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Sample records for type iia supergravity

  1. Massive type IIA supergravity and E10

    International Nuclear Information System (INIS)

    Henneaux, M.; Kleinschmidt, A.; Persson, D.; Jamsin, E.

    2009-01-01

    In this talk we investigate the symmetry under E 10 of Romans' massive type IIA supergravity. We show that the dynamics of a spinning particle in a non-linear sigma model on the coset space E 10 /K(E 10 ) reproduces the bosonic and fermionic dynamics of massive IIA supergravity, in the standard truncation. In particular, we identify Romans' mass with a generator of E 10 that is beyond the realm of the generators of E 10 considered in the eleven-dimensional analysis, but using the same, underformed sigma model. As a consequence, this work provides a dynamical unification of the massless and massive versions of type IIA supergravity inside E 10 . (Abstract Copyright [2009], Wiley Periodicals, Inc.)

  2. 10D massive type IIA supergravities as the uplift of parabolic M2-brane torus bundles

    Energy Technology Data Exchange (ETDEWEB)

    Garcia del Moral, Maria Pilar [Universidad de Antofagasta (Chile). Dept. de Fisica; Restuccia, Alvaro [Universidad de Antofagasta (Chile). Dept. de Fisica; Universidad Simon Bolivar, Caracas (Venezuela, Bolivarian Republic of). Dept. de Fisica

    2016-04-15

    We remark that the two 10D massive deformations of the N = 2 maximal type IIA supergravity (Romans and HLW supergravity) are associated to the low energy limit of the uplift to 10D of M2-brane torus bundles with parabolic monodromy linearly and non-linearly realized respectively. Romans supergravity corresponds to M2-brane compactified on a twice-punctured torus bundle. (copyright 2015 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  3. Type IIA on a compact Calabi-Yau and D=11 supergravity uplift of its orientifold

    International Nuclear Information System (INIS)

    Misra, A.

    2004-01-01

    Using the prescription of K. Hori and C. Vafa for defining period integrals in the Landau-Ginsburg theory for compact Calabi-Yau's, we obtain the Picard-Fuchs equation and the Meijer basis of solutions for the compact Calabi-Yau CY 3 (3,243) expressed as a degree-24 Fermat hypersurface after resolution of the orbifold singularities. The importance of the method lies in the ease with which one can consider the large and small complex structure limits, as well as the ability to get the ''ln''-terms in the periods without having to parametrically differentiate infinite series. We consider in detail the evaluation of the monodromy matrix in the large and small complex structure limits. We also consider the action of the freely acting antiholomorphic involution on D=11 supergravity compactified on CY 3 (3,243) x S 1 and obtain the Kaehler potential for the same in the limit of large volume of the Calabi-Yau. As a by-product, we also give a conjecture for the action of the orientation-reversing antiholomorphic involution on the periods, given its action on the cohomology, using a canonical (co)homology basis. Finally, we also consider showing a null superpotential on the orientifold of type IIA on CY 3 (3,243), having taken care of the orbifold singularities. (Abstract Copyright [2004], Wiley Periodicals, Inc.)

  4. Compactifications of IIA supergravity on SU(2)-structure manifolds

    Energy Technology Data Exchange (ETDEWEB)

    Spanjaard, B.

    2008-07-15

    In this thesis, we study compactifications of type IIA supergravity on six-dimensional manifolds with an SU(2)-structure. A general study of six-dimensional manifolds with SU(2)-structure shows that IIA supergravity compactified on such a manifold should yield a four-dimensional gauged N=4 supergravity. We explicitly derive the bosonic spectrum, gauge transformations and action for IIA supergravity compactified on two different manifolds with SU(2)-structure, one of which also has an H{sup (3)}{sub 10}-flux, and confirm that the resulting four-dimensional theories are indeed N=4 gauged supergravities. In the second chapter, we study an explicit construction of a set of SU(2)-structure manifolds. This construction involves a Scherk-Schwarz duality twist reduction of the half-maximal six-dimensional supergravity obtained by compactifying IIA supergravity on a K3. This reduction results in a gauged N=4 four-dimensional supergravity, where the gaugings can be divided into three classes of parameters. We relate two of the classes to parameters we found before, and argue that the third class of parameters could be interpreted as a mirror flux. (orig.)

  5. Deformed N = 8 supergravity from IIA strings and its Chern-Simons duals

    Energy Technology Data Exchange (ETDEWEB)

    Guarino, Adolfo [Nikhef Theory Group, Amsterdam (Netherlands); Jafferis, Daniel L. [Center for the Fundamental Laws of Nature, Harvard University, Cambridge, MA (United States); Varela, Oscar [Center for the Fundamental Laws of Nature, Harvard University, Cambridge, MA (United States); Centre de Physique Theorique, Ecole Polytechnique, CNRS UMR 7644, Palaiseau (France)

    2016-04-15

    Do electric/magnetic deformations of N = 8 supergravity enjoy a string/M-theory origin, or are they just a fourdimensional artefact? We address this question for the gauging of a group closely related to SO(8): its contraction ISO(7). We argue that the deformed ISO(7) supergravity arises from consistent truncation of massive IIA supergravity on S{sup 6}, and its electric/magnetic deformation parameter descends directly from the Romans mass. The critical points of the supergravity uplift to AdS{sub 4} massive type IIA vacua and the corresponding CFT{sub 3} duals are identified as super-Chern-Simons-matter theories with gauge group SU(N) and level k given also by the Romans mass. (copyright 2015 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  6. Supersymmetric geometries of IIA supergravity III

    International Nuclear Information System (INIS)

    Gran, Ulf; Papadopoulos, George; Schultz, Christian von

    2016-01-01

    We find that (massive) IIA backgrounds that admit a G 2 ⋉ℝ 8 invariant Killing spinor must exhibit a null Killing vector field which leaves the Killing spinor invariant and that the rotation of the Killing vector field satisfies a certain g 2 instanton condition. This result together with those in http://dx.doi.org/10.1007/JHEP05(2014)024 and http://dx.doi.org/10.1007/JHEP12(2015)113 complete the classification of geometries of all (massive) IIA backgrounds that preserve one supersymmetry. We also explore the geometry of a class of backgrounds which admit a G 2 ⋉ℝ 8 invariant Killing spinor and where in addition an appropriate 1-form bilinear vanishes. In all cases, we express the fluxes of the theory in terms of the geometry.

  7. Attractor horizons in six-dimensional type IIB supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Astefanesei, Dumitru, E-mail: dumitru.astefanesei@ucv.cl [Instituto de Fisica, Pontificia Universidad Catolica de Valparaiso, Casilla 4059, Valparaiso (Chile); Miskovic, Olivera, E-mail: olivera.miskovic@ucv.cl [Instituto de Fisica, Pontificia Universidad Catolica de Valparaiso, Casilla 4059, Valparaiso (Chile); Olea, Rodrigo, E-mail: rodrigo.olea@unab.cl [Universidad Andres Bello, Departamento de Ciencias Fisicas, Republica 220, Santiago (Chile)

    2012-08-14

    We consider near horizon geometries of extremal black holes in six-dimensional type IIB supergravity. In particular, we use the entropy function formalism to compute the charges and thermodynamic entropy of these solutions. We also comment on the role of attractor mechanism in understanding the entropy of the Hopf T-dual solutions in type IIA supergravity.

  8. de Sitter space from dilatino condensates in massive IIA supergravity

    Science.gov (United States)

    Souères, Bertrand; Tsimpis, Dimitrios

    2018-02-01

    We use the superspace formulation of (massive) IIA supergravity to obtain the explicit form of the dilatino terms, and we find that the quartic-dilatino term is positive. The theory admits a ten-dimensional de Sitter solution, obtained by assuming a nonvanishing quartic-dilatino condensate which generates a positive cosmological constant. Moreover, in the presence of dilatino condensates, the theory admits formal four-dimensional de Sitter solutions of the form d S4×M6, where M6 is a six-dimensional Kähler-Einstein manifold of positive scalar curvature.

  9. Type IIA orientifolds on SU(2)-structure manifolds

    Energy Technology Data Exchange (ETDEWEB)

    Danckaert, Thomas

    2010-11-15

    We investigate the possible supersymmetry-preserving orientifold projections of type IIA string theory on a six-dimensional background with SU(2)-structure. We find two categories of projections which preserve half of the low-energy supersymmetry, reducing the effective theory from an N=4 supergravity theory, to an N=2 supergravity. For these two cases, we impose the projection on the low-energy spectrum and reduce the effective N=4 supergravity action accordingly. We can identify the resulting gauged N=2 supergravity theory and bring the action into canonical form. We compute the scalar moduli spaces and characterize the gauged symmetries in terms of the geometry of these moduli spaces. Due to their origin in N=4 supergravity, which is a highly constrained theory, the moduli spaces are of a very simple form. We find that, for suitable background manifolds, isometries in all scalar sectors can become gauged. The obtained gaugings share many features with those of N=2 supergravities obtained previously from other G-structure compactifications. (orig.)

  10. Massive deformations of Type IIA theory within double field theory

    Science.gov (United States)

    Çatal-Özer, Aybike

    2018-02-01

    We obtain massive deformations of Type IIA supergravity theory through duality twisted reductions of Double Field Theory (DFT) of massless Type II strings. The mass deformation is induced through the reduction of the DFT of the RR sector. Such reductions are determined by a twist element belonging to Spin+(10, 10), which is the duality group of the DFT of the RR sector. We determine the form of the twists and give particular examples of twists matrices, for which a massive deformation of Type IIA theory can be obtained. In one of the cases, requirement of gauge invariance of the RR sector implies that the dilaton field must pick up a linear dependence on one of the dual coordinates. In another case, the choice of the twist matrix violates the weak and the strong constraints explicitly in the internal doubled space.

  11. Hypermultiplet gaugings and supersymmetric solutions from 11D and massive IIA supergravity on H^{(p,q)} spaces

    Science.gov (United States)

    Guarino, Adolfo

    2018-03-01

    Supersymmetric {AdS}4, {AdS}2 × Σ 2 and asymptotically AdS4 black hole solutions are studied in the context of non-minimal N=2 supergravity models involving three vector multiplets (STU-model) and Abelian gaugings of the universal hypermultiplet moduli space. Such models correspond to consistent subsectors of the {SO}(p,q) and {ISO}(p,q) gauged maximal supergravities that arise from the reduction of 11D and massive IIA supergravity on {H}^{(p,q)} spaces down to four dimensions. A unified description of all the models is provided in terms of a square-root prepotential and the gauging of a duality-hidden symmetry pair of the universal hypermultiplet. Some aspects of M-theory and massive IIA holography are mentioned in passing.

  12. Audiological findings in Usher syndrome types IIa and II (non-IIa).

    Science.gov (United States)

    Sadeghi, Mehdi; Cohn, Edward S; Kelly, William J; Kimberling, William J; Tranebjoerg, Lisbeth; Möller, Claes

    2004-03-01

    The aim was to define the natural history of hearing loss in Usher syndrome type IIa compared to non-IIa. People with Usher syndrome type II show moderate-to-severe hearing loss, normal balance and retinitis pigmentosa. Several genes cause Usher syndrome type II. Our subjects formed two genetic groups: (1) subjects with Usher syndrome type IIa with a mutation and/or linkage to the Usher IIa gene; (2) subjects with the Usher II phenotype with no mutation and/or linkage to the Usher IIa gene. Four hundred and two audiograms of 80 Usher IIa subjects were compared with 435 audiograms of 87 non-IIa subjects. Serial audiograms with intervals of > or = 5 years were examined for progression in 109 individuals Those with Usher syndrome type IIa had significantly worse hearing thresholds than those with non-IIa Usher syndrome after the second decade. The hearing loss in Usher syndrome type IIa was found to be more progressive, and the progression started earlier than in non-IIa Usher syndrome. This suggests an auditory phenotype for Usher syndrome type IIa that is different from that of other types of Usher syndrome II. Thus, this is to our knowledge one of the first studies showing a genotype-phenotype auditory correlation.

  13. Supergravity

    International Nuclear Information System (INIS)

    Witt, B. de

    2002-01-01

    It is a comprehensive introduction to supergravities in different dimensions and with various numbers of supersymmetries. Topics covered include the allowed low-energy couplings, duality symmetries, compactification and supersymmetries in curved backgrounds. This document is made up of 7 chapters: 1) introduction, 2) supersymmetry in various dimensions, 3) supergravity, 4) homogeneous spaces and non-linear sigma models, 5) gauged maximal supergravity in 4 and 5 dimensions, 6) supersymmetry in anti-Sitter space, and 7) superconformal symmetry. (A.C.)

  14. Supergravity

    CERN Document Server

    Freedman, Daniel Z

    2012-01-01

    Supergravity, together with string theory, is one of the most significant developments in theoretical physics. Written by two of the most respected workers in the field, this is the first-ever authoritative and systematic account of supergravity. The book starts by reviewing aspects of relativistic field theory in Minkowski spacetime. After introducing the relevant ingredients of differential geometry and gravity, some basic supergravity theories (D=4 and D=11) and the main gauge theory tools are explained. In the second half of the book, complex geometry and N=1 and N=2 supergravity theories are covered. Classical solutions and a chapter on AdS/CFT complete the book. Numerous exercises and examples make it ideal for Ph.D. students, and with applications to model building, cosmology and solutions of supergravity theories, it is also invaluable to researchers.

  15. Type IIA flux compactifications. Vacua, effective theories and cosmological challenges

    International Nuclear Information System (INIS)

    Koers, Simon

    2009-01-01

    In this thesis, we studied a number of type IIA SU(3)-structure compactifications with 06-planes on nilmanifolds and cosets, which are tractable enough to allow for an explicit derivation of the low energy effective theory. In particular we calculated the mass spectrum of the light scalar modes, using N = 1 supergravity techniques. For the torus and the Iwasawa solution, we have also performed an explicit Kaluza-Klein reduction, which led to the same result. For the nilmanifold examples we have found that there are always three unstabilized moduli corresponding to axions in the RR sector. On the other hand, in the coset models, except for SU(2) x SU(2), all moduli are stabilized. We discussed the Kaluza-Klein decoupling for the supersymmetric AdS vacua and found that it requires going to the Nearly-Calabi Yau limited. We searched for non-trivial de Sitter minima in the original flux potential away from the AdS vacuum. Finally, in chapter 7, we focused on a family of three coset spaces and constructed non-supersymmetric vacua on them. (orig.)

  16. Ambitwistor pure spinor string in a type II supergravity background

    Energy Technology Data Exchange (ETDEWEB)

    Chandia, Osvaldo [Departamento de Ciencias, Facultad de Artes Liberales, Universidad Adolfo Ibáñez,Facultad de Ingeniería y Ciencias, Universidad Adolfo Ibáñez,Diagonal Las Torres 2640, Peñalolén, Santiago (Chile); Vallilo, Brenno Carlini [Departamento de Ciencias Físicas, Facultad de Ciencias Exactas, Universidad Andres Bello,República 220, Santiago (Chile)

    2015-06-30

    We construct the ambitwistor pure spinor string in a general type II supergravity background in the semi-classical regime. Almost all supergravity constraints are obtained from nilpotency of the BRST charge and further consistency conditions from additional world-sheet the case of AdS{sub 5}×S{sup 5} background.

  17. N=1 domain wall solutions of massive type II supergravity as generalized geometries

    International Nuclear Information System (INIS)

    Louis, J.

    2006-05-01

    We study N=1 domain wall solutions of type IIB supergravity compactified on a Calabi-Yau manifold in the presence of RR and NS electric and magnetic fluxes. We show that the dynamics of the scalar fields along the direction transverse to the domain wall is described by gradient flow equations controlled by a superpotential W. We then provide a geometrical interpretation of the gradient flow equations in terms of the mirror symmetric compactification of type IIA. They correspond to a set of generalized Hitchin flow equations of a manifold with SU(3) x SU(3)structure which is fibered over the direction transverse to the domain wall. (Orig.)

  18. Moduli Potentials in Type IIA Compactifications with RR and NS Flux

    Energy Technology Data Exchange (ETDEWEB)

    Kachru, S.

    2004-12-01

    We describe a simple class of type IIA string compactifications on Calabi-Yau manifolds where background fluxes generate a potential for the complex structure moduli, the dilaton, and the Kaehler moduli. This class of models corresponds to gauged {Nu} = 2 supergravities, and the potential is completely determined by a choice of gauging and by data of the {Nu} = 2 Calabi-Yau model--the prepotential for vector multiplets and the quaternionic metric on the hypermultiplet moduli space. Using mirror symmetry, one can determine many (though not all) of the quantum corrections which are relevant in these models.

  19. Generalized IIB supergravity from exceptional field theory

    Energy Technology Data Exchange (ETDEWEB)

    Baguet, Arnaud; Magro, Marc; Samtleben, Henning [Laboratoire de Physique, Université Claude Bernard Lyon 1, Ens de Lyon, CNRS,F-69342 Lyon (France)

    2017-03-20

    The background underlying the η-deformed AdS{sub 5}×S{sup 5} sigma-model is known to satisfy a generalization of the IIB supergravity equations. Their solutions are related by T-duality to solutions of type IIA supergravity with non-isometric linear dilaton. We show how the generalized IIB supergravity equations can be naturally obtained from exceptional field theory. Within this manifestly duality covariant formulation of maximal supergravity, the generalized IIB supergravity equations emerge upon imposing on the fields a simple Scherk-Schwarz ansatz which respects the section constraint.

  20. Non-renormalisation conditions in type II string theory and maximal supergravity

    International Nuclear Information System (INIS)

    Green, Michael B.; Russo, Jorge G.; Vanhove, Pierre

    2007-01-01

    This paper considers general features of the derivative expansion of Feynman diagram contributions to the four-graviton scattering amplitude in eleven-dimensional supergravity compactified on a two-torus. These are translated into statements about interactions of the form D 2k R 4 in type II superstring theories, assuming the standard M-theory/string theory duality relationships, which provide powerful constraints on the effective interactions. In the ten-dimensional IIA limit we find that there can be no perturbative contributions beyond k string loops (for k>0). Furthermore, the genus h = k contributions are determined exactly by the one-loop eleven-dimensional supergravity amplitude for all values of k. A plausible interpretation of these observations is that the sum of h-loop Feynman diagrams of maximally extended supergravity is less divergent than might be expected and could be ultraviolet finite in dimensions d<4+6/h - the same bound as for N = 4 Yang-Mills

  1. Non-renormalisation conditions in type II string theory and maximal supergravity

    Science.gov (United States)

    Green, Michael B.; Russo, Jorge G.; Vanhove, Pierre

    2007-02-01

    This paper considers general features of the derivative expansion of Feynman diagram contributions to the four-graviton scattering amplitude in eleven-dimensional supergravity compactified on a two-torus. These are translated into statements about interactions of the form D2kR4 in type II superstring theories, assuming the standard M-theory/string theory duality relationships, which provide powerful constraints on the effective interactions. In the ten-dimensional IIA limit we find that there can be no perturbative contributions beyond k string loops (for k>0). Furthermore, the genus h = k contributions are determined exactly by the one-loop eleven-dimensional supergravity amplitude for all values of k. A plausible interpretation of these observations is that the sum of h-loop Feynman diagrams of maximally extended supergravity is less divergent than might be expected and could be ultraviolet finite in dimensions d<4+6/h - the same bound as for N = 4 Yang-Mills.

  2. Starobinsky-type Inflation in Dynamical Supergravity Breaking Scenarios

    CERN Document Server

    Alexandre, Jean; Mavromatos, Nick E.

    2014-01-27

    In the context of dynamical breaking of local supersymmetry (supergravity), including the Deser-Zumino super-Higgs effect, for the simple but quite representative cases of N=1, D=4 supergravity, we discuss the emergence of Starobinsky-type inflation, due to quantum corrections in the effective action arising from integrating out gravitino fields in their massive phase. This type of inflation may occur after a first-stage small-field inflation that characterises models near the origin of the one-loop effective potential, and it may occur at the non-trivial minima of the latter. Phenomenologically realistic scenarios, compatible with the Planck data, may be expected for the conformal supergravity variants of the basic model.

  3. Supersymmetric AdS6 solutions of type IIB supergravity

    International Nuclear Information System (INIS)

    Kim, Hyojoong; Kim, Nakwoo; Suh, Minwoo

    2015-01-01

    We study the general requirement for supersymmetric AdS 6 solutions in type IIB supergravity. We employ the Killing spinor technique and study the differential and algebraic relations among various Killing spinor bilinears to find the canonical form of the solutions. Our result agrees precisely with the work of Apruzzi et al. (JHEP 1411:099, 2014), which used the pure spinor technique. Hoping to identify the geometry of the problem, we also computed four-dimensional theory through the dimensional reduction of type IIB supergravity on AdS 6 . This effective action is essentially a non-linear sigma model with five scalar fields parametrizing SL(3,ℝ)/SO(2,1), modified by a scalar potential and coupled to Einstein gravity in Euclidean signature. We argue that the scalar potential can be explained by a subgroup CSO(1,1,1) ⊂SL(3,ℝ) in a way analogous to gauged supergravity

  4. Invariant Killing spinors in 11D and type II supergravities

    International Nuclear Information System (INIS)

    Gran, U; Gutowski, J; Papadopoulos, G

    2009-01-01

    We present all isotropy groups and associated Σ groups, up to discrete identifications of the component connected to the identity, of spinors of 11-dimensional and type II supergravities. The Σ groups are products of a Spin group and an R-symmetry group of a suitable lower dimensional supergravity theory. Using the case of SU(4)-invariant spinors as a paradigm, we demonstrate that the Σ groups, and so the R-symmetry groups of lower dimensional supergravity theories arising from compactifications, have disconnected components. These lead us to discrete symmetry groups reminiscent of R-parity. We examine the role of disconnected components of the Σ groups in the choice of Killing spinor representatives and in the context of compactifications.

  5. Type I supergravity effective action from pure spinor formalism

    International Nuclear Information System (INIS)

    Alencar, Geova

    2009-01-01

    Using the pure spinor formalism, we compute the tree-level correlation functions for three strings, one closed and two open, in N = 1 D = 10 superspace. Expanding the superfields in components, the respective terms of the effective action for the type I supergravity are obtained. All terms found agree with the effective action known in the literature. This result gives one more consistency test for the pure spinor formalism.

  6. Vertex operators of ghost number three in Type IIB supergravity

    International Nuclear Information System (INIS)

    Mikhailov, Andrei

    2016-01-01

    We study the cohomology of the massless BRST complex of the Type IIB pure spinor superstring in flat space. In particular, we find that the cohomology at the ghost number three is nontrivial and transforms in the same representation of the supersymmetry algebra as the solutions of the linearized classical supergravity equations. Modulo some finite dimensional spaces, the ghost number three cohomology is the same as the ghost number two cohomology. We also comment on the difference between the naive and semi-relative cohomology, and the role of b-ghost.

  7. Massive IIA string theory and Matrix theory compactification

    International Nuclear Information System (INIS)

    Lowe, David A.; Nastase, Horatiu; Ramgoolam, Sanjaye

    2003-01-01

    We propose a Matrix theory approach to Romans' massive Type IIA supergravity. It is obtained by applying the procedure of Matrix theory compactifications to Hull's proposal of the massive Type IIA string theory as M-theory on a twisted torus. The resulting Matrix theory is a super-Yang-Mills theory on large N three-branes with a space-dependent noncommutativity parameter, which is also independently derived by a T-duality approach. We give evidence showing that the energies of a class of physical excitations of the super-Yang-Mills theory show the correct symmetry expected from massive Type IIA string theory in a lightcone quantization

  8. Flipped and unflipped SU(5) as type IIA flux vacua

    Energy Technology Data Exchange (ETDEWEB)

    Chen Chingming [George P. and Cynthia W. Mitchell Institute for Fundamental Physics, Texas A and M University, College Station, TX 77843 (United States); Li Tianjun [Department of Physics and Astronomy, Rutgers University, Piscataway, NJ 08854 (United States) and Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 100080 (China)]. E-mail: tjli@physics.rutgers.edu; Nanopoulos, Dimitri V. [George P. and Cynthia W. Mitchell Institute for Fundamental Physics, Texas A and M University, College Station, TX 77843 (United States); Astroparticle Physics Group, Houston Advanced Research Center (HARC), Mitchell Campus, Woodlands, TX 77381 (United States); Academy of Athens, Division of Natural Sciences, 28 Panepistimiou Avenue, Athens 10679 (Greece)

    2006-09-04

    On type IIA orientifolds with flux compactifications in supersymmetric AdS vacua, we for the first time construct SU(5) models with three anti-symmetric 10 representations and without symmetric 15 representations. We show that all the pairs of the anti-fundamental 5-bar and fundamental 5 representations can obtain GUT/string-scale vector-like masses after the additional gauge symmetry breaking via supersymmetry preserving Higgs mechanism. Then we have exact three 5-bar , and no other chiral exotic particles that are charged under SU(5) due to the non-Abelian anomaly free condition. Moreover, we can break the SU(5) gauge symmetry down to the SM gauge symmetry via D6-brane splitting, and solve the doublet-triplet splitting problem. Assuming that the extra one (or several) pair(s) of Higgs doublets and adjoint particles obtain GUT/string-scale masses via high-dimensional operators, we only have the MSSM in the observable sector below the GUT scale. Then the observed low energy gauge couplings can be generated via RGE running if we choose the suitable grand unified gauge coupling by adjusting the string scale. Furthermore, we construct the first flipped SU(5) model with exact three 10, and the first flipped SU(5) model in which all the Yukawa couplings are allowed by the global U(1) symmetries.

  9. KK-monopoles and G-structures in M-theory/type IIA reductions

    International Nuclear Information System (INIS)

    Danielsson, Ulf; Dibitetto, Giuseppe; Guarino, Adolfo

    2015-01-01

    We argue that M-theory/massive IIA backgrounds including KK-monopoles are suitably described in the language of G-structures and their intrinsic torsion. To this end, we study classes of minimal supergravity models that admit an interpretation as twisted reductions in which the twist parameters are not restricted to satisfy the Jacobi constraints ω ω=0 required by an ordinary Scherk-Schwarz reduction. We first derive the correspondence between four-dimensional data and torsion classes of the internal space and, then, check the one-to-one correspondence between higher-dimensional and four-dimensional equations of motion. Remarkably, the whole construction holds regardless of the Jacobi constraints, thus shedding light upon the string/M-theory interpretation of (smeared) KK-monopoles.

  10. Superdualities, brane tensions and massive IIA/IIB duality

    International Nuclear Information System (INIS)

    Lavrinenko, I.V.; Lue, H.; Pope, C.N.; Stelle, K.S.

    1999-01-01

    The gauge transformations of p-form fields in supergravity theories acquire a non-commuting character when one introduces potentials both for the theory's original field strengths and for their duals. This has previously been shown in the 'doubled' formalism for maximal supergravities, where a generalised duality relation between original and dual field strengths replaces the equations of motion. In the doubled formalism, the gauge transformations generate a superalgebra, and the corresponding symmetries have accordingly been called 'superdualities'. The corresponding Noether charges form a representation of the cohomology ring on the space-time manifold. In this paper, we show that the gauge symmetry superalgebra implies certain non-trivial relations among the various p-brane tensions, which can straightforwardly be read off from the superalgebra commutation relations. This provides an elegant derivation of the brane-tension relations purely within a given theory, without the need to make use of duality relations between different theories, such as the type IIA/IIB T-duality, although the results are consistent with such dualities. We present the complete set of brane-tension relations in M-theory, in the type IIA and type IIB theories, and in all the lower-dimensional maximal supergravities. We also construct a doubled formalism for massive type IIA supergravity, and this enables us to obtain the brane-tension relations involving the D8-brane, purely within the framework of the massive IIA theory. We also obtain explicit transformations for the nine-dimensional T-duality between the massive type IIA theory and the Scherk-Schwarz reduced type IIB theory

  11. On $R^4$ terms and MHV amplitudes in N = 5,6 supergravity vacua of Type II superstrings

    CERN Document Server

    Bianchi, Massimo

    2011-01-01

    We compute one-loop threshold corrections to $R^4$ terms in N= 5,6 supergravity vacua of Type II superstrings. We then discuss non-perturbative corrections generated by asymmetric D-brane instantons. Finally we derive generating functions for MHV amplitudes at tree level in N = 5, 6 supergravities.

  12. Type IIA2 urethral duplication: report of an unusual case | Gupta ...

    African Journals Online (AJOL)

    This report describes a rare case of type IIA2 sagittal urethral duplication. The presentation, investigation, and management of this rare anomaly are briefly discussed. A 3½-year-old boy presented with urinary obstruction and recurrent urinary tract infection due to a stenosed dorsal urethra and segmental stenosis of the ...

  13. Cochlear Implantation in Patients With Usher Syndrome Type IIa Increases Performance and Quality of Life

    NARCIS (Netherlands)

    Hartel, B.P.; Nierop, J.W.I. van; Huinck, W.J.; Rotteveel, L.J.C.; Mylanus, E.A.M.; Snik, A.F.M.; Kunst, H.P.M.; Pennings, R.J.E.

    2017-01-01

    OBJECTIVES: Usher syndrome type IIa (USH2a) is characterized by congenital moderate to severe hearing impairment and retinitis pigmentosa. Hearing rehabilitation starts in early childhood with the application of hearing aids. In some patients with USH2a, severe progression of hearing impairment

  14. Supergravity solitons

    International Nuclear Information System (INIS)

    Aichelburg, P.C.; Embacher, F.

    1987-01-01

    The Langrangian for a single free soliton in N = 2 supergravity as proposed in an earlier paper, is studied. We analyze the algebra of constraints and discuss the local gauge symmetry due to the existence of first class constraints. The classical motion as well as a Gupta-Bleuler type quantization are given. (Author)

  15. Expression of Dihydropyridine and Ryanodine Receptors in Type IIA Fibers of Rat Skeletal Muscle

    International Nuclear Information System (INIS)

    Anttila, Katja; Mänttäri, Satu; Järvilehto, Matti

    2007-01-01

    In this study, the fiber type specificity of dihydropyridine receptors (DHPRs) and ryanodine receptors (RyRs) in different rat limb muscles was investigated. Western blot and histochemical analyses provided for the first time evidence that the expression of both receptors correlates to a specific myosin heavy chain (MHC) composition. We observed a significant (p=0.01) correlation between DHP as well as Ry receptor density and the expression of MHC IIa (correlation factor r=0.674 and r=0.645, respectively) in one slow-twitch, postural muscle (m. soleus), one mixed, fast-twitch muscle (m. gastrocnemius) and two fast-twitch muscles (m. rectus femoris, m. extensor digitorum longus). The highest DHP and Ry receptor density was found in the white part of m. rectus femoris (0.058±0.0060 and 0.057±0.0158 ODu, respectively). As expected, the highest relative percentage of MHC IIa was also found in the white part of m. rectus femoris (70.0±7.77%). Furthermore, histochemical experiments revealed that the IIA fibers stained most strongly for the fluorophore-conjugated receptor blockers. Our data clearly suggest that the expression of DHPRs and RyRs follows a fiber type-specific pattern, indicating an important role for these proteins in the maintenance of an effective Ca 2+ cycle in the fast contracting fiber type IIA

  16. Supergravity and superstrings

    International Nuclear Information System (INIS)

    Gell-Mann, M.

    1985-01-01

    The ''standard'' SU/sub 3/ x SU/sub 2/ x U/sub 1/ theory has three independent coupling constants and numerous dimensionless parameters determining mass ratios, the weak coupling matrix, etc. While N=1 supergravity, generalizing Einstein's gravity theory, is not necessarily very divergent itself, it is terribly divergent when coupled to external N=1 supermatter, such as N=1 super-Yang-Mills theory with N=1 supermultiplets of spin one-half and spin zero. Three paths are being explored in the search for the ultimate unified theory of physics. The first path involves N > 1 supergravity in four dimensions, without external supermatter, particularly the largest such theory, N=8 supergravity, where there is no room for external supermatter. The N=8 supergravity supermultiplet itself contains all the haplons (fundamental fields of the theory). During the last couple of years Michael Green and John Schwarz have found that there are two more 10-dimensional superstring theories IIA and IIB, with only closed strings. They reduce, on truncation to the initially massless actor, to N=2A and N=2B supergravity, respectively, in ten dimensions. But the superstring theories are finite to one loop instead of divergent like the corresponding supergravities. The author discusses that IIA and IIB superstrings, when truncated to the initially massless sector and trivially reduced to four dimensions, yield N=8 supergravity. All three superstring theories, although they have the traditional description as ''S-matrix'' theories on the mass shell, can also be written as field theories (with fields as functionals of strings instead of functions of points) with local couplings. So far, the field description is not covariant. This paper discusses various superstrings theories

  17. On Type IIB moduli stabilization and N=4,8 supergravities

    Energy Technology Data Exchange (ETDEWEB)

    Aldazabal, Gerardo [Centro Atomico Bariloche, Instituto Balseiro (CNEA-UNC) and CONICET, 8400 S.C. de Bariloche (Argentina); Marques, Diego [Institut de Physique Theorique, CEA/ Saclay, 91191 Gif-sur-Yvette Cedex (France); Nunez, Carmen, E-mail: carmen@iafe.uba.a [Instituto de Astronomia y Fisica del Espacio (CONICET-UBA) and Departamento de Fisica, FCEN, Universidad de Buenos Aires, C.C. 67 - Suc. 28, 1428 Buenos Aires (Argentina); Rosabal, Jose A. [Centro Atomico Bariloche, Instituto Balseiro (CNEA-UNC) and CONICET, 8400 S.C. de Bariloche (Argentina)

    2011-08-01

    We analyze D=4 compactifications of Type IIB theory with generic, geometric and non-geometric, dual fluxes turned on. In particular, we study N=1 toroidal orbifold compactifications that admit an embedding of the untwisted sector into gauged N=4,8 supergravities. Truncations, spontaneous breaking of supersymmetry and the inclusion of sources are discussed. The algebraic identities satisfied by the supergravity gaugings are used to implement the full set of consistency constraints on the background fluxes. This allows to perform a generic study of N=1 vacua and identify large regions of the parameter space that do not admit complete moduli stabilization. Illustrative examples of AdS and Minkowski vacua are presented.

  18. Differential diagnosis of gastric adenoma and type IIa early gastric cancer

    International Nuclear Information System (INIS)

    Tsuchigame, T.; Ogata, Y.; Sumi, M.; Fukui, K.; Saito, R.; Nakashima, K.; Urata, J.; Arakawa, A.; Saito, Y.; Takahashi, M.

    1991-01-01

    The endoscopic and radiographic findings of 45 gastric adenomas in 39 patients were followed for 6 months to 13 years and compared with type IIa early gastric cancer observed in 9 patients. Difficulties in the diffential diagnosis of these disorders were evaluated. The following features were suggestive of gastric adenomas: clustered lesions; protuberance with gentle slope; smooth surface; and relatively young patients. Discrimination of adenoma from type IIa early gastric cancer is often difficult by visual observation alone; biopsy was essential in most patients. A group III adenoma verified on biopsy should be followed closely because the lesion may harbor a cancer (so-called carcinoma-in-adenoma) or a cancer may later develop. (orig.)

  19. Focal cortical dysplasia type IIa and IIb: MRI aspects in 118 cases proven by histopathology

    Energy Technology Data Exchange (ETDEWEB)

    Colombo, Nadia; Citterio, Alberto [Ospedale Ca Granda Niguarda, Department of Neuroradiology, Milano (Italy); Tassi, Laura; Mai, Roberto; Sartori, Ivana; Cardinale, Francesco; Lo Russo, Giorgio [Ospedale Niguarda, Claudio Munari Epilepsy Surgery Center, Milano (Italy); Deleo, Francesco; Spreafico, Roberto [IRCCS Foundation Neurological Institute ' ' C. Besta' ' , Department of Epilepsy Clinic and Experimental Neurophysiology, Milano (Italy); Bramerio, Manuela [Ospedale Niguarda, Department of Pathology, Milano (Italy)

    2012-10-15

    This study aims to review the magnetic resonance imaging (MRI) aspects of a large series of patients with focal cortical dysplasia type II (FCD II) and attempt to identify distinctive features in the two histopathological subtypes IIa and IIb. We retrospectively reviewed the MRI scans of 118 patients with histological proven FCD IIa (n = 37) or IIb (n = 81) who were surgically treated for intractable epilepsy. MRI was abnormal in 93 patients (79 %) and unremarkable in 25 (21 %). A dysplastic lesion was identified in 90 cases (97 %) and classified as FCD II in 83 and FCD non-II in seven cases. In three cases, the MRI diagnosis was other than FCD. There was a significant association between the presence of cortical thickening (p = 0.002) and the ''transmantle sign'' (p < 0.001) and a correct MRI diagnosis of FCD II. MRI positivity was more frequent in the patients with FCD IIb than in those with FCD IIa (91 % vs. 51 %), and the detection rate of FCD II was also better in the patients with type IIb (88 % vs. 32 %). The transmantle sign was significantly more frequent in the IIb subgroup (p = 0.003). The rates of abnormal MRI results and correct MRI diagnoses of FCD II were significantly higher in the IIb subgroup. Although other MRI stigmata may contribute to the diagnosis, the only significant correlation was between the transmantle sign and FCD IIb. (orig.)

  20. Two Ramond-Ramond corrections to type II supergravity via field-theory amplitude

    Energy Technology Data Exchange (ETDEWEB)

    Bakhtiarizadeh, Hamid R. [Sirjan University of Technology, Department of Physics, Sirjan (Iran, Islamic Republic of)

    2017-12-15

    Motivated by the standard form of the string-theory amplitude, we calculate the field-theory amplitude to complete the higher-derivative terms in type II supergravity theories in their conventional form. We derive explicitly the O(α{sup '3}) interactions for the RR (Ramond-Ramond) fields with graviton, B-field and dilaton in the low-energy effective action of type II superstrings. We check our results by comparison with previous work that has been done by the other methods, and we find exact agreement. (orig.)

  1. Seven-branes and instantons in type IIB supergravity

    NARCIS (Netherlands)

    Hartong, Jelle

    2008-01-01

    F-theory provides a means to study the type IIB string theory in the non-perturbative regime where the complex coupling is of order unity. This should be contrasted with the perturbative regime where the string coupling is small. F-theory will be used in this thesis to argue for the existence of

  2. On running couplings in gauge theories from type-IIB supergravity

    CERN Document Server

    Kehagias, A A

    1999-01-01

    We construct an explicit solution of type-IIB supergravity describing the strong coupling regime of a non-supersymmetric gauge theory. The latter has a running coupling with an ultraviolet stable fixed point corresponding to the N=4 SU(N) super-Yang-Mills theory at large N. The running coupling has a power law behaviour, argued to be universal, that is consistent with holography. Around the critical point, our solution defines an asymptotic expansion for the gauge coupling beta-function. We also calculate the first correction to the Coulombic quark-antiquark potential.

  3. Precision holography for N={2}^{\\ast } on S 4 from type IIB supergravity

    Science.gov (United States)

    Bobev, Nikolay; Gautason, Friðrik Freyr; van Muiden, Jesse

    2018-04-01

    We find a new supersymmetric solution of type IIB supergravity which is holographically dual to the planar limit of the four-dimensional N={2}^{\\ast } supersymmetric Yang-Mills theory on S 4. We study a probe fundamental string in this background which is dual to a supersymmetric Wilson loop in the N={2}^{\\ast } theory. Using holography we calculate the expectation value of this line operator to leading order in the 't Hooft coupling. The result is a non-trivial function of the mass parameter of the N={2}^{\\ast } theory that precisely matches the result from supersymmetric localization.

  4. Non-perturbative scalar potential inspired by type IIA strings on rigid CY

    Energy Technology Data Exchange (ETDEWEB)

    Alexandrov, Sergei [Laboratoire Charles Coulomb (L2C), UMR 5221, CNRS-Université de Montpellier,F-34095, Montpellier (France); Ketov, Sergei V. [Department of Physics, Tokyo Metropolitan University,1-1 Minami-ohsawa, Hachioji-shi, Tokyo 192-0397 (Japan); Kavli Institute for the Physics and Mathematics of the Universe (IPMU), The University of Tokyo,Chiba 277-8568 (Japan); Institute of Physics and Technology, Tomsk Polytechnic University,30 Lenin Ave., Tomsk 634050 (Russian Federation); Wakimoto, Yuki [Department of Physics, Tokyo Metropolitan University,1-1 Minami-ohsawa, Hachioji-shi, Tokyo 192-0397 (Japan)

    2016-11-10

    Motivated by a class of flux compactifications of type IIA strings on rigid Calabi-Yau manifolds, preserving N=2 local supersymmetry in four dimensions, we derive a non-perturbative potential of all scalar fields from the exact D-instanton corrected metric on the hypermultiplet moduli space. Applying this potential to moduli stabilization, we find a discrete set of exact vacua for axions. At these critical points, the stability problem is decoupled into two subspaces spanned by the axions and the other fields (dilaton and Kähler moduli), respectively. Whereas the stability of the axions is easily achieved, numerical analysis shows instabilities in the second subspace.

  5. Type IIA photosensitivity and formation of pores in optical fibers under intense ultraviolet irradiation

    International Nuclear Information System (INIS)

    Kukushkin, S. A.; Shlyagin, M. G.; Swart, P. L.; Chtcherbakov, A. A.; Osipov, A. V.

    2007-01-01

    Formation of the type IIA Bragg gratings in germanosilicate optical fibers is studied. We report the observation of such a type of gratings in the standard single-mode fiber (Corning SMF-28) under different experimental conditions. A mechanism for the type IIA photosensitivity in optical fibers is proposed which is based on nucleation and evolution of pores from vacancy-type defects in fiber areas where a high level of mechanical stress is induced under intense ultraviolet (UV) light. Evolution of fiber core temperature under influence of a single 20 ns light pulse from a KrF excimer laser was measured and compared with theoretical calculations. It was shown that transient thermoinduced stress in the fiber core can achieve a level sufficient for effective nucleation of pores. A theory describing formation of pores in optical fibers has been developed and was used to estimate the pore nucleation rate, concentration, and other parameters of pore evolution for different levels of UV fluence and fiber core stress

  6. The N=1 effective actions of D-branes in Type IIA and IIB orientifolds

    International Nuclear Information System (INIS)

    Grimm, Thomas W.; Vieira Lopes, Daniel

    2012-01-01

    We discuss the four-dimensional N=1 effective actions of single space-time filling Dp-branes in general Type IIA and Type IIB Calabi-Yau orientifold compactifications. The effective actions depend on an infinite number of normal deformations and gauge connection modes. For D6-branes the N=1 Kähler potential, the gauge-coupling function, the superpotential and the D-terms are determined as functions of these fields. They can be expressed as integrals over chains which end on the D-brane cycle and a reference cycle. The infinite deformation space will reduce to a finite dimensional moduli space of special Lagrangian submanifolds upon imposing F- and D-term supersymmetry conditions. We show that the Type IIA moduli space geometry is captured by three real functionals encoding the deformations of special Lagrangian submanifolds, holomorphic three-forms and Kähler two-forms of Calabi-Yau manifolds. These elegantly combine in the N=1 Kähler potential, which reduces after applying mirror symmetry to the results previously determined for space-time filling D3-, D5- and D7-branes. We also propose general chain integral expressions for the Kähler potentials of Type IIB D-branes.

  7. BOOK REVIEW: Supergravity Supergravity

    Science.gov (United States)

    Gregory, Ruth

    2013-02-01

    Supergravity is an essential ingredient in so many areas of ultra high energy physics, yet it is rarely taught systematically, even at the graduate level. Students most often have to learn along with applying, and must use the now classic older texts. For such core material, it is surprising that there are so few good texts on the subject. It is not necessarily that supergravity is so much more conceptually complex, rather that it is technical and therefore easy for a text to become dry, dense and rather indigestible. This book, written by two experts in the field, is therefore a breath of fresh air. It not only represents a comprehensive modern overview of the subject, but achieves this with clarity, accessibility, and even humour! To paraphrase the authors, if you are not impressed by this book, you should put it down and watch television instead. It starts by reviewing, or overviewing, aspects of field theory, basic supersymmetry and gravity that will be needed for the rest of the book. This first third or so of the book is very condensed, and will not be easy to follow for those who have not encountered the material before. However, the authors acknowledge this and give plenty of suggestions for more pedagogical texts in the relevant areas, thus it does not feel overly brief. The middle section deals with the construction of supergravity, starting with basic N = 1 supergravity in 4 and 11 dimensions and gradually extending the discussion to include matter multiplets. This part of the book systematically builds up understanding and construction of models, before moving on to superconformal methods. The purpose is not to cover all supergravity theories, but to focus on a few examples in detail, and to give sufficient expertise and information for the reader to be able to deal with any other models they might need. The final part of the book deals with applications, and includes two chapters on applications in adS/CFT, which will be of most interest to new

  8. Hearing aid fitting for visual and hearing impaired patients with Usher syndrome type IIa.

    Science.gov (United States)

    Hartel, B P; Agterberg, M J H; Snik, A F; Kunst, H P M; van Opstal, A J; Bosman, A J; Pennings, R J E

    2017-08-01

    Usher syndrome is the leading cause of hereditary deaf-blindness. Most patients with Usher syndrome type IIa start using hearing aids from a young age. A serious complaint refers to interference between sound localisation abilities and adaptive sound processing (compression), as present in today's hearing aids. The aim of this study was to investigate the effect of advanced signal processing on binaural hearing, including sound localisation. In this prospective study, patients were fitted with hearing aids with a nonlinear (compression) and linear amplification programs. Data logging was used to objectively evaluate the use of either program. Performance was evaluated with a speech-in-noise test, a sound localisation test and two questionnaires focussing on self-reported benefit. Data logging confirmed that the reported use of hearing aids was high. The linear program was used significantly more often (average use: 77%) than the nonlinear program (average use: 17%). The results for speech intelligibility in noise and sound localisation did not show a significant difference between type of amplification. However, the self-reported outcomes showed higher scores on 'ease of communication' and overall benefit, and significant lower scores on disability for the new hearing aids when compared to their previous hearing aids with compression amplification. Patients with Usher syndrome type IIa prefer a linear amplification over nonlinear amplification when fitted with novel hearing aids. Apart from a significantly higher logged use, no difference in speech in noise and sound localisation was observed between linear and nonlinear amplification with the currently used tests. Further research is needed to evaluate the reasons behind the preference for the linear settings. © 2016 The Authors. Clinical Otolaryngology Published by John Wiley & Sons Ltd.

  9. More supersymmetric standardlike models from intersecting D6-branes on type IIA orientifolds

    International Nuclear Information System (INIS)

    Cvetic, Mirjam; Papadimitriou, Ioannis

    2003-01-01

    We present new classes of supersymmetric standardlike models from a type IIA T 6 /(Z 2 xZ 2 ) orientifold with intersecting D6-branes. D6-branes can wrap general supersymmetric three-cycles of T 6 =T 2 xT 2 xT 2 , and any T 2 is allowed to be tilted. The models still suffer from additional exotics; however, we obtain solutions with fewer Higgs doublets, as well as models with all three families of left-handed quarks and leptons arising from the same intersecting sector, and examples of a genuine left-right symmetric model with three copies of left-handed and right-handed families of quarks and leptons

  10. Supergravity theories

    International Nuclear Information System (INIS)

    Uehara, S.

    1985-01-01

    Of all supergravity theories, the maximal, i.e., N = 8 in 4-dimension or N = 1 in 11-dimension, theory should perform the unification since it owns the highest degree of symmetry. As to the N = 1 in d = 11 theory, it has been investigated how to compactify to the d = 4 theories. From the phenomenological point of view, local SUSY GUTs, i.e., N = 1 SUSY GUTs with soft breaking terms, have been studied from various angles. The structures of extended supergravity theories are less understood than those of N = 1 supergravity theories, and matter couplings in N = 2 extended supergravity theories are under investigation. The harmonic superspace was recently proposed which may be useful to investigate the quantum effects of extended supersymmetry and supergravity theories. As to the so-called Kaluza-Klein supergravity, there is another possibility. (Mori, K.)

  11. On (orientifold of) type IIA on a compact Calabi-Yau

    International Nuclear Information System (INIS)

    Misra, A.

    2004-01-01

    We study the gauged sigma model and its mirror Landau-Ginsburg model corresponding to type IIA on the Fermat degree-24 hypersurface in WCP 4 [1,1,2,8,12] (whose blow-up gives the smooth CY 3 (3,243)) away from the orbifold singularities, and its orientifold by a freely-acting antiholomorphic involution. We derive the Picard-Fuchs equation obeyed a period integral of a parent N=2 type IIA theory. We obtain the Meijer's basis of solutions to the equation in the large and small complex structure limits (on the mirror Landau-Ginsburg side) of the abovementioned Calabi-Yau, and make some remarks about the monodromy properties associated at the same and another MATHEMATICAlly interesting point. Based on a recently shown N=1 four-dimensional triality between Heterotic on the self-mirror Calabi-Yau CY 3 (11,11), M theory on CY 3 (3,243) x S 1 /(Z 2 ) and F-theory on an elliptically fibered CY 4 with the base given by CP 1 x Enriques surface, we first give a heuristic argument that there can be no superpotential generated in the orientifold of of CY 3 (3,243), and then explicitly verify the same using a mirror symmetry formulation for the abovementioned hypersurface away from its orbifold singularities. We then discuss briefly the sigma model and the mirror Landau-Ginsburg model corresponding to the resolved Calabi-Yau as well. (Abstract Copyright [2004], Wiley Periodicals, Inc.)

  12. HPHT growth and x-ray characterization of high-quality type IIa diamond.

    Science.gov (United States)

    Burns, R C; Chumakov, A I; Connell, S H; Dube, D; Godfried, H P; Hansen, J O; Härtwig, J; Hoszowska, J; Masiello, F; Mkhonza, L; Rebak, M; Rommevaux, A; Setshedi, R; Van Vaerenbergh, P

    2009-09-09

    The trend in synchrotron radiation (x-rays) is towards higher brilliance. This may lead to a very high power density, of the order of hundreds of watts per square millimetre at the x-ray optical elements. These elements are, typically, windows, polarizers, filters and monochromators. The preferred material for Bragg diffracting optical elements at present is silicon, which can be grown to a very high crystal perfection and workable size as well as rather easily processed to the required surface quality. This allows x-ray optical elements to be built with a sufficient degree of lattice perfection and crystal processing that they may preserve transversal coherence in the x-ray beam. This is important for the new techniques which include phase-sensitive imaging experiments like holo-tomography, x-ray photon correlation spectroscopy, coherent diffraction imaging and nanofocusing. Diamond has a lower absorption coefficient than silicon, a better thermal conductivity and lower thermal expansion coefficient which would make it the preferred material if the crystal perfection (bulk and surface) could be improved. Synthetic HPHT-grown (high pressure, high temperature) type Ib material can readily be produced in the necessary sizes of 4-8 mm square and with a nitrogen content of typically a few hundred parts per million. This material has applications in the less demanding roles such as phase plates: however, in a coherence-preserving beamline, where all elements must be of the same high quality, its quality is far from sufficient. Advances in HPHT synthesis methods have allowed the growth of type IIa diamond crystals of the same size as type Ib, but with substantially lower nitrogen content. Characterization of this high purity type IIa material has been carried out with the result that the crystalline (bulk) perfection of some of the HPHT-grown materials is approaching the quality required for the more demanding applications such as imaging applications and imaging

  13. Rotating D0-branes and consistent truncations of supergravity

    International Nuclear Information System (INIS)

    Anabalón, Andrés; Ortiz, Thomas; Samtleben, Henning

    2013-01-01

    The fluctuations around the D0-brane near-horizon geometry are described by two-dimensional SO(9) gauged maximal supergravity. We work out the U(1) 4 truncation of this theory whose scalar sector consists of five dilaton and four axion fields. We construct the full non-linear Kaluza–Klein ansatz for the embedding of the dilaton sector into type IIA supergravity. This yields a consistent truncation around a geometry which is the warped product of a two-dimensional domain wall and the sphere S 8 . As an application, we consider the solutions corresponding to rotating D0-branes which in the near-horizon limit approach AdS 2 ×M 8 geometries, and discuss their thermodynamical properties. More generally, we study the appearance of such solutions in the presence of non-vanishing axion fields

  14. Rotating D0-branes and consistent truncations of supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Anabalón, Andrés [Departamento de Ciencias, Facultad de Artes Liberales, Facultad de Ingeniería y Ciencias, Universidad Adolfo Ibáñez, Av. Padre Hurtado 750, Viña del Mar (Chile); Université de Lyon, Laboratoire de Physique, UMR 5672, CNRS École Normale Supérieure de Lyon 46, allée d' Italie, F-69364 Lyon cedex 07 (France); Ortiz, Thomas; Samtleben, Henning [Université de Lyon, Laboratoire de Physique, UMR 5672, CNRS École Normale Supérieure de Lyon 46, allée d' Italie, F-69364 Lyon cedex 07 (France)

    2013-12-18

    The fluctuations around the D0-brane near-horizon geometry are described by two-dimensional SO(9) gauged maximal supergravity. We work out the U(1){sup 4} truncation of this theory whose scalar sector consists of five dilaton and four axion fields. We construct the full non-linear Kaluza–Klein ansatz for the embedding of the dilaton sector into type IIA supergravity. This yields a consistent truncation around a geometry which is the warped product of a two-dimensional domain wall and the sphere S{sup 8}. As an application, we consider the solutions corresponding to rotating D0-branes which in the near-horizon limit approach AdS{sub 2}×M{sub 8} geometries, and discuss their thermodynamical properties. More generally, we study the appearance of such solutions in the presence of non-vanishing axion fields.

  15. Computing the scalar field couplings in 6D supergravity

    Science.gov (United States)

    Saidi, El Hassan

    2008-11-01

    Using non-chiral supersymmetry in 6D space-time, we compute the explicit expression of the metric the scalar manifold SO(1,1)×{SO(4,20)}/{SO(4)×SO(20)} of the ten-dimensional type IIA superstring on generic K3. We consider as well the scalar field self-couplings in the general case where the non-chiral 6D supergravity multiplet is coupled to generic n vector supermultiplets with moduli space SO(1,1)×{SO(4,n)}/{SO(4)×SO(n)}. We also work out a dictionary giving a correspondence between hyper-Kähler geometry and the Kähler geometry of the Coulomb branch of 10D type IIA on Calabi-Yau threefolds. Others features are also discussed.

  16. Forced fluid dynamics from blackfolds in general supergravity backgrounds

    Energy Technology Data Exchange (ETDEWEB)

    Armas, Jay [Physique Théorique et Mathématique,Université Libre de Bruxelles and International Solvay Institutes,ULB-Campus Plaine CP231, B-1050 Brussels (Belgium); Gath, Jakob [Centre de Physique Théorique, École Polytechnique,CNRS UMR 7644, Université Paris-Saclay,F-91128 Palaiseau (France); Niarchos, Vasilis [Crete Center for Theoretical Physics, Institute of Theoretical and Computational Physics,Crete Center for Quantum Complexity and Nanotechnology,Department of Physics, University of Crete,Heraklion, 71303 (Greece); Obers, Niels A.; Pedersen, Andreas Vigand [The Niels Bohr Institute, Copenhagen University,Blegdamsvej 17, DK-2100 Copenhagen Ø (Denmark)

    2016-10-27

    We present a general treatment of the leading order dynamics of the collective modes of charged dilatonic p-brane solutions of (super)gravity theories in arbitrary backgrounds. To this end we employ the general strategy of the blackfold approach which is based on a long-wavelength derivative expansion around an exact or approximate solution of the (super)gravity equations of motion. The resulting collective mode equations are formulated as forced hydrodynamic equations on dynamically embedded hypersurfaces. We derive them in full generality (including all possible asymptotic fluxes and dilaton profiles) in a far-zone analysis of the (super)gravity equations and in representative examples in a near-zone analysis. An independent treatment based on the study of external couplings in hydrostatic partition functions is also presented. Special emphasis is given to the forced collective mode equations that arise in type IIA/B and eleven-dimensional supergravities, where besides the standard Lorentz force couplings our analysis reveals additional couplings to the background, including terms that arise from Chern-Simons interactions. We also present a general overview of the blackfold approach and some of the key conceptual issues that arise when applied to arbitrary backgrounds.

  17. Three-forms in supergravity and flux compactifications

    Energy Technology Data Exchange (ETDEWEB)

    Farakos, Fotis; Lanza, Stefano; Martucci, Luca; Sorokin, Dmitri [Univ. degli Studi di Padova (Italy). Dipt. di Fisica e Astronomia ' ' Galileo Galilei' ' ; I.N.F.N., Sezione di Padova (Italy)

    2017-09-15

    We present a duality procedure that relates conventional four-dimensional matter-coupled N = 1 supergravities to dual formulations in which auxiliary fields are replaced by field strengths of gauge three-forms. The duality promotes specific coupling constants appearing in the superpotential to vacuum expectation values of the field strengths. We then apply this general duality to type IIA string compactifications on Calabi-Yau orientifolds with RR fluxes. This gives a new supersymmetric formulation of the corresponding effective four-dimensional theories which includes gauge three-forms. (orig.)

  18. Expressivity of hearing loss in cases with Usher syndrome type IIA.

    Science.gov (United States)

    Sadeghi, André M; Cohn, Edward S; Kimberling, William J; Halvarsson, Glenn; Möller, Claes

    2013-12-01

    The purpose of this study was to compare the genotype/phenotype relationship between siblings with identical USH2A pathologic mutations and the consequent audiologic phenotypes, in particular degree of hearing loss (HL). Decade audiograms were also compared among two groups of affected subjects with different mutations of USH2A. DNA samples from patients with Usher syndrome type II were analysed. The audiological features of patients and affected siblings with USH2A mutations were also examined to identify genotype-phenotype correlations. Genetic and audiometric examinations were performed in 18 subjects from nine families with Usher syndrome type IIA. Three different USH2A mutations were identified in the affected subjects. Both similarities and differences of the auditory phenotype were seen in families with several affected siblings. A variable degree of hearing loss, ranging from mild to profound, was observed among affected subjects. No significant differences in hearing thresholds were found the group of affected subjects with different pathological mutations. Our results indicate that mutations in the USH2A gene and the resulting phenotype are probably modulated by other variables, such as modifying genes, epigenetics or environmental factors which may be of importance for better understanding the etiology of Usher syndrome.

  19. Cochlear Implantation in Patients With Usher Syndrome Type IIa Increases Performance and Quality of Life.

    Science.gov (United States)

    Hartel, Bas P; van Nierop, Josephine W I; Huinck, Wendy J; Rotteveel, Liselotte J C; Mylanus, Emmanuel A M; Snik, Ad F; Kunst, Henricus P M; Pennings, Ronald J E

    2017-07-01

    Usher syndrome type IIa (USH2a) is characterized by congenital moderate to severe hearing impairment and retinitis pigmentosa. Hearing rehabilitation starts in early childhood with the application of hearing aids. In some patients with USH2a, severe progression of hearing impairment leads to insufficient speech intelligibility with hearing aids and issues with adequate communication and safety. Cochlear implantation (CI) is the next step in rehabilitation of such patients. This study evaluates the performance and benefit of CI in patients with USH2a. Retrospective case-control study to evaluate the performance and benefit of CI in 16 postlingually deaf adults (eight patients with USH2a and eight matched controls). Performance and benefit were evaluated by a speech intelligibility test and three quality-of-life questionnaires. Patients with USH2a with a mean age of 59 years at implantation exhibited good performance after CI. The phoneme scores improved significantly from 41 to 87% in patients with USH2a (p = 0.02) and from 30 to 86% in the control group (p = 0.001). The results of the questionnaire survey demonstrated a clear benefit from CI. There were no differences in performance or benefit between patients with USH2a and control patients before and after CI. CI increases speech intelligibility and improves quality of life in patients with USH2a.

  20. Development and clinical application in arthritis of a new immunoassay for serum type IIA procollagen NH2 propeptide.

    Science.gov (United States)

    Rousseau, Jean-Charles; Sandell, Linda J; Delmas, Pierre D; Garnero, Patrick

    2004-01-01

    Type II collagen, the most abundant protein of cartilage matrix, is synthesized as a procollagen molecule including the N-(PIINP) and C-(PIICP) propeptides at each end. Type II procollagen is produced in two forms as the result of alternative RNA splicing. One form (IIA) includes and the other form (IIB) excludes a 69-amino acid cysteine-rich globular domain encoded by exon 2 in PIINP. During the process of synthesis, these N-propeptides are removed by specific proteases and released in the circulation, and their levels are believed to reflect type II collagen synthesis. In this chapter we describe the development of a specific enzyme-linked immunosorbent assay (ELISA) for the measurement of the IIA form of PIINP (PIIANP) in serum based on a polyclonal antibody raised against recombinant human exon 2 fusion protein of type II procollagen. We show that this ELISA is highly specific for circulating PIIANP and has adequate technical precision. In patients with knee osteoarthritis and rheumatoid arthritis, serum PIIANP was decreased by 53% (p type IIA collagen synthesis is altered in these arthritic diseases. The measurement of serum PIIANP may be useful for the clinical investigation of patients with joint diseases.

  1. Euclidean supergravity

    Science.gov (United States)

    de Wit, Bernard; Reys, Valentin

    2017-12-01

    Supergravity with eight supercharges in a four-dimensional Euclidean space is constructed at the full non-linear level by performing an off-shell time-like reduction of five-dimensional supergravity. The resulting four-dimensional theory is realized off-shell with the Weyl, vector and tensor supermultiplets and a corresponding multiplet calculus. Hypermultiplets are included as well, but they are themselves only realized with on-shell supersymmetry. We also briefly discuss the non-linear supermultiplet. The off-shell reduction leads to a full understanding of the Euclidean theory. A complete multiplet calculus is presented along the lines of the Minkowskian theory. Unlike in Minkowski space, chiral and anti-chiral multiplets are real and supersymmetric actions are generally unbounded from below. Precisely as in the Minkowski case, where one has different formulations of Poincaré supergravity upon introducing different compensating supermultiplets, one can also obtain different versions of Euclidean supergravity.

  2. Supergravity Unification

    CERN Document Server

    Chamseddine, A H; Nath, Pran; Chamseddine, Ali H.; Nath, Pran

    2001-01-01

    A review is given of the historical developments of 1982 that lead to the supergravity unified model (SUGRA)with gravity mediated breaking of supersymmetry. Further developments and applications of the model in the period 1982-85 are also discussed. The supergravity unified model and its minimal version (mSUGRA) are currently among the leading candidates for physics beyond the Standard Model. A brief note on the developments from the present vantage point is included.

  3. Properties of Nilpotent Supergravity

    CERN Document Server

    Dudas, E.; Kehagias, A.; Sagnotti, A.

    2015-09-30

    We construct Supergravity models where the goldstino multiplet has a gravitational origin, being dual to the chiral curvature superfield. Supersymmetry is nonlinearly realized due to a nilpotent constraint, while the goldstino arises from $\\gamma$-traces of the gauge-invariant gravitino field strength. After duality transformations one recovers, as expected, the standard Volkov-Akulov Lagrangian coupled to Supergravity, but the gravitational origin of the goldstino multiplet restricts the available types of matter couplings. We also construct explicitly some inflationary models of this type, which contain both the inflaton and the nilpotent superfield.

  4. Properties of nilpotent supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Dudas, E. [Centre de Physique Théorique, École Polytéchnique,F-91128 Palaiseau (France); Deutsches Elektronen-Synchrotron DESY,22607 Hamburg (Germany); Ferrara, S. [Th-Ph Department, CERN,CH-1211 Geneva 23 (Switzerland); INFN - Laboratori Nazionali di Frascati,Via Enrico Fermi 40, 00044 Frascati (Italy); Department of Physics and Astronomy, University of California,Los Angeles, CA 90095-1547 (United States); Kehagias, A. [Th-Ph Department, CERN,CH-1211 Geneva 23 (Switzerland); Physics Division, National Technical University of Athens,15780 Zografou, Athens (Greece); Sagnotti, A. [Th-Ph Department, CERN,CH-1211 Geneva 23 (Switzerland); Scuola Normale Superiore and INFN,Piazza dei Cavalieri 7, 56126 Pisa (Italy)

    2015-09-30

    We construct supergravity models where the goldstino multiplet has a gravitational origin, being dual to the chiral curvature superfield. Supersymmetry is nonlinearly realized due to a nilpotent constraint, while the goldstino arises from γ-traces of the gauge-invariant gravitino field strength. After duality transformations one recovers, as expected, the standard Volkov-Akulov Lagrangian coupled to Supergravity, but the gravitational origin of the goldstino multiplet restricts the available types of matter couplings. We also construct explicitly some inflationary models of this type, which contain both the inflaton and the nilpotent superfield.

  5. Supergravity solitons

    International Nuclear Information System (INIS)

    Aichelburg, P.C.; Embacher, F.

    1987-01-01

    In previous work solitons of N = 2 supergravity were described as test particles in an external supergravity field. In the present paper we derive the effective interaction of two solitons by inserting a classical soliton configuration for the background into the Lagrangian and apply a slow-motion and large-distance approximation. We obtain the interaction potential to lowest order that incorporates the effect of the supercharge. The resulting classical system is quantized and, as a final step, an effective quantum field theory is formulated. (Author)

  6. Visual Prognosis in USH2A-Associated Retinitis Pigmentosa Is Worse for Patients with Usher Syndrome Type IIa Than for Those with Nonsyndromic Retinitis Pigmentosa.

    Science.gov (United States)

    Pierrache, Laurence H M; Hartel, Bas P; van Wijk, Erwin; Meester-Smoor, Magda A; Cremers, Frans P M; de Baere, Elfride; de Zaeytijd, Julie; van Schooneveld, Mary J; Cremers, Cor W R J; Dagnelie, Gislin; Hoyng, Carel B; Bergen, Arthur A; Leroy, Bart P; Pennings, Ronald J E; van den Born, L Ingeborgh; Klaver, Caroline C W

    2016-05-01

    USH2A mutations are an important cause of retinitis pigmentosa (RP) with or without congenital sensorineural hearing impairment. We studied genotype-phenotype correlations and compared visual prognosis in Usher syndrome type IIa and nonsyndromic RP. Clinic-based, longitudinal, multicenter study. Consecutive patients with Usher syndrome type IIa (n = 152) and nonsyndromic RP (n = 73) resulting from USH2A mutations from ophthalmogenetic clinics in the Netherlands and Belgium. Data on clinical characteristics, visual acuity, visual field measurements, retinal imaging, and electrophysiologic features were extracted from medical charts over a mean follow-up of 9 years. Cumulative lifetime risks of low vision and blindness were estimated using Kaplan-Meier survival analysis. Low vision and blindness. Participant groups had similar distributions of gender (48% vs. 45% males in Usher syndrome type IIa vs. nonsydromic RP; P = 0.8), ethnicity (97% vs. 99% European; P = 0.3), and median follow-up time (6.5 years vs. 3 years; P = 0.3). Usher syndrome type IIa patients demonstrated symptoms at a younger age (median age, 15 years vs. 25 years; P syndromic phenotype, whereas other combinations were present in both groups. We found novel variants in Usher syndrome type IIa (25%) and nonsyndromic RP (19%): 29 missense mutations, 10 indels, 14 nonsense mutations, 9 frameshift mutations, and 5 splice-site mutations. Most patients with USH2A-associated RP have severe visual impairment by age 50. However, those with Usher syndrome type IIa have an earlier decline of visual function and a higher cumulative risk of visual impairment than those without nonsyndromic RP. Complete loss of function of the USH2A protein predisposes to Usher syndrome type IIa, but remnant protein function can lead to RP with or without hearing loss. Copyright © 2016 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  7. Influence of fast and slow alkali myosin light chain isoforms on the kinetics of stretch-induced force transients of fast-twitch type IIA fibres of rat.

    Science.gov (United States)

    Andruchov, Oleg; Galler, Stefan

    2008-03-01

    This study contributes to understand the physiological role of slow myosin light chain isoforms in fast-twitch type IIA fibres of skeletal muscle. These isoforms are often attached to the myosin necks of rat type IIA fibres, whereby the slow alkali myosin light chain isoform MLC1s is much more frequent and abundant than the slow regulatory myosin light chain isoform MLC2s. In the present study, single-skinned rat type IIA fibres were maximally Ca(2+) activated and subjected to stepwise stretches for causing a perturbation of myosin head pulling cycles. From the time course of the resulting force transients, myosin head kinetics was deduced. Fibres containing MLC1s exhibited slower kinetics independently of the presence or absence of MLC2s. At the maximal MLC1s concentration of about 75%, the slowing was about 40%. The slowing effect of MLC1s is possibly due to differences in the myosin heavy chain binding sites of the fast and slow alkali MLC isoforms, which changes the rigidity of the myosin neck. Compared with the impact of myosin heavy chain isoforms in various fast-twitch fibre types, the influence of MLC1s on myosin head kinetics of type IIA fibres is much smaller. In conclusion, the physiological role of fast and slow MLC isoforms in type IIA fibres is a fine-tuning of the myosin head kinetics.

  8. Consistent classical supergravity theories

    International Nuclear Information System (INIS)

    Muller, M.

    1989-01-01

    This book offers a presentation of both conformal and Poincare supergravity. The consistent four-dimensional supergravity theories are classified. The formulae needed for further modelling are included

  9. Supergravity solitons

    International Nuclear Information System (INIS)

    Aichelburg, P.C.; Embacher, F.

    1987-01-01

    The motion of a soliton in a supergravity background configuration is studied. The dynamics of the soliton is desribed by a trajectory in curved N = 2 superspace. For the proposed Langrangian the moments, the constraints and the generators of local supertranslations are displayed. An additional local gauge symmetry is exhibited. Special emphasis is laid on the classical equations of motion. These turn out to be a supersymmetric generalization of Papapetrou's equation of motion for a spinning particle in a gravitational field. (Author)

  10. Matter couplings in supergravity theories

    International Nuclear Information System (INIS)

    Bagger, J.A.

    1983-01-01

    The N = 1 supersymmetric nonlinear sigma model is coupled to supergravity. The results are expressed in the language of Kahler geometry. Topological considerations constrain the scalar fields to lie on a Kahler manifold of restricted type, or a Hodge manifold. For topologically nontrivial manifolds, this leads to the quantization of Newton's constant in terms of the scalar self-coupling. The isometries of the N = 1 model are gauged. This gives a geometrical picture of what might be called the gauge invariant supersymmetric nonlinear sigma model. It also provides a new interpretation of the Fayet-Iliopoulos D-term. The gauge invariant supersymmetric nonlinear sigma model is coupled to N = 1 supergravity. This leads to a deeper understanding of the connections between supergravity, R-invariance and the Fayet-Iliopoulos D-term. It also provides a foundation for phenomenological studies of supergravity theories. Finally, the N = 2 supersymmetric nonlinear sigma model is coupled to supergravity. The scalar fields are found to lie on a negatively curved quaternionic manifold. This implies that matter self-couplings that are allowed in N = 2 supersymmetry are forbidden in N = 2 supergravity, and vice versa

  11. One-point functions of non-SUSY operators at arbitrary genus in a matrix model for type IIA superstrings

    International Nuclear Information System (INIS)

    Kuroki, Tsunehide; Sugino, Fumihiko

    2017-01-01

    In the previous paper, the authors pointed out correspondence between a supersymmetric double-well matrix model and two-dimensional type IIA superstring theory on a Ramond–Ramond background from the viewpoint of symmetry and spectrum. This was confirmed by agreement between planar correlation functions in the matrix model and tree-level amplitudes in the superstring theory. In order to investigate the correspondence further, in this paper we compute correlation functions to all order of genus expansion in the double scaling limit of the matrix model. One-point functions of operators protected by supersymmetry terminate at some finite order, whereas those of unprotected operators yield non-Borel summable series. The behavior of the latter is characteristic in string perturbation series, providing further evidence that the matrix model describes a string theory. Moreover, instanton corrections to the planar one-point functions are also computed, and universal logarithmic scaling behavior is found for non-supersymmetric operators.

  12. One-point functions of non-SUSY operators at arbitrary genus in a matrix model for type IIA superstrings

    Energy Technology Data Exchange (ETDEWEB)

    Kuroki, Tsunehide, E-mail: kuroki@dg.kagawa-nct.ac.jp [General Eduction, National Institute of Technology, Kagawa College, 551 Kohda, Takuma-cho, Mitoyo, Kagawa 769-1192 (Japan); Sugino, Fumihiko, E-mail: fusugino@gmail.com [Okayama Institute for Quantum Physics, Furugyocho 1-7-36, Naka-ku, Okayama 703-8278 (Japan)

    2017-06-15

    In the previous paper, the authors pointed out correspondence between a supersymmetric double-well matrix model and two-dimensional type IIA superstring theory on a Ramond–Ramond background from the viewpoint of symmetry and spectrum. This was confirmed by agreement between planar correlation functions in the matrix model and tree-level amplitudes in the superstring theory. In order to investigate the correspondence further, in this paper we compute correlation functions to all order of genus expansion in the double scaling limit of the matrix model. One-point functions of operators protected by supersymmetry terminate at some finite order, whereas those of unprotected operators yield non-Borel summable series. The behavior of the latter is characteristic in string perturbation series, providing further evidence that the matrix model describes a string theory. Moreover, instanton corrections to the planar one-point functions are also computed, and universal logarithmic scaling behavior is found for non-supersymmetric operators.

  13. On matter couplings in N=1 supergravities

    International Nuclear Information System (INIS)

    Galperin, A.; Ogievskiy, V.; Sokatchev, E.

    1983-01-01

    A flexible version of N=1 supergravity is proposed. It contains 28+28 fields and is an extension of the new minimal supergravity version. Matter couplings in various N=1 supergravity versions are discussed. The chiral densities are constructed for non-minimal and flexible versions. Therefore these versions admit a general R-non-invariant matter coupling as the minimal supergravity does. A modified Fayet-Iliopoulos type mechanism is conjectured which apparently can work in the non-minimal and flexible versions without R-symmetry of the superpotential unlike the minimal and new minimal ones

  14. A combination of two truncating mutations in USH2A causes more severe and progressive hearing impairment in Usher syndrome type IIa

    NARCIS (Netherlands)

    Hartel, B.P.; Lofgren, M.; Huygen, P.L.; Guchelaar, I.; Lo, A.N.K.N.; Sadeghi, A.M.; van Wijk, E.; Tranebjaerg, L.; Kremer, H.; Kimberling, W.J.; Cremers, C.W.R.J.; Moller, C.; Pennings, R.J.

    2016-01-01

    OBJECTIVES: Usher syndrome is an inherited disorder that is characterized by hearing impairment (HI), retinitis pigmentosa, and in some cases vestibular dysfunction. Usher syndrome type IIa is caused by mutations in USH2A. HI in these patients is highly heterogeneous and the present study evaluates

  15. Visual Prognosis in USH2A-Associated Retinitis Pigmentosa Is Worse for Patients with Usher Syndrome Type IIa Than for Those with Nonsyndromic Retinitis Pigmentosa

    NARCIS (Netherlands)

    Pierrache, Laurence H. M.; Hartel, Bas P.; van Wijk, Erwin; Meester-Smoor, Magda A.; Cremers, Frans P. M.; de Baere, Elfride; de Zaeytijd, Julie; van Schooneveld, Mary J.; Cremers, Cor W. R. J.; Dagnelie, Gislin; Hoyng, Carel B.; Bergen, Arthur A.; Leroy, Bart P.; Pennings, Ronald J. E.; van den Born, L. Ingeborgh; Klaver, Caroline C. W.

    2016-01-01

    USH2A mutations are an important cause of retinitis pigmentosa (RP) with or without congenital sensorineural hearing impairment. We studied genotype-phenotype correlations and compared visual prognosis in Usher syndrome type IIa and nonsyndromic RP. Clinic-based, longitudinal, multicenter study.

  16. Visual Prognosis in USH2A-Associated Retinitis Pigmentosa Is Worse for Patients with Usher Syndrome Type IIa Than for Those with Nonsyndromic Retinitis Pigmentosa

    NARCIS (Netherlands)

    Pierrache, Laurence H M; Hartel, Bas P; van Wijk, Erwin; Meester-Smoor, Magda A; Cremers, Frans P M; de Baere, Elfride; de Zaeytijd, Julie; van Schooneveld, Mary J; Cremers, Cor W R J; Dagnelie, Gislin; Hoyng, Carel B; Bergen, Arthur A; Leroy, Bart P; Pennings, Ronald J E; van den Born, L Ingeborgh; Klaver, Caroline C W

    2016-01-01

    PURPOSE: USH2A mutations are an important cause of retinitis pigmentosa (RP) with or without congenital sensorineural hearing impairment. We studied genotype-phenotype correlations and compared visual prognosis in Usher syndrome type IIa and nonsyndromic RP. DESIGN: Clinic-based, longitudinal,

  17. Isolation and Characterization of Plantaricin Produced by Lactobacillus plantarum Strains (IIA-1A5, IIA-1B1, IIA-2B2

    Directory of Open Access Journals (Sweden)

    I. I. Arief

    2013-08-01

    Full Text Available Bacteriocins produced by Indonesian lactic acid bacteria Lactobacillus plantarum IIA-1A5, IIA-1B1, IIA-2B2 were purified and characterized. Plantaricin W gene had been successfully amplified from all strains. This amplicon showed the expected 200 bp size of plantaricin W gene. This bacteriocins purified from L. plantarum IIA-1A5, IIA-1B1, and IIA-2B2 were named plantaricin IIA-1A5, IIA-1B1, and IIA-2B2. Purification by cation exchange chromatography increased the purity (fold and activity of plantaricins. Purity of plantaricin IIA-1A5 was increased by 3.13 fold with specific activity 13.40 AU/mg. Plantaricin IIA-1B1 had 2.98 fold purity with specific activity 5.12 AU/mg, while purity of plantaricin IIA-2B2 was 1.37 fold with specific activity 7.70 AU/mg. All plantaricins could inhibit the growth of pathogenic bacteria, such as Escherichia coli, Salmonella typhimurium, Bacillus cereus, and Staphylococcus aureus. Plantaricins could be digested by trypsin. Stability of plantaricins at 80 oC for 30 min and at 121 oC for 15 min were affected by type of plantaricin and species of pathogenic bacteria. Generally, plantaricin IIA-1A5 was better as antimicrobial agent than plantaricin IIA-1B1 and plantaricin IIA-2B2.

  18. New supersymmetric AdS4 type II vacua

    International Nuclear Information System (INIS)

    Tsimpis, D.

    2010-01-01

    We review the supersymmetric AdS 4 x w M 6 backgrounds of type IIA/IIB supergravity constructed in[1]. In type IIA the supersymmetry is N=2, and the six-dimensional internal space is locally an S 2 bundle over a four-dimensional Kaehler-Einstein base; in IIB the internal space is the direct product of a circle and a five-dimensional squashed Sasaki-Einstein manifold. These backgrounds do not contain any sources, all fluxes (including the Romans mass in IIA) are generally non-zero, and the dilaton and warp factor are non-constant. The IIA solutions include the massive deformations of the IIA reduction of the eleven-dimensional AdS 4 x Y p,q solutions, and had been predicted to exist on the basis of the AdS 4 /CFT 3 correspondence. (Abstract Copyright [2010], Wiley Periodicals, Inc.)

  19. One-point functions of non-SUSY operators at arbitrary genus in a matrix model for type IIA superstrings

    Directory of Open Access Journals (Sweden)

    Tsunehide Kuroki

    2017-06-01

    Full Text Available In the previous paper, the authors pointed out correspondence between a supersymmetric double-well matrix model and two-dimensional type IIA superstring theory on a Ramond–Ramond background from the viewpoint of symmetry and spectrum. This was confirmed by agreement between planar correlation functions in the matrix model and tree-level amplitudes in the superstring theory. In order to investigate the correspondence further, in this paper we compute correlation functions to all order of genus expansion in the double scaling limit of the matrix model. One-point functions of operators protected by supersymmetry terminate at some finite order, whereas those of unprotected operators yield non-Borel summable series. The behavior of the latter is characteristic in string perturbation series, providing further evidence that the matrix model describes a string theory. Moreover, instanton corrections to the planar one-point functions are also computed, and universal logarithmic scaling behavior is found for non-supersymmetric operators.

  20. A combination of two truncating mutations in USH2A causes more severe and progressive hearing impairment in Usher syndrome type IIa

    DEFF Research Database (Denmark)

    Hartel, Bas P.; Lofgren, Maria; Huygen, Patrick L. M.

    2016-01-01

    Objectives Usher syndrome is an inherited disorder that is characterized by hearing impairment (HI), retinitis pigmentosa, and in some cases vestibular dysfunction. Usher syndrome type IIa is caused by mutations in USH2A. HI in these patients is highly heterogeneous and the present study evaluates...... the effects of different types of USH2A mutations on the audiometric phenotype. Data from two large centres of expertise on Usher Syndrome in the Netherlands and Sweden were combined in order to create a large combined sample of patients to identify possible genotype-phenotype correlations. Design...... A retrospective study on HI in 110 patients (65 Dutch and 45 Swedish) genetically diagnosed with Usher syndrome type IIa. We used methods especially designed for characterizing and testing differences in audiological phenotype between patient subgroups. These methods included Age Related Typical Audiograms (ARTA...

  1. Reappraisal of VAChT-Cre: Preference in slow motor neurons innervating type I or IIa muscle fibers.

    Science.gov (United States)

    Misawa, Hidemi; Inomata, Daijiro; Kikuchi, Miseri; Maruyama, Sae; Moriwaki, Yasuhiro; Okuda, Takashi; Nukina, Nobuyuki; Yamanaka, Tomoyuki

    2016-11-01

    VAChT-Cre.Fast and VAChT-Cre.Slow mice selectively express Cre recombinase in approximately one half of postnatal somatic motor neurons. The mouse lines have been used in various studies with selective genetic modifications in adult motor neurons. In the present study, we crossed VAChT-Cre lines with a reporter line, CAG-Syp/tdTomato, in which synaptophysin-tdTomato fusion proteins are efficiently sorted to axon terminals, making it possible to label both cell bodies and axon terminals of motor neurons. In the mice, Syp/tdTomato fluorescence preferentially co-localized with osteopontin, a recently discovered motor neuron marker for slow-twitch fatigue-resistant (S) and fast-twitch fatigue-resistant (FR) types. The fluorescence did not preferentially co-localize with matrix metalloproteinase-9, a marker for fast-twitch fatigable (FF) motor neurons. In the neuromuscular junctions, Syp/tdTomato fluorescence was detected mainly in motor nerve terminals that innervate type I or IIa muscle fibers. These results suggest that the VAChT-Cre lines are Cre-drivers that have selectivity in S and FR motor neurons. In order to avoid confusion, we have changed the mouse line names from VAChT-Cre.Fast and VAChT-Cre.Slow to VAChT-Cre.Early and VAChT-Cre.Late, respectively. The mouse lines will be useful tools to study slow-type motor neurons, in relation to physiology and pathology. © 2016 Wiley Periodicals, Inc.

  2. Introduction to supergravity

    International Nuclear Information System (INIS)

    Wit, B. de.

    1984-06-01

    These lectures aim at introducing supergravity in its most simple and direct form. After explaining the main features of graviton and gravitino fields the invariance of simple supergravity in d=4 dimension are proved. The complications for higher-dimensional supergravity are explained and d=11 supergravity is presented. The author discusses supersymmetry in anti-de Sitter space, which allows him to introduce the concept of isometries and Killing spinors and vectors. The breaking of supersymmetry (super-Brout-Englert-Higgs effect), off-shell aspects of supergravity and the superconformal multiplet calculus are dealt with. This is first done for gravity, but also for the structure of simple d=4 conformal supergravity. Finally, the coupling of scalar fields to N=1 and N=2 supergravity as an application of this formalism is discussed. (Auth.)

  3. Platelet half-life in patients with primary hyperlipoproteinemia type IIa, IIb, and IV according to Fredrickson with and without clinical signs of atherosclerosis

    Energy Technology Data Exchange (ETDEWEB)

    Jaeger, E; Sinzinger, H; Widhalm, K; Kaliman, J; Hoefer, R [Vienna Univ. (Austria). 2. Medizinische Klinik; Ludwig Boltzmann-Institut fuer Nuklearmedizin, Vienna (Austria); Vienna Univ. (Austria). Kinderklinik; Vienna Univ. (Austria). Kardiologische Klinik)

    1982-09-01

    It is generally accepted that platelet half-life is shortened in atherosclerotic vascular diseases. Concerning changes due to hyperlipoproteinemia (HLP), however, there exist only few data. Therefore, we examined the platelet-half life in 60 patients with recently discovered HLP type IIa, IIb and IV according to Fredrickson before treatment in comparison to 60 controls. 33 of the HLP-patients had no clinical symptoms of angiopathy. 27 patients suffered from peripheral vascular disease or from coronary heart disease as verified by angiography. The labelling of autologous platelets was performed with 100..mu..Ci of /sup 111/Indium-oxine-sulfate at 37/sup 0/C for 5 minutes. The mean labelling efficiency was 90%, the recovery after 2 hours about 70%. Serum lipoproteins were estimated by means of ultracentrifugation and polyanionprecipitation according to Lipid Research Clinic Methods. In the patients with HLP platelet half-life was significantly shortened in comparison to the control group (p < 0.01). These changes were most pronounced in patients with HLP-type IIa and with atherosclerotic lesions, respectively. In patients with HLP-type IIa a very close correlation could be demonstrated between platelet half-life and LDL-cholesterol (r = -0.72; p < 0.001) as well as total cholesterol (r = -0.73; p < 0.001). These data prove that in HLP in-vivo platelet function as measured by platelet survival is significantly influenced even before the occurrence of clinically relevant symptoms of atherosclerosis.

  4. Analysis of the type II-A CRISPR-Cas system of Streptococcus agalactiae reveals distinctive features according to genetic lineages

    Science.gov (United States)

    Lier, Clément; Baticle, Elodie; Horvath, Philippe; Haguenoer, Eve; Valentin, Anne-Sophie; Glaser, Philippe; Mereghetti, Laurent; Lanotte, Philippe

    2015-01-01

    CRISPR-Cas systems (clustered regularly interspaced short palindromic repeats/CRISPR-associated proteins) are found in 90% of archaea and about 40% of bacteria. In this original system, CRISPR arrays comprise short, almost unique sequences called spacers that are interspersed with conserved palindromic repeats. These systems play a role in adaptive immunity and participate to fight non-self DNA such as integrative and conjugative elements, plasmids, and phages. In Streptococcus agalactiae, a bacterium implicated in colonization and infections in humans since the 1960s, two CRISPR-Cas systems have been described. A type II-A system, characterized by proteins Cas9, Cas1, Cas2, and Csn2, is ubiquitous, and a type I–C system, with the Cas8c signature protein, is present in about 20% of the isolates. Unlike type I–C, which appears to be non-functional, type II-A appears fully functional. Here we studied type II-A CRISPR-cas loci from 126 human isolates of S. agalactiae belonging to different clonal complexes that represent the diversity of the species and that have been implicated in colonization or infection. The CRISPR-cas locus was analyzed both at spacer and repeat levels. Major distinctive features were identified according to the phylogenetic lineages previously defined by multilocus sequence typing, especially for the sequence type (ST) 17, which is considered hypervirulent. Among other idiosyncrasies, ST-17 shows a significantly lower number of spacers in comparison with other lineages. This characteristic could reflect the peculiar virulence or colonization specificities of this lineage. PMID:26124774

  5. Supergravity and matter

    International Nuclear Information System (INIS)

    Adamietz, P.; Binetruy, P.; Girardi, G.; Grimm, R.

    1992-07-01

    The properties of a linear multiplet in interaction with supergravity and matter are presented, with a special emphasis on the coupling of Chern-Simons forms, relevant for the problem of the chiral and conformal anomalies in relation with Kaehler transformations and the corresponding anomaly cancellations. The linear supermultiplet describes an antisymmetric tensor gauge field together with a dilaton and a Majorana spinor. In particular, these fields are found among the massless modes of superstring theories. The general properties of this supermultiplet is reviewed in the Kaehler superspace formalism and the complete supersymmetric action is constructed. This includes the classically Kaehler invariant component field action for all the kinetic terms as well as a Green-Schwarz type action which exhibits a non-holomorphic gauge coupling function. (author) 32 refs

  6. Classical solutions in supergravity

    International Nuclear Information System (INIS)

    Baaklini, N.S.; Ferrara, S.; Nieuwenhuizen Van, P.

    1977-06-01

    Classical solutions of supergravity are obtained by making finite global supersymmetry rotation on known solutions of the field equations of the bosonic sector. The Schwarzschild and the Reissner-Nordstoem solutions of general relativity are extended to various supergravity systems and the modification to the perihelion precession of planets is discussed

  7. Constrained superfields in supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Dall’Agata, Gianguido; Farakos, Fotis [Dipartimento di Fisica ed Astronomia “Galileo Galilei”, Università di Padova,Via Marzolo 8, 35131 Padova (Italy); INFN, Sezione di Padova,Via Marzolo 8, 35131 Padova (Italy)

    2016-02-16

    We analyze constrained superfields in supergravity. We investigate the consistency and solve all known constraints, presenting a new class that may have interesting applications in the construction of inflationary models. We provide the superspace Lagrangians for minimal supergravity models based on them and write the corresponding theories in component form using a simplifying gauge for the goldstino couplings.

  8. Minimal constrained supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Cribiori, N. [Dipartimento di Fisica e Astronomia “Galileo Galilei”, Università di Padova, Via Marzolo 8, 35131 Padova (Italy); INFN, Sezione di Padova, Via Marzolo 8, 35131 Padova (Italy); Dall' Agata, G., E-mail: dallagat@pd.infn.it [Dipartimento di Fisica e Astronomia “Galileo Galilei”, Università di Padova, Via Marzolo 8, 35131 Padova (Italy); INFN, Sezione di Padova, Via Marzolo 8, 35131 Padova (Italy); Farakos, F. [Dipartimento di Fisica e Astronomia “Galileo Galilei”, Università di Padova, Via Marzolo 8, 35131 Padova (Italy); INFN, Sezione di Padova, Via Marzolo 8, 35131 Padova (Italy); Porrati, M. [Center for Cosmology and Particle Physics, Department of Physics, New York University, 4 Washington Place, New York, NY 10003 (United States)

    2017-01-10

    We describe minimal supergravity models where supersymmetry is non-linearly realized via constrained superfields. We show that the resulting actions differ from the so called “de Sitter” supergravities because we consider constraints eliminating directly the auxiliary fields of the gravity multiplet.

  9. From supergravity to antigravity

    International Nuclear Information System (INIS)

    Scherk, J.

    1979-01-01

    All known extended supergravity models are shown to lead to a short range cancellation of the gravitational attraction between pairs of particles, a phenomenon known by the name 'Antigravity'. A phenomenological model of antigravity based on supergravity models is proposed where the carrier of the antigravitational force is a spin 1 particle (graviphoton). (Auth.)

  10. Applied supersymmetry and supergravity

    International Nuclear Information System (INIS)

    Nanopoulos, D.V.

    1986-01-01

    The structure and physical consequences of global and local supersymmetric (SUSY) gauge theories are reviewed. Motivation for SUSY theories, supersymmetry and its physical properties, the observable consequences of SUSY at low energies and super-high energies, physical structure of simple (N=1) supergravity, physics with simple (N=1) supergravity, and the experimental evidence for supersymmetry, are all discussed. (UK)

  11. Minimal constrained supergravity

    Directory of Open Access Journals (Sweden)

    N. Cribiori

    2017-01-01

    Full Text Available We describe minimal supergravity models where supersymmetry is non-linearly realized via constrained superfields. We show that the resulting actions differ from the so called “de Sitter” supergravities because we consider constraints eliminating directly the auxiliary fields of the gravity multiplet.

  12. Minimal constrained supergravity

    International Nuclear Information System (INIS)

    Cribiori, N.; Dall'Agata, G.; Farakos, F.; Porrati, M.

    2017-01-01

    We describe minimal supergravity models where supersymmetry is non-linearly realized via constrained superfields. We show that the resulting actions differ from the so called “de Sitter” supergravities because we consider constraints eliminating directly the auxiliary fields of the gravity multiplet.

  13. Supersymmetry and supergravity

    International Nuclear Information System (INIS)

    West, P.

    1986-01-01

    This book presents a pedagogical introduction of supersymmetry, supergravity and string theories and deals with advanced related topics. Contents: Introduction, The Supersymmetry Algebras; Alternative Approach to the Supersymmetry Algebra; Immediate Consequences of the Supersymmetry Algebra; The Wess-Zumino Model; N = 1 Super QED; N = 1 Super Yang-Mills Theory and the Noether Procedure; Irreducible Representations of Supersymmetry; Simple Supergravity; Invariance of Simple Supergravity; Tensor Calculus of Rigid Supersymmetry; Theories of Extended Rigid Supersymmetry; Local Tensor Calculus and the Coupling of Supergravity to Matter; Superspace; Superspace Formulations of Rigid Supersymmetric Theories; Superspace Formulation of N = 1 Supergravity; N = 1 Super-Feynman Rules; Ultraviolet Properties of the Extended Rigid Supersymmetry Theories; Spontaneous Breaking of Supersymmetry and Realistic Models; Currents in Supersymmetric Theories; Two-Dimensional Supersymmetry Models; Gauge Covariant Formulation of Strings; Appendix A: An Explanation of Our Choices of Conventions; Appendix B: A List of Reviews and Books

  14. d=8 supergravity

    International Nuclear Information System (INIS)

    Salam, A.; Sezgin, E.

    1984-10-01

    SU(2) gauged N=2 supergravity in d=8 is constructed by generalized dimensional reduction of d=11 supergravity on SU(2) group manifold. The relation between the field equations of the d=8 and those of d=11 supergravities is established. As a byproduct of this, it is shown that certain compactifications of d=11 supergravity give rise to anti-de Sitter space-time (AdS)xS 4 or AdSxCP 2 (with or without SU(2) instanton) or AdSxS 2 xS 2 compactifications of d=8 supergravity. The latter two solutions have no supersymmetry, while AdSxS 4 has N=0 or N=1 supersymmetry. (author)

  15. Introduction to supergravity

    CERN Document Server

    Tanii, Yoshiaki

    2014-01-01

    This book is a pedagogical introduction to supergravity, a gravitational field theory that includes supersymmetry (symmetry between bosons and fermions) and is a generalization of Einstein's general relativity. Supergravity provides a low-energy effective theory of superstring theory, which has attracted much attention as a candidate for the unified theory of fundamental particles, and it is a useful tool for studying non-perturbative properties of superstring theory such as D-branes and string duality. This work considers classical supergravities in four and higher spacetime dimensions with their applications to superstring theory in mind. More concretely, it discusses classical Lagrangians (or field equations) and symmetry properties of supergravities. Besides local symmetries, supergravities often have global non-compact symmetries, which play a crucial role in their applications to superstring theory. One of the main features of this book is its detailed discussion of these non-compact symmetries. The aim...

  16. Conformal invariance in supergravity

    International Nuclear Information System (INIS)

    Bergshoeff, E.A.

    1983-01-01

    In this thesis the author explains the role of conformal invariance in supergravity. He presents the complete structure of extended conformal supergravity for N <= 4. The outline of this work is as follows. In chapter 2 he briefly summarizes the essential properties of supersymmetry and supergravity and indicates the use of conformal invariance in supergravity. The idea that the introduction of additional symmetry transformations can make clear the structure of a field theory is not reserved to supergravity only. By means of some simple examples it is shown in chapter 3 how one can always introduce additional gauge transformations in a theory of massive vector fields. Moreover it is shown how the gauge invariant formulation sometimes explains the quantum mechanical properties of the theory. In chapter 4 the author defines the conformal transformations and summarizes their main properties. He explains how these conformal transformations can be used to analyse the structure of gravity. The supersymmetric extension of these results is discussed in chapter 5. Here he describes as an example how N=1 supergravity can be reformulated in a conformally-invariant way. He also shows that beyond N=1 the gauge fields of the superconformal symmetries do not constitute an off-shell field representation of extended conformal supergravity. Therefore, in chapter 6, a systematic method to construct the off-shell formulation of all extended conformal supergravity theories with N <= 4 is developed. As an example he uses this method to construct N=1 conformal supergravity. Finally, in chapter 7 N=4 conformal supergravity is discussed. (Auth.)

  17. Warped AdS{sub 6}×S{sup 2} in Type IIB supergravity II: global solutions and five-brane webs

    Energy Technology Data Exchange (ETDEWEB)

    D’Hoker, Eric; Gutperle, Michael; Uhlemann, Christoph F. [Mani L. Bhaumik Institute for Theoretical Physics,Department of Physics and Astronomy, University of California Los Angeles,475 Portola Plaza, Los Angeles, CA 90095 (United States)

    2017-05-23

    Motivated by the construction of holographic duals to five-dimensional superconformal quantum field theories, we obtain global solutions to Type IIB supergravity invariant under the superalgebra F(4) on a space-time of the form AdS{sub 6}×S{sup 2} warped over a two-dimensional Riemann surface Σ. In earlier work, the general local solutions were expressed in terms of two locally holomorphic functions A{sub ±} on Σ and global solutions were sketched when Σ is a disk. In the present paper, the physical regularity conditions on the supergravity fields required for global solutions are implemented on A{sub ±} for arbitrary Σ. Global solutions exist only when Σ has a non-empty boundary ∂Σ. The differentials ∂A{sub ±} are allowed to have poles only on ∂Σ and each pole corresponds to a semi-infinite (p,q) five-brane. The construction for the disk is carried out in detail and the conditions for the existence of global solutions are articulated for surfaces with more than one boundary and higher genus.

  18. Domain-induced activation of human phospholipase A2 type IIA: Local versus global lipid composition

    DEFF Research Database (Denmark)

    Leidy, C.; Linderoth, L.; Andresen, T.L.

    2006-01-01

    , we show that local enrichment of anionic lipids into fluid domains triggers PLA(2)-IIA activity. In addition, the compositional range of enzyme activity is shown to be related to the underlying lipid phase diagram. A comparison is done between PLA(2)-IIA and snake venom PLA(2), which in contrast...... to PLA(2)-IIA hydrolyzes both anionic and zwitterionic membranes. In general, this work shows that PLA(2)-IIA activation can be accomplished through local enrichment of anionic lipids into domains, indicating a mechanism for PLA(2)-IIA to target perturbed native membranes with low global anionic lipid...

  19. Supersymmetric and supergravity theories

    International Nuclear Information System (INIS)

    Pernici, M.

    1986-01-01

    The author addressed problems in Kaluza-Klein supergravity, in supersymmetric theories and in string theories. They constructed the following supergravity theories in higher dimensions: the maximal gauged supergravities in five and seven dimensions, both related to the respective ungauged theory, though the latter cannot be obtained by putting the coupling constant of the gauged version to zero (gauge discontinuity); the ten-dimensional N = 2 non-chiral and the six-dimensional N = 4 supergravities, through trivial dimensional reduction of higher dimensional theories. They studied the Kaluza-Klein compactifications of the seven-dimensional supergravity theories and of the ten-dimensional, N = 2 non-chiral supergravity. They obtained the non-compact gaugings and the critical points of the potential of the maximal gauged supergravity in seven dimensions. They computed the non-abelian chiral anomaly in super Yang-Mills theories, using a variation of the Fujikawa method. The covariant action of the SU(2) spinning string is obtained together with its extension to non-linear sigma models. A covariant action for the free open spinning string field theory is constructed by analyzing the BRST transformations

  20. Is vitamin D hypothesis for schizophrenia valid? Independent segregation of psychosis in a family with vitamin-D-dependent rickets type IIA.

    Science.gov (United States)

    Ozer, Suzan; Uluşahin, Aylin; Ulusoy, Semra; Okur, Hamza; Coşkun, Turgay; Tuncali, Timur; Göğüş, Ahmet; Akarsu, A Nurten

    2004-03-01

    The vitamin D hypothesis of schizophrenia is a recent concept bringing together old observations on environmental risk factors and new findings on the neurodevelopmental effects of vitamin D. Candidate genes related to the vitamin D endocrine system have not yet been fully explored for this purpose. The coexistence of vitamin-D-dependent-rickets type II with alopecia (VDDR IIA) and different forms of psychosis in the same inbred family has provided us with an opportunity to investigate the presumed relationship between vitamin D deficiency and psychosis. Psychiatric examination and molecular genetic studies were performed in this family overloaded with psychotic disorders and VDDR IIA. Forty members were evaluated in order to describe their phenotypic features. The family was tested for a linkage to the chromosome 12q12-q14 region where the vitamin D receptor (VDR) gene is located. Psychosis was the common phenotype in the 18 psychiatrically affected members. Pedigree analysis did not show a cosegregation of psychosis and rickets. Lod scores were not significant to prove a linkage between psychosis and VDR locus. The authors concluded that (1) the neurodevelopmental consequences of vitamin D deficiency do not play a causative role in psychotic disorders, (2) these two syndromes are inherited independently, and (3) vitamin D deficiency does not act as a risk factor in subjects susceptible to psychosis.

  1. Supersymmetry, supergravity, and unification

    CERN Document Server

    Nath, Pran

    2017-01-01

    This unique book gives a modern account of particle physics and gravity based on supersymmetry and supergravity, two of the most significant developments in theoretical physics since general relativity. The book begins with a brief overview of the history of unification and then goes into a detailed exposition of both fundamental and phenomenological topics. The topics in fundamental physics include Einstein gravity, Yang-Mills theory, anomalies, the standard model, supersymmetry and supergravity, and the construction of supergravity couplings with matter and gauge fields, as well as computational techniques for SO(10) couplings. The topics of phenomenological interest include implications of supergravity models at colliders, CP violation, and proton stability, as well as topics in cosmology such as inflation, leptogenesis, baryogenesis, and dark matter. The book is intended for graduate students and researchers seeking to master the techniques for building grand unified models.

  2. Supersymmetry and supergravity

    International Nuclear Information System (INIS)

    Wess, J.; Bagger, J.

    1992-01-01

    The first edition of this book appeared in 1983 and was based on a series of lectures given at Princeton in 1983 by Julius Wess. Since the appearance of the first edition much work has been done on the development of phenomenological models of particle behavior based on the supergravity multiplet. Some experimental searches have been carried out and others are planned for the future. For this reason the second edition of the book goes substantially beyond the first. Six new chapters have been added for a total of twenty-six and five new appendices for a total of seven. The new chapters and appendices are primarily aimed at deriving the most general supersymmetric gauge invariant theory of chiral fields interacting with supergravity and expressing it in component form. The book is divided into three sections. After a brief introduction, the first part of the book deals with a description of N=1 supersymmetric non-abelian rigid gauge theory of chiral fields. The second part of the book develops a local supersymmetric theory which is supergravity. The final part describes the coupling of supersymmetric chiral fields to supergravity in a gauge invariant way. The book may be recommended as a pedagogical introduction to the theory of N=1 supergravity. Together with the appendices is is completely self-contained, both in notation and in the concepts used, requiring only some knowledge of field theory as a background

  3. A short review of supergravity

    International Nuclear Information System (INIS)

    Scherk, J.

    1980-01-01

    The perennial question: 'Why fermions' finally answered. A dictionnary of Superwords. The Superalgebras used by Supersymmetrists. The representations of the Super Poincare algebra. What is Super about Supergravity. Extra spatial dimensions and Supergravity. Physical content of the N=8 model. General features of a Supersymmetric World. Antigravity and Supergravity: a crazy idea. Conclusion left to a well-known physicist

  4. Supersymmetric RG flows and Janus from type II orbifold compactification

    Energy Technology Data Exchange (ETDEWEB)

    Karndumri, Parinya; Upathambhakul, Khem [Chulalongkorn University, String Theory and Supergravity Group, Department of Physics, Faculty of Science, Bangkok (Thailand)

    2017-07-15

    We study holographic RG flow solutions within four-dimensional N = 4 gauged supergravity obtained from type IIA and IIB string theories compactified on T{sup 6}/Z{sub 2} x Z{sub 2} orbifold with gauge, geometric and non-geometric fluxes. In type IIB non-geometric compactifications, the resulting gauged supergravity has ISO(3) x ISO(3) gauge group and admits an N = 4 AdS{sub 4} vacuum dual to an N = 4 superconformal field theory (SCFT) in three dimensions. We study various supersymmetric RG flows from this N = 4 SCFT to N = 4 and N = 1 non-conformal field theories in the IR. The flows preserving N = 4 supersymmetry are driven by relevant operators of dimensions Δ = 1, 2 or alternatively by one of these relevant operators, dual to the dilaton, and irrelevant operators of dimensions Δ = 4 while the N = 1 flows in addition involve marginal deformations. Most of the flows can be obtained analytically. We also give examples of supersymmetric Janus solutions preserving N = 4 and N = 1 supersymmetries. These solutions should describe two-dimensional conformal defects within the dual N = 4 SCFT. Geometric compactifications of type IIA theory give rise to N = 4 gauged supergravity with ISO(3) x U(1){sup 6} gauge group. In this case, the resulting gauged supergravity admits an N = 1 AdS{sub 4} vacuum. We also numerically study possible N = 1 RG flows to non-conformal field theories in this case. (orig.)

  5. Flatspace chiral supergravity

    Science.gov (United States)

    Bagchi, Arjun; Basu, Rudranil; Detournary, Stéphane; Parekh, Pulastya

    2018-05-01

    We propose a holographic duality between a 2 dimensional (2d) chiral superconformal field theory and a certain theory of supergravity in 3d with flatspace boundary conditions that is obtained as a double scaling limit of a parity breaking theory of supergravity. We show how the asymptotic symmetries of the bulk theory reduce from the "despotic" super Bondi-Metzner-Sachs algebra (or equivalently the inhomogeneous super Galilean conformal algebra) to a single copy of the super-Virasoro algebra in this limit and also reproduce the same reduction from a study of null vectors in the putative 2d dual field theory.

  6. Null cone superspace supergravity

    International Nuclear Information System (INIS)

    Downes-Martin, S.G.

    1980-03-01

    The null cone formalism is used to derive a 2(N-1) parameter family of constraints for O(N) extended superspace supergravity. The invariance groups of these constraints is analysed and is found to be [subgroup U submanifold] contains GL(4,R) for N = 1, the submanifold being eliminated for N > 1. The invariance group defines non-Weyl rotations on the superbein which combine to form Weyl transformations on the supertangent space metric. The invariance of the supergravity Lagrangian under these transformations is discussed. (Auth.)

  7. Quantum supergravity, supergravity anomalies and string phenomenology

    Energy Technology Data Exchange (ETDEWEB)

    Gaillard, Mary K., E-mail: mkgaillard@lbl.gov

    2016-11-15

    I discuss the role of quantum effects in the phenomenology of effective supergravity theories from compactification of the weakly coupled heterotic string. An accurate incorporation of these effects requires a regularization procedure that respects local supersymmetry and BRST invariance and that retains information associated with the cut-off scale, which has physical meaning in an effective theory. I briefly outline the Pauli–Villars regularization procedure, describe some applications, and comment on what remains to be done to fully define the effective quantum field theory.

  8. Vacuum state supersymmetry in d=11 supergravity

    International Nuclear Information System (INIS)

    Vasilevich, D.V.

    1987-01-01

    Supersymmetry of vacuum state in d=11 supergravity is considered. Proceeding on sufficiently general assumptions relatively superformation parameter only Freud-Rubin type solutions may possess supersymmetries. To obtain this result no restrictions on the form of superformation parameter, supealgebra of vacuum global supersymmetry and the form of boson fields were imposed

  9. Dynamical symmetry enhancement near IIA horizons

    International Nuclear Information System (INIS)

    Gran, University; Gutowski, J.; Kayani, University; Papadopoulos, G.

    2015-01-01

    We show that smooth type IIA Killing horizons with compact spatial sections preserve an even number of supersymmetries, and that the symmetry algebra of horizons with non-trivial fluxes includes an sl(2,ℝ) subalgebra. This confirms the conjecture of http://dx.doi.org/10.1007/JHEP11(2013)104 for type IIA horizons. As an intermediate step in the proof, we also demonstrate new Lichnerowicz type theorems for spin bundle connections whose holonomy is contained in a general linear group.

  10. Supergravities and superstrings

    International Nuclear Information System (INIS)

    Ferrara, S.

    1988-01-01

    In this paper supergavity theories emerging as the point-field limit of various superstring compactifications are considered, and the higher-order corrections to the standard supergravity Lagrangians are discussed. The structure of the effective Lagrangian for the recently constructed four-dimensional superstring models is also reported

  11. A combination of two truncating mutations in USH2A causes more severe and progressive hearing impairment in Usher syndrome type IIa.

    Science.gov (United States)

    Hartel, Bas P; Löfgren, Maria; Huygen, Patrick L M; Guchelaar, Iris; Lo-A-Njoe Kort, Nicole; Sadeghi, Andre M; van Wijk, Erwin; Tranebjærg, Lisbeth; Kremer, Hannie; Kimberling, William J; Cremers, Cor W R J; Möller, Claes; Pennings, Ronald J E

    2016-09-01

    Usher syndrome is an inherited disorder that is characterized by hearing impairment (HI), retinitis pigmentosa, and in some cases vestibular dysfunction. Usher syndrome type IIa is caused by mutations in USH2A. HI in these patients is highly heterogeneous and the present study evaluates the effects of different types of USH2A mutations on the audiometric phenotype. Data from two large centres of expertise on Usher Syndrome in the Netherlands and Sweden were combined in order to create a large combined sample of patients to identify possible genotype-phenotype correlations. A retrospective study on HI in 110 patients (65 Dutch and 45 Swedish) genetically diagnosed with Usher syndrome type IIa. We used methods especially designed for characterizing and testing differences in audiological phenotype between patient subgroups. These methods included Age Related Typical Audiograms (ARTA) and a method to evaluate the difference in the degree of HI developed throughout life between subgroups. Cross-sectional linear regression analysis of last-visit audiograms for the best hearing ear demonstrated a gradual decline of hearing over decades. The congenital level of HI was in the range of 16-33 dB at 0.25-0.5 kHz, and in the range of 51-60 dB at 1-8 kHz. The annual threshold deterioration was in the range of 0.4-0.5 dB/year at 0.25-2 kHz and in the range of 0.7-0.8 dB/year at 4-8 kHz. Patients with two truncating mutations, including homozygotes for the common c.2299delG mutation, developed significantly more severe HI throughout life than patients with one truncating mutation combined with one nontruncating mutation, and patients with two nontruncating mutations. The results have direct implications for patient counselling in terms of prognosis of hearing and may serve as baseline measures for future (genetic) therapeutic interventions. Copyright © 2016 Elsevier B.V. All rights reserved.

  12. Supergravity duals of matrix string theory

    International Nuclear Information System (INIS)

    Morales, Jose F.; Samtleben, Henning

    2002-01-01

    We study holographic duals of type II and heterotic matrix string theories described by warped AdS 3 supergravities. By explicitly solving the linearized equations of motion around near horizon D-string geometries, we determine the spectrum of Kaluza-Klein primaries for type I, II supergravities on warped AdS 3 xS 7 . The results match those coming from the dual two-dimensional gauge theories living on the D-string worldvolumes. We briefly discuss the connections with the N=(8,8), N=(8,0) orbifold superconformal field theories to which type IIB/heterotic matrix strings flow in the infrared. In particular, we associate the dimension (h,h-bar) (32,32) twisted operator which brings the matrix string theories out from the conformal point (R; 8 ) N /S N with the dilaton profile in the supergravity background. The familiar dictionary between masses and 'scaling' dimensions of field and operators are modified by the presence of non-trivial warp factors and running dilatons. These modifications are worked out for the general case of domain wall/QFT correspondences between supergravities on warped AdS d+1 xS q geometries and super Yang-Mills theories with 16 supercharges. (author)

  13. Type IIB supergravity solution for the T-dual of the η-deformed AdS_5×S"5 superstring

    International Nuclear Information System (INIS)

    Hoare, B.; Tseytlin, A.A.

    2015-01-01

    We find an exact type IIB supergravity solution that represents a one-parameter deformation of the T-dual of the AdS_5×S"5 background (with T-duality applied in all 6 abelian bosonic isometric directions). The non-trivial fields are the metric, dilaton and RR 5-form only. The latter has remarkably simple “undeformed” form when written in terms of a “deformation-rotated” vielbein basis. An unusual feature of this solution is that the dilaton contains a linear dependence on the isometric coordinates of the metric precluding a straightforward reversal of T-duality. If we still formally dualize back, we find exactly the metric, B-field and product of dilaton with RR field strengths as recently extracted from the η-deformed AdS_5×S"5 superstring action in http://arxiv.org/abs/1507.04239. We also discuss similar solutions for deformed AdS_n×S"n backgrounds with n=2,3. In the η→i limit we demonstrate that all these backgrounds can be interpreted as special limits of gauged WZW models and are also related to (a limit of) the Pohlmeyer-reduced models of the AdS_n×S"n superstrings.

  14. Type IIA string theory on T"6/(Z_2 x Z_6 x ΩR). Model building and string phenomenology with intersecting D6-branes

    International Nuclear Information System (INIS)

    Ecker, Jill

    2016-01-01

    In this doctoral thesis, various aspects of string model building and phenomenology are investigated within the framework of Type IIA string theory on the T"6/(Z_2 x Z_6 x ΩR) orbifold with discrete torsion. The aim is the reproduction of supersymmetric versions of well-known particle physics models using intersecting rigid D6-branes wrapped on fractional three-cycles. The models analyzed include the minimal supersymmetric Standard Model as well as supersymmetric Pati-Salam models, left-right symmetric models and SU(5) models. Systematic computer scans test numerous combinations of intersecting D6-branes in order to detect those that give rise to the correct chiral particle content of the considered models. For each type of the afore mentioned models, concrete examples will be found which satisfy the constraints on the particle spectrum and fulfill all consistency conditions. Finally, the thesis focuses on phenomenological aspects of the particle physics models found, including the detection of massless U(1) combinations, discrete Z_n-symmetries and cubic couplings such as the Yukawa couplings.

  15. Higher Curvature Supergravity, Supersymmetry Breaking and Inflation

    CERN Document Server

    Ferrara, Sergio

    2017-01-01

    In these lectures, after a short introduction to cosmology, we discuss the supergravity embedding of higher curvature models of inflation. The supergravity description of such models is presented for the two different formulations of minimal supergravity.

  16. On the worldsheet theory of the type IIA {text{Ad}}{{text{S}}_4} × mathbb{C}{mathbb{P}_3} superstring

    Science.gov (United States)

    Sundin, Per

    2010-04-01

    We perform a detailed study of the type IIA superstring in {text{Ad}}{{text{S}}_4} × mathbb{C}{mathbb{P}_3} . After introducing suitable bosonic light-cone and fermionic kappa worldsheet gauges we derive the pure boson and fermion SU(2|2)×U(1) covariant light-cone Hamiltonian up to quartic order in fields. As a first application of our derivation we calculate energy shifts for string configurations in a closed fermionic subsector and successfully match these with a set of light-cone Bethe equations. We then turn to investigate the mismatch between the degrees of freedom of scattering states and oscillatory string modes. Since only light string modes appear as fundamental Bethe roots in the scattering theory, the physical role of the remaining 4 F + 4 B massive oscillators is rather unclear. By continuing a line of research initiated by Zarembo, we shed light on this question by calculating quantum corrections for the propagators of the bosonic massive fields. We show that, once loop corrections are incorporated, the massive coordinates dissolve in a continuum state of two light particles.

  17. A soluble activin type IIA receptor mitigates the loss of femoral neck bone strength and cancellous bone mass in a mouse model of disuse osteopenia.

    Science.gov (United States)

    Lodberg, Andreas; Eijken, Marco; van der Eerden, Bram C J; Okkels, Mette Wendelboe; Thomsen, Jesper Skovhus; Brüel, Annemarie

    2018-05-01

    Disuse causes a rapid and substantial bone loss distinct in its pathophysiology from the bone loss associated with cancers, age, and menopause. While inhibitors of the activin-receptor signaling pathway (IASPs) have been shown to prevent ovariectomy- and cancer-induced bone loss, their application in a model of disuse osteopenia remains to be tested. Here, we show that a soluble activin type IIA receptor (ActRIIA-mFc) increases diaphyseal bone strength and cancellous bone mass, and mitigates the loss of femoral neck bone strength in the Botulinum Toxin A (BTX)-model of disuse osteopenia in female C57BL/6J mice. We show that ActRIIA-mFc treatment preferentially stimulates a dual-effect (anabolic-antiresorptive) on the periosteal envelope of diaphyseal bone, demonstrating in detail the effects of ActRIIA-mFc on cortical bone. These observations constitute a previously undescribed feature of IASPs that mediates at least part of their ability to mitigate detrimental effects of unloading on bone tissue. The study findings support the application of IASPs as a strategy to combat bone loss during disuse. Copyright © 2018 Elsevier Inc. All rights reserved.

  18. Is supergravity well-posed?

    International Nuclear Information System (INIS)

    Isenberg, J.; Bao, D.; Yasskin, P.B.

    1983-01-01

    One rather fundamental question concerning supergravity remains unresolved: Is supergravity a well-posed field theory? That is, does a set of certain (Cauchy) data specified on some initial spacelike surface determine a unique, causally propagating spacetime solution of the supergravity field equations (at least in some finite neighborhood of the initial surface)? In this paper, the authors give a very brief report on work directed towards answering this question. (Auth.)

  19. Supergravity constraints on monojets

    International Nuclear Information System (INIS)

    Nandi, S.

    1986-01-01

    In the standard model, supplemented by N = 1 minimal supergravity, all the supersymmetric particle masses can be expressed in terms of a few unknown parameters. The resulting mass relations, and the laboratory and the cosmological bounds on these superpartner masses are used to put constraints on the supersymmetric origin of the CERN monojets. The latest MAC data at PEP excludes the scalar quarks, of masses up to 45 GeV, as the origin of these monojets. The cosmological bounds, for a stable photino, excludes the mass range necessary for the light gluino-heavy squark production interpretation. These difficulties can be avoided by going beyond the minimal supergravity theory. Irrespective of the monojets, the importance of the stable γ as the source of the cosmological dark matter is emphasized

  20. Grand unification and supergravity

    International Nuclear Information System (INIS)

    Nanopoulos, D.V.

    Grand Unified Theories (GUTs) are very successful, but they suffer from fine-tuning or hierarchy problems. It seems that more symmetry beyond the gauge symmetry is needed and indeed supersymmetric GUTs may provide the correct framework in solving the hierarchy problems. These are reviewed. From the results discussed, it is seen that for the first time in particle physics, gravity seems to play a dominant role. It may be responsible for GUT breaking, SU(2) x U(1) breaking, fermion masses, proton decay and a consistent cosmological picture. Supergravity seems to offer a consistent, effective theory for energies below the Planck scale to N=1 local SUSY but also, in the context of N=8 extended supergravity with a dynamically realized SU(8), there may be a consistent fundamental unified theory of all interactions. (U.K.)

  1. Inflaton decay in supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Endo, M.; Takahashi, F. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Yanagida, T.T. [Tokyo Univ. (Japan). Dept. of Physics]|[Tokyo Univ. (Japan). Research Center for the Early Universe

    2007-06-15

    We discuss inflaton decay in supergravity, taking account of the gravitational effects. It is shown that, if the inflaton has a nonzero vacuum expectation value, it generically couples to any matter fields that appear in the superpotential at the tree level, and to any gauge sectors through anomalies in the supergravity. Through these processes, the inflaton generically decays into the supersymmetry breaking sector, producing many gravitinos. The inflaton also directly decays into a pair of the gravitinos. We derive constraints on both inflation models and supersymmetry breaking scenarios for avoiding overproduction of the gravitinos. Furthermore, the inflaton naturally decays into the visible sector via the top Yukawa coupling and SU(3){sub C} gauge interactions. (orig.)

  2. Inflaton decay in supergravity

    International Nuclear Information System (INIS)

    Endo, M.; Takahashi, F.; Yanagida, T.T.; Tokyo Univ.

    2007-06-01

    We discuss inflaton decay in supergravity, taking account of the gravitational effects. It is shown that, if the inflaton has a nonzero vacuum expectation value, it generically couples to any matter fields that appear in the superpotential at the tree level, and to any gauge sectors through anomalies in the supergravity. Through these processes, the inflaton generically decays into the supersymmetry breaking sector, producing many gravitinos. The inflaton also directly decays into a pair of the gravitinos. We derive constraints on both inflation models and supersymmetry breaking scenarios for avoiding overproduction of the gravitinos. Furthermore, the inflaton naturally decays into the visible sector via the top Yukawa coupling and SU(3) C gauge interactions. (orig.)

  3. Covariant field equations in supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Vanhecke, Bram [KU Leuven, Institute for Theoretical Physics, Leuven (Belgium); Ghent University, Faculty of Physics, Gent (Belgium); Proeyen, Antoine van [KU Leuven, Institute for Theoretical Physics, Leuven (Belgium)

    2017-12-15

    Covariance is a useful property for handling supergravity theories. In this paper, we prove a covariance property of supergravity field equations: under reasonable conditions, field equations of supergravity are covariant modulo other field equations. We prove that for any supergravity there exist such covariant equations of motion, other than the regular equations of motion, that are equivalent to the latter. The relations that we find between field equations and their covariant form can be used to obtain multiplets of field equations. In practice, the covariant field equations are easily found by simply covariantizing the ordinary field equations. (copyright 2017 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  4. Covariant field equations in supergravity

    International Nuclear Information System (INIS)

    Vanhecke, Bram; Proeyen, Antoine van

    2017-01-01

    Covariance is a useful property for handling supergravity theories. In this paper, we prove a covariance property of supergravity field equations: under reasonable conditions, field equations of supergravity are covariant modulo other field equations. We prove that for any supergravity there exist such covariant equations of motion, other than the regular equations of motion, that are equivalent to the latter. The relations that we find between field equations and their covariant form can be used to obtain multiplets of field equations. In practice, the covariant field equations are easily found by simply covariantizing the ordinary field equations. (copyright 2017 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  5. Noncompact N=2 supergravity

    International Nuclear Information System (INIS)

    Wit, B. de; Lauwers, P.G.; Philippe, R.; Van Proeyen, A.

    1983-10-01

    A massive spin-1 multiplet with central charge is coupled to N=2 supergravity. Compared to conventional gauge fields the anomalous magnetic moment of the spin-1 particles is of opposite sign. The construction of this theory is based on an N=2 supersymmetric gauge theory associated with the noncompact group SO(2,1). As a byproduct we present a convenient expression for the N=2 Einstein-Yang-Mills lagrangian. (Auth.)

  6. Simplifications of Einstein supergravity

    International Nuclear Information System (INIS)

    Ferrara, S.; van Nieuwenhuizen, P.

    1979-01-01

    Using a new symmetry of the Einstein supergravity action and defining a new spin connection, the axial-vector auxiliary field cancels in the gauge action and in the gauge algebra. This explains why in some models a first-order formalism with minimal coupling of the spin connection and tensor calculus agree, while in other models only the tensor calculus gives the correct result but torsion does not

  7. Massive Supergravity and Deconstruction

    CERN Document Server

    Gregoire, T; Shadmi, Y; Gregoire, Thomas; Schwartz, Matthew D; Shadmi, Yael

    2004-01-01

    We present a simple superfield Lagrangian for massive supergravity. It comprises the minimal supergravity Lagrangian with interactions as well as mass terms for the metric superfield and the chiral compensator. This is the natural generalization of the Fierz-Pauli Lagrangian for massive gravity which comprises mass terms for the metric and its trace. We show that the on-shell bosonic and fermionic fields are degenerate and have the appropriate spins: 2, 3/2, 3/2 and 1. We then study this interacting Lagrangian using goldstone superfields. We find that a chiral multiplet of goldstones gets a kinetic term through mixing, just as the scalar goldstone does in the non-supersymmetric case. This produces Planck scale (Mpl) interactions with matter and all the discontinuities and unitarity bounds associated with massive gravity. In particular, the scale of strong coupling is (Mpl m^4)^1/5, where m is the multiplet's mass. Next, we consider applications of massive supergravity to deconstruction. We estimate various qu...

  8. Newton-Cartan supergravity with torsion and Schrodinger supergravity

    NARCIS (Netherlands)

    Bergshoeff, Eric; Rosseel, Jan; Zojer, Thomas

    2015-01-01

    We derive a torsionfull version of three-dimensional N - 2 Newton-Cartan supergravity using a non-relativistic notion of the superconformal tensor calculus. The "superconformal" theory that we start with is Schrodinger supergravity which we obtain by gauging the Schrodinger superalgebra. We present

  9. Introduction to supersymmetry and supergravity

    International Nuclear Information System (INIS)

    West, P.

    1986-01-01

    This book gives views of supersymmetry and supergravity. The contents include; alternative approach to supersymmetry algebra; immediate consequences of supersymmetry algebra; Wess-Zumino model. N=1 Super QED. N=1 super Yang Mills theory and the Noether procedure; irreducible representations of supersymmetry; invariance of simple supergravity and theories of extended rigid supersymmetry

  10. Birth outcomes of cases with isolated atrial septal defect type II--a population-based case-control study.

    Science.gov (United States)

    Vereczkey, Attila; Kósa, Zsolt; Csáky-Szunyogh, Melinda; Urbán, Róbert; Czeizel, Andrew E

    2013-07-01

    In general, epidemiological studies have evaluated cases with congenital cardiovascular abnormalities together. The aim of this study is to describe the birth outcomes of cases with isolated/single atrial septal defect type II (ASD-II, i.e. only a fossa ovalis defect) after surgical correction or lethal outcome in the light of maternal sociodemographic data. Comparison of birth outcomes and maternal characteristics of cases with ASD-II and controls without defect. The population-based Hungarian Case-Control Surveillance of Congenital Abnormalities. Hungarian newborn infants with or without ASD-II. Medically recorded birth outcomes, maternal age and birth order were evaluated. Marital and employment status was based on maternal information. The lifestyle factors were analyzed in a subsample of mothers visited at home based on a personal interview with mothers and their close relatives, and the family consensus was accepted. Mean gestational age at delivery and birthweight, rate of preterm birth and low birthweight, maternal age, birth order, marital and employment status. The evaluation of 471 cases with ASD-II and 38,151 controls without any defects showed a female excess in cases with ASD-II, having shorter gestational age and lower mean birthweight, and thus a higher rate of preterm births and low birthweight. Intrauterine growth restriction and shorter gestational age were found in cases with ASD-II, particularly in female children. These factors may have a general developmental process in which there was not closure of the foramen ovale, thus echocardiographic screening of these babies might be of value. © 2012 The Authors Acta Obstetricia et Gynecologica Scandinavica © 2012 Nordic Federation of Societies of Obstetrics and Gynecology.

  11. Molecular cloning, expression and characterization of albolamin: a type P-IIa snake venom metalloproteinase from green pit viper (Cryptelytrops albolabris).

    Science.gov (United States)

    Jangprasert, Panchalee; Rojnuckarin, Ponlapat

    2014-03-01

    Snake venom metalloproteinases (SVMPs) can damage vessel wall, degrade clotting factors, inhibit integrins and block platelet functions. Studying them not only gives us deeper insights in pathogenesis of snakebites, but also potentially yields novel therapeutic agents. Here, we discovered a clone of an RGD-containing SVMP from the green pit viper (Cryptelytrops albolabris) venom gland cDNA library. Sequence analysis revealed that it belonged to the P-IIa subclass of SVMP comprising signal peptide, prodomain, metalloproteinase and disintegrin. Compared with other P-II SVMPs, it contained 2 additional conserved cysteines that were predicted to prevent the release of disintegrin from the metalloproteinase domain in the mature protein. The N-terminal histidine-tagged construct of metalloproteinase and disintegrin domains of albolamin was inserted into the pPICZαA vector and expressed in Pichia pastoris. The recombinant protein molecular weight was approximately 35 kDa on Western blot probed with anti-polyhistidine antibody. The recombinant albolamin could digest human type IV collagen starting within 15 min after incubation. In addition, it dose-dependently inhibited collagen-induced platelet aggregation with the IC50 of 1.8 μM. However, there was no effect on ADP-induced platelet aggregation. Therefore, the inhibition mechanism is probably through blocking collagen receptor(s). Albolamin activities probably contributed to pathology of green pit viper bites. Its disintegrin domain deserves further studies for the potential to be a useful agent affecting platelet functions. Copyright © 2013 Elsevier Ltd. All rights reserved.

  12. Higher curvature supergravity and cosmology

    Energy Technology Data Exchange (ETDEWEB)

    Ferrara, Sergio [Th-Ph Department, CERN, Geneva (Switzerland); U.C.L.A., Los Angeles, CA (United States); INFN - LNF, Frascati (Italy); Sagnotti, Augusto [Scuola Normale Superiore, Pisa (Italy); INFN, Pisa (Italy)

    2016-04-15

    In this contribution we describe dual higher-derivative formulations of some cosmological models based on supergravity. Work in this direction started with the R + R{sup 2} Starobinsky model, whose supersymmetric extension was derived in the late 80's and was recently revived in view of new CMB data. Models dual to higher-derivative theories are subject to more restrictions than their bosonic counterparts or standard supergravity. The three sections are devoted to a brief description of R + R{sup 2} supergravity, to a scale invariant R{sup 2} supergravity and to theories with a nilpotent curvature, whose duals describe non-linear realizations (in the form of a Volkov-Akulov constrained superfield) coupled to supergravity. (copyright 2015 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  13. ATP6V0A2 mutations present in two Mexican Mestizo children with an autosomal recessive cutis laxa syndrome type IIA

    Directory of Open Access Journals (Sweden)

    D. Bahena-Bahena

    2014-01-01

    Full Text Available Patients with ARCL-IIA harbor mutations in ATP6V0A2 that codes for an organelle proton pump. The ARCL-IIA syndrome characteristically presents a combined glycosylation defect affecting N-linked and O-linked glycosylations, differentiating it from other cutis laxa syndromes and classifying it as a Congenital Disorder of Glycosylation (ATP6V0A2-CDG. We studied two Mexican Mestizo patients with a clinical phenotype corresponding to an ARCL-IIA syndrome. Both patients presented abnormal transferrin (N-linked glycosylation but Patient 1 had a normal ApoCIII (O-linked glycosylation profile. Mutational screening of ATP6V0A2 using cDNA and genomic DNA revealed in Patient 1 a previously reported homozygous nonsense mutation c.187C>T (p.R63X associated with a novel clinical finding of a VSD. In Patient 2 we found a homozygous c.2293C>T (p.Q765X mutation that had been previously reported but found that it also altered RNA processing generating a novel transcript not previously identified (r.2176_2293del; p.F726Sfs*10. This is the first report to describe Mestizo patients with molecular diagnosis of ARCL-IIA/ATP6V0A2-CDG and to establish that their mutations are the first to be found in patients from different regions of the world and with different genetic backgrounds.

  14. Topologically massive supergravity

    Directory of Open Access Journals (Sweden)

    S. Deser

    1983-01-01

    Full Text Available The locally supersymmetric extension of three-dimensional topologically massive gravity is constructed. Its fermionic part is the sum of the (dynamically trivial Rarita-Schwinger action and a gauge-invariant topological term, of second derivative order, analogous to the gravitational one. It is ghost free and represents a single massive spin 3/2 excitation. The fermion-gravity coupling is minimal and the invariance is under the usual supergravity transformations. The system's energy, as well as that of the original topological gravity, is therefore positive.

  15. Constructive approach to supergravity

    International Nuclear Information System (INIS)

    Milton, K.A.; Urrutia, L.F.; Finkelstein, R.J.

    1980-01-01

    Starting from a first-order formulation of the Lagrangian of noninteracting massless helicity-2 and helicity-3/2 particles, global supersymmetry transformations are deduced. Then, allowing the supersymmetry transformations to become local requires, if supersymmetry is to be maintained, the introduction of a unique primitive interaction through the 'gravitino' stress tensor and torsion. Finally, the imposition of exact supersymmetry invariance leads by a short, constructive process to full supergravity and the complete form of the super-symmetry transformations. In particular, no explicit use is made of general coordinate invariance, and the self-consistency of the gravitational coupling emerges from the local supersymmetry requirement alone. (author)

  16. Gauged Supergravities and Spontaneous Supersymmetry Breaking from the Double Copy Construction

    Science.gov (United States)

    Chiodaroli, M.; Günaydin, M.; Johansson, H.; Roiban, R.

    2018-04-01

    Supergravities with gauged R symmetry and Minkowski vacua allow for spontaneous supersymmetry breaking and, as such, provide a framework for building supergravity models of phenomenological relevance. In this Letter, we initiate the study of double copy constructions for these supergravities. We argue that, on general grounds, we expect their scattering amplitudes to be described by a double copy of the type (spontaneously broken gauge theory)⊗ (gauge theory with broken supersymmetry). We present a simple realization in which the resulting supergravity has U (1 )R gauge symmetry, spontaneously broken N =2 supersymmetry, and massive gravitini. This is the first instance of a double copy construction of a gauged supergravity and of a theory with spontaneously broken supersymmetry. The construction extends in a straightforward manner to a large family of gauged Yang-Mills-Einstein supergravity theories with or without spontaneous gauge-symmetry breaking.

  17. A superstring field theory for supergravity

    Science.gov (United States)

    Reid-Edwards, R. A.; Riccombeni, D. A.

    2017-09-01

    A covariant closed superstring field theory, equivalent to classical tendimensional Type II supergravity, is presented. The defining conformal field theory is the ambitwistor string worldsheet theory of Mason and Skinner. This theory is known to reproduce the scattering amplitudes of Cachazo, He and Yuan in which the scattering equations play an important role and the string field theory naturally incorporates these results. We investigate the operator formalism description of the ambitwsitor string and propose an action for the string field theory of the bosonic and supersymmetric theories. The correct linearised gauge symmetries and spacetime actions are explicitly reproduced and evidence is given that the action is correct to all orders. The focus is on the NeveuSchwarz sector and the explicit description of tree level perturbation theory about flat spacetime. Application of the string field theory to general supergravity backgrounds and the inclusion of the Ramond sector are briefly discussed.

  18. Scattering equations, supergravity integrands, and pure spinors

    Energy Technology Data Exchange (ETDEWEB)

    Adamo, Tim; Casali, Eduardo [Department of Applied Mathematics & Theoretical Physics, University of Cambridge, Wilberforce Road, Cambridge CB3 0WA (United Kingdom)

    2015-05-25

    The tree-level S-matrix of type II supergravity can be computed in scattering equation form by correlators in a worldsheet theory analogous to a chiral, infinite tension limit of the pure spinor formalism. By defining a non-minimal version of this theory, we give a prescription for computing correlators on higher genus worldsheets which manifest space-time supersymmetry. These correlators are conjectured to provide the loop integrands of supergravity scattering amplitudes, supported on the scattering equations. We give non-trivial evidence in support of this conjecture at genus one and two with four external states. Throughout, we find a close correspondence with the pure spinor formalism of superstring theory, particularly regarding regulators and zero-mode counting.

  19. Scattering equations, supergravity integrands, and pure spinors

    International Nuclear Information System (INIS)

    Adamo, Tim; Casali, Eduardo

    2015-01-01

    The tree-level S-matrix of type II supergravity can be computed in scattering equation form by correlators in a worldsheet theory analogous to a chiral, infinite tension limit of the pure spinor formalism. By defining a non-minimal version of this theory, we give a prescription for computing correlators on higher genus worldsheets which manifest space-time supersymmetry. These correlators are conjectured to provide the loop integrands of supergravity scattering amplitudes, supported on the scattering equations. We give non-trivial evidence in support of this conjecture at genus one and two with four external states. Throughout, we find a close correspondence with the pure spinor formalism of superstring theory, particularly regarding regulators and zero-mode counting.

  20. sPLA2-IIA

    Indian Academy of Sciences (India)

    67

    Recent research showed that maslinic acid interacts with sPLA2-IIA ... Further analysis revealed that sPLA2-IIA only induced modest LDL ..... MDA/mg protein) compared to native LDL (2.043 nmol MDA/mg protein) while .... to modify extracellular non-cellular lipid components such as lipoproteins, ... The main pathway for.

  1. Structure of a supergravity group

    International Nuclear Information System (INIS)

    Ogievetsky, V.; Sokatchev, E.

    1978-01-01

    The supergravity group is found to be the direct product of general covariance groups in complex conjugated left and right handed superspaces. The ordinary space-time coordinate and the axial gravitational superfield are the real and imaginary parts of the complex coordinate, respectively. It is pointed out that a number of questions concerning the formalism remains open. For instance how to define superfields with external indices, supercovariant derivatives and invariants of the group, etc. However, the extremely simple and clear geometrical picture of the supergravity group given here will provide an adequate basis for the supergravity theory

  2. Supergravity and field space democracy

    International Nuclear Information System (INIS)

    Gayduk, A.V.; Romanov, V.N.; Schwarz, A.S.

    1980-01-01

    Supergravity is presented in which field and space variables are on an equal footing. The action functional of supergravity is characterized as the functional, defined on the space of (4,4)-dimensional submanifolds of complex (4,2)-dimensional superspace, which is invariant with respect to supervolume preserving analytic transformations. It is shown how the Lagrangian of the supergravity in the Ogievetsky-Sokatchev form can be obtained by means of this characterization and describe natural multi-dimensional generalizations of this Lagrangian. These generalizations are based on the notion of perfect action functional

  3. Background metric in supergravity theories

    International Nuclear Information System (INIS)

    Yoneya, T.

    1978-01-01

    In supergravity theories, we investigate the conformal anomaly of the path-integral determinant and the problem of fermion zero modes in the presence of a nontrivial background metric. Except in SO(3) -invariant supergravity, there are nonvanishing conformal anomalies. As a consequence, amplitudes around the nontrivial background metric contain unpredictable arbitrariness. The fermion zero modes which are explicitly constructed for the Euclidean Schwarzschild metric are interpreted as an indication of the supersymmetric multiplet structure of a black hole. The degree of degeneracy of a black hole is 2/sup 4n/ in SO(n) supergravity

  4. Supergravity field theories and the art of constructing them

    International Nuclear Information System (INIS)

    Freedman, D.Z.

    1977-01-01

    The review of supergravity field theories includes global supersymmetry, supergravity, extended supergravity, minimal gauge coupling for spin-3/2 fields, and the general strategy of supergravity constructions. 39 references

  5. Supersymmetry, supergravity and particle physics

    International Nuclear Information System (INIS)

    Nilles, H.P.

    1984-01-01

    We give a short introduction to N=1 supersymmetry and supergravity and review the attempts to construct models in which the breakdown scale of the weak interactions is related to supersymmetry breaking. (orig.)

  6. R{sup 2} supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Ferrara, Sergio [Physics Department, Theory Unit, CERN,CH 1211, Geneva 23 (Switzerland); INFN - Laboratori Nazionali di Frascati,Via Enrico Fermi 40, I-00044 Frascati (Italy); Department of Physics and Astronomy, University of California,Los Angeles, CA 90095-1547 (United States); Kehagias, Alex [Physics Division, National Technical University of Athens,15780 Zografou, Athens (Greece); Porrati, Massimo [Physics Department, Theory Unit, CERN,CH 1211, Geneva 23 (Switzerland); CCPP, Department of Physics,NYU 4 Washington Pl. New York NY 10003 (United States)

    2015-08-03

    We formulate R{sup 2} pure supergravity as a scale invariant theory built only in terms of superfields describing the geometry of curved superspace. The standard supergravity duals are obtained in both “old' and “new' minimal formulations of auxiliary fields. These theories have massless fields in de Sitter space as they do in their non supersymmetric counterpart. Remarkably, the dual theory of R{sup 2} supergravity in the new minimal formulation is an extension of the Freedman model, describing a massless gauge field and a massless chiral multiplet in de Sitter space, with inverse radius proportional to the Fayet-Iliopoulos term. This model can be interpreted as the “de-Higgsed' phase of the dual companion theory of R+R{sup 2} supergravity.

  7. Tribrid Inflation in Supergravity

    International Nuclear Information System (INIS)

    Antusch, Stefan; Dutta, Koushik; Kostka, Philipp M.

    2010-01-01

    We propose a novel class of F-term hybrid inflation models in supergravity (SUGRA) where the η-problem is resolved using either a Heisenberg symmetry or a shift symmetry of the Kaehler potential. In addition to the inflaton and the waterfall field, this class (referred to as tribrid inflation) contains a third 'driving' field which contributes the large vacuum energy during inflation by its F-term. In contrast to the 'standard' hybrid scenario, it has several attractive features due to the property of vanishing inflationary superpotential (W inf = 0) during inflation. While the symmetries of the Kaehler potential ensure a flat inflaton potential at tree-level, quantum corrections induced by symmetry breaking terms in the superpotential generate a slope of the potential and lead to a spectral tilt consistent with recent WMAP observations.

  8. Tribrid Inflation in Supergravity

    Science.gov (United States)

    Antusch, Stefan; Dutta, Koushik; Kostka, Philipp M.

    We propose a novel class of F-term hybrid inflation models in supergravity (SUGRA) where the η-problem is resolved using either a Heisenberg symmetry or a shift symmetry of the Kähler potential. In addition to the inflaton and the waterfall field, this class (referred to as tribrid inflation) contains a third "driving" field which contributes the large vacuum energy during inflation by its F-term. In contrast to the "standard" hybrid scenario, it has several attractive features due to the property of vanishing inflationary superpotential (Winf = 0) during inflation. Quantum corrections induced by symmetry breaking terms in the superpotential generate a slope of the potential and lead to a spectral tilt consistent with recent WMAP observations.

  9. The integral form of supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Castellani, L. [Dipartimento di Scienze e Innovazione Tecnologica, Università del Piemonte Orientale,Viale T. Michel, 11, 15121 Alessandria (Italy); INFN - Sezione di Torino,via P. Giuria 1, 10125 Torino (Italy); Catenacci, R. [Dipartimento di Scienze e Innovazione Tecnologica, Università del Piemonte Orientale,Viale T. Michel, 11, 15121 Alessandria (Italy); Gruppo Nazionale di Fisica Matematica, INdAM,P.le Aldo Moro 5, 00185 Roma (Italy); Grassi, P.A. [Dipartimento di Scienze e Innovazione Tecnologica, Università del Piemonte Orientale,Viale T. Michel, 11, 15121 Alessandria (Italy); INFN - Sezione di Torino,via P. Giuria 1, 10125 Torino (Italy)

    2016-10-11

    By using integral forms we derive the superspace action of D=3,N=1 supergravity as an integral on a supermanifold. The construction is based on target space picture changing operators, here playing the rôle of Poincaré duals to the lower-dimensional spacetime surfaces embedded into the supermanifold. We show how the group geometrical action based on the group manifold approach interpolates between the superspace and the component supergravity actions, thus providing another proof of their equivalence.

  10. IIA/B, Wound and Wrapped

    International Nuclear Information System (INIS)

    Danielsson, Ulf H.; Guijosa, Alberto; Kruczenski, Martin

    2000-01-01

    We examine the T-duality relation between 1+1 NCOS and the DLCQ limit of type IIA string theory. We show that, as long as there is a compact dimension, one can meaningfully define an 'NCOS' limit of IIB/A string theory even in the absence of D-branes (and even if there is no B-field). This yields a theory of closed strings with strictly positive winding, which is T-dual to DLCQ IIA/B without any D-branes. We call this the Type IIB/A Wound String Theory. The existence of decoupled sectors can be seen directly from the energy spectrum, and mirrors that of the DLCQ theory. It becomes clear then that all of the different p+1 NCOS theories are simply different states of this single Wound IIA/B theory which contain D-branes. We study some of the properties of this theory. In particular, we show that upon toroidal compactification, Wound string theory is U-dual to various Wrapped Brane theories which contain OM theory and the ODp theories as special states. (author)

  11. I in generalized supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Araujo, T.; O Colgain, E. [Asia Pacific Center for Theoretical Physics, Pohang (Korea, Republic of); Sakamoto, J.; Yoshida, K. [Kyoto University, Department of Physics, Kyoto (Japan); Sheikh-Jabbari, M.M. [Institute for Research in Fundamental Sciences (IPM), School of Physics, Tehran (Iran, Islamic Republic of)

    2017-11-15

    We showed in previous work that for homogeneous Yang-Baxter (YB) deformations of AdS{sub 5} x S{sup 5} the open string metric and coupling and as a result the closed string density e{sup -2Φ}√(g) remain undeformed. In this work, in addition to extending these results to the deformation associated with the modified CYBE or η-deformation, we identify the Page forms as the open string counterpart for RR fields and demonstrate case by case that the non-zero Page forms remain invariant under YB deformations. We give a physical meaning to the Killing vector I of generalized supergravity and show for all YB deformations: (1) I appears as a current for the center of mass motion on the worldvolume of a D-brane probing the background, (2) I is equal to the divergence of the noncommutativity parameter, (3) I exhibits ''holographic'' behavior where the radial component of I vanishes at the AdS boundary and (4) in pure spinor formalism I is related to a certain state in the BRST cohomology. (orig.)

  12. Scale invariant Volkov–Akulov supergravity

    Directory of Open Access Journals (Sweden)

    S. Ferrara

    2015-10-01

    Full Text Available A scale invariant goldstino theory coupled to supergravity is obtained as a standard supergravity dual of a rigidly scale-invariant higher-curvature supergravity with a nilpotent chiral scalar curvature. The bosonic part of this theory describes a massless scalaron and a massive axion in a de Sitter Universe.

  13. Scale invariant Volkov–Akulov supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Ferrara, S., E-mail: sergio.ferrara@cern.ch [Th-Ph Department, CERN, CH-1211 Geneva 23 (Switzerland); INFN – Laboratori Nazionali di Frascati, Via Enrico Fermi 40, 00044 Frascati (Italy); Department of Physics and Astronomy, University of California, Los Angeles, CA 90095-1547 (United States); Porrati, M., E-mail: mp9@nyu.edu [Th-Ph Department, CERN, CH-1211 Geneva 23 (Switzerland); CCPP, Department of Physics, NYU, 4 Washington Pl., New York, NY 10003 (United States); Sagnotti, A., E-mail: sagnotti@sns.it [Th-Ph Department, CERN, CH-1211 Geneva 23 (Switzerland); Scuola Normale Superiore and INFN, Piazza dei Cavalieri 7, 56126 Pisa (Italy)

    2015-10-07

    A scale invariant goldstino theory coupled to supergravity is obtained as a standard supergravity dual of a rigidly scale-invariant higher-curvature supergravity with a nilpotent chiral scalar curvature. The bosonic part of this theory describes a massless scalaron and a massive axion in a de Sitter Universe.

  14. An N=2 gauge theory and its supergravity dual

    CERN Document Server

    Brandhuber, A

    2000-01-01

    We study flows on the scalar manifold of N=8 gauged supergravity in five dimensions which are dual to certain mass deformations of N=4 super Yang-Mill theory. In particular, we consider a perturbation of the gauge theory by a mass term for the adjoint hyper-multiplet, giving rise to an N=2 theory. The exact solution of the 5-dim gauged supergravity equations of motion is found and the metric is uplifted to a ten-dimensional background of type-IIB supergravity. Using these geometric data and the AdS/CFT correspondence we analyze the spectra of certain operators as well as Wilson loops on the dual gauge theory side. The physical flows are parametrized by a single non-positive constant and describe part of the Coulomb branch of the N=2 theory at strong coupling.

  15. Symmetries of supergravity black holes

    International Nuclear Information System (INIS)

    Chow, David D K

    2010-01-01

    We investigate Killing tensors for various black hole solutions of supergravity theories. Rotating black holes of an ungauged theory, toroidally compactified heterotic supergravity, with NUT parameters and two U(1) gauge fields are constructed. If both charges are set equal, then the solutions simplify, and then there are concise expressions for rank-2 conformal Killing-Staeckel tensors. These are induced by rank-2 Killing-Staeckel tensors of a conformally related metric that possesses a separability structure. We directly verify the separation of the Hamilton-Jacobi equation on this conformally related metric and of the null Hamilton-Jacobi and massless Klein-Gordon equations on the 'physical' metric. Similar results are found for more general solutions; we mainly focus on those with certain charge combinations equal in gauged supergravity but also consider some other solutions.

  16. Studies in gravity and supergravity

    International Nuclear Information System (INIS)

    Castellani, L.

    1981-01-01

    The canonical treatment for theories with local gauge invariances is reviewed and an algorithm for the construction of all the gauge generators is found. This algorithm is then applied to Yang-Mills theories and to (metric) gravity. The first part of the work is concluded with a complete treatment of hamiltonian first order tetrad gravity. In the second part, the geometrical aspects of (super)gravity theories are concentrated on. After an interlude with path integrals in curved space (equivalence is shown with canonical quantization), N = 2 supergravity in superspace, and conformal supergravity in the group manifold scenario are studied. A progress report is added, regarding a study on higher divergences in quantum field theory

  17. C-deformation of supergravity

    International Nuclear Information System (INIS)

    Hatanaka, Tomoya; Ketov, Sergei V

    2006-01-01

    A four-dimensional supergravity toy model in an arbitrary self-dual gravi-photon background is constructed in Euclidean space, by freezing out the gravi-photon field strength in the standard N = (1, 1) extended supergravity with two non-chiral gravitini. Our model has local N = (1/2, 0) supersymmetry. Consistency of the model requires the background gravi-photon field strength to be equal to the self-dual (bilinear) anti-chiral gravitino condensate. (letter to the editor)

  18. A worldsheet theory for supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Adamo, Tim; Casali, Eduardo; Skinner, David [Department of Applied Mathematics & Theoretical Physics, University of Cambridge,Wilberforce Road, Cambridge CB3 0WA (United Kingdom)

    2015-02-18

    We present a worldsheet theory that describes maps into a curved target space equipped with a B-field and dilaton. The conditions for the theory to be consistent at the quantum level can be computed exactly, and are that the target space fields obey the nonlinear d=10 supergravity equations of motion, with no higher curvature terms. The path integral is constrained to obey a generalization of the scattering equations to curved space. Remarkably, the supergravity field equations emerge as quantum corrections to these curved space scattering equations.

  19. N-flation in supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Das, Kumar, E-mail: kumar.das@saha.ac.in; Dutta, Koushik, E-mail: koushik.dutta@saha.ac.in

    2014-11-10

    We have constructed a large field N-flation model in the supergravity framework. In this simple set-up, N fields collectively drive inflation where each field traverses sub-Planckian field values. This has been realised with a generalisation of the single-field chaotic inflation in supergravity. Interestingly, despite the presence of the field interactions, the dynamics can be described in terms of an effective single field. The observable predictions of our model, i.e., tensor-to-scalar ratio r and scalar spectral index n{sub s}, are akin to the chaotic inflation.

  20. Introduction to supersymmetry and supergravity

    International Nuclear Information System (INIS)

    West, P.

    1990-01-01

    This book discusses two-dimensional supersymmetry algebras, and their irreducible representations as well as rigid and local (supergravity) theories of supersymmetry both in x-space and superspace. These theories include the actions for the superstring and the heterotic string. A discussion on superconformal algebras in two dimensions and an account of super operator product expansion are included

  1. Geometrical interpretation of extended supergravity

    International Nuclear Information System (INIS)

    Townsend, P.K.; Nieuwenhuizen, P.van

    1977-01-01

    SO 2 extended supergravity is shown to be a geometrical theory, whose underlying gauge group is OSp(4,2). The couplings which gauge the SO 2 symmetry as well as the accompanying cosmological and masslike terms are directly obtained, and the usual SO 2 model is obtained after a Wigner-Inoenue group contraction. (Auth.)

  2. Problems in unification and supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Farrar, G.; Henyey, F. (eds.)

    1984-01-01

    Problems in unification of the various gauge groups, quantum gravity, supersymmetry and supergravity, compact dimensions of space-time, and conditions at the beginning of the universe are discussed. Separate entries were prepared for the data base for the 15 papers presented. (WHK)

  3. Problems in unification and supergravity

    International Nuclear Information System (INIS)

    Farrar, G.; Henyey, F.

    1984-01-01

    Problems in unification of the various gauge groups, quantum gravity, supersymmetry and supergravity, compact dimensions of space-time, and conditions at the beginning of the universe are discussed. Separate entries were prepared for the data base for the 15 papers presented

  4. Geometric construction of extended supergravity

    International Nuclear Information System (INIS)

    Kostelecky, V.A.

    1982-01-01

    This work describes the explict construction of the locally SO(4)-invariant, on-shell de Sitter supergravity. First, aspects of classical differential geometry used in the construction of local gauge theories are reviewed. Emphasis is placed on fiber bundles and their uses in Yang-Mills and Einstein theories. Next, the extension of the formalism to differential supergeometry is outlined. Applications to extended supergravities are discussed. Finally, the O(4) deSitter supergravity is obtained by considering a bundle of frames constructed using the orthosymplectic superalgebra osp(4/4). The structure group of this bundle is Sl(2C) x SO(4) and the tangent space to the base supermanifold is homeomorphic to the coset osp(4/4)/sl(2C) x so(4). Constraints taken into the Bianchi identifies yield a realization of the superalgebra in the function space of connections, vielbeins, curvatures and torsions of the bundle. Auxiliary fields, transformation laws and equations of motion are determined. Consistency of the realization is verified, proving closure of the algebra. The associated Poincare supergravity is obtained by a contraction

  5. Cartan's geometrical structure of supergravity

    International Nuclear Information System (INIS)

    Baaklini, N.S.

    1977-06-01

    The geometrical partnership of the vierbein and the spin-3/2 field in the structure of the supergravity Lagrangian is emphasized. Both fields are introduced as component of the same matrix differential form. The only local symmetry of the theory is SL(2,C)

  6. Analysis of tanshinone IIA induced cellular apoptosis in leukemia cells by genome-wide expression profiling

    Directory of Open Access Journals (Sweden)

    Liu Chang

    2012-01-01

    Full Text Available Abstract Background Tanshinone IIA (Tan IIA is a diterpene quinone extracted from the root of Salvia miltiorrhiza, a Chinese traditional herb. Although previous studies have reported the anti-tumor effects of Tan IIA on various human cancer cells, the underlying mechanisms are not clear. The current study was undertaken to investigate the molecular mechanisms of Tan IIA's apoptotic effects on leukemia cells in vitro. Methods The cytotoxicity of Tan IIA on different types of leukemia cell lines was evaluated by the 3-[4,5-dimethylthiazol-2,5]-diphenyl tetrazolium bromide (MTT assay on cells treated without or with Tan IIA at different concentrations for different time periods. Cellular apoptosis progression with and without Tan IIA treatment was analyzed by Annexin V and Caspase 3 assays. Gene expression profiling was used to identify the genes regulated after Tan IIA treatment and those differentially expressed among the five cell lines. Confirmation of these expression regulations was carried out using real-time quantitative PCR and ELISA. The antagonizing effect of a PXR inhibitor L-SFN on Tan IIA treatment was tested using Colony Forming Unit Assay. Results Our results revealed that Tan IIA had different cytotoxic activities on five types of leukemia cells, with the highest toxicity on U-937 cells. Tan IIA inhibited the growth of U-937 cells in a time- and dose-dependent manner. Annexin V and Caspase-3 assays showed that Tan IIA induced apoptosis in U-937 cells. Using gene expression profiling, 366 genes were found to be significantly regulated after Tan IIA treatment and differentially expressed among the five cell lines. Among these genes, CCL2 was highly expressed in untreated U-937 cells and down-regulated significantly after Tan IIA treatment in a dose-dependent manner. RT-qPCR analyses validated the expression regulation of 80% of genes. Addition of L- sulforaphane (L-SFN, an inhibitor of Pregnane × receptor (PXR significantly

  7. Tanshinone IIA stimulates erythrocyte phosphatidylserine exposure

    NARCIS (Netherlands)

    Zelenak, C.; Pasham, V.; Jilani, K.; Tripodi, P.M.; Rosaclerio, L.; Pathare, G.T.; Lupescu, A.; Faggio, C.; Qadri, S.M.; Lang, F.

    2012-01-01

    Tanshinone IIA, an antimicrobial, antioxidant, antianaphylactic, antifibrotic, vasodilating, antiatherosclerotic, organo-protective and antineoplastic component from the rhizome of Salvia miltiorrhiza, is known to trigger apoptosis of tumor cells. Tanshinone IIA is effective in part through

  8. Asymptomatic freedom in renormalisable gravity and supergravity

    International Nuclear Information System (INIS)

    Fradkin, E.S.; Tseytlin, A.A.

    1984-01-01

    This chapter demonstrates that renormalizable supergravity, which is a superextension of renormalizable quantum gravity, can be the basis for a natural ''induced supergravity'' theory. A perturbatively operational unified theory is needed for a description of the early stages of the Universe, and renormalizable quantum gravity is well suited for unification with the renormalizable Grand Unified Models of matter. Topics considered include one-loop counter-terms and renormalization group (RG) equations for pure renormalizable gravity; the consequences of asymptotic freedom; the inclusion of matter; conformal supergravities; and renormalizable supergravity models. It is concluded that the presented lagrangian, which contains a locally superconformal extension of the Yang-Mills and massless spinor lagrangians and the conformal supergravity term, shows that conformal supergravity may play an important role in a fundamental theory

  9. On maximal massive 3D supergravity

    OpenAIRE

    Bergshoeff , Eric A; Hohm , Olaf; Rosseel , Jan; Townsend , Paul K

    2010-01-01

    ABSTRACT We construct, at the linearized level, the three-dimensional (3D) N = 4 supersymmetric " general massive supergravity " and the maximally supersymmetric N = 8 " new massive supergravity ". We also construct the maximally supersymmetric linearized N = 7 topologically massive supergravity, although we expect N = 6 to be maximal at the non-linear level. (Bergshoeff, Eric A) (Hohm, Olaf) (Rosseel, Jan) P.K.Townsend@da...

  10. Spontaneous symmetry breaking in N=3 supergravity

    International Nuclear Information System (INIS)

    Zinov'ev, Yu.M.

    1986-01-01

    The possibility of the spontaneous symmetry breaking without a cosmological term in N=3 supergravity is investigated. A new, dual version of N=3 supergravity - U(3)-supergravity is constructed. Such a theory is shown to admit a spontaneous supersymmetry breaking without a cosmological term and with three arbitrary scales, including partial super-Higgs effect N=3 → N=2 and N=3 → N=1

  11. Coupling brane fields to bulk supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Parameswaran, Susha L. [Uppsala Univ. (Sweden). Theoretical Physics; Schmidt, Jonas [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2010-12-15

    In this note we present a simple, general prescription for coupling brane localized fields to bulk supergravity. We illustrate the procedure by considering 6D N=2 bulk supergravity on a 2D orbifold, with brane fields localized at the fixed points. The resulting action enjoys the full 6D N=2 symmetries in the bulk, and those of 4D N=1 supergravity at the brane positions. (orig.)

  12. Unconstrained multiplet in N=2 conformal supergravity

    International Nuclear Information System (INIS)

    Hayashi, Masahito; Uehara, Shozo.

    1985-02-01

    An unconstrained (general) multiplet was studied in N = 2 conformal supergravity. Transformation law, embedding formula and multiplication rule are explicitly presented at the linearized level. (author)

  13. Supersymmetry and supergravity: Phenomenology and grand unification

    International Nuclear Information System (INIS)

    Arnowitt, R.; Nath, P.

    1993-01-01

    A survey is given of supersymmetry and supergravity and their phenomenology. Some of the topics discussed are the basic ideas of global supersymmetry, the minimal supersymmetric Standard Model (MSSM) and its phenomenology, the basic ideas of local supersymmetry (supergravity), grand unification, supersymmetry breaking in supergravity grand unified models, radiative breaking of SU(2) x U(1), proton decay, cosmological constraints, and predictions of supergravity grand unified models. While the number of detailed derivations are necessarily limited, a sufficient number of results are given so that a reader can get a working knowledge of this field

  14. Composite gravity and composite supergravity

    International Nuclear Information System (INIS)

    Lukierski, J.

    1982-09-01

    It is known that the composite YM H-gauge theory can be constructed from σ-fields taking values in a symmetric Riemannian space G/H. We extend such a framework to graded σ-fields taking values in supercosets. We show that from supercoset σ-fields one can construct composite gravity, and from supercoset σ-superfields the composite supergravity models. (author)

  15. Potentials in N=2 supergravity

    International Nuclear Information System (INIS)

    Zinov'ev, Yu.M.

    1985-01-01

    The potentials and Yukava interactions, that arise while introducing a gauge interaction of vector and scalar multiplets in N=2 supergravity are presented, in this the gauge group may be either compact or noncompact. The scalar multiplets geometry corresponds to nonlinear σ, models of the form Sp(2,2n)/Sp(2)xSp(2n), SU(2,n)/SU(2)SU(n)xU(1) and O(4,n)/O(4)xO(n)

  16. Long range supergravity coupling strengths

    International Nuclear Information System (INIS)

    Kenyon, I.R.

    1991-01-01

    A limit of 2x10 -13 has recently been deduced for the fractional difference between the gravitational masses of the K 0 and anti K 0 mesons. This limit is applied here to put stringent limits on the strengths of the long range vector-scalar gravitational couplings envisaged in supergravity theories. A weaker limit is inferred from the general relativistic fit to the precession of the orbit of the pulsar PSR1913+16. (orig.)

  17. The supergravity fields for a D-brane with a travelling wave from string amplitudes

    International Nuclear Information System (INIS)

    Black, William; Russo, Rodolfo; Turton, David

    2010-01-01

    We calculate the supergravity fields sourced by a D-brane with a null travelling wave from disk amplitudes in type IIB string theory compactified on T 4 xS 1 . The amplitudes reproduce all the non-trivial features of the previously known two-charge supergravity solutions in the D-brane/momentum duality frame, providing a direct link between the microscopic bound states and their macroscopic descriptions.

  18. Impacts of supersymmetric higher derivative terms on inflation models in supergravity

    International Nuclear Information System (INIS)

    Aoki, Shuntaro; Yamada, Yusuke

    2015-01-01

    We show the effects of supersymmetric higher derivative terms on inflation models in supergravity. The results show that such terms generically modify the effective kinetic coefficient of the inflaton during inflation if the cut off scale of the higher derivative operators is sufficiently small. In such a case, the η-problem in supergravity does not occur, and we find that the effective potential of the inflaton generically becomes a power type potential with a power smaller than two

  19. MYBPH inhibits NM IIA assembly via direct interaction with NMHC IIA and reduces cell motility

    International Nuclear Information System (INIS)

    Hosono, Yasuyuki; Usukura, Jiro; Yamaguchi, Tomoya; Yanagisawa, Kiyoshi; Suzuki, Motoshi; Takahashi, Takashi

    2012-01-01

    Highlights: ► MYBPH inhibits NMHC IIA assembly and cell motility. ► MYBPH interacts to assembly-competent NM IIA. ► MYBPH inhibits RLC and NMHC IIA, independent components of NM IIA. -- Abstract: Actomyosin filament assembly is a critical step in tumor cell migration. We previously found that myosin binding protein H (MYBPH) is directly transactivated by the TTF-1 lineage-survival oncogene in lung adenocarcinomas and inhibits phosphorylation of the myosin regulatory light chain (RLC) of non-muscle myosin IIA (NM IIA) via direct interaction with Rho kinase 1 (ROCK1). Here, we report that MYBPH also directly interacts with an additional molecule, non-muscle myosin heavy chain IIA (NMHC IIA), which was found to occur between MYBPH and the rod portion of NMHC IIA. MYBPH inhibited NMHC IIA assembly and reduced cell motility. Conversely, siMYBPH-induced increased motility was partially, yet significantly, suppressed by blebbistatin, a non-muscle myosin II inhibitor, while more profound effects were attained by combined treatment with siROCK1 and blebbistatin. Electron microscopy observations showed well-ordered paracrystals of NMHC IIA reflecting an assembled state, which were significantly less frequently observed in the presence of MYBPH. Furthermore, an in vitro sedimentation assay showed that a greater amount of NMHC IIA was in an unassembled state in the presence of MYBPH. Interestingly, treatment with a ROCK inhibitor that impairs transition of NM IIA from an assembly-incompetent to assembly-competent state reduced the interaction between MYBPH and NMHC IIA, suggesting that MYBPH has higher affinity to assembly-competent NM IIA. These results suggest that MYBPH inhibits RLC and NMHC IIA, independent components of NM IIA, and negatively regulates actomyosin organization at 2 distinct steps, resulting in firm inhibition of NM IIA assembly.

  20. More gaugings of N=8 supergravity

    International Nuclear Information System (INIS)

    Hull, C.M.

    1984-01-01

    New non-compact gaugings of N = 8 supergravity are constructed. The gauge groups are SO(p,q) (with p + q = 8) and the group contraction of SO(p,q) about SO(p). The SO(4,4) gauging and the corresponding contraction truncate to gauged N = 4 supergravity theories. (orig.)

  1. Experimental limits on antigravity in extended supergravity

    OpenAIRE

    Bellucci, S.; Faraoni, V.

    1995-01-01

    The available tests of the equivalence principle constrain the mass of the Higgs-like boson appearing in extended supergravity theories. We determine the constraints imposed by the present and future high precision experiments on the antigravity fields arising from $N=2,8$ supergravity.

  2. Regulation of myosin IIA and filamentous actin during insulin-stimulated glucose uptake in 3T3-L1 adipocytes

    International Nuclear Information System (INIS)

    Stall, Richard; Ramos, Joseph; Kent Fulcher, F.; Patel, Yashomati M.

    2014-01-01

    Insulin stimulated glucose uptake requires the colocalization of myosin IIA (MyoIIA) and the insulin-responsive glucose transporter 4 (GLUT4) at the plasma membrane for proper GLUT4 fusion. MyoIIA facilitates filamentous actin (F-actin) reorganization in various cell types. In adipocytes F-actin reorganization is required for insulin-stimulated glucose uptake. What is not known is whether MyoIIA interacts with F-actin to regulate insulin-induced GLUT4 fusion at the plasma membrane. To elucidate the relationship between MyoIIA and F-actin, we examined the colocalization of MyoIIA and F-actin at the plasma membrane upon insulin stimulation as well as the regulation of this interaction. Our findings demonstrated that MyoIIA and F-actin colocalized at the site of GLUT4 fusion with the plasma membrane upon insulin stimulation. Furthermore, inhibition of MyoII with blebbistatin impaired F-actin localization at the plasma membrane. Next we examined the regulatory role of calcium in MyoIIA-F-actin colocalization. Reduced calcium or calmodulin levels decreased colocalization of MyoIIA and F-actin at the plasma membrane. While calcium alone can translocate MyoIIA it did not stimulate F-actin accumulation at the plasma membrane. Taken together, we established that while MyoIIA activity is required for F-actin localization at the plasma membrane, it alone is insufficient to localize F-actin to the plasma membrane. - Highlights: • Insulin induces colocalization of MyoIIA and F-actin at the cortex in adipocytes. • MyoIIA is necessary but not sufficient to localize F-actin at the cell cortex. • MyoIIA-F-actin colocalization is regulated by calcium and calmodulin

  3. The Wasteland of Random Supergravities

    OpenAIRE

    Marsh, David; McAllister, Liam; Wrase, Timm

    2011-01-01

    We show that in a general \\cal{N} = 1 supergravity with N \\gg 1 scalar fields, an exponentially small fraction of the de Sitter critical points are metastable vacua. Taking the superpotential and Kahler potential to be random functions, we construct a random matrix model for the Hessian matrix, which is well-approximated by the sum of a Wigner matrix and two Wishart matrices. We compute the eigenvalue spectrum analytically from the free convolution of the constituent spectra and find that in ...

  4. Inflaton decay through supergravity effects

    International Nuclear Information System (INIS)

    Endo, M.; Takahashi, F.; Kawasaki, M.; Yanagida, T.T.; Tokyo Univ.

    2006-07-01

    We point out that supergravity effects enable the inflaton to decay into all matter fields, including the visible and the supersymmetry breaking sectors, once the inflaton acquires a non-vanishing vacuum expectation value. The new decay processes have great impacts on cosmology; the reheating temperature is bounded below; the gravitinos are produced by the inflaton decay in a broad class of the dynamical supersymmetry breaking models. We derive the bounds on the inflaton mass and the vacuum expectation value, which severely constrain high-scale inflations such as the hybrid and chaotic inflation models. (orig.)

  5. Classical solutions and extended supergravity

    International Nuclear Information System (INIS)

    de Alfaro, V.; Fubini, S.; Furlan, G.

    1980-03-01

    The existence and properties of classical solutions for gravity coupled to matter fields have been investigated previously with the limitation to conformally flat solutions. In the search for a guiding criterion to determine the form of the coupling among the fields, one is led to consider supersymmetric theories, and the question arises whether classical solutions persist in these models. It is found that a discrepancy persists between supergravity and standard meron solutions. Owing to the appearance of the scalar field, a new set of meron solutions exists for particular Lagrangian models. In conclusion, the form of solutions in Minkowski space is discussed

  6. Supersymmetric solutions of minimal gauged supergravity in five dimensions

    International Nuclear Information System (INIS)

    Gauntlett, Jerome P.; Gutowski, Jan B.

    2003-01-01

    All purely bosonic supersymmetric solutions of minimal gauged supergravity in five dimensions are classified. The solutions fall into two classes depending on whether the Killing vector constructed from the Killing spinor is timelike or null. When it is timelike, the solutions are determined by a four-dimensional Kaehler base manifold, up to an antiholomorphic function, are necessarily not static, and generically preserve 1/2 of the supersymmetry. When it is null we provide a precise prescription for constructing the solutions and we show that they generically preserve 1/4 of the supersymmetry. We show that five-dimensional anti-de Sitter space (AdS 5 ) is the unique maximally supersymmetric configuration. The formalism is used to construct some new solutions, including a nonsingular deformation of AdS 5 , which can be uplifted to obtain new solutions of type IIB supergravity

  7. Asymptotic freedom in extended conformal supergravities

    International Nuclear Information System (INIS)

    Fradkin, E.S.; Tseytlin, A.A.

    1982-01-01

    We present the calculation of the one-loop β-function in extended conformal supergravities. N = 1, 2, 3 theories (free or coupled to the Einstein supergravities) are found to the asymptotically free (like the N = 0 Weyl theory) while the N = 4 theory becomes finite under some plausible hypothesis. The results support the possibility to solve the problem of ghosts in these theories. The obtained sequence of SU(N) β-functions appears to be in remarkable correspondence with that for gauged O(N) supergravity theories. (orig.)

  8. Tanshinone IIA ameliorates dextran sulfate sodium-induced inflammatory bowel disease via the pregnane X receptor

    Science.gov (United States)

    Zhang, Xianxie; Wang, Yuguang; Ma, Zengchun; Liang, Qiande; Tang, Xianglin; Hu, Donghua; Tan, Hongling; Xiao, Chengrong; Gao, Yue

    2015-01-01

    Tanshinone IIA (Tan IIA) (C19H18O3) is one of the major active lipophilic components in a conventional Chinese medicine called danshen, and it has long been used in the People’s Republic of China and other neighboring countries to treat patients suffering from inflammatory bowel disease (IBD). Previous experiments by many teams determined which mechanism of Tan IIA is relevant to the treatment of IBD associated with inflammation and the pregnane X receptor (PXR). The current study demonstrated that Tan IIA is an efficacious PXR agonist and its ability to induce CYP3A4 mRNA and protein expression was mediated by the transactivation of PXR, a known target of abrogating inflammation in IBD. Clinical symptoms in mice and histological assessment data suggested that administration of Tan IIA in mice demonstrated significant protection and showed that in DSS-induced IBD it acts in a concentration-dependent manner. PXR-silenced mice treated with Tan IIA demonstrated low protection against DSS-induced mouse IBD and exacerbated the severity of IBD compared with wild-type mice; PXR-silenced mice demonstrated the necessity for PXR in Tan IIA-mediated upregulation of xenobiotic metabolism genes. The IBD treatment effects of Tan IIA are partially due to PXR-mediated upregulation of xenobiotic metabolism and downregulation of inflammatory mediators. The novel findings reported here may contribute to the effective utilization of Tan IIA and its derivatives as a PXR ligand in the treatment of human IBD. This suggests that Tan IIA may have considerable clinical utility. PMID:26674743

  9. Septin 7 reduces nonmuscle myosin IIA activity in the SNAP23 complex and hinders GLUT4 storage vesicle docking and fusion

    Energy Technology Data Exchange (ETDEWEB)

    Wasik, Anita A.; Dumont, Vincent [Department of Pathology, University of Helsinki, 00014 Helsinki (Finland); Tienari, Jukka [Department of Pathology, University of Helsinki and Helsinki University Hospital, 00290 Helsinki, 05850 Hyvinkää (Finland); Nyman, Tuula A. [Institute of Biotechnology, University of Helsinki, 00014 Helsinki (Finland); Fogarty, Christopher L.; Forsblom, Carol; Lehto, Markku [Folkhälsan Institute of Genetics, Folkhälsan Research Center, 00290 Helsinki (Finland); Abdominal Center Nephrology, University of Helsinki and Helsinki University Hospital, 000290 Helsinki (Finland); Diabetes& Obesity Research Program, Research Program´s Unit, 00014 University of Helsinki (Finland); Lehtonen, Eero [Department of Pathology, University of Helsinki, 00014 Helsinki (Finland); Laboratory Animal Centre, University of Helsinki, 00014 Helsinki (Finland); Groop, Per-Henrik [Folkhälsan Institute of Genetics, Folkhälsan Research Center, 00290 Helsinki (Finland); Abdominal Center Nephrology, University of Helsinki and Helsinki University Hospital, 000290 Helsinki (Finland); Diabetes& Obesity Research Program, Research Program´s Unit, 00014 University of Helsinki (Finland); Baker IDI Heart & Diabetes Institute, 3004 Melbourne (Australia); Lehtonen, Sanna, E-mail: sanna.h.lehtonen@helsinki.fi [Department of Pathology, University of Helsinki, 00014 Helsinki (Finland)

    2017-01-15

    Glomerular epithelial cells, podocytes, are insulin responsive and can develop insulin resistance. Here, we demonstrate that the small GTPase septin 7 forms a complex with nonmuscle myosin heavy chain IIA (NMHC-IIA; encoded by MYH9), a component of the nonmuscle myosin IIA (NM-IIA) hexameric complex. We observed that knockdown of NMHC-IIA decreases insulin-stimulated glucose uptake into podocytes. Both septin 7 and NM-IIA associate with SNAP23, a SNARE protein involved in GLUT4 storage vesicle (GSV) docking and fusion with the plasma membrane. We observed that insulin decreases the level of septin 7 and increases the activity of NM-IIA in the SNAP23 complex, as visualized by increased phosphorylation of myosin regulatory light chain. Also knockdown of septin 7 increases the activity of NM-IIA in the complex. The activity of NM-IIA is increased in diabetic rat glomeruli and cultured human podocytes exposed to macroalbuminuric sera from patients with type 1 diabetes. Collectively, the data suggest that the activity of NM-IIA in the SNAP23 complex plays a key role in insulin-stimulated glucose uptake into podocytes. Furthermore, we observed that septin 7 reduces the activity of NM-IIA in the SNAP23 complex and thereby hinders GSV docking and fusion with the plasma membrane. - Highlights: • Septin 7, nonmuscle myosin heavy chain IIA (NMHC-IIA) and SNAP23 form a complex. • Knockdown of septin 7 increases NM-IIA activity in the SNAP23 complex. • Insulin decreases septin 7 level and increases NM-IIA activity in the SNAP23 complex. • Septin 7 hinders GSV docking/fusion by reducing NM-IIA activity in the SNAP23 complex.

  10. Septin 7 reduces nonmuscle myosin IIA activity in the SNAP23 complex and hinders GLUT4 storage vesicle docking and fusion

    International Nuclear Information System (INIS)

    Wasik, Anita A.; Dumont, Vincent; Tienari, Jukka; Nyman, Tuula A.; Fogarty, Christopher L.; Forsblom, Carol; Lehto, Markku; Lehtonen, Eero; Groop, Per-Henrik; Lehtonen, Sanna

    2017-01-01

    Glomerular epithelial cells, podocytes, are insulin responsive and can develop insulin resistance. Here, we demonstrate that the small GTPase septin 7 forms a complex with nonmuscle myosin heavy chain IIA (NMHC-IIA; encoded by MYH9), a component of the nonmuscle myosin IIA (NM-IIA) hexameric complex. We observed that knockdown of NMHC-IIA decreases insulin-stimulated glucose uptake into podocytes. Both septin 7 and NM-IIA associate with SNAP23, a SNARE protein involved in GLUT4 storage vesicle (GSV) docking and fusion with the plasma membrane. We observed that insulin decreases the level of septin 7 and increases the activity of NM-IIA in the SNAP23 complex, as visualized by increased phosphorylation of myosin regulatory light chain. Also knockdown of septin 7 increases the activity of NM-IIA in the complex. The activity of NM-IIA is increased in diabetic rat glomeruli and cultured human podocytes exposed to macroalbuminuric sera from patients with type 1 diabetes. Collectively, the data suggest that the activity of NM-IIA in the SNAP23 complex plays a key role in insulin-stimulated glucose uptake into podocytes. Furthermore, we observed that septin 7 reduces the activity of NM-IIA in the SNAP23 complex and thereby hinders GSV docking and fusion with the plasma membrane. - Highlights: • Septin 7, nonmuscle myosin heavy chain IIA (NMHC-IIA) and SNAP23 form a complex. • Knockdown of septin 7 increases NM-IIA activity in the SNAP23 complex. • Insulin decreases septin 7 level and increases NM-IIA activity in the SNAP23 complex. • Septin 7 hinders GSV docking/fusion by reducing NM-IIA activity in the SNAP23 complex.

  11. A cosmological problem for maximally symmetric supergravity

    International Nuclear Information System (INIS)

    German, G.; Ross, G.G.

    1986-01-01

    Under very general considerations it is shown that inflationary models of the universe based on maximally symmetric supergravity with flat potentials are unable to resolve the cosmological energy density (Polonyi) problem. (orig.)

  12. Constraining supergravity models from gluino production

    International Nuclear Information System (INIS)

    Barbieri, R.; Gamberini, G.; Giudice, G.F.; Ridolfi, G.

    1988-01-01

    The branching ratios for gluino decays g tilde → qanti qΧ, g tilde → gΧ into a stable undetected neutralino are computed as functions of the relevant parameters of the underlying supergravity theory. A simple way of constraining supergravity models from gluino production emerges. The effectiveness of hadronic versus e + e - colliders in the search for supersymmetry can be directly compared. (orig.)

  13. Perturbative and global anomalies in supergravity theories

    International Nuclear Information System (INIS)

    Sezgin, E.

    1986-09-01

    Perturbative and global anomalies in supergravity theories are reviewed. The existence of a matter and gauge coupled supergravity theory in six dimensions with E 6 xE 7 xU(1) symmetry and highly nontrivial anomaly cancellations is emphasised. The possible string origin of this theory is posed as an open problem, study of which may lead to discovery of new ways to construct/compactify heterotic superstrings. (author)

  14. Anti-de Sitter black holes in gauged supergravity. Supergravity flow, thermodynamics and phase transitions

    NARCIS (Netherlands)

    Toldo, C.

    2014-01-01

    This thesis is devoted to the analysis of asymptotically Anti-de Sitter (AdS) black holes arising as solutions of theories of gauged Supergravity in four spacetime dimensions. After a brief recap of the main features of gauged supergravity, the first part of the thesis deals with the explicit

  15. Increased expression and activity of group IIA and X secretory phospholipase A2 in peritumoral versus central colon carcinoma tissue

    DEFF Research Database (Denmark)

    Tribler, Line; Jensen, Lotte T.; Jørgensen, Kent

    2007-01-01

    Secretory phospholipase A2 (sPLA2) type IIA and X was analyzed in tumors from 22 patients with colon adenocarcinomas in order to determine the involvement and activity of sPLA2 in colon cancer. Evaluation of immunoreactive sPLA2 IIA by Western blotting showed a significantly higher level...... in the periphery of the tumors, compared to central tumor regions. Increased levels of sPLA2 IIA protein correlated with a two-fold increase in sPLA2 enzymatic activity in the peripheral regions compared to central regions. Nineteen out of 22 tumors showed high levels of sPLA2 IIA, whereas 7 out of the 22 tumors...... showed sPLA2 type X. These data demonstrate that both sPLA2 type IIA and X are present in human colon cancer and suggest a role for sPLA2 in colon cancer tumor immunology and tumorigenesis....

  16. Supergravity and the quest for a unified theory

    International Nuclear Information System (INIS)

    Ferrara, S.

    1995-01-01

    The foundation of supergravity and research in its subsequent developments is described. Special emphasis is placed on the impact of supergravity on the search for a unified theory of fundamental interactions. (author)

  17. Higher-Derivative Supergravity and Moduli Stabilization

    International Nuclear Information System (INIS)

    Ciupke, David; Westphal, Alexander; Louis, Jan; Hamburg Univ.

    2015-05-01

    We review the ghost-free four-derivative terms for chiral superfields in N=1 supersymmetry and supergravity. These terms induce cubic polynomial equations of motion for the chiral auxiliary fields and correct the scalar potential. We discuss the different solutions and argue that only one of them is consistent with the principles of effective field theory. Special attention is paid to the corrections along flat directions which can be stabilized or destabilized by the higher-derivative terms. We then compute these higher-derivative terms explicitly for the type IIB string compactified on a Calabi-Yau orientifold with fluxes via Kaluza-Klein reducing the (α') 3 R 4 corrections in ten dimensions for the respective N=1 Kaehler moduli sector. We prove that together with flux and the known (α') 3 -corrections the higher-derivative term stabilizes all Calabi-Yau manifolds with positive Euler number, provided the sign of the new correction is negative.

  18. Unified Maxwell-Einstein and Yang-Mills-Einstein supergravity theories in five dimensions

    International Nuclear Information System (INIS)

    Guenaydin, Murat; Zagermann, Marco

    2003-01-01

    Unified N = 2 Maxwell-Einstein supergravity theories (MESGTs) are supergravity theories in which all the vector fields, including the graviphoton, transform in an irreducible representation of a simple global symmetry group of the Lagrangian. As was established long time ago, in five dimensions there exist only four unified Maxwell-Einstein supergravity theories whose target manifolds are symmetric spaces. These theories are defined by the four simple euclidean Jordan algebras of degree three. In this paper, we show that, in addition to these four unified MESGTs with symmetric target spaces, there exist three infinite families of unified MESGTs as well as another exceptional one. These novel unified MESGTs are defined by non-compact (minkowskian) Jordan algebras, and their target spaces are in general neither symmetric nor homogeneous. The members of one of these three infinite families can be gauged in such a way as to obtain an infinite family of unified N = 2 Yang-Mills-Einstein supergravity theories, in which all vector fields transform in the adjoint representation of a simple gauge group of the type SU(N,1). The corresponding gaugings in the other two infinite families lead to Yang-Mills-Einstein supergravity theories coupled to tensor multiplets. (author)

  19. Yang-Mills-Chern-Simons supergravity

    International Nuclear Information System (INIS)

    Lue, H; Pope, C N; Sezgin, E

    2004-01-01

    N = (1, 0) supergravity in six dimensions admits AdS 3 x S 3 as a vacuum solution. We extend our recent results presented in Lue et al (2002 Preprint hep-th/0212323), by obtaining the complete N = 4 Yang-Mills-Chern-Simons supergravity in D = 3, up to quartic fermion terms, by S 3 group manifold reduction of the six-dimensional theory. The SU(2) gauge fields have Yang-Mills kinetic terms as well as topological Chern-Simons mass terms. There is in addition a triplet of matter vectors. After diagonalization, these fields describe two triplets of topologically-massive vector fields of opposite helicities. The model also contains six scalars, described by a GL(3, R)/SO(3) sigma model. It provides the first example of a three-dimensional gauged supergravity that can be obtained by a consistent reduction of string theory or M-theory and that admits AdS 3 as a vacuum solution. There are unusual features in the reduction from six-dimensional supergravity, owing to the self-duality condition on the 3-form field. The structure of the full equations of motion in N = (1, 0) supergravity in D = 6 is also elucidated, and the role of the self-dual field strength as torsion is exhibited

  20. Hidden symmetries in five-dimensional supergravity

    International Nuclear Information System (INIS)

    Poessel, M.

    2003-05-01

    This thesis is concerned with the study of hidden symmetries in supergravity, which play an important role in the present picture of supergravity and string theory. Concretely, the appearance of a hidden G 2(+2) /SO(4) symmetry is studied in the dimensional reduction of d=5, N=2 supergravity to three dimensions - a parallel model to the more famous E 8(+8) /SO(16) case in eleven-dimensional supergravity. Extending previous partial results for the bosonic part, I give a derivation that includes fermionic terms. This sheds new light on the appearance of the local hidden symmetry SO(4) in the reduction, and shows up an unusual feature which follows from an analysis of the R-symmetry associated with N=4 supergravity and of the supersymmetry variations, and which has no parallel in the eleven-dimensional case: The emergence of an additional SO(3) as part of the enhanced local symmetry, invisible in the dimensional reduction of the gravitino, and corresponding to the fact that, of the SO(4) used in the coset model, only the diagonal SO(3) is visible immediately upon dimensional reduction. The uncovering of the hidden symmetries proceeds via the construction of the proper coset gravity in three dimensions, and matching it with the Lagrangian obtained from the reduction. (orig.)

  1. Background harmonic superfields in N=2 supergravity

    International Nuclear Information System (INIS)

    Zupnik, B.M.

    1998-01-01

    A modification of the harmonic superfield formalism in D=4, N=2 supergravity using a subsidiary condition of covariance under the background supersymmetry with a central charge (B-covariance) is considered. Conservation of analyticity together with the B-covariance leads to the appearance of linear gravitational superfields. Analytic prepotentials arise in a decomposition of the background linear superfields in terms of spinor coordinates and transform in a nonstandard way under the background supersymmetry. The linear gravitational superfields can be written via spinor derivatives of nonanalytic spinor prepotentials. The perturbative expansion of supergravity action in terms of the B-covariant superfields and the corresponding version of the differential-geometric formalism are considered. We discuss the dual harmonic representation of the linearized extended supergravity, which corresponds to the dynamical condition of Grassmann analyticity

  2. High energy scattering in gravity and supergravity

    CERN Document Server

    Giddings, Steven B; Andersen, Jeppe R

    2010-01-01

    We investigate features of perturbative gravity and supergravity by studying scattering in the ultraplanckian limit, and sharpen arguments that the dynamics is governed by long-distance physics. A simple example capturing aspects of the eikonal resummation suggests why short distance phenomena and in particular divergences or nonrenormalizability do not necessarily play a central role in this regime. A more profound problem is apparently unitarity. These considerations can be illustrated by showing that known gravity and supergravity amplitudes have the same long-distance behavior, despite the extra light states of supergravity, and this serves as an important check on long-range dynamics in a context where perturbative amplitudes are finite. We also argue that these considerations have other important implications: they obstruct probing the conjectured phenomenon of asymptotic safety through a physical scattering process, and gravity appears not to reggeize. These arguments sharpen the need to find a nonpert...

  3. Geometries inherent to N=1 supergravities

    International Nuclear Information System (INIS)

    Galperin, A.S.; Ogievetsky, V.I.; Sokatchev, E.S.

    1981-01-01

    The first part of the talk is devoted to a consideration of linearized N=1 supergravities. The second main part deals with complex geometries inherent to different N=1 supergravities. A special attention is paid to a new version with local symmetry. It is connected to the special nonminimal case (n=0) having a remarkable property of supervolume preservation in Csup(4.4) superspace. Therefore the superdeterminant of change of variables from left to right-handed Rsup(4.4) parametrization is a dimensionless scalar. This geometric invariant has to be constrained to obtain an action. Solving such a constraint on vector and spinor prepotentials in Wess-Zumino gauge one obtains the new supergravity with 12+12 fields and local symmetry. A possible relaxation of this constraint is briefly considered (16+16 fields version) [ru

  4. Euclidean supergravity and multi-centered solutions

    Directory of Open Access Journals (Sweden)

    W.A. Sabra

    2017-04-01

    Full Text Available In ungauged supergravity theories, the no-force condition for BPS states implies the existence of stable static multi-centered solutions. The first solutions to Einstein–Maxwell theory with a positive cosmological constant describing an arbitrary number of charged black holes were found by Kastor and Traschen. Generalisations to five and higher dimensional theories were obtained by London. Multi-centered solutions in gauged supergravity, even with time-dependence allowed, have yet to be constructed. In this letter we construct supersymmetry-preserving multi-centered solutions for the case of D=5, N=2 Euclidean gauged supergravity coupled to an arbitrary number of vector multiplets. Higher dimensional Einstein–Maxwell multi-centered solutions are also presented.

  5. N=2 no-scale supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Itoyama, H.; McLerran, L.; Taylor, T.R.; Van der Bij, J.J.

    1987-01-12

    N=2 extended supergravity is discussed and an assessment is made of the problems encountered in applying it to the construction of phenomenological models of particle physics. A specific class of so-called no-scale models is discussed, in which the two supersymmetries are spontaneously broken in flat space-time, with naturally vanishing cosmological constant and the symmetry breaking undetermined at the classical level. Supergravity-induced supersymmetry breaking generates effective mass terms for spin-1/2 components of the vector gauge multiplets and spin-0 components of the scalar matter multiplets. For finite globally supersymmetric models, this supersymmetry breaking preserves the finiteness. Possible connections of N=2 no-scale supergravity with superstrings and finite range antigravity are mentioned.

  6. N=2 no-scale supergravity

    International Nuclear Information System (INIS)

    Itoyama, H.; McLerran, L.; Taylor, T.R.; Van der Bij, J.J.

    1987-01-01

    N=2 extended supergravity is discussed and an assessment is made of the problems encountered in applying it to the construction of phenomenological models of particle physics. A specific class of so-called no-scale models is discussed, in which the two supersymmetries are spontaneously broken in flat space-time, with naturally vanishing cosmological constant and the symmetry breaking undetermined at the classical level. Supergravity-induced supersymmetry breaking generates effective mass terms for spin-1/2 components of the vector gauge multiplets and spin-0 components of the scalar matter multiplets. For finite globally supersymmetric models, this supersymmetry breaking preserves the finiteness. Possible connections of N=2 no-scale supergravity with superstrings and finite range antigravity are mentioned. (orig.)

  7. The antigravitation phenomenon in supergravity theories

    International Nuclear Information System (INIS)

    Kotrla, M.

    1984-01-01

    The supergravity theories describe the interaction of particles by means of the local field theory, contain the gravitational field and are invariant relative to local supersymmetry. In supergravity models gravitational interaction is mediated not only by the usual tensor field with spin two but also by a vector field and possibly by a scalar field. This results in the fact that in supergravity theories the gravitational force between a particle and an antiparticle may increase over small distances, and the gravitational force between two particles or two antiparticles may disappear. The properties of the model may be summed up by saying that the model is generally covariant but leads to the disturbance of the weak principle of equivalence, the gravitational law differs from Newton's law at small distances, and particles and antiparticles do not have the same mass. (B.S.)

  8. Lagrangians of N=2 supergravity-matter systems

    International Nuclear Information System (INIS)

    Wit, B. de; Proeyen, A. van; Lauwers, P.G.

    1984-12-01

    We present explicit expressions for general actions of vector and scalar multiplets coupled to N=2 supergravity. We outline their construction which is based on the superconformal tensor calculus. The vector multiplets may be associated with a gauge group G which may also act on the scalar multiplets. The latter are naturally described in terms of quaternions; in the simplest case their kinetic terms define a nonlinear sigma model of a quaternionic projective space. We give an extension of the vector multiplet action which is not obtained from a chiral superspace density, and contains a Chern-Simons-type term. Transformation rules are given and the conditions for supersymmetry breaking are defined. (orig.)

  9. Topics in supergravity and string theory

    International Nuclear Information System (INIS)

    Eastaugh, A.G.

    1987-01-01

    The first topic covered in this dissertation concerns the harmonic expansion technique and its application to the dimensional compactification of higher dimensional supergravity. A simple example is given to explain the method and then the method is applied to the problem of obtaining the mass spectrum of the squashed seven-sphere compactification of eleven dimensional supergravity. The second topic concerns the application of Fujikawa's method of anomaly calculation to the calculation of the critical dimension of various string models. The third topic is a study and explicit calculation of the Fock space representation of the vertex in Witten's formulation of the interacting open bosonic string field theory

  10. Off-shell Poincaré supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Freedman, Daniel Z. [SITP and Department of Physics, Stanford University,Stanford, California 94305 (United States); Center for Theoretical Physics and Department of Mathematics,Massachusetts Institute of Technology,Cambridge, Massachusetts 02139 (United States); Roest, Diederik [Van Swinderen Institute for Particle Physics and Gravity, University of Groningen,Nijenborgh 4, 9747 AG Groningen (Netherlands); Proeyen, Antoine Van [KU Leuven, Institute for Theoretical Physics,Celestijnenlaan 200D, B-3001 Leuven (Belgium)

    2017-02-21

    We present the action and transformation rules of Poincaré supergravity coupled to chiral multiplets (z{sup α},χ{sup α},h{sup α}) with off-shell auxiliary fields. Starting from the geometric formulation of the superconformal theory with auxiliary fields, we derive the Poincaré counterpart by gauge-fixing the Weyl and chiral symmetry and S-supersymmetry. We show how this transition is facilitated by retaining explicit target-space covariance. Our results form a convenient starting point to study models with constrained superfields, including general matter-coupled de Sitter supergravity.

  11. D=3 unification of curious supergravities

    Energy Technology Data Exchange (ETDEWEB)

    Duff, M.J. [Theoretical Physics, Blackett Laboratory, Imperial College London,London SW7 2AZ (United Kingdom); Mathematical Institute University of Oxford, Andrew Wiles Building,Woodstock Road, Radcliffe Observatory Quarter, Oxford, OX2 6GG (United Kingdom); Ferrara, S. [Theoretical Physics Department, CERN,CH-1211 Geneva (Switzerland); INFN - Laboratori Nazionali di Frascati,Via Enrico Fermi 40, I-00044 Frascati (Italy); Department of Physics and Astronomy andMani L. Bhaumik Institute for Theoretical Physics, UCLA,Los Angeles CA 90095-1547 (United States); Marrani, A. [Museo Storico della Fisica e Centro Studi e Ricerche “Enrico Fermi”,Via Panisperna 89A, I-00184, Roma (Italy); Dipartimento di Fisica e Astronomia “Galileo Galilei”,Università di Padova and INFN, Sez. di Padova,Via Marzolo 8, I-35131 Padova (Italy); Theoretical Physics Department, CERN,CH-1211 Geneva (Switzerland)

    2017-01-09

    We consider the dimensional reduction to D=3 of four maximal-rank supergravities which preserve minimal supersymmetry in D=11, 7, 5 and 4. Such “curious” theories were investigated some time ago, and the four-dimensional one corresponds to an N=1 supergravity with 7 chiral multiplets spanning the seven-disk manifold. Recently, this latter theory provided cosmological models for α-attractors, which are based on the disk geometry with possible restrictions on the parameter α. A unified picture emerges in D=3, where the Ehlers group of General Relativity merges with the S-, T- and U- dualities of the D=4 parent theories.

  12. Formulation of 11-dimensional supergravity in superspace

    International Nuclear Information System (INIS)

    Cremmer, E.; Ferrara, S.

    1980-01-01

    We formulate on-shell 11-dimensional supergravity in superspace and express its equations of motion in terms of purely geometrical quantities. All torsion and curvature components are solved in terms of a single superfield Wsub(rstu), totally antisymmetric in its (flat vector) indices. The dimensional reduction of this formulation is expected to be related to the superspace formulation of N = 8 extended supergravity and might explain the origin of the hidden (local) SU(8) and (global) E 7 symmetries present in this theory. (orig.)

  13. Goldstino superfields in N=2 supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Kuzenko, Sergei M.; McArthur, Ian N. [School of Physics and Astrophysics M013, The University of Western Australia,35 Stirling Highway, Crawley W.A. 6009 (Australia); Tartaglino-Mazzucchelli, Gabriele [Instituut voor Theoretische Fysica, KU Leuven,Celestijnenlaan 200D, B-3001 Leuven (Belgium)

    2017-05-11

    We present off-shell N=2 supergravity actions, which exhibit spontaneously broken local supersymmetry and allow for de Sitter vacua for certain values of the parameters. They are obtained by coupling the standard N=2 supergravity-matter systems to the Goldstino superfields introduced in arXiv:1105.3001 and arXiv:1607.01277 in the rigid supersymmetric case. These N=2 Goldstino superfields include nilpotent chiral and linear supermultiplets. We also describe a new reducible N=1 Goldstino supermultiplet.

  14. Generation of composite operators in supergravity

    International Nuclear Information System (INIS)

    Abdalla, E.

    1984-07-01

    The author discusses the generation of quantum composite operators in two and higher dimensions. In two dimensions the problem is discussed in detail, and the supergravity fields, trivial at the beginning, acquire the status of independent fields, non trivial features being obtained as consequence. In higher dimensions one is led to non compact symmetry groups when dealing with supergravity. The symmetry SU(p,q) is discussed; quantization presents several problems. In one case, p=q, it is possible to obtain a prescription leading to finite results, with a quantization procedure breaking the symmetry to SU(p) X SU(q). (Auth.)

  15. Aspects of Weyl Supergravity arXiv

    CERN Document Server

    Ferrara, Sergio; Lust, Dieter

    In this paper we study the spectrum of all conformal, ${\\cal N}$-extended supergravities (${\\cal N}=1,2,3,4$) in four space-time dimensions. When these theories are obtained as massless limit of Einstein plus Weyl$^2$supergravity, the appropriate counting of the enhanced gauge symmetries allow us to derive the massless spectrum which consist of a dipole ghost graviton multiplet, a ${\\cal N}$-fold tripole ghost gravitino, the third state belonging to a spin 3/2 multiplet and a residual vector multiplet present for non-maximal ${\\cal N}<4$ theories. These theories are not expected to have a standard gravity holographic dual in five dimensions.

  16. D = 3 Unification of Curious Supergravities

    CERN Document Server

    Duff, M.J.; Marrani, A.

    2017-01-09

    We consider the dimensional reduction to D = 3 of four maximal-rank supergravities which preserve minimal supersymmetry in D = 11, 7, 5 and 4. Such "curious" theories were investigated some time ago, and the four-dimensional one corresponds to an N = 1 supergravity with 7 chiral multiplets spanning the seven-disk manifold. Recently, this latter theory was considered to provide cosmological models for alpha-attractors, which are based on the disk geometry with possible restrictions on the parameter alpha. A unified picture emerges in D = 3, where the Ehlers group of General Relativity merges with the S-, T- and U- dualities of the D = 4 parent theories.

  17. Crystal structure of MboIIA methyltransferase.

    Science.gov (United States)

    Osipiuk, Jerzy; Walsh, Martin A; Joachimiak, Andrzej

    2003-09-15

    DNA methyltransferases (MTases) are sequence-specific enzymes which transfer a methyl group from S-adenosyl-L-methionine (AdoMet) to the amino group of either cytosine or adenine within a recognized DNA sequence. Methylation of a base in a specific DNA sequence protects DNA from nucleolytic cleavage by restriction enzymes recognizing the same DNA sequence. We have determined at 1.74 A resolution the crystal structure of a beta-class DNA MTase MboIIA (M.MboIIA) from the bacterium Moraxella bovis, the smallest DNA MTase determined to date. M.MboIIA methylates the 3' adenine of the pentanucleotide sequence 5'-GAAGA-3'. The protein crystallizes with two molecules in the asymmetric unit which we propose to resemble the dimer when M.MboIIA is not bound to DNA. The overall structure of the enzyme closely resembles that of M.RsrI. However, the cofactor-binding pocket in M.MboIIA forms a closed structure which is in contrast to the open-form structures of other known MTases.

  18. Equations of motion for the new D=10 N=1 supergravity-Yang-Mills theory

    International Nuclear Information System (INIS)

    Vashakidze, Sh.I.

    1988-01-01

    An on-shell superfield formulation of the dual (type IB) ten-dimensional N=1 supergravity coupled to Yang-Mills theory is presented. The coupling is completely specified in superspace by A-tensor supercurrent which, at the same time, takes into account all superstring corrections in the slope parameter expansion. The complete set of equations of motion is derived

  19. Construction of N=8 supergravity theories by dimensional reduction

    International Nuclear Information System (INIS)

    Boucher, W.

    1985-01-01

    In this paper I ask which N=8 supergravity theories in four dimensions can be obtained by dimensional reduction of the N=1 supergravity theory in eleven dimensions. Several years ago Scherk and Schwarz produced a particular class of N = 8 theories by giving a dimensional reduction scheme on the restricted class of coset spaces, G/H, with dim H=0 (and therefore dim G=7). I generalize their considerations by looking at arbitrary (seven-dimensional) coset spaces. Also, instead of giving a particular ansatz which happens to work, I set about the distinctly more difficult task of determining all ansatzes which produce N=8 theories. The basic ingredient of my dimensional reduction scheme is the demand that certain symmetries, including supersymmetry, be truncated consistently. I find the surprising result that the only N=8 theories obtainable within the contexts of my scheme are those theories already written down by Scherk and Schwarz. In particular dim H=0 and dim G=7. Independently of these considerations, I prove that any dimensional reduction scheme which consistently truncates supersymmetry must also be consistent with the equations of motion. I discuss Lorentz-invariant solutions of the theories of Scherk and Schwarz, pointing out that since the ansatz of Scherk and Schwarz consistently truncates supersymmetry, any solution of these theories is also a solution of the N=1 supergravity theory in eleven dimensions and, hence, in particular that there is a Freund-Rubin-type ansatz for these theories. However I demonstrate that for most gauge groups the ansatz must be trivial which implies that for these theories the cosmological constant of any Lorentz-invariant solution must be zero (classically). Finally, I make some comparisons with work by Manton on dimensional reduction. (orig.)

  20. Kaluza-Klein supergravity in ten dimensions

    International Nuclear Information System (INIS)

    Huq, M.; Namazie, M.A.

    1983-11-01

    We construct a massive version of N=2 supergravity in ten dimensions by compactification of the eleven dimensional, N=1 theory. This theory describes the usual N=2 massless super-multiplet, in addition to which there is an infinite tower of massive, charged N=2 supermultiplets. (author)

  1. Gauged supergravities in various spacetime dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Weidner, M.

    2006-12-15

    In this thesis we study the gaugings of extended supergravity theories in various space-time dimensions. These theories describe the low-energy limit of non-trivial string compactifications. For each theory under consideration we work out all possible gaugings that are compatible with supersymmetry. They are parameterized by the so-called embedding tensor which is a group theoretical object that has to satisfy certain representation constraints. This embedding tensor determines all couplings in the gauged theory that are necessary to preserve gauge invariance and supersymmetry. The concept of the embedding tensor and the general structure of the gauged supergravities are explained in detail. The methods are then applied to the half-maximal (N=4) supergravities in d=4 and d=5 and to the maximal supergravities in d=2 and d=7. Examples of particular gaugings are given. Whenever possible, the higher-dimensional origin of these theories is identified and it is shown how the compactification parameters like fluxes and torsion are contained in the embedding tensor. (orig.)

  2. Generating geodesic flows and supergravity solutions

    NARCIS (Netherlands)

    Bergshoeff, E.; Chemissany, W.; Ploegh, A.; Trigiante, M.; Van Riet, T.

    2009-01-01

    We consider the geodesic motion on the symmetric moduli spaces that arise after timelike and spacellike reductions of supergravity theories. The geodesics correspond to timelike respectively spacelike p-brane Solutions when they are lifted over a p-dimensional flat space. In particular, we consider

  3. Extremal black holes in N=2 supergravity

    NARCIS (Netherlands)

    Katmadas, S.

    2011-01-01

    An explanation for the entropy of black holes has been an outstanding problem in recent decades. A special case where this is possible is that of extremal black holes in N=2 supergravity in four and five dimensions. The best developed case is for black holes preserving some supersymmetry (BPS),

  4. Spontaneous symmetry breaking in N = 2 supergravity

    International Nuclear Information System (INIS)

    Zinov'ev, Y.M.

    1987-01-01

    A model describing the interaction of N = 2 supergravity with a vector and a linear multiplet is constructed. The model admits the introduction of spontaneous supersymmetry breaking with two arbitrary scales, one of which can be equal to zero, corresponding to the partial super-Higgs effect (N = 2→N = 1). The cosmological term is automatically equal to zero

  5. Local supertwistors and N=2 conformal supergravity

    International Nuclear Information System (INIS)

    Merkulov, S.A.

    1989-01-01

    N = 2 sypersymmetric extension of the local twistor theory is formulated. A supertwistor superconnection determined by the superconformal structure of the base superspace is introduced on the bundle of N = 2 local supertwistors. It is proved that the Yang - Mills equations for this superconnection coincide exactly with the Bach equations describing the dynamics of N 2 conformal supergravity

  6. No-scale supergravity and cosmology

    International Nuclear Information System (INIS)

    Deruelle, N.

    1988-01-01

    The confrontation of current unified theories with cosmoly may prove to be very fruteful. Indeed the demand that the cosmological models they induce match the standard scenario and be free of manifest pathologies imposes severe constraints on them. We thus show that no-scale supergravity (at least its simplest incarnation) may not provide acceptable models of the early universe [fr

  7. Kaluza-Klein theories and supergravity

    CERN Document Server

    CERN. Geneva. Audiovisual Unit

    1986-01-01

    In all recent attempts at a unified description of all fundamental interactions, the idea of introducing extra dimensions has played an important role. This idea becomes even more attractive when combined with the more recent concepts of supersymmetry and supergravity. These topics as well as more recent developments will be reviewed at an introductory level in these lectures.

  8. Graded-Lie-algebra cohomology and supergravity

    International Nuclear Information System (INIS)

    D'Auria, R.; Fre, P.; Regge, T.

    1980-01-01

    Detailed explanations of the cohomology invoked in the group-manifold approach to supergravity is given. The Chevalley cohomology theory of Lie algebras is extended to graded Lie algebras. The scheme of geometrical theories is enlarged so to include cosmological terms and higher powers of the curvature. (author)

  9. Complex linear Goldstino superfield and supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Kuzenko, Sergei M. [School of Physics M013, The University of Western Australia,35 Stirling Highway, Crawley W.A. 6009 (Australia)

    2015-10-01

    The complex linear Goldstino superfield was proposed in http://arxiv.org/abs/1102.3042 for the cases of global and local four-dimensional N=1 supersymmetry. Here we make use of this superfield to construct a supergravity action which is invariant under spontaneously broken local N=1 supersymmetry and has a positive cosmological constant for certain values of the parameters.

  10. Crystal structure of MboIIA methyltransferase

    OpenAIRE

    Osipiuk, Jerzy; Walsh, Martin A.; Joachimiak, Andrzej

    2003-01-01

    DNA methyltransferases (MTases) are sequence-specific enzymes which transfer a methyl group from S-adenosyl-l-methionine (AdoMet) to the amino group of either cytosine or adenine within a recognized DNA sequence. Methylation of a base in a specific DNA sequence protects DNA from nucleolytic cleavage by restriction enzymes recognizing the same DNA sequence. We have determined at 1.74 Å resolution the crystal structure of a β-class DNA MTase MboIIA (M·MboIIA) from the bacterium Moraxella bovis,...

  11. Supergravity and supersymmetry breaking in four and five dimensions

    International Nuclear Information System (INIS)

    Ellis, John; Lalak, Zygmunt; Pokorski, Stefan; Thomas, Steven

    1999-01-01

    We discuss supersymmetry breaking in the field-theoretical limit of the strongly coupled heterotic string compactified on a Calabi-Yau manifold, from the different perspectives of four and five dimensions. The former applies to light degrees of freedom below the threshold for five-dimensional Kaluza-Klein excitations, whereas the five-dimensional perspective is also valid up to the Calabi-Yau scale. We show how, in the latter case, two gauge sectors separated in the fifth dimension are combined to form a consistent four-dimensional supergravity. In the lowest order of the κ 2/3 expansion, we show how a four-dimensional supergravity with gauge kinetic function f 1,2 =S is reproduced, and we show how higher-order terms give rise to four-dimensional operators that differ in the two gauge sectors. In the four-dimensional approach, supersymmetry is seen to be broken when condensates form on one or both walls, and the goldstino may have a non-zero dilatino component. As in the five-dimensional approach, the Lagrangian is not a perfect square, and we have not identified a vacuum with broken supersymmetry and zero vacuum energy. We derive soft supersymmetry-breaking terms for non-standard perturbative embeddings, that are relevant in more general situations such as type I/type IIB orientifold models

  12. Phenomenology of R-parity violating minimal supergravity

    International Nuclear Information System (INIS)

    Bernhardt, M.A.

    2008-02-01

    We investigate in detail the low-energy spectrum of the P 6 violating minimal supergravity model using the SOFTSUSY spectrum code. We impose the experimental constraints from the measurement of the anomalous magnetic moment of the muon (g-2) μ , the b→sγ decay, the branching ration of B s →μ + μ - , as well as the mass bound from direct searches at colliders, in particular the Higgs boson and the lightest Chargino. We focus on regions, where the lightest neutralino is not the lightest supersymmetric particle (LSP). In these regions of parameter space either the lightest scalar tau or one of the sneutrinos is the LSP. We suggest four benchmark points with typical spectra and novel collider signatures which we investigate with a parton level Monte-Carlo simulation. We give an outlook for their detailed phenomenological analysis and simulation by the LHC collaborations, then including detector effects. In addition, we discuss a full Monte-Carlo simulation for single slepton production in association with a single top quark via an LQD type operator at the hadron colliders LHC and Tevatron. We present these results and show a predicted range of detectability for this process- for small couplings in various minimal supergravity models at the LHC. (orig.)

  13. Phenomenology of R-parity violating minimal supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Bernhardt, M.A.

    2008-02-15

    We investigate in detail the low-energy spectrum of the P{sub 6} violating minimal supergravity model using the SOFTSUSY spectrum code. We impose the experimental constraints from the measurement of the anomalous magnetic moment of the muon (g-2){sub {mu}}, the b{yields}s{gamma} decay, the branching ration of B{sub s}{yields}{mu}{sup +}{mu}{sup -}, as well as the mass bound from direct searches at colliders, in particular the Higgs boson and the lightest Chargino. We focus on regions, where the lightest neutralino is not the lightest supersymmetric particle (LSP). In these regions of parameter space either the lightest scalar tau or one of the sneutrinos is the LSP. We suggest four benchmark points with typical spectra and novel collider signatures which we investigate with a parton level Monte-Carlo simulation. We give an outlook for their detailed phenomenological analysis and simulation by the LHC collaborations, then including detector effects. In addition, we discuss a full Monte-Carlo simulation for single slepton production in association with a single top quark via an LQD type operator at the hadron colliders LHC and Tevatron. We present these results and show a predicted range of detectability for this process- for small couplings in various minimal supergravity models at the LHC. (orig.)

  14. Minimal set of auxiliary fields and S-matrix for extended supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Fradkin, E S; Vasiliev, M A [Physical Lebedev Institute - Moscow

    1979-05-19

    Minimal set of auxiliary fields for linearized SO(2) supergravity and one-parameter extension of the minimal auxiliary fields in the SO(1) supergravity are constructed. The expression for the S-matrix in SO(2) supergravity are given.

  15. 3D gauged supergravity from SU(2) reduction of $N=1$ 6D supergravity

    CERN Document Server

    Gava, Edi; Narain, K S

    2010-01-01

    We obtain Yang-Mills $SU(2)\\times G$ gauged supergravity in three dimensions from $SU(2)$ group manifold reduction of (1,0) six dimensional supergravity coupled to an anti-symmetric tensor multiplet and gauge vector multiplets in the adjoint of $G$. The reduced theory is consistently truncated to $N=4$ 3D supergravity coupled to $4(1+\\textrm{dim}\\, G)$ bosonic and $4(1+\\textrm{dim}\\, G)$ fermionic propagating degrees of freedom. This is in contrast to the reduction in which there are also massive vector fields. The scalar manifold is $\\mathbf{R}\\times \\frac{SO(3,\\, \\textrm{dim}\\, G)}{SO(3)\\times SO(\\textrm{dim}\\, G)}$, and there is a $SU(2)\\times G$ gauge group. We then construct $N=4$ Chern-Simons $(SO(3)\\ltimes \\mathbf{R}^3)\\times (G\\ltimes \\mathbf{R}^{\\textrm{dim}G})$ three dimensional gauged supergravity with scalar manifold $\\frac{SO(4,\\,1+\\textrm{dim}G)}{SO(4)\\times SO(1+\\textrm{dim}G)}$ and explicitly show that this theory is on-shell equivalent to the Yang-Mills $SO(3)\\times G$ gauged supergravity the...

  16. Generalized supersymmetric cosmological term in N=1 supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Concha, P.K.; Rodríguez, E.K. [Departamento de Física, Universidad de Concepción,Casilla 160-C, Concepción (Chile); Dipartimento di Scienza Applicata e Tecnologia (DISAT), Politecnico di Torino,Corso Duca degli Abruzzi 24, I-10129 Torino (Italy); Istituto Nazionale di Fisica Nucleare (INFN) Sezione di Torino,Via Pietro Giuria 1, 10125 Torino (Italy); Salgado, P. [Departamento de Física, Universidad de Concepción,Casilla 160-C, Concepción (Chile)

    2015-08-04

    An alternative way of introducing the supersymmetric cosmological term in a supergravity theory is presented. We show that the AdS-Lorentz superalgebra allows to construct a geometrical formulation of supergravity containing a generalized supersymmetric cosmological constant. The N=1, D=4 supergravity action is built only from the curvatures of the AdS-Lorentz superalgebra and corresponds to a MacDowell-Mansouri like action. The extension to a generalized AdS-Lorentz superalgebra is also analyzed.

  17. Generalized Attractor Points in Gauged Supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Kachru, Shamit; /Stanford U., Phys. Dept. /SLAC; Kallosh, Renata; /Stanford U., Phys. Dept.; Shmakova, Marina; /KIPAC, Menlo Park /SLAC /Stanford U., Phys. Dept.

    2011-08-15

    The attractor mechanism governs the near-horizon geometry of extremal black holes in ungauged 4D N=2 supergravity theories and in Calabi-Yau compactifications of string theory. In this paper, we study a natural generalization of this mechanism to solutions of arbitrary 4D N=2 gauged supergravities. We define generalized attractor points as solutions of an ansatz which reduces the Einstein, gauge field, and scalar equations of motion to algebraic equations. The simplest generalized attractor geometries are characterized by non-vanishing constant anholonomy coefficients in an orthonormal frame. Basic examples include Lifshitz and Schroedinger solutions, as well as AdS and dS vacua. There is a generalized attractor potential whose critical points are the attractor points, and its extremization explains the algebraic nature of the equations governing both supersymmetric and non-supersymmetric attractors.

  18. High energy scattering in gravity and supergravity

    DEFF Research Database (Denmark)

    B. Giddings, Steven; Schmidt-Sommerfeld, Maximilian; Andersen, Jeppe Rosenkrantz

    2010-01-01

    We investigate features of perturbative gravity and supergravity by studying scattering in the ultraplanckian limit, and sharpen arguments that the dynamics is governed by long-distance physics. A simple example capturing aspects of the eikonal resummation suggests why short distance phenomena...... and in particular divergences or nonrenormalizability do not necessarily play a central role in this regime. A more profound problem is apparently unitarity. These considerations can be illustrated by showing that known gravity and supergravity amplitudes have the same long-distance behavior, despite the extra...... a physical scattering process, and ultraplanckian scattering exhibiting Regge behavior. These arguments sharpen the need to find a nonperturbative completion of gravity with mechanisms which restore unitarity in the strong gravity regime....

  19. HKT geometry and de Sitter supergravity

    International Nuclear Information System (INIS)

    Grover, Jai; Gutowski, Jan B.; Herdeiro, Carlos A.R.; Sabra, Wafic

    2009-01-01

    Solutions of five-dimensional minimal de Sitter supergravity admitting Killing spinors are considered. It is shown that the 'timelike' solutions are determined in terms of a four-dimensional hyper-Kaehler torsion (HKT) manifold. If the HKT manifold is conformally hyper-Kaehler the most general solution can be obtained from a sub-class of supersymmetric solutions of minimal N=2 ungauged supergravity, by means of a simple transformation. Examples include a multi-BMPV de Sitter solution, describing multiple rotating black holes co-moving with the expansion of the universe. If the HKT manifold is not conformally hyper-Kaehler, examples admitting a tri-holomorphic Killing vector field are constructed in terms of certain solutions of three-dimensional Einstein-Weyl geometry

  20. Pole inflation in Jordan frame supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Saikawa, Ken' ichi [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Yamaguchi, Masahide [Tokyo Institute of Technology, Ookayama (Japan). Dept. of Physics; Yamashita, Yasuho [Kyoto Univ. (Japan). Yukawa Inst. for Theoretical Physics; Yoshida, Daisuke [Montreal Univ., QC (Canada). Dept. of Physics

    2017-09-15

    We investigate inflation models in Jordan frame supergravity, in which an inflaton non-minimally couples to the scalar curvature. By imposing the condition that an inflaton would have the canonical kinetic term in the Jordan frame, we construct inflation models with asymptotically flat potential through pole inflation technique and discuss their relation to the models based on Einstein frame supergravity. We also show that the model proposed by Ferrara et al. has special position and the relation between the Kaehler potential and the frame function is uniquely determined by requiring that scalars take the canonical kinetic terms in the Jordan frame and that a frame function consists only of a holomorphic term (and its anti-holomorphic counterpart) for symmetry breaking terms. Our case corresponds to relaxing the latter condition.

  1. Stable supergravity dual of nonsupersymmetric glue

    International Nuclear Information System (INIS)

    Babington, James; Crooks, David E.; Evans, Nick

    2003-01-01

    We study nonsupersymmetric fermion mass and condensate deformations of the AdS conformal field theory correspondence. The five dimensional supergravity flows are lifted to a complete and remarkably simple ten dimensional background. A brane probe analysis shows that when all the fermions have an equal mass a positive mass is generated for all six scalar fields leaving nonsupersymmetric Yang-Mills theory in the deep infrared. We numerically determine the potential, produced by the background, in the Schroedinger equation relevant to the study of O ++ glueballs. The potential is a bounded well, providing evidence of stability and for a discrete, confined spectrum. The geometry can also describe the supergravity background around an (unstable) fuzzy 5-brane

  2. Pole inflation in Jordan frame supergravity

    International Nuclear Information System (INIS)

    Saikawa, Ken'ichi; Yamaguchi, Masahide; Yamashita, Yasuho; Yoshida, Daisuke

    2017-09-01

    We investigate inflation models in Jordan frame supergravity, in which an inflaton non-minimally couples to the scalar curvature. By imposing the condition that an inflaton would have the canonical kinetic term in the Jordan frame, we construct inflation models with asymptotically flat potential through pole inflation technique and discuss their relation to the models based on Einstein frame supergravity. We also show that the model proposed by Ferrara et al. has special position and the relation between the Kaehler potential and the frame function is uniquely determined by requiring that scalars take the canonical kinetic terms in the Jordan frame and that a frame function consists only of a holomorphic term (and its anti-holomorphic counterpart) for symmetry breaking terms. Our case corresponds to relaxing the latter condition.

  3. Tensor calculus for supergravity on a manifold with boundary

    International Nuclear Information System (INIS)

    Belyaev, Dmitry V.; Nieuwenhuizen, Peter van

    2008-01-01

    Using the simple setting of 3D N = 1 supergravity, we show how the tensor calculus of supergravity can be extended to manifolds with boundary. We present an extension of the standard F-density formula which yields supersymmetric bulk-plus-boundary actions. To construct additional separately supersymmetric boundary actions, we decompose bulk supergravity and bulk matter multiplets into co-dimension one submultiplets. As an illustration we obtain the supersymmetric extension of the York-Gibbons-Hawking extrinsic curvature boundary term. We emphasize that our construction does not require any boundary conditions on off-shell fields. This gives a significant improvement over the existing orbifold supergravity tensor calculus

  4. One-loop infinities in dimensionally reduced supergravities

    International Nuclear Information System (INIS)

    Fradkin, E.S.; Tseytlin, A.A.

    1983-11-01

    It is proved explicitly in the paper that d=4 theory following via reduction from N=1, d=10 supergravities is not finite at one loop while the version of N=8 supergravity directly following from N=1, d=11 theory is one-loop finite. The method used is based on quantization of initial higher dimensional theory as a first step. The results also suggest possible existence of non-standard (higher N) d>4 supergravities which reduce to d=4 theories with finite N=8 supergravity sector. (author)

  5. Tanshinone IIA protects PC12 cells from β-amyloid(25-35)-induced apoptosis via PI3K/Akt signaling pathway.

    Science.gov (United States)

    Dong, Huimin; Mao, Shanping; Mao, Shanpin; Wei, Jiajun; Liu, Baohui; Zhang, Zhaohui; Zhang, Qian; Yan, Mingmin

    2012-06-01

    For the aging populations of any nation, Dementia is becoming a primary problem and Alzheimer’s dementia (AD) is the most common type. However, until now, there is no effective treatment for AD. Tanshinone IIA (Tan IIA) has been reported for neuroprotective potential to against amyloid β peptides (Aβ)-induced cytotoxicity in the rat pheochromocytoma cell line PC-12, which is widely used as AD research model, but the mechanism still remains unclear. To investigate the effect of Tan IIA and the possible molecular mechanism in the apoptosis of PC12 cells, we induced apoptosis in PC12 cells with β-amyloid(25-35), and treated cells with Tan IIA. After 24 h treatment, we found that Tan IIA increased the cell viability and reduced the number of apoptotic cells induced by Aβ(25-35). However, neuroprotection of Tan IIA was abolished by PI3K inhibitor LY294002. Meanwhile, Treatment with lithium chloride, a phosphorylation inhibitor of GSK3β, which is a downstream target of PI3K/Akt, can block Aβ(25-35)-induced cell apoptosis in a Tan IIA-like manner. Our findings suggest that Tan IIA is an effective neuroprotective agent and a viable candidate in AD therapy and PI3K/Akt activation and GSK3β phosphorylation are involved in the neuroprotection of Tan IIA.

  6. Gravitino problem in minimal supergravity inflation

    Directory of Open Access Journals (Sweden)

    Fuminori Hasegawa

    2017-04-01

    Full Text Available We study non-thermal gravitino production in the minimal supergravity inflation. In this minimal model utilizing orthogonal nilpotent superfields, the particle spectrum includes only graviton, gravitino, inflaton, and goldstino. We find that a substantial fraction of the cosmic energy density can be transferred to the longitudinal gravitino due to non-trivial change of its sound speed. This implies either a breakdown of the effective theory after inflation or a serious gravitino problem.

  7. Gravitino problem in minimal supergravity inflation

    Energy Technology Data Exchange (ETDEWEB)

    Hasegawa, Fuminori [Institute for Cosmic Ray Research, The University of Tokyo, Kashiwa, Chiba 277-8582 (Japan); Mukaida, Kyohei [Kavli IPMU (WPI), UTIAS, The University of Tokyo, Kashiwa, Chiba 277-8583 (Japan); Nakayama, Kazunori [Department of Physics, Faculty of Science, The University of Tokyo, Bunkyo-ku, Tokyo 133-0033 (Japan); Terada, Takahiro, E-mail: terada@kias.re.kr [School of Physics, Korea Institute for Advanced Study (KIAS), Seoul 02455 (Korea, Republic of); Yamada, Yusuke [Stanford Institute for Theoretical Physics and Department of Physics, Stanford University, Stanford, CA 94305 (United States)

    2017-04-10

    We study non-thermal gravitino production in the minimal supergravity inflation. In this minimal model utilizing orthogonal nilpotent superfields, the particle spectrum includes only graviton, gravitino, inflaton, and goldstino. We find that a substantial fraction of the cosmic energy density can be transferred to the longitudinal gravitino due to non-trivial change of its sound speed. This implies either a breakdown of the effective theory after inflation or a serious gravitino problem.

  8. On the construction of supergravity theories

    International Nuclear Information System (INIS)

    Holten, J.W. van.

    1980-01-01

    A precise and technical definition of supersymmetry is given. The theory of SO(2) supergravity is presented. The linearized version of the full multiplet, including auxiliary fields, of this theory as well as of certain matter multiplets, are constructed. These results are extended to all orders in the coupling constant kappa. Finally, the quantization procedure for theories with local gauge invariance and its generalization for theories with non-closing, or open, gauge algebras is presented. (Auth.)

  9. Ultraviolet Behavior of N = 8 Supergravity

    International Nuclear Information System (INIS)

    Dixon, Lance J.

    2010-01-01

    In these lectures the author describes the remarkable ultraviolet behavior of N = 8 supergravity, which through four loops is no worse than that of N = 4 super-Yang-Mills theory (a finite theory). I also explain the computational tools that allow multi-loop amplitudes to be evaluated in this theory - the KLT relations and the unitarity method - and sketch how ultraviolet divergences are extracted from the amplitudes.

  10. Newton-Cartan supergravity with torsion and Schrödinger supergravity

    International Nuclear Information System (INIS)

    Bergshoeff, Eric; Rosseel, Jan; Zojer, Thomas

    2015-01-01

    We derive a torsionfull version of three-dimensional N=2 Newton-Cartan supergravity using a non-relativistic notion of the superconformal tensor calculus. The “superconformal” theory that we start with is Schrödinger supergravity which we obtain by gauging the Schrödinger superalgebra. We present two non-relativistic N=2 matter multiplets that can be used as compensators in the superconformal calculus. They lead to two different off-shell formulations which, in analogy with the relativistic case, we call “old minimal” and “new minimal” Newton-Cartan supergravity. We find similarities but also point out some differences with respect to the relativistic case.

  11. Newton-Cartan supergravity with torsion and Schrödinger supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Bergshoeff, Eric [Van Swinderen Institute for Particle Physics and Gravity, University of Groningen,Nijenborgh 4, 9747 AG Groningen (Netherlands); Rosseel, Jan [Institute for Theoretical Physics, Vienna University of Technology,Wiedner Hauptstr. 8-10/136, A-1040 Vienna (Austria); Albert Einstein Center for Fundamental Physics, University of Bern,Sidlerstrasse 5, 3012 Bern (Switzerland); Zojer, Thomas [Van Swinderen Institute for Particle Physics and Gravity, University of Groningen,Nijenborgh 4, 9747 AG Groningen (Netherlands)

    2015-11-25

    We derive a torsionfull version of three-dimensional N=2 Newton-Cartan supergravity using a non-relativistic notion of the superconformal tensor calculus. The “superconformal” theory that we start with is Schrödinger supergravity which we obtain by gauging the Schrödinger superalgebra. We present two non-relativistic N=2 matter multiplets that can be used as compensators in the superconformal calculus. They lead to two different off-shell formulations which, in analogy with the relativistic case, we call “old minimal” and “new minimal” Newton-Cartan supergravity. We find similarities but also point out some differences with respect to the relativistic case.

  12. Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis.

    Science.gov (United States)

    Mihaylova, Maria M; Vasquez, Debbie S; Ravnskjaer, Kim; Denechaud, Pierre-Damien; Yu, Ruth T; Alvarez, Jacqueline G; Downes, Michael; Evans, Ronald M; Montminy, Marc; Shaw, Reuben J

    2011-05-13

    Class IIa histone deacetylases (HDACs) are signal-dependent modulators of transcription with established roles in muscle differentiation and neuronal survival. We show here that in liver, class IIa HDACs (HDAC4, 5, and 7) are phosphorylated and excluded from the nucleus by AMPK family kinases. In response to the fasting hormone glucagon, class IIa HDACs are rapidly dephosphorylated and translocated to the nucleus where they associate with the promoters of gluconeogenic enzymes such as G6Pase. In turn, HDAC4/5 recruit HDAC3, which results in the acute transcriptional induction of these genes via deacetylation and activation of FOXO family transcription factors. Loss of class IIa HDACs in murine liver results in inhibition of FOXO target genes and lowers blood glucose, resulting in increased glycogen storage. Finally, suppression of class IIa HDACs in mouse models of type 2 diabetes ameliorates hyperglycemia, suggesting that inhibitors of class I/II HDACs may be potential therapeutics for metabolic syndrome. Copyright © 2011 Elsevier Inc. All rights reserved.

  13. Alkali metals and group IIA metals

    International Nuclear Information System (INIS)

    Fenton, D.E.

    1987-01-01

    This chapter on the coordination complexes of the alkali metals of group IIA starts with a historical perspective of their chemistry, from simple monodentate ligands, metal-β-diketonates to the macrocyclic polyethers which act as ligands to the alkali and akaline earth metals. Other macrocyclic ligands include quarterenes, calixarenes, porphyrins, phthalocyanines and chlorophylls. A section on the naturally occurring ionophores and carboxylic ionophores is included. (UK)

  14. Higher derivative couplings and massive supergravity in three dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Kuzenko, Sergei M.; Novak, Joseph [School of Physics M013, The University of Western Australia,35 Stirling Highway, Crawley W.A. 6009 (Australia); Tartaglino-Mazzucchelli, Gabriele [School of Physics M013, The University of Western Australia,35 Stirling Highway, Crawley W.A. 6009 (Australia); Instituut voor Theoretische Fysica, KU Leuven,Celestijnenlaan 200D, B-3001 Leuven (Belgium)

    2015-09-14

    We develop geometric superspace settings to construct arbitrary higher derivative couplings (including R{sup n} terms) in three-dimensional supergravity theories with N≤3 by realising them as conformal supergravity coupled to certain compensators. For all known off-shell supergravity formulations, we construct supersymmetric invariants with up to and including four derivatives. As a warming-up exercise, we first give a new and completely geometric derivation of such invariants in N=1 supergravity. Upon reduction to components, they agree with those given in http://arxiv.org/abs/0907.4658 and http://arxiv.org/abs/1005.3952. We then carry out a similar construction in the case of N=2 supergravity for which there exist two minimal formulations that differ by the choice of compensating multiplet: (i) a chiral scalar multipet; (ii) a vector multiplet. For these formulations all four derivative invariants are constructed in completely general and gauge independent form. For a general supergravity model (in the N=1 and minimal N=2 cases) with curvature-squared and lower order terms, we derive the superfield equations of motion, linearise them about maximally supersymmetric backgrounds and obtain restrictions on the parameters that lead to models for massive supergravity. We use the non-minimal formulation for N=2 supergravity (which corresponds to a complex linear compensator) to construct a novel consistent theory of massive supergravity. In the case of N=3 supergravity, we employ the off-shell formulation with a vector multiplet as compensator to construct for the first time various higher derivative invariants. These invariants may be used to derive models for N=3 massive supergravity. As a bi-product of our analysis, we also present superfield equations for massive higher spin multiplets in (1,0), (1,1) and (2,0) anti-de Sitter superspaces.

  15. The general supersymmetric solution of topologically massive supergravity

    International Nuclear Information System (INIS)

    Gibbons, G W; Pope, C N; Sezgin, E

    2008-01-01

    We find the general fully nonlinear solution of topologically massive supergravity admitting a Killing spinor. It is of plane-wave type, with a null Killing vector field. Conversely, we show that all solutions with a null Killing vector are supersymmetric for one or the other choice of sign for the Chern-Simons coupling constant μ. If μ does not take the critical value, μ = ±1, these solutions are asymptotically regular on a Poincare patch, but do not admit a smooth global compactification with boundary S 1 x R. In the critical case, the solutions have a logarithmic singularity on the boundary of the Poincare patch. We derive a Nester-Witten identity, which allows us to identify the associated charges, but we conclude that the presence of the Chern-Simons term prevents us from making a statement about their positivity. The Nester-Witten procedure is applied to the BTZ black hole

  16. On the stability of non-supersymmetric supergravity solutions

    Science.gov (United States)

    Imaanpur, Ali; Zameni, Razieh

    2017-09-01

    We examine the stability of some non-supersymmetric supergravity solutions that have been found recently. The first solution is AdS5 ×M6, for M6 an stretched CP3. We consider breathing and squashing mode deformations of the metric, and find that the solution is stable against small fluctuations of this kind. Next we consider type IIB solution of AdS2 ×M8, where the compact space is a U (1) bundle over N (1 , 1). We study its stability under the deformation of M8 and the 5-form flux. In this case we also find that the solution is stable under small fluctuation modes of the corresponding deformations.

  17. On the stability of non-supersymmetric supergravity solutions

    Directory of Open Access Journals (Sweden)

    Ali Imaanpur

    2017-09-01

    Full Text Available We examine the stability of some non-supersymmetric supergravity solutions that have been found recently. The first solution is AdS5×M6, for M6 an stretched CP3. We consider breathing and squashing mode deformations of the metric, and find that the solution is stable against small fluctuations of this kind. Next we consider type IIB solution of AdS2×M8, where the compact space is a U(1 bundle over N(1,1. We study its stability under the deformation of M8 and the 5-form flux. In this case we also find that the solution is stable under small fluctuation modes of the corresponding deformations.

  18. N=1 supergravity off-shell in six dimensions

    International Nuclear Information System (INIS)

    Smith, A.W.

    1983-01-01

    It is shown that the N=1 supergravity in six dimensions showns useful characteristics to study the unification of a gauge theory together with the supergravity, via dimensinal reduction, giving a geometrical interpretation for the internal quantum numbers in the reduced theory. (L.C.) [pt

  19. Construction of the superalgebras for N=1 supergravity

    International Nuclear Information System (INIS)

    Ivanov, E.A.; Niederle, J.

    1984-11-01

    It is shown that the infinite parameter gauge superalgebras of the conformal and of the N=1 Einstein supergravities can be obtained as the closures of various two finite-parameter superalgebras. In the conformal case the standard, minimal and Einsteinian closures are studied. In the case of the N=1 Einstein supergravities the minimal and non-minimal closures are discussed. (author)

  20. The Bianchi classification of maximal D = 8 gauged supergravities

    NARCIS (Netherlands)

    Bergshoeff, Eric; Gran, Ulf; Linares, Román; Nielsen, Mikkel; Ortín, Tomás; Roest, Diederik

    2003-01-01

    We perform the generalized dimensional reduction of D = 11 supergravity over three-dimensional group manifolds as classified by Bianchi. Thus, we construct 11 different maximal D = 8 gauged supergravities, two of which have an additional parameter. One class of group manifolds (class B) leads to

  1. The Bianchi classification of maximal D=8 gauged supergravities

    NARCIS (Netherlands)

    Bergshoeff, E; Gran, U; Linares, R; Nielsen, M; Ortin, T; Roest, D

    2003-01-01

    We perform the generalized dimensional reduction of D = 11 supergravity over three-dimensional group manifolds as classified by Bianchi. Thus, we construct 11 different maximal D = 8 gauged supergravities, two of which have an additional parameter. One class of group manifolds (class B) leads to

  2. A dangerous liaison: Leptin and sPLA2-IIA join forces to induce proliferation and migration of astrocytoma cells.

    Directory of Open Access Journals (Sweden)

    Rubén Martín

    Full Text Available Glioblastoma, the most aggressive type of primary brain tumour, shows worse prognosis linked to diabetes or obesity persistence. These pathologies are chronic inflammatory conditions characterized by altered profiles of inflammatory mediators, including leptin and secreted phospholipase A2-IIA (sPLA2-IIA. Both proteins, in turn, display diverse pro-cancer properties in different cell types, including astrocytes. Herein, to understand the underlying relationship between obesity and brain tumors, we investigated the effect of leptin, alone or in combination with sPLA2-IIA on astrocytoma cell functions. sPLA2-IIA induced up-regulation of leptin receptors in 1321N1 human astrocytoma cells. Leptin, as well as sPLA2-IIA, increased growth and migration in these cells, through activation/phosphorylation of key proteins of survival cascades. Leptin, at concentrations with minimal or no activating effects on astrocytoma cells, enhanced growth and migration promoted by low doses of sPLA2-IIA. sPLA2-IIA alone induced a transient phosphorylation pattern in the Src/ERK/Akt/mTOR/p70S6K/rS6 pathway through EGFR transactivation, and co-addition of leptin resulted in a sustained phosphorylation of these signaling regulators. Mechanistically, EGFR transactivation and tyrosine- and serine/threonine-protein phosphatases revealed a key role in this leptin-sPLA2-IIA cross-talk. This cooperative partnership between both proteins was also found in primary astrocytes. These findings thus indicate that the adipokine leptin, by increasing the susceptibility of cells to inflammatory mediators, could contribute to worsen the prognosis of tumoral and neurodegenerative processes, being a potential mediator of some obesity-related medical complications.

  3. The no-hair conjecture in 2D dilaton supergravity

    International Nuclear Information System (INIS)

    Gamboa, J.; Georgelin, Y.

    1993-06-01

    Two dimensional dilaton gravity and supergravity are studied following Hamiltonian methods. The structure of constraints of 2D dilaton gravity and the 2D dilaton supergravity theory is discussed taking the square root of the bosonic constraints. The equations of motion are integrated in both cases, and it is shown that the solutions of the equation of motion of 2D dilaton supergravity differs from the solutions of 2D dilaton gravity only by boundary conditions on the fermionic variables, i.e. the black holes of 2D dilaton supergravity theory are exactly the same black holes of 2D bosonic dilaton gravity modulo supersymmetry transformations. This result is the bidimensional analogue of the no-hair theorem for supergravity. (authors). 28 refs

  4. Physics of superheavy dark matter in supergravity

    Science.gov (United States)

    Addazi, Andrea; Marciano, Antonino; Ketov, Sergei V.; Khlopov, Maxim Yu.

    New trends in inflationary model building and dark matter production in supergravity are considered. Starobinsky inflation is embedded into 𝒩 = 1 supergravity, avoiding instability problems, when the inflaton belongs to a vector superfield associated with a U(1) gauge symmetry, instead of a chiral superfield. This gauge symmetry can be spontaneously broken by the super-Higgs mechanism resulting in a massive vector supermultiplet including the (real scalar) inflaton field. Both supersymmetry (SUSY) and the R-symmetry can also be spontaneously broken by the Polonyi mechanism at high scales close to the inflationary scale. In this case, Polonyi particles and gravitinos become superheavy, and can be copiously produced during inflation by the Schwinger mechanism sourced by the universe expansion. The Polonyi mass slightly exceeds twice the gravitino mass, so that Polonyi particles are unstable and decay into gravitinos. Considering the mechanisms of superheavy gravitino production, we find that the right amount of cold dark matter composed of gravitinos can be achieved. In our scenario, the parameter space of the inflaton potential is directly related to the dark matter one, providing a new unifying framework of inflation and dark matter genesis. A multi-superfield extension of the supergravity framework with a single (inflaton) superfield can result in a formation of primordial nonlinear structures like mini- and stellar-mass black holes, primordial nongaussianity, and the running spectral index of density fluctuations. This framework can be embedded into the SUSY GUTs inspired by heterotic string compactifications on Calabi-Yau three-folds, thus unifying particle physics with quantum gravity.

  5. Inflaton decay in supergravity and gravitino problem

    International Nuclear Information System (INIS)

    Takahashi, F.

    2007-09-01

    We have recently shown that, if the inflaton has a nonzero vacuum expectation value, it generically couples to any matter fields that appear in the superpotential at the tree level, and to any gauge sectors through anomalies in the supergravity. Through these processes, the inflaton decays into the supersymmetry breaking sector, producing many gravitinos. The inflaton also directly decays into a pair of the gravitinos. Taking account of these processes, we derive constraints on both inflation models and supersymmetry breaking scenarios for avoiding overproduction of the gravitinos. (orig.)

  6. Gauged N=8 d=5 supergravity

    International Nuclear Information System (INIS)

    Pernici, M.; Pilch, K.; Van Nieuwenhuizen, P.

    1985-01-01

    The complete gauged nonlinear N=8 d=5 supergravity action and supersymmetry transformation laws (without four- and three-fermion terms) are presented. They are obtained from the ungauged model by reinterpreting part of the field strengths of the abelian vector fields as real self-dual second-rank antisymmetric tensors. The complete set of T-tensor indentities are given and their validity is checked numerically. The model has a local Yang-Mills SO(6) and a local composite USp(8) symmetry. The self-duality is essential for the consistent coupling of the antisymmetric tensors to the nonabelian gauge fields. (orig.)

  7. The axion mass in modular invariant supergravity

    International Nuclear Information System (INIS)

    Butter, Daniel; Gaillard, Mary K.

    2005-01-01

    When supersymmetry is broken by condensates with a single condensing gauge group, there is a nonanomalous R-symmetry that prevents the universal axion from acquiring a mass. It has been argued that, in the context of supergravity, higher dimension operators will break this symmetry and may generate an axion mass too large to allow the identification of the universal axion with the QCD axion. We show that such contributions to the axion mass are highly suppressed in a class of models where the effective Lagrangian for gaugino and matter condensation respects modular invariance (T-duality)

  8. Residual supersymmetry of compactified d = 10 supergravity

    International Nuclear Information System (INIS)

    Wit, B. de; Smit, D.J.; Hari Dass, N.D.

    1986-05-01

    The conditions for residual supersymmetry in compactified ten-dimensional supergravity theories are investigated, including the effect of a non-constant 'warp factor'. The analysis is based on on-shell transformation laws which implies that certain linear combinations of classical field equations must be satisfied. The conditions for superysymmetry are, in general, not very restrictive. When, in addition, one assumes the validity of Bianchi identities, two independent contractions of the Einstein equation are implied. These equations exclude d=4 de Sitter space; for compactifications to d=4 Minkowski space they only allow purely metric Ricci-flat field configurations with constant warp factor. (Auth.)

  9. The simplest group of Einstein supergravity

    International Nuclear Information System (INIS)

    Ogievetsky, V.I.; Sokatchev, E.S.

    1979-01-01

    The simplest supergroup of Einstein supergravity is considered. It is the complex supergroup of general coordinate transformations in left- and right-handed chiral conjugated superspaces restricted by the condition of left- and right- supervolume-preservation. The real part of the vector coordinate of the superspace is identified with the space-time coordinate xsup(m) and the imaginary one, with the axial gravitational superfield Hsup(m) (x, theta, anti theta). The transformations of the field components of Hsup(m) are studied in detail. The approach described is the geometrical basis of the so-called ''tensor calculus''

  10. Symmetry enhancement of extremal horizons in D  =  5 supergravity

    Science.gov (United States)

    Kayani, U.

    2018-06-01

    We consider the near-horizon geometry of supersymmetric extremal black holes in un-gauged and gauged 5-dimensional supergravity, coupled to abelian vector multiplets. By analyzing the global properties of the Killing spinors, we prove that the near-horizon geometries undergo a supersymmetry enhancement. This follows from a set of generalized Lichnerowicz-type theorems we establish, together with an index theory argument. As a consequence, these solutions always admit a symmetry group.

  11. Motivations for AdS/QCD from 10D supergravity solutions

    International Nuclear Information System (INIS)

    De Paula, Wayne

    2016-01-01

    We discuss some attempts for the construction of gravity duals of QCD-like theories. It is analysed some properties of solutions of 10D Type IIB supergravity theory that attempt to be dual to N= 1 gauge theories, in particular the solutions that belong to Papadoulos-Tseytlin ansatz. We argue that one could obtain 5D effective theories from 10d solutions and it motivates the use of phenomenological AdS/QCD models. (paper)

  12. Superstrings on AdS4xCP3 from supergravity

    International Nuclear Information System (INIS)

    D'Auria, Riccardo; Trigiante, Mario; Fre, Pietro; Grassi, Pietro Antonio

    2009-01-01

    We derive from a general formulation of pure spinor string theory on type IIA backgrounds the specific form of the action for the AdS 4 xCP 3 background. We provide a complete geometrical characterization of the structure of the superfields involved in the action.

  13. Maslinic acid modulates secreted phospholipase A2-IIA (sPLA2-IIA ...

    Indian Academy of Sciences (India)

    Wei Hsum Yap

    2018-03-29

    Mar 29, 2018 ... Further analysis revealed that sPLA2-IIA only induced modest LDL oxidation and that inhibitory .... COX-2, was also reduced in primary human chondrocyte, primary rat .... oxidation (4.34 nmol MDA/mg protein) compared to native ..... rheumatoid fibroblast-like synoviocyte arachidonic acid meta- bolism.

  14. Scrutinizing supergravity models through neutrino telescopes

    CERN Document Server

    Gandhi, R; Nanopoulos, Dimitri V; Yuan, K; Zichichi, Antonino; Gandhi, Raj; Lopez, Jorge L.; Yuan, Kajia

    1994-01-01

    Galactic halo neutralinos ($\\chi$) captured by the Sun or Earth produce high-energy neutrinos as end-products of various annihilation modes. These neutrinos can travel from the Sun or Earth cores to the neighborhood of underground detectors (``neutrino telescopes") where they can interact and produce upwardly-moving muons. We compute these muon fluxes in the context of the minimal $SU(5)$ supergravity model, and the no-scale and dilaton $SU(5)\\times U(1)$ supergravity models. At present, with the Kamiokande 90\\% C.L. upper limits on the flux, only a small fraction of the parameter space of the $SU(5)\\times U(1)$ models is accessible for $m_\\chi\\sim m_{\\rm Fe}$, which in turn implies constraints for the lightest chargino mass around 100 GeV for a range of $\\tan\\beta$ values. We also delineate the regions of parameter space that would be accessible with the improvements of experimental sensitivity expected in the near future at Gran Sasso, Super-Kamiokande, and other facilities such as DUMAND and AMANDA, curren...

  15. Minimal N=4 topologically massive supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Kuzenko, Sergei M. [School of Physics M013, The University of Western Australia,35 Stirling Highway, Crawley W.A. 6009 (Australia); Novak, Joseph [Max-Planck-Institut für Gravitationsphysik, Albert-Einstein-Institut,Am Mühlenberg 1, D-14476 Golm (Germany); Sachs, Ivo [Arnold Sommerfeld Center for Theoretical Physics, Ludwig-Maximilians-Universität,Theresienstraße 37, D-80333 München (Germany)

    2017-03-21

    Using the superconformal framework, we construct a new off-shell model for N=4 topologically massive supergravity which is minimal in the sense that it makes use of a single compensating vector multiplet and involves no free parameter. As such, it provides a counterexample to the common lore that two compensating multiplets are required within the conformal approach to supergravity with eight supercharges in diverse dimensions. This theory is an off-shell N=4 supersymmetric extension of chiral gravity. All of its solutions correspond to non-conformally flat superspaces. Its maximally supersymmetric solutions include the so-called critical (4,0) anti-de Sitter superspace introduced in https://www.doi.org/10.1007/JHEP08(2012)024, and well as warped critical (4,0) anti-de Sitter superspaces. We also propose a dual formulation for the theory in which the vector multiplet is replaced with an off-shell hypermultiplet. Upon elimination of the auxiliary fields belonging to the hypermultiplet and imposing certain gauge conditions, the dual action reduces to the one introduced in https://www.doi.org/10.1103/PhysRevD.94.065028.

  16. New gauged N = 8, D = 4 supergravities

    International Nuclear Information System (INIS)

    Hull, C M

    2003-01-01

    New gaugings of four-dimensional N = 8 supergravity are constructed, including one which has a Minkowski space vacuum that preserves N = 2 supersymmetry and in which the gauge group is broken to SU(3) x U(1) 2 . Previous gaugings used the form of the ungauged action which is invariant under a rigid SL (8,R) symmetry and promoted a 28-dimensional subgroup (SO(8), SO(p, 8 - p) or the non-semi-simple contraction CSO(p, q, 8 - p - q)) to a local gauge group. Here, a dual form of the ungauged action is used which is invariant under SU*(8) instead of SL (8,R) and new theories are obtained by gauging 28-dimensional subgroups of SU*(8). The gauge groups are non-semi-simple and are different real forms of the CSO(2p, 8 - 2p) groups, denoted as CSO*(2p, 8 - 2p), and the new theories have a rigid SU(2) symmetry. The five-dimensional gauged N = 8 supergravities are dimensionally reduced to D = 4. The D = 5, SO(p, 6 - p) gauge theories reduce, after a duality transformation, to the D = 4, CSO(p, 6 - p, 2) gauging while the SO*(6) gauge theory reduces to the D = 4, CSO*(6, 2) gauge theory. The new theories are related to the old ones via an analytic continuation. The non-semi-simple gaugings can be dualized to forms with different gauge groups

  17. Vacua of maximal gauged D=3 supergravities

    International Nuclear Information System (INIS)

    Fischbacher, T; Nicolai, H; Samtleben, H

    2002-01-01

    We analyse the scalar potentials of maximal gauged three-dimensional supergravities which reveal a surprisingly rich structure. In contrast to maximal supergravities in dimensions D≥4, all these theories possess a maximally supersymmetric (N=16) ground state with negative cosmological constant Λ 2 gauged theory, whose maximally supersymmetric groundstate has Λ = 0. We compute the mass spectra of bosonic and fermionic fluctuations around these vacua and identify the unitary irreducible representations of the relevant background (super)isometry groups to which they belong. In addition, we find several stationary points which are not maximally supersymmetric, and determine their complete mass spectra as well. In particular, we show that there are analogues of all stationary points found in higher dimensions, among them are de Sitter (dS) vacua in the theories with noncompact gauge groups SO(5, 3) 2 and SO(4, 4) 2 , as well as anti-de Sitter (AdS) vacua in the compact gauged theory preserving 1/4 and 1/8 of the supersymmetries. All the dS vacua have tachyonic instabilities, whereas there do exist nonsupersymmetric AdS vacua which are stable, again in contrast to the D≥4 theories

  18. Nonlinear self-duality and supergravity

    International Nuclear Information System (INIS)

    Kuzenko, Sergei M.; McCarthy, Shane A.

    2003-01-01

    The concept of self-dual supersymmetric nonlinear electrodynamics is generalized to a curved superspace of N=1 supergravity, for both the old minimal and the new minimal versions of N=1 supergravity. We derive the self-duality equation, which has to be satisfied by the action functional of any U(1) duality invariant model of a massless vector multiplet, and construct a family of self-dual nonlinear models. This family includes a curved superspace extension of the N=1 super Born-Infeld action. The supercurrent and supertrace in such models are proved to be duality invariant. The most interesting and unexpected result is that the requirement of nonlinear self-duality yields nontrivial couplings of the vector multiplet to Kaehler sigma models. We explicitly derive the couplings to general Kaehler sigma models in the case when the matter chiral multiplets are inert under the duality rotations, and more specifically to the dilaton-axion chiral multiplet when the group of duality rotations is enhanced to SL(2,R). (author)

  19. Gauged supergravities from M-theory reductions

    Science.gov (United States)

    Katmadas, Stefanos; Tomasiello, Alessandro

    2018-04-01

    In supergravity compactifications, there is in general no clear prescription on how to select a finite-dimensional family of metrics on the internal space, and a family of forms on which to expand the various potentials, such that the lower-dimensional effective theory is supersymmetric. We propose a finite-dimensional family of deformations for regular Sasaki-Einstein seven-manifolds M 7, relevant for M-theory compactifications down to four dimensions. It consists of integrable Cauchy-Riemann structures, corresponding to complex deformations of the Calabi-Yau cone M 8 over M 7. The non-harmonic forms we propose are the ones contained in one of the Kohn-Rossi cohomology groups, which is finite-dimensional and naturally controls the deformations of Cauchy-Riemann structures. The same family of deformations can be also described in terms of twisted cohomology of the base M 6, or in terms of Milnor cycles arising in deformations of M 8. Using existing results on SU(3) structure compactifications, we briefly discuss the reduction of M-theory on our class of deformed Sasaki-Einstein manifolds to four-dimensional gauged supergravity.

  20. The goldstino brane, the constrained superfields and matter in N=1 supergravity

    International Nuclear Information System (INIS)

    Bandos, Igor; Heller, Markus; Kuzenko, Sergei M.; Martucci, Luca; Sorokin, Dmitri

    2016-01-01

    We show that different (brane and constrained superfield) descriptions for the Volkov-Akulov goldstino coupled to N=1, D=4 supergravity with matter produce similar wide classes of models with spontaneously broken local supersymmetry and discuss the relation between the different formulations. As with the formulations with irreducible constrained superfields, the geometric goldstino brane approach has the advantage of being manifestly off-shell supersymmetric without the need to introduce auxiliary fields. It provides an explicit solution of the nilpotent superfield constraints and avoids issues with non-Gaussian integration of auxiliary fields. We describe general couplings of the supersymmetry breaking sector, including the goldstino and other non-supersymmetric matter, to supergravity and matter supermultiplets. Among various examples, we discuss a goldstino brane contribution to the gravitino mass term and the supersymmetrization of the anti-D3-brane contribution to the effective theory of type IIB warped flux compactifications.

  1. Fermion mass hierarchies in low-energy supergravity and superstring models

    International Nuclear Information System (INIS)

    Binetruy, P.

    1995-01-01

    We investigate the problem of the fermion mass hierarchy in supergravity models with flat directions of the scalar potential associated with some gauge singlet moduli fields. The low-energy Yukawa couplings are non-trivial homogeneous functions of the moduli and a geometric constraint between them plays, in a large class of models, a crucial role in generating hierarchies. Explicit examples are given for no-scale type supergravity models. The Yukawa couplings are dynamical variables at low energy, to be determined by a minimization process which amounts to fixing ratios of the moduli fields. The Minimal Supersymmetric Standard Model is studied and the constraints needed on the parameters in order to have a top quark much heavier than the other fermions are worked out. The bottom mass is explicitly computed and shown to be compatible with the experimental data for a large region of the parameter space. ((orig.))

  2. The goldstino brane, the constrained superfields and matter in N=1 supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Bandos, Igor [Department of Theoretical Physics, University of the Basque Country UPV/EHU,P.O. Box 644, 48080 Bilbao (Spain); IKERBASQUE, Basque Foundation for Science,48011, Bilbao (Spain); Heller, Markus [Dipartimento di Fisica e Astronomia “Galileo Galilei' , Università degli Studi di Padova,Via Marzolo 8, 35131 Padova (Italy); Institut für Theoretische Physik, Ruprecht-Karls-Universität,Philosophenweg 19, 69120 Heidelberg (Germany); Kuzenko, Sergei M. [School of Physics M013, The University of Western Australia35 Stirling Highway, Crawley W.A. 6009 (Australia); Martucci, Luca [Dipartimento di Fisica e Astronomia “Galileo Galilei' , Università degli Studi di Padova,Via Marzolo 8, 35131 Padova (Italy); INFN - Sezione di Padova,Via Marzolo 8, 35131 Padova (Italy); Sorokin, Dmitri [INFN - Sezione di Padova,Via Marzolo 8, 35131 Padova (Italy); Dipartimento di Fisica e Astronomia “Galileo Galilei' , Università degli Studi di Padova,Via Marzolo 8, 35131 Padova (Italy)

    2016-11-21

    We show that different (brane and constrained superfield) descriptions for the Volkov-Akulov goldstino coupled to N=1, D=4 supergravity with matter produce similar wide classes of models with spontaneously broken local supersymmetry and discuss the relation between the different formulations. As with the formulations with irreducible constrained superfields, the geometric goldstino brane approach has the advantage of being manifestly off-shell supersymmetric without the need to introduce auxiliary fields. It provides an explicit solution of the nilpotent superfield constraints and avoids issues with non-Gaussian integration of auxiliary fields. We describe general couplings of the supersymmetry breaking sector, including the goldstino and other non-supersymmetric matter, to supergravity and matter supermultiplets. Among various examples, we discuss a goldstino brane contribution to the gravitino mass term and the supersymmetrization of the anti-D3-brane contribution to the effective theory of type IIB warped flux compactifications.

  3. Chern-Simons supergravity plus matter near the boundary of AdS3

    International Nuclear Information System (INIS)

    Deger, N.S.; Kaya, A.; Sezgin, E.; Sundell, P.; Tanii, Y.

    2001-01-01

    We examine the boundary behaviour of the gauged N=(2,0) supergravity in D=3 coupled to an arbitrary number of scalar supermultiplets which parametrize a Kaehler manifold. In addition to the gravitational coupling constant, the model depends on two parameters, namely the cosmological constant and the size of the Kaehler manifold. It is shown that regular and irregular boundary conditions can be imposed on the matter fields depending on the size of the sigma model manifold. It is also shown that the super AdS transformations in the bulk produce the transformations of the N=(2,0) conformal supergravity and scalar multiplets on the boundary, containing fields with nonvanishing Weyl weights determined by the ratio of the sigma model and the gravitational coupling constants. Various types of (2,0) superconformal multiplets are found on the boundary and in one case the superconformal symmetry is shown to be realized in an unconventional way

  4. Towards a worldsheet description of N=8 supergravity

    International Nuclear Information System (INIS)

    Lipstein, Arthur; Schomerus, Volker

    2015-10-01

    In this note we address the worldsheet description of 4-dimensional N=8 supergravity using ambitwistors. After gauging an appropriate current algebra, we argue that the only physical vertex operators correspond to the N=8 supermultiplet. It has previously been shown that worldsheet correlators give rise to supergravity tree level scattering amplitudes. We extend this work by proposing a definition for genus-one amplitudes that passes several consistency checks such as exhibiting modular invariance and reproducing the expected infrared behavior of 1-loop supergravity amplitudes.

  5. Invariants for minimal conformal supergravity in six dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Butter, Daniel [Nikhef Theory Group,Science Park 105, 1098 XG Amsterdam (Netherlands); Kuzenko, Sergei M. [School of Physics M013, The University of Western Australia,35 Stirling Highway, Crawley W.A. 6009 (Australia); Novak, Joseph; Theisen, Stefan [Max-Planck-Institut für Gravitationsphysik, Albert-Einstein-Institut,Am Mühlenberg 1, D-14476 Golm (Germany)

    2016-12-15

    We develop a new off-shell formulation for six-dimensional conformal supergravity obtained by gauging the 6D N=(1,0) superconformal algebra in superspace. This formulation is employed to construct two invariants for 6D N=(1,0) conformal supergravity, which contain C{sup 3} and C◻C terms at the component level. Using a conformal supercurrent analysis, we prove that these exhaust all such invariants in minimal conformal supergravity. Finally, we show how to construct the supersymmetric F◻F invariant in curved superspace.

  6. Secretory Phospholipase A2-IIA and Cardiovascular Disease

    DEFF Research Database (Denmark)

    Holmes, Michael V; Simon, Tabassome; Exeter, Holly J

    2013-01-01

    This study sought to investigate the role of secretory phospholipase A2 (sPLA2)-IIA in cardiovascular disease.......This study sought to investigate the role of secretory phospholipase A2 (sPLA2)-IIA in cardiovascular disease....

  7. Secretory Phospholipase A(2)-IIA and Cardiovascular Disease

    NARCIS (Netherlands)

    Holmes, Michael V.; Simon, Tabassome; Exeter, Holly J.; Folkersen, Lasse; Asselbergs, Folkert W.; Guardiola, Montse; Cooper, Jackie A.; Palmen, Jutta; Hubacek, Jaroslav A.; Carruthers, Kathryn F.; Horne, Benjamin D.; Brunisholz, Kimberly D.; Mega, Jessica L.; Van Iperen, Erik P. A.; Li, Mingyao; Leusink, Maarten; Trompet, Stella; Verschuren, Jeffrey J. W.; Hovingh, G. Kees; Dehghan, Abbas; Nelson, Christopher P.; Kotti, Salma; Danchin, Nicolas; Scholz, Markus; Haase, Christiane L.; Rothenbacher, Dietrich; Swerdlow, Daniel I.; Kuchenbaecker, Karoline B.; Staines-Urias, Eleonora; Goel, Anuj; van 't Hooft, Ferdinand; Gertow, Karl; de Faire, Ulf; Panayiotou, Andrie G.; Tremoli, Elena; Baldassarre, Damiano; Veglia, Fabrizio; Holdt, Lesca M.; Beutner, Frank; Gansevoort, Ron T.; Navis, Gerjan J.; Mateo Leach, Irene; Breitling, Lutz P.; Brenner, Hermann; Thiery, Joachim; Dallmeier, Dhayana; Franco-Cereceda, Anders; Boer, Jolanda M. A.; Stephens, Jeffrey W.; Hofker, Marten H.; Tedgui, Alain; Hofman, Albert; Uitterlinden, Andre G.; Adamkova, Vera; Pitha, Jan; Onland-Moret, N. Charlotte; Cramer, Maarten J.; Nathoe, Hendrik M.; Spiering, Wilko; Klungel, Olaf H.; Kumari, Meena; Whincup, Peter H.; Morrow, David A.; Braund, Peter S.; Hall, Alistair S.; Olsson, Anders G.; Doevendans, Pieter A.; Trip, Mieke D.; Tobin, Martin D.; Hamsten, Anders; Watkins, Hugh; Koenig, Wolfgang; Nicolaides, Andrew N.; Teupser, Daniel; Day, Ian N. M.; Carlquist, John F.; Gaunt, Tom R.; Ford, Ian; Sattar, Naveed; Tsimikas, Sotirios; Schwartz, Gregory G.; Lawlor, Debbie A.; Morris, Richard W.; Sandhu, Manjinder S.; Poledne, Rudolf; Maitland-van der Zee, Anke H.; Khaw, Kay-Tee; Keating, Brendan J.; van der Harst, Pim; Price, Jackie F.; Mehta, Shamir R.; Yusuf, Salim; Witteman, Jaqueline C. M.; Franco, Oscar H.; Jukema, J. Wouter; de Knijff, Peter; Tybjaerg-Hansen, Anne; Rader, Daniel J.; Farrall, Martin; Samani, Nilesh J.; Kivimaki, Mika; Fox, Keith A. A.; Humphries, Steve E.; Anderson, Jeffrey L.; Boekholdt, S. Matthijs; Palmer, Tom M.; Eriksson, Per; Pare, Guillaume; Hingorani, Aroon D.; Sabatine, Marc S.; Mallat, Ziad; Casas, Juan P.; Talmud, Philippa J.

    2013-01-01

    Objectives This study sought to investigate the role of secretory phospholipase A(2) (sPLA(2))-IIA in cardiovascular disease. Background Higher circulating levels of sPLA(2)-IIA mass or sPLA(2) enzyme activity have been associated with increased risk of cardiovascular events. However, it is not

  8. Effects of starch synthase IIa gene dosage on grain, protein and starch in endosperm of wheat.

    Science.gov (United States)

    Konik-Rose, Christine; Thistleton, Jenny; Chanvrier, Helene; Tan, Ihwa; Halley, Peter; Gidley, Michael; Kosar-Hashemi, Behjat; Wang, Hong; Larroque, Oscar; Ikea, Joseph; McMaugh, Steve; Regina, Ahmed; Rahman, Sadequr; Morell, Matthew; Li, Zhongyi

    2007-11-01

    Starch synthases (SS) are responsible for elongating the alpha-1,4 glucan chains of starch. A doubled haploid population was generated by crossing a line of wheat, which lacks functional ssIIa genes on each genome (abd), and an Australian wheat cultivar, Sunco, with wild type ssIIa alleles on each genome (ABD). Evidence has been presented previously indicating that the SGP-1 (starch granule protein-1) proteins present in the starch granule in wheat are products of the ssIIa genes. Analysis of 100 progeny lines demonstrated co-segregation of the ssIIa alleles from the three genomes with the SGP-1 proteins, providing further evidence that the SGP-1 proteins are the products of the ssIIa genes. From the progeny lines, 40 doubled haploid lines representing the eight possible genotypes for SSIIa (ABD, aBD, AbD, ABd, abD, aBd, Abd, abd) were characterized for their grain weight, protein content, total starch content and starch properties. For some properties (chain length distribution, pasting properties, swelling power, and gelatinization properties), a progressive change was observed across the four classes of genotypes (wild type, single nulls, double nulls and triple nulls). However, for other grain properties (seed weight and protein content) and starch properties (total starch content, granule morphology and crystallinity, granule size distribution, amylose content, amylose-lipid dissociation properties), a statistically significant change only occurred for the triple nulls, indicating that all three genes had to be missing or inactive for a change to occur. These results illustrate the importance of SSIIa in controlling grain and starch properties and the importance of amylopectin fine structure in controlling starch granule properties in wheat.

  9. Inoenue-Wigner contraction and D = 2 + 1 supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Concha, P.K.; Rodriguez, E.K. [Universidad Adolfo Ibanez, Departamento de Ciencias, Facultad de Artes Liberales, Vina del Mar (Chile); Universidad Austral de Chile, Instituto de Ciencias Fisicas y Matematicas, Valdivia (Chile); Fierro, O. [Universidad Catolica de la Santisima Concepcion, Departamento de Matematica y Fisica Aplicadas, Concepcion (Chile)

    2017-01-15

    We present a generalization of the standard Inoenue-Wigner contraction by rescaling not only the generators of a Lie superalgebra but also the arbitrary constants appearing in the components of the invariant tensor. The procedure presented here allows one to obtain explicitly the Chern-Simons supergravity action of a contracted superalgebra. In particular we show that the Poincare limit can be performed to a D = 2 + 1 (p,q) AdS Chern-Simons supergravity in presence of the exotic form. We also construct a new three-dimensional (2,0) Maxwell Chern-Simons supergravity theory as a particular limit of (2,0) AdS-Lorentz supergravity theory. The generalization for N = p + q gravitinos is also considered. (orig.)

  10. New set of auxiliary fields for supergravity theories

    International Nuclear Information System (INIS)

    Oliveira Rivelles, V. de.

    1983-02-01

    A brief introduction on supersymmetry is given. The problems with the obtainment of the auxiliary fields in supergravity theories are discussed, after a short presentation of the supersymmetry algebra representations. (L.C.) [pt

  11. Tensor calculus for the vector multiplet coupled to supergravity

    International Nuclear Information System (INIS)

    Stelle, K.S.

    1978-01-01

    An invariant coupling of a local vector multiplet to supergravity is constructed in analogy with the D term invariant of global supersymmetry. The rules for combining local vector and chiral scalar multiplets of opposite chirality are given. (Auth.)

  12. The electroweak phase transition in minimal supergravity models

    CERN Document Server

    Nanopoulos, Dimitri V

    1994-01-01

    We have explored the electroweak phase transition in minimal supergravity models by extending previous analysis of the one-loop Higgs potential to include finite temperature effects. Minimal supergravity is characterized by two higgs doublets at the electroweak scale, gauge coupling unification, and universal soft-SUSY breaking at the unification scale. We have searched for the allowed parameter space that avoids washout of baryon number via unsuppressed anomalous Electroweak sphaleron processes after the phase transition. This requirement imposes strong constraints on the Higgs sector. With respect to weak scale baryogenesis, we find that the generic MSSM is {\\it not} phenomenologically acceptable, and show that the additional experimental and consistency constraints of minimal supergravity restricts the mass of the lightest CP-even Higgs even further to $m_h\\lsim 32\\GeV$ (at one loop), also in conflict with experiment. Thus, if supergravity is to allow for baryogenesis via any other mechanism above the weak...

  13. N=2 supergravity in superspace and the BRS symmetry

    International Nuclear Information System (INIS)

    Kachkachi, M.; Lhallabi, T.

    1989-07-01

    The quantum N = 2 Einstein supergravity action is constructed by requiring the BRS symmetry. This latter is derived by the use of the distorted horizontality conditions in the curved N = 2 harmonic superspace. (author). 16 refs

  14. New compactifications in seven and eleven dimensional supergravity theories

    International Nuclear Information System (INIS)

    Pernici, M.; Sezgin, E.

    1984-08-01

    It is found that the N=4 gauged supergravity in d=7 spontaneously compactifies on direct product of anti-deSitter space (AdS) with a 3-sphere (non-supersymmetric: N=0), or with 3-hyperboloid (N=2). Similarly the N=2 gauged supergravity in d=7 compactifies on AdSxH 3 (N=1). The possibility of σ-model induced compactification of ungauged d=7 N=2 supergravity coupled to one vector multiplet on (Minkowski) 4 x Tear Drop x S 1 is discussed. The case of d=11 supergravity is also studied, and two new compactifications are found: AdS x non-Einstein squashed S 7 (n=0) and AdS x non-Einstein SU(2) bundle over CP 2 (N=0). (author)

  15. Sneutrino driven GUT inflation in supergravity

    International Nuclear Information System (INIS)

    Gonzalo, Tomás E.; Heurtier, Lucien; Moursy, Ahmad

    2017-01-01

    In this paper, we embed the model of flipped GUT sneutrino inflation — in a flipped SU(5) or SO(10) set up — developed by Ellis et al. in a supergravity framework. The GUT symmetry is broken by a waterfall which could happen at early or late stage of the inflationary period. The full field dynamics is thus studied in detail and these two main inflationary configurations are exposed, whose cosmological predictions are both in agreement with recent astrophysical measurements. The model has an interesting feature where the inflaton has natural decay channels to the MSSM particles allowed by the GUT gauge symmetry. Hence it can account for the reheating after the inflationary epoch.

  16. Sneutrino driven GUT inflation in supergravity

    Science.gov (United States)

    Gonzalo, Tomás E.; Heurtier, Lucien; Moursy, Ahmad

    2017-06-01

    In this paper, we embed the model of flipped GUT sneutrino inflation — in a flipped SU(5) or SO(10) set up — developed by Ellis et al. in a supergravity framework. The GUT symmetry is broken by a waterfall which could happen at early or late stage of the inflationary period. The full field dynamics is thus studied in detail and these two main inflationary configurations are exposed, whose cosmological predictions are both in agreement with recent astrophysical measurements. The model has an interesting feature where the inflaton has natural decay channels to the MSSM particles allowed by the GUT gauge symmetry. Hence it can account for the reheating after the inflationary epoch.

  17. Critical N = (1, 1) general massive supergravity

    Science.gov (United States)

    Deger, Nihat Sadik; Moutsopoulos, George; Rosseel, Jan

    2018-04-01

    In this paper we study the supermultiplet structure of N = (1, 1) General Massive Supergravity at non-critical and critical points of its parameter space. To do this, we first linearize the theory around its maximally supersymmetric AdS3 vacuum and obtain the full linearized Lagrangian including fermionic terms. At generic values, linearized modes can be organized as two massless and 2 massive multiplets where supersymmetry relates them in the standard way. At critical points logarithmic modes appear and we find that in three of such points some of the supersymmetry transformations are non-invertible in logarithmic multiplets. However, in the fourth critical point, there is a massive logarithmic multiplet with invertible supersymmetry transformations.

  18. Standard model fermions and N=8 supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Nicolai, Hermann [Max Planck Institute for Gravitational Physics (Albert Einstein Institute), Am Muehlenberg 1, Potsdam-Golm (Germany)

    2016-07-01

    In a scheme originally proposed by Gell-Mann, and subsequently shown to be realized at the SU(3) x U(1) stationary point of maximal gauged SO(8) supergravity, the 48 spin-1/2 fermions of the theory remaining after the removal of eight Goldstinos can be identified with the 48 quarks and leptons (including right-chiral neutrinos) of the Standard model, provided one identifies the residual SU(3) with the diagonal subgroup of the color group SU(3){sub c} and a family symmetry SU(3){sub f}. However, there remained a systematic mismatch in the electric charges by a spurion charge of ± 1/6. We here identify the ''missing'' U(1) that rectifies this mismatch, and that takes a surprisingly simple, though unexpected form, and show how it is related to the conjectured R symmetry K(E10) of M Theory.

  19. Gauged N=8 supergravity in five dimensions

    International Nuclear Information System (INIS)

    Guenaydin, M.; Romans, L.J.; Warner, N.P.

    1985-01-01

    We construct gauged N=8 supergravity theories in five dimensions. Instead of the twenty-seven vector fields of the ungauged theory, the gauged theories contain fifteen vector fields and twelve second-rank antisymmetric tensor fields satisfying self-dual field equations. The fifteen vector fields can be used to gauge any of the fifteen-dimensional semisimple subgroups of SL(6, R), sepcifically SO(p, 6-p) for p=0, 1, 2, 3. The gauged theories also have a physical global SU(1,1) symmetry which survives from the Esub(6(6)) symmetry of the ungauged theory. This SU(1, 1) for the SO(6) gauging is presumably related to that of the chiral N=2 theory in ten dimensions. In our formalism we maintain a composite local USp(8) symmetry analogous to SU(8) in four dimensions. (orig.)

  20. The effective supergravity of little string theory

    Science.gov (United States)

    Antoniadis, Ignatios; Delgado, Antonio; Markou, Chrysoula; Pokorski, Stefan

    2018-02-01

    In this work we present the minimal supersymmetric extension of the five-dimensional dilaton-gravity theory that captures the main properties of the holographic dual of little string theory. It is described by a particular gauging of N=2 supergravity coupled with one vector multiplet associated with the string dilaton, along the U(1) subgroup of SU(2) R-symmetry. The linear dilaton in the fifth coordinate solution of the equations of motion (with flat string frame metric) breaks half of the supersymmetries to N=1 in four dimensions. Interest in the linear dilaton model has lately been revived in the context of the clockwork mechanism, which has recently been proposed as a new source of exponential scale separation in field theory.

  1. The effective supergravity of little string theory

    Energy Technology Data Exchange (ETDEWEB)

    Antoniadis, Ignatios [Sorbonne Universite, CNRS, Laboratoire de Physique Theorique et Hautes Energies, LPTHE, Paris (France); University of Bern, Albert Einstein Center for Fundamental Physics, Institute for Theoretical Physics, Bern (Switzerland); Delgado, Antonio [University of Notre Dame, Department of Physics, Notre Dame, IN (United States); Markou, Chrysoula [Sorbonne Universite, CNRS, Laboratoire de Physique Theorique et Hautes Energies, LPTHE, Paris (France); Pokorski, Stefan [University of Warsaw, Faculty of Physics, Institute of Theoretical Physics, Warsaw (Poland)

    2018-02-15

    In this work we present the minimal supersymmetric extension of the five-dimensional dilaton-gravity theory that captures the main properties of the holographic dual of little string theory. It is described by a particular gauging of N = 2 supergravity coupled with one vector multiplet associated with the string dilaton, along the U(1) subgroup of SU(2) R-symmetry. The linear dilaton in the fifth coordinate solution of the equations of motion (with flat string frame metric) breaks half of the supersymmetries to N = 1 in four dimensions. Interest in the linear dilaton model has lately been revived in the context of the clockwork mechanism, which has recently been proposed as a new source of exponential scale separation in field theory. (orig.)

  2. Linearized supergravity with a dynamical preferred frame

    CERN Document Server

    Marakulin, Arthur

    2016-01-01

    We study supersymmetric extension of the Einstein-aether gravitational model where local Lorentz invariance is broken down to the subgroup of spatial rotations by a vacuum expectation value of a timelike vector field. By restricting to the level of linear perturbations around Lorentz-violating vacuum and using the superfield formalism we construct the most general action invariant under the linearized supergravity transformations. We show that, unlike its non-supersymmetric counterpart, the model contains only a single free dimensionless parameter, besides the usual dimensionful gravitational coupling. This makes the model highly predictive. An analysis of the spectrum of physical excitations reveal superluminal velocity of gravitons. The latter property leads to the extension of the gravitational multiplet by additional fermonic and bosonic states with helicities $\\pm 3/2$ and $\\pm 1$. We outline the observational constraints on the model following from its low-energy phenomenology.

  3. (Super-)Gravities of a different sort

    International Nuclear Information System (INIS)

    Edelstein, Jose D; Zanelli, Jorge

    2006-01-01

    We review the often forgotten fact that gravitation theories invariant under local de Sitter, anti-de Sitter or Poincare transformations can be constructed in all odd dimensions. These theories belong to the Chern-Simons family and are particular cases of the so-called Lovelock gravities, constructed as the dimensional continuations of the lower dimensional Euler classes. The supersymmetric extensions of these theories exist for the AdS and Poincare groups, and the fields are components of a single connection for the corresponding Lie algebras. In 11 dimensions these supersymmetric theories are gauge theories for the osp(1/32) and the M algebra, respectively. The relation between these new supergravities and the standard theories, as well as some of their dynamical features are also discussed

  4. Higher derivative corrections to BPS black hole attractors in 4d gauged supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Hristov, Kiril [Institute for Nuclear Research and Nuclear Energy, Bulgarian Academy of Sciences, Tsarigradsko Chaussee 72, 1784 Sofia (Bulgaria); Katmadas, Stefanos [Dipartimento di Fisica, Università di Milano-Bicocca,I-20126 Milano (Italy); INFN, Sezione di Milano-Bicocca,I-20126 Milano (Italy); Lodato, Ivano [Department of Physics, IISER Pune,Homi Bhaba Road, Pashan, Pune (India)

    2016-05-30

    We analyze BPS black hole attractors in 4d gauged supergravity in the presence of higher derivative supersymmetric terms, including a Weyl-squared-type action, and determine the resulting corrections to the Bekenstein-Hawking entropy. The near-horizon geometry AdS{sub 2}×S{sup 2} (or other Riemann surface) preserves half of the supercharges in N=2 supergravity with Fayet-Iliopoulos gauging. We derive a relation between the entropy and the black hole charges that suggests via AdS/CFT how subleading corrections contribute to the supersymmetric index in the dual microscopic picture. Depending on the model, the attractors are part of full black hole solutions with different asymptotics, such as Minkowski, AdS{sub 4}, and hvLif{sub 4}. We give explicit examples for each of the asymptotic cases and comment on the implications. Among other results, we find that the Weyl-squared terms spoil the exact two-derivative relation to non-BPS asymptotically flat black holes in ungauged supergravity.

  5. Supergravity tensor calculus in 5D from 6D

    International Nuclear Information System (INIS)

    Kugo, Taichiro; Ohashi, Keisuke

    2000-01-01

    Supergravity tensor calculus in five spacetime dimensions is derived by dimensional reduction from the d=6 superconformal tensor calculus. In particular, we obtain an off-shell hypermultiplet in 5D from the on-shell hypermultiplet in 6D. Our tensor calculus retains the dilatation gauge symmetry, so that it is a trivial gauge fixing to make the Einstein term canonical in a general matter-Yang-Mills-supergravity coupled system. (author)

  6. Quantum creation of the universe in N = 8 supergravity

    International Nuclear Information System (INIS)

    Goncharov, Yu.P.; Bytsenko, A.A.

    1988-01-01

    We discuss the possibility of quantum creation of an inflationary universe filled with the fields of maximal extended N = 8 supergravity. If the created universe has spatial topology (S 1 ) 3 and after the creation Starobinskii's inflationary scenario through the topological Casimir effect in N = 8 supergravity is realized, the probability of creation of such a universe can be estimated in the semiclassical approximation. The estimate shows that the creation of a universe with a more isotropic topology is more probable

  7. The structure of N = 2 supergravity in N = 1 superfields

    International Nuclear Information System (INIS)

    Awada, M.A.; Mokhtari, S.

    1985-01-01

    A formulation of N = 2 supergravity in N = 1 superspace is presented. The authors solve up to all orders the N = 2 supergravity constraints in terms of unconstrained N = 1 superfields. The structure of the N = 2 action in N = 1 superspace is examined. The proposed action coincides in the quadratic limit of the spin (3/2,1) matter fields with the action given by previous workers. (author)

  8. Structure of N = 2 supergravity in N = 1 superfields

    Energy Technology Data Exchange (ETDEWEB)

    Awada, M.A.; Mokhtari, S. (Imperial Coll. of Science and Technology, London (UK). Blackett Lab.)

    1985-01-01

    A formulation of N = 2 supergravity in N = 1 superspace is presented. The authors solve up to all orders the N = 2 supergravity constraints in terms of unconstrained N = 1 superfields. The structure of the N = 2 action in N = 1 superspace is examined. The proposed action coincides in the quadratic limit of the spin (3/2,1) matter fields with the action given by previous workers.

  9. Off shell N=1 supergravity theory in six dimensions

    International Nuclear Information System (INIS)

    Smith, A.W.

    1983-01-01

    The off shell N=1 supergravity theory in six dimensions shows beneath the extreme simplicity of theories in higher dimensions useful properties for the study of a unification of normal gauge theories with the supergravity theory via dimensional reduction and yields a geometrical interpretation for the quantum numbers of internal symmtries of the reduced theory. Furthermore this theory permits a better understanding of ultraviolet divergences than a theory in four dimensions. This six-dimensional supergravity theory is constructed here in the corresponding superspace the importance of which was clained otherwise because a precisely defined mathematical formalism for this exists: Differential geometry in the superspace. We establish constraining conditions for the torsion components and give a complete solution of the Bianchi identities. In the formulation of the conditions for the torsions exists a certain freedom, because different conditions lead to the same solution. Therefore only the analysis of the Bianchi identities will show wether the conditions are too restrictive or not. Furthermore the dimensional reduction of D=6 to the four-dimensional space-time is performed. We show here that the reduced theory yields the conformal N=2 supergravity theory. In the last part of this thesis a Langrangian is presented by which the supergravity is coupled to a matter multiplet. In the analysis of the supersymmetry transformations of the component fields we see that the matter multiplet cannot be consistently brought to vanish. That means that a pure supergravity theory cannot be written manifestly Lorentz covariant. (orig.) [de

  10. Tanshinone IIA increases the bystander effect of herpes simplex virus thymidine kinase/ganciclovir gene therapy via enhanced gap junctional intercellular communication.

    Directory of Open Access Journals (Sweden)

    Jianyong Xiao

    Full Text Available The bystander effect is an intriguing phenomenon by which adjacent cells become sensitized to drug treatment during gene therapy with herpes simplex virus thymidine kinase/ganciclovir (HSV-tk/GCV. This effect is reported to be mediated by gap junctional intercellular communication (GJIC, and therefore, we postulated that upregulation of genes that facilitate GJIC may enhance the HSV-tk/GCV bystander effect. Previous findings have shown Tanshinone IIA (Tan IIA, a chemical substance derived from a Chinese medicine herb, promotes the upregulation of the connexins Cx26 and Cx43 in B16 cells. Because gap junctions are formed by connexins, we hypothesized that Tan IIA might increase GJIC. Our results show that Tan IIA increased GJIC in B16 melanoma cells, leading to more efficient GCV-induced bystander killing in cells stably expressing HSV-tk. Additionally, in vivo experiments demonstrated that tumors in mice with 10% HSV-tk positive B16 cells and 90% wild-type B16 cells became smaller following treatment with the combination of GCV and Tan IIA as compared to GCV or Tan IIA alone. These data demonstrate that Tan IIA can augment the bystander effect of HSV-tk/GCV system through increased gap junction coupling, which adds strength to the promising strategy that develops connexins inducer to potentiate the effects of suicide gene therapy.

  11. Tanshinone IIA suppresses FcεRI-mediated mast cell signaling and anaphylaxis by activation of the Sirt1/LKB1/AMPK pathway.

    Science.gov (United States)

    Li, Xian; Park, Soon Jin; Jin, Fansi; Deng, Yifeng; Yang, Ju Hye; Chang, Jae-Hoon; Kim, Dong-Young; Kim, Jung-Ae; Lee, Youn Ju; Murakami, Makoto; Son, Kun Ho; Chang, Hyeun Wook

    2018-06-01

    AMP-activated protein kinase (AMPK) and its upstream mediators liver kinase B1 (LKB1) and sirtuin 1 (Sirt1) are generally known as key regulators of metabolism. We have recently reported that the AMPK pathway negatively regulates mast cell activation and anaphylaxis. Tanshinone IIA (Tan IIA), an active component of Salvia miltiorrhiza extract that is currently used for the treatment of cardiovascular and cerebrovascular diseases, shows anti-diabetic activity and improves insulin resistance in db/db mice through activation of AMPK. The aim of this study was to evaluate the anti-allergic activity of Tan IIA in vivo and to investigate the underlying mechanism in vitro in the context of AMPK signaling. The anti-allergic effect of Tan IIA was evaluated using mouse bone marrow-derived mast cells (BMMCs) from AMPKα2 -/- or Sirt1 -/- mice, or BMMCs transfected with siRNAs specific for AMPKα2, LKB1, or Sirt1. AMPKα2 -/- and Sirt1 -/- mice were used to confirm the anti-allergic effect of Tan IIA in anaphylaxis in vivo. Tan IIA dose-dependently inhibited FcεRI-mediated degranulation and production of eicosanoids and cytokines in BMMCs. These inhibitory effects were diminished by siRNA-mediated knockdown or genetic deletion of AMPKα2 or Sirt1. Moreover, Tan IIA inhibited a mast cell-mediated local passive anaphylactic reaction in wild-type mice, but not in AMPKα2 -/- or Sirt1 -/- mice. In conclusion, Tan IIA suppresses FcεRI-mediated mast cell activation and anaphylaxis through activation of the inhibitory Sirt1-LKB1-AMPK pathway. Thus, Tan IIA may be useful as a new therapeutic agent for mast cell-mediated allergic diseases. Copyright © 2018 Elsevier Inc. All rights reserved.

  12. On minimal coupling of the ABC-superparticle to supergravity background

    OpenAIRE

    Galajinsky, A. V.; Gitman, D. M.

    1998-01-01

    By rigorous application of the Hamiltonian methods we show that the ABC-formulation of the Siegel superparticle admits consistent minimal coupling to external supergravity. The consistency check proves to involve all the supergravity constraints.

  13. A complete solution of the Bianchi identities in superspace with supergravity constraints

    International Nuclear Information System (INIS)

    Grimm, R.; Wess, J.; Zumino, B.

    1979-01-01

    A short discussion of the superspace formulation of supergravity is given and the Bianchi identities are derived. The supergravity constraints are imposed and the identities are solved in terms of superfields and their covariant derivatives. (Auth.)

  14. Session II-A. Site characterization

    International Nuclear Information System (INIS)

    McIntosh, W.

    1981-01-01

    Section II-A on Site Characterization consists of the following papers which describe the progress made during the past fiscal year toward identifying sites for high-level radioactive waste repositories in deep geologic formations: (1) progress in expanded studies for repository sites; (2) evaluation of geologic and hydrologic characteristics in the Basin and Range Province relative to high-level nuclear waste disposal; (3) siting progress: Permian region; (4) Paradox Basin site exploration: a progress report; (5) progress toward recommending a salt site for an exploratory shaft; (6) status of geologic investigations for nuclear waste disposal at the Nevada Test Site; (7) geohydrologic investigation of the Hanford Site, Washington: basalt waste isolation project. Highlights include: expanding studies in crystalline rocks, both in the Appalachian and Lake Superior regions; laying the ground work with the states in the Basin and Range Province to kick off a joint USGS-state province study; narrowing areas of the Permian and Paradox bedded salt regions to a few promising locations; issuing a Gulf Coast Salt Dome Evaluation report (ONWI-109) for public review and comment; narrowing the Nevada Test Site area and Hanford Site area to locations for detailed site investigations and exploratory shafts; progress in developing the subseabed and space disposals alternatives

  15. R4 terms in supergravities via T -duality constraint

    Science.gov (United States)

    Razaghian, Hamid; Garousi, Mohammad R.

    2018-05-01

    It has been speculated in the literature that the effective actions of string theories at any order of α' should be invariant under the Buscher rules plus their higher covariant-derivative corrections. This may be used as a constraint to find effective actions at any order of α', in particular, the metric, the B -field, and the dilaton couplings in supergravities at order α'3 up to an overall factor. For the simple case of zero B -field and diagonal metric in which we have done the calculations explicitly, we have found that the constraint fixes almost all of the seven independent Riemann curvature couplings. There is only one term which is not fixed, because when metric is diagonal, the reduction of two R4 terms becomes identical. The Riemann curvature couplings that the T -duality constraint produces for both type II and heterotic theories are fully consistent with the existing couplings in the literature which have been found by the S-matrix and by the sigma-model approaches.

  16. Summing up D-instantons in N=2 supergravity

    International Nuclear Information System (INIS)

    Ketov, Sergei V.

    2003-01-01

    The non-perturbative quantum geometry of the universal hypermultiplet (UH) is investigated in N=2 supergravity. The UH low-energy effective action is given by the four-dimensional quaternionic non-linear sigma-model having an U(1)xU(1) isometry. The UH metric is governed by the single real pre-potential that is an eigenfunction of the Laplacian in the hyperbolic plane. We calculate the classical pre-potential corresponding to the standard (Ferrara-Sabharwal) metric of the UH arising in the Calabi-Yau compactification of type-II superstrings. The non-perturbative quaternionic metric, describing the D-instanton contributions to the UH geometry, is found by requiring the SL(2,Z) modular invariance of the UH pre-potential. The pre-potential found is unique, while it coincides with the D-instanton function of Green and Gutperle, given by the order-3/2 Eisenstein series. As a by-product, we prove cluster decomposition of D-instantons in curved spacetime. The non-perturbative UH pre-potential interpolates between the perturbative (large CY volume) region and the superconformal (Landau-Ginzburg) region in the UH moduli space. We also calculate a non-perturbative scalar potential in the hyper-Kaehler limit, when an abelian isometry of the UH metric is gauged in the presence of D-instantons

  17. Constraints on modular inflation in supergravity and string theory

    International Nuclear Information System (INIS)

    Covi, L.; Palma, G.A.; Gomez-Reino, M.; Gross, C.; Louis, J.; Hamburg Univ.; Scrucca, C.A.

    2008-05-01

    We perform a general algebraic analysis on the possibility of realising slow-roll inflation in the moduli sector of string models. This problem turns out to be very closely related to the characterisation of models admitting metastable vacua with non-negative cosmological constant. In fact, we show that the condition for the existence of viable inflationary trajectories is a deformation of the condition for the existence of metastable de Sitter vacua. This condition depends on the ratio between the scale of inflation and the gravitino mass and becomes stronger as this parameter grows. After performing a general study within arbitrary supergravity models, we analyse the implications of our results in several examples. More concretely, in the case of heterotic and orientifold string compactifications on a Calabi-Yau in the large volume limit we show that there may exist fully viable models, allowing both for inflation and stabilisation. Additionally, we show that subleading corrections breaking the no-scale property shared by these models always allow for slow-roll inflation but with an inflationary scale suppressed with respect to the gravitino scale. A scale of inflation larger than the gravitino scale can also be achieved under more restrictive circumstances and only for certain types of compactifications. (orig.)

  18. Summing up D-instantons in N=2 supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Ketov, Sergei V. E-mail: ketov@phys.metro-u.ac.jp

    2003-01-20

    The non-perturbative quantum geometry of the universal hypermultiplet (UH) is investigated in N=2 supergravity. The UH low-energy effective action is given by the four-dimensional quaternionic non-linear sigma-model having an U(1)xU(1) isometry. The UH metric is governed by the single real pre-potential that is an eigenfunction of the Laplacian in the hyperbolic plane. We calculate the classical pre-potential corresponding to the standard (Ferrara-Sabharwal) metric of the UH arising in the Calabi-Yau compactification of type-II superstrings. The non-perturbative quaternionic metric, describing the D-instanton contributions to the UH geometry, is found by requiring the SL(2,Z) modular invariance of the UH pre-potential. The pre-potential found is unique, while it coincides with the D-instanton function of Green and Gutperle, given by the order-3/2 Eisenstein series. As a by-product, we prove cluster decomposition of D-instantons in curved spacetime. The non-perturbative UH pre-potential interpolates between the perturbative (large CY volume) region and the superconformal (Landau-Ginzburg) region in the UH moduli space. We also calculate a non-perturbative scalar potential in the hyper-Kaehler limit, when an abelian isometry of the UH metric is gauged in the presence of D-instantons.

  19. Japanese contributions to IAEA INTOR workshop, phase IIA

    International Nuclear Information System (INIS)

    Naruse, Yuji; Hiraoka, Toru; Tanaka, Kichizo

    1982-11-01

    Tritium breeding blanket is incorporated in the INTOR design based on economic and tritium availability considerations. In Phase IIA, critical issues on 'Tritium', which were identified during the Phase I Workshop, were investigated. Main objectives of Phase IIA are to develop a tritium breeding blanket and to evaluate tritium containment. Data base assessments of tritium containment were made. The design of the tritium breeding blanket was also revised. (author)

  20. Inhibitory effect of tanshinone IIA on rat hepatic stellate cells.

    Directory of Open Access Journals (Sweden)

    Ya-Wei Liu

    Full Text Available Anti-inflammation via inhibition of NF-κB pathways in hepatic stellate cells (HSCs is one therapeutic approach to hepatic fibrosis. Tanshinone IIA (C19H18O3, Tan IIA is a lipophilic diterpene isolated from Salvia miltiorrhiza Bunge, with reported anti-inflammatory activity. We tested whether Tan IIA could inhibit HSC activation.The cell line of rat hepatic stellate cells (HSC-T6 was stimulated with lipopolysaccharide (LPS (100 ng/ml. Cytotoxicity was assessed by MTT assay. HSC-T6 cells were pretreated with Tan IIA (1, 3 and 10 µM, then induced by LPS (100 ng/ml. NF-κB activity was evaluated by the luciferase reporter gene assay. Western blotting analysis was performed to measure NF-κB-p65, and phosphorylations of MAPKs (ERK, JNK, p38. Cell chemotaxis was assessed by both wound-healing assay and trans-well invasion assay. Quantitative real-time PCR was used to detect gene expression in HSC-T6 cells.All concentrations of drugs showed no cytotoxicity against HSC-T6 cells. LPS stimulated NF-κB luciferase activities, nuclear translocation of NF-κB-p65, and phosphorylations of ERK, JNK and p38, all of which were suppressed by Tan IIA. In addition, Tan IIA significantly inhibited LPS-induced HSCs chemotaxis, in both wound-healing and trans-well invasion assays. Moreover, Tan IIA attenuated LPS-induced mRNA expressions of CCL2, CCL3, CCL5, IL-1β, TNF-α, IL-6, ICAM-1, iNOS, and α-SMA in HSC-T6 cells.Our results demonstrated that Tan IIA decreased LPS-induced HSC activation.

  1. Supergravity on an Atiyah-Hitchin base

    International Nuclear Information System (INIS)

    Stotyn, Sean; Mann, R.B.

    2008-01-01

    We construct solutions to five dimensional minimal supergravity using an Atiyah-Hitchin base space. In examining the structure of solutions we show that they generically contain a singularity either on the Atiyah-Hitchin bolt or at larger radius where there is a singular solitonic boundary. However for most points in parameter space the solution exhibits a velocity of light surface (analogous to what appears in a Goedel space-time) that shields the singularity. For these solutions, all closed time-like curves are causally disconnected from the rest of the space-time in that they exist within the velocity of light surface, which null geodesics are unable to cross. The singularities in these solutions are thus found to be hidden behind the velocity of light surface and so are not naked despite the lack of an event horizon. Outside of this surface the space-time is geodesically complete, asymptotically flat and can be arranged so as not to contain closed time-like curves at infinity. The rest of parameter space simply yields solutions with naked singularities.

  2. Supersymmetry, superfields and supergravity: An introduction

    International Nuclear Information System (INIS)

    Srivastava, P.P.

    1986-01-01

    This book is a self-contained introduction to the subject of supersymmetry. The algebras of supersymmetry and the R-symmetry generators are explained using a simple field theory model. The realisations of this algebra on one-particle states and on a supermultiplet of component fields are then discussed. There is a detailed description of the Wess-Zumino model, with discussion of the realisation of R-symmetry and supermultiplets of currents and anomalies. Detailed treatment of the realisation of the algebra on superspace and superfields is applied to the Yang-Mills theory in interaction with matter. The possibility of spontaneously broken symmetries is introduced before non-Abelian supersymmetric gauge theories are constructed. Superfield propagators are derived as the Green functions of the corresponding equations of motion and the power of superfield perturbation theory is illustrated. Finally local supersymmetry and the supergravity Lagrangian are introduced with a discussion of gravity-induced supersymmetry breaking and the super-Higgs effect. Emphasis is placed on developing a physical understanding of the mathematical formalism and numerous problems are included to help develop the reader's understanding

  3. A counterselection method for Lactococcus lactis genome editing based on class IIa bacteriocin sensitivity.

    Science.gov (United States)

    Wan, Xing; Usvalampi, Anne M; Saris, Per E J; Takala, Timo M

    2016-11-01

    In this paper, we present a new counterselection method for deleting fragments from Lactococcus lactis chromosome. The method uses a non-replicating plasmid vector, which integrates into the chromosome and makes the cell sensitive to bacteriocins. The integration vector carries pUC ori functional in Escherichia coli but not in L. lactis, an erythromycin resistance gene for selecting single crossover integrants, and two fragments from L. lactis chromosome for homologous recombinations. In addition, the integration vector is equipped with the Listeria monocytogenes gene mptC encoding the mannose-phosphotransferase system component IIC, the receptor for class IIa bacteriocins. Expression of mptC from the integration vector renders the naturally resistant L. lactis sensitive to class IIa bacteriocins. This sensitivity is then used to select the double crossover colonies on bacteriocin agar. Only the cells which have regained the endogenous bacteriocin resistance through the loss of the mptC plasmid will survive. The colonies carrying the desired deletion can then be distinguished from the wild-type revertants by PCR. By using the class IIa bacteriocins leucocin A, leucocin C or pediocin AcH as the counterselective agents, we deleted 22- and 33-kb chromosomal fragments from the wild-type nisin producing L. lactis strain N8. In conclusion, this counterselection method presented here is a convenient, efficient and inexpensive technique to generate successive deletions in L. lactis chromosome.

  4. On-shell diagrams for N=8 supergravity amplitudes

    Energy Technology Data Exchange (ETDEWEB)

    Heslop, Paul; Lipstein, Arthur E. [Department of Mathematical Sciences, Durham University,Lower Mountjoy, Stockton Road, Durham, DH1 3LE (United Kingdom)

    2016-06-10

    We define recursion relations for N=8 supergravity amplitudes using a generalization of the on-shell diagrams developed for planar N=4 super-Yang-Mills. Although the recursion relations generically give rise to non-planar on-shell diagrams, we show that at tree-level the recursion can be chosen to yield only planar diagrams, the same diagrams occurring in the planar N=4 theory. This implies non-trivial identities for non-planar diagrams as well as interesting relations between the N=4 and N=8 theories. We show that the on-shell diagrams of N=8 supergravity obey equivalence relations analogous to those of N=4 super-Yang-Mills, and we develop a systematic algorithm for reading off Grassmannian integral formulae directly from the on-shell diagrams. We also show that the 1-loop 4-point amplitude of N=8 supergravity can be obtained from on-shell diagrams.

  5. Brane induced supersymmetry breaking and de Sitter supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Bandos, Igor [Department of Theoretical Physics, University of the Basque Country UPV/EHU, P.O. Box 644, 48080 Bilbao (Spain); IKERBASQUE, Basque Foundation for Science, 48011 Bilbao (Spain); Martucci, Luca [Dipartimento di Fisica e Astronomia “Galileo Galilei”, Università di Padova, Via Marzolo 8, 35131 Padova (Italy); I.N.F.N. Sezione di Padova, Via Marzolo 8, 35131 Padova (Italy); Sorokin, Dmitri [I.N.F.N. Sezione di Padova, Via Marzolo 8, 35131 Padova (Italy); Dipartimento di Fisica e Astronomia “Galileo Galilei”, Università di Padova, Via Marzolo 8, 35131 Padova (Italy); Tonin, Mario [Dipartimento di Fisica e Astronomia “Galileo Galilei”, Università di Padova, Via Marzolo 8, 35131 Padova (Italy); I.N.F.N. Sezione di Padova, Via Marzolo 8, 35131 Padova (Italy)

    2016-02-12

    We obtain a four-dimensional supergravity with spontaneously broken supersymmetry allowing for de Sitter vacua by coupling a superspace action of minimal N=1, D=4 supergravity to a locally supersymmetric generalization of the Volkov-Akulov goldstino action describing the dynamics of a space-filling non-BPS 3-brane in N=1, D=4 superspace. To the quadratic order in the goldstino field the obtained action coincides with earlier constructions of supergravities with nilpotent superfields, while matching the higher-order contributions will require a non-linear redefinition of fields. In the unitary gauge, in which the goldstino field is set to zero, the action coincides with that of Volkov and Soroka. We also show how a nilpotency constraint on a chiral curvature superfield emerges in this formulation.

  6. Absence of U(1) anomalous superamplitudes in N≥5 supergravities

    Energy Technology Data Exchange (ETDEWEB)

    Freedman, Daniel Z. [Stanford Institute for Theoretical Physics and Department of Physics, Stanford University,Stanford, CA 94305 (United States); Center for Theoretical Physics and Department of Mathematics,Massachusetts Institute of Technology,Cambridge, MA 02139 (United States); Kallosh, Renata; Murli, Divyanshu [Stanford Institute for Theoretical Physics and Department of Physics, Stanford University,Stanford, CA 94305 (United States); Proeyen, Antoine Van [KU Leuven, Institute for Theoretical Physics,Celestijnenlaan 200D, B-3001, Leuven (Belgium); Yamada, Yusuke [Stanford Institute for Theoretical Physics and Department of Physics, Stanford University,Stanford, CA 94305 (United States)

    2017-05-12

    We list all potential candidates for U(1) anomalous non-local 1-loop 4-point amplitudes and higher loop UV divergences in N≥5 supergravities. The relevant chiral superinvariants are constructed from linearized chiral superfields and define the corresponding superamplitudes. The anomalous amplitudes, of the kind present in N=4, are shown to be absent in N≥5. In N=6 supergravity the result is deduced from the double-copy (N=4){sub YM}×(N=2){sub YM} model, whereas in N=5,8 the result on absence of anomalous amplitudes is derived in supergravities as well as in the (N=4){sub YM}×(N−4){sub YM} double-copy models.

  7. Two-Field Analysis of No-Scale Supergravity Inflation

    CERN Document Server

    Ellis, John; Nanopoulos, Dimitri V; Olive, Keith A

    2015-01-01

    Since the building-blocks of supersymmetric models include chiral superfields containing pairs of effective scalar fields, a two-field approach is particularly appropriate for models of inflation based on supergravity. In this paper, we generalize the two-field analysis of the inflationary power spectrum to supergravity models with arbitrary K\\"ahler potential. We show how two-field effects in the context of no-scale supergravity can alter the model predictions for the scalar spectral index $n_s$ and the tensor-to-scalar ratio $r$, yielding results that interpolate between the Planck-friendly Starobinsky model and BICEP2-friendly predictions. In particular, we show that two-field effects in a chaotic no-scale inflation model with a quadratic potential are capable of reducing $r$ to very small values $\\ll 0.1$. We also calculate the non-Gaussianity measure $f_{\\rm NL}$, finding that is well below the current experimental sensitivity.

  8. On the consistency of classical and quantum supergravity theories

    Energy Technology Data Exchange (ETDEWEB)

    Hack, Thomas-Paul [II. Institute for Theoretical Physics, University of Hamburg (Germany); Makedonski, Mathias [Department of Mathematical Sciences, University of Copenhagen (Denmark); Schenkel, Alexander [Department of Stochastics, University of Wuppertal (Germany)

    2012-07-01

    It is known that pure N=1 supergravity in d=4 spacetime dimensions is consistent at a classical and quantum level, i.e. that in a particular gauge the field equations assume a hyperbolic form - ensuring causal propagation of the degrees of freedom - and that the associated canonical quantum field theory satisfies unitarity. It seems, however, that it is yet unclear whether these properties persist if one considers the more general and realistic case of N=1, d=4 supergravity theories including arbitrary matter fields. We partially clarify the issue by introducing novel hyperbolic gauges for the gravitino field and proving that they commute with the resulting equations of motion. Moreover, we review recent partial results on the unitarity of these general supergravity theories and suggest first steps towards a comprehensive unitarity proof.

  9. The component structure of conformal supergravity invariants in six dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Butter, Daniel [Nikhef Theory Group,Science Park 105, 1098 XG Amsterdam (Netherlands); George and Cynthia Woods Mitchell Institute for Fundamental Physics and Astronomy,Texas A& M University,College Station, TX 77843 (United States); Novak, Joseph [Max-Planck-Institut für Gravitationsphysik, Albert-Einstein-Institut, Am Mühlenberg 1, D-14476 Golm (Germany); Tartaglino-Mazzucchelli, Gabriele [Instituut voor Theoretische Fysica, KU Leuven,Celestijnenlaan 200D, B-3001 Leuven (Belgium)

    2017-05-24

    In the recent paper https://arxiv.org/abs/1606.02921, the two invariant actions for 6D N=(1,0) conformal supergravity were constructed in superspace, corresponding to the supersymmetrization of C{sup 3} and C◻C. In this paper, we provide the translation from superspace to the component formulation of superconformal tensor calculus, and we give the full component actions of these two invariants. As a second application, we build the component form for the supersymmetric F◻F action coupled to conformal supergravity. Exploiting the fact that the N=(2,0) Weyl multiplet has a consistent truncation to N=(1,0), we then verify that there is indeed only a single N=(2,0) conformal supergravity invariant and reconstruct most of its bosonic terms by uplifting a certain linear combination of N=(1,0) invariants.

  10. Complex superspaces and prepotentials for N = 2 supergravity

    International Nuclear Information System (INIS)

    Sokatchev, E.

    1981-01-01

    A prepotential formulation of N=2 supergravity is constructed as a generalization of the non-minimal N=1 case. The non-minimal and minimal prepotential formulations of N=1 supergravity are briefly reviewed, the non-minimal case is then generalized to from the basis of the N=2 theory. The action of the Lorentz structure group is extracted from the transformation law of the spinar derivatives. Vielbeins and connections are defined and expressed in terms of the prepotentials. In evaluation of the torsion components the normal gauge technique is applied. The possibility of using the invariant volume of the chiral superspaces as an action for the N=2 supergravity is considered. (author)

  11. Nonmuscle myosin heavy chain IIA is a critical factor contributing to the efficiency of early infection of severe fever with thrombocytopenia syndrome virus.

    Science.gov (United States)

    Sun, Yinyan; Qi, Yonghe; Liu, Chenxuan; Gao, Wenqing; Chen, Pan; Fu, Liran; Peng, Bo; Wang, Haimin; Jing, Zhiyi; Zhong, Guocai; Li, Wenhui

    2014-01-01

    Severe fever with thrombocytopenia syndrome virus (SFTSV) is a novel phlebovirus in the Bunyaviridae family. Most patients infected by SFTSV present with fever and thrombocytopenia, and up to 30% die due to multiple-organ dysfunction. The mechanisms by which SFTSV enters multiple cell types are unknown. SFTSV contains two species of envelope glycoproteins, Gn (44.2 kDa) and Gc (56 kDa), both of which are encoded by the M segment and are cleaved from a precursor polypeptide (about 116 kDa) in the endoplasmic reticulum (ER). Gn fused with an immunoglobulin Fc tag at its C terminus (Gn-Fc) bound to multiple cells susceptible to the infection of SFTSV and blocked viral infection of human umbilical vein endothelial cells (HUVECs). Immunoprecipitation assays following mass spectrometry analysis showed that Gn binds to nonmuscle myosin heavy chain IIA (NMMHC-IIA), a cellular protein with surface expression in multiple cell types. Small interfering RNA (siRNA) knockdown of NMMHC-IIA, but not the closely related NMMHC-IIB or NMMHC-IIC, reduced SFTSV infection, and NMMHC-IIA specific antibody blocked infection by SFTSV but not other control viruses. Overexpression of NMMHC-IIA in HeLa cells, which show limited susceptivity to SFTSV, markedly enhanced SFTSV infection of the cells. These results show that NMMHC-IIA is critical for the cellular entry of SFTSV. As NMMHC-IIA is essential for the normal functions of platelets and human vascular endothelial cells, it is conceivable that NMMHC-IIA directly contributes to the pathogenesis of SFTSV and may be a useful target for antiviral interventions against the viral infection.

  12. Relating double field theory to the scalar potential of N=2 gauged supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Blumenhagen, Ralph [Max-Planck-Institut für Physik (Werner-Heisenberg-Institut), Föhringer Ring 6, München, 80805 (Germany); Font, Anamaria [Max-Planck-Institut für Physik (Werner-Heisenberg-Institut), Föhringer Ring 6, München, 80805 (Germany); Arnold Sommerfeld Center for Theoretical Physics, LMU,Theresienstr. 37, München, 80333 (Germany); Plauschinn, Erik [Arnold Sommerfeld Center for Theoretical Physics, LMU,Theresienstr. 37, München, 80333 (Germany)

    2015-12-18

    The double field theory action in the flux formulation is dimensionally reduced on a Calabi-Yau three-fold equipped with non-vanishing type IIB geometric and non-geometric fluxes. First, we rewrite the metric-dependent reduced DFT action in terms of quantities that can be evaluated without explicitly knowing the metric on the Calabi-Yau manifold. Second, using properties of special geometry we obtain the scalar potential of N=2 gauged supergravity. After an orientifold projection, this potential is consistent with the scalar potential arising from the flux-induced superpotential, plus an additional D-term contribution.

  13. Down-Regulation of the Na+-Coupled Phosphate Transporter NaPi-IIa by AMP-Activated Protein Kinase

    Directory of Open Access Journals (Sweden)

    Miribane Dërmaku-Sopjani

    2013-11-01

    Full Text Available Background/Aims: The Na+-coupled phosphate transporter NaPi-IIa is the main carrier accomplishing renal tubular phosphate reabsorption. It is driven by the electrochemical Na+ gradient across the apical cell membrane, which is maintained by Na+ extrusion across the basolateral cell membrane through the Na+/K+ ATPase. The operation of NaPi-IIa thus requires energy in order to avoid cellular Na+ accumulation and K+ loss with eventual decrease of cell membrane potential, Cl- entry and cell swelling. Upon energy depletion, early inhibition of Na+-coupled transport processes may delay cell swelling and thus foster cell survival. Energy depletion is sensed by the AMP-activated protein kinase (AMPK, a serine/threonine kinase stimulating several cellular mechanisms increasing energy production and limiting energy utilization. The present study explored whether AMPK influences the activity of NAPi-IIa. Methods: cRNA encoding NAPi-IIa was injected into Xenopus oocytes with or without additional expression of wild-type AMPK (AMPKα1-HA+AMPKβ1-Flag+AMPKγ1-HA, of inactive AMPKαK45R (AMPKα1K45R+AMPKβ1-Flag+AMPKγ1-HA or of constitutively active AMPKγR70Q (AMPKα1-HA+AMPKβ1-Flag+AMPKγ1R70Q. NaPi-IIa activity was estimated from phosphate-induced current in dual electrode voltage clamp experiments. Results: In NaPi-IIa-expressing, but not in water-injected Xenopus oocytes, the addition of phosphate (1 mM to the extracellular bath solution generated a current (Ip, which was significantly decreased by coexpression of wild-type AMPK and of AMPKγR70Q but not of AMPKαK45R. The phosphate-induced current in NaPi-IIa- and AMPK-expressing Xenopus ooocytes was significantly increased by AMPK inhibitor Compound C (20 µM. Kinetic analysis revealed that AMPK significantly decreased the maximal transport rate. Conclusion: The AMP-activated protein kinase AMPK is a powerful regulator of NaPi-IIa and thus of renal tubular phosphate transport.

  14. On moduli spaces in AdS{sub 4} supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Alwis, Senarath de [Colorado Univ., Boulder, CO (United States). Dept. of Physics; Louis, Jan [Hamburg Univ. (Germany). Fachbereich 12 - Physik; Hamburg Univ. (Germany). Zentrum fuer Mathematische Physik; McAllister, Liam [Cornell Univ., Ithaca, NY (United States). Dept. of Physics; Triendl, Hagen [CERN, Geneva (Switzerland). Theory Division, Physics Dept.; Westphal, Alexander [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany). Gruppe Theorie

    2013-12-15

    We study the structure of the supersymmetric moduli spaces of N=1 and N=2 supergravity theories in AdS{sub 4} backgrounds. In the N=1 case, the moduli space cannot be a complex submanifold of the Kaehler field space, but is instead real with respect to the inherited complex structure. In N=2 supergravity the same result holds for the vector multiplet moduli space, while the hypermultiplet moduli space is a Kaehler submanifold of the quaternionic-Kaehler field space. These findings are in agreement with AdS/CFT considerations.

  15. Differential and integral forms in supergauge theories and supergravity

    International Nuclear Information System (INIS)

    Zupnik, B.M.; Pak, D.G.

    1989-01-01

    D = 3, 4, N = 1 supergauge theories and D = 3, N = 1 supergravity are considered in the superfield formalism by using differential and integral forms. A special map of the space of differential forms into the space of integral forms is proposed. By means of this map we find the superfield Chern-Simons terms in D = 3, N = 1 Yang-Mills theory and supergravity. The integral forms corresponding to superfield invariants of D = 4, N = 1 supergauge theory have also been constructed. (Author)

  16. Supersymmetric couplings and trajectories in N = 1 supergravity

    International Nuclear Information System (INIS)

    Castagnino, M.; Umerez, N.; Domenech, G.; Levinas, M.

    1989-01-01

    The present work deals with the classical behaviour of matter represented by chiral multiplets in a background of N = 1 supergravity. The WKB method is used. It is shown that supersymmetric coupling leads, at the lowest order, to a non-geodesic motion law for spin-1/2 matter. This result permits us to establish physical differences with respect to gravitational theories with minimal coupled matter Lagrangians. Deviations from the Newton law are found, allowing us to speculate about low-energy effects for testing supergravity. (author)

  17. General dimensional reduction of ten-dimensional supergravity and superstring

    International Nuclear Information System (INIS)

    Ferrara, S.; Porrati, M.

    1986-01-01

    Dimensional reductions of supergravity theories are shown to yield to specific glasses of four-dimensional no-scale models with N=4, 2 or 1 residual supersymmetry. N=1 ''maximal'' supergravity lagrangian, corresponding to the ''untwisted'' sector of orbifold compactification of superstrings, contains nine families and has a no-scale structure based on the Kaehler manifold [SU(3, 3+3n)/SU(3)xSU(3+3n)]x[SU(1, 1)/U(1)]. The quantum consistency of the resulting theories give information on the non Kaluza-Klein (string) ''twisted'' sector. (orig.)

  18. Representations of algebras of extended supersymmetry and linearised supergravity theories

    International Nuclear Information System (INIS)

    Tejlor, Dzh.

    1985-01-01

    In the lecture an attempt is made to acquaint the reader with the theory of extended supersymmetry, to characterize the corresponding particle spectrum and to explain how it can be used in supersymmetry with the least difficulties. Superalgebras are classified, their irreducible representations are given. Superfields and superspace are introduced, their role in the superalgebra realization is analyzed. Examples of linearized Lagrangians and auxiliary fields for the theories of supergravity with N=1 and N=2 are presented. Methods of spin reduction with the central charges are considered. The possibility to construct supergravity model with N>=3 off mass shell is considered

  19. 6D supergravity. Warped solution and gravity mediated supersymmetry breaking

    Energy Technology Data Exchange (ETDEWEB)

    Luedeling, C

    2006-07-15

    We consider compactified six-dimensional gauged supergravity and find the general warped solution with four-dimensional maximal symmetry. Important features of the solution such as the number and position of singularities are determined by a free holomorphic function. Furthermore, in a particular torus compactification we derive the supergravity coupling of brane fields by the Noether procedure and investigate gravity-mediated supersymmetry breaking. The effective Kaehler potential is not sequestered, yet tree level gravity mediation is absent as long as the superpotential is independent of the radius modulus. (orig.)

  20. 6D supergravity. Warped solution and gravity mediated supersymmetry breaking

    International Nuclear Information System (INIS)

    Luedeling, C.

    2006-07-01

    We consider compactified six-dimensional gauged supergravity and find the general warped solution with four-dimensional maximal symmetry. Important features of the solution such as the number and position of singularities are determined by a free holomorphic function. Furthermore, in a particular torus compactification we derive the supergravity coupling of brane fields by the Noether procedure and investigate gravity-mediated supersymmetry breaking. The effective Kaehler potential is not sequestered, yet tree level gravity mediation is absent as long as the superpotential is independent of the radius modulus. (orig.)

  1. d=3 Chern-Simons action, supergravity and quantization

    International Nuclear Information System (INIS)

    Dayi, O.F.

    1989-01-01

    An interpretation of three-dimensional simple supergravity as a pure Chern-Simons gauge action is shown to be valid up to the one loop level. Canonical quantization of this system does not lead to an explicit definition of the physical Hilbert space. Hence another formulation of the N = 1 three-dimensional supergravity is introduced. In this formalism an explicit definition of the physical Hilbert space is possible, but still one has to solve the problems of showing that there exists a global set of coordinates and of defining the inner product. (author). 10 refs

  2. Extremal Black Holes in Supergravity and the Bekenstein-Hawking Entropy

    Directory of Open Access Journals (Sweden)

    R. D'Auria

    2002-03-01

    Full Text Available Abstract: We review some results on the connection among supergravity central charges, BPS states and Bekenstein-Hawking entropy. In particular, N = 2 super-gravity in four dimensions is studied in detail. For higher N supergravities we just give an account of the general theory specializing the discussion to the N = 8 case when one half of supersymmetry is preserved. We stress the fact that for extremal supergravity black holes the entropy formula is topological, that is the entropy turns out to be a moduli independent quantity and can be written in terms of invariants of the duality group of the supergravity theory.

  3. Surgery or radiation therapy for Stage I and IIA carcinoma of the cervix

    International Nuclear Information System (INIS)

    Brady, L.W.

    1979-01-01

    The choice of treatment in carcinoma of the cervix is best decided after careful individual appraisal has been carried out. For best results, a long-term view must be agreed upon initially and careful followup by the same team is obligatory. At present, surgery, radiation therapy, and a combination of these two modalities have been employed successfully to manage carcinoma of the cervix. To a great extent, the facilities, the experience, and the interest of the personnel involved influence the type of therapy that will be employed. Generally speaking, the choice of treatment is determined primarily by the stage of the disease process. Radical surgery in the management of patients with Stage I and Stage II-A carcinoma of the cervix must be planned to include within the en bloc dissection the uterus, tubes, ovaries, and regional lymph node drainage from those organs. Therefore, a radical lymphadnectomy is an integral and important part of the overall management program when radical surgery is performed. In most institutions, radiation therapy is used most frequently to treat carcinoma of the cervix in Stages I and II-A. The data from various institutions indicate significant survival potential from radiation therapy treatment programs that are appropriately devised. In Stages I and II-A the complications are minimal in character (primarily proctitis and cystitis); generally, they involve a potential incidence of about six percent

  4. Potential Therapeutic Roles of Tanshinone IIA in Human Bladder Cancer Cells

    Directory of Open Access Journals (Sweden)

    Sheng-Chun Chiu

    2014-09-01

    Full Text Available Tanshinone IIA (Tan-IIA, one of the major lipophilic components isolated from the root of Salviae Miltiorrhizae, has been found to exhibit anticancer activity in various cancer cells. We have demonstrated that Tan-IIA induces apoptosis in several human cancer cells through caspase- and mitochondria-dependent pathways. Here we explored the anticancer effect of Tan-IIA in human bladder cancer cell lines. Our results showed that Tan-IIA caused bladder cancer cell death in a time- and dose-dependent manner. Tan-IIA induced apoptosis through the mitochondria-dependent pathway in these bladder cancer cells. Tan-IIA also suppressed the migration of bladder cancer cells as revealed by the wound healing and transwell assays. Finally, combination therapy of Tan-IIA with a lower dose of cisplatin successfully killed bladder cancer cells, suggesting that Tan-IIA can serve as a potential anti-cancer agent in bladder cancer.

  5. Quantum field theories coupled to supergravity. AdS/CFT and local couplings

    International Nuclear Information System (INIS)

    Grosse, J.

    2006-01-01

    This dissertation is devoted to the investigation of the interplay of supersymmetric Yang-Mills theories (SYM) and supergravity (SUGRA). The topic is studied from two points of view: Firstly from the point of view of AdS/CFT correspondence, which realises the coupling of four dimensional superconformal N=4 SYM theory and ten dimensional type IIB SUGRA in a holographic way. In order to arrive at theories that resemble quantum chromodynamics (QCD) more closely, fundamental fields are introduced using probe D7-branes and nontrivial background configuration are considered. In particular supergravity solutions that are only asymptotically anti-de Sitter and break supersymmetry are used. This allows the description of spontaneous chiral symmetry breaking. The meson spectrum is calculated and the existence of an associated Goldstone mode is demonstrated. Moreover it is shown that highly radially excited mesons are not degenerate. Additionally instanton configurations on the D7-branes are investigated, which lead to a holographic description of the dual field theory's Higgs branch. Finally a holographic description of heavy-light mesons is developed, which are mesons consisting of quarks with a large mass difference, such that a treatment of B mesons can be achieved. The second approach to the topic of this thesis is the technique of socalled space-time dependent couplings (also known as ''local couplings''), where coupling constants are promoted to external sources. This allows to explore the conformal anomaly of quantum field theories coupled to a classical gravity background. The technique is extended to the superfield description of N=1 supergravity, a complete basis for the anomaly is given and the consistency conditions that arise from a cohomological treatment are calculated. Possible implications for an extension of Zamolodchikov's c-theorem to four dimensional supersymmetric quantum field theories are discussed. (orig.)

  6. Quantum field theories coupled to supergravity. AdS/CFT and local couplings

    Energy Technology Data Exchange (ETDEWEB)

    Grosse, J.

    2006-08-03

    This dissertation is devoted to the investigation of the interplay of supersymmetric Yang-Mills theories (SYM) and supergravity (SUGRA). The topic is studied from two points of view: Firstly from the point of view of AdS/CFT correspondence, which realises the coupling of four dimensional superconformal N=4 SYM theory and ten dimensional type IIB SUGRA in a holographic way. In order to arrive at theories that resemble quantum chromodynamics (QCD) more closely, fundamental fields are introduced using probe D7-branes and nontrivial background configuration are considered. In particular supergravity solutions that are only asymptotically anti-de Sitter and break supersymmetry are used. This allows the description of spontaneous chiral symmetry breaking. The meson spectrum is calculated and the existence of an associated Goldstone mode is demonstrated. Moreover it is shown that highly radially excited mesons are not degenerate. Additionally instanton configurations on the D7-branes are investigated, which lead to a holographic description of the dual field theory's Higgs branch. Finally a holographic description of heavy-light mesons is developed, which are mesons consisting of quarks with a large mass difference, such that a treatment of B mesons can be achieved. The second approach to the topic of this thesis is the technique of socalled space-time dependent couplings (also known as ''local couplings''), where coupling constants are promoted to external sources. This allows to explore the conformal anomaly of quantum field theories coupled to a classical gravity background. The technique is extended to the superfield description of N=1 supergravity, a complete basis for the anomaly is given and the consistency conditions that arise from a cohomological treatment are calculated. Possible implications for an extension of Zamolodchikov's c-theorem to four dimensional supersymmetric quantum field theories are discussed. (orig.)

  7. Spontaneous breaking of supersymmetry and gauge invariance in supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Sohnius, M. (European Organization for Nuclear Research, Geneva (Switzerland)); West, P. (King' s Coll., London (UK). Dept. of Mathematics)

    1982-08-09

    Using the new minimal auxillary fields of N = 1 supergravity it is found possible to construct a model of local supersymmetry which spontaneously breaks both supersymmetry and gauge invariance. The status of the cosmological constant resulting from this breaking is discussed.

  8. Spontaneous breaking of supersymmetry and gauge invariance in supergravity

    International Nuclear Information System (INIS)

    Sohnius, M.; West, P.

    1982-01-01

    Using the new minimal auxillary fields of N = 1 supergravity it is found possible to construct a model of local supersymmetry which spontaneously breaks both supersymmetry and gauge invariance. The status of the cosmological constant resulting from this breaking is discussed. (orig.)

  9. Grassmann expansion of the classical N=2 supergravity field equations

    International Nuclear Information System (INIS)

    Embacher, F.

    1984-01-01

    The classical field equations of N=2 supergravity are expanded with respect to an infinite dimensional Grassmann algebra. The general freedom in constructing classical solution is exhibited. As an application, a uniqueness theorem for supersymmetric extreme black holes is given. (Author)

  10. Supersymmetric black holes in N = 2 supergravity theory

    International Nuclear Information System (INIS)

    Aichelburg, P.C.

    1982-01-01

    We present an exact, asymptotically flat, stationary solution of the field equations of O(2) extended supergravity theory. This solution has a mass, central electric charge as well as a supercharge and constitutes the first exact, supersymmetric generalization of the black hole geometries. The solution generalizes the extreme Reissner-Nordstroem black holes. (Author)

  11. Half-supersymmetric solutions in five-dimensional supergravity

    International Nuclear Information System (INIS)

    Gutowski, Jan B.; Sabra, Wafic

    2007-01-01

    We present a systematic classification of half-supersymmetric solutions of gauged N = 2, D = 5 supergravity coupled to an arbitrary number of abelian vector multiplets for which at least one of the Killing spinors generate a time-like Killing vector

  12. General supersymmetric solutions of five-dimensional supergravity

    International Nuclear Information System (INIS)

    Gutowski, Jan B.; Sabra, Wafic

    2005-01-01

    The classification of 1/4-supersymmetric solutions of five dimensional gauged supergravity coupled to arbitrary many abelian vector multiplets, which was initiated elsewhere, is completed. The structure of all solutions for which the Killing vector constructed from the Killing spinor is null is investigated in both the gauged and the ungauged theories and some new solutions are constructed

  13. Helical Phase Inflation and Monodromy in Supergravity Theory

    Directory of Open Access Journals (Sweden)

    Tianjun Li

    2015-01-01

    Full Text Available We study helical phase inflation which realizes “monodromy inflation” in supergravity theory. In the model, inflation is driven by the phase component of a complex field whose potential possesses helicoid structure. We construct phase monodromy based on explicitly breaking global U(1 symmetry in the superpotential. By integrating out heavy fields, the phase monodromy from single complex scalar field is realized and the model fulfills natural inflation. The phase-axion alignment is achieved from explicitly symmetry breaking and gives super-Planckian phase decay constant. The F-term scalar potential provides strong field stabilization for all the scalars except inflaton, which is protected by the approximate global U(1 symmetry. Besides, we show that helical phase inflation can be naturally realized in no-scale supergravity with SU(2,1/SU(2×U(1 symmetry since the supergravity setup needed for phase monodromy is automatically provided in the no-scale Kähler potential. We also demonstrate that helical phase inflation can be reduced to another well-known supergravity inflation model with shift symmetry. Helical phase inflation is free from the UV-sensitivity problem although there is super-Planckian field excursion, and it suggests that inflation can be effectively studied based on supersymmetric field theory while a UV-completed framework is not prerequisite.

  14. Well-posedness of (N = 1) classical supergravity

    International Nuclear Information System (INIS)

    Bao, D.; Choquet-Bruhat, Y.; Isenberg, J.; Yasskin, P.B.

    1985-01-01

    In this paper we investigate whether classical (N = 1) supergravity has a well-posed locally causal Cauchy problem. We define well-posedness to mean that any choice of initial data (from an appropriate function space) which satisfies the supergravity constraint equations and a set of gauge conditions can be continuously developed into a space-time solution of the supergravity field equations around the initial surface. Local causality means that the domains of dependence of the evolution equations coincide with those determined by the light cones. We show that when the fields of classical supergravity are treated as formal objects, the field equations are (under certain gauge conditions) equivalent to a coupled system of quasilinear nondiagonal second-order partial differential equations which is formally nonstrictly hyperbolic (in the sense of Leray--Ohya). Hence, if the fields were numerical valued, there would be an applicable existence theorem leading to well-posedness. We shall observe that well-posedness is assured if the fields are taken to be Grassmann (i.e., exterior algebra) valued, for then the second-order system decouples into the vacuum Einstein equation and a sequence of numerical valued linear diagonal strictly hyperbolic partial differential equations which can be solved successively

  15. Chaotic inflation in supergravity after Planck and BICEP2

    International Nuclear Information System (INIS)

    Kallosh, Renata; Linde, Andrei

    2014-05-01

    We discuss the general structure and observational consequences of some of the simplest versions of chaotic inflation in supergravity in relation to the data by Planck 2013 and BICEP2. We show that minimal modifications to the simplest quadratic potential are sufficient to provide a controllable tensor mode signal and a suppression of CMB power at large angular scales.

  16. N=2 supergravity in superspace: the invariant action

    International Nuclear Information System (INIS)

    Gal'perin, A.S.; Sokachev, E.

    1987-01-01

    This paper continues the formulation of harmonic superspace supergravity. We write down the invariant action for the first off-shell version of the theory. The proof of the invariance relies on the existence of a new 'hybrid' basis in harmonic superspace in which semi-chirality combined with analyticity are manifest

  17. Gauge fixing of Chern-Simons N-extended supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Ney, W G [Centro Brasileiro de Pesquisas Fisicas (CBPF), Rio de Janeiro, RJ (Brazil); Centro Federal de Educacao Tecnologica (CEFET), Campos dos Goytacazes, RJ (Brazil); Piguet, O [Universidade Federal do Espirito Santo (UFES), ES 29000-001, Vitoria (Brazil); Spalenza, W [Centro Brasileiro de Pesquisas Fisicas (CBPF), Rio de Janeiro, RJ (Brazil)

    2004-08-01

    We treat N-extended supergravity in 2+1 space-time dimensions as a Yang-Mills gauge field with Chern-Simons action associated to the N-extended Poincare supergroup. We fix the gauge of this theory within the Batalin-Vilkovisky scheme. (orig.)

  18. Gauge fixing of Chern-Simons N-extended supergravity

    International Nuclear Information System (INIS)

    Ney, W.G.; Piguet, O.; Spalenza, W.

    2004-01-01

    We treat N-extended supergravity in 2+1 space-time dimensions as a Yang-Mills gauge field with Chern-Simons action associated to the N-extended Poincare supergroup. We fix the gauge of this theory within the Batalin-Vilkovisky scheme. (orig.)

  19. The superspace-translation tensor and linearized N = 1 supergravities

    International Nuclear Information System (INIS)

    Bedding, S.P.; Lang, W.

    1982-01-01

    The recently proposed superspace-translation tensor is considered as the source of supergravities in the context of N = 1 supersymmetry. It is shown how the structure of this tensor leads to a complete evaluation of the linearized supervielbein in terms of unconstrained prepotentials with derived transformation laws. Connection with formulations using torsion constraints is made. (orig.)

  20. Hidden symmetries in minimal five-dimensional supergravity

    International Nuclear Information System (INIS)

    Poessel, Markus; Silva, Sebastian

    2004-01-01

    We study the hidden symmetries arising in the dimensional reduction of d=5, N=2 supergravity to three dimensions. Extending previous partial results for the bosonic part, we give a derivation that includes fermionic terms, shedding light on the appearance of the local hidden symmetry SO(4) in the reduction

  1. (2, 0) tensor multiplets and conformal supergravity in D = 6

    NARCIS (Netherlands)

    Bergshoeff, Eric; Sezgin, Ergin; Proeyen, Antoine Van

    1999-01-01

    We construct the supercurrent multiplet that contains the energy–momentum tensor of the (2, 0) tensor multiplet. By coupling this multiplet of currents to the fields of conformal supergravity, we first construct the linearized superconformal transformations rules of the (2, 0) Weyl multiplet.

  2. Which compactifications of D=11 supergravity are stable

    International Nuclear Information System (INIS)

    Page, D.N.; Pope, C.N.

    1984-01-01

    We complete the stability analysis of all known Freund-Rubin solutions of eleven-dimensional supergravity by determining the necessary and sufficient conditions for Qsup(pqr) spaces (U(1) bundles over S 2 xS 2 xS 2 ) to be stable. (orig.)

  3. Classifying supersymmetric solutions in 3D maximal supergravity

    Science.gov (United States)

    de Boer, Jan; Mayerson, Daniel R.; Shigemori, Masaki

    2014-12-01

    String theory contains various extended objects. Among those, objects of codimension two (such as the D7-brane) are particularly interesting. Codimension-two objects carry non-Abelian charges which are elements of a discrete U-duality group and they may not admit a simple spacetime description, in which case they are known as exotic branes. A complete classification of consistent codimension-two objects in string theory is missing, even if we demand that they preserve some supersymmetry. As a step toward such a classification, we study the supersymmetric solutions of 3D maximal supergravity, which can be regarded as an approximate description of the geometry near codimension-two objects. We present a complete classification of the types of supersymmetric solutions that exist in this theory. We found that this problem reduces to that of classifying nilpotent orbits associated with the U-duality group, for which various mathematical results are known. We show that the only allowed supersymmetric configurations are 1/2, 1/4, 1/8, and 1/16 BPS, and determine the nilpotent orbits that they correspond to. One example of 1/16 BPS configurations is a generalization of the MSW system, where momentum runs along the intersection of seven M5-branes. On the other hand, it turns out exceedingly difficult to translate this classification into a simple criterion for supersymmetry in terms of the non-Abelian (monodromy) charges of the objects. For example, it can happen that a supersymmetric solution exists locally but cannot be extended all the way to the location of the object. To illustrate the various issues that arise in constructing supersymmetric solutions, we present a number of explicit examples.

  4. Position of nonmuscle myosin heavy chain IIA (NMMHC-IIA) mutations predicts the natural history of MYH9-related disease

    DEFF Research Database (Denmark)

    Pecci, A.; Panza, E.; Pujol-Moix, N.

    2008-01-01

    MYH9-related disease (MYH9-RD) is a rare autosomal-dominant disorder caused by mutations in MYH9, the gene for the heavy chain of nonmuscle myosin IIA (NMMHC-IIA). All patients present from birth with macrothrombocytopenia, but in infancy or adult life, some of them develop sensorineural deafness...... to 50 unrelated pedigrees. The risk of noncongenital manifestations associated with different genotypes was estimated over time by event-free survival analysis. We demonstrated that all subjects with mutations in the motor domain of NMMHC-IIA present with severe thrombocytopenia and develop nephritis...... and deafness before the age of 40 years, while those with mutations in the tail domain have a much lower risk of noncongenital complications and significantly higher platelet counts. We also evaluated the clinical course of patients with mutations in the four most frequently affected residues of NMMHC...

  5. Type IIA2 urethral duplication: report of an unusual case

    African Journals Online (AJOL)

    obstruction and recurrent urinary tract infection due to a stenosed dorsal urethra .... the child complained of nocturnal incontinence, but this diminished gradually .... urethra because it is hypoplastic and the risk for inadequate urine flow is high.

  6. Type IIA2 urethral duplication: report of an unusual case

    African Journals Online (AJOL)

    ultrasonography (US) showed left-sided hydroureterone- phrosis with a distended thick-walled bladder. US showed the right testis to be enlarged with increased vascularity suggestive of epididymo-orchitis. A retrograde urethro- gram showed a sagittal duplication of urethra, with the narrow dorsal urethra originating from the ...

  7. On a supersymmetric completion of the R4 term in IIB supergravity

    International Nuclear Information System (INIS)

    Haro, Sebastian de; Sinkovics, Annamaria; Skenderis, Kostas

    2003-01-01

    We analyze the possibility of constructing a supersymmetric invariant that contains the R 4 term among its components as a superpotential term in type IIB on-shell superspace. We consider a scalar superpotential, i.e. an arbitrary holomorphic function of a chiral scalar superfield. In general, type IIB superspace does not allow for the existence of chiral superfields, but the obstruction vanishes for a specific superfield, the dilaton superfield. This superfield contains all fields of type IIB supergravity among its components, and its existence is implied by the solution of the Bianchi identities. The construction requires the existence of an appropriate chiral measure, and we find an obstruction to the existence of such a measure. The obstruction is closely related to the obstruction for the existence of chiral superfields and is non-linear in the fields. These results imply that the type IIB superinvariant related to the R 4 term is not associated with a scalar chiral superpotential

  8. Black holes and groups of type 7

    Indian Academy of Sciences (India)

    Supergravity; groups of type 7; black holes; quantum field theory. ... representation are reviewed, along with a connection between special Kähler geometry and a 'generalization' of groups of type 7. ... Pramana – Journal of Physics | News.

  9. Japanese contributions to IAEA INTOR workshop, phase IIA

    International Nuclear Information System (INIS)

    Fujisawa, Noboru; Sugihara, Masayoshi; Shimada, Michiya; Saito, Seiji.

    1982-11-01

    This report corresponds to Chapter VI of Japanese contribution report to IAEA INTOR workshop, Phase IIA. Special emphasis is placed on pumped limiter analysis for comparative studies between limiter and divertor concepts. Pumping characteristics of divertor/limiter and radiation cooling of diverted plasmas by impurities are also intensively studied. (author)

  10. Japanese contributions to IAEA INTOR workshop, phase IIA

    International Nuclear Information System (INIS)

    Miyamoto, Kenro; Sugihara, Masayoshi; Kimura, Haruyuki

    1982-11-01

    This report corresponds to Chapter V of Japanese contribution report to IAEA INTOR workshop, Phase IIA. Physics studies for radio frequency heating are concentrated on heating to ignition by means of ion cyclotron and lower hybrid ranges of frequencies, and discharge start-up assist and current drive by lower hybrid range. Their system design studies are also performed. (author)

  11. Japanese contributions to IAEA INTOR workshop, phase IIA

    International Nuclear Information System (INIS)

    Tone, Tatsuzo; Shiraishi, Kensuke; Watanabe, Hitoshi

    1982-11-01

    This report describes the engineering testing to be carried out in INTOR, which has been presented for discussions of Group C in the Phase IIA of the INTOR Workshop. Structural material testing, blanket testing and long-term operation are covered. A design of test modules to be installed in the INTOR is proposed. (author)

  12. Class IIa histone deacetylases are conserved regulators of circadian function.

    Science.gov (United States)

    Fogg, Paul C M; O'Neill, John S; Dobrzycki, Tomasz; Calvert, Shaun; Lord, Emma C; McIntosh, Rebecca L L; Elliott, Christopher J H; Sweeney, Sean T; Hastings, Michael H; Chawla, Sangeeta

    2014-12-05

    Class IIa histone deacetylases (HDACs) regulate the activity of many transcription factors to influence liver gluconeogenesis and the development of specialized cells, including muscle, neurons, and lymphocytes. Here, we describe a conserved role for class IIa HDACs in sustaining robust circadian behavioral rhythms in Drosophila and cellular rhythms in mammalian cells. In mouse fibroblasts, overexpression of HDAC5 severely disrupts transcriptional rhythms of core clock genes. HDAC5 overexpression decreases BMAL1 acetylation on Lys-537 and pharmacological inhibition of class IIa HDACs increases BMAL1 acetylation. Furthermore, we observe cyclical nucleocytoplasmic shuttling of HDAC5 in mouse fibroblasts that is characteristically circadian. Mutation of the Drosophila homolog HDAC4 impairs locomotor activity rhythms of flies and decreases period mRNA levels. RNAi-mediated knockdown of HDAC4 in Drosophila clock cells also dampens circadian function. Given that the localization of class IIa HDACs is signal-regulated and influenced by Ca(2+) and cAMP signals, our findings offer a mechanism by which extracellular stimuli that generate these signals can feed into the molecular clock machinery. © 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

  13. Single-centered black hole microstate degeneracies from instantons in supergravity

    Science.gov (United States)

    Murthy, Sameer; Reys, Valentin

    2016-04-01

    We obtain holographic constraints on the microscopic degeneracies of black holes by computing the exact macroscopic quantum entropy using localization, including the effects of string worldsheet instantons in the supergravity effective action. For 1/4 -BPS black holes in type II string theory on K3 × T 2, the constraints can be explicitly checked against expressions for the microscopic BPS counting functions that are known in terms of certain mock modular forms. We find that the effect of including the infinite sum over instantons in the holomorphic prepotential of the supergravity leads to a sum over Bessel functions with successively sub-leading arguments as in the Rademacher expansion of Jacobi forms — but begins to disagree with such a structure near an order where the mock modular nature becomes relevant. This leads to a systematic method to recover the polar terms of the microscopic degeneracies from the degeneracy of instantons (the Gromov-Witten invariants). We check explicitly that our formula agrees with the known microscopic answer for the first seven values of the magnetic charge invariant.

  14. Single-centered black hole microstate degeneracies from instantons in supergravity

    International Nuclear Information System (INIS)

    Murthy, Sameer; Reys, Valentin

    2016-01-01

    We obtain holographic constraints on the microscopic degeneracies of black holes by computing the exact macroscopic quantum entropy using localization, including the effects of string worldsheet instantons in the supergravity effective action. For (1/4)-BPS black holes in type II string theory on K3×T 2 , the constraints can be explicitly checked against expressions for the microscopic BPS counting functions that are known in terms of certain mock modular forms. We find that the effect of including the infinite sum over instantons in the holomorphic prepotential of the supergravity leads to a sum over Bessel functions with successively sub-leading arguments as in the Rademacher expansion of Jacobi forms — but begins to disagree with such a structure near an order where the mock modular nature becomes relevant. This leads to a systematic method to recover the polar terms of the microscopic degeneracies from the degeneracy of instantons (the Gromov-Witten invariants). We check explicitly that our formula agrees with the known microscopic answer for the first seven values of the magnetic charge invariant.

  15. Minimal $R+R^2$ Supergravity Models of Inflation Coupled to Matter

    CERN Document Server

    Ferrara, S

    2014-01-01

    The supersymmetric extension of "Starobinsky" $R+\\alpha R^2$ models of inflation is particularly simple in the "new minimal" formalism of supergravity, where the inflaton has no scalar superpartners. This paper is devoted to matter couplings in such supergravity models. We show how in the new minimal formalism matter coupling presents certain features absent in other formalisms. In particular, for the large class of matter couplings considered in this paper, matter must possess an R-symmetry, which is gauged by the vector field which becomes dynamical in the "new minimal" completion of the $R+\\alpha R^2$ theory. Thus, in the dual formulation of the theory, where the gauge vector is part of a massive vector multiplet, the inflaton is the superpartner of the massive vector of a nonlinearly realized R-symmetry. The F-term potential of this theory is of no-scale type, while the inflaton potential is given by the D-term of the gauged R-symmetry. The absolute minimum of the potential is always exactly supersymmetri...

  16. Modified Dynamical Supergravity Breaking and Off-Diagonal Super-Higgs Effects

    CERN Document Server

    Gheorghiu, Tamara; Vacaru, Sergiu

    2015-01-01

    We argue that generic off-diagonal vacuum and nonvacuum solutions for Einstein manifolds mimic physical effects in modified gravity theories (MGTs) and encode certain models of $f(R,T,...)$, Ho\\vrava type with dynamical Lorentz symmetry breaking, induced effective mass for graviton etc. Our main goal is to investigate the dynamical breaking of local supersymmetry determined by off--diagonal solutions in MGTs encoded as effective Einstein spaces. This includes the Deser-Zumino super--Higgs effect, for instance, for an one--loop potential in a (simple but representative) model of $\\mathcal{N}=1, D=4$ supergravity. We develop and apply a new geometric techniques which allows us to decouple the gravitational field equations and integrate them in very general forms with metrics and vierbein fields depending on all spacetime coordinates via various generating and integration functions and parameters. We study how solutions in MGTs may be related to dynamical generation of a gravitino mass and supergravity breaking.

  17. Chaotic inflation in no-scale supergravity with string inspired moduli stabilization

    International Nuclear Information System (INIS)

    Li, Tianjun; Li, Zhijin; Nanopoulos, Dimitri V.

    2015-01-01

    The simple chaotic inflation is highly consistent with the BICEP2 experiment, and no-scale supergravity can be realized naturally in various string compactifications. Thus, we construct a chaotic inflation model in no-scale supergravity inspired from Type IIB string compactification with an anomalous U(1) X gauged symmetry. We introduce two moduli T 1 and T 2 which transform non-trivially under U(1) X , and some pairs of fundamental quarks charged under the SU(N) x U(1) X gauge group. The non-trivial transformations of moduli under U(1) X lead to a moduli-dependent Fayet-Iliopoulos (FI) term. The modulus T 2 and the real component of T 1 are stabilized by the non-perturbative effect from quark condensation and the U(1) X D-term. In particular, the stabilization from the anomalous U(1) X D-term with moduli-dependent FI term is crucial for inflation since it gives heavy mass to the real component of the modulus T 1 while keeping its axionic part light. Choosing the proper parameters, we obtain a global Minkowski vacuum where the imaginary part of T 1 has a quadratic potential for chaotic inflation. (orig.)

  18. The secretory phospholipase A2 group IIA: a missing link between inflammation, activated renin-angiotensin system, and atherogenesis?

    Directory of Open Access Journals (Sweden)

    Dimitar Divchev

    2008-06-01

    Full Text Available Dimitar Divchev, Bernhard SchiefferDepartment of Cardiology and Angiology, Medizinische Hochschule Hannover, GermanyAbstract: Inflammation, lipid peroxidation and chronic activation of the renin–angiotensin system (RAS are hallmarks of the development of atherosclerosis. Recent studies have suggested the involvement of the pro-inflammatory secretory phospholipase A2 (sPLA2-IIA in atherogenesis. This enzyme is produced by different cell types through stimulation by proinflammatory cytokines. It is detectable in the intima and in media smooth muscle cells, not only in atherosclerotic lesions but also in the very early stages of atherogenesis. sPLA2-IIA can hydrolyse the phospholipid monolayers of low density lipoproteins (LDL. Such modified LDL show increased affinity to proteoglycans. The modified particles have a greater tendency to aggregate and an enhanced ability to insert cholesterol into cells. This modification may promote macrophage LDL uptake leading to the formation of foam cells. Furthermore, sPLA2-IIA is not only a mediator for localized inflammation but may be also used as an independent predictor of adverse outcomes in patients with stable coronary artery disease or acute coronary syndromes. An interaction between activated RAS and phospholipases has been indicated by observations showing that inhibitors of sPLA2 decrease angiotensin (Ang II-induced macrophage lipid peroxidation. Meanwhile, various interactions between Ang II and oxLDL have been demonstrated suggesting a central role of sPLA2-IIA in these processes and offering a possible target for treatment. The role of sPLA2-IIA in the perpetuation of atherosclerosis appears to be the missing link between inflammation, activated RAS and lipidperoxidation.Keywords: secretory phospholipase A2, lipoproteins, renin-angiotensin system, inflammation, atherosclerosis

  19. Genetic organization of ascB-dapE internalin cluster serves as a potential marker for Listeria monocytogenes sublineages IIA, IIB, and IIC.

    Science.gov (United States)

    Chen, Jianshun; Fang, Chun; Zhu, Ningyu; Lv, Yonghui; Cheng, Changyong; Bei, Yijiang; Zheng, Tianlun; Fang, Weihuan

    2012-05-01

    Listeria monocytogenes is an important foodborne pathogen that comprises four genetic lineages: I, II, III, and IV. Of these, lineage II is frequently recovered from foods and environments and responsible for the increasing incidence of human listeriosis. In this study, the phylogenetic structure of lineage II was determined through sequencing analysis of the ascB-dapE internalin cluster. Fifteen sequence types proposed by multilocus sequence typing based on nine housekeeping genes were grouped into three distinct sublineages, IIA, IIB, and IIC. Organization of the ascBdapE internalin cluster could serve as a molecular marker for these sublineages, with inlGHE, inlGC2DE, and inlC2DE for IIA, IIB, and IIC, respectively. These sublineages displayed specific genetic and phenotypic characteristics. IIA and IIC showed a higher frequency of recombination (rho/theta). However, recombination events had greater effect (r/m) on IIB, leading to its high nucleotide diversity. Moreover, IIA and IIB harbored a wider range of internalin and stress-response genes, and possessed higher nisin tolerance, whereas IIC contained the largest portion of low-virulent strains owing to premature stop codons in inlA. The results of this study indicate that IIA, IIB, and IIC might occupy different ecological niches, and IIB might have a better adaptation to a broad range of environmental niches.

  20. Non-linear realizations and higher curvature supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Farakos, F. [Dipartimento di Fisica e Astronomia ' ' Galileo Galilei' ' , Universita di Padova (Italy); INFN, Sezione di Padova (Italy); Ferrara, S. [Department of Theoretical Physics, Geneva (Switzerland); INFN - Laboratori Nazionali di Frascati, Frascati (Italy); Department of Physics and Astronomy, Mani L. Bhaumik Institute for Theoretical Physics, U.C.L.A., Los Angeles, CA (United States); Kehagias, A. [Physics Division, National Technical University of Athens (Greece); Luest, D. [Arnold Sommerfeld Center for Theoretical Physics, Muenchen (Germany); Max-Planck-Institut fuer Physik, Muenchen (Germany)

    2017-12-15

    We focus on non-linear realizations of local supersymmetry as obtained by using constrained superfields in supergravity. New constraints, beyond those of rigid supersymmetry, are obtained whenever curvature multiplets are affected as well as higher derivative interactions are introduced. In particular, a new constraint, which removes a very massive gravitino is introduced, and in the rigid limit it merely reduces to an explicit supersymmetry breaking. Higher curvature supergravities free of ghosts and instabilities are also obtained in this way. Finally, we consider direct coupling of the goldstino multiplet to the super Gauss-Bonnet multiplet and discuss the emergence of a new scalar degree of freedom. (copyright 2017 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  1. Supersymmetric warped AdS in extended topologically massive supergravity

    International Nuclear Information System (INIS)

    Deger, N.S.; Kaya, A.; Samtleben, H.; Sezgin, E.

    2014-01-01

    We determine the most general form of off-shell N=(1,1) supergravity field configurations in three dimensions by requiring that at least one off-shell Killing spinor exists. We then impose the field equations of the topologically massive off-shell supergravity and find a class of solutions whose properties crucially depend on the norm of the auxiliary vector field. These are spacelike-squashed and timelike-stretched AdS 3 for the spacelike and timelike norms, respectively. At the transition point where the norm vanishes, the solution is null warped AdS 3 . This occurs when the coefficient of the Lorentz–Chern–Simons term is related to the AdS radius by μℓ=2. We find that the spacelike-squashed AdS 3 can be modded out by a suitable discrete subgroup of the isometry group, yielding an extremal black hole solution which avoids closed timelike curves

  2. Supersymmetric solutions of N =(1 ,1 ) general massive supergravity

    Science.gov (United States)

    Deger, N. S.; Nazari, Z.; Sarıoǧlu, Ö.

    2018-05-01

    We construct supersymmetric solutions of three-dimensional N =(1 ,1 ) general massive supergravity (GMG). Solutions with a null Killing vector are, in general, pp-waves. We identify those that appear at critical points of the model, some of which do not exist in N =(1 ,1 ) new massive supergravity (NMG). In the timelike case, we find that many solutions are common with NMG, but there is a new class that is genuine to GMG, two members of which are stationary Lifshitz and timelike squashed AdS spacetimes. We also show that in addition to the fully supersymmetric AdS vacuum, there is a second AdS background with a nonzero vector field that preserves 1 /4 supersymmetry.

  3. Gauge and matter fields coupled to N=2 supergravity

    International Nuclear Information System (INIS)

    Wit, B. de; Lauwers, P.G.; Philippe, R.; Su, S.-Q.; Proeyen, A. van.

    1983-07-01

    The authors consider the potential of a general matter system of N=2 vector and scalar multiplets coupled to supergravity. For lagrangians that are initially quadratic in the matter fields the potential is proved to be either positive or unbounded from below. The results have been obtained in the framework of a superconformal multiplet calculus, and it has been verified that they can be derived from each of the three off-shell representations. As an example the authors consider SO(6) Yang-Mills theory coupled to scalar multiplets in the 10+10 representation, which, for suitably chosen parameters, leads to the potential of gauged N=8 supergravity. Finally, a discussion of the possibility to set residual nonabelian symmetry groups after breaking of N=8 supersymmetry to N=1 or 2 is presented. (Auth.)

  4. Generalized curvature and the equations of D=11 supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Bandos, Igor A. [Departamento de Fisica Teorica, Universidad de Valencia and IFIC (CSIC-UVEG), 46100-Burjassot (Valencia) (Spain); Institute for Theoretical Physics, NSC ' Kharkov Institute of Physics and Technology' , UA-61108 Kharkov (Ukraine); Azcarraga, Jose A. de [Departamento de Fisica Teorica, Universidad de Valencia and IFIC (CSIC-UVEG), 46100-Burjassot (Valencia) (Spain)]. E-mail: j.a.de.azcarraga@ific.uv.es; Picon, Moises [Departamento de Fisica Teorica, Universidad de Valencia and IFIC (CSIC-UVEG), 46100-Burjassot (Valencia) (Spain); Department of Physics and Astronomy, University of Southern California, Los Angeles, CA 90089-2535 (United States); Varela, Oscar [Departamento de Fisica Teorica, Universidad de Valencia and IFIC (CSIC-UVEG), 46100-Burjassot (Valencia) (Spain); Michigan Center for Theoretical Physics, Randall Laboratory, Department of Physics, University of Michigan, Ann Arbor, MI 48109-1120 (United States)

    2005-05-26

    It is known that, for zero fermionic sector, {psi}{sub {mu}}{sup {alpha}}(x)=0, the bosonic equations of Cremmer-Julia-Scherk eleven-dimensional supergravity can be collected in a compact expression, Rab{alpha}{gamma}{gamma}b{gamma}{beta}=0, which is a condition on the curvature R{alpha}{beta} of the generalized connection w. In this Letter we show that the equation Rbc{alpha}{gamma}{gamma}abc{gamma}{beta}=4i((D-bar {psi}){sub bc}{gamma}{sup [abc{sub {beta}({psi}{sub d}{gamma}{sup d}]){sub {alpha}}), where D-bar is the covariant derivative for the generalized connection w, collects all the bosonic equations of D=11 supergravity when the gravitino is nonvanishing, {psi}{sub {mu}}{sup {alpha}}(x)<>0.

  5. One-loop divergences in the quantum theory of supergravity

    International Nuclear Information System (INIS)

    Nieuwenhuizen, P. van; Vermaseren, J.A.M.

    1976-01-01

    Supergravity does not lead to a finite quantum theory of gravitation when coupled to the spin 1, 1/2 matter multiplet. The S-matrix of photon-photon scattering diverges; its divergences are proportional to the square of the photon energy-momentum tensor, in agreement with electro-magnetic duality and chiral invariance. The graviton self-energy corrections are divergent in pure supergravity as well as in the coupled Maxwell-Einstein system and satisfy their Ward identity because the supersymmetry ghost field is commuting. The photon-graviton vertex corrections diverge, as expected from the non-invariance of the action under local scale transformations, and satisfy the equivalence principle at the quantum level. The photon self-energy is divergent. (Auth.)

  6. Some features of SUSY breaking in N=2 supergravity

    International Nuclear Information System (INIS)

    Cecotti, S.; Giradello, L.; Porrati, M.

    1984-08-01

    We discuss some features of SUSY breaking in N=2 Supergravity. Firstly, we show that in a general N=2 Sugra model (constructed according to the tensor calculus) all stationary points of the potential, at Λ=0, are fully supersymmetric if the compensating multiplet is not gauged. Thus a viable super-Higgs effect in N=2 supergravity can occur only in the presence of a Fayet-Iliopoulos term. Then we present an explicit model with two scales of breaking in anti-de Sitter space. Moreover, the ratio of the two gravitino masses is sliding i.e. not determined by the classical potential. In the extreme situation one of the gravitino mass equals √-Λ/3, and thus we have partial super-Higgs (in AdS space). The cosmological constant may be arranged to an arbitrary small value while keeping the mass of the heavy gravitino constant. (author)

  7. Gauge theory of gravity and supergravity on a group manifold

    International Nuclear Information System (INIS)

    Ne'eman, Y.; Regge, T.

    1977-12-01

    The natural arena for the physics of gravity, supergravity and their enlargements appears to be the group manifold of the Poincare group P, the graded Poincare group GP of supersymmetry, and the corresponding enlargements. The dynamics of these theories correspond to geometrical algorithms in P and GP. Differential geometry on Lie groups is reviewed and results applied to P and GP. Curvature, gauge transformations and factorization are introduced. Also reviewed is the general coordinate transformation group and a hybrid gauge transformation, the anholonomized G.C.T. gauge. A study is made of the construction of an action, including the introduction of a set of special 2 forms, the ''pseudo curvatures.'' The possibilities of factorization in supersymmetry are analyzed. The version of supergravity is present which has now become a completely geometrical theory

  8. On eleven-dimensional supergravity and Chern-Simons theory

    Energy Technology Data Exchange (ETDEWEB)

    Izaurieta, Fernando, E-mail: fizaurie@ucsc.cl [Departamento de Matematica y Fisica Aplicadas, Universidad Catolica de la Santisima Concepcion, Alonso de Ribera 2850, 4090541 Concepcion (Chile); Instituto de Matematicas, Universidad Nacional Autonoma de Mexico, Av. Insurgentes Sur s/n, D.F. (Mexico); Departament de Fisica Teorica, Universitat de Valencia, C/ Dr. Moliner 50, 46100 Burjassot, Valencia (Spain); Rodriguez, Eduardo, E-mail: edurodriguez@ucsc.cl [Departamento de Matematica y Fisica Aplicadas, Universidad Catolica de la Santisima Concepcion, Alonso de Ribera 2850, 4090541 Concepcion (Chile)

    2012-02-11

    We probe in some depth into the structure of eleven-dimensional, osp(32|1)-based Chern-Simons supergravity, as put forward by Troncoso and Zanelli (TZ) in 1997. We find that the TZ Lagrangian may be cast as a polynomial in 1/l, where l is a length, and compute explicitly the first three dominant terms. The term proportional to 1/l{sup 9} turns out to be essentially the Lagrangian of the standard 1978 supergravity theory of Cremmer, Julia and Scherk, thus establishing a previously unknown relation between the two theories. The computation is nontrivial because, when written in a sufficiently explicit way, the TZ Lagrangian has roughly one thousand non-explicitly Lorentz-covariant terms. Specially designed algebraic techniques are used to accomplish the results.

  9. Axion-dilaton domain walls and fake supergravity

    International Nuclear Information System (INIS)

    Sonner, Julian; Townsend, Paul K

    2007-01-01

    Dynamical systems methods are used to investigate domain-wall solutions of a two-parameter family of models in which gravity is coupled to an axion and to a dilaton with an exponential potential of either sign. A complete global analysis is presented for (i) constant axion and (ii) flat walls, including a study of bifurcations and a new exact domain-wall solution with non-constant axion. We reconsider 'fake-supergravity' issues in light of these results. We show, by example, how domain walls determine multi-valued superpotentials that branch at stationary points that are not stationary points of the potential, and we apply this result to potentials with anti-de Sitter vacua. We also show by example that 'adapted' truncation to a single-scalar model may be inconsistent, and we propose a 'generalized' fake-supergravity formalism that applies in some such cases

  10. Complete D =11 embedding of SO(8) supergravity

    Science.gov (United States)

    Varela, Oscar

    2018-02-01

    The truncation formulas of D =11 supergravity on S7 to D =4 N =8 SO(8)-gauged supergravity are completed to include the full nonlinear dependence of the D =11 three-form potential A^ (3 ) on the D =4 fields, and their consistency is shown. The full embedding into A^ (3 ) is naturally expressed in terms of a restricted version, still N =8 but only SL(8)-covariant, of the D =4 tensor hierarchy. The redundancies introduced by this approach are removed at the level of the field strength F^ (4 ) by exploiting D =4 duality relations. Finally, new expressions for the full consistent truncation formulas are given that are explicit in all D =11 and D =4 fields.

  11. Brane inflation: A field theory approach in background supergravity

    International Nuclear Information System (INIS)

    Choudhury, Sayantan; Pal, Supratik

    2012-01-01

    We propose a model of inflation in the framework of brane cosmology driven by background supergravity. Starting from bulk supergravity we construct the inflaton potential on the brane and employ it to investigate for the consequences to inflationary paradigm. To this end, we derive the expressions for the important parameters in brane inflation, which are somewhat different from their counterparts in standard cosmology, using the one loop radiative corrected potential. We further estimate the observable parameters and find them to fit well with recent observational data. We have studied extensively reheating phenomenology, which explains the thermal history of the universe and leptogenesis through the production of thermal gravitino pertaining to the particle physics phenomenology of the early universe.

  12. Low-energy supergravities from heterotic compactification on reduced structure backgrounds

    International Nuclear Information System (INIS)

    Martinez Pedrera, Danny Manuel

    2009-10-01

    In this thesis, the compactification of heterotic supergravity on six-dimensional manifolds with SU(2) and SU(3) structure is studied. For the SU(2)-structure backgrounds, the spectrum and the bosonic action of the effective theory in four dimensions are obtained. The results are gauged versions of the ungauged N=2 supergravity obtained after compactification on K3 x T 2 . The gauge algebra and the Killing prepotentials are also computed. For the SU(3)-structure backgrounds, the couplings of the resulting N=1 supergravity are computed by reducing terms on the heterotic supergravity action involving fermionic fields, and are further checked by computing the supersymmetry variations of the fermions. (orig.)

  13. Supersymmetric Yang-Mills theory on conformal supergravity backgrounds in ten dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Medeiros, Paul de; Figueroa-O’Farrill, José [Maxwell Institute and School of Mathematics, The University of Edinburgh,James Clerk Maxwell Building, Peter Guthrie Tait Road, Edinburgh EH9 3FD (United Kingdom)

    2016-03-14

    We consider bosonic supersymmetric backgrounds of ten-dimensional conformal supergravity. Up to local conformal isometry, we classify the maximally supersymmetric backgrounds, determine their conformal symmetry superalgebras and show how they arise as near-horizon geometries of certain half-BPS backgrounds or as a plane-wave limit thereof. We then show how to define Yang-Mills theory with rigid supersymmetry on any supersymmetric conformal supergravity background and, in particular, on the maximally supersymmetric backgrounds. We conclude by commenting on a striking resemblance between the supersymmetric backgrounds of ten-dimensional conformal supergravity and those of eleven-dimensional Poincaré supergravity.

  14. Supergravity duals of supersymmetric four dimensional gauge theories

    Energy Technology Data Exchange (ETDEWEB)

    Bigazzi, F [Abdus Salam International Centre for Theoretical Physics, Trieste (Italy); Cotrone, A L [Centre de Physique Theorique, Ecole Polytechnique, Palaiseau Cedex (France); [INFN, Rome (Italy); Petrini, M [Centre de Physique Theorique, Ecole Polytechnique, Palaiseau (France); Zaffaroni, A [Universita di Milano-Bicocca and INFN, Milan (Italy)

    2002-03-01

    This article contains an overview of some recent attempts of understanding supergravity and string duals of four dimensional gauge theories using the AdS/CFT correspondence. We discuss the general philosophy underlying the various ways to realize Super Yang-Mills theories in terms of systems of branes. We then review some of the existing duals for N=2 and N=1 theories. We also discuss differences and similarities with realistic theories. (author)

  15. The potentials of the gauged N=8 supergravity theories

    International Nuclear Information System (INIS)

    Hull, C.M.

    1985-01-01

    The potentials of the SO(p,q) gaugings of N=8 supergravity are investigated for critical points. The SO(7,1) gauging has no G 2 -invariant critical points, the SO(6,2) theory has no SU(3) invariant critical points and the SO(5,3) gauging has only one SO(5)-invariant critical point, with positive cosmological constant, SO(5) x SO(3) symmetry and no supersymmetry. (orig.)

  16. Null half-supersymmetric solutions in five-dimensional supergravity

    International Nuclear Information System (INIS)

    Grover, Jai; Gutowski, Jan B.; Sabra, Wafic

    2008-01-01

    We classify half-supersymmetric solutions of gauged N = 2, D = 5 supergravity coupled to an arbitrary number of abelian vector multiplets for which all of the Killing spinors generate null Killing vectors. We show that there are four classes of solutions, and in each class we find the metric, scalars and gauge field strengths. When the scalar manifold is symmetric, the solutions correspond to a class of local near horizon geometries recently found by Kunduri and Lucietti.

  17. O' R inflation in F-term supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Zheng, Sibo, E-mail: sibozheng.zju@gmail.com

    2017-06-15

    The supersymmetric realization of inflation in F-term supergravity is usually plagued by the well known “η” problem. In this paper, a broad class of small-field examples is realized by employing general O' Raifeartaigh superpotentials, where the moduli is identified as the massless inflaton. For illustration we present the simplest example in detail, which can be considered as a generalization of hybrid inflation.

  18. Minimal scalar-less matter-coupled supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Dall' Agata, Gianguido, E-mail: dallagat@pd.infn.it [Dipartimento di Fisica e Astronomia “Galileo Galilei”, Università di Padova, Via Marzolo 8, I-35131 Padova (Italy); INFN, Sezione di Padova, Via Marzolo 8, I-35131 Padova (Italy); Centre de Physique Théorique, École Polytechnique, CNRS, Université Paris-Saclay, F-91128 Palaiseau (France); Ferrara, Sergio [Theory Unit, Physics Department, CERN, CH-1211 Geneva 23 (Switzerland); INFN, Laboratori Nazionali di Frascati, Via Enrico Fermi 40, I-00044 Frascati (Italy); Department of Physics and Astronomy, UCLA, Los Angeles, CA 90095-1547 (United States); Zwirner, Fabio [Dipartimento di Fisica e Astronomia “Galileo Galilei”, Università di Padova, Via Marzolo 8, I-35131 Padova (Italy); INFN, Sezione di Padova, Via Marzolo 8, I-35131 Padova (Italy); Theory Unit, Physics Department, CERN, CH-1211 Geneva 23 (Switzerland)

    2016-01-10

    We build the minimal supergravity model where the nilpotent chiral goldstino superfield is coupled to a chiral matter superfield, realising a different non-linear representation through a mixed nilpotency constraint. The model describes the spontaneous breaking of local supersymmetry in the presence of a generically massive Majorana fermion, but in the absence of elementary scalars. The sign and the size of the cosmological constant, the spectrum and the four-fermion interactions are controlled by suitable parameters.

  19. Top-down approach to unified supergravity models

    International Nuclear Information System (INIS)

    Hempfling, R.

    1994-03-01

    We introduce a new approach for studying unified supergravity models. In this approach all the parameters of the grand unified theory (GUT) are fixed by imposing the corresponding number of low energy observables. This determines the remaining particle spectrum whose dependence on the low energy observables can now be investigated. We also include some SUSY threshold corrections that have previously been neglected. In particular the SUSY threshold corrections to the fermion masses can have a significant impact on the Yukawa coupling unification. (orig.)

  20. Unlocking the axion-dilaton in 5D supergravity

    Czech Academy of Sciences Publication Activity Database

    Raeymaekers, Joris; Van den Bleeken, D.

    2014-01-01

    Roč. 11, Nov (2014), s. 1-54 ISSN 1029-8479 R&D Projects: GA ČR(CZ) GA14-31689S Institutional support: RVO:68378271 Keywords : supergravity models * d-branes * m-theory * black holes in string theory Subject RIV: BE - Theoretical Physics Impact factor: 6.111, year: 2014 http://link.springer.com/article/10.1007%2FJHEP11%282014%29029

  1. Minimal scalar-less matter-coupled supergravity

    CERN Document Server

    Dall'Agata, Gianguido; Zwirner, Fabio

    2016-01-01

    We build the minimal supergravity model where the nilpotent chiral goldstino superfield is coupled to a chiral matter superfield, realising a different non-linear representation through a mixed nilpotency constraint. The model describes the spontaneous breaking of local supersymmetry in the presence of a generically massive Majorana fermion, but in the absence of elementary scalars. The sign and the size of the cosmological constant, the spectrum and the four-fermion interactions are controlled by suitable parameters.

  2. Supergravity, Dark Energy and the Fate of the Universe

    Energy Technology Data Exchange (ETDEWEB)

    Shmakova, Marina

    2002-09-27

    We propose a description of dark energy and acceleration of the universe in extended supergravities with de Sitter (dS) solutions. Some of them are related to M-theory with non-compact internal spaces. Masses of ultra-light scalars in these models are quantized in units of the Hubble constant: m{sup 2} = nH{sup 2}. If dS solution corresponds to a minimum of the effective potential, the universe eventually becomes dS space. If dS solution corresponds to a maximum or a saddle point, which is the case in all known models based on N = 8 supergravity, the flat universe eventually stops accelerating and collapses to a singularity. We show that in these models, as well as in the simplest models of dark energy based on N = 1 supergravity, the typical time remaining before the global collapse is comparable to the present age of the universe, t = O(10{sup 10}) years. We discuss the possibility of distinguishing between various models and finding our destiny using cosmological observations.

  3. Group manifold approach to gravity and supergravity theories

    International Nuclear Information System (INIS)

    d'Auria, R.; Fre, P.; Regge, T.

    1981-05-01

    Gravity theories are presented from the point of view of group manifold formulation. The differential geometry of groups and supergroups is discussed first; the notion of connection and related Yang-Mills potentials is introduced. Then ordinary Einstein gravity is discussed in the Cartan formulation. This discussion provides a first example which will then be generalized to more complicated theories, in particular supergravity. The distinction between ''pure'' and ''impure' theories is also set forth. Next, the authors develop an axiomatic approach to rheonomic theories related to the concept of Chevalley cohomology on group manifolds, and apply these principles to N = 1 supergravity. Then the panorama of so far constructed pure and impure group manifold supergravities is presented. The pure d = 5 N = 2 case is discussed in some detail, and N = 2 and N = 3 in d = 4 are considered as examples of the impure theories. The way a pure theory becomes impure after dimensional reduction is illustrated. Next, the role of kinematical superspace constraints as a subset of the group-manifold equations of motion is discussed, and the use of this approach to obtain the auxiliary fields is demonstrated. Finally, the application of the group manifold method to supersymmetric Super Yang-Mills theories is addressed

  4. Extremal black hole/CFT correspondence in (gauged) supergravities

    International Nuclear Information System (INIS)

    Chow, David D. K.; Cvetic, M.; Lue, H.; Pope, C. N.

    2009-01-01

    We extend the investigation of the recently proposed Kerr/conformal field theory correspondence to large classes of rotating black hole solutions in gauged and ungauged supergravities. The correspondence, proposed originally for four-dimensional Kerr black holes, asserts that the quantum states in the near-horizon region of an extremal rotating black hole are holographically dual to a two-dimensional chiral theory whose Virasoro algebra arises as an asymptotic symmetry of the near-horizon geometry. In fact, in dimension D there are [(D-1)/2] commuting Virasoro algebras. We consider a general canonical class of near-horizon geometries in arbitrary dimension D, and show that in any such metric the [(D-1)/2] central charges each imply, via the Cardy formula, a microscopic entropy that agrees with the Bekenstein-Hawking entropy of the associated extremal black hole. In the remainder of the paper we show for most of the known rotating black hole solutions of gauged supergravity, and for the ungauged supergravity solutions with four charges in D=4 and three charges in D=5, that their extremal near-horizon geometries indeed lie within the canonical form. This establishes that, in all these examples, the microscopic entropies of the dual conformal field theories agree with the Bekenstein-Hawking entropies of the extremal rotating black holes.

  5. On the effective theory of type II string compactifications on nilmanifolds and coset spaces

    International Nuclear Information System (INIS)

    Caviezel, Claudio

    2009-01-01

    In this thesis we analyzed a large number of type IIA strict SU(3)-structure compactifications with fluxes and O6/D6-sources, as well as type IIB static SU(2)-structure compactifications with fluxes and O5/O7-sources. Restricting to structures and fluxes that are constant in the basis of left-invariant one-forms, these models are tractable enough to allow for an explicit derivation of the four-dimensional low-energy effective theory. The six-dimensional compact manifolds we studied in this thesis are nilmanifolds based on nilpotent Lie-algebras, and, on the other hand, coset spaces based on semisimple and U(1)-groups, which admit a left-invariant strict SU(3)- or static SU(2)-structure. In particular, from the set of 34 distinct nilmanifolds we identified two nilmanifolds, the torus and the Iwasawa manifold, that allow for an AdS 4 , N = 1 type IIA strict SU(3)-structure solution and one nilmanifold allowing for an AdS 4 , N = 1 type IIB static SU(2)-structure solution. From the set of all the possible six-dimensional coset spaces, we identified seven coset spaces suitable for strict SU(3)-structure compactifications, four of which also allow for a static SU(2)-structure compactification. For all these models, we calculated the four-dimensional low-energy effective theory using N = 1 supergravity techniques. In order to write down the most general four-dimensional effective action, we also studied how to classify the different disconnected ''bubbles'' in moduli space. (orig.)

  6. Characteristic of Lamb Sausages Fermented by Indonesian Meat-Derived Probiotic, Lactobacillus plantarum IIA-2C12 and Lactobacillus acidophilus IIA-2B4

    Directory of Open Access Journals (Sweden)

    Noraimah Binti Sulaiman

    2016-08-01

    Full Text Available Probiotic is a group of microorganism, mainly from lactic acid bacteria (LAB, widely used to increase functionality of various foodstuffs, including lamb which was limited by its goaty odor and short life issue. This study aimed to evaluate the characteristic of lamb sausages fermented by either Lactobacillus plantarum IIA-2C12 or L. acidophilus IIA-2B4 isolated from local cattle in Indonesia, and stored for 21 days at low temperature (4oC. Fermented lamb sausages were made with the addition of L. plantarum IIA-2C12 and L. acidophilus IIA-2B4 with three replications. The result showed that pH value, protein, and cholesterol contents of the sausages with addition of L. acidophilus IIA-2B4 were higher (P<0.05 than that of L. plantarum IIA-2C12. Meanwhile, the sausage fermented with L. plantarum IIA-2C12 had higher titratable acid (TA value, texture, and the content of fat, carbohydrate, tyrosine, lysine, myristoleic (C14:1, pentadecanoic (C15:0, heneicosanoic (C21:0 and cis-11-eicosatrienoic (C20:1 as compared to that of  L. acidophilus 2C12-2B4. Final population of LAB in the sausage fermented by L. plantarum IIA-2C12 was also higher than that of L. acidophilus IIA-2B4, yet both can be categorized as a probiotic. The differences between characteristics of the physicochemical traits and microbiological quality of the sausage fermentation associated with the addition of L. plantarum IIA-2C12 or L. acidophilus IIA-2B4. The 21 days of storage at cold temperatures with probiotics addition could extend shelf life and maintain quality of fermented sausage.

  7. Development of Class IIa Bacteriocins as Therapeutic Agents

    Directory of Open Access Journals (Sweden)

    Christopher T. Lohans

    2012-01-01

    Full Text Available Class IIa bacteriocins have been primarily explored as natural food preservatives, but there is much interest in exploring the application of these peptides as therapeutic antimicrobial agents. Bacteriocins of this class possess antimicrobial activity against several important human pathogens. Therefore, the therapeutic development of these bacteriocins will be reviewed. Biological and chemical modifications to both stabilize and increase the potency of bacteriocins are discussed, as well as the optimization of their production and purification. The suitability of bacteriocins as pharmaceuticals is explored through determinations of cytotoxicity, effects on the natural microbiota, and in vivo efficacy in mouse models. Recent results suggest that class IIa bacteriocins show promise as a class of therapeutic agents.

  8. Development of Class IIa Bacteriocins as Therapeutic Agents

    OpenAIRE

    Christopher T. Lohans; John C. Vederas

    2012-01-01

    Class IIa bacteriocins have been primarily explored as natural food preservatives, but there is much interest in exploring the application of these peptides as therapeutic antimicrobial agents. Bacteriocins of this class possess antimicrobial activity against several important human pathogens. Therefore, the therapeutic development of these bacteriocins will be reviewed. Biological and chemical modifications to both stabilize and increase the potency of bacteriocins are discussed, as well as ...

  9. The tensor calculus and matter coupling of the alternative minimal auxiliary field formulation of N = 1 supergravity

    International Nuclear Information System (INIS)

    Sohnius, M.; West, P.

    1982-01-01

    The tensor calculus for the new alternative minimal auxiliary field formulation of N = 1 supergravity is given. It is used to construct the couplings of this formulation of supergravity to matter. These couplings are found to be different, in several respects to those of the old minimal formulation of N = 1 supergravity. (orig.)

  10. Charged Fermions Tunneling from a Rotating Charged Black Hole in 5-Dimensional Gauged Supergravity

    International Nuclear Information System (INIS)

    Li Huiling; Lin Rong; Wang Chuanyin

    2010-01-01

    Recent research shows that Hawking radiation from black hole horizon can be treated as a quantum tunneling process, and fermions tunneling method can successfully recover Hawking temperature. In this tunneling framework, choosing a set of appropriate matrices γ μ is an important technique for fermions tunneling method. In this paper, motivated by Kerner and Man's fermions tunneling method of 4 dimension black holes, we further improve the analysis to investigate Hawking tunneling radiation from a rotating charged black hole in 5-dimensional gauged supergravity by constructing a set of appropriate matrices γ μ for general covariant Dirac equation. Finally, the expected Hawking temperature of the black hole is correctly recovered, which takes the same form as that obtained by other methods. This method is universal, and can also be directly extend to the other different-type 5-dimensional charged black holes.

  11. Starobinsky-like inflation and running vacuum in the context of Supergravity

    CERN Document Server

    Basilakos, Spyros; Solà, Joan

    2016-01-01

    We describe the primeval inflationary phase of the early Universe within a quantum field theoretical (QFT) framework that can be viewed as the effective action of vacuum decay in the early times. Interestingly enough, the model accounts for the "graceful exit" of the inflationary phase into the standard radiation regime. The underlying QFT framework considered here is Supergravity (SUGRA), more specifically an existing formulation in which the Starobinsky-type inflation (de-Sitter background) emerges from the quantum corrections to the effective action after integrating out the gravitino fields in their (dynamically induced) massive phase. We also demonstrate that the structure of the effective action in this model is consistent with the generic idea of renormalization group (RG) running of the cosmological parameters, specifically it follows from the corresponding RG equation for the vacuum energy density as a function of the Hubble rate, $\\rho_{\\Lambda}(H)$. Overall our combined approach amounts to a concre...

  12. Is spontaneous breaking of R-parity feasible in minimal low-energy supergravity

    International Nuclear Information System (INIS)

    Gato, B.; Leon, J.; Perez-Mercader, J.; Quiros, M.

    1985-01-01

    Spontaneous violation of lepton number without breaking Lorentz invariance can, in principle, be incorporated in models with softly broken supersymmetry. We study the situation for minimal low-energy supergravity models coming from a GUT (hence not having hierarchy destabilizing light singlets) and where the SU(2)xU(1) breaking is radiative. It is found that for this type of model, R-parity breaking requires either too heavy a top quark for a realistic superpartner spectrum or too light a superpartner spectrum for a realistic top quark, making the spontaneous violation of lepton number in the third generation incompatible with present experimental data. We do not discard the possibility of having it in a fourth, heavier, generation. (orig.)

  13. Non-perturbative approach to 2D-supergravity and super-Virasoro constraints

    CERN Document Server

    Becker, M

    1994-01-01

    The coupling of N=1 SCFT of type (4m,2) to two-dimensional supergravity can be formulated non-perturbatively in terms of a discrete super-eigenvalue model proposed by Alvarez-Gaum\\'e, et al. We derive the superloop equations that describe, in the double scaling limit, the non-perturbative solution of this model. These equations are equivalent to the double scaled super-Virasoro constraints satisfied by the partition function. They are formulated in terms of a \\widehat c=1 theory, with a \\IZ_2-twisted scalar field and a Weyl-Majorana fermion in the Ramond sector. We have solved the superloop equations to all orders in the genus expansion and obtained the explicit expressions for the correlation functions of gravitationally dressed scaling operators in the NS- and R-sector. In the double scaling limit, we obtain a formulation of the model in terms of a new supersymmetric extension of the KdV hierarchy.

  14. Dimensional reduction in field theory and hidden symmetries in extended supergravity

    International Nuclear Information System (INIS)

    Kremmer, E.

    1985-01-01

    Dimensional reduction in field theories is discussed both in theories which do not include gravity and in gravity theories. In particular, 11-dimensional supergravity and its reduction to 4 dimensions is considered. Hidden symmetries of supergravity with N=8 in 4 dimensions, global E 7 and local SU(8)-invariances in particular are detected. The hidden symmmetries permit to interpret geometrically the scalar fields

  15. Generalized Lie superalgebras and a supergravity with a positive cosmological constant

    International Nuclear Information System (INIS)

    Vasil'ev, M.A.

    1984-01-01

    A new law for forming the Hermitian conjugation makes it possible to construct a Hermitian action for a supergravity with a positive cosmological constant Λ. This modified conjugation leads to generalized (Z 2 x Z 2 -gauge) Lie superalgebras that correspond to a supergravity with Λ>0

  16. Off-shell supergravity in five dimensions and supersymmetric brane world scenarios

    International Nuclear Information System (INIS)

    Zucker, M.

    2000-08-01

    In order to supersymmetrize the Randall-Sundrum setup it proves useful to start with an off-shell formulation of five dimensional supergravity. So far, this theory has only been known on-shell. The first part of this thesis is concerned with the construction of five dimensional N=2 off-shell supergravity. We develop the complete local tensor calculus. The basic building block is the minimal multiplet which contains the propagating fields of supergravity. The minimal multiplet is completed by several auxiliary fields, extending the field content to (40+40) components. The supersymmetry transformation laws for all matter multiplets with (8 + 8) components are given. Using these results, action formulas for all multiplets are presented. In particular, we give three different off-shell formulations of supergravity and gauged supergravity. Next, gauged supergravity on the orbifold S 1 /Z 2 is constructed. Consistent implementation of the Z 2 transformation shows that the minimal multiplet projected to the fixpoints of the orbifold forms a non-minimal N=1 supergravity multiplet in four dimensions. We use this observation to supersymmetrize the Randall-Sundrum scenario. This result is extended to matter located at the fixpoints which we couple in a manifestly supersymmetric way to the supergravity in the bulk. We consider chiral and super Yang-Mills multiplets at the fixpoints. (orig.)

  17. Effects of the gravivector and graviscalar fields in N = 2,8 supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Bellucci, S. [INFN, Laboratori Nazionali di Frascati, Rome (Italy); Faraoni, V. [Victoria Univ., BC (Canada). Dept. of Physics and Astronomy

    1996-05-01

    The available tests of the equivalence principle constrain the mass of the Higgs-like boson appearing in extended supergravity theories. The authors determine the constraints imposed by high precision experiments on the antigravity fields (gravivector and graviscalar) arising from N = 2,8 supergravity.

  18. Hamiltonian formalism, quantization and S matrix for supergravity. [S matrix, canonical constraints

    Energy Technology Data Exchange (ETDEWEB)

    Fradkin, E S; Vasiliev, M A [AN SSSR, Moscow. Fizicheskij Inst.

    1977-12-05

    The canonical formalism for supergravity is constructed. The algebra of canonical constraints is found. The correct expression for the S matrix is obtained. Usual 'covariant methods' lead to an incorrect S matrix in supergravity since a new four-particle interaction of ghostfields survives in the Lagrangian expression of the S matrix.

  19. Solution of N=2 supergravity constraints in terms of N=1 superfields

    Energy Technology Data Exchange (ETDEWEB)

    Awada, M.A.; Mokhtari, S. (Imperial Coll. of Science and Technology, London (UK). Blackett Lab.)

    1984-08-30

    The constraints of N=2 supergravity are given in terms of N=1 supergravity and matter fields. We exhibit the solution of these constraints to all orders in terms of N=1 superfields; and we propose a structure for the action.

  20. The solution of N=2 supergravity constraints in terms of N=1 superfields

    International Nuclear Information System (INIS)

    Awada, M.A.; Mokhtari, S.

    1984-01-01

    The constraints of N=2 supergravity are given in terms of N=1 supergravity and matter fields. We exhibit the solution of these constraints to all orders in terms of N=1 superfields; and we propose a structure for the action. (orig.)

  1. Off-diagonal deformations of Kerr metrics and black ellipsoids in heterotic supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Vacaru, Sergiu I. [Quantum Gravity Research, Topanga, CA (United States); University ' ' Al. I. Cuza' ' , Project IDEI, Iasi (Romania); Irwin, Klee [Quantum Gravity Research, Topanga, CA (United States)

    2017-01-15

    Geometric methods for constructing exact solutions of equations of motion with first order α{sup '} corrections to the heterotic supergravity action implying a nontrivial Yang-Mills sector and six-dimensional, 6-d, almost-Kaehler internal spaces are studied. In 10-d spacetimes, general parametrizations for generic off-diagonal metrics, nonlinear and linear connections, and matter sources, when the equations of motion decouple in very general forms are considered. This allows us to construct a variety of exact solutions when the coefficients of fundamental geometric/physical objects depend on all higher-dimensional spacetime coordinates via corresponding classes of generating and integration functions, generalized effective sources and integration constants. Such generalized solutions are determined by generic off-diagonal metrics and nonlinear and/or linear connections; in particular, as configurations which are warped/compactified to lower dimensions and for Levi-Civita connections. The corresponding metrics can have (non-) Killing and/or Lie algebra symmetries and/or describe (1+2)-d and/or (1+3)-d domain wall configurations, with possible warping nearly almost-Kaehler manifolds, with gravitational and gauge instantons for nonlinear vacuum configurations and effective polarizations of cosmological and interaction constants encoding string gravity effects. A series of examples of exact solutions describing generic off-diagonal supergravity modifications to black hole/ellipsoid and solitonic configurations are provided and analyzed. We prove that it is possible to reproduce the Kerr and other type black solutions in general relativity (with certain types of string corrections) in the 4-d case and to generalize the solutions to non-vacuum configurations in (super-) gravity/string theories. (orig.)

  2. Off-diagonal deformations of Kerr metrics and black ellipsoids in heterotic supergravity

    International Nuclear Information System (INIS)

    Vacaru, Sergiu I.; Irwin, Klee

    2017-01-01

    Geometric methods for constructing exact solutions of equations of motion with first order α ' corrections to the heterotic supergravity action implying a nontrivial Yang-Mills sector and six-dimensional, 6-d, almost-Kaehler internal spaces are studied. In 10-d spacetimes, general parametrizations for generic off-diagonal metrics, nonlinear and linear connections, and matter sources, when the equations of motion decouple in very general forms are considered. This allows us to construct a variety of exact solutions when the coefficients of fundamental geometric/physical objects depend on all higher-dimensional spacetime coordinates via corresponding classes of generating and integration functions, generalized effective sources and integration constants. Such generalized solutions are determined by generic off-diagonal metrics and nonlinear and/or linear connections; in particular, as configurations which are warped/compactified to lower dimensions and for Levi-Civita connections. The corresponding metrics can have (non-) Killing and/or Lie algebra symmetries and/or describe (1+2)-d and/or (1+3)-d domain wall configurations, with possible warping nearly almost-Kaehler manifolds, with gravitational and gauge instantons for nonlinear vacuum configurations and effective polarizations of cosmological and interaction constants encoding string gravity effects. A series of examples of exact solutions describing generic off-diagonal supergravity modifications to black hole/ellipsoid and solitonic configurations are provided and analyzed. We prove that it is possible to reproduce the Kerr and other type black solutions in general relativity (with certain types of string corrections) in the 4-d case and to generalize the solutions to non-vacuum configurations in (super-) gravity/string theories. (orig.)

  3. Inverse dualization and non-local dualities between Einstein gravity and supergravities

    International Nuclear Information System (INIS)

    Chen Chiangmei; Gal'tsov, Dmitri V; Sharakin, Sergei A

    2002-01-01

    We investigate non-local dualities between suitably compactified higher dimensional Einstein gravity and supergravities which can be revealed if one reinterprets the dualized Kaluza-Klein 2-forms in D>4 as antisymmetric forms belonging to supergravities. We find several examples of such a correspondence including one between the six-dimensional Einstein gravity and the four-dimensional Einstein-Maxwell-dilaton-axion theory (truncated N=4 supergravity), and others between the compactified eleven- and ten-dimensional supergravities and the eight- or ten-dimensional pure gravity. The Killing spinor equation of the D=11 supergravity is shown to be equivalent to the geometric Killing spinor equation in the dual gravity. We give several examples of using new dualities for solution generation and demonstrate how p-branes can be interpreted as non-local duals of pure gravity solutions. New supersymmetric solutions are presented including M2 subset of 5-brane with two rotation parameters

  4. Conformal supergravity in five dimensions: new approach and applications

    Science.gov (United States)

    Butter, Daniel; Kuzenko, Sergei M.; Novak, Joseph; Tartaglino-Mazzucchelli, Gabriele

    2015-02-01

    We develop a new off-shell formulation for five-dimensional (5D) conformal supergravity obtained by gauging the 5D superconformal algebra in superspace. An important property of the conformal superspace introduced is that it reduces to the super-conformal tensor calculus (formulated in the early 2000's) upon gauging away a number of superfluous fields. On the other hand, a different gauge fixing reduces our formulation to the SU(2) superspace of arXiv:0802.3953, which is suitable to describe the most general off-shell supergravity-matter couplings. Using the conformal superspace approach, we show how to reproduce practically all off-shell constructions derived so far, including he supersymmetric extensions of R 2 terms, thus demonstrating the power of our formulation. Furthermore, we construct for the first time a supersymmetric completion of the Ricci tensor squared term using the standard Weyl multiplet coupled to an off-shell vector multiplet. In addition, we present several procedures to generate higher-order off-shell invariants in supergravity, including higher-derivative ones. The covariant projective multiplets proposed in arXiv:0802.3953 are lifted to conformal superspace, and a manifestly superconformal action principle is given. We also introduce unconstrained prepotentials for the vector multiplet, the multiplet (i.e., the linear multiplet without central charge) and multiplets, with n = 0 , 1 , . . . Superform formulations are given for the BF action and the non-abelian Chern-Simons action. Finally, we describe locally supersymmetric theories with gauged central charge in conformal superspace.

  5. Conformal supergravity in five dimensions: new approach and applications

    Energy Technology Data Exchange (ETDEWEB)

    Butter, Daniel [Nikhef Theory Group,Science Park 105, 1098 XG Amsterdam (Netherlands); Kuzenko, Sergei M.; Novak, Joseph; Tartaglino-Mazzucchelli, Gabriele [School of Physics M013, The University of Western Australia,35 Stirling Highway, Crawley W.A. 6009 (Australia)

    2015-02-17

    We develop a new off-shell formulation for five-dimensional (5D) conformal supergravity obtained by gauging the 5D superconformal algebra in superspace. An important property of the conformal superspace introduced is that it reduces to the superconformal tensor calculus (formulated in the early 2000’s) upon gauging away a number of superfluous fields. On the other hand, a different gauge fixing reduces our formulation to the SU(2) superspace of arXiv:0802.3953, which is suitable to describe the most general off-shell supergravity-matter couplings. Using the conformal superspace approach, we show how to reproduce practically all off-shell constructions derived so far, including the supersymmetric extensions of R{sup 2} terms, thus demonstrating the power of our formulation. Furthermore, we construct for the first time a supersymmetric completion of the Ricci tensor squared term using the standard Weyl multiplet coupled to an off-shell vector multiplet. In addition, we present several procedures to generate higher-order off-shell invariants in supergravity, including higher-derivative ones. The covariant projective multiplets proposed in arXiv:0802.3953 are lifted to conformal superspace, and a manifestly superconformal action principle is given. We also introduce unconstrained prepotentials for the vector multiplet, the O(2) multiplet (i.e., the linear multiplet without central charge) and O(4+n) multiplets, with n=0,1,… Superform formulations are given for the BF action and the non-abelian Chern-Simons action. Finally, we describe locally supersymmetric theories with gauged central charge in conformal superspace.

  6. Advances in geometry and Lie algebras from supergravity

    CERN Document Server

    Frè, Pietro Giuseppe

    2018-01-01

    This book aims to provide an overview of several topics in advanced Differential Geometry and Lie Group Theory, all of them stemming from mathematical problems in supersymmetric physical theories. It presents a mathematical illustration of the main development in geometry and symmetry theory that occurred under the fertilizing influence of supersymmetry/supergravity. The contents are mainly of mathematical nature, but each topic is introduced by historical information and enriched with motivations from high energy physics, which help the reader in getting a deeper comprehension of the subject. .

  7. Supergravity, Non-Conformal Field Theories and Brane-Worlds

    CERN Document Server

    Gherghetta, Tony; Gherghetta, Tony; Oz, Yaron

    2002-01-01

    We consider the supergravity dual descriptions of non-conformal super Yang-Mills theories realized on the world-volume of Dp-branes. We use the dual description to compute stress-energy tensor and current correlators. We apply the results to the study of dilatonic brane-worlds described by non-conformal field theories coupled to gravity. We find that brane-worlds based on D4 and D5 branes exhibit a localization of gauge and gravitational fields. We calculate the corrections to the Newton and Coulomb laws in these theories.

  8. Rigid supersymmetry from conformal supergravity in five dimensions

    International Nuclear Information System (INIS)

    Pini, Alessandro; Rodriguez-Gomez, Diego; Schmude, Johannes

    2015-01-01

    We study the rigid limit of 5d conformal supergravity with minimal supersymmetry on Riemannian manifolds. The necessary and sufficient condition for the existence of a solution is the existence of a conformal Killing vector. Whenever a certain SU(2) curvature becomes abelian the backgrounds define a transversally holomorphic foliation. Subsequently we turn to the question under which circumstances these backgrounds admit a kinetic Yang-Mills term in the action of a vector multiplet. Here we find that the conformal Killing vector has to be Killing. We supplement the discussion with various appendices.

  9. Black holes in ω-deformed gauged N=8 supergravity

    International Nuclear Information System (INIS)

    Anabalón, Andrés; Astefanesei, Dumitru

    2014-01-01

    Motivated by the recently found 4-dimensional ω-deformed gauged supergravity, we investigate the black hole solutions within the single scalar field consistent truncations of this theory. We construct black hole solutions that have spherical, toroidal, and hyperbolic horizon topologies. The scalar field is regular everywhere outside the curvature singularity and the stress–energy tensor satisfies the null energy condition. When the parameter ω does not vanish, there is a degeneracy in the spectrum of black hole solutions for boundary conditions that preserve the asymptotic Anti-de Sitter symmetries. These boundary conditions correspond to multi-trace deformations in the dual field theory.

  10. Chern–Simons–Antoniadis–Savvidy forms and standard supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Izaurieta, F., E-mail: fizaurie@udec.cl; Salgado, P., E-mail: pasalgad@udec.cl; Salgado, S., E-mail: sesalgado@udec.cl

    2017-04-10

    In the context of the so called the Chern–Simons–Antoniadis–Savvidy (ChSAS) forms, we use the methods for FDA decomposition in 1-forms to construct a four-dimensional ChSAS supergravity action for the Maxwell superalgebra. On the another hand, we use the Extended Cartan Homotopy Formula to find a method that allows the separation of the ChSAS action into bulk and boundary contributions and permits the splitting of the bulk Lagrangian into pieces that reflect the particular subspace structure of the gauge algebra.

  11. AdS5 magnetized solutions in minimal gauged supergravity

    Directory of Open Access Journals (Sweden)

    Jose Luis Blázquez-Salcedo

    2017-08-01

    Full Text Available We construct a generalization of the AdS charged rotating black holes with two equal magnitude angular momenta in five-dimensional minimal gauged supergravity. In addition to the mass, electric charge and angular momentum, the new solutions possess an extra-parameter associated with a non-zero magnitude of the magnetic potential at infinity. In contrast with the known cases, these new black holes possess a non-trivial zero-horizon size limit which describes a one parameter family of spinning charged solitons. All configurations reported in this work approach asymptotically an AdS5 spacetime in global coordinates and are free of pathologies.

  12. 'Semi-realistic'F-term inflation model building in supergravity

    International Nuclear Information System (INIS)

    Kain, Ben

    2008-01-01

    We describe methods for building 'semi-realistic' models of F-term inflation. By semi-realistic we mean that they are built in, and obey the requirements of, 'semi-realistic' particle physics models. The particle physics models are taken to be effective supergravity theories derived from orbifold compactifications of string theory, and their requirements are taken to be modular invariance, absence of mass terms and stabilization of moduli. We review the particle physics models, their requirements and tools and methods for building inflation models

  13. Direct gauge mediation of uplifted metastable supersymmetry breaking in supergravity

    International Nuclear Information System (INIS)

    Maru, Nobuhito

    2010-01-01

    We propose a direct gauge mediation model based on an uplifted metastable supersymmetry (SUSY) breaking coupled to supergravity. A constant superpotential plays an essential role to fix the moduli as well as breaking SUSY and R symmetry and the cancellation of the cosmological constant. Gaugino masses are generated at leading order of SUSY breaking scale, and comparable to the sfermion masses as in the ordinary gauge mediation. The Landau pole problem for QCD coupling can be easily solved since more than half of messengers become superheavy, which are heavier than the grand unified theory (GUT) scale.

  14. Gravity mediation in 6d brane-world supergravity

    International Nuclear Information System (INIS)

    Lee, H.M.

    2005-09-01

    We consider the gravity-mediated SUSY breaking within the effective theory of six-dimensional brane-world supergravity. We construct the supersymmetric bulk-brane action by Noether method and find the nontrivial moduli coupling of the brane F- and D-terms. We find that the low energy Kaehler potential is not of sequestered form, so gravity mediation may occur at tree level. In moduli stabilization with anomaly effects included, the scalar soft mass squared can be positive at tree level and it can be comparable to the anomaly mediation. (orig.)

  15. A problem of the QCD axion in supergravity

    International Nuclear Information System (INIS)

    Endo, M.; Takahashi, F.; Tokyo Univ.; Yanagida, T.T.; Tokyo Univ.

    2007-12-01

    We point out that the QCD axion generally couples to all the gauge fields in nature through the Super-Weyl, Kaehler and sigma-model anomalies in supergravity. If supersymmetry is dynamically broken by the hidden-sector gauge interactions, the axion potential receives corrections due to the instanton in the hidden sector. We show that the supersymmetry breaking models are tightly constrained for the Peccei-Quinn mechanism to successfully solve the strong CP problem. In particular, the gravity mediation turns out to be strongly disfavored. (orig.)

  16. Black holes in ω-deformed gauged N=8 supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Anabalón, Andrés, E-mail: andres.anabalon@uai.cl [Departamento de Ciencias, Facultad de Artes Liberales y Facultad de Ingeniería y Ciencias, Universidad Adolfo Ibáñez, Av. Padre Hurtado 750, Viña del Mar (Chile); Université de Lyon, Laboratoire de Physique, UMR 5672, CNRS, École Normale Supérieure de Lyon, 46 allé d' Italie, F-69364 Lyon Cedex 07 (France); Astefanesei, Dumitru, E-mail: dumitru.astefanesei@ucv.cl [Instituto de Física, Pontificia Universidad Católica de Valparaíso, Casilla 4059, Valparaíso (Chile)

    2014-05-01

    Motivated by the recently found 4-dimensional ω-deformed gauged supergravity, we investigate the black hole solutions within the single scalar field consistent truncations of this theory. We construct black hole solutions that have spherical, toroidal, and hyperbolic horizon topologies. The scalar field is regular everywhere outside the curvature singularity and the stress–energy tensor satisfies the null energy condition. When the parameter ω does not vanish, there is a degeneracy in the spectrum of black hole solutions for boundary conditions that preserve the asymptotic Anti-de Sitter symmetries. These boundary conditions correspond to multi-trace deformations in the dual field theory.

  17. Black-Hole Attractors in N=1 Supergravity

    CERN Document Server

    Andrianopoli, L; Ferrara, Sergio; Trigiante, M; Andrianopoli, Laura; Auria, Riccardo D'; Ferrara, Sergio; Trigiante, Mario

    2007-01-01

    We study the attractor mechanism for N=1 supergravity coupled to vector and chiral multiplets and compute the attractor equations of these theories. These equations may have solutions depending on the choice of the holomorphic symmetric matrix f_{\\Lambda\\Sigma} which appears in the kinetic lagrangian of the vector sector. Models with non trivial electric-magnetic duality group which have or have not attractor behavior are exhibited. For a particular class of models, based on an N=1 reduction of homogeneous special geometries, the attractor equations are related to the theory of pure spinors.

  18. Duality in superspace and anomaly free supergravity: Some remarks

    International Nuclear Information System (INIS)

    D'Auria, R.; Fre, P.

    1988-01-01

    The authors show that the superspace formulation of anomaly free supergravity based on the 2-form B/sup (2)/ and the 6-form B/sup (6)/ are asymmetrical. B/sup (6)/ is the electric potential while B/sup (2)/ is the magnetic one. As a consequence, the Bianchi-identity associated with the B/sup (2)/ formulation is the in homogeneous Maxwell equation which provides a full account of the dynamics. The Bianchi identity associated with B/sup (6)/ is the homogeneous Maxwell equation: a mere identity which yields no information on the dynamics. It admits a universal ''offshell'' solution

  19. AMPK Signaling Involvement for the Repression of the IL-1β-Induced Group IIA Secretory Phospholipase A2 Expression in VSMCs.

    Directory of Open Access Journals (Sweden)

    Khadija El Hadri

    Full Text Available Secretory Phospholipase A2 of type IIA (sPLA2 IIA plays a crucial role in the production of lipid mediators by amplifying the neointimal inflammatory context of the vascular smooth muscle cells (VSMCs, especially during atherogenesis. Phenformin, a biguanide family member, by its anti-inflammatory properties presents potential for promoting beneficial effects upon vascular cells, however its impact upon the IL-1β-induced sPLA2 gene expression has not been deeply investigated so far. The present study was designed to determine the relationship between phenformin coupling AMP-activated protein kinase (AMPK function and the molecular mechanism by which the sPLA2 IIA expression was modulated in VSMCs. Here we find that 5-aminoimidazole-4-carboxamide-1-β-D-ribonucleotide (AICAR treatment strongly repressed IL-1β-induced sPLA2 expression at least at the transcriptional level. Our study reveals that phenformin elicited a dose-dependent inhibition of the sPLA2 IIA expression and transient overexpression experiments of constitutively active AMPK demonstrate clearly that AMPK signaling is involved in the transcriptional inhibition of sPLA2-IIA gene expression. Furthermore, although the expression of the transcriptional repressor B-cell lymphoma-6 protein (BCL-6 was markedly enhanced by phenformin and AICAR, the repression of sPLA2 gene occurs through a mechanism independent of BCL-6 DNA binding site. In addition we show that activation of AMPK limits IL-1β-induced NF-κB pathway activation. Our results indicate that BCL-6, once activated by AMPK, functions as a competitor of the IL-1β induced NF-κB transcription complex. Our findings provide insights on a new anti-inflammatory pathway linking phenformin, AMPK and molecular control of sPLA2 IIA gene expression in VSMCs.

  20. The Yang monopole in IIA superstring: multi-charge disease and enhançon cure

    International Nuclear Information System (INIS)

    Belhaj, Adil; Diaz, Pablo; Segui, Antonio

    2012-01-01

    A brane picture in type IIA superstring for the Yang monopole is reconsidered. It makes use of D2 and D4-branes wrapped on cycles in the K3 surface. When the model was first presented, some problems concerning the charges of the monopoles arose. In this paper, they are shown to be cured by the model itself. Surprisingly, the incompatibility between the multi-charge configuration and the spherical symmetry of the Yang monopole is seen in the brane description as the emergence of the enhançon shell and the fuzzy geometry. This consistency is deep and surprising, and is the point that triggered this work. It nontrivially relates a purely geometrical problem in ordinary spacetime with the emergence of noncommutative geometries. Besides, this paper includes an extended model for SO(4)-monopoles and a T-dual model in type IIB superstring. (paper)

  1. Manifesting enhanced cancellations in supergravity: integrands versus integrals

    Energy Technology Data Exchange (ETDEWEB)

    Bern, Zvi; Enciso, Michael; Parra-Martinez, Julio; Zeng, Mao [Mani L. Bhaumik Institute for Theoretical Physics, Department of Physics and Astronomy,University of California at Los Angeles,Los Angeles, CA 90095 (United States)

    2017-05-25

    Examples of ‘enhanced ultraviolet cancellations’ with no known standard-symmetry explanation have been found in a variety of supergravity theories. By examining one- and two-loop examples in four- and five-dimensional half-maximal supergravity, we argue that enhanced cancellations in general cannot be exhibited prior to integration. In light of this, we explore reorganizations of integrands into parts that are manifestly finite and parts that have poor power counting but integrate to zero due to integral identities. At two loops we find that in the large loop-momentum limit the required integral identities follow from Lorentz and SL(2) relabeling symmetry. We carry out a nontrivial check at four loops showing that the identities generated in this way are a complete set. We propose that at L loops the combination of Lorentz and SL(L) symmetry is sufficient for displaying enhanced cancellations when they happen, whenever the theory is known to be ultraviolet finite up to (L−1) loops.

  2. On the hidden maxwell superalgebra underlying D = 4 supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Penafiel, D.M. [Departamento de Fisica, Universidad de Concepcion (Chile); DISAT, Politecnico di Torino (Italy); Istituto Nazionale di Fisica Nucleare (INFN), Sezione di Torino (Italy); Ravera, L. [DISAT, Politecnico di Torino (Italy); Istituto Nazionale di Fisica Nucleare (INFN), Sezione di Torino (Italy)

    2017-09-15

    In this work, we expand the hidden AdS-Lorentz superalgebra underlying D = 4 supergravity, reaching a (hidden) Maxwell superalgebra. The latter can be viewed as an extension involving cosmological constant of the superalgebra underlying D = 4 supergravity in flat spacetime. We write the Maurer-Cartan equations in this context and we find some interesting extensions of the antisymmetric 3-form A{sup (3)} appearing in the Free Differential Algebra in Minkowski space. The structure of Free Differential Algebras is obtained by considering the zero curvature equations. We write the parametrization of A{sup (3)} in terms of 1-forms and we rend the topological features of its extensions manifest. We interestingly find out that the structure of these extensions, and consequently the structure of the corresponding boundary contribution dA{sup (3)}, strongly depends on the form of the extra fermionic generator appearing in the hidden Maxwell superalgebra. The model we develop in this work is defined in an enlarged superspace with respect to the ordinary one, and the extra bosonic and fermionic 1-forms required for the closure of the hidden Maxwell superalgebra must be considered as physical fields in this enlarged superspace. (copyright 2017 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  3. On the underlying gauge group structure of D=11 supergravity

    International Nuclear Information System (INIS)

    Bandos, I.A.; Azcarraga, J.A. de; Izquierdo, J.M.; Picon, M.; Varela, O.

    2004-01-01

    The underlying gauge group structure of D=11 supergravity is revisited. It may be described by a one-parametric family of Lie supergroups Σ-bar (s)x-bar SO(1,10), s 0. The family of superalgebras E-bar (s) associated to Σ-bar (s) is given by a family of extensions of the M-algebra {Pa,Qα,Zab,Za1...a5} by an additional fermionic central charge Qα'. The Chevalley-Eilenberg four-cocycle ω4∼Πα-bar Πβ-bar Πa-bar ΠbΓabαβ on the standard D=11 supersymmetry algebra may be trivialized on E-bar (s), and this implies that the three-form field A3 of D=11 supergravity may be expressed as a composite of the Σ-bar (s) one-form gauge fields ea, ψα, Bab, Ba1...a5 and ηα. Two superalgebras of E-bar (s) recover the two earlier D'Auria and Fre decompositions of A3. Another member of E-bar (s) allows for a simpler composite structure for A3 that does not involve the Ba1...a5 field. Σ-bar (s) is a deformation of Σ-bar (0), which is singularized by having an enhanced Sp(32) (rather than just SO(1,10)) automorphism symmetry and by being an expansion of OSp(1 vertical bar 32)

  4. N=2 vacua in electrically gauged N=4 supergravities

    Energy Technology Data Exchange (ETDEWEB)

    Horst, Christoph

    2013-06-15

    In this thesis we study N= 2 vacua in gauged N=4 supergravity theories in fourdimensional spacetime. Using the embedding tensor formalism that describes general consistent magnetic gaugings of an ungauged N=4 matter-coupled supergravity theory in a symplectic frame with SO(1,1) x SO(6,n) off-shell symmetry we formulate necessary conditions for partial supersymmetry breaking and find that the Killing spinor equations can be solved for the embedding tensor components. Subsequently, we show that the classification of theories that allow for vacua with partial supersymmetry amounts to solving a system of purely algebraic quadratic equations. Then, we restrict ourselves to the class of purely electric gaugings and explicitly construct a class of consistent super-Higgs mechanisms and study its properties. In particular, we find that the spectrum fills complete N=2 supermultiplets that are either massless or BPS. Furthermore, we demonstrate that (modulo an abelian Lie algebra) arbitrary unbroken gauge Lie algebras can be realized provided that the number of N=4 vector multiplets is sufficiently large. Finally, we compute the relevant terms of the effective action below the scale of partial supersymmetry breaking and argue that the special Kaehler manifold for the scalars of the N=2 vector multiplets has to be in the unique series of special Kaehler product manifolds.

  5. Spontaneous SUSY breaking without R symmetry in supergravity

    Science.gov (United States)

    Maekawa, Nobuhiro; Omura, Yuji; Shigekami, Yoshihiro; Yoshida, Manabu

    2018-03-01

    We discuss spontaneous supersymmetry (SUSY) breaking in a model with an anomalous U (1 )A symmetry. In this model, the size of the each term in the superpotential is controlled by the U (1 )A charge assignment and SUSY is spontaneously broken via the Fayet-Iliopoulos of U (1 )A at the metastable vacuum. In the global SUSY analysis, the gaugino masses become much smaller than the sfermion masses, because an approximate R symmetry appears at the SUSY breaking vacuum. In this paper, we show that gaugino masses can be as large as gravitino mass, taking the supergravity effect into consideration. This is because the R symmetry is not imposed so that the constant term in the superpotential, which is irrelevant to the global SUSY analysis, largely contributes to the soft SUSY breaking terms in the supergravity. As the mediation mechanism, we introduce the contributions of the field not charged under U (1 )A and the moduli field to cancel the anomaly of U (1 )A. We comment on the application of our SUSY breaking scenario to the grand unified theory.

  6. BFV-BRST quantization of 2D supergravity

    International Nuclear Information System (INIS)

    Fujiwara, T.; Igarashi, Y.; Kuriki, R.; Tabei, T.

    1995-02-01

    Two-dimensional supergravity theory is quantized as an anomalous gauge theory. In the Batalin-Fradkin (BF) formalism, the anomaly-canceling super-Liouville fields are introduced to identify the original second-class constrained system with a gauge-fixed version of a first-class system. The BFV-BRST quantization applies to formulate the theory in the most general class of gauges. A local effective action constructed in the configuration space contains two super-Liouville actions; one is a noncovariant but local functional written only in terms of 2D supergravity fields, and the other contains the super-Liouville fields canceling the super-Weyl anomaly. Auxiliary fields for the Liouville and the gravity super-multiplets are introduced to make the BRST algebra close off-shell. Inclusion of them turns out to be essentially important especially in the super-lightcone gauge-fixing, where the super-curvature equations (δ - 3 g ++ =δ - 2 χ ++ =0) are obtained as a result of BRST invariance of the theory. Our approach reveals the origin of the OSp (1,2) current algebra symmetry in a transparent manner. (author)

  7. Group-geometric methods in supergravity and superstring theories

    International Nuclear Information System (INIS)

    Castellani, L.

    1992-01-01

    The purpose of this paper is to give a brief and pedagogical account of the group-geometric approach to (super)gravity and superstring theories. The authors summarize the main ideas and apply them to selected examples. Group geometry provides a natural and unified formulation of gravity and gauge theories. The invariance of both are interpreted as diffeomorphisms on a suitable group manifold. This geometrical framework has a fruitful output, in that it provides a systematic algorithm for the gauging of Lie algebras and the construction of (super)gravity or (super)string Lagrangians. The basic idea is to associate fundamental fields to the group generators. This is done by considering first a basis of tangent vectors on the group manifold. These vectors close on the same algebra as the abstract group generators. The dual basis, i.e. the vielbeins (cotangent basis of one-forms) is then identified with the set of fundamental fields. Thus, for example, the vielbein V a and the spin connection ω ab of ordinary Einstein-Cartan gravity are seen as the duals of the tangent vectors corresponding to translations and Lorentz rotations, respectively

  8. Geometric supergravity in D = 11 and its hidden supergroup

    International Nuclear Information System (INIS)

    D'Auria, R.; Fre, P.

    1982-01-01

    In this paper we address two questions: the geometrical formulation of D=11 supergravity and the derivation of the super Lie algebra it is based on. The solutions of the two problems are intimately related and are obtained via the introduction of the new concept of a Cartan integrable system described in this paper. The previously developed group manifold framework can be naturally extended to a Cartan integrable system manifold approach. Within this scheme we obtain a geometric action for D=11 supergravity based on a suitable Cartan system. This latter turns out to be compact description of a two-element class of supergroups containing besides Lorentz Jsub(ab), translation Psub(a) and ordinary supersymmetry Q, the following extra generators: two- and five-index skew-symmetric tensors Zsub(a1a2)Zsub(a1...a5) and a further spinorial charge Q'. Q' commutes with itself and everyhting else except Jsub(ab). It appears in the commutators of Q with Psub(a),Zsub(a1a2),Zsub(a1...a5). (orig.)

  9. On gauged maximal d  =  8 supergravities

    Science.gov (United States)

    Lasso Andino, Óscar; Ortín, Tomás

    2018-04-01

    We study the gauging of maximal d  =  8 supergravity using the embedding tensor formalism. We focus on SO(3) gaugings, study all the possible choices of gauge fields and construct explicitly the bosonic actions (including the complicated Chern–Simons terms) for all these choices, which are parametrized by a parameter associated to the 8-dimensional SL(2, {R}) duality group that relates all the possible choices which are, ultimately, equivalent from the purely 8-dimensional point of view. Our result proves that the theory constructed by Salam and Sezgin by Scherk–Schwarz compactification of d  =  11 supergravity and the theory constructed in Alonso-Alberca (2001 Nucl. Phys. B 602 329) by dimensional reduction of the so called ‘massive 11-dimensional supergravity’ proposed by Meessen and Ortín in (1999 Nucl. Phys. B 541 195) are indeed related by an SL(2, {R}) duality even though they have two completely different 11-dimensional origins.

  10. Isometries, gaugings and N=2 supergravity decoupling

    Energy Technology Data Exchange (ETDEWEB)

    Antoniadis, Ignatios [Laboratoire de Physique Théorique et Hautes Energies, Sorbonne Universités,CNRS UMR 7589, UPMC Paris 6, 4 place Jussieu, 75005 Paris (France); Albert Einstein Center for Fundamental Physics, Institute for Theoretical Physics,University of Bern,Sidlerstrasse 5, 3012 Bern (Switzerland); Derendinger, Jean-Pierre [Albert Einstein Center for Fundamental Physics, Institute for Theoretical Physics,University of Bern,Sidlerstrasse 5, 3012 Bern (Switzerland); Petropoulos, P. Marios [Centre de Physique Théorique, Ecole Polytechnique, CNRS UMR 7644, Université Paris-Saclay,91128 Palaiseau Cedex (France); Laboratoire de Physique Théorique et Hautes Energies, Sorbonne Universités,CNRS UMR 7589, UPMC Paris 6, 4 place Jussieu, 75005 Paris (France); Siampos, Konstantinos [Albert Einstein Center for Fundamental Physics, Institute for Theoretical Physics,University of Bern,Sidlerstrasse 5, 3012 Bern (Switzerland)

    2016-11-28

    We study off-shell rigid limits for the kinetic and scalar-potential terms of a single N=2 hypermultiplet. In the kinetic term, these rigid limits establish relations between four-dimensional quaternion-Kähler and hyper-Kähler target spaces with symmetry. The scalar potential is obtained by gauging the graviphoton along an isometry of the quaternion-Kähler space. The rigid limits unveil two distinct cases. A rigid N=2 theory on Minkowski or on AdS{sub 4} spacetime, depending on whether the isometry is translational or rotational respectively. We apply these results to the quaternion-Kähler space with Heisenberg⋉U(1) isometry, which describes the universal hypermultiplet at type-II string one-loop.

  11. Supergravity contributions to inflation in models with non-minimal coupling to gravity

    Energy Technology Data Exchange (ETDEWEB)

    Das, Kumar; Dutta, Koushik [Theory Division, Saha Institute of Nuclear Physics, 1/AF Saltlake, Kolkata 700064 (India); Domcke, Valerie, E-mail: kumar.das@saha.ac.in, E-mail: valerie.domcke@apc.univ-paris7.fr, E-mail: koushik.dutta@saha.ac.in [AstroParticule et Cosmologie (APC), Paris Centre for Cosmological Physics (PCCP), Université Paris Diderot, 75013 Paris (France)

    2017-03-01

    This paper provides a systematic study of supergravity contributions relevant for inflationary model building in Jordan frame supergravity. In this framework, canonical kinetic terms in the Jordan frame result in the separation of the Jordan frame scalar potential into a tree-level term and a supergravity contribution which is potentially dangerous for sustaining inflation. We show that if the vacuum energy necessary for driving inflation originates dominantly from the F-term of an auxiliary field (i.e. not the inflaton), the supergravity corrections to the Jordan frame scalar potential are generically suppressed. Moreover, these supergravity contributions identically vanish if the superpotential vanishes along the inflationary trajectory. On the other hand, if the F-term associated with the inflaton dominates the vacuum energy, the supergravity contributions are generically comparable to the globally supersymmetric contributions. In addition, the non-minimal coupling to gravity inherent to Jordan frame supergravity significantly impacts the inflationary model depending on the size and sign of this coupling. We discuss the phenomenology of some representative inflationary models, and point out the relation to the recently much discussed cosmological 'attractor' models.

  12. Supergravity contributions to inflation in models with non-minimal coupling to gravity

    International Nuclear Information System (INIS)

    Das, Kumar; Dutta, Koushik; Domcke, Valerie

    2017-01-01

    This paper provides a systematic study of supergravity contributions relevant for inflationary model building in Jordan frame supergravity. In this framework, canonical kinetic terms in the Jordan frame result in the separation of the Jordan frame scalar potential into a tree-level term and a supergravity contribution which is potentially dangerous for sustaining inflation. We show that if the vacuum energy necessary for driving inflation originates dominantly from the F-term of an auxiliary field (i.e. not the inflaton), the supergravity corrections to the Jordan frame scalar potential are generically suppressed. Moreover, these supergravity contributions identically vanish if the superpotential vanishes along the inflationary trajectory. On the other hand, if the F-term associated with the inflaton dominates the vacuum energy, the supergravity contributions are generically comparable to the globally supersymmetric contributions. In addition, the non-minimal coupling to gravity inherent to Jordan frame supergravity significantly impacts the inflationary model depending on the size and sign of this coupling. We discuss the phenomenology of some representative inflationary models, and point out the relation to the recently much discussed cosmological 'attractor' models.

  13. Is chloroplastic class IIA aldolase a marine enzyme?

    Science.gov (United States)

    Miyasaka, Hitoshi; Ogata, Takeru; Tanaka, Satoshi; Ohama, Takeshi; Kano, Sanae; Kazuhiro, Fujiwara; Hayashi, Shuhei; Yamamoto, Shinjiro; Takahashi, Hiro; Matsuura, Hideyuki; Hirata, Kazumasa

    2016-01-01

    Expressed sequence tag analyses revealed that two marine Chlorophyceae green algae, Chlamydomonas sp. W80 and Chlamydomonas sp. HS5, contain genes coding for chloroplastic class IIA aldolase (fructose-1, 6-bisphosphate aldolase: FBA). These genes show robust monophyly with those of the marine Prasinophyceae algae genera Micromonas, Ostreococcus and Bathycoccus, indicating that the acquisition of this gene through horizontal gene transfer by an ancestor of the green algal lineage occurred prior to the divergence of the core chlorophytes (Chlorophyceae and Trebouxiophyceae) and the prasinophytes. The absence of this gene in some freshwater chlorophytes, such as Chlamydomonas reinhardtii, Volvox carteri, Chlorella vulgaris, Chlorella variabilis and Coccomyxa subellipsoidea, can therefore be explained by the loss of this gene somewhere in the evolutionary process. Our survey on the distribution of this gene in genomic and transcriptome databases suggests that this gene occurs almost exclusively in marine algae, with a few exceptions, and as such, we propose that chloroplastic class IIA FBA is a marine environment-adapted enzyme. This hypothesis was also experimentally tested using Chlamydomonas W80, for which we found that the transcript levels of this gene to be significantly lower under low-salt (that is, simulated terrestrial) conditions. Expression analyses of transcriptome data for two algae, Prymnesium parvum and Emiliania huxleyi, taken from the Sequence Read Archive database also indicated that the expression of this gene under terrestrial conditions (low NaCl and low sulfate) is significantly downregulated. Thus, these experimental and transcriptome data provide support for our hypothesis. PMID:27058504

  14. Higgs mechanism and cosmological constant in N = 1 supergravity with inflaton in a vector multiplet

    Energy Technology Data Exchange (ETDEWEB)

    Aldabergenov, Yermek [Tokyo Metropolitan University, Department of Physics, Tokyo (Japan); Ketov, Sergei V. [Tokyo Metropolitan University, Department of Physics, Tokyo (Japan); The University of Tokyo, Kavli Institute for the Physics and Mathematics of the Universe (IPMU), Chiba (Japan); Tomsk Polytechnic University, Institute of Physics and Technology, Tomsk (Russian Federation)

    2017-04-15

    The N = 1 supergravity models of cosmological inflation with an inflaton belonging to a massive vector multiplet and spontaneous SUSY breaking after inflation are reformulated as the supersymmetric U(1) gauge theories of a massless vector superfield interacting with the Higgs and Polonyi chiral superfields, all coupled to supergravity. The U(1) gauge sector is identified with the U(1) gauge fields of the super-GUT coupled to supergravity, whose gauge group has a U(1) factor. A positive cosmological constant (dark energy) is included. The scalar potential is calculated, and its de Sitter vacuum solution is found to be stable. (orig.)

  15. A natural solution to the μ-problem in supergravity theories

    International Nuclear Information System (INIS)

    Giudice, G.F.; Masiero, A.

    1988-01-01

    We propose a 'natural' way to avoid the introduction by hand of a small mass scale μ in the observable sector of N=1 supergravity theories. In our approach, μ automatically arises from the general couplings of broken supergravity. In this way, all low energy mass parameters arise only from supergravity breaking and, in particular, SU(2)xU(1) is left unbroken in the limit of exact supersymmetry. Our solution of the μ-problem presents interesting connections with the strong CP puzzle through the implementation of symmetries a la Peccei and Quinn. (orig.)

  16. Particle physics models of inflation in supergravity and grand unification

    International Nuclear Information System (INIS)

    Kostka, Philipp Manuel

    2010-01-01

    In the first part of this thesis, we study classes of hybrid and chaotic inflation models in four-dimensional N=1 supergravity. Therein, the η-problem can be resolved relying on fundamental symmetries in the Kaehler potential. Concretely, we investigate explicit realizations of superpotentials, in which the flatness of the inflaton potential is protected at tree level by a shift symmetry or a Heisenberg symmetry in the Kaehler potential. In the latter case, the associated modulus field can be stabilized during inflation by supergravity effects. In the context of hybrid inflation, a novel class of models, to which we refer as ''tribrid inflation,'' turns out to be particularly compatible with such symmetry solutions to the η-problem. Radiative corrections due to operators in the superpotential, which break the respective symmetry, generate the required small slope of the inflaton potential. Additional effective operators in the Kaehler potential can reduce the predicted spectral index so that it agrees with latest observational data. Within a model of chaotic inflation in supergravity with a quadratic potential, we apply the Heisenberg symmetry to allow for viable inflation with super-Planckian field values, while the associated modulus is stabilized. We show that radiative corrections are negligible in this context. In the second part, the tribrid inflation models are extended to realize gauge non-singlet inflation. This is applied to the matter sector of supersymmetric Grand Unified Theories based on the Pati-Salam gauge group. For the specific scenario in which the right-handed sneutrino is the inflaton, we study the scalar potential in a D-flat valley. We show that despite potentially dangerous two-loop corrections, the required flatness of the potential can be maintained. The reason for this is the strong suppression of gauge interactions of the inflaton field due to its symmetry breaking vacuum expectation value. In addition, the production of stable

  17. Particle physics models of inflation in supergravity and grand unification

    Energy Technology Data Exchange (ETDEWEB)

    Kostka, Philipp Manuel

    2010-12-03

    In the first part of this thesis, we study classes of hybrid and chaotic inflation models in four-dimensional N=1 supergravity. Therein, the {eta}-problem can be resolved relying on fundamental symmetries in the Kaehler potential. Concretely, we investigate explicit realizations of superpotentials, in which the flatness of the inflaton potential is protected at tree level by a shift symmetry or a Heisenberg symmetry in the Kaehler potential. In the latter case, the associated modulus field can be stabilized during inflation by supergravity effects. In the context of hybrid inflation, a novel class of models, to which we refer as ''tribrid inflation,'' turns out to be particularly compatible with such symmetry solutions to the {eta}-problem. Radiative corrections due to operators in the superpotential, which break the respective symmetry, generate the required small slope of the inflaton potential. Additional effective operators in the Kaehler potential can reduce the predicted spectral index so that it agrees with latest observational data. Within a model of chaotic inflation in supergravity with a quadratic potential, we apply the Heisenberg symmetry to allow for viable inflation with super-Planckian field values, while the associated modulus is stabilized. We show that radiative corrections are negligible in this context. In the second part, the tribrid inflation models are extended to realize gauge non-singlet inflation. This is applied to the matter sector of supersymmetric Grand Unified Theories based on the Pati-Salam gauge group. For the specific scenario in which the right-handed sneutrino is the inflaton, we study the scalar potential in a D-flat valley. We show that despite potentially dangerous two-loop corrections, the required flatness of the potential can be maintained. The reason for this is the strong suppression of gauge interactions of the inflaton field due to its symmetry breaking vacuum expectation value. In addition, the

  18. The antitumor natural product tanshinone IIA inhibits protein kinase C and acts synergistically with 17-AAG.

    Science.gov (United States)

    Lv, Chao; Zeng, Hua-Wu; Wang, Jin-Xin; Yuan, Xing; Zhang, Chuang; Fang, Ting; Yang, Pei-Ming; Wu, Tong; Zhou, Yu-Dong; Nagle, Dale G; Zhang, Wei-Dong

    2018-02-07

    Tanshinone IIA (Tan IIA), the primary bioactive compound derived from the traditional Chinese medicine (TCM) Salvia miltiorrhiza Bunge, has been reported to possess antitumor activity. However, its antitumor mechanisms are not fully understood. To resolve the potential antitumor mechanism(s) of Tan IIA, its gene expression profiles from our database was analyzed by connectivity map (CMAP) and the CMAP-based mechanistic predictions were confirmed/validated in further studies. Specifically, Tan IIA inhibited total protein kinase C (PKC) activity and selectively suppressed the expression of cytosolic and plasma membrane PKC isoforms ζ and ε. The Ras/MAPK pathway that is closely regulated by the PKC signaling is also inhibited by Tan IIA. While Tan IIA did not inhibit heat shock protein 90 (Hsp90), it synergistically enhanced the antitumor efficacy of the Hsp90 inhibitors 17-AAG and ganetespib in human breast cancer MCF-7 cells. In addition, Tan IIA significantly inhibited PI3K/Akt/mTOR signaling, and induced both cell cycle arrest and autophagy. Collectively, these studies provide new insights into the molecular mechanisms responsible for antitumor activity of Tan IIA.

  19. Secretory Phospholipase A2-IIA and Cardiovascular Disease: A Mendelian Randomization Study

    NARCIS (Netherlands)

    Holmes, Michael V.; Simon, Tabassome; Exeter, Holly J.; Folkersen, Lasse; Asselbergs, Folkert W.; Guardiola, Montse; Cooper, Jackie A.; Palmen, Jutta; Hubacek, Jaroslav A.; Carruthers, Kathryn F.; Horne, Benjamin D.; Brunisholz, Kimberly D.; Mega, Jessica L.; van Iperen, Erik P. A.; Li, Mingyao; Leusink, Maarten; Trompet, Stella; Verschuren, Jeffrey J. W.; Hovingh, G. Kees; Dehghan, Abbas; Nelson, Christopher P.; Kotti, Salma; Danchin, Nicolas; Scholz, Markus; Haase, Christiane L.; Rothenbacher, Dietrich; Swerdlow, Daniel I.; Kuchenbaecker, Karoline B.; Staines-Urias, Eleonora; Goel, Anuj; van 't Hooft, Ferdinand; Gertow, Karl; de Faire, Ulf; Panayiotou, Andrie G.; Tremoli, Elena; Baldassarre, Damiano; Veglia, Fabrizio; Holdt, Lesca M.; Beutner, Frank; Gansevoort, Ron T.; Navis, Gerjan J.; Mateo Leach, Irene; Breitling, Lutz P.; Brenner, Hermann; Thiery, Joachim; Dallmeier, Dhayana; Franco-Cereceda, Anders; Boer, Jolanda M. A.; Stephens, Jeffrey W.; Hofker, Marten H.; Tedgui, Alain; Hofman, Albert; Uitterlinden, André G.; Adamkova, Vera; Pitha, Jan; Onland-Moret, N. Charlotte; Cramer, Maarten J.; Nathoe, Hendrik M.; Spiering, Wilko; Klungel, Olaf H.; Kumari, Meena; Whincup, Peter H.; Morrow, David A.; Braund, Peter S.; Hall, Alistair S.; Olsson, Anders G.; Doevendans, Pieter A.; Trip, Mieke D.; Tobin, Martin D.; Hamsten, Anders; Watkins, Hugh; Koenig, Wolfgang; Nicolaides, Andrew N.; Teupser, Daniel; Day, Ian N. M.; Carlquist, John F.; Gaunt, Tom R.; Ford, Ian; Sattar, Naveed; Tsimikas, Sotirios; Schwartz, Gregory G.; Lawlor, Debbie A.; Morris, Richard W.; Sandhu, Manjinder S.; Poledne, Rudolf; Maitland-van der Zee, Anke H.; Khaw, Kay-Tee; Keating, Brendan J.; van der Harst, Pim; Price, Jackie F.; Mehta, Shamir R.; Yusuf, Salim; Witteman, Jaqueline C. M.; Franco, Oscar H.; Jukema, J. Wouter; de Knijff, Peter; Tybjaerg-Hansen, Anne; Rader, Daniel J.; Farrall, Martin; Samani, Nilesh J.; Kivimaki, Mika; Fox, Keith A. A.; Humphries, Steve E.; Anderson, Jeffrey L.; Boekholdt, S. Matthijs; Palmer, Tom M.; Eriksson, Per; Paré, Guillaume; Hingorani, Aroon D.; Sabatine, Marc S.; Mallat, Ziad; Casas, Juan P.; Talmud, Philippa J.

    2013-01-01

    This study sought to investigate the role of secretory phospholipase A2 (sPLA2)-IIA in cardiovascular disease. Higher circulating levels of sPLA2-IIA mass or sPLA2 enzyme activity have been associated with increased risk of cardiovascular events. However, it is not clear if this association is

  20. Anti-Inflammatory and Immunomodulatory Mechanism of Tanshinone IIA for Atherosclerosis

    Directory of Open Access Journals (Sweden)

    Zhuo Chen

    2014-01-01

    Full Text Available Tanshinone IIA (Tan II A is widely used in the treatment of cardiovascular diseases as an active component of Salvia miltiorrhiza Bunge. It has been demonstrated to have pleiotropic effects for atherosclerosis. From the anti-inflammatory and immunomodulatory mechanism perspective, this paper reviewed major progresses of Tan IIA in antiatherosclerosis research, including immune cells, antigens, cytokines, and cell signaling pathways.

  1. Disruption of the Class IIa HDAC Corepressor Complex Increases Energy Expenditure and Lipid Oxidation

    Directory of Open Access Journals (Sweden)

    Vidhi Gaur

    2016-09-01

    Full Text Available Drugs that recapitulate aspects of the exercise adaptive response have the potential to provide better treatment for diseases associated with physical inactivity. We previously observed reduced skeletal muscle class IIa HDAC (histone deacetylase transcriptional repressive activity during exercise. Here, we find that exercise-like adaptations are induced by skeletal muscle expression of class IIa HDAC mutants that cannot form a corepressor complex. Adaptations include increased metabolic gene expression, mitochondrial capacity, and lipid oxidation. An existing HDAC inhibitor, Scriptaid, had similar phenotypic effects through disruption of the class IIa HDAC corepressor complex. Acute Scriptaid administration to mice increased the expression of metabolic genes, which required an intact class IIa HDAC corepressor complex. Chronic Scriptaid administration increased exercise capacity, whole-body energy expenditure and lipid oxidation, and reduced fasting blood lipids and glucose. Therefore, compounds that disrupt class IIa HDAC function could be used to enhance metabolic health in chronic diseases driven by physical inactivity.

  2. Eleven-dimensional supergravity from filtered subdeformations of the Poincaré superalgebra

    International Nuclear Information System (INIS)

    Figueroa-O’Farrill, José; Santi, Andrea

    2016-01-01

    We summarise recent results concerning the classification of filtered deformations of graded subalgebras of the Poincaré superalgebra in eleven dimensions, highlighting what could be considered a novel Lie-algebraic derivation of eleven-dimensional supergravity. (paper)

  3. Annecy meeting on supersymmetry and supergravity at LAPP, Jannary 10-12, 1983

    International Nuclear Information System (INIS)

    Sorba, P.; Stora, R.

    1983-01-01

    A collection of brief summaries of the talks delivered during the meeting is presented. This gives a good idea of what is going on. The contributions have been gathered under four titles: supersymmetry, supersymmetric guts, phenomenology of supersymmetry, supergravity

  4. BPS-kink and more global solutions of the Chern-Simons (super)gravity term

    International Nuclear Information System (INIS)

    Grumiller, D.

    2004-01-01

    We study the supersymmetry of the Kaluza-Klein reduced gravitational Chern-Simons term in two dimensions and propose supergravity transformations that allow for some supersymmetry of the kink solution. (author)

  5. Inflation via Gravitino Condensation in Dynamically Broken Supergravity

    CERN Document Server

    Alexandre, Jean; Mavromatos, Nick E

    2015-01-01

    Gravitino-condensate-induced inflation via the super-Higgs effect is a UV-motivated scenario for both inflating the early universe and breaking local supersymmetry dynamically, entirely independent of any coupling to external matter. As an added benefit, this also removes the (as of yet unobserved) massless Goldstino associated to global supersymmetry breaking from the particle spectrum. In this review we detail the pertinent properties and outline previously hidden details of the various steps required in this context in order to make contact with current inflationary phenomenology. The class of models of SUGRA we use to exemplify our approach are minimal four-dimensional N=1 supergravity and conformal extensions thereof (with broken conformal symmetry). Therein, the gravitino condensate itself can play the role of the inflaton, however the requirement of slow-roll necessitates unnaturally large values of the wave-function renormalisation. Nevertheless, there is an alternative scenario that may provide Staro...

  6. Universal contributions to scalar masses from five dimensional supergravity

    CERN Document Server

    Dudas, Emilian

    2012-01-01

    We compute the effective Kahler potential for matter fields in warped compactifications, starting from five dimensional gauged supergravity, as a function of the matter fields localization. We show that truncation to zero modes is inconsistent and the tree-level exchange of the massive gravitational multiplet is needed for consistency of the four-dimensional theory. In addition to the standard Kahler coming from dimensional reduction, we find the quartic correction coming from integrating out the gravity multiplet. We apply our result to the computation of scalar masses, by assuming that the SUSY breaking field is a bulk hypermultiplet. In the limit of extreme opposite localization of the matter and the spurion fields, we find zero scalar masses, consistent with sequestering arguments. Surprisingly enough, for all the other cases the scalar masses are tachyonic. This suggests the holographic interpretation that a CFT sector always generates operators contributing in a tachyonic way to scalar masses. Viability...

  7. 2D supergravity and its connection to integrable models

    International Nuclear Information System (INIS)

    Arnaudov, L.N.; Prodanov, E.M.; Rashkov, R.C.

    1993-05-01

    In the recent work two different approaches for obtaining the covariant W 2 -action of 2-d quantum supergravity are considered. The first one is based on Hamiltonian reduction of flat Osp(2/1) connection in holomorphic polarization. Adding extra degrees of freedom with the help of gauging procedure the W 2 -action and the superconformal identities are obtained. It is shown that the super Virasoro transformations preserve the form of the Lax connection and therefore are symmetries of the sKdV equations. In the second approach starting with Chern-Simons theory and using non-canonical polarization the zero-curvature condition entails the same results. (author). 7 refs

  8. Nonlinear symmetries of black hole entropy in gauged supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Klemm, Dietmar [Dipartimento di Fisica, Università di Milano,and INFN, Sezione di Milano,Via Celoria 16, I-20133 Milano (Italy); Marrani, Alessio [Museo Storico della Fisica e Centro Studi e Ricerche ‘Enrico Fermi’,Via Panisperna 89A, I-00184 Roma (Italy); Dipartimento di Fisica e Astronomia ‘Galileo Galilei’, Università di Padova,and INFN, Sezione di Padova,Via Marzolo 8, I-35131 Padova (Italy); Petri, Nicolò; Rabbiosi, Marco [Dipartimento di Fisica, Università di Milano,and INFN, Sezione di Milano,Via Celoria 16, I-20133 Milano (Italy)

    2017-04-04

    Freudenthal duality in N=2, D=4 ungauged supergravity is generated by an anti-involutive operator that acts on the electromagnetic fluxes, and results to be a symmetry of the Bekenstein-Hawking entropy. We show that, with a suitable extension, this duality can be generalized to the abelian gauged case as well, even in presence of hypermultiplets. By defining Freudenthal duality along the scalar flow, one can prove that two configurations of charges and gaugings linked by the Freudenthal operator share the same set of values of the scalar fields at the black hole horizon. Consequently, Freudenthal duality is promoted to a nonlinear symmetry of the black hole entropy. We explicitly show this invariance for the model with prepotential F=−iX{sup 0}X{sup 1} and Fayet-Iliopoulos gauging.

  9. Naturalness reach of the large hadron collider in minimal supergravity

    International Nuclear Information System (INIS)

    Allanach, B.C.; Hetherington, J.P.J.; Parker, M.A.; Webber, B.R.

    2000-01-01

    We re-analyse the prospects of discovering supersymmetry at the LHC, in order to re-express coverage in terms of a fine-tuning parameter and to extend the analysis to scalar masses (m 0 ) above 2 TeV. We use minimal supergravity (mSUGRA) unification assumptions for the SUSY breaking parameters. Such high values of m 0 have recently been found to have a focus point, leading to relatively low fine-tuning. In addition, improvements in the simulations since the last study mean that this region no longer lacks radiative electroweak symmetry breaking. The best fine tuning reach is found in a mono-leptonic channel, where for μ>0, A 0 =0 and tan β=10 (corresponding to the focus point), all points in mSUGRA with m 0 0 , mSUGRA does not evade detection provided the gaugino mass parameter M 1/2 < 460 GeV. (author)

  10. Confronting hybrid inflation in supergravity with CMB data

    International Nuclear Information System (INIS)

    Jeannerot, Rachel; Postma, Marieke

    2005-01-01

    F-term GUT inflation coupled to N = 1 supergravity is confronted with CMB data. Corrections to the string mass-per-unit-length away from the Bogomolny limit are taken into account. We find that a superpotential coupling 10 -7 /N∼ -2 /N, with N the dimension of the Higgs-representation, is still compatible with the data. The parameter space is enlarged in warm inflation, as well as in the curvaton and inhomogeneous reheat scenario. F-strings formed at the end of P-term inflation are also considered. Because these strings satisfy the Bogomolny bound the bounds are stronger: the gauge coupling is constrained to the range 10 -7 -4

  11. CERN Winter School on Supergravity, Strings, and Gauge Theory 2010

    CERN Multimedia

    CERN. Geneva

    2010-01-01

    The CERN Winter School on Supergravity, Strings, and Gauge Theory is the analytic continuation of the yearly training school of the former EC-RTN string network "Constituents, Fundamental Forces and Symmetries of the Universe". The 2010 edition of the school is supported and organized by the CERN Theory Divison, and will take place from Monday January 25 to Friday January 29, at CERN. As its predecessors, this school is meant primarily for training of doctoral students and young postdoctoral researchers in recent developments in theoretical high-energy physics and string theory. The programme of the school will consist of five series of pedagogical lectures, complemented by tutorial discussion sessions in the afternoons. Previous schools in this series were organized in 2005 at SISSA in Trieste, and in 2006, 2007, 2008, and 2009 at CERN, Geneva. Other similar schools have been organized in the past by the former related RTN network "The Quantum Structure of Spacetime and the Geometric Nature of Fundamenta...

  12. Inflation and leptogenesis from right handed sneutrinos in supergravity

    International Nuclear Information System (INIS)

    Peloso, Marco

    2016-01-01

    We describe a supergravity model of inflation where the inflaton is identified with one linerar combination of two right handed sneutrino fields. The potential along the inflationary trajectory is flatter than that of massive chaotic inflation, resulting in a detectable but not ruled out tensor-to-scalar ratio r. In general, the potential for the two sneutrinos has complex phases. As a result, the two neutrinos can develop a nonvanishing lepton charge through a simple modification of the Affleck-Dine mechanism. [This talk summarizes the work of Evans, Ghergetta, and Peloso, Phys. Rev. D 92, no. 2, 021303 (2015) (Ref. 1). Please refer to that work for details and for a more comprehensive list of references.

  13. R-current six-point correlators in AdS5 supergravity

    International Nuclear Information System (INIS)

    Bartels, J.; Kotanski, J.; Mischler, A.M.

    2009-12-01

    Within the conjectured duality between N=4 super Yang-Mills and Anti-deSitter string theory, the BFKL Pomeron of the gauge theory corresponds to the graviton mode of the dual string. As a first step towards analyzing multigraviton exchange, we investigate R-current six-point functions within the supergravity approximation. We compute the analogue of diffractive scattering, and we analyze the triple Regge limit. In the supergravity approximation the triple graviton vertex is found to vanish. (orig.)

  14. Fermion loops in the effective potential of N = 1 supergravity, with application to no-scale models

    International Nuclear Information System (INIS)

    Burton, J.W.

    1990-01-01

    Powerful and quite general arguments suggest that N = 1 supergravity, and in particular the superstring-inspired no-scale models, may describe the physics of the four-dimensional vacuum at energy densities below the Planck scale. These models are not renormalizable, since they arise as effective theories after the large masses have been integrated out of the fundamental theory; thus, they have divergences in their loop amplitudes that must be regulated by imposing a cutoff. Before physics at experimental energies can be extracted from these models, the true vacuum state or states must be identified: at tree level, the ground states of the effective theories are highly degenerate. Radiative corrections at the one-loop level have been shown to break the degeneracy sufficiently to identify the states of vanishing vacuum energy. As the concluding step in a program to calculate these corrections within a self-consistent cutoff prescription, all fermionic one-loop divergent corrections to the scalar effective potential are evaluated. (The corresponding bosonic contributions have been found elsewhere.) The total effective scalar Lagrange density for N = 1 supergravity is written down, and comments are made about cancellations between the fermionic and bosonic loops. Finally, the result is specialized to a toy no-scale model with a single generation of matter fields, and prospects for eventual phenomenological constraints on theories of this type are briefly discussed. 48 refs

  15. Tanshinone IIA protects against pulmonary arterial hypertension in broilers.

    Science.gov (United States)

    Hu, Guoliang; Song, Yalu; Ke, Shanlin; Cao, Huabin; Zhang, Caiying; Deng, Guangfu; Yang, Fei; Zhou, Sihui; Liu, Pei; Guo, Xiaoquan; Liu, Ping

    2017-05-01

    This investigation was conducted to study the effects of tanshinone IIA (TIIA) on pulmonary arterial hypertension (PAH) in broilers. Two-hundred newly hatched Arbor Acre commercial broilers were randomly divided into 3 groups. All groups, with the exception of the control group (tap water), were given NaCl water (0.3%) starting on the d 15, and broilers in the protected group were fed a diet supplemented with TIIA (2.5 g/kg) starting on the d 15. On d 28, 35, 42, and 49, the ratio of the right ventricular weight to the total ventricular weight (RV: TV) and the values of other biochemical indicators for each group chickens were determined. The concentrations of interleukin-6 (IL-6), interleukin-1β (IL-1β), nuclear factor kappa (NF-κB), and P38 (a mitogen-activated protein kinase) were measured using enzyme-linked immune sorbent assays (ELISA). The results showed that the proportion of chickens in the diseased group with an RV:TV ratio in the range of 0.250 to 0.299 (10%) was significantly higher (25 to 30%) compared to that of the other groups (P chickens was 28%. In addition, the IL-6, IL-1β, NF-κB, and P38 protein concentrations were higher in the diseased group, whereas there were no differences between the control group and the protected group. Moreover, the measurements of body weight, liver function, kidney function and electrolytes showed significant differences between the diseased group and the other groups. These findings suggest that tanshinone IIA may protect broilers from PAH, which is an important piece of information for the poultry industry. © 2016 Poultry Science Association Inc.

  16. Scattering amplitudes in N=2 Maxwell-Einstein and Yang-Mills/Einstein supergravity

    International Nuclear Information System (INIS)

    Chiodaroli, Marco; Günaydin, Murat; Johansson, Henrik; Roiban, Radu

    2015-01-01

    We expose a double-copy structure in the scattering amplitudes of the generic Jordan family of N=2 Maxwell-Einstein and Yang-Mills/Einstein supergravity theories in four and five dimensions. The Maxwell-Einstein supergravity amplitudes are obtained through the color/kinematics duality as a product of two gauge-theory factors; one originating from pure N=2 super-Yang-Mills theory and the other from the dimensional reduction of a bosonic higher-dimensional pure Yang-Mills theory. We identify a specific symplectic frame in four dimensions for which the on-shell fields and amplitudes from the double-copy construction can be identified with the ones obtained from the supergravity Lagrangian and Feynman-rule computations. The Yang-Mills/Einstein supergravity theories are obtained by gauging a compact subgroup of the isometry group of their Maxwell-Einstein counterparts. For the generic Jordan family this process is identified with the introduction of cubic scalar couplings on the bosonic gauge-theory side, which through the double copy are responsible for the non-abelian vector interactions in the supergravity theory. As a demonstration of the power of this structure, we present explicit computations at tree-level and one loop. The double-copy construction allows us to obtain compact expressions for the supergravity superamplitudes, which are naturally organized as polynomials in the gauge coupling constant.

  17. A densitometric analysis of IIaO film flown aboard the space shuttle transportation system STS #3, 7, and 8

    Science.gov (United States)

    Hammond, Ernest C., Jr.

    1989-01-01

    Since the United States of America is moving into an age of reusable space vehicles, both electronic and photographic materials will continue to be an integral part of the recording techniques available. Film as a scientifically viable recording technique in astronomy is well documented. There is a real need to expose various types of films to the Shuttle environment. Thus, the main objective was to look at the subtle densitometric changes of canisters of IIaO film that was placed aboard the Space Shuttle 3 (STS-3).

  18. Retrospective case-control study of surgical treatment of stage IB-IIA cervical carcinomas after neoadjuvant radiotherapy

    International Nuclear Information System (INIS)

    Cigriejiene, V. M.; Kajenas, S.; Balnys, M.; Mikuckaite, L.

    2004-01-01

    To evaluate if preoperative radiotherapy influences course of operation (radical hysterectomy and lymphadenectomy) and postoperative period in series of stage IB-IIA cervical carcinomas. Retrospective comparative study was performed. During the study we analyzed 101 case histories of patients who underwent radical type II hysterectomy with lymphadenectomy in Kaunas University of Medicine Hospital and Kaunas Hospital of Oncology between 1995 and 2002. Mean operation time was shorter, hemoglobin and hematocrit values after operation were better, stay in hospital was longer, demand for narcotic analgetics was bigger, function of ovaries was maintained more rarely (p 0.05). In our study, preoperative radiotherapy did not seem to complicate course of radical hysterectomy. (author)

  19. Value of urinary topoisomerase-IIA cell-free DNA for diagnosis of bladder cancer.

    Science.gov (United States)

    Kim, Ye-Hwan; Yan, Chunri; Lee, Il-Seok; Piao, Xuan-Mei; Byun, Young Joon; Jeong, Pildu; Kim, Won Tae; Yun, Seok-Joong; Kim, Wun-Jae

    2016-03-01

    Topoisomerase-II alpha (TopoIIA ), a DNA gyrase isoform that plays an important role in the cell cycle, is present in normal tissues and various human cancers, and can show altered expression in both. The aim of the current study was to examine the value of urinary TopoIIA cell-free DNA as a noninvasive diagnosis of bladder cancer (BC). Two patient cohorts were examined. Cohort 1 (73 BC patients and seven controls) provided bladder tissue samples, whereas cohort 2 (83 BC patients, 54 nonmalignant hematuric patients, and 61 normal controls) provided urine samples. Real-time quantitative polymerase chain reaction was used to measure expression of TopoIIA mRNA in tissues and TopoIIA cell-free DNA in urine samples. The results showed that expression of TopoIIA mRNA in BC tissues was significantly higher than that in noncancer control tissues (pbladder cancer (MIBC) when compared with nonmuscle invasive bladder cancer (NMIBC) (p=0.002). Receiver operating characteristics (ROC) curve analysis was performed to examine the sensitivity/specificity of urinary TopoIIA cell-free DNA for diagnosing BC, NMIBC, and MIBC. The areas under the ROC curve for BC, NMIBC, and MIBC were 0.741, 0.701, and 0.838, respectively. In summary, the results of this study provide evidence that cell-free TopoIIA DNA may be a potential biomarker for BC.

  20. On the gauged Kaehler isometry in minimal supergravity models of inflation

    International Nuclear Information System (INIS)

    Ferrara, S.; Fre, P.; Sorin, A.S.

    2014-01-01

    In this paper we address the question how to discriminate whether the gauged isometry group G Σ of the Kaehler manifold Σ that produces a D-type inflaton potential in a Minimal Supergravity Model is elliptic, hyperbolic or parabolic. We show that the classification of isometries of symmetric cosets can be extended to non symmetric Σ.s if these manifolds satisfy additional mathematical restrictions. The classification criteria established in the mathematical literature are coherent with simple criteria formulated in terms of the asymptotic behavior of the Kaehler potential K(C) = 2 J(C) where the real scalar field C encodes the inflaton field. As a by product of our analysis we show that phenomenologically admissible potentials for the description of inflation and in particular α-attractors are mostly obtained from the gauging of a parabolic isometry, this being, in particular the case of the Starobinsky model. Yet at least one exception exists of an elliptic α-attractor, so that neither type of isometry can be a priori excluded. The requirement of regularity of the manifold Σ poses instead strong constraints on the α-attractors and reduces their space considerably. Curiously there is a unique integrable α-attractor corresponding to a particular value of this parameter. (Copyright copyright 2014 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  1. Overexpressed human metallothionein IIA gene protects Chinese hamster ovary cells from killing by alkylating agents.

    OpenAIRE

    Kaina, B; Lohrer, H; Karin, M; Herrlich, P

    1990-01-01

    Experiments were designed to detect survival advantages that cells gain by overexpressing metallothionein (MT). Chinese hamster ovary K1-2 cells and an x-ray-sensitive derivative were transfected with a bovine papillomavirus (BPV)-linked construct carrying the human metallothionein IIA (hMT-IIA) gene. Transfectants survived 40-fold higher levels of cadmium chloride, harbored at least 30 copies of hMT-IIA, and contained 25- to 166-fold more MT than the parent cells. Even under conditions of re...

  2. Aspects of AdS, CFT. Black solutions in gauged supergravity and holographic conductivities

    International Nuclear Information System (INIS)

    Barisch-Dick, Susanne

    2013-01-01

    We have met some interesting results within the wide subject of the AdS/CFT correspondence. We have seen how to apply AdS/CFT techniques to calculate the frequency dependent conductivity tensor for field theories dual to a black hole in Einstein-Yang-Mills theory with SU(2) gauge group. Further, we have constructed several new black solutions in N=2 U(1) gauged supergravity in four and five dimensions. The larger part of these solutions behave asymptotically like AdS which makes them interesting within the AdS/CFT context. In addition we found extremal black branes with zero entropy density - the Nernst branes. Nonetheless we are left with some yet unsolved problems. It is very interesting to see what causes the negative entropy production rate we found in chapter 4 for the normal state of the field theory. The next task is to see whether we can find an instability on the gravity side looking at the full Einstein-Yang-Mills equations. Also our work on supergravity solutions in four and five dimension exhibits some ''loose ends''. Since all our four-dimensional Nernst solutions were axion-free it would be nice to find one with axions excited. Moreover, it would be interesting to see whether the singular solutions with flowing γ could be cured by taking into account higher derivative corrections or whether there exist non-singular solutions with non-constant γ. In five dimensions we met problems when adding electric charge. At present we could not find a dyonic solution and we had the impression that having electric charges and having magnetic fields seemed to be somehow complementary to each other. We saw these difficulties even at the beginning when we performed the first-order rewriting since the first-order rewriting in chapter 6 leads to flow equations for the scalars X A which only contain magnetic fields and fluxes but no electric charges. The latter only influence the equations of motion for the X A in an indirect way. However it is possible to find

  3. Class IIa bacteriocin resistance in Enterococcus faecalis V583: The mannose PTS operon mediates global transcriptional responses

    Directory of Open Access Journals (Sweden)

    Opsata Mona

    2010-08-01

    Full Text Available Abstract Background The class IIa bacteriocin, pediocin PA-1, has clear potential as food preservative and in the medical field to be used against Gram negative pathogen species as Enterococcus faecalis and Listeria monocytogenes. Resistance towards class IIa bacteriocins appear in laboratory and characterization of these phenotypes is important for their application. To gain insight into bacteriocin resistance we studied mutants of E. faecalis V583 resistant to pediocin PA-1 by use of transcriptomic analyses. Results Mutants of E. faecalis V583 resistant to pediocin PA-1 were isolated, and their gene expression profiles were analyzed and compared to the wild type using whole-genome microarray. Significantly altered transcription was detected from about 200 genes; most of them encoding proteins involved in energy metabolism and transport. Glycolytic genes were down-regulated in the mutants, but most of the genes showing differential expression were up-regulated. The data indicate that the mutants were relieved from glucose repression and putative catabolic responsive elements (cre could be identified in the upstream regions of 70% of the differentially expressed genes. Bacteriocin resistance was caused by reduced expression of the mpt operon encoding the mannose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS, and the same transcriptional changes were seen in a mptD-inactivated mutant. This mutant also had decreased transcription of the whole mpt operon, showing that the PTS is involved in its own transcriptional regulation. Conclusion Our data confirm the important role of mannose PTS in class IIa bacteriocin sensitivity and we demonstrate its importance involving global carbon catabolite control.

  4. On the Gauged Kahler Isometry in Minimal Supergravity Models of Inflation

    CERN Document Server

    Ferrara, Sergio; Sorin, Alexander S.

    2014-01-01

    In this paper we address the question how to discriminate whether the gauged isometry group G_Sigma of the Kahler manifold Sigma that produces a D-type inflaton potential in a Minimal Supergravity Model is elliptic, hyperbolic or parabolic. We show that the classification of isometries of symmetric cosets can be extended to non symmetric Sigma.s if these manifolds satisfy additional mathematical restrictions. The classification criteria established in the mathematical literature are coherent with simple criteria formulated in terms of the asymptotic behavior of the Kahler potential K(C) = 2 J(C) where the real scalar field C encodes the inflaton field. As a by product of our analysis we show that all phenomenologically admissible potentials for the description of inflation and in particular alpha-attractors are mostly obtained from the gauging of a parabolic isometry. The requirement of regularity of the manifold Sigma poses strong constraints on the alpha-attractors and reduces their space considerably. Curi...

  5. Starobinsky-Like Inflation and Running Vacuum in the Context of Supergravity

    Directory of Open Access Journals (Sweden)

    Spyros Basilakos

    2016-07-01

    Full Text Available We describe the primeval inflationary phase of the early Universe within a quantum field theoretical (QFT framework that can be viewed as the effective action of vacuum decay in the early times. Interestingly enough, the model accounts for the “graceful exit” of the inflationary phase into the standard radiation regime. The underlying QFT framework considered here is supergravity (SUGRA, more specifically an existing formulation in which the Starobinsky-type inflation (de Sitter background emerges from the quantum corrections to the effective action after integrating out the gravitino fields in their (dynamically induced massive phase. We also demonstrate that the structure of the effective action in this model is consistent with the generic idea of re-normalization group (RG running of the cosmological parameters; specifically, it follows from the corresponding RG equation for the vacuum energy density as a function of the Hubble rate, ρ Λ ( H . Overall, our combined approach amounts to a concrete-model realization of inflation triggered by vacuum decay in a fundamental physics context, which, as it turns out, can also be extended for the remaining epochs of the cosmological evolution until the current dark energy era.

  6. The DBI action, higher-derivative supergravity, and flattening inflaton potentials

    International Nuclear Information System (INIS)

    Bielleman, Sjoerd; Ibáñez, Luis E.; Pedro, Francisco G.; Valenzuela, Irene; Wieck, Clemens

    2016-01-01

    In string theory compactifications it is common to find an effective Lagrangian for the scalar fields with a non-canonical kinetic term. We study the effective action of the scalar position moduli of Type II Dp-branes. In many instances the kinetic terms are in fact modified by a term proportional to the scalar potential itself. This can be linked to the appearance of higher-dimensional supersymmetric operators correcting the Kähler potential. We identify the supersymmetric dimension-eight operators describing the α"′ corrections captured by the D-brane Dirac-Born-Infeld action. Our analysis then allows an embedding of the D-brane moduli effective action into an N=1 supergravity formulation. The effects of the potential-dependent kinetic terms may be very important if one of the scalars is the inflaton, since they lead to a flattening of the scalar potential. We analyze this flattening effect in detail and compute its impact on the CMB observables for single-field inflation with monomial potentials.

  7. Topical tofacitinib for atopic dermatitis: a phase IIa randomized trial.

    Science.gov (United States)

    Bissonnette, R; Papp, K A; Poulin, Y; Gooderham, M; Raman, M; Mallbris, L; Wang, C; Purohit, V; Mamolo, C; Papacharalambous, J; Ports, W C

    2016-11-01

    Despite unmet need, 15 years have passed since a topical therapy with a new mechanism of action for atopic dermatitis (AD) has been approved. Janus kinase (JAK) inhibitor treatment effect via topical application in patients with AD is unknown. Tofacitinib, a small-molecule JAK inhibitor, was investigated for the topical treatment of AD. In this 4-week, phase IIa, randomized, double-blind, vehicle-controlled study (NCT02001181), 69 adults with mild-to-moderate AD were randomized 1:1 to 2% tofacitinib or vehicle ointment twice daily. Percentage change from baseline (CFB) in Eczema Area and Severity Index (EASI) score at week 4 was the primary end point. Secondary efficacy end points included percentage CFB in body surface area (BSA), CFB in EASI Clinical Signs Severity Sum Score, proportion of patients with Physician's Global Assessment (PGA) response and CFB in patient-reported pruritus. Safety, local tolerability and pharmacokinetics were monitored. The mean percentage CFB at week 4 in EASI score was significantly greater (P tofacitinib (-81·7%) vs. vehicle (-29·9%). Patients treated with tofacitinib showed significant (P tofacitinib. Tofacitinib ointment showed significantly greater efficacy vs. vehicle across end points, with early onset of effect and comparable safety/local tolerability to vehicle. JAK inhibition through topical delivery is potentially a promising therapeutic target for AD. © 2016 The Authors. British Journal of Dermatology published by John Wiley & Sons Ltd on behalf of British Association of Dermatologists.

  8. New phenomena in the standard no-scale supergravity model

    CERN Document Server

    Kelley, S; Nanopoulos, Dimitri V; Zichichi, Antonino; Kelley, S; Lopez, J L; Nanopoulos, D V; Zichichi, A

    1994-01-01

    We revisit the no-scale mechanism in the context of the simplest no-scale supergravity extension of the Standard Model. This model has the usual five-dimensional parameter space plus an additional parameter \\xi_{3/2}\\equiv m_{3/2}/m_{1/2}. We show how predictions of the model may be extracted over the whole parameter space. A necessary condition for the potential to be stable is {\\rm Str}{\\cal M}^4>0, which is satisfied if \\bf m_{3/2}\\lsim2 m_{\\tilde q}. Order of magnitude calculations reveal a no-lose theorem guaranteeing interesting and potentially observable new phenomena in the neutral scalar sector of the theory which would constitute a ``smoking gun'' of the no-scale mechanism. This new phenomenology is model-independent and divides into three scenarios, depending on the ratio of the weak scale to the vev at the minimum of the no-scale direction. We also calculate the residual vacuum energy at the unification scale (C_0\\, m^4_{3/2}), and find that in typical models one must require C_0>10. Such constrai...

  9. Generalized Killing-Yano equations in D=5 gauged supergravity

    International Nuclear Information System (INIS)

    Kubiznak, David; Kunduri, Hari K.; Yasui, Yukinori

    2009-01-01

    We propose a generalization of the (conformal) Killing-Yano equations relevant to D=5 minimal gauged supergravity. The generalization stems from the fact that the dual of the Maxwell flux, the 3-form *F, couples naturally to particles in the background as a 'torsion'. Killing-Yano tensors in the presence of torsion preserve most of the properties of the standard Killing-Yano tensors - exploited recently for the higher-dimensional rotating black holes of vacuum gravity with cosmological constant. In particular, the generalized closed conformal Killing-Yano 2-form gives rise to the tower of generalized closed conformal Killing-Yano tensors of increasing rank which in turn generate the tower of Killing tensors. An example of a generalized Killing-Yano tensor is found for the Chong-Cvetic-Lue-Pope black hole spacetime [Z.W. Chong, M. Cvetic, H. Lu, C.N. Pope, (hep-th/0506029)]. Such a tensor stands behind the separability of the Hamilton-Jacobi, Klein-Gordon, and Dirac equations in this background.

  10. Split Attractor Flow in N=2 Minimally Coupled Supergravity

    CERN Document Server

    Ferrara, Sergio; Orazi, Emanuele

    2011-01-01

    We classify the stability region, marginal stability walls (MS) and split attractor flows for two-center extremal black holes in four-dimensional N=2 supergravity minimally coupled to n vector multiplets. It is found that two-center (continuous) charge orbits, classified by four duality invariants, either support a stability region ending on a MS wall or on an anti-marginal stability (AMS) wall, but not both. Therefore, the scalar manifold never contains both walls. Moreover, the BPS mass of the black hole composite (in its stability region) never vanishes in the scalar manifold. For these reasons, the "bound state transformation walls" phenomenon does not necessarily occur in these theories. The entropy of the flow trees also satisfies an inequality which forbids "entropy enigma" decays in these models. Finally, the non-BPS case, due to the existence of a "fake" superpotential satisfying a triangle inequality, can be treated as well, and it can be shown to exhibit a split attractor flow dynamics which, at le...

  11. The large N limit of superconformal field theories and supergravity

    International Nuclear Information System (INIS)

    Maldacena, J.

    1999-01-01

    We show that the large N limit of certain conformal field theories in various dimensions include in their Hilbert space a sector describing supergravity on the product of Anti-deSitter spacetimes, spheres and other compact manifolds. This is shown by taking some branes in the full M/string theory and then taking a low energy limit where the field theory on the brane decouples from the bulk. We observe that, in this limit, we can still trust the near horizon geometry for large N. The enhanced supersymmetries of the near horizon geometry correspond to the extra supersymmetry generators present in the superconformal group (as opposed to just the super-Poincare group). The close-quote t Hooft limit of 3+1N=4 super-Yang-Mills at the conformal point is shown to contain strings: they are IIB strings. We conjecture that compactifications of M/string theory on various Anti-deSitter spacetimes is dual to various conformal field theories. This leads to a new proposal for a definition of M-theory which could be extended to include five non-compact dimensions. copyright 1999 American Institute of Physics

  12. Towards loop quantum supergravity (LQSG): I. Rarita–Schwinger sector

    International Nuclear Information System (INIS)

    Bodendorfer, N; Thiemann, T; Thurn, A

    2013-01-01

    In our companion papers, we managed to derive a connection formulation of Lorentzian general relativity in D + 1 dimensions with compact gauge group SO(D + 1) such that the connection is Poisson-commuting, which implies that loop quantum gravity quantization methods apply. We also provided the coupling to standard matter. In this paper, we extend our methods to derive a connection formulation of a large class of Lorentzian signature supergravity theories, in particular 11 D SUGRA and 4 D, N = 8 SUGRA, which was in fact the motivation to consider higher dimensions. Starting from a Hamiltonian formulation in the time gauge which yields a Spin(D) theory, a major challenge is to extend the internal gauge group to Spin(D + 1) in the presence of the Rarita–Schwinger field. This is non-trivial because SUSY typically requires the Rarita–Schwinger field to be a Majorana fermion for the Lorentzian Clifford algebra and Majorana representations of the Clifford algebra are not available in the same spacetime dimension for both Lorentzian and Euclidean signatures. We resolve the arising tension and provide a background-independent representation of the non-trivial Dirac antibracket *-algebra for the Majorana field which significantly differs from the analogous construction for Dirac fields already available in the literature. (paper)

  13. Non-geometric five-branes in heterotic supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Sasaki, Shin; Yata, Masaya [Department of Physics, Kitasato University,Sagamihara 252-0373 (Japan); Department of Physics, National University of Singapore,2, Science Drive 3, Singapore 117542 (Singapore)

    2016-11-10

    We study T-duality chains of five-branes in heterotic supergravity where the first order α{sup ′}-corrections are present. By performing the α{sup ′}-corrected T-duality transformations of the heterotic NS5-brane solutions, we obtain the KK5-brane and the exotic 5{sub 2}{sup 2}-brane solutions associated with the symmetric, the neutral and the gauge NS5-branes. We find that the Yang-Mills gauge field in these solutions satisfies the self-duality condition in the three- and two-dimensional transverse spaces to the brane world-volumes. The O(2,2) monodromy structures of the 5{sub 2}{sup 2}-brane solutions are investigated by the α{sup ′}-corrected generalized metric. Our analysis shows that the symmetric 5{sub 2}{sup 2}-brane solution, which satisfies the standard embedding condition, is a T-fold and it exhibits the non-geometric nature. We also find that the neutral 5{sub 2}{sup 2}-brane solution is a T-fold at least at O(α{sup ′}). On the other hand, the gauge 5{sub 2}{sup 2}-brane solution is not a T-fold but show unusual structures of space-time.

  14. N = 1 supercurrents of eleven-dimensional supergravity

    Science.gov (United States)

    Becker, Katrin; Becker, Melanie; Butter, Daniel; Linch, William D.

    2018-05-01

    Eleven-dimensional supergravity can be formulated in superspaces locally of the form X × Y where X is 4D N = 1 conformal superspace and Y is an arbitrary 7-manifold admitting a G 2-structure. The eleven-dimensional 3-form and the stable 3-form on Y define the lowest component of a gauge superfield on X × Y that is chiral as a superfield on X. This chiral field is part of a tensor hierarchy giving rise to a superspace Chern-Simons action and its real field strength defines a lifting of the Hitchin functional on Y to the G 2 superspace X × Y . These terms are those of lowest order in a superspace Noether expansion in seven N = 1 conformal gravitino superfields Ψ. In this paper, we compute the O(Ψ) action to all orders in the remaining fields. The eleven-dimensional origin of the resulting non-linear structures is parameterized by the choice of a complex spinor on Y encoding the off-shell 4D N = 1 subalgebra of the eleven-dimensional super-Poincaré algebra.

  15. Naturalness Reach of the Large Hadron Collider in Minimal Supergravity

    CERN Document Server

    Allanach, B.C.; Parker, Michael Andrew; Webber, B.R.

    2000-01-01

    We re-analyse the prospects of discovering supersymmetry at the LHC, in order to re-express coverage in terms of a fine-tuning parameter and to extend the analysis to scalar masses (m_0) above 2 TeV. We use minimal supergravity (mSUGRA) unification assumptions for the SUSY breaking parameters. Such high values of m_0 have recently been found to have a focus point, leading to relatively low fine-tuning. In addition, improvements in the simulations since the last study mean that this region no longer lacks radiative electroweak symmetry breaking. The best fine tuning reach is found in a mono-leptonic channel, where for mu>0, A_0=0 and tan beta=10 (corresponding to the focus point), all points in mSUGRA with m_0 < 4000 GeV, with a fine tuning measure up to 300 (570) are covered by the search, where the definition of fine-tuning excludes (includes) the contribution from the top Yukawa coupling. Even for arbitrarily high m_0, mSUGRA does not evade detection provided the gaugino mass parameter M_{1/2} < 460 G...

  16. Supersymmetric Yang-Mills and supergravity amplitudes at one loop

    International Nuclear Information System (INIS)

    Hall, Anthony

    2009-01-01

    By applying the known expressions for super Yang-Mills (SYM) and supergravity (SUGRA) tree amplitudes, we write generating functions for the next-to-next-to-maximally helicity violating (NNMHV) box coefficients of SYM as well as the maximally helicity violating, next-to-maximally helicity violating, and NNMHV box coefficients for SUGRA. The all-multiplicity generating functions utilize covariant, on-shell superspace whereby the contribution from arbitrary external states in the supermultiplet can be extracted by Grassmann operators. In support of the relation between dual-Wilson loops and SYM scattering amplitudes at weak coupling, the SYM amplitudes are presented in a manifestly dual superconformal form. We introduce ordered box coefficients for calculating SUGRA quadruple cuts and prove that ordered coefficients generate physical cut amplitudes after summing over permutations of the external legs. The ordered box coefficients are produced by sewing ordered subamplitudes, previously used in applying on-shell recursion relations at tree level. We describe our verification of the results against the literature, and a formula for extracting the contributions from external gluons or gravitons to NNMHV superamplitudes is presented.

  17. 24 +24 real scalar multiplet in four dimensional N =2 conformal supergravity

    Science.gov (United States)

    Hegde, Subramanya; Lodato, Ivano; Sahoo, Bindusar

    2018-03-01

    Starting from the 48 +48 component multiplet of supercurrents for a rigid N =2 tensor multiplet in four spacetime dimensions, we obtain the transformation of the linearized supergravity multiplet which couples to this supercurrent multiplet. At the linearized level, this 48 +48 component supergravity multiplet decouples into the 24 +24 component linearized standard Weyl multiplet and a 24 +24 component irreducible matter multiplet containing a real scalar field. By a consistent application of the supersymmetry algebra with field-dependent structure constants appropriate to N =2 conformal supergravity, we find the full transformation law for this multiplet in a conformal supergravity background. By performing a suitable field redefinition, we find that the multiplet is a generalization of the flat space multiplet, obtained by Howe et al. in Nucl. Phys. B214, 519 (1983), 10.1016/0550-3213(83)90249-3, to a conformal supergravity background. We also present a set of constraints which can be consistently imposed on this multiplet to obtain a restricted minimal 8 +8 off-shell matter multiplet. We also show, as an example, the precise embedding of the tensor multiplet inside this multiplet.

  18. Point of care testing of phospholipase A2 group IIA for serological diagnosis of rheumatoid arthritis

    Science.gov (United States)

    Liu, Nathan J.; Chapman, Robert; Lin, Yiyang; Mmesi, Jonas; Bentham, Andrew; Tyreman, Matthew; Abraham, Sonya; Stevens, Molly M.

    2016-02-01

    Secretory phospholipase A2 group IIA (sPLA2-IIA) was examined as a point of care marker for determining disease activity in rheumatoid (RA) and psoriatic (PsA) arthritis. Serum concentration and activity of sPLA2-IIA were measured using in-house antibodies and a novel point of care lateral flow device assay in patients diagnosed with varying severities of RA (n = 30) and PsA (n = 25) and found to correlate strongly with C-reactive protein (CRP). Levels of all markers were elevated in patients with active RA over those with inactive RA as well as both active and inactive PsA, indicating that sPLA2-IIA can be used as an analogue to CRP for RA diagnosis at point of care.Secretory phospholipase A2 group IIA (sPLA2-IIA) was examined as a point of care marker for determining disease activity in rheumatoid (RA) and psoriatic (PsA) arthritis. Serum concentration and activity of sPLA2-IIA were measured using in-house antibodies and a novel point of care lateral flow device assay in patients diagnosed with varying severities of RA (n = 30) and PsA (n = 25) and found to correlate strongly with C-reactive protein (CRP). Levels of all markers were elevated in patients with active RA over those with inactive RA as well as both active and inactive PsA, indicating that sPLA2-IIA can be used as an analogue to CRP for RA diagnosis at point of care. Electronic supplementary information (ESI) available. See DOI: 10.1039/c5nr08423g

  19. Tanshinon IIA injection accelerates tissue expansion by reducing the formation of the fibrous capsule.

    Science.gov (United States)

    Yu, Qingxiong; Sheng, Lingling; Yang, Mei; Zhu, Ming; Huang, Xiaolu; Li, Qingfeng

    2014-01-01

    The tissue expansion technique has been applied to obtain new skin tissue to repair large defects in clinical practice. The implantation of tissue expander could initiate a host response to foreign body (FBR), which leads to fibrotic encapsulation around the expander and prolongs the period of tissue expansion. Tanshinon IIA (Tan IIA) has been shown to have anti-inflammation and immunoregulation effect. The rat tissue expansion model was used in this study to observe whether Tan IIA injection systematically could inhibit the FBR to reduce fibrous capsule formation and accelerate the process of tissue expansion. Forty-eight rats were randomly divided into the Tan IIA group and control group with 24 rats in each group. The expansion was conducted twice a week to maintain a capsule pressure of 60 mmHg. The expansion volume and expanded area were measured. The expanded tissue in the two groups was harvested, and histological staining was performed; proinflammatory cytokines such as tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and interleukin-1β (IL-1β) and transforming growth factor-β (TGF-β) were examined. The expansion volume and the expanded area in the Tan IIA group were greater than that of the control group. The thickness of the fibrous capsule in the Tan IIA group was reduced with no influence on the normal skin regeneration. Decreased infiltration of macrophages, lower level of TNF-α, IL-6, IL-1β and TGF-β, less proliferating myofibroblasts and enhanced neovascularization were observed in the Tan IIA group. Our findings indicated that the Tan IIA injection reduced the formation of the fibrous capsule and accelerated the process of tissue expansion by inhibiting the FBR.

  20. Tanshinon IIA injection accelerates tissue expansion by reducing the formation of the fibrous capsule.

    Directory of Open Access Journals (Sweden)

    Qingxiong Yu

    Full Text Available The tissue expansion technique has been applied to obtain new skin tissue to repair large defects in clinical practice. The implantation of tissue expander could initiate a host response to foreign body (FBR, which leads to fibrotic encapsulation around the expander and prolongs the period of tissue expansion. Tanshinon IIA (Tan IIA has been shown to have anti-inflammation and immunoregulation effect. The rat tissue expansion model was used in this study to observe whether Tan IIA injection systematically could inhibit the FBR to reduce fibrous capsule formation and accelerate the process of tissue expansion. Forty-eight rats were randomly divided into the Tan IIA group and control group with 24 rats in each group. The expansion was conducted twice a week to maintain a capsule pressure of 60 mmHg. The expansion volume and expanded area were measured. The expanded tissue in the two groups was harvested, and histological staining was performed; proinflammatory cytokines such as tumor necrosis factor-α (TNF-α, interleukin-6 (IL-6 and interleukin-1β (IL-1β and transforming growth factor-β (TGF-β were examined. The expansion volume and the expanded area in the Tan IIA group were greater than that of the control group. The thickness of the fibrous capsule in the Tan IIA group was reduced with no influence on the normal skin regeneration. Decreased infiltration of macrophages, lower level of TNF-α, IL-6, IL-1β and TGF-β, less proliferating myofibroblasts and enhanced neovascularization were observed in the Tan IIA group. Our findings indicated that the Tan IIA injection reduced the formation of the fibrous capsule and accelerated the process of tissue expansion by inhibiting the FBR.