Sample records for understanding irregular coevolutionary

  1. Venom Resistance as a Model for Understanding the Molecular Basis of Complex Coevolutionary Adaptations. (United States)

    Holding, Matthew L; Drabeck, Danielle H; Jansa, Sharon A; Gibbs, H Lisle


    SynopsisVenom and venom resistance are molecular phenotypes widely considered to have diversified through coevolution between predators and prey. However, while evolutionary and functional studies on venom have been extensive, little is known about the molecular basis, variation, and complexity of venom resistance. We review known mechanisms of venom resistance and relate these mechanisms to their predicted impact on coevolutionary dynamics with venomous enemies. We then describe two conceptual approaches which can be used to examine venom/resistance systems. At the intraspecific level, tests of local adaptation in venom and resistance phenotypes can identify the functional mechanisms governing the outcomes of coevolution. At deeper evolutionary timescales, the combination of phylogenetically informed analyses of protein evolution coupled with studies of protein function promise to elucidate the mode and tempo of evolutionary change on potentially coevolving genes. We highlight case studies that use each approach to extend our knowledge of these systems as well as address larger questions about coevolutionary dynamics. We argue that resistance and venom are phenotypic traits which hold exceptional promise for investigating the mechanisms, dynamics, and outcomes of coevolution at the molecular level. Furthermore, extending the understanding of single gene-for-gene interactions to the whole resistance and venom phenotypes may provide a model system for examining the molecular and evolutionary dynamics of complex multi-gene interactions. © The Author 2016. Published by Oxford University Press on behalf of the Society for Integrative and Comparative Biology. All rights reserved. For permissions please email:

  2. Understanding herding based on a co-evolutionary model for strategy and game structure

    International Nuclear Information System (INIS)

    Wang, Tao; Huang, Keke; Cheng, Yuan; Zheng, Xiaoping


    Highlights: •We model herding effect in emergency from perspective of evolutionary game theory. •Rational subpopulation survives only when the game parameter is significantly large. •Herding effect may arise if the relative rewarding for rational agents is small. •Increasing the relative rewarding for rational agents will prevent herding effect. •The evolution result is unstable if the game parameter approaches critical points. -- Abstract: So far, there has been no conclusion on the mechanism for herding, which is often discussed in the academia. Assuming escaping behavior of individuals in emergency is rational rather than out of panic according to recent findings in social psychology, we investigate the behavioral evolution of large crowds from the perspective of evolutionary game theory. Specifically, evolution of the whole population divided into two subpopulations, namely the co-evolution of strategy and game structure, is numerically simulated based on the game theoretical models built and the evolutionary rule designed, and a series of phenomena including extinction of one subpopulation and herding effect are predicted in the proposed framework. Furthermore, if the rewarding for rational agents becomes significantly larger than that for emotional ones, herding effect will disappear. It is exciting that some phase transition points with interesting properties for the system can be found. In addition, our model framework is able to explain the fact that it is difficult for mavericks to prevail in society. The current results of this work will be helpful in understanding and restraining herding effect in real life

  3. Coevolutionary modeling in network formation

    KAUST Repository

    Al-Shyoukh, Ibrahim


    Network coevolution, the process of network topology evolution in feedback with dynamical processes over the network nodes, is a common feature of many engineered and natural networks. In such settings, the change in network topology occurs at a comparable time scale to nodal dynamics. Coevolutionary modeling offers the possibility to better understand how and why network structures emerge. For example, social networks can exhibit a variety of structures, ranging from almost uniform to scale-free degree distributions. While current models of network formation can reproduce these structures, coevolutionary modeling can offer a better understanding of the underlying dynamics. This paper presents an overview of recent work on coevolutionary models of network formation, with an emphasis on the following three settings: (i) dynamic flow of benefits and costs, (ii) transient link establishment costs, and (iii) latent preferential attachment.

  4. Coevolutionary ecological economics

    Energy Technology Data Exchange (ETDEWEB)

    Kallis, Giorgos [ICREA Researcher, ICTA, Universidad Autonoma de Barcelona, ETSE, QC/3095, 08193 Bellatera, Barcelona (Spain); Norgaard, Richard B. [Energy and Resources Group, University of California at Berkeley, 310 Barrows Hall, Berkeley, CA, 94720-3050 (United States)


    This paper maps a coevolutionary research agenda for ecological economics. At an epistemological level coevolution offers a powerful logic for transcending environmental and social determinisms and developing a cross-disciplinary approach in the study of socio-ecological systems. We identify four consistent stories emerging out of coevolutionary studies in ecological economics, concerning: environmental degradation and development failure in peripheral regions; the lock-in of unsustainable production-consumption patterns; the vicious cycle between human efforts to control undesirable micro-organisms and the evolution of these organisms; and the adaptive advantages of other-regarding, cooperative behaviors and institutions. We identify challenges in the conceptualization of coevolutionary relationships in relation to: the interaction between different hierarchical levels of evolution; the role of space and social power; uneven rates of change and crises. We conclude with the political implications of a coevolutionary perspective based on the premises of pragmatism. (author)

  5. Coevolutionary games--a mini review. (United States)

    Perc, Matjaz; Szolnoki, Attila


    Prevalence of cooperation within groups of selfish individuals is puzzling in that it contradicts with the basic premise of natural selection. Favoring players with higher fitness, the latter is key for understanding the challenges faced by cooperators when competing with defectors. Evolutionary game theory provides a competent theoretical framework for addressing the subtleties of cooperation in such situations, which are known as social dilemmas. Recent advances point towards the fact that the evolution of strategies alone may be insufficient to fully exploit the benefits offered by cooperative behavior. Indeed, while spatial structure and heterogeneity, for example, have been recognized as potent promoters of cooperation, coevolutionary rules can extend the potentials of such entities further, and even more importantly, lead to the understanding of their emergence. The introduction of coevolutionary rules to evolutionary games implies, that besides the evolution of strategies, another property may simultaneously be subject to evolution as well. Coevolutionary rules may affect the interaction network, the reproduction capability of players, their reputation, mobility or age. Here we review recent works on evolutionary games incorporating coevolutionary rules, as well as give a didactic description of potential pitfalls and misconceptions associated with the subject. In addition, we briefly outline directions for future research that we feel are promising, thereby particularly focusing on dynamical effects of coevolutionary rules on the evolution of cooperation, which are still widely open to research and thus hold promise of exciting new discoveries. Copyright (c) 2009 Elsevier Ireland Ltd. All rights reserved.

  6. Coevolutionary aesthetics in human and biotic artworlds. (United States)

    Prum, Richard O


    This work proposes a coevolutionary theory of aesthetics that encompasses both biotic and human arts. Anthropocentric perspectives in aesthetics prevent the recognition of the ontological complexity of the aesthetics of nature, and the aesthetic agency of many non-human organisms. The process of evaluative coevolution is shared by all biotic advertisements. I propose that art consists of a form of communication that coevolves with its own evaluation. Art and art history are population phenomena. I expand Arthur Danto's Artworld concept to any aesthetic population of producers and evaluators. Current concepts of art cannot exclusively circumscribe the human arts from many forms of non-human biotic art. Without assuming an arbitrarily anthropocentric perspective, any concept of art will need to engage with biodiversity, and either recognize many instances of biotic advertisements as art, or exclude some instances of human art. Coevolutionary aesthetic theory provides a heuristic account of aesthetic change in both human and biotic artworlds, including the coevolutionary origin of aesthetic properties and aesthetic value within artworlds. Restructuring aesthetics, art criticism, and art history without human beings at the organizing centers of these disciplines stimulate new progress in our understanding of art, and the unique human contributions to aesthetics and aesthetic diversity.

  7. Phages of lactic acid bacteria: The role of genetics in understanding phage-host interactions and their co-evolutionary processes

    International Nuclear Information System (INIS)

    Mahony, Jennifer; Ainsworth, Stuart; Stockdale, Stephen; Sinderen, Douwe van


    Dairy fermentations are among the oldest food processing applications, aimed at preservation and shelf-life extension through the use of lactic acid bacteria (LAB) starter cultures, in particular strains of Lactococcus lactis, Streptococcus thermophilus, Lactobacillus spp. and Leuconostoc spp. Traditionally this was performed by continuous passaging of undefined cultures from a finished fermentation to initiate the next fermentation. More recently, consumer demands on consistent and desired flavours and textures of dairy products have led to a more defined approach to such processes. Dairy (starter) companies have responded to the need to define the nature and complexity of the starter culture mixes, and dairy fermentations are now frequently based on defined starter cultures of low complexity, where each starter component imparts specific technological properties that are desirable to the product. Both mixed and defined starter culture approaches create the perfect environment for the proliferation of (bacterio)phages capable of infecting these LAB. The repeated use of the same starter cultures in a single plant, coupled to the drive towards higher and consistent production levels, increases the risk and negative impact of phage infection. In this review we will discuss recent advances in tracking the adaptation of phages to the dairy industry, the advances in understanding LAB phage-host interactions, including evolutionary and genomic aspects.

  8. Phages of lactic acid bacteria: The role of genetics in understanding phage-host interactions and their co-evolutionary processes

    Energy Technology Data Exchange (ETDEWEB)

    Mahony, Jennifer, E-mail: [Department of Microbiology, University College Cork, Western Road, Cork (Ireland); Ainsworth, Stuart; Stockdale, Stephen [Department of Microbiology, University College Cork, Western Road, Cork (Ireland); Sinderen, Douwe van, E-mail: [Department of Microbiology, University College Cork, Western Road, Cork (Ireland); Alimentary Pharmabiotic Centre, Biosciences Institute, University College Cork, Western Road, Cork (Ireland)


    Dairy fermentations are among the oldest food processing applications, aimed at preservation and shelf-life extension through the use of lactic acid bacteria (LAB) starter cultures, in particular strains of Lactococcus lactis, Streptococcus thermophilus, Lactobacillus spp. and Leuconostoc spp. Traditionally this was performed by continuous passaging of undefined cultures from a finished fermentation to initiate the next fermentation. More recently, consumer demands on consistent and desired flavours and textures of dairy products have led to a more defined approach to such processes. Dairy (starter) companies have responded to the need to define the nature and complexity of the starter culture mixes, and dairy fermentations are now frequently based on defined starter cultures of low complexity, where each starter component imparts specific technological properties that are desirable to the product. Both mixed and defined starter culture approaches create the perfect environment for the proliferation of (bacterio)phages capable of infecting these LAB. The repeated use of the same starter cultures in a single plant, coupled to the drive towards higher and consistent production levels, increases the risk and negative impact of phage infection. In this review we will discuss recent advances in tracking the adaptation of phages to the dairy industry, the advances in understanding LAB phage-host interactions, including evolutionary and genomic aspects.

  9. Joint coevolutionary-epidemiological models dampen Red Queen cycles and alter conditions for epidemics. (United States)

    MacPherson, Ailene; Otto, Sarah P


    Host-parasite interactions in the form of infectious diseases are a topic of interest in both evolutionary biology and public health. Both fields have relied on mathematical models to predict and understand the dynamics and consequences of these interactions. Yet few models explicitly incorporate both epidemiological and coevolutionary dynamics, allowing for genetic variation in both hosts and parasites. By comparing a matching-alleles model of coevolution, a susceptible-infected-recovered-susceptible compartmental model from epidemiology, and a combined coevolutionary-epidemiology model we assess the effect of the coevolutionary feedback on the epidemiological dynamics and vice versa. We find that Red-Queen cycles are not robust in an epidemiological framework and that coevolutionary interactions can alter the conditions under which epidemic cycles arise. Incorporating both explicit epidemiology and genetic diversity may have important implications for the maintenance of sexual reproduction as well as disease management. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. Understanding of the sources of the F-region field-aligned irregularities in the middle latitude using ground-based and satellite observations (United States)

    Kwak, Y. S.; Kil, H.; Yang, T. Y.; Park, J.; Choi, J. M.


    The electron density irregularities in the F region are problematic in satellite communication and navigation systems. Extensive efforts have been made to understand the onset conditions and sources of such irregularities and to predict or avoid the impact of these irregularities on the society. A VHF radar was built at Daejeon (36.2°N, 127.1°E, 26.7°N dip latitude) in South Korea in December 2009 to study the characteristics and source of the irregularities in middle latitudes. Our study investigates the occurrence climatology of the field-aligned irregularities (FAIs) and their association with medium-scale traveling ionospheric disturbances (MSTIDs) and sporadic E. The activity of FAIs is investigated with the Daejeon radar data acquired in 2010-2016, and the occurrences of MSTIDs and sporadic E are monitored with the total electron content maps over Japan and ionosonde data at Icheon in South Korea, respectively. Swarm satellite observations are used to investigate the field-aligned properties in the F-region FAIs. Through the comparison of the activities of F-region FAIs, MSTIDs, and sporadic E, we assess the role of MSTIDs and sporadic E in the creation of the F-region FAIs.

  11. Robust Traffic Flow Management: Coevolutionary Approach, Phase I (United States)

    National Aeronautics and Space Administration — We will develop a Coevolutionary Decision Support Tool (CDST) that explicitly incorporates weather uncertainty (non-probabilistically) into strategic Traffic Flow...

  12. Irregular Periods (United States)

    ... is not regular, you'll want to pay attention to the clues your body may give you. These may include: back cramps or stiffness heavier breasts or breast soreness headaches acne breakouts disturbed sleep patterns mood swings bloating Most of the time, irregular ...

  13. Public goods games on adaptive coevolutionary networks (United States)

    Pichler, Elgar; Shapiro, Avi M.


    Productive societies feature high levels of cooperation and strong connections between individuals. Public Goods Games (PGGs) are frequently used to study the development of social connections and cooperative behavior in model societies. In such games, contributions to the public good are made only by cooperators, while all players, including defectors, reap public goods benefits, which are shares of the contributions amplified by a synergy factor. Classic results of game theory show that mutual defection, as opposed to cooperation, is the Nash Equilibrium of PGGs in well-mixed populations, where each player interacts with all others. In this paper, we explore the coevolutionary dynamics of a low information public goods game on a complex network in which players adapt to their environment in order to increase individual payoffs relative to past payoffs parameterized by greediness. Players adapt by changing their strategies, either to cooperate or to defect, and by altering their social connections. We find that even if players do not know other players' strategies and connectivity, cooperation can arise and persist despite large short-term fluctuations.

  14. Irregular amalgams

    Directory of Open Access Journals (Sweden)

    James Stewart


    Full Text Available The amalgam of Lp and ℓq consists of those functions for which the sequence of Lp-norms over the intervals [n,n+1 is in ℓq. These spaces (Lp,ℓq have been studied in several recent papers. Here we replace the intervals [n,n+1 by a cover α={In;n∈Z} of the real line consisting of disjoint half-open intervals In each of the form [a,b, and investigate which properties of (Lp,ℓq carry over to these irregular amalgams (Lp,ℓqα. In particular, we study how (Lp,ℓqα varies as p, q, and α vary and determine conditions under which translation is continuous.

  15. A Coevolutionary Arms Race: Understanding Plant-Herbivore Interactions (United States)

    Becklin, Katie M.


    Plants and insects share a long evolutionary history characterized by relationships that affect individual, population, and community dynamics. Plant-herbivore interactions are a prominent feature of this evolutionary history; it is by plant-herbivore interactions that energy is transferred from primary producers to the rest of the food web. Not…

  16. Irregular migration: an international perspective. (United States)

    Tomasi, S M


    Despite the heightened awareness of irregular migrations worldwide, a certain misappreciation or underestimation of the saliency of irregular migration issues persists. Conflict in the strife-torn Indian state of Assam, for example, has been widely publicized, but its roots in immigration issues linked to communal tensions are insufficiently understood. Conflict around the globe seems increasingly to involve, both as cause and effect, migrants in irregular status whose problematical or illegitimate presence itself is at issue. The global recession prompted governments in immigration-welcoming countries to adopt more restrictive stances vis-a-vis immigration at a time when global migratory pressures were expanding enormously. As if by a process of demonstration effect, 1 country after another began to view migratory flows with alarm--flows which previously had been regarded as benign or quantitatively unimportant. Part I of this special issue examines a variety of public responses to irregular migration. Part II looks at legalization issues in a number of national contexts. Part III contains 3 comparative reflections on immigration reform in industrial democracies. Part IV provides an overview and sampling of recent empirical and survey research findings on irregular status migrants, primarily in the US. This special issue is intended to encourage further research on irregular migration, foster better understanding of this complex phenomenon, and contribute to enlightened public policy-making.

  17. What Causes Menstrual Irregularities? (United States)

    ... Share Facebook Twitter Pinterest Email Print What causes menstrual irregularities? Menstrual irregularities can have a variety of ... health problems Common causes of heavy or prolonged menstrual bleeding include: 2 , 7 Adolescence (during which cycles ...

  18. Cyber Security Research Frameworks For Coevolutionary Network Defense

    Energy Technology Data Exchange (ETDEWEB)

    Rush, George D. [Missouri Univ. of Science and Technology, Rolla, MO (United States); Tauritz, Daniel Remy [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)


    Several architectures have been created for developing and testing systems used in network security, but most are meant to provide a platform for running cyber security experiments as opposed to automating experiment processes. In the first paper, we propose a framework termed Distributed Cyber Security Automation Framework for Experiments (DCAFE) that enables experiment automation and control in a distributed environment. Predictive analysis of adversaries is another thorny issue in cyber security. Game theory can be used to mathematically analyze adversary models, but its scalability limitations restrict its use. Computational game theory allows us to scale classical game theory to larger, more complex systems. In the second paper, we propose a framework termed Coevolutionary Agent-based Network Defense Lightweight Event System (CANDLES) that can coevolve attacker and defender agent strategies and capabilities and evaluate potential solutions with a custom network defense simulation. The third paper is a continuation of the CANDLES project in which we rewrote key parts of the framework. Attackers and defenders have been redesigned to evolve pure strategy, and a new network security simulation is devised which specifies network architecture and adds a temporal aspect. We also add a hill climber algorithm to evaluate the search space and justify the use of a coevolutionary algorithm.

  19. A Cooperative Coevolutionary Cuckoo Search Algorithm for Optimization Problem

    Directory of Open Access Journals (Sweden)

    Hongqing Zheng


    Full Text Available Taking inspiration from an organizational evolutionary algorithm for numerical optimization, this paper designs a kind of dynamic population and combining evolutionary operators to form a novel algorithm, a cooperative coevolutionary cuckoo search algorithm (CCCS, for solving both unconstrained, constrained optimization and engineering problems. A population of this algorithm consists of organizations, and an organization consists of dynamic individuals. In experiments, fifteen unconstrained functions, eleven constrained functions, and two engineering design problems are used to validate the performance of CCCS, and thorough comparisons are made between the CCCS and the existing approaches. The results show that the CCCS obtains good performance in the solution quality. Moreover, for the constrained problems, the good performance is obtained by only incorporating a simple constraint handling technique into the CCCS. The results show that the CCCS is quite robust and easy to use.

  20. Using of coevolutionary algorithm on P2P networks

    Directory of Open Access Journals (Sweden)

    Rezaee Alireza


    Full Text Available Multicast routing is the basic demand to provide QOS (Quality of service in multimedia streaming on peer to peer networks. Making multicast trees optimizing their delay cost and considering nodal and links limited bandwidth (load balance constraints is a NP-hard (Nondeterministic Polynomial time hard problem. In this paper we have used Co-evolutionary Algorithm to make multicast trees with optimized average delay from source to the clients considering the limited capacity of nodes and links in application layer. The numeric results obtained are shown that the costs have been much improved comparing with other existent non-GA (Genetic Algorithm approaches. Also we have used only a portion of every nodal outage degree and this has improved the results comparing to use of the entire outage degree.

  1. What Are Menstrual Irregularities? (United States)

    ... NICHD Research Information Find a Study More Information Amenorrhea About NICHD Research Information Find a Study More ... not occur. The most common menstrual irregularities include: Amenorrhea (pronounced ey-men-uh-REE-uh ) or absent ...

  2. Irregular sleep-wake syndrome (United States)

    Sleep-wake syndrome - irregular; Circadian rhythm sleep disorder - irregular sleep-wake type ... have sleep disturbances on occasion. But if this type of irregular sleep-wake pattern occurs regularly and without cause, see your provider.

  3. A Case Study of a Multiobjective Elitist Recombinative Genetic Algorithm with Coevolutionary Sharing

    NARCIS (Netherlands)

    Neef, R.M.; Thierens, D.; Arciszewski, H.F.R.


    We present a multiobjective genetic algorithm that incorporates various genetic algorithm techniques that have been proven to be efficient and robust in their problem domain. More specifically, we integrate rank based selection, adaptive niching through coevolutionary sharing, elitist recombination,

  4. A case study of a multiobjective recombinative genetic algorithm with coevolutionary sharing

    NARCIS (Netherlands)

    Neef, R.M.; Thierens, D.; Arciszewski, H.F.R.


    We present a multiobjective genetic algorithm that incorporates various genetic algorithm techniques that have been proven to be efficient and robust in their problem domain. More specifically, we integrate rank based selection, adaptive niching through coevolutionary sharing, elitist recombination,

  5. Perception-based Co-evolutionary Reinforcement Learning for UAV Sensor Allocation

    National Research Council Canada - National Science Library

    Berenji, Hamid


    .... A Perception-based reasoning approach based on co-evolutionary reinforcement learning was developed for jointly addressing sensor allocation on each individual UAV and allocation of a team of UAVs...

  6. Classical Virasoro irregular conformal block (United States)

    Rim, Chaiho; Zhang, Hong


    Virasoro irregular conformal block with arbitrary rank is obtained for the classical limit or equivalently Nekrasov-Shatashvili limit using the beta-deformed irregular matrix model (Penner-type matrix model for the irregular conformal block). The same result is derived using the generalized Mathieu equation which is equivalent to the loop equation of the irregular matrix model.

  7. Classical Virasoro irregular conformal block

    Energy Technology Data Exchange (ETDEWEB)

    Rim, Chaiho; Zhang, Hong [Department of Physics and Center for Quantum Spacetime (CQUeST), Sogang University,Seoul 121-742 (Korea, Republic of)


    Virasoro irregular conformal block with arbitrary rank is obtained for the classical limit or equivalently Nekrasov-Shatashvili limit using the beta-deformed irregular matrix model (Penner-type matrix model for the irregular conformal block). The same result is derived using the generalized Mathieu equation which is equivalent to the loop equation of the irregular matrix model.

  8. A Multipopulation Coevolutionary Strategy for Multiobjective Immune Algorithm

    Directory of Open Access Journals (Sweden)

    Jiao Shi


    Full Text Available How to maintain the population diversity is an important issue in designing a multiobjective evolutionary algorithm. This paper presents an enhanced nondominated neighbor-based immune algorithm in which a multipopulation coevolutionary strategy is introduced for improving the population diversity. In the proposed algorithm, subpopulations evolve independently; thus the unique characteristics of each subpopulation can be effectively maintained, and the diversity of the entire population is effectively increased. Besides, the dynamic information of multiple subpopulations is obtained with the help of the designed cooperation operator which reflects a mutually beneficial relationship among subpopulations. Subpopulations gain the opportunity to exchange information, thereby expanding the search range of the entire population. Subpopulations make use of the reference experience from each other, thereby improving the efficiency of evolutionary search. Compared with several state-of-the-art multiobjective evolutionary algorithms on well-known and frequently used multiobjective and many-objective problems, the proposed algorithm achieves comparable results in terms of convergence, diversity metrics, and running time on most test problems.

  9. Molecular evolution of rbcL in three gymnosperm families: identifying adaptive and coevolutionary patterns

    Directory of Open Access Journals (Sweden)

    Gao Lei


    Full Text Available Abstract Background The chloroplast-localized ribulose-1, 5-biphosphate carboxylase/oxygenase (Rubisco, the primary enzyme responsible for autotrophy, is instrumental in the continual adaptation of plants to variations in the concentrations of CO2. The large subunit (LSU of Rubisco is encoded by the chloroplast rbcL gene. Although adaptive processes have been previously identified at this gene, characterizing the relationships between the mutational dynamics at the protein level may yield clues on the biological meaning of such adaptive processes. The role of such coevolutionary dynamics in the continual fine-tuning of RbcL remains obscure. Results We used the timescale and phylogenetic analyses to investigate and search for processes of adaptive evolution in rbcL gene in three gymnosperm families, namely Podocarpaceae, Taxaceae and Cephalotaxaceae. To understand the relationships between regions identified as having evolved under adaptive evolution, we performed coevolutionary analyses using the software CAPS. Importantly, adaptive processes were identified at amino acid sites located on the contact regions among the Rubisco subunits and on the interface between Rubisco and its activase. Adaptive amino acid replacements at these regions may have optimized the holoenzyme activity. This hypothesis was pinpointed by evidence originated from our analysis of coevolution that supported the correlated evolution between Rubisco and its activase. Interestingly, the correlated adaptive processes between both these proteins have paralleled the geological variation history of the concentration of atmospheric CO2. Conclusions The gene rbcL has experienced bursts of adaptations in response to the changing concentration of CO2 in the atmosphere. These adaptations have emerged as a result of a continuous dynamic of mutations, many of which may have involved innovation of functional Rubisco features. Analysis of the protein structure and the functional

  10. Molecular evolution of rbcL in three gymnosperm families: identifying adaptive and coevolutionary patterns. (United States)

    Sen, Lin; Fares, Mario A; Liang, Bo; Gao, Lei; Wang, Bo; Wang, Ting; Su, Ying-Juan


    The chloroplast-localized ribulose-1, 5-biphosphate carboxylase/oxygenase (Rubisco), the primary enzyme responsible for autotrophy, is instrumental in the continual adaptation of plants to variations in the concentrations of CO2. The large subunit (LSU) of Rubisco is encoded by the chloroplast rbcL gene. Although adaptive processes have been previously identified at this gene, characterizing the relationships between the mutational dynamics at the protein level may yield clues on the biological meaning of such adaptive processes. The role of such coevolutionary dynamics in the continual fine-tuning of RbcL remains obscure. We used the timescale and phylogenetic analyses to investigate and search for processes of adaptive evolution in rbcL gene in three gymnosperm families, namely Podocarpaceae, Taxaceae and Cephalotaxaceae. To understand the relationships between regions identified as having evolved under adaptive evolution, we performed coevolutionary analyses using the software CAPS. Importantly, adaptive processes were identified at amino acid sites located on the contact regions among the Rubisco subunits and on the interface between Rubisco and its activase. Adaptive amino acid replacements at these regions may have optimized the holoenzyme activity. This hypothesis was pinpointed by evidence originated from our analysis of coevolution that supported the correlated evolution between Rubisco and its activase. Interestingly, the correlated adaptive processes between both these proteins have paralleled the geological variation history of the concentration of atmospheric CO2. The gene rbcL has experienced bursts of adaptations in response to the changing concentration of CO2 in the atmosphere. These adaptations have emerged as a result of a continuous dynamic of mutations, many of which may have involved innovation of functional Rubisco features. Analysis of the protein structure and the functional implications of such mutations put forward the conclusion that

  11. Molecular evolution of rbcL in three gymnosperm families: identifying adaptive and coevolutionary patterns

    LENUS (Irish Health Repository)

    Sen, Lin


    Abstract Background The chloroplast-localized ribulose-1, 5-biphosphate carboxylase\\/oxygenase (Rubisco), the primary enzyme responsible for autotrophy, is instrumental in the continual adaptation of plants to variations in the concentrations of CO2. The large subunit (LSU) of Rubisco is encoded by the chloroplast rbcL gene. Although adaptive processes have been previously identified at this gene, characterizing the relationships between the mutational dynamics at the protein level may yield clues on the biological meaning of such adaptive processes. The role of such coevolutionary dynamics in the continual fine-tuning of RbcL remains obscure. Results We used the timescale and phylogenetic analyses to investigate and search for processes of adaptive evolution in rbcL gene in three gymnosperm families, namely Podocarpaceae, Taxaceae and Cephalotaxaceae. To understand the relationships between regions identified as having evolved under adaptive evolution, we performed coevolutionary analyses using the software CAPS. Importantly, adaptive processes were identified at amino acid sites located on the contact regions among the Rubisco subunits and on the interface between Rubisco and its activase. Adaptive amino acid replacements at these regions may have optimized the holoenzyme activity. This hypothesis was pinpointed by evidence originated from our analysis of coevolution that supported the correlated evolution between Rubisco and its activase. Interestingly, the correlated adaptive processes between both these proteins have paralleled the geological variation history of the concentration of atmospheric CO2. Conclusions The gene rbcL has experienced bursts of adaptations in response to the changing concentration of CO2 in the atmosphere. These adaptations have emerged as a result of a continuous dynamic of mutations, many of which may have involved innovation of functional Rubisco features. Analysis of the protein structure and the functional implications of such

  12. Cry-wolf signals emerging from coevolutionary feedbacks in a tritrophic system (United States)

    Yamauchi, Atsushi; van Baalen, Minus; Kobayashi, Yutaka; Takabayashi, Junji; Shiojiri, Kaori; Sabelis, Maurice W.


    For a communication system to be stable, senders should convey honest information. Providing dishonest information, however, can be advantageous to senders, which imposes a constraint on the evolution of communication systems. Beyond single populations and bitrophic systems, one may ask whether stable communication systems can evolve in multitrophic systems. Consider cross-species signalling where herbivore-induced plant volatiles (HIPVs) attract predators to reduce the damage from arthropod herbivores. Such plant signals may be honest and help predators to identify profitable prey/plant types via HIPV composition and to assess prey density via the amount of HIPVs. There could be selection for dishonest signals that attract predators for protection from possible future herbivory. Recently, we described a case in which plants release a fixed, high amount of HIPVs independent of herbivore load, adopting what we labelled a ‘cry-wolf’ strategy. To understand when such signals evolve, we model coevolutionary interactions between plants, herbivores and predators, and show that both ‘honest’ and ‘cry-wolf’ types can emerge, depending on the assumed plant–herbivore encounter rates and herbivore population density. It is suggested that the ‘cry-wolf’ strategy may have evolved to reduce the risk of heavy damage in the future. Our model suggests that eco-evolutionary feedback loops involving a third species may have important consequences for the stability of this outcome. PMID:26538597

  13. Understanding the Unique Equatorial Density Irregularities (United States)


    are shown in Figure 9. The results show the comparison of the total solar irradiance ( TSI ) output from neural networks after data assimilation (green...line) TSI . 10 Distribution A: Approved for public release; distribution is unlimited.

  14. Understanding the sensory irregularities of esophageal disease. (United States)

    Farmer, Adam D; Brock, Christina; Frøkjaer, Jens Brøndum; Gregersen, Hans; Khan, Sheeba; Lelic, Dina; Lottrup, Christian; Drewes, Asbjørn Mohr


    Symptoms relating to esophageal sensory abnormalities can be encountered in the clinical environment. Such sensory abnormalities may be present in demonstrable disease, such as erosive esophagitis, and in the ostensibly normal esophagus, such as non-erosive reflux disease or functional chest pain. In this review, the authors discuss esophageal sensation and the esophageal pain system. In addition, the authors provide a primer concerning the techniques that are available for investigating the autonomic nervous system, neuroimaging and neurophysiology of esophageal sensory function. Such technological advances, whilst not readily available in the clinic may facilitate the stratification and individualization of therapy in disorders of esophageal sensation in the future.

  15. Saturn's Irregular Moon Ymir (United States)

    Denk, Tilmann; Mottola, S.


    Ymir (diameter 18 km), Saturn's second largest retrograde outer or irregular moon, has been observed six times by the Cassini narrow-angle camera (NAC) during the first 7 months in 2012. The observations span phase angles from 2° up to 102° and were taken at ranges between 15 and 18 million kilometers. From such a distance, Ymir is smaller than a pixel in the Cassini NAC. The data reveal a sidereal rotation period of 11.93 hrs, which is 1.6x longer than the previously reported value (Denk et al. 2011, EPSC/DPS #1452). Reason for this discrepancy is that the rotational light curve shows a rather uncommon 3-maxima and 3-minima shape at least in the phase angle range 50° to 100°, which was not recognizable in earlier data. The data cover several rotations from different viewing and illumination geometries and allow for a convex shape inversion with possibly a unique solution for the pole direction. The model reproduces the observed light curves to a very good accuracy without requiring albedo variegation, thereby suggesting that the lightcurve is dominated by the shape of Ymir. Among Saturn's irregular moons, the phenomenon of more than two maxima and minima at moderate to high phase angles is not unique to Ymir. At least Siarnaq and Paaliaq also show light curves with a strong deviation from a double-sine curve. Their rotation periods, however, remain unknown until more data can be taken. The light curve of Phoebe is fundamentally different to Ymir's because it is mainly shaped by local albedo differences and not by shape. Other reliable rotation periods of irregular satellites measured by Cassini include: Mundilfari 6.74 h; Kari 7.70 h; Albiorix 13.32 h; Kiviuq 21.82 h. More uncertain values are: Skathi 12 h; Bebhionn 16 h; Thrymr 27 h; Erriapus 28 h.

  16. Characteristics and sources of the electron density irregularities in the mid latitude E and Fregions (United States)


    such irregularities, to understand the onset conditions of such irregularities, and to predict or avoid the impact of these irregularities on society ...impact of these irregularities on society . Such electron density irregularities in the ionosphere exhibit an anisotropic distribution with respect to...with QP echoes, mapped upward along the geomagnetic field, and played an important role in determining the structures of the whole ionospheric E region

  17. Species co-evolutionary algorithm: a novel evolutionary algorithm based on the ecology and environments for optimization

    DEFF Research Database (Denmark)

    Li, Wuzhao; Wang, Lei; Cai, Xingjuan


    and affect each other in many ways. The relationships include competition, predation, parasitism, mutualism and pythogenesis. In this paper, we consider the five relationships between solutions to propose a co-evolutionary algorithm termed species co-evolutionary algorithm (SCEA). In SCEA, five operators...

  18. Parasitic castration promotes coevolutionary cycling but also imposes a cost on sex. (United States)

    Ashby, Ben; Gupta, Sunetra


    Antagonistic coevolution between hosts and parasites is thought to drive a range of biological phenomena including the maintenance of sexual reproduction. Of particular interest are conditions that produce persistent fluctuations in the frequencies of genes governing host-parasite specificity (coevolutionary cycling), as sex may be more beneficial than asexual reproduction in a constantly changing environment. Although many studies have shown that coevolutionary cycling can lead to the maintenance of sex, the effects of ecological feedbacks on the persistence of these fluctuations in gene frequencies are not well understood. Here, we use a simple deterministic model that incorporates ecological feedbacks to explore how parasitic reductions in host fecundity affect the maintenance of coevolutionary cycling. We demonstrate that parasitic castration is inherently destabilizing and may be necessary for coevolutionary cycling to persist indefinitely, but also reduces the likelihood that sexually reproducing individuals will find a fertile partner, which may select against sex. These findings suggest that castrators can play an important role in shaping host evolution and are likely to be good targets for observing fluctuations in gene frequencies that govern specificity in host-parasite interactions. © 2014 The Author(s). Evolution © 2014 The Society for the Study of Evolution.

  19. The bitterling–mussel coevolutionary relationship in areas of recent and ancient sympatry

    Czech Academy of Sciences Publication Activity Database

    Reichard, Martin; Polačik, Matej; Tarkan, A. S.; Spence, R.; Gaygusuz, Ö.; Ercan, E.; Ondračková, Markéta; Smith, C.


    Roč. 64, č. 10 (2010), s. 3047-3056 ISSN 0014-3820 R&D Projects: GA AV ČR KJB600930802 Institutional research plan: CEZ:AV0Z60930519 Keywords : coevolutionary arm races * evolutionary lag * gentes * host race * specialization * symbiosis Subject RIV: EG - Zoology Impact factor: 5.659, year: 2010

  20. Phylogeny of diving beetles reveals a coevolutionary arms race between the sexes.

    Directory of Open Access Journals (Sweden)

    Johannes Bergsten

    Full Text Available BACKGROUND: Darwin illustrated his sexual selection theory with male and female morphology of diving beetles, but maintained a cooperative view of their interaction. Present theory suggests that instead sexual conflict should be a widespread evolutionary force driving both intersexual coevolutionary arms races and speciation. METHODOLOGY/PRINCIPAL FINDINGS: We combined Bayesian phylogenetics, complete taxon sampling and a multi-gene approach to test the arms race scenario on a robust diving beetle phylogeny. As predicted, suction cups in males and modified dorsal surfaces in females showed a pronounced coevolutionary pattern. The female dorsal modifications impair the attachment ability of male suction cups, but each antagonistic novelty in females corresponds to counter-differentiation of suction cups in males. CONCLUSIONS: A recently diverged sibling species pair in Japan is possibly one consequence of this arms race and we suggest that future studies on hypoxia might reveal the key to the extraordinary selection for female counter-adaptations in diving beetles.

  1. Transdisciplinary Perspectives in Bioethics: A Co-evolutionary Introduction from the Big History

    Directory of Open Access Journals (Sweden)

    Javier Collado-Ruano


    Full Text Available The main objective of this work is to expand the bioethics notion expressed in the Article 17th of the Universal Declaration on Bioethics and Human Rights, concerning the interconnections between human beings and other life forms. For this purpose, it is combined the transdisciplinary methodology with the theoretical framework of the “Big History” to approach the co-evolutionary phenomena that life is developing on Earth for some 3.8 billion years. As a result, the study introduces us to the unification, integration and inclusion of the history of the universe, the solar system, Earth, and life with the history of human beings. In conclusion, I consider to safeguard the cosmic miracle that represents the emergence of life we must adopt new transdisciplinary perspectives into bioethics to address the ecosystem complexity of co-evolutionary processes of life on Gaia as a whole.

  2. Coevolutionary particle swarm optimization using Gaussian distribution for solving constrained optimization problems. (United States)

    Krohling, Renato A; Coelho, Leandro dos Santos


    In this correspondence, an approach based on coevolutionary particle swarm optimization to solve constrained optimization problems formulated as min-max problems is presented. In standard or canonical particle swarm optimization (PSO), a uniform probability distribution is used to generate random numbers for the accelerating coefficients of the local and global terms. We propose a Gaussian probability distribution to generate the accelerating coefficients of PSO. Two populations of PSO using Gaussian distribution are used on the optimization algorithm that is tested on a suite of well-known benchmark constrained optimization problems. Results have been compared with the canonical PSO (constriction factor) and with a coevolutionary genetic algorithm. Simulation results show the suitability of the proposed algorithm in terms of effectiveness and robustness.

  3. Multi-step-prediction of chaotic time series based on co-evolutionary recurrent neural network

    International Nuclear Information System (INIS)

    Ma Qianli; Zheng Qilun; Peng Hong; Qin Jiangwei; Zhong Tanwei


    This paper proposes a co-evolutionary recurrent neural network (CERNN) for the multi-step-prediction of chaotic time series, it estimates the proper parameters of phase space reconstruction and optimizes the structure of recurrent neural networks by co-evolutionary strategy. The searching space was separated into two subspaces and the individuals are trained in a parallel computational procedure. It can dynamically combine the embedding method with the capability of recurrent neural network to incorporate past experience due to internal recurrence. The effectiveness of CERNN is evaluated by using three benchmark chaotic time series data sets: the Lorenz series, Mackey-Glass series and real-world sun spot series. The simulation results show that CERNN improves the performances of multi-step-prediction of chaotic time series

  4. Network intrusion detection by the coevolutionary immune algorithm of artificial immune systems with clonal selection (United States)

    Salamatova, T.; Zhukov, V.


    The paper presents the application of the artificial immune systems apparatus as a heuristic method of network intrusion detection for algorithmic provision of intrusion detection systems. The coevolutionary immune algorithm of artificial immune systems with clonal selection was elaborated. In testing different datasets the empirical results of evaluation of the algorithm effectiveness were achieved. To identify the degree of efficiency the algorithm was compared with analogs. The fundamental rules based of solutions generated by this algorithm are described in the article.

  5. Irregular Dwarf Galaxy IC 1613 (United States)


    Ultraviolet image (left) and visual image (right) of the irregular dwarf galaxy IC 1613. Low surface brightness galaxies, such as IC 1613, are more easily detected in the ultraviolet because of the low background levels compared to visual wavelengths.

  6. Coevolutionary modeling of protein sequences: Predicting structure, function, and mutational landscapes (United States)

    Weigt, Martin

    Over the last years, biological research has been revolutionized by experimental high-throughput techniques, in particular by next-generation sequencing technology. Unprecedented amounts of data are accumulating, and there is a growing request for computational methods unveiling the information hidden in raw data, thereby increasing our understanding of complex biological systems. Statistical-physics models based on the maximum-entropy principle have, in the last few years, played an important role in this context. To give a specific example, proteins and many non-coding RNA show a remarkable degree of structural and functional conservation in the course of evolution, despite a large variability in amino acid sequences. We have developed a statistical-mechanics inspired inference approach - called Direct-Coupling Analysis - to link this sequence variability (easy to observe in sequence alignments, which are available in public sequence databases) to bio-molecular structure and function. In my presentation I will show, how this methodology can be used (i) to infer contacts between residues and thus to guide tertiary and quaternary protein structure prediction and RNA structure prediction, (ii) to discriminate interacting from non-interacting protein families, and thus to infer conserved protein-protein interaction networks, and (iii) to reconstruct mutational landscapes and thus to predict the phenotypic effect of mutations. References [1] M. Figliuzzi, H. Jacquier, A. Schug, O. Tenaillon and M. Weigt ''Coevolutionary landscape inference and the context-dependence of mutations in beta-lactamase TEM-1'', Mol. Biol. Evol. (2015), doi: 10.1093/molbev/msv211 [2] E. De Leonardis, B. Lutz, S. Ratz, S. Cocco, R. Monasson, A. Schug, M. Weigt ''Direct-Coupling Analysis of nucleotide coevolution facilitates RNA secondary and tertiary structure prediction'', Nucleic Acids Research (2015), doi: 10.1093/nar/gkv932 [3] F. Morcos, A. Pagnani, B. Lunt, A. Bertolino, D. Marks, C

  7. Cartography of irregularly shaped satellites (United States)

    Batson, R. M.; Edwards, Kathleen


    Irregularly shaped satellites, such as Phobos and Amalthea, do not lend themselves to mapping by conventional methods because mathematical projections of their surfaces fail to convey an accurate visual impression of the landforms, and because large and irregular scale changes make their features difficult to measure on maps. A digital mapping technique has therefore been developed by which maps are compiled from digital topographic and spacecraft image files. The digital file is geometrically transformed as desired for human viewing, either on video screens or on hard copy. Digital files of this kind consist of digital images superimposed on another digital file representing the three-dimensional form of a body.

  8. Analysis of irregularly distributed points

    DEFF Research Database (Denmark)

    Hartelius, Karsten


    , but the usage of simple kriging may lead to ill-conditioned matrices when applied to highly irregularly distributed points. Adaptive Kalman filter schemes are investigated. A new parallel Kalman filter algorithm based on windowing technique gives good results in a case study on the Igallico satellite scene...... and represents an interesting contextuel classifier. Extended Kalman filtering on the other hand seems to be well suited for interpolation in gradually changing environments. Bayesian restoration is applied to a point matching problem, which consists of matching a grid to an image of (irregularly) distributed...

  9. An inverse voter model for co-evolutionary networks: Stationary efficiency and phase transitions

    International Nuclear Information System (INIS)

    Zhu Chenping; Kong Hui; Li Li; Gu Zhiming; Xiong Shijie


    In some co-evolutionary networks, the nodes always flip their states between two opposite ones, changing the types of the links to others correspondingly. Meanwhile, the link-rewiring and state-flipping processes feed back each other, and only the links between the nodes in the opposite states are productive in generating flow for the network. We propose an inverse voter model to depict the basic features of them. New phase transitions from full efficiency to deficiency state are found by both the analysis and simulations starting from the random graphs and small-world networks. We suggest a new way to measure the efficiency of networks.

  10. Optimization of DP-M-QAM Transmitter using Cooperative Coevolutionary Genetic Algorithm

    DEFF Research Database (Denmark)

    Medeiros Diniz, Júlio César; Da Ros, Francesco; Porto da Silva, Edson


    We present a method for joint optimization of transmitter in-phase, quadrature and inter-polarization time skew, amplitude mismatch, and bias voltages. The method is based on a cooperative coevolutionary genetic algorithm with fitness functions extracted from a directly detected reference QAM...... signal generated at the transmitter. As a calibration method, it is able to find the values that will statically generate the best possible constellation. To the extent of the simulation investigations conducted, the algorithm is capable to calibrate time skews, bias voltages, IQ phase imbalances...

  11. The Irregular Moons of Saturn (United States)

    Denk, Tilmann; Mottola, Stefano; Tosi, Federico; Bottke, William; Hamilton, Douglas P.


    The 38 irregular moons of Saturn, all but Phoebe discovered between 2000 and 2007, outnumber the planet's classical satellites. Observations from the ground and from near-Earth space have revealed orbits, sizes, and colors and have hinted at the existence of dynamical families, indicative of collisional evolution and common progenitors. More recently, remote observations of many irregular satellites with the Cassini spacecraft produced lightcurves that helped determine rotational periods, coarse shape models, potential hemispheric color heterogeneities, and other basic properties.From Cassini, a total of 25 Saturnian irregulars have been observed with the ISS camera. Their rotational periods range from 5.45 h to 76.13 h. The absence of fast rotators is evident. Among main-belt asteroids of the same size range (~4 to ~45 km), one third of the objects have faster rotations, indicating that many irregulars should be low-density objects.While the origin of the irregulars is still debated, capture of comets via three-body interactions during giant planets encounters does the best job thus far at reproducing the observed prograde/retrograde orbits. Data from the ground, near-Earth spacecraft, and Cassini as well as modeling results suggest the population visible today has experienced substantial collisional evolution. It may be that only Phoebe has survived relatively intact. The small particle debris drifts toward Saturn by P-R drag, with most of it swept up by Titan. Only remnants of this process are visible today.Our current knowledge on the Saturnian irregulars will be summarized in a chapter [1] in the book "Enceladus and the Icy Moons of Saturn" [2]. The talk will give an overview on the chapter's content, which covers the following topics: Orbital "architecture" (a,e,i), sizes and colors, Cassini observations and results, Phoebe, origin, an outlook.[1] Denk, T., Mottola, S., Tosi, F., Bottke, W.F., Hamilton, D.P. (2018): The Irregular Satellites of Saturn. In

  12. Migratory behavior of birds affects their coevolutionary relationship with blood parasites. (United States)

    Jenkins, Tania; Thomas, Gavin H; Hellgren, Olof; Owens, Ian P F


    Host traits, such as migratory behavior, could facilitate the dispersal of disease-causing parasites, potentially leading to the transfer of infections both across geographic areas and between host species. There is, however, little quantitative information on whether variation in such host attributes does indeed affect the evolutionary outcome of host-parasite associations. Here, we employ Leucocytozoon blood parasites of birds, a group of parasites closely related to avian malaria, to study host-parasite coevolution in relation to host behavior using a phylogenetic comparative approach. We reconstruct the molecular phylogenies of both the hosts and parasites and use cophylogenetic tools to assess whether each host-parasite association contributes significantly to the overall congruence between the two phylogenies. We find evidence for a significant fit between host and parasite phylogenies in this system, but show that this is due only to associations between nonmigrant parasites and their hosts. We also show that migrant bird species harbor a greater genetic diversity of parasites compared with nonmigrant species. Taken together, these results suggest that the migratory habits of birds could influence their coevolutionary relationship with their parasites, and that consideration of host traits is important in predicting the outcome of coevolutionary interactions. © 2011 The Author(s). Evolution© 2011 The Society for the Study of Evolution.

  13. The co-evolutionary dynamics of directed network of spin market agents (United States)

    Horváth, Denis; Kuscsik, Zoltán; Gmitra, Martin


    The spin market model [S. Bornholdt, Int. J. Mod. Phys. C 12 (2001) 667] is generalized by employing co-evolutionary principles, where strategies of the interacting and competitive traders are represented by local and global couplings between the nodes of dynamic directed stochastic network. The co-evolutionary principles are applied in the frame of Bak-Sneppen self-organized dynamics [P. Bak, K. Sneppen, Phys. Rev. Lett. 71 (1993) 4083] that includes the processes of selection and extinction actuated by the local (node) fitness. The local fitness is related to orientation of spin agent with respect to the instant magnetization. The stationary regime is formed due to the interplay of self-organization and adaptivity effects. The fat tailed distributions of log-price returns are identified numerically. The non-trivial model consequence is the evidence of the long time market memory indicated by the power-law range of the autocorrelation function of volatility with exponent smaller than one. The simulations yield network topology with broad-scale node degree distribution characterized by the range of exponents 1.3social networks.

  14. An Improved Co-evolutionary Particle Swarm Optimization for Wireless Sensor Networks with Dynamic Deployment

    Directory of Open Access Journals (Sweden)

    Jun-Jie Ma


    Full Text Available The effectiveness of wireless sensor networks (WSNs depends on the coverage and target detection probability provided by dynamic deployment, which is usually supported by the virtual force (VF algorithm. However, in the VF algorithm, the virtual force exerted by stationary sensor nodes will hinder the movement of mobile sensor nodes. Particle swarm optimization (PSO is introduced as another dynamic deployment algorithm, but in this case the computation time required is the big bottleneck. This paper proposes a dynamic deployment algorithm which is named “virtual force directed co-evolutionary particle swarm optimization” (VFCPSO, since this algorithm combines the co-evolutionary particle swarm optimization (CPSO with the VF algorithm, whereby the CPSO uses multiple swarms to optimize different components of the solution vectors for dynamic deployment cooperatively and the velocity of each particle is updated according to not only the historical local and global optimal solutions, but also the virtual forces of sensor nodes. Simulation results demonstrate that the proposed VFCPSO is competent for dynamic deployment in WSNs and has better performance with respect to computation time and effectiveness than the VF, PSO and VFPSO algorithms.

  15. Ionospheric Irregularities at Mars Probed by MARSIS Topside Sounding (United States)

    Harada, Y.; Gurnett, D. A.; Kopf, A. J.; Halekas, J. S.; Ruhunusiri, S.


    The upper ionosphere of Mars contains a variety of perturbations driven by solar wind forcing from above and upward propagating atmospheric waves from below. Here we explore the global distribution and variability of ionospheric irregularities around the exobase at Mars by analyzing topside sounding data from the Mars Advanced Radar for Subsurface and Ionosphere Sounding (MARSIS) instrument on board Mars Express. As irregular structure gives rise to off-vertical echoes with excess propagation time, the diffuseness of ionospheric echo traces can be used as a diagnostic tool for perturbed reflection surfaces. The observed properties of diffuse echoes above unmagnetized regions suggest that ionospheric irregularities with horizontal wavelengths of tens to hundreds of kilometers are particularly enhanced in the winter hemisphere and at high solar zenith angles. Given the known inverse dependence of neutral gravity wave amplitudes on the background atmospheric temperature, the ionospheric irregularities probed by MARSIS are most likely associated with plasma perturbations driven by atmospheric gravity waves. Though extreme events with unusually diffuse echoes are more frequently observed for high solar wind dynamic pressures during some time intervals, the vast majority of the diffuse echo events are unaffected by varying solar wind conditions, implying limited influence of solar wind forcing on the generation of ionospheric irregularities. Combination of remote and in situ measurements of ionospheric irregularities would offer the opportunity for a better understanding of the ionospheric dynamics at Mars.

  16. Co-evolutionary interactions between host resistance and pathogen avirulence genes in rice-Magnaporthe oryzae pathosystem. (United States)

    Singh, Pankaj Kumar; Ray, Soham; Thakur, Shallu; Rathour, Rajeev; Sharma, Vinay; Sharma, Tilak Raj


    Rice and Magnaporthe oryzae constitutes an ideal pathosystem for studying host-pathogen interaction in cereals crops. There are two alternative hypotheses, viz. Arms race and Trench warfare, which explain the co-evolutionary dynamics of hosts and pathogens which are under continuous confrontation. Arms race proposes that both R- and Avr- genes of host and pathogen, respectively, undergo positive selection. Alternatively, trench warfare suggests that either R- or Avr- gene in the pathosystem is under balanced selection intending to stabilize the genetic advantage gained over the opposition. Here, we made an attempt to test the above-stated hypotheses in rice-M. oryzae pathosystem at loci of three R-Avr gene pairs, Piz-t-AvrPiz-t, Pi54-AvrPi54 and Pita-AvrPita using allele mining approach. Allele mining is an efficient way to capture allelic variants existing in the population and to study the selective forces imposed on the variants during evolution. Results of nucleotide diversity, neutrality statistics and phylogenetic analyses reveal that Piz-t, Pi54 and AvrPita are diversified and under positive selection at their corresponding loci, while their counterparts, AvrPiz-t, AvrPi54 and Pita are conserved and under balancing selection, in nature. These results imply that rice-M. oryzae populations are engaged in a trench warfare at least at the three R/Avr loci studied. It is a maiden attempt to study the co-evolution of three R-Avr gene pairs in this pathosystem. Knowledge gained from this study will help in understanding the evolutionary dynamics of host-pathogen interaction in a better way and will also aid in developing new durable blast resistant rice varieties in future. Copyright © 2018 Elsevier Inc. All rights reserved.

  17. Co-Operative Coevolutionary Neural Networks for Mining Functional Association Rules. (United States)

    Wang, Bing; Merrick, Kathryn E; Abbass, Hussein A


    In this paper, we introduce a novel form of association rules (ARs) that do not require discretization of continuous variables or the use of intervals in either sides of the rule. This rule form captures nonlinear relationships among variables, and provides an alternative pattern representation for mining essential relations hidden in a given data set. We refer to the new rule form as a functional AR (FAR). A new neural network-based, co-operative, coevolutionary algorithm is presented for FAR mining. The algorithm is applied to both synthetic and real-world data sets, and its performance is analyzed. The experimental results show that the proposed mining algorithm is able to discover valid and essential underlying relations in the data. Comparison experiments are also carried out with the two state-of-the-art AR mining algorithms that can handle continuous variables to demonstrate the competitive performance of the proposed method.

  18. Co-Evolutionary Algorithm for Motion Planning of Two Industrial Robots with Overlapping Workspaces

    Directory of Open Access Journals (Sweden)

    Petar Curkovic


    Full Text Available A high level of autonomy is a prerequisite for achieving robotic presence in a broad spectrum of work environments. If there is more than one robot in a given environment and the workspaces of robots are shared, then the robots present a dynamic obstacle to each other, which is a potentially dangerous situation. This paper deals with the problem of motion planning for two six-degrees-of-freedom (DOF industrial robots whose workspaces overlap. The planning is based on a novel hall of fame - Pareto-based co-evolutionary algorithm. The modification of the algorithm is directed towards speeding-up co-evolution, to achieve real-time implementation in an industrial robotic system composed of two FANUC LrMate 200iC robots. The results of the simulation and implementation show the great potential of the method in terms of convergence, robustness and time.

  19. The Conundrum of Modern Art : Prestige-Driven Coevolutionary Aesthetics Trumps Evolutionary Aesthetics among Art Experts. (United States)

    Verpooten, Jan; Dewitte, Siegfried


    Two major mechanisms of aesthetic evolution have been suggested. One focuses on naturally selected preferences (Evolutionary Aesthetics), while the other describes a process of evaluative coevolution whereby preferences coevolve with signals. Signaling theory suggests that expertise moderates these mechanisms. In this article we set out to verify this hypothesis in the domain of art and use it to elucidate Western modern art's deviation from naturally selected preferences. We argue that this deviation is consistent with a Coevolutionary Aesthetics mechanism driven by prestige-biased social learning among art experts. In order to test this hypothesis, we conducted two studies in which we assessed the effects on lay and expert appreciation of both the biological relevance of the given artwork's depicted content, viz., facial beauty, and the prestige specific to the artwork's associated context (MoMA). We found that laypeople appreciate artworks based on their depictions of facial beauty, mediated by aesthetic pleasure, which is consistent with previous studies. In contrast, experts appreciate the artworks based on the prestige of the associated context, mediated by admiration for the artist. Moreover, experts appreciate artworks depicting neutral faces to a greater degree than artworks depicting attractive faces. These findings thus corroborate our contention that expertise moderates the Evolutionary and Coevolutionary Aesthetics mechanisms in the art domain. Furthermore, our findings provide initial support for our proposal that prestige-driven coevolution with expert evaluations plays a decisive role in modern art's deviation from naturally selected preferences. After discussing the limitations of our research as well as the relation that our results bear on cultural evolution theory, we provide a number of suggestions for further research into the potential functions of expert appreciation that deviates from naturally selected preferences, on the one hand, and

  20. On m-Neighbourly Irregular Instuitionistic Fuzzy Graphs


    N.R.Santhi Maheswari; C.Sekar


    In this paper, m-neighbourly irregular intuitionistic fuzzy graphs and m- neighbourly totally irregular intuitionistic fuzzy graphs are defined. Relation between m-neighbourly irregular intuitionistic fuzzy graph and m-neighbourly totally irregular intuitionistic fuzzy graph are discussed.

  1. Advanced Stochastic Modeling of Railway Track Irregularities

    Directory of Open Access Journals (Sweden)

    Mengyi Zhu


    Full Text Available As an important interference source of railway vibration, track irregularity is studied in this paper. It is presented that irregularities in the vertical profile and alignment can be modeled as a Gaussian random process. The power spectral density (PSD of the irregularity is calculated and discussed. By analyzing the model, level-crossing properties as well as peak statistics are studied and compared with the observed data.

  2. The total irregularity of a graph

    DEFF Research Database (Denmark)

    Abdo, H.; Brandt, S.; Dimitrov, D.


    In this note a new measure of irregularity of a graph G is introduced. It is named the total irregularity of a graph and is defined as irr(t)(G) - 1/2 Sigma(u, v is an element of V(G)) vertical bar d(G)(u) - d(G)(v)vertical bar, where d(G)(u) denotes the degree of a vertex u is an element of V......(G). All graphs with maximal total irregularity are determined. It is also shown that among all trees of the same order the star has the maximal total irregularity....

  3. The Riddle of a Human Being: A Human Singularity of Co-evolutionary Processes

    Directory of Open Access Journals (Sweden)

    Helena N. Knyazeva


    Full Text Available span style="font-size: 10pt; font-family: #39;Times New Roman#39;"The theory of self-organization of complex systems studies laws of sustainable co-evolutionary development of structures having different speeds of development as well as laws of assembling of a complex evolutionary whole from parts when some elements of ldquo;memoryrdquo; (the biological memory, i.e. DNA, the memory of culture, i.e. the cultural and historical traditions, etc. must be included. The theory reveals general rules of nonlinear synthesis of complex evolutionary structures. The most important and paradoxical consequences of the holistic view, including an approach to solving the riddle of human personality, are as follows: 1 the explanation why and under what conditions a part (a human can be more complex than a whole (society; 2 in order to reconstruct society it is necessary to change an individual but not by cutting off the supposed undesirable past, since a human being as a microcosm is the synthesis of all previous stages of evolution, and as a result of repression of, it would seem, the wild past one can extinguish a ldquo;divine sparkrdquo; in his soul; 3 in the physical sense, singularity denotes a moment of instability, phase transition; one can talk about the human singularity of co-evolutionary processes, since in such a moment of instability individual actions of a human can play a key role in determining a channel of further development as well as in appearance of a new pattern of collective behavior in society; 4 as the models of nonlinear dynamics, elaborated at the Keldysh Institute of Applied Mathematics of the Russian Academy of Sciences in Moscow, show, there is a possibility of a direct influence of the future and even a touch of an infinitely remote future in certain evolutionary regimes and under rigorously definite conditions, more over, it turns out that such a possibility exists only for a human (admittedly, through a specific state of being

  4. Coevolutionary Diversification of Leafflower Moths (Lepidoptera: Gracillariidae: Epicephala) and Leafflower Trees (Phyllanthaceae: Phyllanthus sensu lato [Glochidion]) in Southeastern Polynesia


    Hembry, David Howard


    Coevolution between phylogenetically distant, yet ecologically intimate taxa is widely invoked as a major process generating and organizing biodiversity on earth. Yet for many putatively coevolving clades we lack knowledge both of their evolutionary history of diversification, and the manner in which they organize themselves into patterns of interaction. This is especially true for mutualistic associations, despite the fact that mutualisms have served as models for much coevolutionary resea...

  5. Processing of Irregular Polysemes in Sentence Reading (United States)

    Brocher, Andreas; Foraker, Stephani; Koenig, Jean-Pierre


    The degree to which meanings are related in memory affects ambiguous word processing. We examined irregular polysemes, which have related senses based on similar or shared features rather than a relational rule, like regular polysemy. We tested to what degree the related meanings of irregular polysemes ("wire") are represented with…

  6. Ethical issues in irregular migration research

    NARCIS (Netherlands)

    Duvell, F.; Triandafyllidou, A.; Vollmer, B.


    This paper is concerned with the ethical issues arising for researchers engaged in the study of irregular migration. Irregular migration is by definition an elusive phenomenon as it takes place in violation of the law and at the margins of society. This very nature of the phenomenon raises important

  7. Exploring health implications associated with irregular migration ...

    African Journals Online (AJOL)

    Although there have been several negative media reports on the plight of irregular migrants from Ghana, research on issues related to their health has been rather scanty. The study assesses health implications associated with irregular migration from Ghana using both the Techiman and Nkoranza Municipalities as a case ...

  8. Damped long-term host-parasite Red Queen coevolutionary dynamics: a reflection of dilution effects? (United States)

    Decaestecker, Ellen; De Gersem, Herbert; Michalakis, Yannis; Raeymaekers, Joost A M


    An increase in biological diversity leads to a greater stability of ecosystem properties. For host-parasite interactions, this is illustrated by the 'dilution effect': a negative correlation between host biodiversity and disease risk. We show that a similar mechanism might stabilise host-parasite dynamics at a lower level of diversity, i.e. at the level of genetic diversity within host species. A long-term time shift experiment, based on a historical reconstruction of a Daphnia-parasite coevolution, reveals infectivity cycles with more stable amplitude in experienced than in naive hosts. Coevolutionary models incorporating an increase in host allelic diversity over time explain the detected asymmetry. The accumulation of resistance alleles creates an opportunity for the host to stabilise Red Queen dynamics. It leads to a larger arsenal enhancing the host performance in its coevolution with the parasite in which 'it takes all the running both antagonists can do to keep in the same place'. © 2013 John Wiley & Sons Ltd/CNRS.

  9. Coevolutionary interactions between farmers and mafia induce host acceptance of avian brood parasites. (United States)

    Abou Chakra, Maria; Hilbe, Christian; Traulsen, Arne


    Brood parasites exploit their host in order to increase their own fitness. Typically, this results in an arms race between parasite trickery and host defence. Thus, it is puzzling to observe hosts that accept parasitism without any resistance. The 'mafia' hypothesis suggests that these hosts accept parasitism to avoid retaliation. Retaliation has been shown to evolve when the hosts condition their response to mafia parasites, who use depredation as a targeted response to rejection. However, it is unclear if acceptance would also emerge when 'farming' parasites are present in the population. Farming parasites use depredation to synchronize the timing with the host, destroying mature clutches to force the host to re-nest. Herein, we develop an evolutionary model to analyse the interaction between depredatory parasites and their hosts. We show that coevolutionary cycles between farmers and mafia can still induce host acceptance of brood parasites. However, this equilibrium is unstable and in the long-run the dynamics of this host-parasite interaction exhibits strong oscillations: when farmers are the majority, accepters conditional to mafia (the host will reject first and only accept after retaliation by the parasite) have a higher fitness than unconditional accepters (the host always accepts parasitism). This leads to an increase in mafia parasites' fitness and in turn induce an optimal environment for accepter hosts.

  10. Ship Pipe Routing Design Using NSGA-II and Coevolutionary Algorithm

    Directory of Open Access Journals (Sweden)

    Wentie Niu


    Full Text Available Pipe route design plays a prominent role in ship design. Due to the complex configuration in layout space with numerous pipelines, diverse design constraints, and obstacles, it is a complicated and time-consuming process to obtain the optimal route of ship pipes. In this article, an optimized design method for branch pipe routing is proposed to improve design efficiency and to reduce human errors. By simplifying equipment and ship hull models and dividing workspace into three-dimensional grid cells, the mathematic model of layout space is constructed. Based on the proposed concept of pipe grading method, the optimization model of pipe routing is established. Then an optimization procedure is presented to deal with pipe route planning problem by combining maze algorithm (MA, nondominated sorting genetic algorithm II (NSGA-II, and cooperative coevolutionary nondominated sorting genetic algorithm II (CCNSGA-II. To improve the performance in genetic algorithm procedure, a fixed-length encoding method is presented based on improved maze algorithm and adaptive region strategy. Fuzzy set theory is employed to extract the best compromise pipeline from Pareto optimal solutions. Simulation test of branch pipe and design optimization of a fuel piping system were carried out to illustrate the design optimization procedure in detail and to verify the feasibility and effectiveness of the proposed methodology.

  11. Reciprocal selection causes a coevolutionary arms race between crossbills and lodgepole pine. (United States)

    Benkman, Craig W; Parchman, Thomas L; Favis, Amanda; Siepielski, Adam M


    Few studies have shown both reciprocal selection and reciprocal adaptations for a coevolving system in the wild. The goal of our study was to determine whether the patterns of selection on Rocky Mountain lodgepole pine (Pinus contorta spp. latifolia) and red crossbills (Loxia curvirostra complex) were concordant with earlier published evidence of reciprocal adaptations in lodgepole pine and crossbills on isolated mountain ranges in the absence of red squirrels (Tamiasciurus hudsonicus). We found that selection (directional) by crossbills on lodgepole pine where Tamiasciurus are absent was divergent from the selection (directional) exerted by Tamiasciurus on lodgepole pine. This resulted in divergent selection between areas with and without Tamiasciurus that was congruent with the geographic patterns of cone variation. In the South Hills, Idaho, where Tamiasciurus are absent and red crossbills are thought to be coevolving with lodgepole pine, crossbills experienced stabilizing selection on bill size, with cone structure as the agent of selection. These results show that crossbills and lodgepole pine exhibit reciprocal adaptations in response to reciprocal selection, and they provide insight into the traits mediating and responding to selection in a coevolutionary arms race.

  12. A further analysis of the role of heterogeneity in coevolutionary spatial games (United States)

    Cardinot, Marcos; Griffith, Josephine; O'Riordan, Colm


    Heterogeneity has been studied as one of the most common explanations of the puzzle of cooperation in social dilemmas. A large number of papers have been published discussing the effects of increasing heterogeneity in structured populations of agents, where it has been established that heterogeneity may favour cooperative behaviour if it supports agents to locally coordinate their strategies. In this paper, assuming an existing model of a heterogeneous weighted network, we aim to further this analysis by exploring the relationship (if any) between heterogeneity and cooperation. We adopt a weighted network which is fully populated by agents playing both the Prisoner's Dilemma or the Optional Prisoner's Dilemma games with coevolutionary rules, i.e., not only the strategies but also the link weights evolve over time. Surprisingly, results show that the heterogeneity of link weights (states) on their own does not always promote cooperation; rather cooperation is actually favoured by the increase in the number of overlapping states and not by the heterogeneity itself. We believe that these results can guide further research towards a more accurate analysis of the role of heterogeneity in social dilemmas.

  13. Sequence-based antigenic change prediction by a sparse learning method incorporating co-evolutionary information.

    Directory of Open Access Journals (Sweden)

    Jialiang Yang

    Full Text Available Rapid identification of influenza antigenic variants will be critical in selecting optimal vaccine candidates and thus a key to developing an effective vaccination program. Recent studies suggest that multiple simultaneous mutations at antigenic sites accumulatively enhance antigenic drift of influenza A viruses. However, pre-existing methods on antigenic variant identification are based on analyses from individual sites. Because the impacts of these co-evolved sites on influenza antigenicity may not be additive, it will be critical to quantify the impact of not only those single mutations but also multiple simultaneous mutations or co-evolved sites. Here, we developed and applied a computational method, AntigenCO, to identify and quantify both single and co-evolutionary sites driving the historical antigenic drifts. AntigenCO achieved an accuracy of up to 90.05% for antigenic variant prediction, significantly outperforming methods based on single sites. AntigenCO can be useful in antigenic variant identification in influenza surveillance.

  14. Testing co-evolutionary hypotheses over geological timescales: interactions between Mesozoic non-avian dinosaurs and cycads. (United States)

    Butler, Richard J; Barrett, Paul M; Kenrick, Paul; Penn, Malcolm G


    The significance of co-evolution over ecological timescales is well established, yet it remains unclear to what extent co-evolutionary processes contribute to driving large-scale evolutionary and ecological changes over geological timescales. Some of the most intriguing and pervasive long-term co-evolutionary hypotheses relate to proposed interactions between herbivorous non-avian dinosaurs and Mesozoic plants, including cycads. Dinosaurs have been proposed as key dispersers of cycad seeds during the Mesozoic, and temporal variation in cycad diversity and abundance has been linked to dinosaur faunal changes. Here we assess the evidence for proposed hypotheses of trophic and evolutionary interactions between these two groups using diversity analyses, a new database of Cretaceous dinosaur and plant co-occurrence data, and a geographical information system (GIS) as a visualisation tool. Phylogenetic evidence suggests that the origins of several key biological properties of cycads (e.g. toxins, bright-coloured seeds) likely predated the origin of dinosaurs. Direct evidence of dinosaur-cycad interactions is lacking, but evidence from extant ecosystems suggests that dinosaurs may plausibly have acted as seed dispersers for cycads, although it is likely that other vertebrate groups (e.g. birds, early mammals) also played a role. Although the Late Triassic radiations of dinosaurs and cycads appear to have been approximately contemporaneous, few significant changes in dinosaur faunas coincide with the late Early Cretaceous cycad decline. No significant spatiotemporal associations between particular dinosaur groups and cycads can be identified - GIS visualisation reveals disparities between the spatiotemporal distributions of some dinosaur groups (e.g. sauropodomorphs) and cycads that are inconsistent with co-evolutionary hypotheses. The available data provide no unequivocal support for any of the proposed co-evolutionary interactions between cycads and herbivorous dinosaurs

  15. Capture of irregular satellites at Jupiter

    Energy Technology Data Exchange (ETDEWEB)

    Nesvorný, David; Vokrouhlický, David; Deienno, Rogerio [Department of Space Studies, Southwest Research Institute, 1050 Walnut Street, Suite 300, Boulder, CO 80302 (United States)


    The irregular satellites of outer planets are thought to have been captured from heliocentric orbits. The exact nature of the capture process, however, remains uncertain. We examine the possibility that irregular satellites were captured from the planetesimal disk during the early solar system instability when encounters between the outer planets occurred. Nesvorný et al. already showed that the irregular satellites of Saturn, Uranus, and Neptune were plausibly captured during planetary encounters. Here we find that the current instability models present favorable conditions for capture of irregular satellites at Jupiter as well, mainly because Jupiter undergoes a phase of close encounters with an ice giant. We show that the orbital distribution of bodies captured during planetary encounters provides a good match to the observed distribution of irregular satellites at Jupiter. The capture efficiency for each particle in the original transplanetary disk is found to be (1.3-3.6) × 10{sup –8}. This is roughly enough to explain the observed population of jovian irregular moons. We also confirm Nesvorný et al.'s results for the irregular satellites of Saturn, Uranus, and Neptune.

  16. Dual transcriptomics reveals co-evolutionary mechanisms of intestinal parasite infections in blue mussels Mytilus edulis. (United States)

    Feis, Marieke E; John, Uwe; Lokmer, Ana; Luttikhuizen, Pieternella C; Wegner, K Mathias


    On theoretical grounds, antagonistic co-evolution between hosts and their parasites should be a widespread phenomenon but only received little empirical support so far. Consequently, the underlying molecular mechanisms and evolutionary steps remain elusive, especially in nonmodel systems. Here, we utilized the natural history of invasive parasites to document the molecular underpinnings of co-evolutionary trajectories. We applied a dual-species transcriptomics approach to experimental cross-infections of blue mussel Mytilus edulis hosts and their invasive parasitic copepods Mytilicola intestinalis from two invasion fronts in the Wadden Sea. We identified differentially regulated genes from an experimental infection contrast for hosts (infected vs. control) and a sympatry contrast (sympatric vs. allopatric combinations) for both hosts and parasites. The damage incurred by Mytilicola infection and the following immune response of the host were mainly reflected in cell division processes, wound healing, apoptosis and the production of reactive oxygen species (ROS). Furthermore, the functional coupling of host and parasite sympatry contrasts revealed the concerted regulation of chitin digestion by a Chitotriosidase 1 homolog in hosts with several cuticle proteins in the parasite. Together with the coupled regulation of ROS producers and antagonists, these genes represent candidates that mediate the different evolutionary trajectories within the parasite's invasion. The host-parasite combination-specific coupling of these effector mechanisms suggests that underlying recognition mechanisms create specificity and local adaptation. In this way, our study demonstrates the use of invasive species' natural history to elucidate molecular mechanisms of host-parasite co-evolution in the wild. © 2018 The Authors. Molecular Ecology Published by John Wiley & Sons Ltd.

  17. A molecular and co-evolutionary context for grazer induced toxin production in Alexandrium tamarense. (United States)

    Wohlrab, Sylke; Iversen, Morten H; John, Uwe


    Marine dinoflagellates of the genus Alexandrium are the proximal source of neurotoxins associated with Paralytic Shellfish Poisoning. The production of these toxins, the toxin biosynthesis and, thus, the cellular toxicity can be influenced by abiotic and biotic factors. There is, however, a lack of substantial evidence concerning the toxins' ecological function such as grazing defense. Waterborne cues from copepods have been previously found to induce a species-specific increase in toxin content in Alexandrium minutum. However, it remains speculative in which context these species-specific responses evolved and if it occurs in other Alexandrium species as well. In this study we exposed Alexandrium tamarense to three copepod species (Calanus helgolandicus, Acartia clausii, and Oithona similis) and their corresponding cues. We show that the species-specific response towards copepod-cues is not restricted to one Alexandrium species and that co-evolutionary processes might be involved in these responses, thus giving additional evidence for the defensive role of phycotoxins. Through a functional genomic approach we gained insights into the underlying molecular processes which could trigger the different outcomes of these species-specific responses and consequently lead to increased toxin content in Alexandrium tamarense. We propose that the regulation of serine/threonine kinase signaling pathways has a major influence in directing the external stimuli i.e. copepod-cues, into different intracellular cascades and networks in A. tamarense. Our results show that A. tamarense can sense potential predating copepods and respond to the received information by increasing its toxin production. Furthermore, we demonstrate how a functional genomic approach can be used to investigate species interactions within the plankton community.

  18. A molecular and co-evolutionary context for grazer induced toxin production in Alexandrium tamarense.

    Directory of Open Access Journals (Sweden)

    Sylke Wohlrab

    Full Text Available Marine dinoflagellates of the genus Alexandrium are the proximal source of neurotoxins associated with Paralytic Shellfish Poisoning. The production of these toxins, the toxin biosynthesis and, thus, the cellular toxicity can be influenced by abiotic and biotic factors. There is, however, a lack of substantial evidence concerning the toxins' ecological function such as grazing defense. Waterborne cues from copepods have been previously found to induce a species-specific increase in toxin content in Alexandrium minutum. However, it remains speculative in which context these species-specific responses evolved and if it occurs in other Alexandrium species as well. In this study we exposed Alexandrium tamarense to three copepod species (Calanus helgolandicus, Acartia clausii, and Oithona similis and their corresponding cues. We show that the species-specific response towards copepod-cues is not restricted to one Alexandrium species and that co-evolutionary processes might be involved in these responses, thus giving additional evidence for the defensive role of phycotoxins. Through a functional genomic approach we gained insights into the underlying molecular processes which could trigger the different outcomes of these species-specific responses and consequently lead to increased toxin content in Alexandrium tamarense. We propose that the regulation of serine/threonine kinase signaling pathways has a major influence in directing the external stimuli i.e. copepod-cues, into different intracellular cascades and networks in A. tamarense. Our results show that A. tamarense can sense potential predating copepods and respond to the received information by increasing its toxin production. Furthermore, we demonstrate how a functional genomic approach can be used to investigate species interactions within the plankton community.

  19. Locating irregularly shaped clusters of infection intensity

    DEFF Research Database (Denmark)

    Yiannakoulias, Niko; Wilson, Shona; Kariuki, H. Curtis


    Patterns of disease may take on irregular geographic shapes, especially when features of the physical environment influence risk. Identifying these patterns can be important for planning, and also identifying new environmental or social factors associated with high or low risk of illness. Until...... recently, cluster detection methods were limited in their ability to detect irregular spatial patterns, and limited to finding clusters that were roughly circular in shape. This approach has less power to detect irregularly-shaped, yet important spatial anomalies, particularly at high spatial resolutions....... We employ a new method of finding irregularly-shaped spatial clusters at micro-geographical scales using both simulated and real data on Schistosoma mansoni and hookworm infection intensities. This method, which we refer to as the "greedy growth scan", is a modification of the spatial scan method...

  20. Examining U.S. Irregular Warfare Doctrine

    National Research Council Canada - National Science Library

    Kimbrough, IV, James M


    ... of insurgency and terrorism. In response to the associated strategic challenges, a growing debate occurred among military historians, strategists, and leaders about the proper principles necessary for contemporary irregular...

  1. Enhancing locality in Java based irregular applications


    Faria, Nuno Filipe Monteiro; Silva, Rui C.; Sobral, João Luís Ferreira


    Improving locality of memory accesses in current and future multi-core platforms is a key to efficiently exploit those platforms. Irregular applications, which operate on pointer-based data structures, are hard to optimize in modern computer architectures due to their intrinsic unpredictable patterns of memory accesses. In this paper we explore a memory locality-driven set of data-structures in order to attenuate the memory bandwidth limitations from typical irregular algorithms. We identify ...

  2. The K-Spectrum of Ionospheric Irregularities

    DEFF Research Database (Denmark)

    D'Angelo, N.; Pécseli, Hans; Petersen, P. I.


    Laboratory measurements in a cesium plasma device indicate that the wave number (power) spectrum of irregularities produced by the Farley instability is of the type P(K) ∝ K −β, where β ≃ 3.5-3.8.......Laboratory measurements in a cesium plasma device indicate that the wave number (power) spectrum of irregularities produced by the Farley instability is of the type P(K) ∝ K −β, where β ≃ 3.5-3.8....

  3. Locating irregularly shaped clusters of infection intensity

    Directory of Open Access Journals (Sweden)

    Niko Yiannakoulias


    Full Text Available Patterns of disease may take on irregular geographic shapes, especially when features of the physical environment influence risk. Identifying these patterns can be important for planning, and also identifying new environmental or social factors associated with high or low risk of illness. Until recently, cluster detection methods were limited in their ability to detect irregular spatial patterns, and limited to finding clusters that were roughly circular in shape. This approach has less power to detect irregularly-shaped, yet important spatial anomalies, particularly at high spatial resolutions. We employ a new method of finding irregularly-shaped spatial clusters at micro-geographical scales using both simulated and real data on Schistosoma mansoni and hookworm infection intensities. This method, which we refer to as the “greedy growth scan”, is a modification of the spatial scan method for cluster detection. Real data are based on samples of hookworm and S. mansoni from Kitengei, Makueni district, Kenya. Our analysis of simulated data shows how methods able to find irregular shapes are more likely to identify clusters along rivers than methods constrained to fixed geometries. Our analysis of infection intensity identifies two small areas within the study region in which infection intensity is elevated, possibly due to local features of the physical or social environment. Collectively, our results show that the “greedy growth scan” is a suitable method for exploratory geographical analysis of infection intensity data when irregular shapes are suspected, especially at micro-geographical scales.

  4. A Co-evolutionary perspective on the Drivers of International Sourcing of Pharmaceutical R&D to India

    DEFF Research Database (Denmark)

    Haakonsson, Stine Jessen; Ørberg Jensen, Peter D.; M. Mudambi, Susan


    The attractiveness of the Indian pharmaceutical industry as a destination for R&D sourcing by multinational corporations (MNCs) has evolved over the past decades. This evolution has coincided with changes in MNC strategies regarding sourcing location and governance modes. We propose a co-evolutionary...... theory perspective embracing both firm-internal and firm-environmental factors for location attractiveness, along with institutional and industry changes. The framework integrates constructs from past research in economic geography, international business, and R&D internationalization. The Indian case...

  5. Approaches to understanding the impact of life-history features on plant-pathogen co-evolutionary dynamics (United States)

    Jeremy J. Burdon; Peter H. Thrall; Adnane Nemri


    Natural plant-pathogen associations are complex interactions in which the interplay of environment, host, and pathogen factors results in spatially heterogeneous ecological and epidemiological dynamics. The evolutionary patterns that result from the interaction of these factors are still relatively poorly understood. Recently, integration of the appropriate spatial and...


    Directory of Open Access Journals (Sweden)

    V. T. Cheshko


    Full Text Available Purpose (metatask of the present work is to attempt to give a glance at the problem of existential and anthropological risk caused by the contemporary man-made civilization from the perspective of comparison and confrontation of aesthetics, the substrate of which is emotional and metaphorical interpretation of individual subjective values and politics feeding by objectively rational interests of social groups. In both cases there is some semantic gap present between the represented social reality and its representation in perception of works of art and in the political doctrines as well. Methodology of the research is evolutionary anthropologicalcomparativistics. Originality of the conducted analysis comes to the following: As the antithesis to biological and social reductionism in interpretation of the phenomenon of bio-power it is proposed a co-evolutionary semantic model in accordance with which the described semantic gap is of the substantial nature related to the complex module organization of a consistent and adaptive human strategy consisting of three associated but independently functional modules (genetic, cultural and techno-rational. Evolutionary trajectory of all anthropogenesis components including civilization cultural and social-political evolution is identified by the proportion between two macro variables – evolutionary effectiveness and evolutionary stability (sameness, i.e. preservation in the context of consequential transformations of some invariants of Homo sapiens species specificity organization. It should be noted that inasmuch as in respect to human, some modules of the evolutionary (adaptive strategy assume self-reflection attributes, it would be more correctly to state about evolutionary correctness, i.e. correspondence to some perfection. As a result, the future of human nature depends not only on the rationalist principles of ethics of Homo species (the archaism of Jurgen Habermas, but also on the holistic and

  7. Composition of Jupiter irregular satellites sheds light on their origin (United States)

    Bhatt, M.; Reddy, V.; Schindler, K.; Cloutis, E.; Bhardwaj, A.; Corre, L. L.; Mann, P.


    Context. Irregular satellites of Jupiter with their highly eccentric, inclined and distant orbits suggest that their capture took place after the giant planet migration. Aims: We aim to improve our understanding of the surface composition of irregular satellites of Jupiter to gain insight into a narrow time window when our solar system was forming. Methods: We observed three Jovian irregular satellites, Himalia (JVI), Elara (JVII), and Carme (JXI), using a medium-resolution 0.8-5.5 μm spectrograph, SpeX on the NASA Infrared Telescope Facility (IRTF). Using a linear spectral unmixing model we have constrained the major mineral phases on the surface of these three bodies. Results: Our results confirm that the surface of Himalia (JVI), Elara (JVII), and Carme (JXI) are dominated by opaque materials such as those seen in carbonaceous chondrite meteorites. Our spectral modeling of NIR spectra of Himalia and Elara confirm that their surface composition is the same and magnetite is the dominant mineral. A comparison of the spectral shape of Himalia with the two large main C-type asteroids, Themis (D 176 km) and Europa (D 352 km), suggests surface composition similar to Europa. The NIR spectrum of Carme exhibits blue slope up to 1.5 μm and is spectrally distinct from those of Himalia and Elara. Our model suggests that it is compositionally similar to amorphous carbon. Conclusions: Himalia and Elara are compositionally similar but differ significantly from Carme. These results support the hypotheses that the Jupiter's irregular satellites are captured bodies that were subject to further breakup events and clustered as families based on their similar physical and surface compositions.

  8. Locating irregularly shaped clusters of infection intensity

    DEFF Research Database (Denmark)

    Yiannakoulias, Niko; Wilson, Shona; Kariuki, H. Curtis


    . We employ a new method of finding irregularly-shaped spatial clusters at micro-geographical scales using both simulated and real data on Schistosoma mansoni and hookworm infection intensities. This method, which we refer to as the "greedy growth scan", is a modification of the spatial scan method...... of infection intensity identifies two small areas within the study region in which infection intensity is elevated, possibly due to local features of the physical or social environment. Collectively, our results show that the "greedy growth scan" is a suitable method for exploratory geographical analysis...... of infection intensity data when irregular shapes are suspected, especially at micro-geographical scales....

  9. High energy model for irregular absorbing particles

    International Nuclear Information System (INIS)

    Chiappetta, Pierre.


    In the framework of a high energy formulation of relativistic quantum scattering a model is presented which describes the scattering functions and polarization of irregular absorbing particles, whose dimensions are greater than the incident wavelength. More precisely in the forward direction an amplitude parametrization of eikonal type is defined which generalizes the usual diffraction theory, and in the backward direction a reflective model is used including a shadow function. The model predictions are in good agreement with the scattering measurements off irregular compact and fluffy particles performed by Zerull, Giese and Weiss (1977)

  10. Advances in electron dosimetry of irregular fields

    International Nuclear Information System (INIS)

    Mendez V, J.


    In this work it is presented an advance in Electron dosimetry of irregular fields for beams emitted by linear accelerators. At present diverse methods exist which are coming to apply in the Radiotherapy centers. In this work it is proposed a method for irregular fields dosimetry. It will be allow to calculate the dose rate absorbed required for evaluating the time for the treatment of cancer patients. Utilizing the results obtained by the dosimetric system, it has been possible to prove the validity of the method describe for 12 MeV energy and for square field 7.5 x 7.5 cm 2 with percentile error less than 1 % . (Author)

  11. Structure Irregularity Impedes Drop Roll-Off at Superhydrophobic Surfaces

    DEFF Research Database (Denmark)

    Larsen, Simon Tylsgaard; Andersen, Nis Korsgaard; Søgaard, Emil


    -off angles is found to be caused by a decrease of the receding contact angle, which in turn is caused by an increase of the triple phase contact line of the drops for those more irregular surfaces. To understand the observation, we propose to treat the microdrops as rigid bodies and apply a torque balance...... between the torque exerted by the projected gravity force and the torque exerted by the adhesion force acting along the triple line on the receding side of the drop. This simple model provides a proper order of magnitude estimate of the measured effects....

  12. Holding Irregularly Shaped Parts For Machining (United States)

    Hilton, Burt W.; Wilson, Rick R.


    Part with complicated, irregular outside contours clamped for precise machining of internal passages with aid of simple method. Exterior of part cast in Rigidex, or equivalent epoxy. Forms wall to be clamped. Interior of part machined to finish of 125 microinches or finer. When machining finished, epoxy melted away by heating part to 200 degree F.

  13. Linking Poverty, Irregular Migration and Human Trafficking ...

    African Journals Online (AJOL)

    Migration literature suggests that poverty, irregular migration and human trafficking are causally linked. However, empirical studies linking these aspects of migration are scarce. This is because, as clandestine activities, data collection on these aspects of migration presents serious challenges. As a result of these ...

  14. Exploring health implications associated with irregular migration ...

    African Journals Online (AJOL)

    further their education after the Junior High School or Senior High School. Keywords: Health, irregular migration, youngpeople, Libya, Ghana. eDepartment of Population and Health, University of Cape Coast, Cape Coast, Ghana. E-mail: Ghana Journal of Geography Vol.4, 2012 Pages 65 - 82. 65 ...

  15. Synchronizing data from irregularly sampled sensors (United States)

    Uluyol, Onder


    A system and method include receiving a set of sampled measurements for each of multiple sensors, wherein the sampled measurements are at irregular intervals or different rates, re-sampling the sampled measurements of each of the multiple sensors at a higher rate than one of the sensor's set of sampled measurements, and synchronizing the sampled measurements of each of the multiple sensors.

  16. Smoking and respiratory irregularity in panic disorder. (United States)

    Caldirola, Daniela; Bellodi, Laura; Cammino, Stefania; Perna, Giampaolo


    The biological mechanisms underlying the link between smoking and panic attacks are unknown. Smoking might increase the risk of panic by impairing respiratory system function. We evaluated the effect of smoking on respiratory irregularity in patients with panic disorder (PD) and healthy comparison subjects and the role of the respiratory disorders in this effect. We applied the Approximate Entropy index (ApEn), a nonlinear measure of irregularity, to study breath-by-breath baseline respiratory patterns in our sample. Both smoker and nonsmoker patients had more irregular respiratory patterns than healthy subjects. Smoker patients showed higher ApEn indices of baseline respiratory rate and tidal volume than nonsmoker patients (R = 5.4, df = 2,55, p smoking in healthy subjects did not influence the regularity of respiratory patterns. Respiratory disorders did not account for the influence of smoking on respiratory irregularity. Smokers had more severe panic attacks than nonsmokers. Smoking may impair vulnerable respiratory function and act as disruptive factor on intrinsic baseline respiratory instability in patients with PD, possibly influencing the onset or maintenance of the disorder.

  17. Natural convection inside an irregular porous cavity

    International Nuclear Information System (INIS)

    Beltran, Jorge I. LLagostera; Trevisan, Osvair Vidal


    Natural convection flow induced by heating from below in a irregular porous cavity is investigated numerically. The influence of the modified Rayleigh number and geometric ratios on heat transfer and fluid flow is studied. Global and local Nusselt for Rayleigh numbers covering the range 0 - 1600 and for several geometric ratios. The fluid flow and the temperature field are illustrated by contour maps. (author)

  18. Distributed parallel cooperative coevolutionary multi-objective large-scale immune algorithm for deployment of wireless sensor networks

    DEFF Research Database (Denmark)

    Cao, Bin; Zhao, Jianwei; Yang, Po


    Using immune algorithms is generally a time-intensive process especially for problems with a large number of variables. In this paper, we propose a distributed parallel cooperative coevolutionary multi-objective large-scale immune algorithm that is implemented using the message passing interface...... number of variables are divided into several groups. Finally, individual evaluations are allocated across many core processing units, and calculations are performed in parallel. Consequently, the computation time is greatly reduced. The proposed algorithm integrates the idea of immune algorithms, which...... (MPI). The proposed algorithm is composed of three layers: objective, group and individual layers. First, for each objective in the multi-objective problem to be addressed, a subpopulation is used for optimization, and an archive population is used to optimize all the objectives. Second, the large...

  19. Generating Performance Models for Irregular Applications

    Energy Technology Data Exchange (ETDEWEB)

    Friese, Ryan D.; Tallent, Nathan R.; Vishnu, Abhinav; Kerbyson, Darren J.; Hoisie, Adolfy


    Many applications have irregular behavior --- non-uniform input data, input-dependent solvers, irregular memory accesses, unbiased branches --- that cannot be captured using today's automated performance modeling techniques. We describe new hierarchical critical path analyses for the \\Palm model generation tool. To create a model's structure, we capture tasks along representative MPI critical paths. We create a histogram of critical tasks with parameterized task arguments and instance counts. To model each task, we identify hot instruction-level sub-paths and model each sub-path based on data flow, instruction scheduling, and data locality. We describe application models that generate accurate predictions for strong scaling when varying CPU speed, cache speed, memory speed, and architecture. We present results for the Sweep3D neutron transport benchmark; Page Rank on multiple graphs; Support Vector Machine with pruning; and PFLOTRAN's reactive flow/transport solver with domain-induced load imbalance.

  20. Investigation of ionospheric irregularities by radio holography (United States)

    Tereshchenko, E. D.; Popov, A. A.; Tereshchenko, A. D.; Khudukon, B. Z.

    Methodological aspects of the design of a radio-holography experiment for the investigation of ionospheric irregularities are considered on the basis of a theoretical examination of the formation of a diffraction field by two coherent satellite signals. The equipment needed to implement such an experiment is described, and results of first observations performed at high latitudes (in the Murmansk region) on February 8, 1978 are examined.

  1. Star formation histories of irregular galaxies

    International Nuclear Information System (INIS)

    Gallagher, J.S. III; Hunter, D.A.; Tutukov, A.V.


    We explore the star formation histories of a selection of irregular and spiral galaxies by using three parameters that sample the star formation rate (SFR) at different epochs: (1) the mass of a galaxy in the form of stars measures the SFR integrated over a galaxy's lifetime; (2) the blue luminosity is dominated primarily by stars formed over the past few billion years; and (3) Lyman continuum photon fluxes derived from Hα luminosities give the current ( 8 yr) SFR

  2. Parallel Computing Strategies for Irregular Algorithms (United States)

    Biswas, Rupak; Oliker, Leonid; Shan, Hongzhang; Biegel, Bryan (Technical Monitor)


    Parallel computing promises several orders of magnitude increase in our ability to solve realistic computationally-intensive problems, but relies on their efficient mapping and execution on large-scale multiprocessor architectures. Unfortunately, many important applications are irregular and dynamic in nature, making their effective parallel implementation a daunting task. Moreover, with the proliferation of parallel architectures and programming paradigms, the typical scientist is faced with a plethora of questions that must be answered in order to obtain an acceptable parallel implementation of the solution algorithm. In this paper, we consider three representative irregular applications: unstructured remeshing, sparse matrix computations, and N-body problems, and parallelize them using various popular programming paradigms on a wide spectrum of computer platforms ranging from state-of-the-art supercomputers to PC clusters. We present the underlying problems, the solution algorithms, and the parallel implementation strategies. Smart load-balancing, partitioning, and ordering techniques are used to enhance parallel performance. Overall results demonstrate the complexity of efficiently parallelizing irregular algorithms.

  3. Organizing for Irregular Warfare: Implications for the Brigade Combat Team

    National Research Council Canada - National Science Library

    Burgess, Kenneth J


    ... operations in 21st-century irregular environments. The author argues that Infantry Brigade Combat Teams would be better optimized for the challenges of irregular warfare through structural changes that decentralize resources...

  4. Propagation of shear waves in an irregular magnetoelastic ...

    African Journals Online (AJOL)

    type wave equation, for isotropic layer sandwiched between two isotropic half spaces, in the absence of magnetic field and irregularity. The effects of depth of irregularity and monoclinic-magnetoelastic coupling parameters on dispersion curves ...

  5. Irregular Female Migrant Workers along Lao-Thai Borders




    This thesis focuses on irregular migration from Laos to Thailand, and irregular migrant labour in Thailand. This research is set in Mukdahan – a small (in size and population) yet important province as a gateway to cross-border activities in the Mekong region. It draws on the experiences of Lao irregular female migrant labourers in Mukdahan, northeastern Thailand, and the practices and perspectives of Thai authorities and employers in relation to irregular migrant labour law and enforcement. ...

  6. 16 CFR 501.6 - Cellulose sponges, irregular dimensions. (United States)


    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Cellulose sponges, irregular dimensions. 501... REQUIREMENTS AND PROHIBITIONS UNDER PART 500 § 501.6 Cellulose sponges, irregular dimensions. Variety packages of cellulose sponges of irregular dimensions, are exempted from the requirements of § 500.25 of this...

  7. Kilometer-Spaced GNSS Array for Ionospheric Irregularity Monitoring (United States)

    Su, Yang

    This dissertation presents automated, systematic data collection, processing, and analysis methods for studying the spatial-temporal properties of Global Navigation Satellite Systems (GNSS) scintillations produced by ionospheric irregularities at high latitudes using a closely spaced multi-receiver array deployed in the northern auroral zone. The main contributions include 1) automated scintillation monitoring, 2) estimation of drift and anisotropy of the irregularities, 3) error analysis of the drift estimates, and 4) multi-instrument study of the ionosphere. A radio wave propagating through the ionosphere, consisting of ionized plasma, may suffer from rapid signal amplitude and/or phase fluctuations known as scintillation. Caused by non-uniform structures in the ionosphere, intense scintillation can lead to GNSS navigation and high-frequency (HF) communication failures. With specialized GNSS receivers, scintillation can be studied to better understand the structure and dynamics of the ionospheric irregularities, which can be parameterized by altitude, drift motion, anisotropy of the shape, horizontal spatial extent and their time evolution. To study the structuring and motion of ionospheric irregularities at the sub-kilometer scale sizes that produce L-band scintillations, a closely-spaced GNSS array has been established in the auroral zone at Poker Flat Research Range, Alaska to investigate high latitude scintillation and irregularities. Routinely collecting low-rate scintillation statistics, the array database also provides 100 Hz power and phase data for each channel at L1/L2C frequency. In this work, a survey of seasonal and hourly dependence of L1 scintillation events over the course of a year is discussed. To efficiently and systematically study scintillation events, an automated low-rate scintillation detection routine is established and performed for each day by screening the phase scintillation index. The spaced-receiver technique is applied to cross

  8. Learning Adaptive Forecasting Models from Irregularly Sampled Multivariate Clinical Data. (United States)

    Liu, Zitao; Hauskrecht, Milos


    Building accurate predictive models of clinical multivariate time series is crucial for understanding of the patient condition, the dynamics of a disease, and clinical decision making. A challenging aspect of this process is that the model should be flexible and adaptive to reflect well patient-specific temporal behaviors and this also in the case when the available patient-specific data are sparse and short span. To address this problem we propose and develop an adaptive two-stage forecasting approach for modeling multivariate, irregularly sampled clinical time series of varying lengths. The proposed model (1) learns the population trend from a collection of time series for past patients; (2) captures individual-specific short-term multivariate variability; and (3) adapts by automatically adjusting its predictions based on new observations. The proposed forecasting model is evaluated on a real-world clinical time series dataset. The results demonstrate the benefits of our approach on the prediction tasks for multivariate, irregularly sampled clinical time series, and show that it can outperform both the population based and patient-specific time series prediction models in terms of prediction accuracy.

  9. Influence of initial stress, irregularity and heterogeneity on Love-type ...

    Indian Academy of Sciences (India)

    Regulation of seismic wave propagation due to structural deformations of the boundary of elastic medium, in which it is ... gation of seismic waves in an elastic medium with divergent irregularities in order to understand and ...... Graphical interpretation of dispersion curve ref- lecting the effect of different affecting parameters,.

  10. Tracking objects with the bounded irregular pyramid


    Marfil Robles, Rebeca


    En esta tesis se propone un sistema de seguimiento de objetos basados en un nuevo método de representación y localización del objetivo. Se trata de realizar el seguimiento de objetos no rígidos en tiempo real, sin utilizar ningún modelo previo de los objetos a seguir. Para conseguir esto, se propone un nuevo modelo para caracterizar la apariencia del objeto basado en una máscara o template. Este modelo utiliza una nueva estructura piramidal, denominada Bounded Irregular Pyramid (BIP), p...

  11. Rectilinear partitioning of irregular data parallel computations (United States)

    Nicol, David M.


    New mapping algorithms for domain oriented data-parallel computations, where the workload is distributed irregularly throughout the domain, but exhibits localized communication patterns are described. Researchers consider the problem of partitioning the domain for parallel processing in such a way that the workload on the most heavily loaded processor is minimized, subject to the constraint that the partition be perfectly rectilinear. Rectilinear partitions are useful on architectures that have a fast local mesh network. Discussed here is an improved algorithm for finding the optimal partitioning in one dimension, new algorithms for partitioning in two dimensions, and optimal partitioning in three dimensions. The application of these algorithms to real problems are discussed.

  12. Artificial periodic irregularities in the auroral ionosphere

    Directory of Open Access Journals (Sweden)

    M. T. Rietveld


    Full Text Available Artificial periodic irregularities (API are produced in the ionospheric plasma by a powerful standing electromagnetic wave reflected off the F region. The resulting electron-density irregularities can scatter other high-frequency waves if the Bragg scattering condition is met. Such measurements have been performed at mid-latitudes for two decades and have been developed into a useful ionospheric diagnostic technique. We report here the first measurements from a high-latitude station, using the EISCAT heating facility near Tromsø, Norway. Both F-region and lower-altitude ionospheric echoes have been obtained, but the bulk of the data has been in the E and D regions with echoes extending down to 52-km altitude. Examples of API are shown, mainly from the D region, together with simultaneous VHF incoherent-scatter-radar (ISR data. Vertical velocities derived from the rate of phase change during the irregularity decay are shown and compared with velocities derived from the ISR. Some of the API-derived velocities in the 75–115-km height range appear consistent with vertical neutral winds as shown by their magnitudes and by evidence of gravity waves, while other data in the 50–70-km range show an unrealistically large bias. For a comparison with ISR data it has proved difficult to get good quality data sets overlapping in height and time. The initial comparisons show some agreement, but discrepancies of several metres per second do not yet allow us to conclude that the two techniques are measuring the same quantity. The irregularity decay time-constants between about 53 and 70 km are compared with the results of an advanced ion-chemistry model, and height profiles of recorded signal power are compared with model estimates in the same altitude range. The calculated amplitude shows good agreement with the data in that the maximum occurs at about the same height as that of the measured amplitude. The calculated time-constant agrees very well with the

  13. Legal aspects of the EU policy on irregular immigration

    Directory of Open Access Journals (Sweden)

    Voinikov Vadim


    Full Text Available This article addresses the issues pertaining to the adoption and development of legislation on irregular migration in the context of uncontrolled growth in the number of immigrants from North Africa and the Middle East to the EU. The article attempts at studying the EU legislation on irregular migration, classifying it, and analysing the prospects of EU migration legislation in the light of an increase in irregular immigration into the EU. The author systematises, classifies the current EU legislation on irregular immigration, and analyses the conditions, in which this legislation was developed. Using the legislation analysis method, the author proposes the following system of EU legislation on irregular immigration: rules preventing assistance to irregular immigration, rules preventing employment of irregular immigrants, rules on the return of irregular migrants and readmission, rules on border control, and rules on collaboration with third countries. The author pays special attention to analysing the current state of irregular immigration to the EU, which was dubbed the ‘greatest migration crisis in Europe’. The conclusion is that the European Union succeeded in the development of pioneering legislation on irregular immigration, which can serve as the basis for reception by other states. However, changes in the political and economic situation in the EU’s southern borderlands made the current legal mechanisms incapable of withstanding new threats. It necessitates a radical reform of the legislation on irregular immigration.

  14. The transition from regular to irregular motions, explained as travel on Riemann surfaces

    International Nuclear Information System (INIS)

    Calogero, F; Santini, P M; Gomez-Ullate, D; Sommacal, M


    We introduce and discuss a simple Hamiltonian dynamical system, interpretable as a three-body problem in the (complex) plane and providing the prototype of a mechanism explaining the transition from regular to irregular motions as travel on Riemann surfaces. The interest of this phenomenology-illustrating the onset in a deterministic context of irregular motions-is underlined by its generality, suggesting its eventual relevance to understand natural phenomena and experimental investigations. Here only some of our main findings are reported, without detailing their proofs: a more complete presentation will be published elsewhere

  15. Understanding Supply Networks from Complex Adaptive Systems

    Directory of Open Access Journals (Sweden)

    Jamur Johnas Marchi


    Full Text Available This theoretical paper is based on complex adaptive systems (CAS that integrate dynamic and holistic elements, aiming to discuss supply networks as complex systems and their dynamic and co-evolutionary processes. The CAS approach can give clues to understand the dynamic nature and co-evolution of supply networks because it consists of an approach that incorporates systems and complexity. This paper’s overall contribution is to reinforce the theoretical discussion of studies that have addressed supply chain issues, such as CAS.

  16. Are the metabolomic responses to folivory of closely related plant species linked to macroevolutionary and plant-folivore coevolutionary processes?

    Energy Technology Data Exchange (ETDEWEB)

    Rivas-Ubach, Albert [Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland Washington 99354 USA; CREAF, Cerdanyola del Vallès 08913 Catalonia Spain; Hódar, José A. [Grupo de Ecología Terrestre, Departamento de Biología Animal y Ecología, Facultad de Ciencias, Universidad de Granada, 18071 Granada Spain; Sardans, Jordi [CREAF, Cerdanyola del Vallès 08913 Catalonia Spain; CSIC, Global Ecology Unit CREAF-CEAB-CSIC-UAB, Cerdanyola del Vallès 08913 Catalonia Spain; Kyle, Jennifer E. [Biological Sciences Division, Pacific Northwest National Laboratory, Richland Washington 99354 USA; Kim, Young-Mo [Biological Sciences Division, Pacific Northwest National Laboratory, Richland Washington 99354 USA; Oravec, Michal [Global Change Research Centre, Academy of Sciences of the Czech Republic, Bĕlidla 4a CZ-603 00 Brno Czech Republic; Urban, Otmar [Global Change Research Centre, Academy of Sciences of the Czech Republic, Bĕlidla 4a CZ-603 00 Brno Czech Republic; Guenther, Alex [Department of Earth System Science, University of California, Irvine California 92697 USA; Peñuelas, Josep [CREAF, Cerdanyola del Vallès 08913 Catalonia Spain; CSIC, Global Ecology Unit CREAF-CEAB-CSIC-UAB, Cerdanyola del Vallès 08913 Catalonia Spain


    The debate whether the coevolution of plants and insects or macroevolutionary processes (phylogeny) is the main driver determining the arsenal of molecular defensive compounds of plants remains unresolved. Attacks by herbivorous insects affect not only the composition of defensive compounds in plants but the entire metabolome (the set of molecular metabolites), including defensive compounds. Metabolomes are the final products of genotypes and are directly affected by macroevolutionary processes, so closely related species should have similar metabolomic compositions and may respond in similar ways to attacks by folivores. We analyzed the elemental compositions and metabolomes of needles from Pinus pinaster, P. nigra and P. sylvestris to determine if these closely related Pinus species with different coevolutionary histories with the caterpillars of the processionary moth respond similarly to attacks by this lepidopteran. All pines had different metabolomes and metabolic responses to herbivorous attack. The metabolomic variation among the pine species and the responses to folivory reflected their macroevolutionary relationships, with P. pinaster having the most divergent metabolome. The concentrations of phenolic metabolites were generally not higher in the attacked trees, which had lower concentrations of terpenes, suggesting that herbivores avoid individuals with high concentrations of terpenes. Our results suggest that macroevolutionary history plays important roles in the metabolomic responses of these pine species to folivory, but plant-insect coevolution probably constrains those responses. Combinations of different evolutionary factors and trade-offs are likely responsible for the different responses of each species to folivory, which is not necessarily exclusively linked to plant-insect coevolution.

  17. Actors and factors in the governance of irregular migration : a comparative analysis of Albanian, Georgian, Ukrainian, Pakistani and Afghani irregular flows to Greece




    Proceedings from the conference "Governing Irregular Migration : States, Actors and Intermediaries", Athens 8-9 July 2015 The loss of over a thousand human lives in the effort to cross the Mediterranean during April 2015 has once again drawn media and political attention to the challenges that the EU is facing in its efforts to govern migration and asylum. However, what seems to be still far from complete is our (the experts and the politicians) understanding of what drives people to put t...

  18. Computing proton dose to irregularly moving targets

    International Nuclear Information System (INIS)

    Phillips, Justin; Gueorguiev, Gueorgui; Grassberger, Clemens; Dowdell, Stephen; Paganetti, Harald; Sharp, Gregory C; Shackleford, James A


    Purpose: While four-dimensional computed tomography (4DCT) and deformable registration can be used to assess the dose delivered to regularly moving targets, there are few methods available for irregularly moving targets. 4DCT captures an idealized waveform, but human respiration during treatment is characterized by gradual baseline shifts and other deviations from a periodic signal. This paper describes a method for computing the dose delivered to irregularly moving targets based on 1D or 3D waveforms captured at the time of delivery. Methods: The procedure uses CT or 4DCT images for dose calculation, and 1D or 3D respiratory waveforms of the target position at time of delivery. Dose volumes are converted from their Cartesian geometry into a beam-specific radiological depth space, parameterized in 2D by the beam aperture, and longitudinally by the radiological depth. In this new frame of reference, the proton doses are translated according to the motion found in the 1D or 3D trajectory. These translated dose volumes are weighted and summed, then transformed back into Cartesian space, yielding an estimate of the dose that includes the effect of the measured breathing motion. The method was validated using a synthetic lung phantom and a single representative patient CT. Simulated 4DCT was generated for the phantom with 2 cm peak-to-peak motion. Results: A passively-scattered proton treatment plan was generated using 6 mm and 5 mm smearing for the phantom and patient plans, respectively. The method was tested without motion, and with two simulated breathing signals: a 2 cm amplitude sinusoid, and a 2 cm amplitude sinusoid with 3 cm linear drift in the phantom. The tumor positions were equally weighted for the patient calculation. Motion-corrected dose was computed based on the mid-ventilation CT image in the phantom and the peak exhale position in the patient. Gamma evaluation was 97.8% without motion, 95.7% for 2 cm sinusoidal motion, 95.7% with 3 cm drift in

  19. Irregular employment amongst migrants in Spanish cities. (United States)

    Sole, C; Ribas, N; Bergalli, V; Parella, S


    This article presents the irregular employment situation of non-European union immigrants in Spanish cities. Foreign labor is remarkable for its heterogeneity in terms of country of origin, demographic characteristics, and the different ways in which immigrants have entered the job market. Legal immigrants tend to concentrate in five different branches of activity, such as domestic service (mostly women), hotel and restaurant industry, agriculture, building and retail trade. Migrants who work in agriculture suffer the worst labor conditions than all other migrants. However, all migrants experience difficulty in obtaining residency and labor permits. Four integration strategies among Moroccan immigrants in Catalonia are discussed and can be viewed as support networks of the immigrants.

  20. Surface Mosaic Synthesis with Irregular Tiles. (United States)

    Hu, Wenchao; Chen, Zhonggui; Pan, Hao; Yu, Yizhou; Grinspun, Eitan; Wang, Wenping


    Mosaics are widely used for surface decoration to produce appealing visual effects. We present a method for synthesizing digital surface mosaics with irregularly shaped tiles, which are a type of tiles often used for mosaics design. Our method employs both continuous optimization and combinatorial optimization to improve tile arrangement. In the continuous optimization step, we iteratively partition the base surface into approximate Voronoi regions of the tiles and optimize the positions and orientations of the tiles to achieve a tight fit. Combination optimization performs tile permutation and replacement to further increase surface coverage and diversify tile selection. The alternative applications of these two optimization steps lead to rich combination of tiles and high surface coverage. We demonstrate the effectiveness of our solution with extensive experiments and comparisons.

  1. Evidence for a continuous, power law, electron density irregularity spectrum (United States)

    Cronyn, W. M.


    The spectral form of the irregularities in electron density that cause interplanetary scintillation (IPS) of small angular diameter radio sources is discussed. The intensity scintillation technique always yields an irregularity scale size, which is of the order of the first Fresnel zone for the wavelength at which the observations are taken. This includes not only the radio wavelength measurements of the structure of the interplanetary medium, but also radio wavelength measurements of the irregularity structure of the ionosphere and interstellar medium, and optical wavelength measurements of the irregularity structure of the atmosphere.

  2. Experimental Study of Irregular Waves on a Gravel Beach (United States)

    Hu, Nai-Ren; Wu, Yun-Ta; Hwung, Hwung-Hweng; Yang, Ray-Yeng


    In the east coast of Taiwan, the sort grain size more belongs to cobble or gravel, which is physically distinct compared to the sandy beach in the west coast of Taiwan. Although gravel beaches can dissipate more of wave energy, gravel beaches were eroded and coastal road were damaged especially during typhoons. The purpose of this study is to investigate the geomorphological response of gravel beach due to irregular waves. This experiment was carry out in a 21m long, 50 cm wide, 70 cm high wave tank at Tainan Hydraulics Laboratory, National Cheng-Kung University, Taiwan. To simulate of the geometry in the east coast of Taiwan, a physical model with 1/36 scale-down was used, in which the seawall was 10cm built upon a 1:10 slope and gravel grains with D50 being 3.87 mm was nourished in front of the seawall. In terms of typhoon-scale wave condition, irregular waves with scale-down conditions were generated for 600 s for each scenarios and, three different water levels with respect to the gravel beach are designed. Application of laser combined with image processing to produce 3D topographic map, the erosion zone and accretion zone would be found. The resulting morphological change of gravel beach will be measured using an integrated laser and image processing tool to have 3D topographic maps. It is expected to have more understanding about under what conditions the gravel coasts suffer the least damage. In particular, the relation between erosion rates of gravel beach, the angle of gravel slope and the length of the plane on the gravel slope will be achieved

  3. ESA' s novel gravitational modeling of irregular planetary bodies (United States)

    Ortega, Guillermo

    A detailed understanding and modeling of the gravitational modeling is required for realistic investigation of the dynamics of orbits close to irregularly shaped bodies. Gravity field modelling up to a certain maximum spherical harmonic degree N involves N2 unkown spherical harmonic coefficients or complex harmonics. The corresponding number of matrix entries reaches till N4 . For missions like CHAMP, GRACE or GOCE, the maximum degree of resolution is 75, 150 and 300 respectively. Therefore, the number of unknowns for a satellite like GOCE will be around 100.000. Since these missions usually fly for a period of time of several years, the number of observations is huge. Hence, gravity field recovery from these missions is a high demanding task. The classical approaches like spherical expansion of the potential lead generally to a high number of coefficients, which reduce the software computational efficiency of the orbit propagation and which have mostly a limited physical meaning. One of the main targets of the activity is the modelling of asteroids, small moons, and cometary bodies. All celestial bodies are irregular by definition. However, the scope of the activity is broad enough as to be able to use the models and the software in quasy-regular bodies as well. Therefore the models and tools could be used for bodies such as the Moon, Mars, Venus, Deimos, Europa, Eros, Mathilda, and Churyumov-Gerasimenko, etc., being these applications relevant for scientific (Rosetta, Bepi Colombo), exploration (Exo-Mars), NEO mitigation (Don Quijote) and Earth observation (GOCE) missions of ESA.

  4. Advances in electron dosimetry of irregular fields; Avances en dosimetria de electrones de campos irregulares

    Energy Technology Data Exchange (ETDEWEB)

    Mendez V, J. [Departamento de Radioterapia, Instituto de Enfermedades Neoplasicas, Avenida Angamos Este 2520, Lima 34 (Peru)


    In this work it is presented an advance in Electron dosimetry of irregular fields for beams emitted by linear accelerators. At present diverse methods exist which are coming to apply in the Radiotherapy centers. In this work it is proposed a method for irregular fields dosimetry. It will be allow to calculate the dose rate absorbed required for evaluating the time for the treatment of cancer patients. Utilizing the results obtained by the dosimetric system, it has been possible to prove the validity of the method describe for 12 MeV energy and for square field 7.5 x 7.5 cm{sup 2} with percentile error less than 1 % . (Author)

  5. Coevolutionary constraints? The environment alters tripartite interaction traits in a legume.

    Directory of Open Access Journals (Sweden)

    Katy D Heath

    Full Text Available Third party species, which interact with one or both partners of a pairwise species interaction, can shift the ecological costs and the evolutionary trajectory of the focal interaction. Shared genes that mediate a host's interactions with multiple partners have the potential to generate evolutionary constraints, making multi-player interactions critical to our understanding of the evolution of key interaction traits. Using a field quantitative genetics approach, we studied phenotypic and genetic correlations among legume traits for rhizobium and herbivore interactions in two light environments. Shifts in plant biomass allocation mediated negative phenotypic correlations between symbiotic nodule number and herbivory in the field, whereas positive genetic covariances suggested shared genetic pathways between nodulation and herbivory response. Trait variance-covariance (G matrices were not equal in sun and shade, but nevertheless responses to independent and correlated selection are expected to be similar in both environments. Interactions between plants and aboveground antagonists might alter the evolutionary potential of traits mediating belowground mutualisms (and vice versa. Thus our understanding of legume-rhizobium genetics and coevolution may be incomplete without a grasp of how these networks overlap with other plant interactions.

  6. Natural convection inside an irregular porous cavity; Conveccao natural no interior de uma cavidade porosa irregular

    Energy Technology Data Exchange (ETDEWEB)

    Beltran, Jorge I. LLagostera; Trevisan, Osvair Vidal [Universidade Estadual de Campinas, SP (Brazil). Faculdade de Engenharia Mecanica. Dept. de Energia


    Natural convection flow induced by heating from below in a irregular porous cavity is investigated numerically. The influence of the modified Rayleigh number and geometric ratios on heat transfer and fluid flow is studied. Global and local Nusselt for Rayleigh numbers covering the range 0 - 1600 and for several geometric ratios. The fluid flow and the temperature field are illustrated by contour maps. (author) 6 refs., 10 figs., 7 tabs.

  7. Regularities and irregularities in order flow data (United States)

    Theissen, Martin; Krause, Sebastian M.; Guhr, Thomas


    We identify and analyze statistical regularities and irregularities in the recent order flow of different NASDAQ stocks, focusing on the positions where orders are placed in the order book. This includes limit orders being placed outside of the spread, inside the spread and (effective) market orders. Based on the pairwise comparison of the order flow of different stocks, we perform a clustering of stocks into groups with similar behavior. This is useful to assess systemic aspects of stock price dynamics. We find that limit order placement inside the spread is strongly determined by the dynamics of the spread size. Most orders, however, arrive outside of the spread. While for some stocks order placement on or next to the quotes is dominating, deeper price levels are more important for other stocks. As market orders are usually adjusted to the quote volume, the impact of market orders depends on the order book structure, which we find to be quite diverse among the analyzed stocks as a result of the way limit order placement takes place.

  8. Irregular Homogeneity Domains in Ternary Intermetallic Systems

    Directory of Open Access Journals (Sweden)

    Jean-Marc Joubert


    Full Text Available Ternary intermetallic A–B–C systems sometimes have unexpected behaviors. The present paper examines situations in which there is a tendency to simultaneously form the compounds ABx, ACx and BCx with the same crystal structure. This causes irregular shapes of the phase homogeneity domains and, from a structural point of view, a complete reversal of site occupancies for the B atom when crossing the homogeneity domain. This work reviews previous studies done in the systems Fe–Nb–Zr, Hf–Mo–Re, Hf–Re–W, Mo–Re–Zr, Re–W–Zr, Cr–Mn–Si, Cr–Mo–Re, and Mo–Ni–Re, and involving the topologically close-packed Laves, χ and σ phases. These systems have been studied using ternary isothermal section determination, DFT calculations, site occupancy measurement using joint X-ray, and neutron diffraction Rietveld refinement. Conclusions are drawn concerning this phenomenon. The paper also reports new experimental or calculated data on Co–Cr–Re and Fe–Nb–Zr systems.

  9. Multiresolution Analysis Adapted to Irregularly Spaced Data

    Directory of Open Access Journals (Sweden)

    Anissa Mokraoui


    Full Text Available This paper investigates the mathematical background of multiresolution analysis in the specific context where the signal is represented by irregularly sampled data at known locations. The study is related to the construction of nested piecewise polynomial multiresolution spaces represented by their corresponding orthonormal bases. Using simple spline basis orthonormalization procedures involves the construction of a large family of orthonormal spline scaling bases defined on consecutive bounded intervals. However, if no more additional conditions than those coming from multiresolution are imposed on each bounded interval, the orthonormal basis is represented by a set of discontinuous scaling functions. The spline wavelet basis also has the same problem. Moreover, the dimension of the corresponding wavelet basis increases with the spline degree. An appropriate orthonormalization procedure of the basic spline space basis, whatever the degree of the spline, allows us to (i provide continuous scaling and wavelet functions, (ii reduce the number of wavelets to only one, and (iii reduce the complexity of the filter bank. Examples of the multiresolution implementations illustrate that the main important features of the traditional multiresolution are also satisfied.

  10. Near-Infrared Spectroscopy of Himalia An Irregular Jovian Satellite (United States)

    Brown, R. H.; Baines, K.; Bellucci, G.; Bibring, J.-P.; Buratti, B.; Capaccioni, F.; Cerroni, P.; Clark, R.; Coradini, A.; Cruikshank, D.


    Spectra of the irregular Jovian satellite Himalia were obtained with the Visual and Infrared Mapping Spectrometer (VIMS) onboard Cassini during the Jupiter Flyby on December 18-19, 2000. These are the first spectral data of an irregular satellite beyond 2.5 microns. Additional information is contained in the original extended abstract.

  11. An investigation into design of fair surfaces over irregular domains ...

    Indian Academy of Sciences (India)

    Design of fair surfaces over irregular domains is a fundamental problem in computer-aided geometric design (CAGD), and has applications in engineering sciences (in aircraft, automobile, ship science etc.). In the design of fair surfaces over irregular domains defined over scattered data, it was widely accepted till recently ...

  12. Decomposing graphs into a constant number of locally irregular subgraphs

    DEFF Research Database (Denmark)

    Bensmail, Julien; Merker, Martin; Thomassen, Carsten


    . This is the first general constant upper bound on the irregular chromatic index of bipartite graphs. Combining this result with Przybyło’s result, we show that χirr′(G)≤328 for every graph G which admits a decomposition into locally irregular subgraphs. Finally, we show that χirr′(G)≤2 for every 16-edge...

  13. Over rough and smooth : Amputee gait on an irregular surface

    NARCIS (Netherlands)

    Curtze, Carolin; Hof, At L.; Postema, Klaas; Otten, Bert

    When negotiating irregular surfaces, the control of dynamic stability is challenged. In this study, we compared the adjustments in stepping behaviour and arm-swing of 18 unilateral transtibial amputees and 17 able-bodied participants when walking on flat and irregular surfaces. Experimental findings

  14. Effect of irregularity on torsional surface waves in an initially ...

    Indian Academy of Sciences (India)

    Effect of irregularity on torsional surface waves in an initially stressed anisotropic porous layer sandwiched between homogeneous and non-homogeneous half- ... Torsional wave; anisotropy; initial stress; irregularity; non-homogeneity ... Department of Applied Mathematics, Indian School of Mines, Dhanbad 826 004, India.

  15. Regularisation of irregular verbs in child English second language ...

    African Journals Online (AJOL)

    Data was collected from the language of English medium preschool children. The study concludes that when the Blocking Principle interferes, children resort to a novel interlanguage rule that regularises irregular verbs. This interlanguage rule applies in a similar way to all irregular verbs, thus children produce utterances ...

  16. Effects of irregularity and anisotropy on the propagation of shear ...

    African Journals Online (AJOL)

    The propagation of shear waves differs between geo-media due to layer's structure and irregularity present in different layers. This paper studies the propagation of shear waves in a monoclinic layer with irregularity lying between two isotropic semiinfinite elastic medium. The displacement in the monoclinic layer is obtained ...

  17. Software support for irregular and loosely synchronous problems (United States)

    Choudhary, A.; Fox, G.; Hiranandani, S.; Kennedy, K.; Koelbel, C.; Ranka, S.; Saltz, J.


    A large class of scientific and engineering applications may be classified as irregular and loosely synchronous from the perspective of parallel processing. We present a partial classification of such problems. This classification has motivated us to enhance FORTRAN D to provide language support for irregular, loosely synchronous problems. We present techniques for parallelization of such problems in the context of FORTRAN D.

  18. What works for irregular migrants in the Netherlands?

    NARCIS (Netherlands)

    M.M. Boone (Miranda); M.H. Kox (Mieke)


    textabstractThis contribution provides an overview of the extent to which rehabilitation instruments and opportunities are accessible for irregular migrants who are serving a criminal sanction in the Netherlands. It shows that irregular migrants are largely excluded from criminal sanctions that have

  19. Co-Evolutionary Mechanisms of Emotional Bursts in Online Social Dynamics and Networks

    Directory of Open Access Journals (Sweden)

    Bosiljka Tadić


    Full Text Available Collective emotional behavior of users is frequently observed on various Web portals; however, its complexity and the role of emotions in the acting mechanisms are still not thoroughly understood. In this work, using the empirical data and agent-based modeling, a parallel analysis is performed of two archetypal systems—Blogs and Internet-Relayed-Chats—both of which maintain self-organized dynamics but not the same communication rules and time scales. The emphasis is on quantifying the collective emotions by means of fractal analysis of the underlying processes as well as topology of social networks, which arise and co-evolve in these stochastic processes. The results reveal that two distinct mechanisms, which are based on different use of emotions (an emotion is characterized by two components, arousal and valence, are intrinsically associated with two classes of emergent social graphs. Their hallmarks are the evolution of communities in accordance with the excess of the negative emotions on popular Blogs, on one side, and smooth spreading of the Bot’s emotional impact over the entire hierarchical network of chats, on the other. Another emphasis of this work is on the understanding of nonextensivity of the emotion dynamics; it was found that, in its own way, each mechanism leads to a reduced phase space of the emotion components when the collective dynamics takes place. That a non-additive entropy describes emotion dynamics, is further confirmed by computing the q-generalized Kolmogorov-Sinai entropy rate in the empirical data of chats as well as in the simulations of interacting emotional agents and Bots.

  20. Decomposing Oriented Graphs into Six Locally Irregular Oriented Graphs

    DEFF Research Database (Denmark)

    Bensmail, Julien; Renault, Gabriel


    An undirected graph G is locally irregular if every two of its adjacent vertices have distinct degrees. We say that G is decomposable into k locally irregular graphs if there exists a partition E1∪E2∪⋯∪Ek of the edge set E(G) such that each Ei induces a locally irregular graph. It was recently...... conjectured by Baudon et al. that every undirected graph admits a decomposition into at most three locally irregular graphs, except for a well-characterized set of indecomposable graphs. We herein consider an oriented version of this conjecture. Namely, can every oriented graph be decomposed into at most...... three locally irregular oriented graphs, i.e. whose adjacent vertices have distinct outdegrees? We start by supporting this conjecture by verifying it for several classes of oriented graphs. We then prove a weaker version of this conjecture. Namely, we prove that every oriented graph can be decomposed...

  1. Unravelling mummies: cryptic diversity, host specificity, trophic and coevolutionary interactions in psyllid - parasitoid food webs. (United States)

    Hall, Aidan A G; Steinbauer, Martin J; Taylor, Gary S; Johnson, Scott N; Cook, James M; Riegler, Markus


    Parasitoids are hyperdiverse and can contain morphologically and functionally cryptic species, making them challenging to study. Parasitoid speciation can arise from specialisation on niches or diverging hosts. However, which process dominates is unclear because cospeciation across multiple parasitoid and host species has rarely been tested. Host specificity and trophic interactions of the parasitoids of psyllids (Hemiptera) remain mostly unknown, but these factors are fundamentally important for understanding of species diversity, and have important applied implications for biological control. We sampled diverse parasitoid communities from eight Eucalyptus-feeding psyllid species in the genera Cardiaspina and Spondyliaspis, and characterised their phylogenetic and trophic relationships using a novel approach that forensically linked emerging parasitoids with the presence of their DNA in post-emergence insect mummies. We also tested whether parasitoids have cospeciated with their psyllid hosts. The parasitoid communities included three Psyllaephagus morphospecies (two primary and, unexpectedly, one heteronomous hyperparasitoid that uses different host species for male and female development), and the hyperparasitoid, Coccidoctonus psyllae. However, the number of genetically delimited Psyllaephagus species was three times higher than the number of recognisable morphospecies, while the hyperparasitoid formed a single generalist species. In spite of this, cophylogenetic analysis revealed unprecedented codivergence of this hyperparasitoid with its primary parasitoid host, suggesting that this single hyperparasitoid species is possibly diverging into host-specific species. Overall, parasitoid and hyperparasitoid diversification was characterised by functional conservation of morphospecies, high host specificity and some host switching between sympatric psyllid hosts. We conclude that host specialisation, host codivergence and host switching are important factors driving

  2. Computational Analysis of Residue Interaction Networks and Coevolutionary Relationships in the Hsp70 Chaperones: A Community-Hopping Model of Allosteric Regulation and Communication.

    Directory of Open Access Journals (Sweden)

    Gabrielle Stetz


    Full Text Available Allosteric interactions in the Hsp70 proteins are linked with their regulatory mechanisms and cellular functions. Despite significant progress in structural and functional characterization of the Hsp70 proteins fundamental questions concerning modularity of the allosteric interaction networks and hierarchy of signaling pathways in the Hsp70 chaperones remained largely unexplored and poorly understood. In this work, we proposed an integrated computational strategy that combined atomistic and coarse-grained simulations with coevolutionary analysis and network modeling of the residue interactions. A novel aspect of this work is the incorporation of dynamic residue correlations and coevolutionary residue dependencies in the construction of allosteric interaction networks and signaling pathways. We found that functional sites involved in allosteric regulation of Hsp70 may be characterized by structural stability, proximity to global hinge centers and local structural environment that is enriched by highly coevolving flexible residues. These specific characteristics may be necessary for regulation of allosteric structural transitions and could distinguish regulatory sites from nonfunctional conserved residues. The observed confluence of dynamics correlations and coevolutionary residue couplings with global networking features may determine modular organization of allosteric interactions and dictate localization of key mediating sites. Community analysis of the residue interaction networks revealed that concerted rearrangements of local interacting modules at the inter-domain interface may be responsible for global structural changes and a population shift in the DnaK chaperone. The inter-domain communities in the Hsp70 structures harbor the majority of regulatory residues involved in allosteric signaling, suggesting that these sites could be integral to the network organization and coordination of structural changes. Using a network-based formalism of

  3. IHY objectives in the African ionospheric irregularities observation campaign (United States)

    Yizengaw, E.; Moldwin, M. B.


    : One of many objectives of IHY is the deployment of networks of small instruments, especially closing the land-based gaps of instruments around the world. One of the regions that have been almost entirely devoid of ground-based instruments is the African continent. Such uneven distribution of ground-based instruments hinders our ability to obtain a global understanding of the equatorial ionosphere. In the African sector, for example, a continuous ground-based observation of the equatorial ionospheric irregularities is not possible due to lack of ground-based instruments, causing many fundamental questions to remain unanswered. Satellite observations indicate the equatorial ionospheric density structures in the African continent respond to space weather effects differently than do other parts of the Earth. For example, in the African equatorial region, satellite observations show that the F-region bubbles are much deeper than the bubbles observed in any other longitudinal sectors, and are very active year round compared with other regions. Observations also show that the bubbles in Africa rises to high altitude (up to 1000+ kilometers) more frequently compared with other longitudes. However, these responses have not been studied in detail by observations from the ground due to the lack of suitable ground-based instrumentation in the region. Thus, the cause of these unique density irregularities in the continent remains a mystery for the scientific community. Therefore, in order to have a better understanding, the scientific communities, using the IHY platform, are now closing the largest land-based gap in ground-based instruments such as GPS receivers and magnetometers. The instrumentation network in African is already developing rapidly with GPS receivers from SCINDA, AMMA, IGS, and AGREES and magnetometers from MAGDAS and AMBER. In addition to new scientific discoveries and advancing space science research in Africa by establishing scientific collaborations

  4. Star Formation Histories of Dwarf Irregular Galaxies (United States)

    Skillman, Evan


    We propose to obtain deep WFPC2 `BVI' color-magnitude diagrams {CMDs} for the dwarf irregular {dI} Local Group galaxies GR 8, Leo A, Pegasus, and Sextans A. In addition to resolved stars, we will use star clusters, and especially any globulars, to probe the history of intense star formation. These data will allow us to map the Pop I and Pop II stellar components, and thereby construct the first detailed star formation histories for non-interacting dI galaxies. Our results will bear on a variety of astrophysical problems, including the evolution of small galaxies, distances in the Local Group, age-metallicity distributions in small galaxies, ages of dIs, and the physics of star formation. The four target galaxies are typical dI systems in terms of luminosity, gas content, and H II region abundance, and represent a range in current star forming activity. They are sufficiently near to allow us to reach to stars at M_V = 0, have 0.1 of the luminosity of the SMC and 0.25 of its oxygen abundance. Unlike the SMC, these dIs are not near giant galaxies. This project will allow the extension of our knowledge of stellar populations in star forming galaxies from the spirals in the Local Group down to its smallest members. We plan to take maximum advantage of the unique data which this project will provide. Our investigator team brings extensive and varied experience in studies of dwarf galaxies, stellar populations, imaging photometry, and stellar evolution to this project.

  5. [Rare blood donors with irregular antibodies]. (United States)

    Milanović, Mirjana Krga; Bujandrić, Nevenka; Knezević, Natasa Milosavljević


    Blood groups are inherited biological characteristics that do not change throughout life in healthy people. Blood groups represent antigens found on the surface of red blood cells. Kell blood group system consists of 31 antigens. Kell antigen (K) is present in 0.2% of the population (the rare blood group). Cellano antigen is present in more than 99% (the high-frequency antigen). These antigens have a distinct ability to cause an immune response in the people after blood transfusion or pregnancy who, otherwise, did not have them before. This paper presents a blood donor with a rare blood group, who was found to have an irregular antibody against red blood cells by indirect antiglobulin test. Further testing determined the specificity of antibody to be anti-Cellano. The detected antibody was found in high titers (1024) with erythrocyte phenotype Kell-Cellano+. The blood donor was found to have a rare blood group KellKell. This donor was excluded from further blood donation. It is difficult to find compatible blood for a person who has developed an antibody to the high-frequency antigen. The donor's family members were tested and Cellano antigen was detected in her husband and child. A potential blood donor was not found among the family members. There was only one blood donor in the Register of blood donors who was compatible in the ABO and Kell blood group system. For the successful management of blood transfusion it is necessary to establish a unified national register of donors of rare blood groups and cooperate with the International Blood Group Reference Laboratory in Bristol with the database that registers donors of rare blood groups from around the world.



    Brijesh Thakur; Sanjay Kaushik; Sanjeev Kishore; Rajnish Kuma; Anil Rajput


    BACKGROUND Blood group plays a vital role in transfusion safety, understanding genetics, inheritance pattern and disease susceptibility. This study is aimed to determine distribution pattern of ABO and Rh blood group, incidence and identification of irregular antibodies among blood donors of Uttarakhand. METHOD ABO/Rh blood grouping was performed by test tube agglutination method (both cell and serum grouping) using antisera A, B and Rh from Tulip and Orthodiagnostics. Do...

  7. Evolution of angiosperm seed disperser mutualisms: the timing of origins and their consequences for coevolutionary interactions between angiosperms and frugivores. (United States)

    Eriksson, Ove


    , and many of the originations of fleshy fruits occurred well after the peak in the early Eocene. (vi) During periods associated with environmental change altering coevolutionary networks and opening of niche space, reciprocal coevolution may result in strong directional selection formative for both fruit and frugivore evolution. Further evidence is needed to test this hypothesis. Based on the abundance of plant lineages with various forms of fleshy fruits, and the diversity of frugivores, it is suggested that periods of rapid coevolution in angiosperms and frugivores occurred numerous times during the 80 million years of angiosperm-frugivore evolution. © 2014 The Authors. Biological Reviews published by John Wiley & Sons Ltd on behalf of Cambridge Philosophical Society.

  8. Irregular antibodies: an assessment of routine prenatal screening. (United States)

    Solola, A; Sibai, B; Mason, J M


    In a review of the antenatal-postnatal records of 6062 patients attending the prenatal clinic at a large university perinatal center during 1980, 8.3% of the pregnant patients seen were Rho(D) negative and 91.7% were Rho(D) positive. Through routine antibody screening of all patients, 115 were found to have irregular antibodies which would otherwise not have been detected. Fifteen of these patients were Rho(D) negative, but they would have been included for antibody screening due to their Rho(D) negative status. Of the remaining 100 Rho(D) positive patients, clinically significant antibodies were observed in six patients; however, no maternal morbidity or hemolytic disease of the newborn was reported. Antecedent maternal risk factors for development of irregular antibodies were not sufficiently selective for predicting outcomes of such pregnancies. Furthermore, the only four patients with irregular antibodies requiring blood transfusion were cross-matched without difficulties. Findings suggest that screening all patients for irregular antibodies cannot be justified due to the prohibitive costs involved. However, because of the racially homogeneous population studied, variations in the frequency of red blood cell genotypes between racial groups, and the irregular pattern of occurrence of irregular antibodies, the authors believe that further studies on the clinical impact and cost-effectiveness of screening all antenatal patients for presence of irregular antibodies are necessary.

  9. Orbital maneuvers around irregular shaped bodies (United States)

    Venditti, Flaviane; Rocco, E. M.; Almeida Prado, A. B.


    Abstract (2,250 Maximum Characters): In the solar system there are many small bodies called asteroids. The large majority of these bodies are located in the asteroid belt, between the orbits of the planets Mars and Jupiter. The Near- Earth Objects, or NEOs, are objects with perihelion below 1.3AU, which include comets and asteroids. The NEOs are considered to have orbits passing close to the Earth’s orbit and, in the case of asteroids, are called Near-Earth Asteroids (NEAs). Among the NEAs there are bodies considered potentially hazardous asteroids (PHAs), whose minimum orbit intersection distance with Earth is 0.05AU and that have absolute magnitude (H) of 22, which would mean an asteroid of at least 110-240 meters, depending on its albedo. One of the major characteristic of the asteroids is the irregular shape, causing the dynamics of orbits around these bodies to be different from a spherical shaped one. The fact that an object is not spherical generates a perturbation on the gravitational field. The disturbing force can be determined considering the shape of the specific body. A satellite orbiting this body would suffer the effects of this perturbation, but knowing the disturbing force, it’s possible to correct and control the orbit according to the desired mission. The polyhedron method is a traditional way to model an asteroid by dividing the object into smaller parts. The data used on this work are composed by a combination of triangular faces. The total disturbing force is a sum of the force on each piece of the model. Therefore, after the simulations are obtained, it’s possible to apply the desired corrections of the perturbation using continuous low thrust in closed loop, making it possible to perform maneuvers near these bodies. One of the important applications of the study shown above is in the ASTER mission, that is under study by INPE and several other Brazilian academic institutions, which goal is to send a spacecraft to an asteroid and then

  10. Punctuated Equilibrium in Statistical Models of Generalized Coevolutionary Resilience: How Sudden Ecosystem Transitions Can Entrain Both Phenotype Expression and Darwinian Selection (United States)

    Wallace, Rodrick; Wallace, Deborah

    We argue that mesoscale ecosystem resilience shifts akin to sudden phase transitions in physical systems can entrain similarly punctuated events of gene expression on more rapid time scales, and, in part through such means, slower changes induced by selection pressure, triggering punctuated equilibrium Darwinian evolutionary transitions on geologic time scales. The approach reduces ecosystem, gene expression, and Darwinian genetic dynamics to a least common denominator of information sources interacting by crosstalk at markedly differing rates. Pettini's 'topological hypothesis', via a homology between information source uncertainty and free energy density, generates a regression-like class of statistical models of sudden coevolutionary phase transition based on the Rate Distortion and Shannon-McMillan Theorems of information theory which links all three levels. A mathematical treatment of Holling's extended keystone hypothesis regarding the particular role of mesoscale phenomena in entraining both slower and faster dynamical structures produces the result. A main theme is the necessity of a cognitive paradigm for gene expression, mirroring I. Cohen's cognitive approach to immune function. Invocation of the necessary conditions imposed by the asymptotic limit theorems of communication theory enables us to penetrate one layer more deeply before needing to impose an empirically-derived phenomenological system of 'Onsager relation' recursive coevolutionary stochastic differential equations. Extending the development to second order via a large deviations argument permits modeling the influence of human cultural structures on ecosystems as 'farming'.

  11. Justice: A Problem for Military Ethics during Irregular War

    National Research Council Canada - National Science Library

    Bauer, John W


    ... is?" or "Justice according to whom?" The relative nature of the term "justice" creates a problem for military ethics, particularly when soldiers try to determine what actions are morally acceptable when they are engaged in irregular warfare...

  12. Drug Intoxicated Irregular Fighters: Complications, Dangers, and Responses

    National Research Council Canada - National Science Library

    Kan, Paul R


    .... Drug consumption in contemporary wars has coincided with the use of child soldiers, has led to increased unpredictability among irregular fighters, provided the conditions for the breakdown of social...

  13. Role of parametric decay instabilities in generating ionospheric irregularities

    International Nuclear Information System (INIS)

    Kuo, S.P.; Cheo, B.R.; Lee, M.C.


    We show that purely growing instabilities driven by the saturation spectrum of parametric decay instabilities can produce a broad spectrum of ionospheric irregularities. The threshold field Vertical BarE/sub th/Vertical Bar of the instabilities decreases with the scale lengths lambda of the ionospheric irregularities as Vertical BarE/sub th/Vertical Barproportionallambda -2 in the small-scale range ( -2 with scale lengths larger than a few kilometers. The excitation of kilometer-scale irregularities is strictly restricted by the instabilities themselves and by the spatial inhomogeneity of the medium. These results are drawn from the analyses of four-wave interaction. Ion-neutral collisions impose no net effect on the instabilities when the excited ionospheric irregularities have a field-aligned nature

  14. Irregular Warfare: Impact on Future Professional Military Education

    National Research Council Canada - National Science Library

    Paschal, David G


    ... to operate effectively in an irregular warfare environment. The utility of a decisive war between nation states continues to decline and will eventually reach critical mass based upon the extreme imbalance of military power and a U.S. monopoly...

  15. Propagation of shear waves in viscoelastic medium at irregular boundaries (United States)

    Chattopadhyay, Amares; Gupta, Shishir; Sharma, Vikash; Kumari, Pato


    The aim of the paper is to study the shear wave propagation in a viscoelastic layer over a semi-infinite viscoelastic half space due to irregularity in the viscoelastic layer. It is of great interest to study the propaga-tion of shear waves in the assumed medium having a non planar boundary due to its similarity to most of the real situations. The perturbation method is applied to find the displacement field. The effect of complex wave number on dissipation factor is analysed. Finally, as an application, the result obtained has been used to get the reflected field in viscoelastic layer when the shear wave is incident on an irregular boundary in the shape of parabolic irregularity as well as triangular notch. It is observed that the amplitude of this reflected wave decreases with increasing length of the notch, and increases with increasing depth of the irregularity.

  16. Irregular Warfare: Special Operations Joint Professional Military Education Transformation

    National Research Council Canada - National Science Library

    Cannady, Bryan H


    ... on today's battlefront in Afghanistan and Iraq and in the Global War on Terrorism (GWOT). At the forefront of the GWOT and irregular warfare are the United States Special Operations Command (USSOCOM...

  17. Irregular Techniques for Controlling Under-Governed Space

    National Research Council Canada - National Science Library

    Coburn, Matthew D


    .... This study uses the cases of Hezbollah in Lebanon and the Taliban in Afghanistan to determine how irregular forces, with external support, can establish political control of undergoverned space...

  18. Design Optimization of Irregular Cellular Structure for Additive Manufacturing (United States)

    Song, Guo-Hua; Jing, Shi-Kai; Zhao, Fang-Lei; Wang, Ye-Dong; Xing, Hao; Zhou, Jing-Tao


    Irregularcellular structurehas great potential to be considered in light-weight design field. However, the research on optimizing irregular cellular structures has not yet been reporteddue to the difficulties in their modeling technology. Based on the variable density topology optimization theory, an efficient method for optimizing the topology of irregular cellular structures fabricated through additive manufacturing processes is proposed. The proposed method utilizes tangent circles to automatically generate the main outline of irregular cellular structure. The topological layoutof each cellstructure is optimized using the relative density informationobtained from the proposed modified SIMP method. A mapping relationship between cell structure and relative densityelement is builtto determine the diameter of each cell structure. The results show that the irregular cellular structure can be optimized with the proposed method. The results of simulation and experimental test are similar for irregular cellular structure, which indicate that the maximum deformation value obtained using the modified Solid Isotropic Microstructures with Penalization (SIMP) approach is lower 5.4×10-5 mm than that using the SIMP approach under the same under the same external load. The proposed research provides the instruction to design the other irregular cellular structure.

  19. Effect of irregular interproximal dental restorations on periodontal status

    Directory of Open Access Journals (Sweden)

    Matvijenko Vladimir B.


    Full Text Available Introduction. Research of effects that irregular interproximal dental restoration have on supporting structures of the teeth and examination of evolution and course of changes in tissue structure is quite a poorly studied topic. Aim of this study is to examine and assess clinical and radiological changes in periodontal tissue caused by irregular interproximal dental restoration in particular group of patients with different age and sex. Methods. Irregularities which were assesed in this study are divided into two groups: a gap (cracks occurring between dental restorations and the gingival walls in Class II cavities, b prominence of dental fillings out of the teeth anatomical sphere, resulting with the positive step in gum third of tooth in Class II cavities. The study was based on whether in the particular forms of irregularities of the dental restorations are differences in the degree of change in the periodontal tissue, depending on the material from which the restoration is made, and the materials used were composite fillings and amalgams. Results of this study show that irregular dental fillings significantly affect the inflammatory response in periodontal tissue. Irregularities in the form of unfilled space cause major changes in periodontal tissue. Composite fillings cause a higher degree of inflammation in relation to amalgam fillings. Conclusion. Improper tooth fillings cause periodontal tissue damages.

  20. The structure of plasma density irregularities in the interplanetary medium

    International Nuclear Information System (INIS)

    Singleton, D.G.


    Observations of the scintillation of sources 3C273 and 3C279 at 2292 MHz are described. The interpretation of the scintillation in terms of the structure of the plasma-density irregularities in the interplanetary medium is discussed. Scintillation index measurements obtained during these observations are combined with similar measurements at other frequencies reported in the literature. The resulting variation of the scintillation-index and observing-frequency product with source elongation is interpreted in terms of irregularities with a spatial spectrum of electron density which is of power law form. This result is reinforced by an analysis of the spectra of the observed scintillations. Several tests are applied to both the Fourier and Bessel spectra which illustrate conclusively that the irregularity spatial spectrum is of power law form, rather than the Gaussian form suggested by some workers. The spectra also show that the irregularities are isotopic within 0.2 AU of the sun, while there is some evidence that a degree of elongation normal to the direction of the motion of the irregularities may develop at slightly greater solar distances. The irregularity velocities determined are consistent with solar wind velocities. (author)

  1. Equatorial Ionospheric Irregularities Study from ROCSAT Data (United States)


    Earthquake . Signals in a time-series are not always stationary or linear. The best way to analyze such data is, to our best understanding, using the...intrinsic mode function) each has a perfect Hilbert transform and exhibits distinctive oscillation frequencies . Using the HHT method to analyze...the radio beacon data, we can find some hidden oscillations at some particular frequency in the signals that is not related to the density

  2. Studies of small scale irregularities in the cusp ionosphere using sounding rockets: recent results (United States)

    Spicher, A.; Ilyasov, A. A.; Miloch, W. J.; Chernyshov, A. A.; Moen, J.; Clausen, L. B. N.; Saito, Y.


    Plasma irregularities occurring over many scale sizes are common in the ionosphere. Understanding and characterizing the phenomena responsible for these irregularities is not only important from a theoretical point of view, but also in the context of space weather, as the irregularities can disturb HF communication and Global Navigation Satellite Systems signals. Overall, research about the small-scale turbulence has not progressed as fast for polar regions as for the equatorial ones, and for the high latitude ionosphere there is still no agreement nor detailed explanation regarding the formation of irregularities. To investigate plasma structuring at small scales in the cusp ionosphere, we use high resolution measurements from the Investigation of Cusp Irregularities (ICI) sounding rockets, and investigate a region associated with density enhancements and a region characterized by flow shears. Using the ICI-2 electron density data, we give further evidence of the importance of the gradient drift instability for plasma structuring inside the polar cap. In particular, using higher-order statistics, we provide new insights into the nature of the resulting plasma structures and show that they are characterized by intermittency. Using the ICI-3 data, we show that the entire region associated with a reversed flow event (RFE), with the presence of meter-scale irregularities, several flow shears and particle precipitation, is highly structured. By performing a numerical stability analysis, we show that the inhomogeneous-energy-density-driven instability (IEDDI) may be active in relation to RFEs at the rocket's altitude. In particular, we show that the presence of particle precipitation decreases the growth rates of IEDDI and, using a Local Intermittency Measure, we observe a correlation between IEDDI growth rates and electric field fluctuations over several scales. These findings support the view that large-scale inhomogeneities may provide a background for the

  3. Geostatistical regularization operators for geophysical inverse problems on irregular meshes (United States)

    Jordi, C.; Doetsch, J.; Günther, T.; Schmelzbach, C.; Robertsson, J. OA


    Irregular meshes allow to include complicated subsurface structures into geophysical modelling and inverse problems. The non-uniqueness of these inverse problems requires appropriate regularization that can incorporate a priori information. However, defining regularization operators for irregular discretizations is not trivial. Different schemes for calculating smoothness operators on irregular meshes have been proposed. In contrast to classical regularization constraints that are only defined using the nearest neighbours of a cell, geostatistical operators include a larger neighbourhood around a particular cell. A correlation model defines the extent of the neighbourhood and allows to incorporate information about geological structures. We propose an approach to calculate geostatistical operators for inverse problems on irregular meshes by eigendecomposition of a covariance matrix that contains the a priori geological information. Using our approach, the calculation of the operator matrix becomes tractable for 3-D inverse problems on irregular meshes. We tested the performance of the geostatistical regularization operators and compared them against the results of anisotropic smoothing in inversions of 2-D surface synthetic electrical resistivity tomography (ERT) data as well as in the inversion of a realistic 3-D cross-well synthetic ERT scenario. The inversions of 2-D ERT and seismic traveltime field data with geostatistical regularization provide results that are in good accordance with the expected geology and thus facilitate their interpretation. In particular, for layered structures the geostatistical regularization provides geologically more plausible results compared to the anisotropic smoothness constraints.

  4. Investigation of rail irregularity effects on wheel/rail dynamic force in slab track: Comparison of two and three dimensional models (United States)

    Sadeghi, Javad; Khajehdezfuly, Amin; Esmaeili, Morteza; Poorveis, Davood


    Rail irregularity is one of the most significant load amplification factors in railway track systems. In this paper, the capability and effectiveness of the two main railway slab tracks modeling techniques in prediction of the influences of rail irregularities on the Wheel/Rail Dynamic Force (WRDF) were investigated. For this purpose, two 2D and 3D numerical models of vehicle/discontinuous slab track interaction were developed. The validation of the numerical models was made by comparing the results of the models with those obtained from comprehensive field tests carried out in this research. The effects of the harmonic and non-harmonic rail irregularities on the WRDF obtained from 3D and 2D models were investigated. The results indicate that the difference between WRDF obtained from 2D and 3D models is negligible when the irregularities on the right and left rails are the same. However, as the difference between irregularities of the right and left rails increases, the results obtained from 2D and 3D models are considerably different. The results indicate that 2D models have limitations in prediction of WRDF; that is, a 3D modeling technique is required to predict WRDF when there is uneven or non-harmonic irregularity with large amplitudes. The size and extent of the influences of rail irregularities on the wheel/rail forces were discussed leading to provide a better understanding of the rail-wheel contact behavior and the required techniques for predicting WRDF.

  5. Natural selection drives the fine-scale divergence of a coevolutionary arms race involving a long-mouthed weevil and its obligate host plant

    Directory of Open Access Journals (Sweden)

    Toju Hirokazu


    Full Text Available Abstract Background One of the major recent advances in evolutionary biology is the recognition that evolutionary interactions between species are substantially differentiated among geographic populations. To date, several authors have revealed natural selection pressures mediating the geographically-divergent processes of coevolution. How local, then, is the geographic structuring of natural selection in coevolutionary systems? Results I examined the spatial scale of a "geographic selection mosaic," focusing on a system involving a seed-predatory insect, the camellia weevil (Curculio camelliae, and its host plant, the Japanese camellia (Camellia japonica. In this system, female weevils excavate camellia fruits with their extremely-long mouthparts to lay eggs into seeds, while camellia seeds are protected by thick pericarps. Quantitative evaluation of natural selection demonstrated that thicker camellia pericarps are significantly favored in some, but not all, populations within a small island (Yakushima Island, Japan; diameter ca. 30 km. At the extreme, camellia populations separated by only several kilometers were subject to different selection pressures. Interestingly, in a population with the thickest pericarps, camellia individuals with intermediate pericarp thickness had relatively high fitness when the potential costs of producing thick pericarps were considered. Also importantly, some parameters of the weevil - camellia interaction such as the severity of seed infestation showed clines along temperature, suggesting the effects of climate on the fine-scale geographic differentiation of the coevolutionary processes. Conclusion These results show that natural selection can drive the geographic differentiation of interspecific interactions at surprisingly small spatial scales. Future studies should reveal the evolutionary/ecological outcomes of the "fine scale geographic mosaics" in biological communities.


    Energy Technology Data Exchange (ETDEWEB)

    Grav, T. [Planetary Science Institute, Tucson, AZ 85719 (United States); Bauer, J. M.; Mainzer, A. K.; Masiero, J. R.; Sonnett, S.; Kramer, E. [Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA 91109 (United States); Nugent, C. R.; Cutri, R. M., E-mail: [Infrared Processing and Analysis Center, California Institute of Technology, Pasadena, CA 91125 (United States)


    We present thermal model fits for 11 Jovian and 3 Saturnian irregular satellites based on measurements from the WISE/NEOWISE data set. Our fits confirm spacecraft-measured diameters for the objects with in situ observations (Himalia and Phoebe) and provide diameters and albedo for 12 previously unmeasured objects, 10 Jovian and 2 Saturnian irregular satellites. The best-fit thermal model beaming parameters are comparable to what is observed for other small bodies in the outer solar system, while the visible, W1, and W2 albedos trace the taxonomic classifications previously established in the literature. Reflectance properties for the irregular satellites measured are similar to the Jovian Trojan and Hilda Populations, implying common origins.

  7. Measurement of Dynamic Friction Coefficient on the Irregular Free Surface

    International Nuclear Information System (INIS)

    Yeom, S. H.; Seo, K. S.; Lee, J. H.; Lee, K. H.


    A spent fuel storage cask must be estimated for a structural integrity when an earthquake occurs because it freely stands on ground surface without a restriction condition. Usually the integrity estimation for a seismic load is performed by a FEM analysis, the friction coefficient for a standing surface is an important parameter in seismic analysis when a sliding happens. When a storage cask is placed on an irregular ground surface, measuring a friction coefficient of an irregular surface is very difficult because the friction coefficient is affected by the surface condition. In this research, dynamic friction coefficients on the irregular surfaces between a concrete cylinder block and a flat concrete slab are measured with two methods by one direction actuator

  8. Track Irregularity Time Series Analysis and Trend Forecasting

    Directory of Open Access Journals (Sweden)

    Jia Chaolong


    Full Text Available The combination of linear and nonlinear methods is widely used in the prediction of time series data. This paper analyzes track irregularity time series data by using gray incidence degree models and methods of data transformation, trying to find the connotative relationship between the time series data. In this paper, GM (1,1 is based on first-order, single variable linear differential equations; after an adaptive improvement and error correction, it is used to predict the long-term changing trend of track irregularity at a fixed measuring point; the stochastic linear AR, Kalman filtering model, and artificial neural network model are applied to predict the short-term changing trend of track irregularity at unit section. Both long-term and short-term changes prove that the model is effective and can achieve the expected accuracy.

  9. Exploring Manycore Multinode Systems for Irregular Applications with FPGA Prototyping

    Energy Technology Data Exchange (ETDEWEB)

    Ceriani, Marco; Palermo, Gianluca; Secchi, Simone; Tumeo, Antonino; Villa, Oreste


    We present a prototype of a multi-core architecture implemented on FPGA, designed to enable efficient execution of irregular applications on distributed shared memory machines, while maintaining high performance on regular workloads. The architecture is composed of off-the-shelf soft-core cores, local interconnection and memory interface, integrated with custom components that optimize it for irregular applications. It relies on three key elements: a global address space, multithreading, and fine-grained synchronization. Global addresses are scrambled to reduce the formation of network hot-spots, while the latency of the transactions is covered by integrating an hardware scheduler within the custom load/store buffers to take advantage from the availability of multiple executions threads, increasing the efficiency in a transparent way to the application. We evaluated a dual node system irregular kernels showing scalability in the number of cores and threads.

  10. Irregular Shaped Building Design Optimization with Building Information Modelling

    Directory of Open Access Journals (Sweden)

    Lee Xia Sheng


    Full Text Available This research is to recognise the function of Building Information Modelling (BIM in design optimization for irregular shaped buildings. The study focuses on a conceptual irregular shaped “twisted” building design similar to some existing sculpture-like architectures. Form and function are the two most important aspects of new buildings, which are becoming more sophisticated as parts of equally sophisticated “systems” that we are living in. Nowadays, it is common to have irregular shaped or sculpture-like buildings which are very different when compared to regular buildings. Construction industry stakeholders are facing stiff challenges in many aspects such as buildability, cost effectiveness, delivery time and facility management when dealing with irregular shaped building projects. Building Information Modelling (BIM is being utilized to enable architects, engineers and constructors to gain improved visualization for irregular shaped buildings; this has a purpose of identifying critical issues before initiating physical construction work. In this study, three variations of design options differing in rotating angle: 30 degrees, 60 degrees and 90 degrees are created to conduct quantifiable comparisons. Discussions are focused on three major aspects including structural planning, usable building space, and structural constructability. This research concludes that Building Information Modelling is instrumental in facilitating design optimization for irregular shaped building. In the process of comparing different design variations, instead of just giving “yes or no” type of response, stakeholders can now easily visualize, evaluate and decide to achieve the right balance based on their own criteria. Therefore, construction project stakeholders are empowered with superior evaluation and decision making capability.

  11. The new view of the irregular planetary satellite systems (United States)

    Petit, J.-M.; Gladman, B.; Holman, M.; Grav, T.; Kavelaars, J. J.; Nicholson, P.


    The giant planets in the Solar System each have two groups of satellites. The regular satellites move along nearly circular orbits in the planet's orbital plane, revolving about it in the same sense as the planet spins. In contrast, the so-called irregular satellites are generally smaller in size and are characterized by large orbits with significant eccentricity, inclination or both. The differences in their characteristics suggest that the regular and irregular satellites formed by different mechanisms. The regular satellites have most certainly formed in an accretion disk extending out to tens of planetary radii, like miniature Solar Systems. Irregular satellites, on the contrary, are believed to be planetesimals captured during the final stages of the planet's formation. Before 1997, the irregular satellite inventories of the gas giants where pourly known (Jupiter: 8, Saturn: 1, Uranus: 2, Neptune: 2). Since then, our team have been conducting a series of systematic and complete searches around the giant planets, discovering 12 confirmed satellites around Saturn, 6 around Uranus and 3 around Neptune plus a handfull of candidates. Sheppard et al. have identifyed 11 new irregular satellites around Jupiter while searching a small fraction of its stable region. These discoveries yield insights into the capture process of the satellites. Our team's tracking efforts have shown that the orbits of the Saturnian and Uranian irregular satellites fall into 'groups' in orbital space, ruling out independent capture and indicating that most of the moons we see today are the `children' of larger bodies that were captured long ago and then collisionally fragmented during the lifetime of the solar system.

  12. Deterministic Approach to Detect Heart Sound Irregularities

    Directory of Open Access Journals (Sweden)

    Richard Mengko


    Full Text Available A new method to detect heart sound that does not require machine learning is proposed. The heart sound is a time series event which is generated by the heart mechanical system. From the analysis of heart sound S-transform and the understanding of how heart works, it can be deducted that each heart sound component has unique properties in terms of timing, frequency, and amplitude. Based on these facts, a deterministic method can be designed to identify each heart sound components. The recorded heart sound then can be printed with each component correctly labeled. This greatly help the physician to diagnose the heart problem. The result shows that most known heart sounds were successfully detected. There are some murmur cases where the detection failed. This can be improved by adding more heuristics including setting some initial parameters such as noise threshold accurately, taking into account the recording equipment and also the environmental condition. It is expected that this method can be integrated into an electronic stethoscope biomedical system.

  13. Active Absorption of Irregular Gravity Waves in BEM-Models

    DEFF Research Database (Denmark)

    Brorsen, Michael; Frigaard, Peter


    The boundary element method is applied to the computation of irregular gravity waves. The boundary conditions at the open boundaries are obtained by a digital filtering technique, where the surface elevations in front of the open boundary are filtered numerically yielding the velocity to be presc......The boundary element method is applied to the computation of irregular gravity waves. The boundary conditions at the open boundaries are obtained by a digital filtering technique, where the surface elevations in front of the open boundary are filtered numerically yielding the velocity...

  14. General Lines of Disregard for the Legal Personality on Irregular Dissolution the Company

    Directory of Open Access Journals (Sweden)

    Fábio Augusto Barcelos Moreira Corrêa


    Full Text Available This article will analyze the Institute of disregard for the legal personality in situations involving irregular dissolution the limited liability company, in light of the jurisprudence of the Superior Court Tribunal. We highlight the impact that new code of Civil procedure will provide for analysis to safeguard the autonomy of assets of the legal person, as well as the guarantee of due process and of ample defense, directly impacting on business law. The analysis aims to contribute to the understanding of the Institute, and the systematic procedure. Adopting the dialectical methodology and criticism.

  15. Elastic buckling analysis of corroded stiffened plates with irregular ...

    Indian Academy of Sciences (India)

    reduced by as much as 12% for the interaction of plate-web-torsional buckling mode, and by 2% for column buckling. Keywords. Corrosion; irregular surfaces; stiffened panel; interaction of buckling modes. 1. Introduction. Stiffened plate, where thin plate stiffened with welded longitudinal stiffeners and transverse.

  16. Irregular blocks, N = 2 gauge theory and Mathieu system (United States)

    Piatek, M. R.; Pietrykowski, A. R.


    The Alday-Gayotto-Tachikawa (AGT) conjecture relates 4d N = 2, SU(2) SYM theories with Nf matter hypermultiplets to 2d CFT. In case of pure 4d N = 2, SU(2) SYM there is a corresponding irregular conformal block in 2d CFT. The AGT correspondence may be extended within a certain limit (the Nekrasov-Shataschvili limit) to the correspondence between an effective twisted superpotentials of 2d N = 2 SUSY and the Zamolodchikov's “classical” conformal blocks. When narrowed to the pure 4d N = 2 SYM case its limit is related to an irregular classical conformal block. It will be shown that according to the triple correspondence (2dCFT/Gauge/Bethe - c.f. Piatek's talk) the irregular classical conformal block yields spectrum of Mathieu operator. The latter can be obtained as a “classical” limit of the null vector decoupling equation for three-point degenerate irregular block. It will also be shown that the Mathieu spectrum can be also obtained from the limit of the pure gauge theory as a solution of the saddle point equation as well as from the Bohr-Sommerfeld quantization of the Seiberg-Witten theory.

  17. Size and Albedo of Irregular Saturnian Satellites from Spitzer Observations

    NARCIS (Netherlands)

    Mueller, Michael; Grav, T.; Trilling, D.; Stansberry, J.; Sykes, M.


    Using MIPS onboard the Spitzer Space Telescope, we observed the thermal emission (24 and, for some targets, 70 um) of eight irregular satellites of Saturn: Albiorix, Siarnaq, Paaliaq, Kiviuq, Ijiraq, Tarvos, Erriapus, and Ymir. We determined the size and albedo of all targets. An analysis of

  18. Effect of election irregularities on socio–economic development of ...

    African Journals Online (AJOL)

    Since the fourth Republic there have been trends of bad leadership in the State resulting from election irregularities committed that produce leaders in the State. The nature, extent and magnitude of rigging associated with elections in this state are posing a serious threat to the state quest for stable socioeconomic ...

  19. Effect of irregularity on torsional surface waves in an initially ...

    Indian Academy of Sciences (India)

    The Earth is considered as an initially stressed body with a layered ... Keywords. Torsional wave; anisotropy; initial stress; irregularity; non-homogeneity. J. Earth Syst. Sci., DOI 10.1007/s12040-016-0689-7, 125, No. 4, June 2016, pp. 885–895 ...... wave dispersion in a finitely prestrained hollow sandwich circular cylinder; J.

  20. Robust Fusion of Irregularly Sampled Data Using Adaptive Normalized Convolution

    NARCIS (Netherlands)

    Pham, T.Q.; Van Vliet, L.J.; Schutte, K.


    We present a novel algorithm for image fusion from irregularly sampled data. The method is based on the framework of normalized convolution (NC), in which the local signal is approximated through a projection onto a subspace. The use of polynomial basis functions in this paper makes NC equivalent to

  1. Spectral element method for wave propagation on irregular domains

    Indian Academy of Sciences (India)

    A spectral element approximation of acoustic propagation problems combined with a new mapping method on irregular domains is proposed. Following this method, the Gauss–Lobatto–Chebyshev nodes in the standard space are applied to the spectral element method (SEM). The nodes in the physical space are ...

  2. Spectral element method for wave propagation on irregular domains

    Indian Academy of Sciences (India)

    Yan Hui Geng


    Mar 14, 2018 ... A spectral element approximation of acoustic propagation problems combined with a new mapping method on irregular ... Spectral element method; curved quadrilateral element; isoparametric element; Chebyshev polynomial ... overcome this problem, such as meshless local strong form method [9], the ...


    Directory of Open Access Journals (Sweden)

    A. A. Ketkovich


    Full Text Available The mode of functioning of laser profilometer of the irregular shape items which is urged to replace widely spread at present moment contact measuring devices is described in the article. The main data on the device construction, software support and technical characteristics of the sample being approbated at one of the machinebuilding works are given.

  4. Runtime buffer management to improve the performance in irregular ...

    Indian Academy of Sciences (India)

    ... Refresher Courses · Symposia · Live Streaming. Home; Journals; Sadhana; Volume 40; Issue 4. Runtime buffer management to improve the performance in irregular Network-on-Chip architecture. Umamaheswari S Meganathan D Raja Paul Perinbam J. Electrical and Computer Sciences Volume 40 Issue 4 June 2015 pp ...

  5. Wheel-rail interaction at short-wave irregularities

    NARCIS (Netherlands)

    Steenbergen, M.J.M.M.


    Short-wave irregularities in the wheel-rail interface are at the basis of track and vehicle damage and deterioration. On the short term, they result into high dynamic train-track interaction forces and a high energy input into the system that must be dissipated in the different system components or

  6. Irregularly-shaped school attendance zones and racial integration. (United States)

    Saporito, Salvatore


    This paper investigates how much the geographic shapes of school attendance zones within urban school districts are associated with levels of attendance zone racial segregation (while holding constant levels of residential segregation). Based on an analysis of 304 school districts, findings show that more irregularly-shaped school attendance zones are correlated with lower levels of racial segregation in attendance zones after accounting for residential segregation. In fact, not one school district contains both highly irregularly-shaped attendance zones and unusually high levels of attendance zone racial segregation-although there are several school districts with irregularly-shaped zones and unusually high levels of racial integration. These findings undermine recent claims that irregularly-shaped attendance zones generally serve to segregate students by race. In addition to these empirical findings, this paper introduces a variation of the spatial information theory segregation index H˜ that is useful for predicting segregation in school attendance zones and other types of geographic boundaries containing roughly equal populations. Copyright © 2016 Elsevier Inc. All rights reserved.

  7. On project scheduling with irregular starting time costs

    NARCIS (Netherlands)

    Möhring, Rolf H.; Schulz, Andreas S.; Stork, Frederik; Uetz, Marc Jochen

    Maniezzo and Mingozzi (Oper. Res. Lett. 25 (1999) 175–182) study a project scheduling problem with irregular starting time costs. Starting from the assumption that its computational complexity status is open, they develop a branch-and-bound procedure and they identify special cases that are solvable

  8. Endo-reduplication and irregular division lead to genome ...

    Indian Academy of Sciences (India)

    Table of contents. Endo-reduplication and irregular division lead to genome heterogeneity in Entamoeba histolytica · Slide 2 · Slide 3 · Differences between a mitotic cycle and endo-reduplicating cycle · Heterogeneity of genome content is observed in cells arrested by serum starvation followed by serum addition · Slide 6.

  9. Effect of irregularity and inhomogenity on the propagation of love ...

    African Journals Online (AJOL)

    Dispersion equation for Love waves in a fluid-saturated porous isotropic layer over a semi-infinite non homogene-ous elastic medium with half-space rectangular irregularity was derived by perturbation technique and Fourier transformation. Analysis of the dispersion equation indicated that the phase velocity was strongly ...

  10. The regularized monotonicity method: detecting irregular indefinite inclusions

    DEFF Research Database (Denmark)

    Garde, Henrik; Staboulis, Stratos


    inclusions, where the conductivity distribution has both more and less conductive parts relative to the background conductivity; one such method is the monotonicity method of Harrach, Seo, and Ullrich. We formulate the method for irregular indefinite inclusions, meaning that we make no regularity assumptions...

  11. Modeling irregularly spaced residual series as a continuous stochastic process

    NARCIS (Netherlands)

    Von Asmuth, J.R.; Bierkens, M.F.P.


    In this paper, the background and functioning of a simple but effective continuous time approach for modeling irregularly spaced residual series is presented. The basic equations were published earlier by von Asmuth et al. (2002), who used them as part of a continuous time transfer function noise

  12. Irregular Migration and Vulnerability to HIV&AIDS: Some ...

    African Journals Online (AJOL)

    Mobile populations are at very high risk of HIV infection. At the same time, they can be catalysts in its spread. Migration from Matabeleland region in. Zimbabwe to South Africa has several features that increase this dual disposition of those involved. These features include the largely irregular nature of migration, ...

  13. Runtime buffer management to improve the performance in irregular ...

    Indian Academy of Sciences (India)

    Runtime buffer management in irregular NoC architecture. 1119 information between routers. As the configuration registers in each router stores fault details, this algorithm can tolerate multiple broken links. NoCs in MPSoC architecture may have different communication bandwidth under different applications. To use a ...

  14. Runtime buffer management to improve the performance in irregular ...

    Indian Academy of Sciences (India)

    S¯adhan¯a Vol. 40, Part 4, June 2015, pp. 1117–1137. c Indian Academy of Sciences. Runtime buffer management to improve the performance in irregular Network-on-Chip architecture. UMAMAHESWARI S1,∗, MEGANATHAN D2 and. RAJA PAUL PERINBAM J3. 1Department of Information Technology, Anna University, ...

  15. Characteristics of low latitude ionospheric E-region irregularities ...

    Indian Academy of Sciences (India)

    154°E, dip angle = 37.3°, sub-ionospheric dip = 34°) have been analyzed to study the behaviour of ionospheric E-region irregularities during the active solar and magnetic periods. The autocorrelation functions, power spectral densities, signal de-correlation times are computed to study the temporal features of ionospheric ...

  16. Edge-partitioning graphs into regular and locally irregular components

    DEFF Research Database (Denmark)

    Bensmail, Julien; Stevens, Brett


    -partition into χ'irr(G) classes, each of which induces a locally irregular graph. In particular, they conjectured that χ'irr(G) ≤3 for every G, unless G belongs to a well-characterized family of non-decomposable graphs. This conjecture is far from being settled, as notably (1) no constant upper bound on χ...

  17. Classical limit of irregular blocks and Mathieu functions (United States)

    Piątek, Marcin; Pietrykowski, Artur R.


    The Nekrasov-Shatashvili limit of the N=2 SU(2) pure gauge (Ω-deformed) super Yang-Mills theory encodes the information about the spectrum of the Mathieu operator. On the other hand, the Mathieu equation emerges entirely within the frame of two-dimensional conformal field theory (2 d CFT) as the classical limit of the null vector decoupling equation for some degenerate irregular block. Therefore, it seems to be possible to investigate the spectrum of the Mathieu operator employing the techniques of 2 d CFT. To exploit this strategy, a full correspondence between the Mathieu equation and its realization within 2 d CFT has to be established. In our previous paper [1], we have found that the expression of the Mathieu eigenvalue given in terms of the classical irregular block exactly coincides with the well known weak coupling expansion of this eigenvalue in the case in which the auxiliary parameter is the noninteger Floquet exponent. In the present work we verify that the formula for the corresponding eigenfunction obtained from the irregular block reproduces the so-called Mathieu exponent from which the noninteger order elliptic cosine and sine functions may be constructed. The derivation of the Mathieu equation within the formalism of 2 d CFT is based on conjectures concerning the asymptotic behaviour of irregular blocks in the classical limit. A proof of these hypotheses is sketched. Finally, we speculate on how it could be possible to use the methods of 2 d CFT in order to get from the irregular block the eigenvalues of the Mathieu operator in other regions of the coupling constant.

  18. Classical irregular block, = 2 pure gauge theory and Mathieu equation (United States)

    Piątek, Marcin; Pietrykowski, Artur R.


    Combining the semiclassical/Nekrasov-Shatashvili limit of the AGT conjecture and the Bethe/gauge correspondence results in a triple correspondence which identifies classical conformal blocks with twisted superpotentials and then with Yang-Yang functions. In this paper the triple correspondence is studied in the simplest, yet not completely understood case of pure SU(2) super-Yang-Mills gauge theory. A missing element of that correspondence is identified with the classical irregular block. Explicit tests provide a convincing evidence that such a function exists. In particular, it has been shown that the classical irregular block can be recovered from classical blocks on the torus and sphere in suitably defined decoupling limits of classical external conformal weights. These limits are "classical analogues" of known decoupling limits for corresponding quantum blocks. An exact correspondence between the classical irregular block and the SU(2) gauge theory twisted superpotential has been obtained as a result of another consistency check. The latter determines the spectrum of the 2-particle periodic Toda (sin-Gordon) Hamiltonian in accord with the Bethe/gauge correspondence. An analogue of this statement is found entirely within 2 d CFT. Namely, considering the classical limit of the null vector decoupling equation for the degenerate irregular block a celebrated Mathieu's equation is obtained with an eigenvalue determined by the classical irregular block. As it has been checked this result reproduces a well known weak coupling expansion of Mathieu's eigenvalue. Finally, yet another new formulae for Mathieu's eigenvalue relating the latter to a solution of certain Bethe-like equation are found.

  19. Classical limit of irregular blocks and Mathieu functions

    Energy Technology Data Exchange (ETDEWEB)

    Piątek, Marcin [Institute of Physics, University of Szczecin,ul. Wielkopolska 15, 70-451 Szczecin (Poland); Bogoliubov Laboratory of Theoretical Physics,Joint Institute for Nuclear Research, 141980 Dubna (Russian Federation); Pietrykowski, Artur R. [Institute of Theoretical Physics, University of Wroclaw,pl. M. Borna 9, 50-204 Wroclaw (Poland); Bogoliubov Laboratory of Theoretical Physics,Joint Institute for Nuclear Research, 141980 Dubna (Russian Federation)


    The Nekrasov-Shatashvili limit of the N = 2 SU(2) pure gauge (Ω-deformed) super Yang-Mills theory encodes the information about the spectrum of the Mathieu operator. On the other hand, the Mathieu equation emerges entirely within the frame of two-dimensional conformal field theory (2d CFT) as the classical limit of the null vector decoupling equation for some degenerate irregular block. Therefore, it seems to be possible to investigate the spectrum of the Mathieu operator employing the techniques of 2d CFT. To exploit this strategy, a full correspondence between the Mathieu equation and its realization within 2d CFT has to be established. In our previous paper, we have found that the expression of the Mathieu eigenvalue given in terms of the classical irregular block exactly coincides with the well known weak coupling expansion of this eigenvalue in the case in which the auxiliary parameter is the noninteger Floquet exponent. In the present work we verify that the formula for the corresponding eigenfunction obtained from the irregular block reproduces the so-called Mathieu exponent from which the noninteger order elliptic cosine and sine functions may be constructed. The derivation of the Mathieu equation within the formalism of 2d CFT is based on conjectures concerning the asymptotic behaviour of irregular blocks in the classical limit. A proof of these hypotheses is sketched. Finally, we speculate on how it could be possible to use the methods of 2d CFT in order to get from the irregular block the eigenvalues of the Mathieu operator in other regions of the coupling constant.

  20. Conduction system disease in fetuses evaluated for irregular cardiac rhythm. (United States)

    Cuneo, Bettina F; Strasburger, Janette F; Wakai, Ronald T; Ovadia, Marc


    To determine the prevalence of 1st and 2nd degree AV block in fetuses with an irregular cardiac rhythm, and to summarize outcome of these pregnancies. The diagnosis of irregular cardiac rhythm or 'skipped beats' includes isolated ectopy that resolves spontaneously. Recently, Doppler measurements of the 'mechanical' PR interval have been shown to identify AV conduction disease prenatally. Prenatal therapy of these conduction abnormalities may limit the progression to more advanced disease either in utero or after birth. A retrospective review was performed of fetuses evaluated between 1996 and 2004 with the findings of irregular cardiac rhythm. 1st or 2nd degree AV block was diagnosed on Doppler and M-mode recordings, and confirmed using either fetal magnetocardiography (fMCG) or postnatal 12-lead ECG. Dexamethasone was administered to 4 mothers with abnormal fetal AV conduction in the setting of anti-Ro/anti-La antibodies. Of 702 fetuses initially referred for arrhythmia, 306 had an irregular rhythm. Eight (2.6%) had intermittent 1st or 2nd degree AV block confirmed by fMCG and/or postnatal 12-lead ECG. AV block was presumed idiopathic in 2, associated with congenital long QT syndrome in 2 or with clinically unsuspected maternal anti-Ro or anti-La antibodies in 4. During the intrauterine period there was no progression to complete AV block and all were born alive at 34-40 weeks of gestation. A small but clinically significant population of fetuses with irregular rhythm will have 1st or 2nd degree AV block. Transplacental therapy may limit the intrauterine progression to more advanced disease. Copyright 2006 S. Karger AG, Basel.

  1. Classical limit of irregular blocks and Mathieu functions

    International Nuclear Information System (INIS)

    Piątek, Marcin; Pietrykowski, Artur R.


    The Nekrasov-Shatashvili limit of the N = 2 SU(2) pure gauge (Ω-deformed) super Yang-Mills theory encodes the information about the spectrum of the Mathieu operator. On the other hand, the Mathieu equation emerges entirely within the frame of two-dimensional conformal field theory (2d CFT) as the classical limit of the null vector decoupling equation for some degenerate irregular block. Therefore, it seems to be possible to investigate the spectrum of the Mathieu operator employing the techniques of 2d CFT. To exploit this strategy, a full correspondence between the Mathieu equation and its realization within 2d CFT has to be established. In our previous paper, we have found that the expression of the Mathieu eigenvalue given in terms of the classical irregular block exactly coincides with the well known weak coupling expansion of this eigenvalue in the case in which the auxiliary parameter is the noninteger Floquet exponent. In the present work we verify that the formula for the corresponding eigenfunction obtained from the irregular block reproduces the so-called Mathieu exponent from which the noninteger order elliptic cosine and sine functions may be constructed. The derivation of the Mathieu equation within the formalism of 2d CFT is based on conjectures concerning the asymptotic behaviour of irregular blocks in the classical limit. A proof of these hypotheses is sketched. Finally, we speculate on how it could be possible to use the methods of 2d CFT in order to get from the irregular block the eigenvalues of the Mathieu operator in other regions of the coupling constant.

  2. Factors associated with menstrual cycle irregularity and menopause. (United States)

    Bae, Jinju; Park, Susan; Kwon, Jin-Won


    A regular menstrual cycle is an important indicator of a healthy reproductive system. Previous studies reported obesity, stress, and smoking as the factors that are associated with irregular menstruation and early menopause. However, the integrative effects of these modifiable risk factors have not been fully understood. This study aimed to investigate the modifiable risk factors of menstrual cycle irregularity and premature menopause, as well as their individual and combined effects among adult women in Korea. This study selected adult women aged 19 years and above who had been included in the 2007-2014 Korean National Health and Nutrition Examination Survey. We used a separate dataset to analyze the risk factors of menstrual cycle irregularity and menopause (pre- and postmenopausal women: n = 4788 and n = 10,697, respectively). Univariate and multiple logistic regression analyses were conducted to evaluate the effects of smoking, drinking, obesity, and perceived level of stress on the menstrual cycle and menopause. Both logit and linear models were used in the analyses of the association between smoking and menopausal age. Equivalized household income, marital status, and educational level were considered as covariates. The modifiable risk factor scores were also calculated to integrate the effect of smoking, drinking, and obesity in the analysis. Results showed that smoking status, pack-year, obesity, and perceived level of stress were significantly associated with irregular menstruation among premenopausal women. Especially, women demonstrating > 3 modifiable risk factor scores had 1.7 times higher risk of having irregular menstruation than those who had a 0 score. Meanwhile, early initiation of smoking (≤19 years) and high pack-year (≥5) were also significantly associated with premature menopause among postmenopausal women. This study demonstrated that modifiable risk factors, such as smoking, obesity, and stress, were significantly associated

  3. The coevolutionary period of Wolbachia pipientis infecting Drosophila ananassae and its impact on the evolution of the host germline stem cell regulating genes. (United States)

    Choi, Jae Young; Aquadro, Charles F


    The endosymbiotic bacteria Wolbachia pipientis is known to infect a wide range of arthropod species yet less is known about the coevolutionary history it has with its hosts. Evidence of highly identical W. pipientis strains in evolutionary divergent hosts suggests horizontal transfer between hosts. For example, Drosophila ananassae is infected with a W. pipientis strain that is nearly identical in sequence to a strain that infects both D. simulans and D. suzukii, suggesting recent horizontal transfer among these three species. However, it is unknown whether the W. pipientis strain had recently invaded all three species or a more complex infectious dynamic underlies the horizontal transfers. Here, we have examined the coevolutionary history of D. ananassae and its resident W. pipientis to infer its period of infection. Phylogenetic analysis of D. ananassae mitochondrial DNA and W. pipientis DNA sequence diversity revealed the current W. pipientis infection is not recent. In addition, we examined the population genetics and molecular evolution of several germline stem cell (GSC) regulating genes of D. ananassae. These studies reveal significant evidence of recent and long-term positive selection at stonewall in D. ananassae, whereas pumillio showed patterns of variation consistent with only recent positive selection. Previous studies had found evidence for adaptive evolution of two key germline differentiation genes, bag of marbles (bam) and benign gonial cell neoplasm (bgcn), in D. melanogaster and D. simulans and proposed that the adaptive evolution at these two genes was driven by arms race between the host GSC and W. pipientis. However, we did not find any statistical departures from a neutral model of evolution for bam and bgcn in D. ananassae despite our new evidence that this species has been infected with W. pipientis for a period longer than the most recent infection in D. melanogaster. In the end, analyzing the GSC regulating genes individually showed two

  4. Teaching Teaching & Understanding Understanding

    DEFF Research Database (Denmark)


    "Teaching Teaching & Understanding Understanding" is a 19-minute award-winning short-film about teaching at university and higher-level educational institutions. It is based on the "Constructive Alignment" theory developed by Prof. John Biggs. The film delivers a foundation for understanding what...

  5. Formal and Substantial Irregularity of Procedural Acts in French Law

    Directory of Open Access Journals (Sweden)

    Hassan Mohseni


    Full Text Available Procedural acts may be invalid because of Formal or Substantial Irregularity. In French Procedural Law we can see a distinction between Invalidity of Instruments owning to Formal Irregularity and Invalidity of Documents by Reason of Essential Defect; a distinction that effects on nature and its plea time and subsequent regularization of document. Formal invalidity must be expressly provided for in Law, except where it is a case of a failure to comply with an important formality or one of public policy but Plea of invalidity based on failure to comply with substantive rules relating to written pleadings shall be admissible without the party raising them having to prove any prejudice to him even where the invalidity does not arise under express provisions.

  6. Irregular Migration - between legal status and social practices

    DEFF Research Database (Denmark)

    Lund Thomsen, Trine


    Publication History: Published Online: 2012-12-28 Abstract How do Polish migrant workers experience the process of migration and how does irregular migration status influence their life plans? In this article I analyse how the shifts between different legal statuses may be related to the social practices......Arnfinn H. and Rogstad, Jon 2.Book reviews by null 3.INVISIBLE IMMIGRANTS, VISIBLE EXPATS? Americans in Finnish discourses on immigration and internationalization by Leinonen, Johanna 4.Migrants in the Scandinavian Welfare State by Brochmann, Grete and Hagelund, Anniken 5.TOWARD AN IDENTITY STRESS....... Language and religious affiliations of an immigrant adolescent in Norway by Haque, Shahzaman View Top 20 Most Downloaded Articles Previous Article Next Article Go to table of contents Download full text pdf (PDF, 425 KB) Irregular Migration – Between Legal Status and Social Practices Narratives of Polish...

  7. The use of global ionospheric irregularity models for satellite communications (United States)

    Pope, J. H.


    Scintillation data obtained in the VHF region were used by Fremouw to develop a global scintillation model. An attempt has been made in the present study to improve this model in several respects. One of these is to modify the high latitude term in the model to better represent data obtained in the northern high latitude regions. Another improvement is the extention of the frequency region of validity to the L band and microwave regions. This attempt is based on certain theoretical considerations regarding the effects of distribution in irregularity sizes. Recent satellite in situ measurements indicate that the ionospheric irregularity description is functionally different from that assumed in the past. These satellite measurements are used in connection with the theoretical development to improve the model.

  8. Wettability measurements of irregular shapes with Wilhelmy plate method (United States)

    Park, Jaehyung; Pasaogullari, Ugur; Bonville, Leonard


    One of the most accurate methods for measuring the dynamic contact angle of liquids on solid surfaces is the Wilhelmy plate method. This method generally requires the use of rectangular samples having a constant perimeter in the liquid during advancing and receding cycles. A new formulation based on the Wilhelmy force balance equation to determine the contact angle for plate samples with irregular shapes has been developed. This method employs a profile plot obtained from an optical image to determine the perimeter (i.e. wetted length) of the sample as a function of the immersion depth. The raw force data measured by the force tensiometer is manipulated using the profile plot and the Wilhelmy equation to determine the wetting force and consequently advancing and the receding contact angle. This method is verified with both triangular and irregular PTFE samples in water, and measured contact angles are in good agreement with results from conventional regular shaped samples with a constant perimeter.

  9. Finding Causes of Irregular Headways Integrating Data Mining and AHP

    Directory of Open Access Journals (Sweden)

    Shi An


    Full Text Available Irregular headways could reduce the public transit service level heavily. Finding out the exact causes of irregular headways will greatly help to develop efficient strategies aiming to improve transit service quality. This paper utilizes bus GPS data of Harbin to evaluate the headway performance and proposes a statistical method to identify the abnormal headways. Association mining is used to dig deeper and recognize six causes of bus bunching. The AHP, embedded data analysis, is applied to determine the weight of each cause in the case of that these causes are combined with each other constantly. Results show that the front bus has a greater effect on bus bunching than the following bus, and the traffic condition is the most critical factor affecting bus headway.

  10. The scholarly rebellion of the early Baker Street Irregulars

    Directory of Open Access Journals (Sweden)

    George Mills


    Full Text Available This work provides and analyzes an early institutional history of the pioneering Sherlock Holmes American fan club, the Baker Street Irregulars (BSI. Using the publications and records of these devoted Sherlockians, I track the BSI's development from a speakeasy gathering in 1934 to a national organization by the mid-1940s. This growth was built on a foundation of Victorian nostalgia and playful humor. Yet at the same time the members of the Irregulars took their fandom seriously, producing Sherlockian scholarship and creating an infrastructure of journals, conferences, and credentialing that directly mimicked the academy. They positioned themselves in contrast to prevailing scholarly practices of the period, such as New Criticism. I trace both how their fan practices developed over time and how this conflict with the academy led to many of the BSI's defining characteristics.

  11. School setting and irregular lunch consumption among adolescents

    DEFF Research Database (Denmark)

    Pagh Pedersen, Trine; Holstein, Bjørn Evald; Rasmussen, Mette

    level variables and irregular lunch consumption. Lunch consumption was measured by lunch frequency questions. Results: We found that the school level factors, “Availability to canteen” and “Adult present in lunch breaks” were associated with irregular lunch consumption. Students with no access...... lunch consumption while the presence of an adult in lunch breaks promoted regular lunch consumption. Grade did to some extent modify the association. Most of the total variance in students’ lunch consumption was explained by individual level (98.2%)....... in a multilevel model controlled for factors at the individual level. Further, we investigated whether grade modified the association. Methods: We used data from the Danish 2010 contribution to the international collaborative cross-sectional study ‘Health Behaviour in School-Aged Children (HBSC). Data collection...

  12. Screening, Hyperuniformity, and Instability in the Sedimentation of Irregular Objects (United States)

    Goldfriend, Tomer; Diamant, Haim; Witten, Thomas A.


    We study the overdamped sedimentation of non-Brownian objects of irregular shape using fluctuating hydrodynamics. The anisotropic response of the objects to flow, caused by their tendency to align with gravity, directly suppresses concentration and velocity fluctuations. This allows the suspension to avoid the anomalous fluctuations predicted for suspensions of symmetric spheroids. The suppression of concentration fluctuations leads to a correlated, hyperuniform structure. For certain object shapes, the anisotropic response may act in the opposite direction, destabilizing uniform sedimentation.

  13. Designing an Irregular Tensegrity as a Monumental Object


    Buntara Sthenly Gan


    A novel and versatile numerical technique to solve a self-stress equilibrium state is adopted herein as a form-finding procedure for an irregular tensegrity structure. The numerical form-finding scheme of a tensegrity structure uses only the connectivity matrix and prototype tension coefficient vector as the initial guess solution. Any information on the symmetrical geometry or other predefined initial structural conditions is not necessary to get the solution in the form-finding process. An ...

  14. Drug Intoxicated Irregular Fighters: Complications, Dangers, and Responses (United States)


    witches, and other initiates over the use of psychoactive substances has, in many instances, disappeared, these substances are still in widespread use...purposes. Such consumption has led to unpredictable fighting, the commission of atrocities, and to the prolongation of internal violence. The presence...fighters. Drug consumption in contemporary wars has coincided with the use of child soldiers, has led to increased unpredictability among irregular

  15. Professional Irregular Defense Forces: The Other Side of COIN (United States)


    capability, which, in different shapes or forms, threatens an adversary with out-of-proportion losses in case of attack.50 Every deterrence strategy...from 1808 to 1814. John Arquilla, Insurgents, Raiders and Bandits: How Masters of Irregular Warfare Have Shaped Our World, (Maryland: The Rowman and...Farmers produced motor fuel from coconut, made sausages , and smoked meat, and jam and fruit juice were also produced. “Boots were made from the skins of

  16. Computing Homology Group Generators of Images Using Irregular Graph Pyramids


    Peltier , Samuel; Ion , Adrian; Haxhimusa , Yll; Kropatsch , Walter; Damiand , Guillaume


    International audience; We introduce a method for computing homology groups and their generators of a 2D image, using a hierarchical structure i.e. irregular graph pyramid. Starting from an image, a hierarchy of the image is built, by two operations that preserve homology of each region. Instead of computing homology generators in the base where the number of entities (cells) is large, we first reduce the number of cells by a graph pyramid. Then homology generators are computed efficiently on...

  17. Sorting on Reconfigurable Meshes: An Irregular Decomposition Approach


    Lai, Ten H.; Sheng, Ming-Jye


    Most algorithms for reconfigurable meshes (R-meshes) are based on the divide-and-conquer (DAC) strategy. Although the strategy per se does not require the subproblems to be equal in size, existing DAC algorithms for R-meshes do divide the problem approximately evenly. This paper demonstrates that dividing a problem evenly is not necessarily a good way to decompose a problem. There are occasions on which an irregular decomposition scheme may be preferable. We take this approach ...

  18. Track Irregularity Time Series Analysis and Trend Forecasting


    Jia Chaolong; Xu Weixiang; Wang Futian; Wang Hanning


    The combination of linear and nonlinear methods is widely used in the prediction of time series data. This paper analyzes track irregularity time series data by using gray incidence degree models and methods of data transformation, trying to find the connotative relationship between the time series data. In this paper, GM (1,1) is based on first-order, single variable linear differential equations; after an adaptive improvement and error correction, it is used to predict the long-term changin...

  19. Using Little's Irregularity Index in orthodontics: outdated and inaccurate?

    LENUS (Irish Health Repository)

    Macauley, Donal


    Little\\'s Irregularity Index (LII) was devised to objectively score mandibular incisor alignment for epidemiological studies but has been extended to assess the relative performance of orthodontic brackets, retainer or treatment modalities. Our aim was to examine the repeatability and precision of LII measurements of four independent examiners on the maxillary arch of orthodontic patients. The hypothesis was that the reproducibility of individual contact point displacement measurements, used to calculate the LII score, are inappropriate.

  20. [Comparision of Different Methods of Area Measurement in Irregular Scar]. (United States)

    Ran, D; Li, W J; Sun, Q G; Li, J Q; Xia, Q


    To determine a measurement standard of irregular scar area by comparing the advantages and disadvantages of different measurement methods in measuring same irregular scar area. Irregular scar area was scanned by digital scanning and measured by coordinate reading method, AutoCAD pixel method, Photoshop lasso pixel method, Photoshop magic bar filled pixel method and Foxit PDF reading software, and some aspects of these methods such as measurement time, repeatability, whether could be recorded and whether could be traced were compared and analyzed. There was no significant difference in the scar areas by the measurement methods above. However, there was statistical difference in the measurement time and repeatability by one or multi performers and only Foxit PDF reading software could be traced back. The methods above can be used for measuring scar area, but each one has its advantages and disadvantages. It is necessary to develop new measurement software for forensic identification. Copyright© by the Editorial Department of Journal of Forensic Medicine

  1. Decreased resting metabolic rate in ballet dancers with menstrual irregularity. (United States)

    Myburgh, K H; Berman, C; Novick, I; Noakes, T; Lambert, E


    We studied 21 ballet dancers aged 19.4 +/- 1.4 years, hypothesizing that undernutrition was a major factor in menstrual irregularity in this population. Menstrual history was determined by questionnaire. Eight dancers had always been regular (R). Thirteen subjects had a history of menstrual irregularity (HI). Of these, 2 were currently regularly menstruating, 3 had short cycles, 6 were oligomenorrheic, and 2 were amenorrheic. Subjects completed a weighed dietary record and an Eating Attitudes Test (EAT). The following physiological parameters were measured: body composition by anthropometry, resting metabolic rate (RMR) by open-circuit indirect calorimetry, and serum thyroid hormone concentrations by radioimmunoassay. R subjects had significantly higher RMR than HI subjects. Also, HI subjects had lower RMR than predicted by fat-free mass, compared to the R subjects. Neither reported energy intake nor serum thyroid hormone concentrations were different between R and HI subjects. EAT scores varied and were not different between groups. We concluded that in ballet dancers, low RMR is more strongly associated with menstrual irregularity than is current reported energy intake or serum thyroid hormone concentrations.

  2. Gas and Dust Properties in Dwarf Irregular Galaxies (United States)

    Jones, A. P.; Madden, S. C.; Colgan, S. W. J.; Geis, N.; Haas, M.; Maloney, P.; Nikola, T.; Poglitsch, A.


    We present a study of the 158 (micron)meter [C II] fine structure emission line from a sample of 11 low metallicity irregular galaxies using the NASA Kuiper Airborne Observatory (KAO). Our preliminary results demonstrate that the ratio of the 158 (micron)meter [C II] emission to the CO-12(1 yields 0) emission ranges from 6,000 to 46,000. These ratios are significantly enhanced relative to clouds within the Galaxy and to normal metallicity galaxies, which typically have values in the range 2,000 to 6,300. We also find that the [C II] emission in dwarf irregular galaxies can be up to 5% of the far-infrared (FIR) emission, a higher fraction of the FIR than in normal metallicity galaxies. We discuss these results for the dwarf irregular galaxies and compare them to those observed in normal metallicity galaxies. The enhanced 158 (micron)meter [C II] emission relative to CO-12(1 yields 0) emission can be understood in terms of the increased penetration depth of ultraviolet (UV) photons into the clouds in low metallicity environments.

  3. Flow induced vibrations in arrays of irregularly spaced cylinders (United States)

    Taub, Gordon; Michelin, Sébastien


    Historically the main industrial applications of cylinder arrays in cross flows favored regular arrangements of cylinders. For this reason, most past studies of Flow Induced Vibrations (FIV) in large cylinder arrays have focused on such arrangements. Recently there has been some interest in generating renewable energy using FIV of bluff bodies. In such applications it will likely be beneficial to enhance, rather than suppress FIV. It is not known a priori if regular or irregularly spaced arrays are most adequate for this type of application. In this study, wind tunnel experiments were conducted on one regularly spaced array and four different irregularly spaced arrays of cylinders in a cross flow. Each arrangement of cylinders was examined under eight different orientations to a cross flow ranging between 10 m/s and 17 m/s. The average amplitude of vibration of the cylinders was found to highly depend on arrangement and orientation. The typical amplitude of vibration of the rods in the irregular arrangements were found to be an order of magnitude larger than that of the regular array. A simple model was proposed in order to predict if a given arrangement was likely to produce large oscillations, and the validity of the model was examined. This research was supported by a Marie Curie International Reintegration Grant within the 7th European Community Framework Program (Grant PIRG08-GA-2010-276762).

  4. Modeling of aluminum-silicon irregular eutectic growth by cellular automaton model

    Directory of Open Access Journals (Sweden)

    Rui Chen


    Full Text Available Due to the extensive application of Al-Si alloys in the automotive and aerospace industries as structural components, an understanding of their microstructural formation, such as dendrite and (Al+Si eutectic, is of great importance to control the desirable microstructure, so as to modify the performance of castings. Since previous major themes of microstructural simulation are dendrite and regular eutectic growth, few efforts have been paid to simulate the irregular eutectic growth. Therefore, a multiphase cellular automaton (CA model is developed and applied to simulate the time-dependent Al-Si irregular eutectic growth. Prior to model establishment, related experiments were carried out to investigate the influence of cooling rate and Sr modification on the growth of eutectic Si. This CA model incorporates several aspects, including growth algorithms and nucleation criterion, to achieve the competitive and cooperative growth mechanism for nonfaceted-faceted Al-Si irregular eutectic. The growth kinetics considers thermal undercooling, constitutional undercooling, and curvature undercooling, as well as the anisotropic characteristic of eutectic Si growth. The capturing rule takes into account the effects of modification on the silicon growth behaviors. The simulated results indicate that for unmodified alloy, the higher eutectic undercooling results in the higher eutectic growth velocity, and a more refined eutectic microstructure as well as narrower eutectic lamellar spacing. For modified alloy, the eutectic silicon tends to be obvious fibrous morphology and the morphology of eutectic Si is determined by both chemical modifier and cooling rate. The predicted microstructure of Al-7Si alloy under different solidification conditions shows that this proposed model can successfully reproduce both dendrite and eutectic microstructures.

  5. Integrated Swarming Operations for Air Base Defense: Applications in Irregular Warfare

    National Research Council Canada - National Science Library

    Gray, Ron


    .... However, in low-intensity conflicts (LICs) or irregular warfare (IW) campaigns, U.S. forces are faced with an irregular enemy, one that does not choose to fight its forces directly, but rather through unconventional or indirect methods...

  6. Irregular analytical errors in diagnostic testing - a novel concept. (United States)

    Vogeser, Michael; Seger, Christoph


    In laboratory medicine, routine periodic analyses for internal and external quality control measurements interpreted by statistical methods are mandatory for batch clearance. Data analysis of these process-oriented measurements allows for insight into random analytical variation and systematic calibration bias over time. However, in such a setting, any individual sample is not under individual quality control. The quality control measurements act only at the batch level. Quantitative or qualitative data derived for many effects and interferences associated with an individual diagnostic sample can compromise any analyte. It is obvious that a process for a quality-control-sample-based approach of quality assurance is not sensitive to such errors. To address the potential causes and nature of such analytical interference in individual samples more systematically, we suggest the introduction of a new term called the irregular (individual) analytical error. Practically, this term can be applied in any analytical assay that is traceable to a reference measurement system. For an individual sample an irregular analytical error is defined as an inaccuracy (which is the deviation from a reference measurement procedure result) of a test result that is so high it cannot be explained by measurement uncertainty of the utilized routine assay operating within the accepted limitations of the associated process quality control measurements. The deviation can be defined as the linear combination of the process measurement uncertainty and the method bias for the reference measurement system. Such errors should be coined irregular analytical errors of the individual sample. The measurement result is compromised either by an irregular effect associated with the individual composition (matrix) of the sample or an individual single sample associated processing error in the analytical process. Currently, the availability of reference measurement procedures is still highly limited, but LC

  7. Study of Track Irregularity Time Series Calibration and Variation Pattern at Unit Section

    Directory of Open Access Journals (Sweden)

    Chaolong Jia


    Full Text Available Focusing on problems existing in track irregularity time series data quality, this paper first presents abnormal data identification, data offset correction algorithm, local outlier data identification, and noise cancellation algorithms. And then proposes track irregularity time series decomposition and reconstruction through the wavelet decomposition and reconstruction approach. Finally, the patterns and features of track irregularity standard deviation data sequence in unit sections are studied, and the changing trend of track irregularity time series is discovered and described.

  8. Irregular designs and Darwinism in biology: Genomes as the test case

    Indian Academy of Sciences (India)

    B J Rao

    -living worlds) in fact has created a mid-way solution to this 'quandary' of irregular designs by offering recursive periodicity and/or symmetry even within 'irregular shapes'. While symmetry in irregular designs was long appreciated by mankind, ...

  9. Optimización de la distribución de piezas irregulares en chapas // Irregular parts nesting problem optimization.

    Directory of Open Access Journals (Sweden)

    A. M. Lastres - Aleaga


    Full Text Available ResumenEn el presente artículo se realiza un estudio de diferentes esquemas de solución reflejados en laliteratura, que tratan el problema de la distribución de piezas irregulares en superficies planas conanidamiento bidimensional (Nesting. Fueron analizados diferentes esquemas de solución, siendolos que consideran la geometría real de la pieza, durante la evaluación y posicionamiento de lasmismas sobre la superficie a cortar, los que garantizan el mayor aprovechamiento del material. Elesquema propuesto se caracteriza por un tratamiento gráfico de las piezas que permite acelerar elproceso de reconocimiento y evaluación de opciones de acoplamiento entre ellas, así como lacreación de poblaciones de conglomerados crecientes para su ubicación definitiva en la superficie acortar. En la generación de poblaciones de opciones de solución, se utiliza un algoritmo derivado delmétodo de Integración de Variables, además se realiza la comparación de los resultados obtenidospor el método propuesto, con otros resultados generados por procedimientos desarrollados pordiferentes autores, alcanzando mejorar los valores de aprovechamiento de material y la reduccióndel tiempo de generación de soluciones.Palabras claves: Distribución de piezas irregulares en superficies; optimización; Métodos Evolutivos;_________________________________________________________________________AbstractIn this article, we study various solution schemes reported in the literature, which deal with theproblem of irregular parts distribution on flat surfaces with two-dimensional nesting. Different solutionschemes were analyzed, which they consider to be the real geometry of the part, during theevaluation and positioning them on the surface to be cut, ensuring the best use of the material. Theproposed scheme is characterized by a graphic treatment of the pieces that can accelerate theprocess of recognition and evaluation of options coupling between them, as well as

  10. Endodontic management of a maxillary lateral incisor with dens invaginatus and external root irregularity using cone-beam computed tomography

    Directory of Open Access Journals (Sweden)

    Young-Jun Lim


    Full Text Available Cone-beam computed tomography (CBCT is a useful diagnostic tool for identification of both internal and external root configurations. This case report describes the endodontic management of a lateral incisor with both dens invaginatus and external root irregularity by using CBCT. Nonsurgical endodontic retreatment was performed on the lateral incisor with dens invaginatus. A perforation through the dens invaginatus and external concavity was repaired using mineral trioxide aggregate. After 18 mon of follow-up, there were no clinical symptoms. Recall radiographs appeared normal and showed healing of the periapical pathosis. The understanding of both internal root canal configuration and external root irregularity using CBCT can ensure predictable and successful results.

  11. Slow Drift-Oscillations of a Ship in Irregular Waves

    Directory of Open Access Journals (Sweden)

    Odd M. Faltinsen


    Full Text Available A procedure to calculate horizontal slow drift excitation forces on an infinitely long horizontal cylinder in irregular beam sea waves is presented. The hydrodynamic boundary-value problem is solved correctly to second order in wave amplitude. Results in the form of second order transfer functions are presented for different, two-dimensional shapes. It is concluded that Newman's approximative method is a practical way to calculate slow drift excitation forces on a ship in beam sea and it is suggested that it may be used in a more general case. Applications of the results for moored ships are discussed.

  12. Ionospheric wave and irregularity measurements using passive radio astronomy techniques

    International Nuclear Information System (INIS)

    Erickson, W.C.; Mahoney, M.J.; Jacobson, A.R.; Knowles, S.H.


    The observation of midlatitude structures using passive radio astronomy techniques is discussed, with particular attention being given to the low-frequency radio telescope at the Clark Lake Radio Observatory. The present telescope operates in the 10-125-MHz frequency range. Observations of the ionosphere at separations of a few kilometers to a few hundreds of kilometers by the lines of sight to sources are possible, allowing the determination of the amplitude, wavelength, direction of propagation, and propagation speed of ionospheric waves. Data are considered on large-scale ionospheric gradients and the two-dimensional shapes and sizes of ionospheric irregularities. 10 references

  13. Modelling of Ionospheric Irregularities and Total Electron Content. (United States)


    Total electron content changes 559, 1980. associated with equatorial irregularity plumes, Yeh, K.C., H. Soicher, C.H. Liu, and E. Bonelli , Paper...and GONZALES V. H. 1960 J. geophys. Res. 65, 3209. .,*’_*, YEn K. C., SOICHER H., Liu C. H. 1979a Geophys. Res. Lett. 6, 473. and BONELLI E.1,*,E Y K...and J. Aarons (1980), Studies of equatorial ir- Yeh. K. C., H. Soicher. C. H. Liu, and E. Bonelli (1979b). lono- regularity patches using SIRIO VHF

  14. Third-order theory for multi-directional irregular waves

    DEFF Research Database (Denmark)

    Madsen, Per A.; Fuhrman, David R.


    A new third-order solution for multi-directional irregular water waves in finite water depth is presented. The solution includes explicit expressions for the surface elevation, the amplitude dispersion and the vertical variation of the velocity potential. Expressions for the velocity potential...... breaks down due to singularities in the transfer functions. We analyse harmonic resonance for the case of a monochromatic short-crested wave interacting with a plane wave having a different frequency, and make long-term simulations with a high-order Boussinesq formulation in order to study the evolution...... of wave trains exposed to harmonic resonance....

  15. Method for Achieving Irregular Boundary Area for Complete Fluidic Sprinkler (United States)

    Liu, Junping; Yuan, Shouqi; Li, Hong; Zhu, Xingye

    For resolving the problem of sprinkle repeated, overtaken and went beyond in irrigation, it is important to research the approach of irregular boundary area. The equation of range and flow for achieving the square and triangle spray were deduced. Pressure is proportional to range. Specific method of changing the sectional area was put forward for achieving square and triangle spray. Adopted MATLAB language editor to analyzing the theoretical relation and emulate for achieving square and triangle spray. The experiments of theory pressure were carried out. The results showed that the experimental value were consistent with the theoretical value.

  16. Human Rights of Irregular Immigrants: A Challenge for the Universality of Human Rights

    Directory of Open Access Journals (Sweden)

    Luljeta Ikonomi


    Full Text Available Irregular immigration is a phenomenon with a substantial impact for the majority of the countries. The paper analyses whether there is an adequate human rights framework for protection of irregular immigrants or whether the irregular status exempts the migrants from the protection of international human rights law. If this is the case, then the human rights universality has failed. The paper takes into consideration the developments in the International and EU Law, as well as in the jurisprudence of the international tribunals regarding protection of irregular immigrants. It is divided into three main sections. The first section informs briefly on the dynamics of irregular immigrants; the second section analyses the legislation on irregular immigration from the perspective of the state sovereignty, the third section analyses the human rights law and the protection it affords to irregular immigrants, pursuant to the interpretation of International tribunals.

  17. Major depression in China-to-US immigrants and US-born Chinese Americans: testing a hypothesis from culture-gene co-evolutionary theory of mental disorders. (United States)

    Tan, Tony Xing


    In this study, the culture-gene co-evolutionary theory of mental disorders was used to test the hypothesis that major depression was less prevalent in China-to-US immigrants who migrated to the US as adults than in US-born adult Chinese Americans. Data from the Collaborative Psychiatric Epidemiology Surveys (CPES) were extracted for secondary data analyses on the rates of major depression disorder (MDD) and major depressive episode (MDE) in the two groups. Findings showed that for life time MDD, the rates for China-to-US immigrant and US-born Chinese were 5.3% and 7.9% for men and 8.5% and 33.1% for women. For 12-month MDD, the corresponding rates were 2.2% and 3.4% for men, and 4.7% and 12.6% for women. For life time MDE, the corresponding rates were 6.8% and 8.8% for men; for women the rates were 8.5% and 33.1%. For 12-month MDE, the rates were 2.2% and 4.4% for men; the rates were 4.7% and 12.6% for women. Controlling for age, education level, income, BMI, marital status, and income-to-needs ratio, China-to-US immigrant women remained less likely to have life time major depression than US-born Chinese American women. While the study has the strength of utilizing nationally representative datasets, the approach is limited as the data sources lack the capacity to investigate how the strength of connection with the collectivist culture might be related to major depression in the immigrant group. Copyright © 2014 Elsevier B.V. All rights reserved.

  18. Size and Albedo of Irregular Saturnian Satellites from Spitzer Observations (United States)

    Mueller, Michael; Grav, T.; Trilling, D.; Stansberry, J.; Sykes, M.


    Using MIPS onboard the Spitzer Space Telescope, we observed the thermal emission (24 and, for some targets, 70 um) of eight irregular satellites of Saturn: Albiorix, Siarnaq, Paaliaq, Kiviuq, Ijiraq, Tarvos, Erriapus, and Ymir. We determined the size and albedo of all targets. An analysis of archived MIPS observations of Phoebe reproduces Cassini results very accurately, thereby validating our method. For all targets, the geometric albedo is found to be low, probably below 10% and clearly below 15%. Irregular satellites are much darker than the large regular satellites. Their albedo is, however, quite similar to that of small bodies in the outer Solar System (such as cometary nuclei, Jupiter Trojans, or TNOs). This is consistent with color measurements as well as dynamical considerations which suggest a common origin of the said populations. There appear to be significant object-to-object albedo differences. Similar albedos found for some members of dynamical clusters support the idea that they may have originated in the breakup of a parent body. For three satellites, thermal data at two wavelengths are available, enabling us to constrain their thermal properties. Sub-solar temperatures are similar to that found from Cassini's Phoebe fly-by. This suggests a rather low thermal inertia, as expected for regolith-covered objects. This work is based on observations made with the Spitzer Space Telescope, which is operated by JPL under a contract with NASA. Support for this work was provided by NASA.

  19. [Irregular blood group antibodies during pregnancy: screening is mandatory]. (United States)

    Semmekrot, B A; de Man, A J; Boekkooi, P F; van Dijk, B A


    During pregnancy irregular blood group antibodies, originating either from earlier pregnancies or from blood transfusions, may severely jeopardize both mother and child. Three patients are described with pregnancy-associated blood group incompatibility. In one case of Kell antagonism a previous child had reportedly died of cot death, but in retrospect it had most probably suffered from erythroblastosis fetalis as a result of anti Kell antibodies. In the second case, a twin pregnancy, the diagnosis of neonatal haemolytic anaemia on the basis of blood group incompatibility with a very rare antibody (anti-Kpb) had been established in the previous child. No precautions had been taken during this pregnancy, putting both mother and children at risk. All three children recovered, the twins after repeated transfusion of Kpb-free erythrocytes. The described cases emphasize the importance of being informed about the presence of antibodies during pregnancy. Such information can only be obtained by assessing the antibody status during pregnancy. In the Netherlands, the screening of all pregnant women for the presence of irregular antibodies was introduced last year.

  20. 3D Reconstruction of Irregular Buildings and Buddha Statues (United States)

    Zhang, K.; Li, M.-j.


    Three-dimensional laser scanning could acquire object's surface data quickly and accurately. However, the post-processing of point cloud is not perfect and could be improved. Based on the study of 3D laser scanning technology, this paper describes the details of solutions to modelling irregular ancient buildings and Buddha statues in Jinshan Temple, which aiming at data acquisition, modelling and texture mapping, etc. In order to modelling irregular ancient buildings effectively, the structure of each building is extracted manually by point cloud and the textures are mapped by the software of 3ds Max. The methods clearly combine 3D laser scanning technology with traditional modelling methods, and greatly improves the efficiency and accuracy of the ancient buildings restored. On the other hand, the main idea of modelling statues is regarded as modelling objects in reverse engineering. The digital model of statues obtained is not just vivid, but also accurate in the field of surveying and mapping. On this basis, a 3D scene of Jinshan Temple is reconstructed, which proves the validity of the solutions.

  1. Model tracking dual stochastic controller design under irregular internal noises

    International Nuclear Information System (INIS)

    Lee, Jong Bok; Heo, Hoon; Cho, Yun Hyun; Ji, Tae Young


    Although many methods about the control of irregular external noise have been introduced and implemented, it is still necessary to design a controller that will be more effective and efficient methods to exclude for various noises. Accumulation of errors due to model tracking, internal noises (thermal noise, shot noise and l/f noise) that come from elements such as resistor, diode and transistor etc. in the circuit system and numerical errors due to digital process often destabilize the system and reduce the system performance. New stochastic controller is adopted to remove those noises using conventional controller simultaneously. Design method of a model tracking dual controller is proposed to improve the stability of system while removing external and internal noises. In the study, design process of the model tracking dual stochastic controller is introduced that improves system performance and guarantees robustness under irregular internal noises which can be created internally. The model tracking dual stochastic controller utilizing F-P-K stochastic control technique developed earlier is implemented to reveal its performance via simulation

  2. Inventory Management for Irregular Shipment of Goods in Distribution Centre (United States)

    Takeda, Hitoshi; Kitaoka, Masatoshi; Usuki, Jun


    The shipping amount of commodity goods (Foods, confectionery, dairy products, such as public cosmetic pharmaceutical products) changes irregularly at the distribution center dealing with the general consumer goods. Because the shipment time and the amount of the shipment are irregular, the demand forecast becomes very difficult. For this, the inventory control becomes difficult, too. It cannot be applied to the shipment of the commodity by the conventional inventory control methods. This paper proposes the method for inventory control by cumulative flow curve method. It proposed the method of deciding the order quantity of the inventory control by the cumulative flow curve. Here, it proposes three methods. 1) Power method,2) Polynomial method and 3)Revised Holt's linear method that forecasts data with trends that is a kind of exponential smoothing method. This paper compares the economics of the conventional method, which is managed by the experienced and three new proposed methods. And, the effectiveness of the proposal method is verified from the numerical calculations.

  3. Using Radio Irregularity for Increasing Residential Energy Awareness

    Directory of Open Access Journals (Sweden)

    A. Miljković


    Full Text Available Radio irregularity phenomenon is often considered as a shortcoming of wireless networks. In this paper, the method of using radio irregularity as an efficient human presence detection sensor in smart homes is presented. The method is mainly based on monitoring variations of the received signal strength indicator (RSSI within the messages used for the communication between wireless smart power outlets. The radio signals used for the inter-outlets communication can be absorbed, diffracted or reflected by objects in their propagation paths. When a human enters the existing radio communication field, the variation of the signal strength at the receiver is even more expressed. Based on the detected changes and compared to the initial thresholds set during the initialization phase, the system detects human presence. The proposed solution increases user awareness and automates the power control in households, with the primary goal to contribute in residential energy savings. Compared to conventional sensor networks, this approach preserves the sensorial intelligence, simplicity and low installation costs, without the need for additional sensors integration.

  4. «European Cossacks» in XVI–XVII Centuries: the Phenomenon of Irregularity from the Adriatic Sea to the Urals

    Directory of Open Access Journals (Sweden)

    Artyom Y. Peretyatko


    Full Text Available The article is devoted to the history of Eastern European irregular troops, widely spread in Russia, in the Polish–Lithuanian Commonwealth and in the Habsburg possessions in the XVI–XVII century. It substantiates the position that all such troops, in particular, the Cossacks, Grenz infantry and lancers, was a single phenomenon, and to understand some of the peculiarities of their evolution should consider their history comprehensively. Based on the approaches proposed by F. Mehring, the article concludes that the proliferation of irregular parts in the Christian Eastern Europe was the result of specific socio-political conditions, especially long wars and borders of the Asian type. In these circumstances, governments were created or were invited to the service of paramilitary units, instead of receiving wages various benefits. The result is a system of irregular troops, the geographical scope of which was limited to the Adriatic sea and the Urals.

  5. Towards generalizing co-evolutionary dynamics of socio-hydrology: Theoretical frameworks of cultural evolution and robustness-fragility tradeoff (United States)

    Oh, W. S.; Yu, D. J.; Davis, T.; Hillis, V.; Waring, T. M.


    One ongoing challenge to socio-hydrology is the problem of generalization: to what extent do common human-water co-evolutions exist across distinct cases and what are underlying mechanisms of these co-evolutions. This problem stems in part from a lack of unifying theories in socio-hydrology, which hinders the explanation and generalization of results between cases in different regions. Theories help an analyst to make assumptions that are necessary to diagnose a specific phenomenon, to explain the general mechanisms of causation, and, thus, to predict future outcomes. To help address the issue, this study introduces two theories that are increasingly used in the fields of sustainability science and social-ecological systems research: robustness-fragility tradeoff (RFTO) and cultural multi-level selection (CMLS). We apply each of these theories to two distinct cases (water management issues in southwest Bangladesh and the Kissimmee River Basin, Florida) and interpret the phenomena of the levee and adaptation effects. CMLS and RFTO focus on complementary aspects of socio-hydrological phenomena. The theory of RFTO, which is mostly about inherent tradeoffs associated with infrastructure improvements, explains how efforts to increase system robustness can generate hidden endogenous risks. CMLS theory, rooted in the broader theory of cultural evolution, concerns how human cultural dynamics can act as an endogenous driver of system change across multiple levels of social organizations. Using the applied examples, we demonstrate that these two theories can provide an effective way to study social-hydrological systems and to overcome the generalization problem. Our work shows that multiple theories can be synthesized to give a richer understanding of diverse socio-hydrological patterns.

  6. Coevolutionary Dynamics of Rice Blast Resistance Gene Pi-ta and Magnaporthe oryzae Avirulence Gene AVR-Pita 1. (United States)

    Jia, Yulin; Zhou, Erxun; Lee, Seonghee; Bianco, Tracy


    The Pi-ta gene in rice is effective in preventing infections by Magnaporthe oryzae strains that contain the corresponding avirulence gene, AVR-Pita1. Diverse haplotypes of AVR-Pita1 have been identified from isolates of M. oryzae from rice production areas in the United States and worldwide. DNA sequencing and mapping studies have revealed that AVR-Pita1 is highly unstable, while expression analysis and quantitative resistance loci mapping of the Pi-ta locus revealed complex evolutionary mechanisms of Pi-ta-mediated resistance. Among these studies, several Pi-ta transcripts were identified, most of which are probably derived from alternative splicing and exon skipping, which could produce functional resistance proteins that support a new concept of coevolution of Pi-ta and AVR-Pita1. User-friendly DNA markers for Pi-ta have been developed to support marker-assisted selection, and development of new rice varieties with the Pi-ta markers. Genome-wide association studies revealed a link between Pi-ta-mediated resistance and yield components suggesting that rice has evolved a complicated defense mechanism against the blast fungus. In this review, we detail the current understanding of Pi-ta allelic variation, its linkage with rice productivity, AVR-Pita allelic variation, and the coevolution of Pi-ta and AVR-Pita in Oryza species and M. oryzae populations, respectively. We also review the genetic and molecular basis of Pi-ta and AVR-Pita interaction, and its value in marker-assisted selection and engineering resistance.

  7. A Model Based Deconvolution Approach for Creating Surface Composition Maps of Irregularly Shaped Bodies from Limited Orbiting Nuclear Spectrometer Measurements (United States)

    Dallmann, N. A.; Carlsten, B. E.; Stonehill, L. C.


    Orbiting nuclear spectrometers have contributed significantly to our understanding of the composition of solar system bodies. Gamma rays and neutrons are produced within the surfaces of bodies by impacting galactic cosmic rays (GCR) and by intrinsic radionuclide decay. Measuring the flux and energy spectrum of these products at one point in an orbit elucidates the elemental content of the area in view. Deconvolution of measurements from many spatially registered orbit points can produce detailed maps of elemental abundances. In applying these well-established techniques to small and irregularly shaped bodies like Phobos, one encounters unique challenges beyond those of a large spheroid. Polar mapping orbits are not possible for Phobos and quasistatic orbits will realize only modest inclinations unavoidably limiting surface coverage and creating North-South ambiguities in deconvolution. The irregular shape causes self-shadowing both of the body to the spectrometer but also of the body to the incoming GCR. The view angle to the surface normal as well as the distance between the surface and the spectrometer is highly irregular. These characteristics can be synthesized into a complicated and continuously changing measurement system point spread function. We have begun to explore different model-based, statistically rigorous, iterative deconvolution methods to produce elemental abundance maps for a proposed future investigation of Phobos. By incorporating the satellite orbit, the existing high accuracy shape-models of Phobos, and the spectrometer response function, a detailed and accurate system model can be constructed. Many aspects of this model formation are particularly well suited to modern graphics processing techniques and parallel processing. We will present the current status and preliminary visualizations of the Phobos measurement system model. We will also discuss different deconvolution strategies and their relative merit in statistical rigor, stability

  8. Pesquisa de anticorpos irregulares: estudo retrospectivo entre 2007 e 2012


    Barradas, A; Barra, A; Cardoso, E; Costa, C; Ferreira, R; Pereira, F


    Introdução: A aloimunização depende não só da exposição do receptor a um antigénio estranho, mas também da imunogenicidade deste. A exposição a substâncias reconhecidas como não-próprias do organismo, como os antigénios eritrocitários, pode desencadear ativação do sistema imune com formação de anticorpos, destruindo os eritrócitos transfundidos e determinando assim o seu significado clínico. São designados por anticorpos irregulares ou aloanticorpos. Ocorrem em aproximadamente 0,3 a 2% da pop...

  9. Irregular fog as a water source for desert dune beetles. (United States)

    Seely, M K


    Three methods of fog-water uptake have been observed in three tribes of Namib desert dune tenebrionid beetles, Adesmiini, Eurychorini and Zophosini. The methods used correlate with distribution and gross morphology of each species but cut across phylogenetic affinities. Of the three methods described, none involve obvious fine anatomical or physical adaptations of the beetles for fog-water uptake. Rather, the beetles have evolved specific behavioural patterns for drinking water condensed on vegetation, their own dorsum or sand.Use of fog-water necessitates surface activity at times when surface temperatures and wind velocities are not optimal for these diurnal or crepuscular species. Behavioural adaptation has enabled these beetles to use irregular and unpredictable fogs as a moisture source.

  10. The Orbits of Jupiter’s Irregular Satellites (United States)

    Brozović, Marina; Jacobson, Robert A.


    We report on the improved ephemerides for the irregular Jovian satellites. We used a combination of numerically integrated equations of motion and a weighted least-squares algorithm to fit the astrometric measurements. The orbital fits for 59 satellites are summarized in terms of state vectors, post-fit residuals, and mean orbital elements. The current data set appears to be sensitive to the mass of Himalia, which is constrained to the range of GM = 0.13-0.28 km3 s-2. Here, GM is the product of the Newtonian constant of gravitation, G and the body's mass, M. Our analysis of the orbital uncertainties indicates that 11 out of 59 satellites are lost owing to short data arcs. The lost satellites hold provisional International Astronomical Union (IAU) designations and will likely need to be rediscovered.

  11. Computer-Generated Experimental Designs for Irregular-Shaped Regions

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, Nam K.; Piepel, Gregory F.


    This paper focuses on the construction of computer-generated designs on irregularly-shaped, constrained regions. Overviews of the Fedorov exchange algorithm (FEA) and other exchange algorithms for the construction of D-optimal designs are given. A faster implementation of the FEA is presented, which is referred to as fast-FEA (denoted FFEA). The FFEA was applied to construct D-optimal designs for several published examples with constrained experimental regions. Designs resulting from the FFEA are more D-efficient than published designs, and provide benchmarks for future comparisons of design construction algorithms. The construction of G-optimal designs for constrained regions is also discussed and illustrated with a published example.

  12. Massive stars in the Sagittarius Dwarf Irregular Galaxy (United States)

    Garcia, Miriam


    Low metallicity massive stars hold the key to interpret numerous processes in the past Universe including re-ionization, starburst galaxies, high-redshift supernovae, and γ-ray bursts. The Sagittarius Dwarf Irregular Galaxy [SagDIG, 12+log(O/H) = 7.37] represents an important landmark in the quest for analogues accessible with 10-m class telescopes. This Letter presents low-resolution spectroscopy executed with the Gran Telescopio Canarias that confirms that SagDIG hosts massive stars. The observations unveiled three OBA-type stars and one red supergiant candidate. Pending confirmation from high-resolution follow-up studies, these could be the most metal-poor massive stars of the Local Group.

  13. Constructing a logical, regular axis topology from an irregular topology (United States)

    Faraj, Daniel A.


    Constructing a logical regular topology from an irregular topology including, for each axial dimension and recursively, for each compute node in a subcommunicator until returning to a first node: adding to a logical line of the axial dimension a neighbor specified in a nearest neighbor list; calling the added compute node; determining, by the called node, whether any neighbor in the node's nearest neighbor list is available to add to the logical line; if a neighbor in the called compute node's nearest neighbor list is available to add to the logical line, adding, by the called compute node to the logical line, any neighbor in the called compute node's nearest neighbor list for the axial dimension not already added to the logical line; and, if no neighbor in the called compute node's nearest neighbor list is available to add to the logical line, returning to the calling compute node.

  14. Manufacturing of Cast Metal Foams with Irregular Cell Structure

    Directory of Open Access Journals (Sweden)

    Kroupová I.


    Full Text Available Metallic foams are materials of which the research is still on-going, with the broad applicability in many different areas (e.g. automotive industry, building industry, medicine, etc.. These metallic materials have specific properties, such as large rigidity at low density, high thermal conductivity, capability to absorb energy, etc. The work is focused on the preparation of these materials using conventional casting technology (infiltration method, which ensures rapid and economically feasible method for production of shaped components. In the experimental part we studied conditions of casting of metallic foams with open pores and irregular cell structure made of ferrous and nonferrous alloys by use of various types of filler material (precursors.

  15. Global scale ionospheric irregularities associated with thunderstorm activity

    CERN Document Server

    Pulinets, S A


    The potential difference near 280 kV exists between ground and ionosphere. This potential difference is generated by thunderstorm discharges all over the world, and return current closes the circuit in the areas of fair weather (so-called fair weather current). The model calculations and experimental measurements clearly demonstrate non-uniform latitude-longitude distribution of electric field within the atmosphere. The recent calculations show that the strong large scale vertical atmospheric electric field can penetrate into the ionosphere and create large scale irregularities of the electron concentration. To check this the global distributions of thunderstorm activity obtained with the satellite monitoring for different seasons were compared with the global distributions of ionosphere critical frequency (which is equivalent to peak electron concentration) obtained with the help of satellite topside sounding. The similarity of the obtained global distributions clearly demonstrates the effects of thunderstor...

  16. Evaluation of Surface Slope Irregularity in Linear Parabolic Solar Collectors

    Directory of Open Access Journals (Sweden)

    F. Francini


    Full Text Available The paper describes a methodology, very simple in its application, for measuring surface irregularities of linear parabolic collectors. This technique was principally developed to be applied in cases where it is difficult to use cumbersome instruments and to facilitate logistic management. The instruments to be employed are a digital camera and a grating. If the reflector surface is defective, the image of the grating, reflected on the solar collector, appears distorted. Analyzing the reflected image, we can obtain the local slope of the defective surface. These profilometric tests are useful to identify and monitor the mirror portions under mechanical stress and to estimate the losses caused by the light rays deflected outside the absorber.

  17. The Orbits of Jupiter’s Irregular Satellites

    Energy Technology Data Exchange (ETDEWEB)

    Brozović, Marina; Jacobson, Robert A., E-mail:, E-mail: [Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, MS 301-120, Pasadena, CA 91109-8099 (United States)


    We report on the improved ephemerides for the irregular Jovian satellites. We used a combination of numerically integrated equations of motion and a weighted least-squares algorithm to fit the astrometric measurements. The orbital fits for 59 satellites are summarized in terms of state vectors, post-fit residuals, and mean orbital elements. The current data set appears to be sensitive to the mass of Himalia, which is constrained to the range of GM  = 0.13–0.28 km{sup 3} s{sup −2}. Here, GM is the product of the Newtonian constant of gravitation, G and the body's mass, M . Our analysis of the orbital uncertainties indicates that 11 out of 59 satellites are lost owing to short data arcs. The lost satellites hold provisional International Astronomical Union (IAU) designations and will likely need to be rediscovered.

  18. Combined radar observations of equatorial electrojet irregularities at Jicamarca

    Directory of Open Access Journals (Sweden)

    D. L. Hysell


    Full Text Available Daytime equatorial electrojet plasma irregularities were investigated using five distinct radar diagnostics at Jicamarca including range-time-intensity (RTI mapping, Faraday rotation, radar imaging, oblique scattering, and multiple-frequency scattering using the new AMISR prototype UHF radar. Data suggest the existence of plasma density striations separated by 3–5 km and propagating slowly downward. The striations may be caused by neutral atmospheric turbulence, and a possible scenario for their formation is discussed. The Doppler shifts of type 1 echoes observed at VHF and UHF frequencies are compared and interpreted in light of a model of Farley Buneman waves based on kinetic ions and fluid electrons with thermal effects included. Finally, the up-down and east-west asymmetries evident in the radar observations are described and quantified.

  19. Towards intrinsic magnetism of graphene sheets with irregular zigzag edges. (United States)

    Chen, Lianlian; Guo, Liwei; Li, Zhilin; Zhang, Han; Lin, Jingjing; Huang, Jiao; Jin, Shifeng; Chen, Xiaolong


    The magnetism of graphene has remained divergent and controversial due to absence of reliable experimental results. Here we show the intrinsic magnetism of graphene edge states revealed based on unidirectional aligned graphene sheets derived from completely carbonized SiC crystals. It is found that ferromagnetism, antiferromagnetism and diamagnetism along with a probable superconductivity exist in the graphene with irregular zigzag edges. A phase diagram is constructed to show the evolution of the magnetism. The ferromagnetic ordering curie-temperature of the fundamental magnetic order unit (FMOU) is 820 ± 80 K. The antiferromagnetic ordering Neel temperature of the FMOUs belonging to different sublattices is about 54 ± 2 K. The diamagnetism is similar to that of graphite and can be well described by the Kotosonov's equation. Our experimental results provide new evidences to clarify the controversial experimental phenomena observed in graphene and contribute to a deeper insight into the nature of magnetism in graphene based system.

  20. Comparison of different dose calculation methods for irregular photon fields

    International Nuclear Information System (INIS)

    Zakaria, G.A.; Schuette, W.


    In this work, 4 calculation methods (Wrede method, Clarskon method of sector integration, beam-zone method of Quast and pencil-beam method of Ahnesjoe) are introduced to calculate point doses in different irregular photon fields. The calculations cover a typical mantle field, an inverted Y-field and different blocked fields for 4 and 10 MV photon energies. The results are compared to those of measurements in a water phantom. The Clarkson and the pencil-beam method have been proved to be the methods of equal standard in relation to accuracy. Both of these methods are being distinguished by minimum deviations and applied in our clinical routine work. The Wrede and beam-zone methods deliver useful results to central beam and yet provide larger deviations in calculating points beyond the central axis. (orig.) [de

  1. Global scale ionospheric irregularities associated with thunderstorm activity

    International Nuclear Information System (INIS)

    Pulinets, Sergey A.; Depuev, Victor H.


    The potential difference near 280 kV exists between ground and ionosphere. This potential difference is generated by thunderstorm discharges all over the world, and return current closes the circuit in the areas of fair weather (so-called fair weather current). The model calculations and experimental measurements clearly demonstrate non-uniform latitude-longitude distribution of electric field within the atmosphere. The recent calculations show that the strong large scale vertical atmospheric electric field can penetrate into the ionosphere and create large scale irregularities of the electron concentration. To check this the global distributions of thunderstorm activity obtained with the satellite monitoring for different seasons were compared with the global distributions of ionosphere critical frequency (which is equivalent to peak electron concentration) obtained with the help of satellite topside sounding. The similarity of the obtained global distributions clearly demonstrates the effects of thunderstorm electric fields onto the Earth's ionosphere. (author)

  2. Irregular Corneas: Improve Visual Function With Scleral Contact Lenses. (United States)

    de Luis Eguileor, Beatriz; Etxebarria Ecenarro, Jaime; Santamaria Carro, Alaitz; Feijoo Lera, Raquel


    To assess visual function in patients with irregular cornea who do not tolerate gas permeable (GP) corneal contact lenses and are fitted with GP scleral contact lenses (Rose K2 XL). In this prospective study, we analyzed 15 eyes of 15 patients who did not tolerate GP corneal contact lenses and were fitted with scleral contact lenses (Rose K2 XL). We assessed visual function using visual acuity and the visual function index (VF-14); we used the VF-14 as an indicator of patient satisfaction. The measurements were taken with the optical correction used before and 1 month after the fitting of the Rose K2 XL contact lenses. We also recorded the number of hours lenses had been worn over the first month. Using Rose K2 XL contact lenses, visual acuity was 0.06±0.07 logMAR. In all cases, visual acuity had improved compared with the measurement before fitting the lenses (0.31±0.18 logMAR; P=0.001). VF-14 scores were 72.74±12.38 before fitting of the scleral lenses, and 89.31±10.87 after 1 month of lens use (P=0.003). Patients used these scleral lenses for 9.33±2.99 comfortable hours of wear. Both visual acuity and VF-14 may improve after fitting Rose K2 XL contact lenses in patients with irregular corneas. In addition, in our patients, these lenses can be worn for a longer period than GP corneal contact lenses.

  3. Reproducibility of irregular radiation fields for malignant lymphoma

    International Nuclear Information System (INIS)

    Mock, U.; Dieckmann, K.; Poetter, R.; Molitor, A.M.; Haverkamp, U.


    Purpose: Radiation treatment for malignant lymphoma requires large field irradiation with irregular blocks according to the individual anatomy and tumor configuration. For determination of safety margins (PTV) we quantitatively analysed the accuracy of field and block placement with regard to different anatomical regions. Patients and Methods: Forty patients with malignant lymphoma were irradiated using the classical supra-/infradiaphragmatic field arrangements. Treatment was performed with 10-MeV photons and irregularly shaped, large opposing fields. We evaluated the accuracy of field and block placements during the treatment courses by comparing the regularly performed verification - with the simulation films. Deviations were determined with respect to the field edges and the central axis, along the x- and z-axis. Results: With regard to the field edges, mean deviations of 2.0 mm and 3.4 mm were found along the x- and z-axis. The corresponding standard deviations were 3.4 mm and 5.5 mm, respectively. With regard to the shielding blocks, mean displacement along the x- and z-axis was 2.2 mm and 3.8 mm. In addition, overall standard deviations of 5.7 mm (x-axis) and 7.1 mm (z-axis) were determined. During the course of time an improved accuracy of block placement was notable. Conclusion: Systematic analysis of port films gives information for a better defining safety margins in external radiotherapy. Evaluation of verification films on a regular basis improves set-up accuracy by reducing displacements. (orig.) [de

  4. Volume determination of irregularly-shaped quasi-spherical nanoparticles. (United States)

    Attota, Ravi Kiran; Liu, Eileen Cherry


    Nanoparticles (NPs) are widely used in diverse application areas, such as medicine, engineering, and cosmetics. The size (or volume) of NPs is one of the most important parameters for their successful application. It is relatively straightforward to determine the volume of regular NPs such as spheres and cubes from a one-dimensional or two-dimensional measurement. However, due to the three-dimensional nature of NPs, it is challenging to determine the proper physical size of many types of regularly and irregularly-shaped quasi-spherical NPs at high-throughput using a single tool. Here, we present a relatively simple method that determines a better volume estimate of NPs by combining measurements from their top-down projection areas and peak heights using two tools. The proposed method is significantly faster and more economical than the electron tomography method. We demonstrate the improved accuracy of the combined method over scanning electron microscopy (SEM) or atomic force microscopy (AFM) alone by using modeling, simulations, and measurements. This study also exposes the existence of inherent measurement biases for both SEM and AFM, which usually produce larger measured diameters with SEM than with AFM. However, in some cases SEM measured diameters appear to have less error compared to AFM measured diameters, especially for widely used IS-NPs such as of gold, and silver. The method provides a much needed, proper high-throughput volumetric measurement method useful for many applications. Graphical Abstract The combined method for volume determination of irregularly-shaped quasi-spherical nanoparticles.

  5. Efficient Clustering for Irregular Geometries Based on Identification of Concavities

    Directory of Open Access Journals (Sweden)

    Velázquez-Villegas Fernando


    Full Text Available Two dimensional clustering problem has much relevance in applications related to the efficient use of raw material, such as cutting stock, packing, etc. This is a very complex problem in which multiple bodies are accommodated efficiently in a way that they occupy as little space as possible. The complexity of the problem increases with the complexity of the bodies. Clearly the number of possible arrangements between bodies is huge. No Fit Polygon (NFP allows to determine the entire relative positions between two patterns (regular or irregular in contact, non-overlapping, therefore the best position can be selected. However, NFP generation requires a lot of calculations; besides, selecting the best cluster isn’t a simple task because, between two irregular patterns in contact, hollows (unusable areas and external concavities (usable areas can be produced. This work presents a quick and simple method to reduce calculations associated with NFP generation and to minimize unusable areas in a cluster. This method consists of generating partial NFP, just on concave regions of the patterns, and selecting the best cluster using a total weighted efficiency, i.e. a weighted value of enclosure efficiency (ratio of occupied area on convex hull area and hollow efficiency (ratio of occupied area on cluster area. The proposed method produces similar results as those obtained by other methods; however the shape of the clusters obtained allows to accommodate more parts in similar spaces, which is a desirable result when it comes to optimizing the use of material. We present two examples to show the performance of the proposal.

  6. [Screening analysis of irregular antibodies from random donor population in Shaoguan area]. (United States)

    Zhu, Jian-Ying; Lan, Jiong-Cai; Luo, Hong-Qing


    The study was purposed to analyze the frequency and distribution of irregular antibodies in Shaoguan area. Screening 15 033 random donor antibodies in Shaoguan area by screening cells, polybrene and antiglobulin tests. The results indicated that the irregular antibodies were found in 42 samples. The frequency of irregular antibodies in female was higher than that in male (P antibodies such as anti-D, anti-E, and anti-Ec C were common (47.6%). 2 samples of Le antibodies were failed to be found by polybrene test. 2 samples of irregular antibodies with titer 2 were undiscovered by screening test of 10 pooled samples. In conclusion, because of irregular antibodies resulting in hemolytic transfusion reaction, the investigation of frequency and distribution of irregular antibodies is very important for safe transfusion. Antibody screening must be done for female donors, and especially for massive plasma transfusion of patients with severe and dangerous illness and infants so as to ensure safety.

  7. Experimental investigation of coolability behaviour of irregularly shaped particulate debris bed

    International Nuclear Information System (INIS)

    Kulkarni, P.P.; Rashid, M.; Kulenovic, R.; Nayak, A.K.


    In case of a severe nuclear reactor accident, the core can melt and form a particulate debris bed in the lower plenum of the reactor pressure vessel (RPV). Due to the decay heat, the particle bed, if not cooled properly, can cause failure of the RPV. In order to avoid further propagation of the accident, complete coolability of the debris bed is necessary. For that, understanding of various phenomena taking place during the quenching is important. In the frame of the reactor safety research, fundamental experiments on the coolability of debris beds are carried out at IKE with the test facility 'DEBRIS'. In the present paper, the boiling and dry-out experimental results on a particle bed with irregularly shaped particles mixed with stainless steel balls have been reported. The pressure drops and dry-out heat fluxes of the irregular-particle bed are very similar to those for the single-sized 3 mm spheres bed, despite the fact that the irregular-particle bed is composed of particles with equivalent diameters ranging from 2 to 10 mm. Under top-flooding conditions, the pressure gradients are all smaller than the hydrostatic pressure gradient of water, indicating an important role of the counter-current interfacial drag force. For bottom-flooding with a liquid inflow velocity higher than about 2.7 mm/s, the pressure gradient generally increases consistently with the vapour velocity and the fluid-particle drag becomes important. The system pressures (1 and 3 bar) have negligible effects on qualitative behaviour of the pressure gradients. The coolability of debris beds is mainly limited by the counter-current flooding limit (CCFL) even under bottom-flooding conditions with low flow rates. The system pressure and the flow rate are found to have a distinct effect on the dry-out heat flux. Different classical models have been used to predict the pressure drop characteristics and the dry-out heat flux (DHF). Comparisons are made among the models and experimental results for

  8. Parametric pitch instability investigation of Deep Draft Semi-submersible platform in irregular waves


    Huan Mao; Hezhen Yang


    Parametric pitch instability of a Deep Draft Semi-submersible platform (DDS) is investigated in irregular waves. Parametric pitch is a form of parametric instability, which occurs when parameters of a system vary with time and the variation satisfies a certain condition. In previous studies, analyzing of parametric instability is mainly limited to regular waves, whereas the realistic sea conditions are irregular waves. Besides, parametric instability also occurs in irregular waves in some exp...

  9. Socio-technical transition as a co-evolutionary process: Innovation and the role of niche markets in the transition to motor vehicles (United States)

    Birky, Alicia K.


    Significant reductions in greenhouse emissions from personal transportation will require a transition to an alternative technology regime based on renewable energy sources. Two bodies of research, the quasi-evolutionary (QE) model and the multi-level perspective (MLP) assert that processes within niches play a fundamental role in such transitions. This research asks whether the description of transitions based on this niche hypothesis and its underlying assumptions is consistent with the historical U.S. transition to motor vehicles at the beginning of the 20th century. Unique to this dissertation is the combination of the perspective of the entrepreneur with co-evolutionary approaches to socio-technical transitions. This approach is augmented with concepts from the industry life-cycle model and with a taxonomy of mechanisms of learning. Using this analytic framework, I examine specifically the role of entrepreneurial behavior and processes within and among firms in the co-evolution of technologies and institutions during the transition to motor vehicles. I find that niche markets played an important role in the development of the technology, institutions, and the industry. However, I also find that the diffusion of the automobile is not consistent with the niche hypothesis in the following ways: (1) product improvements and cost reductions were not realized in niche markets, but were achieved simultaneously with diffusion into mass markets; (2) in addition to learning-by-doing and learning-by-interacting with users, knowledge spillovers and interacting with suppliers were critical in this process; (3) cost reductions were not automatic results of expanding markets, but rather arose from the strategies of entrepreneurs based on personal perspectives and values. This finding supports the use of a behavioral approach with a micro-focus in the analysis of socio-technical change. I also find that the emergence and diffusion of the motor vehicle can only be understood by

  10. Eastern European Irregular Troops in the XVIII Century: Crisis and Evolution

    Directory of Open Access Journals (Sweden)

    Artyom Y. Peretyatko


    Full Text Available The article is devoted to the evolution of Eastern European irregular troops in the XVIII century, when they were forced to compete with the regular armies of the Western European model. In it are analyzed shortcomings and advantages of irregular system of the organization which became actual in this century. The author comes to a conclusion that the elimination of the most part of the East European irregular troops was made possible only when regular armies start using their tactics and weapons. Similar influence was mutual, and preserved irregular troops adopted more and more elements of the organization of a regular army.

  11. High attack rate for malaria through irregular migration routes to a country on verge of elimination. (United States)

    Wickramage, Kolitha; Premaratne, Risintha G; Peiris, Sharika L; Mosca, Davide


    Irregular migration in the form of human smuggling and human trafficking is recognized as a global public health issue. Thirty-two cases of Plasmodium falciparum were detected in 534 irregular migrants returning to Sri Lanka via failed human smuggling routes from West Africa in 2012, contributing to the largest burden of imported cases in Sri Lanka as it entered elimination phase. Beyond the criminality and human rights abuse, irregular migration plays an important, but often forgotten, pathway for malaria re-introduction. Active surveillance of the growing numbers of irregular migrant flows becomes an important strategy as Sri Lanka advances towards goals of malaria elimination.

  12. Irregular Saturnian Moon Lightcurves from Cassini-ISS Observations: Update (United States)

    Denk, Tilmann; Mottola, S.


    Cassini ISS-NAC observations of the irregular moons of Saturn revealed various physical information on these objects. 16 synodic rotational periods: Hati (S43): 5.45 h; Mundilfari (S25): 6.74 h; Suttungr (S23): ~7.4 h; Kari (S45): 7.70 h; Siarnaq (S29): 10.14 h; Tarvos (S21): 10.66 h; Ymir (S19, sidereal period): 11.92220 h ± 0.1 s; Skathi (S27): ~12 h; Hyrrokkin (S44): 12.76 h; Ijiraq (S22): 13.03 h; Albiorix (S26): 13.32 h; Bestla (S39): 14.64 h; Bebhionn (S37): ~15.8 h; Kiviuq (S24): 21.82 h; Thrymr (S30): ~27 h; Erriapus (S28): ~28 h. The average period for the prograde-orbiting moons is ~16 h, for the retrograde moons ~11½ h (includes Phoebe's 9.2735 h from Bauer et al., AJ, 2004). Phase-angle dependent behavior of lightcurves: The phase angles of the observations range from 2° to 105°. The lightcurves which were obtained at low phase (<40°) show the 2-maxima/ 2-minima pattern expected for this kind of objects. At higher phases, more complicated lightcurves emerge, giving rough indications on shapes. Ymir pole and shape: For satellite Ymir, a convex-hull shape model and the pole-axis orientation have been derived. Ymir's north pole points toward λ = 230°±180°, β = -85°±10°, or RA = 100°±20°, Dec = -70°±10°. This is anti-parallel to the rotation axes of the major planets, indicating that Ymir not just orbits, but also rotates in a retrograde sense. The shape of Ymir resembles a triangular prism with edge lengths of ~20, ~24, and ~25 km. The ratio between the longest 25 km) and shortest axis (pole axis, ~15 km) is ~1.7. Erriapus seasons: The pole direction of object Erriapus has probably a low ecliptic latitude. This gives this moon seasons similar to the Uranian regular moons with periods where the sun stands very high in the sky over many years, and with years-long periods of permanent night. Hati density: The rotational frequency of the fastest rotator (Hati) is close to the frequency where the object would lose material from the surface if

  13. Extended Schmidt law holds for faint dwarf irregular galaxies (United States)

    Roychowdhury, Sambit; Chengalur, Jayaram N.; Shi, Yong


    Context. The extended Schmidt law (ESL) is a variant of the Schmidt which relates the surface densities of gas and star formation, with the surface density of stellar mass added as an extra parameter. Although ESL has been shown to be valid for a wide range of galaxy properties, its validity in low-metallicity galaxies has not been comprehensively tested. This is important because metallicity affects the crucial atomic-to-molecular transition step in the process of conversion of gas to stars. Aims: We empirically investigate for the first time whether low metallicity faint dwarf irregular galaxies (dIrrs) from the local universe follow the ESL. Here we consider the "global" law where surface densities are averaged over the galactic discs. dIrrs are unique not only because they are at the lowest end of mass and star formation scales for galaxies, but also because they are metal-poor compared to the general population of galaxies. Methods: Our sample is drawn from the Faint Irregular Galaxy GMRT Survey (FIGGS) which is the largest survey of atomic hydrogen in such galaxies. The gas surface densities are determined using their atomic hydrogen content. The star formation rates are calculated using GALEX far ultraviolet fluxes after correcting for dust extinction, whereas the stellar surface densities are calculated using Spitzer 3.6 μm fluxes. The surface densities are calculated over the stellar discs defined by the 3.6 μm images. Results: We find dIrrs indeed follow the ESL. The mean deviation of the FIGGS galaxies from the relation is 0.01 dex, with a scatter around the relation of less than half that seen in the original relation. In comparison, we also show that the FIGGS galaxies are much more deviant when compared to the "canonical" Kennicutt-Schmidt relation. Conclusions: Our results help strengthen the universality of the ESL, especially for galaxies with low metallicities. We suggest that models of star formation in which feedback from previous generations

  14. Irregular persistent activity induced by synaptic excitatory feedback

    Directory of Open Access Journals (Sweden)

    Francesca Barbieri


    Full Text Available Neurophysiological experiments on monkeys have reported highly irregular persistent activity during the performance of an oculomotor delayed-response task. These experiments show that during the delay period the coefficient of variation (CV of interspike intervals (ISI of prefrontal neurons is above 1, on average, and larger than during the fixation period. In the present paper, we show that this feature can be reproduced in a network in which persistent activity is induced by excitatory feedback, provided that (i the post-spike reset is close enough to threshold , (ii synaptic efficacies are a non-linear function of the pre-synaptic firing rate. Non-linearity between presynaptic rate and effective synaptic strength is implemented by a standard short-term depression mechanism (STD. First, we consider the simplest possible network with excitatory feedback: a fully connected homogeneous network of excitatory leaky integrate-and-fire neurons, using both numerical simulations and analytical techniques. The results are then confirmed in a network with selective excitatory neurons and inhibition. In both the cases there is a large range of values of the synaptic efficacies for which the statistics of firing of single cells is similar to experimental data.

  15. Timing irregularities of PSR J1705-1906 (United States)

    Liu, Y. L.; Yuan, J. P.; Wang, J. B.; Liu, X. W.; Wang, N.; Yuen, R.


    Timing analysis of PSR J1705-1906 using data from Nanshan 25-m and Parkes 64-m radio telescopes, which span over fourteen years, shows that the pulsar exhibits significant proper motion, and rotation instability. We updated the astrometry parameters and the spin parameters of the pulsar. In order to minimize the effect of timing irregularities on measuring its position, we employ the Cholesky method to analyse the timing noise. We obtain the proper motion of -77(3) mas yr-1 in right ascension and -38(29) mas yr-1 in declination. The power spectrum of timing noise is analyzed for the first time, which gives the spectral exponent α =-5.2 for the power-law model indicating that the fluctuations in spin frequency and spin-down rate dominate the red noise. We detect two small glitches from this pulsar with fractional jump in spin frequency of Δ ν /ν ˜ 2.9 × 10^{-10} around MJD 55199 and Δ ν /ν ˜ 2.7× 10^{-10} around MJD 55953. Investigations of pulse profile at different time segments suggest no significant changes in the pulse profiles around the two glitches.

  16. Irregular brood patterns and worker reproduction in social wasps. (United States)

    Kovacs, Jennifer L; Goodisman, Michael A D


    The potential for reproductive conflict among colony members exists in all social insect societies. For example, queens and workers may be in conflict over the production of males within colonies. Kin selection theory predicts that in a colony headed by a multiply-mated queen, worker reproduction is prevented by worker policing in the form of differential oophagy. However, few studies have demonstrated that workers actually lay eggs within queenright colonies. The purpose of this study was to determine if workers laid male eggs within unmanipulated queen-right colonies of the polyandrous social wasps Vespula maculifrons and V. squamosa. We focused our analysis on an unusual brood pattern within colonies, multiple egg cells. We were primarily interested in determining if individuals reared in these irregular circumstances were queen or worker offspring. To address this question, we genotyped 318 eggs from eight V. maculifrons and two V. squamosa colonies. No worker reproduction was detected in any of the queenright colonies; all of the eggs found in multiple egg cells were consistent with being queen-produced. However, the frequency of multiple egg cells differed among colonies, suggesting that queens vary in the frequency of errors they make when laying eggs within cells. Finally, we suggest that workers may not be laying eggs within queenright colonies and that worker reproduction may be controlled through mechanisms other than differential oophagy in polyandrous Vespula wasps.

  17. Representation and Reconconstruction of Triangular Irregular Networks with Vertical Walls (United States)

    Gorte, B.; Lesparre, J.


    Point clouds obtained by aerial laser scanning are a convenient input source for high resolution 2.5d elevation models, such as the Dutch AHN-2. More challenging is the fully automatic reconstruction of 3d city models. An actual demand for a combined 2.5d terrain and 3d city model for an urban hydrology application led to the design of an extension to the well-known Delaunay triangulated irregular networks (TINs) as to accommodate vertical walls. In addition we introduce methods to generate and refine models adhering to our data structure. These are based on combining two approaches: a representation of the TIN using stars of vertices and triangles, together with segmenting the TIN on the basis of coplanarity of adjacent triangles. The approach is supposed to deliver the complete model including walls at the correct locations, without relying on additional map data, as these often lack completeness, actuality and accuracy, and moreover most of the time do not account for parts facades not going down to street level. However, automatic detection of height discontinuities to obtain the exact location of the walls is currently still under implementation.


    Energy Technology Data Exchange (ETDEWEB)

    Elmegreen, Bruce G., E-mail: [IBM Research Division, T.J. Watson Research Center, 1101 Kitchawan Road, Yorktown Heights, NY 10598 (United States)


    A dynamical model for star formation on a galactic scale is proposed in which the interstellar medium is constantly condensing to star-forming clouds on the dynamical time of the average midplane density, and the clouds are constantly being disrupted on the dynamical timescale appropriate for their higher density. In this model, the areal star formation rate scales with the 1.5 power of the total gas column density throughout the main regions of spiral galaxies, and with a steeper power, 2, in the far outer regions and in dwarf irregular galaxies because of the flaring disks. At the same time, there is a molecular star formation law that is linear in the main and outer parts of disks and in dIrrs because the duration of individual structures in the molecular phase is also the dynamical timescale, canceling the additional 0.5 power of surface density. The total gas consumption time scales directly with the midplane dynamical time, quenching star formation in the inner regions if there is no accretion, and sustaining star formation for ∼100 Gyr or more in the outer regions with no qualitative change in gas stability or molecular cloud properties. The ULIRG track follows from high densities in galaxy collisions.

  19. Metallicity of Young and Old Stars in Irregular Galaxies (United States)

    Tikhonov, N. A.


    Based on archived images obtained with the Hubble Space Telescope, stellar photometry for 105 irregular galaxies has been conducted. We have shown the red supergiant and giant branches in the obtained Hertzsprung-Russel diagrams. Using the TRGB method, distances to galaxies and metallicity of red giants have been determined. The color index ( V - I) of the supergiant branch at the luminosity level M I = -7 was chosen as the metallicity index of red supergiants. For the galaxies under study, the diagrams have been built, in which the correlation can be seen between the luminosity of galaxies ( M B ) and metallicity of red giants and supergiants. The main source of variance of the results in the obtained diagrams is, in our opinion, uncertainty inmeasurements of galaxy luminosities and star-forming outburst. The relation between metallicity of young and old stars shows that main enrichment of galaxies with metals has taken place in the remote past. Deviations of some galaxies in the obtained relation can possibly be explained with the fall of the intergalactic gas on them, although, this inconsiderably affects metallicities of the stellar content.

  20. Climatic irregular staircases: generalized acceleration of global warming. (United States)

    De Saedeleer, Bernard


    Global warming rates mentioned in the literature are often restricted to a couple of arbitrary periods of time, or of isolated values of the starting year, lacking a global view. In this study, we perform on the contrary an exhaustive parametric analysis of the NASA GISS LOTI data, and also of the HadCRUT4 data. The starting year systematically varies between 1880 and 2002, and the averaging period from 5 to 30 yr - not only decades; the ending year also varies . In this way, we uncover a whole unexplored space of values for the global warming rate, and access the full picture. Additionally, stairstep averaging and linear least squares fitting to determine climatic trends have been sofar exclusive. We propose here an original hybrid method which combines both approaches in order to derive a new type of climatic trend. We find that there is an overall acceleration of the global warming whatever the value of the averaging period, and that 99.9% of the 3029 Earth's climatic irregular staircases are rising. Graphical evidence is also given that choosing an El Niño year as starting year gives lower global warming rates - except if there is a volcanic cooling in parallel. Our rates agree and generalize several results mentioned in the literature.

  1. Image fusion and enhancement using triangulated irregular networks (United States)

    Scarmana, G.


    A triangulated irregular network (TIN) is a viable structure for vector representation of raster image data. To visualize the image characterized by triangulation, it is required to fit a continuous surface of pixel brightness values in the triangulation (i.e. to interpolate data stored in its vertices). From this perspective, this paper presents a multi-frame image fusion and enhancement process that employs TIN structures rather than arrays of pixels as the original working units. The feasibility of this application relates to the fact that a TIN model offers a good quality digital image representation with a reduced density of pixel values as compared to a corresponding raster representation [4]. In the proposed process several low-resolution unregistered and compressed images (such as those extracted from a video footage) of a common scene are: (a) registered to a sub-pixel level (b) transformed to a TIN structure, (c) grouped or mapped globally within a singular framework to create a denser TIN composite, and (d) the TIN representation is used in reverse to reconstruct a higher resolution image in raster format with more details than any of the original input frames. Tests and subsequent results are shown to demonstrate the validity and accuracy of the proposed multi-frame image enhancement process. A comparison of this process of multi-frame image enhancement using various interpolation methods and practices is included.


    Energy Technology Data Exchange (ETDEWEB)

    Elmegreen, Bruce G. [IBM Research Division, T.J. Watson Research Center, 1101 Kitchawan Road, Yorktown Heights, NY 10598 (United States); Hunter, Deidre A., E-mail:, E-mail: [Lowell Observatory, 1400 West Mars Hill Road, Flagstaff, Arizona 86001 (United States)


    The radial profiles of gas, stars, and far-ultraviolet radiation in 20 dwarf Irregular galaxies are converted to stability parameters and scale heights for a test of the importance of two-dimensional (2D) instabilities in promoting star formation. A detailed model of this instability involving gaseous and stellar fluids with self-consistent thicknesses and energy dissipation on a perturbation crossing time gives the unstable growth rates. We find that all locations are effectively stable to 2D perturbations, mostly because the disks are thick. We then consider the average volume densities in the midplanes, evaluated from the observed H i surface densities and calculated scale heights. The radial profiles of the star-formation rates are equal to about 1% of the H i surface densities divided by the free fall times at the average midplane densities. This 1% resembles the efficiency per unit free fall time commonly found in other cases. There is a further variation of this efficiency with radius in all of our galaxies, following the exponential disk with a scale length equal to about twice the stellar mass scale length. This additional variation is modeled by the molecular fraction in a diffuse medium using radiative transfer solutions for galaxies with the observed dimensions and properties of our sample. We conclude that star formation is activated by a combination of three-dimensional gaseous gravitational processes and molecule formation. Implications for outer disk structure and formation are discussed.

  3. Weighted statistical parameters for irregularly sampled time series (United States)

    Rimoldini, Lorenzo


    Unevenly spaced time series are common in astronomy because of the day-night cycle, weather conditions, dependence on the source position in the sky, allocated telescope time and corrupt measurements, for example, or inherent to the scanning law of satellites like Hipparcos and the forthcoming Gaia. Irregular sampling often causes clumps of measurements and gaps with no data which can severely disrupt the values of estimators. This paper aims at improving the accuracy of common statistical parameters when linear interpolation (in time or phase) can be considered an acceptable approximation of a deterministic signal. A pragmatic solution is formulated in terms of a simple weighting scheme, adapting to the sampling density and noise level, applicable to large data volumes at minimal computational cost. Tests on time series from the Hipparcos periodic catalogue led to significant improvements in the overall accuracy and precision of the estimators with respect to the unweighted counterparts and those weighted by inverse-squared uncertainties. Automated classification procedures employing statistical parameters weighted by the suggested scheme confirmed the benefits of the improved input attributes. The classification of eclipsing binaries, Mira, RR Lyrae, Delta Cephei and Alpha2 Canum Venaticorum stars employing exclusively weighted descriptive statistics achieved an overall accuracy of 92 per cent, about 6 per cent higher than with unweighted estimators.

  4. Irregular treatment of hypertension in the former Soviet Union. (United States)

    Roberts, Bayard; Stickley, Andrew; Balabanova, Dina; McKee, Martin


    The USSR failed to establish a modern pharmaceutical industry and lacked the capacity for reliable distribution of drugs. Patients were required to pay for outpatient drugs and the successor states have inherited this legacy, so that those requiring long-term treatment face considerable barriers in receiving it. It was hypothesised that citizens of former Soviet republics requiring treatment for hypertension may not be receiving regular treatment. To describe the regularity of treatment among those diagnosed with hypertension and prescribed treatment in eight countries of the former Soviet Union, and explore which factors are associated with not taking medication regularly. Using data from over 18 000 respondents from eight former Soviet countries, individuals who had been told that they had hypertension by a health professional and prescribed treatment were identified. By means of multivariate logistic analysis the characteristics of those taking treatment daily and less than daily were compared. Only 26% of those prescribed treatment took it daily. The probability of doing so varied among countries and was highest in Russia, Belarus and Georgia, and lowest in Armenia (although Georgia's apparent advantage may reflect low rates of diagnosis). Women, older people, those living in urban areas, and non-smokers and non-drinkers were more likely to take treatment daily. A high proportion of those who have been identified by health professionals as requiring hypertension treatment are not taking it daily. These findings suggest that irregular hypertension treatment is a major problem in this region and will require an urgent response.

  5. Influence of Ionospheric Irregularities on GNSS Remote Sensing

    Directory of Open Access Journals (Sweden)

    M. V. Tinin


    Full Text Available We have used numerical simulation to study the effects of ionospheric irregularities on accuracy of global navigation satellite system (GNSS measurements, using ionosphere-free (in atmospheric research and geometry-free (in ionospheric research dual-frequency phase combinations. It is known that elimination of these effects from multifrequency GNSS measurements is handi-capped by diffraction effects during signal propagation through turbulent ionospheric plasma with the inner scale being smaller than the Fresnel radius. We demonstrated the possibility of reducing the residual ionospheric error in dual-frequency GNSS remote sensing in ionosphere-free combination by Fresnel inversion. The inversion parameter, the distance to the virtual screen, may be selected from the minimum of amplitude fluctuations. This suggests the possibility of improving the accuracy of GNSS remote sensing in meteorology. In the study of ionospheric disturbances with the aid of geometry-free combination, the Fresnel inversion eliminates only the third-order error. To eliminate the random TEC component which, like the measured average TEC, is the first-order correction, we should use temporal filtering (averaging.

  6. Mechanically Milled Irregular Zinc Nanoparticles for Printable Bioresorbable Electronics. (United States)

    Mahajan, Bikram K; Yu, Xiaowei; Shou, Wan; Pan, Heng; Huang, Xian


    Bioresorbable electronics is predominantly realized by complex and time-consuming anhydrous fabrication processes. New technology explores printable methods using inks containing micro- or nano-bioresorbable particles (e.g., Zn and Mg). However, these particles have seldom been obtained in the context of bioresorbable electronics using cheap, reliable, and effective approaches with limited study on properties essential to printable electronics. Here, irregular nanocrystalline Zn with controllable sizes and optimized electrical performance is obtained through ball milling approach using polyvinylpyrrolidone (PVP) as a process control agent to stabilize Zn particles and prevent cold welding. Time and PVP dependence of the ball milled particles are studied with systematic characterizations of morphology and composition of the nanoparticles. The results reveal crystallized Zn nanoparticles with a size of ≈34.834 ± 1.76 nm and low surface oxidation. The resulting Zn nanoparticles can be readily printed onto bioresorbable substrates and sintered at room temperature using a photonic sintering approach, leading to a high conductivity of 44 643 S m -1 for printable zinc nanoparticles. The techniques to obtain Zn nanoparticles through ball milling and processing them through photonic sintering may potentially lead to a mass fabrication method for bioresorbable electronics and promote its applications in healthcare, environmental protection, and consumer electronics. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  7. Parametric pitch instability investigation of Deep Draft Semi-submersible platform in irregular waves

    Directory of Open Access Journals (Sweden)

    Huan Mao


    Full Text Available Parametric pitch instability of a Deep Draft Semi-submersible platform (DDS is investigated in irregular waves. Parametric pitch is a form of parametric instability, which occurs when parameters of a system vary with time and the variation satisfies a certain condition. In previous studies, analyzing of parametric instability is mainly limited to regular waves, whereas the realistic sea conditions are irregular waves. Besides, parametric instability also occurs in irregular waves in some experiments. This study predicts parametric pitch of a Deep Draft Semi-submersible platform in irregular waves. Heave motion of DDS is simulated by wave spectrum and response amplitude operator (RAO. Then Hill equation for DDS pitch motion in irregular waves is derived based on linear-wave theory. By using Bubnov-Galerkin approach to solve Hill equation, the corresponding stability chart is obtained. The differences between regular-waves stability chart and irregular-waves stability chart are compared. Then the sensitivity of wave parameters on DDS parametric pitch in irregular waves is discussed. Based on the discussion, some suggestions for the DDS design are proposed to avoid parametric pitch by choosing appropriate parameters. The results indicate that it's important and necessary to predict DDS parametric pitch in irregular waves during design process.

  8. Breaking Down Anonymity: Digital surveillance on irregular migrants in Germany and the Netherlands

    NARCIS (Netherlands)

    D.W.J. Broeders (Dennis)


    textabstractThe presence of irregular migrants causes a tough problem for policy makers. Political and popular aversion against the presence of irregular migrants has mounted in most West-European societies for years, yet their presence remains. Their exact numbers are obviously unknown - only

  9. Influence of initial stress, irregularity and heterogeneity on Love-type ...

    Indian Academy of Sciences (India)

    The present paper deals with the propagation of Love-type wave in an initially stressed irregular vertically heterogeneous layer lying over ... The effect of size and shape of irregularity, horizontal compressive initial stress, horizontal tensile initial stress, heterogeneity of the ...... University Press, Cambridge. Kaur T, Singh A K, ...

  10. On the Distinction between Regular and Irregular Inflectional Morphology: Evidence from Dinka (United States)

    Ladd, D. Robert; Remijsen, Bert; Manyang, Caguor Adong


    Discussions of the psycholinguistic significance of regularity in inflectional morphology generally deal with languages in which regular forms can be clearly identified and revolve around whether there are distinct processing mechanisms for regular and irregular forms. We present a detailed description of Dinka's notoriously irregular noun number…

  11. Lateralized effects of orthographical irregularity and auditory memory load on the kinematics of transciption typewriting

    NARCIS (Netherlands)

    Bloemsaat, J.G.; Galen, G.P. van; Meulenbroek, R.G.J.


    This study investigated the combined effects of orthographical irregularity and auditory memory load on the kinematics of finger movements in a transcription-typewriting task. Eight right-handed touch-typists were asked to type 80 strings of ten seven-letter words. In half the trials an irregularly

  12. Spectral classification of medium-scale high-latitude F region plasma density irregularities

    International Nuclear Information System (INIS)

    Singh, M.; Rodriguez, P.; Szuszczewicz, E.P.; Sachs Freeman Associates, Bowie, MD)


    The high-latitude ionosphere represents a highly structured plasma. Rodriguez and Szuszczewicz (1984) reported a wide range of plasma density irregularities (150 km to 75 m) at high latitudes near 200 km. They have shown that the small-scale irregularities (7.5 km to 75 m) populated the dayside oval more often than the other phenomenological regions. It was suggested that in the lower F region the chemical recombination is fast enough to remove small-scale irregularities before convection can transport them large distances, leaving structured particle precipitation as the dominant source term for irregularities. The present paper provides the results of spectral analyses of pulsed plasma probe data collected in situ aboard the STP/S3-4 satellite during the period March-September 1978. A quantitative description of irregularity spectra in the high-latitude lower F region plasma density is given. 22 references

  13. Shear Wave Propagation in Multilayered Medium including an Irregular Fluid Saturated Porous Stratum with Rigid Boundary

    Directory of Open Access Journals (Sweden)

    Ravinder Kumar


    Full Text Available The present investigation is concerned with the study of propagation of shear waves in an anisotropic fluid saturated porous layer over a semi-infinite homogeneous elastic half-space lying under an elastic homogeneous layer with irregularity present at the interface with rigid boundary. The rectangular irregularity has been taken in the half-space. The dispersion equation for shear waves is derived by using the perturbation technique followed by Fourier transformation. Numerically, the effect of irregularity present is analysed. It is seen that the phase velocity is significantly influenced by the wave number and the depth of the irregularity. The variations of dimensionless phase velocity against dimensionless wave number are shown graphically for the different size of rectangular irregularities with the help of MATLAB.

  14. New Opportunities for Remote Sensing Ionospheric Irregularities by Fitting Scintillation Spectra (United States)

    Carrano, C. S.; Rino, C. L.; Groves, K. M.


    In a recent paper, we presented a phase screen theory for the spectrum of intensity scintillations when the refractive index irregularities follow a two-component power law [Carrano and Rino, DOI: 10.1002/2015RS005903]. More recently we have investigated the inverse problem, whereby phase screen parameters are inferred from scintillation time series. This is accomplished by fitting the spectrum of intensity fluctuations with a parametrized theoretical model using Maximum Likelihood (ML) methods. The Markov-Chain Monte-Carlo technique provides a-posteriori errors and confidence intervals. The Akaike Information Criterion (AIC) provides justification for the use of one- or two-component irregularity models. We refer to this fitting as Irregularity Parameter Estimation (IPE) since it provides a statistical description of the irregularities from the scintillations they produce. In this talk, we explore some new opportunities for remote sensing ionospheric irregularities afforded by IPE. Statistical characterization of irregularities and the plasma bubbles in which they are embedded provides insight into the development of the underlying instability. In a companion paper by Rino et al., IPE is used to interpret scintillation due to simulated EPB structure. IPE can be used to reconcile multi-frequency scintillation observations and to construct high fidelity scintillation simulation tools. In space-to-ground propagation scenarios, for which an estimate of the distance to the scattering region is available a-priori, IPE enables retrieval of zonal irregularity drift. In radio occultation scenarios, the distance to the irregularities is generally unknown but IPE enables retrieval of Fresnel frequency. A geometric model for the effective scan velocity maps Fresnel frequency to Fresnel scale, yielding the distance to the irregularities. We demonstrate this approach by geolocating irregularities observed by the CORISS instrument onboard the C/NOFS satellite.

  15. [Irregular breathing during the cardiopulmonary exercise test - from mildly irregular breathing pattern to periodic breathing of oscillatory ventilation type]. (United States)

    Várnay, František; Mífková, Leona; Homolka, Pavel; Dobšák, Petr

    The fluctuating course of tidal volume (VT), breathing frequency (DF) and minute ventilation (VE) during the cardio-pulmonary exercise test using a ramp incremental protocol occurs not only in patients, but relatively frequently also in healthy individuals. It can account for a number of irregularities in the course of the curves VO2, VCO2 and in particular of those of ventilatory equivalents for O2 and CO2 (EQO2, EQCO2) as well as curves of partial pressure of end-tidal oxygen and partial pressure of end-tidal carbon dioxide (PETO2, PETCO2), which are also used, inter alia, to establish ventilatory thresholds. The presence of exercise oscillatory ventilation (EOV) reflects the severity of heart failure and it is an independent predictor of the increased morbidity, cardiac and total mortality and sudden death caused by heart failure. However there is not a generally accepted universal definition of EOV available at present, as different criteria are used. We have not found a comparison which would indicate whether and how the "strength" of the prognostic criteria for EOV - established according to different methods - differs. Therefore it is very important to specify what method, or what criteria were used in the establishment of EOV.Key words: breathing pattern - EOV - exercise oscillatory ventilation - periodic breathing.

  16. Plasma Irregularity Production in the Polar Cap F-Region Ionosphere (United States)

    Lamarche, Leslie

    Plasma in the Earth's ionosphere is highly irregular on scales ranging between a few centimeters and hundreds of kilometers. Small-scale irregularities or plasma waves can scatter radio waves resulting in a loss of signal for navigation and communication networks. The polar region is particularly susceptible to strong disturbances due to its direct connection with the Sun's magnetic field and energetic particles. In this thesis, factors that contribute to the production of decameter-scale plasma irregularities in the polar F region ionosphere are investigated. Both global and local control of irregularity production are studied, i.e. we consider global solar control through solar illumination and solar wind as well as much more local control by plasma density gradients and convection electric field. In the first experimental study, solar control of irregularity production is investigated using the Super Dual Auroral Radar Network (SuperDARN) radar at McMurdo, Antarctica. The occurrence trends for irregularities are analyzed statistically and a model is developed that describes the location of radar echoes within the radar's field-of-view. The trends are explained through variations in background plasma density with solar illumination affecting radar beam propagation. However, it is found that the irregularity occurrence during the night is higher than expected from ray tracing simulations based on a standard ionospheric density model. The high occurrence at night implies an additional source of plasma density and it is proposed that large-scale density enhancements called polar patches may be the source of this density. Additionally, occurrence maximizes around the terminator due to different competing irregularity production processes that favor a more or less sunlit ionosphere. The second study is concerned with modeling irregularity characteristics near a large-scale density gradient reversal, such as those expected near polar patches, with a particular focus on


    Directory of Open Access Journals (Sweden)

    O. M. Patlasov


    Full Text Available Purpose. Across the track superstructure (TSS there are structures where standard approach to the decision on the future of their operation is not entirely correct or acceptable. In particular, it concerns the track sections which are sufficiently quickly change their geometric parameters: the radius of curvature, angle of rotation, and the like. As an example, such portions of TSS may include crossovers where their component is within the so-called connecting part, which at a sufficiently short length, substantially changes curvature. The estimation of the position in terms of a design on the basis of the existing technique (by the difference in the adjacent arrows bending is virtually impossible. Therefore it is proposed to complement and improve the methodology for assessing the situation of the curve in plan upon difference in the adjacent versine. Methodology. The possible options for measuring horizontal curves in the plan were analyzed. The most adequate method, which does not contradict existing on the criterion of the possibility of using established standards was determined. The ease of measurement and calculation was took into account. Findings. Qualitative and quantitative verification of the proposed and existing methods showed very good agreement of the measurement results. This gives grounds to assert that this methodology can be recommended to the workers of track facilities in the assessment of horizontal irregularities in plan not only curves, but also within the connecting part of switch congresses. Originality. The existing method of valuation of the geometric position of the curves in the plan was improved. It does not create new regulations, and all results are evaluated by existing norms. Practical value. The proposed technique makes it possible, without creating a new regulatory framework, to be attached to existing one, and expanding the boundaries of its application. This method can be used not only for ordinary curves

  18. Periods, poles, and shapes of Saturn's irregular moons (United States)

    Denk, Tilmann; Mottola, Stefano


    We report rotational-lightcurve observations of irregular moons of Saturn based on disk-integrated observations with the Narrow-Angle Camera of the Cassini spacecraft. From 24 measured rotation periods, 20 are now known with an accuracy of ~2% or better. The numbers are as follows (in hours; an '*' marks the less reliable periods): Hati 5.42; Mundilfari 6.74; Loge 6.94*; Skoll 7.26; Kari 7.70; Suttungr 7.82*, Bergelmir 8.13; Phoebe 9.274; Siarnaq 10.188; Narvi 10.21; Tarvos 10.69; Skathi 11.30; Ymir 11.922; Hyrrokkin 12.76; Greip 12.79*; Ijiraq 13.03; Albiorix 13.32; Bestla 14.624; Bebhionn 16.40; Paaliaq 18.75; Kiviuq 21.96; Erriapus 28.15; Thrymr 35 or >45* Tarqeq 76.8.More recent data strengthen the notion that objects in orbits with an inclination supplemental angle i' > 27° have significantly slower spin rates than those at i' 27°, Siarnaq, stands opposed to at least eight objects with faster spins and i' 27° bin contains all nine known prograde moons and four retrograde objects.A total of 25 out of 38 known outer moons has been observed with Cassini, and there is no chance to observe the 13 missing objects until end-of-mission. However, all unobserved objects are part of the i' 27° are known, and none of them is a fast rotator, with no exception.Several objects were observed repeatedly to determine pole directions, sidereal periods, and convex shapes. A few lightcurves have been observed to show three maxima and three minima even at low phase angles, suggesting objects with a triangular equatorial cross-section. Some objects with 2 maxima/ 2 minima are probably quite elongated. One moon even shows lightcurves with 4 maxima/ 4 minima.

  19. TINITALY/01: a new Triangular Irregular Network of Italy

    Directory of Open Access Journals (Sweden)

    M. T. Pareschi


    Full Text Available A new Digital Elevation Model (DEM of the natural landforms of Italy is presented. A methodology is discussed to build a DEM over wide areas where elevation data from non-homogeneous (in density and accuracy input sources are available. The input elevation data include contour lines and spot heights derived from the Italian Regional topographic maps, satellite-based global positioning system points, ground based and radar altimetry data. Owing to the great heterogeneity of the input data density, the DEM format that better preserves the original accuracy is a Triangular Irregular Network (TIN. A Delaunay-based TIN structure is improved by using the DEST algorithm that enhances input data by evaluating inferred break-lines. Accordingly to this approach, biased distributions in slopes and elevations are absent. To prevent discontinuities at the boundary between regions characterized by data with different resolution a cubic Hermite blending weight S-shaped function is adopted. The TIN of Italy consists of 1.39×109 triangles. The average triangle area ranges from 12 to about 13000 m2 accordingly to different morphologies and different sources. About 50% of the model has a local average triangle area <500 m2. The vertical accuracy of the obtained DEM is evaluated by more than 200000 sparse control points. The overall Root Mean Square Error (RMSE is less than 3.5 m. The obtained national-scale DEM constitutes an useful support to carry out accurate geomorphological and geological investigations over large areas. The problem of choosing the best step size in deriving a grid from a TIN is then discussed and a method to quantify the loss of vertical information is presented as a function of the grid step. Some examples of DEM application are outlined. Under request, an high resolution stereo image database of the whole Italian territory (derived from the presented DEM is available to browse via internet.

  20. Coherence and predictability of extreme events in irregular waves

    Directory of Open Access Journals (Sweden)

    A. L. Latifah


    Full Text Available This paper concerns the description and the predictability of a freak event when at a certain position information in the form of a time signal is given. The prediction will use the phase information for an estimate of the position and time of the occurrence of a large wave, and to predict the measure of phase coherence at the estimated focussing position. The coherence and the spectrum will determine an estimate for the amplitude. After adjusting for second order nonlinear effects, together this then provides an estimate of the form of a possible freak wave in the time signal, which will be described by a pseudo-maximal signal. In the exceptional case of a fully coherent signal, it can be described well by a so-called maximal signal.

    We give four cases of freak waves for which we compare results of predictions with available measured (and simulated results by nonlinear AB-equation (van Groesen and Andonowati, 2007; van Groesen et al., 2010. The first case deals with dispersive focussing, for which all phases are (designed to be very coherent at position and time of focussing; this wave is nearly a maximal wave. The second case is the Draupner wave, for which the signal turns out to be recorded very close to its maximal wave height. It is less coherent but can be described in a good approximation as a pseudo-maximal wave. The last two cases are irregular waves which were measured at MARIN (Maritime Research Institute Netherlands; in a time trace of more than 1000 waves freak-like waves appeared "accidentally". Although the highest wave is less coherent than the other two cases, this maximal crest can still be approximated by a pseudo-maximal wave.

  1. Irregular Morphing for Real-Time Rendering of Large Terrain

    Directory of Open Access Journals (Sweden)

    S. Kalem


    Full Text Available The following paper proposes an alternative approach to the real-time adaptive triangulation problem. A new region-based multi-resolution approach for terrain rendering is described which improves on-the-fly the distribution of the density of triangles inside the tile after selecting appropriate Level-Of-Detail by an adaptive sampling. This proposed approach organizes the heightmap into a QuadTree of tiles that are processed independently. This technique combines the benefits of both Triangular Irregular Network approach and region-based multi-resolution approach by improving the distribution of the density of triangles inside the tile. Our technique morphs the initial regular grid of the tile to deformed grid in order to minimize approximation error. The proposed technique strives to combine large tile size and real-time processing while guaranteeing an upper bound on the screen space error. Thus, this approach adapts terrain rendering process to local surface characteristics and enables on-the-fly handling of large amount of terrain data. Morphing is based-on the multi-resolution wavelet analysis. The use of the D2WT multi-resolution analysis of the terrain height-map speeds up processing and permits to satisfy an interactive terrain rendering. Tests and experiments demonstrate that Haar B-Spline wavelet, well known for its properties of localization and its compact support, is suitable for fast and accurate redistribution. Such technique could be exploited in client-server architecture for supporting interactive high-quality remote visualization of very large terrain.

  2. Menstrual irregularity and musculoskeletal injury in female high school athletes. (United States)

    Thein-Nissenbaum, Jill M; Rauh, Mitchell J; Carr, Kathleen E; Loud, Keith J; McGuine, Timothy A


    The female athlete triad describes the interrelatedness of energy availability, menstrual function, and bone density. Although associations between triad components and musculoskeletal injury (INJ) have been reported in collegiate athletes, limited information exists about menstrual irregularity (MI) and INJ in the high school population. To determine the prevalence of and relationship between MI and INJ in high school athletes. Cross-sectional study. High schools. The sample consisted of 249 female athletes from 3 high schools who competed in 33 interscholastic, school-sponsored sport teams, dance teams, and cheerleading or pom-pon squad during the 2006-2007 school year. Each athlete remained on the roster throughout the season. Participants completed a survey regarding injury type, number of days of sport participation missed, and menstrual history in the past year. The prevalences of M I and INJ were 19.7% and 63.1 %, respectively. Athletes who reported MI sustained a higher percentage of severe injuries (missing ≥ 22 days of practice or competition) than did athletes who reported normal menses. Although the trend was not significant, athletes with MI were almost 3 times more likely to sustain an injury resulting in 7 or more days of time lost from sport (odds ratio = 2.7, 95% confidence interval = 0.8, 8.8) than those who sustained an injury resulting in 7 or fewer days of time lost. The incidences of MI and INJ in this high school population during the study period were high. Athletes who reported MI sustained a higher percentage of severe injuries than did athletes who reported normal menses. Education programs to increase knowledge and improve management of MI and its potential effects on injury in female high school athletes are warranted.

  3. K2 and Herschel/PACS photometry of irregular satellites (United States)

    Pal, Andras; Kiss, Csaba; Molnar, Laszlo; Mueller, Thomas G.; Sarneczky, Krisztian; Szabo, Robert; Kiss, Laszlo L.; Szabo, Gyula M.


    The combination of optical and far-infrared photometric measurements yields an unambiguous method for characterizing the basic physical and surface properties of minor bodies in the Solar System. In principle, an object with a certain visible brightness can either be an object with a small but bright or a large but dim surface. To resolve this issue, conducting thermal emission measurements can also be acquired since both larger and dimmer objects have higher infrared radiations. In addition, the precise modelling of thermal emission should certainly take into account the rotation period of these bodies - otherwise the presence of surface thermal inertia can result in inaccurate conclusions regarding to the physical size and albedo.Since early 2014, Kepler Space Telescope surveys fields close to the Ecliptic in a framework of quarterly campaigns of the K2 initiative. This program makes possible to continuously observe Solar System bodies during this period of 80-90 days and hence provide an uninterrupted photometric series of moving Solar System objects down to the magnitude range of R = 23.5. This instrument hence an ideal observatory now for Solar System studies. Due to the fact that the expected rotational periods of these objects are commensurable to the diurnal characteristics of ground-based observations, such uninterrupted light curves are rather valuable for the accurate determination of rotational characteristics - including the physical rotation period, the amplitude and the confirmation of the presence of double- or multiple peaked features.In this presentation we summarize our results of current K2 and legacy Herschel/PACS observations regarding to some of the irregular satellites of Uranus and Neptune, namely Caliban, Sycorax, Prospero, Setebos and Nereid. By comparing these results with similar kind of observations for trans-Neptunian objects (see Kiss et al., this DPS meeting), one can conclude how the formation and evolution of the outer Solar

  4. Ionospheric irregularities at low latitudes in the American sector

    International Nuclear Information System (INIS)

    Nakamura, Y.


    A detailed analysis of the atomic oxigem airglow emission at the wavelength of 6300 A observed at Cachoeira Paulista (22 0 41'S, 45 0 00'W) shows that intensity perturbations frequently occur and propagate from north to south and from west to east. Such irregularities originated in the ionospheric F region and occur essencially during the premidnight period. These perturbations have a high frequency of occurrence during spring and summer and are rare during winter and fall. The disturbances are correlated with range type spread F detected over Cachoeira Paulista, and have characteristics similar to equatorial ionospheric plasma bubbles (i.e., similar seazonal variation, time of occurrence, ionogram signatures, direction and speed of propagation, etc.). A numerical simulation is carried out for the generation and evolution of ionospheric bubbles based on the theory of the collisional Rayleigh-Taylor instability for the equatorial and Cachoeira Paulista regions. Also a study was made of the, evolution of the bubble as a function of the electron density profile and as a function of the amplitude of the initial density perturbation. Assuming the electron density profile perturbed by the bubble, the [OI] 6300 A intensity was calculated for various latitudes arbitrarily taken within the photometer scanning range. The bubble was assumed to be aligned with the Earth's magnetic field and extending from higher altitudes at the equatorial region down to be arbitrary height of 150 Km at which a negligible conductivity is assumed. It was also assumed that the bubble was moving upwards with the velocity of 120 m/s, which in turn was estimated from initial numerical simulation results. The airglow calculation results show that as the bubble goes up, the disturbances in the airglow intensity propagate from north to south, in accord with observed experimental results. (Author) [pt

  5. ULF Wave Associated Density Irregularities and Scintillation at the Equator (United States)

    Yizengaw, E.; Moldwin, M.; Zesta, E.


    This paper presents independent multi-instrument observations that addresses the physical mechanisms of how ULF wave associated electric fields initiate ionospheric density fluctuations and scintillation at the equator. Since the magnetic field at the equator is entirely embedded in a relatively high collision and high conductivity medium, the condition may not be possible for the geomagnetic field to fluctuate due to the damped/penetrated ULF wave. This implies the fluctuating electric field at the equator may not be produced through equatorial dynamo action due to fluctuating magnetic fields. Instead the oscillating field penetrates from high-latitudes through the TM0 (zero order transverse magnetic) mode and produce fluctuating induced magnetic field, and thus modulate the vertical drift to oscillate. We estimated the ULF associated electric field at high-latitudes and equatorial region, and demonstrated that only 15% of the fluctuating electric field from the auroral region can make to the equatorial region. We also calculated the corresponding vertical drift that oscillate with nearly identical periodicity (6-9 min) as the ULF waves in the Pc5 band. Because of its large amplitude and long periods compared to other ULF wave frequency bands, the Pc5 wave associated electric field can easily penetrate to the lower latitude region. The oscillating vertical drift at the equator has an amplitude of 2.5 - 7.0 m/s, which is 25 -50% of the typical quiet time dayside maximum value of the vertical drift at the equator, which is strong enough fluctuation to easily produce significant ionospheric density fluctuations and trigger scintillation at the equatorial region. In this paper, we present multi-instrument observations that clearly confirm the role of ULF wave penetration for the formation of density irregularities and scintillation at the equator.

  6. Studies of the Lower Ionosphere using Artificial Periodic Irregularities (United States)

    Bakhmetieva, Nataliya V.; Egerev, Mikhael N.; Tolmacheva, Ariadna V.; Vyakhirev, Valeriy D.

    Artificial periodic irregularities (API) created in the ionosphere plasma are used for the iono-sphere diagnostics. We present a new applications of API technique for experimental studies of the electron density in the lower ionosphere, atmospheric waves and sporadic E-layers. The applications are based on the new so-called two-frequency method of the API creation. The main results of the ionosphere studies carried out in 2006-2009 by the API technique using SURA heating facility are presented. API are formed in the field of a powerful standing radio wave produced by interference of the incident wave and reflected one by the ionosphere (V.V. Belikovich, E.A. Benediktov, N.V. Bakhmet'eva, A.V. Tolmacheva, Ionospheric Research by Means of Artificial Periodic Irregularities-Katlenburg-Lindau, Germany. 2002. Copernicus GmbH. ISBN 3-936586-03-9). The spatial period of the irregular structure is equal to the standing wavelength Λ or the one-half the powerful wavelength λ/2. Ionosphere diagnostics is carried out in the API relaxation (or decay) stage by their sounding of probing radio pulses. The two frequency method bases upon the API creation and the scattering of the probe waves from API at two different frequencies i.e., having different spatial periods of the quasi periodic struc-ture. In the E -region of the ionosphere API are formed as a result of the diffusion redistribution of the ionosphere plasma in the field of the powerful wave. Relaxation of the periodic structure is specified by the ambipolar diffusion process. The API relaxation time is τ = (K 2 Da )-1 where K = 2π/Λ and Da is the ambipolar diffusion rate. It means that API having different spatial scales destroys with different time scales τ . The API spatial scale depends on the refractive in-dex n that is determined by the electron density N. It is shown the ratio of API relaxation times θ at two frequencies f1 and f2 , measured at the same heights, is connected with the frequencies ratio and the

  7. Plasma Irregularities on the Leading and Trailing Edges of Polar Cap Patches (United States)

    Lamarche, L. J.; Varney, R. H.; Gillies, R.; Chartier, A.; Mitchell, C. N.


    Plasma irregularities in the polar cap have often been attributed to the gradient drift instability (GDI). Traditional fluid theories of GDI predicts irregularity growth only on the trailing edge of polar patches, where the plasma density gradient is parallel to the plasma drift velocity, however many observations show irregularities also form on the leading edge of patches. We consider decameter-scale irregularities detected by polar-latitude SuperDARN (Super Dual Auroral Radar Network) radars with any relationship between the background density gradients and drift velocity. Global electron density from the Multi-Instrument Data Analysis System (MIDAS), a GPS tomography routine, is used to provide context for where irregularities are observed relative to polar patches and finer-scale background density gradients are found from 3D imaging from both the North and Canada faces of the Resolute Bay Incoherent Scatter Radars (RISR-N and RISR-C) jointly. Shear-based instabilities are considered as mechanisms by which plasma irregularities could form on the leading edge of patches. Theoretical predictions of instability growth from both GDI and shear instabilities are compared with irregularity observations for the October 13, 2016 storm.

  8. Structural, biochemical, and computational characterization of the glycoside hydrolase family 7 cellobiohydrolase of the tree-killing fungus Heterobasidion irregulare. (United States)

    Momeni, Majid Haddad; Payne, Christina M; Hansson, Henrik; Mikkelsen, Nils Egil; Svedberg, Jesper; Engström, Åke; Sandgren, Mats; Beckham, Gregg T; Ståhlberg, Jerry


    Root rot fungi of the Heterobasidion annosum complex are the most damaging pathogens in temperate forests, and the recently sequenced Heterobasidion irregulare genome revealed over 280 carbohydrate-active enzymes. Here, H. irregulare was grown on biomass, and the most abundant protein in the culture filtrate was identified as the only family 7 glycoside hydrolase in the genome, which consists of a single catalytic domain, lacking a linker and carbohydrate-binding module. The enzyme, HirCel7A, was characterized biochemically to determine the optimal conditions for activity. HirCel7A was crystallized and the structure, refined at 1.7 Å resolution, confirms that HirCel7A is a cellobiohydrolase rather than an endoglucanase, with a cellulose-binding tunnel that is more closed than Phanerochaete chrysosporium Cel7D and more open than Hypocrea jecorina Cel7A, suggesting intermediate enzyme properties. Molecular simulations were conducted to ascertain differences in enzyme-ligand interactions, ligand solvation, and loop flexibility between the family 7 glycoside hydrolase cellobiohydrolases from H. irregulare, H. jecorina, and P. chrysosporium. The structural comparisons and simulations suggest significant differences in enzyme-ligand interactions at the tunnel entrance in the -7 to -4 binding sites and suggest that a tyrosine residue at the tunnel entrance of HirCel7A may serve as an additional ligand-binding site. Additionally, the loops over the active site in H. jecorina Cel7A are more closed than loops in the other two enzymes, which has implications for the degree of processivity, endo-initiation, and substrate dissociation. Overall, this study highlights molecular level features important to understanding this biologically and industrially important family of glycoside hydrolases.

  9. Exploring performance and energy tradeoffs for irregular applications: A case study on the Tilera many-core architecture

    Energy Technology Data Exchange (ETDEWEB)

    Panyala, Ajay; Chavarría-Miranda, Daniel; Manzano, Joseph B.; Tumeo, Antonino; Halappanavar, Mahantesh


    High performance, parallel applications with irregular data accesses are becoming a critical workload class for modern systems. In particular, the execution of such workloads on emerging many-core systems is expected to be a significant component of applications in data mining, machine learning, scientific computing and graph analytics. However, power and energy constraints limit the capabilities of individual cores, memory hierarchy and on-chip interconnect of such systems, thus leading to architectural and software trade-os that must be understood in the context of the intended application’s behavior. Irregular applications are notoriously hard to optimize given their data-dependent access patterns, lack of structured locality and complex data structures and code patterns. We have ported two irregular applications, graph community detection using the Louvain method (Grappolo) and high-performance conjugate gradient (HPCCG), to the Tilera many-core system and have conducted a detailed study of platform-independent and platform-specific optimizations that improve their performance as well as reduce their overall energy consumption. To conduct this study, we employ an auto-tuning based approach that explores the optimization design space along three dimensions - memory layout schemes, GCC compiler flag choices and OpenMP loop scheduling options. We leverage MIT’s OpenTuner auto-tuning framework to explore and recommend energy optimal choices for different combinations of parameters. We then conduct an in-depth architectural characterization to understand the memory behavior of the selected workloads. Finally, we perform a correlation study to demonstrate the interplay between the hardware behavior and application characteristics. Using auto-tuning, we demonstrate whole-node energy savings and performance improvements of up to 49:6% and 60% relative to a baseline instantiation, and up to 31% and 45:4% relative to manually optimized variants.

  10. Target Tracking of a Linear Time Invariant System under Irregular Sampling

    Directory of Open Access Journals (Sweden)

    Jin Xue-Bo


    Full Text Available Due to event-triggered sampling in a system, or maybe with the aim of reducing data storage, tracking many applications will encounter irregular sampling time. By calculating the matrix exponential using an inverse Laplace transform, this paper transforms the irregular sampling tracking problem to the problem of tracking with time-varying parameters of a system. Using the common Kalman filter, the developed method is used to track a target for the simulated trajectory and video tracking. The results of simulation experiments have shown that it can obtain good estimation performance even at a very high irregular rate of measurement sampling time.

  11. An efficient algorithm for global periodic orbits generation near irregular-shaped asteroids (United States)

    Shang, Haibin; Wu, Xiaoyu; Ren, Yuan; Shan, Jinjun


    Periodic orbits (POs) play an important role in understanding dynamical behaviors around natural celestial bodies. In this study, an efficient algorithm was presented to generate the global POs around irregular-shaped uniformly rotating asteroids. The algorithm was performed in three steps, namely global search, local refinement, and model continuation. First, a mascon model with a low number of particles and optimized mass distribution was constructed to remodel the exterior gravitational potential of the asteroid. Using this model, a multi-start differential evolution enhanced with a deflection strategy with strong global exploration and bypassing abilities was adopted. This algorithm can be regarded as a search engine to find multiple globally optimal regions in which potential POs were located. This was followed by applying a differential correction to locally refine global search solutions and generate the accurate POs in the mascon model in which an analytical Jacobian matrix was derived to improve convergence. Finally, the concept of numerical model continuation was introduced and used to convert the POs from the mascon model into a high-fidelity polyhedron model by sequentially correcting the initial states. The efficiency of the proposed algorithm was substantiated by computing the global POs around an elongated shoe-shaped asteroid 433 Eros. Various global POs with different topological structures in the configuration space were successfully located. Specifically, the proposed algorithm was generic and could be conveniently extended to explore periodic motions in other gravitational systems.

  12. Smoking, physical activity and respiratory irregularities in patients with panic disorder. (United States)

    Fadda, Emma; Galimberti, Elisa; Cammino, Stefania; Bellodi, Laura


    In the past decades different evidences suggested a relationship between panic disorder (PD) and respiration, among which the presence of different respiratory irregularities at rest in PD patients. It has been hypothesized that PD could be characterized by a dysfunction of those areas involved in the central control of respiration. The aim of the present study was to elucidate possible differences in breath-by-breath respiratory function at rest between a sample of PD patients with agoraphobia and healthy controls (HC), with particular attention to smoking and physical activity as possible relevant factors in the understanding of respiratory dynamics in PD. Respiratory physiology was assessed in 32 PD patients and 24 HC. Respiratory rate (RR), tidal volume (VT), minute ventilation (VE), and end-tidal CO2 (pCO2) have been assessed. A significant diagnosis-by-smoking interaction was found for mean RR and VT. Mean pCO2 was significantly higher in active than in sedentary patients. Anxiety state did not account for the results. Our findings suggest an abnormal regulation of the respiratory system as a key mechanism in PD. In future studies it should be useful t o stratify data taking into account level and intensity of physical activity and smoking behaviour, as well as to consider the cardiac profile and the effect of those variables able to modulate the homeostatic brain functioning. .

  13. Proper Elements and Secular Resonances for Irregular Satellites (United States)

    Beaugé, C.; Nesvorný, D.


    We present results of an analytical study of proper elements and secular resonances for the irregular satellites of the outer planets. In the case of the Jovian system we identify three satellite families, two of them previously known (Carme and Ananke), plus a new agglomeration of four bodies that includes Pasiphae as its largest member. While the distribution of proper elements for Saturn's moons seems to be more random, a small cluster was found for the direct moons formed by Albiorix, Erriapo, and 2004 S1, slightly different from the so-called Gaulish cluster. No significant families are detected in the present study for the Uranian or Neptunian satellite systems. For each satellite system we determine the location of several secular resonances in the proper element space. Apart from the well-known resonance locks of Pasiphae, Sinope, and Siarnaq, a comparison between the resonance locations and proper elements shows that Saturn's satellite Narvi also exhibits temporary librations in the ϖ-ϖsolar resonance. However, unlike the resonant Jovian moons that are located in the same configuration, Narvi's critical argument librates alternately around values near 90° and 270°. Neither the Uranian nor Neptunian systems seem to have resonant moons. The resonant dynamics of the real satellites in the vicinity of ϖ˙-ϖ˙solar=0 is studied with a simple model for secular resonances based on the restricted three-body problem. Depending on the initial conditions, we show the existence of one or two modes of libration that can occur at different values of the critical angle, showing a good correspondence with the observed behavior of all the resonant moons. Finally, we discuss the global distribution of the real satellites with respect to the secular resonances, as compared with synthetic populations of bodies drawn solely from stability conditions. For Saturn, we find that the present satellite population appears compatible with simple random distributions. Although

  14. X-ray pulsars in nearby irregular galaxies (United States)

    Yang, Jun


    The Small Magellanic Cloud (SMC), Large Magellanic Cloud (LMC) and Irregular Galaxy IC 10 are valuable laboratories to study the physical, temporal and statistical properties of the X-ray pulsar population with multi-satellite observations, in order to probe fundamental physics. The known distance of these galaxies can help us easily categorize the luminosity of the pulsars and their age difference can be helpful for for studying the origin and evolution of compact objects. Therefore, a complete archive of 116 XMM-Newton PN, 151 Chandra (Advanced CCD Imaging Spectrometer) ACIS, and 952 RXTE PCA observations for the pulsars in the Small Magellanic Cloud (SMC) were collected and analyzed, along with 42 XMM-Newton and 30 Chandra observations for the Large Magellanic Cloud, spanning 1997-2014. From a sample of 67 SMC pulsars we generate a suite of products for each pulsar detection: spin period, flux, event list, high time-resolution light-curve, pulse-profile, periodogram, and X-ray spectrum. Combining all three satellites, I generated complete histories of the spin periods, pulse amplitudes, pulsed fractions and X-ray luminosities. Many of the pulsars show variations in pulse period due to the combination of orbital motion and accretion torques. Long-term spin-up/down trends are seen in 28/25 pulsars respectively, pointing to sustained transfer of mass and angular momentum to the neutron star on decadal timescales. The distributions of pulse detection and flux as functions of spin period provide interesting findings: mapping boundaries of accretion-driven X-ray luminosity, and showing that fast pulsars (P<10 s) are rarely detected, which yet are more prone to giant outbursts. In parallel we compare the observed pulse profiles to our general relativity (GR) model of X-ray emission in order to constrain the physical parameters of the pulsars.In addition, we conduct a search for optical counterparts to X-ray sources in the local dwarf galaxy IC 10 to form a comparison

  15. The dynamics of rings around small, irregular bodies (United States)

    Sicardy, Bruno


    Stellar occultations revealed the presence of two dense rings around the Centaur object (10199) Chariklo (Braga-Ribas et al., Nature 508, 72, 2014). This is the first ring system discovered around an object that is not a giant planet, suggesting that rings may exist around numerous bodies in the solar system. Chariklo's rings roughly reside at the outer limit of the Roche zone of the body. Moreover, the main ring has sharp edges, which call for the presence of putative shepherd satellites. Those characteristics give an image of Chariklo's rings that are rather similar, in terms of dynamics, to those surrounding the gaseous planets.An important difference exists, however, between giant planets and small bodies: the formers are highly axisymmetric, while the latters can support mass anomalies (eg surface topographic features) or non-spherical shapes (eg an ellipsoidal figure of equilibrium) that involve masses, relative to the body itself, as large as 10-4-10-3.We investigate the effect of non-axisymmetric terms in the potential of the body upon a collisional debris disk that initially surrounds a small irregular body. We show that the corotation points being maxima of energy, dissipative collisions remove the particles from the corotation zone over short time scales (< 106 years). Moreover, the Lindblad resonances inside the corotation radius create torques that drive the particles onto the surface of the central body. Conversely, the outer Lindblad resonances push the disk material beyond the outer 3/2 and 2/1 Lindblad resonances.Taking as an example Chariklo's ring system, for which recent data have been obtained from stellar occultations, we show that the Lindblad resonant torques actuate over short time scales (< 106 years). This general picture offers a natural explanation of the presence of dense rings at the outer limit of Chariklo's Roche zone, and their absence closer to the body.The work leading to this results has received funding from the European

  16. Ionospheric Storm Effects and Equatorial Plasma Irregularities During the 17-18 March 2015 Event (United States)

    Zhou, Yun-Liang; Luhr, Hermann; Xiong, Chao; Pfaff, Robert F.


    .This comprehensive view of ionospheric storm effects and plasma irregularities adds to our understanding of conditions that lead to ionospheric instabilities.

  17. Understanding Carbohydrates (United States)

    ... Size: A A A Listen En Español Understanding Carbohydrates How much and what type of carbohydrate foods ... glucose levels in your target range. Explore: Understanding Carbohydrates Glycemic Index and Diabetes Learn about the glycemic ...

  18. The encoding of temporally irregular and regular visual patterns in the human brain.

    Directory of Open Access Journals (Sweden)

    Semir Zeki


    Full Text Available In the work reported here, we set out to study the neural systems that detect predictable temporal patterns and departures from them. We used functional magnetic resonance imaging (fMRI to locate activity in the brains of subjects when they viewed temporally regular and irregular patterns produced by letters, numbers, colors and luminance. Activity induced by irregular sequences was located within dorsolateral prefrontal cortex, including an area that was responsive to irregular patterns regardless of the type of visual stimuli producing them. Conversely, temporally regular arrangements resulted in activity in the right frontal lobe (medial frontal gyrus, in the left orbito-frontal cortex and in the left pallidum. The results show that there is an abstractive system in the brain for detecting temporal irregularity, regardless of the source producing it.

  19. A Numerical Method for Modeling the Effects of Irregular Shape on Interconnect Resistance (United States)

    Chen, Bao-Jun; Tang, Zhen-An; Ju, Yan-Jie


    When clock frequencies exceed gigahertz, the skin depth in analog and digital circuits greatly decreases. The irregular shape of the cross section of the interconnect plays an increasingly important role in interconnect parasitic extraction. However, existing methods only focus on the rough surface of the interconnect, while ignoring other irregular shapes, such as the trapezoidal cross section. In this work, a new simulation method is proposed for irregular interconnects, which is applicable to arbitrary irregular shapes and to a wide range of frequencies. The method involves generating a mesh information file firstly and then extracting the frequency-dependent resistance based on a numerical solution of scalar wave modeling by using the method of moments. The singularity extraction method is used to calculate the self-inductors. The data from experiments verify the accuracy of our proposed method.

  20. Women with minor menstrual irregularities have increased risk of preeclampsia and low birthweight in spontaneous pregnancies

    DEFF Research Database (Denmark)

    Bonnesen, Barbara; Oddgeirsdóttir, Hanna L; Naver, Klara Vinsand


    INTRODUCTION: Very few studies describe the obstetric and neonatal outcome of spontaneous pregnancies in women with irregular menstrual cycles. However, menstrual cycle irregularities are common and may be associated with increased risk, and women who develop pregnancy complications more frequently...... recollect irregular menstrual cycles before the time of conception in case-control studies. MATERIAL AND METHODS: This retrospective cohort study compares obstetric and neonatal outcomes in spontaneous singleton pregnancies in 3440 primiparous Danish women stratified according to menstrual cycle regularity....... All pregnancies delivered after 22 weeks of gestation and had a nuchal translucency examination at Copenhagen University Hospital Hvidovre between 1 January 2009 and 31 December 2010. Menstrual cycle irregularity was defined as more than 7 days' deviation between self-reported and ultrasound...

  1. Irregular Enemies and the Essence of Strategy: Can the American Way of War Adapt?

    National Research Council Canada - National Science Library

    Gray, Colin S


    .... Those elements are strategy, irregular enemies, and the American way of war. Carl von Clausewitz offered his theory of war in terms of a "remarkable trinity composed of primordial violence, hatred, and enmity...

  2. On Impulsive Boundary Value Problems of Fractional Differential Equations with Irregular Boundary Conditions

    Directory of Open Access Journals (Sweden)

    Guotao Wang


    Full Text Available We study nonlinear impulsive differential equations of fractional order with irregular boundary conditions. Some existence and uniqueness results are obtained by applying standard fixed-point theorems. For illustration of the results, some examples are discussed.

  3. Irregular singularities in Liouville theory and Argyres-Douglas type gauge theories, I

    International Nuclear Information System (INIS)

    Gaiotto, D.; Teschner, J.


    Motivated by problems arising in the study of N=2 supersymmetric gauge theories we introduce and study irregular singularities in two-dimensional conformal field theory, here Liouville theory. Irregular singularities are associated to representations of the Virasoro algebra in which a subset of the annihilation part of the algebra act diagonally. In this paper we define natural bases for the space of conformal blocks in the presence of irregular singularities, describe how to calculate their series expansions, and how such conformal blocks can be constructed by some delicate limiting procedure from ordinary conformal blocks. This leads us to a proposal for the structure functions appearing in the decomposition of physical correlation functions with irregular singularities into conformal blocks. Taken together, we get a precise prediction for the partition functions of some Argyres-Douglas type theories on S 4 . (orig.)

  4. Experimental Verification of Optimized Multiscroll Chaotic Oscillators Based on Irregular Saturated Functions

    Directory of Open Access Journals (Sweden)

    J. M. Muñoz-Pacheco


    Full Text Available Multiscroll chaotic attractors generated by irregular saturated nonlinear functions with optimized positive Lyapunov exponent are designed and implemented. The saturated nonlinear functions are designed in an irregular way by modifying their parameters such as slopes, delays between slopes, and breakpoints. Then, the positive Lyapunov exponent is optimized using the differential evolution algorithm to obtain chaotic attractors with 2 to 5 scrolls. We observed that the resulting chaotic attractors present more complex dynamics when different patterns of irregular saturated nonlinear functions are considered. After that, the optimized chaotic oscillators are physically implemented with an analog discrete circuit to validate the use of proposed irregular saturated functions. Experimental results are consistent with MATLAB™ and SPICE circuit simulator. Finally, the synchronization between optimized and nonoptimized chaotic oscillators is demonstrated.

  5. Irregular singularities in Liouville theory and Argyres-Douglas type gauge theories, I

    Energy Technology Data Exchange (ETDEWEB)

    Gaiotto, D. [Institute for Advanced Study (IAS), Princeton, NJ (United States); Teschner, J. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)


    Motivated by problems arising in the study of N=2 supersymmetric gauge theories we introduce and study irregular singularities in two-dimensional conformal field theory, here Liouville theory. Irregular singularities are associated to representations of the Virasoro algebra in which a subset of the annihilation part of the algebra act diagonally. In this paper we define natural bases for the space of conformal blocks in the presence of irregular singularities, describe how to calculate their series expansions, and how such conformal blocks can be constructed by some delicate limiting procedure from ordinary conformal blocks. This leads us to a proposal for the structure functions appearing in the decomposition of physical correlation functions with irregular singularities into conformal blocks. Taken together, we get a precise prediction for the partition functions of some Argyres-Douglas type theories on S{sup 4}. (orig.)

  6. Understanding Optimal Decision-Making in Wargaming (United States)


    environment that includes a combination of regular warfare, irregular warfare, terrorist activity and criminality.” This is a descriptive account of what...under instrument flight rules ( IFR ) (Bellenkes et al., 1997; Katoh, 1997). Of note, eye-tracking technology also has been applied to investigate...potential to gain additional understanding of factors affecting the quality of military decision-making exists through these technologies. The potential

  7. MEG masked priming evidence for form-based decomposition of irregular verbs

    Directory of Open Access Journals (Sweden)

    Joseph eFruchter


    Full Text Available To what extent does morphological structure play a role in early processing of visually presented English past tense verbs? Previous masked priming studies have demonstrated effects of obligatory form-based decomposition for genuinely affixed words (teacher-TEACH and pseudo-affixed words (corner-CORN, but not for orthographic controls (brothel-BROTH. Additionally, MEG single word reading studies have demonstrated that the transition probability from stem to affix (in genuinely affixed words modulates an early evoked response known as the M170; parallel findings have been shown for the transition probability from stem to pseudo-affix (in pseudo-affixed words. Here, utilizing the M170 as a neural index of visual form-based morphological decomposition, we ask whether the M170 demonstrates masked morphological priming effects for irregular past tense verbs (following a previous study which obtained behavioral masked priming effects for irregulars. Dual mechanism theories of the English past tense predict a rule-based decomposition for regulars but not for irregulars, while certain single mechanism theories predict rule-based decomposition even for irregulars. MEG data was recorded for 16 subjects performing a visual masked priming lexical decision task. Using a functional region of interest (fROI defined on the basis of repetition priming and regular morphological priming effects within the left fusiform and inferior temporal regions, we found that activity in this fROI was modulated by the masked priming manipulation for irregular verbs, during the time window of the M170. We also found effects of the scores generated by the learning model of Albright & Hayes (2003 on the degree of priming for irregular verbs. The results favor a single mechanism account of the English past tense, in which even irregulars are decomposed into stems and affixes prior to lexical access, as opposed to a dual mechanism model, in which irregulars are recognized as whole

  8. Association between sleep duration and menstrual cycle irregularity in Korean female adolescents. (United States)

    Nam, Ga Eun; Han, Kyungdo; Lee, Gyungjoo


    The association between sleep and the menstrual cycle in the adolescent population has been scarcely studied. This study aimed to investigate the association between sleep duration and menstrual cycle irregularity among female adolescents using nationwide representative data from the South Korean population. This population-based, cross-sectional study used the data collected from Korea National Health and Nutrition Examination Survey 2010-2012, and the data from 801 female adolescents were analyzed. Hierarchical multivariable logistic regression analysis was performed to assess the risk of menstrual cycle irregularity in relation to sleep duration. Subjects with menstrual cycle irregularity accounted for 15% (N = 120). The mean sleep duration in subjects with menstrual cycle irregularity was significantly shorter than that in those without (p = 0.003). Menstrual cycle irregularity prevalence tended to decrease as sleep duration increased (p for trend = 0.004), which was significantly different based on sleep duration and presence of depressive mood (p = 0.011). Sleep duration ≤5 h per day was significantly associated with increased risk of menstrual cycle irregularity compared with that in the subjects whose sleep duration is ≥8 h per day even after adjusting for confounding variables. The odds ratios of menstrual cycle irregularity tended to increase for shorter sleep duration in all adjusted models. This study found a significant inverse association between sleep duration and menstrual cycle irregularity among Korean female adolescents. Increasing sleep duration is required to improve the reproductive health of female adolescents. Copyright © 2017 Elsevier B.V. All rights reserved.

  9. Improvement of particle-based volume rendering for visualizing irregular volume data sets


    Sakamoto, Naohisa; Kawamura, Takuma; Koyamada, Koji; Nozaki, Kazunori


    We present a technique for previewing large-scale irregular volume datasets using an improved particle-based volume rendering (PBVR) technique. Volume rendering of irregular grid volume data is considerably more complicated than that of regular grid data, since the sampling and compositing processes, which must be done in visibility order, are not straightforward. In our original PBVR, rendering involves generating and projecting sub-pixel-size, opaque, and emissive particles without visibili...

  10. Irregular Warfare as a National Military Strategy Approach for Small States (United States)


    of these “pods”: the question of homogeneity or heterogeneity. There 216 Oliker, Russia´s Chechen Wars...Ronfeldt regarding the degree of homogeneity of the teams should also be evaluated. In some cases, there might be a higher degree of specialization in...prerequisites. A. IRREGULAR WARFARE – A DIRTY WAR? Based on the last decades of conflicts, the tactics used in irregular warfare have left a bad taste in the



    Naama, Mbarek


    Naama, Mbarek. Sub-Saharan Irregular Migrants in Morocco and the Exceptional Regularisation Programme in 2014. Diak South Helsinki Finland. Spring 2017. 43 Pages. Language: English. Diaconia University of Applied Sciences, Degree Programme in Social Services, Option in Community Development, Bachelor of Social Services (UAS). After decades of ignoring irregular migration and refusing to acknowledge that Morocco is no longer just a transit but also a host country for increasing complex mig...

  12. Formation of dwarf ellipticals and dwarf irregular galaxies by interaction of giant galaxies under environmental influence


    Chattopadhyay, Tanuka; Debsarma, Suma; Karmakar, Pradip; Davoust, Emmanuel


    A model is proposed for the formation of gas-rich dwarf irregular galaxies and gas-poor, rotating dwarf elliptical galaxies following the interaction between two giant galaxies as a function of space density. The formation of dwarf galaxies is considered to depend on a random variable, the tidal index theta, an environmental parameter defined by Karachentsev et al. (2004), such that for theta less than zero, the formation of dwarf irregular galaxy is assured whereas for theta greater than zer...

  13. MEG masked priming evidence for form-based decomposition of irregular verbs. (United States)

    Fruchter, Joseph; Stockall, Linnaea; Marantz, Alec


    To what extent does morphological structure play a role in early processing of visually presented English past tense verbs? Previous masked priming studies have demonstrated effects of obligatory form-based decomposition for genuinely affixed words (teacher-TEACH) and pseudo-affixed words (corner-CORN), but not for orthographic controls (brothel-BROTH). Additionally, MEG single word reading studies have demonstrated that the transition probability from stem to affix (in genuinely affixed words) modulates an early evoked response known as the M170; parallel findings have been shown for the transition probability from stem to pseudo-affix (in pseudo-affixed words). Here, utilizing the M170 as a neural index of visual form-based morphological decomposition, we ask whether the M170 demonstrates masked morphological priming effects for irregular past tense verbs (following a previous study which obtained behavioral masked priming effects for irregulars). Dual mechanism theories of the English past tense predict a rule-based decomposition for regulars but not for irregulars, while certain single mechanism theories predict rule-based decomposition even for irregulars. MEG data was recorded for 16 subjects performing a visual masked priming lexical decision task. Using a functional region of interest (fROI) defined on the basis of repetition priming and regular morphological priming effects within the left fusiform and inferior temporal regions, we found that activity in this fROI was modulated by the masked priming manipulation for irregular verbs, during the time window of the M170. We also found effects of the scores generated by the learning model of Albright and Hayes (2003) on the degree of priming for irregular verbs. The results favor a single mechanism account of the English past tense, in which even irregulars are decomposed into stems and affixes prior to lexical access, as opposed to a dual mechanism model, in which irregulars are recognized as whole forms.

  14. Stochastic analysis model for vehicle-track coupled systems subject to earthquakes and track random irregularities (United States)

    Xu, Lei; Zhai, Wanming


    This paper devotes to develop a computational model for stochastic analysis and reliability assessment of vehicle-track systems subject to earthquakes and track random irregularities. In this model, the earthquake is expressed as non-stationary random process simulated by spectral representation and random function, and the track random irregularities with ergodic properties on amplitudes, wavelengths and probabilities are characterized by a track irregularity probabilistic model, and then the number theoretical method (NTM) is applied to effectively select representative samples of earthquakes and track random irregularities. Furthermore, a vehicle-track coupled model is presented to obtain the dynamic responses of vehicle-track systems due to the earthquakes and track random irregularities at time-domain, and the probability density evolution method (PDEM) is introduced to describe the evolutionary process of probability from excitation input to response output by assuming the vehicle-track system as a probabilistic conservative system, which lays the foundation on reliability assessment of vehicle-track systems. The effectiveness of the proposed model is validated by comparing to the results of Monte-Carlo method from statistical viewpoint. As an illustrative example, the random vibrations of a high-speed railway vehicle running on the track slabs excited by lateral seismic waves and track random irregularities are analyzed, from which some significant conclusions can be drawn, e.g., track irregularities will additionally promote the dynamic influence of earthquakes especially on maximum values and dispersion degree of responses; the characteristic frequencies or frequency ranges respectively governed by earthquakes and track random irregularities are greatly different, moreover, the lateral seismic waves will dominate or even change the characteristic frequencies of system responses of some lateral dynamic indices at low frequency.

  15. Effect of Irregularity in Shape and Boundary of a Macro-Texture Region in Titanium (Postprint) (United States)


    AFRL-RX-WP-JA-2016-0328 EFFECT OF IRREGULARITY IN SHAPE AND BOUNDARY OF A MACRO-TEXTURE REGION IN TITANIUM (POSTPRINT) James L...2 October 2014 – 15 September 2015 4. TITLE AND SUBTITLE EFFECT OF IRREGULARITY IN SHAPE AND BOUNDARY OF A MACRO-TEXTURE REGION IN TITANIUM ...aerospace grade titanium alloy material are measured to be about the same level as corner trapped shear wave signals. In addition to the abnormally high

  16. An Efficient Heuristic Approach for Irregular Cutting Stock Problem in Ship Building Industry


    Yan-xin Xu


    This paper presents an efficient approach for solving a real two-dimensional irregular cutting stock problem in ship building industry. Cutting stock problem is a common cutting and packing problem that arises in a variety of industrial applications. A modification of selection heuristic Exact Fit is applied in our research. In the case referring to irregular shapes, a placement heuristics is more important to construct a complete solution. A placement heuristic relating to bottom-left-fill i...

  17. A Generalized FDM for solving the Poisson's Equation on 3D Irregular Domains

    Directory of Open Access Journals (Sweden)

    J. Izadian


    Full Text Available In this paper a new method for solving the Poisson's equation with Dirichlet conditions on irregular domains is presented. For this purpose a generalized finite differences method is applied for numerical differentiation on irregular meshes. Three examples on cylindrical and spherical domains are considered. The numerical results are compared with analytical solution. These results show the performance and efficiency of the proposed method.

  18. Welcome to the Naval Postgraduate School Center on Terrorism and Irregular Warfare, Webpage


    Center on Terrorism and Irregular Warfare


    Includes an image of the main page on this date and compressed file containing additional web pages. Established in 1998, The Center on Terrorism and Irregular Warfare produces timely, innovative, interdisciplinary analysis relevant to policy and operations. In studying terrorism and irregular warfare, the Center focuses the research capabilities of its staff and the Naval Postgraduate School on an area of critical importance to the national security of the United States.

  19. Strategic Usefulness of Conventional Force/Special Operations Force Interdependence in Irregular Warfare (United States)


    War : Afghanistan and the Vietnam Template,” Military Review 89, no. 6 (November – December 2009): 7. 99 Ibid., 7. 100 Ty Connett and Bob Cassidy...Refighting the Last War : Afghanistan and the Vietnam Template.” Military Review 89, no. 6 (November – December 2009): 2 – 14. Joint Chiefs of Staff...thesis suggests that SOF may gain the greatest strategic utility in irregular wars when operating independently against irregular threats. 14

  20. Irregular sleep habits of parents are associated with increased sleep problems and daytime sleepiness of children. (United States)

    Komada, Yoko; Adachi, Naomi; Matsuura, Noriko; Mizuno, Koh; Hirose, Kazuhiro; Aritomi, Ryoji; Shirakawa, Shuichiro


    Longitudinal studies in Japan indicate that nocturnal sleep onset has become later and sleep duration has been progressively shortened. This study aimed to investigate the relationship between sleep patterns and sleep problems among children, and to determine the association between parents and their children's sleep habits. Questionnaires about sleep problems and life habits were administered to families living in Tokyo metropolitan areas of Japan. We analyzed the data of pre-school-age (1-5 years old; n = 319, including 175 girls) and elementary school-age children (6-11 years; n = 217, including 116 girls) as well as their parents (402 mothers: 37.0 +/- 4.9 years, 402 fathers: 39.0 +/- 5.9 years). Subjects were categorized as morning (evening) type when they answered their lifestyle habit as "definitely or moderately morning (evening) type". Sleep was categorized into regular, irregular, and intermediate from the sleeping-waking regularity scores. The frequency of daytime dozing is significantly high in children with evening-irregular sleep. Moreover, mothers of children (aged 1-5 and 6-11 years) with evening-irregular sleep have significantly more irregular sleep habits than those of children with morning-regular sleep. Likewise, fathers of children (aged 1-5 years) with evening-irregular sleep have significantly more irregular sleep habits. Thus, irregular late bedtime of parents is associated with sleep problems, daytime sleepiness, and irregular dietary habits of children. Mothers' sleep habits have a stronger influence on their children's sleep than fathers'. Our study indicates the importance of promoting sleep hygiene that encourages healthy sleep for all family members.

  1. Dynamics of landslides on comets of irregular shape (United States)

    Czechowski, Leszek


    Landslides were observed on a few comet's nuclei, e.g. [1], [2]. The mechanism of their origin is not obvious because of very low gravity. According to [2] fluidization and multiphase transport of cometary material could be an explanation. We investigate here motion of the mass on a comet of irregular shape. The mechanism responsible for the low friction is not considered here. In fact, mass motion often occurs without contact with the surface. The motion could be triggered by meteoroids impacts or by the tidal forces. Comets nuclei are believed to be built of soft materials like snow and dust. The landing of Philae on the comet 67P/Czuriumow-Gierasimienko indicates a different situation. According to [1]: "thermal probe did not fully penetrate the near-surface layers, suggesting a local resistance of the ground to penetration of >4 megapascals, equivalent to >2 megapascal uniaxial compressive strength". Here we assume that elastic properties of comet's nuclei could be similar to elastic properties of dry snow, namely Young modulus is assumed to be 1 - 100 MPa, see [3] and [4]. We consider nucleus of the shape of 67P/Churyumov-Gerasimenko with density 470 kg/m3. The impact or tidal forces result in changing of rotation of the comet. In general, the vector of angular velocity will be a subject to nutation that results in changing of centrifugal force, and consequently could be a factor triggering landslides. Note that nucleus' shape does not resemble the shape of surface of constant value of gravitational potential (i.e. 'geoid'). Our numerical models indicate the parts of the nucleus where landslides start and other parts where landslides stop. Of course, the regolith from the first type of regions would be removed to the regions of the second class. The motion of the mass is often complicated because of complicated distribution of the gravity and complicated shape of the nucleus. Acknowledgement: The research is partly supported by Polish National Science Centre

  2. Occurrence of Equatorial F Region Irregularities: Evidence for Tropospheric Seeding (United States)

    McClure, J. P.; Singh, S.; Bamgboye, D. K.; Johnson, F. S.; Kil, Hyosub


    We present a new gap-free version of the seasonal and longitudinal 0 (s/l) variations of P(sub EFI), the equatorial F region irregularity (EFI) occurrence probability, based on data from the AE-E spacecraft. The agreement of this and three earlier partial P(sub EFI) patterns verifies all four. We reinterpret another earlier gap-ridden pattern, that of D(bar)(sub RSF), a topside ionogram index of average darkening by range spread F. We compare it with P(sub EFI) and, using ionosonde radio science considerations, we conclude that D(bar)(sub RSF) = P(sub EFI) times a factor depending on the average number of topside plasma bubbles visible to the ionosonde. The s/l variations of D(baar)(sub RSF) thus imply s/l variations in the average spacing of bubbles, whose seeds have an occurrence probability pattern P(sub seed). For discussion we assume P(sub EFI) = P(sub inst)P(sub seed) is the pattern of F region instability. The P(sub EFI) pattern, which is by definition independent of seed and/or bubble spacing, is far too complex to be explained by the dominant paradigm, that of changes in P(sub inst) by simple changes in the F region altitude and/or north-south asymmetry. We examine evidence behind this dominance, and find it unconvincing. Both the asymmetry and sunset-node/altitude hypotheses of 1984 and 1985, respectively, seem to be partly based on misunderstood data, and their features appear displaced in time and space from those of our repeatable P(sub EFI) pattern. In contrast, if P(sub seed) variations influence the P(sub EFI) pattern and depend on thermospheric gravity waves from tropospheric convection near the dip equator, then the seasonal maxima (minima) Of P(sub EFI) could be explained, since they all occur above relatively warm (cold) surface features, where convection is maximal (minimal). Also, the hypothesis of the dominance of the P(sub seed) term could explain an unusual December/January P(sub EFI) maximum in the deep, wide, normal Pacific minimum in the

  3. Properties of the Irregular Satellite System around Uranus Inferred from K2 , Herschel , and Spitzer Observations

    Energy Technology Data Exchange (ETDEWEB)

    Farkas-Takács, A.; Kiss, Cs.; Pál, A.; Molnár, L.; Szabó, Gy. M.; Hanyecz, O.; Sárneczky, K.; Szabó, R.; Marton, G.; Szakáts, R.; Kiss, L. L. [Konkoly Observatory, Research Centre for Astronomy and Earth Sciences, Hungarian Academy of Sciences, Konkoly Thege Miklós út 15-17, H-1121 Budapest (Hungary); Mommert, M. [Department of Physics and Astronomy, Northern Arizona University, P.O. Box 6010, Flagstaff, AZ 86011 (United States); Müller, T., E-mail: [Max-Plank-Institut für extraterrestrsiche Pyhsik, Garching (Germany)


    In this paper, we present visible-range light curves of the irregular Uranian satellites Sycorax, Caliban, Prospero, Ferdinand, and Setebos taken with the Kepler Space Telescope over the course of the K2 mission. Thermal emission measurements obtained with the Herschel /PACS and Spitzer /MIPS instruments of Sycorax and Caliban were also analyzed and used to determine size, albedo, and surface characteristics of these bodies. We compare these properties with the rotational and surface characteristics of irregular satellites in other giant planet systems and also with those of main belt and Trojan asteroids and trans-Neptunian objects. Our results indicate that the Uranian irregular satellite system likely went through a more intense collisional evolution than the irregular satellites of Jupiter and Saturn. Surface characteristics of Uranian irregular satellites seem to resemble the Centaurs and trans-Neptunian objects more than irregular satellites around other giant planets, suggesting the existence of a compositional discontinuity in the young solar system inside the orbit of Uranus.

  4. Characterizing neural activities evoked by manual acupuncture through spiking irregularity measures

    International Nuclear Information System (INIS)

    Xue Ming; Wang Jiang; Deng Bin; Wei Xi-Le; Yu Hai-Tao; Chen Ying-Yuan


    The neural system characterizes information in external stimulations by different spiking patterns. In order to examine how neural spiking patterns are related to acupuncture manipulations, experiments are designed in such a way that different types of manual acupuncture (MA) manipulations are taken at the ‘Zusanli’ point of experimental rats, and the induced electrical signals in the spinal dorsal root ganglion are detected and recorded. The interspike interval (ISI) statistical histogram is fitted by the gamma distribution, which has two parameters: one is the time-dependent firing rate and the other is a shape parameter characterizing the spiking irregularities. The shape parameter is the measure of spiking irregularities and can be used to identify the type of MA manipulations. The coefficient of variation is mostly used to measure the spike time irregularity, but it overestimates the irregularity in the case of pronounced firing rate changes. However, experiments show that each acupuncture manipulation will lead to changes in the firing rate. So we combine four relatively rate-independent measures to study the irregularity of spike trains evoked by different types of MA manipulations. Results suggest that the MA manipulations possess unique spiking statistics and characteristics and can be distinguished according to the spiking irregularity measures. These studies have offered new insights into the coding processes and information transfer of acupuncture. (interdisciplinary physics and related areas of science and technology)

  5. Do Irregularly Shaped School Attendance Zones Contribute to Racial Segregation or Integration? (United States)

    Saporito, Salvatore; Van Riper, David


    This research investigates if and how much the shapes of school attendance zones contribute to racial segregation in schools. We find that the typical school attendance zone is relatively compact and resembles a square-like shape. Compact zones typically draw children from local residential areas, and since local areas are often racially homogeneous, this suggests that high levels of racial segregation in the largest school districts are largely structured by existing residential segregation. Still, this study finds that the United States contains some attendance zones with highly irregular shapes-some of which are as irregular as the most irregular Congressional District. Although relatively rare, attendance zones that are highly irregular in shape almost always contain racially diverse student populations. This racial diversity contributes to racial integration within school districts. These findings contradict recent theoretical and empirical scholarship arguing that irregularly shaped zones contribute to racial segregation in schools. Our findings suggest that most racial segregation in school attendance zones is driven by large-scale segregation across residential areas rather than a widespread practice among school districts to exacerbate racial segregation by delineating irregularly shaped attendance zones.

  6. New prospective 4D-CT for mitigating the effects of irregular respiratory motion (United States)

    Pan, Tinsu; Martin, Rachael M.; Luo, Dershan


    Artifact caused by irregular respiration is a major source of error in 4D-CT imaging. We propose a new prospective 4D-CT to mitigate this source of error without new hardware, software or off-line data-processing on the GE CT scanner. We utilize the cine CT scan in the design of the new prospective 4D-CT. The cine CT scan at each position can be stopped by the operator when an irregular respiration occurs, and resumed when the respiration becomes regular. This process can be repeated at one or multiple scan positions. After the scan, a retrospective reconstruction is initiated on the CT console to reconstruct only the images corresponding to the regular respiratory cycles. The end result is a 4D-CT free of irregular respiration. To prove feasibility, we conducted a phantom and six patient studies. The artifacts associated with the irregular respiratory cycles could be removed from both the phantom and patient studies. A new prospective 4D-CT scanning and processing technique to mitigate the impact of irregular respiration in 4D-CT has been demonstrated. This technique can save radiation dose because the repeat scans are only at the scan positions where an irregular respiration occurs. Current practice is to repeat the scans at all positions. There is no cost to apply this technique because it is applicable on the GE CT scanner without new hardware, software or off-line data-processing.

  7. Understanding classification

    NARCIS (Netherlands)

    Subianto, M.


    In practical data analysis, the understandability of models plays an important role in their acceptance. In the data mining literature, however, understandability plays is hardly ever mentioned. If it is mentioned, it is interpreted as meaning that the models have to be simple. In this thesis we

  8. Irregular antibodies in no hemolytic autoimmune diseases are able to induce erythrophagocytosis. (United States)

    López-Díaz, Paola Ester; Ruiz-Olivera, María Del Rocío; Hernández-Osorio, Luis Alberto; Vargas-Arzola, Jaime; Valle-Jiménez, Xareni; Aguilar-Ruiz, Sergio Roberto; Torres-Aguilar, Honorio


    Irregular antibodies are produced by alloimmunization because of pregnancies or blood transfusions. They are called "irregular" due to target erythrocyte antigens from "rare blood systems," those different from the ABO system. Irregular antibodies have been widely investigated in immunohematology since their presence in blood donors may lead to difficulties in blood typing and in blood cross-matching, or to induce hemolytic transfusion reactions. Nevertheless, their incidence and participation in the physiopathology of autoimmune diseases have not been thoroughly studied. In this work, we analyzed the presence and pro-hemolytic capabilities of irregular antibodies in patients with different autoimmune diseases lacking signs of hemolytic anemia, in comparison with healthy multiparous women. Five of 141 autoimmune patients (3.5 %) and two of 77 multiparous women (2.6 %) were positive. Although frequency was relatively low and similar in both populations, the targeted antigens were Kell (k, Kp b , Js b ) and Luth (Lu b ) in multiparous women, and the same plus Duffy (Fy a ), Kidd (Jk a ) and MNS (M, s) in autoimmune patients. Irregular antibodies from autoimmune patients did not induce complement-mediated hemolysis (intravascular), but they were able to induce macrophages-mediated phagocytosis (extravascular hemolysis) in vitro. It is the first approach exploring the presence of irregular antibodies associated with the loss of immune tolerance and demonstrating their hemolytic potential in autoimmune patients without hemolytic manifestations. The presence of irregular antibodies targeted to Duffy (Fya), Kidd (Jka) and MNS (M, s) antigens only in autoimmune patients suggests a loss of immune tolerance to these erythrocyte antigens.

  9. The association between mental health problems and menstrual cycle irregularity among adolescent Korean girls. (United States)

    Yu, Mi; Han, Kyungdo; Nam, Ga Eun


    Menstrual cycle irregularity is common among adolescents and can induce mental health problems such as stress, depression, and suicidal ideation. We examined the association between mental health problems and menstrual cycle irregularity among adolescent Korean girls. This population-based cross-sectional study was on 808 female adolescents (12-18 years of age) participating in the 2010-2012 Korean National Health and Nutrition Examination Survey. Psychological stress, depressive mood, suicidal ideations, suicide attempts, and psychological counseling were assessed through questionnaires and surveys, and hierarchical multivariable logistic regression analysis was performed. The risk of menstrual cycle irregularity tended to increase, as the number of mental health problems increased (P for trend=0.016). High stress levels, depressive mood, and psychological counseling were associated with increased risks of menstrual cycle irregularity (odd ratio [95% confidence interval]=1.88 [1.1-3.21], 2.01 [1.01-4.03], and 2.92 [1.16-7.34], respectively) even after adjusting for age, body mass index, alcohol consumption, smoking status, physical activity, hemoglobin level, monthly household income, weight loss attempts, age at menarche, and sleep duration. Suicidal ideation was not significantly associated with menstrual cycle irregularity. Menstrual irregularity was evaluated based solely on subjects' self-reports, which are subject to their subjective perceptions and appraisal. Cross-sectional design and retrospective data could not draw causal relationship. Positive associations were observed between mental health problems and menstrual cycle irregularity among adolescent Korean girls. More attention should be paid towards mental health, to improve menstrual cycle regularity and help prevent related chronic diseases later in life. Copyright © 2016 Elsevier B.V. All rights reserved.

  10. Optimizing Chinese character displays improves recognition and reading performance of simulated irregular phosphene maps. (United States)

    Lu, Yanyu; Kan, Han; Liu, Jie; Wang, Jing; Tao, Chen; Chen, Yao; Ren, Qiushi; Hu, Jie; Chai, Xinyu


    A visual prosthesis may elicit an irregular phosphene map relative to a regular electrode array. This study used simulated irregular phosphene maps as a way of optimizing the display methods of Chinese characters (CCs) to improve recognition and reading performance. TWENTY SUBJECTS WITH NORMAL OR CORRECTED SIGHT PARTICIPATED IN TWO EXPERIMENTS (9 FEMALES, 11 MALES, 2030 YEARS OF AGE). EXPERIMENT 1: two character display methods were proposed: selecting phosphenes covered by character strokes on a simulated phosphene array (projection method) and finding the phosphene closest to the expected location in some range of an irregular phosphene array as a substitute (nearest neighbor search [NNS] method). The recognition accuracy of CCs was investigated using six levels for the coverage ratio of stroke and phosphene area and for search range, respectively, for two methods, for several irregularity levels. Experiment 2: reading accuracy (RA) and reading efficiency (RE) were measured using the regular array correspondence and NNS methods. EXPERIMENT 1: projection and NNS methods were significantly affected by coverage ratio or search range. NNS significantly improved CC recognition accuracy to the highest at 81.3 ± 2.7% and 59.1 ± 5.2%, respectively, for different irregularity levels, compared with the projection method. Experiment 2: RA and RE significantly decreased as the distortion level increased; NNS significantly improved RA (from approximately 40% to >80%) and RE (from approximately 13 char/min to >40 char/min) when reading more irregular paragraphs. The performance of CC recognition and paragraph reading when using an irregular phosphene array can be improved through optimizing the display method.

  11. Irregular breathing during 4DCT scanning of lung cancer patients: is the midventilation approach robust? (United States)

    Aznar, Marianne C; Persson, Gitte F; Kofoed, Inger M; Nygaard, Ditte E; Korreman, Stine S


    With 4DCT the risk of introducing positional systematic errors in lung cancer radiotherapy can be minimised. A common approach is to plan on the phase bin of the 4DCT best representing the tumour's time-weighted mean position also called the midventilation scan. However breathing irregularities can introduce uncertainties and potentially misrepresent both the tumour trajectory and the determination of the midventilation phase. In this study we evaluated the robustness of the midventilation approach in the presence of irregular breathing patterns. A LEGO Mindstorms(®) phantom with compact balls simulating lung tumours was constructed. The breathing curves loaded in the phantom were either acquired from a human volunteer or constructed with various magnitudes (ranging from 12 to 29 mm) as well as various irregularities of motion pattern. Repeated 4DCT scans were performed while tumour trajectories were recorded with two motion tracking systems. The time-weighted mean tumour position is accurately represented in 4DCT scans, even for irregular breathing patterns: the position presentation in the midventilation scan was always within in one standard deviation of the global position presentation (3 mm and 2 mm for regular and irregular breathing patterns, respectively). The displacement representation tended to be underestimated in 4DCT scans. The midventilation approach is robust even in the presence of breathing irregularity. The representation of the tumour trajectory in 4DCT scans is affected by breathing irregularity and the extent of tumour motion can be underestimated, which will affect the calculation of patient-individualised margins based on the 4DCT scan. Copyright © 2013 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

  12. Experimental study on the assessment of safety allowance taken in shield irregularity design method

    International Nuclear Information System (INIS)

    Miura, Toshimasa; Hirao, Yoshihiro; Odano, Naoteru; Ishida, Toshihisa; Sato, Osamu; Okuno, Koichi


    Investigation and assessment are carried out for approximate design calculation methods of radiation streaming in shield irregularities. Investigation items are definition of source and streaming radiation components, calculation methods of streaming radiation, streaming formulas for each irregularity, problems in application of streaming formulas, simple calculation codes and albedo data. As a result, it is clarified that streaming calculation formulas are not enough to cover various irregularities and their accuracy or application limit is not sufficiently clear. Accurate treatment is not made in the formulas with respect to the radiation behavior for slant incidence, bend part, offset and so on that results in too much safety factors in the design calculation and distrust of the streaming calculation. To overcome the state and improve the accuracy of the design calculation for shield irregularities, a simple method is developed to calculate radiation streaming through irregularities in an ordinary concrete shield. It includes neutron and gamma-ray calculations and can be applied to the problems of practical slant incidence. The method is essentially one of summing the streaming dose rates from the different neutron and gamma components which are functions of energy and angle of incident radiation, dimensions of irregularities, etc. Dose rates in irregularities are calculated by the Monte Carlo code MCNP. Radiation sources are plane mono-dimensional fission neutrons, intermediate neutrons, thermal neutrons and 1.25-MeV gamma rays. Incident angles of radiation are changed between 0 and 60deg. For bend ducts or slits, an isotropic plane source is placed inside the inlet opening to reduce computation time. Calculated results are arranged into the form of a database. Reliability of the Monte Carlo calculations are assessed by comparison with experiments using a 60 Co source or a 252 Cf source and calculations by an one-dimensional discrete ordinates code ANISN

  13. Irregular water supply, household usage and dengue: a bio-social study in the Brazilian Northeast Abastecimento irregular de água, seu uso domiciliar e dengue: uma pesquisa biossocial no Nordeste do Brasil

    Directory of Open Access Journals (Sweden)

    Andrea Caprara


    Full Text Available Despite increased vector control efforts, dengue fever remains endemic in Fortaleza, Northeast Brazil, where sporadic epidemic outbreaks have occurred since 1986. Multiple factors affect vector ecology such as social policy, migration, urbanization, city water supply, garbage disposal and housing conditions, as well as community level understanding of the disease and related practices. This descriptive study used a multi-disciplinary approach that bridged anthropology and entomology. A multiple case study design was adopted to include research in six study areas, defined as blocks. The water supply is irregular in households from both under-privileged and privileged areas, however, clear differences exist. In the more privileged blocks, several homes are not connected to the public water system, but have a well and pump system and therefore irregularity of supply does not affect them. In households from under-privileged blocks, where the water supply is irregular, the frequent use of water containers such as water tanks, cisterns, barrels and pots, creates environmental conditions with a greater number of breeding areas. In under-privileged homes, there are more possible breeding areas and environmental conditions that may improve the chances of Aedes aegypti survival.Apesar do crescimento de esforços no controle, desde 1986, a dengue, em Fortaleza, Nordeste do Brasil, continua endêmica com esporádicos surtos epidêmicos. Diversos fatores influenciam a ecologia do vetor, como as políticas sociais, a migração, a urbanização, o abastecimento urbano de água, a coleta de resíduos sólidos, as condições das casas, assim como as interpretações e práticas da comunidade. Este estudo descritivo utiliza uma abordagem multidisciplinar conjugando a antropologia e a entomologia. Foi adotado um desenho de estudo de caso múltiplo em seis quarteirões da cidade. O abastecimento de água é irregular seja nas casas pobres, seja naquelas

  14. Embodied understanding. (United States)

    Johnson, Mark


    Western culture has inherited a view of understanding as an intellectual cognitive operation of grasping of concepts and their relations. However, cognitive science research has shown that this received intellectualist conception is substantially out of touch with how humans actually make and experience meaning. The view emerging from the mind sciences recognizes that understanding is profoundly embodied, insofar as our conceptualization and reasoning recruit sensory, motor, and affective patterns and processes to structure our understanding of, and engagement with, our world. A psychologically realistic account of understanding must begin with the patterns of ongoing interaction between an organism and its physical and cultural environments and must include both our emotional responses to changes in our body and environment, and also the actions by which we continuously transform our experience. Consequently, embodied understanding is not merely a conceptual/propositional activity of thought, but rather constitutes our most basic way of being in, and engaging with, our surroundings in a deep visceral manner.

  15. Drop sizes and particle coverage in emulsions stabilised solely by silica nanoparticles of irregular shape. (United States)

    Binks, Bernard P; Fletcher, Paul D I; Holt, Benjamin L; Parker, James; Beaussoubre, Pascal; Wong, Kenneth


    We have investigated emulsions stabilised solely by partially-hydrophobised fumed silica particles which consist of a mixture of primary particles and irregularly-shaped fused aggregates and larger agglomerates. The particle wettability is controlled by varying the extent of hydrophobisation of their surfaces. This, in turn, controls the contact angle between the oil-water interface and the particle surface (θ(ow)) which affects the particle adsorption energy and the type of emulsion formed (oil-in-water, o/w or water-in-oil, w/o). Progressive particle hydrophobisation causes transitional phase inversion of the emulsions from o/w to w/o which occurs when θ(ow) = 90° and the energy of particle adsorption to the oil-water interface is maximally favourable. The key problem addressed here is to understand why the emulsion drop size passes through a minimum at the point of emulsion phase inversion. In principle, this effect could be the result of particle desorption, changes in the extent of close-packing of the adsorbed particle film (at constant particle orientation), particle re-orientation or a combination of these processes. Using measurements of emulsion drop size and the extent of particle desorption, we have derived adsorbed particle surface concentrations as a function of the energy of desorption of the particles from the oil-water interface for a range of particle concentrations and different oil-water systems. The main conclusion is that the minimum in emulsion drop size through phase inversion is mainly caused by re-orientation of the particles from a high surface area orientation when the energy of desorption is high to a low surface area orientation when the energy of desorption is low. Some particle desorption occurs but this is a secondary effect.

  16. Displacement and stress fields around rock fractures opened by irregular overpressure variations

    Directory of Open Access Journals (Sweden)

    Shigekazu eKusumoto


    Full Text Available Many rock fractures are entirely driven open by fluids such as ground water, geothermal water, gas, oil, and magma. These are a subset of extension fractures (mode I cracks; e.g., dikes, mineral veins and joints referred to as hydrofractures. Field measurements show that many hydrofractures have great variations in aperture. However, most analytical solutions for fracture displacement and stress fields assume the loading to be either constant or with a linear variation. While these solutions have been widely used, it is clear that a fracture hosted by heterogeneous and anisotropic rock is normally subject to loading that is neither constant nor with a linear variation. Here we present new general solutions for the displacement and stress fields around hydrofractures, modelled as two-dimensional elastic cracks, opened by irregular overpressure variations given by the Fourier cosine series. Each solution has two terms. The first term gives the displacement and stress fields due to the average overpressure acting inside the crack; it is given by the initial term of the Fourier coefficients expressing the overpressure variation. The second term gives the displacement and stress fields caused by the overpressure variation; it is given by general terms of the Fourier coefficients and solved through numerical integration. Our numerical examples show that the crack aperture variation closely reflects the overpressure variation. Also, that the general displacement and stress fields close to the crack follow the overpressure variation but tend to be more uniform far from the crack. The present solutions can be used to estimate the displacement and stress fields around any fluid-driven crack, that is, any hydrofracture, as well as its aperture, provided the variation in overpressure can be described by Fourier series. The solutions add to our understanding of local stresses, displacements, and fluid transport associated with hydrofractures in the crust.

  17. Soil-structure interaction analysis of jack-up platforms subjected to monochrome and irregular waves (United States)

    Korzani, Maziar Gholami; Aghakouchak, Ali Akbar


    As jack-up platforms have recently been used in deeper and harsher waters, there has been an increasing demand to understand their behaviour more accurately to develop more sophisticated analysis techniques. One of the areas of significant development has been the modelling of spudcan performance, where the load-displacement behaviour of the foundation is required to be included in any numerical model of the structure. In this study, beam on nonlinear winkler foundation (BNWF) modeling—which is based on using nonlinear springs and dampers instead of a continuum soil media—is employed for this purpose. A regular monochrome design wave and an irregular wave representing a design sea state are applied to the platform as lateral loading. By using the BNWF model and assuming a granular soil under spudcans, properties such as soil nonlinear behaviour near the structure, contact phenomena at the interface of soil and spudcan (such as uplifting and rocking), and geometrical nonlinear behaviour of the structure are studied. Results of this study show that inelastic behaviour of the soil causes an increase in the lateral displacement at the hull elevation and permanent unequal settlement in soil below the spudcans, which are increased by decreasing the friction angle of the sandy soil. In fact, spudcans and the underlying soil cause a relative fixity at the platform support, which changes the dynamic response of the structure compared with the case where the structure is assumed to have a fixed support or pinned support. For simulating this behaviour without explicit modelling of soil-structure interaction (SSI), moment-rotation curves at the end of platform legs, which are dependent on foundation dimensions and soil characteristics, are obtained. These curves can be used in a simplified model of the platform for considering the relative fixity at the soil-foundation interface.

  18. [Characteristics of blood type irregular antibodies in Han population of Chinese Sichuan area]. (United States)

    Li, Cui-Ying; Li, Yun-Ming; Huang, Fei; Xiao, Jie; Xu, Hong


    To analyze the distribution of irregular antibody of red blood cells in Han population of Chinese Sichuan area, so as to provide valuable information for the safety of transfusion and decrease of immune hemolytic transfusion reaction. Blood samples from June 2006 to May 2013 were tested for irregular antibody screening and identification, calculating the composition rate, group characteristics and the positive detection rate of irregular antibody. A total of 36287 blood samples were tested, out of them 571 samples were the irregular antibody positive, the positive rate was 1.574%(571/36 287), specific alloantibodies were found in 312 samples, the positive rate was 0.860%(312/36287). And autoantibody was found in 259 samples, the positive rate was 0.714%(259/36 287). The specific alloantibodies ratio in Rh system was the highest, reaching to 73.72%(230/312) with the positive rate of 0.634%;36 cases in Lewis system, account for 11.54%(36/312) with the positive rate of 0.099%; 34 cases in MNS system account for 10.89%(34/312) with the positive rate of 0.094%; direct coomb test showed positive result in 284 samples, the rate was 0.78%. The detected rate of positive irregular antibody in female is obviously higher than that in male patients (Pirregular antibody screening and identification are very important in blood transfusion, especially for female and people with transfusion or pregnant history.

  19. [Advance of clinical study on immune thrombocytopenia caused by irregular antibodies]. (United States)

    Zhu, Lin-Lin; Zhang, Chen-Guang


    The platelet antibodies mainly include platelet-specific and related antibodies, which belong to irregular antibodies. They are produced by autoimmune, drug-induced or isoimmunization (such as pregnancy, blood transfusion and so on), the irregular IgG and/or IgM antibodies produce and lead to platelet transfusion refractoriness (PTR), post-transfusion purpura (PTP) and isoimmune neonatal thrombocytopenic purpura (INTP), idiopathic thrombocytopenic purpura and so on. It is very necessary to screen and identify the irregular antibodies before blood transfusion or parturition. Except some serological detections should be done first, flow cytometry and molecular biological techniques such as PCR and PCR-SSP are applied to detect the difficult-matching patients' genotypes and fetal genotypes in order to further predict fetal INTP and to provide the right blood for difficult-matching patients, therefore, some measures must be taken early for prevention and treatment of immune thrombocytopenic purpura. In this review, the production, typing and laboratory tests of irregular antibodies, as well as the pathogenesis and clinical symptoms of diseases caused by irregular antibodies, and the current progress are summarized.

  20. Haemolytic disease of the newborn due to maternal irregular antibodies in the Chinese population in Taiwan. (United States)

    Wu, K H; Chu, S L; Chang, J G; Shih, M C; Peng, C T


    From 1991 to 2000, amongst 23,886 full-term healthy Chinese babies delivered at our hospital, 2615 babies developed neonatal hyperbilirubinaemia. After excluding other causes of hyperbilirubinaemia and identifying the irregular antibodies, 15 cases of haemolytic disease of the newborn (HDN) due to maternal irregular antibodies were diagnosed; three cases were born in our hospital and 12 cases were referred. Amongst these 15 babies, six cases had HDN due to anti-E, three cases due to anti-E + c, three cases due to anti-D, one case due to anti-c and two cases due to 'Mi' antibodies reacting with MiIII phenotype cells (anti-Hil and anti-Mur). Although there were four cases of hydrops fetalis, only one of the patients expired. The prevalence of HDN caused by maternal irregular antibodies has been estimated to be 0.01%. Therefore, routine prenatal screening for irregular antibodies was not rational in the Chinese population in Taiwan. Anti-E and anti-E + c were the important irregular antibodies resulting in HDN. Although few cases of HDN due to anti-'Mi' have been reported, Anti-'Mi' is significant in regions with a high prevalence of the MiIII phenotype.

  1. Dispositional resilience as a moderator of the relationship between chronic stress and irregular menstrual cycle. (United States)

    Palm-Fischbacher, Simona; Ehlert, Ulrike


    Menstrual-cycle irregularity may have an important influence on the subsequent development of chronic diseases. Several risk factors for irregular menstrual cycles have been detected, including stress. Our aim was to extend research on the link between chronic stress and menstrual-cycle irregularity and to assess potential protective factors, such as dispositional resilience, which we hypothesize to be associated with the maintenance or promotion of a healthy menstrual cycle. For this cross-sectional study, data on 696 healthy women aged 20-40 years were obtained. The women completed measures of chronic stress, dispositional resilience and menstrual-cycle irregularity. Furthermore, potential confounds were assessed. Of the participants, 383 (55%) reported no current use of hormonal contraceptives; 313 (45%) reported current use hormonal contraception and were included as a control group. The results suggest that in women not using hormonal contraception, chronic stress (OR = 1.05, 95%CI = 1.02-1.08, p = 0.001) and dispositional resilience (OR = 0.43, 95%CI = 0.31-0.59, p menstrual cycle regularity. In addition, women with greater dispositional resilience have reduced risk for irregular menstrual cycles in the face of low to moderate chronic stress; however, this association is changed at the highest level of chronic stress. These findings suggest that dispositional resilience may be a protective psychological trait that modulates reproductive functioning.

  2. Scleral Lenses in the Management of Corneal Irregularity and Ocular Surface Disease. (United States)

    Shorter, Ellen; Harthan, Jennifer; Nau, Cherie B; Nau, Amy; Barr, Joseph T; Hodge, David O; Schornack, Muriel M


    To describe current practice patterns regarding the use of scleral lens therapy in the management of corneal irregularity and ocular surface disease among eye care providers who fit scleral lenses. The Scleral Lenses in Current Ophthalmic Practice: an Evaluation (SCOPE) study group conducted an electronic survey of eye care providers from January 15 to March 31, 2015. Respondents ranked management options for corneal irregularity in the order in which they would generally consider their use. Respondents also ranked options for the management of ocular surface disease in the order in which they would use each of the treatments. Results for each option were analyzed as percentage first-place ranking; percentage first-, second-, or third-place ranking; and mean rank score. Survey responses were obtained from 723 providers who had fit 5 or more scleral lenses. Of these respondents, 629 ranked options for management of corneal irregularity and 612 ranked options for management of ocular surface disease. Corneal rigid gas-permeable lenses were the first option for management of corneal irregularity for 44% of respondents, and scleral lenses were the first option for 34% of respondents. Lubricant drops were the first therapeutic recommendation for ocular surface disease for 84% of respondents, and scleral lenses were ranked first by 6% of respondents. Scleral lenses rank second only to corneal rigid gas-permeable lenses for management of corneal irregularity. Scleral lenses are generally considered after other medical intervention and before surgery for the management of ocular surface disease.

  3. The nature and source of irregular discharges to stormwater entering Sydney estuary, Australia

    International Nuclear Information System (INIS)

    Beck, H.J.; Birch, G.F.


    Irregular discharges of polluted stormwater into drainage systems during base flow (no rainfall) result in acute ecological impacts within fluvial and estuarine environments. In this study, metal and TSS concentrations were significantly more variable during business hours of weekdays (i.e. high-business activity) than weekends/public holidays (i.e. low-business activity) within three highly-urbanised catchments of Sydney estuary (Australia), as determined by analysing multivariate dispersion (PERMDISP). Concentrations of TSS and all metals analysed (Al, Ca, Cu, Fe, Mg, Pb and Zn) were also significantly greater during high- than low-business periods within at least one of the three catchments. In no case were concentrations significantly higher during low- than high-business periods. This pattern of contamination supports the hypothesis that commercial and industrial sources are major contributors of irregular discharges of contamination to Sydney estuary. Irregular discharges and consequential ecological impacts may be effectively reduced in this environment by focussing management efforts on these activities. - Highlights: • Irregular discharges of pollution have acute impacts on aquatic ecosystems. • These discharges were thought to be made during low activity periods, such as night. • Pollution was more concentrated and erratic during high- than low-business periods. • Timing of pollution suggests commercial and industrial activities are major sources. • Discharges effectively reduced by managing commercial and industrial activities. - Previously unreported irregular, illegal discharges of polluted stormwater released to estuaries result in acute ecological impacts and are potentially related to commercial/industrial activities

  4. Factors associated with irregular breakfast consumption among high school students in a Japanese community. (United States)

    Oba, Shino; Oogushi, Kazuhiro; Ogata, Hiromitsu; Nakai, Hiromitsu


    This study evaluated the associations between the characteristics of high school students and irregular breakfast consumption and explored the association with knowledge regarding diet and dietary education in a community in Japan. A cross-sectional survey using a self-administered questionnaire was conducted in 2007 among all the high school students in the second grade in Imari, Saga. Data for 318 male and 292 female students were analyzed. Irregular breakfast consumption was defined as consuming breakfast three times or less in a week. The associations between the characteristics of students and irregular breakfast consumption were assessed using logistic regression with adjustments for sex and school. Among male students, a strong association between the consumption of juice or pop and irregular breakfast consumption was observed (OR comparing ">=2 servings" vs "rarely"=8.97, 95% CI=2.99-26.9). The associations with wake times and bed times were strong among male students, and the association with regular bowel movements was strong among female students. Students who had knowledge of regional agricultural and livestock products were more likely to consume breakfast regularly, and this association was significant among female students (OR=2.89, 95% CI=1.23-6.82). Significant associations were also observed with the consumption of snacks, and traditional greeting before meals. Several characteristics, including specific knowledge, were associated with the irregular consumption of breakfast. The results are of interest to policy makers, nutrition specialists, and educators working to enhance regular breakfast consumption among students.

  5. Application of the pothole DAF method to vehicles traversing periodic roadway irregularities (United States)

    Pesterev, A. V.; Bergman, L. A.; Tan, C. A.; Yang, B.


    This paper is a sequel to the work discussed in Pesterev et al. (Journal of Sound and Vibration, in press). In that paper, it was suggested that the technique to determine the effect of a local road surface irregularity on the dynamics of a vehicle modelled as a linear multi-degree-of-freedom system relies on the so-called pothole dynamic amplification factor (DAF), which is a complex-valued function specific to the irregularity shape. This paper discusses the companion problem of how to determine the DAF function for an irregularity represented as a superposition of simpler ones. Another purpose of this paper is to demonstrate the application of the pothole DAF functions technique to finding a priori estimates of the effect of irregularities with a repeated structure. Specifically, we solve the problem of finding the conditions under which the dynamic effect of two identical potholes located one after another is greater than that due to the single pothole. We also find the estimate for the number of periods of a periodic irregularity that are sufficient in order to consider the oscillator response as steady state. The discussions are illustrated by numerical examples.

  6. Morning Cortisol Levels and Perceived Stress in Irregular Shift Workers Compared with Regular Daytime Workers

    Directory of Open Access Journals (Sweden)

    Harri Lindholm


    Full Text Available The 24/7 work environment and irregular shifts may markedly enhance the psychological pressure of media work. Changes in the hypothalamic-pituitary-adrenal axis reflect adaptation to stress. We analysed the correlation between subjective stress, sleep, salivary cortisol, and melatonin hormones among Finnish media workers with regular daytime work (RDW and with irregular shift work (ISW while controlling confounders. From 874 employees with regular daytime work or with irregular shift work, 70 employees from both groups were randomly selected. The final number of employees with a complete salivary cortisol profile was 66 in the RDW group and 65 in the ISW group. Five saliva samples were gathered from each subject before and during a working day. The salivary cortisol level of the sample taken 60 minutes after awakening (T1 was compared to the salivary cortisol level taken immediately after awakening (T0, T1/T0 ratio. The ratio was higher in the ISW group than in RDW group. Irregular shift work (P<0.001, severe stress (P<0.05, and less sleep (P<0.05 were independently associated with an augmented cortisol response after awakening. A stressful work environment and irregular shift work enhance cortisol excretion after waking. In the long run, this may become detrimental to health.

  7. Understanding semantics

    DEFF Research Database (Denmark)

    Thrane, Torben


    Understanding natural language is a cognitive, information-driven process. Discussing some of the consequences of this fact, the paper offers a novel look at the semantic effect of lexical nouns and the identification of reference types....

  8. Understanding Alzheimer's (United States)

    ... Navigation Bar Home Current Issue Past Issues Understanding Alzheimer's Past Issues / Fall 2007 Table of Contents For ... and brain scans. No treatment so far stops Alzheimer's. However, for some in the disease's early and ...

  9. Impacts of Electrode Coating Irregularities on Polymer Electrolyte Membrane Fuel Cell Lifetime Using Quasi In-Situ Infrared Thermography and Accelerated Stress Testing

    Energy Technology Data Exchange (ETDEWEB)

    Bender, Guido [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Phillips, Adam [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Ulsh, Michael J [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Neyerlin, Kenneth C [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Porter, Jason [Colorado School of Mines


    In-line quality control diagnostics for roll-to-roll (R2R) manufacturing techniques will play a key role in the future commercialization of the polymer electrolyte membrane fuel cell (PEMFC) used in automotive applications. These diagnostics monitor the fabrication of the membrane electrode assembly (MEA), which detect and flag any non-uniformity that may potentially harm PEMFC performance and/or lifetime. This will require quantitative thresholds and a clear distinction between harmful defects and harmless coating irregularities. Thus, novel fuel cell hardware with quasi in-situ infrared (IR) thermography capabilities is utilized to understand how bare spots in the cathode electrode impact MEA lifetime. An accelerated stress test (AST) simulates chemical and mechanical degradation modes seen in vehicular operation. The actual open circuit voltage and rate of change of this voltage are used as in-situ indicators for MEA failure, enabling capture of the progression of failure point development. Bare spot coating irregularities located at the center of the electrode were found to have no impact on MEA lifetime when compared to a pristine MEA. However, MEA lifetime was found to be considerably shortened when these same irregularities are located at the cathode inlet and, especially, the anode inlet regions of the fuel cell.

  10. Understanding homelessness


    Somerville, Peter


    This paper reviews the literature on understanding homelessness. It criticizes approaches that ignore, distort or diminish the humanity of homeless people, or else, add little to our understanding of that humanity. In particular, it rejects what it calls “epidemiological” approaches, which deny the possibility of agency for homeless people, insofar as those approaches view the situation of those people largely as a “social fact”, to be explained in terms of causal variables or “risk factors” ...

  11. Prices and costs of irregularity in renewable resources in the liberalized electricity markets

    International Nuclear Information System (INIS)

    Menanteau, Ph.; Finon, D.


    The problems raised by incorporating irregular production are of a technical nature (risk of non-availability during peak demand, the requirements for additional reserves) but the electricity markets methods of operation impose economic penalties, which greatly exceed these additional technical costs. In this document, the authors examine the nature of the technical problems posed by irregularity of production and the additional costs resulting from this, and then analyse the origins of the economic penalties that the operation of liberalized electricity markets impose, taking in particular the example of the British market, the New Energy Trading Arrangement (NETA). It would appear that the markets' operating rules may conflict, in certain cases, with the targets for promoting electricity generation from renewable resources. Two types of solutions can therefore be envisaged: a set of rules to limit the impact on irregular production or collective handling of the adjustment to production from renewable resources as already exists in the Nordic electricity markets. (authors)

  12. Application of Wuhan Ionospheric Oblique Backscattering Sounding System (WIOBSS) for the investigation of midlatitude ionospheric irregularities (United States)

    Wang, Jin; Zhou, Xiaoming; Qiao, Lei; Gong, Wanlin


    An upgrade of Wuhan Ionospheric Backscattering Sounding System (WIOBSS) was developed in 2015. Based on the Universal Serial Bus (USB), and a high performance FPGA, the newly designed WIOBSS has a completely digital structure, which makes it portable and flexible. Two identical WIOBSSs, which were situated at Mile (24.31°N, 103.39°E) and Puer (22.74°N, 101.05°E) respectively, were used to investigate the ionospheric irregularities. The comparisons of group distance, Doppler shift and width between Mile-Puer and Puer-Mile VHF ionospheric propagation paths indicate that the reciprocity of the irregularities is satisfied at midlatitude region. The WIOBSS is robust in the detection of ionospheric irregularities.

  13. Vulnerability, irregular migrants' health-related rights and the European Court of Human Rights. (United States)

    Da Lomba, Sylvie


    The protection of irregular migrants' health-related rights brings to the fore the tensions that exist between human rights, citizenship and the sovereign state, and exposes the protection gaps in the international human rights regime. With this in mind, I consider the merits of a vulnerability analysis in international human rights law (IHRL). I posit that, detached from specific groups and reconceptualised as universal, vulnerability can be reclaimed as a foundation and tool of IHRL. I further contend that the deployment of a vulnerability analysis can alleviate the exclusionary dimension of IHRL and extend protections to irregular migrants. On this basis, I investigate the development of a vulnerability analysis in the case law of the European Court of Human Rights. I argue that, in contrast with the Court's vulnerable population approach, a vulnerability analysis can improve protection standards for irregular migrants in the field of health.

  14. Energy Extraction from a Slider-Crank Wave Energy under Irregular Wave Conditions: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Sang, Yuanrui; Karayaka, H. Bora; Yan, Yanjun; Zhang, James Z.; Muljadi, Eduard; Yu, Yi-Hsiang


    A slider-crank wave energy converter (WEC) is a novel energy conversion device. It converts wave energy into electricity at a relatively high efficiency, and it features a simple structure. Past analysis on this particular WEC has been done under regular sinusoidal wave conditions, and suboptimal energy could be achieved. This paper presents the analysis of the system under irregular wave conditions; a time-domain hydrodynamics model is adopted and a rule-based control methodology is introduced to better serve the irregular wave conditions. Results from the simulations show that the performance of the system under irregular wave conditions is different from that under regular sinusoidal wave conditions, but a reasonable amount of energy can still be extracted.

  15. Working irregular shift patterns is associated with functional constipation among healthy trainee nurses

    Directory of Open Access Journals (Sweden)

    Ali Ebrahim


    Full Text Available The circadian system has a role in regulating gastrointestinal physiology. Perturbation of this system is associated with gastrointestinal tract dysfunction. Shiftwork and poor sleep quality are associated with functional gastrointestinal disorders among many professional groups. This study compared bowel habits between trainee nurses with regular and irregular patterns of shiftwork. Male and female nursing students, enrolled on the first year (regular shifts; n=49 and the fourth year (irregular shifts, n=48 of a nursing degree course were surveyed. Questionnaires were used to assess functional diarrhea and constipation over a three month period. The prevalence of functional constipation among regular shift workers was lower than that found among irregular shift workers; 31.3% and 61.2%, respectively. There was no difference between the two groups in relation to the prevalence of diarrhea. This suggests an association between shiftwork and functional constipation, but not with functional diarrhea.

  16. Spiking irregularity and frequency modulate the behavioral report of single-neuron stimulation. (United States)

    Doron, Guy; von Heimendahl, Moritz; Schlattmann, Peter; Houweling, Arthur R; Brecht, Michael


    The action potential activity of single cortical neurons can evoke measurable sensory effects, but it is not known how spiking parameters and neuronal subtypes affect the evoked sensations. Here, we examined the effects of spike train irregularity, spike frequency, and spike number on the detectability of single-neuron stimulation in rat somatosensory cortex. For regular-spiking, putative excitatory neurons, detectability increased with spike train irregularity and decreasing spike frequencies but was not affected by spike number. Stimulation of single, fast-spiking, putative inhibitory neurons led to a larger sensory effect compared to regular-spiking neurons, and the effect size depended only on spike irregularity. An ideal-observer analysis suggests that, under our experimental conditions, rats were using integration windows of a few hundred milliseconds or more. Our data imply that the behaving animal is sensitive to single neurons' spikes and even to their temporal patterning. Copyright © 2014 Elsevier Inc. All rights reserved.

  17. Detection of a Solitude Senior's Irregular States Based on Learning and Recognizing of Behavioral Patterns (United States)

    Aoki, Shigeki; Onishi, Masaki; Kojima, Atsuhiro; Fukunaga, Kunio

    Recently, attention is paid to monitoring systems that watch behavior of a solitude person in home as the population of solitude seniors has increased. This paper proposes a monitoring system focused on behavioral patterns of a solitude senior. In general, the number of behavioral patterns are limited in the case of aged person in a room. It is possible for a system like a HMM to learn the frequently appeared behavioral patterns. By utilizing HMMs to deal with behavioral patterns, the system can detect irregular pattern by the degree of likelihood in the case when non-daily behavioral patterns appeared. Such a case could be an irregular state of the living life of the person. Soon after, the system reports an alarm of occurrence of the irregular state according to demand.

  18. Plasma irregularities caused by cycloid bunching of the CRRES G-2 barium release (United States)

    Bernhardt, P. A.; Huba, J. D.; Pongratz, M. B.; Simons, D. J.; Wolcott, J. H.


    The Combined Release and Radiation Effects Satellite (CRRES) spacecraft carried a number of barium thermite canisters for release into the upper atmosphere. The barium release labeled G-2 showed evidence of curved irregularities not aligned with the ambient magnetic field B. The newly discovered curved structures can be explained by a process called cycloid bunching. Cycloid bunching occurs when plasma is created by photoionization of a neutral cloud injected at high velocity perpendicular to B. If the injection velocity is much larger than the expansion speed of the cloud, the ion trail will form a cycloid that has irregularities spaced by the product of the perpendicular injection speed and the ion gyroperiod, Images of the solar-illuminated barium ions are compared with the results of a three-dimensional kinetic simulation. Cycloid bunching is shown to be responsible for the rapid generation of both curved and field-aligned irregularities in the CRRES G-2 experiment.

  19. Pressure drop across the distributor in fluidized beds with regular and irregular distributor design

    International Nuclear Information System (INIS)

    Ho, T.C.; Chen, T.K.; Hopper, J.R.


    The characteristics of the distributor pressure drop in a fluidized bed corresponding to perforated distributor plates with regular and irregular distributor design were studied. Distributor pressure drops were measured in an empty bed and beds with different fluidizing particles or bed heights. The design variables tested included the open area ratio, hole size, hole lay-out, plate thickness and design irregularity. The characteristics of distributor pressure drop corresponding to abnormal operating conditions, i.e., hole blocking and channeling, were also examined. The results indicate that the open area ratio is the most critical parameter governing the plate pressure drop for a regular distributor and that the design irregularity has a strong effect on the distributor behavior when particles are present. The study has given rise to a criterion for uniform air distribution across the distributor holes

  20. The majority of irregular menstrual cycles in adolescence are ovulatory: results of a prospective study. (United States)

    Peña, Alexia S; Doherty, Dorota A; Atkinson, Helen C; Hickey, Martha; Norman, Robert J; Hart, Roger


    While ovulation is most likely to occur in adolescent girls with regular menstrual cycles, there are limited data on the incidence of ovulation in girls with irregular menstrual cycles in early postmenarcheal years. The aim of the study was to evaluate the presence of ovulation in healthy postmenarcheal girls with irregular menstrual cycles. Prospective cohort study over 12 weeks including 40 healthy postmenarcheal girls recruited from the population-based cohort of adolescents from Western Australian Pregnancy Cohort (Raine) Study with irregular menstrual cycles defined by either menstrual cycles 35 days in duration or cycle length that varied from month to month by >4 days according to menstrual diaries. Ovulation defined by urinary pregnanediol-3α-glucuronide/creatinine measurements higher than three times above minimum value obtained from 12 samples (1 per week). Forty girls (37 Caucasians) with irregular menstrual cycles aged 15.1 (median (IQR) 14.9-15.4) years who were 2.3 (1.9-3.3) years postmenarche were assessed. Urinary pregnanediol-3α-glucuronide/creatinine values identified that 33 girls (82.5%) ovulated during the 3 months of observation and 7 girls had anovulatory cycles. Menstrual diaries collected for a median (IQR) of 159 (137.5-188.2) days showed median minimal and maximum menstrual cycle duration of 24 (11.5-29) and 38.5 (35-48) days, respectively. A large proportion of healthy adolescent girls with irregular menstrual cycles are still ovulating despite irregular and infrequent menses. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.


    Newman, Aaron J.; Ullman, Michael T.; Pancheva, Roumyana; Waligura, Diane L.; Neville, Helen J.


    Compositionality is a critical and universal characteristic of human language. It is found at numerous levels, including the combination of morphemes into words and of words into phrases and sentences. These compositional patterns can generally be characterized by rules. For example, the past tense of most English verbs (“regulars”) is formed by adding an -ed suffix. However, many complex linguistic forms have rather idiosyncratic mappings. For example, “irregular” English verbs have past tense forms that cannot be derived from their stems in a consistent manner. Whether regular and irregular forms depend on fundamentally distinct neurocognitive processes (rule-governed combination vs. lexical memorization), or whether a single processing system is sufficient to explain the phenomena, has engendered considerable investigation and debate. We recorded event-related potentials while participants read English sentences that were either correct or had violations of regular past tense inflection, irregular past tense inflection, syntactic phrase structure, or lexical semantics. Violations of regular past tense and phrase structure, but not of irregular past tense or lexical semantics, elicited left-lateralized anterior negativities (LANs). These seem to reflect neurocognitive substrates that underlie compositional processes across linguistic domains, including morphology and syntax. Regular, irregular, and phrase structure violations all elicited later positivities that were maximal over right parietal sites (P600s), and which seem to index aspects of controlled syntactic processing of both phrase structure and morphosyntax. The results suggest distinct neurocognitive substrates for processing regular and irregular past tense forms: regulars depending on compositional processing, and irregulars stored in lexical memory. PMID:17070703

  2. Validation of DEM prediction for granular avalanches on irregular terrain (United States)

    Mead, Stuart R.; Cleary, Paul W.


    Accurate numerical simulation can provide crucial information useful for a greater understanding of destructive granular mass movements such as rock avalanches, landslides, and pyroclastic flows. It enables more informed and relatively low cost investigation of significant risk factors, mitigation strategy effectiveness, and sensitivity to initial conditions, material, or soil properties. In this paper, a granular avalanche experiment from the literature is reanalyzed and used as a basis to assess the accuracy of discrete element method (DEM) predictions of avalanche flow. Discrete granular approaches such as DEM simulate the motion and collisions of individual particles and are useful for identifying and investigating the controlling processes within an avalanche. Using a superquadric shape representation, DEM simulations were found to accurately reproduce transient and static features of the avalanche. The effect of material properties on the shape of the avalanche deposit was investigated. The simulated avalanche deposits were found to be sensitive to particle shape and friction, with the particle shape causing the sensitivity to friction to vary. The importance of particle shape, coupled with effect on the sensitivity to friction, highlights the importance of quantifying and including particle shape effects in numerical modeling of granular avalanches.

  3. Understanding Maple

    CERN Document Server

    Thompson, Ian


    Maple is a powerful symbolic computation system that is widely used in universities around the world. This short introduction gives readers an insight into the rules that control how the system works, and how to understand, fix, and avoid common problems. Topics covered include algebra, calculus, linear algebra, graphics, programming, and procedures. Each chapter contains numerous illustrative examples, using mathematics that does not extend beyond first-year undergraduate material. Maple worksheets containing these examples are available for download from the author's personal website. The book is suitable for new users, but where advanced topics are central to understanding Maple they are tackled head-on. Many concepts which are absent from introductory books and manuals are described in detail. With this book, students, teachers and researchers will gain a solid understanding of Maple and how to use it to solve complex mathematical problems in a simple and efficient way.

  4. Irregular Enemies and the Essence of Strategy: Can the American Way of War Adapt? (United States)


    American way of war. Carl von Clausewitz offered his theory of war in terms of a “remarkable trinity composed of primordial violence , hatred, and...its style of warfare in order to meet the distinctive challenges posed by an irregular enemy. In both periods, new technology was harnessed to “the...oversimplified manner. Bear in mind the ambiguity about the notion of “irregular enemies.” That can mean enemies of any genus who choose to fight in an

  5. Less Efficient Neural Processing Related to Irregular Sleep and Less Sustained Attention in Toddlers (United States)

    Hoyniak, Caroline P.; Petersen, Isaac T.; McQuillan, Maureen E.; Staples, Angela D.; Bates, John E.


    The current study used event-related potentials to examine a candidate process through which sleep difficulties affect attentional processing in toddlers. Fifteen toddlers participated in an auditory Oddball Task while neurophysiological data were collected. Sleep deficits were assessed using actigraphs, and attention was examined with a sustained attention task. A P3-like component was elicited from the toddlers, and longer target P3 latencies were associated with poorer sustained attention and irregular sleep. Findings suggest that irregular sleep is associated with less efficient attentional processing as reflected by the P3 component, and that longer target P3 latencies are associated with poorer sustained attention. PMID:26151613

  6. Influence of Rhizoglomus irregulare on nutraceutical quality and regeneration of Lycium barbarum leaves under salt stress. (United States)

    Liu, Hongguang; Wang, Yajun; Chen, Hui; Tang, Ming


    Whether arbuscular mycorrhizal fungi augment the nutraceutical quality of crops under salt stress is critical as a potential agronomic practice in salinized farmland. To evaluate the effect of Rhizoglomus irregulare on the nutraceutical quality of Lycium barbarum leaves under salt stress, we analyzed growth parameters and the rutin, polysaccharide, acidic polysaccharide, and amino acids contents of 2 harvests. Inoculation of R. irregulare significantly increased the regenerated bud number (partial eta squared (PES) = 0.577, P nutraceutical quality and facilitated the sustainable production of L. barbarum leaves exposed to salt stress.

  7. Discrete transfer method with the concept of blocked-off region for irregular geometries

    Energy Technology Data Exchange (ETDEWEB)

    Talukdar, Prabal [Institute of Fluid Mechanics (LSTM), University of Erlangen-Nuremberg, Cauerstrasse 4, D-91058 Erlangen (Germany)]. E-mail:


    The discrete transfer method (DTM) is applied to irregular geometries with a concept of blocked-off region previously applied in the problems of computational fluid dynamics. This gives a new alternative to the DTM for its implementation to irregular structures. The Cartesian coordinate-based ray-tracing algorithm can be applied to the geometries with inclined or curved boundaries. Some test problems are considered and results are validated with the available results in the literature. Both radiative and non-radiative equilibrium situations are considered. The medium is assumed to be both participating and non-participating. Results are found to be accurate for all kinds of situations.

  8. A Tire Model for Off-Highway Vehicle Simulation on Short Wave Irregular Terrain

    DEFF Research Database (Denmark)

    Langer, Thomas Heegaard; Kristensen, Lars B; Mouritsen, Ole Ø.


    Manufacturers of construction machinery are challenged in several ways concerning dynamic loads. Considering off-highway dump trucks that travel through high amplitude short wave irregular terrain with considerable speed two aspects concerning dynamics are important. The first is the legal...... the tire ground interaction for big off-road tires on short wave irregular terrain. In this paper a simple tire model combining the well known slip theory and a displaced volume approach is presented. A non-gradient optimization routine is applied for parameter identification by minimizing the difference...

  9. Planar irregularities of texture and stress field in Ti detected by X-ray diffraction technique (United States)

    Tarkowski, L.; Bonarski, J.; Alexandrov, I.


    Regardless of the origin of structure irregularities of materials, the recognition of their spatial distribution in a sample or constructing elements is a great research problem. One of the most effective and non-destructive tools used for this purpose is the X-ray diffraction technique, assisted by an appropriate experimental method and data processing. The work presents the results of investigations of planar distribution of crystallographic texture and stress irregularities manifested by changes of diffraction effects registered by the X-ray technique. As an example, the introduced method is tested on a titanium rod after severe plastic deformation process.

  10. Regular-, irregular-, and pseudo-character processing in Chinese: The regularity effect in normal adult readers

    Directory of Open Access Journals (Sweden)

    Dustin Kai Yan Lau


    Full Text Available Background Unlike alphabetic languages, Chinese uses a logographic script. However, the pronunciation of many character’s phonetic radical has the same pronunciation as the character as a whole. These are considered regular characters and can be read through a lexical non-semantic route (Weekes & Chen, 1999. Pseudocharacters are another way to study this non-semantic route. A pseudocharacter is the combination of existing semantic and phonetic radicals in their legal positions resulting in a non-existing character (Ho, Chan, Chung, Lee, & Tsang, 2007. Pseudocharacters can be pronounced by direct derivation from the sound of its phonetic radical. Conversely, if the pronunciation of a character does not follow that of the phonetic radical, it is considered as irregular and can only be correctly read through the lexical-semantic route. The aim of the current investigation was to examine reading aloud in normal adults. We hypothesized that the regularity effect, previously described for alphabetical scripts and acquired dyslexic patients of Chinese (Weekes & Chen, 1999; Wu, Liu, Sun, Chromik, & Zhang, 2014, would also be present in normal adult Chinese readers. Method Participants. Thirty (50% female native Hong Kong Cantonese speakers with a mean age of 19.6 years and a mean education of 12.9 years. Stimuli. Sixty regular-, 60 irregular-, and 60 pseudo-characters (with at least 75% of name agreement in Chinese were matched by initial phoneme, number of strokes and family size. Additionally, regular- and irregular-characters were matched by frequency (low and consistency. Procedure. Each participant was asked to read aloud the stimuli presented on a laptop using the DMDX software. The order of stimuli presentation was randomized. Data analysis. ANOVAs were carried out by participants and items with RTs and errors as dependent variables and type of stimuli (regular-, irregular- and pseudo-character as repeated measures (F1 or between subject

  11. Understanding physics

    CERN Document Server

    Mansfield, Michael


    Understanding Physics - Second edition is a comprehensive, yet compact, introductory physics textbook aimed at physics undergraduates and also at engineers and other scientists taking a general physics course. Written with today's students in mind, this text covers the core material required by an introductory course in a clear and refreshing way. A second colour is used throughout to enhance learning and understanding. Each topic is introduced from first principles so that the text is suitable for students without a prior background in physics. At the same time the book is designed to enable

  12. Co-evolutionary dynamics of the bacteria Vibrio sp. CV1 and phages V1G, V1P1, and V1P2: implications for phage therapy. (United States)

    Barbosa, Camilo; Venail, Patrick; Holguin, Angela V; Vives, Martha J


    Bacterial infections are the second largest cause of mortality in shrimp hatcheries. Among them, bacteria from the genus Vibrio constitute a major threat. As the use of antibiotics may be ineffective and banned from the food sector, alternatives are required. Historically, phage therapy, which is the use of bacteriophages, is thought to be a promising option to fight against bacterial infections. However, as for antibiotics, resistance can be rapidly developed. Since the emergence of resistance is highly undesirable, a formal characterization of the dynamics of its acquisition is mandatory. Here, we explored the co-evolutionary dynamics of resistance between the bacteria Vibrio sp. CV1 and the phages V1G, V1P1, and V1P2. Single-phage treatments as well as a cocktail composed of the three phages were considered. We found that in the presence of a single phage, bacteria rapidly evolved resistance, and the phages decreased their infectivity, suggesting that monotherapy may be an inefficient treatment to fight against Vibrio infections in shrimp hatcheries. On the contrary, the use of a phage cocktail considerably delayed the evolution of resistance and sustained phage infectivity for periods in which shrimp larvae are most susceptible to bacterial infections, suggesting the simultaneous use of multiple phages as a serious strategy for the control of vibriosis. These findings are very promising in terms of their consequences to different industrial and medical scenarios where bacterial infections are present.

  13. Understanding Energy (United States)

    Menon, Deepika; Shelby, Blake; Mattingly, Christine


    "Energy" is a term often used in everyday language. Even young children associate energy with the food they eat, feeling tired after playing soccer, or when asked to turn the lights off to save light energy. However, they may not have the scientific conceptual understanding of energy at this age. Teaching energy and matter could be…

  14. Understanding translation

    DEFF Research Database (Denmark)

    Schjoldager, Anne Gram; Gottlieb, Henrik; Klitgård, Ida

    Understanding Translation is designed as a textbook for courses on the theory and practice of translation in general and of particular types of translation - such as interpreting, screen translation and literary translation. The aim of the book is to help you gain an in-depth understanding...... of the phenomenon of translation and to provide you with a conceptual framework for the analysis of various aspects of professional translation. Intended readers are students of translation and languages, but the book will also be relevant for others who are interested in the theory and practice of translation...... - translators, language teachers, translation users and literary, TV and film critics, for instance. Discussions focus on translation between Danish and English....

  15. Understanding Resilience

    Directory of Open Access Journals (Sweden)

    Gang eWu


    Full Text Available Resilience is the ability to adapt successfully in the face of stress and adversity. Stressful life events, trauma and chronic adversity can have a substantial impact on brain function and structure, and can result in the development of PTSD, depression and other psychiatric disorders. However, most individuals do not develop such illnesses after experiencing stressful life events, and are thus thought to be resilient. Resilience as successful adaptation relies on effective responses to environmental challenges and ultimate resistance to the deleterious effects of stress, therefore a greater understanding of the factors that promote such effects is of great relevance. This review focuses on recent findings regarding genetic, epigenetic, developmental, psychosocial and neurochemical factors that are considered essential contributors to the development of resilience. Neural circuits and pathways involved in mediating resilience are also discussed. The growing understanding of resilience factors will hopefully lead to the development of new pharmacological and psychological interventions for enhancing resilience and mitigating the untoward consequences.

  16. Understand electronics

    CERN Document Server

    Bishop, Owen


    Understand Electronics provides a readable introduction to the exciting world of electronics for the student or enthusiast with little previous knowledge. The subject is treated with the minimum of mathematics and the book is extensively illustrated.This is an essential guide for the newcomer to electronics, and replaces the author's best-selling Beginner's Guide to Electronics.The step-by-step approach makes this book ideal for introductory courses such as the Intermediate GNVQ.

  17. Understanding users

    DEFF Research Database (Denmark)

    Johannsen, Carl Gustav Viggo


    Segmentation of users can help libraries in the process of understanding user similarities and differences. Segmentation can also form the basis for selecting segments of target users and for developing tailored services for specific target segments. Several approaches and techniques have been...... segmentation project using computer-generated clusters. Compared to traditional marketing texts, this article also tries to identify user segments or images or metaphors by the library profession itself....

  18. Understanding unemployment


    Guillaume Rocheteau


    Modern economists have built models of the labor market, which isolate the market’s key drivers and describe the way these interact to produce particular levels of unemployment. One of the most popular models used by macroeconomists today is the search-matching model of equilibrium unemployment. We explain this model, and show how it can be applied to understand the way various policies, such as unemployment benefits, taxes, or technological changes, can affect the unemployment rate.

  19. Effect of surface stress and irregularity of the interface on the ...

    Indian Academy of Sciences (India)

    MS received 27 May 2007; revised 4 March 2009. Abstract. The object of the present paper is to investigate plane SH waves through a magneto-elastic crustal layer based over an elastic, solid semi space under the influence of surface stress on the free surface of the crustal layer and irregularity of the interface. Two types of ...

  20. Meal irregularity and cardiometabolic consequences: results from observational and intervention studies

    NARCIS (Netherlands)

    Pot, G.K.; Almoosawi, S; Stephen, AM


    Studying irregular meal patterns fits in with the latest research focusing not only on what people eat but also when they eat, also called chrono-nutrition. Chrono-nutrition involves studying the impact of nutrition on metabolism via circadian patterns, including three aspects of time:

  1. [Irregular antierythocytic antibodies outside of the ABO system in the perinatal period]. (United States)

    Baptista-González, H A; Rosenfeld-Mann, F; Pérez-Pérez, J D; Quintanar-García, E


    Included in this study are the results of the tests done with irregular anti-erythrocytic antibodies outside of the ABO system of women in reproductive stage. In 2,623 cases considered, 279 samples positive for the antibodies were found (10.6%). In 184 cases (65.9%), the antibodies were classified as "immune irregular". The most frequently found antibodies from this group were the anti-D (63.08%), followed by the anti-c (1.07%), the anti-Kell (0.72%), anti-C, anti-E and an anti-Rh system (0.36% for each one). In 52 cases (18.6%) there were irregular "natural" antibodies, predominantly the anti-Lewis (9.68%), followed by anti-P (5.02%), the anti-I (3.2%), an anti-M and an anti-N (0.36% each one). In 43 (15.4%) cases, we were not able to identify the specificity of the antibody found. We include a discussion and a comparison of the frequency of these antibodies in our population. Based on these data, we recommend the clinician to consider the existence and specificity of the irregular anti-erythrocytic antibodies in their obstetric patients, candidates to transfusional therapy, as well as those newborn with hemolytic diseases.

  2. [Immune hemolytic diseases caused by irregular antibodies and its research advance in clinic]. (United States)

    Zhang, Chen-Guang; Wang, Hui


    The irregular antibodies are other than antibodies from ABO blood group system because of pregnancies and blood transfusions, clinical autoimmune, drug-induced etc. The irregular IgG and/or IgM antibodies emerge and lead to the difficult identification of clinical blood type, difficult matching of blood, hemolytic disease of newborn, hemolytic transfusion reaction, and so on. It is very necessary to screen and identify the irregular antibodies before blood transfusion or antepartum. For some difficult identifying samples, some detections on serological level should be done firstly, combining with flow cytometry analysis, the difficult-matching patients' genotypes and fetal genotypes were detected by molecular biology techniques such as PCR and PCR-SSP in order to further predict fetal hemolytic disease of newborn and to provide the right blood to difficult-matching patients, and free fetal DNA extracted from maternal plasma. So that some measures must early be taken for clinical prevention and treatment to reduce immune hemolytic reactions. In this paper, the emergence of irregular antibodies, species, laboratory testing, pathogenesis, clinical symptoms and the current research are reviewed.

  3. Modelling the Cost Performance of a Given Logistics Network Operating Under Regular and Irregular Conditions

    NARCIS (Netherlands)

    Janic, M.


    This paper develops an analytical model for the assessment of the cost performance of a given logistics network operating under regular and irregular (disruptive) conditions. In addition, the paper aims to carry out a sensitivity analysis of this cost with respect to changes of the most influencing

  4. Ince-Strutt stability charts for ship parametric roll resonance in irregular waves (United States)

    Zhang, Xiao; Yang, He-zhen; Xiao, Fei; Xu, Pei-ji


    Ince-Strutt stability chart of ship parametric roll resonance in irregular waves is conducted and utilized for the exploration of the parametric roll resonance in irregular waves. Ship parametric roll resonance will lead to large amplitude roll motion and even wreck. Firstly, the equation describing the parametric roll resonance in irregular waves is derived according to Grim's effective theory and the corresponding Ince-Strutt stability charts are obtained. Secondly, the differences of stability charts for the parametric roll resonance in irregular and regular waves are compared. Thirdly, wave phases and peak periods are taken into consideration to obtain a more realistic sea condition. The influence of random wave phases should be taken into consideration when the analyzed points are located near the instability boundary. Stability charts for different wave peak periods are various. Stability charts are helpful for the parameter determination in design stage to better adapt to sailing condition. Last, ship variables are analyzed according to stability charts by a statistical approach. The increase of the metacentric height will help improve ship stability.

  5. Free Form Structural Design : Schemes, systems and prototypes of structures for irregular shaped buildings

    NARCIS (Netherlands)

    Veltkamp, M.


    Irregularly shaped buildings with double curved surfaces, also known as free forms or Blobs, have regained interest from architects. Those actually built however, despite their futuristic look, have load-bearing structures which are still based on conventional principles, as building systems

  6. Spherical and irregular aberrations are important for the optimal performance of the human eye

    NARCIS (Netherlands)

    Nio, YK; Jansonius, NM; Fidler, [No Value; Geraghty, E; Norrby, S; Kooijman, AC

    Contrast sensitivity measured psychophysically at different levels of defocus can be used to evaluate the eye optics. Possible parameters of spherical and irregular aberrations, e.g, relative modulation transfer (RMT), myopic shift, and depth of focus, can be determined from these measurements. The

  7. A Time-Domain Method for Separating Incident and Reflected Irregular Waves

    DEFF Research Database (Denmark)

    Frigaard, Peter; Brorsen, Michael

    of the model test. Goda and Suzuki (1976) presented a frequency method for estimation of irregular incident and reflected waves in random waves. Mansard and Funke (1980) improved this method uaing a least squares technique. In the following, a time-domain method for seperating the incident waves...

  8. Frustum-Traced Irregular Z-Buffers: Fast, Sub-pixel Accurate Hard Shadows. (United States)

    Wyman, Chris; Hoetzlein, Rama; Lefohn, Aaron


    We further describe and analyze a real-time system for rendering antialiased hard shadows using irregular z-buffers (IZBs) that we first presented in Wyman et al. [1]. We focus on identifying bottlenecks, exploring these from an algorithmic complexity standpoint, and presenting techniques to improve performance. Our system remains interactive on a variety of game assets and CAD models while running at resolutions 1920 1080 and above and imposes no constraints on light, camera or geometry, allowing fully dynamic scenes without precomputation. We render sub-pixel accurate, 32 sample per pixel hard shadows at roughly twice the cost of a single sample per pixel. This allows us to smoothly animate even subpixel shadows from grass or wires without introducing spatial or temporal aliasing. Prior algorithms for irregular z-buffer shadows rely heavily on the GPU's compute pipeline. Instead we leverage the standard rasterization-based graphics pipeline, including hardware conservative raster and early-z culling. Our key observation is noting a duality between irregular z-buffer performance and shadow map quality; irregular z-buffering is most costly exactly where shadow maps exhibit the worst aliasing. This allows us to use common shadow map algorithms, which typically improve aliasing, to instead reduce our cost. Compared to state of the art ray tracers, we spawn similar numbers of triangle intersections per pixel yet completely rebuild our data structure in under 1 ms per frame.

  9. The structure of plasma-density irregularities in the interplanetary medium

    International Nuclear Information System (INIS)

    Singleton, D.G.


    The conflict in the literature as to whether the plasma-density spatial spectrum of the irregularities in the interplanetary medium is of Gaussian or power law form is discussed. Particular attention is paid to the interplanetary scintillation effects ascribed to these irregularities. It is shown that the phase-screen theory of scintillations can be invoked to devise a set of critical tests which provide a means of discriminating between the conflicting hypotheses. Differences in the predicted behaviour of the single sensor temporal spectra of the scintillations for the two irregularity forms provide the main tests of the conflicting hypotheses. However, it is also shown that the two hypotheses lead to different forms of the variation of scintillation index with the observing frequency and the solar elongation of the scintillating source. Consideration is given to the optimum conditions for observing the Fourier and Bessel temporal spectra modulation which is due to the Fresnel filtering of the spatial spectrum. Determination of irregularity shape, orientation and motion in terms of this modulation is also discussed. (author)


    Energy Technology Data Exchange (ETDEWEB)

    Jiang, Yu [State Key Laboratory of Astronautic Dynamics, Xi’an Satellite Control Center, Xi’an 710043 (China); Baoyin, Hexi, E-mail: [School of Aerospace Engineering, Tsinghua University, Beijing 100084 (China)


    The discovery of binary and triple asteroids in addition to the execution of space missions to minor celestial bodies in the past several years have focused increasing attention on periodic orbits around irregular-shaped celestial bodies. In the present work, we adopt a polyhedron shape model for providing an accurate representation of irregular-shaped bodies and employ the model to calculate their corresponding gravitational and effective potentials. We also investigate the characteristics of periodic orbit families and the continuation of periodic orbits. We prove a fact, which provides a conserved quantity that permits restricting the number of periodic orbits in a fixed energy curved surface about an irregular-shaped body. The collisions of Floquet multipliers are maintained during the continuation of periodic orbits around the comet 1P/Halley. Multiple bifurcations in the periodic orbit families about irregular-shaped bodies are also discussed. Three bifurcations in the periodic orbit family have been found around the asteroid 216 Kleopatra, which include two real saddle bifurcations and one period-doubling bifurcation.

  11. The governance of international migration in Turkey and Morocco: Irregular migrants’ access to right to stay

    NARCIS (Netherlands)

    Üstübici Önay, A.E.


    This thesis analyses migrant experiences of illegality in Turkey and Morocco by taking into account how both countries responded to increasing pressure by the European Union to govern irregular migration within their territories. In dialogue with literatures on the legal production of migrant

  12. A Novel Energy Yields Calculation Method for Irregular Wind Farm Layout

    DEFF Research Database (Denmark)

    Hou, Peng; Hu, Weihao; Soltani, Mohsen


    Due to the increasing size of offshore wind farm, the impact of the wake effect on energy yields become more and more evident. The Seafloor topography would limit the layout of the wind farm so that irregular layout is usually adopted inlarge scale offshore wind farm. However, the calculation...

  13. Influence of Surface Irregularities on the Dynamic Response of Minor Highway Bridges

    DEFF Research Database (Denmark)

    Nielsen, Søren R. K.; Kirkegaard, Poul Henning

    In the present paper the effect on the dynamic application factor of bridge response from the surface irregularities is investigated. A numerical 3D model has been formulated for a 48t Scania truck. Further, a characteristic minor highway bridge has been selected, and a numerical FEM-model has been...

  14. Why pinning by surface irregularities can explain the peak effect in ...

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics; Volume 66; Issue 1. Why pinning by surface irregularities can explain the peak effect in transport properties and neutron diffraction results in NbSe2 and Bi-2212 crystals? Charles Simon Alain Pautrat Christophe Goupil Joseph Scola Patrice Mathieu Annie Brûlet Antoine ...

  15. An Irregular Grid Approach for Pricing High-Dimensional American Options

    NARCIS (Netherlands)

    Berridge, S.J.; Schumacher, J.M.


    We propose and test a new method for pricing American options in a high-dimensional setting.The method is centred around the approximation of the associated complementarity problem on an irregular grid.We approximate the partial differential operator on this grid by appealing to the SDE

  16. A new method of spatial analysis of irregularly spaced HLB data and biological implications (United States)

    Field data on intensity of plant diseases is very often irregularly spaced (i.e., there are varying amounts of distance between rows, ponds, voids, roads, houses, or other land areas). A new method of analysis, sometimes called second-generation wavelet analysis, can be used on this type of irregula...

  17. Irregular migration and informal economy in Southern and Central-Eastern Europe: breaking the vicious cycle? (United States)

    Maroukis, Thanos; Iglicka, Krystyna; Gmaj, Katarzyna


    The flexible and cheap labour that European “post-industrial” economies are in need of is often facilitated by undeclared labour. The undocumented migrant, from his/her part, relatively easily finds work that suits his -- at least initial -- plans. What lies behind this nexus between irregular migration and informal economy? To what extent can this nexus be attributed to the structural features of the so-called “secondary”, as opposed to “primary”, labour market? And how does migration policy correlate with this economic context and lead to the entrapment of migrants in irregularity? Finally, can this vicious cycle of interests and life-strategies be broken and what does the experience of the migrants indicate in this respect? This paper addresses these questions via an exploration of the grounds upon which irregular migration and the shadow economy complement each other in southern Europe (SE) and central and Eastern Europe (CEE) (two regions at different points in the migration cycle). In doing so, the dynamic character of the nexus between informal economy and irregular migration will come to the fore, and the abstract identity of the “average” undocumented migrant will be deconstructed.

  18. Time-accurate AB-simulations of irregular coastal waves above bathymetry

    NARCIS (Netherlands)

    van Groesen, Embrecht W.C.; Andonowati, A.; Lee, Joseph Hun-Wei; Ng, Chiu-On


    In this contribution the performance is shown of a hybrid spectral-spatial implementation of the AB model for uni-directional waves above varying bottom. For irregular waves of JONSWAP-type, with peak periods of 9 and 12[s], significant wave height of 3[m], running from 30 to 15[m] depth over a 1:20

  19. Menstrual Irregularities and Related Plasma Hormone Levels in Multiple Sclerosis Patients Treated with Beta Interferone

    Directory of Open Access Journals (Sweden)

    Ehya Garshasbi


    Full Text Available Multiple sclerosis is a chronic inflammatory disease of central nervous system.Women are more susceptible to this disease. One of the obvious clinical complaints in women with multiple sclerosis specially treated with Beta Interferones is menstrual cycle irregularity. The aim of this study was to determine the prevalence of menstrual irregularities and probable changes in blood levels of related hormones (FSH, LH, PRL, TSH, T4, T3 in 58 females with definite MS treated with beta interferones versus 58 healthy women. In comparison to the control group, the patients had higher prevalence of irregular menstruation (P=0.001, oligomenorrhea (p=0.03, abnormal amount of menstrual blood flow (P=0.001, abnormal duration of menstrual flow (P=0.01 and missed period (P=0.04. Mean LH level in patients group was higher than control group (P=0.04.Hyperprolactinemia (>25.5ng/ml was more prevalent in patients group .There were not a significant difference in plasma levels of FSH and thyroid hormones between two groups. There were some relations between the type of Beta interferones and the subtype of menstrual irregularities in the patients. In conclusion, the results of this study emphasized the high rate of menstrual problem and changes of related plasma hormone levels in MS patients.

  20. Local climatological modeling of ionospheric irregularities detected by GPS in the mid-latitude region (United States)

    Wautelet, G.; Warnant, R.


    Global Positioning System, or GPS, plays an important role in everyday life. More particularly, precise positioning applications constitute a continuously growing sector whose surveyors, civil engineers and more recently farmers represent the principal users. Ionospheric irregularities are considered as the main threat for those applications as their occurrence and their effects on positioning are generally unknown or unmodeled. This paper aims at setting up a local climatological model of such irregularities which can be used as a forecasting tool. The model is based upon a time series of GPS-derived ionospheric irregularities in Belgium covering 10 years of data (period 2002-2011). Our climatological model is twofold: its first component describes the daily variability and is derived from a principal component analysis (PCA) which allows us to retrieve the main patterns of the time series. With the use of low order polynomial and harmonic functions, the second component describes the influence of solar cycle and seasons on irregularity occurrence. Moreover, a statistical autoregressive formulation adapts the model to current conditions. Model validation covers both low and active solar activity periods (years 2008 and 2011) and shows that model accuracy varies with solar conditions and season: values are lower during winter and active solar activity periods, where modeling error can reach up to 60% of the observed value. During summer, model performance is clearly improved, with relative errors generally smaller than 20% for periods of low but also active solar activity.

  1. Analysis of Mid-Latitude Plasma Density Irregularities in the Presence of Finite Larmor Radius Effects (United States)

    Sotnikov, V. I.; Kim, T. C.; Mishin, E. V.; Kil, H.; Kwak, Y. S.; Paraschiv, I.


    Ionospheric irregularities cause scintillations of electromagnetic signals that can severely affect navigation and transionospheric communication, in particular during space storms. At mid-latitudes the source of F-region Field Aligned Irregularities (FAI) is yet to be determined. They can be created in enhanced subauroral flow channels (SAI/SUBS), where strong gradients of electric field, density and plasma temperature are present. Another important source of FAI is connected with Medium-scale travelling ionospheric disturbances (MSTIDs). Related shear flows and plasma density troughs point to interchange and Kelvin-Helmholtz type instabilities as a possible source of plasma irregularities. A model of nonlinear development of these instabilities based on the two-fluid hydrodynamic description with inclusion of finite Larmor radius effects will be presented. This approach allows to resolve density irregularities on the meter scale. A numerical code in C language to solve the derived nonlinear equations for analysis of interchange and flow velocity shear instabilities in the ionosphere was developed. This code will be used to analyze competition between interchange and Kelvin-Helmholtz instabilities in the mid-latitude region. The high-resolution simulations with continuous density and velocity profiles will be driven by the ambient conditions corresponding to the in situ data obtained during the 2016 Daejeon (Korea) and MU (Japan) radar campaign and data collected simultaneously by the Swarm satellites passed over Korea and Japan. PA approved #: 88ABW-2017-3641

  2. On initial enhancement of mesospheric dust associated plasma irregularities subsequent to radiowave heating

    Directory of Open Access Journals (Sweden)

    W. A. Scales


    Full Text Available Important observational manifestations of subvisible mesospheric dust are Polar Mesospheric Summer Echoes PMSE which are produced by scattering from electron irregularities produced by dust charging. It has been observed that the PMSE strength can be artificially modified by using a ground-based ionospheric heating facility to perturb the electron irregularity source region that is believed to produce PMSE. Recently it has become evident that significant diagnostic information may be available about the dust layer from the temporal behavior of the electron irregularities during the heating process which modifies the background electron temperature. Particularly interesting and important periods of the temporal behavior are during the turn-on and turn-off of the radiowave heating. Although a number of past theoretical and experimental investigations have considered the turn-off period, the objective here is to consider futher possibilities for diagnostic information available as well as the underlying physical processes. Approximate analytical models are developed and compared to a more accurate full computational model as a reference. Then from the temporal behavior of the electron irregularities during the turn-off of the radiowave heating, the analytical models are used to obtain possible diagnostic information for various charged dust and background plasma quantities.

  3. Eddy current heating of irregularly shaped plates by slow ramped fields

    International Nuclear Information System (INIS)

    Dresner, L.


    Theorems are presented for estimating eddy current heating of irregularly shaped plates by a perpendicular ramped field. The theorems, which are derived from two complementary variational principles, give upper and lower bounds to the eddy current heating. Illustrative results are given for rectangles, isosceles triangles, sectors of circular annuli, rhombuses, and L-shaped plates. A comparison is made with earlier work

  4. Gait Characteristics Associated with Trip-Induced Falls on Level and Sloped Irregular Surfaces

    Directory of Open Access Journals (Sweden)

    Andrew Merryweather


    Full Text Available Same level falls continue to contribute to an alarming number of slip/trip/fall injuries in the mining workforce. The objective of this study was to investigate how walking on different surface types and transverse slopes influences gait parameters that may be associated with a trip event. Gait analysis was performed for ten subjects on two orientations (level and sloped on smooth, hard surface (control and irregular (gravel, larger rocks surfaces. Walking on irregular surfaces significantly increased toe clearance compared to walking on the smooth surface. There was a significant (p < 0.05 decrease in cadence (steps/min, stride length (m, and speed (m/s from control to gravel to larger rocks. Significant changes in external rotation and increased knee flexion while walking on irregular surfaces were observed. Toe and heel clearance requirements increased on irregular surfaces, which may provide an explanation for trip-induced falls; however, the gait alterations observed in the experienced workers used as subjects would likely improve stability and recovery from a trip.

  5. Mental health care for irregular migrants in Europe: Barriers and how they are overcome

    NARCIS (Netherlands)

    Straßmayr, Christa; Matanov, Aleksandra; Priebe, Stefan; Barros, Henrique; Canavan, Reamonn; Díaz-Olalla, José Manuel; Gabor, Edina; Gaddini, Andrea; Greacen, Tim; Holcnerová, Petra; Kluge, Ulrike; Welbel, Marta; Nicaise, Pablo; Schene, Aart H.; Soares, Joaquim J. F.; Katschnig, Heinz


    Background: Irregular migrants (IMs) are exposed to a wide range of risk factors for developing mental health problems. However, little is known about whether and how they receive mental health care across European countries. The aims of this study were (1) to identify barriers to mental health care

  6. Influence of initial stress, irregularity and heterogeneity on Love-type ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Earth System Science; Volume 124; Issue 7 ... The effect of size and shape of irregularity, horizontal compressive initial stress, horizontal tensile initial stress, heterogeneity of the uppermost layer and width ratio of the layers on phase velocity of Love-type wave are the major highlights of the study.

  7. Ground- and Space-Based Observations of Ionospheric Irregularities over Nigeria during Solar Minimum (United States)

    Carrano, C. S.; Yizengaw, E.; Doherty, P. H.; Bridgwood, C. T.; Adeniyi, J. O.; Amaeshi, L. L.; Pedersen, T. R.; Groves, K. M.; Roddy, P. A.; Caton, R. G.


    Ionospheric irregularities and plasma turbulence can cause scintillation in the amplitude and phase of trans-ionospheric radio waves employed by satellite navigation and communication systems, leading to a degradation of system performance. Due to the relatively sparse distribution of ground-based ionospheric monitoring instruments in Africa, the climatology and morphology of ionospheric irregularities over Africa have not been adequately characterized. Boston College, Air Force Research Laboratory, and the Universities of Ilorin and Lagos in Nigeria have collaborated to operate two high-rate GPS receivers capable of monitoring both Total Electron Content (TEC) and scintillation intensity. We use GPS measurements collected from 2007-2009 to 1) identify ionospheric irregularities and quantify their spatial extent, 2) estimate the zonal drift velocity by cross-correlating TEC measurements between pairs of GPS satellites, 3) relate ionospheric irregularities to the occurrence of weak scintillation at the GPS L1 frequency, 4) characterize the strength of amplitude and phase scintillations in terms of their power spectral densities, and 5) use phase screen theory to predict the intensity of scintillation that would be observed by ionospheric monitoring sensors operating at lower frequencies. Measurements of plasma density and zonal drift from the C/NOFS satellite during passes over Nigeria are used to corroborate and complement these ground-based GPS observations.

  8. Non-destructive analysis of small irregularly shaped homogenous samples by X-ray fluorescence spectrometry

    NARCIS (Netherlands)

    Bos, M.; Vrielink, J.A.M.; van der Linden, W.E.


    A new calibration procedure is proposed for the non-destructive analysis of small sized samples of irregular shape by X-ray fluorescence spectrometry. The calibration is performed using normal calibration standards and measurements. The calculations for the calibration and the analysis of unknown

  9. Two media method for linear attenuation coefficient determination of irregular soil samples

    International Nuclear Information System (INIS)

    Vici, Carlos Henrique Georges


    In several situations of nuclear applications, the knowledge of gamma-ray linear attenuation coefficient for irregular samples is necessary, such as in soil physics and geology. This work presents the validation of a methodology for the determination of the linear attenuation coefficient (μ) of irregular shape samples, in such a way that it is not necessary to know the thickness of the considered sample. With this methodology irregular soil samples (undeformed field samples) from Londrina region, north of Parana were studied. It was employed the two media method for the μ determination. It consists of the μ determination through the measurement of a gamma-ray beam attenuation by the sample sequentially immersed in two different media, with known and appropriately chosen attenuation coefficients. For comparison, the theoretical value of μ was calculated by the product of the mass attenuation coefficient, obtained by the WinXcom code, and the measured value of the density sample. This software employs the chemical composition of the samples and supplies a table of the mass attenuation coefficients versus the photon energy. To verify the validity of the two media method, compared with the simple gamma ray transmission method, regular pome stone samples were used. With these results for the attenuation coefficients and their respective deviations, it was possible to compare the two methods. In this way we concluded that the two media method is a good tool for the determination of the linear attenuation coefficient of irregular materials, particularly in the study of soils samples. (author)

  10. Understanding Technology?

    Directory of Open Access Journals (Sweden)

    Erik Bendtsen


    Full Text Available We are facing radical changes in our ways of living in the nearest future. Not necessarily of our own choice, but because tchnological development is moving so fast, that it will have still greater impact on many aspects of our lives. We have seen the beginnings of that change within the latest 35 years or so, but according to newest research that change will speed up immensely in the nearest years to come. The impact of that change or these changes will affect our working life immensely as a consequence of automation. How these changes are brought about and which are their consequences in a broad sense is being attempted to be understood and guessed by researchers. No one knows for sure, but specific patterns are visible. This paper will not try to guess, what will come, but will rather try to understand the deepest ”nature” of technology in order to understand the driving factors in this development: the genesis of technology in a broad sense in order to contibute to the understanding of the basis for the expected development.

  11. [Analysis of Patients' Irregular Antibody Screening and Identification Results before Blood Transfusion]. (United States)

    Li, Hui; Xu, Huan-Ming; Zhang, Yi; Cui, Ji-Xiang


    To analyze the results of irregular antibody screening and identification among patients before blood transfusion, and to investigate the specific distribution of irregular antibodies and the distribution regularity in different diseases. Choosing the patients intended to be transfused in our hospital from January 1, 2009 to December 31, 2013 years, micro-column gel technique was used to screen the irregular antibodies of those receptors and to identify the antibody specificity of the positive specimens. Among 44194 patients, 137 patients were with irregular antibody positive and their positive rate was 0.31%, among them 33 cases were male and accounted for 0.18% in the studied males; the 104 cases were females and accounted for 0.40% in all the studied females. The difference of sex distribution was statistically significant (X2=15.38, Pirregular antibody screening positive patients, patients with transfusion or pregnancy history were 129 cases, and the patients without transfusion or pregnancy history were 8 cases. In the irregular antibody screening positive patients, the main antibody of 54 cases belongs to Rh blood type system, accounting for 39.42%; The main antibody of 37 cases belongs to MNS blood type system, accounting for 27.01%; while the 30 cases belong to Lewis blood type system, accounting for 21.90%. According to the classification of diseases, the irregular antibody screening-positive patients with tumors were ranked in the highest rate at 5.96‰, the secondary hemorrhage of digestive tract and chronic renal failure were ranked at the rate of 3.28‰ and 3.19‰. The difference of positive rates between diseases was statistically significant (χ2=19.33, PIrregular antibody screening before blood transfusion is necessary, which can discover the irregular antibodies of clinical significance, especially for patients with tumors and the other patients with the history of frequent blood transfusions or multiple pregnancies. Antibody screening is a

  12. Effects of irregular-shift work and physical activity on cardiovascular risk factors in truck drivers

    Directory of Open Access Journals (Sweden)

    Elaine Cristina Marqueze


    Full Text Available OBJECTIVE: To analyze the putative effect of type of shift and its interaction with leisure-time physical activity on cardiovascular risk factors in truck drivers. METHODS: A cross-sectional study was undertaken on 57 male truck drivers working at a transportation company, of whom 31 worked irregular shifts and 26 worked on the day-shift. Participants recorded their physical activity using the International Physical Activity Questionnaire along with measurements of blood pressure, body mass index and waist-hip ratio. Participants also provided a fasting blood sample for analysis of lipid-related outcomes. Data were analyzed using a factorial model which was covariate-controlled for age, smoking, work demand, control at work and social support. RESULTS: Most of the irregular-shift and day-shift workers worked more than 8 hours per day (67.7% and 73.1%, respectively. The mean duration of experience working the irregular schedule was 15.7 years. Day-shift workers had never engaged in irregular-shift work and had been working as a truck driver for 10.8 years on average. The irregular-shift drivers had lower work demand but less control compared to day-shift drivers (p < 0.05. Moderately-active irregular-shift workers had higher systolic and diastolic arterial pressures (143.7 and 93.2 mmHg, respectively than moderately-active day-shift workers (116 and 73.3 mmHg, respectively (p < 0.05 as well as higher total cholesterol concentrations (232.1 and 145 mg/dl, respectively (p = 0.01. Irrespective of their physical activity, irregular-shift drivers had higher total cholesterol and LDL-cholesterol concentrations (211.8 and 135.7 mg/dl, respectively than day-shift workers (161.9 and 96.7 mg/dl, respectively (ANCOVA, p < 0.05. CONCLUSIONS: Truck drivers are exposed to cardiovascular risk factors due to the characteristics of the job, such as high work demand, long working hours and time in this profession, regardless of shift type or leisure-time physical

  13. The effect of earthquake on architecture geometry with non-parallel system irregularity configuration (United States)

    Teddy, Livian; Hardiman, Gagoek; Nuroji; Tudjono, Sri


    Indonesia is an area prone to earthquake that may cause casualties and damage to buildings. The fatalities or the injured are not largely caused by the earthquake, but by building collapse. The collapse of the building is resulted from the building behaviour against the earthquake, and it depends on many factors, such as architectural design, geometry configuration of structural elements in horizontal and vertical plans, earthquake zone, geographical location (distance to earthquake center), soil type, material quality, and construction quality. One of the geometry configurations that may lead to the collapse of the building is irregular configuration of non-parallel system. In accordance with FEMA-451B, irregular configuration in non-parallel system is defined to have existed if the vertical lateral force-retaining elements are neither parallel nor symmetric with main orthogonal axes of the earthquake-retaining axis system. Such configuration may lead to torque, diagonal translation and local damage to buildings. It does not mean that non-parallel irregular configuration should not be formed on architectural design; however the designer must know the consequence of earthquake behaviour against buildings with irregular configuration of non-parallel system. The present research has the objective to identify earthquake behaviour in architectural geometry with irregular configuration of non-parallel system. The present research was quantitative with simulation experimental method. It consisted of 5 models, where architectural data and model structure data were inputted and analyzed using the software SAP2000 in order to find out its performance, and ETAB2015 to determine the eccentricity occurred. The output of the software analysis was tabulated, graphed, compared and analyzed with relevant theories. For areas of strong earthquake zones, avoid designing buildings which wholly form irregular configuration of non-parallel system. If it is inevitable to design a

  14. Effects of irregular two-dimensional and three-dimensional surface roughness in turbulent channel flows

    International Nuclear Information System (INIS)

    De Marchis, M.; Napoli, E.


    Highlights: ► 3D irregular rough surfaces produce higher effects than those observed over 2D. ► Effective slope is a geometrical parameter representative of the roughness effects. ► 3D rough surfaces enhance the turbulence isotropization. ► 2D and 3D irregular roughness partially support the wall similarity. ► Irregular rough surfaces shear some features with regular rough walls. - Abstract: Wall-resolved Large Eddy Simulation of fully developed turbulent channel flows over two different rough surfaces is performed to investigate on the effects of irregular 2D and 3D roughness on the turbulence. The two geometries are obtained through the superimposition of sinusoidal functions having random amplitudes and different wave lengths. In the 2D configuration the irregular shape in the longitudinal direction is replicated in the transverse one, while in the 3D case the sinusoidal functions are generated both in streamwise and spanwise directions. Both channel walls are roughened in such a way as to obtain surfaces with statistically equivalent roughness height, but different shapes. In order to compare the turbulence properties over the two rough walls and to analyse the differences with a smooth wall, the simulations are performed at the same Reynolds number Re τ = 395. The same mean roughness height h = 0.05δ (δ the half channel height) is used for the rough walls. The roughness function obtained with the 3D roughness is larger than in the 2D case, although the two walls share the same mean height. Thus, the considered irregular 3D roughness is more effective in reducing the flow velocity with respect to the 2D roughness, coherently with the literature results that identified a clear dependence of the roughness function on the effective slope (see ), higher in the generated 3D rough wall. The analysis of higher-order statistics shows that the effects of the roughness, independently on its two- or three-dimensional shape, are mainly confined in the inner

  15. A study on the status of and factors in irregular menstruation in university students

    Directory of Open Access Journals (Sweden)

    Tuba Ucar


    Methods: The present descriptive study was conducted at Health College of Inonu University between November 15 and December 01, 2012. The population was comprised of a total of 678 female students who studied Midwifery (n=212 and Nursing (n=466. No specific sample was chosen; therefore, all the participants were included within the scope of the study. However, the sample was comprised of a total of 365 students who volunteered to participate in the study. The data were obtained through the and ldquo;Personal Information Form and rdquo; and analyzed via such statistics as Pearson's Chi-Squared test, Fisher's exact test and t-test for independent groups. Results: The mean age of the participants was 20.28+/-1.99. While 46% of them studied midwifery, the remaining 54% studied nursing. The mean menarche age was 13.45+/-1.55 whereas the mean menstruation length was 5.61+/-1.88. The prevalence of irregular menstruation in the students was 23.8%. The study could not yield a correlation between irregular menstruation and age, presence of chronic disease and average daily sleep time with irregular menstruation (p>0.05. Those students who do not exercise regularly, had psychiatric disorders, regular drug users, in users of oral contraceptives, smoked and had higher Body-Mass Indices were more likely to suffer from irregular menstruation (p<0.05. Conclusions: The study concluded that nearly one-fourth of the students had irregular menstruation. The finding is promising inthat all these risk factors (obesity, smoking, sedentary living, medication and oral contraceptive use are avoidablewith changes in behaviors, for which healthcare professionals are significantly responsible [TAF Prev Med Bull 2015; 14(3.000: 215-221

  16. Refraction traveltime tomography based on damped wave equation for irregular topographic model (United States)

    Park, Yunhui; Pyun, Sukjoon


    Land seismic data generally have time-static issues due to irregular topography and weathered layers at shallow depths. Unless the time static is handled appropriately, interpretation of the subsurface structures can be easily distorted. Therefore, static corrections are commonly applied to land seismic data. The near-surface velocity, which is required for static corrections, can be inferred from first-arrival traveltime tomography, which must consider the irregular topography, as the land seismic data are generally obtained in irregular topography. This paper proposes a refraction traveltime tomography technique that is applicable to an irregular topographic model. This technique uses unstructured meshes to express an irregular topography, and traveltimes calculated from the frequency-domain damped wavefields using the finite element method. The diagonal elements of the approximate Hessian matrix were adopted for preconditioning, and the principle of reciprocity was introduced to efficiently calculate the Fréchet derivative. We also included regularization to resolve the ill-posed inverse problem, and used the nonlinear conjugate gradient method to solve the inverse problem. As the damped wavefields were used, there were no issues associated with artificial reflections caused by unstructured meshes. In addition, the shadow zone problem could be circumvented because this method is based on the exact wave equation, which does not require a high-frequency assumption. Furthermore, the proposed method was both robust to an initial velocity model and efficient compared to full wavefield inversions. Through synthetic and field data examples, our method was shown to successfully reconstruct shallow velocity structures. To verify our method, static corrections were roughly applied to the field data using the estimated near-surface velocity. By comparing common shot gathers and stack sections with and without static corrections, we confirmed that the proposed tomography

  17. Topography-guided laser in situ keratomileusis (TOPOLINK) to correct irregular astigmatism after previous refractive surgery. (United States)

    Alió, Jorge L; Belda, Jose I; Osman, Amr A; Shalaby, Ahmad M M


    To assess whether topography-driven laser in situ keratomileusis (LASIK) can correct induced corneal irregular astigmatism. A prospective non-comparative case series of 41 eyes (38 patients) with irregular astigmatism following corneal refractive surgery, included two groups: Group 1 (26 eyes) with a defined topographic pattern and Group 2 (15 eyes) with no pattern. Ablation was performed using the Technolas 217C excimer laser with a software ablation program (TOPOLINK) based on corneal topography. Uncorrected and best spectacle-corrected visual acuity, manifest and cycloplegic refraction, corneal topography, superficial corneal surface quality, and image distortion were measured. At 6 months follow-up in Group 1 eyes (defined topographic pattern) mean preoperative BSCVA improved from 0.16 +/- 0.11 LogMAR (0.4 to 0) to 0.09 +/- 0.10 LogMAR (0.2 to 0) (P = .001) (safety index of 1.1). In Group 2 eyes (no pattern), mean preoperative BSCVA was 0.18 +/- 0.11 LogMAR (0.4 to 0), similar to the postoperative BSCVA of 0.17 +/- 0.10 LogMAR (0.3 to 0) (safety index of 0.98). Mean postoperative UCVA was > or = 0.3 LogMAR in 25 eyes (96.2%) in Group 1 (efficacy index of 0.8) and 7 eyes (46.6%) in Group 2 (efficacy index of 0.5). Both superficial corneal surface quality and image distortion significantly improved in Group 1; there were no significant changes in Group 2. We reoperated nine eyes (21.9%). Topographic-assisted LASIK was helpful in selected cases where irregular astigmatism showed a pattern. It was ineffective in undefined irregular astigmatism. Partial correction of the irregularity and regression of the obtained effect was common.

  18. Irregular plate boundary controls on Foreland Basin sedimentation (Miocene, Kahramanmaraş Foreland Basin, SE Turkey) (United States)

    Gül, Murat; Gürbüz, Kemal; Cronin, Bryan T.


    The northern movement of the Arabian Plate led to the development of a compressional regime in the south-eastern part of Turkey after the Late Cretaceous. The collision of the Arabian Plate with the Anatolide-Taurides Platform and subsequent development of the Kahramanmaraş Foreland Basin at the beginning of the Miocene evolved as a result of this movement. An irregular plate geometry or promontory of the Arabian Plate caused partitioning of the plate margin (precollision-collision-postcollision). This irregular plate boundary was delimited by western and northern boundary faults and an interior basin fault. The NW-oriented small wedge top basins on the overlying Anatolide-Taurides Platform obliquely cut through the foredeep basin. The region (across the wedge top basin) on the irregular promontory of the underlying Arabian Plate contains different sedimentation depocentres. Small fining-upward submarine fan deposits (including pebbly channel deposits and coarsening-upward lobe sequences) are located at the centre of the irregular part of the plate (in the Tanır region) and overlie planktic foraminifera-bearing claystones. These submarine fan sediments pass outboard into distal interbedded turbidite claystones and siltstones in a downdip direction (S-SE). The boundary fault intersection of the promontory led to the development of a submarine slope environment with irregular sea-floor topography in the Fırnız area (4-5 km south-east of the Tanır region). The slump deposits, sandy debrites, and fine-grained thin-bedded turbidites filled this region. Structural alignments and seismicity associated with the plate margin were the main controlling factors on the geometry of the depocentre, sediment quantity, sediment input, sedimentary facies, local sea level changes, and post-sedimentary deformation in the Kahramanmaraş Foreland Basin.

  19. Bayesian modeling of the covariance structure for irregular longitudinal data using the partial autocorrelation function. (United States)

    Su, Li; Daniels, Michael J


    In long-term follow-up studies, irregular longitudinal data are observed when individuals are assessed repeatedly over time but at uncommon and irregularly spaced time points. Modeling the covariance structure for this type of data is challenging, as it requires specification of a covariance function that is positive definite. Moreover, in certain settings, careful modeling of the covariance structure for irregular longitudinal data can be crucial in order to ensure no bias arises in the mean structure. Two common settings where this occurs are studies with 'outcome-dependent follow-up' and studies with 'ignorable missing data'. 'Outcome-dependent follow-up' occurs when individuals with a history of poor health outcomes had more follow-up measurements, and the intervals between the repeated measurements were shorter. When the follow-up time process only depends on previous outcomes, likelihood-based methods can still provide consistent estimates of the regression parameters, given that both the mean and covariance structures of the irregular longitudinal data are correctly specified and no model for the follow-up time process is required. For 'ignorable missing data', the missing data mechanism does not need to be specified, but valid likelihood-based inference requires correct specification of the covariance structure. In both cases, flexible modeling approaches for the covariance structure are essential. In this paper, we develop a flexible approach to modeling the covariance structure for irregular continuous longitudinal data using the partial autocorrelation function and the variance function. In particular, we propose semiparametric non-stationary partial autocorrelation function models, which do not suffer from complex positive definiteness restrictions like the autocorrelation function. We describe a Bayesian approach, discuss computational issues, and apply the proposed methods to CD4 count data from a pediatric AIDS clinical trial. © 2015 The Authors

  20. Understanding uncertainty

    CERN Document Server

    Lindley, Dennis V


    Praise for the First Edition ""...a reference for everyone who is interested in knowing and handling uncertainty.""-Journal of Applied Statistics The critically acclaimed First Edition of Understanding Uncertainty provided a study of uncertainty addressed to scholars in all fields, showing that uncertainty could be measured by probability, and that probability obeyed three basic rules that enabled uncertainty to be handled sensibly in everyday life. These ideas were extended to embrace the scientific method and to show how decisions, containing an uncertain element, could be rationally made.

  1. Analytical modeling of the statistical properties of the contrast of large-scale irregularities of the ionosphere (United States)

    Vsekhsviatskaia, I. S.; Evstratova, E. A.; Kalinin, Iu. K.; Romanchuk, A. A.


    An analytical model is proposed for the distribution of variations of the relative contrast of the electron density of large-scale ionospheric irregularities. The model is characterized by nonzero asymmetry and excess. It is shown that the model can be applied to horizontal irregularity scales from hundreds to thousands of kilometers.

  2. Exploring Individual Differences in Irregular Word Recognition among Children with Early-Emerging and Late-Emerging Word Reading Difficulty (United States)

    Steacy, Laura M.; Kearns, Devin M.; Gilbert, Jennifer K.; Compton, Donald L.; Cho, Eunsoo; Lindstrom, Esther R.; Collins, Alyson A.


    Models of irregular word reading that take into account both child- and word-level predictors have not been evaluated in typically developing children and children with reading difficulty (RD). The purpose of the present study was to model individual differences in irregular word reading ability among 5th grade children (N = 170), oversampled for…

  3. Scanning electron microscopic assessment of coating irregularities and their precursors in unexpanded durable polymer-based drug-eluting stents

    NARCIS (Netherlands)

    Basalus, M.W.; Tandjung, K.; Tandjung, K.; van Westen, T.; Sen, H.; van der Jagt, P.K.N.; Grijpma, Dirk W.; van Apeldoorn, Aart A.; von Birgelen, Clemens


    Objectives: To assess and quantify coating irregularities on unexpanded and expanded durable polymer-based drug-eluting stents (DES) to gain insights into the origin of coating irregularities. Background: Previous scanning electron microscopy (SEM) studies in various expanded DES revealed

  4. Processing of Regular and Irregular Past-Tense Verb Forms in First and Second Language Reading Acquisition

    NARCIS (Netherlands)

    Zeeuw, E.M. de; Schreuder, R.; Verhoeven, L.T.W.


    We investigated written word identification of regular and irregular past-tense verb forms by first (L1) and second language (L2) learners of Dutch in third and sixth grade. Using a lexical decision task, we measured speed and accuracy in the identification of regular and irregular past-tense verb

  5. Understanding analysis

    CERN Document Server

    Abbott, Stephen


    This lively introductory text exposes the student to the rewards of a rigorous study of functions of a real variable. In each chapter, informal discussions of questions that give analysis its inherent fascination are followed by precise, but not overly formal, developments of the techniques needed to make sense of them. By focusing on the unifying themes of approximation and the resolution of paradoxes that arise in the transition from the finite to the infinite, the text turns what could be a daunting cascade of definitions and theorems into a coherent and engaging progression of ideas. Acutely aware of the need for rigor, the student is much better prepared to understand what constitutes a proper mathematical proof and how to write one. Fifteen years of classroom experience with the first edition of Understanding Analysis have solidified and refined the central narrative of the second edition. Roughly 150 new exercises join a selection of the best exercises from the first edition, and three more project-sty...

  6. Understanding ayurveda. (United States)

    Gadgil, Vaidya Dilip


    Ayurveda needs to achieve its full potential both in India and globally. This requires imparting to its students full appreciation of Ayurveda's power and strength, particularly proper understanding of the advantages of applying it to treat chronic and acute diseases. To this end, we explain the necessity of learning Sanskrit as a medium of study, and the advantages of learning the Texts in the traditional way, rather than relying on translations with all the loss of meaning and precision, which that entails. We emphasize the use of Triskandhakosha as a means to fully understand Ayurveda fundamental concepts and technical terms, so that all their shades of meaning are fully understood, and all their usages given in different places in the texts. Only by such methods can full appreciation of Ayurvedic wisdom be achieved, and the full depth and power of its knowledge be applied. Only then will its true status among systems of medicine come to be appreciated, either in India or more widely in the world as a whole.

  7. Understanding Ayurveda

    Directory of Open Access Journals (Sweden)

    Vaidya Dilip Gadgil


    Full Text Available Ayurveda needs to achieve its full potential both in India and globally. This requires imparting to its students full appreciation of Ayurveda′s power and strength, particularly proper understanding of the advantages of applying it to treat chronic and acute diseases. To this end, we explain the necessity of learning Sanskrit as a medium of study, and the advantages of learning the Texts in the traditional way, rather than relying on translations with all the loss of meaning and precision, which that entails. We emphasize the use of Triskandhakosha as a means to fully understand Ayurveda fundamental concepts and technical terms, so that all their shades of meaning are fully understood, and all their usages given in different places in the texts. Only by such methods can full appreciation of Ayurvedic wisdom be achieved, and the full depth and power of its knowledge be applied. Only then will its true status among systems of medicine come to be appreciated, either in India or more widely in the world as a whole.

  8. Experimental modelling of wave amplification over irregular bathymetry for investigations of boulder transport by extreme wave events. (United States)

    O'Boyle, Louise; Whittaker, Trevor; Cox, Ronadh; Elsäßer, Björn


    During the winter of 2013-2014 the west coast of Ireland was exposed to 6 storms over a period of 8 weeks with wind speeds equating to hurricane categories 3 and 4. During this period, the largest significant wave height recorded at the Marine Institute M6 wave buoy, approximately 300km from the site, was 13.6m (on 26th January 2014). However, this may not be the largest sea state of that winter, because the buoy stopped logging on 30th January and therefore failed to capture the full winter period. During the February 12th 2014 "Darwin" storm, the Kinsale Energy Gas Platform off Ireland's south coast measured a wave height of 25 m, which remains the highest wave measured off Ireland's coasts[1]. Following these storms, significant dislocation and transportation of boulders and megagravel was observed on the Aran Islands, Co. Galway at elevations of up to 25m above the high water mark and distances up to 220 m inland including numerous clasts with masses >50t, and at least one megagravel block weighing >500t [2]. Clast movements of this magnitude would not have been predicted from the measured wave heights. This highlights a significant gap in our understanding of the relationships between storms and the coastal environment: how are storm waves amplified and modified by interactions with bathymetry? To gain further understanding of wave amplification, especially over steep and irregular bathymetry, we have designed Froude-scaled wave tank experiments using the 3D coastal wave basin facility at Queen's University Belfast. The basin is 18m long by 16m wide with wave generation by means of a 12m wide bank of 24 top hinged, force feedback, sector carrier wave paddles at one end. The basin is equipped with gravel beaches to dissipate wave energy on the remaining three sides, capable of absorbing up to 99% of the incident wave energy, to prevent unwanted reflections. Representative bathymetry for the Aran Islands is modelled in the basin based on a high resolution

  9. Do morphophonological rules impact both regular and irregular verb inflection? Evidence from acquired morphological impairment

    Directory of Open Access Journals (Sweden)

    Stacey Rimikis


    Full Text Available Introduction The role of morphophonological rules in production is a frequent point of contention in competing theories of morphological processing. Dual-mechanism theories have posited that a single default rule (stem+ed is used to produce the regular past tense, while all other past-tense forms are memorized and retrieved whole. However, research has suggested that a series of stochastic morphophonological rules plays a role in morphological productivity for both regular and irregular novel verbs (e.g. Albright & Hayes, 2003. Under this view, the likelihood of a given rule applying to a verb is partially dependent on its lexical support, measured as the number of phonologically similar verbs in the lexicon which take the same inflectional change (e.g. weep→wept, sweep→swept, etc.. To date, most evidence supporting this view has come from the morphological productivity of novel forms (e.g. Albright & Hayes, 2003 and from visual word recognition (Fruchter, Stockall, & Marantz, 2013. The present study extends this work by demonstrating that morphophonological rules impact production more generally, including the production of both regular and irregular past tense in RMI, an aphasic individual with an established morphological deficit (Rimikis & Buchwald, 2014. While we previously reported differences in production for irregular verbs with either high or low levels of lexical support, the current study further examined this phenomenon, and we found that the production of the past-tense form for both regular and irregular verbs was affected by the support for that verb’s inflectional rule . Subject RMI, 39, right-handed male with aphasia secondary to L-MCA CVA. His production includes frequent morphological errors across tasks, with semantic and phonological errors also occurring. Procedure RMI was administered a past-tense elicitation task. Sentence frames including regular and irregular verbs were presented verbally and visually (e.g.

  10. Topographically-guided laser in situ keratomileusis to treat corneal irregularities. (United States)

    Knorz, M C; Jendritza, B


    To evaluate the predictability and safety of topographically guided laser in situ keratomileusis (LASIK) to treat corneal irregularities. Prospective, noncomparative interventional case series. Twenty-seven patients (29 eyes) with postsurgical corneal irregularities, divided into four subgroups (postkeratoplasty, 6 eyes; posttrauma, 6 eyes; postphotorefractive keratectomy (PRK)/LASIK with decentered or small ablations, 11 eyes; post-PRK/LASIK with central islands, 6 eyes). LASIK was performed using the Automatic Corneal Shaper and the Keracor 117 C spot-scanning excimer laser (Bausch & Lomb Surgical Technolas, Munich, Germany). Individual ablation patterns were calculated on the basis of axial radii of curvature data obtained with the Corneal Analysis System (EyeSys Premier, Irvine, CA). Change of corneal topography pattern, patient satisfaction, manifest spectacle refraction, and visual acuity at 12 months after surgery. Corneal topography showed improved corneal regularity in 66% of eyes in the postkeratoplasty group, whereas 34% remained irregular. In the posttrauma group, 83% improved and 17% remained irregular. In the decentered/small optical zone group, 91 % improved and 9% remained irregular. In the central islands group, 50% improved and 50% remained irregular. Refractive cylinder decreased from 5.83 +/- 1.25 diopters (D) to 2.96 +/- 1.23 D in the postkeratoplasty group (P = 0.01), from 2.21 +/- 1.35 D to 0.50 +/- 0.84 D in the posttrauma group (P = 0.001), from 0.73 +/- 0.71 D to 0.36 +/- 1.05 D in the decentered/small optical zone group (NS), and from 1.42 +/- 1.13 D to 0.50 +/- 0.84 D in the central island group (P = 0.01). Uncorrected visual acuity improved from 20/200 +/- 0.07 to 20/50 +/- 0.17 in the postkeratoplasty group (P = 0.01), from 20/83 +/- 0.12 to 20/50 +/- 0.28 in the posttrauma group (P = 0.01), from 20/60 +/- 0.16 to 20/50 +/- 0.29 in the decentered/small optical zone group (NS), and from 20/71 +/- 0.12 to 20/60 +/- 0.24 in the central

  11. Understanding physics

    CERN Document Server

    Cassidy, David; Rutherford, James


    Understanding Physics provides a thorough grounding in contemporary physics while placing physics into its social and historical context Based in large part on the highly respected Project Physics Course developed by two of the authors, it also integrates the results of recent pedagogical research The text thus - teaches about the basic phenomena in the physical world and the concepts developed to explain them - shows that science is a rational human endeavor with a long and continuing tradition, involving many different cultures and people - develops facility in critical thinking, reasoned argumentation, evaluation of evidence, mathematical modeling, and ethical values The treatment emphasizes not only what we know but also how we know it, why we believe it, and what effects that knowledge has - Why do we believe the Earth and planets revolve around the Sun? - Why do we believe that matter is made of atoms? - How do relativity theory and quantum mechanics alter our conception of Nature and in what ways do th...

  12. Electrophysiological evidence for the continuous processing of linguistic categories of regular and irregular verb inflection in German. (United States)

    Smolka, Eva; Khader, Patrick H; Wiese, Richard; Zwitserlood, Pienie; Rösler, Frank


    A central question concerning word recognition is whether linguistic categories are processed in continuous or categorical ways, in particular, whether regular and irregular inflection is stored and processed by the same or by distinct systems. Here, we contribute to this issue by contrasting regular (regular stem, regular suffix) with semi-irregular (regular stem, irregular suffix) and irregular (irregular stem, irregular suffix) participle formation in a visual priming experiment on German verb inflection. We measured ERPs and RTs and manipulated the inflectional and meaning relatedness between primes and targets. Inflected verb targets (e.g., leite, "head") were preceded either by themselves, by their participle (geleitet, "headed"), by a semantically related verb in the same inflection as the target (führe, "guide") or in the participle form (geführt, "guided"), or by an unrelated verb in the same inflection (nenne, "name"). Results showed that behavioral and ERP priming effects were gradually affected by verb regularity. Regular participles produced a widely distributed frontal and parietal effect, irregular participles produced a small left parietal effect, and semi-irregular participles yielded an effect in-between these two in terms of amplitude and topography. The behavioral and ERP effects further showed that the priming because of participles differs from that because of semantic associates for all verb types. These findings argue for a single processing system that generates participle priming effects for regular, semi-irregular, and irregular verb inflection. Together, the findings provide evidence that the linguistic categories of verb inflection are processed continuously. We present a single-system model that can adequately account for such graded effects.

  13. Turismo irregular


    Santiago Londoño Vélez


    Tesoros de Cartagena. Germán Téllez y Alfredo Iriarte. El Sello editores, Bogotá, 1991. Homenaje al Cauca. Varios autores. Villegas Editores, Bogotá, 1991. Por los caminos de Caldas. Batriz Zuluaga V. y Omar Morales B. Ediciones Hoge, Bogotá (?), 1991.

  14. Irregular incentives

    International Nuclear Information System (INIS)

    Cicchetti, M.A.


    Public utility regulation lacks a formal proxy for the economic profits that can be earned in an effectively competitive market if a firm is efficient or innovative. After all, public utility regulation operated on cost-plus basis. If a utility is efficient or innovative and lowers its costs, its typical reward is to have its rates reduced. This is a perverse incentive to motivate a utility to produce at the most efficient level. In addition, since regulation operates on this cost-plus basis, a utility can increase its net income, all other things being equal, by overinvesting in (or open-quotes gold-platingclose quotes) its system, another perverse incentive. Recognizing these flaws of regulation, academicians, utility executives, regulators, and legislators have tried over the last several years to implement incentive regulation plans that correct such perverse incentives. However, under many of the earnings-sharing or price-regulation incentive plans, the rewards for efficient production are not tied directly to measures under a company's control. In fact, such plans could prove highly detrimental to ratepayers and competitors of the regulated company and its affiliates. An incentive regulation plan that ties an appropriate reward for efficient production to specific efficiency gains is a better proxy of an effectively competitive environment. What's more, it is superior to an incentive plan that rewards circumstances beyond the company's control or self-serving manipulation. This is particularly true if no earnings cap is associated with the reward for efficiency. Rewards for efficient production should be tied to specific actions. A suitable incentive plan does not preclude appropriately derived flexible prices for certain products or services where warranted

  15. Ionospheric Irregularities Characterization by Ground and Space-based GPS Observations (United States)

    Zakharenkova, I.; Cherniak, I.; Krankowski, A.


    We present new results on detection and investigation of the topside ionospheric irregularities using GPS measurements from Precise Orbit Determination (POD) GPS antenna onboard Low Earth Orbit satellites. Our investigation is based on the recent ESA's Swarm mission launched on 22 November 2013 and consisted of three identical satellites, two of them fly in a tandem at an orbit altitude of 460 km while the third satellite - at an orbit altitude of 510 km. Each satellite is equipped with a zenith-looking antenna and 8-channel dual-frequency GPS receiver that delivered 1 Hz data for POD purposes, as well as Langmuir Probe instrument for in situ electron density. Additionally, we have analyzed GPS measurements onboard GRACE and TerraSAR-X satellite, which have rather similar to Swarm orbit altitude of 500 km. GPS measurements onboard MetOP-A and MetOP-B satellites (altitude of 840 km) can complement these observations in order to estimate an altitudinal extent of the ionospheric irregularities penetrating to higher altitudes. We demonstrate that space-based GPS observations can be effectively used for monitoring of the topside ionospheric irregularities occurrence in both high-latitude and equatorial regions and may essentially contribute to the multi-instrumental analysis of the ground-based and in situ data. Climatological characteristics of the equatorial ionospheric irregularities occurrence probability are derived from POD GPS measurements for all longitudinal sectors for the years 2013-2016. Several examples of strong geomagnetic storms, including the 2015 St. Patrick's Day storm, were analyzed to demonstrate differences between the climatlogical characteristics in space-based GPS data and storm-induced equatorial irregularities observations (postsunset suppression, night/morning-time occurrence). To support our observations and conclusions, we involve into our analysis in situ plasma density provided by Swarm constellation, GRACE KBR, DMSP satellites, as well


    International Nuclear Information System (INIS)

    Dowell, Jayce D.; Buckalew, Brent A.; Tan, Jonathan C.


    The initial cluster mass function (ICMF) is a fundamental property of star formation in galaxies. To gauge its universality, we measure and compare the ICMFs in irregular and spiral galaxies. Our sample of irregular galaxies is based on 13 nearby galaxies selected from a volume-limited sample from the fifth data release of the Sloan Digital Sky Survey (SDSS), from which about 320 young (≤20 Myr), massive (∼> 3 x 10 4 M sun ) clusters or associations were selected using an automated source extraction routine. The extinctions, ages, and masses were determined by comparing their u'g'i'z' magnitudes to those generated from starburst models. Completeness corrections were performed using Monte Carlo simulations in which artificial clusters were inserted into each galaxy. Foreground stellar and background galactic contaminations were assessed by analyzing SDSS images of fields around the sample galaxies and found to be small. We analyzed three nearby spiral galaxies with SDSS data exactly in the same way to derive their ICMF based on a similar number of young, massive clusters as the irregular galaxy ICMF. We find that the ICMFs of irregular and spiral galaxies for masses >10 4.4 M sun are statistically indistinguishable. For clusters and associations more massive than 10 4.4 M sun , the ICMF of the irregular galaxies is reasonably well fit by a power law dN(M)/dM∝M -α M with α M = 1.88 ± 0.09. Similar results were obtained for the ICMF of the spiral galaxy sample but with α M = 1.75 ± 0.06. We discuss the implications of our results on theories of star cluster formation, which appear to indicate that the power-law indices are independent of metallicity and galactic shear rate. We also examine the evolution of visual extinction, A V , with cluster age and find significant reduction in median extinction after ∼ 5-10 Myr by about 0.5 mag for clusters in both spiral and irregular galaxies. We discuss the implications of our results for theories of star cluster

  17. Simultaneous observations of ESF irregularities over Indian region using radar and GPS

    Directory of Open Access Journals (Sweden)

    S. Sripathi


    Full Text Available In this paper, we present simultaneous observations of temporal and spatial variability of total electron content (TEC and GPS amplitude scintillations on L1 frequency (1.575 GHz during the time of equatorial spread F (ESF while the MST radar (53 MHz located at Gadanki (13.5° N, 79.2° E, Dip latitude 6.3° N, a low latitude station, made simultaneous observations. In particular, the latitudinal and longitudinal extent of TEC and L-band scintillations was studied in the Indian region for different types of ESF structures observed using the MST radar during the low solar activity period of 2004 and 2005. Simultaneous radar and GPS observations during severe ESF events in the pre-midnight hour reveal that significant GPS L band scintillations, depletions in TEC, and the double derivative of the TEC index (DROTI, which is a measure of fluctuations in TEC, obtained at low latitudes coincide with the appearance of radar echoes at Gadanki. As expected, when the irregularities reach higher altitudes as seen in the radar map during pre-midnight periods, strong scintillations on an L-band signal are observed at higher latitudes. Conversely, when radar echoes are confined to only lower altitudes, weak scintillations are found and their latitudinal extent is small. During magnetically quiet periods, we have recorded plume type radar echoes during a post-midnight period that is devoid of L-band scintillations. Using spectral slopes and cross-correlation index of the VHF scintillation observations, we suggest that these irregularities could be "dead" or "fossil" bubbles which are just drifting in from west. This scenario is consistent with the observations where suppression of pre-reversal enhancement (PRE in the eastward electric field is indicated by ionosonde observations of the height of equatorial F layer and also occurrence of low spectral width in the radar observations relative to pre-midnight period. However, absence of L-band scintillations during

  18. The Withdrawal of Health Care from Irregular Immigrants and Medical Conscientious Objection

    Directory of Open Access Journals (Sweden)

    Yolanda Garcìa Ruiz


    Full Text Available The economic crisis so strongly affecting some southern European countries has led to significant cuts in the system of universal public health care in Spain. Such measures particularly affect irregular immigrants and can also cause significant public health consequences. A form of civil resistance that deserves to be analyzed is the conscientious objection of Spanish doctors who have chosen to continue attending irregular immigrants in contravention of new the rules restricting their access to the public health system and their right to health. The aim of this paper is to analyze the new regulation which cut health care for irregular immigrants in Spain, the impact of this new regulation on the most vulnerable groups, and the response of doctors, who exercised their right to conscientious objection in relation to applying the new regulation. Finally to examine the announcement of change which came about as a consequence of international and domestic social pressure causing political risk to the Spanish National Government. La crisis económica, que ha afectado tan profundamente a algunos países del sur de Europa, ha dado lugar a significativos recortes en el sistema de atención sanitaria pública en España. Algunas de las medidas adoptadas han afectado específicamente a los inmigrantes irregulares y pueden tener, incluso, efectos en el ámbito de la salud pública. Una forma de desobediencia civil que merece ser analizada es la declaración de objeción de conciencia de determinados médicos y profesionales sanitarios españoles que han continuado atendiendo a los inmigrantes irregulares en contra de las nuevas  restricciones impuestas por el Gobierno que afectan al reconocimiento universal del derecho a la salud. El propósito de este artículo es el de analizar la nueva regulación que limita el acceso a la asistencia sanitaria de los inmigrantes irregulares en España, el impacto de esta nueva regulación en los grupos más vulnerables

  19. The phase curve survey of the irregular saturnian satellites: A possible method of physical classification (United States)

    Bauer, James M.; Grav, Tommy; Buratti, Bonnie J.; Hicks, Michael D.


    During its 2005 January opposition, the saturnian system could be viewed at an unusually low phase angle. We surveyed a subset of Saturn's irregular satellites to obtain their true opposition magnitudes, or nearly so, down to phase angle values of 0.01°. Combining our data taken at the Palomar 200-inch and Cerro Tololo Inter-American Observatory's 4-m Blanco telescope with those in the literature, we present the first phase curves for nearly half the irregular satellites originally reported by Gladman et al. [2001. Nature 412, 163-166], including Paaliaq (SXX), Siarnaq (SXXIX), Tarvos (SXXI), Ijiraq (SXXII), Albiorix (SXVI), and additionally Phoebe's narrowest angle brightness measured to date. We find centaur-like steepness in the phase curves or opposition surges in most cases with the notable exception of three, Albiorix and Tarvos, which are suspected to be of similar origin based on dynamical arguments, and Siarnaq.

  20. Mei symmetry and conservation laws of discrete nonholonomic dynamical systems with regular and irregular lattices

    International Nuclear Information System (INIS)

    Zhao Gang-Ling; Chen Li-Qun; Fu Jing-Li; Hong Fang-Yu


    In this paper, Noether symmetry and Mei symmetry of discrete nonholonomic dynamical systems with regular and the irregular lattices are investigated. Firstly, the equations of motion of discrete nonholonomic systems are introduced for regular and irregular lattices. Secondly, for cases of the two lattices, based on the invariance of the Hamiltomian functional under the infinitesimal transformation of time and generalized coordinates, we present the quasi-extremal equation, the discrete analogues of Noether identity, Noether theorems, and the Noether conservation laws of the systems. Thirdly, in cases of the two lattices, we study the Mei symmetry in which we give the discrete analogues of the criterion, the theorem, and the conservative laws of Mei symmetry for the systems. Finally, an example is discussed for the application of the results

  1. Prevalence of irregular red blood cell antibodies among healthy blood donors in Delhi population. (United States)

    Garg, Neeraj; Sharma, Tanya; Singh, Bharat


    To evaluate the prevalence of the anti-red blood cell antibodies among healthy blood donors. Antibody screening of all voluntary blood donor serum was performed as routine immunohematological procedure. Positive sera were further investigated to identify the specificity of irregular erythrocyte antibody by commercially available red cell panel (ID-Dia Panel, Diamed-ID Microtyping System). A total of 47,450 donors were screened for the presence of irregular erythrocyte antibodies. A total of forty-six donors showed presence of alloantibodies in their serum (46/47,450%, 0.09%), yielding a prevalence of 0.09%. Most frequent alloantibodies identified were of MNS blood group system. The results showed statistically a higher prevalence of RBC alloantibodies in females than in males. Screening for presence of alloantibodies in donor blood is important to provide compatible blood products and to avoid transfusion reactions. Copyright © 2014 Elsevier Ltd. All rights reserved.

  2. Radiative heat transfer for irregular geometries with the collapsed dimension method

    Energy Technology Data Exchange (ETDEWEB)

    Talukdar, Prabal [Institute of Fluid Mechanics, University of Erlangen-Nuremberg, Cauerstrasse 4, 91058 Erlangen (Germany)


    A blocked-off region procedure is implemented with the collapsed dimension method (CDM) to deal with radiative transport problems in irregular geometries. Different test problems are validated for radiative and non-radiative equilibrium situations in participating or non-participating media. Results are found to be satisfactory for all straight edged, inclined and curved boundaries. The blocked-off region procedure based on Cartesian coordinate is found to be very convenient for a ray-tracing method like the CDM. The same ray tracing algorithm for a rectangular enclosure could be effectively used for any kind of 2-D geometries. This significantly reduces the effort of developing different ray-tracing algorithm for different geometries. In addition, it is an alternative than to write an algorithm in curvilinear coordinate for irregular geometries which found to be complicated for a ray-tracing method like the CDM. (author)

  3. CORPORATE GOVERNANCE AND ACCOUNTING IRREGULARITIES: Evidence from the Two-tiered Board Structure in Indonesia

    Directory of Open Access Journals (Sweden)

    Jaswadi JASWADI


    Full Text Available This study aims to investigate the extent to which the Indonesian corporate governance mechanism acts as an effective tool for protecting financial statements users against accounting irregularities. Considering that accounting irregularities might occur in between error and the fraud act, this study reviews the literature on minimizing the seriousness of these reporting incidences. The level of seriousness in misstatements is more severe when: (1 there is absence of financial expert(s on supervisory boards and audit committees, (2 companies have short tenured-CEOs and poor internal control systems, and (3 auditors are solely appointed by firms’ BOCs without agreement of block holders (known as referral. In addition, an examination of simultaneous effects of each corporate governance dimension reveals a general weakness of the BOCs and their audit committees. However, the BOC and audit committee could be an effective tool in mitigating reporting incidences, especially when they show high-quality collaboration.

  4. Provision of health services to irregular migrants with a special focus on children. (United States)

    Søvig, Karl Harald


    All European countries are now facing a situation where a part of the population consists of migrants without a permit to stay or reside. These persons may have health problems, and the question then rises regarding health services to irregular migrants. Normally, welfare benefits are offered those with a relationship to the country concerned, as citizen, asylum seeker, tourist, etc. Irregular migrants are outside the society, and it could be suggested that they therefore should be denied health services. On the other hand, common European standards of humanity lay obligations on the States, for example, where situations are life-threatening. This contribution gives an overview of relevant legal instruments, both from the UN, Council of Europe and the European Union. Although there are many similarities, the instruments have their differences, and there may even be some tensions regarding the underlying values.

  5. Time-Scale and Time-Frequency Analyses of Irregularly Sampled Astronomical Time Series

    Directory of Open Access Journals (Sweden)

    S. Roques


    Full Text Available We evaluate the quality of spectral restoration in the case of irregular sampled signals in astronomy. We study in details a time-scale method leading to a global wavelet spectrum comparable to the Fourier period, and a time-frequency matching pursuit allowing us to identify the frequencies and to control the error propagation. In both cases, the signals are first resampled with a linear interpolation. Both results are compared with those obtained using Lomb's periodogram and using the weighted waveletZ-transform developed in astronomy for unevenly sampled variable stars observations. These approaches are applied to simulations and to light variations of four variable stars. This leads to the conclusion that the matching pursuit is more efficient for recovering the spectral contents of a pulsating star, even with a preliminary resampling. In particular, the results are almost independent of the quality of the initial irregular sampling.

  6. A new inequality for the Riemann-Stieltjes integrals driven by irregular signals in Banach spaces. (United States)

    Łochowski, Rafał M


    We prove an inequality of the Loéve-Young type for the Riemann-Stieltjes integrals driven by irregular signals attaining their values in Banach spaces, and, as a result, we derive a new theorem on the existence of the Riemann-Stieltjes integrals driven by such signals. Also, for any [Formula: see text], we introduce the space of regulated signals [Formula: see text] ([Formula: see text] are real numbers, and W is a Banach space) that may be uniformly approximated with accuracy [Formula: see text] by signals whose total variation is of order [Formula: see text] as [Formula: see text] and prove that they satisfy the assumptions of the theorem. Finally, we derive more exact, rate-independent characterisations of the irregularity of the integrals driven by such signals.

  7. Pathways to clinical CLARITY: volumetric analysis of irregular, soft, and heterogeneous tissues in development and disease. (United States)

    Hsueh, Brian; Burns, Vanessa M; Pauerstein, Philip; Holzem, Katherine; Ye, Li; Engberg, Kristin; Wang, Ai-Chi; Gu, Xueying; Chakravarthy, Harini; Arda, H Efsun; Charville, Gregory; Vogel, Hannes; Efimov, Igor R; Kim, Seung; Deisseroth, Karl


    Three-dimensional tissue-structural relationships are not well captured by typical thin-section histology, posing challenges for the study of tissue physiology and pathology. Moreover, while recent progress has been made with intact methods for clearing, labeling, and imaging whole organs such as the mature brain, these approaches are generally unsuitable for soft, irregular, and heterogeneous tissues that account for the vast majority of clinical samples and biopsies. Here we develop a biphasic hydrogel methodology, which along with automated analysis, provides for high-throughput quantitative volumetric interrogation of spatially-irregular and friable tissue structures. We validate and apply this approach in the examination of a variety of developing and diseased tissues, with specific focus on the dynamics of normal and pathological pancreatic innervation and development, including in clinical samples. Quantitative advantages of the intact-tissue approach were demonstrated compared to conventional thin-section histology, pointing to broad applications in both research and clinical settings.

  8. Placement effect on the stability of tetrapod armor unit on breakwaters in irregular waves (United States)

    Çelikoğlu, Yeşim; Engin, Demet


    Tetrapod, one of the well-known artificial concrete units, is frequently used as an armor unit on breakwaters. Two layers of tetrapod units are normmaly placed on the breakwaters with different placement methods. In this study, the stability of tetrapod units with two different regularly placement methods are investigated experimentally in irregular waves. Stability coefficients of tetrapod units for both placement methods are obtained. The important characteristic wave parameters of irregular waves causing the same damage ratio as those of the regular waves are also determined. It reveals that the average of one-tenth highest wave heights within the wave train ( H 1/10) causes the similar damage as regular waves.

  9. Identifying irregularly shaped crime hot-spots using a multiobjective evolutionary algorithm (United States)

    Wu, Xiaolan; Grubesic, Tony H.


    Spatial cluster detection techniques are widely used in criminology, geography, epidemiology, and other fields. In particular, spatial scan statistics are popular and efficient techniques for detecting areas of elevated crime or disease events. The majority of spatial scan approaches attempt to delineate geographic zones by evaluating the significance of clusters using likelihood ratio statistics tested with the Poisson distribution. While this can be effective, many scan statistics give preference to circular clusters, diminishing their ability to identify elongated and/or irregular shaped clusters. Although adjusting the shape of the scan window can mitigate some of these problems, both the significance of irregular clusters and their spatial structure must be accounted for in a meaningful way. This paper utilizes a multiobjective evolutionary algorithm to find clusters with maximum significance while quantitatively tracking their geographic structure. Crime data for the city of Cincinnati are utilized to demonstrate the advantages of the new approach and highlight its benefits versus more traditional scan statistics.

  10. Irregular Polyomino-Shaped Subarrays for Space-Based Active Arrays

    Directory of Open Access Journals (Sweden)

    R. J. Mailloux


    Full Text Available This paper presents new results showing the application of polyomino-based subarrays to limited field of view and wideband, wide-angle scanning. This technology can reduce the number of phase controls in arrays used for limited sector coverage or the number of time delay devices for wideband radar or communications, and so can reduce the cost of space-based active arrays. We concentrate on the wideband application. Results are presented by comparing the gain and peak sidelobe results of irregular polyomino subarray-based arrays with those of rectangular subarrays. It is shown that using irregular polyomino subarrays can result in a major decrease in sidelobes while presenting, in most cases, only a few tenths of a dB gain reduction compared to rectangular subarrays.

  11. Artificial periodic irregularities in the high-latitude ionosphere excited by the HAARP facility (United States)

    Bakhmetieva, N. V.; Grach, S. M.; Sergeev, E. N.; Shindin, A. V.; Milikh, G. M.; Siefring, C. L.; Bernhardt, P. A.; McCarrick, M.


    We present results of the new observations of artificial periodic irregularities (APIs) in the ionosphere using the High Frequency Active Auroral Research Program (HAARP) heating facility carried out in late May and early June 2014.The objective of this work is to detect API using high-latitude facility and analyze possible differences of the temporal and spatial variations of the API echoes in the high (HAARP) and middle (Sura) latitudes. Irregularities were created by the powerful wave of X mode and were sounded using the short probing pulses signals of X mode. API echoes were observed in the D, E, and F regions of the ionosphere. Amplitudes and characteristic times of the API echoes were measured. The API growth and decay times at HAARP (high latitudes) observed were similar to those at the Sura heating facility (midlatitudes).

  12. An Efficient Heuristic Approach for Irregular Cutting Stock Problem in Ship Building Industry

    Directory of Open Access Journals (Sweden)

    Yan-xin Xu


    Full Text Available This paper presents an efficient approach for solving a real two-dimensional irregular cutting stock problem in ship building industry. Cutting stock problem is a common cutting and packing problem that arises in a variety of industrial applications. A modification of selection heuristic Exact Fit is applied in our research. In the case referring to irregular shapes, a placement heuristics is more important to construct a complete solution. A placement heuristic relating to bottom-left-fill is presented. We evaluate the proposed approach using generated instance only with convex shapes in literatures and some instances with nonconvex shapes based on real problem from ship building industry. The results demonstrate that the effectiveness and efficiency of the proposed approach are significantly better than some conventional heuristics.

  13. Comments on modeling the sound fields in an irregular ocean by causal first-order equations (United States)

    Gulin, O. É.


    Two comments on using the causal matrix equations derived earlier for modeling the sound fields in a horizontally irregular medium are presented. The comments should be taken into account in practical calculations. The first of them is concerned with the discontinuities in the parameters of the medium along the propagation path. To eliminate the problems arising in this case, the mode evolution equations are modified to the case of matched boundaries of the irregular region and the layered part of the medium. The second comment refines the description of the specific case of a two-dimensionally inhomogeneous medium with the azimuthal symmetry in the horizontal plane. To reformulate the boundary-value problem to the problem for equations with initial conditions, the consideration of the more general three-dimensional initial problem with an azimuth angle is proposed with the sound source positioned at an arbitrary distance from the origin of coordinates.

  14. Coiled-Coil Irregularities and Instabilities in Group A Streptococcus M1 Are Required for Virulence

    Energy Technology Data Exchange (ETDEWEB)

    McNamara, Case; Zinkernagel, Annelies S.; Macheboeuf, Pauline; Cunningham, Madeleine W.; Nizet, Victor; Ghosh, Partho (UO-HSC); (UCSD)


    Antigenically variable M proteins are major virulence factors and immunogens of the human pathogen group A Streptococcus (GAS). Here, we report the -3 angstrom resolution structure of a GAS M1 fragment containing the regions responsible for eliciting type-specific, protective immunity and for binding fibrinogen, which promotes M1 proinflammatory and antiphagocytic functions. The structure revealed substantial irregularities and instabilities throughout the coiled coil of the M1 fragment. Similar structural irregularities occur in myosin and tropomyosin, explaining the patterns of cross-reactivity seen in autoimmune sequelae of GAS infection. Sequence idealization of a large segment of the M1 coiled coil enhanced stability but diminished fibrinogen binding, proinflammatory effects, and antibody cross-reactivity, whereas it left protective immunogenicity undiminished. Idealized M proteins appear to have promise as vaccine immunogens.

  15. An experimental study of irregular wave forces on multiple quasi-ellipse caissons (United States)

    Ren, Xiaozhong; Zhang, Peng; Ma, Yuxiang; Meng, Yufan


    An experimental investigation of irregular wave forces on quasi-ellipse caisson structures is presented. Irregular waves were generated based on the Jonswap spectrum with two significant wave heights, and the spectrum peak periods range from 1.19 s to 1.81 s. Incident wave directions relative to the centre line of the multiple caissons are from 0° to 22.5°. The spacing between caissons ranges from 2 to 3 times that of the width of the caisson. The effects of these parameters on the wave forces of both the perforated and non-perforated caissons were compared and analyzed. It was found that the perforated caisson can reduce wave forces, especially in the transverse direction. Furthermore, the relative interval and incident wave direction have significant effects on the wave forces in the case of multiple caissons.

  16. Irregular Firing and High-Conductance States in Spinal Motoneurons during Scratching and Swimming

    DEFF Research Database (Denmark)

    Guzulaitis, Robertas; Hounsgaard, Jorn; Alaburda, Aidas


    UNLABELLED: Intense synaptic transmission during scratch network activity increases conductance and induces irregular firing in spinal motoneurons. It is not known whether this high-conductance state is a select feature for scratching or a property that goes with spinal motor network activity...... in general. Here we compare conductance and firing patterns in spinal motoneurons during network activity for scratching and swimming in an ex vivo carapace-spinal cord preparation from adult turtles (Trachemys scripta elegans). The pattern and relative engagement of motoneurons are distinctly different...... in scratching and swimming. Nevertheless, we found increased synaptic fluctuations in membrane potential, irregular firing, and increased conductance in spinal motoneurons during scratch and swim network activity. Our finding indicates that intense synaptic activation of motoneurons is a general feature...

  17. Serbian migration policy concerning irregular migration and asylum in the context of the EU integration process

    Directory of Open Access Journals (Sweden)

    Marta Stojić-Mitrović


    Full Text Available In this paper I would like to present Serbian migration policy concerning irregular migration and asylum in the context of the attempts of the Serbian state to become a member of the European Union. I would describe the history of the asylum system prior and after the implementation of the independent asylum system in Serbia in 2008. My presentation of the Serbian migration policy would be channelled by the analysis of some particular political issues, such as the externalization of the EU borders’ control, as well as some relevant elements of the European integration process, like visa liberalization. The second, more culturally specific dimension of the issue would be accessed through the demonstration of both legislative and public conceptualizations of the irregular migrants, asylum seekers and refugees in Serbia.

  18. Tremor Irregularity, Torque Steadiness and Rate of Force Development in Parkinson's Disease

    DEFF Research Database (Denmark)

    Rose, Martin Høyer; Løkkegaard, Annemette; Sonne-Holm, Stig


    We investigated lower-extremity isometric tremor Approximate Entropy (irregularity), torque steadiness and rate of force development (RFD) and their associations to muscle activation strategy during isometric knee extensions in patients with Parkinson's disease (PD). Thirteen male patients...... that both knee isometric tremor Approximate Entropy and torque steadiness clearly differentiate between patients with PD and healthy controls. Furthermore, severely compromised RFD was found in patients with PD and was associated with decreased agonist muscle activation....... with idiopathic PD and 15 neurologically healthy matched controls performed isometric maximal contractions (extension/flexion) as well as steady submaximal and powerful isometric knee extensions. The patients with PD showed decreased isometric tremor irregularity. Torque steadiness was reduced in PD...

  19. Isometric Tremor Irregularity, Torque Steadiness and Rate of Force Development in Parkinson's Disease

    DEFF Research Database (Denmark)

    Rose, Martin Høyer; Løkkegaard, Annemette; Sonne-Holm, Stig


    We investigated lower-extremity isometric tremor Approximate Entropy (irregularity), torque steadiness and rate of force development (RFD) and their associations to muscle activation strategy during isometric knee extensions in patients with Parkinson's disease (PD). Thirteen male patients...... that both knee isometric tremor Approximate Entropy and torque steadiness clearly differentiate between patients with PD and healthy controls. Furthermore, severely compromised RFD was found in patients with PD and was associated with decreased agonist muscle activation....... with idiopathic PD and 15 neurologically healthy matched controls performed isometric maximal contractions (extension/flexion) as well as steady submaximal and powerful isometric knee extensions. The patients with PD showed decreased isometric tremor irregularity. Torque steadiness was reduced in PD...

  20. Tremor irregularity, torque steadiness and rate of force development in Parkinson's disease

    DEFF Research Database (Denmark)

    Rose, Martin Høyer; Løkkegaard, Annemette; Sonne-Holm, Stig


    We investigated lower-extremity isometric tremor Approximate Entropy (irregularity), torque steadiness and rate of force development (RFD) and their associations to muscle activation strategy during isometric knee extensions in patients with Parkinson's disease (PD). Thirteen male patients...... that both knee isometric tremor Approximate Entropy and torque steadiness clearly differentiate between patients with PD and healthy controls. Furthermore, severely compromised RFD was found in patients with PD and was associated with decreased agonist muscle activation....... with idiopathic PD and 15 neurologically healthy matched controls performed isometric maximal contractions (extension/flexion) as well as steady submaximal and powerful isometric knee extensions. The patients with PD showed decreased isometric tremor irregularity. Torque steadiness was reduced in PD...

  1. Penalized likelihood and multi-objective spatial scans for the detection and inference of irregular clusters. (United States)

    Cançado, André L F; Duarte, Anderson R; Duczmal, Luiz H; Ferreira, Sabino J; Fonseca, Carlos M; Gontijo, Eliane C D M


    Irregularly shaped spatial clusters are difficult to delineate. A cluster found by an algorithm often spreads through large portions of the map, impacting its geographical meaning. Penalized likelihood methods for Kulldorff's spatial scan statistics have been used to control the excessive freedom of the shape of clusters. Penalty functions based on cluster geometry and non-connectivity have been proposed recently. Another approach involves the use of a multi-objective algorithm to maximize two objectives: the spatial scan statistics and the geometric penalty function. We present a novel scan statistic algorithm employing a function based on the graph topology to penalize the presence of under-populated disconnection nodes in candidate clusters, the disconnection nodes cohesion function. A disconnection node is defined as a region within a cluster, such that its removal disconnects the cluster. By applying this function, the most geographically meaningful clusters are sifted through the immense set of possible irregularly shaped candidate cluster solutions. To evaluate the statistical significance of solutions for multi-objective scans, a statistical approach based on the concept of attainment function is used. In this paper we compared different penalized likelihoods employing the geometric and non-connectivity regularity functions and the novel disconnection nodes cohesion function. We also build multi-objective scans using those three functions and compare them with the previous penalized likelihood scans. An application is presented using comprehensive state-wide data for Chagas' disease in puerperal women in Minas Gerais state, Brazil. We show that, compared to the other single-objective algorithms, multi-objective scans present better performance, regarding power, sensitivity and positive predicted value. The multi-objective non-connectivity scan is faster and better suited for the detection of moderately irregularly shaped clusters. The multi

  2. [Micro-column gel indirect anti-globulin technique for screening and identification of irregular antibody]. (United States)

    Ma, Shu-Xuan; Liu, Jing-Han; Li, Xi-Jin; Luo, Qun; Chen, Min-Cai; Wang, Hai-Jun


    The purpose of this study was to design an antibody screening method based on the micro-column gel indirect anti-globulin technique (MGIAT), using pooled cells and plasma, by comparison with the conventional indirect anti-globulin technique (CIAT) combined with a two-stage papain technique, and to explore the feasibility of the use of plasma instead of serum as test material. The samples of blood recipients in our hospital were screened for irregular antibody using pooled test cells. Screening of the antibodies was identified both by MGIAT and CIAT combined papain technique respectively. The results showed that the irregular erythrocyte antibodies were detected in 20 cases from 5,000 recipients screened by MGIAT, using pooled cells, the positive rate was 0.4%. The specificity of 20 cases of irregular antibodies was as follows: 2 cases of anti-D, 8 cases of anti-E, 1 cases of anti-C, 2 cases of anti-c, 2 cases of anti-Mi(a), 2 cases of anti-Jk(a), 1 case of anti-Le(a) and 2 cases of anti-Fy(a). Antibody was detected from 19 cases using CIAT. Anti-Le(a) was detected with adding complement from Le(a-b-) person. Only 13 cases antibody were found by papain technique. It was concluded that irregular antibody screening by MGIAT using pooled cells can take place of the CIAT combining with papain technique in clinical application. Plasma is superior to serum in antibody screening test.

  3. Generalized Simplified Variable-Scaled Min Sum LDPC decoder for irregular LDPC Codes


    Emran, Ahmed A.; Elsabrouty, Maha


    In this paper, we propose a novel low complexity scaling strategy of min-sum decoding algorithm for irregular LDPC codes. In the proposed method, we generalize our previously proposed simplified Variable Scaled Min-Sum (SVS-min-sum) by replacing the sub-optimal starting value and heuristic update for the scaling factor sequence by optimized values. Density evolution and Nelder-Mead optimization are used offline, prior to the decoding, to obtain the optimal starting point and per iteration upd...

  4. General Lines of Disregard for the Legal Personality on Irregular Dissolution the Company


    Fábio Augusto Barcelos Moreira Corrêa; Tereza Cristina Monteiro Mafra


    This article will analyze the Institute of disregard for the legal personality in situations involving irregular dissolution the limited liability company, in light of the jurisprudence of the Superior Court Tribunal. We highlight the impact that new code of Civil procedure will provide for analysis to safeguard the autonomy of assets of the legal person, as well as the guarantee of due process and of ample defense, directly impacting on business law. The analysis aims to contribute to the un...

  5. Fickle Allies: Regular and Irregular Confederate Forces in Missouri during the American Civil War (United States)


    experiences of Civil War Missouri. Three such accounts are Thomas Snead’s The Fight for Missouri: From the Election of Lincoln to the Death of Lyon...role of irregular forces in modern warfare. As a means of roadmap, the monograph begins with an orientation to the strategic context and operational...incredible advantage to either side.22 21Paul C. Nagel , Missouri, a History (Lawrence, KS: University Press of Kansas, 1977), 130-132. 22David Nevin

  6. Puncturing the Counterinsurgency Myth: Britain and Irregular Warfare in the Past, Present, and Future (United States)


    FUTURE INTRODUCTION Britain’s irregular warfare experience in the post- World War II era presented the military with numer- ous insurgent challenges where...STRATEGICALLY PERCEPTIVE This myth points to a painful element of British COIN conduct, namely, the short -circuiting of con- text. The preference for...military to plan for long-term coalition commitments: “Increasing globalisation ties our security to that of our allies. . . . Therefore we must

  7. An Approach to Making SPAI and PSAI Preconditioning Effective for Large Irregular Sparse Linear Systems


    Jia, Zhongxiao; Zhang, Qian


    We investigate the SPAI and PSAI preconditioning procedures and shed light on two important features of them: (i) For the large linear system $Ax=b$ with $A$ irregular sparse, i.e., with $A$ having $s$ relatively dense columns, SPAI may be very costly to implement, and the resulting sparse approximate inverses may be ineffective for preconditioning. PSAI can be effective for preconditioning but may require excessive storage and be unacceptably time consuming; (ii) the situation is improved dr...

  8. Penalized likelihood and multi-objective spatial scans for the detection and inference of irregular clusters

    Directory of Open Access Journals (Sweden)

    Fonseca Carlos M


    Full Text Available Abstract Background Irregularly shaped spatial clusters are difficult to delineate. A cluster found by an algorithm often spreads through large portions of the map, impacting its geographical meaning. Penalized likelihood methods for Kulldorff's spatial scan statistics have been used to control the excessive freedom of the shape of clusters. Penalty functions based on cluster geometry and non-connectivity have been proposed recently. Another approach involves the use of a multi-objective algorithm to maximize two objectives: the spatial scan statistics and the geometric penalty function. Results & Discussion We present a novel scan statistic algorithm employing a function based on the graph topology to penalize the presence of under-populated disconnection nodes in candidate clusters, the disconnection nodes cohesion function. A disconnection node is defined as a region within a cluster, such that its removal disconnects the cluster. By applying this function, the most geographically meaningful clusters are sifted through the immense set of possible irregularly shaped candidate cluster solutions. To evaluate the statistical significance of solutions for multi-objective scans, a statistical approach based on the concept of attainment function is used. In this paper we compared different penalized likelihoods employing the geometric and non-connectivity regularity functions and the novel disconnection nodes cohesion function. We also build multi-objective scans using those three functions and compare them with the previous penalized likelihood scans. An application is presented using comprehensive state-wide data for Chagas' disease in puerperal women in Minas Gerais state, Brazil. Conclusions We show that, compared to the other single-objective algorithms, multi-objective scans present better performance, regarding power, sensitivity and positive predicted value. The multi-objective non-connectivity scan is faster and better suited for the

  9. The U.S. Navy’s Vision for Confronting Irregular Challenges (United States)


    AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Chief of Naval Operations...Washington,DC,20301 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) 11...stabilize regions at risk, and when necessary, dissuade, deter, and defeat irregUlar actors who seek to undermine security, stability, and prosperity

  10. Increased Firing Irregularity as an Emergent Property of Neural-State Transition in Monkey Prefrontal Cortex (United States)

    Sakamoto, Kazuhiro; Katori, Yuichi; Saito, Naohiro; Yoshida, Shun; Aihara, Kazuyuki; Mushiake, Hajime


    Flexible behaviors are organized by complex neural networks in the prefrontal cortex. Recent studies have suggested that such networks exhibit multiple dynamical states, and can switch rapidly from one state to another. In many complex systems such as the brain, the early-warning signals that may predict whether a critical threshold for state transitions is approaching are extremely difficult to detect. We hypothesized that increases in firing irregularity are a crucial measure for predicting state transitions in the underlying neuronal circuits of the prefrontal cortex. We used both experimental and theoretical approaches to test this hypothesis. Experimentally, we analyzed activities of neurons in the prefrontal cortex while monkeys performed a maze task that required them to perform actions to reach a goal. We observed increased firing irregularity before the activity changed to encode goal-to-action information. Theoretically, we constructed theoretical generic neural networks and demonstrated that changes in neuronal gain on functional connectivity resulted in a loss of stability and an altered state of the networks, accompanied by increased firing irregularity. These results suggest that assessing the temporal pattern of neuronal fluctuations provides important clues regarding the state stability of the prefrontal network. We also introduce a novel scheme that the prefrontal cortex functions in a metastable state near the critical point of bifurcation. According to this scheme, firing irregularity in the prefrontal cortex indicates that the system is about to change its state and the flow of information in a flexible manner, which is essential for executive functions. This metastable and/or critical dynamical state of the prefrontal cortex may account for distractibility and loss of flexibility in the prefrontal cortex in major mental illnesses such as schizophrenia. PMID:24349020

  11. Irregular Meal Timing Is Associated with Helicobacter pylori Infection and Gastritis


    Lim, Su-Lin; Canavarro, Claudia; Zaw, Min-Htet; Zhu, Feng; Loke, Wai-Chiong; Chan, Yiong-Huak; Yeoh, Khay-Guan


    Helicobacter pylori (HP) is associated with chronic gastritis and gastric cancer, and more than half of the world's population is chronically infected. The aim of this retrospective study was to investigate whether an irregular meal pattern is associated with increased risk of gastritis and HP infection. The study involved 323 subjects, divided into three groups as follows: subjects with HP infection and gastritis, subjects with gastritis, and a control group. Subjects were interviewed on eat...

  12. A new galactic chemical evolution model with dust: results for dwarf irregular galaxies and DLA systems (United States)

    Gioannini, L.; Matteucci, F.; Vladilo, G.; Calura, F.


    We present a galactic chemical evolution model which adopts updated prescriptions for all the main processes governing the dust cycle. We follow in detail the evolution of the abundances of several chemical species (C, O, S, Si, Fe and Zn) in the gas and dust of a typical dwarf irregular galaxy. The dwarf irregular galaxy is assumed to evolve with a low but continuous level of star formation and experience galactic winds triggered by supernova (SN) explosions. We predict the evolution of the gas to dust ratio in such a galaxy and discuss critically the main processes involving dust, such as dust production by asymptotic giant branch stars and Type II SNe, destruction and accretion (gas condensation in clouds). We then apply our model to damped Lyman α (DLA) systems which are believed to be dwarf irregulars, as witnessed by their abundance patterns. Our main conclusions are the following. (I) We can reproduce the observed gas to dust ratio in dwarf galaxies. (II) We find that the process of dust accretion plays a fundamental role in the evolution of dust and in certain cases it becomes the dominant process in the dust cycle. On the other hand, dust destruction seems to be a negligible process in irregulars. (III) Concerning DLA systems, we show that the observed gas-phase abundances of silicon, normalized to volatile elements (zinc and sulfur), are in agreement with our model. (IV) The abundances of iron and silicon in DLA systems suggest that the two elements undergo a different history of dust formation and evolution. Our work casts light on the nature of iron-rich dust: the observed depletion pattern of iron is well reproduced only when an additional source of iron dust is considered. Here we explore the possibility of a contribution from Type Ia SNe as well as an efficient accretion of iron nanoparticles.

  13. Understanding PISA

    Directory of Open Access Journals (Sweden)

    Stephen DOWNES


    Full Text Available Understanding PISA Stephen DOWNESMoncton, CANADA ABSTRACT The headline was dramatic enough to cause a ripple in the reading public. "Students who use computers a lot at school have worse maths and reading performance," noted the BBC news article, citing a 2004 study by Ludger Woessmann and Thomas Fuchs (Fuchs and Woessman, 2004. It was not long before the blogosphere took notice. Taking the theme and running with it, Alice and Bill ask, "Computers Make School Kids Dumber?" They theorize, "If you track the admitted decline of education, you'll probably notice that it follows along with the increase of technology in the classroom." In a similar vein, James Bartholomew asks, "Do you think that the government will turn down the volume of its boasting about how it has spent billions introducing computers in schools (while keeping down the pay of teachers so much that there are shortages? Do you think it will stop sending governors of state schools glossy pamphlets about insisting that computers are used in their schools as much as possible?" In this study, therefore, PISA looks well beyond educational attainment, and also includes school demographics, such as whether it is a public or private school, has large or small classes, or has access or not to technological resources. Finally, it does measure student information-their family background, access to books and computers and parental support as well. The PISA survey departs from previous surveys in disregarding the stated curricula of the schools being measured. Therefore, the conclusion is not surprising, nor even wrong for him to consider independently of any parental or teacher support, considered without reference to the software running on it, considered without reference to student attitudes and interests, does not positively impact an education. Finally, he focus on missing the reporting of results

  14. Prognostic value of screening for irregular antibodies late in pregnancy in rhesus positive women. (United States)

    Andersen, Anita S; Praetorius, Lisbeth; Jørgensen, Henrik L; Lylloff, Kirsten; Larsen, Kim T


    To evaluate the prognostic value of screening for irregular antibodies late in pregnancy (third trimester) in rhesus positive women. Only those cases where irregular antibodies have not previously been demonstrated during routine screening in the first trimester with regard to clinically relevant complications in the newborn, were studied. All women living in Frederiksborg county and giving birth in 1996 (n = 4216) were assessed for inclusion in the study. This was done by gathering the files at the Hillerød and Hørsholm Hospitals' blood banks for antibody test results. Six hundred women were excluded because of the lack of either the rhesus type or the late antibody test. Of the 3616 women, 3046 were rhesus positive, and 3012 of these had a negative first trimester screen test. Fifteen of the 3012 women later developed irregular antibodies in the third trimester, and were included in the study. This corresponds to only 0.5%, and none of these cases entailed perinatal complications for the mother or the child. Routine screening of rhesus positive pregnant women in the third trimester is not rational from a cost-benefit perspective, if the only purpose is to prevent hemolytic disease of the newborn.

  15. Gel-test: interpretation and value of a new technique for the detection of irregular antibodies. (United States)

    Pottier, C; Quillet, P; Baufine-Ducrocq, H


    Here we report on our experience with the use of a 'Gel-Test' (DiaMed-ID Micro Typing System) technique for the detection and identification of irregular antibodies in a general hospital. This easy-to-use, standardized technique poses the question of the impact of its sensitivity on the specificity of the results. Of the 10% of observed positive reactions, 3.7% were irregular antibodies, 3.8% papain auto-antibodies, 1% cold antibodies and 2% not elucidated. Two hundred and eighteen irregular antibodies identified and titred with the 'gel-test' system were tested in parallel by 'tube' method. Sixty-three of these antibodies (29%) were not detected by the 'tube' method. While anti-Kell was always detected by both methods, we found the following false natives with the tube method: 15% anti-D, 32% anti-E, 42% anti-Cw and 58% anti-Lea. 68% of these false negatives had a low titre. The immunoglobulin class of the anti-E was studied; the sensitivity of the 'gel-test' system was associated with IgM in the anti-E. The sensitivity and standardization of the 'gel-test' technique guarantee greater safety in blood transfusion and increase efficiency in the prevention of foeto-maternal stimulation of anti-D.

  16. Electromagnetic waves in irregular multilayered spheroidal structures of finite conductivity: full wave solutions

    International Nuclear Information System (INIS)

    Bahar, E.


    The propagation of electromagnetic waves excited by electric dipoles oriented along the axis of multilayered spheroidal structures of finite conductivity is investigated. The electromagnetic parameters and the thickness of the layers of the structure are assumed to be functions of the latitude. In the analysis, electric and magnetic field transforms that constitute a discrete and a continuous spectrum of spherical waves are used to provide a suitable basis for the expansion of the electromagnetic fields at any point in the irregular spheroidal structure. For spheroidal structures with good conducting cores, the terms in the solutions associated with the continuous part of the wave spectrum vanish. In general, however, when the skin depth for the core is large compared to its dimensions or when the sources are located in the core of the structure and propagation in the core is of special interest, the contribution from the continuous part of the wave spectrum cannot be neglected. At each interface between the layers of the irregular spheroidal structure, exact boundary conditions are imposed. Since the terms of the field expansions in the irregular structure do not individually satisfy the boundary conditions, Maxwell's equations are reduced to sets of coupled ordinary first-order differential equations for the wave amplitudes. The solutions are shown to satisfy the reciprocity relationships in electromagnetic theory. The analysis may be applied to problems of radio wave propagation in a nonuniform model of the earth-ionosphere waveguide, particularly when focusing effects at the antipodes are important

  17. Surface Irregularity Factor as a Parameter to Evaluate the Fatigue Damage State of CFRP

    Directory of Open Access Journals (Sweden)

    Pablo Zuluaga-Ramírez


    Full Text Available This work presents an optical non-contact technique to evaluate the fatigue damage state of CFRP structures measuring the irregularity factor of the surface. This factor includes information about surface topology and can be measured easily on field, by techniques such as optical perfilometers. The surface irregularity factor has been correlated with stiffness degradation, which is a well-accepted parameter for the evaluation of the fatigue damage state of composite materials. Constant amplitude fatigue loads (CAL and realistic variable amplitude loads (VAL, representative of real in- flight conditions, have been applied to “dog bone” shaped tensile specimens. It has been shown that the measurement of the surface irregularity parameters can be applied to evaluate the damage state of a structure, and that it is independent of the type of fatigue load that has caused the damage. As a result, this measurement technique is applicable for a wide range of inspections of composite material structures, from pressurized tanks with constant amplitude loads, to variable amplitude loaded aeronautical structures such as wings and empennages, up to automotive and other industrial applications.

  18. Incidence of irregular astigmatism eligible for contact lens fitting after Descemet membrane endothelial keratoplasty. (United States)

    van Dijk, Korine; Parker, Jack; Liarakos, Vasilios S; Ham, Lisanne; Frank, Laurence E; Melles, Gerrit R J


    To evaluate the incidence and causes of anterior corneal surface irregularities after successful Descemet membrane endothelial keratoplasty (DMEK) and the efficacy of contact lens fitting in these cases. Tertiary referral center. Retrospective study of prospectively collected data. Eyes with a subnormal visual outcome or monocular diplopia after successful DMEK were fitted with a contact lens. These cases were evaluated with Pentacam rotating Scheimpflug camera imaging preoperatively and 6 months postoperatively, and outcomes were compared with those in a randomly selected DMEK control group. In a series of 262 surgeries, 23 eyes (21 patients) were fitted with contact lenses; the control group comprised 23 eyes. Indications for contact lens fitting included (1) obvious corneal surface irregularities due to preexisting corneal scarring, (2) surface irregularities associated with longstanding preoperative stromal edema, and (3) undetectable optical imperfections. The postoperative corrected distance visual acuity (CDVA) with spectacles improved after contact lens correction (PDutch Ophthalmic USA. No author has a financial or proprietary interest in any material or method mentioned. Copyright © 2013 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  19. Modeling and vibro-acoustic analysis of elastically restrained panel backed by irregular sound space (United States)

    Chen, Yuehua; Jin, G.; Feng, Zhimin; Liu, Zhigang


    A general analytical method is developed for the natural features and vibro-acoustic response analysis of an arbitrarily restrained rectangular plate backed by an irregular cavity. The modeling of the structure and the sound space are developed by employing the variational theory based on the sub-structure method. The irregular enclosure is disassembled into sub-cavities and the coupling formulae are deduced. The continuity conditions of both sound pressure and particle velocity at the coupling interface are exactly satisfied. The variational expressions of elastic boundary conditions of the panel are presented and thus the classical boundary conditions can be easily obtained by assigning appropriate elastic coupling coefficients. The vibration and sound pressure solutions are obtained by performing the Rayleigh-Ritz procedure. The accuracy and efficiency of the present method are validated by checking the present results against the finite element method (FEM) results for systems separately with right-angled trapezoidal and concave curved trapezoidal sub-cavity. It is shown that the present method is suitable for a system with an irregular cavity and an elastically restrained plate by exhibiting satisfactory accuracy, fast convergence speed while requiring small computation effort.

  20. Utility of a semi-scleral contact lens design in the management of the irregular cornea. (United States)

    Romero-Jiménez, Miguel; Flores-Rodríguez, Patricia


    To evaluate the utility of the Rose K2 XL semi-scleral contact lens (Menicon Co. Ltd., Nagoya, Japan) in the management of the irregular cornea. Twenty-seven subjects (34 eyes) with irregular corneas referred for contact lens fitting were evaluated. A diagnostic trial set was used in the fitting process. Once the trial lens was considered optimal, a final lens was ordered from the manufacturer with the necessary changes in power, edge lift and diameter. We analyzed visual acuity, number of lenses ordered and patients' ability to wear and handle lenses. Twenty-three subjects (30 eyes) were fitted with the Rose K2 XL lens. Four subjects (4 eyes) decided not to conclude the fitting process for different reasons. Average logMAR visual acuity without correction and with the lens was 0.82 and 0.09, respectively (plenses (range 1-3) were necessary to achieve the optimal fit. Nineteen eyes (63%) were fitted with the first lens ordered. Three subjects (13%) had problems with lens handling, and three subjects (4 eyes) abandoned the wear of the lenses after three months due to discomfort (3 eyes) and unsatisfactory visual acuity (1 eye), respectively. Follow-up ranged from 6 to 9 months. Rose K2 XL semi-scleral contact lens provides good visual acuity and comfort in patients with irregular corneas. Copyright © 2012 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.