Sample records for under-studied realms identified

  1. Identifying risks in the realm of enterprise risk management. (United States)

    Carroll, Roberta


    An enterprise risk management (ERM) discipline is comprehensive and organization-wide. The effectiveness of ERM is governed in part by the strength and breadth of its practices and processes. An essential element in decision making is a thorough process by which organizational risks and value opportunities can be identified. This article will offer identification techniques that go beyond those used in traditional risk management programs and demonstrate how these techniques can be used to identify risks and opportunity in the ERM environment. © 2016 American Society for Healthcare Risk Management of the American Hospital Association.

  2. Landscape narratives: crossing realms

    Directory of Open Access Journals (Sweden)

    Matthew Potteiger


    Full Text Available Landscape narratives are produced across three related realms: 1. the story 2. the context/intertext and 3. the discourse. The story realm is an analysable system of meaning created by the structuring elements within the world of the story. The contextual or intertextual realm describes the role of individual readers and communities in the production of narratives. The third realm of discourse attends to whose story is told, what purposes it serves and what ideologies inhere in the telling. We apply this framework to interpreting the narrative construction of one place, the Crosby Arboretum in Mississippi. To link the practices of making landscapes to narrative practices requires an expanded notion of text, of the role of readers in producing meaning, as well as recognition of landscape as a spatial narrative shaped by ongoing processes and multiple authors. Design practice derived from understanding these conditions forms 'open narratives', as opposed to the current trend for highly scripted and controlled narratives.

  3. Realm of Matrices

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 20; Issue 2. Realm of Matrices: Exponential and Logarithm Functions. Debapriya Biswas. General Article Volume 20 Issue 2 February 2015 pp 136-150. Fulltext. Click here to view fulltext PDF. Permanent link:

  4. Realm of Matrices

    Indian Academy of Sciences (India)

    IAS Admin

    Lie algebras and their representation theory, harmonic analysis and complex analysis, in particular, Clifford analysis. She is interested in teaching also and enjoys discussing her research interests with others. In this article, we discuss the exponential and the logarithmic functions in the realm of matrices. These notions are ...

  5. Limno-terrestrial Tardigrada of the Nearctic Realm

    Directory of Open Access Journals (Sweden)

    Juliana G. HINTON


    Full Text Available We examined all available records of limno-terrestrial tardigrade distribution in the Nearctic realm (Greenland, Canada, Alaska, the continental United States of America, and northern Mexico, both to compare this fauna with other realms and to investigate distribution within North America. We included only those records in which tardigrades had been identified to species. Of 204 Nearctic limno-terrestrial tardigrade species, 38 were cosmopolitan, while 55 were unique to the Nearctic realm. The Nearctic tardigrade fauna is most similar to the Palearctic, with 135 species in common, 39 of which have not been reported elsewhere. The Nearctic realm shares 82 species with the Neotropical realm, only 10 which are not also Palearctic. These data are consistent with the geological history of the three realms, and indicate a distinction between Laurasian and Gondwanan tardigrade faunas. Although little is known about limno-terrestrial tardigrade distribution in much of North America, there are several excellent regional or local surveys. Many species are distributed widely throughout the continent, but 30.0% of Nearctic species have been reported from a single site. Cluster analysis of the fauna of 11 Nearctic regions shows that the Arctic and sub-Arctic fauna constitute a regional fauna distinct from the rest of the continent. Ecological analysis is hampered by inconsistent reporting of tardigrade substrate, though available data suggest little substrate specificity in terrestrial tardigrades. Most species are found in both mosses and lichens. Many are also present in soil and leaf litter, but few are found only in these substrates.

  6. Ectoparasites--the underestimated realm. (United States)

    Heukelbach, Jörg; Feldmeier, Hermann


    Ectoparasitoses (infestations with parasites that live on or in the skin) can cause considerable morbidity. Whereas pediculosis and scabies are ubiquitous, cutaneous larva migrans and tungiasis (sand-flea disease) occur mainly in hot climates. The prevalence of ectoparasitoses in the general population is usually low, but can be high in vulnerable groups. Scientific knowledge on how to deal best with parasitic skin diseases in different settings is scanty, and evidence-based measures for control are not available. For head lice and scabies the situation is daunting, because resistance of Pediculus humanus capitis and Sarcoptes scabiei to insecticides is spreading and unpredictable. J Hunter and S Barker reported different patterns of resistance in schoolchildren in Brisbane, Australia: full resistance to malathion, permethrin, and pyrethrum in two schools, whereas head lice were susceptible to malathion and, to a lesser extent, to pyrethrums in three other schools (Parasitol Res 2003; 90: 476-78). K Yoon and colleagues found different resistance patterns in the USA and Ecuador (Arch Dermatol 2003; 139: 994-1000). Head lice from Florida were less susceptible to permethrin than those from Texas, and parasites from Ecuador were susceptible to both insecticides tested. WHERE NEXT? The occurrence of resistant pediculosis and scabies is expected to increase numerically and geographically. Clinicoepidemiological studies are urgently needed to identify the factors which govern the emergence and spread of strains of P humanus capitis and S scabiei that are resistant to insecticide or acaricide. Oral treatment with ivermectin could substitute for topically applied compounds, particularly in resource-poor communities where polyparasitism is common. A better understanding of local epidemiology is required to develop control measures. This knowledge has to be applied in combination with environmental sanitation, health education, and culturally acceptable interventions that are

  7. Escape from Freedom: Towards the Political Realm (United States)

    Dillon, Katrina


    In this paper, the author contends that the ability to create a political realm is dependent upon one's state of freedom. She questions what it means to be free and whether assumptions of the definitions of this concept are always good or beneficial. After discussing some of the known theories about freedom, she states that schools are some…


    African Journals Online (AJOL)


    Sep 2, 2010 ... A modified Delphi-technique was used to measure the judgement of a group of experts for the purpose of making ... in the primary health care setting (Bass, Wilson & Griffith 2003:1037). The REALM-R is designed to ... South Africans may not benefit from health promotion materials currently used in primary ...


    Directory of Open Access Journals (Sweden)



    Full Text Available Two tectono-sedimentary domains, which were deformed during the Neogene and evolved into two large structural sectors, characterize the Sicilian Jurassic: the Maghrebides and Peloritani. Africa margin sediments, passing downward to Triassic successions and perhaps originally to Paleozoic deposits, characterize the former. The latter belongs to the European "Calabrian Arc", where the Jurassic transgressively rests on a continental substrate (i.e. the crystalline Variscan basement. These domains are characterized by four sedimentary facies: shallow platform-derived limestones; condensed seamount-type red limestones; nodular limestones with ammonites; deep radiolarites and shales. These facies are illustrated in a dozen of stratigraphic logs. The drowning of most Triassic-Liassic carbonate platforms or ramps and the deepening of adjacent basins came with inferred Jurassic strike-slip tectonics, connected to the relative movement of Africa (Gondwanan part vs Europe (Laurasian part; the same strike-slip tectonics may have caused scattered intraplate volcanic seamounts found in Maghrebides. During the Jurassic the Maghrebide realm was characterized by the interfingering of basins and carbonate platforms. During the Early and Middle Liassic, carbonate platforms and ramps were dominant. Since Toarcian either radiolarites in some basins or Ammonite-bearing calcareous muds developed with intervening basaltic flows, and were accompanied by condensed pelagic carbonates on the ensialic seamount-type highs. The Peloritani realm displays similar characteristics, but with later transgression on the basement, several strike-slip basins and without any volcanoes.

  10. Logistics Reduction: RFID Enabled Autonomous Logistics Management (REALM) (United States)

    National Aeronautics and Space Administration — The Advanced Exploration Systems (AES) Logistics Reduction (LR) project Radio-frequency identification (RFID) Enabled Autonomous Logistics Management (REALM) task...

  11. Computational visual ecology in the pelagic realm. (United States)

    Nilsson, Dan-E; Warrant, Eric; Johnsen, Sönke


    Visual performance and visual interactions in pelagic animals are notoriously hard to investigate because of our restricted access to the habitat. The pelagic visual world is also dramatically different from benthic or terrestrial habitats, and our intuition is less helpful in understanding vision in unfamiliar environments. Here, we develop a computational approach to investigate visual ecology in the pelagic realm. Using information on eye size, key retinal properties, optical properties of the water and radiance, we develop expressions for calculating the visual range for detection of important types of pelagic targets. We also briefly apply the computations to a number of central questions in pelagic visual ecology, such as the relationship between eye size and visual performance, the maximum depth at which daylight is useful for vision, visual range relations between prey and predators, counter-illumination and the importance of various aspects of retinal physiology. We also argue that our present addition to computational visual ecology can be developed further, and that a computational approach offers plenty of unused potential for investigations of visual ecology in both aquatic and terrestrial habitats.

  12. My Lifelong Learning Realm: An Autoethnography Experiential Learning in Finland (United States)

    Rajbhandari, Mani Man Singh


    My journey to write autoethnography report started with inclination to learn cultural and social phenomena in Finland. This was my realm of learning through experiential learning. The ontological philosophy was perceived through objectivistic and subjectivistic approaches. The lifelong experiential learning realm was a benchmark for me to perceive…

  13. COIN of the Realm: U.S. Counterinsurgency Strategy

    National Research Council Canada - National Science Library

    Wipfli, Ralph; Metz, Steven


    .... On October, 22, 2007, the 21st Century Defense Initiative and the Strategic Studies Institute launched the Future Defense Dilemma series with a day-long seminar entitled "COIN of the Realm: U.S...

  14. On the relationships between the biological realm and the semiotic realm

    Directory of Open Access Journals (Sweden)

    José María Gil


    Full Text Available It could be suggested that every semiotic interpretation is represented in the cognitive systems of an individual. Since they are located in the brain, the cognitive systems have to be biological. However, in some complementary way, the structure and the function of such biological systems are conditioned by semiotic information, and semiotic information has its origin in the cultural environement of the individual. In other words, depending on the point of view, every semiotic interpretation can be considered not only in terms of the social context, but also in terms of the natural world. I aim at showing that Neurocognitive Linguistics (Lamb 1999, 2004, 2005, 2006 helps us to understand that there is a biological basis for the semiotic realm. Concretely, relational networks developed by this neurolinguistic theory (which are neurologically plausible help us to represent (some part of the linguistic and cognitive systems of an individual. Those systems, which must have their biological basis in the brain, allow an individual to produce or to interpret signs, which are not part of such internal systems.

  15. Women's Art in Art Education: Realms, Relevance and Resources, Introduction. (United States)

    Sandell, Renee

    This document consists of remarks introducing a collaborative panel on women's art and art education. By exploring the realms, relevance, and resources on women's art in art education, the panel hoped to address new and continuing issues, and to clarify continuing misunderstandings. The panelists shared the belief that only through consciousness…

  16. What Makes Informal Mentorship in the Medical Realm Effective? (United States)

    Mohtady, Heba A.; Könings, Karen D.; van Merriënboer, Jeroen J. G.


    Informal mentoring is based on a natural match between a junior individual and a senior one who share mutual interests. It usually aids in the professional and personal development of both parties involved. We reviewed the literature regarding factors that make informal mentoring effective within the medical realm, by searching a major academic…

  17. Understanding the role of organizational legitimacy within the realm ...

    African Journals Online (AJOL) Understanding the role of organizational legitimacy within the realm of the community-based conservation approach. Armand RandrianasoloI, Arilova A. RandrianasoloII. Correspondence: Armand Randrianasolo.

  18. Objective and Subjective Ends in Kant's Realm of Ends


    Van Impe, Stijn


    In the Groundwork of the Metaphysics of Morals, Kant assesses his idea of a moral world as a ‘realm of ends’ (‘Reich der Zwecke’) defining it as ‘a whole of all ends in systematic connection (a whole both of rational beings as ends in themselves and the ends of his own that each may set himself)’ (IV:433). The importance of this topic for Kant’s moral philosophy can hardly be overestimated for Kant strikingly holds that ‘Morality consists, then, in the reference of all action to the lawgiving...

  19. Nearby, Well Known. The Parochial Realm of Neighborhoods

    Directory of Open Access Journals (Sweden)

    Margarethe Kusenbach


    urba neighborhoods often fail to notice that their research areas are typically slices of the parochial realm, meaning a social territory that is not unique to cities but also common in suburbs and even small towns. Of course, there can be huge differences between an urban hood and a small town quarter yet both share important characteristics which some urban scholars overlook in their belief that city boundaries, density and diversity, or a certain look and feel guarantee the urban-ness of their research areas.

  20. Measuring benefits of protected area management: trends across realms and research gaps for freshwater systems. (United States)

    Adams, Vanessa M; Setterfield, Samantha A; Douglas, Michael M; Kennard, Mark J; Ferdinands, Keith


    Protected areas remain a cornerstone for global conservation. However, their effectiveness at halting biodiversity decline is not fully understood. Studies of protected area benefits have largely focused on measuring their impact on halting deforestation and have neglected to measure the impacts of protected areas on other threats. Evaluations that measure the impact of protected area management require more complex evaluation designs and datasets. This is the case across realms (terrestrial, freshwater, marine), but measuring the impact of protected area management in freshwater systems may be even more difficult owing to the high level of connectivity and potential for threat propagation within systems (e.g. downstream flow of pollution). We review the potential barriers to conducting impact evaluation for protected area management in freshwater systems. We contrast the barriers identified for freshwater systems to terrestrial systems and discuss potential measurable outcomes and confounders associated with protected area management across the two realms. We identify key research gaps in conducting impact evaluation in freshwater systems that relate to three of their major characteristics: variability, connectivity and time lags in outcomes. Lastly, we use Kakadu National Park world heritage area, the largest national park in Australia, as a case study to illustrate the challenges of measuring impacts of protected area management programmes for environmental outcomes in freshwater systems. © 2015 The Author(s).

  1. Nuclear imaging in the realm of medical imaging

    International Nuclear Information System (INIS)

    Deconinck, Frank


    In medical imaging, information concerning the anatomy or biological processes of a patient is detected and presented on film or screen for interpretation by a reader. The information flow from patient to reader optimally implies: - the emission, transmission or reflection of information carriers, typically photons or sound waves, which have to be correctly modulated by patient information through interactions in the patient; - their detection by adequate imaging equipment preserving essential spectral, spatial and/or temporal information; - the presentation of the information in the most perceivable way; - the observation by an unbiased and trained expert. In reality, only an approximation to this optimal situation is achieved. It is the goal of R and D in the medical imaging field to approach the optimum as much as possible within societal constraints such as patient risk and comfort, economics, etc. First, the basic physical concepts underlying the imaging process will be introduced. Different imaging modalities will then be situated in the realm of medical imaging with some emphasis on nuclear imaging

  2. Following Sadra in the Realm of Imagination and Death

    Directory of Open Access Journals (Sweden)

    M. Piravivanak


    Full Text Available Imagination and death are two mysterious areas of the truth that serve as a buffer zone between sense and reason, world and afterworld. By imagination, we mean imaginary forms, the world of imagination and faculty of imagination. With faculty of imagination, man in the world is able to imagine the transcendental truths and meaning in guise of appropriate imaginary forms, given that imagination relates itself to higher foundation of Being, not to the common sense.Death, which is a buffer zone between the world and afterworld, enables man to observe ideal truths. Abundance of paradise graces is realized through imagination according to the will of paradise people in the ideal world which is the field of spiritualization of bodies and corporealization of spirits.Death and imagination are transcendence from the sensual and entering the abstraction of limbo, from a lower to a higher stage. Then, man reaches an openness in the realm of death and imagination which can never be grasped in sensual stage. Art , the field of imagination , is a death toward divine Beauty. Sadra, in the 7th volume of Asfar Arbae, believes that chaste love of artists helps them gain a clear mind, compassionate spirit and fine view that develop a beauty which is manifestation of divine Beauty.In fact, the artist’s imaginary forms are medium of transcendence to the name of Allah. Then, art, in its original sense, is the death of whatever than God and the manifestation of God’s beauty.

  3. How to Census Marine Life: ocean realm field projects

    Directory of Open Access Journals (Sweden)

    Ron O'Dor


    Full Text Available COML field projects will extend our understanding of ocean diversity, distribution and abundance from the nearshore to the abyssal plains. In nearshore, coastal and the upper ocean zones where diversity is reasonably well known it will add details about ranges, migrations and population size, but in the deep ocean there are still likely millions of new species to be described. Global coverage with standard, economical protocols is the goal in the shallow zones, but demonstrating and calibrating efficient new technologies in the deeps may be all that is possible in the 10 year life of the program. Representative sampling from such challenging habitats as the continental margins, abyssal plains, seamounts, deep sea vents, ice-covered oceans and kilometers deep mid-waters is planned. There is even a plan to reveal the four billion years of evolution in the microbial oceans, but strong global cooperation, participation and investment will be require to make the these vast hidden realms as well know as the human edges. There is great interest and international teams supporting the COML now and its legacy in Ocean Biogeographic Information System (OBIS and Global Biodiversity Information Facility (GBIF will be the foundation of future monitoring and assessment of ocean life.

  4. 77 FR 12103 - Culturally Significant Objects Imported for Exhibition Determinations: “Colorful Realm: Japanese... (United States)


    ... DEPARTMENT OF STATE [Public Notice: 7807] Culturally Significant Objects Imported for Exhibition Determinations: ``Colorful Realm: Japanese Bird-and-Flower Paintings by It[omacr] Jakuch[umacr] (1716-1800... determine that the objects to be included in the exhibition ``Colorful Realm: Japanese Bird-and-Flower...

  5. Objectivity and realms of explanation in academic journal articles concerning sex/gender: a comparison of Gender studies and the other social sciences. (United States)

    Söderlund, Therese; Madison, Guy


    Gender studies (GS) has been challenged on epistemological grounds. Here, we compare samples of peer-reviewed academic journal publications written by GS authors and authors from closely related disciplines in the social sciences. The material consisted of 2805 statements from 36 peer-reviewed journal articles, sampled from the Swedish Gender Studies List, which covers >12,000 publications. Each statement was coded as expressing a lack of any of three aspects of objectivity: Bias, Normativity, or Political activism, or as considering any of four realms of explanation for the behaviours or phenomena under study: Biology/genetics, Individual/group differences, Environment/culture, or Societal institutions. Statements in GS publications did to a greater extent express bias and normativity, but not political activism. They did also to a greater extent consider cultural, environmental, social, and societal realms of explanation, and to a lesser extent biological and individual differences explanations.

  6. Conservation physiology across scales: insights from the marine realm (United States)

    Cooke, Steven J.; Killen, Shaun S.; Metcalfe, Julian D.; McKenzie, David J.; Mouillot, David; Jørgensen, Christian; Peck, Myron A.


    As the field of conservation physiology develops and becomes increasingly integrated with ecology and conservation science, the fundamental concept of scale is being recognized as important, particularly for ensuring that physiological knowledge is contextualized in a manner most relevant to policy makers, conservation practitioners and stakeholders. Failure to consider the importance of scale in conservation physiology—both the challenges and the opportunities that it creates—will impede the ability of this discipline to generate the scientific understanding needed to contribute to meaningful conservation outcomes. Here, we have focused on five aspects of scale: biological, spatial, temporal, allometric and phylogenetic. We also considered the scale of policy and policy application relevant to those five types of scale as well as the merits of upscaling and downscaling to explore and address conservation problems. Although relevant to all systems (e.g. freshwater, terrestrial) we have used examples from the marine realm, with a particular emphasis on fishes, given the fact that there is existing discourse regarding scale and its relevance for marine conservation and management. Our synthesis revealed that all five aspects of scale are relevant to conservation physiology, with many aspects inherently linked. It is apparent that there are both opportunities and challenges afforded by working across scales but, to understand mechanisms underlying conservation problems, it is essential to consider scale of all sorts and to work across scales to the greatest extent possible. Moreover, given that the scales in biological processes will often not match policy and management scales, conservation physiology needs to show how it is relevant to aspects at different policy/management scales, change the scales at which policy/management intervention is applied or be prepared to be ignored. PMID:27293645

  7. Landscape-scale conservation design across biotic realms: sequential integration of aquatic and terrestrial landscapes. (United States)

    Leonard, Paul B; Baldwin, Robert F; Hanks, R Daniel


    Systematic conservation planning has been used extensively throughout the world to identify important areas for maintaining biodiversity and functional ecosystems, and is well suited to address large-scale biodiversity conservation challenges of the twenty-first century. Systematic planning is necessary to bridge implementation, scale, and data gaps in a collaborative effort that recognizes competing land uses. Here, we developed a conservation planning process to identify and unify conservation priorities around the central and southern Appalachian Mountains as part of the Appalachian Landscape Conservation Cooperative (App LCC). Through a participatory framework and sequential, cross-realm integration in spatial optimization modeling we highlight lands and waters that together achieve joint conservation goals from LCC partners for the least cost. This process was driven by a synthesis of 26 multi-scaled conservation targets and optimized for simultaneous representation inside the program Marxan to account for roughly 25% of the LCC geography. We identify five conservation design elements covering critical ecological processes and patterns including interconnected regions as well as the broad landscapes between them. Elements were then subjected to a cumulative threats index for possible prioritization. The evaluation of these elements supports multi-scaled decision making within the LCC planning community through a participatory, dynamic, and iterative process.

  8. Reactor Emergency Action Level Monitor: Volume 2, REALM user's reference guide: Final report

    International Nuclear Information System (INIS)

    Touchton, R.A.


    A User Manual for the Reactor Emergency Action Level Monitor (REALM) expert system prototype is provided in this volume. REALM has been designed to provide expert assistance in the identification of a nuclear power plant emergency situation and the determination of its severity. REALM has been developed as an expert system which can provide sensor interpretation and situation assessment in a real-time processing environment. In its state of development at project completion, these capabilities are used in an off-line (i.e., stand-alone, desktop) fashion to provide emergency preparedness assistance in the areas of emergency classification training and emergency exercise scenario generation. REALM also serves a prototype and stepping-stone for the possible connection to the plant for on-line use. In order to distinguish the off-line system (now complete) from the on-line system (now moving from a research prototype to an installed system), the term ''REALM'' is used to indicate the on-line version, with users in the control room, technical support center, and the emergency operations facility, The off-line version is referred to as ''uREALM.''

  9. The Inner Meaning of Outer Space: Human Nature and the Celestial Realm

    Directory of Open Access Journals (Sweden)

    Timothy L. Hubbard


    Full Text Available Kant argued that humans possess a priori knowledge of space; although his argument focused on a physics of bodies, it also has implications for a psychology of beings. Many human cultures organize stars in the night sky into constellations (i.e., impose structure; attribute properties, behaviors, and abilities to objects in the celestial realm (i.e., impose meaning; and use perceived regularity in the celestial realms in development of calendars, long-range navigation, agriculture, and astrology (i.e., seek predictability and control. The physical inaccessibility of the celestial realm allows a potent source of metaphor, and also allows projection of myths regarding origin and ascension, places of power, and dwelling places of gods, immortals, and other souls. Developments in astronomy and cosmology infl uenced views of human nature and the place of humanity in the universe, and these changes parallel declines in egocentrism with human development. Views regarding alleged beings (e.g., angels, extraterrestrials from the celestial realm (and to how communicate with such beings are anthropocentric and ignore evolutionary factors in physical and cognitive development. It is suggested that in considering views and uses of the celestial realm, we learn not just about the universe, but also about ourselves. *

  10. Synthetic Biology in the FDA Realm: Toward Productive Oversight Assessment. (United States)

    Fatehi, Leili; Hall, Ralph F


    Synthetic biology (SB) is expected to create tremendous opportunities in a wide range of areas, including in foods, therapeutics, and diagnostics subject to regulatory oversight by the United States Food and Drug Administration. At the same time, there is substantial basis for concern about the uncertainties of accurately assessing the human health and environmental risks of such SB products. As such, SB is the latest in a string of emerging technologies that is the subject of calls for new approaches to regulation and oversight that involve "thinking ahead" to anticipate governance challenges upstream of technological development and adopting oversight mechanisms that are both adaptive to new information about risks and reflexive to performance data and feedback on policy outcomes over time. These new approaches constitute a marked departure from the status quo, and their development and implementation will require considerable time, resources, and reallocation of responsibilities. Furthermore, in order to develop an appropriate oversight response, adaptive or otherwise, there is first a need to identify the specific types and natures of applications, uncertainties, and regulatory issues that are likely to pose oversight challenges. This article presents our vision for a Productive Oversight Assessment (POA) approach in which the abilities and deficits of an oversight system are evaluated with the aim of enabling productive decisions (i.e., timely, feasible, effective for achieving desired policy outcomes) about oversight while also building capacity to facilitate broader governance efforts. The value ofPOA is two-fold. First, it will advance the development of a generalizable approach for making productive planning and decision-making about the oversight of any given new technology that presents challenges and uncertainties for any given oversight system whose policy goals are implicated by that technology. Second, this effort can enhance the very processes

  11. How to Use the Marine Realms Information Bank (MRIB) Digital Libraries (United States)

    Lightsom, Frances L.; Allwardt, Alan O.


    Marine Realms Information Bank (MRIB) digital libraries provide access to free online scientific resources about oceans, coasts, and coastal watersheds. MRIB allows category, geographic, and keyword searching, alone or in combination. Instructions for searching the three MRIB libraries and for refining the searches are explained in detail.

  12. Screening Hospitalized Patients for Low Health Literacy: Beyond the REALM of Possibility? (United States)

    Louis, Allison J.; Arora, Vineet M.; Matthiesen, Madeleine I.; Meltzer, David O.; Press, Valerie G.


    As patient-centered education efforts increase, assessing health literacy (HL) becomes more salient. The verbal Brief Health Literacy Screen (BHLS) may have clinical and feasibility advantages over written tools, including the Rapid Estimate of Adult Literacy in Medicine--Revised (REALM-R) and Short Test of Functional Health Literacy in Adults…

  13. National Implications: Implementing the "Ways of Knowing through the Realms of Meaning" for the Improvement of Ethical Conduct (United States)

    Cloud, Michelle; Kritsonis, William Allan


    The intent of this article is to illustrate the effectiveness of using the tenets described in the Ways of Knowing Through the Realms of Meaning by Dr. William Allan Kritsonis (2007) to improve ethical conduct. Ten recommendations to implement the Ways of Knowing Through the Realms of Meaning for the improvement of ethical conduct are provided.…

  14. Uncanny Realm

    DEFF Research Database (Denmark)

    Beloff, Laura


    artificially constructed ones with human cognitive abilities. This is due to the development of biotechnological methods to manipulate or construct new kinds of living organisms that are purposely designed by humans. Likewise, artificial intelligence-systems are being developed to become more autonomous...... and life-like with their sensing and learning abilities. These developments point out that our perceptions of the concepts of natural and artificial are radically changing. Traditionally natural is understood as something coming from nature and not made or caused by humans; and artificial is understood...... as the opposite – not natural, but produced, created or caused by humans. Taking the uncanny valley concept by M. Mori (Mori 1970) as a starting point, the paper will investigate how this concept fits into experiments that are intertwining biological and technological matter. The uncanny valley idea was developed...


    Energy Technology Data Exchange (ETDEWEB)

    M. FISK; W. FENG


    One of the design principles of the Internet is that the network is made more flexible, and therefore useful, by placing functionality in end applications rather than in network infrastructure. Network gateways that violate this principle are considered harmful. This paper demonstrates that such upper-level gateways exist because of realm-specific performance, security, and protocol needs of certain portions of the Internet. Placing this functionality in end hosts is, conversely, harmful to the flexibility of using the Internet to link disparate networks. Requirements are developed for a protocol to allow end-hosts and gateways to negotiate the functionality of these gateways in terms of the needs of both end applications and network realms.

  16. Disentangling 'the social' in social design's engagement with the public realm

    DEFF Research Database (Denmark)

    Markussen, Thomas


    Co-Design’s increasing engagement with the public realm is closely related to the widespread turn towards ‘the social’ in design and design research. However, there is a lack of understanding of how the notion of the social in social design differs from social innovation and social entrepreneurship....... This paper provides an inter-disciplinary examination of research literature with the purpose of positioning social design more firmly in its difference from these other approaches. One of the tangible results is an analytical framework that enables design researchers to grasp what is unique to social design...... and wherein lies the value for the public realm. By developing a set of defining criteria such as aim, modus operandi, social value, locus of design and innovation, and the scale of effects, the paper offers a finegrained disentangling of the social in social design....

  17. Debranding in Fantasy Realms: Perceived Marketing Opportunities within the Virtual World


    Kear Andrew; Bown Gerald Robin; Christidi Sofia


    This paper discusses the application of the concept of debranding within immersive virtual environments. In particular the issue of the media richness and vividness of experience is considered in these experience realms that may not be conducive to traditional branding invasive strategies. Brand equity is generally seen to be the desired outcome of branding strategies and the authors suggest that unless the virtual domains are considered as sacred spaces then brand equity may be compromised. ...

  18. Constructing Uniform Resource Locators (URLs) for Searching the Marine Realms Information Bank (United States)

    Linck, Guthrie A.; Allwardt, Alan O.; Lightsom, Frances L.


    The Marine Realms Information Bank (MRIB) is a digital library that provides access to free online scientific information about the oceans and coastal regions. To search its collection, MRIB uses a Common Gateway Interface (CGI) program, which allows automated search requests using Uniform Resource Locators (URLs). This document provides an overview of how to construct URLs to execute MRIB queries. The parameters listed allow detailed control of which records are retrieved, how they are returned, and how their display is formatted.

  19. The Marine Realms Information Bank, a coastal and marine digital library at USGS (United States)

    Marincioni, Fausto; Lightsom, Frances L.; Riall, Rebecca L.; Linck, Guthrie A.; Aldrich, Thomas C.


    The Marine Realms Information Bank (MRIB) is a distributed geolibrary of the USGS Coastal and Marine Geology Program that (1) prioritizes search and display of information by place (location on the Earth's surface), and (2) links information existing in distributed and independent sources. The MRIB aims to provide easy access to knowledge pertaining to the ocean and the associated atmospheric and terrestrial environments to scientists, decision-makers, and the interested members of the public.

  20. The evaluation of framework conditions for commercial initiatives in the realm of renewable energy of Ukraine


    Rozhko, Alla


    The aim of the thesis is search of the status and prospects of Ukraine in international commercial projects in the realm of renewable energy, which allows analyzing the international investment environment in the study area of Ukraine. The thesis includes the resulting conclusions, which help: (a) to develop theoretical justification of conceptual, legal framework and practical guidelines for the implementation of commercial projects in the field of renewable energy in Ukraine, namely: the es...

  1. An age-calibrated record of upper Campanian – Maastrichtian climate change in the Boreal Realm

    DEFF Research Database (Denmark)

    Thibault, Nicolas Rudolph; Schovsbo, Niels; Harlou, Rikke

    nannofossil chalk is in agreement with planktic biotic events of the latest Cretaceous and matches well with climatic trends of intermediate- and deep-waters from other oceanic basins recorded through benthic foraminiferal d18O (Barrera and Savin, 1999). However, most planktic foraminiferal d18O data do......The latest Cretaceous climate of the Boreal Realm was recorded through high-resolution bulk carbon- and oxygen-stable isotopes and a nannofossil temperature index (NTI) on the Stevns-1 core (Denmark) which recovered 456 m of upper Campanian to basal Danian chalk with ~100% recovery and an excellent...... temperatures (SSTs) in the Boreal Realm. Three warming events punctuate the overall cooling trend of the latest Cretaceous: (1) the late Campanian climatic optimum (73.9–71.6 Ma) is characterized by maximum SSTs of 20°C, (2) the mid-Maastrichtian warming (69.7–68 Ma) is characterized by stable SSTs around 17°C...

  2. Atmospheric multidecadal variations in the North Atlantic realm: proxy data, observations, and atmospheric circulation model studies

    Directory of Open Access Journals (Sweden)

    K. Grosfeld


    Full Text Available We investigate the spatial and temporal characteristics of multidecadal climate variability in the North Atlantic realm, using observational data, proxy data and model results. The dominant pattern of multidecadal variability of SST depicts a monopolar structure in the North Atlantic during the instrumental period with cold (warm phases during 1900–1925 and 1970–1990 (1870–1890 and 1940–1960. Two atmospheric general circulation models of different complexity forced with global SST over the last century show SLP anomaly patterns from the warm and cold phases of the North Atlantic similar to the corresponding observed patterns. The analysis of a sediment core from Cariaco Basin, a coral record from the northern Red Sea, and a long-term sea level pressure (SLP reconstruction reveals that the multidecadal mode of the atmospheric circulation characterizes climate variability also in the pre-industrial era. The analyses of SLP reconstruction and proxy data depict a persistent atmospheric mode at least over the last 300 years, where SLP shows a dipolar structure in response to monopolar North Atlantic SST, in a similar way as the models' responses do. The combined analysis of observational and proxy data with model experiments provides an understanding of multidecadal climate modes during the late Holocene. The related patterns are useful for the interpretation of proxy data in the North Atlantic realm.

  3. Rethinking Data Sharing and Human Participant Protection in Social Science Research: Applications from the Qualitative Realm

    Directory of Open Access Journals (Sweden)

    Dessi Kirilova


    Full Text Available While data sharing is becoming increasingly common in quantitative social inquiry, qualitative data are rarely shared. One factor inhibiting data sharing is a concern about human participant protections and privacy. Protecting the confidentiality and safety of research participants is a concern for both quantitative and qualitative researchers, but it raises specific concerns within the epistemic context of qualitative research. Thus, the applicability of emerging protection models from the quantitative realm must be carefully evaluated for application to the qualitative realm. At the same time, qualitative scholars already employ a variety of strategies for human-participant protection implicitly or informally during the research process. In this practice paper, we assess available strategies for protecting human participants and how they can be deployed. We describe a spectrum of possible data management options, such as de-identification and applying access controls, including some already employed by the Qualitative Data Repository (QDR in tandem with its pilot depositors. Throughout the discussion, we consider the tension between modifying data or restricting access to them, and retaining their analytic value. We argue that developing explicit guidelines for sharing qualitative data generated through interaction with humans will allow scholars to address privacy concerns and increase the secondary use of their data.


    Directory of Open Access Journals (Sweden)

    Laura Bădescu


    Full Text Available Saint Parascheva or Saint Friday (Saint Petca entered the realm of imagination in old Romanian culture through canonical literature. The passage of this character from canonical to apocryphal literature is part of a transfer facilitated by the absence of distinctions between genres in ancient times. The common system of tracing the origins of the most widespread literary types – homilies, hagiographies, folk novels, chronographies, etc. – as well as the specific conditions of reception in ancient times has allowed the moving of the characters from one genre to another, without forcing the limits of plausibility required by certain reading habits and precarious scientific information. Such mutations are not visible predominantly in the case of historical characters that have become characters of an entertaining literature frequently using instruments of the fantastic as being significant when the characters derived from the historical space (see Alexander the Great enter the fantastic realm, which has a long tradition in the literature of entertainment. The work suggests a reception route, as well as a writing route that the canonical character Saint Parascheva traveled passing from religious to apocryphal and folklore literature. Referring to the variant of the legend of Saint Friday from Codex Sturdzanus we would thus like to point out the patterns that facilitated the assimilation of this character in Romanian folklore and thence allowed its access to religious collective memory. Sticking to a route imposed by preestablished labels and stereotype formulae, the legend confirms the mechanisms of production and typology-rendering specific to folklore literature.

  5. Where the waters meet: sharing ideas and experiences between inland and marine realms to promote sustainable fisheries management (United States)

    Cooke, Steven J.; Arlinghaus, Robert; Bartley, Devin M.; Beard, T. Douglas; Cowx, Ian G.; Essington, Timothy E.; Jensen, Olaf P.; Lynch, Abigail J.; Taylor, William W.; Watson, Reg


    Although inland and marine environments, their fisheries, fishery managers, and the realm-specific management approaches are often different, there are a surprising number of similarities that frequently go unrecognized. We contend that there is much to be gained by greater cross-fertilization and exchange of ideas and strategies between realms and the people who manage them. The purpose of this paper is to provide examples of the potential or demonstrated benefits of working across aquatic boundaries for enhanced sustainable management of the world’s fisheries resources. Examples include the need to (1) engage in habitat management and protection as the foundation for fisheries, (2) rethink institutional arrangements and management for open-access fisheries systems, (3) establish “reference points” and harvest control rules, (4) engage in integrated management approaches, (5) reap conservation benefits from the link to fish as food, and (6) reframe conservation and management of fish to better engage the public and industry. Cross-fertilization and knowledge transfer between realms could be realized using environment-independent curricula and symposia, joint scientific advisory councils for management, integrated development projects, and cross-realm policy dialogue. Given the interdependence of marine and inland fisheries, promoting discussion between the realms has the potential to promote meaningful advances in managing global fisheries.

  6. China as an Arctic Great Power. Potential Implications for Greenland and the Danish Realm

    DEFF Research Database (Denmark)

    Nørup Sørensen, Camilla Tenna

    In late January 2018, China released its long-awaited White Paper on China’s Arctic Policy. It represents the culmination of the development of a more confident, proactive and sophisticated Chinese diplomacy in the Arctic and reflects how the Arctic has moved up the Chinese leaders’ foreign...... and security policy agenda and is assigned increasing strategic significance. The policy brief analyses China’s Arctic White Paper focusing on the potential implications for Greenland and the Danish Realm. The policy brief concludes that China’s increasing presence in the Arctic constitutes a challenge as well...... as an opportunity depending on whether Copenhagen and Nuuk are able to find stronger common ground in their approach to China in the Arctic and succeed in establishing open, respectful and constructive dialogue and cooperation on this matter....


    Directory of Open Access Journals (Sweden)

    Tiffanie-Victoria Jones


    Full Text Available Imagine a day when social work is tackled by high collision sports. Athletesactually seek services from social workers becausesocial work profession isthoroughly immersed in the realm of these sports.Presently, that image is justthat – a remote idea that, if realized, would alterthe landscape of the field ofmental health, for the benefit of professional athletes who play high collisionsports. Undergirding this paper is a case study ofa professional athlete whoexperienced the worst case of sports-related braindamage presently documented.This paper includes a detailed analysis of social work core values as applied toathletes. As well, mental illness and psychosocialfactors, specific to athletes isanalyzed. Ultimately, this paper seeks to explorethe social workers’ role inserving the mental health needs of an unconventional clientele – professionalathletes in high collision sports.

  8. G-REALM: A lake/reservoir monitoring tool for drought monitoring and water resources management. (United States)

    Birkett, C. M.; Ricko, M.; Beckley, B. D.; Yang, X.; Tetrault, R. L.


    G-REALM is a NASA/USDA funded operational program offering water-level products for lakes and reservoirs and these are currently derived from the NASA/CNES Topex/Jason series of satellite radar altimeters. The main stakeholder is the USDA/Foreign Agricultural Service (FAS) though many other end-users utilize the products for a variety of interdisciplinary science and operational programs. The FAS utilize the products within their CropExplorer Decision Support System (DSS) to help assess irrigation potential, and to monitor both short-term (agricultural) and longer-term (hydrological) drought conditions. There is increasing demand for a more global monitoring service that in particular, captures the variations in the smallest (1 to 100km2) reservoirs and water holdings in arid and semi-arid regions. Here, water resources are critical to both agriculture and regional security. A recent G-REALM 10-day resolution product upgrade and expansion has allowed for more accurate lake level products to be released and for a greater number of water bodies to be monitored. The next program phase focuses on the exploration of the enhanced radar altimeter data sets from the Cryosat-2 and Sentinel-3 missions with their improved spatial resolution, and the expansion of the system to the monitoring of 1,000 water bodies across the globe. In addition, a new element, the monitoring of surface water levels in wetland zones, is also being introduced. This aims to satisfy research and stakeholder requirements with respect to programs examining the links between inland fisheries catch potential and declining water levels, and to those monitoring the delicate balance between water resources, agriculture, and fisheries management in arid basins.

  9. Promising lines of investigations in the realms of laboratory astrophysics with the aid of powerful lasers

    International Nuclear Information System (INIS)

    Belyaev, V. S.; Batishchev, P. A.; Bolshakov, V. V.; Elkin, K. S.; Karabadzhak, G. F.; Kovkov, D. V.; Matafonov, A. P.; Raykunov, G. G.; Yakhin, R. A.; Pikuz, S. A.; Skobelev, I. Yu.; Faenov, A. Ya.; Fortov, V. E.; Krainov, V. P.; Rozanov, V. B.


    The results of work on choosing and substantiating promising lines of research in the realms of laboratory astrophysics with the aid of powerful lasers are presented. These lines of research are determined by the possibility of simulating, under laboratory conditions, problematic processes of presentday astrophysics, such as (i) the generation and evolution of electromagnetic fields in cosmic space and the role of magnetic fields there at various spatial scales; (ii) the mechanisms of formation and evolution of cosmic gamma-ray bursts and relativistic jets; (iii) plasma instabilities in cosmic space and astrophysical objects, plasma jets, and shock waves; (iv) supernova explosions and mechanisms of the explosion of supernovae featuring a collapsing core; (v) nuclear processes in astrophysical objects; (vi) cosmic rays and mechanisms of their production and acceleration to high energies; and (vii) astrophysical sources of x-ray radiation. It is shown that the use of existing powerful lasers characterized by an intensity in the range of 10 18 –10 22 W/cm 2 and a pulse duration of 0.1 to 1 ps and high-energy lasers characterized by an energy in excess of 1 kJ and a pulse duration of 1 to 10 ns makes it possible to perform investigations in laboratory astrophysics along all of the chosen promising lines. The results obtained by experimentally investigating laser plasma with the aid of the laser facility created at Central Research Institute of Machine Building (TsNIIMash) and characterized by a power level of 10 TW demonstrate the potential of such facilities for performing a number of experiments in the realms of laboratory astrophysics.

  10. Old Nordic and Christian elements in Saami ideas about the realm of the dead

    Directory of Open Access Journals (Sweden)

    Olof Pettersson


    Full Text Available The fact that a word or concept has been borrowed from outside does not mean that the original content, the original ideas which the loan word in question expresses, have also been adopted. This is by no means the case when it is a question of abstract words and notions, such as the afterlife. A word, an idea, a custom is taken over but filled with new content; in its new context it acquires a genuinely Saami conceptual load, which has its original domiciliary rights in Saami, north Eurasian culture. The present brief notes on the Nordic and Christian influence on Saami ideas about the realm of the dead proceed from the Saami religion as a whole, examining and explaining it from an external perspective: what connecting-points are there in the "original" mother tradition for the new ideas which have been adopted over the course of time and which have been grafted on to the old? The first and fundamental starting-point for the study of the meeting of the Saami religion with the old Nordic and Christian ones will be the Saami religion itself in its Finno-Ugric and North Euroasiancontext and not the old Norse or Christian beliefs. The question is what has inspired ideas: Are they ideas which have emerged from the Saamis' own religion, or are these ideas the result of old Norse/Christian influence? As far as old Norse influence is concerned, its relevance seems to be limited to the saivo concept. The sources for Saami religion which we possess are not primary sources, which go back to the Lapps themselves; they have been assembled by outsiders. Those who compiled these records were "children of their time" and bound by the conceptual models of the day and by the frames of reference of their religion—Christianity. The Saami realm of death, Jabmeaimo, is Saami in character, with certain Christian elements (purgatory, heaven–hell, heavenly god–devil.

  11. Utilizing the Six Realms of Meaning in Improving Campus Standardized Test Scores through Team Teaching and Strategic Planning (United States)

    Stevenson, Rosnisha D.; Kritsonis, William Allan


    This article will seek to utilize Dr. William Allan Kritsonis' book "Ways of Knowing Through the Realms of Meaning" (2007) as a framework to improve a campus's standardized test scores, more specifically, their TAKS (Texas Assessment of Knowledge and Skills) scores. Many campuses have an improvement plan, also known as a Campus…

  12. Synthetic biology stretching the realms of possibility in wine yeast research. (United States)

    Jagtap, Umesh B; Jadhav, Jyoti P; Bapat, Vishwas A; Pretorius, Isak S


    It took several millennia to fully understand the scientific intricacies of the process through which grape juice is turned into wine. This yeast-driven fermentation process is still being perfected and advanced today. Motivated by ever-changing consumer preferences and the belief that the 'best' wine is yet to be made, numerous approaches are being pursued to improve the process of yeast fermentation and the quality of wine. Central to recent enhancements in winemaking processes and wine quality is the development of Saccharomyces cerevisiae yeast strains with improved robustness, fermentation efficiencies and sensory properties. The emerging science of Synthetic Biology - including genome engineering and DNA editing technologies - is taking yeast strain development into a totally new realm of possibility. The first example of how future wine strain development might be impacted by these new 'history-making' Synthetic Biology technologies, is the de novo production of the raspberry ketone aroma compound, 4-[4-hydroxyphenyl]butan-2-one, in a wine yeast containing a synthetic DNA cassette. This article explores how this breakthrough and the imminent outcome of the international Yeast 2.0 (or Sc2.0) project, aimed at the synthesis of the entire genome of a laboratory strain of S. cerevisiae, might accelerate the design of improved wine yeasts. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. A Need for Education in Water Sustainability in the Agricultural Realm (United States)

    Krajewski, J.


    This study draws upon the definition of water sustainability from the National Water Research Institute as the continual supply of clean water for human uses and for other living beings without compromising the water welfare of future generations. Currently, the greatest consumer of water resources worldwide is irrigation. The move from small-scale, family farms towards corporately owned and market driven, mass scale operations have drastically increased corn production and large-scale factory hog farming in the American Midwest—and the water quality related costs associated with this shift are well-documented. In the heart of the corn belt, the state of Iowa has dealt with issues over the past two decades ranging from flooding of historic proportions, to yield destroying droughts. Most recently, the state's water quality is intensely scrutinized due to nutrient levels higher than almost anywhere else in the world. While the changed agricultural landscape is ultimately responsible for these environmental costs, they can be mitigated if the farmers adopt practices that support water sustainability. However, many Iowa farmers have yet to embrace these necessary practices because of a lack of proper education in this context. Thus, the purpose of this paper is to explore how water sustainability is being conceptualized within the agricultural realm, and ultimately, how the issues are being communicated and understood within various subgroups in Iowa, such as the farmers, the college students, and the general public.

  14. Landscape and Urban Governance: Participatory Planning of the Public Realm in Saida, Lebanon

    Directory of Open Access Journals (Sweden)

    Jala Makhzoumi


    Full Text Available The political shift in Lebanon since the 1990s towards market-led development has encouraged the incremental appropriation of public spaces and state lands, and their conversion into gated, monitored enclaves that serve a privileged few. The process disregards the role of the urban public realm and undermines its potential as an inclusive space and enabling platform for urban governance. This article advocates a participatory approach to urban development, one that engages local stakeholders, institutions, and the public at large as active partners working towards sustainable urban futures. We draw on a case study in Saida, Lebanon, to illustrate participatory planning methods and demonstrate the role of landscape architects in enabling community-led development that is place responsive and sensitive to local narratives of heritage and identity. The project’s participatory methodology and landscape architecture’s expansive framing, the paper argues, democratizes the planning process and contributes to urban governance that empowers local authorities and local stakeholders in the face of privatization and market-led development.

  15. Quirky quarks. A cartoon guide to the fascinating realm of physics

    International Nuclear Information System (INIS)

    Bahr, Benjamin; Lemmer, Boris; Piccolo, Rina


    Do you love quantum physics, cosmology, and the humor behind the popular television show The Big Bang Theory? Have you been on the lookout for a fun, non-technical explanation of the science behind things like time travel, wormholes, antimatter, and dark energy? You'll find all of that, and more, inside this fact-filled, cartoon-packed book. In Quirky Quarks: A Cartoon Guide to the Fascinating Realm of Physics you'll get: The latest science behind the mysteries of our universe explained in common everyday language. A major dose of cartoons, comics, and humor. A good grasp on the often-bizarre nature of reality. Start reading and you'll find that hard science does not have to be hard. Whether you're a teacher, a physicist, or just a lover of the curious, this is the book that delivers the facts in an engaging and entertaining cartoon world inhabited by two dogs, a cat, and some very quirky quarks which you might know from The Particle Zoo. With cutting edge science articles by physicists Boris Lemmer and Benjamin Bahr, and drawings by cartoonist Rina Piccolo, this may be the most fun science reading you're likely to find out there.

  16. Quirky quarks. A cartoon guide to the fascinating realm of physics

    Energy Technology Data Exchange (ETDEWEB)

    Bahr, Benjamin; Lemmer, Boris; Piccolo, Rina


    Do you love quantum physics, cosmology, and the humor behind the popular television show The Big Bang Theory? Have you been on the lookout for a fun, non-technical explanation of the science behind things like time travel, wormholes, antimatter, and dark energy? You'll find all of that, and more, inside this fact-filled, cartoon-packed book. In Quirky Quarks: A Cartoon Guide to the Fascinating Realm of Physics you'll get: The latest science behind the mysteries of our universe explained in common everyday language. A major dose of cartoons, comics, and humor. A good grasp on the often-bizarre nature of reality. Start reading and you'll find that hard science does not have to be hard. Whether you're a teacher, a physicist, or just a lover of the curious, this is the book that delivers the facts in an engaging and entertaining cartoon world inhabited by two dogs, a cat, and some very quirky quarks which you might know from The Particle Zoo. With cutting edge science articles by physicists Boris Lemmer and Benjamin Bahr, and drawings by cartoonist Rina Piccolo, this may be the most fun science reading you're likely to find out there.

  17. Understanding modern and past sedimentary processes in selected lakes from the High Arctic and the Mediterranean realm


    Francke, Alexander


    Lacustrine sediment sequences can provide valuable archives of past environmental and climatological variability in terrestrial realms. In order to unravel the history of a lake and of a lake’s catchment, a profound understanding of the sedimentary processes is required. This encompasses the supply of allochthonous organic matter, nutrients and clastic material to the lake, the subsequent redistribution within the lake as well as autochthonous organic matter and mineral deposition. These lake...

  18. Spiritual versus religious identity: a necessary distinction in understanding clinicians' behavior and attitudes toward clinical practice and medical student teaching in this realm. (United States)

    McEvoy, Mimi; Burton, William; Milan, Felise


    Social sciences view spirituality and religion separately; medicine views them together. We identified distinctions regarding clinical practice and teaching among clinician educators based on their self-identified spirituality versus religiosity. We emailed a 24-item survey on spiritual/religious (S/R) issues to clinician educators (n = 1067) at our institution. Three summary scales were created. Responses to statements, 'I consider myself to be spiritual' and 'I consider myself to be religious' generated four comparison groups: 'spiritual only,' 'religious only,' 'both spiritual and religious' and 'neither.' Analyses employed ANOVA and T tests. A total of 633 (59%) surveys were completed. Four percentage self-identified as 'religious only'; remaining respondents divided evenly, about 30% into each of the other categories. Groups differed from one another on all summary scales (p religious only' group regarding teaching. The 'spiritual and religious' group had the highest mean ratings for all summary scales. The 'neither' and 'religious only' group had the lowest mean ratings. Clinicians' spiritual versus religious identity is associated with differences in behavior/attitudes regarding S/R toward clinical practice and medical student teaching. These findings elucidate opportunities for faculty development to explore effects of beliefs on behavior and attitudes within this realm.

  19. An Efficient and Provably Secure Cross-Realm Client-to-Client Password-Authenticated Key Agreement Protocol with Smart Cards (United States)

    Jin, Wenting; Xu, Jing

    Cross-realm client-to-client password-authenticated key agreement (C2C-PAKA) protocols provide an authenticated key exchange between two clients of different realms, who only share their passwords with their own servers. Recently, several such cross-realm C2C-PAKA protocols have been suggested in the private-key (symmetric) setting, but all of these protocols are found to be vulnerable to password-compromise impersonation attacks. In this paper, we propose our innovative C2C- PAKA-SC protocol in which smart cards are first utilized in the cross-realm setting so that it can resist all types of common attacks including password-compromise impersonation attacks and provide improved efficiency. Moveover, we modify the original formal security model to adapt our proposed protocol and present a corresponding security proof.

  20. The Impact of Mathematics Teachers' Effectiveness on Students' Learning in the Two Realms of: Knowledge and Understanding

    Directory of Open Access Journals (Sweden)

    Nafiseh Ramezani-Monfared


    Full Text Available Effective teachers focus on the students' appropriate academic achievement and have positive impact on their performance. The need to evaluate the effectiveness of teachers on students' performance and learning areas seems necessary. This study was conducted with the aim to investigate the effectiveness of mathematics teachers on the learning of high school second-grade female students. Considering this purpose, survey research method was used. The population of this study included female mathematics teachers of girl high schools as well as female high school students of the zone 1 of Qom city during the school year 2013-2014. In the present study, quasi-cluster sampling method was used and the second grade was selected from among all the grades of the high schools in zone 1 of Qom city, and the study was conducted on 15 female mathematics teachers in this grade and 359 female students of these teachers. Using a questionnaire and a mathematics test, Mann-Whitney statistical results showed that mathematics scores of students who had effective teachers, were lower in the realm of knowledge compared to the students who did not have effective teachers, and mathematics scores of students who had effective teachers, in the realm of understanding were higher, compared to the students who did not have effective teachers.

  1. Three-dimensional electron realm in VSe2 by soft-x-ray photoelectron spectroscopy: origin of charge-density waves. (United States)

    Strocov, Vladimir N; Shi, Ming; Kobayashi, Masaki; Monney, Claude; Wang, Xiaoqiang; Krempasky, Juraj; Schmitt, Thorsten; Patthey, Luc; Berger, Helmuth; Blaha, Peter


    The resolution of angle-resolved photoelectron spectroscopy (ARPES) in three-dimensional (3D) momentum k is fundamentally limited by ill defined surface-perpendicular wave vector k(perpendicular) associated with the finite photoelectron mean free path. Pushing ARPES into the soft-x-ray energy region sharpens the k(perpendicular) definition, allowing accurate electronic structure investigations in 3D materials. We apply soft-x-ray ARPES to explore the 3D electron realm in a paradigm transition metal dichalcogenide VSe2. Essential to break through the dramatic loss of the valence band photoexcitation cross section at soft-x-ray energies is the advanced photon flux performance of our synchrotron instrumentation. By virtue of the sharp 3D momentum definition, the soft-x-ray ARPES experimental band structure and Fermi surface of VSe2 show a textbook clarity. We identify pronounced 3D warping of the Fermi surface and show that its concomitant nesting acts as the precursor for the exotic 3D charge-density waves in VSe2. Our results demonstrate the immense potential of soft-x-ray ARPES to explore details of 3D electronic structure.

  2. Populating the Large-Wavevector Realm: Bloch Volume Plasmon Polaritons in Hyperbolic and Extremely Anisotropic Metamaterials

    DEFF Research Database (Denmark)

    Zhukovsky, Sergei; Babicheva, Viktoriia; Orlov, A. A.


    Optics of hyperbolic metamaterials is revisited in terms of large-wavevector waves, evanescent in isotropic media but propagating in presence of extreme anisotropy. Identifying the physical nature of these waves as Bloch volume plasmon polaritons, we derive their existence conditions and outline ...

  3. Implications for anomalous mantle pressure and dynamic topography from lithospheric stress patterns in the North Atlantic Realm

    DEFF Research Database (Denmark)

    Schiffer, Christian; Nielsen, Søren Bom


    With convergent plate boundaries at some distance, the sources of the lithospheric stress field of the North Atlantic Realm are mainly mantle tractions at the base of the lithosphere, lithospheric density structure and topography. Given this, we estimate horizontal deviatoric stresses using a wel...... of a buoyancy anomaly at the base of the North Atlantic lithosphere at or slightly before continental breakup, relatively fast dissipation of the fringes of this, and continued melt generation below Iceland....... and Azores melt anomalies, as well as topography are able to explain the general pattern of the principle horizontal stress directions. The Iceland melt anomaly overprints the classic ridge push perpendicular to the Mid Atlantic ridge and affects the conjugate passive margins in East Greenland more than...

  4. From land to water: bringing dielectric elastomer sensing to the underwater realm (United States)

    Walker, Christopher; Anderson, Iain


    Since the late 1990's dielectric elastomers (DEs) have been investigated for their use as sensors. To date, there have been some impressive developments: finger displacement controls for video games and integration with medical rehabilitation devices to aid patient recovery. It is clear DE sensing is well established for dry applications, the next frontier, however, is to adapt this technology for the other 71% of the Earth's surface. With proven and perhaps improved water resistance, many new applications could be developed in areas such as diver communication and control of underwater robotics; even wearable devices on land must withstand sweat, washing, and the rain. This study investigated the influence of fresh and salt water on DE sensing. In particular, sensors have been manufactured with waterproof connections and submersed in fresh and salt water baths. Temperature and resting capacitance were recorded. Issues with the basic DE sensor have been identified and compensated for with modifications to the sensor. The electrostatic field, prior and post modification, has been modeled with ANSYS Maxwell. The aim of this investigation was to identify issues, perform modifications and propose a new sensor design suited to wet and underwater applications.

  5. Evolutionary force in confamiliar marine vertebrates of different temperature realms: adaptive trends in zoarcid fish transcriptomes

    Directory of Open Access Journals (Sweden)

    Windisch Heidrun Sigrid


    Full Text Available Abstract Background Studies of temperature-induced adaptation on the basis of genomic sequence data were mainly done in extremophiles. Although the general hypothesis of an increased molecular flexibility in the cold is widely accepted, the results of thermal adaptation are still difficult to detect at proteomic down to the genomic sequence level. Approaches towards a more detailed picture emerge with the advent of new sequencing technologies. Only small changes in primary protein structure have been shown to modify kinetic and thermal properties of enzymes, but likewise for interspecies comparisons a high genetic identity is still essential to specify common principles. The present study uses comprehensive transcriptomic sequence information to uncover general patterns of thermal adaptation on the RNA as well as protein primary structure. Results By comparing orthologous sequences of two closely related zoarcid fish inhabiting different latitudinal zones (Antarctica: Pachycara brachycephalum, temperate zone: Zoarces viviparus we were able to detect significant differences in the codon usage. In the cold-adapted species a lower GC content in the wobble position prevailed for preserved amino acids. We were able to estimate 40-60% coverage of the functions represented within the two compared zoarcid cDNA-libraries on the basis of a reference genome of the phylogenetically closely related fish Gasterosteus aculeatus. A distinct pattern of amino acid substitutions could be identified for the non-synonymous codon exchanges, with a remarkable surplus of serine and reduction of glutamic acid and asparagine for the Antarctic species. Conclusion Based on the differences between orthologous sequences from confamiliar species, distinguished mainly by the temperature regimes of their habitats, we hypothesize that temperature leaves a signature on the composition of biological macromolecules (RNA, proteins with implications for the transcription and

  6. National Agenda: A Holistic Approach towards Development of the Campus Improvement Plan Using "Ways of Knowing through the Realms of Meaning" as the Framework (United States)

    Cloud, Michelle; Kritsonis, William Allan


    This article seeks to examine "Ways of Knowing Through the Realms of Meaning" (2007) by Dr. William Allan Kritsonis as a framework that transformational educational leaders can use to guide members of the Site Based Decision Making Team through development of the Campus Improvement Plan. The Campus Improvement Plan serves as a blueprint for…

  7. Reading between the lines. Czesław Miłosz’s Native Realm. A Search for Self-Definition and its English/American translation

    Directory of Open Access Journals (Sweden)

    Bartłomiej Biegajło


    Full Text Available The aim of this article is to discuss the problem of translating Polish prose, based on an analysis of a selection of samples taken from Czesław Miłosz’s Native Realm. A Search for Self-Definition translated by Catherine S. Leach. The book documents specific relations between the Western and the Eastern Europe determined by historical provenance of the realms in question. The dichotomy of the collective European history has a profound influence on the reception of Polish literature among the Western audience. Native Realm showcases the issue perfectly – it is interesting in terms of its careful account of the historical and social development of the Continent. The perception of reality is conditioned by an inherent dissimilarity of experiences between the West and the East. The intention of Miłosz was to provide an analysis of them and produce an insightful book addressed specifically to the Western readership. My discussion is an attempt to prove that the endeavour is doomed to failure due to the intrinsic differences between the cultures involved, as cultural inheritance determines the interpretation of historical facts and prompts dissimilar connotations. In the case of Native Realm, on the one hand, we encounter Miłosz’s vision/imagination that is irreversibly rooted in the Slavic way of looking at things and, on the other, the distinctively dissimilar Western vantage point. Translating these differences appears to be a major challenge for any translator.

  8. Palaeoenvironments and palaeoceanography changes across the Jurassic/Cretaceous boundary in the Arctic realm: case study of the Nordvik section (north Siberia, Russia)

    Czech Academy of Sciences Publication Activity Database

    Zakharov, V. A.; Rogov, M. A.; Dzyuba, O. S.; Žák, Karel; Košťák, M.; Pruner, Petr; Skupien, P.; Chadima, Martin; Mazuch, M.; Nikitenko, B. L.


    Roč. 33, 25 March (2014) ISSN 0800-0395 R&D Projects: GA ČR GA205/07/1365 Institutional research plan: CEZ:AV0Z30130516 Institutional support: RVO:67985831 Keywords : biodiversity * stable isotopes * J/K boundary * Arctic Realm * palaeoceanography Subject RIV: DB - Geology ; Mineralogy Impact factor: 1.141, year: 2014

  9. Distribution of mammal functional diversity in the Neotropical realm: Influence of land-use and extinction risk. (United States)

    González-Maya, José F; Martínez-Meyer, Enrique; Medellín, Rodrigo; Ceballos, Gerardo


    Functional diversity represents a measure of diversity that incorporates the role of species in an ecosystem, and therefore its dynamics and resilience. Assessing its drivers and spatial variation represents an important step forward in our understanding of functional ecosystem dynamics and it is also necessary to achieve a comprehensive conservation planning. In this paper, we assessed mammal functional diversity for the 218 ecoregions within the Neotropical realm. We evaluated the overall influence and spatial variation of species richness, ecoregion extent, intervention and species at risk on functional diversity. Using ordinary least squares and geographically weighted regression modeling approaches, we found that intervened areas and threatened and non-threatened species are the most influential overall drivers of functional diversity. However, we also detected that these variables do not operate equally across scales. Our local analyses indicated both that the variation explained and local coefficients vary spatially depending on the ecoregion and major habitat type. As estimates of functional diversity are based on current distribution of all mammals, negative influence of intervened areas and positive influence of non-threatened species may reflect a potential degradation of functional processes for some ecosystems. Most generally, the negative influence of intervention together with the influence of threatened species indicates that some areas are currently more susceptible to functional diversity loss. Our results help to pinpoint key areas requiring urgent conservation action to reduce natural land-cover loss and areas where threatened species play influential roles on ecosystem functioning.

  10. Seeking a Utopia in the Past to Endure the Present: A Jungian Reading of The Realms of Gold

    Directory of Open Access Journals (Sweden)

    Shahram R. Sistani


    Full Text Available This paper attempts a Jungian approach to Margaret Drabble’s novel The Realms of Gold. Jungian reading has been taken up to unravel the distinctive characteristics which make this novel so unique and popular. The focus of the paper is to classify the main characters of the novel in terms of their psychological types.  In this novel from the beginning the reader is introduced to an atmosphere which is related to the personality of the main character Frances Wingate. Her thoughts are introduced to the readers in form of monologues. By the usage of these monologues and the narrator’s judgments on the characters their psychological types can be implied. The protagonist is compared with the other major characters to illuminate to what extent different types can get along with each other. In Jungian psychology knowing about our psychological type is a crucial issue in the process of individuation. It gets more significance when it comes to opposite sex relationships or generally any kinds of interaction.

  11. Integrated Metagenomic and Metatranscriptomic Analyses of Microbial Communities in the Meso- and Bathypelagic Realm of North Pacific Ocean

    Directory of Open Access Journals (Sweden)

    Deirdre R. Meldrum


    Full Text Available Although emerging evidence indicates that deep-sea water contains an untapped reservoir of high metabolic and genetic diversity, this realm has not been studied well compared with surface sea water. The study provided the first integrated meta-genomic and -transcriptomic analysis of the microbial communities in deep-sea water of North Pacific Ocean. DNA/RNA amplifications and simultaneous metagenomic and metatranscriptomic analyses were employed to discover information concerning deep-sea microbial communities from four different deep-sea sites ranging from the mesopelagic to pelagic ocean. Within the prokaryotic community, bacteria is absolutely dominant (~90% over archaea in both metagenomic and metatranscriptomic data pools. The emergence of archaeal phyla Crenarchaeota, Euryarchaeota, Thaumarchaeota, bacterial phyla Actinobacteria, Firmicutes, sub-phyla Betaproteobacteria, Deltaproteobacteria, and Gammaproteobacteria, and the decrease of bacterial phyla Bacteroidetes and Alphaproteobacteria are the main composition changes of prokaryotic communities in the deep-sea water, when compared with the reference Global Ocean Sampling Expedition (GOS surface water. Photosynthetic Cyanobacteria exist in all four metagenomic libraries and two metatranscriptomic libraries. In Eukaryota community, decreased abundance of fungi and algae in deep sea was observed. RNA/DNA ratio was employed as an index to show metabolic activity strength of microbes in deep sea. Functional analysis indicated that deep-sea microbes are leading a defensive lifestyle.

  12. Realm of Matrices

    Indian Academy of Sciences (India)

    IAS Admin

    a representation of linear transformations and in finding solutions to a system of linear equations [6]. Matrix al- gebra describes not only the study of linear transforma- tions and operators, but it also gives an ..... Heidelberg, 1999. [4]. Bocher Maxime, Introduction To Higher Algebra, Dover Publications,. New York, 2004. [5].

  13. Realm of the comets

    International Nuclear Information System (INIS)

    Weissman, P.R.


    Studies of Jovian perturbations of the orbits of long-period comets led to the concept of the Oort cloud of 180 billion comets at 50,000-150,000 AU from the sun. Several comets are induced to move toward the sun every million years by the passage of a star at a distance of a few light years. The location of the cloud has since been revised to 20,000-100,000 AU, and comets are now accepted as remnant material fron the proto-solar system epoch. The galactic disk and random, close-passing stars may also cause rare, large perturbations in the orbits of the cloud comets, sending large numbers of comets through the inner solar system. The resulting cometary storm is a candidate cause for the wholesale extinction of dinosaurs in the Cretaceous-Terniary transition due to large number of planetesimals, or one large comet, striking the earth, in a short period of time. The IRAS instruments have detected similar clouds of material around other stars

  14. Miocene Antarctic Terrestrial Realm (United States)

    Ashworth, A. C.; Lewis, A.; Marchant, D. R.


    The discovery of several locations in the Transantarctic Mountains that contain macrofossils and pollen is transforming our understanding of late Cenozoic Antarctica. The most southerly location is on the Beardmore Glacier (85.1°S) about 500 km from the South Pole. The environment was an active glacial margin in which plants, insects and freshwater mollusks inhabited the sand and gravel bars and small lakes on an outwash plain. In addition to leaves and wood of dwarf Nothofagus (Southern Beech) shrubs, achenes of Ranunculus (Buttercup), in situ cushion growth forms of mosses and a vascular plant, the assemblages contains various exoskeletal parts of carabid and curculionid beetles and a cyclorrhaphan fly, the shells of freshwater bivalve and gastropod species and a fish tooth. Initially the deposits were assigned a Pliocene age (3.5 Ma) but a mid- to early Miocene age is more probable (c. 14 - 25 Ma) based on correlation of fossil pollen from the deposits with 39Ar/40Ar dated pollen assemblages from the McMurdo Dry Valleys locations. The oldest location within the Dry Valleys also involved an active ice margin but was part of a valley system that was completely deglaciated for intervals long enough for thick paleosols to develop. The Friis Hills fossil deposits of the Taylor Valley region (77.8°S) are at least 19.76 Ma based on the 39Ar/40Ar age of a volcanic ash bed. The valley floor during the non-glacial phases had poorly-drained soils and the extensive development of mossy mires. Wood and leaves of Nothofagus are abundant in lacustrine deposits. The silts of shallow fluvial channels contain abundant megaspores and spiky leaves of the aquatic lycopod Isoetes (Quillwort). Fossils of beetles are also present in these deposits. During the glacial phases, proglacial lakes were surrounded by dwarfed, deciduous Nothofagus shrubs. The youngest fossils recovered from the Dry Valleys are from the Olympus Range (77.5°S) with an age of 14.07 Ma. The environment was an alpine lake that formed behind a recessional moraine. The fossils are mostly those of freshwater organisms including numerous species of diatoms and an ostracod species in which the soft anatomy is preserved. The base of the lake is marked by a moss bed with exceptionally well-preserved stems and leaves of the extant species Drepanocladus longifolius. Pollen evidence from the Cape Roberts borehole in the Ross Sea basin suggests that tundra existed from the Oligocene to the Early Miocene. Fossil evidence from the Dry Valleys locations indicates that organisms that could not inhabit Antarctica today persisted until c. 14 Ma. At 14 Ma there was a shift in glacial regimes from wet- to cold-based, marking a profound and abrupt climatic shift. We hypothesize that this climate change from warmer and wetter to colder and drier conditions caused the extinction of the tundra biota. It seems probable that at least some of the mid-Miocene fossils are of organisms whose descendants evolved in Antarctica during the Paleogene or earlier. An important consequence of this hypothesis is that the Cenozoic climate of Antarctica was warm enough until the mid-Miocene to support vascular plants and insects. This research was funded by NSF OPP 0739693.

  15. Exploring ambiguous realms

    DEFF Research Database (Denmark)

    Clemensen, Nana


    In Hang'ombe Village in rural Zambia, the relative lack of physical boundaries between the activities of family members allow children to observe the actions and discussions of adults on close hand, exposing them to the ambiguities of daily life. Children explore these ambiguities in their intera......In Hang'ombe Village in rural Zambia, the relative lack of physical boundaries between the activities of family members allow children to observe the actions and discussions of adults on close hand, exposing them to the ambiguities of daily life. Children explore these ambiguities...... in their interactions, testing social roles and conventions. This article explores the vigilance and creative agency displayed by Hang'ombe children, in an environment spurring their acquisition of distinct social and discursive skills....

  16. Coins of the Realm (United States)

    Marion, Stacy


    Each year Ethel R. Jones Elementary School in Portage, Indiana picks a theme for the year. This past year the theme was Indiana Jones, so the author decided to fill her classroom with projects based upon ancient civilizations and archaeology. In this article, she describes how her students made Viking-style coins. (Contains 1 online resource.)

  17. Stratigraphic and paleogeographic correlation between the Tethys and the Atlantic realms across the Cretaceous-Paleogene transition: Tunisia, Spain and France (United States)

    Gallala, N.; Zaghbib-Turki, D.; Turki, M. M.; Arenillas, I.; Arz, J. A.; Molina, E.


    Based on the high resolution biostratigraphical analysis, the El Kef (K/Pg boundary stratotype section and GSSP point) and Ellès sections (Tunisia) and the Agost and Caravaca sections (Betic cordillera, Spain), located at Tethyan realms, are showing a complete section in its Cretaceous-Paleogene transition interval may be compared with their neighbors in the Atlantic realm (Bidart section, SW France). At the Tethys realm, all the biozones and subzones are easily recognized by their biomarkers. Even the uppermost Maastrichtian is developed and indicated by P. hantkeninoides. This biomarker is absent at the Atlantic section of middle latitude: (Bidart, SW France). This later are characterized by P. hariaensis biomarker which have larger paleogeographic extension, it is why we have choose to consider this late species as indicator of the uppermost Cretaceous subzone at Atlantic realm and the P. hantkeninoides as indicator of Tethys realm. At El Kef section, the G. cretacea biozone spans 55 cm. It is more expanded than at Agost (12,5 cm), Caravaca (15 cm) relative to the Tethys realm, and to Bidart (10 cm) relative to Atlantic realm but it is nearly expanded than at Ellès section in Tunisia (66 cm). In spite of the reduced G. cretacea biozone expansion at El Kef K/Pg boundary stratotype and the auxiliary sections, Caravaca and Agost sections (Spain), like as elsewhere, at the Bidart (France) and the Ellès section (Tunisia), the Pv. longiapertura FAD is observed at the upper part of the relevant biozone. At the El Kef section the Pv. eugubina zone spans 5.7 m, it is largely expanded than at Caravaca and Agost sections spanning respectively (42 cm and 65 cm), it is also more expanded than at Bidart section (SW France) spanning 107 cm. But it is approximately equivalent than Elles (5.8 m). This zone is subdivided into Pv. sabina and E. simplicissima subzones. The deposition thickness of the zones and subzones are less expanded than at El Kef and Elles sections. This

  18. A groundwater-planning toolkit for the main Karoo basin: Identifying ...

    African Journals Online (AJOL)

    This paper provides an overview of groundwater-planning tools that were developed during a Water Research Commission project that was initiated due to the need to place the significant knowledge on groundwater of the Karoo Basin within the realms of water resource planning. In essence, the project aimed to identify ...

  19. From the Consulting Room to the Court Room? Taking the Clinical Model of Responsibility Without Blame into the Legal Realm (United States)

    Lacey, Nicola; Pickard, Hanna


    Within contemporary penal philosophy, the view that punishment can only be justified if the offender is a moral agent who is responsible and hence blameworthy for their offence is one of the few areas on which a consensus prevails. In recent literature, this precept is associated with the retributive tradition, in the modern form of ‘just deserts’. Turning its back on the rehabilitative ideal, this tradition forges a strong association between the justification of punishment, the attribution of responsible agency in relation to the offence, and the appropriateness of blame. By contrast, effective clinical treatment of disorders of agency employs a conceptual framework in which ideas of responsibility and blameworthiness are clearly separated from what we call ‘affective blame’: the range of hostile, negative attitudes and emotions that are typical human responses to criminal or immoral conduct. We argue that taking this clinical model of ‘responsibility without blame’ into the legal realm offers new possibilities. Theoretically, it allows for the reconciliation of the idea of ‘just deserts’ with a rehabilitative ideal in penal philosophy. Punishment can be reconceived as consequences—typically negative but occasionally not, so long as they are serious and appropriate to the crime and the context—imposed in response to, by reason of, and in proportion to responsibility and blameworthiness, but without the hard treatment and stigma typical of affective blame. Practically, it suggests how sentencing and punishment can better avoid affective blame and instead further rehabilitative and related ends, while yet serving the demands of justice. PMID:24771953

  20. Clumped isotope analyses suggest constant seawater temperatures at the Middle-Late Jurassic transition in the Subboreal realm (United States)

    Wierzbowski, Hubert; Bajnai, David; Wacker, Ulrike; Fiebig, Jens; Rogov, Mikhail


    Clumped isotope analyses were performed on a set of 18 well-preserved belemnite rostra and 4 ammonite shells derived from uppermost Middle-Upper Jurassic strata of the Russian Platform. The aim of the study is to reconstruct palaeoclimatic variations and paleoceanographic changes during and after the Middle-Late Jurassic transition in the Subboreal realm. Previous studies, based on the δ18O values and elemental ratios of belemnite rostra, suggest the presence of a prolonged Late Callovian-Middle Oxfordian cool period with bottom waters at ˜5 °C, followed by a pronounced Late Oxfordian-Late Kimmeridgian warming (by 6.5-9.5 °C) in the epicontinental Middle Russian Sea. The occurrence of cold bottom waters is interpreted as a result of the formation of wide marine connections with the Arctic Sea during a sea-level highstand. As an independent proxy for palaeotemperatures, clumped isotopes could estimate the extent to which the δ18O record is influenced by local salinity variations. Clumped isotope analyses suggest constant bottom water temperatures (˜15 °C) of the Middle Russian Sea during the latest Callovian-earliest Late Kimmeridgian. This questions the previous interpretation of the δ18O record. The Upper Oxfordian-Lower Kimmeridgian decrease in δ18O values, which was previously explained by warming, probably results instead from a decrease in salinity. A decrease in sea level after the Middle-Late Jurassic boundary transgression could have contributed to the enhanced freshwater runoff. Consequently, the limited water exchange in the restricted basin of the Middle Russian Sea probably led to the significant decrease in salinity and water δ18O values.

  1. Identifying sarcopenia. (United States)

    Abellan van Kan, Gabor; Houles, Mathieu; Vellas, Bruno


    The present review describes and discusses the currently available definitions for sarcopenia from consensus studies. Different sarcopenia definitions have been proposed in these last years. Six main approaches to an operative definition of sarcopenia have been identified. Although the first definitions were solely based on the assessment of the amount of muscle mass, current definitions seem to consistently recognize a bi-dimensional nature of sarcopenia. So, these approaches imply the need of simultaneously assessing both age-related quantitative (i.e. amount of muscle mass) and qualitative (i.e. muscle strength and function) declines of skeletal muscle. Although current consensus exists about a bi-dimensional nature, the proposed approaches to measure sarcopenia are characterized by methodological differences. The majority of the operative definitions proposes to assess muscle mass as an index of appendicular muscle mass divided by squared height (evaluated by dual energy X-ray absorptiometry), assess strength using hand-held dynamometers, and assess function by evaluating gait speed at habitual pace over a short distance. Nevertheless, the clinically relevant thresholds and how to combine the three aspects in an operative definition in order to identify sarcopenia are heterogeneous. A main drawback is that supportive empirical data are missing for these conceptual definitions regarding the risk-assessment of different clinically significant adverse outcomes.

  2. Biostratigraphy and assemblage evolution in Planktic Foraminifera across the Cretaceous-Paleogene transition in low latitude, northern and southern Tethys realm: El Kef GSSP, Elles (Tunisia) and Agost, Caravaca (Betic Cordillera, Spain) (United States)

    Gallala, N.; Zaghbib-Turki, D.; Turki, M. M.; Arenillas, I.; Arz, J. A.; Molina, E.


    The detailed planktic foraminiferal biostratigraphic and quantitative study from the Cretaceous-Paleogene (K-Pg) transition interval of the most expanded and continuous sections located in Spanish (Agost, Caravaca) and Tunisian sections (El Kef and Ellès), allows us to establish the zonation and subzonation of this interval and to distinguish four Acme-stages across the K/Pg transition interval of these low latitude sections. The uppermost Maastrichtian in Tunisian and Spanish sections, is characterized by standard planktic foraminiferal zones: Abathomphalus mayaroensis subdivided into Plummerita hantkeninoides Subzones. This index species is absent at middle and high-latitude twice in Atlantic and Antarctic oceans. Consequently, this species is considered to be restricted to the tropical and subtropical deep seawater. The lower Danian is characterized by Guembelitria cretacea, Parvularugoglobigerina eugubina, and Parasubbotina pseudobulloides biozones. The Guembelitria cretacea Zone was subdivided into the Hedbergella holmdelensis and Parvularugoglobigerina longiapertura Subzones; the Parvularugoglobigerina eugubina Zone into the Parvularugoglobigerina sabina and Eoglobigerina simplicissima Subzones; and the Parasubbotina pseudobulloides Zone into the Eoglobigerina trivialis and Subbotina triloculinoides Subzones. These zones and subzones are less expanded at the Caravaca and Agost sections than in Tunisian sections: El Kef (Global Stratotype Section and Point for the K/Pg) and Ellès, but it is sufficiently expanded to analyze correctly the planktic foraminiferal assemblage evolution across the K-Pg transition. Across this transition, at the Tethys area, we have identified four Acme-stages: Acme-stage 0: is typical of the upper Maastrichtian interval is dominated by cosmopolitan species dwelling surface and intermediate seawater. Acme-stage 1: is typical of the G. cretacea Zone and is dominated by Guembelitria species belonging to "Cretaceous survivors" species

  3. The Richard C. Schneider Lecture. New dimensions of neurosurgery in the realm of high technology: possibilities, practicalities, realities. (United States)

    Apuzzo, M L


    computer-oriented micro/stereotactic capabilities, which appear to be unavoidably required as locales for the practice and development of virtual reality-based stations for operative rehearsal, simulation, training, and, ultimately, enhancement of operative events through robotic interfaces. Primary impetus for progress has relied upon new combinations of technologies, disciplines, and industries. Philosophical and practical problems include the spectrum of availability of these methods to the population at large, the training of individuals to properly administer these methods, defining the acceptable envelope of expertise, and maintaining suitable delivery and progress while containing spiraling costs. Advanced neurological surgery and the use and development of high-technology adjuvants require a robust economy that has a populace willing to invest in the luxury of such developments. The current socioeconomic situation is fragile from the standpoint of both economics and attitudes of the patients and health care providers, with diversion of economic resources, redistribution of funding bases, modification of patient referrals, practice styles, and service attitudes undermining progress. Economic pressures have brought high-technology methods under great scrutiny regarding their effectiveness and cost-effectiveness. Reform proposals have specifically targeted technology-oriented services, and the Office of Technology Assessment has recommended increasing the use of managed care providers who look to information on cost-effectiveness and clinical practice guidelines to establish efficient management strategies and issue "report cards." Although the premise is laudable and "gimmickry" needs to be identified, it might be argued that such scrutiny and control might be overbearing and overused, impeding appropriate delivery and progress.

  4. The Triassic detrital units in the East-Mediterranean realm: back-arcs opening and Cimmerian collision (United States)

    Moix, P.; Stampfli, G. M.


    Sandstone and the Bellerophon Fm. This rifting phase is sealed by the Werfen Fm. and the Serla Dolomite. The second phase of rifting is marked by the deposition of the Braies group during the upper Anisian (locally sealed by the latest Anisian-early Carnian Sciliar Dolomite), followed by the deposition of the Buchenstein ("Pietra Verde" pro parte), Wengen (turbiditic sandstones) and San Cassiano Fms until the lower Carnian. This second episode is locally sealed by the Cassian Dolomite and the Val Degano Fm. The third rifting phase is marked by the deposition of the Carnian Dürrenstein Fm, sealed by the late Carnian Raibl Fm. and the Norian Dolomia Principale. On the Turkish transect, the detrital units belonging to the allochthonous series are post-Variscan Anatolian-derived nappes and are often associated with widespread volcanism. They are generally situated at the base of sequences showing shallow marine sedimentation that pass up to pelagic conditions and finish with flysch/wildflysch deposits. The Meliata-Hallstatt "signal" is well-known in the Silická Brezová composite section (Slovakia). The lower to middle Carnian is made of shallow water limestone followed by a rapid subsidence during the lower upper Carnian and the deposition of pelagic limestones, crinoid limestones, calcarenites and micrites themselves followed by Hallstatt Limestones during the entire Norian and lower Rhaetian. The Maliac "signal" is clearly identifiable in the Karaburun Peninsula. The pelagic development made of limestones and radiolarites usually starts during the Spathian above shallow water limestones. The pelagic sedimentation continues during the middle Triassic and the lower Carnian. During the middle Carnian, the sedimentation passes to shallow water limestones and this situation persists during the Upper Triassic and sometimes even higher up. Volcanic events are common in the Spathian and in the Middle Triassic. Late Carnian cherts associated with pillow-lavas of Maliac origin are

  5. An abrupt extinction in the Middle Permian (Capitanian) of the Boreal Realm with a causal link to anoxia, acidification and mercury poisoning (United States)

    Bond, David; Wignall, Paul; Joachimski, Michael; Sun, Yadong; Savov, Ivan; Grasby, Stephen; Beauchamp, Benoit; Blomeier, Dierk


    The controversial Capitanian (Middle Permian, 262 Ma) extinction event is mostly known from equatorial latitudes and consequently its global extent is poorly resolved. We demonstrate that there were two, severe extinctions amongst brachiopods in northern Boreal latitudes (Spitsbergen), in the Middle to Late Permian, separated by a recovery phase. New age dating of the Kapp Starostin Formation of Spitsbergen using strontium and carbon isotopic trends suggests that the first crisis occurred in the Capitanian. This age assignment indicates that this Middle Permian extinction is manifest at higher latitudes. Redox proxies (pyrite framboids and trace metals) show that the Boreal crisis coincided with an intensification of oxygen depletion, implicating anoxia in the extinction scenario. The highly toxic metal mercury becomes enriched in strata at the Middle Permian extinction level implicating death-by-toxicity (and a possible link to volcanism). Finally, the near-total loss of carbonates across the Boreal Realm in the Middle to Late Permian also suggests a role for acidification. New in prep. data from Ellesmere Island, Arctic Canada (samples collected July 2015) tentatively suggests that this potent "three strikes and you're out" extinction mechanism was a Boreal-wide phenomenon. The Late Permian recovery interval saw the appearance of new brachiopod and bivalve taxa alongside survivors, and an increased mollusk dominance, resulting in an assemblage reminiscent of younger Mesozoic assemblages. The subsequent end-Permian mass extinction terminated this Late Permian radiation.

  6. Life in the Oceanic Realms

    Indian Academy of Sciences (India)

    eutrophic,regions with high concentrations of nutrients and high chlorophyll concentrations (1–10 mg l–1 in surface waters). The microscopic phytoplankton in the ocean can be grouped under diatoms, dinoflagellates, silicoflagellates, and nano and picoplanktonic cyanobacteria. Diatoms are the most dominant. Box 1.

  7. Diving into the Creative Realm (United States)

    Culp, Megan


    Just as students should leave their Foundational year of art with a beginning sense of composition, color, value, and materials, so should they be cultivating their creative capacities. With the equipment exercised and the waters tested, students will be prepared to continue their journey; for it is the interplay of personal experience, social…

  8. Life in the Oceanic Realms

    Indian Academy of Sciences (India)

    marine animals and plants were collected during such voyages by the researchers on board the vessels and systematically described. The HMS Beagle with Charles Darwin on board sailed around different oceans for nearly 4 years and this was the beginning of the science of marine biology. This was followed by another ...

  9. Life in the oceanic realms

    Digital Repository Service at National Institute of Oceanography (India)

    Raghukumar, C.

    waters and elevated pri- mary production in the Bay of Bengal. The fertility of the oce- anic water column can be as- sessed by its chlorophyll con- tent and phytoplankton abun- dance.Primaryproductioninthe Arabian Sea varies from 163? 1782 mg C m?2 d?1.... They increase their surface area by chain or colony formation. Most species regulate their internal ionic con- centrations in relation to that in seawater to remain afloat. They also produce and store oil to reduce cell density. Diatoms have an external skeleton...

  10. Continental weathering as a driver of Late Cretaceous cooling: new insights from clay mineralogy of Campanian sediments from the southern Tethyan margin to the Boreal realm (United States)

    Chenot, Elise; Deconinck, Jean-François; Pucéat, Emmanuelle; Pellenard, Pierre; Guiraud, Michel; Jaubert, Maxime; Jarvis, Ian; Thibault, Nicolas; Cocquerez, Théophile; Bruneau, Ludovic; Razmjooei, Mohammad J.; Boussaha, Myriam; Richard, James; Sizun, Jean-Pierre; Stemmerik, Lars


    New clay mineralogical analyses have been performed on Campanian sediments from the Tethyan and Boreal realms along a palaeolatitudinal transect from 45° to 20°N (Danish Basin, North Sea, Paris Basin, Mons Basin, Aquitaine Basin, Umbria-Marche Basin and Tunisian Atlas). Significant terrigenous inputs are evidenced by increasing proportions of detrital clay minerals such as illite, kaolinite and chlorite at various levels in the mid- to upper Campanian, while smectitic minerals predominate and represented the background of the Late Cretaceous clay sedimentation. Our new results highlight a distinct latitudinal distribution of clay minerals, with the occurrence of kaolinite in southern sections and an almost total absence of this mineral in northern areas. This latitudinal trend points to an at least partial climatic control on clay mineral sedimentation, with a humid zone developed between 20° and 35°N. The association and co-evolution of illite, chlorite and kaolinite in most sections suggest a reworking of these minerals from basement rocks weathered by hydrolysis, which we link to the formation of relief around the Tethys due to compression associated with incipient Tethyan closure. Diachronism in the occurrence of detrital minerals between sections, with detrital input starting earlier during the Santonian in the south than in the north, highlights the northward progression of the deformation related to the anticlockwise rotation of Africa. Increasing continental weathering and erosion, evidenced by our clay mineralogical data through the Campanian, may have resulted in enhanced CO2 consumption by silicate weathering, thereby contributing to Late Cretaceous climatic cooling.

  11. Existence does not Have any Extension: Sohrawardi\\'s Theory about Existence not Having any Real Extension and its Usage in the Realm of the Necessary Being through Itself

    Directory of Open Access Journals (Sweden)

    r akbari


    Full Text Available Theories about the dawn of "principality of existence" or "principality of quiddity" stand in the realm of "confusion of term and concept fallacy". It is true that asalat as a term appeared for the first time in Mirdamad's works such as Taqwim al-Iman to mention the problem of principality of existence, but we should notice that its meaning as a concept can be tracked in Suhrawadi's works. If by the term asalat we mean having real extension, as it is used in Mulla Sadra's work, we can, without any doubt, claim that Suhrawardi is among the proponents of principality of quiddity. Proposing the distinction of existence and quiddity by al-Faraby and Avicenna, some philosophers regarded this distinction as a real one. But Suhrawardi, by presenting about nine arguments, claimed that existence remains as a mental predicate and does not have any real extension. He made use of his theory in the realm of the Necessary Being through Itself. Avicenna had claimed that the essence of God is His Existence (al-Haqq mahiyyatuh inniyyatuh but Suhrawardi denied this Avicennan Peripatetic principle. He said that existence has no real extension and so the essence of God cannot be existence. He claimed that here iniyyah means indivisible life (al-Hayat al-Basit. It seems that Mulla Sadra's arguments for demonstrating the principality of existence posed versus Suhrawardi's arguments for the mental nature of existence.

  12. Thoughts on identifiers

    CERN Document Server

    CERN. Geneva


    As business processes and information transactions have become an inextricably intertwined with the Web, the importance of assignment, registration, discovery, and maintenance of identifiers has increased. In spite of this, integrated frameworks for managing identifiers have been slow to emerge. Instead, identification systems arise (quite naturally) from immediate business needs without consideration for how they fit into larger information architectures. In addition, many legacy identifier systems further complicate the landscape, making it difficult for content managers to select and deploy identifier systems that meet both the business case and long term information management objectives. This presentation will outline a model for evaluating identifier applications and the functional requirements of the systems necessary to support them. The model is based on a layered analysis of the characteristics of identifier systems, including: * Functional characteristics * Technology * Policy * Business * Social T...

  13. Identifiability in stochastic models

    CERN Document Server


    The problem of identifiability is basic to all statistical methods and data analysis, occurring in such diverse areas as Reliability Theory, Survival Analysis, and Econometrics, where stochastic modeling is widely used. Mathematics dealing with identifiability per se is closely related to the so-called branch of ""characterization problems"" in Probability Theory. This book brings together relevant material on identifiability as it occurs in these diverse fields.

  14. Identifying Knowledge and Communication

    Directory of Open Access Journals (Sweden)

    Eduardo Coutinho Lourenço de Lima


    Full Text Available In this paper, I discuss how the principle of identifying knowledge which Strawson advances in ‘Singular Terms and Predication’ (1961, and in ‘Identifying Reference and Truth-Values’ (1964 turns out to constrain communication. The principle states that a speaker’s use of a referring expression should invoke identifying knowledge on the part of the hearer, if the hearer is to understand what the speaker is saying, and also that, in so referring, speakers are attentive to hearers’ epistemic states. In contrasting it with Russell’s Principle (Evans 1982, as well as with the principle of identifying descriptions (Donnellan 1970, I try to show that the principle of identifying knowledge, ultimately a condition for understanding, makes sense only in a situation of conversation. This allows me to conclude that the cooperative feature of communication (Grice 1975 and reference (Clark andWilkes-Gibbs 1986 holds also at the understanding level. Finally, I discuss where Strawson’s views seem to be unsatisfactory, and suggest how they might be improved.

  15. Identifying learning styles. (United States)

    Hughes, Grace


    What was the nature of the CPD activity, practice-related feedback and/or event and/or experience in your practice? The article explored different learning styles and outlined some of the models that can be used to identify them. It discussed the limitations of these models, indicating that although they can be helpful in identifying a student's preferred learning style, this is not 'fixed' and might change over time. Learning is also influenced by other factors, such as culture and age.

  16. spatially identifying vulnerable areas

    African Journals Online (AJOL)

    System (SMDSS) to identify factors that make forest and game reserves vulnerable to rampant human induced ... Commission Act, 1999 (Act 571); and Wildlife Resources (Amendment) (Declaration of Game Reserves). Regulations, 1976 ..... A dynamic simulation model of land-use changes in Sudano-sahelian countries of ...

  17. Identifying and Managing Risk. (United States)

    Abraham, Janice M.


    The role of the college or university chief financial officer in institutional risk management is (1) to identify risk (physical, casualty, fiscal, business, reputational, workplace safety, legal liability, employment practices, general liability), (2) to develop a campus plan to reduce and control risk, (3) to transfer risk, and (4) to track and…

  18. Functional knowledge transfer for high-accuracy prediction of under-studied biological processes.

    Directory of Open Access Journals (Sweden)

    Christopher Y Park

    Full Text Available A key challenge in genetics is identifying the functional roles of genes in pathways. Numerous functional genomics techniques (e.g. machine learning that predict protein function have been developed to address this question. These methods generally build from existing annotations of genes to pathways and thus are often unable to identify additional genes participating in processes that are not already well studied. Many of these processes are well studied in some organism, but not necessarily in an investigator's organism of interest. Sequence-based search methods (e.g. BLAST have been used to transfer such annotation information between organisms. We demonstrate that functional genomics can complement traditional sequence similarity to improve the transfer of gene annotations between organisms. Our method transfers annotations only when functionally appropriate as determined by genomic data and can be used with any prediction algorithm to combine transferred gene function knowledge with organism-specific high-throughput data to enable accurate function prediction. We show that diverse state-of-art machine learning algorithms leveraging functional knowledge transfer (FKT dramatically improve their accuracy in predicting gene-pathway membership, particularly for processes with little experimental knowledge in an organism. We also show that our method compares favorably to annotation transfer by sequence similarity. Next, we deploy FKT with state-of-the-art SVM classifier to predict novel genes to 11,000 biological processes across six diverse organisms and expand the coverage of accurate function predictions to processes that are often ignored because of a dearth of annotated genes in an organism. Finally, we perform in vivo experimental investigation in Danio rerio and confirm the regulatory role of our top predicted novel gene, wnt5b, in leftward cell migration during heart development. FKT is immediately applicable to many bioinformatics

  19. Global Microbial Identifier

    DEFF Research Database (Denmark)

    Wielinga, Peter; Hendriksen, Rene S.; Aarestrup, Frank Møller


    -source systems. There is therefore an obvious need to develop a global system of whole microbial genome databases to aggregate, share, mine and use microbiological genomic data, to address global public health and clinical challenges, and most importantly to identify and diagnose infectious diseases. The global...... of microorganisms, for the identification of relevant genes and for the comparison of genomes to detect outbreaks and emerging pathogens. To harness the full potential of WGS, a shared global database of genomes linked to relevant metadata and the necessary software tools needs to be generated, hence the global...... microbial identifier (GMI) initiative. This tool will ideally be used in amongst others in the diagnosis of infectious diseases in humans and animals, in the identification of microorganisms in food and environment, and to track and trace microbial agents in all arenas globally. This will require...

  20. Identifying anterior segment crystals.


    Hurley, I W; Brooks, A M; Reinehr, D P; Grant, G B; Gillies, W E


    A series of 22 patients with crystals in the anterior segment of the eye was examined by specular microscopy. Of 10 patients with hypermature cataract and hyperrefringent bodies in the anterior chamber cholesterol crystals were identified in four patients and in six of the 10 in whom aspirate was obtained cholesterol crystals were demonstrated in three, two of these having shown crystals on specular microscopy. In 10 patients with intracorneal crystalline deposits, cholesterol crystals were f...

  1. Encrypting personal identifiers.


    Meux, E


    STUDY SETTING. A statewide patient discharge database contained only one unique identifier: the social security number (SSN). A method was developed to transform (encrypt) the SSN so that it could be made publicly available, for purposes of linking discharge records, without revealing the SSN itself. The method of encrypting the SSN into a Record Linkage Number (RLN) is described. PRINCIPAL FINDINGS. The same RLN will always result from the same SSN; it is highly improbable that the same RLN ...

  2. How does the quality of a prediction depend on the magnitude of the events under study?

    Directory of Open Access Journals (Sweden)

    S. Hallerberg


    Full Text Available We investigate the predictability of extreme events in time series. The focus of this work is to understand, under which circumstances large events are better predictable than smaller events. Therefore we use a simple prediction algorithm based on precursory structures which are identified via the maximum likelihood principle. Using theses precursory structures we predict threshold crossings in autocorrelated processes of order one, which are either Gaussian, exponentially or Pareto distributed. The receiver operating characteristic curve is used as a measure for the quality of predictions we find that the dependence on the event magnitude is closely linked to the probability distribution function of the underlying stochastic process. We evaluate this dependence on the probability distribution function numerically and in the Gaussian case also analytically. Furthermore, we study predictions of threshold crossings in correlated data, i.e., velocity increments of a free jet flow. The velocity increments in the free jet flow are in dependence on the time scale either asymptotically Gaussian or asymptotically exponential distributed. If we assume that the optimal precursory structures are used to make the predictions, we find that large threshold crossings are for all different types of distributions better predictable. These results are in contrast to previous results, obtained for the prediction of large increments, which showed a strong dependence on the probability distribution function of the underlying process.

  3. On identified predictive control (United States)

    Bialasiewicz, Jan T.


    Self-tuning control algorithms are potential successors to manually tuned PID controllers traditionally used in process control applications. A very attractive design method for self-tuning controllers, which has been developed over recent years, is the long-range predictive control (LRPC). The success of LRPC is due to its effectiveness with plants of unknown order and dead-time which may be simultaneously nonminimum phase and unstable or have multiple lightly damped poles (as in the case of flexible structures or flexible robot arms). LRPC is a receding horizon strategy and can be, in general terms, summarized as follows. Using assumed long-range (or multi-step) cost function the optimal control law is found in terms of unknown parameters of the predictor model of the process, current input-output sequence, and future reference signal sequence. The common approach is to assume that the input-output process model is known or separately identified and then to find the parameters of the predictor model. Once these are known, the optimal control law determines control signal at the current time t which is applied at the process input and the whole procedure is repeated at the next time instant. Most of the recent research in this field is apparently centered around the LRPC formulation developed by Clarke et al., known as generalized predictive control (GPC). GPC uses ARIMAX/CARIMA model of the process in its input-output formulation. In this paper, the GPC formulation is used but the process predictor model is derived from the state space formulation of the ARIMAX model and is directly identified over the receding horizon, i.e., using current input-output sequence. The underlying technique in the design of identified predictive control (IPC) algorithm is the identification algorithm of observer/Kalman filter Markov parameters developed by Juang et al. at NASA Langley Research Center and successfully applied to identification of flexible structures.

  4. Identifying phenomenal consciousness. (United States)

    Schier, Elizabeth


    This paper examines the possibility of finding evidence that phenomenal consciousness is independent of access. The suggestion reviewed is that we should look for isomorphisms between phenomenal and neural activation spaces. It is argued that the fact that phenomenal spaces are mapped via verbal report is no problem for this methodology. The fact that activation and phenomenal space are mapped via different means does not mean that they cannot be identified. The paper finishes by examining how data addressing this theoretical question could be obtained.

  5. Random Cell Identifiers Assignment

    Directory of Open Access Journals (Sweden)

    Robert Bestak


    Full Text Available Despite integration of advanced functions that enable Femto Access Points (FAPs to be deployed in a plug-and-play manner, the femtocell concept still cause several opened issues to be resolved. One of them represents an assignment of Physical Cell Identifiers (PCIs to FAPs. This paper analyses a random based assignment algorithm in LTE systems operating in diverse femtocell scenarios. The performance of the algorithm is evaluated by comparing the number of confusions for various femtocell densities, PCI ranges and knowledge of vicinity. Simulation results show that better knowledge of vicinity can significantly reduce the number of confusions events.

  6. Towards identifying Collaborative Learning groups using Social Media

    Directory of Open Access Journals (Sweden)

    Selver Softic


    Full Text Available This work reports about the preliminary results and ongoing research based upon profiling collaborative learning groups of persons within the social micro-blogging platforms like Twitter that share potentially common interests on special topic. Hereby the focus is held on spontaneously initiated collaborative learning in Social Media and detection of collaborative learning groups based upon their communication dynamics. Research questions targeted to be answered are: are there any useful data mining algorithms to fulfill the task of pre-selection and clustering of users in social networks, how good do they perform, and what are the metrics that could be used for detection and evaluation in the realm of this task. Basic approach presented here uses as preamble hypothesis that users and their interests in Social Networks can be identified through content generated by them and content they consume. Special focus is held on topic oriented approach as least common bounding point. Those should be also the basic criteria used to detect and outline the learning groups. The aim of this work is to deliver first scientific pre-work for successfully implementation of recommender systems using social network metrics and content features of social network users for the purposes of better learning group communication and information consumption.

  7. From palaeotectonics to neotectonics in the Neotethys realm: The importance of kinematic decoupling and inherited structural grain in SW Anatolia (Turkey) (United States)

    ten Veen, J. H.; Boulton, S. J.; Alçiçek, M. C.


    In order to asses young, i.e. "neotectonic" fault kinematics and the relation with plate-tectonic processes in SW Turkey we focused on the questions: 1) what produced the structural grain, i.e. how and when are faults generated, 2) what was/is the kinematic behaviour of these faults and 3) during which period(s) were these faults active? Firstly, the distribution of faults has been investigated using a lineament analysis performed on satellite imagery and digital elevation models. We define five main tectonic domains in SW Turkey: 1 and 2) the Northern and Southern Western Anatolian extensional provinces; 3) the eastern Hellenic arc (including Rhodes Island and the submarine Anaximander mountains); 4) The Lycian Taurides and 5) the western limb of the Isparta Angle. Lineament analysis reveals dominance of three lineament groups, i.e. NNE-, ENE-, and WNW-trending, in all identified domains. Variations in the relative importance of lineament groups exist and are attributed to the specific tectonic evolution of each domain. A synthesis of recently published field data shows that the onset of activity of related fault groups is neither synchronous, nor uniform. The "structural grain" for the neotectonic deformation in SW Turkey is formed during the last stage of palaeotectonic deformation (stage 1), which is dominated by the onset of the Menderes Massif exhumation along a top-N major detachment, the Datça break-away fault [Seyitoğlu, G., Işık, V., and Çemen, İ., 2004. Complete Tertiary exhumation history of the Menderes massif, western Turkey: an alternative working hypothesis. Terra Nova, 16, 358-364.], and related SE-ward sliding of the Lycian Nappes in the footwall of this fault. This stage is characterized by spatially variable types of deformation that are delineated by, from NW to SE, the Datça Fault around the Menderes-Lycian contact zone and the Lycian frontal thrust zone, respectively. The kinematic decoupling along these structures explains the co

  8. Radiograph identifying means

    International Nuclear Information System (INIS)

    Sheldon, A.D.


    A flexible character-indentable plastics embossing tape is backed by and bonded to a lead strip, not more than 0.025 inches thick, to form a tape suitable for identifying radiographs. The lead strip is itself backed by a relatively thin and flimsy plastics or fabric strip which, when removed, allows the lead plastic tape to be pressure-bonded to the surface to be radiographed. A conventional tape-embossing gun is used to indent the desired characters in succession into the lead-backed tape, without necessarily severing the lead; and then the backing strip is peeled away to expose the layer of adhesive which pressure-bonds the indented tape to the object to be radiographed. X-rays incident on the embossed tape will cause the raised characters to show up dark on the subsequently-developed film, whilst the raised side areas will show up white. Each character will thus stand out on the developed film. (author)

  9. Frankl and the Realm of Meaning. (United States)

    Das, Ajit K.


    Presents the importance that meaning and values have in human life, with special reference to Viktor Frankl's work. Points out some pathological phenomena that result from the frustration of the quest for meaning and describes principles of logotherapy to deal with them. (Author)

  10. A tour guide to the latent realm

    NARCIS (Netherlands)

    Borsboom, D.


    Achilles and the tortoise want to predict peoples’ running performance from their age. In determining age the tortoise has cleverly asked his participants for their passports and has noted their date of birth, before letting them run half the distance between Achilles and himself. Achilles, however,

  11. Emotional driving : cocooning in the public realm

    NARCIS (Netherlands)

    Kooijman, D.; Sierksma, R.

    ABSTRACT The concept of postmodernity has been debated intensely. This paper argues its useful, though limited applicability. We analyze it as a new socio-cultural complex, performing necessary socio-reproductive functions, a result of a transformation of the capitalist mode of production. We argue

  12. The New Realm of 3-D Vision (United States)


    Dimension Technologies Inc., developed a line of 2-D/3-D Liquid Crystal Display (LCD) screens, including a 15-inch model priced at consumer levels. DTI's family of flat panel LCD displays, called the Virtual Window(TM), provide real-time 3-D images without the use of glasses, head trackers, helmets, or other viewing aids. Most of the company initial 3-D display research was funded through NASA's Small Business Innovation Research (SBIR) program. The images on DTI's displays appear to leap off the screen and hang in space. The display accepts input from computers or stereo video sources, and can be switched from 3-D to full-resolution 2-D viewing with the push of a button. The Virtual Window displays have applications in data visualization, medicine, architecture, business, real estate, entertainment, and other research, design, military, and consumer applications. Displays are currently used for computer games, protein analysis, and surgical imaging. The technology greatly benefits the medical field, as surgical simulators are helping to increase the skills of surgical residents. Virtual Window(TM) is a trademark of Dimension Technologies Inc.

  13. REALM: an expert system for classifying emergencies

    International Nuclear Information System (INIS)

    Touchton, R.A.; Gunter, A.D.; Cain, D.G.


    In late 1983, EPRI began a program to encourage and stimulate the development of Artificial Intelligence Applications for the nuclear industry. As a part of that effort, EPRI has contracted Technology Applications, Inc., (TAI) to develop an artificially intelligent Emergency Classification system Prototype. This paper presents a description of and a status report on the recently completed prototype

  14. Realm of Thermoalkaline Lipases in Bioprocess Commodities

    Directory of Open Access Journals (Sweden)

    Ahmad Firdaus B. Lajis


    Full Text Available For decades, microbial lipases are notably used as biocatalysts and efficiently catalyze various processes in many important industries. Biocatalysts are less corrosive to industrial equipment and due to their substrate specificity and regioselectivity they produced less harmful waste which promotes environmental sustainability. At present, thermostable and alkaline tolerant lipases have gained enormous interest as biocatalyst due to their stability and robustness under high temperature and alkaline environment operation. Several characteristics of the thermostable and alkaline tolerant lipases are discussed. Their molecular weight and resistance towards a range of temperature, pH, metal, and surfactants are compared. Their industrial applications in biodiesel, biodetergents, biodegreasing, and other types of bioconversions are also described. This review also discusses the advance of fermentation process for thermostable and alkaline tolerant lipases production focusing on the process development in microorganism selection and strain improvement, culture medium optimization via several optimization techniques (i.e., one-factor-at-a-time, surface response methodology, and artificial neural network, and other fermentation parameters (i.e., inoculums size, temperature, pH, agitation rate, dissolved oxygen tension (DOT, and aeration rate. Two common fermentation techniques for thermostable and alkaline tolerant lipases production which are solid-state and submerged fermentation methods are compared and discussed. Recent optimization approaches using evolutionary algorithms (i.e., Genetic Algorithm, Differential Evolution, and Particle Swarm Optimization are also highlighted in this article.

  15. Olfactory coding in the turbulent realm.

    Directory of Open Access Journals (Sweden)

    Vincent Jacob


    Full Text Available Long-distance olfactory search behaviors depend on odor detection dynamics. Due to turbulence, olfactory signals travel as bursts of variable concentration and spacing and are characterized by long-tail distributions of odor/no-odor events, challenging the computing capacities of olfactory systems. How animals encode complex olfactory scenes to track the plume far from the source remains unclear. Here we focus on the coding of the plume temporal dynamics in moths. We compare responses of olfactory receptor neurons (ORNs and antennal lobe projection neurons (PNs to sequences of pheromone stimuli either with white-noise patterns or with realistic turbulent temporal structures simulating a large range of distances (8 to 64 m from the odor source. For the first time, we analyze what information is extracted by the olfactory system at large distances from the source. Neuronal responses are analyzed using linear-nonlinear models fitted with white-noise stimuli and used for predicting responses to turbulent stimuli. We found that neuronal firing rate is less correlated with the dynamic odor time course when distance to the source increases because of improper coding during long odor and no-odor events that characterize large distances. Rapid adaptation during long puffs does not preclude however the detection of puff transitions in PNs. Individual PNs but not individual ORNs encode the onset and offset of odor puffs for any temporal structure of stimuli. A higher spontaneous firing rate coupled to an inhibition phase at the end of PN responses contributes to this coding property. This allows PNs to decode the temporal structure of the odor plume at any distance to the source, an essential piece of information moths can use in their tracking behavior.

  16. The realm of cellulases in biorefinery development. (United States)

    Chandel, Anuj K; Chandrasekhar, G; Silva, Messias Borges; Silvério da Silva, Silvio


    Geopolitical concerns (unstable supply of gasoline, environmental pollution, and regular price hikes), economic, and employment concerns have been prompting researchers, entrepreneurs, and policy makers to focus on harnessing the potential of lignocellulosic feedstock for fuel ethanol production and its commercialization. The carbohydrate skeleton of plant cell walls needs to be depolymerised into simpler sugars for their application in fermentation reactions as a chief carbon source of suitable ethnologic strains for ethanol production. The role of cellulolytic enzymes in the degradation of structural carbohydrates of the plant cell wall into ready-to-fermentable sugar stream is inevitable. Cellulase synergistically acts upon plant cell wall polysaccharides to release glucose into the liquid media. Cellulase predominantly dominates all the plant cell wall degrading enzymes due to their vast and diverse range of applications. Apart from the major applications of cellulases such as in detergent formulations, textile desizing, and development of monogastric feed for ruminants, their role in biorefinery is truly remarkable. This is a major area where new research tools based upon fermentation based formulations, biochemistry, and system biology to expedite the structure-function relationships of cellulases including cellulosomes and new designer enzymatic cocktails are required. In the last two decades, a considerable amount of research work has been performed on cellulases and their application in biomass saccharification. However, there are still technical and economic impediments to the development of an inexpensive commercial cellulase production process. Advancements in biotechnology such as screening of microorganisms, manipulation of novel cellulase encoding traits, site-specific mutagenesis, and modifications to the fermentation process could enhance the production of cellulases. Commercially, cheaper sources of carbohydrates and modified fermentation conditions could lead to more cost-effective production of cellulases with the goal to reduce the cost of ethanol production from lignocellulosics. Implementation of integrated steps like cellulase production and cellulase mediated saccharification of biomass in conjunction with the fermentation of released sugars in ethanol in a single step so called consolidated bio-processing (CBP) is very important to reduce the cost of bioethanol. This paper aims to explore and review the important findings in cellulase biotechnology and the forward path for new cutting edge opportunities in the success of biorefineries.

  17. In the realm of the geometric transitions

    International Nuclear Information System (INIS)

    Alexander, Stephon; Becker, Katrin; Becker, Melanie; Dasgupta, Keshav; Knauf, Anke; Tatar, Radu


    We complete the duality cycle by constructing the geometric transition duals in the type IIB, type I and heterotic theories. We show that in the type IIB theory the background on the closed string side is a Kaehler deformed conifold, as expected, even though the mirror type IIA backgrounds are non-Kaehler (both before and after the transition). On the other hand, the type I and heterotic backgrounds are non-Kaehler. Therefore, on the heterotic side these backgrounds give rise to new torsional manifolds that have not been studied before. We show the consistency of these backgrounds by verifying the torsional equation

  18. Use of Parsimony Analysis to Identify Areas of Endemism of Chinese Birds: Implications for Conservation and Biogeography

    Directory of Open Access Journals (Sweden)

    Xiao-Lei Huang


    Full Text Available Parsimony analysis of endemicity (PAE was used to identify areas of endemism (AOEs for Chinese birds at the subregional level. Four AOEs were identified based on a distribution database of 105 endemic species and using 18 avifaunal subregions as the operating geographical units (OGUs. The four AOEs are the Qinghai-Zangnan Subregion, the Southwest Mountainous Subregion, the Hainan Subregion and the Taiwan Subregion. Cladistic analysis of subregions generally supports the division of China’s avifauna into Palaearctic and Oriental realms. Two PAE area trees were produced from two different distribution datasets (year 1976 and 2007. The 1976 topology has four distinct subregional branches; however, the 2007 topology has three distinct branches. Moreover, three Palaearctic subregions in the 1976 tree clustered together with the Oriental subregions in the 2007 tree. Such topological differences may reflect changes in the distribution of bird species through circa three decades.

  19. Ação coletiva no âmbito da economia solidária e da autogestão Collective action in the realm of solidarity economics and self-management

    Directory of Open Access Journals (Sweden)

    Maria Eugênia Monteiro Castanheira


    Full Text Available Este ensaio traz reflexões sobre as motivações que conduzem a ação coletiva no âmbito da economia solidária e da autogestão, partindo do pressuposto de que, nestas esferas, a ação coletiva se diferencia daquela que se desenvolve nos domínios do capitalismo e daquela que se desenvolve no contexto social das relações tradicionais. Neste sentido, o objetivo deste ensaio é explorar as especificidades teóricas da ação coletiva orientada pelos princípios da economia solidária e da autogestão, tendo como enfoque analítico a teoria da dádiva. Para tanto, procurou-se, de forma articulada e seqüencial, problematizar a economia solidária, evidenciar os elementos constitutivos da autogestão e o aporte teórico da teoria da dádiva. Acredita-se que tais ponderações indicam um campo a ser explorado empiricamente, podendo contribuir para a elaboração de novos estudos e pesquisas sobre este tema.This essay reflects on the motivations that lead to collective action in the realm of solidarity economics and self-management, based on the presumption that, in these spheres, collective action is different from that which takes places in the domains of capitalism and that which develops in the social context of traditional relations. In this sense, the purpose of this essay is to explore the theoretical specificities of collective action guided by the principles of solidarity economics and self-management, with an analytical focus on the theory of donation. To do so, it sought to analyze solidarity economics in an articulated and sequential manner, to reveal the constituent elements of self management and the theoretical support for the theory of donation. These considerations indicate that there is much empirical research to do in this field, and such research can contribute to the elaboration of new studies and research about this issue.

  20. Identifying sources of aeolian mineral dust: Present and past (United States)

    Muhs, Daniel R; Prospero, Joseph M; Baddock, Matthew C; Gill, Thomas E


    Aeolian mineral dust is an important component of the Earth’s environmental systems, playing roles in the planetary radiation balance, as a source of fertilizer for biota in both terrestrial and marine realms and as an archive for understanding atmospheric circulation and paleoclimate in the geologic past. Crucial to understanding all of these roles of dust is the identification of dust sources. Here we review the methods used to identify dust sources active at present and in the past. Contemporary dust sources, produced by both glaciogenic and non-glaciogenic processes, can be readily identified by the use of Earth-orbiting satellites. These data show that present dust sources are concentrated in a global dust belt that encompasses large topographic basins in low-latitude arid and semiarid regions. Geomorphic studies indicate that specific point sources for dust in this zone include dry or ephemeral lakes, intermittent stream courses, dune fields, and some bedrock surfaces. Back-trajectory analyses are also used to identify dust sources, through modeling of wind fields and the movement of air parcels over periods of several days. Identification of dust sources from the past requires novel approaches that are part of the geologic toolbox of provenance studies. Identification of most dust sources of the past requires the use of physical, mineralogical, geochemical, and isotopic analyses of dust deposits. Physical properties include systematic spatial changes in dust deposit thickness and particle size away from a source. Mineralogy and geochemistry can pinpoint dust sources by clay mineral ratios and Sc-Th-La abundances, respectively. The most commonly used isotopic methods utilize isotopes of Nd, Sr, and Pb and have been applied extensively in dust archives of deep-sea cores, ice cores, and loess. All these methods have shown that dust sources have changed over time, with far more abundant dust supplies existing during glacial periods. Greater dust supplies in

  1. Identifying the molecular basis of host-parasite coevolution: merging models and mechanisms. (United States)

    Dybdahl, Mark F; Jenkins, Christina E; Nuismer, Scott L


    Mathematical models of the coevolutionary process have uncovered consequences of host-parasite interactions that go well beyond the traditional realm of the Red Queen, potentially explaining several important evolutionary transitions. However, these models also demonstrate that the specific consequences of coevolution are sensitive to the structure of the infection matrix, which is embedded in models to describe the likelihood of infection in encounters between specific host and parasite genotypes. Traditional cross-infection approaches to estimating infection matrices might be unreliable because evolutionary dynamics and experimental sampling lead to missing genotypes. Consequently, our goal is to identify the likely structure of infection matrices by synthesizing molecular mechanisms of host immune defense and parasite counterdefense with coevolutionary models. This synthesis reveals that the molecular mechanisms of immune reactions, although complex and diverse, conform to two basic models commonly used within coevolutionary theory: matching infection and targeted recognition. Our synthesis also overturns conventional wisdom, revealing that the general models are not taxonomically restricted but are applicable to plants, invertebrates, and vertebrates. Finally, our synthesis identifies several important areas for future research that should improve the explanatory power of coevolutionary models. The most important among these include empirical studies to identify the molecular hotspots of genotypic specificity and theoretical studies examining the consequences of matrices that more accurately represent multistep infection processes and quantitative defenses.

  2. New criteria to identify spectrum

    DEFF Research Database (Denmark)

    Jensen, Arne; Krishna, M.

    In this paper we give some new criteria for identifying the components of a probability measure, in its Lebesgue decomposition. This enables us to give new criteria to identify spectral types of self adjoint operators on Hilbert spaces, especially those of interest....

  3. New criteria to identify spectrum

    DEFF Research Database (Denmark)

    Jensen, Arne; Krishna, M.


    In this paper we give some new criteria for identifying the components of a probability measure, in its Lebesgue decomposition. This enables us to give new criteria to identify spectral types of self-adjoint operators on Hilbert spaces, especially those of interest....

  4. Identifying discharge practice training needs. (United States)

    Lees, L; Emmerson, K

    A training needs analysis tool was developed to identify nurses' discharge training needs and to improve discharge practice. The tool includes 49 elements of discharge practice subdivided into four areas: corporate, operational, clinical and nurse-led discharge. The tool was disseminated to 15 wards on two hospital sites with assistance from the practice development team. Analysis of discharge training is important to assess discharge training needs and to identify staff who may assist with training.

  5. Do Subjective Measures Improve the Ability to Identify Limited Health Literacy in a Clinical Setting? (United States)

    Goodman, Melody S; Griffey, Richard T; Carpenter, Christopher R; Blanchard, Melvin; Kaphingst, Kimberly A


    Existing health literacy assessments developed for research purposes have constraints that limit their utility for clinical practice, including time requirements and administration protocols. The Brief Health Literacy Screen (BHLS) consists of 3 self-administered Single-Item Literacy Screener (SILS) questions and obviates these clinical barriers. We assessed whether the addition of SILS items or the BHLS to patient demographics readily available in ambulatory clinical settings reaching underserved patients improves the ability to identify limited health literacy. We analyzed data from 2 cross-sectional convenience samples of patients from an urban academic emergency department (n = 425) and a primary care clinic (n = 486) in St. Louis, Missouri. Across samples, health literacy was assessed using the Rapid Estimate of Adult Literacy in Medicine-Revised (REALM-R), Newest Vital Sign (NVS), and the BHLS. Our analytic sample consisted of 911 adult patients, who were primarily female (62%), black (66%), and had at least a high school education (82%); 456 were randomly assigned to the estimation sample and 455 to the validation sample. The analysis showed that the best REALM-R estimation model contained age, sex, education, race, and 1 SILS item (difficulty understanding written information). In validation analysis this model had a sensitivity of 62%, specificity of 81%, a positive likelihood ratio (LR(+)) of 3.26, and a negative likelihood ratio (LR(-)) of 0.47; there was a 28% misclassification rate. The best NVS estimation model contained the BHLS, age, sex, education and race; this model had a sensitivity of 77%, specificity of 72%, LR(+) of 2.75, LR(-) of 0.32, and a misclassification rate of 25%. Findings suggest that the BHLS and SILS items improve the ability to identify patients with limited health literacy compared with demographic predictors alone. However, despite being easier to administer in clinical settings, subjective estimates of health literacy have

  6. Identifying tier one key suppliers. (United States)

    Wicks, Steve


    In today's global marketplace, businesses are becoming increasingly reliant on suppliers for the provision of key processes, activities, products and services in support of their strategic business goals. The result is that now, more than ever, the failure of a key supplier has potential to damage reputation, productivity, compliance and financial performance seriously. Yet despite this, there is no recognised standard or guidance for identifying a tier one key supplier base and, up to now, there has been little or no research on how to do so effectively. This paper outlines the key findings of a BCI-sponsored research project to investigate good practice in identifying tier one key suppliers, and suggests a scalable framework process model and risk matrix tool to help businesses effectively identify their tier one key supplier base.

  7. Sparse Linear Identifiable Multivariate Modeling

    DEFF Research Database (Denmark)

    Henao, Ricardo; Winther, Ole


    In this paper we consider sparse and identifiable linear latent variable (factor) and linear Bayesian network models for parsimonious analysis of multivariate data. We propose a computationally efficient method for joint parameter and model inference, and model comparison. It consists of a fully...... Bayesian hierarchy for sparse models using slab and spike priors (two-component δ-function and continuous mixtures), non-Gaussian latent factors and a stochastic search over the ordering of the variables. The framework, which we call SLIM (Sparse Linear Identifiable Multivariate modeling), is validated...... computational complexity. We attribute this mainly to the stochastic search strategy used, and to parsimony (sparsity and identifiability), which is an explicit part of the model. We propose two extensions to the basic i.i.d. linear framework: non-linear dependence on observed variables, called SNIM (Sparse Non-linear...

  8. Football refereeing: Identifying innovative methods

    Directory of Open Access Journals (Sweden)

    Reza MohammadKazemi


    Full Text Available The aim of the present study is to identify the potentials innovation in football industry. Data were collected from 10 national and international referees, assistant referees and referees’ supervisors in Iran. In this study, technological innovations are identified that assist better refereeing performances. The analysis revealed a significant relationship between using new technologies and referees ‘performance. The results indicate that elite referees, assistant referees and supervisors agreed to use new technological innovations during the game. According to their comments, this kind of technology causes the referees’ performance development.

  9. Testing times: identifying puberty in an identified skeletal sample. (United States)

    Henderson, Charlotte Y; Padez, Cristina


    Identifying the onset of puberty in skeletal remains can provide evidence of social changes associated with the onset of adulthood. This paper presents the first test of a skeletal method for identifying stages of development associated with the onset of puberty in a skeletal sample of known age and cause of death. Skeletal methods for assessing skeletal development associated with changes associated with puberty were recorded in the identified skeletal collection in Coimbra, Portugal. Historical data on the onset of menarche in this country are used to test the method. As expected, females mature faster than their male counterparts. There is some side asymmetry in development. Menarche was found to have been achieved by an average age of 15. Asymmetry must be taken into account when dealing with partially preserved skeletons. Age of menarche is consistent, although marginally higher, than the age expected based on historical data for this time and location. Skeletal development in males could not be tested against historical data, due to the lack of counterpart historical data. The ill health known to be present in this prematurely deceased population may have delayed skeletal development and the onset of puberty.

  10. Minimal output sets for identifiability. (United States)

    Anguelova, Milena; Karlsson, Johan; Jirstrand, Mats


    Ordinary differential equation models in biology often contain a large number of parameters that must be determined from measurements by parameter estimation. For a parameter estimation procedure to be successful, there must be a unique set of parameters that can have produced the measured data. This is not the case if a model is not uniquely structurally identifiable with the given set of outputs selected as measurements. In designing an experiment for the purpose of parameter estimation, given a set of feasible but resource-consuming measurements, it is useful to know which ones must be included in order to obtain an identifiable system, or whether the system is unidentifiable from the feasible measurement set. We have developed an algorithm that, from a user-provided set of variables and parameters or functions of them assumed to be measurable or known, determines all subsets that when used as outputs give a locally structurally identifiable system and are such that any output set for which the system is structurally identifiable must contain at least one of the calculated subsets. The algorithm has been implemented in Mathematica and shown to be feasible and efficient. We have successfully applied it in the analysis of large signalling pathway models from the literature. Copyright © 2012 Elsevier Inc. All rights reserved.

  11. Identifying high-risk medication

    DEFF Research Database (Denmark)

    Sædder, Eva; Brock, Birgitte; Nielsen, Lars Peter


    salicylic acid, and beta-blockers; 30 drugs or drug classes caused 82 % of all serious MEs. The top ten drugs involved in fatal events accounted for 73 % of all drugs identified. CONCLUSION: Increasing focus on seven drugs/drug classes can potentially reduce hospitalizations, extended hospitalizations...

  12. SNP interaction pattern identifier (SIPI)

    DEFF Research Database (Denmark)

    Lin, Hui Yi; Chen, Dung Tsa; Huang, Po Yu


    Motivation: Testing SNP-SNP interactions is considered as a key for overcoming bottlenecks of genetic association studies. However, related statistical methods for testing SNP-SNP interactions are underdeveloped. Results: We propose the SNP Interaction Pattern Identifier (SIPI), which tests 45 bi...

  13. Distributed Persistent Identifiers System Design

    Directory of Open Access Journals (Sweden)

    Pavel Golodoniuc


    Full Text Available The need to identify both digital and physical objects is ubiquitous in our society. Past and present persistent identifier (PID systems, of which there is a great variety in terms of technical and social implementation, have evolved with the advent of the Internet, which has allowed for globally unique and globally resolvable identifiers. PID systems have, by in large, catered for identifier uniqueness, integrity, and persistence, regardless of the identifier’s application domain. Trustworthiness of these systems has been measured by the criteria first defined by Bütikofer (2009 and further elaborated by Golodoniuc 'et al'. (2016 and Car 'et al'. (2017. Since many PID systems have been largely conceived and developed by a single organisation they faced challenges for widespread adoption and, most importantly, the ability to survive change of technology. We believe that a cause of PID systems that were once successful fading away is the centralisation of support infrastructure – both organisational and computing and data storage systems. In this paper, we propose a PID system design that implements the pillars of a trustworthy system – ensuring identifiers’ independence of any particular technology or organisation, implementation of core PID system functions, separation from data delivery, and enabling the system to adapt for future change. We propose decentralisation at all levels — persistent identifiers and information objects registration, resolution, and data delivery — using Distributed Hash Tables and traditional peer-to-peer networks with information replication and caching mechanisms, thus eliminating the need for a central PID data store. This will increase overall system fault tolerance thus ensuring its trustworthiness. We also discuss important aspects of the distributed system’s governance, such as the notion of the authoritative source and data integrity

  14. ORCID: Author Identifiers for Librarians

    Directory of Open Access Journals (Sweden)

    Robyn B. Reed


    Full Text Available Generating accurate publication lists by researchers can be challenging when faced with scholars who have common names or who have published under name variations. This article describes ORCID and the goal of generating author identifiers for scholars to connect their research outputs. Included are the reasons for having author identifiers as well as the types of information within individual profiles. This article includes information on how academic libraries are playing a role with ORCID initiatives as well as describing how publishers, institutions, and funders are employing ORCID in their workflows. Highlighted is material on academic institutions in Pennsylvania using ORCID. The purpose of the article is to provide an overview of ORCID and its uses to inform librarians about this important initiative.

  15. Identifying patient risks during hospitalization

    Directory of Open Access Journals (Sweden)

    Lucélia Ferreira Lima


    Full Text Available Objective: To identify the risks reported at a public institution andto know the main patient risks from the nursing staff point of view.Methods: A retrospective, descriptive and exploratory study. Thesurvey was developed at a hospital in the city of Taboão da Serra, SãoPaulo, Brazil. The study included all nurses working in care areas whoagreed to participate in the study. At the same time, sentinel eventsoccurring in the period from July 2006 to July 2007 were identified.Results: There were 440 sentinel events reported, and the main risksincluded patient falls, medication errors and pressure ulcers. Sixty-fivenurses were interviewed. They also reported patient falls, medicationerrors and pressure ulcers as the main risks. Conclusions: Riskassessment and implementation of effective preventive actions arenecessary to ensure patient’s safety. Involvement of a multidisciplinaryteam is one of the steps for a successful process.

  16. Identifying vertex covers in graphs

    DEFF Research Database (Denmark)

    Henning, Michael A.; Yeo, Anders


    An identifying vertex cover in a graph G is a subset T of vertices in G that has a nonempty intersection with every edge of G such that T distinguishes the edges, that is, e∩T ≠ 0 for every edge e in G and e∩T ≠ f∩T for every two distinct edges e and f in G. The identifying vertex cover number TD......(G) of G is the minimum size of an identifying vertex cover in G. We observe that TD(G)+ρ(G) = |V (G)|, where ρ(G) denotes the packing number of G. We conjecture that if G is a graph of order n and size m with maximum degree Δ, then TD(G) ≤(Δ(Δ-1)/ Δ2+1)n + (2/Δ2+1) m. If the conjecture is true......, then the bound is best possible for all Δ ≥ 1. We prove this conjecture when Δ ≥ 1 and G is a Δ-regular graph. The three known Moore graphs of diameter 2, namely the 5-cycle, the Petersen graph and the Hoffman-Singleton graph, are examples of regular graphs that achieves equality in the upper bound. We also...

  17. Memory outcomes following cognitive interventions in children with neurological deficits: A review with a focus on under-studied populations. (United States)

    Schaffer, Yael; Geva, Ronny


    Given the primary role of memory in children's learning and well-being, the aim of this review was to examine the outcomes of memory remediation interventions in children with neurological deficits as a function of the affected memory system and intervention method. Fifty-seven studies that evaluated the outcome of memory interventions in children were identified. Thirty-four studies met the inclusion criteria, and were included in a systematic review. Diverse rehabilitation methods for improving explicit and implicit memory in children were reviewed. The analysis indicates that teaching restoration strategies may improve, and result in the generalisation of, semantic memory and working memory performance in children older than 7 years with mild to moderate memory deficits. Factors such as longer protocols, emotional support, and personal feedback contribute to intervention efficacy. In addition, the use of compensation aids seems to be highly effective in prospective memory tasks. Finally, the review unveiled a lack of studies with young children and the absence of group interventions. These findings point to the importance of future evidence-based intervention protocols in these areas.

  18. Identifying flares in rheumatoid arthritis

    DEFF Research Database (Denmark)

    Bykerk, Vivian P; Bingham, Clifton O; Choy, Ernest H


    to flare, with escalation planned in 61%. CONCLUSIONS: Flares are common in rheumatoid arthritis (RA) and are often preceded by treatment reductions. Patient/MD/DAS agreement of flare status is highest in patients worsening from R/LDA. OMERACT RA flare questions can discriminate between patients with...... Set. METHODS: Candidate flare questions and legacy measures were administered at consecutive visits to Canadian Early Arthritis Cohort (CATCH) patients between November 2011 and November 2014. The American College of Rheumatology (ACR) core set indicators were recorded. Concordance to identify flares...


    Directory of Open Access Journals (Sweden)

    Răducu Marian PETRESCU


    Full Text Available This work aims to identify and develop best practices in the insurance field. We must mention from the beginning that best practices are not compulsory or mandatory rules of law, they cannot and do not want to be placed above the legal provisions in force, they only complement the law. Moreover, we intend to look into the implementation of the Solvency II Directive from the point of view of best practices in insurance. In this research, the main method of study was the theoretical qualitative research (especially document analysis, with the purpose to identify and theoretically develop the information on best practices in the insurance field. The main results of the research consist in the identification of general best practices in performing the activity (such as communication/consultation with the interested parties, the consistency as regards contractual/non-contractual relations, the effectiveness and efficiency, transparency and honesty, fair treatment of customers etc. which have been presented in short and which could be implemented by any company that seeks to achieve superior performances, including the insurance companies. The work also includes some important best practices, described in detail, in a sensitive area such as the insurance field (best practices in relation to the management of personal information, the management and settlement of disputes by insurance companies or intermediaries in the field of insurance etc..

  20. Featured Image: Identifying Weird Galaxies (United States)

    Kohler, Susanna


    Hoags Object, an example of a ring galaxy. [NASA/Hubble Heritage Team/Ray A. Lucas (STScI/AURA)]The above image (click for the full view) shows PanSTARRSobservationsof some of the 185 galaxies identified in a recent study as ring galaxies bizarre and rare irregular galaxies that exhibit stars and gas in a ring around a central nucleus. Ring galaxies could be formed in a number of ways; one theory is that some might form in a galaxy collision when a smaller galaxy punches through the center of a larger one, triggering star formation around the center. In a recent study, Ian Timmis and Lior Shamir of Lawrence Technological University in Michigan explore ways that we may be able to identify ring galaxies in the overwhelming number of images expected from large upcoming surveys. They develop a computer analysis method that automatically finds ring galaxy candidates based on their visual appearance, and they test their approach on the 3 million galaxy images from the first PanSTARRS data release. To see more of the remarkable galaxies the authors found and to learn more about their identification method, check out the paper below.CitationIan Timmis and Lior Shamir 2017 ApJS 231 2. doi:10.3847/1538-4365/aa78a3

  1. Persistent Identifiers as Boundary Objects (United States)

    Parsons, M. A.; Fox, P. A.


    In 1989, Leigh Star and Jim Griesemer defined the seminal concept of `boundary objects'. These `objects' are what Latour calls `immutable mobiles' that enable communication and collaboration across difference by helping meaning to be understood in different contexts. As Star notes, they are a sort of arrangement that allow different groups to work together without (a priori) consensus. Part of the idea is to recognize and allow for the `interpretive flexibility' that is central to much of the `constructivist' approach in the sociology of science. Persistent Identifiers (PIDs) can clearly act as boundary objects, but people do not usually assume that they enable interpretive flexibility. After all, they are meant to be unambiguous, machine-interpretable identifiers of defined artifacts. In this paper, we argue that PIDs can fill at least two roles: 1) That of the standardized form, where there is strong agreement on what is being represented and how and 2) that of the idealized type, a more conceptual concept that allows many different representations. We further argue that these seemingly abstract conceptions actually help us implement PIDs more effectively to link data, publications, various other artifacts, and especially people. Considering PIDs as boundary objects can help us address issues such as what level of granularity is necessary for PIDs, what metadata should be directly associated with PIDs, and what purpose is the PID serving (reference, provenance, credit, etc.). In short, sociological theory can improve data sharing standards and their implementation in a way that enables broad interdisciplinary data sharing and reuse. We will illustrate this with several specific examples of Earth science data.

  2. Identifying and Tracing User Needs (United States)

    To, C.; Tauer, E.


    Providing adequate tools to the user community hinges on reaching the specific goals and needs behind the intended application of the tool. While the approach of leveraging user-supplied inputs and use cases to identify those goals is not new, there frequently remains the challenge of tracing those use cases through to implementation in an efficient and manageable fashion. Processes can become overcomplicated very quickly, and additionally, explicitly mapping progress towards the achievement of the user demands can become overwhelming when hundreds of use-cases are at play. This presentation will discuss a demonstrated use-case approach that has achieved an initial success with a tool re-design and deployment, the means to apply use cases in the generation of a roadmap for future releases over time, and the ability to include and adjust to new user requirements and suggestions with minimal disruption to the traceability. It is hoped that the findings and lessons learned will help make use case employment easier for others seeking to create user-targeted capabilities.

  3. RECOVIR Software for Identifying Viruses (United States)

    Chakravarty, Sugoto; Fox, George E.; Zhu, Dianhui


    Most single-stranded RNA (ssRNA) viruses mutate rapidly to generate a large number of strains with highly divergent capsid sequences. Determining the capsid residues or nucleotides that uniquely characterize these strains is critical in understanding the strain diversity of these viruses. RECOVIR (an acronym for "recognize viruses") software predicts the strains of some ssRNA viruses from their limited sequence data. Novel phylogenetic-tree-based databases of protein or nucleic acid residues that uniquely characterize these virus strains are created. Strains of input virus sequences (partial or complete) are predicted through residue-wise comparisons with the databases. RECOVIR uses unique characterizing residues to identify automatically strains of partial or complete capsid sequences of picorna and caliciviruses, two of the most highly diverse ssRNA virus families. Partition-wise comparisons of the database residues with the corresponding residues of more than 300 complete and partial sequences of these viruses resulted in correct strain identification for all of these sequences. This study shows the feasibility of creating databases of hitherto unknown residues uniquely characterizing the capsid sequences of two of the most highly divergent ssRNA virus families. These databases enable automated strain identification from partial or complete capsid sequences of these human and animal pathogens.

  4. Identifying ELIXIR Core Data Resources. (United States)

    Durinx, Christine; McEntyre, Jo; Appel, Ron; Apweiler, Rolf; Barlow, Mary; Blomberg, Niklas; Cook, Chuck; Gasteiger, Elisabeth; Kim, Jee-Hyub; Lopez, Rodrigo; Redaschi, Nicole; Stockinger, Heinz; Teixeira, Daniel; Valencia, Alfonso


    The core mission of ELIXIR is to build a stable and sustainable infrastructure for biological information across Europe. At the heart of this are the data resources, tools and services that ELIXIR offers to the life-sciences community, providing stable and sustainable access to biological data. ELIXIR aims to ensure that these resources are available long-term and that the life-cycles of these resources are managed such that they support the scientific needs of the life-sciences, including biological research. ELIXIR Core Data Resources are defined as a set of European data resources that are of fundamental importance to the wider life-science community and the long-term preservation of biological data. They are complete collections of generic value to life-science, are considered an authority in their field with respect to one or more characteristics, and show high levels of scientific quality and service. Thus, ELIXIR Core Data Resources are of wide applicability and usage. This paper describes the structures, governance and processes that support the identification and evaluation of ELIXIR Core Data Resources. It identifies key indicators which reflect the essence of the definition of an ELIXIR Core Data Resource and support the promotion of excellence in resource development and operation. It describes the specific indicators in more detail and explains their application within ELIXIR's sustainability strategy and science policy actions, and in capacity building, life-cycle management and technical actions. The identification process is currently being implemented and tested for the first time. The findings and outcome will be evaluated by the ELIXIR Scientific Advisory Board in March 2017. Establishing the portfolio of ELIXIR Core Data Resources and ELIXIR Services is a key priority for ELIXIR and publicly marks the transition towards a cohesive infrastructure.

  5. Psychosocial counselling of identifiable sperm donors

    NARCIS (Netherlands)

    Visser, M.; Mochtar, M.H.; de Melker, A.A.; van der Veen, F.; Repping, S.; Gerrits, T.


    STUDY QUESTION: What do identifiable sperm donors feel about psychosocial counselling? SUMMARY ANSWER: Identifiable sperm donors found it important that psychosocial counselling focused on emotional consequences and on rules and regulations and they expected to have access to psychosocial

  6. Psychosocial counselling of identifiable sperm donors

    NARCIS (Netherlands)

    Visser, M. [=Marja; Mochtar, M. H.; de Melker, A. A.; van der Veen, F.; Repping, S.; Gerrits, T.


    What do identifiable sperm donors feel about psychosocial counselling? Identifiable sperm donors found it important that psychosocial counselling focused on emotional consequences and on rules and regulations and they expected to have access to psychosocial counselling at the time that

  7. Method of identifying plant pathogen tolerance (United States)

    Ecker, J.R.; Staskawicz, B.J.; Bent, A.F.; Innes, R.W.


    A process for identifying a plant having disease tolerance comprising administering to a plant an inhibitory amount of ethylene and screening for ethylene insensitivity, thereby identifying a disease tolerant plant, is described. Plants identified by the foregoing process are also described. 7 figs.

  8. A probabilistic perspective on re-identifiability

    NARCIS (Netherlands)

    Koot, M.; Mandjes, M.; van 't Noordende, G.; de Laat, C.


    A quasi-identifier is a set of attributes that can be used to re-identify entries in anonymized data sets. A group of individuals is considered about whom quasi-identifying numerical information is disclosed such as date of birth, age, weight, and height. The fraction of individuals is determined

  9. Ability of Slovakian Pupils to Identify Birds (United States)

    Prokop, Pavol; Rodak, Rastislav


    A pupil's ability to identify common organisms is necessary for acquiring further knowledge of biology. We investigated how pupils were able to identify 25 bird species following their song, growth habits, or both features presented simultaneously. Just about 19% of birds were successfully identified by song, about 39% by growth habit, and 45% of…

  10. The challenge of measuring investments and identifying investors

    DEFF Research Database (Denmark)

    Christensen, Jesper Lindgaard; Hain, Daniel S.


    , there are several types of flaws and difficulties related to getting a statistical overview of investments in innovation in the energy sector; it is not just a matter of increasing the existing statistical efforts and precision, there are more generic difficulties. Obviously, activity indicators of energy...... innovation (cf. other chapters in this volume) are closely related to indicators of investments in energy innovation. Hence, a number of general measurement challenges, such as separating innovation and activities, apply to investment measurement as well. Furthermore, any kinds of outcome measures...... in the energy realm, and elsewhere, are by nature interdependent with investment activities. We will in this chapter focus on the challenges that are special to the investment activities and on the mapping of investors. The measurement challenges may be approached from a ‘receiver’ perspective, i...

  11. Robotic anesthesia: not the realm of science fiction any more. (United States)

    Hemmerling, Thomas M; Terrasini, Nora


    Robots are present in surgery, to a much lesser extent in the field of anesthesia. The purpose of this review is to show the latest and most important findings in robotic anesthesia. Moreover, this review argues the importance and utility of robots in anesthesia. Over the years, many closed-loop systems have been developed; they were able to control only one or two of the three components of anesthesia: hypnosis, analgesia, or muscle relaxation. McSleepy controls all three components of anesthesia, from induction to emergence of anesthesia. Telemedical applications have not only led to remote monitoring but even to remotely controlled anesthesia, such as transcontinental anesthesia. A new closed-loop system for sedation, called Sedasys, could revolutionize the field of nonoperating room sedation. 'Manual robots' are used to help and replace anesthesiologists performing anesthesia procedures. Specific robots for intubation and nerve blocks have been developed and tested in humans. Robots can improve performance in anesthesia and healthcare. Closed-loop systems are the basis for pharmacological robots. Safe anesthetic care might be delivered through teleanesthesia whenever qualified personnel are not available or need support. Mechanical robots are being developed for anesthesia care.

  12. Safeguards needs in the measurement area: the realm of measurements

    International Nuclear Information System (INIS)

    Hammond, G.; Auerbach, C.


    An effective safeguards measurement system must cover a multitude of material forms ranging from essentially pure substances to highly heterogeneous materials. In addition there are varied and sometimes conflicting demands for accuracy and timeliness. Consequently, a judicious and systematic choice must be made between methods based on sampling followed by chemical analysis or nondestructive methods based on nuclear properties. Fundamental advances in analytical chemistry made during the year preceding World War II enabled Manhattan Project scientists to develop methods which contributed to the success of both the immediate goal and the developments which have taken place since. Examples are given of evolutionary developments in the direction of timeliness through varying degrees of automation. Nondestructive methods, first introduced because of the need to measure scrap and other intractable material, are finding broader areas of application. Aided by DOE-sponsored research and development, new techniques providing greater accuracy, versatility and timeliness are being introduced. It is now recognized that an effective safeguards measurement system must make concerted use of both chemical and nondestructive methods. Recent studies have fostered understanding of the relative importance of various process streams in the material balance equations and have highlighted the need for a systematic approach to measurement solutions for safeguarding nuclear materials

  13. Teaching Art in the Neoliberal Realm : Realism versus Cynicism

    NARCIS (Netherlands)

    Gielen, Pascal


    In most countries art education is not immune from a large-scale reorganisation. Educational institutions are increasingly required to operate as enterprises that compete for the best or the largest number of students and to express their objective and results in financial and management terms. In

  14. Invisible waves and hidden realms: augmented reality and experimental art (United States)

    Ruzanka, Silvia


    Augmented reality is way of both altering the visible and revealing the invisible. It offers new opportunities for artistic exploration through virtual interventions in real space. In this paper, the author describes the implementation of two art installations using different AR technologies, one using optical marker tracking on mobile devices and one integrating stereoscopic projections into the physical environment. The first artwork, De Ondas y Abejas (The Waves and the Bees), is based on the widely publicized (but unproven) hypothesis of a link between cellphone radiation and the phenomenon of bee colony collapse disorder. Using an Android tablet, viewers search out small fiducial markers in the shape of electromagnetic waves hidden throughout the gallery, which reveal swarms of bees scattered on the floor. The piece also creates a generative soundscape based on electromagnetic fields. The second artwork, Urban Fauna, is a series of animations in which features of the urban landscape become plants and animals. Surveillance cameras become flocks of birds while miniature cellphone towers, lampposts, and telephone poles grow like small seedlings in time-lapse animation. The animations are presented as small stereoscopic projections, integrated into the physical space of the gallery. These two pieces explore the relationship between nature and technology through the visualization of invisible forces and hidden alternate realities.

  15. Sloppiness and Distinctness in the Realm of Body language

    DEFF Research Database (Denmark)

    Juel Henrichsen, Peter


    Based on eight video recordings of people meeting for the first time we ex-plore how the degree of explicitness "in body language", or gesturing, cor-relates with the communicated attitude (as perceived by annotators). We also discuss the significance of such investigations for the design and de...

  16. Refracted subject: sexualness in the realms of law and epidemiology


    Khanna, Akshay


    There are many ways in which gender diversity and sexualness are experienced, spoken of and transacted in India. Recent activism against marginalisation related to sexual and gender nonconformity has led to transformation of some of these idioms into objects that circulate in particular registers of governmentality. In the process, something quite else is created, and this something else portends to speak the truth of 'sexuality in India'. Based on fieldwork carried out between 20...

  17. Understanding the role of organizational legitimacy within the realm ...

    African Journals Online (AJOL)

    CBC) strategies to incorporate rural communities into conservation efforts. One key component to the success of these strategies is to gain trust within the communities which reside in the vicinity of the targeted areas for conservation.

  18. Changing climate and microbial resources in polar realms

    Digital Repository Service at National Institute of Oceanography (India)

    LokaBharathi, P.A.

    relationship that exists between oceanic primayy productivity and sea surface OMS concentrations and justifies more intense observations on a dynamcc scale . Besides contributing to climate modulating processe,, microbial metabolites could contribute to a... | 49 SaGAA 2011 Antifreeze proteins have been used from microbial sources and higher organisms for processing low fat food items like ice cream. Such proteins can also be used to improve surgery and tissue transplants. Plants could also be engineered...

  19. Spiritual Quest in the Realm of Harry Potter. (United States)

    Radley, Gail


    Looks at the alternate and fantastic world of Harry Potter because it has so captured the imaginations of children and adults alike, garnering unprecedented weeks on the New York Times bestseller list. Describes many specific examples in which readers can connect and relate to the Harry Potter books. (SG)

  20. Geophysical and geodynamic studies of the North Atlantic Realm

    DEFF Research Database (Denmark)

    Schiffer, Christian


    on the rift evolution and passive margin formation, especially because eclogite and serpentinite are “weaker” materials, and therefore could localise extension of the lithosphere. Numerical modelling shows that a fossil subduction complex, together with variations in crustal thickness and extension rate have......, the supercontinent-cycle and the plume theory. In general, the major elements of the geological evolution in this region during the past 450 Ma are understood. However, the crucial details of this evolution are the subject of much discussion and include the following items: a) The formation of the Caledonian...... Fjord (CF) region, overlain by a zone of considerably low mantle velocities. This distinct signature is interpreted as a fossil subduction zone of Caledonian age, with a slab of eclogitised mafic crust as well as a hydrated and partly serpentinised mantle wedge. Manuscripts P3 and P4 are inspired...

  1. Some algebraically topological aspects in the realm of convenient ...

    African Journals Online (AJOL)

    A cohomology theory for filter spaces is developed in such a way that a suitable variant of the Eilenberg-Steenrod axioms is satisfied. Furthermore, path connectedness and fundamental groups are generalized to limit spaces. Quaestiones Mathematicae 23(2000), 99–112 ...

  2. Sustainable Energy Landscape: Implementing Energy Transition in the Physical Realm

    NARCIS (Netherlands)

    Stremke, S.


    Since the beginning of the new millennium, the concept of “energy landscape” is being discussed by academia from the environmental design domain while more and more practitioners have been contributing to sustainable energy transition. Yet, there remains some ambiguity as to what exactly is meant

  3. Digital terrain modeling and industrial surface metrology: Converging realms (United States)

    Pike, R.J.


    Digital terrain modeling has a micro-and nanoscale counterpart in surface metrology, the numerical characterization of industrial surfaces. Instrumentation in semiconductor manufacturing and other high-technology fields can now contour surface irregularities down to the atomic scale. Surface metrology has been revolutionized by its ability to manipulate square-grid height matrices that are analogous to the digital elevation models (DEMs) used in physical geography. Because the shaping of industrial surfaces is a spatial process, the same concepts of analytical cartography that represent ground-surface form in geography evolved independently in metrology: The surface topography of manufactured components, exemplified here by automobile-engine cylinders, is routinely modeled by variogram analysis, relief shading, and most other techniques of parameterization and visualization familiar to geography. This article introduces industrial surface-metrology, examines the field in the context of terrain modeling and geomorphology and notes their similarities and differences, and raises theoretical issues to be addressed in progressing toward a unified practice of surface morphometry.

  4. Exploring the Meta-Pragmatic Realm in English Language Teaching (United States)

    McConachy, Troy


    As the speakership of English worldwide continues to grow, English language teachers are required to devise ways to prepare their learners for communicating successfully across cultures. As pragmatics is particularly tied up with culture, the ways in which individuals from different cultures will orient to pragmatic phenomena in their interaction…

  5. Applying systems engineering methodologies to the micro- and nanoscale realm (United States)

    Garrison Darrin, M. Ann


    Micro scale and nano scale technology developments have the potential to revolutionize smart and small systems. The application of systems engineering methodologies that integrate standalone, small-scale technologies and interface them with macro technologies to build useful systems is critical to realizing the potential of these technologies. This paper covers the expanding knowledge base on systems engineering principles for micro and nano technology integration starting with a discussion of the drivers for applying a systems approach. Technology development on the micro and nano scale has transition from laboratory curiosity to the realization of products in the health, automotive, aerospace, communication, and numerous other arenas. This paper focuses on the maturity (or lack thereof) of the field of nanosystems which is emerging in a third generation having transitioned from completing active structures to creating systems. The emphasis of applying a systems approach focuses on successful technology development based on the lack of maturity of current nano scale systems. Therefore the discussion includes details relating to enabling roles such as product systems engineering and technology development. Classical roles such as acquisition systems engineering are not covered. The results are also targeted towards small-scale technology developers who need to take into account systems engineering processes such as requirements definition, verification, and validation interface management and risk management in the concept phase of technology development to maximize the likelihood of success, cost effective micro and nano technology to increase the capability of emerging deployed systems and long-term growth and profits.

  6. New Motifs in Deoxydehydration: Beyond the Realms of Rhenium

    DEFF Research Database (Denmark)

    Petersen, Allan Robertson; Fristrup, Peter


    The deoxydehydration (DODH) reaction remains one of the most efficient methods of reducing the oxygen content of biomass while keeping important functionality in place. This reaction is traditionally catalysed by high-valent oxo-rhenium species. Recent research into heterogeneous rhenium-based ca...

  7. The Paradox of the Public Realm in Richard Rorty

    Directory of Open Access Journals (Sweden)

    Martha Palacio Avendaño


    Full Text Available The concepto of the public sphere in Richard Rorty's philosophy, inherited of liberal tradition, allows be treated as a part of a game of language called democratic liberalism. One of the rules for validating a move in this game consists in taking for granted the distinction between the public and the private spheres. Richard Rorty thought that democratic liberalism did not need any foundation beyond the way to play it; its only criteria would be the game's practices, according an utopia which would allow us to make more movements in the game. That is, democratic liberalism does not require foundations, but just practices for achieving a social hioe inspired on freedom and pluralism. This kind of utopia, based upon the non-cruelty principle, would make possible an inclusive society where everyone would have a place for their own private vocabulary. In this way, Rorty would have linked freedom and solidarity. However, this language-game reveals the paradox of the link which implies the meaning of the public shere. Herein, freedom is not a sufficient condition of solidarity; hence, there is no place for social inclusion in Rorty's language game.

  8. Geophysical and geodynamic studies of the North Atlantic Realm

    DEFF Research Database (Denmark)

    Schiffer, Christian


    by the Department of Geoscience, Aarhus University for period of 2 years. The results are summarised in two manuscripts, describing receiver function analysis as well as gravity and petrological modelling (P1 and P2). These studies reveal an east-dipping high velocity structure in the upper mantle of the Central...... on the rift evolution and passive margin formation, especially because eclogite and serpentinite are “weaker” materials, and therefore could localise extension of the lithosphere. Numerical modelling shows that a fossil subduction complex, together with variations in crustal thickness and extension rate have...

  9. Vibrant architecture material realm as a codesigner of living spaces

    CERN Document Server

    Armstrong, Rachel


    This book sets out the conditions in which the need for a new approach to the production of architecture in the twenty-first century is established, where our homes and cities are facing increasing pressures from environmental challenges that are compromising our well being and our lives. Vibrant architecture embodies a new kind of architectural design practice that explores how lively materials, or ‘vibrant matter’ may be incorporated into our buildings to confer on them some of the properties of living things such as, movement, growth, sensitivity and self-repair. My research examines the theoretical and practical implications of how this may occur through the application of a new group of materials in the production of our living spaces, collectively referred to as ‘vibrant matter’.

  10. Fundamental Questions of Practical Cosmology Exploring the Realm of Galaxies

    CERN Document Server

    Baryshev, Yurij


    This book guides readers (astronomers, physicists, and university students) through central questions of Practical Cosmology, a term used by the late Allan Sandage to denote the modern scientific endeavor to find the cosmological model best describing the universe of galaxies, its geometry, size, age, and matter composition. The authors draw on their personal experience in astrophysics and cosmology to explain key concepts of cosmology, both observational and theoretical, and to highlight several items which give cosmology its special character. These highlighted items are: - Idiosyncratic features of the “cosmic laboratory” - Malmquist bias in the determination of cosmic distances - Theory of gravitation as a cornerstone of cosmological models - Crucial tests for checking the reality of space expansion - Methods of analyzing the structures of the universe as mapped by galaxies -  Usefulness of fractals as a model to describe the large-scale structure - New cosmological physics inherent in the Frie...

  11. On the Third Realm--Pedagogue Pride: Notes on Professionalism. (United States)

    Smith, Ralph A.


    There are two potential dangers flowing from current educational criticism: deschooling and deprofessionalization. Whether these two dangers are imminent or remote so far as schooling in general is concerned, they are immediate and pressing for the profession of art and aesthetic education. (Author)

  12. Integrable systems in the realm of algebraic geometry

    CERN Document Server

    Vanhaecke, Pol


    This book treats the general theory of Poisson structures and integrable systems on affine varieties in a systematic way. Special attention is drawn to algebraic completely integrable systems. Several integrable systems are constructed and studied in detail and a few applications of integrable systems to algebraic geometry are worked out. In the second edition some of the concepts in Poisson geometry are clarified by introducting Poisson cohomology; the Mumford systems are constructed from the algebra of pseudo-differential operators, which clarifies their origin; a new explanation of the multi Hamiltonian structure of the Mumford systems is given by using the loop algebra of sl(2); and finally Goedesic flow on SO(4) is added to illustrate the linearizatin algorith and to give another application of integrable systems to algebraic geometry.

  13. Political battle drifts into pensioners' realm / Talis Saule Archdeacon

    Index Scriptorium Estoniae

    Archdeacon, Talis Saule


    Läti endised ministrid lõid poliitilise organisatsiooni, mis korraldab referendumi Läti madala vanaduspensioni tõstmise toetuseks. Samas valmistub ka valitsus pensionite tõstmiseks. Lisa: Faktid pensioni ja pensionäride kohta Lätis

  14. Sustainable development and its evolution in the realm of ...

    African Journals Online (AJOL)

    Sustainable development has become a term of recurrent use by governments, policy makers, academics and environmental activists. It denotes a process of human development through which resources are used to meet human needs while preserving the quality of natural environment and the objective of which is to ...

  15. 29 CFR 4010.7 - Identifying information. (United States)


    ... 29 Labor 9 2010-07-01 2010-07-01 false Identifying information. 4010.7 Section 4010.7 Labor Regulations Relating to Labor (Continued) PENSION BENEFIT GUARANTY CORPORATION CERTAIN REPORTING AND DISCLOSURE REQUIREMENTS ANNUAL FINANCIAL AND ACTUARIAL INFORMATION REPORTING § 4010.7 Identifying information...

  16. Water resources management in Tanzania: identifying research ...

    African Journals Online (AJOL)

    This paper aims at identifying research gaps and needs and recommendations for a research agenda on water resources management in Tanzania. We reviewed published literature on water resources management in Tanzania in order to highlight what is currently known, and to identify knowledge gaps, and suggest ...

  17. Identifying Needs and Opportunities for Local Government ...

    African Journals Online (AJOL)

    required for better environmental management and the establishment of education and training processes for .... The Education and Training Practices Project (NTB, 1998) identified important links between Applied ... to learn directly from departmental staff what education and training needs they identified with regard to ...

  18. Moving Beyond Weak Identifiers for Proxemic Interaction

    DEFF Research Database (Denmark)

    Sørensen, Henrik; Kjeldskov, Jesper


    is significantly closer than what is actually the case. This makes the smartphone a weak identifier for applications that need to track persons. With a focus on feasible interaction design, we present a concept and prototype of a platform, which seek to support proxemic interaction beyond weak identifiers...

  19. Learning environments matter: Identifying influences on the ...

    African Journals Online (AJOL)


    The students completed the Student Motivation for Science Learning questionnaire. Significant differences were identified between different groups and school types. The study is important for identifying the key role of achievement goals, science learning values and science self-efficacies. The main finding emphasises the.


    Directory of Open Access Journals (Sweden)



    Full Text Available Review of history matching of reservoirs parameters in groundwater flow raises the problem of identifiability of aquifer systems. Lack of identifiability means that there exists parameters to which the heads are insensitive. From the guidelines of the study of the homogeneous case, we inspect the identifiability of the distributed transmissivity field of heterogeneous groundwater aquifers. These are derived from multiple realizations of a random function Y = log T  whose probability distribution function is normal. We follow the identifiability of the autocorrelated block transmissivities through the measure of the sensitivity of the local derivatives DTh = (∂hi  ∕ ∂Tj computed for each sample of a population N (0; σY, αY. Results obtained from an analysis of Monte Carlo type suggest that the more a system is heterogeneous, the less it is identifiable.

  1. EZID: Long term identifiers made easy (Invited) (United States)

    Starr, J.


    Scholarly research is producing ever increasing amounts of digital research data, and this data should be managed throughout the research life cycle both as part of good scientific practice, but also to comply with funder mandates, such as the 2013 OSTP Public Access Memo ( By assigning unique and persistent identifiers to data objects, data managers can gain control and flexibility over what can be a daunting task. This is due to the fact that the objects can be moved to new locations without disruption to links, as long as the identifier target is maintained. EZID is a tool that makes assigning and maintaining unique, persistent identifiers easy. It was designed and built by California Digital Library (CDL) and has both a user interface and a RESTful API. EZID currently offers services for two globally unique, persistent identifier schemes: Digital Object Identifiers (DOIs) and Archival Resource Keys (ARKs). DOIs are identifiers originating from the publishing world and are in widespread use for journal articles. CDL is able to offer DOIs because of being a founding member of DataCite (, an international consortium established to provide easier access to scientific research data on the Internet. ARKs are identifiers originating from the library, archive and museum community. Like DOIs, they become persistent when the objects and identifier forwarding information is maintained. DOIs and ARKs have a key role in data management and, therefore, in data management plans. DOIs are the recommended identifier for use in data citation, and ARKs provide the maximum flexibility needed for data documentation and management throughout the early phases of a project. The two identifier schemes are able to be used together, and EZID is made to work with both. EZID clients, coming from education, research, government, and the private sector, are utilizing the

  2. A simplified method to assess structurally identifiable parameters in Monod-based activated sludge models. (United States)

    Petersen, Britta; Gernaey, Krist; Devisscher, Martijn; Dochain, Denis; Vanrolleghem, Peter A


    The first step in the estimation of parameters of models applied for data interpretation should always be an investigation of the identifiability of the model parameters. In this study the structural identifiability of the model parameters of Monod-based activated sludge models (ASM) was studied. In an illustrative example it was assumed that respirometric (dissolved oxygen or oxygen uptake rates) and titrimetric (cumulative proton production) measurements were available for the characterisation of nitrification. Two model structures, including the presence and absence of significant growth for description of long- and short-term experiments, respectively, were considered. The structural identifiability was studied via the series expansion methods. It was proven that the autotrophic yield becomes uniquely identifiable when combined respirometric and titrimetric data are assumed for the characterisation of nitrification. The most remarkable result of the study was, however, that the identifiability results could be generalised by applying a set of ASM1 matrix based generalisation rules. It appeared that the identifiable parameter combinations could be predicted directly based on the knowledge of the process model under study (in ASM1-like matrix representation), the measured variables and the biodegradable substrate considered. This generalisation reduces the time-consuming task of deriving the structurally identifiable model parameters significantly and helps the user to obtain these directly without the necessity to go too deeply into the mathematical background of structural identifiability.

  3. Communicating identifiability risks to biobank donors

    DEFF Research Database (Denmark)

    Kasperbauer, T. J.; Gjerris, Mickey; Waldemar, Gunhild


    can track individuals across multiple databases. This article focuses on the communication of identifiability risks in the process of obtaining consent for donation and research. Most ethical discussions of identifiability risks have focused on the severity of the risk and how it might be mitigated......, and what precisely is at stake in pervasive data sharing. However, there has been little discussion of whether and how to communicate the risk to potential donors. We review the ethical arguments behind favoring different types of risk communication in the consent process, and outline how identifiability...... concerns can be incorporated into either a detailed or a simplified method of communicating risks during the consent process....

  4. Identifying Codes on Directed De Bruijn Graphs (United States)


    JOURNAL ARTICLE (POST PRINT) 3. DATES COVERED (From - To) JUN 2013 – AUG 2015 4. TITLE AND SUBTITLE IDENTIFYING CODES ON DIRECTED DE BRUIJN GRAPHS 5a...owner. 14. ABSTRACT For a directed graph G, a t-identifying code is a subset S ⊆ V (G) with the property that for each vertex v ∈ V (G) the set of...vertices of S reachable from v by a directed path of length at most t is both non-empty and unique. A graph is called t- identifiable if there exists a

  5. Helping You Identify Quality Laboratory Services (United States)

    Helping You Identify Quality Laboratory Services Selecting quality health care services for yourself, a relative or friend requires special thought and attention. The Joint Commission has prepared this information ...

  6. Identifiable Data Files - Health Outcomes Survey (HOS) (United States)

    U.S. Department of Health & Human Services — The Medicare Health Outcomes Survey (HOS) identifiable data files are comprised of the entire national sample for a given 2-year cohort (including both respondents...

  7. Identifying significant environmental features using feature recognition. (United States)


    The Department of Environmental Analysis at the Kentucky Transportation Cabinet has expressed an interest in feature-recognition capability because it may help analysts identify environmentally sensitive features in the landscape, : including those r...

  8. NIH Researchers Identify OCD Risk Gene (United States)

    ... Issues Research News From NIH NIH Researchers Identify OCD Risk Gene Past Issues / Summer 2006 Table of ... gene variant that doubles an individual's risk for obsessive-compulsive disorder (OCD). The new functional variant, or allele, is ...

  9. ORCID Author Identifiers: A Primer for Librarians. (United States)

    Akers, Katherine G; Sarkozy, Alexandra; Wu, Wendy; Slyman, Alison


    The ORCID (Open Researcher and Contributor ID) registry helps disambiguate authors and streamline research workflows by assigning unique 16-digit author identifiers that enable automatic linkages between researchers and their scholarly activities. This article describes how ORCID works, the benefits of using ORCID, and how librarians can promote ORCID at their institutions by raising awareness of ORCID, helping researchers create and populate ORCID profiles, and integrating ORCID identifiers into institutional repositories and other university research information systems.

  10. OCRWM baseline management procedure for document identifiers

    International Nuclear Information System (INIS)


    This procedure establishes a uniform numbering system (document identifier) for all Program and project technical, cost, and schedule baselines, and selected management and procurement documents developed for and controlled by the Office of Civilian Radioactive Waste Management (OCRWM) for the Civilian Radioactive Waste Management System (CRWMS). The document identifier defined in this procedure is structured to ensure that the relational integrity between configuration items (CIs) and their associated documentation and software is maintained, traceable, categorical, and retrievable for the life of the program

  11. Exploiting intrinsic fluctuations to identify model parameters. (United States)

    Zimmer, Christoph; Sahle, Sven; Pahle, Jürgen


    Parameterisation of kinetic models plays a central role in computational systems biology. Besides the lack of experimental data of high enough quality, some of the biggest challenges here are identification issues. Model parameters can be structurally non-identifiable because of functional relationships. Noise in measured data is usually considered to be a nuisance for parameter estimation. However, it turns out that intrinsic fluctuations in particle numbers can make parameters identifiable that were previously non-identifiable. The authors present a method to identify model parameters that are structurally non-identifiable in a deterministic framework. The method takes time course recordings of biochemical systems in steady state or transient state as input. Often a functional relationship between parameters presents itself by a one-dimensional manifold in parameter space containing parameter sets of optimal goodness. Although the system's behaviour cannot be distinguished on this manifold in a deterministic framework it might be distinguishable in a stochastic modelling framework. Their method exploits this by using an objective function that includes a measure for fluctuations in particle numbers. They show on three example models, immigration-death, gene expression and Epo-EpoReceptor interaction, that this resolves the non-identifiability even in the case of measurement noise with known amplitude. The method is applied to partially observed recordings of biochemical systems with measurement noise. It is simple to implement and it is usually very fast to compute. This optimisation can be realised in a classical or Bayesian fashion.


    International Nuclear Information System (INIS)

    Marcus, Robert A.; Ragozzine, Darin; Murray-Clay, Ruth A.; Holman, Matthew J.


    The identification and characterization of numerous collisional families-clusters of bodies with a common collisional origin-in the asteroid belt has added greatly to the understanding of asteroid belt formation and evolution. More recent study has also led to an appreciation of physical processes that had previously been neglected (e.g., the Yarkovsky effect). Collisions have certainly played an important role in the evolution of the Kuiper Belt as well, though only one collisional family has been identified in that region to date, around the dwarf planet Haumea. In this paper, we combine insights into collisional families from numerical simulations with the current observational constraints on the dynamical structure of the Kuiper Belt to investigate the ideal sizes and locations for identifying collisional families. We find that larger progenitors (r ∼ 500 km) result in more easily identifiable families, given the difficulty in identifying fragments of smaller progenitors in magnitude-limited surveys, despite their larger spread and less frequent occurrence. However, even these families do not stand out well from the background. Identifying families as statistical overdensities is much easier than characterizing families by distinguishing individual members from interlopers. Such identification seems promising, provided the background population is well known. In either case, families will also be much easier to study where the background population is small, i.e., at high inclinations. Overall, our results indicate that entirely different techniques for identifying families will be needed for the Kuiper Belt, and we provide some suggestions.

  13. Distributed design approach in persistent identifiers systems (United States)

    Golodoniuc, Pavel; Car, Nicholas; Klump, Jens


    The need to identify both digital and physical objects is ubiquitous in our society. Past and present persistent identifier (PID) systems, of which there is a great variety in terms of technical and social implementations, have evolved with the advent of the Internet, which has allowed for globally unique and globally resolvable identifiers. PID systems have catered for identifier uniqueness, integrity, persistence, and trustworthiness, regardless of the identifier's application domain, the scope of which has expanded significantly in the past two decades. Since many PID systems have been largely conceived and developed by small communities, or even a single organisation, they have faced challenges in gaining widespread adoption and, most importantly, the ability to survive change of technology. This has left a legacy of identifiers that still exist and are being used but which have lost their resolution service. We believe that one of the causes of once successful PID systems fading is their reliance on a centralised technical infrastructure or a governing authority. Golodoniuc et al. (2016) proposed an approach to the development of PID systems that combines the use of (a) the Handle system, as a distributed system for the registration and first-degree resolution of persistent identifiers, and (b) the PID Service (Golodoniuc et al., 2015), to enable fine-grained resolution to different information object representations. The proposed approach solved the problem of guaranteed first-degree resolution of identifiers, but left fine-grained resolution and information delivery under the control of a single authoritative source, posing risk to the long-term availability of information resources. Herein, we develop these approaches further and explore the potential of large-scale decentralisation at all levels: (i) persistent identifiers and information resources registration; (ii) identifier resolution; and (iii) data delivery. To achieve large-scale decentralisation

  14. Scalable persistent identifier systems for dynamic datasets (United States)

    Golodoniuc, P.; Cox, S. J. D.; Klump, J. F.


    Reliable and persistent identification of objects, whether tangible or not, is essential in information management. Many Internet-based systems have been developed to identify digital data objects, e.g., PURL, LSID, Handle, ARK. These were largely designed for identification of static digital objects. The amount of data made available online has grown exponentially over the last two decades and fine-grained identification of dynamically generated data objects within large datasets using conventional systems (e.g., PURL) has become impractical. We have compared capabilities of various technological solutions to enable resolvability of data objects in dynamic datasets, and developed a dataset-centric approach to resolution of identifiers. This is particularly important in Semantic Linked Data environments where dynamic frequently changing data is delivered live via web services, so registration of individual data objects to obtain identifiers is impractical. We use identifier patterns and pattern hierarchies for identification of data objects, which allows relationships between identifiers to be expressed, and also provides means for resolving a single identifier into multiple forms (i.e. views or representations of an object). The latter can be implemented through (a) HTTP content negotiation, or (b) use of URI querystring parameters. The pattern and hierarchy approach has been implemented in the Linked Data API supporting the United Nations Spatial Data Infrastructure (UNSDI) initiative and later in the implementation of geoscientific data delivery for the Capricorn Distal Footprints project using International Geo Sample Numbers (IGSN). This enables flexible resolution of multi-view persistent identifiers and provides a scalable solution for large heterogeneous datasets.

  15. Identifying homelessness using health information exchange data. (United States)

    Zech, John; Husk, Gregg; Moore, Thomas; Kuperman, Gilad J; Shapiro, Jason S


    Homeless patients experience poor health outcomes and consume a disproportionate amount of health care resources compared with domiciled patients. There is increasing interest in the federal government in providing care coordination for homeless patients, which will require a systematic way of identifying these individuals. We analyzed address data from Healthix, a New York City-based health information exchange, to identify patterns that could indicate homelessness. Patients were categorized as likely to be homeless if they registered with the address of a hospital, homeless shelter, place of worship, or an address containing a keyword synonymous with "homelessness." We identified 78,460 out of 7,854,927 Healthix patients (1%) as likely to have been homeless over the study period of September 30, 2008 to July 19, 2013. We found that registration practices for these patients varied widely across sites. The use of health information exchange data enabled us to identify a large number of patients likely to be homeless and to observe the wide variation in registration practices for homeless patients within and across sites. Consideration of these results may suggest a way to improve the quality of record matching for homeless patients. Validation of these results is necessary to confirm the homeless status of identified individuals. Ultimately, creating a standardized and structured field to record a patient's housing status may be a preferable approach. © The Author 2015. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email:

  16. Identifying glass compositions in fly ash

    Directory of Open Access Journals (Sweden)

    Katherine eAughenbaugh


    Full Text Available In this study, four Class F fly ashes were studied with a scanning electron microscope; the glassy phases were identified and their compositions quantified using point compositional analysis with k-means clustering and multispectral image analysis. The results showed that while the bulk oxide contents of the fly ashes were different, the four fly ashes had somewhat similar glassy phase compositions. Aluminosilicate glasses (AS, calcium aluminosilicate glasses (CAS, a mixed glass, and, in one case, a high iron glass were identified in the fly ashes. Quartz and iron crystalline phases were identified in each fly ash as well. The compositions of the three main glasses identified, AS, CAS, and mixed glass, were relatively similar in each ash. The amounts of each glass were varied by fly ash, with the highest calcium fly ash containing the most of calcium-containing glass. Some of the glasses were identified as intermixed in individual particles, particularly the calcium-containing glasses. Finally, the smallest particles in the fly ashes, with the most surface area available to react in alkaline solution, such as when mixed with portland cement or in alkali-activated fly ash, were not different in composition than the large particles, with each of the glasses represented. The method used in the study may be applied to a fly ash of interest for use as a cementing material in order to understand its potential for reactivity.

  17. Identifying Adverse Drug Events by Relational Learning. (United States)

    Page, David; Costa, Vítor Santos; Natarajan, Sriraam; Barnard, Aubrey; Peissig, Peggy; Caldwell, Michael


    The pharmaceutical industry, consumer protection groups, users of medications and government oversight agencies are all strongly interested in identifying adverse reactions to drugs. While a clinical trial of a drug may use only a thousand patients, once a drug is released on the market it may be taken by millions of patients. As a result, in many cases adverse drug events (ADEs) are observed in the broader population that were not identified during clinical trials. Therefore, there is a need for continued, post-marketing surveillance of drugs to identify previously-unanticipated ADEs. This paper casts this problem as a reverse machine learning task , related to relational subgroup discovery and provides an initial evaluation of this approach based on experiments with an actual EMR/EHR and known adverse drug events.

  18. Photoacoustic tomography to identify inflammatory arthritis (United States)

    Rajian, Justin Rajesh; Girish, Gandikota; Wang, Xueding


    Identifying neovascularity (angiogenesis) as an early feature of inflammatory arthritis can help in early accurate diagnosis and treatment monitoring of this disease. Photoacoustic tomography (PAT) is a hybrid imaging modality which relies on intrinsic differences in the optical absorption among the tissues being imaged. Since blood has highly absorbing chromophores including both oxygenated and deoxygenated hemoglobin, PAT holds potential in identifying early angiogenesis associated with inflammatory joint diseases. PAT is used to identify changes in the development of inflammatory arthritis in a rat model. Imaging at two different wavelengths, 1064 nm and 532 nm, on rats revealed that there is a significant signal enhancement in the ankle joints of the arthritis affected rats when compared to the normal control group. Histology images obtained from both the normal and the arthritis affected rats correlated well with the PAT findings. Results support the fact that the emerging PAT could become a new tool for clinical management of inflammatory arthritis.

  19. Identifying motivational factors within a multinational company

    Directory of Open Access Journals (Sweden)

    Daniela Bradutanu


    Full Text Available The aim of the study is to identify the main motivational factors within a multinational company. The first objective is to identify work functions, formulated on Abraham Maslow’s pyramid, following the identification of the key characteristics that motivate an employee at the work place and last, but not least, the type of motivation that employees focus, intrinsic or extrinsic. The research method targeted a questionnaire based survey, including various company employees and an interview with the manager. The results confirmed that in Romania, employees put great emphasis on extrinsic motivation, a certain income and job security being primary. These results have implications for managers that in order to effectively motivate staff, first, must know their needs and expectations. To identify the main needs and motivational factors we had as a starting point Maslow's pyramid.

  20. Identifying Walking Trips Using GPS Data. (United States)

    Cho, Gi-Hyoug; Rodríguez, Daniel A; Evenson, Kelly R


    this study developed and tested algorithms to identify outdoor walking trips from portable global positioning system (GPS) units in free-living conditions. the study included a calibration and a validation phase. For the calibration phase, we determined the best algorithm from 35 person-days of data. Measures of agreement regarding the daily number and duration of diary-reported and GPS-identified trips were used. In the validation phase, the best algorithm was applied to an additional and separate 136 person-days of diary and GPS data. the preferred algorithm in the calibration phase resulted in 90% of trips identified from the GPS data being found in the diary, whereas 81% of trips reported in the diary being found in the GPS data. The preferred algorithm used 1) a maximum 3-min gap between points to define a trip, 2) at least 5 min or more of continuous GPS points, 3) a speed range between 2 and 8.0 km·h, 4) at least 30 m of displacement between the start and end points of a trip, and 5) merged walking trips when the time gap between trips was less than 3 min. With the validation data, substantial agreement between the GPS and the diary was achieved, with 86% of trips identified from the GPS data found in the diary and 77% of trips reported in the diary found in the GPS data. the algorithm identified free-living walking trips of more than 5 min in duration. The ability to identify outdoor walking trips from GPS data can be improved by reducing recording intervals used in the GPS units and monitoring participant compliance. Further research is desirable to determine whether concurrent wearing of an accelerometer may improve the ability to detect walking more accurately.

  1. Psychosocial counselling of identifiable sperm donors. (United States)

    Visser, M; Mochtar, M H; de Melker, A A; van der Veen, F; Repping, S; Gerrits, T


    What do identifiable sperm donors feel about psychosocial counselling? Identifiable sperm donors found it important that psychosocial counselling focused on emotional consequences and on rules and regulations and they expected to have access to psychosocial counselling at the time that donor-offspring actually sought contact. Most studies on sperm donors are on anonymous donors and focus on recruitment, financial compensation, anonymity and motivations. There is limited knowledge on the value that identifiable sperm donors place on psychosocial counselling and what their needs are in this respect. We performed a qualitative study from March until June 2014 with 25 identifiable sperm donors, who were or had been a donor at the Centre for Reproductive Medicine of the Academic Medical Centre in Amsterdam any time between 1989 and 2014. We held semi-structured in-depth interviews with identifiable sperm donors with an average age of 44 years. The interviews were fully transcribed and analysed using the constant comparative method of grounded theory. Twelve out of 15 donors (former donors ITALIC! n = 8, active donors ITALIC! n = 7) who had received a counselling session during their intake procedure found it important that they had been able to talk about issues such as the emotional consequences of donation, disclosure to their own children, family and friends, future contact with donor-offspring and rules and regulations. Of the 10 former donors who had received no counselling session, 8 had regretted the lack of intensive counselling. In the years following their donation, most donors simply wanted to know how many offspring had been born using their sperm and had no need for further counselling. Nevertheless, they frequently mentioned that they were concerned about the well-being of 'their' offspring. In addition, they would value the availability of psychosocial counselling in the event that donor-offspring actually sought contact. A limitation of our study is its

  2. Minimal covariant observables identifying all pure states

    Energy Technology Data Exchange (ETDEWEB)

    Carmeli, Claudio, E-mail: [D.I.M.E., Università di Genova, Via Cadorna 2, I-17100 Savona (Italy); I.N.F.N., Sezione di Genova, Via Dodecaneso 33, I-16146 Genova (Italy); Heinosaari, Teiko, E-mail: [Turku Centre for Quantum Physics, Department of Physics and Astronomy, University of Turku (Finland); Toigo, Alessandro, E-mail: [Dipartimento di Matematica, Politecnico di Milano, Piazza Leonardo da Vinci 32, I-20133 Milano (Italy); I.N.F.N., Sezione di Milano, Via Celoria 16, I-20133 Milano (Italy)


    It has been recently shown by Heinosaari, Mazzarella and Wolf (2013) [1] that an observable that identifies all pure states of a d-dimensional quantum system has minimally 4d−4 outcomes or slightly less (the exact number depending on d). However, no simple construction of this type of minimal observable is known. We investigate covariant observables that identify all pure states and have minimal number of outcomes. It is shown that the existence of this kind of observables depends on the dimension of the Hilbert space.

  3. Molecular Fingerprints to Identify Candida Species

    Directory of Open Access Journals (Sweden)

    Claudia Spampinato


    Full Text Available A wide range of molecular techniques have been developed for genotyping Candida species. Among them, multilocus sequence typing (MLST and microsatellite length polymorphisms (MLP analysis have recently emerged. MLST relies on DNA sequences of internal regions of various independent housekeeping genes, while MLP identifies microsatellite instability. Both methods generate unambiguous and highly reproducible data. Here, we review the results achieved by using these two techniques and also provide a brief overview of a new method based on high-resolution DNA melting (HRM. This method identifies sequence differences by subtle deviations in sample melting profiles in the presence of saturating fluorescent DNA binding dyes.

  4. Identifying gaps in international food safety regulation. (United States)

    McGrady, Benn; Ho, Christina S


    The rise in food importation in countries such as the United States, coupled with food safety incidents, has led to increased concern with the safety of imported food. This concern has prompted discussion of how international law and governance mechanisms might enhance food safety. This paper identifies the objectives underlying multilateral approaches to food safety such as raising food safety standards abroad, information sharing and ensuring market access. The paper then explores how these objectives are integrated into the international system and identifies how the current state of the law creates imbalances in the pursuit of these objectives.

  5. Identifying jet quantum numbers event by event

    International Nuclear Information System (INIS)

    Teper, M.J.


    A method is proposed to identify the parton that gives rise to any particular jet. The method improves with the number of particles in the jet, and should indicate which of the jets in a three jet event at PETRA is the gluon jet. (author)

  6. Structural identifiability of polynomial and rational systems

    NARCIS (Netherlands)

    J. Nemcová (Jana)


    htmlabstractSince analysis and simulation of biological phenomena require the availability of their fully specified models, one needs to be able to estimate unknown parameter values of the models. In this paper we deal with identifiability of parametrizations which is the property of one-to-one

  7. Identifying motifs in folktales using topic models

    NARCIS (Netherlands)

    Karsdorp, F.; Bosch, A.P.J. van den


    With the undertake of various folktale digitalization initiatives, the need for computational aids to explore these collections is increasing. In this paper we compare Labeled LDA (L-LDA) to a simple retrieval model on the task of identifying motifs in folktales. We show that both methods are well

  8. 10 Ways to Identify Hearing Loss (United States)

    ... of this page please turn JavaScript on. Feature: Hearing Loss 10 Ways to Identify Hearing Loss Past Issues / Spring 2015 Table of Contents If ... gov Internet: Read More "Hearing Loss" Articles Managing Hearing Loss / Symptoms, Devices, Prevention & Research / ...

  9. Identifying Mixtures of Mixtures Using Bayesian Estimation (United States)

    Malsiner-Walli, Gertraud; Frühwirth-Schnatter, Sylvia; Grün, Bettina


    ABSTRACT The use of a finite mixture of normal distributions in model-based clustering allows us to capture non-Gaussian data clusters. However, identifying the clusters from the normal components is challenging and in general either achieved by imposing constraints on the model or by using post-processing procedures. Within the Bayesian framework, we propose a different approach based on sparse finite mixtures to achieve identifiability. We specify a hierarchical prior, where the hyperparameters are carefully selected such that they are reflective of the cluster structure aimed at. In addition, this prior allows us to estimate the model using standard MCMC sampling methods. In combination with a post-processing approach which resolves the label switching issue and results in an identified model, our approach allows us to simultaneously (1) determine the number of clusters, (2) flexibly approximate the cluster distributions in a semiparametric way using finite mixtures of normals and (3) identify cluster-specific parameters and classify observations. The proposed approach is illustrated in two simulation studies and on benchmark datasets. Supplementary materials for this article are available online. PMID:28626349

  10. Congenital Heart Diseases associated with Identified Syndromes ...

    African Journals Online (AJOL)

    Recognised syndromes were seen in 69(68%) cases. Down syndrome with 54 children contributed 78.3% of those with known syndromes. Other identified syndromes and associations were Marfan's, Noonan's, Edwards, Prune Belly, Apert, Ellis-van creveld syndrome and congenital rubella syndrome. Congenital heart ...

  11. Transverse momentum distributions of identified particles produced ...

    Indian Academy of Sciences (India)

    We assume that the transverse momentum distributions of identified particles measured in final state are contributed by a few energy sources which can be regarded as partons or quarks in the interacting system. The particle is contributed by each source with gluons which have transverse momentum distributions in an ...

  12. Teaching science students to identify entrepreneurial opportunities

    NARCIS (Netherlands)

    Nab, J.|info:eu-repo/dai/nl/304827614


    This dissertation describes a research project on teaching science students to identify entrepreneurial opportunities, which is a core competence for entrepreneurs that should be emphasized in education. This research consists of four studies. The first case study aims at finding design strategies

  13. Identifying Protein-Calorie Malnutrition Workshop. (United States)

    Walker, Susan S.; Barker, Ellen M.

    Instructional materials are provided for a workshop to enable participants to assist in identifying patients at risk with protein-calorie malnutrition and in corrrecting this nutritional deficiency. Representative topics are nutrients; protein, mineral, and vitamin sources, functions, and deficiency symptoms; malnutrition; nutritional deficiency…

  14. Identifying Ethical Hypernorms for Accounting Educators (United States)

    Siegel, Philip H.; Mintz, Steven; Naser-Tavakolian, Mohsen; O'Shaughnessy, John


    Accounting educators have a unique role in academe because students learn about codes of ethics that will guide their actions as professionals. We identify hypernorms related to internal auditing educators that reflect unethical behaviors believed to be universally unacceptable by that community. We then compare the results to a prior survey of…

  15. Identifying Sexual Harassment: A Classroom Activity (United States)

    Madson, Laura; Shoda, Jennifer


    We created a classroom activity to illustrate the complexity involved in identifying sexual harassment. In the activity, students decided whether 6 fictional scenarios constituted sexual harassment. The activity stimulates animated discussion, and evaluation data indicate that it received positive feedback from students and refined students'…

  16. Problems Identifying Independent and Dependent Variables (United States)

    Leatham, Keith R.


    This paper discusses one step from the scientific method--that of identifying independent and dependent variables--from both scientific and mathematical perspectives. It begins by analyzing an episode from a middle school mathematics classroom that illustrates the need for students and teachers alike to develop a robust understanding of…

  17. Representing biodiversity: data and procedures for identifying ...

    Indian Academy of Sciences (India)


    alternative uses of biological resources, the methods for identifying priority areas have to ... conservation investment and make enlightened trade-offs. Negotiation can be ..... The energy and commitment of those involved in the Costa Rican. Figure 1. Three kinds of areas × features matrices showing (A) presence only data,.

  18. Identifying the Multiple Intelligences of Your Students (United States)

    McClellan, Joyce A.; Conti, Gary J.


    One way of addressing individual differences among adult learners is to identify the Multiple Intelligences of the learner. Multiple Intelligences refers to the concept developed by Howard Gardner that challenges the traditional view of intelligence and explains the presence of nine different Multiple Intelligences. The purpose of this study was…

  19. Understanding intercellular communication in the brain: Identified ...

    Indian Academy of Sciences (India)

    Understanding intercellular communication in the brain: Identified neuromuscular synapses of the fruitfly. Drosophila serve as a model. The transmission of information between nerve cells in the brain takes place at specialized sites of contact, the synapses. Spatial interactions between synapses and temporal modulation of ...

  20. Klebsiella pneumoniae antibiotic resistance identified by atomic ...

    Indian Academy of Sciences (India)

    In particular, we studied Klebsiella pneumoniae bacteria provided by the Lavagna Hospital ASL4Liguria (Italy), where there are cases linked with antibiotics resistance of the Klebsiella pneumoniae. By comparing AFMimages of bacteria strains treated with different antibiotics is possible to identify unambiguously the ...

  1. Avoiding medication mixups. Identifiable imprint codes. (United States)

    Vasudevan, P; Del Gianni, T; Robertson, W O


    This study was done to determine if current imprinting of solid medication forms permits health care professionals to identify the manufacturers involved so as to be able to activate the hierarchic identification system mandated by the Food and Drug Administration. We tested 15 representatives of 6 groups of health professionals for their ability to identify the manufacturer after having examined 30 solid-dosage forms drawn from a pseudo-random sample of stock hospital formulary products. The correct identification of the manufacturer was the sole criterion. Of the 2,700 opportunities, the manufacturer was able to be identified for only 43%. Nurses and medical students had a 35% success rate, pharmacists and poison center specialists a 55% success rate, and residents and attending physicians a 40% rate. None approached 95% accuracy. Currently employed imprints fail in their objective to permit health care professionals--or the general public--to rapidly identify prescription drugs. The manufacturers' logotypes need to be modified if this identification system is to be implemented. We propose a simple voluntary collaborative effort by the pharmaceutical industry to solve the problem. PMID:9000855

  2. Identifying Barriers to Study Abroad Program Participation (United States)

    McKinley, Karen E.


    University administrators, industry professionals, and government leaders encourage college students to participate in study abroad programs. Despite an increase in the number of students going abroad, the percentage of students participating in global programs remain low. This study identified barriers to study abroad program participation at a…

  3. Identifying Teaching Methods that Engage Entrepreneurship Students (United States)

    Balan, Peter; Metcalfe, Mike


    Purpose: Entrepreneurship education particularly requires student engagement because of the complexity of the entrepreneurship process. The purpose of this paper is to describe how an established measure of engagement can be used to identify relevant teaching methods that could be used to engage any group of entrepreneurship students.…

  4. Identifying systematic DFT errors in catalytic reactions

    DEFF Research Database (Denmark)

    Christensen, Rune; Hansen, Heine Anton; Vegge, Tejs


    Using CO2 reduction reactions as examples, we present a widely applicable method for identifying the main source of errors in density functional theory (DFT) calculations. The method has broad applications for error correction in DFT calculations in general, as it relies on the dependence...

  5. Identifying particular places through experimental walking

    Directory of Open Access Journals (Sweden)

    Henrik Schultz


    Full Text Available Experimental walking can be used to identify particular places, design strategies and spatial visions for urban landscapes. Walking designers can explore sites and, in particular, their temporal dynamics and atmospheric particularities – both essential elements in making particular places. This article illustrates the benefits of this method, using the changing German city of Freiburg as an example.

  6. Identifying Foods causing Allergies/ Intolerances among Diabetic ...

    African Journals Online (AJOL)

    Objective: This study was designed to identify the foods that caused allergies / intolerances and symptoms of reaction experienced by diabetic patients attending State Specialist Hospital, Akure. Materials and Methods: Ninety-eight diabetics aged 30-80 years (30 males and 68 females) were included in the study.

  7. Guidelines for identifying suspect/counterfeit material

    Energy Technology Data Exchange (ETDEWEB)



    These guidelines are intended to assist users of products in identifying: substandard, misrepresented, or fraudulently marked items. The guidelines provide information about such topics as: precautions, inspection and testing, dispositioning identified items, installed inspection and reporting suspect/counterfeit materials. These guidelines apply to users who are developing procurement documents, product acceptance/verification methods, company procedures, work instructions, etc. The intent of these SM guidelines in relation to the Quality Assurance Program Description (QAPD) and implementing company Management Control Procedures is not to substitute or replace existing requirements, as defined in either the QAPD or company implementing instructions (Management Control Procedures). Instead, the guidelines are intended to provide a consolidated source of information addressing the issue of Suspect/Counterfeit materials. These guidelines provide an extensive suspect component listing and suspect indications listing. Users can quickly check their suspect items against the list of manufacturers products (i.e., type, LD. number, and nameplate information) by consulting either of these listings.

  8. Persistent Identifiers for Dutch cultural heritage institutions (United States)

    Ras, Marcel; Kruithof, Gijsbert


    Over the past years, more and more collections belonging to archives, libraries, media, museums, and knowledge institutes are being digitised and made available online. These are exciting times for ALM institutions. They are realising that, in the information society, their collections are goldmines. Unfortunately most heritage institutions in the Netherlands do not yet meet the basic preconditions for long-term availability of their collections. The digital objects often have no long lasting fixed reference yet. URL's and web addresses change. Some digital objects that were referenced in Europeana and other portals can no longer be found. References in scientific articles have a very short life span, which is damaging for scholarly research. In 2015, the Dutch Digital Heritage Network (NDE) has started a two-year work program to co-ordinate existing initiatives in order to improve the (long-term) accessibility of the Dutch digital heritage for a wide range of users, anytime, anyplace. The Digital Heritage Network is a partnership established on the initiative of the Ministry of Education, Culture and Science. The members of the NDE are large, national institutions that strive to professionally preserve and manage digital data, e.g. the National Library, The Netherlands Institute for Sound and Vision, the Netherlands Cultural Heritage Agency, the Royal Netherlands Academy of Arts and Sciences, the National Archive of the Netherlands and the DEN Foundation, and a growing number of associations and individuals both within and outside the heritage sector. By means of three work programmes the goals of the Network should be accomplished and improve the visibility, the usability and the sustainability of digital heritage. Each programme contains of a set of projects. Within the sustainability program a project on creating a model for persistent identifiers is taking place. The main goals of the project are (1) raise awareness among cultural heritage institutions on the

  9. An Xpert screen to identify carbapenemases

    Directory of Open Access Journals (Sweden)

    Mubin Kazi


    Full Text Available To prevent the spread of carbapenemases-producing Enterobacteriaceae (CPE active surveillance, contact isolation and cohorting infected patients should be practiced. Rectal swabs for the Xpert MDRO-assay of 32 patients were included. 71.85% were positive for targets incorporated into the MDRO-assay; whereas 28% were phenotypically not CRE and Xpert negative (9.37% had different mechanism [bla OXA]. The assay identified 59.3%, 9.37% and 3.1% as bla NDM, bla NDM+VIM and bla VIM, respectively. The assay is a screening test that identifies CPE harbouring organism within an hour and can be installed at tertiary-care facilities to screen colonized patients.

  10. Identifying Critical States through the Relevance Index

    Directory of Open Access Journals (Sweden)

    Andrea Roli


    Full Text Available The identification of critical states is a major task in complex systems, and the availability of measures to detect such conditions is of utmost importance. In general, criticality refers to the existence of two qualitatively different behaviors that the same system can exhibit, depending on the values of some parameters. In this paper, we show that the relevance index may be effectively used to identify critical states in complex systems. The relevance index was originally developed to identify relevant sets of variables in dynamical systems, but in this paper, we show that it is also able to capture features of criticality. The index is applied to two prominent examples showing slightly different meanings of criticality, namely the Ising model and random Boolean networks. Results show that this index is maximized at critical states and is robust with respect to system size and sampling effort. It can therefore be used to detect criticality.

  11. Relationship between flanker identifiability and compatibility effect. (United States)

    Schwarz, W; Mecklinger, A


    What is the relation between the identifiability of masked flankers and their ability to induce compatibility effects in a letter classification task? Using a within-subjects design (n = 8), we first determined identification performance for two flankers (H or N) around an irrelevant target letter as a function of the time (stimulus onset asynchrony, or SOA) after which the flankers were masked. In a second condition, subjects classified the central letter of the same stimulus patterns irrespectively of the identity of the flankers. The compatibility effects increased with increasing identification performance as a function of SOA, and we found a significant compatibility effect even at an SOA at which the identifiability of the flankers did not differ significantly from zero. We discuss the statistical power of our design and an interpretation of our results in terms of a dissociation between perceptual processes and processes directly activating the motor system (direct parameter specification; cf. Neumann, 1990).

  12. Trustworthy persistent identifier systems of the future (United States)

    Golodoniuc, Pavel; Klump, Jens; Car, Nicholas


    Over the last two decades, persistent identifier (PID) systems have seen some significant changes in their governance policies, system capabilities, and technology. The development of most systems was driven by two main application areas, namely archives and libraries. Guidelines and criteria for trustworthy PID systems have been clearly devised (Bütikofer, 2009) and many PID system implementations for the identification of static digital objects have been built (e.g., PURL). However systems delivering persistent identifiers for dynamic datasets are not yet mature. There has been a rapid proliferation of different PID systems caused by the specific technical or organisational requirements of various communities that could not be met by existing systems such as DOI, ISBN, and EAN. Many of these different systems were limited by their inability to provide native means of persistent identifier resolution. This has prompted a decoupling of PID-associated data from the resolution service and this is where the Handle system has played a significant role. The Handle allowed to build a distributed system of independently managed resolver services. A trustworthy PID system must be designed to outlive the objects it provides persistent identifiers for, which may cease to exist or otherwise be deprecated, and the technology used to implement it, which will certainly need to change with time. We propose that such a system should rest on four pillars of agreements - (i) definitions, (ii) policies, (iii) services, and (iv) data services, to ensure longevity. While we believe all four pillars are equally important, we intentionally leave regulating aspects of issuing of identifiers and their registration out of the scope of this paper and focus on the agreements that have to be established between PID resolver services and the data sources indicated by the persistent identifiers. We propose an approach to development of PID systems that combines the use of (a) the Handle system

  13. Identifying mechanistic similarities in drug responses

    KAUST Repository

    Zhao, C.


    Motivation: In early drug development, it would be beneficial to be able to identify those dynamic patterns of gene response that indicate that drugs targeting a particular gene will be likely or not to elicit the desired response. One approach would be to quantitate the degree of similarity between the responses that cells show when exposed to drugs, so that consistencies in the regulation of cellular response processes that produce success or failure can be more readily identified.Results: We track drug response using fluorescent proteins as transcription activity reporters. Our basic assumption is that drugs inducing very similar alteration in transcriptional regulation will produce similar temporal trajectories on many of the reporter proteins and hence be identified as having similarities in their mechanisms of action (MOA). The main body of this work is devoted to characterizing similarity in temporal trajectories/signals. To do so, we must first identify the key points that determine mechanistic similarity between two drug responses. Directly comparing points on the two signals is unrealistic, as it cannot handle delays and speed variations on the time axis. Hence, to capture the similarities between reporter responses, we develop an alignment algorithm that is robust to noise, time delays and is able to find all the contiguous parts of signals centered about a core alignment (reflecting a core mechanism in drug response). Applying the proposed algorithm to a range of real drug experiments shows that the result agrees well with the prior drug MOA knowledge. © The Author 2012. Published by Oxford University Press. All rights reserved.

  14. Identifiability Scaling Laws in Bilinear Inverse Problems


    Choudhary, Sunav; Mitra, Urbashi


    A number of ill-posed inverse problems in signal processing, like blind deconvolution, matrix factorization, dictionary learning and blind source separation share the common characteristic of being bilinear inverse problems (BIPs), i.e. the observation model is a function of two variables and conditioned on one variable being known, the observation is a linear function of the other variable. A key issue that arises for such inverse problems is that of identifiability, i.e. whether the observa...

  15. Discrimination of SM-Identified Individuals


    Wright, Susan


    The misconception that sadomasochism (SM) is violence or abusive behavior has resulted in significant persecution against SM-identified individuals in the form of discrimination, harassment and physical attacks. Historically, women who practiced SM were targeted within the feminist movement due to official opposition against sadomasochistic practices led by the National Organization for Women (NOW). Current statistics of incidents of discrimination, harassment and physical attacks against SM-...

  16. Which functional unit to identify sustainable foods? (United States)

    Masset, Gabriel; Vieux, Florent; Darmon, Nicole


    In life-cycle assessment, the functional unit defines the unit for calculation of environmental indicators. The objective of the present study was to assess the influence of two functional units, 100 g and 100 kcal (420 kJ), on the associations between three dimensions for identifying sustainable foods, namely environmental impact (via greenhouse gas emissions (GHGE)), nutritional quality (using two distinct nutrient profiling systems) and price. GHGE and price data were collected for individual foods, and were each expressed per 100 g and per 100 kcal. Two nutrient profiling models, SAIN,LIM and UK Ofcom, were used to assess foods' nutritional quality. Spearman correlations were used to assess associations between variables. Sustainable foods were identified as those having more favourable values for all three dimensions. The French Individual and National Dietary Survey (INCA2), 2006-2007. Three hundred and seventy-three foods highly consumed in INCA2, covering 65 % of total energy intake of adult participants. When GHGE and price were expressed per 100 g, low-GHGE foods had a lower price and higher SAIN,LIM and Ofcom scores (r=0·59, -0·34 and -0·43, respectively), suggesting a compatibility between the three dimensions; 101 and 100 sustainable foods were identified with SAIN,LIM and Ofcom, respectively. When GHGE and price were expressed per 100 kcal, low-GHGE foods had a lower price but also lower SAIN,LIM and Ofcom scores (r=0·67, 0·51 and 0·47, respectively), suggesting that more environment-friendly foods were less expensive but also less healthy; thirty-four sustainable foods were identified with both SAIN,LIM and Ofcom. The choice of functional unit strongly influenced the compatibility between the sustainability dimensions and the identification of sustainable foods.

  17. The Complexity of Identifying Large Equivalence Classes

    DEFF Research Database (Denmark)

    Skyum, Sven; Frandsen, Gudmund Skovbjerg; Miltersen, Peter Bro


    We prove that at least 3k−4/k(2k−3)(n/2) – O(k)equivalence tests and no more than 2/k (n/2) + O(n) equivalence tests are needed in the worst case to identify the equivalence classes with at least k members in set of n elements. The upper bound is an improvement by a factor 2 compared to known res...

  18. Transverse momentum distributions of identified particles produced ...

    Indian Academy of Sciences (India)

    Comparisons with experimental data. The pT spectra, in different presentation forms as used in [11,28–31], for identified parti- cles emitted in pp collisions at different centre-of-mass energies are shown in figures 1–4, where y, E, p, σ, and B denote the rapidity, energy, momentum, cross-section, and di- lepton branching ratio ...

  19. Identifying the Universal part of TMDs

    CERN Document Server

    Van der Veken, F.F.


    We attempt to identify a path layout in the definition of transverse-momentum-dependent T-odd parton distribution functions (TMD)s which combines features of both, initial- and final-state interactions, so that it remains universal despite the fact that the Wilson lines entering such TMDs change their orientation. The generic structure of the quark correlator for this path layout is calculated.

  20. Have No PHEAR: Networks Without Identifiers (United States)


    Ethernet and TCP/IP were not designed to ensure the security and privacy of users. To protect users’ pri- vacy, anonymity networks such as Tor have been...protocols that power the Internet were not developed with the security and privacy of users in mind, there are many opportunities for on-path network...IEEE 802 network (such as Eth- ernet or Wireless Ethernet networks, for example). This address is a globally unique identifier for the device’s network

  1. Identifying Topics in Microblogs Using Wikipedia.

    Directory of Open Access Journals (Sweden)

    Ahmet Yıldırım

    Full Text Available Twitter is an extremely high volume platform for user generated contributions regarding any topic. The wealth of content created at real-time in massive quantities calls for automated approaches to identify the topics of the contributions. Such topics can be utilized in numerous ways, such as public opinion mining, marketing, entertainment, and disaster management. Towards this end, approaches to relate single or partial posts to knowledge base items have been proposed. However, in microblogging systems like Twitter, topics emerge from the culmination of a large number of contributions. Therefore, identifying topics based on collections of posts, where individual posts contribute to some aspect of the greater topic is necessary. Models, such as Latent Dirichlet Allocation (LDA, propose algorithms for relating collections of posts to sets of keywords that represent underlying topics. In these approaches, figuring out what the specific topic(s the keyword sets represent remains as a separate task. Another issue in topic detection is the scope, which is often limited to specific domain, such as health. This work proposes an approach for identifying domain-independent specific topics related to sets of posts. In this approach, individual posts are processed and then aggregated to identify key tokens, which are then mapped to specific topics. Wikipedia article titles are selected to represent topics, since they are up to date, user-generated, sophisticated articles that span topics of human interest. This paper describes the proposed approach, a prototype implementation, and a case study based on data gathered during the heavily contributed periods corresponding to the four US election debates in 2012. The manually evaluated results (0.96 precision and other observations from the study are discussed in detail.

  2. Identifying Topics in Microblogs Using Wikipedia. (United States)

    Yıldırım, Ahmet; Üsküdarlı, Suzan; Özgür, Arzucan


    Twitter is an extremely high volume platform for user generated contributions regarding any topic. The wealth of content created at real-time in massive quantities calls for automated approaches to identify the topics of the contributions. Such topics can be utilized in numerous ways, such as public opinion mining, marketing, entertainment, and disaster management. Towards this end, approaches to relate single or partial posts to knowledge base items have been proposed. However, in microblogging systems like Twitter, topics emerge from the culmination of a large number of contributions. Therefore, identifying topics based on collections of posts, where individual posts contribute to some aspect of the greater topic is necessary. Models, such as Latent Dirichlet Allocation (LDA), propose algorithms for relating collections of posts to sets of keywords that represent underlying topics. In these approaches, figuring out what the specific topic(s) the keyword sets represent remains as a separate task. Another issue in topic detection is the scope, which is often limited to specific domain, such as health. This work proposes an approach for identifying domain-independent specific topics related to sets of posts. In this approach, individual posts are processed and then aggregated to identify key tokens, which are then mapped to specific topics. Wikipedia article titles are selected to represent topics, since they are up to date, user-generated, sophisticated articles that span topics of human interest. This paper describes the proposed approach, a prototype implementation, and a case study based on data gathered during the heavily contributed periods corresponding to the four US election debates in 2012. The manually evaluated results (0.96 precision) and other observations from the study are discussed in detail.

  3. Identified particles in quark and gluon jets

    CERN Document Server

    Abreu, P; Adye, T; Ajinenko, I; Alekseev, G D; Alemany, R; Allport, P P; Almehed, S; Amaldi, Ugo; Amato, S; Andreazza, A; Andrieux, M L; Antilogus, P; Apel, W D; Åsman, B; Augustin, J E; Augustinus, A; Baillon, Paul; Bambade, P; Barão, F; Barbi, M S; Barbiellini, Guido; Bardin, Dimitri Yuri; Barker, G; Baroncelli, A; Bärring, O; Barrio, J A; Bartl, Walter; Bates, M J; Battaglia, Marco; Baubillier, M; Baudot, J; Becks, K H; Begalli, M; Beillière, P; Belokopytov, Yu A; Benvenuti, Alberto C; Berggren, M; Bertini, D; Bertrand, D; Besançon, M; Bianchi, F; Bigi, M; Bilenky, S M; Billoir, P; Bizouard, M A; Bloch, D; Blume, M; Bolognese, T; Bonesini, M; Bonivento, W; Booth, P S L; Bosio, C; Botner, O; Boudinov, E; Bouquet, B; Bourdarios, C; Bowcock, T J V; Bozzo, M; Branchini, P; Brand, K D; Brenke, T; Brenner, R A; Bricman, C; Brown, R C A; Brückman, P; Brunet, J M; Bugge, L; Buran, T; Burgsmüller, T; Buschmann, P; Cabrera, S; Caccia, M; Calvi, M; Camacho-Rozas, A J; Camporesi, T; Canale, V; Canepa, M; Cankocak, K; Cao, F; Carena, F; Carroll, L; Caso, Carlo; Castillo-Gimenez, M V; Cattai, A; Cavallo, F R; Chabaud, V; Charpentier, P; Chaussard, L; Checchia, P; Chelkov, G A; Chen, M; Chierici, R; Chliapnikov, P V; Chochula, P; Chorowicz, V; Chudoba, J; Cindro, V; Collins, P; Contri, R; Cortina, E; Cosme, G; Cossutti, F; Cowell, J H; Crawley, H B; Crennell, D J; Crosetti, G; Cuevas-Maestro, J; Czellar, S; Dahl-Jensen, Erik; Dahm, J; D'Almagne, B; Dam, M; Damgaard, G; Dauncey, P D; Davenport, Martyn; Da Silva, W; Defoix, C; Deghorain, A; Della Ricca, G; Delpierre, P A; Demaria, N; De Angelis, A; de Boer, Wim; De Brabandere, S; De Clercq, C; La Vaissière, C de; De Lotto, B; De Min, A; De Paula, L S; De Saint-Jean, C; Dijkstra, H; Di Ciaccio, Lucia; Di Diodato, A; Djama, F; Djannati, A; Dolbeau, J; Doroba, K; Dracos, M; Drees, J; Drees, K A; Dris, M; Durand, J D; Edsall, D M; Ehret, R; Eigen, G; Ekelöf, T J C; Ekspong, Gösta; Elsing, M; Engel, J P; Erzen, B; Espirito-Santo, M C; Falk, E; Fassouliotis, D; Feindt, Michael; Ferrer, A; Fichet, S; Filippas-Tassos, A; Firestone, A; Fischer, P A; Föth, H; Fokitis, E; Fontanelli, F; Formenti, F; Franek, B J; Frenkiel, P; Fries, D E C; Frodesen, A G; Frühwirth, R; Fulda-Quenzer, F; Fuster, J A; Galloni, A; Gamba, D; Gandelman, M; García, C; García, J; Gaspar, C; Gasparini, U; Gavillet, P; Gazis, E N; Gelé, D; Gerber, J P; Gerdyukov, L N; Gokieli, R; Golob, B; Gopal, Gian P; Gorn, L; Górski, M; Guz, Yu; Gracco, Valerio; Graziani, E; Green, C; Grefrath, A; Gris, P; Grosdidier, G; Grzelak, K; Gumenyuk, S A; Gunnarsson, P; Günther, M; Guy, J; Hahn, F; Hahn, S; Hajduk, Z; Hallgren, A; Hamacher, K; Harris, F J; Hedberg, V; Henriques, R P; Hernández, J J; Herquet, P; Herr, H; Hessing, T L; Heuser, J M; Higón, E; Hilke, Hans Jürgen; Hill, T S; Holmgren, S O; Holt, P J; Holthuizen, D J; Hoorelbeke, S; Houlden, M A; Hrubec, Josef; Huet, K; Hultqvist, K; Jackson, J N; Jacobsson, R; Jalocha, P; Janik, R; Jarlskog, C; Jarlskog, G; Jarry, P; Jean-Marie, B; Johansson, E K; Jönsson, L B; Jönsson, P E; Joram, Christian; Juillot, P; Kaiser, M; Kapusta, F; Karafasoulis, K; Karlsson, M; Karvelas, E; Katargin, A; Katsanevas, S; Katsoufis, E C; Keränen, R; Khokhlov, Yu A; Khomenko, B A; Khovanskii, N N; King, B J; Kjaer, N J; Klapp, O; Klein, H; Klovning, A; Kluit, P M; Köne, B; Kokkinias, P; Koratzinos, M; Korcyl, K; Kostyukhin, V; Kourkoumelis, C; Kuznetsov, O; Krammer, Manfred; Kreuter, C; Kronkvist, I J; Krumshtein, Z; Krupinski, W; Kubinec, P; Kucewicz, W; Kurvinen, K L; Lacasta, C; Laktineh, I; Lamsa, J; Lanceri, L; Lane, D W; Langefeld, P; Lapin, V; Laugier, J P; Lauhakangas, R; Leder, Gerhard; Ledroit, F; Lefébure, V; Legan, C K; Leitner, R; Lemonne, J; Lenzen, Georg; Lepeltier, V; Lesiak, T; Libby, J; Liko, D; Lindner, R; Lipniacka, A; Lippi, I; Lörstad, B; Loken, J G; López, J M; Loukas, D; Lutz, P; Lyons, L; MacNaughton, J N; Maehlum, G; Mahon, J R; Malmgren, T G M; Malychev, V; Mandl, F; Marco, J; Marco, R P; Maréchal, B; Margoni, M; Marin, J C; Mariotti, C; Markou, A; Martínez-Rivero, C; Martínez-Vidal, F; Martí i García, S; Masik, J; Matorras, F; Matteuzzi, C; Matthiae, Giorgio; Mazzucato, M; McCubbin, M L; McKay, R; McNulty, R; Medbo, J; Merk, M; Meroni, C; Meyer, S; Meyer, W T; Michelotto, M; Migliore, E; Mirabito, L; Mitaroff, Winfried A; Mjörnmark, U; Moa, T; Møller, R; Mönig, K; Monge, M R; Morettini, P; Müller, H; Münich, K; Mulders, M; Mundim, L M; Murray, W J; Muryn, B; Myatt, Gerald; Naraghi, F; Navarria, Francesco Luigi; Navas, S; Nawrocki, K; Negri, P; Neumann, W; Neumeister, N; Nicolaidou, R; Nielsen, B S; Nieuwenhuizen, M; Nikolaenko, V; Niss, P; Nomerotski, A; Normand, Ainsley; Novák, M; Oberschulte-Beckmann, W; Obraztsov, V F; Olshevskii, A G; Onofre, A; Orava, Risto; Österberg, K; Ouraou, A; Paganini, P; Paganoni, M; Pagès, P; Pain, R; Palka, H; Papadopoulou, T D; Papageorgiou, K; Pape, L; Parkes, C; Parodi, F; Passeri, A; Pegoraro, M; Peralta, L; Pernicka, Manfred; Perrotta, A; Petridou, C; Petrolini, A; Petrovykh, M; Phillips, H T; Piana, G; Pierre, F; Pimenta, M; Podobnik, T; Podobrin, O; Pol, M E; Polok, G; Poropat, P; Pozdnyakov, V; Privitera, P; Pukhaeva, N; Pullia, Antonio; Radojicic, D; Ragazzi, S; Rahmani, H; Rames, J; Ratoff, P N; Read, A L; Reale, M; Rebecchi, P; Redaelli, N G; Regler, Meinhard; Reid, D; Reinhardt, R; Renton, P B; Resvanis, L K; Richard, F; Richardson, J; Rídky, J; Rinaudo, G; Ripp, I; Romero, A; Roncagliolo, I; Ronchese, P; Roos, L; Rosenberg, E I; Roudeau, Patrick; Rovelli, T; Rückstuhl, W; Ruhlmann-Kleider, V; Ruiz, A; Rybicki, K; Rybin, A; Saarikko, H; Sacquin, Yu; Sadovskii, A; Sahr, O; Sajot, G; Salt, J; Sánchez, J; Sannino, M; Schimmelpfennig, M; Schneider, H; Schwickerath, U; Schyns, M A E; Sciolla, G; Scuri, F; Seager, P; Sedykh, Yu; Segar, A M; Seitz, A; Sekulin, R L; Serbelloni, L; Shellard, R C; Siegrist, P; Silvestre, R; Simonetti, S; Simonetto, F; Sissakian, A N; Sitár, B; Skaali, T B; Smadja, G; Smirnov, N; Smirnova, O G; Smith, G R; Sosnowski, R; Souza-Santos, D; Spassoff, Tz; Spiriti, E; Sponholz, P; Squarcia, S; Stampfer, D; Stanescu, C; Stanic, S; Stapnes, Steinar; Stavitski, I; Stevenson, K; Stocchi, A; Strauss, J; Strub, R; Stugu, B; Szczekowski, M; Szeptycka, M; Tabarelli de Fatis, T; Tavernet, J P; Chikilev, O G; Thomas, J; Tilquin, A; Timmermans, J; Tkatchev, L G; Todorov, T; Todorova, S; Toet, D Z; Tomaradze, A G; Tomé, B; Tonazzo, A; Tortora, L; Tranströmer, G; Treille, D; Tristram, G; Trombini, A; Troncon, C; Tsirou, A L; Turluer, M L; Tyapkin, I A; Tyndel, M; Tzamarias, S; Überschär, B; Ullaland, O; Uvarov, V; Valenti, G; Vallazza, E; Van der Velde, C; van Apeldoorn, G W; van Dam, P; Van Doninck, W K; Van Eldik, J; Van Lysebetten, A; Vassilopoulos, N; Vegni, G; Ventura, L; Venus, W A; Verbeure, F; Verlato, M; Vertogradov, L S; Vilanova, D; Vincent, P; Vitale, L; Vlasov, E; Vodopyanov, A S; Vrba, V; Wahlen, H; Walck, C; Weierstall, M; Weilhammer, Peter; Weiser, C; Wetherell, Alan M; Wicke, D; Wickens, J H; Wielers, M; Wilkinson, G R; Williams, W S C; Winter, M; Witek, M; Wlodek, T; Woschnagg, K; Yip, K; Yushchenko, O P; Zach, F; Zaitsev, A; Zalewska-Bak, A; Zalewski, Piotr; Zavrtanik, D; Zevgolatakos, E; Zimin, N I; Zito, M; Zontar, D; Zucchelli, G C; Zumerle, G


    A sample of about 1.4 million hadronic \\z decays, selected among the data recorded by the DELPHI detector at LEP during 1994, was used to measure for the first time the momentum spectra of \\kp, \\ko, \\p, \\l and their antiparticles in gluon and quark jets. As observed for inclusive charged particles, the production spectra of identified particles were found to be softer in gluon jets than in quark jets, with a higher total multiplicity.

  4. Identifying Tracks Duplicates via Neural Network

    CERN Document Server

    Sunjerga, Antonio; CERN. Geneva. EP Department


    The goal of the project is to study feasibility of state of the art machine learning techniques in track reconstruction. Machine learning techniques provide promising ways to speed up the pattern recognition of tracks by adding more intelligence in the algorithms. Implementation of neural network to process of track duplicates identifying will be discussed. Different approaches are shown and results are compared to method that is currently in use.

  5. Decoding of Baby Calls: Can Adult Humans Identify the Eliciting Situation from Emotional Vocalizations of Preverbal Infants?

    Directory of Open Access Journals (Sweden)

    Jitka Lindová

    Full Text Available Preverbal infants often vocalize in emotionally loaded situations, yet the communicative potential of these vocalizations is not well understood. The aim of our study was to assess how accurately adult listeners extract information about the eliciting situation from infant preverbal vocalizations. Vocalizations of 19 infants aged 5-10 months were recorded in 3 negative (Pain, Isolation, Demand for Food and 3 positive (Play, Reunion, After Feeding situations. The recordings were later rated by 333 adult listeners on the scales of emotional valence and intensity. Subsequently, the listeners assigned the eliciting situations in a forced choice task. Listeners were almost perfectly able to discriminate whether a recording came from a negative or a positive situation. Their discrimination may have been based on perceived valence as they consistently assigned higher valence when listening to positive, and lower valence when listening to negative, recordings. Ability to identify the particular situation within the negative or positive realm was substantially weaker, with only three of the six situations being discriminated above chance. The best discriminated situation, Play, was associated with high perceived intensity. The weak qualitative discrimination of negative situations seemed to be based on graded perception of negative recordings, from the most intense and unpleasant (assigned to Pain to the least intense and least unpleasant (assigned to Demand for Food. Parenthood and younger age, but not gender of listeners, had weak positive effects on the accuracy of judgments. Our results indicate that adults almost flawlessly distinguish positive and negative infant sounds, but are rather inaccurate regarding identification of the specific needs of the infant and may normally employ other sensory channels to gain this information.

  6. Identifying web usage behavior of bank customers (United States)

    Araya, Sandro; Silva, Mariano; Weber, Richard


    The bank Banco Credito e Inversiones (BCI) started its virtual bank in 1996 and its registered customers perform currently more than 10,000 Internet transactions daily, which typically cause les than 10% of traditional transaction costs. Since most of the customers are still not registered for online banking, one of the goals of the virtual bank is to increase then umber of registered customers. Objective of the presented work was to identify customers who are likely to perform online banking but still do not use this medium for their transactions. This objective has been reached by determining profiles of registered customers who perform many transactions online. Based on these profiles the bank's Data Warehouse is explored for twins of these heavy users that are still not registered for online banking. We applied clustering in order to group the registered customers into five classes. One of these classes contained almost 30% of all registered customers and could clearly be identified as class of heavy users. Next a neural network assigned online customers to the previously found five classes. Applying the network trained on online customers to all the bank customers identified twins of heavy users that, however had not performed online transactions so far. A mailing to these candidates informing about the advantages of online banking doubled the number of registrations compared to previous campaigns.

  7. Identifying Broadband Rotational Spectra with Neural Networks (United States)

    Zaleski, Daniel P.; Prozument, Kirill


    A typical broadband rotational spectrum may contain several thousand observable transitions, spanning many species. Identifying the individual spectra, particularly when the dynamic range reaches 1,000:1 or even 10,000:1, can be challenging. One approach is to apply automated fitting routines. In this approach, combinations of 3 transitions can be created to form a "triple", which allows fitting of the A, B, and C rotational constants in a Watson-type Hamiltonian. On a standard desktop computer, with a target molecule of interest, a typical AUTOFIT routine takes 2-12 hours depending on the spectral density. A new approach is to utilize machine learning to train a computer to recognize the patterns (frequency spacing and relative intensities) inherit in rotational spectra and to identify the individual spectra in a raw broadband rotational spectrum. Here, recurrent neural networks have been trained to identify different types of rotational spectra and classify them accordingly. Furthermore, early results in applying convolutional neural networks for spectral object recognition in broadband rotational spectra appear promising. Perez et al. "Broadband Fourier transform rotational spectroscopy for structure determination: The water heptamer." Chem. Phys. Lett., 2013, 571, 1-15. Seifert et al. "AUTOFIT, an Automated Fitting Tool for Broadband Rotational Spectra, and Applications to 1-Hexanal." J. Mol. Spectrosc., 2015, 312, 13-21. Bishop. "Neural networks for pattern recognition." Oxford university press, 1995.

  8. Metabolites of cannabidiol identified in human urine. (United States)

    Harvey, D J; Mechoulam, R


    1. Urine from a dystonic patient treated with cannabidiol (CBD) was examined by g.l.c.-mass spectrometry for CBD metabolites. Metabolites were identified as their trimethylsilyl (TMS), [2H9]TMS, and methyl ester/TMS derivatives and as the TMS derivatives of the product of lithium aluminium deuteride reduction. 2. Thirty-three metabolites were identified in addition to unmetabolized CBD, and a further four metabolites were partially characterized. 3. The major metabolic route was hydroxylation and oxidation at C-7 followed by further hydroxylation in the pentyl and propenyl groups to give 1"-, 2"-, 3"-, 4"- and 10-hydroxy derivatives of CBD-7-oic acid. Other metabolites, mainly acids, were formed by beta-oxidation and related biotransformations from the pentyl side-chain and these were also hydroxylated at C-6 or C-7. The major oxidized metabolite was CBD-7-oic acid containing a hydroxyethyl side-chain. 4. Two 8,9-dihydroxy compounds, presumably derived from the corresponding epoxide were identified. 5. Also present were several cyclized cannabinoids including delta-6- and delta-1-tetrahydrocannabinol and cannabinol. 6. This is the first metabolic study of CBD in humans; most observed metabolic routes were typical of those found for CBD and related cannabinoids in other species.

  9. Bisexual Phenomena Among Gay-Identified Men. (United States)

    Semon, Theodore L; Hsu, Kevin J; Rosenthal, A M; Bailey, J Michael


    A high proportion of self-identified gay men exhibit aspects of bisexuality during their lives. Some identify as bisexual before later identifying as gay; this has been called transitional bisexuality. Although many gay men report no attraction to women-or even sexual disgust toward them-others report some slight attraction to women. The latter have been studied as mostly homosexual men. We studied men with and without a history of transitional bisexuality, as well as mostly homosexual (i.e., those with Kinsey scores of 5) and completely homosexual (i.e., those with Kinsey scores of 6) men with respect to their sexual history with women, their current self-reported sexual arousal and disgust toward women and men, and their patterns of genital sexual arousal to female and male stimuli. Gay men with a history of transitional bisexuality generally lacked current sexual attraction and sexual arousal to women, compared with other gay men. Thus, transitional bisexuality among future gay men is mostly a matter of transitional bisexual identification. In contrast, mostly homosexual men showed statistically significant increases in genital arousal to female stimuli, compared with completely homosexual men.

  10. Persistent Identifiers, Discoverability and Open Science (Communication) (United States)

    Murphy, Fiona; Lehnert, Kerstin; Hanson, Brooks


    Early in 2016, the American Geophysical Union announced it was incorporating ORCIDs into its submission workflows. This was accompanied by a strong statement supporting the use of other persistent identifiers - such as IGSNs, and the CrossRef open registry 'funding data'. This was partly in response to funders' desire to track and manage their outputs. However the more compelling argument, and the reason why the AGU has also signed up to the Center for Open Science's Transparency and Openness Promotion (TOP) Guidelines (, is that ultimately science and scientists will be the richer for these initiatives due to increased opportunities for interoperability, reproduceability and accreditation. The AGU has appealed to the wider community to engage with these initiatives, recognising that - unlike the introduction of Digital Object Identifiers (DOIs) for articles by CrossRef - full, enriched use of persistent identifiers throughout the scientific process requires buy-in from a range of scholarly communications stakeholders. At the same time, across the general research landscape, initiatives such as Project CRediT (contributor roles taxonomy), Publons (reviewer acknowledgements) and the forthcoming CrossRef DOI Event Tracker are contributing to our understanding and accreditation of contributions and impact. More specifically for earth science and scientists, the cross-functional Coalition for Publishing Data in the Earth and Space Sciences (COPDESS) was formed in October 2014 and is working to 'provide an organizational framework for Earth and space science publishers and data facilities to jointly implement and promote common policies and procedures for the publication and citation of data across Earth Science journals'. Clearly, the judicious integration of standards, registries and persistent identifiers such as ORCIDs and International Geo Sample Numbers (IGSNs) to the research and research output processes is key to the success of this venture

  11. Body linear traits for identifying prolific goats

    Directory of Open Access Journals (Sweden)

    Avijit Haldar


    Full Text Available Aim: The present study was conducted on prolific goat breed to identify body linear type traits that might be associated with prolificacy trait in goats. Materials and Methods: Two-stage stratified random sample survey based data were collected from 1427 non-pregnant goats with the history of single, twin and triplet litter sizes (LZ between January 2008 to February 2011 for 3 years in 68 villages located in East and North East India. Data on sixteen body linear traits were analyzed using logistic regression model to do the step-wise selection for identifying the body linear traits that could determine LZ. An average value for each identified body linear trait was determined for classifying the goats into three categories: Goats having the history of single LZ, goats having the history of twin LZ and goats having the history of triplet LZ. Results: The LZ proportions for single, twin and triplet, were 29.50, 59.14 and 11.36%, respectively, with the prolificacy rate of 181.85% in Indian Black Bengal goats. A total of eight body linear traits that could determine LZ in prolific goats were identified. Heart girth (HG measurement (>60.90 cm, paunch girth (PG (>70.22 cm, wither height (WH (>49.75 cm, neck length (>21.45 cm, ear length (>12.80 cm and distance between trochanter major (DTM bones (>12.28 cm, pelvic triangle area (PTA (>572.25 cm2 and clearance at udder (CU (>23.16 cm showed an increase likelihood of multiple LZ when compared to single LZ. Further, HG measurement (>62.29 cm, WH (>50.54 cm, PG (>71.85 cm and ear length (>13.00 cm, neck length (>22.01 cm, PTA (>589.64 cm2, CU (>23.20 cm and DTM bones (>12.47 cm were associated with increased likelihood of triplet LZ, when compared with that of twin LZ. Conclusion: HG measurement was the best discriminating factor, while PG, neck length, DTM bones, CU, PTA, WH and ear length measurements were other important factors that could be used for identifying prolific goats to achieve economic

  12. Identifying novel drug indications through automated reasoning.

    Directory of Open Access Journals (Sweden)

    Luis Tari

    Full Text Available With the large amount of pharmacological and biological knowledge available in literature, finding novel drug indications for existing drugs using in silico approaches has become increasingly feasible. Typical literature-based approaches generate new hypotheses in the form of protein-protein interactions networks by means of linking concepts based on their cooccurrences within abstracts. However, this kind of approaches tends to generate too many hypotheses, and identifying new drug indications from large networks can be a time-consuming process.In this work, we developed a method that acquires the necessary facts from literature and knowledge bases, and identifies new drug indications through automated reasoning. This is achieved by encoding the molecular effects caused by drug-target interactions and links to various diseases and drug mechanism as domain knowledge in AnsProlog, a declarative language that is useful for automated reasoning, including reasoning with incomplete information. Unlike other literature-based approaches, our approach is more fine-grained, especially in identifying indirect relationships for drug indications.To evaluate the capability of our approach in inferring novel drug indications, we applied our method to 943 drugs from DrugBank and asked if any of these drugs have potential anti-cancer activities based on information on their targets and molecular interaction types alone. A total of 507 drugs were found to have the potential to be used for cancer treatments. Among the potential anti-cancer drugs, 67 out of 81 drugs (a recall of 82.7% are indeed known cancer drugs. In addition, 144 out of 289 drugs (a recall of 49.8% are non-cancer drugs that are currently tested in clinical trials for cancer treatments. These results suggest that our method is able to infer drug indications (original or alternative based on their molecular targets and interactions alone and has the potential to discover novel drug indications for

  13. Identifying single copy orthologs in Metazoa.

    Directory of Open Access Journals (Sweden)

    Christopher J Creevey


    Full Text Available The identification of single copy (1-to-1 orthologs in any group of organisms is important for functional classification and phylogenetic studies. The Metazoa are no exception, but only recently has there been a wide-enough distribution of taxa with sufficiently high quality sequenced genomes to gain confidence in the wide-spread single copy status of a gene.Here, we present a phylogenetic approach for identifying overlooked single copy orthologs from multigene families and apply it to the Metazoa. Using 18 sequenced metazoan genomes of high quality we identified a robust set of 1,126 orthologous groups that have been retained in single copy since the last common ancestor of Metazoa. We found that the use of the phylogenetic procedure increased the number of single copy orthologs found by over a third more than standard taxon-count approaches. The orthologs represented a wide range of functional categories, expression profiles and levels of divergence.To demonstrate the value of our set of single copy orthologs, we used them to assess the completeness of 24 currently published metazoan genomes and 62 EST datasets. We found that the annotated genes in published genomes vary in coverage from 79% (Ciona intestinalis to 99.8% (human with an average of 92%, suggesting a value for the underlying error rate in genome annotation, and a strategy for identifying single copy orthologs in larger datasets. In contrast, the vast majority of EST datasets with no corresponding genome sequence available are largely under-sampled and probably do not accurately represent the actual genomic complement of the organisms from which they are derived.

  14. Method of identifying defective particle coatings (United States)

    Cohen, Mark E.; Whiting, Carlton D.


    A method for identifying coated particles having defective coatings desig to retain therewithin a build-up of gaseous materials including: (a) Pulling a vacuum on the particles; (b) Backfilling the particles at atmospheric pressure with a liquid capable of wetting the exterior surface of the coated particles, said liquid being a compound which includes an element having an atomic number higher than the highest atomic number of any element in the composition which forms the exterior surface of the particle coating; (c) Drying the particles; and (d) Radiographing the particles. By television monitoring, examination of the radiographs is substantially enhanced.

  15. [Identifying children at risk for cardiorespiratory arrest]. (United States)

    Carrillo Alvarez, A; Martínez Gutiérrez, A; Salvat Germán, F


    Cardiorespiratory arrest in children with severe disease does not usually present suddenly or unexpectedly but is often the result of a progressive deterioration of respiratory and/or circulatory function. Before failure of these functions occurs, there is a series of clinical signs that serve as a warning. Health professionals should not only evaluate clinical signs of respiratory and/or circulatory insufficiency but should also be able to identify these warning signs as early as possible, preferably in the compensation phase, given that the possibility that this process can be reversed by therapeutic measures decreases as the process progresses.

  16. Identifying opportunities in online-communities

    DEFF Research Database (Denmark)

    Hienerth, C.; Lettl, Christopher

    how this phenomenon - as manifested in user communities - can be used to derive deeper insights into the prominent phases of opportunity identification, evaluation and exploitation. We also outline how user communities create new avenues for empirical research on these early entrepreneurial processes......Previous research has identified innovation as a crucial prerequisite for early entrepreneurial processes. However, the nature of how innovations are developed is changing dramatically, as it is becoming increasingly open, collaborative and democratized. This paper demonstrates in conceptual terms....... Based on our analysis, we develop a set of hypotheses on how processes in user communities affect the outcome of entrepreneurial activities....

  17. Identifying variables that influence manufacturing product quality

    Directory of Open Access Journals (Sweden)

    Marek Krynke


    Full Text Available In the article a risk analysis of the production process of selected products in a plant producing votive candles was conducted. The Pareto-Lorenz diagram and FMEA method were used which indicated the most important areas affecting the production of selected elements of candles. The synthesis of intangible factors affecting production in the audited company was also carried out with particular emphasis on the operation of the production system. The factors determining the validity of studies was examined, describing the principle of BOST 14 Toyota management. The most important areas of the company were identified, positively affecting the production process.

  18. Identifying biomass fuel shortages in Sri Lanka

    Energy Technology Data Exchange (ETDEWEB)

    Howes, Michael (Sussex Univ., Brighton (UK). Inst. of Development Studies)


    This paper analyses data from the Sri Lankan Forestry Master Plan and other sources, to explore the causes of biomass shortages, and to identify the areas where interventions are likely to have most impact. Five districts, concentrated in the wet lowland and hill country zones, are found to be in overall biomass fuel deficit whilst in a further five, which include dry zone locations, fuelwood consumption exceeds potential supply, Within the area of overall deficit, poorer urban groups and rural families with no home gardens - who together comprise 15% of all households nationally - are affected most severely. Another 10% of households are likely to suffer to a lesser extent. (author).

  19. EVA: Visual Analytics to Identify Fraudulent Events. (United States)

    Leite, Roger A; Gschwandtner, Theresia; Miksch, Silvia; Kriglstein, Simone; Pohl, Margit; Gstrein, Erich; Kuntner, Johannes


    Financial institutions are interested in ensuring security and quality for their customers. Banks, for instance, need to identify and stop harmful transactions in a timely manner. In order to detect fraudulent operations, data mining techniques and customer profile analysis are commonly used. However, these approaches are not supported by Visual Analytics techniques yet. Visual Analytics techniques have potential to considerably enhance the knowledge discovery process and increase the detection and prediction accuracy of financial fraud detection systems. Thus, we propose EVA, a Visual Analytics approach for supporting fraud investigation, fine-tuning fraud detection algorithms, and thus, reducing false positive alarms.

  20. Identifying Phase Space Boundaries with Voronoi Tessellations

    CERN Document Server

    Debnath, Dipsikha; Kilic, Can; Kim, Doojin; Matchev, Konstantin T.; Yang, Yuan-Pao


    Determining the masses of new physics particles appearing in decay chains is an important and longstanding problem in high energy phenomenology. Recently it has been shown that these mass measurements can be improved by utilizing the boundary of the allowed region in the fully differentiable phase space in its full dimensionality. Here we show that the practical challenge of identifying this boundary can be solved using techniques based on the geometric properties of the cells resulting from Voronoi tessellations of the relevant data. The robust detection of such phase space boundaries in the data could also be used to corroborate a new physics discovery based on a cut-and-count analysis.

  1. Identifying QCD Transition Using Deep Learning (United States)

    Zhou, Kai; Pang, Long-gang; Su, Nan; Petersen, Hannah; Stoecker, Horst; Wang, Xin-Nian


    In this proceeding we review our recent work using supervised learning with a deep convolutional neural network (CNN) to identify the QCD equation of state (EoS) employed in hydrodynamic modeling of heavy-ion collisions given only final-state particle spectra ρ(pT, V). We showed that there is a traceable encoder of the dynamical information from phase structure (EoS) that survives the evolution and exists in the final snapshot, which enables the trained CNN to act as an effective "EoS-meter" in detecting the nature of the QCD transition.

  2. Identifying MMORPG Bots: A Traffic Analysis Approach

    Directory of Open Access Journals (Sweden)

    Wen-Chin Chen


    Full Text Available Massively multiplayer online role playing games (MMORPGs have become extremely popular among network gamers. Despite their success, one of MMORPG's greatest challenges is the increasing use of game bots, that is, autoplaying game clients. The use of game bots is considered unsportsmanlike and is therefore forbidden. To keep games in order, game police, played by actual human players, often patrol game zones and question suspicious players. This practice, however, is labor-intensive and ineffective. To address this problem, we analyze the traffic generated by human players versus game bots and propose general solutions to identify game bots. Taking Ragnarok Online as our subject, we study the traffic generated by human players and game bots. We find that their traffic is distinguishable by 1 the regularity in the release time of client commands, 2 the trend and magnitude of traffic burstiness in multiple time scales, and 3 the sensitivity to different network conditions. Based on these findings, we propose four strategies and two ensemble schemes to identify bots. Finally, we discuss the robustness of the proposed methods against countermeasures of bot developers, and consider a number of possible ways to manage the increasingly serious bot problem.

  3. Identifying dependability requirements for space software systems

    Directory of Open Access Journals (Sweden)

    Edgar Toshiro Yano


    Full Text Available Computer systems are increasingly used in space, whether in launch vehicles, satellites, ground support and payload systems. Software applications used in these systems have become more complex, mainly due to the high number of features to be met, thus contributing to a greater probability of hazards related to software faults. Therefore, it is fundamental that the specification activity of requirements have a decisive role in the effort of obtaining systems with high quality and safety standards. In critical systems like the embedded software of the Brazilian Satellite Launcher, ambiguity, non-completeness, and lack of good requirements can cause serious accidents with economic, material and human losses. One way to assure quality with safety, reliability and other dependability attributes may be the use of safety analysis techniques during the initial phases of the project in order to identify the most adequate dependability requirements to minimize possible fault or failure occurrences during the subsequent phases. This paper presents a structured software dependability requirements analysis process that uses system software requirement specifications and traditional safety analysis techniques. The main goal of the process is to help to identify a set of essential software dependability requirements which can be added to the software requirement previously specified for the system. The final results are more complete, consistent, and reliable specifications.

  4. Identifying Bitcoin users by transaction behavior (United States)

    Monaco, John V.


    Digital currencies, such as Bitcoin, offer convenience and security to criminals operating in the black marketplace. Some Bitcoin marketplaces, such as Silk Road, even claim anonymity. This claim contradicts the findings in this work, where long term transactional behavior is used to identify and verify account holders. Transaction timestamps and network properties observed over time contribute to this finding. The timestamp of each transaction is the result of many factors: the desire purchase an item, daily schedule and activities, as well as hardware and network latency. Dynamic network properties of the transaction, such as coin flow and the number of edge outputs and inputs, contribute further to reveal account identity. In this paper, we propose a novel methodology for identifying and verifying Bitcoin users based on the observation of Bitcoin transactions over time. The behavior we attempt to quantify roughly occurs in the social band of Newell's time scale. A subset of the Blockchain 230686 is taken, selecting users that initiated between 100 and 1000 unique transactions per month for at least 6 different months. This dataset shows evidence of being nonrandom and nonlinear, thus a dynamical systems approach is taken. Classification and authentication accuracies are obtained under various representations of the monthly Bitcoin samples: outgoing transactions, as well as both outgoing and incoming transactions are considered, along with the timing and dynamic network properties of transaction sequences. The most appropriate representations of monthly Bitcoin samples are proposed. Results show an inherent lack of anonymity by exploiting patterns in long-term transactional behavior.

  5. Identifying, meeting, and assessing customer expectations

    International Nuclear Information System (INIS)

    Danner, T.A.


    Maintaining proficiency in carrying out mission goals is fundamental to the success of any organization. The definitive mission of the Waste Management and Remedial Action Division (WMRAD) of Oak Ridge National Laboratory (ORNL) is open-quotes to conduct waste management activities in a compliant, publicly acceptable, technically sound, and cost-efficient mannerclose quotes. In order to effectively fulfill this mission, must meet or exceed several standards in respect to our customers. These include: (1) identifying current and future customer expectations; (2) managing our relationships with our customers; (3) ensuring our commitment to our customers; and (4) measuring our success m customer satisfaction. Our customers have a great variety of requirements and expectations. Many of these are in the form of local, state, and federal regulations and environmental standards. Others are brought to our attention through inquires made to the Department of Energy (DOE).Consumer surveys have proven to be effective tools which have been used to make improvements, enhance certain program elements, and identify beneficial areas in already existing programs. In addition, national working groups, technology transfer meetings, and manager/contractor's meeting offer excellent opportunities to assess our activities

  6. Measurements with self-identifying aerosols

    International Nuclear Information System (INIS)

    Kyle, T.; Schuster, B.G.


    The use of modern single particle detection of aerosols has made it possible to test multiple HEPA filter systems. Problems have been encountered in such tests with the background aerosol on the downstream side of the filters. Since the ducts are maintained at a negative pressure, ambient aerosols leak into the ducts and provide concentrations of particles which are comparable to the number of particles of the test aerosol passing through the filters. The background count creates an upper limit to the protection factor which can be measured. This limitation can be overcome by the use of an identifiable aerosol. The most direct method of identifying an aerosol is to use fluorescent particles, which has been done in the past. In the present case, the fluorescence of the individual particle is used, rather than dissolving the particles in solution to develop the fluorescence. Two systems based upon fluorescent solid or liquid particles are being developed. Both involve single particle detection and excitation by a portable helium-cadmium laser. The advantage of the solid particles system is the ability to capture the particles on a filter. The filter can then be dissolved and the number of particles counted and sized, since the particles do not dissolve. This also permits the use of greater sample flow rates than is possible with a real time system

  7. Identifying Functional Cysteine Residues in the Mitochondria. (United States)

    Bak, Daniel W; Pizzagalli, Mattia D; Weerapana, Eranthie


    The mitochondria are dynamic organelles that regulate oxidative metabolism and mediate cellular redox homeostasis. Proteins within the mitochondria are exposed to large fluxes in the surrounding redox environment. In particular, cysteine residues within mitochondrial proteins sense and respond to these redox changes through oxidative modifications of the cysteine thiol group. These oxidative modifications result in a loss in cysteine reactivity, which can be monitored using cysteine-reactive chemical probes and quantitative mass spectrometry (MS). Analysis of cell lysates treated with cysteine-reactive probes enable the identification of hundreds of cysteine residues, however, the mitochondrial proteome is poorly represented (proteins and suppression of mitochondrial peptide MS signals by highly abundant cytosolic peptides. Here, we apply a mitochondrial isolation and purification protocol to substantially increase coverage of the mitochondrial cysteine proteome. Over 1500 cysteine residues from ∼450 mitochondrial proteins were identified, thereby enabling interrogation of an unprecedented number of mitochondrial cysteines. Specifically, these mitochondrial cysteines were ranked by reactivity to identify hyper-reactive cysteines with potential catalytic and regulatory functional roles. Furthermore, analyses of mitochondria exposed to nitrosative stress revealed previously uncharacterized sites of protein S-nitrosation on mitochondrial proteins. Together, the mitochondrial cysteine enrichment strategy presented herein enables detailed characterization of protein modifications that occur within the mitochondria during (patho)physiological fluxes in the redox environment.

  8. Identifying barriers to Muslim integration in France. (United States)

    Adida, Claire L; Laitin, David D; Valfort, Marie-Anne


    Is there a Muslim disadvantage in economic integration for second-generation immigrants to Europe? Previous research has failed to isolate the effect that religion may have on an immigrant family's labor market opportunities because other factors, such as country of origin or race, confound the result. This paper uses a correspondence test in the French labor market to identify and measure this religious effect. The results confirm that in the French labor market, anti-Muslim discrimination exists: a Muslim candidate is 2.5 times less likely to receive a job interview callback than is his or her Christian counterpart. A high-n survey reveals, consistent with expectations from the correspondence test, that second-generation Muslim households in France have lower income compared with matched Christian households. The paper thereby contributes to both substantive debates on the Muslim experience in Europe and methodological debates on how to measure discrimination. Following the National Academy of Sciences' 2001 recommendations on combining a variety of methodologies and applying them to real-world situations, this research identifies, measures, and infers consequences of discrimination based on religious affiliation, controlling for potentially confounding factors, such as race and country of origin.

  9. ABCB5 Identifies Immunoregulatory Dermal Cells

    Directory of Open Access Journals (Sweden)

    Tobias Schatton


    Full Text Available Cell-based strategies represent a new frontier in the treatment of immune-mediated disorders. However, the paucity of markers for isolation of molecularly defined immunomodulatory cell populations poses a barrier to this field. Here, we show that ATP-binding cassette member B5 (ABCB5 identifies dermal immunoregulatory cells (DIRCs capable of exerting therapeutic immunoregulatory functions through engagement of programmed cell death 1 (PD-1. Purified Abcb5+ DIRCs suppressed T cell proliferation, evaded immune rejection, homed to recipient immune tissues, and induced Tregs in vivo. In fully major-histocompatibility-complex-mismatched cardiac allotransplantation models, allogeneic DIRCs significantly prolonged allograft survival. Blockade of DIRC-expressed PD-1 reversed the inhibitory effects of DIRCs on T cell activation, inhibited DIRC-dependent Treg induction, and attenuated DIRC-induced prolongation of cardiac allograft survival, indicating that DIRC immunoregulatory function is mediated, at least in part, through PD-1. Our results identify ABCB5+ DIRCs as a distinct immunoregulatory cell population and suggest promising roles of this expandable cell subset in cellular immunotherapy.

  10. Identifying the immunomodulatory components of helminths. (United States)

    Shepherd, C; Navarro, S; Wangchuk, P; Wilson, D; Daly, N L; Loukas, A


    Immunomodulatory components of helminths offer great promise as an entirely new class of biologics for the treatment of inflammatory diseases. Here, we discuss the emerging themes in helminth-driven immunomodulation in the context of therapeutic drug discovery. We broadly define the approaches that are currently applied by researchers to identify these helminth molecules, highlighting key areas of potential exploitation that have been mostly neglected thus far, notably small molecules. Finally, we propose that the investigation of immunomodulatory compounds will enable the translation of current and future research efforts into potential treatments for autoimmune and allergic diseases, while at the same time yielding new insights into the molecular interface of host-parasite biology. © 2015 John Wiley & Sons Ltd.

  11. Identifying States of a Financial Market (United States)

    Münnix, Michael C.; Shimada, Takashi; Schäfer, Rudi; Leyvraz, Francois; Seligman, Thomas H.; Guhr, Thomas; Stanley, H. Eugene


    The understanding of complex systems has become a central issue because such systems exist in a wide range of scientific disciplines. We here focus on financial markets as an example of a complex system. In particular we analyze financial data from the S&P 500 stocks in the 19-year period 1992-2010. We propose a definition of state for a financial market and use it to identify points of drastic change in the correlation structure. These points are mapped to occurrences of financial crises. We find that a wide variety of characteristic correlation structure patterns exist in the observation time window, and that these characteristic correlation structure patterns can be classified into several typical ``market states''. Using this classification we recognize transitions between different market states. A similarity measure we develop thus affords means of understanding changes in states and of recognizing developments not previously seen.

  12. Identifying states of a financial market. (United States)

    Münnix, Michael C; Shimada, Takashi; Schäfer, Rudi; Leyvraz, Francois; Seligman, Thomas H; Guhr, Thomas; Stanley, H Eugene


    The understanding of complex systems has become a central issue because such systems exist in a wide range of scientific disciplines. We here focus on financial markets as an example of a complex system. In particular we analyze financial data from the S&P 500 stocks in the 19-year period 1992-2010. We propose a definition of state for a financial market and use it to identify points of drastic change in the correlation structure. These points are mapped to occurrences of financial crises. We find that a wide variety of characteristic correlation structure patterns exist in the observation time window, and that these characteristic correlation structure patterns can be classified into several typical "market states". Using this classification we recognize transitions between different market states. A similarity measure we develop thus affords means of understanding changes in states and of recognizing developments not previously seen.

  13. Machine learning for identifying botnet network traffic

    DEFF Research Database (Denmark)

    Stevanovic, Matija; Pedersen, Jens Myrup


    . Due to promise of non-invasive and resilient detection, botnet detection based on network traffic analysis has drawn a special attention of the research community. Furthermore, many authors have turned their attention to the use of machine learning algorithms as the mean of inferring botnet......-related knowledge from the monitored traffic. This paper presents a review of contemporary botnet detection methods that use machine learning as a tool of identifying botnet-related traffic. The main goal of the paper is to provide a comprehensive overview on the field by summarizing current scientific efforts....... The contribution of the paper is three-fold. First, the paper provides a detailed insight on the existing detection methods by investigating which bot-related heuristic were assumed by the detection systems and how different machine learning techniques were adapted in order to capture botnet-related knowledge...

  14. Identifying modular relations in complex brain networks

    DEFF Research Database (Denmark)

    Andersen, Kasper Winther; Mørup, Morten; Siebner, Hartwig


    and obtains comparable reproducibility and predictability. For resting state functional magnetic resonance imaging data from 30 healthy controls the IRM model is also superior to the two simpler alternatives, suggesting that brain networks indeed exhibit universal complex relational structure......We evaluate the infinite relational model (IRM) against two simpler alternative nonparametric Bayesian models for identifying structures in multi subject brain networks. The models are evaluated for their ability to predict new data and infer reproducible structures. Prediction and reproducibility...... are measured within the data driven NPAIRS split-half framework. Using synthetic data drawn from each of the generative models we show that the IRM model outperforms the two competing models when data contain relational structure. For data drawn from the other two simpler models the IRM does not overfit...

  15. Identifying Multiquark Hadrons from Heavy Ion Collisions

    International Nuclear Information System (INIS)

    Cho, Sungtae; Furumoto, Takenori; Yazaki, Koichi; Hyodo, Tetsuo; Jido, Daisuke; Ohnishi, Akira; Ko, Che Ming; Lee, Su Houng; Nielsen, Marina; Sekihara, Takayasu; Yasui, Shigehiro


    Identifying hadronic molecular states and/or hadrons with multiquark components either with or without exotic quantum numbers is a long-standing challenge in hadronic physics. We suggest that studying the production of these hadrons in relativistic heavy ion collisions offers a promising resolution to this problem as yields of exotic hadrons are expected to be strongly affected by their structures. Using the coalescence model for hadron production, we find that, compared to the case of a nonexotic hadron with normal quark numbers, the yield of an exotic hadron is typically an order of magnitude smaller when it is a compact multiquark state and a factor of 2 or more larger when it is a loosely bound hadronic molecule. We further find that some of the newly proposed heavy exotic states could be produced and realistically measured in these experiments.

  16. Identifying people from gait pattern with accelerometers (United States)

    Ailisto, Heikki J.; Lindholm, Mikko; Mantyjarvi, Jani; Vildjiounaite, Elena; Makela, Satu-Marja


    Protecting portable devices is becoming more important, not only because of the value of the devices themselves, but for the value of the data in them and their capability for transactions, including m-commerce and m-banking. An unobtrusive and natural method for identifying the carrier of portable devices is presented. The method uses acceleration signals produced by sensors embedded in the portable device. When the user carries the device, the acceleration signal is compared with the stored template signal. The method consists of finding individual steps, normalizing and averaging them, aligning them with the template and computing cross-correlation, which is used as a measure of similarity. Equal Error Rate of 6.4% is achieved in tentative experiments with 36 test subjects.

  17. Identifying Biases in Dust Source Functions (United States)

    Evan, A. T.; Wang, W.; Zhao, C.


    The Sahara is the largest desert in the world and accounts for more than 50% of global dust emission. However, it is difficult to identify dust source regions as the Sahara is vastly uninhabited. In order to model North African dust, previous works have used satellite data to construct so-called dust source functions. Here we examine such dust source function using output from multi-year runs with the Weather Research and Forecasting with Chemistry (WRF-Chem) model. We find that dust source functions based on satellite data overestimate DOD in the Sahel and the western Sahara region. To eliminate the biases of the dust source function due to advection, we develop a new source function using DOD in the lowest 1 km from the model. This work suggests that dust source functions constructed with satellite retrievlas of optical depth may overestimate dust emission in the downwind regions and DOD may not be a good proxy for the source function.

  18. De-identifying an EHR Database

    DEFF Research Database (Denmark)

    Lauesen, Søren; Pantazos, Kostas; Lippert, Søren


    Abstract. Electronic health records (EHR) contain a large amount of structured data and free text. Exploring and sharing clinical data can improve healthcare and facilitate the development of medical software. However, revealing confidential information is against ethical principles and laws. We de......-identified a Danish EHR database with 437,164 patients. The goal was to generate a version with real medical records, but related to artificial persons. We developed a de-identification algorithm that uses lists of named entities, simple language analysis, and special rules. Our algorithm consists of 3 steps: collect...... of anonymity, readability and correctness (F-measure of 95%). The algorithm has to be adjusted for each culture, language and database....

  19. Identifying financial crises in real time (United States)

    da Fonseca, Eder Lucio; Ferreira, Fernando F.; Muruganandam, Paulsamy; Cerdeira, Hilda A.


    Following the thermodynamic formulation of a multifractal measure that was shown to enable the detection of large fluctuations at an early stage, here we propose a new index which permits us to distinguish events like financial crises in real time. We calculate the partition function from which we can obtain thermodynamic quantities analogous to the free energy and specific heat. The index is defined as the normalized energy variation and it can be used to study the behavior of stochastic time series, such as financial market daily data. Famous financial market crashes-Black Thursday (1929), Black Monday (1987) and the subprime crisis (2008)-are identified with clear and robust results. The method is also applied to the market fluctuations of 2011. From these results it appears as if the apparent crisis of 2011 is of a different nature to the other three. We also show that the analysis has forecasting capabilities.

  20. Method of identifying features in indexed data (United States)

    Jarman, Kristin H [Richland, WA; Daly, Don Simone [Richland, WA; Anderson, Kevin K [Richland, WA; Wahl, Karen L [Richland, WA


    The present invention is a method of identifying features in indexed data, especially useful for distinguishing signal from noise in data provided as a plurality of ordered pairs. Each of the plurality of ordered pairs has an index and a response. The method has the steps of: (a) providing an index window having a first window end located on a first index and extending across a plurality of indices to a second window end; (b) selecting responses corresponding to the plurality of indices within the index window and computing a measure of dispersion of the responses; and (c) comparing the measure of dispersion to a dispersion critical value. Advantages of the present invention include minimizing signal to noise ratio, signal drift, varying baseline signal and combinations thereof.

  1. Identifying driver mutations in sequenced cancer genomes

    DEFF Research Database (Denmark)

    Raphael, Benjamin J; Dobson, Jason R; Oesper, Layla


    High-throughput DNA sequencing is revolutionizing the study of cancer and enabling the measurement of the somatic mutations that drive cancer development. However, the resulting sequencing datasets are large and complex, obscuring the clinically important mutations in a background of errors, noise......, and random mutations. Here, we review computational approaches to identify somatic mutations in cancer genome sequences and to distinguish the driver mutations that are responsible for cancer from random, passenger mutations. First, we describe approaches to detect somatic mutations from high-throughput DNA...... sequencing data, particularly for tumor samples that comprise heterogeneous populations of cells. Next, we review computational approaches that aim to predict driver mutations according to their frequency of occurrence in a cohort of samples, or according to their predicted functional impact on protein...

  2. Identifying Relevant Studies in Software Engineering

    DEFF Research Database (Denmark)

    Zhang, He; Ali Babar, Muhammad; Tell, Paolo


    Context: Systematic literature review (SLR) has become an important research methodology in software engineering since the introduction of evidence-based software engineering (EBSE) in 2004. One critical step in applying this methodology is to design and execute appropriate and effective search....... Objective: The main objective of the research reported in this paper is to improve the search step of undertaking SLRs in software engineering (SE) by devising and evaluating systematic and practical approaches to identifying relevant studies in SE. Method: We have systematically selected and analytically...... serve as a supplement to the guidelines for SLRs in EBSE. We plan to further evaluate the proposed approach using a series of case studies on varying research topics in SE....

  3. Strategic planning: Identifying organization information requirements

    Energy Technology Data Exchange (ETDEWEB)

    Moise, C.S.


    Historically, information resource management has been left to the ``data processing`` arm of the organization. With technological movements away from centralized mainframe-based information processing toward distributed client/server-based information processing, almost every part of an organization is becoming more involved with the information technology itself, and certainly more involved with budgeting for the technology. However, users and buyers of information technology frequently remain dependent upon the information systems department for planning what users need and should buy. This paper reviews techniques for identifying requirements throughout an organization and structuring information resources to meet organizational needs. This will include basing information resource needs on meeting business needs, utilizing ``internal`` and ``external`` information resource planners, using information mapping, assessing information resources, and developing partnerships.

  4. High-PT Physics with Identified Particles

    Energy Technology Data Exchange (ETDEWEB)

    Fries, R.; Liu, W.


    The suppression of high-P{sub T} particles in heavy ion collisions was one of the key discoveries at the Relativistic Heavy Ion Collider. This is usually parameterized by the average rate of momentum-transfer squared to this particle, {cflx q}. Here we argue that measurements of identified particles at high P{sub T} can lead to complementary information about the medium. The leading particle of a jet can change its identity through interactions with the medium. Tracing such flavor conversions could allow us to constrain the mean free path. Here we review the basic concepts of flavor conversions and discuss applications to particle ratios and elliptic flow. We make a prediction that strangeness is enhanced at high P{sub T} at RHIC energies while its elliptic flow is suppressed.

  5. Diverse papillomaviruses identified in Weddell seals. (United States)

    Smeele, Zoe E; Burns, Jennifer M; Van Doorsaler, Koenraad; Fontenele, Rafaela S; Waits, Kara; Stainton, Daisy; Shero, Michelle R; Beltran, Roxanne S; Kirkham, Amy L; Berngartt, Rachel; Kraberger, Simona; Varsani, Arvind


    Papillomaviridae is a diverse family of circular, double-stranded DNA (dsDNA) viruses that infect a broad range of mammalian, avian and fish hosts. While papillomaviruses have been characterized most extensively in humans, the study of non-human papillomaviruses has contributed greatly to our understanding of their pathogenicity and evolution. Using high-throughput sequencing approaches, we identified 7 novel papillomaviruses from vaginal swabs collected from 81 adult female Weddell seals (Leptonychotes weddellii) in the Ross Sea of Antarctica between 2014-2017. These seven papillomavirus genomes were amplified from seven individual seals, and six of the seven genomes represented novel species with distinct evolutionary lineages. This highlights the diversity of papillomaviruses among the relatively small number of Weddell seal samples tested. Viruses associated with large vertebrates are poorly studied in Antarctica, and this study adds information about papillomaviruses associated with Weddell seals and contributes to our understanding of the evolutionary history of papillomaviruses.

  6. QTLminer: identifying genes regulating quantitative traits

    Directory of Open Access Journals (Sweden)

    Schughart Klaus


    Full Text Available Abstract Background Quantitative trait locus (QTL mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to hundreds of genes. To find the most promising candidate genes that regulate the trait, the biologist typically collects information from multiple resources about the genes in the QTL interval. This process is very laborious and time consuming. Results QTLminer is a bioinformatics tool that automatically performs QTL region analysis. It is available in GeneNetwork and it integrates information such as gene annotation, gene expression and sequence polymorphisms for all the genes within a given genomic interval. Conclusions QTLminer substantially speeds up discovery of the most promising candidate genes within a QTL region.

  7. Identifying links between origami and compliant mechanisms

    Directory of Open Access Journals (Sweden)

    H. C. Greenberg


    Full Text Available Origami is the art of folding paper. In the context of engineering, orimimetics is the application of folding to solve problems. Kinetic origami behavior can be modeled with the pseudo-rigid-body model since the origami are compliant mechanisms. These compliant mechanisms, when having a flat initial state and motion emerging out of the fabrication plane, are classified as lamina emergent mechanisms (LEMs. To demonstrate the feasibility of identifying links between origami and compliant mechanism analysis and design methods, four flat folding paper mechanisms are presented with their corresponding kinematic and graph models. Principles from graph theory are used to abstract the mechanisms to show them as coupled, or inter-connected, mechanisms. It is anticipated that this work lays a foundation for exploring methods for LEM synthesis based on the analogy between flat-folding origami models and linkage assembly.

  8. DNA Barcoding Identifies Illegal Parrot Trade. (United States)

    Gonçalves, Priscila F M; Oliveira-Marques, Adriana R; Matsumoto, Tania E; Miyaki, Cristina Y


    Illegal trade threatens the survival of many wild species, and molecular forensics can shed light on various questions raised during the investigation of cases of illegal trade. Among these questions is the identity of the species involved. Here we report a case of a man who was caught in a Brazilian airport trying to travel with 58 avian eggs. He claimed they were quail eggs, but authorities suspected they were from parrots. The embryos never hatched and it was not possible to identify them based on morphology. As 29% of parrot species are endangered, the identity of the species involved was important to establish a stronger criminal case. Thus, we identified the embryos' species based on the analyses of mitochondrial DNA sequences (cytochrome c oxidase subunit I gene [COI] and 16S ribosomal DNA). Embryonic COI sequences were compared with those deposited in BOLD (The Barcode of Life Data System) while their 16S sequences were compared with GenBank sequences. Clustering analysis based on neighbor-joining was also performed using parrot COI and 16S sequences deposited in BOLD and GenBank. The results, based on both genes, indicated that 57 embryos were parrots (Alipiopsitta xanthops, Ara ararauna, and the [Amazona aestiva/A. ochrocephala] complex), and 1 was an owl. This kind of data can help criminal investigations and to design species-specific anti-poaching strategies, and demonstrate how DNA sequence analysis in the identification of bird species is a powerful conservation tool. © The American Genetic Association 2015. All rights reserved. For permissions, please e-mail:

  9. Identifying crucial parameter correlations maintaining bursting activity.

    Directory of Open Access Journals (Sweden)

    Anca Doloc-Mihu


    Full Text Available Recent experimental and computational studies suggest that linearly correlated sets of parameters (intrinsic and synaptic properties of neurons allow central pattern-generating networks to produce and maintain their rhythmic activity regardless of changing internal and external conditions. To determine the role of correlated conductances in the robust maintenance of functional bursting activity, we used our existing database of half-center oscillator (HCO model instances of the leech heartbeat CPG. From the database, we identified functional activity groups of burster (isolated neuron and half-center oscillator model instances and realistic subgroups of each that showed burst characteristics (principally period and spike frequency similar to the animal. To find linear correlations among the conductance parameters maintaining functional leech bursting activity, we applied Principal Component Analysis (PCA to each of these four groups. PCA identified a set of three maximal conductances (leak current, [Formula: see text]Leak; a persistent K current, [Formula: see text]K2; and of a persistent Na+ current, [Formula: see text]P that correlate linearly for the two groups of burster instances but not for the HCO groups. Visualizations of HCO instances in a reduced space suggested that there might be non-linear relationships between these parameters for these instances. Experimental studies have shown that period is a key attribute influenced by modulatory inputs and temperature variations in heart interneurons. Thus, we explored the sensitivity of period to changes in maximal conductances of [Formula: see text]Leak, [Formula: see text]K2, and [Formula: see text]P, and we found that for our realistic bursters the effect of these parameters on period could not be assessed because when varied individually bursting activity was not maintained.

  10. Melanoma biomolecules: independently identified but functionally intertwined

    Directory of Open Access Journals (Sweden)

    Danielle Erin Dye


    Full Text Available The majority of patients diagnosed with melanoma present with thin lesions and generally these patients have a good prognosis. However, 5% of patients with early melanoma (< 1mm thick will have recurrence and die within 10 years, despite no evidence of local or metastatic spread at the time of diagnosis. Thus, there is a need for additional prognostic markers to help identify those patients that may be at risk of recurrent disease. Many studies and several meta-analyses have compared gene and protein expression in melanocytes, naevi, primary and metastatic melanoma in an attempt to find informative prognostic markers for these patients. However, although a large number of putative biomarkers have been described, few of these molecules are informative when used in isolation. The best approach is likely to involve a combination of molecules. We believe one approach could be to analyze the expression of a group of interacting proteins that regulate different aspects of the metastatic pathway. This is because a primary lesion expressing proteins involved in multiple stages of metastasis may be more likely to lead to secondary disease than one that does not. This review focuses on five putative biomarkers - melanoma cell adhesion molecule (MCAM, galectin-3 (gal-3, matrix metalloproteinase 2 (MMP-2, chondroitin sulfate proteoglycan 4 (CSPG4 and paired box 3 (PAX3. The goal is to provide context around what is known about the contribution of these biomarkers to melanoma biology and metastasis. Although each of these molecules have been independently identified as likely biomarkers, it is clear from our analyses that each are closely linked with each other, with intertwined roles in melanoma biology.

  11. Identifying osteoporotic vertebral endplate and cortex fractures. (United States)

    Wáng, Yì Xiáng J; Santiago, Fernando Ruiz; Deng, Min; Nogueira-Barbosa, Marcello H


    Osteoporosis is the most common metabolic bone disease, and vertebral fractures (VFs) are the most common osteoporotic fracture. A single atraumatic VF may lead to the diagnosis of osteoporosis. Prevalent VFs increase the risk of future vertebral and non-vertebral osteoporotic fracture independent of bone mineral density (BMD). The accurate and clear reporting of VF is essential to ensure patients with osteoporosis receive appropriate treatment. Radiologist has a vital role in the diagnosis of this disease. Several morphometrical and radiological methods for detecting osteoporotic VF have been proposed, but there is no consensus regarding the definition of osteoporotic VF. A vertebra may fracture yet not ever result in measurable changes in radiographic height or area. To overcome these difficulties, algorithm-based qualitative approach (ABQ) was developed with a focus on the identification of change in the vertebral endplate. Evidence of endplate fracture (rather than variation in vertebral shape) is the primary indicator of osteoporotic fracture according to ABQ criteria. Other changes that may mimic osteoporotic fractures should be systemically excluded. It is also possible that vertebral cortex fracture may not initially occur in endplate. Particularly, vertebral cortex fracture can occur in anterior vertebral cortex without gross vertebral deformity (VD), or fractures deform the anterior vertebral cortex without endplate disruption. This article aims to serve as a teaching material for physicians or researchers to identify vertebral endplate/cortex fracture (ECF). Emphasis is particularly dedicated to identifying ECF which may not be associated apparent vertebral body collapse. We believe a combined approach based on standardized radiologic evaluation by experts and morphometry measurement is the most appropriate approach to detect and classify VFs.

  12. Identifying osteoporotic vertebral endplate and cortex fractures (United States)

    Santiago, Fernando Ruiz; Deng, Min; Nogueira-Barbosa, Marcello H.


    Osteoporosis is the most common metabolic bone disease, and vertebral fractures (VFs) are the most common osteoporotic fracture. A single atraumatic VF may lead to the diagnosis of osteoporosis. Prevalent VFs increase the risk of future vertebral and non-vertebral osteoporotic fracture independent of bone mineral density (BMD). The accurate and clear reporting of VF is essential to ensure patients with osteoporosis receive appropriate treatment. Radiologist has a vital role in the diagnosis of this disease. Several morphometrical and radiological methods for detecting osteoporotic VF have been proposed, but there is no consensus regarding the definition of osteoporotic VF. A vertebra may fracture yet not ever result in measurable changes in radiographic height or area. To overcome these difficulties, algorithm-based qualitative approach (ABQ) was developed with a focus on the identification of change in the vertebral endplate. Evidence of endplate fracture (rather than variation in vertebral shape) is the primary indicator of osteoporotic fracture according to ABQ criteria. Other changes that may mimic osteoporotic fractures should be systemically excluded. It is also possible that vertebral cortex fracture may not initially occur in endplate. Particularly, vertebral cortex fracture can occur in anterior vertebral cortex without gross vertebral deformity (VD), or fractures deform the anterior vertebral cortex without endplate disruption. This article aims to serve as a teaching material for physicians or researchers to identify vertebral endplate/cortex fracture (ECF). Emphasis is particularly dedicated to identifying ECF which may not be associated apparent vertebral body collapse. We believe a combined approach based on standardized radiologic evaluation by experts and morphometry measurement is the most appropriate approach to detect and classify VFs. PMID:29184768

  13. Use of lice to identify cowbird hosts (United States)

    Hahn, D.C.; Price, R.D.; Osenton, P.C.


    The host specificity of avian lice (Phthiraptera) may be utilized by biologists to investigate the brood parasitism patterns of Brown-headed Cowbirds (Molothrus ater). As nestlings, brood parasites have a unique opportunity to encounter lice that are typically host specific. Lice are permanent hemimetabolic ectoparasites, a group found strictly on the body of the host, and they are transferred almost exclusively by bodily contact between hosts during care of young and at copulation. We investigated whether cowbird nestlings become infested with avian lice from their host parents and carry these lice away when they fledge, in effect bearing ectoparasite indicators of the species that raised them. The technique of examining the lice on cowbird fledglings to identify their foster parents would be much less costly than hiring a team of experts to determine parasitism patterns in the conventional way by finding hundreds of songbird nests. We examined 244 cowbird fledglings and found that they carried a rich fauna of lice representing 11 species and six genera, almost the entire spectrum of louse genera known to occur on passerines. We also examined 320 songbirds from 30 species, all known hosts of the Brown-headed Cowbird. As a group the host birds bore a diversity of louse species comparable to that on the fledgling cowbirds: 13 species of lice from seven genera. In contrast, most individual passerine host species yielded only 1 or 2 louse species, significantly fewer than the cowbird fledglings (p parasitism patterns. The incomplete state of passerine louse taxonomy requires anyone using this technique to de-louse both cowbird fledglings and local host species in order to have a reference collection of lice. Lice from cowbird fledglings can be identified by a skilled taxonomist and linked to particular host species, and the principal difficulty is the scarcity of skilled avian louse taxonomists. We also found an unusually rich louse fauna on 219 adult cowbirds, which

  14. Identifying functional decline: a methodological challenge

    Directory of Open Access Journals (Sweden)

    Grimmer K


    Full Text Available Karen Grimmer, Kate Beaton, Kevan Hendry International Centre for Allied Health Evidence, University of South Australia, Adelaide, SA, Australia Background: Functional decline (FD in older people has commonly been measured in the hospital setting with instruments which have been validated on decrease over time in capacity to undertake basic activities of daily living (ADL. In a nonhospitalized sample of older people (independently community dwelling, but potentially on the cusp of FD, it is possible that other measures could be used to predict decline. Early, accurate, and efficient identification of older community-dwelling people who are on the cusp of FD can assist in identifying appropriate interventions to slow the rate of decline. Methods: This paper reports on associations between four outcome measures which have been associated with FD (instrumental ADLs [IADLs], quality of life, hospitalizations and falls. The sample was older individuals who were discharged from one large metropolitan emergency department (ED during 2011–2012, without an inpatient admission. Results: Of 597 individuals aged 65+ who provided baseline information, 148 subjects provided four outcome measures at both 1 and 3 months follow up. Overall, approximately 24% demonstrated decreased IADL scores over the 3 months, with domains of home activities, laundry, shopping, and getting places declining the most. Over this time, 18% fell often, and 11% were consistently hospitalized. Between 1 and 3 months follow up, 41% declined in mental component scores, and 50% declined in physical component scores. Low mental and physical component quality of life scores were associated with downstream increased falls and hospitalizations, and decreased quality of life and IADLs. However, change in the four outcome measures was largely independent in factor analysis. Conclusion: Measuring the four outcome measures over 3 months post-discharge from an ED presentation, showed that

  15. Pseudonymization of patient identifiers for translational research. (United States)

    Aamot, Harald; Kohl, Christian Dominik; Richter, Daniela; Knaup-Gregori, Petra


    The usage of patient data for research poses risks concerning the patients' privacy and informational self-determination. Next-generation-sequencing technologies and various other methods gain data from biospecimen, both for translational research and personalized medicine. If these biospecimen are anonymized, individual research results from genomic research, which should be offered to patients in a clinically relevant timeframe, cannot be associated back to the individual. This raises an ethical concern and challenges the legitimacy of anonymized patient samples. In this paper we present a new approach which supports both data privacy and the possibility to give feedback to patients about their individual research results. We examined previously published privacy concepts regarding a streamlined de-pseudonymization process and a patient-based pseudonym as applicable to research with genomic data and warehousing approaches. All concepts identified in the literature review were compared to each other and analyzed for their applicability to translational research projects. We evaluated how these concepts cope with challenges implicated by personalized medicine. Therefore, both person-centricity issues and a separation of pseudonymization and de-pseudonymization stood out as a central theme in our examination. This motivated us to enhance an existing pseudonymization method regarding a separation of duties. The existing concepts rely on external trusted third parties, making de-pseudonymization a multistage process involving additional interpersonal communication, which might cause critical delays in patient care. Therefore we propose an enhanced method with an asymmetric encryption scheme separating the duties of pseudonymization and de-pseudonymization. The pseudonymization service provider is unable to conclude the patient identifier from the pseudonym, but assigns this ability to an authorized third party (ombudsman) instead. To solve person-centricity issues, a

  16. Can we identify source lithology of basalt? (United States)

    Yang, Zong-Feng; Zhou, Jun-Hong


    The nature of source rocks of basaltic magmas plays a fundamental role in understanding the composition, structure and evolution of the solid earth. However, identification of source lithology of basalts remains uncertainty. Using a parameterization of multi-decadal melting experiments on a variety of peridotite and pyroxenite, we show here that a parameter called FC3MS value (FeO/CaO-3*MgO/SiO2, all in wt%) can identify most pyroxenite-derived basalts. The continental oceanic island basalt-like volcanic rocks (MgO>7.5%) (C-OIB) in eastern China and Mongolia are too high in the FC3MS value to be derived from peridotite source. The majority of the C-OIB in phase diagrams are equilibrium with garnet and clinopyroxene, indicating that garnet pyroxenite is the dominant source lithology. Our results demonstrate that many reputed evolved low magnesian C-OIBs in fact represent primary pyroxenite melts, suggesting that many previous geological and petrological interpretations of basalts based on the single peridotite model need to be reconsidered.

  17. Process to identify and evaluate restoration options

    International Nuclear Information System (INIS)

    Strand, J.; Senner, S.; Weiner, A.; Rabinowitch, S.; Brodersen, M.; Rice, K.; Klinge, K.; MacMullin, S.; Yender, R.; Thompson, R.


    The restoration planning process has yielded a number of possible alternatives for restoring resources and services injured by the Exxon Valdez oil spill. They were developed by resource managers, scientists, and the public, taking into consideration the results of damage assessment and restoration studies and information from the scientific literature. The alternatives thus far identified include no action natural recovery, management of human uses, manipulation of resources, habitat protection and acquisition, acquisition of equivalent resources, and combinations of the above. Each alternative consists of a different mix of resource- or service-specific restoration options. To decide whether it was appropriate to spend restoration funds on a particular resource or service, first criteria had to be developed that evaluated available evidence for consequential injury and the adequacy and rate of natural recovery. Then, recognizing the range of effective restoration options, a second set of criteria was applied to determine which restoration options were the most beneficial. These criteria included technical feasibility, potential to improve the rate or degree of recovery, the relationship of expected costs to benefits, cost effectiveness, and the potential to restore the ecosystem as a whole. The restoration options considered to be most beneficial will be grouped together in several or more of the above alternatives and presented in a draft restoration plan. They will be further evaluated in a companion draft environmental impact statement

  18. Identifying Memory Allocation Patterns in HEP Software (United States)

    Kama, S.; Rauschmayr, N.


    HEP applications perform an excessive amount of allocations/deallocations within short time intervals which results in memory churn, poor locality and performance degradation. These issues are already known for a decade, but due to the complexity of software frameworks and billions of allocations for a single job, up until recently no efficient mechanism has been available to correlate these issues with source code lines. However, with the advent of the Big Data era, many tools and platforms are now available to do large scale memory profiling. This paper presents, a prototype program developed to track and identify each single (de-)allocation. The CERN IT Hadoop cluster is used to compute memory key metrics, like locality, variation, lifetime and density of allocations. The prototype further provides a web based visualization back-end that allows the user to explore the results generated on the Hadoop cluster. Plotting these metrics for every single allocation over time gives a new insight into application’s memory handling. For instance, it shows which algorithms cause which kind of memory allocation patterns, which function flow causes how many short-lived objects, what are the most commonly allocated sizes etc. The paper will give an insight into the prototype and will show profiling examples for the LHC reconstruction, digitization and simulation jobs.

  19. NASA EOSDIS Data Identifiers: Approach and System

    Directory of Open Access Journals (Sweden)

    Lalit Wanchoo


    Full Text Available NASA’s Earth Science Data and Information System (ESDIS Project began investigating the use of Digital Object Identifiers (DOIs in 2010 with the goal of assigning DOIs to various data products. These Earth science research data products produced using Earth observations and models are archived and distributed by twelve Distributed Active Archive Centers (DAACs located across the United States. Each data center serves a different Earth science discipline user community and, accordingly, has a unique approach and process for generating and archiving a variety of data products. These varied approaches present a challenge for developing a DOI solution. To address this challenge, the ESDIS Project has developed processes, guidelines, and several models for creating and assigning DOIs. Initially the DOI assignment and registration process was started as a prototype but now it is fully operational. In February 2012, the ESDIS Project started using the California Digital Library (CDL EZID for registering DOIs. The DOI assignments were initially labor-intensive. The system is now automated, and the assignments are progressing rapidly. As of February 28, 2017, over 50% of the data products at the DAACs had been assigned DOIs. Citations using the DOIs increased from about 100 to over 370 between 2015 and 2016.

  20. Identifying Coevolving Partners from Paralogous Gene Families

    Directory of Open Access Journals (Sweden)

    Chen-Hsiang Yeang


    Full Text Available Many methods have been developed to detect coevolution from aligned sequences. However, all the existing methods require a one-to-one mapping of candidate coevolving partners (nucleotides, amino acids a priori. When two families of sequences have distinct duplication and loss histories, finding the one-to-one mapping of coevolving partners can be computationally involved. We propose an algorithm to identify the coevolving partners from two families of sequences with distinct phylogenetic trees. The algorithm maps each gene tree to a reference species tree, and builds a joint state of sequence composition and assignments of coevolving partners for each species tree node. By applying dynamic programming on the joint states, the optimal assignments can be identified. Time complexity is quadratic to the size of the species tree, and space complexity is exponential to the maximum number of gene tree nodes mapped to the same species tree node. Analysis on both simulated data and Pfam protein domain sequences demonstrates that the paralog coevolution algorithm picks up the coevolving partners with 60%–88% accuracy. This algorithm extends phylogeny-based coevolutionary models and make them applicable to a wide range of problems such as predicting protein-protein, protein-DNA and DNA-RNA interactions of two distinct families of sequences.

  1. Ebola Virus Infection Modelling and Identifiability Problems

    Directory of Open Access Journals (Sweden)

    Van-Kinh eNguyen


    Full Text Available The recent outbreaks of Ebola virus (EBOV infections have underlined the impact of the virus as a major threat for human health. Due to the high biosafety classification of EBOV (level 4, basic research is very limited. Therefore, the development of new avenues of thinking to advance quantitative comprehension of the virus and its interaction with the host cells is urgently neededto tackle this lethal disease. Mathematical modelling of the EBOV dynamics can be instrumental to interpret Ebola infection kinetics on quantitative grounds. To the best of our knowledge, a mathematical modelling approach to unravel the interaction between EBOV and the host cells isstill missing. In this paper, a mathematical model based on differential equations is used to represent the basic interactions between EBOV and wild-type Vero cells in vitro. Parameter sets that represent infectivity of pathogens are estimated for EBOV infection and compared with influenza virus infection kinetics. The average infecting time of wild-type Vero cells in EBOV is slower than in influenza infection. Simulation results suggest that the slow infecting time of EBOV could be compensated by its efficient replication. This study reveals several identifiability problems and what kind of experiments are necessary to advance the quantification of EBOV infection. A first mathematical approach of EBOV dynamics and the estimation of standard parametersin viral infections kinetics is the key contribution of this work, paving the way for future modelling work on EBOV infection.

  2. Identifying New Small Proteins in Escherichia coli. (United States)

    VanOrsdel, Caitlin E; Kelly, John P; Burke, Brittany N; Lein, Christina D; Oufiero, Christopher E; Sanchez, Joseph F; Wimmers, Larry E; Hearn, David J; Abuikhdair, Fatimeh J; Barnhart, Kathryn R; Duley, Michelle L; Ernst, Sarah E G; Kenerson, Briana A; Serafin, Aubrey J; Hemm, Matthew R


    The number of small proteins (SPs) encoded in the Escherichia coli genome is unknown, as current bioinformatics and biochemical techniques make short gene and small protein identification challenging. One method of small protein identification involves adding an epitope tag to the 3' end of a short open reading frame (sORF) on the chromosome, with synthesis confirmed by immunoblot assays. In this study, this strategy was used to identify new E. coli small proteins, tagging 80 sORFs in the E. coli genome, and assayed for protein synthesis. The selected sORFs represent diverse sequence characteristics, including degrees of sORF conservation, predicted transmembrane domains, sORF direction with respect to flanking genes, ribosome binding site (RBS) prediction, and ribosome profiling results. Of 80 sORFs, 36 resulted in encoded synthesized proteins-a 45% success rate. Modeling of detected versus non-detected small proteins analysis showed predictions based on RBS prediction, transcription data, and ribosome profiling had statistically-significant correlation with protein synthesis; however, there was no correlation between current sORF annotation and protein synthesis. These results suggest substantial numbers of small proteins remain undiscovered in E. coli, and existing bioinformatics techniques must continue to improve to facilitate identification. © 2018 The Authors. Proteomics Published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim, Towson University.

  3. Identifying pathways affected by cancer mutations. (United States)

    Iengar, Prathima


    Mutations in 15 cancers, sourced from the COSMIC Whole Genomes database, and 297 human pathways, arranged into pathway groups based on the processes they orchestrate, and sourced from the KEGG pathway database, have together been used to identify pathways affected by cancer mutations. Genes studied in ≥15, and mutated in ≥10 samples of a cancer have been considered recurrently mutated, and pathways with recurrently mutated genes have been considered affected in the cancer. Novel doughnut plots have been presented which enable visualization of the extent to which pathways and genes, in each pathway group, are targeted, in each cancer. The 'organismal systems' pathway group (including organism-level pathways; e.g., nervous system) is the most targeted, more than even the well-recognized signal transduction, cell-cycle and apoptosis, and DNA repair pathway groups. The important, yet poorly-recognized, role played by the group merits attention. Pathways affected in ≥7 cancers yielded insights into processes affected. Copyright © 2017 Elsevier Inc. All rights reserved.

  4. Identifying a new particle with jet substructures

    International Nuclear Information System (INIS)

    Han, Chengcheng; Kim, Doojin; Kim, Minho; Postech, Pohang


    Here, we investigate a potential of determining properties of a new heavy resonance of mass O(1)TeV which decays to collimated jets via heavy Standard Model intermediary states, exploiting jet substructure techniques. Employing the Z gauge boson as a concrete example for the intermediary state, we utilize a "merged jet" defined by a large jet size to capture the two quarks from its decay. The use of the merged jet bene ts the identification of a Z-induced jet as a single, reconstructed object without any combinatorial ambiguity. We also find that jet substructure procedures may enhance features in some kinematic observables formed with subjet four-momenta extracted from a merged jet. This observation motivates us to feed subjet momenta into the matrix elements associated with plausible hypotheses on the nature of the heavy resonance, which are further processed to construct a matrix element method (MEM)-based observable. For both moderately and highly boosted Z bosons, we demonstrate that the MEM in combination with jet substructure techniques can be a very powerful tool for identifying its physical properties. Finally, we discuss effects from choosing different jet sizes for merged jets and jet-grooming parameters upon the MEM analyses.

  5. Identifying lubricant options for compressor bearing designs (United States)

    Karnaz, J.; Seeton, C.; Dixon, L.


    Today’s refrigeration and air conditioning market is not only driven by the environmental aspects of the refrigerants, but also by the energy efficiency and reliability of system operation. Numerous types of compressor designs are used in refrigeration and air conditioning applications which means that different bearings are used; and in some cases, multiple bearing types within a single compressor. Since only one lubricant is used, it is important to try to optimize the lubricant to meet the various demands and requirements for operation. This optimization entails investigating different types of lubricant chemistries, viscosities, and various formulation options. What makes evaluating these options more challenging is the refrigerant which changes the properties of the lubricant delivered to the bearing. Once the lubricant and refrigerant interaction are understood, through various test methods, then work can start on collaborating with compressor engineers on identifying the lubricant chemistry and formulation options. These interaction properties are important to the design engineer to make decisions on the adequacy of the lubricant before compressor tests are started. This paper will discuss the process to evaluate lubricants for various types of compressors and bearing design with focus on what’s needed for current refrigerant trends. In addition, the paper will show how the lubricant chemistry choice can be manipulated through understanding of the bearing design and knowledge of interaction with the refrigerant to maximize performance. Emphasis will be placed on evaluation of synthetic lubricants for both natural and synthetic low GWP refrigerants.

  6. Identifying Middlewares for Mashup Personal Learning Environments

    Directory of Open Access Journals (Sweden)

    Jinan Fiaidhi


    Full Text Available The common understanding of e-learning has shifted over the last decade from the traditional learning objects portals to learning paradigms that enforces constructivism, discovery learning and social collaboration. Such type of learning takes place outside the formal academic settings (e.g., seminars or lectures where a learning environment is created by using some kind of web application mashup tools. The use of these mashup tools moves the learning environment further away from being a monolithic platform towards providing an open set of learning tools, an unrestricted number of actors, and an open corpus of artifacts, either pre-existing or created by the learning process – freely combinable and utilizable by learners within their learning activities. However, collaboration, mashup and contextualization can only be supported through services, which can be created and modified dynamically based on middlewares to suit the current needs and situations of learners. This article identifies middlewares suitable for creating effective personal learning environment based on Web 2.0 mashup tools. This article also proposed a general framework for constructing such personal learning environments based on Ambient Learning realized by learning agents and the use of Enterprise Mashup servers.

  7. Identifying thermal breakdown products of thermoplastics. (United States)

    Guillemot, Marianne; Oury, Benoît; Melin, Sandrine


    Polymers processed to produce plastic articles are subjected to temperatures between 150°C and 450°C or more during overheated processing and breakdowns. Heat-based processing of this nature can lead to emission of volatile organic compounds (VOCs) into the thermoplastic processing shop. In this study, laboratory experiments, qualitative and quantitative emissions measurement in thermoplastic factories were carried out. The first step was to identify the compounds released depending on the thermoplastic nature, the temperature and the type of process. Then a thermal degradation protocol that can extrapolate the laboratory results to industry scenarios was developed. The influence of three parameters on released thermal breakdown products was studied: the sample preparation methods-manual cutting, ambient, or cold grinding-the heating rate during thermal degradation-5, 10 20, and 50°C/min-and the decomposition method-thermogravimetric analysis and pyrolysis. Laboratory results were compared to atmospheric measurements taken at 13 companies to validate the protocol and thereby ensure its representativeness of industrial thermal processing. This protocol was applied to most commonly used thermoplastics to determine their thermal breakdown products and their thermal behaviour. Emissions data collected by personal exposure monitoring and sampling at the process emission area show airborne concentrations of detected compounds to be in the range of 0-3 mg/m 3 under normal operating conditions. Laser cutting or purging operations generate higher pollution levels in particular formaldehyde which was found in some cases at a concentration above the workplace exposure limit.

  8. Identifying murder victims with endodontic radiographs (United States)

    Silva, Rhonan Ferreira; Franco, Ademir; Mendes, Solon Diego Santos Carvalho; Picoli, Fernando Fortes; Nunes, Fernando Gomes; Estrela, Carlos


    Endodontics is a special branch of dentistry constantly guided by imaging examinations. From a forensic scope, endodontics plays a valuable role providing solid antemortem (AM) radiographic evidence for comparison with postmortem findings in human identifications. This study illustrates the interface between endodontics and forensic odontology describing three cases of human identification based on radiographic endodontic records. From 2009 to 2012, three unknown male victims of murder were examined in a local Brazilian medico-legal institute to retrieve identity and potential cause of death. Specifically, when asked for AM data, a relative of the three victims provided periapical radiographs of endodontic treatments. Based on that, forensic dentists reproduced the same imaging acquisition techniques obtaining similar periapical radiographs, enabling a comparative dental identification. All the victims were positively identified based on patterns of dental morphology and treatment intervention. This study draws the attention of general and forensic dentists highlight the importance of properly recording dental treatments and searching for evidence in AM endodontic data, respectively. PMID:28123272

  9. Identifying influential neighbors in animal flocking. (United States)

    Jiang, Li; Giuggioli, Luca; Perna, Andrea; Escobedo, Ramón; Lecheval, Valentin; Sire, Clément; Han, Zhangang; Theraulaz, Guy


    Schools of fish and flocks of birds can move together in synchrony and decide on new directions of movement in a seamless way. This is possible because group members constantly share directional information with their neighbors. Although detecting the directionality of other group members is known to be important to maintain cohesion, it is not clear how many neighbors each individual can simultaneously track and pay attention to, and what the spatial distribution of these influential neighbors is. Here, we address these questions on shoals of Hemigrammus rhodostomus, a species of fish exhibiting strong schooling behavior. We adopt a data-driven analysis technique based on the study of short-term directional correlations to identify which neighbors have the strongest influence over the participation of an individual in a collective U-turn event. We find that fish mainly react to one or two neighbors at a time. Moreover, we find no correlation between the distance rank of a neighbor and its likelihood to be influential. We interpret our results in terms of fish allocating sequential and selective attention to their neighbors.

  10. Identifying influential neighbors in animal flocking.

    Directory of Open Access Journals (Sweden)

    Li Jiang


    Full Text Available Schools of fish and flocks of birds can move together in synchrony and decide on new directions of movement in a seamless way. This is possible because group members constantly share directional information with their neighbors. Although detecting the directionality of other group members is known to be important to maintain cohesion, it is not clear how many neighbors each individual can simultaneously track and pay attention to, and what the spatial distribution of these influential neighbors is. Here, we address these questions on shoals of Hemigrammus rhodostomus, a species of fish exhibiting strong schooling behavior. We adopt a data-driven analysis technique based on the study of short-term directional correlations to identify which neighbors have the strongest influence over the participation of an individual in a collective U-turn event. We find that fish mainly react to one or two neighbors at a time. Moreover, we find no correlation between the distance rank of a neighbor and its likelihood to be influential. We interpret our results in terms of fish allocating sequential and selective attention to their neighbors.

  11. Identifying User Profiles from Statistical Grouping Methods

    Directory of Open Access Journals (Sweden)

    Francisco Kelsen de Oliveira


    Full Text Available This research aimed to group users into subgroups according to their levels of knowledge about technology. Statistical hierarchical and non-hierarchical clustering methods were studied, compared and used in the creations of the subgroups from the similarities of the skill levels with these users’ technology. The research sample consisted of teachers who answered online questionnaires about their skills with the use of software and hardware with educational bias. The statistical methods of grouping were performed and showed the possibilities of groupings of the users. The analyses of these groups allowed to identify the common characteristics among the individuals of each subgroup. Therefore, it was possible to define two subgroups of users, one with skill in technology and another with skill with technology, so that the partial results of the research showed two main algorithms for grouping with 92% similarity in the formation of groups of users with skill with technology and the other with little skill, confirming the accuracy of the techniques of discrimination against individuals.

  12. Identifying challenges in project consultants engagement practices (United States)

    Shariffuddin, Nadia Alina Amir; Abidin, Nazirah Zainul


    Construction projects, green or conventional, involve multi-faceted disciplines engaged with the goal of delivering products i.e. building, infrastructure etc. at the best quality within stipulated budgets. For green projects, additional attention is added for environmental quality. Due to the various responsibilities and liabilities involved as well as the complexity of the construction process itself, formal engagement of multi-disciplinary professionals i.e. project consultants is required in any construction project. Poor selection of project consultants will lead to a multitude of complications resulting in delay, cost escalation, conflicts and poor quality. This paper explores the challenges that occur during the engagement of project consultants in a green project. As the engagement decision involves developers and architects, these two groups of respondents with green project backgrounds were approached qualitatively using interview technique. The challenges identified are limited experience and knowledge, consultants' fee vs. quality, green complexity, conflicts of interest, clients' extended expectation and less demand in green projects. The construction shifts to green project demands engagement of project consultants with added skills. It is expected that through the identification of challenges, better management and administration can be created which would give impact to the overall process of engagement in green projects.

  13. The Protein Identifier Cross-Referencing (PICR service: reconciling protein identifiers across multiple source databases

    Directory of Open Access Journals (Sweden)

    Leinonen Rasko


    Full Text Available Abstract Background Each major protein database uses its own conventions when assigning protein identifiers. Resolving the various, potentially unstable, identifiers that refer to identical proteins is a major challenge. This is a common problem when attempting to unify datasets that have been annotated with proteins from multiple data sources or querying data providers with one flavour of protein identifiers when the source database uses another. Partial solutions for protein identifier mapping exist but they are limited to specific species or techniques and to a very small number of databases. As a result, we have not found a solution that is generic enough and broad enough in mapping scope to suit our needs. Results We have created the Protein Identifier Cross-Reference (PICR service, a web application that provides interactive and programmatic (SOAP and REST access to a mapping algorithm that uses the UniProt Archive (UniParc as a data warehouse to offer protein cross-references based on 100% sequence identity to proteins from over 70 distinct source databases loaded into UniParc. Mappings can be limited by source database, taxonomic ID and activity status in the source database. Users can copy/paste or upload files containing protein identifiers or sequences in FASTA format to obtain mappings using the interactive interface. Search results can be viewed in simple or detailed HTML tables or downloaded as comma-separated values (CSV or Microsoft Excel (XLS files suitable for use in a local database or a spreadsheet. Alternatively, a SOAP interface is available to integrate PICR functionality in other applications, as is a lightweight REST interface. Conclusion We offer a publicly available service that can interactively map protein identifiers and protein sequences to the majority of commonly used protein databases. Programmatic access is available through a standards-compliant SOAP interface or a lightweight REST interface. The PICR

  14. The Protein Identifier Cross-Referencing (PICR) service: reconciling protein identifiers across multiple source databases. (United States)

    Côté, Richard G; Jones, Philip; Martens, Lennart; Kerrien, Samuel; Reisinger, Florian; Lin, Quan; Leinonen, Rasko; Apweiler, Rolf; Hermjakob, Henning


    Each major protein database uses its own conventions when assigning protein identifiers. Resolving the various, potentially unstable, identifiers that refer to identical proteins is a major challenge. This is a common problem when attempting to unify datasets that have been annotated with proteins from multiple data sources or querying data providers with one flavour of protein identifiers when the source database uses another. Partial solutions for protein identifier mapping exist but they are limited to specific species or techniques and to a very small number of databases. As a result, we have not found a solution that is generic enough and broad enough in mapping scope to suit our needs. We have created the Protein Identifier Cross-Reference (PICR) service, a web application that provides interactive and programmatic (SOAP and REST) access to a mapping algorithm that uses the UniProt Archive (UniParc) as a data warehouse to offer protein cross-references based on 100% sequence identity to proteins from over 70 distinct source databases loaded into UniParc. Mappings can be limited by source database, taxonomic ID and activity status in the source database. Users can copy/paste or upload files containing protein identifiers or sequences in FASTA format to obtain mappings using the interactive interface. Search results can be viewed in simple or detailed HTML tables or downloaded as comma-separated values (CSV) or Microsoft Excel (XLS) files suitable for use in a local database or a spreadsheet. Alternatively, a SOAP interface is available to integrate PICR functionality in other applications, as is a lightweight REST interface. We offer a publicly available service that can interactively map protein identifiers and protein sequences to the majority of commonly used protein databases. Programmatic access is available through a standards-compliant SOAP interface or a lightweight REST interface. The PICR interface, documentation and code examples are available at

  15. Identifying Fishes through DNA Barcodes and Microarrays. (United States)

    Kochzius, Marc; Seidel, Christian; Antoniou, Aglaia; Botla, Sandeep Kumar; Campo, Daniel; Cariani, Alessia; Vazquez, Eva Garcia; Hauschild, Janet; Hervet, Caroline; Hjörleifsdottir, Sigridur; Hreggvidsson, Gudmundur; Kappel, Kristina; Landi, Monica; Magoulas, Antonios; Marteinsson, Viggo; Nölte, Manfred; Planes, Serge; Tinti, Fausto; Turan, Cemal; Venugopal, Moleyur N; Weber, Hannes; Blohm, Dietmar


    International fish trade reached an import value of 62.8 billion Euro in 2006, of which 44.6% are covered by the European Union. Species identification is a key problem throughout the life cycle of fishes: from eggs and larvae to adults in fisheries research and control, as well as processed fish products in consumer protection. This study aims to evaluate the applicability of the three mitochondrial genes 16S rRNA (16S), cytochrome b (cyt b), and cytochrome oxidase subunit I (COI) for the identification of 50 European marine fish species by combining techniques of "DNA barcoding" and microarrays. In a DNA barcoding approach, neighbour Joining (NJ) phylogenetic trees of 369 16S, 212 cyt b, and 447 COI sequences indicated that cyt b and COI are suitable for unambiguous identification, whereas 16S failed to discriminate closely related flatfish and gurnard species. In course of probe design for DNA microarray development, each of the markers yielded a high number of potentially species-specific probes in silico, although many of them were rejected based on microarray hybridisation experiments. None of the markers provided probes to discriminate the sibling flatfish and gurnard species. However, since 16S-probes were less negatively influenced by the "position of label" effect and showed the lowest rejection rate and the highest mean signal intensity, 16S is more suitable for DNA microarray probe design than cty b and COI. The large portion of rejected COI-probes after hybridisation experiments (>90%) renders the DNA barcoding marker as rather unsuitable for this high-throughput technology. Based on these data, a DNA microarray containing 64 functional oligonucleotide probes for the identification of 30 out of the 50 fish species investigated was developed. It represents the next step towards an automated and easy-to-handle method to identify fish, ichthyoplankton, and fish products.

  16. Identifying Fishes through DNA Barcodes and Microarrays.

    Directory of Open Access Journals (Sweden)

    Marc Kochzius

    Full Text Available BACKGROUND: International fish trade reached an import value of 62.8 billion Euro in 2006, of which 44.6% are covered by the European Union. Species identification is a key problem throughout the life cycle of fishes: from eggs and larvae to adults in fisheries research and control, as well as processed fish products in consumer protection. METHODOLOGY/PRINCIPAL FINDINGS: This study aims to evaluate the applicability of the three mitochondrial genes 16S rRNA (16S, cytochrome b (cyt b, and cytochrome oxidase subunit I (COI for the identification of 50 European marine fish species by combining techniques of "DNA barcoding" and microarrays. In a DNA barcoding approach, neighbour Joining (NJ phylogenetic trees of 369 16S, 212 cyt b, and 447 COI sequences indicated that cyt b and COI are suitable for unambiguous identification, whereas 16S failed to discriminate closely related flatfish and gurnard species. In course of probe design for DNA microarray development, each of the markers yielded a high number of potentially species-specific probes in silico, although many of them were rejected based on microarray hybridisation experiments. None of the markers provided probes to discriminate the sibling flatfish and gurnard species. However, since 16S-probes were less negatively influenced by the "position of label" effect and showed the lowest rejection rate and the highest mean signal intensity, 16S is more suitable for DNA microarray probe design than cty b and COI. The large portion of rejected COI-probes after hybridisation experiments (>90% renders the DNA barcoding marker as rather unsuitable for this high-throughput technology. CONCLUSIONS/SIGNIFICANCE: Based on these data, a DNA microarray containing 64 functional oligonucleotide probes for the identification of 30 out of the 50 fish species investigated was developed. It represents the next step towards an automated and easy-to-handle method to identify fish, ichthyoplankton, and fish products.

  17. An approach to identify urban groundwater recharge

    Directory of Open Access Journals (Sweden)

    E. Vázquez-Suñé


    Full Text Available Evaluating the proportion in which waters from different origins are mixed in a given water sample is relevant for many hydrogeological problems, such as quantifying total recharge, assessing groundwater pollution risks, or managing water resources. Our work is motivated by urban hydrogeology, where waters with different chemical signature can be identified (losses from water supply and sewage networks, infiltration from surface runoff and other water bodies, lateral aquifers inflows, .... The relative contribution of different sources to total recharge can be quantified by means of solute mass balances, but application is hindered by the large number of potential origins. Hence, the need to incorporate data from a large number of conservative species, the uncertainty in sources concentrations and measurement errors. We present a methodology to compute mixing ratios and end-members composition, which consists of (i Identification of potential recharge sources, (ii Selection of tracers, (iii Characterization of the hydrochemical composition of potential recharge sources and mixed water samples, and (iv Computation of mixing ratios and reevaluation of end-members. The analysis performed in a data set from samples of the Barcelona city aquifers suggests that the main contributors to total recharge are the water supply network losses (22%, the sewage network losses (30%, rainfall, concentrated in the non-urbanized areas (17%, from runoff infiltration (20%, and the Besòs River (11%. Regarding species, halogens (chloride, fluoride and bromide, sulfate, total nitrogen, and stable isotopes (18O, 2H, and 34S behaved quite conservatively. Boron, residual alkalinity, EDTA and Zn did not. Yet, including these species in the computations did not affect significantly the proportion estimations.

  18. Identifying Hendra virus diversity in pteropid bats.

    Directory of Open Access Journals (Sweden)

    Ina Smith

    Full Text Available Hendra virus (HeV causes a zoonotic disease with high mortality that is transmitted to humans from bats of the genus Pteropus (flying foxes via an intermediary equine host. Factors promoting spillover from bats to horses are uncertain at this time, but plausibly encompass host and/or agent and/or environmental factors. There is a lack of HeV sequence information derived from the natural bat host, as previously sequences have only been obtained from horses or humans following spillover events. In order to obtain an insight into possible variants of HeV circulating in flying foxes, collection of urine was undertaken in multiple flying fox roosts in Queensland, Australia. HeV was found to be geographically widespread in flying foxes with a number of HeV variants circulating at the one time at multiple locations, while at times the same variant was found circulating at disparate locations. Sequence diversity within variants allowed differentiation on the basis of nucleotide changes, and hypervariable regions in the genome were identified that could be used to differentiate circulating variants. Further, during the study, HeV was isolated from the urine of flying foxes on four occasions from three different locations. The data indicates that spillover events do not correlate with particular HeV isolates, suggesting that host and/or environmental factors are the primary determinants of bat-horse spillover. Thus future spillover events are likely to occur, and there is an on-going need for effective risk management strategies for both human and animal health.

  19. Identifying enabling management practices for employee engagement

    Directory of Open Access Journals (Sweden)

    Marius Joubert


    Full Text Available Orientation: A currently emerging viewpoint is that today's management practices no longer add value to organisations. The focus of this article is to conduct a systematic review of the scholarly literature on management practices that could be related to employee engagement. Research purpose: This study searched for evidence in support of the notion of a management value chain, and enabling management practices within each value chain component that could relate to employee engagement. Motivation for the study: An alternative management value chain model could contribute towards a better understanding of which management practices may potentially impact employee engagement. Research design, approach, and method: This is a non-empirical (theoretical study, based on a systematic, in-depth literature review to identify the key management components and enabling practices within this proposed management value chain. Scholarly research databases were sourced for relevant peer reviewed research conducted since 1990, not excluding important contributions prior to 1990. The literature was systematically searched, selected, studied, and contextualized within this study. Main findings: Support was found for the notion of a management value chain, for enabling management practices within each proposed management value chain component, and it was also established these management practices indeed have an impact on employee engagement. Practical/managerial/implications: The possibility that management work can be presented as a generic management value chain allows managers to approach engaging management practices more systematically. Contribution/value-add: This study highlights the importance of some management practices that have never been seen as part of management work.

  20. Collecting and identifying the radioactive waste

    International Nuclear Information System (INIS)

    Dogaru, C. GH.


    The procedure 'Collecting and identifying the radioactive waste' applied by the Radioactive Waste Management Department, STDR, complies with the requirements of the competent authority concerning the radioactive source management. One of the most important tasks, requiring the application of this procedure, is collecting and identification of 'historical wastes' for which a complete book keeping does not exist from different reasons. The chapter 1 presents the procedure's goal and the chapter 2 defines the applicability field. Chapter 3 enlists the reference documents while the chapter 4 gives the definitions and abbreviations used in the procedure. Chapter 5 defines responsibilities of the operators implied in collecting, identification and characterization of the radioactive wastes, the producers of the radioactive wastes being implied. Chapter 6 gives the preliminary conditions for applying the procedure. Among these, the transport, collecting, processing, storing and characterization costs are implied, as well as the compliance with technical and different other condition. The procedure structure is presented in the chapter 7. In collecting radioactive wastes, two situations are possible: 1- the producer is able to prepare the wastes for transport and to deliver them to STDR; 2 - the wastes are received from the producer by a delegate STDR operator, properly and technically prepared. The producer must demonstrate by documents the origin and possession, analysis bulletins specifying, the radionuclides activity and measurement date, physical state and, in addition, for spent radiation sources, the series/number of the container and producer. In case the producer is not able to display all this information, the wastes are taken into custody by the STDR labs in view of their analysis. A record in writing is completed specifying the transfer of radioactive wastes from the producer to the STDR, a record which is sent to the national authority in charge with the

  1. Electroencephalographic identifiers of motor adaptation learning (United States)

    Özdenizci, Ozan; Yalçın, Mustafa; Erdoğan, Ahmetcan; Patoğlu, Volkan; Grosse-Wentrup, Moritz; Çetin, Müjdat


    Objective. Recent brain-computer interface (BCI) assisted stroke rehabilitation protocols tend to focus on sensorimotor activity of the brain. Relying on evidence claiming that a variety of brain rhythms beyond sensorimotor areas are related to the extent of motor deficits, we propose to identify neural correlates of motor learning beyond sensorimotor areas spatially and spectrally for further use in novel BCI-assisted neurorehabilitation settings. Approach. Electroencephalographic (EEG) data were recorded from healthy subjects participating in a physical force-field adaptation task involving reaching movements through a robotic handle. EEG activity recorded during rest prior to the experiment and during pre-trial movement preparation was used as features to predict motor adaptation learning performance across subjects. Main results. Subjects learned to perform straight movements under the force-field at different adaptation rates. Both resting-state and pre-trial EEG features were predictive of individual adaptation rates with relevance of a broad network of beta activity. Beyond sensorimotor regions, a parieto-occipital cortical component observed across subjects was involved strongly in predictions and a fronto-parietal cortical component showed significant decrease in pre-trial beta-powers for users with higher adaptation rates and increase in pre-trial beta-powers for users with lower adaptation rates. Significance. Including sensorimotor areas, a large-scale network of beta activity is presented as predictive of motor learning. Strength of resting-state parieto-occipital beta activity or pre-trial fronto-parietal beta activity can be considered in BCI-assisted stroke rehabilitation protocols with neurofeedback training or volitional control of neural activity for brain-robot interfaces to induce plasticity.

  2. Identifying hidden sexual bridging communities in Chicago. (United States)

    Youm, Yoosik; Mackesy-Amiti, Mary Ellen; Williams, Chyvette T; Ouellet, Lawrence J


    Bridge populations can play a central role in the spread of human immunodeficiency virus (HIV) by providing transmission links between higher and lower prevalence populations. While social network methods are well suited to the study of bridge populations, analyses tend to focus on dyads (i.e., risk between drug and/or sex partners) and ignore bridges between distinct subpopulations. This study takes initial steps toward moving the analysis of sexual network linkages beyond individual and risk group levels to a community level in which Chicago's 77 community areas are examined as subpopulations for the purpose of identifying potential bridging communities. Of particular interest are "hidden" bridging communities; that is, areas with above-average levels of sexual ties with other areas but whose below-average AIDS prevalence may hide their potential importance for HIV prevention. Data for this analysis came from the first wave of recruiting at the Chicago Sexual Acquisition and Transmission of HIV Cooperative Agreement Program site. Between August 2005 through October 2006, respondent-driven sampling was used to recruit users of heroin, cocaine, or methamphetamine, men who have sex with men regardless of drug use, the sex partners of these two groups, and sex partners of the sex partners. In this cross-sectional study of the sexual transmission of HIV, participants completed a network-focused computer-assisted self-administered interview, which included questions about the geographic locations of sexual contacts with up to six recent partners. Bridging scores for each area were determined using a matrix representing Chicago's 77 community areas and were assessed using two measures: non-redundant ties and flow betweenness. Bridging measures and acquired immunodeficiency syndrome (AIDS) case prevalence rates were plotted for each community area on charts representing four conditions: below-average bridging and AIDS prevalence, below-average bridging and above

  3. Identifying vehicle descriptions in microblogging text with the aim of reducing or predicting crime

    CSIR Research Space (South Africa)

    Featherstone, Coral


    Full Text Available contain only about 12 words. While the standard smoothing techniques become essential under these circumstances[3], data mining techniques in the microblogging realm use additional techniques that are specific to this genre in order to supplement... can also refer to images or music or any other focus of the machine learning process. What is useful here is recognising that the text of one Tweet may not necessarily be the only document that we need to focus on. We can combine Tweets with other...


    Gomes, Alexandre; Skare, Thelma Larocca; Prestes, Manoel Alberto; Costa, Maiza da Silva; Petisco, Roberta Dombroski; Ramos, Gabriela Piovezani


    Studies with latest technologies such as endoscopy with magnification and chromoendoscopy showed that various endoscopic aspects are clearly related to infection by Helicobacter pylori (HP). The description of different patterns of erythema in gastric body under magnification of images revived interest in identifying these patterns by standard endoscopy. To validate the morphologic features of gastric mucosa related to H. pylori infection gastritis allowing predictability of their diagnosis as well as proper targeting biopsies. Prospective study of 339 consecutive patients with the standard videoendoscope image analysis were obtained, recorded and stored in a program database. These images were studied with respect to the presence or absence of H. pylori, diagnosed by rapid urease test and/or by histological analysis. Were studied: a) normal mucosa appearance; b) mucosal nodularity; c) diffuse nonspecific erythema or redness (with or without edema of folds and exudate) of antrum and body; d) mosaic pattern with focal area of hyperemia; e) erythema in streaks or bands (red streak); f) elevated (raised) erosion; g) flat erosions; h) fundic gland polyps. The main exclusion criteria were the use of drugs, HP pre-treatment and other entities that could affect results. Applying the exclusion criteria, were included 170 of the 339 patients, of which 52 (30.58%) were positive for HP and 118 negative. On the positive findings, the most associated with infection were: nodularity in the antrum (26.92%); presence of raised erosion (15.38%) and mosaic mucosa in the body (21.15%). On the negative group the normal appearance of the mucosa was 66.94%; erythema in streaks or bands in 9.32%; flat erosions 11.86%; and fundic gland polyps 11.86%. Endoscopic findings are useful in the predictability of the result and in directing biopsies. The most representative form of HP related gastritis was the nodularity of the antral mucosa. The raised erosion and mucosa in mosaic in the body

  5. Negative body image and eating disorder symptomatology among young women identifying with goth subculture. (United States)

    Swami, Viren


    The present study compared the rates of negative body image and risk for disordered eating in young women who identify as part of goth subculture and a matched sample. Participants were 80 women who identified as part of goth subculture and a matched sample of 82 women from London, United Kingdom. Participants completed measures of self-ideal body size discrepancy, body appreciation, appearance investment, and eating disorder symptomatology. Between-group comparisons indicated that goth women reported significantly higher drive for thinness (d=0.51), body dissatisfaction (d=0.62), and dysfunctional appearance investment (d=0.52), as well as lower body appreciation (d=0.55), than the matched sample. Heightened expectations about appearance and self-presentation, alongside appearance competitiveness, may result in more negative body image and disordered eating in young women who identify with goth subculture, but further research is necessary on this under-studied youth subculture. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Obtaining subjects' consent to publish identifying personal information: current practices and identifying potential issues. (United States)

    Yoshida, Akiko; Dowa, Yuri; Murakami, Hiromi; Kosugi, Shinji


    In studies publishing identifying personal information, obtaining consent is regarded as necessary, as it is impossible to ensure complete anonymity. However, current journal practices around specific points to consider when obtaining consent, the contents of consent forms and how consent forms are managed have not yet been fully examined. This study was conducted to identify potential issues surrounding consent to publish identifying personal information. Content analysis was carried out on instructions for authors and consent forms developed by academic journals in four fields (as classified by Journal Citation Reports): medicine general and internal, genetics and heredity, pediatrics, and psychiatry. An online questionnaire survey of editors working for journals that require the submission of consent forms was also conducted. Instructions for authors were reviewed for 491 academic journals (132 for medicine general and internal, 147 for genetics and heredity, 100 for pediatrics, and 112 for psychiatry). Approximately 40% (203: 74 for medicine general and internal, 31 for genetics and heredity, 58 for pediatrics, and 40 for psychiatry) stated that subject consent was necessary. The submission of consent forms was required by 30% (154) of the journals studied, and 10% (50) provided their own consent forms for authors to use. Two journals mentioned that the possible effects of publication on subjects should be considered. Many journal consent forms mentioned the difficulties in ensuring complete anonymity of subjects, but few addressed the study objective, the subjects' right to refuse consent and the withdrawal of consent. The main reason for requiring the submission of consent forms was to confirm that consent had been obtained. Approximately 40% of journals required subject consent to be obtained. However, differences were observed depending on the fields. Specific considerations were not always documented. There is a need to address issues around the study

  7. Obtaining subjects’ consent to publish identifying personal information: current practices and identifying potential issues (United States)


    Background In studies publishing identifying personal information, obtaining consent is regarded as necessary, as it is impossible to ensure complete anonymity. However, current journal practices around specific points to consider when obtaining consent, the contents of consent forms and how consent forms are managed have not yet been fully examined. This study was conducted to identify potential issues surrounding consent to publish identifying personal information. Methods Content analysis was carried out on instructions for authors and consent forms developed by academic journals in four fields (as classified by Journal Citation Reports): medicine general and internal, genetics and heredity, pediatrics, and psychiatry. An online questionnaire survey of editors working for journals that require the submission of consent forms was also conducted. Results Instructions for authors were reviewed for 491 academic journals (132 for medicine general and internal, 147 for genetics and heredity, 100 for pediatrics, and 112 for psychiatry). Approximately 40% (203: 74 for medicine general and internal, 31 for genetics and heredity, 58 for pediatrics, and 40 for psychiatry) stated that subject consent was necessary. The submission of consent forms was required by 30% (154) of the journals studied, and 10% (50) provided their own consent forms for authors to use. Two journals mentioned that the possible effects of publication on subjects should be considered. Many journal consent forms mentioned the difficulties in ensuring complete anonymity of subjects, but few addressed the study objective, the subjects’ right to refuse consent and the withdrawal of consent. The main reason for requiring the submission of consent forms was to confirm that consent had been obtained. Conclusion Approximately 40% of journals required subject consent to be obtained. However, differences were observed depending on the fields. Specific considerations were not always documented. There is a need

  8. 28 CFR 22.21 - Use of identifiable data. (United States)


    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Use of identifiable data. 22.21 Section 22.21 Judicial Administration DEPARTMENT OF JUSTICE CONFIDENTIALITY OF IDENTIFIABLE RESEARCH AND STATISTICAL INFORMATION § 22.21 Use of identifiable data. Research or statistical information identifiable to...

  9. Post discharge issues identified by a call-back program: identifying improvement opportunities. (United States)

    Ojeda, Patricia I; Kara, Areeba


    The period following discharge from the hospital is one of heightened vulnerability. Discharge instructions serve as a guide during this transition. Yet, clinicians receive little feedback on the quality of this document that ties into the patients' experience. We reviewed the issues voiced by discharged patients via a call-back program and compared them to the discharge instructions they had received. At our institution, patients receive an automated call forty-eight hours following discharge inquiring about progress. If indicated by the response to the call, they are directed to a nurse who assists with problem solving. We reviewed the nursing documentation of these encounters for a period of nine months. The issues voiced were grouped into five categories: communication, medications, durable medical equipment/therapies, follow up and new or ongoing symptoms. The discharge instructions given to each patient were reviewed. We retrieved data on the number of discharges from each specialty from the hospital over the same period. A total of 592 patients voiced 685 issues. The numbers of patients discharged from medical or surgical services identified as having issues via the call-back line paralleled the proportions discharged from medical and surgical services from the hospital during the same period. Nearly a quarter of the issues discussed had been addressed in the discharge instructions. The most common category of issues was related to communication deficits including missing or incomplete information which made it difficult for the patient to enact or understand the plan of care. Medication prescription related issues were the next most common. Resource barriers and questions surrounding medications were often unaddressed. Post discharge issues affect patients discharged from all services equally. Data from call back programs may provide actionable targets for improvement, identify the inpatient team's 'blind spots' and be used to provide feedback to clinicians.

  10. Avoiding and identifying errors in health technology assessment models: qualitative study and methodological review. (United States)

    Chilcott, J; Tappenden, P; Rawdin, A; Johnson, M; Kaltenthaler, E; Paisley, S; Papaioannou, D; Shippam, A


    identifying errors; and barriers and facilitators. There was no common language in the discussion of modelling errors and there was inconsistency in the perceived boundaries of what constitutes an error. Asked about the definition of model error, there was a tendency for interviewees to exclude matters of judgement from being errors and focus on 'slips' and 'lapses', but discussion of slips and lapses comprised less than 20% of the discussion on types of errors. Interviewees devoted 70% of the discussion to softer elements of the process of defining the decision question and conceptual modelling, mostly the realms of judgement, skills, experience and training. The original focus concerned model errors, but it may be more useful to refer to modelling risks. Several interviewees discussed concepts of validation and verification, with notable consistency in interpretation: verification meaning the process of ensuring that the computer model correctly implemented the intended model, whereas validation means the process of ensuring that a model is fit for purpose. Methodological literature on verification and validation of models makes reference to the Hermeneutic philosophical position, highlighting that the concept of model validation should not be externalized from the decision-makers and the decision-making process. Interviewees demonstrated examples of all major error types identified in the literature: errors in the description of the decision problem, in model structure, in use of evidence, in implementation of the model, in operation of the model, and in presentation and understanding of results. The HTA error classifications were compared against existing classifications of model errors in the literature. A range of techniques and processes are currently used to avoid errors in HTA models: engaging with clinical experts, clients and decision-makers to ensure mutual understanding, producing written documentation of the proposed model, explicit conceptual modelling

  11. Can a structured questionnaire identify patients with reduced renal function?

    DEFF Research Database (Denmark)

    Azzouz, Manal; Rømsing, Janne; Thomsen, Henrik


    To evaluate a structured questionnaire in identifying outpatients with renal dysfunction before MRI or CT in various age groups.......To evaluate a structured questionnaire in identifying outpatients with renal dysfunction before MRI or CT in various age groups....

  12. 25 CFR 23.82 - Assistance in identifying language interpreters. (United States)


    ... 25 Indians 1 2010-04-01 2010-04-01 false Assistance in identifying language interpreters. 23.82... WELFARE ACT Assistance to State Courts § 23.82 Assistance in identifying language interpreters. Upon the... shall assist in identifying language interpreters. Such requests for assistance should be sent to the...

  13. 13 CFR 108.130 - Identified Low Income Geographic Areas. (United States)


    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Identified Low Income Geographic Areas. 108.130 Section 108.130 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NEW MARKETS... Identified Low Income Geographic Areas. A NMVC Company must identify the specific LI Areas in which it...

  14. Identifying Novice Student Programming Misconceptions and Errors from Summative Assessments (United States)

    Veerasamy, Ashok Kumar; D'Souza, Daryl; Laakso, Mikko-Jussi


    This article presents a study aimed at examining the novice student answers in an introductory programming final e-exam to identify misconceptions and types of errors. Our study used the Delphi concept inventory to identify student misconceptions and skill, rule, and knowledge-based errors approach to identify the types of errors made by novices…

  15. A Note on Name Individuation and Identifying Descriptions | Smit ...

    African Journals Online (AJOL)

    Abstract. In “Public Proper names and Idiolectical Identifying Descriptions”, Glezakos (2009) puts forward a theory concerning the role of identifying descriptions in the theory of names. Her main claim is that such identifying descriptions serve to individuate names, i.e. to make it the case that a given linguistic act containing a ...

  16. Energy expenditure in office workers with identified health risks ...

    African Journals Online (AJOL)

    Objective. To measure the daily energy expenditure in employees previously identified as having ≥2 risk factors for chronic disease, and to identify potential risk-reducing interventions for implementation within or outside the workplace. Design. A total of 122 employees with ≥2 risk factors for chronic disease identified in ...

  17. 40 CFR 174.529 - Bacillus thuringiensis modified Cry1Ab protein as identified under OECD Unique Identifier SYN... (United States)


    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Bacillus thuringiensis modified Cry1Ab... Tolerance Exemptions § 174.529 Bacillus thuringiensis modified Cry1Ab protein as identified under OECD... Bacillus thuringiensis modified Cry1Ab protein as identified under OECD Unique Identifier SYN-IR67B-1 are...

  18. Identifying DNA Methylation Features that Underlie Prostate Cancer Disparities (United States)


    Profiles Primary Aim #1: Determine if methylation profiles differ by race/ancestry Primary Aim #2: Identify ethnicity-specific markers of prostate...cancer Primary Aim #3: Identify methylation Quantitative Trait Loci In the U.S., there are pronounced racial disparities in prostate cancer incidence...vary by ethnicity and to identify ethnicity-specific methylation features of prostate cancer that could contribute the racial disparities that exist in

  19. Novel lipid constituents identified in seeds of Nigella sativa (Linn)

    International Nuclear Information System (INIS)

    Mehta, B.K.; Verma, Manjul; Gupta, Meenal


    Novel lipids were isolated from the unsaponifiable matter extracted from seeds of Nigella sativa Linn by using n-hexane. The new dienoate and two monoesters were the new lipids identified by spectral (IR, 1 H- and 13 C-NMR spectra, mass spectrum, elemental analysis) and chemical analysis. The dienoate (1) was identified as methylnonadeca-15,17-dienoate and two monoesters were identified as pentyl hexadec-12-enoate (2) and pentyl pentadec-11-enoate (3). Linoleic acid, oleic acid, β-sitosterol and stigmasterol were identified as part of the lipid structures. All compounds exhibited moderate activity against Staphylococcus aureus and poor activity against shigella spp, and Klebsiella pneumoniae. (author)

  20. Biostratigraphical, paleoecological and paleobiogeographical interest of Guembelitria species across the Cretaceous-Paleogene transition at Atlantic realm (Bidart, SW France) and comparaison with Tethys realm (United States)

    Gallala, N.; Zaghbib-Turki, D.; Turki, M. M.; Arenillas, I.; Arz, J. A.; Molina, E.


    At the Bidart section, the extinction rate at the K/Pg boundary reach about 95 % of the planktic foraminiferal species; whereas the Cretaceous survivors persisting along the Danian could be restricted to opportunist species as G. cretacea and G. cf. trifolia, and probably some generalist species of Hedbergella and Heterohelix. The Guembelitria cretacea species, present a biostratigraphical interest, and define the Guembelitria cretacea biozone of the lower Danian interval. This biozone is marked by the presence of Guembelitria cretacea, G. trifolia, Hedbergella holmdelensis, H. monmouthensis, Heterohelix punctulata, H. glabrans, H. labellosa, H. planata, H. pulchra, H. globulosa, and H. navarroensis. The ecological opportunist or disaster species Guembelitria cretacea (>63 µm) is present in very low frequencies (Caravaca sections (Spain). Like the guembelitrids, the hedbergellids species and perhaps few heterohelicids could be possible survivors.

  1. A methodology to identify the intake charge cylinder-to-cylinder distribution in turbocharged direct injection Diesel engines (United States)

    Luján, José M.; Galindo, José; Serrano, José R.; Pla, Benjamín


    Exhaust gas recirculation (EGR) is currently the most important NOx emission control system. During the last few years the EGR rate has increased progressively as pollutant emission regulations have become more restrictive. High EGR rate levels have given the effect of the unsuitable EGR and air distribution between cylinders away, which causes undesirable engine behavior. In this sense, the study of the EGR distribution between cylinders achieves high importance. However, despite the fact that the EGR is continuously under study, not many studies have been undertaken to approach its distribution between cylinders. In concordance with the aspects outlined before, the aim of this paper is to propose a methodology that permits us to identify the EGR cylinder-to-cylinder dispersion in a commercial engine. In order to achieve this objective, experimental tests have been combined with both one-dimensional and three-dimensional fluid dynamic models.

  2. Parents of Youth Who Identify as Transgender: An Exploratory Study (United States)

    Johnson, Danielle; Sikorski, Jonathon; Savage, Todd A.; Woitaszewski, Scott A.


    This article explores the experiences, perceptions, support systems, and coping strategies on which parents of youth who identify as transgender rely. Based on data gathered via interviews with parents of youth who identify as transgender and analyzed using the consensual qualitative research method, parental challenges and concerns about their…

  3. Genomic Regions Affecting Cheese Making Properties Identified in Danish Holsteins

    DEFF Research Database (Denmark)

    Gregersen, Vivi Raundahl; Bertelsen, Henriette Pasgaard; Poulsen, Nina Aagaard

    The cheese renneting process is affected by a number of factors associated to milk composition and a number of Danish Holsteins has previously been identified to have poor milk coagulation ability. Therefore, the aim of this study was to identify genomic regions affecting the technological proper...

  4. Identifiability Results for Several Classes of Linear Compartment Models. (United States)

    Meshkat, Nicolette; Sullivant, Seth; Eisenberg, Marisa


    Identifiability concerns finding which unknown parameters of a model can be estimated, uniquely or otherwise, from given input-output data. If some subset of the parameters of a model cannot be determined given input-output data, then we say the model is unidentifiable. In this work, we study linear compartment models, which are a class of biological models commonly used in pharmacokinetics, physiology, and ecology. In past work, we used commutative algebra and graph theory to identify a class of linear compartment models that we call identifiable cycle models, which are unidentifiable but have the simplest possible identifiable functions (so-called monomial cycles). Here we show how to modify identifiable cycle models by adding inputs, adding outputs, or removing leaks, in such a way that we obtain an identifiable model. We also prove a constructive result on how to combine identifiable models, each corresponding to strongly connected graphs, into a larger identifiable model. We apply these theoretical results to several real-world biological models from physiology, cell biology, and ecology.

  5. Identifying Interbank Loans, Rates, and Claims Networks from Transactional Data

    NARCIS (Netherlands)

    Leon Rincon, C.E.; Cely, Jorge; Cadena, Carlos


    We identify interbank (i.e. non-collateralized) loans from the Colombian large-value payment system by implementing Furfine’s method. After identifying interbank loans from transactional data we obtain the interbank rates and claims without relying on financial institutions’ reported data.

  6. 48 CFR 2009.570-7 - Conflicts identified after award. (United States)


    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Conflicts identified after... COMMISSION COMPETITION AND ACQUISITION PLANNING CONTRACTOR QUALIFICATIONS Organizational Conflicts of Interest 2009.570-7 Conflicts identified after award. If potential organizational conflicts of interest are...

  7. 34 CFR 5.16 - Deletion of identifying details. (United States)


    ... 34 Education 1 2010-07-01 2010-07-01 false Deletion of identifying details. 5.16 Section 5.16 Education Office of the Secretary, Department of Education AVAILABILITY OF INFORMATION TO THE PUBLIC PURSUANT TO PUB. L. 90-23 (Eff. until 7-14-10) What Records Are Available § 5.16 Deletion of identifying...

  8. 42 CFR 401.118 - Deletion of identifying details. (United States)


    ... 42 Public Health 2 2010-10-01 2010-10-01 false Deletion of identifying details. 401.118 Section 401.118 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN... Deletion of identifying details. When CMS publishes or otherwise makes available an opinion or order...

  9. 49 CFR 7.6 - Deletion of identifying detail. (United States)


    ... 49 Transportation 1 2010-10-01 2010-10-01 false Deletion of identifying detail. 7.6 Section 7.6... To Be Made Public by DOT § 7.6 Deletion of identifying detail. Whenever it is determined to be... the deletion will accompany the record published or made available for inspection. ...

  10. An Application Of Receptor Modeling To Identify Airborne Particulate ...

    African Journals Online (AJOL)

    An Application Of Receptor Modeling To Identify Airborne Particulate Sources In Lagos, Nigeria. FS Olise, OK Owoade, HB Olaniyi. Abstract. There have been no clear demarcations between industrial and residential areas of Lagos with focus on industry as the major source. There is need to identify potential source types in ...

  11. Identifying a K-10 Developmental Framework for Teaching Philosophy (United States)

    Poulton, Janette


    The intention of the study was to identify predictable opportunities for teachers to scaffold middle year students' philosophical learning. Such opportunities were identified in terms of students' readiness to learn certain behaviours in the context of a "community of inquiry". Thus it was hoped that the project would provide a useful…

  12. 75 FR 14539 - Furnishing Identifying Number of Tax Return Preparer (United States)


    ... tax return preparers and employers of tax return preparers. Estimated total annual reporting burden..., the preparer's employer, or both. Section 8246(a)(2)(D)(i) of the Small Business and Work Opportunity..., skilled, and ethical. 1. Identifying Numbers Generally Because an identifying number is unique to the...

  13. Method of identifying hairpin DNA probes by partial fold analysis (United States)

    Miller, Benjamin L [Penfield, NY; Strohsahl, Christopher M [Saugerties, NY


    Method of identifying molecular beacons in which a secondary structure prediction algorithm is employed to identify oligonucleotide sequences within a target gene having the requisite hairpin structure. Isolated oligonucleotides, molecular beacons prepared from those oligonucleotides, and their use are also disclosed.

  14. Identifying Core Concepts of Cybersecurity: Results of Two Delphi Processes (United States)

    Parekh, Geet; DeLatte, David; Herman, Geoffrey L.; Oliva, Linda; Phatak, Dhananjay; Scheponik, Travis; Sherman, Alan T.


    This paper presents and analyzes results of two Delphi processes that polled cybersecurity experts to rate cybersecurity topics based on importance, difficulty, and timelessness. These ratings can be used to identify core concepts--cross-cutting ideas that connect knowledge in the discipline. The first Delphi process identified core concepts that…

  15. Identifying child abuse through text mining and machine learning

    NARCIS (Netherlands)

    Amrit, Chintan; Paauw, Tim; Aly, Robin; Lavric, Miha


    In this paper, we describe how we used text mining and analysis to identify and predict cases of child abuse in a public health institution. Such institutions in the Netherlands try to identify and prevent different kinds of abuse. A significant part of the medical data that the institutions have on

  16. Persistent Identifiers for Data Products: Adoption, Enhancement, and Use (United States)

    Downs, R. R.; Schumacher, J.; Scialdone, J.; Hansen, M.


    Persistent identifiers offer value for science and for various science community stakeholders, such as data producers, data distributers, science article authors, scientific journal publishers, research sponsors, libraries, and affiliated institutions. However, to attain the benefits of persistent identifiers, they should be assigned to disseminated data products and included within the references reported in publications that describe the studies in which the data were used. Scientific data centers, archives, digital repositories, and other data publishers also need to determine the level of aggregation, or granularity, of data products to be assigned persistent identifiers as well as the elements to be included in the landing pages to which persistent identifiers will resolve. Similarly, policies and procedures should be clear on decisions about maintenance issues, including versioning of data products and how persistent identifiers to previous versions and new locations will be maintained. With some persistent identifiers, such as Digital Object Identifiers (DOIs), which provide capabilities to link to related identifiers of other works, decisions on the establishment of links also must be clear, including links between early versions of data products and subsequent versions, links between data products and associated documentation, and links between data products and other publications that describe the data. We describe decisions for enabling the adoption and assignment of DOIs as persistent identifiers for data products disseminated by the NASA Socioeconomic Data and Applications Center (SEDAC) along with considerations for policy decisions, testing, implementation, and enhancement. The prevalence of the adoption of DOIs for citing the use of Earth science data disseminated by SEDAC also is described to provide insight into how interdisciplinary data users have engaged in the use of DOIs within their publications along with the implications of such use.

  17. Target and identify: triazene linker helps identify azidation sites of labelled proteins via click and cleave strategy. (United States)

    Lohse, Jonas; Schindl, Alexandra; Danda, Natasha; Williams, Chris P; Kramer, Karl; Kuster, Bernhard; Witte, Martin D; Médard, Guillaume


    A method for identifying probe modification of proteins via tandem mass spectrometry was developed. Azide bearing molecules are immobilized on functionalised sepharose beads via copper catalysed Huisgen-type click chemistry and selectively released under acidic conditions by chemical cleavage of the triazene linkage. We applied this method to identify the modification site of targeted-diazotransfer on BirA.

  18. Substrate Capture Assay Using Inactive Oligopeptidases to Identify Novel Peptides. (United States)

    Rioli, Vanessa; Ferro, Emer S


    Researchers are always searching for novel biologically active molecules including peptides. With the improvement of equipment for electrospray mass spectrometry, it is now possible to identify hundreds of novel peptides in a single run. However, after identifying the peptide sequences it is expensive to synthesize all the peptides to perform biological activity assays. Here, we describe a substrate capture assay that uses inactive oligopeptidases to identify putative biologically active peptides in complexes peptide mixtures. This methodology can use any crude extracts of biological tissues or cells, with the advantage to introduce a filter (i.e., binding to an inactive oligopeptidase) as a prior step in screening to bioactive peptides.

  19. An improved anti-leech mechanism based on session identifier (United States)

    Zhang, Jianbiao; Zhu, Tong; Zhang, Han; Lin, Li


    With the rapid development of information technology and extensive requirement of network resource sharing, plenty of resource hotlinking phenomenons appear on the internet. The hotlinking problem not only harms the interests of legal websites but also leads to a great affection to fair internet environment. The anti-leech technique based on session identifier is highly secure, but the transmission of session identifier in plaintext form causes some security flaws. In this paper, a proxy hotlinking technique based on session identifier is introduced firstly to illustrate these security flaws; next, this paper proposes an improved anti-leech mechanism based on session identifier, the mechanism takes the random factor as the core and detects hotlinking request using a map table that contains random factor, user's information and time stamp; at last the paper analyzes the security of mechanism in theory. The result reveals that the improved mechanism has the merits of simple realization, high security and great flexibility.

  20. Guidance for Identifying, Selecting and Evaluating Open Literature Studies (United States)

    This guidance for Office of Pesticide Program staff will assist in their evaluation of open literature studies of pesticides. It also describes how we identify, select, and ensure that data we use in risk assessments is of sufficient scientific quality.

  1. TCGA study identifies genomic features of cervical cancer (United States)

    Investigators with The Cancer Genome Atlas (TCGA) Research Network have identified novel genomic and molecular characteristics of cervical cancer that will aid in subclassification of the disease and may help target therapies that are most appropriate for each patient.

  2. Inducing and identifying artificially-induced polyploidy in bananas ...

    African Journals Online (AJOL)

    Malbut', 'Gold', 'Lidi', and 'Thong Dok Mak' through the use of colchicine and oryzalin, and that condition was identified through stomatal analysis, flow cytometry, and chromosome counts. Shoots produced in vitro were treated with colchicine at ...

  3. Preserving Privacy by De-identifying Facial Images

    National Research Council Canada - National Science Library

    Newton, Elaine; Sweeney, Latanya; Malin, Bradley


    .... A trivial solution to de-identifying faces involves blacking out each face. This thwarts any possible face recognition, but because all facial details are obscured, the result is of limited use...

  4. Using the National Provider Identifier for Health Care... (United States)

    U.S. Department of Health & Human Services — The establishment in recent years of a National Provider Identifier (NPI) offers a new method for counting and categorizing physicians and other health care...

  5. Novel lipid constituents identified in seeds of Nigella sativa (Linn)

    Energy Technology Data Exchange (ETDEWEB)

    Mehta, B.K.; Verma, Manjul; Gupta, Meenal [Vikram University (India). School of Studies in Chemistry and Biochemistry]. E-mail:


    Novel lipids were isolated from the unsaponifiable matter extracted from seeds of Nigella sativa Linn by using n-hexane. The new dienoate and two monoesters were the new lipids identified by spectral (IR, {sup 1}H- and {sup 13}C-NMR spectra, mass spectrum, elemental analysis) and chemical analysis. The dienoate (1) was identified as methylnonadeca-15,17-dienoate and two monoesters were identified as pentyl hexadec-12-enoate (2) and pentyl pentadec-11-enoate (3). Linoleic acid, oleic acid, {beta}-sitosterol and stigmasterol were identified as part of the lipid structures. All compounds exhibited moderate activity against Staphylococcus aureus and poor activity against shigella spp, and Klebsiella pneumoniae. (author)

  6. Comparing complete and partial classification for identifying customers at risk

    NARCIS (Netherlands)

    Bloemer, J.M.M.; Brijs, T.; Swinnen, S.P.; Vanhoof, K.


    This paper evaluates complete versus partial classification for the problem of identifying customers at risk. We define customers at risk as customers reporting overall satisfaction, but these customers also possess characteristics that are strongly associated with dissatisfied customers. This

  7. Identifying learning characteristics of the gifted Students in the ...

    African Journals Online (AJOL)

    Identifying learning characteristics of the gifted Students in the Inclusive classroom among secondary schools in Nigeria: Implications for placement, instruction and counselling. MI Goshwe, ND Zachariah, NS Gutat ...

  8. Identifying victims of violence using register-based data

    DEFF Research Database (Denmark)

    Kruse, Marie; Sørensen, Jan; Brønnum-Hansen, Henrik


    AIMS: The aim of this study was twofold. Firstly we identified victims of violence in national registers and discussed strengths and weaknesses of this approach. Secondly we assessed the magnitude of violence and the characteristics of the victims using register-based data. METHODS: We used three...... nationwide registers to identify victims of violence: The National Patient Register, the Victim Statistics, and the Causes of Death Register. We merged these data and assessed the degree of overlap between data sources. We identified a reference population by selecting all individuals in Denmark over 15....... RESULTS: In 2006, 22,000 individuals were registered as having been exposed to violence. About 70% of these victims were men. Most victims were identified from emergency room contacts and police records, and few from the Causes of Death Register. There was some overlap between the two large data sources...

  9. Identifying customer-focused performance measures : final report 655. (United States)


    The Arizona Department of Transportation (ADOT) completed a comprehensive customer satisfaction : assessment in July 2009. ADOT commissioned the assessment to acquire statistically valid data from residents : and community leaders to help it identify...

  10. A novel stroke locus identified in a northern Sweden pedigree

    DEFF Research Database (Denmark)

    Janunger, T.; Nilsson-Ardnor, S.; Wiklund, P.-G.


    OBJECTIVES: The population of northern Sweden is characterized by reduced genetic diversity and a high incidence of stroke. We sought to reduce genetic variation further, using genealogic analysis in a set of nuclear families affected by stroke, and we subsequently performed a genome-wide scan...... to identify novel stroke susceptibility loci. METHODS: Through genealogy, 7 nuclear families with a common ancestor, connected over 8 generations, were identified. A genome-wide scan using 449 microsatellite markers was performed with subsequent haplotype analyses. RESULTS: A maximum allele-sharing lod score...... of 4.81 on chromosome 9q31-q33 was detected. Haplotype analysis identified a common 2.2-megabase interval in the chromosomal region in 4 of the nuclear families, where an overrepresentation of intracerebral hemorrhage was observed. CONCLUSIONS: We have identified a novel susceptibility locus for stroke...

  11. Identifying factors affecting destination choice of medical tourists: a ...

    African Journals Online (AJOL)

    medical tourism”, has emerged as a new source of competitive advantage all over the world. The present study seeks to identify the factors that affect destination choice of medical tourists. Methods: We systematically searched relevant databases ...

  12. Identifying salt stress-responsive transcripts from Roselle ( Hibiscus ...

    African Journals Online (AJOL)

    Hibiscus sabdariffa L.). Identifying the potentially novel transcripts responsible for salt stress tolerance in roselle will increase knowledge of the molecular mechanism underlying salt stress responses. In this study, differential display reverse ...

  13. Practical identifiability analysis of a minimal cardiovascular system model. (United States)

    Pironet, Antoine; Docherty, Paul D; Dauby, Pierre C; Chase, J Geoffrey; Desaive, Thomas


    Parameters of mathematical models of the cardiovascular system can be used to monitor cardiovascular state, such as total stressed blood volume status, vessel elastance and resistance. To do so, the model parameters have to be estimated from data collected at the patient's bedside. This work considers a seven-parameter model of the cardiovascular system and investigates whether these parameters can be uniquely determined using indices derived from measurements of arterial and venous pressures, and stroke volume. An error vector defined the residuals between the simulated and reference values of the seven clinically available haemodynamic indices. The sensitivity of this error vector to each model parameter was analysed, as well as the collinearity between parameters. To assess practical identifiability of the model parameters, profile-likelihood curves were constructed for each parameter. Four of the seven model parameters were found to be practically identifiable from the selected data. The remaining three parameters were practically non-identifiable. Among these non-identifiable parameters, one could be decreased as much as possible. The other two non-identifiable parameters were inversely correlated, which prevented their precise estimation. This work presented the practical identifiability analysis of a seven-parameter cardiovascular system model, from limited clinical data. The analysis showed that three of the seven parameters were practically non-identifiable, thus limiting the use of the model as a monitoring tool. Slight changes in the time-varying function modeling cardiac contraction and use of larger values for the reference range of venous pressure made the model fully practically identifiable. Copyright © 2017. Published by Elsevier B.V.

  14. A Note on the Identifiability of Generalized Linear Mixed Models

    DEFF Research Database (Denmark)

    Labouriau, Rodrigo


    I present here a simple proof that, under general regularity conditions, the standard parametrization of generalized linear mixed model is identifiable. The proof is based on the assumptions of generalized linear mixed models on the first and second order moments and some general mild regularity ...... conditions, and, therefore, is extensible to quasi-likelihood based generalized linear models. In particular, binomial and Poisson mixed models with dispersion parameter are identifiable when equipped with the standard parametrization...

  15. Communication difficulties in children identified with psychiatric problems


    Helland, Wenche Andersen


    Several studies have pointed to an overlap between different developmental psychopathological conditions and language impairments, and difficulties with communication have been identified in children of various diagnostic backgrounds. This thesis is based on three empirical studies, and the purposes are to investigate communication difficulties as reported by parents, in children identified with psychiatric problems as well as to evaluate a Norwegian adaptation of the Children’...

  16. The valuation of nursing begins with identifying value drivers. (United States)

    Rutherford, Marcella M


    Adequate investment in a profession links to its ability to define and document its value. This requires identifying those elements or value drivers that demonstrate its worth. To completely identify nursing's value drivers requires meshing the economic, technical, and caring aspects of its profession. Nursing's valuation includes assessing nursing's tangible and intangible assets and documenting these assets. This information communicates nursing's worth and ensures adequate economic investment in its services.

  17. Determinants of top management's capability to identify core employees


    García-Carbonell, Natalia; Martín-Alcázar, Fernando; Sánchez-Gardey, Gonzalo


    Despite the increasing academic interest, the human resource management formulation process still remains unclear. Building on human capital and talent management literatures, this study investigates how top management teams identify critical human resources. The proposed model explores how top management teams’ ability to identify core employees is conditioned by two human capital attributes of their members (cognitive skills and value orientation). The empirical analysis developed confirms ...

  18. Improving applicant selection: identifying qualities of the unsuccessful otolaryngology resident. (United States)

    Badran, Karam W; Kelley, Kanwar; Conderman, Christian; Mahboubi, Hossein; Armstrong, William B; Bhandarkar, Naveen D


    To identify the prevalence and management of problematic residents. Additionally, we hope to identify the factors associated with successful remediation of unsuccessful otolaryngology residents. Self-reported Internet and paper-based survey. An anonymous survey was distributed to 152 current and former program directors (PDs) in 2012. The factors associated with unsuccessful otolaryngology residents and those associated with the successful remediation of problematic residents were investigated. An unsuccessful resident is defined as one who quit or was removed from the program for any reason, or one whose actions resulted in criminal action or citation against their medical license after graduation from residency. Remediation is defined as an individualized program implemented to correct documented weaknesses. The overall response rate was 26% (40 PDs). Seventy-three unsuccessful or problematic residents were identified. Sixty-six problematic or unsuccessful residents were identified during residency, with 58 of 66 (88%) undergoing remediation. Thirty-one (47%) residents did not graduate. The most commonly identified factors of an unsuccessful resident were: change in specialty (21.5%), interpersonal and communication skills with health professionals (13.9%), and clinical judgment (10.1%). Characteristics of those residents who underwent successful remediation include: poor performance on in-training examination (17%, P otolaryngology PDs in this sample identified at least one unsuccessful resident. Improved methods of applicant screening may assist in optimizing otolaryngology resident selection. © 2014 The American Laryngological, Rhinological and Otological Society, Inc.


    Directory of Open Access Journals (Sweden)

    Anand P


    Full Text Available BACKGROUND: Dementia is an emerging medico social problem affecting elderly, and poses a challenge to clinician and caregivers. It is usually identified in late stage where management becomes difficult. AIM: The aim of camp was to identify dementia in elderly population participating in screening camp. MATERIAL AND METHODS : The geriatric clinic and department of psychiatry jointly organised screening camp to detect dementia in elderly for five days in September 2014 to commemorate world Alzheimer’s day. The invitation regarding camp was sent to all senio r citizen forums and also published in leading Kannada daily newspaper. Mini Mental Status Examination and Diagnostic and Statistical Manual of Mental Disorders, 4 th edition criteria (DSM IV was used to identify dementia. RESULTS: Elderly male participate d in camp in more number than females and dementia was identified in 36% elderly with education less than 9 th standard. Dementia was found in 18% in our study population. CONCLUSION: The camp help identify elderly suffering from dementia and also created a wareness about it. Hypertension and diabetes mellitus were common co morbidity in study population. Our study suggested organising screening camp will help identify elderly living with dementia.

  20. Utility of kindergarten teacher judgments in identifying early learning problems. (United States)

    Taylor, H G; Anselmo, M; Foreman, A L; Schatschneider, C; Angelopoulos, J


    Most existing research on early identification of learning difficulties has examined the validity of methods for predicting future academic problems. The present study focused instead on the sensitivity of kindergarten teachers to learning problems in their students and on the continuity of teacher-identified problems over time. To identify early learning problems, kindergarten teachers in a suburban school district rated student progress toward six academic objectives as satisfactory or unsatisfactory. Twenty percent of the district's 303 kindergarten children received unsatisfactory ratings in at least one area. Thirty-eight of these children (identified group) were matched to 34 children with satisfactory ratings in all areas (nonidentified group). Results of testing conducted during kindergarten revealed poorer academic achievement in identified children than in nonidentified children. Children from the identified group also performed more poorly than children from the nonidentified group on tests of phonological processing and working memory/executive function and were rated by teachers as having more behavior and attention problems and lower social competence. Follow-up of the sample to first grade documented continued learning problems in the identified group. These findings support the use of teacher judgements in early detection of learning problems and argue against reliance on discrepancy criteria.

  1. Identifying Cancer Driver Genes Using Replication-Incompetent Retroviral Vectors

    Directory of Open Access Journals (Sweden)

    Victor M. Bii


    Full Text Available Identifying novel genes that drive tumor metastasis and drug resistance has significant potential to improve patient outcomes. High-throughput sequencing approaches have identified cancer genes, but distinguishing driver genes from passengers remains challenging. Insertional mutagenesis screens using replication-incompetent retroviral vectors have emerged as a powerful tool to identify cancer genes. Unlike replicating retroviruses and transposons, replication-incompetent retroviral vectors lack additional mutagenesis events that can complicate the identification of driver mutations from passenger mutations. They can also be used for almost any human cancer due to the broad tropism of the vectors. Replication-incompetent retroviral vectors have the ability to dysregulate nearby cancer genes via several mechanisms including enhancer-mediated activation of gene promoters. The integrated provirus acts as a unique molecular tag for nearby candidate driver genes which can be rapidly identified using well established methods that utilize next generation sequencing and bioinformatics programs. Recently, retroviral vector screens have been used to efficiently identify candidate driver genes in prostate, breast, liver and pancreatic cancers. Validated driver genes can be potential therapeutic targets and biomarkers. In this review, we describe the emergence of retroviral insertional mutagenesis screens using replication-incompetent retroviral vectors as a novel tool to identify cancer driver genes in different cancer types.

  2. Identifying risk: a comparison of risk between heterosexual-identifying bisexual men and other bisexual men in Vientiane, Laos. (United States)

    Bowring, Anna; van Gemert, C; Vongsaiya, K; Hughes, C; Sihavong, A; Phimphachanh, C; Chanlivong, N; Toole, M; Hellard, M


    Men who have sex with men are a priority population for HIV control in Laos, but encompass men diverse in sexual orientation, gender identification, and behavior. Behaviorally bisexual men and their sexual partners were recruited in Vientiane, Laos, in 2010 using modified snowball sampling. Heterosexual-identifying bisexual men identified as exclusively/predominantly heterosexual and other bisexual men identified as bisexual or predominantly/exclusively homosexual. Sixty (68%) heterosexual-identifying and 38 (32%) other bisexual men were recruited; the median number of sex partners in the past year was eight and seven, respectively. Consistent condom use was low with regular (7%) and casual (35%) partners and did not differ by identity. More heterosexual-identifying (53%) than other bisexual (29%) men reported weekly alcohol consumption. Twelve (20%) heterosexual-identifying and 15 (54%) other bisexual men correctly answered all HIV-knowledge questions. High-risk behaviors for STI and HIV transmission were common. Targeted HIV prevention initiatives are needed, particularly to reach heterosexual-identifying bisexual men.

  3. Integrating subpathway analysis to identify candidate agents for hepatocellular carcinoma

    Directory of Open Access Journals (Sweden)

    Wang J


    Full Text Available Jiye Wang,1 Mi Li,2 Yun Wang,3 Xiaoping Liu4 1The Criminal Science and Technology Department, Zhejiang Police College, Hangzhou, Zhejiang Province, 2Department of Nursing, Shandong College of Traditional Chinese Medicine College, Yantai, Shandong Province, 3Office Department of Gastroenterology, The First Affiliated Hospital of Xi’an Jiao Tong University, Xi’an, Shanxi Province, 4Key Laboratory of Systems Biology, Shanghai Institutes for Biological Sciences, Shanghai, People’s Republic of China Abstract: Hepatocellular carcinoma (HCC is the second most common cause of cancer-associated death worldwide, characterized by a high invasiveness and resistance to normal anticancer treatments. The need to develop new therapeutic agents for HCC is urgent. Here, we developed a bioinformatics method to identify potential novel drugs for HCC by integrating HCC-related and drug-affected subpathways. By using the RNA-seq data from the TCGA (The Cancer Genome Atlas database, we first identified 1,763 differentially expressed genes between HCC and normal samples. Next, we identified 104 significant HCC-related subpathways. We also identified the subpathways associated with small molecular drugs in the CMap database. Finally, by integrating HCC-related and drug-affected subpathways, we identified 40 novel small molecular drugs capable of targeting these HCC-involved subpathways. In addition to previously reported agents (ie, calmidazolium, our method also identified potentially novel agents for targeting HCC. We experimentally verified that one of these novel agents, prenylamine, induced HCC cell apoptosis using 3-(4,5-dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide, an acridine orange/ethidium bromide stain, and electron microscopy. In addition, we found that prenylamine not only affected several classic apoptosis-related proteins, including Bax, Bcl-2, and cytochrome c, but also increased caspase-3 activity. These candidate small molecular drugs

  4. Two statistics for evaluating parameter identifiability and error reduction (United States)

    Doherty, John; Hunt, Randall J.


    Two statistics are presented that can be used to rank input parameters utilized by a model in terms of their relative identifiability based on a given or possible future calibration dataset. Identifiability is defined here as the capability of model calibration to constrain parameters used by a model. Both statistics require that the sensitivity of each model parameter be calculated for each model output for which there are actual or presumed field measurements. Singular value decomposition (SVD) of the weighted sensitivity matrix is then undertaken to quantify the relation between the parameters and observations that, in turn, allows selection of calibration solution and null spaces spanned by unit orthogonal vectors. The first statistic presented, "parameter identifiability", is quantitatively defined as the direction cosine between a parameter and its projection onto the calibration solution space. This varies between zero and one, with zero indicating complete non-identifiability and one indicating complete identifiability. The second statistic, "relative error reduction", indicates the extent to which the calibration process reduces error in estimation of a parameter from its pre-calibration level where its value must be assigned purely on the basis of prior expert knowledge. This is more sophisticated than identifiability, in that it takes greater account of the noise associated with the calibration dataset. Like identifiability, it has a maximum value of one (which can only be achieved if there is no measurement noise). Conceptually it can fall to zero; and even below zero if a calibration problem is poorly posed. An example, based on a coupled groundwater/surface-water model, is included that demonstrates the utility of the statistics. ?? 2009 Elsevier B.V.

  5. Tracing Scientific Facilities through the Research Literature Using Persistent Identifiers (United States)

    Mayernik, M. S.; Maull, K. E.


    Tracing persistent identifiers to their source publications is an easy task when authors use them, since it is a simple matter of matching the persistent identifier to the specific text string of the identifier. However, trying to understand if a publication uses the resource behind an identifier when such identifier is not referenced explicitly is a harder task. In this research, we explore the effectiveness of alternative strategies of associating publications with uses of the resource referenced by an identifier when it may not be explicit. This project is explored within the context of the NCAR supercomputer, where we are broadly interesting in the science that can be traced to the usage of the NCAR supercomputing facility, by way of the peer-reviewed research publications that utilize and reference it. In this project we explore several ways of drawing linkages between publications and the NCAR supercomputing resources. Identifying and compiling peer-reviewed publications related to NCAR supercomputer usage are explored via three sources: 1) User-supplied publications gathered through a community survey, 2) publications that were identified via manual searching of the Google scholar search index, and 3) publications associated with National Science Foundation (NSF) grants extracted from a public NSF database. These three sources represent three styles of collecting information about publications that likely imply usage of the NCAR supercomputing facilities. Each source has strengths and weaknesses, thus our discussion will explore how our publication identification and analysis methods vary in terms of accuracy, reliability, and effort. We will also discuss strategies for enabling more efficient tracing of research impacts of supercomputing facilities going forward through the assignment of a persistent web identifier to the NCAR supercomputer. While this solution has potential to greatly enhance our ability to trace the use of the facility through

  6. Structural identifiability analysis of a cardiovascular system model. (United States)

    Pironet, Antoine; Dauby, Pierre C; Chase, J Geoffrey; Docherty, Paul D; Revie, James A; Desaive, Thomas


    The six-chamber cardiovascular system model of Burkhoff and Tyberg has been used in several theoretical and experimental studies. However, this cardiovascular system model (and others derived from it) are not identifiable from any output set. In this work, two such cases of structural non-identifiability are first presented. These cases occur when the model output set only contains a single type of information (pressure or volume). A specific output set is thus chosen, mixing pressure and volume information and containing only a limited number of clinically available measurements. Then, by manipulating the model equations involving these outputs, it is demonstrated that the six-chamber cardiovascular system model is structurally globally identifiable. A further simplification is made, assuming known cardiac valve resistances. Because of the poor practical identifiability of these four parameters, this assumption is usual. Under this hypothesis, the six-chamber cardiovascular system model is structurally identifiable from an even smaller dataset. As a consequence, parameter values computed from limited but well-chosen datasets are theoretically unique. This means that the parameter identification procedure can safely be performed on the model from such a well-chosen dataset. Thus, the model may be considered suitable for use in diagnosis. Copyright © 2016 IPEM. Published by Elsevier Ltd. All rights reserved.

  7. Laboratory evaluation of the IriScan prototype biometric identifier

    Energy Technology Data Exchange (ETDEWEB)

    Bouchier, F.; Ahrens, J.S.; Wells, G.


    One thing that all access control applications have in common is the need to identify those individuals authorized to gain access to an area. Traditionally, the identification is based on something that person possesses, such as a key or badge, or something they know, such as a PIN or password. Biometric identifiers make their decisions based on the physiological or behavioral characteristics of individuals. The potential of biometrics devices to positively identify individuals has made them attractive for use in access control and computer security applications. However, no systems perform perfectly, so it is important to understand what a biometric device`s performance is under real world conditions before deciding to implement one in an access control system. This paper will describe the evaluation of a prototype biometric identifier provided by IriScan Incorporated. This identifier was developed to recognize individual human beings based on the distinctive visual characteristics of the irises of their eyes. The main goal of the evaluation was to determine whether the system has potential as an access control device within the Department of Energy (DOE). The primary interest was an estimate of the accuracy of the system in terms of false accept and false reject rates. Data was also collected to estimate throughput time and user acceptability. The performance of the system during the test will be discussed. Lessons learned during the test which may aid in further testing and simplify implementation of a production system will also be discussed.

  8. ENU Mutagenesis in Mice Identifies Candidate Genes For Hypogonadism (United States)

    Weiss, Jeffrey; Hurley, Lisa A.; Harris, Rebecca M.; Finlayson, Courtney; Tong, Minghan; Fisher, Lisa A.; Moran, Jennifer L.; Beier, David R.; Mason, Christopher; Jameson, J. Larry


    Genome-wide mutagenesis was performed in mice to identify candidate genes for male infertility, for which the predominant causes remain idiopathic. Mice were mutagenized using N-ethyl-N-nitrosourea (ENU), bred, and screened for phenotypes associated with the male urogenital system. Fifteen heritable lines were isolated and chromosomal loci were assigned using low density genome-wide SNP arrays. Ten of the fifteen lines were pursued further using higher resolution SNP analysis to narrow the candidate gene regions. Exon sequencing of candidate genes identified mutations in mice with cystic kidneys (Bicc1), cryptorchidism (Rxfp2), restricted germ cell deficiency (Plk4), and severe germ cell deficiency (Prdm9). In two other lines with severe hypogonadism candidate sequencing failed to identify mutations, suggesting defects in genes with previously undocumented roles in gonadal function. These genomic intervals were sequenced in their entirety and a candidate mutation was identified in SnrpE in one of the two lines. The line harboring the SnrpE variant retains substantial spermatogenesis despite small testis size, an unusual phenotype. In addition to the reproductive defects, heritable phenotypes were observed in mice with ataxia (Myo5a), tremors (Pmp22), growth retardation (unknown gene), and hydrocephalus (unknown gene). These results demonstrate that the ENU screen is an effective tool for identifying potential causes of male infertility. PMID:22258617

  9. SitesIdentify: a protein functional site prediction tool

    Directory of Open Access Journals (Sweden)

    Doig Andrew J


    Full Text Available Abstract Background The rate of protein structures being deposited in the Protein Data Bank surpasses the capacity to experimentally characterise them and therefore computational methods to analyse these structures have become increasingly important. Identifying the region of the protein most likely to be involved in function is useful in order to gain information about its potential role. There are many available approaches to predict functional site, but many are not made available via a publicly-accessible application. Results Here we present a functional site prediction tool (SitesIdentify, based on combining sequence conservation information with geometry-based cleft identification, that is freely available via a web-server. We have shown that SitesIdentify compares favourably to other functional site prediction tools in a comparison of seven methods on a non-redundant set of 237 enzymes with annotated active sites. Conclusion SitesIdentify is able to produce comparable accuracy in predicting functional sites to its closest available counterpart, but in addition achieves improved accuracy for proteins with few characterised homologues. SitesIdentify is available via a webserver at

  10. Fungi identify the geographic origin of dust samples. (United States)

    Grantham, Neal S; Reich, Brian J; Pacifici, Krishna; Laber, Eric B; Menninger, Holly L; Henley, Jessica B; Barberán, Albert; Leff, Jonathan W; Fierer, Noah; Dunn, Robert R


    There is a long history of archaeologists and forensic scientists using pollen found in a dust sample to identify its geographic origin or history. Such palynological approaches have important limitations as they require time-consuming identification of pollen grains, a priori knowledge of plant species distributions, and a sufficient diversity of pollen types to permit spatial or temporal identification. We demonstrate an alternative approach based on DNA sequencing analyses of the fungal diversity found in dust samples. Using nearly 1,000 dust samples collected from across the continental U.S., our analyses identify up to 40,000 fungal taxa from these samples, many of which exhibit a high degree of geographic endemism. We develop a statistical learning algorithm via discriminant analysis that exploits this geographic endemicity in the fungal diversity to correctly identify samples to within a few hundred kilometers of their geographic origin with high probability. In addition, our statistical approach provides a measure of certainty for each prediction, in contrast with current palynology methods that are almost always based on expert opinion and devoid of statistical inference. Fungal taxa found in dust samples can therefore be used to identify the origin of that dust and, more importantly, we can quantify our degree of certainty that a sample originated in a particular place. This work opens up a new approach to forensic biology that could be used by scientists to identify the origin of dust or soil samples found on objects, clothing, or archaeological artifacts.

  11. Identifying risk event in Indonesian fresh meat supply chain (United States)

    Wahyuni, H. C.; Vanany, I.; Ciptomulyono, U.


    The aim of this paper is to identify risk issues in Indonesian fresh meat supply chain from the farm until to the “plate”. The critical points for food safety in physical fresh meat product flow are also identified. The paper employed one case study in the Indonesian fresh meat company by conducting observations and in-depth three stages of interviews. At the first interview, the players, process, and activities in the fresh meat industry were identified. In the second interview, critical points for food safety were recognized. The risk events in each player and process were identified in the last interview. The research will be conducted in three stages, but this article focuses on risk identification process (first stage) only. The second stage is measuring risk and the third stage focuses on determining the value of risk priority. The results showed that there were four players in the fresh meat supply chain: livestock (source), slaughter (make), distributor and retail (deliver). Each player has different activities and identified 16 risk events in the fresh meat supply chain. Some of the strategies that can be used to reduce the occurrence of such risks include improving the ability of laborers on food safety systems, improving cutting equipment and distribution processes

  12. Fungi identify the geographic origin of dust samples.

    Directory of Open Access Journals (Sweden)

    Neal S Grantham

    Full Text Available There is a long history of archaeologists and forensic scientists using pollen found in a dust sample to identify its geographic origin or history. Such palynological approaches have important limitations as they require time-consuming identification of pollen grains, a priori knowledge of plant species distributions, and a sufficient diversity of pollen types to permit spatial or temporal identification. We demonstrate an alternative approach based on DNA sequencing analyses of the fungal diversity found in dust samples. Using nearly 1,000 dust samples collected from across the continental U.S., our analyses identify up to 40,000 fungal taxa from these samples, many of which exhibit a high degree of geographic endemism. We develop a statistical learning algorithm via discriminant analysis that exploits this geographic endemicity in the fungal diversity to correctly identify samples to within a few hundred kilometers of their geographic origin with high probability. In addition, our statistical approach provides a measure of certainty for each prediction, in contrast with current palynology methods that are almost always based on expert opinion and devoid of statistical inference. Fungal taxa found in dust samples can therefore be used to identify the origin of that dust and, more importantly, we can quantify our degree of certainty that a sample originated in a particular place. This work opens up a new approach to forensic biology that could be used by scientists to identify the origin of dust or soil samples found on objects, clothing, or archaeological artifacts.

  13. Family and academic performance: identifying high school student profiles

    Directory of Open Access Journals (Sweden)

    Alicia Aleli Chaparro Caso López


    Full Text Available The objective of this study was to identify profiles of high school students, based on variables related to academic performance, socioeconomic status, cultural capital and family organization. A total of 21,724 high school students, from the five municipalities of the state of Baja California, took part. A K-means cluster analysis was performed to identify the profiles. The analyses identified two clearly-defined clusters: Cluster 1 grouped together students with high academic performance and who achieved higher scores for socioeconomic status, cultural capital and family involvement, whereas Cluster 2 brought together students with low academic achievement, and who also obtained lower scores for socioeconomic status and cultural capital, and had less family involvement. It is concluded that the family variables analyzed form student profiles that can be related to academic achievement.

  14. Benchmarking in Identifying Priority Directions of Development of Telecommunication Operators

    Directory of Open Access Journals (Sweden)

    Zaharchenko Lolita A.


    Full Text Available The article analyses evolution of development and possibilities of application of benchmarking in the telecommunication sphere. It studies essence of benchmarking on the basis of generalisation of approaches of different scientists to definition of this notion. In order to improve activity of telecommunication operators, the article identifies the benchmarking technology and main factors, that determine success of the operator in the modern market economy, and the mechanism of benchmarking and component stages of carrying out benchmarking by a telecommunication operator. It analyses the telecommunication market and identifies dynamics of its development and tendencies of change of the composition of telecommunication operators and providers. Having generalised the existing experience of benchmarking application, the article identifies main types of benchmarking of telecommunication operators by the following features: by the level of conduct of (branch, inter-branch and international benchmarking; by relation to participation in the conduct (competitive and joint; and with respect to the enterprise environment (internal and external.

  15. Drosophila Cancer Models Identify Functional Differences between Ret Fusions

    Directory of Open Access Journals (Sweden)

    Sarah Levinson


    Full Text Available We generated and compared Drosophila models of RET fusions CCDC6-RET and NCOA4-RET. Both RET fusions directed cells to migrate, delaminate, and undergo EMT, and both resulted in lethality when broadly expressed. In all phenotypes examined, NCOA4-RET was more severe than CCDC6-RET, mirroring their effects on patients. A functional screen against the Drosophila kinome and a library of cancer drugs found that CCDC6-RET and NCOA4-RET acted through different signaling networks and displayed distinct drug sensitivities. Combining data from the kinome and drug screens identified the WEE1 inhibitor AZD1775 plus the multi-kinase inhibitor sorafenib as a synergistic drug combination that is specific for NCOA4-RET. Our work emphasizes the importance of identifying and tailoring a patient’s treatment to their specific RET fusion isoform and identifies a multi-targeted therapy that may prove effective against tumors containing the NCOA4-RET fusion.

  16. Identifying the Persons in Charge of an Organizational Change Process

    Directory of Open Access Journals (Sweden)

    Daniela BRĂDUŢANU


    Full Text Available The purpose of this research is to identify if there is a correlation between the change agent and resistance in order to change and to identify the persons who are in charge of conducting a change process within the Romanian organizations. To answer these two questions we have researched the current literature and carried out a research in the field, and discovered that even if in many cases the change agent can represent a force generating resistance to change within an organization, it does not apply to the analyzed sample. Also, we have identified the main categories of people who are in charge of implementing a new change and the results differ, depending on the size of the organization. This information is valuable for managers, researchers and practitioners.

  17. Understanding the nurse's role in identifying children with intellectual disability. (United States)

    Delahunty, Lauren


    The early diagnosis of children who have intellectual disability (ID) is crucial to ensuring the varied and complex needs of these people and their families are met in a timely and appropriate way. The ability to easily identify all children who should be assessed for ID would increase the chances of children with ID being diagnosed early on in life. This article describes ID, the kind of support children with ID need, and how nursing staff might use the Child and Adolescent Intellectual Disability Screening Questionnaire (CAIDS-Q) to help identify children who should be formally assessed for ID. Nurses who would benefit from a greater ability to identify ID include health visitors, school nurses, practice nurses, and nurses working in paediatric clinics.

  18. A Study of Scientometric Methods to Identify Emerging Technologies

    Energy Technology Data Exchange (ETDEWEB)

    Abercrombie, Robert K [ORNL; Udoeyop, Akaninyene W [ORNL


    This work examines a scientometric model that tracks the emergence of an identified technology from initial discovery (via original scientific and conference literature), through critical discoveries (via original scientific, conference literature and patents), transitioning through Technology Readiness Levels (TRLs) and ultimately on to commercial application. During the period of innovation and technology transfer, the impact of scholarly works, patents and on-line web news sources are identified. As trends develop, currency of citations, collaboration indicators, and on-line news patterns are identified. The combinations of four distinct and separate searchable on-line networked sources (i.e., scholarly publications and citation, worldwide patents, news archives, and on-line mapping networks) are assembled to become one collective network (a dataset for analysis of relations). This established network becomes the basis from which to quickly analyze the temporal flow of activity (searchable events) for the example subject domain we investigated.

  19. Proteomic and Genetic Approaches Identify Syk as an AML Target (United States)

    Hahn, Cynthia K.; Berchuck, Jacob E.; Ross, Kenneth N.; Kakoza, Rose M.; Clauser, Karl; Schinzel, Anna C.; Ross, Linda; Galinsky, Ilene; Davis, Tina N.; Silver, Serena J.; Root, David E.; Stone, Richard M.; DeAngelo, Daniel J.; Carroll, Martin; Hahn, William C.; Carr, Steven A.; Golub, Todd R.; Kung, Andrew L.; Stegmaier, Kimberly


    SUMMARY Cell-based screening can facilitate rapid identification of compounds inducing complex cellular phenotypes. Advancing a compound toward the clinic, however, generally requires identification of precise mechanisms of action. We previously found that epidermal growth factor receptor (EGFR) inhibitors induce acute myeloid leukemia (AML) differentiation via a non-EGFR mechanism. In this report, we integrated proteomic and RNAi-based strategies to identify their off-target anti-AML mechanism. These orthogonal approaches identified Syk as a target in AML. Genetic and pharmacological inactivation of Syk with a drug in clinical trial for other indications promoted differentiation of AML cells and attenuated leukemia growth in vivo. These results demonstrate the power of integrating diverse chemical, proteomic, and genomic screening approaches to identify therapeutic strategies for cancer. PMID:19800574

  20. Identifying content for simulation-based curricula in urology

    DEFF Research Database (Denmark)

    Nayahangan, Leizl Joy; Hansen, Rikke Bolling; Lindorff-Larsen, Karen Gilboe


    is performed by an inexperienced physician; and the feasibility of simulation training. Round 3 involved elimination and reranking of procedures according to priority. Results: The response rates for the three Delphi rounds were 70%, 55% and 67%, respectively. The 34 procedures identified in Round 1 were......Objective: Simulation-based training is well recognized in the transforming field of urological surgery; however, integration into the curriculum is often unstructured. Development of simulation-based curricula should follow a stepwise approach starting with a needs assessment. This study aimed...... to identify technical procedures in urology that should be included in a simulation-based curriculum for residency training. Materials and methods: A national needs assessment was performed using the Delphi method involving 56 experts with significant roles in the education of urologists. Round 1 identified...

  1. Identifying Method of Drunk Driving Based on Driving Behavior

    Directory of Open Access Journals (Sweden)

    Xiaohua Zhao


    Full Text Available Drunk driving is one of the leading causes contributing to traffic crashes. There are numerous issues that need to be resolved with the current method of identifying drunk driving. Driving behavior, with the characteristic of real-time, was extensively researched to identify impaired driving behaviors. In this paper, the drives with BACs above 0.05% were defined as drunk driving state. A detailed comparison was made between normal driving and drunk driving. The experiment in driving simulator was designed to collect the driving performance data of the groups. According to the characteristics analysis for the effect of alcohol on driving performance, seven significant indicators were extracted and the drunk driving was identified by the Fisher Discriminant Method. The discriminant function demonstrated a high accuracy of classification. The optimal critical score to differentiate normal from drinking state was found to be 0. The evaluation result verifies the accuracy of classification method.

  2. Identifying, studying and making good use of macromolecular crystals (United States)

    Calero, Guillermo; Cohen, Aina E.; Luft, Joseph R.; Newman, Janet; Snell, Edward H.


    Structural biology has contributed tremendous knowledge to the understanding of life on the molecular scale. The Protein Data Bank, a depository of this structural knowledge, currently contains over 100 000 protein structures, with the majority stemming from X-ray crystallography. As the name might suggest, crystallography requires crystals. As detectors become more sensitive and X-ray sources more intense, the notion of a crystal is gradually changing from one large enough to embellish expensive jewellery to objects that have external dimensions of the order of the wavelength of visible light. Identifying these crystals is a prerequisite to their study. This paper discusses developments in identifying these crystals during crystallization screening and distinguishing them from other potential outcomes. The practical aspects of ensuring that once a crystal is identified it can then be positioned in the X-ray beam for data collection are also addressed. PMID:25084371

  3. Identifying suicidal behavior among adolescents using administrative claims data. (United States)

    Callahan, S Todd; Fuchs, D Catherine; Shelton, Richard C; Balmer, Leanne S; Dudley, Judith A; Gideon, Patricia S; Deranieri, Michelle M; Stratton, Shannon M; Williams, Candice L; Ray, Wayne A; Cooper, William O


    To assess the safety of psychotropic medication use in children and adolescents, it is critical to be able to identify suicidal behaviors from medical claims data and distinguish them from other injuries. The purpose of this study was to develop an algorithm using administrative claims data to identify medically treated suicidal behavior in a cohort of children and adolescents. The cohort included 80,183 youth (6-18 years) enrolled in Tennessee's Medicaid program from 1995-2006 who were prescribed antidepressants. Potential episodes of suicidal behavior were identified using external cause-of-injury codes (E-codes) and ICD-9-CM codes corresponding to the potential mechanisms of or injuries resulting from suicidal behavior. For each identified episode, medical records were reviewed to determine if the injury was self-inflicted and if intent to die was explicitly stated or could be inferred. Medical records were reviewed for 2676 episodes of potential self-harm identified through claims data. Among 1162 episodes that were classified as suicidal behavior, 1117 (96%) had a claim for suicide and self-inflicted injury, poisoning by drugs, or both. The positive predictive value of code groups to predict suicidal behavior ranged from 0-88% and improved when there was a concomitant hospitalization but with the limitation of excluding some episodes of confirmed suicidal behavior. Nearly all episodes of confirmed suicidal behavior in this cohort of youth included an ICD-9-CM code for suicide or poisoning by drugs. An algorithm combining these ICD-9-CM codes and hospital stay greatly improved the positive predictive value for identifying medically treated suicidal behavior. Copyright © 2013 John Wiley & Sons, Ltd.

  4. Feline polycystic kidney disease mutation identified in PKD1. (United States)

    Lyons, Leslie A; Biller, David S; Erdman, Carolyn A; Lipinski, Monika J; Young, Amy E; Roe, Bruce A; Qin, Baifang; Grahn, Robert A


    Autosomal dominant polycystic kidney disease (ADPKD) is a commonly inherited disorder in humans that causes the formation of fluid-filled renal cysts, often leading to renal failure. PKD1 mutations cause 85% of ADPKD. Feline PKD is autosomal dominant and has clinical presentations similar to humans. PKD affects approximately 38% of Persian cats worldwide, which is approximately 6% of cats, making it the most prominent inherited feline disease. Previous analyses have shown significant linkage between the PKD phenotype and microsatellite markers linked to the feline homolog for PKD1. In this report, the feline PKD1 gene was scanned for causative mutations and a C>A transversion was identified at c.10063 (human ref NM_000296) in exon 29, resulting in a stop mutation at position 3284, which suggests a loss of approximately 25% of the C-terminus of the protein. The same mutation has not been identified in humans, although similar regions of the protein are truncated. The C>A transversion has been identified in the heterozygous state in 48 affected cats examined, including 41 Persians, a Siamese, and several other breeds that have been known to outcross with Persians. In addition, the mutation is segregating concordantly in all available PKD families. No unaffected cats have been identified with the mutation. No homozygous cats have been identified, supporting the suggestion that the mutation is embryonic lethal. These data suggest that the stop mutation causes feline PKD, providing a test to identify cats that will develop PKD and demonstrating that the domestic cat is an ideal model for human PKD.

  5. A Framework for Identifying and Understanding Enterprise Systems Benefits

    DEFF Research Database (Denmark)

    Schubert, Petra; Williams, Susan P.


    Purpose – Identifying the benefits arising from implementations of enterprise systems and realizing business value remains a significant challenge for both research and industry. This paper aims to consolidate previous work. It presents a framework for investigating enterprise systems benefits...... and business change, which addresses the identified limitations of previous research and provides a more detailed analysis of benefits and their contextual variation. Design/methodology/approach – Drawing on data gathered from 31 real-world organizations (case studies) of differing size, maturity, and industry...

  6. Clinical staff nurse leadership: Identifying gaps in competency development. (United States)

    Franks-Meeks, Sherron


    To date, there has been no development of a complete, applicable inventory of clinical staff nurse (CSN) leadership role competencies through a valid and reliable methodology. Further, the CSN has not been invited to engage in the identification, definition, or development of their own leadership competencies. Compare existing leadership competencies to identify and highlight gaps in clinical staff nurse leadership role competency development and validation. Literature review. The CSN has not participated in the development of CSN leadership role competencies, nor have the currently identified CSN leadership role competencies been scientifically validated through research. Finally, CSN leadership role competencies are incomplete and do not reflect the CSN perspective. © 2017 Wiley Periodicals, Inc.

  7. PlateRunner: A Search Engine to Identify EMR Boilerplates. (United States)

    Divita, Guy; Workman, T Elizabeth; Carter, Marjorie E; Redd, Andrew; Samore, Matthew H; Gundlapalli, Adi V


    Medical text contains boilerplated content, an artifact of pull-down forms from EMRs. Boilerplated content is the source of challenges for concept extraction on clinical text. This paper introduces PlateRunner, a search engine on boilerplates from the US Department of Veterans Affairs (VA) EMR. Boilerplates containing concepts should be identified and reviewed to recognize challenging formats, identify high yield document titles, and fine tune section zoning. This search engine has the capability to filter negated and asserted concepts, save and search query results. This tool can save queries, search results, and documents found for later analysis.

  8. Identifying Communicational Errors: Organizing Health Care with E-texts

    DEFF Research Database (Denmark)

    Wentzer, Helle


    locations in time and space through semiotic texts is presented, and subsequently applied as a method of analyzing and evaluating the communicative effect of an electronic care record in home care in Denmark. Paradoxes of communication are identified and discussed in relation to the practice...... and organizational development with the electronic record. Identifying errors of communicating through IT providesa crucial opportunity for the organization to reflect on its own working conditions and to educate clinicians to become co-authors and co-designers of ICT-devices....

  9. Radiological difficulty in identifying unicompartmental knee replacement dislocation

    Directory of Open Access Journals (Sweden)

    Mr Oruaro Adebayo Onibere, MBBS, MRCS


    Full Text Available Unicondylar knee replacement is a relatively common elective orthopedic procedure but is not often seen in the Emergency Department setting. Familiarity with normal clinical and radiological appearances is difficult to gain. Dislocation of the mobile bearing component “spacer” is a known complication of unicondylar knee replacements, and these patients will initially present to the accident and Emergency Department. In this setting, an accurate and prompt diagnosis is necessary to appropriately manage the patient's condition. There is normally a radiological challenge in identifying dislocated mobile bearings on plain radiographs. These patients may need to have further imaging, such as a computer tomographic scan to identify the dislocated mobile bearing.

  10. Brain imaging analysis can identify participants under regular mental training. (United States)

    Sato, João R; Kozasa, Elisa H; Russell, Tamara A; Radvany, João; Mello, Luiz E A M; Lacerda, Shirley S; Amaro, Edson


    Multivariate pattern recognition approaches have become a prominent tool in neuroimaging data analysis. These methods enable the classification of groups of participants (e.g. controls and patients) on the basis of subtly different patterns across the whole brain. This study demonstrates that these methods can be used, in combination with automated morphometric analysis of structural MRI, to determine with great accuracy whether a single subject has been engaged in regular mental training or not. The proposed approach allowed us to identify with 94.87% accuracy (pimaging applications, in which participants could be identified based on their mental experience.

  11. Applications for unique identifiers in the geological sciences (United States)

    Klump, J.; Lehnert, K. A.


    Even though geology has always been a generalist discipline in many parts, approaches towards questions about Earth's past have become increasingly interdisciplinary. At the same time, a wealth of samples has been collected, the resulting data have been stored in in disciplinary databases, the interpretations published in scientific literature. In the past these resources have existed alongside each other, semantically linked only by the knowledge of the researcher and his peers. One of the main drivers towards the inception of the world wide web was the ability to link scientific sources over the internet. The Uniform Resource Locator (URL) used to locate resources on the web soon turned out to be ephemeral in nature. A more reliable way of addressing objects was needed, a way of persistent identification to make digital objects, or digital representations of objects, part of the record of science. With their high degree of centralisation the scientific publishing houses were quick to implement and adopt a system for unique and persistent identification, the Digital Object Identifier (DOI) ®. At the same time other identifier systems exist alongside DOI, e.g. URN, ARK, handle ®, and others. There many uses for persistent identification in science, other than the identification of journal articles. DOI are already used for the identification of data, thus making data citable. There are several initiatives to assign identifiers to authors and institutions to allow unique identification. A recent development is the application of persistent identifiers for geological samples. As most data in the geosciences are derived from samples, it is crucial to be able to uniquely identify the samples from which a set of data were derived. Incomplete documentation of samples in publications, use of ambiguous sample names are major obstacles for synthesis studies and re-use of data. Access to samples for re-analysis and re-appraisal is limited due to the lack of a central

  12. Could cognitive vulnerability identify high-risk subjects for schizophrenia? (United States)

    Sarfati, Yves; Hardy-Baylé, Marie-Christine


    This review puts into questions the possible role of cognitive vulnerability markers in prediction and prevention of schizophrenia. Until recently, none of the identified cognitive anomalies has been proved to be definitive. However, as new promising candidates are emerging (DS-CPT, CPT-IP, P suppression, Saccadic Eye Movements), the predictive value of these trait-type anomalies may be criticized regarding four issues, which are discussed: technical, metrological, theoretical, and clinical. As things stand, the existence of a cognitive vulnerability marker, which testify to a permanent pathological trait, does not constitute a sufficient factor to identify and treat subjects who are at risk for schizophrenia. Copyright 2002 Wiley-Liss, Inc.

  13. The Patent Literature As A Shortcut To Identify Knowledge Suppliers

    DEFF Research Database (Denmark)

    Søberg, Peder Veng

    The present paper explores characteristics of valuable patents that have been subject to litigation which resulted in some of the largest fines to patent infringers reported in history. The valuable patents are compared with less valuable patents in order to identify new methods of evaluating...... patents which decreases the time span between a patent is filed and its value can be evaluated when searching the patent literature. A potential benefit thereof could be that the patent literature could become relevant in order to identify potential knowledge suppliers....

  14. An automatic and effective approach in identifying tower cranes (United States)

    Yu, Bo; Niu, Zheng; Wang, Li; Liu, Yaqi


    A method which can distinguish tower cranes from other objects in an image is proposed in this paper. It synthesizes the advantages of both morphological theory and geometrical characters to identify tower cranes accurately. The algorithm uses morphological theory to remove noise and segment images. Moreover, geometrical characters are adopted to extract tower cranes with thresholds. To test the algorithm's practical applicability, we apply it to another image to check the result. The experiments show that the approach can locate the position of tower cranes precisely and calculate the number of cranes at 100% accuracy rate. It can be applied to identifying tower cranes in small regions.

  15. Use of UV absorption for identifying subspecies of Artemisia tridentata

    International Nuclear Information System (INIS)

    Spomer, G.G.; Henderson, D.M.


    Use of UV absorption spectra for identifying subspecies of Artemisia tridentata Nutt. was investigated by analyzing the relative optical densities of alcohol extracts from herbarium and fresh plant material at 240 nm, 250 nm, and 265 nm. In all but 1 comparison, mean relative optical densities were significantly different (p=0.95) between subspecies, but intraplant and intrasubspecies variation and overlap was found to be too large to permit use of UV absorbance alone for identifying individual specimens. These results held whether dry or fresh leaves were extracted, or whether methanol or ethanol was used as the extracting solvent. (author)

  16. Identifying different learning styles to enhance the learning experience. (United States)

    Anderson, Irene


    Identifying your preferred learning style can be a useful way to optimise learning opportunities, and can help learners to recognise their strengths and areas for development in the way that learning takes place. It can also help teachers (educators) to recognise where additional activities are required to ensure the learning experience is robust and effective. There are several models available that may be used to identify learning styles. This article discusses these models and considers their usefulness in healthcare education. Models of teaching styles are also considered.

  17. Modelling intelligence-led policing to identify its potential

    NARCIS (Netherlands)

    Hengst-Bruggeling, M. den; Graaf, H.A.L.M. de; Scheepstal, P.G.M. van


    lntelligence-led policing is a concept of policing that has been applied throughout the world. Despite some encouraging reports, the effect of intelligence-led policing is largely unknown. This paper presents a method with which it is possible to identify intelligence-led policing's potential to

  18. Use of Photogrammetry and Biomechanical Gait analysis to Identify Individuals

    DEFF Research Database (Denmark)

    Larsen, Peter Kastmand; Simonsen, Erik Bruun; Lynnerup, Niels

    Photogrammetry and recognition of gait patterns are valuable tools to help identify perpetrators based on surveillance recordings. We have found that stature but only few other measures have a satisfying reproducibility for use in forensics. Several gait variables with high recognition rates were...



    Kumar; Kumar; Shaleen; Wasif; Amit


    We report the case of a 53 year old lady who underwent laparoscopic cholecystectomy and was found to have an accessory cystic duct close to the fundus. Careful dissection of the liver bed was done and the duct clipped preventing a bile leak. The presence of such ducts though rare should be identified during surgery to prevent potential complications.

  20. 40 CFR 255.10 - Criteria for identifying regions. (United States)


    ... the State plan. (2) Boundary selection which would require the creation of new agencies should be... institutional gaps or inadequacies are found, regions should be identified keeping in mind which agencies would... of geologic and hydrologic conditions, such as soil suitability, land availability, natural barriers...

  1. Identifying and responding to barriers impacting women educators ...

    African Journals Online (AJOL)

    Drawing on these reflections, this article explores the notion of academic citizenship as it relates to the status and practice of these five educators who teach at various institutions of higher education in Southern Africa. The article is divided into two parts. a) Part 1 identifies the barriers impacting the participants. It draws on ...

  2. Identifying Quality in Preschool Education: Progress and Challenge (United States)

    Hughes, Jan N.


    In this article, the author comments on Dominguez, Vitiello, Maier, and Greenfield's (2010) article on identifying quality in preschool education. Dominguez et al. have conducted a methodologically sophisticated study describing the growth of learning behavior among Head Start children. By doing so, they contribute to a growing body of evidence…

  3. Identifying and Treating Race-Based Trauma in Counseling (United States)

    Hemmings, Carrie; Evans, Amanda M.


    This study investigated 106 counseling professionals' experiences with identifying and treating race-based trauma and the relationship between training and treatment. Competency was assessed with the Race-Based Trauma Survey for Counselors. Although most participants reported working with clients who had symptoms associated with race-based trauma,…

  4. Identifying strategies to improve research publication output in ...

    African Journals Online (AJOL)

    The health research community in South Africa annually produces a fair number of research papers in national and international health and related journals. Unfortunately, the proportion of papers produced by authors in health and rehabilitation sciences is insignificant compared with other disciplines. To identify strategies ...

  5. Identifying values and beliefs in an outcomes-based curriculum ...

    African Journals Online (AJOL)

    There is therefore a need for teachers to be sensitised to the different values embedded in each belief system and all cultureal orientations. The prevalence of values and belief systems in the OBE curricula of C2005 and the NCS will have to be acknowledged, identified, and promoted. South African Journal of Education ...

  6. Identifying values and beliefs in an outcomes-based curriculum

    African Journals Online (AJOL)

    Erna Kinsey

    fore a need for teachers to be sensitised to the different values embedded in each belief system and all cultureal orientations. The prevalence of values and belief systems in the OBE curricula of C2005 and the NCS will have to be acknowledged, identified, and promoted. Introduction. Value, religious and belief contents ...

  7. Whole-Exome Sequencing Identifies Novel Variants for Tooth Agenesis. (United States)

    Dinckan, N; Du, R; Petty, L E; Coban-Akdemir, Z; Jhangiani, S N; Paine, I; Baugh, E H; Erdem, A P; Kayserili, H; Doddapaneni, H; Hu, J; Muzny, D M; Boerwinkle, E; Gibbs, R A; Lupski, J R; Uyguner, Z O; Below, J E; Letra, A


    Tooth agenesis is a common craniofacial abnormality in humans and represents failure to develop 1 or more permanent teeth. Tooth agenesis is complex, and variations in about a dozen genes have been reported as contributing to the etiology. Here, we combined whole-exome sequencing, array-based genotyping, and linkage analysis to identify putative pathogenic variants in candidate disease genes for tooth agenesis in 10 multiplex Turkish families. Novel homozygous and heterozygous variants in LRP6, DKK1, LAMA3, and COL17A1 genes, as well as known variants in WNT10A, were identified as likely pathogenic in isolated tooth agenesis. Novel variants in KREMEN1 were identified as likely pathogenic in 2 families with suspected syndromic tooth agenesis. Variants in more than 1 gene were identified segregating with tooth agenesis in 2 families, suggesting oligogenic inheritance. Structural modeling of missense variants suggests deleterious effects to the encoded proteins. Functional analysis of an indel variant (c.3607+3_6del) in LRP6 suggested that the predicted resulting mRNA is subject to nonsense-mediated decay. Our results support a major role for WNT pathways genes in the etiology of tooth agenesis while revealing new candidate genes. Moreover, oligogenic cosegregation was suggestive for complex inheritance and potentially complex gene product interactions during development, contributing to improved understanding of the genetic etiology of familial tooth agenesis.

  8. Severe hypodontia: identifying patterns of human tooth agenesis

    NARCIS (Netherlands)

    Tan, S.P.K.; van Wijk, A.J.; Prahl-Andersen, B.


    Tooth agenesis is the most common dental anomaly. The aim of this retrospective study was to identify common patterns of tooth agenesis in a sample of 92 patients (55 females and 37 males; mean age 27.7 years) with non-syndromic severe hypodontia. The Tooth Agenesis Code (TAC) procedure was used for

  9. Opportunistic Beacon Networks: Information Dissemination via Wireless Network Identifiers

    NARCIS (Netherlands)

    Türkes, Okan; Scholten, Johan; Havinga, Paul J.M.


    This paper presents OBN, a universal opportunistic ad hoc networking model particularly intended for smart mobile devices. It enables fast and lightweight data dissemination in wireless community networks through the utilization of universally-available wireless network identifiers. As a ubiquitous

  10. Human group C rotaviruses identified in Kenya | Mwenda | East ...

    African Journals Online (AJOL)

    Subjects and Methods:Faecal samples were collected from 119 infants and young children with diarrhoea and were analysed by commercial ELISA and polyacrylamide gel electrophoresis (SDS-PAGE) to identify possible non-group A rotaviruses. Extraction of any potential rrotavirus double-stranded RNA from faeces amd ...

  11. X-factor for innovation: identifying future excellent professionals

    NARCIS (Netherlands)

    den Hertog, J.H.


    In this study we wanted to identify which type of individual is capable of achieving professional excellence. Our main question therefore read: which individual antecedents predict professional excellence? We chose to focus on personality traits and specifically on proactive personality - the

  12. Identifying strategies to improve the effectiveness of booster seat laws (United States)


    The objective of this project was to identify strategies to improve the effectiveness of booster seat laws. The project explored the possible factors that relate to the use and nonuse of booster seats, and examined the attitudes of law enforcement of...


    African Journals Online (AJOL)



    Jul 1, 2017 ... Abstract. This study examines the level of audience awareness of, and determining the effectiveness of the. National Agency for Food and Drug Administration and Control (NAFDAC)'s use of, the. Mobile Authentication Service (MAS) in identifying fake and substandard drugs in Nigeria. The study, anchored ...

  14. Identifying the Transgender Population in the Medicare Program (United States)

    Proctor, Kimberly; Haffer, Samuel C.; Ewald, Erin; Hodge, Carla; James, Cara V.


    Abstract Purpose: To identify and describe the transgender population in the Medicare program using administrative data. Methods: Using a combination of International Classification of Diseases ninth edition (ICD-9) codes relating to transsexualism and gender identity disorder, we analyzed 100% of the 2013 Centers for Medicare & Medicaid Services (CMS) Medicare Fee-For-Service (FFS) “final action” claims from both institutional and noninstitutional providers (∼1 billion claims) to identify individuals who may be transgender Medicare beneficiaries. To confirm, we developed and applied a multistage validation process. Results: Four thousand ninety-eight transgender beneficiaries were identified, of which ∼90% had confirmatory diagnoses, billing codes, or evidence of a hormone prescription. In general, the racial, ethnic, and geographic distribution of the Medicare transgender population tends to reflect the broader Medicare population. However, age, original entitlement status, and disease burden of the transgender population appear substantially different. Conclusions: Using a variety of claims information, ranging from claims history to additional diagnoses, billing modifiers, and hormone prescriptions, we demonstrate that administrative data provide a valuable resource for identifying a lower bound of the Medicare transgender population. In addition, we provide a baseline description of the diversity and disease burden of the population and a framework for future research. PMID:28861539

  15. Research Note Identifying key grazing indicators to monitor trends in ...

    African Journals Online (AJOL)

    Research Note Identifying key grazing indicators to monitor trends in the veld condition of Lambert's Bay Strandveld, South Africa. ... from which a minimum number of species necessary to monitor trends in the condition of the veld were determined, making it user-friendly for land-users, extension officers and others. The key ...

  16. Prevalent Diseases Identified in Semi-Industrial Poultry Farming in ...

    African Journals Online (AJOL)

    This study was conducted in 2003-2007 with the aim of identifying prevalent diseases in modern poultry farming in Mali. It covered 22 modern layer farms located in the suburban areas of Bamako District and of Sikasso and Segou towns. Analyses focused on a total of 536 samples, 260 sera, 254 eggs, 149 organ samples, ...

  17. Identifying and Evaluating External Validity Evidence for Passing Scores (United States)

    Davis-Becker, Susan L.; Buckendahl, Chad W.


    A critical component of the standard setting process is collecting evidence to evaluate the recommended cut scores and their use for making decisions and classifying students based on test performance. Kane (1994, 2001) proposed a framework by which practitioners can identify and evaluate evidence of the results of the standard setting from (1)…

  18. Identifying Hearing Loss in Young Children: Technology Replaces the Bell (United States)

    Eiserman, William; Shisler, Lenore


    Hearing loss can too easily be misdiagnosed or overlooked by providers serving young children. Parents and professionals may observe a language delay--an "invisible" condition--while failing to identify the underlying cause. Otoacoustic emissions (OAE) hearing screening technology, used extensively with newborns, is becoming an essential tool,…

  19. Does mid upper arm circumference identify all acute malnourished 6 ...

    African Journals Online (AJOL)

    How well MUAC and/or MUACZ scores correlate with states of nutrition defined by WHZ or BAZ is the subject of controversy with different authors presenting different opinions.9–11 Weight- for-height below -3 Standard Deviation (SD) is a highly specific criterion to identify severely acutely malnourished infants and children.

  20. Identifying the best climatic predictors in ecology and evolution

    NARCIS (Netherlands)

    Van de Pol, M.; Bailey, Liam; McLean, Nina; Rijsdijk, Laurie; Lawson, C.R.; Brouwer, L.


    1.Ecologists and many evolutionary biologists relate variation in physiological, behavioral, life-history, demographic, population and community traits to variation in weather, a key environmental driver. However, identifying which weather variables (e.g. rain, temperature, El Niño index), over

  1. Identifying marine pelagic ecosystem management objectives and indicators

    DEFF Research Database (Denmark)

    Trenkel, Verena M.; Hintzen, Niels T.; Farnsworth, Keith D.


    to the development of objectives, for this study stakeholders explored intermediate level ecological, economic and social management objectives for Northeast Atlantic pelagic ecosystems. Stakeholder workshops were undertaken with participants being free to identify objectives based on their own insights and needs...

  2. Performance testing to identify climate-ready trees (United States)

    E.Gregory McPherson; Alison M. Berry; Natalie S. van Doorn


    Urban forests produce ecosystem services that can benefit city dwellers, but are especially vulnerable to climate change stressors such as heat, drought, extreme winds and pests. Tree selection is an important decision point for managers wanting to transition to a more stable and resilient urban forest structure. This study describes a five-step process to identify and...

  3. Identifying the best market to sell: A cost function formulation

    Indian Academy of Sciences (India)

    over-hedging, full-hedging, or under-hedging strategies, depending on whether the two random prices are ... An integrated problem of procuring, processing and trading of commodities is proposed. (Devalkar et al ... We now formulate an optimization approach to enable a farmer to identify the market where we can sell with ...

  4. Using an Online Dictionary for Identifying the Meanings of Verb ...

    African Journals Online (AJOL)


    Abstract: This article reports on the results of a study which investigated the use of an online dictionary by Chinese EFL learners in identifying the meanings of verb phrases. Thirty-two stu- dents with English as major subject participated in a meaning determination task with and without the help of the Macmillan English ...

  5. Identifying Drug–Drug Interactions by Data Mining

    DEFF Research Database (Denmark)

    Hansen, Peter Wæde; Clemmensen, Line Katrine Harder; Sehested, Thomas S.G.


    ) and two had a known interaction in a closely related drug group (oripavine derivatives [buprenorphine] and natural opium alkaloids). Antipropulsives had an unknown signal of increasing INR. Conclusions—We were able to identify known warfarin–drug interactions without a prior hypothesis using clinical...

  6. A Computer-Based Instrument That Identifies Common Science Misconceptions (United States)

    Larrabee, Timothy G.; Stein, Mary; Barman, Charles


    This article describes the rationale for and development of a computer-based instrument that helps identify commonly held science misconceptions. The instrument, known as the Science Beliefs Test, is a 47-item instrument that targets topics in chemistry, physics, biology, earth science, and astronomy. The use of an online data collection system…

  7. Identifying sources and estimating glandular output of salivary TIMP-1

    DEFF Research Database (Denmark)

    Holten-Andersen, L; Beier Jensen, S; Bardow, A


    Objective. Tissue inhibitor of metalloproteinases 1 (TIMP-1) has been identified as a potential biomarker in diseases such as cancer, cardiovascular diseases and diabetes. Since TIMP-1 resides in most tissues and bodily fluids, we evaluated the potential of using saliva to obtain reproducible TIMP...

  8. Identifying core domains to assess flare in rheumatoid arthritis

    DEFF Research Database (Denmark)

    Bartlett, Susan J; Hewlett, Sarah; Bingham, Clifton O


    For rheumatoid arthritis (RA), there is no consensus on how to define and assess flare. Variability in flare definitions impairs understanding of findings across studies and limits ability to pool results. The OMERACT RA Flare Group sought to identify domains to define RA flares from patient...

  9. Identifying Food Safety Concerns when Communication Barriers Exist (United States)

    Neal, Jack A.; Dawson, Mary; Madera, Juan M.


    Abstract: Students must be prepared to lead a diverse workforce. The objective of this study was to establish a teaching method that helps students identify barriers to food safety while working in a simulated environment with communication barriers. This study employed a perspective taking exercise based upon the principles of social learning…

  10. 5 CFR 838.911 - Identifying the retirement system. (United States)


    .... (a) To satisfy the requirements of § 838.804(b)(1), a court order must contain language identifying...) and (b)(2) of this section, language referring to benefits under another retirement system, such as military retired pay, Foreign Service retirement benefits and Central Intelligence Agency retirement...

  11. 5 CFR 838.611 - Identifying the retirement system. (United States)


    ... order must contain language identifying the retirement system to be affected. For example, “CSRS,” “FERS... in paragraphs (b)(1) and (b)(2) of this section, language referring to benefits under another retirement system, such as military retired pay, Foreign Service retirement benefits or Central Intelligence...

  12. Identifying the important factors in simulation models with many factors

    NARCIS (Netherlands)

    Bettonvil, B.; Kleijnen, J.P.C.


    Simulation models may have many parameters and input variables (together called factors), while only a few factors are really important (parsimony principle). For such models this paper presents an effective and efficient screening technique to identify and estimate those important factors. The

  13. Identifying 21st Century STEM Competencies Using Workplace Data (United States)

    Jang, Hyewon


    Gaps between science, technology, engineering, and mathematics (STEM) education and required workplace skills have been identified in industry, academia, and government. Educators acknowledge the need to reform STEM education to better prepare students for their future careers. We pursue this growing interest in the skills needed for STEM…

  14. Gene expression analysis identifies global gene dosage sensitivity in cancer

    DEFF Research Database (Denmark)

    Fehrmann, Rudolf S. N.; Karjalainen, Juha M.; Krajewska, Malgorzata


    Many cancer-associated somatic copy number alterations (SCNAs) are known. Currently, one of the challenges is to identify the molecular downstream effects of these variants. Although several SCNAs are known to change gene expression levels, it is not clear whether each individual SCNA affects gen...

  15. Identifying causal linkages between environmental variables and African conflicts (United States)

    Nguy-Robertson, A. L.; Dartevelle, S.


    Environmental variables that contribute to droughts, flooding, and other natural hazards are often identified as factors contributing to conflict; however, few studies attempt to quantify these causal linkages. Recent research has demonstrated that the environment operates within a dynamical system framework and the influence of variables can be identified from convergent cross mapping (CCM) between shadow manifolds. We propose to use CCM to identify causal linkages between environmental variables and incidences of conflict. This study utilizes time series data from Climate Forecast System ver. 2 and MODIS satellite sensors processed using Google Earth Engine to aggregate country and regional trends. These variables are then compared to Armed Conflict Location & Event Data Project observations at similar scales. Results provide relative rankings of variables and their linkage to conflict. Being able to identify which factors contributed more strongly to a conflict can allow policy makers to prepare solutions to mitigate future crises. Knowledge of the primary environmental factors can lead to the identification of other variables to examine in the causal network influencing conflict.

  16. Identifying and Ranking the Determinants of Tourism Performance

    DEFF Research Database (Denmark)

    Assaf, A.George; Josiassen, Alexander


    and their relative importance. The present study addresses this important gap. We identify and rank the determinants of tourism performance. We also provide performance measures of international tourism destinations. The results are derived using the Data Envelopment Analysis (DEA) and bootstrap truncated regression...

  17. Early post-cleavage stages and abnormalities identified in the ...

    African Journals Online (AJOL)

    Six early, post-cleavage embryonic stages for chokka squid Loligo vulgaris reynaudii eggs that were developed in an aquarium are identified and described, expanding the embryonic stages for this species from 14 to 20. The influence of water temperature on embryonic development is described. At temperatures  ...

  18. Identifying the Determinants of Chronic Absenteeism: A Bioecological Systems Approach (United States)

    Gottfried, Michael A.; Gee, Kevin A.


    Background/Context: Chronic school absenteeism is a pervasive problem across the US; in early education, it is most rampant in kindergarten and its consequences are particularly detrimental, often leading to poorer academic, behavioral and developmental outcomes later in life. Though prior empirical research has identified a broad range of…

  19. Identifying patients at high risk for obstructive sleep apnoea ...

    African Journals Online (AJOL)

    Background: Obstructive sleep apnoea is associated with significant health consequences. A significant proportion of hospitalized patients at risk for obstructive sleep apnoea were never identified and referred for polysomnography for diagnosis. The objective of this study was to determine the factors associated with high ...

  20. Identifying Different Registers of Digital Literacy in Virtual Learning Environments (United States)

    Knutsson, Ola; Blasjo, Mona.; Hallsten, Stina; Karlstrom, Petter


    In this paper social semiotics, and systemic functional linguistics in particular, are used in order to identify registers of digital literacy in the use of virtual learning environments. The framework of social semiotics provides means to systemize and discuss digital literacy as a linguistic and semiotic issue. The following research question…

  1. A method to identify aperiodic disturbances in the ionosphere

    Directory of Open Access Journals (Sweden)

    J.-S. Wang


    Full Text Available In this paper, variations in the ionospheric F2 layer's critical frequency are decomposed into their periodic and aperiodic components. The latter include disturbances caused both by geophysical impacts on the ionosphere and random noise. The spectral whitening method (SWM, a signal-processing technique used in statistical estimation and/or detection, was used to identify aperiodic components in the ionosphere. The whitening algorithm adopted herein is used to divide the Fourier transform of the observed data series by a real envelope function. As a result, periodic components are suppressed and aperiodic components emerge as the dominant contributors. Application to a synthetic data set based on significant simulated periodic features of ionospheric observations containing artificial (and, hence, controllable disturbances was used to validate the SWM for identification of aperiodic components. Although the random noise was somewhat enhanced by post-processing, the artificial disturbances could still be clearly identified. The SWM was then applied to real ionospheric observations. It was found to be more sensitive than the often-used monthly median method to identify geomagnetic effects. In addition, disturbances detected by the SWM were characterized by a Gaussian-type probability density function over all timescales, which further simplifies statistical analysis and suggests that the disturbances thus identified can be compared regardless of timescale.

  2. Identifying Inputs to Leadership Development within an Interdisciplinary Leadership Minor (United States)

    McKim, Aaron J.; Sorensen, Tyson J.; Velez, Jonathan J.


    Researchers conducted a qualitative analysis of students' experiences while enrolled in an interdisciplinary leadership minor with the intent to determine programmatic inputs that spur leadership development. Based on students' reflections, three domains of programmatic inputs for leadership development within the minor were identified. These…

  3. Neurobehavioral Mutants Identified in an ENU Mutagenesis Project

    Energy Technology Data Exchange (ETDEWEB)

    Cook, Melloni N. [University of Memphis; Dunning, Jonathan P [University of Memphis; Wiley, Ronald G [Vanderbilt University and Veterans Administration, Nashville, TN; Chesler, Elissa J [ORNL; Johnson, Dabney K [ORNL; Goldowitz, Daniel [University of Tennessee Health Science Center, Memphis


    We report on a behavioral screening test battery that successfully identified several neurobehavioral mutants among a large-scale ENU-mutagenized mouse population. Large numbers of ENU mutagenized mice were screened for abnormalities in central nervous system function based on abnormal performance in a series of behavior tasks. We developed and employed a high-throughput screen of behavioral tasks to detect behavioral outliers. Twelve mutant pedigrees, representing a broad range of behavioral phenotypes, have been identified. Specifically, we have identified two open field mutants (one displaying hyper-locomotion, the other hypo-locomotion), four tail suspension mutants (all displaying increased immobility), one nociception mutant (displaying abnormal responsiveness to thermal pain), two prepulse inhibition mutants (displaying poor inhibition of the startle response), one anxiety-related mutant (displaying decreased anxiety in the light/dark test), and one learning and memory mutant (displaying reduced response to the conditioned stimulus) These findings highlight the utility of a set of behavioral tasks used in a high throughput screen to identify neurobehavioral mutants. Further analysis (i.e., behavioral and genetic mapping studies) of mutants is in progress with the ultimate goal of identification of novel genes and mouse models relevant to human disorders as well as the identification of novel therapeutic targets.

  4. 7 CFR 70.55 - Check grading officially identified product. (United States)


    ... AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT... 7 Agriculture 3 2010-01-01 2010-01-01 false Check grading officially identified product. 70.55 Section 70.55 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING...

  5. Identifying and Correctly Labeling Sexual Prejudice, Discrimination, and Oppression (United States)

    Dermer, Shannon B.; Smith, Shannon D.; Barto, Korenna K.


    To effectively work with and advocate for lesbians, gay men, and their families, one has to be aware of the individual, relational, and societal forces that may negatively affect them. The focus of this article is to familiarize the reader with terminology used to identify and label sexual prejudice, discrimination, and oppression. The pros and…

  6. A tool for identifying potential Eucalyptus nitens seed orchard sites ...

    African Journals Online (AJOL)

    Shy seed production in orchards of Eucalyptus nitens is a major barrier to the deployment of genetic gain in South African plantations. A machine learning method was used to identify optimal sites for the establishment of E. nitens seed orchards within the plantation forestry landscape of the summer rainfall region of South ...

  7. A Framework for Identifying and Classifying Undergraduate Student Proof Errors (United States)

    Strickland, S.; Rand, B.


    This paper describes a framework for identifying, classifying, and coding student proofs, modified from existing proof-grading rubrics. The framework includes 20 common errors, as well as categories for interpreting the severity of the error. The coding scheme is intended for use in a classroom context, for providing effective student feedback. In…

  8. Researchers Develop Method to Identify Sparticles in Big Bang Conditions

    CERN Multimedia


    Three Northeastern University researchers have proposed a new approach for the highly anticipated discovery of supersymmetric particles, often called sparticles. The methodology, which was published in the December 21 issue of the Physical Review Letters, is based on identifying the hierarchical mass patterns of sparticles, which are assumed to exist in a new class of particle physics theories beyond the Standard Model.

  9. MetaPhinder-Identifying Bacteriophage Sequences in Metagenomic Data Sets

    DEFF Research Database (Denmark)

    Jurtz, Vanessa Isabell; Villarroel, Julia; Lund, Ole


    and understand them. Here we present MetaPhinder, a method to identify assembled genomic fragments (i.e. contigs) of phage origin in metage-nomic data sets. The method is based on a comparison to a database of whole genome bacteriophage sequences, integrating hits to multiple genomes to accomodate for the mosaic...

  10. Easy Long-Term Identifiers and the "Data Paper" (United States)

    Kunze, John


    A new publishing paradigm is needed to cope with the deluge of data artifacts produced by data-intensive science, many of which are vital to data re-use and verification of published scientific conclusions. Due to the limitations of traditional publishing, most of these artifacts are not usually disseminated, cited, or preserved. At the California Digital Library (CDL), one promising approach to the problem is to wrap these artifacts in the metaphor of a "data paper", assigning and managing data citations with our EZID (easy-eye-dee) identifier service. A data paper is a somewhat unfamiliar bundle of scholarly output with a familiar facade: minimally, a set of links to archived artifacts and a cover sheet containing familiar elements such as title, authors, date, abstract, and persistent identifier _ just enough to create basic citations, build "overlay journals", and enable discovery of data by internet search engines. Over time, we expect to add elements that permit deeper domain-specific discovery and re-use, such as variable names, methods, etc. At the same time, for data and identifiers that we manage, we will leverage as much domain-agnosticism data and identifier as possible.

  11. Acute Toxicity of a Recently Identified Phenol-based Synthetic ...

    African Journals Online (AJOL)

    This paper reports on the acute toxicity of a new phenol based synthetic tsetse fly repellent recently identified at the International Centre for Insect Physiology and Ecology (patent No. ... The repellent can be classified as being highly toxic with central nervous system (CNS) involvement and a mild skin and eye irritant.

  12. Image coding based on maximum entropy partitioning for identifying ...

    Indian Academy of Sciences (India)

    A new coding scheme based on maximum entropy partitioning is proposed in our work, particularly to identify the improbable intensities related to different emotions. The improbable intensities when used as a mask decode the facial expression correctly, providing an effectiveplatform for future emotion categorization ...

  13. Identifying desertification risk areas using fuzzy membership and ...

    Indian Academy of Sciences (India)

    2Birla Institute of Technology, Mesra, Ranchi 835 215, India. 3Indira Gandhi National Open ... Present research intends to identify the areas under risk of desertification along with their severity in terms of degradation in natural parameters. ... their risk severity in order to mitigate the effects of desertification. The conventional ...

  14. Transracial Adoption: Families Identify Issues and Needed Support Services. (United States)

    Vidal de Haymes, Maria; Simon, Shirley


    The gap between the number of children of color in care and the recruitment of minority foster and adoptive homes has triggered growing support for transracial adoption. This study explored a number of transracial placements and adoptions, with the goal of identifying, from the perspective of the families interviewed, potential services that would…

  15. Identifying the Key Weaknesses in Network Security at Colleges. (United States)

    Olsen, Florence


    A new study identifies and ranks the 10 security gaps responsible for most outsider attacks on college computer networks. The list is intended to help campus system administrators establish priorities as they work to increase security. One network security expert urges that institutions utilize multiple security layers. (DB)

  16. Identifying targets for quality improvement in hospital antibiotic prescribing

    NARCIS (Netherlands)

    Spreuwel, P.C. van; Blok, H.; Langelaar, M.F.; Kullberg, B.J.; Mouton, J.W.; Natsch, S.S.


    OBJECTIVES: To audit antibiotic use in a university hospital and to identify targets for quality improvement in a setting with low antibiotic use and resistance rates. METHODOLOGY: A point-prevalence survey (PPS), using a patient-based audit tool for antibiotic use, was executed in the Radboud

  17. From control system security indices to attack identifiability

    NARCIS (Netherlands)

    Herdeiro Teixeira, A.M.; Sandberg, H


    In this paper, we investigate detectability and identifiability of attacks on linear dynamical systems that are subjected to external disturbances. We generalize a concept for a security index, which was previously introduced for static systems. The index exactly quantifies the resources

  18. Inclusive education in Tanzania: Are all learners identified and their ...

    African Journals Online (AJOL)

    Eleven percent of all the participants had other eye conditions such as cataracts and amblyopia, which could lead to visual disabilities if not identified and treated early. The results of this study indicate that although Tanzania has set about establishing inclusive schools, the special needs of all children are not known ...

  19. Identifying Importance-Performance Matrix Analysis (IPMA) of ...

    African Journals Online (AJOL)

    The results of the study revealed that human capital, organizational capital, technological capital and Islamic work ethics significantly influenced business performance. Then, this study explored the use of the Importance-Performance matrix analysis to identify priority factors that can be enhanced to increase business ...

  20. Identifying Outpatients with Entrenched Suicidal Ideation Following Hospitalization (United States)

    O'Connor, Stephen S.; Jobes, David A.; Comtois, Katherine Anne; Atkins, David C.; Janis, Karin; Chessen, Chloe E.; Landes, Sara J.


    The purpose of this study was to identify outpatients who experience entrenched suicidal ideation following inpatient psychiatric hospitalization. Our findings suggest that the use of a suicidal ambivalence index score was helpful at discriminating those who reported significantly greater ratings of suicidal ideation across a 1-year period of…

  1. Identifying cognitive predictors of reactive and proactive aggression

    NARCIS (Netherlands)

    Brugman, S.; Lobbestael, J.; Arntz, A.; Cima, M.; Schuhmann, T.; Dambacher, F.; Sack, A.T.


    The aim of this study was to identify implicit cognitive predictors of aggressive behavior. Specifically, the predictive value of an attentional bias for aggressive stimuli and automatic association of the self and aggression was examined for reactive and proactive aggressive behavior in a

  2. Identifying Students’ Misconceptions on Basic Algorithmic Concepts Through Flowchart Analysis

    NARCIS (Netherlands)

    Rahimi, E.; Barendsen, E.; Henze, I.; Dagienė, V.; Hellas, A.


    In this paper, a flowchart-based approach to identifying secondary school students’ misconceptions (in a broad sense) on basic algorithm concepts is introduced. This approach uses student-generated flowcharts as the units of analysis and examines them against plan composition and construct-based

  3. Identifying Future Disease Hot Spots: Infectious Disease Vulnerability Index. (United States)

    Moore, Melinda; Gelfeld, Bill; Okunogbe, Adeyemi; Paul, Christopher


    Recent high-profile outbreaks, such as Ebola and Zika, have illustrated the transnational nature of infectious diseases. Countries that are most vulnerable to such outbreaks might be higher priorities for technical support. RAND created the Infectious Disease Vulnerability Index to help U.S. government and international agencies identify these countries and thereby inform programming to preemptively help mitigate the spread and effects of potential transnational outbreaks. The authors employed a rigorous methodology to identify the countries most vulnerable to disease outbreaks. They conducted a comprehensive review of relevant literature to identify factors influencing infectious disease vulnerability. Using widely available data, the authors created an index for identifying potentially vulnerable countries and then ranked countries by overall vulnerability score. Policymakers should focus on the 25 most-vulnerable countries with an eye toward a potential "disease belt" in the Sahel region of Africa. The infectious disease vulnerability scores for several countries were better than what would have been predicted on the basis of economic status alone. This suggests that low-income countries can overcome economic challenges and become more resilient to public health challenges, such as infectious disease outbreaks.

  4. Identifying digital records in business systems: the definition of a ...

    African Journals Online (AJOL)

    Before digital records can be preserved or managed, they need to be identified first. However, records identification is not a clearly defined process. Given the multi-faceted information system environment in organisations, large quantities of potential records are created and stored in systems not designed for records ...

  5. 44 CFR 5.27 - Deletion of identifying details. (United States)


    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Deletion of identifying... Availability of General Agency Information, Rules, Orders, Policies, and Similar Material § 5.27 Deletion of..., interpretation, or staff manual or instruction. However, the justification for each deletion will be explained...

  6. A novel scientific approach in identifying talents among female ...

    African Journals Online (AJOL)

    This study determine the most significant physical fitness and anthro-energy intake components in identifying the talents among female adolescent field hockey players. 45 players from Terengganu sport academy were assessed in physical fitness and anthro-energy intake measurements. The first rotated PCAs presented 8 ...

  7. Identifying market opportunities for Smallholder farmers in Uganda

    African Journals Online (AJOL)


    well-developed market infrastructure. One of the pillars of the .... A total of over 60 products were identified as either being in high demand or scarce ... Meat roasters and local butcheries. Small supermarkets, shops and kiosks. Large supermarkets. Hotels and restaurants. Street vendors. Institutions. Agri-food processors ...

  8. Nuclear techniques to identify allergenic metals in orthodontic brackets

    International Nuclear Information System (INIS)

    Zenobio, E.G.; Zenobio, M.A.F.; Menezes, M.A.B.C.


    The present study determines the elementary alloy composition of ten commercial brands of brackets, especially related to Ni, Cr, and Co metals, confirmed allergenic elements. The nuclear techniques applied in the analyses were X-ray fluorescence (XRF) - Centre National de la Recherche Scientifique, France (National Center of Scientific Research), and X-ray energy spectrometry (XRES), and Instrumental Neutron Activation Analysis (INAA) - CDTN/CNEN, Brazil. The XRES and XRF techniques identified Cr in the 10 samples analyzed and Ni in eight samples. The INAA technique identified the presence of Cr (14% to 19%) and Co (42% to 2400 ppm) in all samples. The semi-quantitative analysis performed by XRF also identified Co in two samples. The techniques were effective in the identification of metals in orthodontic brackets. The elements identified in this study can be considered one of the main reason for the allergic processes among the patients studied. This finding suggests that the patients should be tested for allergy and allergenic sensibility to metals prior to the prescription of orthodontic device. (author)

  9. Protein Correlation Profiles Identify Lipid Droplet Proteins with High Confidence* (United States)

    Krahmer, Natalie; Hilger, Maximiliane; Kory, Nora; Wilfling, Florian; Stoehr, Gabriele; Mann, Matthias; Farese, Robert V.; Walther, Tobias C.


    Lipid droplets (LDs) are important organelles in energy metabolism and lipid storage. Their cores are composed of neutral lipids that form a hydrophobic phase and are surrounded by a phospholipid monolayer that harbors specific proteins. Most well-established LD proteins perform important functions, particularly in cellular lipid metabolism. Morphological studies show LDs in close proximity to and interacting with membrane-bound cellular organelles, including the endoplasmic reticulum, mitochondria, peroxisomes, and endosomes. Because of these close associations, it is difficult to purify LDs to homogeneity. Consequently, the confident identification of bona fide LD proteins via proteomics has been challenging. Here, we report a methodology for LD protein identification based on mass spectrometry and protein correlation profiles. Using LD purification and quantitative, high-resolution mass spectrometry, we identified LD proteins by correlating their purification profiles to those of known LD proteins. Application of the protein correlation profile strategy to LDs isolated from Drosophila S2 cells led to the identification of 111 LD proteins in a cellular LD fraction in which 1481 proteins were detected. LD localization was confirmed in a subset of identified proteins via microscopy of the expressed proteins, thereby validating the approach. Among the identified LD proteins were both well-characterized LD proteins and proteins not previously known to be localized to LDs. Our method provides a high-confidence LD proteome of Drosophila cells and a novel approach that can be applied to identify LD proteins of other cell types and tissues. PMID:23319140

  10. Identifying wrong assemblies in de novo short read primary ...

    Indian Academy of Sciences (India)

    The present work also proposes a simpleunsupervised learning-based novel approach to identify mis-assemblies in the contigs which was found performingreasonably well when compared to the already existing tools to report mis-assembled contigs. It was observed that theproposed methodology may work as a ...

  11. Hyperspectral imaging to identify salt-tolerant wheat lines (United States)

    In order to address the worldwide growing demand for food, agriculture is facing certain challenges and limitations. One of the important threats limiting crop productivity is salinity. Identifying salt tolerate varieties is crucial to mitigate the negative effects of this abiotic stress in agricult...

  12. Effectiveness of a structured checklist of risk factors in identifying ...

    African Journals Online (AJOL)

    Background: Gestational diabetes mellitus (GDM) is associated with increased risk of mortality and morbidity for pregnant women and newborns. Identifying pregnant women with risk factors for GDM based on the clinical suspicion is a popular approach. However, the effectiveness of the use of a structured checklist of risk ...

  13. Identifying clinical course patterns in SMS data using cluster analysis

    DEFF Research Database (Denmark)

    Kent, Peter; Kongsted, Alice


    ABSTRACT: BACKGROUND: Recently, there has been interest in using the short message service (SMS or text messaging), to gather frequent information on the clinical course of individual patients. One possible role for identifying clinical course patterns is to assist in exploring clinically importa...

  14. Cyanobacteria species identified in the Weija and Kpong reservoirs ...

    African Journals Online (AJOL)

    The Kpong and Weija reservoirs supply drinking water to Accra, Ghana. This study was conducted to identify the cyanobacteria present in these reservoirs and to ascertain whether current treatment processes remove whole cyanobacteria cells from the drinking water produced. Cyanotoxins are mostly cell bound and could ...

  15. 75 FR 60309 - Furnishing Identifying Number of Tax Return Preparer (United States)


    ... identifying number unless the IRS directs otherwise. For tax returns or claims for refund filed before January... tax return or claim for refund of tax. The final regulations retain this definition from the proposed.... Consistent with the definition of a tax return preparer under section 7701(a)(36), which requires a...

  16. Identifying sensitive issues in education in Limpopo province, South ...

    African Journals Online (AJOL)

    ... significant mediators in principals' perceptions of sensitive issues in school management. When researchers wish to elicit information on the issues identified in this study, they should consider methodological issues that may influence the investigation so that understanding and giving voice and visibility is not jeopardized ...

  17. How to Identify and Forecast Bull and Bear Markets?

    NARCIS (Netherlands)

    H.J.W.G. Kole (Erik); D.J.C. van Dijk (Dick)


    textabstractThe state of the equity market, often referred to as a bull or a bear market, is of key importance for financial decisions and economic analyses. Its latent nature has led to several methods to identify past and current states of the market and forecast future states. These methods

  18. Identifying key processes in the hydrochemistry of a basin through ...

    Indian Academy of Sciences (India)

    Two key parameters were identified with each of the processes and multiple regression models were developed for each process. These models were tested and found to predict these processes quite accurately, and can be applied anywhere within the terrain. This technique can be reliably applied in areas where logistical ...

  19. Identifying factors affecting about outsourcing in paraclinical services

    African Journals Online (AJOL)

    Objective: Outsourcing refers to the transfer of services or functions to an outsider supplier, which controls them through a contract or cooperative. The main problem of senior managers in health organizations is determining the services which should be outsourced. The present study seeks to identify the factors that affect ...

  20. Symptom-based questionnaire for identifying COPD in smokers

    NARCIS (Netherlands)

    Price, David B.; Tinkelman, David G.; Halbert, R. J.; Nordyke, Robert J.; Isonaka, Sharon; Nonikov, Dmitry; Juniper, Elizabeth F.; Freeman, Daryl; Hausen, Thomas; Levy, Mark L.; Ostrem, Anders; van der Molen, Thys; van Schayck, Constant P.


    Background: Symptom-based questionnaires may enhance chronic obstructive pulmonary disease (COPD) screening in primary care. Objectives: We prospectively tested questions to help identify COPD among smokers without prior history of lung disease. Methods: Subjects were recruited via random mailing to