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Sample records for two-phase s-p relations

  1. Automatic Detection of P and S Phases by Support Vector Machine

    Science.gov (United States)

    Jiang, Y.; Ning, J.; Bao, T.

    2017-12-01

    Many methods in seismology rely on accurately picked phases. A well performed program on automatically phase picking will assure the application of these methods. Related researches before mostly focus on finding different characteristics between noise and phases, which are all not enough successful. We have developed a new method which mainly based on support vector machine to detect P and S phases. In it, we first input some waveform pieces into the support vector machine, then employ it to work out a hyper plane which can divide the space into two parts: respectively noise and phase. We further use the same method to find a hyper plane which can separate the phase space into P and S parts based on the three components' cross-correlation matrix. In order to further improve the ability of phase detection, we also employ array data. At last, we show that the overall effect of our method is robust by employing both synthetic and real data.

  2. Phase analysis of circadian-related genes in two tissues

    Directory of Open Access Journals (Sweden)

    Li Leping

    2006-02-01

    Full Text Available Abstract Background Recent circadian clock studies using gene expression microarray in two different tissues of mouse have revealed not all circadian-related genes are synchronized in phase or peak expression times across tissues in vivo. Instead, some circadian-related genes may be delayed by 4–8 hrs in peak expression in one tissue relative to the other. These interesting biological observations prompt a statistical question regarding how to distinguish the synchronized genes from genes that are systematically lagged in phase/peak expression time across two tissues. Results We propose a set of techniques from circular statistics to analyze phase angles of circadian-related genes in two tissues. We first estimate the phases of a cycling gene separately in each tissue, which are then used to estimate the paired angular difference of the phase angles of the gene in the two tissues. These differences are modeled as a mixture of two von Mises distributions which enables us to cluster genes into two groups; one group having synchronized transcripts with the same phase in the two tissues, the other containing transcripts with a discrepancy in phase between the two tissues. For each cluster of genes we assess the association of phases across the tissue types using circular-circular regression. We also develop a bootstrap methodology based on a circular-circular regression model to evaluate the improvement in fit provided by allowing two components versus a one-component von-Mises model. Conclusion We applied our proposed methodologies to the circadian-related genes common to heart and liver tissues in Storch et al. 2, and found that an estimated 80% of circadian-related transcripts common to heart and liver tissues were synchronized in phase, and the other 20% of transcripts were lagged about 8 hours in liver relative to heart. The bootstrap p-value for being one cluster is 0.063, which suggests the possibility of two clusters. Our methodologies can

  3. P-T phase diagram of a holographic s+p model from Gauss-Bonnet gravity

    International Nuclear Information System (INIS)

    Nie, Zhang-Yu; Zeng, Hui

    2015-01-01

    In this paper, we study the holographic s+p model in 5-dimensional bulk gravity with the Gauss-Bonnet term. We work in the probe limit and give the Δ-T phase diagrams at three different values of the Gauss-Bonnet coefficient to show the effect of the Gauss-Bonnet term. We also construct the P-T phase diagrams for the holographic system using two different definitions of the pressure and compare the results.

  4. Two-Phase Equilibrium Properties in Charged Topological Dilaton AdS Black Holes

    Directory of Open Access Journals (Sweden)

    Hui-Hua Zhao

    2016-01-01

    Full Text Available We discuss phase transition of the charged topological dilaton AdS black holes by Maxwell equal area law. The two phases involved in the phase transition could coexist and we depict the coexistence region in P-v diagrams. The two-phase equilibrium curves in P-T diagrams are plotted, the Clapeyron equation for the black hole is derived, and the latent heat of isothermal phase transition is investigated. We also analyze the parameters of the black hole that could have an effect on the two-phase coexistence. The results show that the black holes may go through a small-large phase transition similar to that of a usual nongravity thermodynamic system.

  5. Non-local two phase flow momentum transport in S BWR

    International Nuclear Information System (INIS)

    Espinosa P, G.; Salinas M, L.; Vazquez R, A.

    2015-09-01

    The non-local momentum transport equations derived in this work contain new terms related with non-local transport effects due to accumulation, convection, diffusion and transport properties for two-phase flow. For instance, they can be applied in the boundary between a two-phase flow and a solid phase, or in the boundary of the transition region of two-phase flows where the local volume averaging equations fail. The S BWR was considered to study the non-local effects on the two-phase flow thermal-hydraulic core performance in steady-state, and the results were compared with the classical local averaging volume conservation equations. (Author)

  6. Non-local two phase flow momentum transport in S BWR

    Energy Technology Data Exchange (ETDEWEB)

    Espinosa P, G.; Salinas M, L.; Vazquez R, A., E-mail: gepe@xanum.uam.mx [Universidad Autonoma Metropolitana, Unidad Iztapalapa, Area de Ingenieria en Recursos Energeticos, Apdo. Postal 55-535, 09340 Ciudad de Mexico (Mexico)

    2015-09-15

    The non-local momentum transport equations derived in this work contain new terms related with non-local transport effects due to accumulation, convection, diffusion and transport properties for two-phase flow. For instance, they can be applied in the boundary between a two-phase flow and a solid phase, or in the boundary of the transition region of two-phase flows where the local volume averaging equations fail. The S BWR was considered to study the non-local effects on the two-phase flow thermal-hydraulic core performance in steady-state, and the results were compared with the classical local averaging volume conservation equations. (Author)

  7. Automatic picking of direct P, S seismic phases and fault zone head waves

    Science.gov (United States)

    Ross, Z. E.; Ben-Zion, Y.

    2014-10-01

    We develop a set of algorithms for automatic detection and picking of direct P and S waves, as well as fault zone head waves (FZHW), generated by earthquakes on faults that separate different lithologies and recorded by local seismic networks. The S-wave picks are performed using polarization analysis and related filters to remove P-wave energy from the seismograms, and utilize STA/LTA and kurtosis detectors in tandem to lock on the phase arrival. The early portions of P waveforms are processed with STA/LTA, kurtosis and skewness detectors for possible first-arriving FZHW. Identification and picking of direct P and FZHW is performed by a multistage algorithm that accounts for basic characteristics (motion polarities, time difference, sharpness and amplitudes) of the two phases. The algorithm is shown to perform well on synthetic seismograms produced by a model with a velocity contrast across the fault, and observed data generated by earthquakes along the Parkfield section of the San Andreas fault and the Hayward fault. The developed techniques can be used for systematic processing of large seismic waveform data sets recorded near major faults.

  8. Development of a Long-Column Method to Test Constitutive Relations for LNAPL Movement in Two-Phase Systems

    Science.gov (United States)

    Oostrom, M.; Zhong, L.; Wietsma, T.; Covert, M.

    2007-12-01

    Multifluid relative permeability - saturation - capillary pressure (k-S-P) empirical constitutive models are components of numerical simulators that are used to predict fluid distributions following a nonaqueous phase liquid (NAPL) contamination event or during remediation. The S-P parameter values for these empirical models are either obtained from the literature or determined experimentally by fitting the models to measured data. Most of the experimental emphasis so far has been on testing the S-P component of the k-S-P constitutive relations. Due to the difficulties in obtaining quality relative permeability laboratory data for multiphase systems, testing of the k-S models that are used in multifluid flow simulators has been virtually non-existent. A new tool, the Multiple Location Saturation Pressure Apparatus (MLSPA), located in PNNL's EMSL Subsurface Flow and Transport Laboratory, has been developed to obtain data sets that can be used to test both S-P and k-S relationships for two-phase NAPL-water systems. The MLSPA is a long column (~1 m) equipped with several hydrophilic and hydrophobic pressure transducers. Fluid saturations are determined along the length of a column using a dual-energy gamma radiation system. Although the MLSPA is limited to porous media with a relatively small entry pressure and fairly homogeneous pore-size distributions, it offers the distinct advantage of obtaining S-P data at multiple locations. Besides for static determinations of S-P relations, the MLSPA offers the benefit that it can be used for more dynamic experiments where fluid pressures are changed more rapidly. The data sets produced by the dynamic experiments can be used in relative permeability models. Results of several experiments with crude-oil brine systems will be presented.

  9. Mechanism of Formation of Li 7 P 3 S 11 Solid Electrolytes through Liquid Phase Synthesis

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Yuxing [Energy; Lu, Dongping [Energy; Bowden, Mark [Environmental; El Khoury, Patrick Z. [Environmental; Han, Kee Sung [Environmental; Deng, Zhiqun Daniel [Energy; Xiao, Jie [Energy; Zhang, Ji-Guang [Energy; Liu, Jun [Energy

    2018-01-22

    Crystalline Li7P3S11 is a promising solid electrolyte for all solid state lithium/lithium ion batteries. A controllable liquid phase synthesis of Li7P3S11 is more desirable compared to conventional mechanochemical synthesis, but recent attempts suffer from reduced ionic conductivities. Here we elucidate the formation mechanism of crystalline Li7P3S11 synthesized in the liquid phase (acetonitrile, or ACN). We conclude that the crystalline Li7P3S11 forms through a two-step reaction: 1) formation of solid Li3PS4∙ACN and amorphous Li2S∙P2S5 phases in the liquid phase; 2) solid-state conversion of the two phases. The implication of this two-step reaction mechanism to the morphology control and the transport properties of liquid phase synthesized Li7P3S11 is identified and discussed.

  10. Transient two-phase flow

    International Nuclear Information System (INIS)

    Hsu, Y.Y.

    1974-01-01

    The following papers related to two-phase flow are summarized: current assumptions made in two-phase flow modeling; two-phase unsteady blowdown from pipes, flow pattern in Laval nozzle and two-phase flow dynamics; dependence of radial heat and momentum diffusion; transient behavior of the liquid film around the expanding gas slug in a vertical tube; flooding phenomena in BWR fuel bundles; and transient effects in bubble two-phase flow. (U.S.)

  11. Phase diagram of ZnCr2pA12-2pS(Se)4 and Zn1-pCdpCr2S(Se)4

    International Nuclear Information System (INIS)

    Afif, K.; Benyoussef, A.; Hamedoun, M.; Hourmatallah, A.

    1999-06-01

    We compute the phase diagram of the nonmetallic compounds ZnCr2 p A1 2-2p S(Se) 4 (I[S,Se]) and Zn 1-p Cd p Cr 2 S(Se) 4 (II[S,Se]). We consider the bond-diluted Ising model on the spinel B site (S.B.S.) lattice with competitive exchange interactions, i.e. the ferromagnetic exchange interaction J 1 between nearest neighbours (n.n.) and the antiferromagnetic superexchange interaction J 2 between next-nearest neighbours' (n.n.n.) (and/or the more distant superexchange interactions J i (i > 1). Dilution and competition are found to be responsible for the spill glass phase and the percolation behaviour. (author)

  12. Phosphoinositide-3-kinases p110alpha and p110beta mediate S phase entry in astroglial cells in the marginal zone of rat neocortex

    Directory of Open Access Journals (Sweden)

    Rabea eMüller

    2013-03-01

    Full Text Available In cells cultured from neocortex of newborn rats, phosphoinositide-3-kinases of class I regulate the DNA synthesis in a subgroup of astroglial cells. We have studied the location of these cells as well as the kinase isoforms which facilitate the S phase entry. Using dominant negative isoforms as well as selective pharmacological inhibitors we quantified S phase entry by nuclear labeling with bromodeoxyuridine. Only in astroglial cells harvested from the marginal zone of the neocortex inhibition of phosphoinositide-3-kinases reduced the nuclear labeling with bromodeoxyuridine, indicating that neocortical astroglial cells differ in the regulation of proliferation. The two kinase isoforms p110 and p110were essential for S phase entry. p110 diminished the level of the p27Kip1 which inactivates the complex of cyclin E and CDK2 necessary for entry into the S phase. p110phosphorylated and inhibited glycogen synthase kinase-3which can prevent S-phase entry. Taken together, both isoforms mediated S phase in a subgroup of neocortical astroglial cells and acted via distinct pathways.

  13. Linking photochemistry in the gas and solution phase: S-H bond fission in p-methylthiophenol following UV photoexcitation.

    Science.gov (United States)

    Oliver, Thomas A A; Zhang, Yuyuan; Ashfold, Michael N R; Bradforth, Stephen E

    2011-01-01

    Gas-phase H (Rydberg) atom photofragment translational spectroscopy and solution-phase femtosecond-pump dispersed-probe transient absorption techniques are applied to explore the excited state dynamics of p-methylthiophenol connecting the short time reactive dynamics in the two phases. The molecule is excited at a range of UV wavelengths from 286 to 193 nm. The experiments clearly demonstrate that photoexcitation results in S-H bond fission--both in the gas phase and in ethanol solution-and that the resulting p-methythiophenoxyl radical fragments are formed with significant vibrational excitation. In the gas phase, the recoil anisotropy of the H atom and the vibrational energy disposal in the p-MePhS radical products formed at the longer excitation wavelengths reveal the operation of two excited state dissociation mechanisms. The prompt excited state dissociation motif appears to map into the condensed phase also. In both phases, radicals are produced in both their ground and first excited electronic states; characteristic signatures for both sets of radical products are already apparent in the condensed phase studies after 50 fs. No evidence is seen for either solute ionisation or proton coupled electron transfer--two alternate mechanisms that have been proposed for similar heteroaromatics in solution. Therefore, at least for prompt S-H bond fissions, the direct observation of the dissociation process in solution confirms that the gas phase photofragmentation studies indeed provide important insights into the early time dynamics that transfer to the condensed phase.

  14. Dynamic interaction of p220NPAT and CBP/p300 promotes S-phase entry

    International Nuclear Information System (INIS)

    Wang, Aiyan; Ikura, Tsuyoshi; Eto, Kazuhiro; Ota, Masato S.

    2004-01-01

    Cajal bodies contain cyclin E/cdk2 and the substrate p220 NPAT to regulate the transcription of histones, which is essential for cell proliferation, however, recent mouse knockout studies indicate that cyclin E and cdk2 are dispensable for these events. Because the CBP/p300 histone acetyltransferase are also known to be involved in cell proliferation, we examined the molecular and functional interactions of p220 NPAT with the CBP/p300 at the G1/S boundary as cell cycle regulators. The subnuclear localization of p220 NPAT and CBP/p300 proteins showed that their foci partially overlapped in a cell cycle dependent manner. Overexpression of p220 NPAT and CBP/p300 cooperatively enhanced G1/S transition and DNA synthesis even without cdk2 phosphorylation site. Finally, molecular alignment analysis indicated that p220 NPAT contains several potential substrate sites for CBP/p300. Overall, our findings demonstrate that p220 NPAT and CBP/p300 form a transient complex at the G1/S boundary to play cooperative roles to promote the S-phase entry

  15. Aqueous phase transfer of InP/ZnS nanocrystals conserving fluorescence and high colloidal stability.

    Science.gov (United States)

    Tamang, Sudarsan; Beaune, Grégory; Texier, Isabelle; Reiss, Peter

    2011-12-27

    Small thiol-containing amino acids such as cysteine are appealing surface ligands for transferring semiconductor quantum dots (QDs) from organic solvents to the aqueous phase. They provide a compact hydrodynamic diameter and low nonspecific binding in biological environment. However, cysteine-capped QDs generally exhibit modest colloidal stability in water and their fluorescence quantum yield (QY) is significantly reduced as compared to organics. We demonstrate that during phase transfer the deprotonation of the thiol group by carefully adjusting the pH is of crucial importance for increasing the binding strength of cysteine to the QD surface. As a result, the colloidal stability of cysteine-capped InP/ZnS core/shell QDs is extended from less than one day to several months. The developed method is of very general character and can be used also with other hydrophilic thiols and various other types of QDs, e.g., CdSe/CdS/ZnS and CuInS(2)/ZnS QDs as well as CdSe and CdSe/CdS nanorods. We show that the observed decrease of QY upon phase transfer with cysteine is related to the generation of cysteine dimer, cystine. This side-reaction implies the formation of disulfide bonds, which efficiently trap photogenerated holes and inhibit radiative recombination. On the other hand, this process is not irreversible. By addition of an appropriate reducing agent, tris(2-carboxyethyl)phosphine hydrochloride (TCEP), the QY can be partially recovered. When TCEP is already added during the phase transfer, the QY of cysteine-capped InP/ZnS QDs can be maintained almost quantitatively. Finally, we show that penicillamine is a promising alternative to cysteine for the phase transfer of QDs, as it is much less prone to disulfide formation.

  16. The two-dimensional thiophosphate CsCrP2S7

    Directory of Open Access Journals (Sweden)

    Kyounghee Kim

    2010-09-01

    Full Text Available The quaternary title compound, caesium chromium(III heptathiodiphosphate(V, CsCrP2S7, has been synthesized using the reactive halide flux method. It is isotypic with other AMP2S7 (A = alkali metal; M = Cr, V or In structures and consists of two-dimensional ∞2[CrP2S7]− layers extending parallel to (001 which are separated from each other by Cs+ ions (symmetry 2. The layer is built up from slightly distorted octahedral [CrS6] units (symmetry 2 and bent [P2S7] units consisting of two corner-sharing [PS4] tetrahedra. The [CrS6] octahedra share two edges and two corners with the [PS4] tetrahedra. There are only van der Waals interactions present between the layers. The Cs+ ions are located in this van der Waals gap and stabilize the structure through weak ionic interactions. The classical charge balance of the title compound can be expressed as [Cs+][Cr3+][P5+]2[S2−]7.

  17. Differential S-phase progression after irradiation of p53 functional versus non-functional tumour cells

    Directory of Open Access Journals (Sweden)

    Zölzer Friedo

    2014-12-01

    Full Text Available Background. Many pathways seem to be involved in the regulation of the intra-S-phase checkpoint after exposure to ionizing radiation, but the role of p53 has proven to be rather elusive. Here we have a closer look at the progression of irradiated cells through S-phase in dependence of their p53 status.

  18. Attosecond relative delay among xenon 5p, 5s, and 4d photoionization

    Science.gov (United States)

    Magrakvelidze, Maia; Madjet, Mohamed; Chakraborty, Himadri

    2017-04-01

    Attosecond Wigner-Smith (WS) time delays of the photoemissions of Xe valence 5p, 5s, and core 4d electrons are investigated in details using the time-dependent local density approximation (TDLDA). Electron correlations determine the energy-dependent structures in ionization phases of the dipole channels and in the resulting WS delays at various shape resonances, induced by the collective motion of 4d electrons, and at various Cooper minima. We find that our calculation closely agrees with the streaking measurement for the delay of 4d relative to 5s, and predicts accelerated emission of 5p with respect to 4d as was experimentally observed at similar photon energies for Xe atoms adsorbed on the tungsten surface. This work was supported by the U.S. National Science Foundation.

  19. Some issues in the simulation of two-phase flows: The relative velocity

    International Nuclear Information System (INIS)

    Gräbel, J.; Hensel, S.; Ueberholz, P.; Farber, P.; Zeidan, D.

    2016-01-01

    In this paper we compare numerical approximations for solving the Riemann problem for a hyperbolic two-phase flow model in two-dimensional space. The model is based on mixture parameters of state where the relative velocity between the two-phase systems is taken into account. This relative velocity appears as a main discontinuous flow variable through the complete wave structure and cannot be recovered correctly by some numerical techniques when simulating the associated Riemann problem. Simulations are validated by comparing the results of the numerical calculation qualitatively with OpenFOAM software. Simulations also indicate that OpenFOAM is unable to resolve the relative velocity associated with the Riemann problem.

  20. Some issues in the simulation of two-phase flows: The relative velocity

    Energy Technology Data Exchange (ETDEWEB)

    Gräbel, J.; Hensel, S.; Ueberholz, P.; Farber, P. [Niederrhein University of Applied Sciences, Institute for Modelling and High Performance Computing, Reinarzstraße 49, 47805 Krefeld (Germany); Zeidan, D. [School of Basic Sciences and Humanities, German Jordanian University, Amman (Jordan)

    2016-06-08

    In this paper we compare numerical approximations for solving the Riemann problem for a hyperbolic two-phase flow model in two-dimensional space. The model is based on mixture parameters of state where the relative velocity between the two-phase systems is taken into account. This relative velocity appears as a main discontinuous flow variable through the complete wave structure and cannot be recovered correctly by some numerical techniques when simulating the associated Riemann problem. Simulations are validated by comparing the results of the numerical calculation qualitatively with OpenFOAM software. Simulations also indicate that OpenFOAM is unable to resolve the relative velocity associated with the Riemann problem.

  1. Suppression of the p53- or pRB-mediated G1 checkpoint is required for E2F-induced S-phase entry

    DEFF Research Database (Denmark)

    Lomazzi, Marina; Moroni, M Cristina; Jensen, Michael R

    2002-01-01

    Deregulation of the retinoblastoma protein (pRB) pathway is a hallmark of cancer. In the absence of other genetic alterations, this deregulation results in lack of differentiation, hyperproliferation and apoptosis. The pRB protein acts as a transcriptional repressor by targeting the E2F...... transcription factors, whose functions are required for entry into S phase. Increased E2F activity can induce S phase in quiescent cells--this is a central element of most models for the development of cancer. We show that although E2F1 alone is not sufficient to induce S phase in diploid mouse and human...

  2. Cyclin E-induced S phase without activation of the pRb/E2F pathway

    DEFF Research Database (Denmark)

    Lukas, J; Herzinger, T; Hansen, Klaus

    1997-01-01

    In cells of higher eukaryotes, cyclin D-dependent kinases Cdk4 and Cdk6 and, possibly, cyclin E-dependent Cdk2 positively regulate the G1- to S-phase transition, by phosphorylating the retinoblastoma protein (pRb), thereby releasing E2F transcription factors that control S-phase genes. Here we...

  3. Measurements of the $C\\!P$-violating phase $\\phi_{s}$ at LHCb

    CERN Document Server

    Batozskaya, Varvara

    2018-01-01

    The measurement of the mixing-induced $C\\!P$-violating phase $\\phi_{s}$ in the $B^{0}_{s}-\\bar{B}^{0}_{s}$ system is one of the key goals of the LHCb experiment. It has been measured at the LHCb collaboration exploiting the Run~I data set and using several decay channels. In particular, the most recent Run~I result has been obtained analyzing $B^{0}_{s}\\to J/\\psi K^{+}K^{-}$ candidates in the mass region above the $\\phi(1020)$ resonance. Despite the large improvements in the sensitivity of $\\phi_{s}$ during the last decade, the precision is still limited by the available statistics.

  4. Study of pressure drop, void fraction and relative permeabilities of two phase flow through porous media

    International Nuclear Information System (INIS)

    Chu, W.; Dhir, V.K.; Marshall, J.

    1983-01-01

    An experimental investigation of two phase flow through porous layers formed of non-heated glass particles (nominal diameter 1 to 6 mm) has been made. Particulate bed depths of 30 cm and 70 cm were used. The effect of particle size, particle size distribution and bed porosity on void fraction and pressure drop through a particulate bed formed in a cylindrical test section has been investigated. The superficial velocity of liquid (water) is varied from 1.83 to 18.3 mm/s while the superficial velocity of gas (air) is varied from 0 to 68.4 mm/s. These superficial velocities were chosen so that pressure drop and void fraction measurement could be made for the porous layer in fixed and fluidized states. A model based on drift flux approach has been developed for the void fraction. Using the two phase friction pressure drop data, the relative permeabilities of the two phases have been concluded with void fraction. The void fraction and two phase friction pressure gradient in beds composed of mixtures of spherical particles as well as sharps of different nominal sizes have also been examined. It is found that the models for single size particles are also applicable to mixtures of particles if a mean particle diameter for the mixture is defined

  5. Magnetic excitations in ferromagnetic phase of MnP

    International Nuclear Information System (INIS)

    Yano, Shin-ichiro; Itoh, Shinichi; Yokoo, Tetsuya; Satoh, Setsuo; Kawana, Daichi; Kousaka, Yusuke; Akimitsu, Jun; Endoh, Yasuo

    2013-01-01

    Inelastic neutron scattering experiments were performed on an intermetallic compound, MnP. We used a newly developed High Resolution Chopper Spectrometer, HRC, for energy transfers E≤75meV, besides various triple axis spectrometers; LTAS for energy transfers E≤2meV, TOPAN for E≤7.5meV and TAS-1 for E≤35meV. Spin wave excitations were observed in the ferromagnetic phase of MnP in the entire Brillouin zone along the a ⁎ - and b ⁎ -axes. The zone boundary energies of spin waves were determined to be around 60 meV along the a ⁎ -axis and around 75 meV along the b ⁎ -axis, and the dispersion relations showed two branches for both axes. The observed dispersion relations of spin waves were well described by an isotropic Heisenberg interaction adding a single ion anisotropy with two sub-lattices. - Highlights: • Inelastic neutron scattering experiments were performed mainly using pulsed neutrons. • Spin waves were observed in the ferromagnetic phase of an intermetallic compound MnP. • The dispersion relations were determined entirely along the a ⁎ - and b ⁎ -axes. • We could describe the observed dispersion relations by a two sub-lattice model

  6. The analysis of two-phase flow and heat transfer using a multidimensional, four field, two-fluid model

    International Nuclear Information System (INIS)

    Lahey, Richard T.; Drew, Donald A.

    2001-01-01

    This paper reviews the state-of-the-art in the prediction of multidimensional multiphase flow and heat transfer phenomena using a four field, two-fluid model. It is shown that accurate mechanistic computational fluid dynamic (CFD) predictions are possible for a wide variety of adiabatic and diabatic flows using this computational model. In particular, the model is able to predict the bubbly air/water upflow data of Serizawa (Serizawa, A., 1974. Fluid dynamic characteristics of two-phase flow. Ph.D. thesis, (Nuclear Engineering), Kyoto University, Japan), the downflow data of Wang et al. (Wang, S.K., Lee, S.J., Lahey Jr., R.T., Jones, O.C., 1987. 3-D turbulence structure and phase distribution measurements in bubbly two-phase flows. Int. J. Multiphase Flow 13 (3), 327-343), the isosceles triangle upflow data of Lopez de Bertodano et al. (Lopez de Bertodano, M., Lahey Jr., R.T., Jones, O.C., 1994b. Phase distribution in bubbly two-phase flow in vertical ducts. Int. J. Multiphase Flow 20 (5), 805-818), the heated annular R-113 subcooled boiling data of Velidandala, et al. (Velidandla, V., Pulta, S., Roy, P., Kaira, S.P., 1995. Velocity field in turbulent subcooled boiling flow. ASME Preprint HTD-314, 107-123) and the R-113 CHF data of Hino and Ueda (Hino, R., Ueda, T., 1985. Studies on heat transfer and flow characteristics in subcooled boiling-part 2, flow characteristics. Int. J. Multiphase Flow 11, 283-297). It can also predict external two-phase flows, such as those for spreading two-phase jets (Bonetto, F., Lahey Jr., R.T., 1993. An experimental study on air carryunder due to a plunging liquid jet. Int. J. Multiphase Flow 19 (2), 281-294) and multiphase flows around the hull of naval surface ships (Carrica, P.M., Bonetto, F., Drew, D.A., Lahey, R.T., 1999. A polydispersed model for bubbly two-phase flow around a surface ship. Int. J. Multiphase Flow 25 (2), 257-305)

  7. Uniqueness of Specific Interfacial Area–Capillary Pressure–Saturation Relationship Under Non-Equilibrium Conditions in Two-Phase Porous Media Flow

    KAUST Repository

    Joekar-Niasar, Vahid; Hassanizadeh, S. Majid

    2012-01-01

    The capillary pressure-saturation (P c-S w) relationship is one of the central constitutive relationships used in two-phase flow simulations. There are two major concerns regarding this relation. These concerns are partially studied in a

  8. Effect of different pH-values on process parameters in two-phase anaerobic digestion of high-solid substrates.

    Science.gov (United States)

    Lindner, Jonas; Zielonka, Simon; Oechsner, Hans; Lemmer, Andreas

    2015-01-01

    In many publications, primary fermentation is described as a limiting step in the anaerobic digestion of fibre-rich biomass [Eastman JA, Ferguson JF. Solubilization of particulacte carbon during the anaerobic digeston. J WPCF. 1981;53:352-366; Noike T, Endo G, Chang J, Yaguchi J, Matsumoto J. Characteristics of carbohydrate degradation and the rate-limiting step in anaerobic digestion. Biotechnol Bioeng. 1985;27:1482-1489; Arntz HJ, Stoppok E, Buchholz K. Anaerobic hydroysis of beet pulp-discontiniuous experiments. Biotechnol Lett. 1985;7:113-118]. The microorganisms of the primary fermentation process differ widely from the methanogenic microorganisms [Pohland FG, Ghosh S. Developments in anaerobic stabilization of organic wastes-the two-phase concept. Environ Lett. 1971;1:255-266]. To optimize the biogas process, a separation in two phases is suggested by many authors [Fox P, Pohland GK. Anaerobic treatment applications and fundamentals: substrate specificity during phase separation. Water Environ Res. 1994;66:716-724; Cohen A, Zoetemeyer RJ, van Deursen A, van Andel JG. Anaerobic digestion of glucose with separated acid production and methane formation. Water Res. 1979;13:571-580]. To carry out the examination, a two-phase laboratory-scale biogas plant was established, with a physical phase separation. In previous studies, the regulation of the pH-value during the acid formation was usually carried out by the addition of sodium hydroxide [Cohen A, Zoetemeyer RJ, van Deursen A, van Andel JG. Anaerobic digestion of glucose with separated acid production and methane formation. Water Res. 1979;13:571-580; Ueno Y, Tatara M, Fukui H, Makiuchi T, Goto M, Sode K. Production of hydrogen and methane from organic solid wastes by phase separation of anaerobic process. Bioresour Technol. 2007;98:1861-1865; Zoetemeyer RJ, van den Heuvel JC, Cohen A. pH influence on acidogenic dissimilation of glucose in an anaerobic digestor. Water Res. 1982;16:303-311]. A new technology

  9. Experimental study and thermodynamic modeling of the phase relation in the Fe-S-Si system with implications for the distribution of S and Si in a partially solidified core

    Science.gov (United States)

    Tao, R.; Fei, Y.

    2017-12-01

    Planetary cooling leads to solidification of any initially molten metallic core. Some terrestrial cores (e.g. Mercury) are formed and differentiated under relatively reduced conditions, and they are thought to be composed of Fe-S-Si. However, there are limited understanding of the phase relations in the Fe-S-Si system at high pressure and temperature. In this study, we conducted high-pressure experiments to investigate the phase relations in the Fe-S-Si system up to 25 GPa. Experimental results show that the liquidus and solidus in this study are slightly lower than those in the Fe-S binary system for the same S concentration in liquid at same pressure. The Fe3S, which is supposed to be the stable sub-solidus S-bearing phase in the Fe-S binary system above 17 GPa, is not observed in the Fe-S-Si system at 21 GPa. Almost all S prefers to partition into liquid, while the distribution of Si between solid and liquid depends on experimental P and T conditions. We obtained the partition coefficient log(KDSi) by fitting the experimental data as a function of P, T and S concentration in liquid. At a constant pressure, the log(KDSi) linearly decreases with 1/T(K). With increase of pressure, the slopes of linear correlation between log(KDSi) and 1/T(K) decreases, indicating that more Si partitions into solid at higher pressure. In order to interpolate and extrapolate the phase relations over a wide pressure and temperature range, we established a comprehensive thermodynamic model in the Fe-S-Si system. The results will be used to constrain the distribution of S and Si between solid inner core and liquid outer core for a range of planet sizes. A Si-rich solid inner core and a S-rich liquid outer core are suggested for an iron-rich core.

  10. Pressure Drop Correlations of Single-Phase and Two-Phase Flow in Rolling Tubes

    International Nuclear Information System (INIS)

    Xia-xin Cao; Chang-qi Yan; Pu-zhen Gao; Zhong-ning Sun

    2006-01-01

    A series of experimental studies of frictional pressure drop for single phase and two-phase bubble flow in smooth rolling tubes were carried out. The tube inside diameters were 15 mm, 25 mm and 34.5 mm respectively, the rolling angles of tubes could be set as 10 deg. and 20 deg., and the rolling periods could be set as 5 s, 10 s and 15 s. Combining with the analysis of single-phase water motion, it was found that the traditional correlations for calculating single-phase frictional coefficient were not suitable for the rolling condition. Based on the experimental data, a new correlation for calculating single-phase frictional coefficient under rolling condition was presented, and the calculations not only agreed well with the experimental data, but also could display the periodically dynamic characteristics of frictional coefficients. Applying the new correlation to homogeneous flow model, two-phase frictional pressure drop of bubble flow in rolling tubes could be calculated, the results showed that the relative error between calculation and experimental data was less than ± 25%. (authors)

  11. Models for assessing the relative phase velocity in a two-phase flow. Status report

    International Nuclear Information System (INIS)

    Schaffrath, A.; Ringel, H.

    2000-06-01

    The knowledge of slip or drift flux in two phase flow is necessary for several technical processes (e.g. two phase pressure losses, heat and mass transfer in steam generators and condensers, dwell period in chemical reactors, moderation effectiveness of two phase coolant in BWR). In the following the most important models for two phase flow with different phase velocities (e.g. slip or drift models, analogy between pressure loss and steam quality, ε - ε models and models for the calculation of void distribution in reposing fluids) are classified, described and worked up for a further comparison with own experimental data. (orig.)

  12. Nature of low dimensional structural modulations and relative phase stability in RexMo(W)1-xS2 transition metal dichalcogenide alloys

    KAUST Repository

    Sahu, R.; Bhat, U.; Batra, Nitin M; Sharona, H.; Vishal, B.; Sarkar, S.; Devi, Assa Aravindh Sasikala; Peter, S. C.; Roqan, Iman S.; Costa , P. M. F. J.; Datta, Ranjan

    2017-01-01

    We report on the various types of Peierls like two dimensional structural modulations and relative phase stability of 2H and 1T poly-types in the RexMo1-xS2 and RexW1-xS2 alloy system. Theoretical calculation predicts a polytype phase transition

  13. Anisotropic thermal properties and ferroelectric phase transitions in layered CuInP2S6 and CuInP2Se6 crystals

    Science.gov (United States)

    Liubachko, V.; Shvalya, V.; Oleaga, A.; Salazar, A.; Kohutych, A.; Pogodin, A.; Vysochanskii, Yu. M.

    2017-12-01

    Thermal diffusivity and thermal conductivity have been studied for the layered crystals CuInP2S6, CuInP2Se6 from 30 K to 350 K, showing a relevant thermal anisotropy. Heat is much more efficiently transferred within the layers than perpendicular to them. The ferrielectric transition in CuInP2S6 is proven to be clearly first order while the ferroelectric one in CuInP2Se6 has a weak first order character. The behavior of the thermal conductivity as a function of temperature in the ferroelectric phases shows that heat conduction is phonon driven. Disorder in the paraelectric phases due to hopping motions of Cu ions significantly reduces the thermal conductivity to extremely low values.

  14. Modeling of Multiphase with Respect to Low Interfacial Tension by Pseudo-Two-Phase Relative Permeability Functions Modélisation d'un écoulement polyphasique à faible tension interfaciale par des fonctions pseudo-biphasiques de perméabilité relative

    Directory of Open Access Journals (Sweden)

    Pusch G.

    2006-11-01

    Full Text Available A new 2-parameter desaturation function is introduced which offers a broader range of applicability to reservoir rock. Based on this function two-phase relative permeabilities are derived for oil phase and microemulsion flow. These functions are used to match a laboratory experiment by using surfactant flooding for a single surfactant system. Les auteurs présentent une nouvelle fonction de désaturation à deux paramètres qui offre une plus large gamme de possibilités d'application aux roches réservoir. On tire de cette fonction des perméabilités relatives biphasiques pour l'écoulement de la phase pétrole et d'une microémulsion. Ces fonctions sont utilisées pour reproduire une expérience de laboratoire avec injection de surfactant pour un seul système surfactant.

  15. Uniqueness of specific interfacial area-capillary pressure-saturation relationship under non-equilibrium conditions in two-phase porous media flow

    NARCIS (Netherlands)

    Joekar-Niasar, V.; Hassanizadeh, S.M.

    2012-01-01

    The capillary pressure–saturation (P c–S w) relationship is one of the central constitutive relationships used in two-phase flow simulations. There are two major concerns regarding this relation. These concerns are partially studied in a hypothetical porous medium using a dynamic pore-network model

  16. [Phase transfer catalyzed bioconversion of penicillin G to 6-APA by immobilized penicillin acylase in recyclable aqueous two-phase systems with light/pH sensitive copolymers].

    Science.gov (United States)

    Jin, Ke-ming; Cao, Xue-jun; Su, Jin; Ma, Li; Zhuang, Ying-ping; Chu, Ju; Zhang, Si-liang

    2008-03-01

    Immobilized penicillin acylase was used for bioconversion of penicillin PG into 6-APA in aqueous two-phase systems consisting of a light-sensitive polymer PNBC and a pH-sensitive polymer PADB. Partition coefficients of 6-APA was found to be about 5.78 in the presence of 1% NaCl. Enzyme kinetics showed that the reaction reached equilibrium at roughly 7 h. The 6-APA mole yields were 85.3% (pH 7.8, 20 degrees C), with about 20% increment as compared with the reaction of single aqueous phase buffer. The partition coefficient of PG (Na) varied scarcely, while that of the product, 6-APA and phenylacetic acid (PA) significantly varied due to Donnan effect of the phase systems and hydrophobicity of the products. The variation of the partition coefficients of the products also affected the bioconversion yield of the products. In the aqueous two-phase systems, the substrate, PG, the products of 6-APA and PA were biased in the top phase, while immobilized penicillin acylase at completely partitioned at the bottom. The substrate and PG entered the bottom phase, where it was catalyzed into 6-APA and PA and entered the top phase. Inhibition of the substrate and products was removed to result in improvement of the product yield, and the immobilized enzyme showed higher efficiency than the immobilized cells and occupied smaller volume. Compared with the free enzyme, immobilized enzyme had greater stability, longer life-time, and was completely partitioned in the bottom phase and recycle. Bioconversion in two-phase systems using immobilized penicillin acylase showed outstanding advantage. The light-sensitive copolymer forming aqueous two-phase systems could be recovered by laser radiation at 488 nm or filtered 450 nm light, while pH-sensitive polymer PADB could be recovered at the isoelectric point (pH 4.1). The recovery of the two copolymers was between 95% and 99%.

  17. A Switchable Molecular Dielectric with Two Sequential Reversible Phase Transitions: [(CH3)4P]4[Mn(SCN)6].

    Science.gov (United States)

    Li, Qiang; Shi, Ping-Ping; Ye, Qiong; Wang, Hui-Ting; Wu, De-Hong; Ye, Heng-Yun; Fu, Da-Wei; Zhang, Yi

    2015-11-16

    A new organic-inorganic hybrid switchable and tunable dielectric compound, [(CH3)4P]4[Mn(SCN)6] (1), exhibits three distinct dielectric states above room temperature and undergoes two reversible solid-state phase transitions, including a structural phase transition at 330 K and a ferroelastic phase transition with the Aizu notation of mmmF2/m at 352 K. The variable-temperature structural analyses disclose that the origin of the phase transitions and dielectric anomalies can be ascribed to the reorientation or motion of both the [(CH3)4P](+) cations and [Mn(SCN)6](4-) anions in solid-state crystals.

  18. $\\mathcal{CP}$ violating phase $\\phi_s$ and penguin pollution in $B_s^0\\to J/\\psi K^+K^-$ with LHCb

    CERN Multimedia

    Vazquez Sierra, Carlos

    2015-01-01

    CP violating phase φs appears in b → anti(c)cs transitions due to the interference between the direct decay and the decay after the Bs⁰-anti(Bs⁰) mixing. In SM, φs = -2βs + δP, where -2βs is related to CKM matrix elements and δP is the penguin phase where contributions due to penguin diagrams are taken into account, being this δP phase also the main source of theoretical uncertainty in φs. This φs phase is very sensitive to possible NP (new particles contributing to box diagrams during the mixing, several possible BSM scenarios are presented), so δP should be estimated in order to disentangle these penguin pollution contributions from possible NP contributions, φs(LHCb) = -2βs + δP + δNP. The decay Bs⁰ → J/ψ K⁺K⁻ is a golden decay for φs measurement: latest LHCb combined result also including Bs⁰ → J/ψ π⁺π⁻ measurements is φs = -0.010 ± 0.039 rad, which is in excellent agreement with SM. The penguin pollution phase δP can be estimated using B⁰ → J/ψ ρ⁰ and B...

  19. Preparation of CdS microtrumpets from a solvent extraction system by a two-phase approach

    International Nuclear Information System (INIS)

    Geng, Aifang; Liu, Yubing; Liao, Wuping

    2011-01-01

    Highlights: → CdS microtrumpets were prepared from an extraction system by a two-phase approach. → Triethanolamine plays a crucial role in the formation of the trumpets. → Some micro-lotus seedpods can also be obtained with trihydroxymethyl aminomethane. -- Abstract: CdS microtrumpets with the length being of about 4 μm and the bell wall being of 100 nm have been prepared using a cadmium di-(2-ethylhexyl) phosphoric acid chelate as the precursor by a two-phase thermal approach. The products were characterized by powder X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM) and UV-vis spectroscopy. The effects of temperature, reaction time, and co-surfactant on the morphology were also examined. It was found that the co-surfactant triethanolamine plays a crucial role in the formation of the cubic phase trumpet-like CdS microstructures.

  20. Measurement of average density and relative volumes in a dispersed two-phase fluid

    Science.gov (United States)

    Sreepada, Sastry R.; Rippel, Robert R.

    1992-01-01

    An apparatus and a method are disclosed for measuring the average density and relative volumes in an essentially transparent, dispersed two-phase fluid. A laser beam with a diameter no greater than 1% of the diameter of the bubbles, droplets, or particles of the dispersed phase is directed onto a diffraction grating. A single-order component of the diffracted beam is directed through the two-phase fluid and its refraction is measured. Preferably, the refracted beam exiting the fluid is incident upon a optical filter with linearly varing optical density and the intensity of the filtered beam is measured. The invention can be combined with other laser-based measurement systems, e.g., laser doppler anemometry.

  1. S2p core level spectroscopy of short chain oligothiophenes

    Science.gov (United States)

    Baseggio, O.; Toffoli, D.; Stener, M.; Fronzoni, G.; de Simone, M.; Grazioli, C.; Coreno, M.; Guarnaccio, A.; Santagata, A.; D'Auria, M.

    2017-12-01

    The Near-Edge X-ray-Absorption Fine-Structure (NEXAFS) and X-ray Photoemission Spectroscopy (XPS) of short-chain oligothiophenes (thiophene, 2,2'-bithiophene, and 2,2':5',2″-terthiophene) in the gas phase have been measured in the sulfur L2,3-edge region. The assignment of the spectral features is based on the relativistic two-component zeroth-order regular approximation time dependent density functional theory approach. The calculations allow us to estimate both the contribution of the spin-orbit splitting and of the molecular-field splitting to the sulfur binding energies and give results in good agreement with the experimental measurements. The deconvolution of the calculated S2p NEXAFS spectra into the two manifolds of excited states converging to the LIII and LII edges facilitates the attribution of the spectral structures. The main S2p NEXAFS features are preserved along the series both as concerns the energy positions and the nature of the transitions. This behaviour suggests that the electronic and geometrical environment of the sulfur atom in the three oligomers is relatively unaffected by the increasing chain length. This trend is also observed in the XPS spectra. The relatively simple structure of S2p NEXAFS spectra along the series reflects the localized nature of the virtual states involved in the core excitation process.

  2. Hydrodynamics of single- and two-phase flow in inclined rod arrays

    International Nuclear Information System (INIS)

    Ebeling-Koning, D.B.; Todreas, N.E.

    1983-09-01

    Required inputs for thermal-hydraulic codes are constitutive relations for fluid-solid flow resistance, in single-phase flow, and interfacial momentum exchange (relative phase motion), in two-phase flow. An inclined rod array air-water experiment was constructed to study the hydrodynamics of multidimensional porous medium flow in rod arrays. Velocities, pressures, and bubble distributions were measured in square rod arrays of P/d = 1.5, at 0, 30, 45, and 90 degree inclinations to the vertical flow direction. Constitutive models for single-phase flow resistance are reviewed, new comprehensive models developed, and an assessment with previously published and new data made. The principle of superimposing one-dimensional correlations proves successful for turbulent single-phase inclined flow. For bubbly two-phase incline flow a new flow separation phenomena was observed and modeled. A two-region liquid velocity model is developed to explain the experimentally observed phenomena. Fundamental data for bubbles rising in rod arrays were also taken

  3. A study of the Ne 2s2p{sup 5}({sup 3}P)3s and 3p correlation satellites up to 75 eV above threshold

    Energy Technology Data Exchange (ETDEWEB)

    Yarzhemsky, V G [RAS Kurnakov Institute of General and Inorganic Chemistry, Moscow (Russian Federation); Amusia, M Ya [Racah Institute of Physics, The Hebrew University, Jerusalem 91904 (Israel); Bolognesi, P; Avaldi, L, E-mail: lorenzo.avaldi@imip.cnr.i [CNR-Istituto di Metodologie Inorganiche e dei Plasmi, Area della Ricerca di Roma 1, CP 10, 00016 Monterotondo Scalo (Italy)

    2010-09-28

    The 2s2p{sup 5}({sup 3}P)3s {sup 2}P, 3p {sup 2}D and {sup 2}S satellite states of neon have been studied at several energies from 5 to 75 eV above their respective thresholds. The relative intensities of the satellite states with respect to their main lines shed light on the nature of the many-electron correlations leading to the formation of these satellites. The experimental results are compared with a calculation which makes use of a random phase approximation with exchange (RPAE) cross sections, and takes into account the shake-up and direct knock-out channels as well as their interference.

  4. Crystallization and Characterization of Galdieria sulphuraria RUBISCO in Two Crystal Forms: Structural Phase Transition Observed in P21 Crystal Form

    Directory of Open Access Journals (Sweden)

    Boguslaw Stec

    2007-10-01

    Full Text Available We have isolated ribulose-1,5-bisphosphate-carboxylase/oxygenase (RUBISCOfrom the red algae Galdieria Sulphuraria. The protein crystallized in two different crystalforms, the I422 crystal form being obtained from high salt and the P21 crystal form beingobtained from lower concentration of salt and PEG. We report here the crystallization,preliminary stages of structure determination and the detection of the structural phasetransition in the P21 crystal form of G. sulphuraria RUBISCO. This red algae enzymebelongs to the hexadecameric class (L8S8 with an approximate molecular weight 0.6MDa.The phase transition in G. sulphuraria RUBISCO leads from two hexadecamers to a singlehexadecamer per asymmetric unit. The preservation of diffraction power in a phasetransition for such a large macromolecule is rare.

  5. P-S & S-P Elastic Wave Conversions from Linear Arrays of Oriented Microcracks

    Science.gov (United States)

    Jiang, L.; Modiriasari, A.; Bobet, A.; Pyrak-Nolte, L. J.

    2017-12-01

    Natural and induced processes can produce oriented mechanical discontinuities such as en echelon cracks, fractures and faults. Previous research has shown that compressional to shear (P-S) wave conversions occur at normal incidence to a fracture because of cross-coupling fracture compliances (Nakagawa et al., 2000). Here, experiments and computer simulation are presented to demonstrate the link among cross-coupling stiffness, microcrack orientation and energy partitioning among P, S, and P-S/S-P waves. A FormLabs 2 3D printer was used to fabricate 7 samples (50 mm x 50 mm x 100 mm) with linear arrays of microcracks oriented at 0, 15, 30, 45, 60, 75, and 900 with a print resolution of 0.025 mm. The microcracks were elliptical in cross-sections (2 mm long by 1 mm wide), through the 50 mm thickness of sample, and spaced 3 mm (center-to-center for adjacent cracks). A 25 mm length of each sample contained no microcracks to act as a reference material. Broadband transducers (0.2-1.5 MHz) were used to transmit and receive P and polarized S wave signals that were propagated at normal incidence to the linear array of microcracks. P-wave amplitude increased, while S-wave amplitude remained relatively constant, as the microcrack orientation increased from 0o to 90o. At normal incidence, P-S and S-P wave conversions emerged and increased in amplitude as the crack inclination increased from 00 to 450. From 450 to 900, the amplitude of these converted modes decreased. Between negative and positive crack angles, the P-to-S and S-to-P waves were 1800 phase reversed. The observed energy partitioning matched the computed compliances obtained from numerical simulations with ABAQUS. The cross-coupling compliance for cracks inclined at 450 was found to be the smallest magnitude. 3D printing enabled the study of microstructural effects on macro-scale wave measurements. Information on the orientation of microcracks or even en echelon fractures and faults is contained in P-S conversions

  6. Whisker Deprivation Drives Two Phases of Inhibitory Synapse Weakening in Layer 4 of Rat Somatosensory Cortex.

    Directory of Open Access Journals (Sweden)

    Melanie A Gainey

    Full Text Available Inhibitory synapse development in sensory neocortex is experience-dependent, with sustained sensory deprivation yielding fewer and weaker inhibitory synapses. Whether this represents arrest of synapse maturation, or a more complex set of processes, is unclear. To test this, we measured the dynamics of inhibitory synapse development in layer 4 of rat somatosensory cortex (S1 during continuous whisker deprivation from postnatal day 7, and in age-matched controls. In deprived columns, spontaneous miniature inhibitory postsynaptic currents (mIPSCs and evoked IPSCs developed normally until P15, when IPSC amplitude transiently decreased, recovering by P16 despite ongoing deprivation. IPSCs remained normal until P22, when a second, sustained phase of weakening began. Delaying deprivation onset by 5 days prevented the P15 weakening. Both early and late phase weakening involved measurable reduction in IPSC amplitude relative to prior time points. Thus, deprivation appears to drive two distinct phases of active IPSC weakening, rather than simple arrest of synapse maturation.

  7. Phase transitions in two dimensions

    International Nuclear Information System (INIS)

    Henderson, D.

    1980-01-01

    Although a two-dimensional solid with long-range translational order cannot existin the thermodynamic limit (N → ∞, V →∞, N/V finite) macroscopic samples of two-dimensional solids can exist. In this work, stability of the phase was determined by the usuar method of equating the pressure and chemical potential of the phases. (A.C.A.S.) [pt

  8. Importance of sequential two-step transfer process in a ΔS = 1 and ΔT = 1 inelastic transition of 14N(p, p')14N reaction

    International Nuclear Information System (INIS)

    Aoki, Y.; Kunori, S.; Nagano, K.; Toba, Y.; Yagi, K.

    1981-01-01

    Differential cross sections and vector analyzing powers for 14 N(p, p') and 14 N(p, d) reactions have been measured at E sub(p) = 21.0 MeV to elucidate the reaction mechanism and the effective interaction for the ΔS = ΔT = 1 transition in 14 N(p, p') 14 N(2.31 MeV) reaction. The data are analyzed in terms of finite-range distorted wave Borm approximation (DWBA) which include direct, knock-on exchange and (p, d)(d, p') two-step processes. Shell model wave functions of Cohen and Kurath are used. The data for the first excited state is reasonably well explained by introducing two-step process. The two-step process explains half of the experimental intensity. Moreover vector analyzing power can hardly be explained without introducing this two-step process. Vector analyzing power of protons leading to the second excited state in 14 N is better explained by introducing macroscopic calculation. The data for 14 N(p, d) 13 N(gs) reaction are well explained by a suitable choice of deuteron optical potential. Knock-on exchange contribution is relatively small. Importance of this two-step process for ΔS = ΔT = 1 transition is discussed up to 40 MeV. (author)

  9. P-phase precipitation and its effect on martensitic transformation in (Ni,Pt)Ti shape memory alloys

    International Nuclear Information System (INIS)

    Gao, Y.; Zhou, N.; Yang, F.; Cui, Y.; Kovarik, L.; Hatcher, N.; Noebe, R.; Mills, M.J.; Wang, Y.

    2012-01-01

    A new precipitate phase named P-phase has recently been identified in (Ni,Pt)Ti high temperature shape memory alloys. In order to understand the roles played by the fine coherent P-phase precipitates in determining the martensitic transformation temperature (M s ), strength of the B2 matrix phase, dimensional stability and shape memory effect of the alloys, a phase field model of P-phase precipitation is developed. Model inputs, including lattice parameters, precipitate–matrix orientation relationship, elastic constants and free energy data, are obtained from experimental characterization, ab initio calculations and thermodynamic databases. Through computer simulations, the shape and spatial distribution of the P-phase precipitates, as well as the compositional and stress fields around them, are quantitatively determined. On this basis, the elastic interaction energy between the P-phase precipitates and a martenstic nucleus is calculated. It is found that both the chemical non-uniformity and stress field associated with the P-phase precipitates are in favor of the martensitic transformation. Their relative contributions to the increase in M s temperature are quantified as a function of aging time and the result seems to agree with the experimental measurements. The shape and spatial distribution of the P-phase precipitates predicted by the simulations also agree well with experimental observations.

  10. Stratified steady and unsteady two-phase flows between two parallel plates

    International Nuclear Information System (INIS)

    Sim, Woo Gun

    2006-01-01

    To understand fluid dynamic forces acting on a structure subjected to two-phase flow, it is essential to get detailed information about the characteristics of two-phase flow. Stratified steady and unsteady two-phase flows between two parallel plates have been studied to investigate the general characteristics of the flow related to flow-induced vibration. Based on the spectral collocation method, a numerical approach has been developed for the unsteady two-phase flow. The method is validated by comparing numerical result to analytical one given for a simple harmonic two-phase flow. The flow parameters for the steady two-phase flow, such as void fraction and two-phase frictional multiplier, are evaluated. The dynamic characteristics of the unsteady two-phase flow, including the void fraction effect on the complex unsteady pressure, are illustrated

  11. Phase II and III Clinical Studies of Diphtheria-Tetanus-Acellular Pertussis Vaccine Containing Inactivated Polio Vaccine Derived from Sabin Strains (DTaP-sIPV).

    Science.gov (United States)

    Okada, Kenji; Miyazaki, Chiaki; Kino, Yoichiro; Ozaki, Takao; Hirose, Mizuo; Ueda, Kohji

    2013-07-15

    Phase II and III clinical studies were conducted to evaluate immunogenicity and safety of a novel DTaP-IPV vaccine consisting of Sabin inactivated poliovirus vaccine (sIPV) and diphtheria-tetanus-acellular pertussis vaccine (DTaP). A Phase II study was conducted in 104 healthy infants using Formulation H of the DTaP-sIPV vaccine containing high-dose sIPV (3, 100, and 100 D-antigen units for types 1, 2, and 3, respectively), and Formulations M and L, containing half and one-fourth of the sIPV in Formulation H, respectively. Each formulation was administered 3 times for primary immunization and once for booster immunization. A Phase III study was conducted in 342 healthy infants who received either Formulation M + oral polio vaccine (OPV) placebo or DTaP + OPV. The OPV or OPV placebo was orally administered twice between primary and booster immunizations. Formulation M was selected as the optimum dose. In the Phase III study, the seropositive rate was 100% for all Sabin strains after primary immunization, and the neutralizing antibody titer after booster immunization was higher than in the control group (DTaP + OPV). All adverse reactions were clinically acceptable. DTaP-sIPV was shown to be a safe and immunogenic vaccine. JapicCTI-121902 for Phase II study, JapicCTI-101075 for Phase III study (http://www.clinicaltrials.jp/user/cte_main.jsp).

  12. Modeling two-phase flow in PEM fuel cell channels

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Yun; Basu, Suman; Wang, Chao-Yang [Electrochemical Engine Center (ECEC), and Department of Mechanical and Nuclear Engineering, The Pennsylvania State University, University Park, PA 16802 (United States)

    2008-05-01

    This paper is concerned with the simultaneous flow of liquid water and gaseous reactants in mini-channels of a proton exchange membrane (PEM) fuel cell. Envisaging the mini-channels as structured and ordered porous media, we develop a continuum model of two-phase channel flow based on two-phase Darcy's law and the M{sup 2} formalism, which allow estimate of the parameters key to fuel cell operation such as overall pressure drop and liquid saturation profiles along the axial flow direction. Analytical solutions of liquid water saturation and species concentrations along the channel are derived to explore the dependences of these physical variables vital to cell performance on operating parameters such as flow stoichiometric ratio and relative humility. The two-phase channel model is further implemented for three-dimensional numerical simulations of two-phase, multi-component transport in a single fuel-cell channel. Three issues critical to optimizing channel design and mitigating channel flooding in PEM fuel cells are fully discussed: liquid water buildup towards the fuel cell outlet, saturation spike in the vicinity of flow cross-sectional heterogeneity, and two-phase pressure drop. Both the two-phase model and analytical solutions presented in this paper may be applicable to more general two-phase flow phenomena through mini- and micro-channels. (author)

  13. Syntrophic acetate oxidation in two-phase (acid-methane) anaerobic digesters.

    Science.gov (United States)

    Shimada, T; Morgenroth, E; Tandukar, M; Pavlostathis, S G; Smith, A; Raskin, L; Kilian, R E

    2011-01-01

    The microbial processes involved in two-phase anaerobic digestion were investigated by operating a laboratory-scale acid-phase (AP) reactor and analyzing two full-scale, two-phase anaerobic digesters operated under mesophilic (35 °C) conditions. The digesters received a blend of primary sludge and waste activated sludge (WAS). Methane levels of 20% in the laboratory-scale reactor indicated the presence of methanogenic activity in the AP. A phylogenetic analysis of an archaeal 16S rRNA gene clone library of one of the full-scale AP digesters showed that 82% and 5% of the clones were affiliated with the orders Methanobacteriales and Methanosarcinales, respectively. These results indicate that substantial levels of aceticlastic methanogens (order Methanosarcinales) were not maintained at the low solids retention times and acidic conditions (pH 5.2-5.5) of the AP, and that methanogenesis was carried out by hydrogen-utilizing methanogens of the order Methanobacteriales. Approximately 43, 31, and 9% of the archaeal clones from the methanogenic phase (MP) digester were affiliated with the orders Methanosarcinales, Methanomicrobiales, and Methanobacteriales, respectively. A phylogenetic analysis of a bacterial 16S rRNA gene clone library suggested the presence of acetate-oxidizing bacteria (close relatives of Thermacetogenium phaeum, 'Syntrophaceticus schinkii,' and Clostridium ultunense). The high abundance of hydrogen consuming methanogens and the presence of known acetate-oxidizing bacteria suggest that acetate utilization by acetate oxidizing bacteria in syntrophic interaction with hydrogen-utilizing methanogens was an important pathway in the second-stage of the two-phase digestion, which was operated at high ammonium-N concentrations (1.0 and 1.4 g/L). A modified version of the IWA Anaerobic Digestion Model No. 1 (ADM1) with extensions for syntrophic acetate oxidation and weak-acid inhibition adequately described the dynamic profiles of volatile acid production

  14. Two-phase flows and heat transfer within systems with ambient pressure above the thermodynamic critical pressure

    Science.gov (United States)

    Hendricks, R. C.; Braun, M. J.; Mullen, R. L.

    1986-01-01

    In systems where the design inlet and outlet pressure P sub amb are maintained above the thermodynamic critical pressure P sub c, it is often assumed that heat and mass transfer are governed by single-phase relations and that two-phase flows cannot occur. This simple rule of thumb is adequate in many low-power designs but is inadequate for high-performance turbomachines, boilers, and other systems where two-phase regions can exist even though P sub amb P sub c. Heat and mass transfer and rotordynamic-fluid-mechanic restoring forces depend on momentum differences, and those for a two-phase zone can differ significantly from those for a single-phase zone. By using a laminar, variable-property bearing code and a rotating boiler code, pressure and temperature surfaces were determined that illustrate nesting of a two-phase region within a supercritical pressure region. The method of corresponding states is applied to bearings with reasonable rapport.

  15. Phase and ellipticity dependence of the photoelectron angular distribution in non-resonant two-photon ionization of atomic hydrogen. I

    International Nuclear Information System (INIS)

    Faye, M; Wane, S T

    2011-01-01

    We study the ellipticity and the dependence on the phase lag (lead) (between the semimajor and the semiminor axes of the field components) of the photoelectron angular distribution (PAD) in the non-resonant two-photon ionization of atomic hydrogen. We establish exact analytical expressions for azimuthal PAD for 3s, 3p and 3d excited initial states, marked by the occurrence of an asymmetric term. This term gives rise to elliptic dichroism (ED), which can be obtained in two ways: either with the left (versus right) ellipticity, or with the phase lag (versus lead); for 3s and 3p initial states, it is shown that the quantum phase of continua is directly related to the phase lag, one-photon below-threshold ionization, and indirectly one photon above. Another important result is that the magnetic sublevels, m = 0, for 3p and m = ±1, for 3d, do not contribute to the azimuthal PAD. Our numerical results show, for 3s and 3d, and near-threshold ionization, that the PAD has maxima either along the semimajor or the semiminor axis, while for above-threshold ionization, they are always shifted from these axes. However, the maxima of the corresponding ED coincide with the PAD maxima, while for 3p, they are shifted from the PAD minima. A strong dependence of the ED sign is noted, regardless of the state or the process. However, strong ED signals are obtained for the 3s initial state and below-threshold ionization.

  16. Phase and ellipticity dependence of the photoelectron angular distribution in non-resonant two-photon ionization of atomic hydrogen. I

    Energy Technology Data Exchange (ETDEWEB)

    Faye, M; Wane, S T, E-mail: mamadou.faye@ucad.edu.sn [Departement de Physique, Faculte des Sciences et Techniques, Universite Cheikh Anta Diop, Boulevard Martin Luther King, (Corniche Ouest) BP 5005-Dakar Fann (Senegal)

    2011-03-14

    We study the ellipticity and the dependence on the phase lag (lead) (between the semimajor and the semiminor axes of the field components) of the photoelectron angular distribution (PAD) in the non-resonant two-photon ionization of atomic hydrogen. We establish exact analytical expressions for azimuthal PAD for 3s, 3p and 3d excited initial states, marked by the occurrence of an asymmetric term. This term gives rise to elliptic dichroism (ED), which can be obtained in two ways: either with the left (versus right) ellipticity, or with the phase lag (versus lead); for 3s and 3p initial states, it is shown that the quantum phase of continua is directly related to the phase lag, one-photon below-threshold ionization, and indirectly one photon above. Another important result is that the magnetic sublevels, m = 0, for 3p and m = {+-}1, for 3d, do not contribute to the azimuthal PAD. Our numerical results show, for 3s and 3d, and near-threshold ionization, that the PAD has maxima either along the semimajor or the semiminor axis, while for above-threshold ionization, they are always shifted from these axes. However, the maxima of the corresponding ED coincide with the PAD maxima, while for 3p, they are shifted from the PAD minima. A strong dependence of the ED sign is noted, regardless of the state or the process. However, strong ED signals are obtained for the 3s initial state and below-threshold ionization.

  17. Combined plasma gas-phase synthesis and colloidal processing of InP/ZnS core/shell nanocrystals

    Science.gov (United States)

    Gresback, Ryan; Hue, Ryan; Gladfelter, Wayne L.; Kortshagen, Uwe R.

    2011-12-01

    Indium phosphide nanocrystals (InP NCs) with diameters ranging from 2 to 5 nm were synthesized with a scalable, flow-through, nonthermal plasma process at a rate ranging from 10 to 40 mg/h. The NC size is controlled through the plasma operating parameters, with the residence time of the gas in the plasma region strongly influencing the NC size. The NC size distribution is narrow with the standard deviation being less than 20% of the mean NC size. Zinc sulfide (ZnS) shells were grown around the plasma-synthesized InP NCs in a liquid phase reaction. Photoluminescence with quantum yields as high as 15% were observed for the InP/ZnS core-shell NCs.

  18. S, P, D, F, G-waves KN phase shifts in a constituent quark model with a spin-orbit interaction

    International Nuclear Information System (INIS)

    Lemaire, S.; Labarsouque, J.; Silvestre-Brac, B.

    2002-01-01

    The I=1 and I=0 kaon-nucleon s, p, d, f, g-waves phase shifts have been calculated in a nonrelativistic quark potential model using the resonating group method (RGM). The interquark potential includes gluon exchanges with a spin-orbit interaction. This force has been determined to reproduce as well as possible the meson and baryon spectra. The same force is employed for the cluster and intercluster dynamics and the relative KN wave-function is calculated without any approximation. While some channels are correctly described, the theory is still unable to explain others

  19. Thermo-fluid dynamics of two-phase flow

    CERN Document Server

    Ishii, Mamoru; Ishii, Mamoru; Ishii, M

    2006-01-01

    Provides a very systematic treatment of two phase flow problems from a theoretical perspectiveProvides an easy to follow treatment of modeling and code devlopemnt of two phase flow related phenomenaCovers new results of two phase flow research such as coverage of fuel cells technology.

  20. Now entering phase two...

    CERN Multimedia

    Katarina Anthony

    2012-01-01

    Building on the success of their feasibility phase, the CLIC test facility, CTF3, has just launched into a five-year project development phase. This will involve detailed performance optimisation studies, marking the project’s transition from pure research and development to prototyping and construction.   CLIC accelerator modules under construction at CERN. “With the feasibility phase now complete, we have established that CLIC can be built,” says Roberto Corsini, CLIC Collaboration spokesperson. “Now we want to be sure that it can provide the luminosity and energy performance needed. We will be looking at the engineering, performance and cost of a real CLIC machine also seeing if we can reduce it.” CTF3’s second phase will focus on selected performance-related research areas for further investigation. The largest of these involves the construction and testing of several authentic CLIC accelerator modules that are currently being ...

  1. B1-B2 phase transition mechanism and pathway of PbS under pressure

    Science.gov (United States)

    Adeleke, Adebayo A.; Yao, Yansun

    2018-03-01

    Experimental studies at finite Pressure-Temperature (P-T) conditions and a theoretical study at 0 K of the phase transition in lead sulphide (PbS) have been inconclusive. Many studies that have been done to understand structural transformation in PbS can broadly be classified into two main ideological streams—one with Pnma and another with Cmcm orthorhombic intermediate phase. To foster better understanding of this phenomenon, we present the result of the first-principles study of phase transition in PbS at finite temperature. We employed the particle swarm-intelligence optimization algorithm for the 0 K structure search and first-principles metadynamics simulations to study the phase transition pathway of PbS from the ambient pressure, 0 K Fm-3m structure to the high-pressure Pm-3m phase under experimentally achievable P-T conditions. Significantly, our calculation shows that both streams are achievable under specific P-T conditions. We further uncover new tetragonal and monoclinic structures of PbS with space group P21/c and I41/amd, respectively. We propose the P21/c and I41/amd as a precursor phase to the Pnma and Cmcm phases, respectively. We investigated the stability of the new structures and found them to be dynamically stable at their stability pressure range. Electronic structure calculations reveal that both P21/c and I41/amd phases are semiconducting with direct and indirect bandgap energies of 0.69(5) eV and 0.97(3) eV, respectively. In general, both P21/c and I41/amd phases were found to be energetically competitive with their respective orthorhombic successors.

  2. Ductile fracture of two-phase welds under 77K. [Steel-EhP810, steel-EhP666, steel-08Kh18N10T, steel-EhP659-VI, steel-chP810

    Energy Technology Data Exchange (ETDEWEB)

    Yushchenko, K.A.; Voronin, S.A.; Pustovit, A.I.; Shavel' , A.V.

    The effect of the type of welding and fillers on crack resistance of welded joints high-strength steel EhP810 and its various compounds with steels EhP666, 08Kh18N10T has been studied. For the welding of steel EhP810 with steels EhP810, EhP666, 08Kh18N10T electron-beam, automatic, argon tungsten arc with non-consumable electrode with various fillers, as well as argon metal-arc welding with consumable electrode, were used. It is shown, that for a joint, made by electron-beam welding, parameters sigmasub(u), Ksub(IcJ), KCV are higher than for a joint of a similar phase structure made using filler wire EhP659-VI. It is explained by the fact, that during electron-beam welding joint metal refining takes place, which removes gases. In welded joints of chP810 steel, having joints with austenitic structure, characteristic of crack resistance Ssub(c) increases by more than 0.2 mm in contrast to two-phase joints, which conventional yield strength at 77 K exceeds 1000 MPa. It is worth mentioning, that for other classes of steels formation of two-phase structure of joint increases welded joint resistance to brittle fracture. It is possible to obtain the required structure of joint with assigned level of resistance to brittle fracture by means of the use of different fillers, optimum and welding procedure, regulating the part of the basic metal in joint content.

  3. Treatment-related death in patients with small-cell lung cancer in phase III trials over the last two decades.

    Directory of Open Access Journals (Sweden)

    Nobuaki Ochi

    Full Text Available INTRODUCTION: Treatment-related death (TRD remains a serious problem in small-cell lung cancer (SCLC, despite recent improvements in supportive care. However, few studies have formally assessed time trends in the proportion of TRD over the past two decades. The aim of this study was to determine the frequency and pattern of TRD over time. METHODS: We examined phase 3 trials conducted between 1990 and 2010 to address the role of systemic treatment for SCLC. The time trend was assessed using linear regression analysis. RESULTS: In total, 97 trials including nearly 25,000 enrolled patients were analyzed. The overall TRD proportion was 2.95%. Regarding the time trend, while it was not statistically significant, it tended to decrease, with a 0.138% decrease per year and 2.76% decrease per two decades. The most common cause of death was febrile neutropenia without any significant time trend in its incidence over the years examined (p = 0.139. However, deaths due to febrile neutropenia as well as all causes in patients treated with non-platinum chemotherapy increased significantly (p = 0.033. CONCLUSIONS: The overall TRD rate has been low, but not negligible, in phase III trials for SCLC over the past two decades.

  4. Development of New Correlation and Assessment of Correlations for Two-Phase Pressure Drop in Rectangular Microchannels

    International Nuclear Information System (INIS)

    Choi, Chi Woong; Yu, Dong In; Kim, Moo Hwan

    2010-01-01

    There are two kinds of models in two-phase pressured drop; homogeneous flow model and separated flow model. Many previous researchers have developed correlations for two-phase pressure drop in a microchannel. Most correlations were modified Lockhart and Martinelli's correlation, which was based on the separated flow model. In this study, experiments for adiabatic liquid water and nitrogen gas flow in rectangular microchannels were conducted to investigate two-phase pressure drop in the rectangular microchannels. Two-phase frictional pressure drop in the rectangular microchannels is highly related with flow regime. Homogeneous model with six two-phase viscosity models: Owen(21)'s, MacAdams(22)'s, Cicchitti et al.(23)'s, Dukler et al.(24)'s, Beattie and Whalley(25)'s, Lin et al.(26)'s models and six separated flow models: Lockhart and Martinelli(27)'s, Chisholm(31)'s, Zhang et al.(15)'s, Lee and Lee(5)'s, Moriyama and Inue(4)'s, Qu and Mudawar(8)'s models were assessed with our experimental data. The best two-phase viscosity model is Beattie and Whalley's model. The best separated flow model is Qu and Mudawar's correlation. Flow regime dependency in both homogeneous and separated flow models was observed. Therefore, new flow pattern based correlations for both homogeneous and separated flow models were individually proposed

  5. Phase separation and pressure drop of two-phase flow in vertical manifolds

    International Nuclear Information System (INIS)

    Zetzmann, K.

    1982-01-01

    The splitting of a two-phase mass flow in a tube manifold results in a separation between liquid and gas phase. A study is presented of the phase distribution and the related two-phase pressure drop for vertical manifolds in the technically relevant geometry and flow parameter region of an air-water-flow. At the outlet changes in the gas/fluid-radio are observed which are proportional to this ratio at the inlet. The separation characteristic strongly depends on the massflow through the junction. Empirical equations are given to calculate the separation. Measuring the pressure drop at main- and secondary tube of the manifold the additional pressure drop can be obtained. If these results are related with the dynamic pressure at the inlet, two-phase resistance coefficients can be deduced, which may be tested by empirical relations. (orig.) [de

  6. GADD45a Regulates Olaquindox-Induced DNA Damage and S-Phase Arrest in Human Hepatoma G2 Cells via JNK/p38 Pathways

    Directory of Open Access Journals (Sweden)

    Daowen Li

    2017-01-01

    Full Text Available Olaquindox, a quinoxaline 1,4-dioxide derivative, is widely used as a feed additive in many countries. The potential genotoxicity of olaquindox, hence, is of concern. However, the proper mechanism of toxicity was unclear. The aim of the present study was to investigate the effect of growth arrest and DNA damage 45 alpha (GADD45a on olaquindox-induced DNA damage and cell cycle arrest in HepG2 cells. The results showed that olaquindox could induce reactive oxygen species (ROS-mediated DNA damage and S-phase arrest, where increases of GADD45a, cyclin A, Cdk 2, p21 and p53 protein expression, decrease of cyclin D1 and the activation of phosphorylation-c-Jun N-terminal kinases (p-JNK, phosphorylation-p38 (p-p38 and phosphorylation-extracellular signal-regulated kinases (p-ERK were involved. However, GADD45a knockdown cells treated with olaquindox could significantly decrease cell viability, exacerbate DNA damage and increase S-phase arrest, associated with the marked activation of p-JNK, p-p38, but not p-ERK. Furthermore, SP600125 and SB203580 aggravated olaquindox-induced DNA damage and S-phase arrest, suppressed the expression of GADD45a. Taken together, these findings revealed that GADD45a played a protective role in olaquindox treatment and JNK/p38 pathways may partly contribute to GADD45a regulated olaquindox-induced DNA damage and S-phase arrest. Our findings increase the understanding on the molecular mechanisms of olaquindox.

  7. Measurement of the relative yields of ψ (2 S ) to ψ (1 S ) mesons produced at forward and backward rapidity in p +p , p +Al , p +Au , and 3He+Au collisions at √{sNN}=200 GeV

    Science.gov (United States)

    Adare, A.; Aidala, C.; Ajitanand, N. N.; Akiba, Y.; Alfred, M.; Andrieux, V.; Aoki, K.; Apadula, N.; Asano, H.; Ayuso, C.; Azmoun, B.; Babintsev, V.; Bai, M.; Bandara, N. S.; Bannier, B.; Barish, K. N.; Bathe, S.; Bazilevsky, A.; Beaumier, M.; Beckman, S.; Belmont, R.; Berdnikov, A.; Berdnikov, Y.; Blau, D. S.; Boer, M.; Bok, J. S.; Bownes, E. K.; Boyle, K.; Brooks, M. L.; Bryslawskyj, J.; Bumazhnov, V.; Butler, C.; Campbell, S.; Canoa Roman, V.; Cervantes, R.; Chen, C.-H.; Chi, C. Y.; Chiu, M.; Choi, I. J.; Choi, J. B.; Chujo, T.; Citron, Z.; Connors, M.; Cronin, N.; Csanád, M.; Csörgő, T.; Danley, T. W.; Datta, A.; Daugherity, M. S.; David, G.; Deblasio, K.; Dehmelt, K.; Denisov, A.; Deshpande, A.; Desmond, E. J.; Dion, A.; Diss, P. B.; Dixit, D.; Do, J. H.; Drees, A.; Drees, K. A.; Dumancic, M.; Durham, J. M.; Durum, A.; Dusing, J. P.; Elder, T.; Enokizono, A.; En'yo, H.; Esumi, S.; Fadem, B.; Fan, W.; Feege, N.; Fields, D. E.; Finger, M.; Finger, M.; Fokin, S. L.; Frantz, J. E.; Franz, A.; Frawley, A. D.; Fukuda, Y.; Gal, C.; Gallus, P.; Garg, P.; Ge, H.; Giordano, F.; Glenn, A.; Goto, Y.; Grau, N.; Greene, S. V.; Grosse Perdekamp, M.; Gunji, T.; Guragain, H.; Hachiya, T.; Haggerty, J. S.; Hahn, K. I.; Hamagaki, H.; Hamilton, H. F.; Han, S. Y.; Hanks, J.; Hasegawa, S.; Haseler, T. O. S.; Hashimoto, K.; He, X.; Hemmick, T. K.; Hill, J. C.; Hill, K.; Hollis, R. S.; Homma, K.; Hong, B.; Hoshino, T.; Hotvedt, N.; Huang, J.; Huang, S.; Imai, K.; Imrek, J.; Inaba, M.; Iordanova, A.; Isenhower, D.; Ito, Y.; Ivanishchev, D.; Jacak, B. V.; Jezghani, M.; Ji, Z.; Jia, J.; Jiang, X.; Johnson, B. M.; Jorjadze, V.; Jouan, D.; Jumper, D. S.; Kanda, S.; Kang, J. H.; Kapukchyan, D.; Karthas, S.; Kawall, D.; Kazantsev, A. V.; Key, J. A.; Khachatryan, V.; Khanzadeev, A.; Kim, C.; Kim, D. J.; Kim, E.-J.; Kim, G. W.; Kim, M.; Kimball, M. L.; Kimelman, B.; Kincses, D.; Kistenev, E.; Kitamura, R.; Klatsky, J.; Kleinjan, D.; Kline, P.; Koblesky, T.; Komkov, B.; Kotler, J. R.; Kotov, D.; Kudo, S.; Kurita, K.; Kurosawa, M.; Kwon, Y.; Lacey, R.; Lajoie, J. G.; Lallow, E. O.; Lebedev, A.; Lee, S.; Lee, S. H.; Leitch, M. J.; Leung, Y. H.; Lewis, N. A.; Li, X.; Li, X.; Lim, S. H.; Liu, L. D.; Liu, M. X.; Loggins, V.-R.; Loggins, V.-R.; Lovasz, K.; Lynch, D.; Majoros, T.; Makdisi, Y. I.; Makek, M.; Malaev, M.; Manion, A.; Manko, V. I.; Mannel, E.; Masuda, H.; McCumber, M.; McGaughey, P. L.; McGlinchey, D.; McKinney, C.; Meles, A.; Mendez, A. R.; Mendoza, M.; Mignerey, A. C.; Mihalik, D. E.; Milov, A.; Mishra, D. K.; Mitchell, J. T.; Mitsuka, G.; Miyasaka, S.; Mizuno, S.; Mohanty, A. K.; Montuenga, P.; Moon, T.; Morrison, D. P.; Morrow, S. I. M.; Moukhanova, T. V.; Murakami, T.; Murata, J.; Mwai, A.; Nagai, K.; Nagashima, K.; Nagashima, T.; Nagle, J. L.; Nagy, M. I.; Nakagawa, I.; Nakagomi, H.; Nakano, K.; Nattrass, C.; Netrakanti, P. K.; Niida, T.; Nishimura, S.; Nouicer, R.; Novák, T.; Novitzky, N.; Novotny, R.; Nyanin, A. S.; O'Brien, E.; Ogilvie, C. A.; Orjuela Koop, J. D.; Osborn, J. D.; Oskarsson, A.; Ottino, G. J.; Ozawa, K.; Pak, R.; Pantuev, V.; Papavassiliou, V.; Park, J. S.; Park, S.; Pate, S. F.; Patel, M.; Peng, J.-C.; Peng, W.; Perepelitsa, D. V.; Perera, G. D. N.; Peressounko, D. Yu.; Perezlara, C. E.; Perry, J.; Petti, R.; Phipps, M.; Pinkenburg, C.; Pinson, R.; Pisani, R. P.; Press, C. J.; Pun, A.; Purschke, M. L.; Rak, J.; Ramson, B. J.; Ravinovich, I.; Read, K. F.; Reynolds, D.; Riabov, V.; Riabov, Y.; Richford, D.; Rinn, T.; Rolnick, S. D.; Rosati, M.; Rowan, Z.; Rubin, J. G.; Runchey, J.; Safonov, A. S.; Sahlmueller, B.; Saito, N.; Sakaguchi, T.; Sako, H.; Samsonov, V.; Sarsour, M.; Sato, K.; Sato, S.; Schaefer, B.; Schmoll, B. K.; Sedgwick, K.; Seidl, R.; Sen, A.; Seto, R.; Sett, P.; Sexton, A.; Sharma, D.; Shein, I.; Shibata, T.-A.; Shigaki, K.; Shimomura, M.; Shioya, T.; Shukla, P.; Sickles, A.; Silva, C. L.; Silva, J. A.; Silvermyr, D.; Singh, B. K.; Singh, C. P.; Singh, V.; Slunečka, M.; Smith, K. L.; Snowball, M.; Soltz, R. A.; Sondheim, W. E.; Sorensen, S. P.; Sourikova, I. V.; Stankus, P. W.; Stepanov, M.; Stien, H.; Stoll, S. P.; Sugitate, T.; Sukhanov, A.; Sumita, T.; Sun, J.; Syed, S.; Sziklai, J.; Takeda, A.; Taketani, A.; Tanida, K.; Tannenbaum, M. J.; Tarafdar, S.; Taranenko, A.; Tarnai, G.; Tieulent, R.; Timilsina, A.; Todoroki, T.; Tomášek, M.; Towell, C. L.; Towell, R.; Towell, R. S.; Tserruya, I.; Ueda, Y.; Ujvari, B.; van Hecke, H. W.; Vazquez-Carson, S.; Velkovska, J.; Virius, M.; Vrba, V.; Vukman, N.; Wang, X. R.; Wang, Z.; Watanabe, Y.; Watanabe, Y. S.; Wei, F.; White, A. S.; Wong, C. P.; Woody, C. L.; Wysocki, M.; Xia, B.; Xu, C.; Xu, Q.; Xue, L.; Yalcin, S.; Yamaguchi, Y. L.; Yamamoto, H.; Yanovich, A.; Yin, P.; Yoo, J. H.; Yoon, I.; Yu, H.; Yushmanov, I. E.; Zajc, W. A.; Zelenski, A.; Zharko, S.; Zhou, S.; Zou, L.; Phenix Collaboration

    2017-03-01

    The PHENIX Collaboration has measured the ratio of the yields of ψ (2 S ) to ψ (1 S ) mesons produced in p +p , p +Al , p +Au , and 3He+Au collisions at √{s NN}=200 GeV over the forward and backward rapidity intervals 1.2 <|y |<2.2 . We find that the ratio in p +p collisions is consistent with measurements at other collision energies. In collisions with nuclei, we find that in the forward (p -going or 3He-going) direction, the relative yield of ψ (2 S ) mesons to ψ (1 S ) mesons is consistent with the value measured in p +p collisions. However, in the backward (nucleus-going) direction, the ψ (2 S ) meson is preferentially suppressed by a factor of ˜2 . This suppression is attributed in some models to the breakup of the weakly bound ψ (2 S ) meson through final-state interactions with comoving particles, which have a higher density in the nucleus-going direction. These breakup effects may compete with color screening in a deconfined quark-gluon plasma to produce sequential suppression of excited quarkonia states.

  8. Dynamic Modeling of Phase Crossings in Two-Phase Flow

    DEFF Research Database (Denmark)

    Madsen, Søren; Veje, Christian; Willatzen, Morten

    2012-01-01

    by a high resolution finite difference scheme due to Kurganov and Tadmore. The homogeneous formulation requires a set of thermodynamic relations to cover the entire range from liquid to gas state. This leads a number of numerical challenges since these relations introduce discontinuities in the derivative...... of the variables and are usually very slow to evaluate. To overcome these challenges, we use an interpolation scheme with local refinement. The simulations show that the method handles crossing of the saturation lines for both liquid to two-phase and two-phase to gas regions. Furthermore, a novel result obtained...

  9. The Re-Mo-S system: New data on phase relations between 400 and 1200 °C

    Czech Academy of Sciences Publication Activity Database

    Drábek, M.; Rieder, M.; Böhmová, Vlasta

    2010-01-01

    Roč. 22, č. 4 (2010), s. 479-484 ISSN 0935-1221 Institutional research plan: CEZ:AV0Z30130516 Keywords : phase relations * Re–Mo–S system, * molybdenite * rheniite * Re * Mo * S Subject RIV: DB - Geology ; Mineralogy Impact factor: 1.469, year: 2010

  10. Two-phase pressure drop and heat transfer of sodium at forced convection

    International Nuclear Information System (INIS)

    Grieb, G.

    1989-04-01

    Experiments with sodium for the two-phase pressure drop in vertical tubes with upward flow (internal diameters 6 and 9 mm) performed at the Joint Research Centre (JRC) of the European Communities in Ispra, Italy, and at the Nuclear Research Centre in Karlsruhe (KfK) were evaluated and analysed. Furthermore, experiments for the single-phase and two-phase heat transfer in the grid spaced twelve-rod bundle (p d /d =1.3, rod diameter 8 mm) with flow in axial direction performed at the JRC were evaluated and analysed. The pressure drop measurements were carried out at moderate to high mass flow rates (30 to 4500 kg/(m 2 s)) and at moderate pressures (50 to 300 kPa, density ratio ρ f /ρ g = 950 to 5400). The measurements for the single-phase heat transfer at high heat fluxes (0.16 to 1.6 MW/m 2 ) were carried out in the Reynolds number region (3100 2 s)) and at high heat fluxes (0.46 to 1.6 MW/m 2 ) within the temperature range from 870 to 970 0 C. For the subsequent calculation of the experiments relating to the two-phase pressure drop a computer program was developed, which is based on the so-called slip model. It requires a friction pressure loss correlation and a slip correlation. The tested correlations were not suitable for describing the experimental measurements. Accordingly, simplified equations of momentum were used to develop a new slip correlation for the case of annular flow together with the annular-mist flow, the most important two-phase flow regimes for sodium in the measurement range. After the inception of the entrainment - transition from the annular flow to the annular-mist flow - an even larger fraction of liquid enters the vapour core in the form of droplets, as the vapour quality increases. An equation was formulated for the slip in this region and adapted to the experiments via coefficients. (orig./GL) [de

  11. Probabilistic physical characteristics of phase transitions at highway bottlenecks: incommensurability of three-phase and two-phase traffic-flow theories.

    Science.gov (United States)

    Kerner, Boris S; Klenov, Sergey L; Schreckenberg, Michael

    2014-05-01

    Physical features of induced phase transitions in a metastable free flow at an on-ramp bottleneck in three-phase and two-phase cellular automaton (CA) traffic-flow models have been revealed. It turns out that at given flow rates at the bottleneck, to induce a moving jam (F → J transition) in the metastable free flow through the application of a time-limited on-ramp inflow impulse, in both two-phase and three-phase CA models the same critical amplitude of the impulse is required. If a smaller impulse than this critical one is applied, neither F → J transition nor other phase transitions can occur in the two-phase CA model. We have found that in contrast with the two-phase CA model, in the three-phase CA model, if the same smaller impulse is applied, then a phase transition from free flow to synchronized flow (F → S transition) can be induced at the bottleneck. This explains why rather than the F → J transition, in the three-phase theory traffic breakdown at a highway bottleneck is governed by an F → S transition, as observed in real measured traffic data. None of two-phase traffic-flow theories incorporates an F → S transition in a metastable free flow at the bottleneck that is the main feature of the three-phase theory. On the one hand, this shows the incommensurability of three-phase and two-phase traffic-flow theories. On the other hand, this clarifies why none of the two-phase traffic-flow theories can explain the set of fundamental empirical features of traffic breakdown at highway bottlenecks.

  12. [Role and related mechanism of S1P/S1P1 signal pathway during post conditioning of hypertrophic cardiomyocytes].

    Science.gov (United States)

    Bao, X H; Li, H X; Tao, J; Li, X M; Yang, Y N; Ma, Y T; Chen, B D

    2016-05-24

    To study the role and mechanism of sphingosine-1-phosphate (S1P)/ sphingosine-1-phosphate receptor 1(S1P1) signal pathway during post conditioning of hypertrophic cardiomyocytes. Neonatal rat cardiomyocytes were isolated and cultured, then stimulated by norepinephrine (NE) to induce cardiomyocytes hypertrophy. Using tri-gas incubator to create hypoxia and reoxygenation enviroment to mimic ischemia-reperfusion and postconditioning. Hypertrophic cardiomyoctyes were divided into five groups according to the presence or absence of various drugs and postconditiong and relevant signal pathways changes were detected: (1) IPost group (hypoxia+ postconditioning); (2) IPost+ S1P group (cells were pretreated with S1P (1 μmol/L) for 2 h before IPost); (3) IPost+ W-146+ S1P group (cells in IPost+ W-146+ S1P group were pretreated with S1P1 inhibitor W-146 (0.4 μmol/L) for 20 min); (4) IPost+ PD98059+ S1P group (cells in IPost+ S1P group were pretreated with MAPK antagonist PD98059 (125 μmol/L) for 20 min); (5) IPost+ LY-294002+ S1P group (cells in IPost+ S1P group were pretreated with PI3K antagonist LY294002 (0.1 μmol/L) for 20 min). Apoptosis was detected by flow cytometry and protein expression of relevant signal pathways were detected by Western blot. (1)Apoptosis rate was significantly increased in hypoxia/reoxygenation (27.90±4.49)% group compared with normal control group (7.97±2.18)%, which could be significantly reduced in IPost group (15.90±1.77)% (all PS1P and IPost+ S1P+ LY-294002 groups than in IPost and IPost+ S1P+ W-146 and IPost+ S1P+ PD98059 group (all PS1P and IPost+ S1P+ LY-294002 group than in IPost and IPost+ S1P+ W-146 group and IPost+ S1P+ PD98059 group (all PS1P+ W-146 and IPost+ S1P+ PD98059 groups. p-ERK1/2 and p-Akt levels in IPost+ S1P+ W-146 group and IPost+ S1P+ PD98059 were similar as in IPost group. S1P can play protective role on NE induced cardiomyocytes hypertrophy during post conditioning through downregulating caspase-3 expression and

  13. The Effect of Wettability Heterogeneity on Relative Permeability of Two-Phase Flow in Porous Media: A Lattice Boltzmann Study

    Science.gov (United States)

    Zhao, Jianlin; Kang, Qinjun; Yao, Jun; Viswanathan, Hari; Pawar, Rajesh; Zhang, Lei; Sun, Hai

    2018-02-01

    Relative permeability is a critical parameter characterizing multiphase flow in porous media and it is strongly dependent on the wettability. In many situations, the porous media are nonuniformly wet. To investigate the effect of wettability heterogeneity on relative permeability of two-phase flow in porous media, a multi-relaxation-time color-gradient lattice Boltzmann model is adopted to simulate oil/water two-phase flow in porous media with different oil-wet solid fractions. For the water phase, when the water saturation is high, the relative permeability of water increases with the increase of oil-wet solid fraction under a constant water saturation. However, as the water saturation decreases to an intermediate value (about 0.4-0.7), the relative permeability of water in fractionally wet porous media could be lower than that in purely water-wet porous media, meaning additional flow resistance exists in the fractionally wet porous media. For the oil phase, similar phenomenon is observed. This phenomenon is mainly caused by the wettability-related microscale fluid distribution. According to both our simulation results and theoretical analysis, it is found that the relative permeability of two-phase flow in porous media is strongly related to three parameters: the fluid saturation, the specific interfacial length of fluid, and the fluid tortuosity in the flow direction. The relationship between the relative permeability and these parameters under different capillary numbers is explored in this paper.

  14. Analysis of phase dynamics in two-phase flow using latticegas automata

    International Nuclear Information System (INIS)

    Ohashi, H.; Hashimoto, Y.; Tsumaya, A.; Chen, Y.; Akiyama, M.

    1998-01-01

    In this paper, we describe lattice gas automaton models appropriate for two-phase flow simulation and their applications to study various phase dynamics of two-fluid mixtures. Several algorithms are added to the original immiscible Lattice Gas model to adjust surface tension and to introduce density difference between two fluids. Surface tension is controlled by the collision rules an difference in density is due to nonlocal forces between automaton particles. We simulate the relative motion of the dispersed phase in another continuous fluid. Deformation and disintegration of rising drops are reproduced. The interaction between multiple drops is also observed in calculations. Furutre, we obtain the transition of the two-phase flow pattern from bubbly, slug to annular flow. Density difference of two phase is one of the key ingredients to generate the annular flow pattern

  15. Hyperoxia-induced p47phox activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P1&2 signaling axis in lung endothelium.

    Science.gov (United States)

    Harijith, Anantha; Pendyala, Srikanth; Ebenezer, David L; Ha, Alison W; Fu, Panfeng; Wang, Yue-Ting; Ma, Ke; Toth, Peter T; Berdyshev, Evgeny V; Kanteti, Prasad; Natarajan, Viswanathan

    2016-08-01

    Hyperoxia-induced lung injury adversely affects ICU patients and neonates on ventilator assisted breathing. The underlying culprit appears to be reactive oxygen species (ROS)-induced lung damage. The major contributor of hyperoxia-induced ROS is activation of the multiprotein enzyme complex NADPH oxidase. Sphingosine-1-phosphate (S1P) signaling is known to be involved in hyperoxia-mediated ROS generation; however, the mechanism(s) of S1P-induced NADPH oxidase activation is unclear. Here, we investigated various steps in the S1P signaling pathway mediating ROS production in response to hyperoxia in lung endothelium. Of the two closely related sphingosine kinases (SphKs)1 and 2, which synthesize S1P from sphingosine, only Sphk1(-/-) mice conferred protection against hyperoxia-induced lung injury. S1P is metabolized predominantly by S1P lyase and partial deletion of Sgpl1 (Sgpl1(+/-)) in mice accentuated lung injury. Hyperoxia stimulated S1P accumulation in human lung microvascular endothelial cells (HLMVECs), and downregulation of S1P transporter spinster homolog 2 (Spns2) or S1P receptors S1P1&2, but not S1P3, using specific siRNA attenuated hyperoxia-induced p47(phox) translocation to cell periphery and ROS generation in HLMVECs. These results suggest a role for Spns2 and S1P1&2 in hyperoxia-mediated ROS generation. In addition, p47(phox) (phox:phagocyte oxidase) activation and ROS generation was also reduced by PF543, a specific SphK1 inhibitor in HLMVECs. Our data indicate a novel role for Spns2 and S1P1&2 in the activation of p47(phox) and production of ROS involved in hyperoxia-mediated lung injury in neonatal and adult mice. Copyright © 2016 the American Physiological Society.

  16. Two-phase semilinear free boundary problem with a degenerate phase

    KAUST Repository

    Matevosyan, Norayr

    2010-10-16

    We study minimizers of the energy functional ∫D[{pipe}∇u{pipe}2 + λ(u+)p]dx for p ∈ (0, 1) without any sign restriction on the function u. The distinguished feature of the problem is the lack of nondegeneracy in the negative phase. The main result states that in dimension two the free boundaries Γ+ = ∂{u > 0} ∩ D andΓ- = ∂{u < 0} ∩ D are C1,α-regular, provided 1 - ∈0 < p < 1. The proof is obtained by a careful iteration of the Harnack inequality to obtain a nontrivial growth estimate in the negative phase, compensating for the apriori unknown nondegeneracy. © 2010 Springer-Verlag.

  17. Blocking S1P interaction with S1P1 receptor by a novel competitive S1P1-selective antagonist inhibits angiogenesis

    International Nuclear Information System (INIS)

    Fujii, Yasuyuki; Ueda, Yasuji; Ohtake, Hidenori; Ono, Naoya; Takayama, Tetsuo; Nakazawa, Kiyoshi; Igarashi, Yasuyuki; Goitsuka, Ryo

    2012-01-01

    Highlights: ► The effect of a newly developed S1P 1 -selective antagonist on angiogenic responses. ► S1P 1 is a critical component of VEGF-related angiogenic responses. ► S1P 1 -selective antagonist showed in vitro activity to inhibit angiogenesis. ► S1P 1 -selective antagonist showed in vivo activity to inhibit angiogenesis. ► The efficacy of S1P 1 -selective antagonist for anti-cancer therapies. -- Abstract: Sphingosine 1-phosphate receptor type 1 (S1P 1 ) was shown to be essential for vascular maturation during embryonic development and it has been demonstrated that substantial crosstalk exists between S1P 1 and other pro-angiogenic growth factors, such as vascular endothelial growth factor (VEGF) and basic fibroblast growth factor. We developed a novel S1P 1 -selective antagonist, TASP0277308, which is structurally unrelated to S1P as well as previously described S1P 1 antagonists. TASP0277308 inhibited S1P- as well as VEGF-induced cellular responses, including migration and proliferation of human umbilical vein endothelial cells. Furthermore, TASP0277308 effectively blocked a VEGF-induced tube formation in vitro and significantly suppressed tumor cell-induced angiogenesis in vivo. These findings revealed that S1P 1 is a critical component of VEGF-related angiogenic responses and also provide evidence for the efficacy of TASP0277308 for anti-cancer therapies.

  18. Cytotoxicity of InP/ZnS quantum dots related to reactive oxygen species generation

    Science.gov (United States)

    Chibli, Hicham; Carlini, Lina; Park, Soonhyang; Dimitrijevic, Nada M.; Nadeau, Jay L.

    2011-06-01

    Indium phosphide (InP) quantum dots (QDs) have emerged as a presumably less hazardous alternative to cadmium-based particles, but their cytotoxicity has not been well examined. Although their constituent elements are of very low toxicity to cells in culture, they nonetheless exhibit phototoxicity related to generation of reactive oxygen species by excited electrons and/or holes interacting with water and molecular oxygen. Using spin-trap electron paramagnetic resonance (EPR) spectroscopy and reporter assays, we find a considerable amount of superoxide and a small amount of hydroxyl radical formed under visible illumination of biocompatible InP QDs with a single ZnS shell, comparable to what is seen with CdTe. A double thickness shell reduces the reactive oxygen species concentration approximately two-fold. Survival assays in five cell lines correspondingly indicate a distinct reduction in toxicity with the double-shell InP QDs. Toxicity varies significantly across cell lines according to the efficiency of uptake, being overall significantly less than what is seen with CdTe or CdSe/ZnS. This indicates that InP QDs are a useful alternative to cadmium-containing QDs, while remaining capable of electron-transfer processes that may be undesirable or which may be exploited for photosensitization applications.

  19. Cytotoxicity of InP/ZnS quantum dots related to reactive oxygen species generation.

    Energy Technology Data Exchange (ETDEWEB)

    Chibli, H.; Carlini, L.; Park, S.; Dimitrijevic, N. M.; Nadeau, J. L. (Center for Nanoscale Materials); ( CSE); (McGill Univ.)

    2011-01-01

    Indium phosphide (InP) quantum dots (QDs) have emerged as a presumably less hazardous alternative to cadmium-based particles, but their cytotoxicity has not been well examined. Although their constituent elements are of very low toxicity to cells in culture, they nonetheless exhibit phototoxicity related to generation of reactive oxygen species by excited electrons and/or holes interacting with water and molecular oxygen. Using spin-trap electron paramagnetic resonance (EPR) spectroscopy and reporter assays, we find a considerable amount of superoxide and a small amount of hydroxyl radical formed under visible illumination of biocompatible InP QDs with a single ZnS shell, comparable to what is seen with CdTe. A double thickness shell reduces the reactive oxygen species concentration approximately two-fold. Survival assays in five cell lines correspondingly indicate a distinct reduction in toxicity with the double-shell InP QDs. Toxicity varies significantly across cell lines according to the efficiency of uptake, being overall significantly less than what is seen with CdTe or CdSe/ZnS. This indicates that InP QDs are a useful alternative to cadmium-containing QDs, while remaining capable of electron-transfer processes that may be undesirable or which may be exploited for photosensitization applications.

  20. Telomerase and Tel1p Preferentially Associate with Short Telomeres in S. cerevisiae

    Science.gov (United States)

    Sabourin, Michelle; Tuzon, Creighton T.; Zakian, Virginia A.

    2009-01-01

    SUMMARY In diverse organisms, telomerase preferentially elongates short telomeres. We generated a single short telomere in otherwise wild-type (WT) S. cerevisiae cells. The binding of the positive regulators Ku and Cdc13p was similar at short and WT-length telomeres. The negative regulators Rif1p and Rif2p were present at the short telomere, although Rif2p levels were reduced. Two telomerase holoenzyme components, Est1p and Est2p, were preferentially enriched at short telomeres in late S/G2 phase, the time of telomerase action. Tel1p, the yeast ATM-like checkpoint kinase, was highly enriched at short telomeres from early S through G2 phase and even into the next cell cycle. Nonetheless, induction of a single short telomere did not elicit a cell-cycle arrest. Tel1p binding was dependent on Xrs2p and required for preferential binding of telomerase to short telomeres. These data suggest that Tel1p targets telomerase to the DNA ends most in need of extension. PMID:17656141

  1. Film boiling from spheres in single- and two-phase flow

    International Nuclear Information System (INIS)

    Liu, C.; Theofanous, T.G.; Yuen, W.W.

    1992-01-01

    Experimental data on film boiling heat transfer from single, inductively heated, spheres in single- and two-phase flow (saturated water and steam, respectively) are presented. In the single-phase-flow experiments water velocities ranged from 0.1 to 2.0 m/s; in the two-phase-flow experiments superficial water and steam velocities covered 0.1 to 0.6 m/s and 4 to 10 m/s, respectively. All experiments were run at atmospheric pressure and with sphere temperatures from 900C down to quenching. Limited interpretations of the single-phase- flow data are possible, but the two-phase-flow data are new and unique

  2. Nature of low dimensional structural modulations and relative phase stability in RexMo(W)1-xS2 transition metal dichalcogenide alloys

    KAUST Repository

    Sahu, R.

    2017-03-08

    We report on the various types of Peierls like two dimensional structural modulations and relative phase stability of 2H and 1T poly-types in the RexMo1-xS2 and RexW1-xS2 alloy system. Theoretical calculation predicts a polytype phase transition cross over at ∼50 at. % of Mo and W in ReS2 in both monolayer and bulk form, respectively. Experimentally, two different types of structural modulations at 50% and a modulation corresponding to trimerization at 75% alloy composition are observed for RexMo1-xS2 and only one type of modulation is observed at the 50% RexW1-xS2 alloy system. The 50% alloy system is found to be a suitable monolithic candidate for metal semiconductor transition with minute external perturbation. ReS2 is known to be in the 2D Peierls distorted 1Td structure and forms a chain like superstructure. Incorporation of Mo and W atoms into the ReS2 lattice modifies the metal-metal hybridization between the cations and influences the structural modulation and electronic properties of the system. The results offer yet another effective way to tune the electronic structure and poly-type phases of this class of materials other than intercalation, strain, and vertical stacking arrangement.

  3. Long-wave equivalent viscoelastic solids for porous rocks saturated by two-phase fluids

    Science.gov (United States)

    Santos, J. E.; Savioli, G. B.

    2018-04-01

    Seismic waves traveling across fluid-saturated poroelastic materials with mesoscopic-scale heterogeneities induce fluid flow and Biot's slow waves generating energy loss and velocity dispersion. Using Biot's equations of motion to model these type of heterogeneities would require extremely fine meshes. We propose a numerical upscaling procedure to determine the complex and frequency dependent P-wave and shear moduli of an effective viscoelastic medium long-wave equivalent to a poroelastic solid saturated by a two-phase fluid. The two-phase fluid is defined in terms of capillary pressure and relative permeability flow functions. The P-wave and shear effective moduli are determined using harmonic compressibility and shear experiments applied on representative samples of the bulk material. Each experiment is associated with a boundary value problem that is solved using the finite element method. Since a poroelastic solid saturated by a two-phase fluid supports the existence of two slow waves, this upscaling procedure allows to analyze their effect on the mesoscopic-loss mechanism in hydrocarbon reservoir formations. Numerical results show that a two-phase Biot medium model predicts higher attenuation than classic Biot models.

  4. Hydrodynamics of single- and two-phase flow in inclined rod arrays

    International Nuclear Information System (INIS)

    Todreas, N.E.

    1984-01-01

    Required inputs for thermal-hydraulic codes are constitutive relations for fluid-solid flow resistance, in single-phase flow, and interfacial momentum exchange (relative phase motion), in two-phase flow. An inclined rod array air-water experiment was constructed to study the hydrodynamics of multidimensional porous medium flow in rod arrays. Velocities, pressures, bubble distributions, and void fractions were measured in inline and rotational square rod arrays of P/d = 1.5, at 0, 30, 45, and 90 degree inclinations to the vertical flow direction. Constitutive models for single-phase flow resistance are reviewed, new comprehensive models developed, and an assessment with previously published and new data made. The principle of superimposing one-dimensional correlations proves successful for turbulent single-phase inclined flow. For bubbly two-phase yawed flow through incline rod arrays a new flow separation phenomena was observed and modeled. Bubbles of diameters significantly smaller than the rod diameter travel along the rod axis, while larger diameter bubbles move through the rod array gaps. The outcome is a flow separation not predictable with current interfacial momentum exchange models. This phenomenon was not observed in rotated square rod arrays. Current interfacial momentum exchange models were confirmed for this rod arrangement. Models for the two phase flow resistance multiplier for cross flow were reviewed and compared with data from cross and yawed flow rod arrays. Both drag and lift components of the multiplier were well predicted by the homogenous model. Other models reviewed overpredicted the data by a factor of two

  5. Low copulatory activity in selectively bred Sardinian alcohol-nonpreferring (sNP) relative to alcohol-preferring (sP) rats

    Science.gov (United States)

    Karlsson, Oskar; Colombo, Giancarlo

    2015-01-01

    Background There is a growing consensus that similar neural mechanisms are involved in the reinforcing properties of natural rewards, like food and sex, and drugs of abuse. Rat lines selectively bred for high and low oral alcohol intake and preference have been useful for understanding factors contributing to excessive alcohol intake and may constitute proper animal models for investigating the neurobiological basis of natural rewarding stimuli. Methods The present study evaluated copulatory behavior in alcohol and sexually naïve Sardinian alcohol-preferring (sP) and -nonpreferring (sNP) male rats in three consecutive copulatory behavior tests. Results The main finding was that, under the conditions used in this study, sNP rats were sexually inactive relative to sP rats. To gain more information about the sexual behavior in sP rats, Wistar rats were included as an external reference strain. Only minor differences between sP and Wistar rats were revealed. Conclusions The reason behind the low copulatory activity of sNP rats remains to be elucidated, but may in part be mediated by innate differences in brain transmitter systems. The comparison between sP and Wistar rats may also suggest that the inherent proclivity to excessive alcohol drinking in sP rats may mainly be dependent on its anxiolytic properties, as previously proposed, and not changes in the reward system. PMID:25728453

  6. Uniqueness of Specific Interfacial Area–Capillary Pressure–Saturation Relationship Under Non-Equilibrium Conditions in Two-Phase Porous Media Flow

    KAUST Repository

    Joekar-Niasar, Vahid

    2012-02-23

    The capillary pressure-saturation (P c-S w) relationship is one of the central constitutive relationships used in two-phase flow simulations. There are two major concerns regarding this relation. These concerns are partially studied in a hypothetical porous medium using a dynamic pore-network model called DYPOSIT, which has been employed and extended for this study: (a) P c-S w relationship is measured empirically under equilibrium conditions. It is then used in Darcy-based simulations for all dynamic conditions. This is only valid if there is a guarantee that this relationship is unique for a given flow process (drainage or imbibition) independent of dynamic conditions; (b) It is also known that P c-S w relationship is flow process dependent. Depending on drainage and imbibition, different curves can be achieved, which are referred to as "hysteresis". A thermodynamically derived theory (Hassanizadeh and Gray, Water Resour Res 29: 3389-3904, 1993a) suggests that, by introducing a new state variable, called the specific interfacial area (a nw, defined as the ratio of fluid-fluid interfacial area to the total volume of the domain), it is possible to define a unique relation between capillary pressure, saturation, and interfacial area. This study investigates these two aspects of capillary pressure-saturation relationship using a dynamic pore-network model. The simulation results imply that P c-S w relation not only depends on flow process (drainage and imbibition) but also on dynamic conditions for a given flow process. Moreover, this study attempts to obtain the first preliminary insights into the global functionality of capillary pressure-saturation-interfacial area relationship under equilibrium and non-equilibrium conditions and the uniqueness of P c-S w-a nw relationship. © 2012 The Author(s).

  7. S phase entry causes homocysteine-induced death while ataxia telangiectasia and Rad3 related protein functions anti-apoptotically to protect neurons.

    Science.gov (United States)

    Ye, Weizhen; Blain, Stacy W

    2010-08-01

    A major phenotype seen in neurodegenerative disorders is the selective loss of neurons due to apoptotic death and evidence suggests that inappropriate re-activation of cell cycle proteins in post-mitotic neurons may be responsible. To investigate whether reactivation of the G1 cell cycle proteins and S phase entry was linked with apoptosis, we examined homocysteine-induced neuronal cell death in a rat cortical neuron tissue culture system. Hyperhomocysteinaemia is a physiological risk factor for a variety of neurodegenerative diseases, including Alzheimer's disease. We found that in response to homocysteine treatment, cyclin D1, and cyclin-dependent kinases 4 and 2 translocated to the nucleus, and p27 levels decreased. Both cyclin-dependent kinases 4 and 2 regained catalytic activity, the G1 gatekeeper retinoblastoma protein was phosphorylated and DNA synthesis was detected, suggesting transit into S phase. Double-labelling immunofluorescence showed a 95% co-localization of anti-bromodeoxyuridine labelling with apoptotic markers, demonstrating that those cells that entered S phase eventually died. Neurons could be protected from homocysteine-induced death by methods that inhibited G1 phase progression, including down-regulation of cyclin D1 expression, inhibition of cyclin-dependent kinases 4 or 2 activity by small molecule inhibitors, or use of the c-Abl kinase inhibitor, Gleevec, which blocked cyclin D and cyclin-dependent kinase 4 nuclear translocation. However, blocking cell cycle progression post G1, using DNA replication inhibitors, did not prevent apoptosis, suggesting that death was not preventable post the G1-S phase checkpoint. While homocysteine treatment caused DNA damage and activated the DNA damage response, its mechanism of action was distinct from that of more traditional DNA damaging agents, such as camptothecin, as it was p53-independent. Likewise, inhibition of the DNA damage sensors, ataxia-telangiectasia mutant and ataxia telangiectasia and Rad

  8. Reliable measurement of the Li-like 2248Ti 1s2s2p 4P5/2o level lifetime by beam-foil and beam-two-foil experiments

    International Nuclear Information System (INIS)

    Nandi, T.; Ahmad, Nissar; Wani, A. A.; Marketos, P.

    2006-01-01

    We have determined the lifetime of the Li-like 22 48 Ti 1s2s2p 4 P 5/2 o level (210.5±13.5 ps) using data from its x-ray decay channel through beam single- and two-foil experiments, coupled to a multicomponent iterative growth and decay analysis. Theoretical lifetime estimates for this zero-nuclear-spin ion lies within the uncertainty range of our experimental results, indicating that blending contributions to this level from the He-like 1s2p 3 P 2 o and 1s2s 3 S 1 levels are eliminated within the current approach. A previously reported discrepancy between experimental and theoretical 1s2s2p 4 P 5/2 o level lifetimes in 23 51 V may, as a result, be attributed to hyperfine quenching

  9. Thermodynamic evaluation of Cu-H-O-S-P system - Phase stabilities and solubilities for OFP-copper

    International Nuclear Information System (INIS)

    Magnusson, Hans; Frisk, Karin

    2013-04-01

    A thermodynamic evaluation for Cu-H-O-S-P has been made, with special focus on the phase stabilities and solubilities for OFP-copper. All binary systems including copper have been reviewed. Gaseous species and stoichiometric crystalline phases have been included for higher systems. Sulphur in OFP-copper will be found in sulphides. The sulphide can take different morphologies but constant stoichiometry Cu 2 S. The solubility of sulphur in FCC-copper reaches ppm levels already at 550 deg C and decreases with lower temperature. No phosphorus-sulphide will be stable, although the copper sulphide can be replaced by copper sulphates at high partial pressure oxygen like in the oxide scale. Phosphorus has a high affinity to oxygen, and phosphorus oxide P 4 O 10 and copper phosphates (Cu 2 P 2 O 7 and Cu 3 (PO 4 ) 2 ) are all more stable than copper oxide Cu 2 O. With hydrogen present at atmospheric pressure, copper phosphates Cu 2 P 2 O 7 and Cu 3 (P 2 O 6 OH) 2 are both more stable than water vapour or aqueous water at temperatures below 400 deg C. At high pressure conditions, the copper phosphates can be reduced giving water. However, the phosphates are still more stable than water vapour. The solubility limit of phosphorus in FCC-copper at 25 deg C is 510 ppm, in equilibrium with copper phosphide Cu 3 P. The major part of phosphorus in OFP-copper will be in solid solution. Oxygen in FCC-copper has a very low solubility. In the presence of a strong oxide forming element such as phosphorus in OFP-copper, the solubility decreases even more. Copper oxides will become stable first when all phosphorus has been consumed, which takes place at twice the phosphorus content, calculated in weight. Hydrogen has a low solubility in copper, calculated as 0.1 ppm at 675 deg C. No crystalline hydrogen phase has been found stable at atmospheric pressures and above 400 deg C. At lower temperatures the hydrogen containing phosphate Cu 3 (P 2 O 6 OH) 2 can become stable. Measured hydrogen

  10. Phase relations in the Cu-Te-S system at temperatures between 350 and 900 degree C

    DEFF Research Database (Denmark)

    Karup-Møller, Sven

    1994-01-01

    data and optical data on phases A and B are listed. At 350 degree C there exist two liquid fields which at 450 degree C have become one continuous field stretching from Cu45Te55 with low S content to the tellurium corner of the phase diagram and from there to the sulphur corner. With increasing S......, the Cu content of the liquid rapidly decreases to trace amonts. With increasing temperature the field extends into the ternary from the tellurium corner towards the Cu-S join. The boundary of the liquid field in the central portion of the phae diagram towards the sulphur corner does not change position...

  11. Investigation of Polarization Phase Difference Related to Forest Fields Characterizations

    Science.gov (United States)

    Majidi, M.; Maghsoudi, Y.

    2013-09-01

    The information content of Synthetic Aperture Radar (SAR) data significantly included in the radiometric polarization channels, hence polarimetric SAR data should be analyzed in relation with target structure. The importance of the phase difference between two co-polarized scattered signals due to the possible association between the biophysical parameters and the measured Polarization Phase Difference (PPD) statistics of the backscattered signal recorded components has been recognized in geophysical remote sensing. This paper examines two Radarsat-2 images statistics of the phase difference to describe the feasibility of relationship with the physical properties of scattering targets and tries to understand relevance of PPD statistics with various types of forest fields. As well as variation of incidence angle due to affecting on PPD statistics is investigated. The experimental forest pieces that are used in this research are characterized white pine (Pinus strobus L.), red pine (Pinus resinosa Ait.), jack pine (Pinus banksiana Lamb.), white spruce (Picea glauca (Moench Voss), black spruce (Picea mariana (Mill) B.S.P.), poplar (Populus L.), red oak (Quercus rubra L.) , aspen and ground vegetation. The experimental results show that despite of biophysical parameters have a wide diversity, PPD statistics are almost the same. Forest fields distributions as distributed targets have close to zero means regardless of the incidence angle. Also, The PPD distribution are function of both target and sensor parameters, but for more appropriate examination related to PPD statistics the observations should made in the leaf-off season or in bands with lower frequencies.

  12. INVESTIGATION OF POLARIZATION PHASE DIFFERENCE RELATED TO FOREST FIELDS CHARACTERIZATIONS

    Directory of Open Access Journals (Sweden)

    M. Majidi

    2013-09-01

    Full Text Available The information content of Synthetic Aperture Radar (SAR data significantly included in the radiometric polarization channels, hence polarimetric SAR data should be analyzed in relation with target structure. The importance of the phase difference between two co-polarized scattered signals due to the possible association between the biophysical parameters and the measured Polarization Phase Difference (PPD statistics of the backscattered signal recorded components has been recognized in geophysical remote sensing. This paper examines two Radarsat-2 images statistics of the phase difference to describe the feasibility of relationship with the physical properties of scattering targets and tries to understand relevance of PPD statistics with various types of forest fields. As well as variation of incidence angle due to affecting on PPD statistics is investigated. The experimental forest pieces that are used in this research are characterized white pine (Pinus strobus L., red pine (Pinus resinosa Ait., jack pine (Pinus banksiana Lamb., white spruce (Picea glauca (Moench Voss, black spruce (Picea mariana (Mill B.S.P., poplar (Populus L., red oak (Quercus rubra L. , aspen and ground vegetation. The experimental results show that despite of biophysical parameters have a wide diversity, PPD statistics are almost the same. Forest fields distributions as distributed targets have close to zero means regardless of the incidence angle. Also, The PPD distribution are function of both target and sensor parameters, but for more appropriate examination related to PPD statistics the observations should made in the leaf-off season or in bands with lower frequencies.

  13. Two-phase flow in volatile oil reservoir using two-phase pseudo-pressure well test method

    Energy Technology Data Exchange (ETDEWEB)

    Sharifi, M.; Ahmadi, M. [Calgary Univ., AB (Canada)

    2009-09-15

    A study was conducted to better understand the behaviour of volatile oil reservoirs. Retrograde condensation occurs in gas-condensate reservoirs when the flowing bottomhole pressure (BHP) lowers below the dewpoint pressure, thus creating 4 regions in the reservoir with different liquid saturations. Similarly, when the BHP of volatile oil reservoirs falls below the bubblepoint pressure, two phases are created in the region around the wellbore, and a single phase (oil) appears in regions away from the well. In turn, higher gas saturation causes the oil relative permeability to decrease towards the near-wellbore region. Reservoir compositional simulations were used in this study to predict the fluid behaviour below the bubblepoint. The flowing bottomhole pressure was then exported to a well test package to diagnose the occurrence of different mobility regions. The study also investigated the use of a two-phase pseudo-pressure method on volatile and highly volatile oil reservoirs. It was concluded that this method can successfully predict the true permeability and mechanical skin. It can also distinguish between mechanical skin and condensate bank skin. As such, the two-phase pseudo-pressure method is particularly useful for developing after-drilling well treatment and enhanced oil recovery process designs. However, accurate relative permeability and PVT data must be available for reliable interpretation of the well test in volatile oil reservoirs. 18 refs., 3 tabs., 9 figs.

  14. sRNA-Mediated Regulation of P-Fimbriae Phase Variation in Uropathogenic Escherichia coli

    DEFF Research Database (Denmark)

    Khandige, Surabhi; Kronborg, Tina; Uhlin, Bernt Eric

    2015-01-01

    Uropathogenic Escherichia coli (UPEC) are capable of occupying physiologically distinct intracellular and extracellular niches within the urinary tract. This feat requires the timely regulation of gene expression and small RNAs (sRNAs) are known to mediate such rapid adjustments in response to ch...... to changing environmental cues. This study aimed to uncover sRNA-mediated gene regulation in the UPEC strain UTI89, during infection of bladder epithelial cells. Hfq is an RNA chaperone known to facilitate and stabilize sRNA and target mRNA interactions with bacterial cells. The co...... to the discovery of a novel virulence-associated trans-acting sRNA-PapR. Deletion of papR was found to enhance adhesion of UTI89 to both bladder and kidney cell lines in a manner independent of type-1 fimbriae. We demonstrate PapR mediated posttranscriptional repression of the P-fimbriae phase regulator gene pap...

  15. Two-phase flow models in unbounded two-phase critical flows

    International Nuclear Information System (INIS)

    Celata, G.P.; Cumo, M.; Farello, G.E.

    1985-01-01

    With reference to a Loss-of-Coolant Accident in Light Water Reactors, an analysis of the unbounded two-phase critical flow (i.e. the issuing two-phase jet) has been accomplished. Considering jets external shape, obtained by means of photographic pictures; pressure profiles inside the jet, obtained by means of a movable ''Pitot;'' and jet phases distribution information, obtained by means of X-rays pictures; a characterization of the flow pattern in the unbounded region of a two-phase critical flow is given. Jets X-ray pictures show the existence of a central high density ''core'' gradually evaporating all around, which gives place to a characteristic ''dartflow'' the length of which depends on stagnation thermodynamic conditions

  16. Two-phase flow models

    International Nuclear Information System (INIS)

    Delaje, Dzh.

    1984-01-01

    General hypothesis used to simplify the equations, describing two-phase flows, are considered. Two-component and one-component models of two-phase flow, as well as Zuber and Findlay model for actual volumetric steam content, and Wallis model, describing the given phase rates, are presented. The conclusion is made, that the two-component model, in which values averaged in time are included, is applicable for the solving of three-dimensional tasks for unsteady two-phase flow. At the same time, using the two-component model, including values, averaged in space only one-dimensional tasks for unsteady two-phase flow can be solved

  17. Copper Selenidophosphates Cu4P2Se6, Cu4P3Se4, Cu4P4Se3, and CuP2Se, Featuring Zero-, One-, and Two-Dimensional Anions.

    Science.gov (United States)

    Kuhn, Alexander; Schoop, Leslie M; Eger, Roland; Moudrakovski, Igor; Schwarzmüller, Stefan; Duppel, Viola; Kremer, Reinhard K; Oeckler, Oliver; Lotsch, Bettina V

    2016-08-15

    Five new compounds in the Cu/P/Se phase diagram have been synthesized, and their crystal structures have been determined. The crystal structures of these compounds comprise four previously unreported zero-, one-, and two-dimensional selenidophosphate anions containing low-valent phosphorus. In addition to two new modifications of Cu4P2Se6 featuring the well-known hexaselenidohypodiphosphate(IV) ion, there are three copper selenidophosphates with low-valent P: Cu4P3Se4 contains two different new anions, (i) a monomeric (zero-dimensional) selenidophosphate anion [P2Se4](4-) and (ii) a one-dimensional selenidophosphate anion [Formula: see text], which is related to the well-known gray-Se-like [Formula: see text] Zintl anion. Cu4P4Se3 contains one-dimensional [Formula: see text] polyanions, whereas CuP2Se contains the 2D selenidophosphate [Formula: see text] polyanion. It consists of charge-neutral CuP2Se layers separated by a van der Waals gap which is very rare for a Zintl-type phase. Hence, besides black P, CuP2Se constitutes a new possible source of 2D oxidized phosphorus containing layers for intercalation or exfoliation experiments. Additionally, the electronic structures and some fundamental physical properties of the new compounds are reported. All compounds are semiconducting with indirect band gaps of the orders of around 1 eV. The phases reported here add to the structural diversity of chalcogenido phosphates. The structural variety of this family of compounds may translate into a variety of tunable physical properties.

  18. A review of damping of two-phase flows

    International Nuclear Information System (INIS)

    Hara, Fumio

    1993-01-01

    Damping of two-phase flows has been recognized as one of the most unknown parameters in analyzing vibrational characteristics of structures subjected to two-phase flows since it seems to be influenced by many physical parameters involved in the physics of dynamic energy dissipation of a vibrating structure, for example, liquid viscosity, surface tension, flow velocity, mass ratio, frequency, void fraction, flow regime and so forth. This paper deals with a review of scientific works done to date on the damping of two phase flows and discussions about what has been clarified and what has not been known to us, or what kinds of research are needed about two-phase flow damping. The emphasis is put on the definition of two-phase fluid damping, damping measurement techniques, damping characteristics in relation to two phase flow configurations, and damping generation mechanisms

  19. Blocking S1P interaction with S1P{sub 1} receptor by a novel competitive S1P{sub 1}-selective antagonist inhibits angiogenesis

    Energy Technology Data Exchange (ETDEWEB)

    Fujii, Yasuyuki, E-mail: y.fujii@po.rd.taisho.co.jp [Department of Molecular Function and Pharmacology Laboratories, Taisho Pharmaceutical Co. Ltd., 1-403 Saitama, Saitama 331-9530 (Japan); Ueda, Yasuji; Ohtake, Hidenori; Ono, Naoya; Takayama, Tetsuo; Nakazawa, Kiyoshi [Department of Molecular Function and Pharmacology Laboratories, Taisho Pharmaceutical Co. Ltd., 1-403 Saitama, Saitama 331-9530 (Japan); Igarashi, Yasuyuki [Laboratory of Biomembrane and Biofunctional Chemistry, Hokkaido University, Sapporo, Hokkaido 060-0812 (Japan); Goitsuka, Ryo [Division of Development and Aging, Research Institute for Biological Sciences, Tokyo University of Science, Noda, Chiba 278-0022 (Japan)

    2012-03-23

    Highlights: Black-Right-Pointing-Pointer The effect of a newly developed S1P{sub 1}-selective antagonist on angiogenic responses. Black-Right-Pointing-Pointer S1P{sub 1} is a critical component of VEGF-related angiogenic responses. Black-Right-Pointing-Pointer S1P{sub 1}-selective antagonist showed in vitro activity to inhibit angiogenesis. Black-Right-Pointing-Pointer S1P{sub 1}-selective antagonist showed in vivo activity to inhibit angiogenesis. Black-Right-Pointing-Pointer The efficacy of S1P{sub 1}-selective antagonist for anti-cancer therapies. -- Abstract: Sphingosine 1-phosphate receptor type 1 (S1P{sub 1}) was shown to be essential for vascular maturation during embryonic development and it has been demonstrated that substantial crosstalk exists between S1P{sub 1} and other pro-angiogenic growth factors, such as vascular endothelial growth factor (VEGF) and basic fibroblast growth factor. We developed a novel S1P{sub 1}-selective antagonist, TASP0277308, which is structurally unrelated to S1P as well as previously described S1P{sub 1} antagonists. TASP0277308 inhibited S1P- as well as VEGF-induced cellular responses, including migration and proliferation of human umbilical vein endothelial cells. Furthermore, TASP0277308 effectively blocked a VEGF-induced tube formation in vitro and significantly suppressed tumor cell-induced angiogenesis in vivo. These findings revealed that S1P{sub 1} is a critical component of VEGF-related angiogenic responses and also provide evidence for the efficacy of TASP0277308 for anti-cancer therapies.

  20. Parallel two-phase-flow-induced vibrations in fuel pin model

    International Nuclear Information System (INIS)

    Hara, Fumio; Yamashita, Tadashi

    1978-01-01

    This paper reports the experimental results of vibrations of a fuel pin model -herein meaning the essential form of a fuel pin from the standpoint of vibration- in a parallel air-and-water two-phase flow. The essential part of the experimental apparatus consisted of a flat elastic strip made of stainless steel, both ends of which were firmly supported in a circular channel conveying the two-phase fluid. Vibrational strain of the fuel pin model, pressure fluctuation of the two-phase flow and two-phase-flow void signals were measured. Statistical measures such as power spectral density, variance and correlation function were calculated. The authors obtained (1) the relation between variance of vibrational strain and two-phase-flow velocity, (2) the relation between variance of vibrational strain and two-phase-flow pressure fluctuation, (3) frequency characteristics of variance of vibrational strain against the dominant frequency of the two-phase-flow pressure fluctuation, and (4) frequency characteristics of variance of vibrational strain against the dominant frequency of two-phase-flow void signals. The authors conclude that there exist two kinds of excitation mechanisms in vibrations of a fuel pin model inserted in a parallel air-and-water two-phase flow; namely, (1) parametric excitation, which occurs when the fundamental natural frequency of the fuel pin model is related to the dominant travelling frequency of water slugs in the two-phase flow by the ratio 1/2, 1/1, 3/2 and so on; and (2) vibrational resonance, which occurs when the fundamental frequency coincides with the dominant frequency of the two-phase-flow pressure fluctuation. (auth.)

  1. Thermodynamic evaluation of Cu-H-O-S-P system - Phase stabilities and solubilities for OFP-copper

    Energy Technology Data Exchange (ETDEWEB)

    Magnusson, Hans; Frisk, Karin [Swerea KIMAB, Kista (Sweden)

    2013-04-15

    A thermodynamic evaluation for Cu-H-O-S-P has been made, with special focus on the phase stabilities and solubilities for OFP-copper. All binary systems including copper have been reviewed. Gaseous species and stoichiometric crystalline phases have been included for higher systems. Sulphur in OFP-copper will be found in sulphides. The sulphide can take different morphologies but constant stoichiometry Cu{sub 2}S. The solubility of sulphur in FCC-copper reaches ppm levels already at 550 deg C and decreases with lower temperature. No phosphorus-sulphide will be stable, although the copper sulphide can be replaced by copper sulphates at high partial pressure oxygen like in the oxide scale. Phosphorus has a high affinity to oxygen, and phosphorus oxide P{sub 4}O{sub 10} and copper phosphates (Cu{sub 2}P{sub 2}O{sub 7} and Cu{sub 3}(PO{sub 4}){sub 2}) are all more stable than copper oxide Cu{sub 2}O. With hydrogen present at atmospheric pressure, copper phosphates Cu{sub 2}P{sub 2}O{sub 7} and Cu{sub 3}(P{sub 2}O{sub 6}OH){sub 2} are both more stable than water vapour or aqueous water at temperatures below 400 deg C. At high pressure conditions, the copper phosphates can be reduced giving water. However, the phosphates are still more stable than water vapour. The solubility limit of phosphorus in FCC-copper at 25 deg C is 510 ppm, in equilibrium with copper phosphide Cu{sub 3}P. The major part of phosphorus in OFP-copper will be in solid solution. Oxygen in FCC-copper has a very low solubility. In the presence of a strong oxide forming element such as phosphorus in OFP-copper, the solubility decreases even more. Copper oxides will become stable first when all phosphorus has been consumed, which takes place at twice the phosphorus content, calculated in weight. Hydrogen has a low solubility in copper, calculated as 0.1 ppm at 675 deg C. No crystalline hydrogen phase has been found stable at atmospheric pressures and above 400 deg C. At lower temperatures the hydrogen

  2. S-phase Specific Downregulation of Human O6-Methylguanine DNA Methyltransferase (MGMT and its Serendipitous Interactions with PCNA and p21cip1 Proteins in Glioma Cells

    Directory of Open Access Journals (Sweden)

    AGM Mostofa

    2018-04-01

    Full Text Available Whether the antimutagenic DNA repair protein MGMT works solo in human cells and if it has other cellular functions is not known. Here, we show that human MGMT associates with PCNA and in turn, with the cell cycle inhibitor, p21cip1 in glioblastoma and other cancer cell lines. MGMT protein was shown to harbor a nearly perfect PCNA-Interacting Protein (PIP box motif. Isogenic p53-null H1299 cells were engineered to express the p21 protein by two different procedures. Reciprocal immunoprecipitation/western blotting, Far-western blotting, and confocal microscopy confirmed the specific association of MGMT with PCNA and the ability of p21 to strongly disrupt the MGMT-PCNA complexes in tumor cells. Alkylation DNA damage resulted in a greater colocalization of MGMT and PCNA proteins, particularly in HCT116 cells deficient in p21 expression. p21 expression in isogenic cell lines directly correlated with markedly higher levels of MGMT mRNA, protein, activity and greater resistance to alkylating agents. In other experiments, four glioblastoma cell lines synchronized at the G1/S phase using either double thymidine or thymidine-mimosine blocks and subsequent cycling consistently showed a loss of MGMT protein at mid- to late S-phase, irrespective of the cell line, suggesting such a downregulation is fundamental to cell cycle control. MGMT protein was also specifically degraded in extracts from S-phase cells and evidence strongly suggested the involvement of PCNA-dependent CRL4Cdt2 ubiquitin-ligase in the reaction. Overall, these data provide the first evidence for non-repair functions of MGMT in cell cycle and highlight the involvement of PCNA in MGMT downregulation, with p21 attenuating the process.

  3. The geometric phase in two-level atomic systems

    International Nuclear Information System (INIS)

    Tian Mingzhen; Barber, Zeb W.; Fischer, Joe A.; Randall Babbitt, Wm.

    2004-01-01

    We report the observation of the geometric phase in a closed two-level atomic system using stimulated photon echoes. The two-level system studied consists of the two-electronic energy levels ( 3 H 4 and 3 H 6 ) of Tm 3+ doped in YAG crystal. When a two-level atom at an arbitrary superposition state is excited by a pair of specially designed laser pulses, the excited state component gains a relative phase with respect to the ground state component. We identified the phase shift to be of pure geometric nature. The dynamic phase associated to the driving Hamiltonian is unchanged. The experiment results of the phase change agree with the theory to the extent of the measurement limit

  4. Influence and applicability of wire-mesh sensor to acquire two phase flow dynamics

    International Nuclear Information System (INIS)

    Kanai, Taizo; Furuya, Masahiro; Arai, Takahiro; Shirakawa, Kenetsu

    2011-01-01

    Wire-mesh sensors (WMS) are able to measure void distributions and velocity profile at high speed. Immersing the wire-mesh affects the structure of two-phase flow. Experiments were performed for single rising air bubble in a vertical pipe of i.d. 50 mm and 224 mm at water velocities ranging from 0.05 to 0.52 m/s and 0.42 to 0.83 m/s. Distortion of a relatively large bubble with the wire-mesh was small in the water velocity over 0.25 m/s and confirmed by cross-correlation analysis as well. Bubble rising velocity acquired by WMS is in good agreement with that estimated high-speed camera in the experimental range. WMS has applicability to acquire two phase flow dynamics in the water velocity over 0.25 m/s. (author)

  5. Relations between the kinetic equation and the Langevin models in two-phase flow modelling

    International Nuclear Information System (INIS)

    Minier, J.P.; Pozorski, J.

    1997-05-01

    The purpose of this paper is to discuss PDF and stochastic models which are used in two-phase flow modelling. The aim of the present analysis is essentially to try to determine relations and consistency between different models. It is first recalled that different approaches actually correspond to PDF models written either in terms of the process trajectories or in terms of the PDF itself. The main difference lies in the choice of the independent variables which are retained. Two particular models are studied, the Kinetic Equation and the Langevin Equation model. The latter uses a Langevin equation to model the fluid velocities seen along particle trajectories. The Langevin model is more general since it contains an additional variable. It is shown that, in certain cases, this variable can be summed up exactly to retrieve the Kinetic Equation model as a marginal PDF. A joint fluid and solid particle PDF which includes the characteristics of both phases is proposed at the end of the paper. (author)

  6. Tsallis q-triplet and Stock Market Indices: The cases of S & P 500 and TVIX

    Directory of Open Access Journals (Sweden)

    A. C. Iliopoulos

    2015-01-01

    Full Text Available In this study we present results of the evaluation of q − triplet of Tsallis non-extensive statistics concerning two time stock market time series, Standart & Poor’s 500 (S & P 500 and TVIX. The analysis of the results, support the hypothesis in which economic dynamics from physical point of view correspond to far from equilibrium spatial distributed non-linear dynamics. In particular, the analysis of the stock market time series revealed underlying complex dynamics, indicating clearly that the statistics of the dynamics in the multifractal phase space can be described by Tsallis distribution functions of power law and heavy tails forms. The non-extensive character of the underlying dynamics is related to the existence of long range interactions in space and time, as well as the interaction in many scales. In addition, the detailed analysis of S & P index unraveled the existence of non-equilibrium phase transitions depicted clearly in the variations of Tsallis q-triplet values. These phase transitions are connected with non-equilibrium stationary states of economical dynamics derived from processes of strong self organization which correspond to local maxima of Tsallis entropy, while the changes in the control parameters can induce new phase transitions and shifts to new metaequilibrium steady states of maximizing Tsallis entropy. These phase transitions lead to changes in Tsallis qtriplet values which correspond to multi-fractal changes in the formation of the phase state and an alteration in the phenomenology of the economical system. Finally, these characteristics also indicate the existence of fractional dynamics in the phase space which can be described through fractional Fokker-Planck equations and anomalous diffusion equations. The solutions of these equations are fractional spatiotemporal functions and non-Gaussian distributions functions which fall into the category of Levy distributions and Tsallis distributions.

  7. Selective UV radiation detection on the basis of low-dimensional ZnCdS/ZnMgS/GaP and ZnCdS/ZnS/GaP heterostructures

    Energy Technology Data Exchange (ETDEWEB)

    Averin, S. V., E-mail: sva278@ire216.msk.su; Kuznetzov, P. I.; Zhitov, V. A.; Zakharov, L. Yu.; Kotov, V. M.; Alkeev, N. V. [Russian Academy of Sciences, Fryazino Branch, Kotel’nikov Institute of Radio Engineering and Electronics (Russian Federation); Gladisheva, N. B. [Pulsar State Plant (Russian Federation)

    2015-11-15

    The detecting properties of periodic heterostructures with ZnCdS quantum wells separated by ZnMgS or ZnS barrier layers are studied. Heterostructures are grown on semi-insulating GaP substrates by metal organic vapor-phase epitaxy (MOVPE). On their basis, metal–semiconductor–metal (MSM) diodes with interdigital Schottky contacts 3 μm, distances between them of 3 μm, and a total detector area of 100 × 100 μm are fabricated. The detectors have low dark currents (10{sup –12} A); at low bias voltages, they provide a narrow- band response (full-width at half-maximum of FWHM = 18 nm at a wavelength of 350 nm) which is controlled by the ZnCdS quantum-well composition. As bias is increased to 70 V, the maximum detector sensitivity shifts by a wavelength of 450 nm, which is caused by penetration of the external-bias electric field into the semi-insulating GaP substrate. In this case, the narrow-band response of the detector at a wavelength of 350 nm is retained, i.e., the two-color detection of light is provided.

  8. State of the art: two-phase flow calibration techniques

    International Nuclear Information System (INIS)

    Stanley, M.L.

    1977-01-01

    The nuclear community faces a particularly difficult problem relating to the calibration of instrumentation in a two-phase flow steam/water environment. The rationale of the approach to water reactor safety questions in the United States demands that accurate measurements of mass flows in a decompressing two-phase flow be made. An accurate measurement dictates an accurate calibration. This paper addresses three questions relating to the state of the art in two-phase calibration: (1) What do we mean by calibration. (2) What is done now. (3) What should be done

  9. Theory for disordered phase in Heisenberg and non-Heisenberg two-dimensional S=1 ferromagnets

    International Nuclear Information System (INIS)

    Spirin, D.V.; Fridman, Yu.A.

    2003-01-01

    We apply a modification of self-consistent spin-wave theory to investigation of two-dimensional S=1 isotropic Heisenberg and non-Heisenberg ferromagnets at nonzero temperatures. We use Hubbard operators method and bosonization technique. We calculated chemical potential and found dependence of correlation length on temperature. Specific heat has Schottky-type peak and decreases at high temperatures. Disordered phase in non-Heisenberg ferromagnet is also studied. The results for such a model differ from those of Heisenberg one

  10. Clapeyron equation and phase equilibrium properties in higher dimensional charged topological dilaton AdS black holes with a nonlinear source

    Energy Technology Data Exchange (ETDEWEB)

    Li, Huai-Fan; Zhao, Hui-Hua; Zhang, Li-Chun; Zhao, Ren [Shanxi Datong University, Institute of Theoretical Physics, Datong (China); Shanxi Datong University, Department of Physics, Datong (China)

    2017-05-15

    Using Maxwell's equal area law, we discuss the phase transition of higher dimensional charged topological dilaton AdS black hole with a nonlinear source. The coexisting region of the two phases is found and we depict the coexistence region in the P-v diagrams. The two-phase equilibrium curves in the P-T diagrams are plotted, and we take the first order approximation of volume v in the calculation. To better compare with a general thermodynamic system, the Clapeyron equation is derived for a higher dimensional charged topological black hole with a nonlinear source. The latent heat of an isothermal phase transition is investigated. We also study the effect of the parameters of the black hole on the region of two-phase coexistence. The results show that the black hole may go through a small-large phase transition similar to those of usual non-gravity thermodynamic systems. (orig.)

  11. Two Phase Flow Simulation Using Cellular Automata

    International Nuclear Information System (INIS)

    Marcel, C.P.

    2002-01-01

    The classical mathematical treatment of two-phase flows is based on the average of the conservation equations for each phase.In this work, a complementary approach to the modeling of these systems based on statistical population balances of aut omata sets is presented.Automata are entities defined by mathematical states that change following iterative rules representing interactions with the neighborhood.A model of automata for two-phase flow simulation is presented.This model consists of fie lds of virtual spheres that change their volumes and move around a certain environment.The model is more general than the classical cellular automata in two respects: the grid of cellular automata is dismissed in favor of a trajectory generator, and the rules of interaction involve parameters representing the actual physical interactions between phases.Automata simulation was used to study unsolved two-phase flow problems involving high heat flux rates. One system described in this work consists of a vertical channel with saturated water at normal pressure heated from the lower surface.The heater causes water to boil and starts the bubble production.We used cellular automata to describe two-phase flows and the interaction with the heater.General rule s for such cellular automata representing bubbles moving in stagnant liquid were used, with special attention to correct modeling of different mechanisms of heat transfer.The results of the model were compared to previous experiments and correlations finding good agreement.One of the most important findings is the confirmation of Kutateladze's idea about a close relation between the start of critical heat flux and a change in the flow's topology.This was analyzed using a control volume located in the upper surface of the heater.A strong decrease in the interfacial surface just before the CHF start was encountered.The automata describe quite well some characteristic parameters such as the shape of the local void fraction in the

  12. Magnetic liquid metal two-phase flow research. Phase 1. Final report

    International Nuclear Information System (INIS)

    Graves, R.D.

    1983-04-01

    The Phase I research demonstrates the feasibility of the magnetic liquid metal (MLM) two-phase flow concept. A dispersion analysis is presented based on a complete set of two-phase-flow equations augmented to include stresses due to magnetic polarization of the fluid. The analysis shows that the stability of the MLM two-phase flow is determined by the magnetic Mach number, the slip ratio, geometry of the flow relative to the applied magnetic field, and by the voidage dependence of the interfacial forces. Results of a set of experiments concerned with magnetic effects on the dynamics of single bubble motion in an aqueous-based, viscous, conducting magnetic fluid are presented. Predictions in the theoretical literature are qualitatively verified using a bench-top experimental apparatus. In particular, applied magnetic fields are seen to lead to reduced bubble size at fixed generating orifice pressure

  13. Application of non-equilibrium thermodynamics to two-phase flows with a change of phase

    International Nuclear Information System (INIS)

    Delhaye, J.M.

    1969-01-01

    In this report we use the methods of non-equilibrium thermodynamics in two-phase flows. This paper follows a prior one in which we have studied the conservation laws and derived the general equations of two-phase flow. In the first part the basic ideas of thermodynamics of irreversible systems are given. We follow the classical point of view. The second part is concerned with the derivation of a closed set of equations for the two phase elementary volume model. In this model we assume that the elementary volume contains two phases and that it is possible to define a volumetric local concentration. To obtain the entropy balance we can choose either the reversibility of the barycentric motion or the reversibility of each phase. We adopt the last assumption and our derivation is the same as this of I.Prigogine and P. Mazur about the hydrodynamics of liquid helium. The scope of this work is not to find a general solution to the problems of two phase flows but to obtain a new set of equations which may be used to explain some characteristic phenomena of two-phase flow such as wave propagation or critical states. (author) [fr

  14. Simulation of the phenomenon of single-phase and two-phase natural circulation

    International Nuclear Information System (INIS)

    Castrillo, Lazara Silveira

    1998-02-01

    Natural convection phenomenon is often used to remove the residual heat from the surfaces of bodies where the heat is generated e.g. during accidents or transients of nuclear power plants. Experimental study of natural circulation can be done in small scale experimental circuits and the results can be extrapolated for larger operational facilities. The numerical analysis of transients can be carried out by using large computational codes that simulate the thermohydraulic behavior in such facilities. The computational code RELAP5/MOD2, (Reactor Excursion and Leak Analysis Program) was developed by U.S. Nuclear Regulatory Commissions's. Division of Reactor Safety Research with the objective of analysis of transients and postulated accidents in the light water reactor (LWR) systems, including small and large ruptures with loss of coolant accidents (LOCA's). The results obtained by the simulation of single-phase and two-phase natural circulation, using the RELAP5/MOD2, are presented in this work. The study was carried out using the experimental circuit built at the 'Departamento de Engenharia Quimica da Escola Politecnica da Universidade de Sao Paulo'. In the circuit, two experiments were carried out with different conditions of power and mass flow, obtaining a single-phase regime with a level of power of 4706 W and flow of 5.10 -5 m 3 /s (3 l/min) and a two-phase regime with a level of power of 6536 W and secondary flow 2,33.10 -5 m 3 /s (1,4 l/min). The study allowed tio evaluate the capacity of the code for representing such phenomena as well as comparing the transients obtained theoretically with the experimental results. The comparative analysis shows that the code represents fairly well the single-phase transient, but the results for two-phase transients, starting from the nodalization and calibration used for the case single-phase transient, did not reproduce faithfully some experimental results. (author)

  15. Nuclear AP4A-binding activity of sea urchin embryos changes in relation to the initiation of S phase

    International Nuclear Information System (INIS)

    Morioka, M.; Shimada, H.

    1986-01-01

    The AP 4 A-binding activity of sea urchin embryos was studied using radioactively labelled diadenosine 5', 5'''-P 1 ,P 4 -tetraphosphate (Ap 4 A). Among various subcellular components that can bind [ 3 H]AP 4 A, nuclei alone showed the highly specific Ap 4 A-binding activity which was not influenced by the presence of AP 4 A, AP 5 A and GP 4 G. The addition of an excess amount of ATP only slightly reduced the binding of [ 3 H]AP 4 A to the nuclei. It was found that AP 4 A binds to the residual proteinaceous structure of nuclei which was resistant to the extraction with 2 M NaCl. The nuclear AP 4 A-binding activity fluctuated cyclically during each cell cycle, with at transient increase at the beginning of S phase followed by an abrupt-decrease within 10 min. When the initiation of S phase was blocked, the increase in the AP 4 A-binding activity was also prevented. It seems that the binding of AP 4 A to the nuclear structural protein is involved in the initiation of S phase

  16. Two-body Dirac equations for nucleon-nucleon scattering

    International Nuclear Information System (INIS)

    Liu Bin; Crater, Horace

    2003-01-01

    We investigate the nucleon-nucleon interaction by using the meson exchange model and the two-body Dirac equations of constraint dynamics. This approach to the two-body problem has been successfully tested for QED and QCD relativistic bound states. An important question we wish to address is whether or not the two-body nucleon-nucleon scattering problem can be reasonably described in this approach as well. This test involves a number of related problems. First we must reduce our two-body Dirac equations exactly to a Schroedinger-like equation in such a way that allows us to use techniques to solve them already developed for Schroedinger-like systems in nonrelativistic quantum mechanics. Related to this, we present a new derivation of Calogero's variable phase shift differential equation for coupled Schroedinger-like equations. Then we determine if the use of nine meson exchanges in our equations gives a reasonable fit to the experimental scattering phase shifts for n-p scattering. The data involve seven angular momentum states including the singlet states 1 S 0 , 1 P 1 , 1 D 2 and the triplet states 3 P 0 , 3 P 1 , 3 S 1 , 3 D 1 . Two models that we have tested give us a fairly good fit. The parameters obtained by fitting the n-p experimental scattering phase shift give a fairly good prediction for most of the p-p experimental scattering phase shifts examined (for the singlet states 1 S 0 , 1 D 2 and triplet states 3 P 0 , 3 P 1 ). Thus the two-body Dirac equations of constraint dynamics present us with a fit that encourages the exploration of a more realistic model. We outline generalizations of the meson exchange model for invariant potentials that may possibly improve the fit

  17. Experimental study on local resistance of two-phase flow through spacer grid with rod bundle

    International Nuclear Information System (INIS)

    Yan Chaoxing; Yan Changqi; Sun Licheng; Tian Qiwei

    2015-01-01

    The experimental study on local resistance of single-phase and two-phase flows through a spacer grid in a vertical channel with 3 × 3 rod bundle was carried out under the normal temperature and pressure. For the case of single-phase flow, the liquid Reynolds number covered the range of 290-18 007. For the case of two-phase flow, the ranges of gas and liquid superficial velocities were 0.013-3.763 m/s and 0.076-1.792 m/s, respectively. A correlation for predicting local resistance of single-phase flow was given based on experimental results. Eight classical two-phase viscosity formulae for homogeneous model were evaluated against the experimental data of two-phase flow. The results show that Dukler model predicts the experimental data well in the range of Re 1 < 9000 while McAdams correlation is the best one for Re 1 ≥ 9000. For all experimental data, Dukler model provides the best prediction with the mean relative error of 29.03%. A new correlation is fitted for the range of Re 1 < 9000 by considering mass quality, two- phase Reynolds number and liquid and gas densities, resulting in a good agreement with the experimental data. (authors)

  18. Possible effects of two-phase flow pattern on the mechanical behavior of mudstones

    Science.gov (United States)

    Goto, H.; Tokunaga, T.; Aichi, M.

    2016-12-01

    To investigate the influence of two-phase flow pattern on the mechanical behavior of mudstones, laboratory experiments were conducted. In the experiment, air was injected from the bottom of the water-saturated Quaternary Umegase mudstone sample under hydrostatic external stress condition. Both axial and circumferential strains at half the height of the sample and volumetric discharge of water at the outlet were monitored during the experiment. Numerical simulation of the experiment was tried by using a simulator which can solve coupled two-phase flow and poroelastic deformation assuming the extended-Darcian flow with relative permeability and capillary pressure as functions of the wetting-phase fluid saturation. In the numerical simulation, the volumetric discharge of water was reproduced well while both strains were not. Three dimensionless numbers, i.e., the viscosity ratio, the Capillary number, and the Bond number, which characterize the two-phase flow pattern (Lenormand et al., 1988; Ewing and Berkowitz, 1998) were calculated to be 2×10-2, 2×10-11, and 7×10-11, respectively, in the experiment. Because the Bond number was quite small, it was possible to apply Lenormand et al. (1988)'s diagram to evaluate the flow regime, and the flow regime was considered to be capillary fingering. While, in the numerical simulation, air moved uniformly upward with quite low non-wetting phase saturation conditions because the fluid flow obeyed the two-phase Darcy's law. These different displacement patterns developed in the experiment and assumed in the numerical simulation were considered to be the reason why the deformation behavior observed in the experiment could not be reproduced by numerical simulation, suggesting that the two-phase flow pattern could affect the changes of internal fluid pressure patterns during displacement processes. For further studies, quantitative analysis of the experimental results by using a numerical simulator which can solve the coupled

  19. Non-Darcy behavior of two-phase channel flow.

    Science.gov (United States)

    Xu, Xianmin; Wang, Xiaoping

    2014-08-01

    We study the macroscopic behavior of two-phase flow in porous media from a phase-field model. A dissipation law is first derived from the phase-field model by homogenization. For simple channel geometry in pore scale, the scaling relation of the averaged dissipation rate with the velocity of the two-phase flow can be explicitly obtained from the model which then gives the force-velocity relation. It is shown that, for the homogeneous channel surface, Dacry's law is still valid with a significantly modified permeability including the contribution from the contact line slip. For the chemically patterned surfaces, the dissipation rate has a non-Darcy linear scaling with the velocity, which is related to a depinning force for the patterned surface. Our result offers a theoretical understanding on the prior observation of non-Darcy behavior for the multiphase flow in either simulations or experiments.

  20. A double parameters measurement of steam-water two-phase flow with single orifice

    International Nuclear Information System (INIS)

    Zhong Shuoping; Tong Yunxian; Yu Meiying

    1992-08-01

    A double parameters measurement of steam-water two-phase flow with single orifice is described. An on-line measurement device based on micro-computer has been developed. The measured r.m.s error of steam quality is less than 6.5% and the measured relative r.m.s. error of mass flow rate is less than 9%

  1. Review of two-phase instabilities

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Han Ok; Seo, Han Ok; Kang, Hyung Suk; Cho, Bong Hyun; Lee, Doo Jeong

    1997-06-01

    KAERI is carrying out a development of the design for a new type of integral reactors. The once-through helical steam generator is important design features. The study on designs and operating conditions which prevent flow instability should precede the introduction of one-through steam generator. Experiments are currently scheduled to understand two-phase instability, evaluate the effect of each design parameter on the critical point, and determine proper inlet throttling for the prevention of instability. This report covers general two-phase instability with review of existing studies on this topics. The general classification of two phase flow instability and the characteristics of each type of instability are first described. Special attention is paid to BWR core flow instability and once-through steam generator instability. The reactivity feedback and the effect of system parameters are treated mainly for BWR. With relation to once-through steam generators, the characteristics of convective heating and dryout point oscillation are first investigated and then the existing experimental studies are summarized. Finally chapter summarized the proposed correlations for instability boundary conditions. (author). 231 refs., 5 tabs., 47 figs

  2. Melting phase relations in the Fe-S and Fe-S-O systems at core conditions in small terrestrial bodies

    Science.gov (United States)

    Pommier, Anne; Laurenz, Vera; Davies, Christopher J.; Frost, Daniel J.

    2018-05-01

    We report an experimental investigation of phase equilibria in the Fe-S and Fe-S-O systems. Experiments were performed at high temperatures (1400-1850 °C) and high pressures (14 and 20 GPa) using a multi-anvil apparatus. The results of this study are used to understand the effect of sulfur and oxygen on core dynamics in small terrestrial bodies. We observe that the formation of solid FeO grains occurs at the Fe-S liquid - Fe solid interface at high temperature ( > 1400 °C at 20 GPa). Oxygen fugacities calculated for each O-bearing sample show that redox conditions vary from ΔIW = -0.65 to 0. Considering the relative density of each phase and existing evolutionary models of terrestrial cores, we apply our experimental results to the cores of Mars and Ganymede. We suggest that the presence of FeO in small terrestrial bodies tends to contribute to outer-core compositional stratification. Depending on the redox and thermal history of the planet, FeO may also help form a transitional redox zone at the core-mantle boundary.

  3. A TWO-PHASE SCENARIO FOR BULGE ASSEMBLY IN {Lambda}CDM COSMOLOGIES

    Energy Technology Data Exchange (ETDEWEB)

    Obreja, A.; Dominguez-Tenreiro, R.; Brook, C. [Departamento de Fisica Teorica, Universidad Autonoma de Madrid, E-28049 Cantoblanco Madrid (Spain); Martinez-Serrano, F. J.; Domenech-Moral, M.; Serna, A. [Departamento de Fisica y Arquitectura de Computadores, Universidad Miguel Hernandez, E-03202 Elche (Spain); Molla, M. [Departamento de Investigacion Basica, CIEMAT, E-28040 Madrid (Spain); Stinson, G., E-mail: aura.obreja@uam.es [Max-Planck-Institut fuer Astronomie, Koenigstuhl 17, D-69117, Heidelberg (Germany)

    2013-01-20

    We analyze and compare the bulges of a sample of L {sub *} spiral galaxies in hydrodynamical simulations in a cosmological context, using two different codes, P-DEVA and GASOLINE. The codes regulate star formation in very different ways, with P-DEVA simulations inputting low star formation efficiency under the assumption that feedback occurs on subgrid scales, while the GASOLINE simulations have feedback that drives large-scale outflows. In all cases, the marked knee shape in mass aggregation tracks, corresponding to the transition from an early phase of rapid mass assembly to a later slower one, separates the properties of two populations within the simulated bulges. The bulges analyzed show an important early starburst resulting from the collapse-like fast phase of mass assembly, followed by a second phase with lower star formation, driven by a variety of processes such as disk instabilities and/or mergers. Classifying bulge stellar particles identified at z = 0 into old and young according to these two phases, we found bulge stellar sub-populations with distinct kinematics, shapes, stellar ages, and metal contents. The young components are more oblate, generally smaller, more rotationally supported, with higher metallicity and less alpha-element enhanced than the old ones. These results are consistent with the current observational status of bulges, and provide an explanation for some apparently paradoxical observations, such as bulge rejuvenation and metal-content gradients observed. Our results suggest that bulges of L {sub *} galaxies will generically have two bulge populations that can be likened to classical and pseudo-bulges, with differences being in the relative proportions of the two, which may vary due to galaxy mass and specific mass accretion and merger histories.

  4. Multiphysics modeling of two-phase film boiling within porous corrosion deposits

    Energy Technology Data Exchange (ETDEWEB)

    Jin, Miaomiao, E-mail: mmjin@mit.edu; Short, Michael, E-mail: hereiam@mit.edu

    2016-07-01

    Porous corrosion deposits on nuclear fuel cladding, known as CRUD, can cause multiple operational problems in light water reactors (LWRs). CRUD can cause accelerated corrosion of the fuel cladding, increase radiation fields and hence greater exposure risk to plant workers once activated, and induce a downward axial power shift causing an imbalance in core power distribution. In order to facilitate a better understanding of CRUD's effects, such as localized high cladding surface temperatures related to accelerated corrosion rates, we describe an improved, fully-coupled, multiphysics model to simulate heat transfer, chemical reactions and transport, and two-phase fluid flow within these deposits. Our new model features a reformed assumption of 2D, two-phase film boiling within the CRUD, correcting earlier models' assumptions of single-phase coolant flow with wick boiling under high heat fluxes. This model helps to better explain observed experimental values of the effective CRUD thermal conductivity. Finally, we propose a more complete set of boiling regimes, or a more detailed mechanism, to explain recent CRUD deposition experiments by suggesting the new concept of double dryout specifically in thick porous media with boiling chimneys. - Highlights: • A two-phase model of CRUD's effects on fuel cladding is developed and improved. • This model eliminates the formerly erroneous assumption of wick boiling. • Higher fuel cladding temperatures are predicted when accounting for two-phase flow. • Double-peaks in thermal conductivity vs. heat flux in experiments are explained. • A “double dryout” mechanism in CRUD is proposed based on the model and experiments.

  5. Aerodynamic Performance of a NREL S809 Airfoil in an Air-Sand Particle Two-Phase Flow

    Directory of Open Access Journals (Sweden)

    Dimitra C. Douvi

    2017-02-01

    Full Text Available This paper opens up a new perspective on the aerodynamic performance of a wind turbine airfoil. More specifically, the paper deals with a steady, incompressible two-phase flow, consisting of air and two different concentrations of sand particles, over an airfoil from the National Renewable Energy Laboratory, NREL S809. The numerical simulations were performed on turbulence models for aerodynamic operations using commercial computational fluid dynamics (CFD code. The computational results obtained for the aerodynamic performance of an S809 airfoil at various angles of attack operating at Reynolds numbers of Re = 1 × 106 and Re = 2 × 106 in a dry, dusty environment were compared with existing experimental data on air flow over an S809 airfoil from reliable sources. Notably, a structured mesh consisting of 80,000 cells had already been identified as the most appropriate for numerical simulations. Finally, it was concluded that sand concentration significantly affected the aerodynamic performance of the airfoil; there was an increase in the values of the predicted drag coefficients, as well as a decrease in the values of the predicted lift coefficients caused by increasing concentrations of sand particles. The region around the airfoil was studied by using contours of static pressure and discrete phase model (DPM concentration.

  6. Nonlinear dynamics of two-phase flow

    International Nuclear Information System (INIS)

    Rizwan-uddin

    1986-01-01

    Unstable flow conditions can occur in a wide variety of laboratory and industry equipment that involve two-phase flow. Instabilities in industrial equipment, which include boiling water reactor (BWR) cores, steam generators, heated channels, cryogenic fluid heaters, heat exchangers, etc., are related to their nonlinear dynamics. These instabilities can be of static (Ledinegg instability) or dynamic (density wave oscillations) type. Determination of regions in parameters space where these instabilities can occur and knowledge of system dynamics in or near these regions is essential for the safe operation of such equipment. Many two-phase flow engineering components can be modeled as heated channels. The set of partial differential equations that describes the dynamics of single- and two-phase flow, for the special case of uniform heat flux along the length of the channel, can be reduced to a set of two coupled ordinary differential equations [in inlet velocity v/sub i/(t) and two-phase residence time tau(t)] involving history integrals: a nonlinear ordinary functional differential equation and an integral equation. Hence, to solve these equations, the dependent variables must be specified for -(nu + tau) ≤ t ≤ 0, where nu is the single-phase residence time. This system of nonlinear equations has been solved analytically using asymptotic expansion series for finite but small perturbations and numerically using finite difference techniques

  7. Two phase sampling

    CERN Document Server

    Ahmad, Zahoor; Hanif, Muhammad

    2013-01-01

    The development of estimators of population parameters based on two-phase sampling schemes has seen a dramatic increase in the past decade. Various authors have developed estimators of population using either one or two auxiliary variables. The present volume is a comprehensive collection of estimators available in single and two phase sampling. The book covers estimators which utilize information on single, two and multiple auxiliary variables of both quantitative and qualitative nature. Th...

  8. Quantum-Classical Phase Transition of the Escape Rate of Two-Sublattice Antiferromagnetic Large Spins

    Science.gov (United States)

    Owerre, Solomon Akaraka; Paranjape, M. B.

    2014-11-01

    The Hamiltonian of a two-sublattice antiferromagnetic spins, with single (hard-axis) and double ion anisotropies described by H = J {\\hat S}1...\\hatS 2-2Jz \\hat {S}1z\\hat {S}2z+K(\\hat {S}1z2 +\\hat {S}2z2) is investigated using the method of effective potential. The problem is mapped to a single particle quantum-mechanical Hamiltonian in terms of the relative coordinate and reduced mass. We study the quantum-classical phase transition of the escape rate of this model. We show that the first-order phase transition for this model sets in at the critical value Jc = (Kc+Jz, c)/2 while for the anisotropic Heisenberg coupling H = J(S1xS2x +S1yS2y) + JzS1zS2z + K(S1z2+ S2z2) we obtain Jc = (2Kc-Jz, c)/3. The phase diagrams of the transition are also studied.

  9. The effect of pore-scale geometry and wettability on two-phase relative permeabilities within elementary cells

    Science.gov (United States)

    Bianchi Janetti, Emanuela; Riva, Monica; Guadagnini, Alberto

    2017-04-01

    We study the relative role of the complex pore space geometry and wettability of the solid matrix on the quantification of relative permeabilities characterizing steady state immiscible two-phase flow in porous media. We do so by considering elementary cells, which are typically employed in upscaling frameworks based on, e.g., homogenization or volume averaging. In this context one typically relies on the solution of pore-scale physics at a scale which is much smaller than that of an investigated porous system. Pressure-driven two-phase flow following simultaneous co-current injection of water and oil is numerically solved for a suite of regular and stochastically generated two-dimensional explicit elementary cells with fixed porosity and sharing main topological/morphological features. We show that relative permeabilities of the randomly generated elementary cells are significantly influenced by the formation of preferential percolation paths (principal pathways), giving rise to a strongly nonuniform distribution of fluid fluxes. These pathways are a result of the spatially variable resistance that the random pore structures exert on the fluid. The overall effect on relative permeabilities of the diverse organization of principal pathways, as driven by a given random realization at the scale of the unit cell, is significantly larger than that of the wettability of the host rock. In contrast to what can be observed for the random cells analyzed, relative permeabilities of regular cells display a clear trend with contact angle at the investigated scale. Our findings suggest the need to perform systematic upscaling studies in a stochastic context, to propagate the effects of uncertain pore space geometries to a probabilistic description of relative permeability curves at the continuum scale.

  10. Pressure-induced phase transition in KxFe2-yS2

    International Nuclear Information System (INIS)

    Tsuchiya, Yuu; Ikeda, Shugo; Kobayashi, Hisao; Zhang, Xiao-Wei; Kishimoto, Shunji; Kikegawa, Takumi; Hirao, Naohisa; Kawaguchi, Saori I.; Ohishi, Yasuo

    2017-01-01

    The structural and electronic properties of high-quality K 0.66(6) Fe 1.75(10) S 2 single crystals have been investigated by angle-resolved X-ray diffraction and 57 Fe nuclear forward scattering using synchrotron radiation under pressure at room temperature. The samples exhibit phase separation into antiferromagnetic ordered K 2 Fe 4 S 5 and nonmagnetic K x Fe 2 S 2 phases. It was found that a pressure-induced phase transition occurs at p c = 5.9(4) GPa with simultaneous suppression of the antiferromagnetic and Fe vacancy orders. >From the results of 57 Fe nuclear forward scattering, the refined magnetic hyperfine field remains unchanged with pressure below p c , suggesting that the Néel temperature does not decrease with pressure up to p c . Above p c , all Fe atoms in K 0.66 Fe 1.75 S 2 are in the same nonmagnetic state. A discontinuous increase in the center shift was observed at p c , reflecting a change in the Fe electronic state in K 0.66 Fe 1.75 S 2 . (author)

  11. Pressure induced phase transition in Pb6Bi2S9

    DEFF Research Database (Denmark)

    Olsen, Lars Arnskov; Friese, Karen; Makovicky, Emil

    2011-01-01

    consists of two types of moduli with SnS/TlI archetype structure in which the Pb and Bi lone pairs are strongly expressed. The mechanism of the phase transition is described in detail and the results are compared to the closely related phase transition in Pb3Bi2S6 (lillianite).......The crystal structure of Pb6Bi2S9 is investigated at pressures between 0 and 5.6 GPa with X-ray diffraction on single-crystals. The pressure is applied using diamond anvil cells. Heyrovskyite (Bbmm, a = 13.719(4) Å, b = 31.393(9) Å, c = 4.1319(10) Å, Z = 4) is the stable phase of Pb6Bi2S9...... at ambient conditions and is built from distorted moduli of PbS-archetype structure with a low stereochemical activity of the Pb2+ and Bi3+ lone electron pairs. Heyrovskyite is stable until at least 3.9 GPa and a first-order phase transition occurs between 3.9 and 4.8 GPa. A single-crystal is retained after...

  12. Structure of some relative relation modules of finite p-groups

    International Nuclear Information System (INIS)

    Yamin, M.

    1990-06-01

    Let G be a finite p-group generated by (g i , 1 ≤ i ≤ d), G i the cyclic subgroup generated by g i , E the free product of the G i , 1 ≤ i ≤ d, and S the kernel of the natural epimorphism of E onto G. The largest elementary abelian p-quotient S-circumflex = S/S'S p , regarded as an IF p G-module via conjugation in E, is called a relative relation module of G. If d is the minimum number of generaters for G, the author has proved that S-circumflex is nonprojective and indecomposable. The aim of this paper is to give an alternative proof for the indecomposability of S-circumflex; the proof here is more informative as it deals with Loewy structure and generating sets of S-circumflex and other associated modules. (author). 9 refs

  13. Two-phase flow in fractured rock

    International Nuclear Information System (INIS)

    Davies, P.; Long, J.; Zuidema, P.

    1993-11-01

    This report gives the results of a three-day workshop on two-phase flow in fractured rock. The workshop focused on two-phase flow processes that are important in geologic disposal of nuclear waste as experienced in a variety of repository settings. The goals and objectives of the workshop were threefold: exchange information; describe the current state of understanding; and identify research needs. The participants were divided into four subgroups. Each group was asked to address a series of two-phase flow processes. The following groups were defined to address these processes: basic flow processes; fracture/matrix interactions; complex flow processes; and coupled processes. For each process, the groups were asked to address these four issues: (1) describe the two-phase flow processes that are important with respect to repository performance; (2) describe how this process relates to the specific driving programmatic issues given above for nuclear waste storage; (3) evaluate the state of understanding for these processes; and (4) suggest additional research to address poorly understood processes relevant to repository performance. The reports from each of the four working groups are given here

  14. Structural phase transitions in BaMo6S8: Evidence for an incommensurate phase

    International Nuclear Information System (INIS)

    Jorgensen, J.D.; Hinks, D.G.; Hatch, D.M.; Putnam, R.M.

    1986-01-01

    The structure of BaMo 6 S 8 has been studied over the temperature range 19 K to 573 K by time-of-flight neutron powder diffraction. Below 175 K the data can be suitably refined in a triclinic, P1, cell with volume equal to the rhombohedral, R3, cell common to most Chevrel-phase structures. At temperatures immediately above 175 K, the rhombohedral, R3, Bragg peaks are broadened by satellite reflections which appear to be identical to those recently observed at low temperature in PbMo 6 S 8 and SnMo 6 S 8 . An abrupt change in the sign of the temperature dependence of the hexagonal c axis (∂c/∂T) signals the transition to an undistorted rhombohedral, R3, structure at temperatures above about 350 K. An extended Landau theory determines both continuous and discontinuous transitions from R3 induced by a single order parameter. Analysis of the order parameters inducing commensurate transitions imposes symmetry restrictions on the atomic displacements in the lower symmetry phases. The assumption of an R3 commensurate phase is not consistent with the bond lengths obtained for the distortions to the P1 (or P1) phase for any of the possible cells preserving order parameters. Thus the phase immediately above 175 K cannot be a commensurate R3 structure. This is consistent with experimental evidence. 25 refs., 11 figs., 8 tabs

  15. CFD Simulations of Pb-Bi Two-Phase Flow

    International Nuclear Information System (INIS)

    Dostal, Vaclav; Zelezny, Vaclav; Zacha, Pavel

    2008-01-01

    In a Pb-Bi cooled direct contact steam generation fast reactor water is injected directly above the core, the produced steam is separated at the top and is send to the turbine. Neither the direct contact phenomenon nor the two-phase flow simulations in CFD have been thoroughly described yet. A first attempt in simulating such two-phase flow in 2D using the CFD code Fluent is presented in this paper. The volume of fluid explicit model was used. Other important simulation parameters were: pressure velocity relation PISO, discretization scheme body force weighted for pressure, second order upwind for momentum and CISCAM for void fraction. Boundary conditions were mass flow inlet (Pb-Bi 0 kg/s and steam 0.07 kg/s) and pressure outlet. The effect of mesh size (0.5 mm and 0.2 mm cells) was investigated as well as the effect of the turbulent model. It was found that using a fine mesh is very important in order to achieve larger bubbles and the turbulent model (k-ε realizable) is necessary to properly model the slug flow. The fine mesh and unsteady conditions resulted in computationally intense problem. This may pose difficulties in 3D simulations of the real experiments. (authors)

  16. Fluid-elastic vibration in two-phase cross flow

    International Nuclear Information System (INIS)

    Sasakawa, T.; Serizawa, A.; Kawara, Z.

    2003-01-01

    The present work aims at clarifying the mechanisms of fluid elastic vibration of tube bundles in two-phase cross flow. The experiment is conducted using air-water two-phase flow under atmospheric pressure. The test section is a 1.03m long transparent acrylic square duct with 128 x 128 mm 2 cross section, which consists of 3 rod-rows with 5 rods in each row. The rods are 125mm long aluminum rods with 22 mm in diameter (p/D=1.45). The natural frequency of rod vibration is about 30Hz. The result indicated a diversion of observed trend in vibration behavior depending on two-phase flow patterns either bubbly flow or churn flow. Specifically, in churn flow, the fluid elastic vibration has been observed to occur when the frequency in void fraction fluctuation approached to the natural frequency of the rods, but this was not the case in fluid elastic vibration in bubbly flow. This fact suggests the existence of mechanisms closely coupled with two-phase flow structures depending on the flow patterns, that is, static two-phase character-controlled mechanism in bubbly flow and dynamic character- controlled in churn flow

  17. Charmless two-body B(s)→VP decays in soft collinear effective theory

    International Nuclear Information System (INIS)

    Wang Wei; Wang Yuming; Yang Deshan; Lue Caidian

    2008-01-01

    We provide the analysis of charmless two-body B→VP decays under the framework of the soft collinear effective theory (SCET), where V(P) denotes a light vector (pseudoscalar) meson. Besides the leading power contributions, some power corrections (chiraly enhanced penguins) are also taken into account. Using the current available B→PP and B→VP experimental data on branching fractions and CP asymmetry variables, we find two kinds of solutions in χ 2 fit for the 16 nonperturbative inputs which are essential in the 87 B→PP and B→VP decay channels. Chiraly enhanced penguins can change several charming penguins sizably, since they share the same topology. However, most of the other nonperturbative inputs and predictions on branching ratios and CP asymmetries are not changed too much. With the two sets of inputs, we predict the branching fractions and CP asymmetries of other modes especially B s →VP decays. The agreements and differences with results in QCD factorization and perturbative QCD approach are analyzed. We also study the time-dependent CP asymmetries in channels with CP eigenstates in the final states and some other channels such as B 0 /B 0 →π ± ρ ± and B s 0 /B s 0 →K ± K* ± . In the perturbative QCD approach, the (S-P)(S+P) penguins in annihilation diagrams play an important role. Although they have the same topology with charming penguins in SCET, there are many differences between the two objects in weak phases, magnitudes, strong phases, and factorization properties.

  18. Underlying event background in two-pion correlations in p + p collisions at √ s = 0.9 and 7 TeV

    International Nuclear Information System (INIS)

    Kisiel, A.

    2011-01-01

    When analyzing two-particle correlations for identical pions in p + p collisions at √ s = 0.9 and 7 TeV, significant background correlation structures are observed. The structures are also observed for pairs of nonidentical pions and are reproduced by Monte-Carlo simulations. We analyze these structures quantitatively and propose methods to account for their impact on the system sizes extracted from the fits to the identical pion correlation functions

  19. Garvey-Kelson mass relations and n-p interaction

    International Nuclear Information System (INIS)

    Gao Zaochun; Meng Jie; Chen Yongshou

    2001-01-01

    Two Garvey-Kelson mass relations are found to be directly related to the n-p interaction. In the case of the same nuclear core, the neutron-proton interaction energy between two neutrons and one proton ε 2n-1p is experimentally found to be close to that between one neutron and two protons ε 1n-2p , which is equivalent to the first Garvey-Kelson mass relation. The sum of ε 2n-1p and ε 1n-2p is close to the n-p interaction energy between two neutrons and two protons ε 2n-2p , which leads to the second Garvey-Kelson mass relation. An explanation of these two n-p interaction relations is presented. It is shown that both of these mass relations hold more accurately when the core is an even-even core

  20. The 5s25p2 - (5s25p5d + 5s5p3 + 5s25p6s + 5s25p7s) transitions in Sb II and 5s25p - (5s5p2 + 5s2nl) transitions in Sb III

    International Nuclear Information System (INIS)

    Arcimowicz, B.; Joshi, Y.N.; Kaufman, V.

    1989-01-01

    The spectrum of antimony was photographed in the 575-2300 A region (1A 10 -10 m) using a hollow cathode and a triggered spark source. The analysis of the 5s 2 5p 2 - (5s 2 5p5d + 5s5p 3 + 5s 2 5p6s + 5s 2 5p7s) transitions in Sb II spectrum was revised and interpreted on the basis of multiconfiguration interaction calculations. Accurate wavelength measurements of Sb III lines lead to a revised ground-state 5s 2 5p 2 P interval value of 6574.5 cm -1 . (author). 15 refs., 9 tabs., 1 fig

  1. The phase diagram of water at negative pressures: virtual ices.

    Science.gov (United States)

    Conde, M M; Vega, C; Tribello, G A; Slater, B

    2009-07-21

    The phase diagram of water at negative pressures as obtained from computer simulations for two models of water, TIP4P/2005 and TIP5P is presented. Several solid structures with lower densities than ice Ih, so-called virtual ices, were considered as possible candidates to occupy the negative pressure region of the phase diagram of water. In particular the empty hydrate structures sI, sII, and sH and another, recently proposed, low-density ice structure. The relative stabilities of these structures at 0 K was determined using empirical water potentials and density functional theory calculations. By performing free energy calculations and Gibbs-Duhem integration the phase diagram of TIP4P/2005 was determined at negative pressures. The empty hydrates sII and sH appear to be the stable solid phases of water at negative pressures. The phase boundary between ice Ih and sII clathrate occurs at moderate negative pressures, while at large negative pressures sH becomes the most stable phase. This behavior is in reasonable agreement with what is observed in density functional theory calculations.

  2. Complete factorial design to adjust pH and sugar concentrations in the inoculum phase of Ralstonia solanacearum to optimize P(3HB production.

    Directory of Open Access Journals (Sweden)

    Karine Laste Macagnan

    Full Text Available Poly(3-hydroxybutyrate (P(3HB is a biodegradable plastic biopolymer that accumulates as lipophilic inclusions in the cytoplasm of some microorganisms. The biotechnological process by which P(3HB is synthesized occurs in two phases. The first phase involves cell growth in a complex culture medium, while the second phase involves polymer accumulation in the presence of excess carbon sources. As such, the efficiency of the second phase depends on the first phase. The aim of this study was to evaluate culture media with different concentrations of sucrose and glucose and different pH values in the inoculum phase of Ralstonia solanacearum RS with the intention of identifying methods by which the biomass yield could be increased, subsequently enhancing the yield of P(3HB. The culture medium was formulated according to the experimental planning type of central composite rotational design 22. The independent variables were pH and sugar concentration (sucrose and glucose, and the dependent variables were OD600nm, dry cell weight (DCW, and P(3HB yield. The highest cell growth, estimated by the OD600nm (20.6 and DCW (5.35 values, was obtained when sucrose was used in the culture medium at a concentration above 35 g.L-1 in combination with an acidic pH. High polymer (45% accumulation was also achieved under these conditions. Using glucose, the best results for OD600nm (12.5 and DCW (2.74 were also obtained at acidic pH but with a sugar concentration at the minimum values evaluated. Due to the significant accumulation of polymer in the cells that were still in the growth phase, the accumulating microorganism P(3HB Ralstonia solanacearum RS can be classified as having type II metabolism in relation to the polymer accumulation phase, which is different from other Ralstonia spp. studied until this time.

  3. Cytochrome P450s and molecular epidemiology

    Science.gov (United States)

    Gonzalez, Frank J.; Gelboin, Harry V.

    1993-03-01

    Cytochrome P450 (P450) represent a superfamily of heme-containing monooxygenases that are found throughout the animal and plant kingdoms and in many microorganisms. A number of these enzymes are involved in biosynthetic pathways of steroid synthesis but in mammals the vast majority of P450s function to metabolize foreign chemicals or xenobiotics. In the classical phase I reactions on the latter, a membrane-bound P450 will hydroxylate a compound, usually hydrophobic in nature, and the hydroxyl group will serve as a substrate for the various transferases or phase II enzymes that attach hydrophilic substituents such as glutathione, sulfate or glucuronic acid. Some chemicals, however, are metabolically-activated by P450s to electrophiles capable of reacting with cellular macromolecules. The cellular concentrations of the chemical and P450, reactivity of the active metabolite with nucleic acid and the repairability of the resultant adducts, in addition to the nature of the cell type, likely determines whether a chemical will be toxic and kill the cell or will transform the cell. Immunocorrelative and cDNA-directed expression have been used to define the substrate specificities of numerous human P450s. Levels of expression of different human P450 forms have been measured by both in vivo and in vitro methodologies leading to the realization that a large degree of interindividual differences occur in P450 expression. Reliable procedures for measuring P450 expression in healthy and diseased subjects will lead to prospective and case- cohort studies to determine whether interindividual differences in levels of P450 are associated with susceptibility or resistance to environmentally-based disease.

  4. Determination of the single-phase constitutive relations of α/β dual phase TC6 titanium alloy

    Energy Technology Data Exchange (ETDEWEB)

    Shi, Ran; Li, Guoju [School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081 (China); National Key Laboratory of Science and Technology on Materials Under Shock and Impact, Beijing 100081 (China); Nie, Zhihua [School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081 (China); Fan, Qunbo, E-mail: fanqunbo@bit.edu.cn [School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081 (China); National Key Laboratory of Science and Technology on Materials Under Shock and Impact, Beijing 100081 (China)

    2016-10-15

    The constitutive relations of α and β phases in a TC6 titanium alloy were determined by implementing a two-phase elastic-plastic self-consistent (EPSC) framework combined with the evolution of lattice strains; these strains were obtained via in-situ tensile loading synchrotron-based x-ray diffraction experiments. It was found that the {200}{sub β} reflection has the lowest stiffness and load partitions prior to the α phase during the elastic loading stage in this alloy. The simulated parameters including the diffraction elastic constant and initial yield stress of lattice reflections exhibited satisfactory correspondence with the experimental results. Further analysis of the characteristics of the Schmid Factor (SF) distributions of the main slip systems revealed that the elastic-plastic transition process in the α phase occurs over a prolonged period. In contrast, the β phase undergoes a transient process owing to its relatively more concentrated SF frequency distributions, than those of the α phase. In addition, the fitted stress-strain curve of each phase was compared with the measured macro stress-strain curve obtained from the in-situ experiment. It revealed Young's moduli of 110.3 GPa and 104.5 GPa, and yield stresses of 877.8 MPa and 969 MPa, for the α and β phases, respectively.

  5. Optical study of phase transitions in single-crystalline RuP

    Science.gov (United States)

    Chen, R. Y.; Shi, Y. G.; Zheng, P.; Wang, L.; Dong, T.; Wang, N. L.

    2015-03-01

    RuP single crystals of MnP-type orthorhombic structure were synthesized by the Sn flux method. Temperature-dependent x-ray diffraction measurements reveal that the compound experiences two structural phase transitions, which are further confirmed by enormous anomalies shown in temperature-dependent resistivity and magnetic susceptibility. Particularly, the resistivity drops monotonically upon temperature cooling below the second transition, indicating that the material shows metallic behavior, in sharp contrast with the insulating ground state of polycrystalline samples. Optical conductivity measurements were also performed in order to unravel the mechanism of these two transitions. The measurement revealed a sudden reconstruction of band structure over a broad energy scale and a significant removal of conducting carriers below the first phase transition, while a charge-density-wave-like energy gap opens below the second phase transition.

  6. Tungsten phosphanylarylthiolato complexes [W{PhP(2-SC6H4)2-kappa3S,S',P} 2] and [W{P(2-SC6H4)3-kappa4S,S',S",P}2]: synthesis, structures and redox chemistry.

    Science.gov (United States)

    Hildebrand, Alexandra; Lönnecke, Peter; Silaghi-Dumitrescu, Luminita; Hey-Hawkins, Evamarie

    2008-09-14

    PhP(2-SHC6H4)2 (PS2H2) reacts with WCl6 with reduction of tungsten to give the air-sensitive tungsten(IV) complex [W{PhP(2-SC6H4)2-kappa(3)S,S',P}2] (1). 1 is oxidised in air to [WO{PhPO(2-SC6H4)2-kappa(3)S,S',O}{PhP(2-SC6H4)2-kappa(3)S,S',P}] (2). The attempted synthesis of 2 by reaction of 1 with iodosobenzene as oxidising agent was unsuccessful. [W{P(2-SC6H4)3-kappa(4)S,S',S",P}2] (3) was formed in the reaction of P(2-SHC6H4)3 (PS3H3) with WCl6. The W(VI) complex 3 contains two PS3(3-) ligands, each coordinated in a tetradentate fashion resulting in a tungsten coordination number of eight. The reaction of 3 with AgBF4 yields the dinuclear tungsten complex [W2{P(2-SC6H4)3-kappa(4)S,S',S",P}3]BF4 (4). Complexes 1-4 were characterised by spectral methods and X-ray structure determination.

  7. Sphingosine-1-Phosphate (S1P)-Related Response of Human Conjunctival Fibroblasts After Filtration Surgery for Glaucoma.

    Science.gov (United States)

    Aoyama-Araki, Yuka; Honjo, Megumi; Uchida, Takatoshi; Yamagishi, Reiko; Kano, Kuniyuki; Aoki, Junken; Aihara, Makoto

    2017-04-01

    To investigate levels of sphingosine-1-phosphate (S1P) in aqueous fluid samples taken before and after filtration surgery and S1P-induced human conjunctival fibroblast (HCF) responses. Levels of S1P and its related sphingophospholipids in aqueous fluid obtained immediately before and after filtration surgery were determined by liquid chromatography-tandem mass spectrometry. HCFs were used for all in vitro experiments. The expression of five S1P receptor subtypes in HCFs was examined by quantitative real-time PCR. The effect of S1P and receptor-specific antagonists on HCF viability and cell migration was assessed by WST-1 assay and scratch migration assay, respectively. Differentiation to myofibroblasts and extracellular matrix production was evaluated by examining changes in F-actin, α-smooth muscle actin (αSMA), and collagen expression with immunocytochemistry, Western blotting, and collagen accumulation assay, respectively. No significant S1P levels in the aqueous fluid samples were detectable immediately before surgery, but postoperative levels of several lysophospholipids, including S1P, dehydro-S1P, and sphingosine, were significantly increased to bioactive concentrations in aqueous fluid in the blebs (P S1P receptor subtypes was detected in HCFs. Although S1P levels did not influence HCF proliferation, S1P enhanced cell migration, which could be inhibited by the S1P2 antagonist JTE 013. F-actin, αSMA, and collagen expression was significantly increased by S1P stimulation and was reduced by JTE 013. Bioactive S1P concentrations were present in the aqueous fluid at the end of filtration surgery. S1P activated HCFs via S1P2 receptors. These results revealed the potential of S1P2 antagonists in preventing scarring after glaucoma filtration surgery.

  8. Application of two-phase flow for cooling of hybrid microchannel PV cells: A comparative study

    International Nuclear Information System (INIS)

    Valeh-e-Sheyda, Peyvand; Rahimi, Masoud; Karimi, Ebrahim; Asadi, Masomeh

    2013-01-01

    Highlights: ► Showing cooling potential of gas–liquid two-phase flow in microchannels for PV cell. ► Introducing the concept of using slug flow in microchannels for cooling of PV cells. ► In single-phase flow, increasing the liquid flow rate enhances the PV power. ► Showing that in two-phase flow the output power related the fluid flow regime. ► By coupling PV and microchannel an increase up to 38% in output power was observed. - Abstract: This paper reports the experimental data from performance of two-phase flows in a small hybrid microchannel solar cell. Using air and water as two-phase fluid, the experiments were conducted at indoor condition in an array of rectangular microchannels with a hydraulic diameter of 0.667 mm. The gas superficial velocity ranges were between 0 and 3.27 m s −1 while liquid flow rate was 0.04 m s −1 . The performance analysis of the PV cell at slug and transitional slug/annular flow regimes are the focus of this study. The influence of two-phase working fluid on PV cell cooling was compared with single-phase. In addition, the great potential of slug flow for heat removal enhancement in PV/T panel was investigated. The obtained data showed the proposed hybrid system could substantially increases the output power of PV solar cells

  9. Mathematical modeling of disperse two-phase flows

    CERN Document Server

    Morel, Christophe

    2015-01-01

    This book develops the theoretical foundations of disperse two-phase flows, which are characterized by the existence of bubbles, droplets or solid particles finely dispersed in a carrier fluid, which can be a liquid or a gas. Chapters clarify many difficult subjects, including modeling of the interfacial area concentration. Basic knowledge of the subjects treated in this book is essential to practitioners of Computational Fluid Dynamics for two-phase flows in a variety of industrial and environmental settings. The author provides a complete derivation of the basic equations, followed by more advanced subjects like turbulence equations for the two phases (continuous and disperse) and multi-size particulate flow modeling. As well as theoretical material, readers will discover chapters concerned with closure relations and numerical issues. Many physical models are presented, covering key subjects including heat and mass transfers between phases, interfacial forces and fluid particles coalescence and breakup, a...

  10. Liquid-phase epitaxy of InGaAsP solid solutions on profiled substrates of InP(100)

    International Nuclear Information System (INIS)

    Dvoryankin, V.F.; Kaevitser, L.R.; Komarov, A.A.; Telegin, A.A.; Khusid, L.B.; Chernushin, M.D.

    1990-01-01

    Peculiarities of selective growth of InGaAsP solid solutions under liquid-phase epitaxy in shallow grooves are considered. InGaAsP crystals grown in grooves oriented along crystallografic [110] and [011] directions are determined to trend to equilibrium form under two-phase epitaxy, while wedge-shaped form of In 0.77 Ga 0.23 As 0.53 P 0.45 and In 0.53 P o.45 and IN 0.59 Ga 0.41 As 0.83 P 0.12 epitaxial layers obtained in grooves is determined by their composition only and does not depend on groove configuration

  11. Mathematical well-posedness of a two-fluid equations for bubbly two-phase flows

    International Nuclear Information System (INIS)

    Okawa, Tomio; Kataoka, Isao

    2000-01-01

    It is widely known that two-fluid equations used in most engineering applications do not satisfy the necessary condition for being mathematical well-posed as initial-value problems. In the case of stratified two-phase flows, several researchers have revealed that differential models satisfying the necessary condition are to be derived if the pressure difference between the phases is related to the spatial gradient of the void fraction through the effects of gravity or surface tension. While, in the case of dispersed two-phase flows, no physically reasonable method to derive mathematically well-posed two-fluid model has been proposed. In the present study, particularly focusing on the effect of interfacial pressure terms, we derived the mathematically closed form of the volume-averaged two-fluid model for bubbly two-phase flows. As a result of characteristic analyses, it was shown that the proposed two-fluid equations satisfy the necessary condition of mathematical well-posedness if the void fraction is sufficiently small. (author)

  12. On mechanism of substructure formation in SmS during isomorphic phase transformations

    International Nuclear Information System (INIS)

    Aptekar', I.L.; Ivanov, V.I.; Tonkov, E.Yu.; Shmyt'ko, I.M.

    1986-01-01

    X-ray diffraction study of substructure characteristics of SmS samples subjected to treatment at different temrerature and pressure in media with different viscosity ( graphite, silicon oil) for realization of P-M-P transformations ( p-semiconductor phase, M - high pressure phase) is performed. It is assumed that with M - phase formation P - matrix volume relaxation delays, therefore the new phase particles occupy smaller volume than the initial matrix which causes the M - phase disorientation. The difference between the phase transformation rate and deformation rate under the pressure in media with various viscosity results in arising different substructural characteristics

  13. Study of ln s Physics in $\\bar{p}p$ Interactions at the Split Field Magnet

    CERN Multimedia

    2002-01-01

    This experiment uses the Split Field Magnet detector to investigate the low p^t, ``ln~s'', type of interactions that dominate the @*p cross-section. Systematic comparisons will be made to pp interactions. \\\\ \\\\ Specific areas to be studied include elastic scattering in the regions 0.05 $<$ !t! $<$ 0.8 GeV|2 and 0.8 $<$ !t! $<$ 4.0 GeV|2, and the use of a minimum bias trigger to study topological cross-sections, inclusive spectra, and two-body correlations. Some specialized triggers, run simultaneously with the high t elastic scattering trigger, are being studied. Examples are a trigger requiring Cerenkov identification in a limited region of phase space, and a trigger to select diffractively produced events.

  14. Two-phase flow characteristics analysis code: MINCS

    International Nuclear Information System (INIS)

    Watanabe, Tadashi; Hirano, Masashi; Akimoto, Masayuki; Tanabe, Fumiya; Kohsaka, Atsuo.

    1992-03-01

    Two-phase flow characteristics analysis code: MINCS (Modularized and INtegrated Code System) has been developed to provide a computational tool for analyzing two-phase flow phenomena in one-dimensional ducts. In MINCS, nine types of two-phase flow models-from a basic two-fluid nonequilibrium (2V2T) model to a simple homogeneous equilibrium (1V1T) model-can be used under the same numerical solution method. The numerical technique is based on the implicit finite difference method to enhance the numerical stability. The code structure is highly modularized, so that new constitutive relations and correlations can be easily implemented into the code and hence evaluated. A flow pattern can be fixed regardless of flow conditions, and state equations or steam tables can be selected. It is, therefore, easy to calculate physical or numerical benchmark problems. (author)

  15. A new method for the experimental determination of three-phase relative permeabilities

    International Nuclear Information System (INIS)

    Perez Carrillo, Edgar Ricardo; Jose Francisco Zapata Arango; Santos Santos, Nicolas

    2008-01-01

    Petroleum reservoirs under primary, secondary or tertiary recovery processes usually experience simultaneous flow of three fluids phases (oil, water and gas). Reports on some mathematical models for calculating three-phase relative permeability are available in the Literature. Nevertheless, many of these models were designed based on certain experimental conditions and reservoir rocks and fluids. Therefore, special care has to be taken when applying them to specific reservoirs. At the laboratory level, three-phase relative permeability can be calculated using experimental unsteady-state or steady state methodologies. This paper proposes an unsteady-state methodology to evaluate three-phase relative permeability using the equipment available at the petrophysical analysis Laboratory of the Instituto Colombiano del Petroleo (ICP) of Ecopetrol S.A. Improvements to the equipment were effected in order to achieve accuracy in the unsteady-state measurement of three-phase relative permeability. The target of improvements was directed toward to the attainment of two objectives:1) the modification of the equipment to obtain more reliable experimental data and 2) the appropriate interpretation of the data obtained. Special attention was given to the differential pressure and uncertainty measurement in the determination of fluid saturation in the rock samples. Three experiments for three-phase relative permeability were conducted using a sample A and reservoir rock from the Colombian Foothills. Fluid tests included the utilization of synthetic brine, mineral oil, reservoir crude oil and nitrogen. Two runs were conducted at the laboratory conditions while one run was conducted at reservoir conditions. Experimental results of these tests were compared using 16 mathematical models of three-phase relative permeability. For the three-phase relative permeability to oil, the best correlations between experimental data and tests using Blunt, Hustad Hasen, and Baker's models were

  16. Role of relativity in high-pressure phase transitions of thallium.

    Science.gov (United States)

    Kotmool, Komsilp; Chakraborty, Sudip; Bovornratanaraks, Thiti; Ahuja, Rajeev

    2017-02-20

    We demonstrate the relativistic effects in high-pressure phase transitions of heavy element thallium. The known first phase transition from h.c.p. to f.c.c. is initially investigated by various relativistic levels and exchange-correlation functionals as implemented in FPLO method, as well as scalar relativistic scheme within PAW formalism. The electronic structure calculations are interpreted from the perspective of energetic stability and electronic density of states. The full relativistic scheme (FR) within L(S)DA performs to be the scheme that resembles mostly with experimental results with a transition pressure of 3 GPa. The s-p hybridization and the valence-core overlapping of 6s and 5d states are the primary reasons behind the f.c.c. phase occurrence. A recent proposed phase, i.e., a body-centered tetragonal (b.c.t.) phase, is confirmed with a small distortion from the f.c.c. phase. We have also predicted a reversible b.c.t. → f.c.c. phase transition at 800 GPa. This finding has been suggested that almost all the III-A elements (Ga, In and Tl) exhibit the b.c.t. → f.c.c. phase transition at extremely high pressure.

  17. Two dimensional MoS{sub 2}/graphene p-n heterojunction diode: Fabrication and electronic characteristics

    Energy Technology Data Exchange (ETDEWEB)

    Su, Wei-Jhih [Graduate Institute of Electro-Optical Engineering, National Taiwan University of Science and Technology, 43, Section 4, Keelung Road, Taipei 10607, Taiwan (China); Chang, Hsuan-Chen [Department of Electronic and Computer Engineering, National Taiwan University of Science and Technology, 43, Section 4, Keelung Road, Taipei 10607, Taiwan (China); Shih, Yi-Ting [Graduate Institute of Electro-Optical Engineering, National Taiwan University of Science and Technology, 43, Section 4, Keelung Road, Taipei 10607, Taiwan (China); Wang, Yi-Ping [Department of Electronic and Computer Engineering, National Taiwan University of Science and Technology, 43, Section 4, Keelung Road, Taipei 10607, Taiwan (China); Hsu, Hung-Pin [Department of Electronic Engineering, Ming Chi University of Technology, 84 Gungjuan Road, New Taipei City 24301, Taiwan (China); Huang, Ying-Sheng [Graduate Institute of Electro-Optical Engineering, National Taiwan University of Science and Technology, 43, Section 4, Keelung Road, Taipei 10607, Taiwan (China); Department of Electronic and Computer Engineering, National Taiwan University of Science and Technology, 43, Section 4, Keelung Road, Taipei 10607, Taiwan (China); Lee, Kuei-Yi, E-mail: kylee@mail.ntust.edu.tw [Graduate Institute of Electro-Optical Engineering, National Taiwan University of Science and Technology, 43, Section 4, Keelung Road, Taipei 10607, Taiwan (China); Department of Electronic and Computer Engineering, National Taiwan University of Science and Technology, 43, Section 4, Keelung Road, Taipei 10607, Taiwan (China)

    2016-06-25

    Molybdenum disulfide (MoS{sub 2}) films are currently the most potential semiconductor materials of the two-dimensional nano-material heterojunction. Few-layer MoS{sub 2} is an n-type semiconductor that has good mechanical strength, high carrier mobility, and has similar thickness as graphene. Graphene is presently the thinnest two-dimensional material with good thermal conductivity and high carrier mobility. The graphene Fermi level can be precisely controlled using the oxygen adsorption. Therefore, graphene can be tuned from zero-gap to p-type semiconductor material using the amount of adsorbed oxygen. In this study we combine few-layer MoS{sub 2} and graphene to produce a heterojunction and exhaustively study the interface properties for heterojunction diode application. According to the results, the MoS{sub 2} band-gap increases with decreasing thickness. The I–V characteristics of the MoS{sub 2}/Graphene p-n junction diodes can be precisely tuned by adjusting different thicknesses of the MoS{sub 2} films. By applying our fabricating method, MoS{sub 2}/Graphene heterojunction diode can be easily constructed and have potential to different applications. - Highlights: • We controlled the layer thickness of MoS{sub 2} by different exfoliation times. • We presented Raman scattering of MoS{sub 2} and define their layers number. • The few-layer MoS{sub 2}/graphene pn junction diode was synthesized. • We measured the device current and voltage characteristics. • The built-in potential barrier could be adjusted by controlling MoS{sub 2} thicknesses.

  18. Stochastic modelling of two-phase flows including phase change

    International Nuclear Information System (INIS)

    Hurisse, O.; Minier, J.P.

    2011-01-01

    Stochastic modelling has already been developed and applied for single-phase flows and incompressible two-phase flows. In this article, we propose an extension of this modelling approach to two-phase flows including phase change (e.g. for steam-water flows). Two aspects are emphasised: a stochastic model accounting for phase transition and a modelling constraint which arises from volume conservation. To illustrate the whole approach, some remarks are eventually proposed for two-fluid models. (authors)

  19. Two-phase flow patterns and their relationship to two-phase heat transfer

    International Nuclear Information System (INIS)

    Hewitt, G.F.

    1977-01-01

    The objective of this lecture was to discuss the general nature of two phase flows, to define the various regimes of flow and to discuss the influence of these regimes on the heat transfer processes taking place. The methods of regime delineation are briefly described and regime descriptions introduced for both vertical and horizontal flows in tubes. ''Flow regime maps'' have been widely used as an aid to determination of the regime which occurs in a given situation. Some of the more widely used maps are described and the limitations of this approach discussed. There have been many attempts to obtain a better phenomenological description of two phase flow patterns. In this lecture, these attempts will be reviewed in the context of the bubble/plug, plug/churn and churn/annular flow transitions in vertical flow. The latter two transitions are related to the flooding/flow reversal phenomena. For horizontal flows, recent work on the onset of slugging will be reviewed. In flows with evaporation or condensation, the situation is influenced by departures from thermodynamic equilibrium and the types of departure observed are discuss briefly. Flow patterns and their relationships with heat transfer regimes are then reviewed for the case of condensation in horizontal tubes and evaporation in vertical tubes

  20. Two-phase flow induced parametric vibrations in structural systems

    International Nuclear Information System (INIS)

    Hara, Fumio

    1980-01-01

    This paper is divided into two parts concerning piping systems and a nuclear fuel pin system. The significant experimental results concerning the random vibration induced in an L-shaped pipe by air-water two-phase flow and the theoretical analysis of the vibration are described in the first part. It was clarified for the first time that the parametric excitation due to the periodic changes of system mass, centrifugal force and Coriolis force was the mechanism of exciting the vibration. Moreover, the experimental and theoretical analyses of the mechanism of exciting vibration by air-water two-phase flow in a straight, horizontal pipe were carried out, and the first natural frequency of the piping system was strongly related to the dominant frequency of void signals. The experimental results on the vibration of a nuclear fuel pin model in parallel air-water two-phase flow are reported in the latter part. The relations between vibrational strain variance and two-phase flow velocity or pressure fluctuation, and the frequency characteristics of vibrational strain variance were obtained. The theoretical analysis of the dynamic interaction between air-water two-phase flow and a fuel pin structure, and the vibrational instability of fuel pins in alternate air and water slugs or in large bubble flow are also reported. (Kako, I.)

  1. Fluid-elastic force measurements acting on a tube bundle in two-phase cross flow

    International Nuclear Information System (INIS)

    Inada, Fumio; Kawamura, Koji; Yasuo, Akira

    1996-01-01

    Fluid-elastic force acting on a square tube bundle of P/D = 1.47 in air-water two-phase cross flow was measured to investigate the characteristics and to clarify whether the fluid elastic vibration characteristics could be expressed using two-phase mixture characteristics. Measured fluid elastic forces were separated into fluid-elastic force coefficients such as added mass, added stiffness, and added damping coefficient. The added damping coefficient was separated into a two-phase damping and a flow-dependent component as in previous research (Carlucci, 1981 and 1983; Pettigrew, 1994). These coefficients were nondimensionalized with two-phase mixture characteristics such as void fraction, mixture density and mixture velocity, which were obtained using the drift-flux model with consideration given to the model. The result was compared with the result obtained with the homogeneous model. It was found that fluid-elastic force coefficients could be expressed with two-phase flow mixture characteristics very well in the experimental result, and that better result can be derived using the slip model as compared to the homogeneous model. Added two-phase flow, which could be expressed as a function of void fraction, where two-phase damping was nondimensionalized with the relative velocity between the gas and liquid phases used as a reference velocity. Using these, the added stiffness coefficient and flow-dependent component of damping could be expressed very well as a function of nondimensional mixture velocity

  2. Two-phase strategy of neural control for planar reaching movements: II--relation to spatiotemporal characteristics of movement trajectory.

    Science.gov (United States)

    Rand, Miya K; Shimansky, Yury P

    2013-09-01

    In the companion paper utilizing a quantitative model of optimal motor coordination (Part I, Rand and Shimansky, in Exp Brain Res 225:55-73, 2013), we examined coordination between X and Y movement directions (XYC) during reaching movements performed under three prescribed speeds, two movement amplitudes, and two target sizes. The obtained results indicated that the central nervous system (CNS) utilizes a two-phase strategy, where the initial and the final phases correspond to lower and higher precision of information processing, respectively, for controlling goal-directed reach-type movements to optimize the total cost of task performance including the cost of neural computations. The present study investigates how two different well-known concepts used for describing movement performance relate to the concepts of optimal XYC and two-phase control strategy. First, it is examined to what extent XYC is equivalent to movement trajectory straightness. The data analysis results show that the variability, the movement trajectory's deviation from the straight line, increases with an increase in prescribed movement speed. In contrast, the dependence of XYC strength on movement speed is opposite (in total agreement with an assumption of task performance optimality), suggesting that XYC is a feature of much higher level of generality than trajectory straightness. Second, it is tested how well the ballistic and the corrective components described in the traditional concept of two-component model of movement performance match with the initial and the final phase of the two-phase control strategy, respectively. In fast reaching movements, the percentage of trials with secondary corrective submovement was smaller under larger-target shorter-distance conditions. In slower reaching movements, meaningful parsing was impossible due to massive fluctuations in the kinematic profile throughout the movement. Thus, the parsing points determined by the conventional submovement analysis

  3. A void fraction model for annular two-phase flow

    Energy Technology Data Exchange (ETDEWEB)

    Tandon, T.N.; Gupta, C.P.; Varma, H.K.

    1985-01-01

    An analytical model has been developed for predicting void fraction in two-phase annular flow. In the analysis, the Lockhart-Martinelli method has been used to calculate two-phase frictional pressure drop and von Karman's universal velocity profile is used to represent the velocity distribution in the annular liquid film. Void fractions predicted by the proposed model are generally in good agreement with a available experimental data. This model appears to be as good as Smith's correlation and better than the Wallis and Zivi correlations for computing void fraction.

  4. P-wave holographic superconductor/insulator phase transitions affected by dark matter sector

    International Nuclear Information System (INIS)

    Rogatko, Marek; Wysokinski, Karol I.

    2016-01-01

    The holographic approach to building the p-wave superconductors results in three different models: the Maxwell-vector, the SU(2) Yang-Mills and the helical. In the probe limit approximation, we analytically examine the properties of the first two models in the theory with dark matter sector. It turns out that the effect of dark matter on the Maxwell-vector p-wave model is the same as on the s-wave superconductor studied earlier. For the non-Abelian model we study the phase transitions between p-wave holographic insulator/superconductor and metal/superconductor. Studies of marginally stable modes in the theory under consideration allow us to determine features of p-wave holographic droplet in a constant magnetic field. The dependence of the superconducting transition temperature on the coupling constant α to the dark matter sector is affected by the dark matter density ρ_D. For ρ_D>ρ the transition temperature is a decreasing function of α. The critical chemical potential μ_c for the quantum phase transition between insulator and metal depends on the chemical potential of dark matter μ_D and for μ_D=0 is a decreasing function of α.

  5. Spectral Analysis of Instantaneous Power in Single-phase and Three-phase Systems with Use of p-q-r Theory

    DEFF Research Database (Denmark)

    Kim, Hyosung; Blaabjerg, Frede; Bak-Jensen, Birgitte

    2002-01-01

    This paper proposes a novel power compensation algorithm in three-phase four-wire systems by using p-q-r theory. The p-q-r theory is compared with two previous instantaneous power theories, p-q theory and cross-vector theory. The p-q-r theory provides two-degrees of freedom to control the system...

  6. Modeling and numerical study of two phase flow

    International Nuclear Information System (INIS)

    Champmartin, A.

    2011-01-01

    This thesis describes the modelization and the simulation of two-phase systems composed of droplets moving in a gas. The two phases interact with each other and the type of model to consider directly depends on the type of simulations targeted. In the first part, the two phases are considered as fluid and are described using a mixture model with a drift relation (to be able to follow the relative velocity between the two phases and take into account two velocities), the two-phase flows are assumed at the equilibrium in temperature and pressure. This part of the manuscript consists of the derivation of the equations, writing a numerical scheme associated with this set of equations, a study of this scheme and simulations. A mathematical study of this model (hyperbolicity in a simplified framework, linear stability analysis of the system around a steady state) was conducted in a frame where the gas is assumed baro-tropic. The second part is devoted to the modelization of the effect of inelastic collisions on the particles when the time of the simulation is shorter and the droplets can no longer be seen as a fluid. We introduce a model of inelastic collisions for droplets in a spray, leading to a specific Boltzmann kernel. Then, we build caricatures of this kernel of BGK type, in which the behavior of the first moments of the solution of the Boltzmann equation (that is mass, momentum, directional temperatures, variance of the internal energy) are mimicked. The quality of these caricatures is tested numerically at the end. (author) [fr

  7. Investigation of Power Losses of Two-Stage Two-Phase Converter with Two-Phase Motor

    Directory of Open Access Journals (Sweden)

    Michal Prazenica

    2011-01-01

    Full Text Available The paper deals with determination of losses of two-stage power electronic system with two-phase variable orthogonal output. The simulation is focused on the investigation of losses in the converter during one period in steady-state operation. Modeling and simulation of two matrix converters with R-L load is shown in the paper. The simulation results confirm a very good time-waveform of the phase current and the system seems to be suitable for low-cost application in automotive/aerospace industries and in application with high frequency voltage sources.

  8. An Experimental Study of Two-Phase Pulse Flushing Technology in Water Distribution Systems

    Directory of Open Access Journals (Sweden)

    Zhaozhao Tang

    2017-12-01

    Full Text Available The deterioration of drinking water during distribution process is caused by many factors. The microorganisms and substances peeling off from the “growth-ring” make the secondary pollution in drinking water distribution systems. To reduce the secondary pollution, two-phase pulse flushing technology is introduced to quickly remove the “growth-ring”. In this study, experiment is undertaken for investigating the efficiency of the two-phase pulse flushing and finding the best setting combination. A case study is undertaken to compare the efficiencies between the two-phase pulse and the single-phase flushing. The best setting combination of the two-phase pulse flushing is at the frequency 4 s–6 s (air inflow time is 4 s and air cut off time is 6 s and the round air inflow nozzle is set at the bottom of the pipe. Two-phase pulse flushing technology can save 95% of water and 6 h 40 min flushing time.

  9. Two-phase velocity measurements around cylinders using particle image velocimetry

    Energy Technology Data Exchange (ETDEWEB)

    Hassan, Y.A.; Philip, O.G.; Schmidl, W.D. [Texas A& M Univ., College Station, TX (United States)] [and others

    1995-09-01

    The particle Image Velocimetry flow measurement technique was used to study both single-phase flow and two-phase flow across a cylindrical rod inserted in a channel. First, a flow consisting of only a single-phase fluid was studied. The experiment consisted of running a laminar flow over four rods inserted in a channel. The water flow rate was 126 cm{sup 3}/s. Then a two-phase flow was studied. A mixture of water and small air bubbles was used. The water flow rate was 378 cm{sup 3}/s and the air flow rate was approximately 30 cm{sup 3}/s. The data are analyzed to obtain the velocity fields for both experiments. After interpretation of the velocity data, forces acting on a bubble entrained by the vortex were calculated successfully. The lift and drag coefficients were calculated using the velocity measurements and the force data.

  10. Induction of S-phase entry by E2F transcription factors depends on their nuclear localization

    DEFF Research Database (Denmark)

    Müller, H; Moroni, M C; Vigo, E

    1997-01-01

    The E2F transcription factors are essential for regulating the correct timing of activation of several genes whose products are implicated in cell proliferation and DNA replication. The E2Fs are targets for negative regulation by the retinoblastoma protein family, which includes pRB, p107, and p130......, and they are in a pathway that is frequently found altered in human cancers. There are five members of the E2F family, and they can be divided into two functional subgroups. Whereas, upon overexpression, E2F-1, -2, and -3 induce S phase in quiescent fibroblasts and override G1 arrests mediated by the p16INK4A tumor...... suppressor protein or neutralizing antibodies to cyclin D1, E2F-4 and -5 do not. Using E2F-1 and E2F-4 as representatives of the two subgroups, we showed here, by constructing a set of chimeric proteins, that the amino terminus of E2F-1 is sufficient to confer S-phase-inducing potential as well...

  11. Two-phase flow boiling pressure drop in small channels

    International Nuclear Information System (INIS)

    Sardeshpande, Madhavi V.; Shastri, Parikshit; Ranade, Vivek V.

    2016-01-01

    Highlights: • Study of typical 19 mm steam generator tube has been undertaken in detail. • Study of two phase flow boiling pressure drop, flow instability and identification of flow regimes using pressure fluctuations is the main focus of present work. • Effect of heat and mass flux on pressure drop and void fraction was studied. • Flow regimes identified from pressure fluctuations data using FFT plots. • Homogeneous model predicted pressure drop well in agreement. - Abstract: Two-phase flow boiling in small channels finds a variety of applications in power and process industries. Heat transfer, boiling flow regimes, flow instabilities, pressure drop and dry out are some of the key issues related to two-phase flow boiling in channels. In this work, the focus is on pressure drop in two-phase flow boiling in tubes of 19 mm diameter. These tubes are typically used in steam generators. Relatively limited experimental database is available on 19 mm ID tube. Therefore, in the present work, the experimental set-up is designed for studying flow boiling in 19 mm ID tube in such a way that any of the different flow regimes occurring in a steam generator tube (from pre-heating of sub-cooled water to dry-out) can be investigated by varying inlet conditions. The reported results cover a reasonable range of heat and mass flux conditions such as 9–27 kW/m 2 and 2.9–5.9 kg/m 2 s respectively. In this paper, various existing correlations are assessed against experimental data for the pressure drop in a single, vertical channel during flow boiling of water at near-atmospheric pressure. A special feature of these experiments is that time-dependent pressures are measured at four locations along the channel. The steady-state pressure drop is estimated and the identification of boiling flow regimes is done with transient characteristics using time series analysis. Experimental data and corresponding results are compared with the reported correlations. The results will be

  12. Molecular Dissection of the 8 Phase Transcriptional Program Controlled by Cyclin E-P220 NPAT Signaling Pathway

    National Research Council Canada - National Science Library

    Nalepa, Grzegorz; Harper, Jeffrey

    2005-01-01

    .... Recent studies suggest a role for cyclin E/Cdk2 in activation of histone transcription during S phase via the Cajal body-associated protein p22ONPAT, and in addition, p220 can promote S-phase entry...

  13. Review on two-phase flow instabilities in narrow spaces

    International Nuclear Information System (INIS)

    Tadrist, L.

    2007-01-01

    Instabilities in two-phase flow have been studied since the 1950s. These phenomena may appear in power generation and heat transfer systems where two-phase flow is involved. Because of thermal management in small size systems, micro-fluidics plays an important role. Typical processes must be considered when the channel hydraulic diameter becomes very small. In this paper, a brief review of two-phase flow instabilities encountered in channels having hydraulic diameters greater than 10 mm are presented. The main instability types are discussed according to the existing experimental results and models. The second part of the paper examines two-phase flow instabilities in narrow spaces. Pool and flow boiling cases are considered. Experiments as well as theoretical models existing in the literature are examined. It was found that several experimental works evidenced these instabilities meanwhile only limited theoretical developments exist in the literature. In the last part of the paper an interpretation of the two-phase flow instabilities linked to narrow spaces are presented. This approach is based on characteristic time scales of the two-phase flow and bubble growth in the capillaries

  14. Vapor Compressor Driven Hybrid Two-Phase Loop, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — This Small Business Innovation Research Phase I project will demonstrate a vapor compressor driven hybrid two-phase loop technology. The hybrid two-phase loop...

  15. Lupeol induces S-phase arrest and mitochondria-mediated ...

    Indian Academy of Sciences (India)

    48

    Lupeol induces S-phase arrest and mitochondria-mediated apoptosis in cervical cancer cells. Nupoor Prasad1, Akash Sabarwal2, Umesh C. S. Yadav1, Rana P. Singh2,*. 1School of Life Sciences, Central University of Gujarat, Gandhinagar, Gujarat, India. 2Cancer Biology Laboratory, School of Life Sciences, Jawaharlal ...

  16. Split degenerate states and stable p+ip phases from holography

    Energy Technology Data Exchange (ETDEWEB)

    Nie, Zhang-Yu; Zeng, Hui [Kunming University of Science and Technology, Kunming (China); Key Laboratory of Theoretical Physics, Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing (China); Pan, Qiyuan [Hunan Normal Univ., Key Lab. of Low Dimensional Quantum Structures and Quantum Control of Ministry of Education, and Synergetic Innovation Center for Quantum Effects and Applications, Dept. of Physics, Changsha (China); Zeng, Hua-Bi [Yangzhou University, College of Physics Science and Technology, Yangzhou, Jiangsu (China); National Central University, Department of Physics, Chungli (China)

    2017-02-15

    In this paper, we investigate the p+ip superfluid phases in the complex vector field holographic p-wave model. We find that in the probe limit, the p+ip phase and the p-wave phase are equally stable, hence the p and ip orders can be mixed with an arbitrary ratio to form more general p+λip phases, which are also equally stable with the p-wave and p+ip phases. As a result, the system possesses a degenerate thermal state in the superfluid region. We further study the case on considering the back-reaction on the metric, and we find that the degenerate ground states will be separated into p-wave and p+ip phases, and the p-wave phase is more stable. Finally, due to the different critical temperature of the zeroth order phase transitions from p-wave and p+ip phases to the normal phase, there is a temperature region where the p+ip phase exists but the p-wave phase does not. In this region we find the stable holographic p+ip phase for the first time. (orig.)

  17. High-velocity two-phase flow two-dimensional modeling

    International Nuclear Information System (INIS)

    Mathes, R.; Alemany, A.; Thilbault, J.P.

    1995-01-01

    The two-phase flow in the nozzle of a LMMHD (liquid metal magnetohydrodynamic) converter has been studied numerically and experimentally. A two-dimensional model for two-phase flow has been developed including the viscous terms (dragging and turbulence) and the interfacial mass, momentum and energy transfer between the phases. The numerical results were obtained by a finite volume method based on the SIMPLE algorithm. They have been verified by an experimental facility using air-water as a simulation pair and a phase Doppler particle analyzer for velocity and droplet size measurement. The numerical simulation of a lithium-cesium high-temperature pair showed that a nearly homogeneous and isothermal expansion of the two phases is possible with small pressure losses and high kinetic efficiencies. In the throat region a careful profiling is necessary to reduce the inertial effects on the liquid velocity field

  18. The effect of membrane-regulated actin polymerization on a two-phase flow model for cell motility

    KAUST Repository

    Kimpton, L. S.

    2014-07-23

    Two-phase flow models have been widely used to model cell motility and we have previously demonstrated that even the simplest, stripped-down, 1D model displays many observed features of cell motility [Kimpton, L.S., Whiteley, J.P., Waters, S.L., King, J.R. & Oliver, J.M. (2013) Multiple travelling-wave solutions in a minimal model for cell motility. Math. Med. Biol. 30, 241 - 272]. In this paper, we address a limitation of the previous model.We show that the two-phase flow framework can exhibit travelling-wave solutions with biologically plausible actin network profiles in two simple models that enforce polymerization or depolymerization of the actin network at the ends of the travelling, 1D strip of cytoplasm. © 2014 The authors 2014. Published by Oxford University Press on behalf of the Institute of Mathematics and its Applications. All rights reserved.

  19. Two-step nucleation of the g-phase in a Ti-45Al-18Nb alloy

    Energy Technology Data Exchange (ETDEWEB)

    Goyel, Sonalika [University of Florida, Gainesville; Rios, Orlando [ORNL; Kesler, Michael [University of Florida, Gainesville; Ebrahimi, Fereshteh [University of Florida, Gainesville

    2010-01-01

    Phase transformations in a high Nb TieAleNb alloy (Ti-45Al-18Nb at%) upon cooling were studied. This alloy solidifies as single b-phase, which upon cooling under equilibrium conditions, is expected to follow the b / b g / b g s / g s transformation path. The DTA analysis confirmed two transformation events as manifested by two peaks upon cooling. However, compositional and structural characterization of samples with different heat treatment schedules, including slow cooling (9 C/min), revealed that the s-phase did not form upon cooling. The two DTA peaks observed in the cooling cycle of the alloy are proven to be associated with the two-stage formation of the g-phase. Detailed microstructural evaluations showed that the g-phase nucleated in two discrete stages and exhibited two different morphologies. The absence of the s-phase is believed to be due to the lack of enough driving force at high temperatures. The aging of a fast cooled sample, yielding an equilibrated microstructure, substantiated the presence of the s-phase.

  20. Effects of phase transformation of steam-water relative permeabilities

    Energy Technology Data Exchange (ETDEWEB)

    Verma, A.K.

    1986-03-01

    A combined theoretical and experimental study of steam-water relative permeabilities (RPs) was carried out. First, an experimental study of two-phase concurrent flow of steam and water was conducted and a set of RP curves was obtained. These curves were compared with semi-empirical and experimental results obtained by other investigators for two-phase, two-component flow (oil/gas; gas/water; gas/oil). It was found that while the wetting phase RPs were in good agreement, RPs for the steam phase were considerably higher than the non-wetting phase RPs in two-component systems. This enhancement of steam RP is attributed to phase transformation effects at the pore level in flow channels. The effects of phase transformation were studied theoretically. This study indicates that there are two separate mechanisms by which phase transformation affects RP curves: (1) Phase transformation is converging-diverging flow channels can cause an enhancement of steam phase RP. In a channel dominated by steam a fraction of the flowing steam condenses upstream from the constriction, depositing its latent heat of condensation. This heat is conducted through the solid grains around the pore throat, and evaporation takes place downstream from it. Therefore, for a given bulk flow quality; a smaller fraction of steam actually flows through the throat segments. This pore-level effect manifests itself as relative permeability enhancement on a macroscopic level; and (2) phase transformation along the interface of a stagnant phase and the phase flowing around it controls the irreducible phase saturation. Therefore, the irreducible phase saturation in steam-water flow will depend, among other factors, on the boundary conditions of the flow.

  1. Ductile fracture of two-phase welds under 77K

    International Nuclear Information System (INIS)

    Yushchenko, K.A.; Voronin, S.A.; Pustovit, A.I.; Shavel', A.V.

    1984-01-01

    The effect of the type of welding and fillers on crack resistance of welded joints high-strength steel EhP810 and its various compounds with steels EhP666, 08Kh18N10T has been studied. For the welding of steel EhP810 with steels EhP810, EhP666, 08Kh18N10T electron-beam, automatic, argon tungsten arc with non-consumable electrode with various fillers, as well as argon metal-arc welding with consumable electrode, were used. It is shown, that for a joint, made by electron-beam welding, parameters σsub(u), Ksub(IcJ), KCV are higher than for a joint of a similar phase structure made using filler wire EhP659-VI. It is explained by the fact, that during electron-beam welding joint metal refining takes place, which removes gases. In welded joints of chP810 steel, having joints with austenitic structure, characteristic of crack resistance Ssub(c) increases by more than 0.2 mm in contrast to two-phase joints, which conventional yield strength at 77 K exceeds 1000 MPa. It is worth mentioning, that for other classes of steels formation of two-phase structure of joint increases welded joint resistance to brittle fracture. It is possible to obtain the required structure of joint with assigned level of resistance to brittle fracture by means of the use of different fillers, optimum and welding procedure, regulaing the part of the basic metal in joint content

  2. Coupling two-phase fluid flow with two-phase darcy flow in anisotropic porous media

    KAUST Repository

    Chen, J.

    2014-06-03

    This paper reports a numerical study of coupling two-phase fluid flow in a free fluid region with two-phase Darcy flow in a homogeneous and anisotropic porous medium region. The model consists of coupled Cahn-Hilliard and Navier-Stokes equations in the free fluid region and the two-phase Darcy law in the anisotropic porous medium region. A Robin-Robin domain decomposition method is used for the coupled Navier-Stokes and Darcy system with the generalized Beavers-Joseph-Saffman condition on the interface between the free flow and the porous media regions. Obtained results have shown the anisotropic properties effect on the velocity and pressure of the two-phase flow. 2014 Jie Chen et al.

  3. Coupling Two-Phase Fluid Flow with Two-Phase Darcy Flow in Anisotropic Porous Media

    Directory of Open Access Journals (Sweden)

    Jie Chen

    2014-06-01

    Full Text Available This paper reports a numerical study of coupling two-phase fluid flow in a free fluid region with two-phase Darcy flow in a homogeneous and anisotropic porous medium region. The model consists of coupled Cahn-Hilliard and Navier-Stokes equations in the free fluid region and the two-phase Darcy law in the anisotropic porous medium region. A Robin-Robin domain decomposition method is used for the coupled Navier-Stokes and Darcy system with the generalized Beavers-Joseph-Saffman condition on the interface between the free flow and the porous media regions. Obtained results have shown the anisotropic properties effect on the velocity and pressure of the two-phase flow.

  4. Stability of the high pressure phase Fe3S2 up to Earth's core pressures in the Fe-S-O and the Fe-S-Si systems

    Science.gov (United States)

    Zurkowski, C. C.; Chidester, B.; Davis, A.; Brauser, N.; Greenberg, E.; Prakapenka, V. B.; Campbell, A.

    2017-12-01

    Earth's core is comprised of an iron-nickel alloy that contains 5-15% of a light element component. The abundance and alloying capability of sulfur, silicon and oxygen in the bulk Earth make them important core alloy candidates; therefore, the high-pressure phase equilibria of the Fe-S-O and Fe-S-Si systems are relevant for understanding the possible chemistry of Earth's core. Previously, a Fe3S2 phase was recognized as a low-pressure intermediate phase in the Fe-FeS system that is stable from 14-21 GPa, but the structure of this phase has not been resolved. We report in-situ XRD and chemical analysis of recovered samples to further examine the stability and structure of Fe3S2 as it coexists with other phases in the Fe-S-O and Fe-S-Si systems. In situ high P-T synchrotron XRD experiments were conducted in the laser-heated diamond anvil cell to determine the equilibrium phases in Fe75S7O18 and Fe80S5Si15 compositions between 30 and 174 GPa and up to 3000 K. In the S,O-rich samples, an orthorhombic Fe3S2 phase coexists with hcp-Fe, Fe3S and FeO and undergoes two monoclinic distortions between 60 and 174 GPa. In the S,Si-rich samples, the orthorhombic Fe3S2 phase was observed up to 115 GPa. With increasing pressure, the Fe3S2 phase becomes stable to higher temperatures in both compositions, suggesting possible Fe3(S,O)2 or Fe3(S,Si)2 solid solutions. SEM analysis of a laser heated Fe75S7O18 sample recovered from 40 GPa and 1450 K confirms a Fe3(S,O)2 phase with O dissolved into the structure. Based on the current melting data in the Fe-S-O and Fe-S-Si systems, the Fe3(S,O)2 stability field intersects the solidus in the outer core and could be a possible liquidus phase in Fe,S,O-rich planetary cores, whereas Fe3S is the stable sulfide at outer core pressures in Fe,S,Si-rich systems.

  5. Phase relations in the metal-rich portions of the phase system Pt-Ir-Fe-S at 1000 degrees C and 1100 degrees C

    DEFF Research Database (Denmark)

    Makovicky, E.; Karup-Møller, Sven

    2000-01-01

    Phase relations in the S-poor portions of the dry condensed Pt-Ir-Fe-S system were determined at 1000 degrees and 1100 degreesC with a particular emphasis on delineation of the solid solubility fields of the Pt-Ir-Fe alloys. At both temperatures, a broad field of gamma (Ir,Fe,Pt) alloy coexists...... with gamma-(Pt,Fe), Pt3Fe and PtFe which dissolve respectively at least 5.1, 29.3 and 24.0 at.% Ir at 1100 degreesC (2.2, 23.6 and less than or equal to 17.2 at.% Ir at 1000 degreesC). Gaps between the nearly Ir-free Pt-Fe alloys gamma (Pt,Fe), Pt3Fe s.s., PtFe s.s. and gamma (Fe,Pt) were estimated as 20......-23 at.%, 40-42 at.% and 54.2-similar to 57 at.% Fe at 1100 degreesC (18-23, 39.5-42.5 and 59-62 at.% Fe at 1000 degreesC). The first gap agrees with data from natural phases by Cabri et ni. (1996). The Fe-rich sulphide melt dissolves only traces of Pt and Ir; Fe1-xS dissolves up to 5.8 at.% Ir at 1100...

  6. Huaier Aqueous Extract Induces Hepatocellular Carcinoma Cells Arrest in S Phase via JNK Signaling Pathway

    Directory of Open Access Journals (Sweden)

    Chengshuo Zhang

    2015-01-01

    Full Text Available Huaier aqueous extract, the main active constituent of Huaier proteoglycan, has antihepatocarcinoma activity in experimental and clinical settings. However, the potential and associated antihepatoma mechanisms of Huaier extract are not yet fully understood. Therefore, in this study, we aimed to elucidate the inhibitory proliferation effect of Huaier extract on apoptosis and cycle of HepG2 and Bel-7402 cells. Our data demonstrated that incubation with Huaier extract resulted in a marked decrease in cell viability dose-dependently. Flow cytometric analysis showed that a 48 h treatment of Huaier extract caused cell apoptosis. Typical apoptotic nucleus alterations were observed with fluorescence microscope after Hoechst staining. Immunoblot analysis further demonstrated that Huaier extract activated caspase 3 and PARP. Additionally, Huaier extract inhibited the activity of p-ERK, p-p38, and p-JNK in terms of MAPK. Furthermore, Huaier extract induced HCC cells arrest in S phase and decreased the cycle related protein expression of β-catenin and cyclin D1. Studies with JNK specific inhibitor, SP600125, showed that Huaier extract induced S phase arrest and decreased β-catenin and cyclin D1 expression via JNK signaling pathway. In conclusion, we verify that Huaier extract causes cell apoptosis and induces hepatocellular carcinoma cells arrest in S phase via JNK pathway, which advances our understanding on the molecular mechanisms of Huaier extract in hepatocarcinoma management.

  7. Photostability enhancement of InP/ZnS quantum dots enabled by In2O3 overcoating

    International Nuclear Information System (INIS)

    Jo, Jung-Ho; Kim, Jong-Hoon; Lee, Sun-Hyoung; Jang, Ho Seong; Jang, Dong Seon; Lee, Ju Chul; Park, Ko Un; Choi, Yoonyoung; Ha, Chunghun; Yang, Heesun

    2015-01-01

    Although the present-level quantum dots (QDs) exhibit excellent photoluminescent performance, their photostability under a prolonged photoexcitation stays doubtful and still unsatisfactory from an industrial perspective, since it determines the reliability of QD-incorporated devices such as QD-light-emitting diodes (QD-LEDs). In the present work, the overcoating of red-emitting InP/ZnS QDs with the oxide phase of In 2 O 3 is attempted to suppress the QD photooxidation, thus rendering them highly photostable. The efficacy of the oxide overlayer in substantially alleviating the QD photodegradation is verified through a comparative photostability test, where two colloidal solutions of bare versus In 2 O 3 -overcoated InP/ZnS (InP/ZnS@In 2 O 3 ) QDs are identically subjected to a continuous UV irradiation for an extended period of time. Furthermore, both InP/ZnS and InP/ZnS@In 2 O 3 QDs are packaged as color-converters with a blue LED chip, and the operational stability of the fabricated QD-LEDs is examined at a forward bias of 60 mA. Consistent with the results of UV irradiation experiment, InP/ZnS@In 2 O 3 QD-LED exhibits a superior device stability against a continual operation as compared with InP/ZnS one. - Graphical abstract: In 2 O 3 -overcoated InP/ZnS QD exhibited the superior photostability under continuous UV irradiation and LED operation for extended period of times compared to bare InP/ZnS one. - Highlights: • Red-emitting InP/ZnS QD is overcoated with the oxide phase of In 2 O 3 . • The efficacy of the oxide overlayer in substantially alleviating the QD photodegradation is demonstrated. • Compared to bare InP/ZnS QD In 2 O 3 -overcoated one exhibits the superior photostability against continuous photoexcitation

  8. Stability of Naturally Relevant Ternary Phases in the Cu–Sn–S system in Contact with an Aqueous Solution

    Directory of Open Access Journals (Sweden)

    Andrea Giaccherini

    2016-07-01

    Full Text Available A relevant research effort is devoted to the synthesis and characterization of phases belonging to the ternary system Cu–Sn–S, mainly for their possible applications in semiconductor technology. Among all ternary phases, kuramite, Cu3SnS4, mohite, Cu2SnS3, and Cu4Sn7S16 have attracted the highest interest. Numerous studies were carried out claiming for the description of new phases in the ternary compositional field. In this study, we revise the existing literature on this ternary system, with a special focus on the phases stable in a temperature range at 25 °C. The only two ternary phases observed in nature are mohite and kuramite. Their occurrence is described as very rare. A numerical modelling of the stable solid phases in contact with a water solution was underwent to define stability relationships of the relevant phases of the system. The numerical modelling of the Eh-pH diagrams was carried out through the phreeqc software with the lnll.dat thermodynamic database. Owing to the complexity of this task, the subsystems Cu–O–H, Sn–O–H, Cu–S–O–H and Sn–S–O–H were firstly considered. The first Pourbaix diagram for the two naturally relevant ternary phases is then proposed.

  9. Phase field study of interfacial diffusion-driven spheroidization in a composite comprized of two mutually insoluble phases

    Energy Technology Data Exchange (ETDEWEB)

    Tian, Liang [Ames Laboratory; Russell, Alan [Ames Laboratory

    2014-03-27

    The phase field approach is a powerful computational technique to simulate morphological and microstructural evolution at the mesoscale. Spheroidization is a frequently observed morphological change of mesoscale heterogeneous structures during annealing. In this study, we used the diffuse interface phase field method to investigate the interfacial diffusion-driven spheroidization of cylindrical rod structures in a composite comprised of two mutually insoluble phases in a two-dimensional case. Perturbation of rod radius along a cylinder's axis has long been known to cause the necessary chemical potential gradient that drives spheroidization of the rod by Lord Rayleigh's instability theory. This theory indicates that a radius perturbation wavelength larger than the initial rod circumference would lead to cylindrical spheroidization. We investigated the effect of perturbation wavelength, interfacial energy, volume diffusion, phase composition, and interfacial percentage on the kinetics of spheroidization. The results match well with both the Rayleigh's instability criterion and experimental observations.

  10. Relations between temperature coefficients of permittivity and elastic compliances in PZT ceramics near the morphotropic phase boundary.

    Science.gov (United States)

    Boudys, M

    1991-01-01

    Variations of temperature coefficients of permittivity epsilon(33)(T), elastic compliances at constant electric fields s(11)(E), and constant polarization s(11)(P) with a Zr/Ti ratio of Pb(Zr(x)Ti(1-x))O(3) and Pb[(Sb(1/3)Mn(2/3))(0.05)Zr(x)Ti (0.95-x)]O(3) solid solutions, were investigated. Relations between temperature coefficients of epsilon(33)(T ), S(11)(E), and S(11) (P) were theoretically derived; a discrepancy was found between theoretical relations and experimental results. On the basis of the observed discrepancy, it is proposed that some extrinsic effects arising from the motion of interphase boundaries between the tetragonal and the rhombohedral phases which exist in grains contribute to values of both elastic compliances.

  11. T-p phase diagrams and the barocaloric effect in materials with successive phase transitions

    Science.gov (United States)

    Gorev, M. V.; Bogdanov, E. V.; Flerov, I. N.

    2017-09-01

    An analysis of the extensive and intensive barocaloric effect (BCE) at successive structural phase transitions in some complex fluorides and oxyfluorides was performed. The high sensitivity of these compounds to a change in the chemical pressure allows one to vary the succession and parameters of the transformations (temperature, entropy, baric coefficient) over a wide range and obtain optimal values of the BCE. A comparison of different types of schematic T-p phase diagrams with the complicated T( p) dependences observed experimentally shows that in some ranges of temperature and pressure the BCE in compounds undergoing successive transformations can be increased due to a summation of caloric effects associated with distinct phase transitions. The maximum values of the extensive and intensive BCE in complex fluorides and oxyfluorides can be realized at rather low pressure (0.1-0.3 GPa). In a narrow temperature range around the triple points conversion from conventional BCE to inverse BCE is observed, which is followed by a gigantic change of both \\vertΔ S_BCE\\vert and \\vertΔ T_AD\\vert .

  12. Two-phase flow

    International Nuclear Information System (INIS)

    Olive, J.

    1990-01-01

    The design, operation and safety of nuclear components requires increasingly accurate knowledge of two-phase flows. This knowledge is also necessary for some studies related to electricity applications. The author presents some concrete examples showing the range of problems and the complexity of the phenomena involved in these types of flows. Then, the basic principles of their numerical modelling are explained, as well as the new tendency to use increasingly local and refined models. The newest computer codes developed at EDF are briefly presented. Experimental studies dealing with twophase flow are also referred to, and their connections to numerical modelling are explained. Emphasis is placed on the major efforts devoted to the development of new test rigs and instrumentation [fr

  13. Two-phase titration of cerium(III) by permanganate

    International Nuclear Information System (INIS)

    Lazarev, A.I.; Lazareva, V.I.; Gerko, V.V.

    1987-01-01

    This paper presents a method for the two-phase titrimetric determination of cerium(III) with permanganate which does not require an expenditure of sugar and preliminary removal of chlorides and nitrates. The interaction of cerium(III) with permanganate at room temperature was studied as a function of the pH, the concentration of pyrophosphate, tetraphenylphosphonium (TPP), permanganate, and extraneous compounds, the rate of titration, and the time of stay of the solution in air before titration. The investigations were conducted according to the following methodology: water, solution of cerium(III) pyrophosphate, and TPP were introduced into an Erlenmeyer flask with a side branch near the bottom for clearer observation of the color of the chloroform phase. The authors established the given pH value, poured the water into a volume of 50 ml, and added chloroform. The result was titrated with permanganate solutions of various concentrations until a violet color appeared in the chloroform phase

  14. Electrical Capacitance Probe Characterization in Vertical Annular Two-Phase Flow

    Directory of Open Access Journals (Sweden)

    Grazia Monni

    2013-01-01

    Full Text Available The paper presents the experimental analysis and the characterization of an electrical capacitance probe (ECP that has been developed at the SIET Italian Company, for the measurement of two-phase flow parameters during the experimental simulation of nuclear accidents, as LOCA. The ECP is used to investigate a vertical air/water flow, characterized by void fraction higher than 95%, with mass flow rates ranging from 0.094 to 0.15 kg/s for air and from 0.002 to 0.021 kg/s for water, corresponding to an annular flow pattern. From the ECP signals, the electrode shape functions (i.e., the signals as a function of electrode distances in single- and two-phase flows are obtained. The dependence of the signal on the void fraction is derived and the liquid film thickness and the phase’s velocity are evaluated by means of rather simple models. The experimental analysis allows one to characterize the ECP, showing the advantages and the drawbacks of this technique for the two-phase flow characterization at high void fraction.

  15. Environment-related properties of polyhydroxylated dibenzo-p-dioxins

    International Nuclear Information System (INIS)

    Shi, Jia-Qi; Qu, Rui-juan; Flamm, Alison; Liu, Hong-Xia; Xu, Ying; Wang, Zun-Yao

    2012-01-01

    Polyhydroxylated dibenzo-p-dioxins (PHODDs) are important metabolic and synthetic products of polychlorinated dibenzo-p-dioxins (PCDDs). Two types of hydrogen bonds exist in PHODD molecules: one between a hydroxyl group (HO) and an oxygen atom of the ether bond, and the other between two ortho hydroxyls of a benzene ring. By fully optimized calculation with density functional theory (DFT), their bond energies were ascertained to be approximately 9–14 kJ/mol and 15–19 kJ/mol respectively by the comparison of standard Gibbs energy of formation (Δ f G θ ) between different molecules, which was experimentally verified. The two types of hydrogen bonds affect the hydrophilicity and stability of the molecules. The torsional potential of hydroxyls and the orientation making the congener most stable were obtained. The octanol-water partition coefficients (logK ow s) were calculated based on the group contribution method, and the standard state entropy (S θ ), standard enthalpy (Δ f H θ ) of formation and Δ f G θ were obtained from the combination of DFT calculation and isodesmic reaction for the stable PHODD congeners. The number and position of hydroxyl substitution (N PHOS ) were employed as descriptors to establish quantitative structure–property relationship (QSPR) models. Although the hydrophilicity of PHODDs increases with the number of hydroxyl groups, it is impaired by the intramolecular hydrogen bonds. The logK ow s of PHODDs are much smaller than those of PCDDs, and the variation trend with the number of substituents is different. In addition, the relative stability order of PHODD congeners was theoretically proposed, which is quite different from that of PCDDs. Considering the ionization in water, first-order ionization constants of PHODDs were calculated according to the results of SMD method of Self-Consistent Reaction Field Theory (SCRF), and they were influenced by the hydrogen bonds. - Highlights: ► Hydroxyl torsional potential and hydrogen

  16. Obesity-stimulated aldosterone release is not related to an S1P-dependent mechanism.

    Science.gov (United States)

    Werth, Stephan; Müller-Fielitz, Helge; Raasch, Walter

    2017-12-01

    Aldosterone has been identified as an important factor in obesity-associated hypertension. Here, we investigated whether sphingosine-1-phosphate (S1P), which has previously been linked to obesity, increases aldosterone release. S1P-induced aldosterone release was determined in NCI H295R cells in the presence of S1P receptor (S1PR) antagonists. In vivo release of S1P (100-300 µg/kg bw ) was investigated in pithed, lean Sprague Dawley (SD) rats, diet-obese spontaneous hypertensive rats (SHRs), as well as in lean or obese Zucker rats. Aldosterone secretion was increased in NCI H295R cells by S1P, the selective S1PR1 agonist SEW2871 and the selective S1PR2 antagonist JTE013. Treatment with the S1PR1 antagonist W146 or fingolimod and the S1PR1/3 antagonist VPbib2319 decreased baseline and/or S1P-stimulated aldosterone release. Compared to saline-treated SD rats, plasma aldosterone increased by ~50 pg/mL after infusing S1P. Baseline levels of S1P and aldosterone were higher in obese than in lean SHRs. Adrenal S1PR expression did not differ between chow- or CD-fed rats that had the highest S1PR1 and lowest S1PR4 levels. S1P induced a short-lasting increase in plasma aldosterone in obese, but not in lean SHRs. However, 2-ANOVA did not demonstrate any difference between lean and obese rats. S1P-induced aldosterone release was also similar between obese and lean Zucker rats. We conclude that S1P is a local regulator of aldosterone production. S1PR1 agonism induces an increase in aldosterone secretion, while stimulating adrenal S1PR2 receptor suppresses aldosterone production. A significant role of S1P in influencing aldosterone secretion in states of obesity seems unlikely. © 2017 Society for Endocrinology.

  17. Non-overlapped P- and S-wave Poynting vectors and its solution on Grid Method

    KAUST Repository

    Lu, Yong Ming; Liu, Qiancheng

    2017-01-01

    Poynting vector represents the local directional energy flux density of seismic waves in geophysics. It is widely used in elastic reverse time migration (RTM) to analyze source illumination, suppress low-wavenumber noise, correct for image polarity and extract angle-domain common imaging gather (ADCIG). However, the P and S waves are mixed together during wavefield propagation such that the P and S energy fluxes are not clean everywhere, especially at the overlapped points. In this paper, we use a modified elastic wave equation in which the P and S vector wavefields are naturally separated. Then, we develop an efficient method to evaluate the separable P and S poynting vectors, respectively, based on the view that the group velocity and phase velocity have the same direction in isotropic elastic media. We furthermore formulate our method using an unstructured mesh based modeling method named the grid method. Finally, we verify our method using two numerical examples.

  18. Non-overlapped P- and S-wave Poynting vectors and its solution on Grid Method

    KAUST Repository

    Lu, Yong Ming

    2017-12-12

    Poynting vector represents the local directional energy flux density of seismic waves in geophysics. It is widely used in elastic reverse time migration (RTM) to analyze source illumination, suppress low-wavenumber noise, correct for image polarity and extract angle-domain common imaging gather (ADCIG). However, the P and S waves are mixed together during wavefield propagation such that the P and S energy fluxes are not clean everywhere, especially at the overlapped points. In this paper, we use a modified elastic wave equation in which the P and S vector wavefields are naturally separated. Then, we develop an efficient method to evaluate the separable P and S poynting vectors, respectively, based on the view that the group velocity and phase velocity have the same direction in isotropic elastic media. We furthermore formulate our method using an unstructured mesh based modeling method named the grid method. Finally, we verify our method using two numerical examples.

  19. Determination of the phase $\\phi_{s}$ at LHCb

    CERN Document Server

    Batozskaya, Varvara

    2018-01-01

    The determination of the mixing-induced $C\\!P$-violating phase $\\phi_{s}$ in the $B^{0}_{s}-\\bar{B}^{0}_{s}$ system is one of the key goals of the LHCb experiment. Using several $B^{0}_{s}$ decay modes it has been measured by the LHCb collaboration exploiting the Run~I data set. The first observation of the $B^{0}_{s}\\to\\eta_{c}\\phi$ and $B^{0}_{s}\\to\\eta_{c}\\pi^{+}\\pi^{-}$ decay modes which can be used to measure $\\phi_{s}$ with Run~II data is presented.

  20. Selectivity of calixarene-bonded silica-phases in HPLC: description of special characteristics with a multiple term linear equation at two different pH-values.

    Science.gov (United States)

    Schneider, Christian; Meyer, Rüdiger; Jira, Thomas

    2008-09-01

    Six different calixarene-bonded phases were characterized by analyzing 36 and 26 solutes at pH 3 and 7, respectively. Dolan and Snyder's multiple term linear equation was used to correlate retention factors k' to parameters of the solutes and columns. The column parameters have been related to molecular properties of the stationary phases and new suggestions were made for the interpretation of steric selectivity. Ionic and polar interactions have been found dependent on pH value, while steric interactions are less dependent and hydrophobic interactions remain unchanged. Distinct differences of the supported interactions were confirmed between the calixarene-bonded and the common alkyl-bonded silicas. By use of the parameters, values of k' can be estimated with an average deviation of 2.50 and 7.92% at low and neutral pH-value, respectively.

  1. Single and two-phase similarity analysis of a reduced-scale natural convection loop relative to a full-scale prototype

    International Nuclear Information System (INIS)

    Botelho, David A.; Faccini, Jose L.H.

    2002-01-01

    The main topic in this paper is a new device being considered to improve nuclear reactor safety employing the natural circulation. A scaled experiment used to demonstrate the performance of the device is also described. We also applied a similarity analysis method for single and two-phase natural convection loop flow to the IEN CCN experiment and to an APEX like experiment to verify the degree of similarity relative to a full-scale prototype like the AP600. Most of the CCN similarity numbers that represent important single and two-phase similarity conditions are comparable to the APEX like loop non-dimensional numbers calculated employing the same methodology. Despite the much smaller geometric, pressure, and power scales, we conclude that the IEN CCN has single and two-phase natural circulation similarity numbers that represent fairly well the full-scale prototype. even lacking most complementary primary and safety systems, this IEN circuit provided a much valid experience to develop human, experimental, and analytical resources, besides its utilization as a training tool. (author)

  2. Record mobility in transparent p-type tin monoxide films and devices by phase engineering

    KAUST Repository

    Caraveo-Frescas, Jesus Alfonso

    2013-06-25

    Here, we report the fabrication of nanoscale (15 nm) fully transparent p-type SnO thin film transistors (TFT) at temperatures as low as 180 C with record device performance. Specifically, by carefully controlling the process conditions, we have developed SnO thin films with a Hall mobility of 18.71 cm2 V-1 s-1 and fabricated TFT devices with a linear field-effect mobility of 6.75 cm2 V-1 s -1 and 5.87 cm2 V-1 s-1 on transparent rigid and translucent flexible substrates, respectively. These values of mobility are the highest reported to date for any p-type oxide processed at this low temperature. We further demonstrate that this high mobility is realized by careful phase engineering. Specifically, we show that phase-pure SnO is not necessarily the highest mobility phase; instead, well-controlled amounts of residual metallic tin are shown to substantially increase the hole mobility. A detailed phase stability map for physical vapor deposition of nanoscale SnO is constructed for the first time for this p-type oxide. © 2013 American Chemical Society.

  3. Using brain potentials to understand prism adaptation: the error-related negativity and the P300

    Directory of Open Access Journals (Sweden)

    Stephane Joseph Maclean

    2015-06-01

    Full Text Available Prism adaptation (PA is both a perceptual-motor learning task as well as a promising rehabilitation tool for visuo-spatial neglect (VSN – a spatial attention disorder often experienced after stroke resulting in slowed and/or inaccurate motor responses to contralesional targets. During PA, individuals are exposed to prism-induced shifts of the visual-field while performing a visuo-guided reaching task. After adaptation, with goggles removed, visuo-motor responding is shifted to the opposite direction of that initially induced by the prisms. This visuo-motor aftereffect has been used to study visuo-motor learning and adaptation and has been applied clinically to reduce VSN severity by improving motor responding to stimuli in contralesional (usually left-sided space. In order to optimize PA’s use for VSN patients, it is important to elucidate the neural and cognitive processes that alter visuomotor function during PA. In the present study, healthy young adults underwent PA while event-related potentials (ERPs were recorded at the termination of each reach (screen-touch, then binned according to accuracy (hit vs. miss and phase of exposure block (early, middle, late. Results show that two ERP components were evoked by screen-touch: an early error-related negativity (ERN, and a P300. The ERN was consistently evoked on miss trials during adaptation, while the P300 amplitude was largest during the early phase of adaptation for both hit and miss trials. This study provides evidence of two neural signals sensitive to visual feedback during PA that may sub-serve changes in visuomotor responding. Prior ERP research suggests that the ERN reflects an error processing system in medial-frontal cortex, while the P300 is suggested to reflect a system for context updating and learning. Future research is needed to elucidate the role of these ERP components in improving visuomotor responses among individuals with VSN.

  4. Phase composition and in vitro bioactivity of porous implants made of bioactive glass S53P4.

    Science.gov (United States)

    Fagerlund, S; Massera, J; Moritz, N; Hupa, L; Hupa, M

    2012-07-01

    This work studied the influence of sintering temperature on the phase composition, compression strength and in vitro properties of implants made of bioactive glass S53P4. The implants were sintered within the temperature range 600-1000°C. Over the whole temperature range studied, consolidation took place mainly via viscous flow sintering, even though there was partial surface crystallization. The mechanical strength of the implants was low but increased with the sintering temperature, from 0.7 MPa at 635°C to 10 MPa at 1000°C. Changes in the composition of simulated body fluid (SBF), the immersion solution, were evaluated by pH measurements and ion analysis using inductively coupled plasma optical emission spectrometry. The development of a calcium phosphate layer on the implant surfaces was verified using scanning electron microscopy-electron-dispersive X-ray analysis. When immersed in SBF, a calcium phosphate layer formed on all the samples, but the structure of this layer was affected by the surface crystalline phases. Hydroxyapatite formed more readily on amorphous and partially crystalline implants containing both primary Na(2)O·CaO·2SiO(2) and secondary Na(2)Ca(4)(PO(4))(2)SiO(4) crystals than on implants containing only primary crystals. Copyright © 2012 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

  5. Measurements of liquid-phase turbulence in gas–liquid two-phase flows using particle image velocimetry

    International Nuclear Information System (INIS)

    Zhou, Xinquan; Doup, Benjamin; Sun, Xiaodong

    2013-01-01

    Liquid-phase turbulence measurements were performed in an air–water two-phase flow loop with a circular test section of 50 mm inner diameter using a particle image velocimetry (PIV) system. An optical phase separation method-–planar laser-induced fluorescence (PLIF) technique—which uses fluorescent particles and an optical filtration technique, was employed to separate the signals of the fluorescent seeding particles from those due to bubbles and other noises. An image pre-processing scheme was applied to the raw PIV images to remove the noise residuals that are not removed by the PLIF technique. In addition, four-sensor conductivity probes were adopted to measure the radial distribution of the void fraction. Two benchmark tests were performed: the first was a comparison of the PIV measurement results with those of similar flow conditions using thermal anemometry from previous studies; the second quantitatively compared the superficial liquid velocities calculated from the local liquid velocity and void fraction measurements with the global liquid flow rate measurements. The differences of the superficial liquid velocity obtained from the two measurements were bounded within ±7% for single-phase flows and two-phase bubbly flows with the area-average void fraction up to 18%. Furthermore, a preliminary uncertainty analysis was conducted to investigate the accuracy of the two-phase PIV measurements. The systematic uncertainties due to the circular pipe curvature effects, bubble surface reflection effects and other potential uncertainty sources of the PIV measurements were discussed. The purpose of this work is to facilitate the development of a measurement technique (PIV-PLIF) combined with image pre-processing for the liquid-phase turbulence in gas–liquid two-phase flows of relatively high void fractions. The high-resolution data set can be used to more thoroughly understand two-phase flow behavior, develop liquid-phase turbulence models, and assess high

  6. Two-phase flux simulations by robots

    International Nuclear Information System (INIS)

    Barrera, F.D.

    1997-01-01

    Two-Phase flow systems are studied following the statistical formulation, which takes into account the bubble population balances. This is done by means of automata simulation. Geometrical automata are associated to the dispersed phase, and are represented by discs on the plane, resembling bubbles moving in a fluid environment. Following pre-determined rules, the automata evolve, and useful statistical information about their interaction is obtained. This information is applied in the present work to study the mechanisms that induce bubble coalescence. Models for one and two sized automata are presented. It was found that in the case of the model for one size, the probability of interaction among bubbles and the pair correlation function depends not only on the void fraction, but also on the number of elements of the dispersed phase. A correlation for the collision probability between two bubbles is obtained, and this result was extended to the pair correlation function. For the case of systems with two characteristic sizes, a model was formulated for analyzing the interaction among bubbles of the two groups. The interaction of bubbles for one and two sized systems were related by a symmetry factor, which shows the dependence of the interaction among bubbles with the size distribution. By means of the automata simulation, the phenomena of bubble confinement and screening were characterized. It was found that the first phenomenon is stronger in systems with greater distance among bubbles, and that the second effect increases with void fraction and bubble number. (author)

  7. Ground-state phase diagram of an (S, S') = (1, 2) spin-alternating chain with competing single-ion anisotropies

    International Nuclear Information System (INIS)

    Tonegawa, T; Okamoto, K; Sakai, T; Kaburagi, M

    2009-01-01

    Employing various numerical methods, we determine the ground-state phase diagram of an (S, S') = (1, 2) spin-alternating chain with antiferromagnetic nearest-neighboring exchange interactions and uniaxial single-ion anisotropies. The resulting phase diagram consists of eight kinds of phases including two phases which accompany the spontaneous breaking of the translational symmetry and a ferrimagnetic phase in which the ground-state magnetization varies continuously with the uniaxial single-ion anisotropy constants for the S=1 and S =2 spins. The appearance of these three phases is attributed to the competition between the uniaxial single-ion anisotropies of both spins.

  8. Two-phase flow characteristics in BWRs

    International Nuclear Information System (INIS)

    Katono, Kenichi; Aoyama, Goro; Nagayoshi, Takuji; Yasuda, Kenichi; Nishida, Koji

    2014-01-01

    Reliable prediction of two-phase flow characteristics is important for safety and economy improvements of BWR plants. We have been developing two-phase flow measurement tools and techniques for BWR thermal hydraulic conditions, such as a 3D time-averaged X-ray CT system, an ultrasonic liquid film sensor and a wire-mesh sensor. We applied the developed items in experiments using the multi-purpose steam-water test facility known as HUSTLE, which can simulate two-phase thermal-hydraulic conditions in a BWR reactor pressure vessel, and we constructed a detailed instrumentation database. We validated a 3D two-phase flow simulator using the database and developed the reactor internal two-phase flow analysis system. (author)

  9. Prognostic value of lymphoma-specific S-phase fraction compared with that of other cell proliferation markers

    Energy Technology Data Exchange (ETDEWEB)

    Holte, H.; Kvaloey, S. [Dept. of Oncology, Univ. of Oslo (Norway); Suo Zhenhe; Langholm, R. [Dept. of Pathology, Univ. of Oslo (Norway); Smeland, E.B. [Dept. of Immunology, Univ. of Oslo (Norway); Stokke, T. [Dept. of Biophysics, Univ. of Oslo (Norway)

    1999-11-01

    The proliferation-associated antigens Ki67 (immunohistochemistry) and proliferative cell nuclear antigen (PCNA) (immunohistochemistry and immunoblotting) were analysed together with DNA synthesis ({sup 3}H-thymidine incorporation) and cell-cycle distribution (tumour-specific S-phase fraction determined by flow cytometry) in lymph node suspensions from 63 patients with newly diagnosed B-Cell non-Hodgkin`s lymphomas. Details of clinical parameters, treatment and patient outcome were available for all patients, and retrospectively analysed. Of the proliferation-associated parameters, only high S-phase fraction (p < 0.00001) and high PCNA expression by immunoblotting (p=0.012) were predictive of a poor prognosis. Of the conventional parameters, high-grade malignancy, high International Prognostic Index (IPI) score, bulky disease and presence of B symptoms predicted a patient for poor survival. High S-phase fraction was predictive of a short survival for the low-grade lymphomas analyses separately (p < 0.00001), as well as for patients treated with an Adriamycin- and a non-Adriamycin-containing regimen (p < 0.005 for both groups). In a multivariate analysis, S-phase fraction (p=0.00006), IPI score (p=0.015) and B symptoms (p=0.017) had independent prognostic values, but not histological grade. (orig.)

  10. Two-phase aqueous micellar systems: an alternative method for protein purification

    Directory of Open Access Journals (Sweden)

    Rangel-Yagui C. O.

    2004-01-01

    Full Text Available Two-phase aqueous micellar systems can be exploited in separation science for the extraction/purification of desired biomolecules. This article reviews recent experimental and theoretical work by Blankschtein and co-workers on the use of two-phase aqueous micellar systems for the separation of hydrophilic proteins. The experimental partitioning behavior of the enzyme glucose-6-phosphate dehydrogenase (G6PD in two-phase aqueous micellar systems is also reviewed and new results are presented. Specifically, we discuss very recent work on the purification of G6PD using: i a two-phase aqueous micellar system composed of the nonionic surfactant n-decyl tetra(ethylene oxide (C10E4, and (ii a two-phase aqueous mixed micellar system composed of C10E4 and the cationic surfactant decyltrimethylammonium bromide (C10TAB. Our results indicate that the two-phase aqueous mixed (C10E4/C10TAB micellar system can improve significantly the partitioning behavior of G6PD relative to that observed in the two-phase aqueous C10E4 micellar system.

  11. Enhancement of the photovoltaic performance in P3HT: PbS hybrid solar cells using small size PbS quantum dots

    Energy Technology Data Exchange (ETDEWEB)

    Firdaus, Yuliar; Van der Auweraer, Mark, E-mail: mark.vanderauweraer@chem.kuleuven.be [Laboratory of Photochemistry and Spectroscopy, Division of Molecular Imaging and Photonics, Chemistry Department, KULeuven, Celestijnenlaan 200F, 2404, B-3001 Leuven (Belgium); Vandenplas, Erwin; Gehlhaar, Robert; Cheyns, David [Imec vzw, Kapeldreef 75, B-3001 Leuven (Belgium); Justo, Yolanda; Hens, Zeger [Physical Chemistry Laboratory, Ghent University, Krijgslaan 281-S3, 9000 Gent (Belgium)

    2014-09-07

    Different approaches of surface modification of the quantum dots (QDs), namely, solution-phase (octylamine, octanethiol) and post-deposition (acetic acid, 1,4-benzenedithiol) ligand exchange were used in the fabrication of hybrid bulk heterojunction solar cell containing poly (3-hexylthiophene) (P3HT) and small (2.4 nm) PbS QDs. We show that replacing oleic acid by shorter chain ligands improves the figures of merit of the solar cells. This can possibly be attributed to a combination of a reduced thickness of the barrier for electron transfer and an optimized phase separation. The best results were obtained for post-deposition ligand exchange by 1,4-benzenedithiol, which improves the power conversion efficiency of solar cells based on a bulk heterojunction of lead sulfide (PbS) QDs and P3HT up to two orders of magnitude over previously reported hybrid cells based on a bulk heterojunction of P3HT:PbS QDs, where the QDs are capped by acetic acid ligands. The optimal performance was obtained for solar cells with 69 wt. % PbS QDs. Besides the ligand effects, the improvement was attributed to the formation of an energetically favorable bulk heterojunction with P3HT, when small size (2.4 nm) PbS QDs were used. Dark current density-voltage (J-V) measurements carried out on the device provided insight into the working mechanism: the comparison between the dark J-V characteristics of the bench mark system P3HT:PCBM and the P3HT:PbS blends allows us to conclude that a larger leakage current and a more efficient recombination are the major factors responsible for the larger losses in the hybrid system.

  12. Enhancement of the photovoltaic performance in P3HT: PbS hybrid solar cells using small size PbS quantum dots

    International Nuclear Information System (INIS)

    Firdaus, Yuliar; Van der Auweraer, Mark; Vandenplas, Erwin; Gehlhaar, Robert; Cheyns, David; Justo, Yolanda; Hens, Zeger

    2014-01-01

    Different approaches of surface modification of the quantum dots (QDs), namely, solution-phase (octylamine, octanethiol) and post-deposition (acetic acid, 1,4-benzenedithiol) ligand exchange were used in the fabrication of hybrid bulk heterojunction solar cell containing poly (3-hexylthiophene) (P3HT) and small (2.4 nm) PbS QDs. We show that replacing oleic acid by shorter chain ligands improves the figures of merit of the solar cells. This can possibly be attributed to a combination of a reduced thickness of the barrier for electron transfer and an optimized phase separation. The best results were obtained for post-deposition ligand exchange by 1,4-benzenedithiol, which improves the power conversion efficiency of solar cells based on a bulk heterojunction of lead sulfide (PbS) QDs and P3HT up to two orders of magnitude over previously reported hybrid cells based on a bulk heterojunction of P3HT:PbS QDs, where the QDs are capped by acetic acid ligands. The optimal performance was obtained for solar cells with 69 wt. % PbS QDs. Besides the ligand effects, the improvement was attributed to the formation of an energetically favorable bulk heterojunction with P3HT, when small size (2.4 nm) PbS QDs were used. Dark current density-voltage (J-V) measurements carried out on the device provided insight into the working mechanism: the comparison between the dark J-V characteristics of the bench mark system P3HT:PCBM and the P3HT:PbS blends allows us to conclude that a larger leakage current and a more efficient recombination are the major factors responsible for the larger losses in the hybrid system

  13. System identification on two-phase flow stability

    International Nuclear Information System (INIS)

    Wu Shaorong; Zhang Youjie; Wang Dazhong; Bo Jinghai; Wang Fei

    1996-01-01

    The theoretical principle, experimental method and results of interrelation analysis identification for the instability of two-phase flow are described. A completely new concept of test technology and method on two-phase flow stability was developed by using he theory of information science on system stability and system identification for two-phase flow stability in thermo-physics field. Application of this method would make it possible to identify instability boundary of two-phase flow under stable operation conditions of two-phase flow system. The experiment was carried out on the thermohydraulic test system HRTL-5. Using reverse repeated pseudo-random sequences of heating power as input signal sources and flow rate as response function in the test, the two-phase flow stability and stability margin of the natural circulation system are investigated. The effectiveness and feasibility of identifying two-phase flow stability by using this system identification method were experimentally demonstrated. Basic data required for mathematics modeling of two-phase flow and analysis of two-phase flow stability were obtained, which are useful for analyzing, monitoring of the system operation condition, and forecasting of two-phase flow stability in engineering system

  14. Quasistatic analysis on configuration of two-phase flow in Y-shaped tubes

    KAUST Repository

    Zhong, Hua

    2014-12-01

    We investigate the two-phase flow in a horizontally placed Y-shaped tube with different Young\\'s angle and width in each branch. By using a quasistatic approach, we can determine the specific contact position and the equilibrium contact angle of fluid in each branch based on the minimization problem of the free energy of the system. The wettability condition and the width of the two branches play important roles in the distribution of fluid in each branch. We also consider the effect of gravity. Some fluid in the upper branch will be pulled down due to the competition of the surface energy and the gravitational energy. The result provides some insights on the theory of two-phase flow in porous media. In particular, it highlights that the inhomogeneous wettability distribution affects the direction of the fluid penetrating a given porous medium domain. It also sheds light on the current debate whether relative permeability may be considered as a full tensor rather than a scalar.

  15. Two-phase air-water stratified flow measurement using ultrasonic techniques

    International Nuclear Information System (INIS)

    Fan, Shiwei; Yan, Tinghu; Yeung, Hoi

    2014-01-01

    In this paper, a time resolved ultrasound system was developed for investigating two-phase air-water stratified flow. The hardware of the system includes a pulsed wave transducer, a pulser/receiver, and a digital oscilloscope. The time domain cross correlation method is used to calculate the velocity profile along ultrasonic beam. The system is able to provide velocities with spatial resolution of around 1mm and the temporal resolution of 200μs. Experiments were carried out on single phase water flow and two-phase air-water stratified flow. For single phase water flow, the flow rates from ultrasound system were compared with those from electromagnetic flow (EM) meter, which showed good agreement. Then, the experiments were conducted on two-phase air-water stratified flow and the results were given. Compared with liquid height measurement from conductance probe, it indicated that the measured velocities were explainable

  16. Angular distribution for the elastic scattering of electrons from Ar+(3s23p52P) above the first inelastic threshold

    International Nuclear Information System (INIS)

    Brotton, S.J.; McKenna, P.; Gribakin, G.; Williams, I.D.

    2002-01-01

    The measured angular differential cross section (DCS) for the elastic scattering of electrons from Ar + (3s 2 3p 5 2 P) at the collision energy of 16 eV is presented. By solving the Hartree-Fock equations, we calculate the corresponding theoretical DCS including the coupling between the orbital angular momenta and spin of the incident electron and those of the target ion and also relaxation effects. Since the collision energy is above one inelastic threshold for the transition 3s 2 3p 5 2 P-3s3p 6 2 S, we consider the effects on the DCS of inelastic absorption processes and elastic resonances. The measurements deviate significantly from the Rutherford cross section over the full angular range observed, especially in the region of a deep minimum centered at approximately 75 deg. Our theory and an uncoupled, unrelaxed method using a local, spherically symmetric potential by Manson [Phys. Rev. 182, 97 (1969)] both reproduce the overall shape of the measured DCS, although the coupled Hartree-Fock approach describes the depth of the minimum more accurately. The minimum is shallower in the present theory owing to our lower average value for the d-wave non-Coulomb phase shift σ 2 , which is due to the high sensitivity of σ 2 to the different scattering potentials used in the two models. The present measurements and calculations therefore show the importance of including coupling and relaxation effects when accurately modeling electron-ion collisions. The phase shifts obtained by fitting to the measurements are compared with the values of Manson and the present method

  17. Analog phase lock between two lasers at LISA power levels

    International Nuclear Information System (INIS)

    Diekmann, Christian; Steier, Frank; Sheard, Benjamin; Heinzel, Gerhard; Danzmann, Karsten

    2009-01-01

    This paper presents the implementation of an analog optical phase-locked-loop with an offset frequency of about 20MHz between two lasers, where the detected light powers were of the order of 31 pW and 200 μW. The goal of this setup was the design and characterization of a photodiode transimpedance amplifier for application in LISA. By application of a transimpedance amplifier designed to have low noise and low power consumption, the phase noise between the two lasers was a factor of two above the shot noise limit down to 60mHz. The achievable phase sensitivity depends ultimately on the available power of the highly attenuated master laser and on the input current noise of the transimpedance amplifier of the photodetector. The limiting noise source below 60mHz was the analog phase measurement system that was used in this experiment. A digital phase measurement system that is currently under development at the AEI will be used in the near future. Its application should improve the sensitivity.

  18. Analog phase lock between two lasers at LISA power levels

    Energy Technology Data Exchange (ETDEWEB)

    Diekmann, Christian; Steier, Frank; Sheard, Benjamin; Heinzel, Gerhard; Danzmann, Karsten, E-mail: Christian.Diekmann@aei.mpg.d [Max-Planck-Institute for Gravitational Physics, Callinstr. 38, D-30167 Hannover (Germany)

    2009-03-01

    This paper presents the implementation of an analog optical phase-locked-loop with an offset frequency of about 20MHz between two lasers, where the detected light powers were of the order of 31 pW and 200 muW. The goal of this setup was the design and characterization of a photodiode transimpedance amplifier for application in LISA. By application of a transimpedance amplifier designed to have low noise and low power consumption, the phase noise between the two lasers was a factor of two above the shot noise limit down to 60mHz. The achievable phase sensitivity depends ultimately on the available power of the highly attenuated master laser and on the input current noise of the transimpedance amplifier of the photodetector. The limiting noise source below 60mHz was the analog phase measurement system that was used in this experiment. A digital phase measurement system that is currently under development at the AEI will be used in the near future. Its application should improve the sensitivity.

  19. Apparatus for monitoring two-phase flow

    Science.gov (United States)

    Sheppard, John D.; Tong, Long S.

    1977-03-01

    A method and apparatus for monitoring two-phase flow is provided that is particularly related to the monitoring of transient two-phase (liquid-vapor) flow rates such as may occur during a pressurized water reactor core blow-down. The present invention essentially comprises the use of flanged wire screens or similar devices, such as perforated plates, to produce certain desirable effects in the flow regime for monitoring purposes. One desirable effect is a measurable and reproducible pressure drop across the screen. The pressure drop can be characterized for various known flow rates and then used to monitor nonhomogeneous flow regimes. Another useful effect of the use of screens or plates in nonhomogeneous flow is that such apparatus tends to create a uniformly dispersed flow regime in the immediate downstream vicinity. This is a desirable effect because it usually increases the accuracy of flow rate measurements determined by conventional methods.

  20. High-pressure phases of Weyl semimetals NbP, NbAs, TaP, and TaAs

    Science.gov (United States)

    Guo, ZhaoPeng; Lu, PengChao; Chen, Tong; Wu, JueFei; Sun, Jian; Xing, DingYu

    2018-03-01

    In this study, we used the crystal structure search method and first-principles calculations to systematically explore the highpressure phase diagrams of the TaAs family (NbP, NbAs, TaP, and TaAs). Our calculation results show that NbAs and TaAs have similar phase diagrams, the same structural phase transition sequence I41 md→ P6¯ m2→ P21/ c→ Pm3¯ m, and slightly different transition pressures. The phase transition sequence of NbP and TaP differs somewhat from that of NbAs and TaAs, in which new structures emerge, such as the Cmcm structure in NbP and the Pmmn structure in TaP. Interestingly, we found that in the electronic structure of the high-pressure phase P6¯ m2-NbAs, there are coexistingWeyl points and triple degenerate points, similar to those found in high-pressure P6¯ m2-TaAs.

  1. Void fraction prediction in two-phase flows independent of the liquid phase density changes

    International Nuclear Information System (INIS)

    Nazemi, E.; Feghhi, S.A.H.; Roshani, G.H.

    2014-01-01

    Gamma-ray densitometry is a frequently used non-invasive method to determine void fraction in two-phase gas liquid pipe flows. Performance of flow meters using gamma-ray attenuation depends strongly on the fluid properties. Variations of the fluid properties such as density in situations where temperature and pressure fluctuate would cause significant errors in determination of the void fraction in two-phase flows. A conventional solution overcoming such an obstacle is periodical recalibration which is a difficult task. This paper presents a method based on dual modality densitometry using Artificial Neural Network (ANN), which offers the advantage of measuring the void fraction independent of the liquid phase changes. An experimental setup was implemented to generate the required input data for training the network. ANNs were trained on the registered counts of the transmission and scattering detectors in different liquid phase densities and void fractions. Void fractions were predicted by ANNs with mean relative error of less than 0.45% in density variations range of 0.735 up to 0.98 gcm −3 . Applying this method would improve the performance of two-phase flow meters and eliminates the necessity of periodical recalibration. - Highlights: • Void fraction was predicted independent of density changes. • Recorded counts of detectors/void fraction were used as inputs/output of ANN. • ANN eliminated necessity of recalibration in changeable density of two-phase flows

  2. Two-point entanglement near a quantum phase transition

    International Nuclear Information System (INIS)

    Chen, Han-Dong

    2007-01-01

    In this work, we study the two-point entanglement S(i, j), which measures the entanglement between two separated degrees of freedom (ij) and the rest of system, near a quantum phase transition. Away from the critical point, S(i, j) saturates with a characteristic length scale ξ E , as the distance |i - j| increases. The entanglement length ξ E agrees with the correlation length. The universality and finite size scaling of entanglement are demonstrated in a class of exactly solvable one-dimensional spin model. By connecting the two-point entanglement to correlation functions in the long range limit, we argue that the prediction power of a two-point entanglement is universal as long as the two involved points are separated far enough

  3. TWO-PHASE EJECTOR of CARBON DIOXIDE HEAT PUMP CALCULUS

    Directory of Open Access Journals (Sweden)

    Sit B.M.

    2010-12-01

    Full Text Available It is presented the calculus of the two-phase ejector for carbon dioxide heat pump. The method of calculus is based on the method elaborated by S.M. Kandil, W.E. Lear, S.A. Sherif, and is modified taking into account entrainment ratio as the input for the calculus.

  4. Virtual mass effects in two-phase flow. Topical report

    International Nuclear Information System (INIS)

    Cheng, L.Y.; Drew, D.A.; Lahey, R.T. Jr.

    1978-03-01

    The effect of virtual mass on phase separation during the acceleration of a two-phase mixture was studied. Virtual mass can be regarded as an induced inertia on the dispersed phase which is accelerating relative to the continuous phase, and it was found that the virtual mass acceleration is objective, implying an invariance with respect to reference frame. An objective form of the virtual acceleration was derived and required parameters were determined for limiting cases. Analyses determined that experiments on single bubble nozzle/diffuser flow cannot readily discriminate between various virtual mass acceleration models

  5. Numerical calculation of two-phase flows

    International Nuclear Information System (INIS)

    Travis, J.R.; Harlow, F.H.; Amsden, A.A.

    1975-06-01

    The theoretical study of time-varying two-phase flow problems in several space dimensions introduces such a complicated set of coupled nonlinear partial differential equations that numerical solution procedures for high-speed computers are required in almost all but the simplest examples. Efficient attainment of realistic solutions for practical problems requires a finite- difference formulation that is simultaneously implicit in the treatment of mass convection, equations of state, and the momentum coupling between phases. Such a method is described, the equations on which it is based are discussed, and its properties are illustrated by means of examples. In particular, the capability for calculating physical instabilities and other time-varying dynamics, at the same time avoiding numerical instability is emphasized. The computer code is applicable to problems in reactor safety analysis, the dynamics of fluidized dust beds, raindrops or aerosol transport, and a variety of similar circumstances, including the effects of phase transitions and the release of latent heat or chemical energy. (U.S.)

  6. Spectral analysis of 5s25p2(6p+6d+7s) configurations of Ba VI

    International Nuclear Information System (INIS)

    Sharma, M.K.; Tauheed, A.; Rahimullah, K.

    2014-01-01

    The sixth spectrum of barium (Ba VI) has been investigated with the aid of experimental recordings made on a 3-m normal incidence vacuum spectrograph of Antigonish laboratory (Canada) in the wavelength region 300–2080 Å using triggered spark as an excitation source. The spectral analysis has been extended considerably to include new configuration the 5s 2 5p 2 6p in odd parity matrix and the 5s 2 5p 2 6d and 5s 2 5p 2 7s configurations in even parity matrix. Previously reported levels of the ground configuration (5s 2 5p 3 ) and three lowest excited configurations the 5s5p 4 , 5s 2 5p 2 5d and 5s 2 5p 2 6s have been confirmed and the two unknown levels of the 5s 2 5p 2 5d configuration with J=9/2, have now been established through the identification of transitions from the 5s 2 5p 2 6p levels. All twenty one levels of the 5s 2 5p 2 6p configuration and twenty nine levels out of thirty six of the 5s 2 5p 2 6d and 5s 2 5p 2 7s configurations have now been established. Hartree–Fock calculations involving configuration interactions support the analyses. The accuracy of our wavelength measurement is ±0.005 Å for sharp lines. - Highlights: • The spectrum of Ba was recorded on a 3-m spectrograph with triggered spark source. • Atomic transitions for Ba VI were identified to established new energy levels. • CI calculations with relativistic corrections were made for theoretical predictions. • Weighted oscillator strength (gf) and transition probabilities (gA) were calculated

  7. Research on one-dimensional two-phase flow

    International Nuclear Information System (INIS)

    Adachi, Hiromichi

    1988-10-01

    In Part I the fundamental form of the hydrodynamic basic equations for a one-dimensional two-phase flow (two-fluid model) is described. Discussions are concentrated on the treatment of phase change inertial force terms in the equations of motion and the author's equations of motion which have a remarkable uniqueness on the following three points. (1) To express force balance of unit mass two-phase fluid instead of that of unit volume two-phase fluid. (2) To pick up the unit existing mass and the unit flowing mass as the unit mass of two-phase fluid. (3) To apply the kinetic energy principle instead of the momentum low in the evaluation of steady inertial force term. In these three, the item (1) is for excluding a part of momentum change or kinetic energy change due to mass change of the examined part of fluid, which is independent of force. The item (2) is not to introduce a phenomenological physical model into the evaluation of phase change inertial force term. And the item (3) is for correctly applying the momentum law taking into account the difference of representative velocities between the main flow fluid (vapor phase or liquid phase) and the phase change part of fluid. In Part II, characteristics of various kinds of high speed two-phase flow are clarified theoretically by the basic equations derived. It is demonstrated that the steam-water two-phase critical flow with violent flashing and the airwater two-phase critical flow without phase change can be described with fundamentally the same basic equations. Furthermore, by comparing the experimental data from the two-phase critical discharge test and the theoretical prediction, the two-phase discharge coefficient, C D , for large sharp-edged orifice is determined as the value which is not affected by the experimental facility characteristics, etc. (author)

  8. Numerical simulation of two-phase flow with front-capturing

    International Nuclear Information System (INIS)

    Tzanos, C.P.; Weber, D.P.

    2000-01-01

    Because of the complexity of two-phase flow phenomena, two-phase flow codes rely heavily on empirical correlations. This approach has a number of serious shortcomings. Advances in parallel computing and continuing improvements in computer speed and memory have stimulated the development of numerical simulation tools that rely less on empirical correlations and more on fundamental physics. The objective of this work is to take advantage of developments in massively parallel computing, single-phase computational fluid dynamics of complex systems, and numerical methods for front capturing in two-phase flows to develop a computer code for direct numerical simulation of two-phase flow. This includes bubble/droplet transport, interface deformation and topology change, bubble-droplet interactions, interface mass, momentum, and energy transfer. In this work, the Navier-Stokes and energy equations are solved by treating both phases as a single fluid with interfaces between the two phases, and a discontinuity in material properties across the moving interfaces. The evolution of the interfaces is simulated by using the front capturing technique of the level-set methods. In these methods, the boundary of a two-fluid interface is modeled as the zero level set of a smooth function φ. The level-set function φ is defined as the signed distance from the interface (φ is negative inside a droplet/bubble and positive outside). Compared to other front-capturing or front-tracking methods, the level-set approach is relatively easy to implement even in three-dimensional flows, and it has been shown to simulate well the coalescence and breakup of droplets/bubbles

  9. Radiative lifetimes and two-body collisional deactivation rate constants in argon for Kr(4p 55p) and Kr(4p 55p') states

    International Nuclear Information System (INIS)

    Chang, R.S.F.; Horiguchi, H.; Setser, D.W.

    1980-01-01

    The radiative lifetimes and collisional deactivation rate constants, in argon, of eight Kr(4p 5 [ 2 P/sub 1/2/]5p and [ 2 P/sub 3/2/]5p) levels have been measured by a time-resolved laser-induced fluorescence technique in a flowing afterglow apparatus. The measured radiative lifetimes are compared with other experimental values and with theoretical calculations. Radiative branching ratios of these excited states also were measured in order to assign the absolute transition probabilities of the Kr(5p,5p'--5s, 5s') transition array from the radiative lifetimes. In addition to the total deactivation rate constants, product states from two-body collisions between Kr(5p and 5p') atoms and ground state argon atoms were identified from the laser-induced emission spectra, and product formation rate constants were assigned. Two-body intermultiplet transfer from Kr(4p 5 [ 2 P/sub 1/2/]5p) to the Kr(4p 5 [ 2 P/sub 3/2/]4d) levels occurs with ease. Intermultiplet transfer from the lowest level in the (4p 5 5p) configuration to the Kr(4p 5 5s and 5s') manifold was fast despite the large energy defect. However, this was the only Kr(5p) level that gave appreciable transfer to the Kr(5s or 5s') manifold. Generally the favored product states are within a few kT of the entrance channel

  10. Measurement of the production cross section ratio $\\sigma(\\chi_{b2}(1\\mathrm{P}))/ \\sigma(\\chi_{b1}(1\\mathrm{P}))$ in pp collisions at $\\sqrt{s}$ = 8 TeV

    CERN Document Server

    Khachatryan, Vardan; Tumasyan, Armen; Adam, Wolfgang; Bergauer, Thomas; Dragicevic, Marko; Erö, Janos; Fabjan, Christian; Friedl, Markus; Fruehwirth, Rudolf; Ghete, Vasile Mihai; Hartl, Christian; Hörmann, Natascha; Hrubec, Josef; Jeitler, Manfred; Kiesenhofer, Wolfgang; Knünz, Valentin; Krammer, Manfred; Krätschmer, Ilse; Liko, Dietrich; Mikulec, Ivan; Rabady, Dinyar; Rahbaran, Babak; Rohringer, Herbert; Schöfbeck, Robert; Strauss, Josef; Taurok, Anton; Treberer-Treberspurg, Wolfgang; Waltenberger, Wolfgang; Wulz, Claudia-Elisabeth; Mossolov, Vladimir; Shumeiko, Nikolai; Suarez Gonzalez, Juan; Alderweireldt, Sara; Bansal, Monika; Bansal, Sunil; Cornelis, Tom; De Wolf, Eddi A; Janssen, Xavier; Knutsson, Albert; Luyckx, Sten; Ochesanu, Silvia; Roland, Benoit; Rougny, Romain; Van De Klundert, Merijn; Van Haevermaet, Hans; Van Mechelen, Pierre; Van Remortel, Nick; Van Spilbeeck, Alex; Blekman, Freya; Blyweert, Stijn; D'Hondt, Jorgen; Daci, Nadir; Heracleous, Natalie; Keaveney, James; Lowette, Steven; Maes, Michael; Olbrechts, Annik; Python, Quentin; Strom, Derek; Tavernier, Stefaan; Van Doninck, Walter; Van Mulders, Petra; Van Onsem, Gerrit Patrick; Villella, Ilaria; Caillol, Cécile; Clerbaux, Barbara; De Lentdecker, Gilles; Dobur, Didar; Favart, Laurent; Gay, Arnaud; Grebenyuk, Anastasia; Léonard, Alexandre; Mohammadi, Abdollah; Perniè, Luca; Reis, Thomas; Seva, Tomislav; Thomas, Laurent; Vander Velde, Catherine; Vanlaer, Pascal; Wang, Jian; Adler, Volker; Beernaert, Kelly; Benucci, Leonardo; Cimmino, Anna; Costantini, Silvia; Crucy, Shannon; Dildick, Sven; Fagot, Alexis; Garcia, Guillaume; Mccartin, Joseph; Ocampo Rios, Alberto Andres; Ryckbosch, Dirk; Salva Diblen, Sinem; Sigamani, Michael; Strobbe, Nadja; Thyssen, Filip; Tytgat, Michael; Yazgan, Efe; Zaganidis, Nicolas; Basegmez, Suzan; Beluffi, Camille; Bruno, Giacomo; Castello, Roberto; Caudron, Adrien; Ceard, Ludivine; Da Silveira, Gustavo Gil; Delaere, Christophe; Du Pree, Tristan; Favart, Denis; Forthomme, Laurent; Giammanco, Andrea; Hollar, Jonathan; Jez, Pavel; Komm, Matthias; Lemaitre, Vincent; Nuttens, Claude; Pagano, Davide; Perrini, Lucia; Pin, Arnaud; Piotrzkowski, Krzysztof; Popov, Andrey; Quertenmont, Loic; Selvaggi, Michele; Vidal Marono, Miguel; Vizan Garcia, Jesus Manuel; Beliy, Nikita; Caebergs, Thierry; Daubie, Evelyne; Hammad, Gregory Habib; Aldá Júnior, Walter Luiz; Alves, Gilvan; Brito, Lucas; Correa Martins Junior, Marcos; Dos Reis Martins, Thiago; Mora Herrera, Clemencia; Pol, Maria Elena; Carvalho, Wagner; Chinellato, Jose; Custódio, Analu; Melo Da Costa, Eliza; De Jesus Damiao, Dilson; De Oliveira Martins, Carley; Fonseca De Souza, Sandro; Malbouisson, Helena; Matos Figueiredo, Diego; Mundim, Luiz; Nogima, Helio; Prado Da Silva, Wanda Lucia; Santaolalla, Javier; Santoro, Alberto; Sznajder, Andre; Tonelli Manganote, Edmilson José; Vilela Pereira, Antonio; Bernardes, Cesar Augusto; Dogra, Sunil; Tomei, Thiago; De Moraes Gregores, Eduardo; Mercadante, Pedro G; Novaes, Sergio F; Padula, Sandra; Aleksandrov, Aleksandar; Genchev, Vladimir; Iaydjiev, Plamen; Marinov, Andrey; Piperov, Stefan; Rodozov, Mircho; Stoykova, Stefka; Sultanov, Georgi; Tcholakov, Vanio; Vutova, Mariana; Dimitrov, Anton; Glushkov, Ivan; Hadjiiska, Roumyana; Kozhuharov, Venelin; Litov, Leander; Pavlov, Borislav; Petkov, Peicho; Bian, Jian-Guo; Chen, Guo-Ming; Chen, He-Sheng; Chen, Mingshui; Du, Ran; Jiang, Chun-Hua; Liang, Song; Plestina, Roko; Tao, Junquan; Wang, Xianyou; Wang, Zheng; Asawatangtrakuldee, Chayanit; Ban, Yong; Guo, Yifei; Li, Qiang; Li, Wenbo; Liu, Shuai; Mao, Yajun; Qian, Si-Jin; Wang, Dayong; Zhang, Linlin; Zou, Wei; Avila, Carlos; Chaparro Sierra, Luisa Fernanda; Florez, Carlos; Gomez, Juan Pablo; Gomez Moreno, Bernardo; Sanabria, Juan Carlos; Godinovic, Nikola; Lelas, Damir; Polic, Dunja; Puljak, Ivica; Antunovic, Zeljko; Kovac, Marko; Brigljevic, Vuko; Kadija, Kreso; Luetic, Jelena; Mekterovic, Darko; Sudic, Lucija; Attikis, Alexandros; Mavromanolakis, Georgios; Mousa, Jehad; Nicolaou, Charalambos; Ptochos, Fotios; Razis, Panos A; Bodlak, Martin; Finger, Miroslav; Finger Jr, Michael; Assran, Yasser; Ellithi Kamel, Ali; Mahmoud, Mohammed; Radi, Amr; Kadastik, Mario; Murumaa, Marion; Raidal, Martti; Tiko, Andres; Eerola, Paula; Fedi, Giacomo; Voutilainen, Mikko; Härkönen, Jaakko; Karimäki, Veikko; Kinnunen, Ritva; Kortelainen, Matti J; Lampén, Tapio; Lassila-Perini, Kati; Lehti, Sami; Lindén, Tomas; Luukka, Panja-Riina; Mäenpää, Teppo; Peltola, Timo; Tuominen, Eija; Tuominiemi, Jorma; Tuovinen, Esa; Wendland, Lauri; Tuuva, Tuure; Besancon, Marc; Couderc, Fabrice; Dejardin, Marc; Denegri, Daniel; Fabbro, Bernard; Faure, Jean-Louis; Favaro, Carlotta; Ferri, Federico; Ganjour, Serguei; Givernaud, Alain; Gras, Philippe; Hamel de Monchenault, Gautier; Jarry, Patrick; Locci, Elizabeth; Malcles, Julie; Rander, John; Rosowsky, André; Titov, Maksym; Baffioni, Stephanie; Beaudette, Florian; Busson, Philippe; Charlot, Claude; Dahms, Torsten; Dalchenko, Mykhailo; Dobrzynski, Ludwik; Filipovic, Nicolas; Florent, Alice; Granier de Cassagnac, Raphael; Mastrolorenzo, Luca; Miné, Philippe; Mironov, Camelia; Naranjo, Ivo Nicolas; Nguyen, Matthew; Ochando, Christophe; Paganini, Pascal; Regnard, Simon; Salerno, Roberto; Sauvan, Jean-Baptiste; Sirois, Yves; Veelken, Christian; Yilmaz, Yetkin; Zabi, Alexandre; Agram, Jean-Laurent; Andrea, Jeremy; Aubin, Alexandre; Bloch, Daniel; Brom, Jean-Marie; Chabert, Eric Christian; Collard, Caroline; Conte, Eric; Fontaine, Jean-Charles; Gelé, Denis; Goerlach, Ulrich; Goetzmann, Christophe; Le Bihan, Anne-Catherine; Van Hove, Pierre; Gadrat, Sébastien; Beauceron, Stephanie; Beaupere, Nicolas; Boudoul, Gaelle; Bouvier, Elvire; Brochet, Sébastien; Carrillo Montoya, Camilo Andres; Chasserat, Julien; Chierici, Roberto; Contardo, Didier; Depasse, Pierre; El Mamouni, Houmani; Fan, Jiawei; Fay, Jean; Gascon, Susan; Gouzevitch, Maxime; Ille, Bernard; Kurca, Tibor; Lethuillier, Morgan; Mirabito, Laurent; Perries, Stephane; Ruiz Alvarez, José David; Sabes, David; Sgandurra, Louis; Sordini, Viola; Vander Donckt, Muriel; Verdier, Patrice; Viret, Sébastien; Xiao, Hong; Tsamalaidze, Zviad; Autermann, Christian; Beranek, Sarah; Bontenackels, Michael; Edelhoff, Matthias; Feld, Lutz; Hindrichs, Otto; Klein, Katja; Ostapchuk, Andrey; Perieanu, Adrian; Raupach, Frank; Sammet, Jan; Schael, Stefan; Weber, Hendrik; Wittmer, Bruno; Zhukov, Valery; Ata, Metin; Dietz-Laursonn, Erik; Duchardt, Deborah; Erdmann, Martin; Fischer, Robert; Güth, Andreas; Hebbeker, Thomas; Heidemann, Carsten; Hoepfner, Kerstin; Klingebiel, Dennis; Knutzen, Simon; Kreuzer, Peter; Merschmeyer, Markus; Meyer, Arnd; Millet, Philipp; Olschewski, Mark; Padeken, Klaas; Papacz, Paul; Reithler, Hans; Schmitz, Stefan Antonius; Sonnenschein, Lars; Teyssier, Daniel; Thüer, Sebastian; Weber, Martin; Cherepanov, Vladimir; Erdogan, Yusuf; Flügge, Günter; Geenen, Heiko; Geisler, Matthias; Haj Ahmad, Wael; Heister, Arno; Hoehle, Felix; Kargoll, Bastian; Kress, Thomas; Kuessel, Yvonne; Lingemann, Joschka; Nowack, Andreas; Nugent, Ian Michael; Perchalla, Lars; Pooth, Oliver; Stahl, Achim; Asin, Ivan; Bartosik, Nazar; Behr, Joerg; Behrenhoff, Wolf; Behrens, Ulf; Bell, Alan James; Bergholz, Matthias; Bethani, Agni; Borras, Kerstin; Burgmeier, Armin; Cakir, Altan; Calligaris, Luigi; Campbell, Alan; Choudhury, Somnath; Costanza, Francesco; Diez Pardos, Carmen; Dooling, Samantha; Dorland, Tyler; Eckerlin, Guenter; Eckstein, Doris; Eichhorn, Thomas; Flucke, Gero; Garay Garcia, Jasone; Geiser, Achim; Gunnellini, Paolo; Hauk, Johannes; Hempel, Maria; Horton, Dean; Jung, Hannes; Kalogeropoulos, Alexis; Kasemann, Matthias; Katsas, Panagiotis; Kieseler, Jan; Kleinwort, Claus; Krücker, Dirk; Lange, Wolfgang; Leonard, Jessica; Lipka, Katerina; Lobanov, Artur; Lohmann, Wolfgang; Lutz, Benjamin; Mankel, Rainer; Marfin, Ihar; Melzer-Pellmann, Isabell-Alissandra; Meyer, Andreas Bernhard; Mittag, Gregor; Mnich, Joachim; Mussgiller, Andreas; Naumann-Emme, Sebastian; Nayak, Aruna; Novgorodova, Olga; Nowak, Friederike; Ntomari, Eleni; Perrey, Hanno; Pitzl, Daniel; Placakyte, Ringaile; Raspereza, Alexei; Ribeiro Cipriano, Pedro M; Ron, Elias; Sahin, Mehmet Özgür; Salfeld-Nebgen, Jakob; Saxena, Pooja; Schmidt, Ringo; Schoerner-Sadenius, Thomas; Schröder, Matthias; Seitz, Claudia; Spannagel, Simon; Vargas Trevino, Andrea Del Rocio; Walsh, Roberval; Wissing, Christoph; Aldaya Martin, Maria; Blobel, Volker; Centis Vignali, Matteo; Draeger, Arne-Rasmus; Erfle, Joachim; Garutti, Erika; Goebel, Kristin; Görner, Martin; Haller, Johannes; Hoffmann, Malte; Höing, Rebekka Sophie; Kirschenmann, Henning; Klanner, Robert; Kogler, Roman; Lange, Jörn; Lapsien, Tobias; Lenz, Teresa; Marchesini, Ivan; Ott, Jochen; Peiffer, Thomas; Pietsch, Niklas; Poehlsen, Jennifer; Pöhlsen, Thomas; Rathjens, Denis; Sander, Christian; Schettler, Hannes; Schleper, Peter; Schlieckau, Eike; Schmidt, Alexander; Seidel, Markus; Sola, Valentina; Stadie, Hartmut; Steinbrück, Georg; Troendle, Daniel; Usai, Emanuele; Vanelderen, Lukas; Barth, Christian; Baus, Colin; Berger, Joram; Böser, Christian; Butz, Erik; Chwalek, Thorsten; De Boer, Wim; Descroix, Alexis; Dierlamm, Alexander; Feindt, Michael; Frensch, Felix; Giffels, Manuel; Hartmann, Frank; Hauth, Thomas; Husemann, Ulrich; Katkov, Igor; Kornmayer, Andreas; Kuznetsova, Ekaterina; Lobelle Pardo, Patricia; Mozer, Matthias Ulrich; Müller, Thomas; Nürnberg, Andreas; Quast, Gunter; Rabbertz, Klaus; Ratnikov, Fedor; Röcker, Steffen; Simonis, Hans-Jürgen; Stober, Fred-Markus Helmut; Ulrich, Ralf; Wagner-Kuhr, Jeannine; Wayand, Stefan; Weiler, Thomas; Wolf, Roger; Anagnostou, Georgios; Daskalakis, Georgios; Geralis, Theodoros; Giakoumopoulou, Viktoria Athina; Kyriakis, Aristotelis; Loukas, Demetrios; Markou, Athanasios; Markou, Christos; Psallidas, Andreas; Topsis-Giotis, Iasonas; Kesisoglou, Stilianos; Panagiotou, Apostolos; Saoulidou, Niki; Stiliaris, Efstathios; Aslanoglou, Xenofon; Evangelou, Ioannis; Flouris, Giannis; Foudas, Costas; Kokkas, Panagiotis; Manthos, Nikolaos; Papadopoulos, Ioannis; Paradas, Evangelos; Bencze, Gyorgy; Hajdu, Csaba; Hidas, Pàl; Horvath, Dezso; Sikler, Ferenc; Veszpremi, Viktor; Vesztergombi, Gyorgy; Zsigmond, Anna Julia; Beni, Noemi; Czellar, Sandor; Karancsi, János; Molnar, Jozsef; Palinkas, Jozsef; Szillasi, Zoltan; Raics, Peter; Trocsanyi, Zoltan Laszlo; Ujvari, Balazs; Swain, Sanjay Kumar; Beri, Suman Bala; Bhatnagar, Vipin; Dhingra, Nitish; Gupta, Ruchi; Bhawandeep, Bhawandeep; Kalsi, Amandeep Kaur; Kaur, Manjit; Mittal, Monika; Nishu, Nishu; Singh, Jasbir; Kumar, Ashok; Kumar, Arun; Ahuja, Sudha; Bhardwaj, Ashutosh; Choudhary, Brajesh C; Kumar, Ajay; Malhotra, Shivali; Naimuddin, Md; Ranjan, Kirti; Sharma, Varun; Banerjee, Sunanda; Bhattacharya, Satyaki; Chatterjee, Kalyanmoy; Dutta, Suchandra; Gomber, Bhawna; Jain, Sandhya; Jain, Shilpi; Khurana, Raman; Modak, Atanu; Mukherjee, Swagata; Roy, Debarati; Sarkar, Subir; Sharan, Manoj; Abdulsalam, Abdulla; Dutta, Dipanwita; Kailas, Swaminathan; Kumar, Vineet; Mohanty, Ajit Kumar; Pant, Lalit Mohan; Shukla, Prashant; Topkar, Anita; Aziz, Tariq; Banerjee, Sudeshna; Bhowmik, Sandeep; Chatterjee, Rajdeep Mohan; Dewanjee, Ram Krishna; Dugad, Shashikant; Ganguly, Sanmay; Ghosh, Saranya; Guchait, Monoranjan; Gurtu, Atul; Kole, Gouranga; Kumar, Sanjeev; Maity, Manas; Majumder, Gobinda; Mazumdar, Kajari; Mohanty, Gagan Bihari; Parida, Bibhuti; Sudhakar, Katta; Wickramage, Nadeesha; Bakhshiansohi, Hamed; Behnamian, Hadi; Etesami, Seyed Mohsen; Fahim, Ali; Goldouzian, Reza; Jafari, Abideh; Khakzad, Mohsen; Mohammadi Najafabadi, Mojtaba; Naseri, Mohsen; Paktinat Mehdiabadi, Saeid; Rezaei Hosseinabadi, Ferdos; Safarzadeh, Batool; Zeinali, Maryam; Felcini, Marta; Grunewald, Martin; Abbrescia, Marcello; Barbone, Lucia; Calabria, Cesare; Chhibra, Simranjit Singh; Colaleo, Anna; Creanza, Donato; De Filippis, Nicola; De Palma, Mauro; Fiore, Luigi; Iaselli, Giuseppe; Maggi, Giorgio; Maggi, Marcello; My, Salvatore; Nuzzo, Salvatore; Pompili, Alexis; Pugliese, Gabriella; Radogna, Raffaella; Selvaggi, Giovanna; Silvestris, Lucia; Singh, Gurpreet; Venditti, Rosamaria; Verwilligen, Piet; Zito, Giuseppe; Abbiendi, Giovanni; Benvenuti, Alberto; Bonacorsi, Daniele; Braibant-Giacomelli, Sylvie; Brigliadori, Luca; Campanini, Renato; Capiluppi, Paolo; Castro, Andrea; Cavallo, Francesca Romana; Codispoti, Giuseppe; Cuffiani, Marco; Dallavalle, Gaetano-Marco; Fabbri, Fabrizio; Fanfani, Alessandra; Fasanella, Daniele; Giacomelli, Paolo; Grandi, Claudio; Guiducci, Luigi; Marcellini, Stefano; Masetti, Gianni; Montanari, Alessandro; Navarria, Francesco; Perrotta, Andrea; Primavera, Federica; Rossi, Antonio; Rovelli, Tiziano; Siroli, Gian Piero; Tosi, Nicolò; Travaglini, Riccardo; Albergo, Sebastiano; Cappello, Gigi; Chiorboli, Massimiliano; Costa, Salvatore; Giordano, Ferdinando; Potenza, Renato; Tricomi, Alessia; Tuve, Cristina; Barbagli, Giuseppe; Ciulli, Vitaliano; Civinini, Carlo; D'Alessandro, Raffaello; Focardi, Ettore; Gallo, Elisabetta; Gonzi, Sandro; Gori, Valentina; Lenzi, Piergiulio; Meschini, Marco; Paoletti, Simone; Sguazzoni, Giacomo; Tropiano, Antonio; Benussi, Luigi; Bianco, Stefano; Fabbri, Franco; Piccolo, Davide; Ferro, Fabrizio; Lo Vetere, Maurizio; Robutti, Enrico; Tosi, Silvano; Dinardo, Mauro Emanuele; Fiorendi, Sara; Gennai, Simone; Gerosa, Raffaele; Ghezzi, Alessio; Govoni, Pietro; Lucchini, Marco Toliman; Malvezzi, Sandra; Manzoni, Riccardo Andrea; Martelli, Arabella; Marzocchi, Badder; Menasce, Dario; Moroni, Luigi; Paganoni, Marco; Pedrini, Daniele; Ragazzi, Stefano; Redaelli, Nicola; Tabarelli de Fatis, Tommaso; Buontempo, Salvatore; Cavallo, Nicola; Di Guida, Salvatore; Fabozzi, Francesco; Iorio, Alberto Orso Maria; Lista, Luca; Meola, Sabino; Merola, Mario; Paolucci, Pierluigi; Azzi, Patrizia; Bacchetta, Nicola; Bisello, Dario; Branca, Antonio; Carlin, Roberto; Checchia, Paolo; Dall'Osso, Martino; Dorigo, Tommaso; Dosselli, Umberto; Galanti, Mario; Gasparini, Fabrizio; Gasparini, Ugo; Giubilato, Piero; Gonella, Franco; Gozzelino, Andrea; Kanishchev, Konstantin; Lacaprara, Stefano; Margoni, Martino; Montecassiano, Fabio; Pazzini, Jacopo; Pozzobon, Nicola; Ronchese, Paolo; Simonetto, Franco; Tosi, Mia; Zotto, Pierluigi; Zucchetta, Alberto; Zumerle, Gianni; Gabusi, Michele; Ratti, Sergio P; Riccardi, Cristina; Salvini, Paola; Vitulo, Paolo; Biasini, Maurizio; Bilei, Gian Mario; Ciangottini, Diego; Fanò, Livio; Lariccia, Paolo; Mantovani, Giancarlo; Menichelli, Mauro; Romeo, Francesco; Saha, Anirban; Santocchia, Attilio; Spiezia, Aniello; Androsov, Konstantin; Azzurri, Paolo; Bagliesi, Giuseppe; Bernardini, Jacopo; Boccali, Tommaso; Broccolo, Giuseppe; Castaldi, Rino; Ciocci, Maria Agnese; Dell'Orso, Roberto; Donato, Silvio; Fiori, Francesco; Foà, Lorenzo; Giassi, Alessandro; Grippo, Maria Teresa; Ligabue, Franco; Lomtadze, Teimuraz; Martini, Luca; Messineo, Alberto; Moon, Chang-Seong; Palla, Fabrizio; Rizzi, Andrea; Savoy-Navarro, Aurore; Serban, Alin Titus; Spagnolo, Paolo; Squillacioti, Paola; Tenchini, Roberto; Tonelli, Guido; Venturi, Andrea; Verdini, Piero Giorgio; Vernieri, Caterina; Barone, Luciano; Cavallari, Francesca; D'imperio, Giulia; Del Re, Daniele; Diemoz, Marcella; Grassi, Marco; Jorda, Clara; Longo, Egidio; Margaroli, Fabrizio; Meridiani, Paolo; Micheli, Francesco; Nourbakhsh, Shervin; Organtini, Giovanni; Paramatti, Riccardo; Rahatlou, Shahram; Rovelli, Chiara; Santanastasio, Francesco; Soffi, Livia; Traczyk, Piotr; Amapane, Nicola; Arcidiacono, Roberta; Argiro, Stefano; Arneodo, Michele; Bellan, Riccardo; Biino, Cristina; Cartiglia, Nicolo; Casasso, Stefano; Costa, Marco; Degano, Alessandro; Demaria, Natale; Dujany, Giulio; Finco, Linda; Mariotti, Chiara; Maselli, Silvia; Migliore, Ernesto; Monaco, Vincenzo; Musich, Marco; Obertino, Maria Margherita; Ortona, Giacomo; Pacher, Luca; Pastrone, Nadia; Pelliccioni, Mario; Pinna Angioni, Gian Luca; Potenza, Alberto; Romero, Alessandra; Ruspa, Marta; Sacchi, Roberto; Solano, Ada; Staiano, Amedeo; Tamponi, Umberto; Belforte, Stefano; Candelise, Vieri; Casarsa, Massimo; Cossutti, Fabio; Della Ricca, Giuseppe; Gobbo, Benigno; La Licata, Chiara; Marone, Matteo; Montanino, Damiana; Schizzi, Andrea; Umer, Tomo; Zanetti, Anna; Chang, Sunghyun; Kropivnitskaya, Anna; Nam, Soon-Kwon; Kim, Dong Hee; Kim, Gui Nyun; Kim, Min Suk; Kong, Dae Jung; Lee, Sangeun; Oh, Young Do; Park, Hyangkyu; Sakharov, Alexandre; Son, Dong-Chul; Kim, Tae Jeong; Kim, Jae Yool; Song, Sanghyeon; Choi, Suyong; Gyun, Dooyeon; Hong, Byung-Sik; Jo, Mihee; Kim, Hyunchul; Kim, Yongsun; Lee, Byounghoon; Lee, Kyong Sei; Park, Sung Keun; Roh, Youn; Choi, Minkyoo; Kim, Ji Hyun; Park, Inkyu; Park, Sangnam; Ryu, Geonmo; Ryu, Min Sang; Choi, Young-Il; Choi, Young Kyu; Goh, Junghwan; Kim, Donghyun; Kwon, Eunhyang; Lee, Jongseok; Seo, Hyunkwan; Yu, Intae; Juodagalvis, Andrius; Komaragiri, Jyothsna Rani; Md Ali, Mohd Adli Bin; Castilla-Valdez, Heriberto; De La Cruz-Burelo, Eduard; Heredia-de La Cruz, Ivan; Lopez-Fernandez, Ricardo; Sánchez Hernández, Alberto; Carrillo Moreno, Salvador; Vazquez Valencia, Fabiola; Pedraza, Isabel; Salazar Ibarguen, Humberto Antonio; Casimiro Linares, Edgar; Morelos Pineda, Antonio; Krofcheck, David; Butler, Philip H; Reucroft, Steve; Ahmad, Ashfaq; Ahmad, Muhammad; Hassan, Qamar; Hoorani, Hafeez R; Khalid, Shoaib; Khan, Wajid Ali; Khurshid, Taimoor; Shah, Mehar Ali; Shoaib, Muhammad; Bialkowska, Helena; Bluj, Michal; Boimska, Bożena; Frueboes, Tomasz; Górski, Maciej; Kazana, Malgorzata; Nawrocki, Krzysztof; Romanowska-Rybinska, Katarzyna; Szleper, Michal; Zalewski, Piotr; Brona, Grzegorz; Bunkowski, Karol; Cwiok, Mikolaj; Dominik, Wojciech; Doroba, Krzysztof; Kalinowski, Artur; Konecki, Marcin; Krolikowski, Jan; Misiura, Maciej; Olszewski, Michał; Wolszczak, Weronika; Bargassa, Pedrame; Beirão Da Cruz E Silva, Cristóvão; Faccioli, Pietro; Ferreira Parracho, Pedro Guilherme; Gallinaro, Michele; Nguyen, Federico; Rodrigues Antunes, Joao; Seixas, Joao; Varela, Joao; Vischia, Pietro; Golutvin, Igor; Gorbunov, Ilya; Karjavin, Vladimir; Konoplyanikov, Viktor; Korenkov, Vladimir; Lanev, Alexander; Malakhov, Alexander; Matveev, Viktor; Mitsyn, Valeri Valentinovitch; Moisenz, Petr; Palichik, Vladimir; Perelygin, Victor; Shmatov, Sergey; Skatchkov, Nikolai; Smirnov, Vitaly; Tikhonenko, Elena; Yuldashev, Bekhzod S; Zarubin, Anatoli; Golovtsov, Victor; Ivanov, Yury; Kim, Victor; Levchenko, Petr; Murzin, Victor; Oreshkin, Vadim; Smirnov, Igor; Sulimov, Valentin; Uvarov, Lev; Vavilov, Sergey; Vorobyev, Alexey; Vorobyev, Andrey; Andreev, Yuri; Dermenev, Alexander; Gninenko, Sergei; Golubev, Nikolai; Kirsanov, Mikhail; Krasnikov, Nikolai; Pashenkov, Anatoli; Tlisov, Danila; Toropin, Alexander; Epshteyn, Vladimir; Gavrilov, Vladimir; Lychkovskaya, Natalia; Popov, Vladimir; Safronov, Grigory; Semenov, Sergey; Spiridonov, Alexander; Stolin, Viatcheslav; Vlasov, Evgueni; Zhokin, Alexander; Andreev, Vladimir; Azarkin, Maksim; Dremin, Igor; Kirakosyan, Martin; Leonidov, Andrey; Mesyats, Gennady; Rusakov, Sergey V; Vinogradov, Alexey; Belyaev, Andrey; Boos, Edouard; Dubinin, Mikhail; Dudko, Lev; Ershov, Alexander; Gribushin, Andrey; Klyukhin, Vyacheslav; Kodolova, Olga; Lokhtin, Igor; Obraztsov, Stepan; Petrushanko, Sergey; Savrin, Viktor; Snigirev, Alexander; Azhgirey, Igor; Bayshev, Igor; Bitioukov, Sergei; Kachanov, Vassili; Kalinin, Alexey; Konstantinov, Dmitri; Krychkine, Victor; Petrov, Vladimir; Ryutin, Roman; Sobol, Andrei; Tourtchanovitch, Leonid; Troshin, Sergey; Tyurin, Nikolay; Uzunian, Andrey; Volkov, Alexey; Adzic, Petar; Ekmedzic, Marko; Milosevic, Jovan; Rekovic, Vladimir; Alcaraz Maestre, Juan; Battilana, Carlo; Calvo, Enrique; Cerrada, Marcos; Chamizo Llatas, Maria; Colino, Nicanor; De La Cruz, Begona; Delgado Peris, Antonio; Domínguez Vázquez, Daniel; Escalante Del Valle, Alberto; Fernandez Bedoya, Cristina; Fernández Ramos, Juan Pablo; Flix, Jose; Fouz, Maria Cruz; Garcia-Abia, Pablo; Gonzalez Lopez, Oscar; Goy Lopez, Silvia; Hernandez, Jose M; Josa, Maria Isabel; Merino, Gonzalo; Navarro De Martino, Eduardo; Pérez Calero Yzquierdo, Antonio María; Puerta Pelayo, Jesus; Quintario Olmeda, Adrián; Redondo, Ignacio; Romero, Luciano; Senghi Soares, Mara; Albajar, Carmen; de Trocóniz, Jorge F; Missiroli, Marino; Moran, Dermot; Brun, Hugues; Cuevas, Javier; Fernandez Menendez, Javier; Folgueras, Santiago; Gonzalez Caballero, Isidro; Lloret Iglesias, Lara; Brochero Cifuentes, Javier Andres; Cabrillo, Iban Jose; Calderon, Alicia; Duarte Campderros, Jordi; Fernandez, Marcos; Gomez, Gervasio; Graziano, Alberto; Lopez Virto, Amparo; Marco, Jesus; Marco, Rafael; Martinez Rivero, Celso; Matorras, Francisco; Munoz Sanchez, Francisca Javiela; Piedra Gomez, Jonatan; Rodrigo, Teresa; Rodríguez-Marrero, Ana Yaiza; Ruiz-Jimeno, Alberto; Scodellaro, Luca; Vila, Ivan; Vilar Cortabitarte, Rocio; Abbaneo, Duccio; Auffray, Etiennette; Auzinger, Georg; Bachtis, Michail; Baillon, Paul; Ball, Austin; Barney, David; Benaglia, Andrea; Bendavid, Joshua; Benhabib, Lamia; Benitez, Jose F; Bernet, Colin; Bianchi, Giovanni; Bloch, Philippe; Bocci, Andrea; Bonato, Alessio; Bondu, Olivier; Botta, Cristina; Breuker, Horst; Camporesi, Tiziano; Cerminara, Gianluca; Colafranceschi, Stefano; D'Alfonso, Mariarosaria; D'Enterria, David; Dabrowski, Anne; David Tinoco Mendes, Andre; De Guio, Federico; De Roeck, Albert; De Visscher, Simon; Dobson, Marc; Dordevic, Milos; Dupont-Sagorin, Niels; Elliott-Peisert, Anna; Eugster, Jürg; Franzoni, Giovanni; Funk, Wolfgang; Gigi, Dominique; Gill, Karl; Giordano, Domenico; Girone, Maria; Glege, Frank; Guida, Roberto; Gundacker, Stefan; Guthoff, Moritz; Hammer, Josef; Hansen, Magnus; Harris, Philip; Hegeman, Jeroen; Innocente, Vincenzo; Janot, Patrick; Kousouris, Konstantinos; Krajczar, Krisztian; Lecoq, Paul; Lourenco, Carlos; Magini, Nicolo; Malgeri, Luca; Mannelli, Marcello; Marrouche, Jad; Masetti, Lorenzo; Meijers, Frans; Mersi, Stefano; Meschi, Emilio; Moortgat, Filip; Morovic, Srecko; Mulders, Martijn; Musella, Pasquale; Orsini, Luciano; Pape, Luc; Perez, Emmanuelle; Perrozzi, Luca; Petrilli, Achille; Petrucciani, Giovanni; Pfeiffer, Andreas; Pierini, Maurizio; Pimiä, Martti; Piparo, Danilo; Plagge, Michael; Racz, Attila; Rolandi, Gigi; Rovere, Marco; Sakulin, Hannes; Schäfer, Christoph; Schwick, Christoph; Sharma, Archana; Siegrist, Patrice; Silva, Pedro; Simon, Michal; Sphicas, Paraskevas; Spiga, Daniele; Steggemann, Jan; Stieger, Benjamin; Stoye, Markus; Treille, Daniel; Tsirou, Andromachi; Veres, Gabor Istvan; Vlimant, Jean-Roch; Wardle, Nicholas; Wöhri, Hermine Katharina; Wollny, Heiner; Zeuner, Wolfram Dietrich; Bertl, Willi; Deiters, Konrad; Erdmann, Wolfram; Horisberger, Roland; Ingram, Quentin; Kaestli, Hans-Christian; Kotlinski, Danek; Langenegger, Urs; Renker, Dieter; Rohe, Tilman; Bachmair, Felix; Bäni, Lukas; Bianchini, Lorenzo; Bortignon, Pierluigi; Buchmann, Marco-Andrea; Casal, Bruno; Chanon, Nicolas; Deisher, Amanda; Dissertori, Günther; Dittmar, Michael; Donegà, Mauro; Dünser, Marc; Eller, Philipp; Grab, Christoph; Hits, Dmitry; Lustermann, Werner; Mangano, Boris; Marini, Andrea Carlo; Martinez Ruiz del Arbol, Pablo; Meister, Daniel; Mohr, Niklas; Nägeli, Christoph; Nessi-Tedaldi, Francesca; Pandolfi, Francesco; Pauss, Felicitas; Peruzzi, Marco; Quittnat, Milena; Rebane, Liis; Rossini, Marco; Starodumov, Andrei; Takahashi, Maiko; Theofilatos, Konstantinos; Wallny, Rainer; Weber, Hannsjoerg Artur; Amsler, Claude; Canelli, Maria Florencia; Chiochia, Vincenzo; De Cosa, Annapaola; Hinzmann, Andreas; Hreus, Tomas; Kilminster, Benjamin; Lange, Clemens; Millan Mejias, Barbara; Ngadiuba, Jennifer; Robmann, Peter; Ronga, Frederic Jean; Taroni, Silvia; Verzetti, Mauro; Yang, Yong; Cardaci, Marco; Chen, Kuan-Hsin; Ferro, Cristina; Kuo, Chia-Ming; Lin, Willis; Lu, Yun-Ju; Volpe, Roberta; Yu, Shin-Shan; Chang, Paoti; Chang, You-Hao; Chang, Yu-Wei; Chao, Yuan; Chen, Kai-Feng; Chen, Po-Hsun; Dietz, Charles; Grundler, Ulysses; Hou, George Wei-Shu; Kao, Kai-Yi; Lei, Yeong-Jyi; Liu, Yueh-Feng; Lu, Rong-Shyang; Majumder, Devdatta; Petrakou, Eleni; Tzeng, Yeng-Ming; Wilken, Rachel; Asavapibhop, Burin; Srimanobhas, Norraphat; Suwonjandee, Narumon; Adiguzel, Aytul; Bakirci, Mustafa Numan; Cerci, Salim; Dozen, Candan; Dumanoglu, Isa; Eskut, Eda; Girgis, Semiray; Gokbulut, Gul; Gurpinar, Emine; Hos, Ilknur; Kangal, Evrim Ersin; Kayis Topaksu, Aysel; Onengut, Gulsen; Ozdemir, Kadri; Ozturk, Sertac; Polatoz, Ayse; Sogut, Kenan; Sunar Cerci, Deniz; Tali, Bayram; Topakli, Huseyin; Vergili, Mehmet; Akin, Ilina Vasileva; Bilin, Bugra; Bilmis, Selcuk; Gamsizkan, Halil; Karapinar, Guler; Ocalan, Kadir; Sekmen, Sezen; Surat, Ugur Emrah; Yalvac, Metin; Zeyrek, Mehmet; Gülmez, Erhan; Isildak, Bora; Kaya, Mithat; Kaya, Ozlem; Bahtiyar, Hüseyin; Barlas, Esra; Cankocak, Kerem; Vardarli, Fuat Ilkehan; Yücel, Mete; Levchuk, Leonid; Sorokin, Pavel; Brooke, James John; Clement, Emyr; Cussans, David; Flacher, Henning; Frazier, Robert; Goldstein, Joel; Grimes, Mark; Heath, Greg P; Heath, Helen F; Jacob, Jeson; Kreczko, Lukasz; Lucas, Chris; Meng, Zhaoxia; Newbold, Dave M; Paramesvaran, Sudarshan; Poll, Anthony; Senkin, Sergey; Smith, Vincent J; Williams, Thomas; Bell, Ken W; Belyaev, Alexander; Brew, Christopher; Brown, Robert M; Cockerill, David JA; Coughlan, John A; Harder, Kristian; Harper, Sam; Olaiya, Emmanuel; Petyt, David; Shepherd-Themistocleous, Claire; Thea, Alessandro; Tomalin, Ian R; Womersley, William John; Worm, Steven; Baber, Mark; Bainbridge, Robert; Buchmuller, Oliver; Burton, Darren; Colling, David; Cripps, Nicholas; Cutajar, Michael; Dauncey, Paul; Davies, Gavin; Della Negra, Michel; Dunne, Patrick; Ferguson, William; Fulcher, Jonathan; Futyan, David; Gilbert, Andrew; Hall, Geoffrey; Iles, Gregory; Jarvis, Martyn; Karapostoli, Georgia; Kenzie, Matthew; Lane, Rebecca; Lucas, Robyn; Lyons, Louis; Magnan, Anne-Marie; Malik, Sarah; Mathias, Bryn; Nash, Jordan; Nikitenko, Alexander; Pela, Joao; Pesaresi, Mark; Petridis, Konstantinos; Raymond, David Mark; Rogerson, Samuel; Rose, Andrew; Seez, Christopher; Sharp, Peter; Tapper, Alexander; Vazquez Acosta, Monica; Virdee, Tejinder; Cole, Joanne; Hobson, Peter R; Khan, Akram; Kyberd, Paul; Leggat, Duncan; Leslie, Dawn; Martin, William; Reid, Ivan; Symonds, Philip; Teodorescu, Liliana; Turner, Mark; Dittmann, Jay; Hatakeyama, Kenichi; Kasmi, Azeddine; Liu, Hongxuan; Scarborough, Tara; Charaf, Otman; Cooper, Seth; Henderson, Conor; Rumerio, Paolo; Avetisyan, Aram; Bose, Tulika; Fantasia, Cory; Lawson, Philip; Richardson, Clint; Rohlf, James; Sperka, David; St John, Jason; Sulak, Lawrence; Alimena, Juliette; Berry, Edmund; Bhattacharya, Saptaparna; Christopher, Grant; Cutts, David; Demiragli, Zeynep; Ferapontov, Alexey; Garabedian, Alex; Heintz, Ulrich; Kukartsev, Gennadiy; Laird, Edward; Landsberg, Greg; Luk, Michael; Narain, Meenakshi; Segala, Michael; Sinthuprasith, Tutanon; Speer, Thomas; Swanson, Joshua; Breedon, Richard; Breto, Guillermo; Calderon De La Barca Sanchez, Manuel; Chauhan, Sushil; Chertok, Maxwell; Conway, John; Conway, Rylan; Cox, Peter Timothy; Erbacher, Robin; Gardner, Michael; Ko, Winston; Lander, Richard; Miceli, Tia; Mulhearn, Michael; Pellett, Dave; Pilot, Justin; Ricci-Tam, Francesca; Searle, Matthew; Shalhout, Shalhout; Smith, John; Squires, Michael; Stolp, Dustin; Tripathi, Mani; Wilbur, Scott; Yohay, Rachel; Cousins, Robert; Everaerts, Pieter; Farrell, Chris; Hauser, Jay; Ignatenko, Mikhail; Rakness, Gregory; Takasugi, Eric; Valuev, Vyacheslav; Weber, Matthias; Babb, John; Burt, Kira; Clare, Robert; Ellison, John Anthony; Gary, J William; Hanson, Gail; Heilman, Jesse; Ivova Rikova, Mirena; Jandir, Pawandeep; Kennedy, Elizabeth; Lacroix, Florent; Liu, Hongliang; Long, Owen Rosser; Luthra, Arun; Malberti, Martina; Nguyen, Harold; Olmedo Negrete, Manuel; Shrinivas, Amithabh; Sumowidagdo, Suharyo; Wimpenny, Stephen; Andrews, Warren; Branson, James G; Cerati, Giuseppe Benedetto; Cittolin, Sergio; D'Agnolo, Raffaele Tito; Evans, David; Holzner, André; Kelley, Ryan; Klein, Daniel; Lebourgeois, Matthew; Letts, James; Macneill, Ian; Olivito, Dominick; Padhi, Sanjay; Palmer, Christopher; Pieri, Marco; Sani, Matteo; Sharma, Vivek; Simon, Sean; Sudano, Elizabeth; Tadel, Matevz; Tu, Yanjun; Vartak, Adish; Welke, Charles; Würthwein, Frank; Yagil, Avraham; Yoo, Jaehyeok; Barge, Derek; Bradmiller-Feld, John; Campagnari, Claudio; Danielson, Thomas; Dishaw, Adam; Flowers, Kristen; Franco Sevilla, Manuel; Geffert, Paul; George, Christopher; Golf, Frank; Gouskos, Loukas; Incandela, Joe; Justus, Christopher; Mccoll, Nickolas; Richman, Jeffrey; Stuart, David; To, Wing; West, Christopher; Apresyan, Artur; Bornheim, Adolf; Bunn, Julian; Chen, Yi; Di Marco, Emanuele; Duarte, Javier; Mott, Alexander; Newman, Harvey B; Pena, Cristian; Rogan, Christopher; Spiropulu, Maria; Timciuc, Vladlen; Wilkinson, Richard; Xie, Si; Zhu, Ren-Yuan; Azzolini, Virginia; Calamba, Aristotle; Carlson, Benjamin; Ferguson, Thomas; Iiyama, Yutaro; Paulini, Manfred; Russ, James; Vogel, Helmut; Vorobiev, Igor; Cumalat, John Perry; Ford, William T; Gaz, Alessandro; Luiggi Lopez, Eduardo; Nauenberg, Uriel; Smith, James; Stenson, Kevin; Ulmer, Keith; Wagner, Stephen Robert; Alexander, James; Chatterjee, Avishek; Chu, Jennifer; Dittmer, Susan; Eggert, Nicholas; Mirman, Nathan; Nicolas Kaufman, Gala; Patterson, Juliet Ritchie; Ryd, Anders; Salvati, Emmanuele; Skinnari, Louise; Sun, Werner; Teo, Wee Don; Thom, Julia; Thompson, Joshua; Tucker, Jordan; Weng, Yao; Winstrom, Lucas; Wittich, Peter; Winn, Dave; Abdullin, Salavat; Albrow, Michael; Anderson, Jacob; Apollinari, Giorgio; Bauerdick, Lothar AT; Beretvas, Andrew; Berryhill, Jeffrey; Bhat, Pushpalatha C; Burkett, Kevin; Butler, Joel Nathan; Cheung, Harry; Chlebana, Frank; Cihangir, Selcuk; Elvira, Victor Daniel; Fisk, Ian; Freeman, Jim; Gao, Yanyan; Gottschalk, Erik; Gray, Lindsey; Green, Dan; Grünendahl, Stefan; Gutsche, Oliver; Hanlon, Jim; Hare, Daryl; Harris, Robert M; Hirschauer, James; Hooberman, Benjamin; Jindariani, Sergo; Johnson, Marvin; Joshi, Umesh; Kaadze, Ketino; Klima, Boaz; Kreis, Benjamin; Kwan, Simon; Linacre, Jacob; Lincoln, Don; Lipton, Ron; Liu, Tiehui; Lykken, Joseph; Maeshima, Kaori; Marraffino, John Michael; Martinez Outschoorn, Verena Ingrid; Maruyama, Sho; Mason, David; McBride, Patricia; Mishra, Kalanand; Mrenna, Stephen; Musienko, Yuri; Nahn, Steve; Newman-Holmes, Catherine; O'Dell, Vivian; Prokofyev, Oleg; Sexton-Kennedy, Elizabeth; Sharma, Seema; Soha, Aron; Spalding, William J; Spiegel, Leonard; Taylor, Lucas; Tkaczyk, Slawek; Tran, Nhan Viet; Uplegger, Lorenzo; Vaandering, Eric Wayne; Vidal, Richard; Whitbeck, Andrew; Whitmore, Juliana; Yang, Fan; Acosta, Darin; Avery, Paul; Bourilkov, Dimitri; Carver, Matthew; Cheng, Tongguang; Curry, David; Das, Souvik; De Gruttola, Michele; Di Giovanni, Gian Piero; Field, Richard D; Fisher, Matthew; Furic, Ivan-Kresimir; Hugon, Justin; Konigsberg, Jacobo; Korytov, Andrey; Kypreos, Theodore; Low, Jia Fu; Matchev, Konstantin; Milenovic, Predrag; Mitselmakher, Guenakh; Muniz, Lana; Rinkevicius, Aurelijus; Shchutska, Lesya; Snowball, Matthew; Yelton, John; Zakaria, Mohammed; Hewamanage, Samantha; Linn, Stephan; Markowitz, Pete; Martinez, German; Rodriguez, Jorge Luis; Adams, Todd; Askew, Andrew; Bochenek, Joseph; Diamond, Brendan; Haas, Jeff; Hagopian, Sharon; Hagopian, Vasken; Johnson, Kurtis F; Prosper, Harrison; Veeraraghavan, Venkatesh; Weinberg, Marc; Baarmand, Marc M; Hohlmann, Marcus; Kalakhety, Himali; Yumiceva, Francisco; Adams, Mark Raymond; Apanasevich, Leonard; Bazterra, Victor Eduardo; Berry, Douglas; Betts, Russell Richard; Bucinskaite, Inga; Cavanaugh, Richard; Evdokimov, Olga; Gauthier, Lucie; Gerber, Cecilia Elena; Hofman, David Jonathan; Khalatyan, Samvel; Kurt, Pelin; Moon, Dong Ho; O'Brien, Christine; Silkworth, Christopher; Turner, Paul; Varelas, Nikos; Albayrak, Elif Asli; Bilki, Burak; Clarida, Warren; Dilsiz, Kamuran; Duru, Firdevs; Haytmyradov, Maksat; Merlo, Jean-Pierre; Mermerkaya, Hamit; Mestvirishvili, Alexi; Moeller, Anthony; Nachtman, Jane; Ogul, Hasan; Onel, Yasar; Ozok, Ferhat; Penzo, Aldo; Rahmat, Rahmat; Sen, Sercan; Tan, Ping; Tiras, Emrah; Wetzel, James; Yetkin, Taylan; Yi, Kai; Barnett, Bruce Arnold; Blumenfeld, Barry; Bolognesi, Sara; Fehling, David; Gritsan, Andrei; Maksimovic, Petar; Martin, Christopher; Swartz, Morris; Baringer, Philip; Bean, Alice; Benelli, Gabriele; Bruner, Christopher; Gray, Julia; Kenny III, Raymond Patrick; Malek, Magdalena; Murray, Michael; Noonan, Daniel; Sanders, Stephen; Sekaric, Jadranka; Stringer, Robert; Wang, Quan; Wood, Jeffrey Scott; Barfuss, Anne-Fleur; Chakaberia, Irakli; Ivanov, Andrew; Khalil, Sadia; Makouski, Mikhail; Maravin, Yurii; Saini, Lovedeep Kaur; Shrestha, Shruti; Skhirtladze, Nikoloz; Svintradze, Irakli; Gronberg, Jeffrey; Lange, David; Rebassoo, Finn; Wright, Douglas; Baden, Drew; Belloni, Alberto; Calvert, Brian; Eno, Sarah Catherine; Gomez, Jaime; Hadley, Nicholas John; Kellogg, Richard G; Kolberg, Ted; Lu, Ying; Marionneau, Matthieu; Mignerey, Alice; Pedro, Kevin; Skuja, Andris; Tonjes, Marguerite; Tonwar, Suresh C; Apyan, Aram; Barbieri, Richard; Bauer, Gerry; Busza, Wit; Cali, Ivan Amos; Chan, Matthew; Di Matteo, Leonardo; Dutta, Valentina; Gomez Ceballos, Guillelmo; Goncharov, Maxim; Gulhan, Doga; Klute, Markus; Lai, Yue Shi; Lee, Yen-Jie; Levin, Andrew; Luckey, Paul David; Ma, Teng; Paus, Christoph; Ralph, Duncan; Roland, Christof; Roland, Gunther; Stephans, George; Stöckli, Fabian; Sumorok, Konstanty; Velicanu, Dragos; Veverka, Jan; Wyslouch, Bolek; Yang, Mingming; Zanetti, Marco; Zhukova, Victoria; Dahmes, Bryan; Gude, Alexander; Kao, Shih-Chuan; Klapoetke, Kevin; Kubota, Yuichi; Mans, Jeremy; Pastika, Nathaniel; Rusack, Roger; Singovsky, Alexander; Tambe, Norbert; Turkewitz, Jared; Acosta, John Gabriel; Oliveros, Sandra; Avdeeva, Ekaterina; Bloom, Kenneth; Bose, Suvadeep; Claes, Daniel R; Dominguez, Aaron; Gonzalez Suarez, Rebeca; Keller, Jason; Knowlton, Dan; Kravchenko, Ilya; Lazo-Flores, Jose; Malik, Sudhir; Meier, Frank; Snow, Gregory R; Dolen, James; Godshalk, Andrew; Iashvili, Ia; Kharchilava, Avto; Kumar, Ashish; Rappoccio, Salvatore; Alverson, George; Barberis, Emanuela; Baumgartel, Darin; Chasco, Matthew; Haley, Joseph; Massironi, Andrea; Morse, David Michael; Nash, David; Orimoto, Toyoko; Trocino, Daniele; Wang, Ren-Jie; Wood, Darien; Zhang, Jinzhong; Hahn, Kristan Allan; Kubik, Andrew; Mucia, Nicholas; Odell, Nathaniel; Pollack, Brian; Pozdnyakov, Andrey; Schmitt, Michael Henry; Stoynev, Stoyan; Sung, Kevin; Velasco, Mayda; Won, Steven; Brinkerhoff, Andrew; Chan, Kwok Ming; Drozdetskiy, Alexey; Hildreth, Michael; Jessop, Colin; Karmgard, Daniel John; Kellams, Nathan; Lannon, Kevin; Luo, Wuming; Lynch, Sean; Marinelli, Nancy; Pearson, Tessa; Planer, Michael; Ruchti, Randy; Valls, Nil; Wayne, Mitchell; Wolf, Matthias; Woodard, Anna; Antonelli, Louis; Brinson, Jessica; Bylsma, Ben; Durkin, Lloyd Stanley; Flowers, Sean; Hill, Christopher; Hughes, Richard; Kotov, Khristian; Ling, Ta-Yung; Puigh, Darren; Rodenburg, Marissa; Smith, Geoffrey; Winer, Brian L; Wolfe, Homer; Wulsin, Howard Wells; Driga, Olga; Elmer, Peter; Hebda, Philip; Hunt, Adam; Koay, Sue Ann; Lujan, Paul; Marlow, Daniel; Medvedeva, Tatiana; Mooney, Michael; Olsen, James; Piroué, Pierre; Quan, Xiaohang; Saka, Halil; Stickland, David; Tully, Christopher; Werner, Jeremy Scott; Zenz, Seth Conrad; Zuranski, Andrzej; Brownson, Eric; Mendez, Hector; Ramirez Vargas, Juan Eduardo; Barnes, Virgil E; Benedetti, Daniele; Bolla, Gino; Bortoletto, Daniela; De Mattia, Marco; Hu, Zhen; Jha, Manoj; Jones, Matthew; Jung, Kurt; Kress, Matthew; Leonardo, Nuno; Lopes Pegna, David; Maroussov, Vassili; Merkel, Petra; Miller, David Harry; Neumeister, Norbert; Radburn-Smith, Benjamin Charles; Shi, Xin; Shipsey, Ian; Silvers, David; Svyatkovskiy, Alexey; Wang, Fuqiang; Xie, Wei; Xu, Lingshan; Yoo, Hwi Dong; Zablocki, Jakub; Zheng, Yu; Parashar, Neeti; Stupak, John; Adair, Antony; Akgun, Bora; Ecklund, Karl Matthew; Geurts, Frank JM; Li, Wei; Michlin, Benjamin; Padley, Brian Paul; Redjimi, Radia; Roberts, Jay; Zabel, James; Betchart, Burton; Bodek, Arie; Covarelli, Roberto; de Barbaro, Pawel; Demina, Regina; Eshaq, Yossof; Ferbel, Thomas; Garcia-Bellido, Aran; Goldenzweig, Pablo; Han, Jiyeon; Harel, Amnon; Khukhunaishvili, Aleko; Petrillo, Gianluca; Vishnevskiy, Dmitry; Ciesielski, Robert; Demortier, Luc; Goulianos, Konstantin; Lungu, Gheorghe; Mesropian, Christina; Arora, Sanjay; Barker, Anthony; Chou, John Paul; Contreras-Campana, Christian; Contreras-Campana, Emmanuel; Duggan, Daniel; Ferencek, Dinko; Gershtein, Yuri; Gray, Richard; Halkiadakis, Eva; Hidas, Dean; Kaplan, Steven; Lath, Amitabh; Panwalkar, Shruti; Park, Michael; Patel, Rishi; Salur, Sevil; Schnetzer, Steve; Somalwar, Sunil; Stone, Robert; Thomas, Scott; Thomassen, Peter; Walker, Matthew; Rose, Keith; Spanier, Stefan; York, Andrew; Bouhali, Othmane; Castaneda Hernandez, Alfredo; Eusebi, Ricardo; Flanagan, Will; Gilmore, Jason; Kamon, Teruki; Khotilovich, Vadim; Krutelyov, Vyacheslav; Montalvo, Roy; Osipenkov, Ilya; Pakhotin, Yuriy; Perloff, Alexx; Roe, Jeffrey; Rose, Anthony; Safonov, Alexei; Sakuma, Tai; Suarez, Indara; Tatarinov, Aysen; Akchurin, Nural; Cowden, Christopher; Damgov, Jordan; Dragoiu, Cosmin; Dudero, Phillip Russell; Faulkner, James; Kovitanggoon, Kittikul; Kunori, Shuichi; Lee, Sung Won; Libeiro, Terence; Volobouev, Igor; Appelt, Eric; Delannoy, Andrés G; Greene, Senta; Gurrola, Alfredo; Johns, Willard; Maguire, Charles; Mao, Yaxian; Melo, Andrew; Sharma, Monika; Sheldon, Paul; Snook, Benjamin; Tuo, Shengquan; Velkovska, Julia; Arenton, Michael Wayne; Boutle, Sarah; Cox, Bradley; Francis, Brian; Goodell, Joseph; Hirosky, Robert; Ledovskoy, Alexander; Li, Hengne; Lin, Chuanzhe; Neu, Christopher; Wood, John; Clarke, Christopher; Harr, Robert; Karchin, Paul Edmund; Kottachchi Kankanamge Don, Chamath; Lamichhane, Pramod; Sturdy, Jared; Belknap, Donald; Carlsmith, Duncan; Cepeda, Maria; Dasu, Sridhara; Dodd, Laura; Duric, Senka; Friis, Evan; Hall-Wilton, Richard; Herndon, Matthew; Hervé, Alain; Klabbers, Pamela; Lanaro, Armando; Lazaridis, Christos; Levine, Aaron; Loveless, Richard; Mohapatra, Ajit; Ojalvo, Isabel; Perry, Thomas; Pierro, Giuseppe Antonio; Polese, Giovanni; Ross, Ian; Sarangi, Tapas; Savin, Alexander; Smith, Wesley H; Vuosalo, Carl; Woods, Nathaniel

    2015-04-09

    A measurement of the production cross section ratio $\\sigma(\\chi_{b2}(1\\mathrm{P}))/ \\sigma(\\chi_{b1}(1\\mathrm{P}))$ is presented. The $\\chi_{b1}(1\\mathrm{P})$ and $\\chi_{b2}(1\\mathrm{P})$ bottomonium states, promptly produced in pp collisions at $\\sqrt{s}$= 8 TeV, are detected by the CMS experiment at the CERN LHC through their radiative decays $\\chi_{b1,2}(1\\mathrm{P}) \\rightarrow \\Upsilon(1\\mathrm{S}) + \\gamma$. The emitted photons are measured through their conversion to e$^+$e$^-$ pairs, whose reconstruction allows the two states to be resolved. The $\\Upsilon(1\\mathrm{S})$ is measured through its decay to two muons. An event sample corresponding to an integrated luminosity of 20.7 fb$^{-1}$ is used to measure the cross section ratio in a phase-space region defined by the photon pseudorapidity, |$\\eta^\\gamma$| < 1.0; the $\\Upsilon(1\\mathrm{S})$ rapidity, |$y^\\Upsilon$| < 1.5; and the $\\Upsilon(1\\mathrm{S})$ transverse momentum, 7 < $p_{\\mathrm{T}}^\\Upsilon$ < 40 GeV. The cross section ratio sh...

  11. Two-phase flow instrumentation and laser beams

    International Nuclear Information System (INIS)

    Delhaye, J.M.

    1976-01-01

    Some methods based on laser techniques in order to place emphasis on the relation between measured quantities and the primary variables entering the general equations of two-phase systems are reviewed and summarized. The case where the bubbles or droplets are so small that they act as individual scattering centers is excluded [fr

  12. Resonance phase and sings of P-odd and P-even effects, observable in the reactions with neutrons

    International Nuclear Information System (INIS)

    Smotritskij, L.M.

    2002-01-01

    It is shown that introduction of the resonance phase for two quasistationary states with a similar spin and counter parity makes it possible to correlate the sing dependence of both the P-odd and P-even effects, experimentally observed in the reactions with neutrons. The common description of such effects enables determination of the theory unknown (free) parameters from the experiment [ru

  13. Design and construction of an experiment for two-phase flow in fractured porous media

    Energy Technology Data Exchange (ETDEWEB)

    Ayala, R.E.G.; Aziz, K.

    1993-08-01

    In numerical reservoir simulation naturally fractured reservoirs are commonly divided into matrix and fracture systems. The high permeability fractures are usually entirely responsible for flow between blocks and flow to the wells. The flow in these fractures is modeled using Darcy`s law and its extension to multiphase flow by means of relative permeabilities. The influence and measurement of fracture relative permeability for two-phase flow in fractured porous media have not been studied extensively, and the few works presented in the literature are contradictory. Experimental and numerical work on two-phase flow in fractured porous media has been initiated. An apparatus for monitoring this type of flow was designed and constructed. It consists of an artificially fractured core inside an epoxy core holder, detailed pressure and effluent monitoring, saturation measurements by means of a CT-scanner and a computerized data acquisition system. The complete apparatus was assembled and tested at conditions similar to the conditions expected for the two-phase flow experiments. Fine grid simulations of the experimental setup-were performed in order to establish experimental conditions and to study the effects of several key variables. These variables include fracture relative permeability and fracture capillary pressure. The numerical computations show that the flow is dominated by capillary imbibition, and that fracture relative permeabilities have only a minor influence. High oil recoveries without water production are achieved due to effective water imbibition from the fracture to the matrix. When imbibition is absent, fracture relative permeabilities affect the flow behavior at early production times.

  14. Variation in pH of Model Secondary Organic Aerosol during Liquid-Liquid Phase Separation.

    Science.gov (United States)

    Dallemagne, Magda A; Huang, Xiau Ya; Eddingsaas, Nathan C

    2016-05-12

    The majority of atmospheric aerosols consist of both organic and inorganic components. At intermediate relative humidity (RH), atmospheric aerosol can undergo liquid-liquid phase separation (LLPS) in which the organic and inorganic fractions segregate from each other. We have extended the study of LLPS to the effect that phase separation has on the pH of the overall aerosols and the pH of the individual phases. Using confocal microscopy and pH sensitive dyes, the pH of internally mixed model aerosols consisting of polyethylene glycol 400 and ammonium sulfate as well as the pH of the organic fraction during LLPS have been directly measured. During LLPS, the pH of the organic fraction was observed to increase to 4.2 ± 0.2 from 3.8 ± 0.1 under high RH when the aerosol was internally mixed. In addition, the high spatial resolution of the confocal microscope allowed us to characterize the composition of each of the phases, and we have observed that during LLPS the organic shell still contains large quantities of water and should be characterized as an aqueous organic-rich phase rather than simply an organic phase.

  15. Estimating disease prevalence from two-phase surveys with non-response at the second phase

    Science.gov (United States)

    Gao, Sujuan; Hui, Siu L.; Hall, Kathleen S.; Hendrie, Hugh C.

    2010-01-01

    SUMMARY In this paper we compare several methods for estimating population disease prevalence from data collected by two-phase sampling when there is non-response at the second phase. The traditional weighting type estimator requires the missing completely at random assumption and may yield biased estimates if the assumption does not hold. We review two approaches and propose one new approach to adjust for non-response assuming that the non-response depends on a set of covariates collected at the first phase: an adjusted weighting type estimator using estimated response probability from a response model; a modelling type estimator using predicted disease probability from a disease model; and a regression type estimator combining the adjusted weighting type estimator and the modelling type estimator. These estimators are illustrated using data from an Alzheimer’s disease study in two populations. Simulation results are presented to investigate the performances of the proposed estimators under various situations. PMID:10931514

  16. Environment-related properties of polyhydroxylated dibenzo-p-dioxins

    Energy Technology Data Exchange (ETDEWEB)

    Shi, Jia-Qi; Qu, Rui-juan [State Key Laboratory of Pollution Control and Resources Reuse, School of the Environment, Xianlin Campus, Nanjing University, Nanjing 210046 (China); Flamm, Alison [U.S. Fulbright Student Grantee, School of Social and Behavioral Sciences, Nanjing University, Nanjing 210093 (China); Liu, Hong-Xia [School of Biological and Chemical Engineering, Jiaxing University, Jiaxing 314001 (China); Xu, Ying [State Key Laboratory of Pollution Control and Resources Reuse, School of the Environment, Xianlin Campus, Nanjing University, Nanjing 210046 (China); Wang, Zun-Yao, E-mail: wangzun315cn@163.com [State Key Laboratory of Pollution Control and Resources Reuse, School of the Environment, Xianlin Campus, Nanjing University, Nanjing 210046 (China)

    2012-01-01

    Polyhydroxylated dibenzo-p-dioxins (PHODDs) are important metabolic and synthetic products of polychlorinated dibenzo-p-dioxins (PCDDs). Two types of hydrogen bonds exist in PHODD molecules: one between a hydroxyl group (HO) and an oxygen atom of the ether bond, and the other between two ortho hydroxyls of a benzene ring. By fully optimized calculation with density functional theory (DFT), their bond energies were ascertained to be approximately 9-14 kJ/mol and 15-19 kJ/mol respectively by the comparison of standard Gibbs energy of formation ({Delta}{sub f}G{sup {theta}}) between different molecules, which was experimentally verified. The two types of hydrogen bonds affect the hydrophilicity and stability of the molecules. The torsional potential of hydroxyls and the orientation making the congener most stable were obtained. The octanol-water partition coefficients (logK{sub ow}s) were calculated based on the group contribution method, and the standard state entropy (S{sup {theta}}), standard enthalpy ({Delta}{sub f}H{sup {theta}}) of formation and {Delta}{sub f}G{sup {theta}} were obtained from the combination of DFT calculation and isodesmic reaction for the stable PHODD congeners. The number and position of hydroxyl substitution (N{sub PHOS}) were employed as descriptors to establish quantitative structure-property relationship (QSPR) models. Although the hydrophilicity of PHODDs increases with the number of hydroxyl groups, it is impaired by the intramolecular hydrogen bonds. The logK{sub ow}s of PHODDs are much smaller than those of PCDDs, and the variation trend with the number of substituents is different. In addition, the relative stability order of PHODD congeners was theoretically proposed, which is quite different from that of PCDDs. Considering the ionization in water, first-order ionization constants of PHODDs were calculated according to the results of SMD method of Self-Consistent Reaction Field Theory (SCRF), and they were influenced by the hydrogen

  17. Predicting a new phase (T'') of two-dimensional transition metal di-chalcogenides and strain-controlled topological phase transition

    Science.gov (United States)

    Ma, Fengxian; Gao, Guoping; Jiao, Yalong; Gu, Yuantong; Bilic, Ante; Zhang, Haijun; Chen, Zhongfang; Du, Aijun

    2016-02-01

    Single layered transition metal dichalcogenides have attracted tremendous research interest due to their structural phase diversities. By using a global optimization approach, we have discovered a new phase of transition metal dichalcogenides (labelled as T''), which is confirmed to be energetically, dynamically and kinetically stable by our first-principles calculations. The new T'' MoS2 phase exhibits an intrinsic quantum spin Hall (QSH) effect with a nontrivial gap as large as 0.42 eV, suggesting that a two-dimensional (2D) topological insulator can be achieved at room temperature. Most interestingly, there is a topological phase transition simply driven by a small tensile strain of up to 2%. Furthermore, all the known MX2 (M = Mo or W; X = S, Se or Te) monolayers in the new T'' phase unambiguously display similar band topologies and strain controlled topological phase transitions. Our findings greatly enrich the 2D families of transition metal dichalcogenides and offer a feasible way to control the electronic states of 2D topological insulators for the fabrication of high-speed spintronics devices.Single layered transition metal dichalcogenides have attracted tremendous research interest due to their structural phase diversities. By using a global optimization approach, we have discovered a new phase of transition metal dichalcogenides (labelled as T''), which is confirmed to be energetically, dynamically and kinetically stable by our first-principles calculations. The new T'' MoS2 phase exhibits an intrinsic quantum spin Hall (QSH) effect with a nontrivial gap as large as 0.42 eV, suggesting that a two-dimensional (2D) topological insulator can be achieved at room temperature. Most interestingly, there is a topological phase transition simply driven by a small tensile strain of up to 2%. Furthermore, all the known MX2 (M = Mo or W; X = S, Se or Te) monolayers in the new T'' phase unambiguously display similar band topologies and strain controlled topological

  18. Measurements of (p,γ) resonance strengths in the s-d shell

    NARCIS (Netherlands)

    Engelbertink, G.A.P.; Endt, P.M.

    1966-01-01

    Resonace strengths of selected resonances in the Ep=0.3−2.1 MeV region in the (p, γ) reactions on 23Na, 24–24Mg, 27Al, 28–30Si, 31P, 32, 34S, 35, 37Cl, 39, 41K and 40Ca are compared through relative yield measurements, using targets of many different chemical compounds, each containing at least two

  19. Prognostic value of lymphoma-specific S-phase fraction compared with that of other cell proliferation markers

    International Nuclear Information System (INIS)

    Holte, H.; Kvaloey, S.; Suo Zhenhe; Langholm, R.; Smeland, E.B.; Stokke, T.

    1999-01-01

    The proliferation-associated antigens Ki67 (immunohistochemistry) and proliferative cell nuclear antigen (PCNA) (immunohistochemistry and immunoblotting) were analysed together with DNA synthesis ( 3 H-thymidine incorporation) and cell-cycle distribution (tumour-specific S-phase fraction determined by flow cytometry) in lymph node suspensions from 63 patients with newly diagnosed B-Cell non-Hodgkin's lymphomas. Details of clinical parameters, treatment and patient outcome were available for all patients, and retrospectively analysed. Of the proliferation-associated parameters, only high S-phase fraction (p < 0.00001) and high PCNA expression by immunoblotting (p=0.012) were predictive of a poor prognosis. Of the conventional parameters, high-grade malignancy, high International Prognostic Index (IPI) score, bulky disease and presence of B symptoms predicted a patient for poor survival. High S-phase fraction was predictive of a short survival for the low-grade lymphomas analyses separately (p < 0.00001), as well as for patients treated with an Adriamycin- and a non-Adriamycin-containing regimen (p < 0.005 for both groups). In a multivariate analysis, S-phase fraction (p=0.00006), IPI score (p=0.015) and B symptoms (p=0.017) had independent prognostic values, but not histological grade. (orig.)

  20. Regulation of human cerebro-microvascular endothelial baso-lateral adhesion and barrier function by S1P through dual involvement of S1P1 and S1P2 receptors.

    Science.gov (United States)

    Wiltshire, Rachael; Nelson, Vicky; Kho, Dan Ting; Angel, Catherine E; O'Carroll, Simon J; Graham, E Scott

    2016-01-27

    Herein we show that S1P rapidly and acutely reduces the focal adhesion strength and barrier tightness of brain endothelial cells. xCELLigence biosensor technology was used to measure focal adhesion, which was reduced by S1P acutely and this response was mediated through both S1P1 and S1P2 receptors. S1P increased secretion of several pro-inflammatory mediators from brain endothelial cells. However, the magnitude of this response was small in comparison to that mediated by TNFα or IL-1β. Furthermore, S1P did not significantly increase cell-surface expression of any key cell adhesion molecules involved in leukocyte recruitment, included ICAM-1 and VCAM-1. Finally, we reveal that S1P acutely and dynamically regulates microvascular endothelial barrier tightness in a manner consistent with regulated rapid opening followed by closing and strengthening of the barrier. We hypothesise that the role of the S1P receptors in this process is not to cause barrier dysfunction, but is related to controlled opening of the endothelial junctions. This was revealed using real-time measurement of barrier integrity using ECIS ZΘ TEER technology and endothelial viability using xCELLigence technology. Finally, we show that these responses do not occur simply though the pharmacology of a single S1P receptor but involves coordinated action of S1P1 and S1P2 receptors.

  1. P stabilizes dark matter and with CP can predict leptonic phases

    Energy Technology Data Exchange (ETDEWEB)

    Kuchimanchi, Ravi

    2014-02-15

    We find that spontaneously broken parity (P) or left-right symmetry stabilizes darkmatter in a beautiful way. If dark matter has a non-real intrinsic parity ±i (e.g. if it entails Majorana fermions), parity can ensure that it cannot decay to all normal particles with real intrinsic parities. However, if Majorana couplings are absent either in the lepton or the dark sector, P symmetry can be redefined to remove relative non-real intrinsic phases. It is therefore predicted that neutrinos and dark matter fermions must have Majorana masses if dark matter is stable due to parity. The strong CP problem is solved by additionally imposing CP and including vectorlike fermions that help generate CP violation. If leptonlike heavy fermions are provided purely imaginary intrinsic parity phase, they do not couple to the usual leptons, and leptonic CP phases are not generated, which is a testable prediction. Experimentally if leptonic CP phases are not found (if they are consistent with 0 or π) it can be evidence for the type of models in this work where CP is spontaneously or softly broken and there is also a second hidden or softly broken symmetry such as P, Z{sub 2} or Z{sub 4}. However, leptonic CP violation can be present in closely related or some nonminimal versions of these models, such as by also including vectorlike leptons with real intrinsic parities. (orig.)

  2. Two Dimensional Symmetric Correlation Functions of the S Operator and Two Dimensional Fourier Transforms: Considering the Line Coupling for P and R Lines of Linear Molecules

    Science.gov (United States)

    Ma, Q.; Boulet, C.; Tipping, R. H.

    2014-01-01

    The refinement of the Robert-Bonamy (RB) formalism by considering the line coupling for isotropic Raman Q lines of linear molecules developed in our previous study [Q. Ma, C. Boulet, and R. H. Tipping, J. Chem. Phys. 139, 034305 (2013)] has been extended to infrared P and R lines. In these calculations, the main task is to derive diagonal and off-diagonal matrix elements of the Liouville operator iS1 - S2 introduced in the formalism. When one considers the line coupling for isotropic Raman Q lines where their initial and final rotational quantum numbers are identical, the derivations of off-diagonal elements do not require extra correlation functions of the ^S operator and their Fourier transforms except for those used in deriving diagonal elements. In contrast, the derivations for infrared P and R lines become more difficult because they require a lot of new correlation functions and their Fourier transforms. By introducing two dimensional correlation functions labeled by two tensor ranks and making variable changes to become even functions, the derivations only require the latters' two dimensional Fourier transforms evaluated at two modulation frequencies characterizing the averaged energy gap and the frequency detuning between the two coupled transitions. With the coordinate representation, it is easy to accurately derive these two dimensional correlation functions. Meanwhile, by using the sampling theory one is able to effectively evaluate their two dimensional Fourier transforms. Thus, the obstacles in considering the line coupling for P and R lines have been overcome. Numerical calculations have been carried out for the half-widths of both the isotropic Raman Q lines and the infrared P and R lines of C2H2 broadened by N2. In comparison with values derived from the RB formalism, new calculated values are significantly reduced and become closer to measurements.

  3. Phase retrieval from local measurements in two dimensions

    Science.gov (United States)

    Iwen, Mark; Preskitt, Brian; Saab, Rayan; Viswanathan, Aditya

    2017-08-01

    The phase retrieval problem has appeared in a multitude of applications for decades. While ad hoc solutions have existed since the early 1970s, recent developments have provided algorithms that offer promising theoretical guarantees under increasingly realistic assumptions. Motivated by ptychographic imaging, we generalize a recent result on phase retrieval of a one dimensional objective vector x ∈ ℂd to recover a two dimensional sample Q ∈ ℂd x d from phaseless measurements, using a tensor product formulation to extend the previous work.

  4. Apparatus for monitoring two-phase flow

    International Nuclear Information System (INIS)

    Sheppard, J.D.; Tong, L.S.

    1977-01-01

    A method and apparatus for monitoring two-phase flow is provided that is particularly related to the monitoring of transient two-phase (liquid-vapor) flow rates such as may occur during a pressurized water reactor core blow-down. The present invention essentially comprises the use of flanged wire screens or similar devices, such as perforated plates, to produce certain desirable effects in the flow regime for monitoring purposes. One desirable effect is a measurable and reproducible pressure drop across the screen. The pressure drop can be characterized for various known flow rates and then used to monitor nonhomogeneous flow regimes. Another useful effect of the use of screens or plates in nonhomogeneous flow is that such apparatus tends to create a uniformly dispersed flow regime in the immediate downstream vicinity. This is a desirable effect because it usually increases the accuracy of flow rate measurements determined by conventional methods. 3 claims, 9 figures

  5. Microgravity Two-Phase Flow Transition

    Science.gov (United States)

    Parang, M.; Chao, D.

    1999-01-01

    Two-phase flows under microgravity condition find a large number of important applications in fluid handling and storage, and spacecraft thermal management. Specifically, under microgravity condition heat transfer between heat exchanger surfaces and fluids depend critically on the distribution and interaction between different fluid phases which are often qualitatively different from the gravity-based systems. Heat transfer and flow analysis in two-phase flows under these conditions require a clear understanding of the flow pattern transition and development of appropriate dimensionless scales for its modeling and prediction. The physics of this flow is however very complex and remains poorly understood. This has led to various inadequacies in flow and heat transfer modeling and has made prediction of flow transition difficult in engineering design of efficient thermal and flow systems. In the present study the available published data for flow transition under microgravity condition are considered for mapping. The transition from slug to annular flow and from bubbly to slug flow are mapped using dimensionless variable combination developed in a previous study by the authors. The result indicate that the new maps describe the flow transitions reasonably well over the range of the data available. The transition maps are examined and the results are discussed in relation to the presumed balance of forces and flow dynamics. It is suggested that further evaluation of the proposed flow and transition mapping will require a wider range of microgravity data expected to be made available in future studies.

  6. Heat transfer modelling of two-phase bubbles swarm condensing in three - phase direct - contact condenser

    Directory of Open Access Journals (Sweden)

    Mahood Hameed B.

    2016-01-01

    Full Text Available An analytical model for the convective heat transfer coefficient and the two-phase bubble size of a three-phase direct contact heat exchanger was developed. Until the present, there has only been a theoretical model available that deals with a single two-phase bubble and a bubble train condensation in an immiscible liquid. However, to understand the actual heat transfer process within the three-phase direct contact condenser, characteristic models are required. A quasi - steady energy equation in a spherical coordinate system with a potential flow assumption and a cell model configuration has been simplified and solved analytically. The convective heat transfer in terms of Nu number has been derived, and it was found to be a function to Pe number and a system void fraction. In addition, the two-phase bubble size relates to the system void fraction and has been developed by solving a simple energy balance equation and using the derived convective heat transfer coefficient expression. Furthermore, the model correlates well with previous experimental data and theoretical results.

  7. Unified pH values of liquid chromatography mobile phases.

    Science.gov (United States)

    Suu, Agnes; Jalukse, Lauri; Liigand, Jaanus; Kruve, Anneli; Himmel, Daniel; Krossing, Ingo; Rosés, Martí; Leito, Ivo

    2015-03-03

    This work introduces a conceptually new approach of measuring pH of mixed-solvent liquid chromatography (LC) mobile phases. Mobile phase pH is very important in LC, but its correct measurement is not straightforward, and all commonly used approaches have deficiencies. The new approach is based on the recently introduced unified pH (pH(abs)) scale, which enables direct comparison of acidities of solutions made in different solvents based on chemical potential of the proton in the solutions. This work represents the first experimental realization of the pH(abs) concept using differential potentiometric measurement for comparison of the chemical potentials of the proton in different solutions (connected by a salt bridge), together with earlier published reference points for obtaining the pH(abs) values (referenced to the gas phase) or pH(abs)(H₂O) values (referenced to the aqueous solution). The liquid junction potentials were estimated in the framework of Izutsu's three-component method. pH(abs) values for a number of common LC and LC-MS mobile phases have been determined. The pH(abs) scale enables for the first time direct comparison of acidities of any LC mobile phases, with different organic additives, different buffer components, etc. A possible experimental protocol of putting this new approach into chromatographic practice has been envisaged and its applicability tested. It has been demonstrated that the ionization behavior of bases (cationic acids) in the mobile phases can be better predicted by using the pH(abs)(H₂O) values and aqueous pKa values than by using the alternative means of expressing mobile phase acidity. Description of the ionization behavior of acids on the basis of pH(abs)(H₂O) values is possible if the change of their pKa values with solvent composition change is taken into account.

  8. Phase relations in the quasi-binary Cu{sub 2}GeS{sub 3}-ZnS and quasi-ternary Cu{sub 2}S-Zn(Cd)S-GeS{sub 2} systems and crystal structure of Cu{sub 2}ZnGeS{sub 4}

    Energy Technology Data Exchange (ETDEWEB)

    Parasyuk, O.V. [Department of General and Inorganic Chemistry, Volyn State University, Voli Ave 13, 43009 Lutsk (Ukraine)]. E-mail: oleg@lab.univer.lutsk.ua; Piskach, L.V. [Department of General and Inorganic Chemistry, Volyn State University, Voli Ave 13, 43009 Lutsk (Ukraine); Romanyuk, Y.E. [Advanced Photonics Laboratory, Institute of Imaging and Applied Optics, Ecole Polytechnique Federale de Lausanne, CH-1015 Lausanne (Switzerland); Olekseyuk, I.D. [Department of General and Inorganic Chemistry, Volyn State University, Voli Ave 13, 43009 Lutsk (Ukraine); Zaremba, V.I. [Department of Inorganic Chemistry, Ivan Franko National University of Lviv, 6 Kyryla and Mefodiya Str., 79005 L' viv (Ukraine); Pekhnyo, V.I. [V.I. Vernadskii Institute of General and Inorganic Chemistry, Ukrainian National Academy of Sciences, Palladina Ave 32-34, 03680 Kiev (Ukraine)

    2005-07-19

    The isothermal section of the Cu{sub 2}S-Zn(Cd)S-GeS{sub 2} systems at 670K was constructed using X-ray diffraction analysis. At this temperature, two quaternary intermediate phases, Cu{sub 2}CdGeS{sub 4} and {approx}Cu{sub 8}CdGeS{sub 7}, exist in the Cu{sub 2}S-CdS-GeS{sub 2} system, and only one phase, Cu{sub 2}ZnGeS{sub 4}, exists in the Cu{sub 2}S-ZnS-GeS{sub 2} system. The phase diagram of the Cu{sub 2}GeS{sub 3}-ZnS system was constructed using differential-thermal analysis and X-ray diffraction, and the existence of Cu{sub 2}ZnGeS{sub 4} has been confirmed. It forms incongruently at 1359K. Powder X-ray diffraction was used to refine the crystal structure of Cu{sub 2}ZnGeS{sub 4}, which crystallizes in the tetragonal stannite-type structure at 670K (space group I4-bar 2m, a=0.534127(9)nm, c=1.05090(2)nm, R{sub I}=0.0477). The possibility of the formation of quaternary compounds in the quasi-ternary systems A{sup I}{sub 2}X-B{sup II}X-C{sup IV}X{sub 2}, where A{sup I}-Cu, Ag; B{sup II}-Zn, Cd, Hg; C{sup IV}-Si, Ge, Sn and X-S, Se, Te is discussed.

  9. Experiments in polydisperse two-phase turbulent flows

    International Nuclear Information System (INIS)

    Bachalo, W.D.; Houser, M.J.

    1985-01-01

    Aspects of turbulent two-phase flow measurements obtained with a laser Doppler velocimeter that was modified to also obtain particle size were investigated. Simultaneous measurements of the particle size and velocity allowed the determination of the lag characteristics of particles over a range of sizes. Relatively large particles were found to respond well to the turbulent fluctuations in low speed flows. Measurements of sprays were obtained at various points throughout the spray plume. Velocity measurements for each drop size class were obtained and revealed the relative velocity relaxation with downstream distance. The evolution of the rms velocities for each size class was also examined. Difficulties associated with seeding polydispersions to obtain gas phase turbulence data were discussed. Several approaches for mitigating the errors due to seed particle concentration bias were reviewed

  10. Self-organizing maps applied to two-phase flow on natural circulation loop study

    International Nuclear Information System (INIS)

    Castro, Leonardo Ferreira

    2016-01-01

    Two-phase flow of liquid and gas is found in many closed circuits using natural circulation for cooling purposes. Natural circulation phenomenon is important on recent nuclear power plant projects for decay heat removal. The Natural Circulation Facility (Circuito de Circulacao Natural CCN) installed at Instituto de Pesquisas Energeticas e Nucleares, IPEN/CNEN, is an experimental circuit designed to provide thermal hydraulic data related to single and two-phase flow under natural circulation conditions. This periodic flow oscillation behavior can be observed thoroughly in this facility due its glass-made tubes transparency. The heat transfer estimation has been improved based on models that require precise prediction of pattern transitions of flow. This work presents experiments realized at CCN to visualize natural circulation cycles in order to classify two-phase flow patterns associated with phase transients and static instabilities of flow. Images are compared and clustered using Kohonen Self-organizing Maps (SOM's) applied on different digital image features. The Full Frame Discret Cosine Transform (FFDCT) coefficients were used as input for the classification task, enabling good results. FFDCT prototypes obtained can be associated to each flow pattern, enabling a better comprehension of each observed instability. A systematic test methodology was used to verify classifier robustness.

  11. Competing p-wave orders

    International Nuclear Information System (INIS)

    Donos, Aristomenis; Gauntlett, Jerome P; Pantelidou, Christiana

    2014-01-01

    We construct electrically charged, asymptotically AdS 5 black hole solutions that are dual to d = 4 CFTs in a superfluid phase with either p-wave or (p + ip)-wave order. The two types of black holes have non-vanishing charged two-form in the bulk and appear at the same critical temperature in the unbroken phase. Both the p-wave and the (p + ip)-wave phase can be thermodynamically preferred, depending on the mass and charge of the two-form, and there can also be first order transitions between them. The p-wave black holes have a helical structure and some of them exhibit the phenomenon of pitch inversion as the temperature is decreased. Both the p-wave and the (p + ip)-wave black holes have zero entropy density ground states at zero temperature and we identify some new ground states which exhibit scaling symmetry, including a novel scenario for the emergence of conformal symmetry in the IR. (paper)

  12. Numerical approach of multi-field two-phase flow models in the OVAP code

    International Nuclear Information System (INIS)

    Anela Kumbaro

    2005-01-01

    use full Eigen-structure information. Basic comparisons in terms of numerical results and physical modeling will be provided and interpreted. The intent is to provide guidelines for future development of such methods and models. References: [1] Lahey, R.T. Jr., Drew D.A. An Analysis of Two-Phase Flow and Heat Transfer using a Multidimensional, Multi-Field, Two-Fluid Computational Fluid Dynamics (CFD) Model, Japan/US Seminar on Two-Phase Flow Dynamics, California, June 5-8, 2000. [2] Lo S., Some recent developments and applications of CFD to multiphase flows in stirred reactors, AMIF-ESF Workshop, Computing two-phase flows, Aussois, 2000. [3] Roe P.L., Approximate Riemann solvers, parameter vectors, and difference schemes, J. Comp. Phys., 43(2), 1981. [4] Toumi and A. Kumbaro, An Approximate Linearized Riemann Solver for a Two-Fluid Model, J. Comput. Phys., 124, 286-300, 1996. [5] A. Kumbaro, I. Toumi and V. Seignole, Numerical Modeling of Two-Phase Flows Using Advanced Two Fluid Systems, Tenth International Conference on Nuclear Engineering, April 14-18 2002, Arlington, Virginia, USA. (author)

  13. Relative Contribution of the Hydrogen 2 s Two-Photon Decay and Lyman- α Escape Channels during the Epoch of Cosmological Recombination

    Science.gov (United States)

    Rubiño-Martin, J. A.; Sunyaev, R. A.

    2018-01-01

    We discuss the evolution of the ratio in number of recombinations due to 2 s two photon escape and due to the escape of Lyman- α photons from the resonance during the epoch of cosmological recombination, within the width of the last scattering surface and near its boundaries. We discuss how this ratio evolves in time, and how it defines the profile of the Lyman- α line in the spectrum of CMB. One of the key reasons for explaining its time dependence is the strong overpopulation of the 2 p level relative to the 2 s level at redshifts z ≲ 750.

  14. Gamma ray measurements in the reactions 23Na(p,γ)24Mg and 31P(p,γ)32S

    International Nuclear Information System (INIS)

    Boydell, S.G.

    1974-01-01

    Accurate branching ratio values for twenty-two resonances in the reaction 23 Na(p,γ) 24 Mg and twenty-five resonances in the reaction 31 P(p,γ) 32 S have been measured with Ge(Li) spectrometers. The values were necessary for the accurate analysis of work of astrophysical interest, and also used for the assignment of possible Jsupπ values to nuclear levels. The two spectrometers used were calibrated for relative peak efficiency independently of previous Ge(Li) work; the calibrations were accurate to 6% and 10%. Extensive calculations were made of the finite solid angle effects of the detector on anisotropic gamma rays; the calculations were valid for geometries where the source did not lie on the detector axis. Work was carried out at the Australian Atomic Energy Commission; this was made possible by the assistance of the Australian Institute of Nuclear Science and Engineering. (author)

  15. Measurement of transient two-phase flow velocity using statistical signal analysis of impedance probe signals

    International Nuclear Information System (INIS)

    Leavell, W.H.; Mullens, J.A.

    1981-01-01

    A computational algorithm has been developed to measure transient, phase-interface velocity in two-phase, steam-water systems. The algorithm will be used to measure the transient velocity of steam-water mixture during simulated PWR reflood experiments. By utilizing signals produced by two, spatially separated impedance probes immersed in a two-phase mixture, the algorithm computes the average transit time of mixture fluctuations moving between the two probes. This transit time is computed by first, measuring the phase shift between the two probe signals after transformation to the frequency domain and then computing the phase shift slope by a weighted least-squares fitting technique. Our algorithm, which has been tested with both simulated and real data, is able to accurately track velocity transients as fast as 4 m/s/s

  16. Condensation in a two-phase pool

    International Nuclear Information System (INIS)

    Duffey, R.B.; Hughes, E.D.

    1991-01-01

    We consider the case of vapor condensation in a liquid pool, when the heat transfer is controlled by heat losses through the walls. The analysis is based on drift flux theory for phase separation in the pool, and determines the two-phase mixture height for the pool. To our knowledge this is the first analytical treatment of this classic problem that gives an explicit result, previous work having established the result for the evaporative case. From conservation of mass and energy in a one-dimensional steady flow, together with a void relation between the liquid and vapor fluxes, we determine the increase in the mixture level from the base level of the pool. It can be seen that the thermal and hydrodynamic influences are separable. Thus, the thermal influence of the wall heat transfer appears through its effect on the condensing length L*, so that at high condensation rates the pool is all liquid, and at low rates overflows (the level swell or foaming effect). Similarly, the phase separation effect hydrodynamically determines the height via the relative velocity of the mixture to the entering flux. We examine some practical applications of this result to level swell in condensing flows, and also examine some limits in ideal cases

  17. Magnetism in the p-type Monolayer II-VI semiconductors SrS and SrSe

    Science.gov (United States)

    Lin, Heng-Fu; Lau, Woon-Ming; Zhao, Jijun

    2017-01-01

    Using density functional theory calculations, we study the electronic and magnetic properties of the p-type monolayer II-VI semiconductors SrX (X = S,Se). The pristine SrS and SrSe monolayers are large band gap semiconductor with a very flat band in the top valence band. Upon injecting hole uniformly, ferromagnetism emerges in those system in a large range of hole density. By varying hole density, the systems also show complicated phases transition among nonmagnetic semiconductor, half metal, magnetic semiconductor, and nonmagnetic metal. Furthermore, after introducing p-type dopants in SrS and SrSe via substitutionary inserting P (or As) dopants at the S (or Se) sites, local magnetic moments are formed around the substitutional sites. The local magnetic moments are stable with the ferromagnetic order with appreciable Curie temperature. The ferromagnetism originates from the instability of the electronic states in SrS and SrSe with the large density of states at the valence band edge, which demonstrates a useful strategy for realizing the ferromagnetism in the two dimensional semiconductors. PMID:28378761

  18. Phase equilibria in the Mo-Fe-P system at 800 °C and structure of ternary phosphide (Mo(1-x)Fe(x))3P (0.10 ≤ x ≤ 0.15).

    Science.gov (United States)

    Oliynyk, Anton O; Lomnytska, Yaroslava F; Dzevenko, Mariya V; Stoyko, Stanislav S; Mar, Arthur

    2013-01-18

    Construction of the isothermal section in the metal-rich portion (ternary phases: (Mo(1-x)Fe(x))(2)P (x = 0.30-0.82) and (Mo(1-x)Fe(x))(3)P (x = 0.10-0.15). The occurrence of a Co(2)Si-type ternary phase (Mo(1-x)Fe(x))(2)P, which straddles the equiatomic composition MoFeP, is common to other ternary transition-metal phosphide systems. However, the ternary phase (Mo(1-x)Fe(x))(3)P is unusual because it is distinct from the binary phase Mo(3)P, notwithstanding their similar compositions and structures. The relationship has been clarified through single-crystal X-ray diffraction studies on Mo(3)P (α-V(3)S-type, space group I42m, a = 9.7925(11) Å, c = 4.8246(6) Å) and (Mo(0.85)Fe(0.15))(3)P (Ni(3)P-type, space group I4, a = 9.6982(8) Å, c = 4.7590(4) Å) at -100 °C. Representation in terms of nets containing fused triangles provides a pathway to transform these closely related structures through twisting. Band structure calculations support the adoption of these structure types and the site preference of Fe atoms. Electrical resistivity measurements on (Mo(0.85)Fe(0.15))(3)P reveal metallic behavior but no superconducting transition.

  19. Statistics of light deflection in a random two-phase medium

    International Nuclear Information System (INIS)

    Sviridov, A P

    2007-01-01

    The statistics of the angles of light deflection during its propagation in a random two-phase medium with randomly oriented phase interfaces is considered within the framework of geometrical optics. The probabilities of finding a randomly walking photon in different phases of the inhomogeneous medium are calculated. Analytic expressions are obtained for the scattering phase function and the scattering phase matrix which relates the Stokes vector of the incident light beam with the Stokes vectors of deflected beams. (special issue devoted to multiple radiation scattering in random media)

  20. A simple image-reject mixer based on two parallel phase modulators

    Science.gov (United States)

    Hu, Dapeng; Zhao, Shanghong; Zhu, Zihang; Li, Xuan; Qu, Kun; Lin, Tao; Zhang, Kun

    2018-02-01

    A simple photonic microwave image-reject mixer (IRM) using two parallel phase modulators is proposed. First, a photonic microwave mixer with phase shift ability is achieved using two parallel phase modulators (PMs), an optical bandpass filter, three polarization controllers, three polarization beam splitters and two balanced photodetectors. At the output of the mixer, two frequency downconverted signals with tunable frequency difference can be obtained. By adjusting the phase difference as 90° and utilizing an electrical 90° hybrid, the useless components can be eliminated, and the image reject operation is realized. The key advantage of the proposed scheme is the usage of PM, which avoid the DC bias shifting problem and make the system simple and stable. A simulation is performed to verify the proposed scheme, a relative - 90° or 90° phase shift can be obtained between the two output ports of the photonic microwave mixer, at the output of the IRM, 60 dB image-reject ratio is obtained.

  1. Relation between the occurrence of Burnout and differential pressure fluctuation characteristics caused by the disturbance waves passing by a flow obstacle in a vertical boiling two-phase upward flow in a narrow annular channel

    Energy Technology Data Exchange (ETDEWEB)

    Mori, Shoji [Yokohama National University, Yokohama 240-8501 (Japan)]. E-mail: morisho@ynu.ac.jp; Fukano, Tohru [Kurume Institute of University, Fukuoka 830-0052 (Japan)]. E-mail: fukanot@cc.kurume-it.ac.jp

    2006-05-15

    If a flow obstacle such as a spacer is placed in a boiling two-phase flow within a channel, the temperature on the surface of the heating tube is severely affected by the existence of the spacer. Under certain conditions the spacer has a cooling effect, and under other conditions the spacer causes dryout of the cooling water film on the heating surface, resulting in burnout of the tube. The burnout mechanism near the spacer, however, remains unclear. In a previous paper (Fukano, T., Mori, S., Akamatsu, S., Baba, A., 2002. Relation between temperature fluctuation of a heating surface and generation of drypatch caused by a cylindrical spacer in a vertical boiling two-phase upward flow in a narrow annular channel. Nucl. Eng. Des. 217, 81-90), we reported that the disturbance wave has a significant effect on dryout occurrence. Therefore, in the present paper, the relation between dryout, burnout occurrence, and interval between two successive disturbance waves obtained from the differential pressure fluctuation caused by the disturbance waves passing by a spacer, is further discussed in detail.

  2. Relation between the occurrence of Burnout and differential pressure fluctuation characteristics caused by the disturbance waves passing by a flow obstacle in a vertical boiling two-phase upward flow in a narrow annular channel

    International Nuclear Information System (INIS)

    Mori, Shoji; Fukano, Tohru

    2006-01-01

    If a flow obstacle such as a spacer is placed in a boiling two-phase flow within a channel, the temperature on the surface of the heating tube is severely affected by the existence of the spacer. Under certain conditions the spacer has a cooling effect, and under other conditions the spacer causes dryout of the cooling water film on the heating surface, resulting in burnout of the tube. The burnout mechanism near the spacer, however, remains unclear. In a previous paper (Fukano, T., Mori, S., Akamatsu, S., Baba, A., 2002. Relation between temperature fluctuation of a heating surface and generation of drypatch caused by a cylindrical spacer in a vertical boiling two-phase upward flow in a narrow annular channel. Nucl. Eng. Des. 217, 81-90), we reported that the disturbance wave has a significant effect on dryout occurrence. Therefore, in the present paper, the relation between dryout, burnout occurrence, and interval between two successive disturbance waves obtained from the differential pressure fluctuation caused by the disturbance waves passing by a spacer, is further discussed in detail

  3. Two pedigrees of familial advanced sleep phase syndrome in Japan.

    Science.gov (United States)

    Satoh, Kohtoku; Mishima, Kazuo; Inoue, Yuichi; Ebisawa, Takashi; Shimizu, Tetsuo

    2003-06-15

    To determine whether a known missense mutation (bp2106 A/G) in hPer2 (a human homolog of the Drosophila period gene) for familial advanced sleep phase syndrome in a Caucasian family is involved in Japanese familial advanced sleep phase syndrome pedigrees. We identified 2 new Japanese families with advanced sleep phase syndrome, and a systematic survey was carried out in 28 relatives of theses 2 families. A total of 9 affected subjects were identified. The affected members showed significantly strong morningness tendencies compared with the unaffected members in various circadian parameters including the Horne-Ostberg Morningness-Eveningness Questionnaire score (77.3 +/- 4.8 vs 57.5 +/- 7.6, p sleep-onset time (20:45 +/- 75 min vs 23:16 +/- 64 min, p DNA samples were obtained from 7 affected and 7 unaffected subjects. None of the tested subjects possessed the missense mutation (bp2106 A/G) in hPer2. Furthermore, there is no significant linkage between affected subjects with hPer2 region by 2-point mapping and by direct sequencing of 23 exons of hPer2. These findings support the notion of genetic heterogeneity of familial advanced sleep phase syndrome cases in humans. The search for more familial advanced sleep phase syndrome cases and for loci other than hPer2 are necessary to further examine the roles of circadian-related genes in genetically determined human circadian rhythm disorders.

  4. Current-phase relation of a Bose-Einstein condensate flowing through a weak link

    International Nuclear Information System (INIS)

    Piazza, F.; Smerzi, A.; Collins, L. A.

    2010-01-01

    We study the current-phase relation of a Bose-Einstein condensate flowing through a repulsive square barrier by solving analytically the one-dimensional Gross-Pitaevskii equation. The barrier height and width fix the current-phase relation j(δφ), which tends to j∼cos(δφ/2) for weak barriers and to the Josephson sinusoidal relation j∼sin(δφ) for strong barriers. Between these two limits, the current-phase relation depends on the barrier width. In particular, for wide-enough barriers, we observe two families of multivalued current-phase relations. Diagrams belonging to the first family, already known in the literature, can have two different positive values of the current at the same phase difference. The second family, new to our knowledge, can instead allow for three different positive currents still corresponding to the same phase difference. Finally, we show that the multivalued behavior arises from the competition between hydrodynamic and nonlinear-dispersive components of the flow, the latter due to the presence of a soliton inside the barrier region.

  5. Phase diagram of Pr-P system

    International Nuclear Information System (INIS)

    Mironov, K.E.

    1981-01-01

    An area of the Pr-P system, adjoining to the Pr ordinate, is plotted up by the DTA method. Presence of P solid solution in Pr is established. Data on thermal stability of PrP, PrP 2 , PrP 5 and PrP 7 are generalized. The diagram of phase transformations in Pr-P system is plotted up proceeding from the whole complex of the data, presented. A supposition is made on a possible formation of solid solutions between the highest polyphosphide and phosphorus [ru

  6. THE FOSSIL RECORD OF TWO-PHASE GALAXY ASSEMBLY: KINEMATICS AND METALLICITIES IN THE NEAREST S0 GALAXY

    International Nuclear Information System (INIS)

    Arnold, Jacob A.; Romanowsky, Aaron J.; Brodie, Jean P.; Chomiuk, Laura; Strader, Jay; Spitler, Lee R.; Forbes, Duncan A.; Benson, Andrew J.

    2011-01-01

    We present a global analysis of kinematics and metallicity in the nearest S0 galaxy, NGC 3115, along with implications for its assembly history. The data include high-quality wide-field imaging from Suprime-Cam on the Subaru telescope, and multi-slit spectra of the field stars and globular clusters (GCs) obtained using Keck-DEIMOS/LRIS and Magellan-IMACS. Within two effective radii, the bulge (as traced by the stars and metal-rich GCs) is flattened and rotates rapidly (v/σ ∼> 1.5). At larger radii, the rotation declines dramatically to v/σ ∼ 0.7, but remains well aligned with the inner regions. The radial decrease in characteristic metallicity of both the metal-rich and metal-poor GC subpopulations produces strong gradients with power-law slopes of -0.17 ± 0.04 and -0.38 ± 0.06 dex dex -1 , respectively. We argue that this pattern is not naturally explained by a binary major merger, but instead by a two-phase assembly process where the inner regions have formed in an early violent, dissipative phase, followed by the protracted growth of the outer parts via minor mergers with typical mass ratios of ∼15-20:1.

  7. MODELLING THE INTERACTION IN GAME SPORTS - RELATIVE PHASE AND MOVING CORRELATIONS

    Directory of Open Access Journals (Sweden)

    Martin Lames

    2006-12-01

    Full Text Available Model building in game sports should maintain the constitutive feature of this group of sports, the dynamic interaction process between the two parties. For single net/wall games relative phase is suggested to describe the positional interaction between the two players. 30 baseline rallies in tennis were examined and relative phase was calculated by Hilbert transform from the two time-series of lateral displacement and trajectory in the court respectively. Results showed that relative phase indicates some aspects of the tactical interaction in tennis. At a more abstract level the interaction between two teams in handball was studied by examining the relationship of the two scoring processes. Each process can be conceived as a random walk. Moving averages of the scoring probabilities indicate something like a momentary strength. A moving correlation (length = 20 ball possessions describes the momentary relationship between the teams' strength. Evidence was found that this correlation is heavily time-dependent, in almost every single game among the 40 examined ones we found phases with a significant positive as well as significant negative relationship. This underlines the importance of a dynamic view on the interaction in these games.

  8. Enhanced mixing in two-phase Taylor-Couette flows

    International Nuclear Information System (INIS)

    Dherbecourt, Diane

    2015-01-01

    In the scope of the nuclear fuel reprocessing, Taylor-Couette flows between two concentric cylinders (the inner one in rotation and the outer one at rest) are used at laboratory scale to study the performances of new liquid/liquid extraction processes. Separation performances are strongly related to the mixing efficiency, the quantification of the latter is therefore of prime importance. A previous Ph.D. work has related the mixing properties to the hydrodynamics parameters in single-phase flow, using both experimental and numerical investigations. The Reynolds number, flow state and vortices height (axial wavelength) impacts were thus highlighted. This Ph.D. work extends the previous study to two-phase configurations. For experimental simplification, and to avoid droplets coalescence or breakage, spherical solid particles of PMMA from 800 μm to 1500 μm diameter are used to model rigid droplets. These beads are suspended in an aqueous solution of dimethyl sulfoxide (DMSO) and potassium Thiocyanate (KSCN). The experimental setup uses coupled Particle Image Velocimetry (PIV) and Planar Laser-Induced Fluorescence (PLIF) to access simultaneously the hydrodynamic and the mixing properties. Although the two phases are carefully chosen to match in density and refractive index, these precautions are not sufficient to ensure a good measurement quality, and a second PLIF channel is added to increase the precision of the mixing quantification. The classical PLIF channel monitors the evolution of Rhodamine WT concentration, while the additional PLIF channel is used to map a Fluorescein dye, which is homogeneously concentrated inside the gap. This way, a dynamic mask of the bead positions can be created and used to correct the Rhodamine WT raw images. Thanks to this experimental setup, a parametric study of the particles size and concentration is achieved. A double effect of the dispersed phase is evidenced. On one hand, the particles affect the flow hydrodynamic properties

  9. Observation of $\\eta_{c}(2S) \\to p \\bar p$ and search for $X(3872) \\to p \\bar p$ decays

    CERN Document Server

    Aaij, Roel

    2017-06-10

    The first observation of the decay $\\eta_{c}(2S) \\to p \\bar p$ is reported using proton-proton collision data corresponding to an integrated luminosity of $3.0\\rm \\, fb^{-1}$ recorded by the LHCb experiment at centre-of-mass energies of 7 and 8 TeV. The $\\eta_{c}(2S)$ resonance is produced in the decay $B^{+} \\to [c\\bar c] K^{+}$. The product of branching fractions normalised to that for the $J/\\psi$ intermediate state, ${\\cal R}_{\\eta_{c}(2S)}$, is measured to be \\begin{align*} {\\cal R}_{\\eta_{c}(2S)}\\equiv\\frac{{\\mathcal B}(B^{+} \\to \\eta_{c}(2S) K^{+}) \\times {\\mathcal B}(\\eta_{c}(2S) \\to p \\bar p)}{{\\mathcal B}(B^{+} \\to J/\\psi K^{+}) \\times {\\mathcal B}(J/\\psi\\to p \\bar p)} =~& (1.58 \\pm 0.33 \\pm 0.09)\\times 10^{-2}, \\end{align*} where the first uncertainty is statistical and the second systematic. No signals for the decays $B^{+} \\to X(3872) (\\to p \\bar p) K^{+}$ and $B^{+} \\to \\psi(3770) (\\to p \\bar p) K^{+}$ are seen, and the 95\\% confidence level upper limits on their relative branching ratios ar...

  10. Cold water injection into two-phase mixtures

    International Nuclear Information System (INIS)

    1989-07-01

    This report presents the results of a review of the international literature regarding the dynamic loadings associated with the injection of cold water into two-phase mixtures. The review placed emphasis on waterhammer in nuclear power plants. Waterhammmer incidence data were reviewed for information related to thermalhydraulic conditions, underlying causes and consequential damage. Condensation induced waterhammer was found to be the most significant consequence of injecting cold water into a two-phase system. Several severe waterhammer incidents have been attributed to slug formation and steam bubble collapse under conditions of stratified steam and cold water flows. These phenomena are complex and not well understood. The current body of experimental and analytical knowledge is not large enough to establish maps of expected regimes of condensation induced waterhammer. The Electric Power Research Institute, in the United States, has undertaken a major research and development programme to develop the knowledge base for this area. The limited models and data currently available show that mechanical parameters are as important as thermodynamic conditions for the initiation of condensation induced waterhammer. Examples of bounds for avoiding two-phase waterhammer are given. These bounds are system specific and depend upon parameters such as pump capacity, pipe length and pipe orientation

  11. Soccer-related performance in eumenorrheic Tunisian high-level soccer players: effects of menstrual cycle phase and moment of day.

    Science.gov (United States)

    Tounsi, Mohamed; Jaafar, Hamdi; Aloui, Asma; Souissi, Nizar

    2018-04-01

    This study aimed to examine the combined effects of menstrual cycle phase and moment of day on female soccer players' performances in the five-jump test (5JT), the repeated shuttle-sprint ability test (RSSA), and the Yo-Yo intermittent recovery test level 1 (YYIRT1). Eleven eumenorrheic Tunisian high-level soccer players volunteered to participate. Each subject individually participated in three testing periods: one in the early follicular phase (menses), one in the late follicular phase, and another in the luteal phase. In each period, two test sessions were conducted: one at 07:30 and another at 17:30. The testing routines included the 5JT, the RSSA, and the YYIRT1. None of the measured variables were altered due to menstrual cycle phase (all P>0.05). Mean time during RSSA was significantly lower in the afternoon session compared to the morning session (8.48±0.27 s and 8.77±0.34 s, respectively, P<0.001), while 5JT performance was significantly higher in the afternoon compared to the morning (9.08±0.58 m and 8.60±0.56 m, respectively, P<0.001). Soccer-specific endurance as well as jumping and repeated sprinting ability of Tunisian female high-level soccer players are not affected due to menstrual cycle phase neither in the morning nor in the afternoon.

  12. Analytical solution of laminar-laminar stratified two-phase flows with curved interfaces

    International Nuclear Information System (INIS)

    Brauner, N.; Rovinsky, J.; Maron, D.M.

    1995-01-01

    The present study represents a complete analytical solution for laminar two-phase flows with curved interfaces. The solution of the Navier-Stokes equations for the two-phases in bipolar coordinates provides the 'flow monograms' describe the relation between the interface curvature and the insitu flow geometry when given the phases flow rates and viscosity ratios. Energy considerations are employed to construct the 'interface monograms', whereby the characteristic interfacial curvature is determined in terms of the phases insitu holdup, pipe diameter, surface tension, fluids/wall adhesion and gravitation. The two monograms are then combined to construct the system 'operational monogram'. The 'operational monogram' enables the determination of the interface configuration, the local flow characteristics, such as velocity profiles, wall and interfacial shear stresses distribution as well as the integral characteristics of the two-phase flow: phases insitu holdup and pressure drop

  13. Analytical solution of laminar-laminar stratified two-phase flows with curved interfaces

    Energy Technology Data Exchange (ETDEWEB)

    Brauner, N.; Rovinsky, J.; Maron, D.M. [Tel-Aviv Univ. (Israel)

    1995-09-01

    The present study represents a complete analytical solution for laminar two-phase flows with curved interfaces. The solution of the Navier-Stokes equations for the two-phases in bipolar coordinates provides the `flow monograms` describe the relation between the interface curvature and the insitu flow geometry when given the phases flow rates and viscosity ratios. Energy considerations are employed to construct the `interface monograms`, whereby the characteristic interfacial curvature is determined in terms of the phases insitu holdup, pipe diameter, surface tension, fluids/wall adhesion and gravitation. The two monograms are then combined to construct the system `operational monogram`. The `operational monogram` enables the determination of the interface configuration, the local flow characteristics, such as velocity profiles, wall and interfacial shear stresses distribution as well as the integral characteristics of the two-phase flow: phases insitu holdup and pressure drop.

  14. An ATM-independent S-phase checkpoint response involves CHK1 pathway

    Science.gov (United States)

    Zhou, Xiang-Yang; Wang, Xiang; Hu, Baocheng; Guan, Jun; Iliakis, George; Wang, Ya

    2002-01-01

    After exposure to genotoxic stress, proliferating cells actively slow down the DNA replication through a S-phase checkpoint to provide time for repair. We report that in addition to the ataxia-telangiectasia mutated (ATM)-dependent pathway that controls the fast response, there is an ATM-independent pathway that controls the slow response to regulate the S-phase checkpoint after ionizing radiation in mammalian cells. The slow response of S-phase checkpoint, which is resistant to wortmannin, sensitive to caffeine and UCN-01, and related to cyclin-dependent kinase phosphorylation, is much stronger in CHK1 overexpressed cells, and it could be abolished by Chk1 antisense oligonucleotides. These results provide evidence that the ATM-independent slow response of S-phase checkpoint involves CHK1 pathway.

  15. S-phase checkpoint elements of the E2F-1 family increase radiosensitivity in fibrosarcoma cells lacking p53

    International Nuclear Information System (INIS)

    Bodis, Stephan; Pruschy, Martin; Wirbelauer, Christiane; Glanzmann, Christoph; Krek, Wilhelm

    1997-01-01

    Purpose: Correct advance of cells through the S-phase of the mammalian cell cycle depends on the timely controlled activity of the E2F-1 transcription factor by cyclin A-cdk2. We are studying the reproductive integrity and radiosensitation of isogenic mouse fibrosarcoma cells, differing only in their p53 status, after expression of E2F-1 wildtype (wt) and specific E2F-1 mutants (mt) lacking the cyclin-A-binding domain. In this tumor model system only p53 wild-type expressing tumor cells are sensitive to ionizing radiation in vitro and in vivo. Material and Methods: Either wild-type p53 or genetically engineered p53 'null' mouse embryo fibroblasts were transfected with the oncogenes E1A and ras. These otherwise isogenic fibrosarcoma cells, with a malignant phenotype and tumorigenic in nude mice, were transfected with retroviruses containing either E2F-1 wild-type or specific E2F-1 mutants lacking the cyclin-A binding domain. Reproductive integrity after E2F-1 transfection with or without ionizing radiation (RT) was tested using the clonogenic assay. Tumor cell morphology of treated cells is analyzed for cell death mechanism. Results: E2F-1 wild-type expression in fibrosarcoma cells induced a clear p53 dependent cell death. While clonogenic survival of p53 'null' tumor cells was only slightly reduced with the expression of E2F-1 wild type (survival fraction of 0.5), the clonogenic survival of p53 wild-type fibrosarcoma tumor cells was reduced by at least one logarithm (survival fraction of 0.05). However, expression of the specific E2F-1 mutant lacking the cyclin-A binding domain reduced clonogenic survival in both the p53 'null' and the p53 wild-type fibrosarcoma cells by at least 2 logarithms (survival fraction 0.01 for p53 'null' and 0.002 for p53 wild-type). The mean values of the survival fractions after 2 and 5 Gy radiation alone in p53 'null' fibrosarcoma cells (SF 2 and SF 5) were SF 2 0.7, SF 5 = 0.15, respectively. The combination of ionizing RT in the p53

  16. Critical review of conservation equations for two-phase flow in the U.S. NRC TRACE code

    International Nuclear Information System (INIS)

    Wulff, Wolfgang

    2011-01-01

    Research highlights: → Field equations as implemented in TRACE are incorrect. → Boundary conditions needed for cooling of nuclear fuel elements are wrong. → The two-fluid model in TRACE is not closed. → Three-dimensional flow modeling in TRACE has no basis. - Abstract: The field equations for two-phase flow in the computer code TRAC/RELAP Advanced Computational Engine or TRACE are examined to determine their validity, their capabilities and limitations in resolving nuclear reactor safety issues. TRACE was developed for the NRC to predict thermohydraulic phenomena in nuclear power plants during operational transients and postulated accidents. TRACE is based on the rigorously derived and well-established two-fluid field equations for 1-D and 3-D two-phase flow. It is shown that: (1)The two-fluid field equations for mass conservation as implemented in TRACE are wrong because local mass balances in TRACE are in conflict with mass conservation for the whole reactor system, as shown in Section . (2)Wrong equations of motion are used in TRACE in place of momentum balances, compromising at branch points the prediction of momentum transfer between, and the coupling of, loops in hydraulic networks by impedance (form loss and wall shear) and by inertia and thereby the simulation of reactor component interactions. (3)Most seriously, TRACE calculation of heat transfer from fuel elements is incorrect for single and two-phase flows, because Eq. of the TRACE Manual is wrong (see Section ). (4)Boundary conditions for momentum and energy balances in TRACE are restricted to flow regimes with single-phase wall contact because TRACE lacks constitutive relations for solid-fluid exchange of momentum and heat in prevailing flow regimes. Without a quantified assessment of consequences from (3) to (4), predictions of phasic fluid velocities, fuel temperatures and important safety parameters, e.g., peak clad temperature, are questionable. Moreover, TRACE cannot predict 3-D single- or

  17. Extension of CFD Codes Application to Two-Phase Flow Safety Problems - Phase 3

    International Nuclear Information System (INIS)

    Bestion, D.; Anglart, H.; Mahaffy, J.; Lucas, D.; Song, C.H.; Scheuerer, M.; Zigh, G.; Andreani, M.; Kasahara, F.; Heitsch, M.; Komen, E.; Moretti, F.; Morii, T.; Muehlbauer, P.; Smith, B.L.; Watanabe, T.

    2014-11-01

    . Identification of needs for additional experimental validation; - identification of a matrix of numerical benchmarks of special interest for the selected NRS problems; - establish the foundation of Best Practice Guidelines for two-phase CFD application to the selected NRS problems. This document is an extension of the first report produced by the Writing Group 3. A few NRS problems where two-phase CFD may bring real benefit are first selected to be further analysed in more detail according to some criteria. They must be high priority issues from the point of view of nuclear safety with some investigations going on and CFD investigations must have a reasonable chance to be successful in a reasonable period of time. They must address both the present generation of PWR and BWR and the Generation 3 water reactors and should possibly address all flow regimes so that they may, to some extent, envelop many other issues. A general multi-step methodology for application of two-phase CFD to nuclear safety issues is proposed. Many options are possible when using two phase CFD, for the basic model (one-fluid, two-fluid, multi-field,...), for the averaging or filtering of turbulent and two-phase scales (using RANS, LES,...), for the treatment of the interface either by an Interface Tracking Method or statistically by a volume fraction, an interfacial area equation,... The choices have to be justified after an in-depth analysis of the issue and an identification of all basic flow processes. Then closure relations have to be selected or developed for interfacial transfers, turbulent transfers and wall transfers, and a test matrix has to be established to validate all the models in a separate effect way. The method has been applied to the selected issues resulting in an updated state of the art and gaps were identified in the modelling. Available data for validation were reviewed and needs of additional data were identified. Verification tests were also identified. A few benchmarks are proposed

  18. Seismoelectric couplings in a poroelastic material containing two immiscible fluid phases

    Science.gov (United States)

    Jardani, A.; Revil, A.

    2015-08-01

    A new approach of seismoelectric imaging has been recently proposed to detect saturation fronts in which seismic waves are focused in the subsurface to scan its heterogeneous nature and determine saturation fronts. Such type of imaging requires however a complete modelling of the seismoelectric properties of porous media saturated by two immiscible fluid phases, one being usually electrically insulating (for instance water and oil). We combine an extension of Biot dynamic theory, valid for porous media containing two immiscible Newtonian fluids, with an extension of the electrokinetic theory based on the notion of effective volumetric charge densities dragged by the flow of each fluid phase. These effective charge densities can be related directly to the permeability and saturation of each fluid phase. The coupled partial differential equations are solved with the finite element method. We also derive analytically the transfer function connecting the macroscopic electrical field to the acceleration of the fast P wave (coseismic electrical field) and we study the influence of the water content on this coupling. We observe that the amplitude of the co-seismic electrical disturbance is very sensitive to the water content with an increase in amplitude with water saturation. We also investigate the seismoelectric conversions (interface effect) occurring at the water table. We show that the conversion response at the water table can be identifiable only when the saturation contrasts between the vadose and saturated zones are sharp enough. A relatively dry vadose zone represents the best condition to identify the water table through seismoelectric measurements. Indeed, in this case, the coseismic electrical disturbances are vanishingly small compared to the seismoelectric interface response.

  19. Reduced order modeling of flashing two-phase jets

    Energy Technology Data Exchange (ETDEWEB)

    Gurecky, William, E-mail: william.gurecky@utexas.edu; Schneider, Erich, E-mail: eschneider@mail.utexas.edu; Ballew, Davis, E-mail: davisballew@utexas.edu

    2015-12-01

    Highlights: • Accident simulation requires ability to quickly predict two-phase flashing jet's damage potential. • A reduced order modeling methodology informed by experimental or computational data is described. • Zone of influence volumes are calculated for jets of various upstream thermodynamic conditions. - Abstract: In the event of a Loss of Coolant Accident (LOCA) in a pressurized water reactor, the escaping coolant produces a highly energetic flashing jet with the potential to damage surrounding structures. In LOCA analysis, the goal is often to evaluate many break scenarios in a Monte Carlo style simulation to evaluate the resilience of a reactor design. Therefore, in order to quickly predict the damage potential of flashing jets, it is of interest to develop a reduced order model that relates the damage potential of a jet to the pressure and temperature upstream of the break and the distance from the break to a given object upon which the jet is impinging. This work presents framework for producing a Reduced Order Model (ROM) that may be informed by measured data, Computational Fluid Dynamics (CFD) simulations, or a combination of both. The model is constructed by performing regression analysis on the pressure field data, allowing the impingement pressure to be quickly reconstructed for any given upstream thermodynamic condition within the range of input data. The model is applicable to both free and fully impinging two-phase flashing jets.

  20. Extraction of Oxytetracycline Hydrochloride in Aqueous Two-phase System of Acetone and Ammonium Sulfate

    International Nuclear Information System (INIS)

    Han, J.

    2013-01-01

    Summary: Aqueous two-phase system (ATPS) is an efficient implement for separation of various substrates, and extracted by an aqueous two-phase system has been successful ly applied in the downstream processing of various biological compounds. In this research, the extraction of oxytetracycline hydrochloride (OTC-HCl) was carried out in an aqueous two-phase system containing acetone and ammonium sulfate solution, which partitioned the antibiotic to the upper phase. The effects of some parameters on the extraction efficiency of OTC-HCl were studied in detail, including temperature, the volume of acetone, the pH value of ammonium sulfate solution, the concentrations of (NH/sub 4/)/sub 2/ SO/sub 4/ and OTC-HCl. The results showed that the volume of acetone, the pH value of ammonium sulfate solution and the concentration of OTC-HCl in feed had significant effects on the extraction efficiency of OTC-HCl, but the effects of temperature on the extraction of OTC-HCl was not obvious. (author)

  1. Extraction of Oxytetracycline Hydrochloride in Aqueous Two-phase System of Acetone and Ammonium Sulfate

    Energy Technology Data Exchange (ETDEWEB)

    Han, J. [Jiangsu Univ., Zhenjiang (China). Dept. of Food and Biological Engineering

    2013-02-15

    Summary: Aqueous two-phase system (ATPS) is an efficient implement for separation of various substrates, and extracted by an aqueous two-phase system has been successful ly applied in the downstream processing of various biological compounds. In this research, the extraction of oxytetracycline hydrochloride (OTC-HCl) was carried out in an aqueous two-phase system containing acetone and ammonium sulfate solution, which partitioned the antibiotic to the upper phase. The effects of some parameters on the extraction efficiency of OTC-HCl were studied in detail, including temperature, the volume of acetone, the pH value of ammonium sulfate solution, the concentrations of (NH/sub 4/)/sub 2/ SO/sub 4/ and OTC-HCl. The results showed that the volume of acetone, the pH value of ammonium sulfate solution and the concentration of OTC-HCl in feed had significant effects on the extraction efficiency of OTC-HCl, but the effects of temperature on the extraction of OTC-HCl was not obvious. (author)

  2. Single-phase and two-phase anaerobic digestion of fruit and vegetable waste: Comparison of start-up, reactor stability and process performance

    Energy Technology Data Exchange (ETDEWEB)

    Ganesh, Rangaraj [INRA, UR50, Laboratoire de Biotechnologie de l’Environnement, Avenue des Etangs, Narbonne F-11100 (France); Torrijos, Michel, E-mail: michel.torrijos@supagro.inra.fr [INRA, UR50, Laboratoire de Biotechnologie de l’Environnement, Avenue des Etangs, Narbonne F-11100 (France); Sousbie, Philippe [INRA, UR50, Laboratoire de Biotechnologie de l’Environnement, Avenue des Etangs, Narbonne F-11100 (France); Lugardon, Aurelien [Naskeo Environnment, 52 rue Paul Vaillant Couturier, F-92240 Malakoff (France); Steyer, Jean Philippe; Delgenes, Jean Philippe [INRA, UR50, Laboratoire de Biotechnologie de l’Environnement, Avenue des Etangs, Narbonne F-11100 (France)

    2014-05-01

    Highlights: • Single-phase and two-phase systems were compared for fruit and vegetable waste digestion. • Single-phase digestion produced a methane yield of 0.45 m{sup 3} CH{sub 4}/kg VS and 83% VS removal. • Substrate solubilization was high in acidification conditions at 7.0 kg VS/m{sup 3} d and pH 5.5–6.2. • Energy yield was lower by 33% for two-phase system compared to the single-phase system. • Simple and straight-forward operation favored single phase process over two-phase process. - Abstract: Single-phase and two-phase digestion of fruit and vegetable waste were studied to compare reactor start-up, reactor stability and performance (methane yield, volatile solids reduction and energy yield). The single-phase reactor (SPR) was a conventional reactor operated at a low loading rate (maximum of 3.5 kg VS/m{sup 3} d), while the two-phase system consisted of an acidification reactor (TPAR) and a methanogenic reactor (TPMR). The TPAR was inoculated with methanogenic sludge similar to the SPR, but was operated with step-wise increase in the loading rate and with total recirculation of reactor solids to convert it into acidification sludge. Before each feeding, part of the sludge from TPAR was centrifuged, the centrifuge liquid (solubilized products) was fed to the TPMR and centrifuged solids were recycled back to the reactor. Single-phase digestion produced a methane yield of 0.45 m{sup 3} CH{sub 4}/kg VS fed and VS removal of 83%. The TPAR shifted to acidification mode at an OLR of 10.0 kg VS/m{sup 3} d and then achieved stable performance at 7.0 kg VS/m{sup 3} d and pH 5.5–6.2, with very high substrate solubilization rate and a methane yield of 0.30 m{sup 3} CH{sub 4}/kg COD fed. The two-phase process was capable of high VS reduction, but material and energy balance showed that the single-phase process was superior in terms of volumetric methane production and energy yield by 33%. The lower energy yield of the two-phase system was due to the loss of

  3. Single-phase and two-phase anaerobic digestion of fruit and vegetable waste: Comparison of start-up, reactor stability and process performance

    International Nuclear Information System (INIS)

    Ganesh, Rangaraj; Torrijos, Michel; Sousbie, Philippe; Lugardon, Aurelien; Steyer, Jean Philippe; Delgenes, Jean Philippe

    2014-01-01

    Highlights: • Single-phase and two-phase systems were compared for fruit and vegetable waste digestion. • Single-phase digestion produced a methane yield of 0.45 m 3 CH 4 /kg VS and 83% VS removal. • Substrate solubilization was high in acidification conditions at 7.0 kg VS/m 3 d and pH 5.5–6.2. • Energy yield was lower by 33% for two-phase system compared to the single-phase system. • Simple and straight-forward operation favored single phase process over two-phase process. - Abstract: Single-phase and two-phase digestion of fruit and vegetable waste were studied to compare reactor start-up, reactor stability and performance (methane yield, volatile solids reduction and energy yield). The single-phase reactor (SPR) was a conventional reactor operated at a low loading rate (maximum of 3.5 kg VS/m 3 d), while the two-phase system consisted of an acidification reactor (TPAR) and a methanogenic reactor (TPMR). The TPAR was inoculated with methanogenic sludge similar to the SPR, but was operated with step-wise increase in the loading rate and with total recirculation of reactor solids to convert it into acidification sludge. Before each feeding, part of the sludge from TPAR was centrifuged, the centrifuge liquid (solubilized products) was fed to the TPMR and centrifuged solids were recycled back to the reactor. Single-phase digestion produced a methane yield of 0.45 m 3 CH 4 /kg VS fed and VS removal of 83%. The TPAR shifted to acidification mode at an OLR of 10.0 kg VS/m 3 d and then achieved stable performance at 7.0 kg VS/m 3 d and pH 5.5–6.2, with very high substrate solubilization rate and a methane yield of 0.30 m 3 CH 4 /kg COD fed. The two-phase process was capable of high VS reduction, but material and energy balance showed that the single-phase process was superior in terms of volumetric methane production and energy yield by 33%. The lower energy yield of the two-phase system was due to the loss of energy during hydrolysis in the TPAR and the

  4. Two-phase flow in refrigeration systems

    CERN Document Server

    Gu, Junjie; Gan, Zhongxue

    2013-01-01

    Two-Phase Flow in Refrigeration Systems presents recent developments from the authors' extensive research programs on two-phase flow in refrigeration systems. This book covers advanced mass and heat transfer and vapor compression refrigeration systems and shows how the performance of an automotive air-conditioning system is affected through results obtained experimentally and theoretically, specifically with consideration of two-phase flow and oil concentration. The book is ideal for university postgraduate students as a textbook, researchers and professors as an academic reference book, and b

  5. Research on boiling and two-phase flow

    International Nuclear Information System (INIS)

    Marinsek, Z.; Gaspersic, B.; Pavselj, D.; Tomsic, M.

    1977-01-01

    Report consists of three contributions. Experimental apparatus with pressure chamber (up to 25 bar and 250 deg C) was constructed including optical bubble detection device, and test measurements of mutual influence of boiling bubbles from two adjacent nucleation sites were performed; for analyses, a computer programme package for coincidence analyses of events was made, including data acquisition hardware. Two-phase pressure drop in subcooled Vertical annular water flow was measured, for pressures up to 10 bar, mass velocity 500 to 760 kg/m 2 s and vapour quality 0 to .01. Results agree fairly well with Martinelli-Nelson model

  6. Generalized network modeling of capillary-dominated two-phase flow.

    Science.gov (United States)

    Raeini, Ali Q; Bijeljic, Branko; Blunt, Martin J

    2018-02-01

    We present a generalized network model for simulating capillary-dominated two-phase flow through porous media at the pore scale. Three-dimensional images of the pore space are discretized using a generalized network-described in a companion paper [A. Q. Raeini, B. Bijeljic, and M. J. Blunt, Phys. Rev. E 96, 013312 (2017)2470-004510.1103/PhysRevE.96.013312]-which comprises pores that are divided into smaller elements called half-throats and subsequently into corners. Half-throats define the connectivity of the network at the coarsest level, connecting each pore to half-throats of its neighboring pores from their narrower ends, while corners define the connectivity of pore crevices. The corners are discretized at different levels for accurate calculation of entry pressures, fluid volumes, and flow conductivities that are obtained using direct simulation of flow on the underlying image. This paper discusses the two-phase flow model that is used to compute the averaged flow properties of the generalized network, including relative permeability and capillary pressure. We validate the model using direct finite-volume two-phase flow simulations on synthetic geometries, and then present a comparison of the model predictions with a conventional pore-network model and experimental measurements of relative permeability in the literature.

  7. Generalized network modeling of capillary-dominated two-phase flow

    Science.gov (United States)

    Raeini, Ali Q.; Bijeljic, Branko; Blunt, Martin J.

    2018-02-01

    We present a generalized network model for simulating capillary-dominated two-phase flow through porous media at the pore scale. Three-dimensional images of the pore space are discretized using a generalized network—described in a companion paper [A. Q. Raeini, B. Bijeljic, and M. J. Blunt, Phys. Rev. E 96, 013312 (2017), 10.1103/PhysRevE.96.013312]—which comprises pores that are divided into smaller elements called half-throats and subsequently into corners. Half-throats define the connectivity of the network at the coarsest level, connecting each pore to half-throats of its neighboring pores from their narrower ends, while corners define the connectivity of pore crevices. The corners are discretized at different levels for accurate calculation of entry pressures, fluid volumes, and flow conductivities that are obtained using direct simulation of flow on the underlying image. This paper discusses the two-phase flow model that is used to compute the averaged flow properties of the generalized network, including relative permeability and capillary pressure. We validate the model using direct finite-volume two-phase flow simulations on synthetic geometries, and then present a comparison of the model predictions with a conventional pore-network model and experimental measurements of relative permeability in the literature.

  8. Development of backward equations T(p,h), T(p,s) and p(h,s) for heavy water liquid and vapor

    International Nuclear Information System (INIS)

    Nick P Petropoulos; Simos E Simopoulos

    2005-01-01

    Full text of publication follows: Backward equations for heavy water (a) temperature as a function of pressure and enthalpy T(p,h), (b) temperature as a function of pressure and entropy T(p,s) and (c) pressure as a function of enthalpy and entropy p(h,s) presented in this work, are based on the 'IAPS Formulation 1984 for the Thermodynamic Properties of Heavy Water Substance' [1], and also on the respective equations for the ordinary water substance as presented in 'The IAPWS Industrial Formulation 1997 for the Thermodynamic Properties of Water and Steam' [2]. Heavy water and steam thermodynamic properties can be calculated using the basic equations and saturation equations that are included in [1]. However, [1] does not contain any backward functions T(p,h), T(p,s) and p(h,s), which are needed for heavy water thermodynamic process modeling. The development of the two temperature backward functions efficiently increases computational speed for temperature calculations more than three times as pointed out in the similar case problem for ordinary water, addressed successfully in [2]. Without these temperature backward functions calculations may be performed only iteratively using the heavy water state equations at a much greater computing cost. Moreover, the development of the pressure backward function saves even more computing time in modeling problems since two-dimensional iterations from the h(p,T) and s(p,T) heavy water functions may by effectively avoided. In addition, given the pressure function p(h,s), the heavy water temperature T(h,s) can be calculated by the temperature function T(p,h). The numerical consistencies of calculated T and p to the state equations included in [1] are sufficient for most applications in the heavy water nuclear reactors heat cycles. For applications, where the demands on numerical consistency and accuracy are rather high, iterations with the approved state equations may be necessary. In these cases both temperature and pressure

  9. Photostability enhancement of InP/ZnS quantum dots enabled by In{sub 2}O{sub 3} overcoating

    Energy Technology Data Exchange (ETDEWEB)

    Jo, Jung-Ho; Kim, Jong-Hoon; Lee, Sun-Hyoung [Department of Materials Science and Engineering, Hongik University, Seoul 121-791 (Korea, Republic of); Jang, Ho Seong [Center for Materials Architecturing, Korea Institute of Science and Technology, Seoul 136-791 (Korea, Republic of); Jang, Dong Seon; Lee, Ju Chul; Park, Ko Un; Choi, Yoonyoung [Advanced Materials Team, Materials & Devices Advanced Research Institute, LG Electronics, Seoul 137-724 (Korea, Republic of); Ha, Chunghun, E-mail: chunghun.ha@hongik.ac.kr [School of Information & Computer Engineering, Hongik University, Seoul 121-791 (Korea, Republic of); Yang, Heesun, E-mail: hyang@hongik.ac.kr [Department of Materials Science and Engineering, Hongik University, Seoul 121-791 (Korea, Republic of)

    2015-10-25

    Although the present-level quantum dots (QDs) exhibit excellent photoluminescent performance, their photostability under a prolonged photoexcitation stays doubtful and still unsatisfactory from an industrial perspective, since it determines the reliability of QD-incorporated devices such as QD-light-emitting diodes (QD-LEDs). In the present work, the overcoating of red-emitting InP/ZnS QDs with the oxide phase of In{sub 2}O{sub 3} is attempted to suppress the QD photooxidation, thus rendering them highly photostable. The efficacy of the oxide overlayer in substantially alleviating the QD photodegradation is verified through a comparative photostability test, where two colloidal solutions of bare versus In{sub 2}O{sub 3}-overcoated InP/ZnS (InP/ZnS@In{sub 2}O{sub 3}) QDs are identically subjected to a continuous UV irradiation for an extended period of time. Furthermore, both InP/ZnS and InP/ZnS@In{sub 2}O{sub 3} QDs are packaged as color-converters with a blue LED chip, and the operational stability of the fabricated QD-LEDs is examined at a forward bias of 60 mA. Consistent with the results of UV irradiation experiment, InP/ZnS@In{sub 2}O{sub 3} QD-LED exhibits a superior device stability against a continual operation as compared with InP/ZnS one. - Graphical abstract: In{sub 2}O{sub 3}-overcoated InP/ZnS QD exhibited the superior photostability under continuous UV irradiation and LED operation for extended period of times compared to bare InP/ZnS one. - Highlights: • Red-emitting InP/ZnS QD is overcoated with the oxide phase of In{sub 2}O{sub 3}. • The efficacy of the oxide overlayer in substantially alleviating the QD photodegradation is demonstrated. • Compared to bare InP/ZnS QD In{sub 2}O{sub 3}-overcoated one exhibits the superior photostability against continuous photoexcitation.

  10. Optimization of the thermodynamic properties and phase diagrams of P2O5-containing systems

    Science.gov (United States)

    Hudon, Pierre; Jung, In-Ho

    2014-05-01

    P2O5 is an important oxide component in the late stage products of numerous igneous rocks such as granites and pegmatites. Typically, P2O5 combines with CaO and crystallizes in the form of apatite, while in volatile-free conditions, Ca-whitlockite is formed. In spite of their interest, the thermodynamic properties and phase diagrams of P2O5-containg systems are not well known yet. In the case of the pure P2O5 for example, no experimental thermodynamic data are available for the liquid and the O and O' solid phases. As a result, we re-evaluated all the thermodynamic and phase diagram data of the P2O5 unary system [1]. Optimization of the thermodynamic properties and phase diagrams of the binary P2O5 systems was then performed including the Li2O-, Na2O-, MgO-, CaO-, BaO-, MnO-, FeO-, Fe2O3-, ZnO-, Al2O3-, and SiO2-P2O5 [2] systems. All available thermodynamic and phase equilibrium data were simultaneously reproduced in order to obtain a set of model equations for the Gibbs energies of all phases as functions of temperature and composition. In particular, the Gibbs energy of the liquid solution was described using the Modified Quasichemical Model [3-5] implemented in the FactSage software [6]. Thermodynamic modeling of the Li2O-Na2O-K2O-MgO-CaO-FeO-Fe2O3-Al2O3-SiO2 system, which include many granite-forming minerals such as nepheline, leucite, pyroxene, melilite, feldspar and spinel is currently in progress. [1] Jung, I.-H., Hudon, P. (2012) Thermodynamic assessment of P2O5. J. Am. Ceram. Soc., 95 (11), 3665-3672. [2] Rahman, M., Hudon, P. and Jung, I.-H. (2013) A coupled experimental study and thermodynamic modeling of the SiO2-P2O5 system. Metall. Mater. Trans. B, 44 (4), 837-852. [3] Pelton, A.D. and Blander, M. (1984) Computer-assisted analysis of the thermodynamic properties and phase diagrams of slags. Proc. AIME Symp. Metall. Slags Fluxes, TMS-AIME, 281-294. [4] Pelton, A.D. and Blander, M. (1986) Thermodynamic analysis of ordered liquid solutions by a modified

  11. Topological Phase Diagrams of Bulk and Monolayer TiS2−xTex

    KAUST Repository

    Zhu, Zhiyong

    2013-02-12

    With the use of ab initio calculations, the topological phase diagrams of bulk and monolayer TiS2−xTex are established. Whereas bulk TiS2−xTex shows two strong topological phases [1;(000)] and [1;(001)] for 0.44S2−xTex is a unique system for studying topological phases in three and two dimensions simultaneously.

  12. Topological Phase Diagrams of Bulk and Monolayer TiS2−xTex

    KAUST Repository

    Zhu, Zhiyong; Cheng, Yingchun; Schwingenschlö gl, Udo

    2013-01-01

    With the use of ab initio calculations, the topological phase diagrams of bulk and monolayer TiS2−xTex are established. Whereas bulk TiS2−xTex shows two strong topological phases [1;(000)] and [1;(001)] for 0.44S2−xTex is a unique system for studying topological phases in three and two dimensions simultaneously.

  13. A Complex Solar Coronal Jet with Two Phases

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Jie; Su, Jiangtao; Deng, Yuanyong [Key Laboratory of Solar Activity, National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012 (China); Priest, E. R., E-mail: chenjie@bao.ac.cn [Mathematical Institute, University of St Andrews, North Haugh, St Andrews, KY16 9SS (United Kingdom)

    2017-05-01

    Jets often occur repeatedly from almost the same location. In this paper, a complex solar jet was observed with two phases to the west of NOAA AR 11513 on 2012 July 2. If it had been observed at only moderate resolution, the two phases and their points of origin would have been regarded as identical. However, at high resolution we find that the two phases merge into one another and the accompanying footpoint brightenings occur at different locations. The phases originate from different magnetic patches rather than being one phase originating from the same patch. Photospheric line of sight (LOS) magnetograms show that the bases of the two phases lie in two different patches of magnetic flux that decrease in size during the occurrence of the two phases. Based on these observations, we suggest that the driving mechanism of the two successive phases is magnetic cancellation of two separate magnetic fragments with an opposite-polarity fragment between them.

  14. Sphingosine-1-phosphate (S1P) displays sustained S1P1 receptor agonism and signaling through S1P lyase-dependent receptor recycling.

    Science.gov (United States)

    Gatfield, John; Monnier, Lucile; Studer, Rolf; Bolli, Martin H; Steiner, Beat; Nayler, Oliver

    2014-07-01

    The sphingosine-1-phosphate (S1P) type 1 receptor (S1P1R) is a novel therapeutic target in lymphocyte-mediated autoimmune diseases. S1P1 receptor desensitization caused by synthetic S1P1 receptor agonists prevents T-lymphocyte egress from secondary lymphoid organs into the circulation. The selective S1P1 receptor agonist ponesimod, which is in development for the treatment of autoimmune diseases, efficiently reduces peripheral lymphocyte counts and displays efficacy in animal models of autoimmune disease. Using ponesimod and the natural ligand S1P, we investigated the molecular mechanisms leading to different signaling, desensitization and trafficking behavior of S1P1 receptors. In recombinant S1P1 receptor-expressing cells, ponesimod and S1P triggered Gαi protein-mediated signaling and β-arrestin recruitment with comparable potency and efficiency, but only ponesimod efficiently induced intracellular receptor accumulation. In human umbilical vein endothelial cells (HUVEC), ponesimod and S1P triggered translocation of the endogenous S1P1 receptor to the Golgi compartment. However, only ponesimod treatment caused efficient surface receptor depletion, receptor accumulation in the Golgi and degradation. Impedance measurements in HUVEC showed that ponesimod induced only short-lived Gαi protein-mediated signaling followed by resistance to further stimulation, whereas S1P induced sustained Gαi protein-mediated signaling without desensitization. Inhibition of S1P lyase activity in HUVEC rendered S1P an efficient S1P1 receptor internalizing compound and abrogated S1P-mediated sustained signaling. This suggests that S1P lyase - by facilitating S1P1 receptor recycling - is essential for S1P-mediated sustained signaling, and that synthetic agonists are functional antagonists because they are not S1P lyase substrates. Copyright © 2014 Elsevier Inc. All rights reserved.

  15. Phases of Ca from first principles

    International Nuclear Information System (INIS)

    Qiu, S L; Marcus, P M

    2009-01-01

    Structures and properties of many of the phases of Ca under pressure are calculated from first principles by a systematic procedure that minimizes total energy E with respect to structure under the constraint of constant volume V. The minima of E are followed on successive sweeps of lattice parameters for 11 of 14 Bravais symmetries for one-atom-per-cell structures. The structures include the four orthorhombic phases. Also included are the hexagonal close-packed and cubic diamond phases with two atoms per primitive cell. No uniquely orthorhombic phases are found; all one-atom orthorhombic phases over a mega-bar pressure range are identical to higher-symmetry phases. The simple cubic phase is shown to be stable where it is the ground state. The number of distinct one-atom phases reduces to five plus the two two-atom phases. For each of these phases the Gibbs free energy at pressure p, G(p), is calculated for a non-vibrating lattice; the functions G(p) give the ground state at each p, the relative stabilities of all phases and the thermodynamic phase transition pressures for all phase transitions over a several-megabar range.

  16. Generic two-phase coexistence in the quadratic contact process

    Energy Technology Data Exchange (ETDEWEB)

    Guo, Xiaofang [Iowa State Univ., Ames, IA (United States)

    2009-01-01

    This thesis focuses on the demonstration of the existence of and analysis of phenomena related to the discontinuous non-equilibrium phase transition between an active (or reactive) state and a poisoned (or extinguished) state occurring in a stochastic lattice-gas realization of Schloegl’s second model for autocatalysis.

  17. Electronic structure and physical properties of the spinel-type phase of BeP2N4 from all-electron density functional calculations

    International Nuclear Information System (INIS)

    Ching, W. Y.; Aryal, Sitram; Rulis, Paul; Schnick, Wolfgang

    2011-01-01

    Using density-functional-theory-based ab initio methods, the electronic structure and physical properties of the newly synthesized nitride BeP 2 N 4 with a phenakite-type structure and the predicted high-pressure spinel phase of BeP 2 N 4 are studied in detail. It is shown that both polymorphs are wide band-gap semiconductors with relatively small electron effective masses at the conduction-band minima. The spinel-type phase is more covalently bonded due to the increased number of P-N bonds for P at the octahedral sites. Calculations of mechanical properties indicate that the spinel-type polymorph is a promising superhard material with notably large bulk, shear, and Young's moduli. Also calculated are the Be K, P K, P L 3 , and N K edges of the electron energy-loss near-edge structure for both phases. They show marked differences because of the different local environments of the atoms in the two crystalline polymorphs. These differences will be very useful for the experimental identification of the products of high-pressure syntheses targeting the predicted spinel-type phase of BeP 2 N 4 .

  18. Simulation of the phenomenon of single-phase and two-phase natural circulation; Simulacao do fenomeno de circulacao natural mono e bifasica

    Energy Technology Data Exchange (ETDEWEB)

    Castrillo, Lazara Silveira

    1998-02-01

    Natural convection phenomenon is often used to remove the residual heat from the surfaces of bodies where the heat is generated e.g. during accidents or transients of nuclear power plants. Experimental study of natural circulation can be done in small scale experimental circuits and the results can be extrapolated for larger operational facilities. The numerical analysis of transients can be carried out by using large computational codes that simulate the thermohydraulic behavior in such facilities. The computational code RELAP5/MOD2, (Reactor Excursion and Leak Analysis Program) was developed by U.S. Nuclear Regulatory Commissions's. Division of Reactor Safety Research with the objective of analysis of transients and postulated accidents in the light water reactor (LWR) systems, including small and large ruptures with loss of coolant accidents (LOCA's). The results obtained by the simulation of single-phase and two-phase natural circulation, using the RELAP5/MOD2, are presented in this work. The study was carried out using the experimental circuit built at the 'Departamento de Engenharia Quimica da Escola Politecnica da Universidade de Sao Paulo'. In the circuit, two experiments were carried out with different conditions of power and mass flow, obtaining a single-phase regime with a level of power of 4706 W and flow of 5.10{sup -5} m{sup 3}/s (3 l/min) and a two-phase regime with a level of power of 6536 W and secondary flow 2,33.10{sup -5} m{sup 3}/s (1,4 l/min). The study allowed tio evaluate the capacity of the code for representing such phenomena as well as comparing the transients obtained theoretically with the experimental results. The comparative analysis shows that the code represents fairly well the single-phase transient, but the results for two-phase transients, starting from the nodalization and calibration used for the case single-phase transient, did not reproduce faithfully some experimental results. (author)

  19. Study of astrophysically important resonant states in 30 S using the 32S(p,t30 S reaction

    Directory of Open Access Journals (Sweden)

    Wrede C.

    2010-03-01

    Full Text Available A small fraction (< 1% of presolar SiC grains is suggested to have been formed in the ejecta of classical novae. The 29P(p,γ30S reaction plays an important role in understanding the Si isotopic abundances in such grains, which in turn provide us with information on the nature of the probable white dwarf progenitor’s core, as well as the peak temperatures achieved during nova outbursts, and thus the nova nucleosynthetic path. The 29P(p,γ30S reaction rate at nova temperatures is determined by two low-lying 3+ and 2+ resonances above the proton threshold at 4399 keV in 30S. Despite several experimental studies in the past, however, only one of these two states has only been observed very recently. We have studied the 30S nuclear structure via the 32S(p,t 30S reaction at 5 laboratory angles between 9° to 62°. We have observed 14 states, eleven of which are above the proton threshold, including two levels at 4692.7 ± 4.5 keV and 4813.8 ± 3.4 keV that are candidates for the 3+ and the previously “issing” 2+ state, respectively.

  20. Qualitative behaviour of incompressible two-phase flows with phase ...

    Indian Academy of Sciences (India)

    Jan Prüss

    2017-11-07

    Nov 7, 2017 ... Qualitative behaviour of incompressible two-phase flows with phase ... Germany. 2Graduate School of Human and Environmental Studies, Kyoto University, ... Note that j is a dummy variable as it can be eliminated from the ...

  1. Characterizing the correlations between local phase fractions of gas-liquid two-phase flow with wire-mesh sensor.

    Science.gov (United States)

    Tan, C; Liu, W L; Dong, F

    2016-06-28

    Understanding of flow patterns and their transitions is significant to uncover the flow mechanics of two-phase flow. The local phase distribution and its fluctuations contain rich information regarding the flow structures. A wire-mesh sensor (WMS) was used to study the local phase fluctuations of horizontal gas-liquid two-phase flow, which was verified through comparing the reconstructed three-dimensional flow structure with photographs taken during the experiments. Each crossing point of the WMS is treated as a node, so the measurement on each node is the phase fraction in this local area. An undirected and unweighted flow pattern network was established based on connections that are formed by cross-correlating the time series of each node under different flow patterns. The structure of the flow pattern network reveals the relationship of the phase fluctuations at each node during flow pattern transition, which is then quantified by introducing the topological index of the complex network. The proposed analysis method using the WMS not only provides three-dimensional visualizations of the gas-liquid two-phase flow, but is also a thorough analysis for the structure of flow patterns and the characteristics of flow pattern transition. This article is part of the themed issue 'Supersensing through industrial process tomography'. © 2016 The Author(s).

  2. Synchronization of S phase in Schizosaccharomyces pombe cells by transient exposure to M-factor pheromone

    DEFF Research Database (Denmark)

    Nielsen, Olaf

    2016-01-01

    A well-characterized S phase, a unicellular lifestyle, and a plethora of mutations in key components of DNA metabolism make fission yeast a particularly attractive system in which to study DNA replication. However, synchronization of passage through a normal S phase has proved challenging. This p....... This protocol describes how combining nitrogen starvation with M-factor mating pheromone treatment presents a highly effective method for synchronizing passage through an ostensibly normal S phase....

  3. Phase separation and shape deformation of two-phase membranes

    International Nuclear Information System (INIS)

    Jiang, Y.; Lookman, T.; Saxena, A.

    2000-01-01

    Within a coupled-field Ginzburg-Landau model we study analytically phase separation and accompanying shape deformation on a two-phase elastic membrane in simple geometries such as cylinders, spheres, and tori. Using an exact periodic domain wall solution we solve for the shape and phase separating field, and estimate the degree of deformation of the membrane. The results are pertinent to preferential phase separation in regions of differing curvature on a variety of vesicles. (c) 2000 The American Physical Society

  4. Frictional pressure drop of steam-water two-phase flow in helical coils with small helix diameter of HTR-10

    International Nuclear Information System (INIS)

    Bi Qincheng; Chen Tingkuan; Luo Yushan; Zheng Jianxue

    1996-01-01

    Experiments of steam-water two-phase flow frictional pressure drop through five vertically and horizontally positioned helical coils were carried out in the high pressure steam water test loop of Xi'an Jiaotong University. Two kinds of tube with inner diameters of 10 mm and 12 mm were used to form the coils. The helix diameter was 115 mm with coil pitch 22.5 mm. The experimental conditions were: pressure p = 4-14 MPa, mass velocity G = 400-2000 kg/(m 2 ·s), and inner wall heat flux q = 0-750 kW/m 2 . Theoretical analysis with a semi-empirical correlation was made to predict the two-phase flow fictional pressure drop through these kinds of helical coils

  5. Experimental Study about Two-phase Damping Ratio on a Tube Bundle Subjected to Homogeneous Two-phase Flow

    Energy Technology Data Exchange (ETDEWEB)

    Sim, Woo Gun; Dagdan, Banzragch [Hannam Univ., Daejeon (Korea, Republic of)

    2017-03-15

    Two-phase cross flow exists in many shell-and-tube heat exchangers such as condensers, evaporators, and nuclear steam generators. The drag force acting on a tube bundle subjected to air/water flow is evaluated experimentally. The cylinders subjected to two-phase flow are arranged in a normal square array. The ratio of pitch to diameter is 1.35, and the diameter of the cylinder is 18 mm. The drag force along the flow direction on the tube bundles is measured to calculate the drag coefficient and the two-phase damping ratio. The two-phase damping ratios, given by the analytical model for a homogeneous two-phase flow, are compared with experimental results. The correlation factor between the frictional pressure drop and the hydraulic drag coefficient is determined from the experimental results. The factor is used to calculate the drag force analytically. It is found that with an increase in the mass flux, the drag force, and the drag coefficients are close to the results given by the homogeneous model. The result shows that the damping ratio can be calculated using the homogeneous model for bubbly flow of sufficiently large mass flux.

  6. The effect of spontaneous curvature on a two-phase vesicle

    International Nuclear Information System (INIS)

    Cox, Geoffrey; Lowengrub, John

    2015-01-01

    Vesicles are membrane-bound structures commonly known for their roles in cellular transport and the shape of a vesicle is determined by its surrounding membrane (lipid bilayer). When the membrane is composed of different lipids, it is natural for the lipids of similar molecular structure to migrate towards one another (via spinodal decomposition), creating a multi-phase vesicle. In this article, we consider a two-phase vesicle model which is driven by nature's propensity to maintain a minimal state of elastic energy. The model assumes a continuum limit, thereby treating the membrane as a closed three-dimensional surface. The main purpose of this study is to reveal the complexity of the Helfrich two-phase vesicle model with non-zero spontaneous curvature and provide further evidence to support the relevance of spontaneous curvature as a modelling parameter. In this paper, we illustrate the complexity of the Helfrich two-phase model by providing multiple examples of undocumented solutions and energy hysteresis. We also investigate the influence of spontaneous curvature on morphological effects and membrane phenomena such as budding and fusion. (paper)

  7. Prediction of pressure drop and CCFL breakdown in countercurrent two-phase flow

    International Nuclear Information System (INIS)

    Ostrogorsky, A.G.; Gay, R.R.; Lahey, R.T. Jr.

    1983-01-01

    A steady-state analytical has been developed to predict channel pressure drop as a function of inlet vapor flow rate and applied heat flux during conditions of countercurrent two-phase flow. The interfacial constitutive relations utilized are flow surface dependent and allow for the existence of either smooth or way liquid films. A computer code was developed to solve the analytical model. Predictions of Δp versus vapor flow rate were found to agree favorably with experimental data from adiabatic, air/water systems. In addition, the model was used to predict countercurrent flow conditions in heated channels characteristic of a BWR/4 nuclear reactor fuel assembly

  8. Hydrodynamic characteristics of a two-phase gas-liquid flow upward through a fixed bed of spherical particles

    Directory of Open Access Journals (Sweden)

    VELIZAR D. STANKOVIC

    2001-01-01

    Full Text Available The influence of an electrochemically generated gas phase on the hydrodynamic characteristics of a three-phase system has been examined. The two-phase fluid, (gas-liquid, in which the liquid phase is the continuous one, flows through a packed bed with glass spheres. The influence of the liquid velocity was examined, as well as the gas velocity and particle diameter on the pressure drop through the fixed bed. It was found that with increasing liquid velocity (wl = 0.0162–0.03 m/s, the relative pressure drop decreases through the fixed bed. With increasing current density, the pressure drop increases, since greater gas quantities stay behind in the fixed bed. Besides, it was found that with decreasing diameter of the glass particles, the relative pressure drop also decreases. The relationship betweeen the experimentally obtained friction factor and the Reynolds number was established.

  9. Potencial evocado auditivo tardio relacionado a eventos (P300 na síndrome de Down Late auditory event-related evoked potential (P300 in Down's syndrome patients

    Directory of Open Access Journals (Sweden)

    Carla Patrícia Hernandez Alves Ribeiro César

    2010-04-01

    Full Text Available A síndrome de Down é causada pela trissomia do cromossomo 21 e está associada com alteração do processamento auditivo, distúrbio de aprendizagem e, provavelmente, início precoce de Doença de Alzheimer. OBJETIVO: Avaliar as latências e amplitudes do potencial evocado auditivo tardio relacionado a eventos (P300 e suas alterações em indivíduos jovens adultos com síndrome de Down. MATERIAL E MÉTODO: Estudo de caso prospectivo. Latências e amplitudes do P300 foram avaliadas em 17 indivíduos com síndrome de Down e 34 indivíduos sadios. RESULTADOS: Foram identificadas latências do P300 (N1, P2, N2 e P3 prolongadas e amplitude N2 - P3 diminuída nos indivíduos com síndrome de Down quando comparados ao grupo controle. CONCLUSÃO: Em indivíduos jovens adultos com síndrome de Down ocorre aumento das latências N1, P2, N2 e P3, e diminuição significativa da amplitude N2-P3 do potencial evocado auditivo tardio relacionado a eventos (P300, sugerindo prejuízo da integração da área de associação auditiva com as áreas corticais e subcorticais do sistema nervoso central.Down syndrome is caused by a trisomy of chromosome 21 and is associated with central auditory processing deficit, learning disability and, probably, early-onset Alzheimer's disease. AIM: to evaluate the latencies and amplitudes of evoked late auditory potential related to P300 events and their changes in young adults with Down's syndrome. MATERIALS AND METHODS: Prospective case study. P300 test latency and amplitudes were evaluated in 17 individuals with Down's syndrome and 34 healthy individuals. RESULTS The P300 latency (N1, P2, N2 and P3 was longer and the N2-P3 amplitude was lower in individuals with Down syndrome when compared to those in the control group. CONCLUSION: In young adults with Down syndrome, N1, P2, N2 and P3 latencies of late auditory evoked potential related to P300 events were prolonged, and N2 - P3 amplitudes were significantly reduced

  10. Two-state thermodynamics and the possibility of a liquid-liquid phase transition in supercooled TIP4P/2005 water

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Rakesh S.; Debenedetti, Pablo G. [Department of Chemical & Biological Engineering, Princeton University, Princeton, New Jersey 08544 (United States); Biddle, John W.; Anisimov, Mikhail A., E-mail: anisimov@umd.edu [Institute of Physical Science and Technology and Department of Chemical and Biomolecular Engineering, University of Maryland, College Park, Maryland 20742 (United States)

    2016-04-14

    Water shows intriguing thermodynamic and dynamic anomalies in the supercooled liquid state. One possible explanation of the origin of these anomalies lies in the existence of a metastable liquid-liquid phase transition (LLPT) between two (high and low density) forms of water. While the anomalies are observed in experiments on bulk and confined water and by computer simulation studies of different water-like models, the existence of a LLPT in water is still debated. Unambiguous experimental proof of the existence of a LLPT in bulk supercooled water is hampered by fast ice nucleation which is a precursor of the hypothesized LLPT. Moreover, the hypothesized LLPT, being metastable, in principle cannot exist in the thermodynamic limit (infinite size, infinite time). Therefore, computer simulations of water models are crucial for exploring the possibility of the metastable LLPT and the nature of the anomalies. In this work, we present new simulation results in the NVT ensemble for one of the most accurate classical molecular models of water, TIP4P/2005. To describe the computed properties and explore the possibility of a LLPT, we have applied two-structure thermodynamics, viewing water as a non-ideal mixture of two interconvertible local structures (“states”). The results suggest the presence of a liquid-liquid critical point and are consistent with the existence of a LLPT in this model for the simulated length and time scales. We have compared the behavior of TIP4P/2005 with other popular water-like models, namely, mW and ST2, and with real water, all of which are well described by two-state thermodynamics. In view of the current debate involving different studies of TIP4P/2005, we discuss consequences of metastability and finite size in observing the liquid-liquid separation. We also address the relationship between the phenomenological order parameter of two-structure thermodynamics and the microscopic nature of the low-density structure.

  11. Two-state thermodynamics and the possibility of a liquid-liquid phase transition in supercooled TIP4P/2005 water

    International Nuclear Information System (INIS)

    Singh, Rakesh S.; Debenedetti, Pablo G.; Biddle, John W.; Anisimov, Mikhail A.

    2016-01-01

    Water shows intriguing thermodynamic and dynamic anomalies in the supercooled liquid state. One possible explanation of the origin of these anomalies lies in the existence of a metastable liquid-liquid phase transition (LLPT) between two (high and low density) forms of water. While the anomalies are observed in experiments on bulk and confined water and by computer simulation studies of different water-like models, the existence of a LLPT in water is still debated. Unambiguous experimental proof of the existence of a LLPT in bulk supercooled water is hampered by fast ice nucleation which is a precursor of the hypothesized LLPT. Moreover, the hypothesized LLPT, being metastable, in principle cannot exist in the thermodynamic limit (infinite size, infinite time). Therefore, computer simulations of water models are crucial for exploring the possibility of the metastable LLPT and the nature of the anomalies. In this work, we present new simulation results in the NVT ensemble for one of the most accurate classical molecular models of water, TIP4P/2005. To describe the computed properties and explore the possibility of a LLPT, we have applied two-structure thermodynamics, viewing water as a non-ideal mixture of two interconvertible local structures (“states”). The results suggest the presence of a liquid-liquid critical point and are consistent with the existence of a LLPT in this model for the simulated length and time scales. We have compared the behavior of TIP4P/2005 with other popular water-like models, namely, mW and ST2, and with real water, all of which are well described by two-state thermodynamics. In view of the current debate involving different studies of TIP4P/2005, we discuss consequences of metastability and finite size in observing the liquid-liquid separation. We also address the relationship between the phenomenological order parameter of two-structure thermodynamics and the microscopic nature of the low-density structure.

  12. Obtaining of Analytical Relations for Hydraulic Parameters of Channels With Two Phase Flow Using Open CFD Toolbox

    Science.gov (United States)

    Varseev, E.

    2017-11-01

    The present work is dedicated to verification of numerical model in standard solver of open-source CFD code OpenFOAM for two-phase flow simulation and to determination of so-called “baseline” model parameters. Investigation of heterogeneous coolant flow parameters, which leads to abnormal friction increase of channel in two-phase adiabatic “water-gas” flows with low void fractions, presented.

  13. Two-Phase Immiscible Flows in Porous Media: The Mesocopic Maxwell–Stefan Approach

    DEFF Research Database (Denmark)

    Shapiro, Alexander

    2015-01-01

    We develop an approach to coupling between viscous flows of the two phases in porous media, based on the Maxwell–Stefan formalism. Two versions of the formalism are presented: the general form, and the form based on the interaction of the flowing phases with the interface between them. The last...... of mixing” between the flowing phases. Comparison to the available experimental data on the steady-state two-phase relative permeabilities is presented....... approach is supported by the description of the flow on the mesoscopic level, as coupled boundary problems for the Brinkmann or Stokes equations. It becomes possible, in some simplifying geometric assumptions, to derive exact expressions for the phenomenological coefficients in the Maxwell–Stefan transport...

  14. SMC1-Mediated Intra-S-Phase Arrest Facilitates Bocavirus DNA Replication

    Science.gov (United States)

    Luo, Yong; Deng, Xuefeng; Cheng, Fang; Li, Yi

    2013-01-01

    Activation of a host DNA damage response (DDR) is essential for DNA replication of minute virus of canines (MVC), a member of the genus Bocavirus of the Parvoviridae family; however, the mechanism by which DDR contributes to viral DNA replication is unknown. In the current study, we demonstrate that MVC infection triggers the intra-S-phase arrest to slow down host cellular DNA replication and to recruit cellular DNA replication factors for viral DNA replication. The intra-S-phase arrest is regulated by ATM (ataxia telangiectasia-mutated kinase) signaling in a p53-independent manner. Moreover, we demonstrate that SMC1 (structural maintenance of chromosomes 1) is the key regulator of the intra-S-phase arrest induced during infection. Either knockdown of SMC1 or complementation with a dominant negative SMC1 mutant blocks both the intra-S-phase arrest and viral DNA replication. Finally, we show that the intra-S-phase arrest induced during MVC infection was caused neither by damaged host cellular DNA nor by viral proteins but by replicating viral genomes physically associated with the DNA damage sensor, the Mre11-Rad50-Nbs1 (MRN) complex. In conclusion, the feedback loop between MVC DNA replication and the intra-S-phase arrest is mediated by ATM-SMC1 signaling and plays a critical role in MVC DNA replication. Thus, our findings unravel the mechanism underlying DDR signaling-facilitated MVC DNA replication and demonstrate a novel strategy of DNA virus-host interaction. PMID:23365434

  15. First evidence for the two-body charmless baryonic decay $B^0 \\to p \\bar{p}$

    CERN Document Server

    INSPIRE-00258707; Adeva, B; Adinolfi, M; Adrover, C; Affolder, A; Ajaltouni, Z; Albrecht, J; Alessio, F; Alexander, M; Ali, S; Alkhazov, G; Alvarez Cartelle, P; Alves Jr, A A; Amato, S; Amerio, S; Amhis, Y; Anderlini, L; Anderson, J; Andreassen, R; Andrews, J E; Appleby, R B; Aquines Gutierrez, O; Archilli, F; Artamonov, A; Artuso, M; Aslanides, E; Auriemma, G; Baalouch, M; Bachmann, S; Back, J J; Baesso, C; Balagura, V; Baldini, W; Barlow, R J; Barschel, C; Barsuk, S; Barter, W; Bauer, Th; Bay, A; Beddow, J; Bedeschi, F; Bediaga, I; Belogurov, S; Belous, K; Belyaev, I; Ben-Haim, E; Bencivenni, G; Benson, S; Benton, J; Berezhnoy, A; Bernet, R; Bettler, M -O; van Beuzekom, M; Bien, A; Bifani, S; Bird, T; Bizzeti, A; Bjørnstad, P M; Blake, T; Blanc, F; Blouw, J; Blusk, S; Bocci, V; Bondar, A; Bondar, N; Bonivento, W; Borghi, S; Borgia, A; Bowcock, T J V; Bowen, E; Bozzi, C; Brambach, T; van den Brand, J; Bressieux, J; Brett, D; Britsch, M; Britton, T; Brook, N H; Brown, H; Burducea, I; Bursche, A; Busetto, G; Buytaert, J; Cadeddu, S; Callot, O; Calvi, M; Calvo Gomez, M; Camboni, A; Campana, P; Campora Perez, D; Carbone, A; Carboni, G; Cardinale, R; Cardini, A; Carranza-Mejia, H; Carson, L; Carvalho Akiba, K; Casse, G; Castillo Garcia, L; Cattaneo, M; Cauet, Ch; Cenci, R; Charles, M; Charpentier, Ph; Chen, P; Chiapolini, N; Chrzaszcz, M; Ciba, K; Cid Vidal, X; Ciezarek, G; Clarke, P E L; Clemencic, M; Cliff, H V; Closier, J; Coca, C; Coco, V; Cogan, J; Cogneras, E; Collins, P; Comerma-Montells, A; Contu, A; Cook, A; Coombes, M; Coquereau, S; Corti, G; Couturier, B; Cowan, G A; Cowie, E; Craik, D C; Cunliffe, S; Currie, R; D'Ambrosio, C; David, P; David, P N Y; Davis, A; De Bonis, I; De Bruyn, K; De Capua, S; De Cian, M; De Miranda, J M; De Paula, L; De Silva, W; De Simone, P; Decamp, D; Deckenhoff, M; Del Buono, L; Déléage, N; Derkach, D; Deschamps, O; Dettori, F; Di Canto, A; Dijkstra, H; Dogaru, M; Donleavy, S; Dordei, F; Dosil Suárez, A; Dossett, D; Dovbnya, A; Dupertuis, F; Durante, P; Dzhelyadin, R; Dziurda, A; Dzyuba, A; Easo, S; Egede, U; Egorychev, V; Eidelman, S; van Eijk, D; Eisenhardt, S; Eitschberger, U; Ekelhof, R; Eklund, L; El Rifai, I; Elsasser, Ch; Falabella, A; Färber, C; Fardell, G; Farinelli, C; Farry, S; Ferguson, D; Fernandez Albor, V; Ferreira Rodrigues, F; Ferro-Luzzi, M; Filippov, S; Fiore, M; Fitzpatrick, C; Fontana, M; Fontanelli, F; Forty, R; Francisco, O; Frank, M; Frei, C; Frosini, M; Furcas, S; Furfaro, E; Gallas Torreira, A; Galli, D; Gandelman, M; Gandini, P; Gao, Y; Garofoli, J; Garosi, P; Garra Tico, J; Garrido, L; Gaspar, C; Gauld, R; Gersabeck, E; Gersabeck, M; Gershon, T; Ghez, Ph; Gibson, V; Giubega, L; Gligorov, V V; Göbel, C; Golubkov, D; Golutvin, A; Gomes, A; Gorbounov, P; Gordon, H; Gotti, C; Grabalosa Gándara, M; Graciani Diaz, R; Granado Cardoso, L A; Graugés, E; Graziani, G; Grecu, A; Greening, E; Gregson, S; Griffith, P; Grünberg, O; Gui, B; Gushchin, E; Guz, Yu; Gys, T; Hadjivasiliou, C; Haefeli, G; Haen, C; Haines, S C; Hall, S; Hamilton, B; Hampson, T; Hansmann-Menzemer, S; Harnew, N; Harnew, S T; Harrison, J; Hartmann, T; He, J; Head, T; Heijne, V; Hennessy, K; Henrard, P; Hernando Morata, J A; van Herwijnen, E; Hess, M; Hicheur, A; Hicks, E; Hill, D; Hoballah, M; Hombach, C; Hopchev, P; Hulsbergen, W; Hunt, P; Huse, T; Hussain, N; Hutchcroft, D; Hynds, D; Iakovenko, V; Idzik, M; Ilten, P; Jacobsson, R; Jaeger, A; Jans, E; Jaton, P; Jawahery, A; Jing, F; John, M; Johnson, D; Jones, C R; Joram, C; Jost, B; Kaballo, M; Kandybei, S; Kanso, W; Karacson, M; Karbach, T M; Kenyon, I R; Ketel, T; Keune, A; Khanji, B; Kochebina, O; Komarov, I; Koopman, R F; Koppenburg, P; Korolev, M; Kozlinskiy, A; Kravchuk, L; Kreplin, K; Kreps, M; Krocker, G; Krokovny, P; Kruse, F; Kucharczyk, M; Kudryavtsev, V; Kurek, K; Kvaratskheliya, T; La Thi, V N; Lacarrere, D; Lafferty, G; Lai, A; Lambert, D; Lambert, R W; Lanciotti, E; Lanfranchi, G; Langenbruch, C; Latham, T; Lazzeroni, C; Le Gac, R; van Leerdam, J; Lees, J -P; Lefèvre, R; Leflat, A; Lefrançois, J; Leo, S; Leroy, O; Lesiak, T; Leverington, B; Li, Y; Li Gioi, L; Liles, M; Lindner, R; Linn, C; Liu, B; Liu, G; Lohn, S; Longstaff, I; Lopes, J H; Lopez-March, N; Lu, H; Lucchesi, D; Luisier, J; Luo, H; Machefert, F; Machikhiliyan, I V; Maciuc, F; Maev, O; Malde, S; Manca, G; Mancinelli, G; Maratas, J; Marconi, U; Marino, P; Märki, R; Marks, J; Martellotti, G; Martens, A; Martín Sánchez, A; Martinelli, M; Martinez Santos, D; Martins Tostes, D; Martynov, A; Massafferri, A; Matev, R; Mathe, Z; Matteuzzi, C; Maurice, E; Mazurov, A; McCarthy, J; McNab, A; McNulty, R; McSkelly, B; Meadows, B; Meier, F; Meissner, M; Merk, M; Milanes, D A; Minard, M -N; Molina Rodriguez, J; Monteil, S; Moran, D; Morawski, P; Mordà, A; Morello, M J; Mountain, R; Mous, I; Muheim, F; Müller, K; Muresan, R; Muryn, B; Muster, B; Naik, P; Nakada, T; Nandakumar, R; Nasteva, I; Needham, M; Neubert, S; Neufeld, N; Nguyen, A D; Nguyen, T D; Nguyen-Mau, C; Nicol, M; Niess, V; Niet, R; Nikitin, N; Nikodem, T; Nomerotski, A; Novoselov, A; Oblakowska-Mucha, A; Obraztsov, V; Oggero, S; Ogilvy, S; Okhrimenko, O; Oldeman, R; Orlandea, M; Otalora Goicochea, J M; Owen, P; Oyanguren, A; Pal, B K; Palano, A; Palczewski, T; Palutan, M; Panman, J; Papanestis, A; Pappagallo, M; Parkes, C; Parkinson, C J; Passaleva, G; Patel, G D; Patel, M; Patrick, G N; Patrignani, C; Pavel-Nicorescu, C; Pazos Alvarez, A; Pellegrino, A; Penso, G; Pepe Altarelli, M; Perazzini, S; Perez Trigo, E; Pérez-Calero Yzquierdo, A; Perret, P; Perrin-Terrin, M; Pescatore, L; Pesen, E; Petridis, K; Petrolini, A; Phan, A; Picatoste Olloqui, E; Pietrzyk, B; Pilař, T; Pinci, D; Playfer, S; Plo Casasus, M; Polci, F; Polok, G; Poluektov, A; Polycarpo, E; Popov, A; Popov, D; Popovici, B; Potterat, C; Powell, A; Prisciandaro, J; Pritchard, A; Prouve, C; Pugatch, V; Puig Navarro, A; Punzi, G; Qian, W; Rademacker, J H; Rakotomiaramanana, B; Rangel, M S; Raniuk, I; Rauschmayr, N; Raven, G; Redford, S; Reid, M M; dos Reis, A C; Ricciardi, S; Richards, A; Rinnert, K; Rives Molina, V; Roa Romero, D A; Robbe, P; Roberts, D A; Rodrigues, E; Rodriguez Perez, P; Roiser, S; Romanovsky, V; Romero Vidal, A; Rouvinet, J; Ruf, T; Ruffini, F; Ruiz, H; Ruiz Valls, P; Sabatino, G; Saborido Silva, J J; Sagidova, N; Sail, P; Saitta, B; Salustino Guimaraes, V; Sanmartin Sedes, B; Sannino, M; Santacesaria, R; Santamarina Rios, C; Santovetti, E; Sapunov, M; Sarti, A; Satriano, C; Satta, A; Savrie, M; Savrina, D; Schaack, P; Schiller, M; Schindler, H; Schlupp, M; Schmelling, M; Schmidt, B; Schneider, O; Schopper, A; Schune, M -H; Schwemmer, R; Sciascia, B; Sciubba, A; Seco, M; Semennikov, A; Senderowska, K; Sepp, I; Serra, N; Serrano, J; Seyfert, P; Shapkin, M; Shapoval, I; Shatalov, P; Shcheglov, Y; Shears, T; Shekhtman, L; Shevchenko, O; Shevchenko, V; Shires, A; Silva Coutinho, R; Sirendi, M; Skidmore, N; Skwarnicki, T; Smith, N A; Smith, E; Smith, J; Smith, M; Sokoloff, M D; Soler, F J P; Soomro, F; Souza, D; Souza De Paula, B; Spaan, B; Sparkes, A; Spradlin, P; Stagni, F; Stahl, S; Steinkamp, O; Stevenson, S; Stoica, S; Stone, S; Storaci, B; Straticiuc, M; Straumann, U; Subbiah, V K; Sun, L; Swientek, S; Syropoulos, V; Szczekowski, M; Szczypka, P; Szumlak, T; T'Jampens, S; Teklishyn, M; Teodorescu, E; Teubert, F; Thomas, C; Thomas, E; van Tilburg, J; Tisserand, V; Tobin, M; Tolk, S; Tonelli, D; Topp-Joergensen, S; Torr, N; Tournefier, E; Tourneur, S; Tran, M T; Tresch, M; Tsaregorodtsev, A; Tsopelas, P; Tuning, N; Ubeda Garcia, M; Ukleja, A; Urner, D; Ustyuzhanin, A; Uwer, U; Vagnoni, V; Valenti, G; Vallier, A; Van Dijk, M; Vazquez Gomez, R; Vazquez Regueiro, P; Vázquez Sierra, C; Vecchi, S; Velthuis, J J; Veltri, M; Veneziano, G; Vesterinen, M; Viaud, B; Vieira, D; Vilasis-Cardona, X; Vollhardt, A; Volyanskyy, D; Voong, D; Vorobyev, A; Vorobyev, V; Voß, C; Voss, H; Waldi, R; Wallace, C; Wallace, R; Wandernoth, S; Wang, J; Ward, D R; Watson, N K; Webber, A D; Websdale, D; Whitehead, M; Wicht, J; Wiechczynski, J; Wiedner, D; Wiggers, L; Wilkinson, G; Williams, M P; Williams, M; Wilson, F F; Wimberley, J; Wishahi, J; Wislicki, W; Witek, M; Wotton, S A; Wright, S; Wu, S; Wyllie, K; Xie, Y; Xing, Z; Yang, Z; Young, R; Yuan, X; Yushchenko, O; Zangoli, M; Zavertyaev, M; Zhang, F; Zhang, L; Zhang, W C; Zhang, Y; Zhelezov, A; Zhokhov, A; Zhong, L; Zvyagin, A

    2013-01-01

    The results of a search for the rare two-body charmless baryonic decays $B^0 \\to p \\bar{p}$ and $B_s^0 \\to p \\bar{p}$ are reported. The analysis uses a data sample, corresponding to an integrated luminosity of 0.9 fb$^{-1}$, of $pp$ collision data collected by the LHCb experiment at a centre-of-mass energy of 7 TeV. An excess of $B^0 \\to p \\bar{p}$ candidates with respect to background expectations is seen with a statistical significance of 3.3 standard deviations. This is the first evidence for a two-body charmless baryonic $B^0$ decay. No significant $B_s^0 \\to p \\bar{p}$ signal is observed, leading to an improvement of three orders of magnitude over previous bounds. If the excess events are interpreted as signal, the 68.3\\% confidence level intervals on the branching fractions are \\begin{eqnarray} \\cal{B}(\\rm{B}^0 \\to p \\bar{p}) & = & ( 1.47 \\,^{+0.62}_{-0.51} \\,^{+0.35}_{-0.14} ) \\times 10^{-8} \\,, \

  16. Frictional pressure drop of gas liquid two-phase flow in pipes

    International Nuclear Information System (INIS)

    Shannak, Benbella A.

    2008-01-01

    Experiments of air water two-phase flow frictional pressure drop of vertical and horizontal smooth and relatively rough pipes were conducted, respectively. The result demonstrated that the frictional pressure drop increases with increasing relative roughness of the pipe. However, the influence of the relative roughness becomes more evident at higher vapour quality and higher mass flux. A new prediction model for frictional pressure drop of two-phase flow in pipes is proposed. The model includes a new definition of the Reynolds number and the friction factor of two-phase flow. The proposed model fits the presented experimental data very well, for vertical, horizontal, smooth and rough pipes. Therefore, the reproductive accuracy of the model is tested on the experimental data existing in the open literature and compared with the most common models. The statistical comparison, based on the Friedel's Data-Bank containing of about 16,000 measured data, demonstrated that the proposed model is the best overall agreement with the data. The model was tested for a wide range of flow types, fluid systems, physical properties and geometrical parameters, typically encountered in industrial piping systems. Hence, calculating based on the new approach is sufficiently accurate for engineering purposes

  17. Method of non-interacting thermodynamic calculation of binary phase diagrams containing p disordered phases with variable composition and q phases with constant composition at (p, q) ≤ 10

    International Nuclear Information System (INIS)

    Udovskij, A.L.; Karpushkin, V.N.; Nikishina, E.A.

    1991-01-01

    Method of non-interacting thermodynamic calculation of state diagram of binary systems contacting p disordered phases with variable composition and q phases with constant composition for (p, q) ≤ 10 case is developed. Determination of all possible solutions of phase equilibrium equations is realized in the method. Certain application examples of computer-realized method of T-x thermodynamic calculation using PC for Cr-W, Ni-W, Ni-Al, Ni-Re binary systems are given

  18. Ferrofluid-in-oil two-phase flow patterns in a flow-focusing microchannel

    Science.gov (United States)

    Sheu, T. S.; Chen, Y. T.; Lih, F. L.; Miao, J. M.

    This study investigates the two-phase flow formation process of water-based Fe3O4 ferrofluid (dispersed phase) in a silicon oil (continuous phase) flow in the microfluidic flow-focusing microchannel under various operational conditions. With transparent PDMS chip and optical microscope, four main two-phase flow patterns as droplet flow, slug flow, ring flow and churn flow are observed. The droplet shape, size, and formation mechanism were also investigated under different Ca numbers and intended to find out the empirical relations. The paper marks an original flow pattern map of the ferrofluid-in-oil flows in the microfluidic flow-focusing microchannels. The flow pattern transiting from droplet flow to slug flow appears for an operational conditions of QR < 1 and Lf / W < 1. The power law index that related Lf / W to QR was 0.36 in present device.

  19. Two-phase flow simulation of scour around a cylindrical pile

    Science.gov (United States)

    Nagel, T.; Chauchat, J.; Bonamy, C.; Liu, X.; Cheng, Z.; Hsu, T. J.

    2017-12-01

    Scour around structures is a major engineering issue that requires a detailed description of the flow field but also a consistent description of sediment transport processes that could not only be related to bed shear stress, like Shields parameter based sediment transport formula. In order to address this issue we used a multi-dimensional two-phase flow solver, sedFoam-2.0 (Chauchat et al., GMD 2017) implemented under the open-source CFD toolbox OpenFoam. Three-dimensional simulations have been performed on Roulund et al. (JFM 2005) configurations for clear-water and live bed cases. The k-omega model from Wilcox (AIAA Journal 2006) is used for the turbulent stress and the granular rheology μ(I) is used for the granular stress in the live bed case. The hydrodynamic is validated on the clear water case and the numerical results obtained for the live bed case provide a proof of concept that two-phase flow model is applicable to such problem with quantitative results for the prediction of scour depth upstream and downstream the cylinder at short timescales, up to 300s. Analyzing the simulation results in term of classical dimensionless sediment transport flux versus Shields parameter allows to get more insight into the fine scale sediment transport mechanisms involved in the scour process.

  20. Theoretical Prediction of Melting Relations in the Deep Mantle: the Phase Diagram Approach

    Science.gov (United States)

    Belmonte, D.; Ottonello, G. A.; Vetuschi Zuccolini, M.; Attene, M.

    2016-12-01

    Despite the outstanding progress in computer technology and experimental facilities, understanding melting phase relations in the deep mantle is still an open challenge. In this work a novel computational scheme to predict melting relations at HP-HT by a combination of first principles DFT calculations, polymer chemistry and equilibrium thermodynamics is presented and discussed. The adopted theoretical framework is physically-consistent and allows to compute multi-component phase diagrams relevant to Earth's deep interior in a broad range of P-T conditions by a convex-hull algorithm for Gibbs free energy minimisation purposely developed for high-rank simplexes. The calculated phase diagrams are in turn used as a source of information to gain new insights on the P-T-X evolution of magmas in the deep mantle, providing some thermodynamic constraints to both present-day and early Earth melting processes. High-pressure melting curves of mantle silicates are also obtained as by-product of phase diagram calculation. Application of the above method to the MgO-Al2O3-SiO2 (MAS) ternary system highlights as pressure effects are not only able to change the nature of melting of some minerals (like olivine and pyroxene) from eutectic to peritectic (and vice versa), but also simplify melting relations by drastically reducing the number of phases with a primary phase field at HP-HT conditions. It turns out that mineral phases like Majorite-Pyrope garnet and Anhydrous Phase B (Mg14Si5O24), which are often disregarded in modelling melting processes of mantle assemblages, are stable phases at solidus or liquidus conditions in a P-T range compatible with the mantle transition zone (i.e. P = 16 - 23 GPa and T = 2200 - 2700 °C) when their thermodynamic and thermophysical properties are properly assessed. Financial support to the Senior Author (D.B.) during his stay as Invited Scientist at the Institut de Physique du Globe de Paris (IPGP, Paris) is warmly acknowledged.

  1. Effects of S/V on secondary phase formation on waste glasses

    International Nuclear Information System (INIS)

    Feng, X.; Buck, E.C.; Bates, J.K.; Gong, M.; Dietz, N.L.; Pegg, I.L.

    1994-01-01

    Simulated West Valley high-level nuclear waste glass, WV205, was leached with and without buffered media in both deuterated and ordinary water at glass surface area to solution volumes (S/N) of 200--6000 m -1 . Examination of the glass surface after testing for 14 days indicated that the S/V-induced pH change plays a dominant role in the development of the altered surface layer and the secondary phases formed. The changes due to SN-induced pH determine the rate of surface layer formation, the element distribution in the surface layer, and possibly, the identities of the secondary phases. Changes due to SN-induced elemental concentration also influence glass reaction rate in terms of the layer thickness and the elemental distribution in the surface layers

  2. High-resolution two-photon spectroscopy of a 5 p56 p ←5 p6 transition of xenon

    Science.gov (United States)

    Altiere, Emily; Miller, Eric R.; Hayamizu, Tomohiro; Jones, David J.; Madison, Kirk W.; Momose, Takamasa

    2018-01-01

    We report high-resolution Doppler-free two-photon excitation spectroscopy of Xe from the ground state to the 5 p5(P 3 /2 2 ) 6 p [3 /2 ] 2 2 electronic excited state. This is a first step to developing a comagnetometer using polarized 129Xe atoms for planned neutron electric dipole moment measurements at TRIUMF. Narrow linewidth radiation at 252.5 nm produced by a continuous wave laser was built up in an optical cavity to excite the two-photon transition, and the near-infrared emission from the 5 p56 p excited state to the 5 p56 s intermediate electronic state was used to detect the two-photon transition. Hyperfine constants and isotope shift parameters were evaluated and compared with previously reported values. In addition, the detected photon count rate was estimated from the observed intensities.

  3. Unconventional phases in quantum spin and pseudospin systems in two dimensional and three dimensional lattices

    Science.gov (United States)

    Xu, Cenke

    Several examples of quantum spin systems and pseudo spin systems have been studied, and unconventional states of matters and phase transitions have been realized in all these systems under consideration. In the p +/- ip superconductor Josephson lattice and the p--band cold atomic system trapped in optical lattices, novel phases which behave similarly to 1+1 dimensional systems are realized, despite the fact that the real physical systems are in two or three dimensional spaces. For instance, by employing a spin-wave analysis together with a new duality transformation, we establish the existence and stability of a novel gapless "critical phase", which we refer to as a "bond algebraic liquid". This novel critical phase is analogous to the 1+1 dimensional algebraic boson liquid phase. The reason for the novel physics is that there is a quasilocal gauge symmetry in the effective low energy Hamiltonian. In a spin-1 system on the kagome lattice, and a hard-core boson system on the honeycomb lattice, the low energy physics is controlled by two components of compact U(1) gauge symmetries that emerge at low energy. Making use of the confinement nature of the 2+1 dimensional compact gauge theories and the powerful duality between gauge theories and height field theories, the crystalline phase diagrams are studied for both systems, and the transitions to other phases are also considered. These phase diagrams might be accessible in strongly correlated materials, or atomic systems in optical lattices. A novel quantum ground state of matter is realized in a bosonic model on three dimensional fcc lattice with emergent low energy excitations. The novel phase obtained is a stable gapless boson liquid phase, with algebraic boson density correlations. The stability of this phase is protected against the instanton effect and superfluidity by self-duality and large gauge symmetries on both sides of the duality. The gapless collective excitations of this phase closely resemble the

  4. Study on flow instabilities in two-phase mixtures

    International Nuclear Information System (INIS)

    Ishii, M.

    1976-03-01

    Various mechanisms that can induce flow instabilities in two-phase flow systems are reviewed and their relative importance discussed. In view of their practical importance, the density-wave instabilities have been analyzed in detail based on the one-dimensional two-phase flow formulation. The dynamic response of the system to the inlet flow perturbations has been derived from the model; thus the characteristic equation that predicts the onset of instabilities has been obtained. The effects of various system parameters, such as the heat flux, subcooling, pressure, inlet velocity, inlet orificing, and exit orificing on the stability boundary have been analyzed. In addition to numerical solutions, some simple stability criteria under particular conditions have been obtained. Both results have been compared with various experimental data, and a satisfactory agreement has been demonstrated

  5. Two-phase flow stability structure in a natural circulation system

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, Zhiwei [Nuclear Engineering Laboratory Zurich (Switzerland)

    1995-09-01

    The present study reports a numerical analysis of two-phase flow stability structures in a natural circulation system with two parallel, heated channels. The numerical model is derived, based on the Galerkin moving nodal method. This analysis is related to some design options applicable to integral heating reactors with a slightly-boiling operation mode, and is also of general interest to similar facilities. The options include: (1) Symmetric heating and throttling; (2) Asymmetric heating and symmetric throttling; (3) Asymmetric heating and throttling. The oscillation modes for these variants are discussed. Comparisons with the data from the INET two-phase flow stability experiment have qualitatively validated the present analysis.

  6. Comparative performance and microbial community of single-phase and two-phase anaerobic systems co-digesting cassava pulp and pig manure

    DEFF Research Database (Denmark)

    Panichnumsin, P.; Ahring, B.K.; Nopharatana, A.

    2010-01-01

    In this study, we illustrated the performance and microbial community of single- and two-phase systems anaerobically co-digesting cassava pulp and pig manure. The results showed that the volatile solid reduction and biogas productivity of two-phase CSTR were 66 ± 4% and 2000 ± 210 ml l-1 d-1, while...... those of singlephase CSTR were 59 ± 1% and 1670 ± 60 ml l-1 d-1, respectively. Codigestion in two-phase CSTR gave higher 12% solid degradation and 25% methane production than single-phase CSTR. Phylogenetic analysis of 16S rDNA clone library revealed that the Bacteroidetes were the most abundant group......, followed by the Clostridia in singlephase CSTR. In hydrolysis/acidification reactor of two-phase system, the bacteria within the phylum Firmicutes, especially Clostridium, Eubacteriaceae and Lactobacillus were the dominant phylogenetic groups. Among the Archaea, Methanosaeta sp. was the exclusive...

  7. Validation of Friction Models in MARS-MultiD Module with Two-Phase Cross Flow Experiment

    International Nuclear Information System (INIS)

    Choi, Chi-Jin; Yang, Jin-Hwa; Cho, Hyoung-Kyu; Park, Goon-Cher; Euh, Dong-Jin

    2015-01-01

    In the downcomer of Advanced Power Reactor 1400 (APR1400) which has direct vessel injection (DVI) lines as an emergency core cooling system, multidimensional two-phase flow may occur due to the Loss-of-Coolant-Accident (LOCA). The accurate prediction about that is high relevance to evaluation of the integrity of the reactor core. For this reason, Yang performed an experiment that was to investigate the two-dimensional film flow which simulated the two-phase cross flow in the upper downcomer, and obtained the local liquid film velocity and thickness data. From these data, it could be possible to validate the multidimensional modules of system analysis codes. In this study, MARS-MultiD was used to simulate the Yang's experiment, and obtained the local variables. Then, the friction models used in MARS-MultiD were validated by comparing the two-phase flow experimental results with the calculated local variables. In this study, the two-phase cross flow experiment was modeled by the MARS-MultiD. Compared with the experimental results, the calculated results by the code properly presented mass conservation which could be known from the relation between the liquid film velocity and thickness at the same flow rate. The magnitude and direction of the liquid film, however, did not follow well with experimental results. According to the results of Case-2, wall friction should be increased, and interfacial friction should be decreased in MARS-MultiD. These results show that it is needed to modify the friction models in the MARS-MultiD to simulate the two-phase cross flow

  8. Preliminary Two-Phase Terry Turbine Nozzle Models for RCIC Off-Design Operation Conditions

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, Haihua [Idaho National Lab. (INL), Idaho Falls, ID (United States); O' Brien, James [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2017-06-12

    This report presents the effort to extend the single-phase analytical Terry turbine model to cover two-phase off-design conditions. The work includes: (1) adding well-established two-phase choking models – the Isentropic Homogenous Equilibrium Model (IHEM) and Moody’s model, and (2) theoretical development and implementation of a two-phase nozzle expansion model. The two choking models provide bounding cases for the two-phase choking mass flow rate. The new two-phase Terry turbine model uses the choking models to calculate the mass flow rate, the critical pressure at the nozzle throat, and steam quality. In the divergent stage, we only consider the vapor phase with a similar model for the single-phase case by assuming that the liquid phase would slip along the wall with a much slower speed and will not contribute the impulse on the rotor. We also modify the stagnation conditions according to two-phase choking conditions at the throat and the cross-section areas for steam flow at the nozzle throat and at the nozzle exit. The new two-phase Terry turbine model was benchmarked with the same steam nozzle test as for the single-phase model. Better agreement with the experimental data is observed than from the single-phase model. We also repeated the Terry turbine nozzle benchmark work against the Sandia CFD simulation results with the two-phase model for the pure steam inlet nozzle case. The RCIC start-up tests were simulated and compared with the single-phase model. Similar results are obtained. Finally, we designed a new RCIC system test case to simulate the self-regulated Terry turbine behavior observed in Fukushima accidents. In this test, a period inlet condition for the steam quality varying from 1 to 0 is applied. For the high quality inlet period, the RCIC system behaves just like the normal operation condition with a high pump injection flow rate and a nominal steam release rate through the turbine, with the net addition of water to the primary system; for

  9. The phase system Fe-Ir-S at 1100, 1000 and 800 degree C

    DEFF Research Database (Denmark)

    Makovicky, Emil; Karup-Møller, Sven

    1999-01-01

    Phase relations in the dry condensed Fe-Ir-S system were determined at 1100, 1000 and 800 degrees C. Orientational runs were performed at 500 degrees C. Between 1100 and 800 degrees C, the system comprises five sulphides and an uninterrupted field of gamma(Fe, Ir). Fe1-xS dissolves 5.8 at.% Ir...... at 1100 degrees C, 3.4 at.% Ir at 1000 degrees C and 1.0 at.% Ir at 800 degrees C. The solubility of Fe in Ir2S3, IrS2 and IrSsimilar to 3 increases with decreasing temperature, reaching 2.5 at.% in the latter two sulphides at 800 degrees C. Thiospinel 'FeIr2S4' is nonstoichiometric, from Fe22.3Ir19.8S58...

  10. AsS melt under pressure: one substance, three liquids.

    Science.gov (United States)

    Brazhkin, V V; Katayama, Y; Kondrin, M V; Hattori, T; Lyapin, A G; Saitoh, H

    2008-04-11

    An in situ high-temperature--high-pressure study of liquid chalcogenide AsS by x-ray diffraction, resistivity measurements, and quenching from melt is presented. The obtained data provide direct evidence for the existence in the melt under compression of two transformations: one is from a moderate-viscosity molecular liquid to a high-viscosity nonmetallic polymerized liquid at P approximately 1.6-2.2 GPa; the other is from the latter to a low-viscosity metallic liquid at P approximately 4.6-4.8 GPa. Upon rapid cooling, molecular and metallic liquids crystallize to normal and high-pressure phases, respectively, while a polymerized liquid is easily quenched to a new AsS glass. General aspects of multiple phase transitions in liquid AsS, including relations to the phase diagram of the respective crystalline, are discussed.

  11. Two-group interfacial area concentration correlations of two-phase flows in large diameter pipes

    International Nuclear Information System (INIS)

    Shen, Xiuzhong; Hibiki, Takashi

    2015-01-01

    The reliable empirical correlations and models are one of the important ways to predict the interfacial area concentration (IAC) in two-phase flows. However, up to now, no correlation or model is available for the prediction of the IAC in the two-phase flows in large diameter pipes. This study collected an IAC experimental database of two-phase flows taken under various flow conditions in large diameter pipes and presented a systematic way to predict the IAC for two-phase flows from bubbly, cap-bubbly to churn flow in large diameter pipes by categorizing bubbles into two groups (group-1: spherical and distorted bubble, group-2: cap bubble). Correlations were developed to predict the group-1 void fraction from the void fraction of all bubble. The IAC contribution from group-1 bubbles was modeled by using the dominant parameters of group-1 bubble void fraction and Reynolds number based on the parameter-dependent analysis of Hibiki and Ishii (2001, 2002) using one-dimensional bubble number density and interfacial area transport equations. A new drift velocity correlation for two-phase flow with large cap bubbles in large diameter pipes was derived in this study. By comparing the newly-derived drift velocity correlation with the existing drift velocity correlation of Kataoka and Ishii (1987) for large diameter pipes and using the characteristics of the representative bubbles among the group 2 bubbles, we developed the model of IAC and bubble size for group 2 cap bubbles. The developed models for estimating the IAC are compared with the entire collected database. A reasonable agreement was obtained with average relative errors of ±28.1%, ±54.4% and ±29.6% for group 1, group 2 and all bubbles respectively. (author)

  12. Evaluation of a solid phase R.I.A. technique and solid phase E.L.I.S.A. technique for the demonstration of hepatitis B surface antigen

    International Nuclear Information System (INIS)

    Vranckx, R.; Cole, J.; Peetermans, M.

    1977-01-01

    We compared the sensitivity of a solidphase radio-immunoassay (R.I.A.), a solid-phase enzyme-immunoassay (E.L.I.S.A.) and a hemagglutination test (R.P.H.A.) for the detection of the HBs Ag in two ways: 1) by screening a panel of 300 sera (97 positives and 203 negatives) 2) by titrating serial dilutions of 10 positive sera. Ninety seven sera were positive by R.I.A., 95% were detected by E.L.I.S.A. and 81% were detected by R.P.H.A. In the serial dilutions the average end points of the titration were for R.I.A. 0.005 ng/ml, for E.L.I.S.A. 0,01 ng/ml and for R.P.H.A. 0.04 ng/ml. It can be concluded that the sensitivity of the E.L.I.S.A. test is intermediate between the sensitivity of the R.I.A. and the sensitivity of the R.P.H.A. The E.L.I.S.A. and the R.P.H.A. tests seam to be a little more sensitive for the detection of subtype ay than the detection of subtype ad. (orig.) [de

  13. A new method of testing pile using dynamic P-S-curve made by amplitude of wave train

    Science.gov (United States)

    Hu, Yi-Li; Xu, Jun; Duan, Yong-Kong; Xu, Zhao-Yong; Yang, Run-Hai; Zhao, Jin-Ming

    2004-11-01

    A new method of detecting the vertical bearing capacity for single-pile with high strain is discussed in this paper. A heavy hammer or a small type of rocket is used to strike the pile top and the detectors are used to record vibration graphs. An expression of higher degree of strain (deformation force) is introduced. It is testified theoretically that the displacement, velocity and acceleration cannot be obtained by simple integral acceleration and differential velocity when long displacement and high strain exist, namely when the pile phase generates a whole slip relative to the soil body. That is to say that there are non-linear relations between them. It is educed accordingly that the force P and displacement S are calculated from the amplitude of wave train and (dynamic) P-S curve is drew so as to determine the yield points. Further, a method of determining the vertical bearing capacity for single-pile is discussed. A static load test is utilized to check the result of dynamic test and determine the correlative constants of dynamic-static P( Q)- S curve.

  14. Measurement of phase interaction in dispersed gas-particle two-phase flow by phase-doppler anemometry

    Directory of Open Access Journals (Sweden)

    Mergheni Ali Mohamed

    2008-01-01

    Full Text Available For simultaneous measurement of size and velocity distributions of continuous and dispersed phases in a two-phase flow a technique phase-Doppler anemometry was used. Spherical glass particles with a particle diameter range from 102 up to 212 µm were used. In this two-phase flow an experimental results are presented which indicate a significant influence of the solid particles on the flow characteristics. The height of influence of these effects depends on the local position in the jet. Near the nozzle exit high gas velocity gradients exist and therefore high turbulence production in the shear layer of the jet is observed. Here the turbulence intensity in the two-phase jet is decreased compared to the single-phase jet. In the developed zone the velocity gradient in the shear layer is lower and the turbulence intensity reduction is higher. .

  15. Construction of the two-phase critical flow test facility

    International Nuclear Information System (INIS)

    Chung, C. H.; Chang, S. K.; Park, H. S.; Min, K. H.; Choi, N. H.; Kim, C. H.; Lee, S. H.; Kim, H. C.; Chang, M. H.

    2002-03-01

    The two-phase critical test loop facility has been constructed in the KAERI engineering laboratory for the simulation of small break loss of coolant accident entrained with non-condensible gas of SMART. The test facility can operate at 12 MPa of pressure and 0 to 60 C of sub-cooling with 0.5 kg/s of non- condensible gas injection into break flow, and simulate up to 20 mm of pipe break. Main components of the test facility were arranged such that the pressure vessel containing coolant, a test section simulating break and a suppression tank inter-connected with pipings were installed vertically. As quick opening valve opens, high pressure/temperature coolant flows through the test section forming critical two-phase flow into the suppression tank. The pressure vessel was connected to two high pressure N2 gas tanks through a control valve to control pressure in the pressure vessel. Another N2 gas tank was also connected to the test section for the non-condensible gas injection. The test facility operation was performed on computers supported with PLC systems installed in the control room, and test data such as temperature, break flow rate, pressure drop across test section, gas injection flow rate were all together gathered in the data acquisition system for further data analysis. This test facility was classified as a safety related high pressure gas facility in law. Thus the loop design documentation was reviewed, and inspected during construction of the test loop by the regulatory body. And the regulatory body issued permission for the operation of the test facility

  16. Thermo-Fluid Dynamics of Two-Phase Flow

    CERN Document Server

    Ishii, Mamrou

    2011-01-01

    "Thermo-fluid Dynamics of Two-Phase Flow, Second Edition" is focused on the fundamental physics of two-phase flow. The authors present the detailed theoretical foundation of multi-phase flow thermo-fluid dynamics as they apply to: Nuclear reactor transient and accident analysis; Energy systems; Power generation systems; Chemical reactors and process systems; Space propulsion; Transport processes. This edition features updates on two-phase flow formulation and constitutive equations and CFD simulation codes such as FLUENT and CFX, new coverage of the lift force model, which is of part

  17. Overview of $C\\!P$V parameter $\\phi_{s}$ determination

    CERN Document Server

    Batozskaya, Varvara

    2018-01-01

    The one of main goals of the LHCb experiment is the measurement of the mixing-induced $C\\!P$-violating phase $\\phi_{s}$ in the $B^{0}_{s}-\\bar{B}^{0}_{s}$ system. It has been measured exploiting the Run~I data set, using several decay channels. The most recent results obtained analyzing $B^{0}_{s}\\to J/\\psi K^{+}K^{-}$ candidates in the $K^{+}K^{-}$ mass region above the $\\phi(1020)$ resonance are presented. The measurements using the same final state with the $m(K^{+}K^{-})$ at the $\\phi(1020)$ and $B^{0}_{s}\\to J/\\psi \\pi^{+}\\pi^{-}$, as well as using the $B^{0}_{s}\\to \\psi(2S)\\phi$ decay are discussed.

  18. T- P Phase Diagram of Nitrogen at High Pressures

    Science.gov (United States)

    Algul, G.; Enginer, Y.; Yurtseven, H.

    2018-05-01

    By employing a mean field model, calculation of the T- P phase diagram of molecular nitrogen is performed at high pressures up to 200 GPa. Experimental data from the literature are used to fit a quadratic function in T and P, describing the phase line equations which have been derived using the mean field model studied here for N 2, and the fitted parameters are determined. Our model study gives that the observed T- P phase diagram can be described satisfactorily for the first-order transitions between the phases at low as well as high pressures in nitrogen. Some thermodynamic quantities can also be predicted as functions of temperature and pressure from the mean field model studied here and they can be compared with the experimental data.

  19. Self-broadening and shifting of the Li(2s-2p) and K(4s-4p) line cores

    International Nuclear Information System (INIS)

    Reggami, L.; Bouledroua, M.; Allouche, A.R.; Aubert-Frecon, M.

    2009-01-01

    The aim of this work is to determine quantum mechanically the width Γ and the shift Δ of the lithium Li(2p→2s) and potassium K(4p→4s) resonance lines when these atoms are evolving in their parent gases. The interaction potentials along which the atoms Li(2p)+Li(2s) and K(4p)+K(4s) approach each other are constructed from reliable data. The radial wave equation is then solved numerically by using these potentials to compute the elastic phase shifts. By adopting the simplified Baranger model for the pressure broadening, which assumes the impact approximation, the cross sections effective in linewidth and lineshift are analyzed. The analysis leads in particular to the determination of the width and shift rates and the computations show that these rates have constant values and, mainly, do not depend on temperature. An approximate method is further applied to the calculations of the cross sections. The results reveal the influence of the long-range -C 3 /R 3 interactions and confirm the universality of the obtained formulas of Γ and Δ

  20. Characterizing dynamic hysteresis and fractal statistics of chaotic two-phase flow and application to fuel cells

    International Nuclear Information System (INIS)

    Burkholder, Michael B.; Litster, Shawn

    2016-01-01

    In this study, we analyze the stability of two-phase flow regimes and their transitions using chaotic and fractal statistics, and we report new measurements of dynamic two-phase pressure drop hysteresis that is related to flow regime stability and channel water content. Two-phase flow dynamics are relevant to a variety of real-world systems, and quantifying transient two-phase flow phenomena is important for efficient design. We recorded two-phase (air and water) pressure drops and flow images in a microchannel under both steady and transient conditions. Using Lyapunov exponents and Hurst exponents to characterize the steady-state pressure fluctuations, we develop a new, measurable regime identification criteria based on the dynamic stability of the two-phase pressure signal. We also applied a new experimental technique by continuously cycling the air flow rate to study dynamic hysteresis in two-phase pressure drops, which is separate from steady-state hysteresis and can be used to understand two-phase flow development time scales. Using recorded images of the two-phase flow, we show that the capacitive dynamic hysteresis is related to channel water content and flow regime stability. The mixed-wettability microchannel and in-channel water introduction used in this study simulate a polymer electrolyte fuel cell cathode air flow channel.

  1. Characterizing dynamic hysteresis and fractal statistics of chaotic two-phase flow and application to fuel cells

    Energy Technology Data Exchange (ETDEWEB)

    Burkholder, Michael B.; Litster, Shawn, E-mail: litster@andrew.cmu.edu [Department of Mechanical Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213 (United States)

    2016-05-15

    In this study, we analyze the stability of two-phase flow regimes and their transitions using chaotic and fractal statistics, and we report new measurements of dynamic two-phase pressure drop hysteresis that is related to flow regime stability and channel water content. Two-phase flow dynamics are relevant to a variety of real-world systems, and quantifying transient two-phase flow phenomena is important for efficient design. We recorded two-phase (air and water) pressure drops and flow images in a microchannel under both steady and transient conditions. Using Lyapunov exponents and Hurst exponents to characterize the steady-state pressure fluctuations, we develop a new, measurable regime identification criteria based on the dynamic stability of the two-phase pressure signal. We also applied a new experimental technique by continuously cycling the air flow rate to study dynamic hysteresis in two-phase pressure drops, which is separate from steady-state hysteresis and can be used to understand two-phase flow development time scales. Using recorded images of the two-phase flow, we show that the capacitive dynamic hysteresis is related to channel water content and flow regime stability. The mixed-wettability microchannel and in-channel water introduction used in this study simulate a polymer electrolyte fuel cell cathode air flow channel.

  2. What Do s- and p-Wave Neutron Average Radiative Widths Reveal

    Energy Technology Data Exchange (ETDEWEB)

    Mughabghab, S.F.

    2010-04-30

    A first observation of two resonance-like structures at mass numbers 92 and 112 in the average capture widths of the p-wave neutron resonances relative to the s-wave component is interpreted in terms of a spin-orbit splitting of the 3p single-particle state into P{sub 3/2} and P{sub 1/2} components at the neutron separation energy. A third structure at about A = 124, which is not correlated with the 3p-wave neutron strength function, is possibly due to the Pygmy Dipole Resonance. Five significant results emerge from this investigation: (i) The strength of the spin-orbit potential of the optical-model is determined as 5.7 {+-} 0.5 MeV, (ii) Non-statistical effects dominate the p-wave neutron-capture in the mass region A = 85 - 130, (iii) The background magnitude of the p-wave average capture-width relative to that of the s-wave is determined as 0.50 {+-} 0.05, which is accounted for quantitatively in tenns of the generalized Fermi liquid model of Mughabghab and Dunford, (iv) The p-wave resonances arc partially decoupled from the giant-dipole resonance (GDR), and (v) Gamma-ray transitions, enhanced over the predictions of the GDR, are observed in the {sup 90}Zr - {sup 98}Mo and Sn-Ba regions.

  3. Identification of two distinct allergenic sites on ryegrass-pollen allergen, Lol p IV.

    Science.gov (United States)

    Jaggi, K S; Ekramoddoullah, A K; Kisil, F T; Dzuba-Fischer, J M; Rector, E S; Sehon, A H

    1989-04-01

    Lol p IV is an important allergen of ryegrass pollen. For the immunochemical identification of antigenic and/or allergenic site(s), murine monoclonal antibodies (MAbs) were prepared against Lol p IV. The hybridoma cell-culture supernatants were screened for anti-Lol p IV antibodies by a combination of ELISA and Western immunoblot analyses. The MAbs were finally purified from ascites on a Mono Q ion-exchange column. In a competitive radioimmunoassay with Lol p IV as the solid phase and 125I-labeled MAbs, it was established that MAbs 90, 91, 92, 93, and 94, although they differed in their relative affinities, recognized in common with one another an epitope designated as antigenic site A, whereas MAb 12 recognized a different epitope referred to as site B. Sites A and B were also demonstrated to constitute allergenic determinants of Lol p IV. Differences in the repertoire of specificities of the human IgE antibodies directed to Lol p IV were also demonstrated. Interestingly, it was found that sera from both allergic as well as from nonatopic individuals had IgG antibodies to sites A and/or B.

  4. Pressure drop of magnetohydrodynamic two-phase annular flow in rectangular channel

    International Nuclear Information System (INIS)

    Kumamaru, Hiroshige; Fujiwara, Yoshiki; Ogita, Kenji

    1999-01-01

    Numerical calculations have been performed on magnetohydrodynamic (MHD) two-phase annular flow in a rectangular channel with a small aspect ratio, i.e.a small ratio of the channel side perpendicular to the applied magnetic field and the side parallel to the field. Results of the present calculation agree nearly with Inoue et al.'s experimental results in the region of large liquid Reynolds numbers and large Hartmann numbers. Calculation results also show that the pressure drop ratio, i.e. the ratio of pressure drop of two-phase flow to that of single-phase flow under the same liquid flow rate and applied magnetic field, becomes lower than ∼0.02 for conditions of a fusion reactor plant. (author)

  5. S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component.

    Science.gov (United States)

    Zheng, Lei; Roeder, Robert G; Luo, Yan

    2003-07-25

    We have isolated and functionally characterized a multicomponent Oct-1 coactivator, OCA-S which is essential for S phase-dependent histone H2B transcription. The p38 component of OCA-S binds directly to Oct-1, exhibits potent transactivation potential, is selectively recruited to the H2B promoter in S phase, and is essential for S phase-specific H2B transcription in vivo and in vitro. Surprisingly, p38 represents a nuclear form of glyceraldehyde-3-phosphate dehydrogenase, and binding to Oct-1, as well as OCA-S function, is stimulated by NAD(+) but inhibited by NADH. OCA-S also interacts with NPAT, a cyclin E/cdk2 substrate that is broadly involved in histone gene transcription. These studies thus link the H2B transcriptional machinery to cell cycle regulators, and possibly to cellular metabolic state (redox status), and set the stage for studies of the underlying mechanisms and the basis for coordinated histone gene expression and coupling to DNA replication.

  6. Evaluation of two-phase thermophilic anaerobic methane fermentation for the treatment of garbage

    International Nuclear Information System (INIS)

    Park, Y.J.; Hong, F.; Japan Science and Technology Agency, Tokyo; Tsuno, H.; Hidaka, T.; Cheon, J.H.; Japan Science and Technology Agency, Tokyo

    2004-01-01

    Municipal solid wastes (MSW) in Japan are generally incinerated. However, in recent years, garbage has been recognized as a renewable energy source. This has resulted in an increase in the use of biological processes, such as anaerobic digestion, to treat organic waste such as sewage sludge and garbage. The two phases of anaerobic digestion are the acidogenic phase and the methane producing phase. Both differ significantly in their nutritional and physiological requirements. This study evaluated the effectiveness of treating garbage with the two-phase thermophilic methane fermentation system (TPS). The performance of the acid fermentation phase in TPS was examined with particular reference to operational parameters such as pH, hydraulic retention time and organic loading rate on volatile fatty acid fermentation. It was shown that TPS was more efficient than the single-phase thermophilic methane fermentation system (SPS). Acidification control in the first stage resulted in better stability of methane fermentation in the second stage. VFA formation was optimized at a pH of 6. The recovery ratios of VFAs and methane were achieved in the range of 42 to 44 per cent and 88 to 91 per cent of garbage by high organic loading rate respectively. 12 refs., 6 tabs., 4 figs

  7. Predictions for the Dirac C P -violating phase from sum rules

    Science.gov (United States)

    Delgadillo, Luis A.; Everett, Lisa L.; Ramos, Raymundo; Stuart, Alexander J.

    2018-05-01

    We explore the implications of recent results relating the Dirac C P -violating phase to predicted and measured leptonic mixing angles within a standard set of theoretical scenarios in which charged lepton corrections are responsible for generating a nonzero value of the reactor mixing angle. We employ a full set of leptonic sum rules as required by the unitarity of the lepton mixing matrix, which can be reduced to predictions for the observable mixing angles and the Dirac C P -violating phase in terms of model parameters. These sum rules are investigated within a given set of theoretical scenarios for the neutrino sector diagonalization matrix for several known classes of charged lepton corrections. The results provide explicit maps of the allowed model parameter space within each given scenario and assumed form of charged lepton perturbations.

  8. Film thickness in gas-liquid two-phase flow, (2)

    International Nuclear Information System (INIS)

    Sekoguchi, Kotohiko; Fukano, Toru; Kawakami, Yasushi; Shimizu, Hideo.

    1977-01-01

    The effect of four rectangular obstacles inserted into a circular tube has been studied in gas-liquid two-phase flow. The obstacles are set on the inner wall of the tube, and the ratio of the opening is 0.6. The water film flows partially through the obstacles. The minimum thickness of water film was measured in relation to flow speed. The serious effect of the obstacles was seen against the formation of water film, and drainage under the obstacles and backward flow play important roles. Since water film can flow partially through the obstacles, the film in case of the rectangular obstacles in thicker than that in case of an orifice when the gas flow speed was slower than 5 m/s. However, when the gas flow speed is over 5 m/s, the film thickness was thinner. The minimum film thickness of downstream of the obstacles was almost same as that in case of no obstacle. The minimum film thickness of up stream depends on the location of measurement due to the effect of drainage. (Kato, T.)

  9. Phase study in Sr-Th-P-O system: Structural and thermal investigations of quaternary compounds

    International Nuclear Information System (INIS)

    Keskar, Meera; Phatak, Rohan; Sali, S.K.; Krishnan, K.; Dahale, N.D.; Kulkarni, N.K.; Kannan, S.

    2011-01-01

    The sub-solidus phase relations in Sr-Th-P-O quaternary system were determined at 1223 K in air. To confirm the formation and stability of reported phases, ternary and quaternary compounds in Sr-Th-O, Sr-P-O, Th-P-O and Sr-Th-P-O systems were synthesized by solid state reactions of SrCO 3 , ThO 2 and NH 4 H 2 PO 4 in desired molar proportions at 1223 K. A pseudo-ternary phase diagram of SrO-ThO 2 -P 2 O 5 system was drawn on the basis of the phase analysis of various phase mixtures and phase fields were established by powder X-ray diffraction. In the phase diagram, three quaternary compounds SrTh(PO 4 ) 2 , SrTh 4 (PO 4 ) 6 and Sr 7 Th(PO 4 ) 6 were identified. When heated in air at 1673 K, these compounds decompose to ThO 2 . Structures of SrTh(PO 4 ) 2 , SrTh 4 (PO 4 ) 6 and Sr 7 Th(PO 4 ) 6 were derived from X-ray powder data using the Rietveld refinement method. Thermal expansion behaviors of SrTh(PO 4 ) 2 , SrTh 4 (PO 4 ) 6 and Sr 7 Th(PO 4 ) 6 were investigated using high-temperature X-ray diffraction in the temperature range of 298-1273 K.

  10. G.P.S. Occhialini 1907-93

    International Nuclear Information System (INIS)

    Peyrou, C.

    1994-01-01

    G.P.S. Occhialini, a legendary figure for all who remember the very beginnings of cosmic ray particle physics, died on 30 December. Born on 5 December 1907 in Rossombrone, near Urbino, he studied in Florence. Here he met Bruno Rossi, whom, although only two years his senior, he always regarded as a master. In 1932 Occhialini went to Cambridge where he worked with P.M.S. Blackett. They invented and perfected the counter-triggered Wilson chamber technique, recording cascade showers which confirmed the existence of the positron, discovered slightly earlier by Anderson, and demonstrating its symmetry with the electron

  11. Numerical modeling of two-phase transonic flow

    Czech Academy of Sciences Publication Activity Database

    Halama, Jan; Benkhaldoun, F.; Fořt, Jaroslav

    2010-01-01

    Roč. 80, č. 88 (2010), s. 1624-1635 ISSN 0378-4754 Grant - others:GA ČR(CZ) GA201/08/0012 Program:GA Institutional research plan: CEZ:AV0Z20760514 Keywords : two - phase flow * condensation * fractional step method Subject RIV: BK - Fluid Dynamics Impact factor: 0.812, year: 2010 http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6V0T-4VNK68X-2-R&_cdi=5655&_user=640952&_pii=S0378475409000421&_origin=search&_coverDate=04%2F30%2F2010&_sk=999199991&view=c&wchp=dGLzVlb-zSkWb&md5=5ba607428fac339a3e5f67035d3996d0&ie=/sdarticle.pdf

  12. Fermi's ansatz and Bohm's quantum potential

    Energy Technology Data Exchange (ETDEWEB)

    Dennis, Glen, E-mail: gdennis502@gmail.com [TPRU, Birkbeck College, University of London, London, WC1E 7HX (United Kingdom); Gosson, Maurice A. de, E-mail: maurice.de.gosson@univie.ac.at [University of Vienna, Faculty of Mathematics, NuHAG, Oskar-Morgenstern-Platz 1, 1090 Vienna (Austria); Hiley, Basil J., E-mail: b.hiley@bbk.ac.uk [TPRU, Birkbeck College, University of London, London, WC1E 7HX (United Kingdom)

    2014-06-27

    In this paper we address the following simple question: Given a wavefunction ψ(x,t) in a one-dimensional configuration space, is it possible to give a unique two-dimensional representation ρ(x,p,t) in a position-momentum phase plane? If so, can we find the general condition that makes this possible? We will show that this is indeed possible by using an idea introduced originally by Fermi provided the boundary of the phase space area is a closed curve satisfying a certain exact quantum condition. - Highlights: • We review “Fermi's trick” which allows one to view an arbitrary wavefunction as a stationary state for some Hamiltonian operator H{sub F}. This Hamiltonian contains the quantum potential. • We study the relation between Fermi's trick and an exact quantization condition which reduces to the familiar EBK condition in the limit ħ→0. • This allows us to relate the Fermi set H{sub F}(x,p)=0 to the notion of quantum blob introduced by one of us in previous work. Quantum blobs are phase space regions corresponding to minimum uncertainty. • We discuss our results from the point of view of the quantum theory of motion.

  13. Phase relationships of the system Fe-Ni-S and structure of the high-pressure phase of (Fe1-xNix)3S2

    Science.gov (United States)

    Urakawa, Satoru; Kamuro, Ryota; Suzuki, Akio; Kikegawa, Takumi

    2018-04-01

    The phase relationships of the Fe-Ni-S system at 15 GPa were studied by high pressure quench experiments. The stability fields of (Fe,Ni)3S and (Fe,Ni)3S2 and the melting relationships of the Fe-Ni-S system were determined as a function of Ni content. The (Fe,Ni)3S solid solution is stable in the composition of Ni/(Fe + Ni) > 0.7 and melts incongruently into an Fe-Ni alloy + liquid. The (Fe,Ni)3S2 makes a complete solid solution and melts incongruently into (Fe,Ni)S + liquid, whose structure was determined to show Cmcm-orthorhombic symmetry by in situ synchrotron X-ray diffraction experiments. The eutectic contains about 30 at.% of S, and its temperature decreases with increasing Ni content with a rate of ∼5 K/at.% from 1175 K. The density of the Fe-FeS eutectic composition (Fe70S30) liquid is evaluated to be 6.93 ± 0.08 g/cm3 at 15 GPa and 1200 K based on the Clausius-Clapeyron relations and densities of subsolidus phases. The Fe-Ni-S liquids are a primary sulfur-bearing phase in the deep mantle with a reducing condition (250-660 km depth), and they would play a significant role in the carbon cycle as a carbon host as well as in the generation of diamond.

  14. Measurement of phase interaction in dispersed gas-particle two-phase flow by phase-doppler anemometry

    OpenAIRE

    Mergheni Ali Mohamed; Ben Ticha Hmaied; Sautet Jen-Charles; Godard Gille; Ben Nasrallah Sassi

    2008-01-01

    For simultaneous measurement of size and velocity distributions of continuous and dispersed phases in a two-phase flow a technique phase-Doppler anemometry was used. Spherical glass particles with a particle diameter range from 102 up to 212 µm were used. In this two-phase flow an experimental results are presented which indicate a significant influence of the solid particles on the flow characteristics. The height of influence of these effects depends on the local position in the jet. Near t...

  15. Influence of two-phase anaerobic digestion on fate of selected antibiotic resistance genes and class I integrons in municipal wastewater sludge.

    Science.gov (United States)

    Wu, Ying; Cui, Erping; Zuo, Yiru; Cheng, Weixiao; Rensing, Christopher; Chen, Hong

    2016-07-01

    The response of representative antibiotic resistance genes (ARGs) to lab-scale two-phase (acidogenic/methanogenic phase) anaerobic digestion processes under thermophilic and mesophilic conditions was explored. The associated microbial communities and bacterial pathogens were characterized by 16S rRNA gene sequencing. A two-phase thermophilic digestion reduced the presence of tetA, tetG, tetX, sul1, ermB, dfrA1, dfrA12 and intI1 exhibiting 0.1-0.72 log unit removal; in contrast, tetO, tetW, sul3, ermF and blaTEM even increased relative to the feed, and sul2 showed no significant decrease. The acidogenic phase of thermophilic digestion was primarily responsible for reducing the quantity of these genes, while the subsequent methanogenic phase caused a rebound in their quantity. In contrast, a two-phase mesophilic digestion process did not result in reducing the quantity of all ARGs and intI1 except for ermB and blaTEM. ARGs patterns were correlated with Proteobacteria and Actinobacteria during the two-phase anaerobic digestion. Copyright © 2016 Elsevier Ltd. All rights reserved.

  16. Extraction of UO22+ by two highly sterically hindered (X1) (X2) PO(OH) extractants from an aqueous chloride phase

    International Nuclear Information System (INIS)

    Mason, G.W.; Lewey, S.M.; Gilles, D.M.; Peppard, D.F.

    1978-01-01

    The comparative extraction behaviour of tracer-level UO 2 2+ into benzene solutions of two highly sterically hindered extractants, di(2,6-di-iso-propylphenyl) phosphoric acid, HD(2,6-i-PPHI)P and di-tertiary-butyl phosphinic acid, H[Dt-BP], vs an aqueous 1.0 F (NaCl + HCl) phase was studied. The extraction of UO 2 2+ in both systems is directly second-power dependent upon extractant concentration and inversely second-power dependent upon hydrogen ion concentration, the stoichiometry of extraction being UOsub(2A) 2+ + 2(HY)sub(2O) = UO 2 (HY 2 )sub(2O) + 2Hsub(A) + . The expression for the distribution ratio, K is K = Ksub(s)F 2 /[H + ] 2 the general expression for the extraction of any metallic species being K - Ksub(s)Fsup(a)/[H + ]sup(b) where Ksub(s) is a constant characteristic of the system, F the concentration in formality units of extractant in the organic phase, [H + ] the concentration of hydrogen ion in the aqueous phase, and a and b the respective extractant and hydrogen-ion dependencies. Both extractants have a high degree of steric hindrance. The HD(2,6-i-PPHI)P is the more highly acidic, the pKsub(A) value, in 75% ethanol, being 3.2. The pKsub(A), previously reported, for H[Dt-BP] is 6.26. The Ksub(s) for UO 2 2+ in the system HY in benzene diluent vs an aqueous 1.0 F (NaCl + HCl) phase is 2 x 10 4 for H[Dt-BP] and 3 x 10 -1 for HD(2,6-i-PPHI)P; the ratio of the Ksub(s) values nearly 7 x 10 3 , favours the less acidic extractant. For comparative purposes, the Ksub(s) values for UO 2 2+ and for Am 3+ and Eu 3+ in other (X 1 )(X 2 )PO(OH), in benzene diluent, vs 1.0 F (NaCl + HCl) systems are presented. The variations are discussed in terms of the pKsub(A) of the extractant and the steric hindrance within the extractant. (author)

  17. Phase Diagram in a Random Mixture of Two Antiferromagnets with Competing Spin Anisotropies. I

    Science.gov (United States)

    Someya, Yoshiko

    1981-12-01

    The phase diagram of a random mixture of two antiferromagnets with competing spin anisotropies (A1-xBx) has been analyzed by extending the theory of Matsubara and Inawashiro, and Oguchi and Ishikawa. In the model assumed, the anisotropy energies are expressed by the anisotropic exchange interactions. According to this formulation, it has been shown that the concentration dependence of TN becomes a function of \\includegraphics{dummy.eps}, where P, Q=A, B; SP is a magnitude of P-spin, and JPQη is a η component of exchange integral between P- and Q-spin). Further, the phase boundary between an AF phase and an OAF (oblique antiferromagnetic) phase at T{=}0 K has been shown to be determined by α({\\equiv}SB/SA), if \\includegraphics{dummy.eps} are given. The obtained phase diagrams for Fe1-xCoxCl2, K2Mn1-xFexF4 and Fe1-xCoxCl2\\cdot2H2O are compared with the experimental ones.

  18. Identification of the 1s2s2p 4P5/2-->1s22s 2S1/2 magnetic quadrupole inner-shell satellite line in the Ar16+ K-shell x-ray spectrum

    Science.gov (United States)

    Beiersdorfer, P.; Bitter, M.; Hey, D.; Reed, K. J.

    2002-09-01

    We have identified the dipole-forbidden 1s2s2p 4P5/2-->1s22s 2S1/2 transition in lithiumlike Ar15+ in high-resolution K-shell x-ray emission spectra recorded at the Livermore EBIT-II electron-beam ion trap and the Princeton National Spherical Tokamak Experiment. Unlike other Ar15+ satellite lines, which can be excited by dielectronic recombination, the line is exclusively excited by electron-impact excitation. Its predicted radiative rate is comparable to that of the well-known 1s2p 3P1-->1s2 1S0 magnetic quadrupole transition in heliumlike Ar16+. As a result, it can also only be observed in low-density plasma. We present calculations of the electron-impact excitation cross sections of the innershell excited Ar15+ satellite lines, including the magnetic sublevels needed for calculating the linear line polarization. We compare these calculations to the relative magnitudes of the observed 1s2s2p-->1s22s transitions and find good agreement, confirming the identification of the lithiumlike 1s2s2p 4P5/2-->1s22s 2S1/2 magnetic quadrupole line.

  19. Two-phase systems. Fundamentals and industrial applications

    International Nuclear Information System (INIS)

    Woillez, Jacques

    2014-01-01

    Two-phase flows are omnipresent in industrial processes in different sectors with the behaviour and control of non-mixing mixtures of gas and liquids, of several liquids, of solids and fluids which are present in the production of raw materials, in the environment, in energy production, in chemistry, in pharmaceutical or food industry. The author presents the fundamentals elements which are needed to perform hardware predictive calculations and to understand typical phenomena associated with these flows. The chapters address fluids mechanics (movement equations, Bernoulli equation, load losses, turbulence, heat exchange coefficients, thermodynamics, compressible flows), two-phase systems (characteristic values, modes of appearance of two-phase flows, conduct flows, suspension mechanics, mass transfers, similarity, numerical simulation), the applications (energy production, agitation and mixing, phase separation, sprays), and peculiar phenomena (Marangoni effect, the tea cup effect, entry jets, water hammer effect, sound speed, two-phase pumping, fluidization)

  20. Pressure-induced irreversible metallization accompanying the phase transitions in S b2S3

    Science.gov (United States)

    Dai, Lidong; Liu, Kaixiang; Li, Heping; Wu, Lei; Hu, Haiying; Zhuang, Yukai; Yang, Linfei; Pu, Chang; Liu, Pengfei

    2018-01-01

    We have revealed S b2S3 to have two phase transitions and to undergo metallization using a diamond anvil cell at around 5.0, 15.0, and 34.0 GPa, respectively. These results were obtained on the basis of high-pressure Raman spectroscopy, temperature-dependent conductivity measurements, atomic force microscopy, high-resolution transmission electron microscopy, and first-principles calculations. The first phase transition at ˜5.0 GPa is an isostructural phase transition, which is manifested in noticeable changes in five Raman-active modes and the slope of the conductivity because of a change in the electronic structure. The second pressure-induced phase transition was characterized by a discontinuous change in the slope of conductivity and a new low-intensity Raman mode at ˜15.0 GPa . Furthermore, a semiconductor-to-metal transition was found at ˜34.0 GPa , which was accompanied by irreversible metallization, and it could be attributed to the permanently plastic deformation of the interlayer spacing. This high-pressure behavior of S b2S3 will help us to understand the universal crystal structure evolution and electrical characteristics for A2B3 -type compounds, and to facilitate their application in electronic devices.

  1. Direct numerical simulation of reactor two-phase flows enabled by high-performance computing

    Energy Technology Data Exchange (ETDEWEB)

    Fang, Jun; Cambareri, Joseph J.; Brown, Cameron S.; Feng, Jinyong; Gouws, Andre; Li, Mengnan; Bolotnov, Igor A.

    2018-04-01

    Nuclear reactor two-phase flows remain a great engineering challenge, where the high-resolution two-phase flow database which can inform practical model development is still sparse due to the extreme reactor operation conditions and measurement difficulties. Owing to the rapid growth of computing power, the direct numerical simulation (DNS) is enjoying a renewed interest in investigating the related flow problems. A combination between DNS and an interface tracking method can provide a unique opportunity to study two-phase flows based on first principles calculations. More importantly, state-of-the-art high-performance computing (HPC) facilities are helping unlock this great potential. This paper reviews the recent research progress of two-phase flow DNS related to reactor applications. The progress in large-scale bubbly flow DNS has been focused not only on the sheer size of those simulations in terms of resolved Reynolds number, but also on the associated advanced modeling and analysis techniques. Specifically, the current areas of active research include modeling of sub-cooled boiling, bubble coalescence, as well as the advanced post-processing toolkit for bubbly flow simulations in reactor geometries. A novel bubble tracking method has been developed to track the evolution of bubbles in two-phase bubbly flow. Also, spectral analysis of DNS database in different geometries has been performed to investigate the modulation of the energy spectrum slope due to bubble-induced turbulence. In addition, the single-and two-phase analysis results are presented for turbulent flows within the pressurized water reactor (PWR) core geometries. The related simulations are possible to carry out only with the world leading HPC platforms. These simulations are allowing more complex turbulence model development and validation for use in 3D multiphase computational fluid dynamics (M-CFD) codes.

  2. Investigation of two-phase liquid-metal magnetohydrodynamic power systems

    International Nuclear Information System (INIS)

    Amend, W.E.; Fabris, G.; Cutting, J.

    1975-01-01

    A two-phase Liquid-Metal MHD (LMMHD) system is under development at the Argonne National Laboratory, and results are presented for detailed cycle analysis and systems studies, the experimental facility, and the thermal and magneto fluid mechanics problems encountered. The studies indicate that the LMMHD cycle will operate efficiently in the temperature range of 1000-1600 0 F (50 percent efficiency with a maximum cycle temperature of 1600 0 F) and is therefore potentially compatible with many advanced heat sources under development such as the LMFBR, fluidized-bed coal combustor, HTGCR and the fusion reactor. Of special interest is the coupling to the LMFBR thereby eliminating the costly, potentially hazardous liquid-metal/water interface. The results of detailed parametric studies of the heat transfer interfaces between an LMMHD power cycle and an LMFBR and a steam bottoming plant are described. Experimental evaluation of the two-phase LMMHD generator was performed in an ambient temperature NaK--N 2 facility at ANL. Results of these experiments, performed to determine the operating characteristics of the device as a function of the various independent parameters and to investigate two-phase flow, are given. (U.S.)

  3. Two-dimensional phase fraction charts

    International Nuclear Information System (INIS)

    Morral, J.E.

    1984-01-01

    A phase fraction chart is a graphical representation of the amount of each phase present in a system as a function of temperature, composition or other variable. Examples are phase fraction versus temperature charts used to characterize specific alloys and as a teaching tool in elementary texts, and Schaeffler diagrams used to predict the amount of ferrite in stainless steel welds. Isothermal-transformation diagrams (TTT diagrams) are examples that give phase (or microconstituent) amount versus temperature and time. The purpose of this communication is to discuss the properties of two-dimensional phase fraction charts in more general terms than have been reported before. It is shown that they can represent multi-component, multiphase equilibria in a way which is easier to read and which contains more information than the isotherms and isopleths of multi-component phase diagrams

  4. Quasimolecular emission near the Xe(5p 56s 1,3 P 1 - 5p 6 1 S 0) and Kr (4p 55s 1,3 P 1 - 4p 6 1 S 0) resonance lines induced by collisions with He atoms

    Science.gov (United States)

    Alekseeva, O. S.; Devdariani, A. Z.; Grigorian, G. M.; Lednev, M. G.; Zagrebin, A. L.

    2017-02-01

    This study is devoted to the theoretical investigation of the quasimolecular emission of Xe*-He and Kr*-He collision pairs near the Xe (5p 56s 1,3 P 1 - 5p 6 1 S 0) and Kr (4p 55s 1,3 P 1 - 4p 6 1 S 0) resonance atomic lines. The potential curves of the quasimolecules Xe(5p 56s) + He and Kr(4p 55s) + He have been obtained with the use of the effective Hamiltonian and pseudopotential methods. Based on these potential curves the processes of quasimolecular emission of Xe*+He and Kr*+He mixtures have been considered and the spectral distributions I(ħΔω) of photons emitted have been obtained in the framework of quasistatic approximation.

  5. Crystal structure of bis-[(acetato-κO)(imidazolidine-2-thione-κS)bis-(tri-phenyl-phosphane-κP)silver(I)] di-μ-imidazol-idine-2-thione-κ(4) S:S-bis-[(imidazol-id-ine-2-thione-κS)bis-(tri-phenyl-phosphane-κP)silver(I)] di-acetate aceto-nitrile disolvate tetra-hydrate.

    Science.gov (United States)

    Nimthong-Roldán, Arunpatcha; Ratthiwan, Janejira; Lakmas, Sawanya; Wattanakanjana, Yupa

    2016-04-01

    In the title compound, [Ag2(C3H6N2S)4(C18H15P)2](C2H3O2)2·[Ag(C2H3O2)(C3H6N2S)(C18H15P)2]2·2C2H3N·4H2O, the Ag(I) ion in the mononuclear neutral complex exhibits a distorted tetra-hedral environment with coordination by two P atoms from tri-phenyl-phosphane (PPh3) ligands, one S atom of an imidazolidine-2-thione (etu) ligand and one O atom of an acetate anion. The binuclear cationic complex comprises two inversion-related [Ag(C3H6N2S)2(C18H15P)] units with Ag(I) ions bridged by two S atoms from etu ligands forming a four-membered Ag-S-Ag-S ring. Each Ag(I) ion is coordinated by a P atom of a PPh3 ligand, two S atoms of bridging etu ligands and the terminal S atom of an etu ligand in a distorted tetra-hedral environment. In the crystal, the mononuclear complex is linked to lattice water mol-ecules through O-H⋯O and N-H⋯O hydrogen bonds, forming a chain along [100]. In addition, the binuclear complex mol-ecules are connected to acetate anions and lattice water mol-ecules via O-H⋯O, N-H⋯O and O-H⋯S hydrogen bonds, also along [100].

  6. Relative permeabilities of supercritical CO2 and brine in carbon sequestration by a two-phase lattice Boltzmann method

    Science.gov (United States)

    Xie, Jian.-Fei.; He, S.; Zu, Y. Q.; Lamy-Chappuis, B.; Yardley, B. W. D.

    2017-08-01

    In this paper, the migration of supercritical carbon dioxide (CO2) in realistic sandstone rocks under conditions of saline aquifers, with applications to the carbon geological storage, has been investigated by a two-phase lattice Boltzmann method (LBM). Firstly the digital images of sandstone rocks were reproduced utilizing the X-ray computed microtomography (micro-CT), and high resolutions (up to 2.5 μm) were applied to the pore-scale LBM simulations. For the sake of numerical stability, the digital images were "cleaned" by closing the dead holes and removing the suspended particles in sandstone rocks. In addition, the effect of chemical reactions occurred in the carbonation process on the permeability was taken into account. For the wetting brine and non-wetting supercritical CO2 flows, they were treated as the immiscible fluids and were driven by pressure gradients in sandstone rocks. Relative permeabilities of brine and supercritical CO2 in sandstone rocks were estimated. Particularly the dynamic saturation was applied to improve the reliability of the calculations of the relative permeabilities. Moreover, the effects of the viscosity ratio of the two immiscible fluids and the resolution of digital images on the relative permeability were systematically investigated.

  7. S P Panda

    Indian Academy of Sciences (India)

    Home; Journals; Sadhana. S P Panda. Articles written in Sadhana. Volume 40 Issue 1 February 2015 pp 89-106 Electrical and Computer Sciences. Experimental validation of waveform relaxation technique for power system controller testing · S P Panda K A Salunkhe A M Kulkarni · More Details Abstract Fulltext PDF.

  8. High pH mobile phase effects on silica-based reversed-phase high-performance liquid chromatographic columns

    NARCIS (Netherlands)

    Kirkland, J.J.; Straten, van M.A.; Claessens, H.A.

    1995-01-01

    Aqueous mobile phases above pH 8 often cause premature column failure, limiting the utility of silica-based columns for applications requiring high pH. Previous studies suggest that covalently bound silane ligands are hydrolyzed and removed by high-pH mobile phases. However, we found that the

  9. Biogasification of solid wastes by two-phase anaerobic fermentation

    International Nuclear Information System (INIS)

    Ghosh, S.; Vieitez, E.R.; Liu, T.; Kato, Y.

    1997-01-01

    Municipal, industrial and agricultural solid wastes, and biomass deposits, cause large-scale pollution of land and water. Gaseous products of waste decomposition pollute the air and contribute to global warming. This paper describes the development of a two-phase fermentation system that alleviates methanogenic inhibition encountered with high-solids feed, accelerates methane fermentation of the solid bed, and captures methane (renewable energy) for captive use to reduce global warming. The innovative system consisted of a solid bed reactor packed with simulated solid waste at a density of 160 kg/m 3 and operated with recirculation of the percolated culture (bioleachate) through the bed. A rapid onset of solids hydrolysis, acidification, denitrification and hydrogen gas formation was observed under these operating conditions. However, these fermentative reactions stopped at a total fatty acids concentration of 13,000 mg/l (as acetic) at pH 5, with a reactor head-gas composition of 75 percent carbon dioxide, 20 percent nitrogen, 2 percent hydrogen and 3 percent methane. Fermentation inhibition was alleviated by moving the bioleachate to a separate methane-phase fermenter, and recycling methanogenic effluents at pH 7 to the solid bed. Coupled operation of the two reactors promoted methanogenic conversion of the high-solids feed. (author)

  10. Two-phase cross-flow-induced forces acting on a circular cylinder

    International Nuclear Information System (INIS)

    Hara, F.

    1982-01-01

    This paper clarifies the characteristics of unsteady flow-induced lift and drag forces acting on a circular cylinder immersed perpendicular to a two-phase bubbly air-water flow, in conjunction with Karman vortex shedding and pressure fluctuations. Experimental results presented show that Karman vortex shedding disappears over a certain value of air concentration in the two-phase flow. Related to this disappearance, flow-induced forces are rather small and periodical in low air concentration but become very large and random in higher air concentration. 7 refs

  11. Phase Transition and Physical Properties of InS

    Science.gov (United States)

    Wang, Hai-Yan; Li, Xiao-Feng; Xu, Lei; Li, Xu-Sheng; Hu, Qian-Ku

    2018-02-01

    Using the crystal structure prediction method based on particle swarm optimization algorithm, three phases (Pnnm, C2/m and Pm-3m) for InS are predicted. The new phase Pm-3m of InS under high pressure is firstly reported in the work. The structural features and electronic structure under high pressure of InS are fully investigated. We predicted the stable ground-state structure of InS was the Pnnm phase and phase transformation of InS from Pnnm phase to Pm-3m phase is firstly found at the pressure of about 29.5 GPa. According to the calculated enthalpies of InS with four structures in the pressure range from 20 GPa to 45 GPa, we find the C2/m phase is a metastable phase. The calculated band gap value of about 2.08 eV for InS with Pnnm structure at 0 GPa agrees well with the experimental value. Moreover, the electronic structure suggests that the C2/m and Pm-3m phase are metallic phases. Supported by the National Natural Science Foundation of China under Grant Nos. 11404099, 11304140, 11147167 and Funds of Outstanding Youth of Henan Polytechnic University, China under Grant No. J2014-05

  12. Analysis of water hammer in two-component two-phase flows

    International Nuclear Information System (INIS)

    Warde, H.; Marzouk, E.; Ibrahim, S.

    1989-01-01

    The water hammer phenomena caused by a sudden valve closure in air-water two-phase flows must be clarified for the safety analysis of LOCA in reactors and further for the safety of boilers, chemical plants, pipe transport of fluids such as petroleum and natural gas. In the present work water hammer phenomena caused by sudden valve closure in two-component two-phase flows are investigated theoretically and experimentally. The phenomena are more complicated than in single phase-flows due to the fact of the presence of compressible component. Basic partial differential equations based on a one-dimensional homogeneous flow model are solved by the method of characteristic. The analysis is extended to include friction in a two-phase mixture depending on the local flow pattern. The profiles of the pressure transients, the propagation velocity of pressure waves and the effect of valve closure on the transient pressure are found. Different two-phase flow pattern and frictional pressure drop correlations were used including Baker, Chesholm and Beggs and Bril correlations. The effect of the flow pattern on the characteristic of wave propagation is discussed primarily to indicate the effect of void fraction on the velocity of wave propagation and on the attenuation of pressure waves. Transient pressure in the mixture were recorded at different air void fractions, rates of uniform valve closure and liquid flow velocities with the aid of pressure transducers, transient wave form recorders interfaced with an on-line pc computer. The results are compared with computation, and good agreement was obtained within experimental accuracy

  13. Vaporization study on vanadium monoxide and two-phase mixture of vanadium and vanadium monoxide by mass-spectrometric method

    International Nuclear Information System (INIS)

    Banchorndhevakul, W.; Matsui, Tsuneo; Naito, Keiji

    1986-01-01

    The vapor pressures over single phase vanadium monoxide VO 1.022 (s) and the two-phase mixture of vanadium metal (β phase) and vanadium monoxide were measured by mass-spectrometric method in the temperature range of 1,803 ∼ 1,990 and 1,703 ∼ 1,884 K, respectively. The main gas species over both systems were found to be VO(g) and V(g). The vapor pressure of VO(g) over the two-phase mixture of V(s) and VO(s) was a little lower than that over single phase VO(s). The vapor pressure of V(g) over the two-phase mixture was nearly equal to that over single phase. From the vapor pressure data, the enthalpies of vaporization, the enthalpies of formation for VO(g) and V(g) and the dissociation energy of VO(g) were determined. The oxygen partial pressure was calculated as a function of temperature from the vapor pressures of VO(g) and V(g), from which the partial molar enthalpies and entropies of oxygen in both systems were obtained. (author)

  14. Beeswax as phase change material to improve solar panel’s performance

    Science.gov (United States)

    Thaib, R.; Rizal, S.; Riza, M.; Mahlia, T. M. I.; Rizal, T. A.

    2018-02-01

    One of the main obstacles faced during the operation of photovoltaic (PV) panels was overheating due to excessive solar radiation and high ambient temperatures. In this research, investigates the use of beeswax phase change materials (PCM) to maintain the temperature of the panels close to ambient. Solar panels used in this study has 839 mm length, 537 mm wide, and 50 mm thick, with maximum output power at 50 W. During the study, there were two solar panels was evaluated, one without phase change material while the other one was using beeswax phase change material. Solar panels were mounted at 15° slope. Variables observed was the temperature of solar panel’s surface, output voltage and current that produced by PV panels, wind speed around solar panels, and solar radiation. The observation was started at 07:00 am and ended at 06:00 pm. The research shows that maximum temperature of solar panels surface without phase change material is ranging between 46-49 °C, and electrical efficiency is about 7.2-8.8%. Meanwhile, for solar panels with beeswax phase change material, the maximum temperature solar panels surface is relatively low ranging between 33-34 °C, and its electrical efficiency seems to increase about 9.1-9.3%.

  15. Sphingosine-1-phosphate (S1P) activates STAT3 to protect against de novo acute heart failure (AHF).

    Science.gov (United States)

    Deshpande, Gaurang P; Imamdin, Aqeela; Lecour, Sandrine; Opie, Lionel H

    2018-03-01

    Acute heart failure (AHF) is a burden disease, with high mortality and re-hospitalisations. Using an ex-vivo model of AHF, we have previously reported that sphingosine-1-phosphate (S1P) confers cardioprotection. However, the mechanisms remain to be elucidated. In the present study, we aimed to examine the role of the cardioprotective signal transducer and activator of transcription 3 (STAT3) in S1P mediated improved functional recovery in AHF. Isolated hearts from male Long-Evans rats were subjected to hypotensive AHF for 35 min followed by a recovery phase of 30 min (n ≥ 4/group). S1P (10 nM) was given during either the hypotensive or the recovery phase with/without an inhibitor of STAT3, AG490. Functional parameters were recorded throughout the experiment. Following an AHF insult, S1P, given during the recovery phase, improved the heart rate (HR) compared to the control (175.2 ± 30.7 vs. 71.6 ± 27.4 beats per minute (BPM); p S1P abolished the cardioprotective effect of S1P (42.3 ± 17.1 vs. 148.8 ± 26.4 BPM for S1P; p S1P protects in an ex-vivo rat heart model of AHF by activation of STAT3 and provide further evidence for the usage of S1P as a potential therapy in patients suffering from AHF. Copyright © 2018 Elsevier Inc. All rights reserved.

  16. Two-phase flow instabilities in a silicon microchannels heat sink

    International Nuclear Information System (INIS)

    Bogojevic, D.; Sefiane, K.; Walton, A.J.; Lin, H.; Cummins, G.

    2009-01-01

    Two-phase flow instabilities are highly undesirable in microchannels-based heat sinks as they can lead to temperature oscillations with high amplitudes, premature critical heat flux and mechanical vibrations. This work is an experimental study of boiling instabilities in a microchannel silicon heat sink with 40 parallel rectangular microchannels, having a length of 15 mm and a hydraulic diameter of 194 μm. A series of experiments have been carried out to investigate pressure and temperature oscillations during the flow boiling instabilities under uniform heating, using water as a cooling liquid. Thin nickel film thermometers, integrated on the back side of a heat sink with microchannels, were used in order to obtain a better insight related to temperature fluctuations caused by two-phase flow instabilities. Flow regime maps are presented for two inlet water temperatures, showing stable and unstable flow regimes. It was observed that boiling leads to asymmetrical flow distribution within microchannels that result in high temperature non-uniformity and the simultaneously existence of different flow regimes along the transverse direction. Two types of two-phase flow instabilities with appreciable pressure and temperature fluctuations were observed, that depended on the heat to mass flux ratio and inlet water temperature. These were high amplitude/low frequency and low amplitude/high frequency instabilities. High speed camera imaging, performed simultaneously with pressure and temperature measurements, showed that inlet/outlet pressure and the temperature fluctuations existed due to alternation between liquid/two-phase/vapour flows. It was also determined that the inlet water subcooling condition affects the magnitudes of the temperature oscillations in two-phase flow instabilities and flow distribution within the microchannels.

  17. Experimental-statistical model of liquid-phase epitaxy for InP/InGaAsP/InP heterostructures

    International Nuclear Information System (INIS)

    Vasil'ev, M.G.; Selin, A.A.; Shelyakin, A.A.

    1985-01-01

    A mathematic model of the process of liquid-phase epitaxy for double InP/InGaAsP/InP heterostructures is constructed using statistical methods of experiment planning. The analysis of the model shows that the degree of In-P system melt supercooling affects considerably the characteristics of double heterostructures

  18. Two-phase titration of cerium(3) by permanganate

    International Nuclear Information System (INIS)

    Lazarev, A.I.; Lazareva, V.I.; Gerko, V.V.

    1986-01-01

    Reaction of cerium (3) and permanganate was investigated at a room temperature depending on PH, concentrations of pyrophosphate, cerium (3), tetraphenylphosphonium and foreign compounds. Selective method of two-phase titration determination of cerium (3) by permanganate without using silver compounds, preliminary separation of chlorides, nitrates, was developed. The method was tested using alloys based on iron, nickel, REE, copper, cobalt (S r ≤0.008). Correctness is proved with method of standard additives

  19. Concatenation of Observed Grasp Phases with Observer’s Distal Movements: A Behavioural and TMS Study

    Science.gov (United States)

    De Stefani, Elisa; Innocenti, Alessandro; De Marco, Doriana; Gentilucci, Maurizio

    2013-01-01

    The present study aimed at determining how actions executed by two conspecifics can be coordinated with each other, or more specifically, how the observation of different phases of a reaching-grasping action is temporary related to the execution of a movement of the observer. Participants observed postures of initial finger opening, maximal finger aperture, and final finger closing of grasp after observation of an initial hand posture. Then, they opened or closed their right thumb and index finger (experiments 1, 2 and 3). Response times decreased, whereas acceleration and velocity of actual finger movements increased when observing the two late phases of grasp. In addition, the results ruled out the possibility that this effect was due to salience of the visual stimulus when the hand was close to the target and confirmed an effect of even hand postures in addition to hand apparent motion due to the succession of initial hand posture and grasp phase. In experiments 4 and 5, the observation of grasp phases modulated even foot movements and pronunciation of syllables. Finally, in experiment 6, transcranial magnetic stimulation applied to primary motor cortex 300 ms post-stimulus induced an increase in hand motor evoked potentials of opponens pollicis muscle when observing the two late phases of grasp. These data suggest that the observation of grasp phases induced simulation which was stronger during observation of finger closing. This produced shorter response times, greater acceleration and velocity of the successive movement. In general, our data suggest best concatenation between two movements (one observed and the other executed) when the observed (and simulated) movement was to be accomplished. The mechanism joining the observation of a conspecific’s action with our own movement may be precursor of social functions. It may be at the basis for interactions between conspecifics, and related to communication between individuals. PMID:24278395

  20. Industrial aspects of gas-liquid two-phase flow

    International Nuclear Information System (INIS)

    Hewitt, G.F.

    1977-01-01

    The lecture begins by reviewing the various types of plant in which two phase flow occurs. Specifically, boiling plant, condensing plant and pipelines are reviewed, and the various two phase flow problems occurring in them are described. Of course, many other kinds of chemical engineering plant involve two phase flow, but are somewhat outside the scope of this lecture. This would include distillation columns, vapor-liquid separators, absorption towers etc. Other areas of industrial two phase flow which have been omitted for space reasons from this lecture are those concerned with gas/solids, liquid/solid and liquid/liquid flows. There then follows a description of some of the two phase flow processes which are relevant in industrial equipment and where special problems occur. The topics chosen are as follows: (1) pressure drop; (2) horizontal tubes - separation effects non-uniformites in heat transfer coefficient, effect of bends on dryout; (3) multicomponent mixtures - effects in pool boiling, mass transfer effects in condensation and Marangoni effects; (4) flow distribution - manifold problems in single phase flow, separation effects at a single T-junction in two phase flow and distribution in manifolds in two phase flow; (5) instability - oscillatory instability, special forms of instability in cryogenic systems; (6) nucleate boiling - effect of variability of surface, unresolved problems in forced convective nucleate boiling; and (7) shell side flows - flow patterns, cross flow boiling, condensation in cross flow

  1. Measurement of void fraction and bubble size distribution in two-phase flow system

    International Nuclear Information System (INIS)

    Huahun, G.

    1987-01-01

    The importance of study two phase flow parameter and microstructure has appeared increasingly, with the development of two-phase flow discipline. In the paper, the measurement methods of several important microstructure parameter in a two phase flow vertical channel have been studied. Using conductance probe the two phase flow pattern and the average void fraction have been measured previously by the authors. This paper concerns microstructure of the bubble size distribution and local void fraction. The authors studied the methods of measuring bubble velocity, size distribution and local void fraction using double conductance probes and a set of apparatus. Based on our experiments and Yoshihiro work, a formula of calculated local void fraction has been deduced by using the statistical characteristics of bubbles in two phase flow and the relation between calculated bubble size and voltage has been determined. Finally the authors checked by using photograph and fast valve, which is classical but reliable. The results are the same with what has been studied before

  2. The Effect of Shoe Insole Stiffness on Leg Stiffness during Stance Phase of Running in Two Different Speeds ‎among Active Men

    Directory of Open Access Journals (Sweden)

    Zeinab Tazike-Lemeski

    2016-08-01

    Full Text Available Introduction: The effect of shoe insoles with different characteristics and in different running speeds on lower-limb stiffness is still ‎controversial. The aim of this study was to investigate the effect of two types of insoles (soft and semi-rigid in two ‎different running speeds on leg stiffness during stance phase of running among active men.‎ Materials and Methods: ‎15 male students without any background of lower extremity injury were selected. Subjects were asked to run with ‎two controlled velocities of 3.0 ± 0.2 and 5.0 ± 0.1 m/s in control and insole conditions (soft and semi-rigid on a ‎force plate, placed on the middle of 15-meter runway. The cinematics and cinetics of motion were measured and ‎calculated using 5 video cameras and one force plate. The leg stiffness was achieved via dividing the vertical ‎ground reaction force by leg compression. Two-factor repeated measures ANOVA was used to test the hypothesis at ‎the significance level of P £ 0.050.‎ Results: There was a significant difference between the two types of insoles on leg stiffness. In fact, semi-rigid insole significantly increased leg stiffness (P < 0.001. However, this discrepancy was not related to the running speed (P = 0.999. In addition, there was no significant difference between the two different speeds on leg stiffness (P = 0.632. Conclusion: It seems that the increase in shoe insole stiffness may increase the leg stiffness. Furthermore, the effect of insole ‎stiffness is not related to the running speed, and leg stiffness will remains constant in low to medium running speeds.‎

  3. Analytical study of solids-gas two phase flow

    International Nuclear Information System (INIS)

    Hosaka, Minoru

    1977-01-01

    Fundamental studies were made on the hydrodynamics of solids-gas two-phase suspension flow, in which very small solid particles are mixed in a gas flow to enhance the heat transfer characteristics of gas cooled high temperature reactors. Especially, the pressure drop due to friction and the density distribution of solid particles are theoretically analyzed. The friction pressure drop of two-phase flow was analyzed based on the analytical result of the single-phase friction pressure drop. The calculated values of solid/gas friction factor as a function of solid/gas mass loading are compared with experimental results. Comparisons are made for Various combinations of Reynolds number and particle size. As for the particle density distribution, some factors affecting the non-uniformity of distribution were considered. The minimum of energy dispersion was obtained with the variational principle. The suspension density of particles was obtained as a function of relative distance from wall and was compared with experimental results. It is concluded that the distribution is much affected by the particle size and that the smaller particles are apt to gather near the wall. (Aoki, K.)

  4. Optical nonlinearities of colloidal InP@ZnS core-shell quantum dots probed by Z-scan and two-photon excited emission

    International Nuclear Information System (INIS)

    Wawrzynczyk, Dominika; Szeremeta, Janusz; Samoc, Marek; Nyk, Marcin

    2015-01-01

    Spectrally resolved nonlinear optical properties of colloidal InP@ZnS core-shell quantum dots of various sizes were investigated with the Z-scan technique and two-photon fluorescence excitation method using a femtosecond laser system tunable in the range from 750 nm to 1600 nm. In principle, both techniques should provide comparable results and can be interchangeably used for determination of the nonlinear optical absorption parameters, finding maximal values of the cross sections and optimizing them. We have observed slight differences between the two-photon absorption cross sections measured by the two techniques and attributed them to the presence of non-radiative paths of absorption or relaxation. The most significant value of two-photon absorption cross section σ 2 for 4.3 nm size InP@ZnS quantum dot was equal to 2200 GM, while the two-photon excitation action cross section σ 2 Φ was found to be 682 GM at 880 nm. The properties of these cadmium-free colloidal quantum dots can be potentially useful for nonlinear bioimaging

  5. Two applications of Berry's phase in fermionic field theory

    International Nuclear Information System (INIS)

    Goff, W.E.

    1989-01-01

    When quantized fermions are coupled to a background field, nontrivial effects may arise due to the geometry and/or topology of the space of background field configurations. In this thesis, two examples of Berry's geometrical phase in a fermionic sea are studied: the anomalous commutator in gauge field theory and the intrinsic orbital angular momentum in superfluid 3 He-A. Chapter 1 is a brief introduction. Chapter 2 reviews Berry's Phase and several toy models. Effective actions are calculated for two models in gradient expansions and the role of a geometric term is discussed. Chapter 3 investigates the anomalous commutator in the generators of gauge symmetry in field theory. Using an idea introduced by Sonoda, the Berry phase of the vacuum state is found to be the sum of the Berry phases of the individual states in the sea plus a piece due to the infinite nature of the Dirac sea. The latter is the anomalous commutator. Also found is a relative minus sign between the commutator of the total gauge symmetry generators and the commutator of the fermionic charge generators. Examples are given. In Chapter 4, a geometric way of deriving the intrinsic orbital angular momentum term in the 3 He-A equations of motion is presented. Homogeneous, adiabatically evolving textures at zero temperature are found to pick up a nonzero groundstate Berry phase, where the ground state is taken to be a filled sea of Bogoliubov quasiparticles. Interpreting the phase as a Wess-Zumino effective action for the condensate provides a geometric origin for the intrinsic angular momentum. The idea of a ground-state phase is then extended to other gap functions and a more general result is obtained. Chapter 5 concludes with a discussion of the possibility of unifying the two problems in a more general framework and directions for further work

  6. The role of electrolyte pH on phase evolution and magnetic properties of CoFeW codeposited films

    International Nuclear Information System (INIS)

    Ghaferi, Z.; Sharafi, S.; Bahrololoom, M.E.

    2016-01-01

    Highlights: • Deposition tends to anomalous-induced fashion at higher pH values. • The structure of the coatings depend on electrolyte pH effectively. • Grain size of two-phase structure films is lower than single-phase solid solutions. • Coercivity of the coatings changed by tungsten content and surface defects. • The highest pH value produced coating with superior magnetic behaviour. - Abstract: In this research, nanocrystalline Co–Fe–W alloy coatings were electrodeposited from a citrate-borate bath. The influence of electrolyte pH on the morphology, microstructure and magnetic properties of these films was also studied. By increasing pH value, the amount of iron content increased from 30 to 55 wt.% which indicates anomalous fashion at higher pH electrolytes. X-ray diffraction patterns showed that the structure of these films depend on electrolyte pH effectively. However, two-phase structure coatings showed smaller average grain size compared with one- phase solid solutions. Vibrating sample magnetometer measurements indicated that the coercivity of the coatings was in the range of 21–76 Oe. However, the highest pH value produced coating with superior magnetic behaviour. Microhardness of the coatings reached its maximum value at about 260HV which is referred to the highest tungsten content.

  7. High-pressure phases of S, Se, and P hydrides and their superconducting properties. Predictions from ab-initio theory

    Energy Technology Data Exchange (ETDEWEB)

    Gross, E.K.U. [Max Planck Institute of Microstructure Physics, Halle (Saale) (Germany)

    2016-07-01

    The quest for novel high-temperature superconductors in the family of hydrogen-rich compounds has recently been crowned with the experimental discovery of a record critical temperature of 190 K in a hydrogen-sulfur compound at 200 GPa. In the present contribution, we investigate the phase diagram of the H-S system, comparing the stability of H{sub n}S (n = 1,2,3,4) by means of the minima hopping method for structure prediction. Our extensive crystal structure search confirms the H{sub 3}S stoichiometry as the most stable configuration at high pressure. Superconducting properties are calculated using the fully ab-initio parameter-free approach of density functional theory for superconductors. We find a T{sub c} of 180 K at 200 GPa, in excellent agreement with experiment. We also show that Se-H has a phase diagram similar to its sulfur counterpart. We predict H{sub 3}Se to be superconducting at temperatures higher than 120 K at 100 GPa. We furthermore investigate the phase diagram of PH{sub n} (n = 1,2,3,4,5,6). The results of our crystal-structure search do not support the existence of thermodynamically stable PH{sub n} compounds, which exhibit a tendency for elemental decomposition at high pressure. Although the lowest energy phases of PH{sub n=1,2,3} display T{sub c} values comparable to experiment, it remains uncertain if the measured values of T{sub c} can be fully attributed to a phase-pure compound of PH{sub n}.

  8. Observation of the spin gap in a S=1/2 alternating chain compound, high pressure phase of (VO)2P2O7

    International Nuclear Information System (INIS)

    Saito, Takashi; Azuma, Masaki; Fujita, Masaki; Takano, Mikio

    2001-01-01

    Inelastic neutron scattering data were collected on the high pressure phase of (VO) 2 P 2 O 7 , a S=1/2 Heisenberg antiferromagnetic alternating chain compound. The existence of a spin gap was confirmed, and the size was determined to be Δ=2.15(6) meV (=25.0(7) K). The theoretically predicted second gap (Δ'=2Δ) owing to a 2-magnon bound state was not observed. This is consistent with the high field magnetization measurement reported previously. (author)

  9. Investigation of the propagation characteristics in turbulent dispersed two-phase flow

    International Nuclear Information System (INIS)

    Sami, S.M.

    1980-01-01

    The propagation characteristics of turbulent dispersed two-phase flows have been studied experimentally using the Pitot tube associated with a conical hot-film anemometer. It is found that the mixture velocity increases with decreasing volumetric mixing ratio of the air and water. The void fraction distribution shows homogeneity across the test section in the special case of fully developed boundary layer two-phase flow. An expression is obtained which relates the local mixture velocity to the local void fraction, gas and liquid densities, and volumetric gas-liquid ratio

  10. Evidence of the 2s2p(1P) doubly excited state in the harmonic generation spectrum of helium

    International Nuclear Information System (INIS)

    Ngoko Djiokap, J. M.; Starace, Anthony F.

    2011-01-01

    By solving the two-active-electron time-dependent Schroedinger equation in an intense, ultrashort laser field, we investigate evidence of electron correlations in the high-order harmonic generation spectrum of helium. As the frequency of the driving laser pulse varies from 4.6 to 6.6 eV, the 13th, 11th, and 9th harmonics sequentially become resonant with the transition between the ground state and the isolated 2s2p( 1 P) autoionizing state of helium, which dramatically enhances these harmonics and changes their profiles. When each of the 9th and 13th harmonics are in resonance with this autoionizing state, there is also a low-order multiphoton resonance with a Rydberg state, resulting in a particularly large enhancement of these harmonics relative to neighboring harmonics. When the 11th harmonic is in resonance with the 2s2p( 1 P) autoionizing state, the 13th harmonic is simultaneously in resonance with numerous higher-energy autoionizing states, resulting in a competition between these two harmonics for intensity. These results demonstrate that even electron correlations occurring over a narrow energy interval can have a significant effect on strong-field processes such as harmonic generation.

  11. A Phase-Controlled Optical Parametric Amplifier Pumped by Two Phase-Distorted Laser Beams

    International Nuclear Information System (INIS)

    Hong-Yan, Ren; Lie-Jia, Qian; Peng, Yuan; He-Yuan, Zhu; Dian-Yuan, Fan

    2010-01-01

    We theoretically study the phase characteristic of optical parametric amplification (OPA) or chirped pulse OPA (OPCPA) pumped by two phase-distorted laser beams. In the two-beam-pumped optical parametric amplification (TBOPA), due to spatial walk-off, both of the pump phase distortions will be partly transferred to signal in a single crystal so as to degrade the signal beam-quality, which will be more serious in high-energy OPCPA. An OPA configuration with a walkoff-compensated crystal pair is demonstrated for reducing the signal phase distortion experienced in the first stage and ensuring the signal phase independent of two pump phase distortions through the second crystal, hence maintaining the signal beam-quality. Such a TBOPA is similar to the conventional quantum laser amplifier by means of eliminating its sensitivity to the phase and number of the pump beams

  12. Slug flow transitions in horizontal gas/liquid two-phase flows. Dependence on channel height and system pressure for air/water and steam/water two-phase flows

    International Nuclear Information System (INIS)

    Nakamura, Hideo

    1996-05-01

    The slug flow transitions and related phenomena for horizontal two-phase flows were studied for a better prediction of two-phase flows that typically appear during the reactor loss-of-coolant accidents (LOCAs). For better representation of the flow conditions experimentally, two large-scaled facility: TPTF for high-pressure steam/water two-phase flows and large duct test facility for air/water two-phase flows, were used. The visual observation of the flow using a video-probe was performed in the TPTF experiments for good understanding of the phenomena. The currently-used models and correlations based mostly on the small-scale low-pressure experiments were reviewed and improved based on these experimental results. The modified Taitel-Dukler model for prediction of transition into slug flow from wavy flow and the modified Steen-Wallis correlation for prediction of onset of liquid entrainment from the interfacial waves were obtained. An empirical correlation for the gas-liquid interfacial friction factor was obtained further for prediction of liquid levels at wavy flow. The region of slug flow regime that is generally under influences of the channel height and system pressure was predicted well when these models and correlations were applied together. (author). 90 refs

  13. Two-phase gas bubble-liquid boundary layer flow along vertical and inclined surfaces

    International Nuclear Information System (INIS)

    Cheung, F.B.; Epstein, M.

    1985-01-01

    The behavior of a two-phase gas bubble-liquid boundary layer along vertical and inclined porous surfaces with uniform gas injection is investigated experimentally and analytically. Using argon gas and water as the working fluids, a photographical study of the two-phase boundary layer flow has been performed for various angles of inclination ranging from 45 0 to 135 0 and gas injection rates ranging from 0.01 to 0.1 m/s. An integral method has been employed to solve the system of equations governing the two-phase motion. The effects of the gas injection rate and the angle of inclination on the growth of the boundary layer have been determined. The predicted boundary layer thickness is found to be in good agreement with the experimental results. The calculated axial liquid velocity and the void fraction in the two-phase region are also presented along with the observed flow behavior

  14. Results of two-phase natural circulation in hot-leg U-bend simulation experiments

    International Nuclear Information System (INIS)

    Ishii, M.; Lee, S.Y.; Abou El-Seoud, S.

    1987-01-01

    In order to study the two-phase natural circulation and flow termination during a small break loss of coolant accident in LWR, simulation experiments have been performed using two different thermal-hydraulic loops. The main focus of the experiment was the two-phase flow behavior in the hot-leg U-bend typical of BandW LWR systems. The first group of experiments was carried out in the nitrogen gas-water adiabatic simulation loop and the second in the Freon 113 boiling and condensation loop. Both of the loops have been designed as a flow visualization facility and built according to the two-phase flow scaling criteria developed under this program. The nitrogen gas-water system has been used to isolate key hydrodynamic phenomena such as the phase distribution, relative velocity between phases, two-phase flow regimes and flow termination mechanisms, whereas the Freon loop has been used to study the effect of fluid properties, phase changes and coupling between hydrodynamic and heat transfer phenomena. Significantly different behaviors have been observed due to the non-equilibrium phase change phenomena such as the flashing and condensation in the Freon loop. The phenomena created much more unstable hydrodynamic conditions which lead to cyclic or oscillatory flow behaviors

  15. Two phase cooling for superconducting magnets

    International Nuclear Information System (INIS)

    Eberhard, P.H.; Gibson, G.A.; Green, M.A.; Ross, R.R.; Smits, R.G.

    1986-01-01

    Comments on the use of two phase helium in a closed circuit tubular cooling system and some results obtained with the TPC superconducting magnet are given. Theoretical arguments and experimental evidence are given against a previously suggested method to determine helium two phase flow regimes. Two methods to reduce pressure in the magnet cooling tubes during quenches are discussed; 1) lowering the density of helium in the magnet cooling tubes and 2) proper location of pressure relief valves. Some techniques used to protect the refrigerator from too much cold return gas are also mentioned

  16. Orthogonality Catastrophe as a prerequisite for the irreversible decay of the global relative phase of a two-component Bose-Einstein condensate

    Science.gov (United States)

    Birman, Joseph L.; Kuklov, A. B.

    2001-05-01

    The concept of the orthogonality catastrophe (OC), which has been introduced previously for one component condensate ( A.B. Kuklov, J.L. Birman, PRA 63), 013609 (2001), is applied to the two-component condensate. The evolution of the global relative phase, which is created by the rf-pulse, is studied under the condition of no exchange of bosons between the components after the pulse. It is shown that the normal component does not induce the OC. Instead, it produces a reversible thermal dephasing, which competes with the quantum phase diffusion (QPD) effect (E.M.Wright, et al, PRL 77), 2158(1996). The thermal dephasing results from the thermal ensemble averaging, and the corresponding dephasing rate is controlled by the two-body interaction and temperature as well as by the closeness to the intrinsic su(2) symmetry, so that no dephasing exists in the case of the exact symmetry (A.B. Kuklov, J.L. Birman, PRL 85), 5488 (2000). The reversible nature of the thermal dephasing as well as of the QPD can be revealed in the atomic echo effect. The role of external noise in erasing the phase memory is discussed as well.

  17. Wedge-shaped parenchymal enhancement peripheral to the hepatic hemangioma : two-phase spiral CT findings

    International Nuclear Information System (INIS)

    Kim, Kyoung Won; Kim, Tae Kyoung; Han, Joon Koo; Kim, Ah Young; Lee, Hyun Ju; Song, Chi Sung; Choi, Byung Ihn

    2000-01-01

    To determine the incidence of hepatic hemangiomas associated with wedge-shaped parenchymal enhancements adjacent to the tumors as seen on two-phase spiral CT images obtained during the hepatic arterial phase and to characterize the two-phase spiral CT findings of those hemangiomas. One hundred and eight consecutive hepatic hemangiomas in 63 patients who underwent two-phase spiral CT scanning during an 11-month period were included in this study. Two-phase spiral CT scans were obtained during the hepatic arterial phase (30-second delay) and portal venous phase (65-second delay) after injection of 120 mL of contrast material at a rate of 3 mL/sec. We evaluated the frequency with which wedge-shaped parenchymal enhancement was adjacent to the hemangiomas during the hepatic arterial phase and divided hemangiomas into two groups according to whether or not wedge-shaped parenchymal enhancement was noted (Group A and Group B). The presence of such enhancement in hemangiomas was correlated with tumor size and the grade of intratumoral enhancement. In 24 of 108 hemangiomas, wedge-shaped parenchymal enhancement adjacent to hepatic tumors was seen on two-phase CT images obtained during the hepatic arterial phase. Mean hemangioma size was 22mm in group A and 24mm in group B. There was no statistically significant relationship between lesion size and the presence of wedge-shaped parenchymal enhancement adjacent to a hemangioma. In 91.7% and 100% of tumors in Group A, and in 9.6% and 17.8% in Group B, hemangiomas showed more than 50% intratumoral enhancement during the arterial and portal venous phase, respectively. Wedge-shaped parenchymal enhancements peripheral to hepatic hemangiomas was more frequently found in tumors showing more than 50% intratumoral enhancement during these two phases (p less than 0.01). Wedge-shaped parenchymal enhancements is not uncommonly seen adjacent to hepatic hemangiomas on two-phase spiral CT images obtained during the hepatic arterial phase. A

  18. Polypropylene (P P) /polystyrene (P S) blends modified by radiation induced methods. I. transparency and structure morphology

    International Nuclear Information System (INIS)

    El-Nagger, A.M.; Ibrahim, M.S.; Said, H.M.; Zahran, A.H.

    2002-01-01

    The compatibility of polypropylene (P P)/polystyrene (P S) polymer blends modified through gamma radiation or accelerated electrons has been investigated. Two methods were suggested; either by exposing pp component or by exposing the melt extruded mixed polymers to both type of radiation. The modified blends were characterized by measuring the colour interceptions and observing the structure morphology by scanning electron microscope (SEM). A method was proposed depending on the measurement of the transparency (L * ) of the films of pure polymers and their blend before and after they had been modified by high-energy radiation. The transparency values were used to calculate quantitatively the percentage compatibility of pp/ps blends. The results showed that irradiation process through the two methods used in this work improved the compatibility of P P/P S blends. However, modification through exposing the mixed polymers is more effective than exposing pp component prior to melt extrusion mixing. The modification through irradiating mixed blends gamma radiation tends to yield improved modification than with E B radiation. On the other hand, the fracture surfaces of the blends examined by SEM gives further supports to the results of transparency measurements

  19. Sphingosine-1-Phosphate (S1P) Signaling in Neural Progenitors.

    Science.gov (United States)

    Callihan, Phillip; Alqinyah, Mohammed; Hooks, Shelley B

    2018-01-01

    Sphingosine-1-phosphate (S1P) and its receptors are important in nervous system development. Reliable in vitro human model systems are needed to further define specific roles for S1P signaling in neural development. We have described S1P-regulated signaling, survival, and differentiation in a human embryonic stem cell-derived neuroepithelial progenitor cell line (hNP1) that expresses functional S1P receptors. These cells can be further differentiated to a neuronal cell type and therefore represent a good model system to study the role of S1P signaling in human neural development. The following sections describe in detail the culture and differentiation of hNP1 cells and two assays to measure S1P signaling in these cells.

  20. Two-phase gas bubble-liquid boundary layer flow along vertical and inclined surfaces

    International Nuclear Information System (INIS)

    Cheung, F.B.; Epstein, M.

    1985-01-01

    The behavior of a two-phase gas bubble liquid boundary layer along vertical and inclined porous surfaces with uniform gas injection is investigated experimentally and analytically. Using argon gas and water as the working fluids, a photographical study of the two-phase boundary layer flow has been performed for various angles of inclination ranging from 45 0 to 135 0 and gas injection rates ranging from 0.01 to 0.1 m/s. An integral method has been employed to solve the system of equations governing the two-phase motion. The effects of the gas injection rate and the angle of inclination on the growth of the boundary layer have been determined

  1. Two phases of droplet evaporation during plasma arc spraying: reply to Chen's comment about the 'rocket' effect under conditions of thermal plasma spraying

    Energy Technology Data Exchange (ETDEWEB)

    Nemchinsky, V A [Key College, 225 Dania Beach Blvd, Dania Beach, FL 33040 (United States)

    2007-07-07

    The heating history of a droplet during its flight can be divided into two phases: (a) the initial phase when evaporation, although it occurs, does not change the heat balance of the droplet much (the case considered in our previous paper and (b) the final phase when the cooling due to evaporation balances the heat flux from the plasma. The later phase is considered in Chen's comment. In our reply, a very straightforward consideration demonstrates that even in the final phase of the droplet flight, the 'rocket' effect can be significant. (reply)

  2. Synchrotron 4-dimensional imaging of two-phase flow through porous media.

    Science.gov (United States)

    Kim, F H; Penumadu, D; Patel, P; Xiao, X; Garboczi, E J; Moylan, S P; Donmez, M A

    2016-01-01

    Near real-time visualization of complex two-phase flow in a porous medium was demonstrated with dynamic 4-dimensional (4D) (3D + time) imaging at the 2-BM beam line of the Advanced Photon Source (APS) at Argonne National Laboratory. Advancing fluid fronts through tortuous flow paths and their interactions with sand grains were clearly captured, and formations of air bubbles and capillary bridges were visualized. The intense X-ray photon flux of the synchrotron facility made 4D imaging possible, capturing the dynamic evolution of both solid and fluid phases. Computed Tomography (CT) scans were collected every 12 s with a pixel size of 3.25 µm. The experiment was carried out to improve understanding of the physics associated with two-phase flow. The results provide a source of validation data for numerical simulation codes such as Lattice-Boltzmann, which are used to model multi-phase flow through porous media.

  3. Equivalence of two models in single-phase multicomponent flow simulations

    KAUST Repository

    Wu, Yuanqing

    2016-02-28

    In this work, two models to simulate the single-phase multicomponent flow in reservoirs are introduced: single-phase multicomponent flow model and two-phase compositional flow model. Because the single-phase multicomponent flow is a special case of the two-phase compositional flow, the two-phase compositional flow model can also simulate the case. We compare and analyze the two models when simulating the single-phase multicomponent flow, and then demonstrate the equivalence of the two models mathematically. An experiment is also carried out to verify the equivalence of the two models.

  4. Equivalence of two models in single-phase multicomponent flow simulations

    KAUST Repository

    Wu, Yuanqing; Sun, Shuyu

    2016-01-01

    In this work, two models to simulate the single-phase multicomponent flow in reservoirs are introduced: single-phase multicomponent flow model and two-phase compositional flow model. Because the single-phase multicomponent flow is a special case of the two-phase compositional flow, the two-phase compositional flow model can also simulate the case. We compare and analyze the two models when simulating the single-phase multicomponent flow, and then demonstrate the equivalence of the two models mathematically. An experiment is also carried out to verify the equivalence of the two models.

  5. Phase characteristics of rheograms. Original classification of phase-related changes of rheos

    Directory of Open Access Journals (Sweden)

    Mikhail Y. Rudenko

    2014-05-01

    Full Text Available The phase characteristics of a rheogram are described in literature in general only. The existing theory of impedance rheography is based on an analysis of the form of rheogram envelopes, but not on the phase-related processes and their interpretation according to the applicable laws of physics. The aim of the present paper is to describe the phase-related characteristics of a rheogram of the ascending aorta. The method of the heart cycle phase analysis has been used for this purpose. By synchronizing an ECG of the aorta and a rheogram, an analysis of specific changes in the aorta blood filling in each phase is provided. As a result, the phase changes of a rheogram associated with the ECG phase structure are described and tabulated for first time. The author hereof offers his own original classification of the phase-related changes of rheograms.

  6. Characterization of horizontal air–water two-phase flow

    Energy Technology Data Exchange (ETDEWEB)

    Kong, Ran; Kim, Seungjin, E-mail: skim@psu.edu

    2017-02-15

    Highlights: • A visualization study is performed to develop flow regime map in horizontal flow. • Database in horizontal bubbly flow is extended using a local conductivity probe. • Frictional pressure drop analysis is performed in horizontal bubbly flow. • Drift flux analysis is performed in horizontal bubbly flow. - Abstract: This paper presents experimental studies performed to characterize horizontal air–water two-phase flow in a round pipe with an inner diameter of 3.81 cm. A detailed flow visualization study is performed using a high-speed video camera in a wide range of two-phase flow conditions to verify previous flow regime maps. Two-phase flows are classified into bubbly, plug, slug, stratified, stratified-wavy, and annular flow regimes. While the transition boundaries identified in the present study compare well with the existing ones (Mandhane et al., 1974) in general, some discrepancies are observed for bubbly-to-plug/slug, and plug-to-slug transition boundaries. Based on the new transition boundaries, three additional test conditions are determined in horizontal bubbly flow to extend the database by Talley et al. (2015a). Various local two-phase flow parameters including void fraction, interfacial area concentration, bubble velocity, and bubble Sauter mean diameter are obtained. The effects of increasing gas flow rate on void fraction, bubble Sauter mean diameter, and bubble velocity are discussed. Bubbles begin to coalesce near the gas–liquid layer instead of in the highly packed region when gas flow rate increases. Using all the current experimental data, two-phase frictional pressure loss analysis is performed using the Lockhart–Martinelli method. It is found that the coefficient C = 24 yields the best agreement with the data with the minimum average difference. Moreover, drift flux analysis is performed to predict void-weighted area-averaged bubble velocity and area-averaged void fraction. Based on the current database, functional

  7. The pressure effects on two-phase anaerobic digestion

    International Nuclear Information System (INIS)

    Chen, Yuling; Rößler, Benjamin; Zielonka, Simon; Lemmer, Andreas; Wonneberger, Anna-Maria; Jungbluth, Thomas

    2014-01-01

    Highlights: • The pressure effect on anaerobic digestion up to 9 bar was examined. • Increasing pressure decreased pH value in the anaerobic filter. • Increasing pressure increased methane content. • Increasing pressure decreased specific methane yield slightly. • The pressurized methane reactor was very stable and performed well. - Abstract: Two-phase pressurized anaerobic digestion is a novel process aimed at facilitating injection of the produced biogas into the natural gas grid by integrating the fermentative biogas production and upgrading it to substitute natural gas. In order to understand the mechanisms, knowledge of pressure effects on anaerobic digestion is required. To examine the effects of pressure on the anaerobic digestion process, a two-phase anaerobic digestion system was built up in laboratory scale, including three acidogenesis-leach-bed-reactors and one pressure-resistant anaerobic filter. Four different pressure levels (the absolute pressure of 1 bar, 3 bar, 6 bar and 9 bar) were applied to the methane reactor in sequence, with the organic loading rate maintained at approximately 5.1 kgCOD m −3 d −1 . Gas production, gas quality, pH value, volatile fatty acids, alcohol, ammonium-nitrogen, chemical oxygen demand (COD) and alkaline buffer capacity were analyzed. No additional caustic chemicals were added for pH adjustment throughout the experiment. With the pressure increasing from 1.07 bar to 8.91 bar, the pH value decreased from 7.2 to 6.5, the methane content increased from 66% to 75%, and the specific methane yield was slightly reduced from 0.33 l N g −1 COD to 0.31 l N g −1 COD. There was almost no acid-accumulation during the entire experiment. The average COD-degradation grade was always more than 93%, and the average alkaline buffering capacity (VFA/TIC ratio) did not exceed 0.2 at any pressure level. The anaerobic filter showed a very stable performance, regardless of the pressure variation

  8. Relative Modification of Prompt ψ(2S) and J/ψ Yields from pp to PbPb Collisions at sqrt[s_{NN}]=5.02  TeV.

    Science.gov (United States)

    Sirunyan, A M; Tumasyan, A; Adam, W; Asilar, E; Bergauer, T; Brandstetter, J; Brondolin, E; Dragicevic, M; Erö, J; Flechl, M; Friedl, M; Frühwirth, R; Ghete, V M; Hartl, C; Hörmann, N; Hrubec, J; Jeitler, M; König, A; Krätschmer, I; Liko, D; Matsushita, T; Mikulec, I; Rabady, D; Rad, N; Rahbaran, B; Rohringer, H; Schieck, J; Strauss, J; Waltenberger, W; Wulz, C-E; Chekhovsky, V; Dvornikov, O; Dydyshka, Y; Emeliantchik, I; Litomin, A; Makarenko, V; Mossolov, V; Stefanovitch, R; Suarez Gonzalez, J; Zykunov, V; Shumeiko, N; Alderweireldt, S; De Wolf, E A; Janssen, X; Lauwers, J; Van De Klundert, M; Van Haevermaet, H; Van Mechelen, P; Van Remortel, N; Van Spilbeeck, A; Abu Zeid, S; Blekman, F; D'Hondt, J; Daci, N; De Bruyn, I; Deroover, K; Lowette, S; Moortgat, S; Moreels, L; Olbrechts, A; Python, Q; Skovpen, K; Tavernier, S; Van Doninck, W; Van Mulders, P; Van Parijs, I; Brun, H; Clerbaux, B; De Lentdecker, G; Delannoy, H; Fasanella, G; Favart, L; Goldouzian, R; Grebenyuk, A; Karapostoli, G; Lenzi, T; Léonard, A; Luetic, J; Maerschalk, T; Marinov, A; Randle-Conde, A; Seva, T; Vander Velde, C; Vanlaer, P; Vannerom, D; Yonamine, R; Zenoni, F; Zhang, F; Cimmino, A; Cornelis, T; Dobur, D; Fagot, A; Garcia, G; Gul, M; Khvastunov, I; Poyraz, D; Salva, S; Schöfbeck, R; Tytgat, M; Van Driessche, W; Yazgan, E; Zaganidis, N; Bakhshiansohi, H; Beluffi, C; Bondu, O; Brochet, S; Bruno, G; Caudron, A; De Visscher, S; Delaere, C; Delcourt, M; Francois, B; Giammanco, A; Jafari, A; Jez, P; Komm, M; Krintiras, G; Lemaitre, V; Magitteri, A; Mertens, A; Musich, M; Nuttens, C; Piotrzkowski, K; Quertenmont, L; Selvaggi, M; Vidal Marono, M; Wertz, S; Beliy, N; Aldá Júnior, W L; Alves, F L; Alves, G A; Brito, L; Hensel, C; Moraes, A; Pol, M E; Rebello Teles, P; Belchior Batista Das Chagas, E; Carvalho, W; Chinellato, J; Custódio, A; Da Costa, E M; Da Silveira, G G; De Jesus Damiao, D; De Oliveira Martins, C; Fonseca De Souza, S; Huertas Guativa, L M; Malbouisson, H; Matos Figueiredo, D; Mora Herrera, C; Mundim, L; Nogima, H; Prado Da Silva, W L; Santoro, A; Sznajder, A; Tonelli Manganote, E J; Vilela Pereira, A; Ahuja, S; Bernardes, C A; Dogra, S; Tomei, T R Fernandez Perez; Gregores, E M; Mercadante, P G; Moon, C S; Novaes, S F; Padula, Sandra S; Romero Abad, D; Ruiz Vargas, J C; Aleksandrov, A; Hadjiiska, R; Iaydjiev, P; Rodozov, M; Stoykova, S; Sultanov, G; Vutova, M; Dimitrov, A; Glushkov, I; Litov, L; Pavlov, B; Petkov, P; Fang, W; Ahmad, M; Bian, J G; Chen, G M; Chen, H S; Chen, M; Chen, Y; Cheng, T; Jiang, C H; Leggat, D; Liu, Z; Romeo, F; Shaheen, S M; Spiezia, A; Tao, J; Wang, C; Wang, Z; Zhang, H; Zhao, J; Ban, Y; Chen, G; Li, Q; Liu, S; Mao, Y; Qian, S J; Wang, D; Xu, Z; Avila, C; Cabrera, A; Chaparro Sierra, L F; Florez, C; Gomez, J P; González Hernández, C F; Ruiz Alvarez, J D; Sanabria, J C; Godinovic, N; Lelas, D; Puljak, I; Ribeiro Cipriano, P M; Sculac, T; Antunovic, Z; Kovac, M; Brigljevic, V; Ferencek, D; Kadija, K; Mesic, B; Micanovic, S; Sudic, L; Susa, T; Attikis, A; Mavromanolakis, G; Mousa, J; Nicolaou, C; Ptochos, F; Razis, P A; Rykaczewski, H; Tsiakkouri, D; Finger, M; Finger, M; Carrera Jarrin, E; Ellithi Kamel, A; Mahmoud, M A; Radi, A; Kadastik, M; Perrini, L; Raidal, M; Tiko, A; Veelken, C; Eerola, P; Pekkanen, J; Voutilainen, M; Härkönen, J; Järvinen, T; Karimäki, V; Kinnunen, R; Lampén, T; Lassila-Perini, K; Lehti, S; Lindén, T; Luukka, P; Tuominiemi, J; Tuovinen, E; Wendland, L; Talvitie, J; Tuuva, T; Besancon, M; Couderc, F; Dejardin, M; Denegri, D; Fabbro, B; Faure, J L; Favaro, C; Ferri, F; Ganjour, S; Ghosh, S; Givernaud, A; Gras, P; Hamel de Monchenault, G; Jarry, P; Kucher, I; Locci, E; Machet, M; Malcles, J; Rander, J; Rosowsky, A; Titov, M; Zghiche, A; Abdulsalam, A; Antropov, I; Arleo, F; Baffioni, S; Beaudette, F; Busson, P; Cadamuro, L; Chapon, E; Charlot, C; Davignon, O; Granier de Cassagnac, R; Jo, M; Lisniak, S; Martin Blanco, J; Miné, P; Nguyen, M; Ochando, C; Ortona, G; Paganini, P; Pigard, P; Regnard, S; Salerno, R; Sirois, Y; Stahl Leiton, A G; Strebler, T; Yilmaz, Y; Zabi, A; Agram, J-L; Andrea, J; Aubin, A; Bloch, D; Brom, J-M; Buttignol, M; Chabert, E C; Chanon, N; Collard, C; Conte, E; Coubez, X; Fontaine, J-C; Gelé, D; Goerlach, U; Le Bihan, A-C; Van Hove, P; Gadrat, S; Beauceron, S; Bernet, C; Boudoul, G; Carrillo Montoya, C A; Chierici, R; Contardo, D; Courbon, B; Depasse, P; El Mamouni, H; Fan, J; Fay, J; Gascon, S; Gouzevitch, M; Grenier, G; Ille, B; Lagarde, F; Laktineh, I B; Lethuillier, M; Mirabito, L; Pequegnot, A L; Perries, S; Popov, A; Sabes, D; Sordini, V; Vander Donckt, M; Verdier, P; Viret, S; Toriashvili, T; Tsamalaidze, Z; Autermann, C; Beranek, S; Feld, L; Kiesel, M K; Klein, K; Lipinski, M; Preuten, M; Schael, S; Schomakers, C; Schulz, J; Verlage, T; Albert, A; Brodski, M; Dietz-Laursonn, E; Duchardt, D; Endres, M; Erdmann, M; Erdweg, S; Esch, T; Fischer, R; Güth, A; Hamer, M; Hebbeker, T; Heidemann, C; Hoepfner, K; Knutzen, S; Merschmeyer, M; Meyer, A; Millet, P; Mukherjee, S; Olschewski, M; Padeken, K; Pook, T; Radziej, M; Reithler, H; Rieger, M; Scheuch, F; Sonnenschein, L; Teyssier, D; Thüer, S; Cherepanov, V; Flügge, G; Kargoll, B; Kress, T; Künsken, A; Lingemann, J; Müller, T; Nehrkorn, A; Nowack, A; Pistone, C; Pooth, O; Stahl, A; Aldaya Martin, M; Arndt, T; Asawatangtrakuldee, C; Beernaert, K; Behnke, O; Behrens, U; Bin Anuar, A A; Borras, K; Campbell, A; Connor, P; Contreras-Campana, C; Costanza, F; Diez Pardos, C; Dolinska, G; Eckerlin, G; Eckstein, D; Eichhorn, T; Eren, E; Gallo, E; Garay Garcia, J; Geiser, A; Gizhko, A; Grados Luyando, J M; Grohsjean, A; Gunnellini, P; Harb, A; Hauk, J; Hempel, M; Jung, H; Kalogeropoulos, A; Karacheban, O; Kasemann, M; Keaveney, J; Kleinwort, C; Korol, I; Krücker, D; Lange, W; Lelek, A; Leonard, J; Lipka, K; Lobanov, A; Lohmann, W; Mankel, R; Melzer-Pellmann, I-A; Meyer, A B; Mittag, G; Mnich, J; Mussgiller, A; Ntomari, E; Pitzl, D; Placakyte, R; Raspereza, A; Roland, B; Sahin, M Ö; Saxena, P; Schoerner-Sadenius, T; Seitz, C; Spannagel, S; Stefaniuk, N; Van Onsem, G P; Walsh, R; Wissing, C; Blobel, V; Centis Vignali, M; Draeger, A R; Dreyer, T; Garutti, E; Gonzalez, D; Haller, J; Hoffmann, M; Junkes, A; Klanner, R; Kogler, R; Kovalchuk, N; Lapsien, T; Lenz, T; Marchesini, I; Marconi, D; Meyer, M; Niedziela, M; Nowatschin, D; Pantaleo, F; Peiffer, T; Perieanu, A; Poehlsen, J; Sander, C; Scharf, C; Schleper, P; Schmidt, A; Schumann, S; Schwandt, J; Stadie, H; Steinbrück, G; Stober, F M; Stöver, M; Tholen, H; Troendle, D; Usai, E; Vanelderen, L; Vanhoefer, A; Vormwald, B; Akbiyik, M; Barth, C; Baur, S; Baus, C; Berger, J; Butz, E; Caspart, R; Chwalek, T; Colombo, F; De Boer, W; Dierlamm, A; Fink, S; Freund, B; Friese, R; Giffels, M; Gilbert, A; Goldenzweig, P; Haitz, D; Hartmann, F; Heindl, S M; Husemann, U; Katkov, I; Kudella, S; Mildner, H; Mozer, M U; Müller, Th; Plagge, M; Quast, G; Rabbertz, K; Röcker, S; Roscher, F; Schröder, M; Shvetsov, I; Sieber, G; Simonis, H J; Ulrich, R; Wayand, S; Weber, M; Weiler, T; Williamson, S; Wöhrmann, C; Wolf, R; Anagnostou, G; Daskalakis, G; Geralis, T; Giakoumopoulou, V A; Kyriakis, A; Loukas, D; Topsis-Giotis, I; Kesisoglou, S; Panagiotou, A; Saoulidou, N; Tziaferi, E; Evangelou, I; Flouris, G; Foudas, C; Kokkas, P; Loukas, N; Manthos, N; Papadopoulos, I; Paradas, E; Filipovic, N; Bencze, G; Hajdu, C; Horvath, D; Sikler, F; Veszpremi, V; Vesztergombi, G; Zsigmond, A J; Beni, N; Czellar, S; Karancsi, J; Makovec, A; Molnar, J; Szillasi, Z; Bartók, M; Raics, P; Trocsanyi, Z L; Ujvari, B; Bahinipati, S; Choudhury, S; Mal, P; Mandal, K; Nayak, A; Sahoo, D K; Sahoo, N; Swain, S K; Bansal, S; Beri, S B; Bhatnagar, V; Chawla, R; Bhawandeep, U; Kalsi, A K; Kaur, A; Kaur, M; Kumar, R; Kumari, P; Mehta, A; Mittal, M; Singh, J B; Walia, G; Kumar, Ashok; Bhardwaj, A; Choudhary, B C; Garg, R B; Keshri, S; Malhotra, S; Naimuddin, M; Nishu, N; Ranjan, K; Sharma, R; Sharma, V; Bhattacharya, R; Bhattacharya, S; Chatterjee, K; Dey, S; Dutt, S; Dutta, S; Ghosh, S; Majumdar, N; Modak, A; Mondal, K; Mukhopadhyay, S; Nandan, S; Purohit, A; Roy, A; Roy, D; Roy Chowdhury, S; Sarkar, S; Sharan, M; Thakur, S; Behera, P K; Chudasama, R; Dutta, D; Jha, V; Kumar, V; Mohanty, A K; Netrakanti, P K; Pant, L M; Shukla, P; Topkar, A; Aziz, T; Dugad, S; Kole, G; Mahakud, B; Mitra, S; Mohanty, G B; Parida, B; Sur, N; Sutar, B; Banerjee, S; Bhowmik, S; Dewanjee, R K; Ganguly, S; Guchait, M; Jain, Sa; Kumar, S; Maity, M; Majumder, G; Mazumdar, K; Sarkar, T; Wickramage, N; Chauhan, S; Dube, S; Hegde, V; Kapoor, A; Kothekar, K; Pandey, S; Rane, A; Sharma, S; Chenarani, S; Eskandari Tadavani, E; Etesami, S M; Fahim, A; Khakzad, M; Mohammadi Najafabadi, M; Naseri, M; Paktinat Mehdiabadi, S; Rezaei Hosseinabadi, F; Safarzadeh, B; Zeinali, M; Felcini, M; Grunewald, M; Abbrescia, M; Calabria, C; Caputo, C; Colaleo, A; Creanza, D; Cristella, L; De Filippis, N; De Palma, M; Fiore, L; Iaselli, G; Maggi, G; Maggi, M; Miniello, G; My, S; Nuzzo, S; Pompili, A; Pugliese, G; Radogna, R; Ranieri, A; Selvaggi, G; Sharma, A; Silvestris, L; Venditti, R; Verwilligen, P; Abbiendi, G; Battilana, C; Bonacorsi, D; Braibant-Giacomelli, S; Brigliadori, L; Campanini, R; Capiluppi, P; Castro, A; Cavallo, F R; Chhibra, S S; Codispoti, G; Cuffiani, M; Dallavalle, G M; Fabbri, F; Fanfani, A; Fasanella, D; Giacomelli, P; Grandi, C; Guiducci, L; Marcellini, S; Masetti, G; Montanari, A; Navarria, F L; Perrotta, A; Rossi, A M; Rovelli, T; Siroli, G P; Tosi, N; Albergo, S; Costa, S; Di Mattia, A; Giordano, F; Potenza, R; Tricomi, A; Tuve, C; Barbagli, G; Ciulli, V; Civinini, C; D'Alessandro, R; Focardi, E; Lenzi, P; Meschini, M; Paoletti, S; Sguazzoni, G; Viliani, L; Benussi, L; Bianco, S; Fabbri, F; Piccolo, D; Primavera, F; Calvelli, V; Ferro, F; Lo Vetere, M; Monge, M R; Robutti, E; Tosi, S; Brianza, L; Brivio, F; Dinardo, M E; Fiorendi, S; Gennai, S; Ghezzi, A; Govoni, P; Malberti, M; Malvezzi, S; Manzoni, R A; Menasce, D; Moroni, L; Paganoni, M; Pedrini, D; Pigazzini, S; Ragazzi, S; Tabarelli de Fatis, T; Buontempo, S; Cavallo, N; De Nardo, G; Di Guida, S; Esposito, M; Fabozzi, F; Fienga, F; Iorio, A O M; Lanza, G; Lista, L; Meola, S; Paolucci, P; Sciacca, C; Thyssen, F; Azzi, P; Bacchetta, N; Benato, L; Bisello, D; Boletti, A; Carlin, R; Carvalho Antunes De Oliveira, A; Checchia, P; Dall'Osso, M; De Castro Manzano, P; Dorigo, T; Dosselli, U; Gasparini, F; Gasparini, U; Gozzelino, A; Lacaprara, S; Margoni, M; Meneguzzo, A T; Pazzini, J; Pozzobon, N; Ronchese, P; Simonetto, F; Torassa, E; Zanetti, M; Zotto, P; Zumerle, G; Braghieri, A; Magnani, A; Montagna, P; Ratti, S P; Re, V; Riccardi, C; Salvini, P; Vai, I; Vitulo, P; Alunni Solestizi, L; Bilei, G M; Ciangottini, D; Fanò, L; Lariccia, P; Leonardi, R; Mantovani, G; Menichelli, M; Saha, A; Santocchia, A; Androsov, K; Azzurri, P; Bagliesi, G; Bernardini, J; Boccali, T; Castaldi, R; Ciocci, M A; Dell'Orso, R; Donato, S; Fedi, G; Giassi, A; Grippo, M T; Ligabue, F; Lomtadze, T; Martini, L; Messineo, A; Palla, F; Rizzi, A; Savoy-Navarro, A; Spagnolo, P; Tenchini, R; Tonelli, G; Venturi, A; Verdini, P G; Barone, L; Cavallari, F; Cipriani, M; Del Re, D; Diemoz, M; Gelli, S; Longo, E; Margaroli, F; Marzocchi, B; Meridiani, P; Organtini, G; Paramatti, R; Preiato, F; Rahatlou, S; Rovelli, C; Santanastasio, F; Amapane, N; Arcidiacono, R; Argiro, S; Arneodo, M; Bartosik, N; Bellan, R; Biino, C; Cartiglia, N; Cenna, F; Costa, M; Covarelli, R; Degano, A; Demaria, N; Finco, L; Kiani, B; Mariotti, C; Maselli, S; Migliore, E; Monaco, V; Monteil, E; Monteno, M; Obertino, M M; Pacher, L; Pastrone, N; Pelliccioni, M; Pinna Angioni, G L; Ravera, F; Romero, A; Ruspa, M; Sacchi, R; Shchelina, K; Sola, V; Solano, A; Staiano, A; Traczyk, P; Belforte, S; Casarsa, M; Cossutti, F; Della Ricca, G; Zanetti, A; Kim, D H; Kim, G N; Kim, M S; Lee, S; Lee, S W; Oh, Y D; Sekmen, S; Son, D C; Yang, Y C; Lee, A; Kim, H; Brochero Cifuentes, J A; Kim, T J; Cho, S; Choi, S; Go, Y; Gyun, D; Ha, S; Hong, B; Jo, Y; Kim, Y; Lee, B; Lee, K; Lee, K S; Lee, S; Lim, J; Park, S K; Roh, Y; Almond, J; Kim, J; Lee, H; Oh, S B; Radburn-Smith, B C; Seo, S H; Yang, U K; Yoo, H D; Yu, G B; Choi, M; Kim, H; Kim, J H; Lee, J S H; Park, I C; Ryu, G; Ryu, M S; Choi, Y; Goh, J; Hwang, C; Lee, J; Yu, I; Dudenas, V; Juodagalvis, A; Vaitkus, J; Ahmed, I; Ibrahim, Z A; Komaragiri, J R; Md Ali, M A B; Mohamad Idris, F; Wan Abdullah, W A T; Yusli, M N; Zolkapli, Z; Castilla-Valdez, H; De La Cruz-Burelo, E; Heredia-De La Cruz, I; Hernandez-Almada, A; Lopez-Fernandez, R; Magaña Villalba, R; Mejia Guisao, J; Sanchez-Hernandez, A; Carrillo Moreno, S; Oropeza Barrera, C; Vazquez Valencia, F; Carpinteyro, S; Pedraza, I; Salazar Ibarguen, H A; Uribe Estrada, C; Morelos Pineda, A; Krofcheck, D; Butler, P H; Ahmad, A; Ahmad, M; Hassan, Q; Hoorani, H R; Khan, W A; Saddique, A; Shah, M A; Shoaib, M; Waqas, M; Bialkowska, H; Bluj, M; Boimska, B; Frueboes, T; Górski, M; Kazana, M; Nawrocki, K; Romanowska-Rybinska, K; Szleper, M; Zalewski, P; Bunkowski, K; Byszuk, A; Doroba, K; Kalinowski, A; Konecki, M; Krolikowski, J; Misiura, M; Olszewski, M; Walczak, M; Bargassa, P; Beirão Da Cruz E Silva, C; Calpas, B; Di Francesco, A; Faccioli, P; Ferreira Parracho, P G; Gallinaro, M; Hollar, J; Leonardo, N; Lloret Iglesias, L; Nemallapudi, M V; Rodrigues Antunes, J; Seixas, J; Toldaiev, O; Vadruccio, D; Varela, J; Vischia, P; Afanasiev, S; Bunin, P; Gavrilenko, M; Golutvin, I; Gorbunov, I; Kamenev, A; Karjavin, V; Lanev, A; Malakhov, A; Matveev, V; Palichik, V; Perelygin, V; Shmatov, S; Shulha, S; Skatchkov, N; Smirnov, V; Voytishin, N; Zarubin, A; Chtchipounov, L; Golovtsov, V; Ivanov, Y; Kim, V; Kuznetsova, E; Murzin, V; Oreshkin, V; Sulimov, V; Vorobyev, A; Andreev, Yu; Dermenev, A; Gninenko, S; Golubev, N; Karneyeu, A; Kirsanov, M; Krasnikov, N; Pashenkov, A; Tlisov, D; Toropin, A; Epshteyn, V; Gavrilov, V; Lychkovskaya, N; Popov, V; Pozdnyakov, I; Safronov, G; Spiridonov, A; Toms, M; Vlasov, E; Zhokin, A; Bylinkin, A; Chistov, R; Markin, O; Polikarpov, S; Andreev, V; Azarkin, M; Dremin, I; Kirakosyan, M; Leonidov, A; Terkulov, A; Baskakov, A; Belyaev, A; Boos, E; Ershov, A; Gribushin, A; Kaminskiy, A; Kodolova, O; Korotkikh, V; Lokhtin, I; Miagkov, I; Obraztsov, S; Petrushanko, S; Savrin, V; Snigirev, A; Vardanyan, I; Blinov, V; Skovpen, Y; Shtol, D; Azhgirey, I; Bayshev, I; Bitioukov, S; Elumakhov, D; Kachanov, V; Kalinin, A; Konstantinov, D; Krychkine, V; Petrov, V; Ryutin, R; Sobol, A; Troshin, S; Tyurin, N; Uzunian, A; Volkov, A; Adzic, P; Cirkovic, P; Devetak, D; Dordevic, M; Milosevic, J; Rekovic, V; Alcaraz Maestre, J; Barrio Luna, M; Calvo, E; Cerrada, M; Chamizo Llatas, M; Colino, N; De La Cruz, B; Delgado Peris, A; Escalante Del Valle, A; Fernandez Bedoya, C; Fernández Ramos, J P; Flix, J; Fouz, M C; Garcia-Abia, P; Gonzalez Lopez, O; Goy Lopez, S; Hernandez, J M; Josa, M I; Navarro De Martino, E; Pérez-Calero Yzquierdo, A; Puerta Pelayo, J; Quintario Olmeda, A; Redondo, I; Romero, L; Soares, M S; de Trocóniz, J F; Missiroli, M; Moran, D; Cuevas, J; Fernandez Menendez, J; Gonzalez Caballero, I; González Fernández, J R; Palencia Cortezon, E; Sanchez Cruz, S; Suárez Andrés, I; Vizan Garcia, J M; Cabrillo, I J; Calderon, A; Castiñeiras De Saa, J R; Curras, E; Fernandez, M; Garcia-Ferrero, J; Gomez, G; Lopez Virto, A; Marco, J; Martinez Rivero, C; Matorras, F; Piedra Gomez, J; Rodrigo, T; Ruiz-Jimeno, A; Scodellaro, L; Trevisani, N; Vila, I; Vilar Cortabitarte, R; Abbaneo, D; Auffray, E; Auzinger, G; Bachtis, M; Baillon, P; Ball, A H; Barney, D; Bloch, P; Bocci, A; Bonato, A; Botta, C; Camporesi, T; Castello, R; Cepeda, M; Cerminara, G; d'Enterria, D; Dabrowski, A; Daponte, V; David, A; De Gruttola, M; De Roeck, A; Di Marco, E; Dobson, M; Dorney, B; du Pree, T; Duggan, D; Dünser, M; Dupont, N; Elliott-Peisert, A; Everaerts, P; Fartoukh, S; Franzoni, G; Fulcher, J; Funk, W; Gigi, D; Gill, K; Girone, M; Glege, F; Gulhan, D; Gundacker, S; Guthoff, M; Hammer, J; Harris, P; Hegeman, J; Innocente, V; Janot, P; Kieseler, J; Kirschenmann, H; Knünz, V; Kornmayer, A; Kortelainen, M J; Kousouris, K; Krammer, M; Lange, C; Lecoq, P; Lourenço, C; Lucchini, M T; Malgeri, L; Mannelli, M; Martelli, A; Meijers, F; Merlin, J A; Mersi, S; Meschi, E; Milenovic, P; Moortgat, F; Morovic, S; Mulders, M; Neugebauer, H; Orfanelli, S; Orsini, L; Pape, L; Perez, E; Peruzzi, M; Petrilli, A; Petrucciani, G; Pfeiffer, A; Pierini, M; Racz, A; Reis, T; Rolandi, G; Rovere, M; Ruan, M; Sakulin, H; Sauvan, J B; Schäfer, C; Schwick, C; Seidel, M; Sharma, A; Silva, P; Sphicas, P; Steggemann, J; Stoye, M; Takahashi, Y; Tosi, M; Treille, D; Triossi, A; Tsirou, A; Veckalns, V; Veres, G I; Verweij, M; Wardle, N; Wöhri, H K; Zagozdzinska, A; Zeuner, W D; Bertl, W; Deiters, K; Erdmann, W; Horisberger, R; Ingram, Q; Kaestli, H C; Kotlinski, D; Langenegger, U; Rohe, T; Bachmair, F; Bäni, L; Bianchini, L; Casal, B; Dissertori, G; Dittmar, M; Donegà, M; Grab, C; Heidegger, C; Hits, D; Hoss, J; Kasieczka, G; Lecomte, P; Lustermann, W; Mangano, B; Marionneau, M; Martinez Ruiz Del Arbol, P; Masciovecchio, M; Meinhard, M T; Meister, D; Micheli, F; Musella, P; Nessi-Tedaldi, F; Pandolfi, F; Pata, J; Pauss, F; Perrin, G; Perrozzi, L; Quittnat, M; Rossini, M; Schönenberger, M; Starodumov, A; Tavolaro, V R; Theofilatos, K; Wallny, R; Aarrestad, T K; Amsler, C; Caminada, L; Canelli, M F; De Cosa, A; Galloni, C; Hinzmann, A; Hreus, T; Kilminster, B; Ngadiuba, J; Pinna, D; Rauco, G; Robmann, P; Salerno, D; Yang, Y; Zucchetta, A; Candelise, V; Doan, T H; Jain, Sh; Khurana, R; Konyushikhin, M; Kuo, C M; Lin, W; Lu, Y J; Pozdnyakov, A; Yu, S S; Kumar, Arun; Chang, P; Chang, Y H; Chang, Y W; Chao, Y; Chen, K F; Chen, P H; Dietz, C; Fiori, F; Hou, W-S; Hsiung, Y; Liu, Y F; Lu, R-S; Miñano Moya, M; Paganis, E; Psallidas, A; Tsai, J F; Tzeng, Y M; Asavapibhop, B; Singh, G; Srimanobhas, N; Suwonjandee, N; Adiguzel, A; Cerci, S; Damarseckin, S; Demiroglu, Z S; Dozen, C; Dumanoglu, I; Girgis, S; Gokbulut, G; Guler, Y; Hos, I; Kangal, E E; Kara, O; Kayis Topaksu, A; Kiminsu, U; Oglakci, M; Onengut, G; Ozdemir, K; Sunar Cerci, D; Tali, B; Turkcapar, S; Zorbakir, I S; Zorbilmez, C; Bilin, B; Bilmis, S; Isildak, B; Karapinar, G; Yalvac, M; Zeyrek, M; Gülmez, E; Kaya, M; Kaya, O; Yetkin, E A; Yetkin, T; Cakir, A; Cankocak, K; Sen, S; Grynyov, B; Levchuk, L; Sorokin, P; Aggleton, R; Ball, F; Beck, L; Brooke, J J; Burns, D; Clement, E; Cussans, D; Flacher, H; Goldstein, J; Grimes, M; Heath, G P; Heath, H F; Jacob, J; Kreczko, L; Lucas, C; Newbold, D M; Paramesvaran, S; Poll, A; Sakuma, T; Seif El Nasr-Storey, S; Smith, D; Smith, V J; Belyaev, A; Brew, C; Brown, R M; Calligaris, L; Cieri, D; Cockerill, D J A; Coughlan, J A; Harder, K; Harper, S; Olaiya, E; Petyt, D; Shepherd-Themistocleous, C H; Thea, A; Tomalin, I R; Williams, T; Baber, M; Bainbridge, R; Buchmuller, O; Bundock, A; Burton, D; Casasso, S; Citron, M; Colling, D; Corpe, L; Dauncey, P; Davies, G; De Wit, A; Della Negra, M; Di Maria, R; Dunne, P; Elwood, A; Futyan, D; Haddad, Y; Hall, G; Iles, G; James, T; Lane, R; Laner, C; Lucas, R; Lyons, L; Magnan, A-M; Malik, S; Mastrolorenzo, L; Nash, J; Nikitenko, A; Pela, J; Penning, B; Pesaresi, M; Raymond, D M; Richards, A; Rose, A; Seez, C; Summers, S; Tapper, A; Uchida, K; Vazquez Acosta, M; Virdee, T; Wright, J; Zenz, S C; Cole, J E; Hobson, P R; Khan, A; Kyberd, P; Leslie, D; Reid, I D; Symonds, P; Teodorescu, L; Turner, M; Borzou, A; Call, K; Dittmann, J; Hatakeyama, K; Liu, H; Pastika, N; Cooper, S I; Henderson, C; Rumerio, P; West, C; Arcaro, D; Avetisyan, A; Bose, T; Gastler, D; Rankin, D; Richardson, C; Rohlf, J; Sulak, L; Zou, D; Benelli, G; Berry, E; Cutts, D; Garabedian, A; Hakala, J; Heintz, U; Hogan, J M; Jesus, O; Kwok, K H M; Laird, E; Landsberg, G; Mao, Z; Narain, M; Piperov, S; Sagir, S; Spencer, E; Syarif, R; Breedon, R; Breto, G; Burns, D; Calderon De La Barca Sanchez, M; Chauhan, S; Chertok, M; Conway, J; Conway, R; Cox, P T; Erbacher, R; Flores, C; Funk, G; Gardner, M; Ko, W; Lander, R; Mclean, C; Mulhearn, M; Pellett, D; Pilot, J; Shalhout, S; Smith, J; Squires, M; Stolp, D; Tripathi, M; Bravo, C; Cousins, R; Dasgupta, A; Florent, A; Hauser, J; Ignatenko, M; Mccoll, N; Saltzberg, D; Schnaible, C; Takasugi, E; Valuev, V; Weber, M; Bouvier, E; Burt, K; Clare, R; Ellison, J; Gary, J W; Ghiasi Shirazi, S M A; Hanson, G; Heilman, J; Jandir, P; Kennedy, E; Lacroix, F; Long, O R; Olmedo Negrete, M; Paneva, M I; Shrinivas, A; Si, W; Wei, H; Wimpenny, S; Yates, B R; Branson, J G; Cerati, G B; Cittolin, S; Derdzinski, M; Gerosa, R; Holzner, A; Klein, D; Krutelyov, V; Letts, J; Macneill, I; Olivito, D; Padhi, S; Pieri, M; Sani, M; Sharma, V; Simon, S; Tadel, M; Vartak, A; Wasserbaech, S; Welke, C; Wood, J; Würthwein, F; Yagil, A; Zevi Della Porta, G; Amin, N; Bhandari, R; Bradmiller-Feld, J; Campagnari, C; Dishaw, A; Dutta, V; Franco Sevilla, M; George, C; Golf, F; Gouskos, L; Gran, J; Heller, R; Incandela, J; Mullin, S D; Ovcharova, A; Qu, H; Richman, J; Stuart, D; Suarez, I; Yoo, J; Anderson, D; Bendavid, J; Bornheim, A; Bunn, J; Chen, Y; Duarte, J; Lawhorn, J M; Mott, A; Newman, H B; Pena, C; Spiropulu, M; Vlimant, J R; Xie, S; Zhu, R Y; Andrews, M B; Ferguson, T; Paulini, M; Russ, J; Sun, M; Vogel, H; Vorobiev, I; Weinberg, M; Cumalat, J P; Ford, W T; Jensen, F; Johnson, A; Krohn, M; Mulholland, T; Stenson, K; Wagner, S R; Alexander, J; Chaves, J; Chu, J; Dittmer, S; Mcdermott, K; Mirman, N; Nicolas Kaufman, G; Patterson, J R; Rinkevicius, A; Ryd, A; Skinnari, L; Soffi, L; Tan, S M; Tao, Z; Thom, J; Tucker, J; Wittich, P; Zientek, M; Winn, D; Abdullin, S; Albrow, M; Apollinari, G; Apresyan, A; Banerjee, S; Bauerdick, L A T; Beretvas, A; Berryhill, J; Bhat, P C; Bolla, G; Burkett, K; Butler, J N; Cheung, H W K; Chlebana, F; Cihangir, S; Cremonesi, M; Elvira, V D; Fisk, I; Freeman, J; Gottschalk, E; Gray, L; Green, D; Grünendahl, S; Gutsche, O; Hare, D; Harris, R M; Hasegawa, S; Hirschauer, J; Hu, Z; Jayatilaka, B; Jindariani, S; Johnson, M; Joshi, U; Klima, B; Kreis, B; Lammel, S; Linacre, J; Lincoln, D; Lipton, R; Liu, M; Liu, T; Lopes De Sá, R; Lykken, J; Maeshima, K; Magini, N; Marraffino, J M; Maruyama, S; Mason, D; McBride, P; Merkel, P; Mrenna, S; Nahn, S; O'Dell, V; Pedro, K; Prokofyev, O; Rakness, G; Ristori, L; Sexton-Kennedy, E; Soha, A; Spalding, W J; Spiegel, L; Stoynev, S; Strait, J; Strobbe, N; Taylor, L; Tkaczyk, S; Tran, N V; Uplegger, L; Vaandering, E W; Vernieri, C; Verzocchi, M; Vidal, R; Wang, M; Weber, H A; Whitbeck, A; Wu, Y; Acosta, D; Avery, P; Bortignon, P; Bourilkov, D; Brinkerhoff, A; Carnes, A; Carver, M; Curry, D; Das, S; Field, R D; Furic, I K; Konigsberg, J; Korytov, A; Low, J F; Ma, P; Matchev, K; Mei, H; Mitselmakher, G; Rank, D; Shchutska, L; Sperka, D; Thomas, L; Wang, J; Wang, S; Yelton, J; Linn, S; Markowitz, P; Martinez, G; Rodriguez, J L; Ackert, A; Adams, J R; Adams, T; Askew, A; Bein, S; Diamond, B; Hagopian, S; Hagopian, V; Johnson, K F; Prosper, H; Santra, A; Yohay, R; Baarmand, M M; Bhopatkar, V; Colafranceschi, S; Hohlmann, M; Noonan, D; Roy, T; Yumiceva, F; Adams, M R; Apanasevich, L; Berry, D; Betts, R R; Bucinskaite, I; Cavanaugh, R; Evdokimov, O; Gauthier, L; Gerber, C E; Hofman, D J; Jung, K; Kurt, P; O'Brien, C; Sandoval Gonzalez, I D; Turner, P; Varelas, N; Wang, H; Wu, Z; Zakaria, M; Zhang, J; Bilki, B; Clarida, W; Dilsiz, K; Durgut, S; Gandrajula, R P; Haytmyradov, M; Khristenko, V; Merlo, J-P; Mermerkaya, H; Mestvirishvili, A; Moeller, A; Nachtman, J; Ogul, H; Onel, Y; Ozok, F; Penzo, A; Snyder, C; Tiras, E; Wetzel, J; Yi, K; Anderson, I; Blumenfeld, B; Cocoros, A; Eminizer, N; Fehling, D; Feng, L; Gritsan, A V; Maksimovic, P; Martin, C; Osherson, M; Roskes, J; Sarica, U; Swartz, M; Xiao, M; Xin, Y; You, C; Al-Bataineh, A; Baringer, P; Bean, A; Boren, S; Bowen, J; Bruner, C; Castle, J; Forthomme, L; Kenny, R P; Khalil, S; Kropivnitskaya, A; Majumder, D; Mcbrayer, W; Murray, M; Sanders, S; Stringer, R; Tapia Takaki, J D; Wang, Q; Ivanov, A; Kaadze, K; Maravin, Y; Mohammadi, A; Saini, L K; Skhirtladze, N; Toda, S; Rebassoo, F; Wright, D; Anelli, C; Baden, A; Baron, O; Belloni, A; Calvert, B; Eno, S C; Ferraioli, C; Gomez, J A; Hadley, N J; Jabeen, S; Kellogg, R G; Kolberg, T; Kunkle, J; Lu, Y; Mignerey, A C; Ricci-Tam, F; Shin, Y H; Skuja, A; Tonjes, M B; Tonwar, S C; Abercrombie, D; Allen, B; Apyan, A; Azzolini, V; Barbieri, R; Baty, A; Bi, R; Bierwagen, K; Brandt, S; Busza, W; Cali, I A; D'Alfonso, M; Demiragli, Z; Di Matteo, L; Gomez Ceballos, G; Goncharov, M; Hsu, D; Iiyama, Y; Innocenti, G M; Klute, M; Kovalskyi, D; Krajczar, K; Lai, Y S; Lee, Y-J; Levin, A; Luckey, P D; Maier, B; Marini, A C; Mcginn, C; Mironov, C; Narayanan, S; Niu, X; Paus, C; Roland, C; Roland, G; Salfeld-Nebgen, J; Stephans, G S F; Tatar, K; Varma, M; Velicanu, D; Veverka, J; Wang, J; Wang, T W; Wyslouch, B; Yang, M; Zhukova, V; Benvenuti, A C; Chatterjee, R M; Evans, A; Finkel, A; Gude, A; Hansen, P; Kalafut, S; Kao, S C; Kubota, Y; Lesko, Z; Mans, J; Nourbakhsh, S; Ruckstuhl, N; Rusack, R; Tambe, N; Turkewitz, J; Acosta, J G; Oliveros, S; Avdeeva, E; Bartek, R; Bloom, K; Claes, D R; Dominguez, A; Fangmeier, C; Gonzalez Suarez, R; Kamalieddin, R; Kravchenko, I; Malta Rodrigues, A; Meier, F; Monroy, J; Siado, J E; Snow, G R; Stieger, B; Alyari, M; Dolen, J; George, J; Godshalk, A; Harrington, C; Iashvili, I; Kaisen, J; Kharchilava, A; Kumar, A; Parker, A; Rappoccio, S; Roozbahani, B; Alverson, G; Barberis, E; Hortiangtham, A; Massironi, A; Morse, D M; Nash, D; Orimoto, T; Teixeira De Lima, R; Trocino, D; Wang, R-J; Wood, D; Bhattacharya, S; Charaf, O; Hahn, K A; Kubik, A; Kumar, A; Mucia, N; Odell, N; Pollack, B; Schmitt, M H; Sung, K; Trovato, M; Velasco, M; Dev, N; Hildreth, M; Hurtado Anampa, K; Jessop, C; Karmgard, D J; Kellams, N; Lannon, K; Marinelli, N; Meng, F; Mueller, C; Musienko, Y; Planer, M; Reinsvold, A; Ruchti, R; Smith, G; Taroni, S; Wayne, M; Wolf, M; Woodard, A; Alimena, J; Antonelli, L; Bylsma, B; Durkin, L S; Flowers, S; Francis, B; Hart, A; Hill, C; Hughes, R; Ji, W; Liu, B; Luo, W; Puigh, D; Winer, B L; Wulsin, H W; Cooperstein, S; Driga, O; Elmer, P; Hardenbrook, J; Hebda, P; Lange, D; Luo, J; Marlow, D; Medvedeva, T; Mei, K; Mooney, M; Olsen, J; Palmer, C; Piroué, P; Stickland, D; Svyatkovskiy, A; Tully, C; Zuranski, A; Malik, S; Barker, A; Barnes, V E; Folgueras, S; Gutay, L; Jha, M K; Jones, M; Jung, A W; Khatiwada, A; Miller, D H; Neumeister, N; Schulte, J F; Shi, X; Sun, J; Wang, F; Xie, W; Parashar, N; Stupak, J; Adair, A; Akgun, B; Chen, Z; Ecklund, K M; Geurts, F J M; Guilbaud, M; Li, W; Michlin, B; Northup, M; Padley, B P; Redjimi, R; Roberts, J; Rorie, J; Tu, Z; Zabel, J; Betchart, B; Bodek, A; de Barbaro, P; Demina, R; Duh, Y T; Ferbel, T; Galanti, M; Garcia-Bellido, A; Han, J; Hindrichs, O; Khukhunaishvili, A; Lo, K H; Tan, P; Verzetti, M; Agapitos, A; Chou, J P; Contreras-Campana, E; Gershtein, Y; Gómez Espinosa, T A; Halkiadakis, E; Heindl, M; Hidas, D; Hughes, E; Kaplan, S; Kunnawalkam Elayavalli, R; Kyriacou, S; Lath, A; Nash, K; Saka, H; Salur, S; Schnetzer, S; Sheffield, D; Somalwar, S; Stone, R; Thomas, S; Thomassen, P; Walker, M; Delannoy, A G; Foerster, M; Heideman, J; Riley, G; Rose, K; Spanier, S; Thapa, K; Bouhali, O; Celik, A; Dalchenko, M; De Mattia, M; Delgado, A; Dildick, S; Eusebi, R; Gilmore, J; Huang, T; Juska, E; Kamon, T; Mueller, R; Pakhotin, Y; Patel, R; Perloff, A; Perniè, L; Rathjens, D; Rose, A; Safonov, A; Tatarinov, A; Ulmer, K A; Akchurin, N; Cowden, C; Damgov, J; De Guio, F; Dragoiu, C; Dudero, P R; Faulkner, J; Gurpinar, E; Kunori, S; Lamichhane, K; Lee, S W; Libeiro, T; Peltola, T; Undleeb, S; Volobouev, I; Wang, Z; Greene, S; Gurrola, A; Janjam, R; Johns, W; Maguire, C; Melo, A; Ni, H; Sheldon, P; Tuo, S; Velkovska, J; Xu, Q; Arenton, M W; Barria, P; Cox, B; Goodell, J; Hirosky, R; Ledovskoy, A; Li, H; Neu, C; Sinthuprasith, T; Sun, X; Wang, Y; Wolfe, E; Xia, F; Clarke, C; Harr, R; Karchin, P E; Sturdy, J; Belknap, D A; Buchanan, J; Caillol, C; Dasu, S; Dodd, L; Duric, S; Gomber, B; Grothe, M; Herndon, M; Hervé, A; Klabbers, P; Lanaro, A; Levine, A; Long, K; Loveless, R; Ojalvo, I; Perry, T; Pierro, G A; Polese, G; Ruggles, T; Savin, A; Smith, N; Smith, W H; Taylor, D; Woods, N

    2017-04-21

    The relative modification of the prompt ψ(2S) and J/ψ yields from pp to PbPb collisions, at the center-of-mass energy of 5.02 TeV per nucleon pair, is presented. The analysis is based on pp and PbPb data samples collected by the CMS experiment at the LHC in 2015, corresponding to integrated luminosities of 28.0  pb^{-1} and 464  μb^{-1}, respectively. The double ratio of measured yields of prompt charmonia reconstructed through their decays into muon pairs, (N_{ψ(2S)}/N_{J/ψ})_{PbPb}/(N_{ψ(2S)}/N_{J/ψ})_{pp}, is determined as a function of PbPb collision centrality and charmonium transverse momentum p_{T}, in two kinematic intervals: |y|<1.6 covering 6.5<p_{T}<30  GeV/c and 1.6<|y|<2.4 covering 3<p_{T}<30  GeV/c. The centrality-integrated double ratios are 0.36±0.08(stat)±0.05(syst) in the first interval and 0.24±0.22(stat)±0.09(syst) in the second. The double ratio is lower than unity in all the measured bins, suggesting that the ψ(2S) yield is more suppressed than the J/ψ yield in the explored phase space.

  9. Analysis of π-p → π-p, π-p → π-π0p et π-p → π+π-n reactions at 2,77 GeV/c and study of the ππ elastic scattering by the Chew-Low extrapolation method applied to π-p → π-π0p and π-p → π+π-n reactions

    International Nuclear Information System (INIS)

    Laurens, Georges

    1971-01-01

    180000 pictures taken in the 2 m CERN hydrogen bubble chamber with an incident beam of 2.77 GeV/e were examined. High statistics obtained in the whole angular production range allowed to study the dσ/dt differential cross section behaviour, the mass and width of the ρ meson, and the multipole parameters of this resonance. Nevertheless, the aim of this experiment was the application of the CHEW - LOW extrapolation method. Different types of extrapolation procedures were compared. Phase shift analysis of the elastic ππ scattering between 500 and 1100 MeV, performed with conformal mappings, allowed to determine the values of the S 0 , S 2 , P 1 , D 0 , D 2 waves. Forward dispersion relations were used to obtain scattering length values of the S 2 and P 1 phase shifts. (author) [fr

  10. A Dual-Stage Two-Phase Model of Selective Attention

    Science.gov (United States)

    Hubner, Ronald; Steinhauser, Marco; Lehle, Carola

    2010-01-01

    The dual-stage two-phase (DSTP) model is introduced as a formal and general model of selective attention that includes both an early and a late stage of stimulus selection. Whereas at the early stage information is selected by perceptual filters whose selectivity is relatively limited, at the late stage stimuli are selected more efficiently on a…

  11. Two-phase-flow models and their limitations

    International Nuclear Information System (INIS)

    Ishii, M.; Kocamustafaogullari, G.

    1982-01-01

    An accurate prediction of transient two-phase flow is essential to safety analyses of nuclear reactors under accident conditions. The fluid flow and heat transfer encountered are often extremely complex due to the reactor geometry and occurrence of transient two-phase flow. Recently considerable progresses in understanding and predicting these phenomena have been made by a combination of rigorous model development, advanced computational techniques, and a number of small and large scale supporting experiments. In view of their essential importance, the foundation of various two-phase-flow models and their limitations are discussed in this paper

  12. RAC1 P29S regulates PD-L1 expression in melanoma

    Science.gov (United States)

    Vu, Ha Linh; Rosenbaum, Sheera; Purwin, Timothy J.; Davies, Michael A.; Aplin, Andrew E.

    2015-01-01

    Summary Whole exome sequencing of cutaneous melanoma has led to the detection of P29 mutations in RAC1 in 5–9% of samples, but the role of RAC1 P29 mutations in melanoma biology remains unclear. Using reverse phase protein array analysis to examine the changes in protein/phospho-protein expression, we identified cyclin B1, PD-L1, Ets-1, and Syk as being selectively upregulated with RAC1 P29S expression and downregulated with RAC1 P29S depletion. Using the melanoma patient samples in TCGA, we found PD-L1 expression to be significantly increased in RAC1 P29S patients compared to RAC1 WT as well as other RAC1 mutants. The finding that PD-L1 is upregulated suggests that oncogenic RAC1 P29S may promote suppression of the antitumor immune response. This is a new insight into the biological function of RAC1 P29S mutations with potential clinical implications as PD-L1 is a candidate biomarker for increased benefit from treatment with anti-PD1 or anti-PD-L1 antibodies. PMID:26176707

  13. A single-reciprocating-piston two-phase thermofluidic prime-mover

    International Nuclear Information System (INIS)

    Taleb, Aly I.; Timmer, Michael A.G.; El-Shazly, Mohamed Y.; Samoilov, Aleksandr; Kirillov, Valeriy A.; Markides, Christos N.

    2016-01-01

    We explore theoretically a thermodynamic heat-engine concept that has the potential of attaining a high efficiency and power density relative to competing solutions, while having a simple construction with few moving parts and dynamic seals, allowing low capital and operating costs, and long lifetimes. Specifically, an unsteady heat-engine device within which a working fluid undergoes a power cycle featuring phase-change, termed the ‘Evaporative Reciprocating-Piston Engine’ (EPRE) is considered as a potential prime mover for use in combined heat and power (CHP) applications. Based on thermal/fluid-electrical analogies, a theoretical ERPE device is conceptualized initially in the electrical-analogy domain as a linearized, closed-loop active electronic circuit model. The circuit-model representation is designed to potentially exhibit high efficiencies compared to similar, existing two-phase unsteady heat engines. From the simplified circuit model in the electrical domain, and using the thermal/fluid-electrical analogies, one possible configuration of a corresponding physical ERPE device is derived, based on an early prototype of a device currently under development that exhibits some similarities with the ERPE, and used as a physical manifestation of the proposed concept. The corresponding physical ERPE device relies on the alternating phase change of a suitable working-fluid (here, water) to drive a reciprocating displacement of a single vertical piston and to produce sustained oscillations of thermodynamic properties within an enclosed space. Four performance indicators are considered: the operational frequency, the power output, the exergy efficiency, and the heat input/temperature difference imposed externally on the device's heat exchangers that is necessary to sustain oscillations. The effects of liquid inertia, viscous drag, hydrostatic pressure, vapour compressibility and two-phase heat transfer in the various engine components/compartments are

  14. Differentiation of surface properties of chlorococcalean algae by means of aqueous two phase systems

    Directory of Open Access Journals (Sweden)

    Jan Burczyk

    2014-01-01

    Full Text Available Algal cells belonging to various strains of Chlorococcales (Chlorophyta have been partitioned in aqueous two-phase systems containing ionogenic polymers, DEAE-dextran or SDS-dextran, at various pH values. Strain-specific differences of partition type which have been found in the phase systems used can be useful for distinguishing of algal cells.

  15. Inhibition of Rac1 activity induces G1/S phase arrest through the GSK3/cyclin D1 pathway in human cancer cells.

    Science.gov (United States)

    Liu, Linna; Zhang, Hongmei; Shi, Lei; Zhang, Wenjuan; Yuan, Juanli; Chen, Xiang; Liu, Juanjuan; Zhang, Yan; Wang, Zhipeng

    2014-10-01

    Rac1 has been shown to regulate the cell cycle in cancer cells. Yet, the related mechanism remains unclear. Thus, the present study aimed to investigate the mechanism involved in the regulation of G1/S phase transition by Rac1 in cancer cells. Inhibition of Rac1 by inhibitor NSC23766 induced G1/S phase arrest and inhibited the proliferation of A431, SW480 and U2-OS cells. Suppression of GSK3 by shRNA partially rescued G1/S phase arrest and inhibition of proliferation. Incubation of cells with NSC23766 reduced p-AKT and inactivated p-GSK3α and p-GSK3β, increased p-cyclin D1 expression and decreased the level of cyclin D1 protein. Consequently, cyclin D1 targeting transcriptional factor E2F1 expression, which promotes G1 to S phase transition, was also reduced. In contrast, constitutive active Rac1 resulted in increased p-AKT and inactivated p-GSK3α and p-GSK3β, decreased p-cyclin D1 expression and enhanced levels of cyclin D1 and E2F1 expression. Moreover, suppression of GSK3 did not alter p-AKT or Rac1 activity, but decreased p-cyclin D1 and increased total cyclin D1 protein. However, neither Rac1 nor GSK3 inhibition altered cyclin D1 at the RNA level. Moreover, after inhibition of Rac1 or GSK3 following proteasome inhibitor MG132 treatment, cyclin D1 expression at the protein level remained constant, indicating that Rac1 and GSK3 may regulate cyclin D1 turnover through phosphorylation and degradation. Therefore, our findings suggest that inhibition of Rac1 induces cell cycle G1/S arrest in cancer cells by regulation of the GSK3/cyclin D1 pathway.

  16. Simulation experiments for hot-leg U-bend two-phase flow phenomena

    International Nuclear Information System (INIS)

    Ishii, M.; Hsu, J.T.; Tucholke, D.; Lambert, G.; Kataoka, I.

    1986-01-01

    In order to study the two-phase natural circulation and flow termination during a small break loss of coolant accident in LWR, simulation experiments have been performed. Based on the two-phase flow scaling criteria developed under this program, an adiabatic hot leg U-bend simulation loop using nitrogen gas and water and a Freon 113 boiling and condensation loop were built. The nitrogen-water system has been used to isolate key hydrodynamic phenomena from heat transfer problems, whereas the Freon loop has been used to study the effect of phase changes and fluid properties. Various tests were carried out to establish the basic mechanism of the flow termination and reestablishment as well as to obtain essential information on scale effects of parameters such as the loop frictional resistance, thermal center, U-bend curvature and inlet geometry. In addition to the above experimental study, a preliminary modeling study has been carried out for two-phase flow in a large vertical pipe at relatively low gas fluxes typical of natural circulation conditions

  17. Hypersensitivity of mouse NEIL1-knockdown cells to hydrogen peroxide during S phase

    International Nuclear Information System (INIS)

    Yamamoto, Ryohei; Ohshiro, Yukari; Shimotani, Tatsuhiko; Yamamoto, Mizuki; Matsuyama, Satoshi; Ide, Hiroshi; Kubo, Kihei

    2014-01-01

    Oxidative base damage occurs spontaneously due to reactive oxygen species generated as byproducts of respiration and other pathological processes in mammalian cells. Many oxidized bases are mutagenic and/or toxic, and most are repaired through the base excision repair pathway. Human endonuclease VIII-like protein 1 (hNEIL1) is thought to play an important role during the S phase of the cell cycle by removing oxidized bases in DNA replication fork-like (bubble) structures, and the protein level of hNEIL1 is increased in S phase. Compared with hNEIL1, there is relatively little information on the properties of the mouse ortholog mNEIL1. Since mouse cell nuclei lack endonuclease III-like protein (NTH) activity, in contrast to human cell nuclei, mNEIL1 is a major DNA glycosylase for repair of oxidized pyrimidines in mouse nuclei. In this study, we made mNEIL1-knockdown cells using an shRNA expression vector and examined the cell cycle-related variation in hydrogen peroxide (H 2 O 2 ) sensitivity. Hypersensitivity to H 2 O 2 caused by mNEIL1 knockdown was more significant in S phase than in G1 phase, suggesting that mNEIL1 has an important role during S phase, similarly to hNEIL1

  18. Eulerian-Eulerian two-phase numerical simulation of nanofluid laminar forced convection in a microchannel

    International Nuclear Information System (INIS)

    Kalteh, Mohammad; Abbassi, Abbas; Saffar-Avval, Majid; Harting, Jens

    2011-01-01

    In this paper, laminar forced convection heat transfer of a copper-water nanofluid inside an isothermally heated microchannel is studied numerically. An Eulerian two-fluid model is considered to simulate the nanofluid flow inside the microchannel and the governing mass, momentum and energy equations for both phases are solved using the finite volume method. For the first time, the detailed study of the relative velocity and temperature of the phases are presented and it has been observed that the relative velocity and temperature between the phases is very small and negligible and the nanoparticle concentration distribution is uniform. However, the two-phase modeling results show higher heat transfer enhancement in comparison to the homogeneous single-phase model. Also, the heat transfer enhancement increases with increase in Reynolds number and nanoparticle volume concentration as well as with decrease in the nanoparticle diameter, while the pressure drop increases only slightly.

  19. Numerical calculation of two-phase turbulent jets

    Energy Technology Data Exchange (ETDEWEB)

    Saif, A.A.

    1995-05-01

    Two-phase turbulent round jets were numerically simulated using a multidimensional two-phase CFD code based on the two-fluid model. The turbulence phenomena were treated with the standard k-{epsilon} model. It was modified to take into account the additional dissipation of turbulent kinetic energy by the dispersed phase. Within the context of the two-fluid model it is more appropriate and physically justified to treat the diffusion by an interfacial force in the momentum equation. In this work, the diffusion force and the additional dissipation effect by the dispersed phase were modeled starting from the classical turbulent energy spectrum analysis. A cut-off frequency was proposed to decrease the dissipation effect by the dispersed phase when large size particles are introduced in the flow. The cut-off frequency combined with the bubble-induced turbulence effect allows for an increase in turbulence for large particles. Additional care was taken in choosing the right kind of experimental data from the literature so that a good separate effect test was possible for their models. The models predicted the experimental data very closely and they were general enough to predict extreme limit cases: water-bubble and air-droplet jets.

  20. Numerical modeling of two-phase binary fluid mixing using mixed finite elements

    KAUST Repository

    Sun, Shuyu

    2012-07-27

    Diffusion coefficients of dense gases in liquids can be measured by considering two-phase binary nonequilibrium fluid mixing in a closed cell with a fixed volume. This process is based on convection and diffusion in each phase. Numerical simulation of the mixing often requires accurate algorithms. In this paper, we design two efficient numerical methods for simulating the mixing of two-phase binary fluids in one-dimensional, highly permeable media. Mathematical model for isothermal compositional two-phase flow in porous media is established based on Darcy\\'s law, material balance, local thermodynamic equilibrium for the phases, and diffusion across the phases. The time-lag and operator-splitting techniques are used to decompose each convection-diffusion equation into two steps: diffusion step and convection step. The Mixed finite element (MFE) method is used for diffusion equation because it can achieve a high-order and stable approximation of both the scalar variable and the diffusive fluxes across grid-cell interfaces. We employ the characteristic finite element method with moving mesh to track the liquid-gas interface. Based on the above schemes, we propose two methods: single-domain and two-domain methods. The main difference between two methods is that the two-domain method utilizes the assumption of sharp interface between two fluid phases, while the single-domain method allows fractional saturation level. Two-domain method treats the gas domain and the liquid domain separately. Because liquid-gas interface moves with time, the two-domain method needs work with a moving mesh. On the other hand, the single-domain method allows the use of a fixed mesh. We derive the formulas to compute the diffusive flux for MFE in both methods. The single-domain method is extended to multiple dimensions. Numerical results indicate that both methods can accurately describe the evolution of the pressure and liquid level. © 2012 Springer Science+Business Media B.V.

  1. Two phase cooling for superconducting magnets

    International Nuclear Information System (INIS)

    Eberhard, P.H.; Gibson, G.A.; Green, M.A.; Ross, R.R.; Smits, R.G.; Taylor, J.D.; Watt, R.D.

    1986-01-01

    Comments on the use of two phase helium in a closed circuit tubular cooling system and some results obtained with the TPC superconducting magnet are given. Theoretical arguments and experimental evidence are given against a previously suggested method to determine helium two phase flow regimes. Two methods to reduce pressure in the magnet cooling tubes during quenches are discussed; (1) lowering the density of helium in the magnet cooling tubes and (2) proper location of pressure relief valves. Some techniques used to protect the refrigerator from too much cold return gas are also mentioned. 10 refs., 1 fig., 5 tabs

  2. Berni Alder and Phase Transitions in Two Dimensions

    Science.gov (United States)

    Kosterlitz, J. Michael

    I do not know Berni Alder as a person, but I feel that I know him well through his seminal paper "Phase Transition in Elastic Disks𠇍 by B. J. Alder and T. E. Wainwright [1962], which was essential in motivating David Thouless and myself to think about phase transitions in two dimensional systems with a continuous symmetry. In the early 1970's, the conventional wisdom was that a crystalline solid could not exist in a two dimensional world because of the rigorous Mermin-Wagner theorem prohibiting true long range translational order at any non-zero temperature. This contradiction was settled by the theory of dislocation mediated melting to an intermediate hexatic phase followed by a second transition to the isotropic fluid at a higher temperature. This scenario, with its associated sophisticated theory, seemed to settle the controversy of two dimensional melting once and for all. However, in our elation at understanding the fundamental physics and the essential excitations of melting in 2D, we had all forgotten that the early work of Berni Alder also showed that this melting involved a weak first order transition while theory now predicted melting by two successive continuous transitions with no discontinuity in area at the critical pressure. This discrepancy could be hand waved away by arguing that Berni's system was far too small and his computers far too slow so that the areal discontinuity could be due to finite size effects or to failing to equilibrate the system. Experiments were not able to resolve the order of the transitions, but seemed to agree quantitatively with theory…

  3. Two-Phase Induction Motor Drives

    Directory of Open Access Journals (Sweden)

    Gholam Reza Arab Markadeh

    2010-10-01

    Full Text Available The lack of variable-speed drives for two (single induction motor is a reality. This article attempts mainly to investigate the reasons for this lack of variable – speed drives. This paper deals with literature survey of various existing converter topologies, which have been proposed for adjustable speed single phase induction motor drives. Various converter topologies have been compared in this paper. Among these converter topologies, the adjustable frequency PWM inverter is the best choice for single-phase induction motor drives. However, adjustable-frequency drives have not been widely used with single-phase Induction motors. The open-loop constant V/F control law cannot be used with the single-phase induction motor drives as it is used with three phase motors. The variation of the operating frequency at lower speed range with constant load torque causes variation in motor's slip. A constant V/F control is suitable only over the upper speed range.

  4. Heavy particle excitation of the 2s22p52P3/2-2s22p52P1/2 transition in fluorine-like Fe XVIII and Ni XX

    International Nuclear Information System (INIS)

    Keenan, F.P.; Reid, R.H.G.

    1989-01-01

    Cross sections and rate coefficients for excitation of the 2s 2 2p 52 P 3/2 -2s 2 2p 52 P 1/2 transition in fluorine-like Fe XVIII and Ni XX by proton (p), deuteron (d), triton (t) and α-particle (α) impact have been calculated using the close-coupled impact parameter method. At temperatures close to or below those of maximum Fe XVIII and Ni XX fractional abundance in ionisation equilibrium, the p,d and t rates are found to be comparable and are much greater than the rates due to α collisions. However, at high temperatures the situation is reversed, with the α rates being about a factor of two larger than those due to the other particles. The effects of adopting the present atomic data in calculations of the electron density or ion temperature sensitive emission line ratios are briefly discussed. (author)

  5. Numerical method for two-phase flow discontinuity propagation calculation

    International Nuclear Information System (INIS)

    Toumi, I.; Raymond, P.

    1989-01-01

    In this paper, we present a class of numerical shock-capturing schemes for hyperbolic systems of conservation laws modelling two-phase flow. First, we solve the Riemann problem for a two-phase flow with unequal velocities. Then, we construct two approximate Riemann solvers: an one intermediate-state Riemann solver and a generalized Roe's approximate Riemann solver. We give some numerical results for one-dimensional shock-tube problems and for a standard two-phase flow heat addition problem involving two-phase flow instabilities

  6. Reversible, on-demand generation of aqueous two-phase microdroplets

    Science.gov (United States)

    Collier, Charles Patrick; Retterer, Scott Thomas; Boreyko, Jonathan Barton; Mruetusatorn, Prachya

    2017-08-15

    The present invention provides methods of on-demand, reversible generation of aqueous two-phase microdroplets core-shell microbeads, microparticle preparations comprising the core-shell microbeads, and drug delivery formulation comprising the microparticle preparations. Because these aqueous microdroplets have volumes comparable to those of cells, they provide an approach to mimicking the dynamic microcompartmentation of biomaterial that naturally occurs within the cytoplasm of cells. Hence, the present methods generate femtoliter aqueous two-phase droplets within a microfluidic oil channel using gated pressure pulses to generate individual, stationary two-phase microdroplets with a well-defined time zero for carrying out controlled and sequential phase transformations over time. Reversible phase transitions between single-phase, two-phase, and core-shell microbead states are obtained via evaporation-induced dehydration and water rehydration.

  7. Forced two phase helium cooling of large superconducting magnets

    International Nuclear Information System (INIS)

    Green, M.A.; Burns, W.A.; Taylor, J.D.

    1979-08-01

    A major problem shared by all large superconducting magnets is the cryogenic cooling system. Most large magnets are cooled by some variation of the helium bath. Helium bath cooling becomes more and more troublesome as the size of the magnet grows and as geometric constraints come into play. An alternative approach to cooling large magnet systems is the forced flow, two phase helium system. The advantages of two phase cooling in many magnet systems are shown. The design of a two phase helium system, with its control dewar, is presented. The paper discusses pressure drop of a two phase system, stability of a two phase system and the method of cool down of a two phase system. The results of experimental measurements at LBL are discussed. Included are the results of cool down and operation of superconducting solenoids

  8. Optimal hysteretic control for a B M A P / S M / 1 / N queue with two operation modes

    Directory of Open Access Journals (Sweden)

    Dudin Alexander N.

    1999-01-01

    Full Text Available We consider B M A P / S M / 1 type queueing system with finite buffer of size N . The system has two operation modes, which are characterized by the matrix generating function of B M A P -input, the kernel of the semi-Markovian service process, and utilization cost. An algorithm for determining the optimal hysteresis strategy is presented.

  9. Effect of Processing Conditions of 75Li2S-25P2S5 Solid Electrolyte on its DC Electrochemical Behavior

    International Nuclear Information System (INIS)

    Garcia-Mendez, Regina; Mizuno, Fuminori; Zhang, Ruigang; Arthur, Timothy S.; Sakamoto, Jeff

    2017-01-01

    Highlights: • The highly conductive thio-LiSICON III analog phase formed when hot pressing LPS between 170–250 °C. • The low conductivity Li 3 PS 4 phase formed when hot pressing LPS at 300 °C. • Obtaining LPS glass-ceramic through hot pressing increased the rate at which current can be passed through the cell before short circuit is observed. • The critical current density is affected by the LPS phase present and adhesion between particles. - Abstract: The effect of processing conditions of the 75Li 2 S-25P 2 S 5 (LPS) on the Li/LPS DC electrochemical stability was investigated. LPS was densified by compacting at room temperature, and hot pressed between 130–300 °C, 47 MPa. The relative density (80% for all samples) was not affected by the hot pressing temperature, which was likely due to insufficient bulk diffusion (at the pressure used within the temperature range selected) to promote densification. The highly conductive meta-stable crystalline phase (thio-LiSICON III analog) precipitated from the mother glass when hot pressing between 170 − 250 °C and the low conductivity Li 3 PS 4 phase formed when hot pressing at 300 °C. The Li/LPS DC electrochemical stability was characterized as a function of current density between 0.01–1.0 mA· cm −2 . Two phenomena were observed; first, as the current density increased, deviation from Ohmic behavior was observed, manifested in an increase in output potential difference. Second, as the current density was further increased, a drop in cell potential was observed followed by an output potential difference instability; likely consistent with short-circuiting caused by Li metal propagation. The highest critical current density, at which short circuit occurs, resulted when hot pressing at 170 °C, reaching 1.0 mA· cm −2 . In general, obtaining LPS glass-ceramic through hot pressing increased the rate at which current can be passed through the cell. It is believed that further atomic

  10. Weak-anisotropy approximations of P-wave phase and ray velocities for anisotropy of arbitrary symmetry

    Czech Academy of Sciences Publication Activity Database

    Farra, V.; Pšenčík, Ivan

    2016-01-01

    Roč. 60, č. 3 (2016), s. 403-418 ISSN 0039-3169 Institutional support: RVO:67985530 Keywords : weak anisotropy * P-wave * phase velocity * ray velocity Subject RIV: DC - Siesmology, Volcanology, Earth Structure Impact factor: 0.764, year: 2016

  11. Film boiling heat transfer from a hot sphere falling in two-phase pool

    International Nuclear Information System (INIS)

    Bang, K. H.; Kim, K. Y.

    1998-01-01

    The purpose of the present study is to experimentally investigate film boiling heat trasfer from a hot sphere falling in steam-water two-phase pool, which is the key heat transfer mode in molten fuel and coolant mixing. To measure film boiling heat transfer coefficients on a spere falling in two-phase pool, a heated sphere with a thermocouple embedded at the center is dropped in a vertical tube filled with steam-water mixture. The present experiment is unique in making the heated sphere fall through the two-phase pool while the previous experiments were performed with stationary spheres in flowing fluid. The falling speed of the sphere is measured using a set of magnet pickup coils distributed along the tube. The ranges of the experimental conditions are: spere fall speed 0-0.5 m/s, average void fraction 0-25,% steam superficial velocity 0-0.25 m/s. The results show that the forced convection film boiling heat transfer coefficient decrease slightly as the steam superficial velocity (void fraction) is increased

  12. Strongly coupled dispersed two-phase flows; Ecoulements diphasiques disperses fortement couples

    Energy Technology Data Exchange (ETDEWEB)

    Zun, I.; Lance, M.; Ekiel-Jezewska, M.L.; Petrosyan, A.; Lecoq, N.; Anthore, R.; Bostel, F.; Feuillebois, F.; Nott, P.; Zenit, R.; Hunt, M.L.; Brennen, C.E.; Campbell, C.S.; Tong, P.; Lei, X.; Ackerson, B.J.; Asmolov, E.S.; Abade, G.; da Cunha, F.R.; Lhuillier, D.; Cartellier, A.; Ruzicka, M.C.; Drahos, J.; Thomas, N.H.; Talini, L.; Leblond, J.; Leshansky, A.M.; Lavrenteva, O.M.; Nir, A.; Teshukov, V.; Risso, F.; Ellinsen, K.; Crispel, S.; Dahlkild, A.; Vynnycky, M.; Davila, J.; Matas, J.P.; Guazelli, L.; Morris, J.; Ooms, G.; Poelma, C.; van Wijngaarden, L.; de Vries, A.; Elghobashi, S.; Huilier, D.; Peirano, E.; Minier, J.P.; Gavrilyuk, S.; Saurel, R.; Kashinsky, O.; Randin, V.; Colin, C.; Larue de Tournemine, A.; Roig, V.; Suzanne, C.; Bounhoure, C.; Brunet, Y.; Tanaka, A.T.; Noma, K.; Tsuji, Y.; Pascal-Ribot, S.; Le Gall, F.; Aliseda, A.; Hainaux, F.; Lasheras, J.; Didwania, A.; Costa, A.; Vallerin, W.; Mudde, R.F.; Van Den Akker, H.E.A.; Jaumouillie, P.; Larrarte, F.; Burgisser, A.; Bergantz, G.; Necker, F.; Hartel, C.; Kleiser, L.; Meiburg, E.; Michallet, H.; Mory, M.; Hutter, M.; Markov, A.A.; Dumoulin, F.X.; Suard, S.; Borghi, R.; Hong, M.; Hopfinger, E.; Laforgia, A.; Lawrence, C.J.; Hewitt, G.F.; Osiptsov, A.N.; Tsirkunov, Yu. M.; Volkov, A.N.

    2003-07-01

    dissipation in particle-driven gravity current; a model for highly concentrated suspensions in a diffusive turbulence. Topic 6: strongly coupled two-phase flows involving reacting flows, phase change: microparticle formation in a reacting flow; crystallization and melting in two-phase flows from a non-equilibrium thermodynamics viewpoint; study of a statistical modeling of turbulent flows with very variable density, application to atomization; breakup mechanisms in coaxial atomization; application of Batchelor's fluidized bed stability analysis for wispy-annular flow; unsteady effects induced by non-uniformities of particle concentration in a two-phase boundary layer; one-way and two-way coupled gas-particle flows over a blunt body: the role of particle particle collisions and the shielding effect; particulate aerosols spreading in the planetary boundary layer on complex terrain. Model development and validation examples.

  13. Two-phase flow measurement by pulsed neutron activation techniques

    International Nuclear Information System (INIS)

    Kehler, P.

    1978-01-01

    The Pulsed Neutron Activation (PNA) technique for measuring the mass flow velocity and the average density of two-phase mixtures is described. PNA equipment can be easily installed at different loops, and PNA techniques are non-intrusive and independent of flow regimes. These features of the PNA technique make it suitable for in-situ measurement of two-phase flows, and for calibration of more conventional two-phase flow measurement devices. Analytic relations governing the various PNA methods are derived. The equipment and procedures used in the first air-water flow measurement by PNA techniques are discussed, and recommendations are made for improvement of future tests. In the present test, the mass flow velocity was determined with an accuracy of 2 percent, and average densities were measured down to 0.08 g/cm 3 with an accuracy of 0.04 g/cm 3 . Both the accuracy of the mass flow velocity measurement and the lower limit of the density measurement are functions of the injected activity and of the total number of counts. By using a stronger neutron source and a larger number of detectors, the measurable density can be decreased by a factor of 12 to .007 g/cm 3 for 12.5 cm pipes, and to even lower ranges for larger pipes

  14. Two phases fermentative process for hydrogen and methane production from cassava wastewater

    Directory of Open Access Journals (Sweden)

    Aryane Mota Oliveira

    2017-04-01

    Full Text Available Introduction: Hydrogen and methane production was investigated in two phases of fermentative process. Objective: At the acidogenic phase, an anaerobic fluidized bed reactor was fed with cassava wastewater producing hydrogen. Methods: Expanded clay was used as a support material for biomass immobilization. The reactor was operated with HRT ranging from 8-1 h. Results: The best hydrogen yield production was 1.91 mol H2/mol glucose at HRT of 2 h. At the methanogenic phase, the acidogenic process effluent fed a fixed-bed reactor producing methane. Conclusion: Sururu (Mytella falcata shells was used as support acted as pH neutralizer in the fixed-bed reactor, yielding best (0.430±0.150 Lmethane/gCOD with 12h HRT phase.

  15. Effects of background noise on inter-trial phase coherence and auditory N1-P2 responses to speech stimuli.

    Science.gov (United States)

    Koerner, Tess K; Zhang, Yang

    2015-10-01

    This study investigated the effects of a speech-babble background noise on inter-trial phase coherence (ITPC, also referred to as phase locking value (PLV)) and auditory event-related responses (AERP) to speech sounds. Specifically, we analyzed EEG data from 11 normal hearing subjects to examine whether ITPC can predict noise-induced variations in the obligatory N1-P2 complex response. N1-P2 amplitude and latency data were obtained for the /bu/syllable in quiet and noise listening conditions. ITPC data in delta, theta, and alpha frequency bands were calculated for the N1-P2 responses in the two passive listening conditions. Consistent with previous studies, background noise produced significant amplitude reduction and latency increase in N1 and P2, which were accompanied by significant ITPC decreases in all the three frequency bands. Correlation analyses further revealed that variations in ITPC were able to predict the amplitude and latency variations in N1-P2. The results suggest that trial-by-trial analysis of cortical neural synchrony is a valuable tool in understanding the modulatory effects of background noise on AERP measures. Copyright © 2015 Elsevier B.V. All rights reserved.

  16. Visualization of two-phase flow in metallic pipes using neutron radiographic technique

    International Nuclear Information System (INIS)

    Luiz, L.C.; Crispim, V.R.

    2007-01-01

    The study of two-phase flow is a matter of great interest both for the engineering and oil industries. The production of oil and natural gas involves the transportation of fluids in their liquid and gaseous states, respectively, to the processing plant for refinement. The forecasting of two-phase flow in oil pipes is of the utmost important yet an extremely difficult task. With the development of the electronic imaging system, installed in J-9 irradiation channel of the IEN/CNEN Argonauta Reactor, it is possible to visualize the different types of two phase air-water flows in small-diameter metallic pipes. After developing the captured image the liquid-gas drift flux correlation as well as the void fraction in relation to the injected air outflow for a fixed water outflow can be obtained. (author)

  17. New theoretical model for two-phase flow discharged from stratified two-phase region through small break

    International Nuclear Information System (INIS)

    Yonomoto, Taisuke; Tasaka, Kanji

    1988-01-01

    A theoretical and experimental study was conducted to understand two-phase flow discharged from a stratified two-phase region through a small break. This problem is important for an analysis of a small break loss-of-coolant accident (LOCA) in a light water reactor (LWR). The present theoretical results show that a break quality is a function of h/h b , where h is the elevation difference between a bulk water level in the upstream region and break and b the suffix for entrainment initiation. This result is consistent with existing eperimental results in literature. An air-water experiment was also conducted changing a break orientation as an experimental parameter to develop and assess the model. Comparisons between the model and the experimental results show that the present model can satisfactorily predict the flow rate and the quality at the break without using any adjusting constant when liquid entrainment occurs in a stratified two-phase region. When gas entrainment occurs, the experimental data are correlated well by using a single empirical constant. (author)

  18. Phenomenological two-nucleon interaction operator

    International Nuclear Information System (INIS)

    Lagaris, I.E.; Pandharipande, V.R.

    1981-01-01

    We report a phenomenological two-nucleon interaction operator obtained by fitting the nucleon-nucleon phase shifts up to 425 MeV in S, P, D and F waves, and the deuteron properties. The operator has the standard eight potentials associated with the two-body operators 1, sigma 1 x sigma 2 , tau 1 x tau 2 , sigma 1 x sigma 2 tau 1 x tau 2 , S 12 , S 12 tau 1 x tau 2 , L x S and L x Stau 2 ; and six phenomenological potentials associated with operators L 2 , L 2 sigma 1 x sigma 2 , L 2 tau 1 x tau 2 , L 2 sigma 1 x sigma 2 tau 1 xtau 2 (L x S) 2 tau 1 x tau 2 . The six quadratic L terms are relatively weak, and are chosen in order to make many-body calculations with this operator simpler. (orig.)

  19. Modelling aspects of two phase flow

    International Nuclear Information System (INIS)

    Mayinger, F.

    1977-01-01

    In two phase flow scaling is much more limited to very narrowly defined physical phenomena than in single phase fluids. For complex and combined phenomena it can be achieved not by using dimensionless numbers alone but in addition a detailed mathematical description of the physical problem - usually in the form of a computer program - must be available. An important role plays the scaling of the thermodynamic data of the modelling fluid. From a literature survey and from own scaling experiments the conclusion can be drawn that Freon is a quite suitable modelling fluid for scaling steam-water mixtures. However, whithout a theoretical description of the phenomena nondimensional numbers for scaling two phase flow must be handled very carefully. (orig.) [de

  20. Geometric analysis of the solutions of two-phase flows: two-fluid model

    International Nuclear Information System (INIS)

    Kestin, J.; Zeng, D.L.

    1984-01-01

    This report contains a lightly edited draft of a study of the two-fluid model in two-phase flow. The motivation for the study stems from the authors' conviction that the construction of a computer code for any model should be preceded by a geometrical analysis of the pattern of trajectories in the phase space appropriate for the model. Such a study greatly facilitates the understanding of the phenomenon of choking and anticipates the computational difficulties which arise from the existence of singularities. The report contains a derivation of the six conservation equations of the model which includes a consideration of the simplifications imposed on a one-dimensional treatment by the presence of boundary layers at the wall and between the phases. The model is restricted to one-dimensional adiabatic flows of a single substance present in two phases, but thermodynamic equilibrium between the phases is not assumed. The role of closure conditions is defined but no specific closure conditions, or explicit equations of state, are introduced

  1. Two-phase flow instrumentation research at RPI

    International Nuclear Information System (INIS)

    Lahey, R.T. Jr.; Krycuk, G.

    1979-01-01

    Novel instrumentation for the measurement of void fraction and phase velocity was developed. An optical digital interferometer and a dual beam x-ray equipment were designed for detection of voids. Pitot tube measurements were made to understand two-phase flow phenomena in liquid phase velocity

  2. Studying Suspended Sediment Mechanism with Two-Phase PIV

    Science.gov (United States)

    Matinpour, H.; Atkinson, J. F.; Bennett, S. J.; Guala, M.

    2017-12-01

    Suspended sediment transport affects soil erosion, agriculture and water resources quality. Turbulent diffusion is the most primary force to maintain sediments in suspension. Although extensive previous literature have been studying the interactions between turbulent motion and suspended sediment, mechanism of sediments in suspension is still poorly understood. In this study, we investigate suspension of sediments as two distinct phases: one phase of sediments and another phase of fluid with turbulent motions. We designed and deployed a state-of-the-art two-phase PIV measurement technique to discriminate these two phases and acquire velocities of each phase separately and simultaneously. The technique that we have developed is employing a computer-vision based method, which enables us to discriminate sediment particles from fluid tracer particles based on two thresholds, dissimilar particle sizes and different particle intensities. Results indicate that fluid turbulence decreases in the presence of suspended sediments. Obtaining only sediment phase consecutive images enable us to compute fluctuation sediment concentration. This result enlightens understanding of complex interaction between the fluctuation velocities and the fluctuation of associated mass and compares turbulent viscosity with turbulent eddy diffusivity experimentally.

  3. Isoelectronic comparison of the Al-like 3s23p 2P-3s3p24P transitions in the ions P III-Mo XXX

    International Nuclear Information System (INIS)

    Jupen, C.; Curtis, L.J.

    1996-01-01

    New observations of the 3s 2 3p 2 P-3s3p 2 4 P intercombination transitions in Al-like ions have been made for Cl V from spark spectra recorded at Lund and for Kr XXIV and Mo XXX from spectra obtained at the JET tokamak. The new results have been combined with other identifications of these transitions along the sequence and empirically systematized and compared with theoretical calculations. A set of smoothed and interpolated values for the excitation energies of the 3s3p 2 4 P levels in P III-Mo XXX is presented. (orig.)

  4. Precortical phase of Alzheimer’s disease (AD)-related tau cytoskeletal pathology

    Science.gov (United States)

    Stratmann, Katharina; Heinsen, Helmut; Korf, Horst-Werner; Del Turco, Domenico; Ghebremedhin, Estifanos; Seidel, Kay; Bouzrou, Mohamed; Grinberg, Lea T.; Bohl, Jürgen; Wharton, Stephen B; den Dunnen, Wilfred; Rüb, Udo

    2015-01-01

    Alzheimer’s disease (AD) represents the most frequent progressive neuropsychiatric disorder worldwide leading to dementia and accounts for 60 to 70% of demented individuals. In view of the early appearance of neuronal deposits of the hyperphosphorylated cytoskeletal protein tau in the transentorhinal and entorhinal regions of the allocortex (i.e. in Braak and Braak AD stage I in the evolution of the AD-related cortical tau cytoskeletal pathology) it has been believed for a long time that these allocortical regions represent the first brain targets of the AD-related tau cytoskeletal pathology. However, recent pathoanatomical studies suggested that the subcortical brain nuclei that send efferent projections to the transentorhinal and entorhinal regions may also comprise AD-related cytoskeletal changes already at very early Braak and Braak AD stages. In order to corroborate these initial results we systematically investigated the presence and extent of the AD-related cytoskeletal pathology in serial thick tissue sections through all the subcortical nuclei known to send efferent projections to these vulnerable allocortical regions of three individuals with Braak and Braak AD stage 0 and fourteen individuals with Braak and Braak AD stage I by means of immunostainings with the anti-tau antibody AT8. These investigations revealed consistent AT8 immunoreactive neuronal tau cytoskeletal pathology in a subset of these subcortical nuclei (i.e. medial septal nucleus, nuclei of the vertical and horizontal limbs of the diagonal band of Broca, basal nucleus of Meynert; claustrum; hypothalamic ventromedial, tuberomamillary and supramamillary nuclei, perifornical region and lateral area; thalamic central medial, laterodorsal, subparafascicular, and central lateral nuclei, medial pulvinar and limitans-suprageniculate complex; peripeduncular nucleus, dopaminergic substantia nigra and ventral tegmental area, periaqueductal gray, midbrain and pontine dorsal raphe nuclei, locus

  5. Separation of S-wave pseudoscalar and pseudovector amplitudes in {pi}{sup -}p{yields}{pi}{sup +}{pi}{sup -}n reaction on polarized target

    Energy Technology Data Exchange (ETDEWEB)

    Kaminski, R.; Lesniak, L.; Rybicki, K. [Institute of Nuclear Physics, Cracow (Poland)

    1996-06-01

    A new analysis of S-wave production amplitudes for the reaction {pi}{sup -}p{yields}{pi}{sup +}{pi}{sup -}n on a transversely polarized target is performed. It is based on the results obtained by CERN-Cracow-Munich collaboration in the {pi}{pi} energy range from 600 MeV to 1600 MeV at 17.2 GeV/c {pi}{sup -} momentum. Energy-independent separation of the S-wave pseudoscalar amplitude ({pi} exchange) from the pseudovector amplitude (a{sub 1} exchange) is carried out using assumptions much weaker than those in all previous analyses. We show that, especially around 1000 MeV and around 1500 MeV, the a{sub 1} exchange amplitude cannot be neglected. The scalar-isoscalar {pi}{pi} phase shift are calculated using fairly weak assumptions. Our results are consistent both with the so called ``up`` and the well-known ``down`` solution, provided we choose those in which the S-wave phases increase slower with the effective {pi}{pi} mass than the P-wave phases. Above 1420 MeV both sets of phase shifts increase with energy faster than in the experiment on an unpolarized target. This fact can be related to the presence of scalar resonance f{sub o}(1500). (author). 41 refs, 9 figs, 1 tab.

  6. Intracellular S1P generation is essential for S1P-induced motility of human lung endothelial cells: role of sphingosine kinase 1 and S1P lyase.

    Directory of Open Access Journals (Sweden)

    Evgeny V Berdyshev

    Full Text Available BACKGROUND: Earlier we have shown that extracellular sphingosine-1-phosphate (S1P induces migration of human pulmonary artery endothelial cells (HPAECs through the activation of S1P(1 receptor, PKCε, and PLD2-PKCζ-Rac1 signaling cascade. As endothelial cells generate intracellular S1P, here we have investigated the role of sphingosine kinases (SphKs and S1P lyase (S1PL, that regulate intracellular S1P accumulation, in HPAEC motility. METHODOLOGY/PRINCIPAL FINDINGS: Inhibition of SphK activity with a SphK inhibitor 2-(p-Hydroxyanilino-4-(p-Chlorophenyl Thiazole or down-regulation of Sphk1, but not SphK2, with siRNA decreased S1P(int, and attenuated S1P(ext or serum-induced motility of HPAECs. On the contrary, inhibition of S1PL with 4-deoxypyridoxine or knockdown of S1PL with siRNA increased S1P(int and potentiated motility of HPAECs to S1P(ext or serum. S1P(ext mediates cell motility through activation of Rac1 and IQGAP1 signal transduction in HPAECs. Silencing of SphK1 by siRNA attenuated Rac1 and IQGAP1 translocation to the cell periphery; however, knockdown of S1PL with siRNA or 4-deoxypyridoxine augmented activated Rac1 and stimulated Rac1 and IQGAP1 translocation to cell periphery. The increased cell motility mediated by down-regulation was S1PL was pertussis toxin sensitive suggesting "inside-out" signaling of intracellularly generated S1P. Although S1P did not accumulate significantly in media under basal or S1PL knockdown conditions, addition of sodium vanadate increased S1P levels in the medium and inside the cells most likely by blocking phosphatases including lipid phosphate phosphatases (LPPs. Furthermore, addition of anti-S1P mAb to the incubation medium blocked S1P(ext or 4-deoxypyridoxine-dependent endothelial cell motility. CONCLUSIONS/SIGNIFICANCE: These results suggest S1P(ext mediated endothelial cell motility is dependent on intracellular S1P production, which is regulated, in part, by SphK1 and S1PL.

  7. Observation of the strongest 5s2 5p6 5d-(5s2 5p5 5d6s+5s25p6 7p) transitions in Au XI to Bi XV ions

    International Nuclear Information System (INIS)

    Churilov, S.S.; Joshi, Y.N.

    2001-01-01

    The spectra of gold till bismuth were studied in the 90-135 A region. Nine most intense lines belonging to the 5s 2 5p 6 5d-5s 2 5p 5 5d6s array were identified in Au XI to Bi XV ions. The 5s 2 5p 6 7p 2 P 3/2,1/2 levels in Au XI and the 5s 2 5p 6 7p 2 P 3/2 level in Hg XII were also identified. The observed wavelengths and intensities agree quite well with the Hartree-Fock calculations. (orig.)

  8. Electronic properties of in-plane phase engineered 1T'/2H/1T' MoS2

    Science.gov (United States)

    Thakur, Rajesh; Sharma, Munish; Ahluwalia, P. K.; Sharma, Raman

    2018-04-01

    We present the first principles studies of semi-infinite phase engineered MoS2 along zigzag direction. The semiconducting (2H) and semi-metallic (1T') phases are known to be stable in thin-film MoS2. We described the electronic and structural properties of the infinite array of 1T'/2H/1T'. It has been found that 1T'phase induced semi-metallic character in 2H phase beyond interface but, only Mo atoms in 2H phase domain contribute to the semi-metallic nature and S atoms towards semiconducting state. 1T'/2H/1T' system can act as a typical n-p-n structure. Also high holes concentration at the interface of Mo layer provides further positive potential barriers.

  9. Implications of S-phase exchanges for the mechanisms of radiosensitivity in trisomy 21

    International Nuclear Information System (INIS)

    Athanasiou, K.; Bartsocas, C.S.

    1982-01-01

    Human lymphocytes obtained from four patients with Down syndrome and from two normal individuals were irradiated with X-rays during their S phase and examined for chromatid type aberrations. It is suggested that the significantly increased frequency of asymmetrical chromatid interchanges found in trisomic cells is related to an altered DNA repair system. This altered repair system is probably responsible for the increased frequency of chromosome aberrations that can be induced in these cells by x-rays and the increased tendency for leukemia observed in Down syndrome as well

  10. Number-Phase Wigner Representation and Entropic Uncertainty Relations for Binomial and Negative Binomial States

    International Nuclear Information System (INIS)

    Amitabh, J.; Vaccaro, J.A.; Hill, K.E.

    1998-01-01

    We study the recently defined number-phase Wigner function S NP (n,θ) for a single-mode field considered to be in binomial and negative binomial states. These states interpolate between Fock and coherent states and coherent and quasi thermal states, respectively, and thus provide a set of states with properties ranging from uncertain phase and sharp photon number to sharp phase and uncertain photon number. The distribution function S NP (n,θ) gives a graphical representation of the complimentary nature of the number and phase properties of these states. We highlight important differences between Wigner's quasi probability function, which is associated with the position and momentum observables, and S NP (n,θ), which is associated directly with the photon number and phase observables. We also discuss the number-phase entropic uncertainty relation for the binomial and negative binomial states and we show that negative binomial states give a lower phase entropy than states which minimize the phase variance

  11. Experimental study of two-phase flow using shadowgraphy and IPI technique

    Czech Academy of Sciences Publication Activity Database

    Jašíková, D.; Kotek, M.; Kysela, Bohuš; Šulc, R.; Kopecký, V.

    2017-01-01

    Roč. 2, č. 2017 (2017), s. 107-114 ISSN 2367-8992 R&D Projects: GA ČR GA16-20175S Grant - others:GA MŠk(CZ) LO1201 Institutional support: RVO:67985874 Keywords : mixing process * two-phase flow * shadowgraphy * interferometric particle imaging * visualization Subject RIV: JP - Industrial Processing OBOR OECD: Fluids and plasma physics (including surface physics) http://www.iaras.org/iaras/filedownloads/ijtam/2017/009-0020(2017).pdf

  12. Two-phase LMMHD mixer-development experiments

    International Nuclear Information System (INIS)

    Fabris, G.; Dunn, P.F.; Chow, J.C.F.

    1978-01-01

    The results of a series of experiments conducted to evaluate the fluid mechanical performance of various two-phase LMMHD mixer designs are presented. The results from both flow visualization studies of the local two-phase flows downstream from various mixer-element configurations and local measurements performed to characterize these flows are presented. A conceptual LMMHD mixer design is described that insures the generation of small bubbles, prevents the formation of gas slugs and separated regions, and favors the stabilization of a homogeneous foam flow

  13. Lagrangian analysis of two-phase hydrodynamic and nuclear-coupled density-wave oscillations

    International Nuclear Information System (INIS)

    Lahey, R.T. Jr.; Yadigaroglu, G.

    1974-01-01

    The mathematical technique known as the ''method of characteristics'' has been used to construct an exact, analytical solution to predict the onset of density-wave oscillations in diabatic two-phase systems, such as Boiling Water Nuclear Reactors (BWR's). Specifically, heater wall dynamics, boiling boundary dynamics and nuclear kinetics have been accounted for in this analysis. Emphasis is placed on giving the reader a clear physical understanding of the phenomena of two-phase density-wave oscillations. Explanations are presented in terms of block diagram logic, and phasor representations of the various pressure drop perturbations are given. (U.S.)

  14. Experimental on two sensors combination used in horizontal pipe gas-water two-phase flow

    International Nuclear Information System (INIS)

    Wu, Hao; Dong, Feng

    2014-01-01

    Gas-water two phase flow phenomenon widely exists in production and living and the measurement of it is meaningful. A new type of long-waist cone flow sensor has been designed to measure two-phase mass flow rate. Six rings structure of conductance probe is used to measure volume fraction and axial velocity. The calibration of them have been made. Two sensors have been combined in horizontal pipeline experiment to measure two-phase flow mass flow rate. Several model of gas-water two-phase flow has been discussed. The calculation errors of total mass flow rate measurement is less than 5% based on the revised homogeneous flow model

  15. Nonclassicality in phase-number uncertainty relations

    International Nuclear Information System (INIS)

    Matia-Hernando, Paloma; Luis, Alfredo

    2011-01-01

    We show that there are nonclassical states with lesser joint fluctuations of phase and number than any classical state. This is rather paradoxical since one would expect classical coherent states to be always of minimum uncertainty. The same result is obtained when we replace phase by a phase-dependent field quadrature. Number and phase uncertainties are assessed using variance and Holevo relation.

  16. Nonclassicality in phase-number uncertainty relations

    Energy Technology Data Exchange (ETDEWEB)

    Matia-Hernando, Paloma; Luis, Alfredo [Departamento de Optica, Facultad de Ciencias Fisicas, Universidad Complutense, 28040 Madrid (Spain)

    2011-12-15

    We show that there are nonclassical states with lesser joint fluctuations of phase and number than any classical state. This is rather paradoxical since one would expect classical coherent states to be always of minimum uncertainty. The same result is obtained when we replace phase by a phase-dependent field quadrature. Number and phase uncertainties are assessed using variance and Holevo relation.

  17. Dynamic Phase Boundary Estimation in Two-phase Flows Based on Electrical Impedance Tomography

    International Nuclear Information System (INIS)

    Lee, Jeong Seong; Muhammada, Nauman Malik; Kim, Kyung Youn; Kim, Sin

    2008-01-01

    For the dynamic visualization of the phase boundary in two-phase flows, the electrical impedance tomography (EIT) technique is introduced. In EIT, a set of predetermined electrical currents is injected through the electrodes placed on the boundary of the flow passage and the induced electrical potentials are measured on the electrodes. With the relationship between the injected currents and the induced voltages, the electrical conductivity distribution across the flow domain is estimated through the image reconstruction algorithm where the conductivity distribution corresponds to the phase distribution. In the application of EIT to two-phase flows where there are only two conductivity values, the conductivity distribution estimation problem can be transformed into the boundary estimation problem. This paper considers phase boundary estimation with EIT in annular two-phase flows. As the image reconstruction algorithm, the unscented Kalman filter (UKF) is adopted since from the control theory it is reported that the UKF shows better performance than the extended Kalman filter (EKF) that has been commonly used. For the present problem, the formulation of UKF algorithm involved its incorporation in the adopted image reconstruction algorithm. Also, phantom experiments have been conducted to evaluate the improvement reported by UKF

  18. 4s24p3--4s4p4 and 4s24p3--4s2fp25s transitions in Y VII, Zr VIII, Nb IX, and MoX

    International Nuclear Information System (INIS)

    Reader, J.; Acquista, N.

    1981-01-01

    Spectra of ionized Y, Zr, Nb, and Mo have been observed in sliding-spark and triggered-spark discharges on 10.7-m normal- and grazing-incidence spectrographs at the National Bureau of Standards in Washington, D. C. From these observations the 4s 2 4p 3 --4s4p 4 transitions in Y VII, Zr VIII, Nb IX, and Mo X have been identified. The 4s 2 4p 3 --4s 2 4p 2 5s transitions in Y VII-Mo X, previously identified by Rahimullah et al. [Phys. Scr. 14, 221--223 (1976); 18, 96--106 (1978)], have been confirmed. In Y VII the 4s 2 4p 3 --4s 2 4p 2 6s and 4s4p 4 --4p 5 transition also have been found. The parameters obtained from least-squares fits to the energy levels are compared with Hartree--Fock calculations. Preliminary values of the ionization energies have been determined as 110.02 +- 0.15 eV for Y VII, 133.7 +- 0.5 eV for Zr VIII, 159.2 +- 0.7 eV for Nb IX, and 186.4 +- 1.2 eV for Mo X

  19. Circulating levels of p,p'-DDE are related to prevalent hypertension in the elderly

    International Nuclear Information System (INIS)

    Lind, P. Monica; Penell, Johanna; Salihovic, Samira; Bavel, Bert van; Lind, Lars

    2014-01-01

    Background: Polychlorinated biphenyls (PCBs) and dioxin given to experimental animals increase the blood pressure. We therefore investigated if circulating levels of persistent organic pollutants (POPs) were related to hypertension in a population-based sample of men and women. Methods: One thousand and sixteen subjects aged 70 years were investigated in the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study. Twenty-three POPs were analyzed using high-resolution gas chromatography/high-resolution mass spectrometry (HRGC/HRMS). Hypertension was defined as a systolic blood pressure ≥140 mmHg or a diastolic blood pressure ≥90 mmHg, and/or use of antihypertensive medication. Results: Seven hundred and thirty-two subjects (72%) showed hypertension. When the POPs were treated as continuous variables and adjusted for gender only, two PCBs with a low number of chlorine atoms (PCB 105 and 118) were related to prevalent hypertension. Also the OC pesticide p,p'-DDE was related to hypertension. The strongest of these associations was seen for p,p'-DDE (OR 1.35 for a 1 SD change, 95% CI 1.17–1.56, p<0.0001). Following further adjustment also for BMI, smoking status, education level and exercise habits, only p,p'-DDE was still significantly related to hypertension (OR 1.23 for a 1 SD change, 95% CI 1.06–1.43, p=0.006). Conclusion: In this cross-sectional analysis of an elderly population, high levels of circulating levels of p,p'-DDE were associated with prevalent hypertension, further strengthening the experimental findings that POPs might influence blood pressure. - Highlights: • We evaluated the relation between POPs and hypertension. • Cross sectional data from a cohort of elderly men and women were analyzed. • The main exposure was circulating levels of 23 different POPs. • Hypertension was defined as ≥140/90 mmHg and/or antihypertensive treatment. • High levels of p,p'-DDE were associated with prevalent hypertension

  20. S100A4 interacts with p53 in the nucleus and promotes p53 degradation.

    Science.gov (United States)

    Orre, L M; Panizza, E; Kaminskyy, V O; Vernet, E; Gräslund, T; Zhivotovsky, B; Lehtiö, J

    2013-12-05

    S100A4 is a small calcium-binding protein that is commonly overexpressed in a range of different tumor types, and it is widely accepted that S100A4 has an important role in the process of cancer metastasis. In vitro binding assays has shown that S100A4 interacts with the tumor suppressor protein p53, indicating that S100A4 may have additional roles in tumor development. In the present study, we show that endogenous S100A4 and p53 interact in complex samples, and that the interaction increases after inhibition of MDM2-dependent p53 degradation using Nutlin-3A. Further, using proximity ligation assay, we show that the interaction takes place in the cell nucleus. S100A4 knockdown experiments in two p53 wild-type cell lines, A549 and HeLa, resulted in stabilization of p53 protein, indicating that S100A4 is promoting p53 degradation. Finally, we demonstrate that S100A4 knockdown leads to p53-dependent cell cycle arrest and increased cisplatin-induced apoptosis. Thus, our data add a new layer to the oncogenic properties of S100A4 through its inhibition of p53-dependent processes.

  1. Prediction of n-α phase shifts and inelasticities from p-α data between 20 and 55 MeV

    International Nuclear Information System (INIS)

    Froehlich, J.; Kriesche, H.; Streit, L.

    1980-01-01

    Scattering processes with charged constituents are more readily performed than those involving neutral particles. As a consequence the authors attempt to calculate the interaction data (phase shifts, inelasticities etc.) of such relatively inaccessible processes on the basis of their better known mirror reactions which involve charged particles only. In this case n-α phase shifts (and inelasticities) are determined from those given for p-α. To do this, the effects of Coulomb scattering must be subtracted from the observed pphase shifts. (Auth.)

  2. Novel phases and superconductivity of tin sulfide compounds

    Science.gov (United States)

    Gonzalez, Joseph M.; Nguyen-Cong, Kien; Steele, Brad A.; Oleynik, Ivan I.

    2018-05-01

    Tin sulfides, SnxSy, are an important class of materials that are actively investigated as novel photovoltaic and water splitting materials. A first-principles evolutionary crystal structure search is performed with the goal of constructing the complete phase diagram of SnxSy and discovering new phases as well as new compounds of varying stoichiometry at ambient conditions and pressures up to 100 GPa. The ambient phase of SnS2 with P 3 ¯ m 1 symmetry remains stable up to 28 GPa. Another ambient phase, SnS, experiences a series of phase transformations including α-SnS to β-SnS at 9 GPa, followed by β-SnS to γ-SnS at 40 GPa. γ-SnS is a new high-pressure metallic phase with P m 3 ¯ m space group symmetry stable up to 100 GPa, which becomes a superconductor with a maximum Tc = 9.74 K at 40 GPa. Another new metallic compound, Sn3S4 with I 4 ¯ 3 d space group symmetry, is predicted to be stable at pressures above 15 GPa, which also becomes a superconductor with relatively high Tc = 21.9 K at 30 GPa.

  3. Two-phase flow heat transfer in nuclear reactor systems

    International Nuclear Information System (INIS)

    Koncar, Bostjan; Krepper, Eckhard; Bestion, Dominique; Song, Chul-Hwa; Hassan, Yassin A.

    2013-01-01

    Complete text of publication follows: Heat transfer and phase change phenomena in two-phase flows are often encountered in nuclear reactor systems and are therefore of paramount importance for their optimal design and safe operation.The complex phenomena observed especially during transient operation of nuclear reactor systems necessitate extensive theoretical and experimental investigations. This special issue brings seven research articles of high quality. Though small in number, they cover a wide range of topics, presenting high complexity and diversity of heat transfer phenomena in two-phase flow. In the last decades a vast amount of research has been devoted to theoretical work and computational simulations, yet the experimental work remains indispensable for understanding of two-phase flow phenomena and for model validation purposes. This is reflected also in this issue, where only one article is purely experimental, while three of them deal with theoretical modelling and the remaining three with numerical simulations. The experimental investigation of the critical heat flux (CHF) phenomena by means of photographic study is presented in the paper of J. Park et al. They have used a high-speed camera system to observe the transient boiling characteristics on a thin horizontal cylinder submerged in a pool of water or highly wetting liquid. Experiments show that the initial boiling process is strongly affected by the properties and wettability of the liquid. The authors have stressed the importance of the local scale observation leading to better understanding of the transient CHF phenomena. In the article of G. Espinosa-Paredes et al. a theoretical work concerning the derivation of transport equations for two-phase flow is presented. The author proposes a novel approach based on derivation of nonlocal volume averaged equations which contain new terms related to nonlocal transport effects. These non-local terms act as coupling elements between the phenomena

  4. Generalized nonequilibrium capillary relations for two-phase flow through heterogeneous media.

    Science.gov (United States)

    Amaziane, Brahim; Milišić, Josipa Pina; Panfilov, Mikhail; Pankratov, Leonid

    2012-01-01

    For two-phase flow in porous media, the natural medium heterogeneity necessarily gives rise to capillary nonequilibrium effects. The relaxation to the equilibrium is a slow process which should be introduced in macroscopic flow models. Many nonequilibrium models are based on a phenomenological approach. At the same time there exists a rigorous mathematical way to develop the nonequilibrium equations. Its formalism, developed by Bourgeat and Panfilov [Computational Geosciences 2, 191 (1998)], is based on the homogenization of the microscale flow equations over medium heterogeneities. In contrast with the mentioned paper, in which the case of a sufficiently fast relaxation was analyzed, we consider the case of long relaxation, which leads to the appearance of long-term memory on the macroscale. Due to coupling between the nonlinearity and nonlocality in time, the macroscopic model remains, however, incompletely homogenized, in the general case. At the same time, frequently only the relationship for the nonequilibrium capillary pressure is of interest for applications. In the present paper, we obtain such an exact relationship in two different independent forms for the case of long-term memory. This relationship is more general than that obtained by Bourgeat and Panfilov. In addition, we prove the comparison theorem which determines the upper and lower bounds for the macroscopic model. These bounds represent linear flow models, which are completely homogenized. The results obtained are illustrated by numerical simulations.

  5. Measurement of the CP violating phase φs and the decay width difference ΔΓs in the decay B0s→J/ψφ with the ATLAS experiment

    International Nuclear Information System (INIS)

    Heller, Claudio

    2013-01-01

    A feature of the neutral B 0 s meson is that it can oscillate into its antiparticle before it decays, which can give rise to CP violation due to interference of the two processes mixing and decay. The time-dependent B 0 s →J/ψφ decay is characterized by the decay width Γ s and the decay width difference ΔΓ s . The B 0 s - anti B 0 s oscillation is governed by the mass difference Δm s , and the CP violation is described by the relative phase φ s between the mixing and the decay. The analysis of the decay channel provides the possibility to test the predictions of the Standard Model of particle physics for those parameters. In particular the measurement of the CP violating phase φ s has the capability to unveil enhancement of the small Standard Model value by New Physics. In this thesis the measurement of φ s , Γ s and ΔΓ s in the decay B 0 s → J/ψφ is presented. The analysis makes use of an integrated luminosity of 4.9 fb -1 that was collected with the ATLAS detector in p - p collision produced by the LHC at a center-of-mass energy of √(s)=7 TeV. After the reconstruction and selection of the decay channel, a time-dependent angular analysis of the B 0 s →J/ψφ decay is performed. An untagged as well as a tagged analysis, using opposite side flavor tagging to determine the production flavor of the B 0 s mesons, are presented. The parameters of interest are extracted through the application of an unbinned maximum likelihood fit method, which takes detector efficiency and resolution effects into account. A possible contribution from S-wave decays to the data sample as well as the contamination due to reflections from B 0 d decays are incorporated in the fit. The result of the measurement is found to be consistent with the Standard Model prediction and is presented as 68 %, 90% and 95% confidence regions in the φ s -ΔΓ s plane.

  6. Computational methods for two-phase flow and particle transport

    CERN Document Server

    Lee, Wen Ho

    2013-01-01

    This book describes mathematical formulations and computational methods for solving two-phase flow problems with a computer code that calculates thermal hydraulic problems related to light water and fast breeder reactors. The physical model also handles the particle and gas flow problems that arise from coal gasification and fluidized beds. The second part of this book deals with the computational methods for particle transport.

  7. Microfluidic Manufacturing of Polymeric Nanoparticles: Comparing Flow Control of Multiscale Structure in Single-Phase Staggered Herringbone and Two-Phase Reactors.

    Science.gov (United States)

    Xu, Zheqi; Lu, Changhai; Riordon, Jason; Sinton, David; Moffitt, Matthew G

    2016-12-06

    We compare the microfluidic manufacturing of polycaprolactone-block-poly(ethylene oxide) (PCL-b-PEO) nanoparticles (NPs) in a single-phase staggered herringbone (SHB) mixer and in a two-phase gas-liquid segmented mixer. NPs generated from two different copolymer compositions in both reactors and at three different flow rates, along with NPs generated using a conventional bulk method, are compared with respect to morphologies, dimensions, and internal crystallinities. Our work, the first direct comparison between alternate microfluidic NP synthesis methods, shows three key findings: (i) NP morphologies and dimensions produced in the bulk are different from those produced in a microfluidic mixer, whereas NP crystallinities produced in the bulk and in the SHB mixer are similar; (ii) NP morphologies, dimensions, and crystallinities produced in the single-phase SHB and two-phase mixers at the lowest flow rate are similar; and (iii) NP morphologies, dimensions, and crystallinities change with flow rate in the two-phase mixer but not in the single-phase SHB mixer. These findings provide new insights into the relative roles of mixing and shear in the formation and flow-directed processing of polymeric NPs in microfluidics, informing future reactor designs for manufacturing NPs of low polydispersity and controlled multiscale structure and function.

  8. Direct Measurement of pH in Individual Particles via Raman Microspectroscopy and Variation in Acidity with Relative Humidity.

    Science.gov (United States)

    Rindelaub, Joel D; Craig, Rebecca L; Nandy, Lucy; Bondy, Amy L; Dutcher, Cari S; Shepson, Paul B; Ault, Andrew P

    2016-02-18

    Atmospheric aerosol acidity is an important characteristic of aqueous particles, which has been linked to the formation of secondary organic aerosol by catalyzing reactions of oxidized organic compounds that have partitioned to the particle phase. However, aerosol acidity is difficult to measure and traditionally estimated using indirect methods or assumptions based on composition. Ongoing disagreements between experiments and thermodynamic models of particle acidity necessitate improved fundamental understanding of pH and ion behavior in high ionic strength atmospheric particles. Herein, Raman microspectroscopy was used to determine the pH of individual particles (H2SO4+MgSO4) based on sulfate and bisulfate concentrations determined from νs(SO4(2-)) and νs(HSO4(-)), the acid dissociation constant, and activity coefficients from extended Debye-Hückel calculations. Shifts in pH and peak positions of νs(SO4(2-)) and νs(HSO4(-)) were observed as a function of relative humidity. These results indicate the potential for direct spectroscopic determination of pH in individual particles and the need to improve fundamental understanding of ion behavior in atmospheric particles.

  9. Incorporation of phosphorus guest ions in the calcium silicate phases of Portland cement from 31P MAS NMR spectroscopy.

    Science.gov (United States)

    Poulsen, Søren L; Jakobsen, Hans J; Skibsted, Jørgen

    2010-06-21

    Portland cements may contain small quantities of phosphorus (typically below 0.5 wt % P(2)O(5)), originating from either the raw materials or alternative sources of fuel used to heat the cement kilns. This work reports the first (31)P MAS NMR study of anhydrous and hydrated Portland cements that focuses on the phase and site preferences of the (PO(4))(3-) guest ions in the main clinker phases and hydration products. The observed (31)P chemical shifts (10 to -2 ppm), the (31)P chemical shift anisotropy, and the resemblance of the lineshapes in the (31)P and (29)Si MAS NMR spectra strongly suggest that (PO(4))(3-) units are incorporated in the calcium silicate phases, alite (Ca(3)SiO(5)) and belite (Ca(2)SiO(4)), by substitution for (SiO(4))(4-) tetrahedra. This assignment is further supported by a determination of the spin-lattice relaxation times for (31)P in alite and belite, which exhibit the same ratio as observed for the corresponding (29)Si relaxation times. From simulations of the intensities, observed in inversion-recovery spectra for a white Portland cement, it is deduced that 1.3% and 2.1% of the Si sites in alite and belite, respectively, are replaced by phosphorus. Charge balance may potentially be achieved to some extent by a coupled substitution mechanism where Ca(2+) is replaced by Fe(3+) ions, which may account for the interaction of the (31)P spins with paramagnetic Fe(3+) ions as observed for the ordinary Portland cements. A minor fraction of phosphorus may also be present in the separate phase Ca(3)(PO(4))(2), as indicated by the observation of a narrow resonance at delta((31)P) = 3.0 ppm for two of the studied cements. (31)P{(1)H} CP/MAS NMR spectra following the hydration of a white Portland cement show that the resonances from the hydrous phosphate species fall in the same spectral range as observed for (PO(4))(3-) incorporated in alite. This similarity and the absence of a large (31)P chemical shift ansitropy indicate that the hydrous (PO(4

  10. Inhibition of G1-phase arrest induced by ionizing radiation in hematopoietic cells by overexpression of genes involved in the G1/S-phase transition

    International Nuclear Information System (INIS)

    Epperly, M.; Berry, L.; Halloran, A.; Greenberger, J.S.

    1995-01-01

    D-type cyclins and cyclin-dependent kinase (cdk-4) are likely involved in regulating passage of cells through the G 1 phase of the cell cycle. A decrease in the proportion of cells in G 1 , a relatively radiation-sensitive phase of the cell cycle, should result in increased resistance to ionizing radiation; however, the effect of such overexpression on X-ray-induced G 1 -phase arrest is not known. Radiation survival curves were obtained at a dose rate of either 8 cGy/min or 1 Gy/min for subclones of the IL-3-dependent hematopoietic progenitor cell line 32D cl 3 expressing transgenes for either cyclin-D1, D2 or D3 or cdk-4. We compared the results to those with overexpression of the transgene for Bcl-2, whose expression enhances radiation survival and delays apoptosis. Cells overexpressing transgenes for each D-type cyclin or Bcl-2 had an increased number of cells in S phase compared to parent line 32D cl 3; however, overexpression of cdk-4 had no effect on cell cycle distribution. Cell death resulting from withdrawal of IL-3 was not affected by overexpression of D2, cdk-4 or Bcl-2. Flow cytometry 24 h after 5 Gy irradiation demonstrated that overexpression of each G 1 -phase regulatory transgene decreased the proportion of cells at the G 1 /S-phase border. Western analysis revealed induction of cyclin-D protein levels by irradiation, but no change in the D O , but a significant increase in the rvec n for cyclin-D or cdk-4 transgene-overexpressing clones at 1 Gy/min (P 1 /S-phase arrest. 31 refs., 4 figs., 4 tabs

  11. Thermodynamic properties of hydrated cement phases: C-S-H, C-A-S-H and M-S-H

    International Nuclear Information System (INIS)

    Roosz, Cedric

    2016-01-01

    Concrete is one of the most widely used building materials in the world. Durability, mechanical and chemical properties have made it a material of choice in storage concepts proposed by the French National Agency for Radioactive Waste Management (Andra), including the achievement of retaining structures, cell plugs, massive supports or conditioning waste. The study of the stability of the constituent phases of cementitious materials is needed in view of the planned quantities and the durability of the structures, and must consider (i) temperature ranges suitable for cement matrices containment in contact with exothermic waste (25-80 deg. C), and (ii) a representative time scale of the lifetime of the storage. The Andra ThermoChimie project therefore aims to develop a consistent thermodynamic database, to model the chemical evolution of cement materials in the environment of radioactive waste. However, in the present state, the database offers only thermodynamic data of cementitious crystalline phases, as well as a limited data set of three different chemical compositions for nano-crystalline C-S-H. This does not allow to reproduce the degradation of cementitious materials, or model the degradation of the new formulations, such as 'Low pH' concretes. The objective is therefore to acquire a thermodynamic complementary data set on phases such as C-S-H (Calcium Silicate Hydrates) C-A-S-H (Calcium Aluminate Silicate Hydrates) and M-S-H (Magnesium Silicate Hydrates), to complete the ThermoChimie database. This study is based on experimental, analytical and digital work, in order to obtain a set of thermodynamic data (Δ f G 0 , Δ f H 0 , Cp(T), S 0 ) sufficiently representative of the chemical variability of these phases. Finally, this set of data allows the development of a thermodynamic predictive model in extended spaces of compositions and temperatures. Development of this predictive model requires (i) The acquisition of thermodynamic properties on

  12. Coupling two-phase fluid flow with two-phase darcy flow in anisotropic porous media

    KAUST Repository

    Chen, J.; Sun, S.; Chen, Z.

    2014-01-01

    in the free fluid region and the two-phase Darcy law in the anisotropic porous medium region. A Robin-Robin domain decomposition method is used for the coupled Navier-Stokes and Darcy system with the generalized Beavers-Joseph-Saffman condition

  13. Electron excitation cross sections for the 2s(2)2p(3)4S(O) -- 2s(2)2p(3)2D(O) (forbidden) and 4S(O) -- 2s2p(4) 4P (resonance) transitions in O II

    Science.gov (United States)

    Zuo, M.; Smith, Steven J.; Chutjian, A.; Williams, I. D.; Tayal, S. S.; Mclaughlin, Brendan M.

    1995-01-01

    Experimental and theoretical excitation cross sections are reported for the first forbidden transition 4S(O) -- 2S(2)2p(3) 2D(O) (lambda-lambda 3726, 3729) and the first allowed (resonance) transition 4S(O) -- 2s2p(4) 4P(lambda-833) in O II. Use is made of electron energy loss and merged-beams methods. The electron energy range covered is 3.33 (threshold) to 15 eV for the S -- D transition, and 14.9 (threshold) to 40 eV for the S -- P transition. Care was taken to assess and minimize the metastable fraction of the O II beam. An electron mirror was designed and tested to reflect inelastically backscattered electrons into the forward direction to account for the full range of polar scattering angles. Comparisons are made between present experiments and 11-state R-matrix calculations. Calculations are also presented for the 4S(O) -- 2s(2)2p(3)2P(O) (lambda-2470) transition.

  14. Method and apparatus for monitoring two-phase flow. [PWR

    Science.gov (United States)

    Sheppard, J.D.; Tong, L.S.

    1975-12-19

    A method and apparatus for monitoring two-phase flow is provided that is particularly related to the monitoring of transient two-phase (liquid-vapor) flow rates such as may occur during a pressurized water reactor core blow-down. The present invention essentially comprises the use of flanged wire screens or similar devices, such as perforated plates, to produce certain desirable effects in the flow regime for monitoring purposes. One desirable effect is a measurable and reproducible pressure drop across the screen. The pressure drop can be characterized for various known flow rates and then used to monitor nonhomogeneous flow regimes. Another useful effect of the use of screens or plates in nonhomogeneous flow is that such apparatus tends to create a uniformly dispersed flow regime in the immediate downstream vicinity. This is a desirable effect because it usually increases the accuracy of flow rate measurements determined by conventional methods.

  15. Three-dimensional numerical modeling of turbulent single-phase and two-phase flow in curved pipes

    International Nuclear Information System (INIS)

    Xin, R.C.; Dong, Z.F.; Ebadian, M.A.

    1996-01-01

    In this study, three-dimensional single-phase and two-phase flows in curved pipes have been investigated numerically. Two different pipe configurations were computed. When the results of the single-phase flow simulation were compared with the experimental data, a fairly good agreement was achieved. A flow-developing process has been suggested in single-phase flow, in which the turbulence is stronger near the outer tube wall than near the inner tube wall. For two-phase flow, the Eulerian multiphase model was used to simulate the phase distribution of a three-dimensional gas-liquid bubble flow in curved pipe. The RNG/κ-ε turbulence model was used to determine the turbulence field. An inlet gas void fraction of 5 percent was simulated. The gas phase effects on the liquid phase flow velocity have been examined by comparing the results of single-phase flow and two-phase flow. The findings show that for the downward flow in the U bend, the gas concentrates at the inner portion of the cross section at φ = π/18 - π/6 in most cases. The results of the phase distribution simulation are compared to experimental observations qualitatively and topologically

  16. Numerical simulation for two-phase jet problem

    International Nuclear Information System (INIS)

    Lee, W.H.; Shah, V.L.

    1981-01-01

    A computer program TWOP was developed for obtaining the numerical solutions of three-dimensional, transient, two-phase flow system with nonequilibrium and nonhomogeneous conditions. TWOP employs two-fluid model and a set of the conservation equations formulated by Harlow and Amsden along with their Implicit Multi-Field (IMF) numerical technique that allows all degrees of couplings between the two fields. We have further extended the procedure of Harlow and Amsden by incorporating the implicit couplings of phase transition and interfacial heat transfer terms in the energy equations. Numerical results of two tested problems are presented to demonstrate the capabilities of the TWOP code. The first problem is the separation of vapor and liquid, showing that the code can handle the computational difficulties such as liquid packing and sharp interface phenomena. The second problem is the high pressure two-phase jet impinged on vertical plate, demonstrating the important role of the interfacial mass and momentum exchange

  17. Visual Analysis of Inclusion Dynamics in Two-Phase Flow.

    Science.gov (United States)

    Karch, Grzegorz Karol; Beck, Fabian; Ertl, Moritz; Meister, Christian; Schulte, Kathrin; Weigand, Bernhard; Ertl, Thomas; Sadlo, Filip

    2018-05-01

    In single-phase flow visualization, research focuses on the analysis of vector field properties. In two-phase flow, in contrast, analysis of the phase components is typically of major interest. So far, visualization research of two-phase flow concentrated on proper interface reconstruction and the analysis thereof. In this paper, we present a novel visualization technique that enables the investigation of complex two-phase flow phenomena with respect to the physics of breakup and coalescence of inclusions. On the one hand, we adapt dimensionless quantities for a localized analysis of phase instability and breakup, and provide detailed inspection of breakup dynamics with emphasis on oscillation and its interplay with rotational motion. On the other hand, we present a parametric tightly linked space-time visualization approach for an effective interactive representation of the overall dynamics. We demonstrate the utility of our approach using several two-phase CFD datasets.

  18. Nonlinear analysis of gas-water/oil-water two-phase flow in complex networks

    CERN Document Server

    Gao, Zhong-Ke; Wang, Wen-Xu

    2014-01-01

    Understanding the dynamics of multi-phase flows has been a challenge in the fields of nonlinear dynamics and fluid mechanics. This chapter reviews our work on two-phase flow dynamics in combination with complex network theory. We systematically carried out gas-water/oil-water two-phase flow experiments for measuring the time series of flow signals which is studied in terms of the mapping from time series to complex networks. Three network mapping methods were proposed for the analysis and identification of flow patterns, i.e. Flow Pattern Complex Network (FPCN), Fluid Dynamic Complex Network (FDCN) and Fluid Structure Complex Network (FSCN). Through detecting the community structure of FPCN based on K-means clustering, distinct flow patterns can be successfully distinguished and identified. A number of FDCN’s under different flow conditions were constructed in order to reveal the dynamical characteristics of two-phase flows. The FDCNs exhibit universal power-law degree distributions. The power-law exponent ...

  19. Different rates of DNA replication at early versus late S-phase sections: multiscale modeling of stochastic events related to DNA content/EdU (5-ethynyl-2'deoxyuridine) incorporation distributions.

    Science.gov (United States)

    Li, Biao; Zhao, Hong; Rybak, Paulina; Dobrucki, Jurek W; Darzynkiewicz, Zbigniew; Kimmel, Marek

    2014-09-01

    Mathematical modeling allows relating molecular events to single-cell characteristics assessed by multiparameter cytometry. In the present study we labeled newly synthesized DNA in A549 human lung carcinoma cells with 15-120 min pulses of EdU. All DNA was stained with DAPI and cellular fluorescence was measured by laser scanning cytometry. The frequency of cells in the ascending (left) side of the "horseshoe"-shaped EdU/DAPI bivariate distributions reports the rate of DNA replication at the time of entrance to S phase while their frequency in the descending (right) side is a marker of DNA replication rate at the time of transition from S to G2 phase. To understand the connection between molecular-scale events and scatterplot asymmetry, we developed a multiscale stochastic model, which simulates DNA replication and cell cycle progression of individual cells and produces in silico EdU/DAPI scatterplots. For each S-phase cell the time points at which replication origins are fired are modeled by a non-homogeneous Poisson Process (NHPP). Shifted gamma distributions are assumed for durations of cell cycle phases (G1, S and G2 M), Depending on the rate of DNA synthesis being an increasing or decreasing function, simulated EdU/DAPI bivariate graphs show predominance of cells in left (early-S) or right (late-S) side of the horseshoe distribution. Assuming NHPP rate estimated from independent experiments, simulated EdU/DAPI graphs are nearly indistinguishable from those experimentally observed. This finding proves consistency between the S-phase DNA-replication rate based on molecular-scale analyses, and cell population kinetics ascertained from EdU/DAPI scatterplots and demonstrates that DNA replication rate at entrance to S is relatively slow compared with its rather abrupt termination during S to G2 transition. Our approach opens a possibility of similar modeling to study the effect of anticancer drugs on DNA replication/cell cycle progression and also to quantify other

  20. A Novel Aqueous Two Phase System Composed of Surfactant and Xylitol for the Purification of Lipase from Pumpkin (Cucurbita moschata) Seeds and Recycling of Phase Components.

    Science.gov (United States)

    Amid, Mehrnoush; Manap, Mohd Yazid; Hussin, Muhaini; Mustafa, Shuhaimi

    2015-06-17

    Lipase is one of the more important enzymes used in various industries such as the food, detergent, pharmaceutical, textile, and pulp and paper sectors. A novel aqueous two-phase system composed of surfactant and xylitol was employed for the first time to purify lipase from Cucurbita moschata. The influence of different parameters such as type and concentration of surfactants, and the composition of the surfactant/xylitol mixtures on the partitioning behavior and recovery of lipase was investigated. Moreover, the effect of system pH and crude load on the degree of purification and yield of the purified lipase were studied. The results indicated that the lipase was partitioned into the top surfactant rich phase while the impurities partitioned into the bottom xylitol-rich phase using an aqueous two phase system composed of 24% (w/w) Triton X-100 and 20% (w/w) xylitol, at 56.2% of tie line length (TLL), (TTL is one of the important parameters in this study and it is determined from a bimodal curve in which the tie-line connects two nodes on the bimodal, that represent concentration of phase components in the top and bottom phases) and a crude load of 25% (w/w) at pH 8.0. Recovery and recycling of components was also measured in each successive step process. The enzyme was successfully recovered by the proposed method with a high purification factor of 16.4 and yield of 97.4% while over 97% of the phase components were also recovered and recycled. This study demonstrated that the proposed novel aqueous two phase system method is more efficient and economical than the traditional aqueous two phase system method for the purification and recovery of the valuable enzyme lipase.

  1. A Novel Aqueous Two Phase System Composed of Surfactant and Xylitol for the Purification of Lipase from Pumpkin (Cucurbita moschata Seeds and Recycling of Phase Components

    Directory of Open Access Journals (Sweden)

    Mehrnoush Amid

    2015-06-01

    Full Text Available Lipase is one of the more important enzymes used in various industries such as the food, detergent, pharmaceutical, textile, and pulp and paper sectors. A novel aqueous two-phase system composed of surfactant and xylitol was employed for the first time to purify lipase from Cucurbita moschata. The influence of different parameters such as type and concentration of surfactants, and the composition of the surfactant/xylitol mixtures on the partitioning behavior and recovery of lipase was investigated. Moreover, the effect of system pH and crude load on the degree of purification and yield of the purified lipase were studied. The results indicated that the lipase was partitioned into the top surfactant rich phase while the impurities partitioned into the bottom xylitol-rich phase using an aqueous two phase system composed of 24% (w/w Triton X-100 and 20% (w/w xylitol, at 56.2% of tie line length (TLL, (TTL is one of the important parameters in this study and it is determined from a bimodal curve in which the tie-line connects two nodes on the bimodal, that represent concentration of phase components in the top and bottom phases and a crude load of 25% (w/w at pH 8.0. Recovery and recycling of components was also measured in each successive step process. The enzyme was successfully recovered by the proposed method with a high purification factor of 16.4 and yield of 97.4% while over 97% of the phase components were also recovered and recycled. This study demonstrated that the proposed novel aqueous two phase system method is more efficient and economical than the traditional aqueous two phase system method for the purification and recovery of the valuable enzyme lipase.

  2. Relative transcription of Listeria monocytogenes virulence genes in liver pâtés with varying NaCl content

    DEFF Research Database (Denmark)

    Olesen, Inger; Thorsen, Line; Jespersen, Lene

    2010-01-01

    three liver pâtés with reduced NaCl content of which one also has been supplied with organic acids (Ca-acetate and Ca-lactate). The three strains (EGD-e: reference strain; O57: more NaCl sensitive; 6896: more NaCl tolerant) were selected out of twelve strains based on their growth in BHI broth adjusted......B for both O57 and 6896 were significantly higher when the strains were grown in BHI compared to the standard liver pâté. Reducing the NaCl content of the standard liver pâté did not change relative transcription levels of prfA, inlA, sigB or clpC (except for prfA in O57 and sigB in 6896). However......, the presence of Ca-acetate and Ca-lactate induced relative transcription of the stress response gene, clpC, for all three strains. This study demonstrates that relative microbial gene transcription can be measured in complex food matrices and points to the need for designing experimental set-ups in real food...

  3. One-dimensional transient unequal velocity two-phase flow by the method of characteristics

    International Nuclear Information System (INIS)

    Rasouli, F.

    1981-01-01

    An understanding of two-phase flow is important when one is analyzing the accidental loss of coolant or when analyzing industrial processes. If a pipe in the steam generator of a nuclear reactor breaks, the flow will remain critical (or choked) for almost the entire blowdown. For this reason the knowledge of the two-phase maximum (critical) flow rate is important. A six-equation model--consisting of two continuity equations, two energy equations, a mixture momentum equation, and a constitutive relative velocity equation--is solved numerically by the method of characteristics for one-dimensional, transient, two-phase flow systems. The analysis is also extended to the special case of transient critical flow. The six-equation model is used to study the flow of a nonequilibrium sodium-argon system in a horizontal tube in which the nonequilibrium sodium-argon system in a horizontal tube in which the critical flow condition is at the entrance. A four-equation model is used to study the pressure-pulse propagation rate in an isothermal air-water system, and the results that are found are compared with the experimental data. Proper initial and boundary conditions are obtained for the blowdown problem. The energy and mass exchange relations are evaluated by comparing the model predictions with results of void-fraction and heat-transfer experiments. A simplified two-equation model is obtained for the special case of two incompressible phases. This model is used in the preliminary analysis of batch sedimentation. It is also used to predict the shock formation in the gas-solid fluidized bed

  4. Conceptual plan: Two-Phase Flow Laboratory Program for the Waste Isolation Pilot Plant

    International Nuclear Information System (INIS)

    Howarth, S.M.

    1993-07-01

    The Salado Two-Phase Flow Laboratory Program was established to address concerns regarding two-phase flow properties and to provide WIPP-specific, geologically consistent experimental data to develop more appropriate correlations for Salado rock to replace those currently used in Performance Assessment models. Researchers in Sandia's Fluid Flow and Transport Department originally identified and emphasized the need for laboratory measurements of Salado threshold pressure and relative permeability. The program expanded to include the measurement of capillary pressure, rock compressibility, porosity, and intrinsic permeability and the assessment of core damage. Sensitivity analyses identified the anhydrite interbed layers as the most likely path for the dissipation of waste-generated gas from waste-storage rooms because of their relatively high permeability. Due to this the program will initially focus on the anhydrite interbed material. The program may expand to include similar rock and flow measurements on other WIPP materials including impure halite, pure halite, and backfill and seal materials. This conceptual plan presents the scope, objectives, and historical documentation of the development of the Salado Two-Phase Flow Program through January 1993. Potential laboratory techniques for assessing core damage and measuring porosity, rock compressibility, capillary and threshold pressure, permeability as a function of stress, and relative permeability are discussed. Details of actual test designs, test procedures, and data analysis are not included in this report, but will be included in the Salado Two-Phase Flow Laboratory Program Test Plan pending the results of experimental and other scoping activities in FY93

  5. InP/ZnS nanocrystals: coupling NMR and XPS for fine surface and interface description.

    Science.gov (United States)

    Virieux, Héloïse; Le Troedec, Marianne; Cros-Gagneux, Arnaud; Ojo, Wilfried-Solo; Delpech, Fabien; Nayral, Céline; Martinez, Hervé; Chaudret, Bruno

    2012-12-05

    Advanced (1)H, (13)C, and (31)P solution- and solid-state NMR studies combined with XPS were used to probe, at the molecular scale, the composition (of the core, the shell, and the interface) and the surface chemistry of InP/ZnS core/shell quantum dots prepared via a non-coordinating solvent strategy. The interface between the mismatched InP and ZnS phases is composed of an amorphous mixed oxide phase incorporating InPO(x) (with x = 3 and predominantly 4), In(2)O(3), and InO(y)(OH)(3-2y) (y = 0, 1). Thanks to the analysis of the underlying reaction mechanisms, we demonstrate that the oxidation of the upper part of the InP core is the consequence of oxidative conditions brought by decarboxylative coupling reactions (ketonization). These reactions occur during both the core preparation and the coating process, but according to different mechanisms.

  6. Postmodern Movement and Culture: dividing in into periods and discussing its phases Movimento Pós-Moderno e Cultura: periodizando e discutindo suas fases

    Directory of Open Access Journals (Sweden)

    Rosana Figueiredo Salvi

    2002-11-01

    Full Text Available This research tried to divide into periods the postmodern thought starting from the analysis of transformations, which happened inside the movement itself. So, three fundamental phases were emphasized. The first one is responsible for to formation of the postmodern thought in the area of Languages, Arts and Architecture, specifically. The second one is the phase that involves wide dissemination, migration and great controversies about this movement. Finally, the third phase demonstrates relative maturation of the postmodern movement, whose production of theories take place in several fields of knowledge.Esta pesquisa procurou estabelecer uma periodização do pensamento pós-moderno a partir da análise das transformações ocorridas dentro do próprio movimento. Assim, três fases fundamentais foram destacadas. A primeira é entendida como aquela responsável pela formação do pensamento pós-moderno especificamente nas áreas de letras, artes e arquitetura. A segunda é aquela fase que envolve ampla difusão, migração e grandes polêmicas sobre este movimento. Por fim, a terceira fase demonstra relativo amadurecimento do movimento pós-moderno, cuja produção cada vez mais acentuada de teorias ocorre em variadas áreas do conhecimento.

  7. Sensitivity studies on the multi-sensor conductivity probe measurement technique for two-phase flows

    Energy Technology Data Exchange (ETDEWEB)

    Worosz, Ted [Department of Mechanical and Nuclear Engineering, The Pennsylvania State University, 230 Reber Building, University Park, PA 16802 (United States); Bernard, Matt [The United States Nuclear Regulatory Commission, 11545 Rockville Pike, Rockville, MD 20852 (United States); Kong, Ran; Toptan, Aysenur [Department of Mechanical and Nuclear Engineering, The Pennsylvania State University, 230 Reber Building, University Park, PA 16802 (United States); Kim, Seungjin, E-mail: skim@psu.edu [Department of Mechanical and Nuclear Engineering, The Pennsylvania State University, 230 Reber Building, University Park, PA 16802 (United States); Hoxie, Chris [The United States Nuclear Regulatory Commission, 11545 Rockville Pike, Rockville, MD 20852 (United States)

    2016-12-15

    Highlights: • Revised conductivity probe circuit to eliminate signal “ghosting” among sensors. • Higher sampling frequencies suggested for bubble number frequency and a{sub i} measurements. • Two-phase parameter sensitivity to measurement duration and bubble number investigated. • Sensors parallel to pipe wall recommended for symmetric bubble velocity measurements. • Sensor separation distance ratio (s/d) greater than four minimizes bubble velocity error. - Abstract: The objective of this study is to advance the local multi-sensor conductivity probe measurement technique through systematic investigation into several practical aspects of a conductivity probe measurement system. Firstly, signal “ghosting” among probe sensors is found to cause artificially high bubble velocity measurements and low interfacial area concentration (a{sub i}) measurements that depend on sampling frequency and sensor impedance. A revised electrical circuit is suggested to eliminate this artificial variability. Secondly, the sensitivity of the probe measurements to sampling frequency is investigated in 13 two-phase flow conditions with superficial liquid and gas velocities ranging from 1.00–5.00 m/s and 0.17–2.0 m/s, respectively. With increasing gas flow rate, higher sampling frequencies, greater than 100 kHz in some cases, are required to adequately capture the bubble number frequency and a{sub i} measurements. This trend is due to the increase in gas velocity and the transition to the slug flow regime. Thirdly, the sensitivity of the probe measurements to the measurement duration as well as the sample number is investigated for the same flow conditions. Measurements of both group-I (spherical/distorted) and group-II (cap/slug/churn-turbulent) bubbles are found to be relatively insensitive to both the measurement duration and the number of bubbles, as long as the measurements are made for a duration long enough to capture a collection of samples characteristic to a

  8. Debris bed coolability using a 3-D two phase model in a porous medium

    Energy Technology Data Exchange (ETDEWEB)

    Bechaud, C.; Duval, F.; Fichot, F. [CEA Cadarache, Inst. de Protection et de Surete Nucleaire13 - Saint-Paul-lez-Durance (France); Quintard, M. [Institut de Mecanique des Fluides de Toulouse, 31 (France); Parent, M. [CEA Grenoble, Dept. de Thermohydraulique et de Physique, 38 (France)

    2001-07-01

    During a severe nuclear accident, a part of the molten corium resulting from the core degradation may relocate in the lower plenum of the reactor vessel. In order to predict the safety margin of the reactor under such conditions, the coolability of this porous heat-generating medium is evaluated in this study and compared with other investigations. In this work, conservation equations derived for debris beds are implemented in the three dimensional thermal-hydraulic module of the CATHARE code. The coolant flow is a two phase flow with phase change. The momentum balance equation for each fluid phase is an extension of Darcy's law. This extension takes into account the capillary effects between the two phases, the relative permeabilities and passabilities of each phase, the interfacial drag force between liquid and gas, and the porous bed configuration (porosity, particle diameter,... ). The model developed is three-dimensional which is important to better predict the flow in configuration such as counter-current flow or to emphasize preferential ways induced by porous geometry. The energy balance equations of the three phases (liquid, gas and solid phase) are obtained by a volume averaging process of the local conservation equations. In this method, the local thermal non-equilibrium between the three phases is considered and the heat exchanges, the phase change rate as well as the thermal dispersion coefficients are calculated as a function of the local geometry of the porous medium. Such a method allows the numerical estimation of these thermal properties which are very difficult to determine experimentally. This feature is a great advantage of this approach. After a brief description of the thermal-hydraulic model, one-dimensional predictions of critical dryout fluxes are presented and compared with results from the literature. Reasonable agreement is obtained. Then a two-dimensional calculation is presented and shows the influence of the porous medium

  9. Expression of P-glycoprotein, multidrug resistance-associated protein, glutathione-S-transferase pi and p53 in canine transmissible venereal tumor

    Directory of Open Access Journals (Sweden)

    Daniel G. Gerardi

    2014-01-01

    Full Text Available The overexpression of proteins P-glycoprotein (P-gp, multidrug resistance-associated protein (MRP1, mutant p53, and the enzyme glutathione-S-transferase (GSTpi are related to resistance to chemotherapy in neoplasms. This study evaluated the expression of these markers by immunohistochemistry in two groups of canine TVT, without history of prior chemotherapy (TVT1, n=9 and in TVTs presented unsatisfactory clinical response to vincristine sulfate (TVT2, n=5. The percentage of specimens positively stained for P-gp, MRP1, GSTpi and p53 were, respectively 88.8%, 0%, 44.5% and 22.2% in TVT1 and 80%, 0%, 80% and 0% in TVT2. In TVT1, one specimen presented positive expression for three markers and four specimens for two markers. In TVT2, three specimens expressed P-gp and GSTpi. In conclusion, the canine TVTs studied expressed the four markers evaluated, but just P-gp and GSTpi were significantly expressed, mainly at cytoplasm and cytoplasm and nuclei, respectively, either before chemotherapy as after vincristine sulfate exposure. Future studies are needed to demonstrate the function of these two markers in conferring multidrug resistance (MDR or predict the response to chemotherapy in canine TVT.

  10. Experimental study on liquid velocity in upward and downward two-phase flows

    International Nuclear Information System (INIS)

    Sun, X.; Paranjape, S.; Kim, S.; Ozar, B.; Ishii, M.

    2003-01-01

    Local characteristics of the liquid phase in upward and downward air-water two-phase flows were experimentally investigated in a 50.8-mm inner-diameter round pipe. An integral Laser Doppler Anemometry (LDA) system was used to measure the axial liquid velocity and its fluctuations. No effect of the flow direction on the liquid velocity radial profile was observed in single-phase liquid benchmark experiments. Local multi-sensor conductivity probes were used to measure the radial profiles of the bubble velocity and the void fraction. The measurement results in the upward and downward two-phase flows are compared and discussed. The results in the downward flow demonstrated that the presence of the bubbles tended to flatten the liquid velocity radial profile, and the maximum liquid velocity could occur off the pipe centerline, in particular at relatively low flow rates. However, the maximum liquid velocity always occurred at the pipe center in the upward flow. Also, noticeable turbulence enhancement due to the bubbles in the two-phase flows was observed in the current experimental flow conditions. Furthermore, the distribution parameter and the void weighted area-averaged drift velocity were obtained based on the definitions

  11. Fluid dynamics of cryogenic two-phase flows

    International Nuclear Information System (INIS)

    Verfondern, K.; Jahn, W.

    2004-01-01

    The objective of this study was to examine the flow behavior of a methane hydrate/methane-liquid hydrogen dispersed two-phase fluid through a given design of a moderator chamber for the ESS target system. The calculations under simplified conditions, e.g., taking no account of heat input from outside, have shown that the computer code used, CFX, was able to simulate the behavior of the two-phase flow through the moderator chamber, producing reasonable results up to a certain level of the solid phase fraction, that allowed a continuous flow process through the chamber. Inlet flows with larger solid phase fractions than 40 vol% were found to be a ''problem'' for the computer code. From the computer runs based on fractions between 20 and 40 vol%, it was observed that with increasing solid phase fraction at the inlet, the resulting flow pattern revealed a strong tendency for blockage within the chamber, supported by the ''heavy weight'' of the pellets compared to the carrying liquid. Locations which are prone to the development of such uneven flow behavior are the areas around the turning points in the semispheres and near the exit of the moderator. The considered moderator chamber with horizontal inlet and outlet flow for a solid-liquid two-phase fluid does not seem to be an appropriate design. (orig.)

  12. Mik1 levels accumulate in S phase and may mediate an intrinsic link between S phase and mitosis

    DEFF Research Database (Denmark)

    Christensen, P U; Bentley, N J; Martinho, R G

    2000-01-01

    is independent of the Rad3- and Cds1-dependent checkpoint controls. In response to perturbed S phase, Rad3-Cds1 checkpoint controls are required to maintain high levels of Mik1, probably indirectly by extending the S phase period, where Mik1 is stable. In addition, we find that Mik1 protein can be moderately...

  13. Summary on experimental methods for statistical transient analysis of two-phase gas-liquid flow

    International Nuclear Information System (INIS)

    Delhaye, J.M.; Jones, O.C. Jr.

    1976-06-01

    Much work has been done in the study of two-phase gas-liquid flows. Although it has been recognized superficially that such flows are not homogeneous in general, little attention has been paid to the inherent discreteness of the two-phase systems. Only relatively recently have fluctuating characteristics of two-phase flows been studied in detail. As a result, new experimental devices and techniques have been developed for use in measuring quantities previously ignored. This report reviews and summarizes most of these methods in an effort to emphasize the importance of the fluctuating nature of these flows and as a guide to further research in this field

  14. Binge drinking in alcohol-preferring sP rats at the end of the nocturnal period.

    Science.gov (United States)

    Colombo, Giancarlo; Maccioni, Paola; Acciaro, Carla; Lobina, Carla; Loi, Barbara; Zaru, Alessandro; Carai, Mauro A M; Gessa, Gian Luigi

    2014-05-01

    Sardinian alcohol-preferring (sP) rats have been selectively bred for high alcohol preference and consumption using the standard 2-bottle "alcohol (10%, v/v) vs. water" choice regimen with unlimited access; under this regimen, sP rats daily consume 6-7 g/kg alcohol. The present study assessed a new paradigm of alcohol intake in which sP rats were exposed to the 4-bottle "alcohol (10%, 20%, and 30%, v/v) vs. water" choice regimen during one of the 12 h of the dark phase of the daily light/dark cycle; the time of alcohol exposure was changed daily in a semi-random order and was unpredictable to rats. Alcohol intake was highly positively correlated with the time of the drinking session and averaged approximately 2 g/kg when the drinking session occurred during the 12th hour of the dark phase. Alcohol drinking during the 12th hour of the dark phase resulted in (a) blood alcohol levels averaging approximately 100 mg% and (b) severe signs of alcohol intoxication (e.g., impaired performance at a Rota-Rod task). The results of a series of additional experiments indicate that (a) both singular aspects of this paradigm (i.e., unpredictability of alcohol exposure and concurrent availability of multiple alcohol concentrations) contributed to this high alcohol intake, (b) alcohol intake followed a circadian rhythm, as it decreased progressively over the first 3 h of the light phase and then maintained constant levels until the beginning of the dark phase, and (c) sensitivity to time schedule was specific to alcohol, as it did not generalize to a highly palatable chocolate-flavored beverage. These results demonstrate that unpredictable, limited access to multiple alcohol concentrations may result in exceptionally high intakes of alcohol in sP rats, modeling - to some extent - human binge drinking. A progressively increasing emotional "distress" associated to rats' expectation of alcohol might be the neurobehavioral basis of this drinking behavior. Copyright © 2014 Elsevier

  15. Aqueous two-phase system purification for superoxide dismutase induced by menadione from Phanerochaete chrysosporium.

    Science.gov (United States)

    Kavakcıoğlu, Berna; Tongul, Burcu; Tarhan, Leman

    2017-03-01

    In the present work, the partitioning behavior of menadione-induced superoxide dismutase (SOD; EC 1.15.1.1), an antioxidant enzyme that has various applications in the medical and cosmetic industries, from the white rot fungus Phanerochaete chrysosporium has been characterized on different types of aqueous two-phase systems (ATPSs) (poly(ethylene glycol)/polypropylene glycol (PEG/PPG)-dextran, PEG-salt and PPG-salt). PEG-salt combinations were found most optimal systems for the purification of SOD. The best partition conditions were found using the PEG-3350 24% and K 2 HPO 4 5% (w/w) with pH 7.0 at 25 °C. The partition coefficient of total SOD activity and total protein concentration observed in this system were 0.17 and 6.65, respectively, with the recovery percentage as 78.90% in the bottom phase and 13.17% in the top phase. The highest purification fold for SOD from P. chrysosporium was found as 6.04 in the bottom phase of PEG 3350%24 - K 2 HPO 4 %5 (w/w) system with pH 7.0. SOD purified from P. chrysosporium was determined to be a homodimer in its native state with a molecular weight of 60  ± 4 kDa. Consequently, simple and only one step PEG-salt ATPS system was developed for SOD purification from P. chrysosporium.

  16. Location of Heitz's Zerstaeubungsstadium (Dispersion phase) in the mitotic cycle of Phaseolus coccineus and the concept of angiosperm endomitosis

    Energy Technology Data Exchange (ETDEWEB)

    Cavallini, A.; Cionini, P.G.; D' Amato, F. (Pisa Univ. (Italy). Inst. di Genetica)

    1981-01-01

    DNA microdensitometry and autoradiography after treatment with /sup 3/H-thymidine were used to study the phase of dispersion of chromocenters (Z phase) in parallel with chromocentric nuclei in Phaseolus coccineus. In all materials studied, two types of chromocentric nuclei were present. In radicle apices of dry seeds, two classes of nuclear DNA contents were measured, 2 C (G/sub 1/) and 4 C (G/sub 2/). The 2 C DNA class comprised all chromocentric type I nuclei, the 4 C class included Z phases and chromocentric type II nuclei. The 4 C (G/sub 2/) condition of Z phases implies that Z phases maintain their nuclear structure for some time after the end of DNA replication. Shoot apices also contain 2 C (G/sub 1/) and 4 C (G/sub 2/) nuclei but 4 C nuclei (Z phases and chromocentric type II nuclei) are rare. In seedling root apices, Z phases are from 1.02 to 4.08 times as frequent as prophases. This excludes that Z phase as a very early prophase. DNA microdensitometry shows that the chromocentric type I includes 2 C (G/sub 1/) nuclei in the first part of the S phase, Z phases include 4 C (G/sub 2/) nuclei and nuclei in the last stage of the S phase and chromocentric type II includes mainly 4 C (G/sub 2/) nuclei and nuclei in the second part of S. After 90 minutes of treatment with /sup 3/H-thymidine all Z phase nuclei are labeled. This result and the microdensitometric data demonstrate unequivocally that Z phase is located at the end of S. The present results and those of previous authors on Z phase are discussed in relation to Geitler's concept of Angiosperm endomitosis. It is concluded that the term 'Angiosperm endomitosis' must be abandoned and substituted by the term 'chromosome endoreduplication'.

  17. S P Sen Gupta

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. S P Sen Gupta. Articles written in Bulletin of Materials Science. Volume 24 Issue 2 April 2001 pp 173-180. Particle fracture and plastic deformation in vanadium pentoxide powders induced by high energy vibrational ball-mill · Partha Chatterjee S P Sen Gupta Suchitra Sen.

  18. High resolution emission Fourier transform infrared spectra of the 4p-5s and 5p-6s bands of ArH.

    Science.gov (United States)

    Baskakov, O I; Civis, S; Kawaguchi, K

    2005-03-15

    In the 2500-8500 cm(-1) region several strong emission bands of (40)ArH were observed by Fourier transform spectroscopy through a dc glow discharge in a mixture of argon and hydrogen. Rotational-electronic transitions of the two previously unstudied 4p-5s and 5p-6s,v = 0-0, bands of (40)ArH were measured and assigned in the 6060 and 3770 cm(-1) regions, respectively. A simultaneous fit of the emission transitions of the 4p-5s and 5p-6s bands and an extended set of transitions of the 6s-4p band observed by Dabrowski, Tokaryk, and Watson [J. Mol. Spectrosc. 189, 95 (1998)] and remeasured in the present work yielded consistent values of the spectroscopic parameters of the electronic states under investigation. In the branch of the 4p-5s band with transitions of type (Q)Q(f(3)e) we observed a narrowing in the linewidths with increasing rotational quantum number N. The rotational dependence of the linewidth is caused by predissociation of the 5s state by the repulsive ground 4s state through homogeneous coupling and changes in overlap integrals of the vibrational wave functions with the rotational level. Analysis was based on the Fermi's golden rule approximation model. In the 4p-5s band region a vibrational sequence ofv(')-v(")=1-1, 2-2, and 3-3 were recorded and a number of transitions belonging to the strongest (Q)Q(f(3)e) form branch of the 1-1 band were analyzed.

  19. Role of polyamines at the G1/S boundary and G2/M phase of the cell cycle.

    Science.gov (United States)

    Yamashita, Tomoko; Nishimura, Kazuhiro; Saiki, Ryotaro; Okudaira, Hiroyuki; Tome, Mayuko; Higashi, Kyohei; Nakamura, Mizuho; Terui, Yusuke; Fujiwara, Kunio; Kashiwagi, Keiko; Igarashi, Kazuei

    2013-06-01

    The role of polyamines at the G1/S boundary and in the G2/M phase of the cell cycle was studied using synchronized HeLa cells treated with thymidine or with thymidine and aphidicolin. Synchronized cells were cultured in the absence or presence of α-difluoromethylornithine (DFMO), an inhibitor of ornithine decarboxylase, plus ethylglyoxal bis(guanylhydrazone) (EGBG), an inhibitor of S-adenosylmethionine decarboxylase. When polyamine content was reduced by treatment with DFMO and EGBG, the transition from G1 to S phase was delayed. In parallel, the level of p27(Kip1) was greatly increased, so its mechanism was studied in detail. Synthesis of p27(Kip1) was stimulated at the level of translation by a decrease in polyamine levels, because of the existence of long 5'-untranslated region (5'-UTR) in p27(Kip1) mRNA. Similarly, the transition from the G2/M to the G1 phase was delayed by a reduction in polyamine levels. In parallel, the number of multinucleate cells increased by 3-fold. This was parallel with the inhibition of cytokinesis due to an unusual distribution of actin and α-tubulin at the M phase. Since an association of polyamines with chromosomes was not observed by immunofluorescence microscopy at the M phase, polyamines may have only a minor role in structural changes of chromosomes at the M phase. In general, the involvement of polyamines at the G2/M phase was smaller than that at the G1/S boundary. Copyright © 2013 Elsevier Ltd. All rights reserved.

  20. A phase 2 consortium (P2C) trial of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) for advanced adenocarcinoma of the pancreas

    Science.gov (United States)

    Attia, Steven; Kolesar, Jill; Mahoney, Michelle R.; Pitot, Henry C.; Laheru, Daniel; Heun, James; Huang, Wei; Eickhoff, Jens; Erlichman, Charles

    2015-01-01

    Summary 3-Aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP, Triapine®) is a novel small molecule inhibitor of ribonucleotide reductase (RR) with clinical signs of activity in pancreatic cancer. Therefore, the Phase 2 Consortium (P2C) initiated a trial (two single stage studies with planned interim analysis) of 3-AP at 96 mg/m2 intravenously days 1–4 and 15–18 of a 28-day cycle in both chemotherapy-naive and gemcitabine-refractory (GR) patients with advanced pancreatic cancer. The primary endpoint was survival at six months (chemotherapy-naive) and four months (GR). Secondary endpoints were toxicity, response, overall survival, time to progression and mechanistic studies. Fifteen patients were enrolled including one chemotherapy-naïve and 14 GR. The chemotherapy-naïve patient progressed during cycle 1 with grade 3 and 4 toxicities. Of 14 GR patients, seven received two cycles, six received one cycle and one received eight cycles. Progression precluded further treatment in 11 GR patients. Additionally, one died of an ileus in cycle 1 considered related to treatment and two stopped treatment due to toxicity. Five GR patients had grade 4 toxicities possibly related to 3-AP and six GR patients had grade 3 fatigue. Toxicities and lack of meaningful clinical benefit prompted early study closure. Four-month survival in GR patients was 21% (95% CI: 8–58%). Correlative studies confirmed that 3-AP increased the percentage of S-phase buccal mucosal cells, the presence of multidrug resistance gene polymorphisms appeared to predict leukopenia, and baseline pancreatic tumor RR M2 expression was low relative to other tumors treated with 3-AP. In conclusion, this regimen appears inactive against predominantly GR pancreatic cancer. RR M2 protein may not have a critical role in the malignant potential of pancreatic cancer. PMID:18278438