WorldWideScience

Sample records for twofold axis generates

  1. Generation of Supramolecular Chirality around Twofold Rotational or Helical Axes in Crystalline Assemblies of Achiral Components

    Directory of Open Access Journals (Sweden)

    Mikiji Miyata

    2015-10-01

    Full Text Available A multi-point approximation method clarifies supramolecular chirality of twofold rotational or helical assemblies as well as bundles of the one-dimensional (1D assemblies. While one-point approximation of materials claims no chirality generation of such assemblies, multi-point approximations do claim possible generation in the 1D assemblies of bars and plates. Such chirality derives from deformations toward three-axial directions around the helical axes. The chiral columns are bundled in chiral ways through symmetry operations. The preferable right- or left-handed columns are bundled together to yield chiral crystals with right- or left-handedness, respectively, indicating that twofold helix symmetry operations cause chiral crystals composed of achiral components via a three-stepwise and three-directional process.

  2. Axis: Generating Explanations at Scale with Learnersourcing and Machine Learning

    Science.gov (United States)

    Williams, Joseph Jay; Kim, Juho; Rafferty, Anna; Heffernan, Neil; Maldonado, Samuel; Gajos, Krzysztof Z.; Lasecki, Walter S.; Heffernan, Neil

    2016-01-01

    While explanations may help people learn by providing information about why an answer is correct, many problems on online platforms lack high-quality explanations. This paper presents AXIS (Adaptive eXplanation Improvement System), a system for obtaining explanations. AXIS asks learners to generate, revise, and evaluate explanations as they solve…

  3. Twofold symmetries of the pure gravity action

    Science.gov (United States)

    Cheung, Clifford; Remmen, Grant N.

    2017-01-01

    We recast the action of pure gravity into a form that is invariant under a twofold Lorentz symmetry. To derive this representation, we construct a general parameterization of all theories equivalent to the Einstein-Hilbert action up to a local field redefinition and gauge fixing. We then exploit this freedom to eliminate all interactions except those exhibiting two sets of independently contracted Lorentz indices. The resulting action is local, remarkably simple, and naturally expressed in a field basis analogous to the exponential parameterization of the nonlinear sigma model. The space of twofold Lorentz invariant field redefinitions then generates an infinite class of equivalent representations. By construction, all off-shell Feynman diagrams are twofold Lorentz invariant while all on-shell tree amplitudes are automatically twofold gauge invariant. We extend our results to curved spacetime and calculate the analogue of the Einstein equations. While these twofold invariances are hidden in the canonical approach of graviton perturbation theory, they are naturally expected given the double copy relations for scattering amplitudes in gauge theory and gravity.

  4. Evaluation of the optical axis tilt of Zinc oxide films via noncollinear second harmonic generation

    CERN Document Server

    Bovino, Fabio Antonio; Belardini, Alessandro; Sibilia, Concita

    2009-01-01

    We investigated noncollinear second harmonic generation form Zinc oxide films, grown on glass substrates by dual ion beam sputtering technique. At a fixed incidence angle, the generated signal is investigated by scanning the polarization state of both fundamental beams. We show that the map of the generated signal as a function of polarization states of both pump beams, together with the analytical curves, allows to retrieve the orientation of the optical axis and, eventually, its angular tilt, with respect to the surface normal

  5. A Vertical-Axis Off-Grid Squirrel-Cage Induction Generator Wind Power System

    Directory of Open Access Journals (Sweden)

    Peifeng Xu

    2016-10-01

    Full Text Available In order to broaden the limited utilization range of wind power and improve the charging and discharging control performance of the storage battery in traditional small wind power generation systems, a wind power system based on a vertical-axis off-grid induction generator is proposed in this paper. The induction generator not only can run in a wide wind speed range but can also assist the vertical-axis wind turbine to realize self-starting at low wind speed. Combined with the maximum power point tracking method, the slip frequency control strategy is employed to regulate the pulse width modulation (PWM converter to control the output power of the proposed system when the wind speed and load change. The charge and discharge of the storage battery is realized by the segmented current-limiting control strategy by means of an electric power unloader device connected to the DC bus. All these implement a balanced and stable operation of the proposed power generation system. The experimental research on the 5.5 kW prototype system is developed, and the corresponding results verify the correctness and feasibility of the system design and control strategy. Some comparison experiments with a magnetic suspension permanent magnet synchronous generator (PMSG demonstrate the application prospect of the proposed vertical-axis off-grid induction generator wind power system.

  6. Orbital Angular Momentum in Noncollinear Second Harmonic Generation by off-axis vortex beams

    CERN Document Server

    Bovino, Fabio Antonio; Giardina, Maurizio; Sibilia, Concita

    2011-01-01

    We experimentally study the behavior of orbital angular momentum (OAM) of light in a noncollinear second harmonic generation (SHG) process. The experiment is performed by using a type I BBO crystal under phase matching conditions with femtosecond pumping fields at 830 nm. Two specular off-axis vortex beams carrying fractional orbital angular momentum at the fundamental frequency (FF) are used. We analyze the behavior of the OAM of the SH signal when the optical vortex of each input field at the FF is displaced from the beam's axis. We obtain different spatial configurations of the SH field, always carrying the same zero angular momentum.

  7. Twofold Vlidation of NMET Writing Tests

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    <正>This article takes the validation of NMET writing tests as a point of penetration to examine meticulously and fastidiously whether tests of this kind influence on a national basis can test what it is supposed to test.Here,I shall deal with this issue in a twofold manner,viz.face validity and content validity.Moreover,I also aim to produce findings that could help to guide revisions and promote effectiveness of NMET.After the quantifying and categorizing data collected,I eventually came up with four tables to clearly demonstrate the twofold validity of NMET writing tests.

  8. PREDICTION OF POWER GENERATION OF SMALL SCALE VERTICAL AXIS WIND TURBINE USING FUZZY LOGIC

    Directory of Open Access Journals (Sweden)

    Altab Hossain

    2009-01-01

    Full Text Available Renewable energy from the wind turbine has been focused for the alternative source of power generation due to the following advances of the of the wind turbine. Firstly, the wind turbine is highly efficient and eco-friendly. Secondly, the turbine has the ability to response for the changeable power generation based on the wind velocity and structural framework. However, the competitive efficiency of the wind turbine is necessary to successfully alternate the conventional power sources. The most relevant factor which affects the overall efficiency of the wind turbine is the wind velocity and the relative turbine dimensions. Artificial intelligence systems are widely used technology that can learn from examples and are able to deal with non-linear problems. Compared with traditional approach, fuzzy logic approach is more efficient for the representation, manipulation and utilization. Therefore, the primary purpose of this work was to investigate the relationship between wind turbine power generation and wind velocity, and to illustrate how fuzzy expert system might play an important role in prediction of wind turbine power generation. The main purpose of the measurement over the small scaled prototype vertical axis wind turbine for the wind velocity is to predict the performance of full scaled H-type vertical axis wind turbine. Prediction of power generation at the different wind velocities has been tested at the Thermal Laboratory of Faculty of Engineering, Universiti Industri Selangor (UNISEL and results concerning the daily prediction have been obtained.

  9. Direct generation of linearly polarized single photons with a deterministic axis in quantum dots

    Science.gov (United States)

    Wang, Tong; Puchtler, Tim J.; Patra, Saroj K.; Zhu, Tongtong; Ali, Muhammad; Badcock, Tom J.; Ding, Tao; Oliver, Rachel A.; Schulz, Stefan; Taylor, Robert A.

    2017-08-01

    We report the direct generation of linearly polarized single photons with a deterministic polarization axis in self-assembled quantum dots (QDs), achieved by the use of non-polar InGaN without complex device geometry engineering. Here, we present a comprehensive investigation of the polarization properties of these QDs and their origin with statistically significant experimental data and rigorous k·p modeling. The experimental study of 180 individual QDs allows us to compute an average polarization degree of 0.90, with a standard deviation of only 0.08. When coupled with theoretical insights, we show that these QDs are highly insensitive to size differences, shape anisotropies, and material content variations. Furthermore, 91% of the studied QDs exhibit a polarization axis along the crystal [1-100] axis, with the other 9% polarized orthogonal to this direction. These features give non-polar InGaN QDs unique advantages in polarization control over other materials, such as conventional polar nitride, InAs, or CdSe QDs. Hence, the ability to generate single photons with polarization control makes non-polar InGaN QDs highly attractive for quantum cryptography protocols.

  10. Investigating the effect of a targets time-varying doppler generating axis of rotation on isar image distortion

    CSIR Research Space (South Africa)

    Abdul Gaffar, MY

    2007-10-01

    Full Text Available in ISAR imaging mostly under the limited assumption that a targets axis of rotation is constant over the CPI. This paper investigates how the targets time-varying Doppler generating axis of rotation, caused by the complex 3D motion of a target at sea...

  11. Medial Prefrontal Cortex and HPA Axis Roles in Generation of PTSD-Like Symptoms in SPS Model

    Science.gov (United States)

    2011-09-01

    AD_________________ Award Number: W81XWH-08-1-0661 TITLE: Medial Prefrontal Cortex and HPA Axis...August 2011 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER Medial Prefrontal Cortex and HPA Axis Roles In Generation of PTSD-Like Symptoms In SPS Model...emotional regulation (specific aim #3). 15. SUBJECT TERMS PTSD, SPS, anxiety, fear, conditioning, prefrontal cortex , hippocampus, amygdala 16

  12. Cutter Accessibility Map and Its Application for 5-axis Milling Tool-path Generation

    Institute of Scientific and Technical Information of China (English)

    L. L. Li; Y. F. Zhang

    2006-01-01

    In tool-path generation process for 5-axis face milling, the specification of cutter posture is one of the critical issues that contribute to the computation load. In this paper, a quick algorithm is presented to specify the cutter posture at a surface point based on the cutter's accessibility maps (A-maps) at all the sampled points, obtained during cutter selection. Integrated with this quick algorithm, an efficient approach is proposed to generate a set of iso-planar tool-paths for finishing a given surface withmaximum machining efficiency without violating the desirable profile and scallop height tolerance. One example is given to confirm the validity of the quick algorithm for cutter posture and the efficiency of the algorithm for tool-path generation.

  13. Experimental study on hydrodynamic characteristics of vertical-axis floating tidal current energy power generation device

    Science.gov (United States)

    Ma, Yong; Li, Teng-fei; Zhang, Liang; Sheng, Qi-hu; Zhang, Xue-wei; Jiang, Jin

    2016-10-01

    To study the characteristics of attenuation, hydrostatic towage and wave response of the vertical-axis floating tidal current energy power generation device (VAFTCEPGD), a prototype is designed and experiment is carried out in the towing tank. Free decay is conducted to obtain attenuation characteristics of the VAFTCEPGD, and characteristics of mooring forces and motion response, floating condition, especially the lateral displacement of the VAFTCEPGD are obtained from the towing in still water. Tension response of the #1 mooring line and vibration characteristics of the VAFTCEPGD in regular waves as well as in level 4 irregular wave sea state with the current velocity of 0.6 m/s. The results can be reference for theoretical study and engineering applications related to VAFTCEPGD.

  14. Prediction of broadband noise from large horizontal axis wind turbine generators

    Science.gov (United States)

    Grosveld, F. W.

    1984-01-01

    A method is presented for predicting the broadband noise spectra of large horizontal axis wind turbine generators. It includes contributions from such noise sources as the inflow turbulence to the rotor, the interactions between the turbulent boundary layers on the blade surfaces with their trailing edges and the wake due to a blunt trailing edge. The method is partly empirical and is based on acoustic measurements of large wind turbines and airfoil models. The predicted frequency spectra are compared with measured data from several machines including the MOD-OA, the MOD-2, the WTS-4 and the U.S. Wind-power Inc. machine. Also included is a broadband noise prediction for the proposed MOD-5B. The significance of the effects of machine size, power output, trailing edge bluntness and distance to the receiver is illustrated. Good agreement is obtained between the predicted and measured far field noise spectra.

  15. A novel path generation method of onsite 5-axis surface inspection using the dual-cubic NURBS representation

    Science.gov (United States)

    Li, Wen-long; Wang, Gang; Zhang, Gang; Pang, Chang-tao; Yin, Zhou-pin

    2016-09-01

    Onsite surface inspection with a touch probe or a laser scanner is a promising technique for efficiently evaluating surface profile error. The existing work of 5-axis inspection path generation bears a serious drawback, however, as there is a drastic orientation change of the inspection axis. Such a sudden change may exceed the stringent physical limit on the speed and acceleration of the rotary motions of the machine tool. In this paper, we propose a novel path generation method for onsite 5-axis surface inspection. The accessibility cones are defined and used to generate alternative interference-free inspection directions. Then, the control points are optimally calculated to obtain the dual-cubic non-Uniform rational B-splines (NURBS) curves, which respectively determine the path points and the axis vectors in an inspection path. The generated inspection path is smooth and non-interference, which deals with the ‘mutation and shake’ problems and guarantees a stable speed and acceleration of machine tool rotary motions. Its feasibility and validity is verified by the onsite inspection experiments of impeller blade.

  16. Superconductivity with two-fold symmetry in topological superconductor Sr x Bi2Se3

    Science.gov (United States)

    Du, Guan; Li, YuFeng; Schneeloch, J.; Zhong, R. D.; Gu, GenDa; Yang, Huan; Lin, Hai; Wen, Hai-Hu

    2017-03-01

    Topological superconductivity is the quantum condensate of paired electrons with an odd parity of the pairing function. By using a Corbino-shape like electrode configuration, we measure the c-axis resistivity of the recently discovered superconductor Sr x Bi2Se3 with the magnetic field rotating within the basal planes, and find clear evidence of two-fold superconductivity. The Laue diffraction measurements on these samples show that the maximum gap direction is either parallel or perpendicular to the main crystallographic axis. This observation is consistent with the theoretical prediction and strongly suggests that Sr x Bi2Se3 is a topological superconductor.

  17. Fuzzy unit commitment solution - A novel twofold simulated annealing approach

    Energy Technology Data Exchange (ETDEWEB)

    Saber, Ahmed Yousuf; Senjyu, Tomonobu; Yona, Atsushi; Urasaki, Naomitsu [Faculty of Engineering, University of the Ryukyus, 1 Senbaru, Nishihara-cho Nakagami, Okinawa 903-0213 (Japan); Funabashi, Toshihisa [Meidensha Corporation, Riverside Building 36-2, Tokyo 103-8515 (Japan)

    2007-10-15

    The authors propose a twofold simulated annealing (twofold-SA) method for the optimization of fuzzy unit commitment formulation in this paper. In the proposed method, simulated annealing (SA) and fuzzy logic are combined to obtain SA acceptance probabilities from fuzzy membership degrees. Fuzzy load is calculated from error statistics and an initial solution is generated by a priority list method. The initial solution is decomposed into hourly-schedules and each hourly-schedule is modified by decomposed-SA using a bit flipping operator. Fuzzy membership degrees are the selection attributes of the decomposed-SA. A new solution consists of these hourly-schedules of entire scheduling period after repair, as unit-wise constraints may not be fulfilled at the time of an individual hourly-schedule modification. This helps to detect and modify promising schedules of appropriate hours. In coupling-SA, this new solution is accepted for the next iteration if its cost is less than that of current solution. However, a higher cost new solution is accepted with the temperature dependent total cost membership function. Computation time of the proposed method is also improved by the imprecise tolerance of the fuzzy model. Besides, excess units with the system dependent probability distribution help to handle constraints efficiently and imprecise economic load dispatch (ELD) calculations are modified to save the execution time. The proposed method is tested using standard reported data sets. Numerical results show an improvement in solution cost and time compared to the results obtained from other existing methods. (author)

  18. A 225 kW Direct Driven PM Generator Adapted to a Vertical Axis Wind Turbine

    Directory of Open Access Journals (Sweden)

    S. Eriksson

    2011-01-01

    Full Text Available A unique direct driven permanent magnet synchronous generator has been designed and constructed. Results from simulations as well as from the first experimental tests are presented. The generator has been specifically designed to be directly driven by a vertical axis wind turbine and has an unusually low reactance. Generators for wind turbines with full variable speed should maintain a high efficiency for the whole operational regime. Furthermore, for this application, requirements are placed on high generator torque capability for the whole operational regime. These issues are elaborated in the paper and studied through simulations. It is shown that the generator fulfils the expectations. An electrical control can effectively substitute a mechanical pitch control. Furthermore, results from measurements of magnetic flux density in the airgap and no load voltage coincide with simulations. The electromagnetic simulations of the generator are performed by using an electromagnetic model solved in a finite element environment.

  19. Vortex Breakdown Generated by off-axis Bifurcation in a cylinder with rotating covers

    DEFF Research Database (Denmark)

    Bisgaard, Anders; Brøns, Morten; Sørensen, Jens Nørkær

    2006-01-01

    Vortex breakdown of bubble type is studied for the flow in a cylinder with rotating top and bottom covers. For large ratios of the angular velocities of the covers, we observe numerically that the vortex breakdown bubble in the steady regime may occur through the creation of an off-axis vortex ring...

  20. A design of vertical axis wind power generating system combined with Darrieus-Savonius for adaptation of variable wind speed

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Young Taek; Oh, Chul Soo [Kyung Pook National University, Taegu (Korea, Republic of)

    1996-02-01

    This paper presents a design of vertical axis Darrieus wind turbine combined with Savonius for wind-power generating system to be adapted for variable wind speed. The wind turbine consists of two troposkien- and four Savonius-blades. Darrieus turbine is designed with diameter 9.4[m], chord length 380[mm], tip speed ratio 5. Savonius turbine is designed with diameter 1.8[m], height 2[m], tip speed ratio 0.95. The design of turbine is laid for the main data of rated wind speed 10[m/s], turbine speed 101.4[rpm]. The generating power is estimated to maximum power 20[kWh], and this is converted to commercial power line by means of three phase synchronous generator-inverter system. Generating system is designed for operation on VSVF(variable speed variable frequency) condition and constant voltage system. (author). 11 refs., 14 figs.

  1. Long-term field test of solar PV power generation using one-axis 3-position sun tracker

    KAUST Repository

    Huang, B.J.

    2011-09-01

    The 1 axis-3 position (1A-3P) sun tracking PV was built and tested to measure the daily and long-term power generation of the solar PV system. A comparative test using a fixed PV and a 1A-3P tracking PV was carried out with two identical stand-alone solar-powered LED lighting systems. The field test in the particular days shows that the 1A-3P tracking PV can generate 35.8% more electricity than the fixed PV in a partly-cloudy weather with daily-total solar irradiation HT=11.7MJ/m2day, or 35.6% in clear weather with HT=18.5MJ/m2day. This indicates that the present 1A-3P tracking PV can perform very close to a dual-axis continuous tracking PV (Kacira et al., 2004). The long-term outdoor test results have shown that the increase of daily power generation of 1A-3P tracking PV increases with increasing daily-total solar irradiation. The increase of monthly-total power generation for 1A-3P sun tracking PV is between 18.5-28.0%. The total power generation increase in the test period from March 1, 2010 to March 31, 2011, is 23.6% in Taipei (an area of low solar energy resource). The long-term performance of the present 1X-3P tracking PV is shown very close to the 1-axis continuous tracking PV in Taiwan (Chang, 2009). If the 1A-3P tracking PV is used in the area of high solar energy resource with yearly-average HT>17MJ/m2day, the increase of total long-term power generation with respect to fixed PV will be higher than 37.5%. This is very close to that of dual-axis continuous tracking PV. The 1A-3P tracker can be easily mounted on the wall of a building. The cost of the whole tracker is about the same as the regular mounting cost of a conventional rooftop PV system. This means that there is no extra cost for 1A-3P PV mounted on buildings. The 1A-3P PV is quite suitable for building-integrated applications. © 2011 Elsevier Ltd.

  2. Diabetic Autonomic Neuropathy Affects Symptom Generation and Brain-Gut Axis

    DEFF Research Database (Denmark)

    Brock, Christina; Søfteland, Eirik; Gunterberg, Veronica

    2013-01-01

    OBJECTIVELong-term diabetes leads to severe peripheral, autonomous, and central neuropathy in combination with clinical gastrointestinal symptoms. The brain-gut axis thus expresses a neurophysiological profile, and heart rate variability (HRV) can be correlated with clinical gastrointestinal...... symptoms.RESEARCH DESIGN AND METHODSFifteen healthy volunteers and 15 diabetic patients (12 with type 1 diabetes) with severe gastrointestinal symptoms and clinical suspicion of autonomic neuropathy were included. Psychophysics and evoked brain potentials were assessed after painful rectosigmoid...... autonomic neuropathy and peripheral nervous degeneration, as well as changes in dipole sources in diabetic patients with gastrointestinal symptoms. The findings may lead to improved treatment modalities targeting pharmacological neuroprotection or neuromodulation....

  3. Response measurements for two building structures excited by noise from a large horizontal axis wind turbine generator

    Science.gov (United States)

    Hubbard, H. H.; Shepherd, K. P.

    1984-01-01

    Window and wall acceleration measurements and interior noise measurements ere made for two different building structures during excitation by noise from the WTS-4 horizontal axis wind turbine generator operating in a normal power generation mode. With turbine noise input pulses resulted in acceleration pulses for the wall and window elements of the two tests buildings. Response spectra suggest that natural vibration modes of the structures are excited. Responses of a house trailer were substantially greater than those for a building of sturdier construction. Peak acceleration values correlate well with similar data for houses excited by flyover noise from commercial and military airplanes and helicopters, and sonic booms from supersonic aircraft. Interior noise spectra have peaks at frequencies corresponding to structural vibration modes and room standing waves; and the levels for particular frequencies and locations can be higher than the outside levels.

  4. Measurement and prediction of broadband noise from large horizontal axis wind turbine generators

    Science.gov (United States)

    Grosveld, F. W.; Shepherd, K. P.; Hubbard, H. H.

    1995-01-01

    A method is presented for predicting the broadband noise spectra of large wind turbine generators. It includes contributions from such noise sources as the inflow turbulence to the rotor, the interactions between the turbulent boundary layers on the blade surfaces with their trailing edges and the wake due to a blunt trailing edge. The method is partly empirical and is based on acoustic measurements of large wind turbines and airfoil models. Spectra are predicted for several large machines including the proposed MOD-5B. Measured data are presented for the MOD-2, the WTS-4, the MOD-OA, and the U.S. Windpower Inc. machines. Good agreement is shown between the predicted and measured far field noise spectra.

  5. Permanent magnet generator for direct drive for vertical axis turbine; Gerador de imas permanentes de acionamento direto para turbina de eixo vertical

    Energy Technology Data Exchange (ETDEWEB)

    Eriksson, Sandra; Semberg, Tobias; Bernhoff, Hans; Leijon, Mats [Universidade de Uppsala (Sweden)

    2011-10-15

    The design and construction of a synchronous generator specifically designed to be directly driven by a vertical axis wind turbine are described here. The generator is unique in many respects: it has several poles, large diameter, relatively high voltage, low speed and high overload capability. Among other important aspects, the article discusses the differences between the simulated geometry and the obtained.

  6. INTERFERENCE-FREE TOOL POSTURE GENERATION FOR 5-AXIS NC MILLING FREE-FORM SURFACES WITH CYLINDRICAL MILL

    Institute of Scientific and Technical Information of China (English)

    Chen Liping; Chen Yan; Hu Dejin

    2004-01-01

    The 5-axis NC machining offers the potential of efficient and accurate machining. However, the present CAM system for 5-axis control is still an unsolved problem due to interference between tool and surrounding objects. A new method is presented. There are two steps in this procedure. First, it detects the interference by calculating the shortest distance between the tool-axis and the surrounding surfaces. Then upon the maximum gouging, the interference-free tool posture for 5-axis NC cylindrical milling free-form surfaces is obtained by adjusting tool. The validity of the proposed method has been confirmed by machining an impeller.

  7. Parametric sensitivity of two axis models for turbo-generators; Sensibilidad parametrica de modelos de dos ejes para turbogeneradores

    Energy Technology Data Exchange (ETDEWEB)

    Morales Castorena, Armando

    2003-06-15

    The results of parameter sensitivity studies performed on two axis equivalent circuits (TAECs) of synchronous machines are presented in this thesis. The circuits consist of inductive and resistive elements. Their connectivity represents the magnetic and electric coupling inside the machine as well as its energy losses. Two equivalent circuits are needed to represent the machine, one for the direct axis (d) and another for the quadrature axis (q), because it is modeled under the two-axis reaction theory of Park. Parameter values have been identified in advance, using standstill frequency response tests (SSFR). This response was calculated using a finite element model of a turbine generator. The parameter identification is achieved by applying an optimization process based on a hybrid algorithm (stochastic-deterministic). The fitness function is defined as the square of the differences between magnitudes and phase angles of the frequency response functions of the TAECs and of the turbogenerator. This procedure yields the TAECs that better fit the frequency response of the machine. Thus, the circuits identified are considered good models of the machine and they can be applied for digital simulation of dynamic behavior. The identified TAECs are the basis of the parameter sensitivity studies reported here. These studies consist of doing very small variations to parameter values, and to calculate the new value of the fitness function. The ratio between the change of the fitness function to the change in parameter value is called sensitivity of the fitness function, or simply, sensitivity function. Its magnitude indicates which parameter has a greater or lesser influence on the fitness function. If the fitness function is very sensitive to a particular parameter, then the rightness of the identified value of that parameter may be in doubt. With this information it is possible to establish the reliability of the identification process and to exert corrective actions. It is

  8. The Performance Evaluation of Horizontal Axis Wind Turbine Torque and Mechanical Power Generation Affected by the Number of Blade

    Directory of Open Access Journals (Sweden)

    Tan Rodney H. G.

    2016-01-01

    Full Text Available This paper presents the evaluation of horizontal axis wind turbine torque and mechanical power generation and its relation to the number of blades at a given wind speed. The relationship of wind turbine rotational frequency, tip speed, minimum wind speed, mechanical power and torque related to the number of blades are derived. The purpose of this study is to determine the wind energy extraction efficiency achieved for every increment of blade number. Effective factor is introduced to interpret the effectiveness of the wind turbine extracting wind energy below and above the minimum wind speed for a given number of blades. Improve factor is introduced to indicate the improvement achieved for every increment of blades. The evaluation was performance with wind turbine from 1 to 6 blades. The evaluation results shows that the higher the number of blades the lower the minimum wind speed to achieve unity effective factor. High improve factors are achieved between 1 to 2 and 2 to 3 blades increment. It contributes to better understanding and determination for the choice of the number of blades for wind turbine design.

  9. Sex is always well worth its two-fold cost.

    Directory of Open Access Journals (Sweden)

    Alexander Feigel

    Full Text Available Sex is considered as an evolutionary paradox, since its positive contribution to Darwinian fitness remains unverified for some species. Defenses against unpredictable threats (parasites, fluctuating environment and deleterious mutations are indeed significantly improved by wider genetic variability and by positive epistasis gained by sexual reproduction. The corresponding evolutionary advantages, however, do not overcome universally the barrier of the two-fold cost for sharing half of one's offspring genome with another member of the population. Here we show that sexual reproduction emerges and is maintained even when its Darwinian fitness is twice as low as the fitness of asexuals. We also show that more than two sexes (inheritance of genetic material from three or even more parents are always evolutionary unstable. Our approach generalizes the evolutionary game theory to analyze species whose members are able to sense the sexual state of their conspecifics and to adapt their own sex consequently, either by switching or by taxis towards the highest concentration of the complementary sex. The widespread emergence and maintenance of sex follows therefore from its co-evolution with the even more widespread environmental sensing abilities.

  10. Twofold Transition in PT-symmetric Coupled Oscillators

    Science.gov (United States)

    2013-12-26

    2Dipartimento di Matematica e Fisica Ennio De Giorgi, Università del Salento and I. N. F. N. Sezione di Lecce, Via Arnesano, I-73100 Lecce, Italy...supermode, as shown in Fig. 6, instead of two pairs of real frequencies. B. Unbalanced loss and gain Let us consider the general case (2) in which μ = ν...correspond to the eigenfunctions ψm,n(x,y). The eigenfunctions have the general form ψm,n(x,y) = e−(2axy+bx2+cy2)/2Pm,n(x,y), (12) where b = c∗ = 2(a

  11. 基于Pro/E的五轴激光切割轨迹生成%5-Axis Laser Cutting Path Generation Based on Pro/E

    Institute of Scientific and Technical Information of China (English)

    朱虎; 扶建辉

    2013-01-01

    To meet the demand of 5-axis laser cutting, a method for generation of 5-axis laser cutting path based on the Pro/E software was discussed. A curve for the generation of laser cutting path with compensating the laser beam radius was created by preprocessing the part.' Then the 5-axis laser cutting path that could guarantee the laser beam perpendicular to the part surface all the time was generated by using the function of "vertical to the part" of the "path milling" style.%为满足五轴激光切割的需要,探讨一种利用Pro/E软件生成五轴激光数控切割轨迹的方法.通过对被切割零件模型进行预处理,生成一个补偿激光束半径的激光切割轨迹生成曲线,然后采用“轨迹铣削”加工方式中的“垂直于零件”功能,生成了能够保证激光束始终垂直于被切割零件表面的五轴激光数控切割轨迹.

  12. A Two-Fold Unveiling: Unmasking Classism in Group Work

    Science.gov (United States)

    Newton, Kathryn

    2010-01-01

    The pervasive myth of the United States as a "classless society" silences the reality of social class oppression in this country. This silencing has received little attention to date in group work training, research, and practice. Unmasking classism may generate anxiety for group workers and members alike, yet holds potential for significant…

  13. Multi-resolutional Medial Axis Generation for Solid Models%实体模型的多分辨率中轴生成

    Institute of Scientific and Technical Information of China (English)

    朱厚盛; 刘玉生

    2015-01-01

    According to the requirement of the dimensionality reduction of solid models, a multi-resolution medial axis generation method is proposed for solid models. According to different model levels, the parts of the model that need to be refined are found out first. Then, the boundary is voxelized with the help of the results. After that, the distances of the multi-resolution voxels are computed by distance dilation method. Finally, the multi-resolution medial axis voxels are computed according to the distances of voxels. Several groups of experiments are given to demonstrate that the multi-resolution medial axis of high quality can be generated with low time and space cost using the proposed method.%针对模型降维的需要,提出一种实体模型的多分辨率中轴生成方法。首先根据模型的层次寻找模型中需要细化的部分,并据此对边界进行体素化;其次使用距离蔓延的方法计算多分辨率体素的距离;最后根据体素的距离计算出多分辨率的中轴体素。实验结果表明,该方法可以以低时间空间代价生成高质量的多分辨率中轴。

  14. Control System of Vertical Axis Aero Wind-Power Generator%垂直轴风力发电测控系统

    Institute of Scientific and Technical Information of China (English)

    廖光荣; 李树广

    2012-01-01

    为立式风力发电系统设计了新型集风立式风机、多绕组变极发电机、异步的数据采集系统、发电机和风速控制系统.新型集风立式风机克服了传统三叶桨风力利用率低、发电功率低、保护性差的特点.利用DSP触发FPGA控制外置两片AD7656可以达到高精度数据采集和高实时数据处理以及控制的并行化.双DSP架构通过双口RAM共享存储,提高了实时通信的吞吐率,同时将实时任务和耗时的显示等人机交互任务分离.一方面在PIC里存储模糊规则表,实现对集风板的模糊控制,进而调节风速;另一方面通过多绕组变极发电机的绕组和励磁方式切换,来保持发电机输出电压频率、幅值和相位的稳定,解决了风电并网的难题.%A new wind-collected vertical-axis wind turbine, multi-winding pole-changing generator, asynchronous data acquisition system, generators and wind speed control system are designed for vertical wind power generation system. The new wind-collected vertical-axis wind turbine overcomes the shortcoming of the traditional horizontal-axis wind turbine with low wind energy utilization, low power generation, vulnerable under fierce wind. Using DSP triggering FPGA to control two AD7656 chips can achieve the parallelism performance of high-precision data acquisition and real-time data processing or control. Dual-DSP architecture can separate the real-time tasks and time-consumed tasks such as display and etc to improve the real-time performance. U-sing fuzzy control rules stored in the PLC to adjust wind speed through the position of wind-collected board and the multi-winding switching can assure the stability of frequency and amplitude and phase of the generator to simplify the wind power to join the power grid.

  15. System Integration of the Horizontal-Axis Wind Turbine: The Design of Turbine Blades with an Axial-Flux Permanent Magnet Generator

    Directory of Open Access Journals (Sweden)

    Chi-Jeng Bai

    2014-11-01

    Full Text Available In designing a horizontal-axis wind turbine (HAWT blade, system integration between the blade design and the performance test of the generator is important. This study shows the aerodynamic design of a HAWT blade operating with an axial-flux permanent magnet (AFPM generator. An experimental platform was built to measure the performance curves of the AFPM generator for the purpose of designing the turbine blade. An in-house simulation code was developed based on the blade element momentum (BEM theory and was used to lay out the geometric shape of the turbine blade, including the pitch angle and chord length at each section. This simulation code was combined with the two-dimensional (2D airfoil data for predicting the aerodynamic performance of the designed blades. In addition, wind tunnel experiments were performed to verify the simulation results for the various operating conditions. By varying the rotational speeds at four wind speeds, the experimental and simulation results for the mechanical torques and powers presented good agreement. The mechanical power of the system, which maximizes at the best operating region, provided significant information for designing the HAWT blade.

  16. A Two-folded Impact Analysis of Schema Changes on Database Applications

    Institute of Scientific and Technical Information of China (English)

    Spyridon K.Gardikiotis; Nicos Malevris

    2009-01-01

    Database applications are becoming increasingly popular, mainly due to the advanced data management facilities that the underlying database management system offers compared against traditional legacy software applications. The interaction, however, of such applications with the database system introduces a number of issues, among which, this paper addresses the impact analysis of the changes performed at the database schema level. Our motivation is to provide the software engineers of database applications with automated methods that facilitate major maintenance tasks, such as source code corrections and regression testing, which should be triggered by the occurrence of such changes. The presented impact analysis is thus two-folded: the impact is analysed in terms of both the affected source code statements and the affected test suites concerning the testing of these applications. To achieve the former objective, a program slicing technique is employed, which is based on an extended version of the program dependency graph. The latter objective requires the analysis of test suites generated for database applications, which is accomplished by employing testing techniques tailored for this type of applications. Utilising both the slicing and the testing techniques enhances program comprehension of database applications, while also supporting the development of a number of practical metrics regarding their maintainability against schema changes. To evaluate the feasibility and effectiveness of the presented techniques and metrics, a software tool, called DATA, has been implemented. The experimental results from its usage on the TPC-C case study are reported and analysed.

  17. CONSERVATION PROCESS MODEL (CPM): A TWOFOLD SCIENTIFIC RESEARCH SCOPE IN THE INFORMATION MODELLING FOR CULTURAL HERITAGE

    National Research Council Canada - National Science Library

    D. Fiorani; M. Acierno

    2017-01-01

    The aim of the present research is to develop an instrument able to adequately support the conservation process by means of a twofold approach, based on both BIM environment and ontology formalisation...

  18. Automated segmentation of the human hippocampus along its longitudinal axis.

    Science.gov (United States)

    Lerma-Usabiaga, Garikoitz; Iglesias, Juan Eugenio; Insausti, Ricardo; Greve, Douglas N; Paz-Alonso, Pedro M

    2016-09-01

    The human hippocampal formation is a crucial brain structure for memory and cognitive function that is closely related to other subcortical and cortical brain regions. Recent neuroimaging studies have revealed differences along the hippocampal longitudinal axis in terms of structure, connectivity, and function, stressing the importance of improving the reliability of the available segmentation methods that are typically used to divide the hippocampus into its anterior and posterior parts. However, current segmentation conventions present two main sources of variability related to manual operations intended to correct in-scanner head position across subjects and the selection of dividing planes along the longitudinal axis. Here, our aim was twofold: (1) to characterize inter- and intra-rater variability associated with these manual operations and compare manual (landmark based) and automatic (percentage based) hippocampal anterior-posterior segmentation procedures; and (2) to propose and test automated rotation methods based on approximating the hippocampal longitudinal axis to a straight line (estimated with principal component analysis, PCA) or a quadratic Bézier curve (fitted with numerical methods); as well as an automated anterior-posterior hippocampal segmentation procedure based on the percentage-based method. Our results reveal that automated rotation and segmentation procedures, used in combination or independently, minimize inconsistencies generated by the accumulation of manual operations while providing higher statistical power to detect well-known effects. A Matlab-based implementation of these procedures is made publicly available to the research community. Hum Brain Mapp 37:3353-3367, 2016. © 2016 Wiley Periodicals, Inc.

  19. Testing the Twofold Multidimensionality of Academic Self-Concept: A Study with Chinese Vocational Students

    Science.gov (United States)

    Yang, Lan; Arens, A. Katrin; Watkins, David A.

    2016-01-01

    In order to extend previous research on the twofold multidimensionality of academic self-concept (i.e. its domain-specific structure and separation into competence and affect components), the present study tests its generalisability among vocational students from mainland China. A Chinese version of self-description questionnaire I was…

  20. The two-fold singularity of nonsmooth flows:Leading order dynamics in n-dimensions

    OpenAIRE

    Colombo, Alessandro; Jeffrey, Mike R.

    2013-01-01

    A discontinuity in a system of ordinary differential equations can create allow that slides along the discontinuity locus. Prior to sliding, the flow may have collapsed onto the discontinuity, making the reverse flow non-unique, as happens when dry-friction causes objects to stick. Alternatively, a flow may slide along the discontinuity before escaping it at some indeterminable time, implying non-uniqueness in forward time. At a two-fold singularity these two behaviours are brought together, ...

  1. Bayesian Predictive Inference of a Proportion Under a Twofold Small-Area Model

    Directory of Open Access Journals (Sweden)

    Nandram Balgobin

    2016-03-01

    Full Text Available We extend the twofold small-area model of Stukel and Rao (1997; 1999 to accommodate binary data. An example is the Third International Mathematics and Science Study (TIMSS, in which pass-fail data for mathematics of students from US schools (clusters are available at the third grade by regions and communities (small areas. We compare the finite population proportions of these small areas. We present a hierarchical Bayesian model in which the firststage binary responses have independent Bernoulli distributions, and each subsequent stage is modeled using a beta distribution, which is parameterized by its mean and a correlation coefficient. This twofold small-area model has an intracluster correlation at the first stage and an intercluster correlation at the second stage. The final-stage mean and all correlations are assumed to be noninformative independent random variables. We show how to infer the finite population proportion of each area. We have applied our models to synthetic TIMSS data to show that the twofold model is preferred over a onefold small-area model that ignores the clustering within areas. We further compare these models using a simulation study, which shows that the intracluster correlation is particularly important.

  2. A female-biased sex ratio reduces the twofold cost of sex

    Science.gov (United States)

    Kobayashi, Kazuya; Hasegawa, Eisuke

    2016-04-01

    The evolution of sexual reproduction remains a fascinating enigma in biology. Theoretically, populations of sexual organisms investing half of their resources into producing male offspring that don’t contribute to reproduction should grow at only half the rate of their asexual counterparts. This demographic disadvantage due to male production is known as the twofold cost of sex. However, the question of whether this cost is truly twofold for sexual females remains unanswered. The cost of producing males should decrease when the number of male offspring is reduced. Here, we report a case where the cost of males is actually less than twofold. By measuring the numbers of sexual strain coexisting with asexual strain among thrips, our survey revealed that the sexual strain showed female-biased sex ratios and that the relative frequency of sexual strain is negatively correlated with the proportion of males in the sexual strain. Using computer simulations, we confirmed that a female-biased sex ratio evolves in sexual individuals due to the coexistence of asexual individuals. Our results demonstrate that there is a cost of producing males that depends on the number of males. We therefore conclude that sexual reproduction can evolve with far fewer benefits than previously assumed.

  3. Developing predictive approaches to characterize adaptive responses of the reproductive endocrine axis to aromatase inhibition: I. Data generation in a small fish model

    Science.gov (United States)

    Adaptive or compensatory responses to chemical exposure can significantly influence in vivo concentration-duration-response relationships. The aim of this study was to provide data to support development of a computational dynamic model of the hypothalamic-pituitary-gonadal axis ...

  4. Vertical axis wind turbines

    Science.gov (United States)

    Krivcov, Vladimir [Miass, RU; Krivospitski, Vladimir [Miass, RU; Maksimov, Vasili [Miass, RU; Halstead, Richard [Rohnert Park, CA; Grahov, Jurij [Miass, RU

    2011-03-08

    A vertical axis wind turbine is described. The wind turbine can include a top ring, a middle ring and a lower ring, wherein a plurality of vertical airfoils are disposed between the rings. For example, three vertical airfoils can be attached between the upper ring and the middle ring. In addition, three more vertical airfoils can be attached between the lower ring and the middle ring. When wind contacts the vertically arranged airfoils the rings begin to spin. By connecting the rings to a center pole which spins an alternator, electricity can be generated from wind.

  5. Soft-wall domain-growth kinetics of twofold-degenerate ordering

    DEFF Research Database (Denmark)

    Mouritsen, Ole G.

    1986-01-01

    The domain growth in a two-dimensional twofold-degenerate system with soft domain walls is shown to obey dynamical scaling. The value of the growth exponent is n≃0.25 which differs from the classical Lifshitz-Allen-Cahn prediction n=(1/2), but accords with recent findings for other growth models ...... with soft walls. The results suggest that domain-wall softness may be more important than the degeneracy of the ground state for a possible universal classification of domain-growth kinetics....

  6. Thermodynamics of chemical free energy generation in off-axis hydrothermal vent systems and its consequences for compartmentalization and the emergence of life

    CERN Document Server

    Simoncini, E; Gallori, E; .,

    2010-01-01

    In this paper we demonstrate how chemical free energy can be produced by a geological process. We provide a thermodynamic framework in which to assess how life emerged at the off-axis hydrothermal vent system; the RNA - clays system has been investigated from the entropic point of view, showing that the stabilization of the system in a state further away from equilibrium state, by an inorganic heterogeneous compartmetalization phenomena, is able to produce chemical free energy useful for RNA self - replication.

  7. Two-fold Mellin–Barnes transforms of Usyukina–Davydychev functions

    Energy Technology Data Exchange (ETDEWEB)

    Kniehl, Bernd A., E-mail: kniehl@desy.de [II. Institut für Theoretische Physik, Universität Hamburg, Luruper Chaussee 149, 22761 Hamburg (Germany); Kondrashuk, Igor [Grupo de Matemática Aplicada, Departamento de Ciencias Básicas, Universidad del Bío-Bío, Campus Fernando May, Casilla 447, Chillán (Chile); Fakultät für Physik, Universität Bielefeld, Universitätsstraße 25, 33615 Bielefeld (Germany); Notte-Cuello, Eduardo A. [Departamento de Matemáticas, Facultad de Ciencias, Universidad de La Serena, Av. Cisternas 1200, La Serena (Chile); Parra-Ferrada, Ivan [Carrera de Pedagogia en Matemática, Facultad de Educación y Humanidades, Universidad del Bío-Bío, Campus Castilla, Casilla 447, Chillán (Chile); Rojas-Medar, Marko [Grupo de Matemática Aplicada, Departamento de Ciencias Básicas, Universidad del Bío-Bío, Campus Fernando May, Casilla 447, Chillán (Chile)

    2013-11-01

    In our previous paper (Allendes et al., 2013 [10]), we showed that multi-fold Mellin–Barnes (MB) transforms of Usyukina–Davydychev (UD) functions may be reduced to two-fold MB transforms. The MB transforms were written there as polynomials of logarithms of ratios of squares of the external momenta with certain coefficients. We also showed that these coefficients have a combinatoric origin. In this paper, we present an explicit formula for these coefficients. The procedure of recovering the coefficients is based on taking the double-uniform limit in certain series of smooth functions of two variables which is constructed according to a pre-determined iterative way. The result is obtained by using basic methods of mathematical analysis. We observe that the finiteness of the limit of this iterative chain of smooth functions should reflect itself in other mathematical constructions, too, since it is not related in any way to the explicit form of the MB transforms. This finite double-uniform limit is represented in terms of a differential operator with respect to an auxiliary parameter which acts on the integrand of a certain two-fold MB integral. To demonstrate that our result is compatible with original representations of UD functions, we reproduce the integrands of these original integral representations by applying this differential operator to the integrand of the simple integral representation of the scalar triangle four-dimensional integral J(1,1,1−ε)

  8. An Efficient Two-Fold Marginalized Bayesian Filter for Multipath Estimation in Satellite Navigation Receivers

    Directory of Open Access Journals (Sweden)

    Robertson Patrick

    2010-01-01

    Full Text Available Multipath is today still one of the most critical problems in satellite navigation, in particular in urban environments, where the received navigation signals can be affected by blockage, shadowing, and multipath reception. Latest multipath mitigation algorithms are based on the concept of sequential Bayesian estimation and improve the receiver performance by exploiting the temporal constraints of the channel dynamics. In this paper, we specifically address the problem of estimating and adjusting the number of multipath replicas that is considered by the receiver algorithm. An efficient implementation via a two-fold marginalized Bayesian filter is presented, in which a particle filter, grid-based filters, and Kalman filters are suitably combined in order to mitigate the multipath channel by efficiently estimating its time-variant parameters in a track-before-detect fashion. Results based on an experimentally derived set of channel data corresponding to a typical urban propagation environment are used to confirm the benefit of our novel approach.

  9. Magnetocrystalline two-fold symmetry in CaFe2O4 single crystal

    Science.gov (United States)

    Chhaganlal Gandhi, Ashish; Das, Rajasree; Chou, Fang-Cheng; Lin, Jauyn Grace

    2017-05-01

    Understanding of magnetocrystalline anisotropy in CaFe2O4 is a matter of importance for its future applications. A high quality single crystal CaFe2O4 sample is studied by using synchrotron x-ray diffraction, a magnetometer and the electron spin resonance (ESR) technique. A broad feature of the susceptibility curve around room temperature is observed, indicating the development of 1D spin interactions above the on-set of antiferromagnetic transition. The angular dependency of ESR reveals an in-plane two-fold symmetry, suggesting a strong correlation between the room temperature spin structure and magnetocrystalline anisotropy. This finding opens an opportunity for the device utilizing the anisotropy field of CaFe2O4.

  10. Complete controllability of finite quantum systems with twofold energy level degeneracy

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Zhedong; Fu, H C, E-mail: hcfu@szu.edu.c [School of Physical Sciences and Technology, Shenzhen University, Shenzhen 518060 (China)

    2010-05-28

    Complete controllability of finite-dimensional quantum systems with energy level degeneracy is investigated using two different approaches. One approach is to apply a weak constant field to eliminate the degeneracy and then control it using techniques developed for non-degenerate quantum systems. Conditions for the elimination of degeneracy are found and the issues of influence of relaxation time of a constant external field on the target state are addressed through the fidelity. Another approach is to control the degenerate system by a single control field directly. It is found that the system with twofold degenerate excited states and non-degenerate ground state is completely controllable except for the two-level system. Conditions of complete controllability are found for both systems with different energy gaps and with equal energy gaps.

  11. An unusual binodal (6,8)-connected 3D supramolecular network with twofold self-penetration

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    A dicarboxylate ligand,5-carboxyl-1-carboxymethyl-2-oxidopyridinium (H2L),was utilized to form four complexes with the general formula [M(HL)2(H2O)]·2H2O,M = CuII (1),ZnII (2),MnII (3),CdII (4).The crystals were isomorphous,belonging to the monoclinic C2/c space group.They were constructed from 1D chains and further linked by hydrogen bonds into a novel binodal (6,8)-connected 3D supramolecular network with twofold self-penetration.Photoluminescence studies revealed that complexes 2-4 displayed intense structure-related fluorescent emission bands.

  12. Mean flow generation in rotating anelastic two-dimensional convection

    CERN Document Server

    Currie, Laura K

    2016-01-01

    We investigate the processes that lead to the generation of mean flows in two-dimensional anelastic convection. The simple model consists of a plane layer that is rotating about an axis inclined to gravity. The results are two-fold: firstly we numerically investigate the onset of convection in three-dimensions, paying particular attention to the role of stratification and highlight a curious symmetry. Secondly, we investigate the mechanisms that drive both zonal and meridional flows in two dimensions. We find that, in general, non-trivial Reynolds stresses can lead to systematic flows and, using statistical measures, we quantify the role of stratification in modifying the coherence of these flows.

  13. Principles of the prolactin/vasoinhibin axis.

    Science.gov (United States)

    Triebel, Jakob; Bertsch, Thomas; Bollheimer, Cornelius; Rios-Barrera, Daniel; Pearce, Christy F; Hüfner, Michael; Martínez de la Escalera, Gonzalo; Clapp, Carmen

    2015-11-15

    The hormonal family of vasoinhibins, which derive from the anterior pituitary hormone prolactin, are known for their inhibiting effects on blood vessel growth, vasopermeability, and vasodilation. As pleiotropic hormones, vasoinhibins act in multiple target organs and tissues. The generation, secretion, and regulation of vasoinhibins are embedded into the organizational principle of an axis, which integrates the hypothalamus, the pituitary, and the target tissue microenvironment. This axis is designated as the prolactin/vasoinhibin axis. Disturbances of the prolactin/vasoinhibin axis are associated with the pathogenesis of retinal and cardiac diseases and with diseases occurring during pregnancy. New phylogenetical, physiological, and clinical implications are discussed.

  14. Study on wave power generation of electricity using torsion arc blade type horizontal axis wind turbine; Nejire enko yokugata suihei jiku fusha wo mochiita haryoku hatsuden ni kansuru kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    Kojima, N.; Kishimura, K. [Meiji University, Tokyo (Japan)

    1996-10-27

    Windmilling characteristics of a combination of a torsion arc blade type (TABT) horizontal axis wind turbine and a reverse torsion arc blade type (RTABT) horizontal axis wind turbine were evaluated in a wave activated power generation experiment. The TABT wind turbine had six blades, and the front and rear parts of the blade were twisted in the same direction, which caused the direction of rotor rotation to change as the direction of wind along the shaft changed. The RTABT wind turbine had twelve blades, and the front and rear parts of the blade were twisted reverse to each other, which allowed the direction of rotor rotation to stay constant even in the presence of wind direction reversal. To keep the direction of rotor rotation unchanged in the presence of flow direction reversal along the power generating turbine shaft, a single-stage type RTABT wind turbine and a double-stage type were used, the double-stage type being a series connection of a first-stage RTABT (for blowout and suction) and second-stage TABT (for blowout only). Both single-type and double-type rotated in the same direction irrespective of the direction of air flow. The output of the double type was obtained by adding up the values obtained from the individual turbines. The double type was two to three times higher in efficiency than the single type in turbine revolution and power output. 2 refs., 13 figs.

  15. Multigenerational effects of fetal dexamethasone exposure on the hypothalamic-pituitary-adrenal axis of first- and second-generation female offspring.

    Science.gov (United States)

    Long, Nathan M; Ford, Stephen P; Nathanielsz, Peter W

    2013-03-01

    Synthetic glucocorticoid (sGC) administration to women threatening preterm delivery increases neonatal survival. Evidence shows that fetal exposure to glucocorticoid levels higher than appropriate for current maturation programs offspring development. We examined fetal sGC multigenerational effects on F1 and F2 female offspring hypothalamo-pituitary-adrenal axis (HPAA) function. At 0.7 gestation, pregnant F0 ewes received 4 dexamethasone injections (2 mg, approximately 60 μg/kg(-1) per day(-1), 12 hours apart) or saline (control). F1 female offspring were bred to produce F2 female offspring. Postpubertal HPAA function was tested in F1 and F2 ewes. F1 and F2 ewe lambs showed reduced birthweight and morphometrics. Dexamethasone increased baseline but reduced stimulated HPAA activity in F1 and F2 female offspring. This is the first demonstration that sGC doses in the clinical range have multigenerational effects on hypothalamo-pituitary-adrenal activity in a precocial species, indicating the need for the study of long-term effects of fetal sGC exposure. Copyright © 2013 Mosby, Inc. All rights reserved.

  16. Two-fold Mellin-Barnes transforms of Usyukina-Davydychev functions

    CERN Document Server

    Kniehl, Bernd; Notte-Cuello, Eduardo A; Ferrada, Ivan Parra; Rojas-Medar, Marko

    2013-01-01

    In our previous paper (Nucl.Phys.B 870 (2013) 243) we showed that multi-fold Mellin-Barnes (MB) transforms of the Usyukina-Davydychev (UD) functions may be reduced to two-fold MB transforms. The MB transforms were written there as polynomials of logarithms of ratios of squares of the external momenta with certain coefficients. We also showed that these coefficients have a combinatoric origin. In this paper we present an explicit formula for these coefficients. The procedure of recovering the coefficients is based on taking the double uni-form limit in certain series of smooth functions of two variables which is constructed according to a pre-determined iterative way. The result is obtained by using basic methods of mathematical analysis. We observe that the finiteness of the limit of this iterative chain of smooth functions should reflect itself in other mathematical constructions, too, since it is not related in any way to the explicit form of the MB transforms.

  17. Two-fold Mellin-Barnes transforms of Usyukina-Davydychev functions

    Energy Technology Data Exchange (ETDEWEB)

    Kniehl, Bernd [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik; Kondrashuk, Igor [Univ. del Bio Bio, Chillan (Chile). Dept. de Ciencias Basicas; Bielefeld Univ. (Germany). Fakultaet fuer Physik; Notte-Cuello, Eduardo A. [Univ. de La Serena (Chile). Dept. de Matematicas; Parra-Ferrada, Ivan [Univ. del Bio Bio, Chillan (Chile). Facultad de Educacion y Humanidades; Rojas-Medar, Marko [Univ. del Bio Bio, Chillan (Chile). Dept. de Ciencias Basicas

    2013-04-15

    In our previous paper (Nucl.Phys.B 870 (2013) 243) we showed that multi-fold Mellin-Barnes (MB) transforms of the Usyukina-Davydychev (UD) functions may be reduced to two-fold MB transforms. The MB transforms were written there as polynomials of logarithms of ratios of squares of the external momenta with certain coefficients. We also showed that these coefficients have a combinatoric origin. In this paper we present an explicit formula for these coefficients. The procedure of recovering the coefficients is based on taking the double uni-form limit in certain series of smooth functions of two variables which is constructed according to a pre-determined iterative way. The result is obtained by using basic methods of mathematical analysis. We observe that the finiteness of the limit of this iterative chain of smooth functions should reflect itself in other mathematical constructions, too, since it is not related in any way to the explicit form of the MB transforms.

  18. CONSERVATION PROCESS MODEL (CPM: A TWOFOLD SCIENTIFIC RESEARCH SCOPE IN THE INFORMATION MODELLING FOR CULTURAL HERITAGE

    Directory of Open Access Journals (Sweden)

    D. Fiorani

    2017-05-01

    Full Text Available The aim of the present research is to develop an instrument able to adequately support the conservation process by means of a twofold approach, based on both BIM environment and ontology formalisation. Although BIM has been successfully experimented within AEC (Architecture Engineering Construction field, it has showed many drawbacks for architectural heritage. To cope with unicity and more generally complexity of ancient buildings, applications so far developed have shown to poorly adapt BIM to conservation design with unsatisfactory results (Dore, Murphy 2013; Carrara 2014. In order to combine achievements reached within AEC through BIM environment (design control and management with an appropriate, semantically enriched and flexible The presented model has at its core a knowledge base developed through information ontologies and oriented around the formalization and computability of all the knowledge necessary for the full comprehension of the object of architectural heritage an its conservation. Such a knowledge representation is worked out upon conceptual categories defined above all within architectural criticism and conservation scope. The present paper aims at further extending the scope of conceptual modelling within cultural heritage conservation already formalized by the model. A special focus is directed on decay analysis and surfaces conservation project.

  19. Synthesis, crystal structure, and magnetic properties of a two-fold interpenetrated diamondoid open framework

    Science.gov (United States)

    Wu, Jing-Yun; Cheng, Fu-Yin; Chiang, Ming-Hsi

    2016-10-01

    Self-assembly of an enlarged angular pyridinecarboxylate ligand and cobalt(II) acetate under mild conditions afforded a three-dimensional open-framework coordination polymer, [Co2(μ-H2O)(pyca-43)4]n (1, Hpyca-43=(E)-3-((pyridin-4-yl)methyleneamino)benzoic acid). The molecular structure of 1 has rationalized to be a porous two-fold interpenetrated diamondoid-like network, with dinuclear Co2(μ-H2O)(O2C)4N4 clusters as tetrahedral secondary building units (SBUs), possessing highly solvent accessible volume of approximately 53.0%. Least-squares fit of the magnetic susceptibility data (20-300 K) of 1 yields Curie constant C=6.15 cm3 mol-1 K and Weiss constant θ=-11.6 K. Every Co2 subunit within the network is magnetically insulated to other dimers. The magnetic exchange parameter between Co(II) centers is estimated to -0.72 cm-1, suggesting a weak antiferromagnetic interaction. The gav value of 4.65 from fitting to the Lines model indicates that the decrease of the χMT value upon cooling is dominated by depopulation of the excited Kramer's states to the effective ground singlet. In addition, the thermal stability and adsorption properties of 1 are also reported.

  20. Intense green luminescence associated with two-fold coordinated Si in silica aerogel doped with ?

    Science.gov (United States)

    Li, Y. H.; Mo, C. M.; Yao, L. Z.; Liu, R. C.; Cai, W. L.; Li, X. M.; Wu, Z. Q.; Zhang, L. D.

    1998-02-01

    Amorphous silica aerogels doped with 0953-8984/10/7/013/img11 ions (SADAs) were prepared by the sol-gel route and supercritical drying. The visible luminescence of SADAs was measured and compared with that of porous silicon (PS), pure silica aerogels (PSAs) and silica xerogels doped with 0953-8984/10/7/013/img11 ions (SXDAs). The effect of annealing on the luminescence intensity of SADAs was investigated. Results show that (1) the luminescent intensity of as-prepared SADAs is much higher than that of as-prepared PSAs and SXDAs after annealing at 0953-8984/10/7/013/img13 (2) after annealing at 0953-8984/10/7/013/img14, the visible luminescence of SADAs is further substantially enhanced and becomes much higher than that of PS. However, for PSAs and SXDAs after annealing at 0953-8984/10/7/013/img14 the luminescent intensity is still kept at a very low value in comparison with that of SADAs. The strong visible luminescence appearing in SADAs is ascribed to significant amounts of the twofold coordinated Si (the 0953-8984/10/7/013/img16 (neutral) centre) in SADAs.

  1. Pseudo-unitary dynamics of free relativistic quantum mechanical twofold systems

    Science.gov (United States)

    Cardoso, J. G.

    2012-05-01

    A finite-dimensional pseudo-unitary framework is set up for describing the dynamics of free elementary particles in a purely relativistic quantum mechanical way. States of any individual particles or antiparticles are defined as suitably normalized vectors belonging to the two-complex-dimensional spaces that occur in local orthogonal decompositions of isomorphic copies of Cartan's space. The corresponding dynamical variables thus show up as bounded pseudo-Hermitian operator restrictions that possess real discrete spectra. Any measurement processes have to be performed locally in orthocronous proper Lorentz frames, but typical observational correlations are expressed in terms of symbolic configurations which come from the covariant action on spaces of state vectors of the Poincaré subgroup of an adequate realization of SU(2,2). The overall approach turns out to supply a supposedly natural description of the dynamics of free twofold systems in flat spacetime. One of the main outlooks devised here brings forward the possibility of carrying out methodically the construction of a background to a new relativistic theory of quantum information.

  2. Conservation Process Model (cpm): a Twofold Scientific Research Scope in the Information Modelling for Cultural Heritage

    Science.gov (United States)

    Fiorani, D.; Acierno, M.

    2017-05-01

    The aim of the present research is to develop an instrument able to adequately support the conservation process by means of a twofold approach, based on both BIM environment and ontology formalisation. Although BIM has been successfully experimented within AEC (Architecture Engineering Construction) field, it has showed many drawbacks for architectural heritage. To cope with unicity and more generally complexity of ancient buildings, applications so far developed have shown to poorly adapt BIM to conservation design with unsatisfactory results (Dore, Murphy 2013; Carrara 2014). In order to combine achievements reached within AEC through BIM environment (design control and management) with an appropriate, semantically enriched and flexible The presented model has at its core a knowledge base developed through information ontologies and oriented around the formalization and computability of all the knowledge necessary for the full comprehension of the object of architectural heritage an its conservation. Such a knowledge representation is worked out upon conceptual categories defined above all within architectural criticism and conservation scope. The present paper aims at further extending the scope of conceptual modelling within cultural heritage conservation already formalized by the model. A special focus is directed on decay analysis and surfaces conservation project.

  3. Theory for magnetic linear dichroism of electronic transitions between twofold-degenerate molecular spin levels

    Science.gov (United States)

    Bominaar, Emile L.; Achim, Catalina; Peterson, Jim

    1998-07-01

    Magnetic linear dichroism (MLD) spectroscopy is a relatively new technique which previously has been almost exclusively applied to atoms. These investigations have revealed that the study of MLD, in conjunction with electronic absorption and magnetic circular dichroism (MCD) spectroscopies, provides significant additional information concerning the electronic structure of atoms. More recent measurements have indicated that MLD is also observable from transition ions in inorganic compounds and metalloproteins. While the theory for atomic MLD has been worked out in considerable detail during the last two decades, an MLD theory of practical utility for the analysis of the spectra derived from the majority of paramagnetic molecules is not available. In the present contribution, the MLD of an electric-dipole-allowed transition between twofold-degenerate molecular spin levels is analyzed, assuming nonsaturating conditions. As for atomic systems, it is found that the MLD of a single molecule is dominated by the term G0. However, this term vanishes in the powder average evaluated for a randomly oriented ensemble of molecules, leading to a drastic reduction of the MLD differential absorption for systems with spin S=1/2 compared to that observed for systems with higher ground-state spin. It is found that MLD and MCD spectroscopies on solution samples have complementary spin-state specific sensitivities which suggest that the two methods can be used to selectively probe the individual metal sites in multicenter metalloprotein assemblies.

  4. A twofold quantum delayed-choice experiment in a superconducting circuit.

    Science.gov (United States)

    Liu, Ke; Xu, Yuan; Wang, Weiting; Zheng, Shi-Biao; Roy, Tanay; Kundu, Suman; Chand, Madhavi; Ranadive, Arpit; Vijay, Rajamani; Song, Yipu; Duan, Luming; Sun, Luyan

    2017-05-01

    Wave-particle complementarity lies at the heart of quantum mechanics. To illustrate this mysterious feature, Wheeler proposed the delayed-choice experiment, where a quantum system manifests the wave- or particle-like attribute, depending on the experimental arrangement, which is made after the system has entered the interferometer. In recent quantum delayed-choice experiments, these two complementary behaviors were simultaneously observed with a quantum interferometer in a superposition of being closed and open. We suggest and implement a conceptually different quantum delayed-choice experiment by introducing a which-path detector (WPD) that can simultaneously record and neglect the system's path information, but where the interferometer itself is classical. Our experiment is realized with a superconducting circuit, where a cavity acts as the WPD for an interfering qubit. Using this setup, we implement the first twofold delayed-choice experiment, which demonstrates that the system's behavior depends not only on the measuring device's configuration that can be chosen even after the system has been detected but also on whether we a posteriori erase or mark the which-path information, the latter of which cannot be revealed by previous quantum delayed-choice experiments. Our results represent the first demonstration of both counterintuitive features with the same experimental setup, significantly extending the concept of quantum delayed-choice experiment.

  5. Effects on circulating steroid hormones and gene expression along the hypothalamus–pituitary–gonadal axis in adult Japanese quail exposed to 17β-trenbolone across multiple generations

    Science.gov (United States)

    Karouna, Natalie; Chen, Yu; Henry, Paula F.; Maddox, Catherine M.; Sprague, Dan

    2017-01-01

    We investigated the effects of the androgenic growth promoter 17β-trenbolone (17βTB) on adult Japanese quail (Coturnix japonica) exposed across three generations. The F0 generation was exposed after sexual maturity to 0, 1, 5, 10, 20, and 40 ppm through feed. The F1 generation was exposed in ovo by maternal transfer and through feed at the same doses as their parents. The F2 generation was exposed in ovo only. Levels of plasma sex steroids, gonadal Cytochrome P450 aromatase (CYP19A1) mRNA and select brain neuroendocrine peptide mRNAs were measured. In males, testosterone levels did not differ in any generation from those in controls. Estradiol was significantly elevated in 17βTB treated F0 and F1 males. In F0 and F1 females, testosterone was suppressed by 17βTB, whereas estradiol was significantly higher at 40 ppm in F0 and at 10 ppm in F1 females. CYP19A1 expression in F1 males and females increased suggesting a compensatory response to the androgenic effects of 17βTB. Few significant effects were observed in the F2 birds indicating that in ovo exposure had limited effects on the monitored endpoints. Overall, our results confirmed endocrine disrupting effects of dietary 17βTB in Japanese quail but the response was dependent on sex, developmental stage at initiation of exposure, and dose.

  6. AAV8 capsid variable regions at the two-fold symmetry axis contribute to high liver transduction by mediating nuclear entry and capsid uncoating

    Energy Technology Data Exchange (ETDEWEB)

    Tenney, Rebeca M.; Bell, Christie L.; Wilson, James M., E-mail: wilsonjm@mail.med.upenn.edu

    2014-04-15

    Adeno-associated virus serotype 8 (AAV8) is a promising vector for liver-directed gene therapy. Although efficient uncoating of viral capsids has been implicated in AAV8's robust liver transduction, much about the biology of AAV8 hepatotropism remains unclear. Our study investigated the structural basis of AAV8 liver transduction efficiency by constructing chimeric vector capsids containing sequences derived from AAV8 and AAV2 – a highly homologous yet poorly hepatotropic serotype. Engineered vectors containing capsid variable regions (VR) VII and IX from AAV8 in an AAV2 backbone mediated near AAV8-like transduction in mouse liver, with higher numbers of chimeric genomes detected in whole liver cells and isolated nuclei. Interestingly, chimeric capsids within liver nuclei also uncoated similarly to AAV8 by 6 weeks after administration, in contrast with AAV2, of which a significantly smaller proportion were uncoated. This study links specific AAV capsid regions to the transduction ability of a clinically relevant AAV serotype. - Highlights: • We construct chimeric vectors to identify determinants of AAV8 liver transduction. • An AAV2-based vector with 17 AAV8 residues exhibited high liver transduction in mice. • This vector also surpassed AAV2 in cell entry, nuclear entry and onset of expression. • Most chimeric vector particles were uncoated at 6 weeks, like AAV8 and unlike AAV2. • Chimera retained heparin binding and was antigenically distinct from AAV2 and AAV8.

  7. The Twofold Multidimensionality of Academic Self-Concept: Domain Specificity and Separation between Competence and Affect Components

    Science.gov (United States)

    Arens, A. Katrin; Yeung, Alexander Seeshing; Craven, Rhonda G.; Hasselhorn, Marcus

    2011-01-01

    Academic self-concept is consistently proven to be multidimensional rather than unidimensional as it is domain specific in nature. However, each specific self-concept domain may be further separated into competence and affect components. This study examines the twofold multidimensionality of academic self-concept (i.e., its domain specificity and…

  8. Breaking pseudo-twofold symmetry in the poliovirus 3'-UTR Y-stem by restoring Watson-Crick base pairs

    NARCIS (Netherlands)

    Zoll, G.J.; Tessari, M.; Kuppeveld, F.J.M. van; Melchers, W.J.G.; Heus, H.A.

    2007-01-01

    The previously described NMR structure of a 5'-CU-3'/5'-UU-3' motif, which is highly conserved within the 3'-UTR Y-stem of poliovirus-like enteroviruses, revealed striking regularities of the local helix geometry, thus retaining the pseudo-twofold symmetry of the RNA helix. A mutant virus with both

  9. Breaking pseudo-twofold symmetry in the poliovirus 3'-UTR Y-stem by restoring Watson-Crick base pairs.

    NARCIS (Netherlands)

    Zoll, G.J.; Tessari, M.; Kuppeveld, F.J.M. van; Melchers, W.J.G.; Heus, H.A.

    2007-01-01

    The previously described NMR structure of a 5'-CU-3'/5'-UU-3' motif, which is highly conserved within the 3'-UTR Y-stem of poliovirus-like enteroviruses, revealed striking regularities of the local helix geometry, thus retaining the pseudo-twofold symmetry of the RNA helix. A mutant virus with both

  10. Twofold reduction of phosphofructokinase activity in Lactococcus lactis results in strong decreases in growth rate and in glycolytic flux

    DEFF Research Database (Denmark)

    Andersen, Heidi Winterberg; Solem, Christian; Hammer, Karin;

    2001-01-01

    Two mutant strains of Lactococcus lactis in which the promoter of the las operon, harboring pfk, pyk, and ldh, were replaced by synthetic promoters were constructed. These las mutants had an approximately twofold decrease in the activity of phosphofructokinase, whereas the activities of pyruvate...

  11. Conformation and sequence evidence for two-fold symmetry in left-handed beta-helix fold.

    Science.gov (United States)

    Shen, Xiaojuan

    2011-09-21

    The left-handed beta-helix (LβH) has received interest recently as it folds as a possible solution for the structure of misfolded proteins associated with prion and Huntington's diseases. Through a combination of sequence and structure analysis, we uncover a novel feature that is common to this unique fold: a two-fold symmetry in both sequence and structure, and this feature always coupled with extended loops in the middle of the helix. Since the results reveal a two-fold symmetric pattern both in the sequence and structure, it may indicate that the symmetry in tertiary structure is coded by the symmetry in primary sequence, which agrees with Anfisen's proposal that a protein's amino-acid sequence specify its three-dimensional structure. It may also indicate that LβH adopts a two-fold repeat pattern during the evolution process and symmetry helps maintaining the stability of the helix structure. The two-fold symmetric pattern and extended loops might be important in maintaining stability of helix proteins. This discovery can be useful in understanding the folding mechanisms of this protein fold and provide insights in the relation between sequences and structures.

  12. Fetal and Neonatal HPA Axis.

    Science.gov (United States)

    Wood, Charles E; Walker, Claire-Dominique

    2015-12-15

    Stress is an integral part of life. Activation of the hypothalamus-pituitary-adrenal (HPA) axis in the adult can be viewed as mostly adaptive to restore homeostasis in the short term. When stress occurs during development, and specifically during periods of vulnerability in maturing systems, it can significantly reprogram function, leading to pathologies in the adult. Thus, it is critical to understand how the HPA axis is regulated during developmental periods and what are the factors contributing to shape its activity and reactivity to environmental stressors. The HPA axis is not a passive system. It can actively participate in critical physiological regulation, inducing parturition in the sheep for instance or being a center stage actor in the preparation of the fetus to aerobic life (lung maturation). It is also a major player in orchestrating mental function, metabolic, and cardiovascular function often reprogrammed by stressors even prior to conception through epigenetic modifications of gametes. In this review, we review the ontogeny of the HPA axis with an emphasis on two species that have been widely studied-sheep and rodents-because they each share many similar regulatory mechanism applicable to our understanding of the human HPA axis. The studies discussed in this review should ultimately inform us about windows of susceptibility in the developing brain and the crucial importance of early preconception, prenatal, and postnatal interventions designed to improve parental competence and offspring outcome. Only through informed studies will our public health system be able to curb the expansion of many stress-related or stress-induced pathologies and forge a better future for upcoming generations.

  13. Single-Axis Accelerometer

    Science.gov (United States)

    Tucker, Dennis Stephen (Inventor); Capo-Lugo, Pedro A. (Inventor)

    2016-01-01

    A single-axis accelerometer includes a housing defining a sleeve. An object/mass is disposed in the sleeve for sliding movement therein in a direction aligned with the sleeve's longitudinal axis. A first piezoelectric strip, attached to a first side of the object and to the housing, is longitudinally aligned with the sleeve's longitudinal axis. The first piezoelectric strip includes a first strip of a piezoelectric material with carbon nanotubes substantially aligned along a length thereof. A second piezoelectric strip, attached to a second side of the object and to the housing, is longitudinally aligned with the sleeve's longitudinal axis. The second piezoelectric strip includes a second strip of the piezoelectric material with carbon nanotubes substantially aligned along a length thereof. A voltage sensor is electrically coupled to at least one of the first and second piezoelectric strips.

  14. UMAPRM: Uniformly sampling the medial axis

    KAUST Repository

    Yeh, Hsin-Yi Cindy

    2014-05-01

    © 2014 IEEE. Maintaining clearance, or distance from obstacles, is a vital component of successful motion planning algorithms. Maintaining high clearance often creates safer paths for robots. Contemporary sampling-based planning algorithms That utilize The medial axis, or The set of all points equidistant To Two or more obstacles, produce higher clearance paths. However, They are biased heavily Toward certain portions of The medial axis, sometimes ignoring parts critical To planning, e.g., specific Types of narrow passages. We introduce Uniform Medial Axis Probabilistic RoadMap (UMAPRM), a novel planning variant That generates samples uniformly on The medial axis of The free portion of Cspace. We Theoretically analyze The distribution generated by UMAPRM and show its uniformity. Our results show That UMAPRM\\'s distribution of samples along The medial axis is not only uniform but also preferable To other medial axis samplers in certain planning problems. We demonstrate That UMAPRM has negligible computational overhead over other sampling Techniques and can solve problems The others could not, e.g., a bug Trap. Finally, we demonstrate UMAPRM successfully generates higher clearance paths in The examples.

  15. 竖轴水轮机式潮流能发电装置开发现状与发展趋势%Developing Status and Development Trend of Vertical Axis Turbine-type Tidal Current Energy Power Generation Device

    Institute of Scientific and Technical Information of China (English)

    马勇; 张亮; 马良; 陈展

    2012-01-01

    世界能源日趋紧张,而环境污染不断加剧.潮流能作为清洁无污染的绿色可再生新能源,具有储量大、分布广、可预测性强、环境污染小等特点,开发利用潮流能对缓解能源紧张、降低环境污染具有重要的现实意义.潮流能利用的主要形式是利用潮流能发电装置发电,其原理是:潮流冲击水轮机,将潮流水平流动的动能转换为水轮机的机械能,水轮机经机械传动装置,带动发电机发电,将机械能转换为电能.潮流能发电装置根据水轮机结构形式的不同,分为水平轴式、竖轴式和横轴式.与水平轴水轮机式和横轴水轮机式潮流能发电装置相比,竖轴水轮机式潮流能发电装置具有适应流向性强,适合大规模阵列布置等特点,具有独特的应用优势.本文针对竖轴水轮机式潮流能发电装置,阐述发电装置的开发现状,分析不同结构形式发电装置的特点,指出竖轴水轮机式潮流能发电装置的发展趋势和关键技术,为竖轴潮流能发电装置的理论研究与工程应用提供参考和借鉴.%Energy shortage and environment pollutes aggravate ceaselessly all over the world. As a green clean pollution-free renewable energy, tidal current energy has characteristics such as large reserves, wide distribution, predictability, little environmental pollution, etc. Development and utilization of tidal energy has important practical significance to ease the energy shortage and reduce the pollution of the environment. The main form to utilize tidal energy is to generate power, this paper studies the vertical axis turbine-type tidal current energy power generation device, describes the present development situation of the power generation device which could be divided into three kinds, namely the floating structures, the seabed piled structures and the sit seabed structures, analyzes the characteristic of different structural forms of the power generation device, pointed

  16. The Chinese Baptists: An example of a twofold minority in Serbia today

    Directory of Open Access Journals (Sweden)

    Blagojević Gordana

    2011-01-01

    Full Text Available A more massive migration of Chinese to Serbia can be traced back to the 1990s. The Chinese in Serbia represent the first generation of migrants who came out of economic reasons. This work deals with the role of their religious identity in the gathering of those members of the group who practice Baptist Christianity. Baptist Christians are a religious minority both in China and Serbia. Therefore, the members of this group represent a double minority: both in the reception country (religious and national and in their own country, compared to the religious orientation of the majority of their fellow countrymen. Apart from this, their church services are marked by certain characteristics by which they can be distinguished from other Baptist groups. The role of the religious factor in the community’s life is being viewed here, as well as the affirmation and making connections between the members.

  17. Generations.

    Science.gov (United States)

    Chambers, David W

    2005-01-01

    Groups naturally promote their strengths and prefer values and rules that give them an identity and an advantage. This shows up as generational tensions across cohorts who share common experiences, including common elders. Dramatic cultural events in America since 1925 can help create an understanding of the differing value structures of the Silents, the Boomers, Gen Xers, and the Millennials. Differences in how these generations see motivation and values, fundamental reality, relations with others, and work are presented, as are some applications of these differences to the dental profession.

  18. A two-fold interpenetrated flexible bi-pillared-layer framework of Fe(II) with interesting solvent adsorption property

    Indian Academy of Sciences (India)

    Ritesh Haldar; Tapas Kumar Majia

    2011-11-01

    A two-fold interpenetrated microporous bi-pillared-layer framework of Fe(II), {[Fe(2,6-napdc)(4,4'-bipy)](EtOH)(H2O)} (1) (2,6-napdc =2,6-naphthalenedicarboxylate; 4,4'-bipy=4,4'-bipyridine) composed of mixed ligand system has been synthesized and structurally characterized. The 2,6-napdc linkers form a 2D corrugated sheet of {Fe(2,6-napdc)} by linking the secondary building unit of Fe2(CO2)2 in the plane, which are further connected by double 4,4'-bipy pillars resulting in a bi-pillared-layer type 3D framework. The 3D framework is two-fold interpenetrated and exhibits a 3D channel structure (4.0 × 3.5, 1.5 × 0.5 and 2.2 × 2.1 Å2) occupied by the guest water and ethanol molecules. Framework 1 shows high thermal stability, and the desolvated framework (1′) renders permanent porosity realized by N2 adsorption profile at 77K (BET surface area of ∼ 52 m2 g-1). Moreover, the framework 1′ also uptakes different solvent vapours (water, methanol and ethanol) and their type-I profile suggest strong interaction with pore surfaces and overall hydrophilic nature of the framework. Temperature dependent magnetic measurements suggest overall antiferromagnetic behaviour in compound 1.

  19. POGAL B-Axis Motor Test

    Energy Technology Data Exchange (ETDEWEB)

    Hale, L C; Wulff, T A

    2004-06-28

    The Aerotech model S-180-69-A, a brushless DC motor of slotless design, was selected as the B-axis drive for the Precision Optical Grinder and Lathe (POGAL). It is common knowledge that a slotless motor will have effectively no magnetic cogging and much less torque ripple than a traditional slot-type motor. It is logical to believe that the radial and axial forces generated between the rotor and stator would also be smaller for a slotless design. This is important when a frameless motor is directly coupled to the axis, as these forces directly influence the axis and affect its error motion. It is the purpose of this test to determine the radial and axial forces generated by the Aerotech motor and to estimate their effect on the error motion of the axis using a mathematical model of the hydrostatic bearing being designed for POGAL. The test results combined with a mathematical model of the POGAL B axis indicate that the directly coupled Aerotech motor will be quite acceptable. In the radial direction, the residual motor force, after subtracting out the one-cycle force, could cause sub nanometer level error motion at the tool point. The axial direction is not in a sensitive direction for turning.

  20. Oblique Axis Body Fracture

    DEFF Research Database (Denmark)

    Takai, Hirokazu; Konstantinidis, Lukas; Schmal, Hagen;

    2016-01-01

    was uneventful. Conclusions. Oblique type axis body fractures resemble a highly unstable subtype of Anderson type III fractures with the potential of severe secondary deformity following conservative treatment, irrespective of initial grade of displacement. The authors therefore warrant a high index of suspicion......Purpose. Anderson type III odontoid fractures have traditionally been considered stable and treated conservatively. However, unstable cases with unfavorable results following conservative treatment have been reported. Methods. We present the cases of two patients who sustained minimally displaced...

  1. Lithium Salt of NH2-substituted Graphene Nanoribbon with Twofold Donor-acceptor Framework: Large Nonlinear Optical Property

    Institute of Scientific and Technical Information of China (English)

    ZHOU Zhong-jun; LI Zhi-ru; HUANG Xu-ri; SUN Chia-chung

    2011-01-01

    Based on graphene, a new class of second-order nonlinear optical(NLO) material, the lithium salt of NH2-substituted graphene nanoribbon with the twofold donor(D)/acceptor(A) mode, was reported. Eight stable 2Li-2NH2-GNR lithium salts, especially cis lithium salts, display considerably large ,β0 values. The combination of NH2-substituting and cis Li-doping makes β0 greatly increased from 0(GNR) to 1.2×105-2.9×105 a.u.(cis-2Li2NH2-GNRs). Our largest β0 value(2.9× l05 a.u.) for cis-2Li-1,3-2NH2-AGNR is comparable to the record value of 1.7× l05 a.u. for a long donor-acceptor polyene.

  2. T4 fibrations over Calabi–Yau two-folds and non-Kähler manifolds in string theory

    Directory of Open Access Journals (Sweden)

    Hai Lin

    2016-08-01

    Full Text Available We construct a geometric model of eight-dimensional manifolds and realize them in the context of type II string theory. These eight-manifolds are constructed by non-trivial T4 fibrations over Calabi–Yau two-folds. These give rise to eight-dimensional non-Kähler Hermitian manifolds with SU(4 structure. The eight-manifold is also a circle fibration over a seven-dimensional G2 manifold with skew torsion. The eight-manifolds of this type appear as internal manifolds with SU(4 structure in type IIB string theory with F3 and F7 fluxes. These manifolds have generalized calibrated cycles in the presence of fluxes.

  3. Complex Structure of the Four-Dimensional Kerr Geometry: Stringy System, Kerr Theorem, and Calabi-Yau Twofold

    Directory of Open Access Journals (Sweden)

    Alexander Burinskii

    2013-01-01

    Full Text Available The 4D Kerr geometry displays many wonderful relations with quantum world and, in particular, with superstring theory. The lightlike structure of fields near the Kerr singular ring is similar to the structure of Sen solution for a closed heterotic string. Another string, open and complex, appears in the complex representation of the Kerr geometry initiated by Newman. Combination of these strings forms a membrane source of the Kerr geometry which is parallel to the structure of M-theory. In this paper we give one more evidence of this relationship, emergence of the Calabi-Yau twofold (K3 surface in twistorial structure of the Kerr geometry as a consequence of the Kerr theorem. Finally, we indicate that the Kerr stringy system may correspond to a complex embedding of the critical N = 2 superstring.

  4. The axis of evil

    CERN Document Server

    Land, K; Land, Kate; Magueijo, Joao

    2005-01-01

    We examine previous claims for a preferred axis at $(b,l)\\approx (60,-100)$ in the cosmic radiation anisotropy, by generalizing the concept of multipole planarity to any shape preference (a concept we define mathematically). Contrary to earlier claims, we find that the amount of power concentrated in planar modes for $\\ell=2,3$ is not inconsistent with isotropy and Gaussianity. The multipoles' alignment, however, is indeed anomalous, and extends up to $\\ell=5$ rejecting statistical isotropy with a probability in excess of 99.9%. There is also an uncanny correlation of azimuthal phases between $\\ell=3$ and $\\ell=5$. We are unable to blame these effects on foreground contamination or large-scale systematic errors. We show how this reappraisal may be crucial in identifying the theoretical model behind the anomaly.

  5. Preferred axis in cosmology

    CERN Document Server

    Zhao, Wen

    2016-01-01

    The foundation of modern cosmology relies on the so-called cosmological principle which states an homogeneous and isotropic distribution of matter in the universe on large scales. However, recent observations, such as the temperature anisotropy of the cosmic microwave background (CMB) radiation, the motion of galaxies in the universe, the polarization of quasars and the acceleration of the cosmic expansion, indicate preferred directions in the sky. If these directions have a cosmological origin, the cosmological principle would be violated, and modern cosmology should be reconsidered. In this paper, by considering the preferred axis in the CMB parity violation, we find that it coincides with the preferred axes in CMB quadrupole and CMB octopole, and they all align with the direction of the CMB kinematic dipole. In addition, the preferred directions in the velocity flows, quasar alignment, anisotropy of the cosmic acceleration, the handedness of spiral galaxies, and the angular distribution of the fine-structu...

  6. Oblique Axis Body Fracture

    DEFF Research Database (Denmark)

    Takai, Hirokazu; Konstantinidis, Lukas; Schmal, Hagen

    2016-01-01

    Purpose. Anderson type III odontoid fractures have traditionally been considered stable and treated conservatively. However, unstable cases with unfavorable results following conservative treatment have been reported. Methods. We present the cases of two patients who sustained minimally displaced...... Anderson type III fractures with a characteristic fracture pattern that we refer to as "oblique type axis body fracture." Results. The female patients aged 90 and 72 years, respectively, were both diagnosed with minimally displaced Anderson type III fractures. Both fractures had a characteristic "oblique...... type" fracture pattern. The first patient was treated conservatively with cervical spine immobilization in a semirigid collar. However, gross displacement was noted at the 6-week follow-up visit. The second patient was therefore treated operatively by C1-C3/4 posterior fusion and the course...

  7. 康德论美的双重特性%Kant on the Twofold Logical Peculiarity of Beauty

    Institute of Scientific and Technical Information of China (English)

    王奎

    2015-01-01

    与认识和道德不同,康德认为美具有一种双重的逻辑特性:“好像主观性”和“好像客观性”。一方面美以个人的情感而非概念为基础,不能通过经验归纳或理性演绎而得到证明,因而好像是主观的;另一方面,美同经验判断一样要求人们的普遍同意,好像又是客观的。美的本质体现在主客体之间的这种关系,既不是纯然主观的,也不是客观的,任何将美还原为单纯主观性或客观性的观点都是对康德美学的误读。康德美学的独特性就在于这两种看似矛盾的特性在审美判断中可以共存。%s:In contrast with cognitive and moral judgments,Kant holds that the beauty has a twofold logical peculiarity,namely〞as if subjectivity〞and〞as if objectivity〞.On one hand,grounded on one's own feeling rather than any concept,the judgment of taste cannot be confirmed or disconfirmed through empiri-cal induction or rational deduction,just as if it were subjective.On the other hand,like empirical judg-ments,the beauty requires the assent of everyone,as if it were objective.The beauty is therefore neither purely subjective nor objective,and is best to be described as relation of object to the subject.In this con-text,the view that reduces the beauty to mere subjectivity or objectivity is obviously a misunderstanding of Kant's intentions.It is characteristic of Kant's aesthetics that the twofold seeming paradoxical peculiarity can coexist in a single judgment of taste.

  8. Enhanced ultraviolet emission and its irreversible temperature antiquenching behavior of twofold coordinated silicon centers in silica glass

    Science.gov (United States)

    Nagayoshi, Yu; Uchino, Takashi

    2016-10-01

    It has been well documented that an oxygen divacancy center, or a twofold-coordinated Si center, in silica glass yields a singlet-to-singlet photoluminescence (PL) emission at 4.4 eV with a decay time of ˜4 ns. Although the 4.4-eV PL band is interesting in terms of a deep-ultraviolet light emitter, the emission efficiency has been too low to be considered for a practical application. In this work, we show that a highly luminescent silica glass, with an internal quantum yield of 68% for the 4.4-eV PL band at room temperature, can be prepared when micrometer-sized silica powders are heat treated at ˜1900 °C under inert gas atmosphere by using a high-frequency induction heating unit equipped with a graphite crucible. We also show that the intensity of the 4.4-eV emission in the thus prepared silica glass exhibits an irreversible temperature antiquenching behavior in the temperature region below ˜320 K during heating-cooling cycles. The anomalous temperature dependencies of the 4.4-eV emission can be interpreted in terms of thermally activated trapping-detrapping processes of photoexcited electrons associated with deep trap states.

  9. An unprecedented two-fold nested super-polyrotaxane: sulfate-directed hierarchical polythreading assembly of uranyl polyrotaxane moieties

    Energy Technology Data Exchange (ETDEWEB)

    Mei, Lei; Wu, Qun-yan; Yuan, Li-yong; Wang, Lin; An, Shu-wen; Xie, Zhen-ni; Hu, Kong-qiu; Shi, Wei-qun [Laboratory of Nuclear Energy Chemistry and Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing (China); Chai, Zhi-fang [Laboratory of Nuclear Energy Chemistry and Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing (China); School of Radiological and Interdisciplinary Sciences and Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou (China); Burns, Peter C. [Department of Chemistry and Biochemistry, University of Notre Dame, IN (United States)

    2016-08-01

    The hierarchical assembly of well-organized submoieties could lead to more complicated superstructures with intriguing properties. We describe herein an unprecedented polyrotaxane polythreading framework containing a two-fold nested super-polyrotaxane substructure, which was synthesized through a uranyl-directed hierarchical polythreading assembly of one-dimensional polyrotaxane chains and two-dimensional polyrotaxane networks. This special assembly mode actually affords a new way of supramolecular chemistry instead of covalently linked bulky stoppers to construct stable interlocked rotaxane moieties. An investigation of the synthesis condition shows that sulfate can assume a vital role in mediating the formation of different uranyl species, especially the unique trinuclear uranyl moiety [(UO{sub 2}){sub 3}O(OH){sub 2}]{sup 2+}, involving a notable bent [O=U=O] bond with a bond angle of 172.0(9) . Detailed analysis of the coordination features, the thermal stability as well as a fluorescence, and electrochemical characterization demonstrate that the uniqueness of this super-polyrotaxane structure is mainly closely related to the trinuclear uranyl moiety, which is confirmed by quantum chemical calculations. (copyright 2016 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  10. Cross-axis adaptation of torsional components in the yaw-axis vestibulo-ocular reflex

    Science.gov (United States)

    Trillenberg, P.; Shelhamer, M.; Roberts, D. C.; Zee, D. S.

    2003-01-01

    The three pairs of semicircular canals within the labyrinth are not perfectly aligned with the pulling directions of the six extraocular muscles. Therefore, for a given head movement, the vestibulo-ocular reflex (VOR) depends upon central neural mechanisms that couple the canals to the muscles with the appropriate functional gains in order to generate a response that rotates the eye the correct amount and around the correct axis. A consequence of these neural connections is a cross-axis adaptive capability, which can be stimulated experimentally when head rotation is around one axis and visual motion about another. From this visual-vestibular conflict the brain infers that the slow-phase eye movement is rotating around the wrong axis. We explored the capability of human cross-axis adaptation, using a short-term training paradigm, to determine if torsional eye movements could be elicited by yaw (horizontal) head rotation (where torsion is normally inappropriate). We applied yaw sinusoidal head rotation (+/-10 degrees, 0.33 Hz) and measured eye movement responses in the dark, and before and after adaptation. The adaptation paradigm lasted 45-60 min, and consisted of the identical head motion, coupled with a moving visual scene that required one of several types of eye movements: (1) torsion alone (-Roll); (2) horizontal/torsional, head right/CW torsion (Yaw-Roll); (3) horizontal/torsional, head right/CCW torsion (Yaw+Roll); (4) horizontal, vertical, torsional combined (Yaw+Pitch-Roll); and (5) horizontal and vertical together (Yaw+Pitch). The largest and most significant changes in torsional amplitude occurred in the Yaw-Roll and Yaw+Roll conditions. We conclude that short-term, cross-axis adaptation of torsion is possible but constrained by the complexity of the adaptation task: smaller torsional components are produced if more than one cross-coupling component is required. In contrast, vertical cross-axis components can be easily trained to occur with yaw head

  11. Gut Microbiota-brain Axis

    OpenAIRE

    2016-01-01

    Objective: To systematically review the updated information about the gut microbiota-brain axis. Data Sources: All articles about gut microbiota-brain axis published up to July 18, 2016, were identified through a literature search on PubMed, ScienceDirect, and Web of Science, with the keywords of “gut microbiota”, “gut-brain axis”, and “neuroscience”. Study Selection: All relevant articles on gut microbiota and gut-brain axis were included and carefully reviewed, with no limitation of s...

  12. Gut Microbiota-brain Axis

    Institute of Scientific and Technical Information of China (English)

    Hong-Xing Wang; Yu-Ping Wang

    2016-01-01

    Objective:To systematically review the updated information about the gut microbiota-brain axis.Data Sources:All articles about gut microbiota-brain axis published up to July 18,2016,were identified through a literature search on PubMed,ScienceDirect,and Web of Science,with the keywords of"gut microbiota","gut-brain axis",and "neuroscience".Study Selection:All relevant articles on gut microbiota and gut-brain axis were included and carefully reviewed,with no limitation of study design.Results:It is well-recognized that gut microbiota affects the brain's physiological,behavioral,and cognitive functions although its precise mechanism has not yet been fully understood.Gut microbiota-brain axis may include gut microbiota and their metabolic products,enteric nervous system,sympathetic and parasympathetic branches within the autonomic nervous system,neural-immune system,neuroendocrine system,and central nervous system.Moreover,there may be five communication routes between gut microbiota and brain,including the gut-brain's neural network,neuroendocrine-hypothalamic-pituitary-adrenal axis,gut immune system,some neurotransmitters and neural regulators synthesized by gut bacteria,and barrier paths including intestinal mucosal barrier and blood-brain barrier.The microbiome is used to define the composition and functional characteristics of gut microbiota,and metagenomics is an appropriate technique to characterize gut microbiota.Conclusions:Gut microbiota-brain axis refers to a bidirectional information network between the gut microbiota and the brain,which may provide a new way to protect the brain in the near future.

  13. A Method for Modeling of Floating Vertical Axis Wind Turbine

    DEFF Research Database (Denmark)

    Wang, Kai; Hansen, Martin Otto Laver; Moan, Torgeir

    2013-01-01

    . In order to assess the technical and economic feasibility of this novel concept, a comprehensive simulation tool for modeling of the floating vertical axis wind turbine is needed. This work presents the development of a coupled method for modeling of the dynamics of a floating vertical axis wind turbine......It is of interest to investigate the potential advantages of floating vertical axis wind turbine (FVAWT) due to its economical installation and maintenance. A novel 5MW vertical axis wind turbine concept with a Darrieus rotor mounted on a semi-submersible support structure is proposed in this paper....... This integrated dynamic model takes into account the wind inflow, aerodynamics, hydrodynamics, structural dynamics (wind turbine, floating platform and the mooring lines) and a generator control. This approach calculates dynamic equilibrium at each time step and takes account of the interaction between the rotor...

  14. Vertical axis wind turbine airfoil

    Science.gov (United States)

    Krivcov, Vladimir; Krivospitski, Vladimir; Maksimov, Vasili; Halstead, Richard; Grahov, Jurij Vasiljevich

    2012-12-18

    A vertical axis wind turbine airfoil is described. The wind turbine airfoil can include a leading edge, a trailing edge, an upper curved surface, a lower curved surface, and a centerline running between the upper surface and the lower surface and from the leading edge to the trailing edge. The airfoil can be configured so that the distance between the centerline and the upper surface is the same as the distance between the centerline and the lower surface at all points along the length of the airfoil. A plurality of such airfoils can be included in a vertical axis wind turbine. These airfoils can be vertically disposed and can rotate about a vertical axis.

  15. Gut Microbiota-brain Axis

    Science.gov (United States)

    Wang, Hong-Xing; Wang, Yu-Ping

    2016-01-01

    Objective: To systematically review the updated information about the gut microbiota-brain axis. Data Sources: All articles about gut microbiota-brain axis published up to July 18, 2016, were identified through a literature search on PubMed, ScienceDirect, and Web of Science, with the keywords of “gut microbiota”, “gut-brain axis”, and “neuroscience”. Study Selection: All relevant articles on gut microbiota and gut-brain axis were included and carefully reviewed, with no limitation of study design. Results: It is well-recognized that gut microbiota affects the brain's physiological, behavioral, and cognitive functions although its precise mechanism has not yet been fully understood. Gut microbiota-brain axis may include gut microbiota and their metabolic products, enteric nervous system, sympathetic and parasympathetic branches within the autonomic nervous system, neural-immune system, neuroendocrine system, and central nervous system. Moreover, there may be five communication routes between gut microbiota and brain, including the gut-brain's neural network, neuroendocrine-hypothalamic-pituitary-adrenal axis, gut immune system, some neurotransmitters and neural regulators synthesized by gut bacteria, and barrier paths including intestinal mucosal barrier and blood-brain barrier. The microbiome is used to define the composition and functional characteristics of gut microbiota, and metagenomics is an appropriate technique to characterize gut microbiota. Conclusions: Gut microbiota-brain axis refers to a bidirectional information network between the gut microbiota and the brain, which may provide a new way to protect the brain in the near future. PMID:27647198

  16. Electrostatic generator/motor configurations

    Science.gov (United States)

    Post, Richard F

    2014-02-04

    Electrostatic generators/motors designs are provided that generally may include a first cylindrical stator centered about a longitudinal axis; a second cylindrical stator centered about the axis, a first cylindrical rotor centered about the axis and located between the first cylindrical stator and the second cylindrical stator. The first cylindrical stator, the second cylindrical stator and the first cylindrical rotor may be concentrically aligned. A magnetic field having field lines about parallel with the longitudinal axis is provided.

  17. Two-axis angular effector

    Energy Technology Data Exchange (ETDEWEB)

    Vaughn, Mark R. (Albuquerque, NM); Robinett, III, Rush D. (Tijeras, NM); Phelan, John R. (Albuquerque, NM); Van Zuiden, Don M. (Albuquerque, NM)

    1997-01-21

    A new class of coplanar two-axis angular effectors. These effectors combine a two-axis rotational joint analogous to a Cardan joint with linear actuators in a manner to produce a wider range of rotational motion about both axes defined by the joint. This new class of effectors also allows design of robotic manipulators having very high strength and efficiency. These effectors are particularly suited for remote operation in unknown surroundings, because of their extraordinary versatility. An immediate application is to the problems which arise in nuclear waste remediation.

  18. Two-axis angular effector

    Energy Technology Data Exchange (ETDEWEB)

    Vaughn, M.R.; Robinett, R.D. III; Phelan, J.R.; Zuiden, D.M. Van

    1997-01-21

    A new class of coplanar two-axis angular effectors is described. These effectors combine a two-axis rotational joint analogous to a Cardan joint with linear actuators in a manner to produce a wider range of rotational motion about both axes defined by the joint. This new class of effectors also allows design of robotic manipulators having very high strength and efficiency. These effectors are particularly suited for remote operation in unknown surroundings, because of their extraordinary versatility. An immediate application is to the problems which arise in nuclear waste remediation. 11 figs.

  19. Anatomical study of the gastrointestinal tract in free-living axis deer (Axis axis).

    Science.gov (United States)

    Pérez, W; Erdogan, S; Ungerfeld, R

    2015-02-01

    The macroscopic anatomy of the stomach and intestines of adult axis deer (Axis axis), a cervid species considered intermediate/mixed feeder, was observed and recorded. Nine adult wild axis deers of both sexes were used and studied by simple dissection. The ruminal papillae were distributed unevenly in the overall area of the inner surface of rumen and primarily were more large and abundant within the atrium. The ruminal pillars had no papillae. There was an additional ruminal pillar located between the right longitudinal and right coronary ventral pillars connected to the caudal pillar. No dorsal coronary pillars were found, and the ventral coronary pillars are connected. The reticulum was the third compartment in size, and the maximum height of the reticular crests was 1.0 mm. The Cellulae reticuli were not divided and rarely contained secondary crests. There were no Papillae unguiculiformes. The omasum was the smallest gastric compartment. The abomasum had about twelve spiral plicae, and a small pyloric torus was present. The intraruminal papillation was similar to those species that are characterized by a higher proportion of grass in their natural diet. The finding of the small reticular crests is typical for browser ruminants and was coincident with data reported for other deer. The comparative ratio of the small intestine to the large intestine was 1.69, in terms of length measurements in axis deer and appears below of the 'browser range'. We concluded that the gastrointestinal system of axis deer reflected similar morphological characteristics of the both types of ruminants: browser and grazer, and we consider it as an intermediate feeder. © 2014 Blackwell Verlag GmbH.

  20. Space camera optical axis pointing precision measurement system

    Science.gov (United States)

    Chen, Gang; Meng, Fanbo; Yang, Zijun; Guo, Yubo; Ye, Dong

    2016-01-01

    In order to realize the space camera which on satellite optical axis pointing precision measurement, a monocular vision measurement system based on object-image conjugate is established. In this system the algorithms such as object-image conjugate vision models and point by point calibration method are applied and have been verified. First, the space camera axis controller projects a laser beam to the standard screen for simulating the space camera's optical axis. The laser beam form a target point and has been captured by monocular vision camera. Then the two-dimensional coordinates of the target points on the screen are calculated by a new vision measurement model which based on a looking-up and matching table, the table has been generated by object-image conjugate algorithm through point by point calibration. Finally, compare the calculation of coordinates offered by measurement system with the theory of coordinate offered by optical axis controller, the optical axis pointing precision can be evaluated. Experimental results indicate that the absolute precision of measurement system up to 0.15mm in 2m×2m FOV. This measurement system overcome the nonlinear distortion near the edge of the FOV and can meet the requirement of space camera's optical axis high precision measurement and evaluation.

  1. 六轴联动数控齿轮加工机床加工点啮合齿面的包络逼近原理%Envelope-Approximation Theory in Manufacture for Point-Contact Tooth Surface by Six-Axis CNC Hypoid Generator

    Institute of Scientific and Technical Information of China (English)

    周凯红; 张帅

    2013-01-01

    提出了一种在六轴联动数控机床上加工点啮合齿面的新加工方法.该方法源于微分几何中通过空间曲线的Darboux-Frenet标架沿设计(理论)齿面上的一条指定接触迹线运动来描述曲面微分结构的思想,所展成的齿面与设计(理论)齿面沿指定的接触迹线有二阶切触且在接触迹线以外的区域与设计(理论)齿面之间具有指定(最小)误差,能完全控制齿面上每一个啮合点的啮合特性.利用六轴联动数控齿轮加工机床的万能运动功能,按被加工齿面预定的啮合特性确定刀具相对工件的运动.实例验证了方法的精确性和可行性.%A new generation method for point-contact tooth surface is proposed based on the six-axis movement of CNC machine.The new method is derived from the motion of Darboux-Frenet trihedron along a predesigned path of contact on the predesigned (theoretical) tooth surface.The generated tooth surface by the new method has tangency of second order with the predesigned (theoretical) surface along the predesigned path of contact and the predesigned (least) warping in regions that differ from the path of contact.This means that the new method can reliably control meshing characteristics at each contact point.In contrast,the previous method can only control meshing characteristics at a mean contact point and make correction by observing the contact-bearing condition to determine meshing characteristics at other contact points.Different from the previous CNC generation method translated from the cradle-style universal hypoid generator,the developed method directly suits the six-axis movement of CNC machine to identify the relative motion between the tool and the workpiece based on the predesigned meshing characteristics of the gear being generated.Numerical examples prove that the new manufacture method is accurate and feasible.

  2. Neospora caninum is a cause of perinatal mortality in axis deer (Axis axis).

    Science.gov (United States)

    Basso, Walter; Moré, Gastón; Quiroga, Maria Alejandra; Balducchi, Diego; Schares, Gereon; Venturini, Maria Cecilia

    2014-01-31

    Neospora caninum is a worldwide distributed protozoan that may cause neuromuscular disease in dogs and reproductive failure in domestic and wild ruminants. One axis fawn (Axis axis) and four neonates from the same deer herd died at a zoo in Argentina within a four-month period. The fawn presented with dilatation of the anal sphincter at birth and incontinence, developed weakness and ataxia and died at 14 days of age. At necropsy, a mega formation of the distal large intestine was observed. Microscopically, non-suppurative encephalitis, suppurative bronchopneumonia, fibrin necrotic enteritis and degenerative changes in the liver were observed in hematoxilin and eosin-stained tissue sections, and thick-walled N. caninum-like cysts were observed in fresh brain samples. Serologic studies for N. caninum revealed an IFAT titer of 1:6400 in the fawn and 1:25, 1:400, 1:3200 and 1:6400 in the neonates. N. caninum DNA was detected in brain samples from the fawn and from one neonate by PCR, and the parasite was isolated in vitro from the fawn' brain after passage through gerbils (Meriones unguiculatus) and gamma-interferon knock-out mice. N. caninum DNA obtained from the fawn, neonate and isolated parasites showed the same microsatellite pattern. This suggests a common infection source for both animals. The diagnosis of N. caninum infection was confirmed, suggesting its association with perinatal mortality in captive axis deer. To the best of our knowledge, this is the first report of clinical disease associated to N. caninum infection in axis deer and of isolation of the parasite from this wild ruminant species.

  3. Measurement Axis Searching Model for Terrestrial Laser Scans Registration

    Directory of Open Access Journals (Sweden)

    Shaoxing Hu

    2016-01-01

    Full Text Available Nowadays, terrestrial Lidar scans can cover rather a large area; the point densities are strongly varied because of the line-of-sight measurement principle in potential overlaps with scans taken from different viewpoints. Most of the traditional methods focus on registration algorithm and ignore searching model. Sometimes the traditional methods are directly used to align two point clouds; a large critically unsolved problem of the large biases will be created in areas distant from the overlaps while the local overlaps are often aligned well. So a novel measurement axis searching model (MASM has been proposed in this paper. The method includes four steps: (1 the principal axis fitting, (2 the measurement axis generation, (3 low-high-precision search, and (4 result generation. The principal axis gives an orientation to the point cloud; the search scope is limited by the measurement axis. The point cloud orientation can be adjusted gradually until the achievement of the global optimum using low- and high-precision search. We perform some experiments with simulated point clouds and real terrestrial laser scans. The results of simulated point clouds have shown the processing steps of our method, and the results of real terrestrial laser scans have shown the sensitivity of the approach with respect to the indoor and outdoor scenes.

  4. The Axis of Evil revisited

    CERN Document Server

    Land, K; Land, Kate; Magueijo, Joao

    2006-01-01

    In light of the three-year data release from WMAP we re-examine the evidence for the ``Axis of Evil''. We discover that previous frequentist methods are not robust with respect to the data-sets available and different treatments of the galactic plane. We identify the cause of the instability and show that this result is not a weakness of the data. This is further confirmed by exhibiting an alternative approach, Bayesian in flavour, and based on a likelihood method and the information criteria. We find strong (and sometimes decisive) evidence for the ``Axis of Evil'' in almost all renditions of the WMAP data. However some significant differences between data-sets remain, and the quantitative aspects of the result depend on the particular information criteria used.

  5. VERITAS: Versatile Triple-Axis Spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Park, Sung Il

    2006-04-15

    Korea Atomic Energy Research Institute is planning to build a cold neutron triple-axis spectrometer at HANARO, the 30 MW research reactor. The spectrometer is expected to be completed in 2008 with the following configuration from the upstream to the downstream. Guide Supermirror m = 2, In-pile Straight Section, {approx} 5 m Curved Guide, {approx} 26 m w/ R 1500 m Straight Guide before the Instrument, {approx} 40 m Filters PG and Be Neutron Velocity Selector (Future) Monochromators Vertically Focusing Monochromators PG(002) and Heusler(111) Doubly Focusing Monochromators (Future) Monochromator-Sample Distance 2 m Collimation C1 Soller Collimators, 20', 40' 80'Beam Height at the Sample Table 1.5 m Sample-Analyzer Distance 1.0 m Collimation C2 Soller Collimators, 20', 40', 80' Radial Collimator Analyzers Horizontally Focusing Analyzers w/ Fixed Vertical Focusing PG(002) and Heusler(111) Analyzer-Detector Distance 0.5 m Detectors 5 cm Tube Detector 25 cm wide Position Sensitive Detector Once completed, the neutron flux at sample is expected to surpass that of SPINS at NCNR, making this instrument one of the most powerful 2nd generation cold neutron triple-axis spectrometers in the world.

  6. Kinematical analysis of 5-axis corner smoothing for transitions between linear (G1) blocks

    OpenAIRE

    Beudaert, Xavier; Lavernhe, Sylvain; Tournier, Christophe

    2012-01-01

    5-axis high speed machine tools are widely used in industry. The axis movements are generated by the Computer Numerical Controller (CNC) which has to transform the part program into a sequence of axis setpoints. Most of the time, the tool path is described with linear segments (G1) which lead to tangency discontinuities between blocks. With acceleration and jerk limitations, these discontinuities will induce a zero feedrate and thus surface marks and an increase in machining time. The aim of ...

  7. Five-axis rough machining for impellers

    Institute of Scientific and Technical Information of China (English)

    Ruolong QI; Weijun LIU; Hongyou BIAN; Lun LI

    2009-01-01

    The most important components used in aero-space, ships, and automobiles are designed with free form surfaces. An impeller is one of the most important components that is difficult to machine because of its twisted blades. Rough machining is recognized as the most crucial procedure influencing machining efficiency and is critical for the finishing process. An integrated rough machining course with detailed algorithms is presented in this paper. An algorithm for determining the minimum distance between two surfaces is applied to estimate the tool size. The space between two blades that will be cleared from the roughcast is divided to generate CC points. The tool axis vector is confirmed based on flank milling using a simple method that could eliminate global interference between the tool and the blades. The result proves that the machining methodology presented in this paper is useful and successful.

  8. Critique of the two-fold measure of prediction success for ratios: application for the assessment of drug-drug interactions.

    Science.gov (United States)

    Guest, Eleanor J; Aarons, Leon; Houston, J Brian; Rostami-Hodjegan, Amin; Galetin, Aleksandra

    2011-02-01

    Current assessment of drug-drug interaction (DDI) prediction success is based on whether predictions fall within a two-fold range of the observed data. This strategy results in a potential bias toward successful prediction at lower interaction levels [ratio of the area under the concentration-time profile (AUC) in the presence of inhibitor/inducer compared with control is assessment of different DDI prediction algorithms if databases contain large proportion of interactions in this lower range. Therefore, the current study proposes an alternative method to assess prediction success with a variable prediction margin dependent on the particular AUC ratio. The method is applicable for assessment of both induction and inhibition-related algorithms. The inclusion of variability into this predictive measure is also considered using midazolam as a case study. Comparison of the traditional two-fold and the new predictive method was performed on a subset of midazolam DDIs collated from previous databases; in each case, DDIs were predicted using the dynamic model in Simcyp simulator. A 21% reduction in prediction accuracy was evident using the new predictive measure, in particular at the level of no/weak interaction (AUC ratio assessed via the new predictive measure. Thus, the study proposes a more logical method for the assessment of prediction success and its application for induction and inhibition DDIs.

  9. Local Auxin Sources Orient the Apical-Basal Axis in Arabidopsis Embryos

    NARCIS (Netherlands)

    Robert, H.S.; Grones, P.; Stepanova, A.N.; Robles, L.M.; Lokerse, A.S.; Alonso, J.M.; Weijers, D.; Friml, J.

    2013-01-01

    Establishment of the embryonic axis foreshadows the main body axis of adults both in plants and in animals, but underlying mechanisms are considered distinct. Plants utilize directional, cell-to-cell transport of the growth hormone auxin [1 and 2] to generate an asymmetric auxin response that specif

  10. Three-axis force actuator for a magnetic bearing

    Science.gov (United States)

    Gondhalekar, Vijay (Inventor)

    1998-01-01

    This invention features a three-axis force actuator that axially, radially and rotatably supports a bearing member for frictionless rotation about an axis of rotation generally coincident with a Z-axis. Also featured is a magnetic bearing having such an actuator. The actuator includes an inner member, a magnetic member and a pole assembly having a ring member and four pole extending therefrom. The poles are equi-angular spaced from each other and radially spaced about the Z-axis. The inner member extends along the Z-axis and is a highly magnetic permeable material. The magnetic member is formed about the inner member outer surface, extends along the Z-axis and is configured so one magnetic pole polarity is located at its outer surface and the other polarity pole is located at its inner surface. Preferably, the magnetic member is a radially magnetized permanent magnet. The inner surface of the ring member is magnetically coupled to the magnetic member and a face of each pole is coupled to the bearing member. The magnetic member, the pole assembly, the inner member and the bearing member cooperate to generate a magnetic field that radially and rotatably supports a rotating member secured to the bearing member. The actuator further includes a plurality of electromagnetic coils. Preferably, a coil is formed about each pole and at least 2 coils are formed about the inner member. When energized, the electromagnetic coils generate a modulated magnetic field that stabilizes the rotating member in the desired operational position.

  11. Magnetic axis alignment and the Poisson alignment reference system

    Science.gov (United States)

    Griffith, Lee V.; Schenz, Richard F.; Sommargren, Gary E.

    1989-01-01

    Three distinct metrological operations are necessary to align a free-electron laser (FEL): the magnetic axis must be located, a straight line reference (SLR) must be generated, and the magnetic axis must be related to the SLR. This paper begins with a review of the motivation for developing an alignment system that will assure better than 100 micrometer accuracy in the alignment of the magnetic axis throughout an FEL. The paper describes techniques for identifying the magnetic axis of solenoids, quadrupoles, and wiggler poles. Propagation of a laser beam is described to the extent of revealing sources of nonlinearity in the beam. Development and use of the Poisson line, a diffraction effect, is described in detail. Spheres in a large-diameter laser beam create Poisson lines and thus provide a necessary mechanism for gauging between the magnetic axis and the SLR. Procedures for installing FEL components and calibrating alignment fiducials to the magnetic axes of the components are also described. An error budget shows that the Poisson alignment reference system will make it possible to meet the alignment tolerances for an FEL.

  12. Creating a Multi-axis Machining Postprocessor

    Directory of Open Access Journals (Sweden)

    Petr Vavruška

    2012-01-01

    Full Text Available This paper focuses on the postprocessor creation process. When using standard commercially available postprocessors it is often very difficult to modify its internal source code, and it is a very complex process, in many cases even impossible, to implement the newly-developed functions. It is therefore very important to have a method for creating a postprocessor for any CAM system, which allows CL data (Cutter Location data to be generated to a separate text file. The goal of our work is to verify the proposed method for creating a postprocessor. Postprocessor functions for multi-axis machiningare dealt with in this work. A file with CL data must be translated by the postprocessor into an NC program that has been customized for a specific production machine and its control system. The postprocessor is therefore verified by applications for machining free-form surfaces of complex parts, and by executing the NC programs that are generated on real machine tools. This is also presented here.

  13. Antenna Axis Offset Estimation from VLBI

    Science.gov (United States)

    Kurdubov, Sergey; Skurikhina, Elena

    2010-01-01

    The antenna axis offsets were estimated from global solutions and single sessions. We have built a set of global solutions from R1 and R4 sessions and from the sets of sessions between SVETLOE repairs. We compared our estimates with local survey data for the stations of the QUASAR network. Svetloe station axis offset values have changed after repairs. For non-global networks, the axis offset value of a single station can significantly affect the EOP estimations.

  14. Discrete Scale Axis Representations for 3D Geometry

    OpenAIRE

    Miklos, Balint; Giesen, Joachim; Pauly, Mark

    2010-01-01

    This paper addresses the fundamental problem of computing stable medial representations of 3D shapes. We propose a spatially adaptive classification of geometric features that yields a robust algorithm for generating medial representations at different levels of abstraction. The recently introduced continuous scale axis transform serves as the mathematical foundation of our algorithm. We show how geometric and topological properties of the continuous setting carry over to discrete shape repre...

  15. A numerical method of tracing a vortical axis along local topological axis line

    Science.gov (United States)

    Nakayama, Katsuyuki; Hasegawa, Hideki

    2016-06-01

    A new numerical method is presented to trace or identify a vortical axis in flow, which is based on Galilean invariant flow topology. We focus on the local flow topology specified by the eigenvalues and eigenvectors of the velocity gradient tensor, and extract the axis component from its flow trajectory. Eigen-vortical-axis line is defined from the eigenvector of the real eigenvalue of the velocity gradient tensor where the tensor has the conjugate complex eigenvalues. This numerical method integrates the eigen-vortical-axis line and traces a vortical axis in terms of the invariant flow topology, which enables to investigate the feature of the topology-based vortical axis.

  16. Transverse beam motion on the second axis of the dual axis radiographic hydrodynamic test facility

    Energy Technology Data Exchange (ETDEWEB)

    Caporaso, G J; Chen, Y J; Fawley, W M; Paul, A C

    1999-03-23

    The accelerator on the second-axis of the Dual-Axis Radiographic Hydrodynamic Test (DARHT-II) facility will generate a 20 MeV, 2-4 kA, 2 µs long electron beam with an energy variation {<=} ± 0.5%. Four short current pulses with various lengths will be selected out of this 2 µs long current pulse and delivered to an x-ray converter target. The DARHT-II radiographic resolution requires these electron pulses to be focused to sub-millimeter spots on Bremsstrahlung targets with peak-to-peak transverse beam motion less than a few hundred microns. We have modeled the transverse beam motion, including the beam breakup instability, corkscrew motion, transverse resistive wall instability and beam induced transverse deflection in the kicker system, from the DARHT-II injector exit to the x-ray converter target. Simulations show that the transverse motion at the x-ray converters satisfies the DARHT-II radiographic requirements.

  17. Acute injuries of the axis vertebra

    Energy Technology Data Exchange (ETDEWEB)

    Burke, J.T. (United General Hospital, Sedro Woolley, WA (USA)); Harris, J.H. (Texas Univ., Houston, TX (USA). Dept. of Radiology)

    1989-08-01

    A retrospective analysis of 165 patients admitted to Hermann Hospital with acute injuries of the axis vertebra revealed 68 (41%) dens fractures, 62 (38%) cases of traumatic spondylolisthesis ('hangman's' fracture), 21 (13%) extension teardrop fractures, 10 (6%) hyperextension dislocations, and 2 (1.0%) fractures each of the laminae and spinous processes. Of the axis injuries 31 (18%) were limited to the axis body alone. Of these, 21 (61%) were hyperextension teardrop fractures and 10 (32%) were hyperextension dislocations. Axis injuries were associated with acute injuries of other cervical vertebrae in 14 (8%) of the patients. (orig./GDG).

  18. A News Recommendation Method Based on Two-Fold Clustering%基于二次聚类的新闻推荐方法

    Institute of Scientific and Technical Information of China (English)

    古万荣; 董守斌; 何锦潮; 曾之肇

    2014-01-01

    Due to fast update of news , the clustering-based preprocessing is usually needed when the news is recom-mended to users .However , some traditional clustering methods are too complicated while others rely on iterative ini -tial value , none of which can be accurately and effectively applied to news recommendation .Considering the above issues, we propose a news recommendation method based on two-fold clustering.In this method, a density clustering of random sample data is conducted .Based on the cluster number and initial cluster center of the density clustering , a fast two-fold clustering of all the news to be recommended is performed .Then, the news recommendation is realized by combining such factors as fashionability and popularity .The proposed method can cluster relevant news without too much computation cost , and it can calculate parameters by means of parameter estimation .Experimental results show that the proposed method is superior to other news recommendation methods in terms of diversity and accuracy .%由于新闻更新快,对用户进行新闻推荐往往需要进行聚类预处理,而传统方法要么复杂度过高,要么依赖于迭代初值,都不能准确而高效地应用于新闻推荐中。针对以上问题,文中提出了一个基于二次聚类的新闻推荐方法,对随机抽样数据进行密度聚类,基于该样本密度聚类的簇数和初始簇心进行所有待推荐新闻的二次快速聚类,并结合时新性、新闻热度等因素实现新闻推荐。文中方法可以将相关新闻聚集在一起,同时又不导致过高的运算开销,并通过参数估计方法计算各因素参数。实验结果表明,与其他新闻推荐方法相比,文中方法具有较好的推荐多样性和推荐准确度。

  19. Significant flux trapping in single grain GdBCO bulk superconductor under off-axis field cooled magnetization

    Science.gov (United States)

    Li, Zhi; Ida, Tetsuya; Miki, Motohiro; Teshima, Hidekazu; Morita, Mitsuru; Izumi, Mitsuru

    2017-03-01

    A single grain bulk high-temperature superconductor (HTS) exhibits intensified flux trapping performance upon field cooled magnetization. The world record of trapped flux is 17.6 T achieved by using stacked two-fold GdBCO bulks. However, the majority of magnetization studies focused on the magnetization along the crystallographic c-axis. In the present study, we clarify the flux trapping performance under field cooled magnetization using an off-axis magnetic field with respect to the c-axis. The results show that the trapped flux is almost polarized along the applied field as expected. This tendency remains up to a high off-axis angle θ around 60°. It is worth mentioning that, with θ of 30°, the maximum trapped flux component B // max parallel to the c-axis significantly remains more than 96% of 1.6 T which occurs under on-axis magnetization. Meanwhile, the angular dependence of the c-axis parallel component exhibits that observed flux density is higher than that expected from 1.6 cosθ. In addition, to visualize the flux line upon magnetization at θ of 90°, we successfully demonstrate the continuous flux line trace using steel wires; different trapped flux behaviour appears when applied field penetrates the bulk through the growth sectors centre and along the growth sector boundary, respectively. We interpret these results may come from the microstructure as a result of melt growth. It is highly emphasized that the off-axis magnetization with the finite inclination angle is quite useful for introducing into the design of HTS applications.

  20. Short-axis epicardial volume change is a measure of cardiac left ventricular short-axis function, which is independent of myocardial wall thickness.

    Science.gov (United States)

    Ugander, Martin; Carlsson, Marcus; Arheden, Håkan

    2010-02-01

    Fractional shortening (FS) by echocardiography is considered to represent the short-axis contribution to the stroke volume (SV), also called short-axis function. However, FS is mathematically coupled to the amount of myocardium, since it rearranges during atrioventricular plane displacement (AVPD). The SV is the sum of the volumes generated by 1) reduction in outer volume of the heart, and 2) inner AVPD. The long-axis contribution to the SV is generated by AVPD, and thus the short-axis contribution is the remaining outer volume change of the heart, which should be unrelated to myocardial wall thickness. We hypothesized that both endocardial and midwall shortening indexed to SV are dependent on myocardial wall thickness, whereas epicardial volume change (EVC) indexed to SV is not. Twelve healthy volunteers (normals), 12 athletes, and 12 patients with dilated cardiomyopathy (ejection fraction EVC was defined as SV minus long-axis function. Endocardial and midwall shortening were measured in a midventricular short-axis slice. Endocardial shortening/SV and midwall shortening/SV both varied in relation to end-diastolic myocardial wall thickness (R(2) = 0.16, P = 0.008 and R(2) = 0.14, P = 0.012, respectively), whereas EVC/SV did not (R(2) = 0.00, P = 0.37). FS is dependent on myocardial wall thickness, whereas EVC is not and therefore represents true short-axis function. This is not surprising considering that FS is mainly caused by rearrangement of myocardium secondary to long-axis function. FS is therefore not synonymous with short-axis function.

  1. The Long-term Risk of Upper-extremity Lymphedema is Two-fold Higher in Breast Cancer Patients than in Melanoma Patients

    Science.gov (United States)

    Voss, Rachel K.; Cromwell, Kate D.; Chiang, Yi-Ju; Armer, Jane M.; Ross, Merrick I.; Lee, Jeffrey E.; Gershenwald, Jeffrey E.; Stewart, Bob R.; Shaitelman, Simona F.; Cormier, Janice N.

    2015-01-01

    Background and Objectives We assessed the cumulative incidence, symptoms, and risk factors for upper-extremity lymphedema in breast cancer and melanoma patients undergoing sentinel lymph node biopsy or axillary lymph node dissection. Methods Patients were recruited preoperatively (time 0) and assessed at 6, 12, and 18 months postoperatively. Limb volume change (LVC) was measured by perometry. Lymphedema was categorized as none, mild (LVC 5–9.9%), or moderate/severe (LVC≥10%). Symptoms were assessed with a validated lymphedema instrument. Longitudinal logistic regression analyses were conducted to identify risk factors associated with moderate/severe lymphedema. Results Among 205 breast cancer and 144 melanoma patients, the cumulative incidence of moderate/severe lymphedema at 18 months was 36.5% and 35.0, respectively. However, in adjusted analyses, factors associated with moderate/severe lymphedema were breast cancer (OR 2.0, p=0.03), body mass index ≥30 kg/m2 (OR 1.6, p=0.04), greater number of lymph nodes removed (OR 1.05, pLymphedema incidence increased over time in both cohorts. However, the adjusted risk of moderate/severe lymphedema was two-fold higher in breast cancer patients. These results may be attributed to surgical treatment of the primary tumor in the breast and more frequent use of radiation. PMID:26477877

  2. Innovative Design of Vertical Axis Wind Turbine

    DEFF Research Database (Denmark)

    Chougule, Prasad

    2013-01-01

    The wind turbines can be classified as: i) Horizontal axis wind turbines (HAWT), and ii) Vertical axis wind turbines (VAWT). The HAWT is fully developed and the size is growing higher. Whereas, the VAWT is not developed because of the less efficiency and vibration issues of big structure. However...

  3. Basinal seamounts and seamount chains of the Central Indian Ocean: Probable near-axis origin from a fast-spreading ridge

    Digital Repository Service at National Institute of Oceanography (India)

    Mukhopadhyay, R.; Batiza, R.

    -axis seamount generation may be a result of fast-spreading rate rather than a peculiarity of the present pacific spreading ridges. In fact, the results of several recent studies, taken together, suggest that the style of axis/near-axis seamount volcanism varies...

  4. 2002–2012: 10 Years of Research Progress in Horizontal-Axis Marine Current Turbines

    Directory of Open Access Journals (Sweden)

    Kai-Wern Ng

    2013-03-01

    Full Text Available Research in marine current energy, including tidal and ocean currents, has undergone significant growth in the past decade. The horizontal-axis marine current turbine is one of the machines used to harness marine current energy, which appears to be the most technologically and economically viable one at this stage. A number of large-scale marine current turbines rated at more than 1 MW have been deployed around the World. Parallel to the development of industry, academic research on horizontal-axis marine current turbines has also shown positive growth. This paper reviews previous research on horizontal-axis marine current turbines and provides a concise overview for future researchers who might be interested in horizontal-axis marine current turbines. The review covers several main aspects, such as: energy assessment, turbine design, wakes, generators, novel modifications and environmental impact. Future trends for research on horizontal-axis marine current turbines are also discussed.

  5. Analisis Semiotika Makna Pesan pada Iklan Axis Versi “Iritologi – Menatap Masa Depan”

    Directory of Open Access Journals (Sweden)

    Puri Sulistiyawati

    2016-02-01

    the habits of teenagers  use a social media. From visual ads displayed reinforce the message that this Axis products is targeting the youth as target audience, teenagers or students are consumers who crave products with good quality but at an affordable price. Although targeting teenagers, but in Axis target market remains targeting all circles. The Setting or background on the ads are displayed also as a representation that  Axis can be reached all circles of society, especially the lower middle class. The myth meaning in Axis adv is implied a specific scene. Generally these ads is convey that selfie and social media as part of people's lives, especially the younger generation wich use it to interact and shows their existence to community. Through the uploaded photos on social media, the audience represents feelings and activities that are doing. So, It’s triggers the requirements for fluent and economic network communication. Keywords: advertisement, Axis, myth, semiotic

  6. Identification of Kinematic Errors of Five-axis Machine Tool Trunnion Axis from Finished Test Piece

    Institute of Scientific and Technical Information of China (English)

    ZHANG Ya; FU Jianzhong; CHEN Zichen

    2014-01-01

    Compared with the traditional non-cutting measurement, machining tests can more accurately reflect the kinematic errors of five-axis machine tools in the actual machining process for the users. However, measurement and calculation of the machining tests in the literature are quite difficult and time-consuming. A new method of the machining tests for the trunnion axis of five-axis machine tool is proposed. Firstly, a simple mathematical model of the cradle-type five-axis machine tool was established by optimizing the coordinate system settings based on robot kinematics. Then, the machining tests based on error-sensitive directions were proposed to identify the kinematic errors of the trunnion axis of cradle-type five-axis machine tool. By adopting the error-sensitive vectors in the matrix calculation, the functional relationship equations between the machining errors of the test piece in the error-sensitive directions and the kinematic errors of C-axis and A-axis of five-axis machine tool rotary table was established based on the model of the kinematic errors. According to our previous work, the kinematic errors of C-axis can be treated as the known quantities, and the kinematic errors of A-axis can be obtained from the equations. This method was tested in Mikron UCP600 vertical machining center. The machining errors in the error-sensitive directions can be obtained by CMM inspection from the finished test piece to identify the kinematic errors of five-axis machine tool trunnion axis. Experimental results demonstrated that the proposed method can reduce the complexity, cost, and the time consumed substantially, and has a wider applicability. This paper proposes a new method of the machining tests for the trunnion axis of five-axis machine tool.

  7. 3Dwheel: 3-axis low-noise, high-bandwidth attitude actuation from a single momentum wheel using magnetic bearings.

    OpenAIRE

    Seddon, Jon; Pechev, Alexandre

    2009-01-01

    This paper proposes a new concept for attitude actuation for small satellites that uses active magnetic bearings to support and tilt a spinning rotor to provide 3-axis attitude control of the satellite using a single actuator. A controlled 3D motion in the spinning rotor provides a conventional torque output about the momentum axis and a gyroscopic torque output about any direction in the plane normal to the spinning axis. Therefore, a single tilting momentum-wheel can generate torque along t...

  8. Analysis of transitions at two-fold redundant sites in mammalian genomes. Transition redundant approach-to-equilibrium (TREx distance metrics

    Directory of Open Access Journals (Sweden)

    Liberles David A

    2006-03-01

    Full Text Available Abstract Background The exchange of nucleotides at synonymous sites in a gene encoding a protein is believed to have little impact on the fitness of a host organism. This should be especially true for synonymous transitions, where a pyrimidine nucleotide is replaced by another pyrimidine, or a purine is replaced by another purine. This suggests that transition redundant exchange (TREx processes at the third position of conserved two-fold codon systems might offer the best approximation for a neutral molecular clock, serving to examine, within coding regions, theories that require neutrality, determine whether transition rate constants differ within genes in a single lineage, and correlate dates of events recorded in genomes with dates in the geological and paleontological records. To date, TREx analysis of the yeast genome has recognized correlated duplications that established a new metabolic strategies in fungi, and supported analyses of functional change in aromatases in pigs. TREx dating has limitations, however. Multiple transitions at synonymous sites may cause equilibration and loss of information. Further, to be useful to correlate events in the genomic record, different genes within a genome must suffer transitions at similar rates. Results A formalism to analyze divergence at two fold redundant codon systems is presented. This formalism exploits two-state approach-to-equilibrium kinetics from chemistry. This formalism captures, in a single equation, the possibility of multiple substitutions at individual sites, avoiding any need to "correct" for these. The formalism also connects specific rate constants for transitions to specific approximations in an underlying evolutionary model, including assumptions that transition rate constants are invariant at different sites, in different genes, in different lineages, and at different times. Therefore, the formalism supports analyses that evaluate these approximations. Transitions at synonymous

  9. Downwind rotor horizontal axis wind turbine noise prediction

    Science.gov (United States)

    Metzger, F. B.; Klatte, R. J.

    1981-01-01

    NASA and industry are currently cooperating in the conduct of extensive experimental and analytical studies to understand and predict the noise of large, horizontal axis wind turbines. This effort consists of (1) obtaining high quality noise data under well controlled and documented test conditions, (2) establishing the annoyance criteria for impulse noise of the type generated by horizontal axis wind turbines with rotors downwind of the support tower, (3) defining the wake characteristics downwind of the axial location of the plane of rotation, (4) comparing predictions with measurements made by use of wake data, and (5) comparing predictions with annoyance criteria. The status of work by Hamilton Standard in the above areas which was done in support of the cooperative NASA and industry studies is briefly summarized.

  10. Dual Axis Light Sensor for Tracking Sun

    Science.gov (United States)

    Shibata, Miki; Tambo, Toyokazu

    We have developed convenient light sensors to control a platform of solar cell panel. Dual axis light sensor in the present paper has structure of 5 PD (photodiode) light sensor which is composed of 5 photodiodes attached on a frustum of pyramid(1). Light source can be captured in front of the sensor by rotating the X and Y axis as decreasing the output deviation between two pairs of outside photodiodes. We here report the mechanism of sun tacking using the dual axis 5 PD light sensor and the fundamental results performed in the dark room.

  11. Design and dynamic analysis of single-axis integrated inertia measurement device

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The structure and measurement theory of a single-axis integrated inertia measurement device are discussed in this paper.The acceleration and angle velocity can be detected by the proposed sensor at the same time.The kinetic model of the device is also established.In addition,the signal generation of the single-axis integrated inertiameasurement device is analyzed and simulated.The results of the model are consistent with simulation result.

  12. Axis of Zodiacal light Near Tropic Cancer

    CERN Document Server

    Nawar, S; Mikhail, J S; Morcos, A B; Ibrahim, Alhassan I

    2014-01-01

    The axis of zodiacal lights have been obtained in blue and yellow colors using photoelectric observations of zodiacal light. These observations have been carried out at Abu Simbel Site in Egypt, in October 1975. This site lies too near to the tropic of Cancer, at which the axis of the zodiacal light cone perpendiculars to the horizon. The results show that the plane of the zodiacal light is inclined to the normal by 1.59 degrees in blue color and 1.18 degrees in yellow color. This means that there is a slight variation in zodiacal light axis with wavelength, and the axis almost coincide with the ecliptic. The present results for blue color can be considered as the first one in the world near the tropic of Cancer.

  13. Spinning pipe gas lens aberrations along the axis and in the boundary layer

    CSIR Research Space (South Africa)

    Mafusire, C

    2013-11-01

    Full Text Available laser beam propagating along the pipe’s axis – a spinning pipe gas lens. However, the interaction of the heated and cooler air generates local density fluctuations which generate aberrations on the laser beam wavefront. We present results...

  14. Electrical-Discharge Machining With Additional Axis

    Science.gov (United States)

    Malinzak, Roger M.; Booth, Gary N.

    1991-01-01

    Proposed electrical-discharge-machining (EDM) apparatus uses moveable vertical wire as electrode. Wire positionable horizontally along one axis as it slides vertically past workpiece. Workpiece indexed in rotation about horizontal axis. Because of symmetry of parts, process used to make two such parts at a time by defining boundary between them. Advantages: cost of material reduced, imparts less residual stress to workpiece, and less time spent machining each part when parts produced in such symmetrical pairs.

  15. Motor/generator

    Science.gov (United States)

    Hickam, Christopher Dale

    2008-05-13

    A motor/generator is provided for connecting between a transmission input shaft and an output shaft of a prime mover. The motor/generator may include a motor/generator housing, a stator mounted to the motor/generator housing, a rotor mounted at least partially within the motor/generator housing and rotatable about a rotor rotation axis, and a transmission-shaft coupler drivingly coupled to the rotor. The transmission-shaft coupler may include a clamp, which may include a base attached to the rotor and a plurality of adjustable jaws.

  16. Axis Offset Estimation of VLBI Telescopes

    Science.gov (United States)

    Krásná, Hana; Nickola, Marisa; Böhm, Johannes

    2014-12-01

    Axis offset models have to be applied for VLBI telescopes with pointing axes which do not intersect. In this work, we estimated the axis offsets for VLBI antennas in a global adjustment of suitable IVS 24-hour sessions (1984.0-2014.0) with the Vienna VLBI Software (VieVS). In particular, we focused on the two radio telescopes of the Hartebeesthoek Radio Astronomy Observatory (HartRAO) in South Africa. For the older 26-m telescope we compared the estimated axis offset values before (6699.2 ± 0.5 mm) and after (6707.3 ± 0.8 mm) the bearing repair in 2010. A comparison with axis offset estimates from other geodetic techniques, such as GNSS or conventional local survey, was made. The estimated axis offset for the newer 15-m telescope (1495.0 ± 3.4 mm) agrees with the estimated value from the GPS survey in 2007. Furthermore, we assessed the influence of differences in the axis offsets on the estimated geodetic parameters, such as station coordinates or Earth Orientation Parameters.

  17. Sex differences in the HPA axis.

    Science.gov (United States)

    Goel, Nirupa; Workman, Joanna L; Lee, Tiffany T; Innala, Leyla; Viau, Victor

    2014-07-01

    The hypothalamic-pituitary-adrenal (HPA) axis is a major component of the systems that respond to stress, by coordinating the neuroendocrine and autonomic responses. Tightly controlled regulation of HPA responses is critical for maintaining mental and physical health, as hyper- and hypo-activity have been linked to disease states. A long history of research has revealed sex differences in numerous components of the HPA stress system and its responses, which may partially form the basis for sex disparities in disease development. Despite this, many studies use male subjects exclusively, while fewer reports involve females or provide direct sex comparisons. The purpose of this article is to present sex comparisons in the functional and molecular aspects of the HPA axis, through various phases of activity, including basal, acute stress, and chronic stress conditions. The HPA axis in females initiates more rapidly and produces a greater output of stress hormones. This review focuses on the interactions between the gonadal hormone system and the HPA axis as the key mediators of these sex differences, whereby androgens increase and estrogens decrease HPA activity in adulthood. In addition to the effects of gonadal hormones on the adult response, morphological impacts of hormone exposure during development are also involved in mediating sex differences. Additional systems impinging on the HPA axis that contribute to sex differences include the monoamine neurotransmitters norepinephrine and serotonin. Diverse signals originating from the brain and periphery are integrated to determine the level of HPA axis activity, and these signals are, in many cases, sex-specific.

  18. Actuator assembly including a single axis of rotation locking member

    Science.gov (United States)

    Quitmeyer, James N.; Benson, Dwayne M.; Geck, Kellan P.

    2009-12-08

    An actuator assembly including an actuator housing assembly and a single axis of rotation locking member fixedly attached to a portion of the actuator housing assembly and an external mounting structure. The single axis of rotation locking member restricting rotational movement of the actuator housing assembly about at least one axis. The single axis of rotation locking member is coupled at a first end to the actuator housing assembly about a Y axis and at a 90.degree. angle to an X and Z axis providing rotation of the actuator housing assembly about the Y axis. The single axis of rotation locking member is coupled at a second end to a mounting structure, and more particularly a mounting pin, about an X axis and at a 90.degree. angle to a Y and Z axis providing rotation of the actuator housing assembly about the X axis. The actuator assembly is thereby restricted from rotation about the Z axis.

  19. Design and Analysis of Vertical Axis Savonius Wind Turbine

    OpenAIRE

    2016-01-01

    This paper presents the design and analysis of vertical axis Savonius wind turbine to generate electrical energy from wind energy. The Savonius rotor was designed with the rotor diameter of 2 m and the rotor height of 4 m. The 3D model of Savonius rotor blade was made by utilizing SolidWorks software. Computational Fluid Dynamics (CFD)analysis and structural Finite Element Analysis are presented in this paper. CFD analysis was done to obtain the pressure difference between concave and conv...

  20. On the off-axis tensile test for unidirectional composites

    Science.gov (United States)

    Nemeth, M. P.; Herakovich, C. T.; Post, D.

    1982-01-01

    The off axis tensile test was examined experimentally to obtain actual displacement fields over the surface of graphite polyimide coupon specimens. The experimental results were compared with approximate analytical solutions and generated finite element results. An optical method of high sensitivity moire interferometry was used to determine the actual displacements to high precision. The approximate analytical solution and the finite element results compare very favorably with the measured centerline displacements in the test section, and the finite element displacement fields provide excellent agreement with the moire displacements throughout the specimen. A 15 degree fiber orientation and coupon aspect ratios of 5 and 15 are presented.

  1. Design and Analysis of Vertical Axis Savonius Wind Turbine

    Directory of Open Access Journals (Sweden)

    S. Jagadish Venkata Sai

    2016-04-01

    Full Text Available This paper presents the design and analysis of vertical axis Savonius wind turbine to generate electrical energy from wind energy. The Savonius rotor was designed with the rotor diameter of 2 m and the rotor height of 4 m. The 3D model of Savonius rotor blade was made by utilizing SolidWorks software. Computational Fluid Dynamics (CFDanalysis and structural Finite Element Analysis are presented in this paper. CFD analysis was done to obtain the pressure difference between concave and convex surface of the rotor blade and structural FEA was done to obtain the structural response of blade.

  2. Neuropeptides and the microbiota-gut-brain axis.

    Science.gov (United States)

    Holzer, Peter; Farzi, Aitak

    2014-01-01

    Neuropeptides are important mediators both within the nervous system and between neurons and other cell types. Neuropeptides such as substance P, calcitonin gene-related peptide and neuropeptide Y (NPY), vasoactive intestinal polypeptide, somatostatin and corticotropin-releasing factor are also likely to play a role in the bidirectional gut-brain communication. In this capacity they may influence the activity of the gastrointestinal microbiota and its interaction with the gut-brain axis. Current efforts in elucidating the implication of neuropeptides in the microbiota-gut-brain axis address four information carriers from the gut to the brain (vagal and spinal afferent neurons; immune mediators such as cytokines; gut hormones; gut microbiota-derived signalling molecules) and four information carriers from the central nervous system to the gut (sympathetic efferent neurons; parasympathetic efferent neurons; neuroendocrine factors involving the adrenal medulla; neuroendocrine factors involving the adrenal cortex). Apart from operating as neurotransmitters, many biologically active peptides also function as gut hormones. Given that neuropeptides and gut hormones target the same cell membrane receptors (typically G protein-coupled receptors), the two messenger roles often converge in the same or similar biological implications. This is exemplified by NPY and peptide YY (PYY), two members of the PP-fold peptide family. While PYY is almost exclusively expressed by enteroendocrine cells, NPY is found at all levels of the gut-brain and brain-gut axis. The function of PYY-releasing enteroendocrine cells is directly influenced by short chain fatty acids generated by the intestinal microbiota from indigestible fibre, while NPY may control the impact of the gut microbiota on inflammatory processes, pain, brain function and behaviour. Although the impact of neuropeptides on the interaction between the gut microbiota and brain awaits to be analysed, biologically active peptides

  3. Aeroelastically coupled blades for vertical axis wind turbines

    Science.gov (United States)

    Paquette, Joshua; Barone, Matthew F.

    2016-02-23

    Various technologies described herein pertain to a vertical axis wind turbine blade configured to rotate about a rotation axis. The vertical axis wind turbine blade includes at least an attachment segment, a rear swept segment, and optionally, a forward swept segment. The attachment segment is contiguous with the forward swept segment, and the forward swept segment is contiguous with the rear swept segment. The attachment segment includes a first portion of a centroid axis, the forward swept segment includes a second portion of the centroid axis, and the rear swept segment includes a third portion of the centroid axis. The second portion of the centroid axis is angularly displaced ahead of the first portion of the centroid axis and the third portion of the centroid axis is angularly displaced behind the first portion of the centroid axis in the direction of rotation about the rotation axis.

  4. Design Of Rotor Blade For Vertical Axis Wind Turbine Using Double Aerofoil

    DEFF Research Database (Denmark)

    Chougule, Prasad; Ratkovich, Nicolas Rios; Kirkegaard, Poul Henning

    Nowadays, small vertical axis wind turbines are receiving more attention compared to horizontal wind turbines due to their suitability in urban use because they generate less noise, have bird free turbines and lower cost. There is few vertical axis wind turbines design with good power curve....... However, the efficiency of power extraction has not been improved. Therefore, an attempt has been made to utilize high lift technology in practice for vertical axis wind turbines in order to improve power efficiency. High lift is obtained by double aerofoil elements mainly used in aeroplane wing design....... In this current work two aerofoils are used to design a rotor blade for a vertical axis wind turbine to improve the power efficiency on the rotor. Double aerofoil blade design consists of a main aerofoil and a slat aerofoil. The parameters related to position and orientation of the slat aerofoil with respect...

  5. Design Of Rotor Blade For Vertical Axis Wind Turbine Using Double Aerofoil

    DEFF Research Database (Denmark)

    Chougule, Prasad; Ratkovich, Nicolas Rios; Kirkegaard, Poul Henning;

    Nowadays, small vertical axis wind turbines are receiving more attention compared to horizontal wind turbines due to their suitability in urban use because they generate less noise, have bird free turbines and lower cost. There is few vertical axis wind turbines design with good power curve....... However, the efficiency of power extraction has not been improved. Therefore, an attempt has been made to utilize high lift technology in practice for vertical axis wind turbines in order to improve power efficiency. High lift is obtained by double aerofoil elements mainly used in aeroplane wing design....... In this current work two aerofoils are used to design a rotor blade for a vertical axis wind turbine to improve the power efficiency on the rotor. Double aerofoil blade design consists of a main aerofoil and a slat aerofoil. The parameters related to position and orientation of the slat aerofoil with respect...

  6. Diffuser Augmented Horizontal Axis Tidal Current Turbines

    Directory of Open Access Journals (Sweden)

    Nasir Mehmood

    2012-09-01

    Full Text Available The renewal energy technologies are increasingly popular to ensure future energy sustenance and address environmental issues. The tides are enormous and consistent untapped resource of renewable energy. The growing interest in exploring tidal energy has compelling reasons such as security and diversity of supply, intermittent but predictable and limited social and environmental impacts. The tidal energy industry is undergoing an increasing shift towards diffuser augmented turbines. The reason is the higher power output of diffuser augmented turbines compared to conventional open turbines. The purpose of this study is to present a comprehensive review of diffuser augmented horizontal axis tidal current turbines. The components, relative advantages, limitations and design parameters of diffuser augmented horizontal axis tidal current turbines are presented in detail. CFD simulation of NACA 0016 airfoil is carried out to explore its potential for designing a diffuser. The core issues associated with diffuser augmented horizontal axis tidal current turbines are also discussed.

  7. Modular off-axis solar concentrator

    Energy Technology Data Exchange (ETDEWEB)

    Plesniak, Adam P; Hall, John C

    2015-01-27

    A solar concentrator including a housing defining a vertical axis and including a receiving wall connected to a reflecting wall to define an internal volume and an opening into the internal volume, wherein the reflecting wall defines at least one primary optical element, and wherein at least a portion of the reflecting wall includes a layer of reflective material, the housing further including a cover connected to the receiving wall and the reflecting wall to seal the opening, and at least one receiver mounted on the receiving wall such that a vertical axis of the receiver is disposed at a non-zero angle relative to the vertical axis of the housing, the receiver including at least one photovoltaic cell.

  8. Oxytocin and hypothalamo-pituitary- adrenal axis

    Directory of Open Access Journals (Sweden)

    Berrak Ç. Yeğen

    2010-05-01

    Full Text Available BSTRACT: Upon exposure to different types of stressors, neuroendocrine and behavioral responses that include the activation of the hypothalamus-pituitary-adrenal (HPA axis are given to allow the individuals to cope with stress conditions. It was proven that oxytocin, anonapeptide released from the posterior pituitary, has behavioral and stress-attenuating effects by dampening HPA activity. On the other hand, the neuropeptide was also shown to exert anti-inflammatory effects through the modulation of immune and inflammatory processes in several experimental models of tissue injury. The findings of recent studies suggest that the anti-inflammatory effect of oxytocin depends on its role on HPA axis activity and subsequent release of cortisol. Thus, oxytocin seems to restrain the activity within the HPA-axis, which becomes overactive during many inflammatory processes

  9. ELONGATED ODONTOID PROCESS OF AXIS VERTEBRA

    Directory of Open Access Journals (Sweden)

    Prathap Kumar J,

    2014-09-01

    Full Text Available Introduction: Odontoid process is a bony projection of axis around which the atlas rotates. It measures 1 to 1.25 cms in length and projects upwards from the body of Axis. An elongated odontoid process may narrow the foramen magnum causing compressive neurological symptoms. It can cause cervical stiffness, serious restrictions of neck movement, and even a bone-derived torticollis. Observation: During routine osteology classes, we encountered an Axis vertebra with an elongated odontoid process. The measurements of the elongated odontoid process were taken using digital Vernier slide calipers. Conclusion: Elongated odontoid process can be mistaken for fracture of dens in radiological images; hence the knowledge of elongated odontoid process is useful for the radiologists, neurosurgeons and orthopaedicians for accurate diagnosis and treatment involving cranio-vertebral junctions.

  10. New Urban Vertical Axis Wind Turbine Design

    Directory of Open Access Journals (Sweden)

    Alexandru-Mihai CISMILIANU

    2015-12-01

    Full Text Available This paper develops a different approach for enhancing the performance of Vertical Axis Wind Turbines for the use in the urban or rural environment and remote isolated residential areas. Recently the vertical axis wind turbines (VAWT have become more attractive due to the major advantages of this type of turbines in comparison to the horizontal axis wind turbines. We aim to enhance the overall performance of the VAWT by adding a second set of blades (3 x 2=6 blades following the rules of biplane airplanes. The model has been made to operate at a maximum power in the range of the TSR between 2 to 2.5. The performances of the VAWT were investigated numerically and experimentally and justify the new proposed design.

  11. A users guide to HPA axis research.

    Science.gov (United States)

    Spencer, Robert L; Deak, Terrence

    2016-11-18

    Glucocorticoid hormones (cortisol and corticosterone - CORT) are the effector hormones of the hypothalamic-pituitary-adrenal (HPA) axis neuroendocrine system. CORT is a systemic intercellular signal whose level predictably varies with time of day and dynamically increases with environmental and psychological stressors. This hormonal signal is utilized by virtually every cell and physiological system of the body to optimize performance according to circadian, environmental and physiological demands. Disturbances in normal HPA axis activity profiles are associated with a wide variety of physiological and mental health disorders. Despite numerous studies to date that have identified molecular, cellular and systems-level glucocorticoid actions, new glucocorticoid actions and clinical status associations continue to be revealed at a brisk pace in the scientific literature. However, the breadth of investigators working in this area poses distinct challenges in ensuring common practices across investigators, and a full appreciation for the complexity of a system that is often reduced to a single dependent measure. This Users Guide is intended to provide a fundamental overview of conceptual, technical and practical knowledge that will assist individuals who engage in and evaluate HPA axis research. We begin with examination of the anatomical and hormonal components of the HPA axis and their physiological range of operation. We then examine strategies and best practices for systematic manipulation and accurate measurement of HPA axis activity. We feature use of experimental methods that will assist with better understanding of CORT's physiological actions, especially as those actions impact subsequent brain function. This research approach is instrumental for determining the mechanisms by which alterations of HPA axis function may contribute to pathophysiology.

  12. Physics design of the DARHT 2nd axis accelerator cell

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Y J; Houck, T L; Reginato, L J; Shang, C C; Yu, S S

    1999-08-19

    The next generation of radiographic machines based on induction accelerators require very high brightness electron beams to realize the desired x-ray spot size and intensity. This high brightness must be maintained throughout the beam transport, from source to x-ray converter target. The accelerator for the second-axis of the Dual Axis Radiographic Hydrodynamic Test (DARHT) facility is being designed to accelerate a 4-kA, 2-{micro}s pulse of electrons to 20 MeV. After acceleration, the 2-{micro}s pulse will be chopped into a train of four 50-ns pulses with variable temporal spacing by rapidly deflecting the beam between a beam stop and the final transport section. The short beam pulses will be focused onto an x-ray converter target generating four radiographic pulses within the 2-{micro}s window. Beam instability due to interaction with the accelerator cells can very adversely effect the beam brightness and radiographic pulse quality. This paper describes the various issues considered in the design of the accelerator cell with emphasis on transverse impedance and minimizing beam instabilities.

  13. Off-Axis Undulator Radiation for CLIC Drive Beam Diagnostics

    CERN Document Server

    Jeff, A; Welsch, CP

    2013-01-01

    The Compact LInear Collider (CLIC) will use a novel acceleration scheme in which energy extracted from a very intense beam of relatively low-energy electrons (the Drive Beam) is used to accelerate a lower intensity Main Beam to very high energy. The high intensity of the Drive Beam, with pulses of more than 1015 electrons, poses a challenge for conventional profile measurements such as wire scanners. Thus, new non-invasive profile measurements are being investigated. In this paper we propose the use of relatively inexpensive permanent-magnet undulators to generate off-axis visible Synchrotron Radiation from the CLIC Drive Beam. The field strength and period length of the undulator should be designed such that the on-axis undulator wavelength is in the ultra-violet. A smaller but still useable amount of visible light is then generated in a hollow cone. This light can be reflected out of the beam pipe by a ring-shaped mirror placed downstream and imaged on a camera. In this contribution, results of SRW and ZEMA...

  14. DRIVE AND CONTROL OF VIRTUAL-AXIS NC MACHINE TOOLS

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    The structure features and driving modes of virtual-axis NC machine tools are studied.Accor- ding to different application requirements,the three-axis control method,the five-axis control method and the six-freedom control method are put forward.These results lay a foundation for the product development of the virtual-axis NC machine tools.

  15. Development and demonstration of a vertical axis wind turbine POWERHOUSE

    Science.gov (United States)

    Vosburgh, P. N.

    1984-06-01

    A performance of reliable lower cost base assembly and controls was designed for the electricity generating wind energy conversion system of the VAWTPOWER 185 wind turbine. The base assembly includes low speed shaft and couplings, disc or drum brake, hydraulic or pneumatic brake control systems, speed increasing gear box, high speed shaft and couplings, induction motor/generator, bottom rotor bearings, lightning and ground fault protection, support structure, and environmental protection. VAWTPOWER 185 is a 200 kW capacity Vertical Axis Wind Turbine rated 185 kW at 37 mph. After system analysis, subsystem definition, detailed design and engineering, and development of a test plan, two versions of the powerhouse were fabricated and tested. Both appear ready for commercial production.

  16. Triple-axis spectrometer DruechaL

    Energy Technology Data Exchange (ETDEWEB)

    Buehrer, W.; Keller, P. [Lab. for Neutron Scattering ETH Zurich, Zurich (Switzerland) and Paul Scherrer Institute, Villigen (Switzerland)

    1996-11-01

    DruechaL is a triple-axis spectrometer located at a cold guide. The characteristics of guide and instrument allow the use of a broad spectral range of neutrons. The resolution in momentum and energy transfer can be tuned to match the experimental requirements by using either collimators or focusing systems (monochromator, antitrumpet, analyser). (author) figs., tabs., refs.

  17. Resolution of a triple axis spectrometer

    DEFF Research Database (Denmark)

    Nielsen, Mourits; Bjerrum Møller, Hans

    1969-01-01

    A new method for obtaining the resolution function for a triple-axis neutron spectrometer is described, involving a combination of direct measurement and analytical calculation. All factors which contribute to the finite resolution of the instrument may be taken into account, and Gaussian...

  18. A Portable Single Axis Magnetic Gradiometer

    DEFF Research Database (Denmark)

    Merayo, José M.G.; Petersen, Jan Raagaard; Nielsen, Otto V

    2001-01-01

    The single axis magnetic gradiometer based on two compact detector compensation (CDC) fluxgate ringcore sensors separated 20 cm is described. Despite its high stability and precision better than 1 nT, the calibration procedures are not straightforward. Firstly, the mono-axial measurement does not...

  19. Tennis Rackets and the Parallel Axis Theorem

    Science.gov (United States)

    Christie, Derek

    2014-01-01

    This simple experiment uses an unusual graph straightening exercise to confirm the parallel axis theorem for an irregular object. Along the way, it estimates experimental values for g and the moment of inertia of a tennis racket. We use Excel to find a 95% confidence interval for the true values.

  20. The Trading Axis in Irkutsk Downtown

    Directory of Open Access Journals (Sweden)

    Elena Grigoryeva

    2016-10-01

    Full Text Available The article reveals a linear concentration of the trading function in the historical center of Irkutsk. It features historical prerequisites and continuation of the tradition in the post-Soviet period, given the conversion of plants and factories. The article analyses the current state and prospects of modernization of the trading axis with its transformation into a modern public space.

  1. ICl-mediated intramolecular twofold iodoarylation of diynes and diynyl diethers and amines: synthesis of bis(2H-hydronaphthalene and chromene) and 2H-quinoline bearing an alkenyl iodide moiety.

    Science.gov (United States)

    Mo, Juntae; Choi, Wonseok; Min, Jiae; Kim, Cheol-Eui; Eom, Dahan; Kim, Sung Hong; Lee, Phil Ho

    2013-11-15

    Electrophilic intramolecular twofold iodoarylation was developed from the reaction of diynes and diynyl diethers and amines with iodine monochloride under mild conditions, which produced bis(2H-hydronaphthalene and chromene) and 2H-quinoline bearing an alkenyl iodide moiety in good to excellent yields. These compounds underwent Pd-catalyzed cross-coupling reactions with arylboronic acid and indium tris(arylthiolate) to produce the functionalized styrene derivatives.

  2. Solar thermoelectric generator

    Science.gov (United States)

    Toberer, Eric S.; Baranowski, Lauryn L.; Warren, Emily L.

    2016-05-03

    Solar thermoelectric generators (STEGs) are solid state heat engines that generate electricity from concentrated sunlight. A novel detailed balance model for STEGs is provided and applied to both state-of-the-art and idealized materials. STEGs can produce electricity by using sunlight to heat one side of a thermoelectric generator. While concentrated sunlight can be used to achieve extremely high temperatures (and thus improved generator efficiency), the solar absorber also emits a significant amount of black body radiation. This emitted light is the dominant loss mechanism in these generators. In this invention, we propose a solution to this problem that eliminates virtually all of the emitted black body radiation. This enables solar thermoelectric generators to operate at higher efficiency and achieve said efficient with lower levels of optical concentration. The solution is suitable for both single and dual axis solar thermoelectric generators.

  3. Nanoscratch Characterization of GaN Epilayers on c- and a-Axis Sapphire Substrates

    Directory of Open Access Journals (Sweden)

    Wen Hua-Chiang

    2010-01-01

    Full Text Available Abstract In this study, we used metal organic chemical vapor deposition to form gallium nitride (GaN epilayers on c- and a-axis sapphire substrates and then used the nanoscratch technique and atomic force microscopy (AFM to determine the nanotribological behavior and deformation characteristics of the GaN epilayers, respectively. The AFM morphological studies revealed that pile-up phenomena occurred on both sides of the scratches formed on the GaN epilayers. It is suggested that cracking dominates in the case of GaN epilayers while ploughing during the process of scratching; the appearances of the scratched surfaces were significantly different for the GaN epilayers on the c- and a-axis sapphire substrates. In addition, compared to the c-axis substrate, we obtained higher values of the coefficient of friction (μ and deeper penetration of the scratches on the GaN a-axis sapphire sample when we set the ramped force at 4,000 μN. This discrepancy suggests that GaN epilayers grown on c-axis sapphire have higher shear resistances than those formed on a-axis sapphire. The occurrence of pile-up events indicates that the generation and motion of individual dislocation, which we measured under the sites of critical brittle transitions of the scratch track, resulted in ductile and/or brittle properties as a result of the deformed and strain-hardened lattice structure.

  4. Local auxin sources orient the apical-basal axis in Arabidopsis embryos.

    Science.gov (United States)

    Robert, Hélène S; Grones, Peter; Stepanova, Anna N; Robles, Linda M; Lokerse, Annemarie S; Alonso, Jose M; Weijers, Dolf; Friml, Jiří

    2013-12-16

    Establishment of the embryonic axis foreshadows the main body axis of adults both in plants and in animals, but underlying mechanisms are considered distinct. Plants utilize directional, cell-to-cell transport of the growth hormone auxin to generate an asymmetric auxin response that specifies the embryonic apical-basal axis. The auxin flow directionality depends on the polarized subcellular localization of PIN-FORMED (PIN) auxin transporters. It remains unknown which mechanisms and spatial cues guide cell polarization and axis orientation in early embryos. Herein, we provide conceptually novel insights into the formation of embryonic axis in Arabidopsis by identifying a crucial role of localized tryptophan-dependent auxin biosynthesis. Local auxin production at the base of young embryos and the accompanying PIN7-mediated auxin flow toward the proembryo are required for the apical auxin response maximum and the specification of apical embryonic structures. Later in embryogenesis, the precisely timed onset of localized apical auxin biosynthesis mediates PIN1 polarization, basal auxin response maximum, and specification of the root pole. Thus, the tight spatiotemporal control of distinct local auxin sources provides a necessary, non-cell-autonomous trigger for the coordinated cell polarization and subsequent apical-basal axis orientation during embryogenesis and, presumably, also for other polarization events during postembryonic plant life.

  5. Mortality of a captive axis deer (Axis axis) and a llama (Lama glama) due to ingestion of Wedelia glauca.

    Science.gov (United States)

    Giannitti, Federico; Margineda, Carlos A; Cid, María S; Diab, Santiago S; Weber, Natalia; Rodríguez, Alejandro; Campero, Carlos M; Odriozola, Ernesto R

    2012-11-01

    The current study describes a naturally occurring cluster of cases of Wedelia glauca intoxication. Seven of 14 axis deer (Axis axis) and 1 of 8 llamas (Lama glama) in a zoo of Buenos Aires province, Argentina, died suddenly after ingestion of a new batch of alfalfa (Medicago sativa) hay bales contaminated with the hepatotoxic plant W. glauca. Necropsies of 1 deer and 1 llama were performed. Pathological findings in both animals included severe diffuse acute centrilobular hepatocellular necrosis and hemorrhage, and clear yellowish translucent gelatinous edema on the wall of the gall bladder and the serosa of the choledochoduodenal junction. Fragments of W. glauca plants were identified in the hay based on the botanical characteristics of the leaves. Samples of gastric contents were examined by microhistological analysis, which identified epidermal fragments of W. glauca based on the presence of characteristic uniseriate glandular hairs (trichomes), confirming recent ingestion of W. glauca in both cases. The fragments were quantified and represented 5% of all examined vegetal fragments in the deer and 10% in the llama.

  6. Mechanical Coupling between Endoderm Invagination and Axis Extension in Drosophila.

    Directory of Open Access Journals (Sweden)

    Claire M Lye

    Full Text Available How genetic programs generate cell-intrinsic forces to shape embryos is actively studied, but less so how tissue-scale physical forces impact morphogenesis. Here we address the role of the latter during axis extension, using Drosophila germband extension (GBE as a model. We found previously that cells elongate in the anteroposterior (AP axis in the extending germband, suggesting that an extrinsic tensile force contributed to body axis extension. Here we further characterized the AP cell elongation patterns during GBE, by tracking cells and quantifying their apical cell deformation over time. AP cell elongation forms a gradient culminating at the posterior of the embryo, consistent with an AP-oriented tensile force propagating from there. To identify the morphogenetic movements that could be the source of this extrinsic force, we mapped gastrulation movements temporally using light sheet microscopy to image whole Drosophila embryos. We found that both mesoderm and endoderm invaginations are synchronous with the onset of GBE. The AP cell elongation gradient remains when mesoderm invagination is blocked but is abolished in the absence of endoderm invagination. This suggested that endoderm invagination is the source of the tensile force. We next looked for evidence of this force in a simplified system without polarized cell intercalation, in acellular embryos. Using Particle Image Velocimetry, we identify posteriorwards Myosin II flows towards the presumptive posterior endoderm, which still undergoes apical constriction in acellular embryos as in wildtype. We probed this posterior region using laser ablation and showed that tension is increased in the AP orientation, compared to dorsoventral orientation or to either orientations more anteriorly in the embryo. We propose that apical constriction leading to endoderm invagination is the source of the extrinsic force contributing to germband extension. This highlights the importance of physical

  7. Interaction of PGHS-2 and glutamatergic mechanisms controlling the ovine fetal hypothalamus-pituitary-adrenal axis.

    Science.gov (United States)

    Knutson, Nathan; Wood, Charles E

    2010-07-01

    Prostaglandins, generated within the fetal brain, are integral components of the mechanism controlling the fetal hypothalamus-pituitary-adrenal (HPA) axis. Previous studies in this laboratory demonstrated that prostaglandin G/H synthase isozyme 2 (PGHS-2) inhibition reduces the fetal HPA axis response to cerebral hypoperfusion, blocks the preparturient rise in fetal plasma ACTH concentration, and delays parturition. We also discovered that blockade of N-methyl-d-aspartate (NMDA) receptors reduces the fetal ACTH response to cerebral hypoperfusion. The present study was designed to test the hypothesis that PGHS-2 action and the downstream effect of HPA axis stimulation are stimulated by NMDA-mediated glutamatergic neurotransmission. Chronically catheterized late-gestation fetal sheep (n = 8) were injected with NMDA (1 mg iv). All responded with increases in fetal plasma ACTH and cortisol concentrations. Pretreatment with resveratrol (100 mg iv, n = 5), a specific inhibitor of PGHS-1, did not alter the magnitude of the HPA axis response to NMDA. Pretreatment with nimesulide (10 mg iv, n = 6), a specific inhibitor of PGHS-2, significantly reduced the HPA axis response to NMDA. To further explore this interaction, we injected NMDA in six chronically catheterized fetal sheep that were chronically infused with nimesulide (n = 6) at a rate of 1 mg/day into the lateral cerebral ventricle for 5-7 days. In this group, there was no significant ACTH response to NMDA. Finally, we tested whether the HPA axis response to prostaglandin E(2) (PGE(2)) is mediated by NMDA receptors. Seven chronically catheterized late-gestation fetal sheep were injected with 100 ng of PGE(2), which significantly increased fetal plasma ACTH and cortisol concentrations. Pretreatment with ketamine (10 mg iv), an NMDA antagonist, did not alter the ACTH or cortisol response to PGE(2). We conclude that generation of prostanoids via the action of PGHS-2 in the fetal brain augments the fetal HPA axis response

  8. Two-axis joint assembly and method

    Science.gov (United States)

    Le, Thang D. (Inventor); Lewis, James L. (Inventor); Carroll, Monty B. (Inventor)

    2010-01-01

    In an embodiment, a two-axis joint that utilizes planar reactions to handle moments applied to the side of the joint thereby allowing the device to remain low profile and compact with minimal intrusion to the mounting surface of the two-axis joint. To handle larger moments, the diameter of the planar member can be increased without increasing the overall height of the joint assembly thereby retaining the low profile thereof. Upper and lower antifriction bearings may be positioned within a housing engage the planar member to reduce rotational friction. The upper and lower bearings and a hub which supports the planar member transfer forces produced by moments applied to the side of the joint so as to spread the forces over the area of the housing.

  9. Determining the Stellar Spin Axis Orientation

    Science.gov (United States)

    Lesage, Anna-Lea; Wiedemann, Gunter

    2015-01-01

    We present an observing method that permits the determination of the absolute stellar spin axis position angle based on spectro-astrometric observations for slowly-rotating late-type stars. This method is complementary to current interferometric observations that determine the orientation of stellar spin axis for early-type fast-rotating stars. Spectro-astrometry enables us to study phenomena below the diffraction limit, at the milli-arcsecond scale. It relies on the wavelength dependent variations of the centroid position of a structured source in a long-slit spectrum. A rotating star has a slight tilt in its spectral lines, which induces a displacement of the photocentre's position. By monitoring the amplitude of the displacement for varying slit orientations, we can infer the absolute position angle of the stellar spin axis. Finally, we present first observational results on Aldebaran obtained with the Thüringer Landesternwarte high resolution spectrograph. We were able to retrieve Aldebaran's position angle with less than 10° errors.

  10. Modeling the brain-pituitary-gonad axis in salmon

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jonghan; Hayton, William L.; Schultz, Irv R.

    2006-08-24

    To better understand the complexity of the brain-pituitary-gonad axis (BPG) in fish, we developed a biologically based pharmacodynamic model capable of accurately predicting the normal functioning of the BPG axis in salmon. This first-generation model consisted of a set of 13 equations whose formulation was guided by published values for plasma concentrations of pituitary- (FSH, LH) and ovary- (estradiol, 17a,20b-dihydroxy-4-pregnene-3-one) derived hormones measured in Coho salmon over an annual spawning period. In addition, the model incorporated pertinent features of previously published mammalian models and indirect response pharmacodynamic models. Model-based equations include a description of gonadotropin releasing hormone (GnRH) synthesis and release from the hypothalamus, which is controlled by environmental variables such as photoperiod and water temperature. GnRH stimulated the biosynthesis of mRNA for FSH and LH, which were also influenced by estradiol concentration in plasma. The level of estradiol in the plasma was regulated by the oocytes, which moved along a maturation progression. Estradiol was synthesized at a basal rate and as oocytes matured, stimulation of its biosynthesis occurred. The BPG model can be integrated with toxico-genomic, -proteomic data, allowing linkage between molecular based biomarkers and reproduction in fish.

  11. Harnessing Tidal Energy Using Vertical Axis Tidal Turbine

    Directory of Open Access Journals (Sweden)

    Syed Shah Khalid

    2013-01-01

    Full Text Available An overview of the current design practices in the field of Renewable Energy (RE is presented; also paper delineates the background to the development of unique and novel techniques for power generation using the kinetic energy of tidal streams and other marine currents. Also this study focuses only on vertical axis tidal turbine. Tidal stream devices have been developed as an alternative method of extracting the energy from the tides. This form of tidal power technology poses less threat to the environment and does not face the same limiting factors associated with tidal barrage schemes, therefore making it a more feasible method of electricity production. Large companies are taking interest in this new source of power. There is a rush to research and work with this new energy source. Marine scientists are looking into how much these will affect the environment, while engineers are developing turbines that are harmless for the environment. In addition, the progression of technological advancements tracing several decades of R & D efforts on vertical axis turbines is highlighted.

  12. A low-noise, high-bandwidth magnetically-levitated momentum-wheel for 3-axis attitude control from a single wheel

    OpenAIRE

    Seddon, Jon; Pechev, Alexandre

    2009-01-01

    This paper proposes a new concept for attitude actuation for small satellites that uses active magnetic bearings to support and tilt a spinning rotor to provide 3-axis attitude control of the satellite using a single actuator. A controlled 3D motion in the spinning rotor provides a conventional torque output about the momentum axis and a gyroscopic torque output about any direction in the plane normal to the spinning axis. Therefore, a single tilting momentum-wheel can generate torque along t...

  13. Neuroanatomy and physiology of the avian hypothalamic/pituitary axis: clinical aspects.

    Science.gov (United States)

    Ritchie, Midge

    2014-01-01

    This article describes the anatomy of the avian hypothalamic/pituitary axis, the hypothalamic-pituitary-thyroid axis, the hypothalamic-pituitary-adrenal axis, the hypothalamic-pituitary-gonadal axis, the somatotrophic axis, and neurohypophysis.

  14. An integrated MEMS piezoresistive tri-axis accelerometer

    Science.gov (United States)

    Yongping, Zhang; Changde, He; Jiaqi, Yu; Chunhui, Du; Juanting, Zhang; Xiujian, Chou; Wendong, Zhang

    2013-10-01

    An integrated MEMS accelerometer has been designed and fabricated. The device, which is based on the piezoresistive effect, accomplishes the detection of three components of acceleration by using piezoresistors to compose three Wheatstone bridges that are sensitive to the only given orientation. The fabrication of the accelerometer is described, and the theory behind its operation developed. Experimental results on sensitivity, cross-axis-coupling degree, and linearity are presented. The sensitivity of X, Y and Z were 5.49 mV/g, 5.12 mV/g and 4.82 mV/g, respectively; the nonlinearity of X, Y and Z were 0.01%, 0.04% and 0.01%, respectively; the cross-axis-coupling factor of X axis to Y axis and Z axis are 0.119% and 2.26% the cross-axis-coupling factor of Y axis to X axis and Z axis are 0.157% and 4.12% the cross-axis-coupling factor of Z axis to X axis and Y axis are 0.511% and 0.938%. The measured performance indexes attain accurate vector-detection in practical applications, and even at a navigation level. In conclusion, the accelerometer is a highly integrated sensor.

  15. Increasing Plant Availability by Mechanical Checking of the Cement Rotary Kiln Axis

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    A periodic check of the cement rotary kiln axis is needed within the framework of preventive maintenance for maintaining high plant availability. The fourth generation “KAS-4” measuring system was developed by Wuhan University of Technology in 1999. The system can be carried out with rotating or stationary kiln plant. The same is true of the measurement of tire and supporting roller diameters, the clearance of tires, the position of rollers, the machining of tires and rollers, the slopes of roller surfaces, the deflection of gear, the axis of kiln. The system has been applied to the measurement for 10 sets of cement rotary kiln in China.

  16. Nonlinear characterization of a single-axis acoustic levitator

    Energy Technology Data Exchange (ETDEWEB)

    Andrade, Marco A. B. [Institute of Physics, University of São Paulo, São Paulo (Brazil); Ramos, Tiago S.; Okina, Fábio T. A.; Adamowski, Julio C. [Department of Mechatronics and Mechanical Systems Engineering, Escola Politécnica, University of São Paulo, São Paulo (Brazil)

    2014-04-15

    The nonlinear behavior of a 20.3 kHz single-axis acoustic levitator formed by a Langevin transducer with a concave radiating surface and a concave reflector is experimentally investigated. In this study, a laser Doppler vibrometer is applied to measure the nonlinear sound field in the air gap between the transducer and the reflector. Additionally, an electronic balance is used in the measurement of the acoustic radiation force on the reflector as a function of the distance between the transducer and the reflector. The experimental results show some effects that cannot be described by the linear acoustic theory, such as the jump phenomenon, harmonic generation, and the hysteresis effect. The influence of these nonlinear effects on the acoustic levitation of small particles is discussed.

  17. Software tool for horizontal-axis wind turbine simulation

    Energy Technology Data Exchange (ETDEWEB)

    Vitale, A.J. [Instituto Argentino de Oceanografia, Camino La Carrindanga Km. 7, 5 CC 804, B8000FWB Bahia Blanca (Argentina); Universidad Tecnologica Nacional Facultad Regional Bahia Blanca, GESE, 11 de Abril 461, B8000LMI Bahia Blanca (Argentina); Dpto. de Ing. Electrica y de Computadoras, Universidad Nacional del Sur, Av. Alem 1253, 8000 Bahia Blanca (Argentina); Rossi, A.P. [Universidad Tecnologica Nacional Facultad Regional Bahia Blanca, GESE, 11 de Abril 461, B8000LMI Bahia Blanca (Argentina); Dpto. de Ing. Electrica y de Computadoras, Universidad Nacional del Sur, Av. Alem 1253, 8000 Bahia Blanca (Argentina)

    2008-07-15

    The main problem of a wind turbine generator design project is the design of the right blades capable of satisfying the specific energy requirement of an electric system with optimum performance. Once the blade has been designed for optimum operation at a particular rotor angular speed, it is necessary to determine the overall performance of the rotor under the range of wind speed that it will encounter. A software tool that simulates low-power, horizontal-axis wind turbines was developed for this purpose. With this program, the user can calculate the rotor power output for any combination of wind and rotor speeds, with definite blade shape and airfoil characteristics. The software also provides information about distribution of forces along the blade span, for different operational conditions. (author)

  18. Dynamic behavior analysis for a six axis industrial machining robot

    CERN Document Server

    Bisu, Claudiu-Florinel; Gérard, Alain; K'Nevez, Jean-Yves

    2012-01-01

    The six axis robots are widely used in automotive industry for their good repeatability (as defined in the ISO92983) (painting, welding, mastic deposition, handling etc.). In the aerospace industry, robot starts to be used for complex applications such as drilling, riveting, fiber placement, NDT, etc. Given the positioning performance of serial robots, precision applications require usually external measurement device with complexes calibration procedure in order to reach the precision needed. New applications in the machining field of composite material (aerospace, naval, or wind turbine for example) intend to use off line programming of serial robot without the use of calibration or external measurement device. For those applications, the position, orientation and path trajectory precision of the tool center point of the robot are needed to generate the machining operation. This article presents the different conditions that currently limit the development of robots in robotic machining applications. We ana...

  19. Low-power broadband homonuclear dipolar recoupling in MAS NMR by two-fold symmetry pulse schemes for magnetization transfers and double-quantum excitation

    Science.gov (United States)

    Teymoori, Gholamhasan; Pahari, Bholanath; Edén, Mattias

    2015-12-01

    We provide an experimental, numerical, and high-order average Hamiltonian evaluation of an open-ended series of homonuclear dipolar recoupling sequences, SR2 2p 1 with p = 1, 2, 3, … . While operating at a very low radio-frequency (rf) power, corresponding to a nutation frequency of 1/2 of the magic-angle spinning (MAS) rate (ωnut =ωr / 2), these recursively generated double-quantum (2Q) dipolar recoupling schemes offer a progressively improved compensation to resonance offsets and rf inhomogeneity for increasing pulse-sequence order p. The excellent recoupling robustness to these experimental obstacles, as well as to CSA, is demonstrated for 2Q filtering (2QF) experiments and for driving magnetization transfers in 2D NMR correlation spectroscopy, where the sequences may provide either double or zero quantum dipolar Hamiltonians during mixing. Experimental and numerical demonstrations, which mostly target conditions of "ultra-fast" MAS (≳50 kHz) and high magnetic fields, are provided for recoupling of 13C across a wide range of isotropic and anisotropic chemical shifts, as well as dipolar coupling constants, encompassing [2,3-13C2 ]alanine, [1,3-13C2 ]alanine, diammonium [1,4-13C2 ]fumarate, and [U-13 C]tyrosine. When compared at equal power levels, a superior performance is observed for the SR2p 1 sequences with p ⩾ 3 relative to existing and well-established 2Q recoupling techniques. At ultra-fast MAS, proton decoupling is redundant during the homonuclear dipolar recoupling of dilute spins in organic solids, which renders the family of SR2p 1 schemes the first efficient 2Q recoupling option for general applications, such as 2Q-1Q correlation NMR and high-order multiple-quantum excitation, under truly low-power rf conditions.

  20. The optical axis optimization in measurement of decentration of lens

    Science.gov (United States)

    Wang, Yajing; Yang, Lin; Wang, Chunyu

    2013-09-01

    Measure of optical decentration plays an important role in inspection, installation and adjustment of optical system. This article describes optical measurement principle of decentration, analyzes the reason of the decentration measurement accuracy, and indicates the necessity of optimizing the optical axis. Finally, because of the error of the decentration optical axis fitting. A new method of optical axis optimization is put forward here. A mathematical model to find the best optical axis is established, which improved the optical performance of the system.

  1. Micromachined dual input axis rate gyroscope

    Science.gov (United States)

    Juneau, Thor Nelson

    The need for inexpensive yet reliable angular rate sensors in fields ranging from automotive to consumer electronics has motivated prolific micromachined rate gyroscope research. The vast majority of research has focused on single input axis rate gyroscopes based upon either translational resonance, such as tuning forks, or structural mode resonance, such as vibrating rings. However, this work presents a novel, contrasting approach based on angular resonance of a rotating rigid rotor suspended by torsional springs. The inherent symmetry of the circular design allows angular rate measurement about two axes simultaneously, hence the name micromachined dual-axis rate gyroscope. The underlying theory of operation, mechanical structure design optimization, electrical interface circuitry, and signal processing are described in detail. Several operational versions were fabricated using two different fully integrated surface micromachining processes as proof of concept. The heart of the dual-axis rate gyroscope is a ˜2 mum thick polysilicon disk or rotor suspended above the substrate by a four beam suspension. When this rotor in driven into angular oscillation about the axis perpendicular to the substrate, a rotation rate about the two axes parallel to the substrate invokes an out of plane rotor tilting motion due to Coriolis acceleration. This tilting motion is capacitively measured and on board integrated signal processing provides two output voltages proportional to angular rate input about the two axes parallel to the substrate. The design process begins with the derivation of gyroscopic dynamics. The equations suggest that tuning sense mode frequencies to the drive oscillation frequency can vastly increase mechanical sensitivity. Hence the supporting four beam suspension is designed such that electrostatic tuning can match modes despite process variations. The electrostatic tuning range is limited only by rotor collapse to the substrate when tuning-voltage induced

  2. Servo-controlling structure of five-axis CNC system for real-time NURBS interpolating

    Science.gov (United States)

    Chen, Liangji; Guo, Guangsong; Li, Huiying

    2017-07-01

    NURBS (Non-Uniform Rational B-Spline) is widely used in CAD/CAM (Computer-Aided Design / Computer-Aided Manufacturing) to represent sculptured curves or surfaces. In this paper, we develop a 5-axis NURBS real-time interpolator and realize it in our developing CNC(Computer Numerical Control) system. At first, we use two NURBS curves to represent tool-tip and tool-axis path respectively. According to feedrate and Taylor series extension, servo-controlling signals of 5 axes are obtained for each interpolating cycle. Then, generation procedure of NC(Numerical Control) code with the presented method is introduced and the method how to integrate the interpolator into our developing CNC system is given. And also, the servo-controlling structure of the CNC system is introduced. Through the illustration, it has been indicated that the proposed method can enhance the machining accuracy and the spline interpolator is feasible for 5-axis CNC system.

  3. Realization Methodology of a 5-axis Spline Interpolator in an Open CNC System

    Institute of Scientific and Technical Information of China (English)

    Wang Yongzhang; Ma Xiongbo; Chen Liangji; Han Zhenyu

    2007-01-01

    By making use of the advantages of non-uniform rational B-spline (NURBS) curves to represent spatial curves, an instruction format with double NURBS curves suitable for 5-axis coordinated real-time interpolation is presented to replace the current 5-axis coordinated linear interpolation method defective in low-speed, low-accuracy and enormous numerical control (NC) files in sculptured surface machining. A generation procedure of the NC files with the presented format is introduced and the method to realize the interpolation in an open computer numerical control (CNC) system is developed by ourselves. These illustrated the feasibility of the proposed method and its capability of avoiding all the shortages of 5-axis linear interpolation method.

  4. The energy-redox axis in aging and age-related neurodegeneration.

    Science.gov (United States)

    Yap, Li-Peng; Garcia, Jerome V; Han, Derick; Cadenas, Enrique

    2009-11-30

    Decrease in mitochondrial energy-transducing capacity is a feature of the aging process that accompanies redox alterations, such as increased generation of mitochondrial oxidants, altered GSH status, and increased protein oxidation. The decrease in mitochondrial energy-transducing capacity and altered redox status should be viewed as a concerted process that embodies the mitochondrial energy-redox axis and is linked through various mechanisms including: (a) an inter-convertible reducing equivalents pool (i.e., NAD(P)(+)/NAD(P)H) and (b) redox-mediated protein post-translational modifications involved in energy metabolism. The energy-redox axis provides the rationale for therapeutic approaches targeted to each or both component(s) of the axis that effectively preserves or improve mitochondrial function and that have implications for aging and age-related neurodegenerative disorders.

  5. Segmental patterning of the vertebrate embryonic axis.

    Science.gov (United States)

    Dequéant, Mary-Lee; Pourquié, Olivier

    2008-05-01

    The body axis of vertebrates is composed of a serial repetition of similar anatomical modules that are called segments or metameres. This particular mode of organization is especially conspicuous at the level of the periodic arrangement of vertebrae in the spine. The segmental pattern is established during embryogenesis when the somites--the embryonic segments of vertebrates--are rhythmically produced from the paraxial mesoderm. This process involves the segmentation clock, which is a travelling oscillator that interacts with a maturation wave called the wavefront to produce the periodic series of somites. Here, we review our current understanding of the segmentation process in vertebrates.

  6. 整体叶轮五轴数控插铣加工刀位轨迹生成算法研究%Research on generation algorithm of five-axis NC plunge milling tool-path for an integral impeller

    Institute of Scientific and Technical Information of China (English)

    戚家亮; 安鲁陵; 修春松

    2011-01-01

    In order to improve the efficiency and quality of integral impeller rough machining,a tool-path planning method of five-axis plunge milling for integral impeller is proposedAccording to the geometric feature of the integral impeller and plunge milling characters,cross-section plane family perpendicular to the impeller axis is defined,then the unilateral enveloping beeline family of the section line of the cross-section plane and the blade surface is constructed as the boundary surface cutter location,and the tool-path of the impeller is calculated by interpolating the boundary cutter location.Afterwards a plunge milling software module is developed using UG/Open API.It is verified by actual example that the method of tool-path planning is effective.%为了提高整体叶轮粗加工效率和质量,提出了一种整体叶轮五轴插铣加工刀位轨迹的计算方法.根据整体叶轮的几何特征和插铣特点,定义与叶轮轴线垂直的截平面族,构造截平面与叶片型面交线的单侧包络直线族,作为边界面加工刀位,在边界面刀位之间插值,得到整个流道的插铣加工刀位轨迹.运用UG/Open API开发了整体叶轮插铣加工软件模块,最后通过实例验证了所提出的方法是有效的.

  7. Rapid 2-axis scanning lidar prototype

    Science.gov (United States)

    Hartsell, Daryl; LaRocque, Paul E.; Tripp, Jeffrey

    2016-10-01

    The rapid 2-axis scanning lidar prototype was developed to demonstrate high-precision single-pixel linear-mode lidar performance. The lidar system is a combined integration of components from various commercial products allowing for future customization and performance enhancements. The intent of the prototype scanner is to demonstrate current stateof- the-art high-speed linear scanning technologies. The system consists of two pieces: the sensor head and control unit. The senor head can be installed up to 4 m from the control box and houses the lidar scanning components and a small RGB camera. The control unit houses the power supplies and ranging electronics necessary for operating the electronics housed inside the sensor head. This paper will discuss the benefits of a 2-axis scanning linear-mode lidar system, such as range performance and a userselectable FOV. Other features include real-time processing of 3D image frames consisting of up to 200,000 points per frame.

  8. Model for performance prediction in multi-axis machining

    CERN Document Server

    Lavernhe, Sylvain; Lartigue, Claire; 10.1007/s00170-007-1001-4

    2009-01-01

    This paper deals with a predictive model of kinematical performance in 5-axis milling within the context of High Speed Machining. Indeed, 5-axis high speed milling makes it possible to improve quality and productivity thanks to the degrees of freedom brought by the tool axis orientation. The tool axis orientation can be set efficiently in terms of productivity by considering kinematical constraints resulting from the set machine-tool/NC unit. Capacities of each axis as well as some NC unit functions can be expressed as limiting constraints. The proposed model relies on each axis displacement in the joint space of the machine-tool and predicts the most limiting axis for each trajectory segment. Thus, the calculation of the tool feedrate can be performed highlighting zones for which the programmed feedrate is not reached. This constitutes an indicator for trajectory optimization. The efficiency of the model is illustrated through examples. Finally, the model could be used for optimizing process planning.

  9. Comparison of 4 cm Z-axis and 16 cm Z-axis multidetector CT perfusion

    Energy Technology Data Exchange (ETDEWEB)

    Page, Mark; Nandurkar, Dee; Crossett, Marcus Peter; Stuckey, Stephen L.; Lau, Kenneth P.; Kenning, Nicholas; Troupis, John M. [Monash Medical Centre, Department of Diagnostic Imaging, Southern Health Network, Clayton, Victoria (Australia)

    2010-06-15

    The aim of the study was to compare 4 cm with 16 cm Z-axis coverage in the assessment of brain CT perfusion (CTP) using. 320 slice multidetector CT A retrospective non-randomised review of CTP performed on MD320 CT between September 2008 and January 2009 was undertaken. Two experienced readers reviewed the studies along with the 4 cm and 16 cm Z-axis CTP image data set. The outcome parameters assessed were the extent of the original finding, any additional findings and a change of diagnosis. 14 out of 27 patients were found to have abnormal CTP (mean age 58.1 years, 9 male). The 16 cm Z-axis increased the accuracy of the infarct core in 78% and ischaemic penumbra quantification in 100% of the cases. It also diagnosed additional infarcts in the same vascular territory in 28% of cases and in a different vascular territory in 14%. The increased field of view with MD320 better defines the true extent of the infarct core and ischaemic penumbra. It also identified other areas of infarction that were not identified on the 4 cm Z-axis. (orig.)

  10. Polarized triple-axis spectrometer TASP

    Energy Technology Data Exchange (ETDEWEB)

    Boeni, P.; Keller, P. [Lab. for Neutron Scattering ETH Zurich, Zurich (Switzerland) and Paul Scherrer Institute, Villigen (Switzerland)

    1996-11-01

    The polarized triple-axis spectrometer TASP at SINQ has been optimized for measuring magnetic cross sections in condensed matter. The neutrons are polarized or analyzed either by means of benders or Heusler monochromators. The beam divergence, i.e. the intensity, and the spectral range of the neutrons is rather large because of the supermirror coatings of the feeding neutron guide. The intensity can be further increased at the sample position by means of a focussing monochromator and a focussing anti-trumpet. The end position of TASP allows the tailoring of the neutron beam already before the monochromator and to scatter neutrons over very wide ranges of angles. (author) 6 figs., 1 tab., 8 refs.

  11. Beyond Sovereignty: The Twofold Subversion of "Bildung"

    Science.gov (United States)

    Reichenbach, Roland

    2003-01-01

    Few concepts in the German tradition of human studies--the so-called "Geisteswissenschaften"--have had the capacity to birth such intense expectations and hopes as the concept of "Bildung". There is general agreement that the concept of "Bildung" includes both an objective and a subjective component. The first refers to "culture" in its broadest…

  12. Providing Virtual Execution Environments: A Twofold Illustration

    CERN Document Server

    Grehant, Xavier

    2008-01-01

    Platform virtualization helps solving major grid computing challenges: share resource with flexible, user-controlled and custom execution environments and in the meanwhile, isolate failures and malicious code. Grid resource management tools will evolve to embrace support for virtual resource. We present two open source projects that transparently supply virtual execution environments. Tycoon has been developed at HP Labs to optimise resource usage in creating an economy where users bid to access virtual machines and compete for CPU cycles. SmartDomains provides a peer-to-peer layer that automates virtual machines deployment using a description language and deployment engine from HP Labs. These projects demonstrate both client-server and peer-to-peer approaches to virtual resource management. The first case makes extensive use of virtual machines features for dynamic resource allocation. The second translates virtual machines capabilities into a sophisticated language where resource management components can b...

  13. Simulation of flow over double-element airfoil and wind tunnel test for use in vertical axis wind turbine

    DEFF Research Database (Denmark)

    Chougule, Prasad; Nielsen, Søren R.K.

    2014-01-01

    been made to utilize high lift technology for vertical axis wind turbines in order to improve power efficiency. High lift is obtained by double-element airfoil mainly used in aeroplane wing design. In this current work a low Reynolds number airfoil is selected to design a double-element airfoil blade......Nowadays, small vertical axis wind turbines are receiving more attention due to their suitability in micro-electricity generation. There are few vertical axis wind turbine designs with good power curve. However, the efficiency of power extraction has not been improved. Therefore, an attempt has...... for use in vertical axis wind turbine to improve the power efficiency. Double-element airfoil blade design consists of a main airfoil and a slat airfoil. Orientation of slat airfoil is a parameter of investigation in this paper and air flow simulation over double-element airfoil. With primary wind tunnel...

  14. Accurate Compensation of Attitude Angle Error in a Dual-Axis Rotation Inertial Navigation System

    Science.gov (United States)

    Jiang, Rui; Yang, Gongliu; Zou, Rui; Wang, Jing; Li, Jing

    2017-01-01

    In the dual-axis rotation inertial navigation system (INS), besides the gyro error, accelerometer error, rolling misalignment angle error, and the gimbal angle error, the shaft swing angle and the axis non-orthogonal angle also affect the attitude accuracy. Through the analysis of the structure, we can see that the shaft swing angle and axis non-orthogonal angle will produce coning errors which cause the fluctuation of the attitude. According to the analysis of the rotation vector, it can be seen that the coning error will generate additional drift velocity along the rotating shaft, which can reduce the navigation precision of the system. In this paper, based on the establishment of the modulation average frame, the vector projection is carried out, and then the attitude conversion matrix and the attitude error matrix mainly including the shaft swing angle and axis non-orthogonal are obtained. Because the attitude angles are given under the static condition, the shaft swing angle and the axis non-orthogonal angle are estimated by the static Kalman filter (KF). This kind of KF method has been widely recognized as the standard optimal estimation tool for estimating the parameters such as coning angles (α1 , α2), initial phase angles (ϕ1,ϕ2), and the non-perpendicular angle (η). In order to carry out the system level verification, a dual axis rotation INS is designed. Through simulation and experiments, the results show that the amplitudes of the attitude angles’ variation are reduced by about 20%–30% when the shaft rotates. The attitude error equation is reasonably simplified and the calibration method is accurate enough. The attitude accuracy is further improved. PMID:28304354

  15. A water-cooled x-ray monochromator for using off-axis undulator beam.

    Energy Technology Data Exchange (ETDEWEB)

    Khounsary, A.; Maser, J.

    2000-12-11

    Undulator beamlines at third-generation synchrotrons x-ray sources are designed to use the high-brilliance radiation that is contained in the central cone of the generated x-ray beams. The rest of the x-ray beam is often unused. Moreover, in some cases, such as in the zone-plate-based microfocusing beamlines, only a small part of the central radiation cone around the optical axis is used. In this paper, a side-station branch line at the Advanced Photon Source that takes advantage of some of the unused off-axis photons in a microfocusing x-ray beamline is described. Detailed information on the design and analysis of a high-heat-load water-cooled monochromator developed for this beamline is provided.

  16. Coherent off-axis undulator radiation from short electron bunches

    Directory of Open Access Journals (Sweden)

    C. P. Neuman

    2000-03-01

    Full Text Available The nature of off-axis undulator radiation is discussed. Of particular interest is coherent off-axis radiation, where the wavelengths of emission are longer than the electron bunch length. We show how this off-axis radiation may be used to measure relative electron bunch lengths. The theory is presented, and calculated spectra are presented in a number of cases of interest.

  17. HIF2α–arginase axis is essential for the development of pulmonary hypertension

    OpenAIRE

    Cowburn, Andrew S.; Crosby, Alexi; Macias, David; Branco, Cristina; Colaço, Renato D. D. R.; Southwood, Mark; Toshner, Mark; Crotty Alexander, Laura E.; Morrell, Nicholas W.; Chilvers, Edwin R.; Johnson, Randall S.

    2016-01-01

    The expression of hypoxia-inducible factor (HIF)-2α in pulmonary endothelium of mice influences pulmonary vascular resistance and development of hypoxic pulmonary hypertension (PH) via an arginase-1–dependent mechanism. The HIF-2α:arginase-1 axis influences the homeostatic regulation of nitric oxide synthesis in the lung. Impaired generation of this vasoactive agent contributes to the initial development and vascular remodeling process of PH.

  18. A comparison of on-axis and off-axis heliostat alignment strategies

    Energy Technology Data Exchange (ETDEWEB)

    Jones, S.A.

    1996-03-01

    Heliostat installation and alignment costs will be an important element in future solar power tower projects. The predicted annual performances of on- and-off axis strategies are compared for 95 m{sup 2} flat-glass heliostats and an external, molten-salt receiver. Actual approaches to heliostat alignment that have been used in the past are briefly discussed, and relative strengths and limitations are noted. The optimal approach can vary with the application.

  19. Growth Hormone-Insulin-Like Growth Factor Axis, Thyroid Axis, Prolactin, and Exercise.

    Science.gov (United States)

    Hackney, Anthony C; Davis, Hope C; Lane, Amy R

    2016-01-01

    This chapter addresses what is known about the endocrine system components growth hormone (GH)-insulin-like growth factor (IGF) axis, thyroid axis, and prolactin relative to exercise and exercise training. Each one of these hormone axes contributes to the maintenance of homeostasis in the body through impact on a multitude of physiological systems. The homeostatic disruption of exercise causes differing responses in each hormone axis. GH levels increase with sufficient stimulation, and IGFs are released in response to GH from the anterior pituitary providing multiple roles including anabolic properties. Changes in the thyroid hormones T3 and T4 vary greatly with exercise, from increases/decreases to no change in levels across different exercise types, intensities and durations. These ambiguous findings could be due to numerous confounding factors (e.g. nutrition status) within the research. Prolactin increases proportionally to the intensity of the exercise. The magnitude may be augmented with extended durations; conflicting findings have been reported with resistance training. While the responses to exercise vary, it appears there may be overall adaptive and regenerative impacts on the body into recovery by these hormones through immune and tissue inflammatory responses/mediations. Nonetheless, well-designed exercise research studies are still needed on each of these hormones, especially thyroid hormones and prolactin.

  20. Neuroactive steroids and stress axis regulation: Pregnancy and beyond.

    Science.gov (United States)

    Brunton, Paula J

    2016-06-01

    The hypothalamo-pituitary-adrenal (HPA) axis plays a critical role in regulating responses to stress and long term dysregulation of the HPA axis is associated with higher rates of mood disorders. There are circumstances where the HPA axis is more or less responsive to stress. For example, during late pregnancy ACTH and corticosterone responses to stress are markedly suppressed, whereas in offspring born to mothers that experienced repeated stress during pregnancy, the HPA axis is hyper-responsive to stress. Neuroactive steroids such as allopregnanolone, tetrahydrodeoxycorticosterone (THDOC) and androstanediol can modulate HPA axis activity and concentrations of some neuroactive steroids in the brain are altered during pregnancy and following stress. Thus, here altered neurosteroidogenesis is proposed as a mechanism that could underpin the dynamic changes in HPA axis regulation typically observed in late pregnant and in prenatally stressed individuals. In support of this hypothesis, evidence in rats demonstrates that elevated levels of allopregnanolone in pregnancy induce a central inhibitory opioid mechanism that serves to minimize stress-induced HPA axis activity. Conversely, in prenatally stressed rodents, where HPA axis stress responses are enhanced, evidence indicates the capacity of the brain for neurosteroidogenesis is reduced. Understanding the mechanisms involved in adaptations in HPA axis regulation may provide insights for manipulating stress sensitivity and for developing therapies for stress-related disorders in humans. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. The multi-axis vibration environment and man.

    Science.gov (United States)

    Lovesey, E J

    1970-12-01

    Many investigations into the effects of vibration on man have been performed since Mallock's first study of London Underground vibrations in 1902. The vibration research has tended to be confined to the vertical (heave) axis, yet recent experiments have indicated that low frequency vibration along the lateral (sway) axis has a greater adverse effect upon comfort and performance. Measurements of the vibration environments in current forms of transport including motor vehicles, hovercraft and aircraft etc have shown that appreciable quantities of vibration along all three axes exist. Further vibration research should consider the effects of multi-axis vibrations upon man rather than limit tests to single axis vibration.

  2. Rotation Axis Variation Due To Spin Orbit Resonance

    CERN Document Server

    Gallavotti, G

    1993-01-01

    Abstract: rotation axis variation due to spin orbit resonance: conference report; keywords: planetary precession, rigid body, chaos, KAM, Arnold diffusion, averaging, celestial mechanics, classical mechanics, large deviations

  3. Circadian genes, the stress axis, and alcoholism.

    Science.gov (United States)

    Sarkar, Dipak K

    2012-01-01

    The body's internal system to control the daily rhythm of the body's functions (i.e., the circadian system), the body's stress response, and the body's neurobiology are highly interconnected. Thus, the rhythm of the circadian system impacts alcohol use patterns; at the same time, alcohol drinking also can alter circadian functions. The sensitivity of the circadian system to alcohol may result from alcohol's effects on the expression of several of the clock genes that regulate circadian function. The stress response system involves the hypothalamus and pituitary gland in the brain and the adrenal glands, as well as the hormones they secrete, including corticotrophin-releasing hormone, adrenocorticotrophic hormone, and glucocorticoids. It is controlled by brain-signaling molecules, including endogenous opioids such as β-endorphin. Alcohol consumption influences the activity of this system and vice versa. Finally, interactions exist between the circadian system, the hypothalamic-pituitary-adrenal axis, and alcohol consumption. Thus, it seems that certain clock genes may control functions of the stress response system and that these interactions are affected by alcohol.

  4. Yaw dynamics of horizontal axis wind turbines

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, A.C. (Utah Univ., Salt Lake City, UT (United States))

    1992-05-01

    Designers of a horizontal axis wind turbine yaw mechanism are faced with a difficult decision. They know that if they elect to use a yaw- controlled rotor then the system will suffer increased initial cost and increased inherent maintenance and reliability problems. On the other hand, if they elect to allow the rotor to freely yaw they known they will have to account for unknown and random, though bounded, yaw rates. They will have a higher-risk design to trade-off against the potential for cost savings and reliability improvement. The risk of a yaw-free system could be minimized if methods were available for analyzing and understanding yaw behavior. The complexity of yaw behavior has, until recently, discouraged engineers from developing a complete yaw analysis method. The objectives of this work are to (1) provide a fundamental understanding of free-yaw mechanics and the design concepts most effective at eliminating yaw problems, and (2) provide tested design tools and guidelines for use by free-yaw wind systems manufacturers. The emphasis is on developing practical and sufficiently accurate design methods.

  5. On-Axis Digital Moire Optoelectronic Telemetrology

    Science.gov (United States)

    Meilan, Pablo F.; Laquidara, Aníbal P.; Bava, José A.; Garavaglia, Mario

    2008-04-01

    In previous papers [2,3,4,5] we introduced an operation based on digital moiré pattern processing to measure the distance to an object and its size. The method uses a sequence of digital photographic operations to capture two pictures of the scene with the CCD camera placed at two near and well defined positions along the optical axis of the camera. The distance ΔL between both camera positions is of the order of 1-10% of the distance L from the camera to the selected object in the scene. The teleoperation process algoritm requires to introduce ΔL to determine the distance L. Now we will report a simple and powerful optical system: an optical delay line with an optical path equal to 1.5 m, introduced in the line of sight from the camera to the selected object in the scene. With this optical system it is possible to capture the observed object at distances L and L+ΔL simultaneously in the same picture. The uncertainty in measuring L is of the order of 1%.

  6. Gut/brain axis and the microbiota.

    Science.gov (United States)

    Mayer, Emeran A; Tillisch, Kirsten; Gupta, Arpana

    2015-03-02

    Tremendous progress has been made in characterizing the bidirectional interactions between the central nervous system, the enteric nervous system, and the gastrointestinal tract. A series of provocative preclinical studies have suggested a prominent role for the gut microbiota in these gut-brain interactions. Based on studies using rodents raised in a germ-free environment, the gut microbiota appears to influence the development of emotional behavior, stress- and pain-modulation systems, and brain neurotransmitter systems. Additionally, microbiota perturbations by probiotics and antibiotics exert modulatory effects on some of these measures in adult animals. Current evidence suggests that multiple mechanisms, including endocrine and neurocrine pathways, may be involved in gut microbiota-to-brain signaling and that the brain can in turn alter microbial composition and behavior via the autonomic nervous system. Limited information is available on how these findings may translate to healthy humans or to disease states involving the brain or the gut/brain axis. Future research needs to focus on confirming that the rodent findings are translatable to human physiology and to diseases such as irritable bowel syndrome, autism, anxiety, depression, and Parkinson's disease.

  7. Effective solidity in vertical axis wind turbines

    Science.gov (United States)

    Parker, Colin M.; Leftwich, Megan C.

    2016-11-01

    The flow surrounding vertical axis wind turbines (VAWTs) is investigated using particle imaging velocimetry (PIV). This is done in a low-speed wind tunnel with a scale model that closely matches geometric and dynamic properties tip-speed ratio and Reynolds number of a full size turbine. Previous results have shown a strong dependance on the tip-speed ratio on the wake structure of the spinning turbine. However, it is not clear whether this is a speed or solidity effect. To determine this, we have measured the wakes of three turbines with different chord-to-diameter ratios, and a solid cylinder. The flow is visualized at the horizontal mid-plane as well as the vertical mid-plane behind the turbine. The results are both ensemble averaged and phase averaged by syncing the PIV system with the rotation of the turbine. By keeping the Reynolds number constant with both chord and diameter, we can determine how each effects the wake structure. As these parameters are varied there are distinct changes in the mean flow of the wake. Additionally, by looking at the vorticity in the phase averaged profiles we can see structural changes to the overall wake pattern.

  8. The microbiota-gut-brain axis and its potential therapeutic role in autism spectrum disorder.

    Science.gov (United States)

    Li, Q; Zhou, J-M

    2016-06-02

    Autism spectrum disorder (ASD) is a series of neurodevelopmental disorders that are characterized by deficits in both social and cognitive functions. Although the exact etiology and pathology of ASD remain unclear, a disorder of the microbiota-gut-brain axis is emerging as a prominent factor in the generation of autistic behaviors. Clinical studies have shown that gastrointestinal symptoms and compositional changes in the gut microbiota frequently accompany cerebral disorders in patients with ASD. A disturbance in the gut microbiota, which is usually induced by a bacterial infection or chronic antibiotic exposure, has been implicated as a potential contributor to ASD. The bidirectional microbiota-gut-brain axis acts mainly through neuroendocrine, neuroimmune, and autonomic nervous mechanisms. Application of modulators of the microbiota-gut-brain axis, such as probiotics, helminthes and certain special diets, may be a promising strategy for the treatment of ASD. This review mainly discusses the salient observations of the disruptions of the microbiota-gut-brain axis in the pathogenesis of ASD and reveals its potential therapeutic role in autistic deficits.

  9. VOLUMETRIC ERROR COMPENSATION IN FIVE-AXIS CNC MACHINING CENTER THROUGH KINEMATICS MODELING OF GEOMETRIC ERROR

    Directory of Open Access Journals (Sweden)

    Pooyan Vahidi Pashsaki

    2016-06-01

    Full Text Available Accuracy of a five-axis CNC machine tool is affected by a vast number of error sources. This paper investigates volumetric error modeling and its compensation to the basis for creation of new tool path for improvement of work pieces accuracy. The volumetric error model of a five-axis machine tool with the configuration RTTTR (tilting head B-axis and rotary table in work piece side A΄ was set up taking into consideration rigid body kinematics and homogeneous transformation matrix, in which 43 error components are included. Volumetric error comprises 43 error components that can separately reduce geometrical and dimensional accuracy of work pieces. The machining accuracy of work piece is guaranteed due to the position of the cutting tool center point (TCP relative to the work piece. The cutting tool is deviated from its ideal position relative to the work piece and machining error is experienced. For compensation process detection of the present tool path and analysis of the RTTTR five-axis CNC machine tools geometrical error, translating current position of component to compensated positions using the Kinematics error model, converting newly created component to new tool paths using the compensation algorithms and finally editing old G-codes using G-code generator algorithm have been employed.

  10. Off-axis beam dynamics in rf-gun-based electron photoinjectors

    Science.gov (United States)

    Huang, R.; Mitchell, C.; Papadopoulos, C.; Qian, H.; Venturini, M.; Qiang, J.; Filippetto, D.; Staples, J.; Jia, Q.; Sannibale, F.

    2016-11-01

    The need to operate an rf-gun-based electron photoinjector with a beam emitted away from the cathode center can occur under various circumstances. First, in some cases the cathode can be affected by ion back-bombardment that progressively reduces the quantum efficiency (QE) in its center, making off-axis operation mandatory; second, in some cases the drive laser intensity can be sufficiently high to generate QE depletion in the cathode area illuminated by the laser, forcing off-axis operation; last, in cathodes with nonuniform QE distribution it could be convenient to operate off axis to exploit a better QE. However, operation in this mode may lead to growth of the projected transverse beam emittances due to correlations between the transverse and longitudinal degrees of freedom that are introduced within the gun and downstream rf cavities. A strategy is described to mitigate this emittance growth by allowing the beam to propagate along a carefully tuned off-axis trajectory in downstream rf cavities to remove the time-dependent rf kicks introduced in the gun. Along this trajectory, short range wakefields do not degrade the emittance, and long range wakefields degrade the emittance for very high repetition rate only.

  11. Flywheel Single-Axis Integrated Momentum and Power Control System Demonstrated

    Science.gov (United States)

    Soeder, James F.

    2004-01-01

    On July 10, 2003, the NASA Glenn Research Center flywheel team experimentally demonstrated a two-flywheel-module system that simultaneously provided attitude control in a single axis and regulated power. The test was conducted using the D1 flywheel module and the high-speed shaft (HSS) in the High Energy Flywheel Facility (HEFF). Both of these flywheel modules consist of a magnetically levitated rotor with an integral motor/generator, a vacuum housing, and mechanical touchdown bearings. Energy is stored kinetically in the rotor. The motor/generator allows energy to be added to or withdrawn from the rotor, and magnetic bearings and a vacuum enclosure are used to minimize losses.

  12. Initial Test Results from a 3-axis Vibrating Ring Gyroscope

    Energy Technology Data Exchange (ETDEWEB)

    Gallacher, B J; Neasham, J A; Burdess, J S; Harris, A J [INSAT University of Newcastle upon Tyne NE1 7RU (United Kingdom)

    2006-04-01

    There are several application areas where the simultaneous measurement of rates of rotation about three mutually orthogonal axes is required. In this paper the principle features of a 3-axis vibrating ring gyroscope are described. The fabrication process for the gyroscope is presented and employs standard MEMS techniques. The modal properties for the ring are measured experimentally using laser vibrometry and electrostatic sensing and compared with the design predictions. In operation as a rate gyroscope it is necessary to excite the primary motion of the gyroscope and control is amplitude. As Q-factors of vibratory gyroscope are typically of the order 10{sup 3}-10{sup 4} slight variations in environmental conditions will perturb the natural frequency of the primary mode significantly. To ensure the primary motion of the gyroscope is maintained with constant amplitude a control scheme employing both frequency tracking and amplitude control is required. An electronic control system using digital signal processing (DSP) has been developed to ensure excitation of the primary motion occurs at resonance with controlled amplitude. The control scheme employs an embedded processor to generate the drive frequency (via a D/A converter) and to monitor the primary vibration (via an A/D converter). Experimental results from the control scheme highlighting its effectiveness over conventional PLL approaches are presented.

  13. Spin-stabilized magnetic levitation without vertical axis of rotation

    Science.gov (United States)

    Romero, Louis [Albuquerque, NM; Christenson, Todd [Albuquerque, NM; Aaronson, Gene [Albuquerque, NM

    2009-06-09

    The symmetry properties of a magnetic levitation arrangement are exploited to produce spin-stabilized magnetic levitation without aligning the rotational axis of the rotor with the direction of the force of gravity. The rotation of the rotor stabilizes perturbations directed parallel to the rotational axis.

  14. Sequence-dependent rotation axis changes in tennis.

    Science.gov (United States)

    Hansen, Clint; Martin, Caroline; Rezzoug, Nasser; Gorce, Philippe; Bideau, Benoit; Isableu, Brice

    2017-09-01

    The purpose of this study was to evaluate the role of rotation axes during a tennis serve. A motion capture system was used to evaluate the contribution of the potential axes of rotation (minimum inertia axis, shoulder-centre of mass axis and the shoulder-elbow axis) during the four discrete tennis serve phases (loading, cocking, acceleration and follow through). Ten ranked athletes (International Tennis Number 1-3) repeatedly performed a flat service aiming at a target on the other side of the net. The four serve phases are distinct and thus, each movement phase seems to be organised around specific rotation axes. The results showed that the limbs' rotational axis does not necessarily coincide with the minimum inertia axis across the cocking phase of the tennis serve. Even though individual serving strategies were exposed, all participants showed an effect due to the cocking phase and changed the rotation axis during the task. Taken together, the results showed that despite inter-individual differences, nine out of 10 participants changed the rotation axis towards the minimum inertia and/or the mass axis in an endeavour to maximise external rotation of the shoulder to optimally prepare for the acceleration phase.

  15. Wind rotor with vertical axis. Vindrotor med vertikal axel

    Energy Technology Data Exchange (ETDEWEB)

    Colling, J.; Sjoenell, B.

    1987-06-15

    This rotor is of dual type i.e. a paddle wheel shaped rotor close to the vertical axis and a second rotor consisting of vertical blades with wing profile and attached to radial spokes which are fixed to the axis together with the paddle wheel rotor. (L.F.).

  16. Divide and conquer: Segmentation and patterning of the anteroposterior axis

    NARCIS (Netherlands)

    Peres, João Nuno Borges Baptista

    2005-01-01

    The formation of the anteroposterior (AP) axis is one of the key events that occur during embryogenesis. Here we investigate the dual processes of patterning and segmentation of the AP axis. To study the role of Hox genes in AP patterning, we decided to analyse the function of the PG1 (paralogous

  17. Verticality Perception During Off-Vertical Axis Rotation

    NARCIS (Netherlands)

    Vingerhoets, R.A.A.; Gisbergen, J.A.M. van; Medendorp, W.P.

    2007-01-01

    During prolonged rotation about a tilted yaw axis, often referred to as off-vertical axis rotation (OVAR), a percept of being translated along a conical path slowly emerges as the sense of rotation subsides. Recently, we found that these perceptual changes are consistent with a canal-otolith interac

  18. Verticality perception during off-vertical axis rotation

    NARCIS (Netherlands)

    Vingerhoets, R.A.A.; Gisbergen, J.A.M. van; Medendorp, W.P.

    2007-01-01

    During prolonged rotation about a tilted yaw axis, often referred to as off-vertical axis rotation (OVAR), a percept of being translated along a conical path slowly emerges as the sense of rotation subsides. Recently, we found that these perceptual changes are consistent with a canal-otolith interac

  19. Angular momentum projection of tilted axis rotating states

    Energy Technology Data Exchange (ETDEWEB)

    Oi, M.; Onishi, N.; Tajima, N. [Tokyo Univ. (Japan); Horibata, T.

    1998-03-01

    We applied an exact angular momentum projection to three dimensional cranked HFB (3d-CHFB) states. Tilted axis rotating states (TAR) and principal axis rotating states (PAR) are compared. It is shown that TAR is more adequate than PAR for description of the back bending phenomena driven by tilted rotation or wobbling motion. (author)

  20. Turbulence in vertical axis wind turbine canopies

    Science.gov (United States)

    Kinzel, Matthias; Araya, Daniel B.; Dabiri, John O.

    2015-11-01

    Experimental results from three different full scale arrays of vertical-axis wind turbines (VAWTs) under natural wind conditions are presented. The wind velocities throughout the turbine arrays are measured using a portable meteorological tower with seven, vertically staggered, three-component ultrasonic anemometers. The power output of each turbine is recorded simultaneously. The comparison between the horizontal and vertical energy transport for the different turbine array sizes shows the importance of vertical transport for large array configurations. Quadrant-hole analysis is employed to gain a better understanding of the vertical energy transport at the top of the VAWT arrays. The results show a striking similarity between the flows in the VAWT arrays and the adjustment region of canopies. Namely, an increase in ejections and sweeps and decrease in inward and outward interactions occur inside the turbine array. Ejections are the strongest contributor, which is in agreement with the literature on evolving and sparse canopy flows. The influence of the turbine array size on the power output of the downstream turbines is examined by comparing a streamwise row of four single turbines with square arrays of nine turbine pairs. The results suggest that a new boundary layer forms on top of the larger turbine arrays as the flow adjusts to the new roughness length. This increases the turbulent energy transport over the whole planform area of the turbine array. By contrast, for the four single turbines, the vertical energy transport due to turbulent fluctuations is only increased in the near wake of the turbines. These findings add to the knowledge of energy transport in turbine arrays and therefore the optimization of the turbine spacing in wind farms.

  1. Shot H3837: Darht's First Dual-Axis Explosive Experiment

    Science.gov (United States)

    Mendez, Jacob; McNeil, Wendy Vogan; Harsh, James; Hull, Lawrence

    2011-06-01

    Test H3837 was the first explosive shot performed in front of both flash x-ray axes at the Los Alamos Dual Axis Radiographic HydroTest (DARHT) facility. Executed in November 2009, the shot was an explosively-driven metal flyer plate in a series of experiments designed to explore equation-of-state properties of shocked materials. Imaging the initial shock wave traveling through the flyer plate, DARHT Axis II captured the range of motion from the shock front emergence in the flyer to breakout at the free surface; the Axis I pulse provided a perpendicular perspective of the shot at a time coinciding with the third pulse of Axis II. Since the days of the Manhattan Project, penetrating radiography with multiple frames from different viewing angles has remained a high-profile goal at the Laboratory. H3837 is merely the beginning of a bright future for two-axis penetrating radiography.

  2. DARHT status and preparations for dual-axis hydrotesting (u)

    Energy Technology Data Exchange (ETDEWEB)

    Bowman, David W [Los Alamos National Laboratory

    2010-01-01

    The status of the DARHT facility, including a history of events that have taken place since the end of the DARHT Second Axis Refurbishment Project, is discussed. Technical and operational enhancements that have been made will be addressed, and recent technical challenges, such as the RF noise in the kicker region, are discussed. Historical data on reliability of the second axis is discussed, as well as operational changes made to enhance reliability. In addition, the path forward for integrating the second axis into overall DARHT operations in preparation for a hydrotest is addressed. Timing integration tests are accompanied by a series of tests to evaluate neutron contamination and cross-axis scatter, with attempts being made to provide adequate shielding to minimize the effects of neutrons and cross-beam scatter. The discussion includes results of the testing performed to-date, and concludes with a discussion of the path forward for dual-axis hydrotesting at DARHT.

  3. ACCURATE MEASUREMENT OF ROTA-RY MACHINE AXIS CENTER TRACE

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Four methods aiming at measuring rotary machine axis center trace are discussed in detail.The comparative analysis is made on some aspects such as measurement accuracy, on-machine characteristics, feasibility, practical operation convenience and the integrity of measurement information.In order to simplify measurement, the axis profile error is ignored in traditional condition, while the measurement accuracy will be reduced.The 3-point method that the axis profile error is firstly separated has better real time character, at the same time, not only the axis motion error but also the axis profile error can be measured.All of those information can be used to diagnose the fault origin.The analysis result is proved to be correct by the experiment.

  4. Properties and crystallization phenomena in Li2Si2O5-Ca5(PO43F and Li2Si2O5-Sr5(PO43F glass-ceramics via twofold internal crystallization

    Directory of Open Access Journals (Sweden)

    Markus eRampf

    2015-09-01

    Full Text Available The combination of specific mechanical, esthetic and chemical properties is decisive for the application of materials in prosthodontics. Controlled twofold crystallization provides a powerful tool to produce special property combinations for glass-ceramic materials. The present study outlines the potential of precipitating Ca5(PO43F as well as Sr5(PO43F as minor crystal phases in Li2Si2O5 glass-ceramics. Base glasses with different contents of CaO/SrO, P2O5 and F- were prepared within the glasses of the SiO2-Li2O-K2O-CaO/SrO-Al2O3-P2O5 system. Preliminary studies of nucleation by means of XRD and SEM of the nucleated base glasses revealed X-ray amorphous phase separation phenomena. Qualitative and quantitative crystal phase analyses after crystallization were conducted using XRD in combination with Rietveld refinement. As a main result, a direct proportional relationship between the content of apatite-forming components in the base glasses and the content of apatite in the glass ceramics was established. The microstructures of the glass-ceramics were investigated using SEM. Microstructural and mechanical properties were found to be dominated by Li2Si2O5 crystals and quite independent of the content of the apatite present in the glass-ceramics. Biaxial strengths of up to 540 MPa were detected. Ca5(PO43F and Sr5(PO43F influence the translucency of the glass-ceramics and hence, help to precisely tailor the properties of Li2Si2O5 glass-ceramics. The authors conclude that the twofold crystallization of Li2Si2O5-Ca5(PO43F or Li2Si2O5-Sr5(PO43F glass-ceramics involves independent solid state reactions which can be controlled via the chemical composition of the base glasses. The influence of the minor apatite phase on the optical properties helps to achieve new combinations of features of the glass-ceramics and hence, displays new potential for dental applications.

  5. Properties and Crystallization Phenomena in Li2Si2O5-Ca5(PO4)3F and Li2Si2O5-Sr5(PO4)3F Glass-Ceramics Via Twofold Internal Crystallization.

    Science.gov (United States)

    Rampf, Markus; Dittmer, Marc; Ritzberger, Christian; Schweiger, Marcel; Höland, Wolfram

    2015-01-01

    The combination of specific mechanical, esthetic, and chemical properties is decisive for the application of materials in prosthodontics. Controlled twofold crystallization provides a powerful tool to produce special property combinations for glass-ceramic materials. The present study outlines the potential of precipitating Ca5(PO4)3F as well as Sr5(PO4)3F as minor crystal phases in Li2Si2O5 glass-ceramics. Base glasses with different contents of CaO/SrO, P2O5, and F(-) were prepared within the glasses of the SiO2-Li2O-K2O-CaO/SrO-Al2O3-P2O5-F system. Preliminary studies of nucleation by means of XRD and scanning electron microscopy (SEM) of the nucleated base glasses revealed X-ray amorphous phase separation phenomena. Qualitative and quantitative crystal phase analyses after crystallization were conducted using XRD in combination with Rietveld refinement. As a main result, a direct proportional relationship between the content of apatite-forming components in the base glasses and the content of apatite in the glass-ceramics was established. The microstructures of the glass-ceramics were investigated using SEM. Microstructural and mechanical properties were found to be dominated by Li2Si2O5 crystals and quite independent of the content of the apatite present in the glass-ceramics. Biaxial strengths of up to 540 MPa were detected. Ca5(PO4)3F and Sr5(PO4)3F influence the translucency of the glass-ceramics and, hence, help to precisely tailor the properties of Li2Si2O5 glass-ceramics. The authors conclude that the twofold crystallization of Li2Si2O5-Ca5(PO4)3F or Li2Si2O5-Sr5(PO4)3F glass-ceramics involves independent solid-state reactions, which can be controlled via the chemical composition of the base glasses. The influence of the minor apatite phase on the optical properties helps to achieve new combinations of features of the glass-ceramics and, hence, displays new potential for dental applications.

  6. 2T/5T Two-Axis Cryogen Free Superconducting Vector Magnet With Variable Temperature Space

    Science.gov (United States)

    Demikhov, E. I.; Demikhov, T. E.; Kostrov, E. A.; Lysenko, V. V.; Piskunov, N. A.

    2014-05-01

    A conduction cooled 2T / 5T superconducting vector magnetic system with a variable temperature space was developed and tested. The system is based on a commercial two-stage 4 K Gifford-McMahon cryocooler with the cooling power of 1.5 W at 4.2 K. The cool down time of the magnet from room temperature to 3.2 K is 17 hours. The system provides sample temperature range of 6.0-300 K. The clear diameter of variable temperature space is 39 mm. A 5 T solenoid generates magnetic field in the vertical axis and a 2 T split coil generates field in the horizontal axis. The magnets are made of niobium-titanium wire wound on a copper former. A PC controlled rotary drive is applied to rotate a sample holder around the vertical axis. Thus the measured sample can be exposed to the magnetic field in any desired direction. A helium gas gap heat switch is used as a controllable thermal link between the variable temperature space and the 2nd stage to avoid overheating of the magnet at high temperatures of the sample. The system design, manufacturing and test results are presented.

  7. Investigation of the Z-axis resolution of breast tomosynthesis mammography systems

    Science.gov (United States)

    Zhang, Yiheng; Chan, Heang-Ping; Sahiner, Berkman; Wei, Jun; Ge, Jun; Hadjiiski, Lubomir M.; Zhou, Chuan

    2007-03-01

    Digital Tomosynthesis Mammography (DTM) is a promising modality that can improve breast cancer detection. DTM acquires low-dose mammograms at a number of projection angles over a limited angular range and reconstructs the 3D breast volume. DTM can provide depth information to separate overlapping breast tissues occurred in conventional mammograms, thereby facilitating detection of subtle lesions. In this work, we investigated the impact of the imaging parameters and reconstruction methods on the Z-axis resolution in DTM systems. The Z-axis resolution represents the ability of the DTM system to distinguish adjacent objects along the depth direction. A DTM system with variable image acquisition parameters was modeled. In this preliminary study, a computer phantom containing a high-density point object embedded in an air volume was used. We simulated a range of DTM conditions by generating an appropriate number of PV images in 3° increments covering a total tomosynthesis angle from +/-15° to +/-30°. The Simultaneous Algebraic Reconstruction Technique (SART) was used for reconstruction of the imaged volume from the noise-free projection data and the results were compared to those of back-projection method. Vertical line profiles along the Z-axis and through the object center were extracted from the reconstructed volume and the full-width-at-half-maximum (FWHM) of the normalized intensity profile was used to evaluate the Z-axis resolution. Preliminary results demonstrated that while the Z-axis resolution remains almost constant as a function of depth within a 5-cm-thick volume, it is strongly affected by the PV angular range such that the depth resolution improves with increasing total tomosynthesis angle. The depth resolution also depends on the reconstruction algorithm employed; the SART method is superior to the simple back-projection method in terms of depth resolution.

  8. AxiSketcher: Interactive Nonlinear Axis Mapping of Visualizations through User Drawings.

    Science.gov (United States)

    Kwon, Bum Chul; Kim, Hannah; Wall, Emily; Choo, Jaegul; Park, Haesun; Endert, Alex

    2017-01-01

    Visual analytics techniques help users explore high-dimensional data. However, it is often challenging for users to express their domain knowledge in order to steer the underlying data model, especially when they have little attribute-level knowledge. Furthermore, users' complex, high-level domain knowledge, compared to low-level attributes, posits even greater challenges. To overcome these challenges, we introduce a technique to interpret a user's drawings with an interactive, nonlinear axis mapping approach called AxiSketcher. This technique enables users to impose their domain knowledge on a visualization by allowing interaction with data entries rather than with data attributes. The proposed interaction is performed through directly sketching lines over the visualization. Using this technique, users can draw lines over selected data points, and the system forms the axes that represent a nonlinear, weighted combination of multidimensional attributes. In this paper, we describe our techniques in three areas: 1) the design space of sketching methods for eliciting users' nonlinear domain knowledge; 2) the underlying model that translates users' input, extracts patterns behind the selected data points, and results in nonlinear axes reflecting users' complex intent; and 3) the interactive visualization for viewing, assessing, and reconstructing the newly formed, nonlinear axes.

  9. Family resemblance in fat intake, nutrition attitudes and beliefs : a study among three generations of women

    NARCIS (Netherlands)

    Stafleu, A.

    1994-01-01

    In this thesis nutrition attitudes, beliefs, and fat intake in three generations of women are described. The aim of the study was twofold: the development of methods, and to study family resemblance in food habits. Based on literature study and qualitative pilot studies a questionnaire on

  10. Family resemblance in fat intake, nutrition attitudes and beliefs: a study among three generations of women.

    NARCIS (Netherlands)

    Stafleu, A.

    1994-01-01

    In this thesis nutrition attitudes, beliefs, and fat intake in three generations of women are described. The aim of the study was twofold: the development of methods, and to study family resemblance in food habits. Based on literature study and qualitative pilot studies a questionnaire on beliefs an

  11. Self-Generated Goals and Goal Process Appraisals: Relationships with Sociodemographic Factors and Well-Being

    Science.gov (United States)

    Massey, Emma K.; Gebhardt, Winifred A.; Garnefski, Nadia

    2009-01-01

    In this study the full array of personal goals pursued by adolescents was examined using an idiographic goal-elicitation procedure. The aims of the study were twofold. Firstly, we investigated individual differences in self-generated goals and goal process appraisals based on sociodemographic characteristics. Secondly, we investigated the…

  12. Role of peroxidase activity and Ca(2+) in axis growth during seed germination.

    Science.gov (United States)

    Singh, Khangembam L; Chaudhuri, Abira; Kar, Rup K

    2015-10-01

    Axis growth during seed germination is mediated by reactive oxygen species and apoplastic peroxidase plays a role by producing OH(·) from H2O2. Ca (2+) activates both apoplastic peroxidase and NADPH oxidase. Role of reactive oxygen species (ROS) in seed germination and axis growth has been demonstrated in our earlier works with Vigna radiata seeds by studying superoxide generation and its metabolism in axes (Singh et al. in Plant Signal Behav doi: 10.4161/psb.29278 , 2014). In the present study, the participation of apoplastic peroxidase along with the involvement of Ca(2+) in axis growth during germination and post-germination stage has been investigated. Pharmacological studies using peroxidase (POX) inhibitors (salicylhydroxamic acid, SHAM; sodium azide, NaN3) and OH(·) scavenger (sodium benzoate, NaBz) indicated that seed germination and early axis growth (phase I) depend much on POX activity. Subapical region of axes corresponding to radicle that elongated much particularly in phase II suggested high POX activity as well as high NADPH oxidase (Respiratory burst oxidase homologue, Rboh, in plants) activity as indicated from localization by staining with TMB (3,3',5,5'-tetramethyl benzidine dihydrochloride hydrate) and NBT (nitroblue tetrazolium chloride), respectively. Apoplastic class III peroxidase (Prx) and also cellular POX activity reached maximum at the time of radicle emergence as revealed by TMB staining, spectrophotometric and in-gel assay for POX activity. Treatment with Ca(2+) antagonists (La(3+), plasma membrane-located Ca(2+) channel blocker and EGTA, Ca(2+) chelator in apoplast) retarded seed germination and strongly inhibited axis growth, while Li(+) (blocks endosomal Ca(2+) release) was effective only in retarding phase II axis growth suggesting an involvement of Ca(2+) influx during early axis growth. From the effect of Ca(2+) antagonists on the localization of activities of POX and Rboh using stains, it appears that Ca(2+) plays a dual role

  13. On the problems of describing joint axis alignment.

    Science.gov (United States)

    Ball, Kevin A; Greiner, Thomas M

    2008-01-01

    Each three-dimensional joint possesses at least one potentially oblique axis of rotation. Several systems are used to express joint axis alignment. One system, designated the plane projection (PP) method, describes angles based on orthogonal projections onto two, of the three, anatomical planes. Alternatively, a joint axis may be described in two different ways using two sequential Cardan angle rotations. These expression systems all lay claim to similar descriptive labels, such as deviation and elevation. Difficulties arise as researchers use these various methods to compare their own data to the results of others. A joint axis alignment, described as 27 degrees deviation and 41 degrees elevation in PP, differs by as much as 6 degrees when expressed as Cardan angles. Differences among expression systems increase as the joint axis alignment becomes more oblique -- eventually differing by as much as 75 degrees . This paper explores implications for this lack of congruence among the joint axis expression systems. Effective steps in dealing with these issues begin with recognizing the existence and extent of the problem. The paper provides a common set of algorithms to illustrate and alleviate the possible problems associated with the exchange of joint axis alignment data.

  14. Childhood stressful events, HPA axis and anxiety disorders.

    Science.gov (United States)

    Faravelli, Carlo; Lo Sauro, Carolina; Godini, Lucia; Lelli, Lorenzo; Benni, Laura; Pietrini, Francesco; Lazzeretti, Lisa; Talamba, Gabriela Alina; Fioravanti, Giulia; Ricca, Valdo

    2012-02-22

    Anxiety disorders are among the most common of all mental disorders and their pathogenesis is a major topic in psychiatry, both for prevention and treatment. Early stressful life events and alterations of hypothalamic pituitary adrenal (HPA) axis function seem to have a significant role in the onset of anxiety. Existing data appear to support the mediating effect of the HPA axis between childhood traumata and posttraumatic stress disorder. Findings on the HPA axis activity at baseline and after stimuli in panic disordered patients are inconclusive, even if stressful life events may have a triggering function in the development of this disorder. Data on the relationship between stress, HPA axis functioning and obsessive-compulsive disorder (OCD) are scarce and discordant, but an increased activity of the HPA axis is reported in OCD patients. Moreover, normal basal cortisol levels and hyper-responsiveness of the adrenal cortex during a psychosocial stressor are observed in social phobics. Finally, abnormal HPA axis activity has also been observed in generalized anxiety disordered patients. While several hypothesis have attempted to explain these findings over time, currently the most widely accepted theory is that early stressful life events may provoke alterations of the stress response and thus of the HPA axis, that can endure during adulthood, predisposing individuals to develop psychopathology. All theories are reviewed and the authors conclude that childhood life events and HPA abnormalities may be specifically and transnosographically related to all anxiety disorders, as well as, more broadly, to all psychiatric disorders.

  15. Off-axis illumination direct-to-digital holography

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, Clarence E.; Price, Jeffery R.; Voelkl, Edgar; Hanson, Gregory R.

    2004-06-08

    Systems and methods are described for off-axis illumination direct-to-digital holography. A method of recording an off-axis illuminated spatially heterodyne hologram including spatially heterodyne fringes for Fourier analysis, includes: reflecting a reference beam from a reference mirror at a non-normal angle; reflecting an object beam from an object at an angle with respect to an optical axis defined by a focusing lens; focusing the reference beam and the object beam at a focal plane of a digital recorder to form the off-axis illuminated spatially heterodyne hologram including spatially heterodyne fringes for Fourier analysis; digitally recording the off-axis illuminated spatially heterodyne hologram including spatially heterodyne fringes for Fourier analysis; Fourier analyzing the recorded off-axis illuminated spatially heterodyne hologram including spatially heterodyne fringes by transforming axes of the recorded off-axis illuminated spatially heterodyne hologram including spatially heterodyne fringes in Fourier space to sit on top of a heterodyne carrier frequency defined as an angle between the reference beam and the object beam; applying a digital filter to cut off signals around an original origin; and then performing an inverse Fourier transform.

  16. Single-Axis Three-Beam Amplitude Monopulse Antenna-Signal Processing Issues

    Energy Technology Data Exchange (ETDEWEB)

    Doerry, Armin W. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Bickel, Douglas L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-05-01

    Typically, when three or more antenna beams along a single axis are required, the answer has been multiple antenna phase-centers, essentially a phase-monopulse system. Such systems and their design parameters are well-reported in the literature. Less appreciated is that three or more antenna beams can also be generated in an amplitude-monopulse fashion. Consequently, design guidelines and performance analysis of such antennas is somewhat under-reported in the literature. We provide discussion herein of three beams arrayed in a single axis with an amplitude-monopulse configuration. Acknowledgements The preparation of this report is the result of an unfunded research and development activity. Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administ ration under contract DE-AC04-94AL85000.

  17. Sun-Relative Pointing for Dual-Axis Solar Trackers Employing Azimuth and Elevation Rotations

    Energy Technology Data Exchange (ETDEWEB)

    Riley, Daniel [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Hansen, Clifford W. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2014-12-30

    Dual axis trackers employing azimuth and elevation rotations are common in the field of photovoltaic (PV) energy generation. Accurate sun-tracking algorithms are widely available. However, a steering algorithm has not been available to accurately point the tracker away from the sun such that a vector projection of the sun beam onto the tracker face falls along a desired path relative to the tracker face. We have developed an algorithm which produces the appropriate azimuth and elevation angles for a dual axis tracker when given the sun position, desired angle of incidence, and the desired projection of the sun beam onto the tracker face. Development of this algorithm was inspired by the need to accurately steer a tracker to desired sun-relative positions in order to better characterize the electro-optical properties of PV and CPV modules.

  18. An Experimental Investigation of Passive Variable-Pitch Vertical-Axis Ocean Current Turbine

    Directory of Open Access Journals (Sweden)

    Ridho Hantoro

    2011-04-01

    Full Text Available Vertical-axis hydrokinetic turbines with fixed pitch blades typically suffer from poor starting torque, low efficiency and shaking due to large fluctuations in both radial and tangential force with azimuth angle. Maximizing the turbine power output can be achieved only if the mechanism of generation of the hydrodynamic force on the blades is clearly identified and tools to design high-performance rotors are developed. This paper describes an initial experimental investigation to understand more of the performance on vertical-axis turbine related to the effect of fixed-pitch and passive variable-pitch application using airfoil NACA 0018. Comparative analysis according to aspects of rotation and tip speed ratios was discussed. Information regarding the changes of foil position in passive variable-pitch during rotation at a limited range of flow velocity variations test was obtained and analyzed.

  19. Direct calculation of acceleration field through homogeneous transformation for two-axis centrifuge

    Institute of Scientific and Technical Information of China (English)

    吴广玉; 任顺清; 陈希军

    2003-01-01

    A precision centrifuge is an inertial navigation test equipment used for calibrating the characteristicsof accelerometers with high overloading, and a two-axis centrifuge can be used to generate either constant accel-eration or harmonic acceleration. The moving trajectory equation about the origin of the accelerometer coordinatesystem in a two-axis centrifuge was directly deduced through homogeneous transformation. The acceleration vec-tor of the origin in accelerometer coordinate system was achieved by making the second derivative of this trajec-tory equation. The acceleration components were acquired by decomposing this acceleration vector along thethree axes of the accelerometer coordinate system. The correctness of the homogeneous transformation was veri-fied through vector analysis.

  20. Note: Leaf undulator to realize polarization control with low on-axis heat load.

    Science.gov (United States)

    Yan, J; Qiao, S

    2010-05-01

    Here, a new operational mode of an electromagnetic elliptical undulator, called leaf undulator, is proposed and studied. It can provide linearly polarized radiation at an arbitrary polarization direction depending on the magnitude and polarity of the horizontal and vertical magnetic fields. The polarization direction becomes 45 degrees when the horizontal and vertical magnetic fields are equal in strength. It is also able to switch the operational mode to purely circular or elliptical one. To lower the on-axis power density generated by undulators operating in linear mode, different designs have been presented in the past. Leaf undulator can suppress the on-axis power density by an order of magnitude compared to the so-called Knot and Figure-8 undulators, while maintaining comparable photon flux of the fundamental harmonic. Furthermore, it is possible to reach a lower fundamental energy under linear mode than by any other design using comparable magnetic field strengths.

  1. Interferometric phase microscopy using slightly-off-axis reflective point diffraction interferometer

    Science.gov (United States)

    Bai, Hongyi; Zhong, Zhi; Shan, Mingguang; Liu, Lei; Guo, Lili; Zhang, Yabin

    2017-03-01

    An interferometric phase microscopy (IPM) is proposed using slightly-off-axis reflective point diffraction interferometry for quantitative phase imaging. A retro-reflector consisting two mirrors is used to generate an angle between the object beam and reference beam, and a 45° tilted polarizing beam splitter is used to split the horizontal and vertical components of the both beams. Two carrier interferograms with π/2 phase-shift can be acquired in one shot, and the phase distribution of a thin specimen can be retrieved using a fast reconstruction method. The new IPM without loss in the utilization of the input-plane field of view combines the real time and optimizing detector bandwidth measurement benefit associated with slightly-off-axis method, high stability associated with common path geometry, and simplicity in terms of procedure and setup. Experiments are carried out on both static and dynamic specimens to demonstrate the validity and stability of the proposed method.

  2. Simultaneous two-wavelength phase unwrapping using an external module for multiplexing off-axis holography.

    Science.gov (United States)

    Turko, Nir A; Shaked, Natan T

    2017-01-01

    We present a dual-wavelength external holographic microscopy module for quantitative phase imaging of 3D structures with extended thickness range. This is done by simultaneous acquisition of two off-axis interferograms, each at a different wavelength, and generation of a synthetic wavelength, which is larger than the sample optical thickness, allowing two-wavelength unwrapping. The simultaneous acquisition is carried out by using optical multiplexing of the two interferograms onto the camera, where each of them has orthogonal off-axis interference fringe direction in relation to the other one. We used the system to quantitatively image a 7.96 μm step target and 30.5 μm circular copper pillars.

  3. Sirt1-Sirt3 axis regulates human blood-brain barrier permeability in response to ischemia.

    Science.gov (United States)

    Chen, Tao; Dai, Shu-Hui; Li, Xia; Luo, Peng; Zhu, Jie; Wang, Yu-Hai; Fei, Zhou; Jiang, Xiao-Fan

    2017-09-22

    Sirtuin1 (Sirt1) and Sirtuin3 (Sirt3) are two well-characterized members of the silent information regulator 2 (Sir2) family of proteins. Both Sirt1 and Sirt3 have been shown to play vital roles in resistance to cellular stress, but the interaction between these two sirtuins has not been fully determined. In this study, we investigated the role of Sirt1-Sirt3 axis in blood-brain barrier (BBB) permeability after ischemia in vitro. Human brain microvascular endothelial cells and astrocytes were co-cultured to model the BBB in vitro and oxygen and glucose deprivation (OGD) was performed to mimic ischemia. The results of transepithelial electrical resistance (TEER) showed that suppression of Sirt1 via siRNA or salermide significantly decreased BBB permeability, whereas Sirt3 knockdown increased BBB permeability. In addition, Sirt1 was shown to regulate Sirt3 expression after OGD through inhibiting the AMPK-PGC1 pathway. Application of the AMPK inhibitor compound C partially prevented the effects of Sirt1-Sirt3 axis on BBB permeability after OGD. The results of flow cytometry and cytochrome c release demonstrated that Sirt1 and Sirt3 exert opposite effects on OGD-induced apoptosis. Furthermore, suppression of Sirt1 was shown to attenuate mitochondrial reactive oxygen species (ROS) generation, which contribute to the Sirt1-Sirt3 axis-induced regulation of BBB permeability and cell damage. In summary, these findings demonstrate that the Sirt1-Sirt3 axis might act as an important modulator in BBB physiology, and could be a therapeutic target for ischemic stroke via regulating mitochondrial ROS generation. Copyright © 2017. Published by Elsevier B.V.

  4. Thoughts on the so-called radius-capitellum axis

    Energy Technology Data Exchange (ETDEWEB)

    Schild, H.; Mueller, H.A.; Wagner, H.; Baetz, W.

    1982-02-01

    We have studied 438 patients radiologically in order to observe the so-called 'radius-capitellum axis'. In about a quarter of people with normal elbows the axis passes lateral to the middle portion of the capitellum, so that even when there is marked deviation, there is no certainty that the humero-radial joint is abnormal. Deviation of the axis can be caused by changes in the shape of the capitellum or of the radius, or by distension of the capsule of the elbow joint, or by various changes in muscular pull.

  5. Research of the micromechanical three-axis accelerometer

    Science.gov (United States)

    Konoplev, B.; Lysenko, I.; Ryndin, E.; Ezhova, O.; Bondarev, F.

    2016-12-01

    In the report the linear acceleration sensor design with three axis of sensitivity is researched. Parameterized geometry and finite element model for modal analysis are developed in the ANSYS program. Behavioral description of the study design is developed with language VHDL-AMS to simulate the sensor operation under the influence of linear acceleration along three axis of sensitivity. On the basis of research results three-axis device sensitivity, cross-sensitivity, duration transients are specified. As part of the work the experimental sensor prototypes are fabricated.

  6. MeV electrons accelerated backward along laser axis from low energy, high intensity laser-water interactions

    CERN Document Server

    Feister, Scott; Morrison, John T; Frische, Kyle D; Orban, Chris; Ngirmang, Gregory; Handler, Abraham; Schillaci, Mark; Chowdhury, Enam A; Freeman, R R; Roquemore, W M

    2015-01-01

    Direct electron spectrum measurements show MeV energy electrons generated backward along the laser axis by a $\\lambda =$ 780 nm, 40 fs, 2.9 mJ short-pulse laser ($1.5 \\cdot 10^{18}$ W/cm$^2$). Electrons pass through a 3 mm hole in the center of the final off-axis paraboloid (OAP) and are characterized by a magnetic spectrometer. The charge collected at the OAP is hundreds of pC per pulse. A mechanism for this super-ponderomotive backward electron acceleration is discussed in the framework of 3D Particle-in-cell simulations.

  7. Fabrication technique for the production of on- and off-axis conic surfaces of revolution (WAGNER)

    Science.gov (United States)

    Faehnle, Oliver W.; van Brug, Hedser H.; Frankena, Hans J.

    1997-11-01

    A new fabrication technique, derived from an earlier development to produce on- and off-axis optical surfaces of revolution is presented. Although based on a shape copying method, it is possible to generate different types of surfaces with the same machine tool. Load controlled point- contact machining is applied using a small tool which is guided along a pre-determined tool-path, not requiring an in-process tool-path control. This fabrication technique employs a self-correcting process and is characterized by an advantageous error propagation between tool and workpiece. The characteristics of this fabrication technique are discussed together with its application for the generation of on- and off-axis surfaces with conic sections as generators. The design of a first set-up for production of conic surfaces is presented with which it is possible to generate all kinds of conic surfaces on the same machine, featuring a pantograph enabling the production of different scales of the surfaces, together with the discussion of fist experimental data.

  8. Hydrothermal Cooling Within the Lau Integrated Study Site: No Evidence for Off-axis Discharge

    Science.gov (United States)

    Baker, E. T.; Resing, J. A.; Martinez, F.; Walker, S. L.; Buck, N.; Edwards, M. H.; Nakamura, K.

    2008-12-01

    Decades of intensive hydrothermal surveying, overwhelmingly concentrated within hundreds of meters of the axes of ridge crests, has supported the view that discrete fluid discharge is predominantly concentrated in this same region. This simple view, however, conflicts with emerging evidence for a crustal high-temperature, low-velocity volume (LVV) that extends 2-3 km beyond the ridge crest and generates strongly focused hydrothermal cooling along its off-axis vertical boundaries. In March/April 2008, we used high-resolution sampling of near-bottom waters along 175 km of the hydrothermally active Valu Fa Ridge (VFR) and Eastern Lau Spreading Center (ELSC) to comprehensively test the hypothesis that hydrothermal discharge is predominantly near-axis. Our sampling array included a suite of Miniature Autonomous Plume Recorders (temperature, light scattering, oxidation-reduction potential (ORP)) attached above (to a nominal altitude of 400 m) and below the deep-towed IMI120 sonar, plus CTDs and sensors at the bottom of the string (50 m) and on the clump weight (120 m). The ELSC between 19.9° and 21°S (spreading ~80 mm/yr) grades from a broad, flat valley in the north to a shallow high in the south. Ten survey lines at 1 km spacing were centered on the axis, plus five interleaved lines around the axial high of the ABE vent field (1300 km of track). The VFR from 21.9° to 22.4°S (~50 mm/yr) is a sharp ridge that deepens ~200 m within 1 km of the axis. Seven survey lines were run at 0.7 km spacing, plus two shorter lines adjacent to a broad overlapping spreading center (390 km). CTD tows and casts supplemented the IMI120 surveys. The surveys detected emissions from the several known on-axis vent fields, and also identified a substantial unexplored field near 20.65°S, ~10 km north of the ABE field. In neither survey area, however, did we detect evidence of high-temperature discharge beyond the near-axis (±1 km) zone. Because off-axis discharge may be largely low

  9. Off-axis dose distribution for rectangle proton beam

    Institute of Scientific and Technical Information of China (English)

    Gou Cheng-Jun; Luo Zheng-Ming; Huang Chu-Ye; Feng Xiao-Ning; Wu Zhang-Wen

    2008-01-01

    This paper modifies an analytical algorithm originally developed for electron dose calculations to evaluate the off-axis dose distribution of rectangle proton beam. This spatial distribution could be described by Fermi-Eyges theory since a proton undergoes small-angle scattering when it passes through medium. Predictions of the algorithm for relative off-axis dose distribution by a 6 cm 6 cm initial monoenergetic proton beam are compared with the results from the published Monte Carlo simulations. The excellent levcl of agreement between the results of these two methods of dose calculation (< 2%) demonstrates that the off-axis dose distribution from rectangle proton beam may be computed with high accuracy using this algorithm. The results also prompts the necessity to consider the off-axis distribution when the proton is applied to clinical radiotherapy since the penumbra is significant at the distal of its range (about 0.6 cm at the Bragg-peak depth).

  10. Space/Flight Operable Miniature Six Axis Transducer Project

    Data.gov (United States)

    National Aeronautics and Space Administration — FUTEK will fully design and manufacture a sensor capable of measuring forces in and about each axis. The unit will measure forces up to 300 Newton's in the principle...

  11. The effects of lateral head tilt on ocular astigmatic axis

    Directory of Open Access Journals (Sweden)

    Hamid Fesharaki

    2014-01-01

    Conclusion: Any minimal angle of head tilt may cause erroneous measurement of astigmatic axis and should be avoided during refraction. One cannot rely on the compensatory function of ocular counter-torsion during the refraction.

  12. Determination of Elastic Twist in Horizontal Axis Wind Turbines (HAWTs)

    Energy Technology Data Exchange (ETDEWEB)

    Stoddard, F.; Nelson, V.; Starcher, K.; Andrews, B.

    2006-06-01

    This report presents the results of a project at the Alternative Energy Institute (AEI) which measured and calculated the elastic twist of three representative composite horizontal-axis blades: Carter 300, Gougeon ESI 54, and UTRC 8 kW.

  13. design and implementation of a microcontroller based dual axis ...

    African Journals Online (AJOL)

    user

    DESIGN AND IMPLEMENTATION OF A MICROCONTROLLER BASED. DUAL AXIS .... Output mechanical transducer (Servo Motor). 2.1 Power .... Fig 5: Servo Motor Algorithm. Figure 6: .... Optimization and Performance Evaluation of a Single.

  14. The infrared bands Pechan prism axis parallel detection method

    Science.gov (United States)

    Qiang, Hua; Ji, Ming; He, Yu-lan; Wang, Nan-xi; Chang, Wei-jun; Wang, Ling; Liu, Li

    2017-02-01

    In this paper, we put forward a new method to adjust the air gap of the total reflection air gap of the infrared Pechan prism. The adjustment of the air gap in the air gap of the Pechan prism directly affects the parallelism of the optical axis, so as to affect the consistency of the optical axis of the infrared system. The method solves the contradiction between the total reflection and the high transmission of the infrared wave band, and promotes the engineering of the infrared wave band. This paper puts forward the method of adjusting and controlling, which can ensure the full reflection and high penetration of the light, and also can accurately measure the optical axis of the optical axis of the different Pechan prism, and can achieve the precision of the level of the sec. For Pechan prism used in the infrared band image de rotation, make the product to realize miniaturization, lightweight plays an important significance.

  15. Asteroid spin-axis longitudes from the Lowell Observatory database

    CERN Document Server

    Bowell, E; Wasserman, L H; Muinonen, K; Penttilä, A; Trilling, D E

    2013-01-01

    By analyzing brightness variation with ecliptic longitude and using the Lowell Observatory photometric database, we estimate spin-axis longitudes for more than 350 000 asteroids. Hitherto, spin-axis longitude estimates have been made for fewer than 200 asteroids. We investigate longitude distributions in different dynamical groups and asteroid families. We show that asteroid spin-axis longitudes are not isotropically distributed as previously considered. We find that the spin-axis longitude distribution for main-belt asteroids is clearly non-random, with an excess of longitudes from the interval 30{\\deg}-110{\\deg} and a paucity between 120{\\deg}-180{\\deg}. The explanation of the non-isotropic distribution is unknown at this point. Further studies have to be conducted to determine if the shape of the distribution can be explained by observational bias, selection effects, a real physical process or other mechanism.

  16. Circular Interpolation Algorithms of 5-Axis Simultaneous CNC System

    Institute of Scientific and Technical Information of China (English)

    ZHENG Kuijing; SHANG Bo

    2006-01-01

    Spatial circular arc can be machined conveniently by a 5-axis NC machine tool. Based on the data sampling method, circular interpolation in two-dimensional plane is discussed briefly. The key is to solve the problem of circular center expressed in the workpiece coordinate system by means of the transformation matrix. Circular interpolation in three-dimensional space is analyzed in detail. The method of undetermined coefficient is used to solve the center of the spatial circle and the method of coordinate transformation is used to transform the spatial circle into the XY_plane. Circular arc in three-dimensional space can be machined by the positional 5-axis machining and the conical surface can be machined by the continuous 5-axis machining. The velocity control is presented to avoid the feedrate fluctuation. The interpolation algorithms are tested by a simulation example and the interpolation algorithms are proved feasible. The algorithms are applied to the 5-axis CNC system software.

  17. Clinical science workshop: targeting the gut-liver-brain axis.

    Science.gov (United States)

    Patel, Vishal C; White, Helen; Støy, Sidsel; Bajaj, Jasmohan S; Shawcross, Debbie L

    2016-12-01

    A clinical science workshop was held at the ISHEN meeting in London on Friday 11th September 2014 with the aim of thrashing out how we might translate what we know about the central role of the gut-liver-brain axis into targets which we can use in the treatment of hepatic encephalopathy (HE). This review summarises the integral role that inter-organ ammonia metabolism plays in the pathogenesis of HE with specific discussion of the roles that the small and large intestine, liver, brain, kidney and muscle assume in ammonia and glutamine metabolism. Most recently, the salivary and gut microbiome have been shown to underpin the pathophysiological changes which culminate in HE and patients with advanced cirrhosis present with enteric dysbiosis with small bowel bacterial overgrowth and translocation of bacteria and their products across a leaky gut epithelial barrier. Resident macrophages within the liver are able to sense bacterial degradation products initiating a pro-inflammatory response within the hepatic parenchyma and release of cytokines such as tumour necrosis factor alpha (TNF-α) and interleukin-8 into the systemic circulation. The endotoxemia and systemic inflammatory response that are generated predispose both to the development of infection as well as the manifestation of covert and overt HE. Co-morbidities such as diabetes and insulin resistance, which commonly accompany cirrhosis, may promote slow gut transit, promote bacterial overgrowth and increase glutaminase activity and may need to be acknowledged in HE risk stratification assessments and therapeutic regimens. Therapies are discussed which target ammonia production, utilisation or excretion at an individual organ level, or which reduce systemic inflammation and endotoxemia which are known to exacerbate the cerebral effects of ammonia in HE. The ideal therapeutic strategy would be to use an agent that can reduce hyperammonemia and reduce systemic inflammation or perhaps to adopt a combination of

  18. Maternal control of the Drosophila dorsal-ventral body axis.

    Science.gov (United States)

    Stein, David S; Stevens, Leslie M

    2014-01-01

    The pathway that generates the dorsal-ventral (DV) axis of the Drosophila embryo has been the subject of intense investigation over the previous three decades. The initial asymmetric signal originates during oogenesis by the movement of the oocyte nucleus to an anterior corner of the oocyte, which establishes DV polarity within the follicle through signaling between Gurken, the Drosophila Transforming Growth Factor (TGF)-α homologue secreted from the oocyte, and the Drosophila Epidermal Growth Factor Receptor (EGFR) that is expressed by the follicular epithelium cells that envelop the oocyte. Follicle cells that are not exposed to Gurken follow a ventral fate and express Pipe, a sulfotransferase that enzymatically modifies components of the inner vitelline membrane layer of the eggshell, thereby transferring DV spatial information from the follicle to the egg. These ventrally sulfated eggshell proteins comprise a localized cue that directs the ventrally restricted formation of the active Spätzle ligand within the perivitelline space between the eggshell and the embryonic membrane. Spätzle activates Toll, a transmembrane receptor in the embryonic membrane. Transmission of the Toll signal into the embryo leads to the formation of a ventral-to-dorsal gradient of the transcription factor Dorsal within the nuclei of the syncytial blastoderm stage embryo. Dorsal controls the spatially specific expression of a large constellation of zygotic target genes, the Dorsal gene regulatory network, along the embryonic DV circumference. This article reviews classic studies and integrates them with the details of more recent work that has advanced our understanding of the complex pathway that establishes Drosophila embryo DV polarity. For further resources related to this article, please visit the WIREs website. The authors have declared no conflicts of interest for this article. © 2014 Wiley Periodicals, Inc.

  19. Maternal control of the Drosophila dorsal–ventral body axis

    Science.gov (United States)

    Stein, David S.; Stevens, Leslie M.

    2016-01-01

    The pathway that generates the dorsal–ventral (DV) axis of the Drosophila embryo has been the subject of intense investigation over the previous three decades. The initial asymmetric signal originates during oogenesis by the movement of the oocyte nucleus to an anterior corner of the oocyte, which establishes DV polarity within the follicle through signaling between Gurken, the Drosophila Transforming Growth Factor (TGF)-α homologue secreted from the oocyte, and the Drosophila Epidermal Growth Factor Receptor (EGFR) that is expressed by the follicular epithelium cells that envelop the oocyte. Follicle cells that are not exposed to Gurken follow a ventral fate and express Pipe, a sulfotransferase that enzymatically modifies components of the inner vitelline membrane layer of the eggshell, thereby transferring DV spatial information from the follicle to the egg. These ventrally sulfated eggshell proteins comprise a localized cue that directs the ventrally restricted formation of the active Spätzle ligand within the perivitelline space between the eggshell and the embryonic membrane. Spätzle activates Toll, a transmembrane receptor in the embryonic membrane. Transmission of the Toll signal into the embryo leads to the formation of a ventral-to-dorsal gradient of the transcription factor Dorsal within the nuclei of the syncytial blastoderm stage embryo. Dorsal controls the spatially specific expression of a large constellation of zygotic target genes, the Dorsal gene regulatory network, along the embryonic DV circumference. This article reviews classic studies and integrates them with the details of more recent work that has advanced our understanding of the complex pathway that establishes Drosophila embryo DV polarity. PMID:25124754

  20. Early programming of the IGF-I axis

    DEFF Research Database (Denmark)

    Larnkjær, Anni; Ingstrup, Helga Kristensen; Schack-Nielsen, Lene

    2009-01-01

    -I production. Conversely, studies suggest that later in childhood, those breastfed are taller and have higher IGF-I levels. Therefore, it has been suggested that the IGF-I axis may be programmed by diet during infancy. The association between IGF-I in infancy and later life is not known. OBJECTIVE: To examine......=-0.26, P=0.043, and n=109). CONCLUSION: The results support the hypothesis that the IGF-I axis can be programmed early in life....

  1. Performance Characterization of a Three-Axis Hall Effect Thruster

    Science.gov (United States)

    2010-12-01

    here represents the first efforts to operate and quantify the performance of a three-axis Hall effect thruster. This thruster is based on the Busek BHT ...thruster were developed and thrust and current density measurements were performed and compared with the baseline BHT -200. The three-axis thruster was...efficiencies than the BHT -200. Beam current density measurements conducted using a guarded Faraday probe showed significant differences in plume divergence

  2. Traumatic Spondylolisthesis of the Axis Vertebra in Adults

    OpenAIRE

    Schleicher, Philipp; Scholz, Matti; Pingel, Andreas; Kandziora, Frank

    2015-01-01

    Study Design Narrative review. Objective To elucidate the current concepts in diagnosis and treatment of traumatic spondylolisthesis of the axis. Methods Literature review using PubMed, Google Scholar, and Cochrane databases. Results The traumatic spondylolisthesis of the axis accounts to 5% of all cervical spine injuries and is defined by a bilateral separation of the C2 vertebral body from the neural arch. The precise location of the fracture line may vary widely. For understanding the path...

  3. Improved Controller for a Three-Axis Piezoelectric Stage

    Science.gov (United States)

    Rao, Shanti; Palmer, Dean

    2009-01-01

    An improved closed-loop controller has been built for a three-axis piezoelectric positioning stage. The stage can be any of a number of commercially available or custom-made units that are used for precise three-axis positioning of optics in astronomical instruments and could be used for precise positioning in diverse fields of endeavor that include adaptive optics, fabrication of semiconductors, and nanotechnology.

  4. The reno-pineal axis: A novel role for melatonin

    Directory of Open Access Journals (Sweden)

    Sanjay Kalra

    2012-01-01

    Full Text Available The pineal gland is a tiny endocrine gland whose physiologic role has been the focus of much research and much more speculation over the past century. This mini-review discusses recent findings which correlate melatonin and renal physiology, and postulates the presence of a "reno-pineal axis." Drawing lessons from comparative endocrinology, while quoting human data, it advocates the need to study the "reno-pineal axis" in greater detail.

  5. DARHT Axis-I Diode Simulations II: Geometric Scaling

    OpenAIRE

    Ekdahl, Carl

    2017-01-01

    The dual-axis radiography for hydrodynamic testing (DARHT) facility at Los Alamos National Laboratory uses two electron linear-induction accelerators (LIA) to produce the source spots for perpendicular flash radiographs of a dynamic experiment.Manipulating the beam current is a means for adjusting the dose, and one way to do this is to change the size of the cathode. This article describes simulations undertaken to develop scaling laws for use as design tools in changing the Axis-1 beam curre...

  6. Application of Circulation Controlled Blades for Vertical Axis Wind Turbines

    OpenAIRE

    Shires, A.; Kourkoulis, V

    2013-01-01

    The blades of a vertical axis wind turbine (VAWT) rotor see an inconsistent angle of attack through its rotation. Consequently, VAWT blades generally use symmetrical aerofoils with a lower lift-to-drag ratio than cambered aerofoils tailored to maximise horizontal axis wind turbine rotor performance. This paper considers the feasibility of circulation controlled (CC) VAWT blades, using a tangential air jet to provide lift and therefore power augmentation. However CC blade sections require a hi...

  7. Sensitivity Analysis of the Transmission Chain of a Horizontal Machining Tool Axis to Design and Control Parameters

    Directory of Open Access Journals (Sweden)

    Stefano Mauro

    2014-03-01

    Full Text Available This paper reports how a numerical controlled machine axis was studied through a lumped parameter model. Firstly, a linear model was derived in order to apply a modal analysis, which estimated the first mechanical frequency of the system as well as its damping coefficients. Subsequently, a nonlinear system was developed by adding friction through experimentation. Results were validated through the comparison with a commercial servoaxis equipped with a Siemens controller. The model was then used to evaluate the effect of the stiffness of the structural parts of the axis on its first natural frequency. It was further used to analyse precision, energy consumption, and axis promptness. Finally a cost function was generated in order to find an optimal value for the main proportional gain of the position loop.

  8. Nanometer-level axis of rotation metrology for a high-precision macromolecular X-ray diffractometer

    Science.gov (United States)

    Knapp, B.; Marsh, E.; Cipriani, F.; Arneson, D.; Oss, D.; Liebers, M.; Keller, E.

    2013-03-01

    The availability of micro-focused beams at 3rd generation synchrotrons makes collecting X-ray data from macromolecular crystals down to a fraction of micron size possible. This requires using goniometers with nanometer-level errors. Crystal positioning is typically realized with a multi-axis goniometer designed to minimize error motion during rotation of the crystal by the data-collection axis. In this paper, five degree-of-freedom error motions of an air bearing diffractometer data-collection axis are evaluated using a multiprobe method. As spindle errors and artifact out-of-roundness approach equal magnitudes, techniques must be used to distinguish and separate each error. A purpose-built fixture orients a single capacitive sensor in three asymmetrical positions to separate artifact form error from spindle error motion. Metrology results of this air bearing Omega spindle demonstrate synchronous errors of 16 nm radial, 4 nm axial and 0.28 μrad tilt.

  9. Optic axis-driven new horizons for hyperbolic metamaterials

    Directory of Open Access Journals (Sweden)

    Boardman Allan D.

    2015-01-01

    Full Text Available The broad assertion here is that the current hyperbolic metamaterial world is only partially served by investigations that incorporate only some limited version of anisotropy. Even modest deviations of the optic axis from the main propagation axis lead to new phase shifts, which not only compete with those created by absorption but end up dominating them. Some progress has been attempted in the literature by introducing the terms “asymmetric hyperbolic media”, but it appears that this kind of asymmetry only involves an optic axis at an angle to the interface of a uniaxial crystal. From a device point of view, many new prospects should appear and the outcomes of the investigations presented here yield a new general theory. It is emphasised that the orientation of the optic axis is a significant determinant in the resulting optical properties. Whereas for conventional anisotropic waveguides homogeneous propagating waves occur over a limited range of angular dispositions of the optic axis it is shown that for a hyperbolic guide a critical angular setting exists, above which the guided waves are always homogeneous. This has significant implications for metawaveguide designs. The resulting structures are more tolerant to optic axis misalignment.

  10. Off-Axis Aspheric Surfacing Using Sub-Aperture Tools

    Science.gov (United States)

    Feng, Yunpeng; Qiao, Xiaoyan; Cheng, Haobo; Tam, Hon-Yuen

    2013-10-01

    The off-axis aspheric surface used in modern optical systems widely can obtain nearly perfect quality, realize both small packet-size and low-mass, and avoid the central obscuration. But it is difficult to fabricate because of asymmetry. There are some key technologies during the testing and fabrication of off-axis asphere. In this article, we proposed a method of the best fit sphere based on non-negative minimized removal criterion. And a measured data fitting algorithm was presented to estimate the geometry parameters of off-axis aspheric surface. Then an off-axis mirror was fabricated, and the interferometrically measured data was corrected to eliminate the distortion introduced by null compensator in every run. Finally, the surface error of off-axis mirror reduced to pv = 0.372λ, rms = 0.046λ, the surface roughness reached 0.72 nm. These methods mentioned in the article are suitable for off-axis aspheric optics.

  11. Energy Efficient Hybrid Dual Axis Solar Tracking System

    Directory of Open Access Journals (Sweden)

    Rashid Ahammed Ferdaus

    2014-01-01

    Full Text Available This paper describes the design and implementation of an energy efficient solar tracking system from a normal mechanical single axis to a hybrid dual axis. For optimizing the solar tracking mechanism electromechanical systems were evolved through implementation of different evolutional algorithms and methodologies. To present the tracker, a hybrid dual-axis solar tracking system is designed, built, and tested based on both the solar map and light sensor based continuous tracking mechanism. These light sensors also compare the darkness and cloudy and sunny conditions assisting daily tracking. The designed tracker can track sun’s apparent position at different months and seasons; thereby the electrical controlling device requires a real time clock device for guiding the tracking system in seeking solar position for the seasonal motion. So the combination of both of these tracking mechanisms made the designed tracker a hybrid one. The power gain and system power consumption are compared with a static and continuous dual axis solar tracking system. It is found that power gain of hybrid dual axis solar tracking system is almost equal to continuous dual axis solar tracking system, whereas the power saved in system operation by the hybrid tracker is 44.44% compared to the continuous tracking system.

  12. Generating Units

    Data.gov (United States)

    Department of Homeland Security — Generating Units are any combination of physically connected generators, reactors, boilers, combustion turbines, and other prime movers operated together to produce...

  13. Large-charge quasimonoenergetic electron beams produced by off-axis colliding laser pulses in underdense plasma

    Science.gov (United States)

    Deng, Z. G.; Zhang, Z. M.; Zhang, B.; He, S. K.; Teng, J.; Hong, W.; Dong, K. G.; Wu, Y. C.; Zhu, B.; Gu, Y. Q.

    2017-02-01

    Electrons can be efficiently injected into a plasma wave by colliding two counterpropagating laser pulses in a laser wakefield acceleration. However, the generation of a high-quality electron beam with a large charge is difficult in the traditional on-axis colliding scheme due to the growth of the electron beam duration coming from the increase of the beam charge. To solve this problem, we propose an off-axis colliding scheme, in which the collision point is away from the axis of the driver pulse. We show that the electrons injected from the off-axis region are highly concentered on the tail of the bubble even for a large trapped charge, thus feeling almost the same accelerating field. As a result, quasimonoenergetic electron beams with a large charge can be produced. The validity of this scheme is confirmed by both the particle-in-cell simulations and the Hamiltonian model. Furthermore, it is shown that a Laguerre-Gauss (LG) laser can be adopted as the injection pulse to realize the off-axis colliding injection in three dimensions symmetrically, which may be useful in simplifying the technical layout of the real experiment setup.

  14. Multi-axis control based on movement control cards in NC systems

    Science.gov (United States)

    Jiang, Tingbiao; Wei, Yunquan

    2005-12-01

    Today most movement control cards need special control software of topper computers and are only suitable for fixed-axis controls. Consequently, the number of axes which can be controlled is limited. Advanced manufacture technology develops at a very high speed, and that development brings forth. New requirements for movement control in mechanisms and electronics. This paper introduces products of the 5th generation of movement control cards, PMAC 2A-PC/104, made by the Delta Tau Company in the USA. Based on an analysis of PMAC 2A-PC/104, this paper first describes two aspects relevant to the hardware structure of movement control cards and the interrelated software of the topper computers. Then, two methods are presented for solving these problems. The first method is to set limit switches on the movement control cards; all of them can be used to control each moving axis. The second method is to program applied software with existing programming language (for example, VC ++, Visual Basic, Delphi, and so forth). This program is much easier to operate and expand by its users. By using a limit switch, users can choose different axes in movement control cards. Also, users can change parts of the parameters in the control software of topper computers to realize different control axes. Combining these 2 methods proves to be convenient for realizing multi-axis control in numerical control systems.

  15. Simulation study on the emittance compensation of off-axis emitted beam in RF photoinjector

    Science.gov (United States)

    Huang, Rui-Xuan; Mitchell, Chad; Jia, Qi-Ka; Papadopoulos, Christos; Sannibale, Fernando

    2016-11-01

    To make full use of the photocathode material and improve its quantum efficiency lifetime, it can be necessary to operate the laser away from the cathode center in photoinjectors. In RF guns, the off-axis emitted beam will see a time-dependent RF effect, which would generate a significant growth in transverse emittance. It has been demonstrated that such an emittance growth can be almost completely compensated by orienting the beam on a proper orbit in the downstream RF cavities along the injector [1]. In this paper we analyze in detail the simulation techniques used in reference [1] and the issues associated with them. The optimization of photoinjector systems involving off-axis beams is a challenging problem. To solve this problem, one needs advanced simulation tools including both genetic algorithms and an efficient algorithm for 3D space charge. In this paper, we report on simulation studies where the two codes ASTRA and IMPACT-T are used jointly to overcome these challenges, in order to optimize a system designed to compensate for the emittance growth in a beam emitted off axis. Supported by National Nature Science Foundation of China (11375199), and Chinese Scholarship Council

  16. A TWO-DOF Controlled Lens Drive Actuator for Off-Axis Laser Beam Cutting

    Science.gov (United States)

    Morimoto, Yoshihiro; Shinshi, Tadahiko; Nakai, Takahiro

    This paper describes a two-degree-of-freedom (two-DOF) controlled electromagnetic actuator guided by an elastic hinge mechanism to realize off-axis laser beam cutting. In the laser beam cutting process, a focused laser beam melts and vaporizes part of the workpiece, and the molten material is blown away by an assist gas jet. The cutting speed and quality are related to the flow of the assist gas jet. In order to improve the removal capability of the molten material and to reduce gas consumption in off-axis laser beam cutting, the lens is driven radially by the proposed two-DOF actuator to generate relative motion between the assist gas nozzle and the laser. Experimental results show the prototype actuator possesses a positioning stroke of ±500µm within 3µm of tracking error and bandwidths more than 150Hz in the two-DOF directions. In the acceleration test supposed at a maximum acceleration of 2G, the prototype actuator maintains the relative displacement between the lens holder and the laser head within 10µm. Off-axis laser beam cutting by using the prototype actuator achieves high speed and less dross processing.

  17. An empirical method for calculating melt compositions produced beneath mid-ocean ridges: Application for axis and off-axis (seamounts) melting

    Science.gov (United States)

    Niu, Yaoling; Batiza, Rodey

    1991-12-01

    We present a new method for calculating the major element compositions of primary melts parental to mid-ocean ridge basalt (MORB). This model is based on the experimental data of Jaques and Green (1980), Falloon et al. (1988), and Falloon and Green (1987, 1988) which are ideal for this purpose. Our method is empirical and employs solid-liquid partition coefficients (Di) from the experiments. We empirically determine Di = ƒ(P,F) and use this to calculate melt compositions produced by decompression-induced melting along an adiabat (column melting). Results indicate that most MORBs can be generated by 10-20% partial melting at initial pressures (P0) of 12-21 kbar. Our primary MORB melts have MgO = 10-12 wt %. We fractionate these at low pressure to an MgO content of 8.0 wt % in order to interpret natural MORB liquids. This model allows us to calculate Po, Pƒ, To, Tƒ, and F for natural MORB melts. We apply the model to interpret MORB compositions and mantle upwelling patterns beneath a fast ridge (East Pacific Rise (EPR)8°N to 14°N), a slow ridge (mid-Atlantic Ridge (MAR) at 26°S), and seamounts near the EPR (Lament seamount chain). We find mantle temperature differences of up to 50°-60°C over distances of 30-50 km both across axis and along axis at the EPR. We propose that these are due to upward mantle flow in a weakly conductive (versus adiabatic) temperature gradient. We suggest that the EPR is fed by a wide (-100 km) zone of upwelling due to plate separation but has a central core of faster buoyant flow. An along-axis thermal dome between the Siqueiros transform and the 11°45' Overlapping Spreading center (OSC) may represent such an upwelling; however, in general there is a poor correlation between mantle temperature, topography, and the segmentation pattern at the EPR. For the Lament seamounts we find regular across-axis changes in Po and F suggesting that the melt zone pinches out off axis. This observation supports the idea that the EPR is fed by a

  18. An empirical method for calculating melt compositions produced beneath mid-ocean ridges: for axis and off-axis (seamounts) melting application

    Science.gov (United States)

    Batiza, Rodey

    1991-12-01

    We present a new method for calculating the major element compositions of primary melts parental to mid-ocean ridge basalt (MORB). This model is based on the experimental data of Jaques and Green (1980), Falloon et al. (1988), and Falloon and Green (1987, 1988) which are ideal for this purpose. Our method is empirical and employs solid-liquid partition coefficients (Di) from the experiments. We empirically determine Di=f(P,F) and use this to calculate melt compositions produced by decompression-induced melting along an adiabat (column melting). Results indicate that most MORBs can be generated by 10-20% partial melting at initial pressures (P0) of 12-21 kbar. Our primary MORB melts have MgO=10-12 wt %. We fractionate these at low pressure to an MgO content of 8.0 wt% in order to interpret natural MORB liquids. This model allows us to calculate Po, Pf, To, Tf, and F for natural MORB melts. We apply the model to interpret MORB compositions and mantle upwelling patterns beneath a fast ridge (East Pacific Rise (EPR) 8°N to 14°N), a slow ridge (mid-Atlantic Ridge (MAR) at 26°S), and seamounts near the EPR (Lamont seamount chain). We find mantle temperature differences of up to 50°-60°C over distances of 30-50 km both across axis and along axis at the EPR. We propose that these are due to upward mantle flow in a weakly conductive (versus adiabatic) temperature gradient. We suggest that the EPR is fed by a wide (~100 km) zone of upwelling due to plate separation but has a central core of faster buoyant flow. An along-axis thermal dome between the Siqueiros transform and the 11°45' Overlapping Spreading Center (OSC) may represent such an upwelling; however, in general there is a poor correlation between mantle temperature, topography, and the segmentation pattern at the EPR. For the Lamont seamounts we find regular across-axis changes in Po and F suggesting that the melt zone pinches out off axis. This observation supports the idea that the EPR is fed by a broad

  19. Design of multi-energy Helds coupling testing system of vertical axis wind power system

    Science.gov (United States)

    Chen, Q.; Yang, Z. X.; Li, G. S.; Song, L.; Ma, C.

    2016-08-01

    The conversion efficiency of wind energy is the focus of researches and concerns as one of the renewable energy. The present methods of enhancing the conversion efficiency are mostly improving the wind rotor structure, optimizing the generator parameters and energy storage controller and so on. Because the conversion process involves in energy conversion of multi-energy fields such as wind energy, mechanical energy and electrical energy, the coupling effect between them will influence the overall conversion efficiency. In this paper, using system integration analysis technology, a testing system based on multi-energy field coupling (MEFC) of vertical axis wind power system is proposed. When the maximum efficiency of wind rotor is satisfied, it can match to the generator function parameters according to the output performance of wind rotor. The voltage controller can transform the unstable electric power to the battery on the basis of optimizing the parameters such as charging times, charging voltage. Through the communication connection and regulation of the upper computer system (UCS), it can make the coupling parameters configure to an optimal state, and it improves the overall conversion efficiency. This method can test the whole wind turbine (WT) performance systematically and evaluate the design parameters effectively. It not only provides a testing method for system structure design and parameter optimization of wind rotor, generator and voltage controller, but also provides a new testing method for the whole performance optimization of vertical axis wind energy conversion system (WECS).

  20. Ultrasound-guided internal jugular vein access: Comparison between short axis and long axis techniques

    Directory of Open Access Journals (Sweden)

    Tarek F Tammam

    2013-01-01

    Full Text Available The use of real-time ultrasound (US is advantageous in the insertion of central venous catheters (CVCs in adults, especially in whom difficulties are anticipated for various reasons. The aim of the present study was to compare two different real-time 2-dimensional US-guided techniques [short axis view/out-of-plane approach (SAX OOP approach versus long axis view/in-plane approach (LAX IP approach] for internal jugular vein (IJV cannulation. In this prospective study, 90 critical care and hemodialysis patients were assigned for insertion of CVCs using either the real-time US-guided (SAX OOP approach or LAX IP approach or landmark technique (control group. Failed catheter placement, risk of complications from placement, failure on first attempt at placement, number of attempts until successful catheterization, time to successful catheterization, incidence of central line-associated blood stream infection (CLA-BSI and demographics of each patient were recorded. There were no significant differences in patient′s demographic characteristics, side of cannulation (right or left or presence of risk factors for difficult venous cannulation between the three groups of patients. Cannulation of the IJV was achieved in all patients by using US (SAX OOP and LAX IP approaches and in 27 of the patients (90% by using the landmark technique (P = 0.045. Average access time (skin to vein and number of attempts were comparable between the SAX OOP and the LAX IP approaches while significantly reduced in both US groups of patients compared with the landmark group (P <0.001. In the landmark group, puncture of the carotid artery occurred in 16.7% of the patients, hematoma in 23.3% of the patients, pneumothorax in 3.3% of the patients and CLA-BSI in 20% of the patients, which were all significantly increased compared with the US group (P <0.05. The findings of this study suggest that the SAX OOP and LAX IP approaches were comparable for cannulation of IJV in critical

  1. Generational diversity.

    Science.gov (United States)

    Kramer, Linda W

    2010-01-01

    Generational diversity has proven challenges for nurse leaders, and generational values may influence ideas about work and career planning. This article discusses generational gaps, influencing factors and support, and the various generational groups present in today's workplace as well as the consequences of need addressing these issues. The article ends with a discussion of possible solutions.

  2. CRYOPAD on the triple-axis spectrometer TAS-1 at JAERI

    Energy Technology Data Exchange (ETDEWEB)

    Takeda, Masayasu [Advanced Science Research Center, Japan Atomic Energy Research Institute, 2-4 Shirakata Shirane, Tokai, Naka, Ibaraki 319-1195 (Japan)]. E-mail: takeda@neutrons.tokai.jaeri.go.jp; Nakamura, Mitsutaka [Advanced Science Research Center, Japan Atomic Energy Research Institute, 2-4 Shirakata Shirane, Tokai, Naka, Ibaraki 319-1195 (Japan); Kakurai, Kazuhisa [Advanced Science Research Center, Japan Atomic Energy Research Institute, 2-4 Shirakata Shirane, Tokai, Naka, Ibaraki 319-1195 (Japan); Lelievre-berna, Eddy [Institut Laue-Langevin, 6 rue Jules Horowitz BP 156 - 38042 Grenoble Cedex 9 (France); Tasset, Francis [Institut Laue-Langevin, 6 rue Jules Horowitz BP 156 - 38042 Grenoble Cedex 9 (France); Regnault, Louis-Pierre [CEA-Grenoble, Department de Recherche Fondamentale sur la Matiere Condensee, SPSMS-MDN, F-38054 Grenoble Cedex 9 (France)

    2005-02-15

    CRYOgenic Polarization Analysis Device (CRYOPAD) has been introduced to the triple-axis spectrometer TAS-1 at JRR-3 in JAERI. ILL, CEA-Grenoble and JAERI assembled three third-generation CRYOPADs in the framework of EC/ENPI (ILL and CEA-Grenoble), and in the framework of the MoU between ILL and JAERI. One is installed on the ILL instrument D3 (Millennium Project) and the other on the CEA-Grenoble instrument IN22. The JAERI CRYOPAD is now in commissioning. The current status of the CRYOPAD on TAS-1 is reported.

  3. Numerical investigation of vibration and dynamic pressure of a vertical axis wind turbine

    Directory of Open Access Journals (Sweden)

    F Erchiqui

    2016-10-01

    Full Text Available In the environmental field, the problems of noise reduction have become a major preoccupation, particularly on the noise generated by the acoustic radiation pressure produced by wind turbines. This paper is aimed at presenting the investigation on the application of variational indirect boundary element method for study the acoustic radiation pressure produced by vertical-axis wind turbine. For this initiative, we considered Neumann boundary condition. The formulation has two advantages: the first one is to avoid the meshing of the fluid domain; the second advantage is to treat the singular integral of the Green's function, solution of fundamental solution of the wave equation in frequency domain.

  4. Diagnostic X-Multi-Axis Beamline

    Energy Technology Data Exchange (ETDEWEB)

    Paul, A C

    2000-04-05

    Tomographic reconstruction of explosive events require time resolved multipal lines of sight. Considered here is a four (or eight) line of sight beam layout for a nominal 20 MeV 2000 Ampere 2 microsecond electron beam for generation of x-rays 0.9 to 5 meters from a given point, the ''firing point''. The requirement of a millimeter spatial x-ray source requires that the electron beam be delivered to the converter targets with sub-millimeter precision independent of small variations in beam energy and initial conditions. The 2 usec electron beam pulse allows for four bursts in each line, separated in time by about 500 microseconds. Each burst is divided by a electro-magnetic kicker into four (or eight) pulses, one for each beamline. The arrival time of the four (or eight) beam pulses at the x-ray target can be adjusted by the kicker timing and the sequence that the beams of each burst are switched into the different beamlines. There exists a simple conceptual path from a four beamline to a eight beamline upgrade. The eight line beamline is built up from seven unique types of sub-systems or ''blocks''. The beamline consists of 22 of these functional blocks and contains a total of 455 individual magnets, figure 1. The 22 blocks are inter-connected by a total of 30 straight line inter-block sections (IBS). Beamlines 1-4 are built from 12 blocks with conceptual layout structure shown in figure 2. Beamlines 5-8 are built with an additional 10 blocks with conceptual layout structure shown in figure 3. This beamline can be thought of as looking like a lollipop consisting of a 42 meter long stick leading to a 60 by 70 meter rectangular candy blob consisting of the eight lines of sight. The accelerator providing the electron beam is at the end of the stick and the firing point is at the center of the blob. The design allows for a two stage implementation. Beamlines 1-3 can be installed to provide a tomographic azimuthal resolution of 45

  5. Simulation study of MEMS piezoelectric vibration energy harvester based on c-axis tilted AlN thin film for performance improvement

    Directory of Open Access Journals (Sweden)

    Lingfeng Kong

    2016-12-01

    Full Text Available In this paper, a MEMS piezoelectric cantilevered vibration energy harvester based on c-axis tilted AlN thin film is investigated. Based on basic piezoelectric equations and static analysis of cantilever beam, the equations for generated energy (E and open circuit voltage (Vo were derived, and simulations were carried out to study the effects of geometry parameters and c-axis tilted angle. Results show that E and Vo of energy harvesters are greatly dependent on c-axis tilted angle and geometry parameters, while the coupling between c-axis tilted angle and geometry parameters is not strong. For a given structure size, E and Vo can be almost simultaneously improved by controlling c-axis tilted angle; compared with the case of normal c-axis angle, E with optimal c-axis tilted angle can be amplified by more than 3 times, and the Vo is amplified by about 2 times. E or Vo could be further improved by geometry parameters, while there is trade-off between them. These results can be used for the design and application of piezoelectric cantilevered vibration energy harvester.

  6. Alignment method of off-axis RC reflective optical system

    Science.gov (United States)

    Xue-min, Zhang; Xing, Song; Zhi-jun, Zhang; Hou, Xiao-hua

    2016-10-01

    Off-axis optical system has a wide application in space optics and remote detective area. The high surface shape accuracy can be ensured with the development of advanced manufacture technique. So the only condition which limits the wide application of off-axis optical system is how to realize the precise alignment of it. Based on a RC reflective optical system whose diameter is 400mm, the alignment method which combines the high resolution initial placement and computer-aided alignment is introduced. By designing a system which can measure the off-axis fabrication and off-axis angle precisely, the high resolution initial placement of off-axis mirror can be ensured with a measurement accuracy of +/-0.05mm and +/-10". The good initial placement can give a good initial state, so the computer-aided model can be converged well. The experiment shows that a system which has a good initial placement could have a good wave aberration of 0.04λ after three times iteration adjustment.

  7. Mifepristone Accelerates HPA Axis Recovery in Secondary Adrenal Insufficiency.

    Science.gov (United States)

    Cohan, Pejman

    2016-01-01

    Context. Transient secondary adrenal insufficiency (SAI) is an expected complication following successful adenomectomy of ACTH-secreting pituitary adenomas or unilateral adrenalectomy for cortisol-secreting adrenal adenomas. To date, no pharmacological therapy has been shown to hasten recovery of the hypothalamic-pituitary-adrenal (HPA) axis in this clinical scenario. Case Description. A 33-year-old woman underwent uncomplicated unilateral adrenalectomy for a 3.7 cm cortisol-secreting adrenal adenoma. Postoperatively, she developed SAI and was placed on hydrocortisone 15 mg/day, given in divided doses. In the ensuing six years, the patient's HPA axis failed to recover and she remained corticosteroid-dependent. Quarterly biochemical testing (after withholding hydrocortisone for 18 hours) consistently yielded undetectable serum cortisol and subnormal plasma ACTH levels. While she was on hydrocortisone 15 mg/day, mifepristone was initiated and gradually titrated to a maintenance dose of 600 mg/day after 5 months. Rapid recovery of the HPA axis was subsequently noted with ACTH rising into the supranormal range at 4 months followed by a subsequent rise in cortisol levels into the normal range. After 6 months, the dose of hydrocortisone and mifepristone was lowered and both were ultimately stopped after 8 months. The HPA axis remains normal after an additional 16 months of follow-up. Conclusion. Mifepristone successfully restored the HPA axis in a woman with prolonged secondary adrenal insufficiency (SAI) after adrenalectomy for Cushing's syndrome (CS).

  8. An FGF3-BMP Signaling Axis Regulates Caudal Neural Tube Closure, Neural Crest Specification and Anterior-Posterior Axis Extension.

    Directory of Open Access Journals (Sweden)

    Matthew J Anderson

    2016-05-01

    Full Text Available During vertebrate axis extension, adjacent tissue layers undergo profound morphological changes: within the neuroepithelium, neural tube closure and neural crest formation are occurring, while within the paraxial mesoderm somites are segmenting from the presomitic mesoderm (PSM. Little is known about the signals between these tissues that regulate their coordinated morphogenesis. Here, we analyze the posterior axis truncation of mouse Fgf3 null homozygotes and demonstrate that the earliest role of PSM-derived FGF3 is to regulate BMP signals in the adjacent neuroepithelium. FGF3 loss causes elevated BMP signals leading to increased neuroepithelium proliferation, delay in neural tube closure and premature neural crest specification. We demonstrate that elevated BMP4 depletes PSM progenitors in vitro, phenocopying the Fgf3 mutant, suggesting that excessive BMP signals cause the Fgf3 axis defect. To test this in vivo we increased BMP signaling in Fgf3 mutants by removing one copy of Noggin, which encodes a BMP antagonist. In such mutants, all parameters of the Fgf3 phenotype were exacerbated: neural tube closure delay, premature neural crest specification, and premature axis termination. Conversely, genetically decreasing BMP signaling in Fgf3 mutants, via loss of BMP receptor activity, alleviates morphological defects. Aberrant apoptosis is observed in the Fgf3 mutant tailbud. However, we demonstrate that cell death does not cause the Fgf3 phenotype: blocking apoptosis via deletion of pro-apoptotic genes surprisingly increases all Fgf3 defects including causing spina bifida. We demonstrate that this counterintuitive consequence of blocking apoptosis is caused by the increased survival of BMP-producing cells in the neuroepithelium. Thus, we show that FGF3 in the caudal vertebrate embryo regulates BMP signaling in the neuroepithelium, which in turn regulates neural tube closure, neural crest specification and axis termination. Uncovering this FGF3

  9. An FGF3-BMP Signaling Axis Regulates Caudal Neural Tube Closure, Neural Crest Specification and Anterior-Posterior Axis Extension.

    Science.gov (United States)

    Anderson, Matthew J; Schimmang, Thomas; Lewandoski, Mark

    2016-05-01

    During vertebrate axis extension, adjacent tissue layers undergo profound morphological changes: within the neuroepithelium, neural tube closure and neural crest formation are occurring, while within the paraxial mesoderm somites are segmenting from the presomitic mesoderm (PSM). Little is known about the signals between these tissues that regulate their coordinated morphogenesis. Here, we analyze the posterior axis truncation of mouse Fgf3 null homozygotes and demonstrate that the earliest role of PSM-derived FGF3 is to regulate BMP signals in the adjacent neuroepithelium. FGF3 loss causes elevated BMP signals leading to increased neuroepithelium proliferation, delay in neural tube closure and premature neural crest specification. We demonstrate that elevated BMP4 depletes PSM progenitors in vitro, phenocopying the Fgf3 mutant, suggesting that excessive BMP signals cause the Fgf3 axis defect. To test this in vivo we increased BMP signaling in Fgf3 mutants by removing one copy of Noggin, which encodes a BMP antagonist. In such mutants, all parameters of the Fgf3 phenotype were exacerbated: neural tube closure delay, premature neural crest specification, and premature axis termination. Conversely, genetically decreasing BMP signaling in Fgf3 mutants, via loss of BMP receptor activity, alleviates morphological defects. Aberrant apoptosis is observed in the Fgf3 mutant tailbud. However, we demonstrate that cell death does not cause the Fgf3 phenotype: blocking apoptosis via deletion of pro-apoptotic genes surprisingly increases all Fgf3 defects including causing spina bifida. We demonstrate that this counterintuitive consequence of blocking apoptosis is caused by the increased survival of BMP-producing cells in the neuroepithelium. Thus, we show that FGF3 in the caudal vertebrate embryo regulates BMP signaling in the neuroepithelium, which in turn regulates neural tube closure, neural crest specification and axis termination. Uncovering this FGF3-BMP signaling axis is

  10. A Simplified Approach To The Control System On A 4-Axis Curve Generator

    Science.gov (United States)

    Langdon, Wayne R.

    1989-12-01

    The simplest approach in developing a Computerized Numerical Control (CNC) machine tool would be to take a manually-operated machine and fit it with a standard, commercially available computer control system and drive packages, or so it would appear from a machine designer's viewpoint. This approach does tend to minimize the overall machine/system development costs; however, it can result in a control system too sophisticated, overly complex, and more expensive than necessary to control the machine.

  11. [Economic development axis and socioenvironmental conflicts generation in Brazil: challenges to sustainability and environmental justice].

    Science.gov (United States)

    Porto, Marcelo Firpo; Milanez, Bruno

    2009-01-01

    The 1st National Environmental Health Conference, in December 2009, presents countless challenges to the field of Public Health. It debates key concepts as development, sustainability, production and consumption processes, democracy and public policies; advocating for innovative, interdisciplinary and intersectorial aspects of Environmental Health. The Conference recovers and articulates important themes for the Public Health, and also indicates the need of reflecting the socio-environmental determinants of health at the present time, in order to provide progresses in the construction of guidelines and actions to health surveillance and promotion. This article discusses the characteristics of the Brazilian model of development, its impacts and conflicts within social, environmental and health fields. We use theoretical and empirical contributions from the fields of Ecological Economy and Political Ecology, as well as, experiences of cooperation with the Brazilian Network on Environmental Justice and several social movements. Two cases are discussed in more detail: the first related to agribusiness and the use of pesticides, and the other about the expansion of the iron and steel industry in Brazil. We conclude proposing some elements that could be incorporated by a research agenda committed to the debate about the 'socioenvironmental crisis'.

  12. Chronic Lyme disease and the 'Axis of Evil'.

    Science.gov (United States)

    Stricker, Raphael B; Johnson, Lorraine

    2008-12-01

    Lyme disease is a controversial illness, and the existence of chronic Lyme disease induced by persistent infection with the Lyme spirochete, Borrelia burgdorferi, is the subject of continued debate. A recent publication defined the 'Axis of Evil' in this controversy as physicians who treat patients with needlessly prolonged courses of antibiotics, 'specialty laboratories' that perform 'inaccurate' Lyme testing and the internet, which promotes 'Lyme hysteria'. We examine the 'Axis of Evil' components in the context of diagnostic and therapeutic challenges for Lyme disease patients and their physicians, and we present an evidence-based refutation to this misguided view. Despite its virulent nature, the 'Axis of Evil' perspective is a useful starting point to resolve the controversy over Lyme disease.

  13. Dual axis operation of a micromachined rate gyroscope

    Energy Technology Data Exchange (ETDEWEB)

    Juneau, T. [BSAC, Berkeley, CA (United States); Pisano, A.P. [Univ. California, Berkeley, CA (United States). Dept. of Mechanical Engineering; Smith, J. [Sandia National Lab., Albuquerque, NM (United States)

    1997-04-01

    Since micromachining technology has raised the prospect of fabricating high performance sensors without the associated high cost and large size, many researchers have investigated micromachined rate gyroscopes. The vast majority of research has focused on single input axis rate gyroscopes, but this paper presents work on a dual input axis micromachined rate gyroscope. The key to successful simultaneous dual axis operation is the quad symmetry of the circular oscillating rotor design. Untuned gyroscopes with mismatched modes yielded random walk as low as 10{degrees}/{radical}hour with cross sensitivity ranging from 6% to 16%. Mode frequency matching via electrostatic tuning allowed performance better than 2{degrees}/{radical}hour, but at the expense of excessive cross sensitivity.

  14. The microbiota-gut-brain axis in functional gastrointestinal disorders

    Science.gov (United States)

    De Palma, Giada; Collins, Stephen M; Bercik, Premysl

    2014-01-01

    Functional gastrointestinal disorders (FGIDs) are highly prevalent and pose a significant burden on health care and society, and impact patients’ quality of life. FGIDs comprise a heterogeneous group of disorders, with unclear underlying pathophysiology. They are considered to result from the interaction of altered gut physiology and psychological factors via the gut-brain axis, where brain and gut symptoms are reciprocally influencing each other’s expression. Intestinal microbiota, as a part of the gut-brain axis, plays a central role in FGIDs. Patients with Irritable Bowel Syndrome, a prototype of FGIDs, display altered composition of the gut microbiota compared with healthy controls and benefit, at the gastrointestinal and psychological levels, from the use of probiotics and antibiotics. This review aims to recapitulate the available literature on FGIDs and microbiota-gut-brain axis. PMID:24921926

  15. Helly-type Theorems for Hollow Axis-aligned Boxes

    CERN Document Server

    Swanepoel, Konrad J

    2009-01-01

    A hollow axis-aligned box is the boundary of the cartesian product of $d$ compact intervals in R^d. We show that for d\\geq 3, if any 2^d of a collection of hollow axis-aligned boxes have non-empty intersection, then the whole collection has non-empty intersection; and if any 5 of a collection of hollow axis-aligned rectangles in R^2 have non-empty intersection, then the whole collection has non-empty intersection. The values 2^d for d\\geq 3 and 5 for d=2 are the best possible in general. We also characterize the collections of hollow boxes which would be counterexamples if 2^d were lowered to 2^d-1, and 5 to 4, respectively.

  16. Chandra X-ray Observatory Optical Axis and Aimpoint

    Science.gov (United States)

    Zhao, Ping

    2016-01-01

    Chandra X-ray Observatory revolutionized the X-ray astronomy as being the first, and so far the only, X-ray telescope achieving sub-arcsecond resolution. Chandra comprises of three principal elements: the High Resolution Mirror Assembly (HRMA), Pointing Control and Aspect Determination (PCAD) system, and the Science Instrument Module (SIM). To achieve and retain the unprecedented imaging quality, it is critical that these three principal elements stay rigid and stable for the entire life time of the Chandra operation. Tracking the Chandra optical axis and aimpoint with respect to detector positions is the most relevant measurement for understanding telescope stability. The study shows that both the optical axis and the aimpoint has been drifting since Chandra launch. I will discuss the telescope focal-point, optical axis, aimpoint, their positiondrifts during the mission, the impact to Chandra operations, and the permanent default aimpoint, to be implemented in Chandra cycle 18.

  17. The microbiota-gut-brain axis in functional gastrointestinal disorders.

    Science.gov (United States)

    De Palma, Giada; Collins, Stephen M; Bercik, Premysl

    2014-01-01

    Functional gastrointestinal disorders (FGIDs) are highly prevalent and pose a significant burden on health care and society, and impact patients' quality of life. FGIDs comprise a heterogeneous group of disorders, with unclear underlying pathophysiology. They are considered to result from the interaction of altered gut physiology and psychological factors via the gut-brain axis, where brain and gut symptoms are reciprocally influencing each other's expression. Intestinal microbiota, as a part of the gut-brain axis, plays a central role in FGIDs. Patients with Irritable Bowel Syndrome, a prototype of FGIDs, display altered composition of the gut microbiota compared with healthy controls and benefit, at the gastrointestinal and psychological levels, from the use of probiotics and antibiotics. This review aims to recapitulate the available literature on FGIDs and microbiota-gut-brain axis.

  18. Microscope system with on axis programmable Fourier transform filtering

    Science.gov (United States)

    Martínez, José Luis; García-Martínez, Pascuala; Moreno, Ignacio

    2017-02-01

    We propose an on-axis microscope optical system to implement programmable optical Fourier transform image processing operations, taking advantage of phase and polarization modulation of a liquid crystal on silicon (LCOS) display. We use a Hamamatsu spatial light modulator (SLM), free of flickering, which therefore can be tuned to fully eliminate the zero order component of the encoded diffractive filter. This allows the realization of filtering operation on axis (as opposed to other systems in the literature that require operating off axis), therefore making use of the full space bandwidth provided by the SLM. The system is first demonstrated by implementing different optical processing operations based on phase-only blazed gratings such as phase contrast, band-pass filtering, or additive and substractive imaging. Then, a simple Differential interference contrast (DIC) imaging is obtained changing to a polarization modulation scheme, achieved simply by selecting a different incident state of polarization on the incident beam.

  19. Method of making a modular off-axis solar concentrator

    Energy Technology Data Exchange (ETDEWEB)

    Plesniak, Adam P.; Hall, John C.

    2017-05-23

    A method of making a solar concentrator may include forming a receiving wall having an elongated wall, a first side wall and a second side wall; attaching the first side wall and the second side wall to a reflecting wall to form a housing having an internal volume with an opening; forming a lip on the receiving wall and the reflecting wall; attaching a cover to the receiving wall and the reflecting wall at the lip to seal the opening into the internal volume, thereby creating a rigid structure; and mounting at least one receiver having at least one photovoltaic cell on the elongated wall to receive solar radiation entering the housing and reflected by the receiving wall, the receiver having an axis parallel with a surface normal of the photovoltaic cell, such that the axis is disposed at a non-zero angle relative to the vertical axis of the opening.

  20. Targeting the HER-kinase axis in cancer.

    Science.gov (United States)

    Gross, Mitchell E; Shazer, Ronald L; Agus, David B

    2004-02-01

    The human epidermal growth factor receptor (HER) family of receptor tyrosine kinases controls critical pathways involved in the differentiation, growth, division, and motility of normal epithelial cells. Most human solid tumors are of epithelial origin. The process of malignant transformation and progression in many cancers may depend on activation of ligands and receptors that function as part of the HER-kinase pathway. This signaling axis has earned increased attention because of the development of antibodies and small-molecule tyrosine kinase inhibitors that specifically target components of the HER-kinase axis for cancer therapy. This review focuses on the basic biology underlying HER-kinase pathway activation and the current state of development for agents that target this axis. In particular, the importance of pan-HER inhibitors is discussed.

  1. Complete Tri-Axis Magnetometer Calibration with a Gyro Auxiliary.

    Science.gov (United States)

    Yang, Deng; You, Zheng; Li, Bin; Duan, Wenrui; Yuan, Binwen

    2017-05-26

    Magnetometers combined with inertial sensors are widely used for orientation estimation, and calibrations are necessary to achieve high accuracy. This paper presents a complete tri-axis magnetometer calibration algorithm with a gyro auxiliary. The magnetic distortions and sensor errors, including the misalignment error between the magnetometer and assembled platform, are compensated after calibration. With the gyro auxiliary, the magnetometer linear interpolation outputs are calculated, and the error parameters are evaluated under linear operations of magnetometer interpolation outputs. The simulation and experiment are performed to illustrate the efficiency of the algorithm. After calibration, the heading errors calculated by magnetometers are reduced to 0.5° (1σ). This calibration algorithm can also be applied to tri-axis accelerometers whose error model is similar to tri-axis magnetometers.

  2. Computer Controlled Polishing of the Off-axis Aspheric Mirrors

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    In this paper, the manufacturing and testing procedures to make large off-axis aspherical mirrors are presented. The difficulties in polishing and testing for both circular-aperture and rectangular-aperture mirrors are previewed, and a possible solution is given. The two mirrors have been polished by means of CCOS, and the final accuracy is 25nm rms for 770mm×210mm rectangular mirror and 20nm rms for φ600mm circular mirror. These results just meet the optical tolerances specified by the designer, and the manufacturing and testing procedures presented here show good ability to make the large off-axis aspherical mirrors.

  3. A three-axis ultrasensitive accelerometer for space

    Science.gov (United States)

    Bernard, A.

    A three-axis ultrasensitive accelerometer ASTRE (Accelerometre Spatial Triaxial Electrostatique) is a simplified version of the GRADIO accelerometer designed for the ARISTOTELES mission, which operates by measuring the force provided by a three-axis electrostatic suspension of the proof-mass. It covers the g-spectrum from 10 exp -8 to 10 exp -4 in the frequency range dc to 5 Hz. A dedicated test bench was developed in order to preserve the accelerometer from the seismic noise. The paper presents the performance parameters of the ASTRE accelerometer and some of the design schemes.

  4. Three axis vector atomic magnetometer utilizing polarimetric technique.

    Science.gov (United States)

    Pradhan, Swarupananda

    2016-09-01

    The three axis vector magnetic field measurement based on the interaction of a single elliptically polarized light beam with an atomic system is described. The magnetic field direction dependent atomic responses are extracted by the polarimetric detection in combination with laser frequency modulation and magnetic field modulation techniques. The magnetometer geometry offers additional critical requirements like compact size and large dynamic range for space application. Further, the three axis magnetic field is measured using only the reflected signal (one polarization component) from the polarimeter and thus can be easily expanded to make spatial array of detectors and/or high sensitivity field gradient measurement as required for biomedical application.

  5. Three axis vector atomic magnetometer utilizing polarimetric technique

    CERN Document Server

    Pradhan, Swarupananda

    2016-01-01

    The three axis magnetic field measurement based on the interaction of a single elliptically polarized light beam with an atomic system is described. The magnetic field direction dependent atomic responses are extracted by the polarimetric detection in combination with laser frequency modulation and magnetic field modulation techniques. The magnetometer offers additional critical requirements like compact size and large dynamic range for space application. Further, the three axis magnetic field is measured using only reflected signal from the polarimeter, thus can be easily expanded to make spatial array of detectors or / and high sensitivity field gradient measurement as required for biomedical application.

  6. Efficient Path Query and Reasoning Method Based on Rare Axis

    Institute of Scientific and Technical Information of China (English)

    姜洋; 冯志勇; 王鑫马晓宁

    2015-01-01

    A new concept of rare axis based on statistical facts is proposed, and an evaluation algorithm is designed thereafter. For the nested regular expressions containing rare axes, the proposed algorithm can reduce its evaluation complexity from polynomial time to nearly linear time. The distributed technique is also employed to construct the navigation axis indexes for resource description framework (RDF) graph data. Experiment results in DrugBank and BioGRID show that this method can improve the query efficiency significantly while ensuring the accuracy and meet the query requirements on Web-scale RDF graph data.

  7. Fast satellite prediction for four-axis telescopes

    Institute of Scientific and Technical Information of China (English)

    林钦畅

    1996-01-01

    The features of the method are as follows: Adopting an optimum average small arc to four-axis prediction,the azimuth and altitude of the tracking axis need not be adjusted during the same observation procedure.The prediction has been used for three different types of telescopes for many years and all demands of users have been satisfied.In this method,the prediction contents were more than others.Separating the unknowns,the actual equations for operation were concise,and the needed machine time was much less,even for the prediction of multistation.

  8. Development of methodology for horizontal axis wind turbine dynamic analysis

    Science.gov (United States)

    Dugundji, J.

    1982-01-01

    Horizontal axis wind turbine dynamics were studied. The following findings are summarized: (1) review of the MOSTAS computer programs for dynamic analysis of horizontal axis wind turbines; (2) review of various analysis methods for rotating systems with periodic coefficients; (3) review of structural dynamics analysis tools for large wind turbine; (4) experiments for yaw characteristics of a rotating rotor; (5) development of a finite element model for rotors; (6) development of simple models for aeroelastics; and (7) development of simple models for stability and response of wind turbines on flexible towers.

  9. Three axis vector atomic magnetometer utilizing polarimetric technique

    Energy Technology Data Exchange (ETDEWEB)

    Pradhan, Swarupananda, E-mail: spradhan@barc.gov.in, E-mail: pradhans75@gmail.com [Laser and Plasma Technology Division, Bhabha Atomic Research Centre, Mumbai 400085, India and Homi Bhabha National Institute, Department of Atomic Energy, Mumbai 400094 (India)

    2016-09-15

    The three axis vector magnetic field measurement based on the interaction of a single elliptically polarized light beam with an atomic system is described. The magnetic field direction dependent atomic responses are extracted by the polarimetric detection in combination with laser frequency modulation and magnetic field modulation techniques. The magnetometer geometry offers additional critical requirements like compact size and large dynamic range for space application. Further, the three axis magnetic field is measured using only the reflected signal (one polarization component) from the polarimeter and thus can be easily expanded to make spatial array of detectors and/or high sensitivity field gradient measurement as required for biomedical application.

  10. Research on electromechanical resonance of two-axis tracking system

    Science.gov (United States)

    Zhao, Zhi-ming; Xue, Ying-jie; Zeng, Shu-qin; Li, Zhi-guo

    2017-02-01

    The multi-axes synchronous system about the spatial two-axis turntable is the key equipment for semi-physical simulation and test in aerospace. In this paper, the whole structure design of the turntable is created by using Solidworks, then putting the three-dimensional solid model into ANSYS to build the finite element model. The software ANSYS is used to do the simulation about the static and dynamic analysis of two-axis turntable. Based on the modal analysis, we can forecast the inherent frequencies and the mode of vibration during the launch conditions which is very important to the design and safety of the structure.

  11. Automatic Tool Path Generation for Robot Integrated Surface Sculpturing System

    Science.gov (United States)

    Zhu, Jiang; Suzuki, Ryo; Tanaka, Tomohisa; Saito, Yoshio

    In this paper, a surface sculpturing system based on 8-axis robot is proposed, the CAD/CAM software and tool path generation algorithm for this sculpturing system are presented. The 8-axis robot is composed of a 6-axis manipulator and a 2-axis worktable, it carves block of polystyrene foams by heated cutting tools. Multi-DOF (Degree of Freedom) robot benefits from the faster fashion than traditional RP (Rapid Prototyping) methods and more flexibility than CNC machining. With its flexibility driven from an 8-axis configuration, as well as efficient custom-developed software for rough cutting and finish cutting, this surface sculpturing system can carve sculptured surface accurately and efficiently.

  12. The psychology of HPA axis activation: Examining subjective emotional distress and control in a phobic fear exposure model.

    Science.gov (United States)

    Mayer, Stefanie E; Snodgrass, Michael; Liberzon, Israel; Briggs, Hedieh; Curtis, George C; Abelson, James L

    2017-02-09

    The HPA axis plays a key role in mediating the effects of "stress" on health, but clarifying mechanisms requires an understanding of psycho-biological linkages. There has long been an implicit assumption that subjective emotional distress (e.g., fear) should activate the HPA axis. Although this assumption was challenged 25 years ago (Curtis, 1976), laboratory studies in humans are limited. In this study we sought to replicate Curtis' findings and extend it by investigating if presence or absence of stressor control shapes HPA axis reactivity in a phobic fear exposure model. We recruited 19-45-year-old specific phobia participants (n=32 spider/snake phobia; n=14 claustrophobia) and gradually exposed them to their feared object or situation while measuring hormonal (ACTH and cortisol) and subjective (emotional distress, perceived control) responses. Utilizing a dyadic yoked design, we compared HPA reactivity when the pace of exposure was controlled by participants to identical exposure given to matched participants in the absence of control. Results showed that phobic fear exposure generated intense emotional distress without a corresponding increase in HPA axis activity. Although our actual manipulation of control failed to impact HPA responses, perceived control during exposure was associated with lower cortisol, an effect that was moderated by actual availability of stressor control. Our findings replicate Curtis' findings and challenge the still common but unsupported assumption that HPA axis activity reflects subjective distress. These results also highlight the importance of both perceived and actual aspects of stressor control in understanding what is truly "stressful" to the HPA axis system.

  13. Instant Generation

    Science.gov (United States)

    Loveland, Elaina

    2017-01-01

    Generation Z students (born between 1995-2010) have replaced millennials on college campuses. Generation Z students are entrepreneurial, desire practical skills with their education, and are concerned about the cost of college. This article presents what need to be known about this new generation of students.

  14. Trapped field internal dipole superconducting motor generator

    Energy Technology Data Exchange (ETDEWEB)

    Hull, John R. (Downers Grove, IL)

    2001-01-01

    A motor generator including a high temperature superconductor rotor and an internally disposed coil assembly. The motor generator superconductor rotor is constructed of a plurality of superconductor elements magnetized to produce a dipole field. The coil assembly can be either a conventional conductor or a high temperature superconductor. The superconductor rotor elements include a magnetization direction and c-axis for the crystals of the elements and which is oriented along the magnetization direction.

  15. Assessing behavioural effects of chronic HPA axis activation using conditional CRH-overexpressing mice.

    Science.gov (United States)

    Dedic, Nina; Touma, Chadi; Romanowski, Cristoph P; Schieven, Marcel; Kühne, Claudia; Ableitner, Martin; Lu, Ailing; Holsboer, Florian; Wurst, Wolfgang; Kimura, Mayumi; Deussing, Jan M

    2012-07-01

    The corticotropin-releasing hormone (CRH) and its cognate receptors have been implicated in the pathophysiology of stress-related disorders. Hypersecretion of central CRH and elevated glucocorticoid levels, as a consequence of impaired feedback control, have been shown to accompany mood and anxiety disorders. However, a clear discrimination of direct effects of centrally hypersecreted CRH from those resulting from HPA axis activation has been difficult. Applying a conditional strategy, we have generated two conditional CRH-overexpressing mouse lines: CRH-COE ( Del ) mice overexpress CRH throughout the body, while CRH-COE ( APit ) mice selectively overexpress CRH in the anterior and intermediate lobe of the pituitary. Both mouse lines show increased basal plasma corticosterone levels and consequently develop signs of Cushing's syndrome. However, while mice ubiquitously overexpressing CRH exhibited increased anxiety-related behaviour, overexpression of CRH in the pituitary did not produce alterations in emotional behaviour. These results suggest that chronic hypercorticosteroidism alone is not sufficient to alter anxiety-related behaviour but rather that central CRH hyperdrive on its own or in combination with elevated glucocorticoids is responsible for the increase in anxiety-related behaviour. In conclusion, the generated mouse lines represent valuable animal models to study the consequences of chronic CRH overproduction and HPA axis activation.

  16. Traceable Calibration of the 3 axis Thrust Vector in the mN range

    Science.gov (United States)

    Hughes, B.; Oldfield, S.

    2004-10-01

    The possibility of measuring the three force components i.e. the main axial component and the two orthogonal radial components, generated by an electric propulsion system is important for two reasons. Firstly, to assess the impact of spacecraft/propulsion system integration issues, for example to verify the alignment of the thrust vector with the spacecraft centre-of-mass for spacecraft stability. Secondly, to operate the thruster properly during flight, for example to determine the thrust vector relative to the mechanical axis of the thruster. Furthermore, a three-axis measurement capability will be useful for the experimental performance verification of the next generation of vectored electric propulsion devices, especially regarding the many unresolved issues connected with indirect thrust measurement using electrostatic probes. The capability to monitor thrust vector drift in real time and with significant bandwidth is also important. Thus enabling vector drift during thruster warm-up, to be measured, and the response of vectored thrusters to change in vector demand can be assessed. In this paper we describe the design, construction and testing of an instrument proof of concept. The instrument was designed to accommodate a dummy thruster mass of 0.5 kg and operate in the 0 to 10 mN range. The directional resolution that has been demonstrated is better than 0.05 ° in both axes when operating at full thrust.

  17. Submersible Generator for Marine Hydrokinetics

    Energy Technology Data Exchange (ETDEWEB)

    Cinq-Mars, Robert S; Burke, Timothy; Irish, James; Gustafson, Brian; Kirtley, James; Alawa, Aiman

    2011-09-01

    A submersible generator was designed as a distinct and critical subassembly of marine hydrokinetics systems, specifically tidal and stream energy conversion. The generator is designed to work with both vertical and horizontal axis turbines. The final product is a high-pole-count, radial-flux, permanent magnet, rim mounted generator, initially rated at twenty kilowatts in a two-meter-per-second flow, and designed to leverage established and simple manufacturing processes. The generator was designed to work with a 3 meter by 7 meter Gorlov Helical Turbine or a marine hydrokinetic version of the FloDesign wind turbine. The team consisted of experienced motor/generator design engineers with cooperation from major US component suppliers (magnetics, coil winding and electrical steel laminations). Support for this effort was provided by Lucid Energy Technologies and FloDesign, Inc. The following tasks were completed: Identified the conditions and requirements for MHK generators. Defined a methodology for sizing and rating MHK systems. Selected an MHK generator topology and form factor. Completed electromechanical design of submersible generator capable of coupling to multiple turbine styles. Investigated MHK generator manufacturing requirements. Reviewed cost implications and financial viability. Completed final reporting and deliverables

  18. Third Harmonic Generation of a Short Pulse Laser in a Tunnel Ionizing Plasma: Effect of Self-Defocusing

    OpenAIRE

    Niti Kant

    2013-01-01

    Third harmonic generation of a Gaussian short pulse laser in a tunnel ionizing plasma is investigated. A Gaussian short pulse laser propagating through a tunnel ionizing plasma generates third harmonic wave. Inhomogeneity of the electric field along the wavefront of the fundamental laser pulse causes more ionization along the axis of propagation while less ionization off axis, leading to strong density gradient with its maximum on the axis of propagation. The medium acts like a diverging lens...

  19. Parametric Study on a Horizontal Axis Wind Turbine Proposed for Water Pumping

    Directory of Open Access Journals (Sweden)

    Dr. Abdullateef A. Jadallah

    2014-01-01

    Full Text Available Water pumping is considered an economically competitive sustainable process of providing water to communities, rural areas and livestock's. A parametric analysis on HAWT is carried out to explore the influence of the performance parameters on the power generated and withdrawal quantity of water. Effect of wind speed, radius of rotor, ambient condition, well depth, and efficiencies of turbine, generator and the pump were studied and reflected in important generalized performance maps. These performance graphs are valuable in best understanding of on‐design and off‐ design constraints of the horizontal axis wind turbine in water pumping. The blade geometry was also studied. Results showed the reasonable range of wind turbine performance and the corresponding water discharge within the abovementioned constraints. Rating and the effect of pitch angle on discharged water are also presented. Methodology necessary to achieve the abovementioned results is processed by a computer program written in Matlab

  20. Analysis of the Drivetrain Performance of a Large Horizontal-Axis Wind Turbine: An Aeroelastic Approach

    DEFF Research Database (Denmark)

    Gebhardt, Cristian; Preidikman, Sergio; Massa, Julio C

    2010-01-01

    blades’, the drivetrain and the generator. The blades are the part of the turbine that touches energy in the wind and rotates about an axis. Extracting energy from the wind is typically accomplished by first mechanically converting the velocity of the wind into a rotational motion of the wind turbine...... by means of the rotor blades, and then converting the rotational energy of the rotor blades into electrical energy by using a generator. The amount of available energy which the wind transfers to the rotor depends on the mass density of the air, the sweep area of the rotor blades, and the wind speed......Due to increasing environmental concern, and approaching limits to fossil fuel consumption, green sources of energy are gaining interest. Among the several energy sources being explored, wind energy shows much promise in selected areas where the average wind speeds is high. Wind turbines are used...

  1. AxiSEM: Exploiting structural complexity for efficient wave propagation across the scales

    Science.gov (United States)

    Nissen-Meyer, Tarje; van Driel, Martin; Leng, Kuangdai; Stähler, Simon; Krischer, Lion; Hosseini, Kasra

    2016-04-01

    Our open-source seismic modeling method AxiSEM (www.axisem.info) is presented a backbone for numerous further extensions, including accurate and efficient wave propagation in 3D Earth models, a database mode (www.instaseis.net), local domains, hybrid methods, and waveform sensitivity kernels for tomography. Our general mantra is to enable wave propagation across the observable frequency spectrum in a most efficient manner by adapting the methodology directly to the level of structural complexity, in the vein of Occam's razor. The basic AxiSEM approach relies upon axisymmetric (including spherically symmetric) models, thereby satisfying a large fraction of observable data. The benefit of this method stems from the resultant dimensional collapse to two numerical dimensions, whereby the third azimuthal dimension is tackled analytically. For high-frequency wave propagation, this leads to 3-4 orders of magnitude speedup in computational cost compared to 3D domain discretizations. AxiSEM is highly scalable anywhere between laptops and supercomputers, and includes novel, optimized implementations of viscoelasticity and anisotropy. We present benchmarks, data comparisons, a range of unique applications from inner-core anisotropy to noise modeling and lowermost mantle structures. 1D structures are exploited by instaseis, a methodology to extract full, broadband and accurate waveforms instantaneously from wavefield databases computed with AxiSEM. A webservice built on instaseis ("syngine") has been launched at IRIS (see abstract EGU2016-8190) to generate on-demand synthetics up to 1Hz for prominent Earth models. 3D structures are tackled by our recent extension AxiSEM3D: We expand the wavefield in the azimuthal dimension in Fourier series, leading to a drastic computational cost speedup compared to classic 3D methods (up to a factor of 100), especially in the high-frequency regime. We will show benchmarks for typical global tomographic models and sketch our approach to

  2. Fast and accurate measurement of on-axis gain and on-axis polarization at a finite distance

    DEFF Research Database (Denmark)

    Pivnenko, S.; Breinbjerg, O.

    2013-01-01

    In this paper, a technique for fast and accurate measurement of on-axis gain and on-axis polarization characteristics of antennas, such as Standard Gain Horns, compact range feed horns, and near-field probes, is described. The proposed gain determination procedure is a modification of the far-field...... orientations versus a polarization calibrated probe. A complete set of measurements for one AUT takes less than two hours. The measurement uncertainty for the gain is comparable to the one obtained with the near-field substitution technique and typically does not exceed 0.1 dB (1 sigma)....

  3. Thermally induced reversible easy axis rotations in permalloy thin films

    NARCIS (Netherlands)

    Horsthuis, Winfried H.G.; Eijkel, Kees J.M.; Ridder, de René M.; Leeuwis, Henk

    1988-01-01

    The thermal stability of the easy axis orientation in thin Permalloy films was studied. This orientation was measured by two methods, i.e. the magneto-optic Kerr effect and a novel measurement scheme based on magnetoresistive effects. It appeared that even for small temperature changes rotations of

  4. The gut microbiome, probiotics, bile acids axis, and human health.

    Science.gov (United States)

    Jones, Mitchell Lawrence; Tomaro-Duchesneau, Catherine; Prakash, Satya

    2014-06-01

    The human gut microbiome produces potent ligands to bile acid receptors, and probiotics could act as therapeutics of bile acid dysmetabolism. A recent study in Cell Reports demonstrates that probiotic VSL#3 affects bile acid deconjugation and excretion, as well as the gut-liver FXR-FGF15 axis.

  5. Stereo PIV Experiments on Horizontal Axis Wind Turbine Rotor Model

    NARCIS (Netherlands)

    Akay, B.; Micallef, D.; Ferreira, C.S.; Van Bussel, G.J.W.

    2011-01-01

    This paper sets out to describe the measurements and computations to construct three components of velocity field around the blade. The primary aim of the measurements was to gain insight into the physics of the flow field produced by a horizontal axis wind turbine-HAWT blade. Stereo Particle Image

  6. All-optical, Three-axis Fiber Laser Magnetometer

    Science.gov (United States)

    2012-04-16

    E-1 1.  INTRODUCTION ...achieved with other magnetic field sensing technologies such as those based on flux gates and fiber optic magnetostrictive sensors. The deployed...ALL-OPTICAL, THREE-AXIS FIBER LASER MAGNETOMETER 1. INTRODUCTION This report describes the development of an undersea fiber optic magnetometer

  7. Genetic disorders in the growth hormone - IGF-I Axis

    NARCIS (Netherlands)

    Walenkamp, Maria Josephina Elisabeth

    2007-01-01

    Growth is a complex process, regulated by multiple external and internal factors. Deviation from the normal growth pattern can be one of the first manifestations of an underlying disorder, disrupting the normal growth process. The growth hormone – IGF-I axis plays a key role in regulating this growt

  8. Targeting the gut-liver axis in cirrhosis

    DEFF Research Database (Denmark)

    Madsen, Bjørn S; Havelund, Troels; Krag, Aleksander

    2013-01-01

    The gut-liver axis in cirrhosis and portal hypertension is gaining increasing attention as a key pathophysiological mechanism responsible for progression of liver failure and development of complications such as spontaneous infections and hepatocellular carcinoma. Antibiotics and non-selective β-...

  9. On lifting line analysis of horizontal axis windturbines

    Science.gov (United States)

    Politis, G. K.; Loukakis, T. A.

    A convergent iteration scheme for lifting line performance analysis of horizontal axis windturbines is presented. Lifting line correction factors are introduced and compared with those of Prandtl and Goldstein. Lifting line and strip theory formulations are applied for the calculation of performance for two windturbines. Differences of engineering importance are shown to exist in the prediction of the Power coefficient.

  10. A novel dual-axis reconstruction algorithm for electron tomography

    Energy Technology Data Exchange (ETDEWEB)

    Tong, Jenna; Midgley, Paul [Department of Materials Science and Metallurgy, University of Cambridge, Pembroke Street, Cambridge, CB2 3QZ (United Kingdom)

    2006-02-22

    A new algorithm for computing electron microscopy tomograms which combines iterative methods with dual-axis geometry is presented. Initial modelling using test data shows several improvements over both the weighted back-projection (WBP) and Simultaneous Iterative Reconstruction Technique (SIRT) method, and, with increased stability and tomogram fidelity under high-noise conditions.

  11. Brain-gut-microbiota axis in Parkinson's disease.

    Science.gov (United States)

    Mulak, Agata; Bonaz, Bruno

    2015-10-07

    Parkinson's disease (PD) is characterized by alpha-synucleinopathy that affects all levels of the brain-gut axis including the central, autonomic, and enteric nervous systems. Recently, it has been recognized that the brain-gut axis interactions are significantly modulated by the gut microbiota via immunological, neuroendocrine, and direct neural mechanisms. Dysregulation of the brain-gut-microbiota axis in PD may be associated with gastrointestinal manifestations frequently preceding motor symptoms, as well as with the pathogenesis of PD itself, supporting the hypothesis that the pathological process is spread from the gut to the brain. Excessive stimulation of the innate immune system resulting from gut dysbiosis and/or small intestinal bacterial overgrowth and increased intestinal permeability may induce systemic inflammation, while activation of enteric neurons and enteric glial cells may contribute to the initiation of alpha-synuclein misfolding. Additionally, the adaptive immune system may be disturbed by bacterial proteins cross-reacting with human antigens. A better understanding of the brain-gut-microbiota axis interactions should bring a new insight in the pathophysiology of PD and permit an earlier diagnosis with a focus on peripheral biomarkers within the enteric nervous system. Novel therapeutic options aimed at modifying the gut microbiota composition and enhancing the intestinal epithelial barrier integrity in PD patients could influence the initial step of the following cascade of neurodegeneration in PD.

  12. Stereo PIV Experiments on Horizontal Axis Wind Turbine Rotor Model

    NARCIS (Netherlands)

    Akay, B.; Micallef, D.; Ferreira, C.S.; Van Bussel, G.J.W.

    2011-01-01

    This paper sets out to describe the measurements and computations to construct three components of velocity field around the blade. The primary aim of the measurements was to gain insight into the physics of the flow field produced by a horizontal axis wind turbine-HAWT blade. Stereo Particle Image

  13. Tilted axis rotation in odd-odd {sup 164}Tm

    Energy Technology Data Exchange (ETDEWEB)

    Reviol, W.; Riedinger, L.L.; Wang, X.Z.; Zhang, J.Y. [Univ. of Tennessee, Knoxville, TN (United States)] [and others

    1996-12-31

    Ten band structures are observed in {sup 164}Tm, among them sets of parallel and anti-parallel couplings of the proton and neutron spins. The Tilted Axis Cranking scheme is applied for the first time to an odd-odd nucleus in a prominent region of nuclear deformation.

  14. Microbiota regulation of the Mammalian gut-brain axis.

    Science.gov (United States)

    Burokas, Aurelijus; Moloney, Rachel D; Dinan, Timothy G; Cryan, John F

    2015-01-01

    The realization that the microbiota-gut-brain axis plays a critical role in health and disease has emerged over the past decade. The brain-gut axis is a bidirectional communication system between the central nervous system (CNS) and the gastrointestinal tract. Regulation of the microbiota-brain-gut axis is essential for maintaining homeostasis, including that of the CNS. The routes of this communication are not fully elucidated but include neural, humoral, immune, and metabolic pathways. A number of approaches have been used to interrogate this axis including the use of germ-free animals, probiotic agents, antibiotics, or animals exposed to pathogenic bacterial infections. Together, it is clear that the gut microbiota can be a key regulator of mood, cognition, pain, and obesity. Understanding microbiota-brain interactions is an exciting area of research which may contribute new insights into individual variations in cognition, personality, mood, sleep, and eating behavior, and how they contribute to a range of neuropsychiatric diseases ranging from affective disorders to autism and schizophrenia. Finally, the concept of psychobiotics, bacterial-based interventions with mental health benefit, is also emerging.

  15. Alfven eigenmode structure during off-axis neutral beam injection

    NARCIS (Netherlands)

    Tobias, B.; Bass, E. M.; Classen, I.G.J.; Domier, C.W.; Grierson, B. A.; Heidbrink, W. W.; N C Luhmann Jr.,; Nazikian, R.; Park, H. K.; Spong, D. A.; VanZeeland, M. A.

    2012-01-01

    The spatial structure of Alfven eigenmodes on the DIII-D tokamak is compared for contrasting fast ion deposition profiles resulting from on- and off-axis neutral beam injection (NBI). In both cases, poloidal mode rotation and eigenmode twist, or radial phase variation, are correlated with the direct

  16. Comparison of aerodynamic models for Vertical Axis Wind Turbines

    NARCIS (Netherlands)

    Simao Ferreira, C.J.; Aagaard Madsen, H.; Barone, M.; Roscher, B.; Deglaire, P.; Arduin, I.

    2014-01-01

    Multi-megawatt Vertical Axis Wind Turbines (VAWTs) are experiencing an increased interest for floating offshore applications. However, VAWT development is hindered by the lack of fast, accurate and validated simulation models. This work compares six different numerical models for VAWTS: a multiple s

  17. On the Turbulent Mixing in Horizontal Axis Wind Turbine Wakes

    NARCIS (Netherlands)

    Lignarolo, L.E.M.

    2016-01-01

    The wake flow of a horizontal axis wind turbine is characterised by lower wind speed and higher turbulence than the free-stream conditions. When clustered in large wind farms, wind turbines regularly operate inside the wake of one or more upstream machines. This is a major cause of energy production

  18. The Advanced X-ray Imaging Satellite (AXIS)

    Science.gov (United States)

    Reynolds, Christopher S.; Mushotzky, Richard

    2017-08-01

    The Advanced X-ray Imaging Satellite (AXIS) will follow in the footsteps of the spectacularly successful Chandra X-ray Observatory with similar or higher angular resolution and an order of magnitude more collecting area in the 0.3-10keV band. These capabilities will enable major advances in many of the most active areas of astrophysics, including (i) mapping event horizon scale structure in AGN accretion disks and the determination of supermassive black hole (SMBH) spins through monitoring of gravitationally-microlensed quasars; (ii) dramatically deepening our understanding of AGN feedback in galaxies and galaxy clusters out to high-z through the direct imaging of AGN winds and the interaction of jets with the hot interstellar/intracluster medium; (iii) understanding the fueling of AGN by probing hot flows inside of the SMBH sphere of influence; (iv) obtaining geometric distance measurements using dust scattering halos. With a nominal 2028 launch, AXIS will be enormously synergistic with LSST, ALMA, WFIRST and ATHENA, and will be a valuable precursor to Lynx. AXIS is enabled by breakthroughs in the construction of light-weight X-ray optics from mono-crystalline silicon blocks, building on recent developments in the semiconductor industry. Here, we describe the straw-man concept for AXIS, some of the high profile science that this observatory will address, and how you can become involved.

  19. On the Turbulent Mixing in Horizontal Axis Wind Turbine Wakes

    NARCIS (Netherlands)

    Lignarolo, L.E.M.

    2016-01-01

    The wake flow of a horizontal axis wind turbine is characterised by lower wind speed and higher turbulence than the free-stream conditions. When clustered in large wind farms, wind turbines regularly operate inside the wake of one or more upstream machines. This is a major cause of energy production

  20. The microbiome‐gut‐brain axis: from bowel to behavior

    National Research Council Canada - National Science Library

    Cryan, J. F; O’Mahony, S. M

    2011-01-01

    ... microbiome greatly impacts on gut‐brain communication leading to the coining of the phrase the brain‐gut enteric microbiota axis (illustrated in Fig. 1 ). The exact mechanisms governing such communication are unclear and most studies to date focus on the impact of altered signaling from the brain to the gut. Recent emerging studies are investigating t...

  1. Transport Phenomena of Off-Axis Sputtering Deposition

    Science.gov (United States)

    Zhu, S.; Su, C. H.; Lehoczky, S. L.; Zhang, S.; Whitaker, Ann F. (Technical Monitor)

    2001-01-01

    Various high quality epitaxial films, especially oxides, have been synthesized using off-axis sputtering deposition. In this presentation, we report the experiment results of ZnO films grown by the off-axis sputtering deposition. Films were synthesized in temperatures ranged from room temperature to 600 C, and pressures from 5 mTorr to 150 mTorr. Film growth rate was measured by surface profilometer, ellipsometer, and wavelength dispersive spectrometry. Due to the collisions between the sputtered species and the residue gases, the kinetic energy of species was reduced and the transport of depositing species changed from a ballistic movement for low pressure to a diffuse drift for high pressure in which the transport species were almost thermalized. The measurements show an increase of growth rates along the gravity vector when the Knodson (Knudsen??) number of transport species is less than 0.05, which suggests that gravity affected the transport characterization in off-axis sputtering deposition. Because the product of pressure (p) and travel distance (d) of sputtered species, p exceeds several mTorr-cm during film deposition, the classical simulations for sputtering process in high vacuum system may not be applied. Based on these experimental measurements, a transport process of the off-axis sputtering deposition is proposed. Several methods including the Monte Carlo method and gravity-driven flow dynamics simulation will be discussed.

  2. Serotonergic stimulation of the rat hypothalamo-pituitary-adrenal axis

    DEFF Research Database (Denmark)

    Mikkelsen, Jens D; Hay-Schmidt, Anders; Kiss, Alexander

    2004-01-01

    Acute stimulation of the hypothalamo-pituitary-adrenal (HPA) axis by selective serotonin reuptake inhibitors (SSRIs) is mediated by several postsynaptic 5-HT receptor subtypes. Activation of 5-HT(1A) and 5-HT(2A) receptors increases plasma corticosterone levels, and it is likely that these recept...

  3. Vertical-axis wind turbines -- The current status of an old technology

    Energy Technology Data Exchange (ETDEWEB)

    Berg, D.E.

    1996-12-31

    Vertical-axis wind turbine technology is not well understood, even though the earliest wind machines rotated about a vertical axis. The operating environment of a vertical-axis wind turbine is quite complex, but detailed analysis capabilities have been developed and verified over the last 30 years. Although vertical-axis technology has not been widely commercialized, it exhibits both advantages and disadvantages compared to horizontal-axis technology, and in some applications, it appears to offer significant advantages.

  4. DARHT Axis-I Diode Simulations II: Geometrical Scaling

    Energy Technology Data Exchange (ETDEWEB)

    Ekdahl, Carl A. Jr. [Los Alamos National Laboratory

    2012-06-14

    Flash radiography of large hydrodynamic experiments driven by high explosives is a venerable diagnostic technique in use at many laboratories. Many of the largest hydrodynamic experiments study mockups of nuclear weapons, and are often called hydrotests for short. The dual-axis radiography for hydrodynamic testing (DARHT) facility uses two electron linear-induction accelerators (LIA) to produce the radiographic source spots for perpendicular views of a hydrotest. The first of these LIAs produces a single pulse, with a fixed {approx}60-ns pulsewidth. The second axis LIA produces as many as four pulses within 1.6-{micro}s, with variable pulsewidths and separation. There are a wide variety of hydrotest geometries, each with a unique radiographic requirement, so there is a need to adjust the radiographic dose for the best images. This can be accomplished on the second axis by simply adjusting the pulsewidths, but is more problematic on the first axis. Changing the beam energy or introducing radiation attenuation also changes the spectrum, which is undesirable. Moreover, using radiation attenuation introduces significant blur, increasing the effective spot size. The dose can also be adjusted by changing the beam kinetic energy. This is a very sensitive method, because the dose scales as the {approx}2.8 power of the energy, but it would require retuning the accelerator. This leaves manipulating the beam current as the best means for adjusting the dose, and one way to do this is to change the size of the cathode. This method has been proposed, and is being tested. This article describes simulations undertaken to develop scaling laws for use as design tools in changing the Axis-1 beam current by changing the cathode size.

  5. The manufacturing and metrology of off-axis mirrors

    Science.gov (United States)

    Penzkofer, Karlheinz; Rascher, Rolf; Küpper, Lutz; Liebl, Johannes

    2015-10-01

    Especially in the area of the large mirror manufacturing only a few manufacturers are capable to produce optical surfaces of high quality. Therefore a deterministic process should be developed in the project IFasO. In the field of telescope optics off-axis optical systems are becoming increasingly important. These systems try to avoid an obstructing of the incoming light by moving the secondary mirror out of the primary mirror's optical axis. This advantage leads to an increasing market for this type of optical surface. Until now off-axis mirrors were difficult or almost impossible to produce. With the processes developed in IFasO, high quality mirrors become possible. For this reason, this paper describes the manufacturing of off-axis surfaces and its problems. The mirror production used in the project IFasO is based on the specific design of the CNC center developed by the company Optotech. This center UPG2000 is capable of grinding, polishing, sagitta measurement and interferometric measurement in one mounting of the specimen. Usually a large optics has to be transported during their manufacturing after every individual process step. There is always a risk of damage of the specimen. The exact orientation of the surface relatively to the tool position is also required. This takes a huge amount of time and makes up most of the production time. In this presentation the use of UPG2000 and the next steps within the process development are described. In the current status the manufacturing of large off-axis elements with a PV < λ/10 rms is reproducible.

  6. Comparative transcriptomic analysis of developing cotton cotyledons and embryo axis.

    Directory of Open Access Journals (Sweden)

    Xiaoming Jiao

    Full Text Available BACKGROUND: As a by product of higher value cotton fibre, cotton seed has been increasingly recognised to have excellent potential as a source of additional food, feed, biofuel stock and even a renewable platform for the production of many diverse biological molecules for agriculture and industrial enterprises. The large size difference between cotyledon and embryo axis that make up a cotton seed results in the under-representation of embryo axis gene transcript levels in whole seed embryo samples. Therefore, the determination of gene transcript levels in the cotyledons and embryo axes separately should lead to a better understanding of metabolism in these two developmentally diverse tissues. RESULTS: A comparative study of transcriptome changes between cotton developing cotyledon and embryo axis has been carried out. 17,384 unigenes (20.74% of all the unigenes were differentially expressed in the two adjacent embryo tissues, and among them, 7,727 unigenes (44.45% were down-regulated and 9,657 unigenes (55.55% were up-regulated in cotyledon. CONCLUSIONS: Our study has provided a comprehensive dataset that documents the dynamics of the transcriptome at the mid-maturity of cotton seed development and in discrete seed tissues, including embryo axis and cotyledon tissues. The results showed that cotton seed is subject to many transcriptome variations in these two tissue types and the differential gene expression between cotton embryo axis and cotyledon uncovered in our study should provide an important starting point for understanding how gene activity is coordinated during seed development to make a seed. Further, the identification of genes involved in rapid metabolite accumulation stage of seed development will extend our understanding of the complex molecular and cellular events in these developmental processes and provide a foundation for future studies on the metabolism, embryo differentiation of cotton and other dicot oilseed crops.

  7. Velocity measurement of model vertical axis wind turbines

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, D.A.; McWilliam, M. [Waterloo Univ., ON (Canada). Dept. of Mechanical Engineering

    2006-07-01

    An increasingly popular solution to future energy demand is wind energy. Wind turbine designs can be grouped according to their axis of rotation, either horizontal or vertical. Horizontal axis wind turbines have higher power output in a good wind regime than vertical axis turbines and are used in most commercial class designs. Vertical axis Savonius-based wind turbine designs are still widely used in some applications because of their simplistic design and low wind speed performance. There are many design variables that must be considered in order to optimize the power output in a given wind regime in a typical wind turbine design. Using particle image velocimetry, a study of the air flow around five different model vertical axis wind turbines was conducted in a closed loop wind tunnel. A standard Savonius design with two semi-circular blades overlapping, and two variations of this design, a deep blade and a shallow blade design were among the turbine models included in this study. It also evaluated alternate designs that attempt to increase the performance of the standard design by allowing compound blade curvature. Measurements were collected at a constant phase angle and also at random rotor orientations. It was found that evaluation of the flow patterns and measured velocities revealed consistent and stable flow patterns at any given phase angle. Large scale flow structures are evident in all designs such as vortices shed from blade surfaces. An important performance parameter was considered to be the ability of the flow to remain attached to the forward blade and redirect and reorient the flow to the following blade. 6 refs., 18 figs.

  8. Wind Generators

    Science.gov (United States)

    1989-01-01

    When Enerpro, Inc. president, Frank J. Bourbeau, attempted to file a patent on a system for synchronizing a wind generator to the electric utility grid, he discovered Marshall Space Flight Center's Frank Nola's power factor controller. Bourbeau advanced the technology and received a NASA license and a patent for his Auto Synchronous Controller (ASC). The ASC reduces generator "inrush current," which occurs when large generators are abruptly brought on line. It controls voltage so the generator is smoothly connected to the utility grid when it reaches its synchronous speed, protecting the components from inrush current damage. Generator efficiency is also increased in light winds by applying lower than rated voltage. Wind energy is utilized to drive turbines to generate electricity for utility companies.

  9. Rippled disc electrostatic generator/motor configurations utilizing magnetic insulation

    Energy Technology Data Exchange (ETDEWEB)

    Post, Richard F

    2017-04-04

    Electrostatic generators/motors designs are provided that generally may include a first rippled stator centered about a longitudinal axis; a second rippled stator centered about the axis, a first rippled rotor centered about the axis and located between the first rippled stator and the second rippled stator. A magnetic field having field lines about parallel with the average plane of at least one of the first rippled stator or the second rippled stator is provided with either a Halbach array configuration or a conductor array configuration.

  10. Simulation of flow over double-element airfoil and wind tunnel test for use in vertical axis wind turbine

    Science.gov (United States)

    Chougule, Prasad; Nielsen, Søren R. K.

    2014-06-01

    Nowadays, small vertical axis wind turbines are receiving more attention due to their suitability in micro-electricity generation. There are few vertical axis wind turbine designs with good power curve. However, the efficiency of power extraction has not been improved. Therefore, an attempt has been made to utilize high lift technology for vertical axis wind turbines in order to improve power efficiency. High lift is obtained by double-element airfoil mainly used in aeroplane wing design. In this current work a low Reynolds number airfoil is selected to design a double-element airfoil blade for use in vertical axis wind turbine to improve the power efficiency. Double-element airfoil blade design consists of a main airfoil and a slat airfoil. Orientation of slat airfoil is a parameter of investigation in this paper and air flow simulation over double-element airfoil. With primary wind tunnel test an orientation parameter for the slat airfoil is initially obtained. Further a computational fluid dynamics (CFD) has been used to obtain the aerodynamic characteristics of double-element airfoil. The CFD simulations were carried out using ANSYS CFX software. It is observed that there is an increase in the lift coefficient by 26% for single-element airfoil at analysed conditions. The CFD simulation results were validated with wind tunnel tests. It is also observe that by selecting proper airfoil configuration and blade sizes an increase in lift coefficient can further be achieved.

  11. Rainfall generation

    Science.gov (United States)

    Sharma, Ashish; Mehrotra, Raj

    This chapter presents an overview of methods for stochastic generation of rainfall at annual to subdaily time scales, at single- to multiple-point locations, and in a changing climatic regime. Stochastic rainfall generators are used to provide inputs for risk assessment of natural or engineering systems that can undergo failure under sustained (high or low) extremes. As a result, generation of rainfall has evolved to provide options that adequately represent such conditions, leading to sequences that exhibit low-frequency variability of a nature similar to the observed rainfall. The chapter consists of three key sections: the first two outlining approaches for rainfall generation using endogenous predictor variables and the third highlighting approaches for generation using exogenous predictors often simulated to represent future climatic conditions. The first section presents approaches for generation of annual and seasonal rainfall and daily rainfall, both at single-point locations and multiple sites, with an emphasis on alternatives that ensure appropriate representation of low-frequency variability in the generated rainfall sequences. The second section highlights advancements in the subdaily rainfall generation procedures including commonly used approaches for daily to subdaily rainfall generation. The final section (generation using exogenous predictors) presents a range of alternatives for stochastic downscaling of rainfall for climate change impact assessments of natural and engineering systems. We conclude the chapter by outlining some of the key challenges that remain to be addressed, especially in generation under climate change conditions, with an emphasis on the importance of incorporating uncertainty present in both measurements and models, in the rainfall sequences that are generated.

  12. Control system for bearingless motor-generator

    Science.gov (United States)

    Kascak, Peter E. (Inventor); Jansen, Ralph H. (Inventor); Dever, Timothy P. (Inventor)

    2010-01-01

    A control system for an electromagnetic rotary drive for bearingless motor-generators comprises a winding configuration comprising a plurality of individual pole pairs through which phase current flows, each phase current producing both a lateral force and a torque. A motor-generator comprises a stator, a rotor supported for movement relative to the stator, and a control system. The motor-generator comprises a winding configuration supported by the stator. The winding configuration comprises at least three pole pairs through which phase current flows resulting in three three-phase systems. Each phase system has a first rotor reference frame axis current that produces a levitating force with no average torque and a second rotor reference frame axis current that produces torque.

  13. Performance analysis of voltage regulation in diesel-wind generation

    African Journals Online (AJOL)

    user

    wind stream in the spin of the turbine the spin is the mechanical energy, now this mechanical energy is ... magnet synchronous generator is also their according to the electrical power generation these ..... Rotor flux component in q axis φdr.

  14. Generative Semantics

    Science.gov (United States)

    Bagha, Karim Nazari

    2011-01-01

    Generative semantics is (or perhaps was) a research program within linguistics, initiated by the work of George Lakoff, John R. Ross, Paul Postal and later McCawley. The approach developed out of transformational generative grammar in the mid 1960s, but stood largely in opposition to work by Noam Chomsky and his students. The nature and genesis of…

  15. Central regulation of the hypothalamo-pituitary-thyroid (HPT) axis: focus on clinical aspects.

    Science.gov (United States)

    Fliers, E; Boelen, A; van Trotsenburg, A S P

    2014-01-01

    The hypothalamus is the most prominent brain region involved in setpoint regulation of the thyroid axis. It generates the diurnal thyroid-stimulating hormone (TSH) rhythm, and it plays a central role in the adaptation of the thyroid axis to environmental factors such as caloric deprivation or infection. Many studies, including studies in human post-mortem tissue samples, have confirmed a key role for the thyrotropin-releasing hormone (TRH) neuron in the hypothalamic paraventricular nucleus (PVN) in thyroid axis regulation. In addition to their negative feedback action on TRH neurons in the hypothalamus, intrahypothalamic thyroid hormones can also modulate metabolism in adipose tissue and the liver via the autonomic nervous system. Congenital or acquired dysfunction of the hypothalamus or pituitary gland may result in central hypothyroidism (CeH). In the Netherlands, the prevalence of permanent congenital CeH as detected by neonatal screening is approximately 1 in 18000. In most neonates congenital CeH is accompanied by additional anterior pituitary hormone deficiencies, and many show clear morphological abnormalities such as a small anterior gland, a thin or absent pituitary stalk, or an ectopic posterior pituitary gland. Recently, a mutation in the immunoglobulin superfamily member 1 (IGSF1) gene was reported as a novel cause of X-linked, apparently isolated CeH occurring in neonates, children and adults. In adults, the most frequent cause of acquired CeH is a pituitary macroadenoma, usually accompanied by other pituitary hormone deficiencies. Central hyperthyroidism is a rare disorder, especially in children. In adults, it is mostly caused by a TSH-secreting pituitary adenoma. © 2014 Elsevier B.V. All rights reserved.

  16. Towards quantitative off-axis electron holographic mapping of the electric field around the tip of a sharp biased metallic needle

    DEFF Research Database (Denmark)

    Beleggia, Marco; Kasama, Takeshi; Larson, D. J.

    2014-01-01

    We apply off-axis electron holography and Lorentz microscopy in the transmission electron microscope to map the electric field generated by a sharp biased metallic tip. A combination of experimental data and modelling provides quantitative information about the potential and the field around the ...

  17. Next generation toroidal devices

    Energy Technology Data Exchange (ETDEWEB)

    Yoshikawa, Shoichi [Princeton Plasma Physics Lab., Princeton Univ., NJ (United States)

    1998-10-01

    A general survey of the possible approach for the next generation toroidal devices was made. Either surprisingly or obviously (depending on one`s view), the technical constraints along with the scientific considerations lead to a fairly limited set of systems for the most favorable approach for the next generation devices. Specifically if the magnetic field strength of 5 T or above is to be created by superconducting coils, it imposes minimum in the aspect ratio for the tokamak which is slightly higher than contemplated now for ITER design. The similar technical constraints make the minimum linear size of a stellarator large. Scientifically, it is indicated that a tokamak of 1.5 times in the linear dimension should be able to produce economically, especially if a hybrid reactor is allowed. For the next stellarator, it is strongly suggested that some kind of helical axis is necessary both for the (almost) absolute confinement of high energy particles and high stability and equilibrium beta limits. The author still favors a heliac most. Although it may not have been clearly stated in the main text, the stability afforded by the shearless layer may be exploited fully in a stellarator. (author)

  18. Jet maximization, axis minimization, and stable cone finding

    Science.gov (United States)

    Thaler, Jesse

    2015-10-01

    Jet finding is a type of optimization problem, where hadrons from a high-energy collision event are grouped into jets based on a clustering criterion. As three interesting examples, one can form a jet cluster that (i) optimizes the overall jet four-vector, (ii) optimizes the jet axis, or (iii) aligns the jet axis with the jet four-vector. In this paper, we show that these three approaches to jet finding, despite being philosophically quite different, can be regarded as descendants of a mother optimization problem. For the special case of finding a single cone jet of fixed opening angle, the three approaches are genuinely identical when defined appropriately, and the result is a stable cone jet with the largest value of a quantity J . This relationship is only approximate for cone jets in the rapidity-azimuth plane, as used at the Large Hadron Collider, though the differences are mild for small radius jets.

  19. Symmetry axis based object recognition under translation, rotation and scaling.

    Science.gov (United States)

    Hyder, Mashud; Islam, Md Monirul; Akhand, M A H; Murase, Kazuyuki

    2009-02-01

    This paper presents a new approach, known as symmetry axis based feature extraction and recognition (SAFER), for recognizing objects under translation, rotation and scaling. Unlike most previous invariant object recognition (IOR) systems, SAFER puts emphasis on both simplicity and accuracy of the recognition system. To achieve simplicity, it uses simple formulae for extracting invariant features from an object. The scheme used in feature extraction is based on the axis of symmetry and angles of concentric circles drawn around the object. SAFER divides the extracted features into a number of groups based on their similarity. To improve the recognition performance, SAFER uses a number of neural networks (NNs) instead of single NN are used for training and recognition of extracted features. The new approach, SAFER, has been tested on two of real world problems i.e., English characters with two different fonts and images of different shapes. The experimental results show that SAFER can produce good recognition performance in comparison with other algorithms.

  20. APS-U LATTICE DESIGN FOR OFF-AXIS ACCUMULATION

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Yipeng; Borland, M.; Lindberg, R.; Sajaev, V.

    2017-06-25

    A 67-pm hybrid-seven-bend achromat (H7BA) lattice is being proposed for a future Advanced Photon Source (APS) multi-bend-achromat (MBA) upgrade project. This lattice design pushes for smaller emittance and requires use of a swap-out (on-axis) injection scheme due to limited dynamic acceptance. Alternate lattice design work has also been performed for the APS upgrade to achieve better beam dynamics performance than the nominal APS MBA lattice, in order to allow off-axis accumulation. Two such alternate H7BA lattice designs, which target a still-low emittance of 90 pm, are discussed in detail in this paper. Although the single-particle-dynamics performance is good, simulations of collective effects indicate that surprising difficulty would be expected accumulating high single-bunch charge in this lattice. The brightness of the 90-pm lattice is also a factor of two lower than the 67-pm H7BA lattice.

  1. Electrostatic levitation under the single-axis feedback control condition

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    An electrostatic levitator with a single-axis feedback control system was developed on the basis of electric field analysis and optimum design for levitation electrodes. In order to realize the stable levitation of various types of materials such as metals, inorganic materials and polymers, we made both experimental and theoretical investigations to solve the four key problems of electric field optimization, sample position detecting, sample charging control and levitation voltage minimization. Under the capacitive induction charging condition, a sample with the size of 2.6–4.5 mm usually bears positive charges amounting to 10-9 Coulomb. Because the single-axis feedback control system responds quickly, it takes the levitated sample only 0.1 s from leaving the bottom electrode until attaining a stable levitation in the upright direction. The levitated sample displays satisfactory levitation stability in both the upright and the horizontal directions owing to the constraining force produced by spherical electrodes.

  2. Effects of structure flexibility on horizontal axis wind turbine performances

    Science.gov (United States)

    Coiro, D. P.; Daniele, E.; Scherillo, F.

    2013-10-01

    This work illustrates the effects of flexibility of rotor blades and turbine tower on the performances of an horizontal axis wind turbine (HAWT) designed by our ADAG research group, by means of several example applied on a recent project for a active pitch controlled upwind 60 kW HAWT. The influence of structural flexibility for blade only, tower only and blade coupled with tower configuration is investigated using an aero-elastic computer-aided engineering (CAE) tool for horizontal axis wind turbines named FAST developed at National Renewable Energy Laboratory (NREL) of USA. For unsteady inflow conditions in front of the isolated HAWT the performances in rigid and flexible operation mode are computed and compared in order to illustrate the limitation included within a classical rigid body approach to wind turbine simulation.

  3. Locating an axis-parallel rectangle on a Manhattan plane

    DEFF Research Database (Denmark)

    Brimberg, Jack; Juel, Henrik; Körner, Mark-Christoph

    2014-01-01

    In this paper we consider the problem of locating an axis-parallel rectangle in the plane such that the sum of distances between the rectangle and a finite point set is minimized, where the distance is measured by the Manhattan norm 1. In this way we solve an extension of the Weber problem to ext...... to extensive facility location. As......In this paper we consider the problem of locating an axis-parallel rectangle in the plane such that the sum of distances between the rectangle and a finite point set is minimized, where the distance is measured by the Manhattan norm 1. In this way we solve an extension of the Weber problem...

  4. Psychiatric Axis I Comorbidities among Patients with Gender Dysphoria

    Directory of Open Access Journals (Sweden)

    Azadeh Mazaheri Meybodi

    2014-01-01

    Full Text Available Objectives. Cooccurring psychiatric disorders influence the outcome and prognosis of gender dysphoria. The aim of this study is to assess psychiatric comorbidities in a group of patients. Methods. Eighty-three patients requesting sex reassignment surgery (SRS were recruited and assessed through the Persian Structured Clinical Interview for DSM-IV Axis I disorders (SCID-I. Results. Fifty-seven (62.7% patients had at least one psychiatric comorbidity. Major depressive disorder (33.7%, specific phobia (20.5%, and adjustment disorder (15.7% were the three most prevalent disorders. Conclusion. Consistent with most earlier researches, the majority of patients with gender dysphoria had psychiatric Axis I comorbidity.

  5. Tuning the DARHT Axis-II linear induction accelerator focusing

    Energy Technology Data Exchange (ETDEWEB)

    Ekdahl, Carl A. [Los Alamos National Laboratory

    2012-04-24

    Flash radiography of large hydrodynamic experiments driven by high explosives is a well-known diagnostic technique in use at many laboratories, and the Dual-Axis Radiography for Hydrodynamic Testing (DARHT) facility at Los Alamos produces flash radiographs of large hydrodynamic experiments. Two linear induction accelerators (LIAs) make the bremsstrahlung radiographic source spots for orthogonal views of each test. The 2-kA, 20-MeV Axis-I LIA creates a single 60-ns radiography pulse. The 1.7-kA, 16.5-MeV Axis-II LIA creates up to four radiography pulses by kicking them out of a longer pulse that has a 1.6-{mu}s flattop. The Axis-II injector, LIA, kicker, and downstream transport (DST) to the bremsstrahlung converter are described. Adjusting the magnetic focusing and steering elements to optimize the electron-beam transport through an LIA is often called 'tuning.' As in all high-current LIAs, the focusing field is designed to be as close to that of the ideal continuous solenoid as physically possible. In ideal continuous solenoidal transport a smoothly varying beam size can easily be found for which radial forces balance, and the beam is said to be 'matched' to the focusing field. A 'mismatched' beam exhibits unwanted oscillations in size, which are a source of free energy that contributes to emittance growth. This is undesirable, because in the absence of beam-target effects, the radiographic spot size is proportional to the emittance. Tuning the Axis-II LIA is done in two steps. First, the solenoidal focusing elements are set to values designed to provide a matched beam with little or no envelope oscillations, and little or no beam-breakup (BBU) instability growth. Then, steering elements are adjusted to minimize the motion of the centroid of a well-centered beam at the LIA exit. This article only describes the design of the tune for the focusing solenoids. The DARHT Axis-II LIA was required to be re-tuned after installing an

  6. Off-Axis Nulling Transfer Function Measurement: A First Assessment

    Science.gov (United States)

    Vedova, G. Dalla; Menut, J.-L.; Millour, F.; Petrov, R.; Cassaing, F.; Danchi, W. C.; Jacquinod, S.; Lhome, E.; Lopez, B.; Lozi, J.; hide

    2013-01-01

    We want to study a polychromatic inverse problem method with nulling interferometers to obtain information on the structures of the exozodiacal light. For this reason, during the first semester of 2013, thanks to the support of the consortium PERSEE, we launched a campaign of laboratory measurements with the nulling interferometric test bench PERSEE, operating with 9 spectral channels between J and K bands. Our objective is to characterise the transfer function, i.e. the map of the null as a function of wavelength for an off-axis source, the null being optimised on the central source or on the source photocenter. We were able to reach on-axis null depths better than 10(exp -4). This work is part of a broader project aiming at creating a simulator of a nulling interferometer in which typical noises of a real instrument are introduced. We present here our first results.

  7. Development of the adrenal axis in the neonatal rat

    Energy Technology Data Exchange (ETDEWEB)

    Guillet, Ronnie [Univ. of Rochester, NY (United States)

    1977-01-01

    Plasma corticosterone and ACTH concentrations were determined in neonatal rats 1, 7, 14, and 21 days old, under a variety of experimental conditions, to obtain more information on the postnatal development of the rat hypothalamo-adrenal (HHA) axis. The results indicate that: (1) there is a diminution followed by an increase in responsiveness of the adrenal gland, but the pituitary response to direct hormonal stimulation is unchanged during the first three postnatal weeks; (2) continued stimulation of the adrenal by ACTH or of the central nervous system (CNS) or hypothalamus by corticosterone is necessary during early postnatal development to allow normal maturation of the HHA axis; and (3) feedback inhibition is operative by birth, at least to a moderate degree. Taken together, the studies suggest that both the adrenal and pituitary glands are potentially functional at birth, but that the hypothalamic and CNS mediators of the stress response are not mature until at least the second or third postnatal week. (ERB)

  8. Shape and Spin Axis Model for 53 Kalypso

    Science.gov (United States)

    Franco, Lorenzo; Pilcher, Frederick; Pray, Donald P.; Maurice, Andejean

    2016-07-01

    We present shape and spin axis model for main-belt asteroid 53 Kalypso. The model was achieved with the lightcurve inversion process, using combined dense photometric data acquired from six apparitions between 1979-2012 and sparse data from USNO Flagstaff. Analysis of the resulting data found a sidereal period P = 9.035058 ± 0.000008 hours and two mirrored pole solutions at (168°, 12°) and (349°, 8°), with an error of ± 5 degrees.

  9. Spin Squeezing of One-Axis Twisting Model

    Science.gov (United States)

    Li, Song-Song

    2017-09-01

    We investigate spin squeezing of the one-axis twisting model. By using short-time approximation solutions of the angular momentum operators, we analytically and numerically calculate the spin squeezing parameter. It is shown that smaller linear interaction can produce a stronger spin squeezing and maintain a longer time interval. It is also shown that the stronger spin squeezing can be achieved by increasing the number of particles.

  10. Intestinal barrier function and the brain-gut axis.

    Science.gov (United States)

    Alonso, Carmen; Vicario, María; Pigrau, Marc; Lobo, Beatriz; Santos, Javier

    2014-01-01

    The luminal-mucosal interface of the intestinal tract is the first relevant location where microorganism-derived antigens and all other potentially immunogenic particles face the scrutiny of the powerful mammalian immune system. Upon regular functioning conditions, the intestinal barrier is able to effectively prevent most environmental and external antigens to interact openly with the numerous and versatile elements that compose the mucosal-associated immune system. This evolutionary super system is capable of processing an astonishing amount of antigens and non-immunogenic particles, approximately 100 tons in one individual lifetime, only considering food-derived components. Most important, to develop oral tolerance and proper active immune responses needed to prevent disease and inflammation, this giant immunogenic load has to be managed in a way that physiological inflammatory balance is constantly preserved. Adequate functioning of the intestinal barrier involves local and distant regulatory networks integrating the so-called brain-gut axis. Along this complex axis both brain and gut structures participate in the processing and execution of response signals to external and internal changes coming from the digestive tract, using multidirectional pathways to communicate. Dysfunction of brain-gut axis facilitates malfunctioning of the intestinal barrier, and vice versa, increasing the risk of uncontrolled immunological reactions that may trigger mucosal and brain low-grade inflammation, a putative first step to the initiation of more permanent gut disorders. In this chapter, we describe the structure, function and interactions of intestinal barrier, microbiota and brain-gut axis in both healthy and pathological conditions.

  11. Three-Axis Motion Compensated Crane Head Control

    OpenAIRE

    Henriksen, Vegard Wie; Røine, Audun Gerhardsen

    2016-01-01

    Offshore operations can be harsh and demanding and set personnel and equipment at risk. Ships will be exposed to the environmental forces of wind, waves and current, which will influence offshore crane operations considerably. This thesis addresses the use of a crane head, a Three Axis Compensator (TAC), constructed as a Delta parallel robot, to compensate for the motions of the ship in three axes. This type of robot has a rigid and accurate structure, and because of its highly nonlinear natu...

  12. Semiactive Vibration Control for Horizontal Axis Washing Machine

    Directory of Open Access Journals (Sweden)

    Barış Can Yalçın

    2015-01-01

    Full Text Available A semiactive vibration control method is developed to cope with the dynamic stability problem of a horizontal axis washing machine. This method is based on adjusting the maximum force values produced by the semiactive suspension elements considering a washing machine’s vibration data (three axis angular position and three axis angular acceleration values in time. Before actuation signals are received by the step motors of the friction dampers, vibration data are evaluated, and then, the step motors start to narrow or expand the radius of bracelets located on the dampers. This changes the damping properties of the damper in the suspension system, and thus, the semiactive suspension system absorbs unwanted vibrations and contributes to the dynamic stability of the washing machine. To evaluate the vibration data, the angular position and angular acceleration values in three axes are defined in a function, and the maximum forces produced by semiactive suspension elements are calculated according to the gradient of this function. The relation between the dynamic stability and the walking stability is also investigated. A motion (gyroscope and accelerometer sensor is installed on the top-front panel of the washing machine because a mathematical model of a horizontal axis washing machine suggests that the walking behavior starts around this location under some assumptions, and therefore, calculating the vibrations occurring there is crucial. Semiactive damping elements are located under the left and right sides of the tub. The proposed method is tested during the spinning cycle of washing machine operation, increasing gradually from 200 rpm to 900 rpm, which produces the most challenging vibration patterns for dynamic stability. Moreover, the sound power levels produced by the washing machine are measured to evaluate the noise performance of the washing machine while the semiactive suspension system is controlled. The effectiveness of the

  13. Spherical polarimetry on the three-axis spectrometer IN22

    Energy Technology Data Exchange (ETDEWEB)

    Regnault, L.P.; Geffray, B.; Fouilloux, P.; Longuet, B.; Mantegezza, F.; Tasset, F.; Lelievre-Berna, E.; Bourgeat-Lami, E.; Thomas, M.; Gibert, Y

    2003-07-01

    The existence at the ILL of three-axis spectrometers (TAS) offering high flux of polarized neutrons in the thermal range ('CRG' IN22 and IN20B) has open a new field of investigation of magnetic and lattice excitation spectra. In this paper, we will show recent technical developments concerning the installation and the optimization of the spherical neutron polarization analysis on TAS IN22.

  14. Gut-Brain Axis in Gastric Mucosal Damage and Protection

    Science.gov (United States)

    Sgambato, Dolores; Capuano, Annalisa; Sullo, Maria Giuseppa; Miranda, Agnese; Federico, Alessandro; Romano, Marco

    2016-01-01

    Abstract: Background The gut-brain axis plays a potential role in numerous physiological and pathological conditions. Several substances link stomach with central nervous system. In particular, hypothalamo-pituitary-adrenocortical axis, thyrotropin-releasing factor-containing nerve fibers and capsaicin-sensitive nerves are principal mediators of the harmful and protective central nervous system-mediated effects on gastric mucosa. Also, existing evidence indicates that nitric oxide, prostaglandins and calcitonin gene-related peptide play a role as final effectors of gastric protection. Methods We undertook a structured search of bibliographic databases for peer-reviewed research literature with the aim of focusing on the role of gut-brain axis in gastric damage and protection. In particular, we examined manuscripts dealing with the role of steroids, thyrotropin-releasing hormone, prostaglandins, melatonin, hydrogen sulfide and peptides influencing food intake (i.e. leptin, cholecystokinin, peptide YY, central glucagon–like peptide-1, and ghrelin). Also, the role of GABAergic and glutamatergic pathways in gastric mucosal protection have been examined. Results We found and reviewed 61 peer-reviewed papers dealing with the major aspects related to the role of gut brain axis in gastric mucosal damage and protection. Conclusions A dense neuronal network links stomach with central nervous system and a number of neurotransmitters and peptides functionally and anatomically related to central nervous system play a major role in contributing to gastric mucosal integrity. Exploiting the mechanisms underlying the connection between brain and gut may lead to a better understanding of the pathophysiology of gastric mucosal injury and to an improvement in the prevention and, eventually, management of gastric damage. PMID:26903151

  15. Plasma Transport at Magnetic Axis in Toroidal Confinement System

    Institute of Scientific and Technical Information of China (English)

    WANGZhongtian

    2001-01-01

    The particle orbits which intersect the magnetic axis behave differently from banana ones, referred to as potato orbits. The potential importance on tokamak transport is emphasized by Politzer, Lin, Tang, and Lee,and Shaing, Hazeltine, and Zarnstoff. However, there are many problems in the lasttwo papers. For example, the Eq. (48) in Ref. [5] should satisfy the orbit constraint which guarantees single value of the function go, that is, solubility condition, and Eq. (8) in Ref. [6] has the same problem.

  16. Super Earth Explorer: Coronagraphic Off-Axis Space Telescope

    CERN Document Server

    Schneider, J; Mawet, D; Baudoz, P; Beuzit, J L; Doyon, R; Marley, M; Stam, D; Tinetti, G; Traub, W; Trauger, J; Aylward, A; Cho, J Y K; Keller, C U; Udry, S

    2008-01-01

    The Super-Earth Explorer is an Off-Axis Space Telescope (SEE-COAST) designed for high contrast imaging. Its scientific objective is to make the physico-chemical characterization of exoplanets possibly down to 2 Earth radii >. For that purpose it will analyze the spectral and polarimetric properties of the parent starlight reflected by the planets, in the wavelength range 400-1250 nm

  17. Report Generator

    OpenAIRE

    2016-01-01

    Download data from HP Quality Center using of OTA Client. Implementation must be scalable to all projects under test. That is, it will be possible to generate automatically test reports at least for 2010, Modulaser and Gen2 (FW or SW). Report Generator is a software implemented in VBA that allows get data from HP Quality Center for export it (either tables, charts or text) to a document in Word format. Report Generator es un Software implementado en VBA que permite extraer datos de HP Q...

  18. The hypothalamic-pituitary-thyroid (HPT) axis in birds and its role in bird development and reproduction.

    Science.gov (United States)

    McNabb, F M Anne

    2007-01-01

    This article reviews thyroid function and its hypothalamic-pituitary-thyroid (HPT) axis control in birds with emphasis on the similarities and differences in thyroid function compared to mammals and other vertebrate classes. Thyroid hormones are important in metabolism and the thermogenesis required for homeothermy in birds, as in mammals, the other homeothermic class of vertebrates. Thyroid hormones play important roles in development and growth in birds, as is the case for all vertebrate classes. The developmental effects of thyroid hormones in birds are presented in the context of differences in precocial and altricial patterns of development and growth with emphasis on oviparous development. The sections on thyroid hormone actions include discussion of effects on the development of a number of tissue types as well as on seasonal organismal processes and interactions of the thyroid axis with reproduction. The current picture of how environmental chemicals may disrupt avian thyroid function is relatively limited and is presented in the context of the assessment endpoints that have been used to date. These endpoints are categorized as thyroid and HPT axis endpoints versus target organ endpoints. The final section discusses two recommended assay protocols, the avian two-generation toxicity assay and the avian one-generation assay, and whether these protocols can evaluate thyroid disruption in birds.

  19. Field programmable gate array–based servo control integrated chip for a six-axis articulated robot manipulator

    Directory of Open Access Journals (Sweden)

    Ying-Shieh Kung

    2016-05-01

    Full Text Available The objective of this article is to build a field programmable gate array–based six-axis servo control integrated chip which can integrate the function of a motion trajectory planning and the function of six position/speed/current servo controllers into one integrated chip. In the work, first, a mathematical modeling of a robot manipulator with the actuator using permanent magnet synchronous motor is derived. Second, the proportional controller in the position loop, a proportional–integral controller in the speed loop and a vector controller in the current loop for each axis are applied. Third, a system on a programmable chip technology which comprises an Altera field programmable gate array chip and an embedded soft-core Nios-II processor is considered to develop the proposed servo control integrated chip. However, in the servo control integrated chip, it has two modules. The first module is an embedded soft-core Nios-II processor which is used to generate the motion trajectory planning by software. The second module presents a six-axis servo controller intellectual property by hardware which is applied to execute six position/speed/current controllers. Therefore, the function of a motion trajectory command and the function of six position/speed/current servo controllers for a six-axis robot manipulator can be integrated into one field programmable gate array. Finally, to verify the effectiveness and correctness of the proposed field programmable gate array–based servo control integrated chip, a six-axis robot manipulator is applied and some experimental results are demonstrated.

  20. MARRT: Medial Axis biased rapidly-exploring random trees

    KAUST Repository

    Denny, Jory

    2014-05-01

    © 2014 IEEE. Motion planning is a difficult and widely studied problem in robotics. Current research aims not only to find feasible paths, but to ensure paths have certain properties, e.g., shortest or safest paths. This is difficult for current state-of-the-art sampling-based techniques as they typically focus on simply finding any path. Despite this difficulty, sampling-based techniques have shown great success in planning for a wide range of applications. Among such planners, Rapidly-Exploring Random Trees (RRTs) search the planning space by biasing exploration toward unexplored regions. This paper introduces a novel RRT variant, Medial Axis RRT (MARRT), which biases tree exploration to the medial axis of free space by pushing all configurations from expansion steps towards the medial axis. We prove that this biasing increases the tree\\'s clearance from obstacles. Improving obstacle clearance is useful where path safety is important, e.g., path planning for robots performing tasks in close proximity to the elderly. Finally, we experimentally analyze MARRT, emphasizing its ability to effectively map difficult passages while increasing obstacle clearance, and compare it to contemporary RRT techniques.

  1. Vasoactive intestinal peptide signaling axis in human leukemia

    Institute of Scientific and Technical Information of China (English)

    Glenn; Paul; Dorsam; Keith; Benton; Jarrett; Failing; Sandeep; Batra

    2011-01-01

    The vasoactive intestinal peptide (VIP) signaling axis constitutes a master "communication coordinator" between cells of the nervous and immune systems.To date,VIP and its two main receptors expressed in T lymphocytes,vasoactive intestinal peptide receptor (VPAC)1 and VPAC2,mediate critical cellular functions regulating adaptive immunity,including arresting CD4 T cells in G 1 of the cell cycle,protection from apoptosis and a potent chemotactic recruiter of T cells to the mucosa associated lymphoid compartment of the gastrointestinal tissues.Since the discovery of VIP in 1970,followed by the cloning of VPAC1 and VPAC2 in the early 1990s,this signaling axis has been associated with common human cancers,including leukemia.This review highlights the present day knowledge of the VIP ligand and its receptor expression profile in T cell leukemia and cell lines.Also,there will be a discussion describing how the anti-leukemic DNA binding transcription factor,Ikaros,regulates VIP receptor expression in primary human CD4 T lymphocytes and T cell lymphoblastic cell lines (e.g.Hut-78).Lastly,future goals will be mentioned that are expected to uncover the role of how the VIP signaling axis contributes to human leukemogenesis,and to establish whether the VIP receptor signature expressed by leukemic blasts can provide therapeutic and/or diagnostic information.

  2. A New, Adaptable, Optical High-Resolution 3-Axis Sensor

    Directory of Open Access Journals (Sweden)

    Niels Buchhold

    2017-01-01

    Full Text Available This article presents a new optical, multi-functional, high-resolution 3-axis sensor which serves to navigate and can, for example, replace standard joysticks in medical devices such as electric wheelchairs, surgical robots or medical diagnosis devices. A light source, e.g., a laser diode, is affixed to a movable axis and projects a random geometric shape on an image sensor (CMOS or CCD. The downstream microcontroller’s software identifies the geometric shape’s center, distortion and size, and then calculates x, y, and z coordinates, which can be processed in attached devices. Depending on the image sensor in use (e.g., 6.41 megapixels, the 3-axis sensor features a resolution of 1544 digits from right to left and 1038 digits up and down. Through interpolation, these values rise by a factor of 100. A unique feature is the exact reproducibility (deflection to coordinates and its precise ability to return to its neutral position. Moreover, optical signal processing provides a high level of protection against electromagnetic and radio frequency interference. The sensor is adaptive and adjustable to fit a user’s range of motion (stroke and force. This recommendation aims to optimize sensor systems such as joysticks in medical devices in terms of safety, ease of use, and adaptability.

  3. A Dual-Axis Electrostatically Driven MEMS Microgripper

    Directory of Open Access Journals (Sweden)

    Yukun Jia

    2014-11-01

    Full Text Available This paper presents the design of a new monolithic two- axis electrostatically actuated MEMS microgripper with integrated capacitive position and force sensors working at the micro-scale level. Each of the two jaws of the micro‐ gripper possesses two degrees-of-freedom (DOF and is capable of positioning in both x-and y-axes. Unlike existing works, where one gripper arm is actuated and other one is sensed, both arms of the proposed microgripper are actuated and sensed independently. A sensing scheme is constructed to provide the position and force signals in the noncontact and contact phases, respectively. By applying a 120V driving voltage, the jaw can provide 70 μm x-axis and 18 μm y-axis displacements with the force of 190 μN. By this design, the real-time position and grasping force information can be obtained in the dual sensing mode. Both analytical calculation and finite-element analysis (FEA were performed to verify the performance of the proposed design. A scaled-up prototype is designed, fabricated and tested through the experiment to verify the structure design of the microgripper.

  4. Blade pitch optimization methods for vertical-axis wind turbines

    Science.gov (United States)

    Kozak, Peter

    Vertical-axis wind turbines (VAWTs) offer an inherently simpler design than horizontal-axis machines, while their lower blade speed mitigates safety and noise concerns, potentially allowing for installation closer to populated and ecologically sensitive areas. While VAWTs do offer significant operational advantages, development has been hampered by the difficulty of modeling the aerodynamics involved, further complicated by their rotating geometry. This thesis presents results from a simulation of a baseline VAWT computed using Star-CCM+, a commercial finite-volume (FVM) code. VAWT aerodynamics are shown to be dominated at low tip-speed ratios by dynamic stall phenomena and at high tip-speed ratios by wake-blade interactions. Several optimization techniques have been developed for the adjustment of blade pitch based on finite-volume simulations and streamtube models. The effectiveness of the optimization procedure is evaluated and the basic architecture for a feedback control system is proposed. Implementation of variable blade pitch is shown to increase a baseline turbine's power output between 40%-100%, depending on the optimization technique, improving the turbine's competitiveness when compared with a commercially-available horizontal-axis turbine.

  5. A Two-Axis Goniometric Sensor for Tracking Finger Motion.

    Science.gov (United States)

    Wang, Lefan; Meydan, Turgut; Williams, Paul Ieuan

    2017-04-05

    The study of finger kinematics has developed into an important research area. Various hand tracking systems are currently available; however, they all have limited functionality. Generally, the most commonly adopted sensors are limited to measurements with one degree of freedom, i.e., flexion/extension of fingers. More advanced measurements including finger abduction, adduction, and circumduction are much more difficult to achieve. To overcome these limitations, we propose a two-axis 3D printed optical sensor with a compact configuration for tracking finger motion. Based on Malus' law, this sensor detects the angular changes by analyzing the attenuation of light transmitted through polarizing film. The sensor consists of two orthogonal axes each containing two pathways. The two readings from each axis are fused using a weighted average approach, enabling a measurement range up to 180 ∘ and an improvement in sensitivity. The sensor demonstrates high accuracy (±0.3 ∘ ), high repeatability, and low hysteresis error. Attaching the sensor to the index finger's metacarpophalangeal joint, real-time movements consisting of flexion/extension, abduction/adduction and circumduction have been successfully recorded. The proposed two-axis sensor has demonstrated its capability for measuring finger movements with two degrees of freedom and can be potentially used to monitor other types of body motion.

  6. A New, Adaptable, Optical High-Resolution 3-Axis Sensor.

    Science.gov (United States)

    Buchhold, Niels; Baumgartner, Christian

    2017-01-27

    This article presents a new optical, multi-functional, high-resolution 3-axis sensor which serves to navigate and can, for example, replace standard joysticks in medical devices such as electric wheelchairs, surgical robots or medical diagnosis devices. A light source, e.g., a laser diode, is affixed to a movable axis and projects a random geometric shape on an image sensor (CMOS or CCD). The downstream microcontroller's software identifies the geometric shape's center, distortion and size, and then calculates x, y, and z coordinates, which can be processed in attached devices. Depending on the image sensor in use (e.g., 6.41 megapixels), the 3-axis sensor features a resolution of 1544 digits from right to left and 1038 digits up and down. Through interpolation, these values rise by a factor of 100. A unique feature is the exact reproducibility (deflection to coordinates) and its precise ability to return to its neutral position. Moreover, optical signal processing provides a high level of protection against electromagnetic and radio frequency interference. The sensor is adaptive and adjustable to fit a user's range of motion (stroke and force). This recommendation aims to optimize sensor systems such as joysticks in medical devices in terms of safety, ease of use, and adaptability.

  7. A New, Adaptable, Optical High-Resolution 3-Axis Sensor

    Science.gov (United States)

    Buchhold, Niels; Baumgartner, Christian

    2017-01-01

    This article presents a new optical, multi-functional, high-resolution 3-axis sensor which serves to navigate and can, for example, replace standard joysticks in medical devices such as electric wheelchairs, surgical robots or medical diagnosis devices. A light source, e.g., a laser diode, is affixed to a movable axis and projects a random geometric shape on an image sensor (CMOS or CCD). The downstream microcontroller’s software identifies the geometric shape’s center, distortion and size, and then calculates x, y, and z coordinates, which can be processed in attached devices. Depending on the image sensor in use (e.g., 6.41 megapixels), the 3-axis sensor features a resolution of 1544 digits from right to left and 1038 digits up and down. Through interpolation, these values rise by a factor of 100. A unique feature is the exact reproducibility (deflection to coordinates) and its precise ability to return to its neutral position. Moreover, optical signal processing provides a high level of protection against electromagnetic and radio frequency interference. The sensor is adaptive and adjustable to fit a user’s range of motion (stroke and force). This recommendation aims to optimize sensor systems such as joysticks in medical devices in terms of safety, ease of use, and adaptability. PMID:28134824

  8. Glycation & the RAGE axis: targeting signal transduction through DIAPH1.

    Science.gov (United States)

    Shekhtman, Alexander; Ramasamy, Ravichandran; Schmidt, Ann Marie

    2017-02-01

    The consequences of chronic disease are vast and unremitting; hence, understanding the pathogenic mechanisms mediating such disorders holds promise to identify therapeutics and diminish the consequences. The ligands of the receptor for advanced glycation end products (RAGE) accumulate in chronic diseases, particularly those characterized by inflammation and metabolic dysfunction. Although first discovered and reported as a receptor for advanced glycation end products (AGEs), the expansion of the repertoire of RAGE ligands implicates the receptor in diverse milieus, such as autoimmunity, chronic inflammation, obesity, diabetes, and neurodegeneration. Areas covered: This review summarizes current knowledge regarding the ligand families of RAGE and data from human subjects and animal models on the role of the RAGE axis in chronic diseases. The recent discovery that the cytoplasmic domain of RAGE binds to the formin homology 1 (FH1) domain, DIAPH1, and that this interaction is essential for RAGE ligand-stimulated signal transduction, is discussed. Finally, we review therapeutic opportunities targeting the RAGE axis as a means to mitigate chronic diseases. Expert commentary: With the aging of the population and the epidemic of cardiometabolic disease, therapeutic strategies to target molecular pathways that contribute to the sequelae of these chronic diseases are urgently needed. In this review, we propose that the ligand/RAGE axis and its signaling nexus is a key factor in the pathogenesis of chronic disease and that therapeutic interruption of this pathway may improve quality and duration of life.

  9. Noise estimation for off-axis electron holography

    Energy Technology Data Exchange (ETDEWEB)

    Röder, Falk, E-mail: Falk.Roeder@Triebenberg.de [Triebenberg Labor, Institut für Strukturphysik, Technische Universität Dresden, D-01062 Dresden (Germany); Lubk, Axel; Wolf, Daniel [Triebenberg Labor, Institut für Strukturphysik, Technische Universität Dresden, D-01062 Dresden (Germany); Niermann, Tore [Institut für Optik und Atomare Physik, Technische Universität Berlin, Straße des 17. Juni 135, 10623 Berlin (Germany)

    2014-09-15

    Off-axis electron holography provides access to the phase of the elastically scattered wave in a transmission electron microscope at scales ranging from several hundreds of nanometres down to 0.1 nm. In many cases the reconstructed phase shift is directly proportional to projected electric and magnetic potentials rendering electron holography a useful and established characterisation method for materials science. However, quantitative interpretation of experimental phase shifts requires quantitative knowledge about the noise, which has been previously established for some limiting cases only. Here, we present a general noise transfer formalism for off-axis electron holography allowing to compute the covariance (noise) of reconstructed amplitude and phase from characteristic detector functions and general properties of the reconstruction process. Experimentally, we verify the presented noise transfer formulas for two different cameras with and without objects within the errors given by the experimental noise determination. - Highlights: • We derive a general noise transfer for the off-axis holographic reconstruction. • Noise transfer formulas given by F. Lenz are included as a special case. • We estimate the covariance of a hologram using the noise spread function. • We experimentally verify the derived noise transfer formulas.

  10. CMB Maximum Temperature Asymmetry Axis: Alignment with Other Cosmic Asymmetries

    CERN Document Server

    Mariano, Antonio

    2012-01-01

    We use a global pixel based estimator to identify the axis of the residual Maximum Temperature Asymmetry (MTA) (after the dipole subtraction) of the WMAP 7 year Internal Linear Combination (ILC) CMB temperature sky map. The estimator is based on considering the temperature differences between opposite pixels in the sky at various angular resolutions (4 degrees-15 degrees and selecting the axis that maximizes this difference. We consider three large scale Healpix resolutions (N_{side}=16 (3.7 degrees), N_{side}=8 (7.3 degrees) and N_{side}=4 (14.7 degrees)). We compare the direction and magnitude of this asymmetry with three other cosmic asymmetry axes (\\alpha dipole, Dark Energy Dipole and Dark Flow) and find that the four asymmetry axes are abnormally close to each other. We compare the observed MTA axis with the corresponding MTA axes of 10^4 Gaussian isotropic simulated ILC maps (based on LCDM). The fraction of simulated ILC maps that reproduces the observed magnitude of the MTA asymmetry and alignment wit...

  11. Simulation Study on the Emittance Compensation of Off-axis Emitted Beam in RF Photoinjector

    CERN Document Server

    Huang, Rui-Xuan; Jia, Qi-Ka; Papadopoulos, Christos; Sannibale, Fernando

    2016-01-01

    To make full use of photocathode material and improve its quantum efficiency lifetime, it can be necessary to operate laser away from the cathode center in photoinjectors. In RF guns, the off-axis emitted beam will see a time-dependent RF effect, which would generate a significant growth in transverse emittance. It has been demonstrated that such an emittance growth can be almost completely compensated by orienting the beam on a proper orbit in the downstream RF cavities along the injector. In this paper we analyze in detail the simulation techniques used in reference[1] and the issues associated with them. The optimization of photoinjector systems involving off-axis beams is a challenging problem. To solve this problem, one needs advanced simulation tools including both genetic algorithms and an efficient algorithm for 3D space charge. In this paper, we report on simulation studies where the two codes ASTRA and IMPACT-T are used jointly to overcome these challenges, in order to optimize a system designed to ...

  12. H∞ controller design for a 4-meter direct-drive azimuth axis

    Science.gov (United States)

    Chen, Li-Yan; Zhang, Zhen-Chao; Song, Xiao-Li; Wang, Da-Xing

    2015-11-01

    To pursue a higher imaging resolution for exploring more details in the information conveyed by the Universe, the next generation of optical telescopes based on a direct drive widely employ the extremely large aperture structure, which also introduces more disturbances and uncertain factors to the control system. Facing this new challenge, the PID control method in main-axis control systems of traditional astronomical telescopes cannot suffice for the requirement of the tracking precision and disturbance sensitivity in angular velocity. To overcome this shortcoming, we establish a dynamic model and propose an H∞ controller for a 4-meter azimuth direct drive control system that consists of a revolving platform (azimuth axis), a three-phase torque motor, a motor drive, an encoder, a data acquisition card and a small computers. Simulations are carried out to analyze the model and guide the real experiments. Experimental results show that the proposed H∞ controller reduces the tracking error by a maximum of 80.69% (average 57.8%) and the disturbance sensitivity by a maximum of 82.3% (average 50.96%) compared with the traditional tuned PI controller; furthermore, the order of the model describing the proposed controller can be reduced to three, thus its feasibility in real systems is guaranteed.

  13. A comparison between the dynamics of horizontal and vertical axis offshore floating wind turbines.

    Science.gov (United States)

    Borg, M; Collu, M

    2015-02-28

    The need to further exploit offshore wind resources in deeper waters has led to a re-emerging interest in vertical axis wind turbines (VAWTs) for floating foundation applications. However, there has been little effort to systematically compare VAWTs to the more conventional horizontal axis wind turbine (HAWT). This article initiates this comparison based on prime principles, focusing on the turbine aerodynamic forces and their impact on the floating wind turbine static and dynamic responses. VAWTs generate substantially different aerodynamic forces on the support structure, in particular, a potentially lower inclining moment and a substantially higher torque than HAWTs. Considering the static stability requirements, the advantages of a lower inclining moment, a lower wind turbine mass and a lower centre of gravity are illustrated, all of which are exploitable to have a less costly support structure. Floating VAWTs experience increased motion in the frequency range surrounding the turbine [number of blades]×[rotational speed] frequency. For very large VAWTs with slower rotational speeds, this frequency range may significantly overlap with the range of wave excitation forces. Quantitative considerations are undertaken comparing the reference NREL 5 MW HAWT with the NOVA 5 MW VAWT.

  14. Reflective off-axis point-diffraction interferometer based on Michelson architecture

    Science.gov (United States)

    Bai, Hongyi; Guo, Lili; Zhong, Zhi; Shan, Mingguang; Zhang, Yabin

    2015-02-01

    A reflective off-axis point-diffraction interferometer based on Michelson architecture is built to measure static and dynamic quantitative phase in a single shot. The interferometer is constructed by a beam-splitter, a pinhole mirror, a reflective mirror and two lenses to build a 4f optical system. The pinhole mirror is used as a low-pass spatial filter to generate reference wave. By tilting the reflective mirror, a small angle is created between the object beam and the reference beam to enable an off-axis interferogram. To reconstruct an interferogram with a few fringes, Kreis Fourier method is used to recovery the specimen phase. Using a plano-convex cylinder lens and an evaporative alcohol drop as the specimens, experiments are run to verify the effectiveness and robustness with this interferometer. Experimental results show that this interferometer has not only simple setup and good anti-interference performance, but also good real-time ability, which makes it suitable for dynamic phase measurement.

  15. Emerging targets in cancer management: role of the CXCL12/CXCR4 axis

    Directory of Open Access Journals (Sweden)

    Cojoc M

    2013-09-01

    Full Text Available Monica Cojoc,1 Claudia Peitzsch,1 Franziska Trautmann,1 Leo Polishchuk,2 Gennady D Telegeev,2 Anna Dubrovska11OncoRay National Center for Radiation Research in Oncology, Medical Faculty Carl Gustav Carus, Dresden University of Technology, Dresden, Germany; 2Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, Kyiv, UkraineAbstract: The chemokine CXCL12 (SDF-1 and its cell surface receptor CXCR4 were first identified as regulators of lymphocyte trafficking to the bone marrow. Soon after, the CXCL12/CXCR4 axis was proposed to regulate the trafficking of breast cancer cells to sites of metastasis. More recently, it was established that CXCR4 plays a central role in cancer cell proliferation, invasion, and dissemination in the majority of malignant diseases. The stem cell concept of cancer has revolutionized the understanding of tumorigenesis and cancer treatment. A growing body of evidence indicates that a subset of cancer cells, referred to as cancer stem cells (CSCs, plays a critical role in tumor initiation, metastatic colonization, and resistance to therapy. Although the signals generated by the metastatic niche that regulate CSCs are not yet fully understood, accumulating evidence suggests a key role of the CXCL12/CXCR4 axis. In this review we focus on physiological functions of the CXCL12/CXCR4 signaling pathway and its role in cancer and CSCs, and we discuss the potential for targeting this pathway in cancer management.Keywords: epithelial-to-mesenchymal transition, cancer stem cells, metastasis

  16. Millimeter-Wave Phaseless Antenna Measurement Based on a Modified Off-Axis Holography Setup

    Science.gov (United States)

    Arboleya, Ana; Ala-Laurinaho, Juha; Laviada, Jaime; Álvarez, Yuri; Las-Heras, Fernando; Räisänen, Antti V.

    2016-02-01

    A novel scheme for planar near-field phaseless antenna measurement based on off-axis holography is presented. Separation of the image terms of the hologram is artificially increased by multiplexing the measurements of two sub-sampled holograms generated with two 180° phase-shifted reference waves. Combination of both sub-sampled holograms produces replicas of the image terms at half a period distance of the originals in the spectral domain, while the amplitude of the original image terms is highly reduced, easing the filtering process of the desired replica. The higher separation of the image terms reduces overlapping making the method suitable also for the characterization of medium and low gain antennas in the near-field. As the separation is artificially increased, the reference antenna can be placed close to the antenna under test allowing to reduce the scan distance and the sensitivity to scan axis errors. Nevertheless, spatial multiplexing requires the retrieved data to be spatially low-pass filtered to remove the effect of the aliasing. Mirror reflection is used for illuminating the acquisition plane with the reference wave, being the phase shift achieved by means of a mechanical displacement of the mirror. The effect of the location of the reference antenna on the position and shape of the image terms and their replicas has been studied through numerical simulations for a setup in the W-band. Experimental validation of the method is presented for the characterization of three different antennas at 94 GHz.

  17. Reciprocal regulation of Wnt and Gpr177/mouse Wntless is required for embryonic axis formation.

    Science.gov (United States)

    Fu, Jiang; Jiang, Ming; Mirando, Anthony J; Yu, Hsiao-Man Ivy; Hsu, Wei

    2009-11-03

    Members of the Wnt family are secreted glycoproteins that trigger cellular signals essential for proper development of organisms. Cellular signaling induced by Wnt proteins is involved in diverse developmental processes and human diseases. Previous studies have generated an enormous wealth of knowledge on the events in signal-receiving cells. However, relatively little is known about the making of Wnt in signal-producing cells. Here, we describe that Gpr177, the mouse orthologue of Drosophila Wls, is expressed during formation of embryonic axes. Embryos with deficient Gpr177 exhibit defects in establishment of the body axis, a phenotype highly reminiscent to the loss of Wnt3. Although many different mammalian Wnt proteins are required for a wide range of developmental processes, the Wnt3 ablation exhibits the earliest developmental abnormality. This suggests that the Gpr177-mediated Wnt production cannot be substituted. As a direct target of Wnt, Gpr177 is activated by beta-catenin and LEF/TCF-dependent transcription. This activation alters the cellular distributions of Gpr177 which binds to Wnt proteins and assists their sorting and secretion in a feedback regulatory mechanism. Our findings demonstrate that the loss of Gpr177 affects Wnt production in the signal-producing cells, leading to alterations of Wnt signaling in the signal-receiving cells. A reciprocal regulation of Wnt and Gpr177 is essential for the patterning of the anterior-posterior axis during mammalian development.

  18. Digital Hardware Realization of Forward and Inverse Kinematics for a Five-Axis Articulated Robot Arm

    Directory of Open Access Journals (Sweden)

    Bui Thi Hai Linh

    2015-01-01

    Full Text Available When robot arm performs a motion control, it needs to calculate a complicated algorithm of forward and inverse kinematics which consumes much CPU time and certainty slows down the motion speed of robot arm. Therefore, to solve this issue, the development of a hardware realization of forward and inverse kinematics for an articulated robot arm is investigated. In this paper, the formulation of the forward and inverse kinematics for a five-axis articulated robot arm is derived firstly. Then, the computations algorithm and its hardware implementation are described. Further, very high speed integrated circuits hardware description language (VHDL is applied to describe the overall hardware behavior of forward and inverse kinematics. Additionally, finite state machine (FSM is applied for reducing the hardware resource usage. Finally, for verifying the correctness of forward and inverse kinematics for the five-axis articulated robot arm, a cosimulation work is constructed by ModelSim and Simulink. The hardware of the forward and inverse kinematics is run by ModelSim and a test bench which generates stimulus to ModelSim and displays the output response is taken in Simulink. Under this design, the forward and inverse kinematics algorithms can be completed within one microsecond.

  19. Computer aided classification of cell nuclei in the gastrointestinal tract by volume and principal axis

    Science.gov (United States)

    Sagstetter, Ann M.; Camp, Jon J.; Lurken, Matthew S.; Szurszewski, Joseph H.; Farrugia, Gianrico; Gibbons, Simon J.; Robb, Richard A.

    2007-03-01

    Normal function of the gastrointestinal tract involves the coordinated activity of several cell types Human disorders of motor function of the gastrointestinal tract are often associated with changes in the number of these cells. For example, in diabetic patients, abnormalities in gastrointestinal transit are associated with changes in nerves and interstitial cells of Cajal (ICC), two key cells that generate and regulate motility. ICC are cells of mesenchymal origin that function as pacemakers and amplify neuronal signals in the gastrointestinal tract. Quantifying the changes in number of specific cell types in tissues from patients with motility disorders is challenging and requires immunolabeling for specific antigens. The shape of nuclei differs between the cell types in the wall of the gastrointestinal tract. Therefore the objective of this study was to determine whether cell nuclei can be classified by analyzing the 3D morphology of the nuclei. Furthermore, the orientation of the long axis of nuclei changes within and between the muscle layers. These features can be used to classify and differentially label the nuclei in confocal volume images of the tissue by computing the principal axis of the coordinates of the set of voxels forming each nucleus and thereby to identify cells by their nuclear morphology. Using this approach, we were able to separate and quantify nuclei in the smooth muscle layers of the tissue. Therefore we conclude that computer-aided classification of cell nuclei can be used to identify changes in the cell types expressed in gastrointestinal smooth muscle.

  20. Soft X-ray spectrometer design for warm dense plasma measurements on DARHT Axis-I

    Energy Technology Data Exchange (ETDEWEB)

    Ramey, Nicholas Bryan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Perry, John Oliver [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Coleman, Joshua Eugene [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-07-11

    A preliminary design study is being performed on a soft X-ray spectrometer to measure K-shell spectra emitted by a warm dense plasma generated on Axis-I of the Dual-Axis Radiographic Hydrodynamic Testing (DARHT) facility at Los Alamos National Laboratory. The 100-ns-long intense, relativistic electron pulse with a beam current of 1.7 kA and energy of 19.8 MeV deposits energy into a thin metal foil heating it to a warm dense plasma. The collisional ionization of the target by the electron beam produces an anisotropic angular distribution of K-shell radiation and a continuum of both scattered electrons and Bremsstrahlung up to the beam energy of 19.8 MeV. The principal goal of this project is to characterize these angular distributions to determine the optimal location to deploy the soft X-ray spectrometer. In addition, a proof-of-principle design will be presented. The ultimate goal of the spectrometer is to obtain measurements of the plasma temperature and density to benchmark equation-of-state models of the warm dense matter regime.

  1. Measurement of multiaxial ply strength by an off-axis flexure test

    Science.gov (United States)

    Crews, John H., Jr.; Naik, Rajiv A.

    1992-01-01

    An off-axis flexure (OAF) test was performed to measure ply strength under multiaxial stress states. This test involves unidirectional off-axis specimens loaded in bending, using an apparatus that allows these anisotropic specimens to twist as well as flex without the complications of a resisting torque. A 3D finite element stress analysis verified that simple beam theory could be used to compute the specimen bending stresses at failure. Unidirectional graphite/epoxy specimens with fiber angles ranging from 90 deg to 15 deg have combined normal and shear stresses on their failure planes that are typical of 45 deg plies in structural laminates. Tests for a range of stress states with AS4/3501-6 specimens showed that both normal and shear stresses on the failure plane influenced cracking resistance. This OAF test may prove to be useful for generating data needed to predict ply cracking in composite structures and may also provide an approach for studying fiber-matrix interface failures under stress states typical of structures.

  2. Aerodynamic Response of a Pitching Airfoil with Pulsed Circulation Control for Vertical Axis Wind Turbine Applications

    Science.gov (United States)

    Panther, Chad C.

    Vertical Axis Wind Turbines (VAWTs) have experienced a renewed interest in development for urban, remote, and offshore applications. Past research has shown that VAWTs cannot compete with Horizontals Axis Wind Turbines (HAWTs) in terms of energy capture efficiency. VAWT performance is plagued by dynamic stall (DS) effects at low tip-speed ratios (lambda), where each blade pitches beyond static stall multiple times per revolution. Furthermore, for lambdasize and strength of wake vorticity during DS, resulting in lower profile drag relative to baseline and steady actuation cases. A database of pitching airfoil test data, including overshoot and hysteresis of aerodynamic coefficients (Cl, Cd), was compiled for improved analytical model inputs to update CCVAWT performance predictions, where the aforementioned L/D improvements will be directly reflected. Relative to a conventional VAWT with annual power output of 1 MW, previous work at WVU proved that the addition of steady jet CC could improve total output to 1.25 MW. However, the pumping cost to generate the continuous jet reduced yearly CCVAWT net gains to 1.15 MW. The current study has shown that pulsed CC jets can recover 4% of the pumping demands due to reduced mass flow requirements, increasing annual CCVAWT net power production to 1.19 MW, a 19% improvement relative to the conventional turbine.

  3. Structural evolution of the East Pacific Rise axis from 13°10'N to 10°35'N: interpretations from SeaMARC I data

    Science.gov (United States)

    Crane, Kathleen

    1987-05-01

    In 1983 the SeaMARC I and the Sea Beam systems imaged the East Pacific Rise (EPR) and the Clipperton Transform Fault from 13°10'N to 9°50'N revealing both magmatic and tectonic segmentation along the rise axis. Tectonic segments are defined by an undulating axial zone of extension which widens and narrows at an average wavelength of 45 km. In addition, axial fissure-fault-density and -length curves reveal wavelengths of 30 and 56 km. The narrowest axial zones, centers on the rise axis about which seamounts cluster. Superimposed on the intermediate-wavelength highs are smaller highs (from 10 to 50 km in length) which are truncated by overlapping spreading centers (OSC's) at their distal edges. The rise axis widens near OSC's while it narrows and disappears near the Clipperton Transform Fault suggesting that transforms and OSC's have different origins. Imagery on and adjacent to a few OSC's reveals that in some cases OSC's migrate along the axis forming relict off-axial structural traces at oblique angles (285°-330°) to the axis. Off-axial fault density and length curves have wavelengths similar to the axial curves. However, fault densities to the west of the axis are somewhat antisymmetric to fissure-fault densities on the axis. In contrast, faults to the east of the axis nearly mimic fissure-fault density and length curves on the axis suggesting that the fracture pattern is controlled by the state of deviatoric stress in the adjacent Cocos Plate to the east. The data suggest that large deep-seated magma diapirs may dominate the magmatic segmentation of the EPR generating dynamically supported 155 km wavelength highs. Smaller, shallower magma cupulas may rise as fingers to the seafloor above the large diapirs. Where the magma erupts may be a factor of the thin skin tectonic segmentation of the rise axis formed in response to the state of deviatoric stress in the upper crust. Small OCS's may form at crustal weak points and may migrate in response to magma body

  4. A vertical axis tracking method - theoretical consideration for photovoltaic systems at high latitude sites

    Energy Technology Data Exchange (ETDEWEB)

    Gupta, G. R. K; Narasimba Rao, A. V; Subramanyam S [Department of Mechanical Engineering, Warangal (India)

    2000-07-01

    In photovoltaic power generation the photovoltaic array is the most cost intensive unit. In order to make the photovoltaic power competitive the array is to be loaded to its maximum capacity for the longer periods of time. One of the strategies to minimize the cosine effect is by tracking the device. In this paper a novel method of Vertical Axis tracking system with optimum tilt is described. Optimum tilt is obtained by weighting the beam radiation with the altitude of the sun over day. Oslo is chosen for the study because the system is better suited for places having higher latitudes. It is observed that the energy collected in the vertical axis tracking is almost equivalent to that of two-axis tracking mode at latitudes 66.7axis tracking. [Spanish] En la generacion de energia electrica fotovoltaica el arreglo fotovoltaico es la unidad mas costosa. Para hacer la energia electrica fotovoltaica competitiva el arreglo debe de ser cargado a su maxima capacidad por periodos de tiempo mas largos. Una de las estrategias para minimizar el efecto del coseno es haciendo que el dispositivo siga la trayectoria. En este articulo se describe un metodo novedoso de un sistema de seguimiento de eje vertical con inclinacion optima. La inclinacion optima se obtiene contrapesando la radiacion del rayo contra la altitud del sol durante el dia. Se escogio la Ciudad de Oslo para el estudio porque el sistema es mas adecuado para lugares que tienen altas latitudes. Se observa que la energia recolectada en el seguidor de eje vertical es casi equivalente al modo de rastreo de dos ejes a latitudes de 6.7< {phi}< 23.45. Este metodo ofrece una construccion mecanica mas simple, el cambio del angulo de rastreo en un ano es de 32 grados Celsius que es inferior si se compara con los 47grados Celsius

  5. Endomorphins and activation of the hypothalamo-pituitary-adrenal axis.

    Science.gov (United States)

    Coventry, T L; Jessop, D S; Finn, D P; Crabb, M D; Kinoshita, H; Harbuz, M S

    2001-04-01

    Endomorphin (EM)-1 and EM-2 are opioid tetrapeptides recently located in the central nervous system and immune tissues with high selectivity and affinity for the mu-opioid receptor. Intracerebroventricular (i.c.v.) administration of morphine stimulates the hypothalamo-pituitary-adrenal (HPA) axis. The present study investigated the effect of centrally administered EM-1 and EM-2 on HPA axis activation. Rats received a single i.c.v. injection of either EM-1 (0.1, 1.0, 10 microg), EM-2 (10 microg), morphine (10 microg), or vehicle (0.9% saline). Blood samples for plasma corticosterone determinations were taken immediately prior to i.c.v. administration and at various time points up to 4 h post-injection. Trunk blood, brains and pituitaries were collected at 4 h. Intracerebroventricular morphine increased plasma corticosterone levels within 30 min, whereas EM-1 and EM-2 were without effect. In addition, pre-treatment of i.c.v. EM-1 did not block the rise in corticosterone after morphine. Corticotrophin-releasing factor (CRF) mRNA and arginine vasopressin (AVP) mRNA in the paraventricular nucleus (PVN) and POMC mRNA in the anterior pituitary were found to be unaffected by either morphine or endomorphins. Since release of other opioids are elevated in response to acute stress, we exposed rats to a range of stressors to determine whether plasma EM-1 and EM-2 can be stimulated by HPA axis activation. Plasma corticosterone, ACTH and beta-endorphin were elevated following acute restraint stress, but concentrations of plasma EM-1-immunoreactivity (ir) and EM-2-ir did not change significantly. Corticosterone, ACTH and beta-endorphin were further elevated in adjuvant-induced arthritis (AA) rats by a single injection of lipopolysaccharide (LPS), but not by restraint stress. In conclusion, neither EM-1 or EM-2 appear to influence the regulation of the HPA axis. These data suggest that endomorphins may be acting on a different subset of the mu-opioid receptor than morphine. The

  6. Drop Axis Ratio Distributions in Stratiform and Convective Rain

    Science.gov (United States)

    Thurai, M.; Bringi, V. N.; Petersen, W. A.; Schultz, C.

    2010-01-01

    A fully calibrated low profile 2D video disdrometer (2DVD) has been recording many different rainfall events in Northern Alabama (USA) since June 2007. An earlier publication reported drop shapes and axis ratio distributions determined for some of the events. For one of the cases examined, a noticeable shift in the 3.5 - 3.75 mm drop axis ratio distribution was noted. In this paper, we extend the earlier work by separating the 2DVD measurements into stratiform and convective rain. The separation is made possible by using the minute-by-minute drop size distribution (DSD) measured by the 2DVD. The 1-minute DSDs are fitted to a gamma distribution, and using a simple indexing technique which involves two of the fitted parameters, periods of convective and stratiform rain are separated for a given event. The output of the DSD indexing technique is qualitatively confirmed by comparing with simultaneous time series observations from a co-located UHF profiler which continuously records height profiles of reflectivity, Doppler mean and spectral width, all of which enable the identification of bright-band periods and, furthermore, periods of moderate and deep convection. Excellent consistency is found between the output of the DSD-based separation method and the profiler observations. Next, we utilize the output of DSD index-based separation method to flag the periods of severe convection for a given event. Drop axis ratios during the flagged periods are derived and compared with those during stratiform rain periods. Five cases have been considered. Axis ratio distributions do not show appreciable differences between stratiform and convective periods for four of the cases. The fifth case (the same case as reported earlier) shows a shift in the 3.5 - 3.75 mm drop axis ratios during a prolonged period of convection. The contoured shapes for these drops determined from the 2DVD camera data indicate the possibility of non-axisymmetric oscillations, compared with the contoured

  7. Near-resonant second-order nonlinear susceptibility in c-axis oriented ZnO nanorods

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Weiwei; Wang, Kai; Long, Hua; Wang, Bing, E-mail: wangbing@hust.edu.cn; Lu, Peixiang, E-mail: lupeixiang@hust.edu.cn [Wuhan National Laboratory for Optoelectronics and School of Physics, Huazhong University of Science and Technology, Wuhan 430074 (China); Chu, Sheng [School of Physics and Engineering, Sun Yat-Sen University, Guangzhou 510275 (China)

    2014-08-18

    Near-resonant second-harmonic generation (SHG) in c-axis oriented ZnO nanorods is studied under the femtosecond laser with wavelength from 780 nm to 810 nm. A highly efficient SHG is obtained, which is attributed to the d{sub 131} component of the second-order nonlinear susceptibility. The largest d{sub 131} value is estimated to be 10.2 pm/V at the pumping wavelength of 800 nm, which indicates a large SHG response of the c-axis oriented ZnO nanorods in the near-resonant region. Theoretical calculation based on finite-difference time-domain simulation suggests a four-fold local-field enhancement of the SHG.

  8. Feed drive modelling for the simulation of tool path tracking in multi-axis High Speed Machining

    CERN Document Server

    Prévost, David; Lartigue, Claire; Dumur, Didier

    2011-01-01

    Within the context of High Speed Machining, it is essential to manage the trajectory generation to achieve both high surface quality and high productivity. As feed drives are one part of the set Machine tool - Numerical Controller, it is necessary to improve their performances to optimize feed drive dynamics during trajectory follow up. Hence, this paper deals with the modelling of the feed drive in the case of multi axis machining. This model can be used for the simulation of axis dynamics and tool-path tracking to tune parameters and optimize new frameworks of command strategies. A procedure of identification based on modern NC capabilities is presented and applied to industrial HSM centres. Efficiency of this modelling is assessed by experimental verifications on various representative trajectories. After implementing a Generalized Predictive Control, reliable simulations are performed thanks to the model. These simulations can then be used to tune parameters of this new framework according to the tool-pat...

  9. Convection-Diffusion Model for Atmospheric Pressure Plasma Jets: Obtaining Off-Axis Data from On-Axis Measurements

    Science.gov (United States)

    Schmidt-Bleker, Ansgar; Dünnbier, Mario; Winter, Jörn; Weltmann, Klaus-Dieter; Reuter, Stephan

    2012-10-01

    An analytical convection-diffusion model for atmospheric pressure plasma jets is presented. The model can be applied both for ambient air species diffusion and for heat transfer into a jets effluent. Using on-axis data from experiments as input, the model can be used to extrapolate the measured quantities to the complete domain for laminar flows and near-axis region for turbulent flows. The method is applied to experimental data obtained from molecular beam mass spectrometry as well as from a VUV absorption spectrometry method using the plasma jet itself as a VUV emitter. The measurements are conducted on a turbulent atmospheric pressure argon plasma jet with a protective gas nozzle, allowing for the creation of a shielding gas curtain around the plasma jets effluent. The results obtained from the hybrid analytical-experimental method are compared to computational fluid dynamics simulations.

  10. Urban energy generation and the role of cities

    DEFF Research Database (Denmark)

    Groth, Niels Boje; Fertner, Christian; Große, Juliane

    2016-01-01

    on energy generation and distribution. However, contemporary focus on sustainable and efficient use of resources and energy at local level, mainstreaming of renewable energy production and ideas of urban energy harvesting put energy generation again on the local agenda. The role of cities can be twofold: (1......) cities as producers and (2) cities as enablers or promoters. Furthermore, energy production (renewable or not) has to happen somewhere, potentially also in the city where consumption takes place, and is related to specific spatial conditions. We review the contemporary options of urban energy generation......Although a major part of energy consumption happens in cities, contemporary energy generation is less obviously connected to the urban structure. Energy based on fossil fuels and consumed in transportation is produced at global scale; energy for electricity is usually distributed through a national...

  11. Towards Improved Thermoelectric Generator Materials

    Science.gov (United States)

    Julian Goldsmid, H.

    2017-05-01

    Over recent years, new thermoelectric materials have been developed with values for the dimensionless figure of merit, zT, substantially greater than unity. This has opened up the possibility of many new applications, particularly those involving the utilisation of waste heat. However, further improvements are necessary if thermoelectric generation is to have a significant impact on the world's energy problems. It is well known that zT for a single energy band can be related to the Fermi energy and a parameter ( μ/λ L) ( m*/m)3/2, where μ is the carrier mobility, m*/m is the ratio of the carrier effective mass to the mass of a free electron and λ L is the lattice thermal conductivity. However, even when this parameter tends towards infinity, zT does not become much greater than 1 unless the Fermi level lies within the energy gap, far from the appropriate band edge. Thus, the magnitude of the energy gap is becoming of increasing importance. The two-fold requirements of a high value of ( μ/λ L) ( m*/m)3/2 and a sufficiently large energy gap are discussed. It is also shown that the likelihood of the required conditions being met at elevated temperatures can be predicted from low-temperature observations. It is, of course, much more difficult to make accurate determinations of the thermoelectric properties at higher temperatures.

  12. Disector Z-axis mechanical method for stereology

    Directory of Open Access Journals (Sweden)

    Ricardo Xavier-Vidal

    2010-06-01

    Full Text Available The purpose of this work is to calibrate a not expensive microscope to be applied in Optical Disector estimation. The evaluation of "Z-axis" bias and the "Z-axis" calibration were made utilizing a cover slip and a "manual digimatic outside micrometer scale" (Mitutoyo, Japan. Calibrating the cover slip we performed the calibration of the "Z-axis" of a microscope. In the cover slip two lines were painted with different colors using a pen glass. A blue line was painted on the up surface and another line (red on the bottom surface of the cover slip forming a cross. Two metal rings with one palette welded in each were adapted in the microscope. Other palette was welded in the gross focuses in order to restrict the route of the fine focuses (Z-axis study using the two palettes fixed in both rings. Results show that 10 micrometers in "Z-axis" were equal to 3.2 micrometers in the scale of its fine focuses of the microscope. Then, a Disector of 10μm (10μm in Z-axis is equal to 3.2 micrometers in the fine focuses of this microscope. In conclusion, "Z-axis" calibration is crucial to assure enough precision for Disector Method since the equipment can be manufactured without the ideal precision or its precision can be lost after use.O propósito deste trabalho é a Calibração de um microscópio comum de baixo custo de forma a usá-lo para estimativas do Método Disector Óptico. A avaliação do viés e a calibração do "eixo-Z" foram feitas usando uma lamínula e um "micrômetro manual digital" (Mitutoyo, Japan. Com a cali-bração da lamínula, calibramos o "eixo-Z" de um microscópio. Foram pintadas duas linhas com diferentes cores utilizando canetas para vidro. Uma linha (azul foi pintada na superfície superior da lamínula e outra linha (vermelha foi pintada na superfície inferior da lamínula, formando uma cruz. Dois anéis de metal com uma paleta de metal soldada a cada um deles foram adaptados ao micrométrico do microscópio. Outra paleta foi

  13. Manufacturing progress of production of high aspherical axis and off-axis astronomical and space optics for the last decade

    Science.gov (United States)

    Semenov, Aleksandr P.; Abdulkadyrov, Magomed A.; Belousov, Sergey P.; Ignatov, Aleksandr N.; Patrikeev, Vladimir E.

    2016-10-01

    The article describes the technology of production of astronomical and space mirrors from Astrositall CO-115M including its properties and stability of these properties over time and presents the results of material long-term testing. The article also describes computer-controlled methods of large-scaled optics production and testing, including high aspherical, off-axis and thin mirrors, using the examples of production of mirrors at JSC LZOS.

  14. Generating domain specific sentiment lexicons using the Web Directory

    Directory of Open Access Journals (Sweden)

    Akshay Minocha

    2012-10-01

    Full Text Available based. There has been a demand for the construction of generated and labeled sentiment lexicon. Fordata on the social web (E.g., tweets, methods which make use of the synonymy relation don't work well,as we completely ignore the significance of terms belonging to specific domains. Here we propose togenerate a sentiment lexicon for any domain specified, using a twofold method. First we build sentimentscores using the micro-blogging data, and then we use these scores on the ontological structure providedby Open Directory Project [1], to build a custom sentiment lexicon for analyzing domain specific microbloggingdata.

  15. Extracavity and external cavity second-harmonic generation in a periodically poled silica fibre

    Science.gov (United States)

    Dontsova, E. I.; Kablukov, S. I.; Lobach, I. A.; Dostovalov, A. V.; Babin, S. A.; Gladyshev, A. V.; Dianov, E. M.; Corbary, C.; Ibsen, M.; Kazansky, P. G.

    2016-11-01

    We have studied second-harmonic generation (SHG) of a cw single-frequency ytterbium-doped fibre laser, using a periodically poled silica fibre as a nonlinear medium for frequency conversion. All-fibre external cavity SHG has been investigated for the first time. A twofold increase in second-harmonic power in a fibre ring cavity has been demonstrated and possibilities of further optimising the fibre scheme have been analysed.

  16. Afocal three-mirror anastigmat with zigzag optical axis for widened field of view and enlarged aperture

    Science.gov (United States)

    Li, Qi; Han, Lin; Jin, Yangming; Shen, Weimin

    2016-10-01

    In order to improve the detection accuracy and range of new generation of Forward Looking Infra-Red (FLIR) system for distant targets, its optical system, which usually consists of a fore afocal telescope and rear imaging lenses, is required to has wide spectral range, large entrance pupil aperture, and wide field of view (FOV). In this paper, a new afocal Three-Mirror Anastigmat (TMA) with widened field of view and high demagnification is suggested. Its mechanical structure remains coaxial, but it has zigzag optical axis through properly and slightly decentering and tilting of the three mirrors to avoid its secondary obscuration due to the third mirror as FOV increase. Compared with conventional off-axis TMA, the suggested zigzag-axis TMA is compact, easy-alignment and low-cost. The design method and optimum result of the suggested afocal TMA is presented. Its initial structural parameters are determined with its first-order relationship and primary aberration theory. Slight and proper decentration and tilt of each mirror is leaded in optimization so that its coaxial mechanical structure is held but attainable FOV and demagnification are respectively as wide and as high as possible. As an example, a 5.5-demagnification zigzag-axis afocal TMA with a wavelength range, an entrance pupil diameter, and FOV respectively from 3μm to 12μm, of 320mm, and 2×3.2 degrees and with a real exit pupil, is designed. Its imaging quality is diffraction limited. It is suitable for fore afocal telescope of the so-called third generation FLIR.

  17. The T2K ND280 Off-Axis Pi-Zero Detector

    CERN Document Server

    Assylbekov, S; Berns, H; Beznosko, D; Bodek, A; Bradford, R; Buchanan, N; Budd, H; Caffari, Y; Connolly, K; Danko, I; Das, R; Davis, S; Day, M; Dytman, S; Dziomba, M; Flight, R; Forbush, D; Gilje, K; Hansen, D; Hignight, J; Imber, J; Johnson, R A; Jung, C K; Kravtsov, V; Le, P T; Lopez, G D; Malafis, C J; Manly, S; Marino, A D; McFarland, K S; McGrew, C; Metelko, C; Nagashima, G; Naples, D; Nielsen, B; Paolone, V; Paul, P; Qian, W; Ramos, K; Rodrigues, P A; Ruterbories, D; Schmidt, J; Schwehr, J; Siyad, M; Steffens, J; Tadepalli, A S; Taylor, I J; Toki, W; Vanek, C; Warner, D; Weber, A; Wilkes, R J; Wilson, R J; Yanagisawa, C; Yuan, T

    2011-01-01

    The Pi-Zero detector (P{\\O}D) is one of the subdetectors that makes up the off-axis near detector for the Tokai-to-Kamioka (T2K) long baseline neutrino experiment. The primary goal for the P{\\O}D is to measure the relevant cross sections for neutrino interactions that generate pi-zero's, especially the cross section for neutral current pi-zero interactions, which are one of the dominant sources of background to the electron neutrino appearance signal in T2K. The P{\\O}D is composed of layers of plastic scintillator alternating with water bags and brass sheets or lead sheets and is one of the first detectors to use Multi-Pixel Photon Counters (MPPCs) on a large scale.

  18. Moment of Inertia Dependence of Vertical Axis Wind Turbines in Pulsating Winds

    Directory of Open Access Journals (Sweden)

    Yutaka Hara

    2012-01-01

    Full Text Available Vertical Axis Wind Turbines (VAWTs are unaffected by changes in wind direction, and they have a simple structure and the potential for high efficiency due to their lift driving force. However, VAWTs are affected by changes in wind speed, owing to effects originating from the moment of inertia. In this study, changes in the rotational speed of a small VAWT in pulsating wind, generated by an unsteady wind tunnel, are investigated by varying the wind cycle and amplitude parameters. It is shown that the responses observed experimentally agree with simulations based on torque characteristics obtained under steady rotational conditions. Additionally, a simple equation expressing the relationship between the rotational change width and amplitude of the pulsating wind is presented. The energy efficiency in a pulsating wind remains constant with changes in both the moment of inertia and the wind cycle; however, the energy efficiency decreases when the wind amplitude is large.

  19. Highly Effective New Treatments for Psoriasis Target the IL-23/Type 17 T Cell Autoimmune Axis.

    Science.gov (United States)

    Kim, Jaehwan; Krueger, James G

    2017-01-14

    Psoriasis vulgaris, affecting the skin, is one of the most common organ-specific autoimmune diseases in humans. Until recently, psoriasis was treated by agents or approaches discovered largely through serendipity. Many of the available drugs were inherently quite toxic when used as continuous treatment for many years in this chronic disease. However, an increasing understanding of disease-specific immune pathways has spurred development of pathway-targeted therapeutics during the past decade. Psoriasis is now the most effectively treated human autoimmune disease, with high-level clinical improvements possible in ∼90% of patients using a new generation of drugs that selectively target the IL-23/Type 17 T cell axis. Thus, psoriasis is a model for the success of a translational-medicine approach based on cellular and molecular dissection of disease pathogenesis in humans.

  20. EVALUATION OF PERFORMANCE OF HORIZONTAL AXIS WIND TURBINE BLADES BASED ON OPTIMAL ROTOR THEORY

    Directory of Open Access Journals (Sweden)

    Nitin Tenguria

    2011-01-01

    Full Text Available Wind energy is a very popular renewable energy resource. In order to increase the use of wind energy, it is important to develop wind turbine rotor with high rotations rates and power coefficient. In this paper, a method for the determination of the aerodynamic performance characteristics using NACA airfoils is given for three bladed horizontal axis wind turbine. Blade geometry is obtained from the best approximation of the calculated theoretical optimum chord and twist distribution of the rotating blade. Optimal rotor theory is used, which is simple enough and accurate enough for rotor design. In this work, eight different airfoils are used to investigate the changes in performance of the blade. Rotor diameter taken is 82 m which is the diameter of VESTAS V82-1.65MW. The airfoils taken are same from root to tip in every blade. The design lift coefficient taken is 1.1. A computer program is generated to automate the complete procedure.

  1. EVALUATION OF PERFORMANCE OF HORIZONTAL AXIS WIND TURBINE BLADES BASED ON OPTIMAL ROTOR THEORY

    Directory of Open Access Journals (Sweden)

    Nitin Tenguria

    2011-06-01

    Full Text Available Wind energy is a very popular renewable energy resource. In order to increase the use of wind energy, it is important to develop wind turbine rotor with high rotations rates and power coefficient. In this paper, a method for the determination of the aerodynamic performance characteristics using NACA airfoils is given for three bladed horizontal axis wind turbine. Blade geometry is obtained from the best approximation of the calculated theoretical optimum chord and twist distribution of the rotating blade. Optimal rotor theory is used, which is simple enough and accurate enough for rotor design. In this work, eight different airfoils are used to investigate the changes in performance of the blade. Rotor diameter taken is 82 m which is the diameter of VESTAS V82-1.65MW. The airfoils taken are same from root to tip in every blade. The design lift coefficient taken is 1.1. A computer program is generated to automate the complete procedure.

  2. Microfabrication of Three-Axis Tactile Feedback Actuator for Robot-Assisted Surgery

    Science.gov (United States)

    Doh, Eunhyup; Yoo, Jihyung; Lee, Hyungkew; Park, Joonah; Yun, Kwang-Seok

    2013-01-01

    In this paper, we propose and demonstrate a three-axis tactile feedback actuator using pneumatic balloons for human perception applications such as robot-assisted surgery systems. A tactile actuator is composed of a center structure having four balloons, sidewalls with one lateral balloon on each sidewall, and a bottom structure supporting the center structure. We fabricated the proposed device using flexible poly(dimethylsiloxane) and hard polyurethane with final dimensions of 18 ×18 ×18 mm3. The four balloons on the center structure produce normal tactile display during pneumatic-pressure-assisted inflation. The lateral movement of the center structure driven by sidewall balloons generates a shear tactile display on fingertips. The center deflections of the circular and rectangular balloons were calculated and measured experimentally.

  3. Visual Servoing of a Conventional CNC Machine Using an External Axis Controller

    Directory of Open Access Journals (Sweden)

    Daniel Hanafi

    2003-04-01

    Full Text Available This paper presents the implementation of an external axis control system on a conventional CNC machine so that the machine can be actively controlled in response to sensors such as vision and force. The controller that runs on an external computer has direct access to the CNC controller for machine position sensing. The control signals to the machine are sent through purpose built circuitry via the machine's manual pulse generator (MPG inputs. To demonstrate the accuracy and performance of the control system, it was used to visually track the profile of a mandrel used for shear spinning. The implemented system eliminates the parallax error and the need to use an accurate pixel resolution. The raw tracking data is processed by a curvature detection algorithm that detects linear and circular segments and segment transitions. The results show that the visual tracking system provides accurate tracking results that are well within the tolerances used in the industry.

  4. A novel "complement-metabolism-inflammasome axis" as a key regulator of immune cell effector function.

    Science.gov (United States)

    Arbore, Giuseppina; Kemper, Claudia

    2016-07-01

    The inflammasomes are intracellular multiprotein complexes that induce and regulate the generation of the key pro-inflammatory cytokines IL-1β and IL-18 in response to infectious microbes and cellular stress. The activation of inflammasomes involves several upstream signals including classic pattern or danger recognition systems such as the TLRs. Recently, however, the activation of complement receptors, such as the anaphylatoxin C3a and C5a receptors and the complement regulator CD46, in conjunction with the sensing of cell metabolic changes, for instance increased amino acid influx and glycolysis (via mTORC1), have emerged as additional critical activators of the inflammasome. This review summarizes recent advances in our knowledge about complement-mediated inflammasome activation, with a specific focus on a novel "complement - metabolism - NLRP3 inflammasome axis."

  5. Location of aerodynamic noise sources from a 200 kW vertical-axis wind turbine

    Science.gov (United States)

    Ottermo, Fredric; Möllerström, Erik; Nordborg, Anders; Hylander, Jonny; Bernhoff, Hans

    2017-07-01

    Noise levels emitted from a 200 kW H-rotor vertical-axis wind turbine have been measured using a microphone array at four different positions, each at a hub-height distance from the tower. The microphone array, comprising 48 microphones in a spiral pattern, allows for directional mapping of the noise sources in the range of 500 Hz to 4 kHz. The produced images indicate that most of the noise is generated in a narrow azimuth-angle range, compatible with the location where increased turbulence is known to be present in the flow, as a result of the previous passage of a blade and its support arms. It is also shown that a semi-empirical model for inflow-turbulence noise seems to produce noise levels of the correct order of magnitude, based on the amount of turbulence that could be expected from power extraction considerations.

  6. The T2K ND280 off-axis pi-zero detector

    Energy Technology Data Exchange (ETDEWEB)

    Assylbekov, S. [Colorado State University, Department of Physics, Fort Collins, CO (United States); Barr, G. [Oxford University, Department of Physics, Oxford (United Kingdom); Berger, B.E. [Colorado State University, Department of Physics, Fort Collins, CO (United States); Berns, H. [University of Washington, Department of Physics, Seattle, WA (United States); Beznosko, D. [State University of New York at Stony Brook, Department of Physics and Astronomy, Stony Brook, NY (United States); Bodek, A.; Bradford, R. [University of Rochester, Department of Physics and Astronomy, Rochester, NY (United States); Buchanan, N. [Colorado State University, Department of Physics, Fort Collins, CO (United States); Budd, H. [University of Rochester, Department of Physics and Astronomy, Rochester, NY (United States); Caffari, Y. [Colorado State University, Department of Physics, Fort Collins, CO (United States); Connolly, K. [University of Washington, Department of Physics, Seattle, WA (United States); Danko, I. [University of Pittsburgh, Department of Physics and Astronomy, Pittsburgh, PA (United States); Das, R. [Colorado State University, Department of Physics, Fort Collins, CO (United States); Davis, S. [University of Washington, Department of Physics, Seattle, WA (United States); Day, M. [University of Rochester, Department of Physics and Astronomy, Rochester, NY (United States); Dytman, S. [University of Pittsburgh, Department of Physics and Astronomy, Pittsburgh, PA (United States); Dziomba, M. [University of Washington, Department of Physics, Seattle, WA (United States); Flight, R. [University of Rochester, Department of Physics and Astronomy, Rochester, NY (United States); Forbush, D. [University of Washington, Department of Physics, Seattle, WA (United States); Gilje, K. [State University of New York at Stony Brook, Department of Physics and Astronomy, Stony Brook, NY (United States); and others

    2012-09-11

    The pi-zero detector (POD) is one of the subdetectors that makes up the off-axis near detector for the Tokai-to-Kamioka (T2K) long baseline neutrino experiment. The primary goal for the POD is to measure the relevant cross-sections for neutrino interactions that generate {pi}{sup 0}'s, especially the cross-section for neutral current {pi}{sup 0} interactions, which are one of the dominant sources of background to the {nu}{sub {mu}}{yields}{nu}{sub e} appearance signal in T2K. The POD is composed of layers of plastic scintillator alternating with water bags and brass sheets or lead sheets and is one of the first detectors to use Multi-Pixel Photon Counters (MPPCs) on a large scale.

  7. Coherent Structure Dynamics and Turbulent Effects of Horizontal Axis Marine Energy Devices

    Science.gov (United States)

    Gajardo, D. I.; Escauriaza, C. R.; Ingram, D.

    2016-12-01

    Harnessing the energy available in the oceans constitutes one of the most promising alternatives for generating clean electricity. There are vast amounts of energy present both in waves and tidal currents so it is anticipated that marine energy will have a major role in non-conventional renewable energy generation in the near to mid future. Nevertheless, before marine hydrokinetic (MHK) devices can be installed in large numbers a better understanding of the physical, social and environmental implications of their operation is needed. This includes understanding the: hydrodynamic processes, interaction with bathymetry, and the local flow characteristics. This study is focused on the effects horizontal axis MHK devices have on flow turbulence and coherent structures. This is especially relevant considering that sites with favourable conditions for MHK devices are tidal channels where a delicate balance exists between the strong tidal currents and the ecosystems. Understanding how MHK devices influence flow conditions, turbulence and energy flux is essential for predicting and assessing the environmental implications of deploying MHK technologies. We couple a Blade Element Momentum Actuator Disk (BEM-AD) model to a Detached Eddy Simulation (DES) flow solver in order to study flow conditions for different configurations of horizontal axis MHK turbines. In this study, we contribute to the understanding of the hydrodynamic behaviour of MHK technologies, and give insights into the effects devices will have on their environment, with emphasis in ambient turbulence and flow characteristics, while keeping in mind that these effects can alter electricity quality and device performance. Work supported by CONICYT grant 80160084, Fondecyt grant 1130940, Chile's Marine Energy Research & Innovation Center (MERIC) CORFO project 14CEI2-28228, and the collaboration between the Pontificia Universidad Católica de Chile and the University of Edinburgh, UK, partially supported by the RC

  8. Microwave generator

    Science.gov (United States)

    Kwan, T.J.T.; Snell, C.M.

    1987-03-31

    A microwave generator is provided for generating microwaves substantially from virtual cathode oscillation. Electrons are emitted from a cathode and accelerated to an anode which is spaced apart from the cathode. The anode has an annular slit there through effective to form the virtual cathode. The anode is at least one range thickness relative to electrons reflecting from the virtual cathode. A magnet is provided to produce an optimum magnetic field having the field strength effective to form an annular beam from the emitted electrons in substantial alignment with the annular anode slit. The magnetic field, however, does permit the reflected electrons to axially diverge from the annular beam. The reflected electrons are absorbed by the anode in returning to the real cathode, such that substantially no reflexing electrons occur. The resulting microwaves are produced with a single dominant mode and are substantially monochromatic relative to conventional virtual cathode microwave generators. 6 figs.

  9. Solar Generator

    Science.gov (United States)

    1985-01-01

    The Vanguard I dish-Stirling module program, initiated in 1982, produced the Vanguard I module, a commercial prototype erected by the Advanco Corporation. The module, which automatically tracks the sun, combines JPL mirrored concentrator technology, an advanced Stirling Solar II engine/generator, a low cost microprocessor-controlled parabolic dish. Vanguard I has a 28% sunlight to electricity conversion efficiency. If tests continue to prove the system effective, Advanco will construct a generating plant to sell electricity to local utilities. An agreement has also been signed with McDonnell Douglas to manufacture a similar module.

  10. Mode matching for optimal plasmonic nonlinear generation

    Science.gov (United States)

    O'Brien, Kevin; Suchowski, Haim; Rho, Jun Suk; Kante, Boubacar; Yin, Xiaobo; Zhang, Xiang

    2013-03-01

    Nanostructures and metamaterials have attracted interest in the nonlinear optics community due to the possibility of engineering their nonlinear responses; however, the underlying physics to describe nonlinear light generation in nanostructures and the design rules to maximize the emission are still under debate. We study the geometry dependence of the second harmonic and third harmonic emission from gold nanostructures, by designing arrays of nanostructures whose geometry varies from bars to split ring resonators. We fix the length (and volume) of the nanostructure on one axis, and change the morphology from a split ring resonator on the other axis. We observed that the optimal second harmonic generation does not occur at the morphology indicated by a nonlinear oscillator model with parameters derived from the far field transmission and is not maximized by a spectral overlap of the plasmonic modes; however, we find a near field overlap integral and mode matching considerations accurately predict the optimal geometry.

  11. Wind wheel electric power generator

    Science.gov (United States)

    Kaufman, J. W. (Inventor)

    1980-01-01

    Wind wheel electric power generator apparatus includes a housing rotatably mounted upon a vertical support column. Primary and auxiliary funnel-type, venturi ducts are fixed onto the housing for capturing wind currents and conducting to a bladed wheel adapted to be operatively connected with the generator apparatus. Additional air flows are also conducted onto the bladed wheel; all of the air flows positively effecting rotation of the wheel in a cumulative manner. The auxiliary ducts are disposed at an acute angle with respect to the longitudinal axis of the housing, and this feature, together with the rotatability of the housing and the ducts, permits capture of wind currents within a variable directional range.

  12. Effect of Relative Marker Movement on the Calculation of the Foot Torsion Axis Using a Combined Cardan Angle and Helical Axis Approach

    Directory of Open Access Journals (Sweden)

    Eveline S. Graf

    2012-01-01

    Full Text Available The two main movements occurring between the forefoot and rearfoot segment of a human foot are flexion at the metatarsophalangeal joints and torsion in the midfoot. The location of the torsion axis within the foot is currently unknown. The purpose of this study was to develop a method based on Cardan angles and the finite helical axis approach to calculate the torsion axis without the effect of flexion. As the finite helical axis method is susceptible to error due to noise with small helical rotations, a minimal amount of rotation was defined in order to accurately determine the torsion axis location. Using simulation, the location of the axis based on data containing noise was compared to the axis location of data without noise with a one-sample t-test and Fisher's combined probability score. When using only data with helical rotation of seven degrees or more, the location of the torsion axis based on the data with noise was within 0.2 mm of the reference location. Therefore, the proposed method allowed an accurate calculation of the foot torsion axis location.

  13. Effect of relative marker movement on the calculation of the foot torsion axis using a combined Cardan angle and helical axis approach.

    Science.gov (United States)

    Graf, Eveline S; Wright, Ian C; Stefanyshyn, Darren J

    2012-01-01

    The two main movements occurring between the forefoot and rearfoot segment of a human foot are flexion at the metatarsophalangeal joints and torsion in the midfoot. The location of the torsion axis within the foot is currently unknown. The purpose of this study was to develop a method based on Cardan angles and the finite helical axis approach to calculate the torsion axis without the effect of flexion. As the finite helical axis method is susceptible to error due to noise with small helical rotations, a minimal amount of rotation was defined in order to accurately determine the torsion axis location. Using simulation, the location of the axis based on data containing noise was compared to the axis location of data without noise with a one-sample t-test and Fisher's combined probability score. When using only data with helical rotation of seven degrees or more, the location of the torsion axis based on the data with noise was within 0.2 mm of the reference location. Therefore, the proposed method allowed an accurate calculation of the foot torsion axis location.

  14. Adolescent Survivors of Hurricane Katrina: A Pilot Study of Hypothalamic-Pituitary-Adrenal Axis Functioning

    Science.gov (United States)

    Pfefferbaum, Betty; Tucker, Phebe; Nitiéma, Pascal

    2015-01-01

    Background: The hypothalamic-pituitary-adrenal (HPA) axis constitutes an important biological component of the stress response commonly studied through the measurement of cortisol. Limited research has examined HPA axis dysregulation in youth exposed to disasters. Objective: This study examined HPA axis activation in adolescent Hurricane Katrina…

  15. Research on identifying the dynamic error model of strapdown gyro on 3-axis turntable

    Institute of Scientific and Technical Information of China (English)

    WANG Hai; REN Shun-qing; WANG Chang-hong

    2005-01-01

    The dynamic errors of gyros are the important error sources of a strapdown inertial navigation system.In order to identify the dynamic error model coefficients accurately, the static erTor model coefficients which lay a foundation for compensating while identifying the dynamic error model are identified in the gravity acceleration fields by using angular position function of the three-axis turntable. The angular acceleration and angular velocity are excited on the input, output and spin axis of the gyros when the outer axis and the middle axis of a threeaxis turntable are in the uniform angular velocity state simultaneously, while the inner axis of the turntable is in different static angular positions. 8 groups of data are sampled when the inner axis is in 8 different angular positions. These data are the function of the middle axis positions and the inner axis positions. For these data, harmonic analysis method is applied two times versus the middle axis positions and inner axis positions respectively so that the dynamic error model coefficients are finally identified through the least square method. In the meantime the optimal angular velocity of the outer axis and the middle axis are selected by computing the determination value of the information matrix.

  16. Hypothalamic-pituitary-adrenal axis activity in older persons with and without a depressive disorder

    NARCIS (Netherlands)

    Rhebergen, D.; Korten, N. C. M.; Penninx, B. W. J. H.; Stek, M. L.; van der Mast, R. C.; Voshaar, R. Oude; Comijs, H. C.

    2015-01-01

    Background: Altered functioning of the hypothalamic-pituitary-adrenal axis (HPA-axis) has been associated with depression, but findings have been inconsistent. Among older depressed persons, both hyperactivity and hypo-activity of the HPA-axis were demonstrated. However, most studies were population

  17. Multiscale mathematical modeling of the hypothalamo-pituitary-gonadal axis.

    Science.gov (United States)

    Clément, Frédérique

    2016-07-01

    Although the fields of systems and integrative biology are in full expansion, few teams are involved worldwide into the study of reproductive function from the mathematical modeling viewpoint. This may be due to the fact that the reproductive function is not compulsory for individual organism survival, even if it is for species survival. Alternatively, the complexity of reproductive physiology may be discouraging. Indeed, the hypothalamo-pituitary-gonadal (HPG) axis involves not only several organs and tissues but also intricate time (from the neuronal millisecond timescale to circannual rhythmicity) and space (from molecules to organs) scales. Yet, mathematical modeling, and especially multiscale modeling, can renew our approaches of the molecular, cellular, and physiological processes underlying the control of reproductive functions. In turn, the remarkable dynamic features exhibited by the HPG axis raise intriguing and challenging questions to modelers and applied mathematicians. In this article, we draw a panoramic review of some mathematical models designed in the framework of the female HPG, with a special focus on the gonadal and central control of follicular development. On the gonadal side, the modeling of follicular development calls to the generic formalism of structured cell populations, that allows one to make mechanistic links between the control of cell fate (proliferation, differentiation, or apoptosis) and that of the follicle fate (ovulation or degeneration) or to investigate how the functional interactions between the oocyte and its surrounding cells shape the follicle morphogenesis. On the central, mainly hypothalamic side, models based on dynamical systems with multiple timescales allow one to represent within a single framework both the pulsatile and surge patterns of the neurohormone GnRH. Beyond their interest in basic research investigations, mathematical models can also be at the source of useful tools to study the encoding and decoding of

  18. Kynurenine pathway metabolism and the microbiota-gut-brain axis.

    Science.gov (United States)

    Kennedy, P J; Cryan, J F; Dinan, T G; Clarke, G

    2017-01-01

    It has become increasingly clear that the gut microbiota influences not only gastrointestinal physiology but also central nervous system (CNS) function by modulating signalling pathways of the microbiota-gut-brain axis. Understanding the neurobiological mechanisms underpinning the influence exerted by the gut microbiota on brain function and behaviour has become a key research priority. Microbial regulation of tryptophan metabolism has become a focal point in this regard, with dual emphasis on the regulation of serotonin synthesis and the control of kynurenine pathway metabolism. Here, we focus in detail on the latter pathway and begin by outlining the structural and functional dynamics of the gut microbiota and the signalling pathways of the brain-gut axis. We summarise preclinical and clinical investigations demonstrating that the gut microbiota influences CNS physiology, anxiety, depression, social behaviour, cognition and visceral pain. Pertinent studies are drawn from neurogastroenterology demonstrating the importance of tryptophan and its metabolites in CNS and gastrointestinal function. We outline how kynurenine pathway metabolism may be regulated by microbial control of neuroendocrine function and components of the immune system. Finally, preclinical evidence demonstrating direct and indirect mechanisms by which the gut microbiota can regulate tryptophan availability for kynurenine pathway metabolism, with downstream effects on CNS function, is reviewed. Targeting the gut microbiota represents a tractable target to modulate kynurenine pathway metabolism. Efforts to develop this approach will markedly increase our understanding of how the gut microbiota shapes brain and behaviour and provide new insights towards successful translation of microbiota-gut-brain axis research from bench to bedside. This article is part of the Special Issue entitled 'The Kynurenine Pathway in Health and Disease'.

  19. HPA axis dysregulation in men with hypersexual disorder.

    Science.gov (United States)

    Chatzittofis, Andreas; Arver, Stefan; Öberg, Katarina; Hallberg, Jonas; Nordström, Peter; Jokinen, Jussi

    2016-01-01

    Hypersexual disorder integrating pathophysiological aspects such as sexual desire deregulation, sexual addiction, impulsivity and compulsivity was suggested as a diagnosis for the DSM-5. However, little is known about the neurobiology behind this disorder. A dysregulation of the hypothalamic pituitary adrenal (HPA) axis has been shown in psychiatric disorders but has not been investigated in hypersexual disorder. The aim of this study was to investigate the function of the HPA axis in hypersexual disorder. The study includes 67 male patients with hypersexual disorder and 39 healthy male volunteers. Basal morning plasma levels of cortisol and ACTH were assessed and low dose (0.5mg) dexamethasone suppression test was performed with cortisol and ACTH measured post dexamethasone administration. Non-suppression status was defined with DST-cortisol levels ≥ 138 nmol/l. The Sexual Compulsive scale (SCS), Hypersexual disorder current assessment scale (HD:CAS), Montgomery-Åsberg Depression Scale-self rating (MADRS-S) and Childhood trauma questionnaire (CTQ), were used for assessing hypersexual behavior, depression severity and early life adversity. Patients with hypersexual disorder were significantly more often DST non-suppressors and had significantly higher DST-ACTH levels compared to healthy volunteers. The patients reported significantly more childhood trauma and depression symptoms compared to healthy volunteers. CTQ scores showed a significant negative correlation with DST-ACTH whereas SCS and HD:CAS scores showed a negative correlation with baseline cortisol in patients. The diagnosis of hypersexual disorder was significantly associated DST non-suppression and higher plasma DST-ACTH even when adjusted for childhood trauma. The results suggest HPA axis dysregulation in male patients with hypersexual disorder.

  20. Lead Toxicity and The Hypothalamic-Pituitary-Testicular Axis

    Directory of Open Access Journals (Sweden)

    Nadia AIT HAMADOUCHE

    2013-02-01

    Full Text Available Environmental exposure to toxic levels of lead (Pb occurs in a number of industries with potential adverse effects on the reproductive capacity of exposed men. Clinical and animal studies indicate that abnormalities of spermatogenesis result from toxic lead exposure, but eventual histopathologic alterations involved have not been identified. To explore putative abnormalities in the reproductive gonadotropic axis following lead intoxication, experimental animals when exposed to low levels of lead, 65 days old animals were treated with distilled water containing 0, 0 mg (control, 10 mg lead (Pb/Kg/day and 15 mg lead (Pb/Kg/day intraperitoneally for 20 days. At the end of treatment, the animals were sacrificed and the blood collected for luteinizing hormone (LH and testosterone assays. The testis was processed for histological analysis. The results showed a high serum concentration of LH and testosterone in lead-treated animals compared to controls. Histological examination of testis showed deformities in testicular morphology of lead intoxicated animals with gross damage within the somniferous tubules. A strong correlation was established between LH and testosterone suggesting an alteration in the endocrine components of the gonadotropic axis. Histological examination of pituitary gland showed some degenerative changes in endocrine cells of lead group. Changes in LH and testosterone levels suggest that Pb exposure during the critical time of sexual differentiation induces reproductive axis abnormalities in adulthood. In conclusion, lead has a gonadotoxic effect by decreasing LH and testosterone levels and damaging the testis seminiferous tubules. Catalase activity was significantly reduced in the lead group following 65 days of exposure which possibly indicates that lead might had other mechanisms of action, such as increasing oxidative damage.

  1. Unsteady loading of a vertical-axis turbine in the interaction with an upstream deflector

    Science.gov (United States)

    Kim, Daegyoum; Gharib, Morteza

    2014-01-01

    Torque generation and flow distribution of a lift-based vertical-axis turbine with an upstream deflecting plate are investigated in water tunnel experiments. The deployment of a deflector in front of a lift-based turbine is a promising approach to increase local flow velocity and enhance energy conversion efficiency without consideration for complicated control. For the turbine with the deflector, the phase during which the blade passes near the front end of the turbine has a major contribution to torque increase from the case without the deflector. Meanwhile, the deflector can have a negative effect in torque generation at the phase when the blade moves upstream against free stream if the turbine is placed close to the deflector in a crosswise direction. The change of nearby flow distribution by the deflector is also examined to find its correlation with torque generation. When the blade rotates through the near-wake region of the deflector, the blade can collides with the vortical structure shed from the deflector. This interaction causes significant torque fluctuation.

  2. Development of a 5.5 m diameter vertical axis wind turbine, phase 3

    Science.gov (United States)

    Dekitsch, A.; Etzler, C. C.; Fritzsche, A.; Lorch, G.; Mueller, W.; Rogalla, K.; Schmelzle, J.; Schuhwerk, W.; Vollan, A.; Welte, D.

    1982-06-01

    In continuation of development of a 5.5 m diameter vertical axis windmill that consists in conception, building, and wind tunnel testing, a Darrieus rotor windpowered generator feeding an isolated network under different wind velocity conditions and with optimal energy conversion efficiency was designed built, and field tested. The three-bladed Darrieus rotor tested in the wind tunnel was equiped with two variable pitch Savonius rotors 2 m in diameter. By means of separate measures of the aerodynamic factors and the energy consumption, effect of revisions and optimizations on different elements was assessed. Pitch adjustement of the Savonius blades, lubrication of speed reducer, rotor speed at cut-in of generator field excitation, time constant of field excitation, stability conditions, switch points of ohmic resistors which combined with a small electric battery simulated a larger isolated network connected with a large storage battery, were investigated. Fundamentals for the economic series production of windpowered generators with Darrieus rotors for the control and the electric conversion system are presented.

  3. Studi Eksperimental Vertical Axis Wind Turbine Tipe Savonius dengan Variasi Jumlah Fin pada Sudu

    Directory of Open Access Journals (Sweden)

    Ola Dwi Sandra Hasan

    2013-09-01

    Full Text Available Salah satu  teknologi sistem konversi energi angin  yang ada adalah turbin Savonius yang merupakan salah satu jenis Vertical Axis Wind Turbine ( VAWT . Turbin Savonius  memiliki  karakteristik strating torsi yang baik, mudah dalam pembutannya dan dapat menerima angin dari segala arah namun kekurangan yang dimiliki adalah coefficient of power (Cp turbin yang rendah. Untuk itu banyak dilakukan penelitian untuk meningkatkan efisiensi dari turbin Savonius. Salah satunya adalah penambahan end plate yang mampu meningkatkan perbedaan tekanan dari kedua sisi sudu sehingga memperbesar drag positif turbin. Untuk itu pada penelitian ini dilakukan variasi jumlah penambahan fin pada sudu. Variasi jumlah fin yang dilakukan adalah 1,2,4 dan 7 fin serta pengujian dengan menggunakan generator dan tanpa generator. Dari hasil pengujian, variasi fin yang dapat meningkatkan Cp turbin Savonius adalah variasi 1 fin jika dibandingkan  turbin standarnya dengan nilai Cp sebesar 0,11.  SKEA turbin Savonius menggunakan generator 12 V;400W dapat  menghasilkan daya maksimal 5,71 Watt pada putaran 134 rpm

  4. MAS-mediated antioxidant effects restore the functionality of angiotensin converting enzyme 2-angiotensin-(1-7)-MAS axis in diabetic rat carotid.

    Science.gov (United States)

    Pernomian, Larissa; Gomes, Mayara Santos; Restini, Carolina Baraldi Araujo; de Oliveira, Ana Maria

    2014-01-01

    We hypothesized that endothelial AT1-activated NAD(P)H oxidase-driven generation of reactive oxygen species during type I-diabetes impairs carotid ACE2-angiotensin-(1-7)-Mas axis functionality, which accounts for the impaired carotid flow in diabetic rats. We also hypothesized that angiotensin-(1-7) chronic treatment of diabetic rats restores carotid ACE2-angiotensin-(1-7)-Mas axis functionality and carotid flow. Relaxant curves for angiotensin II or angiotensin-(1-7) were obtained in carotid from streptozotocin-induced diabetic rats. Superoxide or hydrogen peroxide levels were measured by flow cytometry in carotid endothelial cells. Carotid flow was also determined. We found that endothelial AT1-activated NAD(P)H oxidase-driven generation of superoxide and hydrogen peroxide in diabetic rat carotid impairs ACE2-angiotensin-(1-7)-Mas axis functionality, which reduces carotid flow. In this mechanism, hydrogen peroxide derived from superoxide dismutation inhibits ACE2 activity in generating angiotensin-(1-7) seemingly by activating I(Cl,SWELL0, while superoxide inhibits the nitrergic Mas-mediated vasorelaxation evoked by angiotensin-(1-7). Angiotensin-(1-7) treatment of diabetic rats restored carotid ACE2-angiotensin-(1-7)-Mas axis functionality by triggering a positive feedback played by endothelial Mas receptors, that blunts endothelial AT1-activated NAD(P)H oxidase-driven generation of reactive oxygen species. Mas-mediated antioxidant effects also restored diabetic rat carotid flow, pointing to the contribution of ACE2-angiotensin-(1-7)-Mas axis in maintaining carotid flow.

  5. Generation and dynamics of optical beams with polarization singularities

    CERN Document Server

    Cardano, Filippo; Marrucci, Lorenzo; de Lisio, Corrado; Santamato, Enrico

    2013-01-01

    We present a convenient method to generate vector beams of light having polarization singularities on their axis, via partial spin-to-orbital angular momentum conversion in a suitably patterned liquid crystal cell. The resulting polarization patterns exhibit a C-point on the beam axis and an L-line loop around it, and may have different geometrical structures such as \\qo{lemon}, \\qo{star}, and \\qo{vortex}. Our generation method allows us to control the radius of L-line loop around the central C-point. Moreover, we investigate the free-air propagation of these fields across a Rayleigh range.

  6. Generation and dynamics of optical beams with polarization singularities.

    Science.gov (United States)

    Cardano, Filippo; Karimi, Ebrahim; Marrucci, Lorenzo; de Lisio, Corrado; Santamato, Enrico

    2013-04-08

    We present a convenient method to generate vector beams of light having polarization singularities on their axis, via partial spin-to-orbital angular momentum conversion in a suitably patterned liquid crystal cell. The resulting polarization patterns exhibit a C-point on the beam axis and an L-line loop around it, and may have different geometrical structures such as "lemon", "star", and "spiral". Our generation method allows us to control the radius of L-line loop around the central C-point. Moreover, we investigate the free-air propagation of these fields across a Rayleigh range.

  7. Impedances and power losses for an off-axis beam

    CERN Document Server

    Kurennoy, S S

    1996-01-01

    A method for calculating coupling impedances and power losses for off-axis beams is developed. It is applied to calculate impedances of small localized discontinuities like holes and slots, as well as the impedance due to a finite resistivity of chamber walls, in homogeneous chambers with an arbitrary shape of the chamber cross section. The approach requires to solve a two-dimensional electrostatic problem, which can be easily done numerically in the general case, while for some particular cases analytical solutions are obtained.

  8. Smart phone orientation estimation comparisons using three axis gimbal

    Science.gov (United States)

    Gaquin, Kevin G.; Fields, MaryAnne

    2016-05-01

    Smartphones have put powerful sensor arrays in nearly everyone's pockets. Fusing the data from these sensors it is possible to estimate the phone's current orientation. In this study we utilize a 3 axis gimbal to compare the performance of multiple orientation estimation algorithms. Controlling the position of the gimbal allows us to compare the known device orientation to the estimated orientation. Using this same method we determine where each algorithm's faults lie, and where they begin to break down. Then repeating these movements we are able to compare each algorithm to each other.

  9. Design of tracking photovoltaic systems with a single vertical axis

    Energy Technology Data Exchange (ETDEWEB)

    Lorenzo, E. [Ciudad Universitaria, Madrid (Spain). Instituto de Energeia Solar; Perez, M. [Pol Industrial La Nava, Naavarrsa (Spain). Alternativas Energeticas Solares; Ezpeleta, A. [Energia Hidroelectrica Navarra, Pamplona (Spain); Acedo, J. [Ingeteam SA, Pamplona (Spain)

    2002-07-01

    Solar tracking is used in large grid-connected photovoltaic plants to maximise solar radiation collection and, hence, to reduce the cost of delivered electricity. In particular, single vertical axis tracking, also called azimuth tracking, allows for energy gains up to 40%, compared with optimally tilted fully static arrays. This paper examines the theoretical aspects associated with the design of azimuth tracking, taking into account shadowing between different trackers and back-tracking features. Then, the practical design of the trackers installed at the 1.4 MW Tudela PV plant is presented and discussed. Finally, this tracking alternative is compared with the more conventional fully stationary approach. (author)

  10. Local charge measurement using off-axis electron holography

    DEFF Research Database (Denmark)

    Beleggia, Marco; Gontard, L.C.; Dunin-Borkowski, R.0E.

    2016-01-01

    A model-independent approach based on Gauss’ theorem for measuring the local charge in a specimen from an electron-optical phase image recorded using off-axis electron holography was recently proposed. Here, we show that such a charge measurement is reliable when it is applied to determine...... the total charge enclosed within an object. However, the situation is more complicated for a partial charge measurement when the integration domain encloses only part of the object. We analyze in detail the effects on charge measurement of the mean inner potential of the object, of the presence of induced...

  11. Error Model and Accuracy Calibration of 5-Axis Machine Tool

    Directory of Open Access Journals (Sweden)

    Fangyu Pan

    2013-08-01

    Full Text Available To improve the machining precision and reduce the geometric errors for 5-axis machinetool, error model and calibration are presented in this paper. Error model is realized by the theory of multi-body system and characteristic matrixes, which can establish the relationship between the cutting tool and the workpiece in theory. The accuracy calibration was difficult to achieve, but by a laser approach-laser interferometer and laser tracker, the errors can be displayed accurately which is benefit for later compensation.

  12. Dynamic Analysis of Darrieus Vertical Axis Wind Turbine Rotors

    Science.gov (United States)

    Lobitz, D. W.

    1981-01-01

    The dynamic response characteristics of the vertical axis wind turbine (VAWT) rotor are important factors governing the safety and fatigue life of VAWT systems. The principal problems are the determination of critical rotor speeds (resonances) and the assessment of forced vibration response amplitudes. The solution to these problems is complicated by centrifugal and Coriolis effects which can have substantial influence on rotor resonant frequencies and mode shapes. The primary tools now in use for rotor analysis are described and discussed. These tools include a lumped spring mass model (VAWTDYN) and also finite-element based approaches. The accuracy and completeness of current capabilities are also discussed.

  13. Multi-axis analog adaptive feedforward cancellation of cryocooler vibration

    Science.gov (United States)

    Collins, Simon Andrew

    1994-01-01

    The vibration produced by Stirling cryocoolers is incompatible with spacecraft-borne precision-pointing imaging instruments. Thermal considerations prevent the addition of sufficient mechanical isolation to eliminate the effects of this vibration. The objective of this research is the design, analysis, and experimental verification of a multi-axis vibration cancellation system for the expander of a split Stirling cryocooler. Cancellation of the periodic cryocooler vibration is achieved with a set of load cells, a custom three-axis electrodynamic actuator, and a narrowband adaptive feedforward controller. In order to size the actuator, a simple model of the cryocooler's vibration is combined with a first-order analysis of a four-magnet two-return-plate forcing element. While the resulting actuator has sufficient force capability, it exhibits significant nonlinearity. A nonlinear actuator model is developed that accounts for in-plane flexure restraint due to both large-amplitude static deflections and large-amplitude vibrations. Numerical solutions of the nonlinear model accurately reflect jump phenomena and higher harmonics observed in the actuator's response. The adaptive feedforward controller employs the filtered-x least-mean-square (FXLMS) algorithm to update an adaptive filter. Rather than implementing this filter with a digital signal processor (DSP), for which there is little flight heritage, a continuous-time analog realization of the FXLMS filter is selected. Theoretically, the FXLMS filter may be represented by an equivalent linear transfer function. However a comprehensive treatment of factors associated with the actual implementation reveals the limitations of the transfer function representation. Factors such as harmonic distortion of the reference signal and imperfect quadrature are shown to result in frequency-shifted terms in the filter's output. The presence of these output components is confirmed experimentally, and their effect on performance is

  14. The apolipoprotein m-sphingosine-1-phosphate axis

    DEFF Research Database (Denmark)

    Arkensteijn, Bas W C; Berbée, Jimmy F P; Rensen, Patrick C N

    2013-01-01

    Apolipoprotein M (apoM) is a plasma apolipoprotein that mainly associates with high-density lipoproteins. Hence, most studies on apoM so far have investigated its effect on and association with lipid metabolism and atherosclerosis. The insight into apoM biology recently took a major turn. Apo......-receptor-1, affecting the function of endothelial cells, and apoM-deficient mice display impaired endothelial permeability in the lung. This review will focus on the putative biological roles of the new apoM-S1P axis in relation to lipoprotein metabolism, lipid disorders and atherosclerosis....

  15. Design of Five-Axis Ultrasonic Assistant Compound Machine Tool

    Institute of Scientific and Technical Information of China (English)

    Liu Bing刘冰; Fang Fengzhou房丰洲; Xu Zongwei徐宗伟; Zhang Xiaofeng张晓峰

    2015-01-01

    A compound machine tool was designed, which combined rotary ultrasonic assisted grinding, electrical discharge machining (EDM) and multi-axis milling. Experimental results indicated that its positioning accuracy was less than 5.6μm and its repetitive positioning accuracy was less than 1.8μm;the vibration amplitude of ultrasonic grinding system was uniform and stable, and the EDM system worked well and stably.A smooth surface of K9 optical glass component was achieved by the grinding method.

  16. Three-axis atomic magnetometer based on spin precession modulation

    Energy Technology Data Exchange (ETDEWEB)

    Huang, H. C.; Dong, H. F., E-mail: hfdong@buaa.edu.cn; Hu, X. Y.; Chen, L.; Gao, Y. [School of Instrumentation Science and Opto-Electronics Engineering, Beihang University, Beijing 100191 (China)

    2015-11-02

    We demonstrate a three-axis atomic magnetometer with one intensity-modulated pump beam and one orthogonal probe beam. The main field component is measured using the resonance of the pumping light, while the transverse field components are measured simultaneously using the optical rotation of the probe beam modulated by the spin precession. It is an all-optical magnetometer without using any modulation field or radio frequency field. Magnetic field sensitivity of 0.8 pT/Hz{sup 1∕2} is achieved under a bias field of 2 μT.

  17. The cathode test stand for the DARHT second-axis

    Energy Technology Data Exchange (ETDEWEB)

    Fortgang, C.; Monroe, M.; Prono, D. [Los Alamos National Lab., NM (United States); Hudson, C.; Macy, D.; Moy, K. [Bechtel Nevada, Santa Barbara, CA (United States)

    1998-12-31

    The injector for the DARHT second-axis injector will use an 8-in. thermionic dispenser cathode. Because the cathode is relatively large and requires a large amount of heat (5 kW) there are certain engineering issues that need to be addressed, before the DARHT injector reaches the final design stage. The Cathode Test Stand (CTS) will be used to address those concerns. The CTS is a new facility, presently under construction. The CTS will consist of a high-voltage pulse modulator, a high-vacuum diode test-chamber, and a short beam-transport section with diagnostics. This paper discusses the status of the project.

  18. Two-axis solar tracking accomplished through small lateral translations.

    Science.gov (United States)

    Hallas, Justin M; Baker, Katherine A; Karp, Jason H; Tremblay, Eric J; Ford, Joseph E

    2012-09-01

    High-concentration solar-power optics require precise two-axis tracking. The planar micro-optic solar concentrator uses a lenslet array over a planar waveguide with small reflective facets at the focal point of each lenslet to couple incident light into the waveguide. The concentrator can use conventional tracking, tilting the entire assembly, but the system geometry also allows tracking by small lateral translation of the lenslet relative to the waveguide. Here, we experimentally demonstrate such microtracking with the existing concentrator optics and present optimized optical designs for systems with higher efficiency and angle range.

  19. Rates of solar angles for two-axis concentrators

    Science.gov (United States)

    Yung, C. S.; Lansing, F. L.

    1982-01-01

    The Sun's position by the azimuth and elevation angles and its rate of change at any time of day are determined to design 2 axis tracking mechanisms of solar concentrators. The Sun's angles and their rates for selected months of the year (March, June, September and December) and for seven selected atitudes (0, + or - 30, + or - 60, + or - 90) covering both the northern and southern hemispheres were studied. The development of the angle and angle rate analytical expressions for any month, hour of day, and latitude provides the solar concentrator designer with a quantitative determination of the limiting Sun's position and angle rates for an accurate automatic tracking mechanism.

  20. Martian Generation

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Independent, Internet savvy and with their own Martian language, China’s post-90s generation is rewriting the rules of behavior september 14 was the 18th birth-day of Zhang Zhaoyu from Sichuan Province. He is a new student at Peking University,

  1. Generative Contexts

    Science.gov (United States)

    Lyles, Dan Allen

    Educational research has identified how science, technology, engineering, and mathematics (STEM) practice and education have underperforming metrics in racial and gender diversity, despite decades of intervention. These disparities are part of the construction of a culture of science that is alienating to these populations. Recent studies in a social science framework described as "Generative Justice" have suggested that the context of social and scientific practice might be modified to bring about more just and equitable relations among the disenfranchised by circulating the value they and their non-human allies create back to them in unalienated forms. What is not known are the underlying principles of social and material space that makes a system more or less generative. I employ an autoethnographic method at four sites: a high school science class; a farm committed to "Black and Brown liberation"; a summer program geared towards youth environmental mapping; and a summer workshop for Harlem middle school students. My findings suggest that by identifying instances where material affinity, participatory voice, and creative solidarity are mutually reinforcing, it is possible to create educational contexts that generate unalienated value, and circulate it back to the producers themselves. This cycle of generation may help explain how to create systems of justice that strengthen and grow themselves through successive iterations. The problem of lack of diversity in STEM may be addressed not merely by recruiting the best and the brightest from underrepresented populations, but by changing the context of STEM education to provide tools for its own systematic restructuring.

  2. Synchronous generators

    CERN Document Server

    Boldea, Ion

    2005-01-01

    This work begins with an introduction to energy resources and the main electric energy conversion solutions, along with efficiency and environmental merits and demerits. The classification and principles of various electric generator topologies are covered alongside their power ratings and main applications including constant-speed synchronous gene

  3. Radiatively Generated $\

    CERN Document Server

    Joshipura, A S; Joshipura, Anjan S.; Rindani, Saurabh D.

    2003-01-01

    We study the consequences of assuming that the mass scale $\\Delta_{odot}$ corresponding to the solar neutrino oscillations and mixing angle $U_{e3}$ corresponding to the electron neutrino oscillation at CHOOZ are radiatively generated through the standard electroweak gauge interactions. All the leptonic mass matrices having zero $\\Delta_{odot}$ and $U_{e3}$ at a high scale lead to a unique low energy value for the $\\Delta_{odot}$ which is determined by the (known) size of the radiative corrections, solar and the atmospheric mixing angle and the Majorana mass of the neutrino observed in neutrinoless double beta decay. This prediction leads to the following consequences: ($i$) The MSSM radiative corrections generate only the dark side of the solar neutrino solutions. ($ii$) The inverted mass hierarchy ($m,-m,0$) at the high scale fails in generating the LMA solution but it can lead to the LOW or vacuum solutions. ($iii$) The $\\Delta_{odot}$ generated in models with maximal solar mixing at a high scale is zero t...

  4. On- and off-axis spectral emission features from laser-produced gas breakdown plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Harilal, S. S.; Skrodzki, P. J.; Miloshevsky, A.; Brumfield, B. E.; Phillips, M. C.; Miloshevsky, G.

    2017-06-01

    Laser-heated gas breakdown plasmas or sparks emit profoundly in the ultraviolet and visible region of the electromagnetic spectrum with contributions from ionic, atomic, and molecular species. Laser created kernels expand into a cold ambient with high velocities during its early lifetime followed by confinement of the plasma kernel and eventually collapse. However, the plasma kernels produced during laser breakdown of gases are also capable of exciting and ionizing the surrounding ambient medium. Two mechanisms can be responsible for excitation and ionization of surrounding ambient: viz. photoexcitation and ionization by intense ultraviolet emission from the sparks produced during the early times of its creation and/or heating by strong shocks generated by the kernel during its expansion into the ambient. In this study, an investigation is made on the spectral features of on- and off-axis emission features of laser-induced plasma breakdown kernels generated in atmospheric pressure conditions with an aim to elucidate the mechanisms leading to ambient excitation and emission. Pulses from an Nd:YAG laser emitting at 1064 nm with 6 ns pulse duration are used to generate plasma kernels. Laser sparks were generated in air, argon, and helium gases to provide different physical properties of expansion dynamics and plasma chemistry considering the differences in laser absorption properties, mass density and speciation. Point shadowgraphy and time-resolved imaging were used to evaluate the shock wave and spark self-emission morphology at early and late times while space and time resolved spectroscopy is used for evaluating the emission features as well as for inferring plasma fundaments at on- and off-axis. Structure and dynamics of the plasma kernel obtained using imaging techniques are also compared to numerical simulations using computational fluid dynamics code. The emission from the kernel showed that spectral features from ions, atoms and molecules are separated in

  5. High-spin structure of sup 1 sup 8 sup 2 sup , sup 1 sup 8 sup 4 Os in tilted axis cranking approach

    CERN Document Server

    Ansari, A; Onishi, N; Horibata, T

    1999-01-01

    A detailed investigation of the high-spin structures of sup 1 sup 8 sup 2 sup , sup 1 sup 8 sup 4 Os has been carried out following a self-consistent two-dimensional (in the x-z plane) tilted axis cranked HFB approach employing a pairing-plus-quadrupole model interaction Hamiltonian. The tilt angle psi is measured with respect to the x-axis so that psi=90 deg. represents the nuclear symmetry z-axis. We have investigated the variation of the shape parameters for a given value of spin, J (up to J=40) as a function of psi. With the force parameters considered here, we do not find for any J the lowest energy solution corresponding to a tilted axis rotation. However, for spins in the region of the backbend (J approx 16) and beyond, the shape parameters change in a complex manner exhibiting local minima as a function of psi. This implies the importance of the dynamical effects due to the wobbling motion of the rotation axis which warrants treatment through a dynamical theory like the generator coordinate method (GC...

  6. Mechanical strain determines the axis of planar polarity in ciliated epithelia

    OpenAIRE

    2015-01-01

    Epithelia containing multiciliated cells align beating cilia along a common planar axis specified by the conserved planar cell polarity (PCP) pathway. Specification of the planar axis is also thought to require a long-range cue to align the axis globally, but the nature of this cue in ciliated and other epithelia remains poorly understood. We examined this issue using the Xenopus larval skin where ciliary flow aligns to the anterior-posterior (A-P) axis. We first show that a planar axis initi...

  7. Application of Circulation Controlled Blades for Vertical Axis Wind Turbines

    Directory of Open Access Journals (Sweden)

    Velissarios Kourkoulis

    2013-07-01

    Full Text Available The blades of a vertical axis wind turbine (VAWT rotor see an inconsistent angle of attack through its rotation. Consequently, VAWT blades generally use symmetrical aerofoils with a lower lift-to-drag ratio than cambered aerofoils tailored to maximise horizontal axis wind turbine rotor performance. This paper considers the feasibility of circulation controlled (CC VAWT blades, using a tangential air jet to provide lift and therefore power augmentation. However CC blade sections require a higher trailing-edge thickness than conventional sections giving rise to additional base drag. The choice of design parameters is a compromise between lift augmentation, additional base drag as well as the power required to pump the air jet. Although CC technology has been investigated for many years, particularly for aerospace applications, few researchers have considered VAWT applications. This paper considers the feasibility of the technology, using Computational Fluid Dynamics to evaluate a baseline CC aerofoil with different trailing-edge ellipse shapes. Lift and drag increments due to CC are considered within a momentum based turbine model to determine net power production. The study found that for modest momentum coefficients significant net power augmentation can be achieved with a relatively simple aerofoil geometry if blowing is controlled through the blades rotation.

  8. Off-Axis Neutrino Scattering in GRB Central Engines

    CERN Document Server

    George, N D; McGhee, J M; Miller, W A; George, Nathan D.; Kheyfets, Arkady; Ghee, John M. Mc; Miller, Warner A.

    2003-01-01

    The search for an understanding of an energy source great enough to explain the gamma-ray burst (GRB) phenomena has attracted much attention from the astrophysical community since its discovery. In this paper we extend the work of K. Asano and T. Fukuyama, and J. D. Salmonson and J. R. Wilson, and analyze the off-axis contributions to the energy-momentum deposition rate (MDR) from the neutrino anti-neutrino collisions above a rotating black hole/thin accretion disk system. Our calculations are performed by imaging the accretion disk at a specified observer using the full geodesic equations, and calculating the cumulative MDR from the scattering of all pairs of neutrinos and anti-neutrinos arriving at the observer. Our results shed light on the beaming efficiency of GRB models of this kind. Although we confirm Asano and Fukuyama's conjecture as to the constancy of the beaming for small angles away from the axis; nevertheless, we find the dominant contribution to the MDR comes from near the surface of the disk ...

  9. Eight Pulse Performance of DARHT Axis II - Preliminary Results

    Energy Technology Data Exchange (ETDEWEB)

    Schulze, Martin E. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-12-08

    The DARHT-II accelerator produces a 1.65-kA, 17-MeV beam in a 1600-ns pulse. Standard operation of the DARHT Axis II accelerator involves extracting four short pulses from the 1.6 us long macro-pulse produced by the LIA. The four short pulses are extracted using a fast kicker in combination with a quadrupole septum magnet and then transported for several meters to a high-Z material target for conversion to x-rays for radiography. The ability of the DARHT Axis 2 kicker to produce more than the standard four pulse format has been previously demonstrated. This capability was developed to study potential risks associated with beam transport during an initial commissioning phase at low energy (8 MeV) and low current (1.0 kA).The ability of the kicker to deliver more than four pulses to the target has been realized for many years. This note describes the initial results demonstrating this capability.

  10. Off-axis self-interference incoherent digital holographic microscopy

    Science.gov (United States)

    Jeon, Philjun; Lee, Heejung; So, Byunghwy; Hwang, Wonsang; Bae, Yoonsung; Kim, Dugyoung

    2017-03-01

    3D imaging is demanding technology required in fluorescence microscopy. Even though holography is a powerful technique, it could not be used easily in fluorescence microscopy because of low coherence of fluorescence light. Lately, several incoherent holographic methods such as scanning holography, Fresnel in coherent correlation holography (FINCH), and self-interference incoherent digital holography (SIDH) have been proposed. However, these methods have many problems to be overcome for practical applications. For example, DC term removal, twin image ambiguity, and phase unwrapping problems need to be resolved. Off-axis holography is a straightforward solution which can solve most of these problems. We built an off-axis SIDH system for fluorescence imaging, and investigated various conditions and requirements for practical holographic fluorescence microscopy. Our system is based on a modified Michelson interferometer with a flat mirror at one arm and a curved mirror at the other arm of the interferometer. We made a phantom 3D fluorescence object made of 2 single-mode fibers coupled to a single red LED source to mimic 2 fluorescence point sources distributed by a few tens of micrometers apart. A cooled EM-CCD was used to take holograms of these fiber ends which emit only around 180 nW power.

  11. Optimization of blade motion of vertical axis turbine

    Science.gov (United States)

    Ma, Yong; Zhang, Liang; Zhang, Zhi-yang; Han, Duan-feng

    2016-04-01

    In this paper, a method is proposed to improve the energy efficiency of the vertical axis turbine. First of all, a single disk multiple stream-tube model is used to calculate individual fitness. Genetic algorithm is adopted to optimize blade pitch motion of vertical axis turbine with the maximum energy efficiency being selected as the optimization objective. Then, a particular data processing method is proposed, fitting the result data into a cosine-like curve. After that, a general formula calculating the blade motion is developed. Finally, CFD simulation is used to validate the blade pitch motion formula. The results show that the turbine's energy efficiency becomes higher after the optimization of blade pitch motion; compared with the fixed pitch turbine, the efficiency of variable-pitch turbine is significantly improved by the active blade pitch control; the energy efficiency declines gradually with the growth of speed ratio; besides, compactness has lager effect on the blade motion while the number of blades has little effect on it.

  12. Searching for Cosmological Preferred Axis using cosmographic approach

    CERN Document Server

    Salehi, Amin

    2016-01-01

    Recent released Planck data and other astronomical observations show that the universe may be anisotropic on large scales. This hints a cosmological privileged axis in our anisotropic expanding universe. This paper proceeds a modified redshift in anisotropic cosmological model as $ 1+\\tilde{z}(t,\\hat{\\textbf{p}})=\\frac{a(t_{0)}}{a(t)}(1-A(\\hat{\\textbf{n}}.\\hat{\\textbf{p}}))$ (where $A$ is the magnitude of anisotropy ,$\\hat{\\textbf{n}}$ is the direction of privileged axis, and $\\hat{\\textbf{p}}$ is the direction of each SNe Ia sample to galactic coordinates) along with anisotropic parameter $\\delta=\\frac{A(\\hat{\\textbf{n}}.\\hat{\\textbf{p}})}{1+A(\\hat{\\textbf{n}}.\\hat{\\textbf{p}})}$. The luminosity distance is expanded with model-independent cosmographic parameters as a function of modified redshift $\\tilde{z}$. As the transformation matrix $M(n\\times n)$ is obtained to convert the Taylor series coefficients of isotropic luminosity distance to corresponding anisotropic parameters. These results culminate the ma...

  13. Preferred axis of CMB parity asymmetry in the masked maps

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, Cheng [State Key Laboratory of Theoretical Physics, Institute of Theoretical Physics, Chinese Academy of Science, Beijing 100190 (China); Zhao, Wen, E-mail: wzhao7@ustc.edu.cn [CAS Key Laboratory for Researches in Galaxies and Cosmology, Department of Astronomy, University of Science and Technology of China, Chinese Academy of Sciences, Hefei, Anhui 230026 (China); Huang, Qing-Guo [State Key Laboratory of Theoretical Physics, Institute of Theoretical Physics, Chinese Academy of Science, Beijing 100190 (China); Santos, Larissa [CAS Key Laboratory for Researches in Galaxies and Cosmology, Department of Astronomy, University of Science and Technology of China, Chinese Academy of Sciences, Hefei, Anhui 230026 (China)

    2016-06-10

    Both WMAP and Planck data show a significant odd-multipole preference in the large scales of the cosmic microwave background (CMB) temperature anisotropies. If this pattern originates from cosmological effects, then it can be considered a crucial clue for a violation in the cosmological principle. By defining various direction dependent statistics in the full-sky Planck 2015 maps (see, for instance, Naselsky et al. (2012); W. Zhao (2014)), we found that the CMB parity asymmetry has a preferred direction, which is independent of the choices of the statistics. In particular, this preferred axis is strongly aligned with those in the CMB quadrupole and octopole, as well as that in the CMB kinematic dipole, which hints to their non-cosmological origin. In realistic observations, the foreground residuals are inevitable, and should be properly masked out in order to avoid possible misinterpretation of the results. In this paper, we extend our previous analyses to the masked Planck 2015 data. By defining a similar direction dependent statistic in the masked map, we find a preferred direction of the CMB parity asymmetry, in which the axis also coincides with that found in the full-sky analysis. Therefore, our conclusions on the CMB parity violation and its directional properties are confirmed.

  14. Pituitary-Adrenal Axis in Prader Willi Syndrome

    Directory of Open Access Journals (Sweden)

    Olivia S. Edgar

    2016-01-01

    Full Text Available Purpose: Prader Willi syndrome (PWS is a rare genetic condition that has concurrent endocrinological insufficiencies. The presence of growth hormone deficiency has been well documented, but adrenal insufficiency (AI is not widely reported. A review was conducted to investigate its prevalence and relevance in PWS in both adults and children. Methodology: A literature review was performed with the search terms “Prader-Willi syndrome” and “adrenal insufficiency”. Results: The review found studies disagree on the prevalence and method of investigation of AI in PWS. Case studies demonstrate that patients with PWS are at risk of premature death, often secondary to respiratory infections. The possibility that this may be the result of the inability to mount an effective cortisol response has been studied, with some evidence confirming AI in PWS patients. Most reports agreed AI is present in PWS, however, Farholt et al. showed no HPA axis dysfunction in adults, suggesting that perhaps it is rare in adults, and children should be the focus of further studies. Conclusion: AI is present in some patients with PWS. Further research is required to ensure optimal treatment can be implemented and to prevent premature deaths related to adrenal insufficiency. Clinicians should have a low threshold for testing the adrenal axis and considering treatment for adrenal insufficiency in PWS patients.

  15. Reframing the Teenage Wasteland: Adolescent Microbiota-Gut-Brain Axis.

    Science.gov (United States)

    McVey Neufeld, Karen-Anne; Luczynski, Pauline; Dinan, Timothy G; Cryan, John F

    2016-04-01

    Human adolescence is arguably one of the most challenging periods of development. The young adult is exposed to a variety of stressors and environmental stimuli on a backdrop of significant physiological change and development, which is especially apparent in the brain. It is therefore unsurprising that many psychiatric disorders are first observable during this time. The human intestine is inhabited by trillions of microorganisms, and evidence from both preclinical and clinical research focusing on the established microbiota-gut-brain axis suggests that the etiology and pathophysiology of psychiatric disorders may be influenced by intestinal dysbiosis. Provocatively, many if not all of the challenges faced by the developing teen have a documented impact on these intestinal commensal microbiota. In this review, we briefly summarize what is known about the developing adolescent brain and intestinal microbiota, discuss recent research investigating the microbiota-gut-brain axis during puberty, and propose that pre- and probiotics may prove useful in both the prevention and treatment of psychiatric disorders specifically benefitting the young adult.

  16. Determining the axis orientation of cylindrical magnetic flux rope

    Science.gov (United States)

    Rong, Zhaojin; Wan, Weixing; Shen, Chao; Zhang, Tielong; Lui, Anthony; Wang, Yuming; Dunlop, malcolm; Zhang, Yongcun; Zong, Qiugang

    2013-04-01

    We develop a new simple method for inferring the orientation of a magnetic flux rope, which is assumed to be a time-independent cylindrically symmetric structure via the direct single-point analysis of magnetic field structure. The model tests demonstrate that, for the cylindrical flux rope regardless of whether it is force-free or not, the method can consistently yield the axis orientation of the flux rope with higher accuracy and stability than the minimum variance analysis of the magnetic field and the Grad-Shafranov reconstruction technique. Moreover, the radial distance to the axis center and the current density can also be estimated consistently. Application to two actual flux transfer events observed by the four satellites of the Cluster mission demonstrates that the method is more appropriate to be used for the inner part of flux rope, which might be closer to the cylindrical structure, showing good agreement with the results obtained from the optimal Grad-Shafranov reconstruction and the least squares technique of Faraday's law, but fails to produce such agreement for the outer satellite that grazes the flux rope. Therefore, the method must be used with caution.

  17. Computational analysis of vertical axis wind turbine arrays

    Science.gov (United States)

    Bremseth, J.; Duraisamy, K.

    2016-10-01

    Canonical problems involving single, pairs, and arrays of vertical axis wind turbines (VAWTs) are investigated numerically with the objective of understanding the underlying flow structures and their implications on energy production. Experimental studies by Dabiri (J Renew Sustain Energy 3, 2011) suggest that VAWTs demand less stringent spacing requirements than their horizontal axis counterparts and additional benefits may be obtained by optimizing the placement and rotational direction of VAWTs. The flowfield of pairs of co-/counter-rotating VAWTs shows some similarities with pairs of cylinders in terms of wake structure and vortex shedding. When multiple VAWTs are placed in a column, the extent of the wake is seen to spread further downstream, irrespective of the direction of rotation of individual turbines. However, the aerodynamic interference between turbines gives rise to regions of excess momentum between the turbines which lead to significant power augmentations. Studies of VAWTs arranged in multiple columns show that the downstream columns can actually be more efficient than the leading column, a proposition that could lead to radical improvements in wind farm productivity.

  18. CFD Simulation of Twin Vertical Axis Tidal Turbines System

    Directory of Open Access Journals (Sweden)

    Syed Shah Khalid

    2013-01-01

    Full Text Available As concerns about rising fossil-fuel prices, energy security and climate-change increase, renewable energy can play a vital role in producing local, clean and inexhaustible energy to supply world rising demand for electricity. In this study, hydrodynamic analysis of vertical axis tidal turbine operating side-by-side is numerically analyzed. Two-dimensional numerical modeling of the unsteady flow through the blades of the turbine is performed using ANSYS CFX, hereafter CFX; this is based on a Reynolds-Averaged Navier-Stokes (RANS model. The purpose is to find an optimal distance between the turbines where interaction effect is minimal and constructive, where the turbines operate more efficiently than stand alone turbine. A transient simulation is done on Vertical Axis Tidal Turbine (VATT using the Shear Stress Transport Turbulence (SST model. Main hydrodynamic parameters like torque T, coefficients of performance CP and coefficient of torque CT are investigated. The gap spacing between the turbines has an important role in performance improvement and also in vortex shedding suppression for the flows around two counters rotating systems. The simulation results are validated with Ye and Calisal data. The results of this study prove that the total power output of a twin-turbine system with an optimal layout can be about 24% higher than two times that of a stand-alone turbine. We conclude that the optimally configured counter-rotating twin turbines should be a side-by-side arrangement.

  19. Two Axis Pointing System (TAPS) attitude acquisition, determination, and control

    Science.gov (United States)

    Azzolini, John D.; McGlew, David E.

    1990-12-01

    The Two Axis Pointing System (TAPS) is a 2 axis gimbal system designed to provide fine pointing of Space Transportation System (STS) borne instruments. It features center-of-mass instrument mounting and will accommodate instruments of up to 1134 kg (2500 pounds) which fit within a 1.0 by 1.0 by 4.2 meter (40 by 40 by 166 inch) envelope. The TAPS system is controlled by a microcomputer based Control Electronics Assembly (CEA), a Power Distribution Unit (PDU), and a Servo Control Unit (SCU). A DRIRU-II inertial reference unit is used to provide incremental angles for attitude propagation. A Ball Brothers STRAP star tracker is used for attitude acquisition and update. The theory of the TAPS attitude determination and error computation for the Broad Band X-ray Telescope (BBXRT) are described. The attitude acquisition is based upon a 2 star geometric solution. The acquisition theory and quaternion algebra are presented. The attitude control combines classical position, integral and derivative (PID) control with techniques to compensate for coulomb friction (bias torque) and the cable harness crossing the gimbals (spring torque). Also presented is a technique for an adaptive bias torque compensation which adjusts to an ever changing frictional torque environment. The control stability margins are detailed, with the predicted pointing performance, based upon simulation studies. The TAPS user interface, which provides high level operations commands to facilitate science observations, is outlined.

  20. Optimization of Blade Motion of Vertical Axis Turbine

    Institute of Scientific and Technical Information of China (English)

    马勇; 张亮; 张之阳; 韩端锋

    2016-01-01

    In this paper, a method is proposed to improve the energy efficiency of the vertical axis turbine. First of all, a single disk multiple stream-tube model is used to calculate individual fitness. Genetic algorithm is adopted to optimize blade pitch motion of vertical axis turbine with the maximum energy efficiency being selected as the optimization objective. Then, a particular data processing method is proposed, fitting the result data into a cosine-like curve. After that, a general formula calculating the blade motion is developed. Finally, CFD simulation is used to validate the blade pitch motion formula. The results show that the turbine’s energy efficiency becomes higher after the optimization of blade pitch motion; compared with the fixed pitch turbine, the efficiency of variable-pitch turbine is significantly improved by the active blade pitch control; the energy efficiency declines gradually with the growth of speed ratio; besides, compactness has lager effect on the blade motion while the number of blades has little effect on it.

  1. Related Axis: The Extension to XPath Towards Effective XML Search

    Institute of Scientific and Technical Information of China (English)

    Jun-Feng Zhou; Tok Wang Ling; Zhi-Feng Bao; Xiao-Feng Meng

    2012-01-01

    We investigate the limitations of existing XML search methods and propose a new semantics,related relationship,to effectively capture meaningful relationships of data elements from XML data in the absence of structural constraints.Then we make an extension to XPath by introducing a new axis,related axis,to specify the related relationship between query nodes so as to enhance the flexibility of XPath.We propose to reduce the cost of computing the related relationship by a new schema summary that summarizes the related relationship from the original schema without any loss.Based on this schema summary,we introduce two indices to improve the performance of query processing.Our algorithm shows that the evaluation of most queries can be equivalently transformed into just a few selection and value join operations,thus avoids the costly structural join operations.The experimental results show that our method is effective and efficient in terms of comparing the effectiveness of the related relationship with existing keyword search semantics and comparing the efficiency of our evaluation methods with existing query engines.

  2. Early calibration of the HPA axis by maternal psychopathology.

    Science.gov (United States)

    Laurent, Heidemarie

    2017-02-01

    Given the central role of stress-responsive neurophysiology in mental and physical health, it is important to understand how particular patterns of stress responsivity may become entrained by the early caregiving environment. In this study we investigated links between maternal depression and anxiety symptom profiles and within-infant development of hypothalamic-pituitary-adrenal (HPA) axis responses from 6 to 18 months of life. Associations with infant cognitive and social-emotional development were also tested to gauge the adjustment implications of HPA response trajectories. Mothers from a low-income community sample reported their symptoms at 3, 6, 12, and 18 months postnatal, and infants engaged in interpersonal stress tasks at 6, 12, and 18 months. Four saliva samples were taken at each time to assess cortisol responses, and a developmental screener at 18 months provided an index of infant adjustment. Multilevel modeling results revealed an association between maternal symptoms and infant HPA axis sensitization-i.e., a higher cortisol reactivity slope that increased over time. In particular, early (3-month) depression symptoms among mothers who had crossed a diagnostic threshold for major depressive disorder predicted this pattern of response, which in turn related to poorer infant developmental outcomes. Results are considered in terms of adaptive calibration of stress response systems, which may come at a cost to individual psychosocial functioning.

  3. Shock margin testing of a one-axis MEMS accelerometer.

    Energy Technology Data Exchange (ETDEWEB)

    Parson, Ted Blair; Tanner, Danelle Mary; Buchheit, Thomas Edward

    2008-07-01

    Shock testing was performed on a selected commercial-off-the-shelf - MicroElectroMechanical System (COTS-MEMS) accelerometer to determine the margin between the published absolute maximum rating for shock and the 'measured' level where failures are observed. The purpose of this testing is to provide baseline data for isolating failure mechanisms under shock and environmental loading in a representative device used or under consideration for use within systems and assemblies of the DOD/DOE weapons complex. The specific device chosen for this study was the AD22280 model of the ADXL78 MEMS Accelerometer manufactured by Analog Devices Inc. This study focuses only on the shock loading response of the device and provides the necessary data for adding influence of environmental exposure to the reliability of this class of devices. The published absolute maximum rating for acceleration in any axis was 4000 G for this device powered or unpowered. Results from this study showed first failures at 8000 G indicating a margin of error of two. Higher shock level testing indicated that an in-plane, but off-axis acceleration was more damaging than one in the sense direction.

  4. Actuator line modeling of vertical-axis turbines

    CERN Document Server

    Bachant, Peter; Wosnik, Martin

    2016-01-01

    To bridge the gap between high and low fidelity numerical modeling tools for vertical-axis (or cross-flow) turbines (VATs or CFTs), an actuator line model (ALM) was developed and validated for both a high and a medium solidity vertical-axis turbine at rotor diameter Reynolds numbers $Re_D \\sim 10^6$. The ALM is a hybridization of classical blade element theory with Navier--Stokes based flow models, and in this study both $k$--$\\epsilon$ Reynolds-averaged Navier--Stokes (RANS) and Smagorinsky large eddy simulation (LES) turbulence models were tested. The RANS models were able to be run on coarse grids while still providing good convergence behavior in terms of the mean power coefficient, and also approximately four orders of magnitude reduction in computational expense compared with 3-D blade-resolved RANS simulations. Submodels for dynamic stall, end effects, added mass, and flow curvature were implemented, resulting in reasonable performance predictions for the high solidity rotor, more discrepancies for the...

  5. On the spin-axis dynamics of a Moonless Earth

    Energy Technology Data Exchange (ETDEWEB)

    Li, Gongjie; Batygin, Konstantin, E-mail: gli@cfa.harvard.edu [Harvard-Smithsonian Center for Astrophysics, The Institute for Theory and Computation, 60 Garden Street, Cambridge, MA 02138 (United States)

    2014-07-20

    The variation of a planet's obliquity is influenced by the existence of satellites with a high mass ratio. For instance, Earth's obliquity is stabilized by the Moon and would undergo chaotic variations in the Moon's absence. In turn, such variations can lead to large-scale changes in the atmospheric circulation, rendering spin-axis dynamics a central issue for understanding climate. The relevant quantity for dynamically forced climate change is the rate of chaotic diffusion. Accordingly, here we re-examine the spin-axis evolution of a Moonless Earth within the context of a simplified perturbative framework. We present analytical estimates of the characteristic Lyapunov coefficient as well as the chaotic diffusion rate and demonstrate that even in absence of the Moon, the stochastic change in Earth's obliquity is sufficiently slow to not preclude long-term habitability. Our calculations are consistent with published numerical experiments and illustrate the putative system's underlying dynamical structure in a simple and intuitive manner.

  6. PRIGo: a new multi-axis goniometer for macromolecular crystallography

    Energy Technology Data Exchange (ETDEWEB)

    Waltersperger, Sandro; Olieric, Vincent, E-mail: vincent.olieric@psi.ch; Pradervand, Claude [Paul Scherrer Institute, Villigen PSI (Switzerland); Glettig, Wayne [Centre Suisse d’Electronique et Microtechnique SA, Neuchâtel 2002 (Switzerland); Salathe, Marco; Fuchs, Martin R.; Curtin, Adrian; Wang, Xiaoqiang; Ebner, Simon; Panepucci, Ezequiel; Weinert, Tobias [Paul Scherrer Institute, Villigen PSI (Switzerland); Schulze-Briese, Clemens [Dectris Ltd, Baden 5400 (Switzerland); Wang, Meitian, E-mail: vincent.olieric@psi.ch [Paul Scherrer Institute, Villigen PSI (Switzerland)

    2015-05-09

    The design and performance of the new multi-axis goniometer PRIGo developed at the Swiss Light Source at Paul Scherrer Institute is described. The Parallel Robotics Inspired Goniometer (PRIGo) is a novel compact and high-precision goniometer providing an alternative to (mini-)kappa, traditional three-circle goniometers and Eulerian cradles used for sample reorientation in macromolecular crystallography. Based on a combination of serial and parallel kinematics, PRIGo emulates an arc. It is mounted on an air-bearing stage for rotation around ω and consists of four linear positioners working synchronously to achieve x, y, z translations and χ rotation (0–90°), followed by a ϕ stage (0–360°) for rotation around the sample holder axis. Owing to the use of piezo linear positioners and active correction, PRIGo features spheres of confusion of <1 µm, <7 µm and <10 µm for ω, χ and ϕ, respectively, and is therefore very well suited for micro-crystallography. PRIGo enables optimal strategies for both native and experimental phasing crystallographic data collection. Herein, PRIGo hardware and software, its calibration, as well as applications in macromolecular crystallography are described.

  7. Experimental development of a torsion arc blade type horizontal axis windmil; Nejire enko yokugata suihei jiku fusha no kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    Kojima, N. [Meiji Univ., Tokyo (Japan). Faculty of Scince and Technology

    1996-05-31

    To get more wind energy, longer rotating blades and higher towers of windmills are required. Therefore, the location of windmills is limited and the initial cost gets higher. In this study, a small size windmill which can generate electricity even in a city was developed and tested. A torsion arc blade type horizontal axis windmill was designed and the blade form, number and degree of distortion were investigated. Based on the results, a small windmill was made, rotation and generation tests were carried out and it was confirmed that the windmill could be used as a small scale wind power generation. The windmill is of simple construction having 6 arc blades and no high tower is required. This paper consists of 6 sections, i.e. Introduction, Windmill model, Tested windmill, Test facility and method, Test results and consideration, and Postscript. 2 refs., 18 figs., 1 tab.

  8. Fracture fixation of the Odontoid process of the axis through an osseous-axis pin in Cuba. A case report.

    Directory of Open Access Journals (Sweden)

    José Ramón Tejera del Valle

    2005-11-01

    Full Text Available The fractures of the odontoid process of the Axis has been a polemic topic for many years. The alternative technique of placing a fixation screw directly across the fracture site, reattaching the odontoid to the body of C2 had been gained defensors in the actuality in the world. The topic was reviewed, and the seventh case knowned was been operated in Cuba by this technique was presented. This intervention was realized in the Department of Neurosurgery of Cienfuegos. Current considerations are emitted.

  9. Magnetocumulative generator

    Science.gov (United States)

    Pettibone, J.S.; Wheeler, P.C.

    1981-06-08

    An improved magnetocumulative generator is described that is useful for producing magnetic fields of very high energy content over large spatial volumes. The polar directed pleated magnetocumulative generator has a housing providing a housing chamber with an electrically conducting surface. The chamber forms a coaxial system having a small radius portion and a large radius portion. When a magnetic field is injected into the chamber, from an external source, most of the magnetic flux associated therewith positions itself in the small radius portion. The propagation of an explosive detonation through high-explosive layers disposed adjacent to the housing causes a phased closure of the chamber which sweeps most of the magnetic flux into the large radius portion of the coaxial system. The energy content of the magnetic field is greatly increased by flux stretching as well as by flux compression. The energy enhanced magnetic field is utilized within the housing chamber itself.

  10. Idea generation

    DEFF Research Database (Denmark)

    Tollestrup, Christian H. T.; Laursen, Linda Nhu

    2015-01-01

    of an idea generation whether the outset is ill defined and questioned as opposed to straightforward ideation on a proposal for a solution? The hypothesis is that an approach to ideation where ambiguity and discrepancy deliberately is sought creates more radical innovation that an approach without this...... as having new sociocultural meaning in line with Vergantis definition of radical innovation. This paper discusses the results of an experiment with 32 students on idea generation and product concept development. The experiment was setup as and A-B comparison between two set of students with the same...... different solutions when seeking ambiguity and discrepancy. Within the very limited experiment the conclusion seems to be very clear, it leads to more innovation if the designer seeks to question the framing and scope of the task. So seeking ambiguity and discrepancy in the ideation phase aligns...

  11. Six-axis multi-anvil press for high-pressure, high-temperature neutron diffraction experiments.

    Science.gov (United States)

    Sano-Furukawa, A; Hattori, T; Arima, H; Yamada, A; Tabata, S; Kondo, M; Nakamura, A; Kagi, H; Yagi, T

    2014-11-01

    We developed a six-axis multi-anvil press, ATSUHIME, for high-pressure and high-temperature in situ time-of-flight neutron powder diffraction experiments. The press has six orthogonally oriented hydraulic rams that operate individually to compress a cubic sample assembly. Experiments indicate that the press can generate pressures up to 9.3 GPa and temperatures up to 2000 K using a 6-6-type cell assembly, with available sample volume of about 50 mm(3). Using a 6-8-type cell assembly, the available conditions expand to 16 GPa and 1273 K. Because the six-axis press has no guide blocks, there is sufficient space around the sample to use the aperture for diffraction and place an incident slit, radial collimators, and a neutron imaging camera close to the sample. Combination of the six-axis press and the collimation devices realized high-quality diffraction pattern with no contamination from the heater or the sample container surrounding the sample. This press constitutes a new tool for using neutron diffraction to study the structures of crystals and liquids under high pressures and temperatures.

  12. Six-axis multi-anvil press for high-pressure, high-temperature neutron diffraction experiments

    Energy Technology Data Exchange (ETDEWEB)

    Sano-Furukawa, A., E-mail: sano.asami@jaea.go.jp; Hattori, T. [Quantum Beam Science Center, Japan Atomic Energy Agency, Ibaraki 319-1195 (Japan); J-PARC Center, Japan Atomic Energy Agency, Ibaraki 319-1195 (Japan); Arima, H. [Institute for Materials Research, Tohoku University, Sendai 980-8577 (Japan); Yamada, A. [The University of Shiga Prefecture, Shiga 522-8533 (Japan); Tabata, S.; Kondo, M.; Nakamura, A. [Sumitomo Heavy Industries Co., Ltd., Ehime 792-0001 (Japan); Kagi, H.; Yagi, T. [Geochemical Research Center, Graduate School of Science, The University of Tokyo, Tokyo 113-0033 (Japan)

    2014-11-15

    We developed a six-axis multi-anvil press, ATSUHIME, for high-pressure and high-temperature in situ time-of-flight neutron powder diffraction experiments. The press has six orthogonally oriented hydraulic rams that operate individually to compress a cubic sample assembly. Experiments indicate that the press can generate pressures up to 9.3 GPa and temperatures up to 2000 K using a 6-6-type cell assembly, with available sample volume of about 50 mm{sup 3}. Using a 6-8-type cell assembly, the available conditions expand to 16 GPa and 1273 K. Because the six-axis press has no guide blocks, there is sufficient space around the sample to use the aperture for diffraction and place an incident slit, radial collimators, and a neutron imaging camera close to the sample. Combination of the six-axis press and the collimation devices realized high-quality diffraction pattern with no contamination from the heater or the sample container surrounding the sample. This press constitutes a new tool for using neutron diffraction to study the structures of crystals and liquids under high pressures and temperatures.

  13. Impaired hypothalamic-pituitary-testicular axis activity, spermatogenesis, and sperm function promote infertility in males with lead poisoning.

    Science.gov (United States)

    Gandhi, Jason; Hernandez, Rafael J; Chen, Andrew; Smith, Noel L; Sheynkin, Yefim R; Joshi, Gargi; Khan, Sardar Ali

    2017-02-10

    Lead poisoning is a stealthy threat to human physiological systems as chronic exposure can remain asymptomatic for long periods of time before symptoms manifest. We presently review the biophysical mechanisms of lead poisoning that contribute to male infertility. Environmental and occupational exposure of lead may adversely affect the hypothalamic-pituitary-testicular axis, impairing the induction of spermatogenesis. Dysfunction at the reproductive axis, namely testosterone suppression, is most susceptible and irreversible during pubertal development. Lead poisoning also appears to directly impair the process of spermatogenesis itself as well as sperm function. Spermatogenesis issues may manifest as low sperm count and stem from reproductive axis dysfunction or testicular degeneration. Generation of excessive reactive oxygen species due to lead-associated oxidative stress can potentially affect sperm viability, motility, DNA fragmentation, membrane lipid peroxidation, capacitation, hyperactivation, acrosome reaction, and chemotaxis for sperm-oocyte fusion, all of which can contribute to deter fertilization. Reproductive toxicity has been tested through cross-sectional analysis studies in humans as well as in vivo and in vitro studies in animals.

  14. Finding the vertex position using the SPD in stand alone mode and the effects of the off-axis vertexm

    CERN Document Server

    Nilsen, B S; CERN. Geneva; Bustreo, N

    2001-01-01

    The Inner T rac king System (ITS) detector of the Al- ice apparatus giv es a go o d opp ortunit y to determine the v ertex p osition, along the b eam axis (z co ordinate), ev en in the absence of trac king and, therefore, without ev en t reconstruction. This can b e obtained b y using only the information of the t w o Silicon Pixel Detector (SPD) la y ers. In principle it is suÆcien t to lo ok at the correlation b et w een the z- co ordinate of the t w o hits generated, b y the same trac k, in these t w ola y ers. In fact in the plane r-z, where r the distance of the hit from z axis (r= p x 2 + y 2 ), the pro jec- tion of a trac k app ears as a straigh tline. Consequen tly the z-p osition of the v ertex corresp onds to the crossing bet w een this line and the b eam axis if the trac kis due to a primary particle. Ob viously it is not p ossible to distinguish the primary particles from the pro ducts of the secondary deca y with- out ev en t reconstruction. Ho w ev er, the con tribution of the secondary trac ks...

  15. Photon generator

    Science.gov (United States)

    Srinivasan-Rao, Triveni

    2002-01-01

    A photon generator includes an electron gun for emitting an electron beam, a laser for emitting a laser beam, and an interaction ring wherein the laser beam repetitively collides with the electron beam for emitting a high energy photon beam therefrom in the exemplary form of x-rays. The interaction ring is a closed loop, sized and configured for circulating the electron beam with a period substantially equal to the period of the laser beam pulses for effecting repetitive collisions.

  16. Urban Energy Generation and the Role of Cities

    DEFF Research Database (Denmark)

    Groth, Niels Boje; Fertner, Christian; Große, Juliane

    2016-01-01

    into the grid. Furthermore, through the ongoing liberalisation of energy markets and a subsequent change in the organisation structure of energy providers towards larger co-operations as well as the development of new technologies as ‘smart grid’-solutions, local authorities seem to lose further influence...... or continental grid; energy for heating, if related to district heating systems or the use of local/regional resources for its generation (e.g. biomass, waste), has a more local or at least regional character. In the latter case, electricity might be a by-product of combined-heat-power plants, but still feeding...... on energy generation and distribution. However, contemporary focus on sustainable and efficient use of resources and energy at local level, mainstreaming of renewable energy production and ideas of urban energy harvesting put energy generation again on the local agenda. The role of cities can be twofold: (1...

  17. Dual axis translation apparatus and system for translating an optical beam and related method

    Science.gov (United States)

    Cassidy, Kelly

    1991-01-01

    A dual axis translation device and system in accordance with this invention, for translating an optical beam along both an x-axis and a y-axis which are perpendicular to one another, has a beam directing means acting on said optical beam for directing the beam along a particular path transverse to said x and y axes. An arrangement supporting said beam directing means for movement in the x and y direction within a given plane is provided. The arrangement includes a first means for translating said beam directing means along the x-axis in said given plane in order to translate the beam along said x-axis. The arrangement comprises a second means for translating said beam directing means along the y-axis in said given plane in order to translate the beam along said y-axis.

  18. Comparison of Efficiencies of Solar Tracker systems with static panel Single- Axis Tracking System and Dual-Axis Tracking System with Fixed Mount

    Directory of Open Access Journals (Sweden)

    Dhanabal.R

    2013-04-01

    Full Text Available Electricity plays a key role now in our daily lives but the energy sources to electric power has been used in abundance and so researchers were compelled to find an alternate source of power leading to the discovery of solar energy. Solar energy is inexhaustible and eco-friendly and can be converted into electricityusing photovoltaic panels. These panels can be used in a fixed form or used in a solar tracking system for single axis as well as for dual axis. In a fixed form their efficiency is low since the panels will be tilted in a particular angle whereas in a tracking system the panel is made to move either in single axis or dual axis. In a single axis system the panel is moved in an east to west direction with respect to the sun and it has better efficiency than panels in fixed form. But in a dual axis system the panel is made to rotate in all four directions in accordance with the sun. And dual axis has proved to have more efficiency than both fixed panels and single axis system.

  19. On steady rotations of a rigid body bearing a single-axis powered gyroscope whose precession axis is parallel to a principal plane of inertia

    NARCIS (Netherlands)

    Amel'kin, N. I.

    2009-01-01

    The set of steady motions of the system named in the title is represented parametrically via the gyro gimbal rotation angle for an arbitrary position of the gimbal axis. We study the set of steady motions for a system in which the gyro gimbal axis is parallel to a principal plane of inertia as well

  20. Involvement of the hypothalamic-pituitary-thyroid axis and its interaction with the hypothalamic-pituitary-adrenal axis in the ontogeny of avian thermoregulation: a review

    NARCIS (Netherlands)

    Debonne, M.; Baarendse, P.J.J.; Brand, van den H.; Kemp, B.; Bruggeman, V.; Decuypere, E.

    2008-01-01

    The emergence of thermoregulation in avian species is a complex matter in which neural as well as hormonal processes are involved. In a previous paper, the neural aspects of primary avian thermoregulation were discussed. In this paper the role of the hypothalamus-pituitary-thyroid axis (HPT-axis)