Sample records for understanding content experimental

  1. Understanding Content-and-Structure

    NARCIS (Netherlands)

    Kamps, J.; Marx, M.J.; de Rijke, M.; Sigurbjörnsson, B.; Trotman, A.; Lalmas, M.; Fuhr, N.


    Document-centric XML is a mixture of text and structure. +With the increased availability of document-centric XML content comes a need for query facilities in which both structural constraints and constraints on the content of the documents can be expressed. This has generated considerable interest

  2. High Content Screening: Understanding Cellular Pathway

    International Nuclear Information System (INIS)

    Mohamed Zaffar Ali Mohamed Amiroudine; Daryl Jesus Arapoc; Zainah Adam; Shafii Khamis


    High content screening (HCS) is the convergence between cell-based assays, high-resolution fluorescence imaging, phase-contrast imaging of fixed- or live-cell assays, tissues and small organisms. It has been widely adopted in the pharmaceutical and biotech industries for target identification and validation and as secondary screens to reveal potential toxicities or to elucidate a drugs mechanism of action. By using the ImageXpress® Micro XLS System HCS, the complex network of key players controlling proliferation and apoptosis can be reduced to several sentinel markers for analysis. Cell proliferation and apoptosis are two key areas in cell biology and drug discovery research. Understanding the signaling pathways in cell proliferation and apoptosis is important for new therapeutic discovery because the imbalance between these two events is predominant in the progression of many human diseases, including cancer. The DNA binding dye DAPI is used to determine the nuclear size and nuclear morphology as well as cell cycle phases by DNA content. Images together with MetaXpress® analysis results provide a convenient and easy to use solution to high volume image management. In particular, HCS platform is beginning to have an important impact on early drug discovery, basic research in systems cell biology, and is expected to play a role in personalized medicine or revealing off-target drug effects. (author)

  3. Understanding Leadership: An Experimental-Experiential Model (United States)

    Hole, George T.


    Books about leadership are dangerous to readers who fantasize about being leaders or apply leadership ideas as if they were proven formulas. As an antidote, I offer an experimental framework in which any leadership-management model can be tested to gain experiential understanding of the model. As a result one can gain reality-based insights about…

  4. Adolescent literacy: learning and understanding content. (United States)

    Goldman, Susan R


    Learning to read--amazing as it is to small children and their parents--is one thing. Reading to learn, explains Susan Goldman of the University of Illinois at Chicago, is quite another. Are today's students able to use reading and writing to acquire knowledge, solve problems, and make decisions in academic, personal, and professional arenas? Do they have the literacy skills necessary to meet the demands of the twenty-first century? To answer these questions, Goldman describes the increasingly complex comprehension, reasoning skills, and knowledge that students need as they progress through school and surveys what researchers and educators know about how to teach those skills. Successfully reading to learn requires the ability to analyze, synthesize, and evaluate information from multiple sources, Goldman writes. Effective readers must be able to apply different knowledge, reading, and reasoning processes to different types of content, from fiction to history and science, to news accounts and user manuals. They must assess sources of information for relevance, reliability, impartiality, and completeness. And they must connect information across multiple sources. In short, successful readers must not only use general reading skills but also pay close attention to discipline-specific processes. Goldman reviews the evidence on three different instructional approaches to reading to learn: general comprehension strategies, classroom discussion, and disciplinary content instruction. She argues that building the literacy skills necessary for U.S. students to read comprehensively and critically and to learn content in a variety of disciplines should be a primary responsibility for all of the nation's teachers. But outside of English, few subject-area teachers are aware of the need to teach subject-area reading comprehension skills, nor have they had opportunities to learn them themselves. Building the capacity of all teachers to meet the literacy needs of today's students

  5. Understanding bimolecular machines: Theoretical and experimental approaches (United States)

    Goler, Adam Scott

    This dissertation concerns the study of two classes of molecular machines from a physical perspective: enzymes and membrane proteins. Though the functions of these classes of proteins are different, they each represent important test-beds from which new understanding can be developed by the application of different techniques. HIV1 Reverse Transcriptase is an enzyme that performs multiple functions, including reverse transcription of RNA into an RNA/DNA duplex, RNA degradation by the RNaseH domain, and synthesis of dsDNA. These functions allow for the incorporation of the retroviral genes into the host genome. Its catalytic cycle requires repeated large-scale conformational changes fundamental to its mechanism. Motivated by experimental work, these motions were studied theoretically by the application of normal mode analysis. It was observed that the lowest order modes correlate with largest amplitude (low-frequency) motion, which are most likely to be catalytically relevant. Comparisons between normal modes obtained via an elastic network model to those calculated from the essential dynamics of a series of all-atom molecular dynamics simulations show the self-consistency between these calculations. That similar conformational motions are seen between independent theoretical methods reinforces the importance of large-scale subdomain motion for the biochemical action of DNA polymerases in general. Moreover, it was observed that the major subunits of HIV1 Reverse Transcriptase interact quasi-harmonically. The 5HT3A Serotonin receptor and P2X1 receptor, by contrast, are trans-membrane proteins that function as ligand gated ion channels. Such proteins feature a central pore, which allows for the transit of ions necessary for cellular function across a membrane. The pore is opened by the ligation of binding sites on the extracellular portion of different protein subunits. In an attempt to resolve the individual subunits of these membrane proteins beyond the diffraction

  6. Fusion in computer vision understanding complex visual content

    CERN Document Server

    Ionescu, Bogdan; Piatrik, Tomas


    This book presents a thorough overview of fusion in computer vision, from an interdisciplinary and multi-application viewpoint, describing successful approaches, evaluated in the context of international benchmarks that model realistic use cases. Features: examines late fusion approaches for concept recognition in images and videos; describes the interpretation of visual content by incorporating models of the human visual system with content understanding methods; investigates the fusion of multi-modal features of different semantic levels, as well as results of semantic concept detections, fo

  7. Understanding Extraordinary Architectural Experiences through Content Analysis of Written Narratives

    Directory of Open Access Journals (Sweden)

    Brandon Richard Ro


    Full Text Available This study a identifies how people describe, characterize, and communicate in written form Extraordinary Architectural Experiences (EAE, and b expands the traditional qualitative approach to architectural phenomenology by demonstrating a quantitative method to analyze written narratives. Specifically, this study reports on the content analysis of 718 personal accounts of EAEs. Using a deductive, ‘theory-driven’ approach, these narratives were read, coded, and statistically analyzed to identify storyline structure, convincing power, and the relationship between subjective and objective experiential qualities used in the story-telling process. Statistical intercoder agreement tests were conducted to verify the reliability of the interpretations to approach the hard problem of “extraordinary aesthetics” in architecture empirically. The results of this study confirm the aesthetic nature of EAE narratives (and of told experiences by showing their higher dependence on external objective content (e.g., a building’s features and location rather than its internal subjective counterpart (e.g., emotions and sensations, which makes them more outwardly focused. The strong interrelationships and intercoder agreement between the thematic realms provide a unique aesthetic construct revealing EAE narratives as memorable, embodied, emotional events mapped by the externally focused content of place, social setting, time, and building features. A majority of EAE narratives were found to possess plot-structure along with significant relationships to objective-subjective content that further grounded their storylines. This study concludes that content analysis provides not only a valid method to understand written narratives about extraordinary architectural experiences quantitatively, but also a view as to how to map the unique nature of aesthetic phenomenology empirically.

  8. Increasing process understanding by analyzing complex interactions in experimental data

    DEFF Research Database (Denmark)

    Naelapaa, Kaisa; Allesø, Morten; Kristensen, Henning Gjelstrup


    There is a recognized need for new approaches to understand unit operations with pharmaceutical relevance. A method for analyzing complex interactions in experimental data is introduced. Higher-order interactions do exist between process parameters, which complicate the interpretation...... understanding of a coating process. It was possible to model the response, that is, the amount of drug released, using both mentioned techniques. However, the ANOVAmodel was difficult to interpret as several interactions between process parameters existed. In contrast to ANOVA, GEMANOVA is especially suited...... for modeling complex interactions and making easily understandable models of these. GEMANOVA modeling allowed a simple visualization of the entire experimental space. Furthermore, information was obtained on how relative changes in the settings of process parameters influence the film quality and thereby drug...

  9. Understanding Faculty to Improve Content Recruitment for Institutional Repositories (United States)

    Foster, Nancy Fried.; Gibbons, Susan


    Institutional repositories (IRs) offer many clear benefits yet faculty authors have not demonstrated much interest in depositing their content into them. Without the content, IRs will not succeed, because institutions will sustain IRs for only so long without evidence of success. A yearlong study of faculty members at the University of Rochester…

  10. How Augmented Reality Enables Conceptual Understanding of Challenging Science Content (United States)

    Yoon, Susan; Anderson, Emma; Lin, Joyce; Elinich, Karen


    Research on learning about science has revealed that students often hold robust misconceptions about a number of scientific ideas. Digital simulation and dynamic visualization tools have helped to ameliorate these learning challenges by providing scaffolding to understand various aspects of the phenomenon. In this study we hypothesize that…

  11. The Critical Role of Experimentation to Further SSA Understanding (United States)

    Donnelly, P.; Ash, A.


    Dstl has developed an approach to explore the challenges of understanding the fundamental principles of SSA through the design and execution of a series of national and international SSA experiments conducted since 2008. These have involved a number of nations within different multi-lateral constructs (such as Combined Space Operations [CSPO] and NATO), and have also served as test case scenarios in support of international SSA research collaboration. It has been found that this experimentally-driven approach has been successful in linking government R&D activities to actual operations with UK MOD; enabling enhanced cooperation with academia through the provision of access to sensors and data; as well as an understanding of the operational imperatives and constraints, not usually available or apparent to these institutions. The experiences of the Dstl team over the past 8 years have yielded a number of lessons learnt that we believe the wider international community would benefit from in relation to effective SSA operations, including how to generate closer relationships between communities across government, industry, academia and operators. This paper describes the overall Dstl approach to a series of SSA experiments designed to inform the UK MOD on the challenges and potential technical solutions related to SSA mission areas. It includes details of the participants, design and execution; and illustrates some major findings of each event to date. Lessons learnt pertinent to the AMOS and wider SSA community are presented that will inform the audience on how this approach may be adopted to meet other SSA scenarios. Finally, it presents the UK roadmap for future experiments identified as possible activities under the CSPO initiative and the EU Space Surveillance and Tracking programme.

  12. Mode Content Determination of Terahertz Corrugated Waveguides Using Experimentally Measured Radiated Field Patterns. (United States)

    Jawla, Sudheer K; Nanni, Emilio A; Shapiro, Michael A; Woskov, Paul P; Temkin, Richard J


    This work focuses on the accuracy of the mode content measurements in an overmoded corrugated waveguide using measured radiated field patterns. Experimental results were obtained at 250 GHz using a vector network analyzer with over 70 dB of dynamic range. The intensity and phase profiles of the fields radiated from the end of the 19 mm diameter helically tapped brass waveguide were measured on planes at 7, 10, and 13 cm from the waveguide end. The measured fields were back propagated to the waveguide aperture to provide three independent estimates of the field at the waveguide exit aperture. Projecting that field onto the modes of the guide determined the waveguide mode content. The three independent mode content estimates were found to agree with one another to an accuracy of better than ±0.3%. These direct determinations of the mode content were compared with indirect measurements using the experimentally measured amplitude in three planes, with the phase determined by a phase retrieval algorithm. The phase retrieval technique using the planes at 7, 10, and 13 cm yielded a mode content estimate in excellent agreement, within 0.3%, of the direct measurements. Phase retrieval results using planes at 10, 20, and 30 cm were less accurate due to truncation of the measurement in the transverse plane. The reported measurements benefited greatly from a precise mechanical alignment of the scanner with respect to the waveguide axis. These results will help to understand the accuracy of mode content measurements made directly in cold test and indirectly in hot test using the phase retrieval technique.

  13. College Students' Use of Science Content during Socioscientific Issues Negotiation: Impact of Evolution Understanding and Acceptance (United States)

    Fowler, Samantha R.


    The purpose of this study was to explore the evolution science content used during college students' negotiation of biology-based socioscientific issues (SSI) and examine how it related to students' conceptual understanding and acceptance of biological evolution. Specific research questions were, (1a) what specific evolutionary science content do…

  14. Individual shareholders’ understanding of the content of interim reports of South African listed retail companies

    Directory of Open Access Journals (Sweden)

    Johan GI Oberholster


    Full Text Available A number of studies conducted, and reports published, by international and local accounting bodies have found that the proliferation of disclosures in financial reports has hampered users’ understanding of these reports. The reports by accounting bodies also indicate that these users prefer more concise financial reports. These findings, in conjunction with a dearth of recent questionnaire-based research on whether individual shareholders understand the content of financial reports, resulted in this study on whether individual shareholders understand the content of interim reports. The study provides empirical proof that a sound knowledge of business, accounting and economic matters is a prerequisite for understanding interim reports in the case of individual shareholders. The results of the study indicate that individual shareholders have a limited understanding of the content of interim reports as a whole, and that a good knowledge of business and economic matters and of accounting results in an improved understanding of the content of interim reports. In particular, specialisation in accounting in undergraduate and postgraduate degrees, professional qualifications, and work experience in the financial field improve the understanding of individual shareholders.

  15. Mind over matter: The intellectual content of experimental physics

    International Nuclear Information System (INIS)

    Telegdi, V.L.


    The author presents a new way of teaching experimental physics using Selenyi's experiment on dipole radiation, Michelson's optical demonstration of the earth rotation, the direct measurement of the helicity of the electron neutrino by Goldhaber, grodzins, and Sunyar and the determination of the helicity of the muonic neutrino by Grenas et al. (HSI)

  16. Understanding human quality judgment in assessing online forum contents for thread retrieval purpose (United States)

    Ismail, Zuriati; Salim, Naomie; Huspi, Sharin Hazlin


    Compared to traditional materials or journals, user-generated contents are not peer-reviewed. Lack of quality control and the explosive growth of web contents make the task of finding quality information on the web especially critical. The existence of new facilities for producing web contents such as forum makes this issue more significant. This study focuses on online forums threads or discussion, where the forums contain valuable human-generated information in a form of discussions. Due to the unique structure of the online forum pages, special techniques are required to organize and search for information in these forums. Quality biased retrieval is a retrieval approach that search for relevant document and prioritized higher quality documents. Despite major concern of quality content and recent development of quality biased retrieval, there is an urgent need to understand how quality content is being judged, for retrieval and performance evaluation purposes. Furthermore, even though there are various studies on the quality of information, there is no standard framework that has been established. The primary aim of this paper is to contribute to the understanding of human quality judgment in assessing online forum contents. The foundation of this study is to compare and evaluate different frameworks (for quality biased retrieval and information quality). This led to the finding that many quality dimensions are redundant and some dimensions are understood differently between different studies. We conducted a survey on crowdsourcing community to measure the importance of each quality dimensions found in various frameworks. Accuracy and ease of understanding are among top important dimensions while threads popularity and contents manipulability are among least important dimensions. This finding is beneficial in evaluating contents of online forum.

  17. Describing Instrumental Music Teachers' Thinking: Implications for Understanding Pedagogical Content Knowledge (United States)

    Millican, J. Si


    Pedagogical content knowledge, the particular ways that teachers understand their subjects in order to instruct others, has been described and explored in the math and science education fields in some depth, yet little research exists illustrating this concept in music instruction. I used a descriptive approach to explore expert beginning band…

  18. Improvement of the experimental content in Laser Principle and its Application (United States)

    Niu, Chun-hui; Lang, Xiao-ping; Lv, Yong; Meng, Hao


    Experimental teaching content of Laser Principle and Its Application is proposed to improve from experimental teaching devices and experimental guide book. At first, a experimental system of laser-diode-pumped solid-state laser is designed and manufactured. Separate optical components are adopted in the designed experimental system and students can put these optical components on every place and their ability to establish and adjust optical path can be enhanced. Moreover, experimental education outline of Laser Principle and Its Application is revised and improved. At last, experimental guide book for the designed and manufactured experimental device is written. The experimental teaching innovation will improve experimental teaching effect and quality of Laser Principle and Its Application.

  19. Carbon and nutrient contents in soils from the Kings River Experimental Watersheds, Sierra Nevada Mountains, California (United States)

    D.W. Johnson; C.T. Hunsaker; D.W. Glass; B.M. Rau; B.A. Roath


    Soil C and nutrient contents were estimated for eight watersheds in two sites (one high elevation, Bull, and one low elevation, Providence) in the Kings River Experimental Watersheds in the western Sierra Nevada Mountains of California. Eighty-seven quantitative pits were dug to measure soil bulk density and total rock content, while three replicate surface samples...

  20. Scientific Thinking in Elementary School: Children's Social Cognition and Their Epistemological Understanding Promote Experimentation Skills (United States)

    Osterhaus, Christopher; Koerber, Susanne; Sodian, Beate


    Do social cognition and epistemological understanding promote elementary school children's experimentation skills? To investigate this question, 402 children (ages 8, 9, and 10) in 2nd, 3rd, and 4th grades were assessed for their experimentation skills, social cognition (advanced theory of mind [AToM]), epistemological understanding (understanding…

  1. Children's Understanding of Experimental Contrast and Experimental Control: An Inventory for Primary School (United States)

    Osterhaus, Christopher; Koerber, Susanne; Sodian, Beate


    Experimentation skills are a central component of scientific thinking, and many studies have investigated whether and when primary-school children develop adequate experimentation strategies. However, the answers to these questions vary substantially depending on the type of task that is used: while discovery tasks, which require children to…

  2. Understanding primary school science teachers' pedagogical content knowledge: The case of teaching global warming (United States)

    Chordnork, Boonliang; Yuenyong, Chokchai


    This aim of this research was to investigate primary school science teachers understanding and teaching practice as well as the influence on teaching and learning a topic like global warming. The participants were four primary science teachers, who were not graduated in science education. Methodology was the case study method, which was under the qualitative research regarded from interpretive paradigm. Data were collected by openended questionnaire, semi-structure interview, and document colleting. The questionnaire examined teachers' background, teachers' understanding of problems and threats of science teaching, desiring of development their PCK, sharing the teaching approaches, and their ideas of strength and weakness. a semi-structured interview was conducted based on the approach for capturing PCK of Loughran [23] content representation (CoRe). And, the document was collected to clarify what evidence which was invented to effect on students' learning. These document included lesson plan, students' task, and painting about global warming, science projects, the picture of activities of science learning, the exercise and test. Data analysis employed multiple approach of evidence looking an issue from each primary science teachers and used triangulation method to analyze the data with aiming to make meaning of teachers' representation of teaching practice. These included descriptive statistics, CoRe interpretation, and document analysis. The results show that teachers had misunderstanding of science teaching practice and they has articulated the pedagogical content knowledge in terms of assessment, goal of teaching and linking to the context of socio cultural. In contrast, knowledge and belief of curriculum, students' understanding of content global warming, and strategies of teaching were articulated indistinct by non-graduate science teacher. Constructing opportunities for personal development, the curiosity of the student learning center, and linking context

  3. Scaffolded Instruction Improves Student Understanding of the Scientific Method & Experimental Design (United States)

    D'Costa, Allison R.; Schlueter, Mark A.


    Implementation of a guided-inquiry lab in introductory biology classes, along with scaffolded instruction, improved students' understanding of the scientific method, their ability to design an experiment, and their identification of experimental variables. Pre- and postassessments from experimental versus control sections over three semesters…

  4. Scientific thinking in elementary school: Children's social cognition and their epistemological understanding promote experimentation skills. (United States)

    Osterhaus, Christopher; Koerber, Susanne; Sodian, Beate


    Do social cognition and epistemological understanding promote elementary school children's experimentation skills? To investigate this question, 402 children (ages 8, 9, and 10) in 2nd, 3rd, and 4th grades were assessed for their experimentation skills, social cognition (advanced theory of mind [AToM]), epistemological understanding (understanding the nature of science), and general information-processing skills (inhibition, intelligence, and language abilities) in a whole-class testing procedure. A multiple indicators multiple causes model revealed a significant influence of social cognition (AToM) on epistemological understanding, and a McNemar test suggested that children's development of AToM is an important precursor for the emergence of an advanced, mature epistemological understanding. Children's epistemological understanding, in turn, predicted their experimentation skills. Importantly, this relation was independent of the common influences of general information processing. Significant relations between experimentation skills and inhibition, and between epistemological understanding, intelligence, and language abilities emerged, suggesting that general information processing contributes to the conceptual development that is involved in scientific thinking. The model of scientific thinking that was tested in this study (social cognition and epistemological understanding promote experimentation skills) fitted the data significantly better than 2 alternative models, which assumed nonspecific, equally strong relations between all constructs under investigation. Our results support the conclusion that social cognition plays a foundational role in the emergence of children's epistemological understanding, which in turn is closely related to the development of experimentation skills. Our findings have significant implications for the teaching of scientific thinking in elementary school and they stress the importance of children's epistemological understanding in

  5. Understanding organometallic reaction mechanisms and catalysis experimental and computational tools computational and experimental tools

    CERN Document Server

    Ananikov, Valentin P


    Exploring and highlighting the new horizons in the studies of reaction mechanisms that open joint application of experimental studies and theoretical calculations is the goal of this book. The latest insights and developments in the mechanistic studies of organometallic reactions and catalytic processes are presented and reviewed. The book adopts a unique approach, exemplifying how to use experiments, spectroscopy measurements, and computational methods to reveal reaction pathways and molecular structures of catalysts, rather than concentrating solely on one discipline. The result is a deeper

  6. Understanding the bias between moisture content by oven drying and water content by Karl Fischer titration at moisture equilibrium (United States)

    Multiple causes of the difference between equilibrium moisture and water content have been found. The errors or biases were traced to the oven drying procedure to determine moisture content. The present paper explains the nature of the biases in oven drying and how it is possible to suppress one ...

  7. Effect of whole-body gamma radiation on tissue sulfhydryl contents in experimental rats

    International Nuclear Information System (INIS)

    Sarkar, S.R.; Singh, L.R.; Uniyal, B.P.


    It has been postulated that vital constituents of cell membranes concerned with the maintenance of cellular integrity are affected by ionizing radiation. Sulfhydryl contents, which form an integral component of cell membranes play vital roles in maintaining cellular integrity. The purpose was to evaluate non-protein and protein sulfhydryl contents in tissues of irradiated rats. Adult male Sprague Dawley rats were exposed to whole-body gamma irradiation of 4 Gy and 10 Gy and non-protein and protein sulfhydryl contents of blood, heart and spleen were studied on postirradiation day 1, 3 and 6. Both groups of experimental rats exhibited unchanged blood non-protein sulfhydryl contents on first day after irradiation with significant diminution subsequently. In contrast, blood protein sulfhydryl groups of both groups of rats were increased on first day post exposure, which became normal on sixth day. Myocardial non-protein and protein sulfhydryl contents of both groups of rats remained unchanged in the initial stage of radiation exposure indicating radioresistance nature of rat heart. Both groups of rats demonstrated biphasic nature of non-protein sulfhydryl contents in spleen, asrevealed by initial increase with subsequent decrease. Protein sulfhydryl contents of rats of 4 Gy group showed significant diminution post exposure throughout, while the same of 10 Gy behaved in opposite way. (author)

  8. Estimation of Molten Content of the Spray Stream from Analysis of Experimental Particle Diagnostics (United States)

    Srinivasan, Vasudevan; Sampath, Sanjay


    Particle melting is one of the key issues in air plasma spray processing of high temperature ceramics such as Yttria Stabilized Zirconia (YSZ). The significance of assessing, monitoring, and controlling the molten content in spray stream on achieving an efficient process and reproducible coating characteristics and properties is known. This study aims to estimate the molten content of the spray stream (as an ensemble) from experimental measurement of in-flight (individual) particle characteristics. In a previous study by Streibl et al. the presence of melting signature in the particle temperature distribution was observed, which has been confirmed by simulation and through independent experimental observation by Mauer et al. Based on this observation, the particle temperature distribution could be delineated into the different achievable particle states in-flight (unmolten, partially molten, and completely molten) to a first approximation. This in-turn would enable estimation of the molten content in the spray stream. Thus obtained percentage molten content (referred in this study as Spray Stream Melting Index—SSMI) has been observed to correlate well with the experimentally measured deposition efficiency for a wide range of process conditions and feedstock characteristics. The implications of estimating SSMI for other materials and processes are also discussed.

  9. It's not all about moral reasoning: Understanding the content of Moral Case Deliberation. (United States)

    Svantesson, Mia; Silén, Marit; James, Inger


    Moral Case Deliberation is one form of clinical ethics support described as a facilitator-led collective moral reasoning by healthcare professionals on a concrete moral question connected to their practice. Evaluation research is needed, but, as human interaction is difficult to standardise, there is a need to capture the content beyond moral reasoning. This allows for a better understanding of Moral Case Deliberation, which may contribute to further development of valid outcome criteria and stimulate the normative discussion of what Moral Case Deliberation should contain. To explore and compare the content beyond moral reasoning in the dialogue in Moral Case Deliberation at Swedish workplaces. A mixed-methods approach was applied for analysing audio-recordings of 70 periodic Moral Case Deliberation meetings at 10 Swedish workplaces. Moral Case Deliberation facilitators and various healthcare professions participated, with registered nurses comprising the majority. Ethical considerations: No objection to the study was made by an Ethical Review Board. After oral and written information was provided, consent to be recorded was assumed by virtue of participation. Other than 'moral reasoning' (median (md): 45% of the spoken time), the Moral Case Deliberations consisted of 'reflections on the psychosocial work environment' to a varying extent (md: 29%). Additional content comprised 'assumptions about the patient's psychosocial situation' (md: 6%), 'facts about the patient's situation' (md: 5%), 'concrete problem-solving' (md: 6%) and 'process' (md: 3%). The findings suggest that a restorative function of staff's wellbeing in Moral Case Deliberation is needed, as this might contribute to good patient care. This supports outcome criteria of improved emotional support, which may include relief of moral distress. However, facilitators need a strategy for how to proceed from the participants' own emotional needs and to develop the use of their emotional knowing to focus on

  10. Understanding the spatial distribution of factors controlling topsoil organic carbon content in European soils. (United States)

    Rial, M; Martínez Cortizas, A; Rodríguez-Lado, L


    Soil Organic Carbon (SOC) constitutes the largest terrestrial carbon pool. The understanding of its dynamics and the environmental factors that influence its behaviour as sink or source of atmospheric CO 2 is crucial to quantify the carbon budget at the global scale. At the European scale, most of the existing studies to account for SOC stocks are centred in the fitting of predictive model to ascertain the distribution of SOC. However, the development of methodologies for monitoring and identifying the environmental factors that control SOC storage in Europe remains a key research challenge. Here we present a modelling procedure for mapping and monitoring SOC contents that uses Visible-Near Infrared (VNIR) spectroscopic measurements and a series of environmental covariates to ascertain the key environmental processes that have a major contribution into SOC sequestration processes. Our results show that it follows a geographically non-stationary process in which the influencing environmental factors have different weights depending on the spatial location. This implies that SOC stock modelling should not rely on a single model but on a combination of different statistical models depending on the environmental characteristics of each area. A cluster classification of European soils in relation to those factors resulted in the determination of four groups for which specific models have been obtained. Differences in climate, soil pH, content of coarse fragments or land cover type are the main factors explaining the differences in SOC in topsoil from Europe. We found that climatic conditions are the main driver of SOC storage at the continental scale, but we also found that parameters like land cover type influence SOC content found at the local scales in certain areas. Our methodology developed at continental scale could be used in future research aimed to improve the predictive performance of SOC assessments at European scale. Copyright © 2017 Elsevier B.V. All

  11. Understanding Consumer Interaction on Instagram: The Role of Satisfaction, Hedonism, and Content Characteristics. (United States)

    Casaló, Luis V; Flavián, Carlos; Ibáñez-Sánchez, Sergio


    The increasing relevance of Instagram and its growing adoption among top brands suggest an effort to better understand consumers' behaviors within this context. The purpose of this study is to examine the role of perceived hedonism and satisfaction in determining consumers' intentions to interact and their actual interaction behaviors (the number of likes, by tapping a heart icon, and comments) in a brand's official Instagram account. Also, we investigate the effect of consumer perceptions about the characteristics of the content generated in the account (perceived originality, quantity, and quality) on their perceived hedonism and satisfaction. Data were collected in two stages from 808 members of a fashion brand's official Instagram account. First, participants answered an online questionnaire to evaluate their perceptions, satisfaction, and interaction intentions. Second, 1 month later, we measure the number of likes and comments done by each participant in the brand's official Instagram account during that month. Using partial least squares to analyze the data, perceived hedonism is found to affect both satisfaction and the intention to interact in Instagram, which in turn influences actual behavior. Besides, perceived originality is the most relevant content characteristic to develop perceived hedonism. These findings offer managers a general vision of consumers' behaviors on Instagram, highlighting the importance of hedonism to create a satisfactory experience.

  12. Experimental determination of the empirical formula and energy content of unknown organics in waste streams

    International Nuclear Information System (INIS)

    Shizas, I.; Kosmatos, A.; Bagley, D.M.


    Two experimental methods are described in this paper: one for determining the empirical formula, and one for determining the energy content of unknown organics in waste streams. The empirical formula method requires volatile solids (VS), chemical oxygen demand (COD), total organic carbon (TOC), and total Kjeldahl nitrogen (TKN) to be measured for the waste; the formula can then be calculated from these values. To determine the energy content of the organic waste, bomb calorimetry was used with benzoic acid as a combustion aid. The results for standard compounds (glucose, propionic acid, L-arginine, and benzoic acid) were relatively good. The energy content measurement for wastewater and sludges had good reproducibility (i.e. 1.0 to 3.2% relative standard deviation for triplicate samples). Trouble encountered in the measurement of the empirical formulae of the waste samples was possibly due to difficulties with the TOC test; further analysis of this is required. (author)

  13. Bringing content understanding into usability testing in complex application domains—a case study in eHealth

    DEFF Research Database (Denmark)

    Andersen, Simon Bruntse; Rasmussen, Claire Kirchert; Frøkjær, Erik


    A usability evaluation technique, Cooperative Usability Testing with Questions of Understanding (CUT with QU) intended to illuminate users’ ability to understand the content information of an application is proposed. In complex application domains as for instance the eHealth domain, this issue...... of users’ content understanding is sometimes crucial, and thus should be carefully evaluated. Unfortunately, conventional usability evaluation techniques do not address challenges of content understanding. In a case study within eHealth, specifically the setting of a rehabilitation clinic involving...... the participation of four physiotherapists and four clients in a period of 3.5 months, it was demonstrated how CUT with QU can complement conventional usability testing and provide insight into users’ challenges with understanding of a new complex eHealth application. More experiments in other complex application...

  14. Hearing voices and listening to what they say: the importance of voice content in understanding and working with distressing voices. (United States)

    Beavan, Vanessa; Read, John


    The content of auditory hallucinations is sometimes dismissed as having little diagnostic/therapeutic importance. There is growing evidence that voice content may be crucial to understanding and working therapeutically with this experience. The aim of the present study is to explore, in a general population sample, the content and impact of voice-hearers' auditory hallucinations. A self-selected sample of 154 participants completed questionnaires about voice-hearing. A subsample of 50 participants completed semi-structured interviews. Participants experienced a range of voice content of high personal relevance, with most experiencing both positive and negative content. Voice content was the only significant predictor of emotional distress and the strongest predictor of contact with mental health services. These findings suggest that content is an important characteristic of auditory hallucinations and should be explored with voice-hearers who find themselves in clinical settings.

  15. Determination of Soil Moisture Content using Laboratory Experimental and Field Electrical Resistivity Values (United States)

    Hazreek, Z. A. M.; Rosli, S.; Fauziah, A.; Wijeyesekera, D. C.; Ashraf, M. I. M.; Faizal, T. B. M.; Kamarudin, A. F.; Rais, Y.; Dan, M. F. Md; Azhar, A. T. S.; Hafiz, Z. M.


    The efficiency of civil engineering structure require comprehensive geotechnical data obtained from site investigation. In the past, conventional site investigation was heavily related to drilling techniques thus suffer from several limitations such as time consuming, expensive and limited data collection. Consequently, this study presents determination of soil moisture content using laboratory experimental and field electrical resistivity values (ERV). Field and laboratory electrical resistivity (ER) test were performed using ABEM SAS4000 and Nilsson400 soil resistance meter. Soil sample used for resistivity test was tested for characterization test specifically on particle size distribution and moisture content test according to BS1377 (1990). Field ER data was processed using RES2DINV software while laboratory ER data was analyzed using SPSS and Excel software. Correlation of ERV and moisture content shows some medium relationship due to its r = 0.506. Moreover, coefficient of determination, R2 analyzed has demonstrate that the statistical correlation obtain was very good due to its R2 value of 0.9382. In order to determine soil moisture content based on statistical correlation (w = 110.68ρ-0.347), correction factor, C was established through laboratory and field ERV given as 19.27. Finally, this study has shown that soil basic geotechnical properties with particular reference to water content was applicably determined using integration of laboratory and field ERV data analysis thus able to compliment conventional approach due to its economic, fast and wider data coverage.

  16. Contents

    Directory of Open Access Journals (Sweden)

    Editor IJRED


    Full Text Available International Journal of Renewable Energy Development Volume 1             Number 3            October 2012                ISSN 2252- 4940   CONTENTS OF ARTICLES page Design and Economic Analysis of a Photovoltaic System: A Case Study 65-73 C.O.C. Oko , E.O. Diemuodeke, N.F. Omunakwe, and E. Nnamdi     Development of Formaldehyde Adsorption using Modified Activated Carbon – A Review 75-80 W.D.P Rengga , M. Sudibandriyo and M. Nasikin     Process Optimization for Ethyl Ester Production in Fixed Bed Reactor Using Calcium Oxide Impregnated Palm Shell Activated Carbon (CaO/PSAC 81-86 A. Buasri , B. Ksapabutr, M. Panapoy and N. Chaiyut     Wind Resource Assessment in Abadan Airport in Iran 87-97 Mojtaba Nedaei       The Energy Processing by Power Electronics and its Impact on Power Quality 99-105 J. E. Rocha and B. W. D. C. Sanchez       First Aspect of Conventional Power System Assessment for High Wind Power Plants Penetration 107-113 A. Merzic , M. Music, and M. Rascic   Experimental Study on the Production of Karanja Oil Methyl Ester and Its Effect on Diesel Engine 115-122 N. Shrivastava,  , S.N. Varma and M. Pandey  

  17. Relative permeability of fractured wellbore cement: an experimental investigation using electrical resistivity monitoring for moisture content (United States)

    Um, W.; Rod, K. A.; Strickland, C. E.


    Permeability is a critical parameter needed to understand flow in subsurface environments; it is particularly important in deep subsurface reservoirs where multiphase fluid flow is common, such as carbon sequestration and geothermal reservoirs. Cement is used in the annulus of wellbores due to its low permeable properties to seal aquifers, reducing leaks to adjacent strata. Extreme subsurface environments of CO2 storage and geothermal production conditions will eventually reduce the cement integrity, propagating fracture networks and increasing the permeability for air and/or water. To date, there have been no reproducible experimental investigations of relative permeability in fractured wellbore cement published. To address this gap, we conducted a series of experiments using fractured Portland cement monoliths with increasing fracture networks. The monolith cylinder sides were jacketed with heavy-duty moisture-seal heat-shrink tubing, then fractured using shear force applied via a hydraulic press. Fractures were generated with different severity for each of three monoliths. Stainless steel endcaps were fixed to the monoliths using the same shrink-wrapped jacket. Fracture characteristics were determined using X-ray microtomography and image analysis. Flow controllers were used to control flow of water and air to supply continuous water or water plus air, both of which were delivered through the influent end cap. Effluent air flow was monitored using a flow meter, and water flow was measured gravimetrically. To monitor the effective saturation of the fractures, a RCON2 concrete bulk electrical resistivity test device was attached across both endcaps and a 0.1M NaNO3 brine was used as the transport fluid to improve resistivity measurements. Water content correlated to resistivity measurements with a r2 > 0.96. Data from the experiments was evaluated using two relative permeability models, the Corey-curve, often used for modeling relative permeability in porous media

  18. Thermophysical properties of yacon (Smallanthus sonchifolius: experimental determination and effect of moisture content

    Directory of Open Access Journals (Sweden)

    Camila Augusto Perussello


    Full Text Available The knowledge about thermophysical properties of foods is especially important in thermal processing, influencing the design, optimization and cost reduction of the process, as well as the quality and safety of the final product. This article deals with the determination of some thermophysical properties of yacon, namely, specific mass, specific heat, thermal conductivity and thermal diffusivity during the osmo-convective drying. Yacon is a root with approximately 90% w.b. of moisture content, whose high concentration of fructooligosacharydes and antioxidants has gained attention in the food research field. Yacon slices were osmotically dehydrated for 2 hours in a sucralose solution and then dried in a convective tray dryer for 2 hours, varying the osmotic solution’s temperature and stirring rate and temperature of the drying air. All thermophysical properties were determined during the drying process at 30-minute intervals. The thermophysical properties were determined not only experimentally but also calculated by models available in literature based on the product’s centesimal composition. A satisfactory agreement between experimental and predicted results was obtained. Further, empirical models obtained by nonlinear regression were successfully fitted to the experimental data, as a function of moisture content, within a 94% - 3% w.b. range.

  19. Content of selected amino acids in the gastrocnemius muscle during experimental hypothyroidism in rats

    Directory of Open Access Journals (Sweden)

    Gołyński Marcin


    Full Text Available Introduction: Thyroid hormones affect protein turnover, and in the case of hypothyroidism a decrease in protein synthesis and reduced release of certain amino acids from skeletal muscles are observed. Changes in the amino acid system of skeletal muscles may be responsible for the occurrence of muscle disorders. Material and Methods: The study measured the content of selected amino acids in the gastrocnemius muscle of Wistar rats during experimental hypothyroidism induced by oral administration of methimazole at a concentration of 0.05% in drinking water for 90 d. The rats were divided into four groups: E1 (n = 6 - experimental males, E2 (n = 6 - experimental females, C1 (n = 6 - control males, and C2 (n = 6 control females. Results: A statistically significant reduction occurred in leucine, isoleucine, and 1-methylhistidine levels in males, and 1-methylhistidine in females, in comparison to the control groups. Conclusion: The hypothyroidism-induced changes in amino acid content may be responsible for the occurrence of skeletal muscle function disorders.

  20. Content

    DEFF Research Database (Denmark)

    Keiding, Tina Bering

    Aim, content and methods are fundamental categories of both theoretical and practical general didactics. A quick glance in recent pedagogical literature on higher education, however, reveals a strong preoccupation with methods, i.e. how teaching should be organized socially (Biggs & Tang, 2007......, is subordinating content to methods as seen in modern didactics, hereby transforming content to a medium for achievement of learning-to-learn skills rather than something valuable in its own right. At the level of general didactics quite few attempts have been made to formulate criteria and categories...... secondary levels. In subject matter didactics, the question of content is more developed, but it is still mostly confined to teaching on lower levels. As for higher education didactics, discussions on selection of content are almost non-existent on the programmatic level. Nevertheless, teachers are forced...

  1. Gender, experimenter gender and medium of report influence the content of autobiographical memory report. (United States)

    Grysman, Azriel; Denney, Amelia


    In this study, we examined the role of context in autobiographical memory narratives, specifically as it pertains to gender among emerging adults. Male and female participants reported stressful events in their lives in the presence of an experimenter, and were randomly assigned either to report events verbally or type them, and to report in the presence of a male or female experimenter. Narratives were coded for factual and interpretive content. Results revealed that men verbally reporting to women reported longer narratives than all other groups. Women's narrative length did not vary by medium of report or conversational partner, but women used proportionally fewer internal state phrases when verbally reporting to men than when reporting to women. Women also used proportionally fewer evaluative statements in verbal reports than in typed narratives. Of these important interactions among context, gender, and experimenter gender, some findings, such as men's longer narratives and women's reduced internal states, were counter to expectations. These findings highlight the importance of methodological influences in autobiographical memory studies, in regard to both the context generated by experimental methods, and how gender differences are understood.

  2. Population-reaction model and microbial experimental ecosystems for understanding hierarchical dynamics of ecosystems. (United States)

    Hosoda, Kazufumi; Tsuda, Soichiro; Kadowaki, Kohmei; Nakamura, Yutaka; Nakano, Tadashi; Ishii, Kojiro


    Understanding ecosystem dynamics is crucial as contemporary human societies face ecosystem degradation. One of the challenges that needs to be recognized is the complex hierarchical dynamics. Conventional dynamic models in ecology often represent only the population level and have yet to include the dynamics of the sub-organism level, which makes an ecosystem a complex adaptive system that shows characteristic behaviors such as resilience and regime shifts. The neglect of the sub-organism level in the conventional dynamic models would be because integrating multiple hierarchical levels makes the models unnecessarily complex unless supporting experimental data are present. Now that large amounts of molecular and ecological data are increasingly accessible in microbial experimental ecosystems, it is worthwhile to tackle the questions of their complex hierarchical dynamics. Here, we propose an approach that combines microbial experimental ecosystems and a hierarchical dynamic model named population-reaction model. We present a simple microbial experimental ecosystem as an example and show how the system can be analyzed by a population-reaction model. We also show that population-reaction models can be applied to various ecological concepts, such as predator-prey interactions, climate change, evolution, and stability of diversity. Our approach will reveal a path to the general understanding of various ecosystems and organisms. Copyright © 2015 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

  3. Analyzing Public Discourse: Using Media Content Analysis to Understand the Policy Process (United States)

    Saraisky, Nancy Green


    One of the most basic and obvious sources of data for education policy analysis is text. This article discusses content analysis as an important part of the methodological toolbox for elucidating patterns and trends about education policy. Focusing specifically on media, I show how media content analysis can produce nuanced insights about the ways…

  4. Experimental Warming Decreases the Average Size and Nucleic Acid Content of Marine Bacterial Communities

    KAUST Repository

    Huete-Stauffer, Tamara M.


    Organism size reduction with increasing temperature has been suggested as a universal response to global warming. Since genome size is usually correlated to cell size, reduction of genome size in unicells could be a parallel outcome of warming at ecological and evolutionary time scales. In this study, the short-term response of cell size and nucleic acid content of coastal marine prokaryotic communities to temperature was studied over a full annual cycle at a NE Atlantic temperate site. We used flow cytometry and experimental warming incubations, spanning a 6°C range, to analyze the hypothesized reduction with temperature in the size of the widespread flow cytometric bacterial groups of high and low nucleic acid content (HNA and LNA bacteria, respectively). Our results showed decreases in size in response to experimental warming, which were more marked in 0.8 μm pre-filtered treatment rather than in the whole community treatment, thus excluding the role of protistan grazers in our findings. Interestingly, a significant effect of temperature on reducing the average nucleic acid content (NAC) of prokaryotic cells in the communities was also observed. Cell size and nucleic acid decrease with temperature were correlated, showing a common mean decrease of 0.4% per °C. The usually larger HNA bacteria consistently showed a greater reduction in cell and NAC compared with their LNA counterparts, especially during the spring phytoplankton bloom period associated to maximum bacterial growth rates in response to nutrient availability. Our results show that the already smallest planktonic microbes, yet with key roles in global biogeochemical cycling, are likely undergoing important structural shrinkage in response to rising temperatures.

  5. Tools for Science Inquiry Learning: Tool Affordances, Experimentation Strategies, and Conceptual Understanding (United States)

    Bumbacher, Engin; Salehi, Shima; Wieman, Carl; Blikstein, Paulo


    Manipulative environments play a fundamental role in inquiry-based science learning, yet how they impact learning is not fully understood. In a series of two studies, we develop the argument that manipulative environments (MEs) influence the kind of inquiry behaviors students engage in, and that this influence realizes through the affordances of MEs, independent of whether they are physical or virtual. In particular, we examine how MEs shape college students' experimentation strategies and conceptual understanding. In study 1, students engaged in two consecutive inquiry tasks, first on mass and spring systems and then on electric circuits. They either used virtual or physical MEs. We found that the use of experimentation strategies was strongly related to conceptual understanding across tasks, but that students engaged differently in those strategies depending on what ME they used. More students engaged in productive strategies using the virtual ME for electric circuits, and vice versa using the physical ME for mass and spring systems. In study 2, we isolated the affordance of measurement uncertainty by comparing two versions of the same virtual ME for electric circuits—one with and one without noise—and found that the conditions differed in terms of productive experimentation strategies. These findings indicate that measures of inquiry processes may resolve apparent ambiguities and inconsistencies between studies on MEs that are based on learning outcomes alone.

  6. Clearance of 99mTc-DTPA and experimentally increased alveolar surfactant content

    International Nuclear Information System (INIS)

    Bos, J.A.H.; Wollmer, P.; Bakker, W.; Hannappel, E.; Lachmann, B.


    The authors measured clearance of 99m Tc-labeled diethylenetriamine pentaacetic acid ( 99m Tc-DTPA) in rabbits with experimentally increased alveolar surfactant content. In one group of animals, surfactant production was increased by treatment with ambroxol, and another group of animals was treated with tracheal instillation of natural surfactant. A group of untreated control animals and animals treated with instillation of saline were also studied. Clearance was measured during standard conditions of mechanical ventilation and during ventilation with large tidal volumes. In ambroxol- and surfactant-treated groups, clearance rate was reduced compared with untreated control animals. In contrast, clearance rate increased after saline instillation. The differences were observed at both modes of ventilation. The findings indicate that the pulmonary surfactant system is a rate-limiting factor for the clearance of 99m Tc-DTPA and that the volume dependence of clearance is not explained by stretching of the alveolar wall only. 28 refs., 2 figs., 1 tab

  7. A Fuzzy Color-Based Approach for Understanding Animated Movies Content in the Indexing Task

    Directory of Open Access Journals (Sweden)

    Vasile Buzuloiu


    Full Text Available This paper proposes a method for detecting and analyzing the color techniques used in the animated movies. Each animated movie uses a specific color palette which makes its color distribution one major feature in analyzing the movie content. The color palette is specially tuned by the author in order to convey certain feelings or to express artistic concepts. Deriving semantic or symbolic information from the color concepts or the visual impression induced by the movie should be an ideal way of accessing its content in a content-based retrieval system. The proposed approach is carried out in two steps. The first processing step is the low-level analysis. The movie color content gets represented with several global statistical parameters computed from the movie global weighted color histogram. The second step is the symbolic representation of the movie content. The numerical parameters obtained from the first step are converted into meaningful linguistic concepts through a fuzzy system. They concern mainly the predominant hues of the movie, some of Itten’s color contrasts and harmony schemes, color relationships and color richness. We use the proposed linguistic concepts to link to given animated movies according to their color techniques. In order to make the retrieval task easier, we also propose to represent color properties in a graphical manner which is similar to the color gamut representation. Several tests have been conducted on an animated movie database.

  8. Content of metals and organic acids from experimental sparkling white wine

    Directory of Open Access Journals (Sweden)

    Focea Mihai Cristian


    Full Text Available This work is focused on the study of the influence of different strains of yeasts on the concentration of organic acids, metallic content, and other physical-chemical parameters from experimental sparkling white wines produced by traditional method (bottle fermented. This study was required due to climatic conditions varying from year to year, generating grape harvests with very high alcoholic potential, and very low values for total acidity. In this case, a Muscat Ottonel grape must was used and passed by a reverse osmosis process. The obtained permeate was mixed with a calculated amount of the concentrate to generate a must with a potential of 10.5% (v/v alcohol, in order o to obtain the base wine for the second fermentation. After fermentation, the wine was treated to get tartaric, protein and microbiological stabilization. For the second fermentation four different strains of yeast species Saccharomyces cerevisiae were used. Bottle fermentation and storage was performed at a constant temperature of approximately 12 °C. After six months of storage, sparkling wine samples were analyzed. The metal content was determined using AAS method, and organic acid concentration was determined by a HPLC method. The main physical-chemical characteristics were determined (alcohol concentration, total acidity, volatile acidity, total dry extract, free SO2, total SO2, density, pH, conductivity based on OIV methods. The results obtained indicated significant differences of the analyzed parameters.

  9. Adsorption of hexane isomers on MFI type zeolites at ambient temperature: Understanding the aluminium content effect

    NARCIS (Netherlands)

    Ferreira, A.F.P.; Mittelmeijer-Hazeleger, M.C.; v.d. Bergh, J.; Aguado, S.; Jansen, J.C.; Rothenberg, G.; Rodrigues, A.E.; Kapteijn, F.


    We investigate the influence of the aluminium content on the adsorption of hexane isomers at 293 K on MFI type zeolites (Si/Al ratios - SAR of 25, 100 and infinity). Adsorption isotherms were assessed with a home-made volumetric system. Temporal up-take curves were recorded using a manometric set-up


    Directory of Open Access Journals (Sweden)

    Oleksandra Popova


    Full Text Available The modern context of the Ukraine-China relations presupposes high requirements to a specialist-sinologist. A rapid development of the world’s areas of science and technics alongside with corresponding transformation of the Chinese translator’s professional framework stipulate the problem of curricula contents adaptation of normative and elective disciplines comprising the speciality “Philology. Translation (the Chinese language”, those ones of work training, professiogramma based on competencies, which causes some discord with traditional training methods of the future specialists in the aforementioned field. Therefore, the aim of the pedagogical research is to describe one of the up-to-date experimental professional speech training targeted for the future translators of the Chinese language within modern educational conditions. A great attention is paid to the role of information and communications technologies in the initiated training. Thus in the course of the experiment there were determined the stages of the experimental training; they are: cognitive-enriching, operational-reproductive, creative-productive and evaluative-reflexive stages. The integral training methods (systems of exercises, forms and methods of education; profession-targeted events; their correlation with pedagogical conditions of education, etc. intended for the future translators-orientalists within the modern context of professional activity were specified. It should be mentioned that all the pedagogical conditions were implemented in an integrative way at each stage of the experimental training, which facilitated formation of the future translators-orientalists’ competencies (linguistic, communicative / speaking, translation-discursive, linguosociocultiral, specific-technological – a set of profession-targeted knowledge and skills, these competencies being components of the students’ integral translation competence which was obtained by the students

  11. Understanding the Role of Chemokines and Cytokines in Experimental Models of Herpes Simplex Keratitis

    Directory of Open Access Journals (Sweden)

    Tayaba N. Azher


    Full Text Available Herpes simplex keratitis is a disease of the cornea caused by HSV-1. It is a leading cause of corneal blindness in the world. Underlying molecular mechanism is still unknown, but experimental models have helped give a better understanding of the underlying molecular pathology. Cytokines and chemokines are small proteins released by cells that play an important proinflammatory or anti-inflammatory role in modulating the disease process. Cytokines such as IL-17, IL-6, IL-1α, and IFN-γ and chemokines such as MIP-2, MCP-1, MIP-1α, and MIP-1β have proinflammatory role in the destruction caused by HSV including neutrophil infiltration and corneal inflammation, and other chemokines and cytokines such as IL-10 and CCL3 can have a protective role. Most of the damage results from neutrophil infiltration and neovascularization. While many more studies are needed to better understand the role of these molecules in both experimental models and human corneas, current studies indicate that these molecules hold potential to be targets of future therapy.

  12. Ceruloplasmin content in blood of rats with an experimental hypertheriosis under the impact of radionuclide-contaminated territories

    International Nuclear Information System (INIS)

    Guseva, G.F.; Poplyko, M.G.; Timokhina, N.I.; Gorokh, G.A.; Klimko, N.K.


    The article presents the data on ceruloplasmin content in blood of animals with an experimental hypertheriosis under the long-term impact of Chernobyl NPP zone factors. The authors reveal the increased content of ceruloplasmin in blood of Chernobyl zone inhabiting animals with hyper- and normal function of thyroid. They regard this increased content as the manifestation of protective-compensatory reactions and the activation of the antioxidant system. Taking into consideration the combined effect of investigated factors on the increase in ceruloplasmin content, the authors mark the determining role of low-intensive irradiation. (authors)

  13. Assessing Teachers' Science Content Knowledge: A Strategy for Assessing Depth of Understanding (United States)

    McConnell, Tom J.; Parker, Joyce M.; Eberhardt, Jan


    One of the characteristics of effective science teachers is a deep understanding of science concepts. The ability to identify, explain and apply concepts is critical in designing, delivering and assessing instruction. Because some teachers have not completed extensive courses in some areas of science, especially in middle and elementary grades,…

  14. Understanding the aerosol information content in multi-spectral reflectance measurements using a synergetic retrieval algorithm

    Directory of Open Access Journals (Sweden)

    D. Martynenko


    Full Text Available An information content analysis for multi-wavelength SYNergetic AErosol Retrieval algorithm SYNAER was performed to quantify the number of independent pieces of information that can be retrieved. In particular, the capability of SYNAER to discern various aerosol types is assessed. This information content depends on the aerosol optical depth, the surface albedo spectrum and the observation geometry. The theoretical analysis is performed for a large number of scenarios with various geometries and surface albedo spectra for ocean, soil and vegetation. When the surface albedo spectrum and its accuracy is known under cloud-free conditions, reflectance measurements used in SYNAER is able to provide for 2–4° of freedom that can be attributed to retrieval parameters: aerosol optical depth, aerosol type and surface albedo.

    The focus of this work is placed on an information content analysis with emphasis to the aerosol type classification. This analysis is applied to synthetic reflectance measurements for 40 predefined aerosol mixtures of different basic components, given by sea salt, mineral dust, biomass burning and diesel aerosols, water soluble and water insoluble aerosols. The range of aerosol parameters considered through the 40 mixtures covers the natural variability of tropospheric aerosols. After the information content analysis performed in Holzer-Popp et al. (2008 there was a necessity to compare derived degrees of freedom with retrieved aerosol optical depth for different aerosol types, which is the main focus of this paper.

    The principle component analysis was used to determine the correspondence between degrees of freedom for signal in the retrieval and derived aerosol types. The main results of the analysis indicate correspondence between the major groups of the aerosol types, which are: water soluble aerosol, soot, mineral dust and sea salt and degrees of freedom in the algorithm and show the ability of the SYNAER to

  15. The everyday lives of video game developers: Experimentally understanding underlying systems/structures

    Directory of Open Access Journals (Sweden)

    Casey O'Donnell


    Full Text Available This essay examines how tensions between work and play for video game developers shape the worlds they create. The worlds of game developers, whose daily activity is linked to larger systems of experimentation and technoscientific practice, provide insights that transcend video game development work. The essay draws on ethnographic material from over 3 years of fieldwork with video game developers in the United States and India. It develops the notion of creative collaborative practice based on work in the fields of science and technology studies, game studies, and media studies. The importance of, the desire for, or the drive to understand underlying systems and structures has become fundamental to creative collaborative practice. I argue that the daily activity of game development embodies skills fundamental to creative collaborative practice and that these capabilities represent fundamental aspects of critical thought. Simultaneously, numerous interests have begun to intervene in ways that endanger these foundations of creative collaborative practice.

  16. Characterisation of acoustic energy content in an experimental combustion chamber with and without external forcing (United States)

    Webster, S.; Hardi, J.; Oschwald, M.


    The influence of injection conditions on rocket engine combustion stability is investigated for a sub-scale combustion chamber with shear coaxial injection elements and the propellant combination hydrogen-oxygen. The experimental results presented are from a series of tests conducted at subcritical and supercritical pressures for oxygen and for both ambient and cryogenic temperature hydrogen. The stability of the system is characterised by the root mean squared amplitude of dynamic combustion chamber pressure in the upper part of the acoustic spectrum relevant for high frequency combustion instabilities. Results are presented for both unforced and externally forced combustion chamber configurations. It was found that, for both the unforced and externally forced configurations, the injection velocity had the strongest influence on combustion chamber stability. Through the use of multivariate linear regression the influence of hydrogen injection temperature and hydrogen injection mass flow rate were best able to explain the variance in stability for dependence on injection velocity ratio. For unforced tests turbulent jet noise from injection was found to dominate the energy content of the signal. For the externally forced configuration a non-linear regression model was better able to predict the variance, suggesting the influence of non-linear behaviour. The response of the system to variation of injection conditions was found to be small; suggesting that the combustion chamber investigated in the experiment is highly stable.

  17. Know your data: understanding implicit usage versus explicit action in video content classification (United States)

    Yew, Jude; Shamma, David A.


    In this paper, we present a method for video category classification using only social metadata from websites like YouTube. In place of content analysis, we utilize communicative and social contexts surrounding videos as a means to determine a categorical genre, e.g. Comedy, Music. We hypothesize that video clips belonging to different genre categories would have distinct signatures and patterns that are reflected in their collected metadata. In particular, we define and describe social metadata as usage or action to aid in classification. We trained a Naive Bayes classifier to predict categories from a sample of 1,740 YouTube videos representing the top five genre categories. Using just a small number of the available metadata features, we compare the classifications produced by our Naive Bayes classifier with those provided by the uploader of that particular video. Compared to random predictions with the YouTube data (21% accurate), our classifier attained a mediocre 33% accuracy in predicting video genres. However, we found that the accuracy of our classifier significantly improves by nominal factoring of the explicit data features. By factoring the ratings of the videos in the dataset, the classifier was able to accurately predict the genres of 75% of the videos. We argue that the patterns of social activity found in the metadata are not just meaningful in their own right, but are indicative of the meaning of the shared video content. The results presented by this project represents a first step in investigating the potential meaning and significance of social metadata and its relation to the media experience.

  18. Experimental public speaking: contributions to the understanding of the serotonergic modulation of fear. (United States)

    Garcia-Leal, Cybele; Graeff, Frederico Guilherme; Del-Ben, Cristina Marta


    Public speaking is widely used as a model of experimental fear and anxiety. This review aimed to evaluate the effects of pharmacological challenges on public speaking responses and their implications for the understanding of the neurobiology of normal and pathological anxiety, specifically panic disorder. We also describe methodological features of experimental paradigms using public speaking as an inducer of fear and stress. Public speaking is a potent stressor that can provoke significant subjective and physiological responses. However, variations in the manners in which public speaking is modelled can lead to different responses that need to be considered when interpreting the results. Results from pharmacological studies with healthy volunteers submitted to simulated public speaking tests have similarities with the pharmacological responses of panic patients observed in clinical practice and panic patients differ from controls in the response to the public speaking test. These data are compatible with the Deakin and Graeff hypothesis that serotonin inhibits fear, as accessed by public speaking tasks, and that this inhibition is likely related to the actions of serotonin in the dorsal periaqueductal grey matter. Copyright © 2014 Elsevier Ltd. All rights reserved.

  19. Bringing content understanding into usability testing in complex application domains—a case study in eHealth

    DEFF Research Database (Denmark)

    Andersen, Simon Bruntse; Rasmussen, Claire Kirchert; Frøkjær, Erik


    A usability evaluation technique, Cooperative Usability Testing with Questions of Understanding (CUT with QU) intended to illuminate users’ ability to understand the content information of an application is proposed. In complex application domains as for instance the eHealth domain, this issue...... the participation of four physiotherapists and four clients in a period of 3.5 months, it was demonstrated how CUT with QU can complement conventional usability testing and provide insight into users’ challenges with understanding of a new complex eHealth application. More experiments in other complex application...... domains involving different kinds of users and evaluators are needed before we can tell whether CUT with QU is an effective usability testing technique of wider applicability. Performing CUT with QU is very demanding by drawing heavily on the evaluators’ ability to respond effectively to openings...

  20. Understanding Tropical Forest Abiotic Responses to Canopy Loss and Biomass Deposition from an Experimental Hurricane Manipulation (United States)

    Van Beusekom, A.; González, G.; Stankavitch, S.; Zimmerman, J. K.


    Understanding the nature and duration of the response of tropical forests to the extreme weather events of hurricanes is critical to understanding future forest regimes, as hurricanes are expected to increase in frequency with climate change. Here we present results from a manipulative experiment on hurricane disturbance effects in the Luquillo Experimental Forest (LEF) in Puerto Rico. The LEF is an example of a forest that would be in a frequent-hurricane region in Earth System Models (ESMs). Thus, the Canopy Trimming Experiment (CTE) was designed to study the key mechanisms behind such a forest's response after a major hurricane (category 4), and guide how repeated hurricanes might be expected to alter such ecosystems using these key mechanisms. Furthermore, with explicit forest manipulation instead of natural occurrence, it is possible to separate out which aspects of hurricane disturbance are most important to be accurately included in ESMs. Phase one of the experiments ran from 2005-2012, where it was found that short-term biotic responses of the forests were driven by canopy openness rather than by debris deposition. In phase two, running from 2014 through the present, we focus here on the abiotic changes forcing the overall response of the ecosystem. The manner in which these abiotic characteristics are disturbed and the speed at which they recover will be key to the continued existence of tropical forests under a climate with more frequent hurricane activity.

  1. The experimental autoimmune encephalomyelitis (EAE) model of MS: utility for understanding disease pathophysiology and treatment (United States)



    While no single model can exactly recapitulate all aspects of multiple sclerosis (MS), animal models are essential in understanding the induction and pathogenesis of the disease and to develop therapeutic strategies that limit disease progression and eventually lead to effective treatments for the human disease. Several different models of MS exist, but by far the best understood and most commonly used is the rodent model of experimental autoimmune encephalomyelitis (EAE). This model is typically induced by either active immunization with myelin-derived proteins or peptides in adjuvant or by passive transfer of activated myelin-specific CD4+ T lymphocytes. Mouse models are most frequently used because of the inbred genotype of laboratory mice, their rapid breeding capacity, the ease of genetic manipulation, and availability of transgenic and knockout mice to facilitate mechanistic studies. Although not all therapeutic strategies for MS have been developed in EAE, all of the current US Food and Drug Administration (FDA)-approved immunomodulatory drugs are effective to some degree in treating EAE, a strong indicator that EAE is an extremely useful model to study potential treatments for MS. Several therapies, such as glatiramer acetate (GA: Copaxone), and natalizumab (Tysabri), were tested first in the mouse model of EAE and then went on to clinical trials. Here we discuss the usefulness of the EAE model in understanding basic disease pathophysiology and developing treatments for MS as well as the potential drawbacks of this model. PMID:24507518

  2. Improved Understanding of Implosion Symmetry through New Experimental Techniques Connecting Hohlraum Dynamics with Laser Beam Deposition (United States)

    Ralph, Joseph; Salmonson, Jay; Dewald, Eduard; Bachmann, Benjamin; Edwards, John; Graziani, Frank; Hurricane, Omar; Landen, Otto; Ma, Tammy; Masse, Laurent; MacLaren, Stephen; Meezan, Nathan; Moody, John; Parrilla, Nicholas; Pino, Jesse; Sacks, Ryan; Tipton, Robert


    Understanding what affects implosion symmetry has been a challenge for scientists designing indirect drive inertial confinement fusion experiments on the National Ignition Facility (NIF). New experimental techniques and data analysis have been employed aimed at improving our understanding of the relationship between hohlraum dynamics and implosion symmetry. Thin wall imaging data allows for time-resolved imaging of 10 keV Au l-band x-rays providing for the first time on the NIF, a spatially resolved measurement of laser deposition with time. In the work described here, we combine measurements from the thin wall imaging with time resolved views of the interior of the hohlraum. The measurements presented are compared to hydrodynamic simulations as well as simplified physics models. The goal of this work is to form a physical picture that better explains the relationship of the hohlraum dynamics and capsule ablator on laser beam propagation and implosion symmetry. This work was performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under contract DE-AC52-07NA27344.

  3. Taxonomic structure and population level of colon microbial contents in white rats with experimental thyrotoxicosis

    Directory of Open Access Journals (Sweden)

    L.I. Sydorchuk


    Full Text Available Background. Production of numerous biologically active compounds and their metabolites by intestinal microflora, interaction with the immune and other systems is of great importance while studying its changes in various diseases, one of which is thyrotoxicosis. So, the purpose of this study was to determine the severity of intestine microbioma disorder in white rats with experimental thyrotoxicosis (ET. Materials and methods. Studies were carried out on 25 mature male white rats (15 — control group, 10 — research group. ET was simulated by intragastric administration of L-thyroxine for 14 days. Under sterile conditions a laparotomy was performed, a section (2–3 cm of the large intestine with its contents was taken. Sterile 0.9% NaCl solution was added to the content. Series of ten-fold dilutions with a concentration of the initial mixture of 10–2 to 10–11 was prepared. From each test tube 0.01 ml was seeded on solid nutrient media with subsequent isolation and identification of microbes according to morphological, tinctorial, cultural and biochemical properties. Results. The results of the study demonstrated that in ET animals the main microbioma is represented by bacteria Bifidobacterium, Lactobacillus, Bacteroides, and also opportunistic enterobacteria (Escherichia, Proteus, Klebsiella, peptococcus, staphylococci and clostridia. This is accompanied by the elimination of Peptostreptococcus, Enterococcus from bacterial biotope and the contamination of K. oxytoca and staphylococci. There was a pronounced deficit of bifidobacteria by 42.81 %, lactobacillus by 22.57 %, normal intestinal bacillus by 16.48 %. By the population level, the coefficient of quantitative dominance and the significance factor, the leading place is occupied by bacteroids, role of which is increased by 21.72 %, and lactobacillus role decreases by 39.31 %, bifidobacteria decreases by 51.48 % and E. coli decreases by 57.49 %. In this case, the role of peptococcus 3

  4. An Experimental and Chemical Kinetics Study of the Combustion of Syngas and High Hydrogen Content Fuels

    Energy Technology Data Exchange (ETDEWEB)

    Santoro, Robers [Pennsylvania State Univ., State College, PA (United States); Dryer, Frederick [Princeton Univ., NJ (United States); Ju, Yiguang [Princeton Univ., NJ (United States)


    An integrated and collaborative effort involving experiments and complementary chemical kinetic modeling investigated the effects of significant concentrations of water and CO2 and minor contaminant species (methane [CH4], ethane [C2H6], NOX, etc.) on the ignition and combustion of HHC fuels. The research effort specifically addressed broadening the experimental data base for ignition delay, burning rate, and oxidation kinetics at high pressures, and further refinement of chemical kinetic models so as to develop compositional specifications related to the above major and minor species. The foundation for the chemical kinetic modeling was the well validated mechanism for hydrogen and carbon monoxide developed over the last 25 years by Professor Frederick Dryer and his co-workers at Princeton University. This research furthered advance the understanding needed to develop practical guidelines for realistic composition limits and operating characteristics for HHC fuels. A suite of experiments was utilized that that involved a high-pressure laminar flow reactor, a pressure-release type high-pressure combustion chamber and a high-pressure turbulent flow reactor.

  5. Bursting strength and collagen content changes in esophageal anastomoses. Comparative experimental study in dogs. (United States)

    Kovács, T; Köves, I; Pandi, E; Németh, T; Kralovánszky, J


    The Biofragmentable Anastomosis Ring (BAR) is a mechanical device composed of absorbable material, performs an inverted anastomosis by atraumatic compression. It is a safe method recommended for bowel ends covered by serosal layer. The feasibility for esophageal surgery hasn't been proved. In our study we compared the healing of transsected intrathoracic esophagus anastomosed with BAR versus Stapler on an experimental dog model by evaluating the bursting strength (BS) and collagen (Hydroxyproline (HP)) concentration and content in different sites and defined time points after surgery (4th, 7th, 14th, 28th day). Forty-six mongrel dogs were randomly separated into two groups (28 BAR, 18 Stapler) and parameters of surgical repair evaluated after sacrification on certain days. Although we had a total of 4 leaks (14,3%) only in the BAR group (2 were clinically relevant and fatal), there was no significant difference in the leakage rate between the two groups. BS was significantly higher in the BAR group during the first week with values almost equal from the 14th day, in both groups. BS measurement reflects anastomotic strength only during the first two postoperative weeks. After this rupture is often produced outside the anastomotic line. HP concentration showed no significant differences from samples taken next to and far from the anastomotic line. The HP rate showed a significant reduction in the 4th and 7th day subgroups, and values close to the reference from the 14th day with both techniques. BS and HP changes proved a normal tissue repair with no significant difference, showing that both methods are suitable to perform anastomoses on the intrathoracic esophagus in mongrel dogs. The higher mechanical stability of the BAR anastomosis could suggest the feasibility of the method in conditions where higher mechanical strength is requested.

  6. An XAS experimental approach to study low Pt content electrocatalysts operating in PEM fuel cells. (United States)

    Principi, Emiliano; Witkowska, Agnieszka; Dsoke, Sonia; Marassi, Roberto; Di Cicco, Andrea


    We present an X-ray absorption spectroscopy (XAS) study of a low Pt content catalyst layer (Pt loading 0.1 mg cm(-2)) operating at the cathode of a proton exchange membrane fuel cell (PEMFC). This catalyst is based on the use of a mesoporous inorganic matrix as a support for the catalyst Pt nanoparticles. Due to the high Pt dilution, in situ measurements of its structural properties by XAS are challenging and suitable experimental strategies must be devised for this purpose. In particular, we show that accurate XAS in situ fluorescence measurements can be obtained using an optimized fuel cell, suitable protocols for alignment of a focused X-ray beam and an appropriate filter for the background signal of the other atomic species contained in the electrodes. Details, advantages and limitations of the XAS technique for in situ measurements are discussed. Analysis of the near-edge XAS and EXAFS (extended X-ray absorption fine structure) data, corroborated by a HRTEM (high-resolution transmission electron microscopy) study, shows that the Pt particles have a local structure compatible with that of bulk Pt (fcc) and coordination numbers match those expected for particles with typical sizes in the 1.5-2.0 nm range. Substantial changes in the oxidation state and in local atomic arrangement of the Pt particles are found for different applied potentials. The catalyst support, containing W atoms, exhibits a partial reduction upon PEMFC activation, thus mimicking the catalyst behavior. This indicates a possible role of the mesoporous matrix in favouring the oxygen reduction reaction (ORR) and stimulates further research on active catalyst supports.

  7. Experimental design to monitor the influence of crop residue management on the dynamics of soil water content (United States)

    Chélin, Marie; Hiel, Marie-Pierre; Parvin, Nargish; Bodson, Bernard; Degré, Aurore; Nguyen, Frédéric; Garré, Sarah


    Choices related to crop residue management affecting soil structure determine spatio-temporal dynamics of water content and eventually crop yields. In this contribution, we will discuss the experimental design we adopted to study the influence of agricultural management strategies (tillage and residue management) on the soil water dynamics under maize in a Cutanic Siltic Luvisol in Gembloux, Belgium. Three different treatments will be studied: a conventional ploughing realized either in December 2014 or just before sowing in April 2015, and a strip tillage in April 2015. A bare soil under conventional ploughing will also be monitored in order to better understand the influence of the plant over the growing season. In order to limit soil disturbance, we opted for the use of electrical resistivity tomography (ERT) and we use the bulk electrical conductivity as a proxy for soil moisture content. ERT will be collected every week on a surface of two square meters corresponding to three rows of seven maize plants through surface stainless steel electrodes. Five additional sticks with stainless steel electrodes will be vertically inserted into the soil up to 1.50 m to get more detailed information near to the central maize row. In each of the monitoring plots, two time-domain reflectometry (TDR) probes will be installed for data validation. In order to calibrate the relationship between electrical resistivity and soil water content under highly variable field conditions (changes in soil structure, variable weather conditions, plant growth, fertilization), a trench will be dug, in which a set of four electrodes, one TDR probe and one temperature sensor will be placed at four different depths. In addition, two suction cups will be installed in each of the plots to quantify changes in ion composition and electrical conductivity of the soil solution at two different depths. Within the framework of the multidisciplinary research platform AgricultureIsLife, regular assessment

  8. The social making of educational theory: Unraveling how to understand the content, emergence and transformation of educational theory

    DEFF Research Database (Denmark)

    Øland, Trine; Hansen, Christian Sandbjerg

    of the ideas and theories put forth by the ‘great’ philosophical-educational thinkers, which is analyzed in terms of logical-coherence and/or moral-ethical value. 2) A historical approach that place focus on the different historical individuals and their changing educational ideas or theories, often vaguely......This article concerns the question of how it is possible to study, understand and explain the content, emergence and transformation of educational theories. Based on a reading of the Danish scene we detect three main positions: 1) A philosophical approach that place focus on the content...... expressed as views, and, through detailed archival studies, analyze these as part of a realistic and contextual story of the individuals, their motives and ideas, in time. 3) Approaches that unite in their inspiration from Michel Foucault, and which analyzes educational ideas and theories not through...

  9. The social making of educational theory: Unraveling how to understand the content, emergence and transformation of educational theory

    DEFF Research Database (Denmark)

    Øland, Trine; Hansen, Christian Sandbjerg

    main manifested positions by and large ignore the use of a theoretically reflected and empirically based notion of the social conditions that play a part in the production and circulation of educational ideas and theories. Thus, in the final part of the article, we argue for a fourth position inspired...... by the so-called new sociology of knowledge, and especially the work of Pierre Bourdieu. This position excels by its effort to overcome the internal-external dichotomy that haunts the philosophical as well as the historical position and by its explanatory power drawn from a multidimensional theory of social......This article concerns the question of how it is possible to study, understand and explain the content, emergence and transformation of educational theories. Based on a reading of the Danish scene we detect three main positions: 1) A philosophical approach that place focus on the content...

  10. The woodrat gut microbiota as an experimental system for understanding microbial metabolism of dietary toxins

    Directory of Open Access Journals (Sweden)

    Kevin D. Kohl


    Full Text Available The microbial communities inhabiting the alimentary tracts of mammals, particularly those of herbivores, are estimated to be one of the densest microbial reservoirs on Earth. The significance of these gut microbes in influencing the physiology, ecology and evolution of their hosts is only beginning to be realized. To understand the microbiome of herbivores with a focus on nutritional ecology, while evaluating the roles of host evolution and environment in sculpting microbial diversity, we have developed an experimental system consisting of the microbial communities of several species of herbivorous woodrats (genus Neotoma that naturally feed on a variety of dietary toxins. We designed this system to investigate the long-standing, but experimentally neglected hypothesis that ingestion of toxic diets by herbivores is facilitated by the gut microbiota. Like several other rodent species, the woodrat stomach has a sacculated, nongastric foregut portion. We have documented a dense and diverse community of microbes in the woodrat foregut, with several genera potentially capable of degrading dietary toxins and/or playing a role in stimulating hepatic detoxification enzymes of the host. The biodiversity of these gut microbes appears to be a function of host evolution, ecological experience and diet, such that dietary toxins increase microbial diversity in hosts with experience with these toxins while novel toxins depress microbial diversity. These microbial communities are critical to the ingestion of a toxic diet as reducing the microbial community with antibiotics impairs the host’s ability to feed on dietary toxins. Furthermore, the detoxification capacity of gut microbes can be transferred from Neotoma both intra and interspecifically to naïve animals that lack ecological and evolutionary history with these toxins. In addition to advancing our knowledge of complex host-microbes interactions, this system holds promise for identifying microbes that

  11. Experimental and Modeling Approaches for Understanding the Effect of Gene Expression Noise in Biological Development

    Directory of Open Access Journals (Sweden)

    David M. Holloway


    Full Text Available Biological development involves numerous chemical and physical processes which must act in concert to reliably produce a cell, a tissue, or a body. To be successful, the developing organism must be robust to variability at many levels, such as the environment (e.g., temperature, moisture, upstream information (such as long-range positional information gradients, or intrinsic noise due to the stochastic nature of low concentration chemical kinetics. The latter is especially relevant to the regulation of gene expression in cell differentiation. The temporal stochasticity of gene expression has been studied in single celled organisms for nearly two decades, but only recently have techniques become available to gather temporally-resolved data across spatially-distributed gene expression patterns in developing multicellular organisms. These demonstrate temporal noisy “bursting” in the number of gene transcripts per cell, raising the question of how the transcript number defining a particular cell type is produced, such that one cell type can reliably be distinguished from a neighboring cell of different type along a tissue boundary. Stochastic spatio-temporal modeling of tissue-wide expression patterns can identify signatures for specific types of gene regulation, which can be used to extract regulatory mechanism information from experimental time series. This Perspective focuses on using this type of approach to study gene expression noise during the anterior-posterior segmentation of the fruit fly embryo. Advances in experimental and theoretical techniques will lead to an increasing quantification of expression noise that can be used to understand how regulatory mechanisms contribute to embryonic robustness across a range of developmental processes.

  12. The researcher as experimental subject: using self-experimentation to access experiences, understand social phenomena, and stimulate reflexivity. (United States)

    Corti, Kevin; Reddy, Geetha; Choi, Ellen; Gillespie, Alex


    The current article argues that researcher-as-subject self-experimentation can provide valuable insight and systematic knowledge to social psychologists. This approach, the modus operandi of experimental psychology when the field was in its infancy, has been largely eclipsed by an almost exclusive focus on participant-as-subject other-experimentation. Drawing from the non-experimental first-person traditions of autoethnography, participant observation, and phenomenology, we argue that participating as both observer and subject within one's own social psychological experiment affords researchers at least three potential benefits: (1) access to "social qualia," that is, the subjective experience of social phenomena; (2) improved mental models of social phenomena, potentially stimulating new research questions; and (3) an enhanced ability to be reflexive about the given experiment. To support our position, we provide first-person self-reflections from researchers who have self-experimented with transformed social interactions involving Milgram's cyranoid method. We close by offering guidelines on how one might approach self-experimentation, and discuss a variety of first-person perspective ethnographic technologies that can be incorporated into the practice.

  13. Understanding metastable phase transformation during crystallization of RDX, HMX and CL-20: experimental and DFT studies. (United States)

    Ghosh, Mrinal; Banerjee, Shaibal; Shafeeuulla Khan, Md Abdul; Sikder, Nirmala; Sikder, Arun Kanti


    Multiphase growth during crystallization severely affects deliverable output of explosive materials. Appearance and incomplete transformation of metastable phases are a major source of polymorphic impurities. This article presents a methodical and molecular level understanding of the metastable phase transformation mechanism during crystallization of cyclic nitramine explosives, viz. RDX, HMX and CL-20. Instantaneous reverse precipitation yielded metastable γ-HMX and β-CL-20 which undergo solution mediated transformation to the respective thermodynamic forms, β-HMX and ε-CL-20, following 'Ostwald's rule of stages'. However, no metastable phase, anticipated as β-RDX, was evidenced during precipitation of RDX, which rather directly yielded the thermodynamically stable α-phase. The γ→β-HMX and β→ε-CL-20 transformations took 20 and 60 minutes respectively, whereas formation of α-RDX was instantaneous. Density functional calculations were employed to identify the possible transition state conformations and to obtain activation barriers for transformations at wB97XD/6-311++G(d,p)(IEFPCM)//B3LYP/6-311G(d,p) level of theory. The computed activation barriers and lattice energies responsible for transformation of RDX, HMX and CL-20 metastable phases to thermodynamic ones conspicuously supported the experimentally observed order of phase stability. This precise result facilitated an understanding of the occurrence of a relatively more sensitive and less dense β-CL-20 phase in TNT based melt-cast explosive compositions, a persistent and critical problem unanswered in the literature. The crystalline material recovered from such compositions revealed a mixture of β- and ε-CL-20. However, similar compositions of RDX and HMX never showed any metastable phase. The relatively long stability with the highest activation barrier is believed to restrict complete β→ε-CL-20 transformation during processing. Therefore a method is suggested to overcome this issue.

  14. Understanding AlN Obtaining Through Computational Thermodynamics Combined with Experimental Investigation (United States)

    Florea, R. M.


    Basic material concept, technology and some results of studies on aluminum matrix composite with dispersive aluminum nitride reinforcement was shown. Studied composites were manufactured by „in situ” technique. Aluminum nitride (AlN) has attracted large interest recently, because of its high thermal conductivity, good dielectric properties, high flexural strength, thermal expansion coefficient matches that of Si and its non-toxic nature, as a suitable material for hybrid integrated circuit substrates. AlMg alloys are the best matrix for AlN obtaining. Al2O3-AlMg, AlN-Al2O3, and AlN-AlMg binary diagrams were thermodynamically modelled. The obtained Gibbs free energies of components, solution parameters and stoichiometric phases were used to build a thermodynamic database of AlN- Al2O3-AlMg system. Obtaining of AlN with Liquid-phase of AlMg as matrix has been studied and compared with the thermodynamic results. The secondary phase microstructure has a significant effect on the final thermal conductivity of the obtained AlN. Thermodynamic modelling of AlN-Al2O3-AlMg system provided an important basis for understanding the obtaining behavior and interpreting the experimental results.

  15. Understanding the influence of biofilm accumulation on the hydraulic properties of soils: a mechanistic approach based on experimental data (United States)

    Carles Brangarí, Albert; Sanchez-Vila, Xavier; Freixa, Anna; Romaní, Anna M.; Fernàndez-Garcia, Daniel


    The distribution, amount, and characteristics of biofilms and its components govern the capacity of soils to let water through, to transport solutes, and the reactions occurring. Therefore, unraveling the relationship between microbial dynamics and the hydraulic properties of soils is of concern for the management of natural systems and many technological applications. However, the increased complexity of both the microbial communities and the geochemical processes entailed by them causes that the phenomenon of bioclogging remains poorly understood. This highlights the need for a better understanding of the microbial components such as live and dead bacteria and extracellular polymeric substances (EPS), as well as of their spatial distribution. This work tries to shed some light on these issues, providing experimental data and a new mechanistic model that predicts the variably saturated hydraulic properties of bio-amended soils based on these data. We first present a long-term laboratory infiltration experiment that aims at studying the temporal variation of selected biogeochemical parameters along the infiltration path. The setup consists of a 120-cm-high soil tank instrumented with an array of sensors plus soil and liquid samplers. Sensors measured a wide range of parameters in continuous, such as volumetric water content, electrical conductivity, temperature, water pressure, soil suction, dissolved oxygen, and pH. Samples were kept for chemical and biological analyses. Results indicate that: i) biofilm is present at all depths, denoting the potential for deep bioclogging, ii) the redox conditions profile shows different stages, indicating that the community was adapted to changing redox conditions, iii) bacterial activity, richness and diversity also exhibit zonation with depth, and iv) the hydraulic properties of the soil experienced significant changes as biofilm proliferated. Based on experimental evidences, we propose a tool to predict changes in the

  16. Influence of HEMA content on the mechanical and bonding properties of experimental HEMA-added glass ionomer cements

    Directory of Open Access Journals (Sweden)

    Ho-Nam Lim


    Full Text Available The purpose of this study was to determine the influence of incrementally added uncured HEMA in experimental HEMA-added glass ionomer cement (HAGICs on the mechanical and shear bond strength (SBS of these materials. Increasing contents of uncured HEMA (10-50 wt.% were added to a commercial glass ionomer cement liquid (Fuji II, GC, Japan, and the compressive and diametral tensile strengths of the resulting HAGICs were measured. The SBS to non-precious alloy, precious alloy, enamel and dentin was also determined after these surfaces were subjected to either airborne-particle abrasion (Aa or SiC abrasive paper grinding (Sp. Both strength properties of the HAGICs first increased and then decreased as the HEMA content increased, with a maximum value obtained when the HEMA content was 20% for the compressive strength and 40% for the tensile strength. The SBS was influenced by the HEMA content, the surface treatment, and the type of bonding surface (p<0.05. These results suggest that addition of an appropriate amount of HEMA to glass ionomer cement would increase diametral tensile strength as well as bond strength to alloys and teeth. These results also confirm that the optimal HEMA content ranged from 20 to 40% within the limitations of this experimental condition.

  17. Exploring one aspect of pedagogical content knowledge of teaching assistants using the test of understanding graphs in kinematics

    Directory of Open Access Journals (Sweden)

    Alexandru Maries


    Full Text Available The Test of Understanding Graphs in Kinematics (TUG-K is a multiple-choice test developed by Beichner in 1994 to assess students’ understanding of kinematics graphs. Many of the items on the TUG-K have strong distractor choices which correspond to students’ common difficulties with kinematics graphs. Instruction is unlikely to be effective if instructors do not know the common difficulties of introductory physics students and explicitly take them into account in their instructional design. We evaluate one aspect of the pedagogical content knowledge of first-year physics graduate students enrolled in a teaching assistant training course related to topics covered in the TUG-K. In particular, for each item on the TUG-K, the graduate students were asked to identify which incorrect answer choice they thought would be most commonly selected by introductory physics students if they did not know the correct answer after instruction in relevant concepts. We used the graduate student data and the data from Beichner’s original paper for introductory physics students (which was collected from over 500 college and high school students to assess this aspect of the pedagogical content knowledge of the graduate students, i.e., knowledge of student difficulties related to kinematics graphs as they are revealed by the TUG-K. We find that, although the graduate students, on average, performed better than random guessing at identifying introductory student difficulties on the TUG-K, they did not identify many common difficulties that introductory students have with graphs in kinematics. In addition, we find that the ability of graduate students to identify the difficulties of introductory students is context dependent and that discussions among the graduate students improved their understanding of student difficulties related to kinematics graphs. Moreover, we find that the ability of American graduate students in identifying common student difficulties is

  18. Understanding the role of representations of human-leopard conflict in Mumbai through media-content analysis. (United States)

    Bhatia, Saloni; Athreya, Vidya; Grenyer, Richard; MacDonald, David W


    Attempts to minimize the effects of human-wildlife conflict (HWC) on conservation goals require an understanding of the mechanisms by which such conflicts are caused and sustained. This necessitates looking beyond the natural sciences to the human dimensions of wildlife management. Public dissemination of information regarding HWC occurs largely through the mass media. We conducted a content analysis of print media articles on human-leopard conflict in Mumbai, India. We sought to understand the framing of HWC and the changes in media coverage over a 10-year period (2001-2011) during which a large number of attacks on people prior to 2005 were followed by a program of trapping and relocation. After 2005, when there was a decrease in the level of conflict, the tone of English-language media reports changed. The perpetrator framing was over 5 times more likely before 2005, whereas a neutral framing was twice as likely after 2005. English-language and non-English-language print media differed significantly in their framing of HWC and in the kinds of solutions advocated. Our results also suggest the print mass media in Mumbai could be an influential conduit for content that diminishes HWC. These media outlets seem attentive to human-leopard conflict, capable of correcting erroneous perceptions and facilitating mitigation and effective management. We believe better contact and mutual understanding between conservation professionals and the mass media could be an important component of managing HWC. We further suggest that in such interactions conservation professionals need to be aware of cultural and linguistic differences in reporting within the country. © 2013 Society for Conservation Biology.

  19. Computational and experimental platform for understanding and optimizing water flux and salt rejection in nanoporous membranes.

    Energy Technology Data Exchange (ETDEWEB)

    Rempe, Susan B.


    Affordable clean water is both a global and a national security issue as lack of it can cause death, disease, and international tension. Furthermore, efficient water filtration reduces the demand for energy, another national issue. The best current solution to clean water lies in reverse osmosis (RO) membranes that remove salts from water with applied pressure, but widely used polymeric membrane technology is energy intensive and produces water depleted in useful electrolytes. Furthermore incremental improvements, based on engineering solutions rather than new materials, have yielded only modest gains in performance over the last 25 years. We have pursued a creative and innovative new approach to membrane design and development for cheap desalination membranes by approaching the problem at the molecular level of pore design. Our inspiration comes from natural biological channels, which permit faster water transport than current reverse osmosis membranes and selectively pass healthy ions. Aiming for an order-of-magnitude improvement over mature polymer technology carries significant inherent risks. The success of our fundamental research effort lies in our exploiting, extending, and integrating recent advances by our team in theory, modeling, nano-fabrication and platform development. A combined theoretical and experimental platform has been developed to understand the interplay between water flux and ion rejection in precisely-defined nano-channels. Our innovative functionalization of solid state nanoporous membranes with organic protein-mimetic polymers achieves 3-fold improvement in water flux over commercial RO membranes and has yielded a pending patent and industrial interest. Our success has generated useful contributions to energy storage, nanoscience, and membrane technology research and development important for national health and prosperity.

  20. The magnesium content in jaws and teeth of rats with experimental caries

    International Nuclear Information System (INIS)

    Djulgerova, E.; Bakyrdshiev, P.; Kuleff, I.; Apostolov, D.


    The content of Mg is determined in the teeth and maxillary bones of rats by instrumental neutron activation analysis (INAA). The rats are fed with carbohydrate diet to which MgCl 2 , NaF and methylene blue are added. An opposite influence of F ions and methylene blue on magnesium content in bones and teeth is found, while both additives reduce the caries. (author)

  1. Comparative experimental investigation on the actuation mechanisms of ionic polymer–metal composites with different backbones and water contents

    Energy Technology Data Exchange (ETDEWEB)

    Zhu, Zicai; Chang, Longfei; Wang, Yanjie; Chen, Hualing, E-mail: [State Key Laboratory of Mechanical Structure Strength and Vibration, Xi' an Jiaotong University, Xi' an 710049 (China); School of Mechanical Engineering, Xi' an Jiaotong University, Xi' an 710049 (China); Asaka, Kinji [Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Ikeda, Osaka 563-8577 (Japan); Zhao, Hongxia [Niumag Corporation, Shanghai 200333 (China); Li, Dichen [School of Mechanical Engineering, Xi' an Jiaotong University, Xi' an 710049 (China); State Key Laboratory for Manufacturing Systems Engineering, Xi' an Jiaotong University, Xi' an 710049 (China)


    Water-based ionic polymer–metal composites (IPMCs) exhibit complex deformation properties, especially when the water content changes. To explore the general actuation mechanisms, both Nafion and Flemion membranes are used as the polymer backbones. IPMC deformation includes three stages: fast anode deformation, relaxation deformation, and slow anode deformation, which is mainly dependent on the water content and the backbone. When the water content decreases from 21 to 14 wt. %, Nafion–IPMC exhibits a large negative relaxation deformation, zero deformation, a positive relaxation deformation, and a positive steady deformation without relaxation in sequence. Despite the slow anode deformation, Flemion–IPMC also shows a slight relaxation deformation, which disappears when the water content is less than 13 wt. %. The different water states are investigated at different water contents using nuclear magnetic resonance spectroscopy. The free water, which decreases rapidly at the beginning through evaporation, is proven to be critical for relaxation deformation. For the backbone, indirect evidence from the steady current response is correlated with the slow anode deformation of Flemion-IPMC. The latter is explained by the secondary dissociation of the weak acid group –COOH. Finally, we thoroughly explain not only the three deformations by swelling but also their evolvement with decreasing water content. A fitting model is also presented based on a multi-diffusion equation to reveal the deformation processes more clearly, the results from which are in good agreement with the experimental results.

  2. A regional distributed hydrological modelling approach for flash-flood understanding and experimental design (United States)

    Braud, Isabelle; Anquetin, Sandrine; Roux, Hélène; Vannier, Olivier; Maubourguet, Marie-Madeleine; Viallet, Pierre; Boudevillain, Brice; Dartus, Denis; Creutin, Jean-Dominique


    resolution spatial and temporal data are required in order to properly simulate peak discharge and flow dynamics for a range of scales. The river bed roughness also influences the peak intensity and time. Soil spatial representation is shown to have a significant role on runoff coefficients and on the spatial variability of saturation dynamics. For some catchments, the impact of soil properties on the simulated discharges was of the same order of magnitude as the impact of the rainfall estimation. The results were very similar for the two distributed models, despite their difference in structure. They show that the poor knowledge of soil properties, mainly soil depth, initial soil water content and saturated hydraulic conductivity is detrimental to robust estimation of discharge. A better knowledge of these variables is therefore recommended. In particular soil depth is required. Post field estimation of peak discharge were very valuable for the regional assessment of the methodology, but must be complemented with data of the whole hydrographs to reduce the uncertainty in flow dynamics and runoff production. Effort towards improved quantitative rainfall estimation using a network of radars must also be continued. The results of the study are used in the design of the future HyMeX experiment, aiming at improving the Mediterranean water balance and the knowledge of extreme events. A strategy based on gauged nested catchments is set up. Detailed measurements of the water balance (discharge, soil moisture, evapotranspiration) are proposed on small catchments of about 1 km2 in order to improve the process understanding. An intermediate scale is defined for catchments of about 100 km2 with distributed hydrometry, based on Large Scale Image Velocimetry to tackle the change of scale problem. Finally, operational data are used at larger scale of about 1000 km2. These data will also be useful to propose improved modelling tools applicable on ungauged catchments.

  3. Understanding the usage of content in a mental health intervention for depression: an analysis of log data. (United States)

    Van Gemert-Pijnen, Julia Ewc; Kelders, Saskia M; Bohlmeijer, Ernst T


    Web-based interventions for the early treatment of depressive symptoms can be considered effective in reducing mental complaints. However, there is a limited understanding of which elements in an intervention contribute to effectiveness. For efficiency and effectiveness of interventions, insight is needed into the use of content and persuasive features. The aims of this study were (1) to illustrate how log data can be used to understand the uptake of the content of a Web-based intervention that is based on the acceptance and commitment therapy (ACT) and (2) to discover how log data can be of value for improving the incorporation of content in Web-based interventions. Data from 206 participants (out of the 239) who started the first nine lessons of the Web-based intervention, Living to the Full, were used for a secondary analysis of a subset of the log data of the parent study about adherence to the intervention. The log files used in this study were per lesson: login, start mindfulness, download mindfulness, view success story, view feedback message, start multimedia, turn on text-message coach, turn off text-message coach, and view text message. Differences in usage between lessons were explored with repeated measures ANOVAs (analysis of variance). Differences between groups were explored with one-way ANOVAs. To explore the possible predictive value of the login per lesson quartiles on the outcome measures, four linear regressions were used with login quartiles as predictor and with the outcome measures (Center for Epidemiologic Studies-Depression [CES-D] and the Hospital Anxiety and Depression Scale-Anxiety [HADS-A] on post-intervention and follow-up) as dependent variables. A significant decrease in logins and in the use of content and persuasive features over time was observed. The usage of features varied significantly during the treatment process. The usage of persuasive features increased during the third part of the ACT (commitment to value-based living

  4. Sulfuration resistance of five experimental Ag-Pd-Au-Cu alloys with low Pd content of 10 or 12%. (United States)

    Saitoh, Setsuo; Araki, Yoshima; Taira, Masayuki


    Commercial Ag-based alloy (46Ag-20Pd-12Au-20Cu alloy) is widely used in Japan as a casting alloy. As opposed to the commercial composition, we prepared five experimental Ag-based alloys with reduced Pd content of 10 or 12%, increased Au content of 20 to 30%, and reduced Cu content of 12 to 20%. We then evaluated their sulfuration resistance by analyzing cast specimen surfaces dipped in 0.1% Na2S solution with SEM/EPMA, TF-XRD, and XPS. It became evident that all alloys were susceptible to sulfuration in the segregated Ag-rich Pd-poor phases. The degree and speed of sulfuration, however, differed among the six alloys examined. In particular, one experimental alloy (46Ag-10Pd-30Au-12Cu) possessed a sulfuration resistance equal or superior to that of commercial Ag-based alloy, while the other four experimental alloys were inferior in sulfuration resistance. Based on the results of this study, we concluded that our newly developed 46Ag-10Pd-30Au-12Cu alloy could be employed as a new sulfuration-resistant Ag-based casting alloy--which is especially useful if the price of Pd is skyrocketing again.

  5. A review of experimental understanding of forced convection heat transfer by supercritical helium 4 flowing in ducts

    International Nuclear Information System (INIS)

    Kasao, D.; Ito, T.


    In this paper a survey of experimental understandings of steady forced convection heat transfer by supercritical helium 4 flowing in ducts is given, and the deterioration of heat transfer, the influences of buoyancy force and correlations of heat transfer are to be discussed as well

  6. Novel Experimental, Theoretical, and Calculational Approaches to Understanding the Detonation of Explosives

    National Research Council Canada - National Science Library

    Eckhardt, Craig


    Report of results of research on the initial stage of detonation is made. Experimental results involve location of a heretofore undetected intramolecular mode in RDX and confirmation of prior findings on the Raman scattering of HMX...

  7. Experimental Study on Artificial Cemented Sand Prepared with Ordinary Portland Cement with Different Contents. (United States)

    Li, Dongliang; Liu, Xinrong; Liu, Xianshan


    Artificial cemented sand test samples were prepared by using ordinary Portland cement (OPC) as the cementing agent. Through uniaxial compression tests and consolidated drained triaxial compression tests, the stress-strain curves of the artificial cemented sand with different cementing agent contents (0.01, 0.03, 0.05 and 0.08) under various confining pressures (0.00 MPa, 0.25 MPa, 0.50 MPa and 1.00 MPa) were obtained. Based on the test results, the effect of the cementing agent content ( C v ) on the physical and mechanical properties of the artificial cemented sand were analyzed and the Mohr-Coulomb strength theory was modified by using C v . The research reveals that when C v is high (e.g., C v = 0.03, 0.05 or 0.08), the stress-strain curves of the samples indicate a strain softening behavior; under the same confining pressure, as C v increases, both the peak strength and residual strength of the samples show a significant increase. When C v is low (e.g., C v = 0.01), the stress-strain curves of the samples indicate strain hardening behavior. From the test data, a function of C v (the cementing agent content) with c ' (the cohesion force of the sample) and Δϕ' (the increment of the angle of shearing resistance) is obtained. Furthermore, through modification of the Mohr-Coulomb strength theory, the effect of cementing agent content on the strength of the cemented sand is demonstrated.

  8. Experimental Study on Artificial Cemented Sand Prepared with Ordinary Portland Cement with Different Contents

    Directory of Open Access Journals (Sweden)

    Dongliang Li


    Full Text Available Artificial cemented sand test samples were prepared by using ordinary Portland cement (OPC as the cementing agent. Through uniaxial compression tests and consolidated drained triaxial compression tests, the stress-strain curves of the artificial cemented sand with different cementing agent contents (0.01, 0.03, 0.05 and 0.08 under various confining pressures (0.00 MPa, 0.25 MPa, 0.50 MPa and 1.00 MPa were obtained. Based on the test results, the effect of the cementing agent content (Cv on the physical and mechanical properties of the artificial cemented sand were analyzed and the Mohr-Coulomb strength theory was modified by using Cv. The research reveals that when Cv is high (e.g., Cv = 0.03, 0.05 or 0.08, the stress-strain curves of the samples indicate a strain softening behavior; under the same confining pressure, as Cv increases, both the peak strength and residual strength of the samples show a significant increase. When Cv is low (e.g., Cv = 0.01, the stress-strain curves of the samples indicate strain hardening behavior. From the test data, a function of Cv (the cementing agent content with c′ (the cohesion force of the sample and Δϕ′ (the increment of the angle of shearing resistance is obtained. Furthermore, through modification of the Mohr-Coulomb strength theory, the effect of cementing agent content on the strength of the cemented sand is demonstrated.

  9. Experimental Paper. Intrapopulation variability of flavonoid content in roots of Baikal skullcap (Scutellaria baicalensis Georgi

    Directory of Open Access Journals (Sweden)

    Kosakowska Olga


    Full Text Available Introduction: Baikal skullcap (Scutellaria baicalensis Georgi is an important medicinal plant, indigenous to Asia. Due to a wide range of pharmacological activities, its roots has been used for ages in Traditional Chinese Medicine. Recently, the species has become an object of interest of Western medicine, as well. Objective: The aim of the study was to determine the variability of Baikal skullcap population originated from Mongolia and cultivated in Poland, in terms of content and composition of flavonoids in the roots. Methods: The objects of the study were 15 individual plants, selected within examined population and cloned in order to obtain a sufficient amount of raw material. The total content of flavonoids in roots was determined according to Polish Pharmacopeia 6th. The qualitative analysis of flavonoids was carried out using HPLC, Shimadzu chromatograph. Results: The dry mass of roots ranged from 25.88 to 56.14 g × plant-1. The total content of flavonoids (expressed as a quercetin equivalent varied between 0.17 and 0.52% dry matter (DM. Nine compounds were detected within the group, with oroxylin A 7-Oglucuronide (346.90-1063.00 mg × 100 g-1 DM as a dominant, which differentiated investigated clones at the highest degree (CV=0.27. Baicalin (391.40-942.00 mg × 100 g-1 DM, wogonoside (324.00-641.10 mg × 100 g-1 DM and hesperetine 7-O-glucoside (163.00-346.32 mg × 100 g-1 DM were also present in a considerable amounts. Clone 7 was distinguished by the highest content of all investigated compounds, except wogonin and oroxylin A 7-O-glucuronide. Conclusions: Results obtained in present study show a high variability within Baical skullcap investigated population in respect of flavonoid compounds detected in roots. Thus, the results may be used in future investigations concerning the selection and breeding of this species.

  10. Experimental investigations on heat content of supercooled sodium acetate trihydrate by a simple heat loss method

    DEFF Research Database (Denmark)

    Kong, Weiqiang; Dannemand, Mark; Johansen, Jakob Berg


    experimentally investigated by a simple heat loss method. The aim was to find compositions of maximum heat released from the crystallization of supercooled sodium acetate trihydrate samples at ambient temperature. It was found that samples of sodium acetate trihydrate with 0.5–2% (wt.%) Carboxy-Methyl Cellulose...

  11. ShapeShop: Towards Understanding Deep Learning Representations via Interactive Experimentation. (United States)

    Hohman, Fred; Hodas, Nathan; Chau, Duen Horng


    Deep learning is the driving force behind many recent technologies; however, deep neural networks are often viewed as "black-boxes" due to their internal complexity that is hard to understand. Little research focuses on helping people explore and understand the relationship between a user's data and the learned representations in deep learning models. We present our ongoing work, ShapeShop, an interactive system for visualizing and understanding what semantics a neural network model has learned. Built using standard web technologies, ShapeShop allows users to experiment with and compare deep learning models to help explore the robustness of image classifiers.

  12. ShapeShop: Towards Understanding Deep Learning Representations via Interactive Experimentation

    Energy Technology Data Exchange (ETDEWEB)

    Hohman, Frederick M.; Hodas, Nathan O.; Chau, Duen Horng


    Deep learning is the driving force behind many recent technologies; however, deep neural networks are often viewed as “black-boxes” due to their internal complexity that is hard to understand. Little research focuses on helping people explore and understand the relationship between a user’s data and the learned representations in deep learning models. We present our ongoing work, ShapeShop, an interactive system for visualizing and understanding what semantics a neural network model has learned. Built using standard web technologies, ShapeShop allows users to experiment with and compare deep learning models to help explore the robustness of image classifiers.

  13. Understanding flocculation mechanism of graphene oxide for organic dyes from water: Experimental and molecular dynamics simulation

    Directory of Open Access Journals (Sweden)

    Jun Liu


    Full Text Available Flocculation treatment processes play an important role in water and wastewater pretreatment. Here we investigate experimentally and theoretically the possibility of using graphene oxide (GO as a flocculant to remove methylene blue (MB from water. Experimental results show that GO can remove almost all MB from aqueous solutions at its optimal dosages and molecular dynamics simulations indicate that MB cations quickly congregate around GO in water. Furthermore, PIXEL energy contribution analysis reveals that most of the strong interactions between GO and MB are of a van der Waals (London dispersion character. These results offer new insights for shedding light on the molecular mechanism of interaction between GO and organic pollutants.

  14. Historic and Ethnic Music Found to Increase Geographic Understanding: A Quasi-Experimental Study (United States)

    Richardson, Ronald; Brouillette, Liane


    This article summarizes a quasi-experimental study, which demonstrated that integration of historic and ethnic music into the American history curriculum may lead to increased knowledge of the cultural and physical geography of the United States as well as enhanced student engagement. An experiment (n = 215) conducted with eighth grade students…

  15. Social network ties beyond nonredundancy: an experimental investigation of the effect of knowledge content and tie strength on creativity. (United States)

    Perry-Smith, Jill E


    Social network research emphasizes the access to nonredundant knowledge content that network ties provide. I suggest that some content is more beneficial than others and that tie strength may affect creativity for reasons other than the associated structure. That is, tie strength may affect how individuals process nonredundant knowledge. I investigate 2 types of knowledge content--information (i.e., facts or data) and frames (i.e., interpretations or impressions)--and explore whether tie strength influences their effect on creativity. Drawing on creativity theory, I employ an experimental design to provide greater theoretical clarity and to isolate causality. According to the results from 2 studies, distinct frames received from contacts facilitate creativity, but the effect of distinct information is more complex. When individuals receive distinct information from strong ties, it constrains creativity compared to distinct frames. Content from weak ties appears to facilitate creativity across all scenarios. The results of mediated moderation analysis indicate the effect of framing versus information for strong ties is driven by decision-making time, as an indicator of cognitive expansion. PsycINFO Database Record (c) 2014 APA, all rights reserved.

  16. Sampling depth of soil moisture content by radiometric measurement at 21 cm wavelength: some experimental results

    International Nuclear Information System (INIS)

    Pampaloni, P.; Paloscia, S.; Chiarantini, L.; Coppo, P.; Gagliani, S.; Luzi, G.


    The thickness of soil layer, through which moisture can be directly estimated by means of a microwave radiometer, has been investigated experimentally on a test area in Central Italy by means of airborne sensors. Aircraft remote sensing data, collected on agricultural bare and vegetated fields during the growth stage of vegetation (May-July 1988), have shown that L band microwave emission is correlated to the average moisture of the first 20 cm of soil under the surface. However, correlation between moisture at difference depths makes the identification of the actual sampling depth difficult

  17. Improving uptake and engagement with child body image interventions delivered to mothers: Understanding mother and daughter preferences for intervention content. (United States)

    Garbett, Kirsty M; Diedrichs, Phillippa C


    Mothers are a key influence on adolescent girls' body image. This study aimed to improve understanding of mothers' and daughters' preferences for content in body image interventions designed to assist mothers to promote positive body image among their daughters. British mother-daughter dyads (N=190) viewed descriptions of five evidence-based influences on body image (family, friends, and relationships; appearance-based teasing; media and celebrities; appearance conversations; body acceptance and care). Mothers and daughters each selected the two most important influences to learn about in these interventions. Overall, both mothers and daughters most frequently opted for family, friends, and relationships and body acceptance and care, whereas media and celebrities was their least preferred topic. While the overall sample of mothers and daughters agreed on preferences, Fisher's exact tests showed that within-dyad agreement was low. Recommendations for improving parent and child engagement with, and effectiveness of, child body image interventions delivered to parents are discussed. Copyright © 2016 Elsevier Ltd. All rights reserved.

  18. Experimental study on spectral absorbance in fog as a function of temperature, liquid water content, and particle size (United States)

    Mäyrä, A.; Hietala, E.; Kutila, M.; Pyykönen, P.; Tiihonen, M.; Jokela, T.


    The ECSEL joint undertaking RobustSENSE1 focuses on technologies and solutions for automated driving in adverse weather conditions. One of the main technology challenges is to improve laser scanner performance in fog where the existing 905 nm lidar reliability degrades below tolerances. This report briefly summarizes the results of experimental fog absorbance measurements, which were conducted in VTT icing wind tunnel located in VTT's premises. The content of the presentation will focus on spectral absorbance measurements in artificial fog in near infrared band.

  19. Blending Physical and Virtual Manipulatives: An Effort to Improve Students' Conceptual Understanding through Science Laboratory Experimentation (United States)

    Olympiou, Georgios; Zacharia, Zacharias C.


    This study aimed to investigate the effect of experimenting with physical manipulatives (PM), virtual manipulatives (VM), and a blended combination of PM and VM on undergraduate students' understanding of concepts in the domain of "Light and Color." A pre-post comparison study design was used for the purposes of this study that involved 70…

  20. Understanding Scientific Methodology in the Historical and Experimental Sciences via Language Analysis (United States)

    Dodick, Jeff; Argamon, Shlomo; Chase, Paul


    A key focus of current science education reforms involves developing inquiry-based learning materials. However, without an understanding of how working scientists actually "do" science, such learning materials cannot be properly developed. Until now, research on scientific reasoning has focused on cognitive studies of individual scientific fields.…

  1. Understanding Complexity and Self-Organization in a Defense Program Management Organization (Experimental Design) (United States)


    and the interrelationship with the social bureaucratic influences . Experimental Research Design The Joint Tactical Radio System (JTRS) is a family...initiatives such as the Packard Commission study, Goldwater-Nichols Legislation, and more recently, the Better Buying Power initiative. While the DoD...potential communications pathways in an organizational structure) Self-Organizing Network Behavior The nodes in the network are specific individuals

  2. 235U Prompt Fission Neutron Spectra - Experimental Mistakes or Lack of Understanding?

    International Nuclear Information System (INIS)

    Kornilov, N.


    235 U is the most important isotope for various nuclear applications. The Prompt Fission Neutron Spectrum (PFNS) from the 235 U(n,f) reaction has been investigated in many experiments at different incident neutron energies from thermal to the fast region. The different types of experiments microscopic (differential) and macroscopic (integral average cross section at thermal energy and K eff experiments) are applied for estimation of the PFNS shape. The analysis and evaluation of the microscopic data measured in the past century in the energy range 0-5 MeV can be found. The general conclusion is that the PFNS can be described reasonably well in the frame of traditional theoretical model or with its modification or with semi-empirical systematic. At the same time a continuing conflict still exists at thermal neutron energy. Microscopic experimental PFNS can not describe macroscopic data. The subgroup of NEA OECD analyzing all available experimental data concluded: ' calculated thermal spectrum has been found that simultaneously reproduces either of the two modern thermal differential measurement and the set of measured integral cross-sections to within an acceptable level'. I would like to highlight that this is a long standing conflict. It exists from the first to the last publications and is not resolved yet. The traditional arguments used by evaluators 'this is due to experimental mistakes of the microscopic data' may construct non physical 'zig-zag' dependence of the average energy of the PFNS only. This conclusion does not agree with previous analysis of the microscopic data and recent experiments. The experimental facts which can not be explained in the frame of traditional theoretical model are collected and discussed

  3. Real life experimental determination of platinum group metals content in automotive catalytic converters (United States)

    Yakoumis, I.; Moschovi, A. M.; Giannopoulou, I.; Panias, D.


    The real life experimental protocol for the preparation of spent automobile catalyst samples for elemental analysis is thoroughly described in the following study. Collection, sorting and dismantling, homogenization and sample preparation for X-Ray fluorescence spectroscopy and Atomic Adsorption Spectroscopy combined with Inductive coupled plasma mass spectrometry are discussed in detail for both ceramic and metallic spent catalysts. The concentrations of Platinum Group Metals (PGMs) in spent catalytic converters are presented based on typical consignments of recycled converters (more than 45,000 pieces) from the Greek Market. The conclusions clearly denoted commercial metallic catalytic foil contains higher PGMs loading than ceramic honeycombs. On the other hand, the total PGMs loading in spent ceramic catalytic converters has been found higher than the corresponding value for the metallic ones.


    Fernandez, Oscar Orlando Araya; Pereira, José Aires; Campos, Fábio Guilherme; Araya, Carolina Mardegan; Marinho, Gabriele Escocia; Novo, Rafaela de Souza; Oliveira, Thais Silva de; Franceschi, Yara Tinoco; Martinez, Carlos Augusto Real


    The effects of topical application of sucralfate (SCF) on the tissue content of MUC-2 protein have not yet been evaluated in experimental models of diversion colitis. To measure the tissue content of MUC-2 protein in the colonic mucosa diverted from fecal stream submitted to the SCF intervention. Thirty-six rats underwent derivation of intestinal transit through proximal colostomy and distal mucous fistula. The animals were divided into three groups which were submitted application of enemas with saline, SCF 1 g/kg/day and SCF 2 g/kg/day. Each group was divided into two subgroups, according to euthanasia was done after two or four weeks. The colitis diagnosis was established by histopathological study and the inflammatory intensity was evaluated by previously validated scale. The MUC-2 protein was identified by immunohistochemistry and the tissue content was measured computerized morphometry). The application of enemas with SCF in the concentration of 2 g/kg/day reduced inflammatory score of the segments that were diverted from fecal stream. The content of MUC-2 in diverted colon of the animals submitted to the intervention with SCF, independently of intervention period and the used concentration, was significantly greater than animals submitted to the application of enemas containing saline (papplication containing SCF at concentration of 1.0 g/kg/day (papplication of enemas containing SCF reduces the inflammatory score and avoids the reduction of tissue content of MUC-2, suggesting that the substance is a valid therapeutic strategy to preserve the mucus layer that covers the intestinal epithelium.

  5. Understanding Health Care Social Media Use From Different Stakeholder Perspectives: A Content Analysis of an Online Health Community. (United States)

    Lu, Yingjie; Wu, Yang; Liu, Jingfang; Li, Jia; Zhang, Pengzhu


    Health care social media used for health information exchange and emotional communication involves different types of users, including patients, caregivers, and health professionals. However, it is difficult to identify different stakeholders because user identification data are lacking due to privacy protection and proprietary interests. Therefore, identifying the concerns of different stakeholders and how they use health care social media when confronted with huge amounts of health-related messages posted by users is a critical problem. We aimed to develop a new content analysis method using text mining techniques applied in health care social media to (1) identify different health care stakeholders, (2) determine hot topics of concern, and (3) measure sentiment expression by different stakeholders. We collected 138,161 messages posted by 39,606 members in lung cancer, diabetes, and breast cancer forums in the online community over 10 years (January 2007 to October 2016) as experimental data. We used text mining techniques to process text data to identify different stakeholders and determine health-related hot topics, and then analyzed sentiment expression. We identified 3 significantly different stakeholder groups using expectation maximization clustering (3 performance metrics: Rand=0.802, Jaccard=0.393, Fowlkes-Mallows=0.537; Panalysis showed that patients and caregivers gradually changed their emotional state in a positive direction. The hot topics of interest and sentiment expression differed significantly among different stakeholders in different disease forums. These findings could help improve social media services to facilitate diverse stakeholder engagement for health information sharing and social interaction more effectively. ©Yingjie Lu, Yang Wu, Jingfang Liu, Jia Li, Pengzhu Zhang. Originally published in the Journal of Medical Internet Research (, 07.04.2017.

  6. Experimental study on the hydroxyproline content of enteroanastomoses established in irradiated intestines of rats

    International Nuclear Information System (INIS)

    Winter, S.


    Cross-bred Sprague-Dawley rats were subjected to percutaneous X-irradiation of the rectosigmoid using a split-dose regimen and focal dose of 50 Gy. One day as well as one, two and four months after the cessation of irradiation a termino-terminal anastomosis was established in the area exposed to radiation. On days, 3, 7, 14 and 21 after surgery those parts of the intestine, which had been united by anastomosis, were removed in order to determine the hydroxyproline content of the latter. Further determinations were made in specimens of the tissue 1 cm above the anastomosis and carried out before surgery, after intraperitoneal injection of the anaesthetic alone or in animals subjected to laparatomy including intestinal exposure, where no anastomosis was established. In general, the collagen levels determined in colon anastomoses of irradiated or non-irradiated intestines of rats did not point to any adverse effects from radiation on the healing process. This result appears to be largely consistent with the experiences so far gained at the clinical level in the preoperative irradiation of colon carcinomas. (orig./MG) [de

  7. Another quasi-experimental study of understanding/appreciation of editorial satire. (United States)

    Gruner, C R; Gruner, M W; Travillion, L J


    College students completed a 17-item scale measuring the "propensity to argue controversial topics" and 7 other nominal-scale independent variables. They then read three editorial satires and checked which of five statements was the intended thesis of each satire's author. They also rated each satire on interestingness and funniness. Analysis indicated dependence between understanding of satire and sex and regular readership of "The Far Side."

  8. N2C2M2 Experimentation and Validation: Understanding Its C2 Approaches and Implications (United States)


    the organization and execution of the experiments, specifically, Col. Fernando Freire , LtCol. António Flambó, LtCol. José Martins, LtCol. Paulo ...of ELICIT Experimental Data. Paper presented at the 13th ICCRTS, Seattle, USA, 2008. [13.] Manso, Marco, and Paulo Nunes. ELICIT and the Future C2...detailed mapping between C2 CRM variables and ELICIT refer to: MANSO, Marco, and Paulo NUNES. ELICIT and the Future C2: Theoretical Foundations for the

  9. Optimal experimental designs in RPLC at variable solvent content and pH based on prediction error surfaces. (United States)

    Torres-Lapasió, J R; Pous-Torres, S; Baeza-Baeza, J J; García-Álvarez-Coque, M C


    When pH is used as factor in reversed-phase liquid chromatographic (RPLC) separations, the need for providing quality and informative data with the minimal experimental effort becomes imperative. The most rational way to achieve this is by means of experimental designs. The interest in finding optimal designs involving solvent content and pH in RPLC is considerable, since these factors allow large variations in selectivity when ionisable compounds are involved. Unfortunately, the equations that describe the retention of these compounds with pH are nonlinear. As a consequence, factorial and other designs based on geometrical considerations are not well suited, whereas D-optimal and related designs can only be applied in an iterative fashion. In this work, an extension of G-optimal designs, aimed to enhance the quality of the predictions, is examined for problems involving solvent content and pH. The study was carried out with a set of probe ionisable compounds, for which information on retention behaviour was accurately known. A stepwise strategy was used to obtain a rapid estimation of the best design with a given number of experiments. The objective of the study was to investigate the distribution and number of points in the ideal design for compounds of different acid-base behaviour, and the possibility of finding common designs for groups of compounds. A further goal was to derive design construction rules containing the information requirements, without needing any further mathematical treatment.

  10. Experimental determination of liquidus H2O contents of haplogranite at deep-crustal conditions (United States)

    Makhluf, A. R.; Newton, R. C.; Manning, C. E.


    The liquidus water content of a haplogranite melt at high pressure ( P) and temperature ( T) is important, because it is a key parameter for constraining the volume of granite that could be produced by melting of the deep crust. Previous estimates based on melting experiments at low P (≤0.5 GPa) show substantial scatter when extrapolated to deep crustal P and T (700-1000 °C, 0.6-1.5 GPa). To improve the high-P constraints on H2O concentration at the granite liquidus, we performed experiments in a piston-cylinder apparatus at 1.0 GPa using a range of haplogranite compositions in the albite (Ab: NaAlSi3O8)—orthoclase (Or: KAlSi3O8)—quartz (Qz: SiO2)—H2O system. We used equal weight fractions of the feldspar components and varied the Qz between 20 and 30 wt%. In each experiment, synthetic granitic composition glass + H2O was homogenized well above the liquidus T, and T was lowered by increments until quartz and alkali feldspar crystalized from the liquid. To establish reversed equilibrium, we crystallized the homogenized melt at the lower T and then raised T until we found that the crystalline phases were completely resorbed into the liquid. The reversed liquidus minimum temperatures at 3.0, 4.1, 5.8, 8.0, and 12.0 wt% H2O are 935-985, 875-900, 775-800, 725-775, and 650-675 °C, respectively. Quenched charges were analyzed by petrographic microscope, scanning electron microscope (SEM), X-ray diffraction (XRD), and electron microprobe analysis (EMPA). The equation for the reversed haplogranite liquidus minimum curve for Ab36.25Or36.25Qz27.5 (wt% basis) at 1.0 GPa is T = - 0.0995 w_{{{H}_{ 2} {O}}}^{ 3} + 5.0242w_{{{H}_{ 2} {O}}}^{ 2} - 88.183 w_{{{H}_{ 2} {O}}} + 1171.0 for 0 ≤ w_{{{H}_{ 2} {O}}} ≤ 17 wt% and T is in °C. We present a revised P - T diagram of liquidus minimum H2O isopleths which integrates data from previous determinations of vapor-saturated melting and the lower pressure vapor-undersaturated melting studies conducted by other workers on

  11. Overview of experimental progress on understanding photon strength functions with an emphasis of the Oslo method (United States)

    Krticka, Milan


    The so-called Photon Strength Functions (PSFs) for different multipolarities are, together with the Nuclear Level Density (NLD) the key entities describing the statistical γ-decay of nucleus. It is well known that PSFs at energies above the threshold for particle emission are well described by the Lorentzian shape of the Giant Electric Dipole Resonance (GEDR). On the other hand, shapes of RSFs at the low-energy tail of GEDR are known rather poorly. Information on the PSFs at the GEDR tail can be obtained from several different experimental techniques. They will be summarized and the most important ones briefly introduced in this contribution. Special emphasis will be put on the so-called Oslo method which allows simultaneous extraction of the NLD and the PSFs from particle- γ coincidence measurements. This method has been used for determining the NLD and the PSFs in many nuclei in A ~ 45- 240 range during past years. Examples of the most interesting results obtained with this method will be shown. The results will be compared to information on the PSFs available from other experimental techniques. The strengths and the weaknesses of the method will be thoroughly discussed.

  12. Understanding electricity generation in osmotic microbial fuel cells through integrated experimental investigation and mathematical modeling. (United States)

    Qin, Mohan; Ping, Qingyun; Lu, Yaobin; Abu-Reesh, Ibrahim M; He, Zhen


    Osmotic microbial fuel cells (OsMFCs) are a new type of MFCs with integrating forward osmosis (FO). However, it is not well understood why electricity generation is improved in OsMFCs compared to regular MFCs. Herein, an approach integrating experimental investigation and mathematical model was adopted to address the question. Both an OsMFC and an MFC achieved similar organic removal efficiency, but the OsMFC generated higher current than the MFC with or without water flux, resulting from the lower resistance of FO membrane. Combining NaCl and glucose as a catholyte demonstrated that the catholyte conductivity affected the electricity generation in the OsMFC. A mathematical model of OsMFCs was developed and validated with the experimental data. The model predicated the variation of internal resistance with increasing water flux, and confirmed the importance of membrane resistance. Increasing water flux with higher catholyte conductivity could decrease the membrane resistance. Copyright © 2015 Elsevier Ltd. All rights reserved.

  13. Integrated Experimental and Computational Approach to Understand the Effects of Heavy Ion Radiation on Skin Homeostasis.

    Energy Technology Data Exchange (ETDEWEB)

    von Neubeck, Claere; Shankaran, Harish; Geniza, Matthew; Kauer, Paula M.; Robinson, Robert J.; Chrisler, William B.; Sowa, Marianne B.


    The effects of low dose high linear energy transfer (LET) radiation on human health are of concern for both space and clinical exposures. As epidemiological data for such radiation exposures are scarce for making relevant predictions, we need to understand the mechanism of response especially in normal tissues. Our objective here is to understand the effects of heavy ion radiation on tissue homeostasis in a realistic model system. Towards this end, we exposed an in vitro three dimensional skin equivalent to low fluences of Neon (Ne) ions (300 MeV/u), and determined the differentiation profile as a function of time following exposure using immunohistochemistry. We found that Ne ion exposures resulted in transient increases in the tissue regions expressing the differentiation markers keratin 10, and filaggrin, and more subtle time-dependent effects on the number of basal cells in the epidermis. We analyzed the data using a mathematical model of the skin equivalent, to quantify the effect of radiation on cell proliferation and differentiation. The agent-based mathematical model for the epidermal layer treats the epidermis as a collection of heterogeneous cell types with different proliferation/differentiation properties. We obtained model parameters from the literature where available, and calibrated the unknown parameters to match the observed properties in unirradiated skin. We then used the model to rigorously examine alternate hypotheses regarding the effects of high LET radiation on the tissue. Our analysis indicates that Ne ion exposures induce rapid, but transient, changes in cell division, differentiation and proliferation. We have validated the modeling results by histology and quantitative reverse transcription polymerase chain reaction (qRT-PCR). The integrated approach presented here can be used as a general framework to understand the responses of multicellular systems, and can be adapted to other epithelial tissues.


    Directory of Open Access Journals (Sweden)

    Héctor José Peinado-Guevara


    Full Text Available Hydraulic conductivity is a basic element in the advancement of knowledge of a geological environment in both the flow and transport processes of pollutants for conservation projects, managementand environmental management and also for the development of public policies for protection of ecosystems, among others. The aim of this paper is to obtain the hydraulic conductivity (K and the finescontent (C of saturated granular half using two empirical laws. One correlates the electrical conductivity of saturated granular media σo and water saturated σw which depends on the formation factor(F, cation exchange capacity (CEC and the fines content in the saturated soil. Using data obtained from materials of 18 samples from 6 wells the relationships between F-C and CEC-C were obtained,so the equation reduces to a σo function in terms of σw and C, with a correlation coefficient of R = 0.97. A second experimental law is the one that results from the experimental relationship between K and C,being 1.4054 K 0.1804.C with a correlation coefficient of R = 0.96. From both experimental expressions relationships between K and C, a and C,and C are created so from every pair knowing one of them you get to know the other one. Under the scheme outlined electrical conductivity sections for the saturated medium and fines content are obtained,finding that the groundwater in the study area consists of a thin top layer and beneath it there is a predominantly sandy environment.

  15. Experimental impact cratering provides ground truth data for understanding planetary-scale collision processes (United States)

    Poelchau, Michael H.; Deutsch, Alex; Kenkmann, Thomas


    Impact cratering is generally accepted as one of the primary processes that shape planetary surfaces in the solar system. While post-impact analysis of craters by remote sensing or field work gives many insights into this process, impact cratering experiments have several advantages for impact research: 1) excavation and ejection processes can be directly observed, 2) physical parameters of the experiment are defined and can be varied, and 3) cratered target material can be analyzed post-impact in an unaltered, uneroded state. The main goal of the MEMIN project is to comprehensively quantify impact processes by conducting a stringently controlled experimental impact cratering campaign on the meso-scale with a multidisciplinary analytical approach. As a unique feature we use two-stage light gas guns capable of producing impact craters in the decimeter size-range in solid rocks that, in turn, allow detailed spatial analysis of petrophysical, structural, and geochemical changes in target rocks and ejecta. In total, we have carried out 24 experiments at the facilities of the Fraunhofer EMI, Freiburg - Germany. Steel, aluminum, and iron meteorite projectiles ranging in diameter from 2.5 to 12 mm were accelerated to velocities ranging from 2.5 to 7.8 km/s. Targets were solid rocks, namely sandstone, quartzite and tuff that were either dry or saturated with water. In the experimental setup, high speed framing cameras monitored the impact process, ultrasound sensors were attached to the target to record the passage of the shock wave, and special particle catchers were positioned opposite of the target surface to capture the ejected target and projectile material. In addition to the cratering experiments, planar shock recovery experiments were performed on the target material, and numerical models of the cratering process were developed. The experiments resulted in craters with diameters up to 40 cm, which is unique in laboratory cratering research. Target porosity

  16. Experimental droughts: Are precipitation variability and methodological trends hindering our understanding of ecological sensitivities to drought? (United States)

    Hoover, D. L.; Wilcox, K.; Young, K. E.


    Droughts are projected to increase in frequency and intensity with climate change, which may have dramatic and prolonged effects on ecosystem structure and function. There are currently hundreds of published, ongoing, and new drought experiments worldwide aimed to assess ecosystem sensitivities to drought and identify the mechanisms governing ecological resistance and resilience. However, to date, the results from these experiments have varied widely, and thus patterns of drought sensitivities have been difficult to discern. This lack of consensus at the field scale, limits the abilities of experiments to help improve land surface models, which often fail to realistically simulate ecological responses to extreme events. This is unfortunate because models offer an alternative, yet complementary approach to increase the spatial and temporal assessment of ecological sensitivities to drought that are not possible in the field due to logistical and financial constraints. Here we examined 89 published drought experiments, along with their associated historical precipitation records to (1) identify where and how drought experiments have been imposed, (2) determine the extremity of drought treatments in the context of historical climate, and (3) assess the influence of precipitation variability on drought experiments. We found an overall bias in drought experiments towards short-term, extreme experiments in water-limited ecosystems. When placed in the context of local historical precipitation, most experimental droughts were extreme, with 61% below the 5th, and 43% below the 1st percentile. Furthermore, we found that interannual precipitation variability had a large and potentially underappreciated effect on drought experiments due to the co-varying nature of control and drought treatments. Thus detecting ecological effects in experimental droughts is strongly influenced by the interaction between drought treatment magnitude, precipitation variability, and key

  17. In-depth experimental analysis of pharmaceutical twin-screw wet granulation in view of detailed process understanding. (United States)

    Verstraeten, Maxim; Van Hauwermeiren, Daan; Lee, Kai; Turnbull, Neil; Wilsdon, David; Am Ende, Mary; Doshi, Pankaj; Vervaet, Chris; Brouckaert, Davinia; Mortier, Séverine T F C; Nopens, Ingmar; Beer, Thomas De


    Twin-screw wet granulation is gaining increasing interest within the pharmaceutical industry for the continuous manufacturing of solid oral dosage forms. However, limited prior fundamental physical understanding has been generated relating to the granule formation mechanisms and kinetics along the internal compartmental length of a twin-screw granulator barrel, and about how process settings, barrel screw configuration and formulation properties such as particle size, density and surface properties influence these mechanisms. One of the main reasons for this limited understanding is that experimental data is generally only collected at the exit of the twin-screw granulator barrel although the granule formation occurs spatially along the internal length of the barrel. The purpose of this study is to analyze the twin-screw wet granulation process using both hydrophilic and hydrophobic formulations, manufactured under different process settings such as liquid-to-solid ratio, mass throughput and screw speed, in such a way that the mechanisms occurring in the individual granulator barrel compartments (i.e., the wetting and different conveying and kneading compartments) and their impact upon granule formation are understood. To achieve this, a unique experimental setup was developed allowing granule characteristic data-collection such as size, shape, liquid and porosity distribution at the different compartments along the length of the granulator barrel. Moreover, granule characteristic information per granule size class was determined. The experimental results indicated that liquid-to-solid ratio is the most important factor dictating the formation of the granules and their corresponding properties, by regulating the degree of aggregation and breakage in the different compartments along the internal length of the twin-screw granulator barrel. Collecting appropriate and detailed experimental data about granule formation along the internal length of the granulator barrel

  18. Multifunctional light escaping architecture inspired by compound eye surface structures: From understanding to experimental demonstration. (United States)

    Song, Young Min; Park, Gyeong Cheol; Jang, Sung Jun; Ha, Jong Hoon; Yu, Jae Su; Lee, Yong Tak


    We present bioinspired artificial compound eye surface structures that consist of antireflective subwavelength structures (SWSs) on hexagonally patterned microstructures (MSs), for the purpose of efficient light escaping inside light-emitting materials/devices. Theoretical understanding and geometrical optimization of SWSs on MSs are described together with rigorous coupled-wave analysis. As a proof of this concept, AlGaInP red light-emitting diodes (LEDs) with SWS/MSs were fabricated, and a light output power enhancement of 72.47% was achieved as compared to that of conventional LEDs. The artificial compound eye structures are not limited to LEDs, and the fabrication process is compatible with most semiconductor device manufacturing processes; hence, this concept opens up new possibilities for improving the optical performance of various optoelectronic device applications.

  19. Experimental rig to improve the geophysical and geomechanical understanding of CO2 reservoirs (United States)

    Falcon-Suarez, Ismael; North, Laurence; Sothcott, Jeremy; Best, Angus


    with supercritical CO2 in the laboratory are performed on experimental rigs specially designed for conducting flow through porous media at high pressure conditions. Far from trivial, the rig must be carefully designed to meet the requirements of each simulating scenario: the accurate control of pore fluid, confining pressure, temperature and flow, and integrated monitoring tools are essential. Thus, we present a helpful protocol regarding the design and assembly of high pressure experimental rigs to supercritical CO2 injection tests.

  20. The Johnson Space Center Experimental Impact Lab: Contributions Toward Understanding the Evolution of the Solar System (United States)

    See, T. H.; Montes, R.


    Impact is the most common and only weathering phenomenon affecting all the planetary bodies (e.g., planets, satellites, asteroids, comets, etc.) in the solar system. NASA Johnson Space Center s Experimental Impact Laboratory (EIL) includes three accelerators that are used in support of research into the effects of impact on the formation and evolution of the solar system. They permit researchers to study a wide variety of phenomena associated with high-velocity impacts into a wide range of geologic targets and materials relevant to astrobiological studies. By studying these processes, researchers can investigate the histories and evolution of planetary bodies and the solar system as a whole. While the majority of research conducted in the EIL addresses questions involving planetary impacts, work involving spacecraft components has been performed on occasion. An example of this is the aerogel collector material flown on the Stardust spacecraft that traveled to Comet Wild-2. This capture medium was tested and flight qualified using the 5 mm Light-Gas Gun located in the EIL.

  1. Towards Understanding the Catalytic Mechanism of Human Paraoxonase 1: Experimental and In Silico Mutagenesis Studies. (United States)

    Tripathy, Rajan K; Aggarwal, Geetika; Bajaj, Priyanka; Kathuria, Deepika; Bharatam, Prasad V; Pande, Abhay H


    Human paraoxonase 1 (h-PON1) is a ~45-kDa serum enzyme that can hydrolyze a variety of substrates, including organophosphate (OP) compounds. It is a potential candidate for the development of antidote against OP poisoning in humans. However, insufficient OP-hydrolyzing activity of native enzyme affirms the urgent need to develop improved variant(s) having enhanced OP-hydrolyzing activity. The crystal structure of h-PON1 remains unsolved, and the molecular details of how the enzyme catalyses hydrolysis of different types of substrates are also not clear. Understanding the molecular details of the catalytic mechanism of h-PON1 is essential to engineer better variant(s) of enzyme. In this study, we have used a random mutagenesis approach to increase the OP-hydrolyzing activity of recombinant h-PON1. The mutants not only showed a 10-340-fold increased OP-hydrolyzing activity against different OP substrates but also exhibited differential lactonase and arylesterase activities. In order to investigate the mechanistic details of the effect of observed mutations on the hydrolytic activities of enzyme, molecular docking studies were performed with selected mutants. The results suggested that the observed mutations permit differential binding of substrate/inhibitor into the enzyme's active site. This may explain differential hydrolytic activities of the enzyme towards different substrates.

  2. Degraded core reflood. Present understanding based on experimental and analytical database and its impact on LWRs

    International Nuclear Information System (INIS)

    Hering, Wolfgang; Homann, Christoph


    The severe fuel damage (SFD) research at Forschungszentrum Karlsruhe started with the single rod experiments already before the TMI-2 accident revealed that the knowledge on accident initiation and progression was scarce. The general focus on primary circuit research was the understanding of processes, their interactions, and possibilities for countermeasures. But even today, the most prominent countermeasure, the flooding of a degraded core, is not yet completely understood, namely the influence of adverse effects such as enhanced core degradation and hydrogen spikes under the most probable scenarios. So far, the design basis accident procedures of core reflood can be extended to peak core temperatures of app. 2200 K, if sufficient reflood mss flow rate can be applied. Assuming an average core heat-up rate of 0.5 K/s, this gives only app. 12 min additional time with respect to DBA cases, but moreover a strategy for a successful core reflood before a large in-core pool is formed, which might be uncoolable. (author)

  3. Understanding Experimental LCMV Infection of Mice: The Role of Mathematical Models

    Directory of Open Access Journals (Sweden)

    Gennady Bocharov


    Full Text Available Virus infections represent complex biological systems governed by multiple-level regulatory processes of virus replication and host immune responses. Understanding of the infection means an ability to predict the systems behaviour under various conditions. Such predictions can only rely upon quantitative mathematical models. The model formulations should be tightly linked to a fundamental step called “coordinatization” (Hermann Weyl, that is, the definition of observables, parameters, and structures that enable the link with a biological phenotype. In this review, we analyse the mathematical modelling approaches to LCMV infection in mice that resulted in quantification of some fundamental parameters of the CTL-mediated virus control including the rates of T cell turnover, infected target cell elimination, and precursor frequencies. We show how the modelling approaches can be implemented to address diverse aspects of immune system functioning under normal conditions and in response to LCMV and, importantly, make quantitative predictions of the outcomes of immune system perturbations. This may highlight the notion that data-driven applications of meaningful mathematical models in infection biology remain a challenge.

  4. Spatial distribution of top soil water content in an experimental catchment of Southeast Brazil Distribuição espacial da umidade superficial do solo em uma bacia hidrográfica experimental do Sudeste do Brasil

    Directory of Open Access Journals (Sweden)

    Carlos Rogério de Mello


    Full Text Available Soil water content is essential to understand the hydrological cycle. It controls the surface runoff generation, water infiltration, soil evaporation and plant transpiration. This work aims to analyze the spatial distribution of top soil water content and to characterize the spatial mean and standard deviation of top soil water content over time in an experimental catchment located in the Mantiqueira Range region, state of Minas Gerais, Brazil. Measurements of top soil water content were carried out every 15 days, between May/2007 and May/2008. Using time-domain reflectometry (TDR equipment, 69 points were sampled in the top 0.2 m of the soil profile. Geostatistical procedures were applied in all steps of the study. First, the spatial continuity was evaluated, and the experimental semi-variogram was modeled. For the development of top soil water content maps over time a co-kriging procedure was used having the slope as a secondary variable. Rainfall regime controlled the top soil water content during the wet season. Land use was also another fundamental local factor. The spatial standard deviation had low values under dry conditions, and high values under wet conditions. Thus, more variability occurs under wet conditions.A umidade do solo é essencial para o entendimento do ciclo hidrológico, uma vez que controla a geração do escoamento superficial, infiltração de água no solo, evaporação do solo e transpiração das plantas. Este trabalho objetivou analisar os padrões espaciais da umidade superficial do solo e caracterizar a média e o desvio padrão espaciais da mesma ao longo do tempo em uma bacia hidrográfica experimental localizada na Serra da Mantiqueira, MG. As medidas da umidade superficial do solo foram conduzidas a cada 15 dias, entre Maio/2007 e Maio/2008, usando um equipamento TDR portátil, em 69 pontos amostrados na camada de 0-20 cm. Procedimentos geoestatísticos foram aplicados em todas as etapas do trabalho

  5. Modeling error in experimental assays using the bootstrap principle: understanding discrepancies between assays using different dispensing technologies (United States)

    Hanson, Sonya M.; Ekins, Sean; Chodera, John D.


    All experimental assay data contains error, but the magnitude, type, and primary origin of this error is often not obvious. Here, we describe a simple set of assay modeling techniques based on the bootstrap principle that allow sources of error and bias to be simulated and propagated into assay results. We demonstrate how deceptively simple operations—such as the creation of a dilution series with a robotic liquid handler—can significantly amplify imprecision and even contribute substantially to bias. To illustrate these techniques, we review an example of how the choice of dispensing technology can impact assay measurements, and show how large contributions to discrepancies between assays can be easily understood and potentially corrected for. These simple modeling techniques—illustrated with an accompanying IPython notebook—can allow modelers to understand the expected error and bias in experimental datasets, and even help experimentalists design assays to more effectively reach accuracy and imprecision goals.

  6. Understanding and Mitigating Reservoir Compaction: an Experimental Study on Sand Aggregates (United States)

    Schimmel, M.; Hangx, S.; Spiers, C. J.


    Fossil fuels continue to provide a source for energy, fuels for transport and chemicals for everyday items. However, adverse effects of decades of hydrocarbons production are increasingly impacting society and the environment. Production-driven reduction in reservoir pore pressure leads to a poro-elastic response of the reservoir, and in many occasions to time-dependent compaction (creep) of the reservoir. In turn, reservoir compaction may lead to surface subsidence and could potentially result in induced (micro)seismicity. To predict and mitigate the impact of fluid extraction, we need to understand production-driven reservoir compaction in highly porous siliciclastic rocks and explore potential mitigation strategies, for example, by using compaction-inhibiting injection fluids. As a first step, we investigate the effect of chemical environment on the compaction behaviour of sand aggregates, comparable to poorly consolidated, highly porous sandstones. The sand samples consist of loose aggregates of Beaujean quartz sand, sieved into a grainsize fraction of 180-212 µm. Uniaxial compaction experiments are performed at an axial stress of 35 MPa and temperature of 80°C, mimicking conditions of reservoirs buried at three kilometres depth. The chemical environment during creep is either vacuum-dry or CO2-dry, or fluid-saturated, with fluids consisting of distilled water, acid solution (CO2-saturated water), alkaline solution (pH 9), aluminium solution (pH 3) and solution with surfactants (i.e., AMP). Preliminary results show that compaction of quartz sand aggregates is promoted in a wet environment compared to a dry environment. It is inferred that deformation is controlled by subcritical crack growth when dry and stress corrosion cracking when wet, both resulting in grain failure and subsequent grain rearrangement. Fluids inhibiting these processes, have the potential to inhibit aggregate compaction.


    Directory of Open Access Journals (Sweden)

    Catherine Georgopoulou Theodosiou


    Full Text Available This paper focuses on the Content and Language Integrated Learning (CLIL method for (foreign language teaching. The CLIL approach is rapidly gaining momentum across Europe and all over the world. It is the result of recent European Union efforts to develop and apply innovative educational practices of interdisciplinary character in order to bridge the gap between foreign language education and optimum learning outcomes. In order to investigate the compatibility of CLIL with the contemporary Greek educational reality, a small-scale experimental research study was set up, including the development of original e-learning material, a pilot class instruction based on this material and the evaluation of the results. The class instruction was based on Project-Based Learning whereas Collaborative Learning was supported by the Edmodo e-learning platform. Information on the progress of the pilot class instruction and the learning outcomes achieved was disseminated through a wiki set up for this task.

  8. Understanding DRM acquisition of plates and spheres: a first comparative experimental approach (United States)

    Bilardello, Dario


    Since King presented the `plates and spheres' model in an attempt to investigate the origin of the inclination error in sediments, no one to date has conducted specific experiments designed to separate the individual contribution of platy and spherical particles to depositional remanent magnetizations (DRMs). It is commonly accepted that it is the flattening of plates, rather than the rolling of spheres that is the main source of inclination error in sediments. Recently, however, Bilardello et al. have shown that spheres alone may lead to significant amounts of shallowing. A comparison of experiments run in parallel using synthetic platy and spherical particles is presented. Experiments of the duration of 24 hr were run in 100 μT field intensity (μ0H) and varying field inclinations (IF) from vertical to horizontal. A systematic dependence of the magnetization on field inclination is apparent. Results indicate that magnetic moment measurements are more repeatable for spherical particles than for plates, yielding smaller uncertainties. Inclination measurements, however, are more repeatable for platy particles, with a more linear relationship of inclination error to applied field inclination. Moreover, plates yield smaller inclination error than spheres. A clear field inclination dependency of the inclination error also exists, with the error decreasing through field inclinations of 30°, 60° and 90°. A continuous acquisition experiment involving plates was also run up to 10 d of deposition in μ0H = 100 μT and IF = 60°. The acquisition curves for moment, inclination and thickness of depositing sediment are compared to the mean curves measured for spheres by Bilardello et al. under the same field conditions. No unequivocal evidence of compaction of the platy particles is observed, while the inclination error is acquired virtually instantaneously for all particles. These preliminary results contradict the widespread understanding that inclination shallowing is

  9. Assessment of leaf carotenoids content with a new carotenoid index: Development and validation on experimental and model data (United States)

    Zhou, Xianfeng; Huang, Wenjiang; Kong, Weiping; Ye, Huichun; Dong, Yingying; Casa, Raffaele


    Leaf carotenoids content (LCar) is an important indicator of plant physiological status. Accurate estimation of LCar provides valuable insight into early detection of stress in vegetation. With spectroscopy techniques, a semi-empirical approach based on spectral indices was extensively used for carotenoids content estimation. However, established spectral indices for carotenoids that generally rely on limited measured data, might lack predictive accuracy for carotenoids estimation in various species and at different growth stages. In this study, we propose a new carotenoid index (CARI) for LCar assessment based on a large synthetic dataset simulated from the leaf radiative transfer model PROSPECT-5, and evaluate its capability with both simulated data from PROSPECT-5 and 4SAIL and extensive experimental datasets: the ANGERS dataset and experimental data acquired in field experiments in China in 2004. Results show that CARI was the index most linearly correlated with carotenoids content at the leaf level using a synthetic dataset (R2 = 0.943, RMSE = 1.196 μg/cm2), compared with published spectral indices. Cross-validation results with CARI using ANGERS data achieved quite an accurate estimation (R2 = 0.545, RMSE = 3.413 μg/cm2), though the RBRI performed as the best index (R2 = 0.727, RMSE = 2.640 μg/cm2). CARI also showed good accuracy (R2 = 0.639, RMSE = 1.520 μg/cm2) for LCar assessment with leaf level field survey data, though PRI performed better (R2 = 0.710, RMSE = 1.369 μg/cm2). Whereas RBRI, PRI and other assessed spectral indices showed a good performance for a given dataset, overall their estimation accuracy was not consistent across all datasets used in this study. Conversely CARI was more robust showing good results in all datasets. Further assessment of LCar with simulated and measured canopy reflectance data indicated that CARI might not be very sensitive to LCar changes at low leaf area index (LAI) value, and in these conditions soil moisture

  10. Understanding of Technical Terms and Contents of Informed Consent Forms for Sedative Gastrointestinal Endoscopy Procedures

    Directory of Open Access Journals (Sweden)

    Ihnsook Jeong, RN, PhD


    Conclusion: The understanding of the terms and knowledge about the procedures were disappointing. Therefore, sufficient explanations should be provided to the patients. While the informed consent was taken by doctors, the level of understanding should be monitored by nurses. In particular, subjects who did not have any previous experience with endoscopy procedures showed relatively lower level of understanding. We recommend that medical terms should be replaced with more common and nontechnical words in consent forms.

  11. The Effects of an Interdisciplinary Undergraduate Human Biology Program on Socioscientific Reasoning, Content Learning, and Understanding of Inquiry (United States)

    Eastwood, Jennifer L.


    Preparing students to take informed positions on complex problems through critical evaluation is a primary goal of university education. Socioscientific issues (SSI) have been established as effective contexts for students to develop this competency, as well as reasoning skills and content knowledge. This mixed-methods study investigates the…

  12. Understanding small biomolecule-biomaterial interactions: a review of fundamental theoretical and experimental approaches for biomolecule interactions with inorganic surfaces. (United States)

    Costa, Dominique; Garrain, Pierre-Alain; Baaden, Marc


    Interactions between biomolecules and inorganic surfaces play an important role in natural environments and in industry, including a wide variety of conditions: marine environment, ship hulls (fouling), water treatment, heat exchange, membrane separation, soils, mineral particles at the earth's surface, hospitals (hygiene), art and buildings (degradation and biocorrosion), paper industry (fouling) and more. To better control the first steps leading to adsorption of a biomolecule on an inorganic surface, it is mandatory to understand the adsorption mechanisms of biomolecules of several sizes at the atomic scale, that is, the nature of the chemical interaction between the biomolecule and the surface and the resulting biomolecule conformations once adsorbed at the surface. This remains a challenging and unsolved problem. Here, we review the state of art in experimental and theoretical approaches. We focus on metallic biomaterial surfaces such as TiO(2) and stainless steel, mentioning some remarkable results on hydroxyapatite. Experimental techniques include atomic force microscopy, surface plasmon resonance, quartz crystal microbalance, X-ray photoelectron spectroscopy, fluorescence microscopy, polarization modulation infrared reflection absorption spectroscopy, sum frequency generation and time of flight secondary ion mass spectroscopy. Theoretical models range from detailed quantum mechanical representations to classical forcefield-based approaches. Copyright © 2012 Wiley Periodicals, Inc.

  13. Understanding the Usage of Content in a Mental Health Intervention for Depression: An Analysis of Log Data

    NARCIS (Netherlands)

    van Gemert-Pijnen, Julia E.W.C.; Kelders, Saskia Marion; Bohlmeijer, Ernst Thomas


    Background: Web-based interventions for the early treatment of depressive symptoms can be considered effective in reducing mental complaints. However, there is a limited understanding of which elements in an intervention contribute to effectiveness. For efficiency and effectiveness of interventions,

  14. Ecotoxicoparasitology: Understanding mercury concentrations in gut contents, intestinal helminths and host tissues of Alaskan gray wolves (Canis lupus) (United States)

    McGrew, Ashley K.; O'Hara, Todd M.; Stricker, Craig A.; Castellini, Margaret; Beckmen, Kimberlee B.; Salman, Mo D.; Ballweber, Lora R.


    Some gastrointestinal helminths acquire nutrients from the lumen contents in which they live; thus, they may be exposed to non-essential elements, such as mercury (Hg), during feeding. The objectives of this study were: 1) determine the total mercury concentrations ([THg]) in Gray wolves (Canis lupus) and their parasites, and 2) use stable isotopes to evaluate the trophic relationships within the host. [THg] and stable isotopes (C and N) were determined for helminths, host tissues, and lumen contents from 88 wolves. Sixty-three wolves contained grossly visible helminths (71.5%). The prevalence of taeniids and ascarids was 63.6% (56/88) and 20.5% (18/88), respectively. Nine of these 63 wolves contained both taeniids and ascarids (14.3%). All ascarids were determined to beToxascaris leonina. Taenia species present included T. krabbei and T. hydatigena. Within the GI tract, [THg] in the lumen contents of the proximal small intestine were significantly lower than in the distal small intestine. There was a significant positive association between hepatic and taeniid [THg]. Bioaccumulation factors (BAF) ranged from < 1 to 22.9 in taeniids, and 1.1 to 12.3 in T. leonina. Taeniid and ascarid BAF were significantly higher than 1, suggesting that both groups are capable of THg accumulation in their wolf host. δ13C in taeniids was significantly lower than in host liver and skeletal muscle. [THg] in helminths and host tissues, in conjunction with stable isotope (C and N) values, provides insight into food-web dynamics of the host GI tract, and aids in elucidating ecotoxicoparasitologic relationships. Variation of [THg] throughout the GI tract, and between parasitic groups, underscores the need to further evaluate the effect(s) of feeding niche, and the nutritional needs of parasites, as they relate to toxicant exposure and distribution within the host.

  15. Ecotoxicoparasitology: Understanding mercury concentrations in gut contents, intestinal helminths and host tissues of Alaskan gray wolves (Canis lupus)

    Energy Technology Data Exchange (ETDEWEB)

    McGrew, Ashley K. [Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523-1619 (United States); O' Hara, Todd M. [Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523-1619 (United States); Wildlife Toxicology Laboratory, Department of Veterinary Medicine, University of Alaska Fairbanks, Fairbanks, AK 99775 (United States); Stricker, Craig A. [U. S. Geological Survey, Fort Collins Science Center, Denver, CO 80225 (United States); Margaret Castellini, J. [Wildlife Toxicology Laboratory, Department of Veterinary Medicine, University of Alaska Fairbanks, Fairbanks, AK 99775 (United States); Beckmen, Kimberlee B. [Alaska Department of Fish & Game, Fairbanks, AK (United States); Salman, Mo D. [Animal Population Health Institute, Department of Clinical Sciences, Colorado State University, Fort Collins, CO 80523-1644 (United States); Ballweber, Lora R. [Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523-1619 (United States)


    Some gastrointestinal helminths acquire nutrients from the lumen contents in which they live; thus, they may be exposed to non-essential elements, such as mercury (Hg), during feeding. The objectives of this study were: 1) determine the total mercury concentrations ([THg]) in Gray wolves (Canis lupus) and their parasites, and 2) use stable isotopes to evaluate the trophic relationships within the host. [THg] and stable isotopes (C and N) were determined for helminths, host tissues, and lumen contents from 88 wolves. Sixty-three wolves contained grossly visible helminths (71.5%). The prevalence of taeniids and ascarids was 63.6% (56/88) and 20.5% (18/88), respectively. Nine of these 63 wolves contained both taeniids and ascarids (14.3%). All ascarids were determined to be Toxascaris leonina. Taenia species present included T. krabbei and T. hydatigena. Within the GI tract, [THg] in the lumen contents of the proximal small intestine were significantly lower than in the distal small intestine. There was a significant positive association between hepatic and taeniid [THg]. Bioaccumulation factors (BAF) ranged from < 1 to 22.9 in taeniids, and 1.1 to 12.3 in T. leonina. Taeniid and ascarid BAF were significantly higher than 1, suggesting that both groups are capable of THg accumulation in their wolf host. δ{sup 13}C in taeniids was significantly lower than in host liver and skeletal muscle. [THg] in helminths and host tissues, in conjunction with stable isotope (C and N) values, provides insight into food-web dynamics of the host GI tract, and aids in elucidating ecotoxicoparasitologic relationships. Variation of [THg] throughout the GI tract, and between parasitic groups, underscores the need to further evaluate the effect(s) of feeding niche, and the nutritional needs of parasites, as they relate to toxicant exposure and distribution within the host. - Highlights: • [THg] and stable isotopes together provide insight on host-parasite-Hg interactions. • A

  16. Intermediate-Scale Experimental Study to Improve Fundamental Understanding of Attenuation Capacity for Leaking CO2 in Heterogeneous Shallow Aquifers (United States)

    Plampin, Michael R.; Porter, Mark L.; Pawar, Rajesh J.; Illangasekare, Tissa H.


    To assess the risks of Geologic Carbon Sequestration (GCS), it is crucial to understand the fundamental physicochemical processes that may occur if and when stored CO2 leaks upward from a deep storage reservoir into the shallow subsurface. Intermediate-scale experiments allow for improved understanding of the multiphase evolution processes that control CO2 migration behavior in the subsurface, because the boundary conditions, initial conditions, and porous media parameters can be better controlled and monitored in the laboratory than in field settings. For this study, a large experimental test bed was designed to mimic a cross section of a shallow aquifer with layered geologic heterogeneity. As water with aqueous CO2 was injected into the system to mimic a CO2-charged water leakage scenario, the spatiotemporal evolution of the multiphase CO2 plume was monitored. Similar experiments were performed with two different sand combinations to assess the relative effects of different types of geologic facies transitions on the CO2 evolution processes. Significant CO2 attenuation was observed in both scenarios, but by fundamentally different mechanisms. When the porous media layers had very different permeabilities, attenuation was caused by local accumulation (structural trapping) and slow redissolution of gas phase CO2. When the permeability difference between the layers was relatively small, on the other hand, gas phase continually evolved over widespread areas near the leading edge of the aqueous plume, which also attenuated CO2 migration. This improved process understanding will aid in the development of models that could be used for effective risk assessment and monitoring programs for GCS projects.

  17. Experimental and theoretical investigation of the effect of SiO2 content in gate dielectrics on work function shift induced by nanoscale capping layers

    KAUST Repository

    Caraveo-Frescas, J. A.


    The impact of SiO2 content in ultrathin gate dielectrics on the magnitude of the effective work function (EWF) shift induced by nanoscale capping layers has been investigated experimentally and theoretically. The magnitude of the effective work function shift for four different capping layers (AlN, Al2O3, La2O3, and Gd2O3) is measured as a function of SiO2 content in the gate dielectric. A nearly linear increase of this shift with SiO2 content is observed for all capping layers. The origin of this dependence is explained using density functional theory simulations.

  18. Survey to explore understanding of the principles of aseptic technique: Qualitative content analysis with descriptive analysis of confidence and training. (United States)

    Gould, Dinah J; Chudleigh, Jane; Purssell, Edward; Hawker, Clare; Gaze, Sarah; James, Deborah; Lynch, Mary; Pope, Nicola; Drey, Nicholas


    In many countries, aseptic procedures are undertaken by nurses in the general ward setting, but variation in practice has been reported, and evidence indicates that the principles underpinning aseptic technique are not well understood. A survey was conducted, employing a brief, purpose-designed, self-reported questionnaire. The response rate was 72%. Of those responding, 65% of nurses described aseptic technique in terms of the procedure used to undertake it, and 46% understood the principles of asepsis. The related concepts of cleanliness and sterilization were frequently confused with one another. Additionally, 72% reported that they not had received training for at least 5 years; 92% were confident of their ability to apply aseptic technique; and 90% reported that they had not been reassessed since their initial training. Qualitative analysis confirmed a lack of clarity about the meaning of aseptic technique. Nurses' understanding of aseptic technique and the concepts of sterility and cleanliness is inadequate, a finding in line with results of previous studies. This knowledge gap potentially places patients at risk. Nurses' understanding of the principles of asepsis could be improved. Further studies should establish the generalizability of the study findings. Possible improvements include renewed emphasis during initial nurse education, greater opportunity for updating knowledge and skills post-qualification, and audit of practice. Copyright © 2018 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

  19. Pairing experimentation and computational modelling to understand the role of tissue inducer cells in the development of lymphoid organs

    Directory of Open Access Journals (Sweden)

    Kieran eAlden


    Full Text Available The use of genetic tools, imaging technologies and ex vivo culture systems has provided significant insights into the role of tissue inducer cells and associated signalling pathways in the formation and function of lymphoid organs. Despite advances in experimental technologies, the molecular and cellular process orchestrating the formation of a complex 3-dimensional tissue is difficult to dissect using current approaches. Therefore, a robust set of simulation tools have been developed to model the processes involved in lymphoid tissue development. Specifically the role of different tissue inducer cell populations in the dynamic formation of Peyer's Patches has been examined. Utilising approaches from critical systems engineering an unbiased model of lymphoid tissue inducer cell function has been developed, that permits the development of emerging behaviours that are statistically not different from that observed in vivo. These results provide the confidence to utilise statistical methods to explore how the simulator predicts cellular behaviour and outcomes under different physiological conditions. Such methods, known as sensitivity analysis techniques, can provide insight into when a component part of the system (such as a particular cell type, adhesion molecule, or chemokine begins to have an influence on observed behaviour, and quantifies the effect a component part has on the end result: the formation of lymphoid tissue. Through use of such a principled approach in the design, calibration, and analysis of a computer simulation, a robust in silico tool can be developed which can both further the understanding of a biological system being explored, and act as a tool for the generation of hypotheses which can be tested utilising experimental approaches.

  20. Learning the 'grammar of science': The influence of a physical science content course on teachers' understanding of the nature of science (United States)

    Hanuscin, Deborah L.

    This research examined the development of practicing K--8 teachers' views of the nature of science (NOS) within a physical science content course. Reforms in science education have called for the teaching of science as inquiry. In order to achieve the vision of the reforms, teachers must understand science, both a body of knowledge and as a process, but also the very nature of science itself-or the values and assumptions inherent in the construction of scientific knowledge. NOS has been deemed a critical component of scientific literacy, with implications for making informed decisions about scientific claims. Research has indicated that despite the emphasis of reforms, teachers generally do not possess accurate views of NOS. Recent work in science education has led to the recommendation that efforts undertaken within teacher education programs to improve teachers' understanding of NOS can be enhanced through relevant coursework in other academic areas, including the sciences. The purpose of this dissertation was to provide an empirical basis for this recommendation, by examining the development of teachers' views of NOS within a physical science content course. To this end, the researcher employed qualitative methodology including participant observation, interview, document analysis, and questionnaire to assess teacher participants' views of the nature of science and the impact of their experience in the content course on these views. As a result of this research, implications for both the course design and science teacher education have been described. In addition, various aspects of the community of practice that characterizes the classroom that inhibit the development of understandings about the nature of science are identified. It is argued that instruction in NOS should be approached from the perspective that builds bridges between the communities of practice of learners and of scientists.

  1. Development of Prediction Model and Experimental Validation in Predicting the Curcumin Content of Turmeric (Curcuma longa L.). (United States)

    Akbar, Abdul; Kuanar, Ananya; Joshi, Raj K; Sandeep, I S; Mohanty, Sujata; Naik, Pradeep K; Mishra, Antaryami; Nayak, Sanghamitra


    The drug yielding potential of turmeric ( Curcuma longa L.) is largely due to the presence of phyto-constituent 'curcumin.' Curcumin has been found to possess a myriad of therapeutic activities ranging from anti-inflammatory to neuroprotective. Lack of requisite high curcumin containing genotypes and variation in the curcumin content of turmeric at different agro climatic regions are the major stumbling blocks in commercial production of turmeric. Curcumin content of turmeric is greatly influenced by environmental factors. Hence, a prediction model based on artificial neural network (ANN) was developed to map genome environment interaction basing on curcumin content, soli and climatic factors from different agroclimatic regions for prediction of maximum curcumin content at various sites to facilitate the selection of suitable region for commercial cultivation of turmeric. The ANN model was developed and tested using a data set of 119 generated by collecting samples from 8 different agroclimatic regions of Odisha. The curcumin content from these samples was measured that varied from 7.2% to 0.4%. The ANN model was trained with 11 parameters of soil and climatic factors as input and curcumin content as output. The results showed that feed-forward ANN model with 8 nodes (MLFN-8) was the most suitable one with R 2 value of 0.91. Sensitivity analysis revealed that minimum relative humidity, altitude, soil nitrogen content and soil pH had greater effect on curcumin content. This ANN model has shown proven efficiency for predicting and optimizing the curcumin content at a specific site.

  2. Numerical and experimental studies on effects of moisture content on combustion characteristics of simulated municipal solid wastes in a fixed bed

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Rui, E-mail: [School of Energy Science and Engineering, Harbin Institute of Technology, 92, West Dazhi Street, Harbin 150001 (China); Ismail, Tamer M., E-mail: [Department of Mechanical Engineering, Suez Canal University, Ismailia (Egypt); Ren, Xiaohan [School of Energy Science and Engineering, Harbin Institute of Technology, 92, West Dazhi Street, Harbin 150001 (China); Abd El-Salam, M. [Department of Basic Science, Cairo University, Giza (Egypt)


    Highlights: • The effects of moisture content on the burning process of MSW are investigated. • A two-dimensional mathematical model was built to simulate the combustion process. • Temperature distributions, process rates, gas species were measured and simulated. • The The conversion ratio of C/CO and N/NO in MSW are inverse to moisture content. - Abstract: In order to reveal the features of the combustion process in the porous bed of a waste incinerator, a two-dimensional unsteady state model and experimental study were employed to investigate the combustion process in a fixed bed of municipal solid waste (MSW) on the combustion process in a fixed bed reactor. Conservation equations of the waste bed were implemented to describe the incineration process. The gas phase turbulence was modeled using the k–ε turbulent model and the particle phase was modeled using the kinetic theory of granular flow. The rate of moisture evaporation, devolatilization rate, and char burnout was calculated according to the waste property characters. The simulation results were then compared with experimental data for different moisture content of MSW, which shows that the incineration process of waste in the fixed bed is reasonably simulated. The simulation results of solid temperature, gas species and process rate in the bed are accordant with experimental data. Due to the high moisture content of fuel, moisture evaporation consumes a vast amount of heat, and the evaporation takes up most of the combustion time (about 2/3 of the whole combustion process). The whole bed combustion process reduces greatly as MSW moisture content increases. The experimental and simulation results provide direction for design and optimization of the fixed bed of MSW.

  3. Numerical and experimental studies on effects of moisture content on combustion characteristics of simulated municipal solid wastes in a fixed bed

    International Nuclear Information System (INIS)

    Sun, Rui; Ismail, Tamer M.; Ren, Xiaohan; Abd El-Salam, M.


    Highlights: • The effects of moisture content on the burning process of MSW are investigated. • A two-dimensional mathematical model was built to simulate the combustion process. • Temperature distributions, process rates, gas species were measured and simulated. • The The conversion ratio of C/CO and N/NO in MSW are inverse to moisture content. - Abstract: In order to reveal the features of the combustion process in the porous bed of a waste incinerator, a two-dimensional unsteady state model and experimental study were employed to investigate the combustion process in a fixed bed of municipal solid waste (MSW) on the combustion process in a fixed bed reactor. Conservation equations of the waste bed were implemented to describe the incineration process. The gas phase turbulence was modeled using the k–ε turbulent model and the particle phase was modeled using the kinetic theory of granular flow. The rate of moisture evaporation, devolatilization rate, and char burnout was calculated according to the waste property characters. The simulation results were then compared with experimental data for different moisture content of MSW, which shows that the incineration process of waste in the fixed bed is reasonably simulated. The simulation results of solid temperature, gas species and process rate in the bed are accordant with experimental data. Due to the high moisture content of fuel, moisture evaporation consumes a vast amount of heat, and the evaporation takes up most of the combustion time (about 2/3 of the whole combustion process). The whole bed combustion process reduces greatly as MSW moisture content increases. The experimental and simulation results provide direction for design and optimization of the fixed bed of MSW

  4. Effect of astragalus and dopamine on changes of blood and renal tissue contents of NO, ET in experimental rat models of acute renal failure

    International Nuclear Information System (INIS)

    Wu Yajun; Zheng Bingjie; Shi Lan; Fan Yaping


    Objective: To explore the effect of intravenous or intra-renal-capsular administration of astragalus and dopamine on the serum NO and renal tissue NO, ET contents in rat models of acute renal failure. Methods: Experimental rat models of acute renal failure induced by intraperitoneal injection of E. Coli endotoxin (lipo-polysaccharide) were prepared (n=60). Treatment with astragalus and dopamine was administered via either intravenous on intra-renal-capsular route (n=20 in each group). Serum NO and renal tissue NO (with nitric acid reductase method), ET (with RIA) contents were determined at 4, 8, 12, 16h after injection of endotoxin. Twenty shock models were left untreated and additional twenty rats receiving saline injection only served as controls. Results: In the intravenously treated group, the increase of serum NO and renal tissue NO, ET contents were significantly less than those in the untreated group (P<0.05). In the group treated via the intracapsular route , the increase of renal tissue NO and ET contents were much less than those in the intravenous group at 12 and 16h (P<0.05). Conclusion: Combined treatment with astragalus and dopamine could abate the abnormally high renal tissue contents of NO and ET after endotoxin shock in experimental rats and treatment with intra capsular administration seems to be more effective. (authors)

  5. Understanding the adsorption behavior of surface active molecules on ZnO nanostructures by experimental and first-principles calculations. (United States)

    Singh, Baljinder; Singh, Satvinder; Singh, Janpreet; Saini, G S S; Mehta, D S; Singh, Gurinder; Tripathi, S K; Kaura, Aman


    Zinc oxide (ZnO) nanostructures with different morphologies are prepared in the presence of surface active molecules such as sodium dodecyl sulphate (SDS), Tween 80 and Triton X-100 by a chemical method. The experimental and first principles methods are employed to understand the microscopic origin of the asymmetric growth mechanism of ZnO in the presence of various surface active molecules. Effect of increase in the amount of surface active molecules and temperature is studied on the growth morphology of ZnO. An innovative method is developed to synthesize ZnO nanowires (NWs) in the presence of SDS. Spherical nanoparticles (NPs) to spherical clusters are obtained in the presence of Triton X-100 and Tween 80. These results are then supported by first principles calculations. The adsorption of the -OH functional group on both polar and nonpolar surfaces of ZnO is modelled by using density functional theory (DFT). The calculated binding energy (BE) is almost equivalent on both the surfaces with no preference on any particular surface. The calculated value of BE shows that the -OH group is physio-adsorbed on both the surfaces. This results in the spherical morphology of nanoparticles prepared in the presence of Tween 80. Bader charge analysis shows that the charge transfer mainly takes place on top two layers of the ZnO(101[combining macron]0) surface. The absence of high values of electron localization function (ELF) reflects the lack of covalent bonding between the -OH group and the ZnO(101[combining macron]0) surface.

  6. The effects of ear-point stimulation on the contents of somatostatin and Amino acid neurotransmitters in brain of rat with experimental seizure. (United States)

    Shu, Jia; Liu, Rong-Yu; Huang, Xian-Fen


    The goal of this study was to elucidate the anti-convulsion mechanisms of ear-point stimulation in rat with experimental seizure. We prepared the epilepsy rats by intrahippocampal injection of penicillin. One hour later the lower 1/2 auricular lobules of seizure rats, containing ear-points Pizhixia and Shenmen etc., was electrically stimulated, which was imitated as ear-point electrical acupuncture in humans. Radioimmunoassay and biochemical techniques were used to determine the contents of somatostatin and amino acid neurotransmitters in hippocampus of rats. The outcomes revealed epileptiform behaviors of rat were appeared after penicillin-injected. The contents of somatostatin, aspartic acid, glutamine and GABA were increased. When these rats were subsequently given the ear-point electrical stimulation, the convulsion behaviors were definitely improved. At the same time the contents of the somatostatin, aspartic acid and glutamine in hippocampus of seizure rat were significantly decreased correspondingly. The contents of glycine, taurine and GABA had increased. Based on the results above, it was suggestive that ear-point electrical stimulation had anti-epilepsy effects, which might be involved in the decreases of the contents of the somatostatin, aspartic acid and glutamine, and increases of the contents of glycine, taurine and GABA in hippocampus of seizure rat.

  7. Effects of nutrient content claims, sports celebrity endorsements and premium offers on pre-adolescent children's food preferences: experimental research. (United States)

    Dixon, H; Scully, M; Niven, P; Kelly, B; Chapman, K; Donovan, R; Martin, J; Baur, L A; Crawford, D; Wakefield, M


    To assess pre-adolescent children's responses to common child-oriented front-of-pack food promotions. Between-subjects, web-based experiment with four front-of-pack promotion conditions on energy-dense and nutrient-poor (EDNP) foods: no promotion [control]; nutrient content claims; sports celebrity endorsements (male athletes) and premium offers. Participants were 1302 grade 5 and 6 children (mean age 11 years) from Melbourne, Australia. Participants chose their preferred product from a randomly assigned EDNP food pack and comparable healthier food pack then completed detailed product ratings. Child-oriented pack designs with colourful, cartooned graphics, fonts and promotions were used. Compared to the control condition, children were more likely to choose EDNP products featuring nutrient content claims (both genders) and sports celebrity endorsements (boys only). Perceptions of nutritional content were enhanced by nutrient content claims. Effects of promotions on some product ratings (but not choice) were negated when children referred to the nutrition information panel. Premium offers did not enhance children's product ratings or choice. Nutrient content claims and sports celebrity endorsements influence pre-adolescent children's preferences towards EDNP food products displaying them. Policy interventions to reduce the impact of unhealthy food marketing to children should limit the use of these promotions. © 2013 The Authors. Pediatric Obesity © 2013 International Association for the Study of Obesity.

  8. Evaluating the Gifted Students' Understanding Related to Plasma State Using Plasma Experimental System and Two-Tier Diagnostic Test (United States)

    Korkmaz, Saadet Deniz; Ayas, Bahadir; Aybek, Eren Can; Pat, Suat


    The purpose of this study was to investigate the effectiveness of the experimental system design related to plasma state on the gifted students' understanding on the subject of the plasma state. To test the research hypothesis, one group pretest-posttest research model was carried out with 18 eighth-grade (4 girls and 14 boys) gifted students in…

  9. Examining item content and structure in health status and health outcomes instruments: toward the development of a grammar for better understanding of the concepts being measured. (United States)

    Erickson, Pennifer; Willke, Richard J


    Health outcomes instruments assess diverse health concepts. Although item-level concepts are considered fundamental elements, the field lacks structures for evaluating and organizing them for decision making. This article proposes a grammar using item stems, response options, and recall periods to systematically identify item-level concepts. The grammar uses "core concept," "evaluative component," and "recall period" as intuitive terms for communicating with stakeholders. Better characterization of concepts is necessary for classifying instrument content and linking it to treatment benefit. Items in 2 generic and 21 disease-specific instruments were evaluated to develop and illustrate the use of the grammar. Concepts were assigned International Classification of Functioning, Disability and Health codes for exploring the value that the grammar and a classification system add to the understanding of content across instruments. The 23 instruments include many core concepts; emotional function is the only concept assessed in all instruments. Concepts in disease-specific instruments show obvious patterns; for example, arthritis instruments focus on physical function. The majority of instruments used the same response options across all items, with five-point scales being the most common. Most instruments used one recall period for all items. Shorter recall periods were used for conditions associated with "flares," such as chronic obstructive pulmonary disease and "skin disease." Every diagnosis, however, showed variation across instruments in the recall period used. This analysis indicates the proposed grammar's potential for discerning the conceptual content within and between health outcomes instruments and illustrates its value for improving communication between stakeholders and for making decisions related to treatment benefit. Copyright © 2013 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

  10. Experimental hyperglycemia induces an increase of monocyte and T-lymphocyte content in adipose tissue of healthy obese women.

    Directory of Open Access Journals (Sweden)

    Michaela Tencerová

    Full Text Available Hyperglycemia represents one of possible mediators for activation of immune system and may contribute to worsening of inflammatory state associated with obesity. The aim of our study was to investigate the effect of a short-term hyperglycemia (HG on the phenotype and relative content of immune cells in circulation and subcutaneous abdominal adipose tissue (SAAT in obese women without metabolic complications.Three hour HG clamp with infusion of octreotide and control investigations with infusion of octreotide or saline were performed in three groups of obese women (Group1: HG, Group 2: Octreotide, Group 3: Saline, n=10 per group. Before and at the end of the interventions, samples of SAAT and blood were obtained. The relative content of immune cells in blood and SAAT was determined by flow cytometry. Gene expression analysis of immunity-related markers in SAAT was performed by quantitative real-time PCR.In blood, no changes in analysed immune cell population were observed in response to HG. In SAAT, HG induced an increase in the content of CD206 negative monocytes/macrophages (p<0.05 and T lymphocytes (both T helper and T cytotoxic lymphocytes, p<0.01. Further, HG promoted an increase of mRNA levels of immune response markers (CCL2, TLR4, TNFα and lymphocyte markers (CD3g, CD4, CD8a, TBX21, GATA3, FoxP3 in SAAT (p<0.05 and 0.01. Under both control infusions, none of these changes were observed.Acute HG significantly increased the content of monocytes and lymphocytes in SAAT of healthy obese women. This result suggests that the short-term HG can modulate an immune status of AT in obese subjects.

  11. Experimental definition of technological modes of growth of biomass of a microalga Chlorella with the raised contents Lipids agricultural animals


    Dvoretsky, D.; Peshkova, E.; Temnov, M.


    The implementation of Chrorella vulgaris microalgae (strain IFR No. C-111) as a source of raw materials for third-generation biodiesel fuel production is justified. Experimental research has been conducted which allowed to develop techniques and modified broth for the cultivation of Chrorella vulgaris (strain IFR No. C-111) biomass rich in lipids.

  12. Naturalistic Experimental Designs as Tools for Understanding the Role of Genes and the Environment in Prevention Research. (United States)

    Leve, Leslie D; Neiderhiser, Jenae M; Harold, Gordon T; Natsuaki, Misaki N; Bohannan, Brendan J M; Cresko, William A


    Before genetic approaches were applied in experimental studies with human populations, they were used by animal and plant breeders to observe, and experimentally manipulate, the role of genes and environment on specific phenotypic or behavioral outcomes. For obvious ethical reasons, the same level of experimental control is not possible in human populations. Nonetheless, there are natural experimental designs in human populations that can serve as logical extensions of the rigorous quantitative genetic experimental designs used by animal and plant researchers. Applying concepts such as cross-fostering and common garden rearing approaches from the life science discipline, we describe human designs that can serve as naturalistic proxies for the controlled quantitative genetic experiments facilitated in life sciences research. We present the prevention relevance of three such human designs: (1) children adopted at birth by parents to whom they are not genetically related (common garden approach); (2) sibling designs where one sibling is reared from birth with unrelated adoptive parents and the other sibling is reared from birth by the biological mother of the sibling pair (cross-fostering approach); and (3) in vitro fertilization designs, including egg donation, sperm donation, embryo donation, and surrogacy (prenatal cross-fostering approach). Each of these designs allows for differentiation of the effects of the prenatal and/or postnatal rearing environment from effects of genes shared between parent and child in naturalistic ways that can inform prevention efforts. Example findings from each design type are provided and conclusions drawn about the relevance of naturalistic genetic designs to prevention science.

  13. False-belief understanding in 2.5-year-olds: evidence from violation-of-expectation change-of-location and unexpected-contents tasks (United States)

    He, Zijing; Bolz, Matthias; Baillargeon, Renée


    Until recently, it was generally assumed that the ability to attribute false beliefs did not emerge until about 4 years of age. However, recent reports using spontaneous- as opposed to elicited-response tasks have suggested that this ability may be present much earlier. To date, researchers have employed two kinds of spontaneous-response false-belief tasks: violation-of-expectation tasks have been used with infants in the second year of life, and anticipatory-looking tasks have been used with toddlers in the third year of life. In the present research, 2.5-year-old toddlers were tested in violation-of-expectation tasks involving a change-of-location situation (Experiment 1) and an unexpected-contents situation (Experiment 2). Results were positive in both situations, providing the first demonstrations of false-belief understanding in toddlers using violation-of-expectation tasks and, as such, pointing to a consistent and continuous picture of early false-belief understanding. PMID:22213902

  14. DCE-MRI using small-molecular and albumin-binding contrast agents in experimental carcinomas with different stromal content

    Energy Technology Data Exchange (ETDEWEB)

    Farace, Paolo; Merigo, Flavia; Fiorini, Silvia; Nicolato, Elena; Tambalo, Stefano; Daducci, Alessandro [Department of Morphological-Biomedical Sciences, Section of Anatomy and Histology, University of Verona, Verona (Italy); Degrassi, Anna [Nerviano Medical Sciences Institute, Milan (Italy); Sbarbati, Andrea [Department of Morphological-Biomedical Sciences, Section of Anatomy and Histology, University of Verona, Verona (Italy); Rubello, Domenico, E-mail: [Department of Radiology, Nuclear Medicine, Medical Physics, Services of Radiology and Nuclear Medicine, ' S. Maria della Misericordia' Hospital, Viale Tre Martiri 140, 45100 Rovigo (Italy); Marzola, Pasquina [Department of Morphological-Biomedical Sciences, Section of Anatomy and Histology, University of Verona, Verona (Italy)


    Objectives: To compare DCE-MRI experiments performed using a standard small-molecular (Gd-DTPA) and an albumin-binding (MS-325) contrast agent in two carcinoma models with different stromal content. Materials and methods: DU-145 or BXPC-3 cancer cells were subcutaneously injected into nude mice. DCE-MRI was performed by a bolus injection of Gd-DTPA or MS-325 about 2 weeks after inoculation. For quantitative analysis a volume of interest was manually drawn over each tumor. To address the heterogeneous enhancement, each tumor volume was then divided into the 20% most-enhancing and the remaining 80% least-enhancing fractions. Mean tumor enhancement was calculated over these selected tumor volumes and compared between tumor groups and contrast agents. Maps of differential enhancement, peak enhancement and time-to-peak were used for visual evaluation. CD31 and VEGF immunohistochemistry were performed in excised tumors. Results: In the 80% least-enhancing volume, at late time points of the dynamic scan, the mean enhancement elicited by MS-325 was higher in BXPC-3 than in DU-145 tumors. In the 20% most-enhancing volume, using either contrast agents, significant difference between the two tumors types were observed only early, while at later time points of the dynamic scan the difference were obscured by the faster washout observed in the BXPC-3 tumors. Enhancement maps confirmed that BXPC-3 tumors were characterized by marked washout rate using either contrast agent, particularly in the higher enhancing peripheral rim. With MS-325 this washout pattern appeared to be specific to the BXPC-3 carcinomas, since it was not observed in the DU-145 tumors. Finally, in both tumor types, MS-325 produced significantly higher enhancement than Gd-DTPA in the late phase of the dynamic scan. Ex vivo analysis confirmed the marked presence of aberrant infiltrative stroma in BXPC-3 tumors, in which tumor vessels were embedded. In all tumors the central portion was less viable and less

  15. Comparison of calculated and experimentally determined SID of CP and AA in complex diets differing in AA contents for grower finisher pigs. (United States)

    Büsing, K; Berk, A; Müller, S; Kieckhäven, S; Krüger, K; Zeyner, A


    In practice, the content of standardized ileal digestible AA in complex feeds for pigs is calculated on the basis of tabulated values for individual feedstuffs. It comes into question, however, whether this truly reflects an accurate content based upon the estimate made for the individual feedstuffs. The objective of this study was to compare standardized ileal digestibility (SID) of crude protein (CP) and selected AA in complex feeds for grower and finisher pigs either calculated or experimentally determined. Six diets with increasing AA levels were prepared for grower (BW from 30 to 70 kg) and finisher (BW from 70 to 120 kg) feed. Crystalline L-lys, DL-met and L-thr were added to both diets, L-trp and L-val only to the grower feed. SID of both CP and AA was calculated from feed tables and experimentally determined in six adult minipigs (MINILEWE) with ileorectal anastomosis. With increasing AA levels, experimentally determined SID of supplemented AA increased (p AA via tabulated values for individual feedstuffs, however, seems to be acceptable for practical use. Journal of Animal Physiology and Animal Nutrition © 2017 Blackwell Verlag GmbH.

  16. Developing Seventh Grade Students' Understanding of Complex Environmental Problems with Systems Tools and Representations: a Quasi-experimental Study (United States)

    Doganca Kucuk, Zerrin; Saysel, Ali Kerem


    A systems-based classroom intervention on environmental education was designed for seventh grade students; the results were evaluated to see its impact on the development of systems thinking skills and standard science achievement and whether the systems approach is a more effective way to teach environmental issues that are dynamic and complex. A quasi-experimental methodology was used to compare performances of the participants in various dimensions, including systems thinking skills, competence in dynamic environmental problem solving and success in science achievement tests. The same pre-, post- and delayed tests were used with both the comparison and experimental groups in the same public middle school in Istanbul. Classroom activities designed for the comparison group (N = 20) followed the directives of the Science and Technology Curriculum, while the experimental group (N = 22) covered the same subject matter through activities benefiting from systems tools and representations such as behaviour over time graphs, causal loop diagrams, stock-flow structures and hands-on dynamic modelling. After a one-month systems-based instruction, the experimental group demonstrated significantly better systems thinking and dynamic environmental problem solving skills. Achievement in dynamic problem solving was found to be relatively stable over time. However, standard science achievement did not improve at all. This paper focuses on the quantitative analysis of the results, the weaknesses of the curriculum and educational implications.

  17. Understanding Alzheimer's (United States)

    ... Navigation Bar Home Current Issue Past Issues Understanding Alzheimer's Past Issues / Fall 2007 Table of Contents For ... and brain scans. No treatment so far stops Alzheimer's. However, for some in the disease's early and ...

  18. Design and experimental verification of near-field Ka-band probe based on wideband OMJ with minimum higher-order spherical mode content

    DEFF Research Database (Denmark)

    Foged, L. J.; Giacomini, A.; Morbidini, R


    technology capable of maintaining the same high performance standards of traditional probes However, in typical Spherical Near Field (SNF) measurement scenarios, the applicable frequency range of the single probe can also be limited by the content of μ≠1 spherical modes in the probe pattern [6...... probe/AUT distance this assumption may lead to unacceptable errors in special cases. This paper describes the design and experimental verification of a Ka-band probe based on the inverted ridge technology. The probe is intended for high precision SNF measurements in special conditions that require less...... than -45dB higher order spherical mode content. This performance level has been accomplished through careful design of the probe and meticulous selection of the components used in the external balanced feeding scheme. The paper reports on the electrical and mechanical design considerations...

  19. A Science for Citizenship Model: Assessing the Effects of Benefits, Risks, and Trust for Predicting Students' Interest in and Understanding of Science-Related Content (United States)

    Jack, Brady Michael; Lee, Ling; Yang, Kuay-Keng; Lin, Huann-shyang


    This study showcases the Science for Citizenship Model (SCM) as a new instructional methodology for presenting, to secondary students, science-related technology content related to the use of science in society not taught in the science curriculum, and a new approach for assessing the intercorrelations among three independent variables (benefits, risks, and trust) to predict the dependent variable of triggered interest in learning science. Utilizing a 50-minute instructional presentation on nanotechnology for citizenship, data were collected from 301 Taiwanese high school students. Structural equation modeling (SEM) and paired-samples t-tests were used to analyze the fitness of data to SCM and the extent to which a 50-minute class presentation of nanotechnology for citizenship affected students' awareness of benefits, risks, trust, and triggered interest in learning science. Results of SCM on pre-tests and post-tests revealed acceptable model fit to data and demonstrated that the strongest predictor of students' triggered interest in nanotechnology was their trust in science. Paired-samples t-test results on students' understanding of nanotechnology and their self-evaluated awareness of the benefits and risks of nanotechology, trust in scientists, and interest in learning science revealed low significant differences between pre-test and post-test. These results provide evidence that a short 50-minute presentation on an emerging science not normally addressed within traditional science curriculum had a significant yet limited impact on students' learning of nanotechnology in the classroom. Finally, we suggest why the results of this study may be important to science education instruction and research for understanding how the integration into classroom science education of short presentations of cutting-edge science and emerging technologies in support of the science for citizenship enterprise might be accomplished through future investigations.

  20. Understanding patients’ decision-making strategies in hospital choice: Literature review and a call for experimental research

    Directory of Open Access Journals (Sweden)

    Sophia Fischer


    Full Text Available Insights from psychology and cognitive science have, as yet, barely entered hospital choice research. This conceptual article closes this gap by reviewing and conceptually framing the current literature on hospital choice and patient information behavior and by discussing which tools are needed to advance scientific methodology in the study of patient decision-making strategies in hospital choice. Specifically, we make a call for more experimental research in hospital choice in order to complement existing theories, methods, and tools. This article introduces computerized process-tracing tools in hospital choice research, and also outlines a hands-on example, to provide a basis for future research.

  1. Conceptual and Experimental Tools to Understand Spatial Effects and Transport Phenomena in Nonlinear Biochemical Networks Illustrated with Patchy Switching. (United States)

    Pompano, Rebecca R; Chiang, Andrew H; Kastrup, Christian J; Ismagilov, Rustem F


    Many biochemical systems are spatially heterogeneous and exhibit nonlinear behaviors, such as state switching in response to small changes in the local concentration of diffusible molecules. Systems as varied as blood clotting, intracellular calcium signaling, and tissue inflammation are all heavily influenced by the balance of rates of reaction and mass transport phenomena including flow and diffusion. Transport of signaling molecules is also affected by geometry and chemoselective confinement via matrix binding. In this review, we use a phenomenon referred to as patchy switching to illustrate the interplay of nonlinearities, transport phenomena, and spatial effects. Patchy switching describes a change in the state of a network when the local concentration of a diffusible molecule surpasses a critical threshold. Using patchy switching as an example, we describe conceptual tools from nonlinear dynamics and chemical engineering that make testable predictions and provide a unifying description of the myriad possible experimental observations. We describe experimental microfluidic and biochemical tools emerging to test conceptual predictions by controlling transport phenomena and spatial distribution of diffusible signals, and we highlight the unmet need for in vivo tools.

  2. Influence of viscosity and amine content on C==C conversion and color stability of experimental composites. (United States)

    Camargo, Fernanda Missio; Della Bona, Álvaro; Moraes, R R; Coutinho de Souza, C R; Schneider, Luis Felipe


    To investigate the influence of camphorquinone (CQ):amine ratio on the degree of CC conversion (DC) and color stability of experimental dental composites formulated with different co-monomer viscosities, indirectly determined by variations in the co-monomer ratios. Experimental composites were formulated in two different BisGMA:TEGDMA molar ratios (50:50 and 70:30). Viscosities were assessed with a viscometer. For each composite formulation, four different CQ:amine ratios were added: 1:1, 1:2, 1:3 or 1:4 mol%. Materials were loaded with 40 wt% of silanized glass particles. DC was determined by Fourier-transformed infrared spectroscopy with attenuated reflectance mode (ATR-FTIR). A spectrophotometer was used to measure the CIE L*a*b* color coordinates 24h after polymerization and after 2 months stored in water. Color changes (ΔE) were calculated. Data were statistically analyzed using analyses of variance (ANOVA), Tukey's and Student-t tests (α=0.05). The 50:50 BisGMA:TEGDMA co-monomer showed lower viscosity than 70:30. DC was affected by CQ:amine ratio, and not by the co-monomer viscosity, but the interaction between these two factors was significant. a* and b* coordinates were dependent on CQ:amine or BisGMA:TEGDMA ratios, while L* was not. b* values were directly related to the amount of amine in the formulation, regardless of co-monomer viscosity. ΔE was dependent on the amount of amine, but not on the viscosity of the material. DC was influenced by the CQ:amine ratio. The influence of viscosity on DC was dependent on the CQ:amine ratio and exhibited distinguished behavior. a* and b* coordinates were affected by CQ:amine and BisGMA:TEGDMA ratios. The color change (ΔE) was affected by CQ:amine ratio, but not by viscosity. Copyright © 2015 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

  3. Learning Design of Problem Based Learning Model Based on Recommendations of Sintax Study and Contents Issues on Physics Impulse Materials with Experimental Activities

    Directory of Open Access Journals (Sweden)

    Kristia Agustina


    Full Text Available This study aims to design learning Problem Based Learning Model based on syntax study recommendations and content issues on Physics Impulse materials through experiments. This research is a development research with Kemp model. The reference for making the learning design is the result of the syntax study and the content of existing PBL implementation problems from Agustina research. This instructional design is applied to the physics material about Impulse done through experimental activity. Limited trials were conducted on the SWCU Physics Education Study Program students group Salatiga, while the validity test was conducted by high school teachers and physics education lecturers. The results of the trial evaluation are limited and the validity test is used to improve the designs that have been made. The conclusion of this research is the design of learning by using PBL model on Impuls material by referring the result of syntax study and the problem content of existing PBL implementation can be produced by learning activity designed in laboratory experiment activity. The actual problem for Impuls material can be used car crash test video at factory. The results of validation tests and limited trials conducted by researchers assessed that the design of learning made by researchers can be used with small revisions. Suggestions from this research are in making learning design by using PBL model to get actual problem can by collecting news that come from newspaper, YouTube, internet, and television.

  4. Correlation between spermatogenesis disorders and rat testes CYP2E1 mRNA contents under experimental alcoholism or type I diabetes. (United States)

    Shayakhmetova, Ganna M; Bondarenko, Larysa B; Matvienko, Anatoliy V; Kovalenko, Valentina M


    The aim of the study was to investigate the correlation between spermatogenesis disorders and CYP2E1 mRNA contents in testes of rats with experimental alcoholism or type I diabetes. Two pathological states characterized by CYP2E1 induction were simulated on Wistar male rats: experimental alcoholism and type I diabetes. As controls for each state, equal number of animals (of the same age and weight) were used. Morphological evaluation of rat testes was carried out. The spermatogenic epithelium state was estimated by four points system. CYP2E1 mRNA expression was rated by method of reverse transcriptase polymerase chain reaction. Pearson correlation coefficients were used for describing relationships between variables. The presence of alcoholism and diabetes-mediated quantitative and qualitative changes in male rat spermatogenic epithelium in comparison with norm has been demonstrated. The increased levels of testes CYP2E1 have been fixed simultaneously. CYP2E1 mRNA content negatively strongly correlated with spermatogenic index value (r=-0.99; Palcoholism. The strong correlation between CYP2E1 mRNA content and number of spermatogonia (r=0.99; P<0.001) and "windows" occurrence (r=0.96; P<0.001) has been fixed in diabetic rats testes. Present investigation has demonstrated that the testicular failure following chronic ethanol consumption and diabetes type I in male rats accompanied CYP2E1 mRNA over-expression in testes. The correlation between the levels of CYP2E1 mRNA in testes and spermatogenesis disorders allow supposing the involvement of CYP2E1 into the non-specific pathogenetic mechanisms of male infertility under above-mentioned pathologies. Copyright © 2014 Medical University of Bialystok. Published by Elsevier Urban & Partner Sp. z o.o. All rights reserved.

  5. A Review on Experimental Measurements for Understanding Efficiency Droop in InGaN-Based Light-Emitting Diodes

    Directory of Open Access Journals (Sweden)

    Lai Wang


    Full Text Available Efficiency droop in GaN-based light emitting diodes (LEDs under high injection current density perplexes the development of high-power solid-state lighting. Although the relevant study has lasted for about 10 years, its mechanism is still not thoroughly clear, and consequently its solution is also unsatisfactory up to now. Some emerging applications, e.g., high-speed visible light communication, requiring LED working under extremely high current density, makes the influence of efficiency droop become more serious. This paper reviews the experimental measurements on LED to explain the origins of droop in recent years, especially some new results reported after 2013. Particularly, the carrier lifetime of LED is analyzed intensively and its effects on LED droop behaviors are uncovered. Finally, possible solutions to overcome LED droop are discussed.

  6. An experimental comparison of the understanding and use of speaker-addressee personal pronouns in autistic children. (United States)

    Jordan, R R


    Eleven autistic children were compared to normally developing children and mentally handicapped children, matched by receptive vocabulary age, on their understanding and use of the personal pronouns 'you' and 'me'. There were no significant differences between the groups in their comprehension of these terms, where the terms could be understood simply as referential labels. There was, however, a marked difference in the production of 'me' and 'you'. Only two autistic children showed the same pattern of responses that was shown by all but 4 of the 22 control children. The autistic children showed almost no 'pronoun reversal'. Instead, they used incorrect case pronouns or proper names for self or other reference. The results are interpreted in the light of significant difficulties in the acquisition of person deixis in autistic children.

  7. Research goes to School: understanding the content and the procedures of Science through a new dialogue among students, teachers and scientists (United States)

    L'Astorina, Alba; Tomasoni, Irene


    The Education system is increasingly interested in a more interactive dialogue with scientists in order to make science taught at school more aware of the models and the ways in which knowledge is produced, revised and discussed within the scientific community. Not always, in fact, the ministerial programs, the media, and the textbooks adopted by schools seem to be able to grasp the content and the procedures of the scientific knowledge as it is today being developed, sometimes spreading the idea of a monolithic and static science, with no reference to revisions, uncertainties, errors and disputes that, on the opposite, characterize the debate about science. On the other side, scientists, that in several surveys define students and teachers as one of the key groups that are most important to communicate with, often do not seem to be aware that scientific knowledge is continuously revised by the school and its protagonists. Science teaching, in all classes, has a highly educational role, as it offers the opportunity to value individual differences, to make students acquire specific tools and methods that enable them understand the world and critically interact with it. In this process of conscious learning, in which teachers play the role of tutors, the student participates actively bringing his tacit knowledge and beliefs. In this context, an educational proposal has recently been developed by the Italian National Research Council (CNR), aimed at starting a new dialogue between Education and Research. It's a way to encourage the technical and scientific culture among young people and a mutual exchange between the two main actors of the scientific production and promotion, considering weaknesses and strengths of the relationship between these two systems. In this proposal, students and teachers follow side by side a group of CNR scientists involved in an ongoing research project based on the use of innovative methodologies of aerospace Earth Observation (EO) for

  8. From one plot to many and from hillslopes to streams: Improving our understanding of catchment hydrology with a multi-scale experimental approach (United States)

    Blume, Theresa; Weiler, Markus; Angermann, Lisa; Beiter, Daniel; Hassler, Sibylle; Kaplan, Nils; Lieder, Ernestine; Sprenger, Matthias


    Sustainable water resources management needs to be based on sound process understanding. This is especially true in a changing world, where boundary conditions change and models calibrated to the status quo are no longer helpful. There is a general agreement in the hydrologic community that we are in need of a better process understanding and that one of the most promising ways to achieve this is by using nested experimental designs that cover a range of scales. In the here presented study we argue that while we might be able to investigate a certain process at a plot or hillslope in detail, the real power of advancing our understanding lies in site intercomparison and if possible knowledge transfer and generalization. The experimental design of the CAOS observatory is based on sensor clusters measuring ground-, soil and stream water, sap flow and climate variables in 45 hydrological functional units which were chosen from a matrix of site characteristics (geology, land use, hillslope aspect, and topographic positions). This design allows for site intercomparisons that are based on more than one member per class and thus does not only characterize between class differences but also attempts to identify within-class variability. These distributed plot scale investigations offer a large amount of information on plot scale processes and their variability in space and time (e.g. water storage dynamics and patterns, vertical flow processes and vadose zone transit times, transpiration dynamics and patterns). However, if we want to improve our understanding of runoff generation (and thus also of nutrient and contaminant transport and export to the stream) we need to also understand how these plots link up within hillslopes and how and when these hillslopes are connected to the stream. And certainly, this is again most helpful if we do not focus on single sites but attempt experimental designs that aim at intercomparison and generalization. At the same time, the

  9. Experimental Watershed Study Designs: A Tool for Advancing Process Understanding and Management of Mixed-Land-Use Watersheds (United States)

    Hubbart, J. A.; Kellner, R. E.; Zeiger, S. J.


    Advancements in watershed management are both a major challenge, and urgent need of this century. The experimental watershed study (EWS) approach provides critical baseline and long-term information that can improve decision-making, and reduce misallocation of mitigation investments. Historically, the EWS approach was used in wildland watersheds to quantitatively characterize basic landscape alterations (e.g. forest harvest, road building). However, in recent years, EWS is being repurposed in contemporary multiple-land-use watersheds comprising a mosaic of land use practices such as urbanizing centers, industry, agriculture, and rural development. The EWS method provides scalable and transferrable results that address the uncertainties of development, while providing a scientific basis for total maximum daily load (TMDL) targets in increasing numbers of Clean Water Act 303(d) listed waters. Collaborative adaptive management (CAM) programs, designed to consider the needs of many stakeholders, can also benefit from EWS-generated information, which can be used for best decision making, and serve as a guidance tool throughout the CAM program duration. Of similar importance, long-term EWS monitoring programs create a model system to show stakeholders how investing in rigorous scientific research initiatives improves decision-making, thereby increasing management efficiencies through more focused investments. The evolution from classic wildland EWS designs to contemporary EWS designs in multiple-land-use watersheds will be presented while illustrating how such an approach can encourage innovation, cooperation, and trust among watershed stakeholders working to reach the common goal of improving and sustaining hydrologic regimes and water quality.

  10. Iron Carbides in Fischer–Tropsch Synthesis: Theoretical and Experimental Understanding in Epsilon-Iron Carbide Phase Assignment

    International Nuclear Information System (INIS)

    Liu, Xing-Wu; Cao, Zhi; Zhao, Shu; Gao, Rui


    As active phases in low-temperature Fischer–Tropsch synthesis for liquid fuel production, epsilon iron carbides are critically important industrial materials. However, the precise atomic structure of epsilon iron carbides remains unclear, leading to a half-century of debate on the phase assignment of the ε-Fe 2 C and ε’-Fe 2.2 C. Here, we resolve this decades-long question by a combining theoretical and experimental investigation to assign the phases unambiguously. First, we have investigated the equilibrium structures and thermal stabilities of ε-Fe x C, (x = 1, 2, 2.2, 3, 4, 6, 8) by first-principles calculations. We have also acquired X-ray diffraction patterns and Mössbauer spectra for these epsilon iron carbides, and compared them with the simulated results. These analyses indicate that the unit cell of ε-Fe 2 C contains only one type of chemical environment for Fe atoms, while ε’-Fe 2.2 C has six sets of chemically distinct Fe atoms.

  11. The Ever-Evolving Concept of the Gene: The Use of RNA/Protein Experimental Techniques to Understand Genome Functions

    Directory of Open Access Journals (Sweden)

    Andrea Cipriano


    Full Text Available The completion of the human genome sequence together with advances in sequencing technologies have shifted the paradigm of the genome, as composed of discrete and hereditable coding entities, and have shown the abundance of functional noncoding DNA. This part of the genome, previously dismissed as “junk” DNA, increases proportionally with organismal complexity and contributes to gene regulation beyond the boundaries of known protein-coding genes. Different classes of functionally relevant nonprotein-coding RNAs are transcribed from noncoding DNA sequences. Among them are the long noncoding RNAs (lncRNAs, which are thought to participate in the basal regulation of protein-coding genes at both transcriptional and post-transcriptional levels. Although knowledge of this field is still limited, the ability of lncRNAs to localize in different cellular compartments, to fold into specific secondary structures and to interact with different molecules (RNA or proteins endows them with multiple regulatory mechanisms. It is becoming evident that lncRNAs may play a crucial role in most biological processes such as the control of development, differentiation and cell growth. This review places the evolution of the concept of the gene in its historical context, from Darwin's hypothetical mechanism of heredity to the post-genomic era. We discuss how the original idea of protein-coding genes as unique determinants of phenotypic traits has been reconsidered in light of the existence of noncoding RNAs. We summarize the technological developments which have been made in the genome-wide identification and study of lncRNAs and emphasize the methodologies that have aided our understanding of the complexity of lncRNA-protein interactions in recent years.

  12. Experimental contribution to the understanding of the dynamics of spreading of Newtonian fluids: effect of volume, viscosity and surfactant. (United States)

    Roques-Carmes, Thibault; Mathieu, Vincent; Gigante, Alexandra


    The dynamics of drop spreading of glycerol-water mixtures with and without surfactant on hydrophilic glass surfaces has been investigated. The influence of different factors, such as viscosity, drop volume and non-ionic alkyl (8-16) glucoside (Plantacare) surfactant concentration on the number and the nature of the spreading regimes is systematically investigated. More than 25 spreading experiments have been performed in order to obtain clear trends. The results confirm the existence of several spreading regimes for the duration of an experiment (200 s). For each regime, the radius can be expressed by a power law of the form R=Kt(n). Both n and K are necessary to identify the regime. The experimental data are compared with the analytical predictions of the combined theory of spreading. One of the main results of this study is that the nature of the regimes is strongly affected by the drop volume, the viscosity and the surfactant concentration. This behavior is not predicted by the theory. For drop volume less than or equal to 15 microL, a succession of two different regimes which depend on the viscosity and surfactant concentration are observed in the following order: a molecular-kinetic regime followed by a hydrodynamic regime (for high viscosity in the presence of surfactant) or a hydrodynamic regime and lastly a final asymptotic regime corresponding to a long relaxation time to equilibrium (for high viscosity in absence of surfactant and for low viscosity regardless of the presence of surfactant). The spreading follows quantitatively the predictions of the theory. Our results demonstrate that the theory is still valid for low viscosity liquids and in the presence of surfactant. The contact angle for which the crossover between molecular-kinetic regime and hydrodynamic regime occurs is thoroughly estimated since the theories do not allow the exact calculation of this value. Here for the first time, an empirical power law exponent (n=0.08+/-0.05) is proposed for

  13. An experimental seasonal hydrological forecasting system over the Yellow River basin - Part 1: Understanding the role of initial hydrological conditions (United States)

    Yuan, Xing; Ma, Feng; Wang, Linying; Zheng, Ziyan; Ma, Zhuguo; Ye, Aizhong; Peng, Shaoming


    The hydrological cycle over the Yellow River has been altered by the climate change and human interventions greatly during past decades, with a decadal drying trend mixed with a large variation of seasonal hydrological extremes. To provide support for the adaptation to a changing environment, an experimental seasonal hydrological forecasting system is established over the Yellow River basin. The system draws from a legacy of a global hydrological forecasting system that is able to make use of real-time seasonal climate predictions from North American Multimodel Ensemble (NMME) climate models through a statistical downscaling approach but with a higher resolution and a spatially disaggregated calibration procedure that is based on a newly compiled hydrological observation dataset with 5 decades of naturalized streamflow at 12 mainstream gauges and a newly released meteorological observation dataset including 324 meteorological stations over the Yellow River basin. While the evaluation of the NMME-based seasonal hydrological forecasting will be presented in a companion paper to explore the added values from climate forecast models, this paper investigates the role of initial hydrological conditions (ICs) by carrying out 6-month Ensemble Streamflow Prediction (ESP) and reverse ESP-type simulations for each calendar month during 1982-2010 with the hydrological models in the forecasting system, i.e., a large-scale land surface hydrological model and a global routing model that is regionalized over the Yellow River. In terms of streamflow predictability, the ICs outweigh the meteorological forcings up to 2-5 months during the cold and dry seasons, but the latter prevails over the former in the predictability after the first month during the warm and wet seasons. For the streamflow forecasts initialized at the end of the rainy season, the influence of ICs for lower reaches of the Yellow River can be 5 months longer than that for the upper reaches, while such a difference

  14. The Effects of Design Strength, Fly Ash Content and Curing Method on Compressive Strength of High Volume Fly Ash Concrete: A Design of Experimental

    Directory of Open Access Journals (Sweden)

    Solikin Mochamad


    Full Text Available High volume fly ash concrete becomes one of alternatives to produce green concrete as it uses waste material and significantly reduces the utilization of Portland cement in concrete production. Although using less cement, its compressive strength is comparable to ordinary Portland cement (hereafter OPC and the its durability increases significantly. This paper reports investigation on the effect of design strength, fly ash content and curing method on compressive strength of High Volume Fly Ash Concrete. The experiment and data analysis were prepared using minitab, a statistic software for design of experimental. The specimens were concrete cylinder with diameter of 15 cm and height of 30 cm, tested for its compressive strength at 56 days. The result of the research demonstrates that high volume fly ash concrete can produce comparable compressive strength which meets the strength of OPC design strength especially for high strength concrete. In addition, the best mix proportion to achieve the design strength is the combination of high strength concrete and 50% content of fly ash. Moreover, the use of spraying method for curing method of concrete on site is still recommended as it would not significantly reduce the compressive strength result.

  15. Adaptive radiation of Pseudomonas fluorescens SBW25 in experimental microcosms provides an understanding of the evolutionary ecology and molecular biology of A-L interface biofilm formation. (United States)

    Koza, Anna; Kusmierska, Anna; McLaughlin, Kimberley; Moshynets, Olena; Spiers, Andrew J


    Combined experimental evolutionary and molecular biology approaches have been used to investigate the adaptive radiation of Pseudomonas fluorescens SBW25 in static microcosms leading to the colonisation of the air-liquid interface by biofilm-forming mutants such as the Wrinkly Spreader (WS). In these microcosms, the ecosystem engineering of the early wild-type colonists establishes the niche space for subsequent WS evolution and colonisation. Random WS mutations occurring in the developing population that deregulate diguanylate cyclases and c-di-GMP homeostasis result in cellulose-based biofilms at the air-liquid interface. These structures allow Wrinkly Spreaders to intercept O2 diffusing into the liquid column and limit the growth of competitors lower down. As the biofilm matures, competition increasingly occurs between WS lineages, and niche divergence within the biofilm may support further diversification before system failure when the structure finally sinks. A combination of pleiotropic and epistasis effects, as well as secondary mutations, may explain variations in WS phenotype and fitness. Understanding how mutations subvert regulatory networks to express intrinsic genome potential and key innovations providing a selective advantage in novel environments is key to understanding the versatility of bacteria, and how selection and ecological opportunity can rapidly lead to substantive changes in phenotype and in community structure and function. © FEMS 2017. All rights reserved. For permissions, please e-mail:

  16. Attrition during a randomized controlled trial of reduced nicotine content cigarettes as a proxy for understanding acceptability of nicotine product standards. (United States)

    Mercincavage, Melissa; Wileyto, E Paul; Saddleson, Megan L; Lochbuehler, Kirsten; Donny, Eric C; Strasser, Andrew A


    To determine (1) if nicotine content affects study attrition-a potential behavioral measure of acceptability-in a trial that required compliance with three levels of reduced nicotine content (RNC) cigarettes, and (2) if attrition is associated with subjective and behavioral responses to RNC cigarettes. Secondary analysis of a 35-day, parallel-design, open-label, randomized controlled trial. After a 5-day baseline period, participants were randomized to smoke for three 10-day periods: their preferred brand (control group) or RNC cigarettes with three nicotine levels in a within-subject stepdown (one group: high-moderate-low) or non-stepdown (five groups: high-low-moderate, low-moderate-high, low-high-moderate, moderate-low-high, moderate-high-low) fashion. A single site in Philadelphia, PA, USA. A total of 246 non-treatment-seeking daily smokers [mean age = 39.52, cigarettes per day (CPD) = 20.95, 68.3% white] were recruited from October 2007 to June 2013. The primary outcome was attrition. Key predictors were nicotine content transition and study period. Exploratory predictors were taste and strength subjective ratings, total puff volume and carbon monoxide (CO) boost. Covariates included: age, gender, race, education and nicotine dependence. Overall attrition was 31.3% (n = 77): 24.1% of the control and 25.0% of the stepdown RNC cigarette groups dropped out versus 44.6% of non-stepdown groups (P = 0.006). Compared with controls, attrition odds were 4.5 and 4.7 times greater among smokers transitioning from preferred and the highest RNC cigarettes to the lowest RNC cigarettes, respectively (P = 0.001 and 0.003). Providing more favorable initial taste ratings of study cigarettes decreased attrition odds by 2% (P = 0.012). The majority of participants completed a 35-day trial of varying levels of reduced nicotine content cigarettes. Participant dropout was greater for cigarettes with lower nicotine content and less in smokers reporting more favorable

  17. Content identification: binary content fingerprinting versus binary content encoding (United States)

    Ferdowsi, Sohrab; Voloshynovskiy, Svyatoslav; Kostadinov, Dimche


    In this work, we address the problem of content identification. We consider content identification as a special case of multiclass classification. The conventional approach towards identification is based on content fingerprinting where a short binary content description known as a fingerprint is extracted from the content. We propose an alternative solution based on elements of machine learning theory and digital communications. Similar to binary content fingerprinting, binary content representation is generated based on a set of trained binary classifiers. We consider several training/encoding strategies and demonstrate that the proposed system can achieve the upper theoretical performance limits of content identification. The experimental results were carried out both on a synthetic dataset with different parameters and the FAMOS dataset of microstructures from consumer packages.

  18. [Determination of deuterium concentration in foods and influence of water with modified isotopic composition on oxidation parameters and heavy hydrogen isotopes content in experimental animals]. (United States)

    Basov, A A; Bykov, I M; Baryshev, M G; Dzhimak, S S; Bykov, M I


    The article presents the results of the study of the deuterium (D) content in food products as well as the influence of deuterium depleted water (DDW) on the concentration of heavy hydrogen isotopes in the blood and lyophilized tissues of rats. The most significant difference in the content of D was found between potato and pork fat, which indexes the standard delta notation (δ) D in promille, related to the international standard SMOW (Standard Mean Ocean of Water) amounted to -83,2 per thousand and -250,7 per thousand, respectively (phydrogen atoms in the body. The data obtained in the experimental modeling of the diet of male Wistar rats in the age of 5-6 mo (weight 235 ± 16 g) using DDW (δD = -743,2 per thousand) instead of drinking water (δD = -37,0 per thousand) with identical mineral composition showed that after 2 weeks significant (p tissue") is due to different rates ofisotopic exchange reactions in plasma and tissues (liver, kidney, heart), which can be explained by entering into the composition of a modified diet of organic substrates with more than DDW concentration D, which are involved in the construction of cellular structures and eventually lead to a redistribution of D and change direction of D/H gradient "plasma

  19. Understanding the processes involved in weathering and experimental alteration of glassy materials. The case of some volcanic glasses from eastern Sicily (Italy)

    International Nuclear Information System (INIS)

    Liotta, Angelo


    The objective of this thesis is to study the effects of weathering and experimental alteration in order to understand the geochemical processes involved and the variation of mineral phases in altered natural glasses. For the first time, five samples of natural volcanic glasses having different composition were collected in eastern Sicily (Italy) in order to be artificially altered and analyzed. The study of naturally altered samples has allowed to observe the effects of weathering after a period of time corresponding to the age of the sample. Moreover, the use of samples of natural glass of volcanic origin has allowed to obtain some powder or thin plates of fresh silicate glass that have been subjected to artificial alteration in the laboratory, in order to model the geochemical processes that have occurred. Alteration experiments were conducted in pure water at 90 C; samples have been altered from 1 to 1000 days of experiment. The characterization of the samples was obtained by Raman spectroscopy, which showed the effects of the devitrification and the presence of some secondary minerals such as carbonates and anatase on the obsidian thin plates, but also phillipsite and chabazite, two varieties of zeolite usually found in the cavities of oldest basalts. Solid modifications were observed by SEM. The analysis showed the formation of several secondary minerals having a composition compatible with smectites, determined by EDS spectroscopy. All these results allow to test the geochemical modeling in the long term. Further analysis will be needed to reach a full understanding of the weathering of glassy materials. (author)

  20. Teaching Teaching & Understanding Understanding

    DEFF Research Database (Denmark)


    "Teaching Teaching & Understanding Understanding" is a 19-minute award-winning short-film about teaching at university and higher-level educational institutions. It is based on the "Constructive Alignment" theory developed by Prof. John Biggs. The film delivers a foundation for understanding what...

  1. X-Ray Contrast Media Mechanisms in the Release of Mast Cell Contents: Understanding These Leads to a Treatment for Allergies

    Directory of Open Access Journals (Sweden)

    Elliott C. Lasser


    Full Text Available A long history of searching for the etiology of X-ray contrast material (CM reactions has led to the understanding that the CM do not produce anti-CM antigens. Since CM reactions are anaphylactoid in nature, however, a source for mast cell activation was sought. This resulted in the finding that concentrated CM could suppress mast cell activation by attachment to the Fc portion of IgE and IgG. This is presumed to be a steric hindrance effect. In a study of the effects of CM on BP and a study of the effects of CM in sensitized rats, it was concluded that less concentrated CM activated mast cells and that this mechanism was best explained by bridging of adjacent IgE molecules via attachment to their Fc segments. The mast cell release of heparin activating the contact system, as well as the release of histamine, is believed to be responsible for CM reactions and allergic diatheses.

  2. Experimental design and statistical analysis of data to assign a value to uranium content in rubidium uranium (IV) trisulphate - a possible standard reference material (SRM) for uranium (Preprint no. AC-10)

    International Nuclear Information System (INIS)

    Yadav, M.B.; Singh, Hari; Vaidyanathan, S.; Sood, D.D.


    An experimental design based on a Randomised Block Design (RBD) was prepared to assign a value to uranium content in Rubidium Uranium(IV) Trisulphate (RUS). Effects of factors such as method, inhomogenity and lot were studied. Lots were found to be homogeneous and lot-lot variation was significant. Method-method variation was found highly significant dividing the data into three significantly different groups. These values were pooled together to arrive at a single value, (34.144±.020)% for the uranium content in the RUS. (author)

  3. Particle and impurity transport in the Axial Symmetric Divertor Experiment Upgrade and the Joint European Torus, experimental observations and theoretical understanding

    DEFF Research Database (Denmark)

    Angioni, C.; Carraro, L.; Dannert, T.


    Experimental observations on core particle and impurity transport from the Axial Symmetric Divertor Experiment Upgrade [O. Gruber, H.-S. Bosch, S. Gunter , Nucl Fusion 39, 1321 (1999)] and the Joint European Torus [J. Pamela, E. R. Solano, and JET EFDA Contributors, Nucl. Fusion 43, 1540 (2003......)] tokamaks are reviewed and compared. Robust general experimental behaviors observed in both the devices and related parametric dependences are identified. The experimental observations are compared with the most recent theoretical results in the field of core particle transport. (C) 2007 American Institute...

  4. Effect of experimental silane-based primers with various contents of 2-hydroxyethyl methacrylate on the bond strength of orthodontic adhesives. (United States)

    Mustafa, Ammar A; Matinlinna, Jukka P; Razak, Aziz A; Hussin, Akbar S


    To evaluate in vitro the effect of different concentrations of 2-hydroxyethyl methacrylate (HEMA) in experimental silane-based primers on shear bond strength of orthodontic adhesives. Different volume percentages of HEMA were tested in four experimental silane-based primer solutions (additions of HEMA: 0, 5.0 vol%, 25.0 vol% and 50.0 vol%). An experimental silane blend (primer) of 1.0 vol% 3-isocyanatopropyltrimethoxysilane (ICMS) + 0.5% bis-1,2-(triethoxysilyl) ethane (BTSE) was prepared and used. The experimental primers together with the control group were applied onto acid-etched premolars for attachment of orthodontic brackets. After artificial aging by thermocycling the shear-bond strength was measured. The fractured surfaces of all specimens were examined under scanning electron microscopy (SEM) to evaluate the failure mode on the enamel surface. The experimental primers showed the highest shear-bond strength of 21.15 MPa (SD ± 2.70 MPa) and with 25 vol% showed a highly significant increase (P silane-based primers. In addition, the SEM images suggested that the predominant failure type was not necessarily the same as for the failure propagation. This preliminary study suggested that nonacidic silane-based primers with HEMA addition might be an alternative to for use as adhesion promoting primers. © 2014 Wiley Publishing Asia Pty Ltd.

  5. Independent component analysis for understanding multimedia content

    DEFF Research Database (Denmark)

    Kolenda, Thomas; Hansen, Lars Kai; Larsen, Jan


    classification rates increase if based on multimedia components relative to single media analysis. For this purpose a simple probabilistic supervised classifier which works from unsupervised ICA features is invoked. In addition, we demonstrate the suggested framework for automatic annotation of descriptive key...

  6. The Effects of Design Strength, Fly Ash Content and Curing Method on Compressive Strength of High Volume Fly Ash Concrete: A Design of Experimental


    Solikin Mochamad; Setiawan Budi


    High volume fly ash concrete becomes one of alternatives to produce green concrete as it uses waste material and significantly reduces the utilization of Portland cement in concrete production. Although using less cement, its compressive strength is comparable to ordinary Portland cement (hereafter OPC) and the its durability increases significantly. This paper reports investigation on the effect of design strength, fly ash content and curing method on compressive strength of High Volume Fly ...

  7. An experimental study: quantitatively evaluating the change of the content of collagen fibres in penis with two-dimensional ShearWave™ Elastography. (United States)

    Qiao, X-H; Zhang, J-J; Gao, F; Li, F; Bai, M; Du, L-F; Xing, J-F


    The purpose of this study was to explore the value of two-dimensional ShearWave ™ Elastography (2D-SWE) on quantitatively evaluating the change of the content of collagen fibres in penis. Twenty male Sprague Dawley rats were divided into the pre-sexual maturity group (Group 1) and the sexual decline group (Group 2) according to age. The ultrafast ultrasound device Aixplorer ® (SuperSonic Imagine, Aix-en-Provence, France) was used for 2D-SWE imaging of penis, and the measurement index was shear wave stiffness (SWS). The immunohistochemistry was used to analyse the content of collagen fibres in penis, and the measurement index was positive area percentage (PAP). The differences of SWS between the two groups and PAP between the two groups were analysed. SWS of Group 1 and Group 2 was 10.18 ± 1.09 and 8.02 ± 1.34 kPa, and SWS of Group 2 was significantly lower than Group 1 (p penis measured with 2D-SWE would change significantly as well. Two-dimensional SWE can be used to quantitatively evaluate the change of the content of collagen fibres in penis. © 2016 Blackwell Verlag GmbH.

  8. Landscape structure, groundwater dynamics, and soil water content influence soil respiration across riparian-hillslope transitions in the Tenderfoot Creek Experimental Forest, Montana (United States)

    Vincent J. Pacific; Brian L. McGlynn; Diego A. Riveros-Iregui; Daniel L. Welsch; Howard E. Epstein


    Variability in soil respiration at various spatial and temporal scales has been the focus of much research over the last decade aimed to improve our understanding and parameterization of physical and environmental controls on this flux. However, few studies have assessed the control of landscape position and groundwater table dynamics on the spatiotemporal variability...

  9. Naturalising Representational Content (United States)

    Shea, Nicholas


    This paper sets out a view about the explanatory role of representational content and advocates one approach to naturalising content – to giving a naturalistic account of what makes an entity a representation and in virtue of what it has the content it does. It argues for pluralism about the metaphysics of content and suggests that a good strategy is to ask the content question with respect to a variety of predictively successful information processing models in experimental psychology and cognitive neuroscience; and hence that data from psychology and cognitive neuroscience should play a greater role in theorising about the nature of content. Finally, the contours of the view are illustrated by drawing out and defending a surprising consequence: that individuation of vehicles of content is partly externalist. PMID:24563661

  10. An Experimental and Modeling Study of NOx-CO Formation in High Hydrogen Content (HHC) Fuels Combustion in Gas Turbine Applications

    Energy Technology Data Exchange (ETDEWEB)

    Farouk, Tanvir [Univ. of South Carolina, Columbia, SC (United States); Padak, Bihter [Univ. of South Carolina, Columbia, SC (United States); Dryer, Frederick [Univ. of South Carolina, Columbia, SC (United States)


    Species concentration measurements specifically those associated with NOx can act as important validation targets for developing kinetic models to predict NOx emissions under syngas as well as natural gas combustion accurately. In this collaborative research effort that included both experimental measurements, model development and simulations a comprehensive kinetic model and a multiphysics computational fluid dynamics platform has been developed and validated against the experimental data available in the literature as well as those acquired under this project. The experimental data provide the necessary NOx and speciation data for conditions relevant to gas turbine operations but are not readily available in the literature. The comprehensive chemical kinetic model consists of CO/H2/NOx oxidation with the full implementation of NOx evolution pathways, including thermal, prompt, N2O and NNH paths. The experiments conducted included NOx perturbed oxidation of natural gas at elevated pressure in laminar flow reactor and syngas/air combustion in a McKenna Burner – Flow Tube setup. A wide range of equivalence ratio, operating pressure as well as H2/CO ratio (for syngas only) was investigated. Temperature and NOx concentrations were measured in the flame and post-combustion zone. Experiments were also conducted for seeded syngas where trace hydrocarbon was introduced. The proposed model has been extensively tested. Predictions from the model are compared against multiple experimental datasets over a wide range of venues and operating conditions. The experimental venues include shock tube, plug flow reactor, and stirred reactor experiments that cover pressures from 1 to 100 bar and equivalence ratios from 0.5 to 1.5. In general, the overall model predictions are in good agreement with global combustion targets, such as ignition delay time, as well as with more

  11. Experimental nitrogen, phosphorus, and potassium deposition decreases summer soil temperatures, water contents, and soil CO2 concentrations in a northern bog

    Directory of Open Access Journals (Sweden)

    C. Blodau


    Full Text Available Ombrotrophic peatlands depend on airborne nitrogen (N, whose deposition has increased in the past and lead to disappearance of mosses and increased shrub biomass in fertilization experiments. The response of soil water content, temperature, and carbon gas concentrations to increased nutrient loading is poorly known and we thus determined these data at the long-term N fertilization site Mer Bleue bog, Ontario, during a two month period in summer. Soil temperatures decreased with NPK addition in shallow peat soil primarily during the daytime (t-test, p p RMANOVA, which also suggested an influence of volumetric water contents as co-variable on soil temperature and vice versa (p RMANOVA (p 2 concentrations in the near-surface peat (t-test, p < 0.05 were lower with increasing N load, suggesting more rapid soil gas exchange. The results thus suggest that changes in bog ecosystem structure with N deposition have significant ramifications for physical parameters that in turn control biogeochemical processes.

  12. Experimental Forests and climate change: views of long-term employees on ecological change and the role of Experimental Forests and Ranges in understanding and adapting to climate change (United States)

    Laurie Yung; Mason Bradbury; Daniel R. Williams


    In this project, we examined the views of 21 long-term employees on climate change in 14 Rocky Mountain Research Station Experimental Forests and Ranges (EFRs). EFRs were described by employees as uniquely positioned to advance knowledge of climate change impacts and adaptation strategies due to the research integrity they provide for long-term studies, the ability to...

  13. The Impact of Experimental Hypoxia and Subsequent Normoxia on the Content of Some Ions and Markers of Physiological Stress-adaptation in Gastropod Species Lymnaea stagnalis

    Directory of Open Access Journals (Sweden)

    Lubyaga J.А.


    Full Text Available The purpose of this study was to evaluate the influence of hypoxia and subsequent normoxiaon the maintenance of respiratory pigment hemocyanin, total protein, lactate and some ions (Na +, K +, Ca2+, NH4+, Mg2+ in the mantle liquid in palaearctic gastropod species Lymnaea stagnalis. It was shown that short-term experimental hypoxia leads to the activation of the physiological mechanisms of stress adaptation in widespread Palaearctic eurybiotic gastropod species and does not lead to the activation of the stress-resistance mechanisms on the biochemical and molecular levels.

  14. A model to investigate intention understanding in autism?. Comment on "Seeing mental states: An experimental strategy for measuring the observability of other minds" by Cristina Becchio et al. (United States)

    Forbes, Paul A. G.; Hamilton, Antonia F. de C.


    Becchio et al. [2] specify the conditions under which mental states are observable in the kinematics of other agents. Given that autistic people display differences in their understanding of other's mental states [1] and show an insensitivity to the kinematics of co-actors' movements [5,10], what are the implications of Becchio et al.'s strategy for the study of autism?

  15. ¿What about bullying?¿ An experimental field study to understand students¿ attitudes towards bullying and victimization in Italian middle schools

    NARCIS (Netherlands)

    Baldry, A.C.


    Background. Attitudes towards bullying at school are influential in understanding and preventing bullying behaviour but they should be measured with reference to the particular conditions under which bullying takes place. Aims. To establish how far positive and negative judgments of bullying and

  16. Understanding Prenatal Tests (United States)

    ... Navigation Bar Home Current Issue Past Issues Understanding Prenatal Tests Past Issues / Winter 2008 Table of Contents ... be done before pregnancy or at the first prenatal visit. If there is Rh incompatibility, treatments can ...

  17. Economics and International Understanding. (United States)

    Chandra, Ramesh


    A methodology linking the teaching of economics to the promotion of international understanding is discussed. The content of a course dealing with the new international economic order is examined. (Author/RM)

  18. Do behavioral scientists really understand HIV-related sexual risk behavior? A systematic review of longitudinal and experimental studies predicting sexual behavior. (United States)

    Huebner, David M; Perry, Nicholas S


    Behavioral interventions to reduce sexual risk behavior depend on strong health behavior theory. By identifying the psychosocial variables that lead causally to sexual risk, theories provide interventionists with a guide for how to change behavior. However, empirical research is critical to determining whether a particular theory adequately explains sexual risk behavior. A large body of cross-sectional evidence, which has been reviewed elsewhere, supports the notion that certain theory-based constructs (e.g., self-efficacy) are correlates of sexual behavior. However, given the limitations of inferring causality from correlational research, it is essential that we review the evidence from more methodologically rigorous studies (i.e., longitudinal and experimental designs). This systematic review identified 44 longitudinal studies in which investigators attempted to predict sexual risk from psychosocial variables over time. We also found 134 experimental studies (i.e., randomized controlled trials of HIV interventions), but of these only 9 (6.7 %) report the results of mediation analyses that might provide evidence for the validity of health behavior theories in predicting sexual behavior. Results show little convergent support across both types of studies for most traditional, theoretical predictors of sexual behavior. This suggests that the field must expand the body of empirical work that utilizes the most rigorous study designs to test our theoretical assumptions. The inconsistent results of existing research would indicate that current theoretical models of sexual risk behavior are inadequate, and may require expansion or adaptation.

  19. All-trans retinoic acid induces nerve regeneration and increases serum and nerve contents of neural growth factor in experimental diabetic neuropathy. (United States)

    Hernández-Pedro, Norma; Ordóñez, Graciela; Ortiz-Plata, Alma; Palencia-Hernández, Guadalupe; García-Ulloa, Ana Cristina; Flores-Estrada, Diana; Sotelo, Julio; Arrieta, Oscar


    Local diminution of the neural growth factor (NGF) contributes to the apparition of diabetic neuropathy. All-trans retinoic acid (RA) increases the expression of neural growth factor and its receptor participating in translation pathways. This study evaluates RA as a treatment of diabetic neuropathy: 120 mice were assigned randomly to 4 groups. Group A (n = 30) was taken as control; group B (n = 30) received 50 mg/kg intraperitoneal streptozotocin (STZ); group C (n = 30) received STZ, and after diabetic neuropathy developed, they were treated with subcutaneous RA 20 mg/kg daily during 60 days; and group D (n = 30) only received RA. Plasma glucose, thermosensitive tests, serum, and the nerve contents of NGF were measured in all animals. Evaluation by electron microscopy was performed in search of morphologic changes secondary to neuropathy and nerve regeneration. Diabetic mice had an increased threshold to pain. Treatment with RA in diabetic mice reverted changes in sensitivity as compared with diabetic mice that received placebo (P pain threshold among controls, RA, and diabetes mellitus (DM) + RA groups were found. Glucose levels were not affected by the treatment with RA. NGF diminished significantly in the sciatic nerve in diabetic mice as compared with controls and with the RA group. Animals with DM + RA had a significant increase of NGF in nerves as compared with the other groups. RA also regressed the ultrastructural changes induced by diabetes that showed increased neural regeneration. RA can revert functional and ultrastructural changes and induce neural regeneration after the establishment of diabetic neuropathy, possibly because of the increased of NGF concentrations in nerve terminals.

  20. Stevia rebaudiana Bertoni as a source of bioactive compounds: the effect of harvest time, experimental site and crop age on steviol glycoside content and antioxidant properties. (United States)

    Tavarini, Silvia; Angelini, Luciana G


    This study was aimed at identifying the effect of harvest time, experimental site and crop age on the no-calorie sweetener steviol glycosides (SG) and on the antioxidant properties of stevia leaf extracts. The experiment was conducted over two growing seasons at two sites in the northeastern plain of Italy. The results showed that all analysed factors played an important role in defining the SG profile and the antioxidant properties of stevia extracts. A high level of phenols (78.24 mg GAE g⁻¹ DW by Folin-Ciocalteu method) and high antioxidant activity (812.6 µmol Fe²⁺ g⁻¹ DW by FRAP assay) were observed. The inhibition of DPPH free radicals was evaluated and an IC₅₀ mean value of 250 µg mL⁻¹ was obtained. Significant relationships among the total antioxidant capacity and the analysed compounds were found. The results showed the possibility of obtaining, in the tested environments, very high SG yields thanks to the long-day conditions during the spring/summer season. The harvest time played a key role in determining the stevia quality, influencing the rebaudioside A/stevioside ratio. The strong antioxidant properties make very interesting the possibility of using stevia extracts to improve functional food properties. © 2012 Society of Chemical Industry.

  1. Experimental investigation of flow-induced fabrics in rocks at upper-mantle pressures. Application to understanding mantle dynamics and seismic anisotropy

    Energy Technology Data Exchange (ETDEWEB)

    Durham, William B. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)


    The goal of this collaborative research effort between W.B. Durham at the Massachusetts Institute of Technology (MIT) and D.L. Kohlstedt and S. Mei at the University of Minnesota (UMN) was to exploit a newly developed technology for high-pressure, high-temperature deformation experimentation, namely, the deformation DIA (D-DIA), to determine the deformation behavior of a number of important upper mantle rock types including olivine, garnet, enstatite, and periclase. Experiments were carried out under both hydrous and anhydrous conditions and at both lithospheric and asthenospheric stress and temperature conditions. The result was a group of flow laws for Earth’s upper mantle that quantitatively describe the viscosity of mantle rocks from shallow depths (the lithosphere) to great depths (the asthenosphere). These flow laws are fundamental for modeling the geodynamic behavior and heat transport from depth to Earth’s surface.-

  2. Experimental investigation of flow-induced fabrics in rocks at upper-mantle pressures: Application to understanding mantle dynamics and seismic anisotropy

    Energy Technology Data Exchange (ETDEWEB)

    Kohlstedt, David L. [Univ. of Minnesota, Minneapolis, MN (United States)


    The goal of this collaborative research effort between W.B. Durham at the Massachusetts Institute of Technology (MIT) and D.L. Kohlstedt and S. Mei at the University of Minnesota (UMN) was to exploit a newly developed technology for high-pressure, high-temperature deformation experimentation, namely, the deformation DIA (D-DIA) to determine the deformation behavior of a number of important upper mantle rock types including olivine, garnet, enstatite, and periclase. Experiments were carried out under both hydrous and anhydrous conditions and at both lithospheric and asthenospheric stress and temperature conditions. The result was a group of flow laws for Earth’s upper mantle that quantitatively describe the viscosity of mantle rocks from shallow depths (the lithosphere) to great depths (the asthenosphere). These flow laws are fundamental for modeling the geodynamic behavior and heat transport from depth to Earth’s surface.

  3. Is There a Temperate Bias in Our Understanding of How Climate Change Will Alter Plant-Herbivore Interactions? A Meta-analysis of Experimental Studies. (United States)

    Mundim, Fabiane M; Bruna, Emilio M


    Climate change can drive major shifts in community composition and interactions between resident species. However, the magnitude of these changes depends on the type of interactions and the biome in which they take place. We review the existing conceptual framework for how climate change will influence tropical plant-herbivore interactions and formalize a similar framework for the temperate zone. We then conduct the first biome-specific tests of how plant-herbivore interactions change in response to climate-driven changes in temperature, precipitation, ambient CO2, and ozone. We used quantitative meta-analysis to compare predicted and observed changes in experimental studies. Empirical studies were heavily biased toward temperate systems, so testing predicted changes in tropical plant-herbivore interactions was virtually impossible. Furthermore, most studies investigated the effects of CO2 with limited plant and herbivore species. Irrespective of location, most studies manipulated only one climate change factor despite the fact that different factors can act in synergy to alter responses of plants and herbivores. Finally, studies of belowground plant-herbivore interactions were also rare; those conducted suggest that climate change could have major effects on belowground subsystems. Our results suggest that there is a disconnection between the growing literature proposing how climate change will influence plant-herbivore interactions and the studies testing these predictions. General conclusions will also be hampered without better integration of above- and belowground systems, assessing the effects of multiple climate change factors simultaneously, and using greater diversity of species in experiments.

  4. Understanding the origin of photoluminescence in disordered Ca0.60Sr0.40WO4: An experimental and first-principles study

    International Nuclear Information System (INIS)

    Longo, V.M.; Orhan, E.; Cavalcante, L.S.; Porto, S.L.; Espinosa, J.W.M.; Varela, J.A.; Longo, E.


    Visible photoluminescence (PL) was observed for the first time at room temperature in structurally disordered calcium strontium tungstate powder, Ca 0.60 Sr 0.40 WO 4 (CSW), obtained by the polymeric precursor method. The PL behavior of CSW powders has been analyzed as a function of the disorder rate, based on experimental and theoretical studies. Quantum mechanical theory based on density functional theory at the B3LYP level has been employed to study the electronic structure of two periodic models representing both crystalline and disordered powders. Their electronic structures have been analyzed in terms of density of states, band dispersion and charge densities. The calculations indicate a break in symmetry when passing from crystalline to disordered models, creating localized electronic levels above the valence band. Moreover, a negative charge transfer process takes place from the [WO 3 ] cluster to the [WO 4 ] cluster. The polarization induced by the break in symmetry and the existence of localized levels favors the creation of trapped holes and electrons, originating the PL phenomenon

  5. Relation between "terra rossa" from the Apulia aquifer of Italy and the radon content of groundwater: Experimental results and their applicability to radon occurrence in the aquifer (United States)

    Tadolini, T.; Spizzico, M.

    The radon-222 (222Rn) activity in groundwater of the Apulian karstic aquifer in southern Italy is as great as 500 Becquerel per liter (Bq/L) locally. Normal radium-226 (226Ra) activity in the limestone and calcareous dolomites of the aquifer is not enough to explain such a high level. Laboratory investigations identified high 226Ra activity in the "terra rossa," the residuum occupying fissures and cavities in the bedrock, and also the relation between (1) 226Ra-bearing bedrock and "terra rossa" and (2) 222Rn in water. The "terra rossa" is the primary source of the radon in the groundwater. The experimental results show the need to characterize the "terra rossa" of Apulia on the basis of 226Ra activity and also to study the distribution and variations in 222Rn activity over time in the aquifer. Résumé L'activité du radon-222 (222Rn) dans les eaux souterraines de l'aquifère karstique des Pouilles, dans le sud de l'Italie, atteint localement 500 Becquerel par litre (Bq/L). L'activité normale du radium-226 (226Ra) dans les calcaires et dans les calcaires dolomitiques de l'aquifère n'est pas assez élevée pour expliquer des valeurs aussi élevées. Des analyses de laboratoire ont mis en évidence une forte activité en 226Ra dans la terra rossa, remplissage de fissures et de cavités de la roche, ainsi qu'une relation entre (1) la roche et la terra rossa contenant du 226Ra et (2) le 222Rn dans l'eau. La terra rossa est la source primaire de radon dans l'eau souterraine. Les résultats expérimentaux montrent qu'il est nécessaire de caractériser la terra rossa des Pouilles par son activité en 226Ra et d'étudier la distribution et les variations de l'activité en 222Rn au cours du temps dans l'aquifère. Resumen La actividad del radon-222 (222Rn) en el agua subterránea del acuífero cárstico de Apulia, al sur de Italia, alcanza localmente los 500Bq/L. La actividad normal del radio-226 (226Ra) en las calcitas y dolomitas del acuífero no es suficiente para

  6. Trends in animal experimentation. (United States)

    Monteiro, Rosangela; Brandau, Ricardo; Gomes, Walter J; Braile, Domingo M


    The search of the understanding of etiological factors, mechanisms and treatment of the diseases has been taking to the development of several animal models in the last decades. To discuss aspects related to animal models of experimentation, animal choice and current trends in this field in our country. In addition, this study evaluated the frequency of experimental articles in medical journals. Five Brazilian journals indexed by LILACS, SciELO, MEDLINE, and recently incorporate for Institute for Scientific Information Journal of Citation Reports were analyzed. All the papers published in those journals, between 2007 and 2008, that used animal models, were selected based on the abstracts. Of the total of 832 articles published in the period, 92 (11.1%) experimentation papers were selected. The number of experimental articles ranged from 5.2% to 17.9% of the global content of the journal. In the instructions to the authors, four (80%) journals presented explicit reference to the ethical principles in the conduction of studies with animals. The induced animal models represented 100% of the articles analyzed in this study. The rat was the most employed animal in the analyzed articles (78.3%). The present study can contribute, supplying subsidies for adoption of future editorials policies regarding the publication of animal research papers in Brazilian Journal of Cardiovascular Surgery.

  7. Experimental practice using 3D scanning for understanding the structure of a stone chamber from the Kofun period, Japan – A case study of the Shobuzako Kofun, Okayama prefecture –

    Directory of Open Access Journals (Sweden)

    Yuji Yamaguchi


    Full Text Available The Shobuzako Kofun, located in Okayama prefecture (western Japan, is a key-hole tomb set on a low rolling hill dating to the 5th century AD. Its stone chamber and burial goods are in very good condition because the stone chamber has not been looted. In this presentation, we will indicate a case study of the experimental use of 3D measuring techniques for recording and understanding the structure of a stone chamber, as well as the layout of burial goods’ layers in the Shobuzako Kofun. We will show some of the benefits and problems of 3D measuring techniques, and the basic remarks for using this method.

  8. Content Marketing


    Le, Duc


    The purpose of this thesis was to introduce the new trend in today’s marketing world: content marketing. It has been employed by many companies and organizations in the world and has been proven success even when it is still a fairly new topic. Five carefully selected theories of content marketing proposed by experts in the field has been collected, compared and displayed as originally and scientifically as possible in this thesis. The chosen theories provide a diversified perspectives of...

  9. Understanding Carbohydrates (United States)

    ... Size: A A A Listen En Español Understanding Carbohydrates How much and what type of carbohydrate foods ... glucose levels in your target range. Explore: Understanding Carbohydrates Glycemic Index and Diabetes Learn about the glycemic ...

  10. Local Content

    CSIR Research Space (South Africa)

    Gibberd, Jeremy


    Full Text Available , 1997; Qiu & Tao, 2001; Corkin, 2012; Warner, 2011; Stephenson, 2013). Local content is also seen a way of improving national sustainability performance and developing greener buildings (Olivier et al, 2016; van Reneen, 2014; Gibberd, 2002). As a result...

  11. Data content standards in Africa

    CSIR Research Space (South Africa)

    Cooper, Antony K


    Full Text Available Data content standards tend to be more accessible. Easier to understand. Used directly by many end users. Immediately applicable to Africa. More susceptible to culture and language – Hence, more important to have local standards...

  12. Understanding classification

    NARCIS (Netherlands)

    Subianto, M.


    In practical data analysis, the understandability of models plays an important role in their acceptance. In the data mining literature, however, understandability plays is hardly ever mentioned. If it is mentioned, it is interpreted as meaning that the models have to be simple. In this thesis we

  13. Qualitative Content Analysis

    Directory of Open Access Journals (Sweden)

    Satu Elo


    Full Text Available Qualitative content analysis is commonly used for analyzing qualitative data. However, few articles have examined the trustworthiness of its use in nursing science studies. The trustworthiness of qualitative content analysis is often presented by using terms such as credibility, dependability, conformability, transferability, and authenticity. This article focuses on trustworthiness based on a review of previous studies, our own experiences, and methodological textbooks. Trustworthiness was described for the main qualitative content analysis phases from data collection to reporting of the results. We concluded that it is important to scrutinize the trustworthiness of every phase of the analysis process, including the preparation, organization, and reporting of results. Together, these phases should give a reader a clear indication of the overall trustworthiness of the study. Based on our findings, we compiled a checklist for researchers attempting to improve the trustworthiness of a content analysis study. The discussion in this article helps to clarify how content analysis should be reported in a valid and understandable manner, which would be of particular benefit to reviewers of scientific articles. Furthermore, we discuss that it is often difficult to evaluate the trustworthiness of qualitative content analysis studies because of defective data collection method description and/or analysis description.

  14. Embodied understanding. (United States)

    Johnson, Mark


    Western culture has inherited a view of understanding as an intellectual cognitive operation of grasping of concepts and their relations. However, cognitive science research has shown that this received intellectualist conception is substantially out of touch with how humans actually make and experience meaning. The view emerging from the mind sciences recognizes that understanding is profoundly embodied, insofar as our conceptualization and reasoning recruit sensory, motor, and affective patterns and processes to structure our understanding of, and engagement with, our world. A psychologically realistic account of understanding must begin with the patterns of ongoing interaction between an organism and its physical and cultural environments and must include both our emotional responses to changes in our body and environment, and also the actions by which we continuously transform our experience. Consequently, embodied understanding is not merely a conceptual/propositional activity of thought, but rather constitutes our most basic way of being in, and engaging with, our surroundings in a deep visceral manner.

  15. Real time release testing of tablet content and content uniformity. (United States)

    Goodwin, Daniel J; van den Ban, Sander; Denham, Mike; Barylski, Ian


    A comprehensive commercial control strategy for tablet content and content uniformity focussed on the unit operation of compression is presented and is proposed to enable real time release for these critical quality attributes. The control strategy is based on process understanding, process control through compaction force weight control on the tablet press, periodic checks of mean and individual tablet weight combined with at-line testing of tablet content by near infrared (NIR). The application of the at-line NIR tablet content method is discussed and an acceptance criteria based on a parametric tolerance interval test (PTIT) is proposed. Sample handling limitations and spectral acquisition time for the NIR content method limit the sample size, however the chosen PTIT assures an appropriate level of batch coverage. Data are presented for ten commercial-scale batches that demonstrates the control strategy delivered the quality standard for content and content uniformity. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Content Analysis

    Directory of Open Access Journals (Sweden)

    George Bedinelli Rossi


    Full Text Available This study introduces the various definitions and types of content analysis. This type of analysis historically presents itself as a quantitative approach to data analysis and currently shows up as a qualitative approach. The most common types are the conceptual and relational analysis. The latter receives influences of linguistic, cognitive and mental models and it is subdivided in affective extraction, analysis of proximity and cognitive mapping. Regarding the importance of this type of analysis, we have quantitative and qualitative character and the latter approach can be used to identify hypotheses, theoretical constructs or even models that can be tested by multivariate statistical techniques or even by experiments. 

  17. Understanding Pregnancy and Birth Issues (United States)

    ... Home Current Issue Past Issues Understanding Pregnancy and Birth Issues Past Issues / Winter 2008 Table of Contents ... about NICHD preeclampsia research in the sidebar.) Preterm Birth Preterm (premature) birth is birth before the baby ...

  18. Understanding semantics

    DEFF Research Database (Denmark)

    Thrane, Torben


    Understanding natural language is a cognitive, information-driven process. Discussing some of the consequences of this fact, the paper offers a novel look at the semantic effect of lexical nouns and the identification of reference types....

  19. Understanding homelessness


    Somerville, Peter


    This paper reviews the literature on understanding homelessness. It criticizes approaches that ignore, distort or diminish the humanity of homeless people, or else, add little to our understanding of that humanity. In particular, it rejects what it calls “epidemiological” approaches, which deny the possibility of agency for homeless people, insofar as those approaches view the situation of those people largely as a “social fact”, to be explained in terms of causal variables or “risk factors” ...

  20. Making sense of early false-belief understanding. (United States)

    Helming, Katharina A; Strickland, Brent; Jacob, Pierre


    We address the puzzle about early belief ascription: young children fail elicited-response false-belief tasks, but they demonstrate spontaneous false-belief understanding. Based on recent converging evidence, we articulate a pragmatic framework to solve this puzzle. Young children do understand the contents of others' false belief, but they are overwhelmed when they must simultaneously make sense of two distinct actions: the instrumental action of a mistaken agent and the experimenter's communicative action. Copyright © 2014 Elsevier Ltd. All rights reserved.

  1. The role of content marketing in social media content communities

    Directory of Open Access Journals (Sweden)

    Charmaine du Plessis


    Full Text Available Background: Content marketing has become a leading marketing technique in digital marketing communication and uses the point of view of consumers to build relationships by creating and sharing engaging content in social media that enhance their daily lives. Existing research on social media communities has focused mainly on social media marketing and virtual brand community perspectives while content marketing’s valuable and unobtrusive role in social media content communities has largely been overlooked. Objective: The purpose of this article was to investigate content marketing’s role in social media content communities to engage with the target audience in an innate manner. Method: This study made use of a directed, inductive content analysis of 51 practitioner documents relating to business-to-consumer content marketing practices to add another perspective to existing research on communities in social media. The content analysis was facilitated by using QDA Miner, a widely adopted and reliable qualitative data analysis software programme. Results: Three categories emerged from the data namely building content communities, platform-specific content and understanding channels. These categories provide sufficient evidence of how brands make use of social media content communities to connect with the target audience in an unobtrusive manner, in addition to being present in virtual brand communities. Conclusion: The findings make several contributions to the existing literature. Firstly, it provides a clearer distinction between brand and social media content communities. Secondly, it extends conceptions about social media communities to include content communities and, thirdly, it provides sufficient evidence of how content marketing could benefit a brand by naturally becoming part of social media conversations.

  2. Understanding Maple

    CERN Document Server

    Thompson, Ian


    Maple is a powerful symbolic computation system that is widely used in universities around the world. This short introduction gives readers an insight into the rules that control how the system works, and how to understand, fix, and avoid common problems. Topics covered include algebra, calculus, linear algebra, graphics, programming, and procedures. Each chapter contains numerous illustrative examples, using mathematics that does not extend beyond first-year undergraduate material. Maple worksheets containing these examples are available for download from the author's personal website. The book is suitable for new users, but where advanced topics are central to understanding Maple they are tackled head-on. Many concepts which are absent from introductory books and manuals are described in detail. With this book, students, teachers and researchers will gain a solid understanding of Maple and how to use it to solve complex mathematical problems in a simple and efficient way.

  3. Understanding physics

    CERN Document Server

    Mansfield, Michael


    Understanding Physics - Second edition is a comprehensive, yet compact, introductory physics textbook aimed at physics undergraduates and also at engineers and other scientists taking a general physics course. Written with today's students in mind, this text covers the core material required by an introductory course in a clear and refreshing way. A second colour is used throughout to enhance learning and understanding. Each topic is introduced from first principles so that the text is suitable for students without a prior background in physics. At the same time the book is designed to enable

  4. Understanding Energy (United States)

    Menon, Deepika; Shelby, Blake; Mattingly, Christine


    "Energy" is a term often used in everyday language. Even young children associate energy with the food they eat, feeling tired after playing soccer, or when asked to turn the lights off to save light energy. However, they may not have the scientific conceptual understanding of energy at this age. Teaching energy and matter could be…

  5. Experimental determination of dissolved CO2 content in nominally anhydrous andesitic melts at graphite/diamond saturation - Remobilization of deeply subducted reduced carbon via partial melts of MORB-like eclogite (United States)

    Eguchi, J.; Dasgupta, R.


    Experimental phase relations of carbonated lithologies [1] and geochemistry of deep diamonds [2] suggest that deep recycling of carbon has likely been efficient for a significant portion of Earth's history. Both carbonates and organic carbon subduct into the mantle, but with gradual decrease of fO2 with depth [3] most carbon in deep mantle rocks including eclogite could be diamond/graphite [4]. Previous studies investigated the transfer of CO2 from subducted eclogite to the ambient mantle by partial melting in the presence of carbonates, i.e., by generation of carbonate-rich melts [5]. However, the transfer of carbon from subducted eclogite to the mantle can also happen, perhaps more commonly, by extraction of silicate partial melt in the presence of reduced carbon; yet, CO2 solubility in eclogite-derived andesitic melt at graphite/diamond saturation remains unconstrained. CO2content of eclogite melts is also critical as geochemistry of many ocean island basalts suggest the presence of C and eclogite in their source regions [6]. In the present study we determine CO2 concentration in a model andesitic melt [7] at graphite/diamond saturation at conditions relevant for partial melting of eclogite in the convecting upper mantle. Piston cylinder and multi anvil experiments were conducted at 1-6 GPa and 1375-1550 °C using Pt/Gr double capsules. Oxygen fugacity was monitored with Pt-Fe sensors in the starting mix. Completed experiments at 1-3 GPa show that CO2 concentration increases with increasing P, T, and fO2 up to ~0.3 wt%. Results were used to develop empirical and thermodynamic models to predict CO2 concentration in partial melts of graphite saturated eclogite. This allowed us to quantify the extent to which CO2 can mobilize from eclogitic heterogeneities at graphite/diamond saturated conditions. With estimates of eclogite contribution to erupted basaltic lavas, the models developed here allow us to put constraints on the flux of CO2 to mantle source regions

  6. Experimental thermomechanical damage as first approach to understand the petrophysical behavior of the granitic host-rocks from an active fractured-geothermal system (Liquiñe, Chile - 39º S) (United States)

    Molina Piernas, E.; Sepúlveda, J.; Arancibia, G.; Roquer, T.; Morata, D.; Bracke, R.; Vázquez, P.


    Chile's location along an active subduction zone has endowed it with a high geothermal potential. However, a better understanding of the thermomechanical and fluid transport properties of rocks is required to assess the potential of geothermal systems and thereby enhance the possibilities for their use. We have focused in the area surrounding Liquiñe, in the Southern Andean Volcanic Zone (Chile, 39º S). This area hosts several recent thermal manifestations, predominantly hot springs, and it is affected by the Liquiñe-Ofqui Fault Zone (LOFZ), which controls the position of the modern volcanic arc in southern Chile and cuts the Patagonian batholith. We have carried out experimental analyzes in order to understand this geothermal system and the influence of the thermomechanical features over the granitic host-rocks (low-porous crystalline rocks). To do this, physical properties such as capillary water absorption coefficient, Vp-wave velocity and compressive resistance were evaluated before and after heating rock samples at 150 ºC and 210 ºC (at ambient pressure) in an oven at a heating rate of 6 °C/min and maintaining the maximum temperature for 4 hours. The cooling rate was less than 2 °C/min to avoid shrinkage phenomena. The results show that the damage by heat was greater at 210 ºC than 150 ºC, likely due to an increased capillary coefficient ( 30% and 25%). On the contrary, Vpvelocity ( -19% and -13%) and compressive resistance ( -27% in both cases) decreased, with respect to unheated samples. Consequently, we can infer an inherent effect on the later fracture process due to the thermal stress when this granitic body was at depth. After that, and considering the local and regional strain-stress state, both factors have facilitated the fluid flow, increasing the permeability of this granitic host-rock allowing the presence of hot-springs. Future work will be to acquire complementary petrophysical parameters, such as porosity, permeability, thermal

  7. Understanding translation

    DEFF Research Database (Denmark)

    Schjoldager, Anne Gram; Gottlieb, Henrik; Klitgård, Ida

    Understanding Translation is designed as a textbook for courses on the theory and practice of translation in general and of particular types of translation - such as interpreting, screen translation and literary translation. The aim of the book is to help you gain an in-depth understanding...... of the phenomenon of translation and to provide you with a conceptual framework for the analysis of various aspects of professional translation. Intended readers are students of translation and languages, but the book will also be relevant for others who are interested in the theory and practice of translation...... - translators, language teachers, translation users and literary, TV and film critics, for instance. Discussions focus on translation between Danish and English....

  8. Understanding Resilience

    Directory of Open Access Journals (Sweden)

    Gang eWu


    Full Text Available Resilience is the ability to adapt successfully in the face of stress and adversity. Stressful life events, trauma and chronic adversity can have a substantial impact on brain function and structure, and can result in the development of PTSD, depression and other psychiatric disorders. However, most individuals do not develop such illnesses after experiencing stressful life events, and are thus thought to be resilient. Resilience as successful adaptation relies on effective responses to environmental challenges and ultimate resistance to the deleterious effects of stress, therefore a greater understanding of the factors that promote such effects is of great relevance. This review focuses on recent findings regarding genetic, epigenetic, developmental, psychosocial and neurochemical factors that are considered essential contributors to the development of resilience. Neural circuits and pathways involved in mediating resilience are also discussed. The growing understanding of resilience factors will hopefully lead to the development of new pharmacological and psychological interventions for enhancing resilience and mitigating the untoward consequences.

  9. Experimental electron density studies as key for understanding the chemical and physical properties in selected model systems; Experimentelle Elektronendichtestudien als Schluessel zum Verstaendnis chemischer und physikalischer Eigenschaften in ausgewaehlten Modellsystemen

    Energy Technology Data Exchange (ETDEWEB)

    Hauf, Christoph


    The topological analysis of experimentally determined electron density distributions, employing the quantum theory of atoms in molecules developed by Richard FW Bader, was used in this thesis to study chemically or physically motivated questions in appropriate model systems. First, transition metal complexes with activated C-H bonds or Si-H bonds were examined which led to a better understanding of agostic interactions. An important tool during these investigations is the so called atomic graph, which describes the characteristic spatial arrangement of the critical points of the Laplacefield of the electron density distribution in the valence shell of the relevant atoms. It reveals zones with a locally concentrated or depleted electron density distribution. This leads to the empirical rule, that a strong activation of C-H bonds or Si-H bonds is only observed when the hydrogen atom faces a pronounced charge depletion zone at the transition metal atom. In addition, the quasi one-dimensional rare-earth transition metal carbides Sc{sub 3}FeC{sub 4}, Sc{sub 3}CoC{sub 4} and Sc{sub 3}NiC{sub 4} were examined. Although all three compounds are isotypic at room temperature, it was revealed during this thesis, that only Sc{sub 3}CoC{sub 4} undergoes a structural phase transition at a temperature of ∝ 70 K and becomes superconducting below a critical temperature of 4.5 K. The main reason for this behaviour is the variation of the valence electrons through the exchange of Fe by Co or Ni. This results in the occupation of progressively higher energy electronic states and a raising of the Fermi level. The change in the nature of the electronic states at the Fermi level is in turn reflected by the different atomic graphs of the transition metal atoms and the distinct physical properties of these three compounds.

  10. Understand electronics

    CERN Document Server

    Bishop, Owen


    Understand Electronics provides a readable introduction to the exciting world of electronics for the student or enthusiast with little previous knowledge. The subject is treated with the minimum of mathematics and the book is extensively illustrated.This is an essential guide for the newcomer to electronics, and replaces the author's best-selling Beginner's Guide to Electronics.The step-by-step approach makes this book ideal for introductory courses such as the Intermediate GNVQ.

  11. Understanding users

    DEFF Research Database (Denmark)

    Johannsen, Carl Gustav Viggo


    Segmentation of users can help libraries in the process of understanding user similarities and differences. Segmentation can also form the basis for selecting segments of target users and for developing tailored services for specific target segments. Several approaches and techniques have been...... segmentation project using computer-generated clusters. Compared to traditional marketing texts, this article also tries to identify user segments or images or metaphors by the library profession itself....

  12. Understanding unemployment


    Guillaume Rocheteau


    Modern economists have built models of the labor market, which isolate the market’s key drivers and describe the way these interact to produce particular levels of unemployment. One of the most popular models used by macroeconomists today is the search-matching model of equilibrium unemployment. We explain this model, and show how it can be applied to understand the way various policies, such as unemployment benefits, taxes, or technological changes, can affect the unemployment rate.

  13. Understanding Technology?

    Directory of Open Access Journals (Sweden)

    Erik Bendtsen


    Full Text Available We are facing radical changes in our ways of living in the nearest future. Not necessarily of our own choice, but because tchnological development is moving so fast, that it will have still greater impact on many aspects of our lives. We have seen the beginnings of that change within the latest 35 years or so, but according to newest research that change will speed up immensely in the nearest years to come. The impact of that change or these changes will affect our working life immensely as a consequence of automation. How these changes are brought about and which are their consequences in a broad sense is being attempted to be understood and guessed by researchers. No one knows for sure, but specific patterns are visible. This paper will not try to guess, what will come, but will rather try to understand the deepest ”nature” of technology in order to understand the driving factors in this development: the genesis of technology in a broad sense in order to contibute to the understanding of the basis for the expected development.

  14. Estimation of soil clay content from hygroscopic water content measurements


    Wuddivira, Mark N.; Robinson, David A.; Lebron, Inma; Brechet, Laëtitia; Atwell, Melissa; De Caires, Sunshine; Oatham, Michael; Jones, Scott B.; Abdu, Hiruy; Verma, Aditya K.; Tuller, Markus


    Soil texture and the soil water characteristic are key properties used to estimate flow and transport parameters. Determination of clay content is therefore critical for understanding of plot-scale soil heterogeneity. With increasing interest in proximal soil sensing, there is the need to relate obtained signals to soil properties of interest. Inference of soil texture, especially clay mineral content, from instrument response from electromagnetic induction and radiometric methods is of subst...

  15. Understanding uncertainty

    CERN Document Server

    Lindley, Dennis V


    Praise for the First Edition ""...a reference for everyone who is interested in knowing and handling uncertainty.""-Journal of Applied Statistics The critically acclaimed First Edition of Understanding Uncertainty provided a study of uncertainty addressed to scholars in all fields, showing that uncertainty could be measured by probability, and that probability obeyed three basic rules that enabled uncertainty to be handled sensibly in everyday life. These ideas were extended to embrace the scientific method and to show how decisions, containing an uncertain element, could be rationally made.

  16. Understanding analysis

    CERN Document Server

    Abbott, Stephen


    This lively introductory text exposes the student to the rewards of a rigorous study of functions of a real variable. In each chapter, informal discussions of questions that give analysis its inherent fascination are followed by precise, but not overly formal, developments of the techniques needed to make sense of them. By focusing on the unifying themes of approximation and the resolution of paradoxes that arise in the transition from the finite to the infinite, the text turns what could be a daunting cascade of definitions and theorems into a coherent and engaging progression of ideas. Acutely aware of the need for rigor, the student is much better prepared to understand what constitutes a proper mathematical proof and how to write one. Fifteen years of classroom experience with the first edition of Understanding Analysis have solidified and refined the central narrative of the second edition. Roughly 150 new exercises join a selection of the best exercises from the first edition, and three more project-sty...

  17. Understanding ayurveda. (United States)

    Gadgil, Vaidya Dilip


    Ayurveda needs to achieve its full potential both in India and globally. This requires imparting to its students full appreciation of Ayurveda's power and strength, particularly proper understanding of the advantages of applying it to treat chronic and acute diseases. To this end, we explain the necessity of learning Sanskrit as a medium of study, and the advantages of learning the Texts in the traditional way, rather than relying on translations with all the loss of meaning and precision, which that entails. We emphasize the use of Triskandhakosha as a means to fully understand Ayurveda fundamental concepts and technical terms, so that all their shades of meaning are fully understood, and all their usages given in different places in the texts. Only by such methods can full appreciation of Ayurvedic wisdom be achieved, and the full depth and power of its knowledge be applied. Only then will its true status among systems of medicine come to be appreciated, either in India or more widely in the world as a whole.

  18. Understanding Ayurveda

    Directory of Open Access Journals (Sweden)

    Vaidya Dilip Gadgil


    Full Text Available Ayurveda needs to achieve its full potential both in India and globally. This requires imparting to its students full appreciation of Ayurveda′s power and strength, particularly proper understanding of the advantages of applying it to treat chronic and acute diseases. To this end, we explain the necessity of learning Sanskrit as a medium of study, and the advantages of learning the Texts in the traditional way, rather than relying on translations with all the loss of meaning and precision, which that entails. We emphasize the use of Triskandhakosha as a means to fully understand Ayurveda fundamental concepts and technical terms, so that all their shades of meaning are fully understood, and all their usages given in different places in the texts. Only by such methods can full appreciation of Ayurvedic wisdom be achieved, and the full depth and power of its knowledge be applied. Only then will its true status among systems of medicine come to be appreciated, either in India or more widely in the world as a whole.

  19. Is animal experimentation fundamental? (United States)

    d'Acampora, Armando José; Rossi, Lucas Félix; Ely, Jorge Bins; de Vasconcellos, Zulmar Acciolli


    The understanding about the utilization of experimental animals in scientific research and in teaching is many times a complex issue. Special attention needs to be paid to attain the understanding by the general public of the importance of animal experimentation in experimental research and in undergraduate medical teaching. Experimental teaching and research based on the availability of animals for experimentation is important and necessary for the personal and scientific development of the physician-to-be. The technological arsenal which intends to mimic experimentation animals and thus fully replace their use many times does not prove to be compatible with the reality of the living animal. The purpose of this paper is to discuss aspects concerning this topic, bringing up an issue which is complex and likely to arouse in-depth reflections.

  20. Understanding physics

    CERN Document Server

    Cassidy, David; Rutherford, James


    Understanding Physics provides a thorough grounding in contemporary physics while placing physics into its social and historical context Based in large part on the highly respected Project Physics Course developed by two of the authors, it also integrates the results of recent pedagogical research The text thus - teaches about the basic phenomena in the physical world and the concepts developed to explain them - shows that science is a rational human endeavor with a long and continuing tradition, involving many different cultures and people - develops facility in critical thinking, reasoned argumentation, evaluation of evidence, mathematical modeling, and ethical values The treatment emphasizes not only what we know but also how we know it, why we believe it, and what effects that knowledge has - Why do we believe the Earth and planets revolve around the Sun? - Why do we believe that matter is made of atoms? - How do relativity theory and quantum mechanics alter our conception of Nature and in what ways do th...

  1. Superficial tension: experimental model with simple materials

    Directory of Open Access Journals (Sweden)

    Tintori Ferreira, María Alejandra


    Full Text Available In this work appears a didactic offer based on an experimental activity using materials of very low cost, orientated to achieving that the student understand and interpret the phenomenon of superficial tension together with the importance of the modeling in sciences. It has as principal aim of education bring the student over to the mechanics of the static fluids and the intermolecular forces, combining scientific contents with questions near to the student what provides an additional motivation to the reflection of the scientific investigation.

  2. Understanding PISA

    Directory of Open Access Journals (Sweden)

    Stephen DOWNES


    Full Text Available Understanding PISA Stephen DOWNESMoncton, CANADA ABSTRACT The headline was dramatic enough to cause a ripple in the reading public. "Students who use computers a lot at school have worse maths and reading performance," noted the BBC news article, citing a 2004 study by Ludger Woessmann and Thomas Fuchs (Fuchs and Woessman, 2004. It was not long before the blogosphere took notice. Taking the theme and running with it, Alice and Bill ask, "Computers Make School Kids Dumber?" They theorize, "If you track the admitted decline of education, you'll probably notice that it follows along with the increase of technology in the classroom." In a similar vein, James Bartholomew asks, "Do you think that the government will turn down the volume of its boasting about how it has spent billions introducing computers in schools (while keeping down the pay of teachers so much that there are shortages? Do you think it will stop sending governors of state schools glossy pamphlets about insisting that computers are used in their schools as much as possible?" In this study, therefore, PISA looks well beyond educational attainment, and also includes school demographics, such as whether it is a public or private school, has large or small classes, or has access or not to technological resources. Finally, it does measure student information-their family background, access to books and computers and parental support as well. The PISA survey departs from previous surveys in disregarding the stated curricula of the schools being measured. Therefore, the conclusion is not surprising, nor even wrong for him to consider independently of any parental or teacher support, considered without reference to the software running on it, considered without reference to student attitudes and interests, does not positively impact an education. Finally, he focus on missing the reporting of results

  3. The muon content of gamma-ray showers (United States)

    Edwards, P. G.; Protheroe, R. J.


    The result of a calculation of the expected number of muons in gamma ray initiated and cosmic ray initiated air showers using a realistic model of hadronic collisions in an effort to understand the available experimental results and to assess the feasibility of using the muon content of showers as a veto to reject cosmic ray initiated showers in ultra-high energy gamma ray astronomy are reported. The possibility of observing very-high energy gamma-ray sources by detecting narrow angle anisotropies in the high energy muon background radiation are considered.

  4. The effect of immobilization and 3 (beta-aminoethyl)-1, 2, 4 triazol on the calcium content in gastric tissues of guinea pigs during the formation of experimental ulcers (United States)

    Grechishkin, L. L.; Ritling, K.


    A sharp fall in the concentration of calcium in gastric tissues upon immobilization and after administration of the histamine analog was recorded. Similar shifts were seen to occur in the blood plasma as well. This implies that under the effect of different action, tissue dystrophy develops by following a common mechanism involving not only the adenyl cyclase system, but that of calcium ion metabolism as well. The calcium ion content in the blood plasma and gastric tissues were measured by atomic absorption spectrophotometry.

  5. A study of real-time content marketing : formulating real-time content marketing based on content, search and social media


    Nguyen, Thi Kim Duyen


    The primary objective of this research is to understand profoundly the new concept of content marketing – real-time content marketing on the aspect of the digital marketing experts. Particularly, the research will focus on the real-time content marketing theories and how to build real-time content marketing strategy based on content, search and social media. It also finds out how marketers measure and keep track of conversion rates of their real-time content marketing plan. Practically, th...

  6. Multimedia content classification metrics for content adaptation


    Fernandes, Rui; Andrade, M.T.


    Multimedia content consumption is very popular nowadays. However, not every content can be consumed in its original format: the combination of content, transport and access networks, consumption device and usage environment characteristics may all pose restrictions to that purpose. One way to provide the best possible quality to the user is to adapt the content according to these restrictions as well as user preferences. This adaptation stage can be best executed if knowledge about the conten...

  7. Multimedia content classification metrics for content adaptation


    Fernandes, Rui; Andrade, M.T.


    Multimedia content consumption is very popular nowadays. However, not every content can be consumed in its original format: the combination of content, transport and access networks, consumption device and usage environment characteristics may all pose restrictions to that purpose. One way to provide the best possible quality to the user is to adapt the content according to these restrictions as well as user preferences. This adaptation stage can be best executed if knowledge about the conten...

  8. Understanding Ebola Virus Transmission

    Directory of Open Access Journals (Sweden)

    Seth Judson


    Full Text Available An unprecedented number of Ebola virus infections among healthcare workers and patients have raised questions about our understanding of Ebola virus transmission. Here, we explore different routes of Ebola virus transmission between people, summarizing the known epidemiological and experimental data. From this data, we expose important gaps in Ebola virus research pertinent to outbreak situations. We further propose experiments and methods of data collection that will enable scientists to fill these voids in our knowledge about the transmission of Ebola virus.

  9. Understanding quantum phase transitions

    CERN Document Server

    Carr, Lincoln


    Quantum phase transitions (QPTs) offer wonderful examples of the radical macroscopic effects inherent in quantum physics: phase changes between different forms of matter driven by quantum rather than thermal fluctuations, typically at very low temperatures. QPTs provide new insight into outstanding problems such as high-temperature superconductivity and display fundamental aspects of quantum theory, such as strong correlations and entanglement. Over the last two decades, our understanding of QPTs has increased tremendously due to a plethora of experimental examples, powerful new numerical meth

  10. Understanding Teaching beyond Content and Method: Insights from Central Asia (United States)

    Niyozov, Sarfaroz


    This study suggests the need for complex research approaches that provide richer, contested, and nondichotomous portrayals of classrooms, schooling life, and teachers. Drawing from a qualitative study of Tajik teachers' practices and perspectives (Niyozov, 2001) and studies on teaching conducted in Kyrgyzstan (De Young, Reeves, & Valyaeva ,…

  11. Examining Multiple Dimensions of Word Knowledge for Content Vocabulary Understanding (United States)

    Cervetti, Gina N.; Tilson, Jennifer L.; Castek, Jill; Bravo, Marco A.; Trainin, Guy


    This study traces the development of a vocabulary measure designed to assess multiple types of word knowledge. The assessment, which was administered in conjunction with a science unit about weather and the water cycle for third-and-fourth graders, included items for six knowledge types--recognition, definition, classification/example, context,…

  12. Understanding social media use for work : Content, causes, and consequences

    NARCIS (Netherlands)

    van Zoonen, W.


    The multivalent involvement of public social media platforms (e.g., Facebook, Twitter, etc.) in both social and organizational life has raised a number of questions about how, and to what extent and effects organizational members use these technologies for work-related purposes. Yet research has

  13. Teachers’ pedagogical content knowledge and its relation with students’ understanding

    Directory of Open Access Journals (Sweden)



    Full Text Available Realizado un estudio exploratorio respecto de la relación entre el conocimiento de los profesores y la comprensión de los alumnos de cuarto grado, enfocado en la enseñanza de las fracciones. Se examinó el conocimiento del contenido (CK y el conocimiento pedagógico del contenido (PCK de 53 profesores y se cuantificó su experiencia y preparación matemática, así como el nivel socioeconómico y académico de las escuelas en las que se realizó el estudio. Se aplicó una prueba al inicio y otra al término del año escolar a 1.532 alumnos identificando las ganancias y las conquistas de cada grupo en las clases de los profesores. El subcomponente constructivista orientado del CK por parte de los profesores, mostró una asociación significativa con el aprendizaje del alumno, aunque menos significativa que la asociación con la experiencia del profesor. El factor socioeconómico tuvo una fuerte relación con los logros de los alumnos, dejando en evidencia las fuertes diferencias que caracterizan el sistema educativo en Chile.

  14. Understanding the technical content of requirements in specification document

    DEFF Research Database (Denmark)

    Sudin, Mohd Nizam Bin; Ahmed-Kristensen, Saeema


    in practice, 97 statements from 2 specification documents were analyzed in detail and the results are reported in this paper. These statements were analyzed quantitatively and qualitatively based on a pre-defined coding scheme. The results of the study show that the majority of requirements were related...

  15. Educators' Understanding of Workplace Bullying (United States)

    de Wet, Corene


    This article looks at educators' understanding of workplace bullying through the lens of a two- dimensional model of bullying. Educators, who were furthering their studies at the University of the Free State, were invited to take part in a study on different types of bullying. Deductive, directed content analysis was used to analyse 59…

  16. Experimental Design Research

    DEFF Research Database (Denmark)

    This book presents a new, multidisciplinary perspective on and paradigm for integrative experimental design research. It addresses various perspectives on methods, analysis and overall research approach, and how they can be synthesized to advance understanding of design. It explores the foundations...... of experimental approaches and their utility in this domain, and brings together analytical approaches to promote an integrated understanding. The book also investigates where these approaches lead to and how they link design research more fully with other disciplines (e.g. psychology, cognition, sociology...... research practice where methods are diverging and integration between individual, team and organizational understanding is becoming increasingly tenuous, calling for a multidisciplinary and transdiscipinary perspective. Experimental design research thus offers a powerful tool and platform for resolving...

  17. Semantic Borders and Incomplete Understanding. (United States)

    Silva-Filho, Waldomiro J; Dazzani, Maria Virgínia


    In this article, we explore a fundamental issue of Cultural Psychology, that is our "capacity to make meaning", by investigating a thesis from contemporary philosophical semantics, namely, that there is a decisive relationship between language and rationality. Many philosophers think that for a person to be described as a rational agent he must understand the semantic content and meaning of the words he uses to express his intentional mental states, e.g., his beliefs and thoughts. Our argument seeks to investigate the thesis developed by Tyler Burge, according to which our mastery or understanding of the semantic content of the terms which form our beliefs and thoughts is an "incomplete understanding". To do this, we discuss, on the one hand, the general lines of anti-individualism or semantic externalism and, on the other, criticisms of the Burgean notion of incomplete understanding - one radical and the other moderate. We defend our understanding that the content of our beliefs must be described in the light of the limits and natural contingencies of our cognitive capacities and the normative nature of our rationality. At heart, anti-individualism leads us to think about the fact that we are social creatures, living in contingent situations, with important, but limited, cognitive capacities, and that we receive the main, and most important, portion of our knowledge simply from what others tell us. Finally, we conclude that this discussion may contribute to the current debate about the notion of borders.

  18. Understanding climatic change

    International Nuclear Information System (INIS)

    Fellous, J.L.; Gautier, C.; Andre, J.C.; Balstad, R.; Boucher, O.; Brasseur, G.; Chahine, M.T.; Chanin, M.L.; Ciais, P.; Corell, W.; Duplessy, J.C.; Hourcade, J.C.; Jouzel, J.; Kaufman, Y.J.; Laval, K.; Le Treut, H.; Minster, J.F.; Moore, B. III; Morel, P.; Rasool, S.I.; Remy, F.; Smith, R.C.; Somerville, R.C.J.; Wood, E.F.; Wood, H.; Wunsch, C.


    Climatic change is gaining ground and with no doubt is stimulated by human activities. It is therefore urgent to better understand its nature, importance and potential impacts. The chapters of this book have been written by US and French experts of the global warming question. After a description of the Intergovernmental Panel on Climate Change (IPCC, GIEC in French) consensus, they present the past and present researches on each of the main component of the climate system, on the question of climatic change impacts and on the possible answers. The conclusion summarizes the results of each chapter. Content: presentation of the IPCC; greenhouse effect, radiation balance and clouds; atmospheric aerosols and climatic change; global water cycle and climate; influence of climatic change on the continental hydrologic cycle; ocean and climate; ice and climate; global carbon cycle; about some impacts of climatic change on Europe and the Atlantic Ocean; interaction between atmospheric chemistry and climate; climate and society, the human dimension. (J.S.)

  19. Non-destructive determination of moisture content and micro-fibril angle of wood using a poly-chromatic X-ray beam theoretical and experimental approach; Exploitation d'un rayonnement X poly-energetique pour la determination de la teneur en eau et de l'angle de microfibrilles du bois: approche theorique et experimentale

    Energy Technology Data Exchange (ETDEWEB)

    Baettig, R


    Non-destructive determination of moisture content and micro-fibril angle are important stakes for the sciences of the wood because these two parameters influence strongly the macroscopic behavior of the wood. For example, the shrinkage, the mechanical properties, the thermal and acoustic conductivity are dependent on the moisture content and their anisotropic character is largely governed by the micro-fibril angle. We used the light difference between X-ray mass attenuation coefficient for the water and for the wood in transmission. Regrettably, the results show that this difference between X-ray mass attenuation coefficient is insufficient to allow the precise measurement of the moisture content.In spite of this, the coherent scattering shows sensitive effects. So, by using a poly-energetic beam and a spectrometric system, we were able to discriminate between the crystalline constituent (cellulose) of the amorphous constituent (water) in a sample of wet wood, because for a given angle these phases scatter in different energy. Besides, the device created allowed us to study the crystalline phase of the wood. We were able to confront experimental profiles of diffraction with theoretical profiles of diffraction, obtained by means of a rigorous simulation, in the objective to estimate the average micro-fibril angle and its standard deviation. (author)

  20. An Experimental Study

    African Journals Online (AJOL)

    The Role of the Learner's Native Culture in EFL Dictionaries: An Experimental Study. 567 strued. Many studies in ... that nativize texts have found that cultural familiarity (i.e. making use of the students' prior cultural ..... edge) when confronted with new information (in this case, when trying to understand the meaning of new ...

  1. Computational fluid dynamics and experimental tests helping to understand the gravel pack displacement in petroleum wells; Fluidodinamica computacional (CFD) e testes experimentais ajudam a compreender o fenomeno do deslocamento do gravel pack em pocos de petroleo

    Energy Technology Data Exchange (ETDEWEB)

    Magalhaes, Joao Vicente Martins de; Leal, Rafael Amorim Ferreira; Martins, Andre Leibsohn; Calderon, Agostinho; Ferreira, Marcus Vinicius Duarte [Petrobras S.A., Rio de Janeiro, RJ (Brazil)], E-mails:,,,,; Simoes, Bruno; Barbosa, Diego [Halliburton, Novo Cavaleiros, Macae, RJ (Brazil)], E-mails:,


    In the petroleum exploitation and production in deep water, at the fields operated by PETROBRAS, Brazil, one of the problems frequently found is the need of elimination of sand production, having in mind that the most of those fields produce from the non consolidated sandstones. The opened well Gravel Packing is the technique most used for that task. Due to the fact of Gravel Packing operations occurs at thousand of meters below the surface, it is necessary the computational simulation for forecasting how particle deposition (Gravel) in the well occurs. So, it was used the commercial pack of fluid dynamics FLUENT 12, which calculates the fluid velocity field, coupled to another commercial pack, the EDEM, based on discrete elements that treat of particle mechanics. The coupling of the two software has shown adequate the comparison of the computational results with the experimental data shows a good adjustment. Besides, it was possible to simulate problems of well early clogging, showing that the computational simulation is strong and capable of captivating such a phenomena.

  2. Child's understanding of television programmes

    Directory of Open Access Journals (Sweden)

    Martina Peštaj


    Full Text Available In the last decade, we have witnessed an unimaginable progress of the electronic media. The television takes the first place by its availability, importance and popularity, both with adults and with children. It has become the focal point of family interaction and is progressively taking on a key role in the process of children's socialization. Various research has proven that children begin watching television as babies and that toddlers are already accustomed and constant viewers. During their development, they become increasingly competent to understand and to use the television media, while the differences in the perception of television contents are mainly conditioned by the period of early childhood. The process of preschool child's understanding of media information goes from concrete to abstract and on two levels at the same time: understanding of formal features and understanding of content. Both levels have important role in child's understanding of the world, what could be observed in forming of gender stereotypes, where, as researches show, the television has a special influence.

  3. Educators' understanding of workplace bullying


    Corene de Wet


    This article looks at educators' understanding of workplace bullying through the lens o a two-dimensional model of bullying. Educators, who were furthering their studies at the University of the Free State, were invited to take part in a study on different types of bullying. Deductive, directed content analysis was used to analyse 59 participants' descriptions of workplace bullying. The study found that the theoretical model provided a valuable framework for studying bullying in this context....

  4. Shape understanding system machine understanding and human understanding

    CERN Document Server

    Les, Zbigniew


    This is the third book presenting selected results of research on the further development of the shape understanding system (SUS) carried out by authors in the newly founded Queen Jadwiga Research Institute of Understanding. In this book the new term Machine Understanding is introduced referring to a new area of research aiming to investigate the possibility of building machines with the ability to understand. It is presented that SUS needs to some extent mimic human understanding and for this reason machines are evaluated according to the rules applied for the evaluation of human understanding. The book shows how to formulate problems and how it can be tested if the machine is able to solve these problems.    

  5. Dietary small molecules and large-scale gene expression studies: an experimental approach for understanding their beneficial effects on the development of malignant and non-malignant proliferative diseases. (United States)

    Mariappan, Devi; Winkler, Johannes; Parthiban, Vijaya; Doss, Michael Xavier; Hescheler, Jürgen; Sachinidis, Agapios


    Epidemiological studies have repeatedly demonstrated a correlation between nutrition, development and the severity of malignant and non-malignant proliferative diseases such as cancer and atherosclerosis. Therefore, the prevention of chronic proliferative diseases through dietary intervention is currently receiving considerable attention. Until now, much of the research is being focused on the cellular and molecular action mechanisms of dietary small molecules explaining their beneficial effects. Dietary chemicals may affect gene expression in several human diseases. However, significant progress has been made and several molecular action mechanisms have been proposed. Alteration of genetical pathways by nutrition, also called "Nutrigenomics", may offer a new approach for understanding the beneficial effects of dietary compounds on the development of severe polygenic diseases, such as cardiovascular disease, diabetes and hypertension. This review focuses on the nutritional genomics of dietary chemicals with a special emphasis on catechins. Catechins belong to the flavonoid family, which are polyphenolic compounds available in foods of plant origin. Several epidemiological studies have reported that consumption of flavonoids, and especially catechins might function as chemopreventive agents against cancer and cardiovascular diseases.

  6. 臺灣中小學奈米科技實驗教材之內容分析 Content Analysis of Nanotechnology Experimental Teaching Materials in Primary and Secondary Schools in Taiwan

    Directory of Open Access Journals (Sweden)

    趙毓圻 Yu-Chi Chao


    Full Text Available 本研究旨在探究奈米國家型第一期人才培育計畫(2003至2008年)中小學種子教師自主發展的實驗教材所含有的奈米科技重要概念的出現頻率和關聯性。樣本包含209 份教材,以Stevens、Sutherland 與Krajcik(2009)提出的九項奈米尺度科學與工程重要概念:尺寸與尺度、物質構造、尺寸效應、力與交互作用、量子效應、自組裝、工具與儀器、模型與模擬、科學、科技與社會等為分析類目,首先依照各重要概念的定義,編製「奈米科技關鍵詞彙表」,並使用Excel 計數功能,分析國小、國中和高中各學習年段教材中的重要概念出現頻率和關聯性。研究結果發現:各年段中,高中實驗教材含有的奈米科技關鍵詞彙數量最多,且各重要概念間呈現高關聯性;整體中小學實驗教材的各重要概念出現頻率和相互關聯性的結構裡,以「尺寸與尺度」、「物質構造」和「尺寸效應」呈高出現頻率及高關聯性。本研究結果可作為未來建構臺灣中小學奈米科技課程指標,以及發展奈米科技教材之參考。 This study investigates the occurrence and relationships among significant nanotechnology concepts employed in the experimental teaching materials developed by primary and secondary seed teachers during Phase I of the National Science and Technology Program in Nanotechnology (2003 to 2008. This study adopts the core principles or “big ideas” of nanoscale science and engineering education, namely size and scale, structure of matter, forces and interactions, quantum effects, size-dependent properties, self-assembly, tools and instruments, models and simulations, and science, technology, and society (Stevens, Sutherland, & Krajcik, 2009, to compile a checklist of scientific terms in nine dimensions, and uses Microsoft Excel to analyze 209 teaching materials from each educational level. The

  7. Investigation of the supercritical CO2 cycle: mapping of the thermodynamic potential for different applications; further understanding of the physical processes, in particular through simulations and analysis of experimental data

    International Nuclear Information System (INIS)

    Pham, Hong-Son


    The supercritical CO 2 (sc-CO 2 ) cycle has been gaining an increasing attention in the engineering world as an alternative to the Rankine steam cycle. Indeed, it provides high efficiency and allows for compact footprint and simple system layout. This study aims to contribute to the research and development on this cycle; the thermodynamic potential and the physical processes, in particular those related to the real gas behavior of the working fluid near its critical point, are considered. The first part of the thesis reports the mapping of the thermodynamic performance of the sc-CO 2 cycle in a 250 - 850 C TIT (Turbine Inlet Temperature) range, for different configurations. These data provide a preliminary guideline to the maximum performance and inter-linked constraints when coupling the cycle to a specific application. Following this generic study, the cycle has been investigated at TITs of 275 and 515 C for SMR (Small Modular Reactor) and SFR (Sodium-cooled Fast Reactor) applications, respectively, to encompass their specific requirements. The recompression cycle in condensing mode has been identified as the most interesting option in both cases. For the SFR, it achieves an attractive thermal efficiency of 45.7% while keeping the IHX (Intermediate Heat exchanger) inlet temperature below 330 C, as currently considered for this application. The study subsequently addresses the performance and operation of the sc-CO 2 compressor by means of CFD simulations. First, numerical results on a small scale compressor - implemented in a sc-CO 2 compression test loop - have been confronted with the experimental data, highlighting the implications of the measurement uncertainty on the reliability of the compressor performance. Nonetheless, a very good agreement has been achieved regarding the compressor inlet and outlet temperatures and pressures, supporting a first qualification of the CFD technique. Simulations on a real scale compressor - designed for the SMR application

  8. Understanding Food Allergy | NIH MedlinePlus the Magazine (United States)

    ... issue contents Understanding Food Allergy Follow us Understanding Food Allergy Latest Updates from NIH Food allergies are often ... ways to diagnose, prevent, and treat the disease.” Food allergy studies With so many unanswered questions surrounding food ...

  9. Wave liquefaction in soils with clay content

    DEFF Research Database (Denmark)

    Kirca, Özgür; Sumer, B. Mutlu; Fredsøe, Jørgen


    The paper presents the results of an experimental study of the influence of clay content (in silt-clay and sand-clay mixtures) on liquefaction beneath progressive waves. The experiments showed that the influence of clay content is very significant. Susceptibility of silt to liquefaction...... is increased with increasing clay content, up to 30%, beyond which the mixture of silt and clay is not liquefied. Sand may become prone to liquefaction with the introduction of clay, contrary to the general perception that this type of sediment is normally liquefaction resistant under waves....

  10. Experimental philosophy. (United States)

    Knobe, Joshua; Buckwalter, Wesley; Nichols, Shaun; Robbins, Philip; Sarkissian, Hagop; Sommers, Tamler


    Experimental philosophy is a new interdisciplinary field that uses methods normally associated with psychology to investigate questions normally associated with philosophy. The present review focuses on research in experimental philosophy on four central questions. First, why is it that people's moral judgments appear to influence their intuitions about seemingly nonmoral questions? Second, do people think that moral questions have objective answers, or do they see morality as fundamentally relative? Third, do people believe in free will, and do they see free will as compatible with determinism? Fourth, how do people determine whether an entity is conscious?

  11. Qualitative Content Analysis


    Philipp Mayring


    The article describes an approach of systematic, rule guided qualitative text analysis, which tries to preserve some methodological strengths of quantitative content analysis and widen them to a concept of qualitative procedure. First the development of content analysis is delineated and the basic principles are explained (units of analysis, step models, working with categories, validity and reliability). Then the central procedures of qualitative content analysis, inductive development of ca...

  12. Experimental Design Research

    DEFF Research Database (Denmark)

    This book presents a new, multidisciplinary perspective on and paradigm for integrative experimental design research. It addresses various perspectives on methods, analysis and overall research approach, and how they can be synthesized to advance understanding of design. It explores the foundations...... of experimental approaches and their utility in this domain, and brings together analytical approaches to promote an integrated understanding. The book also investigates where these approaches lead to and how they link design research more fully with other disciplines (e.g. psychology, cognition, sociology......, computer science, management). Above all, the book emphasizes the integrative nature of design research in terms of the methods, theories, and units of study—from the individual to the organizational level. Although this approach offers many advantages, it has inherently led to a situation in current...

  13. Experimental studies

    International Nuclear Information System (INIS)

    Cowser, K.E.; Stansbury, P.S.; Poston, J.W.; Deus, S.F.; Chen, W.L.; Roswell, R.L.; Goans, R.E.; Cantrell, J.H. Jr.


    Spectral fluence measurements in an adult phantom are reported. A NaI(Tl) probe was used in various locations within the phantom and pulse-height spectra were obtained for seven beam configurations and three generating potentials. Some typical spectra results are presented. A comparison of calculated dose to experimental measurements is presented

  14. Experimental guidelines

    International Nuclear Information System (INIS)


    The paper proposes a model experimental design to study the effects of pesticides on particular ecosystem. It takes maize as a model crop and an alternative crop while studying the adverse effects on untargeted arthropods, residues in the soil and other plants. 5 refs, 7 figs



    ALİKILIÇ, Dr. Özlem


    This article is based on the idea that user generated content is of fundamental importance in tourism and travel industry to understand the role of consumer generated messages. This paper also describes interpersonal influences mean for user generated content and also word of mouth (WOM) which reflect cost effective for tourism and travel industry but as well as the real crisis lead by the customer and discusses the new technological and ethical considerations facing tourism and travel industry

  16. Branded content infantil

    Directory of Open Access Journals (Sweden)



    Full Text Available Reseña del libro Bajo la influencia del branded content. Efectos de los contenidos de marca en niños y jóvenes. Review of the book Bajo la influencia del branded content. Efectos de los contenidos de marca en niños y jóvenes.

  17. Print advertising : Vivid content

    NARCIS (Netherlands)

    Fennis, B.M.; Das, E.H.H.J.; Fransen, M.L.

    The present research examines the effects of vivid ad content in two types of appeal in print ads as a function of individual differences in chronically experienced vividness of visual imagery. For informational ads for a functional product, vivid ad content strongly affected individuals high in

  18. Print advertising: vivid content

    NARCIS (Netherlands)

    Fennis, B.M.; Das, E.; Fransen, M.L.


    The present research examines the effects of vivid ad content in two types of appeal in print ads as a function of individual differences in chronically experienced vividness of visual imagery. For informational ads for a functional product, vivid ad content strongly affected individuals high in

  19. Qualitative Content Analysis


    Satu Elo; Maria Kääriäinen; Outi Kanste; Tarja Pölkki; Kati Utriainen; Helvi Kyngäs


    Qualitative content analysis is commonly used for analyzing qualitative data. However, few articles have examined the trustworthiness of its use in nursing science studies. The trustworthiness of qualitative content analysis is often presented by using terms such as credibility, dependability, conformability, transferability, and authenticity. This article focuses on trustworthiness based on a review of previous studie...

  20. Hydroponics: Content and Rationale (United States)

    Ernst, Jeremy V.; Busby, Joe R.


    Technology education has the means of becoming the catalyst for integrated content and curricula, especially in core academic areas, such as science and mathematics, where it has been found difficult to incorporate other subject matter. Technology is diverse enough in nature that it can be addressed by a variety of content areas, serving as a true…

  1. Rorschach contents in a Peruvian sample

    Directory of Open Access Journals (Sweden)

    Matilde Raez


    Full Text Available This study stressed the Rorschach-Content area in 237 Lima inhabitants. The Contents are an indicator that helps to understand the basic characteristics of personality (self-perception,interpersonal relations, cognitive mediation and ideation. This descriptive study used an accidental-probabilistic sample. The variables were age, gender, schooling, The descriptive statistic was used to analyze demographic contents and variables, and the non-parametric statistic (Kruskall-Wallis to compare data. The results stresses the absence of religious contents (R 1 and the importance of anatomic contents (An across the variables. The variable gender shows differences: men are interested in culture and show achievement motivation. Women are interested in home. With regarded lo schooling, the group including superior educated and complete secondary educated students shows solidarity signs, interest in socialization and ahigh cognitive level.

  2. List of Content

    Directory of Open Access Journals (Sweden)

    Editor IJRED


    Full Text Available CONTENTS OF ARTICLES page Tin (II Chloride Catalyzed Esterification of High FFA Jatropha Oil: Experimental and Kinetics Study DOI: 10.14710/ijred.3.2.75-81 75-81 Ratna Dewi Kusumaningtyas, Prima Astuti Handayani, Rochmadi Rochmadi, Suryo Purwono, Arief Budiman   Utilization of Iles-Iles and Sorghum Starch for Bioethanol Production DOI: 10.14710/ijred.3.2.83-89 83-89 Kusmiyati Kusmiyati, Agus Sulistiyono   Premixed Combustion of Kapok (ceiba pentandra seed oil on Perforated Burner DOI: 10.14710/ijred.3.2.91-97 91-97 I.K.G. Wirawan, I.N.G. Wardana,        Rudy Soenoko, Slamet Wahyudi   Castor Seed from Melkasa Agricultural Research Centre, East Showa, Ethiopia and it’s biodiesel performance in Four Stroke Diesel Engine DOI: 10.14710/ijred.3. 3.2.99-105 99-105 Tesfahun Tegegne Akanawa, Haimanot Gebrehiwot Moges, Ramesh Babu, Daniel Bisrat   Economic feasibility of large scale PV water pumping applications utilizing real field data for a case study in Jordan DOI: 10.14710/ijred.3.2.107-117 107-117 Ibrahim Odeh   Development of Briquette from Coir Dust and Rice Husk Blend: An Alternative Energy Source DOI: 10.14710/ijred.3.2.119-123 119-123 Md. Hamidul Islam, Md. Mosharraf Hossain,Md. Abdul Momin   Performance, Emissions and Combustion Characteristics of a Single Cylinder Diesel Engine Fuelled with Blends of Jatropha Methyl Ester and Diesel DOI: 10.14710/ijred.3.2.125-131 125-131 Debasish Padhee, Hifjur Raheman   The characteristic changes of betung bamboo (Dendrocalamus asper pretreated by fungal pretreatment DOI: 10.14710/ijred.3.2.133-143 133-143 Widya Fatriasari, Wasrin Syafii, Nyoman J Wistara, Khaswar Syamsu, Bambang Prasetya   Influence of the Determination Methods of K and C Parameters on the Ability of Weibull Distribution to Suitably Estimate Wind Potential and Electric Energy DOI: 10.14710/ijred.3.2.145-154 145-154 Ruben M. Mouangue, Myrin Y. Kazet, Alexis Kuitche, Jean-Marie Ndjaka    

  3. Social video content delivery

    CERN Document Server

    Wang, Zhi; Zhu, Wenwu


    This brief presents new architecture and strategies for distribution of social video content. A primary framework for socially-aware video delivery and a thorough overview of the possible approaches is provided. The book identifies the unique characteristics of socially-aware video access and social content propagation, revealing the design and integration of individual modules that are aimed at enhancing user experience in the social network context. The change in video content generation, propagation, and consumption for online social networks, has significantly challenged the traditional video delivery paradigm. Given the massive amount of user-generated content shared in online social networks, users are now engaged as active participants in the social ecosystem rather than as passive receivers of media content. This revolution is being driven further by the deep penetration of 3G/4G wireless networks and smart mobile devices that are seamlessly integrated with online social networking and media-sharing s...

  4. Experimental insertions

    International Nuclear Information System (INIS)

    Sandweiss, J.; Kycia, T.F.


    A discussion is given of the eight identical experimental insertions for the planned ISABELLE storage rings. Four sets of quadrupole doublets are used to match the β functions in the insertions to the values in the cells, and the total free space available at the crossing point is 40 meters. An asymmetric beam energy operation is planned, which will be useful in a number of experiments

  5. Animal experimentation


    Laz, Alak; Cholakova, Tanya Stefanova; Vrablova, Sofia; Arshad, Naverawaheed


    Animal experimentation is a crucial part of medical science. One of the ways to define it is any scientific experiment conducted for research purposes that cause any kind of pain or suffering to animals. Over the years, the new discovered drugs or treatments are first applied on animals to test their positive outcomes to be later used by humans. There is a debate about violating ethical considerations by exploiting animals for human benefits. However, different ethical theories have been made...

  6. Experimental and Theoretical Understanding of Neutron Capture on Uranium Isotopes

    Energy Technology Data Exchange (ETDEWEB)

    Ullmann, John Leonard [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)


    Neutron capture cross sections on uranium isotopes are important quantities needed to model nuclear explosion performance, nuclear reactor design, nuclear test diagnostics, and nuclear forensics. It has been difficult to calculate capture accurately, and factors of 2 or more be- tween calculation and measurements are not uncommon, although normalization to measurements of the average capture width and nuclear level density can improve the result. The calculations of capture for 233,235,237,239U are further complicated by the need to accurately include the fission channel.

  7. Animal experimentation. (United States)

    Kolar, Roman


    Millions of animals are used every year in often times extremely painful and distressing scientific procedures. Legislation of animal experimentation in modern societies is based on the supposition that this is ethically acceptable when certain more or less defined formal (e.g. logistical, technical) demands and ethical principles are met. The main parameters in this context correspond to the "3Rs" concept as defined by Russel and Burch in 1959, i.e. that all efforts to replace, reduce and refine experiments must be undertaken. The licensing of animal experiments normally requires an ethical evaluation process, often times undertaken by ethics committees. The serious problems in putting this idea into practice include inter alia unclear conditions and standards for ethical decisions, insufficient management of experiments undertaken for specific (e.g. regulatory) purposes, and conflicts of interest of ethics committees' members. There is an ongoing societal debate about ethical issues of animal use in science. Existing EU legislation on animal experimentation for cosmetics testing is an example of both the public will for setting clear limits to animal experiments and the need to further critically examine other fields and aspects of animal experimentation.

  8. Understanding and control of optical performance from ceramic materials

    International Nuclear Information System (INIS)

    Barbour, J.C.; Knapp, J.A.; Potter, B.G.; Jennison, D.R.; Verdozzi, C.A.; Follstaedt, D.M.; Bendale, R.D.; Simmons, J.H.


    This report summarizes a two-year Laboratory-Directed Research and Development (LDRD) program to gain understanding and control of the important parameters which govern the optical performance of rare-earth (RE) doped ceramics. This LDRD developed the capability to determine stable atomic arrangements in RE doped alumina using local density functional theory, and to model the luminescence from RE-doped alumina using molecular dynamic simulations combined with crystal-field calculations. Local structural features for different phases of alumina were examined experimentally by comparing their photoluminescence spectra and the atomic arrangement of the amorphous phase was determined to be similar to that of the gamma phase. The luminescence lifetimes were correlated to these differences in the local structure. The design of both high and low-phonon energy host materials was demonstrated through the growth of Er-doped aluminum oxide and lanthanum oxide. Multicomponent structures of rare-earth doped telluride glass in an alumina and silica matrix were also prepared. Finally, the optical performance of Er-doped alumina was determined as a function of hydrogen content in the host matrix. This LDRD is the groundwork for future experimentation to understand the effects of ionizing radiation on the optical properties of RE-doped ceramic materials used in space and other radiation environments

  9. Understanding Puberty (For Parents) (United States)

    [Skip to Content] for Parents Parents site Sitio para padres General Health Growth & Development Infections Diseases & Conditions Pregnancy & Baby Nutrition & Fitness Emotions & Behavior School & Family ...

  10. Understanding Dyslexia (For Parents) (United States)

    [Skip to Content] for Parents Parents site Sitio para padres General Health Growth & Development Infections Diseases & Conditions Pregnancy & Baby Nutrition & Fitness Emotions & Behavior School & Family ...

  11. Understanding computer and information technology

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Yun Cheol; Han, Tack Don; Im, Sun Beom


    This book consists of four parts. The first part describes IT technology and information community understanding of computer system, constitution of software system and information system and application of software. The second part is about computer network, information and communication, application and internet service. The third part contains application and multi media, application of mobile computer, ubiquitous computing and ubiquitous environment and computer and digital life. The last part explains information security and ethics of information-oriented society, information industry and IT venture, digital contents technology and industry and the future and development of information-oriented society.

  12. Experimental Volcanology: 2010 and 2020 (United States)

    Dingwell, D. B.


    The advent of an experimental approach to volcanology has its roots in decades-old laboratory based approaches to characterising the properties of magmas and analog materials, together with the attempts at simulating volcanic processes in the lab. A little over ten years ago many new thrusts of experimental advance led to a new dawn for experimental science applied to volcanic eruptions. Along with that, new expectations, new goals and new strategies emerged about ten years ago. Ten years later, in 2010, many fruits have been born of this labour, and new frontiers are being unfolded as we meet here. Here are some of the youngest captivating themes being explored in experimental programs today: 1) interfacing volcanic monitoring systems to experimentally generated eruptions. 2) elucidating the physicochemical behavior of experimentally generated volcanic ash as an agent in the earth system. 3) blending experimental rock deformation and magmatology studies to understand the strength and stability of volcanic materials and volcanic structures 4) exploiting the kinematics of experimentally-generated versus natural volcanic products to understand flow style and strain history. The past ten years of experimental developments in volcanology have prepared us for great advances in the future, most of which were not perceived as likely avenues of investigation as little as ten years ago! The situation is likely to repeat itself in 2020.

  13. Encryption for digital content

    CERN Document Server

    Kiayias, Aggelos


    Encryption for Digital Content is an area in cryptography that is widely used in commercial productions (e.g., Blu-Ray and HD-DVDs). This book provides a comprehensive mathematical treatment of combinatorial encryption techniques used in digital content distribution systems and related attack models. A complete description of broadcast encryption with various revocation and tracing functionalities is included. ""Encryption for Digital Content"" introduces the subset cover framework (currently used in AACS, Blu-Ray and HD-DVDs,) and tracking/revocation mechanisms in various attack models. Pirat

  14. Understanding the Precipitated Calcium Carbonate (PCC ...

    African Journals Online (AJOL)

    The particle morphology and texture as well as the chemical content were sufficiently authenticated using X-ray diffraction (XRD), Fourier transforminfrared spectroscopy (FTIR), scanning electron microscope (SEM) and X-ray fluorescence (XRF). Experimental data show that lower concentration (<1.0 M) favoured the ...

  15. Learning Content Management Systems

    Directory of Open Access Journals (Sweden)



    Full Text Available The paper explains the evolution of e-Learning and related concepts and tools and its connection with other concepts such as Knowledge Management, Human Resources Management, Enterprise Resource Planning, and Information Technology. The paper also distinguished Learning Content Management Systems from Learning Management Systems and Content Management Systems used for general web-based content. The newest Learning Content Management System, very expensive and yet very little implemented is one of the best tools that helps us to cope with the realities of the 21st Century in what learning concerns. The debates over how beneficial one or another system is for an organization, can be driven by costs involved, efficiency envisaged, and availability of the product on the market.

  16. Nutrient Content Claims (United States)

    ... 8, 2014 Articles from Diabetes Forecast® magazine: wcie-nutrition, . In this section Food What Can I Eat Food Tips Eating Out Quick Meal Ideas Cutting Back on Sodium Nutrient Content Claims Snacks Taking ...

  17. The Experimental Design Ability Test (EDAT) (United States)

    Sirum, Karen; Humburg, Jennifer


    Higher education goals include helping students develop evidence based reasoning skills; therefore, scientific thinking skills such as those required to understand the design of a basic experiment are important. The Experimental Design Ability Test (EDAT) measures students' understanding of the criteria for good experimental design through their…


    Directory of Open Access Journals (Sweden)

    V. Kukharenko


    Full Text Available Content curated - a new activity (started in 2008 qualified network users with process large amounts of information to represent her social network users. To prepare content curators developed 7 weeks distance course, which examines the functions, methods and tools curator. Courses showed a significant relationship success learning on the availability of advanced personal learning environment and the ability to process and analyze information.

  19. Robust, Reliable Low Emission Gas Turbine Combustion of High Hydrogen Content Fuels

    Energy Technology Data Exchange (ETDEWEB)

    Wooldridge, Margaret Stacy [Univ. of Michigan, Ann Arbor, MI (United States); Im, Hong Geum [Univ. of Michigan, Ann Arbor, MI (United States)


    The effects of high hydrogen content fuels were studied using experimental, computational and theoretical approaches to understand the effects of mixture and state conditions on the ignition behavior of the fuels. A rapid compression facility (RCF) was used to measure the ignition delay time of hydrogen and carbon monoxide mixtures. The data were combined with results of previous studies to develop ignition regime criteria. Analytical theory and direct numerical simulation were used to validate and interpret the RCF ignition data. Based on the integrated information the ignition regime criteria were extended to non-dimensional metrics which enable application of the results to practical gas turbine combustion systems.

  20. Metaphor, skepticism, understanding Metaphor, skepticism, understanding

    Directory of Open Access Journals (Sweden)

    Helena Martins


    Full Text Available

    This paper examines the idea that metaphor is a basic cognitive tool from a Wittgensteinian point of view. One specific aspect of Wittgenstein’s legacy is explored, namely his account of verbal understanding. Two interconnected and notoriously difficult features of this account are highlighted and discussed: the idea that linguistic understanding is not an event or a process, but an “abiding condition” (Philosophical Investigations, §143-84; and the idea that neither the meaning of a linguistic expression nor our understanding of it can ever go beyond our capacity of explaining it (Philosophical Investigations, §75. This perspective is shown to be particularly apt in reflecting upon the virtues of metaphor as a means of understanding, especially because it allows for the avoidance of both essentialist and skeptical accounts.

    This paper examines the idea that metaphor is a basic cognitive tool from a Wittgensteinian point of view. One specific aspect of Wittgenstein’s legacy is explored, namely his account of verbal understanding. Two interconnected and notoriously difficult features of this account are highlighted and discussed: the idea that linguistic understanding is not an event or a process, but an “abiding condition” (Philosophical Investigations, §143-84; and the idea that neither the meaning of a linguistic expression nor our understanding of it can ever go beyond our capacity of explaining it (Philosophical Investigations, §75. This perspective is shown to be particularly apt in reflecting upon the virtues of metaphor as a means of understanding, especially because it allows for the avoidance of both essentialist and skeptical accounts

  1. Adapting Content Subject Tasks for Bilingual Teaching (United States)

    Halbach, Ana


    Teaching content through a foreign language presents students with the double challenge of having to understand new concepts and of doing so through a foreign language. To be successful in meeting this challenge teachers have to adapt their teaching style and the tasks they work on with their students. Often, however, they do not know how to do…

  2. Princess Picture Books: Content and Messages (United States)

    Dale, Lourdes P.; Higgins, Brittany E.; Pinkerton, Nick; Couto, Michelle; Mansolillo, Victoria; Weisinger, Nica; Flores, Marci


    Because many girls develop their understanding of what it means to be a girl from books about princesses, the researchers coded the messages and content in 58 princess books (picture, fairy tales, and fractured fairy tales). Results indicate that gender stereotypes are present in the books--the princesses were more likely to be nurturing, in…

  3. Understanding Identity and Organizations

    DEFF Research Database (Denmark)

    Christensen, Lars Thøger


    The article reviews the book "Understanding Identity and Organizations," by Kate Kenny, Andrea Whitle, and Hugh Wilmott.......The article reviews the book "Understanding Identity and Organizations," by Kate Kenny, Andrea Whitle, and Hugh Wilmott....

  4. Understanding Hereditary Angioedema (United States)

    ... Allergy Library ▸ Understanding Hereditary Angioedema Share | Understanding Hereditary Angioedema This article has been reviewed by Thanai Pongdee, MD, FAAAAI Hereditary Angioedema (HAE) is a rare genetic condition. People with ...

  5. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available ... Prognosis Questions to Ask about Your Diagnosis Research Understanding Cancer Prognosis Oncologist Anthony L. Back, M.D., ... find our information on Coping With Cancer helpful. Understanding Statistics About Survival Doctors estimate prognosis by using ...

  6. Understanding in mathematics

    CERN Document Server

    Sierpinska, Anna


    The concept of understanding in mathematics with regard to mathematics education is considered in this volume, the main problem for mathematics teachers being how to facilitate their students'' understanding of the mathematics being taught.

  7. Understanding Food Labels (United States)

    ... Healthy eating for girls Understanding food labels Understanding food labels There is lots of info on food ... need to avoid because of food allergies. Other food label terms top In addition to the Nutrition ...

  8. Optimizing cementious content in concrete mixtures for required performance. (United States)


    "This research investigated the effects of changing the cementitious content required at a given water-to-cement ratio (w/c) on workability, strength, and durability of a concrete mixture. : An experimental program was conducted in which 64 concrete ...

  9. Valuation of Understanding

    DEFF Research Database (Denmark)

    Wiberg, Merete

    An important aim for the teacher in Higher Education is that students, in order to learn, achieve understanding in terms of being able to handle knowledge in a certain way. In this paper focus will be on understanding as a phenomenon which is permeated with values of what good understanding might...... be. Understanding is to be discussed as a phenomenon which in its definition is relative to the paradigm of educational thinking in which it is embedded. Paradigms of valuation of understanding in higher education will be viewed from two perspectives: An anglosaxon curriculum studies tradition...

  10. Memorandum of Understanding.

    Energy Technology Data Exchange (ETDEWEB)

    Siple, Bud H. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)


    A Memorandum of Understanding establishes a clear understanding of how an agreement is going to be implemented. The Memorandum of Understanding allows all involved to specifically understand that they are agreeing to the same thing and the terms are clearly identified. It also includes the clear distinction of functions and the level of involvement of the agencies involved. Specifically, a Memorandum of Understanding gives a chance to all of those involved in the agreement to see on paper as to what they all have agreed to.

  11. Experimental Seminar on Nuclear Energy for Teachers

    Energy Technology Data Exchange (ETDEWEB)



    `Experimental Seminar on Nuclear Energy for Teachers` was conducted and sponsored by the Science and Technology Agency. And in order to understand nuclear energy properly through lectures and experiments with good results inclass, the seminar carried out for teachers of high schools and junior high schools by the Nuclear Technology and Education Center (NuTEC), Japan Atomic Energy Research Institute in 1990 FY to 1997 FY. In this report, details of the seminars in the above period are described and No.1 to 17 of Communication Letters of Experimental Seminar on Nuclear Energy` started at 1992 FY are described also. These letters were prepared for attendant follow-up program. And programs of recent seminars, future`s seminars, impressions and comments from attendants, reports from actual classes and others are described in these letters and they are very useful for educational classes on nuclear energy by other teachers. Therefore contents of the letters are listed and easy to refer. A part of this educational task was transferred to the Radiation Application Development Association in 1997 FY and other parts were transferred in 1998 FY. (author)

  12. Tourist-created Content

    DEFF Research Database (Denmark)

    Munar, Ana Maria


    study of social media sites and destination brands, relying on qualitative research methods, content analysis and field research. Findings – Tourists are largely contributing to destination image formation, while avoiding the use of the formal elements of the brands. The most popular strategies used......Purpose – The purpose of this paper is to analyze the relationship between tourists' user-generated content on the web and destination branding, as well as to discuss the online strategies used by destination management organizations. Design/methodology/approach – The research adopts an exploratory...... by destination management organizations exhibit some crucial weaknesses. However, a strategy based on analytics brings new opportunities for destination branding. Originality/value – The study provides an innovative analysis of tourist-created content and its impact on destination branding and presents...

  13. When Do Children Understand "Opposite"? (United States)

    Phillips, Catherine I; Pexman, Penny M


    The aims of the present research were to determine (a) the age at which children with typical development understand the concept of opposite, (b) whether this is related to other cognitive abilities or experiences, and (c) whether there is early implicit understanding of the concept. Children (N = 204) between 3 and 5 years of age were randomly assigned to 1 of 3 experimental conditions in a novel opposite task. Children's language and working memory skills were assessed, and parents provided information about children's access to learning materials about opposites. In the opposite task, 4- and 5-year-olds, but not 3-year-olds, demonstrated acquisition of the concept of opposite. Children demonstrated this understanding only when asked for the "opposite" one, suggesting that antonymy was not made salient by stimulus properties alone. Children's accuracy was not significantly related to their language or working memory skills, to their child care experience, or to whether parents reported having books or games about opposites or playing opposite word games with children. Eye gaze analyses provided no evidence for early implicit understanding of the concept of opposite. Children with typical development have a concept of opposite by 4 years of age.

  14. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available Skip to content Español 1-800-4-CANCER Live Chat Publications Dictionary Menu Contact Dictionary Search About Cancer Causes and Prevention Risk Factors Genetics Cancer Prevention Overview Research Cancer ...

  15. Content addressable memories in scientific instruments

    International Nuclear Information System (INIS)

    Lotto, I. de; Golinelli, S.


    The content-addressable-memory feature of a new system designed in these laboratories for non-destructive testing of nuclear reactor pressure vessels based on acoustic emission analysis is presented. The content addressable memory is divided into two parts: the first selects the most frequent events among incoming ones (FES: Frequent Event Selection memory), the second stores the frequent events singled out (FEM: Frequent Event Memory). The statistical behaviour of FES is analyzed, and experimental results are compared with theoretical ones; the model presented proved to be a useful tool in dimensioning the instrument store capacity. (Auth.)

  16. Water and deuterium content of chondrites

    International Nuclear Information System (INIS)

    Robert, Francois


    The main objective of this research thesis which deals with meteorite study, is to develop an experimental technique to measure the hydrogen isotopic rate in the case of very low quantities of hydrogen, notably in samples in which water content is hundred or thousand times less than in reported experiments, in order to study mechanisms of alteration of chondrites. The author reports an attempt to reconcile obtained results for isotopic rates as well as for water contents with those of the main existing models of chondrite formation. He proposes a detailed description of isotopic exchange mechanisms at low temperature, and shows that this mechanism is not in disagreement with literature published on chondrites

  17. Experimental music for experimental physics

    CERN Multimedia

    Rosaria Marraffino


    Using the sonification technique, physicist and composer Domenico Vicinanza paid homage to CERN at its 60th anniversary ceremony. After months of hard work, he turned the CERN Convention and LHC data into music.   Click here to download the full score of the "LHChamber music". Every birthday deserves gifts and CERN’s 60th anniversary was no exception. Two gifts were very special, thanks to the hard work of Domenico Vicinanza, a physicist and composer. He created two experimental pieces by applying the sonification technique to the CERN Convention and to data recorded by the four LHC detectors during Run 1. “This technique allows us to ‘hear’ data using an algorithm that translates numbers or letters into notes. It keeps the same information enclosed in a graph or a document, but has a more aesthetic exposition,” explains Domenico Vicinanza. “The result is meant to be a metaphor for scientific cooperation, in which d...

  18. Quantification of Cannabinoid Content in Cannabis (United States)

    Tian, Y.; Zhang, F.; Jia, K.; Wen, M.; Yuan, Ch.


    Cannabis is an economically important plant that is used in many fields, in addition to being the most commonly consumed illicit drug worldwide. Monitoring the spatial distribution of cannabis cultivation and judging whether it is drug- or fiber-type cannabis is critical for governments and international communities to understand the scale of the illegal drug trade. The aim of this study was to investigate whether the cannabinoids content in cannabis could be spectrally quantified using a spectrometer and to identify the optimal wavebands for quantifying the cannabinoid content. Spectral reflectance data of dried cannabis leaf samples and the cannabis canopy were measured in the laboratory and in the field, respectively. Correlation analysis and the stepwise multivariate regression method were used to select the optimal wavebands for cannabinoid content quantification based on the laboratory-measured spectral data. The results indicated that the delta-9-tetrahydrocannabinol (THC) content in cannabis leaves could be quantified using laboratory-measured spectral reflectance data and that the 695 nm band is the optimal band for THC content quantification. This study provides prerequisite information for designing spectral equipment to enable immediate quantification of THC content in cannabis and to discriminate drug- from fiber-type cannabis based on THC content quantification in the field.

  19. Factors stimulating content marketing

    Directory of Open Access Journals (Sweden)

    Naser Azad


    Full Text Available This paper presents an empirical investigation to determine factors influencing on content marketing in banking industry. The study designs a questionnaire consists of 40 questions in Likert scale and distributes it among 550 randomly selected regular customers of Bank Mellat in city of Tehran, Iran and 400 properly filled questionnaires are collected. Cronbach alphas for all components of the survey are well above desirable level. Using principle component analysis with Varimax rotation, the study has determined six factors influencing the most on content marketing including organization, details, having new ideas, quality, sensitivity and power while the last component contains only two subcomponents and is removed from the study.

  20. Lycopene Content of Selected Tomato Based Products, Fruits and ...

    African Journals Online (AJOL)

    The Lycopene content of selected tomato based products, fruits and vegetables, commonly consumed in South Western Nigeria were determined using theoretical and experimental method. The lycopene content in tomato pastes ranged from 50.97±1.08 mg/kg in vitali tomato paste to 68.12±1.44 mg/kg in Gino tomato paste ...

  1. Effect of alloy content on microstructure and microchemistry of ...

    Indian Academy of Sciences (India)

    This paper presents the results of an experimental study on the microstructural evolution in 9Cr reduced activation ferritic/martensitic steels during short term thermal exposures. Since the microstructure is strongly influenced by the alloying additions, mainly W, Ta and C contents, the effect of varying W and Ta contents on ...

  2. Inter-relationships between hydrogen and carbon contents of ...

    African Journals Online (AJOL)

    Empirical relationships between hydrogen and carbon contents and the calorific values of rice husks, cotton see-ds, jatropha seeds, palm kernel shells and cashew shells were investigated. The experimental data indicated higher correlation coefficient between calorific values and hydrogen content than between calorific ...

  3. Density content of nuclear symmetry energy from nuclear observables

    Indian Academy of Sciences (India)

    The density content of nuclear symmetry energy remains poorly constrained. Our recent results for the density content of the nuclear symmetry energy, around the saturation density, extracted using experimental data for accurately known nuclear masses, giant resonances and neutron-skin thickness in heavy nuclei are.

  4. Arsenic Content in American Wine. (United States)

    Wilson, Denise


    Recent studies that have investigated arsenic content in juice, rice, milk, broth (beef and chicken), and other foods have stimulated an interest in understanding how prevalent arsenic contamination is in the U.S. food and beverage supply. The study described here focused on quantifying arsenic levels in wine. A total of 65 representative wines from the top four wine-producing states in the U.S. were analyzed for arsenic content. All samples contained arsenic levels that exceeded the U.S. Environmental Protection Agency (U.S. EPA) exposure limit for drinking water of 10 parts per billion (ppb) and all samples contained inorganic arsenic. The average arsenic detected among all samples studied was 23.3 ppb. Lead, a common co-contaminant to arsenic, was detected in 58% of samples tested, but only 5% exceeded the U.S. EPA exposure limit for drinking water of 15 ppb. Arsenic levels in American wines exceeded those found in other studies involving water, bottled water, apple juice, apple juice blend, milk, rice syrup, and other beverages. When taken in the context of consumption patterns in the U.S., the pervasive presence of arsenic in wine can pose a potential health risk to regular adult wine drinkers.

  5. Understanding quantum physics

    International Nuclear Information System (INIS)

    Spillner, Vera


    This thesis presents a bundle definition for 'scientific understanding' through which the empirically equivalent interpretations of quantum mechanics can be evaluated with respect to the understanding they generate. The definition of understanding is based on a sufficient and necessary criterion, as well as a bundle of conditions - where a theory can be called most understandable whenever it fulfills the highest number of bundle criteria. Thereby the definition of understanding is based on the one hand on the objective number of criteria a theory fulfills, as well as, on the other hand, on the individual's preference of bundle criteria. Applying the definition onto three interpretations of quantum mechanics, the interpretation of David Bohm appears as most understandable, followed by the interpretation of Tim Maudlin and the Kopenhagen interpretation. These three interpretations are discussed in length in my thesis. (orig.)

  6. Caution, contention, and consolidation. (United States)

    Dorr, Robert F


    The Washington Watch column provides an overview of NASA's cautious approach to the launch of Space Shuttle Discovery STS-114, contention between the Air Force and administration about production of the F/A-22 Raptor aircraft, and consolidation among U.S. airline companies.

  7. Content Area Instructional Strategies (United States)

    Montgomery, Joel R.


    The aim of this working paper is to identify research-supported strategies for content that can be integrated effectively to promote the development of biliterate academic literacy by English language learners (ELLs) in middle-school bilingual classrooms. The paper provides a research-based summary of relevant learning needs of adolescent…

  8. Loser Generated Content

    DEFF Research Database (Denmark)

    Petersen, Søren Mørk


    , is that the Internet functions as a double–edged sword; the infrastructure does foster democracy, participation, joy, creativity and sometimes creates zones of piracy. But, at the same time, it has become evident how this same infrastructure also enables companies easily to piggyback on user generated content...

  9. Video Content Foraging

    NARCIS (Netherlands)

    van Houten, Ynze; Schuurman, Jan Gerrit; Verhagen, Pleunes Willem; Enser, Peter; Kompatsiaris, Yiannis; O’Connor, Noel E.; Smeaton, Alan F.; Smeulders, Arnold W.M.


    With information systems, the real design problem is not increased access to information, but greater efficiency in finding useful information. In our approach to video content browsing, we try to match the browsing environment with human information processing structures by applying ideas from

  10. Digital Content Licensing

    DEFF Research Database (Denmark)

    Schwemer, Sebastian Felix

    -legislative) initiatives, which support the facilitation of multi-territorial licensing and cross-border access to content. It investigates the regulation of two online markets, which have recently been subject to scrutiny by the EU institutions: the audiovisual and the music sector, both addressed by ex ante sector...

  11. LCS Content Document Application (United States)

    Hochstadt, Jake


    My project at KSC during my spring 2011 internship was to develop a Ruby on Rails application to manage Content Documents..A Content Document is a collection of documents and information that describes what software is installed on a Launch Control System Computer. It's important for us to make sure the tools we use everyday are secure, up-to-date, and properly licensed. Previously, keeping track of the information was done by Excel and Word files between different personnel. The goal of the new application is to be able to manage and access the Content Documents through a single database backed web application. Our LCS team will benefit greatly with this app. Admin's will be able to login securely to keep track and update the software installed on each computer in a timely manner. We also included exportability such as attaching additional documents that can be downloaded from the web application. The finished application will ease the process of managing Content Documents while streamlining the procedure. Ruby on Rails is a very powerful programming language and I am grateful to have the opportunity to build this application.

  12. The impact of content marketing on attitudes and purchase intentions of online shoppers : the case videos & tutorials and user-generated content


    Milhinhos, Patrícia Raquel Vasques


    This thesis was written as part of a Double-Degree Masters program in Management, with focus in Marketing. Aligned with the nature of the degree, this study aims to be a useful tool for managers and marketers, which conduct business online. This thesis is a study of Content Marketing in the content of online commercial product pages. Its aim is to understand how to use content marketing to drive conversion, by understanding consumer attitudes and purchase intention towards content. A in...

  13. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available ... our information on Coping With Cancer helpful. Understanding Statistics About Survival Doctors estimate prognosis by using statistics that researchers have collected over many years about ...

  14. Coalbed gas content simulation test and application

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, S. [New Star Petroleum Company, Zhengzhou (China). North China Petroleum Bureau


    With a high-pressure canister and accurate thermoregulation system of IS-100 isotherm instrument and an electronic flow meter, a coalbed gas content simulation method is established. A control program is combined with it to control data acquisition. The method simulates the whole process of gas content measurement from coring to the completion of desorption. It enables the understanding of gas desorption regularities, and for obtaining the volume of gas loss at any one time. The study would be useful for comparing the various approaches of calculating gas loss volume. 3 refs., 5 figs.

  15. Practical guide to content delivery networks

    CERN Document Server

    Held, Gilbert


    With a practical and organized approach to learning and implementation, A Practical Guide to Content Delivery Networks presents a step-by-step process for building a highly available and highly scalable content delivery network (CDN). CDN refers to the infrastructure behind any service that provides utility or access to data to an end user. This book offers terminology, tactics, potential problems to avoid, and individual layers of design, providing clear understanding of the framework for CDNs using a structural and visual approach. The text emphasizes a best-of-breed strategy, allowing a tec

  16. Understanding cancer onset

    DEFF Research Database (Denmark)

    Veldhuis, Djuke


    Researchers in Malaysia analysed the genomes of people with a rare genetic disorder to better understand people’s predisposition to cancer across generations.......Researchers in Malaysia analysed the genomes of people with a rare genetic disorder to better understand people’s predisposition to cancer across generations....

  17. Understanding Menstrual Migraine. (United States)

    Calhoun, Anne H


    Menstrual-related migraine is very prevalent, very disabling, yet very easy to manage given a good understanding of its cause. This article is intended to help with that understanding and to enable headache specialists to prescribe or create effective hormonal preventives of menstrual-related migraine. © 2018 American Headache Society.

  18. Understanding the visual resource (United States)

    Floyd L. Newby


    Understanding our visual resources involves a complex interweaving of motivation and cognitive recesses; but, more important, it requires that we understand and can identify those characteristics of a landscape that influence the image formation process. From research conducted in Florida, three major variables were identified that appear to have significant effect...

  19. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available ... Questions to Ask about Your Diagnosis Research Understanding Cancer Prognosis Oncologist Anthony L. Back, M.D., a ... for provider care teams (PDF-210KB). Understanding Your Cancer Prognosis Video View this video on YouTube. Three ...

  20. Content Maps: A Teaching and Assessment Tool for Content Knowledge (United States)

    Ward, Phillip; Lehwald, Harry; Lee, Yun Soo


    Developing content knowledge in teachers presents a constant challenge for teacher educators. This article introduces a teaching and assessment tool called a "content map," which allows teacher educators, teachers, and coaches to conceptualize the scope, sequence, and relational characteristics of the content being taught. Content maps…

  1. Low-Power, Lightweight Cloud Water Content Sensor, Phase II (United States)

    National Aeronautics and Space Administration — The measurement of cloud water content is of great importance in understanding the formation of clouds, their structure, and their radiative properties which in turn...

  2. The effects of volcanic eruptions on simulated ocean heat content and thermal expansion (United States)

    Gleckler, P.; Achutarao, K.; Barnett, T.; Gregory, J.; Pierce, D.; Santer, B.; Taylor, K.; Wigley, T.


    We examine the ocean heat content in a recent suite of coupled ocean-atmosphere model simulations of the 20th Century. Our results suggest that 20th Century increases in ocean heat content and sea-level (via thermal expansion) were substantially reduced by the 1883 eruption of Krakatoa. The volcanically-induced cooling of the ocean surface is subducted into deeper ocean layers, where it persists for decades. Temporary reductions in ocean heat content associated with the comparable eruptions of El Chichon (1982) and Pinatubo (1991) were much shorter lived because they occurred relative to a non-stationary background of large, anthropogenically-forced ocean warming. To understand the response of these simulations to volcanic loadings, we focus on multiple realizations of the 20th Century experiment with three models (NCAR CCSM3, GFDL 2.0, and GISS HYCOM). By comparing these runs to control simulations of each model, we track the three dimensional oceanic response to Krakatoa using S/N analysis. Inter-model differences in the oceanic thermal response to Krakatoa are large and arise from differences in external forcing, model physics, and experimental design. Our results suggest that inclusion of the effects of Krakatoa (and perhaps even earlier eruptions) is important for reliable simulation of 20th century ocean heat uptake and thermal expansion. Systematic experimentation will be required to quantify the relative importance of these factors.

  3. Determination of Fat Content (United States)

    Carpenter, Charles

    The term "lipid" refers to a group of compounds that are sparingly soluble in water, but show variable solubility in a number of organic solvents (e.g., ethyl ether, petroleum ether, acetone, ethanol, methanol, benzene). The lipid content of a food determined by extraction with one solvent may be quite different from the lipid content as determined with another solvent of different polarity. Fat content is determined often by solvent extraction methods (e.g., Soxhlet, Goldfish, Mojonnier), but it also can be determined by nonsolvent wet extraction methods (e.g., Babcock, Gerber), and by instrumental methods that rely on the physical and chemical properties of lipids (e.g., infrared, density, X-ray absorption). The method of choice depends on a variety of factors, including the nature of the sample (e.g., dry versus moist), the purpose of the analysis (e.g., official nutrition labeling or rapid quality control), and instrumentation available (e.g., Babcock uses simple glassware and equipment; infrared requires an expensive instrument).

  4. Content Documents Management (United States)

    Muniz, R.; Hochstadt, J.; Boelke J.; Dalton, A.


    The Content Documents are created and managed under the System Software group with. Launch Control System (LCS) project. The System Software product group is lead by NASA Engineering Control and Data Systems branch (NEC3) at Kennedy Space Center. The team is working on creating Operating System Images (OSI) for different platforms (i.e. AIX, Linux, Solaris and Windows). Before the OSI can be created, the team must create a Content Document which provides the information of a workstation or server, with the list of all the software that is to be installed on it and also the set where the hardware belongs. This can be for example in the LDS, the ADS or the FR-l. The objective of this project is to create a User Interface Web application that can manage the information of the Content Documents, with all the correct validations and filters for administrator purposes. For this project we used one of the most excellent tools in agile development applications called Ruby on Rails. This tool helps pragmatic programmers develop Web applications with Rails framework and Ruby programming language. It is very amazing to see how a student can learn about OOP features with the Ruby language, manage the user interface with HTML and CSS, create associations and queries with gems, manage databases and run a server with MYSQL, run shell commands with command prompt and create Web frameworks with Rails. All of this in a real world project and in just fifteen weeks!


    Directory of Open Access Journals (Sweden)

    Tengku Nor Rizan Tengku Mohamad Maasum


    Full Text Available Advocates of the content-based approach believed that a language can be learnt effectively when it is the medium of instruction rather than just a subject. Integrating English and content as part of instruction has become one of the cornerstones of second language pedagogy. Researchers claimed that there are many benefits of integrating English and content instruction. Among the benefits are the increase in students’ interest with content themes, meaningful input and understanding. In 2003, the Malaysian Ministry of Education introduced the teaching and learning of science and mathematics in English for Year One, Form One and Lower Six Form in all government public schools. This paper describes the challenges faced by teachers when they are required to teach content subjects such as science and mathematics in English. The focus of the paper is on the teachers’ pedagogical skills and content knowldge which comprises subject matter content, pedagogical approach, classroom management, use of resources, assessment, preparation of teaching materials, managing students, teachers’ compensatory communication strategies, use of first language and teachers’ perspectives of teaching content subjects in English. Data were obtained from a self-report questionnaire administered to 495 secondary school teachers in West Malaysia. Results from the study provide implications for school administrators in making decisions in assignment of capable teachers to teach the various levels of classes. Suggestions for teacher self-development and life-long learning efforts are also provided.

  6. The Role of Content in Inquiry-Based Elementary Science Lessons: An Analysis of Teacher Beliefs and Enactment (United States)

    Furtak, Erin Marie; Alonzo, Alicia C.


    The Trends in International Mathematics and Science Study (TIMSS) Video Study explored instructional practices in the United States (US) in comparison with other countries that ranked higher on the 1999 TIMSS assessment, and revealed that 8th grade science teachers in the US emphasize activities over content during lessons (Roth et al. 2006). This study applies the content framework from the TIMSS Video Study to a sample of 28 3rd grade teachers enacting an inquiry-based unit on floating and sinking, and seeks a deeper understanding of teachers’ practices through analysis of interviews with those teachers. Transcripts of observed lessons were coded according to the TIMSS framework for types of content, and transcripts of teacher interviews were coded to capture the ways in which teachers described their role in and purposes for teaching science, particularly with respect to the floating and sinking unit. Results indicate that teachers focused more on canonical, procedural and experimental knowledge during lessons than on real-world connections and the nature of science; however, none of the types of content received major emphasis in a majority of the classrooms in the sample. During interviews, teachers described their practice in ways that prioritized helping students to like science over specific content outcomes. The study suggests that elementary school teachers’ emphasis on doing and feeling during inquiry-based lessons may interfere with teaching of content.

  7. Government Influence on Print Media Content in Pakistan: Pakistani ...

    African Journals Online (AJOL)

    However, it is equally important to understand the influences that shape content. This study investigates the government's influence on print media content in Pakistan due to its advertising and economic power. The results of the study show that journalists are of the view that the government has a very strong influence on ...

  8. Building Blocks to Colorado's Content Standards: Mathematics, Reading and Writing. (United States)

    Allen-Young, Darcy; Amundson, Jane L.; Bowers, Lori Goodwin; Koehn, Jo; Triolo-Moloney, Sharon; Vendegna, Nan; Peterson, Sandra

    The Building Blocks to Colorado's Content Standards were developed to connect early childhood education to the K-12 content standards, to advocate for appropriate teaching strategies for preschool children, and to support awareness and understanding of early childhood foundational skills among parents and teachers. Five sets of building blocks are…

  9. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available ... content Español 1-800-4-CANCER Live Chat Publications Dictionary Menu Contact Dictionary Search About Cancer Causes ... and Young Adults with Cancer Reports, Research, and Literature Cancers by Body Location/System Childhood Cancers Late ...

  10. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available Skip to content Español 1-800-4-CANCER Live Chat Publications Dictionary Menu Contact Dictionary Search About ... to tell her how long she has to live. For Doctors, a Patient-Centered Approach View this ...

  11. Understanding Grief and Loss (United States)

    ... to Content Conquer Cancer Foundation ASCO Journals Donate eNews Signup f on Facebook t on Twitter q on YouTube g on Google Menu Home Types of Cancer Navigating Cancer Care Coping With Cancer Managing Emotions Self-Image and Cancer ...

  12. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available ... to content Español 1-800-4-CANCER Live Chat Publications Dictionary Menu Contact Dictionary Search About Cancer ... GovDelivery RSS CONTACT INFORMATION Contact Us LiveHelp Online Chat MORE INFORMATION About This Website en ...

  13. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available Skip to content Español 1-800-4-CANCER Live Chat Publications Dictionary Menu Contact Dictionary Search About Cancer Causes and Prevention Risk Factors ... MORE INFORMATION About This Website en español Multimedia Publications Site Map Digital Standards for NCI ...

  14. Math: Basic Skills Content Standards (United States)

    CASAS - Comprehensive Adult Student Assessment Systems (NJ1), 2008


    This document presents content standards tables for math. [CASAS content standards tables are designed for educators at national, state and local levels to inform the alignment of content standards, instruction and assessment. The Content Standards along with the CASAS Competencies form the basis of the CASAS integrated assessment and curriculum…

  15. Teaching for Understanding in Engineering Education

    Directory of Open Access Journals (Sweden)

    Hants Kipper


    Full Text Available The article introduces effective teaching strategies and models suitable for teaching engineering, implemented at Estonian Centre for Engineering Pedagogy. Introduced models are designed to capitalize deep understanding and critical thinking in teaching engineering. Accordingly students will be able to explain, find evidence and examples, generalise, apply, analogise and represent a topic in a new way. At least four different kinds of knowledge are essential for expert teaching: knowledge of content; pedagogical content knowledge; general pedagogical knowledge; and knowledge of learners and learning. The goal of the article is to help engineering teachers acquire knowledge in each of these areas.;

  16. Early understanding and production of graphic symbols. (United States)

    Callaghan, T C


    Young children's ability to understand and produce graphic symbols within an environment of social communication was investigated in two experiments. Children aged 2, 3, and 4 years produced graphic symbols of simple objects on their own, used them in a social communicative game, and responded to experimenter's symbols. In Experiment 1 (N = 48), 2-year-olds did not effectively produce symbols or use the experimenter's symbols in the choice task, whereas 3- and 4-year-olds improved their drawings following the game and performed above chance with the experimenter's symbols. Ability to produce an effective graphic symbol was correlated with success on a task that measured understanding of the experimenter's symbols, supporting the claim that children's ability to produce a graphic symbol rests on the understanding of the symbolic function of pictures. In Experiment 2, 32 children aged 3 and 4 years improved their third set of drawings when they received feedback that their drawings were not effective communications. The results suggest that production and understanding of graphic symbols can be facilitated by the same social factors that improve verbal symbolic abilities, thereby raising the question of domain specificity in symbolic development.

  17. Japanese Children's Understanding of Notational Systems (United States)

    Takahashi, Noboru


    This study examined Japanese children's understanding of two Japanese notational systems: "hiragana" and "kanji". In three experiments, 126 3- to 6-year-olds were asked to name words written in hiragana or kanji as they appeared with different pictures. Consistent with Bialystok ("Journal of Experimental Child…

  18. Understanding and Managing Menopause | NIH MedlinePlus the Magazine (United States)

    ... of this page please turn Javascript on. Feature: Menopause: A Woman's Change of Life Understanding and Managing Menopause Past Issues / Spring 2013 Table of Contents Menopause, or the "change of life," is different for each woman. For ...

  19. Understanding Eating Disorders, Anorexia, Bulimia, and Binge-Eating (United States)

    ... Navigation Bar Home Current Issue Past Issues Understanding Eating Disorders Past Issues / Spring 2008 Table of Contents For ... this page please turn Javascript on. Photo: iStock Eating disorders, such as anorexia nervosa, bulimia nervosa, and binge ...

  20. Understanding Memory Loss | NIH MedlinePlus the Magazine (United States)

    ... of this page please turn Javascript on. Feature: Memory & Forgetfulness Understanding Memory Loss Past Issues / Summer 2013 Table of Contents ... weeks at a time. Some Treatable Causes of Memory Loss As we age, our bodies change, including ...

  1. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available ... Reporting & Auditing Grant Transfer Grant Closeout Contracts & Small Business Training Cancer Training at NCI (Intramural) Funding for ... disease will go for you is called prognosis. It can be hard to understand what prognosis means ...

  2. Understanding health insurance plans (United States)

    ... Understanding health insurance plans To use the sharing features on this ... for you and your family. Types of Health Insurance Plans Depending on how you get your health ...

  3. Thermometers: Understand the Options (United States)

    ... the options Thermometers come in a variety of styles. Understand the different types of thermometers and how ... MA. Fever in infants and children: Pathophysiology and management. Accessed July 23, ...

  4. Understanding cardiovascular disease (United States)

    ... page: // Understanding cardiovascular disease To use the sharing features on this page, ... lead to heart attack or stroke. Types of Cardiovascular Disease Coronary heart disease (CHD) is the most common ...

  5. Tinnitus: Understanding the Facts (United States)

    American Tinnitus Association Donate Become A Member Member Login Find A Provider Search form Search Menu Close Understanding The Facts Managing Your Tinnitus Research Toward A Cure About Us Initiatives News & ...

  6. Understanding the New Economy. (United States)

    Morrell, Louis R.


    Asserts that while the Nasdaq bubble did burst, the new economy is real and that failure to understand the rules of the digital economy can lead to substandard investment portfolio performance. Offers guidelines for higher education institutional investors. (EV)

  7. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available ... side effects from the cancer treatments you received. Video Series This video series offers the perspectives of ... care teams (PDF-210KB). Understanding Your Cancer Prognosis Video View this video on YouTube. Three cancer patients ...

  8. Understanding the DASH diet (United States)

    ... Understanding the DASH diet To use the sharing features on this page, please enable JavaScript. The DASH diet is low in salt and rich in fruits, ...

  9. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available ... Managing Cancer Care Finding Health Care Services Costs & Medical Information Advance Directives Using Trusted Resources Understanding Cancer ... Care Finding Health Care Services Managing Costs and Medical Information Advance Directives Using Trusted Resources Cancer Types ...

  10. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available ... Care Finding Health Care Services Costs & Medical Information Advance Directives Using Trusted Resources Understanding Cancer What Is ... Health Care Services Managing Costs and Medical Information Advance Directives Using Trusted Resources Cancer Types Adolescents and ...

  11. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available ... Research Managing Cancer Care Finding Health Care Services Costs & Medical Information Advance Directives Using Trusted Resources Understanding ... Managing Cancer Care Finding Health Care Services Managing Costs and Medical Information Advance Directives Using Trusted Resources ...

  12. Understanding the Opioid Epidemic (United States)

    ... Search Form Controls Cancel Submit Search The CDC Opioid Overdose Note: Javascript is disabled or is not ... message, please visit this page: About . Opioid Overdose Opioid Basics Understanding the Epidemic Commonly Used ...

  13. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available ... doctor to give you an accurate prognosis. Understanding the Difference Between Cure and Remission Cure means that ... about her colorectal cancer prognosis. Diving Out of the Dark View this video on YouTube. Andrew wants ...

  14. Understanding your hospital bill (United States)

    ... Understanding your hospital bill To use the sharing features on this ... help you save money. Charges Listed on Your Hospital Bill A hospital bill will list the major ...

  15. Understanding Blood Pressure Readings (United States)

    ... Artery Disease Venous Thromboembolism Aortic Aneurysm More Understanding Blood Pressure Readings Updated:Feb 19,2018 What do your ... this chart: English | Spanish | Traditional Chinese Enter Your Blood Pressure Systolic mm Hg (upper #) Diastolic mm Hg (lower #) ...

  16. Content Marketing Practices in Finland


    Suuronen, Toni


    The purpose of this study is to draw attention to increasingly important business phenomenon of content marketing. This paper defines content marketing, identifies its key elements and phases, and explores content marketing practices. The theorethical part is based on Pam Didner's 4P model that describes the stages of content marketing cycle: plan, produce, promote and perfect. The empirical part of the study is based on semi-structured interviews of seasoned content marketing professionals t...

  17. Movimentos sociais e eleições: por uma compreensão mais ampla do contexto político da contestação Social movements and elections: toward a broader understanding of the political context of contention

    Directory of Open Access Journals (Sweden)

    Doug Mcadam


    Full Text Available Por que duas literaturas cognatas - estudos eleitorais e de movimentos sociais - seguem trajetórias paralelas e pouco dialogam? E o que se pode fazer para conectá-las no futuro? Partindo de seu trabalho com Charles Tilly sobre as dinâmicas do confronto (Dynamics of Contention, 2001, Dough McAdam e Sydney Tarrow analisam as conexões entre movimentos sociais e eleições, propõem um conjunto articulado de vínculos entre eleições e movimentos sociais e aplicam sua abordagem a um exame preliminar das relações entre eleições, movimentos e políticas de confronto racial nos Estados Unidos.Why do two cognate literatures - social movements and electoral studies -travel along parallel paths with little conversation between them? And what can be done to connect them in the future? Drawing ontheir work with the late Charles Tilly on Dynamics of Contention (2001, Doug McAdam and Sidney Tarrow examine the reciprocal links between movements and elections, propose a mechanism-based set of linkages between elections and social movements, and apply their approach in a preliminary examination of the relations between elections, movements and the politics of racial contention in the United States.

  18. Understanding Conflict?...Maybe!


    Anthony P. Johnson


    The premise of this paper is the study in the field of conflict andconflict resolution and that conflict and conflict resolution are usefulareas of focus in order to better understand human behavior. Additionally,I will present data that will highlight the notion that conflict is not in itselfa bad thing and that conflict has the capability to be utilized as a vehiclefor understanding the many contradictions that are necessarily present inour efforts to be social beings.

  19. Understanding Family Diversity


    Knowles, G


    This essential text will help students and those already working with children to understand both theoretically and practically, what may constitute a ‘family’. It explores how to build relationships with a child’s family to ensure early years settings and schools are working in partnership with children’s home environments, thereby supporting the best possible learning outcomes for children. It will help the reader to develop their skills, knowledge and understanding of their professional pr...

  20. Free Flowing Content

    DEFF Research Database (Denmark)

    Cass, Andrew Knox; Kravchenko, Mariia


    Higher education institutions are moving to exploit information andcommunication technologies by increasing the use of videos both online and inclass. This is led, by definition, by ‘early adopters’ and most of the research intothis process reflects this. Increasingly, institutions are making...... do not secure theintegrity of the learning. This paper sets out the methods used to assist teacherstake the maximum benefit of their existing content as presentation style lecturesand utilize them for video recording suitable for both flipped and online classes.A central theme is removing the fear...

  1. Determining gold content

    International Nuclear Information System (INIS)

    Clayton, C.G.; Wormald, M.R.


    A method for determining the gold content of a material, comprises irradiating a body of the material with neutrons and determining the intensity of γ-rays having an energy of 279 keV arising from the reaction 179 Au(nn') 179 Au → 279 keV. The apparatus has means for conveying the materials past an assembly, which has a neutron source, which does not produce neutrons having sufficient energy to excite fast neutron reactions in non-auriferous constituents. (author)

  2. Nuclear Test-Experimental Science

    International Nuclear Information System (INIS)

    Struble, G.L.; Donohue, M.L.; Bucciarelli, G.; Hymer, J.D.; Kirvel, R.D.; Middleton, C.; Prono, J.; Reid, S.; Strack, B.


    Fiscal year 1988 has been a significant, rewarding, and exciting period for Lawrence Livermore National Laboratory's nuclear testing program. It was significant in that the Laboratory's new director chose to focus strongly on the program's activities and to commit to a revitalized emphasis on testing and the experimental science that underlies it. It was rewarding in that revolutionary new measurement techniques were fielded on recent important and highly complicated underground nuclear tests with truly incredible results. And it was exciting in that the sophisticated and fundamental problems of weapons science that are now being addressed experimentally are yielding new challenges and understanding in ways that stimulate and reward the brightest and best of scientists. During FY88 the program was reorganized to emphasize our commitment to experimental science. The name of the program was changed to reflect this commitment, becoming the Nuclear Test-Experimental Science (NTES) Program

  3. Brain microdialysis and its applications in experimental neurochemistry. (United States)

    Anderzhanova, Elmira; Wotjak, Carsten T


    Abstract Microdialysis is one of the most powerful neurochemistry techniques, which allows the monitoring of changes in the extracellular content of endogenous and exogenous substances in the brain of living animals. The strength as well as wide applicability of this experimental approach are based on the bulk theory of brain neurotransmission. This methodological review introduces basic principles of chemical neurotransmission and emphasizes the difference in neurotransmission types.Clear understanding of their significance and degree of engagement in regulation of physiological processes is an ultimate prerequisite not only for choosing an appropriate method of monitoring for interneuronal communication via chemical messengers but also for accurate data interpretation. The focus on the processes of synthesis/metabolism, receptor interaction/neuronal signaling or the behavioral relevance of neurochemical events sculpts the experiment design. Brain microdialysis is an important method for examining changes in the content of any substances, irrespective of their origin, in living animals. This article compares contemporary approaches and techniques that are used for monitoring neurotransmission (including in vivo brain microdialysis, voltammetric methods, etc). We highlight practical aspects of microdialysis experiments in particular to those researchers who are seeking to increase the repertoire of their experimental techniques with brain microdialysis.

  4. Method Determining the Contents of the Contract

    Directory of Open Access Journals (Sweden)

    Agus Yudha Hernoko


    Full Text Available The contents of the contract are primarily determined by what the real mutually agreed upon by the parties. By interpreting some certain statements, in this case to determine its meaning, to be clear based on what the parties committed themselves. Why is the interpretation required? In facts, on the many cases provided a valuable lesson, how many commercial disputes arise when the performance of the contract. The dispute begins when the parties have a different understanding of the statement that they use in the contract. Indeed, businesses are very familiar with the business processes that they do, but at the time of the business process are set forth in the contract language and designed by those who do not understand the legal aspects of the contract, the contract can be ascertained open possibility for disputes. The power of contract binding (the contents of the agreement toward to the characteristic and the wide spectrum of the rights and obligations contractually, basically a contract represents the power of performance among others in order implementing the rights and obligations of the parties. As an instrument to understand the contract, the method of determining the content of the contract (e.g., through interpretation, autonomous and heteronomous factors, further can be used to assess the reciprocation of rights and obligations in a meaningful and proportional contractual relationship.

  5. Probing Student Understanding of Scientific Thinking in the Context of Introductory Astrophysics (United States)

    Steinberg, Richard N.; Cormier, Sebastien; Fernandez, Adiel


    Common forms of testing of student understanding of science content can be misleading about their understanding of the nature of scientific thinking. Observational astronomy integrated with related ideas of force and motion is a rich context to explore the correlation between student content knowledge and student understanding of the scientific…

  6. The production of understanding. (United States)

    Link, Bruce G


    While there is little doubt that sociological theory and research has had an important impact on the way people think about health and health care, mental health and medical sociologists are often confronted with challenges concerning the utility of the work that they do. Among the doubters are deans, funding agencies and family members. We are challenged by the ascendency of biological interpretations of human behaviors, by the incompatibility between the contextual view we prefer and the very strong individualistic orientation of our culture, and by the fact that we do not have an applied arm that trains the professionals who treat health and mental-health conditions. How do we respond to this challenge? The title of this paper gives a short answer: "The Production of Understanding." I propose that a powerful but under-recognized value of our work is the generation of explanations about health and mental health matters that help people understand the other side of an "us"/"them" divide. We produce understanding in a context in which misunderstanding is regularly constructed by powerful people who offer victim-blaming explanations for the circumstances experienced by people with less power. The production of understanding serves as an important counterbalance to this tendency. Our work shapes the way people think about problems related to health and mental health, limits the power of inaccurate victim-blaming accounts and provides understanding about why health and mental health are mal-distributed among people from different social circumstances.

  7. Ideas and Approaches on “Construction of High Level Simulation Experimental Teaching Center of Virtual Chemical Laboratory” (United States)

    Zhang, Yunshen


    With the spiritual guidance of the Circular on the Construction of National Virtual Simulation Experimental Teaching Center by the National Department of Education, according to the requirements of construction task and work content, and based on the reality of the simulation experimental teaching center of virtual chemical laboratory at Tianjin University, this paper mainly strengthens the understanding of virtual simulation experimental teaching center from three aspects, and on this basis, this article puts forward specific construction ideas, which refer to the “four combinations, five in one, the optimization of the resources and school-enterprise cooperation”, and on this basis, this article has made effective explorations. It also shows the powerful functions of the virtual simulation experimental teaching platform in all aspects by taking the synthesis and analysis of organic compounds as an example.

  8. Understanding Sex for Sale

    DEFF Research Database (Denmark)

    This book Understanding Sex for Sale: Meanings and Moralities of Sexual Commerce is dedicated to the exploration of the ways in which sex prostitution, sex work or sex for sale are taken for granted by particularly looking at how the relation between sex and money is interpreted and enacted....... This interdisciplinary book aims to understand how prostitution, sex work or sex for sale are defined, delineated, contested and understood in different places and times. The book offers contributions from a number of scholars who, based on their on their own research, discuss on going theoretical issues and analytical...... challenges Some chapters focuses on how prostitution, sex work or sex for sale have been regulated by the authorities and what understandings this regulation builds on. Other chapters investigate the experiences of the sex workers and sex buyers asking how these actors adjust to or resist the categorisation...

  9. [Vitamins in rat experimental diets]. (United States)

    Kodentsova, V M; Beketova, N A; Vrzhesinskaia, O A


    A comparison of full semisynthetic diets used in different laboratories has shown that its vitamin content covers physiological requirements of rats in these micronutrients. The significant fluctuations in group B vitamin concentrations may take place when one uses brewer's yeast as a source of these vitamins. A preliminary assessment of vitamin content in brewer's yeasts is required in this case. An essential contribution of basic components in diet vitamin content must be taken in consideration when one creates a vitamin-deficient diet. Casein contains substantial amounts of group B vitamins and vitamin D. Therefore decontamination of casein from water and / or fat-soluble vitamins or the use of commercial purified casein is required. Vegetable oils are usually used as a fatty component of a diet and they simultaneously serve as an additional source of vitamin E. A choice of naturally containing vitamin E oil as a fat component of a diet is crucial for the creating an alimentary deficiency of vitamin E. The content of fat-soluble vitamins in the diet of control group (group of comparison) and vitamin level in the diet of experimental group of animals must be equivalent in investigations with modified (quality and quantitative) fat diet component. Caloric restriction by simple reducing of food without increasing the amount of vitamins to an adequate level is incorrect. With these considerations in mind proper attention to the equivalence of vitamin content in the diet of animals in experimental and control groups should be paid during experiments scheduling. Otherwise, the studies carried out under deficient or excessive intake of vitamins can lead to incorrect interpretation of the results and difficulties in their comparison with the data obtained under different conditions.

  10. The Power of the Provocative: Exploring World History Content (United States)

    Ashkettle, Bryan L.


    This study addresses how my freshman world history students come to understand controversial issues as provocative within the secondary social studies classroom, and in what ways does their engagement with provocative issues influence their understanding of the content and the world around them. In addition, this research study seeks to discover…

  11. Understanding pastoral mobility

    DEFF Research Database (Denmark)

    Adriansen, Hanne Kirstine


    Based on a case study from Sahelian Senegal, this paper analyses how various actors perceive the importance of pastoral mobility and presents issues of importance for understanding the use of mobility among Fulani of Ferlo. One knowledge system is a scientific one, the 'new rangeland paradigm...... territory, which they consider their place, but are unwilling to employ large-scale mobility themselves. Mobility is not of importance for their ethnic identity and some use paid herders to care for their livestock. By looking at both knowledge systems, we achieve a better understanding of pastoral mobility...

  12. Radioactivity content of books

    International Nuclear Information System (INIS)

    Lalit, B.Y.; Shukla, V.K.; Ramachandran, T.V.


    The natural and fallout radioactivity was measured in a large number of books produced in various countries after 1955. Results of these measurements showed that the books contained radioactivity due to fallout 137 Cs and 226 Ra, 228 Th and 40 K radioisotopes of primordial origin. Books printed in the U.S.A. had low radioactivity of 40K and 226 Ra origin compared to books printed in the European subcontinent. Books printed during high fallout rate (1962-64) or thereafter did not exhibit any significantly higher 137 Cs levels. The maximum radiation dose to the eyes calculated for the radioactivity content of the books was 0.8 μR/hr and the minimum was 0.07 μR/hr; most of the books were in the range 0.3-0.5 μR/hr. (U.K.)

  13. Nostalgia: content, triggers, functions. (United States)

    Wildschut, Tim; Sedikides, Constantine; Arndt, Jamie; Routledge, Clay


    Seven methodologically diverse studies addressed 3 fundamental questions about nostalgia. Studies 1 and 2 examined the content of nostalgic experiences. Descriptions of nostalgic experiences typically featured the self as a protagonist in interactions with close others (e.g., friends) or in momentous events (e.g., weddings). Also, the descriptions contained more expressions of positive than negative affect and often depicted the redemption of negative life scenes by subsequent triumphs. Studies 3 and 4 examined triggers of nostalgia and revealed that nostalgia occurs in response to negative mood and the discrete affective state of loneliness. Studies 5, 6, and 7 investigated the functional utility of nostalgia and established that nostalgia bolsters social bonds, increases positive self-regard, and generates positive affect. These findings demarcate key landmarks in the hitherto uncharted research domain of nostalgia.

  14. Multimedia content analysis

    CERN Document Server

    Ohm, Jens


    This textbook covers the theoretical backgrounds and practical aspects of image, video and audio feature expression, e.g., color, texture, edge, shape, salient point and area, motion, 3D structure, audio/sound in time, frequency and cepstral domains, structure and melody. Up-to-date algorithms for estimation, search, classification and compact expression of feature data are described in detail. Concepts of signal decomposition (such as segmentation, source tracking and separation), as well as composition, mixing, effects, and rendering, are discussed. Numerous figures and examples help to illustrate the aspects covered. The book was developed on the basis of a graduate-level university course, and most chapters are supplemented by problem-solving exercises. The book is also a self-contained introduction both for researchers and developers of multimedia content analysis systems in industry. .

  15. Burnout syndrome: understanding of medical teaching professionals


    Jaqueline Brito Vidal Batista; Thaíza Ferreira Costa; Jocerlânia Maria Dias de Morais; Eveline de Oliveira Barros; Patrícia Serpa de Souza Batista; Márcia Adriana Dias Meirelles Moreira; Jessyka Cibelly Minervina da Costa Silva; Débora Rodrigues Alves de Lima; Ana Hévila Marinho Bezerra; Irany Carvalho da Silva


    This study aimed to investigate the understanding of medical teaching professionals about Burnout Syndrome. This is a qualitative, exploratory study, consisting of ten teaching physicians, who work at the hospital of a higher education institution. The data were collected from May to June 2013, through a form with questions pertinent to the proposed research objective, after approval by the Research Ethics Committee (Protocol No. 84022), and analyzed qualitatively, through the content analysi...

  16. experimental evaluation experimental evaluation of alternative mix

    African Journals Online (AJOL)


    This paper presents a comparison of seawater and laboratory brine on concrete using experimental methods. using experimental methods. using experimental methods. The seawater employed was obtained from Escravos in the coast of Atlantic Ocean in Nigeria. A concrete mix of. 1:2:4and water/cement ratio of 0.6 was ...

  17. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available ... Your Diagnosis Research Understanding Cancer Prognosis Oncologist Anthony L. Back, M.D., a national expert on doctor- ... Centered Approach View this video on YouTube. Anthony L. Back, M.D., coaches other oncologists about how ...

  18. Understanding Inclusion in Cyprus (United States)

    Mamas, Christoforos


    This paper provides a framework for understanding inclusion in Cyprus. The evidence base is the result of a six-month qualitative research study in five Cypriot mainstream primary schools. Despite the rhetoric in favour of inclusion, it seems that the Cypriot educational system is still highly segregating in its philosophy and does not fully…

  19. Understanding regime shifts

    DEFF Research Database (Denmark)

    Heymann, Matthias; Nielsen, Kristian Hvidtfelt

    ”. Danish wind power development is all the more surprising, as the innovation process in wind technology was carried to a large extent by non-academic craftsmen and political activists. Many features of this innovation story have been investigated and that research makes it possible to summarize...... the current understanding of the regime shift....

  20. Understanding land administration systems

    DEFF Research Database (Denmark)

    P. Williamson, Ian; Enemark, Stig; Wallace, Judy


    This paper introduces basic land administration theory and highlights four key concepts that are fundamental to understanding modern land administration systems. Readers may recall the first part of the paper in October issue of Coordinates. Here is the concluding part that focuses on the changing...

  1. Understanding the bubbles

    DEFF Research Database (Denmark)

    Turcan, Romeo V.

    all boils down to the role pricing plays vis-à-vis the emergence of a new venture and its perceived value. Being in the midst of the global economic crisis provides us with a unique opportunity to refine the proposed model, especially by understanding its temporal and contextual boundaries....

  2. Teachers' Understandings of Probability (United States)

    Liu, Yan; Thompson, Patrick


    Probability is an important idea with a remarkably wide range of applications. However, psychological and instructional studies conducted in the last two decades have consistently documented poor understanding of probability among different populations across different settings. The purpose of this study is to develop a theoretical framework for…

  3. Understanding Ocean Acidification (United States)

    National Oceanic and Atmospheric Administration, 2011


    This curriculum module is designed for students who are taking high school chemistry. Students should already have some experience with the following: (1) Understanding and reading the pH scale; (2) Knowledge of the carbon cycle; (3) Using scientific notation to express large and small values; and (4) Reading chemical equations. This curriculum…

  4. Phun Week: Understanding Physiology (United States)

    Limson, Mel; Matyas, Marsha Lakes


    Topics such as sports, exercise, health, and nutrition can make the science of physiology relevant and engaging for students. In addition, many lessons on these topics, such as those on the cardiovascular, respiratory, and digestive systems, align with national and state life science education standards. Physiology Understanding Week (PhUn…

  5. Understanding Organizational Advantage

    DEFF Research Database (Denmark)

    Stea, Diego; Linder, Stefan; Foss, Nicolai Juul


    The attention-based view (ABV) of the firm highlights the role of decision makers’ attention in firm behavior. The ABV vastly improves our understanding of decision makers’ focus of attention; how that focus is situated in an organization’s procedural and communication channels; and how the distr......The attention-based view (ABV) of the firm highlights the role of decision makers’ attention in firm behavior. The ABV vastly improves our understanding of decision makers’ focus of attention; how that focus is situated in an organization’s procedural and communication channels; and how...... the distribution of the focus of attention among decision makers participating in those procedural and communication channels affects their understanding of a situation, their motivation to act, and, ultimately, their behavior. Significant progress has been made in recent years in refining and extending the ABV....... However, the role of individual differences in the capacity to read other people’s desires, intentions, knowledge, and beliefs that is, the theory of mind (ToM) has remained on the sidelines. The ToM is a natural complement to the ABV. In this study, we explore how the ToM allows for an understanding...

  6. Understanding ADHD through entification

    DEFF Research Database (Denmark)

    Nielsen, Mikka

    with adults diagnosed with ADHD, I illustrate how the process of entification (transforming a trait, temperament, emotion, or some other psychological phenomenon into a thing or agent) can be a way to understand, accept and handle the symptoms of ADHD. In this context, ADHD is perceived on the one hand...

  7. Measuring Spreadsheet Formula Understandability

    NARCIS (Netherlands)

    Hermans, F.F.J.; Pinzger, M.; Van Deursen, A.


    Spreadsheets are widely used in industry, because they are flexible and easy to use. Often they are used for business-critical applications. It is however difficult for spreadsheet users to correctly assess the quality of spreadsheets, especially with respect to the understandability.

  8. Understanding Cancer Prognosis

    Medline Plus

    Full Text Available ... 1-800-4-CANCER Live Chat Publications Dictionary Menu Contact Dictionary Search About Cancer Causes and Prevention ... source and a link to this page included, e.g., “Understanding Cancer Prognosis was originally published by ...

  9. Text understanding for computers

    NARCIS (Netherlands)

    Kenter, T.M.


    A long-standing challenge for computers communicating with humans is to pass the Turing test, i.e., to communicate in such a way that it is impossible for humans to determine whether they are talking to a computer or another human being. The field of natural language understanding — which studies

  10. Interviewing to Understand Strengths (United States)

    Hass, Michael R.


    Interviewing clients about their strengths is an important part of developing a complete understanding of their lives and has several advantages over simply focusing on problems and pathology. Prerequisites for skillfully interviewing for strengths include the communication skills that emerge from a stance of not knowing, developing a vocabulary…

  11. On the metaphysics of experimental physics

    CERN Document Server

    Rogers, K


    This provocative and critical work addresses the question of why scientific realists and positivists consider experimental physics to be a natural and empirical science. Taking insights from contemporary science studies, continental philosophy, and the history of physics, this book describes and analyses the metaphysical presuppositions that underwrite the technological use of experimental apparatus and instruments to explore, model, and understand nature. By revealing this metaphysical foundation, the author questions whether experimental physics is a natural and empirical science at all.


    Directory of Open Access Journals (Sweden)

    Tengku Nor Rizan Tengku Mohamad Maasum


    Full Text Available Abstract: Advocates of the content-based approach believed that a language can be learnt effectively when it is the medium of instruction rather than just a subject.  Integrating English and content as part of instruction has become one of the cornerstones of second language pedagogy. Researchers claimed that there are many benefits of integrating English and content instruction.  Among the benefits are the increase in students’ interest with content themes, meaningful input and understanding. In 2003, the Malaysian Ministry of Education introduced the teaching and learning of science and mathematics in English for Year One, Form One and Lower Six Form in all government public schools. This paper describes the challenges faced by teachers when they are required to teach content subjects such as science and mathematics in English.  The focus of the paper is on the teachers’ pedagogical skills  and content knowldge which comprises subject matter content, pedagogical approach, classroom management, use of resources, assessment, preparation of teaching materials, managing students, teachers’ compensatory communication strategies, use of first language and teachers’ perspectives of teaching content subjects in English. Data were obtained from a self-report questionnaire administered to 495 secondary school teachers in West Malaysia. Results from the study provide implications for school administrators in making decisions in assignment of  capable teachers to teach the various levels of classes. Suggestions for teacher self-development and life-long learning efforts are also provided.   Key words: Content-based instruction, ESL instruction, second language, first language and second language pedagogy

  13. Numerical and experimental determination of surface temperature and moisture evolution in a field soil (United States)

    Akinyemi, Olukayode D.; Mendes, Nathan


    Knowledge about the dynamics of soil moisture and heat, especially at the surface, provides important insights into the physical processes governing their interactions with the atmosphere, thereby improving the understanding of patterns of climate dynamics. In this context the paper presents the numerical and field experimental results of temperature and moisture evolution, which were measured on the surface of a sandy soil at Abeokuta, south-western Nigeria. An unconditionally stable numerical method was used, which linearizes the vapour concentration driving-potential term giving the moisture exchanged at the boundaries in terms of temperature and moisture content, and simultaneously solves the governing equations for each time step. The model avoids stability problems and limitations to low moisture contents and the usual assumption of constant thermal conductivity. Instantaneous temperature measurements were made at the surface using a thermocouple, while the gravimetric method was employed to determine the volumetric water contents at some specific hours of the experimental period. The observed experimental data compared fairly well with the predicted values, with both having correlation coefficients greater than 0.9 and consequently following a common diurnal trend. The sensitivity of the model was very high to the choice of simulation parameters, especially grid size refinement and time step. While the model underestimated the soil moisture content at 6 a.m. and 10 p.m., the measured temperatures were however overestimated. When compared to moisture content, average errors for temperature were low resulting in a minimal absolute difference in amplitude of 0.81 °C.

  14. Understanding Games as Played

    DEFF Research Database (Denmark)

    Leino, Olli Tapio


    Researchers interested in player’s experience would assumedly, across disciplines, agree that the goal behind enquiries into player’s experience is to understand the how games’ features end up affecting the player’s experience. Much of the contemporary interdisciplinary research into player......’s experience leans toward the empirical-scientific, in the forms (neuro)psychology, sociology and cognitive science, to name a few. In such approaches, for example demonstrating correlation between physiological symptoms and an in-game event may amount to ‘understanding’. However, the experience of computer...... game play is a viable topic also for computer game studies within the general tradition of humanities. In such context, the idea of ‘understanding an experience’ invites an approach focusing on the experienced significance of events and objects within computer game play. This focus, in turn, suggests...

  15. Understanding Video Games

    DEFF Research Database (Denmark)

    Heide Smith, Jonas; Tosca, Susana Pajares; Egenfeldt-Nielsen, Simon

    From Pong to PlayStation 3 and beyond, Understanding Video Games is the first general introduction to the exciting new field of video game studies. This textbook traces the history of video games, introduces the major theories used to analyze games such as ludology and narratology, reviews...... the economics of the game industry, examines the aesthetics of game design, surveys the broad range of game genres, explores player culture, and addresses the major debates surrounding the medium, from educational benefits to the effects of violence. Throughout the book, the authors ask readers to consider...... larger questions about the medium: * What defines a video game? * Who plays games? * Why do we play games? * How do games affect the player? Extensively illustrated, Understanding Video Games is an indispensable and comprehensive resource for those interested in the ways video games are reshaping...

  16. Understanding Video Games

    DEFF Research Database (Denmark)

    Heide Smith, Jonas; Tosca, Susana Pajares; Egenfeldt-Nielsen, Simon

    From Pong to PlayStation 3 and beyond, Understanding Video Games is the first general introduction to the exciting new field of video game studies. This textbook traces the history of video games, introduces the major theories used to analyze games such as ludology and narratology, reviews...... larger questions about the medium: * What defines a video game? * Who plays games? * Why do we play games? * How do games affect the player? Extensively illustrated, Understanding Video Games is an indispensable and comprehensive resource for those interested in the ways video games are reshaping...... entertainment and society. A companion website ( features student resources including discussion questions for each chapter, a glossary of key terms, a video game timeline, and links to other video game studies resources for further study....

  17. Understanding China's Transformations

    DEFF Research Database (Denmark)

    Li, Xing

    The objective of this paper is to offer a framework of understanding the dialectical nexus between China's internal evolutions and the external influences with a focus on the century-long "challenge-response" dynamism. That is to explore how external factors helped shaping China's internal...... transformations, i.e. how generations of Chinese have been struggling in responding to the external challenges and attempting to sinicize external political ideas in order to change China from within. Likewise, it is equally important to understand how China's inner transformation contributed to reshaping...... the world. Each time, be it China's dominance or decline, the capitalist world system has to adjust and readjust itself to the opportunities and constraints brought about by the "China factors"....


    Directory of Open Access Journals (Sweden)

    Romanova OA


    Full Text Available Introduction. With the transport links development there is rather important issue respiratory viral infections spread, especially influenza. The only method controlling influenza is vaccination. Search and development effective and safe vaccines is important. Material and methods. In base SO "Mechnikov Institute Microbiology and Immunology National Ukrainian Academy Medical Sciences" in the scientific theme "Developing new approaches to creating viral vaccines and study specific activity depending of type and degree component`s modification" was created several experimental influenza vaccine with subsequent component`s modification for selecting the most optimal pattern of safety and immunogenicity. In assessing the influenza vaccine safety is using a few criteria, including, reactivity, as measured by the frequency of local and systemic adverse (negative effects, which due to its introduction, and for lipid content drugs, ability to influence oxidation processes. At present study phase was determined: a systemic reaction and local reaction of delayed-type hypersensitivity (foot pad swelling assay;b lipids and proteins peroxidation processes after administration officinal and experimental vaccines (content protein’s carbonyl groups, lipid’s hydroperoxides, activity of glutathione-peroxidase.Study objects were trivalent seasonal influenza vaccine, "Vaxigrip" (Sanofi Pasteur, S.A., France, "Inflexal V" (Biotech Ltd. Berne, Switzerland and experimental vaccine samples. Highest immunogenicity vaccines had undergone improvements and modifications using adjuvant systems and acylation influenza proteins. Liposomes 2 – the experimental influenza vaccine with a liposome negative charge and antigenic composition like split vaccines "Vaksihryp". Liposomes 2.1 - the adjuvantexperimental influenza vaccine with modifications liposomal components (etoniy and chlorophyllipt molecules embedded in liposomal membrane. Liposomes 2.2 - the adjuvant

  19. Experimental Summary and Outlook

    Energy Technology Data Exchange (ETDEWEB)

    Peter Bosted


    A brief experimental overview of the workshop is given, with emphasis on polarized targets from the experimental equipment perspective, and kinematic coverage, precision, and newly investigated channels from the experimental results perspective.

  20. BENSC. Experimental reports 1994

    International Nuclear Information System (INIS)

    Kirschbaum, Y.; Gast, H.; Michaelsen, R.


    This volume contains the guest groups' experimental reports describing experimental work carried out on the Berlin Scattering Center in 1994. These experimental reports are intended as interim summaries. (HP)

  1. BENSC experimental reports 1993

    International Nuclear Information System (INIS)

    Kirschbaum, Y.; Michaelsen, R.


    This volume contains the guest groups' experimental reports describing experimental work carried out on the Berlin Scattering Center in 1993. These experimental reports are intended as interim summaries. (HP)

  2. Intention understanding in autism.

    Directory of Open Access Journals (Sweden)

    Sonia Boria

    Full Text Available When we observe a motor act (e.g. grasping a cup done by another individual, we extract, according to how the motor act is performed and its context, two types of information: the goal (grasping and the intention underlying it (e.g. grasping for drinking. Here we examined whether children with autistic spectrum disorder (ASD are able to understand these two aspects of motor acts. Two experiments were carried out. In the first, one group of high-functioning children with ASD and one of typically developing (TD children were presented with pictures showing hand-object interactions and asked what the individual was doing and why. In half of the "why" trials the observed grip was congruent with the function of the object ("why-use" trials, in the other half it corresponded to the grip typically used to move that object ("why-place" trials. The results showed that children with ASD have no difficulties in reporting the goals of individual motor acts. In contrast they made several errors in the why task with all errors occurring in the "why-place" trials. In the second experiment the same two groups of children saw pictures showing a hand-grip congruent with the object use, but within a context suggesting either the use of the object or its placement into a container. Here children with ASD performed as TD children, correctly indicating the agent's intention. In conclusion, our data show that understanding others' intentions can occur in two ways: by relying on motor information derived from the hand-object interaction, and by using functional information derived from the object's standard use. Children with ASD have no deficit in the second type of understanding, while they have difficulties in understanding others' intentions when they have to rely exclusively on motor cues.

  3. Understanding nuclear issues

    Energy Technology Data Exchange (ETDEWEB)

    Marx, G. [Department of Atomic Physics, Eoetvoes Univ., Budapest (Hungary)


    In our days technological progress for the benefit of society is slowed down by the fact that common citizens (opinion-forming media reporters, journalists, furthermore elected decision-makers) are underinformed about basic numerical facts concerning harms and benefits of high technology. Here a comparative risk study is presented about smoking, ozone hole, global warming, and ionizing radiation. This approach has turned out to be successful in educating the youth in Hungary; because school-going teenagers do understand numbers. (author)

  4. Understanding the spermatozoon. (United States)

    Neri, Queenie V; Hu, Jennifer; Rosenwaks, Zev; Palermo, Gianpiero D


    The former perception of the spermatozoon as a delivery device of the male genome has been expanded to include a new understanding of the cell's complex role in fertilization. Once the spermatozoon reaches the oocyte, it triggers egg activation and orchestrates the stages of pre- and post-fertilization in a preprogrammed pattern while tapping the oocyte's resources in an effort to generate a new life.

  5. Understanding Mediation Support


    Lanz, David; Pring, Jamie; von Burg, Corinne; Zeller, Mathias


    Recent decades have witnessed increasing institutionalization of mediation support through the establishment of mediation support structures (MSS) within foreign ministries and secretariats of multilateral organizations. This study sheds light on this trend and aims to better understand the emergence, design and development of different MSS. This study analyzes six MSS, namely those established in the United Nations (UN), the Organization for Security and Co-operation in Europe (OSCE), the Eu...

  6. Understanding nuclear issues

    International Nuclear Information System (INIS)

    Marx, G.


    In our days technological progress for the benefit of society is slowed down by the fact that common citizens (opinion-forming media reporters, journalists, furthermore elected decision-makers) are underinformed about basic numerical facts concerning harms and benefits of high technology. Here a comparative risk study is presented about smoking, ozone hole, global warming, and ionizing radiation. This approach has turned out to be successful in educating the youth in Hungary; because school-going teenagers do understand numbers. (author)

  7. Image Understanding Research (United States)


    Numerlues en Sciences Physiques et Economiques , Collection Methode Mathematiques de l’Informatique, Dunod, 1976. 47 26. P. Saint-Pierre, "Etude Theorique et...overlap since adjacent linear features are being presented. References 1. S. Rubin, "The ARGOS Image Understanding System," Ph.D. thesis, Computer Science ...Techniques," TR 480, Computer Science Center, University of Maryland, September i979. 5. Davis, Larry S. and Azriel Rosenfeld, "Hierarchical Relaxation for

  8. Preschoolers' Recall of Science Content From Educational Videos Presented With and Without Songs (United States)

    Schechter, Rachel L.

    This experimental investigation evaluated the impact of educational songs on a child's ability to recall scientific content from an educational television program. Preschoolers' comprehension of the educational content was examined by measuring children's ability to recall the featured science content (the function of a pulley and its parts) and their use of the precise scientific terms presented in the episode. A total of 91 preschoolers were included (3-5 years old). Clusters of children were randomly assigned to a control group or one of three video groups: (a) Dialogue Only, which did not include a song; (b) Dialogue Plus Lyrics, which included a song; or (c) Lyrics Only, which consisted of a song, played twice. Results from interviews suggested that children from all video groups (lyrics and/or dialogue) were able to explain the form and function of a pulley better than the control group. The data suggested that children from the Lyrics Only group understood the science content because of the visual imagery, not through the information provided in the lyrics. In terms of precise vocabulary terms, significantly more children in the Dialogue Only group recalled at least one precise term from the program compared to the Lyrics Only group. Looking at the interview as a whole, the children's responses suggested different levels of scientific understanding. Children would require additional teacher-led instruction to deepen their scientific understanding and to clarify any misconceptions. This paper discusses implications of these findings for teachers using multi-media tools in the science classroom and producers creating new educational programming for television and other platforms.

  9. Content validity and its estimation

    Directory of Open Access Journals (Sweden)

    Yaghmale F


    Full Text Available Background: Measuring content validity of instruments are important. This type of validity can help to ensure construct validity and give confidence to the readers and researchers about instruments. content validity refers to the degree that the instrument covers the content that it is supposed to measure. For content validity two judgments are necessary: the measurable extent of each item for defining the traits and the set of items that represents all aspects of the traits. Purpose: To develop a content valid scale for assessing experience with computer usage. Methods: First a review of 2 volumes of International Journal of Nursing Studies, was conducted with onlyI article out of 13 which documented content validity did so by a 4-point content validity index (CV! and the judgment of 3 experts. Then a scale with 38 items was developed. The experts were asked to rate each item based on relevance, clarity, simplicity and ambiguity on the four-point scale. Content Validity Index (CVI for each item was determined. Result: Of 38 items, those with CVIover 0.75 remained and the rest were discarded reSulting to 25-item scale. Conclusion: Although documenting content validity of an instrument may seem expensive in terms of time and human resources, its importance warrants greater attention when a valid assessment instrument is to be developed. Keywords: Content Validity, Measuring Content Validity


    Directory of Open Access Journals (Sweden)

    Ovidia IONESCU


    Full Text Available Our intellect characterizes us and helps us make a difference in life. Due to our intellect we can understand the world around us, our personality is shaped and developed and, depending on such development, we can learn new things that are beneficial to us both as individuals and the humankind as a whole. Intellectual property focuses on the intellect and the protection of everything that is a creation, represents an important element of day-to-day life and ensures the adequate progress of things deriving from and related to said aspect. Authors are the creators of intellectual property, and their creation must be protected. Furthermore, they benefit from a protection system, respectively a protection title, as well as patrimonial and non-patrimonial rights in connection with their achieved creation and in full dependence thereupon.

  11. Understanding noninferiority trials

    Directory of Open Access Journals (Sweden)

    Seokyung Hahn


    Full Text Available Noninferiority trials test whether a new experimental treatment is not unacceptably less efficacious than an active control treatment already in use. With continuous improvements in health technologies, standard care, and clinical outcomes, the incremental benefits of newly developed treatments may be only marginal over existing treatments. Sometimes assigning patients to a placebo is unethical. In such circumstances, there has been increasing emphasis on the use of noninferiority trial designs. Noninferiority trials are more complex to design, conduct, and interpret than typical superiority trials. This paper reviews the concept of noninferiority trials and discusses some important issues related to them.

  12. Aerobiology: Experimental Considerations, Observations, and Future Tools


    Haddrell, Allen E.; Thomas, Richard J.


    ABSTRACT Understanding airborne survival and decay of microorganisms is important for a range of public health and biodefense applications, including epidemiological and risk analysis modeling. Techniques for experimental aerosol generation, retention in the aerosol phase, and sampling require careful consideration and understanding so that they are representative of the conditions the bioaerosol would experience in the environment. This review explores the current understanding of atmospheri...

  13. Simulating human behavior for understanding and managing environmental resource use

    NARCIS (Netherlands)

    Jager, Wander; Mosler, Hans Joachim


    Computer simulation allows for the experimental study of dynamic interactions between human behavior and complex environmental systems. Behavioral determinants and processes as identified in social-scientific theory may be formalized in simulated agents to obtain a better understanding of

  14. Understanding metal–insulator transition in sodium tungsten bronze

    Indian Academy of Sciences (India)

    ARPES) and spectro- microscopy studies to understand the metal–insulator transition (MIT) observed in sodium tungsten bronzes, NaxWO3. The experimentally determined band structure is compared with the theoretical calculation based on ...

  15. Problem-Centered Supplemental Instruction in Biology: Influence on Content Recall, Content Understanding, and Problem Solving Ability (United States)

    Gardner, Joel; Belland, Brian R.


    To address the need for effective, efficient ways to apply active learning in undergraduate biology courses, in this paper, we propose a problem-centered approach that utilizes supplemental web-based instructional materials based on principles of active learning. We compared two supplementary web-based modules using active learning strategies: the first used Merrill's First Principles of Instruction as a framework for organizing multiple active learning strategies; the second used a traditional web-based approach. Results indicated that (a) the First Principles group gained significantly from pretest to posttest at the Remember level ( t(40) = -1.432, p = 0.08, ES = 0.4) and at the Problem Solving level ( U = 142.5, N1 = 21, N2 = 21, p = .02, ES = 0.7) and (b) the Traditional group gained significantly from pretest to posttest at the Remember level ( t(36) = 1.762, p = 0.043, ES = 0.6). Those in the First Principles group were significantly more likely than the traditional group to be confident in their ability to solve problems in the future (χ2 (2, N = 40) = 3.585, p = 0.09).

  16. Understanding radioactive waste

    Energy Technology Data Exchange (ETDEWEB)

    Murray, R.L.


    This document contains information on all aspects of radioactive wastes. Facts are presented about radioactive wastes simply, clearly and in an unbiased manner which makes the information readily accessible to the interested public. The contents are as follows: questions and concerns about wastes; atoms and chemistry; radioactivity; kinds of radiation; biological effects of radiation; radiation standards and protection; fission and fission products; the Manhattan Project; defense and development; uses of isotopes and radiation; classification of wastes; spent fuels from nuclear reactors; storage of spent fuel; reprocessing, recycling, and resources; uranium mill tailings; low-level wastes; transportation; methods of handling high-level nuclear wastes; project salt vault; multiple barrier approach; research on waste isolation; legal requiremnts; the national waste management program; societal aspects of radioactive wastes; perspectives; glossary; appendix A (scientific American articles); appendix B (reference material on wastes). (ATT)

  17. Understanding radioactive waste

    International Nuclear Information System (INIS)

    Murray, R.L.


    This document contains information on all aspects of radioactive wastes. Facts are presented about radioactive wastes simply, clearly and in an unbiased manner which makes the information readily accessible to the interested public. The contents are as follows: questions and concerns about wastes; atoms and chemistry; radioactivity; kinds of radiation; biological effects of radiation; radiation standards and protection; fission and fission products; the Manhattan Project; defense and development; uses of isotopes and radiation; classification of wastes; spent fuels from nuclear reactors; storage of spent fuel; reprocessing, recycling, and resources; uranium mill tailings; low-level wastes; transportation; methods of handling high-level nuclear wastes; project salt vault; multiple barrier approach; research on waste isolation; legal requiremnts; the national waste management program; societal aspects of radioactive wastes; perspectives; glossary; appendix A (scientific American articles); appendix B (reference material on wastes)

  18. Educators' understanding of workplace bullying

    Directory of Open Access Journals (Sweden)

    Corene de Wet


    Full Text Available This article looks at educators' understanding of workplace bullying through the lens o a two-dimensional model of bullying. Educators, who were furthering their studies at the University of the Free State, were invited to take part in a study on different types of bullying. Deductive, directed content analysis was used to analyse 59 participants' descriptions of workplace bullying. The study found that the theoretical model provided a valuable framework for studying bullying in this context. The analysis of the educators' descriptions provided the following insights about the relational and organisational foundations of workplace bullying: (1 The relational powerless victims are subjected to public humiliation, disregard, isolation and discrimination. The bullying of educators results in escalating apathy and disempowerment, to the detriment of their professional and private wellbeing. (2 Bullying is likely to occur in schools where organisational chaos reigns. Such schools are characterised by incompetent, unprincipled, abusive leadership, lack of accountability, fairness and transparency. (3 There is interplay between relational powerlessness and organisational chaos, i.e. the absence of principled leadership, accountability and transparency gives rise to workplace bullying.

  19. Aiding Vertical Guidance Understanding (United States)

    Feary, Michael; McCrobie, Daniel; Alkin, Martin; Sherry, Lance; Polson, Peter; Palmer, Everett; McQuinn, Noreen


    A two-part study was conducted to evaluate modern flight deck automation and interfaces. In the first part, a survey was performed to validate the existence of automation surprises with current pilots. Results indicated that pilots were often surprised by the behavior of the automation. There were several surprises that were reported more frequently than others. An experimental study was then performed to evaluate (1) the reduction of automation surprises through training specifically for the vertical guidance logic, and (2) a new display that describes the flight guidance in terms of aircraft behaviors instead of control modes. The study was performed in a simulator that was used to run a complete flight with actual airline pilots. Three groups were used to evaluate the guidance display and training. In the training, condition, participants went through a training program for vertical guidance before flying the simulation. In the display condition, participants ran through the same training program and then flew the experimental scenario with the new Guidance-Flight Mode Annunciator (G-FMA). Results showed improved pilot performance when given training specifically for the vertical guidance logic and greater improvements when given the training and the new G-FMA. Using actual behavior of the avionics to design pilot training and FMA is feasible, and when the automated vertical guidance mode of the Flight Management System is engaged, the display of the guidance mode and targets yields improved pilot performance.

  20. Nuclear magnetic resonance imaging of water content in the subsurface

    Energy Technology Data Exchange (ETDEWEB)

    J. Hendricks; T. Yao; A. Kearns


    Previous theoretical and experimental studies indicated that surface nuclear magnetic resonance (NMR) has the potential to provide cost-effective water content measurements in the subsurface and is a technology ripe for exploitation in practice. The objectives of this investigation are (a) to test the technique under a wide range of hydrogeological conditions and (b) to generalize existing NMR theories in order to correctly model NMR response from conductive ground and to assess properties of the inverse problem. Twenty-four sites with different hydrogeologic settings were selected in New Mexico and Colorado for testing. The greatest limitation of surface NMR technology appears to be the lack of understanding in which manner the NMR signal is influenced by soil-water factors such as pore size distribution, surface-to-volume ratio, paramagnetic ions dissolved in the ground water, and the presence of ferromagnetic minerals. Although the theoretical basis is found to be sound, several advances need to be made to make surface NMR a viable technology for hydrological investigations. There is a research need to investigate, under controlled laboratory conditions, how the complex factors of soil-water systems affect NMR relaxation times.

  1. Astronomical Content in Rongorongo Tablet Keiti

    DEFF Research Database (Denmark)

    Wieczorek, Rafal


    Th e fi eld of rongorongo research: the study of Easter Island’s native script is in a peculiar state at the moment. While relative progress has been made in structural and statistical analysis in the last decades, at the level of both single glyphs as well as entire texts, little to no advanceme...... has been achieved in the actual decipherment. To shed new light on rongorongo research, a hypothesis regarding the contents of tablet Keiti, one of the 25 obtained artifacts, is proposed. Th e content, as well as the meaning, of all but one of these 25 rongorongo texts is still unknown....... In this publication, an interpretation for the recto side of tablet Keiti is presented. It is argued that the tablet contains astronomical observations or instructions regarding the Rapa Nui lunar calendar, and is similar in content to the only other rongorongo text whose function has been partially ascertained......: tablet Mamari. If the calendrical contents of this artifact were confi rmed, this would be a major boost to our understanding of Oceania’s only native script....

  2. Understanding Interest Rate Volatility

    DEFF Research Database (Denmark)

    Volker, Desi

    with and without stochastic volatility to capture the main stylized features of U.S. interest rates. The third essay, \\Variance Risk Premia in the Interest Rate Swap Market", investigates the time-series and cross-sectional properties of the compensation demanded for holding interest rate variance risk. The essays...... are self-contained and can be read independently. There is however a common thread in the themes covered as all essays focus on the understanding of interest rate volatility, its time-variation and main determinants....

  3. Understanding Computational Bayesian Statistics

    CERN Document Server

    Bolstad, William M


    A hands-on introduction to computational statistics from a Bayesian point of view Providing a solid grounding in statistics while uniquely covering the topics from a Bayesian perspective, Understanding Computational Bayesian Statistics successfully guides readers through this new, cutting-edge approach. With its hands-on treatment of the topic, the book shows how samples can be drawn from the posterior distribution when the formula giving its shape is all that is known, and how Bayesian inferences can be based on these samples from the posterior. These ideas are illustrated on common statistic

  4. Understanding Homicide-Suicide. (United States)

    Knoll, James L


    Homicide-suicide is the phenomenon in which an individual kills 1 or more people and commits suicide. Research on homicide-suicide has been hampered by a lack of an accepted classification scheme and reliance on media reports. Mass murder-suicide is gaining increasing attention particularly in the United States. This article reviews the research and literature on homicide-suicide, proposing a standard classification scheme. Preventive methods are discussed and sociocultural factors explored. For a more accurate and complete understanding of homicide-suicide, it is argued that future research should use the full psychological autopsy approach, to include collateral interviews. Copyright © 2016 Elsevier Inc. All rights reserved.

  5. Understanding MARC: Another Look

    Directory of Open Access Journals (Sweden)

    Roy Chang


    Full Text Available 無MARC format has been widely used and discussed in our profession. However, there appear to have a wide spread misunderstanding of its real structure and attributes. This article discuss the needs for us to understand it a little more. Also, it presents the general misconceptions about MARC, the compatibility of MARC, the structure of MARC, standardization and - data communication, and some major issues related to MARC format. In this library automation age, MARC is a key element in library services, and it deserves us to take another look.

  6. Understanding Teen UX

    DEFF Research Database (Denmark)

    Fitton, Daniel; Iversen, Ole Sejer; Bell, Beth


    needs to be understood about this population, from a UX perspective. The theme of this workshop is Building a Bridge to the Future and the aim is to gather together academics and UX practitioners, interested in teen users specifically, in order to discuss experiences, understandings, insights...... and methods that we can use to comprehend teen UX now and explore how this may lead to the creation of better interactive products in the future. The workshop will also foster new collaborations, and define new research agendas to grow the research and literature in this area....

  7. Understanding DSGE models

    CERN Document Server

    Costa Junior, Celso Jose


    While the theoretical development of DSGE models is not overly difficult to understand, practical application remains somewhat complex. The literature on this subject has some significant obscure points. This book can be thought of, firstly, as a tool to overcome initial hurdles with this type of modeling. Secondly, by showcasing concrete applications, it aims to persuade incipient researchers to work with this methodology. In principle, this is not a book on macroeconomics in itself, but on tools used in the construction of this sort of models. It strives to present this technique in a detail

  8. Recent Stirling engine loss - understanding results

    International Nuclear Information System (INIS)

    Tew, R.C.; Thieme, L.G.; Dudenhoefer, J.E.


    For several years, the National Aeronautics and Space Administration and other US Government agencies have been funding experimental and analytical efforts to improve the understanding of Stirling thermodynamic losses. NASA's objective is to improve Stirling engine design capability to support the development of new engines for space power. An overview of these efforts was last given at the 1988 IECEC. Recent results of this research are reviewed

  9. Understanding and Predicting Foam in Anaerobic Digester


    I. R. Kanu; T. J. Aspray; A. J. Adeloye


    As a result of the ambiguity and complexity surrounding anaerobic digester foaming, efforts have been made by various researchers to understand the process of anaerobic digester foaming so as to proffer a solution that can be universally applied rather than site specific. All attempts ranging from experimental analysis to comparative review of other process has not fully explained the conditions and process of foaming in anaerobic digester. Studying the current available ...

  10. Process versus content in eyewitness metamemory monitoring. (United States)

    Robinson, M D; Johnson, J T; Robertson, D A


    Three studies (Ns = 200, 135, and 187 college undergraduates) contrasted process versus content accounts of eyewitness metamemory monitoring. Subjective vividness, a cue related to memory content, was a better predictor of confidence and accuracy than were cues related to the retrieval process. Participants who were asked to recall, rather than recognize, event details displayed greater insight into accuracy, primarily because vividness was a more valid accuracy cue under recall conditions. Results reinforce the value of recall-based protocols for eliciting eyewitness testimony and suggest some specific conditions (e.g., yes-no recognition) under which investigators should be especially cautious in relying on confidence to infer accuracy. In addition, results point to a general framework for understanding moderating effects on eyewitness metamemory accuracy.

  11. Content Analysis as a Foundation for Programmatic Research in Communication. (United States)

    Slater, Michael D


    Previous arguments that content analyses provide the descriptive foundation for media effects research (McLeod & Reeves, 1980) are extended to include that content analyses can provide a sound and useful foundation for programmatic research by individual communication scientists. I discuss examples from my own work and from that of colleagues in communication and related disciplines. Use of messages sampled and coded in a content analysis in combination with survey data sets or as stimuli in experiments are highlighted. The particular potential for employing larger numbers of randomly sampled messages in experimental designs, and, with use of appropriate statistical methods, being able to generalize to populations of messages, is described.

  12. Methane Content Estimation in DuongHuy Coal Mine (United States)

    Nguyen, Van Thinh; Mijał, Waldemar; Dang, Vu Chi; Nguyen, Thi Tuyet Mai


    Methane hazard has always been considered for underground coal mining as it can lead to methane explosion. In Quang Ninh province, several coal mines such as Mạo Khe coal mine, Khe Cham coal mine, especially Duong Huy mine that have high methane content. Experimental data to examine contents of methane bearing coal seams at different depths are not similar in Duong coal mine. In order to ensure safety, this report has been undertaken to determine a pattern of changing methane contents of coal seams at different exploitation depths in Duong Huy underground coal mine.

  13. Standards-based Content Resources: A Prerequisite for Content Integration and Content Interoperability

    Directory of Open Access Journals (Sweden)

    Christian Galinski


    Full Text Available Objective: to show how standards-based approaches for content standardization, content management, content related services and tools as well as the respective certification systems not only guarantee reliable content integration and content interoperability, but also are of particular benefit to people with special needs in eAccessibility/eInclusion. Method: document MoU/MG/05 N0221 ''Semantic Interoperability and the need for a coherent policy for a framework of distributed, possibly federated repositories for all kinds of content items on a world-wide scale''2, which was adopted in 2005, was a first step towards the formulation of global interoperability requirements for structured content. These requirements -based on advanced terminological principles- were taken up in EU-projects such as IN-SAFETY (INfrastructure and SAFETY and OASIS (Open architecture for Accessible Services Integration and Standardization. Results: Content integration and content interoperability are key concepts in connection with the emergence of state-of-the-art distributed and federated databases/repositories of structured content. Given the fact that linguistic content items are increasingly combined with or embedded in non-linguistic content items (and vice versa, a systemic and generic approach to data modelling and content management has become the order of the day. Fulfilling the requirements of capability for multilinguality and multimodality, based on open standards makes software and database design fit for eAccessibility/eInclusion from the outset. It also makes structured content capable for global content integration and content interoperability, because it enhances its potential for being re-used and re-purposed in totally different eApplications. Such content as well as the methods, tools and services applied can be subject to new kinds of certification schemes which also should be based on standards. Conclusions: Content must be totally reliable in some

  14. Contagious Content: Viral Video Ads Identification of Content Characteristics that Help Online Video Advertisements Go Viral

    Directory of Open Access Journals (Sweden)

    Yentl Knossenburg


    Full Text Available Why do some online video advertisements go viral while others remain unnoticed? What kind of video content keeps the viewer interested and motivated to share? Many companies have realized the need to innovate their marketing strategies and have embraced the newest ways of using technology, as the Internet, to their advantage as in the example of virality. Yet few marketers actually understand how, and academic literature on this topic is still in development. This study investigated which content characteristics distinguish successful from non-successful online viral video advertisements by analyzing 641 cases using Structural Equation Modeling. Results show that Engagement and Surprise are two main content characteristics that significantly increase the chance of online video advertisements to go viral.  

  15. Explicit argumentation instruction to facilitate conceptual understanding and argumentation skills (United States)

    Seda Cetin, Pinar


    Background: Argumentation is accepted by many science educators as a major component of science education. Many studies have investigated students' conceptual understanding and their engagement in argumentative activities. However, studies conducted in the subject of chemistry are very rare. Purpose: The present study aimed to investigate the effects of argumentation-based chemistry lessons on pre-service science teachers' understanding of reaction rate concepts, their quality of argumentation, and their consideration of specific reaction rate concepts in constructing an argument. Moreover, students' perceptions of argumentation lessons were explored. Sample: There were 116 participants (21 male and 95 female), who were pre-service first-grade science teachers from a public university. The participants were recruited from the two intact classes of a General Chemistry II course, both of which were taught by the same instructor. Design and methods: In the present study, non-equivalent control group design was used as a part of quasi-experimental design. The experimental group was taught using explicit argumentation activities, and the control group was instructed using traditional instruction. The data were collected using a reaction rate concept test, a pre-service teachers' survey, and the participants' perceptions of the argumentation lessons questionnaire. For the data analysis, the Wilcoxon Signed Rank Test, the Mann-Whitney U-test and qualitative techniques were used. Results: The results of the study indicated that an argumentation-based intervention caused significantly better acquisition of scientific reaction rate-related concepts and positively impacted the structure and complexity of pre-service teachers' argumentation. Moreover, the majority of the participants reported positive feelings toward argumentation activities. Conclusions: As students are encouraged to state and support their view in the chemistry classroom when studying reaction rate, it was

  16. Understanding medical device regulation. (United States)

    Galgon, Richard E


    The purpose of this article is to provide a structural and functional understanding of the systems used for the regulation of medical devices in the USA and European Union (EU). Safe and effective anesthesia care depends heavily on medical devices, including simple, low risk devices to complex life-supporting and life-sustaining devices. In the USA and EU, the Food and Drug Administration and European Commission, respectively, provide regulatory oversight to ensure medical devices are reasonably safe and effective when used for their intended purposes. Unfortunately, practicing anesthesiologists generally have little or no understanding of how medical devices are regulated, nor do they have sufficient knowledge of available adverse event reporting systems. The US and EU medical device regulatory systems are similar in many ways, but differ in important ways too, which impacts the afforded level of safety and effectiveness assurance. In both systems, medical devices are classified and regulated on a risk basis, which fundamentally differs from drug regulation, where uniform requirements are imposed. Anesthesia providers must gain knowledge of these systems and be active players in both premarket and postmarket activities, particularly with regard to vigilance and adverse event/device failure reporting.

  17. Understanding Callisto's Atmosphere (United States)

    Spencer, John


    We plan to address first-order questions about the nature and origin of the mysterious atmosphere of Callisto, including its composition, longitudinal distribution, formation, and support mechanisms. This investigation is made possible by the remarkable sensitivity of the COS instrument, which has recently detected faint 1304 A and 1356 A O I emission from Callisto's leading / Jupiter-facing quadrant. The emission is probably due to dissociation of O2 molecules in Callisto's atmosphere by photo-electrons, and resonant scattering from an extended atomic O corona. We suspect, from Galileo ionospheric data, that the atmosphere may be much denser, and brighter in emission, on the trailing hemisphere, as expected for a sputter-generated atmosphere, and propose to test the sputter generation hypothesis with 4-orbit COS integrations on the leading and trailing hemispheres. If the trailing side emissions are indeed brighter, the improved SNR there will also allow much improved determination of atmospheric and coronal composition and optical depth. The observations will set the stage for, and aid in planning of, the extensive observations of Callisto's environment planned for the JUICE mission. Because Callisto's atmospheric oxygen emissions are indirectly illuminated by sunlight, which is uniform and quantifiable, it is much easier to understand atmospheric spatial distribution, and thus origin, than on Europa and Ganymede were emissions depend on magnetospheric excitation which is spatially variable and poorly understood. Callisto's atmosphere thus provides a unique chance to better understand the oxygen atmospheres of all the icy Galilean moons.

  18. Understanding Lustre Internals

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Feiyi [ORNL; Oral, H Sarp [ORNL; Shipman, Galen M [ORNL; Drokin, Oleg [ORNL; Wang, Di [ORNL; Huang, He [ORNL


    Lustre was initiated and funded, almost a decade ago, by the U.S. Department of Energy (DoE) Office of Science and National Nuclear Security Administration laboratories to address the need for an open source, highly-scalable, high-performance parallel filesystem on by then present and future supercomputing platforms. Throughout the last decade, it was deployed over numerous medium-to-large-scale supercomputing platforms and clusters, and it performed and met the expectations of the Lustre user community. As it stands at the time of writing this document, according to the Top500 list, 15 of the top 30 supercomputers in the world use Lustre filesystem. This report aims to present a streamlined overview on how Lustre works internally at reasonable details including relevant data structures, APIs, protocols and algorithms involved for Lustre version 1.6 source code base. More importantly, it tries to explain how various components interconnect with each other and function as a system. Portions of this report are based on discussions with Oak Ridge National Laboratory Lustre Center of Excellence team members and portions of it are based on our own understanding of how the code works. We, as the authors team bare all responsibilities for all errors and omissions in this document. We can only hope it helps current and future Lustre users and Lustre code developers as much as it helped us understanding the Lustre source code and its internal workings.

  19. Understanding vented gas explosions

    Energy Technology Data Exchange (ETDEWEB)

    Lautkaski, R. [VTT Energy, Espoo (Finland). Energy Systems


    The report is an introduction to vented gas explosions for nonspecialists, particularly designers of plants for flammable gases and liquids. The phenomena leading to pressure generation in vented gas explosions in empty and congested rooms are reviewed. The four peak model of vented gas explosions is presented with simple methods to predict the values of the individual peaks. Experimental data on the external explosion of dust and gas explosions is discussed. The empirical equation relating the internal and external peak pressures in vented dust explosions is shown to be valid for gas explosion tests in 30 m{sup 3} and 550 m{sup 3} chambers. However, the difficulty of predicting the internal peak pressure in large chambers remains. Methods of explosion relief panel design and principles of vent and equipment layout to reduce explosion overpressures are reviewed. (orig.) 65 refs.

  20. Experimental Affinities in Music


    de Assis, Paulo


    Experimental Affinities in Music brings together diverse artistic, musicological, historical, and philosophical essays, enhancing a broad discourse on artistic experimentation, and exploring various experimental attitudes in music composed between the thirteenth and twentieth centuries. The golden thread running through the different chapters is the quest for inherently experimental musical practices, a quest pursued from interrogating, descriptive, or challenging perspectives, and always...

  1. The Challenges in Developing E-Content

    Directory of Open Access Journals (Sweden)

    Jowati Juhary


    Full Text Available Malaysia is considered an active key player in information communication technologies (ICTs especially in education. In fact, in the National Higher Education Strategic Plan, one of the Critical Agenda Projects (CAPs of the Minister of Higher Education is e-learning. It goes without saying that all higher learning providers in Malaysia must be prepared to provide state-of-the-art facilities for the students. One critical aspect of e-learning is the quality and quantity of the content, or what will be referred by many scholars as e-content. This paper attempts to identify the challenges of content development for e-learning practice at the National Defence University of Malaysia (NDUM. It is crucial to investigate this issue since the university just purchased its Learning Management System (LMS. It is expected that resistance will be present as the academics at the defence university is a mixture of junior and senior lecturers, as well as civilian and military lecturers; and some of these academics have been teaching without the assistance of e-learning. In so doing, the methodology of this paper will mainly be content analysis of various reports, governmental documents, as well as semi-structured interviews with lecturers at the NDUM. As this paper acts as a preliminary investigation into the issue of e-content at the university, only seven lecturers were interviewed. Initial findings suggest that there are basically five challenges of developing e-content at the NDUM. These include the lack of ICT and e-learning policy that can provide guidelines to academics; the uncertainty of ownership for e-learning initiatives; the lack of understanding of the roles of e-learning; the lack of awareness on e-learning; and the difficulties to develop military based content due to confidentiality issues. Two possible solutions for these challenges are also examined which take into consideration the urgent need to set up an e-Learning Unit and to provide

  2. Contagious Content: Viral Video Ads Identification of Content Characteristics that Help Online Video Advertisements Go Viral


    Yentl Knossenburg; Roberto Nogueira; Paula Chimenti


    Why do some online video advertisements go viral while others remain unnoticed? What kind of video content keeps the viewer interested and motivated to share? Many companies have realized the need to innovate their marketing strategies and have embraced the newest ways of using technology, as the Internet, to their advantage as in the example of virality. Yet few marketers actually understand how, and academic literature on this topic is still in development. This study investigated which con...

  3. Understanding Editing Behaviors in Multilingual Wikipedia. (United States)

    Kim, Suin; Park, Sungjoon; Hale, Scott A; Kim, Sooyoung; Byun, Jeongmin; Oh, Alice H


    Multilingualism is common offline, but we have a more limited understanding of the ways multilingualism is displayed online and the roles that multilinguals play in the spread of content between speakers of different languages. We take a computational approach to studying multilingualism using one of the largest user-generated content platforms, Wikipedia. We study multilingualism by collecting and analyzing a large dataset of the content written by multilingual editors of the English, German, and Spanish editions of Wikipedia. This dataset contains over two million paragraphs edited by over 15,000 multilingual users from July 8 to August 9, 2013. We analyze these multilingual editors in terms of their engagement, interests, and language proficiency in their primary and non-primary (secondary) languages and find that the English edition of Wikipedia displays different dynamics from the Spanish and German editions. Users primarily editing the Spanish and German editions make more complex edits than users who edit these editions as a second language. In contrast, users editing the English edition as a second language make edits that are just as complex as the edits by users who primarily edit the English edition. In this way, English serves a special role bringing together content written by multilinguals from many language editions. Nonetheless, language remains a formidable hurdle to the spread of content: we find evidence for a complexity barrier whereby editors are less likely to edit complex content in a second language. In addition, we find that multilinguals are less engaged and show lower levels of language proficiency in their second languages. We also examine the topical interests of multilingual editors and find that there is no significant difference between primary and non-primary editors in each language.

  4. Understanding Editing Behaviors in Multilingual Wikipedia.

    Directory of Open Access Journals (Sweden)

    Suin Kim

    Full Text Available Multilingualism is common offline, but we have a more limited understanding of the ways multilingualism is displayed online and the roles that multilinguals play in the spread of content between speakers of different languages. We take a computational approach to studying multilingualism using one of the largest user-generated content platforms, Wikipedia. We study multilingualism by collecting and analyzing a large dataset of the content written by multilingual editors of the English, German, and Spanish editions of Wikipedia. This dataset contains over two million paragraphs edited by over 15,000 multilingual users from July 8 to August 9, 2013. We analyze these multilingual editors in terms of their engagement, interests, and language proficiency in their primary and non-primary (secondary languages and find that the English edition of Wikipedia displays different dynamics from the Spanish and German editions. Users primarily editing the Spanish and German editions make more complex edits than users who edit these editions as a second language. In contrast, users editing the English edition as a second language make edits that are just as complex as the edits by users who primarily edit the English edition. In this way, English serves a special role bringing together content written by multilinguals from many language editions. Nonetheless, language remains a formidable hurdle to the spread of content: we find evidence for a complexity barrier whereby editors are less likely to edit complex content in a second language. In addition, we find that multilinguals are less engaged and show lower levels of language proficiency in their second languages. We also examine the topical interests of multilingual editors and find that there is no significant difference between primary and non-primary editors in each language.

  5. Experimental Engineering: Articulating and Valuing Design Experimentation

    DEFF Research Database (Denmark)

    Vallgårda, Anna; Grönvall, Erik; Fritsch, Jonas


    In this paper we propose Experimental Engineering as a way to articulate open- ended technological experiments as a legitimate design research practice. Experimental Engineering introduces a move away from an outcome or result driven design process towards an interest in existing technologies...

  6. Experimental and Quasi-Experimental Design. (United States)

    Cottrell, Edward B.

    With an emphasis on the problems of control of extraneous variables and threats to internal and external validity, the arrangement or design of experiments is discussed. The purpose of experimentation in an educational institution, and the principles governing true experimentation (randomization, replication, and control) are presented, as are…

  7. Webizing mobile augmented reality content (United States)

    Ahn, Sangchul; Ko, Heedong; Yoo, Byounghyun


    This paper presents a content structure for building mobile augmented reality (AR) applications in HTML5 to achieve a clean separation of the mobile AR content and the application logic for scaling as on the Web. We propose that the content structure contains the physical world as well as virtual assets for mobile AR applications as document object model (DOM) elements and that their behaviour and user interactions are controlled through DOM events by representing objects and places with a uniform resource identifier. Our content structure enables mobile AR applications to be seamlessly developed as normal HTML documents under the current Web eco-system.

  8. Understanding empathy and related phenomena. (United States)

    Shamasundar, C


    Over a period of time, the author arrived at a few tentative postulates concerning empathy and related processes based on some of his experiences and observations. The central theme of these postulates is, firstly, that interpersonal interaction is an interaction of the personal-space fields. Secondly, empathy, therapeutic benefit, and the professional stress are all related to the same process of interpersonal interaction. This interaction takes place as an enmeshment of personal spaces of the interacting individuals, and involves transfer of a wide range of information in the affective, cognitive, and other areas. This is because the personal spaces have fieldlike qualities analogous to what Kurt Lewin described. Thus, such phenomena as empathy, therapeutic benefit, professional stress are all consequences of the same process. It is possible to substantiate these postulates by diverse evidences in the published literature. The natural consequences of such an interpersonal interaction are empathic understanding, transfer of mood states (like hope, distress or expectancy), affective states (like anxiety, sadness, anger or hostility), ideas, images and even attitudes and values, etc. This phenomenon of transfer can explain such processes as therapeutic benefit in individual and group settings, professional stress, shared delusions, and even experimenter bias. Whether one becomes aware of such transferred information or not depends upon the intent and sensitivity of the participants.

  9. Understanding engineering mathematics

    CERN Document Server

    Cox, Bill


    * Unique interactive style enables students to diagnose their strengths and weaknesses and focus their efforts where needed* Ideal for self-study and tutorial work, building from an initially supportive approach to the development of independent learning skills * Free website includes solutions to all exercises, additional topics and applications, guide to learning mathematics, and practice materialStudents today enter engineering courses with a wide range of mathematical skills, due to the many different pre-university qualifications studied. Bill Cox''s aim is for students to gain a thorough understanding of the maths they are studying, by first strengthening their background in the essentials of each topic. His approach allows a unique self-paced study style, in which students Review their strengths and weaknesses through self-administered diagnostic tests, then focus on Revision where they need it, to finally Reinforce the skills required.The book is structured around a highly successful ''transition'' ma...

  10. From understanding to participation

    DEFF Research Database (Denmark)

    Raudaskoski, Pirkko Liisa


    The paper presents some methodological considerations around the topic of the AFinLA 2012 Autumn Symposium: Multimodal discourses of participation. The aim is to shed theoretical and analytical light on embodied participation in material settings. The research is placed in a relational perspective...... in which entities (for example, the world, culture, society, organization and identities) emerge through entangled, layered practices in concrete circumstances. Understanding is not treated as a philosophical puzzle or as a purely linguistic phenomenon. Rather, it is conceptualized as an embodied......, multimodal process in which language together with bodily senses (vision, hearing, touch, smell and taste) and a sense of place contribute to a phenomenon being recognized (as shared). Participation can result in inclusion or exclusion, a claim which is discussed with the help of a pilot study from...

  11. Understanding land administration systems

    DEFF Research Database (Denmark)

    P. Williamson, Ian; Enemark, Stig; Wallace, Judy


    This paper introduces basic land administration theory and highlights four key concepts that are fundamental to understanding modern land administration systems - firstly the land management paradigm and its influence on the land administration framework, secondly the role that the cadastre plays...... in contributing to sustainable development, thirdly the changing nature of ownership and the role of land markets, and lastly a land management vision that promotes land administration in support of sustainable development and spatial enablement of society. We present here the first part of the paper. The second...... part focuses on the changing  role of ownership and the role of land markets, and a land management vision will be published in November issue of Coordinates. Udgivelsesdato: Oktober...

  12. Understanding medical symptoms

    DEFF Research Database (Denmark)

    Malterud, Kirsti; Guassora, Ann Dorrit Kristiane; Graungaard, Anette Hauskov


    perspectives deal with how symptom perception occurs when any kind of altered balance brings forward a bodily attention. Corporeality is brought to explicit awareness and perceived as sensations. Jesper Hoffmeyer’s biosemiotic perspectives provide access to how signs are interpreted to attribute meaning......The aim of this article is to present a conceptual review and analysis of symptom understanding. Subjective bodily sensations occur abundantly in the normal population and dialogues about symptoms take place in a broad range of contexts, not only in the doctor’s office. Our review of symptom...... is a social and relational phenomenon of containment, and regulating the situation where the symptoms originate implies adjusting containment. Discourse analysis, as presented by Jonathan Potter and Margaret Wetherell, provides a tool to notice the subtle ways in which language orders perceptions and how...

  13. Understanding philosophical animal

    Directory of Open Access Journals (Sweden)

    Popović Una


    Full Text Available In this paper, inspired by the Predrag Krstić's book Philosophical Animal author is trying to find hers way through a broad and complex web of philosophies and roles that different animals play in them. The main question is how to understand philosophy itself in a present day context, which philosophy is supposed to think and rethink through. Animals as presented in concepts, more precisely philosophical contexts, open one interesting and innovative way to deal with this question, balancing between tradition of philosophy and its presence, structure of philosophical arguments and questioning of language of philosophy, abstract and individual. In this frame philosopher as the true philosophical animal is revealed as the main symbol that requires analysis in his philosophical strategies.

  14. Towards better process understanding

    DEFF Research Database (Denmark)

    Matero, Sanni Elina; van der Berg, Franciscus Winfried J; Poutiainen, Sami


    The manufacturing of tablets involves many unit operations that possess multivariate and complex characteristics. The interactions between the material characteristics and process related variation are presently not comprehensively analyzed due to univariate detection methods. As a consequence......, current best practice to control a typical process is to not allow process-related factors to vary i.e. lock the production parameters. The problem related to the lack of sufficient process understanding is still there: the variation within process and material properties is an intrinsic feature...... and cannot be compensated for with constant process parameters. Instead, a more comprehensive approach based on the use of multivariate tools for investigating processes should be applied. In the pharmaceutical field these methods are referred to as Process Analytical Technology (PAT) tools that aim...

  15. Understanding person perception. (United States)

    Young, Andrew W; Bruce, Vicki


    Bruce and Young's (1986) theoretical framework was actually a synthesis of ideas contributed by several people. Some of its insights have stood the test of time - especially the importance of using converging evidence from as wide a range of methods of enquiry as possible, and an emphasis on understanding the demands that are made by particular face perception tasks. But there were also areas where Bruce and Young failed to obey their own edicts (emotion recognition), and some topics they simply omitted (gaze perception). We discuss these, and then look at how the field has been transformed by computing developments, finishing with a few thoughts about where things may go over the next few (25?) years. ©2011 The British Psychological Society.

  16. Understanding Defense Mechanisms. (United States)

    Cramer, Phebe


    Understanding defense mechanisms is an important part of psychotherapy. In this article, we trace the history of the concept of defense, from its origin with Freud to current views. The issue of defense as an unconscious mechanism is examined. The question of whether defenses are pathological, as well as their relation to pathology, is discussed. The effect of psychotherapy on the use of defenses, and their relation to a therapeutic alliance is explored. A series of empirical research studies that demonstrate the functioning of defense mechanisms and that support the theory is presented. Research also shows that as part of normal development, different defenses emerge at different developmental periods, and that gender differences in defense use occur.

  17. Understanding social motor coordination. (United States)

    Schmidt, R C; Fitzpatrick, Paula; Caron, Robert; Mergeche, Joanna


    Recently there has been much interest in social coordination of motor movements, or as it is referred to by some researchers, joint action. This paper reviews the cognitive perspective's common coding/mirror neuron theory of joint action, describes some of its limitations and then presents the behavioral dynamics perspective as an alternative way of understanding social motor coordination. In particular, behavioral dynamics' ability to explain the temporal coordination of interacting individuals is detailed. Two experiments are then described that demonstrate how dynamical processes of synchronization are apparent in the coordination underlying everyday joint actions such as martial art exercises, hand-clapping games, and conversations. The import of this evidence is that emergent dynamic patterns such as synchronization are the behavioral order that any neural substrate supporting joint action (e.g., mirror systems) would have to sustain. Copyright © 2010 Elsevier B.V. All rights reserved.

  18. Understanding traditional African healing. (United States)

    Mokgobi, M G


    Traditional African healing has been in existence for many centuries yet many people still seem not to understand how it relates to God and religion/spirituality. Some people seem to believe that traditional healers worship the ancestors and not God. It is therefore the aim of this paper to clarify this relationship by discussing a chain of communication between the worshipers and the Almighty God. Other aspects of traditional healing namely types of traditional healers, training of traditional healers as well as the role of traditional healers in their communities are discussed. In conclusion, the services of traditional healers go far beyond the uses of herbs for physical illnesses. Traditional healers serve many roles which include but not limited to custodians of the traditional African religion and customs, educators about culture, counselors, social workers and psychologists.

  19. Pedagogical Content Knowledge and the Gas Laws: A Multiple Case Study (United States)

    Sande, Mary Elizabeth


    Pedagogical content knowledge (PCK) has been described as an assemblage of the most powerful analogies, demonstrations, examples and illustrations that make content knowledge understandable to students, together with an understanding of the preconceptions and alternate conceptions that students bring with them to the classroom (Shulman, 1986). In…

  20. Teaching Concepts of Natural Sciences to Foreigners through Content-Based Instruction: The Adjunct Model (United States)

    Satilmis, Yilmaz; Yakup, Doganay; Selim, Guvercin; Aybarsha, Islam


    This study investigates three models of content-based instruction in teaching concepts and terms of natural sciences in order to increase the efficiency of teaching these kinds of concepts in realization and to prove that the content-based instruction is a teaching strategy that helps students understand concepts of natural sciences. Content-based…

  1. Influence of Fat Content on Chocolate Rheology (United States)

    Gabriele, D.; Migliori, M.; Baldino, N.; de Cindio, B.


    Molten chocolate is a suspension having properties strongly affected by particle characteristics including not only the dispersed particles but also the fat crystals formed during chocolate cooling and solidification. Even though chocolate rheology is extensively studied, mainly viscosity at high temperature was determined and no information on amount and type of fat crystals can be detected in these conditions. However chocolate texture and stability is strongly affected by the presence of specific crystals. In this work a different approach, based on creep test, was proposed to characterize chocolate samples at typical process temperatures (approximately 30 °C). The analysis of compliance, as time function, at short times enable to evaluate a material "elasticity" related to the solid-like behavior of the material and given by the differential area between the Newtonian and the experimental compliance. Moreover a specific time dependent elasticity was defined as the ratio between the differential area, in a time range, and total area. Chocolate samples having a different fat content were prepared and they were conditioned directly on rheometer plate by applying two different controlled cooling rate; therefore creep were performed by applying a low stress to ensure material linear behavior. Experimental data were analyzed by the proposed method and specific elasticity was related to single crystal properties. It was found that fat crystal amount and properties depend in different way on fat content and cooling rate; moreover creep proved to be able to detect even small differences among tested samples.

  2. Developing test for experimental study: the effectiveness of hedwig strategy in english education department universitas brawijaya

    Directory of Open Access Journals (Sweden)

    Devinta Puspita Ratri


    Having a big number of students in content subject of a language class is a challenge for teacher since it is quite difficult to accommodate students’ critical thinking and active participation at the same time. Therefore, Hedwig strategy is aimed to give room for students to explore themselves and get involved in the materials delivered in the class. Furthermore, by having group and regroup to deliver message in Hedwig strategy, students are forced to be active participated in classroom activities. The idea of Hedwig strategy is inspired by Jigsaw and Think-Pair-Share which have existed before. To know whether Hedwig strategy is effectively applied in content subject in large language class, it is proposed to do quasi experimental study with one class as an experimental group and one class as a control group. The experimental group is treated by using Hedwig strategy. Prior to the experimental study, it is performed research and development to develop the test for pre-test and post-test. For that reason, the research problem is what test is valid and reliable for an experimental study on the effectiveness of Hedwig strategy for the 4th semester students in Language Teaching Methodology class in English Education Department Universitas Brawijaya. This research reports half of the whole plan where the researchers developed test for pre-test and posttest to measure students’ improvement in understanding Language Teaching Methodology. In short, the test developed in this study will be used to carry out experimental study as pre-test and post-test

  3. Motor responses to experimental Achilles tendon pain

    DEFF Research Database (Denmark)

    Henriksen, Marius; Aaboe, Jens; Graven-Nielsen, Thomas


    of the exercise are affected by Achilles tendon pain. Objective The authors aimed to determine the effects of experimental Achilles tendon pain on motor function during one-legged weight bearing ankle plantar and dorsal flexion exercises. Methods In a crossover study, with 16 healthy subjects tested on two...... before, during and after either experimental Achilles tendon pain or a non-painful control condition. Pain was induced by intratendinous injections of hypertonic saline with isotonic saline injections as control. Joint kinematics, ground reaction force frequency contents and average EMG amplitudes were...... calculated. Results Compared with the control condition experimental Achilles tendon pain reduced the EMG activity in agonistic, synergistic and antagonistic muscles, and increased the ground reaction force frequency content around 10 Hz, during both eccentric and concentric movement phases. Conclusions...

  4. Understanding Engineering Ethics

    Directory of Open Access Journals (Sweden)

    Abdi O. Shuriye


    Full Text Available Engineering ethics aims to enhance engineer’s ability to confront moral issues raised by engineering activities. It covers engineering as social experimentation, the engineer’s responsibility for safety, and the rights of engineers. What constitutes engineering ethics is the underlining question of this research. Hence, the objective of the research is to systematically provide answers to the aforementioned question. The research also studies the scope and the origin of the subject matter. At the same time, the research highlights the significance of the subject from diverse perspectives; including Western and Islamic perspectives. ABSTRAK: Etika kejuruteraan bertujuan meningkatkan keupayaan juruera menghadapi isu-isu moralyang timbul dari aktiviti-aktiviti kejuruteraan. Ia merangkumi kejuruteraan sebagai eksperimentasi sosial, tanggungjawab jurutera terhadap keselamatan dan hak-hak jurutera. Persoalan utama penyelidikan ini adalah apa yang merangkumi etika kejuruteraan. Penyelidikan ini juga mengkaji skop dan asal usul etika kejuruteraan. Kajian ini turut membincangkan subjek kajian dari pelbagai perspektif, Barat dan Islam.KEYWORDS: engineering ethics; engineer; akhlaq; values; confidentiality; corruption; conflict of interest; whistle-blowing

  5. Verbal communication of semantic content in products

    DEFF Research Database (Denmark)

    Lenau, Torben Anker; Boelskifte, Per


    participants have a good mutual understanding of these qualities and a vocabulary to match, it is more likely that the resulting products will reflect the intentions and requirements better. Research carried out so far includes 3 investigations with a combination of questionnaires and an experiment where...... product search was carried out based on verbal communication alone. Preliminary results indicate that there exists a mutual understanding of many of the terms describing the qualities and properties and that good verbal communication of sensory and perceived product qualities are possible. However...... a number of the selected terms seem to have several interpretations causing ambiguous information. The work also suggests that more emphasis is needed in design education on training precise verbal communication concerning semantic contents in products....

  6. Cancer Patients' Informational Needs: Qualitative Content Analysis. (United States)

    Heidari, Haydeh; Mardani-Hamooleh, Marjan


    Understanding the informational needs of cancer patients is a requirement to plan any educative care program for them. The aim of this study was to identify Iranian cancer patients' perceptions of informational needs. The study took a qualitative approach. Semi-structured interviews were held with 25 cancer patients in two teaching hospitals in Iran. Transcripts of the interviews underwent conventional content analysis, and categories were extracted. The results came under two main categories: disease-related informational needs and information needs related to daily life. Disease-related informational needs had two subcategories: obtaining information about the nature of disease and obtaining information about disease prognosis. Information needs related to daily life also had two subcategories: obtaining information about healthy lifestyle and obtaining information about regular activities of daily life. The findings provide deep understanding of cancer patients' informational needs in Iran.

  7. Automatic Content Creation for Games to Train Students Distinguishing Similar Chinese Characters (United States)

    Lai, Kwong-Hung; Leung, Howard; Tang, Jeff K. T.

    In learning Chinese, many students often have the problem of mixing up similar characters. This can cause misunderstanding and miscommunication in daily life. It is thus important for students learning the Chinese language to be able to distinguish similar characters and understand their proper usage. In this paper, we propose a game style framework in which the game content in identifying similar Chinese characters in idioms and words is created automatically. Our prior work on analyzing students’ Chinese handwriting can be applied in the similarity measure of Chinese characters. We extend this work by adding the component of radical extraction to speed up the search process. Experimental results show that the proposed method is more accurate and faster in finding more similar Chinese characters compared with the baseline method without considering the radical information.

  8. Tools for Understanding Identity

    Energy Technology Data Exchange (ETDEWEB)

    Creese, Sadie; Gibson-Robinson, Thomas; Goldsmith, Michael; Hodges, Duncan; Kim, Dee DH; Love, Oriana J.; Nurse, Jason R.; Pike, William A.; Scholtz, Jean


    Identity attribution and enrichment is critical to many aspects of law-enforcement and intelligence gathering; this identity typically spans a number of domains in the natural-world such as biographic information (factual information – e.g. names, addresses), biometric information (e.g. fingerprints) and psychological information. In addition to these natural-world projections of identity, identity elements are projected in the cyber-world. Conversely, undesirable elements may use similar techniques to target individuals for spear-phishing attacks (or worse), and potential targets or their organizations may want to determine how to minimize the attack surface exposed. Our research has been exploring the construction of a mathematical model for identity that supports such holistic identities. The model captures the ways in which an identity is constructed through a combination of data elements (e.g. a username on a forum, an address, a telephone number). Some of these elements may allow new characteristics to be inferred, hence enriching the holistic view of the identity. An example use-case would be the inference of real names from usernames, the ‘path’ created by inferring new elements of identity is highlighted in the ‘critical information’ panel. Individual attribution exercises can be understood as paths through a number of elements. Intuitively the entire realizable ‘capability’ can be modeled as a directed graph, where the elements are nodes and the inferences are represented by links connecting one or more antecedents with a conclusion. The model can be operationalized with two levels of tool support described in this paper, the first is a working prototype, the second is expected to reach prototype by July 2013: Understanding the Model The tool allows a user to easily determine, given a particular set of inferences and attributes, which elements or inferences are of most value to an investigator (or an attacker). The tool is also able to take

  9. Statistical Model for Content Extraction

    DEFF Research Database (Denmark)

    Qureshi, Pir Abdul Rasool; Memon, Nasrullah


    We present a statistical model for content extraction from HTML documents. The model operates on Document Object Model (DOM) tree of the corresponding HTML document. It evaluates each tree node and associated statistical features to predict significance of the node towards overall content of the ...... also describe the significance of the model in the domain of counterterrorism and open source intelligence....

  10. Uranium content of Philippine coals

    International Nuclear Information System (INIS)

    De la Rosa, A.M.; Sombrito, E.Z.; Nuguid, Z.S.; Bulos, A.M.; Bucoy, B.M.; De la Cruz, M.


    Uranium content of coal samples from seven areas in the Philippines, i.e. Cebu, Semirara, Bislig, Albay, Samar, Malangas and Polilio Is. was found to contain trace quantities of uranium. The mean value of 0.401 ppm U is lower than reported mean uranium contents for coal from other countries. (ELC)

  11. Content-based management service for medical videos. (United States)

    Mendi, Engin; Bayrak, Coskun; Cecen, Songul; Ermisoglu, Emre


    Development of health information technology has had a dramatic impact to improve the efficiency and quality of medical care. Developing interoperable health information systems for healthcare providers has the potential to improve the quality and equitability of patient-centered healthcare. In this article, we describe an automated content-based medical video analysis and management service that provides convenience and ease in accessing the relevant medical video content without sequential scanning. The system facilitates effective temporal video segmentation and content-based visual information retrieval that enable a more reliable understanding of medical video content. The system is implemented as a Web- and mobile-based service and has the potential to offer a knowledge-sharing platform for the purpose of efficient medical video content access.

  12. Improving the quantum mechanics content knowledge and pedagogical content knowledge of physics graduate students (United States)

    Marshman, Emily Megan

    Many physics graduate students face the unique challenge of being both students and teachers concurrently. To succeed in these roles, they must develop both physics content knowledge and pedagogical content knowledge. My research focuses on improving both the content knowledge and pedagogical content knowledge of first year graduate students. To improve their content knowledge, I have focused on improving graduate students' conceptual understanding of quantum mechanics covered in upper-level undergraduate courses since our earlier investigations suggest that many graduate students struggle in developing a conceptual understanding of quantum mechanics. Learning tools, such as the Quantum Interactive Learning Tutorials (QuILTs) that I have developed, have been successful in helping graduate students improve their understanding of Dirac notation and single photon behavior in the context of a Mach-Zehnder Interferometer. In addition, I have been involved in enhancing our semester long course professional development course for teaching assistants (TAs) by including research-based activities. In particular, I have been researching the implications of graduate TAs' reflections on the connections between their grading practices and student learning, i.e., the development of introductory physics students' content knowledge and problem-solving, reasoning, and metacognitive skills. This research involves having graduate students grade sample student solutions to introductory physics problems. Afterward, the graduate TAs discuss with each other the pros and cons of different grading rubrics on student learning and formulate a joint grading rubric to grade the problem. The graduate TAs are individually asked to reformulate a rubric and grade problems using the rubric several months after the group activity to assess the impact of the intervention on graduate TAs. In addition to the intervention focusing on grading sample student solutions, graduate TAs are also asked to answer

  13. Content Validation of a Catalog of Exercises for Judo. (United States)

    Pedrosa, Gustavo F; Soares, Ytalo M; Gonçalves, Reginaldo; Couto, Bruno P; Dias, Ronaldo A; Costa, Varley T; Kalina, Roman M; Szmuchrowski, Leszek A


    This study aimed to assess the content validity of a catalog of 76 judo exercises. Two groups of raters comprising 16 judo experts evaluated the following content validity indicators: Clarity of Language, Practical Pertinence, Theoretical Relevance, and the Dimension of each exercise. The results confirmed the content validity of the judo training catalog with indicators showing scores greater than 0.80. These findings suggest that all 76 judo exercises are pertinent, representative of judo training and understandable for judo coaches. Thus, this catalog of judo exercises may help judo coaches in the selection and recording of exercises. © The Author(s) 2016.

  14. Moisture content measurement in paddy (United States)

    Klomklao, P.; Kuntinugunetanon, S.; Wongkokua, W.


    Moisture content is an important quantity for agriculture product, especially in paddy. In principle, the moisture content can be measured by a gravimetric method which is a direct method. However, the gravimetric method is time-consuming. There are indirect methods such as resistance and capacitance methods. In this work, we developed an indirect method based on a 555 integrated circuit timer. The moisture content sensor was capacitive parallel plates using the dielectric constant property of the moisture. The instrument generated the output frequency that depended on the capacitance of the sensor. We fitted a linear relation between periods and moisture contents. The measurement results have a standard uncertainty of 1.23 % of the moisture content in the range of 14 % to 20 %.

  15. Evolution of broadcast content distribution

    CERN Document Server

    Beutler, Roland


    This book discusses opportunities for broadcasters that arise with the advent of broadband networks, both fixed and mobile. It discusses how the traditional way of distributing audio-visual content over broadcasting networks has been complemented by the usage of broadband networks. The author shows how this also gives the possibility to offer new types of interactive or so-called nonlinear services. The book illustrates how change in distribution technology is accelerating the need for broadcasters around the world to adapt their content distribution strategy and how it will impact the portfolios of content they offer. Outlines the shift in broadcast content distribution paradigms and related strategic issues Provides an overview of the new broadcasting ecosystem encompassing new types of content, user habits, expectations, and devices Discusses complementary usage of different distribution technologies and platforms.

  16. Relation between moisture content of fine fuels and relative humidity. (United States)

    Harold K. Steen


    Measurements indicate a relation between diurnal curves of relative humidity and moisture content of some important fuels of Oregon and Washington. Some of these measurements were made in early years of forest fire research in this region. The data in this note were collected at intervals throughout 4 days (in September 1938) at the Wind River Experimental Forest near...

  17. Evaluation of bisphenol A content in food from lacquered cans ...

    African Journals Online (AJOL)

    This study describes the migration of bisphenol A from the cans to the food content through experimental tests using internal lacquered cans full of distilled water. Bisphenol A concentrations ranged between 3 and 320 µg.L-1 and increased with the increment of the storage duration, the temperature of storage and the ...

  18. Chlorophyll meter reading and total nitrogen content applied as ...

    African Journals Online (AJOL)

    The present study was aimed to assess the relationship between the reading of the chlorophyll meter and the total nitrogen (N) content in the leaf in different parts of the crambe plant, depending on the doses of nitrogen applied to the canopy. Randomized block design in a split plot experimental design was used. The plots ...

  19. Relationship between soil contents and plasma levels of selenium ...

    African Journals Online (AJOL)

    The soil contents of trace elements selenium, chromium and manganese were measured to determine their impact on the plasma levels of 160 healthy adult Nigerians in five different experimental locations in Cross River and Akwa Ibom States, South - South Nigeria. The mean (±SD) soil selenium, chromium and ...

  20. Towards understanding oral health. (United States)

    Zaura, Egija; ten Cate, Jacob M


    During the last century, dental research has focused on unraveling the mechanisms behind various oral pathologies, while oral health was typically described as the mere absence of oral diseases. The term 'oral microbial homeostasis' is used to describe the capacity of the oral ecosystem to maintain microbial community stability in health. However, the oral ecosystem itself is not stable: throughout life an individual undergoes multiple physiological changes while progressing through infancy, childhood, adolescence, adulthood and old age. Recent discussions on the definition of general health have led to the proposal that health is the ability of the individual to adapt to physiological changes, a condition known as allostasis. In this paper the allostasis principle is applied to the oral ecosystem. The multidimensionality of the host factors contributing to allostasis in the oral cavity is illustrated with an example on changes occurring in puberty. The complex phenomenon of oral health and the processes that prevent the ecosystem from collapsing during allostatic changes in the entire body are far from being understood. As yet individual components (e.g. hard tissues, microbiome, saliva, host response) have been investigated, while only by consolidating these and assessing their multidimensional interactions should we be able to obtain a comprehensive understanding of the ecosystem, which in turn could serve to develop rational schemes to maintain health. Adapting such a 'system approach' comes with major practical challenges for the entire research field and will require vast resources and large-scale multidisciplinary collaborations. 2015 S. Karger AG, Basel