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Sample records for undertaken measurements revealed

  1. ROMANIA MEASURES UNDERTAKEN TO OVERCOME THE CRISIS MACROECONOMIC POLICIES THROUGH

    Directory of Open Access Journals (Sweden)

    MUNGIU-PUPĂZAN MARIANA CLAUDIA

    2013-02-01

    Full Text Available This research paper is intended to be an analysis of the measures taken by the Romanian economic recoverythrough levers it has at hand, namely macroeconomic policies. Current financial and economic crisis appears to beunprecedented in the last half century. Whether it's a financial crisis or an economic one, we can talk about theeconomy installing a pronounced instability, uncertainty and insecurity about the future. There is a significantdecrease in the volume of transactions on the stock exchange, lack of trust in the financial system, a disturbance ofmarket mechanisms.The crisis has caused and continues to cause effects in various sectors of the economy, includingjob losses. Following the severe global economic problems, the crisis has spread rapidly in all areas.States have beenthe subject of theoretical dispute for decades, and these arguments have been rekindled with interventions bygovernments of countries affected by the recent crisis.

  2. [Strategies for protecting the elderly from the health-risks of heat-waves: measures undertaken in Italy in the summer of 2004].

    Science.gov (United States)

    de Martino, Annamaria; Vasselli, Stefania; D'Argenio, Paolo

    2005-01-01

    Heat waves constitute an important public health problem because of their potential serious health impact on vulnerable populations such as the elderly and individuals living in poor health, socioeconomic, cultural or environmental conditions. The summer of 2003 was the hottest summer, with respect to both minimum and maximum temperatures, of the last fifty years. During that summer, an increased mortality was found especially in the elderly population = 75 years. The Ministry of Health therefore released guidelines for the regions and other local authorities, regarding the measures be undertaken in order to safeguard the elderly and other vulnerable populations from the health risks associated with heat waves. Subsequently, a survey was performed to collect information regarding the projects put into practice in the summer of 2004 by the various regions and local authorities. The aim of the study was to promote a comparison and sharing of appropriately documented experiences. This article classifies and describes the various interventions that were put into practice.

  3. Total hip replacement for Mseleni Joint Disease undertaken in a ...

    African Journals Online (AJOL)

    Total hip replacement for Mseleni Joint Disease undertaken in a rural hospital: five-year follow-up. Abstract. Objective: The objective of this project was to ascertain whether it is reasonable to perform specialist surgery for Mseleni Joint Disease (MJD) in a rural hospital by assessing the medium- term outcome of surgery for ...

  4. Reduction of occupational exposures in PWR power plants - actions undertaken

    International Nuclear Information System (INIS)

    Jeanson, P.

    1983-01-01

    The reduction of doses to nuclear power plant workers is a permanent aim of Electricite de France. Many actions are undertaken simultaneously some of them jointly with the Commissariat a l'Energie Atomique. The theoretical studies bear mainly on the formation and transfer of corrosion and fission products in the primary circuit of PWRs and on the procedures to lower the deposited activity. The practical studies bear on the design of materials and buildings and the rules of installation as well as on the chemical conditioning of the primary fluid. They also bear on the conditions of maintenance of all the components; for the main ones, special tools are designed. Finally, operating a daily dosimetry makes it possible to know the distribution of collective doses better and therefore to judiciously direct the actions to be undertaken [fr

  5. Online survey of insolvency professionals undertaken for TSO. Final report.

    OpenAIRE

    Tribe, John; Purdy, David

    2014-01-01

    The London Gazette was first published as\\ud The Oxford Gazette in 1665. It is Great Britain’s\\ud oldest continuously-published newspaper and\\ud it has a long history of publishing insolvencyrelated\\ud information.\\ud This survey was commissioned in 2012 by\\ud TSO - publishers of The Gazette series - to\\ud investigate IP use of insolvency information in\\ud their publications.\\ud Our analysis relies heavily upon an online\\ud survey undertaken by Kingston Law School\\ud during February-March 201...

  6. Lyin' eyes: ocular-motor measures of reading reveal deception.

    Science.gov (United States)

    Cook, Anne E; Hacker, Douglas J; Webb, Andrea K; Osher, Dahvyn; Kristjansson, Sean D; Woltz, Dan J; Kircher, John C

    2012-09-01

    Our goal was to evaluate an alternative to current methods for detecting deception in security screening contexts. We evaluated a new cognitive-based test of deception that measured participants' ocular-motor responses (pupil responses and reading behaviors) while they read and responded to statements on a computerized questionnaire. In Experiment 1, participants from a university community were randomly assigned to either a "guilty" group that committed one of two mock crimes or an "innocent" group that only learned about the crime. Participants then reported for testing, where they completed the computer-administered questionnaire that addressed their possible involvement in the crimes. Experiment 2 also manipulated participants' incentive to pass the test and difficulty of statements on the test. In both experiments, guilty participants had increased pupil responses to statements answered deceptively; however, they spent less time fixating on, reading, and rereading those statements than statements answered truthfully. These ocular-motor measures were optimally weighted in a discrimination function that correctly classified 85% of participants as either guilty or innocent. Findings from Experiment 2 indicated that group discrimination was improved with greater incentives to pass the test and the use of statements with simple syntax. The present findings suggest that two cognitive processes are involved in deception-vigilance and strategy-and that these processes are reflected in different ocular-motor measures. The ocular-motor test reported here represents a new approach to detecting deception that may fill an important need in security screening contexts.

  7. Lyin’ Eyes: Ocular-motor Measures of Reading Reveal Deception

    Science.gov (United States)

    Cook, Anne E.; Hacker, Douglas J.; Webb, Andrea K.; Osher, Dahvyn; Kristjansson, Sean; Woltz, Dan J.; Kircher, John C.

    2013-01-01

    Our goal was to evaluate an alternative to current methods for detecting deception in security screening contexts. We evaluated a new cognitive-based test of deception that measured participants’ ocular-motor responses (pupil responses and reading behaviors) while they read and responded to statements on a computerized questionnaire. In Experiment 1, participants from a university community were randomly assigned to either a “guilty” group that committed one of two mock crimes or an “innocent” group that only learned about the crime. Participants then reported for testing, where they completed the computer-administered questionnaire that addressed their possible involvement in the crimes. Experiment 2 also manipulated participants’ incentive to pass the test and difficulty of statements on the test. In both experiments, guilty participants had increased pupil responses to statements answered deceptively; however, they spent less time fixating on, reading, and re-reading those statements than statements answered truthfully. These ocular-motor measures were optimally weighted in a discrimination function that correctly classified 85% of participants as either guilty or innocent. Findings from Experiment 2 indicated that group discrimination was improved with greater incentives to pass the test and the use of statements with simple syntax. The present findings suggest that two cognitive processes are involved in deception -- vigilance and strategy -- and that these processes are reflected in different ocular-motor measures. The ocular-motor test reported here represents a new approach to detecting deception that may fill an important need in security screening contexts. PMID:22545928

  8. Report to the Fort Belknap Community Council on the work undertaken during the summer, 1979

    Energy Technology Data Exchange (ETDEWEB)

    Wehrenberg, J.P.; Ballard, J.H.; Pfouts, R.P.

    1979-01-01

    Results are presented of a gravity survey undertaken to determine the potential for oil and gas extraction on the Fort Belknap Indian Reservation. Two hundred forty-eight gravity measurements were taken and at least one major anomaly was found. Analysis of available surface and subsurface information suggests that there is a limited potential for oil but a somewhat better potential for the development of gas. Commercial development of coal is not likely, but there is at least one small coalfield that may be exploited for local use. Bentonite presents the best option for commercial development.

  9. 10 CFR 745.119 - Research undertaken without the intention of involving human subjects.

    Science.gov (United States)

    2010-01-01

    ... human subjects. 745.119 Section 745.119 Energy DEPARTMENT OF ENERGY PROTECTION OF HUMAN SUBJECTS § 745.119 Research undertaken without the intention of involving human subjects. In the event research is undertaken without the intention of involving human subjects, but it is later proposed to involve human...

  10. 15 CFR 27.119 - Research undertaken without the intention of involving human subjects.

    Science.gov (United States)

    2010-01-01

    ... intention of involving human subjects. 27.119 Section 27.119 Commerce and Foreign Trade Office of the Secretary of Commerce PROTECTION OF HUMAN SUBJECTS § 27.119 Research undertaken without the intention of involving human subjects. In the event research is undertaken without the intention of involving human...

  11. 14 CFR 1230.119 - Research undertaken without the intention of involving human subjects.

    Science.gov (United States)

    2010-01-01

    ... of involving human subjects. 1230.119 Section 1230.119 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION PROTECTION OF HUMAN SUBJECTS § 1230.119 Research undertaken without the intention of involving human subjects. In the event research is undertaken without the intention of involving...

  12. 28 CFR 46.119 - Research undertaken without the intention of involving human subjects.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Research undertaken without the intention of involving human subjects. 46.119 Section 46.119 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PROTECTION OF HUMAN SUBJECTS § 46.119 Research undertaken without the intention of involving...

  13. 49 CFR 11.119 - Research undertaken without the intention of involving human subjects.

    Science.gov (United States)

    2010-10-01

    ... involving human subjects. 11.119 Section 11.119 Transportation Office of the Secretary of Transportation PROTECTION OF HUMAN SUBJECTS § 11.119 Research undertaken without the intention of involving human subjects. In the event research is undertaken without the intention of involving human subjects, but it is...

  14. 45 CFR 690.119 - Research undertaken without the intention of involving human subjects.

    Science.gov (United States)

    2010-10-01

    ... involving human subjects. 690.119 Section 690.119 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION PROTECTION OF HUMAN SUBJECTS § 690.119 Research undertaken without the intention of involving human subjects. In the event research is undertaken without the intention...

  15. 22 CFR 225.119 - Research undertaken without the intention of involving human subjects.

    Science.gov (United States)

    2010-04-01

    ... involving human subjects. 225.119 Section 225.119 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT PROTECTION OF HUMAN SUBJECTS § 225.119 Research undertaken without the intention of involving human subjects. In the event research is undertaken without the intention of involving human subjects, but it is...

  16. 16 CFR 1028.119 - Research undertaken without the intention of involving human subjects.

    Science.gov (United States)

    2010-01-01

    ... involving human subjects. 1028.119 Section 1028.119 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL PROTECTION OF HUMAN SUBJECTS § 1028.119 Research undertaken without the intention of involving human subjects. In the event research is undertaken without the intention of involving human subjects...

  17. 7 CFR 1c.119 - Research undertaken without the intention of involving human subjects.

    Science.gov (United States)

    2010-01-01

    ... human subjects. 1c.119 Section 1c.119 Agriculture Office of the Secretary of Agriculture PROTECTION OF HUMAN SUBJECTS § 1c.119 Research undertaken without the intention of involving human subjects. In the event research is undertaken without the intention of involving human subjects, but it is later proposed...

  18. Self-reported ballet classes undertaken at age 10-12 years and hip bone mineral density in later life.

    Science.gov (United States)

    Khan, K M; Bennell, K L; Hopper, J L; Flicker, L; Nowson, C A; Sherwin, A J; Crichton, K J; Harcourt, P R; Wark, J D

    1998-01-01

    The major effect of weightbearing exercise on adult bone mass may be exerted during childhood. We examined the relationship between reported hours of ballet classes per week undertaken as a child and adult bone mineral density (BMD) at the hip, spine, and forearm. We performed a retrospective cohort study in 99 female retired dancers (mean age 51 years, SD 14 years) and 99 normal controls, derived from a twin study, matched hierarchically for age, height, weight and menopausal status. Starting age of ballet was recalled and weekly hours of ballet as a child was self-reported on two occasions. BMD was measured using dualenergy X-ray absorptiometry and reported as a Z-score. Self-reported hours of ballet class undertaken per week at each age between 10 and 12 years was positively associated with a difference in BMD between dancers and controls at both the femoral neck site (beta = 0.73, p = 0.001) and the total hip site (beta = 0.55, p ballet), measures of menstrual disturbance (age of menarche, history of irregular menses), dietary history (calcium intake as a child, adolescent or adult) or lifestyle factors (lifetime smoking, lifetime alcohol). Although starting age of ballet was negatively associated with weight-adjusted within-pair hip BMD difference, it was no longer associated after adjustment for weekly hours of ballet. There was no relationship between hours of ballet undertaken as a child and differences in BMD at the lumbar spine or upper limb, at any age. Our data suggest that classical ballet classes undertaken between the ages of 10 and 12 years are independently and positively associated with a difference in hip BMD between dancers and controls. The findings are consistent with the hypothesis that this age range identifies a stage of development when the proximal femur is particularly responsive to weightbearing exercise.

  19. 34 CFR 97.119 - Research undertaken without the intention of involving human subjects.

    Science.gov (United States)

    2010-07-01

    ... human subjects. 97.119 Section 97.119 Education Office of the Secretary, Department of Education PROTECTION OF HUMAN SUBJECTS Federal Policy for the Protection of Human Subjects (Basic ED Policy for Protection of Human Research Subjects) § 97.119 Research undertaken without the intention of involving human...

  20. 45 CFR 46.119 - Research undertaken without the intention of involving human subjects.

    Science.gov (United States)

    2010-10-01

    ... involving human subjects. 46.119 Section 46.119 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION PROTECTION OF HUMAN SUBJECTS Basic HHS Policy for Protection of Human Research Subjects § 46.119 Research undertaken without the intention of involving human subjects. In the event...

  1. 40 CFR 26.119 - Research undertaken without the intention of involving human subjects.

    Science.gov (United States)

    2010-07-01

    ... intention of involving human subjects. 26.119 Section 26.119 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PROTECTION OF HUMAN SUBJECTS Basic EPA Policy for Protection of Subjects in Human... human subjects. In the event research is undertaken without the intention of involving human subjects...

  2. Fibrinogen adsorption mechanisms at the gold substrate revealed by QCM-D measurements and RSA modeling.

    Science.gov (United States)

    Kubiak, Katarzyna; Adamczyk, Zbigniew; Cieśla, Michał

    2016-03-01

    Adsorption kinetics of fibrinogen at a gold substrate at various pHs was thoroughly studied using the QCM-D method. The experimental were interpreted in terms of theoretical calculations performed according to the random sequential adsorption model (RSA). In this way, the hydration functions and water factors of fibrinogen monolayers were quantitatively evaluated at various pHs. It was revealed that for the lower range of fibrinogen coverage the hydration function were considerably lower than previously obtained for the silica sensor [33]. The lower hydration of fibrinogen monolayers on the gold sensor was attributed to its higher roughness. However, for higher fibrinogen coverage the hydration functions for both sensors became identical exhibiting an universal behavior. By using the hydration functions, the fibrinogen adsorption/desorption runs derived from QCM-D measurements were converted to the Γd vs. the time relationships. This allowed to precisely determine the maximum coverage that varied between 1.6mgm(-2) at pH 3.5 and 4.5mgm(-2) at pH 7.4 (for ionic strength of 0.15M). These results agree with theoretical eRSA modeling and previous experimental data derived by using ellipsometry, OWLS and TIRF. Various fibrinogen adsorption mechanisms were revealed by exploiting the maximum coverage data. These results allow one to develop a method for preparing fibrinogen monolayers of well-controlled coverage and molecule orientation. Copyright © 2015 Elsevier B.V. All rights reserved.

  3. Assessing exposure to 3-MCPD from bakery products based on monitoring studies undertaken throughout Poland.

    Science.gov (United States)

    Starski, Andrzej; Jedra, Małgorzata; Gawarska, Halina; Postupolski, Jacek

    2013-01-01

    The compound 3-monochloropropano-1,2-diol, (3-MCPD) is a contaminant found in foodstuffs that arises during food processing and storage. Conditions condusive to the former are low pH and a high temperature and it can also be formed during manufacturing, ie. food processing. Those favouring the latter are dampness, raised temperatures, packaging conditions and storage duration. For the first time, high levels of 3-MCPD have been reported in soy sauces and hydrolysate products of vegetable protein manufactured through using acid hydrolysis. Animal studies on rats and mice have found that 3-MCPD is a carcinogen, however it is not genotoxic. To determine 3-MCPD levels in bakery products currently on the market and to estimate the resulting exposure to the those consumer groups most vulnerable. Results from a two year assessment of this contaminant are so presented. Concentrations of 3-MCPD were measured in 244 samples of bakery foodstuff products found on the market which included; sponge cake, biscuits, cakes, crackers, breadsticks and rusks. Sampling was undertaken by the State Sanitary Inspectorate and analyses were performed by an accredited Gas Chromatography Mass Spectrometry (GC/MS) method. The exposure was assessed by comparing the accepted Tolerable Daily Intake (TDI) for 3-MCPD with the different conditions it occurred in, the consumption of 3-MCPD in the aforementioned foodstuffs and the various consumer groups. Levels of 3-MCPD that exceeded the limits of quantification in the studied foodstuffs were found in 91 out of 244 samples, (ie. 37.3%). These samples included 11 sponge cakes (11.3%), 27 biscuits (55.2%), 10 crackers (8.33%), 17 breadsticks (8.93%), 21 rusks (63.6%) and 5 cakes (3.13%). The highest numbers of samples containing more than 10 (> or = 10) microg/ kg of 3-MCPD were successively found in the following; breadsticks (79%), biscuits (75%), rusks (33%), crackers (33%), cakes (31%), biscuits (24%) and sponge cakes (4%). In 60 samples (24

  4. Hydrophobic attraction as revealed by AFM force measurements and molecular dynamics simulation.

    Science.gov (United States)

    Fa, Keqing; Nguyen, Anh V; Miller, Jan D

    2005-07-14

    Spherical calcium dioleate particles ( approximately 10 mum in diameter) were used as AFM (atomic force microscope) probes to measure interaction forces of the collector colloid with calcite and fluorite surfaces. The attractive AFM force between the calcium dioleate sphere and the fluorite surface is strong and has a longer range than the DLVO (Derjaguin-Landau-Verwey-Overbeek) prediction. The AFM force between the calcium dioleate sphere and the mineral surfaces does not agree with the DLVO prediction. Consideration of non-DLVO forces, including the attractive hydrophobic force and the repulsive hydration force, was necessary to explain the experimental results. The non-DLVO interactions considered were justified by the different interfacial water structures at calcite- and fluorite-water interfaces as revealed by the numerical computation experiments with molecular dynamics simulation.

  5. New Aspects of Photocurrent Generation at Graphene pn Junctions Revealed by Ultrafast Optical Measurements

    Science.gov (United States)

    Aivazian, Grant; Sun, Dong; Jones, Aaron; Ross, Jason; Yao, Wang; Cobden, David; Xu, Xiaodong

    2012-02-01

    The remarkable electrical and optical properties of graphene make it a promising material for new optoelectronic applications. However, one important, but so far unexplored, property is the role of hot carriers in charge and energy transport at graphene interfaces. Here we investigate the photocurrent (PC) dynamics at a tunable graphene pn junction using ultrafast scanning PC microscopy. Pump-probe measurements show a temperature dependent relaxation time of photogenerated carriers that increases from 1.5ps at 290K to 4ps at 20K; while the amplitude of the PC is independent of the lattice temperature. These observations imply that it is hot carriers, not phonons, which dominate ultrafast energy transport. Gate dependent measurements show many interesting features such as pump induced saturation, enhancement, and sign reversal of probe generated PC. These observations reveal that the underlying PC mechanism is a combination of the thermoelectric and built-in electric field effects. Our results enhance the understanding of non-equilibrium electron dynamics, electron-electron interactions, and electron-phonon interactions in graphene. They also determine fundamental limits on ultrafast device operation speeds (˜500 GHz) for graphene-based photodetectors.

  6. Revealing time-unlocked brain activity from MEG measurements by common waveform estimation.

    Directory of Open Access Journals (Sweden)

    Yusuke Takeda

    Full Text Available Brain activities related to cognitive functions, such as attention, occur with unknown and variable delays after stimulus onsets. Recently, we proposed a method (Common Waveform Estimation, CWE that could extract such brain activities from magnetoencephalography (MEG or electroencephalography (EEG measurements. CWE estimates spatiotemporal MEG/EEG patterns occurring with unknown and variable delays, referred to here as unlocked waveforms, without hypotheses about their shapes. The purpose of this study is to demonstrate the usefulness of CWE for cognitive neuroscience. For this purpose, we show procedures to estimate unlocked waveforms using CWE and to examine their role. We applied CWE to the MEG epochs during Go trials of a visual Go/NoGo task. This revealed unlocked waveforms with interesting properties, specifically large alpha oscillations around the temporal areas. To examine the role of the unlocked waveform, we attempted to estimate the strength of the brain activity of the unlocked waveform in various conditions. We made a spatial filter to extract the component reflecting the brain activity of the unlocked waveform, applied this spatial filter to MEG data under different conditions (a passive viewing, a simple reaction time, and Go/NoGo tasks, and calculated the powers of the extracted components. Comparing the powers across these conditions suggests that the unlocked waveforms may reflect the inhibition of the task-irrelevant activities in the temporal regions while the subject attends to the visual stimulus. Our results demonstrate that CWE is a potential tool for revealing new findings of cognitive brain functions without any hypothesis in advance.

  7. High-resolution Bio-Argo and Argo Measurements to Reveal Specific Oceanic Processes.

    Science.gov (United States)

    Poteau, A.; Claustre, H.; Briggs, N.; D'Ortenzio, F.; Schmechtig, C.; Prieur, L. M.; Boss, E.

    2016-02-01

    Together with temperature and salinity measurements, Bio-Argo profiling floats now measure a significant range of biogeochemical (e.g. O2, NO3) and bio-optical variables (Chla, backscattering coefficient and radiometry). To transmit the very large amount of data acquired by this new generation of floats, it was required to substitute the Argos telemetry (Argo program) with iridium telemetry. The obvious consequence is not only a much greater flexibly on data transmission but also on data acquisition thanks to the two-way communication allowed by iridium. Our group has now deployed and managed over 100 Bio-Argo floats of this type. In particular we have set up high-resolution mode of acquisition for certain periods of time or for dedicated portions of the water column. Here we illustrate with three examples the potential of conducting high-resolution measurement to identify and explore certain oceanic processes. (1) High resolution measurements of pressure, temperature and salinity (every 2 s) when the float is finishing its ascent (without any pump action) in the upper 10 m layer are analyzed with respect to sea state. We particularly focus on the study of the speed anomaly as compared to a nominal speed expected for a calm sea state. By comparison between speed anomaly of a float in the Mediterranean Sea and concurrent sea state measurements by a weather buoy in the same area, we suggest that float behaviour can be an indicator of sea state. (2) Each year, in response to springtime phytoplankton blooms, the resolution of bio-optical variables (backscattering and Chla) in the top 1000 m was increased to at least 1 m (every 10 s) for all floats in the North Atlantic and Southern Ocean. This resolution allowed accurate estimation of the concentration of large phytoplankton aggregates and revealed systematic differences in bulk aggregate sinking rate between ocean basins. (3) Finally we continuously record all the variables at a 10 min resolution during the float

  8. Micrometeorological Measurements Reveal Large Nitrous Oxide Losses during Spring Thaw in Alberta

    Directory of Open Access Journals (Sweden)

    Thomas K. Flesch

    2018-03-01

    Full Text Available Agricultural soils in Canada have been observed to emit a large pulse of nitrous oxide (N2O gas during the spring thaw, representing a large percentage of the annual emissions. We report on three years of spring thaw N2O flux measurements taken at three Alberta agricultural sites: a crop production site (Crop, cattle winter-feeding site (WF, and a cattle winter-grazing site (WG. Soil fluxes were calculated with a micrometeorological technique based on the vertical gradient in N2O concentration above each site measured with an open-path (line-averaging FTIR gas detector. The Crop and WG sites showed a clear N2O emission pulse lasting 10 to 25 days after thawing began. During this pulse there was a strong diurnal cycle in emissions that paralleled the cycle in near-surface soil temperature. The emission pulse was less pronounced at the WF site. The average spring thaw losses (over 25 to 31 days were 5.3 (Crop, 7.0 (WF, and 8.0 (WG kg N2O-N ha−1, representing 1 to 3.5% of the annual nitrogen input to the sites. These large losses are higher than found in most previous western Canadian studies, and generally higher than the annual losses estimated from the Intergovernmental Panel on Climate Change and Canadian National Inventory Report calculations. The high N2O losses may be explained by high soil nitrate levels which promoted rapid denitrification during thawing. The application of a high resolution (temporal micrometeorological technique was critical to revealing these losses.

  9. Long term kinetic measurements revealing precision and general performance of surface plasmon resonance biosensors.

    Science.gov (United States)

    Steinicke, Franziska; Oltmann-Norden, Imke; Wätzig, Hermann

    2017-08-01

    This work presents an extensive parameter list that facilitates a survey of biosensor performance using Biacore instruments for kinetic binding studies. Six long term measurements were performed using a strongly interacting antigen-antibody (β2 microglobulin) system. Both Single Cycle Kinetic (SCK) and Multi Cycle Kinetic (MCK) were executed each with five different analyte concentrations. The overall comparison of the long term monitored parameters, like the dissociation constant (K D with approximately 3-6% relative percental standard deviation), the association and dissociation rate constants (k a , k d ), the analyte binding capacity (R max ), chi 2 and the sum of the absolute values of the residuals, revealed the delicate factors that make the system performance vulnerable. The main influential factors on kinetic performance were the regeneration conditions, the quality of the sensor surface, the usage time and alteration of the sensor surface, the dilution series and the number of run cycles (about 250-600 per chip). Moreover the direct comparison of MCK and SCK uncovered distinct differences in the accuracy of the K D values. The study of sensor chips from two manufacturers showed distinct differences in the precision of the data. Using control charts for the surveillance of these parameters contributes to an overall better system performance. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. Automated gray level index measurements reveal only minor cytoarchitectonic changes of Brodmann area 9 in schizophrenia.

    Science.gov (United States)

    Tepest, Ralf; Vogeley, Kai; Viebahn, Bettina; Schneider-Axmann, Thomas; Honer, William G; Falkai, Peter

    2008-07-15

    Using an automatized gray level index (GLI) method, we recently found cytoarchitectonic abnormalities in schizophrenia in Brodmann area 10 (BA10) [Vogeley, K., Tepest, R., Schneider-Axmann, T., Hutte, H., Zilles, K., Honer, W.G., Falkai, P., 2003. Automated image analysis of disturbed cytoarchitecture in Brodmann area 10 in schizophrenia, Schizophrenia Research 62, 133-140]. As another potential key region involved in the pathophysiology of schizophrenia, we have now investigated BA9 in the same sample consisting of 20 schizophrenic cases and 20 controls. The GLI value represents the area-percentage covered by perikarya in measuring fields of microscopic images. BA9 was analyzed with respect to the factors diagnosis and gender for six different compartments approximately corresponding to the neocortical layers. The main result in BA9 was a significant interaction of diagnosis and gender for GLI in layers IV and V on the left side. Subsequent analyses separately performed concerning gender revealed a significant GLI increase in layer V on the left side in male patients compared with controls. However, after an adjustment of error probabilities for multiple testing, differences did not reach significance. No GLI difference was observed in the sample between diagnostic groups for females and between the diagnostic groups in general. Comparisons with our BA10 results suggest that cytoarchitectural changes relevant to schizophrenia appear different in various Brodmann areas. Since increases in GLI were found only in selected layers (V and VI) of BA9, these findings do not support a generalized neuropil reduction across all cortical layers.

  11. Redox-controlled backbone dynamics of human cytochrome c revealed by 15N NMR relaxation measurements

    International Nuclear Information System (INIS)

    Sakamoto, Koichi; Kamiya, Masakatsu; Uchida, Takeshi; Kawano, Keiichi; Ishimori, Koichiro

    2010-01-01

    Research highlights: → The dynamic parameters for the backbone dynamics in Cyt c were determined. → The backbone mobility of Cyt c is highly restricted due to the covalently bound heme. → The backbone mobility of Cyt c is more restricted upon the oxidation of the heme. → The redox-dependent dynamics are shown in the backbone of Cyt c. → The backbone dynamics of Cyt c would regulate the electron transfer from Cyt c. -- Abstract: Redox-controlled backbone dynamics in cytochrome c (Cyt c) were revealed by 2D 15 N NMR relaxation experiments. 15 N T 1 and T 2 values and 1 H- 15 N NOEs of uniformly 15 N-labeled reduced and oxidized Cyt c were measured, and the generalized order parameters (S 2 ), the effective correlation time for internal motion (τ e ), the 15 N exchange broadening contributions (R ex ) for each residue, and the overall correlation time (τ m ) were estimated by model-free dynamics formalism. These dynamic parameters clearly showed that the backbone dynamics of Cyt c are highly restricted due to the covalently bound heme that functions as the stable hydrophobic core. Upon oxidation of the heme iron in Cyt c, the average S 2 value was increased from 0.88 ± 0.01 to 0.92 ± 0.01, demonstrating that the mobility of the backbone is further restricted in the oxidized form. Such increases in the S 2 values were more prominent in the loop regions, including amino acid residues near the thioether bonds to the heme moiety and positively charged region around Lys87. Both of the regions are supposed to form the interaction site for cytochrome c oxidase (CcO) and the electron pathway from Cyt c to CcO. The redox-dependent mobility of the backbone in the interaction site for the electron transfer to CcO suggests an electron transfer mechanism regulated by the backbone dynamics in the Cyt c-CcO system.

  12. International medical electives undertaken by Australian medical students: current trends and future directions.

    Science.gov (United States)

    Law, Iain R; Worley, Paul S; Langham, Freya J

    2013-04-01

    To estimate the proportion of students in Australian medical schools who undertake international medical electives (IMEs), particularly in developing countries, and to ascertain which medical schools provide predeparture training and postelective debriefing. Extraction of data on the number of students undertaking electives from the Medical Schools Outcomes Database (MSOD) for the 2013s 2006 to 2010; and interviews with the directors of each medical school in Australia in May to July 2012 to ascertain the availability of predeparture training and postelective debriefing. The proportion of medical students undertaking IMEs overall and within developing countries and the proportion of medical schools with optional and mandatory predeparture training and postelective debriefing. Fifty-three per cent of graduate-entry (GE) program students and 35% of high-school entry (HSE) program students undertook IMEs. Fifty-nine per cent of electives undertaken by GE program students were in developing countries, compared with 56% for HSE program students. Predeparture training was offered by 12 of the 16 Australian medical schools, but it was mandatory in only six. Only eight schools offer postelective debriefing. A large proportion of Australian medical students undertake IMEs in developing countries. However, a considerable proportion of students do not undertake formal preparation for, or reflection on, their experiences. Predeparture training and postelective debriefing should be scaled up across Australian medical schools to provide students with the guidance and support to maximise the benefits and minimise risks associated with undertaking IMEs in developing countries.

  13. An economic analysis of a major bio-fuel program undertaken by OECD countries

    International Nuclear Information System (INIS)

    2002-01-01

    Biofuels such as ethanol and bio-diesel are creating a new demand for agricultural output and for agriculture land in Canada. However, the participation of other large countries with a large demand potential is necessary for bio-fuels to have a significant impact on the price of grains and oilseeds. This paper quantified the potential impact that a major bio-fuel program initiated by OECD countries has on grain and oilseed prices. The program was initiated for the period 1999 to 2006. There is considerable interest by Canadian producers to stimulate grain and oilseed prices by increasing demand of biofuels. This renewable energy source produces fewer greenhouse gas emissions than petroleum products. The analysis presented in this paper only considered ethanol from corn or wheat and bio-diesel from vegetable oils. It also focused only on the use of bio-fuels in the OECD transportation sector. The analysis was undertaken with AGLINK, a multi-commodity multi-country policy-specific dynamic model of the international agricultural markets built by the OECD with member countries. It was shown that the increase in world and domestic prices for grains and vegetable oils will remain strong, particularly toward 2006. It was also shown that a major bio-fuel program for all OECD countries would be beneficial to Canadian agriculture. It was concluded that ultimately, an increase in OECD bio-fuels usage has a direct impact on the demand for grains and oilseeds which are important feed-stocks in biofuel production. The analysis presumes an increase in renewable fuel use, but does not consider factors such as financial incentives and regulatory requirements that could bring about this increase. 7 refs., 6 tabs., 4 figs

  14. In situ measurements reveal extremely low pH in soil

    DEFF Research Database (Denmark)

    Nielsen, Knud Erik; Loibide, Amaia Irixar; Nielsen, Lars Peter

    2017-01-01

    We measured pH in situ in the top organic soil horizons in heathland and pine forest and found values between 2.6 and 3.2. This was 0.5e0.8 units lower than concurrent laboratory pH measurements of the same soil, which raises questions about the interpretation of pH measurements. We propose...... that the higher pH recorded by standard laboratory methods may be due to buffering ions from soil biota released from drying, grinding and rewetting of soil samples, whereas the in situ pH reflects the correct level of acidification....

  15. Revealing the connectivity of groundwater and surface water using electromagnetic induction measurements

    Science.gov (United States)

    Binley, A. M.; McLachlan, P.; Chambers, J. E.; Uhlemann, S.

    2016-12-01

    It is now widely recognised that hydrological and biogeochemical processes that occur at the interface of groundwater (GW) and surface water (SW) can have a significant impact on catchment water quality and ecosystem health. Significant heterogeneity in the fabric of the subsurface at the GW-SW interface can lead to complex fluid flow pathways, both of which can exert a strong control on biogeochemical cycling. Revealing such heterogeneity remains a challenge because of the limitations of traditional field experimental processes. Such traditional techniques are often invasive, which often prevents their use in ecologically sensitive environments. Furthermore, they are often limited to localised characterisation. Studies to date have thus focussed on relatively small (easily accessible) stream environments, at short reach, or plot, scales. There is a clear demand for techniques that can capture the heterogeneity of sediments and pore fluids over larger scales. Geophysical methods may offer valuable information at such scales, particularly when used in combination with traditional sampling approaches. The value of electrical methods for revealing detailed information about the heterogeneity of sediments at the GW-SW interface has been demonstrated, and in a few studies such methods have assisted tracer tests in mapping the solute pathways. However, most investigations have been confined to relatively small scale (tens of metres). There is growing (and renewed) interest in the use of frequency domain electromagnetic induction (EMI) techniques in hydrogeophysics. At the GW-SW interface these methods allow rapid, non-invasive exploration of the top few metres. Relatively recent technological developments have provided multi-coil instrumentation, permitting rapid assessment of electrical conductivity at multiple depths of investigation. Here, we demonstrate the effectiveness of EMI for revealing the heterogeneity of sediments and flow pathways at the GW-SW interface. We

  16. Monitoring and evaluation of disaster response efforts undertaken by local health departments: a rapid realist review.

    Science.gov (United States)

    Gossip, Kate; Gouda, Hebe; Lee, Yong Yi; Firth, Sonja; Bermejo, Raoul; Zeck, Willibald; Jimenez Soto, Eliana

    2017-06-29

    Local health departments are often at the forefront of a disaster response, attending to the immediate trauma inflicted by the disaster and also the long term health consequences. As the frequency and severity of disasters are projected to rise, monitoring and evaluation (M&E) efforts are critical to help local health departments consolidate past experiences and improve future response efforts. Local health departments often conduct M&E work post disaster, however, many of these efforts fail to improve response procedures. We undertook a rapid realist review (RRR) to examine why M&E efforts undertaken by local health departments do not always result in improved disaster response efforts. We aimed to complement existing frameworks by focusing on the most basic and pragmatic steps of a M&E cycle targeted towards continuous system improvements. For these purposes, we developed a theoretical framework that draws on the quality improvement literature to 'frame' the steps in the M&E cycle. This framework encompassed a M&E cycle involving three stages (i.e., document and assess, disseminate and implement) that must be sequentially completed to learn from past experiences and improve future disaster response efforts. We used this framework to guide our examination of the literature and to identify any context-mechanism-outcome (CMO) configurations which describe how M&E may be constrained or enabled at each stage of the M&E cycle. This RRR found a number of explanatory CMO configurations that provide valuable insights into some of the considerations that should be made when using M&E to improve future disaster response efforts. Firstly, to support the accurate documentation and assessment of a disaster response, local health departments should consider how they can: establish a culture of learning within health departments; use embedded training methods; or facilitate external partnerships. Secondly, to enhance the widespread dissemination of lessons learned and facilitate

  17. Describing qualitative research undertaken with randomised controlled trials in grant proposals: a documentary analysis

    Science.gov (United States)

    2014-01-01

    Background There is growing recognition of the value of conducting qualitative research with trials in health research. It is timely to reflect on how this qualitative research is presented in grant proposals to identify lessons for researchers and research commissioners. As part of a larger study focusing on how to maximise the value of undertaking qualitative research with trials, we undertook a documentary analysis of proposals of funded studies. Methods Using the metaRegister of Controlled Trials (mRCT) database we identified trials funded in the United Kingdom, ongoing between 2001 and 2010, and reporting the use of qualitative research. We requested copies of proposals from lead researchers. We extracted data from the proposals using closed and open questions, analysed using descriptive statistics and content analysis respectively. Results 2% (89/3812) of trials in the mRCT database described the use of qualitative research undertaken with the trial. From these 89 trials, we received copies of 36 full proposals, of which 32 met our inclusion criteria. 25% used less than a single paragraph to describe the qualitative research. The aims of the qualitative research described in these proposals focused mainly on the intervention or trial conduct. Just over half (56%) of the proposals included an explicit rationale for conducting the qualitative research with the trial, the most frequent being to optimise implementation into clinical practice or to interpret trial findings. Key information about methods, expertise and resources was missing in a large minority of proposals, in particular sample size, type of analysis, and non-personnel resources. 28% specifically stated that qualitative researchers would conduct the qualitative research. Conclusions Our review of proposals of successfully funded studies identified good practice but also identified limited space given to describing the qualitative research, with an associated lack of attention to the rationale for

  18. Describing qualitative research undertaken with randomised controlled trials in grant proposals: a documentary analysis.

    Science.gov (United States)

    Drabble, Sarah J; O'Cathain, Alicia; Thomas, Kate J; Rudolph, Anne; Hewison, Jenny

    2014-02-18

    There is growing recognition of the value of conducting qualitative research with trials in health research. It is timely to reflect on how this qualitative research is presented in grant proposals to identify lessons for researchers and research commissioners. As part of a larger study focusing on how to maximise the value of undertaking qualitative research with trials, we undertook a documentary analysis of proposals of funded studies. Using the metaRegister of Controlled Trials (mRCT) database we identified trials funded in the United Kingdom, ongoing between 2001 and 2010, and reporting the use of qualitative research. We requested copies of proposals from lead researchers. We extracted data from the proposals using closed and open questions, analysed using descriptive statistics and content analysis respectively. 2% (89/3812) of trials in the mRCT database described the use of qualitative research undertaken with the trial. From these 89 trials, we received copies of 36 full proposals, of which 32 met our inclusion criteria. 25% used less than a single paragraph to describe the qualitative research. The aims of the qualitative research described in these proposals focused mainly on the intervention or trial conduct. Just over half (56%) of the proposals included an explicit rationale for conducting the qualitative research with the trial, the most frequent being to optimise implementation into clinical practice or to interpret trial findings. Key information about methods, expertise and resources was missing in a large minority of proposals, in particular sample size, type of analysis, and non-personnel resources. 28% specifically stated that qualitative researchers would conduct the qualitative research. Our review of proposals of successfully funded studies identified good practice but also identified limited space given to describing the qualitative research, with an associated lack of attention to the rationale for doing the qualitative research and

  19. Revealed Comparative Advantage and the Alternatives as Measures of International Specialization

    DEFF Research Database (Denmark)

    Laursen, Keld

    2015-01-01

    discussion focuses on the properties of RSCA and empirical evidence, based on the Jarque-Bera test for normality of the regression error terms, using both the RCA and RSCA indices. We compare RSCA to other measures of international trade specialization including the Michaely index, the Contribution to Trade...

  20. Measurement of refractive index by nanoparticle tracking analysis reveals heterogeneity in extracellular vesicles

    Directory of Open Access Journals (Sweden)

    Chris Gardiner

    2014-11-01

    Full Text Available Introduction: Optical techniques are routinely used to size and count extracellular vesicles (EV. For comparison of data from different methods and laboratories, suitable calibrators are essential. A suitable calibrator must have a refractive index (RI as close to that of EV as possible but the RI of EV is currently unknown. To measure EV, RI requires accurate knowledge of size and light scattering. These are difficult to measure as most EVs cannot be resolved by light microscopy and their diameter is smaller than the wavelength of visible light. However, nanoparticle tracking analysis (NTA provides both size and relative light scattering intensity (rLSI values. We therefore sought to determine whether it was possible to use NTA to measure the RI of individual EVs. Methods: NTA was used to measure the rLSI and size of polystyrene and silica microspheres of known size and RI (1.470 and 1.633, respectively and of EV isolated from a wide range of cells. We developed software, based on Mie scattering code, to calculate particle RI from the rLSI data. This modelled theoretical scattering intensities for polystyrene and silica microspheres of known size (100 and 200 nm and RI. The model was verified using data from the polystyrene and silica microspheres. Size and rLSI data for each vesicle were processed by the software to generate RI values. Results: The following modal RI measurements were obtained: fresh urinary EV 1.374, lyophilised urinary EV 1.367, neuroblastoma EV 1.393, blood EV 1.398, EV from activated platelets 1.390, small placental EV 1.364–1.375 and 1.398–1.414 for large placental EV (>200 nm. Large placental EV had a significantly higher RI than small placental EV (p1.40 were observed for some large (>200 nm microvesicles. Conclusion: This method for measuring EV RI will be useful for developing appropriate calibrators for EV measurement.

  1. Direct measurements reveal non-Markovian fluctuations of DNA threading through a solid-state nanopore

    OpenAIRE

    Bell, Nicholas A. W.; Keyser, Ulrich F.

    2016-01-01

    The threading of a polymer chain through a small pore is a classic problem in polymer dynamics and underlies nanopore sensing technology. However important experimental aspects of the polymer motion in a solid-state nanopore, such as an accurate measurement of the velocity variation during translocation, have remained elusive. In this work we analysed the translocation through conical quartz nanopores of a 7 kbp DNA double-strand labelled with six markers equally spaced along its contour. The...

  2. Soil gases and SAR measurements reveal hidden faults on the sliding flank of Mt. Etna (Italy)

    Science.gov (United States)

    Bonforte, Alessandro; Federico, Cinzia; Giammanco, Salvatore; Guglielmino, Francesco; Liuzzo, Marco; Neri, Marco

    2013-02-01

    From October 2008 to November 2009, soil CO2, radon and structural field surveys were performed on Mt. Etna, in order to acquire insights into active tectonic structures in a densely populated sector of the south-eastern flank of the volcano, which is involved in the flank dynamics, as highlighted by satellite data (InSAR). The studied area extends about 150 km2, in a sector of the volcano where InSAR results detected several lineaments that were not well-defined from previous geological surveys. In order to validate and better constrain these features with ground data evidences, soil CO2 and soil radon measurements were performed along transects roughly orthogonal to the newly detected faults, with measurement points spaced about 100 m. In each transect, the highest CO2 values were found very close to the lineaments evidenced by InSAR observations. Anomalous soil CO2 and radon values were also measured at old eruptive fractures. In some portions of the investigated area soil gas anomalies were rather broad over transects, probably suggesting a complex structural framework consisting of several parallel volcano-tectonic structures, instead of a single one. Soil gas measurements proved particularly useful in areas at higher altitude on Mt. Etna (i.e. above 900 m asl), where InSAR results are not very informative/are fairly limited, and allowed recognizing the prolongation of some tectonic lineaments towards the summit of the volcano. At a lower altitude on the volcanic edifice, soil gas anomalies define the active structures indicated by InSAR results prominently, down to almost the coastline and through the northern periphery of the city of Catania. Coupling InSAR with soil gas prospecting methods has thus proved to be a powerful tool in detecting hidden active structures that do not show significant field evidences.

  3. A Comparative Analysis of Initiatives and Adaptation Measures to Climate Change Undertaken in Poland and Western Europe

    Directory of Open Access Journals (Sweden)

    Michalak Dorota

    2016-12-01

    Full Text Available Climate change is one of the greatest contemporary threats to our planet’s environmental, social and economic well-being, accompanied by major changes in life support systems on Earth, where the far-reaching effects will be felt in the coming decades. The Earth’s climate is warming rapidly due to emissions of greenhouse gases caused by human activities such as burning fossil fuels and deforestation.

  4. Multigap Superconductivity in the Ferromagnetic Superconductor UCoGe Revealed by Thermal Conductivity Measurements

    Directory of Open Access Journals (Sweden)

    Ludovic Howald

    2014-01-01

    Full Text Available We performed thermal conductivity measurements on a single crystal of the ferromagnetic superconductor UCoGe under magnetic field. Two different temperature dependencies of the thermal conductivity are observed, for H→∥b→: linear at low magnetic field and quadratic for magnetic field larger than 1 Tesla. At the same field value, a plateau appears in the field dependency of the residual term of thermal conductivity. Such observations suggest a multigap superconductivity with a line of nodes in the superconducting gap.

  5. One-neutron removal measurement reveals 24O as a new doubly magic nucleus.

    Science.gov (United States)

    Kanungo, R; Nociforo, C; Prochazka, A; Aumann, T; Boutin, D; Cortina-Gil, D; Davids, B; Diakaki, M; Farinon, F; Geissel, H; Gernhäuser, R; Gerl, J; Janik, R; Jonson, B; Kindler, B; Knöbel, R; Krücken, R; Lantz, M; Lenske, H; Litvinov, Y; Lommel, B; Mahata, K; Maierbeck, P; Musumarra, A; Nilsson, T; Otsuka, T; Perro, C; Scheidenberger, C; Sitar, B; Strmen, P; Sun, B; Szarka, I; Tanihata, I; Utsuno, Y; Weick, H; Winkler, M

    2009-04-17

    The first measurement of the momentum distribution for one-neutron removal from (24)O at 920A MeV performed at GSI, Darmstadt is reported. The observed distribution has a width (FWHM) of 99 +/- 4 MeV/c in the projectile rest frame and a one-neutron removal cross section of 63 +/- 7 mb. The results are well explained with a nearly pure 2s_{1/2} neutron spectroscopic factor of 1.74 +/- 0.19 within the eikonal model. This large s-wave probability shows a spherical shell closure thereby confirming earlier suggestions that (24)O is a new doubly magic nucleus.

  6. Revealing strong bias in common measures of galaxy properties using new inclination-independent structures

    Science.gov (United States)

    Devour, Brian M.; Bell, Eric F.

    2017-06-01

    Accurate measurement of galaxy structures is a prerequisite for quantitative investigation of galaxy properties or evolution. Yet, the impact of galaxy inclination and dust on commonly used metrics of galaxy structure is poorly quantified. We use infrared data sets to select inclination-independent samples of disc and flattened elliptical galaxies. These samples show strong variation in Sérsic index, concentration and half-light radii with inclination. We develop novel inclination-independent galaxy structures by collapsing the light distribution in the near-infrared on to the major axis, yielding inclination-independent 'linear' measures of size and concentration. With these new metrics we select a sample of Milky Way analogue galaxies with similar stellar masses, star formation rates, sizes and concentrations. Optical luminosities, light distributions and spectral properties are all found to vary strongly with inclination: When inclining to edge-on, r-band luminosities dim by >1 magnitude, sizes decrease by a factor of 2, 'dust-corrected' estimates of star formation rate drop threefold, metallicities decrease by 0.1 dex and edge-on galaxies are half as likely to be classified as star forming. These systematic effects should be accounted for in analyses of galaxy properties.

  7. Long-Term Measurements of Human Inflammatory Cytokines Reveal Complex Baseline Variations between Individuals.

    Science.gov (United States)

    Wu, Danlu; Dinh, Trinh L; Bausk, Bruce P; Walt, David R

    2017-12-01

    Comprehensive characterization of the healthy human proteome baseline is essential for personalized medicine. Baseline data are necessary to understand the variation between individuals, as well as longitudinal variation within individuals. Many important protein biomarkers, such as cytokines, exist at extremely low or undetectable levels in the healthy state. This paper describes results from a 14-week study of healthy human subjects using ultrasensitive single-molecule array (Simoa) assays to measure both intra and intersubject variation of 15 cytokines. The results show a wide variation in the ranges of some cytokines between individuals and demonstrate that individual baseline values will be essential for predicting disease presence and progression. Although all of the studied cytokines demonstrated high temporal stability (or low intrasubject variation) over the entire study period, there were two distinct groups of cytokines that demonstrated either high (IL-8, IFN-γ, IL-2, IL-6, and IL-1β) or low (IL-15, TNF-α, IL-12 p70, IL-17A, GM-CSF, IL-12 p40, IL-10, IL-7, IL-1α, and IL-5) subject-to-subject variation. This work demonstrates that ultrasensitive assays are essential for characterizing human cytokines in healthy subjects. The results show that some cytokines vary by more than two orders of magnitude between individuals, making it an imperative to obtain individual baseline measurements if they are to play a role in health and disease diagnosis. Copyright © 2017 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.

  8. Equilibrium moisture content of radiata pine at elevated temperature and pressure reveals measurement challenges

    DEFF Research Database (Denmark)

    Pearson, Hamish; Gabbitas, Brian; Ormarsson, Sigurdur

    2012-01-01

    moisture contents were attributed to condensation of liquid water on the specimen with subsequent evaporation at a rate that was too slow for the moisture content to reach equilibrium before it was measured. Reliable EMC data at elevated temperatures require (1) tight process control of experimental......Relatively few studies have been performed on the equilibrium moisture content (EMC) of wood under conditions of elevated temperature and pressure. Eight studies indicated that EMC near saturation decreased between 100 and 150 °C, whilst five studies indicated that EMC increased. The aim...... of this study was to identify the likely source of the disagreement using radiata pine (Pinus radiata D. Don) sapwood which was conditioned to a moisture content of around 3 % and then exposed for 1 h at 150 °C and relative humidities of either 50, 70 or 90 %. Mean values of EMC, obtained through in situ...

  9. Planetary science. Low-altitude magnetic field measurements by MESSENGER reveal Mercury's ancient crustal field.

    Science.gov (United States)

    Johnson, Catherine L; Phillips, Roger J; Purucker, Michael E; Anderson, Brian J; Byrne, Paul K; Denevi, Brett W; Feinberg, Joshua M; Hauck, Steven A; Head, James W; Korth, Haje; James, Peter B; Mazarico, Erwan; Neumann, Gregory A; Philpott, Lydia C; Siegler, Matthew A; Tsyganenko, Nikolai A; Solomon, Sean C

    2015-05-22

    Magnetized rocks can record the history of the magnetic field of a planet, a key constraint for understanding its evolution. From orbital vector magnetic field measurements of Mercury taken by the MErcury Surface, Space ENvironment, GEochemistry, and Ranging (MESSENGER) spacecraft at altitudes below 150 kilometers, we have detected remanent magnetization in Mercury's crust. We infer a lower bound on the average age of magnetization of 3.7 to 3.9 billion years. Our findings indicate that a global magnetic field driven by dynamo processes in the fluid outer core operated early in Mercury's history. Ancient field strengths that range from those similar to Mercury's present dipole field to Earth-like values are consistent with the magnetic field observations and with the low iron content of Mercury's crust inferred from MESSENGER elemental composition data. Copyright © 2015, American Association for the Advancement of Science.

  10. Field measurement of beef pen manure methane and nitrous oxide reveals a surprise for inventory calculations.

    Science.gov (United States)

    Redding, M R; Devereux, J; Phillips, F; Lewis, R; Naylor, T; Kearton, T; Hill, C J; Weidemann, S

    2015-05-01

    Few data exist on direct greenhouse gas emissions from pen manure at beef feedlots. However, emission inventories attempt to account for these emissions. This study used a large chamber to isolate NO and CH emissions from pen manure at two Australian commercial beef feedlots (stocking densities, 13-27 m head) and related these emissions to a range of potential emission control factors, including masses and concentrations of volatile solids, NO, total N, NH, and organic C (OC), and additional factors such as total manure mass, cattle numbers, manure pack depth and density, temperature, and moisture content. Mean measured pen NO emissions were 0.428 kg ha d (95% confidence interval [CI], 0.252-0.691) and 0.00405 kg ha d (95% CI, 0.00114-0.0110) for the northern and southern feedlots, respectively. Mean measured CH emission was 0.236 kg ha d (95% CI, 0.163-0.332) for the northern feedlot and 3.93 kg ha d (95% CI, 2.58-5.81) for the southern feedlot. Nitrous oxide emission increased with density, pH, temperature, and manure mass, whereas negative relationships were evident with moisture and OC. Strong relationships were not evident between NO emission and masses or concentrations of NO or total N in the manure. This is significant because many standard inventory calculation protocols predict NO emissions using the mass of N excreted by the animal. Copyright © by the American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America, Inc.

  11. Simple pain measures reveal psycho-social pathology in patients with Crohn's disease.

    Science.gov (United States)

    Odes, Shmuel; Friger, Michael; Sergienko, Ruslan; Schwartz, Doron; Sarid, Orly; Slonim-Nevo, Vered; Singer, Terri; Chernin, Elena; Vardi, Hillel; Greenberg, Dan; Israel Ibd Research Nucleus

    2017-02-14

    To determine whether pain has psycho-social associations in adult Crohn's disease (CD) patients. Patients completed demographics, disease status, Patient Harvey-Bradshaw Index (P-HBI), Short Form Health Survey (SF-36), Short Inflammatory Bowel Disease Questionnaire (SIBDQ), and five socio-psychological questionnaires: Brief Symptom Inventory, Brief COPE Inventory, Family Assessment Device, Satisfaction with Life Scale, and Work Productivity and Activity Impairment Questionnaire. Pain sub-scales in P-HBI, SF-36 and SIBDQ measures were recoded into 4 identical scores for univariate and multinomial logistic regression analysis of associations with psycho-social variables. The cohort comprised 594 patients, mean age 38.6 ± 14.8 years, women 52.5%, P-HBI 5.76 ± 5.15. P-HBI, SF-36 and SIBDQ broadly agreed in their assessment of pain intensity. More severe pain was significantly associated with female gender, low socio-economic status, unemployment, Israeli birth and smoking. Higher pain scores correlated positively with psychological stress, dysfunctional coping strategies, poor family relationships, absenteeism, presenteeism, productivity loss and activity impairment and all WPAI sub-scores. Patients exhibiting greater satisfaction with life had less pain. The regression showed increasing odds ratios for psychological stress (lowest 2.26, highest 12.17) and female gender (highest 3.19) with increasing pain. Internet-recruited patients were sicker and differed from hardcopy questionnaire patients in their associations with pain. Pain measures in P-HBI, SF-36 and SIBDQ correlate with psycho-social pathology in CD. Physicians should be aware also of these relationships in approaching CD patients with pain.

  12. Comparison of Dolphins' Body and Brain Measurements with Four Other Groups of Cetaceans Reveals Great Diversity.

    Science.gov (United States)

    Ridgway, Sam H; Carlin, Kevin P; Van Alstyne, Kaitlin R; Hanson, Alicia C; Tarpley, Raymond J

    2016-01-01

    We compared mature dolphins with 4 other groupings of mature cetaceans. With a large data set, we found great brain diversity among 5 different taxonomic groupings. The dolphins in our data set ranged in body mass from about 40 to 6,750 kg and in brain mass from 0.4 to 9.3 kg. Dolphin body length ranged from 1.3 to 7.6 m. In our combined data set from the 4 other groups of cetaceans, body mass ranged from about 20 to 120,000 kg and brain mass from about 0.2 to 9.2 kg, while body length varied from 1.21 to 26.8 m. Not all cetaceans have large brains relative to their body size. A few dolphins near human body size have human-sized brains. On the other hand, the absolute brain mass of some other cetaceans is only one-sixth as large. We found that brain volume relative to body mass decreases from Delphinidae to a group of Phocoenidae and Monodontidae, to a group of other odontocetes, to Balaenopteroidea, and finally to Balaenidae. We also found the same general trend when we compared brain volume relative to body length, except that the Delphinidae and Phocoenidae-Monodontidae groups do not differ significantly. The Balaenidae have the smallest relative brain mass and the lowest cerebral cortex surface area. Brain parts also vary. Relative to body mass and to body length, dolphins also have the largest cerebellums. Cortex surface area is isometric with brain size when we exclude the Balaenidae. Our data show that the brains of Balaenidae are less convoluted than those of the other cetaceans measured. Large vascular networks inside the cranial vault may help to maintain brain temperature, and these nonbrain tissues increase in volume with body mass and with body length ranging from 8 to 65% of the endocranial volume. Because endocranial vascular networks and other adnexa, such as the tentorium cerebelli, vary so much in different species, brain size measures from endocasts of some extinct cetaceans may be overestimates. Our regression of body length on endocranial

  13. Urban eddy covariance measurements reveal significant missing NOx emissions in Central Europe.

    Science.gov (United States)

    Karl, T; Graus, M; Striednig, M; Lamprecht, C; Hammerle, A; Wohlfahrt, G; Held, A; von der Heyden, L; Deventer, M J; Krismer, A; Haun, C; Feichter, R; Lee, J

    2017-05-30

    Nitrogen oxide (NO x ) pollution is emerging as a primary environmental concern across Europe. While some large European metropolitan areas are already in breach of EU safety limits for NO 2 , this phenomenon does not seem to be only restricted to large industrialized areas anymore. Many smaller scale populated agglomerations including their surrounding rural areas are seeing frequent NO 2 concentration violations. The question of a quantitative understanding of different NO x emission sources is therefore of immanent relevance for climate and air chemistry models as well as air pollution management and health. Here we report simultaneous eddy covariance flux measurements of NO x , CO 2 , CO and non methane volatile organic compound tracers in a city that might be considered representative for Central Europe and the greater Alpine region. Our data show that NO x fluxes are largely at variance with modelled emission projections, suggesting an appreciable underestimation of the traffic related atmospheric NO x input in Europe, comparable to the weekend-weekday effect, which locally changes ozone production rates by 40%.

  14. In God we trust? Neural measures reveal lower social conformity among non-religious individuals.

    Science.gov (United States)

    Thiruchselvam, Ravi; Gopi, Yashoda; Kilekwang, Leonard; Harper, Jessica; Gross, James J

    2017-06-01

    Even in predominantly religious societies, there are substantial individual differences in religious commitment. Why is this? One possibility is that differences in social conformity (i.e. the tendency to think and behave as others do) underlie inclination towards religiosity. However, the link between religiosity and conformity has not yet been directly examined. In this study, we tested the notion that non-religious individuals show dampened social conformity, using both self-reported and neural (EEG-based ERPs) measures of sensitivity to others' influence. Non-religious vs religious undergraduate subjects completed an experimental task that assessed levels of conformity in a domain unrelated to religion (i.e. in judgments of facial attractiveness). Findings showed that, although both groups yielded to conformity pressures at the self-report level, non-religious individuals did not yield to such pressures in their neural responses. These findings highlight a novel link between religiosity and social conformity, and hold implications for prominent theories about the psychological functions of religion. © The Author (2017). Published by Oxford University Press.

  15. Revealing the link between licensed outlets and violence: counting venues versus measuring alcohol availability.

    Science.gov (United States)

    Liang, Wenbin; Chikritzhs, Tanya

    2011-09-01

    Associations between alcohol-related harms and numbers of outlets at the neighbourhood level have been demonstrated; however, the degree to which alcohol consumption or sales plays a part in levels of violence is not clear. This has contributed to uncertainty regarding the actual mechanisms by which outlet density may influence levels of violence. This ecological cross-sectional study investigated the effect of outlet numbers and alcohol sales on the risk of assault in Western Australia. For 2000/2001, information on type, number and wholesale alcohol purchases of all licensed outlets in operation, police-reported assault offences, socioeconomic/demographic data were obtained from official sources. Multivariate negative binomial regression was applied to at local government area level in order to assess associations between outlet density, alcohol sales and violence occurring in both licensed and domestic settings. Average alcohol sales volume per off-site outlet was significantly associated with all measures of assault. Numbers of on-site outlets significantly predicted violence with the exception of assaults occurring at residential premises. Alcohol sales from off-site outlets predicted violence occurring at on-site outlets. The link between on-site outlets and violence may be primarily underpinned by negative amenity effects while off-site outlet effects occur via increased availability. Alcohol sales volumes from off-site outlets influence levels of violence, which occur at both licensed and residential settings. The substantial and wide-ranging effects of liquor stores on alcohol-related harms may have been underestimated in the literature and by policy makers. © 2011 Australasian Professional Society on Alcohol and other Drugs.

  16. Multiple measures reveal antiretroviral adherence successes and challenges in HIV-infected Ugandan children.

    Directory of Open Access Journals (Sweden)

    Jessica E Haberer

    Full Text Available Adherence to HIV antiretroviral therapy (ART among children in developing settings is poorly understood.To understand the level, distribution, and correlates of ART adherence behavior, we prospectively determined monthly ART adherence through multiple measures and six-monthly HIV RNA levels among 121 Ugandan children aged 2-10 years for one year. Median adherence levels were 100% by three-day recall, 97.4% by 30-day visual analog scale, 97.3% by unannounced pill count/liquid formulation weights, and 96.3% by medication event monitors (MEMS. Interruptions in MEMS adherence of ≥ 48 hours were seen in 57.0% of children; 36.3% had detectable HIV RNA at one year. Only MEMS correlated significantly with HIV RNA levels (r = -0.25, p = 0.04. Multivariable regression found the following to be associated with <90% MEMS adherence: hospitalization of child (adjusted odds ratio [AOR] 3.0, 95% confidence interval [CI] 1.6-5.5; p = 0.001, liquid formulation use (AOR 1.4, 95%CI 1.0-2.0; p = 0.04, and caregiver's alcohol use (AOR 3.1, 95%CI 1.8-5.2; p<0.0001. Child's use of co-trimoxazole (AOR 0.5, 95%CI 0.4-0.9; p = 0.009, caregiver's use of ART (AOR 0.6, 95%CI 0.4-0.9; p = 0.03, possible caregiver depression (AOR 0.6, 95%CI 0.4-0.8; p = 0.001, and caregiver feeling ashamed of child's HIV status (AOR 0.5, 95%CI 0.3-0.6; p<0.0001 were protective against <90% MEMS adherence. Change in drug manufacturer (AOR 4.1, 95%CI 1.5-11.5; p = 0.009 and caregiver's alcohol use (AOR 5.5, 95%CI 2.8-10.7; p<0.0001 were associated with ≥ 48-hour interruptions by MEMS, while second-line ART (AOR 0.3, 95%CI 0.1-0.99; p = 0.049 and increasing assets (AOR 0.7, 95%CI 0.6-0.9; p = 0.0007 were protective against these interruptions.Adherence success depends on a well-established medication taking routine, including caregiver support and adequate education on medication changes. Caregiver-reported depression and shame may reflect fear of poor outcomes, functioning as motivation for

  17. Vocanic Deformations During Repose Interval Revealed by GPS Measurements, Batur Volcano, Indonesia

    Science.gov (United States)

    Nishimae, K.; Fujii, N.; Kimata, F.; Murase, M.; Suganda, O. K.; Abidin, H. Z.

    2005-12-01

    Batur volcano is located north west of Bali Island in Indonesia.This volcano has two calderas with more than 10 km in diameter. Recent eruptions with lava flow occurred in 1963 and 1974. No effusion of lava has been observed since 1990, although steam explosions occurred August 1994, November 1997 and June 1998.This suggests that magmatic activity of this volcano would keep its high level since 1994.GPS observation network of this volcano has been kept by Institute Technology of Bandung (ITB) and Volcano Survey of Indonesia (VSI).The network was consisted of 10 observation points at the beginning in 1999, and now it becomes 23 observation points. We have made GPS campaign observations about five times from 2003 to 2005. Each campaign observation consisted of a couple of days of measurements for each observation point. In order to keep the quality of data as high as possible, observations have been made at least 12 hours of continuous data for each point. In this report, results of two campaign observations (December 2004 and July 2005) are used for the analysis. The data thus obtained are fitted to the Mogi source (i.e. a point source model) to locate the depth and amount of volume changes for 7 months. Location of the Mogi source was obtained about 4km southeast of the summit of central cone, and 3km depth with deflation volume change of 1.3_~106 m3 for about 7months. For the period from 1999 to 2004, estimated volume change suggests a continuous deflation throughout this period, although the reliability of data was not so high. Continuous deflations might be likely after the last effusive eruption in 1974, would suggest that shallow part of magma beneath the central cone would probably be drained down to further deep, or shrinkage of magma associated with the cooling or solidification. Further data are obviously needed to discriminate the mechanisms of the deformation process during the repose period in this volcano.

  18. Major outputs of the recent multidisciplinary biogeochemical researches undertaken in the Aegean Sea

    Science.gov (United States)

    Lykousis, V.; Chronis, G.; Tselepides, A.; Price, N. B.; Theocharis, A.; Siokou-Frangou, I.; Van Wambeke, F.; Danovaro, R.; Stavrakakis, S.; Duineveld, G.; Georgopoulos, D.; Ignatiades, L.; Souvermezoglou, A.; Voutsinou-Taliadouri, F.

    2002-06-01

    The main outputs of a multidisciplinary and integrated studies are summarised. The results incorporate the latest biogeochemical researches, at basin scale, in the Aegean Sea (including thermohaline circulation studies, SPM dynamics, mass and energy fluxes, acknowledge biochemical processes in the euphotic and the benthic layer and benthic response to downward fluxes). The data were acquired within five (seasonal) research cruises, during 1997-1998. Data analysis and evaluation hence provided important new information on the functional processes of the Aegean ecosystem. In terms of water circulation, no new deep water formation in the Aegean Sea was observed, during 1997-1998, but rather intermediate water, due mainly to the mild winter conditions. All the biochemical parameters of the euphotic zone (nutrients, Particulate Organic Carbon (POC), chlorophyll- a, phytoplankton, primary and bacterial production), although high in the N. Aegean Sea reflect clearly the highly oligotrophic character of the Aegean Sea. In the N. Aegean, microbial food web was the main pathway of carbon, whereas in the S. Aegean, the food web could be classified as multivorous. An important Black Sea Water (BSW) signal was observed in the dissolved phase; this was especially pronounced in the Dissolved Organic Carbon (DOC), Mn and to a lesser degree to Cd, Cu and Ni concentrations. The downward material fluxes are higher in the N. Aegean, relative to the S. Aegean. Substantially higher values of near-bottom mass fluxes were measured in the deep basins of the N. Aegean, implying significant deep lateral fluxes of POM. The N. Aegean could be classified as a "continental margin" ecosystem, whilst the S. Aegean is a typical "oceanic margin" environment. There is a close relationship and, consequently, coupling between the near-bottom mass fluxes and the accumulation rates of organic matter (OM), with the near-bottom mineralisation, bioturbation, redox potential, oxygen consumption rates, the

  19. Ex vivo measures of muscle mitochondrial capacity reveal quantitative limits of oxygen delivery by the circulation during exercise

    DEFF Research Database (Denmark)

    Boushel, Robert; Saltin, Bengt

    2013-01-01

    Muscle mitochondrial respiratory capacity measured ex vivo provides a physiological reference to assess cellular oxidative capacity as a component in the oxygen cascade in vivo. In this article, the magnitude of muscle blood flow and oxygen uptake during exercise involving a small-to-large fracti...... capacity measured ex vivo underestimates the maximal in vivo oxygen uptake of muscle by up to ∼2-fold. This article is part of a Directed Issue entitled: Bioenergetic dysfunction, adaptation and therapy.......Muscle mitochondrial respiratory capacity measured ex vivo provides a physiological reference to assess cellular oxidative capacity as a component in the oxygen cascade in vivo. In this article, the magnitude of muscle blood flow and oxygen uptake during exercise involving a small-to-large fraction...... of the body mass will be discussed in relation to mitochondrial capacity measured ex vivo. These analyses reveal that as the mass of muscle engaged in exercise increases from one-leg knee extension, to 2-arm cranking, to 2-leg cycling and x-country skiing, the magnitude of blood flow and oxygen delivery...

  20. In-Plane Electronic Anisotropy of Underdoped ___122___ Fe-Arsenide Superconductors Revealed by Measurements of Detwinned Single Crystals

    Energy Technology Data Exchange (ETDEWEB)

    Fisher, Ian Randal

    2012-05-08

    The parent phases of the Fe-arsenide superconductors harbor an antiferromagnetic ground state. Significantly, the Neel transition is either preceded or accompanied by a structural transition that breaks the four fold symmetry of the high-temperature lattice. Borrowing language from the field of soft condensed matter physics, this broken discrete rotational symmetry is widely referred to as an Ising nematic phase transition. Understanding the origin of this effect is a key component of a complete theoretical description of the occurrence of superconductivity in this family of compounds, motivating both theoretical and experimental investigation of the nematic transition and the associated in-plane anisotropy. Here we review recent experimental progress in determining the intrinsic in-plane electronic anisotropy as revealed by resistivity, reflectivity and ARPES measurements of detwinned single crystals of underdoped Fe arsenide superconductors in the '122' family of compounds.

  1. Revealing the hidden faults in the SE flank of Mt. Etna using radon in-soil gas measurement.

    Science.gov (United States)

    Johnová, K; Thinová, L; Giammanco, S

    2014-07-01

    Although there are many methods for investigating tectonic structures, many faults remain hidden, and they can endanger the life and property of people living along them. The slopes of volcanoes are covered with such hidden faults, near which strong earthquakes and gas releases can appear. Revealing hidden faults can therefore contribute significantly to the protection of people living in volcanic areas. In the study, seven different techniques were used for making measurements of in-soil radon concentrations in order to search for hidden faults on the SE flank of the Mt. Etna volcano. These reported methods had previously been proved to be useful tools for investigating fault structures. The main aim of the experiment presented here was to evaluate the usability of these methods in the geological conditions of the Mt. Etna region, and to find the best place for continual radon monitoring using a permanent station in the near future. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  2. Mathematics revealed

    CERN Document Server

    Berman, Elizabeth

    1979-01-01

    Mathematics Revealed focuses on the principles, processes, operations, and exercises in mathematics.The book first offers information on whole numbers, fractions, and decimals and percents. Discussions focus on measuring length, percent, decimals, numbers as products, addition and subtraction of fractions, mixed numbers and ratios, division of fractions, addition, subtraction, multiplication, and division. The text then examines positive and negative numbers and powers and computation. Topics include division and averages, multiplication, ratios, and measurements, scientific notation and estim

  3. The effect of creatinine on the prognosis of patients with acute myocardial infarction undertaken emergency-PCI

    International Nuclear Information System (INIS)

    Chen Hui; Jia Sanqing; Yan Songbiao; Wang Lei; Li Hongwei; Su Shuhong; Gao Hongli; Wang Lu; Han Wei; Shen Luhua

    2006-01-01

    Objective: To observe the effect of creatinine (Cr) on the short and long term prognosis of patients with acute myocardial infarction undertaken emergent-PCI. Methods: A total of 351 consecutive acute myocardial infarction patients from Apr 2000 to Jan 2004 who undertaken emergency-PCI were divided into two groups according to the Cr value: group 1(n=327, Cr<133 μmol/L) and group 2(n=24, Cr≥133 μmol/L); with average age of (63±11) years, average in-hospital days (15.3±8.1) days, and average follow-up period (27.2±13.3) months (6-51 months); for analyzing the effect of Cr on short-term and long-term prognosis. Results: After comparing with those of group 1, the age was higher (P<0.01) in group 2, the levels of total cholesterol (TC, P<0.05) and low density lipoprotein (LDL, P<0.05) were lower in group 2, the levels of C-reactive protein (CRP, P<0.05), Killip classification (P<0.01) and diseased vessel numbers (P<0.05)were higher in group 2. The correlative analysis showed that Cr was significantly linked with these following factors: sex(correlation coefficient -0.16, P<0.01), age(correlation coefficient 0.203, P<0.001), TC ( correlation coefficient-0.134, P<0.05), LDL (correlation coefficient -0.12, P<0.05), hs-CRP (correlation coefficient 0.246, P<0.01), Killip (correlation coefficient 0.142, P<0.01), diseased vessel numbers (correlation coefficient 0.137, P<0.05). Conclusions: The level of Cr is significantly correlated with TC, LDL, CRP, Killip and diseased vessel numbers. It is a very good index to reflect heart function and diseased vessel numbers, but it appears to be not related to the short-term and long-term prognosis. (authors)

  4. REVEALED COMPARATIVE ADVANTAGE AND THE MEASUREMENT OF INTERNATIONAL COMPETITIVENESS FOR AGRICULTURAL COMMODITIES: AN EMPIRICAL ANALYSIS OF WOOL EXPORTERS

    OpenAIRE

    Leishman, David; Menkhaus, Dale J.; Whipple, Glen D.

    1999-01-01

    Trade liberalization and laissez-faire economics are altering the structure of agricultural production and trade. The principle of comparative advantage, a classic tenet of economics, is a useful tool for understanding the future of world agriculture. This study employs a "Revealed Comparative Advantage" approach to investigate patterns of comparative advantage among six major wool exporting countries.

  5. Ecosystem studies in the Indian Ocean sector of the Southern Ocean undertaken by the training vessel Umitaka-maru

    Science.gov (United States)

    Moteki, Masato; Odate, Tsuneo; Hosie, Graham W.; Takahashi, Kunio T.; Swadling, Kerrie M.; Tanimura, Atsushi

    2017-06-01

    This special issue provides an overview of the ten voyages undertaken by the Umitaka-maru from the austral summers of 2002/2003 to 2014/2015 to promote the next phase of study of the ecosystems in the Indian Ocean sector of the Southern Ocean. The voyages by the Umitaka-maru have mainly targeted three areas in the Indian Ocean sector: off Dumont d'Urville Base (France, 140°E transect), off Casey Station (Australia, 110°E transect), and off Syowa Station (Japan, north of Lützow Holm Bay). The findings of Umitaka-maru's research on the krill-independent food web, animal assemblages, community structure and distribution patterns from the epipelagic to the deeper waters provide invaluable information for elucidating the material cycle and predicting future ecosystem changes. Further studies on assessing the influence of sea ice on food webs in the water column are required, which will provide crucial information for predicting ecosystem changes as a result of projected sea ice changes in the near future.

  6. Secondary data analyses of dietary surveys undertaken in South Africa to determine usual food consumption of the population.

    Science.gov (United States)

    Steyn, Nelia Patricia; Nel, Johanna Helena; Casey, Annette

    2003-10-01

    The primary objective of this study was to generate a reference table of food items and average amounts of these items consumed by South Africans, for the Department of Health. The reference table was required to be representative of foods and beverages eaten frequently by children and adults from all age and ethnic groups in order for the Department of Health to test for contaminants in these foods. The National Food Consumption Survey (NFCS) served as a framework for compiling data on children since this was a national representative survey of 1-9-year-old children undertaken in South Africa in 1999. However, there has never been a national dietary survey on adults in South Africa. Consequently the data had to be extrapolated from existing isolated surveys on adults. Secondary data analysis was conducted on existing dietary databases (raw data) obtained from surveys undertaken on adults in South Africa between 1983 and 2000. Available datasets were regional and independent, and were not individually representative of the South African diet. It was therefore necessary to use different statistical methods, including factor analyses, weighting and correlations, to generate ethnic and geographic representative data for adults. Two methods were used: Method 1, which corresponded with results of the NFCS (over-sampled for low socio-economic status), and Method 2, which was based on ethnic proportions of the population. The secondary data analyses generated food items most commonly consumed by the South African adult population (Method 1) in descending frequency of usage and average (mean) amount per day: maize porridge (78%/848 g), white sugar (77%/27 g), tea (68%/456 g), brown bread (55%/165 g), white bread (28%/163 g), non-dairy creamer (25%/6 g), brick margarine (21%/19 g), chicken meat (19%/111 g), full-cream milk (19%/204 g) and green leaves (17%/182 g). In 6-9-year-olds, maize porridge (72%/426 g), sugar (76%/23 g), tea (51%/258 g), full-cream milk (35%/171 g

  7. A comparison of nursing tasks undertaken by regulated nurses and nursing support workers: a work sampling study.

    Science.gov (United States)

    Roche, Michael A; Friedman, Sarah; Duffield, Christine; Twigg, Diane E; Cook, Rebecca

    2017-06-01

    The aim of this study was to determine which tasks unregulated nursing support staff spend their work time undertaking and to determine differences between the work undertaken by licensed/regulated nurses on units which have nursing support workers and those on units which do not. Acute hospital nursing teams often include nursing support staff; little is known about what kinds of tasks these unregulated support workers do and how it affects the work tasks of their licensed/regulated team members. Cross-sectional analysis of nurse work sampling data. Data collection took place between March-October 2013. The proportion of time spent on 25 work activities by nursing support staff and licensed/regulated nursing staff was compared. Logistic regression models estimated whether nursing support staff or licensed/regulated nurses were more likely to conduct direct and indirect patient care tasks and whether licensed/regulated nurses on units with nursing support staff were more likely to conduct direct or indirect tasks compared with those on units without nursing support workers. Nursing support staff spent the majority of their time engaged in direct care tasks, e.g. admission and assessment, hygiene and mobility. Although licensed/regulated nurses were less likely to undertake direct care tasks compared with support workers, those who worked on units with support workers undertook more direct care compared with those who worked on units without support workers. Nursing support workers were given tasks that required substantial amounts of patient interaction. These staff may be associated with an increase in direct care tasks for licensed/regulated nurses, who may duplicate the direct care done by nursing support workers. © 2016 John Wiley & Sons Ltd.

  8. Electronic anisotropies revealed by detwinned angle-resolved photo-emission spectroscopy measurements of FeSe

    Science.gov (United States)

    Watson, Matthew D.; Haghighirad, Amir A.; Rhodes, Luke C.; Hoesch, Moritz; Kim, Timur K.

    2017-10-01

    We report high resolution angle-resolved photo-emission spectroscopy (ARPES) measurements of detwinned FeSe single crystals. The application of a mechanical strain is used to promote the volume fraction of one of the orthorhombic domains in the sample, which we estimate to be 80 % detwinned. While the full structure of the electron pockets consisting of two crossed ellipses may be observed in the tetragonal phase at temperatures above 90 K, we find that remarkably, only one peanut-shaped electron pocket oriented along the longer a axis contributes to the ARPES measurement at low temperatures in the nematic phase, with the expected pocket along b being not observed. Thus the low temperature Fermi surface of FeSe as experimentally determined by ARPES consists of one elliptical hole pocket and one orthogonally-oriented peanut-shaped electron pocket. Our measurements clarify the long-standing controversies over the interpretation of ARPES measurements of FeSe.

  9. Whole-brain analytic measures of network communication reveal increased structure-function correlation in right temporal lobe epilepsy

    Directory of Open Access Journals (Sweden)

    Jonathan Wirsich

    2016-01-01

    In rTLE patients, we found a widespread hypercorrelated functional network. Network communication analysis revealed greater unspecific branching of the shortest path (search information in the structural connectome and a higher global correlation between the structural and functional connectivity for the patient group. We also found evidence for a preserved structural rich-club in the patient group. In sum, global augmentation of structure-function correlation might be linked to a smaller functional repertoire in rTLE patients, while sparing the central core of the brain which may represent a pathway that facilitates the spread of seizures.

  10. The mind-set of teens towards food communications revealed by conjoint measurement and multi-food databases.

    Science.gov (United States)

    Foley, Michele; Beckley, Jacqueline; Ashman, Hollis; Moskowitz, Howard R

    2009-06-01

    We introduce a new type of study that combines self-profile of behaviors and attitudes regarding food together with responses to structured, systematically varied concepts about the food. We deal here with the responses of teens, for 28 different foods and beverages. The study creates a database that reveals how a person responds to different types of messaging about the food. We show how to develop the database for many different foods, from which one can compare foods to each other, or compare the performance of messages within a specific food.

  11. Detailed characteristics of radiation belt electrons revealed by CSSWE/REPTile measurements: Geomagnetic activity response and precipitation observation

    Science.gov (United States)

    Zhang, K.; Li, X.; Schiller, Q.; Gerhardt, D.; Zhao, H.; Millan, R.

    2017-08-01

    Earth's outer radiation belt electrons are highly dynamic. We study the detailed characteristics of relativistic electrons in the outer belt using measurements from the Colorado Student Space Weather Experiment (CSSWE) mission, a low Earth orbit (LEO) CubeSat, which traverses the radiation belt four times in one orbit ( 1.5 h) and has the advantage of measuring the dynamic activities of the electrons including their rapid precipitation. We focus on the measured electron response to geomagnetic activity for different energies to show that there are abundant sub-MeV electrons in the inner belt and slot region. These electrons are further enhanced during active times, while there is a lack of >1.63 MeV electrons in these regions. We also show that the variation of measured electron flux at LEO is strongly dependent on the local magnetic field strength, which is far from a dipole approximation. Moreover, a specific precipitation band, which happened on 19 January 2013, is investigated based on the conjunctive measurement of CSSWE, the Balloon Array for Radiation belt Relativistic Electron Losses, and one of the Polar Operational Environmental Satellites. In this precipitation band event, the net loss of the 0.58-1.63 MeV electrons (L = 3.5-6) is estimated to account for 6.8% of the total electron content.

  12. Single molecule activity measurements of cytochrome P450 oxidoreductase reveal the existence of two discrete functional states

    DEFF Research Database (Denmark)

    Laursen, Tomas; Singha, Aparajita; Rantzau, Nicolai

    2014-01-01

    450 enzymes. Measurements and statistical analy-sis of individual catalytic turnover cycles shows POR to sample at least two major functional states. This phenotype may underlie regulatory interactions with different cytochromes P450 but to date remained masked in bulk kinetics. To ensure that we...

  13. Objective measurement of function following lumbar spinal stenosis decompression reveals improved functional capacity with stagnant real-life physical activity.

    Science.gov (United States)

    Smuck, Matthew; Muaremi, Amir; Zheng, Patricia; Norden, Justin; Sinha, Aman; Hu, Richard; Tomkins-Lane, Christy

    2018-01-01

    Lumbar spinal stenosis (LSS) is a prevalent and costly condition associated with significant dysfunction. Alleviation of pain and improvement of function are the primary goals of surgical intervention. Although prior studies have measured subjective improvements in function after surgery, few have examined objective markers of functional improvement. We aimed to objectively measure and quantify changes in physical capacity and physical performance following surgical decompression of LSS. Prospective cohort study. Thirty-eight patients with LSS determined by the treating surgeon's clinical and imaging evaluation, and who were scheduled for surgical treatment, were consecutively recruited at two academic medical facilities, with 28 providing valid data for analysis at baseline and 6 months after surgery. Before surgery and at 6 months after surgery, participants provided 7 days of real-life physical activity (performance) using ActiGraph accelerometers; completed two objective functional capacity measures, the Short Physical Performance Battery and Self-Paced Walking Test; and completed three subjective functional outcome questionnaires, Oswestry Disability Index, Spinal Stenosis Symptom Questionnaire, and Short-Form 36. Physical activity, as measured by continuous activity monitoring, was analyzed as previously described according to the 2008 American Physical Activity Guidelines. Paired t tests were performed to assess for postsurgical changes in all questionnaire outcomes and all objective functional capacity measures. Chi-square analysis was used to categorically assess whether patients were more likely to meet these physical activity recommendations after surgery. Participants were 70.1 years old (±8.9) with 17 females (60.7%) and an average body mass index of 28.4 (±6.2). All subjective measures (Oswestry Disability Index, Spinal Stenosis Symptom Questionnaire, and Short-Form 36) improved significantly at 6 months after surgery, as did objective functional

  14. Back-Arc Opening in the Western End of the Okinawa Trough Revealed From GNSS/Acoustic Measurements

    Science.gov (United States)

    Chen, Horng-Yue; Ikuta, Ryoya; Lin, Cheng-Horng; Hsu, Ya-Ju; Kohmi, Takeru; Wang, Chau-Chang; Yu, Shui-Beih; Tu, Yoko; Tsujii, Toshiaki; Ando, Masataka

    2018-01-01

    We measured seafloor movement using a Global Navigation Satellite Systems (GNSS)/Acoustic technique at the south of the rifting valley in the western end of the Okinawa Trough back-arc basin, 60 km east of northeastern corner of Taiwan. The horizontal position of the seafloor benchmark, measured eight times between July 2012 and May 2016, showed a southeastward movement suggesting a back-arc opening of the Okinawa Trough. The average velocity of the seafloor benchmark shows a block motion together with Yonaguni Island. The westernmost part of the Ryukyu Arc rotates clockwise and is pulled apart from the Taiwan Island, which should cause the expansion of the Yilan Plain, Taiwan. Comparing the motion of the seafloor benchmark with adjacent seismicity, we suggest a gentle episodic opening of the rifting valley accompanying a moderate seismic activation, which differs from the case in the segment north off-Yonaguni Island where a rapid dyke intrusion occurs with a significant seismic activity.

  15. Edge detection applied to Cassini images reveals no measurable displacement of Ontario Lacus' margin between 2005 and 2010

    Science.gov (United States)

    Cornet, Thomas; Bourgeois, Olivier; Le Mouélic, Stéphane; Rodriguez, Sébastien; Sotin, Christophe; Barnes, Jason W.; Brown, Robert H.; Baines, Kevin H.; Buratti, Bonnie J.; Clark, Roger N.; Nicholson, Phillip D.

    2012-07-01

    Ontario Lacus is thus far the largest flat-floored topographic depression of Titan's southern hemisphere interpreted as a permanent or ephemeral lake. From 2005 to 2010, it was imaged several times and at various wavelengths by ISS, VIMS and RADAR instruments onboard Cassini's spacecraft. We analyze the position and uncertainty of Ontario Lacus' margin in all these images using an edge detection method based on image derivation. We find that, given the range of uncertainties in contour locations derived from images, no measurable displacement of Ontario Lacus' margin can be detected between 2005 and 2010 at the actual image spatial resolutions. The discrepancy between this result and previous ones is attributable to differences in (1) the basics behind the methods used, (2) the actual spatial resolutions and contrasts of the available images due to differential atmospheric scattering effects at different wavelengths, and (3) the geomorphological interpretation of contours derived from images acquired at different wavelengths. This lack of measurable displacement in the images suggests that the imaged contour corresponds either (1) to the border of a surface liquid body, provided that potential changes in its extent over five terrestrial years were not sufficiently large to be measured, or (2) to the stationary topographic border between Ontario Lacus' depression and the surrounding alluvial plain. Potential displacements of Ontario Lacus' margin between 2005 and 2010 are thus below the actual resolution of currently available images or have to be sought for within the extent of the topographic depression rather than along its borders.

  16. Satellite chlorophyll fluorescence measurements reveal large-scale decoupling of photosynthesis and greenness dynamics in boreal evergreen forests.

    Science.gov (United States)

    Walther, Sophia; Voigt, Maximilian; Thum, Tea; Gonsamo, Alemu; Zhang, Yongguang; Köhler, Philipp; Jung, Martin; Varlagin, Andrej; Guanter, Luis

    2016-09-01

    Mid-to-high latitude forests play an important role in the terrestrial carbon cycle, but the representation of photosynthesis in boreal forests by current modelling and observational methods is still challenging. In particular, the applicability of existing satellite-based proxies of greenness to indicate photosynthetic activity is hindered by small annual changes in green biomass of the often evergreen tree population and by the confounding effects of background materials such as snow. As an alternative, satellite measurements of sun-induced chlorophyll fluorescence (SIF) can be used as a direct proxy of photosynthetic activity. In this study, the start and end of the photosynthetically active season of the main boreal forests are analysed using spaceborne SIF measurements retrieved from the GOME-2 instrument and compared to that of green biomass, proxied by vegetation indices including the Enhanced Vegetation Index (EVI) derived from MODIS data. We find that photosynthesis and greenness show a similar seasonality in deciduous forests. In high-latitude evergreen needleleaf forests, however, the length of the photosynthetically active period indicated by SIF is up to 6 weeks longer than the green biomass changing period proxied by EVI, with SIF showing a start-of-season of approximately 1 month earlier than EVI. On average, the photosynthetic spring recovery as signalled by SIF occurs as soon as air temperatures exceed the freezing point (2-3 °C) and when the snow on the ground has not yet completely melted. These findings are supported by model data of gross primary production and a number of other studies which evaluated in situ observations of CO2 fluxes, meteorology and the physiological state of the needles. Our results demonstrate the sensitivity of space-based SIF measurements to light-use efficiency of boreal forests and their potential for an unbiased detection of photosynthetic activity even under the challenging conditions interposed by evergreen

  17. Whole-brain analytic measures of network communication reveal increased structure-function correlation in right temporal lobe epilepsy.

    Science.gov (United States)

    Wirsich, Jonathan; Perry, Alistair; Ridley, Ben; Proix, Timothée; Golos, Mathieu; Bénar, Christian; Ranjeva, Jean-Philippe; Bartolomei, Fabrice; Breakspear, Michael; Jirsa, Viktor; Guye, Maxime

    2016-01-01

    The in vivo structure-function relationship is key to understanding brain network reorganization due to pathologies. This relationship is likely to be particularly complex in brain network diseases such as temporal lobe epilepsy, in which disturbed large-scale systems are involved in both transient electrical events and long-lasting functional and structural impairments. Herein, we estimated this relationship by analyzing the correlation between structural connectivity and functional connectivity in terms of analytical network communication parameters. As such, we targeted the gradual topological structure-function reorganization caused by the pathology not only at the whole brain scale but also both in core and peripheral regions of the brain. We acquired diffusion (dMRI) and resting-state fMRI (rsfMRI) data in seven right-lateralized TLE (rTLE) patients and fourteen healthy controls and analyzed the structure-function relationship by using analytical network communication metrics derived from the structural connectome. In rTLE patients, we found a widespread hypercorrelated functional network. Network communication analysis revealed greater unspecific branching of the shortest path (search information) in the structural connectome and a higher global correlation between the structural and functional connectivity for the patient group. We also found evidence for a preserved structural rich-club in the patient group. In sum, global augmentation of structure-function correlation might be linked to a smaller functional repertoire in rTLE patients, while sparing the central core of the brain which may represent a pathway that facilitates the spread of seizures.

  18. Results of a paleomagnetic survey undertaken in the Damara mobile belt, South West Africa, with special reference to the magnetisation of the uraniferous pegmatitic granites

    International Nuclear Information System (INIS)

    Corner, B.; Henthorn, D.I.

    1978-10-01

    A project study, undertaken by the Geology Division of the AEB, on the correlation between airborne magnetic and radiometric data covering a portion of the Damara Mobile Belt in South West Africa, has revealed that all the known occurrences of uranium in late- to post-tectonic leucogranite (alaskite) of the Damara orogeny are associated with negative geomagnetic anomalies. Although the uranium occurrences themselves do not display marked geomagnetic anomalies, their immediate geological environment is characterised by the negative anomalies, which are semi-regional in extent. To investigate the origin of these anomalies, the Atomic Energy Board and the Geological Survey of South Africa undertook a palaeomagnetic study of the area. Oriented cores were taken from 31 sites in the mobile belt, 18 of which were selected within the negative magnetic zones, mostly in close association with known uraniferous alaskitic granites. Palaeomagnetic evidence suggests that the negative geomagnetic anomalies are associated with a remanent magnetisation, resulting from the Damara orogenic event, whose direction is removed from the earth's present field and which has affected rocks of the Nosib Group. Absence of this stable remanent direction in rocks stratigraphically overlying the Nosib Group accounts for the distinctive geomagnetic signature, in the form of negative anomalies, of the Nosib Group. It is this signature which can be used in airborne surveys to identify rocks of the Nosib Group outcropping, or of shallow suboutcrop, in anticlinal or dome-like structures. Since the uraniferous alaskites are mostly confined stratigraphically to the Nosib Group, the negative geomagnetic anomalies form an important prospecting criterion as they may be used to delineate target areas for further exploration in areas covered by sand, scree and duricrust deposits [af

  19. Satellite-based measurements of surface deformation reveal fluid flow associated with the geological storage of carbon dioxide

    Energy Technology Data Exchange (ETDEWEB)

    Vasco, D.W.; Rucci, A.; Ferretti, A.; Novali, F.; Bissell, R.; Ringrose, P.; Mathieson, A.; Wright, I.

    2009-10-15

    Interferometric Synthetic Aperture Radar (InSAR), gathered over the In Salah CO{sub 2} storage project in Algeria, provides an early indication that satellite-based geodetic methods can be effective in monitoring the geological storage of carbon dioxide. An injected volume of 3 million tons of carbon dioxide, from one of the first large-scale carbon sequestration efforts, produces a measurable surface displacement of approximately 5 mm/year. Using geophysical inverse techniques we are able to infer flow within the reservoir layer and within a seismically detected fracture/ fault zone intersecting the reservoir. We find that, if we use the best available elastic Earth model, the fluid flow need only occur in the vicinity of the reservoir layer. However, flow associated with the injection of the carbon dioxide does appear to extend several kilometers laterally within the reservoir, following the fracture/fault zone.

  20. Thermoelastic properties of liquid Fe-C revealed by sound velocity and density measurements at high pressure

    Science.gov (United States)

    Shimoyama, Yuta; Terasaki, Hidenori; Urakawa, Satoru; Takubo, Yusaku; Kuwabara, Soma; Kishimoto, Shunpachi; Watanuki, Tetsu; Machida, Akihiko; Katayama, Yoshinori; Kondo, Tadashi

    2016-11-01

    Carbon is one of the possible light elements in the cores of the terrestrial planets. The P wave velocity (VP) and density (ρ) are important factors for estimating the chemical composition and physical properties of the core. We simultaneously measured the VP and ρ of Fe-3.5 wt % C up to 3.4 GPa and 1850 K by using ultrasonic pulse-echo method and X-ray absorption methods. The VP of liquid Fe-3.5 wt % C decreased linearly with increasing temperature at constant pressure. The addition of carbon decreased the VP of liquid Fe by about 2% at 3 GPa and 1700 K and decreased the Fe density by about 2% at 2 GPa and 1700 K. The bulk modulus of liquid Fe-C and its pressure (P) and temperature (T) effects were precisely determined from directly measured ρ and VP data to be K0,1700 K = 83.9 GPa, dKT/dP = 5.9(2), and dKT/dT = -0.063 GPa/K. The addition of carbon did not affect the isothermal bulk modulus (KT) of liquid Fe, but it decreased the dK/dT of liquid Fe. In the ρ-VP relationship, VP increases linearly with ρ and can be approximated as VP (m/s) = -6786(506) + 1537(71) × ρ (g/cm3), suggesting that Birch's law is valid for liquid Fe-C at the present P-T conditions. Our results imply that at the conditions of the lunar core, the elastic properties of an Fe-C core are more affected by temperature than those of Fe-S core.

  1. High resolution LiDAR measurements reveal fine internal structure and variability of sediment-carrying coastal plume

    Science.gov (United States)

    Zavialov, P. O.; Pelevin, V. V.; Belyaev, N. A.; Izhitskiy, A. S.; Konovalov, B. V.; Krementskiy, V. V.; Goncharenko, I. V.; Osadchiev, A. A.; Soloviev, D. M.; Garcia, C. A. E.; Pereira, E. S.; Sartorato, L.; Moller, O. O.

    2018-05-01

    We report results of a field survey conducted in the buoyant, sediment-carrying coastal plume generated by the discharge from the Patos Lagoon, the World's largest choked lagoon. The concentration of total suspended matter (TSM) and organic matter (as represented by total organic carbon, TOC) were mapped using an ultraviolet fluorescent LiDAR, which allowed for extensive data coverage (total of 79,387 simultaneous determinations of TSM and TOC) during 3 consecutive days. These observations were accompanied by hydrographic measurements from the ship and at a mooring station. We first describe synoptic variability of the plume, which responded energetically to wind forcing. We then analyze the TSM, TOC and hydrographic data jointly and develop a simple approach to estimate the rates of suspended matter removal from the upper layer due to gravitational settling and turbulent mixing based on relative changes in TSM and TOC concentrations. Four distinct regions within the plume exhibiting different dynamics of suspended and dissolved constituents were identified on this basis.

  2. Simple measurements reveal the feeding history, the onset of reproduction, and energy conversion efficiencies in captive bluefin tuna

    Science.gov (United States)

    Jusup, Marko; Klanjšček, Tin; Matsuda, Hiroyuki

    2014-11-01

    We present a numerical approach that, in conjunction with a fully set up Dynamic Energy Budget (DEB) model, aims at consistently approximating the feeding history of cultivated fish from the commonly measured aquaculture data (body length, body mass, or the condition factor). We demonstrate the usefulness of the approach by performing validation of a DEB-based model for Pacific bluefin tuna (Thunnus orientalis) on an independent dataset and exploring the implied bioenergetics of this species in captivity. In the context of validation, the results indicate that the model successfully accounts for more than 75% of the variance in actual fish feed. At the 5% significance level, predictions do not underestimate nor overestimate observations and there is no bias. The overall model accuracy of 87.6% is satisfactory. In the context of tuna bioenergetics, we offer an explanation as to why the first reproduction in the examined case occurred only after the fish reached seven years of age, whereas it takes five years in the wild and sometimes as little as three years in captivity. Finally, we calculate energy conversion efficiencies and the supply stress throughout the entire lifetime to theoretically underpin the relatively low contribution of growth to aerobic metabolism implied by respirometry and high feed conversion ratio observed in bluefin tuna aquaculture.

  3. Tidal and flood signatures of settling particles in the Gaoping submarine canyon (SW Taiwan) revealed from radionuclide and flow measurements

    Science.gov (United States)

    Huh, C.-A.; Liu, J.T.; Lin, H.-L.; Xu, J. P.

    2009-01-01

    Sediment transport and sedimentation processes in the Gaoping submarine canyon were studied using sediment trap and current meter moorings deployed at a location during the winter (January-March) and the summer (July-September) months in 2008. At the end of each deployment, sediment cores were also collected from the canyon floor at the mooring site. Samples from sediment traps and sediment cores were analyzed for 210Pb and 234Th by gamma spectrometry. In conjunction with particle size and flow measurements, the datasets suggest that sediment transport in the canyon is tidally-modulated in the drier winter season and flood (river)-dominated in the wetter summer season. From the magnitude and temporal variation of sediment flux in the canyon with respect to the burial flux and sediment budget on the open shelf and slope region, we reaffirm that, on annual or longer timescales, the Gaoping submarine canyon is an effective conduit transporting sediments from the Gaoping River's drainage basin (the source) to the deep South China Sea (the ultimate sink). ?? 2009 Elsevier B.V.

  4. Redefining "Learning" in Statistical Learning: What Does an Online Measure Reveal About the Assimilation of Visual Regularities?

    Science.gov (United States)

    Siegelman, Noam; Bogaerts, Louisa; Kronenfeld, Ofer; Frost, Ram

    2017-10-07

    From a theoretical perspective, most discussions of statistical learning (SL) have focused on the possible "statistical" properties that are the object of learning. Much less attention has been given to defining what "learning" is in the context of "statistical learning." One major difficulty is that SL research has been monitoring participants' performance in laboratory settings with a strikingly narrow set of tasks, where learning is typically assessed offline, through a set of two-alternative-forced-choice questions, which follow a brief visual or auditory familiarization stream. Is that all there is to characterizing SL abilities? Here we adopt a novel perspective for investigating the processing of regularities in the visual modality. By tracking online performance in a self-paced SL paradigm, we focus on the trajectory of learning. In a set of three experiments we show that this paradigm provides a reliable and valid signature of SL performance, and it offers important insights for understanding how statistical regularities are perceived and assimilated in the visual modality. This demonstrates the promise of integrating different operational measures to our theory of SL. © 2017 Cognitive Science Society, Inc.

  5. Continuous gravity measurements reveal a low-density lava lake at Kīlauea Volcano, Hawai‘i

    Science.gov (United States)

    Carbone, Daniele; Poland, Michael P.; Patrick, Matthew R.; Orr, Tim R.

    2013-01-01

    On 5 March 2011, the lava lake within the summit eruptive vent at Kīlauea Volcano, Hawai‘i, began to drain as magma withdrew to feed a dike intrusion and fissure eruption on the volcanoʼs east rift zone. The draining was monitored by a variety of continuous geological and geophysical measurements, including deformation, thermal and visual imagery, and gravity. Over the first ∼14 hours of the draining, the ground near the eruptive vent subsided by about 0.15 m, gravity dropped by more than 100 μGal, and the lava lake retreated by over 120 m. We used GPS data to correct the gravity signal for the effects of subsurface mass loss and vertical deformation in order to isolate the change in gravity due to draining of the lava lake alone. Using a model of the eruptive vent geometry based on visual observations and the lava level over time determined from thermal camera data, we calculated the best-fit lava density to the observed gravity decrease — to our knowledge, the first geophysical determination of the density of a lava lake anywhere in the world. Our result, 950 +/- 300 kg m-3, suggests a lava density less than that of water and indicates that Kīlaueaʼs lava lake is gas-rich, which can explain why rockfalls that impact the lake trigger small explosions. Knowledge of such a fundamental material property as density is also critical to investigations of lava-lake convection and degassing and can inform calculations of pressure change in the subsurface magma plumbing system.

  6. Functional diversity measures revealed impacts of non-native species and habitat degradation on species-poor freshwater fish assemblages.

    Science.gov (United States)

    Colin, Nicole; Villéger, Sébastien; Wilkes, Martin; de Sostoa, Adolfo; Maceda-Veiga, Alberto

    2018-06-01

    Trait-based ecology has been developed for decades to infer ecosystem responses to stressors based on the functional structure of communities, yet its value in species-poor systems is largely unknown. Here, we used an extensive dataset in a Spanish region highly prone to non-native fish invasions (15 catchments, N=389 sites) to assess for the first time how species-poor communities respond to large-scale environmental gradients using a taxonomic and functional trait-based approach in riverine fish. We examined total species richness and three functional trait-based indices available when many sites have ≤3 species (specialization, FSpe; originality, FOri and entropy, FEnt). We assessed the responses of these taxonomic and functional indices along gradients of altitude, water pollution, physical habitat degradation and non-native fish biomass. Whilst species richness was relatively sensitive to spatial effects, functional diversity indices were responsive across natural and anthropogenic gradients. All four diversity measures declined with altitude but this decline was modulated by physical habitat degradation (richness, FSpe and FEnt) and the non-native:total fish biomass ratio (FSpe and FOri) in ways that varied between indices. Furthermore, FSpe and FOri were significantly correlated with Total Nitrogen. Non-native fish were a major component of the taxonomic and functional structure of fish communities, raising concerns about potential misdiagnosis between invaded and environmentally-degraded river reaches. Such misdiagnosis was evident in a regional fish index widely used in official monitoring programs. We recommend the application of FSpe and FOri to extensive datasets from monitoring programs in order to generate valuable cross-system information about the impacts of non-native species and habitat degradation, even in species-poor systems. Scoring non-native species apart from habitat degradation in the indices used to determine ecosystem health is

  7. Distinct degassing processes during lava fountains revealed by OP-FTIR measurements: Mt. Etna's 2001 lava fountain sequence

    Science.gov (United States)

    La Spina, Alessandro; Burton, Mike; Allard, Patrick; Alparone, Salvatore; Murè, Filippo

    2010-05-01

    During the two months preceding the 2001 July-August flank eruption of Mt. Etna, 17 discrete lava fountaining events were observed at the southeast crater (SEC, 3250 m a.s.l.). Each episode was preceded by lava effusion and mild strombolian activity from a fracture on the NE flank of the SEC. We used an open-path Fourier transform infrared spectrometer (OP-FTIR) to measure every about 5 seconds an IR absorption spectrum of the gas powering the lava fountains, lava being the source of radiation. Spectral-fitting procedures allowed retrieval of the relative amounts of H2O, CO2, SO2, HCl and HF present in the volcanic gas phase, allowing us to track variations in the gas composition both during each fountain event and over the entire sequence. We present the chemical composition of gases emitted from the SEC during 9 of the 17 lava fountaining events. Three distinct phases in each fountain were observed in terms of seismic tremor, volcanic activity and gas composition. We observed the following: (i) The highest CO2/SO2 ratio observed during each paroxysm coincided with the peak in fountaining intensity and seismic tremor amplitude; (ii) The longer the pause between lava fountains the higher the observed peak CO2/SO2 ratio and tremor amplitude; and (iii) the SO2/HCl ratio noticeably decreased during phases of enhanced fine ash emission. We interpret the variations in gas composition and volcanic activity as due to the combined effects of two distinct processes: periodic emptying of a bubble foam layer accumulating at ~2 km depth and syn-eruptive degassing during magma fragmentation. The clear correlation between the repose time between lava fountains and their intensity and CO2/SO2 peak ratio evidences a main control of the fountain series by bubble foam accumulation and emptying. The surprising decrease in SO2/HCl during the peaks in eruptive activity is attributed to enhanced HCl outgassing during more extensive magma fragmentation and entrainment of atmospheric air

  8. Triplex DNA-binding proteins are associated with clinical outcomes revealed by proteomic measurements in patients with colorectal cancer

    Directory of Open Access Journals (Sweden)

    Nelson Laura D

    2012-06-01

    Full Text Available Abstract Background Tri- and tetra-nucleotide repeats in mammalian genomes can induce formation of alternative non-B DNA structures such as triplexes and guanine (G-quadruplexes. These structures can induce mutagenesis, chromosomal translocations and genomic instability. We wanted to determine if proteins that bind triplex DNA structures are quantitatively or qualitatively different between colorectal tumor and adjacent normal tissue and if this binding activity correlates with patient clinical characteristics. Methods Extracts from 63 human colorectal tumor and adjacent normal tissues were examined by gel shifts (EMSA for triplex DNA-binding proteins, which were correlated with clinicopathological tumor characteristics using the Mann-Whitney U, Spearman’s rho, Kaplan-Meier and Mantel-Cox log-rank tests. Biotinylated triplex DNA and streptavidin agarose affinity binding were used to purify triplex-binding proteins in RKO cells. Western blotting and reverse-phase protein array were used to measure protein expression in tissue extracts. Results Increased triplex DNA-binding activity in tumor extracts correlated significantly with lymphatic disease, metastasis, and reduced overall survival. We identified three multifunctional splicing factors with biotinylated triplex DNA affinity: U2AF65 in cytoplasmic extracts, and PSF and p54nrb in nuclear extracts. Super-shift EMSA with anti-U2AF65 antibodies produced a shifted band of the major EMSA H3 complex, identifying U2AF65 as the protein present in the major EMSA band. U2AF65 expression correlated significantly with EMSA H3 values in all extracts and was higher in extracts from Stage III/IV vs. Stage I/II colon tumors (p = 0.024. EMSA H3 values and U2AF65 expression also correlated significantly with GSK3 beta, beta-catenin, and NF- B p65 expression, whereas p54nrb and PSF expression correlated with c-Myc, cyclin D1, and CDK4. EMSA values and expression of all three splicing factors correlated

  9. Evaluation of Efficiency Activities in the Industrial Sector Undertaken in Response to Greenhouse Gas Emission Reduction Targets

    Energy Technology Data Exchange (ETDEWEB)

    Price, Lynn; de la Rue du Can, Stephane; Lu, Hongyou; Horvath, Arpad

    2010-05-21

    The 2006 California Global Warming Solutions Act calls for reducing greenhouse gas (GHG) emissions to 1990 levels by 2020. Meeting this target will require action from all sectors of the California economy, including industry. The industrial sector consumes 25% of the energy used and emits 28% of the carbon dioxide (CO{sub 2}) produced in the state. Many countries around the world have national-level GHG reduction or energy-efficiency targets, and comprehensive programs focused on implementation of energy efficiency and GHG emissions mitigation measures in the industrial sector are essential for achieving their goals. A combination of targets and industry-focused supporting programs has led to significant investments in energy efficiency as well as reductions in GHG emissions within the industrial sectors in these countries. This project has identified program and policies that have effectively targeted the industrial sector in other countries to achieve real energy and CO{sub 2} savings. Programs in Ireland, France, The Netherlands, Denmark, and the UK were chosen for detailed review. Based on the international experience documented in this report, it is recommended that companies in California's industrial sector be engaged in a program to provide them with support to meet the requirements of AB32, The Global Warming Solution Act. As shown in this review, structured programs that engage industry, require members to evaluate their potential efficiency measures, plan how to meet efficiency or emissions reduction goals, and provide support in achieving the goals, can be quite effective at assisting companies to achieve energy efficiency levels beyond those that can be expected to be achieved autonomously.

  10. Approach undertaken by our Company for leveling electric loads; Chubu Denryoku Kabushi Kaisha no fuka heijunka eno torikumi ni tsuite

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-07-01

    Measures for leveling the electric loads relying upon two facets - tariff system and business activities - in Chubu Electric Power Co., Inc. are presented. Firstly, the existing pricing systems for midnight electric power and electric light according to the period of time for the household as well as those of seasonal and time zone electric power, modifiable contract with the time zone and so forth for large industry users, together with a similar contract for the owner of regenerating installation are outlined. In addition, a price reduction system is indicated in favor of a scheduled shutdown of large industry operations as a means of avoiding electric consumption during weekdays in summer and between 13h and 16h when large demands exist. Further, a selective contract system put in service in 1995 and the price reduction for ice regenerating air conditioning system are cited. As for business facet, 1995 is regarded as the first year of the ice regenerator for its generalization through exhibition and promotive campaign to the foods processing industry, and the application of the latent heat regenerative system to perishable foods is recommended. Moreover, installation of energy saving type automatic vending machine, so-called eco-vendor is encouraged for its merit of peak-cut and energy price lowering. Lastly, activities to extend the use of electric calorifiers and the regenerative floor heating are mentioned. 2 figs., 1 tab.

  11. Why are primary school children overweight and obese? A cross sectional study undertaken in Kinondoni district, Dar-es-salaam.

    Science.gov (United States)

    Mwaikambo, Sijenunu A; Leyna, Germana H; Killewo, Japhet; Simba, Azma; Puoane, Thandi

    2015-12-21

    The world is experiencing an alarming increase in prevalence of childhood obesity. Despite this trend little is known about determinants of childhood obesity in Tanzania. A cross sectional study determined the prevalence and factors associated with overweight and obesity in 1722 children aged 7-14 years (10.9 ± 1.74) attending primary schools in Dar es Salaam. Six public and four private schools were systemically selected from a total of 227 primary schools. Anthropometric measurements (weight and height) were collected using a standard protocol and Body Mass Index (BMI) was calculated. Interviews collected demographic characteristics and lifestyle factors. Multiple logistic regression test was used to assess the influence of independent variables on overweight and obesity while controlling for confounding factors. The level of significance was set at α = 5 %. Of 1, 722 children 10.2 % were overweight and 4.5 % were obese. Overweight and obesity was higher in boys (14.9 %) than girls (14.5 %), higher in children attending private schools (27.7 %) than public schools (5.9 %). Children who walked to and from school were less likely to be overweight or obese than those who used vehicles (AOR = 0.5; 95%CI: 0.3-0.6; p overweight or obese than those who used public transport (AOR = 2.9; 95%CI: 0.2-0.7; p overweight and obesity (AOR = 1.6; 95%CI: 1.1-2.3; p = 0.03). Lunch provided by schools was associated with increased risk of overweight or obese (AOR = 6.4, 95 % CI = 4.2-9.6, p overweight and obesity. Parents and teachers should encourage children to be physically active by limiting screen time and promoting active transport to and from school to promote health and reduce obesity. Ministry of education needs to formulate/enforce policies that encourage physical activities for school children and regulate quality of foods provided to children at schools.

  12. Time-measured phylogenies of gag, pol and env sequence data reveal the direction and time interval of HIV-1 transmission.

    Science.gov (United States)

    Rachinger, Andrea; Groeneveld, Paul H P; van Assen, Sander; Lemey, Philippe; Schuitemaker, Hanneke

    2011-05-15

    To investigate whether time-measured phylogenetic analysis of longitudinal viral sequences can establish the direction and timing of HIV-1 transmission in an epidemiologically linked transmission cluster of three homosexual men. An HIV-1-infected homosexual man (patient 1) and his long-term HIV-negative partner (patient 2) engaged in a triangular relationship with an additional partner (patient 3). On the basis of phylogenetic analysis of gag sequences, patient 3 was previously identified as the source for superinfection of patient 1 but the source of HIV-1 infection of patient 2, who seroconverted during the triangular relationship, remained unclear. Here, we set out to analyze newly obtained gag, pol and env sequences from all three patients to fully elucidate the transmission history in this epidemiologically linked cluster. Bayesian Markov Chain Monte Carlo (MCMC) phylogenetic analyses incorporating a relaxed clock model and a flexible Bayesian skyride tree prior were applied to the longitudinally obtained gag, pol and env sequences from all three patients. Our time-measured evolutionary reconstructions convincingly supported transmission of HIV-1 from the new partner patient 3 to both patients 1 and 2. In addition, estimates of viral divergence times assisted in narrowing down the transmission intervals delineated by seroconversion estimates. Our analysis implies that Bayesian MCMC phylogenetic reconstruction incorporating temporal information can indeed reveal the direction of multiple HIV-1 transmission events in an epidemiologically linked cluster and provide more detail on the timing of transmission.

  13. Image processing techniques revealing the relationship between the field-measured ambient gamma dose equivalent rate and geological conditions at a granitic area, Velence Mountains, Hungary

    Science.gov (United States)

    Beltran Torres, Silvana; Petrik, Attila; Zsuzsanna Szabó, Katalin; Jordan, Gyozo; Szabó, Csaba

    2017-04-01

    In order to estimate the annual dose that the public receive from natural radioactivity, the identification of the potential risk areas is required which, in turn, necessitates understanding the relationship between the spatial distribution of natural radioactivity and the geogenic risk factors (e.g., rock types, dykes, faults, soil conditions, etc.). A detailed spatial analysis of ambient gamma dose equivalent rate was performed in the western side of Velence Mountains, the largest outcropped granitic area in Hungary. In order to assess the role of local geology in the spatial distribution of ambient gamma dose rates, field measurements were carried out at ground level at 300 sites along a 250 m x 250 m regular grid in a total surface of 14.7 km2. Digital image processing methods were applied to identify anomalies, heterogeneities and spatial patterns in the measured gamma dose rates, including local maxima and minima determination, digital cross sections, gradient magnitude and gradient direction, second derivative profile curvature, local variability, lineament density, 2D autocorrelation and directional variogram analyses. Statistical inference showed that different gamma dose rate levels are associated with the rock types (i.e., Carboniferous granite, Pleistocene colluvial, proluvial, deluvial sediments and talus, and Pannonian sand and pebble), with the highest level on the Carboniferous granite including outlying values. Moreover, digital image processing revealed that linear gamma dose rate spatial features are parallel to the SW-NE dyke system and possibly to the NW-SE main fractures. The results of this study underline the importance of understanding the role of geogenic risk factors influencing the ambient gamma dose rate received by public. The study also demonstrates the power of the image processing techniques for the identification of spatial pattern in field-measured geogenic radiation.

  14. In vivo measurements of cerebral metabolic abnormalities by proton spectroscopy after a transient ischemic attack revealing an internal carotid stenosis > 70%

    International Nuclear Information System (INIS)

    Giroud, M.; Becker, F.; Lemesle, M.; Walker, P.; Guy, F.; Martin, D.; Baudouin, N.; Brunotte, F.; Dumas, R.

    1996-01-01

    Aims: The aim of this work is to look for cerebral metabolic abnormalities within the first 3 days after a transient ischemic attack revealing an internal carotid stenosis > 70 %. Methods: Five patients with a transient ischemic attack lasting between 30 and 180 minutes, affecting sensory and motor brachio-facial territory, with or without aphasia. Were studied. A CT-scan, an EEG, a cervical Doppler ultrasound, a standard arteriography, a magnetic resonance imaging and a proton spectroscopy were performed within the cerebral area affected by the transient ischemic attack. We measured 2 markers: N-acetyl-aspartate, the marker of the neuronal mass, and lactate, the marker of anaerobe metabolism. In each case, a contralateral internal stenosis was diagnosed by cervical Doppler ultrasound and standard arteriography. No cerebral infarction was observed. Results: With the affected cerebral area defined according to clinical and EEG features, proton spectroscopy showed a significant rise of lactate, without any change in N-acetyl-aspartate levels. Conclusions: Within the first 3 days after a transient ischemic attack, there is a significant risk of lactate inside the affected cerebral area. This change may reflect a localized and transient hypoperfusion, but long enough to induce a rise of lactate but not sufficient to produce a cerebral infarct. This area is probably at risk to induce cerebral infarct. This data lead us to study the metabolic change induced by the asymptomatic internal carotid stenosis. (authors). 18 refs

  15. Regular in situ measurements of HDO/H216O in the northern and southern hemispherical upper troposphere reveal tropospheric transport processes.

    Science.gov (United States)

    Christner, Emanuel; Dyroff, Christoph; Sanati, Shahrokh; Brenninkmeijer, Carl; Zahn, Andreas

    2013-04-01

    Atmospheric water in form of water vapor and clouds is an enormously crucial trace species. It is responsible for ~70 % of the natural greenhouse effect (Schmidt et al., JGR, 2010), carries huge amounts of latent heat, and is the major source of OH in the troposphere. The isotopic composition of water vapor is an elegant tracer for a better understanding and quantification of the extremely complex and variable hydrological cycle in Earth's atmosphere (evaporation, cloud condensation, rainout, re-evaporation, snow), which in turn is a prerequisite to improve climate modeling and predictions. In this context, water-isotopologues (here the isotope ratio HDO/H216O) can be used to study the atmospheric transport of water and in-cloud processes. As H216O and HDO differ in vapor pressure and molecular diffusion, fractionation occurs during condensation and rainout events. For that reason the ratio HDO/H216O preserves information about the transport and condensation history of an air mass. The tunable diode-laser absorption spectrometer ISOWAT was developed for airborne measurements of the water-isotopologue concentrations of H216O and HDO, probing fundamental rovibrational water-absorption lines at around 2.66 μm. Since April 2010 the spectrometer is regularly operated aboard the CARIBIC passenger aircraft (Civil Aircraft for the Regular Investigation of the atmosphere Based on an Instrument Container - Lufthansa, Airbus 340-600), which measures ~100 trace gases and aerosol components in the UTLS (9-12 km altitude) on four long-distance flights per month. During several flights across the equator (Africa) or close to the equator (Venezuela and Malaysia) an increase of HDO/H216O from the subtropics towards the tropics was measured (by more than 100 permil) at an altitude of ~12 km. This isotopic gradient can partly be attributed to differences in humidity. In addition there is a humidity independent latitudinal gradient (by more than 50 permil), revealing the strong

  16. Measurements of salivary alpha amylase and salivary cortisol in hominoid primates reveal within-species consistency and between-species differences.

    Directory of Open Access Journals (Sweden)

    Verena Behringer

    Full Text Available Salivary alpha amylase (sAA is the most abundant enzyme in saliva. Studies in humans found variation in enzymatic activity of sAA across populations that could be linked to the copy number of loci for salivary amylase (AMY1, which was seen as an adaptive response to the intake of dietary starch. In addition to diet dependent variation, differences in sAA activity have been related to social stress. In a previous study, we found evidence for stress-induced variation in sAA activity in the bonobos, a hominoid primate that is closely related to humans. In this study, we explored patterns of variation in sAA activity in bonobos and three other hominoid primates, chimpanzee, gorilla, and orangutan to (a examine if within-species differences in sAA activity found in bonobos are characteristic for hominoids and (b assess the extent of variation in sAA activity between different species. The results revealed species-differences in sAA activity with gorillas and orangutans having higher basal sAA activity when compared to Pan. To assess the impact of stress, sAA values were related to cortisol levels measured in the same saliva samples. Gorillas and orangutans had low salivary cortisol concentrations and the highest cortisol concentration was found in samples from male bonobos, the group that also showed the highest sAA activity. Considering published information, the differences in sAA activity correspond with differences in AMY1 copy numbers and match with general features of natural diet. Studies on sAA activity have the potential to complement molecular studies and may contribute to research on feeding ecology and nutrition.

  17. Characterizing an Integrated Annual Global Measure of the Earth's Maximum Land Surface Temperatures from 2003 to 2012 Reveals Strong Biogeographic Influences

    Science.gov (United States)

    Mildrexler, D. J.; Zhao, M.; Running, S. W.

    2014-12-01

    Land Surface Temperature (LST) is a good indicator of the surface energy balance because it is determined by interactions and energy fluxes between the atmosphere and the ground. The variability of land surface properties and vegetation densities across the Earth's surface changes these interactions and gives LST a unique biogeographic influence. Natural and human-induced disturbances modify the surface characteristics and alter the expression of LST. This results in a heterogeneous and dynamic thermal environment. Measurements that merge these factors into a single global metric, while maintaining the important biophysical and biogeographical factors of the land surface's thermal environment are needed to better understand integrated temperature changes in the Earth system. Using satellite-based LST we have developed a new global metric that focuses on one critical component of LST that occurs when the relationship between vegetation density and surface temperature is strongly coupled: annual maximum LST (LSTmax). A 10 year evaluation of LSTmax histograms that include every 1-km pixel across the Earth's surface reveals that this integrative measurement is strongly influenced by the biogeographic patterns of the Earth's ecosystems, providing a unique comparative view of the planet every year that can be likened to the Earth's thermal maximum fingerprint. The biogeographical component is controlled by the frequency and distribution of vegetation types across the Earth's land surface and displays a trimodal distribution. The three modes are driven by ice covered polar regions, forests, and hot desert/shrubland environments. In ice covered areas the histograms show that the heat of fusion results in a convergence of surface temperatures around the melting point. The histograms also show low interannual variability reflecting two important global land surface dynamics; 1) only a small fraction of the Earth's surface is disturbed in any given year, and 2) when

  18. A review and rationalisation of journal subscriptions undertaken by a library and information service in a mental health trust in north-east England in 2009.

    Science.gov (United States)

    Steele, Rachel

    2011-12-01

    To describe the methods and processes used in an evaluation of local journal subscriptions in a mental health trust and to suggest possible further areas of investigation were similar exercises to be undertaken again. Results from a user questionnaire were analysed along with e-journal usage statistics and data from local document supply activity. Journal reviews can yield surprising results. Carrying out a user survey is valuable in highlighting awareness of e-resources more generally and thus in providing evidence for marketing/information literacy initiatives. Future journal reviews should undertake impact analysis as potent evidence for continued expenditure on journals in this age of austerity. © 2011 The authors. Health Information and Libraries Journal © 2011 Health Libraries Group.

  19. Salmonella in meats, water, fruit and vegetables as disclosed from testing undertaken by Food Business Operators in Ireland from 2005 to 2009

    Directory of Open Access Journals (Sweden)

    Duggan Sharon

    2012-09-01

    Full Text Available Abstract Food Business Operators (FBO are responsible for the safety of the food they produce and in Ireland those under the regulatory control of the Department of Agriculture, Food and Marine are required to provide summary data on microbiological tests undertaken as part of their food safety controls. These data are provided to the National Reference Laboratory through the 25 private laboratories undertaking the testing. Results Over the five-year period Salmonella sp. was isolated from 0.7% of the 254,000 raw meat or raw meat products tested with the annual prevalence ranging from 0.5 to 1.1%. Poultry meats were consistently more contaminated than other meats with higher recovery rates in turkey (3.3%, duck (3.3%, and chicken (2.5% compared with meats of porcine (1.6%, ovine (0.2% and bovine origin (0.1%. Salmonella sp. was also isolated from 58 (0.06% of the 96,115 cooked or partially cooked meat and meat products tested during the reporting period with the annual percentage positive samples ranging from 0.01 to 0.16%. A total of 50 different serotypes were recovered from raw meats over this period with the greatest diversity found in poultry samples (n = 36. Four serotypes, Kentucky, Typhimurium, Agona and Derby accounted for over 70% of all isolates detected on FBO testing over the period 2005 to 2009. Conclusions Capturing microbiological data generated by Food Business Operators allows the regulatory sector access to a substantial amount of valuable data with the minimum financial outlay.

  20. Repeated measurements of cerebral blood flow in the left superior temporal gyrus reveal tonic hyperactivity in patients with auditory verbal hallucinations: A possible trait marker

    Directory of Open Access Journals (Sweden)

    Philipp eHoman

    2013-06-01

    Full Text Available Background: The left superior temporal gyrus (STG has been suggested to play a key role in auditory verbal hallucinations in patients with schizophrenia. Methods: Eleven medicated subjects with schizophrenia and medication-resistant auditory verbal hallucinations and 19 healthy controls underwent perfusion magnetic resonance imaging with arterial spin labeling. Three additional repeated measurements were conducted in the patients. Patients underwent a treatment with transcranial magnetic stimulation (TMS between the first 2 measurements. The main outcome measure was the pooled cerebral blood flow (CBF, which consisted of the regional CBF measurement in the left superior temporal gyrus (STG and the global CBF measurement in the whole brain.Results: Regional CBF in the left STG in patients was significantly higher compared to controls (p < 0.0001 and to the global CBF in patients (p < 0.004 at baseline. Regional CBF in the left STG remained significantly increased compared to the global CBF in patients across time (p < 0.0007, and it remained increased in patients after TMS compared to the baseline CBF in controls (p < 0.0001. After TMS, PANSS (p = 0.003 and PSYRATS (p = 0.01 scores decreased significantly in patients.Conclusions: This study demonstrated tonically increased regional CBF in the left STG in patients with schizophrenia and auditory hallucinations despite a decrease in symptoms after TMS. These findings were consistent with what has previously been termed a trait marker of auditory verbal hallucinations in schizophrenia.

  1. The inverted chevron plot measured by NMR relaxation reveals a native-like unfolding intermediate in acyl-CoA binding protein

    DEFF Research Database (Denmark)

    Teilum, Kaare; Poulsen, F. M.; Akke, M.

    2006-01-01

    under conditions favoring folding, for which the folding rate constant (k f) dominates the relaxation in stopped-flow kinetic measurements. Conversely, k f was determined under conditions favoring unfolding, for which k u dominates stopped-flow data. The rates determined by NMR therefore complement...

  2. Atmospheric measurements of Δ17O in CO2 in Göttingen, Germany reveal a seasonal cycle driven by biospheric uptake

    NARCIS (Netherlands)

    Hofmann, M. E. G.; Horvath, B.; Schneider, L.; Peters, W.; Schützenmeister, K.; Pack, A.

    2017-01-01

    The triple oxygen isotope composition of tropospheric CO2 might be a promising new tracer for terrestrial gross carbon fluxes. This notion is based on global box modeling of its abundance, and on highly challenging and therefore very sparse measurements of 16O, 17O and 18O in CO2 in the lower

  3. Time-measured phylogenies of gag, pol and env sequence data reveal the direction and time interval of HIV-1 transmission

    NARCIS (Netherlands)

    Rachinger, Andrea; Groeneveld, Paul H. P.; van Assen, Sander; Lemey, Philippe; Schuitemaker, Hanneke

    2011-01-01

    Objective: To investigate whether time-measured phylogenetic analysis of longitudinal viral sequences can establish the direction and timing of HIV-1 transmission in an epidemiologically linked transmission cluster of three homosexual men. Design: An HIV-1-infected homosexual man (patient 1) and his

  4. Patient burden of Sjögren’s: a comprehensive literature review revealing the range and heterogeneity of measures used in assessments of severity

    Science.gov (United States)

    Hammitt, Katherine M; Naegeli, April N; van den Broek, Remon W M; Birt, Julie A

    2017-01-01

    Context The severity of Sjögren’s syndrome has been evaluated using a wide variety of clinical measures and patient-reported outcomes (PROs). This may contribute to the lack of clarity concerning the burden of Sjögren’s from the patient perspective. Objective To perform a comprehensive peer-reviewed literature analysis of the patient aspects of Sjögren’s, focusing on PROs, to investigate the complexity underlying the evaluation of the syndrome and to elucidate the discordance between the different measures. Methods We searched Embase for articles published between January 2005 and September 2015. Research articles, clinical and diagnostic reviews, and validation studies with a focus on patient aspects of Sjögren’s were selected as the primary information source. Results 157 articles met the eligibility criteria. A wide variety of assessment measures used to evaluate glandular, extraglandular and functional domains were observed. Many different, non-validated Visual Analogue Scales, with a wide range of anchor words, were used in the quantification of Sjögren’s disease burden, impeding comparisons between studies. Relatively few clinical trials of drug therapies used validated scales: European League Against Rheumatism Sjögren’s Syndrome Patient Reported Index was used most often for symptom assessment and 36 Item Short Form Survey for quality of life (QoL). Conclusion A wide range and diversity of measures are used to evaluate the patient burden of Sjögren’s; most are not validated for use in this disease. PRO endpoints, validated specifically in Sjögren’s, that demonstrate improvement are needed. These measures should focus on QoL aspects important to patients and will most likely involve gauging change in function rather than patient-reported symptoms. PMID:28955493

  5. Measuring $\

    Energy Technology Data Exchange (ETDEWEB)

    Mitchell, Jessica Sarah [Univ. of Cambridge (United Kingdom)

    2011-01-01

    The MINOS Experiment consists of two steel-scintillator calorimeters, sampling the long baseline NuMI muon neutrino beam. It was designed to make a precise measurement of the ‘atmospheric’ neutrino mixing parameters, Δm2 atm. and sin2 (2 atm.). The Near Detector measures the initial spectrum of the neutrino beam 1km from the production target, and the Far Detector, at a distance of 735 km, measures the impact of oscillations in the neutrino energy spectrum. Work performed to validate the quality of the data collected by the Near Detector is presented as part of this thesis. This thesis primarily details the results of a vμ disappearance analysis, and presents a new sophisticated fitting software framework, which employs a maximum likelihood method to extract the best fit oscillation parameters. The software is entirely decoupled from the extrapolation procedure between the detectors, and is capable of fitting multiple event samples (defined by the selections applied) in parallel, and any combination of energy dependent and independent sources of systematic error. Two techniques to improve the sensitivity of the oscillation measurement were also developed. The inclusion of information on the energy resolution of the neutrino events results in a significant improvement in the allowed region for the oscillation parameters. The degree to which sin2 (2θ )= 1.0 could be disfavoured with the exposure of the current dataset if the true mixing angle was non-maximal, was also investigated, with an improved neutrino energy reconstruction for very low energy events. The best fit oscillation parameters, obtained by the fitting software and incorporating resolution information were: | Δm2| = 2.32+0.12 -0.08×10-3 eV2 and sin2 (2θ ) > 0.90(90% C.L.). The analysis provides the current world best measurement of the atmospheric neutrino mass

  6. Ratiometric measurements of adiponectin by mass spectrometry in bottlenose dolphins (Tursiops truncatus with iron overload reveal an association with insulin resistance and glucagon

    Directory of Open Access Journals (Sweden)

    Benjamin A Neely

    2013-09-01

    Full Text Available High molecular weight (HMW adiponectin levels are reduced in humans with type 2 diabetes and insulin resistance. Similar to humans with insulin resistance, managed bottlenose dolphins (Tursiops truncatus diagnosed with hemochromatosis (iron overload have higher levels of 2 h post-prandial plasma insulin than healthy controls. A parallel reaction monitoring assay for dolphin serum adiponectin was developed based on tryptic peptides identified by mass spectrometry. Using identified post-translational modifications, a differential measurement was constructed. Total and unmodified adiponectin levels were measured in sera from dolphins with (n=4 and without (n=5 iron overload. This measurement yielded total adiponectin levels as well as site specific percent unmodified adiponectin that may inversely correlate with HMW adiponectin. Differences in insulin levels between iron overload cases and controls were observed 2 h post-prandial, but not during the fasting state. Thus, post-prandial as well as fasting serum adiponectin levels were measured to determine whether adiponectin and insulin would follow similar patterns. There was no difference in total adiponectin or percent unmodified adiponectin from case or control fasting animals. There was no difference in post-prandial total adiponectin levels between case and control dolphins (mean ± S.D. at 763 ± 298 and 727 ± 291 pmol/ml, respectively (p = 0.91; however, percent unmodified adiponectin was significantly higher in post-prandial cases compared controls (30.0 ± 6.3 versus 17.0 ± 6.6%, respectively; p = 0.016. Interestingly, both total and percent unmodified adiponectin were correlated with glucagon levels in controls (r = 0.999, p < 0.001, but not in cases, which is possibly a reflection of insulin resistance. Although total adiponectin levels were not significantly different, the elevated percent unmodified adiponectin follows a trend similar to HMW adiponectin reported for humans with

  7. In vivo intracellular pH measurements in tobacco and Arabidopsis reveal an unexpected pH gradient in the endomembrane system.

    Science.gov (United States)

    Martinière, Alexandre; Bassil, Elias; Jublanc, Elodie; Alcon, Carine; Reguera, Maria; Sentenac, Hervé; Blumwald, Eduardo; Paris, Nadine

    2013-10-01

    The pH homeostasis of endomembranes is essential for cellular functions. In order to provide direct pH measurements in the endomembrane system lumen, we targeted genetically encoded ratiometric pH sensors to the cytosol, the endoplasmic reticulum, and the trans-Golgi, or the compartments labeled by the vacuolar sorting receptor (VSR), which includes the trans-Golgi network and prevacuoles. Using noninvasive live-cell imaging to measure pH, we show that a gradual acidification from the endoplasmic reticulum to the lytic vacuole exists, in both tobacco (Nicotiana tabacum) epidermal (ΔpH -1.5) and Arabidopsis thaliana root cells (ΔpH -2.1). The average pH in VSR compartments was intermediate between that of the trans-Golgi and the vacuole. Combining pH measurements with in vivo colocalization experiments, we found that the trans-Golgi network had an acidic pH of 6.1, while the prevacuole and late prevacuole were both more alkaline, with pH of 6.6 and 7.1, respectively. We also showed that endosomal pH, and subsequently vacuolar trafficking of soluble proteins, requires both vacuolar-type H(+) ATPase-dependent acidification as well as proton efflux mediated at least by the activity of endosomal sodium/proton NHX-type antiporters.

  8. Comparison of multiple non-invasive methods of measuring cardiac output during pregnancy reveals marked heterogeneity in the magnitude of cardiac output change between women.

    Science.gov (United States)

    Petersen, John W; Liu, Jing; Chi, Yueh-Yun; Lingis, Melissa; Williams, R Stan; Rhoton-Vlasak, Alice; Segal, Mark S; Conrad, Kirk P

    2017-04-01

    Various non-invasive methods are available to measure cardiac output (CO) during pregnancy. We compared serial measures of CO using various methods to determine which provided the least variability. Ten patients with spontaneous pregnancy had estimation of CO at baseline prior to becoming pregnant and at the end of the first and third trimesters. Echocardiographic data were used to estimate CO using the Teichholz method, Simpson's biplane method, and the Doppler determined velocity time integral (VTI) method. In addition, a Bioz Dx device was used to estimate CO by impedance cardiography. CO estimated with the VTI method had the lowest beat-to-beat variability. CO estimated with the VTI method was higher than CO estimated with the 2D-Teichholz method and Simpson's method. The percent change in CO during pregnancy was similar for all echo methods (VTI, Teichholz, and Simpson's biplane). Baseline CO determined with impedance cardiography was higher than CO determined with the VTI method. However, change in CO during pregnancy was significantly lower when measured with impedance cardiography. There was marked heterogeneity in the degree of rise in CO during the first trimester (-3 to 55%). The wide variation in the gestational rise in CO was unexpected, and at least in part secondary to variable increase in heart rate. We recommend the use of the Doppler determined VTI method for the estimation of CO in pregnancy. © 2017 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

  9. Electrical transport characteristics of Sn/p-Si schottky contacts revealed from I-V-T and C-V-T measurements

    Energy Technology Data Exchange (ETDEWEB)

    Karatas, S. [Department of Physics, Faculty of Sciences and Arts, University of Kahramanmaras Suetcue Imam, 46100 Kahramanmaras (Turkey)]. E-mail: skaratas@ksu.edu.tr; Altindal, S. [Department of Physics, Faculty of Arts and Sciences, Gazi University, 06500 Ankara (Turkey); Tueruet, A. [Department of Physics, Faculty of Sciences and Arts, Atatuerk University, 25240 Erzurum (Turkey); Cakar, M. [Department of Chemistry, Faculty of Sciences and Arts, University of Kahramanmaras Suetcue Imam, 46100 Kahramanmaras (Turkey)

    2007-04-15

    The current-voltage (I-V) and capacitance-voltage (C-V) characteristics of metal-semiconductor (Sn/p-Si) Schottky contacts were measured in the temperature range 150-400 K. The effect of the temperature on the series resistances R {sub S}, ideality factors n, the barrier height {phi} {sub b} and interface state density N {sub SS} obtained from the I-V and C-V characteristics were investigated. The n, {phi} {sub b}, R {sub S}, and N {sub SS} values were seen to be strongly temperature dependent. The ideality factors, series resistances and interface state densities decreased with increasing temperature for all diodes and the values of n, R {sub S}, and N {sub SS} obtained from I-V and C-V measurements were found in the ranges of 2.024-1.108, 2.083-1.121; 79.508-33.397 {omega}; and 2.14x10{sup 13}-0.216x10{sup 13} cm{sup 2} eV{sup -1}, 2.277x10{sup 13}-0.254x10{sup 13} cm{sup 2} eV{sup -1}, respectively. The temperature dependence of energy distribution of interface state density (N {sub SS}) profiles has been determined from I-V measurements by taking into account the bias dependence of the effective barrier height and ideality factor.

  10. The variation of dust content with intrinsic galaxy properties: revealing strong dust biases in many commonly-used galaxy property measurements

    Science.gov (United States)

    Devour, Brian; Bell, Eric F.

    2018-01-01

    Dust strongly affects many observations of galaxy properties, and quantifying galaxy dust content and correcting for its effects is a delicate and often uncertain task. In particular, both the impact of dust on commonly-used metrics of galaxy structure and the variation of dust content with intrinsic galaxy properties are poorly quantified. The inclination dependence of dust attenuation is a powerful tool to quantify dust amounts and the effects of dust on galaxy property measurements; this requires the construction of dust and inclination-independent selection techniques to isolate samples of intrinsically similar galaxies for study. To this end we construct dust and inclination-independent measurements of galaxy mass and star formation rate using dust-penetrated infrared datasets, and we develop novel dust and inclination-independent galaxy ‘linear’ size and concentration measurements by collapsing the light distribution in the near-infrared onto the major axis. With these new metrics we select a sample of Milky Way analog galaxies with similar stellar masses, star formation rates, and linear sizes and concentrations. These galaxies - identical save for their orientation - show strong systematic dust and inclination dependence in their Sérsic index, concentration, half-light radius, luminosity, (dust-corrected!) star formation rate and metallicitity, and spectral classification. We use these new metrics to study the variation in relative face-on to edge-on attenuation as a function of intrinsic stellar mass, star formation rate, and linear size and concentration. We find that, if one accounts for geometric and radiative transfer effects, the complex patterns of variation in relative attenuation can be reproduced by simple scaling relation-based dust density models in which dust optical depth is set primarily by gas density and metallicity.

  11. In-vivo nonlinear optical microscopy (NLOM of epithelial-connective tissue interface (ECTI reveals quantitative measures of neoplasia in hamster oral mucosa.

    Directory of Open Access Journals (Sweden)

    Rahul Pal

    Full Text Available The epithelial-connective tissue interface (ECTI plays an integral role in epithelial neoplasia, including oral squamous cell carcinoma (OSCC. This interface undergoes significant alterations due to hyperproliferating epithelium that supports the transformation of normal epithelium to precancers and cancer. We present a method based on nonlinear optical microscopy to directly assess the ECTI and quantify dysplastic alterations using a hamster model for oral carcinogenesis. Neoplastic and non-neoplastic normal mucosa were imaged in-vivo by both multiphoton autofluorescence microscopy (MPAM and second harmonic generation microscopy (SHGM to obtain cross-sectional reconstructions of the oral epithelium and lamina propria. Imaged sites were biopsied and processed for histopathological grading and measurement of ECTI parameters. An ECTI shape parameter was calculated based on deviation from the linear geometry (ΔLinearity seen in normal mucosa was measured using MPAM-SHGM and histology. The ECTI was readily visible in MPAM-SHGM and quantitative shape analysis showed ECTI deformation in dysplasia but not in normal mucosa. ΔLinearity was significantly (p < 0.01 higher in dysplasia (0.41±0.24 than normal (0.11±0.04 as measured in MPAM-SHGM and results were confirmed in histology which showed similar trends in ΔLinearity. Increase in ΔLinearity was also statistically significant for different grades of dysplasia. In-vivo ΔLinearity measurement alone from microscopy discriminated dysplasia from normal tissue with 87.9% sensitivity and 97.6% specificity, while calculations from histology provided 96.4% sensitivity and 85.7% specificity. Among other quantifiable architectural changes, a progressive statistically significant increase in epithelial thickness was seen with increasing grade of dysplasia. MPAM-SHGM provides new noninvasive ways for direct characterization of ECTI which may be used in preclinical studies to investigate the role of this

  12. Patient burden of Sjögren’s: a comprehensive literature review revealing the range and heterogeneity of measures used in assessments of severity

    OpenAIRE

    Hammitt, Katherine M; Naegeli, April N; van den Broek, Remon W M; Birt, Julie A

    2017-01-01

    Context The severity of Sjögren’s syndrome has been evaluated using a wide variety of clinical measures and patient-reported outcomes (PROs). This may contribute to the lack of clarity concerning the burden of Sjögren’s from the patient perspective. Objective To perform a comprehensive peer-reviewed literature analysis of the patient aspects of Sjögren’s, focusing on PROs, to investigate the complexity underlying the evaluation of the syndrome and to elucidate the discordance between the diff...

  13. Comparison of the Calibration Standards of Three Commercially Available Multiplex Kits for Human Cytokine Measurement to WHO Standards Reveals Striking Differences

    Directory of Open Access Journals (Sweden)

    Ivan M. Roitt

    2008-01-01

    Full Text Available Serum parameters as indicators for the efficacy of therapeutic drugs are currently in the focus of intensive research. The induction of certain cytokines (or cytokine patterns is known to be related to the status of the immune response e.g. in regulating the TH1/TH2 balance. Regarding their potential value as surrogate parameters in clinical trials and subsequently for the assignment of treatment effi cacy, the accurate and reliable determination of cytokines in patient serum is mandatory. Because serum samples are precious and limited, test methods—like the xMAP multiplex technology—that allow for the simultaneous determination of a variety of cytokines from only a small sample aliquot, can offer great advantages.We here have compared multiplex kits from three different manufactures and found striking differences upon standardizing using WHO standards for selected cytokines. We therefore extended our xMAP multiplex measurements investigations to an ex-vivo situation by testing serum samples and found that the cytokine amounts measured was critically influenced by the actual kit used. The presented data indicate that statements regarding the quantitive determination of cytokines—and therefore their use as biomarkers—in serum samples have to be interpreted with caution.

  14. In-vivo nonlinear optical microscopy (NLOM) of epithelial-connective tissue interface (ECTI) reveals quantitative measures of neoplasia in hamster oral mucosa.

    Science.gov (United States)

    Pal, Rahul; Yang, Jinping; Ortiz, Daniel; Qiu, Suimin; Resto, Vicente; McCammon, Susan; Vargas, Gracie

    2015-01-01

    The epithelial-connective tissue interface (ECTI) plays an integral role in epithelial neoplasia, including oral squamous cell carcinoma (OSCC). This interface undergoes significant alterations due to hyperproliferating epithelium that supports the transformation of normal epithelium to precancers and cancer. We present a method based on nonlinear optical microscopy to directly assess the ECTI and quantify dysplastic alterations using a hamster model for oral carcinogenesis. Neoplastic and non-neoplastic normal mucosa were imaged in-vivo by both multiphoton autofluorescence microscopy (MPAM) and second harmonic generation microscopy (SHGM) to obtain cross-sectional reconstructions of the oral epithelium and lamina propria. Imaged sites were biopsied and processed for histopathological grading and measurement of ECTI parameters. An ECTI shape parameter was calculated based on deviation from the linear geometry (ΔLinearity) seen in normal mucosa was measured using MPAM-SHGM and histology. The ECTI was readily visible in MPAM-SHGM and quantitative shape analysis showed ECTI deformation in dysplasia but not in normal mucosa. ΔLinearity was significantly (p epithelial thickness was seen with increasing grade of dysplasia. MPAM-SHGM provides new noninvasive ways for direct characterization of ECTI which may be used in preclinical studies to investigate the role of this interface in early transformation. Further development of the method may also lead to new diagnostic approaches to differentiate non-neoplastic tissue from precancers and neoplasia, possibly with other cellular and layer based indicators of abnormality.

  15. Using Continuous In-situ Measurement of Fluorescence to Reveal Hot Spots and Hot Moments of Dissolved Organic Matter Dynamics in a Forested Watershed

    Science.gov (United States)

    Ryan, K. A.; Hosen, J. D.; Raymond, P. A.; Stubbins, A.; Shanley, J. B.

    2017-12-01

    River systems serve as net carbon exporters from land to the ocean, fueling downstream aquatic ecosystem food webs. Fluorescence signatures of aquatic organic matter can be used as a proxy for dissolved organic carbon (DOC) concentration and can characterize DOC composition, reactivity, and source to improve our understanding of ecological processes. In-situ measurement of fluorescence using fifteen-minute interval data logging allows greater temporal resolution than laboratory studies. However, in-situ data must be corrected for interferences from temperature, absorbance and turbidity changes occurring in the field. We installed multiparameter water quality sondes (Eureka Mantas) and in-situ fluorometers (Turner Designs Cyclops) at sites nested within streams and riparian zones in the Sleepers River Research Watershed in Vermont in 2017. We coupled these measurements with simultaneous intensive field sampling campaigns and laboratory analysis of DOC and fluorescence Excitation-Emission Matrices. The data loggers from the nested sites recorded fluorescence peaks responding to discharge events and tracked changes in fluorescence occurring from upstream to downstream sites. Laboratory results confirm a nonlinear, hysteretic relationship between discharge and DOC where peak DOC lags peak discharge. This hysteresis is predicted to be controlled by multiple flow paths and DOC sources (i.e. groundwater, overland flow). We conclude that continuous in-situ records of river water fluorescence can be used to inform ecological processes and test new hypotheses concerning dissolved organic matter dynamics in watersheds.

  16. Different emissive states in the bulk and at the surface of methylammonium lead bromide perovskite revealed by two-photon micro-spectroscopy and lifetime measurements

    Directory of Open Access Journals (Sweden)

    Khadga Jung Karki

    2016-07-01

    Full Text Available Two photon photoluminescence (2PPL from single crystals of methyl ammonium lead bromide (CH3NH3PbBr3, MAPbBr3 is studied. We observe two components in the 2PPL spectra, which we assign to the photoluminescence (PL from the carrier recombination at the band edge and the recombination due to self-trapping of excitons. The PL Stokes shift of self-trapped excitons is about 100 meV from the band-gap energy. Our measurements show that about 15% of the total PL from regions about 40 μm deep inside the crystal is due to the emission from self-trapped exciton. This contribution increases to about 20% in the PL from the regions close to the surface. Time resolved measurements of 2PPL show that the PL due to band-edge recombination has a life time of about 8 ns while the PL lifetime of self-trapped excitons is in the order of 100 ns. Quantification of self-trapped excitons in the materials used in photovoltaics is important as such excitons hinder charge separation. As our results also show that an appreciable fraction of photo-generated carriers get trapped, the results are important in rational design of photovoltaics. On the other hand, our results also show that the self-trapped excitons broaden the emission spectrum, which may be useful in designing broadband light emitting devices.

  17. Complexities of bloom dynamics in the toxic dinoflagellate Alexandrium fundyense revealed through DNA measurements by imaging flow cytometry coupled with species-specific rRNA probes

    Science.gov (United States)

    Brosnahan, Michael L.; Farzan, Shahla; Keafer, Bruce A.; Sosik, Heidi M.; Olson, Robert J.; Anderson, Donald M.

    2014-05-01

    Measurements of the DNA content of different protist populations can shed light on a variety of processes, including cell division, sex, prey ingestion, and parasite invasion. Here, we modified an Imaging FlowCytobot (IFCB), a custom-built flow cytometer that records images of microplankton, to measure the DNA content of large dinoflagellates and other high-DNA content species. The IFCB was also configured to measure fluorescence from Cy3-labeled rRNA probes, aiding the identification of Alexandrium fundyense (syn. A. tamarense Group I), a photosynthetic dinoflagellate that causes paralytic shellfish poisoning (PSP). The modified IFCB was used to analyze samples from the development, peak and termination phases of an inshore A. fundyense bloom (Salt Pond, Eastham, MA, USA), and from a rare A. fundyense ‘red tide’ that occurred in the western Gulf of Maine, offshore of Portsmouth, NH (USA). Diploid or G2 phase (‘2C’) A. fundyense cells were frequently enriched at the near-surface, suggesting an important role for aggregation at the air-sea interface during sexual events. Also, our analysis showed that large proportions of A. fundyense cells in both the Salt Pond and red tide blooms were planozygotes during bloom decline, highlighting the importance of sexual fusion to bloom termination. At Salt Pond, bloom decline also coincided with a dramatic rise in infections by the parasite genus Amoebophrya. The samples that were most heavily infected contained many large cells with higher DNA-associated fluorescence than 2C vegetative cells, but these cells' nuclei were also frequently consumed by Amoebophrya trophonts. Neither large cell size nor increased DNA-associated fluorescence could be replicated by infecting an A. fundyense culture of vegetative cells. Therefore, we attribute these characteristics of the large Salt Pond cells to planozygote maturation rather than Amoebophrya infection, though an interaction between infection and planozygote maturation may

  18. Anisotropic phase diagram and spin fluctuations of the hyperkagome magnet Gd3Ga5O12 as revealed by sound velocity measurements

    Science.gov (United States)

    Rousseau, Alexandre; Parent, Jean-Michel; Quilliam, Jeffrey A.

    2017-08-01

    Sound velocity and attenuation measurements on the frustrated garnet material Gd3Ga5O12 (GGG) are presented as a function of field and temperature, with two different magnetic field orientations: [100 ] and [110 ] . We demonstrate that the phase diagram is highly anisotropic, with two distinct field-induced ordered phases for H ||[110 ] and only one for H ||[100 ] . Extensive lattice softening is found to occur at low fields, which can be associated with spin fluctuations. However, deep within the spin liquid phase a low-temperature stiffening of the lattice and reduced attenuation provide evidence for a spin gap which may be related to short-range antiferromagnetic correlations over minimal ten-spin loops.

  19. An optimized method for measuring hypocretin-1 peptide in the mouse brain reveals differential circadian regulation of hypocretin-1 levels rostral and caudal to the hypothalamus

    DEFF Research Database (Denmark)

    Justinussen, Jessica; Holm, A; Kornum, B R

    2015-01-01

    The hypocretin/orexin system regulates, among other things, sleep and energy homeostasis. The system is likely regulated by both homeostatic and circadian mechanisms. Little is known about local differences in the regulation of hypocretin activity. The aim of this study was to establish...... an optimized peptide quantification method for hypocretin-1 extracted from different mouse brain areas and use this method for investigating circadian fluctuations of hypocretin-1 levels in these areas. The results show that hypocretin-1 peptide can be extracted from small pieces of intact tissue......, with sufficient yield for measurements in a standard radioimmunoassay. Utilizing the optimized method, it was found that prepro-hypocretin mRNA and peptide show circadian fluctuations in the mouse brain. This study further demonstrates that the hypocretin-1 peptide level in the frontal brain peaks during dark...

  20. Compaction and gas loss in welded pyroclastic deposits as revealed by porosity, permeability, and electrical conductivity measurements of the Shevlin Park Tuff

    Science.gov (United States)

    Wright, Heather M.; Cashman, Katharine V.

    2014-01-01

    Pyroclastic flows produced by large volcanic eruptions commonly densify after emplacement. Processes of gas escape, compaction, and welding in pyroclastic-flow deposits are controlled by the physical and thermal properties of constituent material. Through measurements of matrix porosity, permeability, and electrical conductivity, we provide a framework for understanding the evolution of pore structure during these processes. Using data from the Shevlin Park Tuff in central Oregon, United States, and from the literature, we find that over a porosity range of 0%–70%, matrix permeability varies by almost 10 orders of magnitude (from 10–20 to 10–11 m2), with over three orders of magnitude variation at any given porosity. Part of the variation at a given porosity is due to permeability anisotropy, where oriented core samples indicate higher permeabilities parallel to foliation (horizontally) than perpendicular to foliation (vertically). This suggests that pore space is flattened during compaction, creating anisotropic crack-like networks, a geometry that is supported by electrical conductivity measurements. We find that the power law equation: k1 = 1.3 × 10–21 × ϕ5.2 provides the best approximation of dominant horizontal gas loss, where k1 = permeability, and ϕ = porosity. Application of Kozeny-Carman fluid-flow approximations suggests that permeability in the Shevlin Park Tuff is controlled by crack- or disk-like pore apertures with minimum widths of 0.3 and 7.5 μm. We find that matrix permeability limits compaction over short times, but deformation is then controlled by competition among cooling, compaction, water resorption, and permeable gas escape. These competing processes control the potential for development of overpressure (and secondary explosions) and the degree of welding in the deposit, processes that are applicable to viscous densification of volcanic deposits in general. Further, the general relationships among porosity, permeability, and

  1. Air-sea interaction regimes in the sub-Antarctic Southern Ocean and Antarctic marginal ice zone revealed by icebreaker measurements

    Science.gov (United States)

    Yu, Lisan; Jin, Xiangze; Schulz, Eric W.; Josey, Simon A.

    2017-08-01

    This study analyzed shipboard air-sea measurements acquired by the icebreaker Aurora Australis during its off-winter operation in December 2010 to May 2012. Mean conditions over 7 months (October-April) were compiled from a total of 22 ship tracks. The icebreaker traversed the water between Hobart, Tasmania, and the Antarctic continent, providing valuable in situ insight into two dynamically important, yet poorly sampled, regimes: the sub-Antarctic Southern Ocean and the Antarctic marginal ice zone (MIZ) in the Indian Ocean sector. The transition from the open water to the ice-covered surface creates sharp changes in albedo, surface roughness, and air temperature, leading to consequential effects on air-sea variables and fluxes. Major effort was made to estimate the air-sea fluxes in the MIZ using the bulk flux algorithms that are tuned specifically for the sea-ice effects, while computing the fluxes over the sub-Antarctic section using the COARE3.0 algorithm. The study evidenced strong sea-ice modulations on winds, with the southerly airflow showing deceleration (convergence) in the MIZ and acceleration (divergence) when moving away from the MIZ. Marked seasonal variations in heat exchanges between the atmosphere and the ice margin were noted. The monotonic increase in turbulent latent and sensible heat fluxes after summer turned the MIZ quickly into a heat loss regime, while at the same time the sub-Antarctic surface water continued to receive heat from the atmosphere. The drastic increase in turbulent heat loss in the MIZ contrasted sharply to the nonsignificant and seasonally invariant turbulent heat loss over the sub-Antarctic open water.Plain Language SummaryThe icebreaker Aurora Australis is a research and supply vessel that is regularly chartered by the Australian Antarctic Division during the southern summer to operate in waters between Hobart, Tasmania, and Antarctica. The vessel serves as the main lifeline to three permanent research stations on the

  2. THE BURSTY STAR FORMATION HISTORIES OF LOW-MASS GALAXIES AT 0.4 < z < 1 REVEALED BY STAR FORMATION RATES MEASURED FROM H β AND FUV

    Energy Technology Data Exchange (ETDEWEB)

    Guo, Yicheng; Faber, S. M.; Koo, David C.; Krumholz, Mark R.; Barro, Guillermo; Yesuf, Hassen [UCO/Lick Observatory, Department of Astronomy and Astrophysics, University of California, Santa Cruz, CA (United States); Rafelski, Marc; Gardner, Jonathan P.; Pacifici, Camilla [Goddard Space Flight Center, Code 665, Greenbelt, MD (United States); Trump, Jonathan R. [Department of Astronomy and Astrophysics and Institute for Gravitation and the Cosmos, Pennsylvania State University, University Park, PA (United States); Willner, S. P. [Harvard-Smithsonian Center for Astrophysics, Cambridge, MA (United States); Amorín, Ricardo [INAF-Osservatorio Astronomico di Roma, Monte Porzio Catone (Italy); Bell, Eric F. [Department of Astronomy, University of Michigan, Ann Arbor, MI (United States); Gawiser, Eric [Department of Physics and Astronomy, Rutgers University, New Brunswick, NJ (United States); Hathi, Nimish P. [Aix Marseille Université, CNRS, LAM (Laboratoire d’Astrophysique de Marseille) UMR 7326, Marseille (France); Koekemoer, Anton M.; Ravindranath, Swara [Space Telescope Science Institute, Baltimore, MD (United States); Pérez-González, Pablo G. [Departamento de Astrofísica, Facultad de CC. Físicas, Universidad Complutense de Madrid, E-28040 Madrid (Spain); Reddy, Naveen [Department of Physics and Astronomy, University of California, Riverside, CA (United States); Teplitz, Harry I., E-mail: ycguo@ucolick.org [Infrared Processing and Analysis Center, Caltech, Pasadena, CA 91125 (United States)

    2016-12-10

    We investigate the burstiness of star formation histories (SFHs) of galaxies at 0.4 <  z  < 1 by using the ratio of star formation rates (SFRs) measured from H β and FUV (1500 Å) (H β -to-FUV ratio). Our sample contains 164 galaxies down to stellar mass ( M {sub *}) of 10{sup 8.5} M {sub ⊙} in the CANDELS GOODS-N region, where Team Keck Redshift Survey Keck/DEIMOS spectroscopy and Hubble Space Telescope /WFC3 F275W images from CANDELS and Hubble Deep UV Legacy Survey are available. When the ratio of H β - and FUV-derived SFRs is measured, dust extinction correction is negligible (except for very dusty galaxies) with the Calzetti attenuation curve. The H β -to-FUV ratio of our sample increases with M {sub *} and SFR. The median ratio is ∼0.7 at M {sub *} ∼ 10{sup 8.5} M {sub ⊙} (or SFR ∼ 0.5 M {sub ⊙} yr{sup −1}) and increases to ∼1 at M {sub *} ∼ 10{sup 10} M {sub ⊙} (or SFR ∼ 10 M {sub ⊙} yr{sup −1}). At M {sub *} < 10{sup 9.5} M {sub ⊙}, our median H β -to-FUV ratio is lower than that of local galaxies at the same M {sub *}, implying a redshift evolution. Bursty SFH on a timescale of a few tens of megayears on galactic scales provides a plausible explanation for our results, and the importance of the burstiness increases as M {sub *} decreases. Due to sample selection effects, our H β -to-FUV ratio may be an upper limit of the true value of a complete sample, which strengthens our conclusions. Other models, e.g., non-universal initial mass function or stochastic star formation on star cluster scales, are unable to plausibly explain our results.

  3. Effect of aging on phosphate metabolites of rat brain as revealed by the in vivo and in vitro 31P NMR measurements

    International Nuclear Information System (INIS)

    Liu, Hsiuchih; Chi, Chinwen; Liu, Tsungyun; Liu, Lianghui; Luh, Wenming; Hsieh, Changhuain; Wu, Wenguey

    1991-01-01

    Changes of phosphate metabolism in brains of neonate, weaning and adult rats were compared using both in vivo and in vitro nuclear magnetic resonance spectra. Ratios of phosphocreatine/nucleoside triphosphate (PCr/NTP) were the same in neonatal brain in both in vivo and in vitro studies, but not in weaning and adult brains. This discrepancy may have resulted from extended cerebral hypoxia due to slowed freezing of the brain by the increased skull thickness and brain mass in the weaning and adult rats. Variations of in vitro extraction condition for this age-related study may lead to systematic errors in the adult rats. Nevertheless, the phosphomonoester/nucleoside triphosphate (PME/NTP) ratios in extracts of brain from neonatal rats were higher than those obtained in vivo. In addition, the glycerophosphorylethanolamine plus glycerophosphorylcholine/nucleoside triphosphate (GPE+GPC/NTP) ratios, which were not measurable in vivo, showed age-dependent increase in extracts of rat brain. Some of the phosphomonoester and phosphodiester molecules in rat brain may be undetectable in in vivo NMR analysis because of their interaction with cellular components. The total in vitro GPE and GPC concentration in brain from neonatal rat was estimated to be 0.34 mmole/g wet tissue

  4. An optimized method for measuring hypocretin-1 peptide in the mouse brain reveals differential circadian regulation of hypocretin-1 levels rostral and caudal to the hypothalamus.

    Science.gov (United States)

    Justinussen, J L; Holm, A; Kornum, B R

    2015-12-03

    The hypocretin/orexin system regulates, among other things, sleep and energy homeostasis. The system is likely regulated by both homeostatic and circadian mechanisms. Little is known about local differences in the regulation of hypocretin activity. The aim of this study was to establish an optimized peptide quantification method for hypocretin-1 extracted from different mouse brain areas and use this method for investigating circadian fluctuations of hypocretin-1 levels in these areas. The results show that hypocretin-1 peptide can be extracted from small pieces of intact tissue, with sufficient yield for measurements in a standard radioimmunoassay. Utilizing the optimized method, it was found that prepro-hypocretin mRNA and peptide show circadian fluctuations in the mouse brain. This study further demonstrates that the hypocretin-1 peptide level in the frontal brain peaks during dark as does prepro-hypocretin mRNA in the hypothalamus. However, in midbrain and brainstem tissue caudal to the hypothalamus, there was less circadian fluctuation and a tendency for higher levels during the light phase. These data suggest that regulation of the hypocretin system differs between brain areas. Copyright © 2015 IBRO. Published by Elsevier Ltd. All rights reserved.

  5. Atmospheric boundary layer structures associated with the Ora del Garda wind in the Alps as revealed from airborne and surface measurements

    Science.gov (United States)

    Laiti, Lavinia; Zardi, Dino; de Franceschi, Massimiliano; Rampanelli, Gabriele

    2013-10-01

    The paper investigates a coupled lake-breeze and valley-wind system, known as Ora del Garda. The latter typically originates on clear-sky days over the northern shore of Lake Garda in the Alps. After channelling into the nearby Sarca Valley and Lakes Valley, this airflow finally breaks out, through an elevated saddle, into the adjacent Adige Valley, where it strongly interacts with the local valley wind. Two flights of an instrumented motorglider explored, under different synoptic conditions, the thermal structure of the atmospheric boundary layer (ABL) associated with this wind at selected vertical sections-namely over the lake shore, at mid-valley, and at the junction with the Adige Valley. Data from airborne measurements, as well as from weather stations disseminated along the valley floor, provided the basis for mapping 3D fields of potential temperature over high-resolution grids by means of a Residual Kriging (RK) technique. This representation allowed the identification of site-specific ABL features associated with the Ora del Garda. In particular, a typical daytime coastal-breeze structure is detected in the lake shore region, where the advection of colder air tends to stabilize the atmosphere throughout the ABL depth. Mid-valley vertical profiles from both flights display shallow convective mixed layers, surmounted by deeper weakly stable layers. On the other hand, RK-gridded temperature maps show cross-valley thermal asymmetries, amenable to the complex topography and to the inhomogeneous surface coverage, as well as to a curvature of the valley axis. Finally, in the area where the upper Lakes Valley joins the Adige Valley, specific features associated with the complex interaction between the Ora del Garda and the local up-valley wind are found.

  6. Long-term behavior of the Kelvin waves revealed by CHAMP/GPS RO measurements and their effects on the tropopause structure

    Directory of Open Access Journals (Sweden)

    M. Venkat Ratnam

    2006-07-01

    Full Text Available The vertical and temporal variations of Kelvin waves and the associated effects on the tropical tropopause were studied using long-term (from May 2001 to October 2005 CHAMP/GPS (CHAllenging Mini satellite Payload/Global Positioning System radio occultation (RO measurements. The periods of these waves were found to be varying in between 10 and 15 days, with vertical wavelengths 5–8 km. These variations clearly show eastward phase propagation in the time-longitude section and eastward phase tilts with height in altitude-longitude, displaying the characteristics of Kelvin waves. The peak variance in the temperature is found over the Indian Ocean and into the western Pacific within the broad region of the equator. Kelvin wave amplitudes were found significantly enhanced in the eastward shear of the quasi-biennial oscillation (QBO and are confined in and around the tropopause during westward phase of QBO, where it extends between 17 and 25 km during the eastward phase of QBO and is damped away above, consistent with earlier reported results. The amplitudes are increasing during the months of Northern Hemisphere winter and sometimes they are highly sporadic in nature. Seasonal and inter-annual variations in the Kelvin wave amplitudes near the tropical tropopause coincide exactly with the tropopause height and temperature, with a sharp tropopause during maximum Kelvin wave activity. A clear annual oscillation, along with a month-to-month coincidence is evident most of the time in both the tropopause height and Kelvin wave activity, with maximum and minimum Kelvin wave amplitudes during the Northern Hemisphere winter and summer, respectively. In addition, a signature of quasi-biennial oscillation (QBO in the tropopause structure is also seen in long-term tropopause variations, although the amplitudes are less when compared to the annual oscillation. In the westward phase of QBO (during strong Kelvin wave activity at 20km (in 2001–2002 winter and

  7. ACTIVITIES OF THE ADMINISTRATION OF FEDERAL SERVICE FOR SURVEILLANCE ON CONSUMER RIGHTS PROTECTION AND HUMAN WELL-BEING IN KHABAROVSKY KRAI IN CONDITIONS OF THE FUKUSHIMA ACCIDENT AND MEASURES UNDERTAKEN TO PROTECT THE TERRITORY AND POPULATION THE REGION

    Directory of Open Access Journals (Sweden)

    V. A. Ott

    2011-01-01

    Full Text Available The article analyzes activities of the Administration of Federal Service for Surveillance on Consumer Rights Protection and Human Well-being in Khabarovsky Krai and the Federal Health Organization "Center of Hygiene and Epidemiology in Khabarovsky Krai" in the situation related to the Fukushima accident in Japan

  8. Orbital tumor revealing a systemic sarcoidosis.

    Directory of Open Access Journals (Sweden)

    Samia Hannanachi Sassi

    2015-03-01

    Full Text Available Ocular involvement is seen in approximately 25% of patients with sarcoidosis. Uveitis is the most common ocular manifestation, but sarcoidosis may involve any part of the eye. Orbital manifestations of sarcoidosis are uncommon with few series in the literature. A 65-year-old woman presented with redness of the right eye and painless, unilateral eyelid swelling. Orbital scanning revealed mass infiltrating the soft tissue of the inferior right orbital quadrant. Biopsy results showed nodular, noncaseating granulomas consistent with sarcoidosis. The complete systemic workup revealed systemic manifestations of sarcoidosis at the time of examination with hilar and mediastinal lymphadenopathies noted on CT scan. The orbital surgical treatment was followed by systemic prednisone therapy with good response. Although rare, orbital sarcoidosis must be considered in the evaluation of orbital tumors in elderly patients. A search for systemic findings should be undertaken and appropriate therapy should be instituted.

  9. Econometric models of road use, accidents, and road investment decisions. Volume 1 : introductory overview, the barely revealed preference behind road investment priorities (essay 1), measuring the contribution of randomness, exposure, weather, and daylig

    Science.gov (United States)

    1999-11-01

    This volume contains the forst part of the author's PhD dissertation, and includes an introductory overview as well as two essays. The first essay entitled "The barely revealed preference behind road investment priorities," co-authored by Rune Elvik,...

  10. Quantitative flux analysis reveals folate-dependent NADPH production

    Science.gov (United States)

    Fan, Jing; Ye, Jiangbin; Kamphorst, Jurre J.; Shlomi, Tomer; Thompson, Craig B.; Rabinowitz, Joshua D.

    2014-06-01

    ATP is the dominant energy source in animals for mechanical and electrical work (for example, muscle contraction or neuronal firing). For chemical work, there is an equally important role for NADPH, which powers redox defence and reductive biosynthesis. The most direct route to produce NADPH from glucose is the oxidative pentose phosphate pathway, with malic enzyme sometimes also important. Although the relative contribution of glycolysis and oxidative phosphorylation to ATP production has been extensively analysed, similar analysis of NADPH metabolism has been lacking. Here we demonstrate the ability to directly track, by liquid chromatography-mass spectrometry, the passage of deuterium from labelled substrates into NADPH, and combine this approach with carbon labelling and mathematical modelling to measure NADPH fluxes. In proliferating cells, the largest contributor to cytosolic NADPH is the oxidative pentose phosphate pathway. Surprisingly, a nearly comparable contribution comes from serine-driven one-carbon metabolism, in which oxidation of methylene tetrahydrofolate to 10-formyl-tetrahydrofolate is coupled to reduction of NADP+ to NADPH. Moreover, tracing of mitochondrial one-carbon metabolism revealed complete oxidation of 10-formyl-tetrahydrofolate to make NADPH. As folate metabolism has not previously been considered an NADPH producer, confirmation of its functional significance was undertaken through knockdown of methylenetetrahydrofolate dehydrogenase (MTHFD) genes. Depletion of either the cytosolic or mitochondrial MTHFD isozyme resulted in decreased cellular NADPH/NADP+ and reduced/oxidized glutathione ratios (GSH/GSSG) and increased cell sensitivity to oxidative stress. Thus, although the importance of folate metabolism for proliferating cells has been long recognized and attributed to its function of producing one-carbon units for nucleic acid synthesis, another crucial function of this pathway is generating reducing power.

  11. TypeScript revealed

    CERN Document Server

    Maharry, Dan

    2013-01-01

    TypeScript Revealed is a quick 100-page guide to Anders Hejlsberg's new take on JavaScript. With this brief, fast-paced introduction to TypeScript, .NET, Web and Windows 8 application developers who are already familiar with JavaScript will easily get up to speed with TypeScript and decide whether or not to start incorporating it into their own development. TypeScript is 'JavaScript for Application-scale development'; a superset of JavaScript that brings to it an additional object-oriented-like syntax familiar to .NET programmers that compiles down into simple, clean JavaScript that any browse

  12. Revealing the programming process

    DEFF Research Database (Denmark)

    Bennedsen, Jens; Caspersen, Michael Edelgaard

    2005-01-01

    One of the most important goals of an introductory programming course is that the students learn a systematic approach to the development of computer programs. Revealing the programming process is an important part of this; however, textbooks do not address the issue -- probably because...... the textbook medium is static and therefore ill-suited to expose the process of programming. We have found that process recordings in the form of captured narrated programming sessions are a simple, cheap, and efficient way of providing the revelation.We identify seven different elements of the programming...

  13. Android Emotions Revealed

    DEFF Research Database (Denmark)

    Vlachos, Evgenios; Schärfe, Henrik

    2012-01-01

    This work presents a method for designing facial interfaces for sociable android robots with respect to the fundamental rules of human affect expression. Extending the work of Paul Ekman towards a robotic direction, we follow the judgment-based approach for evaluating facial expressions to test...... in which case an android robot like the Geminoid|DK –a duplicate of an Original person- reveals emotions convincingly; when following an empirical perspective, or when following a theoretical one. The methodology includes the processes of acquiring the empirical data, and gathering feedback on them. Our...... findings are based on the results derived from a number of judgments, and suggest that before programming the facial expressions of a Geminoid, the Original should pass through the proposed procedure. According to our recommendations, the facial expressions of an android should be tested by judges, even...

  14. Chemistry of plutonium revealed

    International Nuclear Information System (INIS)

    Connick, R.E.

    1992-01-01

    In 1941 one goal of the Manhattan Project was to unravel the chemistry of the synthetic element plutonium as rapidly as possible. In this paper the work carried out at Berkeley from the spring of 1942 to the summer of 1945 is described briefly. The aqueous chemistry of plutonium is quite remarkable. Important insights were obtained from tracer experiments, but the full complexity was not revealed until macroscopic amounts (milligrams) became available. Because processes for separation from fission products were based on aqueous solutions, such solution chemistry was emphasized, particularly precipitation and oxidation-reduction behavior. The latter turned out to be unusually intricate when it was discovered that two more oxidation states existed in aqueous solution than had previously been suspected. Further, an equilibrium was rapidly established among the four aqueous oxidation states, while at the same time any three were not in equilibrium. These and other observations made while doing a crash study of a previously unknown element are reported

  15. In vivo measurement of cytosolic and mitochondrial pH using a pH-sensitive GFP derivative in Saccharomyces cerevisiae reveals a relation between intracellular pH and growth

    NARCIS (Netherlands)

    Orij, R.; Postmus, J.; ter Beek, A.; Brul, S.; Smits, G.J.

    2009-01-01

    The specific pH values of cellular compartments affect virtually all biochemical processes, including enzyme activity, protein folding and redox state. Accurate, sensitive and compartment-specific measurements of intracellular pH (pHi) dynamics in living cells are therefore crucial to the

  16. Selling Myths Revealed

    OpenAIRE

    Hopkins, Tom

    2017-01-01

    The true measure of the success of any business is the bottom line—sales minus cost of sales. That’s about as bare-bones as you can get when looking at it. Managing the cost of sales is an analytical process. It’s pretty much black and white. Managing sales, however, is a different matter.

  17. Direct measurement of Bisphenol A (BPA), BPA glucuronide and BPA sulfate in a diverse and low-income population of pregnant women reveals high exposure, with potential implications for previous exposure estimates: a cross-sectional study

    OpenAIRE

    Gerona, Roy R.; Pan, Janet; Zota, Ami R.; Schwartz, Jackie M.; Friesen, Matthew; Taylor, Julia A.; Hunt, Patricia A.; Woodruff, Tracey J.

    2016-01-01

    Background Bisphenol A (BPA) is a ubiquitous, endocrine-disrupting environmental contaminant that increases risk of some adverse developmental effects. Thus, it is important to characterize BPA levels, metabolic fate and sources of exposure in pregnant women. Methods We used an improved liquid chromatography-tandem mass spectrometry (LC-MS/MS) analytic method to directly and simultaneously measure unconjugated BPA (uBPA), BPA glucuronide and BPA sulfate in the urine of a population of ethnica...

  18. REVEAL: Software Documentation and Platform Migration

    Science.gov (United States)

    Wilson, Michael A.; Veibell, Victoir T.; Freudinger, Lawrence C.

    2008-01-01

    The Research Environment for Vehicle Embedded Analysis on Linux (REVEAL) is reconfigurable data acquisition software designed for network-distributed test and measurement applications. In development since 2001, it has been successfully demonstrated in support of a number of actual missions within NASA s Suborbital Science Program. Improvements to software configuration control were needed to properly support both an ongoing transition to operational status and continued evolution of REVEAL capabilities. For this reason the project described in this report targets REVEAL software source documentation and deployment of the software on a small set of hardware platforms different from what is currently used in the baseline system implementation. This report specifically describes the actions taken over a ten week period by two undergraduate student interns and serves as a final report for that internship. The topics discussed include: the documentation of REVEAL source code; the migration of REVEAL to other platforms; and an end-to-end field test that successfully validates the efforts.

  19. Vulnerability Factors and Effectiveness of Disaster Mitigation Measures in the Bangladesh Coast

    Science.gov (United States)

    Hossain, Md. Nazir; Paul, Shitangsu Kumar

    2018-01-01

    The major objective of this paper is to identify the vulnerability factors and examine the effectiveness of disaster mitigation measures undertaken by individuals, government and non-government organisations to mitigate the impacts of cyclones in the Bangladesh coast experiencing from Cyclone Aila. The primary data were collected from two villages of southwestern coastal areas of Bangladesh using questionnaire survey and interviews of the key informants. The data were analysed using the descriptive and inferential statistics. This paper reveals that the disaster management measures have a significant role to lessen the impacts of the cyclonic event, especially in pre-disaster preparedness, cyclone warning message dissemination, evacuation and post-disaster rehabilitation. The households, who have access to shelter, find weather forecast regularly and adopted pre-disaster awareness measures are relatively less susceptible to hazard's impacts. The disaster management measures undertaken by individuals and GOs and NGOs help coastal people to save their lives and property from the negative impacts of cyclones. The analysis shows that the NGOs' role is more effective and efficient than the GOs in cyclone disaster management. This paper identifies distance to shelter, participation in disaster training, efficient warning, etc. as the influential factors of vulnerability cyclones. The analysis finds the households as less affected who have adopted disaster preparedness measures. However, this paper concludes that the effective and proper disaster management and mitigation measures are very crucial to shield the lives and properties of the Bangladeshi coastal people.

  20. [Polymyalgia rheumatica revealing a lung cancer].

    Science.gov (United States)

    Cocquempot, K; Defuentes, G; Duron-Martineau, S; Berets, O; Vaylet, F; Margery, J

    2013-01-01

    Polymyalgia rheumatica is an inflammatory condition belonging to the connective tissue diseases, which occurs quite frequently in the elderly. Previously, cases have been reported in association with malignant tumours, in a synchronous fashion or prior to the appearance of the cancer. In these cases, the polymyalgia rheumatica is considered to be a paraneoplastic syndrome. We report the cases of a 63-year-old woman and a 58-year-old man with severe proximal girdle pain associated to a high-level of systemic inflammatory markers and a diagnosis of polymyalgia rheumatica was made. In the face of a lack of ineffectiveness of analgesic and anti-inflammatory treatments, an intensive investigation was undertaken which in both cases revealed an adenocarcinoma of the lung. The rheumatic manifestations responded well to chemotherapy targeting the lung tumour. We present here a review of the literature to give prominence to the diagnostic pitfalls that can occur around paraneoplastic polymyalgia rheumatica. The presence of therapeutic resistance at the onset of treatment and other atypical features may suggest the presence of an occult malignancy. Copyright © 2012 SPLF. Published by Elsevier Masson SAS. All rights reserved.

  1. Hydrologic Cycle Response to the Paleocene-Eocene Thermal Maximum at Austral, High-Latitude Site 690 as Revealed by In Situ Measurements of Foraminiferal Oxygen Isotope and Mg/Ca Ratios

    Science.gov (United States)

    Kozdon, R.; Kelly, D.; Fournelle, J.; Valley, J. W.

    2012-12-01

    published whole-shell δ18O records for this site; however, the mean baseline of the SIMS δ18O record is consistently ~1-2‰ lower than that of the published records. We attribute this δ18O offset to post-depositional diagenesis, which added 18O-enriched secondary calcite to planktic shells biasing conventional measurements. In the SIMS δ18O record, a minimum value of -4.4‰ is attained ~43 ka after the CIE onset. This δ18O minimum coincides with both the minimum δ13C value of the CIE and an abundance peak in warm-water immigrant taxa (morozovellids) of planktic foraminifera. Congruence of these two datasets reflects warming of sea-surface temperatures (SSTs), but the magnitude of the SST anomaly captured by complementary Mg/Ca data (~5°C) cannot account for the full magnitude of the δ18O decrease. This discrepancy is reconciled by lowering seawater δ18O to a value (-2‰) well below that computed for an ice-free world (-1.2‰). We therefore conclude that, much like in the Arctic, increased poleward moisture transport enhanced Antarctic continental runoff and reduced SSSs in the Weddell Sea region during the PETM.

  2. Continuous phosphorus measurements reveal catchment-scale transport processes

    NARCIS (Netherlands)

    Velde, Y. van der; Rozemeijer, J.C.

    2012-01-01

    A small fraction of the nutrients used for agriculture is transported by rivers and artificial drainage networks to downstream waters. In lakes and coastal seas such as the Baltic Sea and the Gulf of Mexico these nutrients cause large-scale algal blooms and hypoxia and thus are a major

  3. Partial radiogenic heat model for Earth revealed by geoneutrino measurements

    NARCIS (Netherlands)

    Abe, S.; et al., [Unknown; Decowski, M.P.

    2011-01-01

    The Earth has cooled since its formation, yet the decay of radiogenic isotopes, and in particular uranium, thorium and potassium, in the planet’s interior provides a continuing heat source. The current total heat flux from the Earth to space is 44.2±1.0 TW, but the relative contributions from

  4. REVEAL: Software Documentation and Platform Migration

    Science.gov (United States)

    Wilson, Michael A.; Veibell, Victoir T.

    2011-01-01

    The Research Environment for Vehicle Embedded Analysis on Linux (REVEAL) is reconfigurable data acquisition software designed for network-distributed test and measurement applications. In development since 2001, it has been successfully demonstrated in support of a number of actual missions within NASA's Suborbital Science Program. Improvements to software configuration control were needed to properly support both an ongoing transition to operational status and continued evolution of REVEAL capabilities. For this reason the project described in this report targets REVEAL software source documentation and deployment of the software on a small set of hardware platforms different from what is currently used in the baseline system implementation. This presentation specifically describes the actions taken over a ten week period by two undergraduate student interns and serves as an overview of the content of the final report for that internship.

  5. Reading strategies undertaken in posted comments on social networks

    Directory of Open Access Journals (Sweden)

    Sandra Carla Pereira Barbosa

    2017-06-01

    Full Text Available This article presents a study on the design from undelying reading and readers to the comments posted on social networks, Facebook and YouTube. The theory was based on: Kato (1985, Leffa (1996 and Kleiman (2013, when dealing with reading strategies, as well as the design of contemporany reading proposal by Coracini (2005.--- DOI: http://dx.doi.org/10.22409/cadletrasuff.2017n54a365

  6. Total hip replacement for Mseleni Joint Disease undertaken in a ...

    African Journals Online (AJOL)

    The objective of this project was to ascertain whether it is reasonable to perform specialist surgery for Mseleni Joint Disease (MJD) in a rural hospital by assessing the medium-term outcome of surgery for MJD performed at Mseleni. The study was designed as a review of patients at Mseleni Hospital in rural KwaZulu Natal, ...

  7. Since the beginning of the century, the country has undertaken ...

    African Journals Online (AJOL)

    Peninah

    Today, fish farming represents the fastest growing sector of food production. Moreover, aquaculture has a major role to play in the achievement of the first three Sustainable .... economic viability of shrimp farming in the coastal zone. .... although standards have been set for feed production and certification, enforcement has.

  8. Several qualitative acoustic surveys are undertaken each year in ...

    African Journals Online (AJOL)

    denise

    each year in Namibian waters to assess the biomass of the major pelagic fish ... VARIABLE SPATIAL STRUCTURE OF SCHOOLING PELAGIC FISH OFF. NAMIBIA: IMPLICATIONS ... (77%) and round herring (90%) between surveys, whereas biomass estimates of horse mackerel were relatively similar between surveys.

  9. Several qualitative acoustic surveys are undertaken each year in ...

    African Journals Online (AJOL)

    denise

    The aim of this paper is to quantify, by means of var- iograms, the spatial structure of aggregations of pelagic fish off Namibia, and to investigate their different strategies of space occupation. The influence of high- density areas on overall estimates of abundance and associated variance is also assessed, as is the effect of.

  10. Revealing the Economic Consequences of Group Cohesion

    OpenAIRE

    Gächter, Simon; Starmer, Chris; Tufano, Fabio

    2017-01-01

    We introduce the concept of "group cohesion" to capture the economic consequences of ubiquitous social relationships in group production. We measure group cohesion, adapting the "oneness scale" from psychology. A comprehensive program of new experiments reveals the considerable economic impact of cohesion: higher cohesion groups are significantly more likely to achieve Pareto-superior outcomes in classic weak-link coordination games. We show that effects of cohesion are economically large, ro...

  11. Measures of Cultural Competence in Nurses: An Integrative Review

    Directory of Open Access Journals (Sweden)

    Collette Loftin

    2013-01-01

    Full Text Available Background. There is limited literature available identifying and describing the instruments that measure cultural competence in nursing students and nursing professionals. Design. An integrative review was undertaken to identify the characteristics common to these instruments, examine their psychometric properties, and identify the concepts these instruments are designed to measure. Method. There were eleven instruments identified that measure cultural competence in nursing. Of these eleven instruments, four had been thoroughly tested in either initial development or in subsequent testing, with developers providing extensive details of the testing. Results. The current literature identifies that the instruments to assess cultural competence in nurses and nursing students are self-administered and based on individuals' perceptions. The instruments are commonly utilized to test the effectiveness of educational programs designed to increase cultural competence. Conclusions. The reviewed instruments measure nurses’ self-perceptions or self-reported level of cultural competence but offer no objective measure of culturally competent care from a patient’s perspective which can be problematic. Comparison of instruments reveals that they are based on a variety of conceptual frameworks and that multiple factors should be considered when deciding which instrument to use.

  12. Measures of Cultural Competence in Nurses: An Integrative Review

    Science.gov (United States)

    2013-01-01

    Background. There is limited literature available identifying and describing the instruments that measure cultural competence in nursing students and nursing professionals. Design. An integrative review was undertaken to identify the characteristics common to these instruments, examine their psychometric properties, and identify the concepts these instruments are designed to measure. Method. There were eleven instruments identified that measure cultural competence in nursing. Of these eleven instruments, four had been thoroughly tested in either initial development or in subsequent testing, with developers providing extensive details of the testing. Results. The current literature identifies that the instruments to assess cultural competence in nurses and nursing students are self-administered and based on individuals' perceptions. The instruments are commonly utilized to test the effectiveness of educational programs designed to increase cultural competence. Conclusions. The reviewed instruments measure nurses' self-perceptions or self-reported level of cultural competence but offer no objective measure of culturally competent care from a patient's perspective which can be problematic. Comparison of instruments reveals that they are based on a variety of conceptual frameworks and that multiple factors should be considered when deciding which instrument to use. PMID:23818818

  13. Cognitive Styles, Dynamic Geometry and Measurement Performance

    Science.gov (United States)

    Pitta-Pantazi, Demetra; Christou, Constantinos

    2009-01-01

    This paper reports the outcomes of an empirical study undertaken to investigate the effect of students' cognitive styles on achievement in measurement tasks in a dynamic geometry learning environment, and to explore the ability of dynamic geometry learning in accommodating different cognitive styles and enhancing students' learning. A total of 49…

  14. Decision Making and Revealed Preference

    DEFF Research Database (Denmark)

    de la Rosa, Leonidas Enrique

    If our decision-making processes are to some extent shaped by evolutionary pressures and our environment is different from that to which we adapted, some of our choices will not be in our best interest. But revealed preference is the only tool that we have so far to conduct a normative analysis...

  15. Revealing and Concealing in Antiquity

    DEFF Research Database (Denmark)

    Secrecy and the act of concealing and revealing knowledge effectually segregate the initiated and the uninitiated. The act of sharing or hiding knowledge plays a central role in all human relations private or public, political or religious. This volume explores the concept of secrecy and its...

  16. Revealed preference with limited consideration

    NARCIS (Netherlands)

    Demuynck, T.; Seel, C.

    2014-01-01

    We derive revealed preference tests for models where individuals use consideration sets to simplify their consumption problem. Our basic test provides necessary and sufficient conditions for consistency of observed choices with the existence of consideration set restrictions. The same conditions can

  17. Hyposplenism revealed by Plasmodium malariae infection.

    Science.gov (United States)

    Hommel, Benjamin; Galloula, Alexandre; Simon, Anne; Buffet, Pierre

    2013-08-02

    Hyposplenism, due to splenectomy, inherited red blood cell disorders or acquired conditions such as celiac disease, has an important impact on the severity of malaria, especially in non-immune patients. Conversely, that malaria may reveal functional hyposplenism has not been described previously. A 31-year old gardener was diagnosed with an uncomplicated attack of Plasmodium malariae 11 years after leaving the endemic area. In addition to trophozoites and schizonts, thick and thin smears also showed Howell-Jolly bodies, pointing to functional hyposplenism. This was later confirmed by the presence of a calcified spleen in the context of S/β + sickle-cell syndrome in a patient previously unaware of this condition. Malaria may reveal hyposplenism. Although Howell-Jolly bodies are morphologically similar to nuclei of young Plasmodium trophozoite, distinction on smears is based on the absence of cytoplasm and irregular size of Howell-Jolly bodies. In the patient reported here, hyposplenism was revealed by the occurrence of P. malariae infection relatively late in life. Timely diagnosis of hyposplenism resulted in the implementation of appropriate measures to prevent overwhelming infection with capsulated bacteria. This observation highlights the importance of diagnosing hyposplenism in patients with malaria despite the morphological similarities between ring nuclei and Howell-Jolly bodies on thick smears.

  18. Back-trajectory modeling of high time-resolution air measurement data to separate nearby sources

    Science.gov (United States)

    Strategies to isolate air pollution contributions from sources is of interest as voluntary or regulatory measures are undertaken to reduce air pollution. When different sources are located in close proximity to one another and have similar emissions, separating source emissions ...

  19. Activity measurement of phosphorus-32 in the presence of pure beta-emitting impurities

    CSIR Research Space (South Africa)

    Simpson, B

    2006-02-27

    Full Text Available Activity measurements undertaken at the CSIR's National Metrology Laboratory (NML) on a solution of the pure beta-emitting radionuclide phosphorus-32, which formed part of an international key comparison, are described. Since exploratory source...

  20. Transparency masters for mathematics revealed

    CERN Document Server

    Berman, Elizabeth

    1980-01-01

    Transparency Masters for Mathematics Revealed focuses on master diagrams that can be used for transparencies for an overhead projector or duplicator masters for worksheets. The book offers information on a compilation of master diagrams prepared by John R. Stafford, Jr., audiovisual supervisor at the University of Missouri at Kansas City. Some of the transparencies are designed to be shown horizontally. The initial three masters are number lines and grids that can be used in a mathematics course, while the others are adaptations of text figures which are slightly altered in some instances. The

  1. To Reveal Thy Heart Perchance to Reveal the World

    Directory of Open Access Journals (Sweden)

    Robert B. Faux

    2005-05-01

    Full Text Available Ronald PELIAS, a professor of speech communications, employs a variety of writing methods as examples of alternative ways to do research and to share with the reader a seldom seen and seldom considered aspect of academic life: Heart. In the early chapters of the book, PELIAS sets out to establish a way to place his Heart in the foreground; baring his emotional vulnerability, his humanness, his being in the world. Later chapters of the book encompass an autoethnographic study of academic life in which the previously revealed Heart is placed in context. In this review essay I discuss PELIAS' book in relation to the larger literature on autoethnography and subjectivist research; I follow this by discussing the need for and usefulness of such alternative methods using PELIAS' autoethnography of academic life as a context. URN: urn:nbn:de:0114-fqs050279

  2. In vivo measurements of cerebral metabolic abnormalities by proton spectroscopy after a transient ischemic attack revealing an internal carotid stenosis > 70%; Anomalies metaboliques cerebrales mesurees in vivo par la spectroscopie du proton dans les accidents ischemiques transitoires revelant une stenose de la carotide interne superieure a 70%

    Energy Technology Data Exchange (ETDEWEB)

    Giroud, M.; Becker, F.; Lemesle, M.; Walker, P.; Guy, F.; Martin, D.; Baudouin, N.; Brunotte, F.; Dumas, R. [Centre Hospitalier Universitaire, 21 -Dijon (France)

    1996-06-01

    Aims: The aim of this work is to look for cerebral metabolic abnormalities within the first 3 days after a transient ischemic attack revealing an internal carotid stenosis > 70 %. Methods: Five patients with a transient ischemic attack lasting between 30 and 180 minutes, affecting sensory and motor brachio-facial territory, with or without aphasia. Were studied. A CT-scan, an EEG, a cervical Doppler ultrasound, a standard arteriography, a magnetic resonance imaging and a proton spectroscopy were performed within the cerebral area affected by the transient ischemic attack. We measured 2 markers: N-acetyl-aspartate, the marker of the neuronal mass, and lactate, the marker of anaerobe metabolism. In each case, a contralateral internal stenosis was diagnosed by cervical Doppler ultrasound and standard arteriography. No cerebral infarction was observed. Results: With the affected cerebral area defined according to clinical and EEG features, proton spectroscopy showed a significant rise of lactate, without any change in N-acetyl-aspartate levels. Conclusions: Within the first 3 days after a transient ischemic attack, there is a significant risk of lactate inside the affected cerebral area. This change may reflect a localized and transient hypoperfusion, but long enough to induce a rise of lactate but not sufficient to produce a cerebral infarct. This area is probably at risk to induce cerebral infarct. This data lead us to study the metabolic change induced by the asymptomatic internal carotid stenosis. (authors). 18 refs.

  3. Plan competitions reveal entrepreneurial talent

    Energy Technology Data Exchange (ETDEWEB)

    Madison, Alison L.

    2011-05-15

    Monthly economic diversity column for Tri-City Herald business section. Excerpt below: There’s something to be said for gaining valuable real-world experience in a structured, nurturing environment. Take for instance learning to scuba dive in the comfort of my resort pool rather than immediately hanging out with sharks while I figure out little things like oxygen tanks and avoiding underwater panic attacks. Likewise, graduate students are getting some excellent, supportive real-world training through university business plan competitions. These competitions are places where smart minds, new technologies, months of preparation and coaching, and some healthy pre-presentation jitters collide to reveal not only solid new business ideas, but also some promising entrepreneurial talent. In fact, professionals from around our region descend upon college campuses every spring to judge these events, which help to bridge the gap between academics and the real technology and business-driven economy.

  4. Communication Games Reveal Preparation Contextuality

    Science.gov (United States)

    Hameedi, Alley; Tavakoli, Armin; Marques, Breno; Bourennane, Mohamed

    2017-12-01

    A communication game consists of distributed parties attempting to jointly complete a task with restricted communication. Such games are useful tools for studying limitations of physical theories. A theory exhibits preparation contextuality whenever its predictions cannot be explained by a preparation noncontextual model. Here, we show that communication games performed in operational theories reveal the preparation contextuality of that theory. For statistics obtained in a particular family of communication games, we show a direct correspondence with correlations in spacelike separated events obeying the no-signaling principle. Using this, we prove that all mixed quantum states of any finite dimension are preparation contextual. We report on an experimental realization of a communication game involving three-level quantum systems from which we observe a strong violation of the constraints of preparation noncontextuality.

  5. Communication Games Reveal Preparation Contextuality.

    Science.gov (United States)

    Hameedi, Alley; Tavakoli, Armin; Marques, Breno; Bourennane, Mohamed

    2017-12-01

    A communication game consists of distributed parties attempting to jointly complete a task with restricted communication. Such games are useful tools for studying limitations of physical theories. A theory exhibits preparation contextuality whenever its predictions cannot be explained by a preparation noncontextual model. Here, we show that communication games performed in operational theories reveal the preparation contextuality of that theory. For statistics obtained in a particular family of communication games, we show a direct correspondence with correlations in spacelike separated events obeying the no-signaling principle. Using this, we prove that all mixed quantum states of any finite dimension are preparation contextual. We report on an experimental realization of a communication game involving three-level quantum systems from which we observe a strong violation of the constraints of preparation noncontextuality.

  6. The chemistry of plutonium revealed

    International Nuclear Information System (INIS)

    Connick, R.E.

    1990-01-01

    In 1941 one goal of the Manhattan Project was to unravel the chemistry of the synthetic element plutonium as rapidly as possible. Important insights were obtained from tracer experiments, but the full complexity of plutonium chemistry was not revealed until macroscopic amounts (milligrams) became available. Because processes for separation from fission products were aqueous solution based, such solution chemistry was emphasized, particularly precipitation and oxidation-reduction behavior. The latter turned out to be unusually intricate when it was discovered that two more oxidation states existed in aqueous solution than had previously been suspected. Further, it was found that an equilibrium was rapidly established among the four aqueous oxidation states while at the same time any three were not in equilibrium. These and other observations made while doing a crash study of a previously unknown element will be reported

  7. Revealing ontological commitments by magic.

    Science.gov (United States)

    Griffiths, Thomas L

    2015-03-01

    Considering the appeal of different magical transformations exposes some systematic asymmetries. For example, it is more interesting to transform a vase into a rose than a rose into a vase. An experiment in which people judged how interesting they found different magic tricks showed that these asymmetries reflect the direction a transformation moves in an ontological hierarchy: transformations in the direction of animacy and intelligence are favored over the opposite. A second and third experiment demonstrated that judgments of the plausibility of machines that perform the same transformations do not show the same asymmetries, but judgments of the interestingness of such machines do. A formal argument relates this sense of interestingness to evidence for an alternative to our current physical theory, with magic tricks being a particularly pure source of such evidence. These results suggest that people's intuitions about magic tricks can reveal the ontological commitments that underlie human cognition. Copyright © 2014 Elsevier B.V. All rights reserved.

  8. Frequency swept fibre laser for wind speed measurements

    DEFF Research Database (Denmark)

    Pedersen, Anders Tegtmeier

    undertaken with a positive outcome encouraging an experimental trial to measure wind with a such construction. Therefore, a small telescope CW lidar designed for turbine blade integration has been tested in a high performance wind tunnel, and very good agreement with reference measurements has been obtained....

  9. Systematic hardness measurements on some rare earth garnet ...

    Indian Academy of Sciences (India)

    Unknown

    Microhardness measurements were undertaken on twelve rare earth garnet crystals. In yttrium aluminium garnet and gadolinium ... syan (1997) has quoted a single value for Gd3Sc2Ga3O12. In the present study measurements have ... small and within the limits of experimental error. There- fore, where pure garnet crystals ...

  10. Measures for Measures

    DEFF Research Database (Denmark)

    Jørgensen, Sune Lehman; A.D., Jackson; Lautrup, B.E.

    2006-01-01

    Are some ways of measuring scientific quality better than others? Sune Lehmann, Andrew D. Jackson and Benny E. Lautrup analyse the reliability of commonly used methods for comparing citation records.......Are some ways of measuring scientific quality better than others? Sune Lehmann, Andrew D. Jackson and Benny E. Lautrup analyse the reliability of commonly used methods for comparing citation records....

  11. Hubble Images Reveal Jupiter's Auroras

    Science.gov (United States)

    1996-01-01

    These images, taken by the Hubble Space Telescope, reveal changes in Jupiter's auroral emissions and how small auroral spots just outside the emission rings are linked to the planet's volcanic moon, Io. The images represent the most sensitive and sharply-detailed views ever taken of Jovian auroras.The top panel pinpoints the effects of emissions from Io, which is about the size of Earth's moon. The black-and-white image on the left, taken in visible light, shows how Io and Jupiter are linked by an invisible electrical current of charged particles called a 'flux tube.' The particles - ejected from Io (the bright spot on Jupiter's right) by volcanic eruptions - flow along Jupiter's magnetic field lines, which thread through Io, to the planet's north and south magnetic poles. This image also shows the belts of clouds surrounding Jupiter as well as the Great Red Spot.The black-and-white image on the right, taken in ultraviolet light about 15 minutes later, shows Jupiter's auroral emissions at the north and south poles. Just outside these emissions are the auroral spots. Called 'footprints,' the spots are created when the particles in Io's 'flux tube' reach Jupiter's upper atmosphere and interact with hydrogen gas, making it fluoresce. In this image, Io is not observable because it is faint in the ultraviolet.The two ultraviolet images at the bottom of the picture show how the auroral emissions change in brightness and structure as Jupiter rotates. These false-color images also reveal how the magnetic field is offset from Jupiter's spin axis by 10 to 15 degrees. In the right image, the north auroral emission is rising over the left limb; the south auroral oval is beginning to set. The image on the left, obtained on a different date, shows a full view of the north aurora, with a strong emission inside the main auroral oval.The images were taken by the telescope's Wide Field and Planetary Camera 2 between May 1994 and September 1995.This image and other images and data

  12. Estudios previos cursados y género de los maestros de primaria en formación: efectos sobre la resolución de problemas / Pre-service primary teachers' gender and studies previously undertaken: effects on problem solving

    Directory of Open Access Journals (Sweden)

    Alexandre Caballer Alonso

    2014-10-01

    Full Text Available Resumen: Este trabajo analiza la influencia del género y los estudios previos cursados en la resolución de problemas. Se utilizó un diseño experimental con dos variables independientes (género y estudios previos y una variable dependiente (puntuación en los problemas. Se administró un cuadernillo con dos problemas de diferente estructura a 66 estudiantes de tercer curso del Grado de Maestro en Educacion Primaria de la misma Facultad (Facultad de Magisterio de la Universidad de Valencia, España. Los resultados de los análisis de varianza simple muestran que: a los estudiantes de sexo masculino resuelven el problema difícil con más éxito que las estudiantes, b los estudiantes que han cursado bachillerato no resuelven los problemas significativamente mejor que los que no lo han cursado y, c los estudiantes que siguieron un itinerario en 4º de la ESO con Física y Química resuelven significativamente mejor los problemas que los restantes. Abstract: This study analyses the influence of gender and studies previously undertaken on problem-solving. An experimental design was used with two independent variables (gender and studies previously undertaken and one dependent variable (scores in the problems. A booklet containing two word problems that differ from each other in structure was administered to 66 third-year pre-service primary teachers from the same Faculty (Faculty of Teacher Training, University of Valencia, Spain. The results of the analyses of variance simple showed that: a men undergraduate students solve the difficult problem more successfully than women undergraduate students, b students who had completed post-compulsory secondary education do not solve the problems significantly better than the others, and c students who had studied physics and chemistry in the tenth grade at high school solve the problems significantly better than the others.

  13. LDA measurements in the Francis-99 draft tube cone

    International Nuclear Information System (INIS)

    Sundstrom, L R J; Amiri, K; Cervantes, M J; Bergan, C; Dahlhaug, O G

    2014-01-01

    Velocity measurements were performed in the draft tube cone of a 1:5.1 scaled model of the Tokke hydropower plant, Norway; also known as the Francis-99 model. Results from the laser Doppler anemometry measurements undertaken at three operating points will be used as validation data for an upcoming workshop on the state of the art of Francis turbine numerical simulation. With the turbine operating at the best efficiency point, a sensitivity analysis of the flow parameters head, flow rate and runner rotational speed shows that the effects on the dimensionless velocity profiles are small as long as n ED and Q ED are held constant. The results indicate a well-functioning turbine at the best efficiency point and high load. At the part load operating point, a vortex breakdown occurs which distorts the velocity profiles and significantly lowers the turbine's hydraulic efficiency. Frequency spectrums of each LDA signal at part load reveals a peak which is asynchronous to that of the runner angular speed. The peaks might be related to the precession of a rotating vortex rope but the characteristics of the LDA signals are different compared to previous studies involving rotating vortex ropes

  14. Saturn Probe: Revealing Solar System Origins

    Science.gov (United States)

    Spilker, T. R.

    2015-12-01

    Comparative studies of the gas giant and ice giant planets are needed to reliably discriminate among competing theories of the origin and evolution of giant planets and the solar system, but we lack critical measurements. A Saturn atmospheric entry probe mission would fill a vital part of that gap, allowing comparative studies of Jupiter and Saturn, providing the basis for later comparisons with the ice giants Uranus and Neptune, and informing studies of extrasolar planetary systems now being characterized. The Galileo Probe mission provided the first in situ studies of Jupiter's atmosphere. Similar measurements at Saturn, Uranus and Neptune would provide an important comparative planetology context for the Galileo results. Cassini's "Proximal Orbits" in 2017 will reveal Saturn's internal structure to complement the Juno mission's similar measurements at Jupiter. A Saturn entry probe, complementing the Galileo Probe investigations at Jupiter, would complete a solid basis for improved understanding of both Jupiter and Saturn, an important stepping stone to understanding Uranus and Neptune and solar system formation and evolution. The 2012 Decadal Survey ("DS") added Saturn Probe science objectives to NASA's New Frontiers Program: highest-priority Tier 1 objectives any New Frontiers implementation must achieve, and Tier 2, high priority but lower than Tier 1. A DS mission concept study using extremely conservative assumptions concluded that a Saturn Probe project could fit within New Frontiers resource constraints, giving a PI confidence that they could pursue some Tier 2 objectives, customizing for the proper balance of science return, science team composition, procured or contributed instruments, etc. Contributed instruments could significantly enhance the payload and the science team for greater science return. They also provide international collaboration opportunities, with science benefits well demonstrated by missions such as Cassini-Huygens and Rosetta.

  15. Measurement Engineering

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Jun Hui; Kim, Hyeong Cheol

    2001-08-15

    This book deals with conception of measurement such as measuring and test, instrument for measurement, and types and methods of measuring, general things for precision measurement like indicator, gauge standard and Abbe's principle, measuring instrument such as vernier calipers, micrometer calipers, each gage, an optical instrument, and 3D instrument, choice and using of measuring instrument on length measurement, angle measurement, and side measurement, application and calculation for measuring using trigonometrical function, sin law, and the Pythagorean Theorem.

  16. Puerto Rico Revealed Preference Survey Data 2004

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Revealed preference models provide insights into recreational angler behavior and the economic value of recreational fishing trips. Revealed preference data is...

  17. Hidden acoustic information revealed by intentional nonlinearity

    Science.gov (United States)

    Dowling, David R.

    2017-11-01

    Acoustic waves are omnipresent in modern life and are well described by the linearized equations of fluid dynamics. Once generated, acoustic waves carry and collect information about their source and the environment through which they propagate, respectively, and this information may be retrieved by analyzing recordings of these waves. Because of this, acoustics is the primary means for observation, surveillance, reconnaissance, and remote sensing in otherwise opaque environments, such as the Earth's oceans and crust, and the interior of the human body. For such information-retrieval tasks, acoustic fields are nearly always interrogated within their recorded frequency range or bandwidth. However, this frequency-range restriction is not general; acoustic fields may also carry (hidden) information at frequencies outside their bandwidth. Although such a claim may seem counter intuitive, hidden acoustic-field information can be revealed by re-introducing a marquee trait of fluid dynamics: nonlinearity. In particular, an intentional quadratic nonlinearity - a form of intra-signal heterodyning - can be used to obtain acoustic field information at frequencies outside a recorded acoustic field's bandwidth. This quadratic nonlinearity enables a variety of acoustic remote sensing applications that were long thought to be impossible. In particular, it allows the detrimental effects of sparse recordings and random scattering to be suppressed when the original acoustic field has sufficient bandwidth. In this presentation, the topic is developed heuristically, with a just brief exposition of the relevant mathematics. Hidden acoustic field information is then revealed from simulated and measured acoustic fields in simple and complicated acoustic environments involving frequencies from a few Hertz to more than 100 kHz, and propagation distances from tens of centimeters to hundreds of kilometers. Sponsored by ONR, NAVSEA, and NSF.

  18. Comfort measures: a concept analysis.

    Science.gov (United States)

    Oliveira, Irene

    2013-01-01

    Reference to the concept of comfort measures is growing in the nursing and medical literature; however, the concept of comfort measures is rarely defined. For the comfort work of nurses to be recognized, nurses must be able to identify and delineate the key attributes of comfort measures. A concept analysis using Rodgers' evolutionary method (2000) was undertaken with the goal of identifying the core attributes of comfort measures and thereby clarifying this concept. Health care literature was accessed from the CINAHL and PubMed databases. No restrictions were placed on publication dates. Four main themes of attributes for comfort measures were identified during the analysis. Comfort measures involve an active, strategic process including elements of "stepping in" and "stepping back," are both simple and complex, move from a physical to a holistic perspective and are a part of supportive care. The antecedents to comfort measures are comfort needs and the most common consequence of comfort measures is enhanced comfort. Although the concept of comfort measures is often associated with end-of-life care, this analysis suggests that comfort measures are appropriate for nursing care in all settings and should be increasingly considered in the clinical management of patients who are living with multiple, chronic comorbidities.

  19. Measure for measure

    Science.gov (United States)

    Weinberger, Peter

    2012-06-01

    The present system of measures for length, weight and capacity (volume) originates from scientific ideas expressed during the French Revolution in 1789. The history of a compatible unit of length, however, turns out to be less of a scientific but rather of a political character. Here reports to the Philosophical Magazine made in the first quarter of the nineteenth century are used to trace the cultural split between meters and inches, and between kilograms and pounds, that can be experienced in many parts of the world.

  20. Occupational hazards and safety measures among stone quarry ...

    African Journals Online (AJOL)

    The health conditions of workers all over the world vary widely, depending among others on the geographical location, the type of employment and the patterns of work. The study was undertaken to determine the occupational hazards, and safety measures among Stone quarry workers in Zaria, Northern Nigeria. It involved ...

  1. An Instrument for the Measurement of Parental Authority Prototypes.

    Science.gov (United States)

    Buri, John R.

    Baumrind (1971) proposed three distinct patterns of parental authority (permissiveness, authoritarianism, and authoritativeness) and measured these parenting styles through interviews with parents and their children and through observations of parents interacting with their children. This study was undertaken to develop a readily-accessible,…

  2. Revealing household characteristics from smart meter data

    International Nuclear Information System (INIS)

    Beckel, Christian; Sadamori, Leyna; Staake, Thorsten; Santini, Silvia

    2014-01-01

    Utilities are currently deploying smart electricity meters in millions of households worldwide to collect fine-grained electricity consumption data. We present an approach to automatically analyzing this data to enable personalized and scalable energy efficiency programs for private households. In particular, we develop and evaluate a system that uses supervised machine learning techniques to automatically estimate specific “characteristics” of a household from its electricity consumption. The characteristics are related to a household's socio-economic status, its dwelling, or its appliance stock. We evaluate our approach by analyzing smart meter data collected from 4232 households in Ireland at a 30-min granularity over a period of 1.5 years. Our analysis shows that revealing characteristics from smart meter data is feasible, as our method achieves an accuracy of more than 70% over all households for many of the characteristics and even exceeds 80% for some of the characteristics. The findings are applicable to all smart metering systems without making changes to the measurement infrastructure. The inferred knowledge paves the way for targeted energy efficiency programs and other services that benefit from improved customer insights. On the basis of these promising results, the paper discusses the potential for utilities as well as policy and privacy implications. - Highlights: • Many household characteristics can be automatically inferred from smart meter data. • We develop a system to infer employment status and number of occupants, for instance. • We evaluate our system analyzing data collected from 4232 households in Ireland. • The insights enable personalized and scalable efficiency campaigns for utilities. • Energy efficiency measures must be complemented by privacy protection

  3. The Use of Helmholtz Resonance for Measuring the Volume of Liquids and Solids

    Directory of Open Access Journals (Sweden)

    Clive E. Davies

    2010-11-01

    Full Text Available An experimental investigation was undertaken to ascertain the potential of using Helmholtz resonance for volume determination and the factors that may influence accuracy. The uses for a rapid non-interference volume measurement system range from agricultural produce and mineral sampling through to liquid fill measurements. By weighing the sample the density can also measured indirectly.

  4. Revealing the interface in polymer nanocomposites.

    Science.gov (United States)

    Zammarano, Mauro; Maupin, Paul H; Sung, Li-Piin; Gilman, Jeffrey W; McCarthy, Edward D; Kim, Yeon S; Fox, Douglas M

    2011-04-26

    The morphological characterization of polymer nanocomposites over multiple length scales is a fundamental challenge. Here, we report a technique for high-throughput monitoring of interface and dispersion in polymer nanocomposites based on Förster resonance energy transfer (FRET). Nanofibrillated cellulose (NFC), fluorescently labeled with 5-(4,6-dichlorotriazinyl)-aminofluorescein (FL) and dispersed into polyethylene (PE) doped with Coumarin 30 (C30), is used as a model system to assess the ability of FRET to evaluate the effect of processing on NFC dispersion in PE. The level of energy transfer and its standard deviation, measured by fluorescence spectroscopy and laser scanning confocal microscopy (LSCM), are exploited to monitor the extent of interface formation and composite homogeneity, respectively. FRET algorithms are used to generate color-coded images for a real-space observation of energy transfer efficiency. These images reveal interface formation at a nanoscale while probing a macroscale area that is large enough to be representative of the entire sample. The unique ability of this technique to simultaneously provide orientation/spatial information at a macroscale and nanoscale features, encoded in the FRET signal, provides a new powerful tool for structure-property-processing investigation in polymer nanocomposites.

  5. Fetal anatomy revealed with fast MR sequences.

    Science.gov (United States)

    Levine, D; Hatabu, H; Gaa, J; Atkinson, M W; Edelman, R R

    1996-10-01

    Although all the imaging studies in this pictorial essay were done for maternal rather than fetal indications, fetal anatomy was well visualized. However, when scans are undertaken for fetal indications, fetal motion in between scout views and imaging sequences may make specific image planes difficult to obtain. Of the different techniques described in this review, we preferred the HASTE technique and use it almost exclusively for scanning pregnant patients. The T2-weighting is ideal for delineating fetal organs. Also, the HASTE technique allows images to be obtained in 430 msec, limiting artifacts arising from maternal and fetal motion. MR imaging should play a more important role in evaluating equivocal sonographic cases as fast scanning techniques are more widely used. Obstetric MR imaging no longer will be limited by fetal motion artifacts. When complex anatomy requires definition in a complicated pregnant patient, MR imaging should be considered as a useful adjunct to sonography.

  6. The 'revealed preferences' theory: Assumptions and conjectures

    International Nuclear Information System (INIS)

    Green, C.H.

    1983-01-01

    Being kind of intuitive psychology the 'Revealed-Preferences'- theory based approaches towards determining the acceptable risks are a useful method for the generation of hypotheses. In view of the fact that reliability engineering develops faster than methods for the determination of reliability aims the Revealed-Preferences approach is a necessary preliminary help. Some of the assumptions on which the 'Revealed-Preferences' theory is based will be identified and analysed and afterwards compared with experimentally obtained results. (orig./DG) [de

  7. Psychometric properties of carer-reported outcome measures in palliative care: A systematic review

    Science.gov (United States)

    Michels, Charlotte TJ; Boulton, Mary; Adams, Astrid; Wee, Bee; Peters, Michele

    2016-01-01

    Background: Informal carers face many challenges in caring for patients with palliative care needs. Selecting suitable valid and reliable outcome measures to determine the impact of caring and carers’ outcomes is a common problem. Aim: To identify outcome measures used for informal carers looking after patients with palliative care needs, and to evaluate the measures’ psychometric properties. Design: A systematic review was conducted. The studies identified were evaluated by independent reviewers (C.T.J.M., M.B., M.P.). Data regarding study characteristics and psychometric properties of the measures were extracted and evaluated. Good psychometric properties indicate a high-quality measure. Data sources: The search was conducted, unrestricted to publication year, in the following electronic databases: Applied Social Sciences Index and Abstracts, Cumulative Index to Nursing and Allied Health Literature, The Cochrane Library, EMBASE, PubMed, PsycINFO, Social Sciences Citation Index and Sociological Abstracts. Results: Our systematic search revealed 4505 potential relevant studies, of which 112 studies met the inclusion criteria using 38 carer measures for informal carers of patients with palliative care needs. Psychometric properties were reported in only 46% (n = 52) of the studies, in relation to 24 measures. Where psychometric data were reported, the focus was mainly on internal consistency (n = 45, 87%), construct validity (n = 27, 52%) and/or reliability (n = 14, 27%). Of these, 24 measures, only four (17%) had been formally validated in informal carers in palliative care. Conclusion: A broad range of outcome measures have been used for informal carers of patients with palliative care needs. Little formal psychometric testing has been undertaken. Furthermore, development and refinement of measures in this field is required. PMID:26407683

  8. Measuring the chargino parameters

    Indian Academy of Sciences (India)

    After the supersymmetric particles have been discovered, the priority will be to determine independently the fundamental parameters to reveal the structure of the underlying supersymmetric theory. In my talk I discuss how the chargino sector can be reconstructed completely by measuring the cross-sections with polarized ...

  9. Revealing Conceptual Understanding of International Business

    Science.gov (United States)

    Ashley, Sue; Schaap, Harmen; de Bruijn, Elly

    2017-01-01

    This study aims to identify an adequate approach for revealing conceptual understanding in higher professional education. Revealing students' conceptual understanding is an important step towards developing effective curricula, assessment and aligned teaching strategies to enhance conceptual understanding in higher education. Essays and concept…

  10. The Quality of Canadian and U.S. Government Health Documents Remains Unchallenged Until Better Research Can Be Undertaken. A review of: Lambert, Frank. “Assessing the Authoritativeness of Canadian and American Health Documents: A Comparative Analysis Using Informetric Methodologies.” Government Information Quarterly 22.2 (2005: 277‐96.

    Directory of Open Access Journals (Sweden)

    Michael Corkett

    2006-12-01

    Full Text Available Objective ‐ To assess by means of citation analysis whether the public trust afforded health documents published by the Canadian and U.S. governments is appropriate, and to ascertain whether differences in the respective health care systems influence how publications are produced.Design – Comparative study.Setting – The Canadian Depository Service Program (DSP and the U.S. Department of Health and Human Services (DHHS websites.Subjects – One hundred sixty‐six electronic documents sourced from the DSP website, and 284 electronic documents sourced from the DHHS website.Methods – Subjects were randomly selected from repositories offering the most comprehensive collections. Documents with evidence of references to other works used in preparation were separated from thos ewithout such characteristics. Data variables were collected from documents with evidence of references. Statistical analysis of the data was undertaken.Main results – Of the respective samples, 89(53% from the DSP and 109 (38.4% from the DHHS contained references. Personal authors were identified in 46 (51.7% and 63(58% of the respective subsets. Handbooks and guidebooks accounted for the largest portion of the DSP subset (29; 32.6% and government periodicals were the largest constituent of the DHHS subset (41; 37.6%. Scholarly journals were the most common reference type for both the DSP (44% and the DHHS (58.5% subsets. The number of references per document was widely dispersed for both subsets; the DSP mean was approximately 64 (SD=114.68 and the DHHS was 73.71 (SD=168.85. Kruskal‐Wallis subset analysis of median number of references by document type found differences generalizable to the entire DSP (pConclusion – Significant differences in reference use frequencies between DSP and DHHS documents challenges Foskett’s stance that documents of value contain references (Foskett. Use of peer‐reviewed scholarly journals for both DSP and DHHS publications was

  11. The validity and reliability of 5-Hz global positioning system units to measure team sport movement demands.

    Science.gov (United States)

    Johnston, Richard J; Watsford, Mark L; Pine, Matthew J; Spurrs, Robert W; Murphy, Aron J; Pruyn, Elizabeth C

    2012-03-01

    The purpose of this research was to investigate the validity and the reliability of 5-Hz MinimaxX global positioning system (GPS) units measuring athlete movement demands. A team sport simulation circuit (files collected from each unit = 12) and flying 50-m sprints (files collected from each unit = 34) were undertaken, during which the total distance covered; peak speed; player load; the distance covered; time spent and number of efforts performed walking, jogging, running, high-speed running, and sprinting were examined. Movement demands were also separately categorized into low-intensity activity, high-intensity running, and very high-intensity running. The results revealed that GPS was a valid and reliable measure of total distance covered (p > 0.05, percentage typical error of measurement [%TEM] 0.05, %TEM 5-10%). Further, GPS was found to be a reliable measure of player load (%TEM 4.9%) and the distance covered, time spent, and number of efforts performed at certain velocity zones (%TEM 10%). The level of GPS error was found to increase along with the velocity of exercise. The findings demonstrated that GPS is capable of measuring movement demands performed at velocities GPS velocities >20 km·h(-1).

  12. Measuring return to work.

    Science.gov (United States)

    Wasiak, Radoslaw; Young, Amanda E; Roessler, Richard T; McPherson, Kathryn M; van Poppel, Mireille N M; Anema, Johannes R

    2007-12-01

    It is argued that one of the factors limiting the understanding of return to work (RTW) following work disability is the use of measurement tools that do not capture a complete picture of workers' RTW experiences. To facilitate the investigation of RTW, the current authors proposed a developmental conceptualization of RTW, which argues for an expanded awareness that encompasses four phases: off work, work reintegration, work maintenance and advancement. This paper reports on work undertaken with the aim of operationalizing the conceptualization. A review of the RTW and related literature, with databases searched including PubMed, EconLit, and PsycInfo. We began by extracting details of RTW instruments used by previous researchers. We then interpreted these within the context of the phases of RTW. Using the International Classification of Functioning, Disability, and Health (ICF) to inform our thinking and coding structure, we conceptualized phase-based RTW outcomes and categorized them as 'tasks and actions', 'contextual' or 'process driven'. Iteratively, we reviewed existing instruments for their use as measures of RTW. Where gaps in instrumentation were found, the wider vocational and career assessment literature was searched for instruments that could be adapted for use in RTW research. Results indicate that, although numerous research instruments have been used to assess RTW, within the scientific literature some important dimensions of RTW lack instrumentation. In particular, we found that outcomes such as goal setting, motivation, expectation, job seeking, work maintenance, and career advancement require operationalization. Amongst the outcomes had been operationalized, we found considerable variation in conceptual development and application. The lack of consistency and comprehensiveness of RTW measurement is one of the factors compromising the advancement of the field of RTW research. It is suggested that a more complete and psychometrically sound array of

  13. Measuring Socioeconomic Background in PISA: One Size Might Not Fit All

    Science.gov (United States)

    Rutkowski, David; Rutkowski, Leslie

    2013-01-01

    As part of its flagship educational study--the Programme for International Student Assessment (PISA)--the Organisation for Economic Co-operation and Development (OECD) has undertaken extensive work to create an internationally relevant composite indicator aimed at measuring socioeconomic background. However, the degree to which a single measure of…

  14. Final Report: Geothermal dual acoustic tool for measurement of rock stress

    Energy Technology Data Exchange (ETDEWEB)

    Normann, Randy A. [Perma Works LLC, Pattonville, TX (United States)

    2014-12-01

    This paper outlines the technology need for a rock formation stress measurement in future EGS wells. This paper reports on the results of work undertaken under a Phase I, DOE/SBIR on the feasibility to build an acoustic well logging tool for measuring rock formation stress.

  15. Final Report. Geothermal Dual Acoustic Tool for Measurement of Rock Stress

    Energy Technology Data Exchange (ETDEWEB)

    Normann, Randy A [Perma Works LLC, Pattonville, TX (United States)

    2014-12-01

    This paper outlines the technology need for a rock formation stress measurement in future EGS wells. This paper reports on the results of work undertaken under a Phase I, DOE/SBIR on the feasibility to build an acoustic well logging tool for measuring rock formation stress.

  16. Summary of QM02 Measurements

    International Nuclear Information System (INIS)

    Fisher, Andrew

    2010-01-01

    This note summarizes both the beam-based and various laboratory measurements of quadrupole magnets, units 387 and 428, used for QM02 in the LCLS Injector. These were undertaken because of a consistent discrepancy between accelerator model predictions and beam observations which seemed to indicate a weak QM02. A report 'QM02 Strength Measurement', by Welch and Wu, describes the discrepancy and beam-based measurements on unit 387. Subsequently, unit 387 was replaced by unit 428, refinements were made to analysis of the beam-based measurements were made, and additional magnetic measurements were made on unit 387 in the lab. These new results are summarized in this note. The principle results are: (1) Laboratory measurements of integrated gradient for the same magnet, or for different magnets of the same type, are all within 1% of each other at gradients of interest. These cases cover three independent types of measurements, disassembly/reassembly of the units, and extended periods of time between measurements. (2) Standardization, or lack thereof, can cause integrated gradient errors of approximately 0.2 kG, which can amount to a few percent of the strength of the magnet depending on the setting. (3) Model-independent beam-based measurements indicate the magnets are actually weaker than expected by about 2 percent, but these measurements are subject to the uncertainty of the BPMS1 location. (4) The standardization cycle is effective. (5) The stainless steel BPM vacuum chamber inside the magnets has no significant effect on the beam. The discrepancy between the accelerator model predictions and the actual orbit response is not resolved, but the evidence points away from magnetic strength errors as the source. Differences between the model locations and effective locations of BPM's is a possible culprit. This idea is explored in Section 2. Table 1 summarizes the measurement activities that were performed on the units. The dates listed correspond to the date when the

  17. Abrasive supply for ancient Egypt revealed

    International Nuclear Information System (INIS)

    Peltz, C.; Bichler, M.

    2008-01-01

    In the framework of the major research scheme 'Synchronization of Civilizations in the Eastern Mediterranean Region in the 2nd Millennium B.C' instrumental neutron activation analysis (INAA) was used to determine 30 elements in pumice from archaeological excavations to reveal their specific volcanic origin. In ancient time, the widespread pumiceous products of several eruptions in the Aegean region have been used as abrasive tools and were therefore popular trade objects. The correlation of such archaeological findings to a specific eruption of known age would therefore allow to certify a maximum age of the respective stratum ('dating by first appearance'). Pumices from the Aegean region can easily be distinguished by their trace element distribution patterns. This has been shown by previous studies of the group. The elements Al, Ba, Ca, Ce, Co, Cr, Cs, Dy, Eu, Fe, Hf, K, La, Lu, Mn, Na, Nd, Rb, Sb, Sc, Sm, Ta, Tb, Th, Ti, U, V, Yb, Zr and Zn were determined in 16 samples of pumice lumps from excavations in Tell-el-Dab'a and Tell-el-Herr (Egypt). Two irradiation cycles and five measurement runs were applied. To show the accuracy of the results obtained, typical samples of the most important pumice sources in the Aegean region, particularly from Milos, Nisyros, Kos and Thera were analyzed together with the Egyptian samples of unknown origin. A reliable identification of the samples is achieved by comparing these results to the database compiled in previous studies. The geographical positions of these islands are shown. Within the error range, most of the elements determined in typical representatives of Milos, Nisyros, Kos and Santorini were in perfect agreement with values from the literature. On the basis of the Cluster graphics presented, it is possible to relate unknown pumice to its primary source, just by comparing the relation of a few elements, like Ta-Eu and Th-Hf. One concludes that all samples except one can be related to the Minoan eruption of Thera

  18. Metabolomic Analyses of Leishmania Reveal Multiple Species Differences and Large Differences in Amino Acid Metabolism.

    Directory of Open Access Journals (Sweden)

    Gareth D Westrop

    Full Text Available Comparative genomic analyses of Leishmania species have revealed relatively minor heterogeneity amongst recognised housekeeping genes and yet the species cause distinct infections and pathogenesis in their mammalian hosts. To gain greater information on the biochemical variation between species, and insights into possible metabolic mechanisms underpinning visceral and cutaneous leishmaniasis, we have undertaken in this study a comparative analysis of the metabolomes of promastigotes of L. donovani, L. major and L. mexicana. The analysis revealed 64 metabolites with confirmed identity differing 3-fold or more between the cell extracts of species, with 161 putatively identified metabolites differing similarly. Analysis of the media from cultures revealed an at least 3-fold difference in use or excretion of 43 metabolites of confirmed identity and 87 putatively identified metabolites that differed to a similar extent. Strikingly large differences were detected in their extent of amino acid use and metabolism, especially for tryptophan, aspartate, arginine and proline. Major pathways of tryptophan and arginine catabolism were shown to be to indole-3-lactate and arginic acid, respectively, which were excreted. The data presented provide clear evidence on the value of global metabolomic analyses in detecting species-specific metabolic features, thus application of this technology should be a major contributor to gaining greater understanding of how pathogens are adapted to infecting their hosts.

  19. Measurement methods of building structures deflections

    Directory of Open Access Journals (Sweden)

    Wróblewska Magdalena

    2018-01-01

    Full Text Available Underground mining exploitation is leading to the occurrence of deformations manifested by, in particular, sloping terrain. The structures situated on the deforming subsoil are subject to uneven subsidence which is leading in consequence to their deflection. Before a building rectification process takes place by, e.g. uneven raising, the structure's deflection direction and value is determined so that the structure is restored to its vertical position as a result of the undertaken remedial measures. Deflection can be determined by applying classical as well as modern measurement techniques. The article presents examples of measurement methods used considering the measured elements of building structures’ constructions and field measurements. Moreover, for a given example of a mining area, the existing deflections of buildings were compared with mining terrain sloping.

  20. NASA Cold Land Processes Experiment (CLPX 2002/03): Field measurements of snowpack properties and soil moisture

    Science.gov (United States)

    Kelly Elder; Don Cline; Glen E. Liston; Richard Armstrong

    2009-01-01

    A field measurement program was undertaken as part NASA's Cold Land Processes Experiment (CLPX). Extensive snowpack and soil measurements were taken at field sites in Colorado over four study periods during the two study years (2002 and 2003). Measurements included snow depth, density, temperature, grain type and size, surface wetness, surface roughness, and...

  1. Measuring worker productivity: frameworks and measures.

    Science.gov (United States)

    Beaton, Dorcas; Bombardier, Claire; Escorpizo, Reuben; Zhang, Wei; Lacaille, Diane; Boonen, Annelies; Osborne, Richard H; Anis, Aslam H; Strand, C Vibeke; Tugwell, Peter S

    2009-09-01

    Worker productivity is a combination of time off work (absenteeism) due to an illness and time at work but with reduced levels of productivity while at work (also known as presenteeism). Both can be gathered with a focus on application as a cost indicator and/or as an outcome state for intervention studies. We review the OMERACT worker productivity groups' progress in evaluating measures of worker productivity for use in arthritis using the OMERACT filter. Attendees at OMERACT 9 strongly endorsed the importance of work as an outcome in arthritis. Consensus was reached (94% endorsement) for fielding a broader array of indicators of absenteeism. Twenty-one measures of at-work productivity loss, ranging from single item indicators to multidimensional scales, were reviewed for measurement properties. No set of at-work productivity measures was endorsed because of variability in the concepts captured, and the need for a better framework for the measurement of worker productivity that also incorporates contextual issues such as job demands and other paid and unpaid life responsibilities. Progress has been made in this area, revealing an ambivalent set of results that directed us back to the need to further define and then contextualize the measurement of worker productivity.

  2. HCTISN - Plenary extraordinary meeting on the 9 March 2012 - General consequences of the earthquake and tsunami; Status of Fukushima-Dai-ichi nuclear installations; The Fukushima accident, one year after: environmental and health situation in Japan; Protective actions undertaken by Japanese authorities; Support by AREVA to Japan after the Fukushima accident; What went on in Fukushima? Implementation of the IAEA nuclear safety action plan; Review of European stress tests by the peers; Opinion of the ASN on complementary safety assessments (CSAs)

    International Nuclear Information System (INIS)

    Kataoka, Susumu; Charles, T.; Champion, Didier; Jean-Luc Godet; Arnaud GAY; Philippe Jamet

    2012-01-01

    This document contains Power Point presentations proposed during a plenary session of the High Committee transparency and information on nuclear safety (HCTISN). The contributions addressed the Fukushima accident (the earthquake and the tsunami, the technical consequences on the plant, the consequences on the environment and on health, the different actions undertaken in Japan to protect the population, the consequences on nuclear safety in other countries with notably the performance of stress tests or the organisation of complementary safety assessments on the French fleet of nuclear reactors

  3. Wave grouping measures

    Energy Technology Data Exchange (ETDEWEB)

    Mansard, E.; Sand, S.E.; Klinting, P.

    1989-02-01

    There are recent indications that distinct wave groupings can be found even in deep water. The main objective has been to give a statistical description suitable for the design of coastal and offshore structures and it is undertaken to make further investigations in this field by analyzing some prototype records using the concepts of run length of high waves and spectrum of squared elevation, the limitations and performances of which in nonlinear waves will be highlighted in this study. An attempt has been made to relate this wave grouping to the surge motion of a floating structure with a simple mooring arrangement and thereby to propose a motion-based grouping measure. It appears that the observed run length statistics can be suitably described by Kimura's predictions if the records are sufficiently long. Records whose duration are equal to, or less than, 0.6 h reflect a large statistical variability in the various wave grouping measures. The filter cut-off proposed in the concept of SIWEH for the estimation of Groupiness Factor appears to be too high to give meaningful contrasts with respect to prototype values of the peakedness factors. It is therefore proposed to use the Hilbert Transform of the time series and a cut-off which is relevant to the natural period of the test structure. In the absence of information about this natural period a cut-off fc less than or equal to f/sub p//15 may work better. The motion equivalent groupiness factor concept could be used effectively to determine the critical sea state conditions to be used for testing of floating structures. The directional resolution of the sea state and theoretical formulations defining statistical variabilities caused by finite record lengths could be useful in evaluating whether the wave grouping is a linear process. (AB) 49 refs.

  4. Temperature measurement

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/003400.htm Temperature measurement To use the sharing features on this page, please enable JavaScript. The measurement of body temperature can help detect illness. It can also monitor ...

  5. Importance measures

    International Nuclear Information System (INIS)

    Gomez Cobo, A.

    1997-01-01

    The presentation discusses the following: general concepts of importance measures; example fault tree, used to illustrate importance measures; Birnbaum's structural importance; criticality importance; Fussel-Vesely importance; upgrading function; risk achievement worth; risk reduction worth

  6. Adaptation to High Ethanol Reveals Complex Evolutionary Pathways.

    Directory of Open Access Journals (Sweden)

    Karin Voordeckers

    2015-11-01

    Full Text Available Tolerance to high levels of ethanol is an ecologically and industrially relevant phenotype of microbes, but the molecular mechanisms underlying this complex trait remain largely unknown. Here, we use long-term experimental evolution of isogenic yeast populations of different initial ploidy to study adaptation to increasing levels of ethanol. Whole-genome sequencing of more than 30 evolved populations and over 100 adapted clones isolated throughout this two-year evolution experiment revealed how a complex interplay of de novo single nucleotide mutations, copy number variation, ploidy changes, mutator phenotypes, and clonal interference led to a significant increase in ethanol tolerance. Although the specific mutations differ between different evolved lineages, application of a novel computational pipeline, PheNetic, revealed that many mutations target functional modules involved in stress response, cell cycle regulation, DNA repair and respiration. Measuring the fitness effects of selected mutations introduced in non-evolved ethanol-sensitive cells revealed several adaptive mutations that had previously not been implicated in ethanol tolerance, including mutations in PRT1, VPS70 and MEX67. Interestingly, variation in VPS70 was recently identified as a QTL for ethanol tolerance in an industrial bio-ethanol strain. Taken together, our results show how, in contrast to adaptation to some other stresses, adaptation to a continuous complex and severe stress involves interplay of different evolutionary mechanisms. In addition, our study reveals functional modules involved in ethanol resistance and identifies several mutations that could help to improve the ethanol tolerance of industrial yeasts.

  7. Omics strategies for revealing Yersinia pestis virulence

    Science.gov (United States)

    Yang, Ruifu; Du, Zongmin; Han, Yanping; Zhou, Lei; Song, Yajun; Zhou, Dongsheng; Cui, Yujun

    2012-01-01

    Omics has remarkably changed the way we investigate and understand life. Omics differs from traditional hypothesis-driven research because it is a discovery-driven approach. Mass datasets produced from omics-based studies require experts from different fields to reveal the salient features behind these data. In this review, we summarize omics-driven studies to reveal the virulence features of Yersinia pestis through genomics, trascriptomics, proteomics, interactomics, etc. These studies serve as foundations for further hypothesis-driven research and help us gain insight into Y. pestis pathogenesis. PMID:23248778

  8. Measurement evaluation

    CERN Document Server

    Boros, A

    1990-01-01

    The information obtained about a measured object is called ``crude'' measurement information and must be related to the conditions under which the measurement took place. Using ``crude'' measurement information as a starting point, evaluation produces physically correctly interpreted data with their estimated (or corrected) error. Although a number of works deal with the evaluation of measurements, they either appeared a long time ago or serve essentially different aims. This book gives a comprehensive and current overview on the basic principles, aids, devices, and methods in the eval

  9. Comparing SessionStateReveal and EphemeralKeyReveal for Diffie-Hellman Protocols

    Science.gov (United States)

    Ustaoglu, Berkant

    Both the "eCK" model, by LaMacchia, Lauter and Mityagin, and the "CK01" model, by Canetti and Krawczyk, address the effect of leaking session specific ephemeral data on the security of key establishment schemes. The CK01-adversary is given a SessionStateReveal query to learn session-specific private data defined by the protocol specification, whereas the eCK-adversary is equipped with an EphemeralKeyReveal query to access all ephemeral private input required to carry session computations. SessionStateReveal cannot be issued against the test session; by contrast EphemeralKeyReveal can be used against the test session under certain conditions. On the other hand, it is not obvious how EphemeralKeyReveal compares to SessionStateReveal. Thus it is natural to ask which model is more useful and practically relevant.

  10. STORM-SEWER FLOW MEASUREMENT AND RECORDING SYSTEM.

    Science.gov (United States)

    Kilpatrick, Frederick A.; Kaehrle, William R.

    1986-01-01

    A comprehensive study and development of instruments and techniques for measuring all components of flow in a storm-sewer drainage system were undertaken by the U. S. Geological Survey under the sponsorship of FHWA. The study involved laboratory and field calibration and testing of measuring flumes, pipe insert meters, weirs, and electromagnetic velocity meters as well as the development and calibration of pneumatic bubbler and pressure transducer head-measuring systems. Tracer dilution and acoustic-flowmeter measurements were used in field verification tests. A single micrologger was used to record data from all the instruments and also to activate on command the electromagnetic velocity meter and tracer dilution systems.

  11. Monosomic analysis reveals duplicated chromosomal segments in ...

    Indian Academy of Sciences (India)

    Monosomic analysis reveals duplicated chromosomal segments in maize genome. MAHESH C. YADAV1,2∗, J. K. S. ... cated chromosomal segments in maize genome. Materials and methods. Development and .... each in chromosomes 2 and 7, while 10 other pairs of du- plicate loci had one copy in chromosome 3 and the ...

  12. [Scaphoid enchondroma revealed by a fracture].

    Science.gov (United States)

    El Mrini, A; Daoudi, A; Loudyi, D; Boutayeb, F; Agoumi, O; El Yaacoubi, M

    2006-06-01

    Enchondroma is a common bone tumor of hand. It is rarely localized in scaphoid. We report a new case of this tumor revealed by fracture. The diagnosis was suggested by standard radiography and confirmed then by anatomic pathology examination. Enucleation and bone graft with osteosynthesis yielded good result.

  13. Genetic relationship among Musa genotypes revealed by ...

    African Journals Online (AJOL)

    Genetic relationship among Musa genotypes revealed by microsatellite markers. NAP Abdullah, GB Saleh, ETS Putra, ZB Wahab. Abstract. A banana germplasm was established containing 44 Musa genotypes collected from various locations in Malaysia. To detect their genetic variation and to rule out duplicates among ...

  14. Commentary: Revealing the workings of universal grammar

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 28; Issue 5. Commentary: Revealing the workings of universal grammar. Mohinish Shukla. Volume 28 Issue 5 September 2003 pp 535-537. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/jbsc/028/05/0535-0537. Author Affiliations.

  15. Genomics analysis of genes expressed reveals differential ...

    African Journals Online (AJOL)

    Genomics analysis of genes expressed reveals differential responses to low chronic nitrogen stress in maize. ... Most induced clones were largely involved in various metabolism processes including physiological process, organelle regulation of biological process, nutrient reservoir activity, transcription regulator activity and ...

  16. Tanzania's Revealed Comparative Advantage and Structural ...

    African Journals Online (AJOL)

    This study examines Tanzania's structural transformation by using the revealed comparative approach using export data for 2001, 2002 and 2011, at the second level of the Harmonised. System (HS). Using global data, the study finds that for 2002 and 2011, agricultural products, fish and minerals have comparative ...

  17. Systemic lupus erythematous revealed by cytomegalovirus infection ...

    African Journals Online (AJOL)

    Cytomegalovirus (CMV) infection have been described as exacerbing systemic lupus erythematous (SLE). The role of CMV in starting off SLE remains object of debate. We report a severe presentation of SLE revealed by CMV infection with hemophogocytic syndrome. A 22 old women without a history of systemic disease ...

  18. Eye Movements Reveal Dynamics of Task Control

    Science.gov (United States)

    Mayr, Ulrich; Kuhns, David; Rieter, Miranda

    2013-01-01

    With the goal to determine the cognitive architecture that underlies flexible changes of control settings, we assessed within-trial and across-trial dynamics of attentional selection by tracking of eye movements in the context of a cued task-switching paradigm. Within-trial dynamics revealed a switch-induced, discrete delay in onset of…

  19. Quantum measurement

    CERN Document Server

    Busch, Paul; Pellonpää, Juha-Pekka; Ylinen, Kari

    2016-01-01

    This is a book about the Hilbert space formulation of quantum mechanics and its measurement theory. It contains a synopsis of what became of the Mathematical Foundations of Quantum Mechanics since von Neumann’s classic treatise with this title. Fundamental non-classical features of quantum mechanics—indeterminacy and incompatibility of observables, unavoidable measurement disturbance, entanglement, nonlocality—are explicated and analysed using the tools of operational quantum theory. The book is divided into four parts: 1. Mathematics provides a systematic exposition of the Hilbert space and operator theoretic tools and relevant measure and integration theory leading to the Naimark and Stinespring dilation theorems; 2. Elements develops the basic concepts of quantum mechanics and measurement theory with a focus on the notion of approximate joint measurability; 3. Realisations offers in-depth studies of the fundamental observables of quantum mechanics and some of their measurement implementations; and 4....

  20. Gaussian graphical modeling reveals specific lipid correlations in glioblastoma cells

    Science.gov (United States)

    Mueller, Nikola S.; Krumsiek, Jan; Theis, Fabian J.; Böhm, Christian; Meyer-Bäse, Anke

    2011-06-01

    Advances in high-throughput measurements of biological specimens necessitate the development of biologically driven computational techniques. To understand the molecular level of many human diseases, such as cancer, lipid quantifications have been shown to offer an excellent opportunity to reveal disease-specific regulations. The data analysis of the cell lipidome, however, remains a challenging task and cannot be accomplished solely based on intuitive reasoning. We have developed a method to identify a lipid correlation network which is entirely disease-specific. A powerful method to correlate experimentally measured lipid levels across the various samples is a Gaussian Graphical Model (GGM), which is based on partial correlation coefficients. In contrast to regular Pearson correlations, partial correlations aim to identify only direct correlations while eliminating indirect associations. Conventional GGM calculations on the entire dataset can, however, not provide information on whether a correlation is truly disease-specific with respect to the disease samples and not a correlation of control samples. Thus, we implemented a novel differential GGM approach unraveling only the disease-specific correlations, and applied it to the lipidome of immortal Glioblastoma tumor cells. A large set of lipid species were measured by mass spectrometry in order to evaluate lipid remodeling as a result to a combination of perturbation of cells inducing programmed cell death, while the other perturbations served solely as biological controls. With the differential GGM, we were able to reveal Glioblastoma-specific lipid correlations to advance biomedical research on novel gene therapies.

  1. Measuring competitiveness

    OpenAIRE

    J. Peter Neary

    2005-01-01

    An earlier version was presented at the Conference on Macroeconomic Perspectives in Honour of Brendan M. Walsh, held at University College Dublin on 7 October, 2005 This paper reviews alternative approaches to measuring an economy?s cost competitiveness and proposes some new measures inspired by the economic theory of index numbers. The indices provide a theoretical benchmark for estimated real effective exchange rates, but differ from standard measures in that they are based on marginal r...

  2. Transcriptome Reveals Cathepsin K in Periodontal Ligament Differentiation.

    Science.gov (United States)

    Yamada, S; Ozaki, N; Tsushima, K; Yamaba, S; Fujihara, C; Awata, T; Sakashita, H; Kajikawa, T; Kitagaki, J; Yamashita, M; Yanagita, M; Murakami, S

    2016-08-01

    Periodontal ligaments (PDLs) play an important role in remodeling the alveolar bond and cementum. Characterization of the periodontal tissue transcriptome remains incomplete, and an improved understanding of PDL features could aid in developing new regenerative therapies. Here, we aimed to generate and analyze a large human PDL transcriptome. We obtained PDLs from orthodontic treatment patients, isolated the RNA, and used a vector-capping method to make a complementary DNA library from >20,000 clones. Our results revealed that 58% of the sequences were full length. Furthermore, our analysis showed that genes expressed at the highest frequencies included those for collagen type I, collagen type III, and proteases. We also found 5 genes whose expressions have not been previously reported in human PDL. To access which of the highly expressed genes might be important for PDL cell differentiation, we used real-time polymerase chain reaction to measure their expression in differentiating cells. Among the genes tested, the cysteine protease cathepsin K had the highest upregulation, so we measured its relative expression in several tissues, as well as in osteoclasts, which are known to express high levels of cathepsin K. Our results revealed that PDL cells express cathepsin K at similar levels as osteoclasts, which are both expressed at higher levels than those of the other tissues tested. We also measured cathepsin K protein expression and enzyme activity during cell differentiation and found that both increased during this process. Immunocytochemistry experiments revealed that cathepsin K localizes to the interior of lysosomes. Last, we examined the effect of inhibiting cathepsin K during cell differentiation and found that cathepsin K inhibition stimulated calcified nodule formation and increased the levels of collagen type I and osteocalcin gene expression. Based on these results, cathepsin K seems to regulate collagen fiber accumulation during human PDL cell

  3. Hyposplenism revealed by Plasmodium malariae infection

    OpenAIRE

    Hommel, Benjamin; Galloula, Alexandre; Simon, Anne; Buffet, Pierre

    2013-01-01

    International audience; BACKGROUND: Hyposplenism, due to splenectomy, inherited red blood cell disorders or acquired conditions such as celiac disease, has an important impact on the severity of malaria, especially in non-immune patients. Conversely, that malaria may reveal functional hyposplenism has not been described previously. METHODS: A 31-year old gardener was diagnosed with an uncomplicated attack of Plasmodium malariae 11 years after leaving the endemic area. In addition to trophozoi...

  4. Fluorescent sensors reveal subcellular thermal changes.

    OpenAIRE

    Sakaguchi, Reiko; Kiyonaka, Shigeki; Mori, Yasuo

    2014-01-01

    In mammals and birds, thermoregulation to conserve body temperature is vital to life. Multiple mechanisms of thermogeneration have been proposed, localized in different subcellular organelles. However, studying thermogenesis directly in intact organelles has been challenging. Visualizing patterns of thermal changes at subcellular resolution would reveal physiologically relevant spatio-temporal information, especially if this could be done in the native cellular configuration of the cell. Here...

  5. Mediastinal Mature Teratoma Revealed by Empyema

    Directory of Open Access Journals (Sweden)

    Mohammed Raoufi

    2016-01-01

    Full Text Available Teratomas are germ cell tumors, manifested with a great variety of clinical features; the most common extragonadal site is the anterior mediastinum. In this case, we report the patient with a large mature mediastinal teratoma with several components of ectodermal and endothermal epithelium. A 24-year-old female patient presented with history of persistent chest pain and progressively aggravating dyspnea for the previous 3 months. A chest X-ray showed a large opacity of the entire left hemithorax. Transcutaneous needle aspiration revealed a purulent fluid. The tube thoracostomy was introduced and the effusion was evacuated. Some weeks later, patient was seen in emergency for persistent cough and lateral chest pain. CT scan revealed a mass of the left hemithorax. The mass showed heterogeneous density, without compressing mediastinum great vessels and left hilar structures. Lipase value was elevated in needle aspiration. The patient underwent a total resection of the mediastinum mass via a left posterolateral thoracotomy. Microscopy revealed a mature teratoma with cystic structures. The patient subsequently made a full recovery. This case provide benign mediastinal teratoma with total atelectasis of left lung and elevated lipase value in needle transcutaneous aspiration; this event is explained by pancreatic component in the cystic tumor. Total removal of the tumor is adequate treatment for this type of teratoma and the prognosis is excellent.

  6. Comparing the lived experience to objective measures of Accessibility

    OpenAIRE

    Angela Curl; John Nelson; Jillian Anable

    2011-01-01

    This paper presents work undertaken to date as part of PhD research into the process of Accessibility Planning in the UK and how existing objective measures of accessibility relate to individual perceptions or the "lived experience" of accessibility. Since 1997, Accessibility has been framed in the social exclusion context within UK transport planning and policy, focusing on the ability of people to participate fully in society, which is seen as being limited by poor accessibility. This appro...

  7. Influence of Sulfolane on ESI-MS Measurements of Protein-Ligand Affinities

    Science.gov (United States)

    Yao, Yuyu; Richards, Michele R.; Kitova, Elena N.; Klassen, John S.

    2016-03-01

    The results of an investigation into the influence of sulfolane, a commonly used supercharging agent, on electrospray ionization mass spectrometry (ESI-MS) measurements of protein-ligand affinities are described. Binding measurements carried out on four protein-carbohydrate complexes, lysozyme with β- d-GlcNAc-(1→4)-β- d-GlcNAc-(1→4)-β- d-GlcNAc-(1→4)- d-GlcNAc, a single chain variable fragment and α- d-Gal-(1→2)-[α- d-Abe-(1→3)]-α- d-Man-OCH3, cholera toxin B subunit homopentamer with β- d-Gal-(1→3)-β- d-GalNAc-(1→4)[α- d-Neu5Ac-(2→3)]-β- d-Gal-(1→4)-β- d-Glc, and a fragment of galectin 3 and α- l-Fuc-(1→2)-β- d-Gal-(1→3)-β- d-GlcNAc-(1→3)-β- d-Gal-(1→4)-β- d-Glc, revealed that sulfolane generally reduces the apparent (as measured by ESI-MS) protein-ligand affinities. To establish the origin of this effect, a detailed study was undertaken using the lysozyme-tetrasaccharide interaction as a model system. Measurements carried out using isothermal titration calorimetry (ITC), circular dichroism, and nuclear magnetic resonance spectroscopies reveal that sulfolane reduces the binding affinity in solution but does not cause any significant change in the higher order structure of lysozyme or to the intermolecular interactions. These observations confirm that changes to the structure of lysozyme in bulk solution are not responsible for the supercharging effect induced by sulfolane. Moreover, the agreement between the ESI-MS and ITC-derived affinities indicates that there is no dissociation of the complex during ESI or in the gas phase (i.e., in-source dissociation). This finding suggests that supercharging of lysozyme by sulfolane is not related to protein unfolding during the ESI process. Binding measurements performed using liquid sample desorption ESI-MS revealed that protein supercharging with sulfolane can be achieved without a reduction in affinity.

  8. Revealing structure within the coronae of Seyfert galaxies

    Science.gov (United States)

    Wilkins, D.

    2017-10-01

    Detailed analysis of the reflection and reverberation of X-rays from the innermost regions of AGN accretion discs reveals the structure and processes that produce the intense continuum emission and the extreme variability we see, right down to the innermost stable orbit and event horizon of the black hole. Observations of Seyfert galaxies spanning more than a decade have enabled measurement of the geometry of the corona and how it evolves, leading to orders of magnitude of variability. They reveal processes the corona undergoes during transient events, notably the collimation and ejection of the corona during X-ray flares, reminiscent of the aborted launching of a jet. Recent reverberation studies, including those of the Seyfert galaxy I Zwicky 1 with XMM-Newton, are revealing structures within the corona for the first time. A persistent collimated core is found, akin to the base of a jet embedded in the innermost regions. The evolution of both the collimated and extended portions point to the mechanisms powering the X-ray emission and variability. This gives us important constraints on the processes by which energy is liberated from black hole accretion flows and by which jets are launched, allowing us to understand how these extreme objects are powered.

  9. The coming and going of a marl lake: multi-indicator palaeolimnology reveals abrupt ecological change and alternative views of reference conditions

    Directory of Open Access Journals (Sweden)

    Emma eWiik

    2015-08-01

    Full Text Available Eutrophication is the most pressing threat to highly calcareous (marl lakes in Europe. Despite their unique chemistry and biology, comprehensive studies into their unimpacted conditions and eutrophication responses are underrepresented in conservation literature. A multi-indicator palaeolimnological study spanning ca 1260 to 2009 was undertaken at Cunswick Tarn (UK, a small, presently eutrophic marl lake, in order to capture centennial timescales of impact. Specific aims were to 1 establish temporal patterns of change (gradual/abrupt across biological groups, thereby testing theories of resistance of marl lake benthic communities to enrichment, and 2 compare the core record of reference condition with prevailing descriptions of high ecological status. Analyses of sediment calcium (Ca, phosphorus (P, pigments, diatoms, testate amoebae, cladocerans, and macrofossils, revealed three abrupt changes in ecosystem structure. The first (1900s, with biomass increases in charophytes and other benthic nutrient-poor indicators, supported ideas of resistance to eutrophication in Chara lakes. The second transition (1930s, from charophyte to angiosperm dominance, occurred alongside reductions in macrophyte cover, increases in eutrophic indicators, and a breakdown in marling, in support of ideas of threshold responses to enrichment. Core P increased consistently into the 1990s when rapid transitions into pelagic shallow lake ecology occurred and Cunswick Tarn became biologically unidentifiable as a marl lake. The moderate total P at which these changes occurred suggests high sensitivity of marl lakes to eutrophication. Further, the early record challenges ideas of correlation between ecological condition, charophyte biomass and sediment Ca. Instead, low benthic production, macrophyte cover, and Ca sedimentation, was inferred. Management measures must focus on reducing external nutrient and sediment loads at early stages of impact in order to preserve marl lakes.

  10. Ordinance on measures for preparation of a radioactive waste repository (Ordinance on preparatory measures) of 24 October 1979

    International Nuclear Information System (INIS)

    1981-01-01

    This Ordinance contains details concerning the special procedure provided for under Section 10(2) of the Federal Order of 6th October 1978 concerning the Atomic Energy Act whereby the Federal Council must grant permission before preparations for the construction of radioactive waste repositories may be undertaken. The Ordinance defines the preparatory measures, which include maps and plans of the area, a geological report, etc. (NEA) [fr

  11. Measuring Colour

    CERN Document Server

    Hunt, R W G

    2011-01-01

    The classic authority on colour measurement now fully revised and updated with the latest CIE recommendations The measurement of colour is of major importance in many commercial applications, such as the textile, paint, and foodstuff industries; as well as having a significant role in the lighting, paper, printing, cosmetic, plastics, glass, chemical, photographic, television, transport, and communication industries. Building upon the success of earlier editions, the 4th edition of Measuring Colour has been updated throughout with new chapters on colour rendering by light sources; colorimetry

  12. Mechanical measurements

    CERN Document Server

    Venkateshan, S P

    2015-01-01

    The first edition of this book was co-published by Ane Books India, and CRC Press in 2008. This second edition is an enlarged version of the web course developed by the author at IIT Madras, and also a modified and augmented version of the earlier book.  Major additions/modifications presented are in the treatment of errors in measurement, temperature measurement, measurement of thermo-physical properties, and data manipulation. Many new worked examples have been introduced in this new and updated second edition. 

  13. Sharp Vision Reveals Intimacy of Stars

    Science.gov (United States)

    2005-11-01

    Sharp Vision Reveals Intimacy of Stars AMBER instrument on VLTI Probes Environment of Stars Using the newly installed AMBER instrument on ESO's Very Large Telescope Interferometer, which combines the light from two or three 8.2-m Unit Telescopes thereby amounting to observe with a telescope of 40 to 90 metres in diameter, two international teams of astronomers observed with unprecedented detail the environment of two stars. One is a young, still-forming star and the new results provide useful information on the conditions leading to the creation of planets. The other is on the contrary a star entering the latest stages of its life. The astronomers found, in both cases, evidence for a surrounding disc. ESO PR Photo 36a/05 ESO PR Photo 36a/05 The Young Stellar Object MWC 297 (Artist's View) [Preview - JPEG: 400 x 502 pix - 50k] [Normal - JPEG: 800 x 1004 pix - 330k] A first group of astronomers [1], led by Fabien Malbet from the Laboratoire d'Astrophysique de Grenoble, France, studied the young 10-solar mass stellar object MWC 297, which is still in the very early stage of its life [2]. "This scientific breakthrough opens the doors to an especially detailed scrutiny of the very close environment of young stars and will bring us invaluable knowledge on how planets form", says Malbet. It is amazing to see the amount of details the astronomers could achieve while observing an object located more than 800 light-years away and hidden by a large amount of gas and dust. They found the object to be surrounded by a proto-planetary disc extending to about the size of our Solar System, but truncated in his inner part until about half the distance between the Earth and the Sun. Moreover, the scientists found the object to be surrounded by an outflowing wind, the velocity of which increased by a factor 9, from about 70 km/s near the disc to 600 km/s in the polar regions [3]. "The reason why the inner part of the disc should be truncated is not clear", adds Malbet. "This raises

  14. Measured MHD equilibrium in Alcator C

    International Nuclear Information System (INIS)

    Pribyl, P.A.

    1986-03-01

    A method of processing data from a set of partial Rogowski loops is developed to study the MHD equilibrium in Alcator C. Time dependent poloidal fields in the vicinity of the plasma are calculated from measured currents, with field penetration effects being accounted for. Fields from eddy currents induced by the plasma in the tokamak structure are estimated as well. Each of the set of twelve B/sub θ/ measurements can then be separated into a component from the plasma current and a component from currents external to the pickup loops. Harmonic solutions to Maxwell's equations in toroidal coordinates are fit to these measurements in order to infer the fields everywhere in the vacuum region surrounding the plasma. Using this diagnostic, plasma current, position, shape, and the Shafranov term Λ = β/sub p/ + l/sub i//2 - 1 may be computed, and systematic studies of these plasma parameters are undertaken for Alcator C plasmas

  15. Measuring colour

    National Research Council Canada - National Science Library

    Hunt, R. W. G; Pointer, Michael, Ph. D

    2011-01-01

    ... industries.Building upon the success of earlier editions, the 4th edition of [start italics]Measuring Colour[end italics] has been updated throughout with new chapters on colour rendering by light sources...

  16. Environmental Measurement

    Science.gov (United States)

    Environmental measurement is any data collection activity involving the assessment of chemical, physical, or biological factors in the environment which affect human health. Learn more about these programs and tools that aid in environmental decisions

  17. Horizon measures

    KAUST Repository

    Zhang, Eugene

    2016-11-28

    In this paper we seek to answer the following question: where do contour lines and visible contour lines (silhouette) tend to occur in a 3D surface. Our study leads to two novel shape descriptors, the horizon measure and the visible horizon measure, which we apply to the visualization of 3D shapes including archeological artifacts. In addition to introducing the shape descriptors, we also provide a closed-form formula for the horizon measure based on classical spherical geometry. To compute the visible horizon measure, which depends on the exact computation of the surface visibility function, we instead of provide an image-based approach which can process a model with high complexity within a few minutes.

  18. Lifetime measurements

    International Nuclear Information System (INIS)

    Fossan, D.B.; Warburton, E.K.

    1974-01-01

    Lifetime measurements are discussed, concentrating on the electronic technique, the recoil distance method (RDM), and the Doppler shift attenuation method (DSAM). A brief review of several indirect timing techniques is given, and their specific advantages and applicability are considered. The relationship between lifetimes of nuclear states and the nuclear structure information obtained from them is examined. A short discussion of channeling and microwave methods of lifetime measurement is presented. (23 figures, 171 references) (U.S.)

  19. Anthropomorphic measurements

    International Nuclear Information System (INIS)

    Wang, J.

    1998-01-01

    Based on decisions taken during the Research Coordination Meetings in Mito City 1988 and Bombay 1991, the participants were requested to provide data on physical measurement parameters of body height, body weight, sitting height, head circumference, neck circumference, chest circumference, chest width and chest depth which represented the age groups as newborn, 1 year, 5 years, 10 years, 15 years and adult 20-50 years. Accordingly, physical measurement data was obtained by participants from 9 countries

  20. Measurements of blade aerodynamics on a rotor in the field

    Energy Technology Data Exchange (ETDEWEB)

    Graham, J.M.R. [Imperical College, Dept. of Aeronautics, London (United Kingdom)

    1997-12-31

    This contribution describes the field test measurements undertaken on an instrumented rotor at the Rutherford Appleton Laboratory, Oxfordshire, UK, during the period 1994 - 97. The programme was directed at improving the prediction of the steady and unsteady rotor blade loading, particularly the loads arising from the stalling of the blade. The measured data consisted of blade surface pressure distributions sampled at 50Hz at 6 sections along the span of one blade of the 17m diameter, 3 bladed, fixed pitch, upwind H.A.W.T., together with measurements of the incident velocity. (au)

  1. Midface swelling reveals nasofrontal dermal sinus

    International Nuclear Information System (INIS)

    Houneida, Zaghouani Ben Alaya; Manel, Limeme; Latifa, Harzallah; Habib, Amara; Dejla, Bakir; Chekib, Kraiem

    2012-01-01

    Nasofrontal dermal sinuses are very rare and generally occur in children. This congenital malformation can be revealed by midface swelling, which can be complicated by local infection or neuromeningitis. Such complications make the dermal sinus a life-threatening disease. Two cases of nasofrontal dermal sinuses are reported in this work. The first case is an 11-month-old girl who presented with left orbitonasal soft tissue swelling accompanied by inflammation. Physical examination found fever, left orbitonasal thickening, and a puncture hole letting out pus. Computed tomography revealed microabscesses located at the left orbitonasal soft tissues, a frontal bone defect, and an intracranial cyst. Magnetic resonance imaging showed the transosseous tract between the glabella and the brain and affirmed the epidermoid nature of the intracranial cyst. The second case is a 7-year-old girl who presented with a nasofrontal non-progressive mass that intermittently secreted a yellow liquid through an external orifice located at the glabella. MRI revealed a cystic mass located in the deep layer of the glabellar skin related to an epidermoid cyst with a nasofrontal dermal sinus tract. In both cases, surgical excision was performed, and pathological confirmation was made for the diagnoses of dermal sinuses. The postoperative course was favorable. Through these cases, the authors stress the role of imaging methods in confirming the diagnosis and looking for associated cysts (dermoid and epidermoid) to improve recognition of this rare disease. Knowledge of the typical clinical presentations, imaging manifestations, and most common sites of occurrence of this malformation are needed to formulate a differential diagnosis.

  2. Infections Revealing Complement Deficiency in Adults

    Science.gov (United States)

    Audemard-Verger, A.; Descloux, E.; Ponard, D.; Deroux, A.; Fantin, B.; Fieschi, C.; John, M.; Bouldouyre, A.; Karkowsi, L.; Moulis, G.; Auvinet, H.; Valla, F.; Lechiche, C.; Davido, B.; Martinot, M.; Biron, C.; Lucht, F.; Asseray, N.; Froissart, A.; Buzelé, R.; Perlat, A.; Boutboul, D.; Fremeaux-Bacchi, V.; Isnard, S.; Bienvenu, B.

    2016-01-01

    Abstract Complement system is a part of innate immunity, its main function is to protect human from bacterial infection. As genetic disorders, complement deficiencies are often diagnosed in pediatric population. However, complement deficiencies can also be revealed in adults but have been poorly investigated. Herein, we describe a case series of infections revealing complement deficiency in adults to study clinical spectrum and management of complement deficiencies. A nationwide retrospective study was conducted in French university and general hospitals in departments of internal medicine, infectious diseases enrolling patients older than 15 years old who had presented at least one infection leading to a complement deficiency diagnosis. Forty-one patients included between 2002 and 2015 in 19 different departments were enrolled in this study. The male-to-female ratio was 1.3 and the mean age at diagnosis was 28 ± 14 (15–67) years. The main clinical feature was Neisseria meningitidis meningitis 75% (n = 31/41) often involving rare serotype: Y (n = 9) and W 135 (n = 7). The main complement deficiency observed was the common final pathway deficiency 83% (n = 34/41). Half of the cohort displayed severe sepsis or septic shock at diagnosis (n = 22/41) but no patient died. No patient had family history of complement deficiency. The mean follow-up was 1.15 ± 1.95 (0.1–10) years. Half of the patients had already suffered from at least one infection before diagnosis of complement deficiency: meningitis (n = 13), pneumonia (n = 4), fulminans purpura (n = 1), or recurrent otitis (n = 1). Near one-third (n = 10/39) had received prophylactic antibiotics (cotrimoxazole or penicillin) after diagnosis of complement deficiency. The vaccination coverage rate, at the end of the follow-up, for N meningitidis, Streptococcus pneumonia, and Haemophilius influenzae were, respectively, 90% (n = 33/37), 47% (n = 17/36), and 35

  3. ltnear carcass measurements as indicators of body fat content in the ...

    African Journals Online (AJOL)

    duiders van totale liggaamsvet in die vark. SUMMARY: This study was undertaken to investigate the suitability of various carcass fat measurements as predictors of total body fat in the pig in order to minimize the time, labour and costs involved in carcas evaluation techniques. A total of 33 Landrace X L,arge White crossbred ...

  4. Off-line sampling of exhaled air for nitric oxide measurement in children: methodological aspects

    NARCIS (Netherlands)

    Q. Jobsis (Quirijn); S.L. Schellekens; A. Kroesbergen; W.C.J. Hop (Wim); J.C. de Jongste (Johan)

    2001-01-01

    textabstractMeasurement of nitric oxide in exhaled air is a noninvasive method to assess airway inflammation in asthma. This study was undertaken to establish the reference range of exhaled NO in healthy school-aged children and to determine the influence of ambient NO, noseclip

  5. Measuring Physical Activity in Children and Youth Living with Intellectual Disabilities: A Systematic Review

    Science.gov (United States)

    Hinckson, Erica Aneke; Curtis, Amy

    2013-01-01

    Accurate assessment of physical activity is necessary in determining levels of physical activity in children living with intellectual disability (ID) and assessing effectiveness of intervention programmes. A systematic review of measures of physical activity in children with ID was undertaken using the PRISMA guidelines. MEDLINE-PubMed, Scopus,…

  6. Wind atlas for South Africa: wind measurements and micro-scale modelling

    CSIR Research Space (South Africa)

    Szewczuk, S

    2010-08-01

    Full Text Available . This paper will discuss the wind atlas method, provide an overview of the wind resource in South Africa, wind measurements that are being undertaken as well as the micro-scale modelling that is planned to be done as part of the Wind Atlas for South Africa...

  7. Emission of toxic organic microcontaminants from ship's engines: first measurements on three cruising ships

    NARCIS (Netherlands)

    Compaan, H.; Rhemrev, M.M.; Houtzager, M.M.G.

    1992-01-01

    This work was undertaken within the framework of Lloyd's Register's Marine Exhaust Emissions Research Programme. Phase II of this research programme [] evaluated exhaust emissions from ships in service under steady state and transient modes of operation and incorporated measurements of CO, CO2, 02,

  8. Measuring Confidence Levels of Male and Female Students in Open Access Enabling Courses

    Science.gov (United States)

    Atherton, Mirella

    2015-01-01

    The study of confidence was undertaken at the University of Newcastle with students selecting science courses at two campuses. The students were enrolled in open access programs and aimed to gain access to undergraduate studies in various disciplines at University. The "third person effect" was used to measure the confidence levels of…

  9. Artificial Intelligence Measurement System, Overview and Lessons Learned. Final Project Report.

    Science.gov (United States)

    Baker, Eva L.; Butler, Frances A.

    This report summarizes the work conducted for the Artificial Intelligence Measurement System (AIMS) Project which was undertaken as an exploration of methodology to consider how the effects of artificial intelligence systems could be compared to human performance. The research covered four areas of inquiry: (1) natural language processing and…

  10. Measuring needs

    Directory of Open Access Journals (Sweden)

    Laura Murianni

    2008-06-01

    Full Text Available The interest in measuring the health of populations, through measuring the demand and offers of health care, is deeply rooted in history. Population health indicators in use today are built upon from mortality measures from the 1500s; regular census information starting from the 1800s; civil registration records of vital statistics commencing in the 1850s; regular national surveys, which were first initiated in the 1950s; and health system and other administrative databases used widely since the 1960s. The ancient Greeks believed that the God of medicine had two daughters: Hygeia and Panacea, the first was the goddess of prevention and wellness, while the second was the goddess of treatment. Thus suggesting that people have long believed that there is more to health than health care. Today the actual concept of population health recognizes many interconnected aspects of society, the environment, and individuals all contributing to health. To increase opportunities for comparability, more valid, comprehensive and standardized ways of measuring and reporting on population health indicators are needed. The use of health indicators contributes to overall population health goals, namely improving the health populations, reducing health inequalities and measuring the performance of health care system. The objective of performance assessment is to provide governments and populations with information about the state of their health care system.

  11. Against 'measurement'

    International Nuclear Information System (INIS)

    Bell, John

    1990-01-01

    This author of this article rails against the term ''measurement'' as it is commonly used in quantum mechanics. Many terms such as this are full of common place, everyday associations which are entirely inappropriate to the quantum world and lead to misunderstanding even amongst physicists. Measurement implies, at least for laboratory experiments, that the complexities of the real world have been simplified to the minimum number of variables. This can never be so for quantum mechanics where the act of measurement is intrinsic to the result, where even the mind of the observer plays a part. Three books on quantum mechanics are reviewed in an attempt to present a more precise comprehension of the meaning inside quantum mechanics. (UK)

  12. Load Measurements

    DEFF Research Database (Denmark)

    Kock, Carsten Weber; Vesth, Allan

    The report describes Load measurements carried out on a given wind turbine. The aim of the measurement program regarding the loads on the turbine is to verify the basic characteristics of the wind turbine and loads on the blades, the rotor and the tower, using [Ref 1], [Ref2] and [Ref 3]. Regarding...... the fatigue loads, the rotor, blades and tower moments are presented. The fatigue loads are evaluated using rainflow counting described in detail in Ref. [1]. The 1Hz equivalent load ranges are calculated at different wind speeds. All information regarding the instrumentation is collected in [ref 4] and [ref...

  13. Microwave Measurements

    CERN Document Server

    Skinner, A D

    2007-01-01

    The IET has organised training courses on microwave measurements since 1983, at which experts have lectured on modern developments. Their lecture notes were first published in book form in 1985 and then again in 1989, and they have proved popular for many years with a readership beyond those who attended the courses. The purpose of this third edition of the lecture notes is to bring the latest techniques in microwave measurements to this wider audience. The book begins with a survey of the theory of current microwave circuits and continues with a description of the techniques for the measureme

  14. SAFETY MEASURES

    CERN Multimedia

    Relations with the Host States Service; Tel. 75152

    2001-01-01

    Following the recent terrorist attacks, the French authorities have introduced increased-vigilance measures («Vigipirate renforcé») as part of their prevention of terrorism campaign and have expressed the wish to extend these measures to the French part of the CERN site. The Organization has acceded to this request with the understanding that its international status will be respectd and has granted the French Gendarmerie right of access to the Prévessin site and to the LEP/LHC sites on French territory.

  15. Broadcast copies reveal the quantumness of correlations.

    Science.gov (United States)

    Piani, M; Christandl, M; Mora, C E; Horodecki, P

    2009-06-26

    We study the quantumness of bipartite correlations by proposing a quantity that combines a measure of total correlations-mutual information-with the notion of broadcast copies-i.e., generally nonfactorized copies-of bipartite states. By analyzing how our quantity increases with the number of broadcast copies, we are able to classify classical, separable, and entangled states. This motivates the definition of the broadcast regularization of mutual information, the asymptotic minimal mutual information per broadcast copy, which we show to have many properties of an entanglement measure.

  16. AMS measurements

    International Nuclear Information System (INIS)

    Lawson, E.M.

    1999-01-01

    Accelerator mass spectrometry (AMS) ia an ultrasensitive analysis technique using a system based on a nuclear particle accelerator and its beam transport system to detect and measure individual 14 C ions.. In AMS a 14 C abundance is obtained by comparing the measurement rates of 14 C and 13 C ions. This is not as simple as it sounds. The enormous difference in the numbers of the two isotopes makes it very hard to uniquely detect 14 C ions. For modern samples, those with the most 14 C, some 10 10 13 C ions leave the source for every 14 C ion. However, the use of an accelerator and various high energy techniques makes it possible to the detect the 14 C and to reject the 13 C. in order to achieve this high rejection efficiency the injection magnet is set to transmit only one isotope, namely 14 C. However, a subsequent measurement of 13 C must be made. The number and the rate of arrival of 13 C ions is such that individual ions cannot be measured, instead a 13 C current is measured in a Faraday cup. It is possible to alternate the injection magnet field between that to transmit 14 C and that to transmit 13 C. This method is known as slow cycling but suffers from significant dead (not useful) periods while the magnet field is changed and stabilises. Furthermore and more significantly, during this dead time changes in ion source output may occur distorting the 14 C/ 13 C ratio. We instead employ a method known as fast cycling which involves rapidly increasing the energy of the 13 C ions as they enter the injection magnet. This is achieved by the use of a high voltage (6.7 kV) pulser. We can also inject 12 C by this method although a 14.7 kV pulse is required. The switching time from one carbon isotope to another is only a fraction of a millisecond in this fast cycling method. Hence one has quasi-simultaneous measurement of 14 C and 13 C. Measurements of the 14 C/ 13 C ratio from a sample are always compared to the same ratio from an internationally accepted standard

  17. Measuring Idiosyncratic Risk

    DEFF Research Database (Denmark)

    Sunesen, Eva Rytter

    and Latin American countries, but the idiosyncratic risk factor also represents a larger share than in other developing countries. As a final contribution, we search the empirical literature on foreign direct investment and risk in order to determine which of the suggested risk measures provide the best...... for the systematic components due to the global and regional interdependence between alternative investment locations. The decomposition of conditional risk into its systematic and idiosyncratic components reveals that not only are African countries on average characterised by a larger conditional risk than Asian...

  18. Neutron Imaging Reveals Internal Plant Hydraulic Dynamics

    Energy Technology Data Exchange (ETDEWEB)

    Warren, Jeffrey [ORNL; Bilheux, Hassina Z [ORNL; Kang, Misun [ORNL; Voisin, Sophie [ORNL; Cheng, Chu-Lin [ORNL; Horita, Jusuke [ORNL; Perfect, Edmund [ORNL

    2013-01-01

    Many terrestrial ecosystem processes are constrained by water availability and transport within the soil. Knowledge of plant water fluxes is thus critical for assessing mechanistic processes linked to biogeochemical cycles, yet resolution of root structure and xylem water transport dynamics has been a particularly daunting task for the ecologist. Through neutron imaging, we demonstrate the ability to non-invasively monitor individual root functionality and water fluxes within Zea mays L. (maize) and Panicum virgatum L. (switchgrass) seedlings growing in a sandy medium. Root structure and growth were readily imaged by neutron radiography and neutron computed tomography. Seedlings were irrigated with water or deuterium oxide and imaged through time as a growth lamp was cycled on to alter leaf demand for water. Sub-millimeter scale resolution reveals timing and magnitudes of root water uptake, redistribution within the roots, and root-shoot hydraulic linkages, relationships not well characterized by other techniques.

  19. [Localized purpura revealing vascular prosthetic graft infection].

    Science.gov (United States)

    Boureau, A S; Lescalie, F; Cassagnau, E; Clairand, R; Connault, J

    2013-07-01

    Prosthetic graft infection after vascular reconstruction is a rare but serious complication. We report a case of infection occurring late after implantation of an iliofemoral prosthetic vascular graft. The Staphylococcus aureus infection was revealed by vascular purpura localized on the right leg 7 years after implantation of a vascular prosthesis. This case illustrates an uncommonly late clinical manifestation presenting as an acute infection 7 years after the primary operation. In this situation, the presentation differs from early infection, which generally occurs within the first four postoperative months. Diagnosis and treatment remain a difficult challenge because prosthetic graft infection is a potentially life-threatening complication. Morbidity and mortality rates are high. Here we detail specific aspects of the clinical and radiological presentation. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

  20. Social patterns revealed through random matrix theory

    Science.gov (United States)

    Sarkar, Camellia; Jalan, Sarika

    2014-11-01

    Despite the tremendous advancements in the field of network theory, very few studies have taken weights in the interactions into consideration that emerge naturally in all real-world systems. Using random matrix analysis of a weighted social network, we demonstrate the profound impact of weights in interactions on emerging structural properties. The analysis reveals that randomness existing in particular time frame affects the decisions of individuals rendering them more freedom of choice in situations of financial security. While the structural organization of networks remains the same throughout all datasets, random matrix theory provides insight into the interaction pattern of individuals of the society in situations of crisis. It has also been contemplated that individual accountability in terms of weighted interactions remains as a key to success unless segregation of tasks comes into play.

  1. Wegener Granulomatosis Revealed by Pleural Effusion

    Science.gov (United States)

    Toffart, Anne-Claire; Arbib, François; Lantuejoul, Sylvie; Roux, Jean-François; Bland, Vincent; Ferretti, Gilbert; Diab, Samia

    2009-01-01

    Pulmonary signs are common in Wegener's granulomatosis (WG). However, an initial presentation including pleural effusion has not been described. We describe a case of WG in which pleural effusion was the first clinical manifestation. A 45-year-old man with dorsal pain presented with pleural thickening and effusion, and a visible nodule on a thoracic scan. A dense chronic inflammatory infiltrate was obtained by pleural biopsy and an open lung biopsy revealed necrotizing granulomatous vasculitis. Serologies were positive for antineutrophil cytoplasmic antibodies and antiproteinase 3 antibodies. A diagnosis of WG was conducted and the patient was started on cyclophosphamide and methylprednisolone as an initial treatment, with a favorable evolution. Although pleural effusion is rarely described in WG, this pathology must be considered in the presence of this clinical manifestation. PMID:20168982

  2. Wegener Granulomatosis Revealed by Pleural Effusion

    Directory of Open Access Journals (Sweden)

    Anne-Claire Toffart

    2009-01-01

    Full Text Available Pulmonary signs are common in Wegener's granulomatosis (WG. However, an initial presentation including pleural effusion has not been described. We describe a case of WG in which pleural effusion was the first clinical manifestation. A 45-year-old man with dorsal pain presented with pleural thickening and effusion, and a visible nodule on a thoracic scan. A dense chronic inflammatory infiltrate was obtained by pleural biopsy and an open lung biopsy revealed necrotizing granulomatous vasculitis. Serologies were positive for antineutrophil cytoplasmic antibodies and antiproteinase 3 antibodies. A diagnosis of WG was conducted and the patient was started on cyclophosphamide and methylprednisolone as an initial treatment, with a favorable evolution. Although pleural effusion is rarely described in WG, this pathology must be considered in the presence of this clinical manifestation.

  3. Revealing effective classifiers through network comparison

    Science.gov (United States)

    Gallos, Lazaros K.; Fefferman, Nina H.

    2014-11-01

    The ability to compare complex systems can provide new insight into the fundamental nature of the processes captured, in ways that are otherwise inaccessible to observation. Here, we introduce the n-tangle method to directly compare two networks for structural similarity, based on the distribution of edge density in network subgraphs. We demonstrate that this method can efficiently introduce comparative analysis into network science and opens the road for many new applications. For example, we show how the construction of a “phylogenetic tree” across animal taxa according to their social structure can reveal commonalities in the behavioral ecology of the populations, or how students create similar networks according to the University size. Our method can be expanded to study many additional properties, such as network classification, changes during time evolution, convergence of growth models, and detection of structural changes during damage.

  4. Fluorescent sensors reveal subcellular thermal changes.

    Science.gov (United States)

    Sakaguchi, Reiko; Kiyonaka, Shigeki; Mori, Yasuo

    2015-02-01

    In mammals and birds, thermoregulation to conserve body temperature is vital to life. Multiple mechanisms of thermogeneration have been proposed, localized in different subcellular organelles. However, studying thermogenesis directly in intact organelles has been challenging. Visualizing patterns of thermal changes at subcellular resolution would reveal physiologically relevant spatio-temporal information, especially if this could be done in the native cellular configuration of the cell. Here we review and compare the wide variety of intracellular thermosensors currently identified. This review focuses particularly on genetically encoded sensors. It also explores the notable physiological discoveries made using these imaging methods, which are rapidly becoming indispensible to the study of thermal biology. Copyright © 2014 Elsevier Ltd. All rights reserved.

  5. Ceres Revealed in a Grain of Salt

    Science.gov (United States)

    Zolensky, M. E.; Bodnar, R. J.; Fries, M.; Chan, Q. H.-S.; Kebukawa, Y.; Mikouchi, T.; Hagiya, K.; Komatsu, M.; Ohsumi, K.; Steele, A.

    2016-01-01

    Introduction: Zag and Monahans (1998) are H chondrite regolith breccias containing 4.5 giga-year-old halite crystals which contain abundant inclusions of aqueous fluids, solids and organics. These all originated on a cryo-volcanically-active C class asteroid, probably 1 Ceres; the halite was transported to the regolith of the H chondrite parent asteroid, potentially 6 Hebe. Detailed analysis of these solids will thus potentially reveal the mineralogy of Ceres. Mineralogy of solids in the Monahans Halite Solid grains are present in the halites, which were entrained within the mother brines during eruption, including material from the interior and surface of the erupting body. The solids include abundant, widely variable organics that could not have been significantly heated (which would have resulted in the loss of fluids from the halite). Our analyses by Raman microprobe, SEM/EDX, synchrotron X-ray diffraction, UPLC-FD/QToF-MS, C-XANES and TEM reveal that these trapped grains include macromolecular carbon (MMC) similar in structure to CV3 chondrite matrix carbon, aliphatic carbon compounds, olivine (Fo99-59), high- and low-Ca pyroxene, feldspars, phyllosilicates, magnetite, sulfides, metal, lepidocrocite, carbonates, diamond, apatite and zeolites. Conclusions: The halite in Monahans and Zag derive from a water and carbon-rich object that was cryo-volcanically active in the early solar system, probably Ceres. The Dawn spacecraft found that Ceres includes C chondrite materials. Our samples include both protolith and aqueously-altered samples of the body, permitting understanding of alteration conditions. Whatever the halite parent body, it was rich in a wide variety of organics and warm, liquid water at the solar system's dawn.

  6. Two thousand years of geomagnetic field direction over central Europe revealed by indirect measurements

    Science.gov (United States)

    Márton, Péter

    2010-04-01

    Supplemented by 32 new directions, the Hungarian archaeomagnetic data set now consists of 217 archaeologically dated directions ranging in age from 300 BC to 1800 AD. From this data set, reference curves of secular variation of the geomagnetic field direction were computed using hierarchical modelling and curve estimation by moving average technique. Thanks to some of the new data, the gap in the earlier reference curves around 500 AD has now been filled up. For comparison's sake, directional records of comparable length from central Europe were also processed by the same curve building method. For this purpose, all dated directional data (declination and inclination with statistics) were drawn from the GEOMAGIA50 database for France, Germany, the Ukraine and Moldavia, Bulgaria and Italy and transferred via their virtual geomagnetic poles to a reference point of their respective countries. The resulting reference curves, including those for Hungary, show more or less similar temporal behaviour to the corresponding CALS7K.2 model curves (also available from the GEOMAGIA50 database), but significant deviations from the low-order CALS7K.2 predictions are also discernible owing to the likely presence of additional higher-order complications in the regional field. Therefore, the regional field and its secular variation are suggested to be approximated by the reference rather than the predicted curves. At any other location within the study area, the direction of the regional field can be obtained by spatial interpolation from the reference curves as illustrated by isogonic and isoclinic maps shown for selected times. Local time-series of interpolated directions for other central European countries lacking reference curves might serve as master curves for magnetic dating.

  7. Variations of the global lightning distribution revealed from three-station Schumann resonance measurements

    Science.gov (United States)

    Shvets, A. V.; Hobara, Y.; Hayakawa, M.

    2010-12-01

    Schumann resonance (SR) observations performed simultaneously by a global network consisting of three stations (Lekhta (Karelia, Russia), Moshiri (Hokkaido, Japan), and West Greenwich (Rhode Island, United States)) during almost 1 year were used for mapping world thunderstorm activity. A two-stage inverse problem is solved for locating lightning sources distributed over the Earth's surface from the SR background signals. The first stage consists of inversions of the SR magnetic field power spectra to the distributions of lightning intensity by distance relative to an observation point. The obtained distance profiles of intensity of sources are used as tomographic projections for reconstructing a spatial distribution of sources in the second stage. We have suggested the use of source distance profiles obtained from the spectra of outputs of two orthogonal magnetic antennas operating at each observatory as separate tomographic projections. It is shown that the implementation of additional information on the azimuthal distribution of sources, provided by angular selectivity of magnetic sensors, significantly improves the quality of global lightning mapping under the condition of a limited number of observation stations. Maps of the global lightning distributions constructed by the result of inversions of SR spectra show that the most active regions vary zonally on the seasonal time scale and meridionally on the diurnal time scale being connected mainly with continental areas in the tropics.

  8. Using Regression to Measure Holistic Face Processing Reveals a Strong Link with Face Recognition Ability

    Science.gov (United States)

    DeGutis, Joseph; Wilmer, Jeremy; Mercado, Rogelio J.; Cohan, Sarah

    2013-01-01

    Although holistic processing is thought to underlie normal face recognition ability, widely discrepant reports have recently emerged about this link in an individual differences context. Progress in this domain may have been impeded by the widespread use of subtraction scores, which lack validity due to their contamination with control condition…

  9. Implicit and explicit measures: what their dissociations reveal about the workings of advertising

    NARCIS (Netherlands)

    Vandeberg, L.; Wennekers, A.M.; Murre, J.M.J.; Smit, E.G.; Verlegh, P.; Voorveld, H.; Eisend, M.

    2016-01-01

    Consider a scenario in which you participate in a study on advertising effects. You are instructed to attend to an advertisement, after which you are asked about your memory for the advertisement and advertised brand, your attitude towards the ad and brand, and your intention to purchase the

  10. Inhomogeneity of asteroid 2008 TC3 (Almahata Sitta meteorites) revealed through magnetic susceptibility measurements

    Czech Academy of Sciences Publication Activity Database

    Kohout, Tomáš; Jenniskens, P.; Shaddad, M.H.; Haloda, J.

    2010-01-01

    Roč. 45, 10/11 (2010), s. 1778-1788 ISSN 1086-9379 R&D Projects: GA AV ČR KJB300130903 Institutional research plan: CEZ:AV0Z30130516 Keywords : ureilite * magnetic susceptibility * Almahata Sitta * 2008 TC3 Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics Impact factor: 2.624, year: 2010

  11. Inhomogeneity of the 2008 TC3 asteroid (Almahata Sitta meteorites) revealed through physical properties measurements

    Czech Academy of Sciences Publication Activity Database

    Kohout, Tomáš; Jenniskens, P.; Haloda, J.; Britt, D.

    2010-01-01

    Roč. 45, Suppl. S (2010), s. 5046-5046 ISSN 1086-9379. [Annual Meeting of the Meteoritical Society /73./. 26.07.2010-30.07.2010, New York] Institutional research plan: CEZ:AV0Z30130516 Keywords : Almahata Sitta * 2008 TC3 * physical properties Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics http://www.lpi.usra.edu/meetings/metsoc2010/pdf/sess151.pdf

  12. High precision isotope measurements reveal poor control of copper metabolism in parkinsonism.

    Science.gov (United States)

    Larner, F; Sampson, B; Rehkämper, M; Weiss, D J; Dainty, J R; O'Riordan, S; Panetta, T; Bain, P G

    2013-02-01

    Disordered copper metabolism may be important in the aetiology of Parkinsonism, as caeruloplasmin is a key enzyme in handling oxidative stress and is involved in the synthesis pathway of dopamine. The human Cu metabolism of ten Parkinsonism patients was compared to ten healthy controls with the aid of a stable (65)Cu isotope tracer. The analyses of blood serum (65)Cu/(63)Cu ratios yielded individual isotopic profiles, which indicate that the Cu metabolism is less controlled in patients with Parkinsonism. Modelling based on both isotope tracer and total Cu concentrations suggests that 30% of the subjects affected by Parkinsonism have abnormally large Cu stores in tissues. To detect the small differences in Cu metabolism between Parkinsonism and controls, the analysis of stable isotope composition must be performed using multiple-collector inductively coupled plasma mass spectrometry and the associated sample preparation techniques. This pilot investigation supports full-scale medical studies into the Cu metabolism of those with Parkinsonism.

  13. Leaf aging of Amazonian canopy trees as revealed by spectral and physiochemical measurements.

    Science.gov (United States)

    Chavana-Bryant, Cecilia; Malhi, Yadvinder; Wu, Jin; Asner, Gregory P; Anastasiou, Athanasios; Enquist, Brian J; Cosio Caravasi, Eric G; Doughty, Christopher E; Saleska, Scott R; Martin, Roberta E; Gerard, France F

    2017-05-01

    Leaf aging is a fundamental driver of changes in leaf traits, thereby regulating ecosystem processes and remotely sensed canopy dynamics. We explore leaf reflectance as a tool to monitor leaf age and develop a spectra-based partial least squares regression (PLSR) model to predict age using data from a phenological study of 1099 leaves from 12 lowland Amazonian canopy trees in southern Peru. Results demonstrated monotonic decreases in leaf water (LWC) and phosphorus (P mass ) contents and an increase in leaf mass per unit area (LMA) with age across trees; leaf nitrogen (N mass ) and carbon (C mass ) contents showed monotonic but tree-specific age responses. We observed large age-related variation in leaf spectra across trees. A spectra-based model was more accurate in predicting leaf age (R 2  = 0.86; percent root mean square error (%RMSE) = 33) compared with trait-based models using single (R 2  = 0.07-0.73; %RMSE = 7-38) and multiple (R 2  = 0.76; %RMSE = 28) predictors. Spectra- and trait-based models established a physiochemical basis for the spectral age model. Vegetation indices (VIs) including the normalized difference vegetation index (NDVI), enhanced vegetation index 2 (EVI2), normalized difference water index (NDWI) and photosynthetic reflectance index (PRI) were all age-dependent. This study highlights the importance of leaf age as a mediator of leaf traits, provides evidence of age-related leaf reflectance changes that have important impacts on VIs used to monitor canopy dynamics and productivity and proposes a new approach to predicting and monitoring leaf age with important implications for remote sensing. © 2016 The Authors. New Phytologist © 2016 New Phytologist Trust.

  14. Measuring Absolute RNA Copy Numbers at High Temporal Resolution Reveals Transcriptome Kinetics in Development

    Directory of Open Access Journals (Sweden)

    Nick D.L. Owens

    2016-01-01

    Full Text Available Transcript regulation is essential for cell function, and misregulation can lead to disease. Despite technologies to survey the transcriptome, we lack a comprehensive understanding of transcript kinetics, which limits quantitative biology. This is an acute challenge in embryonic development, where rapid changes in gene expression dictate cell fate decisions. By ultra-high-frequency sampling of Xenopus embryos and absolute normalization of sequence reads, we present smooth gene expression trajectories in absolute transcript numbers. During a developmental period approximating the first 8 weeks of human gestation, transcript kinetics vary by eight orders of magnitude. Ordering genes by expression dynamics, we find that “temporal synexpression” predicts common gene function. Remarkably, a single parameter, the characteristic timescale, can classify transcript kinetics globally and distinguish genes regulating development from those involved in cellular metabolism. Overall, our analysis provides unprecedented insight into the reorganization of maternal and embryonic transcripts and redefines our ability to perform quantitative biology.

  15. DXA measurements in Rett syndrome reveal small bones with low bone mass.

    Science.gov (United States)

    Roende, Gitte; Ravn, Kirstine; Fuglsang, Kathrine; Andersen, Henrik; Nielsen, Jytte Bieber; Brøndum-Nielsen, Karen; Jensen, Jens-Erik Beck

    2011-09-01

    Low bone mass is reported in growth-retarded patients harboring mutations in the X-linked methyl-CpG-binding protein 2 (MECP2) gene causing Rett syndrome (RTT). We present the first study addressing both bone mineral density (BMD) and bone size in RTT. Our object was to determine whether patients with RTT do have low BMD when correcting for smaller bones by examination with dual-energy X-ray absorptiometry (DXA). We compared areal BMD (aBMD(spine) and aBMD(total hip) ) and volumetric bone mineral apparent density (vBMAD(spine) and vBMAD(neck) ) in 61 patients and 122 matched healthy controls. Further, spine and hip aBMD and vBMAD of patients were associated with clinical risk factors of low BMD, low-energy fractures, MECP2 mutation groups, and X chromosome inactivation (XCI). Patients with RTT had reduced bone size on the order of 10% and showed lower values of spine and hip aBMD and vBMAD (p bone mass and small bones are evident in RTT, indicating an apparent low-bone-formation phenotype. Copyright © 2011 American Society for Bone and Mineral Research.

  16. DXA measurements in rett syndrome reveal small bones with low bone mass

    DEFF Research Database (Denmark)

    Roende, Gitte; Ravn, Kirstine; Fuglsang, Kathrine

    2011-01-01

    Low bone mass is reported in growth-retarded patients harboring mutations in the X-linked methyl-CpG-binding protein 2 (MECP2) gene causing Rett syndrome (RTT). We present the first study addressing both bone mineral density (BMD) and bone size in RTT. Our object was to determine whether patients...

  17. Torque measurements reveal large process differences between materials during high solid enzymatic hydrolysis of pretreated lignocellulose

    Directory of Open Access Journals (Sweden)

    Palmqvist Benny

    2012-08-01

    Full Text Available Abstract Background A common trend in the research on 2nd generation bioethanol is the focus on intensifying the process and increasing the concentration of water insoluble solids (WIS throughout the process. However, increasing the WIS content is not without problems. For example, the viscosity of pretreated lignocellulosic materials is known to increase drastically with increasing WIS content. Further, at elevated viscosities, problems arise related to poor mixing of the material, such as poor distribution of the enzymes and/or difficulties with temperature and pH control, which results in possible yield reduction. Achieving good mixing is unfortunately not without cost, since the power requirements needed to operate the impeller at high viscosities can be substantial. This highly important scale-up problem can easily be overlooked. Results In this work, we monitor the impeller torque (and hence power input in a stirred tank reactor throughout high solid enzymatic hydrolysis (Arundo donax and spruce. Two different process modes were evaluated, where either the impeller speed or the impeller power input was kept constant. Results from hydrolysis experiments at a fixed impeller speed of 10 rpm show that a very rapid decrease in impeller torque is experienced during hydrolysis of pretreated arundo (i.e. it loses its fiber network strength, whereas the fiber strength is retained for a longer time within the spruce material. This translates into a relatively low, rather WIS independent, energy input for arundo whereas the stirring power demand for spruce is substantially larger and quite WIS dependent. By operating the impeller at a constant power input (instead of a constant impeller speed it is shown that power input greatly affects the glucose yield of pretreated spruce whereas the hydrolysis of arundo seems unaffected. Conclusions The results clearly highlight the large differences between the arundo and spruce materials, both in terms of needed energy input, and glucose yields. The impact of power input on glucose yield is furthermore shown to vary significantly between the materials, with spruce being very affected while arundo is not. These findings emphasize the need for substrate specific process solutions, where a short pre-hydrolysis (or viscosity reduction might be favorable for arundo whereas fed-batch might be a better solution for spruce.

  18. New Insight of Northern Apennines (Italy): SKS Splitting Measurements Reveal a Complex Anisotropic Structure

    Science.gov (United States)

    Salimbeni, S.; Pondrelli, S.; Margheriti, L.; Levin, V.; Park, J.; Plomerova, J.

    2006-12-01

    The multidisciplinary RETREAT project (REtreating-Trench, Extension and Accretion Tectonics) is focused on the development of a 3D self-consistent dynamic model of the syn-convergent extension in the Northern Apennines. The seismological deployment of the Project started on 2003 and closed on September 2006, using 10 instruments lent by the GFU and 25 instruments lent by PASSCAL, added to the permanent stations of the Italian National Network. Many of the stations were deployed along a NE-SW transect across the Apennine chain. We present here new results of seismic anisotropy analysis obtained from SKS core-refracted shear waves. The study of SKS splitting is applied on twenty teleseismic earthquakes; for all of them we calculate the anisotropic parameters (delay time and fast polarization direction) by minimizing the energy in the transverse component. Our analysis assesses uncertainty by testing the parameters for stability to noise. Previous studies of splitting analysis have found in the study region evidence for tectonic domains in which a coherent splitting signal can be found. The Tuscany domain (Tyrrhenian side) shows homogeneous NW-SE fast axes directions; the Po-Plain domain (Eastern side of the Apennines) shows a N-S to NE-SW directions, here strongly influenced by backazimuth. To better define the complex structure that may exist below the Northern Apennines and Po Plain we apply the cross convolution method of Menke and Levin (2003) to discriminate whether a two-layer anisotropic model fits the splitting pattern more convincingly that a simple one-layer model. Previous analysis suggested that structure beneath the Tuscany side is simpler; a single anisotropic layer with a NW-SE fast polarization direction is in agreement with all the dataset. Beneath the Po Plain the complexity of the structure is confirmed in the analysis of most stations.

  19. Robust dynamic classes revealed by measuring the response function of a social system.

    Science.gov (United States)

    Crane, Riley; Sornette, Didier

    2008-10-14

    We study the relaxation response of a social system after endogenous and exogenous bursts of activity using the time series of daily views for nearly 5 million videos on YouTube. We find that most activity can be described accurately as a Poisson process. However, we also find hundreds of thousands of examples in which a burst of activity is followed by an ubiquitous power-law relaxation governing the timing of views. We find that these relaxation exponents cluster into three distinct classes and allow for the classification of collective human dynamics. This is consistent with an epidemic model on a social network containing two ingredients: a power-law distribution of waiting times between cause and action and an epidemic cascade of actions becoming the cause of future actions. This model is a conceptual extension of the fluctuation-dissipation theorem to social systems [Ruelle, D (2004) Phys Today 57:48-53] and [Roehner BM, et al., (2004) Int J Mod Phys C 15:809-834], and provides a unique framework for the investigation of timing in complex systems.

  20. Measuring phase with Stokes measurements

    CSIR Research Space (South Africa)

    Dudley, Angela L

    2014-07-01

    Full Text Available Measurements Angela Dudley1, Giovanni Milione2, Robert Alfano2 and Andrew Forbes1. 1 CSIR National Laser Centre, Pretoria, South Africa. 2 Institute for Ultrafast Spectroscopy and Lasers, Physics Department, City College of New York,160 Convent Ave., New... polarimetry I45° IR I135° IL S2 S3 tan-1 S2 S3 * : Control the phase between & Stokes polarimetry involves four separate measurements * Independently control the phase between & Requirements for a digital adaptation of Stokes polarimetery: 45° I45° U...

  1. Measuring Segregation

    OpenAIRE

    Oscar Volij; David Frankel

    2004-01-01

    We propose a set of axioms for the measurement of multigroup school segregation. They are motivated by two criteria: do ethnic groups have similar distributions across schools? And are schools ethnically representative of their district? Our axioms are satisfied by a unique ordering. It is represented by the Mutual Information index. This index, originally proposed by Henri Theil, has a more intuitive decomposition than other indices. As an application, we find that segregation between distri...

  2. Measurement of very rapidly variable temperatures

    International Nuclear Information System (INIS)

    Elberg, S.; Mathonnet, P.

    1974-01-01

    Bibliographical research and visits to laboratories were undertaken in order to survey the different techniques used to measure rapidly variable temperatures, specifying the limits in maximum temperature and variation rate (time constant). On the basis of the bibliographical study these techniques were classified in three categories according to the physical meaning of their response time. Extension of the bibliographical research to methods using fast temperature variation measurement techniques and visits to research and industrial laboratories gave in an idea of the problems raised by the application of these methods. The use of these techniques in fields other than those for which they were developed can sometimes be awkward in the case of thermometric probe devices where the time constant cannot generally be specified [fr

  3. When Measurement Benefits the Measured

    Science.gov (United States)

    2014-04-23

    TSP Mentor Coach and a certified Scrum Master. Report Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting burden for the collection of...groups than they have today. Capers Jones InfoQ Interview March 30, 2014 http://www.infoq.com/articles/Jones-measuring- agile -adoption Can

  4. Speeding Clouds May Reveal Invisible Black Holes

    Science.gov (United States)

    Kohler, Susanna

    2017-07-01

    Several small, speeding clouds have been discovered at the center of our galaxy. A new study suggests that these unusual objects may reveal the lurking presence of inactive black holes.Peculiar Cloudsa) Velocity-integrated intensity map showing the location of the two high-velocity compact clouds, HCN0.0090.044 and HCN0.0850.094, in the context of larger molecular clouds. b) and c) Latitude-velocity and longitude-velocity maps for HCN0.0090.044 and HCN0.0850.094, respectively. d) and e) spectra for the two compacts clouds, respectively. Click for a closer look. [Takekawa et al. 2017]Sgr A*, the supermassive black hole marking the center of our galaxy, is surrounded by a region roughly 650 light-years across known as the Central Molecular Zone. This area at the heart of our galaxy is filled with large amounts of warm, dense molecular gas that has a complex distribution and turbulent kinematics.Several peculiar gas clouds have been discovered within the Central Molecular Zone within the past two decades. These clouds, dubbed high-velocity compact clouds, are characterized by their compact sizes and extremely broad velocity widths.What created this mysterious population of energetic clouds? The recent discovery of two new high-velocity compact clouds, reported on in a paper led by Shunya Takekawa (Keio University, Japan), may help us to answer this question.Two More to the CountUsing the James Clerk Maxwell Telescope in Hawaii, Takekawa and collaborators detected the small clouds near the circumnuclear disk at the centermost part of our galaxy. These two clouds have velocity spreads of -80 to -20 km/s and -80 to 0 km/s and compact sizes of just over 1 light-year. The clouds similar appearances and physical properties suggest that they may both have been formed by the same process.Takekawa and collaborators explore and discard several possible origins for these clouds, such as outflows from massive protostars (no massive, luminous stars have been detected affiliated

  5. Covert waking brain activity reveals instantaneous sleep depth.

    Directory of Open Access Journals (Sweden)

    Scott M McKinney

    Full Text Available The neural correlates of the wake-sleep continuum remain incompletely understood, limiting the development of adaptive drug delivery systems for promoting sleep maintenance. The most useful measure for resolving early positions along this continuum is the alpha oscillation, an 8-13 Hz electroencephalographic rhythm prominent over posterior scalp locations. The brain activation signature of wakefulness, alpha expression discloses immediate levels of alertness and dissipates in concert with fading awareness as sleep begins. This brain activity pattern, however, is largely ignored once sleep begins. Here we show that the intensity of spectral power in the alpha band actually continues to disclose instantaneous responsiveness to noise--a measure of sleep depth--throughout a night of sleep. By systematically challenging sleep with realistic and varied acoustic disruption, we found that sleepers exhibited markedly greater sensitivity to sounds during moments of elevated alpha expression. This result demonstrates that alpha power is not a binary marker of the transition between sleep and wakefulness, but carries rich information about immediate sleep stability. Further, it shows that an empirical and ecologically relevant form of sleep depth is revealed in real-time by EEG spectral content in the alpha band, a measure that affords prediction on the order of minutes. This signal, which transcends the boundaries of classical sleep stages, could potentially be used for real-time feedback to novel, adaptive drug delivery systems for inducing sleep.

  6. Neutron Imaging Reveals Internal Plant Hydraulic Dynamics

    Science.gov (United States)

    Warren, J.; Bilheux, H.; Kang, M.; Voisin, S.; Cheng, C.; Horita, J.; Perfect, E.

    2011-12-01

    In situ quantification of soil-plant water fluxes have not been fully successful due to a lack of non-destructive techniques capable of revealing roots or water fluxes at relevant spatial scales. Neutron imaging is a unique non-invasive tool that can assess sub-millimeter scale material properties and transport in situ, and which has been successfully applied to characterize soil and plant water status. Here, we have applied neutron radiography and tomography to quantify water transport through individual maize roots in response to internal plant demand. Zea mays seedlings were grown for 10 days in Flint silica sand within 2.6 cm diameter Al chambers. Using a reactor-based neutron source at Oak Ridge National Laboratory (HFIR), water fluxes were tracked through the maize soil-root systems by collecting consecutive neutron radiographs over a 12 h period following irrigation with D2O. D has a much lower neutron attenuation than H, thus D2O displacement of existing H2O within the plant vascular system, or influx of D2O into previously dry tissue or soil is readily tracked by changes in image intensity through time. Plant water release and uptake was regulated by periodically cycling on a high-intensity grow light. From each maize replicate, selected regions of interest (ROI) were delineated around individual roots, root free soil, stem and leaf segments. Changes in ROI were tracked through time to reveal patterns of water flux. The hydration of root and stem tissue cycled in response to illumination; root water content often increased during darkness, then decreased with illumination as water was transported from the root into the stem. Relative root-shoot hydration through time illustrates the balance between demand, storage capacity and uptake, which varies depending on root characteristics and its localized soil environment. The dynamic transport of water between soil, individual roots, stems and leaves was readily visualized and quantified illustrating the value

  7. Conceptual measurement framework for help-seeking for mental health problems

    Directory of Open Access Journals (Sweden)

    Rickwood D

    2012-12-01

    Full Text Available Debra Rickwood, Kerry ThomasFaculty of Health, University of Canberra, ACT, AustraliaBackground: Despite a high level of research, policy, and practice interest in help-seeking for mental health problems and mental disorders, there is currently no agreed and commonly used definition or conceptual measurement framework for help-seeking.Methods: A systematic review of research activity in the field was undertaken to investigate how help-seeking has been conceptualized and measured. Common elements were used to develop a proposed conceptual measurement framework.Results: The database search revealed a very high level of research activity and confirmed that there is no commonly applied definition of help-seeking and no psychometrically sound measures that are routinely used. The most common element in the help-seeking research was a focus on formal help-seeking sources, rather than informal sources, although studies did not assess a consistent set of professional sources; rather, each study addressed an idiosyncratic range of sources of professional health and community care. Similarly, the studies considered help-seeking for a range of mental health problems and no consistent terminology was applied. The most common mental health problem investigated was depression, followed by use of generic terms, such as mental health problem, psychological distress, or emotional problem. Major gaps in the consistent measurement of help-seeking were identified.Conclusion: It is evident that an agreed definition that supports the comparable measurement of help-seeking is lacking. Therefore, a conceptual measurement framework is proposed to fill this gap. The framework maintains that the essential elements for measurement are: the part of the help-seeking process to be investigated and respective time frame, the source and type of assistance, and the type of mental health concern. It is argued that adopting this framework will facilitate progress in the field by

  8. Comparison of orthodontic measurements on dental plaster casts and 3D scans.

    Science.gov (United States)

    Radeke, Johanna; von der Wense, Cynthia; Lapatki, Bernd G

    2014-07-01

    Over recent years, we have witnessed a growing trend in orthodontics toward the use of three-dimensional (3D) techniques for diagnostic purposes, treatment planning, and fabricating appliances. This study was undertaken to compare the traditional manual technique of using vernier calipers to take orthodontic measurements on plaster dental casts versus an all-digital measuring technique based on virtual 3D scans of casts. In this study, we focused on the quantitative agreement between and time requirements of both methods. Plaster casts obtained from the jaws of 55 fully dentate patients who had not previously undergone orthodontic treatment underwent 3D scanning using a white-light scanner (d-Station (3D); Breuckmann, Meersburg, Germany). Once the casts had been blinded by an independent individual, three examiners with different degrees of expertise in dentistry and orthodontics measured the mesiodistal widths of teeth 6-6 in each jaw. A randomized sequence was used when taking the measurements three times using OnyxCeph(3TM) analysis software (Image Instruments, Chemnitz, Germany) and a dental vernier caliper. Bland-Altman plots were used to illustrate the level of agreement between the two methods, standard deviations of repeated measurements were calculated to assess their reproducibility, and the Wilcoxon's signed-rank test was employed to compare their time requirements. The Bland-Altman analysis of all single values revealed no statistically significant difference between the software-based and caliper-based measurements of mesiodistal tooth width. Assuming the presence of normal distribution, the limits of agreement disclosed a 95% probability for the software values to range between +0.499 and -0.545 mm of the same value measured with the caliper. The standard deviations of repeated measurements were 0.33 mm with the software and 0.21 mm with the caliper. The digital method required significantly less time (p<0.01); however, differences were observed to be

  9. Measuring and Ranking Value Drivers

    NARCIS (Netherlands)

    M.M. Akalu

    2002-01-01

    textabstractAnalysis of the strength of value drivers is crucial to understand their influence in the process of free cash flow generation. The paper addresses the issue of value driver measurement and ranking. The research reveals that, value drivers have similar pattern across industries.

  10. Revealing water's secrets: deuterium depleted water.

    Science.gov (United States)

    Goncharuk, Vladyslav V; Kavitskaya, Alina A; Romanyukina, Iryna Yu; Loboda, Oleksandr A

    2013-06-17

    The anomalous properties of water have been of great interest for generations of scientists. However the impact of small amount of deuterium content which is always present in water has never been explored before. For the first time the fundamental properties of deuterium depleted (light) water at 4°C and 20°C are here presented. The obtained results show the important role of the deuterium in the properties of bulk water. At 4°C the lowest value of the kinematic viscosity (1.46 mm2/s) has been found for 96.5 ppm D/H ratio. The significant deviation in surface tension values has been observed in deuterium depleted water samples at the both temperature regimes. The experimental data provides direct evidence that density, surface tension and viscosity anomalies of water are caused by the presence of variable concentration of deuterium which leads to the formation of water clusters of different size and quantity. The investigated properties of light water reveal the origin of the water anomalies. The new theoretical model of cluster formation with account of isotope effect is proposed.

  11. VISTA Reveals the Secret of the Unicorn

    Science.gov (United States)

    2010-10-01

    A new infrared image from ESO's VISTA survey telescope reveals an extraordinary landscape of glowing tendrils of gas, dark clouds and young stars within the constellation of Monoceros (the Unicorn). This star-forming region, known as Monoceros R2, is embedded within a huge dark cloud. The region is almost completely obscured by interstellar dust when viewed in visible light, but is spectacular in the infrared. An active stellar nursery lies hidden inside a massive dark cloud rich in molecules and dust in the constellation of Monoceros. Although it appears close in the sky to the more familiar Orion Nebula it is actually almost twice as far from Earth, at a distance of about 2700 light-years. In visible light a grouping of massive hot stars creates a beautiful collection of reflection nebulae where the bluish starlight is scattered from parts of the dark, foggy outer layers of the molecular cloud. However, most of the new-born massive stars remain hidden as the thick interstellar dust strongly absorbs their ultraviolet and visible light. In this gorgeous infrared image taken from ESO's Paranal Observatory in northern Chile, the Visible and Infrared Survey Telescope for Astronomy (VISTA [1], eso0949) penetrates the dark curtain of cosmic dust and reveals in astonishing detail the folds, loops and filaments sculpted from the dusty interstellar matter by intense particle winds and the radiation emitted by hot young stars. "When I first saw this image I just said 'Wow!' I was amazed to see all the dust streamers so clearly around the Monoceros R2 cluster, as well as the jets from highly embedded young stellar objects. There is such a great wealth of exciting detail revealed in these VISTA images," says Jim Emerson, of Queen Mary, University of London and leader of the VISTA consortium. With its huge field of view, large mirror and sensitive camera, VISTA is ideal for obtaining deep, high quality infrared images of large areas of the sky, such as the Monoceros R2 region

  12. Myasthenia Revealed Following Laparotomy - A Case Report

    Directory of Open Access Journals (Sweden)

    Abdelilah GHANNAM

    2015-06-01

    Full Text Available Myasthenia (muscle weakness is a rare neuromuscular disease of which respiratory failure is the main complication. The accidental discovery of such disease in the perioperative period is rare and potentially serious.We report a case of a woman who underwent emergency operation for appendiceal peritonitis, and failed repeatedly at weaning from postoperative mechanical ventilation. The usual etiologies such as postoperative respiratory complications, ventilator-associated pneumonia, acute respiratory distress syndrome complicating the septic shock or having no impact on it, and neuromyopathy’s resuscitation were considered, researched, examined or eliminated.Faced with the diagnostic impasse and the obvious weaning failure, another interview revealed signs of muscle fatigue which led to the diagnosis of myasthenia gravis decompensated perioperatively. Once the diagnosis was confirmed by means of a neostigmine test, the specific treatment began, particularly through plasma exchange sessions, and the process of weaning resumed. The result was complete weaning. A three-month follow-up showed a stable patient with no significant muscular disability.

  13. Revealing the values behind convenience food consumption.

    Science.gov (United States)

    Botonaki, Anna; Mattas, Konstadinos

    2010-12-01

    The increasing importance of convenience in consumer food choices has attracted researchers' interest. In the effort to understand how convenience affects consumers' food preferences, values are believed to play an important role. The present study attempts to examine the way personal values suggested by Schwartz (1992) are associated with behaviour and attitudes regarding convenience food. A number of constructs describing food related attitudes and behaviours were developed and their relationship with personal values was analyzed following the methodology proposed by Brunsø, Scholderer, and Grunert (2004). Data were collected through a questionnaire survey from a random sample of consumers in Thessaloniki city, Greece. The results reveal that convenience food consumption and convenience orientation in the food domain are mainly connected with values that motivate people to seek new experiences, act independently and enhance their own personal interests, while are in conflict with values of conservation and self-transcendence. The opposite holds for other food related attitudes and behaviours like involvement with cooking and variety in diet. The findings seem to be of particular interest not only for marketers of food products, but also for food policy makers. Copyright © 2010 Elsevier Ltd. All rights reserved.

  14. ERYTHEMA NODOSUM REVEALING ACUTE MYELOID LEUKEMIA

    Directory of Open Access Journals (Sweden)

    Chebbi Wafa

    2013-07-01

    Full Text Available Introduction: Erythema nodosum (EN is the most common type of panniculitis. It may be idiopathic or secondary to various etiologies. However, the occurrence of erythema nodosum in malignant hemopathy had rarely been reported. Case report: A 42 year-old woman presented with a four week history of recurrent multiple painful erythematous nodules developed on the lower limbs associated with arthralgia of the ankles and fever. The clinical features of skin lesions with contusiform color evolution allowed establishing the diagnosis of EN. No underlying cause was found. The skin lesions were improved with non-steroidal anti-inflammatory drugs and colchicine. Three months later, the patient consulted for recurrence of EN associated with fever, inflammatory polyarthralgia and hepatosplenomegaly. The peripheral blood count revealed pancytopenia. A bone marrow examination confirmed the diagnosis of acute myeloid leukemia type 2. Initiation of chemotherapy was followed by the complete disappearance of skin lesions of EN. Conclusion: Paraneoplastic erythema nodosum is a rare entity. In the literature, a few cases of association with leukemia have been reported. Exploration for solid neoplasms or hemopathy in case of recurrent EN or resistance to conventional treatment should be systematic

  15. Featured Image: Revealing Hidden Objects with Color

    Science.gov (United States)

    Kohler, Susanna

    2018-02-01

    Stunning color astronomical images can often be the motivation for astronomers to continue slogging through countless data files, calculations, and simulations as we seek to understand the mysteries of the universe. But sometimes the stunning images can, themselves, be the source of scientific discovery. This is the case with the below image of Lynds Dark Nebula 673, located in the Aquila constellation, that was captured with the Mayall 4-meter telescope at Kitt Peak National Observatory by a team of scientists led by Travis Rector (University of Alaska Anchorage). After creating the image with a novel color-composite imaging method that reveals faint H emission (visible in red in both images here), Rector and collaborators identified the presence of a dozen new Herbig-Haro objects small cloud patches that are caused when material is energetically flung out from newly born stars. The image adapted above shows three of the new objects, HH 118789, aligned with two previously known objects, HH 32 and 332 suggesting they are driven by the same source. For more beautiful images and insight into the authors discoveries, check out the article linked below!Full view of Lynds Dark Nebula 673. Click for the larger view this beautiful composite image deserves! [T.A. Rector (University of Alaska Anchorage) and H. Schweiker (WIYN and NOAO/AURA/NSF)]CitationT. A. Rector et al 2018 ApJ 852 13. doi:10.3847/1538-4357/aa9ce1

  16. High-frequency microrheology reveals cytoskeleton dynamics in living cells

    Science.gov (United States)

    Rigato, Annafrancesca; Miyagi, Atsushi; Scheuring, Simon; Rico, Felix

    2017-08-01

    Living cells are viscoelastic materials, dominated by an elastic response on timescales longer than a millisecond. On shorter timescales, the dynamics of individual cytoskeleton filaments are expected to emerge, but active microrheology measurements on cells accessing this regime are scarce. Here, we develop high-frequency microrheology experiments to probe the viscoelastic response of living cells from 1 Hz to 100 kHz. We report the viscoelasticity of different cell types under cytoskeletal drug treatments. On previously inaccessible short timescales, cells exhibit rich viscoelastic responses that depend on the state of the cytoskeleton. Benign and malignant cancer cells revealed remarkably different scaling laws at high frequencies, providing a unique mechanical fingerprint. Microrheology over a wide dynamic range--up to the frequency characterizing the molecular components--provides a mechanistic understanding of cell mechanics.

  17. Statistical measures of unsustainability

    International Nuclear Information System (INIS)

    Ayres, Robert U.

    1996-01-01

    Statistical measures are needed to reveal at a glance how far (or near) various countries are to meeting the conditions of long-run sustainability, and how conditions are changing on a year-to-year basis (i.e., whether sustainability is being approached or not). The scheme proposed in this paper presents numerical comparisons of energy and materials use in the real world vis a vis an ideal case where all of the identifiable criteria for sustainability are satisfied. Apart from population stabilization, five general but quantifiable criteria for sustainability are suggested, including (1) stabilization of greenhouse gas concentrations in the atmosphere, (2) stabilization of acidity (pH) in rainfall, (3) reduction of dissipative uses, and wastes, of heavy metals to natural mobilization rates, or lower, (4) elimination of agriculture based on pumping 'fossil' water from non-renewable aquifers and (5) elimination of loss of arable land because of salination or erosion. Other criteria, such as preservation of biodiversity and socio-economic equity between countries and generations might be added to the list. They introduce more difficult measurement problems, however, which are not considered further in the paper. Having fixed the list of criteria, the next step is to identify measures that either go to zero or unity, as the system approaches more and more closely to sustainability, at least in the limited sense defined above. Various types of measures of sustainability/unsustainability can be developed, viz. (1) measures of relative dependence of the economy on non-renewable sources of energy and materials, (2) measures of the productivity of energy and materials consumed by the economic system and (3) measures of dissipative loss, especially of toxic and hazardous substances. Specific examples of each type are discussed

  18. Eye movement monitoring reveals differential influences of emotion on memory

    Directory of Open Access Journals (Sweden)

    Lily Riggs

    2010-11-01

    Full Text Available Research shows that memory for emotional aspects of an event may be enhanced at the cost of impaired memory for surrounding peripheral details. However, this has only been assessed directly via verbal reports which reveal the outcome of a long stream of processing but cannot shed light on how/when emotion may affect the retrieval process. In the present experiment, eye movement monitoring was used as an indirect measure of memory as it can reveal aspects of online memory processing. For example, do emotions modulate the nature of memory representations or the speed with which such memories can be accessed? Participants viewed central negative and neutral scenes surrounded by three neutral objects and after a brief delay, memory was assessed indirectly via eye movement monitoring and then directly via verbal reports. Consistent with the previous literature, emotion enhanced central and impaired peripheral memory as indexed by eye movement scanning and verbal reports. This suggests that eye movement scanning may contribute and/or is related to conscious access of memory. However, the central/peripheral tradeoff effect was not observed in an early measure of eye movement behavior, i.e. participants were faster to orient to a critical region of change in the periphery irrespective of whether it was previously studied in a negative or neutral context. These findings demonstrate emotion’s differential influences on different aspects of retrieval. In particular, emotion appears to affect the detail within, and/or the evaluation of, stored memory representations, but it may not affect the initial access to those representations.

  19. Actions undertaken in order to solve the tube guide pins cracking

    International Nuclear Information System (INIS)

    Benhamou, C.; Briois, J.P.; Tuncer, T.; Drean, H.

    1985-01-01

    Short-term actions have been developed after the discovery of defects on the guide tube pins (upper internal rector components) of 21 units in France. The impact analysis of a pin failure on the safety by Framatome show that short-term consequences are not very important. Improvements in regard with the design and the stress corrosion resistance of the material, which can be applied to the pins, have been defined. Framatome and EDF developed tools and the mastery of replacement operations what led to limit considerably the unavailability of units; 17 units have been treated for two years and half; the four last ones will be treated in 1985. Parallel studies allow to estimate the available marge of in-service behavior of the replacement pins; this marge is increased in units which are built now by means of new developments concerning the design and the mounting conditions. A method and tools utilizing ultrasonic waves have been developed for on-site inspection of the pins [fr

  20. LCA as a Tool for Assessing Product and Process Oriented Eco-Innovations Undertaken by Enterprises

    Directory of Open Access Journals (Sweden)

    Rybaczewska-Błażejowska Magdalena

    2017-09-01

    Full Text Available This paper examines the application of life cycle assessment (LCA as an approach to foster the product and process oriented eco- innovation of enterprises, using the fruit and vegetable processing plant as an example. LCA, which is traditionally used to assess the impacts of a single product system on the environment, was applied in the enterprise context. This was made possible by forming an indicator describing the environmental profile of an enterprise, which is calculated by the sum of the multiplication of the environmental impact assessment (LCIA results for individual unit processes within a particular impact category and their weights reflecting the structure of production in an enterprise. In order to distinguish and indicate the direction in which an enterprise should undertake its eco-innovative actions (implementing eco-innovations within the product or production process the LCIA results are presented individually for products and production processes. The research was conducted in full compliance with the LCA methodology. LCA proved that the analysed enterprise has the largest negative impacts on the environment in the following impact categories: marine eco-toxicity, freshwater eco-toxicity, freshwater eutrophication, human toxicity and natural land transformation. They result primarily from the consumption of thermal and electric energy in the production processes. Therefore, to improve energy efficiency, the enterprise should take eco-innovative actions in the processes applied.

  1. Hazard of household cleaning products: a study undertaken by the UK National Poisons Information Service.

    Science.gov (United States)

    Williams, Hayley; Moyns, Emma; Bateman, D Nicholas; Thomas, Simon H L; Thompson, John P; Vale, J Allister

    2012-09-01

    To ascertain the reported toxicity of current United Kingdom (UK) household products following the launch of new products, such as liquid detergent capsules, and the manufacture of more concentrated formulations. Between 1 March 2008 and 30 April 2009 the UK National Poisons Information Service (NPIS) collected prospectively 5939 telephone enquiries relating to household products, approximately 10% of all telephone enquiries received over this period. The majority of enquiries (n = 3893; 65.5%) concerned children 5 years of age or less and were received predominantly from hospitals (n = 1905; 32.1%), general practitioners (n = 1768; 29.8%) and NHS Direct/NHS 24 (n = 1694; 28.5%). The majority of exposures occurred at home (n = 5795; 97.6%); most exposures were accidental (n = 5561; 93.6%). Liquid detergent capsules were most commonly involved (n = 647), followed by bleaches (n = 481), air fresheners (n = 429), multipurpose cleaners (n = 408), dishwasher products (n = 399) and descalers (n = 397). Exposure to household products occurred mainly as a result of ingestion (n = 4616; 75.8%), with eye contact (n = 513; 8.4%), inhalation (n = 420; 6.9%) and skin contact (n = 187; 3.1%) being less common; 5.1% (n = 313) of enquiries involved multiple routes of exposure. The most commonly reported features were vomiting (ingestion), pain (eye contact), dyspnoea (inhalation) and burns (skin contact). In 5840 of 5939 enquiries the Poisoning Severity Score (PSS) was known. The majority of patients (n = 4117; 70.5%) were asymptomatic (PSS 0), 28.0% (n = 1638) developed minor features (PSS 1), 1.3% (75 patients) developed moderate features (PSS 2) and 0.15% (nine patients) developed serious features (PSS 3). Four of these nine patients made a complete recovery, two died from exposure to drain cleaner and PVC solvent cleaner; the outcome in three was unknown. In the UK, advice from the NPIS is sought commonly regarding household products, but such exposures only rarely result in clinically serious features. As 65.5% of exposures were in children less than 5 years of age, parents clearly have an important role to play in ensuring that household products are stored safely at all times.

  2. Status of geological studies undertaken in France on the Oklo deposit since the Libreville Symposium

    International Nuclear Information System (INIS)

    Weber, F.

    1978-01-01

    The questions posed since the Libreville symposium can be grouped under four headings: origin of the deposits and the over-concentrations; degree of burial reached by the series; temperatures attained during the reactions, and effects of the reactions; perturbations subsequent to the reactions. These questions have been the subject of multidisciplinary investigations, including conventional petrographic and mineralogical investigations (Cogema, Fontenay-aux-Roses and the Centre for Sedimentology and Geochemistry of the Surface, Strasbourg), a study of fluid inclusions (Centre for Petrographic and Geochemical Research, Nancy), studies of organic material (French Institute of Petroleum, Rueil, and Cerchar, Verneuil-en-Halatte) and a study of fission traces (Rene Barnas Laboratory, Orsay). (author)

  3. Patterns of self-management practices undertaken by cancer survivors: variations in demographic factors.

    Science.gov (United States)

    Shneerson, C; Taskila, T; Holder, R; Greenfield, S; Tolosa, I; Damery, S; Gale, N

    2015-09-01

    The study purpose was to examine self-management (SM) use among cancer survivors; and to explore variations in uptake of SM in survivorship and whether these differed in relation to age, income, gender, ethnicity, cancer type and treatment type. This is an important area for exploration as SM utilisation has the potential to impact on the health status, health behaviours and quality of life (QoL) of cancer survivors. A postal survey was conducted among 445 cancer survivors identified from a hospital in the West Midlands, UK. Demographic data were collected and respondents were asked to identify which practices across six SM categories - diet, exercise, complementary and alternative medicine (CAM), psychological therapies, support groups and spirituality/religion - they had used (if any). The findings indicate that the large majority (91%) had used some form of SM after their cancer treatment. Exercise (84%) and diet (56%) were the most popular SM interventions for cancer survivors and socio-demographic and cancer-related factors were associated with SM uptake. These findings can form the basis for designing and implementing appropriate SM interventions aimed at improving the health, well-being and QoL of cancer survivors. © 2014 John Wiley & Sons Ltd.

  4. Renewal of the operating license. Activities, uncertainties and challenges to be undertaken by Asco NPP

    International Nuclear Information System (INIS)

    Diez, R. I.; Gonzalez Ayestaran, P.

    2015-01-01

    The management plan of life aims to analyze and manage properly, the effects of time and the operation in the structures, systems and / or components considered within its scope, so that the functions defined remain at their bases leave during their service life. (Author)

  5. Greenhouse effect and developing countries (state of the knowledge, research and actions to be undertaken)

    International Nuclear Information System (INIS)

    Riedacker, A.

    1991-01-01

    The forest contribution to the variations of atmospheric carbon dioxide and the threats that jeopardize them are first reviewed: deforestation in tropical zones, carbon de-storage, causes of the deforestation, potential of reforestation policies and agricultural intensive incitations, effects of climatic changes on forests. The contribution of energy consumption to atmospheric carbon dioxide increase is also evaluated and the energy conservation means to reduce CO 2 emissions are presented. Methane and other greenhouse gas emissions from forest and savannah fires, wood fuel utilization, etc. are examined and different recommendations specifically intended for developing countries are proposed

  6. Fixed or Rotating Night Shift Work Undertaken by Women: Implications for Fertility and Miscarriage.

    Science.gov (United States)

    Fernandez, Renae C; Marino, Jennifer L; Varcoe, Tamara J; Davis, Scott; Moran, Lisa J; Rumbold, Alice R; Brown, Hannah M; Whitrow, Melissa J; Davies, Michael J; Moore, Vivienne M

    2016-03-01

    This review summarizes the evidence concerning effects of night shift work on women's reproductive health, specifically difficulty in conceiving and miscarriage. We distinguish between fixed night shift and rotating night shift, as the population subgroups exposed, the social and biological mechanisms, and the magnitude of effects are likely to differ; of note, women working fixed night shift are known to have high tolerance for this schedule. We identified two relevant systematic reviews with meta-analyses and five additional studies. Night shift work may give rise to menstrual cycle disturbances, but effect sizes are imprecise. Endometriosis may be elevated in night shift workers, but evidence is only preliminary. Adequate data are lacking to assess associations between night shift work and infertility or time to pregnancy. The weight of evidence begins to point to working at night, whether in fixed or rotating shifts, as a risk factor for miscarriage. There are many methodological problems with this literature, with substantial variation in the definitions of night shift and schedule types making comparisons between studies difficult and pooling across studies questionable. Nevertheless, there appears to be grounds for caution and counselling where women have concerns about night shift work and their reproductive health. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  7. The highly successful safe remediation of the Fernald waste pits undertaken under the privatization model

    Energy Technology Data Exchange (ETDEWEB)

    Cherry, Mark; Lojek, Dave; Murphy, Con

    2003-02-23

    Remediation of eight waste pits at the Department of Energy (DOE) Fernald site, located northwest of Cincinnati, Ohio, involves excavating approximately one million tonnes in-situ of low-level waste which were placed in pits during Fernald's production era. This unique project, one of the largest in the history of CERCLA/Superfund, includes uranium and thorium contaminated waste, soils and sludges. These wet soils and sludges are thermally dried in a processing facility to meet Department of Transportation (DOT) transportation and disposal facility waste acceptance criteria, loaded into railcars and shipped to the Envirocare waste disposal facility at Clive, Utah. This project is now approximately 60% complete with more than 415,000 tonnes (460,000 tons) of waste material safely shipped in 74 unit trains to Envirocare. Work is scheduled to be completed in early 2005. Success to date demonstrates that a major DOE site remediation project can be safely and successfully executed in partnership with private industry, utilizing proven commercial best practices, existing site labor resources and support of local stakeholders. In 1997 under the DOE's privatization initiative, Fluor Fernald, Inc. (Fluor Fernald) solicited the services of the remediation industry to design, engineer, procure, construct, own and operate a facility that would undertake the remediation of the waste pits. The resulting procurement was awarded to IT Corporation, currently Shaw Environmental and Infrastructure, Inc. (Shaw). The contractor was required to finance the procurement and construction of its facilities and infrastructure. The contract was performance-based and payment would be made on the successful loadout of the waste from the facility on a per-ton basis meeting the Envirocare waste acceptance criteria. This paper details the performance to date, the challenges encountered, and the seamless partnering between DOE, the Environmental Protection Agency (EPA), Fluor Fernald, Shaw, labor un ions, and the local community in creating and executing a successful project.

  8. The results of the epidemiological survey undertaken after Chernobyl accident in adults population of Cracovian region

    International Nuclear Information System (INIS)

    Szybinski, Z.; Korzeniewska, D.; Przybyszowski, A.

    1991-01-01

    Epidemiologic studies following the Chernobyl accident were performed in region Cracow, including Cracow, Nowy Sacz and Kielce district. 1426 males and 2495 females were selected according to the random sample on the whole population of Cracow and Nowy Sacz, as well as in some selected areas in Swietokrzyskie Mountains, and in Kielce. The aim of the study was to asses the results of the prophylaxis with potassium iodine after the radiation and the incidence of the goiter in the population. It was stated, that 19.2% of the population in Cracow district, 16.9% in Nowy Sacz and 20% in Kielce received the prophylactic doses of K.I. 80% took mainly the Lugol solution, between May, the 1st and 5th, 1986. Among 18 of person showing side effects like gastrointestinal disturbances, 16 were of female sex. Goiter incidence according to WHO classification was 50.7%, 67.3% and 49.9% in Cracow, Nowy Sacz and Kielce, respectively. The difference between the incidence of goiter in males and females was 1:3. In women is rather 1st and 2nd degree of goiter, in men OB and 1st. Nodules of thyroid gland in the rural region Cracow, Nowy Sacz and Kielce were seen women in 10.8%, 1.7%, add 12.3% consecutively. Hormonal studies i.e. T 3 , T 4 , TSH serum concentration showed normal results in all groups studied. TSH concentration was the highest in the group OB. The microsomal and antithyreoglobulin antibodies level was the same independently on the prophylactic dose of Lugol solution. The high incidence of thyroid diseases not related to the accident was observed. The results show a moderate degree of goiter endemic in the region studied with very high incidence, especially in Nowy Sacz. 20% of adult population was given prophylactic dose of iodine, almost without side effects. (author). 8 refs, 1 fig, 7 tabs

  9. Tomographic multiphase flow measurement

    International Nuclear Information System (INIS)

    Sætre, C.; Johansen, G.A.; Tjugum, S.A.

    2012-01-01

    Measurement of multiphase flow of gas, oil and water is not at all trivial and in spite of considerable achievements over the past two decades, important challenges remain (). These are related to reducing measurement uncertainties arising from variations in the flow regime, improving long term stability and developing new means for calibration, adjustment and verification of the multiphase flow meters. This work focuses on the first two issues using multi gamma beam (MGB) measurements for identification of the type of flow regime. Further gamma ray tomographic measurements are used for reference of the gas/liquid distribution. For the MGB method one Am-241 source with principal emission at 59.5 keV is used because this relatively low energy enables efficient collimation and thereby shaping of the beams, as well as compact detectors. One detector is placed diametrically opposite the source whereas the second is positioned to the side so that this beam is close to the pipe wall. The principle is then straight forward to compare the measured intensities of these detectors and through that identify the flow pattern, i.e. the instantaneous cross-sectional gas-liquid distribution. The measurement setup also includes Compton scattering measurements, which can provide information about the changes in the water salinity for flow segments with high water liquid ratio and low gas fractions. By measuring the transmitted intensity in short time slots (<100ms), rapid regime variations are revealed. From this we can select the time sections suitable for salinity measurements. Since the salinity variations change at the time scale of hours, a running average can be performed to increase the accuracy of the measurements. Recent results of this work will be presented here. - Highlights: ► Multiphase flow gas-fraction and flow regime measurements by multi gamma ray beams. ► High-speed gamma ray tomograph as reference for the flow pattern and gas fraction. ► Dual modality

  10. Measuring memory.

    Science.gov (United States)

    Baddeley, A

    1988-01-01

    Three broad approaches to the measurement of memory functioning will be described. The first of these involves using memory as a general indicator of any dysfunction in the central nervous system. This approach will be illustrated using Sternberg's short-term memory scanning paradigm. Its strengths are that such tests are often very sensitive, but they are often very difficult to interpret both theoretically and in practical terms. A second approach is to use a range of tasks selected so as to tap different aspects of human memory. Such an approach is of considerably more theoretical interest, and is discussed in more detail by Eysenck (this volume). Its weaknesses are that theories of memory are still changing relatively quickly, and that mapping such results onto memory outside the laboratory is often complex. A third approach is to attempt a more direct measure of everyday memory. The use of questionnaires for this purpose will be critically discussed, and a new test of everyday memory will be described. This test, the Rivermead Behavioural Memory Test, correlates well with observations of memory lapses in patients, and appears to offer a promising new line of development.

  11. Molecular characterisation of parvoviruses from domestic cats reveals emergence of newer variants in India.

    Science.gov (United States)

    Mukhopadhyay, Hirak K; Nookala, Mangadevi; Thangamani, Nobal Rk; Sivaprakasam, Amsaveni; Antony, Prabhakar X; Thanislass, Jacob; Srinivas, Mouttou V; Pillai, Raghavan M

    2017-08-01

    Objectives The present study was undertaken to characterise the viral polypeptide 2 (VP2) gene of parvovirus from domestic cats in India. Methods The faecal samples from diarrhoeic/healthy domestic cats were collected from different geographical regions of India for screening by PCR assay followed by sequence analysis of the VP2 gene. Results Canine parvovirus (CPV)/feline panleukopenia virus (FPV) infections were found in 12 (11.3%) of 106 faecal samples tested. Two new CPV-2a (297Ala and Asn426) and three FPV strains were identified by VP2 gene analysis. Several unique and existing amino acid mutations were found, suggesting continuous evolution and emergence of newer variants. The phylogenetic analysis of the CPV sequences revealed that the two new CPV-2a strains from Mumbai (MC8) and Puducherry (P15) were clustered together in a single clade but had evolved independently and were ancestrally related to Chinese CPV-2a isolates. The FPV sequences (T-C-6 and T-C-1) from Thrissur, Kerala, formed a different clade (FPV clade) and were closely related to each other and had an ancestral relationship with an FPV isolate from the USA. Another FPV isolate from Goa (GC1) was positioned in the same clade but had evolved independently. Conclusions and relevance Detection of CPV in both diarrhoeic/healthy cats and the occurrence of FPV infection in a vaccinated cat provide new insights into parvovirus infections in cats in India.

  12. Indigenous Mortality (Revealed): The Invisible Illuminated

    Science.gov (United States)

    Ring, Ian; Arambula Solomon, Teshia G.; Gachupin, Francine C.; Smylie, Janet; Cutler, Tessa Louise; Waldon, John A.

    2015-01-01

    Inaccuracies in the identification of Indigenous status and the collection of and access to vital statistics data impede the strategic implementation of evidence-based public health initiatives to reduce avoidable deaths. The impact of colonization and subsequent government initiatives has been commonly observed among the Indigenous peoples of Australia, Canada, New Zealand, and the United States. The quality of Indigenous data that informs mortality statistics are similarly connected to these distal processes, which began with colonization. We discuss the methodological and technical challenges in measuring mortality for Indigenous populations within a historical and political context, and identify strategies for the accurate ascertainment and inclusion of Indigenous people in mortality statistics. PMID:25211754

  13. Venus's southern polar vortex reveals precessing circulation.

    Science.gov (United States)

    Luz, D; Berry, D L; Piccioni, G; Drossart, P; Politi, R; Wilson, C F; Erard, S; Nuccilli, F

    2011-04-29

    Initial images of Venus's south pole by the Venus Express mission have shown the presence of a bright, highly variable vortex, similar to that at the planet's north pole. Using high-resolution infrared measurements of polar winds from the Venus Express Visible and Infrared Thermal Imaging Spectrometer (VIRTIS) instrument, we show the vortex to have a constantly varying internal structure, with a center of rotation displaced from the geographic south pole by ~3 degrees of latitude and that drifts around the pole with a period of 5 to 10 Earth days. This is indicative of a nonsymmetric and varying precession of the polar atmospheric circulation with respect to the planetary axis.

  14. Radio Telescopes Reveal Unseen Galactic Cannibalism

    Science.gov (United States)

    2008-06-01

    Radio-telescope images have revealed previously-unseen galactic cannibalism -- a triggering event that leads to feeding frenzies by gigantic black holes at the cores of galaxies. Astronomers have long suspected that the extra-bright cores of spiral galaxies called Seyfert galaxies are powered by supermassive black holes consuming material. However, they could not see how the material is started on its journey toward the black hole. Optical/Radio Comparison Visible-light (left) and radio (right) image of galaxy pair: Radio image shows gas streaming between galaxies. CREDIT: Kuo et al., NRAO/AUI/NSF Click on image for more graphics. One leading theory said that Seyfert galaxies have been disturbed by close encounters with neighboring galaxies, thus stirring up their gas and bringing more of it within the gravitational reach of the black hole. However, when astronomers looked at Seyferts with visible-light telescopes, only a small fraction showed any evidence of such an encounter. Now, new images of hydrogen gas in Seyferts made using the National Science Foundation's Very Large Array (VLA) radio telescope show the majority of them are, in fact, disturbed by ongoing encounters with neighbor galaxies. "The VLA lifted the veil on what's really happening with these galaxies," said Cheng-Yu Kuo, a graduate student at the University of Virginia. "Looking at the gas in these galaxies clearly showed that they are snacking on their neighbors. This is a dramatic contrast with their appearance in visible starlight," he added. The effect of the galactic encounters is to send gas and dust toward the black hole and produce energy as the material ultimately is consumed. Black holes, concentrations of matter so dense that not even light can escape their gravitational pull, reside at the cores of many galaxies. Depending on how rapidly the black hole is eating, the galaxy can show a wide range of energetic activity. Seyfert galaxies have the mildest version of this activity, while

  15. Revealing Adaptive Management of Environmental Flows

    Science.gov (United States)

    Allan, Catherine; Watts, Robyn J.

    2018-03-01

    Managers of land, water, and biodiversity are working with increasingly complex social ecological systems with high uncertainty. Adaptive management (learning from doing) is an ideal approach for working with this complexity. The competing social and environmental demands for water have prompted interest in freshwater adaptive management, but its success and uptake appear to be slow. Some of the perceived "failure" of adaptive management may reflect the way success is conceived and measured; learning, rarely used as an indicator of success, is narrowly defined when it is. In this paper, we document the process of adaptive flow management in the Edward-Wakool system in the southern Murray-Darling Basin, Australia. Data are from interviews with environmental water managers, document review, and the authors' structured reflection on their experiences of adaptive management and environmental flows. Substantial learning occurred in relation to the management of environmental flows in the Edward-Wakool system, with evidence found in planning documents, water-use reports, technical reports, stakeholder committee minutes, and refereed papers, while other evidence was anecdotal. Based on this case, we suggest it may be difficult for external observers to perceive the success of large adaptive management projects because evidence of learning is dispersed across multiple documents, and learning is not necessarily considered a measure of success. We suggest that documentation and sharing of new insights, and of the processes of learning, should be resourced to facilitate social learning within the water management sector, and to help demonstrate the successes of adaptive management.

  16. Gas chromatographic measurement in water-steam circuits

    International Nuclear Information System (INIS)

    Zschetke, J.; Nieder, R.

    1984-01-01

    A gas chromatographic technique for measurements in water-steam circuits, which has been well known for many years, has been improved by design modifications. A new type of equipment developed for special measuring tasks on nuclear engineering plant also has a general application. To date measurements have been carried out on the ''Otto Hahn'' nuclear powered ship, on the KNK and AVR experimental nuclear power plants at Karlsruhe and Juelich respectively and on experimental boiler circuits. The measurements at the power plants were carried out under different operating conditions. In addition measurements during the alkali operating mode and during combined cycle operation were carried out on the AVR reactor. It has been possible to draw new conclusion from the many measurements undertaken. (orig.) [de

  17. A method for evaluating the effectiveness of site characterization measurements

    International Nuclear Information System (INIS)

    Ditmars, J.D.

    1987-01-01

    A quantitative approach for evaluating the effectiveness of site characterization measurement activities is developed and illustrated with an example application to hypothetical measurement schemes at a potential geologic repository site for radioactive waste. The method is a general one and could also be applied at sites for underground disposal of hazardous chemicals. The approach presumes that measurements will be undertaken to support predictions of the performance of some aspect of a constructed facility or natural system. It requires a quantitative performance objective, such as groundwater travel time or contaminant concentration, against which to compare predictions of performance. The approach recognizes that such predictions are uncertain because the measurements upon which they are based are uncertain. The effectiveness of measurement activities is quantified by a confidence index, β, that reflects the number of standard deviations separating the best estimate of performance from the predetermined performance objective. Measurements that reduce the uncertainty in predictions lead to increased values of β. 5 refs., 4 figs

  18. Measuring Quality

    DEFF Research Database (Denmark)

    Næsby, Torben

    The Danish Day Care Facilities Act (2015), which provides the curriculum on which day care education is based, does not stipulate very clearly what children should learn and therefore how educational processes in preschools should be organised. This means that we must accept that there are large...... local differences in the quality of day care facilities in Denmark (Nordahl et al, 2012; Hansen et al, 2016) and also that we in fact have little knowledge of whether the desired politically determined targets are being met or not and what the quality is really like. In order to measure the quality...... of preschool in Denmark a new research project using the ECERS 3 instrument has been launched. This could capture quality from a global quality standard’s perspective, building the basis for a further investigation of practice in Danish early childhood provisions and centers in a more narrow approach...

  19. MEASURING APPARATUS

    Science.gov (United States)

    Kohman, T.P.; Weissbourd, B.W.

    1959-02-17

    An ion chamber assembly is presented for measuring neutron emission of a relatively slow rate from a radioactive sample. The detecting apparatus comprises a container filled with neutron slowing material and having a cavity where a neutron source may be located centrally in the container. A plurality of ion chamber units are disposed equidistantly from the source and from each other for detecting the neutron radiation. Each of the ion chamber units has an ion chamber and a second chamber of substantially the same diameter as the ion chamber and in end-to-end relationship therewith. The second chamber contains paraffin and an axially disposed lead-in conductor for the ion chamber central electrode. The preamplifier circuit whose input is connected to the lead-in conductor is housed in a third container arranged in end-to-end relationship with the second chamber.

  20. Holography as a measuring tool

    International Nuclear Information System (INIS)

    Tozer, B.A.; Webster, J.M.

    1981-01-01

    Holography has advantages over conventional photography for the recording and direct measurement of physical structures. The three-dimensional reconstruction carries information equivalent to almost a million photographs. Other advantages include the depth of field, resolution, wide angle of view and information storage density. A number of possible applications of holography have been identified within the CEGB and a proposal to apply it during the post-irradiation examination of nuclear fuel elements is now well advanced. Optical inspection of discharged fuel elements from Advanced-Gas-Cooled Reactors, whether undertaken in the irradiated-fuel disposal system at the station or at a post-irradiation-examination centre, can normally be performed remotely. Because of the very high radiation levels near the surfaces of the fuel element, viewing must be carried out through windows about 1.5 metres thick. Conventional photography is possible in the fuel-disposal system, but a specialised camera is required and only relatively low-resolution photographs of the top of the element can be obtained. At the post-irradiation centre, elements are dismantled and a detailed study can then be made, but it is very laborious and consumes expensive radiation- 'cave' time. Holography offers the possibility of recording a three-dimensional image of a complete element, which can then be studied at leisure to provide information on the condition of individual fuel pins. The present state of development of this work at Marchwood Engineering Laboratories is described. (author)

  1. Cellular Dynamics Revealed by Digital Holographic Microscopy☆

    KAUST Repository

    Marquet, P.

    2016-11-22

    Digital holographic microscopy (DHM) is a new optical method that provides, without the use of any contrast agent, real-time, three-dimensional images of transparent living cells, with an axial sensitivity of a few tens of nanometers. They result from the hologram numerical reconstruction process, which permits a sub wavelength calculation of the phase shift, produced on the transmitted wave front, by the optically probed cells, namely the quantitative phase signal (QPS). Specifically, in addition to measurements of cellular surface morphometry and intracellular refractive index (RI), various biophysical cellular parameters including dry mass, absolute volume, membrane fluctuations at the nanoscale and biomechanical properties, transmembrane water permeability as swell as current, can be derived from the QPS. This article presents how quantitative phase DHM (QP-DHM) can explored cell dynamics at the nanoscale with a special attention to both the study of neuronal dynamics and the optical resolution of local neuronal network.

  2. Microradiometers Reveal Ocean Health, Climate Change

    Science.gov (United States)

    2013-01-01

    When NASA researcher Stanford Hooker is in the field, he pays close attention to color. For Hooker, being in the field means being at sea. On one such research trip to the frigid waters of the Arctic, with a Coast Guard icebreaker looming nearby and the snow-crusted ice shelf a few feet away, Hooker leaned over the edge of his small boat and lowered a tethered device into the bright turquoise water, a new product devised by a NASA partner and enabled by a promising technology for oceanographers and atmospheric scientists alike. Color is a function of light. Pure water is clear, but the variation in color observed during a visit to the beach or a flight along a coastline depends on the water s depth and the constituents in it, how far down the light penetrates and how it is absorbed and scattered by dissolved and suspended material. Hooker cares about ocean color because of what it can reveal about the health of the ocean, and in turn, the health of our planet. "The main thing we are interested in is the productivity of the water," Hooker says. The seawater contains phytoplankton, microscopic plants, which are the food base for the ocean s ecosystems. Changes in the water s properties, whether due to natural seasonal effects or human influence, can lead to problems for delicate ecosystems such as coral reefs. Ocean color can inform researchers about the quantities and distribution of phytoplankton and other materials, providing clues as to how the world ocean is changing. NASA s Coastal Zone Color Scanner, launched in 1978, was the first ocean color instrument flown on a spacecraft. Since then, the Agency s ocean color research capabilities have become increasingly sophisticated with the launch of the SeaWiFS instrument in 1997 and the twin MODIS instruments carried into orbit on NASA s Terra (1999) and Aqua (2002) satellites. The technology provides sweeping, global information on ocean color on a scale unattainable by any other means. One issue that arises from

  3. Distributed neural system for emotional intelligence revealed by lesion mapping

    Science.gov (United States)

    Colom, Roberto; Grafman, Jordan

    2014-01-01

    Cognitive neuroscience has made considerable progress in understanding the neural architecture of human intelligence, identifying a broadly distributed network of frontal and parietal regions that support goal-directed, intelligent behavior. However, the contributions of this network to social and emotional aspects of intellectual function remain to be well characterized. Here we investigated the neural basis of emotional intelligence in 152 patients with focal brain injuries using voxel-based lesion-symptom mapping. Latent variable modeling was applied to obtain measures of emotional intelligence, general intelligence and personality from the Mayer, Salovey, Caruso Emotional Intelligence Test (MSCEIT), the Wechsler Adult Intelligence Scale and the Neuroticism-Extroversion-Openness Inventory, respectively. Regression analyses revealed that latent scores for measures of general intelligence and personality reliably predicted latent scores for emotional intelligence. Lesion mapping results further indicated that these convergent processes depend on a shared network of frontal, temporal and parietal brain regions. The results support an integrative framework for understanding the architecture of executive, social and emotional processes and make specific recommendations for the interpretation and application of the MSCEIT to the study of emotional intelligence in health and disease. PMID:23171618

  4. Distributed neural system for emotional intelligence revealed by lesion mapping.

    Science.gov (United States)

    Barbey, Aron K; Colom, Roberto; Grafman, Jordan

    2014-03-01

    Cognitive neuroscience has made considerable progress in understanding the neural architecture of human intelligence, identifying a broadly distributed network of frontal and parietal regions that support goal-directed, intelligent behavior. However, the contributions of this network to social and emotional aspects of intellectual function remain to be well characterized. Here we investigated the neural basis of emotional intelligence in 152 patients with focal brain injuries using voxel-based lesion-symptom mapping. Latent variable modeling was applied to obtain measures of emotional intelligence, general intelligence and personality from the Mayer, Salovey, Caruso Emotional Intelligence Test (MSCEIT), the Wechsler Adult Intelligence Scale and the Neuroticism-Extroversion-Openness Inventory, respectively. Regression analyses revealed that latent scores for measures of general intelligence and personality reliably predicted latent scores for emotional intelligence. Lesion mapping results further indicated that these convergent processes depend on a shared network of frontal, temporal and parietal brain regions. The results support an integrative framework for understanding the architecture of executive, social and emotional processes and make specific recommendations for the interpretation and application of the MSCEIT to the study of emotional intelligence in health and disease.

  5. A measurement device for electromagnetic flow tomography

    Science.gov (United States)

    Vauhkonen, M.; Hänninen, A.; Lehtikangas, O.

    2018-01-01

    Electromagnetic flow meters have succesfully been used in many industries to measure the mean flow velocity of conductive liquids. This technology works reliably in single phase flows with axisymmetric flow profiles but can be inaccurate with asymmetric flows, which are encountered, for example, in multiphase flows, pipe elbows and T-junctions. Some computational techniques and measurement devices with multiple excitation coils and measurement electrodes have recently been proposed to be used in cases of asymmetric flows. In earlier studies, we proposed a computational approach for electromagnetic flow tomography (EMFT) for estimating velocity fields utilizing several excitation coils and a set of measurement electrodes attached to the surface of the pipe. This approach has been shown to work well with simulated data but has not been tested extensively with real measurements. In this paper, an EMFT system with four excitation coils and 16 measurement electrodes is introduced. The system is capable of using both square wave and sinusoidal coil current excitations and all the coils can be excited individually, also enabling parallel excitations with multiple frequencies. The studies undertaken in the paper demonstrate that the proposed EMFT system, together with the earlier introduced velocity field reconstruction approach, is capable of producing reliable velocify field estimates in a laboratory environment with both axisymmetric and asymmetric single phase flows.

  6. Transcriptomic variation in a coral reveals pathways of clonal organisation

    DEFF Research Database (Denmark)

    K Bay, Line; Nielsen, Henrik Bjørn; Jarmer, Hanne Østergaard

    2009-01-01

    A microarray study was undertaken to examine the potential for clonal gene expression variation in a branching reef building coral, Acropora millepora. The role of small-scale gradients in light and water flow was examined by comparing gene expression levels between branch elevation (tip and base...... of mechanical stress and require greater levels of photo-protection associated with higher water flow and light levels. This study therefore confirms transcriptomic variation in response to small-scale environmental gradients consistent with differential resource allocation in clonal coral colonies. (C) 2009...

  7. MYSTERIES OF THE HUMAN FETUS REVEALED.

    Science.gov (United States)

    Sandman, Curt A

    2015-09-01

    The impressive program of research from the DiPietro laboratory succeeds in its aim to document the ontogeny of human fetal neurobehavioral development. From studies of great depth and breadth, and wielding creative methods of assessment, DiPietro et al. open a window into the largely inaccessible developing human fetal brain. This commentary, with reference to the seminal cardiovascular studies of the Laceys, supports the measures of the fetal heart to index fetal well-being and to provide evidence of stimulus processing. A separate case is made that the DiPietro program provides unique and invaluable information for assessing the influential Developmental Origins of Health and Disease or Fetal Programming Models. The goal of these models, to predict or understand the influences of early experience or response patterns on later postnatal life, is identical to the ultimate goal of the DiPietro program. Because human fetal behavior is uncontaminated by socialization or parenting or peers, it may be the best reflection of fetal exposures. The remarkable neurobehavioral profiles generated by the DiPietro program can make a critical contribution to the Fetal Programming Model in terms of sensitive and critical periods of nervous system vulnerability and to specify gestational periods of neurobehavioral risk. © 2015 The Society for Research in Child Development, Inc.

  8. The challenge of change in acute mental health services: measuring staff perceptions of barriers to change and their relationship to job status and satisfaction using a new measure (VOCALISE).

    Science.gov (United States)

    Laker, Caroline; Callard, Felicity; Flach, Clare; Williams, Paul; Sayer, Jane; Wykes, Til

    2014-02-20

    Health services are subject to frequent changes, yet there has been insufficient research to address how staff working within these services perceive the climate for implementation. Staff perceptions, particularly of barriers to change, may affect successful implementation and the resultant quality of care. This study measures staff perceptions of barriers to change in acute mental healthcare. We identify whether occupational status and job satisfaction are related to these perceptions, as this might indicate a target for intervention that could aid successful implementation. As there were no available instruments capturing staff perceptions of barriers to change, we created a new measure (VOCALISE) to assess this construct. All nursing staff from acute in-patient settings in one large London mental health trust were eligible. Using a participatory method, a nurse researcher interviewed 32 staff to explore perceptions of barriers to change. This generated a measure through thematic analyses and staff feedback (N = 6). Psychometric testing was undertaken according to standard guidelines for measure development (N = 40, 42, 275). Random effects models were used to explore the associations between VOCALISE, occupational status, and job satisfaction (N = 125). VOCALISE was easy to understand and complete, and showed acceptable reliability and validity. The factor analysis revealed three underlying constructs: 'confidence,' 'de-motivation' and 'powerlessness.' Staff with negative perceptions of barriers to change held more junior positions, and had poorer job satisfaction. Qualitatively, nursing assistants expressed a greater sense of organisational unfairness in response to change. VOCALISE can be used to explore staff perceptions of implementation climate and to assess how staff attitudes shape the successful outcomes of planned changes. Negative perceptions were linked with poor job satisfaction and to those occupying more junior roles, indicating a

  9. Final Report for SERDP Project RC-1649: Advanced Chemical Measurements of Smoke from DoD-prescribed Burns

    Science.gov (United States)

    T.J. Johnson; R.J. Yokelson; S.K. Akagi; I.R. Burling; D.R. Weise; S.P. Urbanski; C.E. Stockwell; J. Reardon; E.N. Lincoln; L.T.M. Profeta; A. Mendoza; M.D.W. Schneider; R.L. Sams; S.D. Williams; C.E. Wold; D.W.T. Griffith; M. Cameron; J.B. Gilman; C. Warneke; J.M. Roberts; P. Veres; W.C. Kuster; J de Gouw

    2014-01-01

    Project RC-1649, "Advanced Chemical Measurement of Smoke from DoD-prescribed Burns" was undertaken to use advanced instrumental techniques to study in detail the particulate and vapor-phase chemical composition of the smoke that results from prescribed fires used as a land management tool on DoD bases, particularly bases in the southeastern U.S. The statement...

  10. Model measurements in the cryogenic National Transonic Facility - An overview

    Science.gov (United States)

    Holmes, H. K.

    1985-01-01

    In the operation of the National Transonic Facility (NTF) higher Reynolds numbers are obtained on the basis of a utilization of low operational temperatures and high pressures. Liquid nitrogen is used as cryogenic medium, and temperatures in the range from -320 F to 160 F can be employed. A maximum pressure of 130 psi is specified, while the NTF design parameter for the Reynolds number is 120,000,000. In view of the new requirements regarding the measurement systems, major developments had to be undertaken in virtually all wind tunnel measurement areas and, in addition, some new measurement systems were needed. Attention is given to force measurement, pressure measurement, model attitude, model deformation, and the data system.

  11. Running over rough terrain reveals limb control for intrinsic stability.

    Science.gov (United States)

    Daley, Monica A; Biewener, Andrew A

    2006-10-17

    Legged animals routinely negotiate rough, unpredictable terrain with agility and stability that outmatches any human-built machine. Yet, we know surprisingly little about how animals accomplish this. Current knowledge is largely limited to studies of steady movement. These studies have revealed fundamental mechanisms used by terrestrial animals for steady locomotion. However, it is unclear whether these models provide an appropriate framework for the neuromuscular and mechanical strategies used to achieve dynamic stability over rough terrain. Perturbation experiments shed light on this issue, revealing the interplay between mechanics and neuromuscular control. We measured limb mechanics of helmeted guinea fowl (Numida meleagris) running over an unexpected drop in terrain, comparing their response to predictions of the mass-spring running model. Adjustment of limb contact angle explains 80% of the variation in stance-phase limb loading following the perturbation. Surprisingly, although limb stiffness varies dramatically, it does not influence the response. This result agrees with a mass-spring model, although it differs from previous findings on humans running over surfaces of varying compliance. However, guinea fowl sometimes deviate from mass-spring dynamics through posture-dependent work performance of the limb, leading to substantial energy absorption following the perturbation. This posture-dependent actuation allows the animal to absorb energy and maintain desired velocity on a sudden substrate drop. Thus, posture-dependent work performance of the limb provides inherent velocity control over rough terrain. These findings highlight how simple mechanical models extend to unsteady conditions, providing fundamental insights into neuromuscular control of movement and the design of dynamically stable legged robots and prosthetic devices.

  12. Ethiopian population dermatoglyphic study reveals linguistic stratification of diversity.

    Directory of Open Access Journals (Sweden)

    Seile Yohannes

    Full Text Available The manifestation of ethnic, blood type, & gender-wise population variations regarding Dermatoglyphic manifestations are of interest to assess intra-group diversity and differentiation. The present study reports on the analysis of qualitaive and quantitative finger Dermatoglyphic traits of 382 individuals cross-sectionally sampled from an administrative region of Ethiopia, consisting of five ethnic cohorts from the Afro-Asiatic & Nilo-Saharan affiliations. These Dermatoglyphic parameters were then applied in the assessment of diversity & differentiation, including Heterozygosity, Fixation, Panmixia, Wahlund's variance, Nei's measure of genetic diversity, and thumb & finger pattern genotypes, which were inturn used in homology inferences as summarized by a Neighbour-Joining tree constructed from Nei's standard genetic distance. Results revealed significant correlation between Dermatoglyphics & population parameters that were further found to be in concordance with the historical accounts of the ethnic groups. Such inductions as the ancient north-eastern presence and subsequent admixure events of the Oromos (PII= 15.01, the high diversity of the Amharas (H= 0.1978, F= 0.6453, and P= 0.4144, and the Nilo-Saharan origin of the Berta group (PII= 10.66 are evidences to this. The study has further tested the possibility of applying Dermatoglyphics in population genetic & anthropologic research, highlighting on the prospect of developing a method to trace back population origins & ancient movement patterns. Additionally, linguistic clustering was deemed significant for the Ethiopian population, coinciding with recent genome wide studies that have ascertained that linguistic clustering as to being more crucial than the geographical patterning in the Ethiopian context. Finally, Dermatoglyphic markers have been proven to be endowed with a strong potential as non-invasive preliminary tools applicable prior to genetic studies to analyze ethnically sub

  13. Ethiopian population dermatoglyphic study reveals linguistic stratification of diversity.

    Science.gov (United States)

    Yohannes, Seile; Bekele, Endashaw

    2015-01-01

    The manifestation of ethnic, blood type, & gender-wise population variations regarding Dermatoglyphic manifestations are of interest to assess intra-group diversity and differentiation. The present study reports on the analysis of qualitaive and quantitative finger Dermatoglyphic traits of 382 individuals cross-sectionally sampled from an administrative region of Ethiopia, consisting of five ethnic cohorts from the Afro-Asiatic & Nilo-Saharan affiliations. These Dermatoglyphic parameters were then applied in the assessment of diversity & differentiation, including Heterozygosity, Fixation, Panmixia, Wahlund's variance, Nei's measure of genetic diversity, and thumb & finger pattern genotypes, which were inturn used in homology inferences as summarized by a Neighbour-Joining tree constructed from Nei's standard genetic distance. Results revealed significant correlation between Dermatoglyphics & population parameters that were further found to be in concordance with the historical accounts of the ethnic groups. Such inductions as the ancient north-eastern presence and subsequent admixure events of the Oromos (PII= 15.01), the high diversity of the Amharas (H= 0.1978, F= 0.6453, and P= 0.4144), and the Nilo-Saharan origin of the Berta group (PII= 10.66) are evidences to this. The study has further tested the possibility of applying Dermatoglyphics in population genetic & anthropologic research, highlighting on the prospect of developing a method to trace back population origins & ancient movement patterns. Additionally, linguistic clustering was deemed significant for the Ethiopian population, coinciding with recent genome wide studies that have ascertained that linguistic clustering as to being more crucial than the geographical patterning in the Ethiopian context. Finally, Dermatoglyphic markers have been proven to be endowed with a strong potential as non-invasive preliminary tools applicable prior to genetic studies to analyze ethnically sub-divided populations and

  14. A Network Based Methodology to Reveal Patterns in Knowledge Transfer

    Directory of Open Access Journals (Sweden)

    Orlando López-Cruz

    2015-12-01

    Full Text Available This paper motivates, presents and demonstrates in use a methodology based in complex network analysis to support research aimed at identification of sources in the process of knowledge transfer at the interorganizational level. The importance of this methodology is that it states a unified model to reveal knowledge sharing patterns and to compare results from multiple researches on data from different periods of time and different sectors of the economy. This methodology does not address the underlying statistical processes. To do this, national statistics departments (NSD provide documents and tools at their websites. But this proposal provides a guide to model information inferences gathered from data processing revealing links between sources and recipients of knowledge being transferred and that the recipient detects as main source to new knowledge creation. Some national statistics departments set as objective for these surveys the characterization of innovation dynamics in firms and to analyze the use of public support instruments. From this characterization scholars conduct different researches. Measures of dimensions of the network composed by manufacturing firms and other organizations conform the base to inquiry the structure that emerges from taking ideas from other organizations to incept innovations. These two sets of data are actors of a two- mode-network. The link between two actors (network nodes, one acting as the source of the idea. The second one acting as the destination comes from organizations or events organized by organizations that “provide” ideas to other group of firms. The resulting demonstrated design satisfies the objective of being a methodological model to identify sources in knowledge transfer of knowledge effectively used in innovation.

  15. Impaired Phosphate Tolerance Revealed With an Acute Oral Challenge.

    Science.gov (United States)

    Turner, Mandy E; White, Christine A; Hopman, Wilma M; Ward, Emilie C; Jeronimo, Paul S; Adams, Michael A; Holden, Rachel M

    2018-01-01

    Elevated serum phosphate is consistently linked with cardiovascular disease (CVD) events and mortality in the setting of normal and impaired kidney function. However, serum phosphate does not often exceed the upper limit of normal until glomerular filtration rate (GFR) falls below 30 mL/min/m 2 . It was hypothesized that the response to an oral, bioavailable phosphate load will unmask impaired phosphate tolerance, a maladaptation not revealed by baseline serum phosphate concentrations. In this study, rats with varying kidney function as well as normo-phosphatemic human subjects, with inulin-measured GFR (13.2 to 128.3mL/min), received an oral phosphate load. Hormonal and urinary responses were evaluated over 2 hours. Results revealed that the more rapid elevation of serum phosphate was associated with subjects and rats with higher levels of kidney function, greater responsiveness to acute changes in parathyroid hormone (PTH), and significantly more urinary phosphate at 2 hours. In humans, increases in urinary phosphate to creatinine ratio did not correlate with baseline serum phosphate concentrations but did correlate strongly to early increase of serum phosphate. The blunted rise in serum phosphate in rats with CKD was not the result of altered absorption. This result suggests acute tissue deposition may be altered in the setting of kidney function impairment. Early recognition of impaired phosphate tolerance could translate to important interventions, such as dietary phosphate restriction or phosphate binders, being initiated at much higher levels of kidney function than is current practice. © 2017 American Society for Bone and Mineral Research. © 2017 American Society for Bone and Mineral Research.

  16. Process control and dosimetry applied to establish a relation between reference dose measurements and actual dose distribution

    International Nuclear Information System (INIS)

    Ehlerman, D.A.E.

    2001-01-01

    The availability of the first commercial dose level indicator prompted attempts to verify radiation absorbed dose to items under quarantine control (e.g. for insect disinfestation) by some indicator attached to these items. Samples of the new commercial dose level indicators were tested for their metrological properties using gamma and electron irradiation. The devices are suitable for the intended purpose and the subjective judgement whether the threshold dose was surpassed is possible in a reliable manner. The subjective judgements are completely backed by the instrumental results. Consequently, a prototype reader was developed; first tests were successful. The value of dose level indicators and the implications of its use for food or quarantine inspection depends on a link between dose measured (indicated) at the position of such indicator and the characteristic parameters of the frequency distribution of dose throughout the product load i.e. a box or a container or a whole batch of multiple units. Therefore, studies into variability and statistical properties of dose distributions obtained under a range of commercial situations were undertaken. Gamma processing at a commercial multipurpose contract irradiator, electron processing and bremsstrahlung applications at a largescale research facility were included; products were apples, potatoes, wheat, maize, pistachio. Studies revealed that still more detailed information on irradiation geometries are needed in order to render meaningful information from dose label indicators. (author)

  17. Study of a twisted ATLAS SCT Barrel deformation as revealed by a photogrammetric survey

    CERN Document Server

    Dobson, E; Heinemann, F; Karagoz-Unel, M

    2007-01-01

    A photogrammetry survey on the SCT barrels was performed as an engineering check on the structure of the ATLAS Semiconductor Tracker (SCT) shortly after construction. Analysis of the data obtained revealed small scale elliptical deformation as well as a twist of the structure. The results of the survey are presented as well as interpolation of the measured targets to the module positions and a comparison with track based alignment measurements.

  18. Absolute and Relative Time-Consistent Revealed Preferences

    OpenAIRE

    T. DEMUYNCK

    2007-01-01

    We introduce an Absolute (Relative) Time-consistent Axiom of Revealed Preference which characterizes the consistency of a choice function with the property of absolute (relative) time-consistency and impatience. The axiom requires that the absolute (relative) time-consistent and impatient closure of the revealed preference relation does not conflict with the strict revealed preference relation.

  19. VLBA Reveals Closest Pair of Supermassive Black Holes

    Science.gov (United States)

    2006-05-01

    Astronomers using the National Science Foundation's Very Long Baseline Array (VLBA) radio telescope have found the closest pair of supermassive black holes ever discovered in the Universe -- a duo of monsters that together are more than 150 million times more massive than the Sun and closer together than the Earth and the bright star Vega. The VLBA The VLBA CREDIT: NRAO/AUI/NSF "These two giant black holes are only about 24 light-years apart, and that's more than 100 times closer than any pair found before," said Cristina Rodriguez, of the University of New Mexico (UNM) and Simon Bolivar University in Venezuela. Black holes are concentrations of mass with gravity so strong that not even light can escape them. The black hole pair is in the center of a galaxy called 0402+379, some 750 million light-years from Earth. Astronomers presume that each of the supermassive black holes was once at the core of a separate galaxy, then the two galaxies collided, leaving the black holes orbiting each other. The black holes orbit each other about once every 150,000 years, the scientists say. "If two black holes like these were to collide, that event would create the type of strong gravitational waves that physicists hope to detect with instruments now under construction," said Gregory Taylor, of UNM. The physicists will need to wait, though: the astronomers calculate that the black holes in 0402+379 won't collide for about a billion billion years. "There are some things that might speed that up a little bit," Taylor remarked. An earlier VLBA study of 0402+379, an elliptical galaxy, showed the pair of radio-wave-emitting objects near its core. Further studies using the VLBA and the Hobby-Eberly Telescope in Texas, revealed that the pair of objects is indeed a pair of supermassive black holes. "We needed the ultra-sharp radio 'vision' of the VLBA, particularly at the high radio frequencies of 22 and 43 GigaHertz, to get the detail needed to show that those objects are a pair of

  20. Thermal conductivity measurements of pacific illite sediment

    Science.gov (United States)

    Hickox, C. E.; McVey, D. F.; Miller, J. B.; Olson, L. O.; Silva, A. J.

    1986-07-01

    Results are reported for effective thermal conductivity measurements performed in situ and in core samples of illite marine sediment. The measurements were obtained during a recent oceanographic expedition to a study site in the north central region of the Pacific Ocean. This study was undertaken in support of the U.S. Subseabed Disposal Project, the purpose of which is to investigate the scientific feasibility of using the fine-grained sediments of the sea floor as a repository for high-level nuclear waste. In situ measurements were made and 1.5-m-long hydrostatic piston cores were taken, under remote control, from a platform that was lowered to the sea floor, 5844 m below sea level. The in situ measurement of thermal conductivity was made at a nominal depth of 80 cm below the sediment surface using a specially developed, line-source, needle probe. Thermal conductivity measurements in three piston cores and one box core (obtained several kilometers from the study site) were made on shipboard using a miniature needle probe. The in situ thermal conductivity was approximately 0.91 W · m-1 · K-1. Values determined from the cores were within the range 0.81 to 0.89 W · m-1 · K-1.

  1. Thermal conductivity measurements of Pacific illite sediment

    International Nuclear Information System (INIS)

    Hickox, C.E.; McVey, D.F.; Miller, J.B.; Olson, L.O.; Silva, A.J.

    1986-01-01

    Results are reported for effective thermal conductivity measurements performed in situ and in core samples of illite marine sediment. The measurements were obtained during a recent oceanographic expedition to a study site in the north central region of the Pacific Ocean. This study was undertaken in support of the US Subseabed Disposal Project, the purpose of which is to investigate the scientific feasibility of using the fine grained sediments of the sea floor as a repository for high level nuclear waste. In situ measurements were made and 1.5-meter long hydrostatic piston cores were taken, under remote control, from a platform that was lowered to the sea floor, 5844 m below sea level. The in situ measurement of thermal conductivity was made at a nominal depth of 80 cm below the sediment surface using a specially developed, line source, needle probe. Thermal conductivity measurements in three piston cores and one box core (obtained several kilometers from the study site) were made on shipboard using a miniature needle probe. The in situ thermal conductivity was approximately 0.91 W/m.K. Values determined from the cores were within the range 0.81 to 0.89 W/m.K

  2. An ultrasonic technique for measuring stress in fasteners

    Science.gov (United States)

    Stevens, K. J.; Day, P.; Byron, D.

    1999-12-01

    High temperature bolting alloys are extensively used in the thermal power generation industry as for example, reheat ESV and Governor valve studs. Remnant life assessment methodologies and plant maintenance procedures require the monitoring of the operational stress levels in these fasteners. Some conventional ultrasonic techniques require longitudinal wave measurements to be undertaken when the nut on the bolt is loosened and then re-tightened. Other techniques use a combination of shear waves and longitudinal waves. In this paper, the problems and pitfalls associated with various ultrasonic techniques for measuring stress in bolts, is discussed. An ultrasonic technique developed for measuring the stress in Durehete 1055 bolts is presented. Material from a textured rolled bar has been used as a test bed in the development work. The technique uses shear wave birefringence and compression waves at several frequencies to measure texture, fastener length and the average stress. The technique was developed by making ultrasonic measurements on bolts tensioned in universal testing machines and a hydraulic nut. The ultrasonic measurements of residual stress have been checked against strain gauge measurements. The Durehete bolts have a hollow cylinder geometry of restricted dimensions, which significantly alters compression and shear wave velocities from bulk values and introduces hoop stresses which can be measured by rotating the polarization of the shear wave probe. Modelling of the experimental results has been undertaken using theories for the elastic wave propagation through waveguides. The dispersion equations allow the velocity and length of the fastener to be measured ultrasonically in some situations where the length of the fastener can not be measured directly with a vernier caliper or micrometer and/or where it is undesirable to loosen nuts to take calibration readings of the shear and compression wave velocities.

  3. An ultrasonic technique for measuring stress in fasteners

    International Nuclear Information System (INIS)

    Stevens, K. J.; Day, P.; Byron, D.

    1999-01-01

    High temperature bolting alloys are extensively used in the thermal power generation industry as for example, reheat ESV and Governor valve studs. Remnant life assessment methodologies and plant maintenance procedures require the monitoring of the operational stress levels in these fasteners. Some conventional ultrasonic techniques require longitudinal wave measurements to be undertaken when the nut on the bolt is loosened and then re-tightened. Other techniques use a combination of shear waves and longitudinal waves. In this paper, the problems and pitfalls associated with various ultrasonic techniques for measuring stress in bolts, is discussed. An ultrasonic technique developed for measuring the stress in Durehete 1055 bolts is presented. Material from a textured rolled bar has been used as a test bed in the development work. The technique uses shear wave birefringence and compression waves at several frequencies to measure texture, fastener length and the average stress. The technique was developed by making ultrasonic measurements on bolts tensioned in universal testing machines and a hydraulic nut. The ultrasonic measurements of residual stress have been checked against strain gauge measurements. The Durehete bolts have a hollow cylinder geometry of restricted dimensions, which significantly alters compression and shear wave velocities from bulk values and introduces hoop stresses which can be measured by rotating the polarization of the shear wave probe. Modelling of the experimental results has been undertaken using theories for the elastic wave propagation through waveguides. The dispersion equations allow the velocity and length of the fastener to be measured ultrasonically in some situations where the length of the fastener can not be measured directly with a vernier caliper or micrometer and/or where it is undesirable to loosen nuts to take calibration readings of the shear and compression wave velocities

  4. Lack of tissue renewal in human adult Achilles tendon is revealed by nuclear bomb (14)C

    DEFF Research Database (Denmark)

    Heinemeier, Katja Maria; Schjerling, Peter; Heinemeier, Jan

    2013-01-01

    the 14C bomb-pulse method. This method takes advantage of the dramatic increase in atmospheric levels of 14C, produced by nuclear bomb tests in 1955-1963, which is reflected in all living organisms. Levels of 14C were measured in 28 forensic samples of Achilles tendon core and 4 skeletal muscle samples...... is revealed by nuclear bomb 14C....

  5. Host?pathogen evolutionary signatures reveal dynamics and future invasions of vampire bat rabies

    OpenAIRE

    Streicker, Daniel G.; Winternitz, Jamie C.; Satterfield, Dara A.; Condori-Condori, Rene Edgar; Broos, Alice; Tello, Carlos; Recuenco, Sergio; Velasco-Villa, Andr?s; Altizer, Sonia; Valderrama, William

    2016-01-01

    Anticipating how epidemics will spread across landscapes requires understanding host dispersal events that are notoriously difficult to measure. Here, we contrast host and virus genetic signatures to resolve the spatiotemporal dynamics underlying geographic expansions of vampire bat rabies virus (VBRV) in Peru. Phylogenetic analysis revealed recent viral spread between populations that, according to extreme geographic structure in maternally inherited host mitochondrial DNA, appeared complete...

  6. Electricity electron measurement

    International Nuclear Information System (INIS)

    Kim, Sang Jin; Sung, Rak Jin

    1985-11-01

    This book deals with measurement of electricity and electron. It is divided into fourteen chapters, which depicts basic of electricity measurement, unit and standard, important electron circuit for measurement, instrument of electricity, impedance measurement, power and power amount measurement, frequency and time measurement, waveform measurement, record instrument and direct viewing instrument, super high frequency measurement, digital measurement on analog-digital convert, magnetic measurement on classification by principle of measurement, measurement of electricity application with principle sensors and systematization of measurement.

  7. Rheology of transgenic switchgrass reveals practical aspects of biomass processing.

    Science.gov (United States)

    Wan, Guigui; Frazier, Taylor; Jorgensen, Julianne; Zhao, Bingyu; Frazier, Charles E

    2018-01-01

    Mechanical properties of transgenic switchgrass have practical implications for biorefinery technologies. Presented are fundamentals for simple (thermo)mechanical measurements of genetically transformed switchgrass. Experimental basics are provided for the novice, where the intention is to promote collaboration between plant biologists and materials scientists. Stem sections were subjected to two stress modes: (1) torsional oscillation in the linear response region, and (2) unidirectional torsion to failure. Specimens were analyzed while submerged/saturated in ethylene glycol, simulating natural hydration and allowing experimental temperatures above 100 °C for an improved view of the lignin glass transition. Down-regulation of the 4-Coumarate:coenzyme A ligase gene (reduced lignin content and altered monomer composition) generally resulted in less stiff and weaker stems. These observations were associated with a reduction in the temperature and activation energy of the lignin glass transition, but surprisingly with no difference in the breadth and intensity of the tan  δ signal. The results showed promise in further investigations of how rheological methods relate to stem lignin content, composition, and functional properties in the field and in bioprocessing. Measurements such as these are complicated by small specimen size; however, torsional rheometers (relatively common in polymer laboratories) are well suited for this task. As opposed to the expense and complication of relative humidity control, solvent-submersion rheological methods effectively reveal fundamental structure/property relationships in plant tissues. Demonstrated are low-strain linear methods, and also nonlinear yield and failure analysis; the latter is very uncommon for typical rheological equipment.

  8. In-flight radiation measurements aboard French airliners

    International Nuclear Information System (INIS)

    Montagne, C.; Donne, J.P.; Pelcot, D.; Nguyen, V.D.; Bouisset, P.; Kerlau, G.

    1993-01-01

    Routine radiation monitoring has been carried out for more than 15 years aboard Air France airliners. Annual dose received by aircrews can be estimated in the 2-3 mSv range for subsonic long-haul aircrews. Recent dosimetric measurements, using CIRCE devices based on low-pressure TEPC microdosimetry techniques and by using new types of bubble damage detectors, seem to confirm partly these results. More investigations by these new techniques could be undertaken at other phases of the 11 year solar cycle. (author)

  9. Symbolic joint entropy reveals the coupling of various brain regions

    Science.gov (United States)

    Ma, Xiaofei; Huang, Xiaolin; Du, Sidan; Liu, Hongxing; Ning, Xinbao

    2018-01-01

    The convergence and divergence of oscillatory behavior of different brain regions are very important for the procedure of information processing. Measurements of coupling or correlation are very useful to study the difference of brain activities. In this study, EEG signals were collected from ten subjects under two conditions, i.e. eyes closed state and idle with eyes open. We propose a nonlinear algorithm, symbolic joint entropy, to compare the coupling strength among the frontal, temporal, parietal and occipital lobes and between two different states. Instead of decomposing the EEG into different frequency bands (theta, alpha, beta, gamma etc.), the novel algorithm is to investigate the coupling from the entire spectrum of brain wave activities above 4Hz. The coupling coefficients in two states with different time delay steps are compared and the group statistics are presented as well. We find that the coupling coefficient of eyes open state with delay consistently lower than that of eyes close state across the group except for one subject, whereas the results without delay are not consistent. The differences between two brain states with non-zero delay can reveal the intrinsic inter-region coupling better. We also use the well-known Hénon map data to validate the algorithm proposed in this paper. The result shows that the method is robust and has a great potential for other physiologic time series.

  10. Kinematics of Mass Transport Deposits revealed by magnetic fabrics

    Science.gov (United States)

    Weinberger, R.; Levi, T.; Alsop, G. I.; Marco, S.

    2017-08-01

    The internal deformation and movement directions of Mass Transport Deposits (MTDs) are key factors in understanding the kinematics and dynamics of their emplacement. Although these are relatively easy to recover from well-bedded sediments, they are more difficult to deduce from massive beds without visible strain markers. In order to test the applicability of using anisotropy of magnetic susceptibility (AMS) to determine MTD movement, we compare AMS fabrics, with structural measurements of visible kinematic indicators. Our case study involves the structural analysis of slumped lake sediments extensively exposed in MTDs within the Dead Sea Basin. Structural analyses of MTDs outcropping for >100 km reveal radial transport directions toward the basin depocenter. We show that the AMS fabrics display the same transport directions as inferred from structural analyses. Based on this similarity, we outline a robust procedure to obtain the transport direction of slumped MTDs from AMS fabrics. Variations in the magnetic fabrics and anisotropies in fold-thrust systems within the slumps match the various structural domains. We therefore suggest that magnetic fabrics and anisotropy variations in drill cores may reflect internal deformation within the slumps rather than different slumps. Obtaining magnetic fabrics from MTDs provides a viable way to infer the transport directions and internal deformation of MTDs and reconstruct the basin depocenter in ancient settings. The present results also have implications beyond the kinematics of MTDs, as their geometry resembles fold-thrust systems in other geological settings, scales, and tectonic environments.

  11. Puffy Hand Syndrome Revealed by a Severe Staphylococcal Skin Infection

    Directory of Open Access Journals (Sweden)

    Reyhan Amode

    2013-01-01

    Full Text Available Puffy hand syndrome develops after long-term intravenous drug addiction. It is characterized by a nonpitting edema, affecting the dorsal side of fingers and hands with puffy aspect. Frequency and severity of the complications of this syndrome are rarely reported. Local infectious complications such as cellulitis can be severe and can enable the diagnosis. Herein, we report the case of a 41-year-old man who went to the emergency department for abdominal pain, fever, and bullous lesions of legs and arms with edema. Bacteriologic examination of a closed bullous lesion evidenced a methicillin sensitive Staphylococcus aureus. The abdomen computed tomography excluded deep infections and peritoneal effusion. The patient was successfully treated by intravenous oxacillin and clindamycin. He had a previous history of intravenous heroin addiction. We retained the diagnosis of puffy hand syndrome revealed by a severe staphylococcal infection with toxic involvement mimicking a four limbs cellulitis. Puffy hand syndrome, apart from the chronic lymphedema treatment, has no specific medication available. Prophylactic measures against skin infections are essential.

  12. Revealing the structure of the world airline network

    Science.gov (United States)

    Verma, T.; Araújo, N. A. M.; Herrmann, H. J.

    2014-07-01

    Resilience of most critical infrastructures against failure of elements that appear insignificant is usually taken for granted. The World Airline Network (WAN) is an infrastructure that reduces the geographical gap between societies, both small and large, and brings forth economic gains. With the extensive use of a publicly maintained data set that contains information about airports and alternative connections between these airports, we empirically reveal that the WAN is a redundant and resilient network for long distance air travel, but otherwise breaks down completely due to removal of short and apparently insignificant connections. These short range connections with moderate number of passengers and alternate flights are the connections that keep remote parts of the world accessible. It is surprising, insofar as there exists a highly resilient and strongly connected core consisting of a small fraction of airports (around 2.3%) together with an extremely fragile star-like periphery. Yet, in spite of their relevance, more than 90% of the world airports are still interconnected upon removal of this core. With standard and unconventional removal measures we compare both empirical and topological perceptions for the fragmentation of the world. We identify how the WAN is organized into different classes of clusters based on the physical proximity of airports and analyze the consequence of this fragmentation.

  13. Revealing hidden regularities with a general approach to fission

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, Karl-Heinz; Jurado, Beatriz [Chemin du Solarium, CENBG, CNRS/IN2P3, B. P. 120, Gradignan (France)

    2015-12-15

    Selected aspects of a general approach to nuclear fission are described with the focus on the possible benefit of meeting the increasing need of nuclear data for the existing and future emerging nuclear applications. The most prominent features of this approach are the evolution of quantum-mechanical wave functions in systems with complex shape, memory effects in the dynamics of stochastic processes, the influence of the Second Law of thermodynamics on the evolution of open systems in terms of statistical mechanics, and the topological properties of a continuous function in multi-dimensional space. It is demonstrated that this approach allows reproducing the measured fission barriers and the observed properties of the fission fragments and prompt neutrons. Our approach is based on sound physical concepts, as demonstrated by the fact that practically all the parameters have a physical meaning, and reveals a high degree of regularity in the fission observables. Therefore, we expect a good predictive power within the region extending from Po isotopes to Sg isotopes where the model parameters have been adjusted. Our approach can be extended to other regions provided that there is enough empirical information available that allows determining appropriate values of the model parameters. Possibilities for combining this general approach with microscopic models are suggested. These are supposed to enhance the predictive power of the general approach and to help improving or adjusting the microscopic models. This could be a way to overcome the present difficulties for producing evaluations with the required accuracy. (orig.)

  14. Correlation measurement of squeezed light

    DEFF Research Database (Denmark)

    Krivitsky, Leonid; Andersen, Ulrik Lund; Dong, R.

    2009-01-01

    We study the implementation of a correlation measurement technique for the characterization of squeezed light which is nearly free of electronic noise. With two different sources of squeezed light, we show that the sign of the covariance coefficient, revealed from the time-resolved correlation data......, is witnessing the presence of squeezing in the system. Furthermore, we estimate the degree of squeezing using the correlation method and compare it to the standard homodyne measurement scheme. We show that the role of electronic detector noise is minimized using the correlation approach as opposed to homodyning...

  15. Adapting a measure of acculturation for cross-cultural research.

    Science.gov (United States)

    dela Cruz, F A; Padilla, G V; Agustin, E O

    2000-07-01

    Although Filipino Americans are projected to become the largest Asian American ethnic group in this millennium, no acculturation measure existed for this group. This article describes a systematic and replicable process used in adapting and modifying A Short Acculturation Scale for Hispanics (ASASH) for use with Filipino Americans. It depicts the multiple and iterative steps of translation and backtranslation to produce A Short Acculturation Scale for Filipino Americans (ASASFA) in English and in Tagalog--the Philippine national language. Also, it describes the methods undertaken for the measures to achieve linguistic and cross-cultural validity through content, technical, experiential, semantic, and conceptual equivalence. With the dearth of linguistically and culturally valid measures for immigrant populations, the adaptation of valid measures developed for other cultures remains a viable option.

  16. Evaluation of TRMM multi-satellite precipitation analysis (TMPA) against terrestrial measurement over a humid sub-tropical basin, India

    Science.gov (United States)

    Kumar, Dheeraj; Gautam, Amar Kant; Palmate, Santosh S.; Pandey, Ashish; Suryavanshi, Shakti; Rathore, Neha; Sharma, Nayan

    2017-08-01

    To support the GPM mission which is homologous to its predecessor, the Tropical Rainfall Measuring Mission (TRMM), this study has been undertaken to evaluate the accuracy of Tropical Rainfall Measuring Mission multi-satellite precipitation analysis (TMPA) daily-accumulated precipitation products for 5 years (2008-2012) using the statistical methods and contingency table method. The analysis was performed on daily, monthly, seasonal and yearly basis. The TMPA precipitation estimates were also evaluated for each grid point i.e. 0.25° × 0.25° and for 18 rain gauge stations of the Betwa River basin, India. Results indicated that TMPA precipitation overestimates the daily and monthly precipitation in general, particularly for the middle sub-basin in the non-monsoon season. Furthermore, precision of TMPA precipitation estimates declines with the decrease of altitude at both grid and sub-basin scale. The study also revealed that TMPA precipitation estimates provide better accuracy in the upstream of the basin compared to downstream basin. Nevertheless, the detection capability of daily TMPA precipitation improves with increase in altitude for drizzle rain events. However, the detection capability decreases during non-monsoon and monsoon seasons when capturing moderate and heavy rain events, respectively. The veracity of TMPA precipitation estimates was improved during the rainy season than during the dry season at all scenarios investigated. The analyses suggest that there is a need for better precipitation estimation algorithm and extensive accuracy verification against terrestrial precipitation measurement to capture the different types of rain events more reliably over the sub-humid tropical regions of India.

  17. Movement undertaken by newly graduated nurses towards the strengthening of their professional autonomy and towards patient autonomy Percepción de los enfermeros recién graduados sobre su autonomía profesional y sobre el proceso de la toma de decisiones del paciente Percepção de enfermeiros recém graduados sobre sua autonomia profissional e sobre o processo de tomada de decisão do paciente

    Directory of Open Access Journals (Sweden)

    Heloisa Wey Berti

    2008-04-01

    Full Text Available This study involved newly graduated nurses performing in a public hospital and aimed at apprehending how they interpret the reality of their practice as well as their knowledge and experiences; at identifying and problematizing aspects related to the caregiving practice in terms of compliance with the autonomy bioethical framework and at pointing out ways to overcome the problems identified. The strategy adopted for data collection was the focal group and the theoretical framework was based on the Grounded Theory. Two phenomena emerged from the results: 1 Perceiving the fragility of nurse and patient autonomy and 2 Moving towards the strengthening of nurse and patient autonomy. This allowed for the identification of the core category: movement undertaken by newly graduated nurses towards the strengthening of their professional autonomy and towards patient autonomy. Understanding the experience enabled us to expand the knowledge concerning newly graduate nurses' coping, thus favoring our action as nursing professors.El estudio fue realizado entre los enfermeros recién graduados que actúan en un hospital público con los objetivos de describir la percepción que tienen sobre su autonomía profesional y sobre el proceso de toma de decisiones del paciente. La estrategia adoptada para obtener los datos fue la de grupo focal y el marco metodológico la Grounded Theory. De los resultados surgieron dos fenómenos: 1 Percibiendo la fragilidad de la autonomía del enfermero y la del paciente. 2 Moviéndose en dirección a fortalecer la autonomía del enfermero y del paciente. Fue identificada la categoría central: movimiento emprendido por enfermeros recién formados en dirección a fortalecer la autonomía profesional y la autonomía del paciente. La comprensión de la experiencia permitió ampliar el conocimiento sobre los enfrentamientos de los enfermeros recién formados, lo que favoreció nuestra actuación como profesores de enfermería.O estudo

  18. Managing the marine aquarium trade: revealing the data gaps using ornamental polychaetes.

    Directory of Open Access Journals (Sweden)

    Joanna M Murray

    Full Text Available The marine aquarium industry has great potential to generate jobs in low-income coastal communities creating incentives for the maintenance of a healthy coral reef, if effectively managed. In the absence of current monitoring or legislation to govern the trade, baseline information regarding the species, number and source location of animals traded is missing despite being critical for its successful management and sustainability. An industry assessment to establish the number and provenance of species of ornamental polychaetes (sabellids and serpulids traded was undertaken across UK wholesalers and retailers. Six geographical regions exporting fan worms were identified. Singapore contributed the highest percentage of imports, but of only one worm "type" whereas Bali, the second largest source, supplied five different worm "types". Over 50% of UK retailers were supplied by one wholesaler while the remainder were stocked by a mixture of one other wholesaler and/or direct imports from the source country. We estimate that up to 18,500 ornamental polychaetes (16,980 sabellids and 1,018 serpulids are sold annually in the UK revealing a drastic underestimation of currently accepted trade figures. Incorrect identification (based on exporting region or visual characteristics of traded animals exacerbates the inaccuracy in market quantification, although identification of preserved sabellids using published keys proved just as inconclusive with high within-species variability and the potential for new or cryptic species. A re-description of the polychaete groups traded using a combination of molecular and morphological techniques is necessary for effective identification and market quantification. This study provides the first assessment of ornamental polychaetes but more importantly highlights the issues surrounding the collection of baseline information necessary to manage the aquarium trade. We recommend that future management should be community

  19. The bladed Bangiales (Rhodophyta) of the South Eastern Pacific: Molecular species delimitation reveals extensive diversity.

    Science.gov (United States)

    Guillemin, Marie-Laure; Contreras-Porcia, Loretto; Ramírez, María Eliana; Macaya, Erasmo C; Contador, Cristian Bulboa; Woods, Helen; Wyatt, Christopher; Brodie, Juliet

    2016-01-01

    A molecular taxonomic study of the bladed Bangiales of the South Eastern Pacific (coast of Chile) was undertaken based on sequence data of the mitochondrial COI and chloroplast rbcL for 193 specimens collected from Arica (18°S) in the north to South Patagonia (53°S) in the south. The results revealed for the first time that four genera, Porphyra, Pyropia, Fuscifolium and Wildemania were present in the region. Species delimitation was determined based on a combination of a General Mixed Yule Coalescence model (GMYC) and Automatic Barcode Gap Discovery (ABGD) coupled with detection of monophyly in tree reconstruction. The overall incongruence between the species delimitation methods within each gene was 29%. The GMYC method led to over-splitting groups, whereas the ABGD method had a tendency to lump groups. Taking a conservative approach to the number of putative species, at least 18 were recognized and, with the exception of the recently described Pyropia orbicularis, all were new to the Chilean flora. Porphyra and Pyropia were the most diverse genera with eight 'species' each, whereas only a 'single' species each was found for Fuscifolium and Wildemania. There was also evidence of recently diverging groups: Wildemania sp. was distinct but very closely related to W. amplissima from the Northern Hemisphere and raises questions in relation to such disjunct distributions. Pyropia orbicularis was very closely related to two other species, making species delimitation very difficult but provides evidence of an incipient speciation. The difference between the 'species' discovered and those previously reported for the region is discussed in relation to the difficulty of distinguishing species based on morphological identification. Copyright © 2015 Elsevier Inc. All rights reserved.

  20. Characterization of the fecal microbiome from non-human wild primates reveals species specific microbial communities.

    Directory of Open Access Journals (Sweden)

    Suleyman Yildirim

    Full Text Available BACKGROUND: Host-associated microbes comprise an integral part of animal digestive systems and these interactions have a long evolutionary history. It has been hypothesized that the gastrointestinal microbiome of humans and other non-human primates may have played significant roles in host evolution by facilitating a range of dietary adaptations. We have undertaken a comparative sequencing survey of the gastrointestinal microbiomes of several non-human primate species, with the goal of better understanding how these microbiomes relate to the evolution of non-human primate diversity. Here we present a comparative analysis of gastrointestinal microbial communities from three different species of Old World wild monkeys. METHODOLOGY/PRINCIPAL FINDINGS: We analyzed fecal samples from three different wild non-human primate species (black-and-white colobus [Colubus guereza], red colobus [Piliocolobus tephrosceles], and red-tailed guenon [Cercopithecus ascanius]. Three samples from each species were subjected to small subunit rRNA tag pyrosequencing. Firmicutes comprised the vast majority of the phyla in each sample. Other phyla represented were Bacterioidetes, Proteobacteria, Spirochaetes, Actinobacteria, Verrucomicrobia, Lentisphaerae, Tenericutes, Planctomycetes, Fibrobacateres, and TM7. Bray-Curtis similarity analysis of these microbiomes indicated that microbial community composition within the same primate species are more similar to each other than to those of different primate species. Comparison of fecal microbiota from non-human primates with microbiota of human stool samples obtained in previous studies revealed that the gut microbiota of these primates are distinct and reflect host phylogeny. CONCLUSION/SIGNIFICANCE: Our analysis provides evidence that the fecal microbiomes of wild primates co-vary with their hosts, and that this is manifested in higher intraspecies similarity among wild primate species, perhaps reflecting species

  1. Diversity and Structure of Diazotrophic Communities in Mangrove Rhizosphere, Revealed by High-Throughput Sequencing

    Directory of Open Access Journals (Sweden)

    Yanying Zhang

    2017-10-01

    Full Text Available Diazotrophic communities make an essential contribution to the productivity through providing new nitrogen. However, knowledge of the roles that both mangrove tree species and geochemical parameters play in shaping mangove rhizosphere diazotrophic communities is still elusive. Here, a comprehensive examination of the diversity and structure of microbial communities in the rhizospheres of three mangrove species, Rhizophora apiculata, Avicennia marina, and Ceriops tagal, was undertaken using high-throughput sequencing of the 16S rRNA and nifH genes. Our results revealed a great diversity of both the total microbial composition and the diazotrophic composition specifically in the mangrove rhizosphere. Deltaproteobacteria and Gammaproteobacteria were both ubiquitous and dominant, comprising an average of 45.87 and 86.66% of total microbial and diazotrophic communities, respectively. Sulfate-reducing bacteria belonging to the Desulfobacteraceae and Desulfovibrionaceae were the dominant diazotrophs. Community statistical analyses suggested that both mangrove tree species and additional environmental variables played important roles in shaping total microbial and potential diazotroph communities in mangrove rhizospheres. In contrast to the total microbial community investigated by analysis of 16S rRNA gene sequences, most of the dominant diazotrophic groups identified by nifH gene sequences were significantly different among mangrove species. The dominant diazotrophs of the family Desulfobacteraceae were positively correlated with total phosphorus, but negatively correlated with the nitrogen to phosphorus ratio. The Pseudomonadaceae were positively correlated with the concentration of available potassium, suggesting that diazotrophs potentially play an important role in biogeochemical cycles, such as those of nitrogen, phosphorus, sulfur, and potassium, in the mangrove ecosystem.

  2. HORMONE MEASUREMENT GUIDELINES: Tracing lipid metabolism: the value of stable isotopes.

    Science.gov (United States)

    Umpleby, A Margot

    2015-09-01

    Labelling molecules with stable isotopes to create tracers has become a gold-standard method to study the metabolism of lipids and lipoproteins in humans. There are a range of techniques which use stable isotopes to measure fatty acid flux and oxidation, hepatic fatty synthesis, cholesterol absorption and synthesis and lipoprotein metabolism in humans. Stable isotope tracers are safe to use, enabling repeated studies to be undertaken and allowing studies to be undertaken in children and pregnant women. This review provides details of the most appropriate tracers to use, the techniques which have been developed and validated for measuring different aspects of lipid metabolism and some of the limitations of the methodology. © 2015 Society for Endocrinology.

  3. Development of T9 type thin gap chamber and measurement of the detection efficiency

    International Nuclear Information System (INIS)

    Yan Zhen; Feng Cunfeng; Zhu Chengguang; Sun Yansheng; Zhang Naijian; He Mao

    2006-01-01

    The development and production of 400 sets of T9 type TGC (Thin Gap Chamber) for ATLAS experiment are undertaken by Shandong University. The process of development of T9 type TGC is introduced first and then the method of measuring the detection efficiency of the TGC is described. The testing result of detection efficiency of 288 sets of T9 type TGC built by Shandong University shows that all the detectors excellently fulfill the quality requirements of ATLAS experiment. (authors)

  4. NMR measurements of proton exchange between solvent and peptides and proteins

    International Nuclear Information System (INIS)

    Wojcik, J.; Ruszczynska, K.; Zhukov, I.; Ejchart, A.

    1999-01-01

    Scope and limitations of the NMR based methods, equilibration and magnetization transfer, for measuring proton exchange rates of amide protons in peptides and proteins with water protons are discussed. Equilibration is applied to very slow processes detected by hydrogen-deuterium exchange after a solute is dissolved in D 2 O. Magnetization transfer allows to study moderately rapid processes in H 2 O. A number of precautions should be undertaken in order to avoid systemic errors inherent in the magnetization transfer method. (author)

  5. Reliability of knee joint position sense measurement: a comparison between goniometry and image capture methods

    OpenAIRE

    Irving, Fiona; Russell, Joseph; Smith, Toby

    2016-01-01

    Aims: Evaluate the intra-rater and inter-rater reliability of hand-held goniometry compared to image capture (IMC) in the assessment of joint position sense (JPS) in healthy participants. Methodology: Repeated-measures observational study design was undertaken with 36 asymptomatic university students of both genders aged between 18 to 45 years. JPS in the knee was assessed by two assessors over two sessions (one-week interval) using hand-held goniometry and IMC methods. Joint position sense w...

  6. Velocity measurements in the near field of a diesel fuel injector by ultrafast imagery

    Science.gov (United States)

    Sedarsky, David; Idlahcen, Saïd; Rozé, Claude; Blaisot, Jean-Bernard

    2013-02-01

    This paper examines the velocity profile of fuel issuing from a high-pressure single-orifice diesel injector. Velocities of liquid structures were determined from time-resolved ultrafast shadow images, formed by an amplified two-pulse laser source coupled to a double-frame camera. A statistical analysis of the data over many injection events was undertaken to map velocities related to spray formation near the nozzle outlet as a function of time after start of injection. These results reveal a strong asymmetry in the liquid profile of the test injector, with distinct fast and slow regions on opposite sides of the orifice. Differences of ˜100 m/s can be observed between the `fast' and `slow' sides of the jet, resulting in different atomization conditions across the spray. On average, droplets are dispersed at a greater distance from the nozzle on the `fast' side of the flow, and distinct macrostructure can be observed under the asymmetric velocity conditions. The changes in structural velocity and atomization behavior resemble flow structures which are often observed in the presence of string cavitation produced under controlled conditions in scaled, transparent test nozzles. These observations suggest that widely used common-rail supply configurations and modern injectors can potentially generate asymmetric interior flows which strongly influence diesel spray morphology. The velocimetry measurements presented in this work represent an effective and relatively straightforward approach to identify deviant flow behavior in real diesel sprays, providing new spatially resolved information on fluid structure and flow characteristics within the shear layers on the jet periphery.

  7. Net ecosystem carbon dioxide exchange in tropical rainforests - sensitivity to environmental drivers and flux measurement methodology

    Science.gov (United States)

    Fu, Z.; Stoy, P. C.

    2017-12-01

    Tropical rainforests play a central role in the Earth system services of carbon metabolism, climate regulation, biodiversity maintenance, and more. They are under threat by direct anthropogenic effects including deforestation and indirect anthropogenic effects including climate change. A synthesis of the factors that determine the net ecosystem exchange of carbon dioxide (NEE) across multiple time scales in different tropical rainforests has not been undertaken to date. Here, we study NEE and its components, gross primary productivity (GPP) and ecosystem respiration (RE), across thirteen tropical rainforest research sites with 63 total site-years of eddy covariance data. Results reveal that the five ecosystems that have greater carbon uptakes (with the magnitude of GPP greater than 3000 g C m-2 y-1) sequester less carbon - or even lose it - on an annual basis at the ecosystem scale. This counterintuitive result is because high GPP is compensated by similar magnitudes of RE. Sites that provided subcanopy CO2 storage observations had higher average magnitudes of GPP and RE and consequently lower NEE, highlighting the importance of measurement methodology for understanding carbon dynamics in tropical rainforests. Vapor pressure deficit (VPD) constrained GPP at all sites, but to differing degrees. Many environmental variables are significantly related to NEE at time scales greater than one year, and NEE at a rainforest in Malaysia is significantly related to soil moisture variability at seasonal time scales. Climate projections from 13 general circulation models (CMIP5) under representative concentration pathway (RCP) 8.5 suggest that many current tropical rainforest sites on the cooler end of the current temperature range are likely to reach a climate space similar to present-day warmer sites by the year 2050, and warmer sites will reach a climate space not currently experienced. Results demonstrate the need to quantify if mature tropical trees acclimate to heat and

  8. Revealing the Earth's mantle from the tallest mountains using the Jinping Neutrino Experiment.

    Science.gov (United States)

    Šrámek, Ondřej; Roskovec, Bedřich; Wipperfurth, Scott A; Xi, Yufei; McDonough, William F

    2016-09-09

    The Earth's engine is driven by unknown proportions of primordial energy and heat produced in radioactive decay. Unfortunately, competing models of Earth's composition reveal an order of magnitude uncertainty in the amount of radiogenic power driving mantle dynamics. Recent measurements of the Earth's flux of geoneutrinos, electron antineutrinos from terrestrial natural radioactivity, reveal the amount of uranium and thorium in the Earth and set limits on the residual proportion of primordial energy. Comparison of the flux measured at large underground neutrino experiments with geologically informed predictions of geoneutrino emission from the crust provide the critical test needed to define the mantle's radiogenic power. Measurement at an oceanic location, distant from nuclear reactors and continental crust, would best reveal the mantle flux, however, no such experiment is anticipated. We predict the geoneutrino flux at the site of the Jinping Neutrino Experiment (Sichuan, China). Within 8 years, the combination of existing data and measurements from soon to come experiments, including Jinping, will exclude end-member models at the 1σ level, define the mantle's radiogenic contribution to the surface heat loss, set limits on the composition of the silicate Earth, and provide significant parameter bounds for models defining the mode of mantle convection.

  9. Revealing the Earth’s mantle from the tallest mountains using the Jinping Neutrino Experiment

    Science.gov (United States)

    Šrámek, Ondřej; Roskovec, Bedřich; Wipperfurth, Scott A.; Xi, Yufei; McDonough, William F.

    2016-09-01

    The Earth’s engine is driven by unknown proportions of primordial energy and heat produced in radioactive decay. Unfortunately, competing models of Earth’s composition reveal an order of magnitude uncertainty in the amount of radiogenic power driving mantle dynamics. Recent measurements of the Earth’s flux of geoneutrinos, electron antineutrinos from terrestrial natural radioactivity, reveal the amount of uranium and thorium in the Earth and set limits on the residual proportion of primordial energy. Comparison of the flux measured at large underground neutrino experiments with geologically informed predictions of geoneutrino emission from the crust provide the critical test needed to define the mantle’s radiogenic power. Measurement at an oceanic location, distant from nuclear reactors and continental crust, would best reveal the mantle flux, however, no such experiment is anticipated. We predict the geoneutrino flux at the site of the Jinping Neutrino Experiment (Sichuan, China). Within 8 years, the combination of existing data and measurements from soon to come experiments, including Jinping, will exclude end-member models at the 1σ level, define the mantle’s radiogenic contribution to the surface heat loss, set limits on the composition of the silicate Earth, and provide significant parameter bounds for models defining the mode of mantle convection.

  10. High temperature measurement of water vapor absorption

    Science.gov (United States)

    Keefer, Dennis; Lewis, J. W. L.; Eskridge, Richard

    1985-01-01

    An investigation was undertaken to measure the absorption coefficient, at a wavelength of 10.6 microns, for mixtures of water vapor and a diluent gas at high temperature and pressure. The experimental concept was to create the desired conditions of temperature and pressure in a laser absorption wave, similar to that which would be created in a laser propulsion system. A simplified numerical model was developed to predict the characteristics of the absorption wave and to estimate the laser intensity threshold for initiation. A non-intrusive method for temperature measurement utilizing optical laser-beam deflection (OLD) and optical spark breakdown produced by an excimer laser, was thoroughly investigated and found suitable for the non-equilibrium conditions expected in the wave. Experiments were performed to verify the temperature measurement technique, to screen possible materials for surface initiation of the laser absorption wave and to attempt to initiate an absorption wave using the 1.5 kW carbon dioxide laser. The OLD technique was proven for air and for argon, but spark breakdown could not be produced in helium. It was not possible to initiate a laser absorption wave in mixtures of water and helium or water and argon using the 1.5 kW laser, a result which was consistent with the model prediction.

  11. 21 CFR 1.21 - Failure to reveal material facts.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Failure to reveal material facts. 1.21 Section 1... GENERAL ENFORCEMENT REGULATIONS General Labeling Requirements § 1.21 Failure to reveal material facts. (a... that are: (1) Material in light of other representations made or suggested by statement, word, design...

  12. DNA markers reveal genetic structure and localized diversity of ...

    African Journals Online (AJOL)

    High genetic diversity was observed among the landraces for both marker systems. STRUCTURE analysis revealed 4 clusters of genetically differentiated groups of landraces. Cluster analysis revealed a close relationship between landraces along geographic proximity with genetic distance between landraces increasing ...

  13. Facial cellulitis revealing choreo-acanthocytosis: A case report ...

    African Journals Online (AJOL)

    We report a 62 year-old-man with facial cellulitis revealing choreo-acanthocytosis (ChAc). He showed chorea that started 20 years ago. The orofacial dyskinisia with tongue and cheek biting resulted in facial cellulitis. The peripheral blood smear revealed acanthocytosis of 25%. The overall of chorea, orofacial dyskinetic ...

  14. Can technology improve intershift report? What the research reveals.

    Science.gov (United States)

    Strople, Bernadette; Ottani, Patricia

    2006-01-01

    Shift report is a multifaceted process that serves to provide nurses with vital patient information to facilitate clinical decisions and patient care planning. A shift report also provides nurses with a forum for functions, such as patient problem solving and collaboration. The authors conducted a literature review, which indicates that current methodologies used to collect and convey patient information are ineffective and may contribute to negative patient outcomes. Data incongruence, legal implications, time constraints augmented by the nursing shortage, and the financial impact of shift report are also addressed. The literature reveals significant rationale for pioneering new and innovative methods of shift-to-shift communication. In the report To Err is Human: Building a Safe Health System, the Institute of Medicine attributes the deaths of up to 98,000 hospitalized Americans to medical errors, including communication failures [Institute of Medicine. (1999). To err is human: Building a safe health system. Report by the Committee on Quality of Health Care in America. Washington, DC: National Academy Press]. As a result, government policy makers and health care agencies have focused their attention on determining the root cause of errors to identify preventative measures, including the use of information technology [Institute of Medicine. (2004). Keeping patients safe: Transforming the work environment of nurses. Report by the Committee on Quality of Health Care in America. Washington, DC: National Academy Press]. Under these premises, the authors examined the process of nursing shift report and how it impacts patient outcomes. The use of computer technology and wireless modes of communication is explored as a means of improving the shift report process and, subsequently, health care outcomes and patient safety.

  15. Environmental barcoding reveals massive dinoflagellate diversity in marine environments.

    Directory of Open Access Journals (Sweden)

    Rowena F Stern

    2010-11-01

    Full Text Available Dinoflagellates are an ecologically important group of protists with important functions as primary producers, coral symbionts and in toxic red tides. Although widely studied, the natural diversity of dinoflagellates is not well known. DNA barcoding has been utilized successfully for many protist groups. We used this approach to systematically sample known "species", as a reference to measure the natural diversity in three marine environments.In this study, we assembled a large cytochrome c oxidase 1 (COI barcode database from 8 public algal culture collections plus 3 private collections worldwide resulting in 336 individual barcodes linked to specific cultures. We demonstrate that COI can identify to the species level in 15 dinoflagellate genera, generally in agreement with existing species names. Exceptions were found in species belonging to genera that were generally already known to be taxonomically challenging, such as Alexandrium or Symbiodinium. Using this barcode database as a baseline for cultured dinoflagellate diversity, we investigated the natural diversity in three diverse marine environments (Northeast Pacific, Northwest Atlantic, and Caribbean, including an evaluation of single-cell barcoding to identify uncultivated groups. From all three environments, the great majority of barcodes were not represented by any known cultured dinoflagellate, and we also observed an explosion in the diversity of genera that previously contained a modest number of known species, belonging to Kareniaceae. In total, 91.5% of non-identical environmental barcodes represent distinct species, but only 51 out of 603 unique environmental barcodes could be linked to cultured species using a conservative cut-off based on distances between cultured species.COI barcoding was successful in identifying species from 70% of cultured genera. When applied to environmental samples, it revealed a massive amount of natural diversity in dinoflagellates. This highlights

  16. Isotope analysis reveals foraging area dichotomy for atlantic leatherback turtles.

    Directory of Open Access Journals (Sweden)

    Stéphane Caut

    Full Text Available BACKGROUND: The leatherback turtle (Dermochelys coriacea has undergone a dramatic decline over the last 25 years, and this is believed to be primarily the result of mortality associated with fisheries bycatch followed by egg and nesting female harvest. Atlantic leatherback turtles undertake long migrations across ocean basins from subtropical and tropical nesting beaches to productive frontal areas. Migration between two nesting seasons can last 2 or 3 years, a time period termed the remigration interval (RI. Recent satellite transmitter data revealed that Atlantic leatherbacks follow two major dispersion patterns after nesting season, through the North Gulf Stream area or more eastward across the North Equatorial Current. However, information on the whole RI is lacking, precluding the accurate identification of feeding areas where conservation measures may need to be applied. METHODOLOGY/PRINCIPAL FINDINGS: Using stable isotopes as dietary tracers we determined the characteristics of feeding grounds of leatherback females nesting in French Guiana. During migration, 3-year RI females differed from 2-year RI females in their isotope values, implying differences in their choice of feeding habitats (offshore vs. more coastal and foraging latitude (North Atlantic vs. West African coasts, respectively. Egg-yolk and blood isotope values are correlated in nesting females, indicating that egg analysis is a useful tool for assessing isotope values in these turtles, including adults when not available. CONCLUSIONS/SIGNIFICANCE: Our results complement previous data on turtle movements during the first year following the nesting season, integrating the diet consumed during the year before nesting. We suggest that the French Guiana leatherback population segregates into two distinct isotopic groupings, and highlight the urgent need to determine the feeding habitats of the turtle in the Atlantic in order to protect this species from incidental take by

  17. Polymer properties of polythymine as revealed by translational diffusion.

    Science.gov (United States)

    Doose, Sören; Barsch, Hannes; Sauer, Markus

    2007-08-15

    Biopolymers, such as single-stranded DNA (ssDNA), are often described as semiflexible polymers or wormlike chains. We investigated the length dependence of diffusional properties of homogeneous ssDNA (polythymine) with up to 100 nucleotides using fluorescence correlation spectroscopy. We found that the hydrodynamic radius Rh scales according to a power law, with an exponent between 0.5 and 0.7 depending on ionic strength I. With Rh being proportional to the square root of the persistence length Lp, we found that Lp approximately Im, with m=-0.22+/-0.01 for polythymine with 100 residues. For comparison, we performed molecular dynamics (MD) simulations with a force field that accounts for short-range interactions in vacuum, and determined the characteristic polymer properties end-to-end distance R, radius of gyration S, and persistence length Lp of various labeled and nonlabeled polythymine derivatives. We found excellent agreement for the length dependence of simulated S and experimental Rh measured at 100 mM NaCl, revealing that electrostatic interactions are completely shielded in aqueous solution at such ionic strength. MD simulations further showed that polythymine with >approximately 30 residues can be described as a semiflexible polymer with negligible influence of the fluorescent label; and that static flexibility is limited by geometrical and steric constraints as expressed by an intrinsic persistence length of approximately 1.7 nm. These results provide a benchmark for theories and MD simulations describing the influence of electrostatic interactions on polyelectrolyte properties, and thus help to develop a complete and accurate description of ssDNA.

  18. Revealing δ Cephei's Secret Companion and Intriguing Past

    Science.gov (United States)

    Anderson, R. I.; Sahlmann, J.; Holl, B.; Eyer, L.; Palaversa, L.; Mowlavi, N.; Süveges, M.; Roelens, M.

    2015-05-01

    Classical Cepheid variable stars are crucial calibrators of the cosmic distance scale thanks to a relation between their pulsation periods and luminosities. Their archetype, δ Cephei, is an important calibrator for this relation. In this paper, we show that δ Cephei is a spectroscopic binary based on newly obtained high-precision radial velocities. We combine these new data with literature data to determine the orbit, which has period 2201 days, semi-amplitude 1.5 km s-1, and high eccentricity (e = 0.647). We re-analyze Hipparcos intermediate astrometric data to measure δ Cephei's parallax (\\varpi =4.09+/- 0.16 mas) and find tentative evidence for an orbital signature, although we cannot claim detection. We estimate that Gaia will fully determine the astrometric orbit. Using the available information from spectroscopy, velocimetry, astrometry, and Geneva stellar evolution models ({{M}δ Cep}˜ 5.0-5.25 {{M}⊙ }), we constrain the companion mass to within 0.2 {{M}⊙ }\\lt {{M}2}\\lt 1.2. We discuss the potential of ongoing and previous interactions between the companion and δ Cephei near pericenter passage, informing reported observations of circumstellar material and bow shock. The orbit may have undergone significant changes due to a Kozai-Lidov mechanism driven by the outer (visual and astrometric) companion HD 213307. Our discovery of δ Cephei's nature as a spectroscopic binary exposes a hidden companion and reveals a rich and dynamical history of the archetype of classical Cepheid variables.

  19. Neural correlates of the LSD experience revealed by multimodal neuroimaging.

    Science.gov (United States)

    Carhart-Harris, Robin L; Muthukumaraswamy, Suresh; Roseman, Leor; Kaelen, Mendel; Droog, Wouter; Murphy, Kevin; Tagliazucchi, Enzo; Schenberg, Eduardo E; Nest, Timothy; Orban, Csaba; Leech, Robert; Williams, Luke T; Williams, Tim M; Bolstridge, Mark; Sessa, Ben; McGonigle, John; Sereno, Martin I; Nichols, David; Hellyer, Peter J; Hobden, Peter; Evans, John; Singh, Krish D; Wise, Richard G; Curran, H Valerie; Feilding, Amanda; Nutt, David J

    2016-04-26

    Lysergic acid diethylamide (LSD) is the prototypical psychedelic drug, but its effects on the human brain have never been studied before with modern neuroimaging. Here, three complementary neuroimaging techniques: arterial spin labeling (ASL), blood oxygen level-dependent (BOLD) measures, and magnetoencephalography (MEG), implemented during resting state conditions, revealed marked changes in brain activity after LSD that correlated strongly with its characteristic psychological effects. Increased visual cortex cerebral blood flow (CBF), decreased visual cortex alpha power, and a greatly expanded primary visual cortex (V1) functional connectivity profile correlated strongly with ratings of visual hallucinations, implying that intrinsic brain activity exerts greater influence on visual processing in the psychedelic state, thereby defining its hallucinatory quality. LSD's marked effects on the visual cortex did not significantly correlate with the drug's other characteristic effects on consciousness, however. Rather, decreased connectivity between the parahippocampus and retrosplenial cortex (RSC) correlated strongly with ratings of "ego-dissolution" and "altered meaning," implying the importance of this particular circuit for the maintenance of "self" or "ego" and its processing of "meaning." Strong relationships were also found between the different imaging metrics, enabling firmer inferences to be made about their functional significance. This uniquely comprehensive examination of the LSD state represents an important advance in scientific research with psychedelic drugs at a time of growing interest in their scientific and therapeutic value. The present results contribute important new insights into the characteristic hallucinatory and consciousness-altering properties of psychedelics that inform on how they can model certain pathological states and potentially treat others.

  20. Methodology for measurement in schools and kindergartens: experiences

    International Nuclear Information System (INIS)

    Fotjikova, I.; Navratilova Rovenska, K.

    2015-01-01

    In more than 1500 schools and preschool facilities, long-term radon measurement was carried out in the last 3 y. The negative effect of thermal retrofitting on the resulting long-term radon averages is evident. In some of the facilities, low ventilation rates and correspondingly high radon levels were found, so it was recommended to change ventilation habits. However, some of the facilities had high radon levels due to its ingress from soil gas. Technical measures should be undertaken to reduce radon exposure in this case. The paper presents the long-term experiences with the two-stage measurement methodology for investigation of radon levels in school and preschool facilities and its possible improvements. (authors)

  1. Medium energy measurements of N-N parameters

    International Nuclear Information System (INIS)

    Ambrose, D.; Bachman, M.; Coffey, P.; Glass, G.; Jobst, B.; McNaughton, Kok Heong; Nguyen, Chau; Riley, P.J.

    1993-01-01

    Most of the effort was devoted to the study of nucleon-nucleon interactions, specifically, spin transfer measurements in np elastic scattering at LAMPF, pp elastic differential cross section measurements at LAMPF, and single-pion production in np scattering. Differential cross sections and analyzing powers are shown for np→ppπ - interactions. A new search for rare K L 0 decays to μe, μμ, and ee is being undertaken. Collaborative work has been begun on a very large, complex collider detector STAR (Solenoidal Tracker At RHIC). STAR is envisioned as a combination of a silicon vertex tracker, a time projection chamber, a set of trigger scintillators, and time-of-flight counters. It would allow measurements of spin dependence at p T above 10 GeV/c

  2. Measurement of thermal properties of soil and concrete samples

    DEFF Research Database (Denmark)

    Pagola, Maria Alberdi; Jensen, Rasmus Lund; Madsen, Søren

    This document aims to present the laboratory work undertaken to analyse the thermal properties of the soil at two test sites in Denmark and the concrete produced by Centrum Pæle A/S, used to produce the pile heat exchangers studied in the present PhD project. The tasks have been carried out between...... “Thermal response testing of precast pile heat exchangers: fieldwork report” by (Alberdi-Pagola et al., 2017). The report is organized as follows: first, the measurement methods and the test procedures are described. Second, the soils at both test sites are described, together with the measurements. Third......, the measurements of the properties of the concrete are treated. The work is extended in appendixes....

  3. Coming up short on nonfinancial performance measurement.

    Science.gov (United States)

    Ittner, Christopher D; Larcker, David F

    2003-11-01

    Companies in increasing numbers are measuring customer loyalty, employee satisfaction, and other nonfinancial areas of performance that they believe affect profitability. But they've failed to relate these measures to their strategic goals or establish a connection between activities undertaken and financial outcomes achieved. Failure to make such connections has led many companies to misdirect their investments and reward ineffective managers. Extensive field research now shows that businesses make some common mistakes when choosing, analyzing, and acting on their nonfinancial measures. Among these mistakes: They set the wrong performance targets because they focus too much on short-term financial results, and they use metrics that lack strong statistical validity and reliability. As a result, the companies can't demonstrate that improvements in nonfinancial measures actually affect their financial results. The authors lay out a series of steps that will allow companies to realize the genuine promise of nonfinancial performance measures. First, develop a model that proposes a causal relationship between the chosen nonfinancial drivers of strategic success and specific outcomes. Next, take careful inventory of all the data within your company. Then use established statistical methods for validating the assumed relationships and continue to test the model as market conditions evolve. Finally, base action plans on analysis of your findings, and determine whether those plans and their investments actually produce the desired results. Nonfinancial measures will offer little guidance unless you use a process for choosing and analyzing them that relies on sophisticated quantitative and qualitative inquiries into the factors actually contributing to economic results.

  4. Absolute measurement of the responses of small lithium glass scintillators to gamma radiation

    International Nuclear Information System (INIS)

    Dalton, A.W.

    1987-04-01

    The absolute scintillation efficiency and intrinsic resolution of lithium glass scintillators for electron excitation have been determined over a range of electron energies, lithium concentrations and lithium enrichments. Measurements of these response characteristics form part of a study on the possible use of such glasses for the determination of tritium breeding in fusion reactor blanket experiments. The measurements were undertaken to establish a basis for extracting the information relating to tritium production reactions from the background signals induced within the glass scintillators by the neutron/gamma fields of a fusion reactor blanket. Criteria for the selection of glasses most suitable for tritium breeding measurements are discussed in tems of their observed responses

  5. Virtually naked: virtual environment reveals sex-dependent nature of skin disclosure.

    Directory of Open Access Journals (Sweden)

    Anna M Lomanowska

    Full Text Available The human tendency to reveal or cover naked skin reflects a competition between the individual propensity for social interactions related to sexual appeal and interpersonal touch versus climatic, environmental, physical, and cultural constraints. However, due to the ubiquitous nature of these constraints, isolating on a large scale the spontaneous human tendency to reveal naked skin has remained impossible. Using the online 3-dimensional virtual world of Second Life, we examined spontaneous human skin-covering behavior unhindered by real-world climatic, environmental, and physical variables. Analysis of hundreds of avatars revealed that virtual females disclose substantially more naked skin than virtual males. This phenomenon was not related to avatar hypersexualization as evaluated by measurement of sexually dimorphic body proportions. Furthermore, analysis of skin-covering behavior of a population of culturally homogeneous avatars indicated that the propensity of female avatars to reveal naked skin persisted despite explicit cultural norms promoting less revealing attire. These findings have implications for further understanding how sex-specific aspects of skin disclosure influence human social interactions in both virtual and real settings.

  6. Gene expression profiling in equine polysaccharide storage myopathy revealed inflammation, glycogenesis inhibition, hypoxia and mitochondrial dysfunctions

    Directory of Open Access Journals (Sweden)

    Benech Philippe

    2009-08-01

    Full Text Available Abstract Background Several cases of myopathies have been observed in the horse Norman Cob breed. Muscle histology examinations revealed that some families suffer from a polysaccharide storage myopathy (PSSM. It is assumed that a gene expression signature related to PSSM should be observed at the transcriptional level because the glycogen storage disease could also be linked to other dysfunctions in gene regulation. Thus, the functional genomic approach could be conducted in order to provide new knowledge about the metabolic disorders related to PSSM. We propose exploring the PSSM muscle fiber metabolic disorders by measuring gene expression in relationship with the histological phenotype. Results Genotypying analysis of GYS1 mutation revealed 2 homozygous (AA and 5 heterozygous (GA PSSM horses. In the PSSM muscles, histological data revealed PAS positive amylase resistant abnormal polysaccharides, inflammation, necrosis, and lipomatosis and active regeneration of fibers. Ultrastructural evaluation revealed a decrease of mitochondrial number and structural disorders. Extensive accumulation of an abnormal polysaccharide displaced and partially replaced mitochondria and myofibrils. The severity of the disease was higher in the two homozygous PSSM horses. Gene expression analysis revealed 129 genes significantly modulated (p Conclusion The main disorders observed in PSSM muscles could be related to mitochondrial dysfunctions, glycogenesis inhibition and the chronic hypoxia of the PSSM muscles.

  7. Measuring online social bubbles

    Directory of Open Access Journals (Sweden)

    Dimitar Nikolov

    2015-12-01

    Full Text Available Social media have become a prevalent channel to access information, spread ideas, and influence opinions. However, it has been suggested that social and algorithmic filtering may cause exposure to less diverse points of view. Here we quantitatively measure this kind of social bias at the collective level by mining a massive datasets of web clicks. Our analysis shows that collectively, people access information from a significantly narrower spectrum of sources through social media and email, compared to a search baseline. The significance of this finding for individual exposure is revealed by investigating the relationship between the diversity of information sources experienced by users at both the collective and individual levels in two datasets where individual users can be analyzed—Twitter posts and search logs. There is a strong correlation between collective and individual diversity, supporting the notion that when we use social media we find ourselves inside “social bubbles.” Our results could lead to a deeper understanding of how technology biases our exposure to new information.

  8. [18F]DPA 714 PET Imaging Reveals Global Neuroinflammation in Zika Virus Infected Mice

    Science.gov (United States)

    2017-09-12

    antibodies to disrupt IFN signaling were evaluated at early, middle, and late stages of infection by PET imaging using [18F]DPA-714. To control for effects ...produce a mild yet transient neuroinflammatory effect measureable by [18F]DPA-714 PET imaging. Importantly, 5A3 treatment in the absence of ZIKV had...18F]DPA-714 PET Imaging Reveals Global Neuroinflammation in Zika Virus- Infected Mice Kyle Kuszpit1†, Bradley S. Hollidge2†, Xiankun Zeng3, Robert

  9. Can microlensing fold caustics reveal a second stellar limb-darkening coefficient?

    OpenAIRE

    Dominik, M.

    2004-01-01

    Dense high-precision photometry of microlensed stars during a fold-caustic passage can be used to reveal their intensity profiles from which the temperature of the stellar atmosphere as function of fractional radius can be derived. While the capabilities of current microlensing follow-up campaigns such as PLANET allow a precise measurement of linear limb-darkening coefficients, the residual signal of a second coefficient characterizing square-root limb darkening is ~ 25 times smaller which pr...

  10. Paraneoplastic syndromes revealing ovarian teratoma in young and ...

    African Journals Online (AJOL)

    Paraneoplastic syndromes revealing ovarian teratoma in young and menopausal women: report of two cases. Majdouline Boujoual, Ihsan Hakimi, Farid Kassidi, Youssef Akhoudad, Nawal Sahel, Adil Rkiouak, Mohamed Allaoui, Hafsa Chahdi, Mohamed Oukabli, Jaouad Kouach, Driss Rahali Moussaoui, Mohamed ...

  11. Solid–liquid equilibria measurements for binary systems comprising (butyric acid + propionic or pentanoic acid) and (heptanoic acid + propionic or butyric or pentanoic or hexanoic acid)

    International Nuclear Information System (INIS)

    Tadie, Margreth; Bahadur, Indra; Reddy, Prashant; Ngema, Peterson Thokozani; Naidoo, Paramespri; Deenadayalu, Nirmala; Ramjugernath, Deresh

    2013-01-01

    Highlights: ► Binary SLE measurement for butyric acid + {propionic or pentanoic acid}. ► Binary SLE measurements for heptanoic acid + {propionic or butyric or pentanoic or hexanoic acid}. ► Measurements undertaken using a synthetic method using two new apparati. - Abstract: Solid–liquid equilibria (SLE) measurements have been undertaken for carboxylic acid systems comprising (butyric acid + propionic or pentanoic acid) and (heptanoic acid + propionic or butyric or pentanoic or hexanoic acid) via a synthetic method using two complementary pieces of equipment. The measurements have been obtained at atmospheric pressure and over the temperature range of (225.6 to 270.7) K. All the acid mixtures exhibit a eutectic point in their respective phase diagrams, which have been determined experimentally. The estimated maximum uncertainties in the reported temperatures and compositions are ±1 K and ±0.0006 mole fraction, respectively. The experimental data have been satisfactorily correlated with the Wilson and NRTL activity coefficient models.

  12. Ultrasonic fetal size measurements in Brisbane, Australia

    International Nuclear Information System (INIS)

    Schluter, P.J.; Pritchard, G.; Gill, M.A.

    2004-01-01

    The purpose of this paper was to construct population-specific charts of fetal biometry for 11-41 weeks gestation in relation to known gestational age from a large population of normal Australian pregnancies when examination is performed to a standard protocol by experienced operators. All consenting eligible women attending a large Brisbane clinic between January 1993 and April 2003 were recruited. Menstrual history was taken prior to examination. Measurements were performed to a standard protocol. Prospective assessment was made about the association between gestational age from the last menstrual period and biometry. Exclusion principles were applied. Statistical analyses were performed using polynomial regression models and thorough diagnostic checks were undertaken. Included within the study were separate scans for 20 555 pregnancies from 17 660 women. Equations, means and 95th reference intervals were derived and reported for the following sonographic measurements: biparietal diameter (BPD), head circumference (HC), abdominal circumference (AC) and femur length (FL). Population-specific regression equations for BPD, HC, AC and FL have been proposed for Australian pregnancies. Once validated by others, we believe they will warrant consideration for adoption by the Australasian Society for Ultrasound in Medicine. Copyright (2004) Blackwell Publishing Asia Pty Ltd

  13. Contingent convertible bonds as countercyclical capital measures

    Directory of Open Access Journals (Sweden)

    Francois Liebenberg

    2017-06-01

    Aim: The effectiveness of the CCB during contractions is not obvious. Contingent convertible (CoCo bonds – which are bond-like until triggered by a deterioration of a prescribed capital metric, at which point they convert into a form of equity – are explored as a supplementary countercyclical capital measure for such periods to establish whether or not they function effectively. Setting: The analysis is undertaken using global bank CoCo data, and then applied to South African banks. Methods: The Hodrick Prescott filter was applied to empirical historical data. Results: The CCB functions as a good countercyclical capital measure in times of economic expansion by absorbing losses and stabilising the capital base through equity issuance. Conclusion: The issuance of CoCo bonds – if their trigger mechanisms are designed correctly – may prove helpful to banks and the broader financial sector in times of economic contraction through the countercyclical capital properties that manifest through CoCo bonds under these economic conditions.

  14. Quantum learning algorithms for quantum measurements

    International Nuclear Information System (INIS)

    Bisio, Alessandro; D'Ariano, Giacomo Mauro; Perinotti, Paolo; Sedlak, Michal

    2011-01-01

    We study quantum learning algorithms for quantum measurements. The optimal learning algorithm is derived for arbitrary von Neumann measurements in the case of training with one or two examples. The analysis of the case of three examples reveals that, differently from the learning of unitary gates, the optimal algorithm for learning of quantum measurements cannot be parallelized, and requires quantum memories for the storage of information. -- Highlights: → Optimal learning algorithm for von Neumann measurements. → From 2 copies to 1 copy: the optimal strategy is parallel. → From 3 copies to 1 copy: the optimal strategy must be non-parallel.

  15. Single cell transcriptional analysis reveals novel innate immune cell types

    Directory of Open Access Journals (Sweden)

    Linda E. Kippner

    2014-06-01

    Full Text Available Single-cell analysis has the potential to provide us with a host of new knowledge about biological systems, but it comes with the challenge of correctly interpreting the biological information. While emerging techniques have made it possible to measure inter-cellular variability at the transcriptome level, no consensus yet exists on the most appropriate method of data analysis of such single cell data. Methods for analysis of transcriptional data at the population level are well established but are not well suited to single cell analysis due to their dependence on population averages. In order to address this question, we have systematically tested combinations of methods for primary data analysis on single cell transcription data generated from two types of primary immune cells, neutrophils and T lymphocytes. Cells were obtained from healthy individuals, and single cell transcript expression data was obtained by a combination of single cell sorting and nanoscale quantitative real time PCR (qRT-PCR for markers of cell type, intracellular signaling, and immune functionality. Gene expression analysis was focused on hierarchical clustering to determine the existence of cellular subgroups within the populations. Nine combinations of criteria for data exclusion and normalization were tested and evaluated. Bimodality in gene expression indicated the presence of cellular subgroups which were also revealed by data clustering. We observed evidence for two clearly defined cellular subtypes in the neutrophil populations and at least two in the T lymphocyte populations. When normalizing the data by different methods, we observed varying outcomes with corresponding interpretations of the biological characteristics of the cell populations. Normalization of the data by linear standardization taking into account technical effects such as plate effects, resulted in interpretations that most closely matched biological expectations. Single cell transcription

  16. The neurobiology of offensive aggression: Revealing a modular view.

    Science.gov (United States)

    de Boer, S F; Olivier, B; Veening, J; Koolhaas, J M

    2015-07-01

    Experimental studies aimed at understanding the neurobiology of aggression started in the early 20th century, and by employing increasingly sophisticated tools of functional neuroanatomy (i.e., from electric/chemical lesion and stimulation techniques to neurochemical mapping and manipulations) have provided the important framework for the functional brain circuit organization of aggressive behaviors. Recently, newly emerging technologies for mapping,measuring and manipulating neural circuitry at the level of molecular and genetically defined neuronal subtypes promise to further delineate the precise neural microcircuits mediating the initiation and termination of aggressive behavior, and characterize its dynamic neuromolecular functioning. This paper will review some of the behavioral, neuroanatomical and neurochemical evidence in support of a modular view of the neurobiology of offensive aggressive behavior. Although aggressive behavior likely arises from a specific concerted activity within a distributed neural network across multiple brain regions, emerging opto- and pharmacogenetic neuronal manipulation studies make it clear that manipulation of molecularly-defined neurons within a single node of this global interconnected network seems to be both necessary and sufficient to evoke aggressive attacks. However, the evidence so far also indicates that in addition to behavior-specific neurons there are neuronal systems that should be considered as more general behavioral control modules. The answer to the question of behavioral specificity of brain structures at the level of individual neurons requires a change of the traditional experimental setup. Studies using c-fos expression mapping usually compare the activation patterns induced by for example aggression with a home cage control. However, to reveal the behavioral specificity of this neuronal activation pattern, a comparison with other social and non-social related behaviors such as mating, defensive burying

  17. Black Hole Spin Measurement Uncertainty

    Science.gov (United States)

    Salvesen, Greg; Begelman, Mitchell C.

    2018-01-01

    Angular momentum, or spin, is one of only two fundamental properties of astrophysical black holes, and measuring its value has numerous applications. For instance, obtaining reliable spin measurements could constrain the growth history of supermassive black holes and reveal whether relativistic jets are powered by tapping into the black hole spin reservoir. The two well-established techniques for measuring black hole spin can both be applied to X-ray binaries, but are in disagreement for cases of non-maximal spin. This discrepancy must be resolved if either technique is to be deemed robust. We show that the technique based on disc continuum fitting is sensitive to uncertainties regarding the disc atmosphere, which are observationally unconstrained. By incorporating reasonable uncertainties into black hole spin probability density functions, we demonstrate that the spin measured by disc continuum fitting can become highly uncertain. Future work toward understanding how the observed disc continuum is altered by atmospheric physics, particularly magnetic fields, will further strengthen black hole spin measurement techniques.

  18. Gene expression profiling in equine polysaccharide storage myopathy revealed inflammation, glycogenesis inhibition, hypoxia and mitochondrial dysfunctions.

    Science.gov (United States)

    Barrey, Eric; Mucher, Elodie; Jeansoule, Nicolas; Larcher, Thibaut; Guigand, Lydie; Herszberg, Bérénice; Chaffaux, Stéphane; Guérin, Gérard; Mata, Xavier; Benech, Philippe; Canale, Marielle; Alibert, Olivier; Maltere, Péguy; Gidrol, Xavier

    2009-08-07

    Several cases of myopathies have been observed in the horse Norman Cob breed. Muscle histology examinations revealed that some families suffer from a polysaccharide storage myopathy (PSSM). It is assumed that a gene expression signature related to PSSM should be observed at the transcriptional level because the glycogen storage disease could also be linked to other dysfunctions in gene regulation. Thus, the functional genomic approach could be conducted in order to provide new knowledge about the metabolic disorders related to PSSM. We propose exploring the PSSM muscle fiber metabolic disorders by measuring gene expression in relationship with the histological phenotype. Genotypying analysis of GYS1 mutation revealed 2 homozygous (AA) and 5 heterozygous (GA) PSSM horses. In the PSSM muscles, histological data revealed PAS positive amylase resistant abnormal polysaccharides, inflammation, necrosis, and lipomatosis and active regeneration of fibers. Ultrastructural evaluation revealed a decrease of mitochondrial number and structural disorders. Extensive accumulation of an abnormal polysaccharide displaced and partially replaced mitochondria and myofibrils. The severity of the disease was higher in the two homozygous PSSM horses.Gene expression analysis revealed 129 genes significantly modulated (p < 0.05). The following genes were up-regulated over 2 fold: IL18, CTSS, LUM, CD44, FN1, GST01. The most down-regulated genes were the following: mitochondrial tRNA, SLC2A2, PRKCalpha, VEGFalpha. Data mining analysis showed that protein synthesis, apoptosis, cellular movement, growth and proliferation were the main cellular functions significantly associated with the modulated genes (p < 0.05). Several up-regulated genes, especially IL18, revealed a severe muscular inflammation in PSSM muscles. The up-regulation of glycogen synthase kinase-3 (GSK3beta) under its active form could be responsible for glycogen synthase (GYS1) inhibition and hypoxia-inducible factor (HIF1alpha

  19. Structure reveals regulatory mechanisms of a MaoC-like hydratase from Phytophthora capsici involved in biosynthesis of polyhydroxyalkanoates (PHAs.

    Directory of Open Access Journals (Sweden)

    Huizheng Wang

    Full Text Available Polyhydroxyalkanoates (PHAs have attracted increasing attention as "green plastic" due to their biodegradable, biocompatible, thermoplastic, and mechanical properties, and considerable research has been undertaken to develop low cost/high efficiency processes for the production of PHAs. MaoC-like hydratase (MaoC, which belongs to (R-hydratase involved in linking the β-oxidation and the PHA biosynthetic pathways, has been identified recently. Understanding the regulatory mechanisms of (R-hydratase catalysis is critical for efficient production of PHAs that promise synthesis an environment-friendly plastic.We have determined the crystal structure of a new MaoC recognized from Phytophthora capsici. The crystal structure of the enzyme was solved at 2.00 Å resolution. The structure shows that MaoC has a canonical (R-hydratase fold with an N-domain and a C-domain. Supporting its dimerization observed in structure, MaoC forms a stable homodimer in solution. Mutations that disrupt the dimeric MaoC result in a complete loss of activity toward crotonyl-CoA, indicating that dimerization is required for the enzymatic activity of MaoC. Importantly, structure comparison reveals that a loop unique to MaoC interacts with an α-helix that harbors the catalytic residues of MaoC. Deletion of the loop enhances the enzymatic activity of MaoC, suggesting its inhibitory role in regulating the activity of MaoC.The data in our study reveal the regulatory mechanism of an (R-hydratase, providing information on enzyme engineering to produce low cost PHAs.

  20. COMPARISON OF PREOPERATIVE NONINVASIVE AND INTRAOPERATIVE MEASUREMENTS OF AORTIC ANNULUS

    Directory of Open Access Journals (Sweden)

    Manish Hinduja

    2016-10-01

    Full Text Available BACKGROUND Precise preoperative assessment of aortic annulus diameter is essential for sizing of aortic valve especially in patients planned for transcatheter aortic valve replacement. Computed Tomographic (CT and echocardiographic measurements of the aortic annulus vary because of elliptical shape of aortic annulus. This study was undertaken to compare the measurement of aortic annulus intraoperatively with preoperative noninvasive methods in patients undergoing aortic valve replacement. MATERIALS AND METHODS Aortic annulus diameter was measured with cardiac CT and Transesophageal Echocardiography (TEE prior to open aortic valve replacement in 30 patients with aortic valve stenosis. In CT, aortic annulus dimensions were measured in coronal plane, sagittal oblique plane and by planimetry. Both 2-dimensional and 3-dimensional TEE were used. These were compared with intraoperative measurements done by valve sizers and Hegar dilators. Pearson analysis was applied to test for degree of correlation. RESULTS CT in coronal and sagittal oblique plane tends to overestimate the diameter of aortic annulus when compared with intraoperative measurements (coefficient of relation, r = 0.798 and 0.749, respectively. CT measurements in single oblique plane showed a weaker correlation with intraoperative measurements than 3D TEE and 2D TEE (r = 0.917 and 0.898, respectively. However, CT measurements by planimetry method were most correlating with the intraoperative measurements (r = 0.951. CONCLUSION Noninvasive investigations with 3-dimensional views (CT-based measurement employing calculated average diameter assessment by planimetry and 3-dimensional TEE showed better correlation with intraoperative measurement of aortic annulus. CT-based aortic annulus measurement by planimetry seems to provide adequate dimensions most similar to operative measurements.

  1. On the measurement of comparative advantage

    NARCIS (Netherlands)

    Hoen, A.R.; Oosterhaven, J.

    This paper shows-that the standard measure of revealed comparative advantage (RCA), ranging from 0 to infinity, has problematic properties. Due to its multiplicative specification, it has a moving mean larger than its expected value of 1, while its distribution strongly depends on the number of

  2. Measuring Teaching Quality in Several European Countries

    Science.gov (United States)

    van de Grift, Wim J. C. M.

    2014-01-01

    Teaching quality has been observed in large representative samples from Flanders (Belgium), Lower Saxony (Germany), the Slovak Republic, and The Netherlands. This study reveals that measures of "creating a safe and stimulating climate", "clear and activating instruction", and "teaching learning strategies" were…

  3. Genomic Analysis of Hospital Plumbing Reveals Diverse Reservoir of Bacterial Plasmids Conferring Carbapenem Resistance.

    Science.gov (United States)

    Weingarten, Rebecca A; Johnson, Ryan C; Conlan, Sean; Ramsburg, Amanda M; Dekker, John P; Lau, Anna F; Khil, Pavel; Odom, Robin T; Deming, Clay; Park, Morgan; Thomas, Pamela J; Henderson, David K; Palmore, Tara N; Segre, Julia A; Frank, Karen M

    2018-02-06

    mortality associated with these resistant Gram-negative bacteria. Horizontal plasmid transfer spreads the resistance mechanism to new bacteria, and understanding the plasmid ecology of the hospital environment can assist in the design of control strategies to prevent nosocomial infections. A 5-year genomic and epidemiological survey was undertaken to study the CPOs in the patient-accessible environment, as well as in the plumbing system removed from the patient. This comprehensive survey revealed a vast, unappreciated reservoir of CPOs in wastewater, which was in contrast to the low positivity rate in both the patient population and the patient-accessible environment. While there were few patient-environmental isolate associations, there were plasmid backbones common to both populations. These results are relevant to all hospitals for which CPO colonization may not yet be defined through extensive surveillance.

  4. PCNA immunoreactivity revealing normal proliferative activity in the brain of an adult Elasmobranch, Torpedo marmorata.

    Science.gov (United States)

    Margotta, Vito

    2007-01-01

    The brain of adult heterothermic vertebrates can be already provided of quiescent cells, scattered ("matrix cells") and/or clustered ("matrix areas"). These typical cells, in some regions located at or near ventricular surfaces and at peri-ependymal layers, in other territories populating their framework, maintain some embryonic properties and are responsible of normal or variously experimentally induced proliferative activities. On these topics there are a great number of reports concerning Teleostean Osteichthyes, Urodele and Anuran Amphibians, Lacertilian Reptiles. At the contrary, only few are the contributions regarding the Petromyzontidae. Involving an immunocytochemical marker, the Proliferating Cell Nuclear Antigen (PCNA), revealing proliferative events, in the last years we have undertaken a reappraisal focused on these encephalic performances in normal adult poikilothermal vertebrates. To provide a valid comparison between our results and the literature data, our choice of the specimens was based on the desire to employ organisms belonging to the same or phylogenetically close species used by previous Authors in similar studies. In our immunocytochemical panorama there is a substantial agreement between our contributions and bibliographic references concerning natural encephalic proliferative phenomena in these vertebrates. At this point of our study, the last missing piece was represented by the Chondrichthyes about which the literature data are lacking. In order to fill this gap, the aim of the present research is to investigate, involving the same PCNA test, whether proliferative events also persist in the brain of adult cartilaginous fishes. The immunostaining images obtained in the Elasmo branch Torpedo marmorata, well-known for the emission of high electrical discharges, exhibit undifferentiated cells in relationship with the ependymal epithelium lining the cavities of all cerebral districts; some other neuroblasts are scattered in the mesencephalic

  5. Deep sequencing analysis of the developing mouse brain reveals a novel microRNA

    Directory of Open Access Journals (Sweden)

    Piltz Sandra

    2011-04-01

    Full Text Available Abstract Background MicroRNAs (miRNAs are small non-coding RNAs that can exert multilevel inhibition/repression at a post-transcriptional or protein synthesis level during disease or development. Characterisation of miRNAs in adult mammalian brains by deep sequencing has been reported previously. However, to date, no small RNA profiling of the developing brain has been undertaken using this method. We have performed deep sequencing and small RNA analysis of a developing (E15.5 mouse brain. Results We identified the expression of 294 known miRNAs in the E15.5 developing mouse brain, which were mostly represented by let-7 family and other brain-specific miRNAs such as miR-9 and miR-124. We also discovered 4 putative 22-23 nt miRNAs: mm_br_e15_1181, mm_br_e15_279920, mm_br_e15_96719 and mm_br_e15_294354 each with a 70-76 nt predicted pre-miRNA. We validated the 4 putative miRNAs and further characterised one of them, mm_br_e15_1181, throughout embryogenesis. Mm_br_e15_1181 biogenesis was Dicer1-dependent and was expressed in E3.5 blastocysts and E7 whole embryos. Embryo-wide expression patterns were observed at E9.5 and E11.5 followed by a near complete loss of expression by E13.5, with expression restricted to a specialised layer of cells within the developing and early postnatal brain. Mm_br_e15_1181 was upregulated during neurodifferentiation of P19 teratocarcinoma cells. This novel miRNA has been identified as miR-3099. Conclusions We have generated and analysed the first deep sequencing dataset of small RNA sequences of the developing mouse brain. The analysis revealed a novel miRNA, miR-3099, with potential regulatory effects on early embryogenesis, and involvement in neuronal cell differentiation/function in the brain during late embryonic and early neonatal development.

  6. Measuring discursive influence across scholarship.

    Science.gov (United States)

    Gerow, Aaron; Hu, Yuening; Boyd-Graber, Jordan; Blei, David M; Evans, James A

    2018-03-27

    Assessing scholarly influence is critical for understanding the collective system of scholarship and the history of academic inquiry. Influence is multifaceted, and citations reveal only part of it. Citation counts exhibit preferential attachment and follow a rigid "news cycle" that can miss sustained and indirect forms of influence. Building on dynamic topic models that track distributional shifts in discourse over time, we introduce a variant that incorporates features, such as authorship, affiliation, and publication venue, to assess how these contexts interact with content to shape future scholarship. We perform in-depth analyses on collections of physics research (500,000 abstracts; 102 years) and scholarship generally (JSTOR repository: 2 million full-text articles; 130 years). Our measure of document influence helps predict citations and shows how outcomes, such as winning a Nobel Prize or affiliation with a highly ranked institution, boost influence. Analysis of citations alongside discursive influence reveals that citations tend to credit authors who persist in their fields over time and discount credit for works that are influential over many topics or are "ahead of their time." In this way, our measures provide a way to acknowledge diverse contributions that take longer and travel farther to achieve scholarly appreciation, enabling us to correct citation biases and enhance sensitivity to the full spectrum of scholarly impact. Copyright © 2018 the Author(s). Published by PNAS.

  7. UTV Expansion Pack: Special-Purpose Rank-Revealing Algorithms

    DEFF Research Database (Denmark)

    Fierro, Ricardo D.; Hansen, Per Christian

    2005-01-01

    This collection of Matlab 7.0 software supplements and complements the package UTV Tools from 1999, and includes implementations of special-purpose rank-revealing algorithms developed since the publication of the original package. We provide algorithms for computing and modifying symmetric rank-r...... values of a sparse or structured matrix. These new algorithms have applications in signal processing, optimization and LSI information retrieval.......This collection of Matlab 7.0 software supplements and complements the package UTV Tools from 1999, and includes implementations of special-purpose rank-revealing algorithms developed since the publication of the original package. We provide algorithms for computing and modifying symmetric rank......-revealing VSV decompositions, we expand the algorithms for the ULLV decomposition of a matrix pair to handle interference-type problems with a rank-deficient covariance matrix, and we provide a robust and reliable Lanczos algorithm which - despite its simplicity - is able to capture all the dominant singular...

  8. Activity screening of environmental metagenomic libraries reveals novel carboxylesterase families

    Science.gov (United States)

    Popovic, Ana; Hai, Tran; Tchigvintsev, Anatoly; Hajighasemi, Mahbod; Nocek, Boguslaw; Khusnutdinova, Anna N.; Brown, Greg; Glinos, Julia; Flick, Robert; Skarina, Tatiana; Chernikova, Tatyana N.; Yim, Veronica; Brüls, Thomas; Paslier, Denis Le; Yakimov, Michail M.; Joachimiak, Andrzej; Ferrer, Manuel; Golyshina, Olga V.; Savchenko, Alexei; Golyshin, Peter N.; Yakunin, Alexander F.

    2017-01-01

    Metagenomics has made accessible an enormous reserve of global biochemical diversity. To tap into this vast resource of novel enzymes, we have screened over one million clones from metagenome DNA libraries derived from sixteen different environments for carboxylesterase activity and identified 714 positive hits. We have validated the esterase activity of 80 selected genes, which belong to 17 different protein families including unknown and cyclase-like proteins. Three metagenomic enzymes exhibited lipase activity, and seven proteins showed polyester depolymerization activity against polylactic acid and polycaprolactone. Detailed biochemical characterization of four new enzymes revealed their substrate preference, whereas their catalytic residues were identified using site-directed mutagenesis. The crystal structure of the metal-ion dependent esterase MGS0169 from the amidohydrolase superfamily revealed a novel active site with a bound unknown ligand. Thus, activity-centered metagenomics has revealed diverse enzymes and novel families of microbial carboxylesterases, whose activity could not have been predicted using bioinformatics tools. PMID:28272521

  9. The Principle of Advertising as a Measure of the Essential Control of State Acts

    Directory of Open Access Journals (Sweden)

    Osvaldo Resende Neto Resende Neto

    2016-10-01

    Full Text Available Brazilian citizen has seen several scandals related to corruption, leading to an outcry for the adoption of effective measures to combat impunity. Emerges the importance of the principle of publicity as an important tool for democratic control, extending far beyond the limits of public administration in management and procedural situations. The undertaken goal here is to outline the importance of advertising in the effectiveness of legal measures for the prevention and repression of misuse of the exchequer. Using the inductive method, it was conducted a systematic research on national bibliography, exploring existing and revoked legislation on the subject.

  10. Fundamental questions before recording or measuring functioning and disability.

    Science.gov (United States)

    Madden, Ros; Fortune, Nicola; Cheeseman, Danielle; Mpofu, Elias; Bundy, Anita

    2013-06-01

    This paper seeks to contribute to thoughtful description, recording and measurement of functioning, by discussing some fundamental questions to consider before starting, framed as: why, what, how and who. Generic literature on measurement methods and the more specialised literature on application of the ICF over the last decade inform the consideration of these questions. The context of recording or measurement is examined, including the moral and legal framework of the UN Convention on the Rights of Persons with Disabilities (UNCRPD) and the technical framework of the International Classification of Functioning, Disability and Health (ICF). Whatever the setting in which describing, recording or measuring is being undertaken - in policy development, service planning and management, clinical management or population health monitoring - determining the purpose is the key starting point. Purpose (why) frames the consideration of content (what), method (how) and source (who). Many generic measurement methods can be applied in the disability field, but there are challenges particular to the field. The perspectives of people with disabilities and "patients" require consideration, especially with the trend to person-centred care and the social justice principles emanating from the UNCRPD. Considering these basic questions is a pre-requisite to meaningful recording and measurement of functioning and disability. Future challenges include: incorporating environmental factors into measurement; setting thresholds on the disability spectrum; and combining the views of the person concerned with those of various professionals.

  11. Burned-out seminoma revealed by solitary rib bone metastasis

    Energy Technology Data Exchange (ETDEWEB)

    Nishisho, Toshihiko; Miyagi, Ryo; Sairyo, Koichi [Tokushima University Graduate School, Department of Orthopedics, Institute of Biomedical Sciences, Tokushima-city, Tokushima (Japan); Sakaki, Mika [Saitama Medical University International Medical Center, Department of Pathology, Hidaka-city, Saitama (Japan); Takao, Shoichiro [Tokushima University Graduate School, Department of Radiology, Institute of Biomedical Sciences, Tokushima-city, Tokushima (Japan)

    2017-10-15

    Burned-out tumor is a rare phenomenon in which a testicular tumor regresses in the primary lesion and progresses in a metastatic lesion. We report the case of a 30-year-old male with burned-out seminoma revealed by open biopsy of solitary 10th rib bone metastasis. He underwent inguinal orchiectomy, which revealed hyalinization, indicating a spontaneously regressed testicular tumor. Chemotherapy for seminoma was administered in three cycles of bleomycin + etoposide + cisplatin therapy. The chemotherapy was effective, and wide resection of the rib was subsequently performed. No postoperative chemotherapy was performed, and there has been no evidence of recurrence for 3 years postoperatively. (orig.)

  12. The organizational measurement manual

    National Research Council Canada - National Science Library

    Wealleans, David

    2001-01-01

    ... Relationship of process to strategic measurements Summary 37 36Contents 19/10/2000 1:23 pm Page vi vi THE ORGANIZATIONAL MEASUREMENT MANUAL 4 PART 2 ESTABLISHING A PROCESS MEASUREMENT PROGRAMME...

  13. Measurements on Hearing

    DEFF Research Database (Denmark)

    Poulsen, Torben

    1996-01-01

    Background material for measurements of hearing for grammar school pupils. The note gives the necessary background for the exercise 'Measurement on Hearing'. The topics comprise sound and decibel, the ear, basic psychoacoustics, hearing threshold, audiometric measurement methods, speech and speech...

  14. Mobile Instruments Measure Atmospheric Pollutants

    Science.gov (United States)

    2009-01-01

    As a part of NASA's active research of the Earth s atmosphere, which has included missions such as the Atmospheric Laboratory of Applications and Science (ATLAS, launched in 1992) and the Total Ozone Mapping Spectrometer (TOMS, launched on the Earth Probe satellite in 1996), the Agency also performs ground-based air pollution research. The ability to measure trace amounts of airborne pollutants precisely and quickly is important for determining natural patterns and human effects on global warming and air pollution, but until recent advances in field-grade spectroscopic instrumentation, this rapid, accurate data collection was limited and extremely difficult. In order to understand causes of climate change and airborne pollution, NASA has supported the development of compact, low power, rapid response instruments operating in the mid-infrared "molecular fingerprint" portion of the electromagnetic spectrum. These instruments, which measure atmospheric trace gases and airborne particles, can be deployed in mobile laboratories - customized ground vehicles, typically - to map distributions of pollutants in real time. The instruments must be rugged enough to operate rapidly and accurately, despite frequent jostling that can misalign, damage, or disconnect sensitive components. By measuring quickly while moving through an environment, a mobile laboratory can correlate data and geographic points, revealing patterns in the environment s pollutants. Rapid pollutant measurements also enable direct determination of pollutant sources and sinks (mechanisms that remove greenhouse gases and pollutants), providing information critical to understanding and managing atmospheric greenhouse gas and air pollutant concentrations.

  15. Measuring Test Measurement Error: A General Approach

    Science.gov (United States)

    Boyd, Donald; Lankford, Hamilton; Loeb, Susanna; Wyckoff, James

    2013-01-01

    Test-based accountability as well as value-added asessments and much experimental and quasi-experimental research in education rely on achievement tests to measure student skills and knowledge. Yet, we know little regarding fundamental properties of these tests, an important example being the extent of measurement error and its implications for…

  16. Software product quality measurement

    OpenAIRE

    Godliauskas, Eimantas

    2016-01-01

    This paper analyses Ruby product quality measures, suggesting three new measures for Ruby product quality measurement tool Rubocop to measure Ruby product quality characteristics defined in ISO 2502n standard series. This paper consists of four main chapters. The first chapter gives a brief view of software product quality and software product quality measurement. The second chapter analyses object oriented quality measures. The third chapter gives a brief view of the most popular Ruby qualit...

  17. Revisiting diversity: cultural variation reveals the constructed nature of emotion perception.

    Science.gov (United States)

    Gendron, Maria

    2017-10-01

    The extent of cultural variation in emotion perception has long been assumed to be bounded by underlying universality. A growing body of research reveals, however, that evidence of universality in emotion perception is method-bound. Without the assumption of underlying universality, new lines of inquiry become relevant. Accumulating evidence suggests that cultures vary in what cues are relevant to perceptions of emotion. Further, cultural groups vary in their spontaneous inferences; mental state inference does not appear to be the only, or even most routine, mode of perception across cultures. Finally, setting universality assumptions aside requires innovation in the theory and measurement of culture. Recent studies reveal the promise of refinements in psychological approaches to culture. Together, the available evidence is consistent with a view of emotion perceptions as actively constructed by perceivers to fit the social and physical constraints of their cultural worlds. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. REVEAL II: Seasonality and spatial variability of particle and visibility conditions in the Fraser Valley

    DEFF Research Database (Denmark)

    Pryor, S.C.; Barthelmie, R.J.

    2000-01-01

    This paper presents data collected during a year-long field experiment (REVEAL II) in the Fraser Valley, British Columbia. The data are used to provide information regarding ambient visibility conditions and fine particle concentrations in the valley. Although average fine mass measured during...... REVEAL II was 8-9 mu g m(-3), the fine particle mass has high light-scattering efficiencies and the visual range is frequently below publicly defined acceptable levels. For example, data indicate that during the fall the visual range is frequently below 20 km even under favorable meteorological...... conditions. Source apportionment analyses of mass and particle light-scattering indicate motor vehicles may contribute as much as 40% of the fine particle mass in the central valley and up to one-third of the particle light-scattering. In addition to characterizing conditions in the Fraser Valley, slides...

  19. Validation of Sodar Measurements for Wind Power

    DEFF Research Database (Denmark)

    Hansen, Kurt Schaldemose

    2006-01-01

    A ground-based SODAR has been tested for 1½ years together with a traditional measurement set-up consisting of cups and vanes for measuring wind data for wind power assessment at a remote location. Many problems associated to the operation of a remote located SODAR have been solved during...... the project and a new remote power system has been designed. A direct comparison between SODAR and cup measurements revealed a limitation for the SODAR measurements during different weather conditions, especially since the SODAR was not able to measure wind speeds above 15 m/s due to an increasing back......-ground noise. Instead, using the SODAR as a profiler to establish representative wind speed profiles was successful. These wind speed profiles are combined with low height reference measurements to establish reliable hub height wind speed distributions. Representative wind speed profiles can be establish...

  20. Contact angle measurement of natural materials.

    Science.gov (United States)

    Zhao, Tianyi; Jiang, Lei

    2018-01-01

    Contact angle (CA) is the most important parameter used to quantify the wettability of solid surfaces. In order to evaluate wettability performance, numerous methods have been developed to measure the CA of solid surfaces. Recent years have seen increased focus on the special wettability performance of various biological materials. Biomimetic wettability has become one of the most popular research fields, and novel CA measurements have been invented accordingly. In this protocol, we introduce several CA measurement techniques mainly based on the image capture method, which is commonly to investigate the wettability of natural materials. According to the solid/liquid/gas context, we classify CA measurements into three types: in air, under liquid, and air bubble measurements, and describe methods for each. The precise measurement of CA together with study of surface structure can reveal the mechanisms of special wettability, thus accelerating the investigation of biomaterials. Copyright © 2017. Published by Elsevier B.V.

  1. Recommendations for practical measures to mitigate the impact of aquaculture on the environment in three areas of the Philippines

    Directory of Open Access Journals (Sweden)

    Tarzan Legović

    2008-12-01

    Full Text Available An assessment of the severity and extent of aquaculture impact and the estimation of sustainable carrying capacity were undertaken in three areas of the Philippines - Bolinao (marine site, Dagupan, (brackishwater and Taal Lake (freshwater. This paper describes the potential mitigating measures that could be taken to reduce nutrient release from aquaculture, increase nutrient uptake using extractive species, and possible early warning systems for critical states of the tide when there is reduced flushing.

  2. GAE detection for mass measurement for plasma density control. JET article 14 contract no 950104. Final report

    International Nuclear Information System (INIS)

    Lister, J.B.; Ridder, G. de; Villard, L.

    1997-01-01

    In view of the interest in obtaining a direct mass measurement in JET D-T plasmas, ultimately for D/T ratio control, the CRPP has performed numerical simulation work to verify the underlying method. The work undertaken is described and the conclusions are presented. The use of the GAE in JET is concluded to be less interesting than initially hoped. The reasons are discussed. Such a method, however, provide useful additional information. (author) figs., tabs., 5 refs

  3. Update of computer applications associated to measuring equipment of the services of internal dosimetry of NPPS and Tecnatom

    International Nuclear Information System (INIS)

    Bravo, B.; Sollet, E.; Serrano, E.

    2014-01-01

    Within the continuous improvement processes that take place in all the activities taking place in the Spanish nuclear power plants, and as a result of implementation of ISO Standards for Internal Dosimetry, has undertaken a review, improvement and updating INDAC ALEDIN and applications associated with measuring equipment and DIYs Quicky kind Personal Internal Dosimetry Services of the Spanish nuclear power plants and Tecnatom This paper presents updates capacities both tools. (Author)

  4. Theory of Effectiveness Measurement

    National Research Council Canada - National Science Library

    Bullock, Richard K

    2006-01-01

    .... Currently, however, there is no formal foundation for formulating effectiveness measures. This research presents a new framework for effectiveness measurement from both a theoretical and practical view...

  5. Semiconductor Electrical Measurements Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Semiconductor Electrical Measurements Laboratory is a research laboratory which complements the Optical Measurements Laboratory. The laboratory provides for Hall...

  6. A rare case of dermatomyositis revealed during pregnancy with ...

    African Journals Online (AJOL)

    There are only few case reports in the literature documenting outcome of pregnancy in patients with DM in contrast with those of other connective tissue diseases especially when dermatomyositis is revealed during pregnancy , most of the publications reported a poor prognosis for both the mother and the fetus , yet, in our ...

  7. Heat islands over Mumbai as revealed by autorecorded ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Earth System Science; Volume 125; Issue 1. Heat islands over Mumbai as revealed by autorecorded thermograph data. A K Srivastava James Voogt ... One data point (Coloba, Mumbai) is in centre of the city and the other one (Santacruz, Mumbai) is at the airport. The study finds that there were ...

  8. Extensive translational regulation during seed germination revealed by polysomal profiling

    NARCIS (Netherlands)

    Bai, Bing; Peviani, Alessia; Horst, van der Sjors; Gamm, Magdalena; Snel, Berend; Bentsink, Leónie; Hanson, Johannes

    2017-01-01

    This work investigates the extent of translational regulation during seed germination. The polysome occupancy of each gene is determined by genome-wide profiling of total mRNA and polysome-associated mRNA. This reveals extensive translational regulation during Arabidopsis thaliana seed

  9. Comparative mapping reveals similar linkage of functional genes to ...

    Indian Academy of Sciences (India)

    logous genes and QTL of yield-related traits by silico map- ping and population mapping in O. sativa. Our results revealed that B. napus and O. sativa shared homologous se- quences of genes with similar functions, as well as consistent linkage relationships between genes and agronomic traits. Materials and methods.

  10. [Elbow abscess revealing cat-scratch disease: about a case].

    Science.gov (United States)

    Nkaoui, Mustafa; El Bardouni, Ahmed; Lazrek, Omar; Ibo, Nasser; Zouaidia, Fouad; Kharmaz, Mohamed; Elouadghiri, Mohamed; Lamrani, Omar; Mahfoud, Mustapha; Berrada, Mohamed Saleh

    2017-01-01

    Cat-scratch disease (CSD) is a common cause of chronic benign lymphadenopathy in the child and the young adult. Bartonella henselae is the agent responsible for this disease. Common symptoms include regional lymphadenopathy associated with fever. We report a clinically atypical and potentially misleading case of a 18-year old girl with CSD revealed by elbow abscess.

  11. Revealing gene action for production characteristics by inbreeding ...

    African Journals Online (AJOL)

    Revealing gene action for production characteristics by inbreeding, based on a long-term selection ... The gene action involved in the expression of production characters was investigated, using the effect of the theoretical inbreeding ..... and predicted selection responses for growth, fat and lean traits in mice. J. Anim. Sci.

  12. Genetic and biochemical evidences reveal novel insights into the ...

    Indian Academy of Sciences (India)

    2016-10-26

    Oct 26, 2016 ... repair. Here, we reveal a crucial role for Sae2 in DNA replication stress. We show that different mutant alleles of SAE2 cause hypersensitivity to genotoxic agents, and when ... way, known as the DNA damage response is a collective cell ...... replication fork reversal catalyzed by Mycobacterium tubercu-.

  13. Thrombotic Microangiopathy Revealing Bone Metastases from an Ethmoid Sinus Carcinoma

    Directory of Open Access Journals (Sweden)

    Mony Chenda Morisse

    2016-08-01

    Full Text Available Cancer-related thrombotic microangiopathy (TMA is a rare entity whose clinical and biological characteristics have been described in various tumors. Here we describe the first case of cancer-related TMA revealing diffuse bone metastases from an ethmoid sinus carcinoma.

  14. Cotranslational protein folding reveals the selective use of ...

    Indian Academy of Sciences (India)

    3Department of Biotechnology and Dr. B. C. Guha Centre for Genetic Engineering and Biotechnology, Ballygunge Science. College, University of Calcutta, 35 Ballygunge Circular Road, Kolkata 700 019, India. [Ray S. K., Baruah V. J., Satapathy S. S. and Banerjee R. 2014 Cotranslational protein folding reveals the selective ...

  15. PCR-based identification reveals unique Southern African internal ...

    African Journals Online (AJOL)

    Previous studies on helminths of dogs have revealed a relatively high prevalence of Ancylostoma spp. in dogs in Southern Africa. Ancylostoma caninum, and to a lesser extent, A. braziliense have been reported as the predominant species in dogs based on either morphology of eggs or of adult parasites. The reliability of ...

  16. On galaxy spiral arms' nature as revealed by rotation frequencies

    NARCIS (Netherlands)

    Roca-Fabrega, Santi; Valenzuela, Octavio; Figueras, Francesca; Romero-Gomez, Merce; Velazquez, Hector; Antoja Castelltort, Teresa; Pichardo, Barbara

    2013-01-01

    High-resolution N-body simulations using different codes and initial condition techniques reveal two different behaviours for the rotation frequency of transient spiral arms like structures. Whereas unbarred discs present spiral arms nearly corotating with disc particles, strong barred models

  17. Genetic relationships revealed by simple sequence repeat (SSR ...

    African Journals Online (AJOL)

    Genetic relationships revealed by simple sequence repeat (SSR) markers among Ghanaian cassava cultivars released by different research groups. ... Genetic diversity was observed within populations (HS = 0.552) and, therefore, suggesting a low rate of inter-population gene flow among the individuals constituting the ...

  18. An acute adrenal insufficiency revealing pituitary metastases of lung ...

    African Journals Online (AJOL)

    An acute adrenal insufficiency revealing pituitary metastases of lung cancer in an elderly patient. ... The hypothalamic-pituitary MRI showed a pituitary hypertrophy, a nodular thickening of the pituitary stalk. The chest X Rays ... Hence we concluded to a lung cancer with multiple pituitary and adrenal gland metastases.

  19. Puzzles in modern biology. I. Male sterility, failure reveals design.

    Science.gov (United States)

    Frank, Steven A

    2016-01-01

    Many human males produce dysfunctional sperm. Various plants frequently abort pollen. Hybrid matings often produce sterile males. Widespread male sterility is puzzling. Natural selection prunes reproductive failure. Puzzling failure implies something that we do not understand about how organisms are designed. Solving the puzzle reveals the hidden processes of design.

  20. Genetic and biochemical evidences reveal novel insights into the ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 41; Issue 4. Genetic and biochemical evidences reveal novel insights into the mechanism underlying Saccharomyces cerevisiae Sae2-mediated abrogation of DNA replication stress. INDRAJEET GHODKE K MUNIYAPPA. ARTICLE Volume 41 Issue 4 December 2016 pp ...

  1. Whole exome sequencing reveals a MLL de novo mutation ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics; Volume 94; Issue 4. Whole exome sequencing reveals a de novo mutation associated with mild developmental delay ... Keywords. Wiedemann–Steiner syndrome; whole exome sequencing; hairy elbows; hypertrichosis cubiti; gene; KMT2A; developmental delay; children.

  2. Nilaja Sun's "No Child"...: Revealing Teaching and Learning through Theater

    Science.gov (United States)

    Hetland, Lois

    2009-01-01

    This article presents an analysis of Nilaja Sun's one-woman play, "No Child" . . ., that applies the Studio Habits of Mind framework to reveal essential features of great teaching artistry and great teaching. The play conveys much about twenty-first century schools and the policies that control them; about respect, equity, justice, and the lack of…

  3. Molecular variation in Cucumis melo as revealed by isoenzyme and ...

    African Journals Online (AJOL)

    Molecular variation in Cucumis melo as revealed by isoenzyme and RAPD markers. Tarek M Mohamed. Abstract. No Abstract. The Egyptian Journal of Biochemistry and Molecular Biology Vol. 23(2) 2005: 141-153. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT.

  4. Cotranslational protein folding reveals the selective use of ...

    Indian Academy of Sciences (India)

    [Ray S. K., Baruah V. J., Satapathy S. S. and Banerjee R. 2014 Cotranslational protein folding reveals the selective use of synonymous codons along the coding sequence of a low expression gene. J. Genet. 93, 613–617]. Due to the degeneracy in the genetic code, many amino acids are encoded by more than one codon, ...

  5. Comparative analyses of genetic risk prediction methods reveal ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics; Volume 94; Issue 1. Comparative analyses of genetic risk prediction methods reveal extreme diversity of genetic predisposition to nonalcoholic fatty liver disease (NAFLD) among ethnic populations of India. Ankita Chatterjee Analabha Basu Abhijit Chowdhury Kausik Das Neeta ...

  6. Reliability of Different Facial Measurements for Determination of Vertical Dimension of Occlusion in Edentulous Using Accepted Facial Dimensions Recorded from Dentulous Subjects

    OpenAIRE

    Nagpal, Abhishek; Parkash, Hari; Bhargava, Akshay; Chittaranjan, B.

    2013-01-01

    The study was undertaken to evaluate the reliability of different facial measurements for determination of vertical dimension of occlusion in edentulous subjects using accepted facial dimensions recorded from dentulous subjects. The hypothesis was that facial measurements can be used to obtain the vertical dimension of occlusion for edentulous patients where no pre-extraction records exist. A total of 180 subjects were selected in the age groups of 50–60 years, consisting of 75 dentate male a...

  7. Measurements and calculations of nuclear deformations

    International Nuclear Information System (INIS)

    Quentin, P.

    1975-01-01

    Main sources of experimental data pertaining to equilibrium deformation properties are shortly reviewed. Different approximations and methods relevant to their systematical calculations are discussed and compared. Finally, a rapid survey of some open problems is undertaken [fr

  8. Quantum behaviour of measuring apparatus

    International Nuclear Information System (INIS)

    Amri, T.

    2011-05-01

    This thesis explores the quantum behavior of measurement apparatus with illustrations in quantum optics. This is the first study of quantum properties of measurements performed by any kind of devices. We show that the quantum properties of a measurement, such as its projective or non-classical character, are revealed only by the quantum states of an unusual approach of quantum physics: the retrodictive approach. This approach involves retro-predictions about state preparations leading to a given measurement result, contrary to the predictive approach with which we usually make predictions about the results of an experiment. By clarifying the mathematical foundations of the retrodictive approach, we propose a general procedure for reconstructing the quantum states of this approach: the retrodicted states. We have realized these reconstructions for single-photon detectors, widely used in quantum cryptography for instance. This is the first tomography of quantum states totally based on the retrodictive approach and preparation choices, contrary to usual reconstructions based on measurement results. These tomographies enabled us to study experimentally the noise influence on the quantum properties of measurements performed by these detectors, in particular their transition from a strongly quantum behavior into a more classical behavior. Finally, we propose a detector of Schroedinger's Cat states of light, which are superpositions of incompatible quasi-classical states of light. In a modern version of a thought experiment proposed by Eugene Wigner in 1961, such a device could allow the Wigner's Friend to detect a Schroedinger's Cat, contrary to human eyes for which we specify some quantum properties. We generalize the use of such a non-classical detector to an estimation protocol, totally based on the retrodictive approach and preparation choices. Such a procedure could enable optimal estimations, by reaching the quantum Cramer-Rao bound, which is a very topical issue

  9. Sexual size dimorphism and sex determination by morphometric measurements in locally adapted muscovy duck (Cairina moschata in Nigeria

    Directory of Open Access Journals (Sweden)

    Abel Olusegun OGUNTUNJI

    2015-11-01

    Full Text Available Sexual size dimorphism (SSD is a common phenomenon in most mammalian and poultry species. This study was undertaken to investigate SSD in nondescript locally adapted Muscovy ducks in Nigeria by applying descriptive analysis, sexual dimorphism index (SDI, sexual size dimorphism index (SSDI and Principal Component analysis to morphological variables. Besides, attempt was made to identify best morphological predictors of sex using Stepwise Discriminant analysis. Data on ten morphological traits; body weight, body girth, body length, wing length, shank length, shank circumference, thigh length, total leg length, bill length and bill width were taken from 1,020 extensively managed adult Muscovy ducks comprising 287 males and 733 females. These birds were randomly sampled from Rain Forest, Derived Savanna and Guinea Savanna agro-ecological zones of Nigeria. Sex significantly (P < 0.001 affected all morphometric measurements in favour of males. Assessment of relative contribution of morphological traits to SSD through SDI and SSDI revealed that body weight followed by skeletal frame-related variables (body length and wing length were the most dimorphic traits. Three Principal Components were generated for each sex; accounting for 62.70 % and 54.24 % of the total variance explained of male and female ducks, respectively. In tandem with the SDI and SSDI results, Stepwise Discriminant analysis indicated body weight as the best predictor of sex of adult Muscovy ducks followed by wing length and body length; correctly classifying 98.5 % of ducks and are reliable for sex determination in the field. The established SSD in this study could be employed for description, utilization, selection and planning of improvement programs of male and female Muscovy ducks.

  10. Measuring Interfacial Polymerization Kinetics Using Microfluidic Interferometry.

    Science.gov (United States)

    Nowbahar, Arash; Mansard, Vincent; Mecca, Jodi M; Paul, Mou; Arrowood, Tina; Squires, Todd M

    2018-03-07

    A range of academic and industrial fields exploit interfacial polymerization in producing fibers, capsules, and films. Although widely used, measurements of reaction kinetics remain challenging and rarely reported, due to film thinness and reaction rapidity. Here, polyamide film formation is studied using microfluidic interferometry, measuring monomer concentration profiles near the interface during the reaction. Our results reveal that the reaction is initially controlled by a reaction-diffusion boundary layer within the organic phase, which allows the first measurements of the rate constant for this system.

  11. Complex regulation of mucosal pentraxin (Mptx) revealed by discrete micro-anatomical locations in colon

    NARCIS (Netherlands)

    Drew, J.E.; Farquharson, A.J.; Keijer, J.; Barrera, L.N.

    2006-01-01

    Recently a mucosal pentraxin, Mptx, regulated by heme and calcium was reported in rat gut mucosal scrapings using microarray strategies. Considering the heterogeneity of gut mucosa scrapings and the widespread use of the rat as a model to study colon pathologies this study was undertaken to generate

  12. Mutational scanning of the human serotonin transporter reveals fast translocating serotonin transporter mutants

    DEFF Research Database (Denmark)

    Kristensen, Anders S; Larsen, Mads B; Johnsen, Laust B

    2004-01-01

    and anxiety. In the present study we have undertaken a mutational scanning of human SERT in order to identify residues that are responsible for individual differences among related monoamine transporters. One mutant, G100A, was inactive in transport. However, ligand binding affinity was similar to wild...

  13. Reading on Paper and Digitally: What the Past Decades of Empirical Research Reveal

    Science.gov (United States)

    Singer, Lauren M.; Alexander, Patricia A.

    2017-01-01

    This systematic literature review was undertaken primarily to examine the role that print and digitally mediums play in text comprehension. Overall, results suggest that medium plays an influential role under certain text or task conditions or for certain readers. Additional goals were to identify how researchers defined and measured…

  14. A Pattern of Perseveration in Cocaine Addiction May Reveal Neurocognitive Processes Implicit in the Wisconsin Card Sorting Test

    Science.gov (United States)

    Woicik, Patricia A.; Urban, Catherine; Alia-Klein, Nelly; Henry, Ashley; Maloney, Thomas; Telang, Frank; Wang, Gene-Jack; Volkow, Nora D.; Goldstein, Rita Z.

    2011-01-01

    The ability to adapt behavior in a changing environment is necessary for humans to achieve their goals and can be measured in the lab with tests of rule-based switching. Disease models, such as cocaine addiction, have revealed that alterations in dopamine interfere with adaptive set switching, culminating in perseveration. We explore perseverative…

  15. Cost benefit analysis of policy measures in the transport sector

    Energy Technology Data Exchange (ETDEWEB)

    Buus Kristensen, N. [COWI (Denmark)

    1996-12-01

    The Government has introduced a national target for the reduction of CO{sub 2} emissions from the transport sector, which aims to stabilize emissions at the 1988 level, by the year 2005. This target was first formalized in the Government`s 1990 transport action plan, and later repeated in `Traffic 2005`, published in December 1993. The latter document also makes reference to six strategies, which the Government proposed in order to attain the national target. The majority of the transport policy measures will impact on CO{sub 2} emissions from the sector, even if they are targeted at different objectives, e.g. road safety, air pollution, time savings, etc. A long-list of potential measures, which might be adopted with the primary purpose is to reduce CO{sub 2} emissions, has been identified from the six overall strategies. The measures identified have been subjected to detailed analyses, to ascertain all the potential impacts. The main emphasis has been on clarifying the potential efficacy of each of the measures in reducing CO{sub 2} emissions, and the social costs in a wide sense. The analysis assumes that each policy measure is implemented separately. A methodology is developed that presents the respective consequences in commensurate terms. Similar calculations are undertaken for two different combinations of policy measures. (EG)

  16. Radon flux measurement methodologies

    International Nuclear Information System (INIS)

    Nielson, K.K.; Rogers, V.C.

    1984-01-01

    Five methods for measuring radon fluxes are evaluated: the accumulator can, a small charcoal sampler, a large-area charcoal sampler, the ''Big Louie'' charcoal sampler, and the charcoal tent sampler. An experimental comparison of the five flux measurement techniques was also conducted. Excellent agreement was obtained between the measured radon fluxes and fluxes predicted from radium and emanation measurements

  17. Completely random signed measures

    DEFF Research Database (Denmark)

    Hellmund, Gunnar

    Completely random signed measures are defined, characterized and related to Lévy random measures and Lévy bases.......Completely random signed measures are defined, characterized and related to Lévy random measures and Lévy bases....

  18. αs Measurements

    Indian Academy of Sciences (India)

    Abstract. The strong coupling constant, s, has been determined from many pure inclusive and semi-inclusive measurements. All these measurements, measured at different scales, are consistent among each other and the measurements can be combined to give s()=0.118 ± 0.003.

  19. Power Curve Measurements REWS

    DEFF Research Database (Denmark)

    Federici, Paolo; Georgieva Yankova, Ginka

    The report describes power curve measurements carried out on a given wind turbine. The measurements are carried out in accordance to a draft of IEC 61400-12-1 Ed.2.......The report describes power curve measurements carried out on a given wind turbine. The measurements are carried out in accordance to a draft of IEC 61400-12-1 Ed.2....

  20. Inspector measurement verification activities

    International Nuclear Information System (INIS)

    George, R.S.; Crouch, R.

    e most difficult and complex activity facing a safeguards inspector involves the verification of measurements and the performance of the measurement system. Remeasurement is the key to measurement verification activities. Remeasurerements using the facility's measurement system provide the bulk of the data needed for determining the performance of the measurement system. Remeasurements by reference laboratories are also important for evaluation of the measurement system and determination of systematic errors. The use of these measurement verification activities in conjunction with accepted inventory verification practices provides a better basis for accepting or rejecting an inventory. (U.S.)

  1. Radioactive measurements in industry

    International Nuclear Information System (INIS)

    Rozsa, S.

    1979-01-01

    The book reviews the industrial applications of radioactive isotopes. The introduction refreshes the reader's knowledge of radioactive decay, radioactive radiations and measuring techniques. Then the special problems of threshold detection, level indication, thickness measurements, measurements of layer thickness applying beta-reflexion, density measurements, humidity measurements, and the determination of the composition of different materials are detailed. In each chapter the principle of a given technique, the available equipment, the possibilities of controlling systems and results of concrete measurements are discussed. The last chapter deals with the practical aspects of the industrial installation of radioactive measuring systems. (L.E.)

  2. Measuring agricultural policy bias

    DEFF Research Database (Denmark)

    Jensen, Henning Tarp; Robinson, Sherman; Tarp, Finn

    2010-01-01

    Measurement is a key issue in the literature on price incentive bias induced by trade policy. We introduce a general equilibrium measure of the relative effective rate of protection, which generalizes earlier protection measures. For our fifteen sample countries, results indicate that the agricul......Measurement is a key issue in the literature on price incentive bias induced by trade policy. We introduce a general equilibrium measure of the relative effective rate of protection, which generalizes earlier protection measures. For our fifteen sample countries, results indicate...... protection measure is therefore uniquely suited to capture the full impact of trade policies on relative agricultural price incentives....

  3. Measurement of communication

    International Nuclear Information System (INIS)

    1998-08-01

    This book is one of series of information communication, which deals with measurement of communication. It is divided into six chapters. The contents are foundation of measurement with classification and principle, Basic measurement on current, voltage, electric resistance, power and impedance, measurement of communication line with way by L3 tester, BW tester and pulse tester, measurement of optical fiber cable of equipment and method, Test and measurement of information communication equipment about test of modulator and use, measurement of cable broadcasting equipment on transmission level and main transmission equipment.

  4. Dynamic single-cell NAD(P)H measurement reveals oscillatory metabolism throughout the E. coli cell division cycle

    NARCIS (Netherlands)

    Zhang, Zheng; Milias-Argeitis, Andreas; Heinemann, Matthias

    2018-01-01

    Recent work has shown that metabolism between individual bacterial cells in an otherwise isogenetic population can be different. To investigate such heterogeneity, experimental methods to zoom into the metabolism of individual cells are required. To this end, the autofluoresence of the redox

  5. Micrometeorological measurements over 3 years reveal differences in N2 O emissions between annual and perennial crops.

    Science.gov (United States)

    Abalos, Diego; Brown, Shannon E; Vanderzaag, Andrew C; Gordon, Robert J; Dunfield, Kari E; Wagner-Riddle, Claudia

    2016-03-01

    Perennial crops can deliver a wide range of ecosystem services compared to annual crops. Some of these benefits are achieved by lengthening the growing season, which increases the period of crop water and nutrient uptake, pointing to a potential role for perennial systems to mitigate soil nitrous oxide (N2 O) emissions. Employing a micrometeorological method, we tested this hypothesis in a 3-year field experiment with a perennial grass-legume mixture and an annual corn monoculture. Given that N2 O emissions are strongly dependent on the method of fertilizer application, two manure application options commonly used by farmers for each crop were studied: injection vs. broadcast application for the perennial; fall vs. spring application for the annual. Across the 3 years, lower N2 O emissions (P crop, even though annual N2 O emissions increased tenfold for the perennial after ploughing. The percentage of N2 O lost per unit of fertilizer applied was 3.7, 3.1 and 1.3 times higher for the annual for each consecutive year. Differences in soil organic matter due to the contrasting root systems of these crops are probably a major factor behind the N2 O reduction. We found that a specific manure management practice can lead to increases or reductions in annual N2 O emissions depending on environmental variables. The number of freeze-thaw cycles during winter and the amount of rainfall after fertilization in spring were key factors. Therefore, general manure management recommendations should be avoided because interannual weather variability has the potential to determine if a specific practice is beneficial or detrimental. The lower N2 O emissions of perennial crops deserve further research attention and must be considered in future land-use decisions. Increasing the proportion of perennial crops in agricultural landscapes may provide an overlooked opportunity to regulate N2 O emissions. © 2015 John Wiley & Sons Ltd.

  6. The New Juan Crow in Education: Revealing Panoptic Measures and Inequitable Resources That Hinder Latina/o Postsecondary Pathways

    Science.gov (United States)

    Madrigal-Garcia, Yanira I.; Acevedo-Gil, Nancy

    2016-01-01

    This qualitative study examined the distribution of inequitable resources, a culture of control, and implications for postsecondary pathways for Latinas/os in five California high schools. This study integrated critical race theory in education, school culture, and the concept of "panopticon" to examine school structures, climate, and…

  7. Simultaneous single-molecule measurements of phage T7 replisome composition and function reveal the mechanism of polymerase exchange

    NARCIS (Netherlands)

    Loparo, Joseph J.; Kulczyk, Arkadiusz W.; Richardson, Charles C.; Oijen, Antoine M. van

    2011-01-01

    A complete understanding of the molecular mechanisms underlying the functioning of large, multiprotein complexes requires experimental tools capable of simultaneously visualizing molecular architecture and enzymatic activity in real time. We developed a novel single-molecule assay that combines the

  8. Salinity measurements collected by fishermen reveal a ``River in the Sea`` flowing along the eastern coast of India

    Digital Repository Service at National Institute of Oceanography (India)

    Chaitanya, A.V.S.; Lengaigne, M.; Vialard, J.; Gopalakrishna, V.V.; Durand, F.; KranthiKumar, C.; Amritash, S.; Suneel, V.; Papa, F.; Ravichandran, M.

    Being the only tropical ocean bounded by a continent to the north, the Indian Ocean is home to the most powerful monsoon system on Earth. Monsoonal rains and winds induce huge river discharges and strong coastal currents in the northern Bay...

  9. Potential language and attentional networks revealed through factor analysis of rCBF data measured with SPECT

    DEFF Research Database (Denmark)

    McLaughlin, T; Steinberg, B; Christensen, B

    1992-01-01

    We used changes in regional cerebral blood flow (rCBF) to disclose regions involved in central auditory and language processing in the normal brain. rCBF was quantified with a fast-rotating, single-photon emission computerized tomograph (SPECT) and inhalation of 133Xe. rCBF data were obtained sim...... brain networks involved in (I) auditory/linguistic, (II) attentional, and (III) visual imaging activity.......We used changes in regional cerebral blood flow (rCBF) to disclose regions involved in central auditory and language processing in the normal brain. rCBF was quantified with a fast-rotating, single-photon emission computerized tomograph (SPECT) and inhalation of 133Xe. rCBF data were obtained...... simultaneously from parallel, transverse slices of the brain. The lower slice was positioned to include both Broca's and Wernicke's areas. The upper slice included regions generally regarded by neurobehaviorists as less related to primary auditory or linguistic functions. We presented three types of auditory...

  10. Motor coordination and balance measurements reveal differential pathogenicity of currently spreading enterovirus 71 strains in human SCARB2 transgenic mice.

    Science.gov (United States)

    Chen, Mei-Feng; Shih, Shin-Ru

    2016-12-01

    Enterovirus 71 (EV71) has caused large-scale epidemics with neurological complications in the Asia-Pacific region. The C4a and B5 strains are the two major genotypes circulating in many countries recently. This study used a new protocol, a motor coordination task, to assess the differential pathogenicity of C4a and B5 strains in human SCARB2 transgenic mice. We found that the pathogenicity of C4a viruses was more severe than that of B5 viruses. Moreover, we discovered that an increased level of monocyte chemoattractant protein-1 was positively correlated with severely deficient motor function. This study provides a new method for evaluating EV71 infection in mice and distinguishing the severity of the symptoms caused by different clinical strains, which would contribute to studies of pathogenesis and development of vaccines and antivirals in EV71 infections.

  11. Equipment for temperature measurements

    OpenAIRE

    HORELICA, Josef

    2008-01-01

    This work deals with theoretical description, practical connection of temperature measuring instruments and how they function while measuring the temperature. This document explaines basic concepts of temperature, temperature scales and temperature measuring. Further there are introduced standard types of sensors used in these measuring intruments. This document includes a picture presentation in PowerPoint, where an aggregate table of sensors and an application of these sensors in measuring ...

  12. Deep brain stimulation reveals emotional impact processing in ventromedial prefrontal cortex

    DEFF Research Database (Denmark)

    Gjedde, Albert; Geday, Jacob

    2009-01-01

    -noradrenaline reuptake sites. We tested the hypothesis in patients with Parkinson's disease in whom we had measured the changes of blood flow everywhere in the brain associated with the deep brain stimulation of the subthalamic nucleus. We determined the emotional reactivity of the patients as the average impact......We tested the hypothesis that modulation of monoaminergic tone with deep-brain stimulation (DBS) of subthalamic nucleus would reveal a site of reactivity in the ventromedial prefrontal cortex that we previously identified by modulating serotonergic and noradrenergic mechanisms by blocking serotonin...

  13. Parainfluenza virus type 5 (PIV-5) morphology revealed by cryo-electron microscopy.

    Science.gov (United States)

    Terrier, Olivier; Rolland, Jean-Paul; Rosa-Calatrava, Manuel; Lina, Bruno; Thomas, Daniel; Moules, Vincent

    2009-06-01

    The knowledge of parainfluenza type 5 (PIV-5) virion morphology is essentially based on the observation of negatively stained preparations in conventional transmission electron microscopy (CTEM). In this study, the ultrastructure of frozen-hydrated intact PIV-5 was examined by cryo-electron microscopy (cryo-EM). Cryo-EM revealed a majority of spherical virions (70%), with a lower pleiomorphy than originally observed in CTEM. Phospholipid bilayer thickness, spike length and glycoprotein spikes density were measured. About 2000 glycoprotein spikes were present in an average-sized spherical virion. Altogether, these data depict a more precise view of PIV-5 morphology.

  14. Geophysical Measurements at Merseburg Cathedral

    Science.gov (United States)

    Meier, Thomas; Erkul, Ercan; Schulte-Kortnack, Detlef; Sobott, Robert; Hilbert, Helene; Esel, Yunus; Tesch, Marcel; Wiemann, Timo

    2017-04-01

    Merseburg Cathedral has been founded in 1015 by Bishop Thietmar von Merseburg and has been converted into a gothic cathedral from 1510 to 1517 by Bishop Thilo von Trotha. The cathedral together with the cloister, the castle and several appurtenant buildings are well preserved. The entire complex represents one of the most complete examples of medieval royal palaces and bishop's sees in Germany northeast of the Roman Limes. Here we present examples of geophysical measurements at the cathedral namely ultrasonic surface measurements, ground penetrating radar (GPR) as well as thermographic measurements. Ultrasonic surface measurements have been carried out at epitaphs made of sandstone to quantify changes in stone properties due to weathering. The 95 measurements reveal a strong variability in Rayleigh wave velocities ranging from about 800 m/s to 2000 m/s. Unweathered parts of the sandstone epitaphs show Rayleigh wave velocities of about 1500 m/s. A reduction in Rayleigh wave velocities hints at loosening of the rock surface whereas an increase is due to surficial black crusts with pores filled mainly by gypsum. Waveform inversion of the dispersed Rayleigh waveform yields depth profiles of the shear-wave velocity indicating the thickness of altered surficial layers. Also a loosening below the black crust may be detected non-destructively. A number of measurements have been repeated after one year and after a rainy day. Statistical analysis shows that random errors in Rayleigh wave velocities are less than about 3 %. Increase of moisture in porous sandstones leads to stronger damping of the Rayleigh wave and consequently to a reduction in Rayleigh wave velocities by up to about 10 %. At strongly altered epitaphs a reduction in Rayleigh wave velocity by up to 20 % has been observed within one year. Within one day an increase of up to about 7 % may indicate stiffening of black crusts due to moisture absorption. GPR measurements have been performed at several locations

  15. Identifying an outcome measure to assess the impact of Mobility Dogs.

    Science.gov (United States)

    Mudge, Suzie; Rewi, Dallas; Channon, Alexis

    2017-01-01

    Mobility Dogs® trains dogs to work with people with physical disabilities to increase independence, confidence, self-esteem and participation. Mobility Dogs® seeks to critically evaluate and improve its services as it grows. This study aimed to identify and implement a standardised outcome measure into practice at Mobility Dogs®. Based on the Consolidated Framework for Implementation Research and guided by a steering group of key stakeholders, a three-phase approach was developed to identify and assess an outcome measure. The steering group highlighted the organisation's specific needs, selected participation as the assessment domain and identified core utility requirements of the measure. A comprehensive review of evidence was undertaken to identify and rank potential measures according to the specified needs. Of the seven participation outcome measures that met inclusion criteria, the three highest ranked measures were critically evaluated by the steering group to determine suitability against the organisation's needs. The Impact on Participation and Autonomy (IPA) was selected for implementation into practice at Mobility Dogs®. Use of the IPA is an important first step for Mobility Dogs® to test the benefits of trained service dogs. This process could be replicated by other service dog organisations to identify outcome measures to assess their own services. Implications for Rehabilitation Service dogs (such as Mobility Dogs® in New Zealand) assist people living with physical impairments by performing tasks, however there is limited evidence on outcomes. The process for selecting an appropriate outcome measure for Mobility Dogs® involving partnership between Mobility Dogs® personnel and academics was an effective way to steer the project by determining important properties of the measure, before a search of the literature was undertaken. While the IPA was selected as the most appropriate outcome measure for use at Mobility Dogs®, it was the process that

  16. Microbiota analysis to reveal temperature abuse of fresh pork

    DEFF Research Database (Denmark)

    Buschhardt, Tasja; Bahl, Martin Iain; Hansen, Tina Beck

    monitored during aerobic chill-storage (4 °C and 7 °C) and temperature abuse (12 °C and 16 °C) for 96 hours, by culture-based methods and 16S rRNA gene sequencing. Bacterial genera that dominated during prolonged temperature abuse were Acinetobacter, Serratia and Pseudomonas, whereas chill-stored meat...... was dominated by Pseudomonas only. We also showed that the initial community affects subsequent changes during storage. The results suggest that principal coordinate analysis of beta diversity could be a useful tool to reveal temperature abused meat. Sequence data and culturing data revealed a strong positive......Violations of temperature regulations in the meat chain may affect meat safety. Methods are lacking to estimate whether meat has been subjected to temperature abuse. Exposure to too high temperatures may lead to systematic changes in the diverse bacterial communities of fresh meat. We investigated...

  17. Seasonal succession in zooplankton feeding traits reveals trophic trait coupling

    DEFF Research Database (Denmark)

    Kenitz, Kasia; Visser, Andre; Mariani, Patrizio

    2017-01-01

    The seasonal forcing of pelagic communities invokes a succession of the dominant phytoplankton and zooplankton species. Here, we characterize the seasonal succession of the plankton traits and their interactions using observations and model simulations of the plankton community in the western...... acquisition and photosynthesis, it also depends on grazing which couples feeding and motility traits across trophic guilds. Despite interannual variations in the species dominating the protist plankton community, the seasonal trait distribution reveals robust and repeatable seasonal patterns, changing between...... non-motile cells flourishing in spring and motile community dominating during summer. The zooplankton community is dominated by active feeding-current feeders with peak biomass in the late spring declining during summer. The model reveals how zooplankton grazing reinforces protist plankton seasonal...

  18. Microbiota analysis to reveal temperature abuse of fresh pork

    DEFF Research Database (Denmark)

    Buschhardt, Tasja; Bahl, Martin Iain; Hansen, Tina Beck

    2017-01-01

    Violations of temperature regulations in the meat chain may affect meat safety. Methods are lacking to estimate whether meat has been subjected to temperature abuse. Exposure to too high temperatures may lead to systematic changes in the diverse bacterial communities of fresh meat. We investigated...... monitored during aerobic chill-storage (4 °C and 7 °C) and temperature abuse (12 °C and 16 °C) for 96 hours, by culture-based methods and 16S rRNA gene sequencing. Bacterial genera that dominated during prolonged temperature abuse were Acinetobacter, Serratia and Pseudomonas, whereas chill-stored meat...... was dominated by Pseudomonas only. We also showed that the initial community affects subsequent changes during storage. The results suggest that principal coordinate analysis of beta diversity could be a useful tool to reveal temperature abused meat. Sequence data and culturing data revealed a strong positive...

  19. Running over rough terrain reveals limb control for intrinsic stability

    OpenAIRE

    Daley, Monica A.; Biewener, Andrew A.

    2006-01-01

    Legged animals routinely negotiate rough, unpredictable terrain with agility and stability that outmatches any human-built machine. Yet, we know surprisingly little about how animals accomplish this. Current knowledge is largely limited to studies of steady movement. These studies have revealed fundamental mechanisms used by terrestrial animals for steady locomotion. However, it is unclear whether these models provide an appropriate framework for the neuromuscular and mechanical strategies us...

  20. 'Big bang' of B-cell development revealed.

    Science.gov (United States)

    Murre, Cornelis

    2018-01-15

    Earlier studies have identified transcription factors that specify B-cell fate, but the underlying mechanisms remain to be revealed. Two new studies by Miyai and colleagues (pp. 112-126) and Li and colleagues (pp. 96-111) in this issue of Genes & Development provide new and unprecedented insights into the genetic and epigenetic mechanisms that establish B-cell identity. © 2018 Murre; Published by Cold Spring Harbor Laboratory Press.

  1. Genomic Perturbations Reveal Distinct Regulatory Networks in Intrahepatic Cholangiocarcinoma

    DEFF Research Database (Denmark)

    Nepal, Chirag; O'Rourke, Colm J; Oliveira, Douglas Vnp

    2018-01-01

    -mutation profiles and enriched pathways. High-throughput drug repositioning in seven patient-matched cell lines, chosen to reflect the genetic alterations specific for each patient group, confirmed in silico predictions of subgroup-specific vulnerabilities linked to enriched pathways. Intriguingly, patients lacking...... genes (IDH, KRAS, TP53) revealed unique oncogenic programs (mutational, structural, epi-mutational) that influence pharmacologic response in drug repositioning protocols. This genome dissection approach highlights the potential of individual mutations to induce extensive molecular heterogeneity...

  2. Spontaneous chylothorax revealing a mediastinal and abdominal lymph node tuberculosis.

    Science.gov (United States)

    Amar, Jihen Ben; Zaibi, Haifa; Dahri, Besma; Aouina, Hichem

    2017-04-01

    Chylothorax is a rare manifestation of tuberculosis. We report a case of spontaneous chylothorax due to tuberculosis. A 62-year-old woman was admitted with fever, chest pain and dyspnea. Chest and abdominal computed tomography revealed a fluid collection with necrotic mediastinal and abdominal lymph nodes. Biopsy of lymph nodes by mediastinoscopy. The patient was treated with anti-tuberculosis medication. He is clinically improved and his pleural effusion also completely resolved. Copyright © 2016. Published by Elsevier B.V.

  3. [Chicken pox recurrence revealing a renal adenocarcinoma in an adult].

    Science.gov (United States)

    Thieulent, N; Grezard, P; Wolf, F; Barrut, D; Perrot, H

    2000-09-01

    A new episode of chicken pox in adults who had a well documented infection previously is usually observed in immunocompromised individuals. The principal immunodeficiency factors are hematology diseases, acquired immunodeficiency disease and old age. We report here the case of a young woman who after a contaminating contact presented a recurrence of typical chicken pox. Morphological investigations evidenced a right kidney tumor which pathology revealed to be a renal adenocarcinoma. We discuss this pathological association and review cases reported in the literature.

  4. Digital tissue and what it may reveal about the brain.

    Science.gov (United States)

    Morgan, Josh L; Lichtman, Jeff W

    2017-10-30

    Imaging as a means of scientific data storage has evolved rapidly over the past century from hand drawings, to photography, to digital images. Only recently can sufficiently large datasets be acquired, stored, and processed such that tissue digitization can actually reveal more than direct observation of tissue. One field where this transformation is occurring is connectomics: the mapping of neural connections in large volumes of digitized brain tissue.

  5. Parascapular mass revealing primary tuberculosis of the posterior arch

    Science.gov (United States)

    Arbault, Anais; Ornetti, Paul; Chevallier, Olivier; Avril, Julien; Pottecher, Pierre

    2016-01-01

    We report the case of a parascapular abscess revealing primary tuberculosis of the posterior arch in a 31-year-old man. Sectional imaging is essential in order to detect the different lesions of this atypical spinal tuberculosis as osteolysis of the posterior arch extendible to vertebral body, osteocondensation, epidural extension which is common in this location, and high specificity of a zygapophysial, costo-vertebral or transverse arthritis. PMID:27709081

  6. [Commissioning of the newly constructed Beijing electron-positron collider BEPC, Beijing, China, and visit to SRRC to discuss magnet manufacturing and measurement methods, Taipei, Taiwan, November 11--27, 1988]: Foreign trip report

    International Nuclear Information System (INIS)

    Weng, W.T.

    1988-01-01

    The traveller was invited to IHEP to participate in the commissioning of the newly constructed Beijing electron-positron collider BEPC, give a status report on the AGS Booster Project and to assess the feasibility of sub-contracting booster sextupoles to IHEP. The trip to SRRC was undertaken to discuss magnet manufacturing and measurement methods

  7. Transient light-induced intracellular oxidation revealed by redox biosensor

    International Nuclear Information System (INIS)

    Kolossov, Vladimir L.; Beaudoin, Jessica N.; Hanafin, William P.; DiLiberto, Stephen J.; Kenis, Paul J.A.; Rex Gaskins, H.

    2013-01-01

    Highlights: •Time-resolved live cell imaging revealed light-induced oxidation. •Only the roGFP probe fused with glutaredoxin reveals photooxidation. •The transient oxidation is rapidly reduced by the cytosolic antioxidant system. •Intracellular photooxidation is media-dependent. •Oxidation is triggered exclusively by exposure to short wavelength excitation. -- Abstract: We have implemented a ratiometric, genetically encoded redox-sensitive green fluorescent protein fused to human glutaredoxin (Grx1-roGFP2) to monitor real time intracellular glutathione redox potentials of mammalian cells. This probe enabled detection of media-dependent oxidation of the cytosol triggered by short wavelength excitation. The transient nature of light-induced oxidation was revealed by time-lapse live cell imaging when time intervals of less than 30 s were implemented. In contrast, transient ROS generation was not observed with the parental roGFP2 probe without Grx1, which exhibits slower thiol-disulfide exchange. These data demonstrate that the enhanced sensitivity of the Grx1-roGFP2 fusion protein enables the detection of short-lived ROS in living cells. The superior sensitivity of Grx1-roGFP2, however, also enhances responsiveness to environmental cues introducing a greater likelihood of false positive results during image acquisition

  8. Transient light-induced intracellular oxidation revealed by redox biosensor

    Energy Technology Data Exchange (ETDEWEB)

    Kolossov, Vladimir L., E-mail: viadimer@illinois.edu [Institute for Genomic Biology, University of Illinois at Urbana-Champaign, 1206 W. Gregory Drive, Urbana, IL 61801 (United States); Beaudoin, Jessica N. [Institute for Genomic Biology, University of Illinois at Urbana-Champaign, 1206 W. Gregory Drive, Urbana, IL 61801 (United States); Department of Animal Sciences, University of Illinois at Urbana-Champaign, 1207 W. Gregory Drive, Urbana, IL 61801 (United States); Hanafin, William P. [Institute for Genomic Biology, University of Illinois at Urbana-Champaign, 1206 W. Gregory Drive, Urbana, IL 61801 (United States); DiLiberto, Stephen J. [Institute for Genomic Biology, University of Illinois at Urbana-Champaign, 1206 W. Gregory Drive, Urbana, IL 61801 (United States); Department of Animal Sciences, University of Illinois at Urbana-Champaign, 1207 W. Gregory Drive, Urbana, IL 61801 (United States); Kenis, Paul J.A. [Institute for Genomic Biology, University of Illinois at Urbana-Champaign, 1206 W. Gregory Drive, Urbana, IL 61801 (United States); Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, 600 S. Mathews Avenue, Urbana, IL 61801 (United States); Rex Gaskins, H. [Institute for Genomic Biology, University of Illinois at Urbana-Champaign, 1206 W. Gregory Drive, Urbana, IL 61801 (United States); Department of Animal Sciences, University of Illinois at Urbana-Champaign, 1207 W. Gregory Drive, Urbana, IL 61801 (United States); Department of Pathobiology, University of Illinois at Urbana-Champaign, 2001 S. Lincoln Avenue, Urbana, IL 61801 (United States); Division of Nutritional Sciences, University of Illinois at Urbana-Champaign, 905 S. Goodwin Avenue, Urbana, IL 61801 (United States)

    2013-10-04

    Highlights: •Time-resolved live cell imaging revealed light-induced oxidation. •Only the roGFP probe fused with glutaredoxin reveals photooxidation. •The transient oxidation is rapidly reduced by the cytosolic antioxidant system. •Intracellular photooxidation is media-dependent. •Oxidation is triggered exclusively by exposure to short wavelength excitation. -- Abstract: We have implemented a ratiometric, genetically encoded redox-sensitive green fluorescent protein fused to human glutaredoxin (Grx1-roGFP2) to monitor real time intracellular glutathione redox potentials of mammalian cells. This probe enabled detection of media-dependent oxidation of the cytosol triggered by short wavelength excitation. The transient nature of light-induced oxidation was revealed by time-lapse live cell imaging when time intervals of less than 30 s were implemented. In contrast, transient ROS generation was not observed with the parental roGFP2 probe without Grx1, which exhibits slower thiol-disulfide exchange. These data demonstrate that the enhanced sensitivity of the Grx1-roGFP2 fusion protein enables the detection of short-lived ROS in living cells. The superior sensitivity of Grx1-roGFP2, however, also enhances responsiveness to environmental cues introducing a greater likelihood of false positive results during image acquisition.

  9. Insect photoperiodism: measuring the night.

    Science.gov (United States)

    Saunders, D S

    2013-01-01

    In studies of photoperiodic induction of over-wintering diapause, independent variation of the light (L) and dark (D) components of the daily (LD) cycle shows, with few exceptions, that the duration of the night (D) is more important than that of the day (L). Extensions of D to give cycle lengths up to 3 days or more in so-called Nanda-Hamner (NH) experiments suggest that night length is measured repeatedly in the extended night, with peaks of high diapause incidence occurring at intervals close to 24 h. This indicates a circadian involvement in night length measurement. The circadian oscillation revealed in NH experiments is shown to take its principal time cue from the beginning of the night - at a phase close to Circadian time, CT 12 - in series of such experiments with increasing light (L) components, in a manner comparable to other circadian oscillations such as that controlling the adult eclosion rhythm. It is considered that the photoperiodic circadian oscillation is causally involved in the discrimination between short (summer) and long (autumnal) nights, although further 'downstream' actions of the circadian system on the outcome of time measurement are also likely. Therefore Bünning's original hypothesis - or development of it - is considered to offer the most likely explanation for the photoperiodic mechanism. Copyright © 2012 Elsevier Ltd. All rights reserved.

  10. Development and testing of highway storm-sewer flow measurement and recording system

    Science.gov (United States)

    Kilpatrick, F.A.; Kaehrle, W.R.; Hardee, Jack; Cordes, E.H.; Landers, M.N.

    1985-01-01

    A comprehensive study and development of measuring instruments and techniques for measuring all components of flow in a storm-sewer drainage system was undertaken by the U.S. Geological Survey under the sponsorship of the Federal Highway Administration. The study involved laboratory and field calibration and testing of measuring flumes, pipe insert meters, weirs, electromagnetic velocity meters as well as the development and calibration of pneumatic-bubbler pressure transducer head measuring systems. Tracer-dilution and acoustic flow meter measurements were used in field verification tests. A single micrologger was used to record data from all the above instruments as well as from a tipping-bucket rain gage and also to activate on command the electromagnetic velocity meter and tracer-dilution systems. (Author 's abstract)

  11. Power Curve Measurements REWS

    DEFF Research Database (Denmark)

    Gómez Arranz, Paula; Vesth, Allan

    This report describes the power curve measurements carried out on a given wind turbine in a chosen period. The measurements were carried out following the measurement procedure in the draft of IEC 61400-12-1 Ed.2 [1], with some deviations mostly regarding uncertainty calculation. Here, the refere......This report describes the power curve measurements carried out on a given wind turbine in a chosen period. The measurements were carried out following the measurement procedure in the draft of IEC 61400-12-1 Ed.2 [1], with some deviations mostly regarding uncertainty calculation. Here......, the reference wind speed used in the power curve is the equivalent wind speed obtained from lidar measurements at several heights between lower and upper blade tip, in combination with a hub height meteorological mast. The measurements have been performed using DTU’s measurement equipment, the analysis...

  12. REVEAL: Reconstruction, Enhancement, Visualization, and Ergonomic Assessment for Laparoscopy

    Science.gov (United States)

    2008-08-01

    perform the measurement. Using a stereoscopic laparoscope and real-time reconstruction of the three-dimensional anatomy allows such measurements to...internal forces generated by ligaments (anterior and posterior cruciate and medial and lateral collateral ligaments) and muscles (quadriceps, hamstring

  13. Investigations on precursor measures for aeroelastic flutter

    Science.gov (United States)

    Venkatramani, J.; Sarkar, Sunetra; Gupta, Sayan

    2018-04-01

    Wind tunnel experiments carried out on a pitch-plunge aeroelastic system in the presence of fluctuating flows reveal that flutter instability is presaged by a regime of intermittency. It is observed that as the flow speed gradually increases towards the flutter speed, there appears intermittent bursts of periodic oscillations which become more frequent as the wind speed increases and eventually the dynamics transition into fully developed limit cycle oscillations, marking the onset of flutter. The signature from these intermittent oscillations are exploited to develop measures that forewarn a transition to flutter and can serve as precursors. This study investigates a suite of measures that are obtained directly from the time history of measurements and are hence model independent. The dependence of these precursors on the size of the measured data set and the time required for their computation is investigated. These measures can be useful in structural health monitoring of aeroelastic structures.

  14. Measuring elderly dysphagic patients' performance in eating--a review

    DEFF Research Database (Denmark)

    Hansen, Tina; Kjaersgaard, Annette; Faber, Jens

    2011-01-01

    Purpose. This review aims to identify psychometrically robust assessment tools suitable for measuring elderly dysphagic patients' performance in eating for use in clinical practice and research. Method. Electronic databases, related citations and references were searched to identify assessment...... tools integrating the complexity of the eating process. Papers were selected according to criteria defined a priori. Data were extracted regarding characteristics of the assessment tools and the evidence of reliability, validity and responsiveness. Quality appraisal was undertaken using developed...... of neurological and geriatric conditions. The rigor of the assessment tools' psychometric properties varied from no evidence available to excellent evidence. Only two assessment tools were rated adequate to excellent. Conclusion. ‘The Minimal Eating Observation Form-Version II’ to be used for screening and ‘The...

  15. Radon measurements by track detectors in Calabrian workplaces

    International Nuclear Information System (INIS)

    Nastro, V.; Niceforo, G.; Vuono, D.; Luca, P. de; Nastro, A.

    2006-01-01

    Indoor radon studies have been carried out in some workplaces of the South Calabria (Italy) by track detectors CR-39. This study has been undertaken for the purpose of safeguarding the public healthy: since the European population spends, in average, the most greater part of their time in confined environments(residences and offices) the risks of exposure can be elevated. This radon passive measurements are been effectuated according to the recommendations. The exposure time in the workplaces was two different cycle: three months, and six months. The obtained results indicate a radon concentration not only in an average of low level but also in the range of action level (>500 Bq/m 3 ). In this last case will be necessary to reduce the radon pollution by adequate land operation works, and a continuous monitoring is also necessary

  16. ACAMS - Integrated Software for Accelerator Alignment and Measurement

    International Nuclear Information System (INIS)

    Curtis, Christopher; Tremblay, Kelly; Baggett, Kenneth

    2002-01-01

    ACAMS (Accelerator Combined Alignment and Measurement System) is a software package that has been developed at Thomas Jefferson National Accelerator Facility (Jefferson Lab). ACAMS was developed to replace four MS-Dos based software programs. These programs operated independently and commonly used theodolite observations as the basis for data collection. The methodology used to collect the data had similarities, but there were inconsistencies and shortcomings in these various processes. ACAMS integrates all the reductions, adjustment and reporting into one package. Jefferson Lab Alignment Group now relies on ACAMS for most of the field surveys undertaken. Many new features that were lacking in the older packages have been included in the development of ACAMS. This paper will discuss the reasoning behind the development, currently available features, and the future direction that the software will take.

  17. Delayed neutron measurements for 232Th neutron-induced fission

    Science.gov (United States)

    Ledoux, X.; Doré, D.; Mosconi, M.; Nolte, R.; Roettger, S.

    2010-10-01

    Delayed neutrons (DN) play an important role in nuclear reactor physics. Innovative critical reactor studies bring to light the need of new DN yields data. For the Th fuel cycle, according to the OECD recommendation, DN of the 232Th is needed with an accuracy of 5%. In the literature, significant discrepancies were observed for energies below 4 MeV and data are dispersed around 14 MeV. Therefore, a programme has been undertaken by CEA in order to measure DN yields from 232Th with incident neutron energies from 2 to 16 MeV. In this paper, the experimental setup will be described and preliminary results obtained at the PTB Ion Accelerator Facility of Braunschweig for incident neutron beam energies of 2, 3, 4, 6, 7, 10 and 16 MeV will be presented.

  18. Altered anatomical network in early blindness revealed by diffusion tensor tractography.

    Directory of Open Access Journals (Sweden)

    Ni Shu

    Full Text Available The topological architecture of the cerebral anatomical network reflects the structural organization of the human brain. Recently, topological measures based on graph theory have provided new approaches for quantifying large-scale anatomical networks. Diffusion MRI studies have revealed the efficient small-world properties and modular structure of the anatomical network in normal subjects. However, no previous study has used diffusion MRI to reveal changes in the brain anatomical network in early blindness. Here, we utilized diffusion tensor imaging to construct binary anatomical networks for 17 early blind subjects and 17 age- and gender-matched sighted controls. We established the existence of structural connections between any pair of the 90 cortical and sub-cortical regions using deterministic tractography. Compared with controls, early blind subjects showed a decreased degree of connectivity, a reduced global efficiency, and an increased characteristic path length in their brain anatomical network, especially in the visual cortex. Moreover, we revealed some regions with motor or somatosensory function have increased connections with other brain regions in the early blind, which suggested experience-dependent compensatory plasticity. This study is the first to show alterations in the topological properties of the anatomical network in early blindness. From the results, we suggest that analyzing the brain's anatomical network obtained using diffusion MRI data provides new insights into the understanding of the brain's re-organization in the specific population with early visual deprivation.

  19. Controlled preparation of wet granular media reveals limits to lizard burial ability

    Science.gov (United States)

    Sharpe, Sarah S.; Kuckuk, Robyn; Goldman, Daniel I.

    2015-07-01

    Many animals move within ground composed of granular media (GM); the resistive properties of such substrates can depend on water content and compaction, but little is known about how such parameters affect locomotion or the physics of drag and penetration. Using apparatus to control compaction of GM, our recent studies of movement in dry GM have revealed locomotion strategies of specialized dry-sand-swimming reptiles. However, these animals represent a small fraction of the diversity and presumed burial strategies of fossorial reptilian fauna. Here we develop a system to create states of wet GM of varying moisture content and compaction in quantities sufficient to study the burial and subsurface locomotion of the Ocellated skink (C. ocellatus), a generalist lizard. X-ray imaging revealed that in wet and dry GM the lizard slowly buried (≈ 30 s) propagating a wave from head to tail, while moving in a start-stop motion. During forward movement, the head oscillated, and the forelimb on the convex side of the body propelled the animal. Although body kinematics and ‘slip’ were similar in both substrates, the burial depth was smaller in wet GM. Penetration and drag force experiments on smooth cylinders revealed that wet GM was ≈ 4× more resistive than dry GM. In total, our measurements indicate that while the rheology of the dry and wet GM differ substantially, the lizard's burial motor pattern is conserved across substrates, while its burial depth is largely constrained by environmental resistance.

  20. Neural correlates reveal sub-lexical orthography and phonology during reading aloud: A review

    Directory of Open Access Journals (Sweden)

    Kalinka eTimmer

    2014-08-01

    Full Text Available The sub-lexical conversion of graphemes-to-phonemes (GPC during reading has been investigated extensively with behavioral measures, as well as event-related potentials (ERPs. Most research utilizes silent reading (e.g., lexical decision task for which phonological activation is not a necessity. However, recent research employed reading aloud to capture sub-lexical GPC. The masked priming paradigm avoids strategic processing and is therefore well suitable for capturing sub-lexical processing instead of lexical effects. By employing ERPs, the on-line time course of sub-lexical GPC can be observed before the overt response. ERPs have revealed that besides phonological activation, as revealed by behavioral studies, there is also early orthographic activation. This review describes studies in one’s native language, in one’s second language, and in a cross-language situation. We discuss the implications the ERP results have on different (computational models. First, the ERP results show that computational models should assume an early locus of the grapheme-to-phoneme-conversion (GPC. Second, cross-language studies reveal that the phonological representations from both languages of a bilingual become activated automatically and the phonology belonging to the context is selected rapidly. Therefore, it is important to extend the scope of computational models of reading (aloud to multiple lexicons.