WorldWideScience

Sample records for understands individual development

  1. Career Development Practitioners as Advocates for Transgender Individuals: Understanding Gender Transition

    Science.gov (United States)

    Sangganjanavanich, Varunee Faii

    2009-01-01

    Assisting transgender individuals is a concern for career development practitioners because there is a lack of knowledge on this topic. The complexity of gender reassignment surgery brings challenges and unique needs to this population, throughout gender transition, and requires career development practitioners to understand these challenges and…

  2. Understanding individual routing behaviour.

    Science.gov (United States)

    Lima, Antonio; Stanojevic, Rade; Papagiannaki, Dina; Rodriguez, Pablo; González, Marta C

    2016-03-01

    Knowing how individuals move between places is fundamental to advance our understanding of human mobility (González et al. 2008 Nature 453, 779-782. (doi:10.1038/nature06958)), improve our urban infrastructure (Prato 2009 J. Choice Model. 2, 65-100. (doi:10.1016/S1755-5345(13)70005-8)) and drive the development of transportation systems. Current route-choice models that are used in transportation planning are based on the widely accepted assumption that people follow the minimum cost path (Wardrop 1952 Proc. Inst. Civ. Eng. 1, 325-362. (doi:10.1680/ipeds.1952.11362)), despite little empirical support. Fine-grained location traces collected by smart devices give us today an unprecedented opportunity to learn how citizens organize their travel plans into a set of routes, and how similar behaviour patterns emerge among distinct individual choices. Here we study 92 419 anonymized GPS trajectories describing the movement of personal cars over an 18-month period. We group user trips by origin-destination and we find that most drivers use a small number of routes for their routine journeys, and tend to have a preferred route for frequent trips. In contrast to the cost minimization assumption, we also find that a significant fraction of drivers' routes are not optimal. We present a spatial probability distribution that bounds the route selection space within an ellipse, having the origin and the destination as focal points, characterized by high eccentricity independent of the scale. While individual routing choices are not captured by path optimization, their spatial bounds are similar, even for trips performed by distinct individuals and at various scales. These basic discoveries can inform realistic route-choice models that are not based on optimization, having an impact on several applications, such as infrastructure planning, routing recommendation systems and new mobility solutions. © 2016 The Author(s).

  3. The Development of Children's Moral Sensibility: Individual Differences and Emotion Understanding.

    Science.gov (United States)

    Dunn, Judy; And Others

    1995-01-01

    Developmental changes and individual differences in children's conceptions of transgression were studied in 46 children from preschool through 1st grade. Differences in response to moral transgressions in kindergarten were related to mothers' control management and to siblings' friendly behavior in the preschool period, early understanding of…

  4. Ayurgenomics: Understanding human individuality through ...

    Indian Academy of Sciences (India)

    mitali

    Ayurgenomics: Understanding human individuality through integration of. Ayurveda and Genomics for stratified medicine. Mitali Mukerji. Programme Director- CSIR-TRISUTRA. (Translational Research and Innovative Science Through Ayurgenomics). & Scientist CSIR-IGIB. Public health Modern medicine. Ayurveda others ...

  5. Understanding the Relationship between Moral Judgment Development and Individual Characteristics: The Role of Educational Contexts

    Science.gov (United States)

    Maeda, Yukiko; Thoma, Steve J.; Bebeau, Muriel J.

    2009-01-01

    This study examines variation in moral judgment level as measured by the Defining Issues Test 2 (DIT-2; J. R. Rest & D. Narvaez, 1998), based on individual demographic information and educational contexts. Individual DIT-2 scores and demographic information were obtained from the archived data sets housed at the Center for the Study of Ethical…

  6. Understanding individual human mobility patterns.

    Science.gov (United States)

    González, Marta C; Hidalgo, César A; Barabási, Albert-László

    2008-06-05

    Despite their importance for urban planning, traffic forecasting and the spread of biological and mobile viruses, our understanding of the basic laws governing human motion remains limited owing to the lack of tools to monitor the time-resolved location of individuals. Here we study the trajectory of 100,000 anonymized mobile phone users whose position is tracked for a six-month period. We find that, in contrast with the random trajectories predicted by the prevailing Lévy flight and random walk models, human trajectories show a high degree of temporal and spatial regularity, each individual being characterized by a time-independent characteristic travel distance and a significant probability to return to a few highly frequented locations. After correcting for differences in travel distances and the inherent anisotropy of each trajectory, the individual travel patterns collapse into a single spatial probability distribution, indicating that, despite the diversity of their travel history, humans follow simple reproducible patterns. This inherent similarity in travel patterns could impact all phenomena driven by human mobility, from epidemic prevention to emergency response, urban planning and agent-based modelling.

  7. Can Children Construct Inverse Relations in Arithmetic? Evidence for Individual Differences in the Development of Conceptual Understanding and Computational Skill

    Science.gov (United States)

    Gilmore, Camilla K.; Bryant, Peter

    2008-01-01

    Understanding conceptual relationships is an important aspect of learning arithmetic. Most studies of arithmetic, however, do not distinguish between children's understanding of a concept and their ability to identify situations in which it might be relevant. We compared 8- to 9-year-old children's use of a computational shortcut based on the…

  8. Understanding users in product development

    DEFF Research Database (Denmark)

    Geert Jensen, Birgitte

    2012-01-01

    , the guideline contain a step by step process to develop easy‐to‐open packaging. The guideline is constructed in a way that allows the enterprise to pick and choose in respect to the enterprise´s needs and competences. The main focus in the development of the guidelines has been to produce a tool that function...... observations is a tool for user understanding and that the first step towards better packaging, goes through consensus in the organization regarding the need for more easy‐opening packaging....

  9. Imaging Brain Development: Benefiting from Individual Variability

    Directory of Open Access Journals (Sweden)

    Megha Sharda

    2015-01-01

    Full Text Available Human brain development is a complex process that evolves from early childhood to young adulthood. Major advances in brain imaging are increasingly being used to characterize the developing brain. These advances have further helped to elucidate the dynamic maturational processes that lead to the emergence of complex cognitive abilities in both typical and atypical development. However, conventional approaches involve categorical group comparison models and tend to disregard the role of widespread interindividual variability in brain development. This review highlights how this variability can inform our understanding of developmental processes. The latest studies in the field of brain development are reviewed, with a particular focus on the role of individual variability and the consequent heterogeneity in brain structural and functional development. This review also highlights how such heterogeneity might be utilized to inform our understanding of complex neuropsychiatric disorders and recommends the use of more dimensional approaches to study brain development.

  10. Individual differences in children's emotion understanding: Effects of age and language

    DEFF Research Database (Denmark)

    Pons, Francisco; Lawson, J.: Harris, P.; Rosnay, M. de

    2003-01-01

    Over the last two decades, it has been established that children's emotion understanding changes as they develop. Recent studies have also begun to address individual differences in children's emotion understanding. The first goal of this study was to examine the development of these individual...... differences across a wide age range with a test assessing nine different components of emotion understanding. The second goal was to examine the relation between language ability and individual differences in emotion understanding. Eighty children ranging in age from 4 to 11 years were tested. Children...... displayed a clear improvement with age in both their emotion understanding and language ability. In each age group, there were clear individual differences in emotion understanding and language ability. Age and language ability together explained 72% of emotion understanding variance; 20% of this variance...

  11. Developmental and Individual Differences in Understanding of Fractions

    Science.gov (United States)

    Siegler, Robert S.; Pyke, Aryn A.

    2013-01-01

    We examined developmental and individual differences in 6th and 8th graders' fraction arithmetic and overall mathematics achievement and related them to differences in understanding of fraction magnitudes, whole number division, executive functioning, and metacognitive judgments within a crosssectional design. Results indicated that the difference…

  12. Sources of Individual Differences in Children's Understanding of Fractions

    Science.gov (United States)

    Vukovic, Rose K.; Fuchs, Lynn S.; Geary, David C.; Jordan, Nancy C.; Gersten, Russell; Siegler, Robert S.

    2014-01-01

    Longitudinal associations of domain-general and numerical competencies with individual differences in children's understanding of fractions were investigated. Children (n = 163) were assessed at 6 years of age on domain-general (nonverbal reasoning, language, attentive behavior, executive control, visual-spatial memory) and numerical (number…

  13. Understanding of the Impact of Leadership Development

    DEFF Research Database (Denmark)

    Sørensen, Peter

    2017-01-01

    Leadership development is big business. But the size of the investment notwithstanding, it has been pointed out that the programs and activities devoted to leadership development are often based on little more than anecdotes, personal experience, and guesses about what might be effective......—for the individual and for the organization. In other words, leadership development can too often be an act of blind faith. In this blog I report on my preliminary work on understanding the conditions that might affect the impact of leadership development initiatives....

  14. The importance of understanding individual differences in Down syndrome

    Science.gov (United States)

    Karmiloff-Smith, Annette; Al-Janabi, Tamara; D'Souza, Hana; Groet, Jurgen; Massand, Esha; Mok, Kin; Startin, Carla; Fisher, Elizabeth; Hardy, John; Nizetic, Dean; Tybulewicz, Victor; Strydom, Andre

    2016-01-01

    In this article, we first present a summary of the general assumptions about Down syndrome (DS) still to be found in the literature. We go on to show how new research has modified these assumptions, pointing to a wide range of individual differences at every level of description. We argue that, in the context of significant increases in DS life expectancy, a focus on individual differences in trisomy 21 at all levels—genetic, cellular, neural, cognitive, behavioral, and environmental—constitutes one of the best approaches for understanding genotype/phenotype relations in DS and for exploring risk and protective factors for Alzheimer’s disease in this high-risk population. PMID:27019699

  15. Strengthening Community with Individual Development.

    Science.gov (United States)

    Erb, Tom

    1998-01-01

    Explores how the middle school concept is designed to make two seemingly contradictory goals compatible, those of providing a common core curriculum while meeting individual needs. Suggests that, similar to team sports or musical groups, it is possible to allow students to exercise personalized choices of how to meet the common objectives of the…

  16. Developmental and Individual Differences in Understanding of Fractions

    Science.gov (United States)

    Siegler, Robert S.; Pyke, Aryn A.

    2014-01-01

    We examined developmental and individual differences in 6th and 8th graders’ fraction arithmetic and overall mathematics achievement and related them to differences in understanding of fraction magnitudes, whole number division, executive functioning, and metacognitive judgments within a cross sectional design. Results indicated that the difference between low achieving and higher achieving children’s fraction arithmetic knowledge, already substantial in 6th grade, was much greater in 8th grade. The fraction arithmetic knowledge of low achieving children was similar in the two grades, whereas higher achieving children showed much greater knowledge in 8th than 6th grade, despite both groups having been in the same classrooms, using the same textbooks, and having the same teachers and classmates. Individual differences in both fraction arithmetic and mathematics achievement test scores were predicted by differences in fraction magnitude knowledge and whole number division, even after the contributions of reading achievement and executive functioning were statistically controlled. Instructional implications of the findings are discussed. PMID:23244401

  17. Ausubel's understanding of concept development

    Directory of Open Access Journals (Sweden)

    Janković Aleksandar P.

    2015-01-01

    Full Text Available This paper presents one of relatively new cognitivistic learning and cognition theories - the theory by American psychologist David Ausubel. We consider this theory to be very usable for teaching beginners or for cognition process. It is of utmost importance that first or elementary concepts concerning natural and social phenomena a pupil aquires need to be accurate, understandable and properly connected in a cause-effect sequence of conceptual systems so that items of knowledge aquired can be stable and usable. For correct understanding of Ausubel's claims concerning processes and procedures involved in the acquisition of elementary concepts, which is central to this investigation, it is necessary to address problems and questions concerning the following: the process of aquisition or construction of first concepts; how to base verbal learning; how is subsuming achieved, that is connecting of new and previously acquired concepts; what is the relation of this theory with other cognitivistic theories of learning, and, finally, what are critical views or evalutions which can make this theory truly productive in relation to teaching.

  18. Understanding users in product development

    DEFF Research Database (Denmark)

    Geert Jensen, Birgitte

    2012-01-01

    Abstract: The consumers expect the packaging to be functional and to fulfil their specific needs in every way. A Danish survey showed that at least 40 per cent experience difficulties, when handling and opening packaging at least once a month, and as a consequence, 16 per cent of the consumers......, the guideline contain a step by step process to develop easy‐to‐open packaging. The guideline is constructed in a way that allows the enterprise to pick and choose in respect to the enterprise´s needs and competences. The main focus in the development of the guidelines has been to produce a tool that function...

  19. Understanding individual differences in word recognition skills of ESL children.

    Science.gov (United States)

    Geva, E; Yaghoub-Zadeh, Z; Schuster, B

    2000-01-01

    This paper focuses on the extent to which the development of ESL (English as a Second Language) word recognition skills mimics similar trajectories in same-aged EL1 (English as a First Language) children, and the extent to which phonological processing skills and rapid naming can be used to predict word recognition performance in ESL children. Two cohorts of Grade 1 ESL and EL1 primary-level children were followed for two consecutive years. Results indicated that vocabulary knowledge, a measure of language proficiency, and nonverbal intelligence were not significant predictors of word recognition in either group. Yet, by considering individual differences in phonological awareness and rapid naming, it was possible to predict substantial amounts of variance on word recognition performance six months and one year later in both language groups. Commonality analyses indicated that phonological awareness and rapid naming contributed unique variance to word recognition performance. Moreover, the profiles of not at-risk children in the EL1 and ESL groups were similar on all but the oral language measure, where EL1 children had the advantage. In addition, EL1 and ESL profiles of children who had word-recognition difficulty were similar, with low performance on rapid naming and phonological awareness. Results indicate that these measures are reliable indicators of potential reading disability among ESL children.

  20. Understanding the Everyday Practice of Individualized Education Program Team Members

    Science.gov (United States)

    Hartmann, Elizabeth S.

    2016-01-01

    The Individuals with Disabilities Education Improvement Act of 2004 states that individualized education program (IEP) teams are composed of members with distinct identities, roles, expertise, and histories. Although team members must work together to implement educational and related services for learners with special needs, little is known about…

  1. Exploring educators' understanding of developing learners' reading ...

    African Journals Online (AJOL)

    Exploring educators' understanding of developing learners' reading skills and their readiness to implement CAPS. ... Journal for Language Teaching ... Phase English First Additional Language teachers understood about reading and teaching reading, and the strategies they used to develop learners' reading skills.

  2. Understanding the Role of Cultural Intelligence in Individual Creativity

    Science.gov (United States)

    Yunlu, Dilek G.; Clapp-Smith, Rachel; Shaffer, Margaret

    2017-01-01

    Employing creative cognition theory, this study investigates the relationship between cultural intelligence (CQ) and creativity. Using data from 394 full-time employees, metacognitive, cognitive, and motivational forms of CQ were found to have positive relationships with individual creativity. In addition, the positive effect of cognitive CQ on…

  3. Individual Freedom and Institutional Frameworks in Development

    Science.gov (United States)

    Allen, Nicholas

    2012-01-01

    In this article I explore Amartya Sen's contention that individual freedom represents both the objective of development and the means through which development is to take place. Examining the conceptualisation of freedom central to Sen's capability approach, I distinguish between two notions of freedom, autonomy and agency, where the former…

  4. Understanding and predicting students' dishonesty: development of ...

    African Journals Online (AJOL)

    Results show that the measure that we developed is a valid predictor of a person's level of honesty and has significant correlations with other well known and validated measures of such personality profiles. Secondly, we hypothesised that individuals with low levels of socialisation, as measured by Gough's 1987 revised ...

  5. Annotation: Understanding the Development of Psychopathy

    Science.gov (United States)

    Viding, Essi

    2004-01-01

    Background: Psychopaths are not only antisocial, but also have a callous and unemotional personality profile. This article selectively reviews evidence that psychopathic personality traits are an important factor in understanding and predicting the development of persistent antisocial conduct. Cognitive neuroscience research and more tentative…

  6. Poor understanding? Challenges to Global Development Education

    Directory of Open Access Journals (Sweden)

    John Buchanan

    2018-03-01

    Full Text Available As members of a global community, we cohabit a metaphorically shrinking physical environment, and are increasingly connected one to another, and to the world, by ties of culture, economics, politics, communication and the like. Education is an essential component in addressing inequalities and injustices concerning global rights and responsibilities. The increasing multicultural nature of societies locally, enhanced access to distal information, and the work of charitable organisations worldwide are some of the factors that have contributed to the interest in, and need for, understanding global development education. The project on which this paper reports sought answers to the question: to what extent and in what ways can a semester-long subject enhance and extend teacher education students’ understandings of and responses to global inequalities and global development aid? In the course of the project, a continuum model emerged, as follows: Indifference or ignorance ➝ pity and charity ➝ partnership and development among equals. In particular, this paper reports on some of the challenges and obstacles that need to be addressed in order to enhance pre-service teachers’ understandings of global development education. The study, conducted in Australia, has implications for global development education in other developed nations.

  7. Avoiding Substantive Errors in Individualized Education Program Development

    Science.gov (United States)

    Yell, Mitchell L.; Katsiyannis, Antonis; Ennis, Robin Parks; Losinski, Mickey; Christle, Christine A.

    2016-01-01

    The purpose of this article is to discuss major substantive errors that school personnel may make when developing students' Individualized Education Programs (IEPs). School IEP team members need to understand the importance of the procedural and substantive requirements of the IEP, have an awareness of the five serious substantive errors that IEP…

  8. Separation-Individuation in Female Adult Development.

    Science.gov (United States)

    Mullins, Deborah

    This study examined separation-individuation development issues for young adult women, from the perspective of object-relations theory. Its purpose was to explore a woman's perception of her relationship with mother as it is affected by age and request for psychotherapy as well as the relationship between mother-daughter bond and personality…

  9. Individual moral development and moral progress

    NARCIS (Netherlands)

    Schinkel, Anders; de Ruyter, Doret J.

    At first glance, one of the most obvious places to look for moral progress is in individuals, in particular in moral development from childhood to adulthood. In fact, that moral progress is possible is a foundational assumption of moral education. Beyond the general agreement that moral progress is

  10. Individual Moral Development and Moral Progress

    NARCIS (Netherlands)

    Schinkel, Anders; de Ruyter, Doret J.

    2017-01-01

    At first glance, one of the most obvious places to look for moral progress is in individuals, in particular in moral development from childhood to adulthood. In fact, that moral progress is possible is a foundational assumption of moral education. Beyond the general agreement that moral progress is

  11. Understanding physical activity in individuals with prediabetes: an application of social cognitive theory.

    Science.gov (United States)

    Taylor, Lorian M; Raine, Kim D; Plotnikoff, Ronald C; Vallance, Jeff K; Sharma, Arya M; Spence, John C

    2016-01-01

    Despite well-documented evidence implicating physical activity (PA) in the prevention of type 2 diabetes, the overwhelming majority of individuals with prediabetes are not physically active enough. The purpose of this study was to investigate the applicability of the social cognitive theory (SCT) in understanding PA behaviour in individuals with prediabetes. Individuals with prediabetes (N = 232) completed a mailed questionnaire assessing demographics, self-reported PA (MET.min/wk) and SCT constructs for PA MET.min/wk. For PA MET.min/wk, scheduling and task efficacy both had significant effects on PA (β = .30 and .22, respectively). Goal formation also had a direct effect on PA for scheduling, coping and task efficacy (β = .20, .34 and .30, respectively). Task, coping and scheduling efficacy explained a significant portion of the variance in PA behaviour. Overall, SCT appears to have merit as a model for understanding PA in individuals with prediabetes. Further evaluative inquiry is needed to establish support for the use of the SCT as a framework for developing, implementing and evaluating PA behaviour change interventions in this population.

  12. A neurogenetics approach to understanding individual differences in brain, behavior, and risk for psychopathology.

    Science.gov (United States)

    Bogdan, R; Hyde, L W; Hariri, A R

    2013-03-01

    Neurogenetics research has begun to advance our understanding of how genetic variation gives rise to individual differences in brain function, which, in turn, shapes behavior and risk for psychopathology. Despite these advancements, neurogenetics research is currently confronted by three major challenges: (1) conducting research on individual variables with small effects, (2) absence of detailed mechanisms, and (3) a need to translate findings toward greater clinical relevance. In this review, we showcase techniques and developments that address these challenges and highlight the benefits of a neurogenetics approach to understanding brain, behavior and psychopathology. To address the challenge of small effects, we explore approaches including incorporating the environment, modeling epistatic relationships and using multilocus profiles. To address the challenge of mechanism, we explore how non-human animal research, epigenetics research and genome-wide association studies can inform our mechanistic understanding of behaviorally relevant brain function. Finally, to address the challenge of clinical relevance, we examine how neurogenetics research can identify novel therapeutic targets and for whom treatments work best. By addressing these challenges, neurogenetics research is poised to exponentially increase our understanding of how genetic variation interacts with the environment to shape the brain, behavior and risk for psychopathology.

  13. Understanding the development of international environmental agreements

    DEFF Research Database (Denmark)

    Stærdahl, Jens

    There are many different theoretical schools concerned with how international regimes develop, and each supplies its own interpretation focusing on one or a few aspects of the process. Such ‘one shot’ explanations may be fruitful for scientific debate, but less useful as conceptual frameworks...... for practitioners and planners manoeuvring in a complex world. On the basis of a review of selected theories of international and environmental regulation, this article initiates the development of a conceptual framework for understanding the development of internationalenvironmental agreements. The point...... of departure for developing the model is the actor-structure debate within social science and theory of international relations. Based on critical realism, a framework is developed specifying the relation between collective action problem situations and negotiation situations. It is argued that the main...

  14. Understanding the Self in Individuals with Autism Spectrum Disorders (ASD: A Review of Literature

    Directory of Open Access Journals (Sweden)

    Ann X. Huang

    2017-08-01

    Full Text Available When the system of self is explored in individuals with Autism Spectrum Disorders (ASDs, it is important to measure it via both their own perceptions of the self and their understanding of others’ perceptions on themselves at a multidimensional level. This paper reviews existing research in this area using a three-dimension approach. Researchers have found that impairments in the self-system are usually correlated with these individuals’ social and cognitive functioning levels: high functioning individuals with ASD who have higher IQ are found to have better awareness of their limitations in social and communication domains than those with lower IQ. Many researchers believe that there are impairments in the psychological (but not physical self in individuals with ASD, such as theory of mind deficits due to social and communicative impairments. On the other hand, some researchers argue that individuals with ASD have selective rather than global impairments in the self. In other words, the impairment usually lies in a specific aspect of functioning in individuals with ASD. Insights from the review of existing literature on this topic may be able to shed some lights on the development of effective intervention programs to improve social communication deficits in this population.

  15. INDIVIDUALS PERFORMANCE MEASUREMENT IN AGILE SOFTWARE DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    Aref Al-Heyasi

    2018-04-01

    Full Text Available Many organizations in the last years have been shifting to Agile, especially in software development sector, to deliver their projects. Rapid changes in demands, requirements, technologies, and regulations have made it more important for organizations to respond quickly and effectively. Agile provides the flexibility to reconfigure strategies, processes, people, and technologies toward value creation. Agile promises to deliver value through small, potentially shippable product features developed within short iterations. In Agile, there is no one manager who makes all the decisions alone, but all team members participate in making important project decisions. Agile believes that teamwork is essential to deliver high-quality software. The unique characteristics of the team in Agile make it hard to fit with standard HR processes like annual individual performance reviews. This paper introduces the individual performance management in Agile environment and how the annual performance appraisal might not fit with Agile and discusses the alternatives to make a convenient performance evaluation for agile team members.

  16. The Individual Practice Development Theory: an individually focused practice development theory that helps target practice development resources.

    Science.gov (United States)

    Melton, Jane; Forsyth, Kirsty; Freeth, Della

    2012-06-01

    Research indicates that multifaceted practice development (PD) interventions are more effective than single strategies. However, models of education in health care need to consider cost-effectiveness. This paper presents a research-based, PD theory called the Individual Practice Development Theory. It argues that programmes that use the Individual Practice Development Theory to tailor PD support to the learning needs of practitioners will result in more engagement in PD and will target PD resources efficiently. The in-depth qualitative, multi-method realistic evaluation was of a multifaceted, organization-wide PD programme in one National Health Service Mental Health and Learning Disabilities Trust. Semi-structured interviews, practice observation and documentation audit were used to gather data from occupational therapists. Results indicated that environmental contexts, particularly the support of the immediate team, and the participant's personal circumstances affected PD behaviour change. Six mechanisms acted as catalysts. These were: Building Confidence, Finding Flow, Accumulating Reward, Conferring with Others, Constructing Knowledge Know-how and Channelling Time. Four stages of PD characterized as: 'In the Hangar', 'On the Runway', 'Take-off' and 'In the Air' were identified. The research also illustrated the interconnectivity between outcome levels, contextual circumstances and activating mechanisms. The findings suggested that PD interventions need to be more individually tailored to achieve optimum learning outcomes. The identification of four discernable stages permits rapid understanding of PD support needs in order to focus PD support. With a systematic and individualized approach to PD in health care, more target PD supports can be put in place. © 2011 Blackwell Publishing Ltd.

  17. Development of operation individual dosimetry programs in a developing country

    International Nuclear Information System (INIS)

    Sohrabi, M.

    1993-01-01

    Development of Operational Individual Dosimetry (OID) Programs is the principle rationale for any national radiation protection regulatory program in both developed and developing countries. Individual dosimetry for external radiation means making exposure measurements by equipment carried out on the persons or workers. An operational individual dosimetry (OID) program is defined as development of a program in an operational state to provide national or institutional dosimetry services; i.e. to cover routine, operational and special monitoring as defined by ICRP 35. The development of an OID program depends on many legal, administrative, psychological and technical factors such as number of institutions and radiation workers or persons to be monitored, radiation types and conditions of the workplaces, the state of related sciences and technologies, radiation protection infrastructure as regard to laws and regulations, the existence of qualified leader and manpower, desire to develop such a program, degree of self-dependency required, etc. Although development of such a program is fairly easy with a proper arrangement, some problems still exist in particular in a developing country. In this paper, the stated points and recommendations for development of OID programs in developing countries based on the experiences of the Islamic Republic of Iran and some other countries are presented and discussed. (author). 32 refs

  18. Individual shareholders’ understanding of the content of interim reports of South African listed retail companies

    Directory of Open Access Journals (Sweden)

    Johan GI Oberholster

    2015-05-01

    Full Text Available A number of studies conducted, and reports published, by international and local accounting bodies have found that the proliferation of disclosures in financial reports has hampered users’ understanding of these reports. The reports by accounting bodies also indicate that these users prefer more concise financial reports. These findings, in conjunction with a dearth of recent questionnaire-based research on whether individual shareholders understand the content of financial reports, resulted in this study on whether individual shareholders understand the content of interim reports. The study provides empirical proof that a sound knowledge of business, accounting and economic matters is a prerequisite for understanding interim reports in the case of individual shareholders. The results of the study indicate that individual shareholders have a limited understanding of the content of interim reports as a whole, and that a good knowledge of business and economic matters and of accounting results in an improved understanding of the content of interim reports. In particular, specialisation in accounting in undergraduate and postgraduate degrees, professional qualifications, and work experience in the financial field improve the understanding of individual shareholders.

  19. Sustainable agriculture: Developing a common understanding for ...

    African Journals Online (AJOL)

    The concept of sustainability has become central to all sectors all over the world, from agriculture to environment to business, engineering and industrialization. The principle of sustainability is the same all over these sectors. However, the understanding of the term may vary from sector to sector depending on how it may be ...

  20. Education practitioners' understanding of professional development ...

    African Journals Online (AJOL)

    The committee of Teacher Education Policy (COTEP) considers the professional development of practitioners as one way to improve the quality of professional practice. An analysis of the literature on professional development in education ...

  1. Individual Differences in Toddlers’ Social Understanding & Prosocial Behavior: Disposition or Socialization?

    Directory of Open Access Journals (Sweden)

    Rebekkah Lauren Gross

    2015-05-01

    Full Text Available We examined how individual differences in social understanding contribute to variability in early-appearing prosocial behavior. Moreover, potential sources of variability in social understanding were explored and examined as additional possible predictors of prosocial behavior. Using a multi-method approach with both observed and parent-report measures, 325 children aged 18 to 30 months were administered measures of social understanding (e.g. use of emotion words; self-understanding, prosocial behavior (in separate tasks measuring instrumental helping, empathic helping, and sharing, as well as parent-reported prosociality at home, temperament (fearfulness, shyness, and social fear, and parental socialization of prosocial behavior in the family. Individual differences in social understanding predicted variability in empathic helping and parent-reported prosociality, but not instrumental helping or sharing. Parental socialization of prosocial behavior was positively associated with toddlers’ social understanding, prosocial behavior at home, and instrumental helping in the lab, and negatively associated with sharing (possibly reflecting parents’ increased efforts to encourage children who were less likely to share. Further, socialization moderated the association between social understanding and prosocial behavior, such that social understanding was less predictive of prosocial behavior among children whose parents took a more active role in socializing their prosociality. None of the dimensions of temperament was associated with either social understanding or prosocial behavior. Parental socialization of prosocial behavior is thus an important source of variability in children’s early prosociality, acting in concert with early differences in social understanding, with different patterns of influence for different subtypes of prosocial behavior.

  2. Patterns of Individual Differences in Conceptual Understanding and Arithmetical Skill: A Meta-Analysis

    Science.gov (United States)

    Gilmore, Camilla K.; Papadatou-Pastou, Marietta

    2009-01-01

    Some theories from cognitive psychology and mathematics education suggest that children's understanding of mathematical concepts develops together with their knowledge of mathematical procedures. However, previous research into children's understanding of the inverse relationship between addition and subtraction suggests that there are individual…

  3. Creating Shared Understanding in Product development Teams

    DEFF Research Database (Denmark)

    Nielsen, Louise Møller; Tollestrup, Christian

    that this situation is part of many projects. Lack of shared understanding or frames is just one of the difficulties facing interdisciplinary design teams working in the early phases of innovation. Besides managing their different values, perspectives and interests that cause them to see different things as important...... and that nobody really understood each other. The situation described above could perhaps be taken out of several different contexts and scenarios. Most people, who have been working in teams, probably recognize it, and especially people with experi-ences from interdisciplinary teams can confirm...... of physical artifacts in a special setting and with a specific set of characteristics is. The objective of this book is to demonstrate how building these particular physical arti¬facts enable and stimulate the communication between team mem¬bers, users and stakeholders in interdisciplinary teams working...

  4. Developing Individual and Team Character in Sport

    Science.gov (United States)

    Gaines, Stacey A.

    2012-01-01

    The idea that participation in sport builds character is a long-standing one. Advocates of sport participation believe that sport provides an appropriate context for the learning of social skills such as cooperation and the development of prosocial behavior (Weiss, Smith, & Stuntz, 2008). Research in sport regarding character development has…

  5. Understanding Technology: Key to Development. | Bvekerwa ...

    African Journals Online (AJOL)

    This paper observes that technology as a concept is not fully understood in the developing world. More often than not technology and science are taken to mean the same thing. It is argued here that the two terms are not synonymous but are actually two sides of the same coin. It is further illustrated that technology is not ...

  6. Understanding Early Sexual Development (For Parents)

    Science.gov (United States)

    ... get both in and out of the home. Preschool (Ages 3 to 5) By preschool, most kids have developed a strong sense of ... swim together. Issues that parents of elementary school-age kids might face include: Bad language. Children will pick up bad language and inappropriate ...

  7. Understanding Preservice Educators' Multicultural Identity Development

    Science.gov (United States)

    Rogers, Audrey Green

    2012-01-01

    This study explored undergraduate teacher candidates' multicultural identity development. Forty-three participants were in two sections of the course Introduction to Education. The research questions investigated the ways in which candidates examine their cultural awareness, knowledge of diverse learners, and effective practices for 21st century…

  8. Understanding and Developing Black Popular Music Collections.

    Science.gov (United States)

    Murray, James Briggs

    1983-01-01

    Enumerates types of black popular music (work songs, spirituals, gospel music, blues, race records, rock and roll, soul, funk, disco, Caribbean, and African) and discusses collection development (current, retrospective, monographs, periodicals, sheet music, motion picture film, photographs, oral history), cataloging, and preservation. A 229-item…

  9. Developing Conceptual Understanding in Primary Science.

    Science.gov (United States)

    Asoko, Hilary

    2002-01-01

    Outlines general guidelines for teaching conceptual development in science in the United Kingdom. Focuses on the introduction of new ideas in the primary classroom. Uses two examples of teaching to exemplify how relevant ideas of science can be introduced. Discusses the teacher's role in talking ideas into existence. (BT)

  10. Understanding of the Impact of Leadership Development

    DEFF Research Database (Denmark)

    Sørensen, Peter

    2017-01-01

    and for the organization. I did some preliminary research about what conditions in the workplace may promote the impact of leadership development. In my study of managers in the Danish public sector, I looked at nine possible conditions that the transfer literature suggested were likely to be important in this...

  11. Understanding and developing creativity: A practical approach

    OpenAIRE

    Donald J. Treffinger; Edwin C. Selby

    2008-01-01

    Critical thinking and creative thinking are proposed as determinants to cope with the constant change society, and basically children are experiencing nowadays. Moreover, tools for the development of critical and creative thinking are discussed, and the creative problem solving toolbox is presented, involving tools for generating options, as well as tools for focusing options. The importance of the tools as significant basis for the learning process, as well as for the management of changes i...

  12. Image Understanding Architecture Prototype Evaluation and Development

    Science.gov (United States)

    1993-06-01

    2n. We have developed an algorithm (the MGRA discussed below), based on wormhole routing, that has routed a large number of communication patterns...inference and manipulation of object models are run in the SPA. To support distributed artificial intelligence processing, powerful processors are needed... artificial intelligence. A typical scenario with video input I might require that an interpretation of a changing scene be updated as video frames arrive

  13. Understanding the population dimension in development planning.

    Science.gov (United States)

    Rivera, P C

    1983-01-01

    In the Philippines initial efforts to adopt population policies focused on reducing rapid population growth through fertility control. The history of the national population welfare congress, which started in 1978, reflects this emphasis on family planning as a major deterrent to rapid population growth. It was only in recent years that the 2-way relationship between population and development came to be better appreciated. The 6th National Populaton Welfare Congress was a response to this need to broaden the scope of population concerns and integrate the population dimension into development planning. This viewpoint regards population not as a demand variable but as a factor that can be influenced by economic and social development. Dr. Mercedes B. Concepcion, dean of the University of the Philippines Population Institute (UPPI), discussed population trends, prospects, and problems in a paper presented before the 6th congress. In 1980, she said, the Philippine population was 48.1 million persons, up by 11.4 million persons or 31%, over the3l.7 million enumerated in 1970. While the rate of populated growth remains high, data indicate a decreasing post-World War II trend, from 3.06% in 1948-60 to 2.68% in 1975-80. The proportion of the population below 15 has dropped by 2 percentage points, while the number of persons in the working ages 15-64 has increased. In 1 of the 3 group sessions during the congress, the participants tried to define the Philippines' population distribution goals, the requirement of an urban-rural balance, and priority intervention areas. In that session 2 main papers were presented -- one on human settlements and urbanization and the other on macroeconomic policies and their spatial implications. In another sessionplanners and researchers examined the socioeconomic and demographic impact of development programs, specifically the impact of rural electrification on fertility change in Misamis Oriental, a province in Southern Philippines. In the

  14. Sources of Individual Differences in Children’s Understanding of Fractions

    OpenAIRE

    Vukovic, Rose K.; Fuchs, Lynn S.; Geary, David C.; Jordan, Nancy C.; Gersten, Russell; Siegler, Robert S.

    2014-01-01

    Longitudinal associations of domain-general and numerical competencies with individual differences in children’s understanding of fractions were investigated. Children (n = 163) were assessed at 6 years of age on domain-general (nonverbal reasoning, language, attentive behavior, executive control, visual-spatial memory) and numerical (number knowledge) competencies; at 7 years on whole-number arithmetic computations and number line estimation; and at 10 years on fraction concepts. Mediation a...

  15. Understanding and developing creativity: A practical approach

    Directory of Open Access Journals (Sweden)

    Donald J. Treffinger

    2008-06-01

    Full Text Available Critical thinking and creative thinking are proposed as determinants to cope with the constant change society, and basically children are experiencing nowadays. Moreover, tools for the development of critical and creative thinking are discussed, and the creative problem solving toolbox is presented, involving tools for generating options, as well as tools for focusing options. The importance of the tools as significant basis for the learning process, as well as for the management of changes in the creative problem solving solution, as well as its application from infancy to adulthood is discussed. Finally, recommendations about teaching and application of thinking tools are considered.

  16. Increasing Understanding and Social Acceptance of Individuals with Disabilities through Exploration of Comics Literature

    Science.gov (United States)

    McGrail, Ewa; Rieger, Alicja

    2016-01-01

    Research supports the inclusion of children with disabilities in general education classrooms as a way to boost academic and social development, not only for children with disabilities, but also for typically developing children. A wide variety of perspectives and abilities in the classroom builds empathy, understanding, and creativity--all…

  17. Understanding how individuals perceive carbon dioxide. Implications for acceptance of carbon dioxide capture and storage

    Energy Technology Data Exchange (ETDEWEB)

    Itaoka, K.; Saito, A. [Mizuho Information and Research Institute, Tokyo (Japan); Paukovic, M.; De Best-Waldhober, M. [ECN Policy Studies, Petten (Netherlands); Dowd, A.M.; Jeanneret, T.; Ashworth, P.; James, M. [The Global CCS Institute, Canberra (Australia)

    2012-06-15

    Carbon dioxide capture and storage (CCS) presents one potential technological solution for mitigating the atmospheric emission of carbon dioxide sources. However, CCS is a relatively new technology with associated uncertainties and perceived risks. For this reason, a growing body of research now focuses on public perceptions and potential for societal acceptance of CCS technology. Almost all explanations of CCS technology make reference to carbon dioxide, with an assumption that the general public understands CO2. It has become apparent that the general public’s knowledge and understanding of CO2’s properties influences how they engage with CO2 emitting industries and CCS technologies. However, surprisingly little research has investigated public perceptions, knowledge, and understanding of CO2. This investigation attempts to fill that gap. This report describes an investigation of how citizens of three countries (Japan, Australia, and the Netherlands) perceive CO2. Furthermore, it attempts to relate individual perceptions of CO2 to perceptions of CCS, and to determine how information provision about the underlying properties and characteristics of CO2 influences individual attitudes towards low carbon energy options, particularly CCS. In brief, the research had four ultimate aims. It aimed to: Explore the public’s knowledge and understanding of the properties of CO2; Examine the influence of that knowledge on their perceptions of CO2 and CCS; Investigate how information provision about the underlying properties and characteristics of CO2 influences individual attitudes towards CCS; and Identify if any differences between countries exist in relation to values and beliefs, knowledge of CO2’s properties, and CCS perceptions.

  18. Behaviour as a Lever of Ecological Transition? Understanding and Acting on Individual Behaviour and Collective Dynamics

    International Nuclear Information System (INIS)

    Martin, Solange; Gaspard, Albane

    2017-01-01

    Beyond broad policy declarations, the implementation of ecological transition - which consists mainly in curbing consumption of energy and raw materials in our societies - requires substantial behavioural change at the collective, but also, quite obviously, the individual level. Yet, though there is general consensus around the principle of embarking on the path to transition, things get more complicated when it comes to changing our practices and habits. Can we act on individual behaviour and collective dynamics in respect of this particular aim of ecological transition, and, if so, how are we to go about it? Solange Martin and Albane Gaspard have examined this question for the French Environment and Energy Management Agency (ADEME) and offer us the fruit of their labours here. They show, for example, how the social and human sciences help to understand behaviour both at the individual level and in its collective dimensions, and they outline different possible lines of action to modify it. But, given the entanglement between various levels, it is essential, if we are to act effectively on behaviour, to combine approaches, tools and actors, and to analyse and understand social practices thoroughly before implementing political projects or measures

  19. PREFACE: Scales of understanding in biological development Scales of understanding in biological development

    Science.gov (United States)

    Newman, Timothy

    2011-08-01

    The development of an adult organism from a fertilized egg remains one of the deep mysteries of biology. Great strides have been made in the past three decades, primarily through ever more sophisticated genetic analyses and the advent of live-cell imaging, yet the underlying principles governing development are elusive. Recently, a new generation of biological physicists has entered the field, attracted by the hallmarks of development— coordinated dynamics and pattern formation arising from cell-cell interactions—which reflect tantalizing analogs with many-body systems in condensed matter physics and related fields. There have been corresponding influxes of researchers from other quantitative disciplines. With new workers come new questions and foci at different scales in space, time and complexity. The reductionist philosophy of developmental genetics has become increasingly complemented by a search for effective mechanisms at higher scales, a strategy which has a proven track record of success in the study of complex systems in physics. Are there new and universal mechanisms of development, supra-genetic in nature, waiting to be discovered by focusing on higher scales, or is development fundamentally the intricately scripted unfolding of complex genetic instructions? In this special focus issue of Physical Biology, we present cutting-edge research into embryo development from a broad spectrum of groups representing cell and developmental biology, biological physics, bioengineering and biomathematics. We are provided with a sense of how this multidisciplinary community views the fundamental issue of scale in development and are given some excellent examples of how we can bridge these scales through interdisciplinary collaboration, in order to create new levels of understanding. We start with two reviews which will provide newcomers with a guide to some of the outstanding questions in the field. Winklbauer and Müller use the phenomenon of mesoderm spreading as

  20. The importance of understanding individual differences in Down syndrome [version 1; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Annette Karmiloff-Smith

    2016-03-01

    Full Text Available In this article, we first present a summary of the general assumptions about Down syndrome (DS still to be found in the literature. We go on to show how new research has modified these assumptions, pointing to a wide range of individual differences at every level of description. We argue that, in the context of significant increases in DS life expectancy, a focus on individual differences in trisomy 21 at all levels—genetic, cellular, neural, cognitive, behavioral, and environmental—constitutes one of the best approaches for understanding genotype/phenotype relations in DS and for exploring risk and protective factors for Alzheimer’s disease in this high-risk population.

  1. Auditory and Cognitive Factors Underlying Individual Differences in Aided Speech-Understanding among Older Adults

    Directory of Open Access Journals (Sweden)

    Larry E. Humes

    2013-10-01

    Full Text Available This study was designed to address individual differences in aided speech understanding among a relatively large group of older adults. The group of older adults consisted of 98 adults (50 female and 48 male ranging in age from 60 to 86 (mean = 69.2. Hearing loss was typical for this age group and about 90% had not worn hearing aids. All subjects completed a battery of tests, including cognitive (6 measures, psychophysical (17 measures, and speech-understanding (9 measures, as well as the Speech, Spatial and Qualities of Hearing (SSQ self-report scale. Most of the speech-understanding measures made use of competing speech and the non-speech psychophysical measures were designed to tap phenomena thought to be relevant for the perception of speech in competing speech (e.g., stream segregation, modulation-detection interference. All measures of speech understanding were administered with spectral shaping applied to the speech stimuli to fully restore audibility through at least 4000 Hz. The measures used were demonstrated to be reliable in older adults and, when compared to a reference group of 28 young normal-hearing adults, age-group differences were observed on many of the measures. Principal-components factor analysis was applied successfully to reduce the number of independent and dependent (speech understanding measures for a multiple-regression analysis. Doing so yielded one global cognitive-processing factor and five non-speech psychoacoustic factors (hearing loss, dichotic signal detection, multi-burst masking, stream segregation, and modulation detection as potential predictors. To this set of six potential predictor variables were added subject age, Environmental Sound Identification (ESI, and performance on the text-recognition-threshold (TRT task (a visual analog of interrupted speech recognition. These variables were used to successfully predict one global aided speech-understanding factor, accounting for about 60% of the variance.

  2. Change in higher education: understanding and responding to individual and organizational resistance.

    Science.gov (United States)

    Lane, India F

    2007-01-01

    In many fields, the ability of educators and practitioners to cope with rapid change is essential to sustained success. In veterinary medical education, as in other scientific disciplines, meaningful change is challenging to achieve and subject to resistance from many individual and organizational norms. Individual concerns often relate to fears of instability or uncertainty, loss of current status, or effects on individual time and workload. Sources of organizational resistance may include a conservative culture, fierce protection of current practices, and prevalence of disciplinary or territorial viewpoints. In academia, especially in scientific or medical fields, individuals appear to be strongly independent and conservative in nature, and generally skeptical of educational change. In this environment, a highly participatory process, with regular communication strategies and demonstrations or evidence that supports proposed changes, can be useful in facilitating change. An understanding of the nature of complex change, as well as of the reasons underlying resistance to change, and some methods to overcome these barriers are highly valuable tools for educational leaders.

  3. Toward understanding body image importance: individual differences in a Canadian sample of undergraduate students.

    Science.gov (United States)

    Siegling, Alexander B; Delaney, Mary E

    2013-01-01

    This study examined the relationships between body image importance (BII) and perfectionism and body satisfaction in a Canadian sample of undergraduate students. Specifically, perfectionism was conceptualized as a common cause of BII and body satisfaction. Furthermore, gender-schematic processing was examined as a moderator of sex differences in BII, which have been inconsistently found. As hypothesized, there was no significant partial correlation between BII and body satisfaction, controlling for perfectionism. Also, a significant Sex × Gender Schematicity interaction indicated that gender schematicity moderates sex differences in BII. Implications for understanding individual differences in, and elevated levels of BII are discussed.

  4. Identification of individuals' value and norms: One missing link to understanding new product success factors

    DEFF Research Database (Denmark)

    Harmsen, Hanne; Bove, Karsten

    and product and market characteristics to include aspects like individual and organisational skills, knowledge, values, and norms. We also argue that the focus on the mentioned aspects have limited the possibility of implementing the normative advice. Combining new product development literature with recent...

  5. Importance of Career Development for Individuals and Organizations

    Directory of Open Access Journals (Sweden)

    Mustafa Serbes

    2017-11-01

    Full Text Available Career development and planning is very significant to carry the organizations from current to the higher levels as well as professional and personal developments of the individuals. In terms of career, it can be said that the individuals and the organizations who invest in the career development can keep up with the others in the market. This paper tries to shed a light upon the importance of career development and shows basic traits of the career development.

  6. Understanding MBA Consumer Needs and the Development of Marketing Strategy

    Science.gov (United States)

    Dailey, Lynn; Anderson, Murphy; Ingenito, Cristina; Duffy, David; Krimm, Paul; Thomson, Scott

    2006-01-01

    The need to develop marketing strategies in higher education is evident. In order to develop effective strategies, marketers must understand the basic needs that their product fulfills. Exploratory research was utilized to identify and better understand the needs that motivate consumers to pursue an MBA degree. This paper emphasizes the importance…

  7. Understanding the development of temporary agency work in Europe

    NARCIS (Netherlands)

    B.A.S. Koene (Bas); J. Paauwe (Jaap); J.P.M. Groenewegen (John)

    2004-01-01

    textabstractThis article develops an explanatory framework for understanding the growth and development of temporary agency work (TAW) and the related industry. The analysis shows that explanations based on economic logic are helpful in understanding the choice of TAW in general. These explanations,

  8. Understanding customer need in the new product development context

    OpenAIRE

    Äärynen, Teemu

    2013-01-01

    This thesis project concentrates on how understanding customer need and customer orientation can be improved in new product development. Understanding customer need during new product development process is very important for product success. The case company has decided to undertake new product development using LEAN principles. This change creates a need to improve the new product development process. This thesis offers recommendations for the case company’s new product devel...

  9. Individual piglets' contribution to the development of tail biting

    NARCIS (Netherlands)

    Zonderland, J.J.; Kemp, B.; Bracke, M.B.M.; Hartog, den L.A.; Spoolder, H.A.M.

    2011-01-01

    Conflicting hypotheses exist about the contribution of individual pigs to the development of a tail-biting outbreak, but there is limited quantitative information to support or dismiss them. This study aims to quantify the development of tail-biting behaviour at pen and individual piglet level,

  10. Questioning in Distributed Product Development Teams: Supporting Shared Understanding

    DEFF Research Database (Denmark)

    Cash, Philip; Ahmed-Kristensen, Saeema

    2015-01-01

    Distributed teams are an increasingly common feature of New Product Development (NPD). Key to the success of these teams is the development of both short and longerterm shared understanding. Lack of shared understanding has been recognized as a significant challenge, particularly in the context...... globally distributed NPD activities. Poor shared understanding can ultimately result in delays and rework. One major antecedent of shared understanding development is question asking. This work uses a quasiexperimental study to test the impact of questioning support on different types of distributed teams......, both homogeneous and heterogeneous. This extends theoretical insight into the development of shared understanding and contributes one of few empirical studies directly comparing the response characteristics of different team types. From a managerial perspective this work has implications for how...

  11. Understanding predation risk and individual variation in risk avoidance for threatened boreal caribou.

    Science.gov (United States)

    Mumma, Matthew A; Gillingham, Michael P; Johnson, Chris J; Parker, Katherine L

    2017-12-01

    Predation risk is a driver of species' distributions. Animals can increase risk avoidance in response to fluctuations in predation risk, but questions remain regarding individual variability and the capacity to respond to changes in spatial risk across human-altered landscapes. In northeast British Columbia, Canada, boreal caribou populations declined as roads and seismic lines have increased, which are theorized to increase gray wolf predation. Our goal was to model risk and to evaluate individual variability and the development of risk perception by examining individual risk avoidance in response to reproductive status and age. We used locations from collared caribou and wolves to identify landscape features associated with the risk of a potential wolf-caribou encounter and risk of being killed given an encounter. We built resource selection functions to estimate individual responses to risk. We used general linear regressions to evaluate individual risk and linear feature avoidance as a function of age and reproductive status (calf or no calf). Linear features increased the risk of encounter. Older caribou and caribou with calves demonstrated stronger avoidance of the risk of encounter and roads, but weaker avoidance in late summer to the risk of being killed relative to younger and calf-less individuals. Mechanisms explaining the inverse relationships between the risk of encounter and risk of being killed are uncertain, but it is conceivable that caribou learn to avoid the risk of encounter and roads. Responses by females with vulnerable calves to the risk of encounter and risk of being killed might be explained by a trade-off between these two risk types and a prioritization on the risk of encounter. Despite the capacity to alter their responses to risk, the global decline in Rangifer populations (caribou and wild reindeer) suggests these behaviors are insufficient to mitigate the impacts of anthropogenic disturbances.

  12. Towards a comprehensive understanding of lead userness – the search for individual creativity

    DEFF Research Database (Denmark)

    Faullant, Rita; Schwarz, Erich; Krajger, Ines

    2012-01-01

    which is rooted in creativity psychology in order to provide a more comprehensive understanding of who leading‐edge users are. It will allow for a systematic investigation and detection of innovative users. We conducted an empirical study in the field of small kitchen appliances in co......‐operation with Philips Consumer Lifestyle, a field which lacks some of the typical characteristics that have been emphasized in markets traditionally studied in lead user research. With our research we show that (1) lead userness is fundamentally linked to individual creativity; (2) particularly creativity‐ and domain......‐relevant skills (cognitive style, product knowledge and use experience) are related to lead userness; (3) creativity‐relevant skills can be explained by personal characteristics, such as education, gender and openness to experience....

  13. Sources of Individual Differences in Children’s Understanding of Fractions

    Science.gov (United States)

    Vukovic, Rose K.; Fuchs, Lynn S.; Geary, David C.; Jordan, Nancy C.; Gersten, Russell; Siegler, Robert S.

    2014-01-01

    Longitudinal associations of domain-general and numerical competencies with individual differences in children’s understanding of fractions were investigated. Children (n = 163) were assessed at 6 years of age on domain-general (nonverbal reasoning, language, attentive behavior, executive control, visual-spatial memory) and numerical (number knowledge) competencies; at 7 years on whole-number arithmetic computations and number line estimation; and at 10 years on fraction concepts. Mediation analyses controlling for general mathematics ability and general academic ability revealed that numerical and mathematical competencies were direct predictors of fraction concepts whereas domain-general competencies supported the acquisition of fraction concepts via whole-number arithmetic computations or number line estimation. Results indicate multiple pathways to fraction competence. PMID:24433246

  14. Supporting the development of shared understanding in distributed design teams

    DEFF Research Database (Denmark)

    Cash, Philip; Dekoninck, Elies A; Ahmed-Kristensen, Saeema

    2017-01-01

    Distributed teams are an increasingly common feature of engineeringdesign work. One key factor in the success of these teams isthe development of short- and longer-term shared understanding.A lack of shared understanding has been recognized as a significantchallenge, particularly in the context o...

  15. Metamemory Development: Understanding the Role of Similarity in False Memories

    Science.gov (United States)

    Jaswal, Vikram K.; Dodson, Chad S.

    2009-01-01

    Research on the development of metamemory has focused primarily on children's understanding of the variables that influence how likely a person is to remember something. But metamemory also involves an understanding of why people occasionally misremember things. In this study, 5- and 6-year-olds (N = 38) were asked to decide whether another…

  16. Tool development to understand rural resource users' land use and ...

    African Journals Online (AJOL)

    Tool development to understand rural resource users' land use and impacts on land type changes in Madagascar. ... explore and understand decisions and management strategies. We finally report on first outcomes of the game including land use decisions, reaction to market fluctuation and landscape change. RÉSUMÉ

  17. All for one and one for all: understanding health professionals' experience in individual versus collaborative online learning.

    Science.gov (United States)

    MacNeill, Heather; Telner, Deanna; Sparaggis-Agaliotis, Alexandra; Hanna, Elizabeth

    2014-01-01

    Computer-supported collaborative learning (CSCL) may facilitate continuing interprofessional education while overcoming barriers of time and place for busy health care professionals. The purpose of this study was to understand the experiences, advantages, and challenges of group versus individual online learning. Fifteen multidisciplinary health professionals participated in a 12-week online course on either diabetes or traumatic brain injury. This consisted of background e-modules and a longitudinal build-a-case exercise, done either individually or as a group. Focus group sessions exploring participants' experiences after course completion and at 4 months were conducted, transcribed, and analyzed for recurring themes. Participant reflection homework and video-recorded group sessions were used for triangulation of results. Individual learners appreciated the flexibility and control, but experienced decreased motivation. Group learners appreciated the immediate feedback from their co-learners and felt social pressure to come to the weekly sessions prepared but expressed challenges in determining group goal-setting for the session. Both groups felt they learned about interprofessional roles; however, group learners described a richer learning experience and understanding of interprofessional roles through the online collaboration exercise. The intense resources necessary for interprofessional CSCL, including time, faculty development, and technological issues, are described. CSCL is a valuable educational strategy in online learning. While individual online learning may be better suited for short and simple educational interventions such as knowledge acquisition, CSCL seems to allow for richer and deeper learning in complex and interprofessional educational experiences. However, strategies, resources, and faculty development required to enhance CSCL need to be addressed carefully. © 2014 The Alliance for Continuing Education in the Health Professions, the Society

  18. Individual differences in the development of scientific thinking in kindergarten

    NARCIS (Netherlands)

    Graaf, J. van der; Segers, P.C.J.; Verhoeven, L.T.W.

    2018-01-01

    The present study examined the development of and individual variation in scientific thinking in kindergarten. We measured experimentation, evidence evaluation, and domain knowledge at two times in kindergarten (T1 and T2) in a sample of 100 five to six-year-olds. To explain individual differences,

  19. The Development of Emotion Recognition in Individuals with Autism

    Science.gov (United States)

    Rump, Keiran M.; Giovannelli, Joyce L.; Minshew, Nancy J.; Strauss, Mark S.

    2009-01-01

    Emotion recognition was investigated in typically developing individuals and individuals with autism. Experiment 1 tested children (5-7 years, n = 37) with brief video displays of facial expressions that varied in subtlety. Children with autism performed worse than the control children. In Experiment 2, 3 age groups (8-12 years, n = 49; 13-17…

  20. Agile Development and Software Architecture: Understanding Scale and Risk

    Science.gov (United States)

    2012-04-26

    Scrum Team A Scrum Team B Temporary sprint team 26 Agile Development and Software Architecture Robert L. Nord, SSTC, April 2012 © 2012 Carnegie...2012 Carnegie Mellon University Agile Development and Software Architecture: Understanding Scale and Risk Software Engineering Institute Carnegie... Agile Development and Software Architecture Robert L. Nord, SSTC, April 2012 © 2012 Carnegie Mellon University The challenge -1 Tradeoffs and their

  1. Supporting Parents with Two Essential Understandings: Attachment and Brain Development.

    Science.gov (United States)

    Berger, Eugenia Hepworth

    1999-01-01

    Readiness to learn is a constant state. Two critical aspects of early childhood provide parents sufficient understanding of their child's development: attachment and brain development. Children develop attachments to caregivers but need consistent parental care and love. Human brains continue to quickly grow during the first two years of life.…

  2. Redefining Individual Growth and Development Indicators: Oral Language

    Science.gov (United States)

    Bradfield, Tracy A.; Besner, Amanda C.; Wackerle-Hollman, Alisha K.; Albano, Anthony D.; Rodriguez, Michael C.; McConnell, Scott R.

    2014-01-01

    Language skills developed during preschool contribute strongly to later reading and academic achievement. Effective preschool assessment and intervention should focus on core components of language development, specifically oral language skills. The Early Language and Literacy Individual Growth and Development Indicators (IGDIs) are a set of…

  3. The Development of Mature Capabilities for Understanding and Valuing Technology through School Project Work.

    Science.gov (United States)

    Schallies, Michael; Wellensiek, Anneliese; Lembens, Anja

    This paper describes a German project that developed students' capabilities for understanding and valuing biotechnology and genetic engineering, focusing on practical fieldwork with schools by an interdisciplinary team. The paper identifies the characteristics of individual and structural preconditions and their development during active project…

  4. Children's understanding of area concepts: development, curriculum and educational achievement.

    Science.gov (United States)

    Bond, Trevor G; Parkinson, Kellie

    2010-01-01

    As one part of a series of studies undertaken to investigate the contribution of developmental attributes of learners to school learning, a representative sample of forty-two students (age from 5 years and 3 months to 13 years and 1 month) was randomly selected from a total student population of 142 students at a small private primary school in northern Australia. Those children's understandings of area concepts taught during the primary school years were assessed by their performance in two testing situations. The first consisted of a written classroom test of ability to solve area problems with items drawn directly from school texts, school examinations and other relevant curriculum documents. The second, which focused more directly on each child's cognitive development, was an individual interview for each child in which four "area" tasks such as the Meadows and Farmhouse Experiment taken from Chapter 11 of The Child's Conception of Geometry (Piaget, Inhelder and Szeminska, 1960, pp. 261-301) were administered. Analysis using the Rasch Partial Credit Model provided a finely detailed quantitative description of the developmental and learning progressions revealed in the data. It is evident that the school mathematics curriculum does not satisfactorily match the learner's developmental sequence at some key points. Moreover, the children's ability to conserve area on the Piagetian tasks, rather than other learner characteristics, such as age and school grade seems to be a precursor for complete success on the mathematical test of area. The discussion focuses on the assessment of developmental (and other) characteristics of school-aged learners and suggests how curriculum and school organization might better capitalize on such information in the design and sequencing of learning experiences for school children. Some features unique to the Rasch family of measurement models are held to have special significance in elucidating the development/attainment nexus.

  5. PEDAGOGICAL TECHNIQUES TO DISCLOSE AND DEVELOP INDIVIDUAL TOLERANCE

    OpenAIRE

    ABIDOVA ZIYODA ASKAROVNA

    2016-01-01

    This article describes pedagogical techniques stimulating individual tolerance disclosure and development. Author distinguishes deductive techniques creating conditions for tolerance disclosure and inductive techniques forming tolerance as well as describes results of conducted research demonstrating the role of didactic techniques in tolerance developing among students.

  6. Understanding and Managing Process Interaction in IS Development Projects

    DEFF Research Database (Denmark)

    Bygstad, Bendik; Nielsen, Peter Axel

    2012-01-01

    Software-based information systems must be developed and implemented as a part of business change. This is a major challenge, since business change and the development of software-based information systems usually are performed in separate processes. Thus, there is a need to understand and manage...... critical events in the case, what led to the events, and what the consequences are. We discuss the implications for information systems research and in particular we discuss the contribution to project management of iterative and incremental software development.......Software-based information systems must be developed and implemented as a part of business change. This is a major challenge, since business change and the development of software-based information systems usually are performed in separate processes. Thus, there is a need to understand and manage...

  7. Understanding and Managing Process Interaction in IS Development Projects

    DEFF Research Database (Denmark)

    Bygstad, Bendik; Nielsen, Peter Axel

    2005-01-01

    Increasingly, information systems must be developed and implemented as a part of business change. This is a challenge for the IS project manager, since business change and information systems development usually are performed as separate processes. Thus, there is a need to understand and manage......-technical innovation in a situation where the organisational change process and the IS development process are parallel but incongruent. We also argue that iterative software engineering frameworks are well structured to support process interaction. Finally, we advocate that the IS project manager needs to manage...... the relationship between these two kinds of processes. To understand the interaction between information systems development and planned organisational change we introduce the concept of process interaction. We draw on a longitudinal case study of an IS development project that used an iterative and incremental...

  8. Developments in the scientific and clinical understanding of fibromyalgia.

    Science.gov (United States)

    Buskila, Dan

    2009-01-01

    Our understanding of fibromyalgia (FM) has made significant advances over the past decade. The current concept views FM as the result of central nervous system malfunction resulting in amplification of pain transmission and interpretation. Research done over the past years has demonstrated a role for polymorphisms of genes in the serotoninergic, dopaminergic and catecholaminergic systems in the etiopathogenesis of FM. Various external stimuli such as infection, trauma and stress may contribute to the development of the syndrome. The management of FM requires an integrated approach combining pharmacological and nonpharmacological modalities. The recent Food and Drugs Administration approval of pregabalin, duloxetine and milnacipran as medications for FM may herald a new era for the development of medications with higher specificity and efficacy for the condition. As our understanding of the biological basis and the genetic underpinning of FM increases, we hope to gain a better understanding of the true nature of the disorder, to better classify patients and to attain more rational therapeutic modalities.

  9. Public Understanding of Sustainable Development: Some Implications for Education

    Science.gov (United States)

    Scott, William

    2015-01-01

    A number of recent surveys of public opinion claim that there is now widespread acceptance of the need for sustainable development, and that the general public, through its social and consumer activity is already successfully engaged. However, in all this, the focus has primarily been on individual and family behaviours such as recycling and…

  10. Towards a Shared Understanding of Skill Shortages: Differing Perceptions of Training and Development Needs

    Science.gov (United States)

    Skinner, Denise; Saunders, Mark N. K.; Beresford, Richard

    2004-01-01

    The question of how to develop human capabilities to meet current and future needs of organisations has become an important issue at national, organisational and individual levels. An essential ingredient is shared understanding of the skills and competences deemed necessary and/or desirable for current and future performance. Current indications…

  11. Supporting Staff to Develop a Shared Understanding of Science Assessment

    Science.gov (United States)

    Sampey, Carol

    2018-01-01

    Assessment is not something that stands alone and teachers need support to develop their understanding of both assessment practices and the subject being assessed. Teachers at Shaw Primary School were fortunate to take part in the Teacher Assessment in Primary Science (TAPS) project and, in this article, the outlines how science and assessment can…

  12. Mapping What Young Students Understand and Value Regarding Sustainable Development

    Science.gov (United States)

    Manni, Annika; Sporre, Karin; Ottander, Christina

    2013-01-01

    This paper presents the results of a study carried out to investigate how 10-12 year old Swedish students understand and value the issue of sustainable development. The responses from open-ended questions in a questionnaire have been analyzed through a content analysis based on a phenomenographic approach. The results show that there are…

  13. Understanding road users’ expectations : an essential step for ADAS development.

    NARCIS (Netherlands)

    Houtenbos, M. Jagtman, H.M. Hagenzieker, M.P. Wieringa, P.A. & Hale, A.R.

    2006-01-01

    This article indicates the need for understanding road users’ expectations when developing Advanced Driver Assistance Systems (ADAS). Nowadays, technology allows more and more opportunities to provide road users with all sorts of information or even actively support aspects of the driving task.

  14. Chemical Reactions: What Understanding Do Students with Blindness Develop?

    Science.gov (United States)

    Lewis, Amy L. Micklos; Bodner, George M.

    2013-01-01

    This study examined the understanding of chemical equations developed by three students with blindness who were enrolled in the same secondary-school chemistry class. The students were interviewed while interpreting and balancing chemical equations. During the course of these interviews, the students produced diagrams using Braille symbols that…

  15. Developing Primary School Children's Understanding of Energy Waste.

    Science.gov (United States)

    Kruger, Colin; Summers, Mike

    2000-01-01

    Studies 34 elementary school children's understanding of five aspects of energy waste and the ways in which these conceptions develop following teaching. Concludes that the children had good prior awareness of some behaviors that save energy, but their reasons for thinking this were based largely on everyday intuitive ideas that involved…

  16. Fraction Development in Children: Importance of Building Numerical Magnitude Understanding

    Science.gov (United States)

    Jordan, Nancy C.; Carrique, Jessica; Hansen, Nicole; Resnick, Ilyse

    2016-01-01

    This chapter situates fraction learning within the integrated theory of numerical development. We argue that the understanding of numerical magnitudes for whole numbers as well as for fractions is critical to fraction learning in particular and mathematics achievement more generally. Results from the Delaware Longitudinal Study, which examined…

  17. Young children's understanding of stages of human development

    OpenAIRE

    濱田, 祥子; 杉村, 伸一郎

    2010-01-01

    The self-concept is composed through the interaction with others (Mead,1934). As selfconceptual study in early childhood, most targets the same age others. However, it is thought that the existence of the others at other stages of development brings the influence to the self-concept if the self-concept is composed by the interaction with others. The present study aimed to search for children's understanding of stages of human development and children's self-concept by the comparisons between ...

  18. Communities of Practice : Finally a link between individual and organizational learning in management development programs

    NARCIS (Netherlands)

    Jürg Thölke; Donald Ropes

    2010-01-01

    This paper is about helping human resource development professionals to understand how community of practice theory can inform the design of learning-based programs in order to link individual and organizational learning better. Learning is often considered a major contributor to the success or

  19. Communities of practice : Finally a link between individual and organizational learning in management development programs

    NARCIS (Netherlands)

    Ropes, D.C.; Thölke, J.M.

    2010-01-01

    This paper is about helping human resource development professionals to understand how community of practice theory can inform the design of learning-based programs in order to link individual and organizational learning better. Learning is often considered a major contributor to the success or

  20. The Interplay of Individual Differences and Context of Learning in Behavioral and Neurocognitive Second Language Development

    Science.gov (United States)

    Faretta-Stutenberg, Mandy; Morgan-Short, Kara

    2018-01-01

    In order to understand variability in second language (L2) acquisition, this study addressed how individual differences in cognitive abilities may contribute to development for learners in different contexts. Specifically, we report the results of two short-term longitudinal studies aimed at examining the role of cognitive abilities in accounting…

  1. Growth and Development of Individualism and Universalism in ...

    African Journals Online (AJOL)

    Nekky Umera

    Whitman's poetry is filled with the ideas of the development of individualism and universalism as an integral phase of human life. Like all poets, he presents 'man' as curious, inquiring, and ... means that adolescence is a life stage where romanticism and idealism are confusingly mixed. In Section 6 of Song of Myself we ...

  2. LENDING PROJECT IMPACT ON AGRICULTURAL INDIVIDUAL SECTOR DEVELOPMENT IN MOLDOVA

    Directory of Open Access Journals (Sweden)

    Aurelia LITVIN

    2014-04-01

    Full Text Available Economic development within rural areas of the Republic of Moldova is affected by multiple issues which cross the agricultural individual sector development. One of the main factors that would influence positively the development of agriculture is investment. Investment plays an important role on the country's economy, representing the material support of its economic and social development. It ensures the permanent capital increase, advances the technical and economic efficiency of existing ones and creates new places of employment. In this context, investment is the decisive element of economic growth, of the intensive, qualitative and effective factors promotion.

  3. Use of proteomics to understand seed development in rice.

    Science.gov (United States)

    Deng, Zhu Yun; Gong, Chun Yan; Wang, Tai

    2013-06-01

    Rice is an important cereal crop and has become a model monocot for research into crop biology. Rice seeds currently feed more than half of the world's population and the demand for rice seeds is rapidly increasing because of the fast-growing world population. However, the molecular mechanisms underlying rice seed development is incompletely understood. Genetic and molecular studies have developed our understanding of substantial proteins related to rice seed development. Recent advancements in proteomics have revolutionized the research on seed development at the single gene or protein level. Proteomic studies in rice seeds have provided the molecular explanation for cellular and metabolic events as well as environmental stress responses that occur during embryo and endosperm development. They have also led to the new identification of a large number of proteins associated with regulating seed development such as those involved in stress tolerance and RNA metabolism. In the future, proteomics, combined with genetic, cytological, and molecular tools, will help to elucidate the molecular pathways underlying seed development control and help in the development of valuable and potential strategies for improving yield, quality, and stress tolerance in rice and other cereals. Here, we reviewed recent progress in understanding the mechanisms of seed development in rice with the use of proteomics. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  4. Understanding soaring bird migration through interactions and decisions at the individual level.

    Science.gov (United States)

    van Loon, E E; Shamoun-Baranes, J; Bouten, W; Davis, S L

    2011-02-07

    Many soaring bird species migrate southwards in autumn from their breeding grounds in Europe and Central Asia towards their wintering grounds. Our knowledge about interactions between migrating birds, thermal selection during migration and mechanisms that lead to flocking or convergent travel networks is still very limited. To start investigating these aspects we developed an individual-based simulation model that describes the local interactions between birds and their environment during their migratory flight, leading to emergent patterns at larger scales. The aim of our model is to identify likely decision rules with respect to thermal selection and navigation. After explaining the model, it is applied to analyse the migration of white storks (Ciconia ciconia) over part of its migration domain. A model base-run is accompanied by a sensitivity analysis. It appears that social interactions lead to the use of fewer thermals and slight increases in distance travelled. Possibilities for different model extensions and further model application are discussed. Copyright © 2010 Elsevier Ltd. All rights reserved.

  5. Understanding Discrepancy in Perceptions of Values: Individuals with Mild to Moderate Dementia and Their Family Caregivers

    Science.gov (United States)

    Reamy, Allison M.; Kim, Kyungmin; Zarit, Steven H.; Whitlatch, Carol J.

    2011-01-01

    Purpose of the Study: We explore discrepancies in perceptions of values and care preferences between individuals with dementia (IWDs) and their family caregivers. Design and Methods: We interviewed 266 dyads consisting of an individual with mild to moderate dementia and his or her family caregiver to determine IWDs' beliefs for 5 values related to…

  6. [Educative game on drugs for blind individuals: development and assessment].

    Science.gov (United States)

    Mariano, Monaliza Ribeiro; Rebouças, Cristiana Brasil de Almeida; Pagliuca, Lorita Marlena Freitag

    2013-08-01

    Study aimed to develop and assess an educational game on psychoactive drugs accessible to blind individuals, conducted in three steps: development of the educative game, evaluation by three special education experts, and assessment by twelve blind individuals. As a result, a board game called Drugs: staying clean was developed. In the Alpha version, experts made suggestions regarding the game rules and instructions and the board base, including square texture, game pieces, and Braille writing. In Beta version, we proceeded to the assessment by the blind participants, who suggested changes in the square texture and the addition of Velcro-type material to fix the counters on the board. Then, the Gamma version was played by the last pairs of blind players and was considered by them to be adequate. In the evaluation of the experts, the game was appropriate, as it allowed access to information on psychoactive drugs in a ludic and playful manner.

  7. Narratives with Robots: The Impact of Interaction Context and Individual Differences on Story Recall and Emotional Understanding

    Directory of Open Access Journals (Sweden)

    Iolanda Leite

    2017-07-01

    Full Text Available Role-play scenarios have been considered a successful learning space for children to develop their social and emotional abilities. In this paper, we investigate whether socially assistive robots in role-playing settings are as effective with small groups of children as they are with a single child and whether individual factors such as gender, grade level (first vs. second, perception of the robots (peer vs. adult, and empathy level (low vs. high play a role in these two interaction contexts. We conducted a three-week repeated exposure experiment where 40 children interacted with socially assistive robotic characters that acted out interactive stories around words that contribute to expanding children’s emotional vocabulary. Our results showed that although participants who interacted alone with the robots recalled the stories better than participants in the group condition, no significant differences were found in children’s emotional interpretation of the narratives. With regard to individual differences, we found that a single child setting appeared more appropriate to first graders than a group setting, empathy level is an important predictor for emotional understanding of the narratives, and children’s performance varies depending on their perception of the robots (peer vs. adult in the two conditions.

  8. Children's developing understanding of what and how they learn.

    Science.gov (United States)

    Sobel, David M; Letourneau, Susan M

    2015-04-01

    What do children know about learning? Children between 4 and 10 years of age were asked what they thought the word learning meant and then engaged in a structured interview about what kinds of things they learned and how they learned those things. Most of the 4- and 5-year-olds' responses to these questions indicated a lack of awareness about the nature of learning or how learning occurs. In contrast, the 8- to 10-year-olds showed a strong understanding of learning as a process and could often generate explicit metacognitive responses indicating that they understood under what circumstances learning would occur. The 6- and 7-year-olds were in a transitional stage between these two levels of understanding. We discuss the implications of this development with children's theory-of-mind development more generally. Copyright © 2015 Elsevier Inc. All rights reserved.

  9. Neuroendocrinology of coping styles : towards understanding the biology of individual variation

    NARCIS (Netherlands)

    Koolhaas, J M; de Boer, Sietse; Coppens, C M; Buwalda, B

    Individual variation in behavior and physiology is a widespread and ecologically functional phenomenon in nature in virtually all vertebrate species. Due to domestication of laboratory animals, studies may suffer from a strong selection bias. This paper summarizes behavioral, neuroendocrine and

  10. Developing Scene Understanding Neural Software for Realistic Autonomous Outdoor Missions

    Science.gov (United States)

    2017-09-01

    frameworks Name Developer Language Computation Key reference Caffe Berkeley Vision and Learning Center C++, Python /Matlab CPU, GPU a Torch Collobert...environment for machine learning . Proc Advances in Neural Information Processing Systems; EPFL-CONF-192376; 2011. c Al-Rfou R et al. Theano: A Python ...13. SUPPLEMENTARY NOTES 14. ABSTRACT We present a deep learning neural network model software implementation for improving scene understanding

  11. Understanding the individual to implement the ecosystem approach to fisheries management

    Science.gov (United States)

    Ward, Taylor D.; Algera, Dirk A.; Gallagher, Austin J.; Hawkins, Emily; Horodysky, Andrij; Jørgensen, Christian; Killen, Shaun S.; McKenzie, David J.; Metcalfe, Julian D.; Peck, Myron A.; Vu, Maria; Cooke, Steven J.

    2016-01-01

    Ecosystem-based approaches to fisheries management (EAFMs) have emerged as requisite for sustainable use of fisheries resources. At the same time, however, there is a growing recognition of the degree of variation among individuals within a population, as well as the ecological consequences of this variation. Managing resources at an ecosystem level calls on practitioners to consider evolutionary processes, and ample evidence from the realm of fisheries science indicates that anthropogenic disturbance can drive changes in predominant character traits (e.g. size at maturity). Eco-evolutionary theory suggests that human-induced trait change and the modification of selective regimens might contribute to ecosystem dynamics at a similar magnitude to species extirpation, extinction and ecological dysfunction. Given the dynamic interaction between fisheries and target species via harvest and subsequent ecosystem consequences, we argue that individual diversity in genetic, physiological and behavioural traits are important considerations under EAFMs. Here, we examine the role of individual variation in a number of contexts relevant to fisheries management, including the potential ecological effects of rapid trait change. Using select examples, we highlight the extent of phenotypic diversity of individuals, as well as the ecological constraints on such diversity. We conclude that individual phenotypic diversity is a complex phenomenon that needs to be considered in EAFMs, with the ultimate realization that maintaining or increasing individual trait diversity may afford not only species, but also entire ecosystems, with enhanced resilience to environmental perturbations. Put simply, individuals are the foundation from which population- and ecosystem-level traits emerge and are therefore of central importance for the ecosystem-based approaches to fisheries management. PMID:27293757

  12. Diffusion tensor imaging for understanding brain development in early life.

    Science.gov (United States)

    Qiu, Anqi; Mori, Susumu; Miller, Michael I

    2015-01-03

    The human brain rapidly develops during the final weeks of gestation and in the first two years following birth. Diffusion tensor imaging (DTI) is a unique in vivo imaging technique that allows three-dimensional visualization of the white matter anatomy in the brain. It has been considered to be a valuable tool for studying brain development in early life. In this review, we first introduce the DTI technique. We then review DTI findings on white matter development at the fetal stage and in infancy as well as DTI applications for understanding neurocognitive development and brain abnormalities in preterm infants. Finally, we discuss limitations of DTI and potential valuable imaging techniques for studying white matter myelination.

  13. Shifting Stakes: Understanding the Dynamic Roles of Individuals and Organizations in Social Media Protests.

    Science.gov (United States)

    Spiro, Emma S; Monroy-Hernández, Andrés

    2016-01-01

    In this paper we examine two protests characterized by substantial social media presence and distributed participation frameworks via two core questions: what roles did organizations and individuals play, and how did participants' social interactions change over the course of the protests? To answer these questions, we analyzed a large Twitter activity dataset for the #YoSoy132 student uprising in Mexico and Brazil's "bus rebellion." Results indicate that individuals initially took prominence at the protests but faded in importance as the movements dwindled and organizations took over. Regarding the dynamics and structure of the interactions, we found that key time points with unique social structures often map to exogenous events such as coordinated protests in physical locations. Our results have important consequences for the visibility of such social movements and their ability to attract continued participation by individuals and organizations.

  14. Risk Perception for Developing Diabetes among Non-diabetic Individuals

    Directory of Open Access Journals (Sweden)

    Belkis Vicente Sánchez

    2016-06-01

    Full Text Available Background: the incidence and prevalence of type 2 diabetes mellitus have increased in recent decades and this trend is expected to continue. Objective: to determine the risk perception for developing type 2 diabetes among non-diabetic individuals. Methods: a cross-sectional study involving non-diabetic individuals in the catchment area of the doctor-and-nurse office No.15 of the Manuel Fajardo Polyclinic in Cienfuegos was conducted between May 2013 and June 2014. The universe consisted of 1145 people, and the sample included 323 individuals of different age groups selected by sex. The variables studied were: age, sex, body mass index, nutritional assessment, and having a perceived risk when they answered 70 % of questions correctly. The arithmetic mean, standard deviation, Chi-square test, and risk estimation were calculated with a 95 % confidence interval. Results: individuals aged 25 to 34 years and females predominated. Fifty nine point two percent of the study participants knew of their risk. Eighty one point one percent understood that diabetes is preventable and 93.5 % stated that it is their responsibility to prevent its development. Thirty five point two percent of women considered normal-weight/thin fully agreed on the importance of physical activity and diabetes prevention. Eighty point five percent of women and 78.5 % of men answered positively to the question about obesity and diabetes. Conclusions: study participants knew of their risk of developing type 2 diabetes, although a large number of them attributed all responsibility for prevention to the health personnel.

  15. Developing Engineering Students’ Understanding of Sustainability Using Project Based Learning

    Directory of Open Access Journals (Sweden)

    Margaret Jollands

    2013-11-01

    Full Text Available Project based learning (PjBL can be an effective approach to developing graduate attributes, but it depends on how it is implemented. Chemical Engineering of RMIT University has a stream of PjBL subjects from first to final year. The projects are incrementally more complex but have the same goal: to choose a best process design, using management decision making tools to justify their choices. The tools include GEMI Metrics NavigatorTM. This paper reports an evaluation of whether students’ understanding of sustainability is enhanced by undertaking multiple projects, as well as use of sophisticated analysis tools. Student learning outcomes from intermediate and final subjects were compared using ConceptMaps and a focus group. The students’ understanding of sustainability increased substantially from 2nd to final year, similar to results reported in European studies. The spread of results was broad, attributed to range of student ability and differences between student cohorts. Development of understanding of sustainability was attributed to undertaking multiple projects and use of spread-sheeting tools. Use of the GEMI tool was identified as facilitating application of sustainability principles to process design decisions. Concept maps are a useful way to evaluate innovations in teaching sustainable engineering.

  16. Understanding energy technology developments from an innovation system perspective

    Energy Technology Data Exchange (ETDEWEB)

    Borup, M.; Nygaard Madsen, A. [Risoe National Lab., DTU, Systems Analysis Dept., Roskilde (Denmark); Gregersen, Birgitte [Aalborg Univ., Department of Business Studies (Denmark)

    2007-05-15

    With the increased market-orientation and privatisation of the energy area, the perspective of innovation is becoming more and more relevant for understanding the dynamics of change and technology development in the area. A better understanding of the systemic and complex processes of innovation is needed. This paper presents an innovation systems analysis of new and emerging energy technologies in Denmark. The study focuses on five technology areas: bio fuels, hydrogen technology, wind energy, solar cells and energy-efficient end-use technologies. The main result of the analysis is that the technology areas are quite diverse in a number of innovation-relevant issues like actor set-up, institutional structure, maturity, and connections between market and non-market aspects. The paper constitutes background for discussing the framework conditions for transition to sustainable energy technologies and strengths and weaknesses of the innovation systems. (au)

  17. The communication of expectations and individual understanding: redundancy as reduction of uncertainty, and the processing of meaning

    NARCIS (Netherlands)

    Leydesdorff, L.; Johnson, M.; Ivanova, I.A.

    2014-01-01

    Purpose The purpose of this paper is to present the case for an analysis of communication at the supra-individual level as a means of rendering the understanding of learning and acting tractable. The paper introduces a method of analysis of redundancy to achieve this. Design/methodology/approach The

  18. The Individual-Practice Framework as a design tool to understand consumer behaviour

    NARCIS (Netherlands)

    Piscicelli, L.; Moreno, Mariale; Cooper, Tim; Fisher, Tom

    2016-01-01

    Design for behaviour change is a growing research field which aims at providing methods and tools to foster pro-environmental and pro-social action through the application of diverse theories, models and approaches from the social sciences. This chapter presents the Individual-Practice Framework,

  19. Understanding the Friendship Processes of Individuals with Asperger's Syndrome: A Phenomenological Study of Reflective College Experiences

    Science.gov (United States)

    Lee, Kammie Bohlken

    2010-01-01

    This phenomenological study shed light on the reflective college experiences of 11 individuals with Asperger's Syndrome and High Functioning Autism from a competence rather than a deficit model of disability (Biklen, 2005). Using Goleman's model of Social Intelligence (2006) as a theoretical framework, the cognitive, behavioral, and affective…

  20. Supporting Individuals with Autism Spectrum Disorder in Understanding and Coping with Complex Social Emotional Issues

    Science.gov (United States)

    Ahlers, Kaitlyn P.; Gabrielsen, Terisa P.; Lewis, Danielle; Brady, Anna M.; Litchford, April

    2017-01-01

    Core deficits in autism spectrum disorder (ASD) center around social communication and behavior. For those with ASD, these deficits complicate the task of learning how to cope with and manage complex social emotional issues. Although individuals with ASD may receive sufficient academic and basic behavioral support in school settings, supports for…

  1. The Four Personae of Racism: Educators' (Mis)Understanding of Individual vs. Systemic Racism

    Science.gov (United States)

    Young, Evelyn Y.

    2011-01-01

    This study used CRT to engage educators in critical discourse regarding the persistence of racism in urban schooling. A combined method of action research and critical case study was employed to raise a group of educators' race consciousness through antiracist training. Findings revealed conflicting views of racism as an individual pathology vs. a…

  2. Understanding technology adoption through individual and context characteristics: the case of HDTV

    NARCIS (Netherlands)

    Baaren, Eva; van de Wijngaert, Lidwien; Huizer, E.

    2011-01-01

    Technology adoption research has a tradition of using and improving Davis' (1989) “Technology Acceptance Model” (TAM) and extended versions of it. This article suggests a break with this tradition by showing that the TAM is limited in its understanding of technology adoption. Two alternative

  3. Development of Individualized Anti-Metastasis Strategies by Engineering Nanomedicines

    Science.gov (United States)

    He, Qianjun; Guo, Shengrong; Qian, Zhiyong; Chen, Xiaoyuan

    2015-01-01

    Metastasis is deadly and also tough to treat as it is much more complicated than the primary tumour. Anti-metastasis approaches available so far are far from being optimal. A variety of nanomedicine formulas provide a plethora of opportunities for developing new strategies and means for tackling metastasis. It should be noted that individualized anti-metastatic nanomedicines are different from common anti-cancer nanomedicines as they specifically target different populations of malignant cells. This review briefly introduces the features of the metastatic cascade, and proposes a series of nanomedicine-based anti-metastasis strategies aiming to block each metastatic step. Moreover, we also concisely introduce the advantages of several promising nanoparticle platforms and their potential for constructing state-of-the-art individualized anti-metastatic nanomedicines. PMID:26056688

  4. Developing and Understanding Intelligent Contexts for Playing and Learning

    DEFF Research Database (Denmark)

    Larsen, Lasse Juel; Helms, Niels Henrik

    2009-01-01

    of tangible learning media and develop didactic approaches for teachers in primary school and furthermore to use the user experiences in a structured process where children participated in the innovation process. This has raised a fundamental question: How should we understand the relationship between......This short paper outlines experiences and reflections on the research and development project “Octopus” in order to describe and illustrate how intelligent context facilitates and embody learning. The framework is a research and development project where we have tried to work with new kinds...... structure and process or in a more philosophical way: The relationship between epistemology and ontology in a designed set up for learning. This paper therefore aims at illustrating how and why the “Octopus” works and functions in the school setting and discussing the relations between distinctions...

  5. Developing and Understanding Intelligent Contexts for Playing and Learning

    DEFF Research Database (Denmark)

    Larsen, Lasse Juel; Helms, Niels Henrik

    of tangible learning media and develop didactic approaches for teachers in a primary school and furthermore to use the user experiences in a structured process where children participated in the innovation process. This has raised a fundamental question: How should we understand the relationship between......This paper outlines experiences and reflections on the research and development project “Octopus” in order to describe and illustrate how intelligent context facilitates and embody learning and play. The framework is a research and development project where we have tried to work we new kinds...... structure and process (or flow) or it could be formulated in a more philosophical way: The relationship between epistemology and ontology in a designed set up for learning i.e. a classroom setting with learning mediated through intelligent tangible learning media. The tangible learning media...

  6. High field superconductor development and understanding project, Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Larbalestier, David C.; Lee, Peter J.

    2009-07-15

    Over 25 years the Applied Superconductivity Center at the University of Wisconsin-Madison provided a vital technical resource to the High Energy Physics community covering development in superconducting strand for HEP accelerator magnet development. In particular the work of the group has been to develop the next generation of high field superconductors for high field application. Grad students Mike Naus, Chad Fischer, Arno Godeke and Matt Jewell improved our understanding of the microstructure and microchemistry of Nb3Sn and their impact on the physical and mechanical properties. The success of this work has led to the continued funding of this work at the ASC after it moved to the NHMFL and also to direct funding from BNL for some aspects of Nb3Sn cable evaluation.

  7. The recent development in understanding the periodic table of elements

    International Nuclear Information System (INIS)

    Niizeki, K.

    1986-01-01

    The recent development in understanding the periodic table of elements is reviewed. The author's concern is focussed on the effects which make different elements of a group of the periodic table to have different chemical properties, which result in that different members of a homologous series of compounds have different physical properties. The most important effect is due to the effective repulsion of the valence orbital of an atom from the core region by orthogonality with the core orbitals with the same azimuthal quantum number

  8. Developing An Analytic Approach to Understanding the Patient Care Experience

    Science.gov (United States)

    Springman, Mary Kate; Bermeo, Yalissa; Limper, Heather M

    2016-01-01

    The amount of data available to health-care institutions regarding the patient care experience has grown tremendously. Purposeful approaches to condensing, interpreting, and disseminating these data are becoming necessary to further understand how clinical and operational constructs relate to patient satisfaction with their care, identify areas for improvement, and accurately measure the impact of initiatives designed to improve the patient experience. We set out to develop an analytic reporting tool deeply rooted in the patient voice that would compile patient experience data obtained throughout the medical center. PMID:28725852

  9. Research and development into computer software to create story problems to promote the individual development of children (VII) : The Creation of an Interactive Learning Environment to Pose Multiplication or Division Word Problems for Promoting the Understanding of Problem Structures and their Practical Use

    OpenAIRE

    前田, 一誠; 平嶋, 宗; 小山, 正孝; 影山, 和也; 市村, 広樹

    2015-01-01

    Problem-posing is an effective learning strategy for the comprehension of problem structures. We designed and developed a learning environment for problem-posing and undertook practical experiments with first- and second-grade students at elementary school. The system included arithmetic word problems using one-step addition, subtraction, or multiplication. The results suggested that the learning environment is effective in helping students to comprehend these problem structures. This led us ...

  10. A territorial understanding of sustainability in public development

    International Nuclear Information System (INIS)

    Péti, Márton

    2012-01-01

    Sustainability theories in European Union (EU) development policies are facing significant challenges: it is difficult to transmit context-specific, publicly communicable messages; the recent development policies strengthen the concurrent development paradigm of economic growth and competitiveness; ‘climate change’ became a more popular environmental integration term than sustainability in the last few years. However, due to the recent crises of the economic growth, there is a great chance to reintroduce a sustainability-based development. A territorial/regional understanding of sustainability can also be an answer for the current challenges, a platform for refreshing the concept with relevant, specific messages that are close to the everyday life. This paper summarises the ‘territorial system’-based basic principles of territorial sustainability in a model called AUTHARSIIV (AUTonomy, HARmony, Solidarity, Innovation, Identity and Values). This is a supplementary sustainability content specified for the context of spatial/regional development or planning. The paper also examines the presence of ‘general and territorial sustainability’ in regional development programmes, and case studies on applying the territorial sustainability principles in planning, assessment, and implementation. According to the results, sustainability is rarely adapted to the conditions of a given sector or a region, and the territorial aspect of sustainability is underrepresented even in territorial programmes. Therefore, the paper proposes a new planning and assessment system that is based on a set of regionally legitimate sustainability values.

  11. A territorial understanding of sustainability in public development

    Energy Technology Data Exchange (ETDEWEB)

    Peti, Marton, E-mail: mpeti@vati.hu

    2012-01-15

    Sustainability theories in European Union (EU) development policies are facing significant challenges: it is difficult to transmit context-specific, publicly communicable messages; the recent development policies strengthen the concurrent development paradigm of economic growth and competitiveness; 'climate change' became a more popular environmental integration term than sustainability in the last few years. However, due to the recent crises of the economic growth, there is a great chance to reintroduce a sustainability-based development. A territorial/regional understanding of sustainability can also be an answer for the current challenges, a platform for refreshing the concept with relevant, specific messages that are close to the everyday life. This paper summarises the 'territorial system'-based basic principles of territorial sustainability in a model called AUTHARSIIV (AUTonomy, HARmony, Solidarity, Innovation, Identity and Values). This is a supplementary sustainability content specified for the context of spatial/regional development or planning. The paper also examines the presence of 'general and territorial sustainability' in regional development programmes, and case studies on applying the territorial sustainability principles in planning, assessment, and implementation. According to the results, sustainability is rarely adapted to the conditions of a given sector or a region, and the territorial aspect of sustainability is underrepresented even in territorial programmes. Therefore, the paper proposes a new planning and assessment system that is based on a set of regionally legitimate sustainability values.

  12. International education: developing site visit guidelines to enhance understanding.

    Science.gov (United States)

    DiFazio, Rachel; Boykova, Marina; Driever, Marie J

    2009-02-01

    International educational activities, whether organized as study tours or conferences, often include visits to various health care or educational facilities. These visits can provide a unique perspective on health care delivery, nursing education, and nursing practice. To maximize learning during such visits, a clear focus and guidelines are needed. The experience of conducting a conference in Russia is used as a basis for developing recommendations and creating guidelines for site visits that promote understanding of the nursing role and the health care system in another country. This article describes the process of developing educational objectives and guidelines for clinical and educational site visits. It is hoped the examples will be useful in planning site visits for other international educational activities.

  13. Understanding preferences for disclosure of individual biomarker results among participants in a longitudinal birth cohort.

    Science.gov (United States)

    Wilson, Stephen E; Baker, Erin R; Leonard, Anthony C; Eckman, Mark H; Lanphear, Bruce P

    2010-12-01

    To describe the preferences for disclosure of individual biomarker results among mothers participating in a longitudinal birth cohort. We surveyed 343 mothers that participated in the Health Outcomes and Measures of the Environment Study about their biomarker disclosure preferences. Participants were told that the study was measuring pesticide metabolites in their biological specimens, and that the health effects of these low levels of exposure are unknown. Participants were asked whether they wanted to receive their results and their child's results. In addition, they were asked about their preferred method (letter vs in person) and format (more complex vs less complex) for disclosure of results. Almost all of the study participants wanted to receive their individual results (340/343) as well as their child's results (342/343). However, preferences for receiving results differed by education level. Mothers with less than a college degree preferred in-person disclosure of results more often than mothers with some college education or a college degree (34.3% vs 17.4% vs 7.9%, pcollege education preferred a less complex disclosure format than mothers with some college education or a college degree (59.7% vs 79.1% vs 86.3%, p<0.0001). While almost all study participants preferred to receive results of their individual biomarker tests, level of education was a key factor in predicting preferences for disclosure of biomarker results. To ensure effective communication of this information, disclosure of biomarker results should be tailored to the education level of the study participants.

  14. Developing an agent-based model on how different individuals solve complex problems

    Directory of Open Access Journals (Sweden)

    Ipek Bozkurt

    2015-01-01

    Full Text Available Purpose: Research that focuses on the emotional, mental, behavioral and cognitive capabilities of individuals has been abundant within disciplines such as psychology, sociology, and anthropology, among others. However, when facing complex problems, a new perspective to understand individuals is necessary. The main purpose of this paper is to develop an agent-based model and simulation to gain understanding on the decision-making and problem-solving abilities of individuals. Design/Methodology/approach: The micro-level analysis modeling and simulation paradigm Agent-Based Modeling Through the use of Agent-Based Modeling, insight is gained on how different individuals with different profiles deal with complex problems. Using previous literature from different bodies of knowledge, established theories and certain assumptions as input parameters, a model is built and executed through a computer simulation. Findings: The results indicate that individuals with certain profiles have better capabilities to deal with complex problems. Moderate profiles could solve the entire complex problem, whereas profiles within extreme conditions could not. This indicates that having a strong predisposition is not the ideal way when approaching complex problems, and there should always be a component from the other perspective. The probability that an individual may use these capabilities provided by the opposite predisposition provides to be a useful option. Originality/value: The originality of the present research stems from how individuals are profiled, and the model and simulation that is built to understand how they solve complex problems. The development of the agent-based model adds value to the existing body of knowledge within both social sciences, and modeling and simulation.

  15. Coping Styles: A Better Understanding of Stress and Anxiety in Individuals With Autism Spectrum Conditions Through Sport and Exercise Models

    Directory of Open Access Journals (Sweden)

    Irina Roncaglia

    2014-10-01

    Full Text Available The aim of this paper is to present an understanding of the coping mechanisms and coping styles adopted by individuals on the Autism Spectrum Conditions (ASC by looking to draw parallels with sports performance psychology and how different sources of stress and anxiety can lead to the adoption of different coping styles. Firstly, an overview of current understanding of what constitute a stressor and how this can affect an individual is presented from sport and exercise psychology literature. Secondly, a model of coping styles is illustrated with the aim to shed light at how different perceptions of levels of stress and anxiety are managed both on an individual and group level. Thirdly, within the context of this understanding, some examples about how to support individuals on the ASC will be illustrated. Finally, implications for future research and reflection will be presented by highlighting the importance of teaching and learning coping and tolerance skills as part of a comprehensive and holistic psycho-educational program.

  16. Gender Identity and Adjustment: Understanding the Impact of Individual and Normative Differences in Sex Typing

    Science.gov (United States)

    Lurye, Leah E.; Zosuls, Kristina M.; Ruble, Diane N.

    2009-01-01

    The relationship among gender identity, sex typing, and adjustment has attracted the attention of social and developmental psychologists for many years. However, they have explored this issue with different assumptions and different approaches. Generally the approaches differ regarding whether sex typing is considered adaptive versus maladaptive, measured as an individual or normative difference, and whether gender identity is regarded as a unidimensional or multidimensional construct. In this chapter, we consider both perspectives and suggest that the developmental timing and degree of sex typing, as well as the multidimensionality of gender identity, be considered when examining their relationship to adjustment. PMID:18521861

  17. Gender identity and adjustment: understanding the impact of individual and normative differences in sex typing.

    Science.gov (United States)

    Lurye, Leah E; Zosuls, Kristina M; Ruble, Diane N

    2008-01-01

    The relationship among gender identity, sex typing, and adjustment has attracted the attention of social and developmental psychologists for many years. However, they have explored this issue with different assumptions and different approaches. Generally the approaches differ regarding whether sex typing is considered adaptive versus maladaptive, measured as an individual or normative difference, and whether gender identity is regarded as a unidimensional or multidimensional construct. In this chapter, we consider both perspectives and suggest that the developmental timing and degree of sex typing, as well as the multidimensionality of gender identity, be considered when examining their relationship to adjustment.

  18. Understanding watershed hydrogeochemistry: 1. Development of RT-Flux-PIHM

    Science.gov (United States)

    Bao, Chen; Li, Li; Shi, Yuning; Duffy, Christopher

    2017-03-01

    Model development in hydrology and geochemistry has been advancing separately with limited integration. We developed a watershed hydrogeochemical code RT-Flux-PIHM to understand complex interactions between hydrological processes (PIHM), land-surface processes (FLUX—Noah Land Surface Model), and multicomponent subsurface reactive transport (RT). The RT module simulates geochemical processes including aqueous complexation, surface complexation, mineral dissolution and precipitation, and cation exchange. The RT module is verified against the widely used reactive transport code CrunchFlow. The code uses semidiscrete finite volume method and irregular gridding and offers data harvesting capabilities from national databases. The application of RT-Flux-PIHM is demonstrated in the Susquehanna Shale Hills Critical Zone Observatory (SSHCZO). We aim to understand key processes that govern hydrogeochemical dynamics of the nonreactive chloride and reactive magnesium. Simulation results indicate that watershed characteristics, in particular topography, dictate the spatial distributions of water content and soil dissolution rates. Ion exchange provides buffering capacities and leads to a hysteresis loop of concentration and discharge relationship of magnesium, which differs from the open hysteresis of chloride. RT-Flux-PIHM offers physics-based modeling capabilities to integrate the vast amount of water and chemistry data that have now become available, to differentiate the relative importance of competing processes, and to test hypotheses at the interface of hydrology and geochemistry.

  19. What Is the Addiction World Like? Understanding the Lived Experience of the Individuals' Illicit Drug Addiction in Taiwan.

    Science.gov (United States)

    Hsieh, Mei-Hui; Tsai, Shu-Ling; Tsai, Chang-Hsiung; Hsu, Yu-Chien; Hsu, Min-Tao

    2017-01-01

    This study focuses on the participants' lived experience of addiction. The study presents a qualitative method. The use of the fieldwork-based participant observation and in-depth interviews guided the data collection and analysis. Three major themes of addiction emerge from the analysis: incorrigible conduct, inexcusable compromise, and inevitable corruption. This study provides a better understanding of what the world is like for people struggling with addiction and also enhances the healthcare professionals' knowledge of the individual's experience of addiction. This knowledge is essential for clinicians to understand this experience as a framework for planning and implementing appropriate treatment. © 2015 Wiley Periodicals, Inc.

  20. Understanding the mechanism of base development of hydrogen silsesquioxane

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jihoon; Chao, Weilun; Liang, Xiaogan; Griedel, Brian D.; Olynick, Deirdre L

    2009-01-09

    There have been numerous studies of electron beam exposed hydrogen silsesquioxane (HSQ) development conditions in order to improve the developer contrast. For TMAH based development, improvements were made by going to higher TMAH normalities and heating the developer. Yang and Berggren showed development of electron beam exposed (HSQ) by NaOH with added Na salts (various anions) significantly improves the contrast. Here, we study the contrast and etching rates of 100 keV exposed HSQ in NaOH in the presence of LiCl, NaCl, and KCl salts and use this as a segway to understand the mechanisms governing contrast during development HSQ development. The basic mechanism of development of HSQ can be understood by comparing to etching of quartz in basic solutions. Hydroxide ions act as nucleophiles which attack silicon. When a silicon-oxygen bond of the Si-O-Si matrix is broken, Si-O{sup -} and Si-OH are formed which can reversibly react to form the original structure. When a Si-H bond is broken via reaction with hydroxide, Si-O{sup -} and H{sub 2} gas are formed. Salts can change the etching rates as a function of dose in a non-linear fashion to increase etch contrast. Figs. 1, 2, and 3 show contrast curves for HSQ developed in 0.25 N sodium hydroxide and with the addition of NaCl, LiCl and KCl salts at several concentrations. NaCl addition resulted in the highest contrast. Contrast improves with additional salt concentration while sensitivity decreases. Interestingly enough, addition of salt decreases the removal of material of NaOH alone at higher doses while increasing the rate at lower concentrations. Addition of LiCl salts improves contrast over NaOH alone. Furthermore, the sensitivity at all doses increases as the LiCl concentration increases, a salting out effect. Similar to NaCl salt behavior, the addition of KCl salts, improves contrast at the expense of sensitivity. However, unlike NaCl, even at very high doses, KCl addition increases removal rate of HSQ. We

  1. Study of zircaloy corrosion to develop mechanistic understanding

    International Nuclear Information System (INIS)

    Ortner, S.; Swan, H.; Laferrere, A.; English, C.; Hyde, J.; Styman, P.; Jurkschat, K.; Hulme, H.; Pantelli, A.; Gass, M.; Allen, V.; Frankel, P.

    2015-01-01

    Predictions for the corrosion behaviour of Zircaloy cladding are based on empirical models. This results in significant uncertainties for forecasts beyond existing data e.g. for high burn-up, or when there has been a change in operating conditions. To allow for a more accurate prediction of corrosion behaviour a better understanding of the mechanisms involved is required. A program has been initiated with the aim of developing a detailed mechanistic understanding of out-of-pile Zircaloy corrosion behaviour. This paper reports the results of isothermal exposures of Zircaloy-4 to PWR water at 350 Celsius degrees. A variety of analytical techniques have been employed to analyse the corroded specimens, including scanning and transmission electron microscopy, atom probe tomography, micro-beam synchrotron X-ray diffraction and electron energy loss spectroscopy. When the results of these techniques are compared, it becomes evident that the periodic transition from slow to fast oxidation rates results from the accumulation of stress relief processes in the metal (particularly plastic deformation, but also oxygen and hydrogen dissolution); at the metal-oxide interface (decomposition of the flat interface into undulations); and in the oxide (cracking). These reduce the in-plane compressive stresses near the metal-oxide interface but ultimately balance them with in-plane tensile stresses which encourage through-thickness cracking, and the percolation of the environment to the metal-oxide interface. This is noticed only if allowance is made for out-of-plane stresses in the thin oxide. (authors)

  2. Developing Lesson Design to Help Students’ Triangle Conseptual Understanding

    Science.gov (United States)

    Prabawanto, S.; Mulyana, E.

    2017-09-01

    The research was aimed to develop a lesson design so that students’ triangle conceptual understanding could be achieved. The method that be used in this research was qualitative with applied didactical design research (DDR). The DDR consisted of three main stepts, namely prospective analysis, metapedadicdactic analysis, and retrospective analysis. From the three stepts above, it was gained the empirical lesson design of triangle topic. The reseach results are: (1) there were some learning obstacles of students deal with the triangle topic, namely ontogenical, epietimological, and didactical obstacles; (2) implementaion of the lesson was conducted under three main stepts, namely action, formulation, and validation. For answering weather the design can be applied to other group of students, it was recommended that it cound be investigated by doing advanced reseach.

  3. An integrative review: understanding driving retirement decisions for individuals living with a dementia.

    Science.gov (United States)

    Andrew, Catherine; Traynor, Victoria; Iverson, Don

    2015-12-01

    To synthesise primary research exploring decision making practices used to determine the time to retire from driving for individuals living with a dementia. Driving requires complex cognitive and physical skills potentially compromised due to the progressive nature of dementia. Whilst on-road assessments are considered reliable indicators of driving capacity by clinicians, drivers with dementia disagree. Integrative literature review informed by Whittemore & Knafl (2005). Electronic database search of Medline, CINAHL, Web of Science, Google Scholar 1997-2012; and incremental hand search. Primary studies published in peer reviewed journals were appraised against quality assessment criteria using CASP methodological assessment tools. A total of 43 studies were retained for synthesis. Key findings were abstracted and a themes matrix was generated to identify patterns of meaning. Six themes emerged: (i) dementia may compromise the complex task of driving; (ii) defining onset and severity of dementia is problematic; (iii) symptom progression impacts on driving skills; (iv) assessment of fitness to drive remains subjective; (v) some drivers are reluctant to accept negative assessment outcomes; and (vi) the search for effective strategies to enhance acceptance of driver retirement continues. This integrative literature review identified a large body of knowledge exploring the issues of driving cessation for drivers with dementia. However a challenge remains for practitioners, drivers and their family carers regarding how best to address this highly emotive issue. Findings could inform a structured approach to address this sensitive topic in a timely manner. © 2015 The Authors. Journal of Advanced Nursing published by John Wiley & Sons Ltd.

  4. Developing an understanding between people: the key to global health.

    Science.gov (United States)

    Serafin, Alina

    2010-05-01

    Global health and international health are prominent concepts within development issues today. Health is at the heart of many of the Millennium Development Goals, and the idea of a human right to health and health care has taken more hold in the forefronts of our minds. In acknowledgement of the globalised and interdependent society in which we live, this reflective piece uses personal experiences of anthropology and travel throughout the author's medical education to illustrate the pressing need for a better understanding between health workers and local populations. Experiences in Ecuador, Peru, India and Nepal, highlight the plurality of medicine. They show how medical education in the UK forms only one part of medical knowledge, and in particular how clinical practice requires the appreciation of a wider context. Within a multi-cultural society, it is essential that medical students learn new skills for the future. Teaching Anthropology and Sociology within the curriculum in the UK can educate students about how knowledge is created within a culture and to appreciate the diversity between cultures. Consideration of patients' backgrounds and beliefs allows health workers to develop relationships with the local population, which can be of invaluable use in making global health equality a reality. Copyright 2010 Elsevier Ltd. All rights reserved.

  5. Probabilistic Interval Forecasts: An Individual Differences Approach to Understanding Forecast Communication

    Directory of Open Access Journals (Sweden)

    Margaret A. Grounds

    2017-01-01

    Full Text Available Predictive interval forecasts, showing a range of values with specified probability, have the potential to improve decisions compared to point estimates. The research reported here demonstrates that this advantage extends from college undergraduates to a wide user group and does not depend on education. In two experiments, participants made decisions based on predictive intervals or point estimates and answered questions about them. In Experiment 1, they also completed numeracy and working memory span tests. Those using predictive intervals were better able to identify situations requiring precautionary action. Nonetheless, two errors were noted: (1 misinterpreting predictive intervals as diurnal fluctuation (deterministic construal errors and (2 judging the probability of events within and beyond the interval, when asked about them separately, as greater than 100%. These errors were only partially explained by WMS and numeracy. Importantly, omitting visualizations eliminated deterministic construal errors and overestimation of percent chance was not consistently related to decision quality. Thus, there may be important benefits to predictive interval forecasts that are not dependent on a full understanding of the theoretical principles underlying them or an advanced education, making them appropriate for a broad range of users with diverse backgrounds, weather concerns, and risk tolerances.

  6. DEVELOPING OF INDIVIDUAL INSTRUMENT PERFORMANCE ANXIETY SCALE: VALIDITY - RELIABILITY STUDY

    Directory of Open Access Journals (Sweden)

    Esra DALKIRAN

    2014-07-01

    Full Text Available The purpose of this study is to develop a scale unique to our culture, concerning  individual instrument performance anxiety of the students  who are getting instrument training  in the Department of Music Education. In the study, the descriptive research model is used and qualitative research techniques are utilized. The study population consists of the students attending the 23 universities which has Music Education Department. The sample of the study consists of 438 girls and 312 boys, totally 750 students  who are studying in the Department of Music Education of randomly selected 10 universities. As a result of the explanatory and confirmatory factor analyses that were performed, a one-dimensional structure consisting of 14 items was obtained. Also, t-scores and  the coefficient scores of total item correlation concerning the distinguishing power of the items, the difference in the scores of the set of lower and upper 27% was calculated, and it was observed that the items are distinguishing as a result of both analyses. Of the scale, Cronbach's alpha coefficient of internal consistency was calculated as .94, and test-retest reliability coefficient was calculated as .93. As a result, a valid and reliable assessment and evaluation instrument that measures the exam performance anxiety of the students studying in the Department of Music Education, has been developed.Extended AbstractsIntroductionAnxiety is a universal phenomenon which people experience once or a few times during lives. It was accepted as concern for the future or as an unpleasant emotional experience regarding probable hitches of the events (Di Tomasso & Gosch, 2002.In general, the occasions on which negative feelings are experienced cause anxiety to arise (Baltaş and Baltaş, 2000. People also feel anxious in dangerous situations. Anxiety may lead a person to be creative, while it may have hindering characteristics. Anxiety is that an individual considers him

  7. Understanding Alginate Gel Development for Bioclogging and Biogeophysical Experiments

    Science.gov (United States)

    Brown, I.; Atekwana, E. A.; Abdel Aal, G. Z.; Atekwana, E. A.; Sarkisova, S.; Patrauchan, M.

    2012-12-01

    Bioremediation strategies to mitigate the transport of heavy metals and radionuclides in subsurface sediments have largely targeted to increase the mobility and/or solubility of these compounds by the stimulation of biogeochemical activity of the metal- and sulfate-reducing bacteria. The latter secrete and/or release out diverse biochemical molecule including, first of all, organic acids and biopolymers such as alginic acid, proteins and DNA. Alginate gel is one of the major components determining the structure of biofilm which causes clogging in porous media. Biopolymers composing biofilm having, at least, two main functions: to be a scaffold for a microbial biofilm, and to regulate the exchange of metabolites and ions between an environment and bacterial cells. Additionally, the accumulation of biopolymers and a matured biofilm within porous media was shown to contribute to a detectable biogeophysical signal, spectral induced polarization (SIP), in particular. Our objective is to understand the role of different biofilm components on the SIP response as the latter has been proposed as a non-invasive tool to monitor biofilm development and rate of clogging in the subsurface. Understanding the process of alginate gel development may aid in the understanding of the fate and transport of mineralized heavy metals and radionuclides in contaminated soils. Here we describe the reciprocal relationship between environmental chemistry and alginate gel development. Commercial (Sigma) alginic acid (AA) was used as a substratum for the preparation of a model gel. AA was solubilized by adjusting solutions with pH up to 4 with 0.1 NaOH. Both Ca(OH)2 or CaCl2 were used to initiate the gelation of alginate. pH, fluid conductivity, soluble Ca2+ concentration, and a yield of gelated alginate were monitored in both liquid and porous media after the interaction of calcium compounds with alginate. This study confirms the critical role of Ca2+ for alginate gelation, biofilm development

  8. UNDERSTANDING THE NEUROINFLAMMATORY RESPONSE FOLLOWING CONCUSSION TO DEVELOP TREATMENT STRATEGIES

    Directory of Open Access Journals (Sweden)

    Zachary Robert Patterson

    2012-12-01

    Full Text Available Mild traumatic brain injuries (mTBI have been associated with long-term cognitive deficits relating to trauma-induced neurodegeneration. These long-term deficits include impaired memory and attention, changes in executive function, emotional instability and sensorimotor deficits. Furthermore, individuals with concussions show a high co-morbidity with a host of psychiatric illnesses (e.g. depression, anxiety, addiction and dementia. The neurological damage seen in mTBI patients is the result of the direct impact and mechanical injury, followed by a delayed neuroimmune response that can last hours, days and even months after the injury. As part of the neuroimmune response, a cascade of pro- and anti-inflammatory cytokines are released and can be detected at the site of injury as well as subcortical, and often contralateral, regions. It has been suggested that the delayed neuroinflammatory response to concussions is more damaging then the initial impact itself. However, evidence exists for favourable consequences of cytokine production following traumatic brain injuries as well. In some cases, treatments that reduce the inflammatory response will also hinder the brain's intrinsic repair mechanisms. At present, there is no evidence-based pharmacological treatment for concussions in humans. The ability to treat concussions with drug therapy requires an in-depth understanding of the pathophysiological and neuroinflammatory changes that accompany concussive injuries. The use of neurotrophic factors (e.g. nerve growth factor and anti-inflammatory agents as an adjunct for the management of post-concussion symptomology will be explored in this review.

  9. Beyond Sally's missing marble: further development in children's understanding of mind and emotion in middle childhood.

    Science.gov (United States)

    Lagattuta, Kristin Hansen; Kramer, Hannah J; Kennedy, Katie; Hjortsvang, Karen; Goldfarb, Deborah; Tashjian, Sarah

    2015-01-01

    Research on the development of theory of mind (ToM), the understanding of people in relation to mental states and emotions, has been a vibrant area of cognitive development research. Because the dominant focus has been addressing when children acquire a ToM, researchers have concentrated their efforts on studying the emergence of psychological understanding during infancy and early childhood. Here, the benchmark test has been the false-belief task, the awareness that the mind can misrepresent reality. While understanding false belief is a critical milestone achieved by the age of 4 or 5, children make further advances in their knowledge about mental states and emotions during middle childhood and beyond. Thus, a comprehensive understanding of children's sociocognitive abilities in older age groups is necessary to understand more fully the course of ToM development. The aim of this review is to outline continued development in ToM during middle childhood. In particular, we focus on children's understanding of interpretation-that different minds can construct different interpretations of the same reality. Additionally, we consider children's growing understanding of how mental states (thoughts, emotions, decisions) derive from personal experiences, cohere across time, and interconnect (e.g., thoughts shape emotions). We close with a discussion of the surprising paucity of studies investigating individual differences in ToM beyond age 6. Our hope is that this chapter will invigorate empirical interest in moving the pendulum toward the opposite research direction-toward exploring strengths, limitations, variability, and persistent errors in developing theories of mind across the life span. © 2015 Elsevier Inc. All rights reserved.

  10. Personal construct psychology: a theory to help understand professional development, a philosophy to support it.

    Science.gov (United States)

    Brocklehurst, Paul R

    2010-10-01

    The aim of this paper is to introduce the reader to personal construct psychology as a theory to help understand the process of change in facilitative and mentoring relationships. Continuing professional development is critical if practitioners are to keep up to date with new ideas, techniques, and materials. However, is it important not only to consider what is learnt, it is also important to understand the how of learning in order to develop an approach that leads to lifelong learning. Mentoring, coaching, and appraisal are all facilitative processes that aim to encourage professionals to engage with their own development. This leads to differing degrees of both behavioural and attitudinal change. As a result, it is useful to have a theory that can help an individual to understand these changes and to identify any difficulties that are associated with them. Personal construct psychology has long been recognised as a potential framework for personal development. It has been used extensively in a broad range of domains, including clinical and educational psychology, management, and psychotherapy. Personal construct psychology is a useful theory for understanding the facilitative process because it enables the facilitator to form a conceptual framework to comprehend behavioural and attitudinal change. Its underlying philosophical approach also supports lifelong learning, given its emphasis on an enquiring mind and reflection, both of which are key to continuing professional development.

  11. Development of a scale to measure individuals' ratings of peace.

    Science.gov (United States)

    Zucker, Howard; Ahn, Roy; Sinclair, Samuel Justin; Blais, Mark; Nelson, Brett D; Burke, Thomas F

    2014-01-01

    The evolving concept of peace-building and the interplay between peace and health is examined in many venues, including at the World Health Assembly. However, without a metric to determine effectiveness of intervention programs all efforts are prone to subjective assessment. This paper develops a psychometric index that lays the foundation for measuring community peace stemming from intervention programs. After developing a working definition of 'peace' and delineating a Peace Evaluation Across Cultures and Environments (PEACE) scale with seven constructs comprised of 71 items, a beta version of the index was pilot-tested. Two hundred and fifty subjects in three sites in the U.S. were studied using a five-point Likert scale to evaluate the psychometric functioning of the PEACE scale. Known groups validation was performed using the SOS-10. In addition, test-retest reliability was performed on 20 subjects. The preliminary data demonstrated that the scale has acceptable psychometric properties for measuring an individual's level of peacefulness. The study also provides reliability and validity data for the scale. The data demonstrated internal consistency, correlation between data and psychological well-being, and test-retest reliability. The PEACE scale may serve as a novel assessment tool in the health sector and be valuable in monitoring and evaluating the peace-building impact of health initiatives in conflict-affected regions.

  12. Individual Stochastic Screening for the Development of Computer Graphics

    Directory of Open Access Journals (Sweden)

    Maja Turčić¹*

    2012-12-01

    Full Text Available With the emergence of new tools and media, art and design have developed into digital computer-generated works. This article presents a sequence of creating art graphics because their original authors have not published the procedures. The goal is to discover the mathematics of an image and the programming libretto with the purpose of organizing a structural base of computer graphics. We will elaborate the procedures used to produce graphics known throughout the history of art, but that are nowadays also found in design and security graphics. The results are closely related graphics obtained by changing parameters that initiate them. The aim is to control the graphics, i.e. to use controlled stochastic to achieve desired solutions. Since the artists from the past have never published the procedures of screening methods, their ideas have remained “only” the works of art. In this article we will present the development of the algorithm that, more or less successfully, simulates those screening solutions. It has been proven that mathematically defined graphical elements serve as screening elements. New technological and mathematical solutions are introduced in the reproduction with individual screening elements to be used in printing.

  13. The Contribution of Cognitive Factors to Individual Differences in Understanding Noise-Vocoded Speech in Young and Older Adults

    Directory of Open Access Journals (Sweden)

    Stephanie Rosemann

    2017-06-01

    Full Text Available Noise-vocoded speech is commonly used to simulate the sensation after cochlear implantation as it consists of spectrally degraded speech. High individual variability exists in learning to understand both noise-vocoded speech and speech perceived through a cochlear implant (CI. This variability is partly ascribed to differing cognitive abilities like working memory, verbal skills or attention. Although clinically highly relevant, up to now, no consensus has been achieved about which cognitive factors exactly predict the intelligibility of speech in noise-vocoded situations in healthy subjects or in patients after cochlear implantation. We aimed to establish a test battery that can be used to predict speech understanding in patients prior to receiving a CI. Young and old healthy listeners completed a noise-vocoded speech test in addition to cognitive tests tapping on verbal memory, working memory, lexicon and retrieval skills as well as cognitive flexibility and attention. Partial-least-squares analysis revealed that six variables were important to significantly predict vocoded-speech performance. These were the ability to perceive visually degraded speech tested by the Text Reception Threshold, vocabulary size assessed with the Multiple Choice Word Test, working memory gauged with the Operation Span Test, verbal learning and recall of the Verbal Learning and Retention Test and task switching abilities tested by the Comprehensive Trail-Making Test. Thus, these cognitive abilities explain individual differences in noise-vocoded speech understanding and should be considered when aiming to predict hearing-aid outcome.

  14. Developing Primary School Children's Understanding of Energy Waste

    Science.gov (United States)

    Kruger, Colin; Summers, Mike

    2000-01-01

    This was an interview study of 34 primary school children's understanding of five aspects of energy waste, and the ways in which these conceptions develop following teaching. The aspects covered were: (i) saving energy by `using less'; (ii) saving energy by using `just enough'; (iii) energy waste through unintended transfers; (iv) energy waste in a household device; and (v) the meaning of the term `efficiency'. It was found that this group of primary school children had good prior awareness of some behaviours which save (or conserve) energy, but their reasons for thinking this were based largely on intuitive `everyday' ideas which involved human-centred notions of energy in the particular contexts presented or the movement of `heat' or `cold'. Notions of waste due to unintended outcomes were seen in only a few pupils initially but after teaching became far more prevalent. The study showed that basic ideas about energy waste which underpin energy conservation (using less energy) and the critically important scientific concept of efficiency were made accessible to an `average' group of primary school children. Moreover, this was done by ordinary practitioners who are not specialist teachers of science but who have had their subject and teaching knowledge enhanced by appropriate training.

  15. DEVELOPMENT OF INDIVIDUAL TREE GROWTH MODELS BASED ON DIFFERENTIAL EQUATIONS

    Directory of Open Access Journals (Sweden)

    Breno Rodrigues Mendes

    2006-09-01

    Full Text Available This study generate individual tree non-linear models from differential equation and evaluated the adjustment quality to express the basal area growth. The data base is from continuous forest inventory of clonal Eucalyptus spp. plantations, given by Aracruz Cellulose Company, located in the Brazilian costal region, Bahia and Espirito Santo states. The model precision was verified by ratio likelihood test, by mean square error (MSE and by graphical residual analysis. The results showed that the complete model with 3 parameters, developed from the original model with one regressor, was superior to the other models, due to the inclusion of stand based variables, such as: clone, total height (HT, dominant height (HD, quadratic diameter (Dg, Basal Area (G, site index (IS and Density (N, generating a new model, called Complete Model III. The improvement of the precision was highly significant when compared to another models. Consequently, this model provides information with a high degree of precision and accuracy for the forest companies planning.

  16. Developing population models with data from marked individuals

    Science.gov (United States)

    Hae Yeong Ryu,; Kevin T. Shoemaker,; Eva Kneip,; Anna Pidgeon,; Patricia Heglund,; Brooke Bateman,; Thogmartin, Wayne E.; Reşit Akçakaya,

    2016-01-01

    Population viability analysis (PVA) is a powerful tool for biodiversity assessments, but its use has been limited because of the requirements for fully specified population models such as demographic structure, density-dependence, environmental stochasticity, and specification of uncertainties. Developing a fully specified population model from commonly available data sources – notably, mark–recapture studies – remains complicated due to lack of practical methods for estimating fecundity, true survival (as opposed to apparent survival), natural temporal variability in both survival and fecundity, density-dependence in the demographic parameters, and uncertainty in model parameters. We present a general method that estimates all the key parameters required to specify a stochastic, matrix-based population model, constructed using a long-term mark–recapture dataset. Unlike standard mark–recapture analyses, our approach provides estimates of true survival rates and fecundities, their respective natural temporal variabilities, and density-dependence functions, making it possible to construct a population model for long-term projection of population dynamics. Furthermore, our method includes a formal quantification of parameter uncertainty for global (multivariate) sensitivity analysis. We apply this approach to 9 bird species and demonstrate the feasibility of using data from the Monitoring Avian Productivity and Survivorship (MAPS) program. Bias-correction factors for raw estimates of survival and fecundity derived from mark–recapture data (apparent survival and juvenile:adult ratio, respectively) were non-negligible, and corrected parameters were generally more biologically reasonable than their uncorrected counterparts. Our method allows the development of fully specified stochastic population models using a single, widely available data source, substantially reducing the barriers that have until now limited the widespread application of PVA. This method

  17. Language Development in Individuals with Fragile X Syndrome

    Science.gov (United States)

    Finestack, Lizbeth H.; Richmond, Erica K.; Abbeduto, Leonard

    2009-01-01

    Fragile X syndrome (FXS) is the leading inherited cause of intellectual disability. The syndrome is caused by a single gene mutation on the X chromosome. Although individual differences are large, most individuals with FXS display weaknesses across all language and literacy domains compared with peers of the same chronological age with typical…

  18. Developing high-performance cross-functional teams: Understanding motivations, functional loyalties, and teaming fundamentals

    Energy Technology Data Exchange (ETDEWEB)

    Miller, M.A.

    1996-08-01

    Teamwork is the key to the future of effective technology management. Today`s technologies and markets have become too complex for individuals to work alone. Global competition, limited resources, cost consciousness, and time pressures have forced organizations and project managers to encourage teamwork. Many of these teams will be cross-functional teams that can draw on a multitude of talents and knowledge. To develop high-performing cross-functional teams, managers must understand motivations, functional loyalties, and the different backgrounds of the individual team members. To develop a better understanding of these issues, managers can learn from experience and from literature on teams and teaming concepts. When studying the literature to learn about cross-functional teaming, managers will find many good theoretical concepts, but when put into practice, these concepts have varying effects. This issue of varying effectiveness is what drives the research for this paper. The teaming concepts were studied to confirm or modify current understanding. The literature was compared with a {open_quotes}ground truth{close_quotes}, a survey of the reality of teaming practices, to examine the teaming concepts that the literature finds to be critical to the success of teams. These results are compared to existing teams to determine if such techniques apply in real-world cases.

  19. Literature as Window: Developing Interracial Understanding through Fiction.

    Science.gov (United States)

    Merriam, Allen H.

    1988-01-01

    Using Chinua Achebe's "Things Fall Apart" as a case study, demonstrates the evocative power of fiction to promote interracial understanding. Creative art, by appealing to the imagination, can evoke feelings and insights that make human relationships vivid and personal. (BJV)

  20. The Impact of an Instructional Intervention Designed to Support Development of Stochastic Understanding of Probability Distribution

    Science.gov (United States)

    Conant, Darcy Lynn

    2013-01-01

    Stochastic understanding of probability distribution undergirds development of conceptual connections between probability and statistics and supports development of a principled understanding of statistical inference. This study investigated the impact of an instructional course intervention designed to support development of stochastic…

  1. The Development of Danish OHS Regulation - Organizational Understanding and Program Theory

    DEFF Research Database (Denmark)

    Seim, Rikke; Jensen, Per Langaa; Møller, Niels

    2014-01-01

    This paper focuses on a major recent amendment of the Danish Working Environment regulation concerning the cooperation of health and safety between employees and employer. The amendment, which came into force in October 2010, consists of four elements: 1) change of terminology, 2) flexibility...... in organizing OHS, 3) link between the companies’ overall strategic management and OHS and 4) continuously competence development for the health and safety representatives. In this paper we present and analyze the individual elements of the legislative amendment. Subsequent we investigate the organizational...... understanding that underlies the amendment and we explore the program theory that the different elements of the reform subscribe to....

  2. Individual-Based Compulsive Sexual Behavior Scale: Its Development and Importance in Examining Compulsive Sexual Behavior.

    Science.gov (United States)

    Efrati, Yaniv; Mikulincer, Mario

    2018-04-03

    Compulsive sexual behavior comprises individual-based (e.g., sexual fantasies, compulsive sexual thoughts, masturbation) and partnered (e.g., interpersonal sexual conquests, repeated infidelity) facets. Most instruments for assessing compulsive sexual behavior, however, focus less on the individual-based facet and specifically on fantasies and compulsive thoughts. In the current research, we developed and validated an individual-based compulsive sexual behavior scale (I-CSB). In Study 1 (N = 492), the factorial structure of the I-CSB was examined. In Study 2 (N = 406), we assessed I-CSB's convergent validity. In Study 3 (N = 112), we examined whether the I-CSB differentiates between individuals who suffer from compulsive sexual behavior and those who do not. Results revealed a four-factor structure for individual-based compulsive sexual behavior that is associated with an intense inner conflict regarding sexuality (high arousal contrasting with high sexual anxiety), and that accounts for approximately 75% of the differences between people with compulsive sexual behavior and controls. Results are discussed in light of the need for a broader understanding of compulsive sexual behavior.

  3. Intelligence and handedness: Meta-analyses of studies on intellectually disabled, typically developing, and gifted individuals.

    Science.gov (United States)

    Papadatou-Pastou, Marietta; Tomprou, Dimitra-Maria

    2015-09-01

    Understanding the relationship between cerebral laterality and intelligence is important in elucidating the neurological underpinnings of individual differences in cognitive abilities. A widely used, behavioral indicator for cerebral laterality, mainly of language, is handedness. A number of studies have compared cognitive abilities between groups of left- and right-handers, while others have investigated the handedness prevalence between groups of different cognitive abilities. The present study comprises five meta-analyses of studies that have assessed the handedness prevalence in (a) individuals with intellectual disability (ID) of unknown/idiopathic nature compared to typically developing (TD) individuals, and (b) individuals with intellectual giftedness (IG) compared to TD individuals. Nineteen data sets totaling 16,076 participants (5795 ID, 8312 TD, and 1969 IG) were included in the analyses. Elevated levels of atypical handedness were found to be robust only for the ID to TD comparison. Findings constrain the range of acceptable theories on the handedness distribution for different intelligence levels. Copyright © 2015 Elsevier Ltd. All rights reserved.

  4. Distinctive laterality of neural networks supporting action understanding in left- and right-handed individuals: An EEG coherence study.

    Science.gov (United States)

    Kelly, Rachel; Mizelle, J C; Wheaton, Lewis A

    2015-08-01

    Prior work has demonstrated that perspective and handedness of observed actions can affect action understanding differently in right and left-handed persons, suggesting potential differences in the neural networks underlying action understanding between right and left-handed individuals. We sought to evaluate potential differences in these neural networks using electroencephalography (EEG). Right- and left-handed participants observed images of tool-use actions from egocentric and allocentric perspectives, with right- and left-handed actors performing the actions. Participants judged the outcome of the observed actions, and response accuracy and latency were recorded. Behaviorally, the highest accuracy and shortest latency was found in the egocentric perspective for right- and left-handed observers. Handedness of subject showed an effect on accuracy and latency also, where right-handed observers were faster to respond than left-handed observers, but on average were less accurate. Mu band (8-10 Hz) cortico-cortical coherence analysis indicated that right-handed observers have coherence in the motor dominant left parietal-premotor networks when looking at an egocentric right or allocentric left hands. When looking in an egocentric perspective at a left hand or allocentric right hand, coherence was lateralized to right parietal-premotor areas. In left-handed observers, bilateral parietal-premotor coherence patterns were observed regardless of actor handedness. These findings suggest that the cortical networks involved in understanding action outcomes are dependent on hand dominance, and notably right handed participants seem to utilize motor systems based on the limb seen performing the action. The decreased accuracy for right-handed participants on allocentric images could be due to asymmetrical lateralization of encoding action and motoric dominance, which may interfere with translating allocentric limb action outcomes. Further neurophysiological studies will

  5. Developing Understanding of Mathematical Modeling in Secondary Teacher Preparation

    Science.gov (United States)

    Anhalt, Cynthia Oropesa; Cortez, Ricardo

    2016-01-01

    This study examines the evolution of 11 prospective teachers' understanding of mathematical modeling through the implementation of a modeling module within a curriculum course in a secondary teacher preparation program. While the prospective teachers had not previously taken a course on mathematical modeling, they will be expected to include…

  6. Developing a Logotherapeutic Model for understanding Victims of ...

    African Journals Online (AJOL)

    Presently, there is no available logotherapeutic model for understanding the experiences of persons in crises, specifically the victims of sexual assault in Nigeria. The paper first reviewed the literature on some of the available models: equilibrium, cognitive and psychosocial transition. The author has added the ...

  7. DEVELOPING A BETTER UNDERSTANDING OF REAL-WORLD AUTOMOBILE EMISSIONS

    Science.gov (United States)

    Emission inventories are needed by EPA for air dispersion modeling, regional strategy development, regulation setting, air toxics risk assessment, and trend tracking. Therefore, it is extremely important that inventories be accurate and be updated frequently. The development an...

  8. Developments in the scientific and clinical understanding of fibromyalgia

    OpenAIRE

    Buskila, Dan

    2009-01-01

    Our understanding of fibromyalgia (FM) has made significant advances over the past decade. The current concept views FM as the result of central nervous system malfunction resulting in amplification of pain transmission and interpretation. Research done over the past years has demonstrated a role for polymorphisms of genes in the serotoninergic, dopaminergic and catecholaminergic systems in the etiopathogenesis of FM. Various external stimuli such as infection, trauma and stress may contribut...

  9. An Integrative Approach to Developing Organisational Capabilities and Individual Skills

    OpenAIRE

    Murnane, Sinéad; Thornley, Clare

    2017-01-01

    The tightly coupled relationship between organisational capability and the skills and competences of the individuals working in that organisation has long been recognised in both the academic literature and by the practitioner community. Simply improving individuals’ skills and hoping that the organisation’s capability automatically improves in tandem is not sufficient, however. This relationship is non-trivial and needs to be actively managed, meaning that people need to have shared goals ...

  10. Developing a SNP panel for forensic identification of individuals

    DEFF Research Database (Denmark)

    Kidd, KK; Pakstis, AJ; Speed, WC

    2006-01-01

    of genetic variation from the world's major geographical regions. Those with little allele frequency variation on the seven populations are then screened on a total of 40 populations ( approximately 2100 individuals) and the most promising retained. The preliminary panel of 19 SNPs, from an initial selection...... of 195 SNPs, gives an average match probability of panel to approximately 50 comparable SNPs should give match probabilities of about 10(-15) with a small global range....

  11. Leadership development of individuals with developmental disabilities in the self-advocacy movement.

    Science.gov (United States)

    Caldwell, J

    2010-11-01

    Exploring the life stories of leaders in the self-advocacy movement can expand our knowledge about leadership development of individuals with developmental disabilities. A better understanding of this process may assist with supporting the movement and leadership development of youth with disabilities. In-depth qualitative interviews were conducted with 13 leaders in the self-advocacy movement within the USA in order to explore their life stories. Purposeful sampling contributed to a diverse sample of leaders. A grounded theory approach led to the identification of major themes and factors associated with their leadership development. Four major themes emerged: (1) disability oppression and resistance; (2) environmental supports and relationships; (3) leadership skills; and (4) advanced leadership opportunities. Findings have conceptual and practical relevance for future interventions and research. © 2010 The Author. Journal of Intellectual Disability Research © 2010 Blackwell Publishing Ltd.

  12. Racial identity invalidation with multiracial individuals: An instrument development study.

    Science.gov (United States)

    Franco, Marisa G; O'Brien, Karen M

    2018-01-01

    Racial identity invalidation, others' denial of an individual's racial identity, is a salient racial stressor with harmful effects on the mental health and well-being of Multiracial individuals. The purpose of this study was to create a psychometrically sound measure to assess racial identity invalidation for use with Multiracial individuals (N = 497). The present sample was mostly female (75%) with a mean age of 26.52 years (SD = 9.60). The most common racial backgrounds represented were Asian/White (33.4%) and Black/White (23.7%). Participants completed several online measures via Qualtrics. Exploratory factor analyses revealed 3 racial identity invalidation factors: behavior invalidation, phenotype invalidation, and identity incongruent discrimination. A confirmatory factor analysis provided support for the initial factor structure. Alternative model testing indicated that the bifactor model was superior to the 3-factor model. Thus, a total score and/or 3 subscale scores can be used when administering this instrument. Support was found for the reliability and validity of the total scale and subscales. In line with the minority stress theory, challenges with racial identity mediated relationships between racial identity invalidation and mental health and well-being outcomes. The findings highlight the different dimensions of racial identity invalidation and indicate their negative associations with connectedness and psychological well-being. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  13. Individualized Physical 3-dimensional Kidney Tumor Models Constructed From 3-dimensional Printers Result in Improved Trainee Anatomic Understanding.

    Science.gov (United States)

    Knoedler, Margaret; Feibus, Allison H; Lange, Andrew; Maddox, Michael M; Ledet, Elisa; Thomas, Raju; Silberstein, Jonathan L

    2015-06-01

    To evaluate the effect of 3-dimensionally (3D) printed physical renal models with enhancing masses on medical trainee characterization, localization, and understanding of renal malignancy. Proprietary software was used to import standard computed tomography (CT) cross-sectional imaging into 3D printers to create physical models of renal units with enhancing renal lesions in situ. Six different models were printed from a transparent plastic resin; the normal parenchyma was printed in a clear, translucent plastic, with a red hue delineating the suspicious renal lesion. Medical students, who had completed their first year of training, were given an overview and tasked with completion of RENAL nephrometry scores, separately using CT imaging and 3D models. Trainees were also asked to complete a questionnaire about their experience. Variability between trainees was assessed by intraclass correlation coefficients (ICCs), and kappa statistics were used to compare the trainee to experts. Overall trainee nephrometry score accuracy was significantly improved with the 3D model vs CT scan (P <.01). Furthermore, 3 of the 4 components of the nephrometry score (radius, nearness to collecting system, and location) showed significant improvement (P <.001) using the models. There was also more consistent agreement among trainees when using the 3D models compared with CT scans to assess the nephrometry score (intraclass correlation coefficient, 0.28 for CT scan vs 0.72 for 3D models). Qualitative evaluation with questionnaires filled out by the trainees further confirmed that the 3D models improved their ability to understand and conceptualize the renal mass. Physical 3D models using readily available printing techniques improve trainees' understanding and characterization of individual patients' enhancing renal lesions. Published by Elsevier Inc.

  14. Immune system of Chernobyl children: Developments in understanding

    International Nuclear Information System (INIS)

    Strauss, K.; Chernyshov, V.P.; Vychovanets, E.V.; Antipkin, Y.G.; Klimenko, E.P.; Vasyuk, A.N.; Slukvin, I.I.

    1997-01-01

    It is generally recognized that explosive increase thyroid malignancy rate among individuals who were children at the time of Chernobyl accident can be directly linked to the released radiation, especially to iodine isotopes. Radioactive iodine comprise a major component of total body radiation received following exposure to fallout from nuclear plant accident. In addition to thyroid cancer, ionizing radiation and radioactive isotopes of iodine is known to cause thyroid dysfunction. It was demonstrated that exposure to radioactive isotopes of iodine following treatment of hyperthyroidism or after exposure to fallout from hydrogen bomb explosion can induce hypothyroidism in human. 15 refs, 7 tabs

  15. Understanding the Causal Links between Financial Development and International Trade

    OpenAIRE

    Youssouf KIENDREBEOGO

    2012-01-01

    This paper analyses the causal relationship between financial development and international trade using data of 21 developed and developing countries from 1961 to 2010 and appropriate time series techniques that allow us to decompose the source of causation according to the order of integration of the variables and the possible presence of a cointegrating relationship. We analyze in detail the issue of integration of our series in order to use the most appropriate stationarisation techniques ...

  16. Understanding and education of nuclear power development issues in China

    International Nuclear Information System (INIS)

    Zhang Jing

    1993-01-01

    This paper describes the introduction of nuclear power to China; the understanding of nuclear power in China, education of nuclear power among chinese people. Through such efforts of The Chinese Nuclear Association the Chinese people already have the basic knowledge and support the nuclear power in general. But there are about fifty percent of people who do not know the nuclear power stations in China and thirty-six percent who do not know the benefit of nuclear power because of the vast and different education level in some undeveloped rural areas where the education can not reach

  17. Teaching secondary science constructing meaning and developing understanding

    CERN Document Server

    Ross, Keith; McKechnie, Janet

    2010-01-01

    Now fully updated in its third edition Teaching Secondary Science is a comprehensive guide to all aspects of science teaching, providing a wealth of information and ideas about different approaches. With guidance on how children understand scientific ideas and the implications this has on teaching, teachers are encouraged to construct their own meanings and become reflective in their practice. Relating science to government agendas, such as the National Strategies, Assessment for Learning and Every Child Matters, this new edition reflects and maps to changes in national standards. Ke

  18. Understanding the experiences and needs of individuals with Spinal Muscular Atrophy and their parents: a qualitative study.

    Science.gov (United States)

    Qian, Ying; McGraw, Sarah; Henne, Jeff; Jarecki, Jill; Hobby, Kenneth; Yeh, Wei-Shi

    2015-10-24

    The clinical features of SMA, which range along a spectrum of severity, are relatively well described. In contrast, the literature on how individuals with SMA and their families experience this condition is limited. To address this gap, we undertook a qualitative study with individuals affected by SMA Types I, II and III, parents of those affected, and clinicians. We completed 16 focus group sessions and 37 interviews in the US with 96 participants including: 21 with individuals with SMA; 64 parents of individuals affected by SMA; and 11 clinicians who specialize in the care of SMA patients. The Diagnostic Journey: Families reported substantial diagnostic delays owing to: 1) lack of awareness and knowledge about SMA; 2) the difficulty of distinguishing normal from abnormal development; and 3) the challenge of differential diagnosis. Lack of sensitivity in how clinicians communicated this potentially devastating diagnosis compounded parents' negative impressions. Newborn Screening: Parents generally held positive views about adding SMA to newborn screening panels. For example, it would: 1) enable earlier access to care; 2) shorten the diagnostic journey; and 3) give families more time to prepare to care for a disabled child. Some noted negative outcomes such as prematurely affecting a parent's relationship with a child before symptoms are evident. The Psychosocial Impact of Living with SMA: Ten thematic areas characterized the impact: 1) confronting premature death; 2) making difficult treatment choices; 3) fearing the loss of functional ability; 4) coming to terms with lost expectations; 5) loss of sleep and stress; 6) stigma; 7) limitations on social activities; 8) independence; 9) uncertainty and helplessness; and 10) family finances. The results of this study suggest high levels of burden experienced by individuals with SMA and their families. The difficulties of living with SMA begin with the long and often arduous process of finding a diagnosis for their child

  19. Understanding Economic and Management Sciences Teachers' Conceptions of Sustainable Development

    Science.gov (United States)

    America, Carina

    2014-01-01

    Sustainable development has become a key part of the global educational discourse. Education for sustainable development (ESD) specifically is pronounced as an imperative for different curricula and regarded as being critical for teacher education. This article is based on research that was conducted on economic and management sciences (EMS)…

  20. Understanding Emotional Development: Helping Early Childhood Providers Better Support Families

    Science.gov (United States)

    Edwards, Nicole Megan

    2012-01-01

    This article is intended to provide early childhood providers with a concise overview of emerging emotional development in young children (birth-5), the important role of primary caregivers, and the link between parenting, emotional development, and behavior. Specific suggestions that have been shared with urban Head Start mothers are offered,…

  1. Understanding Acceptance of Software Metrics--A Developer Perspective

    Science.gov (United States)

    Umarji, Medha

    2009-01-01

    Software metrics are measures of software products and processes. Metrics are widely used by software organizations to help manage projects, improve product quality and increase efficiency of the software development process. However, metrics programs tend to have a high failure rate in organizations, and developer pushback is one of the sources…

  2. Immune system inflammation in cocaine dependent individuals: implications for medications development

    Science.gov (United States)

    Fox, Helen C.; D’Sa, Carrol; Kimmerling, Anne; Siedlarz, Kristen M.; Tuit, Keri L.; Stowe, Raymond; Sinha, Rajita

    2013-01-01

    Objectives Cocaine dependence is a chronic stress state. Furthermore, both stress and substance abuse have robust and reciprocal effects on immune system cytokines, which are known to be powerful modulators of mood. We therefore examine basal and provoked changes in peripheral cytokines in cocaine dependent individuals to better understand their role in the negative reinforcing effects of cocaine. Methods Twenty-eight (16 F/12 M) treatment-seeking cocaine dependent individuals and 27 (14 F/13 M) social drinkers were exposed to three 5-min guided imagery conditions (stress, drug cue, relaxing) presented randomly across consecutive days. Measures of salivary cortisol, tumor necrosis factor alpha (TNFα), interleukin-10 (IL-10), and interleukin-1 receptor antagonist (IL-1ra) were collected at baseline and various post-imagery time-points. Results Cocaine abusers demonstrated decreased basal IL-10 compared with social drinkers. They also showed significant elevations in pro-inflammatory TNFα when exposed to stress compared with when they were exposed to relaxing imagery. This was not observed in the social drinkers. Conversely, social drinkers demonstrated increases in the anti-inflammatory markers, IL-10 and IL-1ra, following exposure to cue, which were not seen in the dependent individuals. Conclusions Cocaine dependent individuals demonstrate an elevated inflammatory state both at baseline and following exposure to the stress imagery condition. Cytokines may reflect potentially novel biomarkers in addicted populations for treatment development. PMID:22389080

  3. Understanding the mechanism of base development of HSQ

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jihoon; Chao, Weilun; Griedel, Brian; Liang, Xiaogan; Lewis, Mark; Hilken, Dawn; Olynick, Deirdre

    2009-06-16

    We study the dissolution mechanism of HSQ (hydrogen silsesquioxane) in base solutions with the addition of chloride salts to elucidate the development mechanism. Reaction mechanisms are proposed based on the dissolution mechanism of quartz. Development kinetics points to two dose-dependent development mechanisms. Considering ion sizes, both hydrated and non-hydrated, and ion exchange, we propose that a combination of a surface dominated reaction at higher doses and a matrix dominated reaction at lower doses accounts for the high development contrast with a NaOH base/NaCl salt mixture. The interplay between the hydrated and non-hydrated ion size leads to higher contrast developers, such as tetramethyl ammonium hydroxide (TMAH) with NaCl.

  4. Understanding Teaching Development Programs - the why and how they work

    DEFF Research Database (Denmark)

    Rump, Camilla Østerberg; Christiansen, Frederik V; Trigwell, Keith

    of teaching and innovation addressed, approaches to teaching (AT) using all 5 qualitative categories, self-efficacy beliefs (SEBs), institutional context of teaching , experience thereof, and strategies for dealing with it. Results show satisfactory outcome, and reveal interesting relationships between AT......Teaching development programs (TDPs) seem like a natural way to develop innovative teaching and learning environments. In the local programs of the authors, the participants do a project in the second semester of participation. In the project, the participants are required to plan, carry out......, and evaluate some form of student centered teaching, and innovative teaching formats are encouraged and often developed. However, the wider institutional impact of these developments is difficult to assess. Even though a number of primarily quantitative studies show generally positive results, only small...

  5. Understanding community benefit payments from renewable energy development

    International Nuclear Information System (INIS)

    Kerr, Sandy; Johnson, Kate; Weir, Stephanie

    2017-01-01

    It is increasingly common for renewable energy projects to make financial, or in kind, payments to local communities. These arrangements are variously described as ‘benefits payments’ or ‘compensation schemes’. Similar approaches are now being recommended for other forms of development with potential to engender opposition from local communities (e.g. nuclear power and fracking). While such payments are common, the level of payment, the institutional frameworks involved, and the nature of discourse, varies greatly. Existing literature has sought to record, rather than explain, the diversity of arrangements. To a large extent this diversity is rooted in the power dynamic between developer and community. Three UK case studies are used to highlight the diversity of arrangements, meanings, and power balances, within benefits arrangements. Finally, a typology is developed to illustrate the spectrum of potential arrangements. This typology gives insight into why various arrangements emerge in response to their specific contexts. - Highlights: • There are increasing expectations that energy projects will deliver community benefit payments. • In practice benefit arrangements display high levels of heterogeneity. • Much of this diversity can be explained by the power dynamic between developer and community. • A typology is developed to illustrate the spectrum of potential arrangements.

  6. Understanding Mammalian Germ Line Development with In Vitro Models.

    Science.gov (United States)

    Martínez-Arroyo, Ana M; Míguez-Forján, Jose M; Remohí, Jose; Pellicer, Antonio; Medrano, Jose V

    2015-09-15

    Germ line development is crucial in organisms with sexual reproduction to complete their life cycle. In mammals, knowledge about germ line development is based mainly on the mouse model, in which genetic and epigenetic events are well described. However, little is known about how germ line development is orchestrated in humans, especially in the earliest stages. New findings derived from human in vitro models to obtain germ cells can shed light on these questions. This comprehensive review summarizes the current knowledge about mammalian germ line development, emphasizing the state of the art obtained from in vitro models for germ cell-like cell derivation. Current knowledge of the pluripotency cycle and germ cell specification has allowed different in vitro strategies to obtain germ cells with proven functionality in mouse models. Several reports during the last 10 years show that in vitro germ cell derivation with proven functionality to generate a healthy offspring is possible in mice. However, differences in the embryo development and pluripotency potential between human and mouse make it difficult to extrapolate these results. Further efforts on both human and mouse in vitro models to obtain germ cells from pluripotent stem cells may help to elucidate how human physiological events take place; therefore, therapeutic strategies can also be considered.

  7. Developing a SNP panel for forensic identification of individuals

    DEFF Research Database (Denmark)

    Kidd, KK; Pakstis, AJ; Speed, WC

    2006-01-01

    and characterizing such SNPs, and test that strategy on a broad representation of world populations. Markers with high heterozygosity and little frequency variation among African American, European American, and East Asian populations are selected for additional screening on seven populations that provide a sampling...... of genetic variation from the world's major geographical regions. Those with little allele frequency variation on the seven populations are then screened on a total of 40 populations ( approximately 2100 individuals) and the most promising retained. The preliminary panel of 19 SNPs, from an initial selection......, because allele frequencies can vary greatly among populations, the population genetics of match probabilities is a critical issue. Some SNPs, however, show little allele frequency variation among populations while remaining highly informative. We describe here both an efficient strategy for identifying...

  8. 45 CFR 1308.19 - Developing individualized education programs (IEPs)

    Science.gov (United States)

    2010-10-01

    ... present level of functioning in the social-emotional, motor, communication, self-help, and cognitive areas... HUMAN DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN...

  9. Understanding the Amazon Hydrology for Sustainable Hydropower Development

    Science.gov (United States)

    Pokhrel, Y. N.; Chaudhari, S. N.

    2017-12-01

    Construction of 147 new hydropower dams, many of which are large, has been proposed in the Amazon river basin, despite the continuous stacking of negative impacts from the existing ones. These dams are continued to be built in a way that disrupts river ecology, causes large-scale deforestation, and negatively affects both the food systems nearby and downstream communities. In this study, we explore the impacts of the existing and proposed hydropower dams on the hydrological fluxes across the Amazonian Basin by incorporating human impact modules in an extensively validated regional hydrological model called LEAF-Hydro-Flood (LHF). We conduct two simulations, one in offline mode, forced by observed meteorological data for the historical period of 2000-2016 and the other in a coupled mode using the Weather Research and Forecasting (WRF) regional climate model. We mainly analyze terrestrial water storage and streamflow changes during the period of dam operations with and without human impacts. It is certain that the Amazon will undergo some major hydrological changes such as decrease in streamflow downstream in the coming decades caused due to these proposed dams. This study helps us understand and represent processes in a predictable manner, and provides the ability to evaluate future scenarios with dams and other major human influences while considering climate change in the basin. It also provides important insights on how to redesign the hydropower systems to make them truly renewable in terms of energy production, hydrology and ecology.

  10. Developing Academic Literacies through Understanding the Nature of Disciplinary Knowledge

    Science.gov (United States)

    Clarence, Sherran; McKenna, Sioux

    2017-01-01

    Much academic development work that is framed by academic literacies, especially that focused on writing, is concerned with disciplinary conventions and knowledges: conceptual, practical, and procedural. This paper argues, however, that academic literacies work tends to conflate literacy practices with disciplinary knowledge structures, thus…

  11. Emergent Comprehension: Understanding Comprehension Development among Young Literacy Learners

    Science.gov (United States)

    McMunn Dooley, Caitlin; Matthews, Mona W.

    2009-01-01

    This article hones what is meant by "emergent comprehension". The authors define emergent comprehension as the period when young children, prior to conventional reading, engage in meaningful experiences that stimulate the development and use of meaning-making strategies with potential to affect later reading comprehension. The construct "emergent…

  12. Understanding place brands as collective and territorial development processes

    NARCIS (Netherlands)

    Donner, M.I.M.

    2016-01-01

    Place branding strategies linking marketing to places have received increasing attention in practice and theory in the past two decades. It is generally assumed that place branding contributes to the economic, social, political and cultural development of cities, regions and countries. But there

  13. Understanding place brands as collective and territorial development processes

    NARCIS (Netherlands)

    Donner, M.I.M.

    2016-01-01

    Place branding strategies linking marketing to places have received increasing attention in practice and theory in the past two decades. It is generally assumed that place branding contributes to the economic, social, political and cultural development of cities, regions and countries. But there

  14. Understanding Personality Development: An Integrative State Process Model

    Science.gov (United States)

    Geukes, Katharina; van Zalk, Maarten; Back, Mitja D.

    2018-01-01

    While personality is relatively stable over time, it is also subject to change across the entire lifespan. On a macro-analytical level, empirical research has identified patterns of normative and differential development that are affected by biological and environmental factors, specific life events, and social role investments. On a…

  15. School library development and an understanding of information ...

    African Journals Online (AJOL)

    This study examined the extent to which school library development correlates with information literacy competencies among students in selected Secondary Schools in Nigeria. The study design is correctional design. This study was predicated on a theoretical framework of Marlands Steps to research inform of nine ...

  16. Understanding the Career Development of Underprepared College Students

    Science.gov (United States)

    Hughes, Amber N.; Gibbons, Melinda M.

    2018-01-01

    The purpose of this study was to examine the career development of underprepared college students using relational career theory. Specifically, the constructs of family influence, locus of control, and career decision-making self-efficacy were explored as they relate to perceived success in college. Significant correlations between external locus…

  17. Understanding the Organizational Context of Academic Program Development

    Science.gov (United States)

    Dee, Jay R.; Heineman, William A.

    2016-01-01

    This chapter provides a conceptual model that academic leaders can use to navigate the complex, and often contentious, organizational terrain of academic program development. The model includes concepts related to the institution's external environment, as well as internal organizational structures, cultures, and politics. Drawing from the…

  18. Developing a Frame of Reference for understanding configuration systems

    DEFF Research Database (Denmark)

    Ladeby, Klaes Rohde; Edwards, Kasper

    2008-01-01

    This paper uses the theory of technical systems to develop a frame of reference of product configuration systems. Following a definition of the configuration task, product model and product configuration system the theory of technical systems are presented. Configuration systems are then related...

  19. Understanding the role of Dicer in astrocyte development

    OpenAIRE

    Fu, Ying-Hui; Howng, SYB; Huang, Y; Ptáček, L; Fu, YH

    2015-01-01

    © 2015 Howng et al.The Dicer1 allele is used to show that microRNAs (miRNAs) play important roles in astrocyte development and functions. While it is known that astrocytes that lack miRNAs are dysregulated, the in vivo phenotypes of these astrocytes are no

  20. Understanding regional metabolism for a sustainable development of urban systems.

    Science.gov (United States)

    Baccini, P

    1996-06-01

    Cities are the most complex forms of settlements which man has built in the course of his cultural development. Their "metabolism" is connected with the world economy and is run mainly by fossil energy carriers. Up to now there are no validated models for the evaluation of a sustainable development of urban regions.The guidelines for a "sustainable development" suggest the reduction of resource consumption. The article is concerned with the problem of how the "sustainable-development concept" can be transformed from a global to a regional scale. In urban settlements the strategy of final storage should be applied. By this, the subsystem waste management can be transformed within 10 to 15 years to a "sustainable status".With regard to the system "agronomy", the article concludes that agriculture in urban systems should focus on food production instead of promoting reduction of food production in favour of energy plants, which is not a suitable strategy.The main problems are the energy carriers. Transformation to a "sustainble status" is only possible by a reconstruction of the urban system, i.e. of buildings and the transportation network. The rate determining step in achieving such a status is the change in the fabric of buildings and in the type of transportation networks. The reconstruction of an urban system needs, mainly for economical reasons, a time period of two generations.

  1. Understanding partnerships in developing disabled entrepreneurs through participatory action research.

    Science.gov (United States)

    Van Niekerk, L; Lorenzo, T; Mdlokolo, P

    2006-03-15

    The paper reports on a community disability entrepreneurship project in Khayelitsha and Nyanga, Cape Town, South Africa. Disabled people, Disabled People South Africa ( a national organization made up by disabled people's organizations), a non-governmental organisation and occupational therapists from the University of Cape Town collaborated with the focus to achieve economic empowerment of disabled people though the establishment of micro-enterprises. Participatory Action Research strategies, which informed and monitored the effective development of the community disability entrepreneurship project, were carefully integrated with the existing principles of community development. The participatory action research process provided an opportunity for shared learning and development. This article reports on the challenges and strategies faced by disabled people in the quest to establish themselves as entrepreneurs. The challenges that were identified through analysis from the experiences of participants were starting with nothing, lack of capacity and complexity of establishing working relationships. The strategies used were building group identity and developing capacity together. Indicators of positive outcome that emerged from an inductive content analysis are presented and discussed.

  2. Understanding the Development of School Psychology in Mainland China

    Science.gov (United States)

    D'Amato, Rik Carl; van Schalkwyk, Gertina J.; Zhao, B. Yang; Hu, Juan

    2013-01-01

    School psychology is an important area within psychology, which has a short developmental history in Mainland China. Nonetheless, along with economic advances and social changes in Mainland China, school psychology is developing and becoming more important. Currently, people need to work harder and longer. This places many under pressure that may…

  3. Understanding Teaching Development Programs - the why and how they work

    DEFF Research Database (Denmark)

    Rump, Camilla Østerberg; Christiansen, Frederik V; Trigwell, Keith

    impacts are reported, and the question of why and how the programs work is not addressed. This study is based on 79 participant projects and interviews with 19 teachers of which 9 also did one of the participant projects. The data was analyzed in relation to specific learning outcome and level, types......Teaching development programs (TDPs) seem like a natural way to develop innovative teaching and learning environments. In the local programs of the authors, the participants do a project in the second semester of participation. In the project, the participants are required to plan, carry out...... of teaching and innovation addressed, approaches to teaching (AT) using all 5 qualitative categories, self-efficacy beliefs (SEBs), institutional context of teaching , experience thereof, and strategies for dealing with it. Results show satisfactory outcome, and reveal interesting relationships between AT...

  4. Hiring, Developing, and Organizing Individual Employees for New Product Development versus Product-related Service Innovation

    DEFF Research Database (Denmark)

    Knudsen, Mette Præst; Schleimer, Stephanie

    outcomes. An analysis of 335 survey responses of the multi-topic and multi-country European Manufacturing Survey (EMS) results in a number of interesting findings. First and foremost, although there are commonalities in organizing employees in flexible team arrangements for new product development versus...... product-related service innovations, there are also important differences between these. In particular, whilst the educational level of employees has a significant and positive effect on new product development success, hiring highly educated individuals has a significant and negative effect on new...... the value of human resource hiring and developing practices for new product development success; organizations will find it more beneficial to invest predominantly in employees with the highest possible educational level, whilst for product-related service innovations; employees with more general skills...

  5. From Individual Differences to Dynamic Pathways of Development.

    Science.gov (United States)

    Fischer, Kurt W.; Pare-Blagoev, Juliana

    2000-01-01

    Suggests ways to use dynamic systems analysis to illuminate the pluralistic and multidimensional model described by Larivee, Normandeau, and Parent (2000). Issues discussed include the characteristics of developmental transitions, such as hysteresis; nature of growth processes, such as hierarchical development or predator-prey interactions; and…

  6. Studying Individual and Family Development: Linking Theory and Research

    Science.gov (United States)

    O'Brien, Marion

    2005-01-01

    The predominant theoretical orientation of the majority of scientists studying human behavioral development and family functioning is derived from systems models. These theories are dynamic in their conceptualization and emphasize process and context. To a large extent, the analytic strategies we employ are not consistent with our theoretical…

  7. Toward Understanding Dynamics in Shifting Biomes: An Individual Based Modeling Approach to Characterizing Drought and Mortality in Central Western Canada

    Science.gov (United States)

    Armstrong, A. H.; Foster, A.; Rogers, B. M.; Hogg, T.; Michaelian, M.; Shuman, J. K.; Shugart, H. H., Jr.; Goetz, S. J.

    2017-12-01

    The Arctic-Boreal zone is known be warming at an accelerated rate relative to other biomes. Persistent warming has already affected the high northern latitudes, altering vegetation productivity, carbon sequestration, and many other ecosystem processes and services. The central-western Canadian boreal forests and aspen parkland are experiencing a decade long drought, and rainfall has been identified as a key factor controlling the location of the boundary between forest and prairie in this region. Shifting biome with related greening and browning trends are readily measureable with remote sensing, but the dynamics that create and result from them are not well understood. In this study, we use the University of Virginia Forest Model Enhanced (UVAFME), an individual-based forest model, to simulate the changes that are occurring across the southern boreal and parkland forests of west-central Canada. We present a parameterization of UVAFME for western central Canadian forests, validated with CIPHA data (Climate Change Impacts on the Productivity and Health of Aspen), and improved mortality. In order to gain a fine-scale understanding of how climate change and specifically drought will continue to affect the forests of this region, we simulated forest conditions following CMIP5 climate scenarios. UVAFME predictions were compared with statistical models and satellite observations of productivity across the landscape. Changes in forest cover, forest type, aboveground biomass, and mortality and recruitment dynamics are presented, highlighting the high vulnerability of this region to vegetation transitions associated with future droughts.

  8. Managing Computer Systems Development: Understanding the Human and Technological Imperatives.

    Science.gov (United States)

    1985-06-01

    tjq~ 2hancze, John-Wiley and sons, Inc 9B 12. Beckhard ~ Richard and Harris, Reuben Top 13. DeMarco, T., Sjruj~ed An 1 s is and L.in 150 14. Dickover...information system development. Beckhard and Harris [Ref. 12: pp. 16-19] identify two essential conditions for any change effort to be effectively managed...February 19814. 10. Nolan, Richard Lo, "Controlling the Costs of Data Services," j&KjX Bisinoss Reviews July-August 1977. 11. Tichy, NoelrM : ia~gn

  9. The use of dialogic electronic journal writing to develop students' understanding of chemical bonding

    Science.gov (United States)

    English, Sarah Collard

    The intent of this study is to examine how the implementation of a dialogic electronic journal writing environment continues the development of students' understanding of chemistry, specifically chemical bonding, through written communication between the individual students and their chemistry teacher. This study is framed within a constructivist theoretical context where students' understanding is constructed through written discussions with the educator, the students' interaction with the classroom environment, and his/her interaction with the computer environment. The research design of collective case study was employed to allow multiple perspectives and processes conveyed by the participants to be examined in the context in which they occurred while considering multiple sources of information. Data sources included electronic journal entries, classroom artifacts, and semi-structured interviews. Data were analyzed using the constant comparative method, which involved coding, categorizing, and interpreting for patterns and relationships. Four cases were reported in detail. This study found that the dialogic electronic journal-writing environment was an effective venue in revealing previously undiscovered students' alternative conceptions of chemical bonding. Opportunities to actively confront and reconcile such conceptions were afforded through educator/student dialogic written interaction. The dialogic electronic journal-writing environment was also critical in the identification of gaps in students' conceptual understanding linked to improper sequencing of chemistry content. This study also found that the on-line environment provided the educator the opportunity to scaffold chemical bonding concepts to meet the needs of the students involved in the study. This study concluded that the dialogic electronic journal-writing environment positively contributed to the development of student understanding. These findings may have practical implications for teachers in

  10. A genetic approach to understanding asthma and lung function development

    DEFF Research Database (Denmark)

    Kreiner-Møller, Eskil

    2014-01-01

    Asthma is a common heritable disease of the airways with recurrent episodes of symptoms and reversible airflow obstruction that has increased dramatically in prevalence. The disease is highly heterogeneous with varying age at onset and clinical presentation and most likely represents several...... their effect. In paper I, we investigated the known effect of adult lung function loci on the development of lung function and bronchial responsiveness in children from birth until 7 years of age in the COPSAC2000 birth cohort of 411 children. We measured lung function and bronchial responsiveness at one month...... of age using the raised volume rapid thoracoabdominal compression technique in sedated neonates and repeated the measurements at age 7 utilizing traditional spirometry assessments. Lung function genetic variants identified in adults were not associated with neonatal lung function or bronchial...

  11. Individual Readiness for Organizational Change and Its Implications for Human Resource and Organization Development

    Science.gov (United States)

    Choi, Myungweon; Ruona, Wendy E. A.

    2011-01-01

    Individual readiness for organizational change reflects the concept of "unfreezing" proposed by Lewin (1947/1997b) and is critical to successful change implementation. Understanding the conditions conducive to individual readiness for organizational change, instead of the more traditional focus on resistance to change, can be useful for designing…

  12. Biracial Identity Development: A Case of Black-Korean Biracial Individuals in Korea

    Science.gov (United States)

    Kim, Hyein Amber

    2016-01-01

    This study examines two cases of Black-Korean biracial individuals and 4 Black-Korean biracial public figures who were playing influential roles in South Korea (Yoon Mi-Rae, Hines Ward, Insooni, and Moon Taejong). The purpose of this study was to understand how Black-Korean biracial individuals construct their identities, how they navigate various…

  13. Geopolitical understanding of South Korea: development, tendencies and perspectives

    Directory of Open Access Journals (Sweden)

    Roberto Celaya Figueroa

    2007-06-01

    Full Text Available The development of South Korea must be understood to the light of the environmental theories that insist on the paper of environment, including the geography and the culture, like conditioners of the political relations. The history of South Korea is confined in the history of the nations that from the opening from East to the West in the middle of century XIX play a important role like scene and reason for conflicts between the regional powers and, after 2ª World War, like scene of the conflict between the two superpowers. The objective of the present work is present Korea like a typical scene of the game of powers that represent geopolitics, for such effect is divided in three approaches: first it has to do with the geography of Korea like a strategic zone disputed by China, Japan and Russia in the middle of century XIX? the second approach talks about to the location of Korea like a geopolitical space where the two great triumphant ideologies of 2ª World War, Communism and Capitalism, and where a fight by this territory like political flag would be carried out? finally, the third approach talks about to the situation of two Coreas after the cold war locating the possible context of a possible reunification as well as scenes.

  14. Development of Web based system for individual internal monitoring programme

    International Nuclear Information System (INIS)

    Lima, Vanessa Rogeria de

    2007-01-01

    The purposes of the internal monitoring, in general, are to verify and document that each worker is protected adequately against risks from radionuclide intakes and the protection complies with legal requirements. Therefore, an overall radiation protection programme, starts with an assessment to identify work situations in which there is a risk of internal contamination of workers and to quantify the likely intake of radioactive material and the resulting committed effective dose. As a part of a continuous improvement of the monitoring programme for occupationally exposed workers at IPEN, it is being developed a Web based system to access the internal dosimetry database. The system was implemented using Hypertext Preprocessor, PHP, and a PostgreSQL database. This system will introduce a new paradigm in the routine of the internal dosimetry service, providing a fast access to the information among the measurement laboratories staff, dose evaluation group and the radiation protection supervisor. The database maintains information about worker identification, physical and chemical characteristics of the radionuclide, type of monitoring, measurement data and the dose. Moreover, this information will be readily available to provide support for regulatory compliance and quality control requirements. (author)

  15. Globalisation, the development of constitutionalism and the individual employer

    Directory of Open Access Journals (Sweden)

    K Calitz

    2007-11-01

    Full Text Available To establish which legal system will govern the relationship between parties involved in an international employment contract, the rules of private international law (or conflict of laws must be applied. Each country has its own rules of private international law and each country’s courts will apply its own rules if the court is seized with a matter that involves foreign elements. There may be conflict between the potentially applicable legal systems of countries in terms of the level of protection afforded to employees who are parties to international employment contracts. South Africa has constitutionalised the right to fair labour practices and the question is whether this right is applicable to South African employees working in other countries, or to foreigners working in South Africa who originate from countries where this right is not protected. The answer to this question is to be found in the influence of the Constitution on the rules of private international law as applied by South African courts. It is evident from recent judgments of the Labour Court that the Court will readily assume jurisdiction and will furthermore readily hold that the proper law of the contract is South African law in order to protect the constitutional rights of employees involved in international employment contracts. Had the Labour Court held that the place of performance was still the decisive connecting factor, (as previously decided in most South African cases on this aspect the law of the other countries involved in the international employment relationship could have left employees in a worse position than under South African law. This possibility seems to be one of the important underlying reasons for the Labour Court’s willingness to assume jurisdiction and to hold that the proper law was in fact South African law. In the globalisation context the Labour Court has contributed to the advancement of constitutionalism by developing South Africa

  16. Understanding the effects of past flood events and perceived and estimated flood risks on individuals' voluntary flood insurance purchase behavior.

    Science.gov (United States)

    Shao, Wanyun; Xian, Siyuan; Lin, Ning; Kunreuther, Howard; Jackson, Nida; Goidel, Kirby

    2017-01-01

    Over the past several decades, the economic damage from flooding in the coastal areas has greatly increased due to rapid coastal development coupled with possible climate change impacts. One effective way to mitigate excessive economic losses from flooding is to purchase flood insurance. Only a minority of coastal residents however have taken this preventive measure. Using original survey data for all coastal counties of the United States Gulf Coast merged with contextual data, this study examines the effects of external influences and perceptions of flood-related risks on individuals' voluntary behaviors to purchase flood insurance. It is found that the estimated flood hazard conveyed through the U.S. Federal Emergency Management Agency's (FEMA's) flood maps, the intensities and consequences of past storms and flooding events, and perceived flood-related risks significantly affect individual's voluntary purchase of flood insurance. This behavior is also influenced by home ownership, trust in local government, education, and income. These findings have several important policy implications. First, FEMA's flood maps have been effective in conveying local flood risks to coastal residents, and correspondingly influencing their decisions to voluntarily seek flood insurance in the U.S. Gulf Coast. Flood maps therefore should be updated frequently to reflect timely and accurate information about flood hazards. Second, policy makers should design strategies to increase homeowners' trust in the local government, to better communicate flood risks with residents, to address the affordability issue for the low-income, and better inform less educated homeowners through various educational programs. Future studies should examine the voluntary flood insurance behavior across countries that are vulnerable to flooding. Copyright © 2016 Elsevier Ltd. All rights reserved.

  17. Assessing understanding of individual risk and symptoms of progressive multifocal leukoencephalopathy in patients prescribed natalizumab for multiple sclerosis.

    Science.gov (United States)

    Rath, Louise; Vijiaratnam, Nirosen; Skibina, Olga

    2017-02-01

    Natalizumab, a monoclonal antibody directed against α4 integrin, is a highly efficacious treatment commonly used in relapsing remitting multiple sclerosis. Natalizumab is associated with the potentially fatal, rare, demyelinating, opportunistic brain infection, progressive multifocal leukoencephalopathy (PML). Prognosis and disability from PML are determined by early diagnosis. Written tools are mandated in Australia and other prescribing countries with the aim to help patients understand the risks associated with treatment and ensure familiarity with the early symptoms of PML. We aimed to assess if these tools achieve such an outcome. A cross-sectional survey was conducted using a convenience sample of multiple sclerosis patients prescribed natalizumab presenting to the infusion centre at a major tertiary hospital. Patients were offered a multi-choice questionnaire to assess their knowledge on the treatment risks and surveillance requirements of their therapy. Three specific questions were highlighted by the researchers as crucial to patient understanding of PML and defined as basic knowledge. A total of 48 patients in our hospital was prescribed natalizumab; 37 responded. A total of 16 (43.2%) patients answered all three basic knowledge questions correctly. There was no difference in the ability to answer these questions based on length of treatment or co-ownership knowledge between patients with base knowledge and without. Natalizumab is associated with an increased risk of PML. Early detection and treatment of PML results in improved patient outcomes. Patient knowledge and co-partnership in the utilisation of PML risk tools is relevant in ensuring early detection. Our findings question the ability of currently sanctioned tools to inform patients of basic knowledge of PML and their risk of developing PML. A future study with a repetitive education approach and repeating the questionnaire at multiple time points would be of interest. © 2016 Royal Australasian

  18. Assessing the Understanding of Pharmaceutical Pictograms among Cultural Minorities: The Example of Hindu Individuals Communicating in European Portuguese.

    Science.gov (United States)

    Kanji, Lakhan; Xu, Sensen; Cavaco, Afonso

    2018-03-05

    One of the sources of poor health outcomes is the lack of compliance with the prescribed treatment plans, often due to communication barriers between healthcare professionals and patients. Pictograms are a form of communication that conveys meaning through its pictorial resemblance to a physical object or an action. Pharmaceutical pictograms are often associated with a better comprehension of treatment regimens, although their use is still subject to limitations. The main goal of this study was to examine the potential understanding of pharmaceutical pictograms by a cultural minority when providing patient information while comparing the effectiveness of two reference systems (United States Pharmacopeia USP and International Pharmacy Federation FIP) for this purpose. A self-administered questionnaire was developed comprising 30 pictograms, 15 selected from the United States Pharmacopeia Dispensing Information and the equivalent from the International Pharmaceutical Federation. The questionnaire comprised plain instructions, socio-demographic data, self-reported language fluency and pictogram labels in Portuguese presented to conveniently selected members of the Hindu community of Lisbon (Portugal) until reaching a quota of 50. Participants showed difficulties in understanding some pictograms, which was related to the self-reported reduced fluency in Portuguese. Overall, the interpretation of USP pictograms was better than FIP ones, as well as for pictograms composed of multiple images, presenting a negative reading, or when conveying information unrelated to medication instructions. Even using internationally validated pictograms, added care should be taken when community pharmacists use such communication resources with cultural minorities. It is important not to disregard other forms of patient communication and information, considering pictograms as a complement to other forms of patient counselling.

  19. Relationship between Self-Administered Cues and Rehabilitation Outcomes in Individuals with Aphasia: Understanding Individual Responsiveness to a Technology-Based Rehabilitation Program.

    Science.gov (United States)

    Des Roches, Carrie A; Mitko, Annette; Kiran, Swathi

    2017-01-01

    An advantage of rehabilitation administered on computers or tablets is that the tasks can be self-administered and the cueing required to complete the tasks can be monitored. Though there are many types of cueing, few studies have examined how participants' response to rehabilitation is influenced by self-administered cueing, which is cueing that is always available but the individual decides when and which cue to administer. In this study, participants received a tablet-based rehabilitation where the tasks were selfpaced and remotely monitored by a clinician. The results of the effectiveness of this study were published previously (Des Roches et al., 2015). The current study looks at the effect of cues on accuracy and rehabilitation outcomes. Fifty-one individuals with aphasia completed a 10-week program using Constant Therapy on an iPad targeted at improving language and cognitive deficits. Three questions were examined. The first examined the effect of cues on accuracy collapsed across time. Results showed a trend where the greater the cue use, the lower the accuracy, although some participants showed the opposite effect. This analysis divided participants into profiles based on cue use and accuracy. The second question examined how each profile differed in percent cue use and on standardized measures at baseline. Results showed that the four profiles were significantly different in frequency of cues and scores on WAB-R, CLQT, BNT, and ASHA-FACS, indicating that participants with lower scores on the standardized tests used a higher percentage of cues, which were not beneficial, while participants with higher scores on the standardized tests used a lower frequency of cues, which were beneficial. The third question examined how the relationship between cues and accuracy was affected by the course of treatment. Results showed that both more and less severe participants showed a decrease in cue use and an increase in accuracy over time, though more severe

  20. Creating Socionas : Building creative understanding of people's experiences in the early stages of new product development

    NARCIS (Netherlands)

    Postma, C.E.

    2012-01-01

    This work presents the research into Creating Socionas, a step-by-step approach to building creative understanding of user experience in the early stages of new product development (NPD). Creative understanding is the combination of a rich, cognitive and affective understanding of the other, and the

  1. Identifying and Understanding the Health Information Experiences and Preferences of Individuals With TBI, SCI, and Burn Injuries

    Directory of Open Access Journals (Sweden)

    Nathan T Coffey MPH

    2016-09-01

    Full Text Available Introduction: Traumatic brain injury, spinal cord injury, and burn injury can cause lifelong disability and changes in quality of life. In order to meet the challenges of postinjury life, various types of health information are needed. We sought to identify preferred sources of health information and services for persons with these injuries and discover how accessibility could be improved. Methods: Thirty-three persons with injury participated in semistructured interviews. Responses to interview questions were coded using NVivo. Results: Participants’ difficulties accessing health information varied by injury type and individually. The majority of respondents found information via the Internet and advocated its use when asked to describe their ideal health information system. Nearly all participants supported the development of a comprehensive care website. When searching for health information, participants sought doctor and support group networks, long-term health outcomes, and treatments specific to their injury. Conclusion: To optimize the quality of health information resources, Internet-based health-care platforms should add or highlight access points to connect patients to medical professionals and support networks while aggregating specialized, injury-specific research and treatment information.

  2. Effect of photoperiod on slow and fast developing individuals in aphidophagous ladybirds, Menochilus sexmaculatus and Propylea dissecta (Coleoptera: Coccinellidae).

    Science.gov (United States)

    Singh, Neha; Mishra, Geetanjali; Omkar

    2016-02-01

    The effects of environmental parameters on insect development have been studied extensively. But the reasons for 2 differential developmental rates within same cohort under varying environmental factors have not been explored. For the purpose, in this study the existence and stability of slow and fast development under 5 photoperiods (i.e., 8L: 16D, 10L : 14D, 12L : 12D, 14L : 10D and 16L : 8D; light and dark hours per day) and its effect on body mass and reproductive attributes in 2 aphidophagous ladybirds, Menochilus sexmaculatus (Fabricius) and Propylea dissecta (Mulsant) was examined on Aphis craccivora Koch at 27 ± 1 °C temperature. A clear bimodal (2 peaks, where the first peak represented the fast developing and the 2nd peak slow developing individuals) pattern of distribution at each photoperiod was found. The proportion of slow and fast developing individuals in a cohort differed with photoperiods. The slow developing individuals were more in numbers at 8L : 16D, in equal numbers at 14L : 10D and in less numbers at 16L: 8D, indicating that the variation in emergence was owing to exogenous cues influenced differential rates of mortality. Slow developing individuals had female biased sex ratio, higher longevity and lower body mass than fast developing individuals. Fast developing females laid higher numbers of eggs with higher egg viability than slow developing females. Study of such variations in development at different photoperiods is helpful to understand its role in the development of insects particularly ladybirds and permits the selection of fast developing bioagents for their use in biocontrol of pest species. © 2014 Institute of Zoology, Chinese Academy of Sciences.

  3. Preceptors' understanding and use of role modeling to develop the CanMEDS competencies in residents.

    Science.gov (United States)

    Côté, Luc; Laughrea, Patricia-Ann

    2014-06-01

    Role modeling by preceptors is a key strategy for training residents in the competencies defined within the CanMEDS conceptual framework. However, little is known about the extent to which preceptors are aware of the importance of role modeling or how they perceive and enact it in their daily interactions with residents. The purpose of this study was to describe how preceptors understand and use role modeling to develop CanMEDS competencies in residents. In 2010, the authors conducted a descriptive qualitative study with preceptors in medical, surgical, and laboratory specialties who supervised residents on a regular basis at the Université Laval Faculty of Medicine (Québec, Canada). Respondents participated in semistructured, individual interviews. An inductive thematic analysis of interview transcripts was conducted using triangulation. Most participants highlighted the importance of role modeling to support residents' development of the CanMEDS competencies, particularly communication, collaboration, and professionalism, which preceptors perceived as "less scientific" and the most difficult to teach. Although most participants reported using an implicit, unstructured role modeling process, some described more explicit strategies. Eight types of educational challenges in role modeling the CanMEDS competencies were identified, including encouraging reflective practice, understanding the competencies and their importance in one's specialty, and being aware of one's strengths and weaknesses as a clinical teacher. Preceptors are aware of the importance of role modeling competencies for residents, but many do so only implicitly. This study's findings are important for improving strategies for role modeling and for the professional development of preceptors.

  4. Development of a Case Formulation Model for Individuals Who Have Viewed, Distributed, and/or Shared Child Sexual Exploitation Material.

    Science.gov (United States)

    Merdian, Hannah L; Perkins, Derek E; Dustagheer, Elspeth; Glorney, Emily

    2018-01-01

    Increases in the number of arrests of individuals who download or distribute Child Sexual Exploitation Material (CSEM) have highlighted a need to further understand the offending pathways of this offender group. This article describes the development of an aetiological model specific to CSEM offending. Individuals who had viewed, distributed, and/or shared CSEM ( n = 20) were interviewed regarding their life and sexual history, relationships, substance use, offending details, and circumstances leading to their CSEM offending, resulting in seven superordinate themes: Developmental Context, Individual Propensities (risk-related and risk-protective) and Psychological Vulnerabilities, Personal Circumstances, Permission-Giving Thoughts, Internet Environment and Behaviour, Evaluation of Consequences for the Individual, and Desistance. These themes were combined into a case formulation tool specific for CSEM offending behaviour, with the aim of providing systematic guidance for assessment and treatment providers.

  5. Global gene expression profiling of individual human oocytes and embryos demonstrates heterogeneity in early development.

    Directory of Open Access Journals (Sweden)

    Lisa Shaw

    Full Text Available Early development in humans is characterised by low and variable embryonic viability, reflected in low fecundity and high rates of miscarriage, relative to other mammals. Data from assisted reproduction programmes provides additional evidence that this is largely mediated at the level of embryonic competence and is highly heterogeneous among embryos. Understanding the basis of this heterogeneity has important implications in a number of areas including: the regulation of early human development, disorders of pregnancy, assisted reproduction programmes, the long term health of children which may be programmed in early development, and the molecular basis of pluripotency in human stem cell populations. We have therefore investigated global gene expression profiles using polyAPCR amplification and microarray technology applied to individual human oocytes and 4-cell and blastocyst stage embryos. In order to explore the basis of any variability in detail, each developmental stage is replicated in triplicate. Our data show that although transcript profiles are highly stage-specific, within each stage they are relatively variable. We describe expression of a number of gene families and pathways including apoptosis, cell cycle and amino acid metabolism, which are variably expressed and may be reflective of embryonic developmental competence. Overall, our data suggest that heterogeneity in human embryo developmental competence is reflected in global transcript profiles, and that the vast majority of existing human embryo gene expression data based on pooled oocytes and embryos need to be reinterpreted.

  6. Children's Aural and Kinesthetic Understanding of Rhythm: Developing an Instructional Model

    Science.gov (United States)

    Foley, Adam D.

    2013-01-01

    The purpose of this study was to develop a deeper understanding of aural and kinesthetic rhythm skill development in elementary school-age children. In this study, I examined my curriculum model for rhythm understanding, which included creating and implementing assessments of movement skills in meter and rhythm. The research questions were: 1.…

  7. A Cultural-Historical Model to Understand and Facilitate Children's Development

    Science.gov (United States)

    Wong, Pui Ling

    2015-01-01

    Parents and educators strive to help their children to develop optimally. Given the diversity of values and practices among dynamic modern populations it is important to understand all the dimensions that affect the development of children in their communities. A cultural-historical lens facilitates such a holistic understanding. Taking this lens,…

  8. Premorbid adjustment in individuals at ultra-high risk for developing psychosis

    DEFF Research Database (Denmark)

    Dannevang, Anders; Randers, Lasse; Gondan, Matthias

    2017-01-01

    Objective: Deterioration in premorbid adjustment is related to ultra-high risk (UHR) individuals developing psychosis, but it has not been examined how UHR individuals’ development differs compared to healthy controls. This study investigates differences in premorbid adjustment between UHR...

  9. 34 CFR 607.11 - What must be included in individual development grant applications?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What must be included in individual development grant applications? 607.11 Section 607.11 Education Regulations of the Offices of the Department of Education... Does an Institution Apply for a Grant? § 607.11 What must be included in individual development grant...

  10. Cultural Narratives: Developing a Three-Dimensional Learning Community through Braided Understanding

    Science.gov (United States)

    Heck, Marsha L.

    2004-01-01

    Paula Underwood's "Learning Stories" braid together body, mind, and spirit to enable understanding that does not easily unravel. They tell of relationships among individual and community learning that parallel other ancient and contemporary ideas about learning in caring communities. Underwood's tradition considers learning sacred; everyone's…

  11. 34 CFR 606.11 - What must be included in individual development grant applications?

    Science.gov (United States)

    2010-07-01

    ... development grant applications? In addition to the information needed by the Secretary to determine whether... application for a development grant must include— (a) The institution's comprehensive development plan; (b) A... 34 Education 3 2010-07-01 2010-07-01 false What must be included in individual development grant...

  12. Looking Back, Looking Forward, Living in the Moment: Understanding the Individual Temporal Perspectives of Secondary School EFL Learners

    Science.gov (United States)

    Begic, Ines; Mercer, Sarah

    2017-01-01

    Every individual has a different perspective on time, known as "temporal perspective". A person's orientation and attitude towards time can have a profound effect on their behaviour and motivation. In Second Language Acquisition, a variety of work has considered learners and their behaviours from various temporal perspectives. However,…

  13. Towards an Understanding of Enabling Process Knowing in Global Software Development: A Case Study

    DEFF Research Database (Denmark)

    Zahedi, Mansooreh; Babar, Muhammad Ali

    2014-01-01

    Shared understanding of Software Engineering (SE) processes, that we call process knowing, is required for effective communication and coordination and communication within a team in order to improve team performance. SE Process knowledge can include roles, responsibilities and flow of information...... over a project lifecycle. Developing and sustaining process knowledge can be more challenging in Global Software Development (GSD). GSD distances can limit the ability of a team to develop a common understanding of processes. Anecdotes of the problems caused by lack of common understanding of processes...

  14. Subject- and Experience-Bound Differences in Teachers' Conceptual Understanding of Sustainable Development

    Science.gov (United States)

    Borg, C.; Gericke, N.; Höglund, H.-O.; Bergman, E.

    2014-01-01

    This article describes the results of a nationwide questionnaire study of 3229 Swedish upper secondary school teachers' conceptual understanding of sustainable development in relation to their subject discipline and teaching experience. Previous research has shown that teachers have difficulties understanding the complex concept of sustainable…

  15. Developing Critical Understanding in HRM Students: Using Innovative Teaching Methods to Encourage Deep Approaches to Study

    Science.gov (United States)

    Butler, Michael J. R.; Reddy, Peter

    2010-01-01

    Purpose: This paper aims to focus on developing critical understanding in human resource management (HRM) students in Aston Business School, UK. The paper reveals that innovative teaching methods encourage deep approaches to study, an indicator of students reaching their own understanding of material and ideas. This improves student employability…

  16. Educational Cooperation between Thailand and Cambodia: Outcomes on Human Development, International Understanding and Future Prospect

    Science.gov (United States)

    Kijtorntham, Wichuda; Ruangdej, Phumjit; Saisuwan, Chatchanog

    2015-01-01

    Thailand and Cambodia set up educational cooperation since 1996, before signed a Memorandum of Understanding on Cooperation in the Promotion of Education in 2003. This research aimed to investigate outcomes of educational cooperation projects on Cambodia human development and international understanding, process of participatory learning and…

  17. Developing Intercultural Understanding for Study Abroad: Students' and Teachers' Perspectives on Pre-Departure Intercultural Learning

    Science.gov (United States)

    Holmes, P.; Bavieri, L.; Ganassin, S.

    2015-01-01

    This study reports on students' and teachers' perspectives on a programme designed to develop Erasmus students' intercultural understanding prior to going abroad. We aimed to understand how students and their teachers perceived pre-departure materials in promoting their awareness of key concepts related to interculturality (e.g., essentialism,…

  18. Modeling Systematicity and Individuality in Nonlinear Second Language Development: The Case of English Grammatical Morphemes

    Science.gov (United States)

    Murakami, Akira

    2016-01-01

    This article introduces two sophisticated statistical modeling techniques that allow researchers to analyze systematicity, individual variation, and nonlinearity in second language (L2) development. Generalized linear mixed-effects models can be used to quantify individual variation and examine systematic effects simultaneously, and generalized…

  19. Exploring the relation between individual moral antecedents and entrepreneurial opportunity recognition for sustainable development

    NARCIS (Netherlands)

    Ploum, Lisa; Blok, Vincent; Lans, Thomas; Omta, Onno

    2018-01-01

    When dealing with complex value-driven problems such as sustainable development, individuals need to have values and norms that go beyond the appropriation of tangible business outcomes for themselves. This raises the question of the role played by individual moral antecedents in the entrepreneurial

  20. Individual Differences in the Extent and Development of Aggressive Cognitive-Associative Networks.

    Science.gov (United States)

    Bushman, Brad J.

    1996-01-01

    Extends L. Berkowitz's neoassociationist aggression model by considering the role of personality variables. Experiment one tested the hypothesis that high-trait-aggressive individuals have more developed aggressive cognitive-associative networks than low-trait-aggressive individuals. In experiment two, participants rated the stimulus words used in…

  1. Factors contributing to the longitudinal development of social participation in individuals with cerebral palsy

    NARCIS (Netherlands)

    Tan, Siok Swan; van der Slot, Wilma M A; Ketelaar, Marjolijn; Becher, Jules G.; Dallmeijer, Annet J.; Smits, Dirk Wouter; Roebroeck, Marij E.

    2016-01-01

    Aims We aimed to determine factors associated with the longitudinal development of social participation in a Dutch population of individuals with Cerebral Palsy (CP) aged 1–24 years. Methods and procedures For this multicentre prospective longitudinal study, 424 individuals with CP aged 1–24 years

  2. The Effect of Literature on Personality Development of Individuals Using Some Variables

    Science.gov (United States)

    Tatlilioglu, Kasim

    2017-01-01

    The aim of this work is to investigate whether literature has effect on the personality development of individuals or not. This works aims to provide answers to the following research questions: "Does literature have effect on individuals' general harmony level, their social cohesion levels, personal harmony level, self-actualization level,…

  3. Understanding the design research process: The evolution of a professional development program in Indian slums

    NARCIS (Netherlands)

    McKenney, Susan; Raval, Harini; Pieters, Jules

    2011-01-01

    McKenney, S., Raval, H., & Pieters, J. (2011, 8-12 April). Understanding the design research process: The evolution of a professional development program in Indian slums. Presentation at AERA annual meeting, New Orleans.

  4. Understanding the design research process: The evolution of a professional development program in Indian slums

    OpenAIRE

    McKenney, Susan; Raval, Harini; Pieters, Jules

    2011-01-01

    McKenney, S., Raval, H., & Pieters, J. (2011, 8-12 April). Understanding the design research process: The evolution of a professional development program in Indian slums. Paper presentation at AERA annual meeting, New Orleans.

  5. Understanding the design research process: The evolution of a professional development program in Indian slums

    NARCIS (Netherlands)

    McKenney, Susan; Raval, Harini; Pieters, Jules

    2012-01-01

    McKenney, S., Raval, H., & Pieters, J. (2011, 8-12 April). Understanding the design research process: The evolution of a professional development program in Indian slums. Paper presentation at AERA annual meeting, New Orleans.

  6. Postscript: Researching Stochastic Understanding--The Place of a Developing Research Field in PME.

    Science.gov (United States)

    Truran, John

    2001-01-01

    Traces some aspects of the development of stochastics education and research to provide a background for understanding the place of the Psychology of Mathematics Education (PME) Stochastics Group in the research process. (MM)

  7. The Relationship between Student Leaders' Constructive Development, Their Leadership Identity, and Their Understanding of Leadership

    Science.gov (United States)

    Sessa, Valerie I.; Ploskonka, Jillian; Alvarez, Elphys L.; Dourdis, Steven; Dixon, Christopher; Bragger, Jennifer D.

    2016-01-01

    The purpose of our research was to use Day, Harrison, and Halpin's, (2009) theory of leadership development as a premise to investigate how students' constructive development is related to their leader identity development and understanding of leadership. Baxter Magolda's Model of Epistemological Reflection (MER, 1988, 2001) was used to understand…

  8. Understanding by Design (UbD) in EFL Teaching: Teachers' Professional Development and Students' Achievement

    Science.gov (United States)

    Yurtseven, Nihal; Altun, Sertel

    2017-01-01

    Concepts such as teachers' professional development and students' achievement act as the driving force for the development of each in a causal relationship in EFL teaching, as in many other disciplines. The purpose of this study is to investigate the change Understanding by Design (UbD) made on teachers' professional development and students'…

  9. Understanding the Conceptual Development Phase of Applied Theory-Building Research: A Grounded Approach

    Science.gov (United States)

    Storberg-Walker, Julia

    2007-01-01

    This article presents a provisional grounded theory of conceptual development for applied theory-building research. The theory described here extends the understanding of the components of conceptual development and provides generalized relations among the components. The conceptual development phase of theory-building research has been widely…

  10. Role of Sports in the Development of an Individual and Role of Psychology in Sports

    OpenAIRE

    Rakesh Ghildiyal

    2015-01-01

    Sports helps an individual much more than in the physical aspects alone. It builds character, teaches and develops strategic thinking, analytical thinking, leadership skills, goal setting and risk taking, just to name a few.

  11. Communicative foreign language education for development of individual in different cultures

    International Nuclear Information System (INIS)

    Solovieva, T.S.

    2000-01-01

    In this article the development of the individual in the sphere of nuclear industry and technology is considered on the example of Obninsk Institute of Nuclear Power Engineering as the model of totality of all these factors. (authors)

  12. Dynamic use of geoscience information to develop scientific understanding for a nuclear waste repository

    International Nuclear Information System (INIS)

    Cook, N.G.W.; Tsang, C.F.

    1990-01-01

    This paper discusses the development and safety evaluation of a nuclear waste geologic repository. Scientific understanding dependent upon information from a number of geoscience disciplines is described. A discussion is given on the dynamic use of the information through the different stages. The authors point out the need for abstracting, deriving and updating a quantitative spatial and process model (QSPM) to develop a scientific understanding of site responses as a crucial element in the dynamic procedure

  13. DIGCOMP: a Framework for Developing and Understanding Digital Competence in Europe

    OpenAIRE

    FERRARI Anusca; BRECKO BARBARA; PUNIE Yves

    2014-01-01

    The paper describes the digital competence framework developed by EC JRC IPTS on behalf of DG Education and Culture with the overall aim to contribute to the better understanding and development of digital competence in Europe. Digital competence is one of the eight key competences for lifelong learning and is essential for participation in our increasingly digitalised society. It is therefore necessary to understand and define what digital competence is and consists of. The paper discusses v...

  14. Understanding the social effects of emotion regulation: the mediating role of authenticity for individual differences in suppression.

    Science.gov (United States)

    English, Tammy; John, Oliver P

    2013-04-01

    Individuals differ in the strategies they use to regulate their emotions (e.g., suppression, reappraisal), and these regulatory strategies can differentially influence social outcomes. However, the mechanisms underlying these social effects remain to be specified. We examined one potential mediator that arises directly from emotion-regulatory effort (expression of positive emotion), and another mediator that does not involve emotion processes per se, but instead results from the link between regulation and self-processes (subjective inauthenticity). Across three studies, only inauthenticity mediated the link between habitual use of suppression and poor social functioning (lower relationship satisfaction, lower social support). These findings replicated across individuals socialized in Western and East Asian cultural contexts, younger and older adults, when predicting social functioning concurrently and a decade later, and even when broader adjustment was controlled. Thus, the social costs of suppression do not seem to be due to reduced positive emotion expression but rather the incongruence between inner-self and outer-behavior. Reappraisal was not consistently related to social functioning. Implications of these findings for emotion processes, self processes, and interpersonal relationships are discussed. PsycINFO Database Record (c) 2013 APA, all rights reserved.

  15. Proposal of a generics individual competence development plan lined up to enterprise strategy

    Directory of Open Access Journals (Sweden)

    Edson Bündchen

    2005-01-01

    Full Text Available This article describes the results of a study that propose a Competencies Development Plan for an Agency of a traditional Brazilian financial institution from the identification of generic individual competencies. The study disclosed that the Agency needs to develop six competencies: communication, products and services, negotiation, internal self-development, internal processes and teamwork. The research results, in relation to the domain level, denote to a technics competence priorization. The study suggests a development plan orientated for the search of significant improvement in employees perceptions in relation to generic individuals competencies seeking to help the enterprise in strategy establishment.

  16. THE PSYCHODIAGNOSTICS OF THE EMOTIONAL INTELLIGENCE DEVELOPMENT OF INDIVIDUALS AT THE SENIOR SCHOOL AGE

    Directory of Open Access Journals (Sweden)

    I. V. Opanasyuk

    2015-03-01

    Full Text Available Background. The article deals with the phenomenon of “emotional intelligence” and its characteristic features at the senior school age. It is proved that the emotional intelligence enables senior pupils to reduce the impact of negative feelings with the help of the control over the situation and their emotions. The topicality of the problem is determined by the fact that the emotional intelligence is one of the prerequisites to the formation of the senior pupils’ personality, their ability to ensure and regulate the acquired experience, as well as the ability of self-identi?cation. Objective. The purpose of the study is to determine the level of the senior pupils’ emotional intelligence development, as well as to analyze the nature of the interrelation of its components. The set aim presupposes the ful?llment of the following tasks: 1 to analyze the content characteristic feature of the phenomenon of “emotional intelligence” and the levels of its development among the senior pupils; 2 to carry out the diagnostics of the development of the senior pupils’ emotional intelligence; 3 to identify the relationships between the emotional intelligence and its components on the basis of the empirical researches. Method. The research tasks have determined the sample of 420 pupils (15-17 years old representing various schools of the Ivano-Frankivsk region. The diagnostics of emotional barriers in interpersonal communication (V.V. Boyko; the diagnostics of emotional intelligence (N. Hall; the diagnostics of the emotional orientation of the individual (B.I. Dodonov; the emotional intelligence questionnaire “EmIn” (D.V. Lyusin. The mathematical processing of the above-mentioned test methods was conducted with the help of the correlation and factor analysis. Results. The research identi?es signi?cant relationships between the emotional intelligence components. The emotional intelligence correlates with understanding one’s own and others

  17. Measuring and Comparing Academic Language Development and Conceptual Understanding via Science Notebooks

    Science.gov (United States)

    Huerta, Margarita; Tong, Fuhui; Irby, Beverly J.; Lara-Alecio, Rafael

    2016-01-01

    The authors of this quantitative study measured and compared the academic language development and conceptual understanding of fifth-grade economically disadvantaged English language learners (ELL), former ELLs, and native English-speaking (ES) students as reflected in their science notebook scores. Using an instrument they developed, the authors…

  18. Children's Perspectives as "Touch Downs" in Time: Assessing and Developing Children's Understanding Simultaneously

    Science.gov (United States)

    Samuelsson, Ingrid Pramling; Pramling, Niklas

    2009-01-01

    In this article, getting access to children's perspectives is presented as a prerequisite for assessing as well as developing children's understanding. Children's perspectives are analysed through examples taken from three domains of knowledge: music, mathematics and nature. The issues of assessing and developing children's knowledge are discussed…

  19. Understanding the Relationship between Social Cognition and Word Difficulty. A Language Based Analysis of Individuals with Autism Spectrum Disorder.

    Science.gov (United States)

    Aramaki, E; Shikata, S; Miyabe, M; Usuda, Y; Asada, K; Ayaya, S; Kumagaya, S

    2015-01-01

    Few quantitative studies have been conducted on the relationship between society and its languages. Individuals with autistic spectrum disorder (ASD) are known to experience social hardships, and a wide range of clinical information about their quality of life has been provided through numerous narrative analyses. However, the narratives of ASD patients have thus far been examined mainly through qualitative approaches. In this study, we analyzed adults with ASD to quantitatively examine the relationship between language abilities and ASD severity scores. We generated phonetic transcriptions of speeches by 16 ASD adults at an ASD workshop, and divided the participants into 2 groups according to their Social Responsiveness Scale(TM), 2nd Edition (SRS(TM)-2) scores (where higher scores represent more severe ASD): Group A comprised high-scoring ASD adults (SRS(TM)-2 score: ≥ 76) and Group B comprised low- and intermediate-scoring ASD adults (SRS(TM)-2 score: relationships between the language ability scores and ASD severity scores were compared. Group A showed a marginally negative correlation with the level of Japanese word difficulty (p applications of these findings may be available in the near future, and there is a need for further detailed study on language metrics designed for ASD adults.

  20. Teaching Teaching & Understanding Understanding

    DEFF Research Database (Denmark)

    2006-01-01

    "Teaching Teaching & Understanding Understanding" is a 19-minute award-winning short-film about teaching at university and higher-level educational institutions. It is based on the "Constructive Alignment" theory developed by Prof. John Biggs. The film delivers a foundation for understanding what...

  1. Genetic programming as alternative for predicting development effort of individual software projects.

    Directory of Open Access Journals (Sweden)

    Arturo Chavoya

    Full Text Available Statistical and genetic programming techniques have been used to predict the software development effort of large software projects. In this paper, a genetic programming model was used for predicting the effort required in individually developed projects. Accuracy obtained from a genetic programming model was compared against one generated from the application of a statistical regression model. A sample of 219 projects developed by 71 practitioners was used for generating the two models, whereas another sample of 130 projects developed by 38 practitioners was used for validating them. The models used two kinds of lines of code as well as programming language experience as independent variables. Accuracy results from the model obtained with genetic programming suggest that it could be used to predict the software development effort of individual projects when these projects have been developed in a disciplined manner within a development-controlled environment.

  2. Development of a Short Form of the Boston Naming Test for Individuals with Aphasia

    Science.gov (United States)

    del Toro, Christina M.; Bislick, Lauren P.; Comer, Matthew; Velozo, Craig; Romero, Sergio; Rothi, Leslie J. Gonzalez; Kendall, Diane L.

    2011-01-01

    Purpose: The purpose of this study was to develop a short form of the Boston Naming Test (BNT; Kaplan, Goodglass, & Weintraub, 2001) for individuals with aphasia and compare it with 2 existing short forms originally analyzed with responses from people with dementia and neurologically healthy adults. Method: Development of the new BNT-Aphasia Short…

  3. Individual Differences in Self-Efficacy Development: The Effects of Goal Orientation and Affectivity

    Science.gov (United States)

    Gerhardt, Megan W.; Brown, Kenneth G.

    2006-01-01

    This study examined the moderating role of the individual differences of goal orientation and affectivity on self-efficacy development. Consistent with hypotheses, results indicate that both positive and negative affectivity moderate the impact of an enactive mastery training program on efficacy development, with those higher in positive…

  4. Development of Self-Management in an Individual with Mental Retardation: A Qualitative Case Study.

    Science.gov (United States)

    Richardson, Gail M.; And Others

    1996-01-01

    Ethnographic methodology was used to explore the development of self-management skills in an 18-year-old woman with Down Syndrome. Triangulation of data types and the constant comparative method of data analysis were employed. Outcomes suggested the individual's family culture had a large impact on development of self-monitoring and that early and…

  5. Individualized early prediction of familial risk of dyslexia : A study of infant vocabulary development

    NARCIS (Netherlands)

    Chen, Ao; Wijnen, Frank; Koster, Charlotte; Schnack, Hugo

    2017-01-01

    We examined early vocabulary development in children at familial risk (FR) of dyslexia and typically developing (TD) children between 17 and 35 months of age. We trained a support vector machine to classify TD and FR using these vocabulary data at the individual level. The Dutch version of the

  6. Understanding Resilience

    Directory of Open Access Journals (Sweden)

    Gang eWu

    2013-02-01

    Full Text Available Resilience is the ability to adapt successfully in the face of stress and adversity. Stressful life events, trauma and chronic adversity can have a substantial impact on brain function and structure, and can result in the development of PTSD, depression and other psychiatric disorders. However, most individuals do not develop such illnesses after experiencing stressful life events, and are thus thought to be resilient. Resilience as successful adaptation relies on effective responses to environmental challenges and ultimate resistance to the deleterious effects of stress, therefore a greater understanding of the factors that promote such effects is of great relevance. This review focuses on recent findings regarding genetic, epigenetic, developmental, psychosocial and neurochemical factors that are considered essential contributors to the development of resilience. Neural circuits and pathways involved in mediating resilience are also discussed. The growing understanding of resilience factors will hopefully lead to the development of new pharmacological and psychological interventions for enhancing resilience and mitigating the untoward consequences.

  7. Student understanding development in chemistry concepts through constructivist-informed laboratory and science camp process in secondary school

    Science.gov (United States)

    Pathommapas, Nookorn

    2018-01-01

    Science Camp for Chemistry Concepts was the project which designed to provide local students with opportunities to apply chemistry concepts and thereby developing their 21st century skills. The three study purposes were 1) to construct and develop chemistry stations for encouraging students' understandings in chemistry concepts based on constructivist-informed laboratory, 2) to compare students' understandings in chemistry concepts before and after using chemistry learning stations, and 3) to study students' satisfactions of using their 21st century skills in science camp activities. The research samples were 67 students who attended the 1-day science camp. They were levels 10 to 11 students in SumsaoPittayakarn School, UdonThani Province, Thailand. Four constructivist-informed laboratory stations of chemistry concepts were designed for each group. Each station consisted of a chemistry scenario, a question, answers in tier 1 and supporting reasons in tier 2, and 4 sets of experimental instruments. Four to five-member subgroups of four student groups parallel participated in laboratory station for an hour in each station. Student activities in each station concluded of individual pretest, group prediction, experimental design, testing out and collection data, interpreting the results, group conclusion, and individual post-test. Data collection was done by station mentors using two-tier multiple choice questions, students' written work and interviews. Data triangulation was used for interpreting and confirming students' understandings of chemistry concepts which divided into five levels, Sound Understanding (SU), Partial Understanding (PU), Specific Misconception (SM), No Understanding (NU) and No Response (NR), before and after collaborating at each station. The study results found the following: 1) four constructivist-laboratory stations were successfully designed and used to investigate student' understandings in chemistry concepts via collaborative workshop of

  8. Development of the national register of radiation workers: subsystem for individual monitoring of external exposure

    International Nuclear Information System (INIS)

    Yu Haitao; Niu Haowei; Sun Quanfu; Fu Yinghua; Fan Yaohua; Yue Baorong

    2010-01-01

    Objective: To develop a national registry and reporting system of individual monitoring for workers occupationally exposed to ionizing radiation. Methods: In accordance with the relevant law, regulations, standards and the current health supervision practice for radiation workers in China, to ensure more effective collection of information on individual monitoring from all levels of service providers across the country and an easy query and analysis of the collected information for both service providers and administrative institutions, the register consisted of an offline-system and a web-based information system. The off-line system consisted of 8 tables, which could easily make annual and period monitoring reports, and upload individual monitoring data in compressed and encrypted format. Web-based system consisted of 6 modules, could easily make S customized tabulations of monitoring data and show 2 trend figures. SSLVPN secure remote access was used in the system. Arranged by the Ministry of Health, training courses provided to all individual monitoring service providers and provincial administrative institutions. Results: A new and individual-based national register and reporting system of individual monitoring for workers occupationally exposed to ionizing radiation was successfully developed, and would be officially run soon. Conclusions: The establishment and running of the register would be great improvement on the national radiological health reports and produce a far-reaching impact on the individual monitoring in China. (authors)

  9. Communicative foreign language education for development of individual in different cultures

    International Nuclear Information System (INIS)

    Solovieva, T.S.

    2001-01-01

    Social changes in community and also in principles of education, psychology of activity and philosophy lead to changes in views on human as a whole, on place of individual in society and on definition of individual itself, on essence of education and on foreign language as business communication mean and separate discipline. In this article the development of the individual in the sphere of nuclear industry and technology is considered on the example of Obninsk Institute of Nuclear Power Engineering as the model of totality of all these factors. (author)

  10. Individual-level outcomes from a national clinical leadership development programme.

    Science.gov (United States)

    Patton, Declan; Fealy, Gerard; McNamara, Martin; Casey, Mary; Connor, Tom O; Doyle, Louise; Quinlan, Christina

    2013-08-01

    A national clinical leadership development programme was instituted for Irish nurses and midwives in 2010. Incorporating a development framework and leadership pathway and a range of bespoke interventions for leadership development, including workshops, action-learning sets, mentoring and coaching, the programme was introduced at seven pilot sites in the second half of 2011. The programme pilot was evaluated with reference to structure, process and outcomes elements, including individual-level programme outcomes. Evaluation data were generated through focus groups and group interviews, individual interviews and written submissions. The data provided evidence of nurses' and midwives' clinical leadership development through self and observer-reported behaviours and dispositions including accounts of how the programme participants developed and displayed particular clinical leadership competencies. A key strength of the new programme was that it involved interventions that focussed on specific leadership competencies to be developed within the practice context.

  11. Disasters and development: Part 2: understanding and exploiting disaster-development linkages.

    Science.gov (United States)

    Stephenson, Rob S; DuFrane, Charles

    2002-01-01

    Disasters can impede the effectiveness of development resource allocation. The damage sustained from an event can be classified into four categories: (1) Loss of resources; (2) Interruption of programs and switching of crucial resources to other, shorter-term needs; (3) Negative impacts upon investment climates; and/or (4) Disruption of the non-formal sector (local businesses). Disasters have a particularly destructive economic impact in areas in which there are few alternatives for assets that are destroyed or in areas in which the resources already are at critical levels. Development processes can both increase and/or decrease the vulnerability of a society to hazards. There are dearly established linkages between poverty, marginalization, over-population, and vulnerability. To a large extent, vulnerability derives from poverty. The poor are more likely to live in vulnerable areas (slopes prone to landslides, flood plains, marginal agricultural land), have difficulty accessing education and information, have fewer assets to invest in resources to reduce vulnerability, and are more prone to become malnourished and have chronic illnesses that predispose them to injury and death. Development may be associated with the production of new hazards accepted by a society because the perceived benefits of the development project far exceed the relative risk associated with the project. Therefore, risk assessments must be part of any program planning and evaluation. Training and education are of critical importance in preventing increased vulnerability as a result of development strategies. Development also can progress in a manner that will result in mitigation of the impacts of an event on a given society (increase absorbing capacity and/or buffering capacity, elimination of hazards or the risk of them producing a disaster). Such mitigation measures can be either structural or nonstructural. There exists a wide range of options for incorporating mitigation measures in

  12. Increased susceptibility of blood type O individuals to develop anemia in Plasmodium vivax infection.

    Science.gov (United States)

    Resende, Sarah Stela; Milagres, Vanessa Gonçalves; Chaves, Daniel Gonçalves; Fontes, Cor Jesus Fernandes; Carvalho, Luzia Helena; Sousa, Tais Nobrega; Brito, Cristiana Ferreira Alves de

    2017-06-01

    Plasmodium vivax has been reported to cause severe malaria, and one of the main resulting complications is anemia. Considering that P. vivax infects only young erythrocytes, anemia has been associated with the destruction of infected and non-infected erythrocytes. However, few studies have focused on understanding the relationship between the pathogenesis of P. vivax malaria and human genetic polymorphisms. Although ABO groups seem to influence the outcome of Plasmodium falciparum malaria, the association between P. vivax and ABO blood groups has been minimally investigated. Thus, we investigate the correlation between ABO blood groups and anemia induced by P. vivax infection. Five single nucleotide polymorphisms at the ABO gene were genotyped by PCR-RFLP and Real-Time PCR in P. vivax-infected subjects. The ABO blood types were associated with the hematological data of the patients. Our main finding was that type O infected-individuals showed lower levels of hemoglobin and hematocrit compared to type A-infected individuals. The correlation between ABO blood groups and hemoglobin levels remained significant when a multiple linear regression was applied with the possible confounding effects of clinical-epidemiologic variables taken into account. The finding that type O individuals have a higher frequency of anemia is a first step to understand the mechanisms involved in malaria anemia, which could be associated to increased destruction of type O erythrocytes. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Dynamic use of geoscience information to develop scientific understanding for a nuclear waste repository

    International Nuclear Information System (INIS)

    Cook, N.G.W.; Tsang, C.F.

    1990-01-01

    The development and safety evaluation of a nuclear waste geologic repository require a proper scientific understanding of the site response. Such scientific understanding depends on information from a number of geoscience disciplines, including geology, geophysics, geochemistry, geomechanics and hydrogeology. The information comes in four stages: (1) general regional survey data base, (2) surface-based testing, (3) exploratory shaft testing, and (4) repository construction and evaluation. A discussion is given on the dynamic use of the information through the different stages. We point out the need for abstracting, deriving and updating a quantitative spatial and process model (QSPM) to develop a scientific understanding of site responses as a crucial element in the dynamic procedure. 2 figs

  14. Understanding Emerging Impacts and Requirements Related to Utility-Scale Solar Development

    Energy Technology Data Exchange (ETDEWEB)

    Hartmann, Heidi M. [Argonne National Lab. (ANL), Argonne, IL (United States); Grippo, Mark A. [Argonne National Lab. (ANL), Argonne, IL (United States); Heath, Garvin A. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Macknick, Jordan [National Renewable Energy Lab. (NREL), Golden, CO (United States); Smith, Karen P. [Argonne National Lab. (ANL), Argonne, IL (United States); Sullivan, Robert G. [Argonne National Lab. (ANL), Argonne, IL (United States); Walston, Leroy J. [Argonne National Lab. (ANL), Argonne, IL (United States); Wescott, Konstance L. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2016-09-01

    Utility-scale solar energy plays an important role in the nation’s strategy to address climate change threats through increased deployment of renewable energy technologies, and both the federal government and individual states have established specific goals for increased solar energy development. In order to achieve these goals, much attention is paid to making utility-scale solar energy cost-competitive with other conventional energy sources, while concurrently conducting solar development in an environmentally sound manner.

  15. Describing Pre-Service Teachers' Developing Understanding of Elementary Number Theory Topics

    Science.gov (United States)

    Feldman, Ziv

    2012-01-01

    Although elementary number theory topics are closely linked to foundational topics in number and operations and are prevalent in elementary and middle grades mathematics curricula, little is currently known about how students and teachers make sense of them. This study investigated pre-service elementary teachers' developing understanding of…

  16. Students' Perceptions and Development of Conceptual Understanding Regarding Trigonometry and Trigonometric Function

    Science.gov (United States)

    Cetin, Omer Faruk

    2015-01-01

    This study aims to analyse university level mathematics education students' perceptions on conceptual understanding of trigonometry and trigonometric functions and their content development of these concepts. A case study was conducted with 90 freshman students of Elementary Mathematics Department. The data were gathered via a scale; they included…

  17. A Design Study to Develop Young Children's Understanding of Multiplication and Division

    Science.gov (United States)

    Bicknell, Brenda; Young-Loveridge, Jenny; Nguyen, Nhung

    2016-01-01

    This design study investigated the use of multiplication and division problems to help 5-year-old children develop an early understanding of multiplication and division. One teacher and her class of 15 5-year-old children were involved in a collaborative partnership with the researchers. The design study was conducted over two 4-week periods in…

  18. Developing Essential Understanding of Functions for Teaching Mathematics in Grades 9-12

    Science.gov (United States)

    Lloyd, Gwendolyn; Beckmann, Sybilla; Zbiek, Rose Mary; Cooney, Thomas

    2010-01-01

    Are sequences functions? What can't the popular "vertical line test" be applied in some cases to determine if a relation is a function? How does the idea of rate of change connect with simpler ideas about proportionality as well as more advanced topics in calculus? Helping high school students develop a robust understanding of functions requires…

  19. Developing Pre-Service Teachers' Noticing of Students' Understanding of the Derivative Concept

    Science.gov (United States)

    Sánchez-Matamoros, Gloria; Fernández, Ceneida; Llinares, Salvador

    2015-01-01

    This research study examines the development of the ability of pre-service teachers to notice signs of students' understanding of the derivative concept. It analyses preservice teachers' interpretations of written solutions to problems involving the derivative concept before and after participating in a teacher training module. The results…

  20. Development of a Student-Centered Instrument to Assess Middle School Students' Conceptual Understanding of Sound

    Science.gov (United States)

    Eshach, Haim

    2014-01-01

    This article describes the development and field test of the Sound Concept Inventory Instrument (SCII), designed to measure middle school students' concepts of sound. The instrument was designed based on known students' difficulties in understanding sound and the history of science related to sound and focuses on two main aspects of sound: sound…

  1. Nationally Appropriate Mitigation Action: Understanding the MRV framework for developing countries

    DEFF Research Database (Denmark)

    Sharma, Sudhir

    The objective of the publication is to enhance the knowledge of the policymakers and decision makers in developing countries on MRV systems,including requirement of operationalizing such a system. The paper is also aimed at increasing the understanding of MRV aspects among sectoral experts and de...

  2. Connecting Earth Systems: Developing Holistic Understanding through the Earth-System-Science Model

    Science.gov (United States)

    Gagnon, Valoree; Bradway, Heather

    2012-01-01

    For many years, Earth science concepts have been taught as thematic units with lessons in nice, neat chapter packages complete with labs and notes. But compartmentalized Earth science no longer exists, and implementing teaching methods that support student development of holistic understandings can be a time-consuming and difficult task. While…

  3. Reflection for learning: understanding the value of reflective writing for information literacy development

    OpenAIRE

    McKinney, P.A.; Sen, B.A.

    2012-01-01

    Reflective writing has long been acknowledged as an important aspect of personal and professional development. There is increasing evidence of the use of reflective writing assessments and activities in the context of information literacy education, particular in Higher Education. Writing reflectively can help students to understand their own information literacy development and engage in deeper learning. Students on an undergraduate Business Intelligence module at the University of Sheffield...

  4. Strategies to improve HIV treatment adherence in developed countries: clinical management at the individual level.

    Science.gov (United States)

    Enriquez, Maithe; McKinsey, David S

    2011-01-01

    REMARKABLE ADVANCES IN THE TREATMENT OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) DISEASE HAVE BEEN BLUNTED BY WIDESPREAD SUBOPTIMAL ADHERENCE (IE, NONADHERENCE), WHICH HAS EMERGED AS A MAJOR BARRIER TO ACHIEVING THE PRIMARY GOAL OF ANTIRETROVIRAL (ARV) THERAPY: suppression of HIV viral load. Nonsuppressed HIV viral load is associated with drug resistance, increased morbidity and mortality, and a higher risk of person-to-person HIV transmission. For HIV-infected individuals who are failing HIV treatment due to nonadherence, becoming adherent is a life-saving behavior change. However, overcoming nonadherence is one of the most daunting challenges in the successful management of HIV disease. The purpose of this paper is to provide clinicians with a better understanding of nonadherence to ARV treatment and to review the various factors that have been associated with either adherence or nonadherence. Strategies are presented that may help the nonadherent individual become ready to take HIV medications as prescribed.

  5. Factors contributing to the longitudinal development of social participation in individuals with cerebral palsy.

    Science.gov (United States)

    Tan, Siok Swan; van der Slot, Wilma M A; Ketelaar, Marjolijn; Becher, Jules G; Dallmeijer, Annet J; Smits, Dirk-Wouter; Roebroeck, Marij E

    2016-10-01

    We aimed to determine factors associated with the longitudinal development of social participation in a Dutch population of individuals with Cerebral Palsy (CP) aged 1-24 years. For this multicentre prospective longitudinal study, 424 individuals with CP aged 1-24 years were recruited from various rehabilitation centers in The Netherlands. Social participation was measured with the Vineland Adaptive Behavior Scales. We assessed associations with age, intellectual impairment, level of gross motor function, gender, type of CP, manual ability, epilepsy, hearing-, visual-, speech impairment and pain, internalizing- and externalizing behavioral problems, type of education and parental level of education. Each individual was measured 3 or 4 times. The time between measurements was 1 or 2 years. Epilepsy and speech impairment were each independently associated with the longitudinal development of social participation. The effects were rather small and did not change with age. Also, a trend was found that children attending special education develop less favorably in social participation. Our results might provide parents and caregivers with starting points to further develop tailored support for individuals with epilepsy, with speech impairment and/or attending special education at risk for suboptimal social participation. Copyright © 2016. Published by Elsevier Ltd.

  6. Theoretical Analysis of Occupational Development Aspects from the Viewpoint of the Personality's Constant Individual Traits Concept

    Science.gov (United States)

    Wilsz, Jolanta

    2015-01-01

    The concept of personality's constant individual traits and its significance, as well as implications for problems connected with choosing an occupation have been presented in the paper. Selected theories of occupational development have been analyzed from the concept viewpoint and certain traits of occupational personality presented by authors of…

  7. Ethics Education: Using Inductive Reasoning to Develop Individual, Group, Organizational, and Global Perspectives

    Science.gov (United States)

    Taft, Susan H.; White, Judith

    2007-01-01

    Ethics education that prepares students to address ethical challenges at work is a multifaceted and long-term endeavor. In this article, the authors propose an inductive ethics pedagogy that begins the process of ethics education by grounding students in their own individual ethical principles. The approach centers on developing students' ethical…

  8. An Assessment of Publication Productivity in Career Development and Transition for Exceptional Individuals: 1978-2012

    Science.gov (United States)

    Unger, Darlene D.; Rumrill, Phillip D., Jr.

    2013-01-01

    This literature review examined publication patterns in the journal of "Career Development and Transition for Exceptional Individuals" across 35 years of publication. Overall, 732 contributors affiliated with 267 organizations were identified in our analysis of 436 articles. Frequency counts identified the most productive scholars in…

  9. Developing teacher sensitivity to individual learning differences (ILDs) : Studies on increasing teacher effectiveness

    NARCIS (Netherlands)

    Rosenfeld, M.N.

    2008-01-01

    Effective teachers are sensitive to individual learning differences (ILDs). This dissertation investigates teacher changes as a result of eight long-term professional development (PD) courses (56-hours and 28-hours) designed to help them become more sensitive to ILDs. In these courses, the

  10. Missing Link: Integrated Individual Leadership Development, Employee Engagement, and Customer Value-Added Improvement

    Science.gov (United States)

    Heldenbrand, Lois; Simms, Michael S.

    2012-01-01

    Long-term care is a key public issue that affects all of us in some way at some time of our lives. Nowhere is performance improvement and quality management more imperative. Through an 8-month field study and follow-up case study, we discuss how using an integrated approach to individual leadership development, employee engagement, and customer…

  11. Development, Field Test, and Refinement of Performance Training Programs in Armor Advanced Individual Training. Final Report.

    Science.gov (United States)

    Young, Douglas L.; Taylor, John E.

    Performance-oriented instruction was developed, field tested, and refined in two Advanced Individual Training (AIT) programs--Armor Reconnaissance Specialist (MOS 11D) and Armor Crewman (MOS 11E). Tasks for both MOS (Military Occupational Specialty) were inventoried and the inventories were reduced by eliminating those tasks which are not required…

  12. Effect of sericin on preimplantation development of bovine embryos cultured individually.

    Science.gov (United States)

    Isobe, T; Ikebata, Y; Onitsuka, T; Wittayarat, M; Sato, Y; Taniguchi, M; Otoi, T

    2012-09-01

    The silk protein sericin has been identified as a potent antioxidant in mammalian cells. This study was conducted to examine the effects of sericin on preimplantation development and quality of bovine embryos cultured individually. When two-cell-stage embryos were cultured individually for 7 days in CR1aa medium supplemented with 0, 0.1, 0.5, or 1% sericin, rates of total blastocyst formation and development to expanded blastocysts from embryos cultured with 0.5% sericin were higher (P sericin. When embryos were cultured individually for 7 days in the CR1aa medium supplemented with 0 or 0.5% sericin under two oxidative stress conditions (50 or 100 μm H(2)O(2)), the addition of sericin significantly improved the blastocyst formation rate of embryos exposed to 100 μm H(2)O(2). However, the protective effect of sericin was not observed in development of embryos exposed to 50 μm H(2)O(2). When embryos were exposed to 100 μm H(2)O(2) during culture, the DNA fragmentation index of total blastocysts from embryos cultured with 0.5% sericin was lower than blastocysts derived from embryos cultured without sericin (4.4 vs. 6.8%; P sericin to in vitro culture medium improved preimplantation development and quality of bovine embryos cultured individually by preventing oxidative stress. Copyright © 2012 Elsevier Inc. All rights reserved.

  13. Individual differences in social comparison : Development of a scale of social comparison orientation

    NARCIS (Netherlands)

    Gibbons, FX; Buunk, BP

    Development and validation of a measure of individual differences in social comparison orientation (the Iowa-Netherlands Comparison Orientation Measure [INCOM]) are described. Assuming that the tendency toward social comparison is universal, the scale was constructed so as to be appropriate to and

  14. Saving for Success: Financial Education and Savings Goal Achievement in Individual Development Accounts

    Science.gov (United States)

    Grinstead, Mary L.; Mauldin, Teresa; Sabia, Joseph J.; Koonce, Joan; Palmer, Lance

    2011-01-01

    Using microdata from the American Dream Demonstration, the current study examines factors associated with savings and savings goal achievement (indicated by a matched withdrawal) among participants of individual development account (IDA) programs. Multinomial logit results show that hours of participation in financial education programs, higher…

  15. Training Class Inclusion Responding in Typically Developing Children and Individuals with Autism

    Science.gov (United States)

    Ming, Siri; Mulhern, Teresa; Stewart, Ian; Moran, Laura; Bynum, Kellie

    2018-01-01

    In a "class inclusion" task, a child must respond to stimuli as being involved in two different though hierarchically related categories. This study used a Relational Frame Theory (RFT) paradigm to assess and train this ability in three typically developing preschoolers and three individuals with autism spectrum disorder, all of whom had…

  16. SPSP Phase III Recruiting, Selecting, and Developing Secure Power Systems Professionals. Individual and Team Performance Guidelines

    Energy Technology Data Exchange (ETDEWEB)

    O' Neil, Lori Ross [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Conway, T. J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Tobey, D. H. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Greitzer, Frank L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Dalton, Angela C. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Pusey, Portia K. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-03-01

    The Secure Power Systems Professional Phase III final report was released last year which an appendix of Individual and Team Performance Guidelines. This new report is that appendix broken out as a standalone document to assist utilities in recruiting and developing Secure Power Systems Professionals at their site.

  17. The Development of Stranger Fear in Infancy and Toddlerhood: Normative Development, Individual Differences, Antecedents, and Outcomes

    Science.gov (United States)

    Brooker, Rebecca J.; Buss, Kristin A.; Lemery-Chalfant, Kathryn; Aksan, Nazan; Davidson, Richard J.; Goldsmith, H. Hill

    2013-01-01

    Despite implications that stranger fear is an important aspect of developing behavioral inhibition, a known risk factor for anxiety, normative and atypical developmental trajectories of stranger fear across infancy and toddlerhood remain understudied. We used a large, longitudinal data set (N = 1285) including multi-trait, multi-method assessments…

  18. Benefits of training and development for individuals and teams, organizations, and society.

    Science.gov (United States)

    Aguinis, Herman; Kraiger, Kurt

    2009-01-01

    This article provides a review of the training and development literature since the year 2000. We review the literature focusing on the benefits of training and development for individuals and teams, organizations, and society. We adopt a multidisciplinary, multilevel, and global perspective to demonstrate that training and development activities in work organizations can produce important benefits for each of these stakeholders. We also review the literature on needs assessment and pretraining states, training design and delivery, training evaluation, and transfer of training to identify the conditions under which the benefits of training and development are maximized. Finally, we identify research gaps and offer directions for future research.

  19. Challenges and Changes: Developing Teachers' and Initial Teacher Education Students' Understandings of the Nature of Science

    Science.gov (United States)

    Ward, Gillian; Haigh, Mavis

    2017-12-01

    Teachers need an understanding of the nature of science (NOS) to enable them to incorporate NOS into their teaching of science. The current study examines the usefulness of a strategy for challenging or changing teachers' understandings of NOS. The teachers who participated in this study were 10 initial teacher education chemistry students and six experienced teachers from secondary and primary schools who were introduced to an explicit and reflective activity, a dramatic reading about a historical scientific development. Concept maps were used before and after the activity to assess teachers' knowledge of NOS. The participants also took part in a focus group interview to establish whether they perceived the activity as useful in developing their own understanding of NOS. Initial analysis led us to ask another group, comprising seven initial teacher education chemistry students, to take part in a modified study. These participants not only completed the same tasks as the previous participants but also completed a written reflection commenting on whether the activity and focus group discussion enhanced their understanding of NOS. Both Lederman et al.'s (Journal of Research in Science Teaching, 39(6), 497-521, 2002) concepts of NOS and notions of "naive" and "informed" understandings of NOS and Hay's (Studies in Higher Education, 32(1), 39-57, 2007) notions of "surface" and "deep" learning were used as frameworks to examine the participants' specific understandings of NOS and the depth of their learning. The ways in which participants' understandings of NOS were broadened or changed by taking part in the dramatic reading are presented. The impact of the data-gathering tools on the participants' professional learning is also discussed.

  20. [Development of premature children: caregivers' understanding according to the Bioecological Theory].

    Science.gov (United States)

    Lemos, Rayla Amaral; Veríssimo, Maria de La Ó Ramallo

    2015-12-01

    Understanding the conceptions of premature children caregivers on child development and associated factors. An exploratory-descriptive qualitative study of 12 families with children under three years of age. Interviews were submitted to thematic content analysis, systematized into the categories of Bioecological Theory of Human Development: Process, Person, Context and Time, and in the Functional Development category. There are concerns about impairment in the current and future development of a Person/child defined as fragile as a result of premature birth (Time dimension), minimized by the scope of observable competencies such as motor skills. The Context, especially family and health services, and Proximal Processes, described as one-way caregiver interactions, are considered determinants of development. Functional Development is considered a natural consequence and result of education. The support network is crucial, supporting or limiting care. Concerns about the development mobilize caregivers to stimulate the premature child/person and requests family and healthcare assistance.

  1. It's Rather like Learning a Language: Development of talk and conceptual understanding in mechanics lessons

    Science.gov (United States)

    Rincke, Karsten

    2011-01-01

    Although a broad literature exists concerning the development of conceptual understanding of force and other topics within mechanics, little is known about the role and development of students' talk about the subject. The paper presents an in-depth investigation of students' talk whilst being introduced to the concept of force. The main research goal was to investigate and understand how students develop an understanding of the concept of force and how they use and understand the term 'force'. Therefore, we make relation to the research field of students' preconceptions and the field of second language learning. Two classes of students (N = 47) were videotaped during a time period of nine lessons, each transcribed and analysed using a category system. Additional data were obtained via written tasks, logs kept by the students, and tests. The detailed analysis of the talk and the results of the tests indicate that students face difficulties in using the term 'force' scientifically similar to those in a foreign language instruction. Vygotsky already recognised a relationship between learning in science and learning a language. In this paper, important aspects of this relationship are discussed based upon empirical data. We conclude that in some respects it might be useful to make reference to the research related to language learning when thinking about improving science education. In particular, according to Selinker's concept of interlanguage describing language-learning processes within language instruction, the language used by the students during physics lessons can be viewed as a 'scientific interlanguage'.

  2. Individual risk of cutaneous melanoma in New Zealand: developing a clinical prediction aid.

    Science.gov (United States)

    Sneyd, Mary Jane; Cameron, Claire; Cox, Brian

    2014-05-22

    New Zealand and Australia have the highest melanoma incidence rates worldwide. In New Zealand, both the incidence and thickness have been increasing. Clinical decisions require accurate risk prediction but a simple list of genetic, phenotypic and behavioural risk factors is inadequate to estimate individual risk as the risk factors for melanoma have complex interactions. In order to offer tailored clinical management strategies, we developed a New Zealand prediction model to estimate individual 5-year absolute risk of melanoma. A population-based case-control study (368 cases and 270 controls) of melanoma risk factors provided estimates of relative risks for fair-skinned New Zealanders aged 20-79 years. Model selection techniques and multivariate logistic regression were used to determine the important predictors. The relative risks for predictors were combined with baseline melanoma incidence rates and non-melanoma mortality rates to calculate individual probabilities of developing melanoma within 5 years. For women, the best model included skin colour, number of moles > =5 mm on the right arm, having a 1st degree relative with large moles, and a personal history of non-melanoma skin cancer (NMSC). The model correctly classified 68% of participants; the C-statistic was 0.74. For men, the best model included age, place of occupation up to age 18 years, number of moles > =5 mm on the right arm, birthplace, and a history of NMSC. The model correctly classified 67% of cases; the C-statistic was 0.71. We have developed the first New Zealand risk prediction model that calculates individual absolute 5-year risk of melanoma. This model will aid physicians to identify individuals at high risk, allowing them to individually target surveillance and other management strategies, and thereby reduce the high melanoma burden in New Zealand.

  3. A review and framework for understanding the potential impact of poor solid waste management on health in developing countries.

    Science.gov (United States)

    Ziraba, Abdhalah K; Haregu, Tilahun Nigatu; Mberu, Blessing

    2016-01-01

    The increase in solid waste generated per capita in Africa has not been accompanied by a commensurate growth in the capacity and funding to manage it. It is reported that less than 30% of urban waste in developing countries is collected and disposed appropriately. The implications of poorly managed waste on health are numerous and depend on the nature of the waste, individuals exposed, duration of exposure and availability of interventions for those exposed. To present a framework for understanding the linkages between poor solid waste management, exposure and associated adverse health outcomes. The framework will aid understanding of the relationships, interlinkages and identification of the potential points for intervention. Development of the framework was informed by a review of literature on solid waste management policies, practices and its impact on health in developing countries. A configurative synthesis of literature was applied to develop the framework. Several iterations of the framework were reviewed by experts in the field. Each linkage and outcomes are described in detail as outputs of this study. The resulting framework identifies groups of people at a heightened risk of exposure and the potential health consequences. Using the iceberg metaphor, the framework illustrates the pathways and potential burden of ill-health related to solid waste that is hidden but rapidly unfolding with our inaction. The existing evidence on the linkage between poor solid waste management and adverse health outcomes calls to action by all stakeholders in understanding, prioritizing, and addressing the issue of solid waste in our midst to ensure that our environment and health are preserved. A resulting framework developed in this study presents a clearer picture of the linkages between poor solid waste management and could guide research, policy and action.

  4. Developing Internet interventions to target the individual impact of stigma in health conditions

    Directory of Open Access Journals (Sweden)

    Neil Thomas

    2015-09-01

    Full Text Available A number of health problems are associated with significant stigma, a social phenomenon in which individuals become the object of negative stereotypes. In addition to experiencing negative reactions from others, stigmatised individuals and groups can experience harmful consequences when they internalise these negative prevailing attitudes. The objective of this paper was to consider the potential to develop Internet-based health-related interventions explicitly targeting the effects of stigma on the individual. A review of the literature was conducted to synthesise current conceptualisations of stigma and self-stigma across a number of groups, and to identify current intervention developments. Self-stigma reduction strategies developed for in-person services include cognitive reframing, myth busting, contact with other members of the stigmatised group, and disclosure promotion. The development and provision of interventions targeting self-stigma within an online environment is in its infancy. Our review considers there to be particular potential of online interventions for this target, associated with the capacity of the Internet to promote having contact with peers within one’s stigmatised group, and for user interaction and empowerment. We conclude that self-stigma is a domain in which there is significant potential for innovation with health-related interventions, and provide a number of recommendations for online intervention development.

  5. The everyday lives of video game developers: Experimentally understanding underlying systems/structures

    Directory of Open Access Journals (Sweden)

    Casey O'Donnell

    2009-03-01

    Full Text Available This essay examines how tensions between work and play for video game developers shape the worlds they create. The worlds of game developers, whose daily activity is linked to larger systems of experimentation and technoscientific practice, provide insights that transcend video game development work. The essay draws on ethnographic material from over 3 years of fieldwork with video game developers in the United States and India. It develops the notion of creative collaborative practice based on work in the fields of science and technology studies, game studies, and media studies. The importance of, the desire for, or the drive to understand underlying systems and structures has become fundamental to creative collaborative practice. I argue that the daily activity of game development embodies skills fundamental to creative collaborative practice and that these capabilities represent fundamental aspects of critical thought. Simultaneously, numerous interests have begun to intervene in ways that endanger these foundations of creative collaborative practice.

  6. Developing mathematics edutainment media for Android based on students’ understanding and interest: a teachers’ review

    Science.gov (United States)

    Setyaningrum, W.; Waryanto, N. H.

    2018-03-01

    This paper aimed to describe the development of interactive edutainment mathematics media using Construct 2 software for grade 7 Junior High School, and to determine the quality of the interactive edutainment media developed in regards to improve students’ understanding and interest. This research employs Research and Development design, which media was developed using ADDIE model consisting of analysing, designing, developing, implementing and evaluating. This paper focuses on the steps of development and validity of the interactive media from teachers’ point of view. The teachers review focuses on three aspects – instructional, audio-visual and operational design. The review suggested that the media was very good in regard to the three aspects, with the average score was 144.55 from the maximum score of 175. Several contexts used in the game, however, need to be adjusted to students age.

  7. SU-E-J-211: Development of Respiratory Training System Using Individual Characteristic Guiding Waveform.

    Science.gov (United States)

    Kang, S; Yoon, J; Kim, T; Suh, T

    2012-06-01

    The purpose of this study is to develop the respiratory training system using individual characteristic guiding waveform to reduce the impact of respiratory motion that causes artifact in radiation therapy. Respiratory training system was developed by LabView (National Instruments, version 8.6). The real-time respiratory signals were acquired using in-house developed belt type sensor and more user-comfortable HMD was used for visual guiding (Vuzix, Wrap 920). The respiratory training program consists of three main components. It is (1) respiratory signal reading and peak detection program (2) individual characteristic guiding waveform generation program (3) respiratory signals acquisition and visual guiding program. In order to evaluate the feasibility of in-house developed respiratory training system, 5 volunteers were included and their respiratory signals were acquired using the in-house developed belt-type sensor. Respiratory training system needs 10 free breathing cycles of each volunteer to make individual characteristic guiding waveform based on Fourier series and it guides patient's next breathing. For each volunteer, free breathing and guided breathing which uses individual characteristic guiding waveform were performed to acquire the respiratory cycles for 3 min. The root mean square error (RMSE) was computed to analyze improvement of respiratory regularity in period and displacement. It was found that respiratory regularity was improved by using respiratory training system. RMSE of guided breathing decreased up to 40% in displacement and 76% in period compared with free breathing. The average of RMSE was decreases from 0.012V to 0.008V in displacement and from 0.432 sec to 0.192 sec in period. In conclusion, since the guiding waveform was easy to follow for the volunteers, The respiratory regularity was significantly improved by using in-house developed respiratory training system. So it would be helpful to improve accuracy and efficiency during 4D-RT, 4

  8. Generating or developing grounded theory: methods to understand health and illness.

    Science.gov (United States)

    Woods, Phillip; Gapp, Rod; King, Michelle A

    2016-06-01

    Grounded theory is a qualitative research methodology that aims to explain social phenomena, e.g. why particular motivations or patterns of behaviour occur, at a conceptual level. Developed in the 1960s by Glaser and Strauss, the methodology has been reinterpreted by Strauss and Corbin in more recent times, resulting in different schools of thought. Differences arise from different philosophical perspectives concerning knowledge (epistemology) and the nature of reality (ontology), demanding that researchers make clear theoretical choices at the commencement of their research when choosing this methodology. Compared to other qualitative methods it has ability to achieve understanding of, rather than simply describing, a social phenomenon. Achieving understanding however, requires theoretical sampling to choose interviewees that can contribute most to the research and understanding of the phenomenon, and constant comparison of interviews to evaluate the same event or process in different settings or situations. Sampling continues until conceptual saturation is reached, i.e. when no new concepts emerge from the data. Data analysis focusses on categorising data (finding the main elements of what is occurring and why), and describing those categories in terms of properties (conceptual characteristics that define the category and give meaning) and dimensions (the variations within properties which produce specificity and range). Ultimately a core category which theoretically explains how all other categories are linked together is developed from the data. While achieving theoretical abstraction in the core category, it should be logical and capture all of the variation within the data. Theory development requires understanding of the methodology not just working through a set of procedures. This article provides a basic overview, set in the literature surrounding grounded theory, for those wanting to increase their understanding and quality of research output.

  9. Development of the living thing transportation systems worksheet on learning cycle model to increase student understanding

    Science.gov (United States)

    Rachmawati, E.; Nurohman, S.; Widowati, A.

    2018-01-01

    This study aims to know: 1) the feasibility LKPD review of aspects of the didactic requirements, construction requirements, technical requirements and compliance with the Learning Cycle. 2) Increase understanding of learners with Learning Model Learning Cycle in SMP N 1 Wates in the form LKPD. 3) The response of learners and educators SMP N 1 Wates to quality LKPD Transportation Systems Beings. This study is an R & D with the 4D model (Define, Design, Develop and Disseminate). Data were analyzed using qualitative analysis and quantitative analysis. Qualitative analysis in the form of advice description and assessment scores from all validates that was converted to a scale of 4. While the analysis of quantitative data by calculating the percentage of materializing learning and achievement using the standard gain an increased understanding and calculation of the KKM completeness evaluation value as an indicator of the achievement of students understanding. the results of this study yield LKPD IPA model learning Cycle theme Transportation Systems Beings obtain 108.5 total scores of a maximum score of 128 including the excellent category (A). LKPD IPA developed able to demonstrate an improved understanding of learners and the response of learners was very good to this quality LKPD IPA.

  10. Clinically significant personality traits in individuals at high risk of developing psychosis.

    Science.gov (United States)

    Sevilla-Llewellyn-Jones, Julia; Camino, Gustavo; Russo, Debra A; Painter, Michelle; Montejo, Angel L; Ochoa, Susana; Jones, Peter B; Perez, Jesus

    2018-03-01

    It is still unclear to what extent personality may influence the development of psychosis. We aimed to explore significant personality traits in individuals at high-risk (HR) for psychosis. Personalities of forty HR individuals and a matched sample of 40 healthy volunteers (HVs) were evaluated with the Millon Multiaxial Inventory (MCMI-III). They were also assessed with the Positive and Negative Symptoms Scale (PANSS), Beck Depression and Anxiety Inventories (BDI-II and BAI), Global Assessment of Functioning (GAF) and Mini-International Neuropsychiatric Interview (MINI 6.0.0). Fisher's exact test was employed to compare frequency of traits. Mann-Whitney U test and logistic regression were used to establish relationships between traits and symptoms, and the effect of age, sex and symptoms on such traits. Most HR individuals (97.5%) had at least one significant trait; 75% had personality disorders, mainly depressive, borderline or schizotypal. Only histrionic and narcissistic traits were more prevalent in HVs. Negative symptoms were related to schizoid and paranoid traits. Depression was more severe with borderline traits. Most HR individuals (67.6%) had more than one DSM-IV Axis I diagnosis, mainly depressive/anxiety disorders. Transition rate was low (5%). Certain personality profiles may not be markers for conversions to psychosis but contribute to high morbidity in HR individuals. Copyright © 2018 Elsevier B.V. All rights reserved.

  11. Exogenous growth factors do not affect the development of individually cultured murine embryos.

    Science.gov (United States)

    Herrick, Jason R; Greene-Ermisch, Alison F; Schoolcraft, William B; Krisher, Rebecca L

    2017-12-21

    The objective of this study was to evaluate the effects of multiple growth factors on the development of individually cultured murine embryos. Embryos produced by in vitro fertilization using in vitro (IVM) or in vivo (IVO) matured oocytes from three strains of mice (CF1, Swiss Webster, B6D2F1) were cultured individually (10 μl) in the absence (control) or presence of growth factors (paf, epidermal growth factor [EGF], insulin-like growth factor 1 [IGF-1], and granulocyte-macrophage colony-stimulating factor [GM-CSF]). Blastocyst formation, hatching, and blastocyst cell numbers (trophectoderm, inner cell mass, and total) were evaluated on days 4 and 5 of culture. Post-hatching development of CF1 IVO embryos was also evaluated in vitro and in vivo. The presence of growth factors did not improve the proportion of embryos forming blastocysts or initiating hatching for any of the types of embryos tested. The only significant (P embryos that formed blastocysts by day 5 in CF1 IVM embryos. The presence of growth factors also did not affect blastocyst cell numbers. For CF1 IVO embryos, the presence of growth factors during culture did not affect the proportion of embryos that attached to fibronectin-coated dishes, the size of the resulting outgrowths, or in vivo development following transfer. Combinations of paf, EGF, GM-CSF, and IGF-1 did not improve development of murine embryos cultured individually in a sequential medium containing a defined protein source.

  12. Effect of culture medium volume and embryo density on early mouse embryonic development: tracking the development of the individual embryo.

    Science.gov (United States)

    Dai, Shan-Jun; Xu, Chang-Long; Wang, Jeffrey; Sun, Ying-Pu; Chian, Ri-Cheng

    2012-07-01

    To determine the optimal volume or density of embryos for the well-of-the-well (WOW) system in order to track the development of individual embryos and to determine whether the WOW system can reverse the negative impact of culturing embryos singly. (1) Mouse embryos (groups of nine at the 2-cell stage) were cultured in 6.25 μl, 12.50 μl, 25.00 μl and 50.00 μl of droplets of culture medium under paraffin oil; (2) Groups of three, six, nine and twelve embryos at the 2-cell stage were cultured in 50 μl of droplet of culture medium under paraffin oil; (3) Groups of nine embryos at the 2-cell stage were cultured in 50 μl of droplet under paraffin oil with or without nine micro-wells made on the bottom of the Petri dish into each of which were placed one of the nine embryos (WOW system). Also single 2-cell stage embryos was cultured individually in 5.5 μl of droplet of culture medium under paraffin oil with or without a single micro-well made on the bottom of the Petri dish (WOW system for single culture). At the end of culture, the percentages of blastocyst development, hatching and hatched blastocysts were compared in each group. The blastocysts were fixed for differential staining. The blastocyst development was significantly higher (P WOW system. The blastocyst development was not improved when single embryo cultured individually in a micro-well was compared to single embryo cultured individually without micro-well. The total cell numbers of blastocysts were significantly higher in group embryo culture than single embryo culture regardless of whether the WOW system was used. In addition, the total cell numbers of blastocysts were significantly higher (P WOW system than without. Group embryo culture is superior to single embryo culture for blastocyst development. The WOW system with 50 μl of droplet of culture medium can be used to track the individual development of embryo cultured in groups while preserving good embryonic development. The reduced

  13. Using Metasynthesis to Develop Sensitising Concepts to Understand Torres Strait Islander Migration

    OpenAIRE

    Mosby, Vinnitta Patricia

    2013-01-01

    Emerging research indicates that more and more Indigenous peoples will be forced to migrate due to climate change. Current responses focus on mitigation and adaptation strategies. One such group, Torres Strait Islander people are already moving for other reasons and existing vulnerabilities compound levels of disadvantage when moving. It will be important to understand Torres Strait Islander people’s experiences of contemporary movements in order to inform policy development and facilitate th...

  14. Marketers Understanding Engineers and Engineers Understanding Marketers: The Opportunities and Constraints of a Cross-Discipline Course Using 3D Printing to Develop Marketable Innovations

    Science.gov (United States)

    Reifschneider, Louis; Kaufman, Peter; Langrehr, Frederick W.; Kaufman, Kristina

    2015-01-01

    Marketers are criticized for not understanding the steps in the engineering research and development process and the challenges of manufacturing a new product at a profit. Engineers are criticized for not considering the marketability of and customer interest in such a product during the planning stages. With the development of 3D printing, rapid…

  15. Developing Public Health Initiatives through Understanding Motivations of the Audience at Mass-Gathering Events.

    Science.gov (United States)

    Hutton, Alison; Ranse, Jamie; Munn, Matthew Brendan

    2018-04-01

    This report identifies what is known about audience motivations at three different mass-gathering events: outdoor music festivals, religious events, and sporting events. In light of these motivations, the paper discusses how these can be harnessed by the event organizer and Emergency Medical Services. Lastly, motivations tell what kinds of interventions can be used to achieve an understanding of audience characteristics and the opportunity to develop tailor-made programs to maximize safety and make long-lasting public health interventions to a particular "cohort" or event population. A lot of these will depend on what the risks/hazards are with the particular populations in order to "target" them with public health interventions. Audience motivations tell the event organizer and Emergency Medical Services about the types of behaviors they should expect from the audience and how this may affect their health while at the event. Through these understandings, health promotion and event safety messages can be developed for a particular type of mass-gathering event based on the likely composition of the audience in attendance. Health promotion and providing public information should be at the core of any mass-gathering event to minimize public health risk and to provide opportunities for the promotion of healthy behaviors in the local population. Audience motivations are a key element to identify and agree on what public health information is needed for the event audience. A more developed understanding of audience behavior provides critical information for event planners, event risk managers, and Emergency Medical Services personnel to better predict and plan to minimize risk and reduce patient presentations at events. Mass-gathering event organizers and designers intend their events to be positive experiences and to have meaning for those who attend. Therefore, continual vigilance to improve public health effectiveness and efficiency can become best practice at events

  16. Pathways to Higher Education for Native Hawaiian Individual Development Account Participants

    OpenAIRE

    David W. Rothwell

    2013-01-01

    As the cost of higher education rises, a growing body of theory and research suggests that asset holding in the form of savings and net worth positively influence education expectations and outcomes. Native Hawaiians, like other Indigenous peoples, have disproportionately low college enrollment and graduation rates tied to a history of colonization. Using data from an Individual Development Account (IDA) program for Native Hawaiians, I examine the trajectories through the program and find: (a...

  17. DEVELOPMENT OF A MEASUREMENT SCALE FOR ABSORPTIVE CAPACITY AT THE INDIVIDUAL LEVEL

    DEFF Research Database (Denmark)

    Pedrosa, Alex; Jasmand, Claudia; Heidemann Lassen, Astrid

    2010-01-01

    The study of absorptive capacity (ACAP) has received quite some attention in the literature, as it emphasizes the capability to acquire and implement new knowledge which is important for knowledge creation and innovation in organizations. The concept has conceptually been argued to reside...... at the micro level of organizations. The present paper focuses on developing and empirically validating an appropriate measurement scale for individual-level ACAP....

  18. Development of a measurement scale for absorptive capacity at the individual-level

    DEFF Research Database (Denmark)

    Pedrosa, Alex; Jasmand, Claudia; Heidemann Lassen, Astrid

    2010-01-01

    The study of absorptive capacity (ACAP) has received quite some attention in the literature, as it emphasizes the capability to acquire and implement new knowledge which is important for knowledge creation and innovation in organizations. The concept has conceptually been argued to reside...... at the micro level of organizations. The present paper focuses on developing and empirically validating an appropriate measurement scale for individual-level ACAP....

  19. Fundamental understanding and development of low-cost, high-efficiency silicon solar cells

    Energy Technology Data Exchange (ETDEWEB)

    ROHATGI,A.; NARASIMHA,S.; MOSCHER,J.; EBONG,A.; KAMRA,S.; KRYGOWSKI,T.; DOSHI,P.; RISTOW,A.; YELUNDUR,V.; RUBY,DOUGLAS S.

    2000-05-01

    The overall objectives of this program are (1) to develop rapid and low-cost processes for manufacturing that can improve yield, throughput, and performance of silicon photovoltaic devices, (2) to design and fabricate high-efficiency solar cells on promising low-cost materials, and (3) to improve the fundamental understanding of advanced photovoltaic devices. Several rapid and potentially low-cost technologies are described in this report that were developed and applied toward the fabrication of high-efficiency silicon solar cells.

  20. Individualized teaching aimed at stimulating the development of talent and creativity in students

    Directory of Open Access Journals (Sweden)

    Arsić Zvezdan M.

    2013-01-01

    Full Text Available The time in which we live is characterized by rapid and conflicting changes as well as the development of all segments of social life. Access to the civilization of knowledge whose objectives, processes, and outcomes confirm that the human factor is becoming a leading cause of progress, requires redefinition of the relationship between society and schools. In the process of the cultural development, there is a need for talented and creative members of society who are going to be prepared for the leading roles through the educational system. However, in the teaching process, the gifted and creative students very often face a number of difficulties and problems that interfere with their optimal development. They are primarily victims of ignorance and disregard of individual differences among children of the same age, even children with the same IQ. For this reason, the main focus of this paper is on creating the conditions that can contribute to overcoming the problems that gifted and creative students encounter in the present circumstances of the organization and application of the process. Individualized instruction is a reasonable basis for success in this area, since it allows the contents, organization, methods and means of teaching, and learning adapt to individual differences, needs and abilities of students.

  1. Understanding women's experiences of developing an eating disorder and recovering: a life-history approach.

    Science.gov (United States)

    Patching, Joanna; Lawler, Jocalyn

    2009-03-01

    Qualitative inquiry into eating disorders is burgeoning, offering valuable and innovative insights into various aspects of the condition. This study used life-history interviews with 20 women who had recovered from anorexia nervosa, bulimia nervosa or both and who had remained healthy. The interviews focused on the women's narratives and experience rather than a diagnostic therapeutic model. Three themes of control, connectedness and conflict emerged as significant in the development, experience of, and recovery from an eating disorder. The development of the condition was attributed to a lack of control, a sense of non-connectedness to family and peers and extreme conflict with significant others. Recovery occurred when the women re-engaged with life, developed skills necessary for conflict resolution and rediscovered their sense of self. Rather than viewing the development of, and recovery from an eating disorder as separate and discrete events, the data from the life-history interviews suggest they are better viewed as one entity - that is, the journey of an individual attempting to discover and develop their sense of self. This perspective challenges some current constructs of eating disorders; it is not a condition in and of itself but a symptom of deeper issues that if addressed, when the individual is 'ready' to make that choice, will lead to recovery.

  2. Development and validation of a method for measuring depth of understanding in constructivist learning

    Science.gov (United States)

    Guarino, Lucia Falsetti

    A method for measuring depth of understanding of students in the middle-level science classroom was developed and validated. A common theme in the literature on constructivism in science education is that constructivist pedagogy, as opposed to objectivist pedagogy, results in a greater depth of understanding. Since few instruments measuring this construct exist at the present time, the development of such a tool to measure this construct was a significant contribution to the current body of assessment technologies in science education. The author's Depth of Understanding Assessment (DUA) evolved from a writing measure originally designed as a history assessment. The study involved 230 eighth grade science students studying a chemical change unit. The main research questions were: (1) What is the relationship between the DUA and each of the following independent variables: recall, application, and questioning modalities as measured by the Cognitive Preference Test; deep, surface, achieving, and deep-achieving approaches as measured by the Learning Process Questionnaire; achievement as measured by the Chemical Change Quiz, and teacher perception of student ability to conceptualize science content? (2) Is there a difference in depth of understanding, as measured by the DUA, between students who are taught by objectivist pedagogy and students who are taught by constructivist pedagogy favoring the constructivist group? (3) Is there a gender difference in depth of understanding as measured by the DUA? (4) Do students who are taught by constructivist pedagogy perceive their learning environment as more constructivist than students who are taught by objectivist pedagogy? Six out of nine hypothesis tests supported the validity of the DUA. The results of the qualitative component of this study which consisted of student interviews substantiated the quantitative results by providing additional information and insights. There was a significant difference in depth of

  3. Promoting Teacher Professional Development: the Role of Individual and Contextual Factors

    Directory of Open Access Journals (Sweden)

    Zahra Rastegar Haghighi Shirazi

    2015-01-01

    Full Text Available The purpose of this study was to investigate the individual and contextual factors conducive to teacher professional development. The study which aimed at identifying the predictors of teacher development consisted of in-depth interviews with 15 teachers. Data gleaned from in-depth interviews were analyzed utilizing content analysis. Some common themes that emerged from the qualitative data included (a learning goal orientation (b teacher self-efficacy, (c professional commitment (d organizational climate, and (e learning organization culture.  Theoretical and practical implications of the study are discussed.

  4. Why should I care? Engaging students in conceptual understanding using global context to develop social attitudes.

    Science.gov (United States)

    Forder, S. E.; Welstead, C.; Pritchard, M.

    2014-12-01

    A glance through the Harvard Business Review reveals many suggestions and research pieces reviewing sales and marketing techniques. Most educators will be familiar with the notion that making accurate first impressions and being responsive, whilst maintaining pace is critical to engaging an audience. There are lessons to be learnt from industry that can significantly impact upon our teaching. Eisenkraft, in his address to the NSTA, proposed four essential questions. This presentation explores one of those questions: 'Why should I care?', and discusses why this question is crucial for engaging students by giving a clear purpose for developing their scientific understanding. Additionally, this presentation explores how The ISF Academy has adapted the NGSS, using the 14 Grand Engineering Challenges and the IB MYP, to provide current, authentic global contexts, in order to give credibility to the concepts, understandings and skills being learnt. The provision of global contexts across units and within lessons supports a platform for students to have the freedom to explore their own sense of social responsibility. The Science Department believes that planning lessons with tasks that elaborate on the student's new conceptualisations, has helped to transfer the student's new understanding into social behavior beyond the classroom. Furthermore, extension tasks have been used to transfer conceptual understanding between different global contexts.

  5. Understanding political development through an intersectionality framework: Life stories of disability activists

    Directory of Open Access Journals (Sweden)

    Akemi Nishida

    2016-05-01

    Full Text Available This article explores how those who do not share their marginalized identities with their surrounding people (e.g., family members and thus community resources relating to these identities, initiate and experience political development. The concept of intersectionality is used as an analytical tool to examine how one's political development is mediated via one's intersecting identities, communities, and experience of social in/justices. Life story interviews were conducted with disabled activists to explore this question. The stories reveal how these activists, who had initially resisted identifying as disabled for various reasons, eventually used the politicizing experiences from nondisability identities and communities to reframe and reclaim their disability status. By tracing the political developments of disabled people, this article places importance on understanding the process in a holistic way and on developing activist communities and movements that acknowledge intersecting identities and in/justices.

  6. Development of a nomogram for individualizing hip fracture risk in men and women.

    Science.gov (United States)

    Nguyen, N D; Frost, S A; Center, J R; Eisman, J A; Nguyen, T V

    2007-08-01

    Until now there has been no published prognostic tool available for predicting of hip fracture to primary care settings. We have developed a nomogram for predicting the absolute risk of hip fracture for any individual by using clinical factors, including age, prior fracture and fall, in addition to BMD that was based on a 15-year follow-up cohort study. Bone mineral density or clinical risk factors alone are useful but limited tools for the identification of individuals with high-risk of hip fracture. It is hypothesized that the combination of clinical risk factors and BMD can improve the accuracy of fracture prediction. This study was aimed at developing a nomogram which combines these factors for predicting 5-year and 10-year risk of hip fracture for an individual. The study, designed as a epidemiologic, community-based prospective study, included 1,208 women and 740 men aged 60+ years with median duration of follow-up of 13 years (inter-quartile range, IQR: 6-14) for both women and men, yielding 10,523 and 7,586 person-years of observation, respectively. Main outcome measures were incidence of hip fractures and risk factors were femoral neck bone mineral density (FNBMD), prior fracture, history of fall, postural sway and quadriceps strength. Femoral neck BMD was measured by DXA (GE-LUNAR Corp, Madison, Wisconsin, USA). Cox's proportional hazards model was used to estimate the risk of fracture for individuals, and a nomogram was constructed for predicting hip fracture risk. Between 1989 and 2004, 127 individuals (96 women) sustained a hip fracture. Advancing age, low femoral neck BMD, prior fracture and history of falls were independent predictors of hip fracture. The area under the receiver operating characteristic curve for the model was 0.85 for both sexes. A nomogram was constructed for predicting hip fracture risk for an individual. Among those aged 75 or older with BMD T-scores men was comparable to or higher than in women; however, in younger age groups

  7. Visual perceptual load reduces auditory detection in typically developing individuals but not in individuals with autism spectrum disorders.

    Science.gov (United States)

    Tillmann, Julian; Swettenham, John

    2017-02-01

    Previous studies examining selective attention in individuals with autism spectrum disorder (ASD) have yielded conflicting results, some suggesting superior focused attention (e.g., on visual search tasks), others demonstrating greater distractibility. This pattern could be accounted for by the proposal (derived by applying the Load theory of attention, e.g., Lavie, 2005) that ASD is characterized by an increased perceptual capacity (Remington, Swettenham, Campbell, & Coleman, 2009). Recent studies in the visual domain support this proposal. Here we hypothesize that ASD involves an enhanced perceptual capacity that also operates across sensory modalities, and test this prediction, for the first time using a signal detection paradigm. Seventeen neurotypical (NT) and 15 ASD adolescents performed a visual search task under varying levels of visual perceptual load while simultaneously detecting presence/absence of an auditory tone embedded in noise. Detection sensitivity (d') for the auditory stimulus was similarly high for both groups in the low visual perceptual load condition (e.g., 2 items: p = .391, d = 0.31, 95% confidence interval [CI] [-0.39, 1.00]). However, at a higher level of visual load, auditory d' reduced for the NT group but not the ASD group, leading to a group difference (p = .002, d = 1.2, 95% CI [0.44, 1.96]). As predicted, when visual perceptual load was highest, both groups then showed a similarly low auditory d' (p = .9, d = 0.05, 95% CI [-0.65, 0.74]). These findings demonstrate that increased perceptual capacity in ASD operates across modalities. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  8. Transcriptomic analysis in the developing zebrafish embryo after compound exposure: Individual gene expression and pathway regulation

    Energy Technology Data Exchange (ETDEWEB)

    Hermsen, Sanne A.B., E-mail: Sanne.Hermsen@rivm.nl [Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), P.O. Box 1, 3720 BA Bilthoven (Netherlands); Department of Toxicogenomics, Maastricht University, P.O. Box 616, 6200 MD, Maastricht (Netherlands); Institute for Risk Assessment Sciences (IRAS), Utrecht University, P.O. Box 80.178, 3508 TD, Utrecht (Netherlands); Pronk, Tessa E. [Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), P.O. Box 1, 3720 BA Bilthoven (Netherlands); Department of Toxicogenomics, Maastricht University, P.O. Box 616, 6200 MD, Maastricht (Netherlands); Brandhof, Evert-Jan van den [Centre for Environmental Quality, National Institute for Public Health and the Environment (RIVM), P.O. Box 1, 3720 BA Bilthoven (Netherlands); Ven, Leo T.M. van der [Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), P.O. Box 1, 3720 BA Bilthoven (Netherlands); Piersma, Aldert H. [Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), P.O. Box 1, 3720 BA Bilthoven (Netherlands); Institute for Risk Assessment Sciences (IRAS), Utrecht University, P.O. Box 80.178, 3508 TD, Utrecht (Netherlands)

    2013-10-01

    The zebrafish embryotoxicity test is a promising alternative assay for developmental toxicity. Classically, morphological assessment of the embryos is applied to evaluate the effects of compound exposure. However, by applying differential gene expression analysis the sensitivity and predictability of the test may be increased. For defining gene expression signatures of developmental toxicity, we explored the possibility of using gene expression signatures of compound exposures based on commonly expressed individual genes as well as based on regulated gene pathways. Four developmental toxic compounds were tested in concentration-response design, caffeine, carbamazepine, retinoic acid and valproic acid, and two non-embryotoxic compounds, D-mannitol and saccharin, were included. With transcriptomic analyses we were able to identify commonly expressed genes, which were mostly development related, after exposure to the embryotoxicants. We also identified gene pathways regulated by the embryotoxicants, suggestive of their modes of action. Furthermore, whereas pathways may be regulated by all compounds, individual gene expression within these pathways can differ for each compound. Overall, the present study suggests that the use of individual gene expression signatures as well as pathway regulation may be useful starting points for defining gene biomarkers for predicting embryotoxicity. - Highlights: • The zebrafish embryotoxicity test in combination with transcriptomics was used. • We explored two approaches of defining gene biomarkers for developmental toxicity. • Four compounds in concentration-response design were tested. • We identified commonly expressed individual genes as well as regulated gene pathways. • Both approaches seem suitable starting points for defining gene biomarkers.

  9. Islam - Science Integration Approach in Developing Chemistry Individualized Education Program (IEP for Students with Disabilities

    Directory of Open Access Journals (Sweden)

    Jamil Suprihatiningrum

    2017-11-01

    Full Text Available The paper is based on a research which tries to explore, explain and describe Islam - science integration approach to develop an Individualized Education Program (IEP for students with disabilities in chemistry lesson. As a qualitative case study, this paper is aimed at investigating how Islam - science integration approach can be underpinned for developing the IEP for Chemistry. Participants were recruited purposively and data were collected by interviews; documents’ analysis; and experts’ assessment (i.e. material experts, inclusive education experts, media experts, chemistry teachers and support teachers, then analyzed using content-analysis. The result shows Islam - science integration approach can be a foundation to develop the chemistry IEP by seeking support for the verses of the Qur'an and corresponding hadiths. Even although almost all the subject matter in chemistry can be integrated with Islamic values, this study only developed two contents, namely Periodic System of Elements and Reaction Rate.

  10. Developing a shared understanding of the Upper Mississippi River: the foundation of an ecological resilience assessment

    Science.gov (United States)

    Bouska, Kristen; Houser, Jeff N.; De Jager, Nathan R.; Hendrickson, Jon S.

    2018-01-01

    The Upper Mississippi River System (UMRS) is a large and complex floodplain river ecosystem that spans the jurisdictions of multiple state and federal agencies. In support of ongoing ecosystem restoration and management by this broad partnership, we are undertaking a resilience assessment of the UMRS. We describe the UMRS in the context of an ecological resilience assessment. Our description articulates the temporal and spatial extent of our assessment of the UMRS, the relevant historical context, the valued services provided by the system, and the fundamental controlling variables that determine its structure and function. An important objective of developing the system description was to determine the simplest, adequate conceptual understanding of the UMRS. We conceptualize a simplified UMRS as three interconnected subsystems: lotic channels, lentic off-channel areas, and floodplains. By identifying controlling variables within each subsystem, we have developed a shared understanding of the basic structure and function of the UMRS, which will serve as the basis for ongoing quantitative evaluations of factors that likely contribute to the resilience of the UMRS. As we undertake the subsequent elements of a resilience assessment, we anticipate our improved understanding of interactions, feedbacks, and critical thresholds will assist natural resource managers to better recognize the system’s ability to adapt to existing and new stresses.

  11. Development of a Systems Science Curriculum to Engage Rural African American Teens in Understanding and Addressing Childhood Obesity Prevention.

    Science.gov (United States)

    Frerichs, Leah; Hassmiller Lich, Kristen; Young, Tiffany L; Dave, Gaurav; Stith, Doris; Corbie-Smith, Giselle

    2017-08-01

    Engaging youth from racial and ethnic minority communities as leaders for change is a potential strategy to mobilize support for addressing childhood obesity, but there are limited curricula designed to help youth understand the complex influences on obesity. Our aim was to develop and pilot test a systems science curriculum to elicit rural African American youth perspectives on childhood obesity and enhance their understanding of and support for obesity prevention solutions. The curriculum was designed so it could be integrated with existing positive youth development curricula that help youth advocate for and implement identified solutions. We conducted four workshop sessions with youth that engaged them in systems learning activities such as guided systems diagramming activities. The participants ( n = 21) completed validated surveys presession and postsession that assessed their causal attributions of obesity and support for obesity prevention policies. The youths' perception that environmental factors cause obesity increased ( p < .05), and perceptions that individual behavior and biology cause obesity did not change. Their support for policies that addressed food access and food pricing significantly increased ( p < .05). The youths' system diagrams elucidated links between multilevel factors such as personal attitudes, social influence, and the built environment, which provides important information for designing synergistic solutions. The changes we observed in youths' perceptions of obesity and support for policy changes have important implications for youths' interest and willingness to advocate for social and environmental changes in their community. The strategies have a promising role in supporting community mobilization to address childhood obesity.

  12. Guiding students to develop an understanding of scientific inquiry: a science skills approach to instruction and assessment.

    Science.gov (United States)

    Stone, Elisa M

    2014-01-01

    New approaches for teaching and assessing scientific inquiry and practices are essential for guiding students to make the informed decisions required of an increasingly complex and global society. The Science Skills approach described here guides students to develop an understanding of the experimental skills required to perform a scientific investigation. An individual teacher's investigation of the strategies and tools she designed to promote scientific inquiry in her classroom is outlined. This teacher-driven action research in the high school biology classroom presents a simple study design that allowed for reciprocal testing of two simultaneous treatments, one that aimed to guide students to use vocabulary to identify and describe different scientific practices they were using in their investigations-for example, hypothesizing, data analysis, or use of controls-and another that focused on scientific collaboration. A knowledge integration (KI) rubric was designed to measure how students integrated their ideas about the skills and practices necessary for scientific inquiry. KI scores revealed that student understanding of scientific inquiry increased significantly after receiving instruction and using assessment tools aimed at promoting development of specific inquiry skills. General strategies for doing classroom-based action research in a straightforward and practical way are discussed, as are implications for teaching and evaluating introductory life sciences courses at the undergraduate level.

  13. Gender identity, gender assignment and reassignment in individuals with disorders of sex development: a major of dilemma.

    Science.gov (United States)

    Fisher, A D; Ristori, J; Fanni, E; Castellini, G; Forti, G; Maggi, M

    2016-11-01

    Disorders of Sex Development (DSD) are a wide range of congenital conditions characterized by an incongruence of components involved in sexual differentiation, including gender psychosexual development. The management of such disorders is complex, and one of the most crucial decision is represented by gender assignment. In fact, the primary goal in DSD is to have a gender assignment consistent with the underlying gender identity in order to prevent the distress related to a forthcoming Gender Dysphoria. Historically, gender assignment was based essentially on surgical outcomes, assuming the neutrality of gender identity at birth. This policy has been challenged in the past decade refocusing on the importance of prenatal and postnatal hormonal and genetic influences on psychosexual development. (1) to update the main psychological and medical issues that surround DSD, in particular regarding gender identity and gender assignment; (2) to report specific clinical recommendations according to the different diagnosis. A systematic search of published evidence was performed using Medline (from 1972 to March 2016). Review of the relevant literature and recommendations was based on authors' expertise. A review of gender identity and assignment in DSD is provided as well as clinical recommendations for the management of individuals with DSD. Given the complexity of this management, DSD individuals and their families need to be supported by a specialized multidisciplinary team, which has been universally recognized as the best practice for intersexual conditions. In case of juvenile GD in DSD, the prescription of gonadotropin-releasing hormone analogues, following the World Professional Association for Transgender Health and the Endocrine Society guidelines, should be considered. It should always be taken into account that every DSD person is unique and has to be treated with individualized care. In this perspective, international registries are crucial to improve the

  14. Development of a Two-Dimensional Array of Individually Addressable Micro-Mirrors for NGST Application

    Science.gov (United States)

    Dutta, S. B.; Mott, D. B.; Allen, C. A.; Ewin, A. J.; Jhabvala, M. D.; Kotecki, C. A.; Kuhn, J. L.; MacKenty, J. W.

    2000-05-01

    NASA's missions of the 21st century will use small, low cost, efficient instruments for Earth and Space Science studies. Development of technologies that accommodate these requirements is essential for space applications. Micro Electro Mechanical Systems (MEMS) technology development for sensors and actuators plays a major role in this effort. We are developing a two dimensional array of individually addressable, cryogenic micro-mirrors, a MEMS based component, specifically for application in the Multi Object Spectrometer (MOS) in NGST. Two-dimensional, individually addressable and tiltable aluminum micro-mirror-arrays (MMA) have been developed and prototype arrays of different sizes have been fabricated in the Detector Development Laboratory of NASA, GSFC. Each micro-mirror of the array has 100micronx100micron pixel size and is capable of tilting +/- 10 degrees by electrostatic actuation. We have completed extensive analytical studies and performed laboratory tests to compare model predictions with actual performance of a 3x3 array. The mirrors have been tested to operate at cryogenic temperature. Recently we have completed the integration of a CMOS based address and driver circuit for the MMA with its mechanical structure. Our goal is to extend the development to a 1024x1024 array, primarily for NGST and also for other imaging and spectroscopy applications. For NGST MOS, MMAs will be used as a reflective slit-mask at a focal plane of the spectrometer providing a large field of view together with diffraction limited angular resolution for a grating spectrometer. Selected areas of the mirror-array will be tilted to select portions of the scene so that observation of up to 1000 simultaneous spectra of sparse targets will be possible. This provides a factor of 100 improvement in observing speed over conventional spectrometers. Details of the technology development along with its application to NGST will be discussed. This work is supported by the GSFC Director

  15. UNDERSTANDING THAI CULTURE AND ITS IMPACT ON REQUIREMENTS ENGINEERING PROCESS MANAGEMENT DURING INFORMATION SYSTEMS DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    Theerasak Thanasankit

    2002-01-01

    Full Text Available This paper explores the impact of Thai culture on managing the decision making process in requirements engineering and contribution a better understand of its influence on the management of requirements engineering process. The paper illustrates the interaction of technology and culture and shows that rather than technology changing culture, culture can change the way technology is used. Thai culture is naturally inherent in Thai daily life and Thais bring that into their work practices. The concepts of power and uncertainty in Thai culture contribute toward hierarchical forms of communication and decision making process in Thailand, especially during requirements engineering, where information systems requirements need to be established for further development. The research shows that the decision making process in Thailand tends to take a much longer time, as every stage during requirements engineering needs to be reported to management for final decisions. The tall structure of Thai organisations also contributes to a bureaucratic, elongated decision-making process during information systems development. Understanding the influence of Thai culture on requirements engineering and information systems development will assist multinational information systems consulting organisations to select, adapt, better manage, or change requirements engineering process and information systems developments methodologies to work best with Thai organisations.

  16. Understanding of Grassland Ecosystems under Climate Change and Economic Development Pressures in the Mongolia Plateau

    Science.gov (United States)

    Qi, J.; Chen, J.; Shan, P.; Pan, X.; Wei, Y.; Wang, M.; Xin, X.

    2011-12-01

    The land use and land cover change, especially in the form of grassland degradation, in the Mongolian Plateau, exhibited a unique spatio-temporal pattern that is a characteristic of a mixed stress from economic development and climate change of the region. The social dimension of the region played a key role in shaping the landscape and land use change, including the cultural clashes with economic development, conflicts between indigenous people and business ventures, and exogenous international influences. Various research projects have been conducted in the region to focus on physical degradation of grasslands and/or on economic development but there is a lack of understanding how the social and economic dimensions interact with grassland ecosystems and changes. In this talk, a synthesis report was made based on the most recent workshop held in Hohhot, Inner Mongolia, of China, that specifically focused on climate change and grassland ecosystems. The report analyzed the degree of grassland degradation, its climate and social drivers, and coupling nature of economic development and conservation of traditional grassland values. The goal is to fully understand the socio-ecological-economic interactions that together shape the trajectory of the grassland ecosystems in the Mongolia Plateau.

  17. Curriculum development through understanding the student nurse experience of suicide intervention education--A phenomenographic study.

    Science.gov (United States)

    Heyman, Inga; Webster, Brian J; Tee, Stephen

    2015-11-01

    Suicide remains a global public health issue and a major governmental concern. The World Health Organisation argues for continued investment in education for front-line professionals, with a particular focus on nurses, to address the rising suicide levels. Considering this rate, it could be argued that suicide has impacted on the lives of many, including the student nurse population. Understanding the psychological impact, and influence on learning, whilst developing suicide intervention knowledge is crucial. However, little is known of the student experience in this complex and challenging area of skills development. This phenomenographic study examines the experiences of second year Bachelor of Nursing (mental health) students who participated in the Applied Suicide Intervention Skills Training (ASIST). Experiences were illuminated through two focus groups, Experiences were distilled and categorised through hierarchically relationships to construct a group experiential field to illustrate understandings of the impact this approach has on learning Students found ASIST to be emotionally challenging yet an extremely positive experience through bonding, peer learning, and class cohesion. The supportive workshop facilitation was essential allowing for full immersion into role simulation thus developing student confidence. Appropriate pedagogy and student support must be considered whilst developing suicide intervention in the pre-registration curricula. Copyright © 2015 Elsevier Ltd. All rights reserved.

  18. Premaxillary-maxillary suture asymmetry in a juvenile Gorilla. Implications for understanding dentofacial growth and development.

    Science.gov (United States)

    Schwartz, J H

    1983-01-01

    A specimen of juvenile gorilla was found that had the premaxillary-maxillary suture coursing between the lateral deciduous incisor and deciduous canine on one side of the jaw, but between the central and lateral deciduous incisors on the other; in the latter, the suture also separates the alveolus of the lateral deciduous incisor from the crypt of the growing successional lateral incisor. Rather than dismiss this exception to the traditional dictum of tooth identification--which is based on the position to teeth relative to this suture--as some inconsequential anomaly, an attempt is made to understand how this can occur within the confines of present understanding of dentofacial growth and development and developmental theory. An hypothesis relating tooth and tooth class identification is presented in the context of ectomesenchymally predifferentiated stem progenitors and subsequent tooth class proliferation.

  19. LEARNING IN FRIENDSHIP GROUPS: DEVELOPING STUDENTS’ CONCEPTUAL UNDERSTANDING THROUGH SOCIAL INTERACTION

    Directory of Open Access Journals (Sweden)

    Carl eSenior

    2014-09-01

    Full Text Available The role that student friendship groups play in learning was investigated here. Employing a critical realist design, two focus groups on undergraduates were conducted to explore their experience of studying. Data from the ‘case-by-case’ analysis suggested student-to-student friendships produced social contexts which facilitated conceptual understanding through discussion, explanation and application to ‘real life’ contemporary issues. However, the students did not conceive this as a learning experience or suggest the function of their friendships involved learning. These data therefore challenge the perspective that student groups in higher education are formed and regulated for the primary function of learning. Given these findings, further research is needed to assess the role student friendships play in developing disciplinary conceptual understanding.

  20. Strategies to improve HIV treatment adherence in developed countries: clinical management at the individual level

    Directory of Open Access Journals (Sweden)

    Enriquez M

    2011-05-01

    Full Text Available Maithe Enriquez¹, David S McKinsey²¹School of Nursing, University of Missouri-Kansas City and Division of Infectious Diseases, Truman Medical Center Hospital Hill, ²School of Medicine, Division of Infectious Diseases, University of Kansas and Division of Infectious Diseases, Research Medical Center, Kansas City, MO, USAAbstract: Remarkable advances in the treatment of human immunodeficiency virus (HIV disease have been blunted by widespread suboptimal adherence (ie, nonadherence, which has emerged as a major barrier to achieving the primary goal of antiretroviral (ARV therapy: suppression of HIV viral load. Nonsuppressed HIV viral load is associated with drug resistance, increased morbidity and mortality, and a higher risk of person-to-person HIV transmission. For HIV-infected individuals who are failing HIV treatment due to nonadherence, becoming adherent is a life-saving behavior change. However, overcoming nonadherence is one of the most daunting challenges in the successful management of HIV disease. The purpose of this paper is to provide clinicians with a better understanding of nonadherence to ARV treatment and to review the various factors that have been associated with either adherence or nonadherence. Strategies are presented that may help the nonadherent individual become ready to take HIV medications as prescribed.Keywords: noncompliance, treatment failure, AIDS

  1. Individualized Early Prediction of Familial Risk of Dyslexia: A Study of Infant Vocabulary Development.

    Science.gov (United States)

    Chen, Ao; Wijnen, Frank; Koster, Charlotte; Schnack, Hugo

    2017-01-01

    We examined early vocabulary development in children at familial risk (FR) of dyslexia and typically developing (TD) children between 17 and 35 months of age. We trained a support vector machine to classify TD and FR using these vocabulary data at the individual level. The Dutch version of the McArthur-Bates Communicative Development Inventory (Words and Sentences) (N-CDI) was used to measure vocabulary development. We analyzed group-level differences for both total vocabulary as well as lexical classes: common nouns, predicates, and closed class words. The generalizability of the classification model was tested using cross-validation. At the group level, for both total vocabulary and the composites, the difference between TD and FR was most pronounced at 19-20 months, with FRs having lower scores. For the individual prediction, highest cross-validation accuracy (68%) was obtained at 19-20 months, with sensitivity (correctly classified FR) being 70% and specificity (correctly classified TD) being 67%. There is a sensitive window in which the difference between FR and TD is most evident. Machine learning methods are promising techniques for separating FR and TD children at an early age, before they start reading.

  2. Development of Communication Strategies for the Marketing of Electronic Banking Services for Individuals

    Directory of Open Access Journals (Sweden)

    Dunas Natalia V.

    2017-03-01

    Full Text Available The main aim of the article is to study the trends in the development of communication strategies for the marketing of electronic banking services for individuals by studying the foreign experience in Digital Banking, as well as the situation in the Ukrainian banking market. There offered a comparative characteristic of banking systems of electronic banking services for clients with the purpose of working out flexible methodological approaches for the development of marketing communication strategies for remote client servicing. The characteristic features of electronic banking services and technologies in Ukraine are determined. Comparative evaluation of positive aspects and risks of remote electronic banking systems for banks as well as their client segment is conducted. Analytical aspects of the sociological survey of European banks regarding the selection of the most important priorities of the marketing strategies of financial institutions for 2017 are presented. Also the main factors determining the development of marketing communications of banks and their clients in the field of electronic payments both in Ukraine and abroad are identified. Modern directions of development of communication strategies of marketing of electronic banking services for individuals in Ukraine are proposed.

  3. Crossing the river: Developing a strategy to support understanding of uncertainty within probabilistic climate projections.

    Science.gov (United States)

    Walton, P.; Lamb, R.

    2010-09-01

    The UK Climate Impacts Programme (UKCIP) was established by government in 1997 to support the UK's engagement with becoming better adapted to a changing climate. As the lead organisation in the UK on climate change adaptation, UKCIP oversaw the development of the UK Climate Projections (UKCP09) which were launched in June 2009 providing, for the first time, probabilistic climate projections for the UK. As with previous generations of UKCIP climate scenarios, they were freely accessible and intended for a whole spectrum of users, from technical experts to a lay audience. . Prior to the launch of UKCP09 it was acknowledged that users would need support in understanding key concepts, such as the uncertainty inherent in the projections, to be able to use them appropriately. The user support strategy was therefore developed. It is founded on robust pedagogical principles and draws on the latest thinking on public understanding of science (PUS) that places the user at the centre of the communication process. The adopted approach first identifies profiles of the key users of the climate projections and the ways in which they would use and access the data. Based on these profiles it is possible to identify a range of mechanisms that allow the user to engage with understanding the projections in different ways and situations including lectures, workshops and online learning. Within this blended strategy an exercise was developed specifically to support users' understanding of the concept of uncertainty within the probabilistic climate projections. The ‘Crossing the River' exercise encourages the participants to actively consider the nature of information they are using, and how it could be applied in a specific decision. Reflection and discussion are key elements in supporting the users' understanding of the concept and allowing them to apply the principles in the exercise to their own context. Their reflection is facilitated through a range of mechanisms that provide

  4. Development and application of an optogenetic platform for controlling and imaging a large number of individual neurons

    Science.gov (United States)

    Mohammed, Ali Ibrahim Ali

    The understanding and treatment of brain disorders as well as the development of intelligent machines is hampered by the lack of knowledge of how the brain fundamentally functions. Over the past century, we have learned much about how individual neurons and neural networks behave, however new tools are critically needed to interrogate how neural networks give rise to complex brain processes and disease conditions. Recent innovations in molecular techniques, such as optogenetics, have enabled neuroscientists unprecedented precision to excite, inhibit and record defined neurons. The impressive sensitivity of currently available optogenetic sensors and actuators has now enabled the possibility of analyzing a large number of individual neurons in the brains of behaving animals. To promote the use of these optogenetic tools, this thesis integrates cutting edge optogenetic molecular sensors which is ultrasensitive for imaging neuronal activity with custom wide field optical microscope to analyze a large number of individual neurons in living brains. Wide-field microscopy provides a large field of view and better spatial resolution approaching the Abbe diffraction limit of fluorescent microscope. To demonstrate the advantages of this optical platform, we imaged a deep brain structure, the Hippocampus, and tracked hundreds of neurons over time while mouse was performing a memory task to investigate how those individual neurons related to behavior. In addition, we tested our optical platform in investigating transient neural network changes upon mechanical perturbation related to blast injuries. In this experiment, all blasted mice show a consistent change in neural network. A small portion of neurons showed a sustained calcium increase for an extended period of time, whereas the majority lost their activities. Finally, using optogenetic silencer to control selective motor cortex neurons, we examined their contributions to the network pathology of basal ganglia related to

  5. Student-Developed Simulations: Enhancing Cultural Awareness and Understanding Social Determinants of Health.

    Science.gov (United States)

    Cantey, Danette S; Randolph, Schenita D; Molloy, Margory A; Carter, Brigit; Cary, Michael P

    2017-04-01

    National and global initiatives to address the social determinants of health (SDH) are on the rise. On a parallel trajectory, increased cultural awareness is emerging as an integral strategy to improve the understanding of these social contributions to disease states, health inequities, and health disparities. Undergraduate nursing students developed modalities and role-played simulations as a teaching and learning strategy. The simulations demonstrated how nurses assess patients' unique needs and offer support and resources regarding patients' socioeconomic, cultural, and environmental needs. The student-developed simulations were an interactive teaching and learning strategy that offered several benefits, such as improved interpersonal skills, learned specific nursing roles, and improved cultural awareness. Student-developed simulations are an innovative teaching strategy for improving cultural awareness and learning more about SDH. [J Nurs Educ. 2017;56(4):243-246.]. Copyright 2017, SLACK Incorporated.

  6. Understanding Social Situations (USS): A proof-of-concept social-cognitive intervention targeting theory of mind and attributional bias in individuals with psychosis.

    Science.gov (United States)

    Fiszdon, Joanna M; Roberts, David L; Penn, David L; Choi, Kee-Hong; Tek, Cenk; Choi, Jimmy; Bell, Morris D

    2017-03-01

    In this proof-of-concept trial, we examined the feasibility and preliminary efficacy of Understanding Social Situations (USS), a new social-cognitive intervention that targets higher level social-cognitive skills using methods common to neurocognitive remediation, including drill and practice and hierarchically structured training, which may compensate for the negative effects of cognitive impairment on learning. Thirty-eight individuals with schizophrenia spectrum disorders completed the same baseline assessment of cognitive and social-cognitive functioning twice over a 1-month period to minimize later practice effects, then received 7-10 sessions of USS training, and then completed the same assessment again at posttreatment. USS training was well tolerated and received high treatment satisfaction ratings. Large improvements on the USS Skills Test, which contained items similar to but not identical to training stimuli, suggest that we were effective in teaching specific training content. Content gains generalized to improvements on some of the social-cognitive tasks, including select measures of attributional bias and theory of mind. Importantly, baseline neurocognition did not impact the amount of learning during USS (as indexed by the USS Skills Test) or the amount of improvement on social-cognitive measures. USS shows promise as a treatment for higher level social-cognitive skills. Given the lack of relationship between baseline cognition and treatment effects, it may be particularly appropriate for individuals with lower range cognitive function. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  7. Increased rate of force development during periodized maximum strength and power training is highly individual.

    Science.gov (United States)

    Peltonen, Heikki; Walker, Simon; Hackney, Anthony C; Avela, Janne; Häkkinen, Keijo

    2018-03-06

    Maximum strength training induces various improvements in the rate of force development (RFD) on a group level, but no study has investigated inter-individual adaptations in RFD. Fourteen men (28 ± 6 years old) performed the same 10-week maximum strength and then a 10-week power training program. Maximal force and RFD were recorded during maximal isometric leg extension voluntary contractions repeatedly before every 7th training session (2 sessions/week). After the intervention, subjects were retrospectively divided into three groups based on their RFD improvements: (1) improved only during the maximum strength period (MS-responders, + 100 ± 35%), (2) improved only during the power period (P-responders, + 53 ± 27%) or (3) no improvement at all (non-responders, + 3 ± 9%). All groups increased dynamic 1RM equally, but baseline 1RM was greater (p strength training period. MS-responders increased vastus lateralis cross-sectional area (+ 12 ± 9%, p strength period decreased testosterone (- 17 ± 12; 17 ± 22%), FAI ratio (- 12 ± 14; - 21 ± 23%) and testosterone/cortisol ratio (- 17 ± 25; - 31 ± 20%) in MS and P-responders, respectively. During the P-period hormonal levels plateaued. To conclude, periodized strength training induced different inter-individual physiological responses, and thus RFD development may vary between individuals. Therefore, RFD seems to be a useful tool for planning and monitoring strength training programs for individual neuromuscular performance needs.

  8. Experience-Dependent Brain Development as a Key to Understanding the Language System.

    Science.gov (United States)

    Westermann, Gert

    2016-04-01

    An influential view of the nature of the language system is that of an evolved biological system in which a set of rules is combined with a lexicon that contains the words of the language together with a representation of their context. Alternative views, usually based on connectionist modeling, attempt to explain the structure of language on the basis of complex associative processes. Here, I put forward a third view that stresses experience-dependent structural development of the brain circuits supporting language as a core principle of the organization of the language system. In this view, embodied in a recent neuroconstructivist neural network of past tense development and processing, initial domain-general predispositions enable the development of functionally specialized brain structures through interactions between experience-dependent brain development and statistical learning in a structured environment. Together, these processes shape a biological adult language system that appears to separate into distinct mechanism for processing rules and exceptions, whereas in reality those subsystems co-develop and interact closely. This view puts experience-dependent brain development in response to a specific language environment at the heart of understanding not only language development but adult language processing as well. Copyright © 2016 Cognitive Science Society, Inc.

  9. Development of premature children: caregivers' understanding according to the Bioecological Theory

    Directory of Open Access Journals (Sweden)

    Rayla Amaral Lemos

    2015-12-01

    Full Text Available Abstract OBJECTIVE Understanding the conceptions of premature children caregivers on child development and associated factors. METHOD An exploratory-descriptive qualitative study of 12 families with children under three years of age. Interviews were submitted to thematic content analysis, systematized into the categories of Bioecological Theory of Human Development: Process, Person, Context and Time, and in the Functional Development category. RESULTS There are concerns about impairment in the current and future development of a Person/child defined as fragile as a result of premature birth (Time dimension, minimized by the scope of observable competencies such as motor skills. The Context, especially family and health services, and Proximal Processes, described as one-way caregiver interactions, are considered determinants of development. Functional Development is considered a natural consequence and result of education. The support network is crucial, supporting or limiting care. CONCLUSION Concerns about the development mobilize caregivers to stimulate the premature child/person and requests family and healthcare assistance.

  10. Developing a framework to investigate the personal financial management knowledge of individuals

    Directory of Open Access Journals (Sweden)

    Miemie Struwig

    2013-02-01

    Full Text Available This article focuses on the development of a framework for investigating the personal financial management knowledge of individuals. Content analysis is used to derive the components included in the personal financial management requirements framework. The framework developed includes six components, namely basic concepts in personal finances, management of personal finances, risk management, future planning, investing in financial resources and miscellaneous factors. A qualitative validation process revealed that the framework indeed covers what the average South African citizen is required to know about personal financial planning. The real test of this framework will be to use it in developing an instrument to test individuals’ knowledge of personal financial management. This process of empirically testing the framework, using such an instrument, warrants a separate article.

  11. Using a moot to develop students' understanding of human cloning and statutory interpretation.

    Science.gov (United States)

    Pattinson, Shaun D; Kind, Vanessa

    2017-09-01

    This article reports and analyses the method and findings from a 3-year interdisciplinary project investigating how the medium of law can support understanding of socio-scientific issues. Law represents one of the most important means by which society decides and communicates its values. Activities mirroring legal processes therefore have significant potential to inform, inspire and involve school students in exploring the conceptual, social and ethical issues relating to developments in biomedical science. This article focusses on an intervention-style study in which UK-based 16- to 17-year-old students role played a Supreme Court moot, developed by modifying a domestic appeal case concerned with whether the contemporary legislation covered the creation of cloned human embryos. We draw attention to how the science of cloning has been slightly misunderstood by the courts and in science materials provided to UK school students. We argue that moot-centred engagement activities offer great potential for science communication among post-16 students and, despite the limitations of the judicial process for addressing complex socio-scientific issues, such role plays aid development of scientific and sociolegal understanding, as well as enhancing students' self-confidence and argumentation skills.

  12. Understanding of xerostomia and strategies for the development of artificial saliva.

    Science.gov (United States)

    Kho, Hong-Seop

    2014-01-01

    Xerostomia is becoming a major issue in dental and medical clinics with an increase of aged population. Medication is the most common etiology of xerostomia, while the most severe xerostomia generally occurs in patients with a history of head and neck radiotherapy. Xerostomic patients usually suffer from diminished quality of life due to various symptoms and complications. Decreased salivary output is a definite objective sign, but oral mucosal wetness is a more reliable factor for the evaluation of xerostomia. At present there are no effective therapeutic methods for the treatment of xerostomia. Sialogogues may have problematic side effects and their therapeutic effects last only brief duration. Artificial saliva typically does not produce satisfactory results in therapeutic efficacy. Therefore, further research and development of better therapeutic modalities are necessary. The basic concept for the development of ideal and functional artificial saliva is the mimicry of natural human saliva. We need proper candidate molecules and antimicrobial supplements to simulate the rheological and biological properties of human saliva. We also need better understanding of the interactions between the ingredients of artificial saliva themselves and between the ingredients and components of human saliva both in solution and on surface phases. In addition, we need accepted measures to evaluate the efficacy of artificial saliva. In conclusion, for the development of ideal artificial saliva, research based on the understanding of pathophysiology of xerostomia and knowledge about rheological and biological functions of human saliva are necessary.

  13. Genetic approaches to understanding the population-level impact of wind energy development on migratory bats

    Energy Technology Data Exchange (ETDEWEB)

    Vonhof, Maarten J. [Western Michigan Univ., Kalamazoo MI (United States); Russell, Amy L. [Grand Valley State Univ. Allendale, MI (United States)

    2013-09-30

    Documented fatalities of bats at wind turbines have raised serious concerns about the future impacts of increased wind power development on populations of migratory bat species. Yet there is little data on bat population sizes and trends to provide context for understanding the consequences of mortality due to wind power development. Using a large dataset of both nuclear and mitochondrial DNA variation for eastern red bats, we demonstrated that: 1) this species forms a single, panmictic population across their range with no evidence for the historical use of divergent migratory pathways by any portion of the population; 2) the effective size of this population is in the hundreds of thousands to millions; and 3) for large populations, genetic diversity measures and at least one coalescent method are insensitive to even very high rates of population decline over long time scales and until population size has become very small. Our data provide important context for understanding the population-level impacts of wind power development on affected bat species.

  14. Understanding the internet, website design and intranet development: a primer for radiologists.

    Science.gov (United States)

    Perriss, R W; Graham, R N J; Scarsbrook, A F

    2006-05-01

    The internet has become an essential part of daily life for almost all radiologists and yet few fully understand how this works or how best to harness the technology within the workplace. This article will explore the basics of computer networking which has allowed the internet to become a valuable resource. In addition, the process of designing and implementing a website or intranet site for the benefit of radiology departmental administration and education will be discussed. The options of how to develop a website, what to include, and how to achieve this using easy to use, freely available and low-cost software will also be explored.

  15. Understanding the spatial pattern of urban crime: a developing country's perspective

    OpenAIRE

    Umar, F.; Cheshire, J.; Johnson, S.

    2015-01-01

    Much of the published spatial analysis research of crime to date has been focused on Euro-American cities. This paper attempts to provide an insight on how we can better understand the spatial pattern of crime in a typical developing country’s setting. Data were obtained through extensive field mapping, a block environmental inventory (BEI) and a crime victimization survey to generate a GIS-database of the study area. Grid thematic maps (GTM) for different crime types were produced for visual...

  16. Understanding the internet, website design and intranet development: a primer for radiologists

    International Nuclear Information System (INIS)

    Perriss, R.W.; Graham, R.N.J.; Scarsbrook, A.F.

    2006-01-01

    The internet has become an essential part of daily life for almost all radiologists and yet few fully understand how this works or how best to harness the technology within the workplace. This article will explore the basics of computer networking which has allowed the internet to become a valuable resource. In addition, the process of designing and implementing a website or intranet site for the benefit of radiology departmental administration and education will be discussed. The options of how to develop a website, what to include, and how to achieve this using easy to use, freely available and low-cost software will also be explored

  17. Beyond Normal Competencies: Understanding Organisation Designs to Develop and Sustain IT-Related Capabilities

    Directory of Open Access Journals (Sweden)

    Acklesh Prasad

    2013-03-01

    Full Text Available It is apparent that IT resources are important for organisations. It is also clear that organisations unique competencies, their IT-related capabilities, leverage the IT resources uniquely to create and sustain competitive advantage. However, IT resources are dynamic, and evolve at an exponential rate. This means that organisations will need to sustain their competencies to leverage opportunities offered by new IT resources. Research on ways to sustain IT-related capabilities is limited and a deeper understanding of this situation is important. Amongst other factors, a possible reason for this lack of progress in this area could be due to the lack of validated measurement items of the theoretical constructs to conduct such studies. We suggest an environment in which organisations could build new and sustain their existing IT-related capabilities. We then report on the development of valid and reliable measures for this environment. The validated measures would be useful in extending our understanding on how firms could sustain their IT-related capabilities. This effort will provide a deeper understanding of how firms can secure sustainable IT-related business value from their acquired IT resources.

  18. What the Dynamic Systems Approach Can Offer for Understanding Development: An Example of Mid-childhood Reaching.

    Science.gov (United States)

    Golenia, Laura; Schoemaker, Marina M; Otten, Egbert; Mouton, Leonora J; Bongers, Raoul M

    2017-01-01

    The Dynamic Systems Approach (DSA) to development has been shown to be a promising theory to understand developmental changes. In this perspective, we use the example of mid-childhood (6- to 10-years of age) reaching to show how using the DSA can advance the understanding of development. Mid-childhood is an important developmental period that has often been overshadowed by the focus on the acquisition of reaching during infancy. This underrepresentation of mid-childhood studies is unjustified, as earlier studies showed that important developmental changes in mid-childhood reaching occur that refine the skill of reaching. We review these studies here for the first time and show that different studies revealed different developmental trends, such as non-monotonic and linear trends, for variables such as movement time and accuracy at target. Unfortunately, proposed explanations for these developmental changes have been tailored to individual studies, limiting their scope. Also, explanations were focused on a single component or process in the system that supposedly causes developmental changes. Here, we propose that the DSA can offer an overarching explanation for developmental changes in this research field. According to the DSA, motor behavior emerges from interactions of multiple components entailed by the person, environment, and task. Changes in all these components can potentially contribute to the emerging behavior. We show how the principles of change of the DSA can be used as an overarching framework by applying these principles not only to development, but also the behavior itself. This underlines its applicability to other fields of development.

  19. CO2 emissions from developing countries: Better understanding the role of energy in the long term

    International Nuclear Information System (INIS)

    Sathaye, J.; Goldman, N.

    1991-07-01

    Recent years have witnessed a growing recognition of the link between emissions of carbon dioxide (CO 2 ) and changes in the global climate. Of all anthropogenic activities, energy production and use generate the single largest portion of these greenhouse gases. Although developing countries currently account for a small share of global carbon emissions, their contribution is increasing rapidly. Due to the rapid expansion of energy demand in these nations, the developing world's share in global modern energy use rose from 16 to 27 percent between 1970 and 1990. If the growth rates observed over the past 20 years persist, energy demand in developing nations will surpass that in the countries of the Organization for Economic Cooperation and Development (OECD) early in the 21st century. The study seeks to examine the forces that galvanize the growth of energy use and carbon emissions, to assess the likely future levels of energy and Co 2 in selected developing nations and to identify opportunities for restraining this growth. The purpose of this report is to provide the quantitative information needed to develop effective policy options, not to identify the options themselves. These individual studies were conducted for China, India, Indonesia and South Korea in Asia

  20. CO2 emissions from developing countries: Better understanding the role of Energy in the long term

    International Nuclear Information System (INIS)

    Ketoff, A.; Sathaye, J.; Goldman, N.

    1991-07-01

    Recent years have witnessed a growing recognition of the link between emissions of carbon dioxide (CO 2 ) and changes in the global climate. Of all anthropogenic activities, energy production and use generate the single largest portion of these greenhouse gases. Although developing countries currently account for a small share of global carbon emissions, their contribution is increasing rapidly. Due to the rapid expansion of energy demand in these nations, the developing world's share in global modern energy use rose from 16 to 27 percent between 1970 and 1990. If the growth rates observed over the past 20 years persist energy demand in developing will surpass that in the countries of the Organization for Economic Cooperation and Development (OECD) early in the 21st century. The study seeks to examine the forces that galvanize the growth of energy use and carbon emissions, to assess the likely future levels of energy and CO 2 in selected developing nations and to identify opportunities for restraining this growth. The purpose of this report is to provide the quantitative information needed to develop effective policy options, not to identify the options themselves. These individual studies were conducted fro Argentina, Brazil, Mexico and Venezuela in Latin America

  1. Individualized prediction of perineural invasion in colorectal cancer: development and validation of a radiomics prediction model.

    Science.gov (United States)

    Huang, Yanqi; He, Lan; Dong, Di; Yang, Caiyun; Liang, Cuishan; Chen, Xin; Ma, Zelan; Huang, Xiaomei; Yao, Su; Liang, Changhong; Tian, Jie; Liu, Zaiyi

    2018-02-01

    To develop and validate a radiomics prediction model for individualized prediction of perineural invasion (PNI) in colorectal cancer (CRC). After computed tomography (CT) radiomics features extraction, a radiomics signature was constructed in derivation cohort (346 CRC patients). A prediction model was developed to integrate the radiomics signature and clinical candidate predictors [age, sex, tumor location, and carcinoembryonic antigen (CEA) level]. Apparent prediction performance was assessed. After internal validation, independent temporal validation (separate from the cohort used to build the model) was then conducted in 217 CRC patients. The final model was converted to an easy-to-use nomogram. The developed radiomics nomogram that integrated the radiomics signature and CEA level showed good calibration and discrimination performance [Harrell's concordance index (c-index): 0.817; 95% confidence interval (95% CI): 0.811-0.823]. Application of the nomogram in validation cohort gave a comparable calibration and discrimination (c-index: 0.803; 95% CI: 0.794-0.812). Integrating the radiomics signature and CEA level into a radiomics prediction model enables easy and effective risk assessment of PNI in CRC. This stratification of patients according to their PNI status may provide a basis for individualized auxiliary treatment.

  2. Understanding Democracy and Development Traps Using a Data-Driven Approach.

    Science.gov (United States)

    Ranganathan, Shyam; Nicolis, Stamatios C; Spaiser, Viktoria; Sumpter, David J T

    2015-03-01

    Methods from machine learning and data science are becoming increasingly important in the social sciences, providing powerful new ways of identifying statistical relationships in large data sets. However, these relationships do not necessarily offer an understanding of the processes underlying the data. To address this problem, we have developed a method for fitting nonlinear dynamical systems models to data related to social change. Here, we use this method to investigate how countries become trapped at low levels of socioeconomic development. We identify two types of traps. The first is a democracy trap, where countries with low levels of economic growth and/or citizen education fail to develop democracy. The second trap is in terms of cultural values, where countries with low levels of democracy and/or life expectancy fail to develop emancipative values. We show that many key developing countries, including India and Egypt, lie near the border of these development traps, and we investigate the time taken for these nations to transition toward higher democracy and socioeconomic well-being.

  3. Understanding Democracy and Development Traps Using a Data-Driven Approach

    Science.gov (United States)

    Ranganathan, Shyam; Nicolis, Stamatios C.; Spaiser, Viktoria; Sumpter, David J.T.

    2015-01-01

    Abstract Methods from machine learning and data science are becoming increasingly important in the social sciences, providing powerful new ways of identifying statistical relationships in large data sets. However, these relationships do not necessarily offer an understanding of the processes underlying the data. To address this problem, we have developed a method for fitting nonlinear dynamical systems models to data related to social change. Here, we use this method to investigate how countries become trapped at low levels of socioeconomic development. We identify two types of traps. The first is a democracy trap, where countries with low levels of economic growth and/or citizen education fail to develop democracy. The second trap is in terms of cultural values, where countries with low levels of democracy and/or life expectancy fail to develop emancipative values. We show that many key developing countries, including India and Egypt, lie near the border of these development traps, and we investigate the time taken for these nations to transition toward higher democracy and socioeconomic well-being. PMID:26487983

  4. Some considerations on the development of individual work plan for teachers of Technical and Vocational Education

    Directory of Open Access Journals (Sweden)

    Carlos Alberto Gato Armas

    2010-03-01

    Full Text Available This article analyzes, from the optics of upgrading Technical and Professional Education chief staff in the province and professors in the Technical Sciences Faculty in the University of Pedagogical Sciencies “Rafael María of Mendive” in Pinar del Río, which can facilitate the elaboration of the plan for teachers’ individual work, so that it facilitates the assessment and performance of the planned activities, and at the same time, propitiating the professional development of the teachers, in each school term.

  5. Mentoring to develop research selfefficacy, with particular reference to previously disadvantaged individuals

    OpenAIRE

    S. Schulze

    2010-01-01

    The development of inexperienced researchers is crucial. In response to the lack of research self-efficacy of many previously disadvantaged individuals, the article examines how mentoring can enhance the research self-efficacy of mentees. The study is grounded in the self-efficacy theory (SET) – an aspect of the social cognitive theory (SCT). Insights were gained from an in-depth study of SCT, SET and mentoring, and from a completed mentoring project. This led to the formulation of three basi...

  6. Development and characterization of two-component albedo based neutron individual monitoring system using thermoluminescent detectors

    International Nuclear Information System (INIS)

    Martins, Marcelo Marques

    2008-01-01

    A TLD-albedo based two-component neutron individual monitoring system was developed and characterized in this work. The monitor consists of a black plastic holder, an incident neutron boron loaded shield, a moderator polyethylene body (to increase its response), two pairs of TLD-600 and TLD-700 (one pair to each component) and an adjustable belt. This monitoring system was calibrated in thermal neutron fields and in 70 keV, 144 keV, 565 keV, 1.2 MeV and 5 MeV monoenergetic neutron fields. In addition, it was calibrated in 252C f(D 2 O), 252 Cf, 241 Am-B, 241 Am-Be and 238 Pu-Be source fields. For the latter, the lower detection levels are, respectively, 0.009 mSv, 0.06 mSv, 0.12 mSv, 0.09 mSv and 0.08 mSv. The participation in an international intercomparison sponsored by IAEA with simulated workplace fields validated the system. The monitoring system was successfully characterized in the ISO 21909 standard and in an IRD - the Brazilian Institute for Radioprotection and Dosimetry - technical regulation draft. Nowadays, the neutron individual system is in use by IRD for whole body individual monitoring of five institutions, which comprehend several activities. (author)

  7. Early development and the emergence of individual differences in behavior among littermates of wild rabbit pups.

    Science.gov (United States)

    Rödel, Heiko G; Bautista, Amando; Roder, Manuel; Gilbert, Caroline; Hudson, Robyn

    2017-05-01

    The ontogeny of associated individual differences in behavior and physiology during early postnatal life, and in particular the emergence of such differences among litter siblings, has been hardly explored in mammals under natural conditions. We studied such within-litter differences in behavior in European rabbit pups Oryctolagus cuniculus prior to weaning, and whether and how these differences co-varied with other individual characteristics such as postnatal body temperature and early growth. The study was conducted under semi-natural conditions in a colony of rabbits of wild origin, where the young were born and developed in nursery burrows. We equipped two siblings per litter with interscapular skin temperature loggers on postnatal day 2 and recorded temperature profiles for 48h. Individual body (skin) temperatures of pups within litters were repeatable across time, indicating the existence of consistent individual differences. Such differences within litters were associated with relative differences in pre-weaning growth, revealing that relatively warmer pups showed a greater increase in body mass during the nest period. Between postnatal days 12 and 17, after the pups had reached a developmental stage of greater mobility, we carried out different behavioral tests: a handling-restraint test, an open field test and a jump-down test from a platform. Individual responses in the former two tests were associated, as those pups showing a quicker struggling response to restraint during handling also exhibited greater exploratory activity in the open field. This correlation across contexts suggests the existence of personality types in wild rabbits at an early developmental stage. Furthermore, pups' behavioral responses were strongly associated with their relative within-litter body mass at testing. Animals with a lower body mass compared to their siblings showed a relatively quicker struggle response to handling restraint and covered a relatively larger distance in

  8. Development and Validation of a Prediction Model to Estimate Individual Risk of Pancreatic Cancer.

    Science.gov (United States)

    Yu, Ami; Woo, Sang Myung; Joo, Jungnam; Yang, Hye-Ryung; Lee, Woo Jin; Park, Sang-Jae; Nam, Byung-Ho

    2016-01-01

    There is no reliable screening tool to identify people with high risk of developing pancreatic cancer even though pancreatic cancer represents the fifth-leading cause of cancer-related death in Korea. The goal of this study was to develop an individualized risk prediction model that can be used to screen for asymptomatic pancreatic cancer in Korean men and women. Gender-specific risk prediction models for pancreatic cancer were developed using the Cox proportional hazards model based on an 8-year follow-up of a cohort study of 1,289,933 men and 557,701 women in Korea who had biennial examinations in 1996-1997. The performance of the models was evaluated with respect to their discrimination and calibration ability based on the C-statistic and Hosmer-Lemeshow type χ2 statistic. A total of 1,634 (0.13%) men and 561 (0.10%) women were newly diagnosed with pancreatic cancer. Age, height, BMI, fasting glucose, urine glucose, smoking, and age at smoking initiation were included in the risk prediction model for men. Height, BMI, fasting glucose, urine glucose, smoking, and drinking habit were included in the risk prediction model for women. Smoking was the most significant risk factor for developing pancreatic cancer in both men and women. The risk prediction model exhibited good discrimination and calibration ability, and in external validation it had excellent prediction ability. Gender-specific risk prediction models for pancreatic cancer were developed and validated for the first time. The prediction models will be a useful tool for detecting high-risk individuals who may benefit from increased surveillance for pancreatic cancer.

  9. Understanding the Role of the Immune System in the Development of Cancer: New Opportunities for Population-Based Research.

    Science.gov (United States)

    Michaud, Dominique S; Houseman, E Andres; Marsit, Carmen J; Nelson, Heather H; Wiencke, John K; Kelsey, Karl T

    2015-12-01

    Understanding the precise role of the immune system in cancer has been hindered by the complexity of the immune response and challenges in measuring immune cell types in health and disease in the context of large epidemiologic studies. In this review, we present the rationale to study immunity in cancer and highlight newly available tools to further elucidate the epidemiologic factors driving individual variation in the immune response in cancer. Here, we summarize key studies that have evaluated the role of immunologic status on risk of cancer, discuss tools that have been used in epidemiologic studies to measure immune status, as well as new evolving methodologies where application to epidemiology is becoming more feasible. We also encourage further development of novel emerging technologies that will continue to enable prospective assessment of the dynamic and complex role played by the immune system in cancer susceptibility. Finally, we summarize characteristics and environmental factors that affect the immune response, as these will need to be considered in epidemiologic settings. Overall, we consider the application of a systems biologic approach and highlight new opportunities to understand the immune response in cancer risk. ©2015 American Association for Cancer Research.

  10. A translational neuroscience approach to understanding the development of social anxiety disorder and its pathophysiology.

    Science.gov (United States)

    Fox, Andrew S; Kalin, Ned H

    2014-11-01

    This review brings together recent research from molecular, neural circuit, animal model, and human studies to help understand the neurodevelopmental mechanisms underlying social anxiety disorder. Social anxiety disorder is common and debilitating, and it often leads to further psychopathology. Numerous studies have demonstrated that extremely behaviorally inhibited and temperamentally anxious young children are at marked risk of developing social anxiety disorder. Recent work in human and nonhuman primates has identified a distributed brain network that underlies early-life anxiety including the central nucleus of the amygdala, the anterior hippocampus, and the orbitofrontal cortex. Studies in nonhuman primates have demonstrated that alterations in this circuit are trait-like in that they are stable over time and across contexts. Notably, the components of this circuit are differentially influenced by heritable and environmental factors, and specific lesion studies have demonstrated a causal role for multiple components of the circuit. Molecular studies in rodents and primates point to disrupted neurodevelopmental and neuroplastic processes within critical components of the early-life dispositional anxiety neural circuit. The possibility of identifying an early-life at-risk phenotype, along with an understanding of its neurobiology, provides an unusual opportunity to conceptualize novel preventive intervention strategies aimed at reducing the suffering of anxious children and preventing them from developing further psychopathology.

  11. Recent advances in understanding lung function development [version 1; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Erik Melén

    2017-05-01

    Full Text Available Recent years have witnessed critical contributions to our understanding of the determinants and long-term implications of lung function development. In this article, we review studies that have contributed to advances in understanding lung function development and its critical importance for lung health into adult life. In particular, we have focused on early life determinants that include genetic factors, perinatal events, environmental exposures, lifestyle, infancy lower respiratory tract infections, and persistent asthma phenotypes. Longitudinal studies have conclusively demonstrated that lung function deficits that are established by school age may track into adult life and increase the risk of adult lung obstructive diseases, such as chronic obstructive pulmonary disease. Furthermore, these contributions have provided initial evidence in support of a direct influence by early life events on an accelerated decline of lung function and an increased susceptibility to its environmental determinants well into adult life. As such, we argue that future health-care programs based on precision medicine approaches that integrate deep phenotyping with tailored medication and advice to patients should also foster optimal lung function growth to be fully effective.

  12. Understanding global health and development partnerships: Perspectives from African and global health system professionals.

    Science.gov (United States)

    Barnes, Amy; Brown, Garrett W; Harman, Sophie

    2016-06-01

    Partnership is a key idea in current debates about global health and development assistance, yet little is known about what partnership means to those who are responsible for operationalising it or how it is experienced in practice. This is particularly the case in the context of African health systems. This paper explores how health professionals working in global health hubs and the health systems of South Africa, Tanzania and Zambia understand and experience partnership. Drawing on semi-structured interviews with 101 professionals based in each country, Washington DC and Geneva between October 2012 and June 2013, the paper makes four key arguments. First, partnership has a legitimating function in global health policy processes for international development institutions, government agencies and civil society organisations alike. Second, the practice of partnership generates idiosyncratic and complicated relationships that health professionals have to manage and navigate, often informally. Third, partnership is shaped by historical legacies, critical events, and independent consultants. Fourth, despite being an accepted part of global health policy, there is little shared understanding of what good partnership is meant to include or resemble in practice. Knowing more about the specific socio-cultural and political dynamics of partnership in different health system contexts is critical to equip health professionals with the skills to build the informal relations that are essential to effective partnership engagement. Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. A new method of analysis enabled a better understanding of clinical practice guideline development processes.

    Science.gov (United States)

    Moreira, Tiago; May, Carl; Mason, James; Eccles, Martin

    2006-11-01

    To describe the process by which various forms of evidence are discussed, valued, and interpreted within the process of developing evidence-based clinical practice guidelines and, in so doing, to develop a method for such studies. An observational study. Two guideline development groups were observed by a nonparticipant observer. The 21 meetings were recorded, transcribed, and analyzed using grounded theory and frame analysis. Qualitative analysis was complemented with descriptive statistics. The groups organized their discussion around four domains--'science', 'practice', politics', and 'process'--and used boundary work to mediate between these domains. Both groups spent most time discussing 'science', followed by 'practice' or its relation with 'science'. Our analysis offers an innovative, replicable method of analysis of guideline development that permits the identification of the proportions and interrelations between knowledge domains deployed by guideline groups. This analysis also suggests that the participation hierarchy observed here and by others might be an effect of the imbalanced use of knowledge domains in the construction of clinical guidance. This constitutes an important framework to understand the interplay of participants and knowledge in guideline development.

  14. The Biofuels Revolution: Understanding the Social, Cultural and Economic Impacts of Biofuels Development on Rural Communities

    Energy Technology Data Exchange (ETDEWEB)

    Selfa, Theresa L; Goe, Richard; Kulcsar, Laszlo; Middendorf, Gerad; Bain, Carmen

    2013-02-11

    The aim of this research was an in-depth analysis of the impacts of biofuels industry and ethanol plants on six rural communities in the Midwestern states of Kansas and Iowa. The goal was to provide a better understanding of the social, cultural, and economic implications of biofuels development, and to contribute to more informed policy development regarding bioenergy.Specific project objectives were: 1. To understand how the growth of biofuel production has affected and will affect Midwestern farmers and rural communities in terms of economic, demographic, and socio-cultural impacts; 2. To determine how state agencies, groundwater management districts, local governments and policy makers evaluate or manage bioenergy development in relation to competing demands for economic growth, diminishing water resources, and social considerations; 3. To determine the factors that influence the water management practices of agricultural producers in Kansas and Iowa (e.g. geographic setting, water management institutions, competing water-use demands as well as producers attitudes, beliefs, and values) and how these influences relate to bioenergy feedstock production and biofuel processing; 4. To determine the relative importance of social-cultural, environmental and/or economic factors in the promotion of biofuels development and expansion in rural communities; The research objectives were met through the completion of six detailed case studies of rural communities that are current or planned locations for ethanol biorefineries. Of the six case studies, two will be conducted on rural communities in Iowa and four will be conducted on rural communities in Kansas. A multi-method or mixed method research methodology was employed for each case study.

  15. Development of the isotopic analysis of individual macroparticles: a study of desert dust and interplanetary dust

    International Nuclear Information System (INIS)

    Aleon, Jerome

    2001-01-01

    During this thesis a new analytical technique has been developed to allow the determination of isotopic ratios in microparticles. This technique is based on the imaging properties of the IMS 1270 ion microprobe in CRPG in Nancy. The development of quantitative isotopic imaging allows the determination of the 18 O/ 16 O ratio of individual macroparticles having a size < 2 μm with a 3 to 4 % precision and to map, with ∼ 1 μm lateral resolution, the isotopic variation of hydrogen in particles having a size of 10 μm. This new technique was used to study the problem of the origin of Saharan dust particles, indeed the distribution of 18 O/ 16 O ratios in individual quartz grains is shown to be a characteristic fingerprint of the geology of the source area. The determination of oxygen isotopic ratio in individual grains of a given dust storm above the Atlantic Ocean indicates that the likely source area of this storm is the Air-Tenere region. This result has strong implications for the cycle of Saharan dust in the atmosphere and the processes of dust suspension into the atmosphere. Mapping the D/H variations in 4 interplanetary dust particles collected in the stratosphere by the NASA shows that these particles contain several distinct types of organic matter having an interstellar origin. These organic matters can be related to polymers measured in cornets and carbonaceous chondrites. The presence of these different polymers inside one single particle suggests that the most primitive materials of the solar system may be related to each other. (author) [fr

  16. State and Trait Effects on Individual Differences in Children's Mathematical Development

    Science.gov (United States)

    Bailey, Drew H.; Watts, Tyler W.; Littlefield, Andrew K.; Geary, David C.

    2015-01-01

    Substantial longitudinal relations between children's early mathematics achievement and their much later mathematics achievement are firmly established. These findings are seemingly at odds with studies showing that early educational interventions have diminishing effects on children's mathematics achievement across time. We hypothesized that individual differences in children's later mathematical knowledge are more an indicator of stable, underlying characteristics related to mathematics learning throughout development than of direct effects of early mathematical competency on later mathematical competency. We tested this hypothesis in two longitudinal data sets, by simultaneously modeling effects of latent traits (stable characteristics that influence learning across time) and states (e.g., prior knowledge) on children's mathematics achievement over time. Latent trait effects on children's mathematical development were substantially larger than state effects. Approximately 60% of the variance in trait mathematics achievement was accounted for by commonly used control variables, such as working memory, but residual trait effects remained larger than state effects. Implications for research and practice are discussed. PMID:25231900

  17. Development of a gesture and voice controlled system for burn injury prevention in individuals with disabilities.

    Science.gov (United States)

    Swanepoel, Liam; van den Heever, Dawie; Dellimore, Kiran

    2017-07-01

    Burn injury is a major public health issue in developing countries, with most injuries being largely associated with the use of kitchen stoves. This study details the development of a cost-effective gesture and voice recognition controlled (GVC) system to be used by individuals with disabilities to reduce the likelihood of burn injury and improve their quality of life. The device replaces conventional dial controls with voice and hand gesture recognition sensors and software which are designed to be easily implemented into a household kitchen. Preliminary evaluation of the GVC system's performance in gesture and voice recognition, gas leak detection and ignition control tests were conducted using a Bunsen burner as a stove top surrogate. The voice and gesture recognition tests yielded sensitivities of 88% and 100%, respectively. These results suggest that the GVC system may be a promising solution for burn injury prevention pending further work to improve its reliability and robustness.

  18. Individual Microentrepreneurs: A Study of Their Actions and Perceptions in Response to the Requirements of Sustainable Development

    Directory of Open Access Journals (Sweden)

    Nilton dos Santos Portugal

    2017-05-01

    Full Text Available This paper describes the actions and perceptions of small individual entrepreneurs and is justified by the socioeconomic importance of this new business characterization and the projection of the growth of its formalization, which depicts figures and percentages of significant contribution to the development of the country. In order to understand the sustainable management standards, the study was characterized as descriptive, quantitative, opting for the survey, with the application of structured questionnaires in a sample of 391 entrepreneurs in the micro region of Varginha (MG. From the results it was possible to show a low involvement of small individual entrepreneurs with social and environmental issues. They showed a lack of guidelines aimed at environmental preservation and a lack of interest in volunteering. However, perceptions of the adoption of actions aimed at preserving the environment being able to ensure better living conditions for future generations were frequent; so were the belief that attitudes towards the improvement and welfare of the human being may provide advantages for the company.

  19. The Set of Fear Inducing Pictures (SFIP): Development and validation in fearful and nonfearful individuals.

    Science.gov (United States)

    Michałowski, Jarosław M; Droździel, Dawid; Matuszewski, Jacek; Koziejowski, Wojtek; Jednoróg, Katarzyna; Marchewka, Artur

    2017-08-01

    Emotionally charged pictorial materials are frequently used in phobia research, but no existing standardized picture database is dedicated to the study of different phobias. The present work describes the results of two independent studies through which we sought to develop and validate this type of database-a Set of Fear Inducing Pictures (SFIP). In Study 1, 270 fear-relevant and 130 neutral stimuli were rated for fear, arousal, and valence by four groups of participants; small-animal (N = 34), blood/injection (N = 26), social-fearful (N = 35), and nonfearful participants (N = 22). The results from Study 1 were employed to develop the final version of the SFIP, which includes fear-relevant images of social exposure (N = 40), blood/injection (N = 80), spiders/bugs (N = 80), and angry faces (N = 30), as well as 726 neutral photographs. In Study 2, we aimed to validate the SFIP in a sample of spider, blood/injection, social-fearful, and control individuals (N = 66). The fear-relevant images were rated as being more unpleasant and led to greater fear and arousal in fearful than in nonfearful individuals. The fear images differentiated between the three fear groups in the expected directions. Overall, the present findings provide evidence for the high validity of the SFIP and confirm that the set may be successfully used in phobia research.

  20. FUTURE MUSIC TEACHERS’ PROFESSIONAL AND INDIVIDUAL DEVELOPMENT WHILE STUDYING CONDUCTING AND CHORAL DISCIPLINES

    Directory of Open Access Journals (Sweden)

    Alla Kozyr

    2017-04-01

    Full Text Available The article deals with the problem of professional and individual development of Art Institute students. The aim of the article is to disclose the effectiveness of organising future music teachers’ methodological training which causes their professional and individual development. There is an urgent necessity of implementing integrated knowledge system in musical and pedagogical education which requires greater coordination of the disciplines. The article gives a detailed analysis of future music teachers ‘theoretic and methodological training in the course of conducting and choral disciplines that takes place during the whole period of studying at Art Institutes and at Music and Pedagogics Faculties of Pedagogical Universities. The author claims that the course of conducting and choral disciplines helps overcome drawbacks of future teachers’ training to practice. But this course should be combined with vocal and instrumental training, the unity of these components promote to forming performance skills. It is shown that the main task of learning conducting and choral disciplines at Art Institutes and at Music and Pedagogics Faculties of Pedagogical Universities is directing students to the constant acmeological self-development. The basis for this is future teachers’ independent work that is supervised by tutors. Tutors should encourage students to have responsible attitude to the author’s text. The future conductor should have a habit of accurate reading of author’s text which is one of the preconditions of successful performance. In the article much attention is given to getting basic professional skills that involves training the leaders of school choral groups according to the following trends: studying music and theoretical materials thoroughly; mastering conducting techniques; learning vocal and choral technique and methodology of working with the choir. The author concludes that mastering the main professional skills means

  1. Adapting public policy theory for public health research: A framework to understand the development of national policies on global health.

    Science.gov (United States)

    Jones, Catherine M; Clavier, Carole; Potvin, Louise

    2017-03-01

    National policies on global health appear as one way that actors from health, development and foreign affairs sectors in a country coordinate state action on global health. Next to a burgeoning literature in which international relations and global governance theories are employed to understand global health policy and global health diplomacy at the international level, little is known about policy processes for global health at the national scale. We propose a framework of the policy process to understand how such policies are developed, and we identify challenges for public health researchers integrating conceptual tools from political science. We developed the framework using a two-step process: 1) reviewing literature to establish criteria for selecting a theoretical framework fit for this purpose, and 2) adapting Real-Dato's synthesis framework to integrate a cognitive approach to public policy within a constructivist perspective. Our framework identifies multiple contexts as part of the policy process, focuses on situations where actors work together to make national policy on global health, considers these interactive situations as spaces for observing external influences on policy change and proposes policy design as the output of the process. We suggest that this framework makes three contributions to the conceptualisation of national policy on global health as a research object. First, it emphasizes collective action over decisions of individual policy actors. Second, it conceptualises the policy process as organised interactive spaces for collaboration rather than as stages of a policy cycle. Third, national decision-making spaces are opportunities for transferring ideas and knowledge from different sectors and settings, and represent opportunities to identify international influences on a country's global health policy. We discuss two sets of challenges for public health researchers using interdisciplinary approaches in policy research. Copyright

  2. Understanding continuous professional development participation and choice of mid-career general dental practitioners.

    Science.gov (United States)

    Brown, T; Wassif, H S

    2017-02-01

    Participating in continuing professional development (CPD) activities is a requirement for dental practitioners to keep their skills and knowledge up to date. Understanding the ways dental practitioners engage with professional development and the impact on practice is not fully known (Eaton et al. 2011, http://www.gdc-uk.org/Aboutus/policy/Documents/Impact%20Of%20CPD%20In%20Dentistry.pdf). The aim of this study was to gain insights into the ways that dentists reflect on their professional development and what may be influencing their choices. Empirical qualitative data were collected by semi-structured interviewing of five mid-career dentists. Using grounded theory, the data were analysed for themes about CPD choice and participation. Three themes were identified as influences to dentists' choices of CPD with pragmatic considerations of how new learning could benefit their patients and their practices. Dental practitioners were influenced by the requirements of external regulatory bodies which they did not consider to necessarily improve practice. Dentists working in primary care in the UK are undertaking CPD which is influenced by the pragmatic requirements of running a small business and to meet regulatory requirements. In this sample, dentists are not critically reflecting on their education needs when choosing their CPD activity. Protected learning time and organisational feedback and support are recommended as a way to promote more meaningful reflection on learning and to improve professional development. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  3. A database prototype has been developed to help understand costs in photovoltaic systems

    International Nuclear Information System (INIS)

    Moorw, Larry M.

    2000-01-01

    High photovoltaic (PV) system costs hinder market growth. An approach to studying these costs has been developed using a database containing system, component and maintenance information. This data, which is both technical and non-technical in nature, is to be used to identify trends related to costs. A pilot database exists at this time and work is continuing. The results of this work may be used by the data owners to improve their operations with the goal of sharing non-attributable information with the public and industry at large. The published objectives of the DOE PV program are to accelerate the development of PV as a national and global energy option, as well as ensure US technology and global market leadership. The approach to supporting these objectives is to understand what drives costs in PV applications. This paper and poster session describe work-in-progress in the form of a database that will help identify costs in PV systems. In an effort to address DOE's Five-Year PV Milestones, a program was established in the summer of 1999 to study system costs in three PV applications--solar home lighting, water pumping, and grid-tied systems. This work began with a RFQ requesting data from these types of systems. Creating a partnership with industry and other system organizations such as Non-Government Organizations (NGOs) was the approach chosen to maintain a close time to the systems in the field. Nine participants were selected as partners, who provided data on their systems. Two activities are emphasized in this work. For the first, an iterative approach of developing baseline reliability and costs information with the participants was taken. This effort led to identifying typical components in these systems as well as the specific data (metrics) that would be needed in any analysis used to understand total systems costs

  4. Characterising the Development of the Understanding of Human Body Systems in High-School Biology Students--A Longitudinal Study

    Science.gov (United States)

    Snapir, Zohar; Eberbach, Catherine; Ben-Zvi-Assaraf, Orit; Hmelo-Silver, Cindy; Tripto, Jaklin

    2017-01-01

    Science education today has become increasingly focused on research into complex natural, social and technological systems. In this study, we examined the development of high-school biology students' systems understanding of the human body, in a three-year longitudinal study. The development of the students' system understanding was evaluated…

  5. Understanding access and use of technology among youth with first-episode psychosis to inform the development of technology-enabled therapeutic interventions.

    Science.gov (United States)

    Abdel-Baki, Amal; Lal, Shalini; D-Charron, Olivier; Stip, Emmanuel; Kara, Nadjia

    2017-02-01

    Computers, video games and technological devices are part of young people's everyday lives. However, their use in first-episode psychosis (FEP) treatment is rare. The purpose of this study was to better understand the access and use of technology among individuals with FEP, including gaming activities, to inform future development of technology-enabled therapeutic applications. Self-administered survey on use of technological tools in 71 FEP individuals. PCs/laptops were used by all participants; cellphones/smartphones by 92%, consoles by 83% (mainly male and younger participants). Women texted and used social networks more frequently; men played games (mainly action) more often. The younger individuals reported playing games frequently (32% daily) with less use of the Web and social networks (favourite: Facebook). These data will be useful for developing Web-based psychoeducation tools and cognitive remediation video games for youth with FEP. © 2015 Wiley Publishing Asia Pty Ltd.

  6. Understanding the transport properties of metabolites: case studies and considerations for drug development.

    Science.gov (United States)

    Zamek-Gliszczynski, Maciej J; Chu, Xiaoyan; Polli, Joseph W; Paine, Mary F; Galetin, Aleksandra

    2014-04-01

    Recent analyses demonstrated that metabolites are unlikely to contribute significantly to clinical inhibition of cytochrome P450 (P450)-mediated drug metabolism, and that only ∼2% of this type of drug interaction could not be predicted from the parent drug alone. Due to generally increased polarity and decreased permeability, metabolites are less likely to interact with P450s, but their disposition is instead more likely to involve transporters. This commentary presents case studies illustrating the potential importance of transporters as determinants of metabolite disposition, and as sites of drug interactions, which may alter drug efficacy and safety. Many of these examples are hydrophilic phase II conjugates involved in enterohepatic cycling, where modulation of transporter-dependent disposition may alter pharmacokinetics/pharmacodynamics. The case studies suggest that characterization of metabolite disposition, toxicology, and pharmacology should not focus solely on metabolites with appreciable systemic exposure, but should take into consideration major excretory metabolites. A more thorough understanding of metabolite (phase I and II; circulating and excreted) transport properties during drug development may provide an improved understanding of complex drug-drug interactions (DDIs) that can alter drug and/or metabolite systemic and intracellular exposure. Knowledge and capability gaps remain in clinical translation of in vitro and animal data regarding metabolite disposition. To this end, useful experimental and modeling approaches are highlighted. Application of these tools may lead to a better understanding of metabolite victim and perpetrator DDI potential, and ultimately the establishment of approaches for prediction of pharmacodynamic and toxicodynamic consequences of metabolite transport modulation.

  7. Development and Reliability Testing of a Health Action Process Approach Inventory for Physical Activity Participation among Individuals with Schizophrenia.

    Science.gov (United States)

    Arbour-Nicitopoulos, Kelly P; Duncan, Markus; Remington, Gary; Cairney, John; Faulkner, Guy E

    2014-01-01

    Individuals with schizophrenia tend to have high levels of cardiovascular disease and lower physical activity (PA) levels than the general population. Research is urgently required in developing evidence-based behavioral interventions for increasing PA in this population. One model that has been increasingly used to understand the mechanisms underlying PA is the health action process approach (HAPA). The purpose of this study was to adapt and pilot-test a HAPA-based inventory that reliably captures salient, modifiable PA determinants for individuals with schizophrenia. Initially, 12 outpatients with schizophrenia reviewed the inventory and provided verbal feedback regarding comprehension, item relevance, and potential new content. A content analysis framework was used to inform modifications to the inventory. The resultant inventory underwent a quantitative assessment of internal consistency and test-retest reliability. Twenty-five outpatients (M age = 41.5 ± 13.5 years; 64% male) completed the inventory on two separate occasions, 1 week apart. All but two scales showed good internal consistency (Cronbach's α = 0.62-0.98) and test-retest correlations (rs = 0.21-0.96). Preliminary assessment of criterion validity of the HAPA inventory showed significant, large-sized correlations between behavioral intentions and both affective outcome expectancies and task self-efficacy, and small to moderate correlations between self-reported minutes of moderate-to-vigorous PA and the volitional constructs of the HAPA model. These findings provide preliminary support for the reliability and validity of the first-ever inventory for examining theory-based predictors of moderate-to-vigorous PA intentions and behavior among individuals with schizophrenia. Further validation research with this inventory using an objective measure of PA behavior will provide additional support for its psychometric properties within the schizophrenia population.

  8. Exploring student preferences with a Q-sort: the development of an individualized renal physiology curriculum.

    Science.gov (United States)

    Roberts, John K; Hargett, Charles W; Nagler, Alisa; Jakoi, Emma; Lehrich, Ruediger W

    2015-09-01

    Medical education reform is underway, but the optimal course for change has yet to be seen. While planning for the redesign of a renal physiology course at the Duke School of Medicine, the authors used a Q-sort survey to assess students' attitudes and learning preferences to inform curricular change. The authors invited first-year medical students at the Duke School of Medicine to take a Q-sort survey on the first day of renal physiology. Students prioritized statements related to their understanding of renal physiology, learning preferences, preferred course characteristics, perceived clinical relevance of renal physiology, and interest in nephrology as a career. By-person factor analysis was performed using the centroid method. Three dominant factors were strongly defined by learning preferences: "readers" prefer using notes, a textbook, and avoid lectures; "social-auditory learners" prefer attending lectures, interactivity, and working with peers; and "visual learners" prefer studying images, diagrams, and viewing materials online. A smaller, fourth factor represented a small group of students with a strong predisposition against renal physiology and nephrology. In conclusion, the Q-sort survey identified and then described in detail the dominant viewpoints of our students. Learning style preferences better classified first-year students rather than any of the other domains. A more individualized curriculum would simultaneously cater to the different types of learners in the classroom. Copyright © 2015 The American Physiological Society.

  9. Revisiting the 'disaster and development' debate - Toward a broader understanding of macroeconomic risk and resilience.

    Science.gov (United States)

    Mochizuki, Junko; Mechler, Reinhard; Hochrainer-Stigler, Stefan; Keating, Adriana; Williges, Keith

    2014-01-01

    Debate regarding the relationship between socioeconomic development and natural disasters remains at the fore of global discussions, as the potential risk from climate extremes and uncertainty pose an increasing threat to developmental prospects. This study reviews statistical investigations of disaster and development linkages, across topics of macroeconomic growth, public governance and others to identify key challenges to the current approach to macro-level statistical investigation. Both theoretically and qualitatively, disaster is known to affect development through a number of channels: haphazard development, weak institutions, lack of social safety nets and short-termism of our decision-making practices are some of the factors that drive natural disaster risk. Developmental potentials, including the prospects for sustainable and equitable growth, are in turn threatened by such accumulation of disaster risks. However, quantitative evidence regarding these complex causality chains remains contested due to several reasons. A number of theoretical and methodological limitations have been identified, including the use of GDP as a proxy measurement of welfare, issues with natural disaster damage reporting and the adoption of ad hoc model specifications and variables, which render interpretation and cross-comparison of statistical analysis difficult. Additionally, while greater attention is paid to economic and institutional parameters such as GDP, remittance, corruption and public expenditure as opposed to hard-to-quantify yet critical factors such as environmental conditions and social vulnerabilities. These are gaps in our approach that hamper our comprehensive understanding of the disaster-development nexus. Important areas for further research are identified, including recognizing and addressing the data constraints, incorporating sustainability and equity concerns through alternatives to GDP, and finding novel approaches to examining the complex and dynamic

  10. Understanding the development trends of low-carbon energy technologies: A patent analysis

    International Nuclear Information System (INIS)

    Albino, Vito; Ardito, Lorenzo; Dangelico, Rosa Maria; Messeni Petruzzelli, Antonio

    2014-01-01

    Highlights: • Governments’ strategies set important frameworks to develop and sustain low-carbon energy technologies. • Commercial activities play a key role in the low-carbon energy technologies’ development. • The number of patents that are based upon basic research is growing. - Abstract: Eco-innovations are being recognized as fundamental means to foster sustainable development, as well as to create new business opportunities. Nowadays, the eco-innovation concept is gaining ground within both academic and practitioner studies with the attempt to better understand the main dynamics underlying its nature and guide policymakers and companies in supporting its development. This paper contributes to the extant literature on eco-innovation by providing a comprehensive overview of the evolution of a specific type of eco-innovations that are playing a crucial role in the current socio-economic agenda, namely low-carbon energy technologies. Accordingly, we focus our attention on the related patenting activity of different countries and organizations over time, as well as on influencing policy initiatives and events. Hence, we collected 131,661 patents granted at the United States Patent and Trademark Office (U.S.PTO.) between 1971 and 2010, and belonging to the “Nuclear power generation”, “Alternative energy production”, and “Energy conservation” technological classes, as indicated by the International Patent Classification (IPC) Green Inventory. Our findings report the development trends of low-carbon energy technologies, as well as identify major related environmental programs, historical events, and private sector initiatives explaining those trends, hence revealing how these different circumstances have significantly influenced their development over time

  11. Understanding Teacher Perceptions in a Professional Development Program for a Middle Grade Science

    Science.gov (United States)

    Deloney, Dericka B.

    The standards-based framework requires teachers to evaluate and in some cases change their instructional approach to more student-centered and inquiry-based in an effort to help students meet the standards. The rationale for this study was to determine the skills needed for teachers to be effective in a standard-based, problem-based learning (PBL) constructivist classroom. Traditionally, teachers in this school district transitioning from teacher to student-centered classrooms need new skills when implementing this type of instruction. A qualitative case study design served to highlight the research questions for this project study. The participants in this study participated in data collection activities that include a multiple-choice survey, an interview, and the sharing of their PBL units. Artifacts, professional development teaching resources, from the workshop added credence to the survey and interview responses. The findings from each research question addressed the teachers' perception of their understanding and the obstacles of instructional design, development, and implementation the participants encountered. The results of this study indicated that teachers had problems with designing and implementing this instructional strategy due to lack of time and resources. This data assisted the development of district specific PBL sustainable professional development program that could be adaptable to other curriculums and school systems. Social change resulting from this study could include a framework for developing K-12 professional development as well as instructional programs that incorporates PBL curriculum design to enhance the student's inquiry, problem-solving, and decision-making skills that in turn should change their academic achievement and scores on high stakes test in science.

  12. Human development II: We Need an Integrated Theory for Matter, Life and Consciousness to Understand Life and Healing

    Directory of Open Access Journals (Sweden)

    Sören Ventegodt

    2006-01-01

    Full Text Available For almost a decade, we have experimented with supporting the philosophical development of severely ill patients to induce recovery and spontaneous healing. Recently, we have observed a new pattern of extremely rapid, spontaneous healing that apparently can facilitate even the spontaneous remission of cancer and the spontaneous recovery of mental diseases like schizophrenia and borderline schizophrenia. Our working hypothesis is that the accelerated healing is a function of the patient’s brain-mind and body-mind coming closer together due to the development of what we call “deep” cosmology. To understand and describe what happens at a biological level, we have suggested naming the process adult human metamorphosis, a possibility that is opened by the human genome showing full generic equipment for metamorphosis. To understand the mechanistic details in the complicated interaction between consciousness and biology, we need an adequate theory for biological information. In a series of papers, we propose what we call “holistic biology for holistic medicine”. We suggest that a relatively simple model based on interacting wholenesses instead of isolated parts can shed a new light on a number of difficult issues that we need to explain and understand in biology and medicine in order to understand and use metamorphosis in the holistic medical clinic. We aim to give a holistic theoretical interpretation of biological phenomena at large, morphogenesis, evolution, immune system regulation (self-nonself discrimination, brain function, consciousness, and health in particular. We start at the most fundamental problem: what is biological information at the subcellular, cellular, and supracellular levels if we presume that it is the same phenomenon on all levels (using Occam's razor, and how can this be described scientifically? The problems we address are all connected to the information flow in the functioning, living organism: function of the brain

  13. Parental Attitudes, Beliefs, and Understanding of Anxiety (PABUA): Development and Psychometric Properties of a Measure

    Science.gov (United States)

    Wolk, Courtney Benjamin; Caporino, Nicole E.; McQuarrie, Susanna; Settipani, Cara A.; Podell, Jennifer L.; Crawley, Sarah; Beidas, Rinad S.; Kendall, Philip C.

    2016-01-01

    The Parental Attitudes, Beliefs, and Understanding of Anxiety (PABUA) was developed to assess parental beliefs about their child’s anxiety, parents’ perceived ability to cope with their child’s anxiety and to help their child manage anxious symptoms, and to evaluate parents’ understanding of various parenting strategies in response to their child’s anxiety. The study evaluated the PABUA in mother-child dyads (N = 192) seeking treatment for youth anxiety. Exploratory factor analysis yielded a three-factor solution and identified PABUA scales of Overprotection, Distress, and Approach (with Cronbach’s alpha ranging from .67 to .83). Convergent and divergent validity of PABUA scales was supported by the pattern of associations with measures of experiential avoidance, beliefs related to children’s anxiety, empathy, trait anxiety, and depressive symptoms; parent-reported family functioning; parent- and youth-reported anxiety severity; and parent-reported functional impairment (n = 83). Results provide preliminary support for the PABUA as a measure of parental attitudes and beliefs about anxiety, and future studies that investigate this measure with large and diverse samples are encouraged. PMID:26970877

  14. Parental Attitudes, Beliefs, and Understanding of Anxiety (PABUA): Development and psychometric properties of a measure.

    Science.gov (United States)

    Wolk, Courtney Benjamin; Caporino, Nicole E; McQuarrie, Susanna; Settipani, Cara A; Podell, Jennifer L; Crawley, Sarah; Beidas, Rinad S; Kendall, Philip C

    2016-04-01

    The Parental Attitudes, Beliefs, and Understanding of Anxiety (PABUA) was developed to assess parental beliefs about their child's anxiety, parents' perceived ability to cope with their child's anxiety and to help their child manage anxious symptoms, and to evaluate parents' understanding of various parenting strategies in response to their child's anxiety. The study evaluated the PABUA in mother-child dyads (N=192) seeking treatment for youth anxiety. Exploratory factor analysis yielded a three-factor solution and identified PABUA scales of Overprotection, Distress, and Approach (with Cronbach's alpha ranging from .67 to .83). Convergent and divergent validity of PABUA scales was supported by the pattern of associations with measures of experiential avoidance, beliefs related to children's anxiety, empathy, trait anxiety, and depressive symptoms; parent-reported family functioning; parent- and youth-reported anxiety severity; and parent-reported functional impairment (n=83). Results provide preliminary support for the PABUA as a measure of parental attitudes and beliefs about anxiety, and future studies that investigate this measure with large and diverse samples are encouraged. Copyright © 2016 Elsevier Ltd. All rights reserved.

  15. The effect of development and individual differences in pointing comprehension of dogs.

    Science.gov (United States)

    Gácsi, Márta; Kara, Edina; Belényi, Bea; Topál, József; Miklósi, Adám

    2009-05-01

    In spite of the rather different procedures actually used in comparative studies to test the ability of different species to rely on the human pointing gesture, there is no debate on the high performance of dogs in such tasks. Very little is known, however, on the course through which they acquire this ability or the probable factors influencing the process. Important developmental questions have remained unsolved and also some methodological concerns should be addressed before we can convincingly argue for one interpretation or another. In this study we tested 180 dogs of different age (from 2 months to adults) to investigate their performance in the human distal momentary pointing gesture. The results, analyzed at both the group and the individual levels, showed no difference in the performance according to age, indicating that in dogs the comprehension of the human pointing may require only very limited and rapid early learning to fully develop. Interestingly, neither the keeping conditions nor the time spent in active interaction with the owner, and not even some special (agility) training for using human visual cues, had significant effect on the success and explained individual differences. The performance of the dogs was rather stable over time: during the 20 trials within a session and even when subsamples of different age were repeatedly tested. Considering that in spite of the general success at the group level, more than half of the dogs were not successful at the individual level, we revealed alternative "decision-making rules" other than following the pointing gesture of the experimenter.

  16. Thalamic functional connectivity predicts seizure laterality in individual TLE patients: application of a biomarker development strategy.

    Science.gov (United States)

    Barron, Daniel S; Fox, Peter T; Pardoe, Heath; Lancaster, Jack; Price, Larry R; Blackmon, Karen; Berry, Kristen; Cavazos, Jose E; Kuzniecky, Ruben; Devinsky, Orrin; Thesen, Thomas

    2015-01-01

    Noninvasive markers of brain function could yield biomarkers in many neurological disorders. Disease models constrained by coordinate-based meta-analysis are likely to increase this yield. Here, we evaluate a thalamic model of temporal lobe epilepsy that we proposed in a coordinate-based meta-analysis and extended in a diffusion tractography study of an independent patient population. Specifically, we evaluated whether thalamic functional connectivity (resting-state fMRI-BOLD) with temporal lobe areas can predict seizure onset laterality, as established with intracranial EEG. Twenty-four lesional and non-lesional temporal lobe epilepsy patients were studied. No significant differences in functional connection strength in patient and control groups were observed with Mann-Whitney Tests (corrected for multiple comparisons). Notwithstanding the lack of group differences, individual patient difference scores (from control mean connection strength) successfully predicted seizure onset zone as shown in ROC curves: discriminant analysis (two-dimensional) predicted seizure onset zone with 85% sensitivity and 91% specificity; logistic regression (four-dimensional) achieved 86% sensitivity and 100% specificity. The strongest markers in both analyses were left thalamo-hippocampal and right thalamo-entorhinal cortex functional connection strength. Thus, this study shows that thalamic functional connections are sensitive and specific markers of seizure onset laterality in individual temporal lobe epilepsy patients. This study also advances an overall strategy for the programmatic development of neuroimaging biomarkers in clinical and genetic populations: a disease model informed by coordinate-based meta-analysis was used to anatomically constrain individual patient analyses.

  17. Developing and validating a conceptual survey to assess introductory physics students’ understanding of magnetism

    Science.gov (United States)

    Li, Jing; Singh, Chandralekha

    2017-03-01

    Development of validated physics surveys on various topics is important for investigating the extent to which students master those concepts after traditional instruction and for assessing innovative curricula and pedagogies that can improve student understanding significantly. Here, we discuss the development and validation of a conceptual multiple-choice survey related to magnetism suitable for introductory physics courses. The survey was developed taking into account common students’ difficulties with magnetism concepts covered in introductory physics courses found in our investigation and the incorrect choices to the multiple-choice questions were designed based upon those common student difficulties. After the development and validation of the survey, it was administered to introductory physics students in various classes in paper-pencil format before and after traditional lecture-based instruction in relevant concepts. We compared the performance of students on the survey in the algebra-based and calculus-based introductory physics courses before and after traditional lecture-based instruction in relevant magnetism concepts. We discuss the common difficulties of introductory physics students with magnetism concepts we found via the survey. We also administered the survey to upper-level undergraduates majoring in physics and PhD students to benchmark the survey and compared their performance with those of traditionally taught introductory physics students for whom the survey is intended. A comparison with the base line data on the validated magnetism survey from traditionally taught introductory physics courses and upper-level undergraduate and PhD students discussed in this paper can help instructors assess the effectiveness of curricula and pedagogies which is especially designed to help students integrate conceptual and quantitative understanding and develop a good grasp of the concepts. In particular, if introductory physics students’ average

  18. Developing and validating a conceptual survey to assess introductory physics students’ understanding of magnetism

    International Nuclear Information System (INIS)

    Li, Jing; Singh, Chandralekha

    2017-01-01

    Development of validated physics surveys on various topics is important for investigating the extent to which students master those concepts after traditional instruction and for assessing innovative curricula and pedagogies that can improve student understanding significantly. Here, we discuss the development and validation of a conceptual multiple-choice survey related to magnetism suitable for introductory physics courses. The survey was developed taking into account common students’ difficulties with magnetism concepts covered in introductory physics courses found in our investigation and the incorrect choices to the multiple-choice questions were designed based upon those common student difficulties. After the development and validation of the survey, it was administered to introductory physics students in various classes in paper–pencil format before and after traditional lecture-based instruction in relevant concepts. We compared the performance of students on the survey in the algebra-based and calculus-based introductory physics courses before and after traditional lecture-based instruction in relevant magnetism concepts. We discuss the common difficulties of introductory physics students with magnetism concepts we found via the survey. We also administered the survey to upper-level undergraduates majoring in physics and PhD students to benchmark the survey and compared their performance with those of traditionally taught introductory physics students for whom the survey is intended. A comparison with the base line data on the validated magnetism survey from traditionally taught introductory physics courses and upper-level undergraduate and PhD students discussed in this paper can help instructors assess the effectiveness of curricula and pedagogies which is especially designed to help students integrate conceptual and quantitative understanding and develop a good grasp of the concepts. In particular, if introductory physics students’ average

  19. Development of innovative tools for understanding marine biodiversity and assessing good environmental status, within the European Marine Strategy Framework Directive

    Science.gov (United States)

    Borja, Angel; Uyarra, María C.

    2014-05-01

    Marine natural resources and ecosystem services constitute the natural capital that supports economies, societies and individual well-being. Good governance requires a quantification of the interactions and trade-offs among ecosystem services and understanding of how biodiversity underpins ecosystem functions and services across time, scales and sectors. Marine biodiversity is a key descriptor for the assessment within the Marine Strategy Framework Directive (MSFD), approved in 2008, which comprises a total of 11 descriptors. However, the relationships between pressures from human activities and climatic influences and their effects on marine biological diversity are still only partially understood. Hence, these relationships need to be better understood in order to fully achieve a good environmental status (GEnS), as required by the MSFD. This contribution is based upon the FP7 EU project DEVOTES (DEVelopment Of innovative Tools for understanding marine biodiversity and assessing good Environmental Status), which focus on developing innovative conceptual frameworks, methods and coherent, shared protocols to provide consistent datasets and knowledge at different scales, within four regional seas (Black Sea, Mediterranean, Atlantic and Baltic Sea). This project is developing innovative approaches to valuate biodiversity and ecosystem services and to develop public goods and sustainable economic activities from them. The research will benefit sea users and stakeholders, and will contribute to assess and monitor the environmental status of marine waters. The main objectives are: (i) to improve our understanding of the impact of human activities and variations associated to climate on marine biodiversity, (ii) to test indicators (referred in the Commission Decision on GEnS) and develop new ones for assessment at several ecological levels (species, habitat, ecosystems) and for the characterization and status classification of the marine waters, (iii) to develop, test

  20. What enhances the development of emotion understanding in young children? A longitudinal study of interpersonal predictors.

    Science.gov (United States)

    Kårstad, Silja B; Wichstrøm, Lars; Reinfjell, Trude; Belsky, Jay; Berg-Nielsen, Turid S

    2015-09-01

    We studied potential determinants of the development of children's emotion understanding (EU) from age 4 to 6 in a Norwegian community sample (N = 974) using the Test of Emotion Comprehension. Interpersonal predictors included the accuracy of parental mentalization, parental emotional availability, and teacher-reported child social skills. Intrapersonal child factors were child gender and verbal skills. Overall, children's EU increased significantly over time. After adjusting for child gender, age-4 EU, and parental socio-economic status, greater child verbal and social skills and greater parental mentalization each uniquely predicted growth in EU. Results are discussed in terms of theory and research on children's EU and parents' emotion socialization. © 2015 The British Psychological Society.

  1. Development of a Control System for the Teat-End Vacuum in Individual Quarter Milking Systems

    Science.gov (United States)

    Ströbel, Ulrich; Rose-Meierhöfer, Sandra; Öz, Hülya; Brunsch, Reiner

    2013-01-01

    Progress in sensor technique and electronics has led to a decrease in the costs of electronic and sensor components. In modern dairy farms, having udders in good condition, a lower frequency of udder disease and an extended service life of dairy cows will help ensure competitiveness. The objective of this study was to develop a teat-end vacuum control system with individual quarter actor reaction. Based on a review of the literature, this system is assumed to protect the teat tissue. It reduces the mean teat-end vacuum in the maximum vacuum phase (b) to a level of 20 kPa at a flow rate of 0.25 L/min per quarter. At flow rates higher than 1.50 L/min per quarter, the teat-end vacuum can be controlled to a level of 30 kPa, because in this case it is desirable to have a higher vacuum for the transportation of the milk to the receiver. With this system it is possible for the first time to supply the teat end with low vacuum at low flow rates and with higher vacuum at increasing flow rates in a continuous process with a three second reaction-rate on individual quarter level. This system is completely automated. PMID:23765272

  2. Understanding Immune Cells in Tertiary Lymphoid Organ Development: It Is All Starting to Come Together

    Science.gov (United States)

    Jones, Gareth W.; Hill, David G.; Jones, Simon A.

    2016-01-01

    Tertiary lymphoid organs (TLOs) are frequently observed in tissues affected by non-resolving inflammation as a result of infection, autoimmunity, cancer, and allograft rejection. These highly ordered structures resemble the cellular composition of lymphoid follicles typically associated with the spleen and lymph node compartments. Although TLOs within tissues show varying degrees of organization, they frequently display evidence of segregated T and B cell zones, follicular dendritic cell networks, a supporting stromal reticulum, and high endothelial venules. In this respect, they mimic the activities of germinal centers and contribute to the local control of adaptive immune responses. Studies in various disease settings have described how these structures contribute to either beneficial or deleterious outcomes. While the development and architectural organization of TLOs within inflamed tissues requires homeostatic chemokines, lymphoid and inflammatory cytokines, and adhesion molecules, our understanding of the cells responsible for triggering these events is still evolving. Over the past 10–15 years, novel immune cell subsets have been discovered that have more recently been implicated in the control of TLO development and function. In this review, we will discuss the contribution of these cell types and consider the potential to develop new therapeutic strategies that target TLOs. PMID:27752256

  3. UNDERSTANDING HOW HEALTHY WORKPLACES ARE CREATED: IMPLICATIONS FOR DEVELOPING A NATIONAL HEALTH SERVICE HEALTHY WORKPLACE PROGRAM.

    Science.gov (United States)

    Wyatt, Katrina M; Brand, Sarah; Ashby-Pepper, Julie; Abraham, Jane; Fleming, Lora E

    2015-01-01

    The workplace is an important setting for promoting health and well-being. We sought to understand how successful workplace health and well-being programs were developed and implemented to inform the development of a program for a National Health Service (NHS) hospital. Case studies of successful healthy workplace programs with 34 semi-structured employee interviews informed 12 interviews with NHS staff. Interviews were thematically analyzed using Nvivo. Themes were fed back to participants for further clarification and validation. Healthy workplace programs were characterized by senior management endorsement; collective sense of ownership; presence of visible "quick wins"; and a sense that participation was easy and fun, not mandated. Programs evolved organically, allowing trust to be built and activities to be developed with employees. Interviews with NHS staff suggested a lack of belief in the possibility of change in their workplace due to time and workload pressures, and a sense of an "us and them" relationship with management, as well as environmental barriers. A consistent pattern of how the conditions for a healthy workplace can be created, which map onto the results from the NHS ward staff, suggest that without creating an enabling environment for health-promoting behaviors, workplace programs will have poor uptake and retention.

  4. Frogs as integrative models for understanding digestive organ development and evolution.

    Science.gov (United States)

    Womble, Mandy; Pickett, Melissa; Nascone-Yoder, Nanette

    2016-03-01

    The digestive system comprises numerous cells, tissues and organs that are essential for the proper assimilation of nutrients and energy. Many aspects of digestive organ function are highly conserved among vertebrates, yet the final anatomical configuration of the gut varies widely between species, especially those with different diets. Improved understanding of the complex molecular and cellular events that orchestrate digestive organ development is pertinent to many areas of biology and medicine, including the regeneration or replacement of diseased organs, the etiology of digestive organ birth defects, and the evolution of specialized features of digestive anatomy. In this review, we highlight specific examples of how investigations using Xenopus laevis frog embryos have revealed insight into the molecular and cellular dynamics of digestive organ patterning and morphogenesis that would have been difficult to obtain in other animal models. Additionally, we discuss recent studies of gut development in non-model frog species with unique feeding strategies, such as Lepidobatrachus laevis and Eleutherodactylous coqui, which are beginning to provide glimpses of the evolutionary mechanisms that may generate morphological variation in the digestive tract. The unparalleled experimental versatility of frog embryos make them excellent, integrative models for studying digestive organ development across multiple disciplines. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. Using Metasynthesis to Develop Sensitising Concepts to Understand Torres Strait Islander Migration

    Directory of Open Access Journals (Sweden)

    Vinnitta Patricia Mosby

    2013-03-01

    Full Text Available Emerging research indicates that more and more Indigenous peoples will be forced to migrate due to climate change. Current responses focus on mitigation and adaptation strategies. One such group, Torres Strait Islander people are already moving for other reasons and existing vulnerabilities compound levels of disadvantage when moving. It will be important to understand Torres Strait Islander people’s experiences of contemporary movements in order to inform policy development and facilitate the process of migration and resettlement as movement increases. A synthesis of existing studies would allow the development of sensitising concepts that could inform future research in the Torres Strait Islander context. This article presents a metasynthesis of six qualitative studies of the experiences of different Indigenous and minority groups at various stages of migration, displacement and resettlement. Articles were selected on contemporary movements (2001-2011 and importantly the inclusion of first person voice. Reciprocal translation was used to synthesise common themes and a core construct. The overarching construct that became apparent from the metasynthesis was ‘continuity of being’ through staying connected to self, family and culture. Three themes emerged: ‘freedom to be’, ‘staying close’ and ‘forming anchor’. These were enacted through people valuing their personal, social, religious and political freedom and recognising the importance of maintaining or forming strong social and family networks. When researching the experiences of Torres Strait Islanders it will be necessary to focus on motivations for moving, and understand the processes for staying connected to kin and homeland in order to achieve the desired outcomes of successful resettlement under conditions of uncertainty.

  6. Gut microbiota: next frontier in understanding human health and development of biotherapeutics

    Directory of Open Access Journals (Sweden)

    Prakash S

    2011-07-01

    Full Text Available Satya Prakash, Laetitia Rodes, Michael Coussa-Charley, Catherine Tomaro-DuchesneauBiomedical Technology and Cell Therapy Research Laboratory, Department of Biomedical Engineering and Artificial Cells and Organs Research Centre, Faculty of Medicine, McGill University, Montreal, Quebec, CanadaAbstract: The gut microbiota is a remarkable asset for human health. As a key element in the development and prevention of specific diseases, its study has yielded a new field of promising biotherapeutics. This review provides comprehensive and updated knowledge of the human gut microbiota, its implications in health and disease, and the potentials and limitations of its modification by currently available biotherapeutics to treat, prevent and/or restore human health, and future directions. Homeostasis of the gut microbiota maintains various functions which are vital to the maintenance of human health. Disruption of the intestinal ecosystem equilibrium (gut dysbiosis is associated with a plethora of human diseases, including autoimmune and allergic diseases, colorectal cancer, metabolic diseases, and bacterial infections. Relevant underlying mechanisms by which specific intestinal bacteria populations might trigger the development of disease in susceptible hosts are being explored across the globe. Beneficial modulation of the gut microbiota using biotherapeutics, such as prebiotics, probiotics, and antibiotics, may favor health-promoting populations of bacteria and can be exploited in development of biotherapeutics. Other technologies, such as development of human gut models, bacterial screening, and delivery formulations eg, microencapsulated probiotics, may contribute significantly in the near future. Therefore, the human gut microbiota is a legitimate therapeutic target to treat and/or prevent various diseases. Development of a clear understanding of the technologies needed to exploit the gut microbiota is urgently required.Keywords: gut microbiota, human

  7. Grand challenges in developing a predictive understanding of global fire dynamics

    Science.gov (United States)

    Randerson, J. T.; Chen, Y.; Wiggins, E. B.; Andela, N.; Morton, D. C.; Veraverbeke, S.; van der Werf, G.

    2017-12-01

    High quality satellite observations of burned area and fire thermal anomalies over the past two decades have transformed our understanding of climate, ecosystem, and human controls on the spatial and temporal distribution of landscape fires. The satellite observations provide evidence for a rapid and widespread loss of fire from grassland and savanna ecosystems worldwide. Continued expansion of industrial agriculture suggests that observed declines in global burned area are likely to continue in future decades, with profound consequences for ecosystem function and the habitat of many endangered species. Satellite time series also highlight the importance of El Niño-Southern Oscillation and other climate modes as drivers of interannual variability. In many regions, lead times between climate indices and fire activity are considerable, enabling the development of early warning prediction systems for fire season severity. With the recent availability of high-resolution observations from Suomi NPP, Landsat 8, and Sentinel 2, the field of global fire ecology is poised to make even more significant breakthroughs over the next decade. With these new observations, it may be possible to reduce uncertainties in the spatial pattern of burned area by several fold. It is difficult to overstate the importance of these new data constraints for improving our understanding of fire impacts on human health and radiative forcing of climate change. A key research challenge in this context is to understand how the loss of global burned area will affect magnitude of the terrestrial carbon sink and trends in atmospheric composition. Advances in prognostic fire modeling will require new approaches linking agriculture with landscape fire dynamics. A critical need in this context is the development of predictive models of road networks and other drivers of land fragmentation, and a closer integration of fragmentation information with algorithms predicting fire spread. Concurrently, a better

  8. Pathways to Higher Education for Native Hawaiian Individual Development Account Participants

    Directory of Open Access Journals (Sweden)

    David W. Rothwell

    2013-11-01

    Full Text Available As the cost of higher education rises, a growing body of theory and research suggests that asset holding in the form of savings and net worth positively influence education expectations and outcomes. Native Hawaiians, like other Indigenous peoples, have disproportionately low college enrollment and graduation rates tied to a history of colonization. Using data from an Individual Development Account (IDA program for Native Hawaiians, I examine the trajectories through the program and find: (a welfare receipt and unemployment reduces the chances of IDA enrollment; (b net worth increases the probability of IDA graduation; and (c IDA graduates were more likely to gain a college degree over time compared to non-graduates. The study provides empirical evidence to the debate on asset-based interventions for Indigenous peoples.

  9. Developing an Understanding of Vegetation Change and Fluvial Carbon Fluxes in Semi-Arid Environments

    Science.gov (United States)

    Puttock, A.; Brazier, R. E.; Dungait, J. A. J.; Bol, R.; Macleod, C. J. A.

    2012-04-01

    biogeochemical techniques, using stable 13C isotope and lipid biomarker analyses, to trace and partition fluvial soil organic matter and carbon fluxes during these events. Results show that biomarkers specific to individual plant species can be used to define the provenance of carbon, quantifying whether more piñon or juniper derived carbon is mobilised from the upland plots, or whether more Larrea tridentata carbon is lost when compared to Bouteloa eripoda losses in the lowlands. The combined approach of monitoring carbon fluxes and tracing types of carbon shows great promise for improved understanding of carbon dynamics in areas subject to rapid vegetation change.

  10. The response of runoff generation to urban development: modelling and understanding

    Science.gov (United States)

    Guan, Mingfu; Sillanpää, Nora; Koivusalo, Harri

    2014-05-01

    The urbanisation process strongly changes natural catchment by increasing the impervious coverage and by creating a need for efficient drainage systems, resulting in a significant change of catchment hydrology from extreme floods to low flows. Thus, it is becoming important to quantify the impacts of urbanisation on runoff generation and to investigate the possibility of restoring pre-development flows in urban catchments for integrated urban stormwater management. Urban hydrological modelling emphasising on urbanisation effects has received substantial attention. However, the lack of good quality monitoring data in a same developing catchment limits model calibration for many of previous studies. In this concern, this study aims to describe and better understand the effects of urbanisation on catchment hydrology through modelling of a series of scenarios in a developing urban catchment of Saunalahdenranta (SR). The catchment is located at Espoo, southern Finland and has an area of about 13.2 ha. The catchment was developed rapidly from a rural area to a residential area during 2001-2006. Hydrological data were measured in two minutes intervals during the development period, when the imperviousness of the catchment changed from 1.5% to 37%. Precipitation-runoff relationship is simulated using the Stormwater Management Model (SWMM) that is firstly parameterised, calibrated, and validated for the scenario of highly developed residential catchment in 2006. The hydrological impacts of spatial resolution and model parameters, such as the delineation of subcatchment, flow width as well as Manning's roughness are evaluated and discussed. The calibrated model is then used to investigate, how the hydrological response to urbanisation was changing in the scenarios for the previous years (2001-2005) with different levels of urban development (represented by impervious surfaces). The predictions for the several scenarios provide a quantification of the hydrological impacts of

  11. Developing a scale to measure "attachment to the local community" in late middle aged individuals.

    Science.gov (United States)

    Sakai, Taichi; Omori, Junko; Takahashi, Kazuko; Mitsumori, Yasuko; Kobayashi, Maasa; Ono, Wakanako; Miyazaki, Toshie; Anzai, Hitomi; Saito, Mika

    2016-01-01

    Objectives This study was conducted to develop a scale for measuring "attachment to the local community" for its use in health services. The scale is also intended to nurture new social relationships in late middle-aged individuals.Methods Thirty items were initially planned to be included in the scale to measure "attachment to the local community", according to a previous study that identified the concept. The study subjects were late middle-aged residents of City B in Prefecture A, located in Tokyo suburbs. From the basic resident register data, 1,000 individuals (local residents in the 50-69 year age group) were selected by a multi-stage random sampling technique, on the basis of their residential area, age, and sex (while maintaining the male to female ratio). An unsigned self-administered questionnaire was distributed to the subjects, and the responses were collected by postal mail. The collected data was analyzed using psychometric study of scale.Results Valid responses were obtained from 583 subjects, and the response rate was 58.3%. In an item analysis, none of the items were rejected. In a subsequent factor analysis, 7 items were eliminated. These items included 2 items with a factor loading of vitality to live life," "Intention to cherish ties with people," "Place where one can be oneself," and "Pride of being a resident." Cronbach's coefficient α for the entire scale of "attachment to the local community" was 0.95, demonstrating internal consistency. We then examined the correlation with an existing scale to measure social support; the results revealed a statistically significant correlation and confirmed criterion-related validity (P<0.001). In addition, the fit indices in a covariance structure analysis showed adequate values.Conclusions The developed scale was considered reliable and appropriate for measuring "attachment to the local community."

  12. The detrimental effect of interference in multiplication facts storing: typical development and individual differences.

    Science.gov (United States)

    De Visscher, Alice; Noël, Marie-Pascale

    2014-12-01

    The difficulty in memorizing arithmetic facts is a general and persistent hallmark of math learning disabilities. It has recently been suggested that hypersensitivity to interference could prevent a person from storing arithmetic facts. The similarity between arithmetic facts would provoke interference, and learners who are hypersensitive to interference would therefore encounter difficulties in storing arithmetic facts in long-term memory. In this study, we created a measure of the interference weight for each multiplication by measuring the overlap of digits between multiplications. First, we tested whether the interference parameter could predict performance across multiplications by analyzing the data from undergraduates published by Campbell (1997). The interference parameter substantially predicted performance across multiplications. Similarly, the performance across multiplications was substantially determined by the interference parameter in 3rd-grade children, 5th-grade children, and undergraduates we tested. Second, we tested whether people with poor arithmetic facts abilities were particularly sensitive to the interference parameter. We tested this hypothesis in typical development by analyzing the data from the 3rd-grade children, 5th-grade children, and undergraduates. We analyzed data with regard to atypical development from a published case study of dyscalculia as well as from 4th-grade children, with either poor or good multiplication skills, tested twice 1 year apart. Results showed that the individual sensitivity to the interference parameter determined part of the individual differences in multiplication performance in all data sets. These findings show that the learning of multiplications is particularly interference prone because of feature overlap and that people who are sensitive to this parameter therefore encounter difficulties in memorizing arithmetic facts. PsycINFO Database Record (c) 2014 APA, all rights reserved.

  13. New treatments in development for Pseudomonas aeruginosa infections in the lungs of individuals with cystic fibrosis

    Directory of Open Access Journals (Sweden)

    Akh

    2014-10-01

    Full Text Available Saeed S Akhand,1 Rebecca S Pettit,2 Tonia E Gardner,3 Gregory G Anderson1 1Department of Biology, Indiana University–Purdue University Indianapolis, 2Riley Hospital for Children, Indiana University Health, 3Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA Abstract: In 1989, with the discovery of the genetic mutation causing cystic fibrosis (CF, a cure for this terrible disease seemed just around the corner. Though significant progress has been made to improve the quality of life of CF patients, a remedy for CF is yet to be found. Of great concern, such bacteria as Pseudomonas aeruginosa establish chronic infections that are extremely difficult to eradicate. P. aeruginosa thrives in the CF lung environment, where it protects itself from the host inflammatory defense and contributes immensely to the lung inflammation and tissue destruction seen with the disease. Tackling and eradicating P. aeruginosa infection in the CF lung holds the key to lessen the suffering of these individuals. Unfortunately, current antibiotic regimens are insufficient to eliminate P. aeruginosa from the CF lung. In this review, we address recent drugs that are currently under development to eradicate P. aeruginosa infection in the airways of patients with CF. We discuss the P. aeruginosa infection from the perspective of CF, the shortcomings of current drugs, and the upcoming drugs that are under clinical trials and development. These new drugs and therapies hold much promise for treating recalcitrant P. aeruginosa infections and improving the lives of individuals with CF. Keywords: cystic fibrosis, orphan drugs, Pseudomonas aeruginosa infection

  14. The development of a rubric for peer assessment of individual teamwork skills in undergraduate midwifery students.

    Science.gov (United States)

    Hastie, Carolyn; Fahy, Kathleen; Parratt, Jenny

    2014-09-01

    Poor teamwork is cited as one of the major root causes of adverse events in healthcare. Bullying, resulting in illness for staff, is an expression of poor teamwork skills. Despite this knowledge, poor teamwork persists in healthcare and teamwork skills are rarely the focus of teaching and assessment in undergraduate health courses. To develop and implement an assessment tool for use in facilitating midwifery students' learning of teamwork skills. This paper describes how the TeamUP rubric tool was developed. A review of the literature found no research reports on how to teach and assess health students' teamwork skills in standing teams. The literature, however, gives guidance about how university educators should evaluate individual students using peer assessment. The developmental processes of the rubric were grounded in the theoretical literature and feminist collaborative conversations. The rubric incorporates five domains of teamwork skills: Fostering a Team Climate; Project Planning; Facilitating Teams; Managing Conflict and Quality Individual Contribution. The process and outcomes of student and academic content validation are described. The TeamUP rubric is useful for articulating, teaching and assessing teamwork skills for health professional students. The TeamUP rubric is a robust, theoretically grounded model that defines and details effective teamwork skills and related behaviours. If these skills are mastered, we predict that graduates will be more effective in teams. Our assumption is that graduates, empowered by having these skills, are more likely to manage conflict effectively and less likely to engage in bullying behaviours. Crown Copyright © 2014. Published by Elsevier Ltd. All rights reserved.

  15. And if we forget the talent detection… And if we individualize the development of his Talent

    Directory of Open Access Journals (Sweden)

    Alberto LORENZO

    2015-10-01

    Full Text Available For many years, it has been understood that the process of sport talent identification as a close to magic process (although it is understood in many cases as well, in which the coach was able, by some tests and test batteries, able to predict the future of athletes, and discern among them, who are the graceful people that would be World Champions. What ideas and arguments can lead to think that this is possible? Similarly, under the idea of talent development, it is also thought that, knowing how these athletes who have achieved the highest possible performance, it would also be possible to design a perfect process that allowed younger, if they met perfectly with the path set, reach or even exceed that performance. Do we really think this is possible?Far from accepting such ideas (and that support mainly, we must consider that there are many people who have the potential to produce high yields, in our case in sports. And far from thinking that you are just a graceful by grace of fate or the genetic lottery, we must understand that if we are able to monitor and facilitate the development process of a person, will be closer to being able to achieve the desired levels of performance. What is it that allows or causes an athlete to achieve the expected results when others do not? What factors favor the development of the athlete? How to design the development process of the athlete? We aim in this article summarize the main ideas and arguments with which the detection process and developing talent is addressed, and give the reader some ideas to help improve the learning process of any athlete who may fall into their hands.

  16. 'It's one of the hardest jobs in the world': the experience and understanding of qualified nurses who work with individuals diagnosed with both learning disability and personality disorder.

    Science.gov (United States)

    Lee, Amy; Kiemle, Gundi

    2015-05-01

    This study examines the experiences of qualified nurses working with individuals diagnosed with both intellectual disability and personality disorder (PD) in a medium-secure forensic intellectual disability setting. Potential training needs are highlighted, as well as other ways in which services could better support staff to work effectively with this client group. In-depth, semi-structured interviews were used to explore the nine participants' experiences; the narratives were analysed with interpretative phenomenological analysis (IPA). Four master themes emerged from (i) disorder overriding disability; (ii) resilience; (iii) ambivalence towards label and (iv) knowledge. The findings highlight that for these participants, the clients' intellectual disability appeared to be lost under the complexity of the PD diagnosis. The clinical implications are discussed in terms of developing training, supervision and support. © 2014 John Wiley & Sons Ltd.

  17. Develop a quantitative understanding of rockmass behaviour near excavations in deep mines, part 1

    CSIR Research Space (South Africa)

    Napier, JAL

    1995-12-01

    Full Text Available Control of the rock mass deformation near deep level stopes and the avoidance of damaging incidents of violent rock failure require a fundamental understanding of rock failure mechanisms. Research work to gain this understanding has been undertaken...

  18. Characterization of Atomoxetine Biotransformation and Implications for Development of PBPK Models for Dose Individualization in Children

    Science.gov (United States)

    Pearce, Robin E.; Van Haandel, Leon; Gaedigk, Andrea; Leeder, J. Steven

    2016-01-01

    Atomoxetine (ATX) is a second-line nonstimulant medication used to control symptoms of attention deficit hyperactivity disorder (ADHD). Inconsistent therapeutic efficacy has been reported with ATX, which may be related to variable CYP2D6-mediated drug clearance. We characterized ATX metabolism in a panel of human liver samples as a basis for a bottom-up PBPK model to aid in ATX exposure prediction and control. Km, Vmax, and Clint values in pooled human liver microsomes (HLMs) were 2.4 µM, 479 pmol/min/mg protein, and 202 µl/min/mg protein, respectively. Mean population values of kinetic parameters are not adequate to describe variability in a population, given that Km, Vmax, and Clint values from single-donor HLMs ranged from 0.93 to 79.2 µM, 20.0 to 1600 pmol/min/mg protein, and 0.3 to 936 µl/min/mg protein. All kinetic parameters were calculated from 4-hydroxyatomoxetine (4-OH-ATX) formation. CYP2E1 and CYP3A contributed to 4-OH-ATX formation in livers with CYP2D6 intermediate and poor metabolizer status. In HLMs with lower CYP2D6 activity levels, 2-hydroxymethylatomoxetine (2-CH2OH-ATX) formation became a more predominant pathway of metabolism, which appeared to be catalyzed by CYP2B6. ATX biotransformation at clinically relevant plasma concentrations was characterized in a panel of pediatric HLM (n = 116) samples by evaluating primary metabolites. Competing pathways of ATX metabolism [N-desmethylatomoxetine (NDM-ATX) and 2-CH2OH-ATX formation] had increasing importance in livers with lesser CYP2D6 activity, but, overall ATX clearance was still compromised. Modeling ATX exposure to individualize therapy would require comprehensive knowledge of factors that affect CYP2D6 activity as well as an understanding of competing pathways, particularly for individuals with lower CYP2D6 activity. PMID:27052878

  19. Harnessing Reddit to Understand the Written-Communication Challenges Experienced by Individuals With Mental Health Disorders: Analysis of Texts From Mental Health Communities.

    Science.gov (United States)

    Park, Albert; Conway, Mike

    2018-04-10

    online health communities. Our results also suggest that participating in these platforms has the potential to improve members' written communication. For example, members of all three mental health communities showed statistically significant improvement in both lexical diversity and readability compared with members of the OHC focusing on positive emotion. We provide new insights into the written communication challenges faced by individuals suffering from depression, bipolar disorder, and schizophrenia. A comparison with three other online health communities suggests that written communication in mental health communities is significantly more difficult to read, while also consisting of a significantly less diverse lexicon. We contribute practical suggestions for utilizing our findings in Web-based communication settings to enhance members' communicative experience. We consider these findings to be an important step toward understanding and addressing everyday written communication challenges among individuals suffering from mental disorders. ©Albert Park, Mike Conway. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 10.04.2018.

  20. Understanding the distinct experience of rural interprofessional collaboration in developing palliative care programs.

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    Gaudet, A; Kelley, M L; Williams, A M

    2014-01-01

    Palliative care is one component of rural generalist practice that requires interprofessional collaboration (IPC) amongst practitioners. Previous research on developing rural palliative care has created a four-phase capacity development model that included interprofessional rural palliative care teams; however, the details of rural team dynamics had not been previously explored and defined. A growing body of literature has produced models for interprofessional collaborative practice and identified core competencies required by professionals to work within these contexts. An Ontario College of Family Physicians discussion paper identifies seven essential elements for successful IPC: responsibility and accountability, coordination, communication, cooperation, assertiveness, autonomy, and mutual trust and respect. Despite the fact that IPC may be well conceptualized in the literature, evidence to support the transferability of these elements into rural health care practice or rural palliative care practice is lacking. The purpose of this research is to bridge the knowledge gap that exists with respect to rural IPC, particularly in the context of developing rural palliative care. It examines the working operations of these teams and highlights the elements that are important to rural collaborative processes. For the purpose of this qualitative study, naturalistic and ethnographic research strategies were employed to understand the experience of rural IPC in the context of rural palliative care team development. Purposive sampling was used to recruit key informants as participants who were members of rural palliative care teams. The seven elements of interprofessional collaboration, as outline above, provided a preliminary analytic framework to begin exploring the data. Analysis progressed using a process of interpretive description to embrace new ideas and conceptualizations that emerged from the patterns and themes of the rural health providers' narratives. The

  1. Elementary pre-service teachers' conceptual understanding of dissolving: a Vygotskian concept development perspective

    Science.gov (United States)

    Harrell, Pamela; Subramaniam, Karthigeyan

    2015-09-01

    Background and purpose: The purpose of this study was to investigate and identify the nature and the interrelatedness of pre-service teachers' misconceptions and scientific concepts for explaining dissolving before, during, and after a 5E learning cycle lesson on dissolving, the intervention. Sample, design, and methods: Guided by Vygotsky's theory of concept development, the study focused specifically on the spontaneous, and spontaneous pseudo-concepts held by the 61 elementary pre-service teachers during a 15-week science methods course. Data included concept maps, interview transcripts, written artifacts, drawings, and narratives, and were thematically analyzed to classify concepts and interrelatedness. Results: Results of the study showed that spontaneous pseudo-concepts (1) dominated pre-service teachers' understandings about dissolving throughout the study, and (2) were simply associated with scientific concepts during and after the intervention. Conclusion: Collectively, the results indicated that the pre-service teachers' did not acquire a unified system of knowledge about dissolving that could be characterized as abstract, generalizable, and hierarchical. Implications include the need for (1) familiarity with pre-service teachers' prior knowledge about science content; (2) a variety of formative assessments to assess their misconceptions; (3) emphasizing the importance of dialectical method for concept development during instruction; and (4) skillful content instructors.

  2. Pharmaceutical quality by design: product and process development, understanding, and control.

    Science.gov (United States)

    Yu, Lawrence X

    2008-04-01

    The purpose of this paper is to discuss the pharmaceutical Quality by Design (QbD) and describe how it can be used to ensure pharmaceutical quality. The QbD was described and some of its elements identified. Process parameters and quality attributes were identified for each unit operation during manufacture of solid oral dosage forms. The use of QbD was contrasted with the evaluation of product quality by testing alone. The QbD is a systemic approach to pharmaceutical development. It means designing and developing formulations and manufacturing processes to ensure predefined product quality. Some of the QbD elements include: Defining target product quality profile; Designing product and manufacturing processes; Identifying critical quality attributes, process parameters, and sources of variability; Controlling manufacturing processes to produce consistent quality over time. Using QbD, pharmaceutical quality is assured by understanding and controlling formulation and manufacturing variables. Product testing confirms the product quality. Implementation of QbD will enable transformation of the chemistry, manufacturing, and controls (CMC) review of abbreviated new drug applications (ANDAs) into a science-based pharmaceutical quality assessment.

  3. Recent Developments in Understanding Brain Aging: Implications for Alzheimer's Disease and Vascular Cognitive Impairment.

    Science.gov (United States)

    Deak, Ferenc; Freeman, Willard M; Ungvari, Zoltan; Csiszar, Anna; Sonntag, William E

    2016-01-01

    As the population of the Western world is aging, there is increasing awareness of age-related impairments in cognitive function and a rising interest in finding novel approaches to preserve cerebral health. A special collection of articles in The Journals of Gerontology: Biological Sciences and Medical Sciences brings together information of different aspects of brain aging, from latest developments in the field of neurodegenerative disorders to cerebral microvascular mechanisms of cognitive decline. It is emphasized that although the cellular changes that occur within aging neurons have been widely studied, more research is required as new signaling pathways are discovered that can potentially protect cells. New avenues for research targeting cellular senescence, epigenetics, and endocrine mechanisms of brain aging are also discussed. Based on the current literature it is clear that understanding brain aging and reducing risk for neurological disease with age requires searching for mechanisms and treatment options beyond the age-related changes in neuronal function. Thus, comprehensive approaches need to be developed that address the multiple, interrelated mechanisms of brain aging. Attention is brought to the importance of maintenance of cerebromicrovascular health, restoring neuroendocrine balance, and the pressing need for funding more innovative research into the interactions of neuronal, neuroendocrine, inflammatory and microvascular mechanisms of cognitive impairment, and Alzheimer's disease. © The Author 2015. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  4. Recent Developments in Understanding Brain Aging: Implications for Alzheimer’s Disease and Vascular Cognitive Impairment

    Science.gov (United States)

    Deak, Ferenc; Freeman, Willard M.; Ungvari, Zoltan; Csiszar, Anna

    2016-01-01

    As the population of the Western world is aging, there is increasing awareness of age-related impairments in cognitive function and a rising interest in finding novel approaches to preserve cerebral health. A special collection of articles in The Journals of Gerontology: Biological Sciences and Medical Sciences brings together information of different aspects of brain aging, from latest developments in the field of neurodegenerative disorders to cerebral microvascular mechanisms of cognitive decline. It is emphasized that although the cellular changes that occur within aging neurons have been widely studied, more research is required as new signaling pathways are discovered that can potentially protect cells. New avenues for research targeting cellular senescence, epigenetics, and endocrine mechanisms of brain aging are also discussed. Based on the current literature it is clear that understanding brain aging and reducing risk for neurological disease with age requires searching for mechanisms and treatment options beyond the age-related changes in neuronal function. Thus, comprehensive approaches need to be developed that address the multiple, interrelated mechanisms of brain aging. Attention is brought to the importance of maintenance of cerebromicrovascular health, restoring neuroendocrine balance, and the pressing need for funding more innovative research into the interactions of neuronal, neuroendocrine, inflammatory and microvascular mechanisms of cognitive impairment, and Alzheimer’s disease. PMID:26590911

  5. Towards an understanding of the role of the environment in the development of early callous behavior

    Science.gov (United States)

    Waller, Rebecca; Shaw, Daniel S.; Neiderhiser, Jenae M.; Ganiban, Jody M.; Natsuaki, Misaki N.; Reiss, David; Trentacosta, Christopher; Leve, Leslie D.; Hyde, Luke W.

    2015-01-01

    Key to understanding the long-term impact of social inequalities is identifying early behaviors that may signal higher risk for later poor psychosocial outcomes, such as psychopathology. A set of early-emerging characteristics that may signal risk for later externalizing psychopathology is Callous-Unemotional (CU) behavior. CU behavior predict severe and chronic trajectories of externalizing behaviors in youth. However, much research on CU behavior has focused on late childhood and adolescence, with little attention paid to early childhood when preventative interventions may be most effective. In this paper, we summarize our recent work showing that: (1) CU behavior can be identified in early childhood using items from common behavior checklists; (2) CU behavior predicts worse outcomes across early childhood; (3) CU behavior exhibits a distinct nomological network from other early externalizing behaviors; and (4) malleable environmental factors, particularly parenting, may play a role in the development of early CU behaviors. We discuss the challenges of studying contextual contributors to the development of CU behavior in terms of gene-environment correlations and present initial results from work examining CU behavior in an adoption study in which gene-environment correlations are examined in early childhood. We find that parenting is a predictor of early CU behavior even in a sample in which parents are not genetically related to the children. PMID:26291075

  6. Understanding the direct involvement of parents in policy development and school activities in a primary school

    Directory of Open Access Journals (Sweden)

    Tobin Bernie

    2017-12-01

    Full Text Available It is acknowledged that parental engagement with children’s learning and education is of vital importance. But, there is a tendency to confuse engagement with learning with engagement with the school. While all types of parents’ involvement can have a positive effect, it is actually what parents do with their child at home that has the greatest impact. However, unless parental involvement in learning is embedded in whole-school processes it is unlikely to as effective as possible. This paper documents an action research study that explores the inclusion of parents and home values in the construction of the teaching and learning environment. This was a small step towards positive parent-teacher collaboration, which allowed an exchange of knowledge, values and cultural background experiences. In acknowledging the ways in which the parents already engaged with their children’s learning, it began to enhance self-efficacy in their ability to directly affect this learning. This work has also provoked reflexive engagement of my influence and understanding of involving parents of children with additional and diverse learning needs. But, it also details the transformative journey that influenced my thinking about how we as a school could begin to develop whole-school processes to directly involve parents in policy development and school activities.

  7. Understanding the gastrointestinal tract of the elderly to develop dietary solutions that prevent malnutrition

    Science.gov (United States)

    Rémond, Didier; Shahar, Danit R.; Gille, Doreen; Pinto, Paula; Kachal, Josefa; Peyron, Marie-Agnès; Dos Santos, Claudia Nunes; Walther, Barbara; Bordoni, Alessandra; Dupont, Didier; Tomás-Cobos, Lidia; Vergères, Guy

    2015-01-01

    Although the prevalence of malnutrition in the old age is increasing worldwide a synthetic understanding of the impact of aging on the intake, digestion, and absorption of nutrients is still lacking. This review article aims at filling the gap in knowledge between the functional decline of the aging gastrointestinal tract (GIT) and the consequences of malnutrition on the health status of elderly. Changes in the aging GIT include the mechanical disintegration of food, gastrointestinal motor function, food transit, chemical food digestion, and functionality of the intestinal wall. These alterations progressively decrease the ability of the GIT to provide the aging organism with adequate levels of nutrients, what contributes to the development of malnutrition. Malnutrition, in turn, increases the risks for the development of a range of pathologies associated with most organ systems, in particular the nervous-, muscoskeletal-, cardiovascular-, immune-, and skin systems. In addition to psychological, economics, and societal factors, dietary solutions preventing malnutrition should thus propose dietary guidelines and food products that integrate knowledge on the functionality of the aging GIT and the nutritional status of the elderly. Achieving this goal will request the identification, validation, and correlative analysis of biomarkers of food intake, nutrient bioavailability, and malnutrition. PMID:26091351

  8. Patient understanding of the revised USPSTF screening mammogram guidelines: need for development of patient decision aids

    Directory of Open Access Journals (Sweden)

    Allen Summer V

    2012-10-01

    Full Text Available Abstract Background The purpose of the study was to examine patients’ understanding of the revised screening mammogram guidelines released by the United States Preventive Services Task Force (USPSTF in 2009 addressing age at initiation and frequency of screening mammography. Methods Patients from the Departments of Family Medicine, Internal Medicine, and Obstetrics and Gynecology (n = 150 at a tertiary care medical center in the United States completed a survey regarding their understanding of the revised USPSTF guidelines following their release, within four to six months of their scheduled mammogram (March 2010 to May 2010. Results Of the patients surveyed, 97/147 (67% indicated increased confusion regarding the age and frequency of screening mammography, 61/148 (41% reported increased anxiety about mammograms, and 58/146 (40% reported anxiety about their own health status following the release of the revised screening guidelines. Most of the patients surveyed, 111/148 (75%, did not expect to change their timing or frequency of screening mammograms in the future. Conclusion Results from this survey suggested increased confusion and possibly an increase in patients’ anxiety related to screening mammography and their own health status following the release of the revised USPSTF screening mammogram guidelines to the public and subsequent media portrayal of the revised guidelines. Although the study did not specifically address causality for these findings, the results highlight the need for improvements in the communication of guidelines to patients and the public. Development of shared decision-making tools and outcomes should be considered to address the communication challenge.

  9. The Lay Public’s Understanding and Perception of Dementia in a Developed Asian Nation

    Directory of Open Access Journals (Sweden)

    Wai Jia Tan

    2012-10-01

    Full Text Available Background: Early detection of dementia aims to improve treatment outcomes. However, poor perception and understanding of dementia are significant barriers. We aim to investigate the public’s perception of dementia and identify variables associated with the different profiles of public perception. Methods: A custom-designed questionnaire was used to assess laypersons’ knowledge and perception of dementia during a health fair at a public hospital in Singapore, a developed Asian nation. Out of a sample of 370 subjects, 32 declined to participate (response rate = 91.4%. Latent class analysis (LCA was used to identify meaningful subgroups of subjects from significant associations with multiple indicators of dementia awareness. Multinomial logistic regression was performed exploring variables associated with each of the subgroups derived from LCA. Results: The majority of the study participants were female (66.9%, 65 years or older (71.1%, and ethnic Chinese (88.1%. LCA classified the study participants into 3 subgroups: Class 1 (good knowledge, good attitude, Class 2 (good knowledge, poor attitude, and Class 3 (poor knowledge, poor attitude, in proportions of 14.28, 63.83, and 21.88%, respectively. Compared to other classes, participants with good knowledge and good attitude towards dementia (Class 1 were more likely to know someone with dementia and understand the effects of the disease, be married, live in private housing, receive higher monthly income, and not profess belief in Buddhism, Taoism, or Hinduism. Conclusion: Our results show that the public in Singapore may not be ready for screening initiatives and early dementia diagnosis. Education efforts should be targeted at lower socioeconomic groups, singles, and those of certain oriental religions.

  10. The numeracy understanding in medicine instrument: a measure of health numeracy developed using item response theory.

    Science.gov (United States)

    Schapira, Marilyn M; Walker, Cindy M; Cappaert, Kevin J; Ganschow, Pamela S; Fletcher, Kathlyn E; McGinley, Emily L; Del Pozo, Sam; Schauer, Carrie; Tarima, Sergey; Jacobs, Elizabeth A

    2012-01-01

    Health numeracy can be defined as the ability to understand and apply information conveyed with numbers, tables and graphs, probabilities, and statistics to effectively communicate with health care providers, take care of one's health, and participate in medical decisions. To develop the Numeracy Understanding in Medicine Instrument (NUMi) using item response theory scaling methods. A 20-item test was formed drawing from an item bank of numeracy questions. Items were calibrated using responses from 1000 participants and a 2-parameter item response theory model. Construct validity was assessed by comparing scores on the NUMi to established measures of print and numeric health literacy, mathematic achievement, and cognitive aptitude. Community and clinical populations in the Milwaukee and Chicago metropolitan areas. Twenty-nine percent of the 1000 respondents were Hispanic, 24% were non-Hispanic white, and 42% were non-Hispanic black. Forty-one percent had no more than a high school education. The mean score on the NUMi was 13.2 (s = 4.6) with a Cronbach α of 0.86. Difficulty and discrimination item response theory parameters of the 20 items ranged from -1.70 to 1.45 and 0.39 to 1.98, respectively. Performance on the NUMi was strongly correlated with the Wide Range Achievement Test-Arithmetic (0.73, P < 0.001), the Lipkus Expanded Numeracy Scale (0.69, P < 0.001), the Medical Data Interpretation Test (0.75, P < 0.001), and the Wonderlic Cognitive Ability Test (0.82, P < 0.001). Performance was moderately correlated to the Short Test of Functional Health Literacy (0.43, P < 0.001). The NUMi was found to be most discriminating among respondents with a lower-than-average level of health numeracy. The NUMi can be applied in research and clinical settings as a robust measure of the health numeracy construct.

  11. Instructional games: Scientific language use, concept understanding, and attitudinal development of middle school learners

    Science.gov (United States)

    Mongillo, Geraldine

    The purpose of this qualitative study was to discover the influence of instructional games on middle school learners' use of scientific language, concept understanding, and attitude toward learning science. The rationale for this study stemmed from the lack of research concerning the value of play as an instructional strategy for older learners. Specifically, the study focused on the ways in which 6 average ability 7th grade students demonstrated scientific language and concept use during gameplay. The data were collected for this 6-week study in a southern New Jersey suburban middle school and included audio recordings of the 5 games observed in class, written documents (e.g., student created game questions, self-evaluation forms, pre- and post-assessments, and the final quiz) interviews, and researcher field notes. Data were coded and interpreted borrowing from the framework for scientific literacy developed by Bybee (1997). Based on the findings, the framework was modified to reflect the level of scientific understanding demonstrated by the participants and categorized as: Unacquainted, Nominal, Functional, and Conceptual. Major findings suggested that the participants predominantly achieved the Functional level of scientific literacy (i.e., the ability to adequately and appropriately use scientific language in both written and oral discourse) during games. Further, it was discovered that the participants achieved the Conceptual level of scientific literacy during gameplay. Through games participants were afforded the opportunity to use common, everyday language to explore concepts, promoted through peer collaboration. In games the participants used common language to build understandings that exceeded Nominal or token use of the technical vocabulary and concepts. Additionally, the participants reported through interviews and self-evaluation forms that their attitude (patterns included: Motivation, Interest, Fun, Relief from Boredom, and an Alternate Learning

  12. Direct Aggression and Generalized Anxiety in Adolescence: Heterogeneity in Development and Intra-Individual Change.

    Science.gov (United States)

    Meeus, Wim; Van de Schoot, Rens; Hawk, Skyler T; Hale, William W; Branje, Susan

    2016-02-01

    Co-occurrence of aggression and anxiety might change during adolescence, or stay stable. We studied change and stability of four types of co-occurrence regarding direct aggression and anxiety in adolescence: an anxious and non-aggressive type, an aggressive and non-anxious type, a comorbid aggressive-anxious type and a no problems type. We applied a person-centered approach to assess increases and decreases of these types, and tested various models of intra-individual change of the types: the stability, acting out and failure models. We used data from a five-wave study of 923 early-to-middle and 390 middle-to-late adolescents (48.5 % male), thereby covering the ages of 12-20. We observed accelerated development in the older cohort: adolescents tended to grow faster out of the aggressive types in middle-to-late adolescence than in early-to-middle adolescence. We observed one other group-dependent pattern of heterogeneity in development, namely "gender differentiation": gender differences in aggression and generalized anxiety became stronger over time. We found support for two perspectives on intra-individual change of the four types, namely the stability and the acting out perspective. The no problems--and to a lesser extent the anxious--type proved to be stable across time. Acting out was found in early-to-middle adolescents, males, and adolescents with poorer-quality friendships. In all three groups, there were substantial transitions from the anxious type to the aggressive type during 4 years (between 20 and 41 %). Remarkably, acting out was most prevalent in subgroups that, generally speaking, are more vulnerable for aggressive behavior, namely early-to-middle adolescents and males. We interpret acting out as the attempt of adolescents to switch from anxiety to instrumental aggression, in order to become more visible and obtain an autonomous position in the adolescent world. Acting out contributed to the explanation of accelerated development and gender

  13. Developing of Individual Instrument Performance Anxiety Scale: ValidityReliability Study

    Directory of Open Access Journals (Sweden)

    Esra DALKIRAN

    2016-07-01

    Full Text Available In this study, it is intended to develop a scale unique to our culture, concerning individual instrument performance anxiety of the students who are getting instrument training in the Department of Music Education. In the study, the descriptive research model is used and qualitative research techniques are utilized. The study population consists of the students attending the 23 universities which has Music Education Department. The sample of the study consists of 438 girls and 312 boys, totally 750 students who are studying in the Department of Music Education of randomly selected 10 universities. As a result of the explanatory and confirmatory factor analyses that were performed, a onedimensional structure consisting of 14 items was obtained. Also, t-scores and the coefficient scores of total item correlation concerning the distinguishing power of the items, the difference in the scores of the set of lower and upper 27% was calculated, and it was observed that the items are distinguishing as a result of both analyses. Of the scale, Cronbach's alpha coefficient of internal consistency was calculated as .94, and test-retest reliability coefficient was calculated as .93. As a result, a valid and reliable assessment and evaluation instrument that measures the exam performance anxiety of the students studying in the Department of Music Education, has been developed.

  14. Mentoring to develop research selfefficacy, with particular reference to previously disadvantaged individuals

    Directory of Open Access Journals (Sweden)

    S. Schulze

    2010-07-01

    Full Text Available The development of inexperienced researchers is crucial. In response to the lack of research self-efficacy of many previously disadvantaged individuals, the article examines how mentoring can enhance the research self-efficacy of mentees. The study is grounded in the self-efficacy theory (SET – an aspect of the social cognitive theory (SCT. Insights were gained from an in-depth study of SCT, SET and mentoring, and from a completed mentoring project. This led to the formulation of three basic principles. Firstly, institutions need to provide supportive environmental conditions that facilitate research selfefficacy. This implies a supportive and efficient collective system. The possible effects of performance ratings and reward systems at the institution also need to be considered. Secondly, mentoring needs to create opportunities for young researchers to experience successful learning as a result of appropriate action. To this end, mentees need to be involved in actual research projects in small groups. At the same time the mentor needs to facilitate skills development by coaching and encouragement. Thirdly, mentors need to encourage mentees to believe in their ability to successfully complete research projects. This implies encouraging positive emotional states, stimulating self-reflection and self-comparison with others in the group, giving positive evaluative feedback and being an intentional role model.

  15. The Impact of International Tourism on the Economic Development and the Image of an Individual Country

    Directory of Open Access Journals (Sweden)

    Yevtushenko Viktoriia А.

    2017-06-01

    Full Text Available The aim of the paper is to study the dynamics of economic indicators of international tourism, the main problems, trends and prospects of the industry development in the world market and an individual country, the role of the country’s image and its impact of on the creation of a competitive tourist product. There considered the dynamics of statistical indicators of the international tourism structure, in particular the tourist flow, contribution to the world GDP and employment, and national economies. The analysis of the status of the tourist industry of Ukraine in the context of the main economic indicators and hotel infrastructure is conducted using the example of Kharkov region. The role of the image and its influence on the competitiveness of the national tourist product is revealed. On the basis of correlation analysis, forecast models for a number of indicators are created. The present trends in the development of the tourist industry of Ukraine are identified and recommendations on improving its competitiveness are given.

  16. Factors to consider in developing individual pharmaceutical product quality risk profiles useful to government procurement agencies.

    Science.gov (United States)

    Xu, Wei; Boehm, Garth; Zheng, Qiang

    2016-01-01

    Governments that procure pharmaceutical products from an Essential Medicine List (EML) bear special responsibility for the quality of these products. In this article we examine the possibility of developing a pharmaceutical product quality risk assessment scheme for use by government procurement officials. We use the Chinese EML as a basis, and US recall data is examined as it is publically available.This is justified as the article is only concerned with inherent product quality risks. After establishing a link between Chinese essential medicines and those available in the US, we examine US recall data to separate product specific recalls. We conclude that, in addition to existing manufacturing based risks, there are two other product specific risks that stand out from all others, degradation and dissolution failure. Methodology for relative product risk for degradation is needed to be developed and further work is required to better understand dissolution failures which largely occur with modified-release solid oral products. We conclude that a product specific quality risk profile would be enhanced by including a risk assessment for degradation for all products, and in the case of solid oral products, dissolution.

  17. Experimental and Modeling Approaches for Understanding the Effect of Gene Expression Noise in Biological Development

    Directory of Open Access Journals (Sweden)

    David M. Holloway

    2018-04-01

    Full Text Available Biological development involves numerous chemical and physical processes which must act in concert to reliably produce a cell, a tissue, or a body. To be successful, the developing organism must be robust to variability at many levels, such as the environment (e.g., temperature, moisture, upstream information (such as long-range positional information gradients, or intrinsic noise due to the stochastic nature of low concentration chemical kinetics. The latter is especially relevant to the regulation of gene expression in cell differentiation. The temporal stochasticity of gene expression has been studied in single celled organisms for nearly two decades, but only recently have techniques become available to gather temporally-resolved data across spatially-distributed gene expression patterns in developing multicellular organisms. These demonstrate temporal noisy “bursting” in the number of gene transcripts per cell, raising the question of how the transcript number defining a particular cell type is produced, such that one cell type can reliably be distinguished from a neighboring cell of different type along a tissue boundary. Stochastic spatio-temporal modeling of tissue-wide expression patterns can identify signatures for specific types of gene regulation, which can be used to extract regulatory mechanism information from experimental time series. This Perspective focuses on using this type of approach to study gene expression noise during the anterior-posterior segmentation of the fruit fly embryo. Advances in experimental and theoretical techniques will lead to an increasing quantification of expression noise that can be used to understand how regulatory mechanisms contribute to embryonic robustness across a range of developmental processes.

  18. Applying Personality Type Theory to Develop Individualized Wellness Plans for Reducing Chronic Diseases

    Directory of Open Access Journals (Sweden)

    Jon C. Schommer

    2017-01-01

    Full Text Available Objective: The objective of this study was to explore if characteristics of personality type (using the Preferred Communication Style Questionnaire are associated with activities people prefer for getting adequate exercise, losing weight, managing stress, quitting smoking, reducing alcohol consumption, and taking medications as prescribed. Methods: The data source for this study was the 2016 National Consumer Survey of the Medication Experience and Pharmacists’ Roles. Data were collected via an on-line, self-administered survey conducted from March 14-30, 2016. Data were obtained from 10,500 adults residing in the United States. Chi-square analysis was used for making comparisons between categories of personality types and how respondents believed they could best reach their personal goals. Statistical significance was set at p < 0.05. Practical significance was set at five or more percentage points above or below the overall mean. Results: Findings showed that (1 there are key differences between individuals that impact their behavior and (2 these differences can be easily and accurately identified using the Preferred Communication Style Questionnaire. The findings supported the notion that individuals are more likely to experience success in changing health-risk behaviors if they engage in activities that are consistent with (i how they are energized, (ii the kind of information they naturally notice, (iii how they prefer to make decisions, and (iv their preferences to live in a more structured way or in a more spontaneous way. Conclusions: Personality type characteristics can be used to develop and implement successful change strategies and intervention tools, such as individualized wellness plans (IWPTM that help promote intention stability, create implementation intention, resist situational pressure, reduce the impact of past habits on future performances, and improve change maintenance. Conflict of Interest We declare no conflicts of

  19. Developing and validating the Communication Function Classification System for individuals with cerebral palsy

    Science.gov (United States)

    HIDECKER, MARY JO COOLEY; PANETH, NIGEL; ROSENBAUM, PETER L; KENT, RAYMOND D; LILLIE, JANET; EULENBERG, JOHN B; CHESTER, KEN; JOHNSON, BRENDA; MICHALSEN, LAUREN; EVATT, MORGAN; TAYLOR, KARA

    2011-01-01

    Aim The purpose of this study was to create and validate a Communication Function Classification System (CFCS) for children with cerebral palsy (CP) that can be used by a wide variety of individuals who are interested in CP. This paper reports the content validity, interrater reliability, and test–retest reliability of the CFCS for children with CP. Method An 11-member development team created comprehensive descriptions of the CFCS levels, and four nominal groups comprising 27 participants critiqued these levels. Within a Delphi survey, 112 participants commented on the clarity and usefulness of the CFCS. Interrater reliability was completed by 61 professionals and 68 parents/relatives who classified 69 children with CP aged 2 to 18 years. Test–retest reliability was completed by 48 professionals who allowed at least 2 weeks between classifications. The participants who assessed the CFCS were all relevant stakeholders: adults with CP, parents of children with CP, educators, occupational therapists, physical therapists, physicians, and speech–language pathologists. Results The interrater reliability of the CFCS was 0.66 between two professionals and 0.49 between a parent and a professional. Professional interrater reliability improved to 0.77 for classification of children older than 4 years. The test–retest reliability was 0.82. Interpretation The CFCS demonstrates content validity and shows very good test–retest reliability, good professional interrater reliability, and moderate parent–professional interrater reliability. Combining the CFCS with the Gross Motor Function Classification System and the Manual Ability Classification System contributes to a functional performance view of daily life for individuals with CP, in accordance with the World Health Organization’s International Classification of Functioning, Disability and Health. PMID:21707596

  20. Development of sustained and dual drug release co-extrusion formulations for individual dosing.

    Science.gov (United States)

    Laukamp, Eva Julia; Vynckier, An-Katrien; Voorspoels, Jody; Thommes, Markus; Breitkreutz, Joerg

    2015-01-01

    In personalized medicine and patient-centered medical treatment individual dosing of medicines is crucial. The Solid Dosage Pen (SDP) allows for an individual dosing of solid drug carriers by cutting them into tablet-like slices. The aim of the present study was the development of sustained release and dual release formulations with carbamazepine (CBZ) via hot-melt co-extrusion for the use in the SDP. The selection of appropriate coat- and core-formulations was performed by adapting the mechanical properties (like tensile strength and E-modulus) for example. By using different excipients (polyethyleneglycols, poloxamers, white wax, stearic acid, and carnauba wax) and drug loadings (30-50%) tailored dissolution kinetics was achieved showing cube root or zero order release mechanisms. Besides a biphasic drug release, the dose-dependent dissolution characteristics of sustained release formulations were minimized by a co-extruded wax-coated formulation. The dissolution profiles of the co-extrudates were confirmed during short term stability study (six months at 21.0 ± 0.2 °C, 45%r.h.). Due to a good layer adhesion of core and coat and adequate mechanical properties (maximum cutting force of 35.8 ± 2.0 N and 26.4 ± 2.8 N and E-modulus of 118.1 ± 8.4 and 33.9 ± 4.5 MPa for the dual drug release and the wax-coated co-extrudates, respectively) cutting off doses via the SDP was precise. While differences of the process parameters (like the barrel temperature) between the core- and the coat-layer resulted in unsatisfying content uniformities for the wax-coated co-extrudates, the content uniformity of the dual drug release co-extrudates was found to be in compliance with pharmacopoeial specification. Copyright © 2015 Elsevier B.V. All rights reserved.

  1. Understanding balance differences in individuals with multiple sclerosis with mild disability: An investigation of differences in sensory feedback on postural and dynamic balance control

    Science.gov (United States)

    Denomme, Luke T.

    Multiple sclerosis (MS) is an autoimmune disease that affects the central nervous system (CNS) and causes a broad range of neurological symptoms. One of the most common symptoms experienced by individuals with MS is poor balance control during standing and walking. The main mechanism underlying impaired balance control in MS appears to result from slowed somatosensory conduction and impaired central integration. The current thesis assessed postural and dynamic control of balance of 'individuals with MS with mild disability' (IwMS). IwMS were compared to 'healthy age-matched individuals' (HAMI) and community-dwelling 'older adults' (OA). The purpose of this thesis was to quantify differences in postural and dynamic control of balance in IwMS to the two populations who display balance control differences across the lifespan and represent two extreme ends of the balance control continuum due to natural aging. IwMS (n = 12, x¯age: 44 +/- 9.4 years), HAMI (n = 12, x¯age: 45 +/- 9.9 years) and community-dwelling OA (n = 12, x¯ age: 68.1 +/- 4.5 years) postural and dynamic balance control were evaluated during a Romberg task as well as a dynamic steering task. The Romberg task required participants to stand with their feet together and hands by their sides for 45 seconds with either their eyes open or closed. The dynamic steering task required participants to walk and change direction along the M-L plane towards a visual goal. Results from these two tasks reveal that IwMS display differences in postural control when compared to HAMI when vision was removed as well as differences in dynamic stability margin during steering situations. During the postural control task IwMS displayed faster A-P and M-L COP velocities when vision was removed and their COP position was closer to their self-selected maximum stability limits compared to HAMI. Assessment of dynamic stability during the steering task revealed that IwMS displayed reduced walking speed and cadence during the

  2. Significance of epigenetics for understanding brain development, brain evolution and behaviour.

    Science.gov (United States)

    Keverne, E B

    2014-04-04

    Two major environmental developments have occurred in mammalian evolution which have impacted on the genetic and epigenetic regulation of brain development. The first of these was viviparity and development of the placenta which placed a considerable burden of time and energy investment on the matriline, and which resulted in essential hypothalamic modifications. Maternal feeding, maternal care, parturition, milk letdown and the suspension of fertility and sexual behaviour are all determined by the maternal hypothalamus and have evolved to meet foetal needs under the influence of placental hormones. Viviparity itself provided a new environmental variable for selection pressures to operate via the co-existence over three generations of matrilineal genomes (mother, developing offspring and developing oocytes) in one individual. Also of importance for the matriline has been the evolution of epigenetic marks (imprint control regions) which are heritable and undergo reprogramming primarily in the oocyte to regulate imprinted gene expression according to parent of origin. Imprinting of autosomal genes has played a significant role in mammalian evolutionary development, particularly that of the hypothalamus and placenta. Indeed, many imprinted genes that are co-expressed in the placenta and hypothalamus play an important role in the co-adapted functioning of these organs. Thus the action and interaction of two genomes (maternal and foetal) have provided a template for transgenerational selection pressures to operate in shaping the mothering capabilities of each subsequent generation. The advanced aspects of neocortical brain evolution in primates have emancipated much of behaviour from the determining effects of hormonal action. Thus in large brain primates, most of the sexual behaviour is not reproductive hormone dependent and maternal care can and does occur outside the context of pregnancy and parturition. The neocortex has evolved to be adaptable and while the adapted

  3. Measuring Transgender Individuals' Comfort with Gender Identity and Appearance: Development and Validation of the Transgender Congruence Scale

    Science.gov (United States)

    Kozee, Holly B.; Tylka, Tracy L.; Bauerband, L. Andrew

    2012-01-01

    Our study used the construct of congruence to conceptualize the degree to which transgender individuals feel genuine, authentic, and comfortable with their gender identity and external appearance. In Study 1, the Transgender Congruence scale (TCS) was developed, and data from 162 transgender individuals were used to estimate the reliability and…

  4. Geo-Hazards and Mountain Road Development in Nepal: Understanding the Science-Policy-Governance Interface

    Science.gov (United States)

    Dugar, Sumit; Dahal, Vaskar

    2015-04-01

    The foothills of Nepalese Himalayas located in the neotectonic mountain environment are among some of the most unstable and geomorphologically dynamic landscapes in the world. Young fold mountains in this region are characterized by complex tectonics that influence the occurrence of earthquakes, while climatic processes such as intense orographic rainfall often dictate the occurrence of floods and landslides. Development of linear infrastructures, such as roads, in mountainous terrain characterized by high relief and orogeny is considerably challenging where the complexity of landscape in steep and irregular topography, difficult ground conditions and weak geology, presents engineers and planners with numerous difficulties to construct and maintain mountain roads. Whilst application of engineering geology, geomorphic interpretation of terrain in terms of physiography and hydrology, and identification of geo-hazards along the road corridor is critical for long term operation of mountain roads, low-cost arterial roads in the Himalayan foothills generally fail to incorporate standard road slope engineering structures. This research provides unique insights on policy and governance issues in developing mountainous countries such as Nepal, where achieving a sound balance between sustainability and affordability is a major challenge for road construction. Road development in Nepal is a complex issue where socio-economic and political factors influence the budget allocation for road construction in rural hilly areas. Moreover, most mountain roads are constructed without any geological or geo-technical site investigations due to rampant corruption and lack of adequate engineering supervision. Despite having good examples of rural road construction practices such as the Dharan-Dhankuta Road in Eastern Nepal where comprehensive terrain-evaluation methods and geo-technical surveys led to an improved understanding of road construction, learnings from this project have not

  5. A design study to develop young children's understanding of multiplication and division

    Science.gov (United States)

    Bicknell, Brenda; Young-Loveridge, Jenny; Nguyen, Nhung

    2016-12-01

    This design study investigated the use of multiplication and division problems to help 5-year-old children develop an early understanding of multiplication and division. One teacher and her class of 15 5-year-old children were involved in a collaborative partnership with the researchers. The design study was conducted over two 4-week periods in May-June and October-November. The focus in this article is on three key aspects of classroom teaching: instructional tasks, the use of representations, and discourse, including the mathematics register. Results from selected pre- and post-assessment tasks within a diagnostic interview showed that there were improvements in addition and subtraction as well as multiplication and division, even though the teaching had used multiplication and division problems. Students made progress on all four operational domains, with effect sizes ranging from approximately two thirds of a standard deviation to 2 standard deviations. Most of the improvement in students' number strategies was in moving from `counting all' to `counting on' and `skip counting'. The findings challenge the idea that learning experiences in addition and subtraction should precede those in multiplication and division as suggested in some curriculum documents.

  6. Limits to oil pricing: scenario planning as a device to understand oil price developments

    International Nuclear Information System (INIS)

    Austvik, O.G.

    1992-01-01

    This paper underlines that the politicizing of the oil market makes economics, politics and even pure warfare important elements in the formation of the price of oil. The disagreement about which theory to use to analyze the market and the bad record of oil price forecasting indicates that conventional oil market models should be critically re-assessed. The scenario planning methodology presented in this paper may be one alternative approach. SP does not overthrow any other theories of the market. But it claims that no single discipline is able to tell the whole truth about the market. The SP approach stresses and clarifies the role of uncertainty in the development of oil prices and underlines the importance of the understanding of the functioning of the market. It argues that without a cross-disciplinary approach, with an adequate choice of parameters, at the right level of in-depth discussion, the analysis may lose essential input or drown in detail. As an example of the methodology, an analysis of development of oil prices in the nineties is presented. It is shown that lower (indicated as 15-20 S/bbl) and upper (indicated as 30-40 S/bbl) limits of the price in the long run can be constructed, based on economic, political and strategic reasoning. It is also argued that short run 'shocks' outside these limits may have become less likely, because: (1) the strategic petroleum reserves (SPR) will cut off the most extreme prices above the upper limit and (2) the existence of a supply side regulator, like OPEC, will prevent prices from dropping below the lower limit for any longer period of time. Sensitivity analysis tests the 'robustness' of the approach. 10 refs., 1 fig

  7. Computer Administered Safety Planning for Individuals at Risk for Suicide: Development and Usability Testing.

    Science.gov (United States)

    Boudreaux, Edwin D; Brown, Gregory K; Stanley, Barbara; Sadasivam, Rajani S; Camargo, Carlos A; Miller, Ivan W

    2017-05-15

    Safety planning is a brief intervention that has become an accepted practice in many clinical settings to help prevent suicide. Even though it is quick compared to other approaches, it frequently requires 20 min or more to complete, which can impede adoption. A self-administered, Web-based safety planning application could potentially reduce clinician time, help promote standardization and quality, and provide enhanced ability to share the created plan. The aim of this study was to design, build, and test the usability of a Web-based, self-administered safety planning application. We employed a user-centered software design strategy led by a multidisciplinary team. The application was tested for usability with a target sample of suicidal patients. Detailed observations, structured usability ratings, and Think Aloud procedures were used. Suicidal ideation intensity and perceived ability to cope were assessed pre-post engagement with the Web application. A total of 30 participants were enrolled. Usability ratings were generally strong, and all patients successfully built a safety plan. However, the completeness of the safety plan varied. The mean number of steps completed was 5.5 (SD 0.9) out of 6, with 90% (27/30) of participants completing at least 5 steps and 67% (20/30) completing all 6 steps. Some safety planning steps were viewed as inapplicable to some individuals. Some confusion in instructions led to modifications to improve understandability of each step. Ratings of suicide intensity after completion of the application were significantly lower than preratings, pre: mean 5.11 (SD 2.9) versus post: mean 4.46 (SD 3.0), t 27 =2.49, P=.02. Ratings of ability to cope with suicidal thoughts after completion of the application were higher than preratings, with the difference approaching statistical significance, pre: mean 5.93 (SD 2.9), post: mean 6.64 (SD 2.4), t 27 =-2.03, P=.05. We have taken the first step toward identifying the components needed to maximize

  8. Computer Administered Safety Planning for Individuals at Risk for Suicide: Development and Usability Testing

    Science.gov (United States)

    Brown, Gregory K; Stanley, Barbara; Sadasivam, Rajani S; Camargo, Carlos A; Miller, Ivan W

    2017-01-01

    Background Safety planning is a brief intervention that has become an accepted practice in many clinical settings to help prevent suicide. Even though it is quick compared to other approaches, it frequently requires 20 min or more to complete, which can impede adoption. A self-administered, Web-based safety planning application could potentially reduce clinician time, help promote standardization and quality, and provide enhanced ability to share the created plan. Objective The aim of this study was to design, build, and test the usability of a Web-based, self-administered safety planning application. Methods We employed a user-centered software design strategy led by a multidisciplinary team. The application was tested for usability with a target sample of suicidal patients. Detailed observations, structured usability ratings, and Think Aloud procedures were used. Suicidal ideation intensity and perceived ability to cope were assessed pre-post engagement with the Web application. Results A total of 30 participants were enrolled. Usability ratings were generally strong, and all patients successfully built a safety plan. However, the completeness of the safety plan varied. The mean number of steps completed was 5.5 (SD 0.9) out of 6, with 90% (27/30) of participants completing at least 5 steps and 67% (20/30) completing all 6 steps. Some safety planning steps were viewed as inapplicable to some individuals. Some confusion in instructions led to modifications to improve understandability of each step. Ratings of suicide intensity after completion of the application were significantly lower than preratings, pre: mean 5.11 (SD 2.9) versus post: mean 4.46 (SD 3.0), t27=2.49, P=.02. Ratings of ability to cope with suicidal thoughts after completion of the application were higher than preratings, with the difference approaching statistical significance, pre: mean 5.93 (SD 2.9), post: mean 6.64 (SD 2.4), t27=−2.03, P=.05. Conclusions We have taken the first step toward

  9. Individual demands of human embryos on IVF culture medium: influence on blastocyst development and pregnancy outcome.

    Science.gov (United States)

    Wirleitner, B; Vanderzwalmen, P; Stecher, A; Zech, M H; Zintz, M; Zech, N H

    2010-12-01

    The elucidation of the metabolic requirements of human embryos in vivo or in vitro remains, despite being intensively investigated, a work in progress. The adoption of extended embryo culture to the blastocyst stage during the last decade has entailed new challenges. With the increased attention to culture media formulations, more evidence on the sensitivity of embryos to their early environmental conditions is accumulating which might affect phenotype and developmental potential. A retrospective study was conducted that comprised 286 IVF cycles to evaluate the effect of two different culture media on blastocyst development and pregnancy outcome. Embryos were either cultured in a one step or a sequential medium. Higher fertilization rates and augmented blastocyst rates as well as higher implantation rates were observed when embryos were cultured in one step medium (Pcultured in either medium resulted in a significantly higher rate of twin pregnancies. Although multiple pregnancies should be avoided in assisted reproduction treatment to reduce risks for offspring and mother, this higher frequency of twin pregnancies resulting from the transfer of embryos derived from different culture media suggests that each embryo makes individual demands on its early environment. Copyright © 2010 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

  10. Development of animal welfare understanding drives change in minimum welfare standards.

    Science.gov (United States)

    Mellor, D J; Webster, J R

    2014-04-01

    The process by which societies adapt to increasing knowledge about the mental and physical capacities of animals and the ways in which they are affected by human activities has been described as a journey. Different countries and regions are at various stages of this journey, and will take a unique path, depending on their specific social and cultural dynamics. However, all participants are unified by an increasing awareness of, and concern for, animal welfare. This journey has been characterised by a number of landmark events, one of which was the release of the Five Freedoms concept. Although aspirational and abstract, as it did not outline specific practical goals, nonetheless this concept became a catalyst for moving animal welfare thinking in a new direction, and set up a number of important targets for research. This eventually led to a key shift in thinking from a focus on biological functioning and resources, to ways of assessing welfare outcomes in terms of animals' experiences, i.e. their affective states. Behaviour science played an important role in the interpretation of animals' affective experiences, receiving compelling support from parallel studies in affective neuroscience. An important aspect of our understanding of animal welfare is that affective states can be negative or positive. Enabling animals to perform specific behaviours at key times when they are needed is central to the achievement of positive affective states. Another important event has been the development of practical ways to shift the spectrum of affective states towards a positive balance and their incorporation into welfare codes and regulations. The recent focus on positive affective states does not mean that negative experiences should be given less attention. In fact, in those countries that are at the early stages of the journey, improving function and productivity may be the most effective way to promote some important aspects of animal welfare. For example, alleviating

  11. Developing Deaf Students Fraction Skills Requires Understanding Magnitude and Whole Number Division

    Science.gov (United States)

    Mousley, Keith; Kelly, Ronald R.

    2018-01-01

    Research has shown that fraction magnitude and whole number division are important precursors to learning and understanding fractions. Deaf and hard-of-hearing (DHH) students are consistently challenged with learning fractions from K-12 through college. Sixty DHH college students were tested for both their understanding of magnitude between two…

  12. Concept Mapping as a Tool to Develop and Measure Students' Understanding in Science

    Science.gov (United States)

    Tan, Sema; Erdimez, Omer; Zimmerman, Robert

    2017-01-01

    Concept maps measured a student's understanding of the complexity of concepts, and interrelationships. Novak and Gowin (1984) claimed that the continuous use of concept maps increased the complexity and interconnectedness of students' understanding of relationships between concepts in a particular science domain. This study has two purposes; the…

  13. Challenges of Developing Communicative Interaction in Individuals with Congenital Profound Intellectual and Multiple Disabilities

    Science.gov (United States)

    Blain-Moraes, Stefanie; Chau, Tom

    2012-01-01

    Background: Physiological responses have been used in individuals with acquired disability to enable communicative interaction without motor movement. This study explored four autonomic nervous system (ANS) signals--electrodermal activity, skin temperature, cardiac patterns and respiratory patterns--to enable interaction with individuals born with…

  14. Individual Development of Professionalism in Educational Peer Group Supervision: A Multiple Case Study of GPs

    DEFF Research Database (Denmark)

    Holge-Hazelton, B.; Tulinius, Anne-Charlotte

    2012-01-01

    of professionalism within the individual are, however, difficult to assess. Aim. On the basis of a multiple case study, this paper describes the process of professional learning and challenges for individual GPs, as they take part in supervision groups focusing on children cases. Methods and Results. By using a two...

  15. Assessing Individual Social Capital Capacity: The Development and Validation of a Network Accessibility Scale

    Science.gov (United States)

    Hatala, John-Paul

    2009-01-01

    Any organization that is able to promote the importance of increased levels of social capital and individuals who can leverage and use the resources that exist within the network may experience higher levels of performance. This study sought to add to our knowledge about individuals' accessing social resources for the purpose of accomplishing…

  16. Narrative Content as Described by Individuals with Down Syndrome and Typically Developing Children.

    Science.gov (United States)

    Miles, Sally; Chapman, Robin S.

    2002-01-01

    Narratives of a wordless picture story by 33 individuals with Down syndrome (ages 12-26) and 99 typical children were analyzed. Individuals with Down syndrome expressed more plot line and thematic content and retold more of one of the protagonists' misadventures than the children matched for mean length of utterance. (Contains references.)…

  17. Absorption in Music: Development of a Scale to Identify Individuals with Strong Emotional Responses to Music

    Science.gov (United States)

    Sandstrom, Gillian M.; Russo, Frank A.

    2013-01-01

    Despite the rise in research investigating music and emotion over the last decade, there are no validated measures of individual differences in emotional responses to music. We created the Absorption in Music Scale (AIMS), a 34-item measure of individuals' ability and willingness to allow music to draw them into an emotional experience. It was…

  18. Development and Application of a Two-Tier Diagnostic Test for High School Students' Understanding of Flowering Plant Growth and Development

    Science.gov (United States)

    Lin, Sheau-Wen

    2004-01-01

    This study involved the development and application of a two-tier diagnostic test measuring students' understanding of flowering plant growth and development. The instrument development procedure had three general steps: defining the content boundaries of the test, collecting information on students' misconceptions, and instrument development.…

  19. Understanding the Association of Fatigue With Other Symptoms of Fibromyalgia: Development of a Cluster Model.

    Science.gov (United States)

    Lukkahatai, Nada; Walitt, Brian; Espina, Alexandra; Gelio, Alves; Saligan, Leorey N

    2016-01-01

    To develop a symptoms cluster model that can describe factors of fibromyalgia syndrome (FMS) associated with fatigue severity as reported by the sample and to explore FMS clinical symptom subclusters based on varying symptom intensities. FMS individuals (n = 120, 82% ages 31-60 years, 90% women, 59% white) diagnosed with the 1990 or 2010 American College of Rheumatology diagnostic criteria were enrolled. Participants completed multiple validated self-report questionnaires to measure fatigue, pain, depression, anxiety, pain catastrophizing, daytime sleepiness, cognitive function, and FMS-related polysymptomatic distress. Cluster analysis using SPSS 19.0 and structural equation modeling using AMOS 17.0 were used. Final structural equation modeling the symptoms cluster model showed good fit and revealed that FMS fatigue was associated with widespread pain, symptoms severity, pain intensity, pain interference, cognitive dysfunction, catastrophizing, anxiety, and depression (χ(2)  = 121.72 (98df), P > 0.05, χ(2) /df = 1.242, comparative fit index = 0.982, root mean square error of approximation = 0.045). Two distinct clinical symptom subclusters emerged: subcluster 1 (78% of total subjects), defined by widespread pain, unrefreshed waking, and somatic symptoms, and subcluster 2 (22% of total subjects), defined by fatigue and cognitive dysfunction with pain being a less severe and less widespread occurrence. Overall, subcluster 1 had more intense symptoms than subcluster 2. FMS symptoms may be categorized into 2 clinical subclusters. These findings have implications for an illness whose diagnosis and management are symptom dependent. A longitudinal study capturing the variability in the symptom experience of FMS subjects is warranted. © 2016, American College of Rheumatology.

  20. Development of the understanding of seed recalcitrant and implications for ex situ conservation

    Directory of Open Access Journals (Sweden)

    Norman W. Pammenter

    2013-07-01

    Full Text Available Recalcitrant seeds are shed at high water content, are desiccation sensitive and cannot be stored under conditions conventionally employed for desiccation-tolerant orthodox seeds. Recalcitrant seeds are metabolically active when shed, with high rates of respiration and a high degree of intracellular differentiation. Development grades gradually into germination, with no punctuating quiescent period, and many recalcitrant seeds will germinate if aintained at their shedding water content. Consequently, storage in the hydrated condition is strictly a short-term option only. Although recalcitrant seeds are desiccation sensitive, if excised embryonic axes are dried very rapidly they will survive to lower water contents than those dried slowly. When axes are dried they are initially subject to aqueous-based oxidative degradative processes. Axes dried slowly are exposed to these conditions for an extended period of time, accumulate considerable damage and die at high water contents. Rapidly dried axes accumulate less damage over a shorter period and so survive to lower water contents. The response of excised axes to rapid drying opens up the possibility of cryo-storage. Partial drying reduces the chances of ice formation on subsequent exposure to cryogenic temperatures, and if the drying is rapid, will reduce oxidative damage. Rapid cooling can induce the remaining intracellular water to vitrify, permitting cryo-storage without damaging ice crystal formation. However, because of the highly variable physiology of recalcitrant seeds and axes, detailed protocols have to be established on an individual species basis, guided by these concepts.Key words: Cryopreservation, damage, desiccation, recalcitrant seeds, storage

  1. Rhetorical meta-language to promote the development of students' writing skills and subject matter understanding

    Science.gov (United States)

    Pelger, Susanne; Sigrell, Anders

    2016-01-01

    Background: Feedback is one of the most significant factors for students' development of writing skills. For feedback to be successful, however, students and teachers need a common language - a meta-language - for discussing texts. Not least because in science education such a meta-language might contribute to improve writing training and feedback-giving. Purpose: The aim of this study was to explore students' perception of teachers' feedback given on their texts in two genres, and to suggest how writing training and feedback-giving could become more efficient. Sample: In this study were included 44 degree project students in biology and molecular biology, and 21 supervising teachers at a Swedish university. Design and methods: The study concerned students' writing about their degree projects in two genres: scientific writing and popular science writing. The data consisted of documented teacher feedback on the students' popular science texts. It also included students' and teachers' answers to questionnaires about writing and feedback. All data were collected during the spring of 2012. Teachers' feedback, actual and recalled - by students and teachers, respectively - was analysed and compared using the so-called Canons of rhetoric. Results: While the teachers recalled the given feedback as mainly positive, most students recalled only negative feedback. According to the teachers, suggested improvements concerned firstly the content, and secondly the structure of the text. In contrast, the students mentioned language style first, followed by content. Conclusions: The disagreement between students and teachers regarding how and what feedback was given on the students texts confirm the need of improved strategies for writing training and feedback-giving in science education. We suggest that the rhetorical meta-language might play a crucial role in overcoming the difficulties observed in this study. We also discuss how training of writing skills may contribute to

  2. Proteomics as an approach to the understanding of the molecular physiology of fruit development and ripening.

    Science.gov (United States)

    Palma, José M; Corpas, Francisco J; del Río, Luís A

    2011-08-12

    Fruit ripening is a developmental complex process which occurs in higher plants and involves a number of stages displayed from immature to mature fruits that depend on the plant species and the environmental conditions. Nowadays, the importance of fruit ripening comes mainly from the link between this physiological process in plants and the economic repercussions as a result of one of the human activities, the agricultural industry. In most cases, fruit ripening is accompanied by colour changes due to different pigment content and increases in sugar levels, among others. Major physiological modifications that affect colour, texture, flavour, and aroma are under the control of both external (light and temperature) and internal (developmental gene regulation and hormonal control) factors. Due to the huge amount of metabolic changes that take place during ripening in fruits from higher plants, the accomplishment of new throughput methods which can provide a global evaluation of this process would be desirable. Differential proteomics of immature and mature fruits would be a useful tool to gain information on the molecular changes which occur during ripening, but also the investigation of fruits at different ripening stages will provide a dynamic picture of the whole transformation of fruits. This subject is furthermore of great interest as many fruits are essential for human nutrition. Thus far different maturation profiles have been reported specific for each crop species. In this work, a thorough review of the proteomic database from fruit development and maturation of important crop species will be updated to understand the molecular physiology of fruits at ripening stages. Copyright © 2011 Elsevier B.V. All rights reserved.

  3. Modeling the epigenetic attractors landscape: toward a post-genomic mechanistic understanding of development

    Science.gov (United States)

    Davila-Velderrain, Jose; Martinez-Garcia, Juan C.; Alvarez-Buylla, Elena R.

    2015-01-01

    Robust temporal and spatial patterns of cell types emerge in the course of normal development in multicellular organisms. The onset of degenerative diseases may result from altered cell fate decisions that give rise to pathological phenotypes. Complex networks of genetic and non-genetic components underlie such normal and altered morphogenetic patterns. Here we focus on the networks of regulatory interactions involved in cell-fate decisions. Such networks modeled as dynamical non-linear systems attain particular stable configurations on gene activity that have been interpreted as cell-fate states. The network structure also restricts the most probable transition patterns among such states. The so-called Epigenetic Landscape (EL), originally proposed by C. H. Waddington, was an early attempt to conceptually explain the emergence of developmental choices as the result of intrinsic constraints (regulatory interactions) shaped during evolution. Thanks to the wealth of molecular genetic and genomic studies, we are now able to postulate gene regulatory networks (GRN) grounded on experimental data, and to derive EL models for specific cases. This, in turn, has motivated several mathematical and computational modeling approaches inspired by the EL concept, that may be useful tools to understand and predict cell-fate decisions and emerging patterns. In order to distinguish between the classical metaphorical EL proposal of Waddington, we refer to the Epigenetic Attractors Landscape (EAL), a proposal that is formally framed in the context of GRNs and dynamical systems theory. In this review we discuss recent EAL modeling strategies, their conceptual basis and their application in studying the emergence of both normal and pathological developmental processes. In addition, we discuss how model predictions can shed light into rational strategies for cell fate regulation, and we point to challenges ahead. PMID:25954305

  4. Development and understanding of multifunctional gold nanorings for photodynamic therapy of cancer

    Science.gov (United States)

    Hu, Yue

    Gold nanostructures of various geometries and dimensions are being broadly explored in the fast expanding field of nanomedicine due to the unusual combination of biocompatibility, versatility of surface functionalization, and localized surface-plasmon resonance (LSPR). Examples of relevant applications include biomedical imaging, clinical diagnostics and therapeutics. Gold nanorings (Au NRs) are of particular interest because of their intricate structure and LSPR tunability over a wide wavelength range. A solution-based synthesis approach is yet to be developed, however, to allow exploration of Au NRs for basic and applied studies. This dissertation focuses on the fabrication, characterization, and evaluation of colloidal Au NRs for enhanced photodynamic therapy (PDT) of breast cancer cells. We have developed a novel synthesis strategy and associated pathways toward Au NRs by galvanic replacement reaction of Co nanoparticles (Co NPs) in HAuCl4 solution. We have shown that surface-chemistry mediated particle-particle interaction of the Co NPs that leads to their 1D chain-like assembly as sacrificial template is critically important for the growth of Au NRs. Otherwise, Au nanoshells or Au nanotubes may result. The Au NRs exhibit tunable LSPR wavelengths from visible to near-infrared (NIR) region via varying the aspect ratio, in agreement with our theoretical calculations using the finite-difference time domain (FDTD) method. A layer-by-layer (LbL) assembly method was used to load Al(III) phthalocyanine chloride tetrasulfonic acid (AlPcS4) photosensitizer (PS) onto the surface of Au NRs. We have revealed that the photosensitivity of AlPcS4 can be quenched unless desorbed from the surface of Au NRs in the cellular compartment. An eight-fold increase in PDT killing efficiency of human breast cancer cells (MDA-MB-231) has been achieved using LbL-assembled AlPcS4-Au NR complexes in comparison to AlPcS4 only or the mixture of AlPcS 4 and Au NRs. This strategy allows

  5. Understanding Nanoemulsion Formation and Developing a Procedure for Porous Material Growth using Assembled Nanoemulsions

    Science.gov (United States)

    Yeranossian, Vahagn Frounzig

    Nanoemulsions as an emerging technology have found many applications in consumer products, drug delivery, and even particle formation. However, knowledge gaps exist in how some of these emulsions are formed, specifically what pathways are traversed to reach the final state. Moreover, how these pathways affect the final properties of the nanoemulsions would affect the applications that these droplets possess. Some nanoemulsions possess unique properties, including the assembly of droplets. While the assembly of droplets is being studied in the Helgeson lab, work must be done to understand how the assembly itself could be used to control the growth of porous materials, such a hydrogels. Thus, this thesis aims to address two factors of nanoemulsions: the formation of water-in-oil nanoemulsions and the use of assemblying droplets in oil-in-water nanoemulsions to form macroporous hydrogels. To elucidate the formation mechanism of water-in-oil nanoemulsions, a combination of dynamic light scattering and small angle neutron scattering were used to study the intermediate and final states of the nanoemulsion during its formation. These nanoemulsions were prepared by slowly adding water to an oil and surfactant mixture and were diluted to effectively measure using scattering techniques without multiple scattering events. To develop a procedure to use assembled nanoemulsions for the growth of porous materials, a combination of optical microscopy and diffusional studies were employed. Optical microscopy images taken at various stages of the procedure help elucidate how the pore sizes of the final porous material is related to the droplet-rich domains of the assembled nanoemulsion. Meanwhile, diffusional measurements help confirm the size and interconnectedness of the macropores. From the work done in the completion of my thesis, the formation mechanism of the water-in-oil nanoemulsion studied has been elucidated. The neutron scattering measurements show that during the

  6. Geographic Information System Incorporated into Earth Science Classrooms to Enhance Individual Learning Development with Interconnected Concepts

    Science.gov (United States)

    Garifo, Mary Anna

    2017-04-01

    Geographic Information System, GIS, is a powerful tool and when incorporated into Earth Science classrooms, can enhance and empower students' engagement in their learning. Through utilization of GIS, students can process what they are learning in a spatially orientated method, which allows them to make connections among different related concepts. For example, if students are given a map in a GIS software with multiple layers of data on earthquakes, plate technics, and volcanoes then they can manipulate this information to come up with their own patterns. Through allowing students to develop their spatial recognition of where the Earth's plate boundaries are and where earthquakes have occurred, students can see how these two concepts are connected. In a guided but exploratory activity, students would be given multiple different websites that they could explore to research what different type of plates there are while they are working simultaneously with the GIS software. Using a plate technics layer, including data on type of boundary, students can explore and estimate which direction the plates are moving. When they look up convergent boundaries and see that the oceanic plates submerge under continental plates they can see where volcanic chains might be. Once they understand this in a spatial way, students can predict where they think volcanoes could be, based on where convergent boundaries are. When they manipulate the volcanic layer and see abnormalities to what they just learned, it will cause them to have cognitive dissonance, which will force them into seeking further understanding. The concept of a hot spot can then be introduced to resolve the cognitive dissonance and emphasis the idea that plates we live on are moving. Concepts can further be developed through GIS by showing how the strength and frequency of earthquakes are related to the level of activity at the plate boundary. This can be done by manipulating the map layer that represents earthquakes so

  7. Multimodal Learning and Intelligent Prediction of Symptom Development in Individual Parkinson’s Patients

    Directory of Open Access Journals (Sweden)

    Andrzej W. Przybyszewski

    2016-09-01

    Full Text Available We still do not know how the brain and its computations are affected by nerve cell deaths and their compensatory learning processes, as these develop in neurodegenerative diseases (ND. Compensatory learning processes are ND symptoms usually observed at a point when the disease has already affected large parts of the brain. We can register symptoms of ND such as motor and/or mental disorders (dementias and even provide symptomatic relief, though the structural effects of these are in most cases not yet understood. It is very important to obtain early diagnosis, which can provide several years in which we can monitor and partly compensate for the disease’s symptoms, with the help of various therapies. In the case of Parkinson’s disease (PD, in addition to classical neurological tests, measurements of eye movements are diagnostic. We have performed measurements of latency, amplitude, and duration in reflexive saccades (RS of PD patients. We have compared the results of our measurement-based diagnoses with standard neurological ones. The purpose of our work was to classify how condition attributes predict the neurologist’s diagnosis. For n = 10 patients, the patient age and parameters based on RS gave a global accuracy in predictions of neurological symptoms in individual patients of about 80%. Further, by adding three attributes partly related to patient ‘well-being’ scores, our prediction accuracies increased to 90%. Our predictive algorithms use rough set theory, which we have compared with other classifiers such as Naïve Bayes, Decision Trees/Tables, and Random Forests (implemented in KNIME/WEKA. We have demonstrated that RS are powerful biomarkers for assessment of symptom progression in PD.

  8. Develop a quantitative understanding of rockmass behaviour near excavations in deep mines, part 2

    CSIR Research Space (South Africa)

    Napier, JAL

    1995-12-01

    Full Text Available Modelling of failure processes in rock is an essential adjustment to the analysis of observations of underground rock fracturing. The identification of mechanisms of deformation represents a basic step in understanding of rock mass behaviour...

  9. Development and understanding of new membranes based on aromatic polymers and heterocycles for fuel cells

    Science.gov (United States)

    Li, Wen

    Direct methanol fuel cells (DMFC) are appealing as a power source for portable devices as they do not require recharging with an electrical outlet. However, the DMFC technology is confronted with the high crossover of methanol fuel from the anode to the cathode through the currently used Nafion membrane, which not only wastes the fuel but also poisons the cathode platinum catalyst. With an aim to overcome the problems encountered with the Nafion membrane, this dissertation focuses on the design and development of new polymeric membrane materials for DMFC and a fundamental understanding of their structure-property-performance relationships. Several polymeric blend membranes based on acid-base interactions between an aromatic acidic polymer such as sulfonated ploy(ether ether ketone) (SPEEK) and an aromatic basic polymer such as heterocycle tethered poly(sulfone) (PSf) have been explored. Various heterochylces like nitro-benzimidazole (NBIm), 1H-Perimidine (PImd), and 5-amino-benzotriazole (BTraz) have been tethered to PSf to understand the influence of pKa values and the size of the hetrocycles. The blend membranes show lower methanol crossover and better performance in DMFC than plain SPEEK due to an enhancement in proton conductivity through acid-base interactions and an insertion of the heterocycle side groups into the ionic clusters of SPEEK as indicated by small angle X-ray scattering and TEM data. The SPEEK/PSf-PImd blend membrane shows the lowest methanol crossover due to the larger size of the side groups, while the SPEEK/PSf-BTraz blend membrane shows the highest proton conductivity and maximum power density. To further investigate the methanol-blocking effect of the heterocycles, N,N'-Bis-(1H-benzimidazol-2-yl)-isophthalamide (BBImIP) having two amino-benzimidazole groups bonded to a phenyl ring has been incorporated into sulfonated polysulfone (SPSf) and SPEEK membranes. With two 2-amino-benzimidazole groups, which could greatly increase the proton

  10. Exemplary, New Teachers' Perspectives on Teaching Second-Language Learners and Developing Academic Language: An Embodied Understanding of Practice Framework

    Science.gov (United States)

    Gomez, Maria-Cecilia

    2013-01-01

    This qualitative, longitudinal study examines the perspectives on professional development of a group of exemplary, new secondary teachers of English Language Arts and Spanish (n = 4). This study explores the teachers' development through the lens of the "embodied understanding of practice" (EUP), a novel theoretical framework of…

  11. On the Importance of Comparative Research for the Understanding of Human Behavior and Development: A Reply to Gottlieb & Lickliter (2004)

    Science.gov (United States)

    Maestripieri, Dario

    2005-01-01

    Comparative behavioral research is important for a number of reasons and can contribute to the understanding of human behavior and development in many different ways. Research with animal models of human behavior and development can be a source not only of general principles and testable hypotheses but also of empirical information that may be…

  12. Open Tools for Integrated Modelling to Understand SDG development - The OPTIMUS program

    Science.gov (United States)

    Howells, Mark; Zepeda, Eduardo; Rogner, H. Holger; Sanchez, Marco; Roehrl, Alexander; Cicowiez, Matrin; Mentis, Dimitris; Korkevelos, Alexandros; Taliotis, Constantinos; Broad, Oliver; Alfstad, Thomas

    2016-04-01

    The recently adopted Sustainable Development Goals (SDGs) - a set of 17 measurable and time-bound goals with 169 associated targets for 2030 - are highly inclusive challenges before the world community ranging from eliminating poverty to human rights, inequality, a secure world and protection of the environment. Each individual goal or target by themselves present enormous tasks, taken together they are overwhelming. There strong and weak interlinkages, hence trade-offs and complementarities among goals and targets. Some targets may affect several goals while other goals and targets may conflict or be mutually exclusive (Ref). Meeting each of these requires the judicious exploitation of resource, with energy playing an important role. Such complexity demands to be addressed in an integrated way using systems analysis tools to support informed policy formulation, planning, allocation of scarce resources, monitoring progress, effectiveness and review at different scales. There is no one size fits all methodology that conceivably could include all goal and targets simultaneously. But there are methodologies encapsulating critical subsets of the goal and targets with strong interlinkages with a 'soft' reflection on the weak interlinkages. Universal food security or sustainable energy for all inherently support goals and targets on human rights and equality but possibly at the cost of biodiversity or desertification. Integrated analysis and planning tools are not yet commonplace at national universities - or indeed in many policy making organs. What is needed is a fundamental realignment of institutions and integrations of their planning processes and decision making. We introduce a series of open source tools to support the SDG planning and implementation process. The Global User-friendly CLEW Open Source (GLUCOSE) tool optimizes resource interactions and constraints; The Global Electrification Tool kit (GETit) provides the first global spatially explicit

  13. Understanding the Role of O-GlcNAc Modifications in Plant Development

    Energy Technology Data Exchange (ETDEWEB)

    Olszewski, Neil, E.

    2011-06-16

    This project has contributed towards understanding the role of O-GlcNAc (O-linked N-acetylglucosamine) transferases (OGTs) in plants. Through analyses of single and double mutants, we have investigated the unique and overlapping functions of SECRET AGENT (SEC) and SPINDLY (SPY), the arabidopsis OGTs. This work showed that SEC functions as negative regulators of the long-day flowering pathway. SEC also has a positive role in regulation of rosette. An E. coli co-expression system that allows potential substrates to be co-expressed with and O-GlcNAc modified by SEC was developed. We showed that SEC is a bona fide OGT that modifies itself with single O-linked GlcNAc(s). Using this system, we tested a number of proteins that were hypothesized to be substrates of SEC and identified a number of substrates include GIGANTEA (GI), a component of the long day flowering pathway. The hypothesis that O-GlcNAc modification controls GI activity was tested by first mapping where E. coli-expressed SEC modifies GI and then assessing the activity of a non-modifiable mutant form of GI. The activity of the mutant form of GI was indistinguishable from that of wild type suggesting that either O-GlcNAc does not regulate GI activity or that additional modification sites exist on GI. In collaboration with Dr. Juan Antonio Garcia at Universidad Autónoma de Madrid the role of O-GlcNAc modification of the plum pox virus coat protein (PPV-CP) was investigated. SEC was shown to O-GlcNAc modify PPV-CP and the modification was shown to facilitate the infection process. E. coli-expressed SEC was shown to modify the same PPV-CP sites that are modified in plants. SEC has a large protein interaction domain called the TPR domain that has been hypothesized to have a role in determining the substrate specificity of the enzyme and/or to regulate its activity. A mutational analysis of the TPR domain did not find evidence for a role in substrate specificity but did obtain evidence that the domain regulates

  14. Serum Vaspin Levels Are Associated with the Development of Clinically Manifest Arthritis in Autoantibody-Positive Individuals

    NARCIS (Netherlands)

    Maijer, Karen I.; Neumann, Elena; Müller-Ladner, Ulf; Drop, Daniël A. C. A. D.; Ramwadhdoebe, Tamara H.; Choi, Ivy Y. K.; Gerlag, Daniëlle M.; de Hair, Maria J. H.; Tak, Paul P.

    2015-01-01

    We have previously shown that overweight may increase the risk of developing rheumatoid arthritis (RA) in autoantibody positive individuals. Adipose tissue could contribute to the development of RA by production of various bioactive peptides. Therefore, we examined levels of adipokines in serum and

  15. Advancement Via Individual Determination (AVID) Professional Development as a Predictor of Teacher Leadership in the United States

    Science.gov (United States)

    Watt, Karen M.; Huerta, Jeffery; Mills, Shirley J.

    2010-01-01

    This study expands on the work of Huerta "et al." (2008) by reexamining the relationship between professional development and teacher leadership using more comprehensive measures of each. By confirming Huerta "et al"'s (2008) finding that Advancement Via Individual Determination (AVID) professional development is a significant predictor of teacher…

  16. THE INFLUENCE OF INDIVIDUAL KNOWLEDGE AND WORK TEAM DEVELOPMENT TO THE MANUFACTURING COMPANY PERFORMANCE OF IN EAST JAVA

    Directory of Open Access Journals (Sweden)

    Widjojo Suprapto

    2017-03-01

    Full Text Available Individual knowledge is the fundamental human capital to contribute to the greatness of the company.The personal capability and competence should be dispersed to other individuals within the organization toform a work team that is reliable and motivated so that each individual can easily do the workcommunication. As a result, it gives an impact on the flexibility of working people and eventually canimprove the company performance. The data are collected by questionnaires that are distributed to 90industrial practitioners, with the 86 completed data that can be further processed. The result of this studystates that the individual knowledge influences strongly on the development of the competent work team, andenhances the collaboration and communication process. The development of the work teams in the companyaffects the collaboration, communication, and effectiveness of the work teams. Finally, the cooperation andcommunication in the work place and the effectiveness of the work teams together improve the companyperformance.

  17. Neuroimaging Studies of Normal Brain Development and Their Relevance for Understanding Childhood Neuropsychiatric Disorders

    Science.gov (United States)

    Marsh, Rachel; Gerber, Andrew J.; Peterson, Bradley S.

    2008-01-01

    Neuroimaging findings which identify normal brain development trajectories are presented. Results show that early brain development begins with the neural tube formation and ends with myelintation. How disturbances in brain development patterns are related to childhood psychiatric disorders is examined.

  18. Developing a new individualized 3-node model for evaluating the effects of personal factors on thermal sensation.

    Science.gov (United States)

    Davoodi, Farzin; Hasanzadeh, Hasan; Alireza Zolfaghari, Seyed; Maerefat, Mehdi

    2017-10-01

    Individual differences, such as weight, height, gender, age, and Basal Metabolic Rate (BMR), between human subjects can significantly affect body thermoregulatory mechanisms. Therefore, application of common population-based thermal comfort models cannot provide accurate results for an individual's thermal sensation. Based on the standard thermal models, including those of Fanger and Gagge, individual parameters are not considered in the evaluation of thermal sensations. Thus, these simplified standard models have some limitations under varied individual conditions. In this study, a new individualized thermal comfort model is presented on the basis of a simplified 3-node model. This model was developed by regarding the effects of individual characteristics, such as age, gender, Body Mass Index (BMI), and BMR on the thermal sensations of the bare and clothed parts of the body. A good agreement was found in the current model, which was verified based on the experimental data. In conclusion, the results indicated that the mean error in the prediction of skin temperature decreased from 1.2°C to 0.4°C when using the new individual model instead of a non-individualized 3-node model. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. Individualized 3D Reconstruction of Normal Tissue Dose for Patients With Long-term Follow-up: A Step Toward Understanding Dose Risk for Late Toxicity

    Energy Technology Data Exchange (ETDEWEB)

    Ng, Angela [Radiation Medicine Program, Princess Margaret Hospital, Toronto, Ontario (Canada); Brock, Kristy K.; Sharpe, Michael B. [Radiation Medicine Program, Princess Margaret Hospital, Toronto, Ontario (Canada); Department of Radiation Oncology, University of Toronto, Toronto, Ontario (Canada); Moseley, Joanne L. [Radiation Medicine Program, Princess Margaret Hospital, Toronto, Ontario (Canada); Craig, Tim [Radiation Medicine Program, Princess Margaret Hospital, Toronto, Ontario (Canada); Department of Radiation Oncology, University of Toronto, Toronto, Ontario (Canada); Hodgson, David C., E-mail: David.Hodgson@rmp.uhn.on.ca [Radiation Medicine Program, Princess Margaret Hospital, Toronto, Ontario (Canada); Department of Radiation Oncology, University of Toronto, Toronto, Ontario (Canada)

    2012-11-15

    Purpose: Understanding the relationship between normal tissue dose and delayed radiation toxicity is an important component of developing more effective radiation therapy. Late outcome data are generally available only for patients who have undergone 2-dimensional (2D) treatment plans. The purpose of this study was to evaluate the accuracy of 3D normal tissue dosimetry derived from reconstructed 2D treatment plans in Hodgkin's lymphoma (HL) patients. Methods and Materials: Three-dimensional lung, heart, and breast volumes were reconstructed from 2D planning radiographs for HL patients who received mediastinal radiation therapy. For each organ, a reference 3D organ was modified with patient-specific structural information, using deformable image processing software. Radiation therapy plans were reconstructed by applying treatment parameters obtained from patient records to the reconstructed 3D volumes. For each reconstructed organ mean dose (D{sub mean}) and volumes covered by at least 5 Gy (V{sub 5}) and 20Gy (V{sub 20}) were calculated. This process was performed for 15 patients who had both 2D and 3D planning data available to compare the reconstructed normal tissue doses with those derived from the primary CT planning data and also for 10 historically treated patients with only 2D imaging available. Results: For patients with 3D planning data, the normal tissue doses could be reconstructed accurately using 2D planning data. Median differences in D{sub mean} between reconstructed and actual plans were 0.18 Gy (lungs), -0.15 Gy (heart), and 0.30 Gy (breasts). Median difference in V{sub 5} and V{sub 20} were less than 2% for each organ. Reconstructed 3D dosimetry was substantially higher in historical mantle-field treatments than contemporary involved-field mediastinal treatments: average D{sub mean} values were 15.2 Gy vs 10.6 Gy (lungs), 27.0 Gy vs 14.3 Gy (heart), and 8.0 Gy vs 3.2 Gy (breasts). Conclusions: Three-dimensional reconstruction of absorbed dose

  20. Developing Conceptual Understanding of Natural Selection: The Role of Interest, Efficacy, and Basic Prior Knowledge

    Science.gov (United States)

    Linnenbrink-Garcia, Lisa; Pugh, Kevin J.; Koskey, Kristin L. K.; Stewart, Victoria C.

    2012-01-01

    Changes in high school students' (n = 94) conceptions of natural selection were examined as a function of motivational beliefs (individual interest, academic self-efficacy), basic prior knowledge, and gender across three assessments (pre, post, follow-up). Results from variable-centered analyses suggested that these variables had relatively little…

  1. Post-Institutionalized Chinese and Eastern European Children: Heterogeneity in the Development of Emotion Understanding

    Science.gov (United States)

    Camras, Linda A.; Perlman, Susan B.; Fries, Alison B. Wismer; Pollak, Seth D.

    2006-01-01

    Post-institutionalized Chinese and Eastern European children participated in two emotion understanding tasks. In one task, children selected facial expressions corresponding to four emotion labels (happy, sad, angry, scared). The second task required children to match facial expressions to stories describing situations for these emotions. While…

  2. Differentiating Processes of Control and Understanding in the Early Development of Emotion and Cognition

    Science.gov (United States)

    Blankson, A. Nayena; O'Brien, Marion; Leerkes, Esther M.; Marcovitch, Stuart; Calkins, Susan D.

    2012-01-01

    In this study, we examined the hypothesis that preschoolers' performance on emotion and cognitive tasks is organized into discrete processes of control and understanding within the domains of emotion and cognition. Additionally, we examined the relations among component processes using mother report, behavioral observation, and physiological…

  3. Professional Development Aligned with AP Chemistry Curriculum: Promoting Science Practices and Facilitating Enduring Conceptual Understanding

    Science.gov (United States)

    Herrington, Deborah G.; Yezierski, Ellen J.

    2014-01-01

    The recent revisions to the advanced placement (AP) chemistry curriculum promote deep conceptual understanding of chemistry content over more rote memorization of facts and algorithmic problem solving. For many teachers, this will mean moving away from traditional worksheets and verification lab activities that they have used to address the vast…

  4. Developing a Theoretical Framework for Examining Student Understanding of Fractional Concepts: An Historical Accounting

    Science.gov (United States)

    Cooper, Susan M.; Wilkerson, Trena L.; Montgomery, Mark; Mechell, Sara; Arterbury, Kristin; Moore, Sherrie

    2012-01-01

    In 2007, a group of mathematics educators and researchers met to examine rational numbers and why children have such an issue with them. An extensive review of the literature on fractional understanding was conducted. The ideas in that literature were then consolidated into a theoretical framework for examining fractions. Once that theoretical…

  5. 'Feeling good' unpacked : Developing design tools to facilitate a differentiated understanding of positive emotions

    NARCIS (Netherlands)

    Yoon, J.; Pohlmeyer, A.E.; Desmet, P.M.A.; Desmet, P.M.A.; Fokkinga, S.F.; Ludden, G.D.S.; Cila, N.; Van Zuthem, H.

    2016-01-01

    The range of positive emotions experienced in human-product interactions is diverse, and understanding the differences and similarities between these positive emotions can support emotion-driven design. Yet, there is little knowledge about what kind of tool would be effective to leverage

  6. Developing an Organizational Understanding of Faculty Mentoring Programs in Academic Medicine in Major American Research Universities

    Science.gov (United States)

    Fischer Zellers, Darlene

    2013-01-01

    This study examines the organizational and contextual factors associated with faculty mentoring programs in academic medicine within major research institutions in the United States, and explores the usefulness of organizational behavior theory in understanding these relationships. To date, many formal faculty mentoring programs are in operation…

  7. Understanding Pictures: A Study in the Design of Appropriate Visual Materials for Education in Developing Countries.

    Science.gov (United States)

    Walker, David Addison

    The document attempts to integrate aspects of two lines of research relating to picture recognition and the comprehension of pictorial space. It also describes an empirical study carried out in Nepal which tested rural adult subjects' understanding of topological, euclidean, and projective concepts in regard to real objects and to pictures. The…

  8. Developing Essential Understanding of Multiplication and Division for Teaching Mathematics in Grades 3-5

    Science.gov (United States)

    Otto, Albert; Caldwell, Janet; Hancock, Sarah Wallus; Zbiek, Rose Mary

    2011-01-01

    This book identifies and examines two big ideas and related essential understandings for teaching multiplication and division in grades 3-5. Big Idea 1 captures the notion that multiplication is usefully defined as a scalar operation. Problem situations modeled by multiplication have an element that represents the scalar and an element that…

  9. Developing critical understanding by teaching action research to undergraduate psychology students

    NARCIS (Netherlands)

    Dr. Gaby Jacobs; Prof. dr. Michael Murray

    2010-01-01

    Action research assumes the active engagement of the stakeholders, such as the community, in the research, and a multiple level process of reflection in order to evaluate and monitor the actions taken. This makes action research a suitable methodology to increase critical understanding of the

  10. Understanding the link between GMP and dough: From glutenin particles in flour towards developed dough

    NARCIS (Netherlands)

    Don, C.; Lichtendonk, W.J.; Plijter, J.J.; Hamer, R.J.

    2003-01-01

    Clear correlations exist for glutenin macropolymer (GMP) quantity and rheological properties vs. wheat quality and dough rheological properties, but real insight in understanding these links is still missing. The observation that GMP consists of glutenin particles opens up new possibilities to

  11. The Development of Understanding of Evidence in Pre-University Biology Education in the Netherlands

    NARCIS (Netherlands)

    van der Schalk, H; van der Schee, J.A.; Boersma, Th.

    2013-01-01

    Ensuring the quality of investigations requires the understanding of procedures by which empirical evidence is obtained. This can be interpreted as becoming aware of and using criteria for evidence in one's mental structure. The question is whether this process can be observed in practice. In two

  12. Developing Students' Understanding of Industrially Relevant Economic and Life Cycle Assessments

    Science.gov (United States)

    Bode, Claudia J.; Chapman, Clint; Pennybaker, Atherly; Subramaniam, Bala

    2017-01-01

    Training future leaders to understand life cycle assessment data is critical for effective research, business, and sociopolitical decision-making. However, the technical nature of these life cycle reports often makes them challenging for students and other nonexperts to comprehend. Therefore, we outline here the key takeaways from recent economic…

  13. Development of psychosocial case studies by students to improve their ability to understand and analyze human behavior

    OpenAIRE

    Saldaña, Omar; Rodríguez Carballeira, Álvaro; Espelt, Esteve; Jiménez, Yirsa; Porrúa, Clara; Escartín Solanelles, Jordi; Castrechini Trotta, Ángela; Codina, Núria (Codina Mata); Pestana, José Vicente; Vidal i Moranta, Tomeu

    2015-01-01

    This study presents an active learning methodology based on the development and analysis of case studies by college students and explores its effects on academic performance and on students' capacity of understanding and analysing human behaviour. A group of 54 students who were taking the course Social Psychology at the University of Barcelona developed written stories where psychosocial concepts were represented. Results showed that participants, after developing their own case studies, imp...

  14. NAVIGATION AIDS AS TOOLS TO SUPPORT THE DEVELOPMENT OF COMPETENCES IN THE CONDITIONS OF REALIZATION OF INDIVIDUAL EDUCATIONAL TRAJECTORY

    Directory of Open Access Journals (Sweden)

    E. F. Zeer

    2017-01-01

    Full Text Available Introduction. Continuing education or «education through all life» is required of the person by modern realities of the information, quickly changing society; thus, continuing education is carried out on a development trajectory, individual for each person. Maintenance of such educational process needs effective tools. The relevance of its development caused the research presented in the publication.The aim is to show the possibilities of navigation aids during realization of individual routes of the training conforming to federal state educational standards and considering the purposes and interests of each separately taken personality.Methodology and research methods. The leading methodological basis is personality-oriented approach in the implementation of individual educational trajectory. Logical-pedagogical analysis of students’ individual educational trajectory progress is used.Results and scientific novelty. The interrelation of the concepts «individual educational trajectory» and «individual educational route» is revealed. The conceptual model of maintenance of an individual educational trajectory as a set of reference points of mastering of competences necessary for the expert is offered. Navigators of educational process and cases of individual educational achievements assessment act as didactic means in model. It is shown whence application of components of models allows to: organize the professional orientation actions more effectively; exercise entrance control of knowledge prior to training; control actions during vocational training; correlate an individual trajectory of training to the standard; have a guide when studying disciplines of various cycles, when passing educational and production training, protection of final qualification work; finally, it is possible for a pupil to carry out self-estimation of the acquired competences.Practical significance. The materials of the present publication will be useful to

  15. Development and application of virtual reality technology to improve hand use and gait of individuals post-stroke.

    Science.gov (United States)

    Deutsch, Judith E; Merians, Alma S; Adamovich, Serge; Poizner, Howard; Burdea, Grigore C

    2004-01-01

    Development and application of virtual reality (VR) systems for rehabilitation is an iterative process produced by collaboration of an inter-disciplinary team of engineers, neuroscientists and clinician-scientists. In this paper the use of virtual reality technology for the rehabilitation of individuals post-stroke is described. The development of the hardware is based on principles of motor control. Development of the software uses findings from the enrichment and motor plasticity and training literatures as well as principles of motor learning. Virtual environments are created to afford individuals post-stroke opportunities to practice tasks for which they require rehabilitation. These tasks, related to hand function and gait, are trained both at the impairment and functional level. The training engages users to allow for the repetitive intensive practice required for behavioral motor plasticity. Results from a series of upper and lower extremity studies indicate that use of VR technology to augment rehabilitation of individuals post-stroke merits further study.

  16. Effects of Web-Based Collaborative Writing on Individual L2 Writing Development

    Science.gov (United States)

    Bikowski, Dawn; Vithanage, Ramyadarshanie

    2016-01-01

    This study investigated the effect of repeated in-class web-based collaborative writing tasks on second language writers' (L2) individual writing scores. A pre-test post-test research model was used in addition to participant surveys, class observations, and teacher interviews. Participants included 59 L2 writers in a writing class at a large U.S.…

  17. Individually Prescribed Instruction--Mathematics (IPI--Math). Product Development Report No. 17.

    Science.gov (United States)

    Jung, Steven M.

    This report summarizes the mathematics component of Individually Prescribed Instruction (IPI). The first section outlines the overall goals, specific objectives, and philosophy of IPI; the organization of the materials; and the procedures for their use, with emphasis on the altered role of both students and teachers. The next section describes the…

  18. Individual career initiatives and their influence upon professional expertise development throughout the career

    NARCIS (Netherlands)

    van der Heijden, Beatrice

    2002-01-01

    The present study describes the relationship between three individual predictor variables and the degree of professional expertise of higher level employees in three different career stages. Professional expertise is operationalised by means of five dimensions, i.e. knowledge, meta-cognitive

  19. Long‐term developments in individual work behaviour: Patterns of stability and change

    NARCIS (Netherlands)

    Annet de Lange; Beatrice van der Heijden; René Schalk; Marc van Veldhoven

    2011-01-01

    In the current era, characterized by dynamic societal, technological, and economic changes as well as an increasing diversity in the workforce, previous approaches to individual work behaviour are being challenged (Schalk et al. 2010). Demographic trends in the working population, for example,

  20. Families and Individual Development: Provocations from the Field of Family Therapy.

    Science.gov (United States)

    Minuchin, Patricia

    1985-01-01

    Focuses on systems theory as the paradigm underlying family therapy and considers the implications of this framework for conceptions of the individual, the study of parent-child interaction, and new research formulations and areas of study. Considers trends in the developmental field that move toward such formulations. (RH)