject for debate. To determine whether salvage radiotherapy (SRT) upon early prostate-specific antigen (PSA) relapse is equivalent to immediate adjuvant radiotherapy (ART) post RP. Material and methods: 130 patients receiving ART and 89 receiving SRT were identified. All had an undetectable PSA after RP. Homogeneous subgroups were built based on the status (±) of lymphatic invasion (LVI) and surgical margins (SM), to allow a comparison of ART and SRT. Biochemical disease-free survival (bDFS) was calculated from the date of surgery and from the end of RT. The multivariate analysis was performed using the Cox Proportional hazard model. Results: In the SM-/LVI- and SM+/LVI- groups, SRT was a significant predictor of a decreased bDFS from the date of surgery, while in the SM+/LVI+ group, there was a trend towards significance. From the end of RT, SRT was also a significant predictor of a decreased bDFS in three patient groups: SM-/LVI-, SM+/LVI- and SM+/LVI+. Gleason score >7 showed to be another factor on multivariate analysis associated with decreased bDFS in the SM-/LVI- group, from the date of surgery and end of RT. Preoperative PSA was a significant predictor in the SM-/LVI- group from the date of RP only. Conclusions: Immediate ART post RP for patients with high risk features in the prostatectomy specimen significantly reduces bDFS after RP compared with early SRT upon PSA relapse.

  8. Central memory CD4 T cells are associated with incomplete restoration of the CD4 T cell pool after treatment-induced long-term undetectable HIV viraemia.

    Science.gov (United States)

    Rallón, Norma; Sempere-Ortells, José M; Soriano, Vincent; Benito, José M

    2013-11-01

    It is unclear to what extent T cell reconstitution may be possible in HIV-1-infected individuals on continuous successful highly active antiretroviral therapy (HAART). Herein, we analysed distinct phenotypic markers of immune recovery in patients with undetectable viraemia for 8 years, taking as reference untreated patients and healthy controls. Seventy-two subjects were examined: 28 HIV-1+ patients on successful long-term HAART, 24 HIV-1+ untreated viraemic patients and 20 age-matched healthy controls. Analysis of naive and memory CD4 and CD8 T cells was combined with measurements of activation status (expression of CD38) and with thymic function (expression of CD31). Statistical significance was determined by non-parametric tests. After long-term HAART, the majority of parameters were normalized compared with age-matched control values, including T cell activation and thymic function. However, absolute counts of naive and central memory CD4 T cells remained below normal levels. The only parameters significantly associated with CD4 counts at the end of follow-up were the pre-HAART CD4 count ( β ± SD = 0.54 ± 0.16, P = 0.003) and the level of CD4 central memory cells at the end of follow-up (β ± SD = 1.18 ± 0.23, P 350 cells/mm(3) reached a complete normalization of CD4 counts. Even after long-term successful HAART, complete CD4 restoration may be attainable only in patients starting therapy with moderately high CD4 counts, prompting early initiation of antiretroviral therapy. Incomplete CD4 restoration may be associated with a defective restoration of central memory CD4 T cells, a cell subset with a pivotal role in T cell homeostasis.

  9. Radiofrequency Ablation Assisted by Real-Time Virtual Sonography and CT for Hepatocellular Carcinoma Undetectable by Conventional Sonography

    International Nuclear Information System (INIS)

    Nakai, Motoki; Sato, Morio; Sahara, Shinya; Takasaka, Isao; Kawai, Nobuyuki; Minamiguchi, Hiroki; Tanihata, Hirohiko; Kimura, Masashi; Takeuchi, Nozomu

    2009-01-01

    Real-time virtual sonography (RVS) is a diagnostic imaging support system, which provides the same cross-sectional multiplanar reconstruction images as ultrasound images on the same monitor screen in real time. The purpose of this study was to evaluate radiofrequency ablation (RFA) assisted by RVS and CT for hepatocellular carcinoma (HCC) undetectable with conventional sonography. Subjects were 20 patients with 20 HCC nodules not detected by conventional sonography but detectable by CT or MRI. All patients had hepatitis C-induced liver cirrhosis; there were 13 males and 7 females aged 55-81 years (mean, 69.3 years). RFA was performed in the CT room, and the tumor was punctured with the assistance of RVS. CT was performed immediately after puncture, and ablation was performed after confirming that the needle had been inserted into the tumor precisely. The mean number of punctures and success rates of the first puncture were evaluated. Treatment effects were evaluated with dynamic CT every 3 months after RFA. RFA was technically feasible and local tumor control was achieved in all patients. The mean number of punctures was 1.1, and the success rate of the first puncture was 90.0%. This method enabled safe ablation without complications. The mean follow-up period was 13.5 month (range, 9-18 months). No local recurrence was observed at the follow-up points. In conclusion, RFA assisted by RVS and CT is a safe and efficacious method of treatment for HCC undetectable by conventional sonography.

  10. Undetected rheumatic heart disease revealed using portable echocardiography in a population of school students in Tairawhiti, New Zealand.

    Science.gov (United States)

    Cramp, Geoffrey; Stonehouse, Mary; Webb, Rachel; Webb, Rachel; Chaffey-Aupouri, Gina; Wilson, Nigel

    2012-10-12

    The aim of this programme was to find undetected rheumatic heart disease (RHD) in students from selected schools in the Tairawhiti region (eastern part of the North Island) of New Zealand. Portable echocardiography was used to scan students in 5 urban and rural schools in Tairawhiti where the population is predominantly Maori. The age range of students in the urban schools was 10-13 years and in the rural schools 5-17 years. Those with abnormal echocardiograms were referred for a paediatric consultation, with hospital-based echocardiography if required for the clarification of diagnoses and further management. A total of 685 students, representing over 95% of the schools' students, consented to having echocardiographic scanning. After repeat hospital based echocardiography for 11 students, a total of 52 scans were regarded as abnormal. In this population definite (n=4) or probable (n=7) RHD was found in 11 students a prevalence of 1.61% (95%CIs 0.80-2.85). Possible RHD was found in 19 students. Previously undetected confirmed (n=1) or probable (n=7) RHD was found in 8 students a prevalence of 1.17% (95%CIs 0.51-2.29). Congenital heart defects (CHD) were found in 22 students a prevalence of 3.21% (95%CIs 2.02-4.83). Echocardiography was a popular modality and detected a significant burden of previously unknown RHD in this young Maori population who are now receiving penicillin. However, echocardiography detected a greater prevalence of possible RHD for which optimum management is at present uncertain. Echocardiography also detected students with a range of severity of CHD. Screening with echocardiography for RHD would involve a significant use of public health, paediatric and cardiac resources with 7.6% of students and their families requiring clinical consultations and ongoing management of the abnormal echocardiographic results.

  11. Related factors to atazanavir plasma levels in a cohort of HIV positive individuals with undetectable viral load

    Directory of Open Access Journals (Sweden)

    Ana Júlia Luz

    Full Text Available OBJECTIVE: To evaluate the factors associated with plasma concentrations of atazanavir (ATV in a cohort of well-controlled HIV infected subjects (undetectable viremia. Design: Cross-sectional study where 69 subjects were consecutively enrolled between April and November, 2011. METHODS: Patients had to be on atazanavir for at least six months, undetectable viral load for a period equal to or longer than 12 months, T CD4+ lymphocyte count higher than 200 cells/mm³, and aged between 18 years and 70 years old. Exclusion criteria were pregnancy, any neurologic disease, active opportunistic disease, hepatitis or cancer. Atazanavir plasma levels were measured by ultra-performance liquid chromatography. RESULTS AND DISCUSSION: Overall, 54 patients (mean age of 47 years and 50% women were included in the analysis. Those without ritonavir (unboosted atazanavir had statistically lower plasma concentrations than those with ritonavir boosted atazanavir (p = 0.001 and total and indirect bilirubin were statistically associated with plasma concentration of atazanavir (r = 0.32 and r = 0.33 respectively; p < 0.05 in both cases. no statistical association was found among gender, ethnicity, age, weight, body mass index (BMI, lipid profile, and the plasma concentration of atazanavir. CONCLUSION: in summary, as expected, concomitant ritonavir use was the only factor associated with atazanavir plasma levels. prospective studies with a larger sample size might help to observe an association of atazanavir concentrations to other characteristics such as body weight, since the p-value showed to be close to significance (p = 0.068.

  12. Contribution from Belgium - Belgian contribution to the PWG1 Generic Study on Undetected Failures of Safety systems

    International Nuclear Information System (INIS)

    Vincke, Marc

    1997-01-01

    In the frame of its participation to the PWG 1 generic study on 'Undetected Failures of Safety Systems', AVN performed a search of such cases among the Belgian plants, using the proposed criterion: to find significant events where equipment remained inoperable, or would have been unable to fulfil correctly its safety function for an extended period of time until their condition was discovered. An extended period of time means one cycle duration or several test interval periods at least; if unknown, it has to be estimated w.r.t. plant lifetime. Note that non safety systems preventing safety systems to perform their function are to be included. As a first information source, a screening of AVN's DIANE (Domestic Information about Nuclear Events) database, for undetected failures of safety systems was performed. This database is used to store and retrieve information on a selection of events which have occurred in the Belgian NPPs since 1985. The sources of information are the incident reports which AVN receives from the utilities, completed with the reports of our inspectors on site. The coding system used within this database is based on the IRS Coding Manual. This coding system does not always allow for an easy retrieval of events related to a specific subject. In addition the DIANE-coding system does not allow for direct retrieval of undetected failures. In a first step, the following systems were scanned: reactor coolant system, reactor heat removal system, emergency core cooling system, chemical and volume control, containment spray, main and auxiliary feedwater, component cooling water, control rod drives. For each system, records were selected by examining their title. Careful reading of the 64 reports selected this way finally led to two cases compatible with the criteria. The decennial revision studies formed a second set of information sources. An inquiry to AVN's engineers responsible for the decennial revision projects allowed to

  13. Towards Statistically Undetectable Steganography

    Science.gov (United States)

    2011-06-30

    payload size. Middle, payload proportional to y/N. Right, proportional to N. LSB replacement steganography in never-compressed cover images , detected... Images for Applications in Steganography ," IEEE Trans, on Info. Forensics and Security, vol. 3(2), pp. 247-258, 2008. Conference papers. (1) T. Filler...SPLE, Electronic Imaging , Security, Forensics, Steganography , and Watermarking of Mul- timedia Contents X, San Jose, CA, January 26-31, pp. 11-1-11-13

  14. Usefulness of radioiodine scanning in patients with moderate/high risk differentiated thyroid carcinoma in whom thyroglobulin after thyroxin withdrawal is undetectable after initial treatment

    International Nuclear Information System (INIS)

    Rosario, Pedro Weslley S.; Cardoso, Ludmilla David; Fagundes, Tales Alvarenga; Reis, Janice Sepulveda; Maia, Frederico F. Ribeiro; Purisch, Saulo

    2004-01-01

    We selected 92 patients without anti thyroglobulin antibodies (TgAb), in whom thyroglobulin (Tg) after L-thyroxin withdrawal was undetectable ( 1.5 cm; and lymph nodes metastases in 43 (46.7%), local invasion in 26 (28.2%) or distant metastases in 23 (25%). Control whole-body scanning was negative in 78.2% of the cases and showed cervical uptake in the others. Cases presenting thyroid bed uptake in the absence of tumor recurrence did not receive radioiodine and Tg remained undetectable one year after the initial evaluation in all. Cervical uptake was not observed in 4/13 cases on repeated scan. In contrast, even in the absence of uptake and with undetectable Tg, 7 patients with recurrence confirmed by ultrasound (US) received surgical treatment. US showed 92.8% sensitivity for the detection of local-regional disease. The present study suggests that even moderate/high-risk patients without TgAb and with undetectable T g levels (off T 4 ) do not require radioiodine scanning after initial treatment and can be evaluated by cervical US. (author)

  15. Antiretroviral-treated HIV-1 patients can harbour resistant viruses in CSF despite an undetectable viral load in plasma.

    Science.gov (United States)

    Soulie, Cathia; Grudé, Maxime; Descamps, Diane; Amiel, Corinne; Morand-Joubert, Laurence; Raymond, Stéphanie; Pallier, Coralie; Bellecave, Pantxika; Reigadas, Sandrine; Trabaud, Mary-Anne; Delaugerre, Constance; Montes, Brigitte; Barin, Francis; Ferré, Virginie; Jeulin, Hélène; Alloui, Chakib; Yerly, Sabine; Signori-Schmuck, Anne; Guigon, Aurélie; Fafi-Kremer, Samira; Haïm-Boukobza, Stéphanie; Mirand, Audrey; Maillard, Anne; Vallet, Sophie; Roussel, Catherine; Assoumou, Lambert; Calvez, Vincent; Flandre, Philippe; Marcelin, Anne-Geneviève

    2017-08-01

    HIV therapy reduces the CSF HIV RNA viral load (VL) and prevents disorders related to HIV encephalitis. However, these brain disorders may persist in some cases. A large population of antiretroviral-treated patients who had a VL > 1.7 log 10 copies/mL in CSF with detectable or undetectable VL in plasma associated with cognitive impairment was studied, in order to characterize discriminatory factors of these two patient populations. Blood and CSF samples were collected at the time of neurological disorders for 227 patients in 22 centres in France and 1 centre in Switzerland. Genotypic HIV resistance tests were performed on CSF. The genotypic susceptibility score was calculated according to the last Agence Nationale de Recherche sur le Sida et les hépatites virales Action Coordonnée 11 (ANRS AC11) genotype interpretation algorithm. Among the 227 studied patients with VL > 1.7 log 10 copies/mL in CSF, 195 had VL detectable in plasma [median (IQR) HIV RNA was 3.7 (2.7-4.7) log 10 copies/mL] and 32 had discordant VL in plasma (VL plasma compared with patients with plasma VL > 1.7 log 10 copies/mL. Resistance to antiretrovirals was observed in CSF for the two groups of patients. Fourteen percent of this population of patients with cognitive impairment and detectable VL in CSF had well controlled VL in plasma. Thus, it is important to explore CSF HIV (VL and genotype) even if the HIV VL is controlled in plasma because HIV resistance may be observed. © The Author 2017. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  16. Viral protein Nef is detected in plasma of half of HIV-infected adults with undetectable plasma HIV RNA.

    Directory of Open Access Journals (Sweden)

    Jana Ferdin

    Full Text Available To address the role of translationally active HIV reservoir in chronic inflammation and non-AIDS related disorders, we first need a simple and accurate assay to evaluate viral protein expression in virally suppressed subjects.We optimized an HIV Nef enzyme-linked immunosorbent assay (ELISA and used it to quantify plasma Nef levels as an indicator of the leaky HIV reservoir in an HIV-infected cohort.This study accessed 134 plasma samples from a well-characterized cohort study of HIV-infected and uninfected adults in San Francisco (the SCOPE cohort. We optimized an ELISA for detection of plasma Nef in HIV-negative subjects and HIV-infected non-controllers, and evaluated its utility to quantify plasma Nef levels in a cross-sectional study of ART-suppressed and elite controller HIV-infected subjects.Here, we describe the performance of an optimized HIV Nef ELISA. When we applied this assay to the study cohort we found that plasma Nef levels were correlated with plasma HIV RNA levels in untreated disease. However, we were able to detect Nef in plasma of approximately half of subjects on ART or with elite control, despite the lack of detectable plasma HIV RNA levels using standard assays. Plasma Nef levels were not consistently associated with CD4+ T-cell count, CD8+ T-cell count, self-reported nadir CD4+ T-cell count or the CD4+/CD8+ T-cell ratio in HIV-infected subjects.Since plasma HIV RNA levels are undetectable in virally suppressed subjects, it is reasonable to assume that viral protein expression in leaky reservoir, and not plasma virions, is the source of Nef accumulating in plasma. To examine this further, improvements of the assay sensitivity, by lowering the background through improvements in the quality of Nef antibodies, and detailed characterization of the HIV reservoirs are needed.

  17. Non-real-time computed tomography-guided percutaneous ethanol injection therapy for heapocellular carcinoma undetectable by ultrasonography

    International Nuclear Information System (INIS)

    Ueda, Kazushige; Ohkawara, Tohru; Minami, Masahito; Sawa, Yoshihiko; Morinaga, Osamu; Kohli, Yoshihiro; Ohkawara, Yasuo

    1998-01-01

    The purpose of this study was to evaluate the feasibility of non-real-time CT-guided percutaneous ethanol injection therapy (PEIT) for hepatocellular carcinoma (HCC, 37 lesions) untreatable by ultrasonography-guided (US)-PEIT. The HCC lesion was localized on the lipiodol CT image with a graduated grid system. We advanced a 21 G or 22 G needle in a stepwise fashion with intermittent localization scans using a tandem method to position the tip of the needle in the lesion. Ethanol containing contrast medium was injected with monitoring scans obtained after incremental volumes of injection, until perfusion of the lesion was judged to be complete. A total of 44 CT-PEIT procedures were performed. The average number of needle passes from the skin to the liver in each CT-PEIT procedure was 2.3, the average amount of ethanol injected was 14.4 ml, and the average time required was 49.3 minutes. Complete perfusion of the lesion by ethanol on monitoring CT images was achieved in all lesions with only a single or double CT-PEIT procedure without severe complication. Local recurrence was detected only in 5 lesions. At present, it is more time-consuming to perform CT-PEIT than US-PEIT because conventional CT guidance is not real-time imaging. However, it is expected that this limitation of CT-PEIT will be overcome in the near future with the introduction of CT fluoroscopy. In conclusion, CT-PEIT should prove to be a feasible, acceptable treatment for challenging cases of HCC undetectable by US. (author)

  18. Screening of coeliac disease in undetected adults and patients diagnosed with irritable bowel syndrome in Riyadh, Saudi Arabia.

    Science.gov (United States)

    Al-Ajlan, Abdulrahman S

    2016-07-01

    The present study is to determine the prevalence and implication of coeliac disease (CD) among adult Saudis and compared to those with diagnosed irritable bowel syndrome. This prospective study was conducted among 980 adults. Out of that, 482 subjects (staff and students of Riyadh Health Science College) were designated as control cohorts for undetected coeliac disease. Furthermore, another contingent of 498 subjects diagnosed with irritable bowel syndrome (IBS) at Prince Salman Hospital and Al-Iman General Hospital also constituted a segment of the overall initial 1020 subjects. Both cases and control were tested for serological markers of coeliac disease (tissues transglutaminase (tTGAs) and endomysial autoantibody (EMAs) and were confirmed by histopathology test. All the positive for cases of coeliac disease were screened for iron deficiency anaemia, Vitamin D deficiency, and osteoporosis and weight assessment. The percentage of coeliac disease in control subjects and patients diagnosed with irritable bowel syndrome (IBS) were found to be 1.9% and 9.6% respectively, about 38% of the total coeliac disease patients are among females of middle age (20-39-years) and 16% of the males in the same age range. Whereas, 20% and 25% of all coeliac disease cases with ages of 40-59 were remarked as females and males respectively. The identical nature and overlap of symptoms of the two conditions could possibly result in misdiagnosis of coeliac diseases or over-diagnosis of irritable bowel syndrome. The findings of the study might also give considerable implications of the disease in the nutritional level which is noticeable.

  19. Identification and distribution of three serologically undetected alleles of HLA-DR by oligonucleotide x DNA typing analysis

    International Nuclear Information System (INIS)

    Tiercy, J.M.; Gorski, J.; Jeannet, M.; Mach, B.

    1988-01-01

    Recent progress in the molecular biology of human major histocompatibility complex class II genes (HLA-DP, -DQ, -DR) have shown that the genetic complexity and allelic polymorphism are greater than expected. In the case of HLA-DR, three DR β-chain loci have been identified and linked, two of which (DR βI and DR βIII, now assigned names HLA-DR1B and HLA-DR3B) are functional. The authors have shown that the HLA micropolymorphism detected at the DNA sequence level can easily be analyzed by hybridization with allele-specific oligonucleotides (HLA oligotyping). In the case of the HLA DRw52 supertypic specificity, which includes the DR3, DR5, DRw6, and DRw8 haplotypes, three alleles, referred to as DRw52a, DRw52b, and DRw52c, have recently been identified at the HLA-DR3B locus by DNA sequencing. Hybridization with locus- and allele-specific oligonucleotide probes (designated 52a, 52b, and 52c) has been performed on DNA from normal individuals forming a panel of 82 haplotypes to establish the distribution of these three alleles. Individuals of the DR3 haplotype had either the DRw52a or DRw52b allele, and individuals of extended haplotype HLA-A1,B8,DR3 had only the DRw52a allele. DR5 individuals all had the DRw52b allele, while individuals of DRw6 haplotype had the DRw52a, -52b, or -52c allele. None of these three alleles are found in DRw8 individuals. Analysis of this micropolymorphism, undetectable by common typing procedures, is therefore now operational for more accurate HLA matching for transplantation and for improving correlations between HLA and disease susceptibility

  20. Screening of coeliac disease in undetected adults and patients diagnosed with irritable bowel syndrome in Riyadh, Saudi Arabia

    Directory of Open Access Journals (Sweden)

    Abdulrahman S. Al-Ajlan

    2016-07-01

    Full Text Available The present study is to determine the prevalence and implication of coeliac disease (CD among adult Saudis and compared to those with diagnosed irritable bowel syndrome. This prospective study was conducted among 980 adults. Out of that, 482 subjects (staff and students of Riyadh Health Science College were designated as control cohorts for undetected coeliac disease. Furthermore, another contingent of 498 subjects diagnosed with irritable bowel syndrome (IBS at Prince Salman Hospital and Al-Iman General Hospital also constituted a segment of the overall initial 1020 subjects. Both cases and control were tested for serological markers of coeliac disease (tissues transglutaminase (tTGAs and endomysial autoantibody (EMAs and were confirmed by histopathology test. All the positive for cases of coeliac disease were screened for iron deficiency anaemia, Vitamin D deficiency, and osteoporosis and weight assessment. The percentage of coeliac disease in control subjects and patients diagnosed with irritable bowel syndrome (IBS were found to be 1.9% and 9.6% respectively, about 38% of the total coeliac disease patients are among females of middle age (20–39-years and 16% of the males in the same age range. Whereas, 20% and 25% of all coeliac disease cases with ages of 40–59 were remarked as females and males respectively. The identical nature and overlap of symptoms of the two conditions could possibly result in misdiagnosis of coeliac diseases or over-diagnosis of irritable bowel syndrome. The findings of the study might also give considerable implications of the disease in the nutritional level which is noticeable.

  1. Infrared-faint radio sources remain undetected at far-infrared wavelengths. Deep photometric observations using the Herschel Space Observatory

    Science.gov (United States)

    Herzog, A.; Norris, R. P.; Middelberg, E.; Spitler, L. R.; Leipski, C.; Parker, Q. A.

    2015-08-01

    Context. Showing 1.4 GHz flux densities in the range of a few to a few tens of mJy, infrared-faint radio sources (IFRS) are a type of galaxy characterised by faint or absent near-infrared counterparts and consequently extreme radio-to-infrared flux density ratios up to several thousand. Recent studies showed that IFRS are radio-loud active galactic nuclei (AGNs) at redshifts ≳2, potentially linked to high-redshift radio galaxies (HzRGs). Aims: This work explores the far-infrared emission of IFRS, providing crucial information on the star forming and AGN activity of IFRS. Furthermore, the data enable examining the putative relationship between IFRS and HzRGs and testing whether IFRS are more distant or fainter siblings of these massive galaxies. Methods: A sample of six IFRS was observed with the Herschel Space Observatory between 100 μm and 500 μm. Using these results, we constrained the nature of IFRS by modelling their broad-band spectral energy distribution (SED). Furthermore, we set an upper limit on their infrared SED and decomposed their emission into contributions from an AGN and from star forming activity. Results: All six observed IFRS were undetected in all five Herschel far-infrared channels (stacking limits: σ = 0.74 mJy at 100 μm, σ = 3.45 mJy at 500 μm). Based on our SED modelling, we ruled out the following objects to explain the photometric characteristics of IFRS: (a) known radio-loud quasars and compact steep-spectrum sources at any redshift; (b) starburst galaxies with and without an AGN and Seyfert galaxies at any redshift, even if the templates were modified; and (c) known HzRGs at z ≲ 10.5. We find that the IFRS analysed in this work can only be explained by objects that fulfil the selection criteria of HzRGs. More precisely, IFRS could be (a) known HzRGs at very high redshifts (z ≳ 10.5); (b) low-luminosity siblings of HzRGs with additional dust obscuration at lower redshifts; (c) scaled or unscaled versions of Cygnus A at any

  2. Positive Reinforcement Training for Blood Collection in Grizzly Bears (Ursus arctos horribilis) Results in Undetectable Elevations in Serum Cortisol Levels: A Preliminary Investigation.

    Science.gov (United States)

    Joyce-Zuniga, Nicole M; Newberry, Ruth C; Robbins, Charles T; Ware, Jasmine V; Jansen, Heiko T; Nelson, O Lynne

    2016-01-01

    Training nonhuman animals in captivity for participation in routine husbandry procedures is believed to produce a lower stress environment compared with undergoing a general anesthetic event for the same procedure. This hypothesis rests largely on anecdotal evidence that the captive subjects appear more relaxed with the trained event. Blood markers of physiological stress responses were evaluated in 4 captive grizzly bears (Ursus arctos horribilis) who were clicker-trained for blood collection versus 4 bears who were chemically immobilized for blood collection. Serum cortisol and immunoglobulin A (IgA) and plasma β-endorphin were measured as indicators of responses to stress. Plasma β-endorphin was not different between the groups. Serum IgA was undetectable in all bears. Serum cortisol was undetectable in all trained bears, whereas chemically immobilized bears had marked cortisol elevations (p bears with extensive recent immobilization experience. These findings support the use of positive reinforcement training for routine health procedures to minimize anxiety.

  3. Solitary recurrence of castration-resistant prostate cancer with low or undetectable levels of prostate specific antigen salvaged with local ablative radiation therapy: A case report.

    Science.gov (United States)

    Wang, Chiachien Jake; Ying, James; Kapur, Payal; Wohlfeld, Bryan; Roehrborn, Claus; Kim, Dong W Nathan

    2016-01-01

    Prostate cancer recurrences are usually first detected by increased levels of prostate specific antigen (PSA), and systemic therapy is often initiated if distant metastasis is confirmed. However, low or nearly undetectable levels of PSA in the modern era of ultrasensitive PSA assay may be difficult to interpret in patients with a history of prostate cancer. Deciding whether to initiate additional systemic therapy in limited indolent metastatic disease while balancing the quality of life of the patient and ensuring the oncologic control of the disease may be challenging. In the present study, the case of a biopsy-confirmed solitary spine recurrence of prostate cancer with nearly undetectable but persistent levels of PSA (0.05 ng/ml) is reported. Treatment of the recurrence with local ablative radiotherapy improved the pain experienced by the patient, and reduced his levels of PSA to undetectable limits (<0.05 ng/ml). Repeated imaging analysis, PSA assay and clinical assessment demonstrated durable control of the disease without the requirement for additional systemic treatments. The present case highlighted the importance of initiating appropriate work-up according to the clinical scenario. Local treatment for solitary or oligometastatic recurrence of prostate cancer may enhance the effectiveness of current therapeutic strategies and benefit certain patients.

  4. HIV RNA and proviral HIV DNA can be detected in semen after 6 months of antiretroviral therapy although HIV RNA is undetectable in blood.

    Science.gov (United States)

    Du, Peiwei; Liu, An; Jiao, Yanmei; Liu, Cuie; Jiang, Taiyi; Zhu, Weijun; Zhu, Yunxia; Wu, Hao; Sun, Lijun

    2016-03-01

    The risk of sexual transmission of HIV is strongly correlated with amounts of genital HIV RNA. Few studies have reported amounts of HIV RNA and HIV DNA in semen in HIV-infected Chinese patients undergoing antiviral treatment (ART). In this observational study, the amounts of HIV RNA and HIV DNA in semen were assessed after six months of ART in HIV-infected Chinese individuals, when HIV RNA was undetectable in blood . This study included 19 HIV-infected Chinese men undergoing ART for six months. Amounts of HIV in paired semen and blood samples were assessed using real-time PCR. The C2-V5 region of the HIV envelope (env) genes was cloned and sequenced and genotype and co-receptor usage predicted based on the sequence. It was found that HIV RNA was undetectable in the plasma of most patients (17/19), whereas HIV RNA could be detected in the semen of most patients (16/19). HIV DNA could be detected in both semen and blood. Genetic diversity of HIV between the seminal and blood compartments was identified. Thus, amounts of HIV RNA and HIV DNA remain high in semen of HIV-infected Chinese patients after six months of ART treatment, even when HIV RNA was undetectable in blood. © 2016 The Societies and John Wiley & Sons Australia, Ltd.

  5. The pentose moiety of adenosine and inosine is an important energy source for the fermented-meat starter culture Lactobacillus sakei CTC 494.

    Science.gov (United States)

    Rimaux, T; Vrancken, G; Vuylsteke, B; De Vuyst, L; Leroy, F

    2011-09-01

    The genome sequence of Lactobacillus sakei 23K has revealed that the species L. sakei harbors several genes involved in the catabolism of energy sources other than glucose in meat, such as glycerol, arginine, and nucleosides. In this study, a screening of 15 L. sakei strains revealed that arginine, inosine, and adenosine could be used as energy sources by all strains. However, no glycerol catabolism occurred in any of the L. sakei strains tested. A detailed kinetic analysis of inosine and adenosine catabolism in the presence of arginine by L. sakei CTC 494, a fermented-meat starter culture, was performed. It showed that nucleoside catabolism occurred as a mixed-acid fermentation in a pH range (pH 5.0 to 6.5) relevant for sausage fermentation. This resulted in the production of a mixture of acetic acid, formic acid, and ethanol from ribose, while the nucleobase (hypoxanthine and adenine in the case of fermentations with inosine and adenosine, respectively) was excreted into the medium stoichiometrically. This indicates that adenosine deaminase activity did not take place. The ratios of the different fermentation end products did not vary with environmental pH, except for the fermentation with inosine at pH 5.0, where lactic acid was produced too. In all cases, no other carbon-containing metabolites were found; carbon dioxide was derived only from arginine catabolism. Arginine was cometabolized in all cases and resulted in the production of both citrulline and ornithine. Based on these results, a pathway for inosine and adenosine catabolism in L. sakei CTC 494 was presented, whereby both nucleosides are directly converted into their nucleobase and ribose, the latter entering the heterolactate pathway. The present study revealed that the pentose moiety (ribose) of the nucleosides inosine and adenosine is an effective fermentable substrate for L. sakei. Thus, the ability to use these energy sources offers a competitive advantage for this species in a meat environment.

  6. Health-related quality of life is not impaired in children with undetected as well as diagnosed celiac disease: a large population based cross-sectional study

    Science.gov (United States)

    2014-01-01

    Background Knowledge regarding the health-related quality of life (HRQoL) of children with celiac disease remains limited and inconclusive. We investigated the HRQoL of three groups of 12-year-olds with: i) undetected celiac disease ii) clinically diagnosed celiac disease, and iii) without celiac disease. Methods A school-based cross-sectional multicenter screening study invited 18 325 children, whereof 68% consented to participate. Participants provided a blood sample, which was later analyzed for anti-tissue-tranglutaminase antibodies, and alongside filled in a questionnaire. When anti-tissue-tranglutaminase antibodies were elevated, a small intestinal biopsy verified the screening-detected celiac disease diagnosis. Self-reported HRQoL was measured using Kidscreen, a generic 52 items instrument with proven reliability and validity. Scores were linearly transformed into a 0–100 scale with higher values indicating better HRQoL. Mean values with standard deviations (mean ± SD) were compared, and uni- and multivariate logistic regression models tested the odds of a low HRQoL among children with undetected or diagnosed celiac disease, respectively. Results Children with undetected celiac disease (n = 238) reported similar HRQoL as children without celiac disease (n = 12 037) (83.0 ± 11.0 vs. 82.5 ± 11.3, P = 0.51), and also similar HRQoL (82.2 ± 12.2, P = 0.28) to that of children with diagnosed celiac disease (n = 90), of whom 92% were adherent to treatment. Having undetected celiac disease did not increase the odds of low overall HRQoL, independent of sex, area of residence, study year and occurrence of gastrointestinal symptoms (adjusted odds ratio 0.77, 95% CI 0.54-1.10). Comparable results were seen for diagnosed celiac disease cases (adjusted odds ratio 1.11, 95% CI 0.67-1.85). Conclusion Children with undetected celiac disease reported comparable HRQoL as their peers with diagnosed celiac disease, and those without celiac disease

  7. Prognostic value of serum Epstein-Barr virus antibodies in patients with nasopharyngeal carcinoma and undetectable pretreatment Epstein-Barr virus DNA.

    Science.gov (United States)

    Yao, Ji-Jin; Lin, Li; Jin, Ya-Nan; Wang, Si-Yang; Zhang, Wang-Jian; Zhang, Fan; Zhou, Guan-Qun; Cheng, Zhi-Bin; Qi, Zhen-Yu; Sun, Ying

    2017-08-01

    Epstein-Barr virus (EBV) is closely associated with nasopharyngeal carcinoma (NPC). Serum IgA antibodies against early antigen (EA-IgA) and viral capsid antigen (VCA-IgA) are the most commonly used to screen for NPC in endemic areas. However, the prognostic value of serum EA-IgA and VCA-IgA in patients with NPC is less clear. We hypothesize that serum EA-IgA and VCA-IgA levels have prognostic impact for survival outcomes in NPC patients with undetectable pretreatment EBV (pEBV) DNA. In this series, 334 patients with non-metastatic NPC and undetectable pEBV DNA were included. Serum EA-IgA and VCA-IgA were determined by ELISA. After analysis, serum EA-IgA and VCA-IgA loads correlated positively with T, N, and overall stage (all P 1:120 had significantly inferior 5-year progression-free survival (80.4% vs 89.6%, P = 0.025), distant metastasis-free survival (88.4% vs 94.8%, P = 0.050), and locoregional relapse-free survival (88.4% vs 95.6%, P = 0.023; log-rank test). Multivariable analyses revealed that N stage was the only independent prognostic factor (all P < 0.05), but the VCA-IgA became insignificant. Further analyses revealed that serum VCA-IgA was not an independent prognostic factor in early N (N0-1) or advanced N (N2-3) stage NPC. In summary, although both EA-IgA and VCA-IgA correlate strongly with TNM stage, our analyses do not suggest that these antibodies are prognostic biomarkers in patients with NPC and undetectable pEBV DNA. © 2017 The Authors. Cancer Science published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association.

  8. The safety lie. Severe faults remain undetected for years, known deficiencies have no consequences - and the NPPs are in operation; Die Sicherheits-Luege. Gravierende Fehler bleiben jahrzehntelang unentdeckt, bekannte Defizite ohne Folgen - und die AKW am Netz

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2017-07-15

    The contribution deals with deficiencies of German nuclear power plants with respect to design, old safety standards - as in the case of resistance against aircraft crashes, not implemented safety requirements and undetected failures.

  9. Ophthalmologic abnormalities among students with cognitive impairment in eastern Taiwan: The special group with undetected visual impairment.

    Science.gov (United States)

    Tsao, Wei-Shan; Hsieh, Hsi-Pao; Chuang, Yi-Ting; Sheu, Min-Muh

    2017-05-01

    Students with cognitive impairment are at increased risk of suffering from visual impairment due to refractive errors and ocular disease, which can adversely influence learning and daily activities. The purpose of this study was to evaluate the ocular and visual status among students at the special education school in Hualien. All students at the National Hualien Special Education School were evaluated. Full eye examinations were conducted by a skilled ophthalmologist. The students' medical records and disability types were reviewed. A total of 241 students, aged 7-18 years, were examined. Visual acuity could be assessed in 138 students. A total of 169/477 (35.4%) eyes were found to suffer from refractive errors, including 20 eyes with high myopia (≤-6.0 D) and 16 eyes with moderate hypermetropia (+3.0 D to +5.0 D). A total of 84/241 (34.8%) students needed spectacles to correct their vision, thus improving their daily activities and learning process, but only 15/241 (6.2%) students were wearing suitable corrective spectacles. A total of 55/241 students (22.8%) had ocular disorders, which influenced their visual function. The multiple disability group had a statistically significant higher prevalence of ocular disorders (32.9%) than the simple intellectual disability group (19.6%). Students with cognitive impairment in eastern Taiwan have a high risk of visual impairment due to refractive errors and ocular disorders. Importantly, many students have unrecognized correctable refractive errors. Regular ophthalmic examination should be administered to address this issue and prevent further disability in this already handicapped group. Copyright © 2016. Published by Elsevier B.V.

  10. HIV DNA Is Frequently Present within Pathologic Tissues Evaluated at Autopsy from Combined Antiretroviral Therapy-Treated Patients with Undetectable Viral Loads.

    Science.gov (United States)

    Lamers, Susanna L; Rose, Rebecca; Maidji, Ekaterina; Agsalda-Garcia, Melissa; Nolan, David J; Fogel, Gary B; Salemi, Marco; Garcia, Debra L; Bracci, Paige; Yong, William; Commins, Deborah; Said, Jonathan; Khanlou, Negar; Hinkin, Charles H; Sueiras, Miguel Valdes; Mathisen, Glenn; Donovan, Suzanne; Shiramizu, Bruce; Stoddart, Cheryl A; McGrath, Michael S; Singer, Elyse J

    2016-10-15

    HIV infection treatment strategies have historically defined effectiveness through measuring patient plasma HIV RNA. While combined antiretroviral therapy (cART) can reduce plasma viral load (pVL) to undetectable levels, the degree that HIV is eliminated from other anatomical sites remains unclear. We investigated the HIV DNA levels in 229 varied autopsy tissues from 20 HIV-positive (HIV(+)) cART-treated study participants with low or undetectable plasma VL and cerebrospinal fluid (CSF) VL prior to death who were enrolled in the National Neurological AIDS Bank (NNAB) longitudinal study and autopsy cohort. Extensive medical histories were obtained for each participant. Autopsy specimens, including at least six brain and nonbrain tissues per participant, were reviewed by study pathologists. HIV DNA, measured in tissues by quantitative and droplet digital PCR, was identified in 48/87 brain tissues and 82/142 nonbrain tissues at levels >200 HIV copies/million cell equivalents. No participant was found to be completely free of tissue HIV. Parallel sequencing studies from some tissues recovered intact HIV DNA and RNA. Abnormal histological findings were identified in all participants, especially in brain, spleen, lung, lymph node, liver, aorta, and kidney. All brain tissues demonstrated some degree of pathology. Ninety-five percent of participants had some degree of atherosclerosis, and 75% of participants died with cancer. This study assists in characterizing the anatomical locations of HIV, in particular, macrophage-rich tissues, such as the central nervous system (CNS) and testis. Additional studies are needed to determine if the HIV recovered from tissues promotes the pathogenesis of inflammatory diseases, such as HIV-associated neurocognitive disorders, cancer, and atherosclerosis. It is well-known that combined antiretroviral therapy (cART) can reduce plasma HIV to undetectable levels; however, cART cannot completely clear HIV infection. An ongoing question is

  11. Prevalence of job-related distress and satisfaction in a nationwide cardiology setting: The IANUS - itAliaN cardiologists' Undetected distress Study.

    Science.gov (United States)

    Majani, Giuseppina; Di Tano, Giuseppe; Giardini, Anna; De Maria, Renata; Russo, Giulia; Maestri, Roberto; Marini, Marco; Milli, Massimo; Aspromonte, Nadia

    2016-08-01

    Cardiologists' work distress has been seldom studied. The ItAliaN cardiologists' Undetected distress Study survey was designed to assess prevalence of work distress and satisfaction, and to gain insight into associations among these constructs and socio-demographics and job description. We invited members of our national cardiological society (Associazione Nazionale Medici Cardiologi Ospedalieri) to participate in an anonymous, self-report, exclusively web-based survey, posted on the Associazione Nazionale Medici Cardiologi Ospedalieri website. ItAliaN cardiologists' Undetected distress Study included socio-demographics, job description and a 15-item questionnaire on job-related distress and work satisfaction. Of 7393 invited cardiologists, 1064 completed the survey. Organizational problems and worries about medico-legal controversies were reported by 71% and 49% of participants, respectively; over one-third reported loss of enthusiasm, helplessness, work-life imbalance and lack of control over work. Conversely, 86% felt competent at work, 67% rewarded by the moral/human meaning of their work and 52% satisfied with their professional fulfilment. Factor analysis revealed a meaningful underlying structure including four factors: job strain, positive meaning, emotional fatigue and relational difficulties. Relational difficulties were more frequent in cardiologists working in primary-level than in secondary and tertiary care hospitals (P = 0.017 and P = 0.013, respectively). Interventional cardiologists reported higher positive meaning than those in the clinical inpatients area and outpatient diagnostic settings (P = 0.007 and P = 0.025, respectively) and lower emotional fatigue than subjects in the clinical inpatients area (P = 0.0005). Cardiologists' work distress should be interpreted integrating job-related negative aspects with a reappraisal of protective personal and relational resources, which should be fostered to promote physicians

  12. Classical imaging with undetected light

    Science.gov (United States)

    Cardoso, A. C.; Berruezo, L. P.; Ávila, D. F.; Lemos, G. B.; Pimenta, W. M.; Monken, C. H.; Saldanha, P. L.; Pádua, S.

    2018-03-01

    We obtained the phase and intensity images of an object by detecting classical light which never interacted with it. With a double passage of a pump and a signal laser beams through a nonlinear crystal, we observe interference between the two idler beams produced by stimulated parametric down conversion. The object is placed in the amplified signal beam after its first passage through the crystal and the image is observed in the interference of the generated idler beams. High contrast images can be obtained even for objects with small transmittance coefficient due to the geometry of the interferometer and to the stimulated parametric emission. Like its quantum counterpart, this three-color imaging concept can be useful when the object must be probed with light at a wavelength for which detectors are not available.

  13. Quantum imaging with undetected photons.

    Science.gov (United States)

    Lemos, Gabriela Barreto; Borish, Victoria; Cole, Garrett D; Ramelow, Sven; Lapkiewicz, Radek; Zeilinger, Anton

    2014-08-28

    Information is central to quantum mechanics. In particular, quantum interference occurs only if there exists no information to distinguish between the superposed states. The mere possibility of obtaining information that could distinguish between overlapping states inhibits quantum interference. Here we introduce and experimentally demonstrate a quantum imaging concept based on induced coherence without induced emission. Our experiment uses two separate down-conversion nonlinear crystals (numbered NL1 and NL2), each illuminated by the same pump laser, creating one pair of photons (denoted idler and signal). If the photon pair is created in NL1, one photon (the idler) passes through the object to be imaged and is overlapped with the idler amplitude created in NL2, its source thus being undefined. Interference of the signal amplitudes coming from the two crystals then reveals the image of the object. The photons that pass through the imaged object (idler photons from NL1) are never detected, while we obtain images exclusively with the signal photons (from NL1 and NL2), which do not interact with the object. Our experiment is fundamentally different from previous quantum imaging techniques, such as interaction-free imaging or ghost imaging, because now the photons used to illuminate the object do not have to be detected at all and no coincidence detection is necessary. This enables the probe wavelength to be chosen in a range for which suitable detectors are not available. To illustrate this, we show images of objects that are either opaque or invisible to the detected photons. Our experiment is a prototype in quantum information--knowledge can be extracted by, and about, a photon that is never detected.

  14. BpuAmI: a novel SacI neoschizomer from Bacillus pumilus discovered in an isolate from Amazon Basin, recognizing 5'-GAG¯CTC-3' BpuAmI: um novo neoesquisomero de SacI de Bacillus pumilus descoberta em um isolado oriundo da Bacia Amazônica, reconhecendo 5'-GAG¯CTC-3'

    Directory of Open Access Journals (Sweden)

    Jocelei M. Chies

    2006-03-01

    Full Text Available A strain of Bacillus pumilus was isolated and identified from water samples collected from a small affluent of the Amazon River. Type II restriction endonuclease activity was detected in these bacteria. The enzyme was purified and the molecular weight of the native protein estimated by gel filtration and SDS-PAGE. The optimum pH, temperature and salt requirements were determined. Quality control assays showed the complete absence of "nonspecific nucleases." Restriction cleavage analysis and DNA sequencing of restriction fragments allowed the unequivocal demonstration of 5´GAG¯CTC3´ as the recognition sequence. This enzyme was named BpuAmI and is apparently a neoschizomer of the prototype restriction endonuclease SacI. This is the first report of an isoschizomer and/or neoschizomer of the prototype SacI identified in the genus Bacillus.Uma linhagem de Bacillus pumilus foi isolada e identificada de amostras de águas coletadas em um pequeno Igarapé do Rio Amazonas. Foi detectada atividade de restrição do tipo II nesta bactéria. A enzima foi purificada e o peso molecular da proteína nativa foi estimado por gel filtração e por eletroforese em gel de poliacrilamida. Foram determinados, o pH e temperatura ótimos e as necessidades de sais. Os ensaios do controle de qualidade mostraram uma ausência completa de "nucleases não específicas". As analises das clivagens e o seqüenciamento do DNA dos fragmentos de restrição permitiram uma demonstração inequívoca de que 5´GAG¯CTC 3´ é a seqüência de reconhecimento da enzima. Esta enzima foi denominada de BpuAmI e aparentemente é um neoesquisômero da enzima protótipo SacI. Este é o primeiro relato de um isoesquisômero e/ou neoesquisômero da enzima protótipo SacI identificada no gênero Bacillus.

  15. The best time for surgery on a patient with recurrent pneumothorax and undetectable culprit lesions is at the exact time air leakage is discovered: a case report.

    Science.gov (United States)

    Matsumoto, Yousuke; Hata, Yoshinobu; Makino, Takashi; Koezuka, Satoshi; Otsuka, Hajime; Sugino, Keishi; Isobe, Kazutoshi; Homma, Sakae; Iyoda, Akira

    2016-08-02

    One cause of recurrent spontaneous pneumothorax includes overlooking bullae during a previous surgery for pneumothorax; and the identification of the culprit lesions is necessary for prevention of recurrence. A 28-year-old man was referred to our hospital because of spontaneous right-sided pneumothorax. He underwent video-assisted thoracoscopic surgery, which did not reveal air leakage. The patient was subsequently seen at our hospital for 2 additional episodes of recurrent right-sided pneumothorax. At the third admission we observed intermittent air leakage while the patient was in the sitting position after chest drainage, and we performed surgery. An intraoperative submersion test showed air leakage dorsally from the pleural surface of S(6) and a minute culprit lesion, which were not seen at the first operation and confirmed the leakage site. The area was ligated and coated with regenerated oxidized cellulose mesh and autologous blood. In cases of pneumothorax with repeated recurrence, the best time to perform surgery on the patient with undetectable culprit lesion is the exact time that air leakage is observed.

  16. Circular viral DNA detection and junction sequence analysis from PBMC of SHIV-infected cynomolgus monkeys with undetectable virus plasma RNA

    International Nuclear Information System (INIS)

    Cara, Andrea; Maggiorella, Maria Teresa; Bona, Roberta; Sernicola, Leonardo; Baroncelli, Silvia; Negri, Donatella R.M.; Leone, Pasqualina; Fagrouch, Zahra; Heeney, Jonathan; Titti, Fausto; Cafaro, Aurelio; Ensoli, Barbara

    2004-01-01

    Extrachromosomal forms of human immunodeficiency virus (HIV)-1 can be detected in peripheral blood mononuclear cell (PBMC) from HIV-infected patients in the absence of detectable viral replication and are thought to be a sign of active but cryptic virus replication. No information, however, are available on whether these forms are also present in animal models for acquired immunodeficiency syndrome (AIDS) and on their relation with other methods of detection of virus replication. To this aim, a polymerase chain reaction (PCR) approach was used to detect and analyze unintegrated circular 2-LTR-containing forms in PBMC of simian human immunodeficiency virus (SHIV)89.6P infected cynomolgus monkeys with RNA levels ranging between 1.8x10 6 and less than 50 copies/ml of plasma. 2-LTR forms were detected in 96.5% of monkeys' samples above 50 copies/ml of plasma, whereas they were present in 75.8% of monkeys' samples below 50 copies/ml of plasma. Persistence of unintegrated viral DNA in monkeys with undetectable plasma RNA could indicate either stability in non-dividing cells or ongoing low levels of viral replication in dividing cells

  17. Trospium chloride has no effect on memory testing and is assay undetectable in the central nervous system of older patients with overactive bladder.

    Science.gov (United States)

    Staskin, D; Kay, G; Tannenbaum, C; Goldman, H B; Bhashi, K; Ling, J; Oefelein, M G

    2010-08-01

    Muscarinic receptors in the brain play an important role in cognitive function, especially memory, and there is growing awareness that specific antimuscarinic drugs for overactive bladder (OAB) may have adverse central nervous system (CNS) effects. Selection of an antimuscarinic OAB drug with reduced potential for CNS effects could be especially beneficial in the elderly people, in whom even the modest cognitive impairment may negatively affect independence. The purpose of the study is to determine if trospium chloride is assay detectable in the CNS of older adults with OAB and to assess whether deterioration of memory occurs in these individuals. Twelve cognitively intact older adults (>or=65-75 years old) with OAB were given extended-release trospium chloride 60 mg once daily over a 10-day period to achieve plasma steady-state levels. Standardised memory testing (Hopkins Verbal Learning Test-Revised and Brief Visuospatial Memory Test-Revised) was performed predose and postdose. Cerebrospinal spinal fluid (CSF) and plasma samples were drawn on day 10 and assayed for trospium chloride. Predose (day 0) and postdose (day 10) results on the memory tests were compared using a reliable change index to assess a meaningful change in learning or memory. Trospium chloride levels in all the CSF samples (n = 72) of all participants were assay undetectable (memory testing revealed no significant net drug effect on learning or recall. This is the first study to investigate for the presence of an OAB antimuscarinic in the human brain, performed by assaying for concentrations of trospium chloride and correlating with simultaneous clinical cognitive safety measures. The results of both pharmacological and neuropsychological testing support the hypothesis of a lack of detectable CNS penetration for the quaternary amine trospium chloride.

  18. Partner Disclosure of PrEP Use and Undetectable Viral Load on Geosocial Networking Apps: Frequency of Disclosure and Decisions About Condomless Sex.

    Science.gov (United States)

    Newcomb, Michael E; Mongrella, Melissa C; Weis, Benjamin; McMillen, Samuel J; Mustanski, Brian

    2016-02-01

    Recent advances in biomedical prevention strategies, including pre-exposure prophylaxis (PrEP) and achieving an undetectable viral load (UVL) among HIV-infected persons, show promise in curbing the rising incidence of HIV among men who have sex with men (MSM) in the United States. This mixed-methods study aimed to investigate the frequency with which MSM encounter potential sex partners on geosocial networking apps who disclose biomedical prevention use, and how MSM make decisions about condom use after these disclosures. Participants were recruited through advertisements placed on a large geosocial networking app for MSM. A total of 668 and 727 participants, respectively, responded to questionnaires assessing partner disclosure of PrEP use and UVL. Each questionnaire included an open-ended item assessing reasons for condomless anal sex (CAS) with partners using biomedical prevention. Across both surveys, most respondents encountered potential sex partners who disclosed PrEP use or UVL, and the majority of those who met up with these partners engaged in CAS at least once. Qualitative analyses found that most participants who reported CAS did so after making a calculated risk about HIV transmission. We also describe a novel risk reduction strategy, "biomed-matching," or having CAS only when both individuals use PrEP or have UVL. We report serostatus differences in both quantitative and qualitative findings. Disclosure of PrEP use and UVL is not uncommon among MSM. Many MSM make accurate appraisals of the risks of CAS with biomedical prevention, and mobile apps may aid with disclosing biomedical prevention use.

  19. A FISH-based method for assessment of HER-2 amplification status in breast cancer circulating tumor cells following CellSearch isolation

    Directory of Open Access Journals (Sweden)

    Frithiof H

    2016-11-01

    Full Text Available Henrik Frithiof,1 Kristina Aaltonen,1 Lisa Rydén2,3 1Division of Oncology and Pathology, 2Division of Surgery, Department of Clinical Sciences Lund, Lund University, Lund, 3Department of Surgery, Skåne University Hospital, Malmö, Sweden Introduction: Amplification of the HER-2/neu (HER-2 proto-oncogene occurs in 10%–15% of primary breast cancer, leading to an activated HER-2 receptor, augmenting growth of cancer cells. Tumor classification is determined in primary tumor tissue and metastatic biopsies. However, malignant cells tend to alter their phenotype during disease progression. Circulating tumor cell (CTC analysis may serve as an alternative to repeated biopsies. The Food and Drug Administration-approved CellSearch system allows determination of the HER-2 protein, but not of the HER-2 gene. The aim of this study was to optimize a fluorescence in situ hybridization (FISH-based method to quantitatively determine HER-2 amplification in breast cancer CTCs following CellSearch-based isolation and verify the method in patient samples. Methods: Using healthy donor blood spiked with human epidermal growth factor receptor 2 (HER-2-positive breast cancer cell lines, SKBr-3 and BT-474, and a corresponding negative control (the HER-2-negative MCF-7 cell line, an in vitro CTC model system was designed. Following isolation in the CellSearch system, CTC samples were further enriched and fixed on microscope slides. Immunocytochemical staining with cytokeratin and 4',6-diamidino-2'-phenylindole dihydrochloride identified CTCs under a fluorescence microscope. A FISH-based procedure was optimized by applying the HER2 IQFISH pharmDx assay for assessment of HER-2 amplification status in breast cancer CTCs. Results: A method for defining the presence of HER-2 amplification in single breast cancer CTCs after CellSearch isolation was established using cell lines as positive and negative controls. The method was validated in blood from breast cancer patients

  20. Status epilepticus

    NARCIS (Netherlands)

    Hensiek, AE; Absalom, Anthony

    2006-01-01

    Status epilepticus is defined as epileptic activity that continues for more than 30 minutes as a single seizure or as recurrent seizures without inter-ictal return of consciousness. The seizure activity is usually classified as partial or generalized. Although status epilepticus is an uncommon

  1. Stock Status

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data inform the public of the most recent stock status for all stocks (FSSI and non-FSSI) in the fishery management unit contained in a fishery managment plan....

  2. Compliance status

    International Nuclear Information System (INIS)

    Black, D.G.

    1995-01-01

    This section of the 1994 Hanford Site Environmental Report summarizes the activities conducted to ensure that the Hanford Site is in compliance with federal environmental protection statutes and related Washington State and local environmental protection regulations and the status of Hanford's compliance with these requirements. Environmental permits required under the environmental protection regulations are discussed under the applicable statute

  3. Compliance status

    Energy Technology Data Exchange (ETDEWEB)

    Black, D.G.

    1995-06-01

    This section of the 1994 Hanford Site Environmental Report summarizes the activities conducted to ensure that the Hanford Site is in compliance with federal environmental protection statutes and related Washington State and local environmental protection regulations and the status of Hanford`s compliance with these requirements. Environmental permits required under the environmental protection regulations are discussed under the applicable statute.

  4. STATUS REPORT

    Indian Academy of Sciences (India)

    First page Back Continue Last page Graphics. STATUS REPORT. Raman scattering observed – 90, 135, 180 degrees and back scattering. Traditionally specific angle dependence to learn about polarization response. Learn molecular information from the surface or materials just below the surface (upto 12 mm depth) ...

  5. Current status on performance of CT colonography and clinical indications

    International Nuclear Information System (INIS)

    Laghi, Andrea; Rengo, Marco; Graser, Anno; Iafrate, Franco

    2013-01-01

    CT colonography (CTC) is a robust and reliable imaging test of the colon. Accuracy for the detection of colorectal cancer (CRC) is as high as conventional colonoscopy (CC). Identification of polyp is size dependent, with large lesions (≥10 mm) accurately detected and small lesions (6–9 mm) identified with moderate to good sensitivity. Recent studies show good sensitivity for the identification of nonpolypoid (flat) lesions as well. Current CTC indications include the evaluation of patients who had undergone a previous incomplete CC or those who are unfit for CC (elderly and frail individuals, patients with underlying severe clinical conditions, or with contraindication to sedation). CTC can also be efficiently used in the assessment of diverticular disease (excluding patients with acute diverticulitis, where the exam should be postponed), before laparoscopic surgery for CRC (to have an accurate localization of the lesion), in the evaluation of colonic involvement in the case of deep pelvic endometriosis (replacing barium enema). CTC is also a safe procedure in patients with colostomy. For CRC screening, CTC should be considered an opportunistic screening test (not available for population, or mass screening) to be offered to asymptomatic average-risk individuals, of both genders, starting at age 50. The use in individuals with positive family history should be discussed with the patient first. Absolute contraindication is to propose CTC for surveillance of genetic syndromes and chronic inflammatory bowel diseases (in particular, ulcerative colitis). The use of CTC in the follow-up after surgery for CRC is achieving interesting evidences despite the fact that literature data are still relatively weak in terms of numerosity of the studied populations. In patients who underwent previous polypectomy CTC cannot be recommended as first test because debate is still open. It is desirable that in the future CTC would be the first-line and only diagnostic test for

  6. Current status on performance of CT colonography and clinical indications

    Energy Technology Data Exchange (ETDEWEB)

    Laghi, Andrea, E-mail: andrea.laghi@uniroma1.it [Department of Radiological Sciences, Oncology and Pathology Sapienza – Università di Roma, Polo Pontino, I.C.O.T. Hospital, Via Franco Faggiana 43, 04100 Latina (Italy); Rengo, Marco [Department of Radiological Sciences, Oncology and Pathology Sapienza – Università di Roma, Polo Pontino, I.C.O.T. Hospital, Via Franco Faggiana 43, 04100 Latina (Italy); Graser, Anno [InstitutfürKlinische Radiologie, Klinikumder Ludwig-Maximilians-Universität München, Campus Großhadern, Marchioninistr. 15, 81377 München (Germany); Iafrate, Franco [Department of Radiological Sciences, Oncology and Pathology Sapienza – Università di Roma, Policlinico Umberto I, Viale Regina Elena 324, 00161 Rome (Italy)

    2013-08-15

    CT colonography (CTC) is a robust and reliable imaging test of the colon. Accuracy for the detection of colorectal cancer (CRC) is as high as conventional colonoscopy (CC). Identification of polyp is size dependent, with large lesions (≥10 mm) accurately detected and small lesions (6–9 mm) identified with moderate to good sensitivity. Recent studies show good sensitivity for the identification of nonpolypoid (flat) lesions as well. Current CTC indications include the evaluation of patients who had undergone a previous incomplete CC or those who are unfit for CC (elderly and frail individuals, patients with underlying severe clinical conditions, or with contraindication to sedation). CTC can also be efficiently used in the assessment of diverticular disease (excluding patients with acute diverticulitis, where the exam should be postponed), before laparoscopic surgery for CRC (to have an accurate localization of the lesion), in the evaluation of colonic involvement in the case of deep pelvic endometriosis (replacing barium enema). CTC is also a safe procedure in patients with colostomy. For CRC screening, CTC should be considered an opportunistic screening test (not available for population, or mass screening) to be offered to asymptomatic average-risk individuals, of both genders, starting at age 50. The use in individuals with positive family history should be discussed with the patient first. Absolute contraindication is to propose CTC for surveillance of genetic syndromes and chronic inflammatory bowel diseases (in particular, ulcerative colitis). The use of CTC in the follow-up after surgery for CRC is achieving interesting evidences despite the fact that literature data are still relatively weak in terms of numerosity of the studied populations. In patients who underwent previous polypectomy CTC cannot be recommended as first test because debate is still open. It is desirable that in the future CTC would be the first-line and only diagnostic test for

  7. Late toxicity results of the GORTEC 94-01 randomized trial comparing radiotherapy with concomitant radiochemotherapy for advanced-stage oropharynx carcinoma: comparison of LENT/SOMA, RTOG/EORTC, and NCI-CTC scoring systems

    International Nuclear Information System (INIS)

    Denis, Fabrice; Garaud, Pascal; Bardet, Etienne; Alfonsi, Marc; Sire, Christian; Germain, Thierry; Bergerot, Philippe; Rhein, Beatrix; Tortochaux, Jacques; Oudinot, Patrick; Calais, Gilles

    2003-01-01

    Purpose: To prospectively assess 5-year late toxicity in patients treated by concomitant radiochemotherapy for locally advanced oropharynx carcinoma using three different toxicity scales. Methods and Materials: A total of 226 patients were entered in a Phase III multicenter, randomized trial comparing radiotherapy alone (70 Gy in 35 fractions: Arm A) with concomitant radiochemotherapy (70 Gy in 35 fractions with three cycles of a 4-day regimen containing carboplatin and 5-fluorouracil: Arm B). Five living patients, free of local or distant recurrences, could not be evaluated for late toxicity. Forty-four patients were eligible for late toxicity with a median follow-up of 5 years. Late toxicity was evaluated by the radiation oncologist using a large questionnaire containing 120 mixed items of three scales (NCI-CTC, LENT/SOMA, and RTOG). The data were then transposed on separate scales using corresponding grades. Results: The 5-year overall survival rate was 22% in Arm B and 16% in Arm A (p=0.05). The 5-year locoregional control rate was 48% in Arm B and 25% in Arm A (p=0.002). The spinal cord was not affected by the concomitant adjunct of chemotherapy, and no deaths were caused by late toxicity. Using the three late toxicity scales, 100% of the patients treated with the combined modality (Arm B) developed one or more late complications vs. 94% in the radiotherapy-alone arm (Arm A). The difference was not statistically significant. The most commonly damaged organs (all Grade 1-4) were the salivary glands (100% in Arm B vs. 82% in Arm A, p<0.05), skin (78% vs. 47%, p<0.05), teeth (67% vs. 18%, p<0.05), mucosa (59% vs. 63% p = not significant), and mandible (44% vs. 12%, p<0.05). One or more Grade 3-4 complications occurred in 82% of the patients in Arm B vs. 47% in Arm A (p=0.02) but concerned only the teeth. The correlation between the RTOG and LENT/SOMA scale and between the NCI-CTC and LENT/SOMA scale were low for Grade 1-4 toxicity (near 30%). The transposability

  8. Status Epilepticus

    Science.gov (United States)

    Seinfeld, Syndi; Goodkin, Howard P.; Shinnar, Shlomo

    2016-01-01

    Although the majority of seizures are brief and cause no long-term consequences, a subset is sufficiently prolonged that long-term consequences can result. These very prolonged seizures are termed “status epilepticus” (SE) and are considered a neurological emergency. The clinical presentation of SE can be diverse. SE can occur at any age but most commonly occurs in the very young and the very old. There are numerous studies on SE in animals in which the pathophysiology, medication responses, and pathology can be rigorously studied in a controlled fashion. Human data are consistent with the animal data. In particular, febrile status epilepticus (FSE), a form of SE common in young children, is associated with injury to the hippocampus and subsequent temporal lobe epilepsy (TLE) in both animals and humans. PMID:26931807

  9. CMS Status

    International Nuclear Information System (INIS)

    Dobrzynski, L.

    2007-01-01

    The status of the construction and installation of CMS detector is reviewed. The 4T magnet is cold since end of February 2006. Its commissioning up to the nominal field started in July 2006 allowing a Cosmic Challenge in which elements of the final detector are involved. All big mechanical pieces equipped with muons chambers have been assembled in the surface hall SX5. Since mid July the detector is closed with commissioned HCAL, two ECAL supermodules and representative elements of the silicon tracker. The trigger system as well as the DAQ are tested. After the achievement of the physics TDR, CMS is now ready for the promising signal hunting. (author)

  10. Bibliography of Soviet Laser Developments, Number 77, May - June 1985.

    Science.gov (United States)

    1986-09-01

    CTC) ATPLB Acta physica polonica . Series A CFJOBOQu Fruehjahrsschule Optik: Beitraege zur Optik und Quantenelektronik CICHRIRS International...PMAMA Prikladnaya matematika i mekhanika (CTC) PRTEA Pribory i tekhnika eksperirnenta (CTC) PSSAB Physica status solidi (A). Applied Research (GDR) PSSBB... Physica status solidi (B). Basic Research (GDR) PZTFD Zhurnal tekhnicheskoy fiziki. Pis’ma (CTC) RAELA Radiotekhnika i elektronika (journal, Moskva

  11. Bibliography of Soviet Laser Developments, Number 90, July-August 1987

    Science.gov (United States)

    1988-06-27

    Acta physica polonica . Series A AUONA Acta Universitatis Palackianae Olomucensis. Facultas rerum naturalium. Physica (Olomouc) AVMEB Avtometriya (CTC...translation available) AENGA Atomnaya energiya (CTC) AKZHA Akusticheskiy zhurnal (CTC) APSVC Acta physica slovaca ARAKB Archiwum akustyki (Warsaw) ATPLB...khimiya, mekhanika (Moskva) PRTEA Pribory i tekhnika eksperimenta (CTC) 136 PSSAB Physica status solidi (A). Applied Research (GDR) PSSBB Physica status

  12. Pyridoxine deficiency in adult patients with status epilepticus.

    Science.gov (United States)

    Dave, Hina N; Eugene Ramsay, Richard; Khan, Fawad; Sabharwal, Vivek; Irland, Megan

    2015-11-01

    An 8-year-old girl treated at our facility for superrefractory status epilepticus was found to have a low pyridoxine level at 5 μg/L. After starting pyridoxine supplementation, improvement in the EEG for a 24-hour period was seen. We decided to look at the pyridoxine levels in adult patients admitted with status epilepticus. We reviewed the records on patients admitted to the neurological ICU for status epilepticus (SE). Eighty-one adult patients were identified with documented pyridoxine levels. For comparison purposes, we looked at pyridoxine levels in outpatients with epilepsy (n=132). Reported normal pyridoxine range is >10 ng/mL. All but six patients admitted for SE had low normal or undetectable pyridoxine levels. A selective pyridoxine deficiency was seen in 94% of patients with status epilepticus (compared to 39.4% in the outpatients) which leads us to believe that there is a relationship between status epilepticus and pyridoxine levels. Copyright © 2015 Elsevier Inc. All rights reserved.

  13. L’utilisation de l’approche CTC: quel impact sur la couverture vaccinale lors de la campagne préventive de vaccination contre la méningite A avec le MenAfriVac au Togo en 2014?

    Science.gov (United States)

    Landoh, Dadja Essoya; Kahn, Anna-Léa; Lacle, Anani; Adjeoda, Kodjovi; Saka, Bayaki; Yaya, Issifou; Nassoury, Danladi Ibrahim; Kalao, Assima; Makawa, Makawa-Sy; Biey, Nsiari-Mueyi Joseph; Bita, Andre; Toke, Yaovi Temfa; Dörte, Petit; Imboua, Lucile; Ronveaux, Olivier

    2017-01-01

    Introduction Une campagne de vaccination contre la méningite A avec le vaccin MenAfriVac a été organisée dans les quatre régions septentrionales du Togo du 28 novembre au 07 décembre 2014. L'approche CTC a été utilisée pour la première fois à une grande échelle pour la campagne de vaccination dans dix districts sanitaires du Togo. L'objectif de cette étude était d'estimer la couverture vaccinale et, de déterminer l'effet de l'utilisation de la Chaîne à Température Contrôlée (CTC) sur ces couvertures vaccinales. Méthodes L'enquête s'est déroulée du 9 au 14 mars 2015, soit environ 3 mois après la fin de la campagne de vaccination dans ces quatre régions. Le sondage en grappe à deux degrés stratifiés selon les régions a été utilisé. Dans 10 districts, le Togo a fait le choix d'utiliser le vaccin MenAfriVac en CTC. Résultats Au total, 2707 ménages ont été enquêtés et 9082 personnes âgées de 1 à 29 ans ont été interviewées. L'âge moyen des personnes enquêtées était de 11,8±7,7 ans et le sex-ratio (H/F) de 1,01. Le nombre moyen de personnes par ménage était de 5,7 et celui des personnes de 1 à 29 ans ciblées par la campagne était de 3,4. Sur les 9082 personnes enquêtées, 8889 (98%) étaient vaccinées. En analyse multivariée, les facteurs associés à la couverture vaccinale avec le MenAfrivac étaient la résidence dans la zone au moment de la campagne (aOR = 4,52 ; 95%IC = [4.07 - 4.97]) et le fait d'être informé de la campagne avant son démarrage (aOR=2,42 ; 95%IC = [2.05 - 2.80]). Par contre, la couverture vaccinale n'était pas différente selon la zone ayant utilisé l'approche CTC ou non (aOR=0,09 ; 95%IC = [-0,27-0,45]). Deux cent sept personnes interrogées (2,3%) ont déclaré avoir eu une Manifestation Adverse Post Immunisation (MAPI) après l'administration du vaccin. Il s'agissait surtout de MAPI mineures à type de fièvre, d'abcès et de gonflement au point d'injection. Conclusion Les r

  14. Undetectable quantum transfer through a continuum

    Energy Technology Data Exchange (ETDEWEB)

    Ping, Jing; Ye, Yin [State Key Laboratory for Superlattices and Microstructures, Institute of Semiconductors, Chinese Academy of Sciences, P.O. Box 912, Beijing 100083 (China); Xu, Luting [Department of Physics, Beijing Normal University, Beijing 100875 (China); Li, Xin-Qi, E-mail: xqli@red.semi.ac.cn [State Key Laboratory for Superlattices and Microstructures, Institute of Semiconductors, Chinese Academy of Sciences, P.O. Box 912, Beijing 100083 (China); Department of Physics, Beijing Normal University, Beijing 100875 (China); Yan, YiJing [Department of Chemistry, Hong Kong University of Science and Technology, Kowloon (Hong Kong); Gurvitz, Shmuel [Beijing Computational Science Research Center, Beijing 100084 (China); Department of Particle Physics and Astrophysics, Weizmann Institute of Science, Rehovot 76100 (Israel)

    2013-03-15

    We demonstrate that a quantum particle, initially prepared in a quantum well, can propagate through a reservoir with a continuous spectrum and reappear in a distant well without being registered in the reservoir. It is shown that such a passage through the reservoir takes place even if the latter is continuously monitored. We discuss a possible experimental realization of such a teleportation phenomenon in mesoscopic systems.

  15. Homegrown violent extremists: A seemingly undetectable threat

    Energy Technology Data Exchange (ETDEWEB)

    Crawford, Justin

    2017-04-01

    With today’s unlimited and instantaneous communication, it is easy for a United States citizen to easily connect with anyone in the world. There are many positives to this; however, the unintended consequences include vulnerable people being influenced by radical ideologies. This is evident with the increase in homegrown violent extremists (HVE).The challenge for law enforcement is how to work with constitutional constraints that require a criminal predicate to be present in order to allow intelligence teams to continue collecting information in a permanent file.

  16. CTC Sentinel. Volume 6, Issue 3

    Science.gov (United States)

    2013-03-01

    century mausoleums and shrines, including the tombs of Sidi Mahmoud, Sidi Moctar, and Alpha Moya in Timbuktu. The shrines are part of the UNESCO...them: Makhtab-al-Khidamat, the al-Haramain Foundation, the Armed Islamic Group, Egyptian Islamic Jihad, Jemaah Islamiya, al-Gama`a al-Islamiyya...religion. Yet during Maumoon Abdul Gayoom’s three- decade autocratic rule, the Egyptian - trained religious scholar enacted a number of measures that

  17. CTC Sentinel. Volume 5, Issue 9

    Science.gov (United States)

    2012-09-01

    demands of the perpetrators of the violence are more holistic and nihilistic. This evolution presents different problems for the GNC in its...enough food .14 This was in large part due to the militia’s refusal of foreign aid, which it saw as an attempt to undermine its authority and help...along the lines of competing national- level mujahidin parties with provincial franchises . Membership in these parties was not primarily based on

  18. CTC Sentinel. Volume 3, Issue 4

    Science.gov (United States)

    2010-04-01

    cultural centers nearby, or as a last minute change in strategy based on the size of the crowd at the restaurant . After the attack, a flurry of...Temple blast in Varanasi and the May 2007 twin blasts in Hyderabad. In March 2008, the U.S. blacklisted HuJI’s Bangladesh franchise as a global...the French Club restaurant , a police station and a girls’ school. Another report said that the men wanted to kidnap Jordan’s ambassador to

  19. CTC Sentinel. Volume 6, Issue 1

    Science.gov (United States)

    2013-01-01

    Verfassungsschutzbericht 2011,” Bundesamt für Ver- fassungsschutz, June 2012. The report distinguishes be- tween Salafists, al-Qa`ida and franchises , and regional jihadist...Unity and Jihad in West Africa. – AP, November 3 November 3, 2012 (SOMALIA): Two suicide bombers targeted the Vil lage restaurant and café near...Mogadishu’s Soobe intersection, ki l l ing at least one person. The restaurant is frequented by government off icials and members of the

  20. CTC Sentinel. Volume 6, Issue 10

    Science.gov (United States)

    2013-10-01

    and the office of Kenyan President Uhuru Kenyatta.11 Fighting continued into the evening of Tuesday , 6 Daniel Howden, “Terror in Nairobi: The Full...provided Iraq with $1 billion per month starting in 1982. See John Bulloch and Harvey Morris , The Gulf War: Its Origins, History and Consequences (London...Expected,” UN High Commissioner for Refu- gees, September 5, 2013. 25 Biro. 26 Loveday Morris , Joby Warrick and Souad Mekhen- net, “Rival al-Qaeda

  1. CTC Sentinel. Volume 8, Issue 2

    Science.gov (United States)

    2015-02-01

    dominated by the Philippine military until 2010. The Philippines is confronted with the most diverse set of internal security challenges in... diversity of Philippine terrorist groups. In 2002, Indonesia suffered 43 terrorist attacks compared to 48 attacks in the Philippines . In 2007...ideology is not directly to blame for the increase in child combatants. Most Communist insurgencies during the Cold War either used children in com- bat

  2. CTC Sentinel. Volume 3, Issue 6

    Science.gov (United States)

    2010-06-01

    disen- franchised and either appealed to its irredentist rejection of the foreign presence—in the case of suicide bombers, for instance—or searching...Investigative Committee said in a website statement that the blast occurred near an outdoor cafe that served as a cultural center. A renowned Chechen

  3. CTC Sentinel. Volume 8, Issue 5

    Science.gov (United States)

    2015-05-01

    particular the largely Sunni landowning and urban merchant classes that dominated the economy. They viewed Alawites as culturally backward and the...Lashkar-i-Tayyiba operatives to conduct the 2008 Mumbai attacks that resulted in approximately 160 civilian fatalities. Al-Filistini provides links to...State’s military achievements have taken place largely along two preexisting, culturally defined fault lines. The first is between the primarily

  4. CTC Sentinel. Volume 5, Issue 3

    Science.gov (United States)

    2012-03-01

    planning or execution of the July 22 attacks.” 9 to his mother’s home to upload the movie trailer on YouTube. He claims that he wrote the last message...Dahdah (whose real name is Imad Eddin Barakat Yar- kas) became the cell leader in 1995 once Saleh moved to Peshawar to help in al-Qa`ida’s reception of

  5. CTC Sentinel. Volume 9, Issue 9

    Science.gov (United States)

    2016-09-01

    what they can do and how they can play a role in the international architecture , and help ensure that we can share information very quickly so that...ties with al-Qa`ida since 2013, but had consistently come up against strong resistance, par- ticularly from Jordanian and Egyptian members of the...talks.9 One of these individuals, Egyptian national Rifai Taha, was killed in a U.S. drone strike in April,10 although one Islamist source told this

  6. CTC Sentinel. Volume 4, Issue 8

    Science.gov (United States)

    2011-08-01

    the al-Qa`ida franchises in Saudi Arabia and Yemen merged after the Saudi branch had been effectively repressed by Saudi authorities. Bin Ladin...back into a deadly force relatively quickly. The group’s ability to recover from adversity demonstrates that al-Qa`ida franchises are adept at...suffers from numerous other challenges that divert attention from AQAP. It is running out of both oil and water, it has a huge unemployment and

  7. CTC Sentinel. Volume 10, Issue 3

    Science.gov (United States)

    2017-03-01

    criminal offenses) with significant differences in their delinquent behavior before and after their Islamist radicalization. Prior to Islamist...to Germany or who was born as a foreigner in Germany.” See Bundesamt für Statistik (Federal Statistical Office) for further details. f This is as

  8. CTC Sentinel. Volume 9, Issue 7

    Science.gov (United States)

    2016-07-01

    which double digits left. Jihadi mobilization in Germany is a mainly ur- ban phenomenon. Ninety percent of those who traveled to Syria or attempted to...when neither the United States nor our partners are in a position to capture him before he carries out a plot,” the president said, “his citizenship ...popular figures can live on digitally as they never could before. The number of hits for “An- war al-Awlaki” on YouTube climbed from 40,000 in 2013 to over

  9. CTC Sentinel. Volume 1, Issue, July 2008

    Science.gov (United States)

    2008-07-01

    operations, asking Bin Ladin, “How much blood has been spilt? How many innocent people, children, elderly , and women have been killed…in the name of...example, c laimed in July 2007 that Shaykh `Isa suffered a stroke and was “ bedridden and seriously i l l .” 29 Shahzad also claimed that `Isa

  10. CTC Sentinel. Volume 7, Issue 7

    Science.gov (United States)

    2014-07-01

    Involvement in Mehran Base Attack,” Dawn, December 14, 2011; “ Punjabi Taliban Be- hind Major Attacks,” The News International, December 15, 2011. On...Afghanistan, and has joined hands with other groups such as the Haqqani network, Hafiz Gul Bahadar’s faction, and some factions in the Punjabi Taliban to...strikes have reduced al- Qa`ida’s presence in the Waziristan area. Khan Said and his group have close ties to the Haqqani network and the Punjabi

  11. CTC Sentinel. Volume 5, Issue 7

    Science.gov (United States)

    2012-07-01

    their lectures and jihadist literature. Many of these students joined the so-called Punjabi Taliban and later lost their lives in U.S. drone...training in the Miran Shah area of North Waziristan Agency.16 The accused told interrogators that in 2007 they created a group called the “ Punjabi ...13 “ Punjabi Muhahideen Involved in KU Blast Held,” The News International, January 14, 2011. 14 Tahir Siddique, “Dr Akmal Facing Trial in UAE

  12. CTC Sentinel. Volume 7, Issue 5

    Science.gov (United States)

    2014-05-01

    Province.27 Several eyewitnesses to the Islamabad court attack in Islamabad reported hearing the militants speaking Punjabi to one another.28 This...Threaten Pakistan Peace Talks,” Agence France-Presse, March 9, 2014. 28 Ibid. 29 TTP Punjab, also called the Punjabi Taliban, is a loose...conglomeration of members of different banned militant groups of Punjabi origin who have developed connec- tions to the TTP and al-Qa`ida. 30 Fasihur Rehman

  13. CTC-Endothelial Cell Interactions during Metastasis

    Science.gov (United States)

    2014-06-01

    equipped with a Zeiss AxioCam MRm camera . A syringe pump (KDS 230, IITC Life Science, Woodland Hills, CA) was used to control the shear stress of the...HUVECs in 2 ml growth medium at 180 x g for 5 min. Measure the cell concentration using a neubauer hemocytometer and prepare 107 HUVEC cells/100 µl...selectin (R&D Systems, Minneapolis, MN). Coated microtubes were mounted on an inverted microscope equipped with a Zeiss AxioCam MRm camera . A syringe pump

  14. CTC Sentinel. Volume 9, Issue 8

    Science.gov (United States)

    2016-08-01

    Corporation , 2016; Julian Pecquet, “ Fundamental fallacy’ in Obama’s plan to arm Syrian rebels?” Al-Monitor, September 16, 2014. 13 Abdallah al-Othman...description of U.S. and coalition efforts to go after the Islamic State’s finances . On other topics, Matthew Levitt documents Hezbollah’s increasingly...Jacob Shapiro, “Bureaucratic Terrorists: Al-Qa’ida in Iraq’s Management and Finances ,” in Brian Fishman ed., Bombers, Bank Accounts, & Bleed- out: al

  15. CTC Sentinel. Volume 7, Issue 3

    Science.gov (United States)

    2014-03-01

    Greece, the United Kingdom, Russia, Mexico, Chile , Argentina, Indonesia and other countries.38 In May 2012, two months before the start of the...universities, immigration detention centers and other targets. In particular, in December 2009 a rudimentary bomb partially exploded at night at Bocconi...University, a prestigious private university in Milan,42 while a letter bomb was sent to an immigration detention center in the northeastern town of

  16. Usefulness of radioiodine scanning in patients with moderate/high risk differentiated thyroid carcinoma in whom thyroglobulin after thyroxin withdrawal is undetectable after initial treatment; Valor da varredura com radioiodo em pacientes com carcinoma diferenciado de tireoide de moderado/alto risco com tireoglobulina (sem tiroxina) indetectavel apos o tratamento inicial

    Energy Technology Data Exchange (ETDEWEB)

    Rosario, Pedro Weslley S.; Cardoso, Ludmilla David; Fagundes, Tales Alvarenga; Reis, Janice Sepulveda; Maia, Frederico F. Ribeiro; Purisch, Saulo [Santa Casa de Belo Horizonte, MG (Brazil). Dept. de Tireoide. Servico de Endocrinologia e Metabologia]. E-mail: cepcem.bhz@terra.com.br

    2004-06-01

    We selected 92 patients without anti thyroglobulin antibodies (TgAb), in whom thyroglobulin (Tg) after L-thyroxin withdrawal was undetectable (<1 ng/ml) 6-12 months after initial therapy and who were considered to be at moderate / high risk for recurrence by this criteria: age {>=}45 years; tumor size >1.5 cm; and lymph nodes metastases in 43 (46.7%), local invasion in 26 (28.2%) or distant metastases in 23 (25%). Control whole-body scanning was negative in 78.2% of the cases and showed cervical uptake in the others. Cases presenting thyroid bed uptake in the absence of tumor recurrence did not receive radioiodine and Tg remained undetectable one year after the initial evaluation in all. Cervical uptake was not observed in 4/13 cases on repeated scan. In contrast, even in the absence of uptake and with undetectable Tg, 7 patients with recurrence confirmed by ultrasound (US) received surgical treatment. US showed 92.8% sensitivity for the detection of local-regional disease. The present study suggests that even moderate/high-risk patients without TgAb and with undetectable T g levels (off T{sub 4}) do not require radioiodine scanning after initial treatment and can be evaluated by cervical US. (author)

  17. Comparison between Roche and Xpert in HIV-1 RNA quantitation: A high concordance between the two techniques except for a CRF02_AG subtype variant with high viral load titters detected by Roche but undetected by Xpert.

    Science.gov (United States)

    Avidor, Boaz; Matus, Natalia; Girshengorn, Shirley; Achsanov, Svetlana; Gielman, Simona; Zeldis, Irene; Schweitzer, Inbal; Adler, Amos; Turner, Dan

    2017-08-01

    HIV-1 viral load (VL) testing is important to predict viral progression and to monitor the response to antiretroviral therapy. New HIV-1 VL tests are continuously introduced to the market. Their performance is usually compared to Abbott and/or Roche HIV-1 VL assays, as reference. The Xpert HIV-1 VL test was recently introduced, but its performance compared to Roche has not been sufficiently studied. To compare the Xpert assay with Roche and to assess its use in the HIV clinical laboratory. A total of 383 plasma samples of HIV-1 infected patients previously tested by Roche, were retrospectively tested by Xpert to determine concordance between the two assays. Samples included a diversity of HIV-1 subtypes and a wide range of VLs. There was a high concordance between the two assays, except for a CRF02_AG subtype variant with high VL titters, that was detected by Roche but undetected by Xpert. The 5' long terminal repeat gene region of this virus, targeted by the Xpert assay, was amplified and sequenced. A 25 nucleotide insert was identified, but was unmatched to any known sequences of HIV-1. This particular insert, however could not explain the false-negativity by the Xpert assay. This study underlines the challenge to routine VL testing due to the high genetic diversity of HIV-1. Clinicians should, therefore be advised that a negative VL in cases where the clinical picture does not match the laboratory report, might in fact be, a false-negative result of the VL assay. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Innovations, status, and networks

    NARCIS (Netherlands)

    P. Wang (Pengfei)

    2016-01-01

    markdownabstractTo obtain and maintain competitive advantage, firms need to implement appropriate innovation strategies (i.e. exploration or exploitation) and acquire status in external networks. In this dissertation, I investigate how innovation strategy, status, and network structure jointly

  19. USCIS My Case Status

    Data.gov (United States)

    Department of Homeland Security — USCIS provide a way for the public who applied for U.S. citizenship to check the status of their application online. To view the status of a case, the application...

  20. Service Level Status

    CERN Multimedia

    Lopienski, S

    2007-01-01

    Nowadays, IT departments provide, and people use, computing services of an increasingly heterogeneous nature. There is thus a growing need for a status display that groups these different services and reports status and availability in a uniform way. The Service Level Status (SLS) system addresses these needs by providing a web-based display that dynamically shows availability, basic information and statistics about various IT services, as well as the dependencies between them.

  1. SIS - Status Determination

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Status Determination dataset within the Species Information System (SIS) contains information related to overfishing, overfished, and approaching overfished...

  2. Pediatric Status Epilepticus Management

    Science.gov (United States)

    Abend, Nicholas S; Loddenkemper, Tobias

    2014-01-01

    Purpose of Review This review discusses management of status epilepticus in children including both anticonvulsant medications and overall management approaches. Recent Findings Rapid management of status epilepticus is associated with a greater likelihood of seizure termination and better outcomes, yet data indicate there are often management delays. This review discusses an overall management approach aiming to simultaneously identify and manage underlying precipitant etiologies, administer anticonvulsants in rapid succession until seizures have terminated, and identify and manage systemic complications. An example management pathway is provided. Summary Status epilepticus is a common neurologic emergency in children and requires rapid intervention. Having a predetermined status epilepticus management pathway can expedite management. PMID:25304961

  3. CTC Sentinel. Volume 1, Issue 1, December 2007. West Point Releases First Issue of CTC Sentinel

    Science.gov (United States)

    2007-12-01

    ideologues themselves. A common categorization of Salafism is Quintan Wiktorowicz’s typology that divides Salafism into three currents: purists...implemented.4 While a useful starting point, the typology provides 2 For his biography, see Brynjar Lia, Architect of Global Jihad: The Life of...Sayyid Imam, in judging whether or not to employ violence, particularly against an Islamic government or foreign tourists , one must always consider

  4. Fighting status inequalities

    DEFF Research Database (Denmark)

    Nielsen, Morten Ebbe Juul; Landes, Xavier

    2016-01-01

    Status inequalities seem to play a fairly big role in creating inequalities in health. This article assumes that there can be good reasons to fight status inequalities in order to reduce inequalities in health. It examines whether the neorepublican ideal of non-dominance does a better job as a th...

  5. Morocco: Country Status Report.

    Science.gov (United States)

    McFerren, Margaret

    A survey of the status of language usage in Morocco begins with an overview of the distribution and usage of Arabic, the official language, the Berber dialects, and French, an unofficial second language. The continuing high status and widespread use of French despite arabization efforts is discussed. A matrix follows that rates these languages and…

  6. Adolescent Weight Status

    DEFF Research Database (Denmark)

    Hjort Kjelldgaard, Heidi; Holstein, Bjørn Evald; Due, Pernille

    2017-01-01

    day) communication with friends through cellphones, SMS messages, or Internet (1.66, 1.03-2.67). In the full population, overweight/obese weight status was associated with not perceiving best friend as a confidant (1.59, 1.11-2.28). No associations were found between weight status and number of close...

  7. Bibliography of Soviet Laser Developments, Number 76, March - April 1985.

    Science.gov (United States)

    1986-06-01

    ABBREVIATIONS (Note: CTC - cover-to-cover translation available) ATPLB Acta physica polonica . Series A AVMEB Avtometriya (CTC) BPPHA Beitraege aus der...CTC) PSSAB Physica status solidi (A). Applied Research (GDR)L PSSBB Physica status solidi (B). Basic Research (GDR) I PZTFD Zhurnal tekhnicheskoy

  8. Bibliography of Soviet Laser Developments, Number 88, March - April 1987.

    Science.gov (United States)

    1988-03-03

    der Physik (Leipzig) ATPLB Acta physica polonica . Series A AVMEB Avtometriya (CTC) BIPED Buletinul Institutului politehnic Gheorghe Gheorghiu-Dej...Problemy fonovogo monitoringa sostoyaniya prirodnoy sredy (abornik, Leningrad) PRTEA Pribory i tekhnika eksperimenta (CTC) PSSAB Physica status solidi (A...Applied Research (GDR) PSSBB Physica status solidi (B). Basic Research (GDR) PZTFD Zhurnal tekhnicheskoy fiziki. Pis’ma (CTC) RAELA Radiotekhnika i

  9. Bibliography of Soviet Laser Developments, Number 83, May - June 1986.

    Science.gov (United States)

    1987-09-01

    ATPLB Acta physica polonica . Series A AVMEB Avtometriya (CTC) BWATA Biuletyn Wojskowej akademii technicznej imeni Jaroslawa Dabrowskiego CISHPMST...elektronowej Politechniki wroclawskiej (Breslau) PRTEA Pribory i tekhnika eksperimenta (CTC) tPSSAB Physica status solidi (A). Applied Research (GDR) PSSBB... Physica status solidi (B). Basic Research (GDR) PZTFD Zhurnal tekhnicheskoy fiziki. Pis’ma (CTC) IRADID Nauchnyye trudy vysshikh uchebnykh zavedeniy

  10. Bibliography of Soviet Laser Developments, Number 79, September - October 1985.

    Science.gov (United States)

    1987-01-01

    hungarica (Budapest) (formerly APAHA) APYCA Acta physica et chemica. Szeged ATPLB Acta physica polonica . Series A AVMEB Avtometriya (CTC) BPBEE...cover translation available) AKZHA Akusticheskiy zhurnal (CTC) APAHA Acta physica acadeniiae scientiarum hungaricae (flow APHUE) APHUE Acta physica ...Pribory i tekhnika eksperimenta (CTC) PSSAB Physica status solidi (A). Applied Research (GDR) PSSBB Physica status solidi (B). Basic Research (GDR

  11. Status Epilepticus and Refractory Status Epilepticus Management

    Science.gov (United States)

    Abend, Nicholas S.; Bearden, David; Helbig, Ingo; McGuire, Jennifer; Narula, Sona; Panzer, Jessica A.; Topjian, Alexis; Dlugos, Dennis J.

    2014-01-01

    Status epilepticus (SE) describes persistent or recurring seizures without a return to baseline mental status, and is a common neurologic emergency. SE can occur in the context of epilepsy or may be symptomatic of a wide range of underlying etiologies. The clinician’s aim is to rapidly institute care that simultaneously stabilizes the patient medically, identifies and manages any precipitant conditions, and terminates seizures. Seizure management involves “emergent” treatment with benzodiazepines followed by “urgent” therapy with other anti-seizure medications. If seizures persist then refractory SE is diagnosed and management options include additional anti-seizure medications or infusions of midazolam or pentobarbital. This paper reviews the management of pediatric SE and RSE. PMID:25727508

  12. Management of status epilepticus.

    Science.gov (United States)

    Pichler, M; Hocker, S

    2017-01-01

    Status epilepticus is a neurologic and medical emergency manifested by prolonged seizure activity or multiple seizures without return to baseline. It is associated with substantial medical cost, morbidity, and mortality. There is a spectrum of severity dependent on the type of seizure, underlying pathology, comorbidities, and appropriate and timely medical management. This chapter discusses the evolving definitions of status epilepticus and multiple patient and clinical factors which influence outcome. The pathophysiology of status epilepticus is reviewed to provide a better understanding of the mechanisms which contribute to status epilepticus, as well as the potential long-term effects. The clinical presentations of different types of status epilepticus in adults are discussed, with emphasis on the hospital course and management of the most dangerous type, generalized convulsive status epilepticus. Strategies for the evaluation and management of status epilepticus are provided based on available evidence from clinical trials and recommendations from the Neurocritical Care Society and the European Federation of Neurological Societies. © 2017 Elsevier B.V. All rights reserved.

  13. STATUS GIZI DAN STATUS KESEHATAN SUKU BADUY

    Directory of Open Access Journals (Sweden)

    Faisal Anwar

    2012-03-01

    Full Text Available 800x600 Normal 0 false false false IN X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Calibri","sans-serif"; mso-bidi-font-family:"Times New Roman";} The objectives of the study were: (1 To analyze the socio-economic and demographic characteristics of Baduy people; (2 To analyze the health status and nutritional status of Baduy people and its influential factors. This research is an explorative and descriptive study on the socio-cultural aspects of food system. The data were collected through a direct interview and discussion with respondents as well as a direct observation at the location of respondents. A sample size of 338 households was drawn from the population. To obtain the data on the cultural aspects, history and  socio aspect of food, in-depth interviews was conducted with 19 key persons. The study was last for 12 months. In Outer Baduy, the factors significantly related to nutritional status are age, number of household size, income, nutritional knowledge, and wife’s ability to read. In Moslem Baduy, only age and income are related to the nutritional status of children. In Moslem Baduy and the Outer Baduy, the correlation between age and W/A or W/H is similar: namely, the higher the age, the lower would the Z-score for the W/A or W/H. The income is significantly correlated to the child nutritional status according to Z-score for W/A with a high correlation coefficient, that is, 0.61. This means that the higher the income, the higher would be the Z-score value for the W/A.  The distribution of adults according to BMI classification in Outer Baduy it shows that 12.7% husbands and 17.6% wives are thin (wasted, while the

  14. Deadline Compliance Status Reports

    Data.gov (United States)

    Department of Housing and Urban Development — These monthly Deadline Compliance Status Reports assist Participating Jurisdictions and HUD Field Offices in monitoring compliance with the 2-year commitment and...

  15. Topical report review status

    International Nuclear Information System (INIS)

    1982-08-01

    A Topical Report Review Status is scheduled to be published semi-annually. The primary purpose of this document is to provide periodic progress reports of on-going topical report reviews, to identify those topical reports for which the Nuclear Regulatory Commission (NRC) staff review has been completed and, to the extent practicable, to provide NRC management with sufficient information regarding the conduct of the topical report program to permit taking whatever actions deemed necessary or appropriate. This document is also intended to be a source of information to NRC Licensing Project Managers and other NRC personnel regarding the status of topical reports which may be referenced in applications for which they have responsibility. This status report is published primarily for internal NRC use in managing the topical report program, but is also used by NRC to advise the industry of report review status

  16. Topical report review status

    International Nuclear Information System (INIS)

    1983-01-01

    A Topical Report Review Status is scheduled to be published semi-annually. The primary purpose of this document is to provide periodic progress reports of on-going topical report reviews, to identify those topical reports for which the Nuclear Regulatory Commission (NRC) staff review has been completed and, to the extent practicable, to provide NRC management with sufficient information regarding the conduct of the topical report program to permit taking whatever actions deemed necessary or appropriate. This document is also intended to be a source of information to NRC Licensing Project Managers and other NRC personnel regarding the status of topical reports which may be referenced in applications for which they have responsibility. This status report is published primarily for internal NRC use in managing the topical report program, but is also used by NRC to advise the industry of report review status

  17. PRESENT STATUS IN INDIA

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. PRESENT STATUS IN INDIA. FIXED LINES – 36 MILLION. MOBILE CONNECTIONS – 14 MILLION. TELEDENSITY APPROXIMATELY 5. INTERNET CONNECTIONS – 5 MILLION. INTERNET USERS NEARLY – 25 MILLION.

  18. NAIP Status Maps Gallery

    Data.gov (United States)

    Farm Service Agency, Department of Agriculture — NAIP Status Maps Gallery. These maps illustrate what aerial imagery collection is planned, whats been collected, when it is available and how it is available. These...

  19. Safety system status monitoring

    International Nuclear Information System (INIS)

    Lewis, J.R.; Morgenstern, M.H.; Rideout, T.H.; Cowley, P.J.

    1984-03-01

    The Pacific Northwest Laboratory has studied the safety aspects of monitoring the preoperational status of safety systems in nuclear power plants. The goals of the study were to assess for the NRC the effectiveness of current monitoring systems and procedures, to develop near-term guidelines for reducing human errors associated with monitoring safety system status, and to recommend a regulatory position on this issue. A review of safety system status monitoring practices indicated that current systems and procedures do not adequately aid control room operators in monitoring safety system status. This is true even of some systems and procedures installed to meet existing regulatory guidelines (Regulatory Guide 1.47). In consequence, this report suggests acceptance criteria for meeting the functional requirements of an adequate system for monitoring safety system status. Also suggested are near-term guidelines that could reduce the likelihood of human errors in specific, high-priority status monitoring tasks. It is recommended that (1) Regulatory Guide 1.47 be revised to address these acceptance criteria, and (2) the revised Regulatory Guide 1.47 be applied to all plants, including those built since the issuance of the original Regulatory Guide

  20. Safety system status monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Lewis, J.R.; Morgenstern, M.H.; Rideout, T.H.; Cowley, P.J.

    1984-03-01

    The Pacific Northwest Laboratory has studied the safety aspects of monitoring the preoperational status of safety systems in nuclear power plants. The goals of the study were to assess for the NRC the effectiveness of current monitoring systems and procedures, to develop near-term guidelines for reducing human errors associated with monitoring safety system status, and to recommend a regulatory position on this issue. A review of safety system status monitoring practices indicated that current systems and procedures do not adequately aid control room operators in monitoring safety system status. This is true even of some systems and procedures installed to meet existing regulatory guidelines (Regulatory Guide 1.47). In consequence, this report suggests acceptance criteria for meeting the functional requirements of an adequate system for monitoring safety system status. Also suggested are near-term guidelines that could reduce the likelihood of human errors in specific, high-priority status monitoring tasks. It is recommended that (1) Regulatory Guide 1.47 be revised to address these acceptance criteria, and (2) the revised Regulatory Guide 1.47 be applied to all plants, including those built since the issuance of the original Regulatory Guide.

  1. Rethinking status dystonicus.

    Science.gov (United States)

    Ruiz-Lopez, Marta; Fasano, Alfonso

    2017-12-01

    Status dystonicus is a movement disorder emergency that has been a source of controversy in terms of terminology, phenomenology, and management since it was first described in 1982. Here we argue that the current use of the term status dystonicus falls well short of the precision needed for either clinical or academic use. We performed a critical review on this topic, describing possible pathophysiological mechanisms and areas of uncertainties. This review also addresses the problems derived by the extreme clinical heterogeneity of this condition, as the lack of an objective criterion useful for the definition, or the fact that status dystonicus may present not only in the context of a known dystonic syndrome. We propose a new possible definition that includes not only dystonia but also other hyperkinetic movements in the wide range of movement disorders that can be seen during an episode. The new definition keeps the term status dystonicus and highlights the fact that this is a medical emergency based on the impairment of bulbar and/or respiratory function requiring hospital admission as the principal feature. Furthermore, the new definition should not consider as necessary unspecific features as patient's condition at baseline, the distribution of dystonia, occurrence of systemic symptoms such as fever or laboratory findings. We hope that this proposal will stimulate the debate on this subject among our peers, further developing a clinical and pathophysiological understanding of status dystonicus. © 2017 International Parkinson and Movement Disorder Society. © 2017 International Parkinson and Movement Disorder Society.

  2. Refractory status epilepticus

    Directory of Open Access Journals (Sweden)

    Sanjay P Singh

    2014-01-01

    Full Text Available Refractory status epilepticus is a potentially life-threatening medical emergency. It requires early diagnosis and treatment. There is a lack of consensus upon its semantic definition of whether it is status epilepticus that continues despite treatment with benzodiazepine and one antiepileptic medication (AED, i.e., Lorazepam + phenytoin. Others regard refractory status epilepticus as failure of benzodiazepine and 2 antiepileptic medications, i.e., Lorazepam + phenytoin + phenobarb. Up to 30% patients in SE fail to respond to two antiepileptic drugs (AEDs and 15% continue to have seizure activity despite use of three drugs. Mechanisms that have made the treatment even more challenging are GABA-R that is internalized during status epilepticus and upregulation of multidrug transporter proteins. All patients of refractory status epilepticus require continuous EEG monitoring. There are three main agents used in the treatment of RSE. These include pentobarbital or thiopental, midazolam and propofol. RSE was shown to result in mortality in 35% cases, 39.13% of patients were left with severe neurological deficits, while another 13% had mild neurological deficits.

  3. Refractory status epilepticus

    Science.gov (United States)

    Singh, Sanjay P; Agarwal, Shubhi; Faulkner, M

    2014-01-01

    Refractory status epilepticus is a potentially life-threatening medical emergency. It requires early diagnosis and treatment. There is a lack of consensus upon its semantic definition of whether it is status epilepticus that continues despite treatment with benzodiazepine and one antiepileptic medication (AED), i.e., Lorazepam + phenytoin. Others regard refractory status epilepticus as failure of benzodiazepine and 2 antiepileptic medications, i.e., Lorazepam + phenytoin + phenobarb. Up to 30% patients in SE fail to respond to two antiepileptic drugs (AEDs) and 15% continue to have seizure activity despite use of three drugs. Mechanisms that have made the treatment even more challenging are GABA-R that is internalized during status epilepticus and upregulation of multidrug transporter proteins. All patients of refractory status epilepticus require continuous EEG monitoring. There are three main agents used in the treatment of RSE. These include pentobarbital or thiopental, midazolam and propofol. RSE was shown to result in mortality in 35% cases, 39.13% of patients were left with severe neurological deficits, while another 13% had mild neurological deficits. PMID:24791086

  4. Status of voluntary restraint

    Energy Technology Data Exchange (ETDEWEB)

    Aarts, W. [SWOKA Institute for Strategic Consumer Behaviour, Leiden (Netherlands)

    2000-05-01

    Do people enjoying a higher status, especially those with a higher education, constrain their consumption more than others? In general, higher status and high levels of consumption go hand in hand. But the greater availability of luxury goods has led to a decline in their exclusivity. Since environmental awareness has increased, a countercurrent may be possible. It is possible that certain high status groups, the environmentally aware trendsetters, can now be distinguished by their voluntary restraint rather than by their conspicuous consumption. This hypothesis formed the basis for a sociological doctoral project at the University of Amsterdam. The research was conducted under the umbrella of the National Research Programme on Global Air Pollution and Climate Change.

  5. Fukushima Daiichi Status Report

    International Nuclear Information System (INIS)

    2012-01-01

    The IAEA issues regular status reports to the public on the current status of the Fukushima Daiichi Nuclear Power Plant, including information on environmental radiation monitoring, the status of workers, and current conditions on-site at the plant. The information cited in this report is compiled from official Japanese sources, including the Ministry of Economy, Trade and Industry (METI), the Nuclear and Industrial Safety Agency (NISA), the Ministry of Education, Culture, Sports, Science and Technology (MEXT), the Ministry of Land, Infrastructure, Transport and Tourism (MLIT), the Ministry of Health, Labour and Welfare (MHLW) and the Ministry of Foreign Affairs (MOFA) through the Japanese Permanent Mission in Vienna and the Cabinet's Office of the Prime Minister. Information is also provided by the Tokyo Electric Power Company (TEPCO), the operator of the Fukushima Daiichi Nuclear Power Plant.

  6. Status Report Jilin University

    Energy Technology Data Exchange (ETDEWEB)

    Dong, Yang; Huo Junde, E-mail: huojd@jlu.edu.cn

    2013-08-15

    Status of mass chain evaluation: Jilin University (JLU) group is responsible for nuclear structure and decay data evaluation of mass chains: A=52, 53, 54, 55, 56, and 63. (1) Status of publication in Nuclear Data Sheets (NDS): 52 - NDS, 106, 773 (2007); 53 - NDS, 110, 2689 (2009); 54 - NDS, 107, 1393 (2006); 55 - NDS, 109, 787 (2008); 56 - NDS, 112, 1513 (2011); 63 - NDS, 92, 147 (2001); ENSDF (2009) (2) Evaluation since last meeting (2011). A=54 in review (since 26-Dec-2012) A=52 evaluating A=63 evaluating. Other activities are briefly presented.

  7. New Service Status Board

    CERN Multimedia

    2013-01-01

    On Monday 14 October, the Service Status Board for GS and IT will change. The new Status Board will be integrated with the CERN Service Portal and with the CERN Service Catalogue.   As of today, the SSB will display “Service Incidents”, “Planned Interventions” and “Service Changes”. References valid from 14 October: CERN SSB at https://cern.ch/ssb Computing SSB (previously IT SSB) at https://cern.ch/itssb   Nicole Cremel, IT and GS Service Management Support

  8. NICMOS status and plans

    Science.gov (United States)

    Thompson, Rodger I.

    1997-01-01

    Near Infrared Camera and Multi-Object Spectrometer (NICMOS) has been in orbit for about 8 months. This is a report on its current status and future plans. Also included are some comments on particular aspects of data analysis concerning dark subtraction, shading, and removal of cosmic rays. At present NICMOS provides excellent images of high scientific content. Most of the observations utilize cameras 1 and 2 which are in excellent focus. Camera 3 is not yet within the range of the focus adjustment mechanism, but its current images are still quite excellent. In this paper we will present the status of various aspects of the NICMOS instrument.

  9. FRIB Cryogenic Plant Status

    Energy Technology Data Exchange (ETDEWEB)

    Dixon, Kelly D. [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Ganni, Venkatarao [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Knudsen, Peter N. [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Casagranda, Fabio [Michigan State Univ., East Lansing, MI (United States)

    2015-12-01

    After practical changes were approved to the initial conceptual design of the cryogenic system for MSU FRIB and an agreement was made with JLab in 2012 to lead the design effort of the cryogenic plant, many activities are in place leading toward a cool-down of the linacs prior to 2018. This is mostly due to using similar equipment used at CHLII for the 12 GeV upgrade at JLab and an aggressive schedule maintained by the MSU Conventional Facilities department. Reported here is an updated status of the cryogenic plant, including the equipment procurement status, plant layout, facility equipment and project schedule.

  10. HESYRL control system status

    International Nuclear Information System (INIS)

    Yao Chihyuan

    1992-01-01

    HESYRL synchrotron radiation storage ring was completed in 1989 and has been in commissioning since then. Now it has met its design specification and is ready for synchrotron light experiments. Control system of the project was completed in 1989 and some modifications were made during commissioning. This paper describes its present configuration, status and upgrading plan. (author)

  11. Experimental status QCD

    International Nuclear Information System (INIS)

    Radyushkin, A.V.; Slepchenko, L.A.

    1983-01-01

    Analysis of experimental status of quantum chromodynamics (QCD) has been carried out. A short introduction into QCD is given. QCD sum rules are considered. Jets in e + e - annihilation and inclusive processes of lepton-hadron and hadron-hadron scattering are considered. Effect of QCD corrections to perturbation theory on quark count is analyzed

  12. Somalia: Country Status Report.

    Science.gov (United States)

    McFerren, Margaret

    A survey of the status of language usage in Somalia begins with an overview of the usage patterns of Somali, the official language, and three languages previously used officially: English, Italian, and Arabic. The cultural context that for many years has supported the usage of a single native language for communication and administration is also…

  13. Behavior, Expectations and Status

    Science.gov (United States)

    Webster, Jr, Murray; Rashotte, Lisa Slattery

    2010-01-01

    We predict effects of behavior patterns and status on performance expectations and group inequality using an integrated theory developed by Fisek, Berger and Norman (1991). We next test those predictions using new experimental techniques we developed to control behavior patterns as independent variables. In a 10-condition experiment, predictions…

  14. VERITAS: status c.2005

    International Nuclear Information System (INIS)

    Weekes, T. C.; Atkins, R. W.; Badran, H. M.; Blaylock, G.; Bond, I. H.; Boyle, P. J.; Bradbury, S. M.; Buckley, J. H.; Bryum, K. L.; Carter-Lewis, D. A.; Celik, O.; Chow, Y. C. K.; Cogan, P.; Cui, W.; Daniel, M. K.; Calle Perez, I. de la; Dowdall, C.; Dowkontt, P.; Duke, C.; Ergin, T.

    2006-01-01

    VERITAS (Very Energetic Radiation Imaging Telescope Array System), is one of a new generation of TeV gamma-ray observatories. The current status of its construction is described here. The first two telescopes and cameras have been completed and meet the design specifications; the full array of four telescopes could be operational by the end of 2006

  15. Status of TRISTAN operation

    International Nuclear Information System (INIS)

    Satoh, Kotaro

    1990-01-01

    The present status of the TRISTAN operation is summarized mainly after the installation of superconducting cavities in the 1988 summer shutdown. The paper describes the initial experience of the superconducting cavity operation, the colliding operation at 30.4 GeV and the beam injection. Future improvement is also reported. (author)

  16. Nuclear power status 1999

    International Nuclear Information System (INIS)

    2000-01-01

    The document gives statistical information on nuclear power plants status in the world in 1999, including the number of reactors in operation or under construction, the electricity supplied by nuclear power reactors and the respective percentage of electricity produced by nuclear energy in 1999, and the total operating experience to 31 December 1999, by country

  17. Algeria: Country Status Report.

    Science.gov (United States)

    McFerren, Margaret

    A survey of the status of language usage in Algeria begins with an overview of the usage patterns of Arabic, the Berber languages, and French. The country's return to Arabic as its official language after independence from France in 1962 is discussed along with the resultant language planning, issues of language of instruction at the elementary,…

  18. Glueballs: a status report

    International Nuclear Information System (INIS)

    Scharre, D.L.

    1982-01-01

    It is expected from quantum chromodynamics (QCD) that glueballs, bound states which contain gluons but no valence quarks, should exist. To date, no conclusive evidence for glueballs has been presented. After a brief review of the expected properties and experimental signatures of glueballs the status of some glueball candidate states are discussed

  19. Status, Numbers and Influence

    Science.gov (United States)

    Melamed, David; Savage, Scott V.

    2013-01-01

    We develop a theoretical model of social influence in n-person groups. We argue that disagreement between group members introduces uncertainty into the social situation, and this uncertainty motivates people to use status characteristics to evaluate the merits of a particular opinion. Our model takes the numerical distribution of opinions and the…

  20. Super Refractory Status Epilepticus

    African Journals Online (AJOL)

    user

    et al did retrospective cohort study from 1 January st. 1994 to 31 March 1998 at Presbyterian Medical. Centre in Columbia, to determine the frequency, risk factors and impact on the outcome of RSE. They found out that 69% of seizures recurred after. Key Words: Super refractory status epilepticus, Zambia. Medical Journal of ...

  1. Status of Tristan

    International Nuclear Information System (INIS)

    Horikoshi, G.; Kimura, Y.

    1987-01-01

    After the five years construction period, the TRISTAN electron-positron beam collider was commissioned successfully in November 1986. With three detectors installed at three out of four beam collision areas in the ring, colliding beam experiments have begun in December 1986. The current status of the TRISTAN accelerator operation is presented along with a brief description on the accelerator sub-systems

  2. COMPASS Status Report 2010

    CERN Document Server

    COMPASS Collaboration

    2010-01-01

    This report gives an overview of the setup and the performance of the COMPASS experiment during the 2009 hadron beam run and describes the preparation and startup of the 2010 muon beam run with the polarised target. The status of analysis is presented both for the hadron and muon data with emphasis on the 2008/2009 hadron data.

  3. Fusion safety status report

    International Nuclear Information System (INIS)

    1986-10-01

    This report includes information on a) tritium handling and safety; b) activation product generation and release; c) lithium safety; d) superconducting magnet safety; e) operational safety and shielding; f) environmental impact; g) recycling, decommissioning and waste management; and h) accident analysis. Recommendations for high priority research and development are presented, as well as the current status in each area

  4. Angola: Country Status Report.

    Science.gov (United States)

    Bruhn, Thea C.

    A survey of the status of language usage in Angola begins with an overview of the usage and distribution of Portuguese as the official language, and the four most significant native languages and dialects spoken there: Umbundu, Kimbundu, Kikongo, and Lunda-Chokwe. The introduction of Spanish through Cuban trainers, teachers, and military advisors…

  5. NASA Armstrong Status

    Science.gov (United States)

    Jacobson, Steven R.

    2014-01-01

    Armstrong (formerly Dryden) Flight Research Center continues it's legacy of exciting work in the area of dynamics and control of advanced vehicle concepts. This status presentation highlights the research and technology development that Armstrong's Control and Dynamics branch is performing in the areas of Control of Flexible Structures and Automated Cooperative Trajectories.

  6. Assessment of Mental Status.

    Science.gov (United States)

    Finney, Glen R; Minagar, Alireza; Heilman, Kenneth M

    2016-02-01

    Assessing the mental status of patients with a neurobehavioral disorder is a critical element in the diagnosis and treatment of these patients. This assessment should always be performed after the patient's history it taken and a general physical as well as a neurologic examination is completed. The mental status examination commences with observing the patient's appearance and level of consciousness. The examiner should also pay attention to patient's social behavior, emotional state and mood. There are 3 major means of assessing a patient's mental status. One type attempts to determine if the patient is demented and the severity of the dementia as it pertains to their ability to perform activities of daily living as well as instrumental activities. A second type of assessment utilizes what may be termed as "screening tests" or "omnibus tests". These brief tests are performed independent of the patient's history and examination. The two most frequently used screening tests are the Mini-Mental Status Examination (MMSE) and the Montreal Cognitive Assessment (MoCA). The third means of assessing a patient's mental status is by using specific neuropsychological tests that focus on specific domains of cognition, such as frontal executive functions, attention, episodic verbal and visuospatial memory, declarative knowledge such as language (speech, reading and writing) and arithmetical, as well as visuospatial and perceptual abilities. These neurobehavioral, neuropsychiatric and neuropsychological assessments of patients with a cognitive decline and behavioral abnormalities should often be accompanied by laboratory tests, and neuroimaging that can help determine the underlying pathologic process so that effective therapeutic and management approaches can be provided. Copyright © 2016 Elsevier Inc. All rights reserved.

  7. Status of memory loss.

    LENUS (Irish Health Repository)

    Iyer, Parameswaran Mahadeva

    2012-01-01

    A 72-year-old woman presented with first onset of seizure with no prior history of cognitive dysfunction. EEG revealed focal non-convulsive status epilepticus. MRI brain showed a left temporal non-enhancing lesion. Temporal pole biopsy showed acute neuronal necrosis and astrocyte hyperplasia together with extensive amyloid plaques and neurofibrillary tangles. Perivascular oligodendroglial hyperplasia was present. Postmortem examination revealed extensive plaque and tangle disease. Perivascular oligodendroglial hyperplasia was limited to the left temporal area. The presence of focal perivascular oligodendroglial hyperplasia in the left temporal cortex, combined with extensive plaque and tangle disease may have contributed to the focal status epilepticus in this patient. Although the presence of focal perivascular oligodendroglial hyperplasia has been reported in cases of temporal lobe epilepsy, it has not been reported as a cause of seizure in patients with Alzheimer\\'s disease previously. Further studies for clinical-pathologic correlation would be required to confirm this hypothesis.

  8. Status of fusion maintenance

    International Nuclear Information System (INIS)

    Fuller, G.M.

    1984-01-01

    Effective maintenance will be an essential ingredient in determining fusion system productivity. This level of productivity will result only after close attention is paid to the entire system as an entity and appropriate integration of the elements is made. The status of fusion maintenance is reviewed in the context of the entire system. While there are many challenging developmental tasks ahead in fusion maintenance, the required technologies are available in several high-technology industries, including nuclear fission

  9. ISIS status report

    International Nuclear Information System (INIS)

    Finney, J.L.; Gray, D.A.

    1989-01-01

    The authors review the progress on ISIS, the pulsed neutron source at the Rutherford-Appleton Laboratory, since the last ICANS meeting. The machine is now running regularly at 100 μA at 750 MeV, and delivering neutrons for an increasing UK and international neutron scattering program. The current status of the operating and development instruments is summarized, and some examples given of recent science. 3 refs., 11 figs., 3 tabs

  10. Status of MARS Code

    Energy Technology Data Exchange (ETDEWEB)

    N.V. Mokhov

    2003-04-09

    Status and recent developments of the MARS 14 Monte Carlo code system for simulation of hadronic and electromagnetic cascades in shielding, accelerator and detector components in the energy range from a fraction of an electronvolt up to 100 TeV are described. these include physics models both in strong and electromagnetic interaction sectors, variance reduction techniques, residual dose, geometry, tracking, histograming. MAD-MARS Beam Line Build and Graphical-User Interface.

  11. Battery waste management status

    International Nuclear Information System (INIS)

    Barnett, B.M.; Sabatini, J.C.; Wolsky, S.

    1993-01-01

    The paper consists of a series of slides used in the conference presentation. The topics outlined in the slides are: an overview of battery waste management; waste management of lead acid batteries; lead acid recycling; typical legislation for battery waste; regulatory status in European countries; mercury use in cells; recent trends in Hg and Cd use; impact of batteries to air quality at MSW incinerators; impact of electric vehicles; new battery technologies; and unresolved issues

  12. FASTBUS software status

    International Nuclear Information System (INIS)

    Gustavson, D.B.

    1980-10-01

    Computer software will be needed in addition to the mechanical, electrical, protocol and timing specifications of the FASTBUS, in order to facilitate the use of this flexible new multiprocessor and multisegment data acquisition and processing system. Software considerations have been important in the FASTBUS design, but standard subroutines and recommended algorithms will be needed as the FASTBUS comes into use. This paper summarizes current FASTBUS software projects, goals and status

  13. ATLAS construction status

    International Nuclear Information System (INIS)

    Jenni, P.

    2006-01-01

    The ATLAS detector is being constructed at the LHC, in view of a data-taking startup in 2007. This report concentrates on the progress and the technical challenges of the detector construction, and summarizes the status of the work as of August 2004. The project is on track to allow the highly motivated ATLAS Collaboration to enter into a new exploratory domain of high-energy physics in 2007. (author)

  14. Status of gluonium searches

    International Nuclear Information System (INIS)

    Heusch, C.A.; California Univ., Santa Cruz, CA

    1991-01-01

    Quantum chromodynamics predicts the existence of quarkless mesons. The search for these hadrons has been ingenious and persevering. A review is presented of the current status of research that considers all model-dependent theoretical prejudice when searching for specific states. Early hints for candidate states have been investigated in the light of recent data, mostly from the Mark III Collaboration, in radiative charmonium decay. No 'smoking-gun' candidate stands out. (R.P.) 25 refs., 20 figs., 2 tabs

  15. Automated Status Notification System

    Science.gov (United States)

    2005-01-01

    NASA Lewis Research Center's Automated Status Notification System (ASNS) was born out of need. To prevent "hacker attacks," Lewis' telephone system needed to monitor communications activities 24 hr a day, 7 days a week. With decreasing staff resources, this continuous monitoring had to be automated. By utilizing existing communications hardware, a UNIX workstation, and NAWK (a pattern scanning and processing language), we implemented a continuous monitoring system.

  16. The status of GALLEX

    International Nuclear Information System (INIS)

    Cribier, M.

    1990-01-01

    The present status of the Gallium Solar Neutrino Experiment performed by the GALLEX Collaboration in the Gran Sasso Underground Laboratory is described. The implementation phase of this experiment is now completed, the whole gallium is at hand and data taking starts now. After a short introduction and an outline of the basic experimental procedure, details will be given on different parts of the experiment and on some background. 14 refs., 2 figs

  17. Women Status and their Discrimination

    OpenAIRE

    PEŠKOVÁ, Pavlína

    2008-01-01

    My work deal with women status and their discrimination. Chapter one contains women status in different historical periods and development of their status to bigger equal with men. There is also written about present feminist trends. Chapter two is about women discrimination. There is about women´ job discrimination, job segregation according to gender and inequality in payment. There is also written about women status at home and unequal duties at home among family mates. Chapter three is ab...

  18. Sibling Status Effects: Adult Expectations.

    Science.gov (United States)

    Baskett, Linda Musun

    1985-01-01

    This study attempted to determine what expectations or beliefs adults might hold about a child based on his or her sibling status alone. Ratings on 50 adjective pairs for each of three sibling status types, only, oldest, and youngest child, were assessed in relation to adult expectations, birth order, and parental status of rater. (Author/DST)

  19. Status of safeguards instrumentation

    International Nuclear Information System (INIS)

    Higinbotham, W.A.

    The International Atomic Energy Agency is performing safeguards at some nuclear power reactors, 50 bulk processing facilities, and 170 research facilities. Its verification activities require the use of instruments to measure nuclear materials and of surveillance instruments to maintain continuity of knowledge of the locations of nuclear materials. Instruments that are in use and under development to measure weight, volume, concentration, and isotopic composition of nuclear materials, and the major surveillance instruments, are described in connection with their uses at representative nuclear facilities. The current status of safeguards instrumentation and the needs for future development are discussed

  20. Model Validation Status Review

    International Nuclear Information System (INIS)

    E.L. Hardin

    2001-01-01

    The primary objective for the Model Validation Status Review was to perform a one-time evaluation of model validation associated with the analysis/model reports (AMRs) containing model input to total-system performance assessment (TSPA) for the Yucca Mountain site recommendation (SR). This review was performed in response to Corrective Action Request BSC-01-C-01 (Clark 2001, Krisha 2001) pursuant to Quality Assurance review findings of an adverse trend in model validation deficiency. The review findings in this report provide the following information which defines the extent of model validation deficiency and the corrective action needed: (1) AMRs that contain or support models are identified, and conversely, for each model the supporting documentation is identified. (2) The use for each model is determined based on whether the output is used directly for TSPA-SR, or for screening (exclusion) of features, events, and processes (FEPs), and the nature of the model output. (3) Two approaches are used to evaluate the extent to which the validation for each model is compliant with AP-3.10Q (Analyses and Models). The approaches differ in regard to whether model validation is achieved within individual AMRs as originally intended, or whether model validation could be readily achieved by incorporating information from other sources. (4) Recommendations are presented for changes to the AMRs, and additional model development activities or data collection, that will remedy model validation review findings, in support of licensing activities. The Model Validation Status Review emphasized those AMRs that support TSPA-SR (CRWMS M and O 2000bl and 2000bm). A series of workshops and teleconferences was held to discuss and integrate the review findings. The review encompassed 125 AMRs (Table 1) plus certain other supporting documents and data needed to assess model validity. The AMRs were grouped in 21 model areas representing the modeling of processes affecting the natural and

  1. The status of GALLEX

    Energy Technology Data Exchange (ETDEWEB)

    Kirsten, T.; Anselmann, P.; Breitenbach, M.; Hampel, W.; Heusser, G.; Kiko, J.; Kirsten, T.; Lenzing, A.; Pernicka, E.; Plaga, R.; Povh, B.; Schlosser, C.; Voelk, H.; Wink, R.; Wojcik, M. (Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany, F.R.)); Bellotti, E. (Laboratori Nazionali del Gran Sasso (Italy)); Ammon, R. v.; Balata, M.; Ebert, K.; Fritsch, T.; Hellriegel, K.; Henrich, E.; Stieglitz, L.; Weyrich, F. (Kernforschungszentrum Karlsruhe GmbH (Germany, F.R.)); Cremonesi, O.; Fiorini, E.; Ragazzi, S.; Zanotti, L. (Milan Univ. (Italy). Dipt. di Fisica); Feilitzsch, F. v.; Moessbauer, R.; Schanda, U. (Technische Univ. Muenchen, Garching (Germany, F.R.). Fakultaet fuer Physik); Berthomieu, G.; Schatzmann, E. (Nice Univ., 06 (France). Observatoire); Carmi, I.; Dostrovsky, I. (Weizmann Inst. of Science, Rehovoth (Israel)); D' Angelo, S.; Bacci, C.; Belli, P.; Bernabei, R.; Paoluzi, L. (Rome-2 Univ. (Italy)); Cribier, M.; Dupont, G.; Gosset, L.; Pichard, B.; Rich, J.; Spiro; GALLEX Collaboration

    1991-04-01

    A radiochemical Gallium-Solar-Neutrino Detector has been set up at the Gran Sasso Underground Laboratory. All major installations are implemented and the target, 53,5 m{sup 3} of galliumchloride solution containing 30.3 tons of gallium, has been brought underground after removing cosmogenic Ge-isotopes through nitrogen purge. This final implementation status and the achieved parameters characterizing the experiment are described in this report. Full scale performance tests and optimalization of the operating conditions of the extraction system are presently under way. (orig.).

  2. Status of APE projects

    CERN Document Server

    Alfieri, R; Onofri, E; Bartoloni, A; Battista, C; Cabibbo, Nicola; Cosimi, M; Lonardo, A; Michelotti, A; Proietti, B; Rapuano, F; Rossetti, D; Sacco, G; Tassa, S; Torelli, M; Vicini, P; Pène, O; Errico, W; Magazzù, G; Sartori, L; Schiiano, F; Tripiccione, R; De Riso, P; Petronzio, Roberto; Destri, C; Frezzotti, R; Marchesini, G; Gensch, Ulrich; Jansen, K; Kretzschmann, A; Leich, H; Paschedag, N; Pleiter, D; Schwendicke, U; Simma, H; Sommer, Rainer; Sulanke, K; Wegner, P; Fucci, A; Martin, B; Pech, J; Panizzi, E; Petricola, A

    2001-01-01

    This talk is divided in two parts. In the first part, we will summarize the status of the APEmille project that will be completed by the end of the year. We will then devote the rest of the talk to the description of a new project for a multi-TeraFlop machine, ape NEXT. The interested reader will find a much more detailed discussion of all the items touched upon here in the full proposal of the project that will shortly appear on hep-lat. (9 refs).

  3. Teleradiology - current status

    International Nuclear Information System (INIS)

    Baltadjiev, D.; Charakchiev

    2000-01-01

    Tele-radiology is a term becoming increasingly popular in the medical literature. Nevertheless, terminological definitions in this particular field are still rather vague. The scope of applications extend from simple image presenting via analogue telephone lines to transmission of 3-D medical images through a satellite. It is a matter of standards highly differing in terms of data transmission rates, safety, technical demands on the systems and the like. In this article new information technologies, technical aspects, as well as some major applications of tele-radiology are discussed. The current status of tele-medicine/tele-radiology in this country is likewise briefly outlined

  4. Status epilepticus in scleromyxedema

    Institute of Scientific and Technical Information of China (English)

    Soifa Markoula; Soifa Zouroudi; Soitrios Giannopoulos; Kimon Tsoukanelis; Ananstasia Zikou; Athanassios P Kyritsis

    2016-01-01

    Scleromyxedema is a rare dermatologic disorder, characterized by erythematous or yelowish lichenoid waxy papules. Neurological manifestations are rare but wel-recognized. A 51-year-old woman, diagnosed with scleromyxedema, was admitted to the hospital with status epilepticus, caused by brain lesions, as disclosed in a brain magnetic resonance imaging (MRI). The patient was treated with anticonvulsants and corticosteroids and gradualy recovered fuly. A complete remission of the lesions was shown in a folow-up brain MRI. In cases with scleromyxedema and the presence of neurological manifestations, we need to pay attention to central nervous system involvement, especialy when combined with brain MRI lesions, and treat the patient appropriately.

  5. 1998 status report

    International Nuclear Information System (INIS)

    1998-01-01

    Since its creation in 1945, the activities of Cea have been centered on the study and development of the pacific use of nuclear energy and on assuring the credibility of nuclear deterrent. This status report presents the research programs led by Cea in 1998. The main topics are: the designing of reactor cores, fuel cycle, nuclear safety, radiation protection, the activities for defense, high technologies for industry, biology and fundamental sciences. The quality of research work is assured by an independent and regular assessment of the scientific activities. (A.C.)

  6. Model Validation Status Review

    Energy Technology Data Exchange (ETDEWEB)

    E.L. Hardin

    2001-11-28

    The primary objective for the Model Validation Status Review was to perform a one-time evaluation of model validation associated with the analysis/model reports (AMRs) containing model input to total-system performance assessment (TSPA) for the Yucca Mountain site recommendation (SR). This review was performed in response to Corrective Action Request BSC-01-C-01 (Clark 2001, Krisha 2001) pursuant to Quality Assurance review findings of an adverse trend in model validation deficiency. The review findings in this report provide the following information which defines the extent of model validation deficiency and the corrective action needed: (1) AMRs that contain or support models are identified, and conversely, for each model the supporting documentation is identified. (2) The use for each model is determined based on whether the output is used directly for TSPA-SR, or for screening (exclusion) of features, events, and processes (FEPs), and the nature of the model output. (3) Two approaches are used to evaluate the extent to which the validation for each model is compliant with AP-3.10Q (Analyses and Models). The approaches differ in regard to whether model validation is achieved within individual AMRs as originally intended, or whether model validation could be readily achieved by incorporating information from other sources. (4) Recommendations are presented for changes to the AMRs, and additional model development activities or data collection, that will remedy model validation review findings, in support of licensing activities. The Model Validation Status Review emphasized those AMRs that support TSPA-SR (CRWMS M&O 2000bl and 2000bm). A series of workshops and teleconferences was held to discuss and integrate the review findings. The review encompassed 125 AMRs (Table 1) plus certain other supporting documents and data needed to assess model validity. The AMRs were grouped in 21 model areas representing the modeling of processes affecting the natural and

  7. Integrated process status overview

    International Nuclear Information System (INIS)

    Gertman, D.I.; Gaudio, P. Jr.

    1986-01-01

    This report summarizes findings to date with the IPSO, a large plant status overview currently under development at the OECD Halden Reactor Project. As part of a joint Halden and Combustion Engineering project, the overview is being tested in part to determine whether the large screen overview concept being entertained for use in the nuclear power plant (NPP) industry will facilitate operator performance. To this end an interactive simulation technique was used to establish a proof-of-principle test for the IPSO. Process control, operations, and human factors experts at Halden participated in the test and evaluation

  8. NESTOR: A status report

    CERN Document Server

    Anassontzis, E G; Barone, M; Foudas, C; Grammatikakis, G; Katsanevas, S; Kourkoumelis, C; Manousakis-Katsikakis, A; Resvanis, L K; Siotis, I; Sotiriou, S A; Voulgaris, G; Minkowski, P; Grieder, P K F; Ball, A E; Bottai, S; Cartacci, A M; Monteleoni, B; Naumov, Vadim A; Trasatti, L; Fahrun, E; Keusen, U; Koske, P; Rathlev, J; Schmidt, N P; Voight, G; Bezrukov, Leonid B; Butkevich, A V; Dedenko, L G; Karaevsky, S K; Mironovich, A A; Zakharov, L M; Zheleznykh, I M; Zhukov, V A; Demidova, T A; Deineko, A O; Eremeev, A P; Paka, V T; Permyakov, A A; Platonov, M N; Rukol, V Kh; Sheremet, N A; Surin, N M; Albul, V I; Ledenev, V V

    2000-01-01

    NESTOR is an underwater neutrino astrophysics laboratory to be located in the international waters of the southwest of Greece. The first phase of this experiment is the construction and deployment of one hexagonal tower consisting of 168 optical modules, with effective are of 20000m2 for E ⩾ TeV neutrinos. Over the past few years detailed studies of the site have been carried out while many tests have been performed. The current status of the preparation of the experiment and the future plans will be presented.

  9. Reactor gamma spectrometry: status

    International Nuclear Information System (INIS)

    Gold, R.; Kaiser, B.J.

    1979-01-01

    Current work is described for Compton Recoil Gamma-Ray Spectrometry including developments in experimental technique as well as recent reactor spectrometry measurements. The current status of the method is described concerning gamma spectromoetry probe design and response characteristics. Emphasis is given to gamma spectrometry work in US LWR and BR programs. Gamma spectrometry in BR environments are outlined by focussing on start-up plans for the Fast Test Reactor (FTR). Gamma spectrometry results are presented for a LWR pressure vessel mockup in the Poolside Critical Assembly (PCA) at Oak Ridge National Laboratory

  10. Relationships between Psychosocial Resilience and Physical Health Status of Western Australian Urban Aboriginal Youth

    Science.gov (United States)

    Hopkins, Katrina D.; Shepherd, Carrington C. J.; Taylor, Catherine L.; Zubrick, Stephen R.

    2015-01-01

    Background Psychosocial processes are implicated as mediators of racial/ethnic health disparities via dysregulation of physiological responses to stress. Our aim was to investigate the extent to which factors previously documented as buffering the impact of high-risk family environments on Aboriginal youths’ psychosocial functioning were similarly beneficial for their physical health status. Method and Results We examined the relationship between psychosocial resilience and physical health of urban Aboriginal youth (12–17 years, n = 677) drawn from a representative survey of Western Australian Aboriginal children and their families. A composite variable of psychosocial resilient status, derived by cross-classifying youth by high/low family risk exposure and normal/abnormal psychosocial functioning, resulted in four groups- Resilient, Less Resilient, Expected Good and Vulnerable. Separate logistic regression modeling for high and low risk exposed youth revealed that Resilient youth were significantly more likely to have lower self-reported asthma symptoms (OR 3.48, padaptation that impact on the physical health of Aboriginal youth. The results support the posited biological pathways between chronic stress and physical health, and identify the protective role of social connections impacting not only psychosocial function but also physical health. Using a resilience framework may identify potent protective factors otherwise undetected in aggregated analyses, offering important insights to augment general public health prevention strategies. PMID:26716829

  11. Determination of HIV Status in African Adults With Discordant HIV Rapid Tests.

    Science.gov (United States)

    Fogel, Jessica M; Piwowar-Manning, Estelle; Donohue, Kelsey; Cummings, Vanessa; Marzinke, Mark A; Clarke, William; Breaud, Autumn; Fiamma, Agnès; Donnell, Deborah; Kulich, Michal; Mbwambo, Jessie K K; Richter, Linda; Gray, Glenda; Sweat, Michael; Coates, Thomas J; Eshleman, Susan H

    2015-08-01

    In resource-limited settings, HIV infection is often diagnosed using 2 rapid tests. If the results are discordant, a third tie-breaker test is often used to determine HIV status. This study characterized samples with discordant rapid tests and compared different testing strategies for determining HIV status in these cases. Samples were previously collected from 173 African adults in a population-based survey who had discordant rapid test results. Samples were classified as HIV positive or HIV negative using a rigorous testing algorithm that included two fourth-generation tests, a discriminatory test, and 2 HIV RNA tests. Tie-breaker tests were evaluated, including rapid tests (1 performed in-country), a third-generation enzyme immunoassay, and two fourth-generation tests. Selected samples were further characterized using additional assays. Twenty-nine samples (16.8%) were classified as HIV positive and 24 of those samples (82.8%) had undetectable HIV RNA. Antiretroviral drugs were detected in 1 sample. Sensitivity was 8.3%-43% for the rapid tests; 24.1% for the third-generation enzyme immunoassay; 95.8% and 96.6% for the fourth-generation tests. Specificity was lower for the fourth-generation tests than the other tests. Accuracy ranged from 79.5% to 91.3%. In this population-based survey, most HIV-infected adults with discordant rapid tests were virally suppressed without antiretroviral drugs. Use of individual assays as tie-breaker tests was not a reliable method for determining HIV status in these individuals. More extensive testing algorithms that use a fourth-generation screening test with a discriminatory test and HIV RNA test are preferable for determining HIV status in these cases.

  12. Status of Standardization Projects

    Science.gov (United States)

    1991-06-30

    MCA GL G4 913 914 914 A GL SA 50 SS N D 8915 TOTAL- 6. DELINQUENT- 0. STATUS CODES: A- 5, G- 1. Y- 0, Z- 0 8920 0539 MIL R 35084A RICE INSTANT ENRICHED...44171GL CARROTS GLA POW GL H5 904 914 914 A N D 8940 A693 MIL N 44178GL NOODLES PARMESAN AND ROMA GL H5 904 914 914 A N D 8940 A694 MIL P 44181GL PIE...20184 COFFEE INSTANT GL B4 A 893 903 913 A GL SA 50 SS U B 8955 0062 MIL T 3527D I NOT 1 TEA INSTANT GL H5 912 921 921 A GL SA 50 SS N 8955 TOTAL- 2

  13. Belle status and prospects

    International Nuclear Information System (INIS)

    Hara, Takanori

    2003-01-01

    We review the current status and the future perspectives of the Belle experiment and KEKB asymmetric e + e - collider. Thanks to many efforts of Belle collaborators and KEKB accelerator staffs, we could accumulate a 41.8 fb -1 data by the end of 2001 (more than 80 fb -1 data by the end of summer, 2002), also the KEKB recorded the highest peak luminosity (7.35 x 10 33 cm -2 s -1 ) in the world. Furthermore, the Super KEKB project is being proposed not only to extract the CP violation parameters and moduluses of the CKM matrix with high accuracy, but also to search for B rare decays and explore beyond the Standard Model

  14. Status of French reactors

    Energy Technology Data Exchange (ETDEWEB)

    Ballagny, A. [Commissariat a l`Energie Atomique, Saclay (France)

    1997-08-01

    The status of French reactors is reviewed. The ORPHEE and RHF reactors can not be operated with a LEU fuel which would be limited to 4.8 g U/cm{sup 3}. The OSIRIS reactor has already been converted to LEU. It will use U{sub 3}Si{sub 2} as soon as its present stock of UO{sub 2} fuel is used up, at the end of 1994. The decision to close down the SILOE reactor in the near future is not propitious for the start of a conversion process. The REX 2000 reactor, which is expected to be commissioned in 2005, will use LEU (except if the fast neutrons core option is selected). Concerning the end of the HEU fuel cycle, the best option is reprocessing followed by conversion of the reprocessed uranium to LEU.

  15. Mars Drilling Status

    Science.gov (United States)

    Mandell, Humboldt, C., Jr.

    2002-01-01

    This slide presentation reviews the current status of work to explore Mars beneath the surface of planet. One of the objective of this work is to enable further exploration of Mars by humans. One of the requirements for this is to find water on Mars. The presences of water is critical for Human Exploration and a permanent presence on Mars. If water is present beneath the surface it is the best chance of finding life on Mars. The presentation includes a timeline showing the robotic missions, those that have already been on Mars, and planned missions, an explanation of why do we want to drill on Mars, and some of the challenges, Also include are reviews of a missions that would drill 200 and 4,000 to 6,000 meters into the Martian bedrock, and a overview description of the drill. There is a view of some places where we have hopes of finding water.

  16. Status of legislation

    International Nuclear Information System (INIS)

    Warner, C.

    1982-01-01

    The status of the House legislation, the major differences between the House and Senate legislation and a preview of what is likely to take place during the lame duck session in December are presented. The House legislation provides: long-term program leading toward permanent disposal of nuclear waste; an interim program for storage and for expansion of storage space for spent fuel; provides an R and D component through what is called a test and evaluation facility; an alternative long-term storage program based on a proposal to be completed by the Department of Energy on what's called Monitored Retrievable Storage; full upfront financing of the program through user fees based on contracts between the government and the users of the nuclear waste disposal services

  17. The status of molecules

    International Nuclear Information System (INIS)

    Barnes, T.; Oak Ridge National Lab., TN; Tennessee Univ., Knoxville, TN

    1994-06-01

    This report summarizes the experimental and theoretical status of hadronic molecules, which are weakly-bound states of two or more hadrons. We begin with a brief history of the subject and discuss a few good candidates, and then abstract some signatures for molecules which may be of interest in the classification of possible molecule states. Next we argue that a more general understanding of 2 → 2 hadron-hadron scattering amplitudes will be crucial for molecule searches, and discuss some of our recent work in this area. We conclude with a discussion of a few more recent molecule candidates (notably the f o (1710)) which are not well established as molecules but satisfy some of the expected signatures. (Author)

  18. LIGO: Status and plans

    International Nuclear Information System (INIS)

    Barish, B.C.

    2001-01-01

    One of the most important consequences of the Theory of General Relativity is the concept of gravitational waves. As we enter the new millennium, a new generation of detectors sensitive enough to directly detect such waves will become operational. Detectable events could originate from a variety of catastrophic events in the distant universe, such as the gravitational collapse of stars or the coalescence of compact binary systems. In this talk, I review the detection technique of suspended mass interferometry, including the status and plans for the Laser Interferometry Gravitational-wave Observatory (LIGO). I also discuss the astrophysical sources of gravitational waves and the preparations for data analysis to search for signals of gravitational waves. (author)

  19. ARAC status report: 1985

    International Nuclear Information System (INIS)

    Dickerson, M.H.; Gudiksen, P.H.; Sullivan, T.J.; Greenly, G.D.

    1985-05-01

    The Atmospheric Release Advisory Capability is a real-time emergency-response service available to federal and state agencies for providing estimates of the environmental consequences of accidental releases of radioactivity into the atmosphere. This includes the estimation of radiation doses to nearby population centers and the levels and extent of surface contamination. The service is currently being expanded to support the emergency response plans at approximately 50 Department of Defense and Department of Energy facilities. This expansion consists of the installation of enhanced computational and data communications and processing systems, development of terrain and geographic data bases, improvements in modeling capabilities, as well as increased staff housing facilities. This report summarizes the current status of ARAC and the requirements to receive the service

  20. Status of the SLC

    International Nuclear Information System (INIS)

    Moffeit, K.C.

    1987-01-01

    The status and research possibilities of the Stanford Linear Collider (SLC) are reviewed. The physics program concentrates on production of Z 0 's and their decay. The SLC systems include a new injector and booster, two damping rings to provide the small beam emittance, a new positron source, the existing LINAC structure upgraded for higher energy and better beam control, beam transport arcs, a final focus section, and experimental halls are detectors. Energy spectrometers with an accuracy of ± 50 MeV/c 2 for pulse-to-pulse center of mass energy measurement are to be installed. Longitudinal polarized electrons are expected, and will allow more precise tests of the standard model

  1. Quasat - European status report

    International Nuclear Information System (INIS)

    Schilizzi, R.T.

    1987-01-01

    The scientific goals, design, and current development status of Quasat are reviewed. Quasat is a proposed 15-m orbiting radio telescope intended to serve as the space leg of an astronomical VLBI network comprising the existing large arrays in Europe, the U.S., the USSR, and Australia. The planned 63-deg-inclination 5700 x 12,500-km elliptical orbit is optimized for high-resolution imaging of quasar and radio-galaxy nuclei at cm wavelengths with the U.S. and European ground arrays. A drawing of the ESA inflatable-antenna concept, a diagram of the space/ground system, and tables listing additional observing targets and the predicted angular and spatial resolutions of a Quasat-based array at different wavelengths are included

  2. Status of CSNS project

    International Nuclear Information System (INIS)

    Zhang, J.; Fu, S.N.; Chen, H.S.

    2015-01-01

    The China Spallation Neutron Source (CSNS) accelerator is designed to accelerate proton beam pulses to 1.6 GeV at 25 Hz repetition rate, striking a solid metal target to produce spallation neutrons. The accelerator provides a beam power of 100 kW on the target in the first phase and then 500 kW in the second phase by increasing the average beam intensity 5 times while raising the linac output energy. The project construction has been formally launched in 2011 and it is planned to complete the project in March 2018. It is one of the high intensity proton accelerator projects in the world and it imposes a great challenge to Chinese accelerator community. This presentation will cover the status and challenges of the CSNS project. (author)

  3. COHERENT Experiment: current status

    International Nuclear Information System (INIS)

    Akimov, D; Belov, V; Bolozdynya, A; Burenkov, A; Albert, J B; Del Valle Coello, M; D’Onofrio, M; Awe, C; Barbeau, P S; Cervantes, M; Becker, B; Cabrera-Palmer, B; Collar, J I; Cooper, R J; Cooper, R L; Cuesta, C; Detwiler, J; Eberhardt, A; Dean, D; Dolgolenko, A G

    2017-01-01

    The COHERENT Collaboration is realizing a long term neutrino physics research program. The main goals of the program are to detect and study elastic neutrino-nucleus scattering (CEνNS). This process is predicted by Standard Model but it has never been observed experimentally because of the very low energy of the recoil nucleus. COHERENT is using different detector technologies: CsI[Na] and NaI scintillator crystals, a single-phase liquid Ar and a Ge detectors. The placement of all the detector setups is in the basement of the Spallation Neutron Source (SNS) at Oak Ridge National Laboratory (ORNL). The current status of the COHERENT experimental program is presented. (paper)

  4. Status of French reactors

    International Nuclear Information System (INIS)

    Ballagny, A.

    1997-01-01

    The status of French reactors is reviewed. The ORPHEE and RHF reactors can not be operated with a LEU fuel which would be limited to 4.8 g U/cm 3 . The OSIRIS reactor has already been converted to LEU. It will use U 3 Si 2 as soon as its present stock of UO 2 fuel is used up, at the end of 1994. The decision to close down the SILOE reactor in the near future is not propitious for the start of a conversion process. The REX 2000 reactor, which is expected to be commissioned in 2005, will use LEU (except if the fast neutrons core option is selected). Concerning the end of the HEU fuel cycle, the best option is reprocessing followed by conversion of the reprocessed uranium to LEU

  5. Updates in Refractory Status Epilepticus

    Science.gov (United States)

    Mahulikar, Advait; Suchdev, Kushak; Shah, Aashit

    2018-01-01

    Refractory status epilepticus is defined as persistent seizures despite appropriate use of two intravenous medications, one of which is a benzodiazepine. It can be seen in up to 40% of cases of status epilepticus with an acute symptomatic etiology as the most likely cause. New-onset refractory status epilepticus (NORSE) is a recently coined term for refractory status epilepticus where no apparent cause is found after initial testing. A large proportion of NORSE cases are eventually found to have an autoimmune etiology needing immunomodulatory treatment. Management of refractory status epilepticus involves treatment of an underlying etiology in addition to intravenous anesthetics and antiepileptic drugs. Alternative treatment options including diet therapies, electroconvulsive therapy, and surgical resection in case of a focal lesion should be considered. Short-term and long-term outcomes tend to be poor with significant morbidity and mortality with only one-third of patients reaching baseline neurological status. PMID:29854452

  6. Occult microscopic endometriosis: undetectable by laparoscopy in normal peritoneum.

    Science.gov (United States)

    Khan, Khaleque Newaz; Fujishita, Akira; Kitajima, Michio; Hiraki, Koichi; Nakashima, Masahiro; Masuzaki, Hideaki

    2014-03-01

    Is there any occurrence of hidden (occult) endometriotic lesions in normal peritoneum of women with and without visible endometriosis? We detected a slightly higher occurrence of occult microscopic endometriosis (OME) in normal peritoneum of women with visible endometriosis than in control women. Based on a small number of cases, the concept of invisible microscopic endometriosis in visually normal peritoneum has been reported for more than a decade but there is controversy regarding their tissue activity and clinical significance. This case-controlled research study was conducted with prospectively collected normal peritoneal samples from 151 women with and 62 women without visible endometriosis. Normal peritoneal biopsy specimens from different pelvic sites of were collected during laparoscopy. A histological search of all peritoneal biopsy specimens for the detection of invisible endometriosis was done by immunoreaction to Ber-EP4 (epithelial cell marker), CD10 (stromal cell marker) and Calretinin (mesothelial cell marker). Tissue expression of estrogen/progesterone receptors (ER/PR) and cell proliferation marker, Ki-67, was performed by immunohistochemistry to identify tissue activity. Three different patterns of OME were detected based on (I) the presence of typical gland/stroma, (II) reactive hyperplastic change of endometrioid epithelial cells with surrounding stroma and (III) single-layered epithelium-lined cystic lesions with surrounding stroma. A higher tendency toward the occurrence of OME was found in women with visible endometriosis (15.2%, 23/151) compared with control women (6.4%, 4/62) (P = 0.06, χ(2) test). The epithelial cells and/or stromal cells of OME lesions were immunoreactive to Ber-EP4 and CD10 but not reactive to Calretinin. ER and PR expression was observed in all patterns of OME lesions. Ki-67 index was significantly higher in pattern I/II OME lesions than in pattern III OME lesions (Pendometriosis due to the presence of adhesions in the pelvis. We re-confirmed a decade long old concept of invisible (occult) endometriosis in visually normal peritoneum of women with visible endometriosis. The existence of a variable amount of tissue activity in these occult lesions may contribute to the recurrence/occurrence of endometriosis or persistence/recurrence of pain manifestation in women even after successful ablation or excision of visible lesions by laparoscopy. This work was supported in part by Grants-in-aid for Scientific Research from the Japan Society for the Promotion of Science. There is no conflict of interest related to this study. Not applicable.

  7. Finding undetected protein associations in cell signaling by belief propagation.

    Science.gov (United States)

    Bailly-Bechet, M; Borgs, C; Braunstein, A; Chayes, J; Dagkessamanskaia, A; François, J-M; Zecchina, R

    2011-01-11

    External information propagates in the cell mainly through signaling cascades and transcriptional activation, allowing it to react to a wide spectrum of environmental changes. High-throughput experiments identify numerous molecular components of such cascades that may, however, interact through unknown partners. Some of them may be detected using data coming from the integration of a protein-protein interaction network and mRNA expression profiles. This inference problem can be mapped onto the problem of finding appropriate optimal connected subgraphs of a network defined by these datasets. The optimization procedure turns out to be computationally intractable in general. Here we present a new distributed algorithm for this task, inspired from statistical physics, and apply this scheme to alpha factor and drug perturbations data in yeast. We identify the role of the COS8 protein, a member of a gene family of previously unknown function, and validate the results by genetic experiments. The algorithm we present is specially suited for very large datasets, can run in parallel, and can be adapted to other problems in systems biology. On renowned benchmarks it outperforms other algorithms in the field.

  8. Oesophageal intubation can be undetected by auscultation of the chest

    DEFF Research Database (Denmark)

    Andersen, K H; Schultz-Lebahn, T

    1994-01-01

    Prompt detection of oesophageal intubation is a primary concern in anaesthetic practice. This blind, randomised study evaluates three widely used tests of intubation. Forty patients had both their trachea and oesophagus intubated, each patient was studied twice. Auscultation of the epigastrium......, right and left axilla is more reliable than auscultation of the chest, and the anaesthetist's feeling when he squeezes the bag. P = 0.001 and P = 0.048, respectively. The tests were carried out after gastric distension with gas had occurred. We conclude that auscultation of epigastrium, right and left...

  9. LSB steganography with improved embedding efficiency and undetectability

    OpenAIRE

    Khalind, Omed; Aziz, Benjamin Yowell Yousif

    2015-01-01

    In this paper, we propose a new method of non-adapt ive LSB steganography in still images to improve the embedding efficiency from 2 to 8/3 rand om bits per one embedding change even for the embedding rate of 1 bit per pixel. The method t akes 2-bits of the secret message at a time and compares them to the LSBs of the two chosen pix el values for embedding, it always assumes a single mismatch between the two and uses the seco nd LSB o...

  10. A Steganographic Embedding Undetectable by JPEG Compatibility Steganalysis

    Science.gov (United States)

    2002-01-01

    itd.nrl.navy.mil Abstract. Steganography and steganalysis of digital images is a cat- and-mouse game. In recent work, Fridrich, Goljan and Du introduced a method...proposed embedding method. 1 Introduction Steganography and steganalysis of digital images is a cat-and-mouse game. Ever since Kurak and McHugh’s seminal...paper on LSB embeddings in images [10], various researchers have published work on either increasing the payload, im- proving the resistance to

  11. Transmission of Mycobacterium tuberculosis Undetected by Tuberculin Skin Testing

    Czech Academy of Sciences Publication Activity Database

    Anderson, S. T.; Williams, A. J.; Brown, J. R.; Newton, S. M.; Šimšová, Marcela; Nicol, M. P.; Šebo, Peter; Levin, M.; Wilkinson, R. J.; Wilkinson, K. A.

    2006-01-01

    Roč. 173, - (2006), s. 1038-1042 ISSN 1073-449X R&D Projects: GA AV ČR IAA5020406 Institutional research plan: CEZ:AV0Z50200510 Keywords : adenylate cyclase * diagnostic tests and procedures * mycobacterium tuberculosis Subject RIV: EE - Microbiology, Virology Impact factor: 9.091, year: 2006

  12. Temporal lobe deficits in murderers: EEG findings undetected by PET.

    Science.gov (United States)

    Gatzke-Kopp, L M; Raine, A; Buchsbaum, M; LaCasse, L

    2001-01-01

    This study evaluates electroencephalography (EEG) and positron emission tomography (PET) in the same subjects. Fourteen murderers were assessed by using both PET (while they were performing the continuous performance task) and EEG during a resting state. EEG revealed significant increases in slow-wave activity in the temporal, but not frontal, lobe in murderers, in contrast to prior PET findings that showed reduced prefrontal, but not temporal, glucose metabolism. Results suggest that resting EEG shows empirical utility distinct from PET activation findings.

  13. Bartonella henselae endocarditis in Laos - 'the unsought will go undetected'.

    Directory of Open Access Journals (Sweden)

    Sayaphet Rattanavong

    2014-12-01

    Full Text Available Both endocarditis and Bartonella infections are neglected public health problems, especially in rural Asia. Bartonella endocarditis has been described from wealthier countries in Asia, Japan, Korea, Thailand and India but there are no reports from poorer countries, such as the Lao PDR (Laos, probably because people have neglected to look.We conducted a retrospective (2006-2012, and subsequent prospective study (2012-2013, at Mahosot Hospital, Vientiane, Laos, through liaison between the microbiology laboratory and the wards. Patients aged >1 year admitted with definite or possible endocarditis according to modified Duke criteria were included. In view of the strong suspicion of infective endocarditis, acute and convalescent sera from 30 patients with culture negative endocarditis were tested for antibodies to Brucella melitensis, Mycoplasma pneumoniae, Bartonella quintana, B. henselae, Coxiella burnetii and Legionella pneumophila. Western blot analysis using Bartonella species antigens enabled us to describe the first two Lao patients with known Bartonella henselae endocarditis.We argue that it is likely that Bartonella endocarditis is neglected and more widespread than appreciated, as there are few laboratories in Asia able to make the diagnosis. Considering the high prevalence of rheumatic heart disease in Asia, there is remarkably little evidence on the bacterial etiology of endocarditis. Most evidence is derived from wealthy countries and investigation of the aetiology and optimal management of endocarditis in low income countries has been neglected. Interest in Bartonella as neglected pathogens is emerging, and improved methods for the rapid diagnosis of Bartonella endocarditis are needed, as it is likely that proven Bartonella endocarditis can be treated with simpler and less expensive regimens than "conventional" endocarditis and multicenter trials to optimize treatment are required. More understanding is needed on the risk factors for Bartonella endocarditis and the importance of vectors and vector control.

  14. Biosimilar drugs: Current status.

    Science.gov (United States)

    Kumar, Rajiv; Singh, Jagjit

    2014-07-01

    Biologic products are being developed over the past three decades. The expiry of patent protection for many biological medicines has led to the development of biosimilars in UK or follow on biologics in USA. This article reviews the literature on biosimilar drugs that covers the therapeutic status and regulatory guidelines. Appraisal of published articles from peer reviewed journals for English language publications, search from PubMed, and guidelines from European Medicines Agency, US Food Drug Administration (FDA) and India were used to identify data for review. Literature suggest that biosimilars are similar biological products, i.e., comparable but not identical to the reference product, are not generic version of innovator product and do not ensure therapeutic equivalence. Biosimilars present more challenges than conventional generics and marketing approval is also more complicated. To improve access, US Congress passed the Biologics Price Competition and Innovation act 2009 and US FDA allowed "abbreviated pathway" for their approval. U.S law has defined new standards and terms and EMA scientific guidelines have also set detailed approval standards. India being one of the most preferred manufacturing destinations of biosimilars, there is a need for stringent safety and regulatory guidelines. The New India Guidelines "Draft Guidelines on Similar Biologics were announced in June 2012, by Department of Biotechnology at Boston bio and available online.

  15. Status of fusion technology

    International Nuclear Information System (INIS)

    Mohan, Ashok

    1978-01-01

    The current status of fusion technology is surveyed. Limited reserves of fossil fuel and dangers of proliferation from nuclear reactors have brought into focus the need to develop an optional energy source. Fusion is being looked upon as an optional energy source which is free from environmental hazards unlike fossil fuels and nuclear reactors. Investments in R and D of fusion energy have increased rapidly in USA, Japan, USSR and European countries. Out of the various fusion fuels known, a mixture of D and T is widely chosen. The main problem in fusion technology is the confinement of plasma for a time sufficient to start the fusion reaction. This can be done magnetically or inertially. The three approaches to magnetic confinement are : (1) tokamak, (2) mirror and (3) pinch. Inertial confinement makes use of lasers or electron beams or ion beams. Both the methods of confinement i.e. magnetic and inertial have problems which are identified and their nature is discussed. (M.G.B.)

  16. Nanometals - Status and perspective

    International Nuclear Information System (INIS)

    Faester, S.; Hansen, N.; Huang, X.; Juul Jensen, D.; Ralph, B.

    2012-01-01

    Nanometals and nanotechnology have over the years been covered in papers, books and conferences - also in many Risoe International Symposia, where the 30th in 2009 dealt solely with nanostructured metals. Since then, rapid progress has been made in synthesis, characterization and modeling, and it is timely to discuss status and perspective also with a view on applications in an international forum such as the Risoe Symposium. Both keynote and contributed papers address important current problems illustrating global research and development in this field. Examples are the development of new synthesis techniques followed by characterization and modeling of microstructures both in 2D and 3D now starting to bridge the micrometer scales. The vital area of mechanical behavior is addressed by the development of new testing techniques and a broad effort to characterize and model mechanical properties of metals strengthened by dislocations and twins. This research has now led to new understanding of both strengthening mechanisms and strengh structure relationships based on experiments in combination with analytical and numerical modeling. The holistic approach to research on nanometals demonstrated by these proceedings can guide both scientists and technologists in their future work also with the aim of introducing into society this new group of advanced materials. Such an effort is important, as science and technology today is significantly affected by politics of governments and international institutions, and therefore a new initiative in the pressent is to include a discussion of research and development in the area of nanometals i USA, China and Japan. (Author)

  17. Nanometals - Status and perspective

    Energy Technology Data Exchange (ETDEWEB)

    Faester, S.; Hansen, N.; Huang, X.; Juul Jensen, D.; Ralph, B. (eds.)

    2012-11-01

    Nanometals and nanotechnology have over the years been covered in papers, books and conferences - also in many Risoe International Symposia, where the 30th in 2009 dealt solely with nanostructured metals. Since then, rapid progress has been made in synthesis, characterization and modeling, and it is timely to discuss status and perspective also with a view on applications in an international forum such as the Risoe Symposium. Both keynote and contributed papers address important current problems illustrating global research and development in this field. Examples are the development of new synthesis techniques followed by characterization and modeling of microstructures both in 2D and 3D now starting to bridge the micrometer scales. The vital area of mechanical behavior is addressed by the development of new testing techniques and a broad effort to characterize and model mechanical properties of metals strengthened by dislocations and twins. This research has now led to new understanding of both strengthening mechanisms and strengh structure relationships based on experiments in combination with analytical and numerical modeling. The holistic approach to research on nanometals demonstrated by these proceedings can guide both scientists and technologists in their future work also with the aim of introducing into society this new group of advanced materials. Such an effort is important, as science and technology today is significantly affected by politics of governments and international institutions, and therefore a new initiative in the pressent is to include a discussion of research and development in the area of nanometals i USA, China and Japan. (Author)

  18. Status of load management

    Energy Technology Data Exchange (ETDEWEB)

    Juchymenko, A

    1983-08-01

    A summary is presented of the status of load management, defined as any activity by an electric utility to affect the size and characteristics of its load. Load management is currently viewed by electric utilities as an important tool for marketing electricity in a competitive fuel situation. A major aim of the National Energy Program is to reduce Canada's dependence on oil by 1990 to 10% of the energy used by all markets. As a result, electricity may play a greater role in the supply of primary energy. Research in load management has been directed mostly towards the residential market, especially direct control of domestic hot water heaters and air conditioners. Studies conducted in Canada and the U.S. to determine user's receptiveness to direct control of loads and thermal energy storage systems indicate that these load management techniques are in most cases not acceptable to customers, who prefer voluntary reduction in demand. The potential exists in the industrial market to use load management to assist in electrifying many of the fossil fuel-fired processes at competitive energy prices. Some of the more important applications include an industrial heat pump to heat liquids to 120{degree}C, induction heating for melting and heat treating of metals, and mechanical vapor recompression equipment to produce proces steam. 21 refs., 2 figs., 2 tabs.

  19. TESLA Test Facility. Status

    International Nuclear Information System (INIS)

    Aune, B.

    1996-01-01

    The TESLA Test Facility (TTF), under construction at DESY by an international collaboration, is an R and D test bed for the superconducting option for future linear e+/e-colliders. It consists of an infrastructure to process and test the cavities and of a 500 MeV linac. The infrastructure has been installed and is fully operational. It includes a complex of clean rooms, an ultra-clean water plant, a chemical etching installation and an ultra-high vacuum furnace. The linac will consist of four cryo-modules, each containing eight 1 meter long nine-cell cavities operated at 1.3 GHz. The base accelerating field is 15 MV/m. A first injector will deliver a low charge per bunch beam, with the full average current (8 mA in pulses of 800 μs). A more powerful injector based on RF gun technology will ultimately deliver a beam with high charge and low emittance to allow measurements necessary to qualify the TESLA option and to demonstrate the possibility of operating a free electron laser based on the Self-Amplified-Spontaneous-Emission principle. Overview and status of the facility will be given. Plans for the future use of the linac are presented. (R.P.)

  20. CTC Sentinel. Volume 8, Issue 6, June 2015

    Science.gov (United States)

    2015-06-01

    growing gap between adversary use of technology and our own technology and laws—the “going dark ” phenomenon1 as you have called it. Is this a...threats to the country as threats to the country’s more developed coastal region, home to most of Tunisia’s economically vital tourism industry. This...operation in tourism , trade and security,” Agence Tunis Afrique Presse, May 17, 2015. “Tunisian people grateful to Algeria for its solidarity

  1. CTC Sentinel. Volume 7, Issue 6, June 2014

    Science.gov (United States)

    2014-06-01

    The f ighters were very animated and emotional when answering this question. J ihad, for them, is an ult imate, purifying expression of faith...aspects of life… it gives meaning to the human life. I have devoted my entire life for jihad. All my bodily parts are wounded. I am only looking up to...of Colombia – People’s Army,” Mapping Militant Organizations, Stanford Uni- versity, August 13, 2012. unclear whether the central command of the

  2. CTC Sentinel. Volume 9, Issue 5, May 2016

    Science.gov (United States)

    2016-05-01

    funds through microfinance techniques within the European Union and transferring the proceeds to the Islamic State. With the very recent death of...presence on the al-Qa`ida-affiliated Ansar al-Mujahideen English language forum and other similar al-Qa`ida-linked jihadist forums like Qital Tube and

  3. CTC Sentinel. Volume 5, Issue 1, January 2012

    Science.gov (United States)

    2012-01-01

    New York Times, March 18, 2010. 25 Howard La Franchi , “A Look Inside a Giant Drug Cartel,” Christian Science Monitor, December 6, 1999. 26 David...the rule of law. Lack of access to social services and higher education, growing social inequality, civilian casualties caused by international...oppressive rule by the American- backed warlords, your brothers stood up and established peace and justice in this land.9 Since then, Hammami’s public

  4. CTC Sentinel. Volume 2, Issue 5, May 2009

    Science.gov (United States)

    2009-05-01

    in Gaza and criticism of Arab leaders, including Egyptian President Hosni Mubarak, Hizb Allah leader Hassan Nasrallah, and Saudi Interior Minister...alleged al-Qa`ida media coordinator formerly affiliated with Egyptian Jama`a al-Islamiyya. Saudi documents charge him with holding a senior...community in February and March 2009, after a handful of Shi`a were manhandled by religious police during a pilgrimage to the tombs of their imams at the

  5. CTC Sentinel. Volume 3, Issue 3, March 2010

    Science.gov (United States)

    2010-03-01

    stories of the Prophet Muhammad’s companions . Yet his lectures also veer into the topics of prototypical Salafist discourse. Beginning around 2004...Pakistan is Said to Pursue Role in U.S.- Afghan Talks,” New York Times, February 9, 2010. 22 Willi Germund, “Pakistan lässt Taliban- Chef mARCH 2010 . VoL...cite the precedent of the famous commander and companion of the Prophet Muhammad, Khalid bin 22 Abid Mehsud, July 2008. 23 Ishaq Mehsud, June

  6. CTC Sentinel. Volume 5, Issue 4, April 2012

    Science.gov (United States)

    2012-04-01

    Nigerian journalists have speculated that the group now exists on a franchise basis, and that some attacks on Christians, murderous as they are...March 7, 2012 (IRAQ): A car bomb exploded outside a restaurant in a Shi`a area of Tal Afar, Ninawa Province. As people gathered to help the wounded...at the time of the strike. – AP, March 30 March 31, 2012 (KENYA): An assailant threw a hand grenade into a crowded restaurant in Mombasa, injuring

  7. CTC Sentinel. Volume 4, Issue 9, September 2011

    Science.gov (United States)

    2011-09-01

    Sahel: Al-Qa’ida’s Franchise or Freelance?” Middle East Institute, August 2011. 11 Djaffar Tamani, “Retour de la Peur en Kabylie,” El- Watan, April 19...blasts at one restaurant , as many as 10 Uighur men shot and stabbed people indiscriminately, including the firefighters who came to the rescue...encountered online to attempt a suicide attack in an Exeter chain restaurant ; diners were only saved by the fact that the bomb blew up in his face

  8. CTC Sentinel. Volume 3, Issue 2, February 2010

    Science.gov (United States)

    2010-02-01

    difficulty of creating a Lebanese franchise , it is likely that al-Qa`ida has switched its strategy and gone underground.2 Clandestine terrorist...Of course, no leader belonging to al-Qa`ida central or to any of its franchises in the Middle East has made a pub- lic statement detailing a...Reilly was only prevented by his own incompetence when his bomb failed to detonate properly in the middle of a restaurant in Exeter in May 2008

  9. CTC Sentinel. Volume 4 Number 1, January 2011

    Science.gov (United States)

    2011-01-01

    of a man wearing a sketchy billboard sign for “London restaurant ” with a red khaffiyeh wrapped around his face that seemed to be the only...attention has been firmly fixed on al-Qa`ida’s latest regional franchise based in Yemen—a focus that has only increased in intensity following a...cannot faci l i tate the violence of i ts franchises , as well as other jihadist actors, to launch attacks against the United States. In short

  10. CTC Sentinel. Volume 3, Issue 7, July 2010

    Science.gov (United States)

    2010-07-01

    as peculiar, but it is a visible manifestation of the depth of divide between the Sunni and Shi`a jihads.” 3 Since 2003, al-Qa`ida’s franchise in...Kampala, on July 11, 2010.1 The attacks— targeting a rugby club and an Ethiopian restaurant in a neighborhood popular with expatriates as people watched... franchises ” such as the Ghazi Force only if they prove worthy of attention. Thus, newly emerging groups have to prove themselves to the TTP high

  11. CTC Sentinel. Volume 8, Issue 7, July 2015

    Science.gov (United States)

    2015-07-01

    document from Phillip Morris in 1981 captured this mentality. “Today’s teenager is tomorrow’s potential regular customer.”13 Targeting America’s youth...Implications and Related Demographic Trends,” Philip Morris Companies, Inc., March 31, 1981, Bates No 1000390803/0855, pg. 1. 14 Ibid., Farrelly, et al...Commander, USSOCOM “The Future of Counterterrorism” Tuesday , 21 April 2015 session 4 partnerships & building partner capacity Given the

  12. CTC Sentinel. Volume 3, Issue 9, September 2010

    Science.gov (United States)

    2010-09-01

    reported as far west as the Maldives and as far south as the Mozambique Channel, tending to “ migrate ” as weather conditions around the HoA deteriorate...specialists, Copenhagen, Denmark, March 2010. 18 “Pirates Seize Singapore Cargo Ship in the Gulf of Aden,” BBC, June 28, 2010; Tristan McConnell...designation of Kashmiri appears to portray him as the overall commander of HuJI. 53 An additional case of interest is that of Bangladeshi - born British

  13. CTC Sentinel. Volume 7, Issue 4, January 2014

    Science.gov (United States)

    2014-01-01

    new threat, the “biohacker.” “Biohacking” is not necessarily malicious and could be as innocent as a beer enthusiast altering yeast to create a...turn operated by the Egyptian government.7 The canal generates around $5 billion per year for Egypt and is an important source of foreign currency...toll charges at Panama and the deployment of 18,000 20-foot equivalent unit (TEU) vessels, further increasing the importance of the Suez route to

  14. CTC Sentinel. Volume 7, Issue 2, February 2014

    Science.gov (United States)

    2014-02-01

    types of threats it poses, and its future prospects. It finds that al-Shabab is a franchise with distinct components, the fastest growing of...ranks.5 Although not formally an al- Qa`ida franchise during this time, al- Shabab benefited from public relations support and advisers from al-Qa`ida.6...damaged its reputation among Somalis by blocking international food aid from entering most of its areas of control, denying that a famine existed

  15. CTC Sentinel. Volume 8, Issue 4, April 2015

    Science.gov (United States)

    2015-04-01

    already moved some of the girls kidnapped in Chibok, Nigeria, across the border into Chad.30 Boko Haram’s first attack on Chadian soil occurred...Afghanistan, Pakistan, Iraq, Nigeria, Colombia , and numerous other at- risk countries. He is a 1969 graduate of the U.S. Military Academy, and was...After admission, Pak files 26/11 charge sheet”, Times Now TV, 18 July, 2009; Also See, “Part of 26/11 plot hatched on our soil , admits Pak,” Mid Day

  16. CTC Sentinel. Volume 2, Issue 12, December 2009

    Science.gov (United States)

    2009-12-01

    Daniel Pearl in Karachi.13 The network’s members rented two basement apartments in Toronto as a Working Group (CTWG), George C. Marshall European...Dash, Regionalism in South Asia: Negotiating Cooperation, Institu- tional Structures (London: Routledge, 2008). DeCembeR 2009 . VoL 2 . IssUE 12...ida in the Arabian Peninsula called on militants to bomb airports and trains in Western countries, explaining that explosives can easily be

  17. CTC Sentinel. Volume 7, Issue 11. November/December 2014

    Science.gov (United States)

    2014-12-01

    4 Author interviews in Ankara, Turkey with party ac- tivists and members of the former Democratic Society Party, currently the Peace and Democracy ...This process, commonly referred to as its ‘Lebanonization’ or infitah (opening), is reflective of Hizb Allah’s formal entry into participatory and

  18. CTC Sentinel. Volume 7, Issue 8, August 2014

    Science.gov (United States)

    2014-08-01

    UK citizens. When they [the foreign and local fighters] come to the café they tell me to turn off the music (which I do), and they watch videos...Antares music event known as a Baile Funk party hosted by the Red Command on a Friday night, the gangsters even danced holding their r i f les...finalist for the Los Angeles Times’ Festival of Books and The Orwell Prize. 42 Personal interview, CORE commander Rodrigo Ol- iveira, Rio de

  19. CTC Sentinel. Volume 5, Issue 10, October 2012

    Science.gov (United States)

    2012-10-01

    cohesion. As an organization, Los Zetas was feared but held its shape. As a decentralized network, Los Zetas presents a new criminal typology where...Shabab, the al-Qa`ida- linked Somali militant group that has abducted foreign aid workers and tourists in Kenya. Since its October intervention in...Grenades, Gunfire: Three Dead in Kenyan Tourist City,” CNN, October 17, 2012. posing as locals and counting on outdated profiling by Kenyan security

  20. CTC Sentinel. Volume 3, Number 11-12, November 2010

    Science.gov (United States)

    2010-11-01

    discrete ethnic and geographic entities, Umarov’s imagined community lacks meaningful cohesion. These deficiencies inform the fragmentation now evident...with more than 20 local commanders flocking to the troika’s banner.20 15 “Amir IK Dokku Abu Usman obyavil o svoem preem- nike . Im stal Amir

  1. The Optimization of a Microfluidic CTC Filtering Chip by Simulation

    Directory of Open Access Journals (Sweden)

    Huan Li

    2017-03-01

    Full Text Available The detection and separation of circulating tumor cells (CTCs are crucial in early cancer diagnosis and cancer prognosis. Filtration through a thin film is one of the size and deformability based separation methods, which can isolate rare CTCs from the peripheral blood of cancer patients regardless of their heterogeneity. In this paper, volume of fluid (VOF multiphase flow models are employed to clarify the cells’ filtering processes. The cells may deform significantly when they enter a channel constriction, which will induce cell membrane stress and damage if the area strain is larger than the critical value. Therefore, the cellular damage criterion characterized by membrane area strain is presented in our model, i.e., the lysis limit of the lipid bilayer is taken as the critical area strain. Under this criterion, we discover that the microfilters with slit-shaped pores do less damage to cells than those with circular pores. The influence of contact angle between the microfilters and blood cells on cellular injury is also discussed. Moreover, the optimal film thickness and flux in our simulations are obtained as 0.5 μm and 0.375 mm/s, respectively. These findings will provide constructive guidance for the improvement of next generation microfilters with higher throughput and less cellular damage.

  2. CTC Sentinel. Volume 2, Issue 6, June 2009

    Science.gov (United States)

    2009-06-01

    establish a leather - tanning works in Mumbai’s Kurla area.37 Like Sheikh, though, Shahbandri dropped out of high school and became a full-time SIMI...173 Cr.P.C.) in the Court of Additional Chief Metropoli- tan Magistrate, 37th Court, Esplanade, Mumbai,” Mum- bai Police Headquarters, February 25...attempt. – AFP, May 13 May 13, 2009 (PHILIPPINES): A roadside bomb targeted the governor of Sulu Province, Abdusakur Tan . The governor survived the

  3. CTC Sentinel. Volume 6, Issue 5, May 2013

    Science.gov (United States)

    2013-05-01

    TTP militants have moved from FATA and the KP to Karachi. Security analysts attribute this migration to Pakistan’s military operations in the...April 7, 2013. 47 Urdu-speaking Muslims migrated to Pakistan when the country became independent from the British in 1947, and they largely...contractual, “fee-for-service” basis. Notable groups include Los Negros, Los Gueritos, Los Pelones, Los Números, Los Chachos, Los Lobos, Los Sinaloa

  4. CTC Sentinel. Volume 5, Issue 2, February 2012

    Science.gov (United States)

    2012-02-01

    Los Zetas grew independent of the Gulf Cartel, the organization was at a disadvantage because it did not have contacts in Colombia or other...Terrorism in North Africa and the Sahel: Al-Qaida’s Franchise or Freelance,” Middle East Institute, August 201; “Islamist Terrorism in the Sahel

  5. CTC Sentinel. Volume 8, Issue 9, September 2015

    Science.gov (United States)

    2015-09-01

    weeks later when another Islamic State–affiliated group in Libya beheaded 21 Egyptian Coptic Christians. It is even possible that we could see one or...information and analysis architecture that serves the counterterrorism enterprise all across the country, not just at the federal level but with state...July 9, 2015. 9 Mohamed Fadel Fahmy, “ Egyptian comrades remember reported leader of al Qaeda,” CNN, May 20, 2011. 10 Aaron Zelin, “As-Sahab Media

  6. CTC Sentinel. Volume 4, Issue 3, March 2011

    Science.gov (United States)

    2011-03-01

    these programs. When economic measures failed to quell the discontent, President Salih turned to political concessions on February 2. In a speech to... Alexa (a website that measures traffic), google.com. eg is the second most popular website in Egypt. Google. com is the fourth. It is important to...benefit to the Haqqanis: it provides them with worldwide recognition and credibility, and likely helps with funding and recruitment. The network’s

  7. CTC Sentinel. Volume 7, Issue 9, September 2014

    Science.gov (United States)

    2014-09-01

    to cottage in the summertime, I loved to fish, I wanted to go hunting, I liked outdoors, I liked sports …life in Canada was good. I had money, I...Almani. 34 Soraya Sarhaddi Nelson, “‘Jihad Tourism ’: From Ger- many to the Syrian Battlefield,” National Public Radio, December 22, 2013. Assessing

  8. CTC Sentinel. Volume 7, Issue 10, October 2014

    Science.gov (United States)

    2014-10-01

    In- filtration,” thenewage.za, July 12, 2014. 3 The journalist mentioned was Ahmed Salkida. See Em- manuel Elebeke, “Boko Haram has 50,000 Members...August 6, 2014; Em- manuel Uzodinma, “Boko Haram Abducts 15 Persons in Cameroon Village, Kills Three,” DailyPost, August 19, 2014; “Cameroon Kills 27...While 28 Arlyn dela Cruz , “More Filipino Militants Fight in Iraq,” Philippine Daily Inquirer, August 9, 2014. 29 “Filipino Muslim Fighters Not

  9. CTC Sentinel. Volume 9, Issue 11, November/December 2016

    Science.gov (United States)

    2016-12-01

    in par- ticular in Libya, Syria, and Iraq, a depressing pattern established itself where the United States killed terrorist leaders while they...West, was swift to recognize the potential of YouTube , a vid- eo-sharing platform established in 2005. A 2009 British govern- ment analysis found 1,910...videos of al-Awlaki on YouTube , one of which had been viewed 164,420 times.12 As before, the new tech- nology often complemented older means of

  10. CTC Sentinel. Volume 4, Issue 10, October 2011

    Science.gov (United States)

    2011-10-01

    continued to inflect his discourse well up to the 9/11 attacks. Soundscapes Leading Home The polyphony of voices in the collection presents the single...percent of the collection. These “ soundscapes ” include conversations in the cramped quarters of moving taxi cabs, classroom lectures and student- teacher

  11. CTC Sentinel. Volume 7, Issue 4, April 2014

    Science.gov (United States)

    2014-04-01

    managed to integrate into local communities over time.” 3 activities were supplemented by trade and farming .10 They speak their own language...they wanted to buy a goat from the locals, they paid the owner double his asking price.32 They bought themselves goodwill, friendship and networks...indigenous campesinos (peasant farmers), but included many large farm owners and businessmen.18 They also had to become a more potent armed force

  12. CTC Sentinel. Volume 10, Issue 2. February 2017

    Science.gov (United States)

    2017-02-01

    Bashan, Lia Harris, Cathy Morris, and Taylor Auerbach, “Parramatta shooting: Multiple shots fired outside police HQ on Charles Street,” Daily...occasionally providing different numbers. The issue is also clouded by the fact that many fighters were accompanied by their wives and children when making

  13. CTC Sentinel. Volume 6, Issue 7, July 2013

    Science.gov (United States)

    2013-07-01

    Times, January 16, 2012. 38 “‘I Want to Harm Israel,’ Saudi Hacker Tells ‘Post,’” Jerusalem Post, January 16, 2012. 39 In addition to his actual...role as Imam Husayn’s standard bearer at Karbala. See Figure 19 in “Visual References.” 51 Sayyid Najmulhasan Karrarvi, Biography of Hazrat Abbas...since these declarations are not necessarily truthful or accurate.59 Martyr biographies are also usually highly and posthumously hagiographical in

  14. CTC Sentinel. Volume 6, Issue 11-12, November 2013

    Science.gov (United States)

    2013-11-01

    Libyan government today seeks only to strengthen its existence and power through presenting loyalty to these belligerent countries and offering...opened fire at customs police in Port Said near the Suez Canal, killing one person. – Bloomberg October 8 October 8, 2013 (IRAQ): A car bomb exploded...in front of a restaurant in the mainly Shi`a neighborhood of Zafaraniyya, killing three people. – AP, October 8 NOvEMBER 2013 . VoL 6. IssUE 11-12

  15. CTC Sentinel. Volume 6, Issue 4, April 2013

    Science.gov (United States)

    2013-04-01

    for the sake of the religion and the ‘end.’” Yaacoub detailed Rami’s instructions to set up e-mail accounts through which he could contact Rami...an FBI counterterrorism analyst, including work on the Millennial and September 11th plots. He also served as a State Department counterterrorism...December 12, 2011. 31 Ricardo Ravelo, Osiel: Vida y Tragedia de un Capo (Mexico City: Grijalbo, 2009). 32 Marc Lacey, “76 Arrested as Officials

  16. CTC Sentinel: January 2017, Volume 10, Issue 1

    Science.gov (United States)

    2017-01-01

    provements in our capability to quickly react, I think that even if there were an opening of the borders again, there would be a bet - ter response...yet to be examined in a court of law. If one thinks about the reliability of sources on a credibility continuum with trial evidence on the f Cases...delusional thinking or fixated behaviors. However, it will only ever be one of many drivers in an individual’s pathway to vio- lence. In many cases, it may

  17. CTC Sentinel. Volume 6, Issue 6, June 2013

    Science.gov (United States)

    2013-06-01

    Said Rahman’s successor, Khan Said, is often referred to as Sajna, which is Punjabi for “close friend.” Among younger TTP members, the 36-year-old...combination of hired criminals and ‘ Punjabi Taliban’ who snatch the hostages from their homes, vehicles and workplaces.”19 The work is distributed to

  18. CTC Sentinel. Volume 5, Issue 8, August 2012

    Science.gov (United States)

    2012-08-01

    Cyberterrorism: Capturing a Broad Range of Activities in Cyberspace By Jonalan Brickey 6 Pakistani Taliban Renew Attacks on Punjabi Heartland By Arif Rafiq...Agency, U.S. Northern Command, and U.S. Army Central Command. Pakistani Taliban Renew Attacks on Punjabi Heartland By Arif Rafiq after an extended...Lashkar-i-Tayyiba as well as the various Punjabi Taliban groups. 25 The Punjab police have made some important arrests in the past year. In

  19. CTC Sentinel. Volume 6, Issue 2, February 2013

    Science.gov (United States)

    2013-02-01

    trained “ Punjabi ” Taliban militants of Pakistani origin inside Afghan territory to pressure U.S. and coalition forces ahead of their withdrawal.31...described as being members of Punjabi mil i tant groups. – Australian, January 7 January 7, 2013 (AFGHANISTAN): A member of the Afghan Army

  20. CTC Sentinel. Volume 4, Issue 4, April 2011

    Science.gov (United States)

    2011-04-01

    Online, April 28, 2010. 3 Personal interview, Khalid Khwaja, March 2010. 4 Personal interview, Usman Punjabi , Winter 2010. 5 Hamid Mir, “What Was...members’ identities. It eventually emerged that the Punjabi Taliban—jihadists who left Kashmir-focused militant groups and joined the TTP—were...involved in the kidnapping operation. Usman Punjabi , or Mohammad Omar as he identified himself when contacting the media, became the link between

  1. CTC Sentinel (Volume 5, Issue 6, June 2012)

    Science.gov (United States)

    2012-06-01

    Los Zetas fought to retain control over a PEMEX well near Ciudad Mier, 3 Julie López, “The Zetas’ Bad Omen,” ReVista (Winter 2012). 4 John P...that there are 4,000-5,000 in- surgents and 300 people in leadership positions. See “Prayuth Calls for Inclusive Peace Talks,” Bangkok Post, April 3

  2. CTC Sentinel. Volume 4, Issue 6, June 2011

    Science.gov (United States)

    2011-06-01

    the majority of the merchant bourgeoisie has benefited enough from the last decade of economic l iberalization to priorit ize stabil i ty...relations between the population and the security apparatus. Since the rallying to the opposition of the merchant bourgeoisie of Damascus and

  3. CTC Sentinel. Volume 8, Issue 11, November/December 2015

    Science.gov (United States)

    2016-02-12

    adorns the masthead of the Islamic State’s English-lan- guage magazine Dabiq: The spark has been lit here in Iraq, and its heat will con- tinue to...However, there are signs that the Islamic State is under stress in critical areas. Its oil production, refining, and transport opera- tions are being...soldiers to the hudud; distributing zakat; and conducted animal breeding (camels, cows , ducks, sheep, goats, and geese) along with the usual activities

  4. CTC Sentinel. Volume 9, Issue 6, June 2016

    Science.gov (United States)

    2016-06-01

    supercomputers. municate securely. And it has become easier for terrorists to use the tools that already exist (Telegram, Whatsapp , Surespot, etc.) rather...19, 2015. 3 Cyrus Farivar, “ WhatsApp is now most widely used end-to-end crypto tool on the planet,” Ars Technica, April 5, 2016. 4 Russell Brandom...Google’s Allo runs on the same encryption tech that powers WhatsApp ,” The Verge, May 18, 2016. 5 “How to communicate with us,” Inspire issue 10

  5. CTC Sentinel. Volume 8, Issue 8. August 2015

    Science.gov (United States)

    2015-08-01

    of the “inner-city” gang phenomenon. Young Muslim men with a history of social and criminal delinquency are joining up with the Islamic State as... history of delinquency joining up with al-Qa`ida in the tribal areas of Pakistan in the late 2000s. But it has now become a much bigger phenomenon...8 2 history beyond the required defenses of Egypt’s eastern gate to the Levant. Modern Egypt would prove no different. The Suez Canal created a

  6. CTC Sentinel. Volume 9, Issue 10, October 2016

    Science.gov (United States)

    2016-10-01

    accept the kind of autocrats who sparked such unrest in the first place. Messaging Western leaders , particularly those in the United States...Salam (Peace Companies), and Sayyid al-Shuhada.19 From June 13, 2014, Prime Minister Nouri al-Maliki appointed Badr leader Hadi al- Ameri as the...signed by AAH threatened families living in Muqdadiyah unless they left their homes in 48 hours. Authors’ SIGACT dataset. v Badr leader Hadi al-Amiri

  7. CTC Sentinel. Volume 4, Issue 7, July 2011

    Science.gov (United States)

    2011-07-01

    all, and that the benefits of a merger at a time when al-Qa`ida needs to project power and influence outweigh any lingering concerns about al...given backlashes it has previously faced from franchisees ’ use of violent tactics against civilian populations. Another factor may be reluctance...Qaeda central,” they “can get the benefits ...that they want from this type of militant transnational Islamism, while still maintaining their

  8. Effect on HBs antigen clearance of addition of pegylated interferon alfa-2a to nucleos(t)ide analogue therapy versus nucleos(t)ide analogue therapy alone in patients with HBe antigen-negative chronic hepatitis B and sustained undetectable plasma hepatitis B virus DNA: a randomised, controlled, open-label trial.

    Science.gov (United States)

    Bourlière, Marc; Rabiega, Pascaline; Ganne-Carrie, Nathalie; Serfaty, Lawrence; Marcellin, Patrick; Barthe, Yoann; Thabut, Dominique; Guyader, Dominique; Hezode, Christophe; Picon, Magali; Causse, Xavier; Leroy, Vincent; Bronowicki, Jean Pierre; Carrieri, Patrizia; Riachi, Ghassan; Rosa, Isabelle; Attali, Pierre; Molina, Jean Michel; Bacq, Yannick; Tran, Albert; Grangé, Jean Didier; Zoulim, Fabien; Fontaine, Hélène; Alric, Laurent; Bertucci, Inga; Bouvier-Alias, Magali; Carrat, Fabrice

    2017-03-01

    Findings from uncontrolled studies suggest that addition of pegylated interferon in patients with HBe antigen (HBeAg)-negative chronic hepatitis B receiving nucleos(t)ide analogues with undetectable plasma hepatitis B virus (HBV) DNA might increase HBs antigen (HBsAg) clearance. We aimed to assess this strategy. In this randomised, controlled, open-label trial, we enrolled patients aged 18-75 years with HBeAg-negative chronic hepatitis B and documented negative HBV DNA while on stable nucleos(t)ide analogue regimens for at least 1 year from 30 hepatology tertiary care wards in France. Patients had to have an alanine aminotransferase concentration of less than or equal to five times the upper normal range, no hepatocellular carcinoma, and a serum α fetoprotein concentration of less than 50 ng/mL, normal dilated fundus oculi examination, and a negative pregnancy test in women. Patients with contraindications to pegylated interferon were not eligible. A centralised randomisation used computer-generated lists of random permuted blocks of four with stratification by HBsAg titres (sida et les hépatites virales (France Recherche Nord&sud Sida-vih Hepatites). Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. Status of ITER

    International Nuclear Information System (INIS)

    Aymar, R.

    2002-01-01

    At the end of engineering design activities (EDA) in July 2001, all the essential elements became available to make a decision on construction of ITER. A sufficiently detailed and integrated engineering design now exists for a generic site, has been assessed for feasibility, and costed, and essential physics and technology R and D has been carried out to underpin the design choices. Formal negotiations have now begun between the current participants--Canada, Euratom, Japan, and the Russian Federation--on a Joint Implementation Agreement for ITER which also establishes the legal entity to run ITER. These negotiations are supported on technical aspects by Coordinated Technical Activities (CTA), which maintain the integrity of the project, for the good of all participants, and concentrate on preparing for procurement by industry of the longest lead items, and for formal application for a construction license with the host country. This paper highlights the main features of the ITER design. With cryogenically-cooled magnets close to neutron-generating plasma, the design of shielding with adequate access via port plugs for auxiliaries such as heating and diagnostics, and of remote replacement and refurbishing systems for in-vessel components, are particularly interesting nuclear technology challenges. Making a safety case for ITER to satisfy potential regulators and to demonstrate, as far as possible at this stage, the environmental attractiveness of fusion as an energy source, is also important. The paper gives illustrative details on this work, and an update on the progress of technical preparations for construction, as well as the status of the above negotiations

  10. Status of thorium technology

    International Nuclear Information System (INIS)

    Garg, R.K.; Raghavan, R.V.; Karve, V.M.; Narayandas, G.R.

    1977-01-01

    Although a number of studies have been conducted in various countries to evolve reactor systems based on thorium fuel cycle, its use, so far, is limited to only a few reactors. However, for countries having large reserves of thorium, its utilization is of great significance for their nuclear power programmes. Reasonably assured world resources of thorium in the lower price range have been estimated at more than 500,000 tons of ThO 2 . While most of these resources are in placer deposits in various parts of the world, some vein deposits and uranium ores are other important sources of thorium. Monazite, the most important mineral of thorium, is found in the beach sand deposits along with other heavy minerals like ilmenite, rutile, zircon, and sillimanite etc. Mining of these deposits is usually carried out by suction dredging and separation of monazite from other minerals is effected by a combination of magnetic, electrostatic and gravity separation techniques. Chemical processing of monazite is carried out either by sulphuric acid or caustic treatment, followed by separation of the rare earths and thorium by partial precipitation or leaching. The thorium concentrate is further processed to obtain mantle grade thorium nitrate by chemical purification steps whereas solvent extraction using TBP is adopted for making nuclear-grade material. The purified thorium nitrate is converted to the oxide usually by precipitation as oxalate followed by calcination. The oxide is reduced directly with calcium or converted to the chloride or fluoride and then reduced by calcium or magnesium to obtain thorium metal. Various fuel designs based on the metal or its alloys, mixed oxides or carbides, and dispersed type fuel elements have been developed and accordingly, different fabrication techniques have been employed. Work on irradiation of thorium containing fuel elements and separation of U 233 is being carried out. This paper reviews the status of thorium technology in the world with

  11. Status of funded actions

    International Nuclear Information System (INIS)

    2003-01-01

    The GEDEPEON status workshop is organised to review the GEDEPEON research actions, which have been funded in 2003. Presentations are made by research teams actively involved in GEDEPEON research areas. Speakers were invited to show how the presented research data are related to the general goals of transmutation, for which 2006 is an important milestone, and innovative systems. This document gathers 18 presentations (slides) among the 32 given at this workshop and dealing with: 1 - nuclear data: measurement of cross-sections of neutron induced reactions at the nTof time of flight facilities of CERN and of Gelina at Geel (F. Gunsing), study of (n,xn) reactions thanks to prompt gamma spectroscopy (M. Kerveno), iodine 129 cross-sections (G. Noguere); 2 - reactor physics/cycles: CEA-CNRS scenarios (F. Varaine, D. Heuer), analysis of uncertainties and sensitivity factors of nuclear data on innovative systems (molten-salt reactors) (A. Bidaud); 3 - materials: contribution to the study of T91 steel fatigue by lead-bismuth (D. Gorse), kinetics and mechanisms of fatigue by liquid metals (V. Laporte), studies of molten salts corrosion in future reactors (S. Sanchez), stress-induced fatigue by liquid metal (A. Verleene), thermodynamic study of the Bi-Fe-Hg-O-Pb quinary system (A. Maitre), synchrotron imaging study of fatigue by liquid metals (D. Bellet); 4 - future systems: molten salts reprocessing strategy - impact on the molten salt reactors neutronics (L. Mathieu), microscopy technique for the characterization of the thermal properties of inert materials for gas-cooled reactors (L. David), modeling and application of sub-atomic phenomena (J. Maillard), forecasting of the chemical compatibility between fissile compounds and inert materials in future high temperature reactors using a thermodynamical approach (A. Maitre), hydrogen production by thermochemical cycles (S. Colette), development of Ni-W refractory alloys for high temperature and molten salts reactors (J

  12. Between Status and Contract?

    Directory of Open Access Journals (Sweden)

    Thorsten Keiser

    2013-01-01

    Full Text Available This contribution deals with unfree labour in Germany from the early modern age until the beginning of the 20th century. It presents the main conclusions of a book published in 2013 on this subject in German. Unfree labour is not identified in the first place with slavery or any other labour relationship based on status. Instead, this study aims at an analysis of freedom and coercion in contractual labour relationships. It will be argued that in Germany contractual labour relationships before 1800 were embedded in a legal system that strongly restricted contractual autonomy and aimed at the suppression of free labour markets. The scope of this legislation was to guarantee efficient labour performance, which was not only perceived as being in the personal interest of an employer, but as a fundamental element of the common good. After 1800 the system changed to more incentive-based legislation that established freedom of contract for labour relations. Nevertheless, coercion in order to perform the contractual duties of a work contract remained important for many groups of workers, especially farmhands and industrial workers. The last criminal sanctions for breaches of labour contracts were only abolished in the revolution of 1919. This development shows the difficulties German law had in extending the principles of private law to workers. When a system of free labour was fully established, the issue of unemployment and economic problems, especially in the Weimar Republic, required a new system of protective rules. The history of free market based labour contracts in Germany was therefore very short, with state intervention shi ing from control and coercion to social assistance.

  13. Treatment of Established Status Epilepticus.

    Science.gov (United States)

    Falco-Walter, Jessica J; Bleck, Thomas

    2016-04-25

    Status epilepticus is the most severe form of epilepsy, with a high mortality rate and high health care costs. Status epilepticus is divided into four stages: early, established, refractory, and super-refractory. While initial treatment with benzodiazepines has become standard of care for early status epilepticus, treatment after benzodiazepine failure (established status epilepticus (ESE)) is incompletely studied. Effective treatment of ESE is critical as morbidity and mortality increases dramatically the longer convulsive status epilepticus persists. Phenytoin/fosphenytoin, valproic acid, levetiracetam, phenobarbital, and lacosamide are the most frequently prescribed antiseizure medications for treatment of ESE. To date there are no class 1 data to support pharmacologic recommendations of one agent over another. We review each of these medications, their pharmacology, the scientific evidence in support and against each in the available literature, adverse effects and safety profiles, dosing recommendations, and limitations of the available evidence. We also discuss future directions including the established status epilepticus treatment trial (ESETT). Substantial further research is urgently needed to identify these patients (particularly those with non-convulsive status epilepticus), elucidate the most efficacious antiseizure treatment with head-to-head randomized prospective trials, and determine whether this differs for convulsive vs. non-convulsive ESE.

  14. Treatment of Established Status Epilepticus

    Science.gov (United States)

    Falco-Walter, Jessica J.; Bleck, Thomas

    2016-01-01

    Status epilepticus is the most severe form of epilepsy, with a high mortality rate and high health care costs. Status epilepticus is divided into four stages: early, established, refractory, and super-refractory. While initial treatment with benzodiazepines has become standard of care for early status epilepticus, treatment after benzodiazepine failure (established status epilepticus (ESE)) is incompletely studied. Effective treatment of ESE is critical as morbidity and mortality increases dramatically the longer convulsive status epilepticus persists. Phenytoin/fosphenytoin, valproic acid, levetiracetam, phenobarbital, and lacosamide are the most frequently prescribed antiseizure medications for treatment of ESE. To date there are no class 1 data to support pharmacologic recommendations of one agent over another. We review each of these medications, their pharmacology, the scientific evidence in support and against each in the available literature, adverse effects and safety profiles, dosing recommendations, and limitations of the available evidence. We also discuss future directions including the established status epilepticus treatment trial (ESETT). Substantial further research is urgently needed to identify these patients (particularly those with non-convulsive status epilepticus), elucidate the most efficacious antiseizure treatment with head-to-head randomized prospective trials, and determine whether this differs for convulsive vs. non-convulsive ESE. PMID:27120626

  15. Large block test status report

    International Nuclear Information System (INIS)

    Wilder, D.G.; Lin, W.; Blair, S.C.

    1997-01-01

    This report is intended to serve as a status report, which essentially transmits the data that have been collected to date on the Large Block Test (LBT). The analyses of data will be performed during FY98, and then a complete report will be prepared. This status report includes introductory material that is not needed merely to transmit data but is available at this time and therefore included. As such, this status report will serve as the template for the future report, and the information is thus preserved

  16. Status of solar neutrino experiments

    International Nuclear Information System (INIS)

    Beier, E.W.; Davis, R. Jr.; Kim, S.B.; Jelley, N.

    1990-01-01

    A summary of the status of four solar neutrino experiments is presented. The Homestake 37 Cl data are presented and the possible time dependence of the data is addressed. Data from 1040 days of operation of the Kamiokande II detector are presented next. The status of the 71 Ga experiment in the Baksan Neutrino Observatory, which has operated for a short time, is discussed. The summary concludes with a discussion of the status of the Sudbury Neutrino Observatory, which has been under construction since the beginning of 1990. 7 refs., 6 figs

  17. Status of women microbiologists.

    Science.gov (United States)

    Kashket, E R; Robbins, M L; Leive, L; Huang, A S

    1974-02-08

    beginning student. For older women, there must be increased placement in positions of responsibility and visibility. Protective practices that discourage women from entering arenas of competition can only be viewed as discrimination on the basis of sex, since women professionals are rarely given the choice between being protected and being independent. Unexpectedly, this study illustrates the lower status of another group of individuals who are considered deviants from the expected roles of the established society-single men with doctorates, who were found in the positions predominately filled by women. In conclusion, this study of a select group of scientists probably has general applicability to all women professionals in their roles vis-à-vis men. Examination and documentation of discriminatory practices based on sex points to the areas in which women must direct their demands for equality.

  18. Experimental status of quantum electrodynamics

    International Nuclear Information System (INIS)

    Drell, S.D.

    1978-10-01

    This review of the experimental status of quantum electrodynamics covers the fine structure constant, the muon g-2 value, the Lamb shift in hydrogen, the finite proton radius, progress in muonium, and positronium. 37 references

  19. Status of Fermilab E-710

    International Nuclear Information System (INIS)

    Rubinstein, R.

    1993-08-01

    This report give the current status of E-710, an experiment at the Fermilab bar pp Tevatron Collider to measure elastic scattering, total cross sections and diffraction dissociation up to √s = 1.8 TeV

  20. Status of time reversal invariance

    International Nuclear Information System (INIS)

    Henley, E.M.

    1989-01-01

    Time Reversal Invariance is introduced, and theories for its violation are reviewed. The present experimental and theoretical status of Time Reversal Invariance and tests thereof will be presented. Possible future tests will be discussed. 30 refs., 2 figs., 1 tab

  1. Fusion technology status and requirements

    International Nuclear Information System (INIS)

    Thomassen, K.I.

    1982-01-01

    This paper summarizes the status of fusion technology and discusses the requirements to be met in order to build a demonstration fusion plant. Strategies and programmatic considerations in pursuing engineering feasibility are also outlined

  2. Refugee status determination: three challenges

    Directory of Open Access Journals (Sweden)

    Martin Jones

    2009-04-01

    Full Text Available Refugee status determination (RSD, which is vital to the protection of so many asylum seekers worldwide, is at best an imperfect, haphazard and challenging process. It merits greater attention and appropriate reform.

  3. Status report on pavement management.

    Science.gov (United States)

    1984-01-01

    This report traces the developments in pavement management in the Virginia Department of Highways and Transportation from the initial efforts in the mid-1970s through early 1984. Included are status reports on pavement management for the interstate, ...

  4. Fukushima Daiichi Status Report. 28 June 2012

    International Nuclear Information System (INIS)

    2012-01-01

    The IAEA issues regular status reports to the public on the current status of the Fukushima Daiichi Nuclear Power Plant, including information on environmental radiation monitoring, the status of workers, and current conditions on-site at the plant.

  5. Coagulation Status in Hidradenitis Suppurativa

    DEFF Research Database (Denmark)

    Miller, Iben Marie; Johansen, Maria Egede; Mogensen, Ulla B

    2015-01-01

    BACKGROUND: Chronic inflammatory diseases other than hidradenitis suppurativa (HS) have been associated with prothrombotic/hypercoagulable status. OBJECTIVE: To investigate a possible association between the chronic inflammatory skin disease HS and prothrombotic/hypercoagulable state. METHODS: We.......3432). CONCLUSION: We did not find an association between HS and prothrombotic/hypercoagulable status. Thus, thrombocytes may not be activated in HS. Furthermore, INR may not be affected in HS, suggesting that intrinsic and vitamin K-dependent coagulation factors appear unaffected....

  6. The status of BAT detector

    Science.gov (United States)

    Lien, Amy; Markwardt, Craig B.; Krimm, Hans Albert; Barthelmy, Scott D.; Cenko, Bradley

    2018-01-01

    We will present the current status of the Swift/BAT detector. In particular, we will report the updated detector gain calibration, the number of enable detectors, and the global bad time intervals with potential calibration issues. We will also summarize the results of the yearly BAT calibration using the Crab nebula. Finally, we will discuss the effects on the BAT survey, such as the sensitivity, localization, and spectral analysis, due to the changes in detector status.

  7. Present status of CP violation

    International Nuclear Information System (INIS)

    Ng, J.N.

    1989-06-01

    A review of the status of CP violation in kaons is given. Status of our knowledge of quark mixing angles in the standard six quark model is presented. The role Β d o - Βd o transition plays in this study is examined. A comparison of the estimates of CP violation effects from models beyond the standard one is given. Other experiments that have the capability of testing different CP violation models are also discussed. (Author) 35 refs., 6 figs., tab

  8. Status report, canister fabrication

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, Claes-Goeran; Eriksson, Peter; Westman, Marika [Swedish Nuclear Fuel and Waste Management Co., Stockholm (Sweden); Emilsson, Goeran [CSM Materialteknik AB, Linkoeping (Sweden)

    2004-06-01

    The report gives an account of the development of material and fabrication technology for copper canisters with cast inserts during the period from 2000 until the start of 2004. The engineering design of the canister and the choice of materials in the constituent components described in previous status reports have not been significantly changed. In the reference canister, the thickness of the copper shell is 50 mm. Fabrication of individual components with a thinner copper thickness is done for the purpose of gaining experience and evaluating fabrication and inspection methods for such canisters. As a part of the development of cast inserts, computer simulations of the casting processes and techniques used at the foundries have been performed for the purpose of optimizing the material properties. These properties have been evaluated by extensive tensile testing and metallographic inspection of test material taken from discs cut at different points along the length of the inserts. The testing results exhibit a relatively large spread. Low elongation values in certain tensile test specimens are due to the presence of poorly formed graphite, porosities, slag or other casting defects. It is concluded in the report that it will not be possible to avoid some presence of observed defects in castings of this size. In the deep repository, the inserts will be exposed to compressive loading and the observed defects are not critical for strength. An analysis of the strength of the inserts and formulation of relevant material requirements must be based on a statistical approach with probabilistic calculations. This work has been initiated and will be concluded during 2004. An initial verifying compression test of a canister in an isostatic press has indicated considerable overstrength in the structure. Seamless copper tubes are fabricated by means of three methods: extrusion, pierce and draw processing, and forging. It can be concluded that extrusion tests have revealed a

  9. Status report, canister fabrication

    International Nuclear Information System (INIS)

    Andersson, Claes-Goeran; Eriksson, Peter; Westman, Marika; Emilsson, Goeran

    2004-06-01

    The report gives an account of the development of material and fabrication technology for copper canisters with cast inserts during the period from 2000 until the start of 2004. The engineering design of the canister and the choice of materials in the constituent components described in previous status reports have not been significantly changed. In the reference canister, the thickness of the copper shell is 50 mm. Fabrication of individual components with a thinner copper thickness is done for the purpose of gaining experience and evaluating fabrication and inspection methods for such canisters. As a part of the development of cast inserts, computer simulations of the casting processes and techniques used at the foundries have been performed for the purpose of optimizing the material properties. These properties have been evaluated by extensive tensile testing and metallographic inspection of test material taken from discs cut at different points along the length of the inserts. The testing results exhibit a relatively large spread. Low elongation values in certain tensile test specimens are due to the presence of poorly formed graphite, porosities, slag or other casting defects. It is concluded in the report that it will not be possible to avoid some presence of observed defects in castings of this size. In the deep repository, the inserts will be exposed to compressive loading and the observed defects are not critical for strength. An analysis of the strength of the inserts and formulation of relevant material requirements must be based on a statistical approach with probabilistic calculations. This work has been initiated and will be concluded during 2004. An initial verifying compression test of a canister in an isostatic press has indicated considerable overstrength in the structure. Seamless copper tubes are fabricated by means of three methods: extrusion, pierce and draw processing, and forging. It can be concluded that extrusion tests have revealed a

  10. Conceptions of nuclear threshold status

    International Nuclear Information System (INIS)

    Quester, G.H.

    1991-01-01

    This paper reviews some alternative definitions of nuclear threshold status. Each of them is important, and major analytical confusions would result if one sense of the term is mistaken for another. The motives for nations entering into such threshold status are a blend of civilian and military gains, and of national interests versus parochial or bureaucratic interests. A portion of the rationale for threshold status emerges inevitably from the pursuit of economic goals, and another portion is made more attraction by the derives of the domestic political process. Yet the impact on international security cannot be dismissed, especially where conflicts among the states remain real. Among the military or national security motives are basic deterrence, psychological warfare, war-fighting and, more generally, national prestige. In the end, as the threshold phenomenon is assayed for lessons concerning the role of nuclear weapons more generally in international relations and security, one might conclude that threshold status and outright proliferation coverage to a degree in the motives for all of the states involved and in the advantages attained. As this paper has illustrated, nuclear threshold status is more subtle and more ambiguous than outright proliferation, and it takes considerable time to sort out the complexities. Yet the world has now had a substantial amount of time to deal with this ambiguous status, and this may tempt more states to exploit it

  11. Is Subjective Status Influenced by Psychosocial Factors?

    OpenAIRE

    Lundberg, Johanna; Kristenson, Margareta

    2008-01-01

    Objective Associations between subjective status and health are still relatively unexplored. This study aimed at testing whether subjective status is uniquely confounded by psychosocial factors compared to objective status, and what factors that may predict subjective status. Design A cross-sectional analysis of a population-based, random sample of 795 middle-aged men and women from the southeast of Sweden. Questionnaires included subjective status, objective measures of socioeconomic status,...

  12. Overweight but unseen: a review of the underestimation of weight status and a visual normalization theory.

    Science.gov (United States)

    Robinson, E

    2017-10-01

    Although overweight and obesity are widespread across most of the developed world, a considerable body of research has now accumulated, which suggests that adiposity often goes undetected. A substantial proportion of individuals with overweight or obesity do not identify they are overweight, and large numbers of parents of children with overweight or obesity fail to identify their child as being overweight. Lay people and medical practitioners are also now poor at identifying overweight and obesity in others. A visual normalization theory of the under-detection of overweight and obesity is proposed. This theory is based on the notion that weight status is judged relative to visual body size norms. Because larger body sizes are now common, this has caused a recalibration to the range of body sizes that are perceived as being 'normal' and increased the visual threshold for what constitutes 'overweight'. Evidence is reviewed that indicates this process has played a significant role in the under-detection of overweight and obesity. The public health relevance of the under-detection of overweight and obesity is also discussed. © 2017 The Authors. Obesity Reviews published by John Wiley & Sons Ltd on behalf of World Obesity.

  13. Periodontal status and dental care in HIV seropositive patients

    Directory of Open Access Journals (Sweden)

    Maria Sueli Marques Soares

    2009-12-01

    Full Text Available Objective: The aim of the study was to evaluate the correlation between CD4+ cell count and viral load with periodontal and dental status in HIV seropositive patient. Methods: Forty HIV seropositive patients were selected from the dental clinic of the Clementino Fraga Hospital in João Pessoa, Paraíba, Brazil. The Community Periodontal Index, Simplified Oral Hygiene Index and Decayed, Missing or Filled Teeth Index were determined. The values of CD4+ lymphocyte count and viral load were collected from the medical records. Descriptive analysis was made and Spearman’s correlation test was applied, with values of p<0.05 being significant. Results: HIV seropositive patients were aged 33 to 47 years (mean = 40 years, 26 were men and 14 women. The mean CD4+ lymphocyte count was 507.82±306.4 cells/mm3, with 41% being a high, 38.5% a medium and 20.5% a low level. Sixty-five percent of the patients had undetectable viral load, 12.5% had a high, 5% a low and 5% a medium viral load. Most patients (87.5% presented with periodontal disease, calculus was the most frequent condition (40%. The mean Decayed, Missing or Filled Tooth Index was 19.7±6.8, with prevalence of the missing component. There was significant statistical correlation between the CD4+ count and the periodontal condition, p=0.046. There was no significant correlation between the CD4+ count and the Decayed, Missing or Filled Teeth Index (p=0.469 and the Simplified Oral Hygiene Index (p=0.189 indexes, and between viral load and Decayed, Missing or Filled Teeth Index (p=0.452, the Simplified Oral Hygiene Index (p=0.158 and Community Periodontal Index (p=0.216. Conclusion: The periodontal condition was influenced to a greater by the CD4+ cell count than the viral load, while there was no correlation between the decayed condition and the CD4+ cell count or the viral load condition.

  14. LARGE BLOCK TEST STATUS REPORT

    International Nuclear Information System (INIS)

    D.G. WILDER, W. LIN, S.C. BLAIR, T. BUSCHECK, R.C. CARLSON, K. LEE, A. MEIKE, A.L. RAMIREZ, J.L. WAGONER, AND J. WANG

    1997-01-01

    This report is intended to serve as a status report, which essentially transmits the data that have been collected to date on the Large Block Test (LBT). The analyses of data will be performed during FY98, and then a complete report will be prepared. This status report includes introductory material that is not needed merely to transmit data but is available at this time and therefore included. As such, this status report will serve as the template for the future report, and the information is thus preserved. The United States Department of Energy (DOE) is investigatinq the suitability of Yucca Mountain (YM) as a potential site for the nation's first high-level nuclear waste repository. As shown in Fig. 1-1, the site is located about 120 km northwest of Las Vegas, Nevada, in an area of uninhabited desert

  15. Predicting outcome of status epilepticus.

    Science.gov (United States)

    Leitinger, M; Kalss, G; Rohracher, A; Pilz, G; Novak, H; Höfler, J; Deak, I; Kuchukhidze, G; Dobesberger, J; Wakonig, A; Trinka, E

    2015-08-01

    Status epilepticus (SE) is a frequent neurological emergency complicated by high mortality and often poor functional outcome in survivors. The aim of this study was to review available clinical scores to predict outcome. Literature review. PubMed Search terms were "score", "outcome", and "status epilepticus" (April 9th 2015). Publications with abstracts available in English, no other language restrictions, or any restrictions concerning investigated patients were included. Two scores were identified: "Status Epilepticus Severity Score--STESS" and "Epidemiology based Mortality score in SE--EMSE". A comprehensive comparison of test parameters concerning performance, options, and limitations was performed. Epidemiology based Mortality score in SE allows detailed individualization of risk factors and is significantly superior to STESS in a retrospective explorative study. In particular, EMSE is very good at detection of good and bad outcome, whereas STESS detecting bad outcome is limited by a ceiling effect and uncertainty of correct cutoff value. Epidemiology based Mortality score in SE can be adapted to different regions in the world and to advances in medicine, as new data emerge. In addition, we designed a reporting standard for status epilepticus to enhance acquisition and communication of outcome relevant data. A data acquisition sheet used from patient admission in emergency room, from the EEG lab to intensive care unit, is provided for optimized data collection. Status Epilepticus Severity Score is easy to perform and predicts bad outcome, but has a low predictive value for good outcomes. Epidemiology based Mortality score in SE is superior to STESS in predicting good or bad outcome but needs marginally more time to perform. Epidemiology based Mortality score in SE may prove very useful for risk stratification in interventional studies and is recommended for individual outcome prediction. Prospective validation in different cohorts is needed for EMSE, whereas

  16. [Nutritional status and the relationship regarding functional status after stroke].

    Science.gov (United States)

    López Espuela, Fidel; Portilla Cuenca, Juan Carlos; Holguín Mohedas, Marta; Párraga Sánchez, José Manuel; Cordovilla-Guardia, Sergio; Casado Naranjo, Ignacio

    2017-09-14

    To assess the nutritional status (NS) of patients at three months of suffering a stroke, and to establish the relationship between functional recovery and complications in this period. A cross-sectional observational study evaluating the NS of patients older than 65 years at three months of having a stroke. The NS was assessed using the Mini Nutritional Assessment (MNA). Sociodemographic and anthropometric data, cardiovascular risk factors, as well as functional status (through the Barthel index and the modified Rankin scale) and the presented complications were collected. One hundred and three patients were included, with a medium age of 75.81 (± 6.73). The MNA score was 23.13 points (± 4.47); 8.2% had malnutrition and 38.1% had risk of malnutrition. There were no differences in the NS between women and men (p = 0.076) neither relation of the NS with age. NS deficiency was associated with poorer function (r = 0.608; p nutritional status had a better quality of life (r = 0.506; p < 0.001). It was also associated with poorer socioeconomic status (p = 0.020) and institutionalization (p = 0.004). The risk of malnutrition is common in stroke survivors at the short-term. This NS is associated with a worse functional situation and self-perceived quality of life and with a higher rate of complications. Early detection of the risk of malnutrition is essential in patients who have suffered a stroke.

  17. Relationships between Psychosocial Resilience and Physical Health Status of Western Australian Urban Aboriginal Youth.

    Directory of Open Access Journals (Sweden)

    Katrina D Hopkins

    Full Text Available Psychosocial processes are implicated as mediators of racial/ethnic health disparities via dysregulation of physiological responses to stress. Our aim was to investigate the extent to which factors previously documented as buffering the impact of high-risk family environments on Aboriginal youths' psychosocial functioning were similarly beneficial for their physical health status.We examined the relationship between psychosocial resilience and physical health of urban Aboriginal youth (12-17 years, n = 677 drawn from a representative survey of Western Australian Aboriginal children and their families. A composite variable of psychosocial resilient status, derived by cross-classifying youth by high/low family risk exposure and normal/abnormal psychosocial functioning, resulted in four groups- Resilient, Less Resilient, Expected Good and Vulnerable. Separate logistic regression modeling for high and low risk exposed youth revealed that Resilient youth were significantly more likely to have lower self-reported asthma symptoms (OR 3.48, p<.001 and carer reported lifetime health problems (OR 1.76, p<.04 than Less Resilient youth.The findings are consistent with biopsychosocial models and provide a more nuanced understanding of the patterns of risks, resources and adaptation that impact on the physical health of Aboriginal youth. The results support the posited biological pathways between chronic stress and physical health, and identify the protective role of social connections impacting not only psychosocial function but also physical health. Using a resilience framework may identify potent protective factors otherwise undetected in aggregated analyses, offering important insights to augment general public health prevention strategies.

  18. Status of spallation neutron source

    Energy Technology Data Exchange (ETDEWEB)

    Oyama, Yukio [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1997-03-01

    Existing and planned facilities using proton accelerator driven spallation neutron source are reviewed. These include new project of neutron science proposed from Japan Atomic Energy Research Institute. The present status of facility requirement and accelerator technology leads us to new era of neutron science such as neutron scattering research and nuclear transmutation study using very intense neutron source. (author)

  19. Status of Japanese university reactors

    International Nuclear Information System (INIS)

    Fujita, Yoshiaki

    1999-01-01

    Status of Japanese university reactors, their role and value in research and education, and the spent fuel problem are presented. Some of the reactors are now faced by severe difficulties in continuing their operation services. The point of measures to solve the difficulties is suggested. (author)

  20. The Epistemic Status of Intelligence

    DEFF Research Database (Denmark)

    Rønn, Kira Vrist; Høffding, Simon

    2012-01-01

    We argue that the majority of intelligence definitions fail to recognize that the normative epistemic status of intelligence is knowledge and not an inferior alternative. We refute the counter-arguments that intelligence ought not to be seen as knowledge because of 1) its action-oriented scope...... and robustness of claims to intelligence-knowledge can be assessed....

  1. RD39 Status Report 2009

    CERN Document Server

    Anbinderis, P; Bates, R; Bol, H; Buttar, C; Chen, W; Cindro, V; de Boer, W; Eremin, V; Gaubas, E; Grigoriev, E; Härkönen, J; Heijne, E; Heising, S; Ilyashenko, I; Kalesinskas, V; Krause, M; Li, Z; Luukka, P; Mäenpää, T; Mandi, I; Mikuz, M; Mueller, S; Niinikoski, T; O'Shea, V; Parkes, C; Pusa, P; Räisänen, J; Reinhardt, S; Spiegel, L; Tuominen, E; Tuovinen, E; Vaitkus, J; Väyrynen, S; Verbitskaya, E; Zavrtanik, M; CERN. Geneva. The LHC experiments Committee; LHCC

    2010-01-01

    RD39 Status Report 2009. CERN RD39 Collaboration is developing super-radiation hard cryogenic silicon detectors for applications of LHC experiments and their future upgrades. The activities of RD39 Collaboration were focused in 2009 on concept of charge injected detector (CID).

  2. ANTIOXIDANT STATUS IN DIABETIC NEUROPATHY

    Directory of Open Access Journals (Sweden)

    Giriraja Vrushabaiah Kanakapura

    2017-09-01

    Full Text Available BACKGROUND Diabetic neuropathy, retinopathy and nephropathy are the chronic complications of diabetes mellitus. Neuropathy, retinopathy and nephropathy are microvascular complication of diabetes mellitus. Antioxidant status is reduced in DM-induced retinopathy and nephropathy. Present study is undertaken to evaluate the degree of oxidative stress in diabetic neuropathy patients. The aim of the study is to study on oxidative stress as measured by lipid peroxidation marker, malondialdehyde and antienzyme status in type II DM patients with neuropathy and compared them with a controlled nondiabetic group. MATERIALS AND METHODS The study included 100 subjects from Sapthagiri Medical College, Bangalore, from January 1, 2015, to December 31, 2015, of age group 50 to 70 yrs. out of which 50 patients were non-insulin-dependent DM with neuropathy and rest 50 age and sex matched apparently healthy individuals (control group. Antioxidant status was assessed by measuring superoxide dismutase (SOD, glutathione peroxidase (GPx, glutathione reductase (GR, Catalase and Reduced Glutathione (GSH. RESULTS It showed a significant increase p<0.001 in FBS, PPBS, TC, TG, LDL, VLDL, CAT, MDA, while HDL, GSH, GPX, GR and SOD were found to be decreased significantly (p 0.001. CONCLUSION MDA was significantly elevated in diabetic group, whereas antioxidant enzymes superoxide dismutase, glutathione peroxidase, glutathione reductase and reduced glutathione were significantly decreased, which might be helpful in risk assessment of various complications of DM. The data suggests that alteration in antioxidant status and MDA may help to predict the risk of diabetic neuropathy.

  3. DYMAC system: status and experience

    International Nuclear Information System (INIS)

    Malanify, J.J.

    1980-01-01

    The Dynamic Materials Accountability (DYMAC) system has been in operation at the Plutonium Processing Facility at the Los Alamos Scientific Laboratory since January 1978. The current status of this development and demonstration program, as well as the achieved operational experience, is reported

  4. The Medicina Station Status Report

    Science.gov (United States)

    Orfei, Alessandro; Orlati, Andrea; Maccaferri, Giuseppe

    2013-01-01

    General information about the Medicina Radio Astronomy Station, the 32-m antenna status, and the staff in charge of the VLBI observations is provided. In 2012, the data from geodetic VLBI observations were acquired using the Mark 5A recording system with good results. Updates of the hardware were performed and are briefly described.

  5. Present status of processing method

    Energy Technology Data Exchange (ETDEWEB)

    Kosako, Kazuaki [Sumitomo Atomic Energy Industries Ltd., Tokyo (Japan)

    1998-11-01

    Present status of processing method for a high-energy nuclear data file was examined. The NJOY94 code is the only one available to the processing. In Japan, present processing used NJOY94 is orienting toward the production of traditional cross section library, because a high-energy transport code using a high-energy cross section library is indistinct. (author)

  6. Berber Dialects. Materials Status Report.

    Science.gov (United States)

    Center for Applied Linguistics, Washington, DC. Language/Area Reference Center.

    The materials status report for the Berber languages, minority languages spoken in northern Africa, is one of a series intended to provide the nonspecialist with a picture of the availability and quality of texts for teaching various languages to English speakers. The report consists of: (1) a brief narrative description of the Berber language,…

  7. Experimental Status of B Physics

    International Nuclear Information System (INIS)

    Stone, Sheldon

    2006-01-01

    A short summary is given of the current status of B physics. Reasons for physics beyond the Standard Model are discussed. Constraints on New Physics are given using measurements of B mixing, BS mixing, and CP violation, along with |Vub|. Future goals, and upcoming new experiments are also mentioned

  8. Socioeconomic status and fertility decline

    DEFF Research Database (Denmark)

    Dribe, Martin; Breschi, Marco; Gagnon, Alain

    2017-01-01

    America to analyse the relationship between socio-economic status and fertility during the fertility transition. Using comparable analytical models and class schemes for each population, we examined the changing socio-economic differences in marital fertility and related these to common theories...

  9. The status of cold fusion

    Science.gov (United States)

    Storms, E.

    This report attempts to update the status of the phenomenon of cold fusion. The new field is continuing to grow as a variety of nuclear reactions are discovered to occur in a variety of chemical environments at modest temperatures. However, it must be cautioned that most scientists consider cold fusion as something akin to UFO's, ESP, and numerology.

  10. Standards development status. Summary report

    International Nuclear Information System (INIS)

    1981-12-01

    The Standards Development Status Summary Report is designed for scheduling, monitoring, and controlling the process by which Regulatory Standards, Guides, Reports, Petitions, and Environmental Statements are written. It is a summary of the current schedule plans for development of the above products

  11. Experimental status of B decays

    International Nuclear Information System (INIS)

    Horwitz, N.

    1987-01-01

    This paper reviews the status of a number of current B-meson decay topics. Topics reviewed are: B reconstruction, penguins and rare decay modes, is there a charm deficit?, V ub /V bc , new limit on FCNC. Results are presented

  12. The status of 'standard' SUSY

    CERN Document Server

    Zwirner, F

    1992-01-01

    We summarize the present status of low-energy supersymmetry, exemplified by the Minimal Supersymmetric extension of the Standard Model (MSSM). We review the searches for Supersymmetric particles and supersymmetric Higgs bosons. We conclude with some comments on the open theoretical problems related to spontaneous supersymmetry breaking in the underlying fundamental theory.

  13. Status of the OPERA Experiment

    CERN Document Server

    Zimmermann, R.

    2006-01-01

    In this article the physics motivation and the detector design of the OPERA experiment will be reviewed. The construction status of the detector, which will be situated in the CNGS beam from CERN to the Gran Sasso laboratory, will be reported. A survey on the physics performance will be given and the physics plan in 2006 will be presented.

  14. Bibliography of Soviet Laser Developments, Number 87, January-February 1987

    Science.gov (United States)

    1987-12-29

    Physik (Leipzig) ATPLB Acta physica polonica . Series A AVMEB Avtometriya (CTC) CRABA Bolgarskaya akademiya nauk. Dokiady (formerly: Bulgarska... Physica status solidi (A). Applied Research (GDR) PSSBB Physica status solidi (B). Basic Research (GDR) PZTFD Zhurnal tekhnicheskoy fiziki. Pis’ma (CTC

  15. Population and status of women.

    Science.gov (United States)

    Selvaratnam, S

    1988-06-01

    It is difficult to determine the social status or rank of women, since no uniform indicators of status have been approved. Currently, in most Asian and Pacific countries, women make up the majority of illiterates (75% in South Asia; 70% in China), even in areas that have expanded their educational facilities. East and Southeast Asia have succeeded so far in their attempts to increase the enrollment ratios for women (90% female enrollment ratio as opposed to less than 50% in South Asia). Male-female roles seem to be entrenched in the society of all the countries. Women have benefited from an improvement in health care in East and Southeast Asia. In South Asia, female mortality is still very high. In most of the Asian and Pacific countries, female participation in the labor force is relatively low. However, this may be a misnomer, since the estimates do not include domestic workers that produce familial income. Women in the labor force seem to group into 4 major areas: professional and technical, clerical, service, and production work--all of which are usually low paying, low status jobs. Population growth in developing countries seems to have slowed the advancement of women toward greater gender equality by increasing the dependency burden and limiting social and material resources. High fertility rates among women correlate with an increase in illiteracy and a decrease in status improvement through education. Child bearing and home-making place heavy burdens on those women who marry young because of social pressures. Males are normally educated first in these larger families. The correlation of mortality conditions and female status is not currently clear. Rural-to-urban migration of the husband causes a weakening of the wife's status. Migration of some women to urban areas relieves social pressures and allows them to seek employment, but isolates others from a life with which they are familiar. Higher education of women seems to postpone marriage and child

  16. [Health status of elderly persons in Korea].

    Science.gov (United States)

    Choi, Y H; Kim, M S; Byon, Y S; Won, J S

    1990-12-01

    This Study was done to design and test an instrument to measure the health status of the elderly including physical, psychological and social dimensions. Data collection was done from July 18 to August 17, 1990. Subjects were 412 older persons in Korea. A convenience sample was used but the place of residence was stratified into large, medium and small city and rural areas. Participants located in Sudaemun-Gu, Mapo-Gu, and Kangnam-Gu, Seoul were interviewed by brained nursing students, and those in Chungju, Jonju, Chuncheon, and Jinju by professors of nursing colleges. Rural residents were interviewed by community health practitioners working in Kungsang-Buk-Do, Kyngsang-Nam-Do, Jonla Buk-Do, and Kyung Ki-Do. The tool developed for this study was a structured questionnaire based on previous literature and then tested for reliability and validity. This tool contained 20 physical health status items, 17 mental-emotional health status items and 38 social health status items. Physical health status items clustered in to six factors such as personal hygiene, activity, home management, digestive, sexual, sensory, and climatization functions. Mental-emotional health status items clustered into two factors, mental health and emotional health. Social health status items clustered into seven factors, grandparent, parent, spouse, friend, kinships, group member and religious role functions. Data analysis included percentage, average, S.D., t-test and ANOVA. The results of the analysis were as follows: 1. The tool measuring the health status of the elderly and developed for this research had a relatively high reliability indicated by a Cronbach = 0.97793. 2. Average score of the subjects physical health status was 4,054 in a 5 point likert scale, mental-emotional health status was 3.803, social health status was 2.939 and the total average was 3.521. The social status of the subjects was the lowest and the next was mental-emotional health status; physical health status was the

  17. Management of Autoimmune Status Epilepticus

    Directory of Open Access Journals (Sweden)

    Batool F. Kirmani

    2018-05-01

    Full Text Available Status epilepticus is a neurological emergency with increased morbidity and mortality. Urgent diagnosis and treatment are crucial to prevent irreversible brain damage. In this mini review, we will discuss the recent advances in the diagnosis and treatment of autoimmune status epilepticus (ASE, a rare form of the disorder encountered in the intensive care unit. ASE can be refractory to anticonvulsant therapy and the symptoms include subacute onset of short-term memory loss with rapidly progressive encephalopathy, psychiatric symptoms with unexplained new-onset seizures, imaging findings, CSF pleocytosis, and availability of antibody testing makes an earlier diagnosis of ASE possible. Neuroimmunomodulatory therapies are the mainstay in the treatment of ASE. The goal is to maximize the effectiveness of anticonvulsant agents and find an optimal combination of therapies while undergoing immunomodulatory therapy to reduce morbidity and mortality.

  18. HOMEOPATHY TODAY - EDUCATION AND STATUS

    Directory of Open Access Journals (Sweden)

    Snezana M Cupara

    2007-01-01

    Full Text Available Due to its encouaring results, classic homeopathy soon became very popular that a great number of homeopathic hospitals and educational institutions in Europe and America were founded at the end of the 19th century. However, historic events at the beinning of the 20th century diminished its use for the longer period of time. Since 1970, homoeopathy has been reviving in many countries of the world in different domains – educational institutions have appeared, it has been incorporated in many national health systems and there has been research development. Nowadays, homeopathy is recognised in all continents either as an independent or alternative (complementary medical system. Since status of homeopathy and possibilities for education have not been uniformed and standardized in the world, the aim of this article is to offer an abbreviated review on possibilities of education, status and history of homeopathy. The refer belong to developed countries, different continents and neighboring countries.

  19. Distributed systems status and control

    Science.gov (United States)

    Kreidler, David; Vickers, David

    1990-01-01

    Concepts are investigated for an automated status and control system for a distributed processing environment. System characteristics, data requirements for health assessment, data acquisition methods, system diagnosis methods and control methods were investigated in an attempt to determine the high-level requirements for a system which can be used to assess the health of a distributed processing system and implement control procedures to maintain an accepted level of health for the system. A potential concept for automated status and control includes the use of expert system techniques to assess the health of the system, detect and diagnose faults, and initiate or recommend actions to correct the faults. Therefore, this research included the investigation of methods by which expert systems were developed for real-time environments and distributed systems. The focus is on the features required by real-time expert systems and the tools available to develop real-time expert systems.

  20. 2016 Bioenergy Industry Status Report

    Energy Technology Data Exchange (ETDEWEB)

    Moriarty, Kristen L. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Milbrandt, Anelia R. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Warner, Ethan [National Renewable Energy Lab. (NREL), Golden, CO (United States); Lewis, John E. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Schwab, Amy A. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2018-03-03

    This report provides a snapshot of the bioenergy industry status at the end of 2016. The report compliments other annual market reports from the U.S. Department of Energy’s (DOE’s) Office of Energy Efficiency and Renewable Energy offices and is supported by DOE’s Bioenergy Technologies Office (BETO). The 2016 Bioenergy Industry Status Report focuses on past year data covering multiple dimensions of the bioenergy industry and does not attempt to make future market projections. The report provides a balanced and unbiased assessment of the industry and associated markets. It is openly available to the public and is intended to compliment International Energy Agency and industry reports with a focus on DOE stakeholder needs.

  1. Screening for Circulating Tumour Cells Allows Early Detection of Cancer and Monitoring of Treatment Effectiveness: An Observational Study

    Science.gov (United States)

    Ried, Karin; Eng, Peter; Sali, Avni

    2017-08-27

    Background: Circulating-Tumour-Cells (CTC) provide a blood biomarker for early carcinogenesis, cancer progression and treatment effectiveness. An increase in CTCs is associated with cancer progression, a CTC decrease with cancer containment or remission. Several technologies have been developed to identify CTC, including the validated Isolation-by-Size-of-Epithelial-Tumour (ISET, Rarecells) technology, combining blood filtration and microscopy using standard histo-pathological criteria. Methods: This observational study compared CTC count to cancer status and cancer risk, by monitoring treatment effectiveness in cancer patients and by screening for CTC in asymptomatic patients with risk factors, including family history of cancer. Results: Between Sept-2014 and Dec-2016 we undertook 600 CTC tests (542 patients), including 50% screening requests of patients without cancer diagnosis but with risk factors. CTC were detected in all cancer patients (n=277, 100%), and in half of the asymptomatic patients screened (50%, 132 out-of 265 patients). Follow-up tests including scans, scheduled within 1-10 months of positive CTC tests, found early cancerous lesions in 20% of screened patients. In 50% of male patients with CTC and normal PSA (prostate-specific-antigen) levels, PSMA-PET scans revealed increased uptake in the prostate, indicative of early prostate cancer. Other types of cancers detected by CTC screening and subsequent scans included early breast, ovarian, lung, or renal cancer. Patients with CTC were advised on integrative approaches including immune-stimulating and anti-carcinogenic nutritional therapies. CTC repeat tests were available in 10% of patients with detected CTC (40 outof 409 patients, n=98 CTC tests) to assess treatment effectiveness, suggesting nutritional therapies to be beneficial in reducing CTC count. Conclusions: CTC screening provided a highly sensitive biomarker for the early detection of cancer, with higher CTC counts being associated with

  2. Narcissism and the Pursuit of Status.

    Science.gov (United States)

    Zeigler-Hill, Virgil; Vrabel, Jennifer K; McCabe, Gillian A; Cosby, Cheryl A; Traeder, Caitlin K; Hobbs, Kelsey A; Southard, Ashton C

    2018-04-10

    The purpose of the present studies was to examine the connections that narcissistic admiration and narcissistic rivalry had with various aspects of status. Study 1 examined the associations that narcissism had with the motivation to seek status in a sample of 1,219 community members. Study 2 examined whether narcissism interacted with the status seeking motive to predict how individuals pursued status in a sample of 760 community members and college students. Study 3 used a daily diary approach to examine whether narcissism moderated the associations that daily perceptions of status and affiliation had with state self-esteem in 356 college students. Our results revealed that narcissistic admiration and narcissistic rivalry were somewhat similar in their desire for status but had divergent associations with other aspects of status (e.g., strategies employed to attain status, perceptions of status, reactions to perceived status). The results of the present studies suggest that narcissistic admiration is associated with an agentic orientation to the pursuit of status, whereas narcissistic rivalry is associated with an antagonistic orientation to the pursuit of status. Discussion focuses on the implications of these results for our understanding of the connections between narcissism and status. This article is protected by copyright. All rights reserved. © 2018 Wiley Periodicals, Inc.

  3. Status report on ILDG activities

    Energy Technology Data Exchange (ETDEWEB)

    Jansen, K. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC

    2006-09-15

    A status report about the International Lattice Data Grid (ILDG) is given. Different countries participating in the ILDG have created regional lattice data grid solutions that are implemented, working and used. The remaining task and the focus of present activities is the development of the interoperability of these regional grids. A first, successful step in this direction is a metadata catalogue service which is already working interoperable. (orig.)

  4. Status report on ILDG activities

    International Nuclear Information System (INIS)

    Jansen, K.

    2006-09-01

    A status report about the International Lattice Data Grid (ILDG) is given. Different countries participating in the ILDG have created regional lattice data grid solutions that are implemented, working and used. The remaining task and the focus of present activities is the development of the interoperability of these regional grids. A first, successful step in this direction is a metadata catalogue service which is already working interoperable. (orig.)

  5. Subcutaneous emphysema during status astmaticus

    International Nuclear Information System (INIS)

    Schwarz, E.

    1985-01-01

    Spontaneous subcutaneous accumulations of air in the soft parts of the thorax during an asthmatic crisis (status asthmaticus) are rarely seen. The pathomechanism of the phenomenon, which may lead to the formation of an emphysema of the soft parts via the pneumomediastinum, is discussed, and the possible complications which must be taken into account are pointed out. The value of radiological examination of the thorax in children suffering from asthma bronchiale, is explained briefly. (orig.) [de

  6. The status of perturbative QCD

    International Nuclear Information System (INIS)

    Ellis, R.K.

    1988-10-01

    The advances in perturbative QCD are reviewed. The status of determinations of the coupling constant α/sub S/ and the parton distribution functions is presented. New theoretical results on the spin dependent structure functions of the proton are also reviewed. The theoretical description of the production of vector bosons, jets and heavy quarks is outlined with special emphasis on new results. Expected rates for top quark production at hadronic colliders are presented. 111 refs., 8 figs

  7. Status of the MAGIC telescopes

    Energy Technology Data Exchange (ETDEWEB)

    Colin, Pierre; Carmona, Emiliano; Schweizer, Thomas; Sitarek, Julian [Max-Planck-Institut fuer Physik, Werner-Heisenberg Institut, Muenchen (Germany)

    2010-07-01

    MAGIC is a system of two 17-m Cherenkov telescopes located on La Palma (Canary islands),sensitive to gamma-rays above 30 GeV. It has been recently upgraded by a second telescope which strongly improves the sensitivity, particularly at low energy. Here we present the status of the MAGIC telescopes and an overview of the recent results obtained in single or stereoscopic mode. We also discuss the real performance of the new stereoscopic system based on Crab Nebula observations.

  8. Photoprotection and vitamin D status.

    Science.gov (United States)

    Springbett, Peter; Buglass, Surhi; Young, Antony R

    2010-11-03

    The adverse effects of solar ultraviolet radiation on the skin are well documented, especially in fair-skinned people. These can be ameliorated by photoprotection strategies advocated by many public health bodies and typically include sun avoidance, sunscreen use and clothing. The UVB waveband which is the main cause of all adverse effects investigated in the laboratory to date is also the waveband for vitamin D photosynthesis which is the only established benefit of solar exposure. This is especially important because solar UVB is the main source of vitamin D for most people. There is increasing evidence that vitamin D plays a much greater role in human health than was previously thought. This has given rise to concerns that photoprotection, especially sunscreen use, could adversely affect vitamin D status and human health. Furthermore, it is stated that people with heavily pigmented skins often have poor vitamin D status because of photoprotection by melanin. In this paper we review the effect of photoprotection strategies and pigmentation on vitamin D status. Clothing can clearly be very effective at inhibiting vitamin D synthesis. Sunscreens are effective in theory and some limited human studies support this. However, most studies show little or no effect and the most likely reason for this is that sunscreens have not been applied in the manner that was used to determine their labelled index of protection against sunburn. This could change in the future if public health campaigns and the sunscreen industry are successful in encouraging the public to apply sunscreens more liberally and/or use much higher levels of labelled protection. The role of melanin on vitamin D status is not clear and requires further investigation. Copyright © 2010. Published by Elsevier B.V.

  9. Happiness and Sexual Minority Status.

    Science.gov (United States)

    Thomeer, Mieke Beth; Reczek, Corinne

    2016-10-01

    We used logistic regression on nationally representative data (General Social Survey, N = 10,668 and N = 6680) to examine how sexual minority status related to happiness. We considered two central dimensions of sexual minority status-sexual behavior and sexual identity. We distinguished between same-sex, both-sex, and different-sex-oriented participants. Because individuals transition between sexual behavior categories over the life course (e.g., from both-sex partners to only same-sex partners) and changes in sexual minority status have theoretical associations with well-being, we also tested the associations of transitions with happiness. Results showed that identifying as bisexual, gay, or lesbian, having both male and female partners since age 18, or transitioning to only different-sex partners was negatively related to happiness. Those with only same-sex partners since age 18 or in the past 5 years had similar levels of happiness as those with only different-sex partners since age 18. Additional tests showed that the majority of these happiness differences became non-significant when economic and social resources were included, indicating that the lower happiness was a product of structural and societal forces. Our findings clearly and robustly underscored the importance of taking a multi-faceted approach to understanding sexuality and well-being, demonstrating that not all sexual minority groups experience disadvantaged happiness. Our study calls for more attention to positive aspects of well-being such as happiness in examinations of sexual minorities and suggests that positive psychology and other happiness subfields should consider the role of sexual minority status in shaping happiness.

  10. The WIMP Paradigm: Current Status

    International Nuclear Information System (INIS)

    Feng, Jonathan

    2011-01-01

    The WIMP paradigm is the glue that joins together much of the high energy and cosmic frontiers. It postulates that most of the matter in the Universe is made of weakly-interacting massive particles, with implications for a broad range of experiments and observations. I will review the WIMP paradigm's underlying motivations, its current status in view of rapid experimental progress on several fronts, and recent theoretical variations on the WIMP paradigm theme.

  11. Marital status, health and mortality.

    Science.gov (United States)

    Robards, James; Evandrou, Maria; Falkingham, Jane; Vlachantoni, Athina

    2012-12-01

    Marital status and living arrangements, along with changes in these in mid-life and older ages, have implications for an individual's health and mortality. Literature on health and mortality by marital status has consistently identified that unmarried individuals generally report poorer health and have a higher mortality risk than their married counterparts, with men being particularly affected in this respect. With evidence of increasing changes in partnership and living arrangements in older ages, with rising divorce amongst younger cohorts offsetting the lower risk of widowhood, it is important to consider the implications of such changes for health in later life. Within research which has examined changes in marital status and living arrangements in later life a key distinction has been between work using cross-sectional data and that which has used longitudinal data. In this context, two key debates have been the focus of research; firstly, research pointing to a possible selection of less healthy individuals into singlehood, separation or divorce, while the second debate relates to the extent to which an individual's transitions earlier in the life course in terms of marital status and living arrangements have a differential impact on their health and mortality compared with transitions over shorter time periods. After reviewing the relevant literature, this paper argues that in order to fully account for changes in living arrangements as a determinant of health and mortality transitions, future research will increasingly need to consider a longer perspective and take into account transitions in living arrangements throughout an individual's life course rather than simply focussing at one stage of the life course. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  12. Drug-induced status epilepticus.

    Science.gov (United States)

    Cock, Hannah R

    2015-08-01

    Drug-induced status epilepticus (SE) is a relatively uncommon phenomenon, probably accounting for less than 5% of all SE cases, although limitations in case ascertainment and establishing causation substantially weaken epidemiological estimates. Some antiepileptic drugs, particularly those with sodium channel or GABA(γ-aminobutyric acid)-ergic properties, frequently exacerbate seizures and may lead to SE if used inadvertently in generalized epilepsies or less frequently in other epilepsies. Tiagabine seems to have a particular propensity for triggering nonconvulsive SE sometimes in patients with no prior history of seizures. In therapeutic practice, SE is most commonly seen in association with antibiotics (cephalosporins, quinolones, and some others) and immunotherapies/chemotherapies, the latter often in the context of a reversible encephalopathy syndrome. Status epilepticus following accidental or intentional overdoses, particularly of antidepressants or other psychotropic medications, has also featured prominently in the literature: whilst there are sometimes fatal consequences, this is more commonly because of cardiorespiratory or metabolic complications than as a result of seizure activity. A high index of suspicion is required in identifying those at risk and in recognizing potential clues from the presentation, but even with a careful analysis of patient and drug factors, establishing causation can be difficult. In addition to eliminating the potential trigger, management should be as for SE in any other circumstances, with the exception that phenobarbitone is recommended as a second-line treatment for suspected toxicity-related SE where the risk of cardiovascular complications is higher anyways and may be exacerbated by phenytoin. There are also specific recommendations/antidotes in some situations. The outcome of drug-induced status epilepticus is mostly good when promptly identified and treated, though less so in the context of overdoses. This article is

  13. Status of 239Pu evaluations

    International Nuclear Information System (INIS)

    Kawano, Toshihiko; Talou, Patrick; Chadwick, Mark B.

    2014-01-01

    This paper summarises the current status of nuclear data evaluations for n+ 239 Pu. The nuclear data we address include fission, capture, scattering cross-sections, as well as the prompt fission neutron energy spectrum, which has large sensitivities to the criticality benchmark testing. The evaluated nuclear data files currently available for 239 Pu are compared, and the source of differences in the cross-sections are discussed. Some open questions on the statistical model calculations for deformed systems are also given. (authors)

  14. Renewables 2013. Global Status Report

    Energy Technology Data Exchange (ETDEWEB)

    Sawin, J. L. [and others

    2013-07-01

    Renewable energy markets, industries, and policy frameworks have evolved rapidly in recent years. The Renewables Global Status Report provides a comprehensive and timely overview of renewable energy market, industry, investment, and policy developments worldwide. It relies on the most recent data available, provided by many contributors and researchers from around the world, all of which is brought together by a multi-disciplinary authoring team. The report covers recent developments, current status, and key trends; by design, it does not provide analysis or forecasts. This latest Renewables Global Status Report saw: a shift in investment patterns that led to a global decrease in clean energy investment; continuing growth in installed capacity due to significant technology cost reductions and increased investment in developing countries; renewables progressively supplementing established electricity systems, demonstrating that the implementation of suitable policies can enable the successful integration of higher shares of variable renewables; and the emergence of integrated policy approaches that link energy efficiency measures with the implementation of renewable energy technologies.

  15. Nonconvulsive status epilepticus disguising as hepatic encephalopathy.

    Science.gov (United States)

    Jo, Yong Min; Lee, Sung Wook; Han, Sang Young; Baek, Yang Hyun; Ahn, Ji Hye; Choi, Won Jong; Lee, Ji Young; Kim, Sang Ho; Yoon, Byeol A

    2015-04-28

    Nonconvulsive status epilepticus has become an important issue in modern neurology and epileptology. This is based on difficulty in definitively elucidating the condition and its various clinical phenomena and on our inadequate insight into the intrinsic pathophysiological processes. Despite nonconvulsive status epilepticus being a situation that requires immediate treatment, this disorder may not be appreciated as the cause of mental status impairment. Although the pathophysiology of nonconvulsive status epilepticus remains unknown, this disorder is thought to lead to neuronal damage, so its identification and treatment are important. Nonconvulsive status epilepticus should be considered in the differential diagnosis of patients with liver cirrhosis presenting an altered mental status. We report a case of a 52-year-old male with liver cirrhosis presenting an altered mental status. He was initially diagnosed with hepatic encephalopathy but ultimately diagnosed with nonconvulsive status epilepticus by electroencephalogram.

  16. Nonconvulsive status epilepticus after electroconvulsive therapy

    DEFF Research Database (Denmark)

    Povlsen, Uffe Juul; Wildschiødtz, Gordon; Høgenhaven, Hans

    2003-01-01

    SUMMARY: We describe three cases of nonconvulsive status epilepticus induced by electroconvulsive therapy (ECT). Nonconvulsive status epilepticus is an important differential diagnosis in patients who develop prolonged confusion after ECT. The present cases exemplify the difficulty in defining...

  17. The Retinal Readout System: a status report A Status Report

    CERN Document Server

    Litke, A M

    1999-01-01

    The 'Retinal Readout System' is being developed to study the language the eye uses to send information about the visual world to the brain. Its architecture is based on that of silicon microstrip detectors. An array of 512 microscopic electrodes picks up the signals generated by the output neurons of live retinal tissue in response to a dynamic image focused on the input neurons. These signals are amplified, filtered and multiplexed by a set of eight custom-designed VLSI readout chips, and digitized and recorded by a data acquisition system. This report describes the goals, design, and status of the system. (author)

  18. Status and the evaluation of workplace deviance.

    Science.gov (United States)

    Bowles, Hannah Riley; Gelfand, Michele

    2010-01-01

    Bias in the evaluation of workplace misbehavior is hotly debated in courts and corporations, but it has received little empirical attention. Classic sociological literature suggests that deviance by lower-status actors will be evaluated more harshly than deviance by higher-status actors. However, more recent psychological literature suggests that discrimination in the evaluation of misbehavior may be moderated by the relative status of the evaluator because status influences both rule observance and attitudes toward social hierarchy. In Study 1, the psychological experience of higher status decreased rule observance and increased preferences for social hierarchy, as we theorized. In three subsequent experiments, we tested the hypothesis that higher-status evaluators would be more discriminating in their evaluations of workplace misbehavior, evaluating fellow higher-status deviants more leniently than lower-status deviants. Results supported the hypothesized interactive effect of evaluator status and target status on the evaluation of workplace deviance, when both achieved status characteristics (Studies 2a and 2b) and ascribed status characteristics (i.e., race and gender in Study 3) were manipulated.

  19. Does Status Inconsistency Matter for Marital Quality?

    Science.gov (United States)

    Gong, Min

    2007-01-01

    This study tests status inconsistency theory by examining the associations between wives' and husbands' relative statuses--that is, earnings, work-time, occupational, and educational inconsistencies--and marital quality and global happiness. The author asks three questions: (a) Is status inconsistency associated with marital quality and overall…

  20. Status Configurations, Military Service and Higher Education

    Science.gov (United States)

    Wang, Lin; Elder, Glen H., Jr.; Spence, Naomi J.

    2012-01-01

    The U.S. Armed Forces offer educational and training benefits as incentives for service. This study investigates the influence of status configurations on military enlistment and their link to greater educational opportunity. Three statuses (socioeconomic status of origin, cognitive ability and academic performance) have particular relevance for…

  1. 27 CFR 28.30 - Export status.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Export status. 28.30... Export status. (a) Distilled spirits and wines manufactured, produced, bottled in bottles packed in... such purposes are considered to be exported. Export status is not acquired until application on Form...

  2. Management of Status Epilepticus in Children

    Science.gov (United States)

    Smith, Douglas M.; McGinnis, Emily L.; Walleigh, Diana J.; Abend, Nicholas S.

    2016-01-01

    Status epilepticus is a common pediatric neurological emergency. Management includes prompt administration of appropriately selected anti-seizure medications, identification and treatment of seizure precipitant(s), as well as identification and management of associated systemic complications. This review discusses the definitions, classification, epidemiology and management of status epilepticus and refractory status epilepticus in children. PMID:27089373

  3. Management of Status Epilepticus in Children

    Directory of Open Access Journals (Sweden)

    Douglas M. Smith

    2016-04-01

    Full Text Available Status epilepticus is a common pediatric neurological emergency. Management includes prompt administration of appropriately selected anti-seizure medications, identification and treatment of seizure precipitant(s, as well as identification and management of associated systemic complications. This review discusses the definitions, classification, epidemiology and management of status epilepticus and refractory status epilepticus in children.

  4. “Experiences with disclosure of HIV-positive status to the infected child”: Perspectives of healthcare providers in Dar es Salaam, Tanzania

    Directory of Open Access Journals (Sweden)

    Adellah Sariah

    2016-10-01

    Full Text Available Abstract Background The specific age to which an HIV infected child can be disclosed to is stipulated to begin between ages 4 and 6 years. It has also been documented that before disclosure of HIV positive status to the infected child. Health care providers should consider children’s cognitive-developmental ability. However, observation and situation analysis show that, health care providers still feel uncomfortable disclosing the HIV positive status to the infected child. The aim of the study was to explore healthcare providers’ experiences in disclosure of HIV-positive status to the infected child. Methods A qualitative study involving 20 health care providers who attend HIV-positive children was conducted in September, 2014 in Dar es Salaam, Tanzania. Participants were selected from ten HIV care and treatment clinics (CTC by purposive sampling. An interview guide, translated into participants’ national language (Kiswahili was used during in-depth interviews. Sampling followed the principle of data saturation. The interviews focused on perspectives of health-care providers regarding their experience with paediatric HIV disclosure. Data from in-depth interviews were transcribed into text; data analysis followed qualitative content analysis. Results The results show how complex the process of disclosure to children living with HIV can be to healthcare providers. Confusion was noted among healthcare providers about their role and responsibility in the process of disclosing to the HIV infected child. This was reported to be largely due to unclear guidelines and lack of standardized training in paediatric HIV disclosure. Furthermore, healthcare providers were concerned about parental hesitancy to disclose early to the child due to lack of disclosure skills and fear of stigma. In order to improve the disclosure process in HIV infected children, healthcare providers recommended further standardized training on paediatric HIV disclosure with

  5. Preference for High Status Predicts Implicit Outgroup Bias among Children from Low-Status Groups

    Science.gov (United States)

    Newheiser, Anna-Kaisa; Dunham, Yarrow; Merrill, Anna; Hoosain, Leah; Olson, Kristina R.

    2014-01-01

    Whereas members of high-status racial groups show ingroup preference when attitudes are measured implicitly, members of low-status racial groups--both adults and children--typically show no bias, potentially reflecting awareness of the ingroup's low status. We hypothesized that when status differences are especially pronounced, children from…

  6. Estimated status 2006-2015

    International Nuclear Information System (INIS)

    2003-01-01

    According to article 6 of the French law from February 10, 2000 relative to the modernization and development of the electric public utility, the manager of the public power transportation grid (RTE) has to produce, at least every two years and under the control of the French government, a pluri-annual estimated status. Then, the energy ministry uses this status to prepare the pluri-annual planning of power production investments. The estimated status aims at establishing a medium- and long-term diagnosis of the balance between power supply and demand and at evaluating the new production capacity needs to ensure a durable security of power supplies. The hypotheses relative to the power consumption and to the evolution of the power production means and trades are presented in chapters 2 to 4. Chapter 5 details the methodology and modeling principles retained for the supply-demand balance simulations. Chapter 6 presents the probabilistic simulation results at the 2006, 2010 and 2015 prospects and indicates the volumes of reinforcement of the production parks which would warrant an acceptable level of security. Chapter 7 develops the critical problem of winter demand peaks and evokes the possibilities linked with demand reduction, market resources and use of the existing park. Finally, chapter 8 makes a synthesis of the technical conclusions and recalls the determining hypotheses that have been retained. The particular situations of western France, of the Mediterranean and Paris region, and of Corsica and overseas territories are examined in chapter 9. The simulation results for all consumption-production scenarios and the wind-power production data are presented in appendixes. (J.S.)

  7. Happiness and Sexual Minority Status

    Science.gov (United States)

    Thomeer, Mieke Beth; Reczek, Corinne

    2017-01-01

    We used logistic regression on nationally representative data (General Social Survey, N = 10,668 and N = 6,680) to examine how sexual minority status related to happiness. We considered two central dimensions of sexual minority status—sexual behavior and sexual identity. We distinguished between same-sex, both-sex, and different-sex oriented participants. Because individuals transition between sexual behavior categories over the life course (e.g., from both-sex partners to only same-sex partners) and changes in sexual minority status have theoretical associations with well-being, we also tested the effects of transitions on happiness. Results showed that identifying as bisexual, gay, or lesbian, having both male and female partners since age 18, or transitioning to only different-sex partners was negatively related to happiness. Those with only same-sex partners since age 18 or in the past five years had similar levels of happiness as those with only different-sex partners since age 18. Additional tests showed that the majority of these happiness differences became non-significant when economic and social resources were included, indicating that the lower happiness was a product of structural and societal forces. Our findings clearly and robustly underscored the importance of taking a multi-faceted approach to understanding sexuality and well-being, demonstrating that not all sexual minority groups experience disadvantaged happiness. Our study calls for more attention to positive aspects of well-being such as happiness in examinations of sexual minorities and suggests that positive psychology and other happiness subfields should consider the role of sexual minority status in shaping happiness. PMID:27102605

  8. Reducing status quo bias in choice experiments

    DEFF Research Database (Denmark)

    Bonnichsen, Ole; Ladenburg, Jacob

    In stated preference literature, the tendency to choose the alternative representing the status quo situation seems to exceed real life status quo effects. Accordingly, status quo bias can be a problem. In Choice Experiments, status quo bias is found to be strongly correlated with protest attitudes...... toward the cost attribute. If economic values are to be elicited, this problem is difficult to remedy. In a split sample framework we test a novel ex-ante entreaty aimed specifically at the cost attribute and find that it effectively reduces status quo bias and improves the internal validity...

  9. Renewables 2005. Global status report

    International Nuclear Information System (INIS)

    2005-01-01

    This report provides an overview of the status of renewable energy worldwide in 2005. It covers markets, investments, industries, policies, and rural (off-grid) renewable energy in developing countries. By design, the report does not provide analysis, recommendations, or conclusions. An extensive research and review process over several months involving more than 100 researchers and contributors has kept inaccuracies to a minimum. REN21 sees this report as the beginning of an active exchange of views and information. This report reveals some surprising facts about renewable energy, many reflecting strong growth trends and increasing significance relative to conventional energy. (au)

  10. Renewables 2007 - Global status report

    International Nuclear Information System (INIS)

    Martinot, Eric; Mastny, Lisa; Rosbotham, Lyle; Suding, Paul; Sonntag-O'Brien, Virginia; Lempp, Philippe

    2007-01-01

    In 2007, more than $100 billion was invested in new renewable energy capacity, manufacturing plants, and research and development-a true global milestone. Yet perceptions lag behind the reality of renewable energy because change has been so rapid in recent years. This report captures that reality and provides an overview of the status of renewable energy worldwide in 2007. The report covers trends in markets, investments, industries, policies, and rural (off-grid) renewable energy. (By design, the report does not provide analysis, discuss current issues, or forecast the future.) Many of the trends reflect increasing significance relative to conventional energy

  11. Renewables 2005. Global status report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    This report provides an overview of the status of renewable energy worldwide in 2005. It covers markets, investments, industries, policies, and rural (off-grid) renewable energy in developing countries. By design, the report does not provide analysis, recommendations, or conclusions. An extensive research and review process over several months involving more than 100 researchers and contributors has kept inaccuracies to a minimum. REN21 sees this report as the beginning of an active exchange of views and information. This report reveals some surprising facts about renewable energy, many reflecting strong growth trends and increasing significance relative to conventional energy. (au)

  12. Renewables 2005 - Global status report

    International Nuclear Information System (INIS)

    Martinot, Eric

    2005-01-01

    This report provides an overview of the status of renewable energy worldwide in 2005. It covers markets, investments, industries, policies, and rural (off-grid) renewable energy in developing countries. By design, the report does not provide analysis, recommendations, or conclusions. An extensive research and review process over several months involving more than 100 researchers and contributors has kept inaccuracies to a minimum. REN21 sees this report as the beginning of an active exchange of views and information. This report reveals some surprising facts about renewable energy, many reflecting strong growth trends and increasing significance relative to conventional energy

  13. GEO600: status and plans

    International Nuclear Information System (INIS)

    Willke, B

    2007-01-01

    The GEO600 gravitational wave detector located near Hannover in Germany is one of the four detectors of the LIGO Scientific Collaboration (LSC). For almost the entire year of 2006, GEO600 participated in the S5 science run of the LSC. Overall an equivalent of about 270 days of science data with an average peak sensitivity of better than 3 x 10 -22 Hz -1/2 have been acquired so far. In this paper, we describe the status of the GEO600 project during the period between January 2006 and February 2007. In addition, plans for the near-term and medium-term future are discussed

  14. Status of the VIRGO experiment

    International Nuclear Information System (INIS)

    Yvert, M.

    1994-07-01

    The VIRGO experiment was approved in September 1993. The goal of the French-Italian collaboration is to detect Gravitational Waves using a 3 km arm-length Michelson interferometer. The construction of this detector, which will be installed in Pisa, is under way. The experiment is planned to take data, in a large bandwidth (10Hz-10kHz), at the beginning of year 2000 with nominal sensitivity close to h=3x10 -23 /√Hz. The motivations, detection principle, main sources of noise and status of the experiment are presented. (author). 14 refs., 4 figs

  15. Status of the VIRGO experiment

    International Nuclear Information System (INIS)

    Caron, B.; Dominjon, A.; Marion, F.

    1995-01-01

    The VIRGO experiment was approved in September 1993. The goal of the French-Italian collaboration is to detect gravitational waves using a 3 km arm-length Michelson interferometer. The construction of this detector, which will be installed in Pisa, is under way. The experiment is planned to take data, in a large bandwidth (10 Hz-10 kHz), at the beginning of the year 2000 with nominal sensitivity close to h=3x10 -23 /√(Hz). The motivations, detection principle, main sources of noise and status of the experiment are presented. (orig.)

  16. Taxonomic status of Anastrepha fraterculus

    International Nuclear Information System (INIS)

    Steck, G.J.

    1999-01-01

    There has long been speculation that nominal Anastrepha fraterculus comprises more than a single biological species. Herein is a review of data supporting the hypothesis that multiple cryptic species are present. Evidence includes unusual variation in pest status, morphology, karyotypes, isozymes, mitochondrial DNA and cuticular hydrocarbon. The data strongly support the notion of multiple cryptic species. However, it is not yet possible to state how many species may be involved or to delineate them by diagnostic morphology, distribution, host plants or behavior. A combination of methodologies will be needed to resolve the complex. (author)

  17. Product Operations Status Summary Metrics

    Science.gov (United States)

    Takagi, Atsuya; Toole, Nicholas

    2010-01-01

    The Product Operations Status Summary Metrics (POSSUM) computer program provides a readable view into the state of the Phoenix Operations Product Generation Subsystem (OPGS) data pipeline. POSSUM provides a user interface that can search the data store, collect product metadata, and display the results in an easily-readable layout. It was designed with flexibility in mind for support in future missions. Flexibility over various data store hierarchies is provided through the disk-searching facilities of Marsviewer. This is a proven program that has been in operational use since the first day of the Phoenix mission.

  18. Renewables 2012. Global Status Report

    Energy Technology Data Exchange (ETDEWEB)

    Sawin, J. L. [and others

    2012-08-15

    Renewable energy markets and policy frameworks have evolved rapidly in recent years. This report provides a comprehensive and timely overview of renewable energy market, industry, investment, and policy developments worldwide. It relies on the most recent data available, provided by a network of more than 400 contributors and researchers from around the world, all of which is brought together by a multi-disciplinary authoring team. The report covers recent developments, current status, and key trends; by design, it does not provide analysis or forecast the future.

  19. MIRAGE: system overview and status

    Science.gov (United States)

    Robinson, Richard M.; Oleson, Jim; Rubin, Lane; McHugh, Stephen W.

    2000-07-01

    Santa Barbara Infrared's (SBIR) MIRAGE (Multispectral InfraRed Animation Generation Equipment) is a state-of-the-art dynamic infrared scene projector system. Imagery from the first MIRAGE system was presented to the scene simulation community during last year's SPIE AeroSense 99 Symposium. Since that time, SBIR has delivered five MIRAGE systems. This paper will provide an overview of the MIRAGE system and discuss the current status of the MIRAGE. Included is an update of system hardware, and the current configuration. Proposed upgrades to this configuration and options will be discussed. Updates on the latest installations, applications and measured data will also be presented.

  20. Status of the experiment ASYEOS

    Energy Technology Data Exchange (ETDEWEB)

    Kupny, Sebastian [GSI Helmholtzzentrum GmbH Darmstadt (Germany); Collaboration: ASYEOS-Collaboration

    2012-07-01

    Neutron-proton squeeze-out is predicted to provide quantitative information on the symmetry term of the nuclear Equation of State at supra-saturation densities. Hence we designed an experiment consisting out of the CHIMERA charged particle detector for impact parameter determination and reaction plane reconstruction, the LAND neutron detector to measure neutron and proton squeeze-out and a Triple Telescope Array to identify light fragments. Measurements of 197Au+197Au, 96Ru+96Ru and 96Zr+96Zr collisions at 400 A MeV have been accomplished in May 2011 at the GSI facility. Current status of the analysis, first results and future plans are presented.

  1. LHC Status and Upgrade Challenges

    Science.gov (United States)

    Smith, Jeffrey

    2009-11-01

    The Large Hadron Collider has had a trying start-up and a challenging operational future lays ahead. Critical to the machine's performance is controlling a beam of particles whose stored energy is equivalent to 80 kg of TNT. Unavoidable beam losses result in energy deposition throughout the machine and without adequate protection this power would result in quenching of the superconducting magnets. A brief overview of the machine layout and principles of operation will be reviewed including a summary of the September 2008 accident. The current status of the LHC, startup schedule and upgrade options to achieve the target luminosity will be presented.

  2. Network management, status and directions

    International Nuclear Information System (INIS)

    Cottrell, R.L.A.; Streater, T.C.

    1992-09-01

    It has been said that the ''network is the system''. This implies providing levels of service, reliability, predictability and availability that are commensurate with or better than those that individual computers provide today. To provide this requires integrated network management for interconnected networks of heterogeneous devices covering both the local campus and across the world and spanning many administrative domains. This talk will review the status of existing tools to address management for networks. It draws on experience from both within and outside the HEP community

  3. Experimental status of unified theories

    International Nuclear Information System (INIS)

    Bilen'kij, S.M.

    1979-01-01

    A standard SU(2)xU(1) theory is discussed. It is based on an assumption that the left components of fields form doublets, and the rignt ones - singlets. From the weak interaction lagrangian an expression is obtained for the effective hamiltonian describing neutrino-lepton processes. The results of discussing the experimental status of the unified theories of weak and electromagnetic interactions are in agreement with the simplest version of the unified theories - the Weinberg-Salam theory. It has been noted that the accuracy of the experiments (not exceeding 20%) is insufficient and no information is available on diagonal terms of the hamiltonian

  4. Pathological buying and partnership status.

    Science.gov (United States)

    Müller, Astrid; de Zwaan, Martina; Mitchell, James E; Zimmermann, Tanja

    2016-05-30

    This pilot study investigated the partnership status and the level of pathological buying (PB) in 157 female patients with PB and 1153 women from a German population-based sample. Slightly more than half of both samples were currently living with a partner. The results suggest a protective effect of being in a couple relationship in the representative sample. In contrast, having a partner was not related to the severity of PB among patients. Future studies should address the question of whether the characteristics and quality of partnership have an impact on the severity and course of PB, and vice versa. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  5. Status of LLNL granite projects

    International Nuclear Information System (INIS)

    Ramspott, L.D.

    1980-01-01

    The status of LLNL Projects dealing with nuclear waste disposal in granitic rocks is reviewed. This review covers work done subsequent to the June 1979 Workshop on Thermomechanical Modeling for a Hardrock Waste Repository and is prepared for the July 1980 Workshop on Thermomechanical-Hydrochemical Modeling for a Hardrock Waste Repository. Topics reviewed include laboratory determination of thermal, mechanical, and transport properties of rocks at conditions simulating a deep geologic repository, and field testing at the Climax granitic stock at the USDOE Nevada Test Site

  6. Status of food irradiation worldwide

    International Nuclear Information System (INIS)

    Loaharanu, P.

    1992-01-01

    The past four decades have witnessed the steady development of food irradiation technology - from laboratory-scale research to full-scale commercial application. The present status of this technology, approval for processing food items in 37 countries and commerical use of irradiated food in 24 countries, will be discussed. The trend in the use of irradiation to overcome certain trade barriers such as quarantine and hygiene will be presented. Emphasis will be made on the use of irradiation as an alternative to chemical treatments of food. (orig.) [de

  7. Lattice QCD: Status and Prospect

    International Nuclear Information System (INIS)

    Ukawa, Akira

    2006-01-01

    A brief review is given of the current status and near-future prospect of lattice QCD studies of the Standard Model. After summarizing a bit of history, we describe current attempts toward inclusion of dynamical up, down and strange quarks. Recent results on the light hadron mass spectrum as well as those on the heavy quark quantities are described. Recent work on lattice pentaquark search is summarized. We touch upon the PACS-CS Project for building our next machine for lattice QCD, and conclude with a summary of computer situation and the physics possibilities over the next several years

  8. Current Status of HPV Vaccines

    Science.gov (United States)

    Ma, Barbara; Roden, Richard; Wu, T.C.

    2010-01-01

    Cervical cancer is the second largest cause of cancer deaths in women worldwide, with ~500,000 diagnoses and 274,000 deaths annually. It remains a significant source of morbidity and mortality despite effective screening tools and treatments for its precursor high-grade cervical intraepithelial neoplasia (CIN). Increased understanding of cervical pathogenesis has led to the identification of human papillomavirus (HPV) as the etiological agent for cervical cancer and the development of preventive and therapeutic vaccines targeting HPV antigens for the control of cervical cancer. Herein, we discuss the current status of HPV vaccines. PMID:20677402

  9. Dark Matter Detection: Current Status

    International Nuclear Information System (INIS)

    Akerib, Daniel S.

    2011-01-01

    Overwhelming observational evidence indicates that most of the matter in the Universe consists of non-baryonic dark matter. One possibility is that the dark matter is Weakly-Interacting Massive Particles (WIMPs) that were produced in the early Universe. These relics could comprise the Milky Way's dark halo and provide evidence for new particle physics, such as Supersymmetry. This talk focuses on the status of current efforts to detect dark matter by testing the hypothesis that WIMPs exist in the galactic halo. WIMP searches have begun to explore the region of parameter space where SUSY particles could provide dark matter candidates.

  10. Health status among elderly Hungarians and Americans.

    Science.gov (United States)

    Buss, T F; Beres, C; Hofstetter, C R; Pomidor, A

    1994-07-01

    Selected health status data for elderly populations from similar industrial cities-Youngstown, Ohio, USA, and Debrecen, Hungary-were compared. Because of their impoverished health care system, unregulated heavily industrialized society, and unhealthful life-styles Hungarians were hypothesized to have poorer health status than Americans, even after taking into account demographic mediating factors. The study provides a health status baseline for elderly Hungarians shortly after communism's fall in 1989-1990 and shows how great a gap exists between Hungarian health status and that in the West. Hungarians were in much poorer health as measured by functional status, symptomatology, medical condition, depression, and subjective health status. Distinctions persisted when controlling for gender, age, and education. Poverty-level (and income) did not explain health status differences. The paper concludes that Hungary should pay more attention to health promotion, prevention, and primary care, as well as to reforming patient management in hospitals, nursing homes, and home care programs.

  11. Status Configurations, Military Service and Higher Education.

    Science.gov (United States)

    Wang, Lin; Elder, Glen H; Spence, Naomi J

    2012-12-01

    The U.S. Armed Forces offer educational and training benefits as incentives for service. This study investigates the influence of status configurations on military enlistment and their link to greater educational opportunity. Three statuses (socioeconomic status of origin, cognitive ability and academic performance) have particular relevance for life course options. We hypothesize that young men with inconsistent statuses are more likely to enlist than men with consistent status profiles, and that military service improves access to college for certain configurations. Analyses of the National Longitudinal Study of Adolescent Health (Add Health) show (1. that several status configurations markedly increased the likelihood of military enlistment and (2. within status configurations, recruits were generally more likely to enroll in higher education than nonveterans, with associate degrees being more likely.

  12. Status Configurations, Military Service and Higher Education

    Science.gov (United States)

    Wang, Lin; Elder, Glen H.; Spence, Naomi J.

    2012-01-01

    The U.S. Armed Forces offer educational and training benefits as incentives for service. This study investigates the influence of status configurations on military enlistment and their link to greater educational opportunity. Three statuses (socioeconomic status of origin, cognitive ability and academic performance) have particular relevance for life course options. We hypothesize that young men with inconsistent statuses are more likely to enlist than men with consistent status profiles, and that military service improves access to college for certain configurations. Analyses of the National Longitudinal Study of Adolescent Health (Add Health) show (1. that several status configurations markedly increased the likelihood of military enlistment and (2. within status configurations, recruits were generally more likely to enroll in higher education than nonveterans, with associate degrees being more likely. PMID:24511161

  13. Subjective social status and health.

    Science.gov (United States)

    Euteneuer, Frank

    2014-09-01

    Subjective social status (SSS) predicts health outcomes above and beyond traditional objective measures of social status, such as education, income and occupation. This review summarizes and integrates recent findings on SSS and health. Current studies corroborate associations between low SSS and poor health indicators by extending previous findings to further populations and biological risk factors, providing meta-analytic evidence for adolescents and by demonstrating that negative affect may not confound associations between SSS and self-rated health. Recent findings also highlight the relevance of SSS changes (e.g. SSS loss in immigrants) and the need to consider cultural/ethnical differences in psychological mediators and associations between SSS and health. SSS is a comprehensive measure of one's social position that is related to several poor health outcomes and risk factors for disease. Future investigation, particularly prospective studies, should extend research on SSS and health to further countries/ethnic groups, also considering additional psychological and biological mediators and dynamic aspects of SSS. Recently developed experimental approaches to manipulate SSS may also be promising.

  14. Food and families' socioeconomic status.

    Science.gov (United States)

    Kinsey, J D

    1994-09-01

    This paper explores the relationship between food expenditures and consumption patterns and families' socioeconomic status in the United States. Three themes follow through the paper. One is that as income rises over time and across socioeconomic groups, a smaller percent of that income is spent of food. Simultaneously, a larger percent of the food dollar buys services and food preparation moves farther away from the home. Second, characteristics of people like age and ethnicity contribute to diversity in food consumption but labor force participation by women has led the trend in away-from-home-food preparation. New scientific information and technology have changed attitudes about nutrition and food safety and their linkages to health. Finally, the continuous introduction of affordable new foods into the diet and culture of families in all socioeconomic groups has been a quiet evolution. Trying to differentiate socioeconomic groups in the United States by their food and nutritional status is almost a nonstory except for fascinating intragroup diversities that change rapidly in the postmodern society.

  15. Worldwide status of HTR development

    International Nuclear Information System (INIS)

    1978-06-01

    The International Atomic Energy Agency convened a technical committee meeting on high temperature reactors (HTRs) from 12-14 Dec. 1977 at Agency Headquarters to provide a forum for the exchange of information on the status of HTR development programmes and to receive advice on the Agency programme in this field. The continuing high level of international interest in HTRs was evidenced by the participation from 11 countries and 2 organizations: Austria, Belgium, France, Federal Republic of Germany, Japan, Netherlands, Poland, Switzerland, Union of Soviet Socialist Republics, United Kingdom of Great Britain, United States of America, Commission of the European Communities, and the OECD Nuclear Energy Agency. In order to promote the continuing exchange of technical information through the offices of the IAEA, a recommendation was made that the Agency establish a standing International Working Group on High Temperature Reactors (IWGHTR). This recommendation is being implemented in 1978. Considerable information on recent progress in HTR development was present at the technical committee meeting in technical reports and in progress reports on HTR development programmes. Since this material will not be published, this summary report on the worldwide status of HTR development at the beginning of 1978 has been prepared, based primarily on information presented at the December 1977 meeting

  16. renewables 2011 - Global status report

    International Nuclear Information System (INIS)

    Sawin, Janet L.; Martinot, Eric; Barnes, Douglas; Martinot, Eric; McCrone, Angus; Roussell, Jodie; Sawin, Janet L.; Sims, Ralph; Sonntag-O'Brien, Virginia; Adib, Rana; Skeen, Jonathan; Musolino, Evan; Riahi, Lily; Mastny, Lisa

    2011-01-01

    Changes in renewable energy markets, investments, industries, and policies have been so rapid in recent years that perceptions of the status of renewable energy can lag years behind the reality. This report captures that reality and provides a unique overview of renewable energy worldwide as of early 2011. The report covers both current status and key trends; by design, it does not provide analysis or forecast the future. Global energy consumption rebounded in 2010 after an overall downturn in 2009. Renewable energy, which experienced no downturn in 2009, continued to grow strongly in all end-use sectors - power, heat and transport - and supplied an estimated 16% of global final energy consumption. Renewable energy accounted for approximately half of the estimated 194 gigawatts (GW) of new electric capacity added globally during the year. Renewables delivered close to 20% of global electricity supply in 2010, and by early 2011 they comprised one quarter of global power capacity from all sources. In several countries, renewables represent a rapidly growing share of total energy supply, including heat and transport

  17. Status of the CBM experiment

    Directory of Open Access Journals (Sweden)

    Heuser Johann M.

    2015-01-01

    Full Text Available The Compressed Baryonic Matter (CBM experiment at the Facility for Anti-Proton and Ion Research (FAIR will explore the phase diagram of strongly interacting matter at highest net baryon densities and moderate temperatures. The CBM physics program will be started with beams delivered by the SIS 100 synchrotron, providing energies from 2 to 11 GeV/nucleon for heavy nuclei, up to 14 GeV/nucleon for light nuclei, and 29 GeV for protons. The highest net baryon densities will be explored with ion beams up to 45 GeV/nucleon energy delivered by SIS 300 in the next stage of FAIR. Collision rates up to 107 per second are required to produce very rare probes with unprecedented statistics in this energy range. Their signatures are complex. These conditions call for detector systems designed to meet the extreme requirements in terms of rate capability, momentum and spatial resolution, and a novel DAQ and trigger concept which is not limited by latency but by throughput. The article discusses the development status of the CBM sub-systems for charged particle tracking, vertex detection, electron/muon identification, hadron/time-of-flight measurement, electromagnetic and zero-degree calorimetry, in terms of prototypes and expected physics performance. The concept and development status of CBM’s central detector, the Silicon Tracking System STS are presented in somewhat more detail.

  18. Repository development status in Spain

    Energy Technology Data Exchange (ETDEWEB)

    Rodriguez Beceiro, Alvaro; Zuloaga, Pablo [ENRESA (Spain)

    2009-06-15

    The paper describes the status of repository development for the different waste categories. Low and Intermediate Waste Disposal facility of El Cabril was commissioned in 1992 and is in normal operation. The major modifications and activities during the last years are the adaptation to waste streams not initially foreseen such as some decommissioning waste or waste from steel industry, and the improvement of its performance assessment, supported by a R and D and refined models. As part of this facility, a new disposal facility specifically intended for very low activity waste has been constructed and commissioned in July 2008. Its design is based on the European Directive for hazardous waste disposal. National policy for Nuclear Spent Fuel and High-Level waste is focused on the development of a centralized storage facility of the vault type, whose site location would be selected through a volunteering process. Meanwhile, with the aim of solving specific problems, three individual storage facilities are in different status at reactor sites. Research on final solution, including some repository aspects as well as separation and transmutation are being carried out in accordance to ENRESA's R and D program. ENRESA has developed conceptual designs for non site specific repositories, both in granite and clay, and has carried out their corresponding performance assessment exercises. (authors)

  19. Global status of hydrogen research

    Energy Technology Data Exchange (ETDEWEB)

    Lakeman, J.B.; Browning, D.J.

    2001-07-01

    This report surveys the global status of hydrogen research and identifies technological barriers to the implementation of a global hydrogen economy. It is concluded that there will be a 30 year transition phase to the full implementation of the hydrogen economy. In this period, hydrogen will be largely produced by the reformation of hydrocarbons, particularly methane. It will be necessary to ensure that any carbonaceous oxides (and other unwanted species) formed as by-products will be trapped and not released into the atmosphere. Following the transition phase, hydrogen should be largely produced from renewable energy sources using some form of water cracking, largely electrolysis. Target performances and costs are identified for key technologies. The status of hydrogen research in the UK is reviews and it is concluded that the UK does not have a strategy for the adoption of the hydrogen economy, nor does it have a coherent and co-ordinated research and development strategy addressing barriers to the hydrogen economy. Despite this fact, because of the long transition phase, it is still possible for the UK to formulate a coherent strategy and make a significant contribution to the global implementation of the hydrogen economy, as there are still unresolved technology issues. The report concludes with a number of recommendations. (Author)

  20. MENA Renewables Status Report 2013

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-06-15

    The MENA Renewables Status Report is an outcome of ADIREC, the Abu Dhabi International Renewable Energy Conference. The report provides a status overview of renewable energy markets, industry, policy and investment trends in the region, drawing on the most recent data available. It is produced in cooperation with over 50 contributors and researchers in the region and reveals massive growth in the renewable energy markets of the Middle East and North Africa (MENA). Regional investment topped US$2.9 billion in 2012, up 40% from 2011 and 650% from 2004. With over 100 projects under development, the region could see a 450% increase in non-hydro renewable energy generating capacity in the next few years. For the report, the 21 MENA countries were clustered into two sub-groups: Net Oil-Exporting Countries (NOEC) -- Algeria, Bahrain, Egypt, Iran, Iraq, Kuwait, Libya, Oman, Qatar, Saudi Arabia, Syria, United Arab Emirates, and Yemen; and Net Oil-Importing Countries (NOIC) -- Djibouti, Israel, Jordan, Lebanon, Malta, Morocco, Palestine, and Tunisia.

  1. Periodontal Status of Postmenopausal Women

    Directory of Open Access Journals (Sweden)

    Timur V. Melkumyan

    2014-06-01

    Full Text Available The objective of this study was to compare the periodontal status in postmenopausal women with osteopenia and osteoporosis. Material and Methods: We examined 43 postmenopausal women aged from 55 to 74 years. Material assessment of bones in every patient was performed by means of dual energy X-ray absorptiometry (DXA from two points on the skeleton – part of the femur neck and between the first and fourth lumbar vertebrae. A lipid blood test was done for patients of both groups. All patients were divided into two groups (the 1st with osteopenia, and the 2nd with osteoporosis. All patients were subjected to an oral clinical examination: the periodontal examination was composed of Plaque Index (PI, Pocket Score (PS, and Papillary Bleeding Index (PBI. X-ray analysis was performed for every patient. Results: The results of the clinical periodontal examination demonstrated that the mean PBI in patients in the 1st group had no significant differences from the PBI in patients in the 2nd group. PI value and PS findings in patients with general osteoporosis also had no statistical differences from the same parameters in patients with osteopenia. Conclusion: Under the circumstances of these patients’ characteristics and within the limits of the present study, we concluded that there is no significant difference in the periodontal status of postmenopausal women with systemic osteopenia and with osteoporosis.

  2. Treatment of Convulsive Status Epilepticus.

    Science.gov (United States)

    Grover, Eric H; Nazzal, Yara; Hirsch, Lawrence J

    2016-03-01

    Convulsive status epilepticus (CSE) is a medical emergency with an associated high mortality and morbidity. It is defined as a convulsive seizure lasting more than 5 min or consecutive seizures without recovery of consciousness. Successful management of CSE depends on rapid administration of adequate doses of anti-epileptic drugs (AEDs). The exact choice of AED is less important than rapid treatment and early consideration of reversible etiologies. Current guidelines recommend the use of benzodiazepines (BNZ) as first-line treatment in CSE. Midazolam is effective and safe in the pre-hospital or home setting when administered intramuscularly (best evidence), buccally, or nasally (the latter two possibly faster acting than intramuscular (IM) but with lower levels of evidence). Regular use of home rescue medications such as nasal/buccal midazolam by patients and caregivers for prolonged seizures and seizure clusters may prevent SE, prevent emergency room visits, improve quality of life, and lower health care costs. Traditionally, phenytoin is the preferred second-line agent in treating CSE, but it is limited by hypotension, potential arrhythmias, allergies, drug interactions, and problems from extravasation. Intravenous valproate is an effective and safe alternative to phenytoin. Valproate is loaded intravenously rapidly and more safely than phenytoin, has broad-spectrum efficacy, and fewer acute side effects. Levetiracetam and lacosamide are well tolerated intravenous (IV) AEDs with fewer interactions, allergies, and contraindications, making them potentially attractive as second- or third-line agents in treating CSE. However, data are limited on their efficacy in CSE. Ketamine is probably effective in treating refractory CSE (RCSE), and may warrant earlier use; this requires further study. CSE should be treated aggressively and quickly, with confirmation of treatment success with epileptiform electroencephalographic (EEG), as a transition to non-convulsive status

  3. Relationship of HIV Reservoir Characteristics with Immune Status and Viral Rebound Kinetics in an HIV Therapeutic Vaccine Study

    Science.gov (United States)

    Li, Jonathan Z.; Heisey, Andrea; Ahmed, Hayat; Wang, Hongying; Zheng, Lu; Carrington, Mary; Wrin, Terri; Schooley, Robert T.; Lederman, Michael M.; Kuritzkes, Daniel R.

    2014-01-01

    Objectives To evaluate the impact of therapeutic HIV vaccination on the HIV reservoir, and assess the relationship of the viral reservoir with HIV-specific immune status and viral rebound kinetics. Design Retrospective analysis of ACTG A5197, a randomized, placebo-controlled trial of a therapeutic rAd5 HIV-1 gag vaccine. Methods Participants received vaccine/placebo at weeks 0, 4, and 26 prior to a 16-week analytic treatment interruption (ATI) at week 38. Cell-associated HIV-1 RNA and DNA (CA-RNA and CA-DNA) and HIV-1 residual viremia (RV) were quantified at weeks 0, 8, and 38. HIV-specific CD4+/CD8+ activity were assessed by an intracellular cytokine staining assay. Results At study entry, CA-RNA and CA-DNA levels were correlated inversely with the numbers of HIV-specific CD4+ interferon-γ-producing cells (CA-RNA: r = −0.23, P=0.03 and CA-DNA: r = −0.28, P<0.01, N=93). Therapeutic HIV vaccination induced HIV-specific CD4+ activity, but did not significantly affect levels of CA-RNA or CA-DNA. Vaccine recipients with undetectable RV at week 8 had higher frequencies of HIV-specific CD4+ and CD8+ interferon-γ-producing cells (undetectable versus detectable RV: 277 versus 161 CD4+ cells/106 lymphocytes, P=0.03 and 1326 versus 669 CD8+ cells/106 lymphocytes, P=0.04). Pre-ATI CA-RNA and CA-DNA were associated with post-ATI plasma HIV set point (CA-RNA: r = 0.51, P<0.01 and CA-DNA: r = 0.47, P<0.01). Conclusions Vaccine-induced T-cell responses were associated with a modest transient effect on RV, but more potent immune responses and/or combination treatment with latency-reversing agents are needed to reduce the HIV reservoir. HIV reservoir measures may act as biomarkers of post-ATI viral rebound kinetics. PMID:25254301

  4. Upgrade programs. Status and prospective

    International Nuclear Information System (INIS)

    Loyer, F.

    1998-01-01

    Arguments for launching a renovation program for GANIL system, taking into account aging and wear, are analyzed. A statistics of failures related to vacuum systems, power supplies, electronics, cooling systems, beam dumps and other equipment is given. The renovation program is targeted to: replacement of obsolete components, introduction of advanced systems of failure diagnosis, augmentation of performances of the new regulating and control system and improvement in the performance characteristics of certain fundamental equipment. The first results and to date status of the program development is reported. Mentioned are the works related to control of HF cavities and the associated amplifiers, electronics, the system of cavity synchronization, power supply, RMN, system commutation grid, pumping equipment, etc. Also, improvements concerning the machine data acquisition and online processing are referred to as well as program cost estimations

  5. Status of the LMFBR development

    Energy Technology Data Exchange (ETDEWEB)

    Taylor, J J

    1975-01-01

    The development of any new power generation system which can make a major contribution to our energy needs is a multi-faceted task involving the utilization of major human and material resources. The LMFBR development, which has the potential for supplying abundant energy for generations, is therefore a large, multi-faceted program. This summary will cover (1) the need for the liquid metal fast breeder reactor, (2) an overall perspective of its development throughout the world, (3) a brief look at the in-depth technological development program in the United States, (4) a description and status of the two major projects now under way in the program, the Fast Flux Test Facility and the Clinch River Breeder Reactor Plant, and (5) a review of the plans for continued development to achieve a reliable, safe and economic power generation system for practical commercial use on the utility networks of the country.

  6. Hyper-X Program Status

    Science.gov (United States)

    McClinton, Charles R.; Reubush, David E.; Sitz, Joel; Reukauf, Paul

    2001-01-01

    This paper provides an overview of the objectives and status of the Hyper-X program, which is tailored to move hypersonic, airbreathing vehicle technology from the laboratory environment to the flight environment. The first Hyper-X research vehicle (HXRV), designated X-43, is being prepared at the Dryden Flight Research Center for flight at Mach 7. Extensive risk reduction activities for the first flight are completed, and non-recurring design activities for the Mach 10 X-43 (third flight) are nearing completion. The Mach 7 flight of the X-43, in the spring of 2001, will be the first flight of an airframe-integrated scramjet-powered vehicle. The Hyper-X program is continuing to plan follow-on activities to focus an orderly continuation of hypersonic technology development through flight research.

  7. PISC: Introduction and status overview

    International Nuclear Information System (INIS)

    Crutzen, S.; Nichols, R.W.

    1994-01-01

    Inspection will be able to play its role in the Structural Integrity assessment scheme and therefore in Pressure Components Safety Assessment. Inspection techniques are or will soon be able to furnish in a reliable way the information needed on the 'Status of the structure' for what concerns the presence, location, size and characteristics of defects. The effectiveness and reliability of these inspections will depend very much on the way in which they will be qualified and PISC III contributes much to the development of qualification schemes and in particular to performance demonstration of inspection procedures. The experimental work of PISC III is now ended and with it the funding of the PISC programme. However, the evaluation and use of PISC data generated by the different Round Robin Tests will certainly continue for several years as well as the cooperation spirit which characterized these 20 years of NDE effectiveness evaluation. (orig.)

  8. Molecular magnetism, status and perspectives

    Science.gov (United States)

    Gatteschi, Dante; Bogani, Lapo; Cornia, Andrea; Mannini, Matteo; Sorace, Lorenzo; Sessoli, Roberta

    2008-12-01

    A short review is made of molecular magnetism, trying to discuss what is alive and well, with perspectives for the future. All the main fields of activity are mentioned, ranging from the so-called spin cross-over systems to the quest for organic (molecular) ferromagnets. Particular attention is devoted to some of the recent advances in these fields, highlighting also the opportunities for the development of applications. Low dimensional magnets are perhaps the best opportunity to use molecules, and the status of single-molecule and single chain magnets is discussed. The last part is devoted to the organization of magnetic molecules and to the development of techniques which allow to measure the magnetic properties of thin layers and, in perspective, of single molecules.

  9. Energy status 2010; Energistatus 2010

    Energy Technology Data Exchange (ETDEWEB)

    Skaansar, Ellen

    2011-07-01

    In the new report, Energy Status NVE provides a unified presentation of statistics and facts about the Norwegian energy system. It gives an overview of the production, transmission and consumption of electricity in the Norwegian society, and shows energy use for various purposes and the relationship between energy and the environment. Norway is the sixth largest hydropower producer in the world and, together with Iceland the highest portion of renewable electricity production of all countries in Europe. In comparison, is about 17 percent of all electricity in the EU based on renewable resources. In Sweden, renewable energy resources account for about half of all electricity production, while the corresponding share in Denmark is about 29 percent. The good supply of water power has contributed to the fact that Norway has a consumption pattern that differs from the countries around us. (AG)

  10. Experimental status of quantum electrodynamics

    International Nuclear Information System (INIS)

    Drell, S.D.

    1980-01-01

    The speech of Drell S. on the symposium dedicated to 60th anniversary of Schwinger J. is presented. The fundamental status of the hero of the day in quantum field theory, which turned into quantum electrodynamics, are stated. The theory has been perfectly experimentally confirmed and now is the main model permitting to explain weak and strong interactions. The attention is paid on the difference between theoretical and experimental values of the electron anomalous magnetic moment (asub(e)) obtained in the sixth order of perturbation theory. It is necessary to carry out calculations in the octic order of the perturbation theory in order to obtain more precise value of asub(e). The theory and the experimental difference is demonstrated on the example of estimation of fine and hyperfine structure of hydrogen, muonium, and positronium

  11. RTNS-II: present status

    International Nuclear Information System (INIS)

    Heikkinen, D.W.; Logan, C.M.

    1980-10-01

    The present status of the RTNS-II facility is described and typical operating parameters are given. A brief discussion is given of the methods used in production of the TiT 2 targets as well as their performance and tritium handling at RTNS-II. The various types of non-interactive beam diagnostics presently in use at the neutron sources are outlined. The on-line computer system which provides a time history of an irradiation and records target performance is described. Examples are listed of several representative experimental programs which have been carried out thus far at RTNS-II. These include both active and passive experiments. Finally, several of the major improvements to the facility made since the beginning of the experimental program are given

  12. Nuclear energy - status and outlook

    Energy Technology Data Exchange (ETDEWEB)

    Rogner, Hans-Holger; MacDonald, Alan

    2007-07-01

    Rising expectations best characterize the current prospects of nuclear power in a world that is confronted with a burgeoning demand for energy, higher energy prices, energy supply security concerns and growing environmental pressures. It appears that the inherent economic and environmental benefits of the technology and its excellent performance record over the last twenty years are beginning to tilt the balance of political opinion and public acceptance in favour of nuclear power. Nuclear power is a cost-effective supply-side technology for mitigating climate change and can make a substantial contribution to climate protection. This paper reviews the current status of nuclear power and its fuel cycle and provides an outlook on where nuclear power may be headed in the short-to-medium run (20 to 40 years from now). (auth)

  13. Status of fission yield data

    International Nuclear Information System (INIS)

    England, T.R.; Blachot, J.

    1988-01-01

    In this paper we summarize the current status of the recent US evaluation for 34 fissioning nuclides at one or more neutron incident energies and for spontaneous fission. Currently there are 50 yields sets, and for each we have independent and cumulative yields and uncertainties for approximately 1100 fission products. When finalized the recommended data will become part of Version VI of the US ENDF/B. Other major evaluations in progress that are included in a recently formed IAEA Coordinated Research Program are also summarized. In a second part we review two empirical models in use to estimate independent yields. Comparison of model estimates with measured data is presented, including a comparison with some recent data obtained from Lohengrin (Cf-249 T). 18 refs., 13 figs., 3 tabs

  14. NA64 Status Report 2018

    CERN Document Server

    Gninenko, Sergei

    2018-01-01

    The experiment NA64 is aimed at a search for a sub-GeV vector mediator (called dark photon A′) of Dark Matter production at the CERN SPS. . The main goal in 2017 was to probe a region of the A′ parameter space of the thermal dark matter model. Ongoing activities on the detector and data analysis are reviewed. The status and results from the NA64 runs in 2016 and 2017 are reported. First results on the search for the X->e+e− decay of a 17 MeV X boson, which could explain the recently observed excess of e+e-pairs from the excited 8Be nucleus transitions, and A'-> e+e- decays are also presented. Ongoing analysis on the decays of axion-like particles and plans for further searches beyond LS2 are also discussed.

  15. Reactor pressure vessel status report

    International Nuclear Information System (INIS)

    Strosnider, J.; Wichman, K.; Elliot, B.

    1994-12-01

    This report gives a brief description of the reactor pressure vessel (RPV), followed by a discussion of the radiation embrittlement of RPV beltline materials and the two indicators for measuring embrittlement, the end-of-license (EOL) reference temperature and the EOL upper-shelf energy. It also summarizes the GL 92-01 effort and presents, for all 37 boiling water reactor plants and 74 pressurized water reactor plants in the United States, the current status of compliance with regulatory requirements related to ensuring RPV integrity. The staff has evaluated the material data needed to predict neutron embrittlement of the reactor vessel beltline materials. These data will be stored in a computer database entitled the reactor vessel integrity database (RVID). This database will be updated annually to reflect the changes made by the licensees in future submittals and will be used by the NRC staff to assess the issues related to vessel structural integrity

  16. ATLAS construction: A status report

    CERN Document Server

    Sfyrla, Anna

    2006-01-01

    ATLAS is a general purpose p-p collider detector being constructed for the CERN Large Hadron Collider (LHC). It is located in one of the two high luminosity bunch crossing points (peak luminosity of 1 0 3 4 c m - 2 s _ 1 ) of the LHC. It consists of 3 main sections. Located close to the beam axis, the tracking system employs pixel detectors, silicon microstrip modules and transition radiation straws, all within a 2 Tesla superconducting solenoid. The tracker is surrounded by the electromagnetic and hadronic calorimeters. In the outer part of the detector, 8 superconducting coils define an open toroidal magnetic field for muon detection. The construction status of the ATLAS detector towards being ready for the first collisions in 2007 will be presented, with particular emphasis on the construction and projected performance of the tracking system.

  17. Plant status monitor system description

    International Nuclear Information System (INIS)

    Prather, W.A.; Sly, G.A.

    1987-01-01

    In today's regulatory and financial environment, improving plant efficiency and safety are necessary elements of plant operations. Public utility commissions are making rate rulings based, in part, on plant availability performance; and the NRC is putting more emphasis on plant operational aspects. This comes at a time when operating, maintaining, and managing a plant are becoming increasingly complex; moreover, the desired number of experienced plant personnel are becoming more difficult to find. This situation can be partially resolved by using computer software tools to assist operations, maintenance, engineering, and management personnel. These software tools provide information and interpretations based on plant and equipment status. They support improved plant availability, technical specification compliance, and administrative functions. A key element or computerization is the ability to operate on integrated information

  18. Status of the DIRAC Project

    International Nuclear Information System (INIS)

    Casajus, A; Ciba, K; Fernandez, V; Graciani, R; Hamar, V; Mendez, V; Poss, S; Sapunov, M; Stagni, F; Tsaregorodtsev, A; Ubeda, M

    2012-01-01

    The DIRAC Project was initiated to provide a data processing system for the LHCb Experiment at CERN. It provides all the necessary functionality and performance to satisfy the current and projected future requirements of the LHCb Computing Model. A considerable restructuring of the DIRAC software was undertaken in order to turn it into a general purpose framework for building distributed computing systems that can be used by various user communities in High Energy Physics and other scientific application domains. The CLIC and ILC-SID detector projects started to use DIRAC for their data production system. The Belle Collaboration at KEK, Japan, has adopted the Computing Model based on the DIRAC system for its second phase starting in 2015. The CTA Collaboration uses DIRAC for the data analysis tasks. A large number of other experiments are starting to use DIRAC or are evaluating this solution for their data processing tasks. DIRAC services are included as part of the production infrastructure of the GISELA Latin America grid. Similar services are provided for the users of the France-Grilles and IBERGrid National Grid Initiatives in France and Spain respectively. The new communities using DIRAC started to provide important contributions to its functionality. Among recent additions can be mentioned the support of the Amazon EC2 computing resources as well as other Cloud management systems; a versatile File Replica Catalog with File Metadata capabilities; support for running MPI jobs in the pilot based Workload Management System. Integration with existing application Web Portals, like WS-PGRADE, is demonstrated. In this paper we will describe the current status of the DIRAC Project, recent developments of its framework and functionality as well as the status of the rapidly evolving community of the DIRAC users.

  19. Status report on radionuclide transfer

    International Nuclear Information System (INIS)

    1980-01-01

    At the suggestion of the Federal Minstry of the Interior, in June 1978, a group of scientists from several institutions who are active in the field of radionuclide transfer or are interested in these problems got together. During the discussions of the work team, especially the transfer soil/plants was emphasized. Then the work team set up a status report on the transfer of the radionuclides relevant in the sense of the radiation protection act. The nuclides H 3 and C14, the isotopes of the Sr, J, and Cs, Tc99, the so-called corrosion nuclides Mn54, Fe59, co-isotopes and Zn65, and isotopes of Pu, Am, and Cm were regarded as important for a possible radiation exposition. Recent investigations revealed that also the natural radionuclides Ra226, Po210, and Pb210 should be covered by the investigations. The goal of this status report is to present the level of knowledge on the transfer of these radionuclides to man in a brief form, giving hints at the most important literature. It was requested by the Federal Ministry of the Interior, as fas as possible, to indicate transfer factors which are necessary for the radio-occology act to be decreed according to Para. 45 of the radiation protection act. Another goal of the report was to show the gap in the knowledge on the radio nuclide transfer. This was thought to help to create a basis for the decisions of the Federal Ministry concerning the support of other investigation projects in the field of transfer of radionuclides. (orig./MG) [de

  20. LSST telescope and site status

    Science.gov (United States)

    Gressler, William J.

    2016-07-01

    The Large Synoptic Survey Telescope (LSST) Project1 received its construction authorization from the National Science Foundation in August 2014. The Telescope and Site (T and S) group has made considerable progress towards completion in subsystems required to support the scope of the LSST science mission. The LSST goal is to conduct a wide, fast, deep survey via a 3-mirror wide field of view optical design, a 3.2-Gpixel camera, and an automated data processing system. The summit facility is currently under construction on Cerro Pachón in Chile, with major vendor subsystem deliveries and integration planned over the next several years. This paper summarizes the status of the activities of the T and S group, tasked with design, analysis, and construction of the summit and base facilities and infrastructure necessary to control the survey, capture the light, and calibrate the data. All major telescope work package procurements have been awarded to vendors and are in varying stages of design and fabrication maturity and completion. The unique M1M3 primary/tertiary mirror polishing effort is completed and the mirror now resides in storage waiting future testing. Significant progress has been achieved on all the major telescope subsystems including the summit facility, telescope mount assembly, dome, hexapod and rotator systems, coating plant, base facility, and the calibration telescope. In parallel, in-house efforts including the software needed to control the observatory such as the scheduler and the active optics control, have also seen substantial advancement. The progress and status of these subsystems and future LSST plans during this construction phase are presented.

  1. Status Epilepticus in the Emergency Department

    Directory of Open Access Journals (Sweden)

    Jonathan Lee

    2017-04-01

    Full Text Available Audience: This simulation can be used for EM learners of any level including medical students, junior residents and senior residents. Introduction: Seizures are the result of abnormal or disorganized cortical electrical activity in the brain. Status epilepticus is a dangerous complication of seizures. In adults and children older than five years old, generalized, convulsive status epilepticus refers to greater than 5 minutes of a continuous seizure OR two or more discrete seizures between which there is incomplete recovery of consciousness As with all emergency situations treatment must occur simultaneously while the physician manages primary assessment and resuscitation and determines the underlying cause. Objectives: At the end of this simulation session, the learner will: 1 Demonstrate the management of status epilepticus 2 Justify when airway intervention is needed for status epilepticus 3 Describe risk factors for status epilepticus 4 Prepare a differential diagnosis for the causes in status epilepticus. Method: This educational session is a high-fidelity simulation.

  2. Renewables 2014. Global status report 2014

    International Nuclear Information System (INIS)

    Sawin, Janet L.; Sverrisson, Freyr; Chawla, Kanika; Lins, Christine; Adib, Rana; Hullin, Martin; Leitner, Sarah; Mazzaccaro, Stefano; Murdock, Hannah; Williamson, Laura E.; Wright, Glen; McCrone, Angus; Musolino, Evan; Mastny, Lisa; Lily Riahi; Sims, Ralph; Jonathan Skeen; Sverrisson, Freyr; Martinot, Eric

    2014-01-01

    The Renewables Global Status Report provides a comprehensive and timely overview of renewable energy market, industry, investment, and policy developments worldwide. It enables policy-makers, industry, investors, and civil society to make informed decisions. The report covers recent developments, current status, and key trends; by design, it does not provide analysis or forecast. The Renewables Global Status Report relies on up-to-date renewable energy data, provided by an international network of more than 500 contributors, researchers, and authors

  3. Emergency Surgery for Refractory Status Epilepticus.

    Science.gov (United States)

    Botre, Abhijeet; Udani, Vrajesh; Desai, Neelu; Jagadish, Spoorthy; Sankhe, Milind

    2017-08-15

    Management of refractory status epilepticus in children is extremely challenging. Two children with medically refractory status epilepticus, both of whom had lesional pathology on MRI and concordant data on EEG and PET scan. Emergency hemispherotomy performed in both patients. A complete, sustained seizure freedom obtained postoperatively. Emergency surgery is a treatment option in selected cases of drug refractory status epilepticus with lesional pathology and concordant data.

  4. Less Common Etiologies of Status Epilepticus

    Science.gov (United States)

    Bleck, Thomas P

    2010-01-01

    Status epilepticus is treated as a neurologic emergency and only later are the potential etiologies assessed. While sometimes the cause for status epilepticus is apparent (e.g., antiepileptic drug withdrawal), all too often it is not identified, even after extensive diagnostic testing has been performed. With emphasis on the less-common etiologies, this review will cover various probable and known causes of status epilepticus among adults, children, and those patients with refractory epilepsy. PMID:20231917

  5. Nuclear status report for western Europe 1984

    International Nuclear Information System (INIS)

    Krejsa, P.; Laurent, L.; Lauridsen, K.

    1985-01-01

    The status report embraces the following countries: Austria, Belgium, Denmark, Finland, France, Federal Republic of Germany, Greece, Italy, The Netherlands, Spain, Sweden, Switzerland, United Kingdom, Yugoslavia

  6. Anxiety, Depression, and Functional Status Are the Best Predictors of Health Status Patients With Heart Failure

    National Research Council Canada - National Science Library

    DeJong, Marla

    2004-01-01

    .... Therefore, health status is an increasingly important concept in the management of HF. In fact, most symptomatic patients are more concerned about their everyday health status than the length of their life...

  7. When status is grabbed and when status is granted: Getting ahead in dominance and prestige hierarchies.

    Science.gov (United States)

    de Waal-Andrews, Wendy; Gregg, Aiden P; Lammers, Joris

    2015-09-01

    What type of behaviour affords status, agentic, or communal? Research to date has yielded inconsistent answers. In particular, the conflict view holds that agentic behaviour permits the imperious to grab status through overt force, whereas the functional view holds that communal behaviour permits the talented to earn status through popular appeal. Here, we synthesize both views by taking into account the moderating role played by group hierarchy. Group hierarchy can range from being dominance based (where status is grabbed) to prestige based (where status is granted). In a field study (Study 1), and a laboratory experiment (Study 2), we demonstrate that in different groups, status can be achieved in different ways. Specifically, agentic behaviour promotes status regardless of hierarchy type, whereas the effect of communal behaviour on status is moderated by hierarchy type: it augments it in more prestige-based hierarchies but diminishes it in more dominance-based hierarchies. © 2014 The British Psychological Society.

  8. MARS Validation Plan and Status

    International Nuclear Information System (INIS)

    Ahn, Seung-hoon; Cho, Yong-jin

    2008-01-01

    The KINS Reactor Thermal-hydraulic Analysis System (KINS-RETAS) under development is directed toward a realistic analysis approach of best-estimate (BE) codes and realistic assumptions. In this system, MARS is pivoted to provide the BE Thermal-Hydraulic (T-H) response in core and reactor coolant system to various operational transients and accidental conditions. As required for other BE codes, the qualification is essential to ensure reliable and reasonable accuracy for a targeted MARS application. Validation is a key element of the code qualification, and determines the capability of a computer code in predicting the major phenomena expected to occur. The MARS validation was made by its developer KAERI, on basic premise that its backbone code RELAP5/MOD3.2 is well qualified against analytical solutions, test or operational data. A screening was made to select the test data for MARS validation; some models transplanted from RELAP5, if already validated and found to be acceptable, were screened out from assessment. It seems to be reasonable, but does not demonstrate whether code adequacy complies with the software QA guidelines. Especially there may be much difficulty in validating the life-cycle products such as code updates or modifications. This paper presents the plan for MARS validation, and the current implementation status

  9. Status epilepticus in scrub typhus.

    Science.gov (United States)

    Kalita, Jayantee; Mani, Vinita E; Bhoi, Sanjeev K; Misra, Usha K

    2016-07-01

    Scrub typhus is an emerging infection, and there is little information about status epilepticus (SE) in scrub typhus. We report the clinical spectrum and outcome of SE in scrub typhus. In a 3-year prospective hospital-based observational study, all scrub typhus patients with SE were included. Scrub typhus was diagnosed by immunochromatography assay. SE was defined if convulsions lasted longer than 5 min. The patients' demographic, clinical, computed tomography (CT), magnetic resonance imaging (MRI), and electroencephalography (EEG) findings were noted. Response to antiepileptic drugs (AEDs) and outcome at 1 month and 1 year were recorded. Between 2012 and 2014, there were 66 patients with scrub typhus admitted with central nervous system (CNS) involvement, 10 (15.2%) of whom had SE (generalized convulsions in 5, secondary generalized in one). The median age of the patients was 34 (range 18-71) years and seven were female. The duration of SE ranged between 10 min and 48 h. SE responded to one AED in five patients, two AEDs in three patients, and more than two AEDs in two patients. Cranial MRI findings were normal. All patients recovered completely with doxycycline by 1 month and AED was withdrawn by 8 months in all. Although 15% patients with scrub typhus may have SE, they have good outcome. Wiley Periodicals, Inc. © 2016 International League Against Epilepsy.

  10. Status report on geochemical modelling

    International Nuclear Information System (INIS)

    Read, D.

    1991-12-01

    This report describes the findings of a review undertaken on behalf of the project management group of the programme 'Endlagersicherheit in der Nachbetriebsphase' based at GSF-IfT (Forschungszentrum fuer Umwelt und Gesundheit - Institut fuer Tieflagerung) to establish the current status of research into the simulation of geochemical processes relevant to radiological assessment. The review is intended to contribute to Stage 1 of a strategy formulated to enhance the use of geochemical models in Germany. Emphasis has been placed on processes deemed to be of greatest relevance to performance assessment for a HLW-repository in a salt dome principally, speciation-solubility in high salinity solutions, complexation by natural organics and generation-transport of colloids. For each of these and other topics covered, a summary is given of fundamental concepts, theoretical representations and their limitations, highlighting, where appropriate, the advantages and disadvantages of alternative approaches. The availability of data to quantify any given representation is addressed, taking into account the need for information at elevated temperatures and pressures. Mass transfer is considered in terms of aqueous, particulate and gas-mediated transport, respectively. (orig.) [de

  11. Status of the GERDA experiment

    International Nuclear Information System (INIS)

    Medinaceli, E.

    2016-01-01

    The GERDA experiment is designed to search for neutrinoless double beta decay (0νββ) using "7"6Ge, therefore asses the nature of neutrinos (Dirac or Majorana). In the so-called Phase I, with an exposure of 21.6 kr yr, GERDA reached a background index (BI) of 10"−"2 cts/(keV kg yr) at 90% CL No signal was found during this phase and a lower limit on the process half-life of 2.1 × 10"2"5 yr was derived (90% CL). GERDA is currently being upgraded to its Phase II, where the "7"6Ge mass will be double, and it is expected to reduce by an order of magnitude the BI. For 0νββ half-lives at the order of 10"2"6 yr will be derived in the absence of signal. The experimental techniques used by GERDA will be depicted and the most relevant results from Phase I will be shown; as well as details on the upgrades of Phase II, including the status of the additional detectors deployed recently, and the new background reduction techniques using the active liquid Argon veto.

  12. Status of Gerda Phase II

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, Victoria [Max-Planck-Institut fuer Kernphysik, Heidelberg (Germany); Collaboration: GERDA-Collaboration

    2016-07-01

    The GERDA experiment is designed to search for neutrinoless double beta (0νββ) decay of {sup 76}Ge. In Phase I of the experiment a background index (BI) of 10{sup -2} cts/(keV.kg.yr) was reached. No signal has been found and a lower limit on the half-life of 2.1.10{sup 25} yr (at 90% C.L.) is extracted. The aim of Phase II is to double the Ge mass and further reduce the BI by an order of magnitude to explore half-lives of about 10{sup 26} yr. Thirty new Broad Energy Germanium (BEGe) detectors have been produced. These detectors are distinct for their improved energy resolution and enhanced pulse shape discrimination of signal from background events. Further background reduction will be reached by an active veto to read out argon scintillation light. The Phase II commissioning showed that two of the major background components, external γ-rays from {sup 214}Bi and {sup 208}Tl decays, can be suppressed up to two orders of magnitude. This talk presents the current status of the GERDA Phase II upgrade.

  13. Status of the GERDA experiment

    Science.gov (United States)

    Medinaceli, E.; Gerda Collaboration

    2017-07-01

    The GERDA experiment is designed to search for neutrinoless double beta decay (0νββ) using ^{76} Ge, therefore asses the nature of neutrinos (Dirac or Majorana). In the so-called Phase I, with an exposure of 21.6kr yr, GERDA reached a background index (BI) of 10^{-2}{ cts/(keV kg yr)} at 90% CL No signal was found during this phase and a lower limit on the process half-life of 2.1×10^{25}{ yr} was derived (90% CL). GERDA is currently being upgraded to its Phase II, where the ^{76} Ge mass will be double, and it is expected to reduce by an order of magnitude the BI. For 0νββ half-lives at the order of 10^{26}{ yr} will be derived in the absence of signal. The experimental techniques used by GERDA will be depicted and the most relevant results from Phase I will be shown; as well as details on the upgrades of Phase II, including the status of the additional detectors deployed recently, and the new background reduction techniques using the active liquid Argon veto.

  14. WFIRST: Project Overview and Status

    Science.gov (United States)

    Kruk, Jeffrey; WFIRST Formulation Science Working Group, WFIRST Project Team

    2018-01-01

    The Wide-Field InfraRed Survey Telescope (WFIRST) will be the next Astrophysics flagship mission to follow JWST. The observatory payload consists of a Hubble-size telescope aperture with a wide-field NIR instrument and a coronagraph operating at visible wavelengths and employing state-of-the-art wavefront sensing and control. The Wide-field instrument is optimized for large area NIR imaging and spectroscopic surveys, with performance requirements driven by programs to study cosmology and exoplanet detection via gravitational microlensing. All data will be public immediately, and a substantial guest observer program will be supported.The WFIRST Project is presently in Phase A, with a transition to Phase B expected in early to mid 2018. Candidate observing programs are under detailed study in order to inform the mission design, but the actual science investigations will not be selected until much closer to launch. We will present an overview of the present mission design and expected performance, a summary of Project status, and plans for selecting the observing programs.

  15. Industry outreach a status report

    Energy Technology Data Exchange (ETDEWEB)

    Surek, D.; Sen, R. [R.K. Sen & Associates, Inc., Bethesda, MD (United States)

    1995-09-01

    The Outreach Project was initiated in October 1994 with the objective of developing a multi-year plan for the U.S. Department of Energy (DOE) for targeted outreach activities for stakeholders in industry and the general public. This status report summarizes the work on industry outreach that has been completed since the inception of the project in October 1994. A three-pronged approach was taken to ascertain issues related to industry outreach. First, there was a review of on-going and past industry outreach activities at DOE and NHA. Next, a series of meetings with industry decision makers was arranged to get a better understanding of industry interests and concerns, and to discuss how DOE and industry could work collaboratively to develop hydrogen energy systems. Third, a workshop is scheduled where representatives from industry, DOE and other federal agencies can identify issues that would enhance partnering between the federal government and industry in the development of hydrogen energy systems. At this tiny, the review of on-going and past activities has been completed. Industry interviews are in progress and a majority of meetings have been held. Analysis of the information gained is in progress. The preliminary analysis of this information indicates that for appropriate near-term demonstration-type projects, the level of interest for collaboration between DOE and industry is high. The data also identifies issues industry is concerned with which impact the commercialization of hydrogen energy systems.

  16. Renewables 2012 - Global status report

    International Nuclear Information System (INIS)

    Sawin, Janet L.; Bhattacharya, Sribas Chandra; Galan, Ernesto Macias; McCrone, Angus; Moomaw, William R.; Sims, Ralph; Sonntag-O'Brien, Virginia; Sverrisson, Freyr; Chawla, Kanika; Adib, Rana; Musolino, Evan; Mastny, Lisa; Skeen, Jonathan; Martinot, Eric; Hinrichs-Rahlwes, Rainer

    2012-01-01

    Renewable energy markets and policy frameworks have evolved rapidly in recent years. This report provides a comprehensive and timely overview of renewable energy market, industry, investment, and policy developments worldwide. It relies on the most recent data available, provided by a network of more than 400 contributors and researchers from around the world, all of which is brought together by a multi-disciplinary authoring team. The report covers recent developments, current status, and key trends; by design, it does not provide analysis or forecast the future. As such, this report and subsequent editions will serve as a benchmark for measuring global progress in the deployment of renewable energy, which is of particular interest in this International Year of Sustainable Energy for All. UN Secretary-General Ban Ki-moon has marked the occasion with a new global initiative, Sustainable Energy for All, which seeks to mobilise global action on three inter-linked objectives to be achieved by 2030: universal access to modern energy services, improved rates of energy efficiency, and expanded use of renewable energy sources

  17. Vitamin D Status in Korea

    Directory of Open Access Journals (Sweden)

    Han Seok Choi

    2013-03-01

    Full Text Available The majority of the vitamin D in our body is produced by cutaneous synthesis in response to sunlight. As more and more people live in cities and spend the bulk of their time indoors, it can be difficult to get sufficient sun exposure for adequate cutaneous production of vitamin D. Therefore, vitamin D insufficiency has become a very common health problem worldwide. The Korea National Health and Nutrition Examination Survey IV 2008 showed that the prevalence of vitamin D insufficiency, defined as a serum 25-hydroxyvitamin D [25(OHD] level below 50 nmol/L, was 47.3% in males and 64.5% in females. Only 13.2% of males and 6.7% of females had a serum 25(OHD level of greater than 75 nmol/L. In Korea, vitamin D insufficiency was more prevalent in young adults than in elderly people, likely due to the indoor lifestyle of younger people. Compared with the United States and Canada, Korea has a lower mean 25(OHD level and a higher prevalence of vitamin D insufficiency. To improve the vitamin D status of the Korean population, more aggressive policies on food fortification and vitamin D supplementation are needed.

  18. Current Status of RENO Experiment

    International Nuclear Information System (INIS)

    Kim, Soo-Bong

    2010-01-01

    The RENO (Reactor Experiment for Neutrino Oscillation) is under construction to measure the value of the smallest and unknown neutrino mixing angle θ 13 . The experiment will compare the measured fluxes of electron antineutrinos at two detectors located at 290 m and 1.4 km distances from the center of the Yonggwang nuclear reactors in Korea, with world-second largest thermal power output of 16.4 GW. Construction of experimental halls and access tunnels for both near and far detector sites was completed in early 2009. The detectors are near completion, and data-taking is planned to start in mid 2010. An expected number of observed antineutrino is roughly 510 and 80 per day in the near detector and far detector, respectively. An estimated systematic uncertainty associated with the measurement is less than 0.6%, and an expected statistical error is about 0.3%. With three years of data, the experiment will search for the mixing angle values of sin 2 (2θ 13 ) down to 0.02 in 90% C.L. limit. In this talk, the construction status will be presented. (author)

  19. Status of uranium in Brazil

    International Nuclear Information System (INIS)

    Majdalani, S.A.; Tavares, A.M.

    2001-01-01

    Uranium exploration in Brazil was started in 1952 by the Brazilian National Research Council. This led to the discovery of the first uranium deposits in Pocos de Caldas and Jacobina. These activities was later continued by the National Energy Commission/Comissao Nacional de Energia Nuclear (CNEN), formed in 1962. The founding of NUCLEBRAS at the end of 1974 marked the increasing effort of the country's uranium exploration programme. At this time only the Pocos de Caldas deposit was known with measurable resources. Due to the reorganization of the Brazilian nuclear programme in 1988, all uranium exploration in the country was stopped. By then, eight areas with uranium reserves has been identified. Brazil uranium resources in the RAR category at ≤ $80/kg U cost range are estimated to be 162,000 tonnes U, out of which 56,100 tonnes are in the ≤ $40/kg U cost range. Additional resources in the EAR-I category and the cost range ≤ 80/kg U are in the order of 100,200 tonnes U. The first production of uranium in Brazil, at the Osamu Utsumi mine (Pocos de Caldas deposit), started in 1982. Because of escalated costs and reduced demand, this activity was put on stand-by status between 1990 and 1992. The mine was restarted in 1993, but was stopped again in October 1995. The cumulative production of the mine to 1996 was 1241 tonnes U. The Lagoa Real deposit is currently being prepared as a new producing mine. (author)

  20. Status of rod consolidation, 1988

    International Nuclear Information System (INIS)

    Bailey, W.J.

    1989-01-01

    It is estimated that the spent fuel storage pools at some domestic light-water reactors will run out of space before 2003, the year that the US Department of Energy currently predicts it will have a repository available. Of the methods being studied to alleviate the problem, rod consolidation is one of the leading candidates for achieving more efficient use of existing space in spent fuel storage pools. Rod consolidation involves mechanically removing all the fuel rods from the fuel assembly hardware (i.e., the structural components) and placing the fuel rods in a close-packed array in a canister without space grids. A typical goal of rod consolidation systems is to insert the fuel rods from two fuel assemblies into a canister that has the same exterior dimensions as one standard fuel assembly (i.e., to achieve a consolidation or compaction ratio of 2:1) and to compact the nonfuel-bearing structural components from those two fuel assemblies by a factor of 10 to 20. This report provides an overview of the current status of rod consolidation in the United States and a small amount of information on related activities in other countries. 85 refs., 36 figs., 5 tabs

  1. [Management of pediatric status epilepticus].

    Science.gov (United States)

    Vargas L, Carmen Paz; Varela E, Ximena; Kleinsteuber S, Karin; Cortés Z, Rocío; Avaria B, María de Los Ángeles

    2016-01-01

    Pediatric Status Epilepticus (SE) is an emergency situation with high morbidity and mortality that requires early and aggressive management. The minimum time criterion to define SE was reduced from 30 to 5 minutes, defined as continuous seizure activity or rapidly recurrent seizures without resumption of consciousness for more than 5 minutes. This definition considers that seizures that persist for > 5 minutes are likely to do so for more than 30 min. Those that persist for more than 30 minutes are more difficult to treat. Refractory SE is the condition that extends beyond 60-120 minutes and requires anesthetic management. Super-refractory SE is the state of no response to anesthetic management or relapse during withdrawal of these drugs. The aim of this review is to provide and update on convulsive SE concepts, pathophysiology, etiology, available antiepileptic treatment and propose a rational management scheme. A literature search of articles published between January 1993 and January 2013, focused on pediatric population was performed. The evidence about management in children is limited, mostly corresponds to case series of patients grouped by diagnosis, mainly adults. These publications show treatment alternatives such as immunotherapy, ketogenic diet, surgery and hypothermia. A 35% mortality, 26% of neurological sequelae and 35% of recovery to baseline condition is described on patient’s evolution.

  2. Current status of nuclear power

    International Nuclear Information System (INIS)

    Behnke, W.B.

    1984-01-01

    The decision to devote the 1984 conference to nuclear power is timely and appropriate. Illinois has a long, and distinguished history in the development of civilian nuclear power. The concept was born at the University of Chicago, developed at Argonne National Laboratory and demonstrated on the Commonwealth Edison system at our pioneer Dresden Nuclear Station. Today, Illinois ranks number one in the nation in nuclear generation. With over a quarter century of commercial operating experience, nuclear power has proven its worth and become a significant and growing component of electric power supply domestically and throughout the world. Despite its initial acceptance, however, the nuclear power industry in the U.S. is now in the midst of a difficult period of readjustment stemming largely from the economic and regulatory problems of the past decade. As a result, the costs of plants under construction have increased dramatically, causing serious financial difficulties for several projects and their owners. At the same time, the U.S. is facing hard choices concerning its future energy supplies. Conferences such as this have an important role in clarifying the issues and helping to find solutions to today's pressing energy problems. This paper summarizes the status of nuclear power both here and abroad, discussing the implications of current events in the context of national energy policy and economic development here in Illinois

  3. Status and prospects for CUORE

    Science.gov (United States)

    Canonica, L.; Alduino, C.; Alfonso, K.; Artusa, D. R.; Avignone, F. T., III.; Azzolini, O.; Banks, T. I.; Bari, G.; Beeman, J. W.; Bellini, F.; Bersani, A.; Biassoni, M.; Branca, A.; Brofferio, C.; Bucci, C.; Camacho, A.; Caminata, A.; Cao, X. G.; Capelli, S.; Cappelli, L.; Carbone, L.; Cardani, L.; Carniti, P.; Casali, N.; Cassina, L.; Chiesa, D.; Chott, N.; Clemenza, M.; Copello, S.; Cosmelli, C.; Cremonesi, O.; Creswick, R. J.; Cushman, J. S.; D'Addabbo, A.; Dafinei, I.; Davis, C. J.; Dell'Oro, S.; Deninno, M. M.; Di Domizio, S.; Di Vacri, M. L.; Drobizhev, A.; Fang, D. Q.; Faverzani, M.; Fernandes, G.; Ferri, E.; Ferroni, F.; Fiorini, E.; Franceschi, M. A.; Freedman, S. J.; Fujikawa, B. K.; Giachero, A.; Gironi, L.; Giuliani, A.; Gladstone, L.; Gorla, P.; Gotti, C.; Gutierrez, T. D.; Haller, E. E.; Han, K.; Hansen, E.; Heeger, K. M.; Hennings-Yeomans, R.; Hickerson, K. P.; Huang, H. Z.; Kadel, R.; Keppel, G.; Kolomensky, Yu G.; Leder, A.; Ligi, C.; Lim, K. E.; Liu, X.; Ma, Y. G.; Maino, M.; Marini, L.; Martinez, M.; Maruyama, R. H.; Mei, Y.; Moggi, N.; Morganti, S.; Mosteiro, P. J.; Napolitano, T.; Nones, C.; Norman, E. B.; Novati, V.; Nucciotti, A.; O'Donnell, T.; Orio, F.; Ouellet, J. L.; Pagliarone, C. E.; Pallavicini, M.; Palmieri, V.; Pattavina, L.; Pavan, M.; Pessina, G.; Pettinacci, V.; Piperno, G.; Pirro, S.; Pozzi, S.; Previtali, E.; Rosenfeld, C.; Rusconi, C.; Sangiorgio, S.; Santone, D.; Scielzo, N. D.; Singh, V.; Sisti, M.; Smith, A. R.; Taffarello, L.; Tenconi, M.; Terranova, F.; Tomei, C.; Trentalange, S.; Vignati, M.; Wagaarachchi, S. L.; Wang, B. S.; Wang, H. W.; Wilson, J.; Winslow, L. A.; Wise, T.; Woodcraft, A.; Zanotti, L.; Zhang, G. Q.; Zhu, B. X.; Zimmermann, S.; Zucchelli, S.

    2017-09-01

    CUORE is a cryogenic detector consisting of 988 TeO2 crystals, 750 g each, and will be operated at a temperature of ˜10 mK, to search for neutrinoless double beta decay (0νββ) of 130Te. The detector, in the final stages of construction at the Laboratori Nazionali del Gran Sasso (Italy), will start its operations in 2016. CUORE-0, its pilot experiment, has proven the feasibility of CUORE, demonstrating that the target background of 0.01 counts/keV/kg/y and the energy resolution of 5 keV are within reach. CUORE-0 also made the most precise measurement of the 2νββ decay. The expected sensitivity of CUORE to the 0νββ 130Te half-life is 9 ·1025y, for 5 years of data taking. Here, we report the most recent results of CUORE-0, their implications for CUORE, and the current status of the CUORE experiment.

  4. Pinon Pine IGCC project status

    International Nuclear Information System (INIS)

    Higginbotham, E.B.; Lamarre, L.J.; Glazer, M.

    1993-01-01

    Sierra Pacific Power Company (SPPCo) intends to build the Pinon Pine Power Project, an integrated coal gasification combined cycle (IGCC) plant at its Tracy Power Station near Reno, Nevada. The plant will burn approximately 800 tons of coal per day to generate electricity in a base load application. The Pinon Project was selected by the U.S. Department of Energy (DOE) for funding under Round IV of the Clean Coal Technology Program. The project will demonstrate the use of the KRW agglomerating fluidized bed gasifer operating in the air blown mode. Hot gas cleanup consisting of particulate and sulfur removal will also be demonstrated. The Cooperative Agreement between SPPCo and the DOE was executed in August 1992. Foster Wheeler USA Corporation (FWUSA) will provide engineering and construction management services. The M.W. Kellogg Company (MWK) will provide engineering of the gasifer and hot gas cleanup systems. A discussion of project progress since the 1992 Clean Coal Technology Conference, design and economic considerations, and current project status is presented

  5. Status report of PEP-4

    International Nuclear Information System (INIS)

    Kamae, Tuneyoshi

    1982-01-01

    The present status of PEP-4 is reported. The cosmic ray test of a TPC without magnetic field was done in July, 1981, and tracks were observed on the first day of the test. The entire PEP-4 detector was tested with 3.9 kG magnetic field in November, 1981, and various trigger configurations were tested. The TPC performed well during the test, and a preliminary analysis gave an encouraging position resolution which is expected to be improved with the correction for various non-uniformity and by refining the fitting procedure. Furthermore, the detection efficiency of the muon chamber was about 99 %. In November and December, 1981, the cosmic ray test of the hexagonal calorimeter was carried out. The performance was just as expected. Noise did not pose any problem, and the peak of the Fourier coefficient gave a nice overall calibration of the calorimeter. There are some problems to be solved in future. With the TPC, the impurities in the gas, the electronic noise, the hooks and the magnetic coil should be improved. In addition, there are some problems with the inner drift chamber, the hexagonal calorimeter and the relativistic rise measured by the TPC. The very recent results with the first e + e - beam obtained in February, 1982, are briefly reported, although the events have not been fully analyzed. (Ito, K.)

  6. Status and prospects for reprocessing

    International Nuclear Information System (INIS)

    Rossney, G.K.

    1977-01-01

    Following the formation of United Reprocessors (U.R.G.) in 1976 by British Nuclear Fuels Limited (B.N.F.L.) in the United Kingdom, the Commissariat a l'Energie Atomique (C.E.A.) in France and K.E.W.A. Kernbrennstoff-Wiederaufarbeitungs-Gesellschaft MBH (K.E.W.A.) in Germany, collaboration is now well established for the marketing of their reprocessing services for irradiated oxide fuel from thermal reactors. In addition collaboration in the continued evolution of the technology has progressed and an extensive research and development programme has been established, the results of which are exchanged between the shareholders. During 1976 the U.K. Government has given approval to B.N.F.L. to sign further contracts with foreign customers, subject to certain conditions. In France, the fuel cycle activities of the C.E.A. have been vested in a new company (Compagnie Generale Des Matieres Nucleaires (C.O.G.E.M.A.)) and their La Hague plant has commenced reprocessing operations on irradiated oxide fuel. In Germany, an agreement has been signed between K.E.W.A. and P.W.K. for the pre-project study for the proposed German plant. Against this background this paper reviews the present status of reprocessing by the shareholders of U.R.G. and the prospects for reprocessing

  7. Aging, Nutritional Status and Health

    Directory of Open Access Journals (Sweden)

    Wilma Leslie

    2015-07-01

    Full Text Available The older population is increasing worldwide and in many countries older people will outnumber younger people in the near future. This projected growth in the older population has the potential to place significant burdens on healthcare and support services. Meeting the diet and nutrition needs of older people is therefore crucial for the maintenance of health, functional independence and quality of life. While many older adults remain healthy and eat well those in poorer health may experience difficulties in meeting their nutritional needs. Malnutrition, encompassing both under and over nutrition increases health risks in the older population. More recently the increase in obesity, and in turn the incidence of chronic disease in older adults, now justifies weight management interventions in obese older adults. This growing population group is becoming increasingly diverse in their nutritional requirements. Micro-nutrient status may fluctuate and shortfalls in vitamin D, iron and a number of other nutrients are relatively common and can impact on well-being and quality of life. Aging presents a number of challenges for the maintenance of good nutritional health in older adults.

  8. Status of the SXFEL Facility

    Directory of Open Access Journals (Sweden)

    Zhentang Zhao

    2017-06-01

    Full Text Available The Shanghai soft X-ray Free-Electron Laser facility (SXFEL is being developed in two steps; the SXFEL test facility (SXFEL-TF, and the SXFEL user facility (SXFEL-UF. The SXFEL-TF is a critical development step towards the construction a soft X-ray FEL user facility in China, and is under commissioning at the Shanghai Synchrotron Radiation Facility (SSRF campus. The test facility is going to generate 8.8 nm FEL radiation using an 840 MeV electron linac passing through the two-stage cascaded HGHG-HGHG or EEHG-HGHG (high-gain harmonic generation, echo-enabled harmonic generation scheme. The construction of the SXFEL-TF started at the end of 2014. Its accelerator tunnel and klystron gallery were ready for equipment installation in April 2016, and the installation of the SXFEL-TF linac and radiator undulators were completed by the end of 2016. In the meantime, the SXFEL-UF, with a designated wavelength in the water window region, began construction in November 2016. This was based on upgrading the linac energy to 1.5 GeV, and the building of a second undulator line and five experimental end-stations. Construction status and the future plans of the SXFEL are reported in this paper.

  9. Monitor for status epilepticus seizures

    Science.gov (United States)

    Johnson, Mark; Simkins, Thomas

    1994-01-01

    This paper describes the sensor technology and associated electronics of a monitor designed to detect the onset of a seizure disorder called status epilepticus. It is a condition that affects approximately 3-5 percent of those individuals suffering from epilepsy. This form of epilepsy does not follow the typical cycle of start-peak-end. The convulsions continue until medically interrupted and are life threatening. The mortality rate is high without prompt medical treatment at a suitable facility. The paper describes the details of a monitor design that provides an inexpensive solution to the needs of those responsible for the care of individuals afflicted with this disorder. The monitor has been designed as a cooperative research and development effort involving the United States Army Armament Research, Development, and Engineering Center's Benet Laboratories (Benet) and the Cerebral Palsy Center for the Disabled (Center), in association with the Department of Neurology at Albany Medical College (AMC). Benet has delivered a working prototype of the device for field testing, in collaboration with Albany Medical College. The Center has identified several children in need of special monitoring and has agreed to pursue commercialization of the device.

  10. Environmental status 2009; Miljoestatus 2009

    Energy Technology Data Exchange (ETDEWEB)

    2009-07-01

    The environment and climate has in recent years received their deserved place high on the public agenda. Still many important issues and contexts make little or no attention in the debates. As environmental directorates one of the most important tasks is to contribute reliable, relevant and understandable information about the state of the environment and development. Environmental status 2009 provides a thematic and comprehensive overview of environmental challenges in Norway. Where are we today, and what are the biggest challenges ahead? What are the national goals? And what have we achieved? The information is based on facts and analysis from their own work and from various research and knowledge communities co-working with the directorate.Climate change has been given much space because it is the biggest threat to the environment. Loss of biological diversity - a major problem compounded by climate change - and the fight against environmental toxins that affect animal and human health, are also high priority. Directorate for Nature Management and Norwegian Pollution Control Authority are responsible for the report and the contents of the chapters on biodiversity and pollution. The chapter on cultural heritage is written by the Cultural Heritage. (AG)

  11. Predictors of Sociometric Status for Low Socioeconomic Status Elementary Mainstreamed Students with and without Special Needs

    Science.gov (United States)

    Baydik, Berrin; Bakkaloglu, Hatice

    2009-01-01

    The purpose of the present study is to compare the sociometric status of low socioeconomic status elementary school students with and without special needs and investigate the effects of different variables (gender, age, physical appearance, social skills, behavior problems, and academic competence) on students' sociometric status. Elementary…

  12. association between health status and visual functioning

    African Journals Online (AJOL)

    2014-01-31

    Jan 31, 2014 ... High blood pressure and abnormal body mass have been observed to correlate negatively with health status. Of interest in this study, is the impact such health status have on visual function indicated by near point of convergence. In this community based cross sectional study, 250 randomly selected ...

  13. Status consumption and poverty in developing countries

    NARCIS (Netherlands)

    van Kempen, L.A.C.M.

    2005-01-01

    This thesis investigates the scope, nature and welfare effects of status consumption by the poor in developing countries, a phenomenon that is virtually unexplored in the development economics literature. It addresses questions such as: why do the poor buy status-intensive goods, while they suffer

  14. Status of the tau one prong problem

    International Nuclear Information System (INIS)

    Hayes, K.G.

    1989-08-01

    The present status of the tau one prong problem is reviewed. Emphasis is placed on recent published branching fraction measurements, the status and implications of tau lifetime measurements, and measurements which constrain the sum of branching fractions to be unity. 29 refs., 10 figs., 2 tabs

  15. Energy status and ovarian follicular development

    NARCIS (Netherlands)

    Meng, Li

    2016-01-01

    Female reproduction is tightly linked to body energy status and it has become increasingly clear that disturbed energy metabolism can negatively affect reproductive performance. Nevertheless, the way how a disturbed energy status affects ovarian follicular reserve as well as follicular

  16. Preliminary Integrated Safety Analysis Status Report

    International Nuclear Information System (INIS)

    Gwyn, D.

    2001-01-01

    This report provides the status of the potential Monitored Geologic Repository (MGR) Integrated Safety Analysis (EA) by identifying the initial work scope scheduled for completion during the ISA development period, the schedules associated with the tasks identified, safety analysis issues encountered, and a summary of accomplishments during the reporting period. This status covers the period from October 1, 2000 through March 30, 2001

  17. Vitamin a status in children with diarrhoea

    OpenAIRE

    Abrol, Pankaj; Mehta, Umesh; Lal, Harbans

    2002-01-01

    Vitamin A status was measured in 50 pre-school children with acute and persistent diarrhoea. It was measured by (a) Fluorometric micromethod and (b) Conjunctival impression cytology (CIC). The results were compared with 25 normal children. Vitamin A status was lower in children with persistent diarrhoea whereas the results were comparable between the children with acute diarrhoea and control subjects.

  18. Socioeconomic status and risk of rheumatoid arthritis

    DEFF Research Database (Denmark)

    Pedersen, Line Merete Blak; Jacobsen, Søren; Klarlund, Mette

    2006-01-01

    To examine whether markers of socioeconomic status (SES) are associated with risk of rheumatoid arthritis (RA), and if so, whether selected lifestyle-related factors could explain this association.......To examine whether markers of socioeconomic status (SES) are associated with risk of rheumatoid arthritis (RA), and if so, whether selected lifestyle-related factors could explain this association....

  19. 49 CFR 1572.105 - Immigration status.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Immigration status. 1572.105 Section 1572.105... ASSESSMENTS Standards for Security Threat Assessments § 1572.105 Immigration status. (a) An individual... to an order of removal under the immigration laws of the United States is not eligible to apply for a...

  20. Preoperative Smoking Status and Postoperative Complications

    DEFF Research Database (Denmark)

    Pedersen, Marie Grønkjær; Eliasen, Marie; Skov-Ettrup, Lise Skrubbeltrang

    2014-01-01

    To systematically review and summarize the evidence of an association between preoperative smoking status and postoperative complications elaborated on complication type.......To systematically review and summarize the evidence of an association between preoperative smoking status and postoperative complications elaborated on complication type....

  1. The impact of migraine on health status

    NARCIS (Netherlands)

    Essink-Bot, M L; van Royen, L; Krabbe, P; Bonsel, G J; Rutten, F F

    PROBLEMS: What is the effect of migraine on health status, defined as the patient's physical, psychological, and social functioning? And, suppose that the health status of migraine sufferers appears to be impaired, to what extent is this a consequence of migraine-associated comorbidity rather than

  2. The impact of migraine on health status

    NARCIS (Netherlands)

    Essink-Bot, M. L.; van Royen, L.; Krabbe, P.; Bonsel, G. J.; Rutten, F. F.

    1995-01-01

    PROBLEMS--What is the effect of migraine on health status, defined as the patient's physical, psychological, and social functioning? And, suppose that the health status of migraine sufferers appears to be impaired, to what extent is this a consequence of migraine-associated comorbidity rather than

  3. Status of (US) High Energy Physics Networking

    International Nuclear Information System (INIS)

    Montgomery, H.E.

    1987-02-01

    The current status of Networking to and between computers used by the High Energy Physics community is discussed. Particular attention is given to developments over the last year and to future prospects. Comparison between the current status and that of two years ago indicates that considerable strides have been made but that much remains to be done to achieve an acceptable level of functionality

  4. Regulatory Circuits Linking Energy Status to Growth

    NARCIS (Netherlands)

    Jansen, W.M.

    2017-01-01

    Plant growth and development critically depend on carbon nutrient status. Over the past years several core regulatory systems that link plant carbon status to growth have emerged. The core regulatory systems studied include the trehalose 6-phosphate (T6P) signaling system and the Target of Rapamycin

  5. Who values the status of the entrepreneur?

    NARCIS (Netherlands)

    van Praag, M.

    2009-01-01

    Parker and Van Praag (2009) showed, based on theory, that the group status of the profession 'entrepreneurship' shapes people's occupational preferences and thus their choice behavior. The current study focuses on the determinants and consequences of the group status of a profession,

  6. Status and neutron scattering experiments at KENS

    International Nuclear Information System (INIS)

    Watanabe, N.; Sasaki, H.; Ishikawa, Y.; Endoh, Y.; Inoue, K.

    1983-01-01

    This paper reports present status of the KENS facility, progress in neutron scattering experiments and instrumental developments, and status of the KENS-I' program. A design study of a high intensity rapid-cycle 800 MeV proton synchrotron for proposed new pulsed neutron (KENS-II) and meson source is also descirbed

  7. Materialism, status consumption, and consumer independence.

    Science.gov (United States)

    Goldsmith, Ronald Earl; Clark, Ronald A

    2012-01-01

    Materialism influences many people. We focus on two aspects of this influence: reactions to prestige products and to the influence of others. A study of 187 U.S. student consumers shows that materialism is positively related to buying products that confer status. In contrast, materialism is negatively related to consumer independence, an enduring tendency to pay minimal attention to the prescribed norms of other consumers and to make product and brand decisions according to personal preferences. Consuming products for status is also negatively related to consumer independence. Moreover, the association between materialism and consumer independence is completely mediated by consuming for status. Materialism urges consumers to be status conscious so that they follow social norms in purchasing, but seeking status through goods is avoided by less materialistic, independent consumers. A second study (n = 258) also using student consumers confirmed these results.

  8. Computer-aided detection in computed tomography colonography. Current status and problems with detection of early colorectal cancer

    International Nuclear Information System (INIS)

    Morimoto, Tsuyoshi; Nakijima, Yasuo; Iinuma, Gen; Arai, Yasuaki; Shiraishi, Junji; Moriyama, Noriyuki; Beddoe, G.

    2008-01-01

    The aim of this study was to evaluate the usefulness of computer-aided detection (CAD) in diagnosing early colorectal cancer using computed tomography colonography (CTC). A total of 30 CTC data sets for 30 early colorectal cancers in 30 patients were retrospectively reviewed by three radiologists. After primary evaluation, a second reading was performed using CAD findings. The readers evaluated each colorectal segment for the presence or absence of colorectal cancer using five confidence rating levels. To compare the assessment results, the sensitivity and specificity with and without CAD were calculated on the basis of the confidence rating, and differences in these variables were analyzed by receiver operating characteristic (ROC) analysis. The average sensitivities for the detection without and with CAD for the three readers were 81.6% and 75.6%, respectively. Among the three readers, only one reader improved sensitivity with CAD compared to that without. CAD decreased specificity in all three readers. CAD detected 100% of protruding lesions but only 69.2% of flat lesions. On ROC analysis, the diagnostic performance of all three readers was decreased by use of CAD. Currently available CAD with CTC does not improve diagnostic performance for detecting early colorectal cancer. An improved CAD algorithm is required for detecting fiat lesions and reducing the false-positive rate. (author)

  9. SEMATECH EUVL mask program status

    Science.gov (United States)

    Yun, Henry; Goodwin, Frank; Huh, Sungmin; Orvek, Kevin; Cha, Brian; Rastegar, Abbas; Kearney, Patrick

    2009-04-01

    As we approach the 22nm half-pitch (hp) technology node, the industry is rapidly running out of patterning options. Of the several lithography techniques highlighted in the International Technology Roadmap for Semiconductors (ITRS), the leading contender for the 22nm hp insertion is extreme ultraviolet lithography (EUVL). Despite recent advances with EUV resist and improvements in source power, achieving defect free EUV mask blank and enabling the EUV mask infrastructure still remain critical issues. To meet the desired EUV high volume manufacturing (HVM) insertion target date of 2013, these obstacles must be resolved on a timely bases. Many of the EUV mask related challenges remain in the pre-competitive stage and a collaborative industry based consortia, such as SEMATECH can play an important role to enable the EUVL landscape. SEMATECH based in Albany, NY is an international consortium representing several of the largest manufacturers in the semiconductor market. Full members include Intel, Samsung, AMD, IBM, Panasonic, HP, TI, UMC, CNSE (College of Nanoscience and Engineering), and Fuller Road Management. Within the SEMATECH lithography division a major thrust is centered on enabling the EUVL ecosystem from mask development, EUV resist development and addressing EUV manufacturability concerns. An important area of focus for the SEMATECH mask program has been the Mask Blank Development Center (MBDC). At the MBDC key issues in EUV blank development such as defect reduction and inspection capabilities are actively pursued together with research partners, key suppliers and member companies. In addition the mask program continues a successful track record of working with the mask community to manage and fund critical mask tools programs. This paper will highlight recent status of mask projects and longer term strategic direction at the MBDC. It is important that mask technology be ready to support pilot line development HVM by 2013. In several areas progress has been

  10. Current status of diuretic renography

    International Nuclear Information System (INIS)

    O'Reilly, P.H.

    1987-01-01

    Percutaneous antegrade perfusion studies constitute a valuable contribution to the investigation of obstructive uropathy. In 1978, the first report of application of diuretic renogram techniques to this problem appeared in the literature. This was the first systematic report of a standardized protocol to be applied to a specific surgical problem. The purpose of the procedure, as with perfusion pressure-flow studies, is to help distinguish between a dilated urinary tract that is obstructed and requires surgery and a nonobstructed system in which urographic dilation and stasis mimic obstruction, but no genuine impedance to urine flow exists, and surgery is not required. The technique provides dual information. It gives quantitative data on individual renal function that perfusion pressure-flow studies do not, and it gives time-activity curves reflecting the urodynamics through the individual upper urinary tracts at normal and high urinary flow rates. In the early days, this information was obtained from probe studies, but the procedure is now almost exclusively performed using the gamma camera, images from which give additional information on the site of any suspected obstruction. In some ways, the development of diuretic renography and that of perfusion pressure-flow studies have proceeded in a competitive fashion, both attempting to answer the same questions by different means. In practice, however, the two tests would be regarded as complementary, as will be shown later in this chapter. The following sections describe the technique of diuretic renography, its current clinical application and status in surgical and nuclear medicine practice, and its role in comparison with other available tests for management of the dilated upper urinary tract

  11. GRACE Status at Mission End

    Science.gov (United States)

    Tapley, B. D.; Flechtner, F. M.; Watkins, M. M.; Bettadpur, S. V.

    2017-12-01

    The twin satellites of the Gravity Recovery and Climate Experiment (GRACE) were launched on March 17, 2002 and have operated for nearly 16 years. The mission objectives are to observe the spatial and temporal variations of the Earth's mass through its effects on the gravity field at the GRACE satellite altitude. The mass changes observed are related to both the changes within the solid earth and the change within and between the Erath system components. A significant cause of the time varying mass is water motion and the GRACE mission has provided a continuous decade long measurement sequence which characterizes the seasonal cycle of mass transport between the oceans, land, cryosphere and atmosphere; its inter-annual variability; and the climate driven secular, or long period, mass transport signals. The fifth reanalysis on the mission data set, the RL05 data, were released in mid-2013. With the planned launch of GRACE Follow-On in early 2018, plans are underway for a reanalysis that will be consistent with the GRACE FO processing standards. The mission is entering the final phases of its operation life with mission end expected to occur in early 2018. The current mission operations strategy emphasizes extending the mission lifetime to obtain an overlap with the GRACE FO. This presentation will review the mission status and the projections for mission lifetime, describe the current operations philosophy and its impact on the science data, discuss the issues related to achieving the GRACE and GRACE FO connection and discuss issues related to science data products during this phase of the mission period.

  12. Stone composition and metabolic status.

    Science.gov (United States)

    Bibilash, B S; Vijay, Adarsh; Fazil Marickar, Y M

    2010-06-01

    This paper aims to study the correlation between biochemical risk factors of the stone former and the type of oxalate stone formed, namely calcium oxalate monohydrate (COM) and calcium oxalate dehydrate (COD). A retrospective study of 487 patients who had been attending the urinary stone clinic, Trivandrum during 1998-2007 was conducted. The stones retrieved from them were subjected to chemical analysis and FTIR spectrographic analysis. They were categorized into COM, COD, mixed COM+COD and others. Of 142 pure calcium oxalate stone patients, 87 were predominantly COM stone formers and 55 COD stone formers. Their metabolic status of 24 h urine and serum was assessed. The values of urine calcium, phosphorus, uric acid, magnesium, creatinine, oxalate, citric acid, sodium and potassium, serum values of calcium, phosphorus, uric acid, magnesium and creatinine and calculated values of creatinine clearance, tubular reabsorption of phosphate, calcium magnesium ratio and calcium oxalate ratio were recorded. Comparison was made between the COM stone group and the COD stone group. Patients forming COM stones had significantly higher mean values for urine calcium (P stone forming patients. All other values failed to show significant difference. Patients, with higher urine oxalate, formed COM stones. Those with low magnesium (which is an inhibitor) formed more of COD stones. Urine calcium was high in both groups without showing significant variation from the mean. In patients with high calcium-oxalate and calcium-magnesium ratios, there is higher chance of forming a COD stone than COM. Identification of the crystallization pattern of the calcium stone will help in selecting treatment modalities.

  13. Genetic mutations associated with status epilepticus.

    Science.gov (United States)

    Bhatnagar, M; Shorvon, S

    2015-08-01

    This paper reports the results of a preliminary search of the literature aimed at identifying the genetic mutations reported to be strongly associated with status epilepticus. Genetic mutations were selected for inclusion if status epilepticus was specifically mentioned as a consequence of the mutation in standard genetic databases or in a case report or review article. Mutations in 122 genes were identified. The genetic mutations identified were found in only rare conditions (sometimes vanishingly rare) and mostly in infants and young children with multiple other handicaps. Most of the genetic mutations can be subdivided into those associated with cortical dysplasias, inborn errors of metabolism, mitochondrial disease, or epileptic encephalopathies and childhood syndromes. There are no identified 'pure status epilepticus genes'. The range of genes underpinning status epilepticus differs in many ways from the range of genes underpinning epilepsy, which suggests that the processes underpinning status epilepticus differ from those underpinning epilepsy. It has been frequently postulated that status epilepticus is the result of a failure of 'seizure termination mechanisms', but the wide variety of genes affecting very diverse biochemical pathways identified in this survey makes any unitary cause unlikely. The genetic influences in status epilepticus are likely to involve a wide range of mechanisms, some related to development, some to cerebral energy production, some to diverse altered biochemical pathways, some to transmitter and membrane function, and some to defects in networks or systems. The fact that many of the identified genes are involved with cerebral development suggests that status epilepticus might often be a system or network phenomenon. To date, there are very few genes identified which are associated with adult-onset status epilepticus (except in those with preexisting neurological damage), and this is disappointing as the cause of many adult

  14. Primary status, complementary status, and organizational survival in the U.S. venture capital industry.

    Science.gov (United States)

    Bothner, Matthew S; Kim, Young-Kyu; Lee, Wonjae

    2015-07-01

    We introduce a distinction between two kinds of status and examine their effects on the exit rates of organizations investing in the U.S. venture capital industry. Extending past work on status-based competition, we start with a simple baseline: we describe primary status as a network-related signal of an organization's quality in a leadership role, that is, as a function of the degree to which an organization leads others that are themselves well regarded as lead organizations in the context of investment syndicates. Combining Harary's (1959) image of the elite consultant with Goffman's (1956) concept of "capacity-esteem," we then discuss complementary status as an affiliation-based signal of an organization's quality in a supporting role. We measure complementary status as a function of the extent to which an organization is invited into syndicates by well-regarded lead organizations-that is, by those possessing high levels of primary status. Findings show that, conditioning on primary status, complementary status reduces the rate at which venture capital organizations exit the industry. Consistent with the premise that these kinds of status correspond to different roles and market identities, we also find that complementary status attenuates (and ultimately reverses) the otherwise favorable effect of primary status on an organization's life chances. Theoretically and methodologically oriented scope conditions, as well as implications for future research, are discussed. Copyright © 2015 Elsevier Inc. All rights reserved.

  15. Spread of status value: Rewards and the creation of status characteristics.

    Science.gov (United States)

    Harkness, Sarah K

    2017-01-01

    Rewards have social significance and are highly esteemed objects, but what does their ownership signify to others? Prior work has demonstrated it may be possible for these rewards to spread their status to those who possess them, such that individuals gain or lose status and influence by virtue of the rewards they display. Yet, is this spread enough to produce entirely new status characteristics by virtue of their association with rewards? I propose a theoretical extension of the spread of status value theory and offer an experimental test considering whether the status value conveyed by rewards spreads to a new, nominal characteristic of those who come to possess these objects. The results indicate that states of a nominal characteristic do gain or lose status value and behavioral influence through their association with differentially valued rewards. Thus, rewards can create new status characteristics with resulting behavioral expectations. Copyright © 2016 Elsevier Inc. All rights reserved.

  16. Hierarchy and social status in Budongo chimpanzees.

    Science.gov (United States)

    Newton-Fisher, Nicholas E

    2004-04-01

    The status hierarchy is fundamental in the lives of male chimpanzees. This study describes the dominance interactions and social status among adult male chimpanzees of the Sonso community in the Budongo Forest Reserve, Uganda, during the period that they were first studied (1994 and 1995). Social dominance is typically measured using the behaviour of either the subordinate or the dominant individual, but a relationship is dependent on the behaviour of both parties and this study explicitly used both subordinate and dominant behaviours to investigate the status hierarchy. Among adult males of the Sonso community, agonistic interactions occurred at a low rate and pant-grunts were rare, but males could be ranked into separate hierarchies of agonistic dominance and pant-grunting (labelled 'respect') using ratios of behaviour performed/behaviour received. These hierarchies were combined to form a single hierarchy of social status that divided the males among five distinct status levels. The highest status level was held by an alliance between two males who replaced the previous alpha male during the first part of the study. Neither male in this alliance partnership pant-grunted to the other, although the reason for cooperative behaviour was unclear. Although the nominally beta male was treated as such by other adult males, he achieved surprisingly little mating success. Budongo Forest chimpanzees do not warrant the sometimes-expressed view that they are non-aggressive and peaceable and the broad pattern of their status interactions matches with that seen in other chimpanzee populations.

  17. Decoupling social status and status certainty effects on health in macaques: a network approach

    Directory of Open Access Journals (Sweden)

    Jessica J. Vandeleest

    2016-09-01

    Full Text Available Background Although a wealth of literature points to the importance of social factors on health, a detailed understanding of the complex interplay between social and biological systems is lacking. Social status is one aspect of social life that is made up of multiple structural (humans: income, education; animals: mating system, dominance rank and relational components (perceived social status, dominance interactions. In a nonhuman primate model we use novel network techniques to decouple two components of social status, dominance rank (a commonly used measure of social status in animal models and dominance certainty (the relative certainty vs. ambiguity of an individual’s status, allowing for a more complex examination of how social status impacts health. Methods Behavioral observations were conducted on three outdoor captive groups of rhesus macaques (N = 252 subjects. Subjects’ general physical health (diarrhea was assessed twice weekly, and blood was drawn once to assess biomarkers of inflammation (interleukin-6 (IL-6, tumor necrosis factor-alpha (TNF-α, and C-reactive protein (CRP. Results Dominance rank alone did not fully account for the complex way that social status exerted its effect on health. Instead, dominance certainty modified the impact of rank on biomarkers of inflammation. Specifically, high-ranked animals with more ambiguous status relationships had higher levels of inflammation than low-ranked animals, whereas little effect of rank was seen for animals with more certain status relationships. The impact of status on physical health was more straightforward: individuals with more ambiguous status relationships had more frequent diarrhea; there was marginal evidence that high-ranked animals had less frequent diarrhea. Discussion Social status has a complex and multi-faceted impact on individual health. Our work suggests an important role of uncertainty in one’s social status in status-health research. This work also

  18. The influence of status on satisfaction with relative rewards

    DEFF Research Database (Denmark)

    Albrecht, Konstanze; Essen, Emma von; Falk, Armin

    2014-01-01

    This study investigates how induced relative status affects satisfaction with different relative payoffs. We find that participants with lower status are more satisfied with disadvantageous payoff inequalities than equal or higher status participants. In contrast, when receiving an advantageous...... payoff, status does not affect satisfaction. Our findings suggest that relative social status has important implications for the acceptance of income inequalities....

  19. The influence of status on satisfaction with relative rewards

    Science.gov (United States)

    Albrecht, Konstanze; von Essen, Emma; Fliessbach, Klaus; Falk, Armin

    2013-01-01

    This study investigates how induced relative status affects satisfaction with different relative payoffs. We find that participants with lower status are more satisfied with disadvantageous payoff inequalities than equal or higher status participants. In contrast, when receiving an advantageous payoff, status does not affect satisfaction. Our findings suggest that relative social status has important implications for the acceptance of income inequalities. PMID:24198802

  20. Status of radiation-based measurement technology

    International Nuclear Information System (INIS)

    Moon, B. S.; Lee, J. W.; Chung, C. E.; Hong, S. B.; Kim, J. T.; Park, W. M.; Kim, J. Y.

    1999-03-01

    This report describes the status of measurement equipment using radiation source and new technologies in this field. This report includes the development status in Korea together with a brief description of the technology development and application status in ten countries including France, America, and Japan. Also this report describes technical factors related to radiation-based measurement and trends of new technologies. Measurement principles are also described for the equipment that is widely used among radiation-based measurement, such as level measurement, density measurement, basis weight measurement, moisture measurement, and thickness measurement. (author). 7 refs., 2 tabs., 21 figs