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Sample records for two-loop effective potential

  1. Two Loop Effective Kähler Potential

    CERN Document Server

    Nyawelo, T S; Nyawelo, Tino S.; Nibbelink, Stefan Groot

    2007-01-01

    In this talk we study the renormalization of the effective Kaehler potential at one and two loops for general four dimensional (non--renormalizable) N=1 supersymmetric theories described by arbitrary Kaehler potential, superpotential and gauge kinetic function. We consider the Wess-Zumino model as an example.

  2. Two loop effective Kähler potential of (non-)renormalizable supersymmetric models

    CERN Document Server

    Nibbelink, S G; Nibbelink, Stefan Groot; Nyawelo, Tino S.

    2006-01-01

    We perform a supergraph computation of the effective Kaehler potential at one and two loops for general four dimensional N=1 supersymmetric theories described by arbitrary Kaehler potential, superpotential and gauge kinetic function. We only insist on gauge invariance of the Kaehler potential and the superpotential as we heavily rely on its consequences in the quantum theory. However, we do not require gauge invariance for the gauge kinetic functions, so that our results can also be applied to anomalous theories that involve the Green-Schwarz mechanism. We illustrate our two loop results by considering a few simple models: the (non-)renormalizable Wess-Zumino model and Super Quantum Electrodynamics.

  3. Two-loop scale-invariant scalar potential and quantum effective operators

    Energy Technology Data Exchange (ETDEWEB)

    Ghilencea, D.M. [National Institute of Physics and Nuclear Engineering (IFIN-HH), Theoretical Physics Department, Bucharest (Romania); CERN, Theory Division, Geneva 23 (Switzerland); Lalak, Z.; Olszewski, P. [University of Warsaw, Faculty of Physics, Institute of Theoretical Physics, Warsaw (Poland)

    2016-12-15

    Spontaneous breaking of quantum scale invariance may provide a solution to the hierarchy and cosmological constant problems. In a scale-invariant regularization, we compute the two-loop potential of a Higgs-like scalar φ in theories in which scale symmetry is broken only spontaneously by the dilaton (σ). Its VEV left angle σ right angle generates the DR subtraction scale (μ ∝ left angle σ right angle), which avoids the explicit scale symmetry breaking by traditional regularizations (where μ = fixed scale). The two-loop potential contains effective operators of non-polynomial nature as well as new corrections, beyond those obtained with explicit breaking (μ = fixed scale). These operators have the form φ{sup 6}/σ{sup 2}, φ{sup 8}/σ{sup 4}, etc., which generate an infinite series of higher dimensional polynomial operators upon expansion about left angle σ right angle >> left angle φ right angle, where such hierarchy is arranged by one initial, classical tuning. These operators emerge at the quantum level from evanescent interactions (∝ ε) between σ and φ that vanish in d = 4 but are required by classical scale invariance in d = 4 - 2ε. The Callan-Symanzik equation of the two-loop potential is respected and the two-loop beta functions of the couplings differ from those of the same theory regularized with μ = fixed scale. Therefore the running of the couplings enables one to distinguish between spontaneous and explicit scale symmetry breaking. (orig.)

  4. Two-loop scale-invariant scalar potential and quantum effective operators

    CERN Document Server

    Ghilencea, D.M.

    2016-01-01

    Spontaneous breaking of quantum scale invariance may provide a solution to the hierarchy and cosmological constant problems. In a scale-invariant regularization, we compute the two-loop potential of a higgs-like scalar $\\phi$ in theories in which scale symmetry is broken only spontaneously by the dilaton ($\\sigma$). Its vev $\\langle\\sigma\\rangle$ generates the DR subtraction scale ($\\mu\\sim\\langle\\sigma\\rangle$), which avoids the explicit scale symmetry breaking by traditional regularizations (where $\\mu$=fixed scale). The two-loop potential contains effective operators of non-polynomial nature as well as new corrections, beyond those obtained with explicit breaking ($\\mu$=fixed scale). These operators have the form: $\\phi^6/\\sigma^2$, $\\phi^8/\\sigma^4$, etc, which generate an infinite series of higher dimensional polynomial operators upon expansion about $\\langle\\sigma\\rangle\\gg \\langle\\phi\\rangle$, where such hierarchy is arranged by {\\it one} initial, classical tuning. These operators emerge at the quantum...

  5. The Two-Loop Finite-Temperature Effective Potential of the MSSM and Baryogenesis

    CERN Document Server

    Losada, M

    1999-01-01

    We construct an effective three dimensional theory for the MSSM at high temperatures in the limit of large-$m_{A}$. We analyse the two-loop effective potential of the 3D theory for the case of a light right handed stop to determine the precise region in the $m_{h}$-$m_{\\tilde{t}_{R}}$ plane for which the sphaleron constraint for preservation of the baryon asymmetry is satisfied. We also compare with results previously obtained usind 3D and 4D calculations of the effective potential. A two-stage phase transition still persists for a small range of values of $m_{\\tilde{t}_{R}}$. The allowed region requires a value of $m_{\\tilde{t}_{R}} \\lsi m_{t}$ and $m_{h} \\lsi 100$ (110) GeV for $m_{Q} = 300$ GeV (1 TeV).

  6. Effective Two-loop Thermodynamic Potential with Fermions in the real-time formalism of thermal field theory

    CERN Document Server

    Xin, W; Xin, Wang; Jiarong, Li

    2000-01-01

    Within the real-time formalism (RTF) of thermal field theory,we apply the hard thermal loop (HTL) resummation technique to calculating effective two-loop thermodynamic potential in quark-gluon plasma (QGP) and its renormalization. The result with collective effects is obtained, which is valid for an arbitrary number of quark flavors with masses.

  7. Two-loop dimensional reduction and effective potential without temperature expansions

    OpenAIRE

    M. Laine; Losada, M.

    2000-01-01

    In many extensions of the Standard Model, finite temperature computations are complicated by a hierarchy of zero temperature mass scales, in addition to the usual thermal mass scales. We extend the standard thermal resummations to such a situation, and discuss the 2-loop computations of the Higgs effective potential, and an effective 3d field theory for the electroweak phase transition, without carrying out high or low temperature expansions for the heavy masses. We also estimate the accuracy...

  8. Two-loop dimensional reduction and effective potential without temperature expansions

    CERN Document Server

    Laine, Mikko

    2000-01-01

    In many extensions of the Standard Model, finite temperature computations are complicated by a hierarchy of zero temperature mass scales, in addition to the usual thermal mass scales. We extend the standard thermal resummations to such a situation, and discuss the 2-loop computations of the Higgs effective potential, and an effective 3d field theory for the electroweak phase transition, without carrying out high or low temperature expansions for the heavy masses. We also estimate the accuracy of the temperature expansions previously used for the MSSM electroweak phase transition in the presence of a heavy left-handed stop. We find that the low temperature limit of dealing with the left-handed stop is accurate up to surprisingly high temperatures.

  9. Two-Loop Gluon Regge Trajectory from Lipatov's Effective Action

    CERN Document Server

    Chachamis, Grigorios; Madrigal, José Daniel; Vera, Agustín Sabio

    2012-01-01

    Lipatov's high-energy effective action is a useful tool for computations in the Regge limit beyond leading order. Recently, a regularisation/subtraction prescription has been proposed that allows to apply this formalism to calculate next-to-leading order corrections in a consistent way. We illustrate this procedure with the computation of the gluon Regge trajectory at two loops.

  10. Broken phase effective potential in the two-loop Phi-derivable approximation and nature of the phase transition in a scalar theory

    CERN Document Server

    Markó, Gergely; Szép, Zsolt

    2012-01-01

    We study the phase transition of a real scalar phi^4 theory in the two-loop Phi-derivable approximation using the imaginary time formalism, extending our previous (analytical) discussion of the Hartree approximation. We combine Fast Fourier Transform algorithms and accelerated Matsubara sums in order to achieve a high accuracy. Our results confirm and complete earlier ones obtained in the real time formalism [1] but which were less accurate due to the integration in Minkowski space and the discretization of the spectral density function. We also provide a complete and explicit discussion of the renormalization of the two-loop Phi-derivable approximation at finite temperature, both in the symmetric and in the broken phase, which was already used in the real-time approach, but never published. Our main result is that the two-loop Phi-derivable approximation suffices to cure the problem of the Hartree approximation regarding the order of the transition: the transition is of the second order type, as expected on ...

  11. The Two-Loop Scale Dependence of the Static QCD Potential including Quark Masses

    Energy Technology Data Exchange (ETDEWEB)

    Brodsky, Stanley J.

    1999-06-14

    The interaction potential V(Q{sup 2}) between static test charges can be used to define an effective charge {alpha}{sub V}(Q{sup 2}) and a physically-based renormalization scheme for quantum chromodynamics and other gauge theories. In this paper we use recent results for the finite-mass fermionic corrections to the heavy-quark potential at two-loops to derive the next-to-leading order term for the Gell Mann-Low function of the V-scheme. The resulting effective number of flavors N{sub F}(Q{sup 2}/m{sup 2}) in the {alpha}{sub V} scheme is determined as a gauge-independent and analytic function of the ratio of the momentum transfer to the quark pole mass. The results give automatic decoupling of heavy quarks and are independent of the renormalization procedure. Commensurate scale relations then provide the next-to-leading order connection between all perturbatively calculable observables to the analytic and gauge-invariant {alpha}{sub V} scheme without any scale ambiguity and a well defined number of active flavors. The inclusion of the finite quark mass effects in the running of the coupling is compared with the standard treatment of finite quark mass effects in the {ovr MS} scheme.

  12. Reformulating the TBA equations for the quark anti-quark potential and their two loop expansion

    Energy Technology Data Exchange (ETDEWEB)

    Bajnok, Zoltán; Balog, János [MTA Lendület Holographic QFT Group, Wigner Research Centre,H-1525 Budapest 114, P.O.B. 49 (Hungary); Correa, Diego H. [Instituto de Física La Plata, CONICET, Universidad Nacional de La Plata, C.C. 67, 1900 La Plata (Argentina); Hegedűs, Árpád [MTA Lendület Holographic QFT Group, Wigner Research Centre,H-1525 Budapest 114, P.O.B. 49 (Hungary); Massolo, Fidel I. Schaposnik [Instituto de Física La Plata, CONICET, Universidad Nacional de La Plata, C.C. 67, 1900 La Plata (Argentina); Tóth, Gábor Zsolt [MTA Lendület Holographic QFT Group, Wigner Research Centre,H-1525 Budapest 114, P.O.B. 49 (Hungary)

    2014-03-11

    The boundary thermodynamic Bethe Ansatz (BTBA) equations introduced in http://dx.doi.org/10.1007/JHEP08(2012)134http://dx.doi.org/10.1007/JHEP10(2013)135 to describe the cusp anomalous dimension contain imaginary chemical potentials and singular boundary fugacities, which make its systematic expansion problematic. We propose an alternative formulation based on real chemical potentials and additional source terms. We expand our equations to double wrapping order and find complete agreement with the direct two-loop gauge theory computation of the cusp anomalous dimension.

  13. Two-loop renormalization of the effective field theory of a static quark

    CERN Document Server

    Broadhurst, D J

    1991-01-01

    We give a recurrence relation for two-loop integrals encountered in the effective field theory of an infinitely heavy quark, Q, interacting with gluons and Nl massless quarks, q, from which we obtain exact two-loop results, in any dimension and covariant gauge, for the propagator of Q and the vertex function of the heavy-light current J = Q Gamma q, at zero q momentum. The anomalous dimension of the Q field agrees with the recent result of Broadhurst, Gray and Schilcher. The anomalous dimension of the current is gamma_J = d log Z_J / d log mu = - alpha_s/pi (1 + (127 + 56 zeta(2) - 10 Nl)/72) alpha_s/pi + O(alpha_s^2)) which gives the new two-loop correction to the result of Voloshin and Shifman.

  14. The Effective Field Theory of Large Scale Structures at two loops

    Energy Technology Data Exchange (ETDEWEB)

    Carrasco, John Joseph M.; Foreman, Simon; Green, Daniel; Senatore, Leonardo, E-mail: jjmc@stanford.edu, E-mail: sfore@stanford.edu, E-mail: drgreen@stanford.edu, E-mail: senatore@stanford.edu [Stanford Institute for Theoretical Physics and Department of Physics, Stanford University, Stanford, CA 94306 (United States)

    2014-07-01

    Large scale structure surveys promise to be the next leading probe of cosmological information. It is therefore crucial to reliably predict their observables. The Effective Field Theory of Large Scale Structures (EFTofLSS) provides a manifestly convergent perturbation theory for the weakly non-linear regime of dark matter, where correlation functions are computed in an expansion of the wavenumber k of a mode over the wavenumber associated with the non-linear scale k{sub NL}. Since most of the information is contained at high wavenumbers, it is necessary to compute higher order corrections to correlation functions. After the one-loop correction to the matter power spectrum, we estimate that the next leading one is the two-loop contribution, which we compute here. At this order in k/k{sub NL}, there is only one counterterm in the EFTofLSS that must be included, though this term contributes both at tree-level and in several one-loop diagrams. We also discuss correlation functions involving the velocity and momentum fields. We find that the EFTofLSS prediction at two loops matches to percent accuracy the non-linear matter power spectrum at redshift zero up to k∼ 0.6 h Mpc{sup −1}, requiring just one unknown coefficient that needs to be fit to observations. Given that Standard Perturbation Theory stops converging at redshift zero at k∼ 0.1 h Mpc{sup −1}, our results demonstrate the possibility of accessing a factor of order 200 more dark matter quasi-linear modes than naively expected. If the remaining observational challenges to accessing these modes can be addressed with similar success, our results show that there is tremendous potential for large scale structure surveys to explore the primordial universe.

  15. The complete two-loop integrated jet thrust distribution in soft-collinear effective theory

    Energy Technology Data Exchange (ETDEWEB)

    von Manteuffel, Andreas; Schabinger, Robert M.; Zhu, Hua Xing

    2014-03-01

    In this work, we complete the calculation of the soft part of the two-loop integrated jet thrust distribution in e+e- annihilation. This jet mass observable is based on the thrust cone jet algorithm, which involves a veto scale for out-of-jet radiation. The previously uncomputed part of our result depends in a complicated way on the jet cone size, r, and at intermediate stages of the calculation we actually encounter a new class of multiple polylogarithms. We employ an extension of the coproduct calculus to systematically exploit functional relations and represent our results concisely. In contrast to the individual contributions, the sum of all global terms can be expressed in terms of classical polylogarithms. Our explicit two-loop calculation enables us to clarify the small r picture discussed in earlier work. In particular, we show that the resummation of the logarithms of r that appear in the previously uncomputed part of the two-loop integrated jet thrust distribution is inextricably linked to the resummation of the non-global logarithms. Furthermore, we find that the logarithms of r which cannot be absorbed into the non-global logarithms in the way advocated in earlier work have coefficients fixed by the two-loop cusp anomalous dimension. We also show that in many cases one can straightforwardly predict potentially large logarithmic contributions to the integrated jet thrust distribution at L loops by making use of analogous contributions to the simpler integrated hemisphere soft function.

  16. Two-loop virtual top-quark effect on Higgs-boson decay to bottom quarks.

    Science.gov (United States)

    Butenschön, Mathias; Fugel, Frank; Kniehl, Bernd A

    2007-02-16

    In most of the mass range encompassed by the limits from the direct search and the electroweak precision tests, the Higgs boson of the standard model preferably decays to bottom quarks. We present, in analytic form, the dominant two-loop electroweak correction, of O(GF2mt4), to the partial width of this decay. It amplifies the familiar enhancement due to the O(GFmt2) one-loop correction by about +16% and thus more than compensates the screening by about -8% through strong-interaction effects of order O(alphasGFmt2).

  17. Electroweak two-loop corrections to the effective weak mixing angle

    Energy Technology Data Exchange (ETDEWEB)

    Awramik, M. [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik]|[Institute of Nuclear Physics, Cracow (Poland); Czakon, M. [Wuerzburg Univ. (Germany). Inst. fuer Theoretische Physik und Astrophysik]|[Silesia Univ., Katowice (Poland). Dept. of Field Theory and Particle Physics; Freitas, A. [Zuerich Univ. (Switzerland). Inst. fuer Theoretische Physik

    2006-08-15

    Recently exact results for the complete electroweak two-loop contributions to the effective weak mixing angle were published. This paper illustrates the techniques used for this computation, in particular the methods for evaluating the loop diagrams and the proper definition of Z-pole observables at next-to-next -to-leading order. Numerical results are presented in terms of simple parametrization formulae and compared in detail with a previous result of an expansion up to next-to-leading order in the top-quark mass. Finally, an estimate of the remaining theoretical uncertainties from unknown higher-order corrections is given. (Orig.)

  18. Infrared divergences and harmonic anomalies in the two-loop superstring effective action

    CERN Document Server

    Pioline, Boris

    2015-01-01

    We analyze the pertubative contributions to the $D^4 R^4$ and $D^6 R^4$ couplings in the low-energy effective action of type II string theory compactified on a torus $T^d$, with particular emphasis on two-loop corrections. In general, it is necessary to introduce an infrared cut-off $\\Lambda$ to separate local interactions from non-local effects due to the exchange of massless states. We identify the degenerations of the genus-two Riemann surface which are responsible for power-like dependence on $\\Lambda$, and give an explicit prescription for extracting the $\\Lambda$-independent effective couplings. These renormalized couplings are then shown to be eigenmodes of the Laplace operator with respect to the torus moduli, up to computable anomalous source terms arising in the presence of logarithmic divergences, in precise agreement with predictions from U-duality. Our results for the two-loop $D^6 R^4$ contribution also probe essential properties of the Kawazumi-Zhang invariant

  19. Two-loop anomalous dimensions of heavy baryon currents in heavy quark effective theory

    CERN Document Server

    Groote, S; Yakovlev, O I

    1996-01-01

    We present results on the two-loop anomalous dimensions of the heavy baryon HQET currents J=(q^TC\\Gamma\\tau q)\\Gamma'Q with arbitrary Dirac matrices \\Gamma and \\Gamma'. From our general result we obtain the two-loop anomalous dimensions for currents with quantum numbers of the ground state heavy baryons \\Lambda_Q, \\Sigma_Q and \\Sigma_Q^*. As a by-product of our calculation and as an additional check we rederive the known two-loop anomalous dimensions of mesonic scalar, pseudoscalar, vector, axial vector and tensor currents (J=\\bar q\\Gamma q) in massless QCD as well as in HQET.

  20. Two-loop thermodynamics of warm and dense (isospin and baryo-chemical potential) perturbative QCD

    Energy Technology Data Exchange (ETDEWEB)

    Graf, Thorben [Institut fuer Theoretische Physik, Goethe Universitaet, Frankfurt am Main (Germany); Schaffner-Bielich, Juergen [Institut fuer Theoretische Physik, Goethe Universitaet, Frankfurt am Main (Germany); Fraga, Eduardo S. [Instituto de Fisica, Universidade Federal do Rio de Janeiro, Rio de Janeiro (Brazil)

    2014-07-01

    We present a perturbative calculation of the thermodynamical potential of quantum chromodynamics at nonvanishing temperatures for different values of the isospin and baryo-chemical potential. A comparison to recent lattice calculations at nonvanishing isospin is performed and the region of the break-down of the perturbative calculations are delineated. Finally, we study the thermodynamic potential at high chemical potentials and low temperatures where the perturbative scheme should be also applicable.

  1. Matching QCD and heavy-quark effective theory heavy-light currents at two loops and beyond

    Science.gov (United States)

    Broadhurst, D. J.; Grozin, A. G.

    1995-10-01

    Heavy-light QCD currents are matched with heavy-quark effective theory (HQET) currents at two loops and leading order in 1/m. A single formula applies to all current matchings. As a by-product, a master formula for the two-loop anomalous dimension of the QCD current q¯γ[μ1...γμn]q is obtained, yielding a new result for the tensor current. The dependence of matching coefficients on γ5 prescriptions is elucidated. Ratios of QCD matrix elements are obtained, independently of the three-loop anomalous dimension of HQET currents. The two-loop coefficient in f*B/fB =1-2αs(mb)/3π-Kbα2s/π2 +O(α3s,1/mb) is Kb=83/12+4/81π2+2/27π2ln2-1/9ζ(3)-19/54Nl +Δc=6.37+Δc, with Nl=4 light flavors, and a correction Δc=0.18+/-0.01 that takes account of the nonzero ratio mc/mb=0.28+/-0.03. Convergence of the perturbative series is poor: the fastest apparent convergence would entail αs(μ) at μ=370 MeV. ``Naive non-Abelianization'' of large-Nl results, via Nl-->Nl-33/2, gives reasonable approximations to exact two-loop results. All-order results for anomalous dimensions and matching coefficients are obtained at large β0=11=2/3Nl. Consistent cancellation between infrared- and ultraviolet-renormalon ambiguities is demonstrated.

  2. Effective field theory of large scale structure at two loops: The apparent scale dependence of the speed of sound

    Science.gov (United States)

    Baldauf, Tobias; Mercolli, Lorenzo; Zaldarriaga, Matias

    2015-12-01

    We study the effective field theory (EFT) of large-scale structure for cosmic density and momentum fields. We show that the finite part of the two-loop calculation and its counterterms introduces an apparent scale dependence for the leading-order parameter cs2 of the EFT starting at k =0.1 h Mpc-1 . These terms limit the range over which one can trust the one-loop EFT calculation at the 1% level to k z =0 . We construct a well-motivated one-parameter ansatz to fix the relative size of the one- and two-loop counterterms using their high-k sensitivity. Although this one-parameter model is a very restrictive choice for the counterterms, it explains the apparent scale dependence of cs2 seen in simulations. It is also able to capture the scale dependence of the density power spectrum up to k ≈0.3 h Mpc-1 at the 1% level at redshift z =0 . Considering a simple scheme for the resummation of large-scale motions, we find that the two-loop calculation reduces the need for this IR resummation at k <0.2 h Mpc-1 . Finally, we extend our calculation to momentum statistics and show that the same one-parameter model can also describe density-momentum and momentum-momentum statistics.

  3. The Effective Field Theory of Large Scale Structure at Two Loops: the apparent scale dependence of the speed of sound

    CERN Document Server

    Baldauf, Tobias; Zaldarriaga, Matias

    2015-01-01

    We study the Effective Field Theory of Large Scale Structure for cosmic density and momentum fields. We show that the finite part of the two-loop calculation and its counterterms introduce an apparent scale dependence for the leading order parameter $c_\\text{s}^2$ of the EFT starting at k=0.1 h/Mpc. These terms limit the range over which one can trust the one-loop EFT calculation at the 1 % level to k<0.1 h/Mpc at redshift z=0. We construct a well motivated one parameter ansatz to fix the relative size of the one- and two-loop counterterms using their high-k sensitivity. Although this one parameter model is a very restrictive choice for the counterterms, it explains the apparent scale dependence of $c_\\text{s}^2$ seen in simulations. It is also able to capture the scale dependence of the density power spectrum up to k$\\approx$ 0.3 h/Mpc at the 1 % level at redshift $z=0$. Considering a simple scheme for the resummation of large scale motions, we find that the two loop calculation reduces the need for this ...

  4. Testable two-loop radiative neutrino mass model based on an LLQd^cQd^c effective operator

    CERN Document Server

    Angel, Paul W; Rodd, Nicholas L; Schmidt, Michael A; Volkas, Raymond R

    2013-01-01

    A new two-loop radiative Majorana neutrino mass model is constructed from the gauge- invariant effective operator L^i L^j Q^k d^c Q^l d^c \\epsilon_{ik} \\epsilon_{jl} that violates lepton number conservation by two units. The ultraviolet completion features two scalar leptoquark flavors and a color-octet Majorana fermion. We show that there exists a region of parameter space where the neutrino oscillation data can be fitted while simultaneously meeting flavor-violation and collider bounds. The model is testable through lepton flavor-violating processes such as {\\mu} -> e{\\gamma}, {\\mu} -> eee, and {\\mu}N -> eN conversion, as well as collider searches for the scalar leptoquarks and color-octet fermion. We computed and compiled a list of necessary Passarino-Veltman integrals up to boxes in the approximation of vanishing external momenta and made them available as a Mathematica package, denoted as ANT.

  5. The two-loop effective action and some symmetries of the Riemann tensor and the Kalb-Ramond H field

    CERN Document Server

    Ozkurt, S S

    2003-01-01

    Sometimes ago, it has been proposed in a paper by N.Kaloper and K.A.Meissner (\\PR {\\bf D56} (1997) 7940) that if one makes local redefinitions of fields, it does not change the equations of motion (in the redefined fields); however, this comment has not generally been accepted, namely, the redefined fields satisfy different equations of motion. For this reason, the whole action will be written in terms of the zeroth-order field equations in this paper. In this study, we also observe that N.Kaloper and K.A.Meissner's effective action (\\PR {\\bf D56} (1997) 7940)which has a duality symmetry beyond the first loop, can be written in terms of the zeroth-order field equations if the Riemann tensor and the Kalb-Ramond field have some symmetries. For example, K\\"{a}hler manifolds have these symmetries.

  6. Two-loop Bethe-logarithm correction in hydrogenlike atoms.

    Science.gov (United States)

    Pachucki, Krzysztof; Jentschura, Ulrich D

    2003-09-12

    We calculate the two-loop Bethe logarithm correction to atomic energy levels in hydrogenlike systems. The two-loop Bethe logarithm is a low-energy quantum electrodynamic (QED) effect involving multiple summations over virtual excited atomic states. Although much smaller in absolute magnitude than the well-known one-loop Bethe logarithm, the two-loop analog is quite significant when compared to the current experimental accuracy of the 1S-2S transition: It contributes -8.19 and -0.84 kHz for the 1S and the 2S state, respectively. The two-loop Bethe logarithm has been the largest unknown correction to the hydrogen Lamb shift to date. Together with the ongoing measurement of the proton charge radius at the Paul Scherrer Institute, its calculation will bring theoretical and experimental accuracy for the Lamb shift in atomic hydrogen to the level of 10(-7).

  7. Effect of spray system on fission product distribution in containment during a severe accident in a two-loop pressurized water reactor

    Energy Technology Data Exchange (ETDEWEB)

    Dehjourian, Mehdi; Rahgoshay, Mohammad; Jahanfamia, Gholamreza [Dept. of Nuclear Engineering, Science and Research Branch, Islamic Azad University of Tehran, Tehran (Iran, Islamic Republic of); Sayareh, Reza [Faculty of Electrical and Computer Engineering, Kerman Graduate University of Technology, Kerman (Iran, Islamic Republic of); Shirani, Saied [Faculty of Engineering, Shahid Beheshti University, Tehran (Iran, Islamic Republic of)

    2016-08-15

    The containment response during the first 24 hours of a low-pressure severe accident scenario in a nuclear power plant with a two-loop Westinghouse-type pressurized water reactor was simulated with the CONTAIN 2.0 computer code. The accident considered in this study is a large-break loss-of-coolant accident, which is not successfully mitigated by the action of safety systems. The analysis includes pressure and temperature responses, as well as investigation into the influence of spray on the retention of fission products and the prevention of hydrogen combustion in the containment.

  8. Effect of Spray System on Fission Product Distribution in Containment During a Severe Accident in a Two-Loop Pressurized Water Reactor

    Directory of Open Access Journals (Sweden)

    Mehdi Dehjourian

    2016-08-01

    Full Text Available The containment response during the first 24 hours of a low-pressure severe accident scenario in a nuclear power plant with a two-loop Westinghouse-type pressurized water reactor was simulated with the CONTAIN 2.0 computer code. The accident considered in this study is a large-break loss-of-coolant accident, which is not successfully mitigated by the action of safety systems. The analysis includes pressure and temperature responses, as well as investigation into the influence of spray on the retention of fission products and the prevention of hydrogen combustion in the containment.

  9. Off-shell two loop QCD vertices

    CERN Document Server

    Gracey, J A

    2014-01-01

    We calculate the triple gluon, ghost-gluon and quark-gluon vertex functions at two loops in the MSbar scheme in the chiral limit for an arbitrary linear covariant gauge when the external legs are all off-shell.

  10. Two-Loop Threshold Singularities, Unstable Particles and Complex Masses

    CERN Document Server

    Actis, S; Sturm, C; Uccirati, S

    2008-01-01

    The effect of threshold singularities induced by unstable particles on two-loop observables is investigated and it is shown how to cure them working in the complex-mass scheme. The impact on radiative corrections around thresholds is thoroughly analyzed and shown to be relevant for two selected LHC and ILC applications: Higgs production via gluon fusion and decay into two photons at two loops in the Standard Model. Concerning Higgs production, it is essential to understand possible sources of large corrections in addition to the well-known QCD effects. It is shown that NLO electroweak corrections can incongruently reach a 10 % level around the WW vector-boson threshold without a complete implementation of the complex-mass scheme in the two-loop calculation.

  11. Two loop scalar bilinears for inflationary SQED

    Energy Technology Data Exchange (ETDEWEB)

    Prokopec, T [Institute for Theoretical Physics and Spinoza Institute, Utrecht University Leuvenlaan 4, Postbus 80.195, 3508 TD Utrecht (Netherlands); Tsamis, N C [Department of Physics, University of Crete GR-710 03 Heraklion, Hellas (Greece); Woodard, R P [Department of Physics, University of Florida Gainesville, FL 32611 (United States)

    2007-01-07

    We evaluate the one- and two-loop contributions to the expectation values of two coincident and gauge invariant scalar bilinears in the theory of massless, minimally coupled scalar quantum electrodynamics on a locally de Sitter background. One of these bilinears is the product of two covariantly differentiated scalars, the other is the product of two undifferentiated scalars. The computations are done using dimensional regularization and the Schwinger-Keldysh formalism. Our results are in perfect agreement with the stochastic predictions at this order.

  12. Complex-mass renormalization in hadronic EFT: applicability at two-loop order

    CERN Document Server

    Djukanovic, D; Gegelia, J; Krebs, H; Meißner, U -G

    2015-01-01

    We discuss the application of the complex-mass scheme to multi-loop diagrams in hadronic effective field theory by considering as an example a two-loop self-energy diagram. We show that the renormalized two-loop diagram satisfies the power counting.

  13. Complex-mass renormalization in hadronic EFT: Applicability at two-loop order

    Energy Technology Data Exchange (ETDEWEB)

    Djukanovic, D. [University of Mainz, Helmholtz Institute Mainz, Mainz (Germany); Epelbaum, E.; Krebs, H. [Ruhr-Universitaet Bochum, Institut fuer Theoretische Physik II, Bochum (Germany); Gegelia, J. [Forschungszentrum Juelich, Institute for Advanced Simulation, Institut fuer Kernphysik and Juelich Center for Hadron Physics, Juelich (Germany); Tbilisi State University, Tbilisi (Georgia); Meissner, U.G. [Universitaet Bonn, Helmholtz Institut fuer Strahlen- und Kernphysik and Bethe Center for Theoretical Physics, Bonn (Germany); Forschungszentrum Juelich, Institute for Advanced Simulation, Institut fuer Kernphysik and Juelich Center for Hadron Physics, Juelich (Germany)

    2015-08-15

    We discuss the application of the complex-mass scheme to multi-loop diagrams in hadronic effective field theory by considering as an example a two-loop self-energy diagram. We show that the renormalized two-loop diagram satisfies the power counting. (orig.)

  14. Two loop unification of non-SUSY SO(10) GUT with TeV scalars

    Science.gov (United States)

    Brennan, T. Daniel

    2017-03-01

    In this paper we examine gauge coupling unification of the non-SUSY SO(10) grand unified theory proposed by Babu and Mohapatra [Phys. Lett. B 715, 328 (2012), 10.1016/j.physletb.2012.08.006] at the two loop level. This theory breaks down to the standard model in a single step and has the distinguishing feature of TeV nonstandard model scalars. This leads to a plethora of interesting new physics at the TeV scale and the discovery of new particles at the LHC. This model gives rise to testable proton decay, neutron-antineutron oscillations, provides a mechanism for baryogenesis, and contains potential dark matter candidates. In this paper, we compute the two loop beta function and show that this model unifies to two loop order around 1 015 GeV . We then compute the proton lifetime, taking into account threshold effects and show that these effects place it above the Super-Kamiokande limit [K. Abe et al. (Super-Kamiokande Collaboration), Phys. Rev. D 95, 012004 (2017)., 10.1103/PhysRevD.95.012004].

  15. Supersymmetric Wilson loops at two loops

    CERN Document Server

    Bassetto, Antonio; Pucci, Fabrizio; Seminara, Domenico

    2008-01-01

    We study the quantum properties of certain BPS Wilson loops in ${\\cal N}=4$ supersymmetric Yang-Mills theory. They belong to a general family, introduced recently, in which the addition of particular scalar couplings endows generic loops on $S^3$ with a fraction of supersymmetry. When restricted to $S^2$, their quantum average has been further conjectured to be exactly computed by the matrix model governing the zero-instanton sector of YM$_2$ on the sphere. We perform a complete two-loop analysis on a class of cusped Wilson loops lying on a two-dimensional sphere, finding perfect agreement with the conjecture. The perturbative computation reproduces the matrix-model expectation through a highly non-trivial interplay between ladder diagrams and self-energies/vertex contributions, suggesting the existence of a localization procedure.

  16. A note on two-loop superloop

    Science.gov (United States)

    Belitsky, A. V.

    2012-11-01

    We explore the duality between supersymmetric Wilson loop on null polygonal contours in maximally supersymmetric Yang-Mills theory and next-to-maximal helicity violating (NMHV) scattering amplitudes. Earlier analyses demonstrated that the use of a dimensional regulator for ultraviolet divergences, induced due to presence of the cusps on the loop, yields anomalies that break both conformal symmetry and supersymmetry. At one-loop order, these are present only in Grassmann components localized in the vicinity of a single cusp and result in a universal function for any number of sites of the polygon that can be subtracted away in a systematic manner leaving a well-defined supersymmetric remainder dual to corresponding components of the superamplitude. The question remains though whether components which were free from the aforementioned supersymmetric anomaly at leading order of perturbation theory remain so once computed at higher orders. Presently we verify this fact by calculating a particular component of the null polygonal super Wilson loop at two loops restricting the contour kinematics to a two-dimensional subspace. This allows one to perform all computations in a concise analytical form and trace the pattern of cancellations between individual Feynman graphs in a transparent fashion. As a consequence of our consideration we obtain a dual conformally invariant result for the remainder function in agreement with one-loop NMHV amplitudes.

  17. On the two-loop corrections to the Higgs mass in trilinear R-parity violation

    Directory of Open Access Journals (Sweden)

    Herbi K. Dreiner

    2015-03-01

    Full Text Available We study the impact of large trilinear R-parity violating couplings on the lightest CP-even Higgs boson mass in supersymmetric models. We use the publicly available computer codes SARAH and SPheno to compute the leading two-loop corrections. We use the effective potential approach. For not too heavy third generation squarks (m˜≲1 TeV and couplings close to the unitarity bound we find positive corrections up to a few GeV in the Higgs mass.

  18. Deconfinement transition in SU(2) Yang-Mills theory: a two-loop study

    CERN Document Server

    Reinosa, U; Tissier, M; Wschebor, N

    2014-01-01

    In a recent work we have proposed a perturbative approach for the study of the phase transition of pure Yang-Mills theories at finite temperature. This is based on a simple massive extension of background field methods in the Landau-DeWitt gauge, where the gluon mass term is related to the existence of Gribov ambiguities. We have shown that a one-loop calculation of the background field effective potential describes well the phase structure of the SU(2) and SU(3) theories. Here, we present the calculation of the next-to-leading order contribution in perturbation theory for the SU(2) case. In particular, we compute the background field effective potential at two-loop order and the corresponding Polyakov loop, a gauge invariant order parameter of the transition, at one-loop order. We show that the two-loop correction brings the critical temperature closer to its actual value as compared to the previous one-loop result. We also compute the thermodynamic pressure as a function of the temperature and show that two...

  19. On-shell two-loop three-gluon vertex

    CERN Document Server

    Davydychev, A I

    1999-01-01

    The two-loop three-gluon vertex is calculated in an arbitrary covariant gauge, in the limit when two of the gluons are on the mass shell. The corresponding two-loop results for the ghost-gluon vertex are also obtained. It is shown that the results are consistent with the Ward-Slavnov-Taylor identities.

  20. Two-loop corrections to the ρ parameter in Two-Higgs-Doublet models

    Energy Technology Data Exchange (ETDEWEB)

    Hessenberger, Stephan; Hollik, Wolfgang [Max-Planck-Institut fuer Physik (Werner-Heisenberg-Institut), Muenchen (Germany)

    2017-03-15

    Models with two scalar doublets are among the simplest extensions of the Standard Model which fulfill the relation ρ = 1 at lowest order for the ρ parameter as favored by experimental data for electroweak observables allowing only small deviations from unity. Such small deviations Δρ originate exclusively from quantum effects with special sensitivity to mass splittings between different isospin components of fermions and scalars. In this paper the dominant two-loop electroweak corrections to Δρ are calculated in the CP-conserving THDM, resulting from the top-Yukawa coupling and the self-couplings of the Higgs bosons in the gauge-less limit. The on-shell renormalization scheme is applied. With the assumption that one of the CP-even neutral scalars represents the scalar boson observed by the LHC experiments, with standard properties, the two-loop non-standard contributions in Δρ can be separated from the standard ones. These contributions are of particular interest since they increase with mass splittings between non-standard Higgs bosons and can be additionally enhanced by tanβ and λ{sub 5}, an additional free coefficient of the Higgs potential, and can thus modify the one-loop result substantially. Numerical results are given for the dependence on the various non-standard parameters, and the influence on the calculation of electroweak precision observables is discussed. (orig.)

  1. Off-shell two-loop QCD vertices

    Science.gov (United States)

    Gracey, J. A.

    2014-07-01

    We calculate the triple gluon, ghost-gluon and quark-gluon vertex functions at two loops in the MS¯ scheme in the chiral limit for an arbitrary linear covariant gauge when the external legs are all off shell.

  2. The Higgs Mass in the MSSM at two-loop order beyond minimal flavour violation

    CERN Document Server

    Goodsell, Mark D; Staub, Florian

    2015-01-01

    Soft supersymmetry-breaking terms provide a wealth of new potential sources of flavour violation, which lead to very tight constraints from precision experiments. This has posed a challenge to construct flavour models to both explain the structure of the Standard Model Yukawa couplings and how their consequent predictions for patterns in the soft supersymmetry-breaking terms do not violate these constraints. While such models have been studied in great detail, the impact of flavour violating soft terms on the Higgs mass at the two-loop level has been assumed to be small or negligible. In this letter, we show that large flavour violation in the up-squark sector can give a positive or negative shift to the SM-like Higgs of several GeV, without being in conflict with any other observation. We investigate in which regions of the parameter space these effects can be expected.

  3. The Higgs mass in the MSSM at two-loop order beyond minimal flavour violation

    Science.gov (United States)

    Goodsell, Mark D.; Nickel, Kilian; Staub, Florian

    2016-07-01

    Soft supersymmetry-breaking terms provide a wealth of new potential sources of flavour violation, which are tightly constrained by precision experiments. This has posed a challenge to construct flavour models which both explain the structure of the Standard Model Yukawa couplings and also predict soft-breaking patterns that are compatible with these constraints. While such models have been studied in great detail, the impact of flavour violating soft terms on the Higgs mass at the two-loop level has been assumed to be small or negligible. In this letter, we show that large flavour violation in the up-squark sector can give a positive or negative mass shift to the SM-like Higgs of several GeV, without being in conflict with other observations. We investigate in which regions of the parameter space these effects can be expected.

  4. Study of Two-Loop Neutrino Mass Generation Models

    CERN Document Server

    Geng, Chao-Qiang

    2015-01-01

    We study the models with the Majorana neutrino masses generated radiatively by two-loop diagrams due to the Yukawa $\\rho \\bar \\ell_R^c \\ell_R$ and effective $\\rho^{\\pm\\pm} W^\\mp W^\\mp$ couplings along with a scalar triplet $\\Delta$, where $\\rho$ is a doubly charged singlet scalar, $\\ell_R$ the charged lepton and $W$ the charged gauge boson. A generic feature in these types of models is that the neutrino mass spectrum has to be a normal hierarchy. Furthermore, by using the neutrino oscillation data and comparing with the global fitting result in the literature, we find a unique neutrino mass matrix and predict the Dirac and two Majorana CP phases to be $1.40\\pi$, $1.11\\pi$ and $1.47\\pi$, respectively. We also discuss the model parameters constrained by the lepton flavor violating processes and electroweak oblique parameters. In addition, we show that the rate of the neutrinoless double beta decay $(0\

  5. Hard matching for boosted tops at two loops

    Energy Technology Data Exchange (ETDEWEB)

    Hoang, Andre H. [Vienna Univ. (Austria). Faculty of Physics; Vienna Univ. (Austria). Erwin Schroeder International Institute for Mathematical Physics; Pathak, Aditya; Stewart, Iain W. [Massachusetts Institute of Technology, Cambridge, MA (United States). Center for Theoretical Physics; Pietrulewicz, Piotr [DESY Hamburg (Germany). Theory Group

    2015-08-15

    Cross sections for top quarks provide very interesting physics opportunities, being both sensitive to new physics and also perturbatively tractable due to the large top quark mass. Rigorous factorization theorems for top cross sections can be derived in several kinematic scenarios, including the boosted regime in the peak region that we consider here. In the context of the corresponding factorization theorem for e{sup +}e{sup -} collisions we extract the last missing ingredient that is needed to evaluate the cross section differential in the jet-mass at two-loop order, namely the matching coefficient at the scale μ ≅ m{sub t}. Our extraction also yields the final ingredients needed to carry out logarithmic resummation at next-to-next-to-leading logarithmic order (or N3LL if we ignore the missing 4-loop cusp anomalous dimension). This coefficient exhibits an amplitude level rapidity logarithm starting at O(α{sup 2}{sub s}) due to virtual top quark loops, which we treat using rapidity renormalization group (RG) evolution. Interestingly, this rapidity RG evolution appears in the matching coefficient between two effective theories around the heavy quark mass scale μ≅m{sub t}.

  6. Coherent neutrino radiation in supernovae at two loops

    Science.gov (United States)

    Sedrakian, A.; Dieperink, A. E. L.

    2000-10-01

    We develop a neutrino transport theory, in terms of the real-time nonequilibrium Green's functions, which is applicable to physical conditions arbitrary far from thermal equilibrium. We compute the coherent neutrino radiation in cores of supernovae by evaluating the two-particle-two-hole (2p-2h) polarization function with dressed propagators. The propagator dressing is carried out in the particle-particle channel to all orders in the interaction. We show that at two loops there are two distinct sources of coherence effects in the bremsstrahlung. One is the generically off-shell intermediate state propagation, which leads to the Landau-Pomeranchuk-Migdal type suppression of radiation. We extend previous perturbative results, obtained in the leading order in quasiparticle width, by deriving the exact nonperturbative expression. A new contribution due to off-shell final or initial baryon states is treated in the leading order in the quasiparticle width. The latter contribution corresponds to processes of higher order than second order in the virial expansion in the number of quasiparticles. At the 2p-2h level, the time component of the polarization tensor for the vector transitions vanishes identically in the soft neutrino approximation. Vector current thereby is conserved. The contraction of the neutral axial vector current with the tensor interaction among the baryons leads to a nonvanishing contribution to the bremsstrahlung rate. These rates are evaluated numerically for finite temperature pure neutron matter at and above the nuclear saturation density.

  7. N >= 4 Supergravity Amplitudes from Gauge Theory at Two Loops

    Energy Technology Data Exchange (ETDEWEB)

    Boucher-Veronneau, C.; Dixon, L.J.; /SLAC

    2012-02-15

    We present the full two-loop four-graviton amplitudes in N = 4, 5, 6 supergravity. These results were obtained using the double-copy structure of gravity, which follows from the recently conjectured color-kinematics duality in gauge theory. The two-loop four-gluon scattering amplitudes in N = 0, 1, 2 supersymmetric gauge theory are a second essential ingredient. The gravity amplitudes have the expected infrared behavior: the two-loop divergences are given in terms of the squares of the corresponding one-loop amplitudes. The finite remainders are presented in a compact form. The finite remainder for N = 8 supergravity is also presented, in a form that utilizes a pure function with a very simple symbol.

  8. Two-Loop Renormalization in the Standard Model

    CERN Document Server

    Actis, S; Passarino, G; Passera, M

    2006-01-01

    In this paper the building blocks for the two-loop renormalization of the Standard Model are introduced with a comprehensive discussion of the special vertices induced in the Lagrangian by a particular diagonalization of the neutral sector and by two alternative treatments of the Higgs tadpoles. Dyson resummed propagators for the gauge bosons are derived, and two-loop Ward-Slavnov-Taylor identities are discussed. In part II, the complete set of counterterms needed for the two-loop renormalization will be derived. In part III, a renormalization scheme will be introduced, connecting the renormalized quantities to an input parameter set of (pseudo-)experimental data, critically discussing renormalization of a gauge theory with unstable particles.

  9. Two-loop RGE of a general renormalizable Yang-Mills theory in a renormalization scheme with an explicit UV cutoff

    CERN Document Server

    Chankowski, Piotr H; Meissner, Krzysztof A

    2016-01-01

    We perform a systematic one-loop renormalization of a general renormalizable Yang-Mills theory coupled to scalars and fermions using a regularization scheme with an explicit UV momentum cutoff $\\Lambda$. We construct the necessary finite counterterms restoring the BRST invariance of the effective action by analyzing the relevant Slavnov-Taylor identities. We find the relation between the renormalized parameters in our scheme and in the conventional $\\overline{\\rm MS}$ scheme which allow us to obtain the explicit two-loop renormalization group equations in our scheme from the known two-loop ones in the $\\overline{\\rm MS}$ scheme. We calculate in our scheme the divergences of two-loop vacuum graphs in the presence of a constant scalar background field which allow us to rederive the two-loop beta functions for parameters of the scalar potential. We also prove that consistent application of the proposed regularization leads to counterterms which, together with the original action, combine to a bare action express...

  10. Two-loop RGE of a general renormalizable Yang-Mills theory in a renormalization scheme with an explicit UV cutoff

    Energy Technology Data Exchange (ETDEWEB)

    Chankowski, Piotr H. [Institute of Theoretical Physics, Faculty of Physics, University of Warsaw,Pasteura 5, 02-093 Warsaw (Poland); Lewandowski, Adrian [Max-Planck-Institut für Gravitationsphysik (Albert-Einstein-Institut),Mühlenberg 1, D-14476 Potsdam (Germany); Institute of Theoretical Physics, Faculty of Physics, University of Warsaw,Pasteura 5, 02-093 Warsaw (Poland); Meissner, Krzysztof A. [Institute of Theoretical Physics, Faculty of Physics, University of Warsaw,Pasteura 5, 02-093 Warsaw (Poland)

    2016-11-18

    We perform a systematic one-loop renormalization of a general renormalizable Yang-Mills theory coupled to scalars and fermions using a regularization scheme with a smooth momentum cutoff Λ (implemented through an exponential damping factor). We construct the necessary finite counterterms restoring the BRST invariance of the effective action by analyzing the relevant Slavnov-Taylor identities. We find the relation between the renormalized parameters in our scheme and in the conventional (MS)-bar scheme which allow us to obtain the explicit two-loop renormalization group equations in our scheme from the known two-loop ones in the (MS)-bar scheme. We calculate in our scheme the divergences of two-loop vacuum graphs in the presence of a constant scalar background field which allow us to rederive the two-loop beta functions for parameters of the scalar potential. We also prove that consistent application of the proposed regularization leads to counterterms which, together with the original action, combine to a bare action expressed in terms of bare parameters. This, together with treating Λ as an intrinsic scale of a hypothetical underlying finite theory of all interactions, offers a possibility of an unconventional solution to the hierarchy problem if no intermediate scales between the electroweak scale and the Planck scale exist.

  11. Two-loop RGE of a general renormalizable Yang-Mills theory in a renormalization scheme with an explicit UV cutoff

    Science.gov (United States)

    Chankowski, Piotr H.; Lewandowski, Adrian; Meissner, Krzysztof A.

    2016-11-01

    We perform a systematic one-loop renormalization of a general renormalizable Yang-Mills theory coupled to scalars and fermions using a regularization scheme with a smooth momentum cutoff Λ (implemented through an exponential damping factor). We construct the necessary finite counterterms restoring the BRST invariance of the effective action by analyzing the relevant Slavnov-Taylor identities. We find the relation between the renormalized parameters in our scheme and in the conventional overline{MS} scheme which allow us to obtain the explicit two-loop renormalization group equations in our scheme from the known two-loop ones in the overline{MS} scheme. We calculate in our scheme the divergences of two-loop vacuum graphs in the presence of a constant scalar background field which allow us to rederive the two-loop beta functions for parameters of the scalar potential. We also prove that consistent application of the proposed regularization leads to counterterms which, together with the original action, combine to a bare action expressed in terms of bare parameters. This, together with treating Λ as an intrinsic scale of a hypothetical underlying finite theory of all interactions, offers a possibility of an unconventional solution to the hierarchy problem if no intermediate scales between the electroweak scale and the Planck scale exist.

  12. Exact Combinatorics of Bern-Kosower-type Amplitudes for Two-Loop $\\Phi^{3}$ Theory

    CERN Document Server

    Sato, H T; Sato, Haru-Tada; Schmidt, Michael G.

    1998-01-01

    Counting the contribution rate of a world-line formula to Feynman diagrams in Bern-Kosower-like amplitudes derived from a bosonic string theory for $N$-point two-loop Feynman amplitudes. In this connection we also present a method to derive simple and compact world-line forms for the effective action.

  13. Two-loop top-Yukawa-coupling corrections to the charged Higgs-boson mass in the MSSM

    Energy Technology Data Exchange (ETDEWEB)

    Hollik, Wolfgang [Max-Planck-Institut fuer Physik (Werner-Heisenberg-Institut), Muenchen (Germany); Passehr, Sebastian [Deutsches Elektronen-Synchrotron DESY, Hamburg (Germany)

    2015-07-15

    The top-Yukawa-coupling enhanced two-loop corrections to the charged Higgs-boson mass in the real MSSM are presented. The contributing two-loop self-energies are calculated in the Feynman-diagrammatic approach in the gaugeless limit with vanishing external momentum and bottom mass, within a renormalization scheme comprising on-shell and DR conditions. Numerical results illustrate the effect of the O(α{sub t}{sup 2}) contributions and the importance of the two-loop corrections to the mass of the charged Higgs bosons. (orig.)

  14. Two-Loop Maximal Unitarity with External Masses

    CERN Document Server

    Johansson, Henrik; Larsen, Kasper J

    2013-01-01

    We extend the maximal unitarity method at two loops to double-box basis integrals with up to three external massive legs. We use consistency equations based on the requirement that integrals of total derivatives vanish. We obtain unique formulae for the coefficients of the master double-box integrals. These formulae can be used either analytically or numerically.

  15. An Overview of Maximal Unitarity at Two Loops

    CERN Document Server

    Johansson, Henrik; Larsen, Kasper J.

    2012-01-01

    We discuss the extension of the maximal-unitarity method to two loops, focusing on the example of the planar double box. Maximal cuts are reinterpreted as contour integrals, with the choice of contour fixed by the requirement that integrals of total derivatives vanish on it. The resulting formulae, like their one-loop counterparts, can be applied either analytically or numerically.

  16. Two loop low temperature corrections to electron self energy

    Institute of Scientific and Technical Information of China (English)

    Mahnaz Q. Haseeb; Samina S. Masood

    2011-01-01

    We recalculate the two loop corrections in the background heat bath using real time formalism. The procedure of the integrations of loop momenta with dependence on finite temperature before the momenta without it has been followed. We determine the mass a

  17. Local integrands for two-loop QCD amplitudes

    CERN Document Server

    Badger, Simon; Peraro, Tiziano

    2016-01-01

    In this talk we review the recent computation of the five- and six-gluon two-loop amplitudes in Yang-Mills theory using local integrands which make the infrared pole structure manifest. We make some remarks on the connection with BCJ relations and the all-multiplicity structure.

  18. Two-Loop Tensor Integrals in Quantum Field Theory

    CERN Document Server

    Actis, S; Passarino, G; Passera, M; Uccirati, S

    2004-01-01

    A comprehensive study is performed of general massive, tensor, two-loop Feynman diagrams with two and three external legs. Reduction to generalized scalar functions is discussed and integral representations are introduced, family-by-family of diagrams, that support the same class of algorithms (algorithms of smoothness) already employed for the numerical evaluation of ordinary scalar functions.

  19. Two-loop beta functions for supersymmetric gauge theories

    Energy Technology Data Exchange (ETDEWEB)

    Jack, I. (Imperial Coll. of Science and Technology, London (UK). Blackett Lab.)

    1984-11-15

    The two-loop ..beta.. functions in the dimensional regularisation framework for a general gauge theory coupled to scalar and spinor fields are presented and by means of a finite transformation of the couplings are converted into a form which vanishes for special cases corresponding to supersymmetric gauge theories.

  20. Two-loop and n-loop eikonal vertex corrections

    OpenAIRE

    Kidonakis, Nikolaos

    2003-01-01

    I present calculations of two-loop vertex corrections with massive and massless partons in the eikonal approximation. I show that the $n$-loop result for the UV poles can be given in terms of the one-loop calculation.

  1. Constraints on abelian extensions of the Standard Model from two-loop vacuum stability and U(1) B- L

    Science.gov (United States)

    Corianò, Claudio; Rose, Luigi Delle; Marzo, Carlo

    2016-02-01

    We present a renormalization group study of the scalar potential in a minimal U(1) B- L extension of the Standard Model involving one extra heavier Higgs and three heavy right-handed neutrinos with family universal B-L charge assignments. We implement a type-I seesaw for the masses of the light neutrinos of the Standard Model. In particular, compared to a previous study, we perform a two-loop extension of the evolution, showing that two-loop effects are essential for the study of the stability of the scalar potential up to the Planck scale. The analysis includes the contribution of the kinetic mixing between the two abelian gauge groups, which is radiatively generated by the evolution, and the one-loop matching conditions at the electroweak scale. By requiring the stability of the potential up to the Planck mass, significant constraints on the masses of the heavy neutrinos, on the gauge couplings and the mixing in the Higgs sector are identified.

  2. Constraints on Abelian Extensions of the Standard Model from Two-Loop Vacuum Stability and $U(1)_{B-L}$

    CERN Document Server

    Coriano, Claudio; Marzo, Carlo

    2015-01-01

    We present a renormalization group study of the scalar potential in a minimal $U(1)_{B-L}$ extension of the Standard Model involving one extra heavier Higgs and three heavy right-handed neutrinos with family universal B-L charge assignments. We implement a type-I seesaw for the masses of the light neutrinos of the Standard Model. In particular, compared to a previous study, we perform a two-loop extension of the evolution, showing that two-loop effects are essential for the study of the stability of the scalar potential up to the Planck scale. The analysis includes the contribution of the kinetic mixing between the two abelian gauge groups, which is radiatively generated by the evolution, and the one-loop matching conditions at the electroweak scale. By requiring the stability of the potential up to the Planck mass, significant constraints on the masses of the heavy neutrinos, on the gauge couplings and the mixing in the Higgs sector are identified.

  3. Towards a Basis for Planar Two-Loop Integrals

    CERN Document Server

    Gluza, Janusz; Kosower, David A

    2010-01-01

    The existence of a finite basis of algebraically independent one-loop integrals has underpinned important developments in the computation of one-loop amplitudes in field theories and gauge theories in particular. We give an explicit construction reducing integrals to a finite basis for planar integrals at two loops, both to all orders in the dimensional regulator e, and also when all integrals are truncated to O(e). We show how to reorganize integration-by-parts equations to obtain elements of the first basis efficiently, and how to use Gram determinants to obtain additional linear relations reducing this all-orders basis to the second one. The techniques we present should apply to non-planar integrals, to integrals with massive propagators, and beyond two loops as well.

  4. Two-loop corrections to Higgs boson production

    Energy Technology Data Exchange (ETDEWEB)

    Ravindran, V. [Harish-Chandra Research Institute, Chhatnag Road, Jhusi, Allahabad 211019 (India); Smith, J. [C.N. Yang Institute for Theoretical Physics, State University of New York, Stony Brook, NY 11794-3840 (United States); Neerven, W.L. van [Instituut-Lorentz, University of Leiden, PO Box 9506, 2300 RA Leiden (Netherlands)]. E-mail: neerven@lorentz.leidenuniv.nl

    2005-01-03

    In this paper we present the complete two-loop vertex corrections to scalar and pseudo-scalar Higgs boson production for general colour factors for the gauge group SU(N) in the limit where the top quark mass gets infinite. We derive a general formula for the vertex correction which holds for conserved and non-conserved operators. For the conserved operator we take the electromagnetic vertex correction as an example whereas for the non-conserved operators we take the two vertex corrections above. Our observations for the structure of the pole terms 1/-bar 4, 1/-bar 3 and 1/-bar 2 in two loop order are the same as made earlier in the literature for electromagnetism. However, we also elucidate the origin of the second order single pole term which is equal to the second order singular part of the anomalous dimension plus a universal function which is the same for the quark and the gluon.

  5. Two-Loop SL(2) Form Factors and Maximal Transcendentality

    CERN Document Server

    Loebbert, Florian; Wilhelm, Matthias; Yang, Gang

    2016-01-01

    Form factors of composite operators in the SL(2) sector of N=4 SYM theory are studied up to two loops via the on-shell unitarity method. The non-compactness of this subsector implies the novel feature and technical challenge of an unlimited number of loop momenta in the integrand's numerator. At one loop, we derive the full minimal form factor to all orders in the dimensional regularisation parameter. At two loops, we construct the complete integrand for composite operators with an arbitrary number of covariant derivatives, and we obtain the remainder functions as well as the dilatation operator for composite operators with up to three covariant derivatives. The remainder functions reveal curious patterns suggesting a hidden maximal uniform transcendentality for the full form factor. Finally, we speculate about an extension of these patterns to QCD.

  6. Two-Loop Renormalization in the Standard Model

    CERN Document Server

    Actis, S

    2006-01-01

    In part I and II of this series of papers all elements have been introduced to extend, to two loops, the set of renormalization procedures which are needed in describing the properties of a spontaneously broken gauge theory. In this paper, the final step is undertaken and finite renormalization is discussed. Two-loop renormalization equations are introduced and their solutions discussed within the context of the minimal standard model of fundamental interactions. These equations relate renormalized Lagrangian parameters (couplings and masses) to some input parameter set containing physical (pseudo-)observables. Complex poles for unstable gauge and Higgs bosons are used and a consistent setup is constructed for extending the predictivity of the theory from the Lep1 Z-boson scale (or the Lep2 WW scale) to regions of interest for LHC and ILC physics.

  7. A two-loop excitation control system for synchronous generators

    Energy Technology Data Exchange (ETDEWEB)

    Alvarez-Ramirez, Jose; Cervantes, Ilse; Escarela-Perez, Rafael; Espinosa-Perez, Gerardo [Seccion de Estudios de Posgrado e Investigacion ESIME-C, Av. Santa Ana 1000 Col. San Francisco Culhuacan, Mexico D.F. 04430 (Mexico)

    2005-10-01

    An excitation controller for a single generator based on modern multi-loop design methodology is presented in this paper. The proposed controller consists of two-loops: a stabilizing (damping injection) loop and a voltage regulating loop. The task of the stabilizing loop is to add damping in the face of voltage oscillations. The voltage regulating loop is basically a PI compensator whose objective is to obtain terminal voltage regulation about the prescribed reference. The main contribution of this paper is to give some insights into the systematic derivation of multi-loop controllers of power generators. Certain connections between the two-loop excitation controller and standard PSS-AVR schemes are discussed. In this way, some insight into the stability of the standard PSS scheme is obtained from the analysis of the proposed controller. The proposed controller is evaluated via numerical simulations on a full finite-element model. (author)

  8. Analytic two-loop form factors in N=4 SYM

    CERN Document Server

    Brandhuber, Andreas; Yang, Gang

    2012-01-01

    We derive a compact expression for the three-point MHV form factors of half-BPS operators in N=4super Yang-Mills at two loops. The main tools of our calculation are generalised unitarity applied at the form factor level, and the compact expressions for supersymmetric tree-level form factors and amplitudes entering the cuts. We confirm that infrared divergences exponentiate as expected, and that collinear factorisation is entirely captured by an ABDK/BDS ansatz. Next, we construct the two-loop remainder function obtained by subtracting this ansatz from the full two-loop form factor and compute it numerically. Using symbology, combined with various physical constraints and symmetries, we find a unique solution for its symbol. With this input we construct a remarkably compact analytic expression for the remainder function, which contains only classical polylogarithms, and compare it to our numerical results. Furthermore, we make the surprising observation that our remainder is equal to the maximally transcendent...

  9. Avoiding the Goldstone Boson Catastrophe in general renormalisable field theories at two loops

    CERN Document Server

    Braathen, Johannes

    2016-01-01

    We show how the infra-red divergences associated to Goldstone bosons in the minimum condition of the two-loop Landau-gauge effective potential can be avoided in general field theories. This extends the resummation formalism recently developed for the Standard Model and the MSSM, and we give compact, infra-red finite expressions in closed form for the tadpole equations. We also show that the results at this loop order are equivalent to (and are most easily obtained by) imposing an "on-shell" condition for the Goldstone bosons. Moreover, we extend the approach to show how the infra-red divergences in the calculation of the masses of neutral scalars (such as the Higgs boson) can be eliminated. For the mass computation, we specialise to the gaugeless limit and extend the effective potential computation to allow the masses to be determined without needing to solve differential equations for the loop functions -- opening the door to fast, infra-red safe determinations of the Higgs mass in general theories.

  10. Avoiding the Goldstone Boson Catastrophe in general renormalisable field theories at two loops

    Energy Technology Data Exchange (ETDEWEB)

    Braathen, Johannes; Goodsell, Mark D. [LPTHE, UPMC University Paris 06, Sorbonne Universités,4 Place Jussieu, F-75252 Paris (France); LPTHE, CNRS,4 Place Jussieu, F-75252 Paris (France)

    2016-12-14

    We show how the infra-red divergences associated to Goldstone bosons in the minimum condition of the two-loop Landau-gauge effective potential can be avoided in general field theories. This extends the resummation formalism recently developed for the Standard Model and the MSSM, and we give compact, infra-red finite expressions in closed form for the tadpole equations. We also show that the results at this loop order are equivalent to (and are most easily obtained by) imposing an “on-shell” condition for the Goldstone bosons. Moreover, we extend the approach to show how the infra-red divergences in the calculation of the masses of neutral scalars (such as the Higgs boson) can be eliminated. For the mass computation, we specialise to the gaugeless limit and extend the effective potential computation to allow the masses to be determined without needing to solve differential equations for the loop functions — opening the door to fast, infra-red safe determinations of the Higgs mass in general theories.

  11. Hard photon production from unsaturated quark-gluon plasma at two-loop level

    Energy Technology Data Exchange (ETDEWEB)

    Dutta, D. E-mail: ddutta@apsara.barc.ernet.in; Sastry, S.V.S.; Mohanty, A.K.; Kumar, K

    2002-11-18

    The hard photon production from bremsstrahlung and annihilation with scattering that arise at two-loop level are estimated for a chemically non-equilibrated quark-gluon plasma in the framework of Hard Thermal Loop (HTL) resummed effective field theory. The rate of photon production is found to be suppressed due to unsaturated phase space compared to equilibrated plasma. For an unsaturated plasma, unlike the effective one-loop case, the reduction in the effective two-loop processes is found to be independent of gluon fugacity, due to an additional collinear enhancement arising from the decrease in thermal quark mass but strongly depends on quark and antiquark fugacities. It is also found that the photon production is dominated by bremsstrahlung mechanism, since the phase space suppression is higher for annihilation with scattering, in contrast to the equilibrated plasma where annihilation with scattering dominates the photon production.

  12. The muon magnetic moment in the 2HDM: complete two-loop result

    Science.gov (United States)

    Cherchiglia, Adriano; Kneschke, Patrick; Stöckinger, Dominik; Stöckinger-Kim, Hyejung

    2017-01-01

    We study the 2HDM contribution to the muon anomalous magnetic moment a μ and present the complete two-loop result, particularly for the bosonic contribution. We focus on the Aligned 2HDM, which has general Yukawa couplings and contains the type I, II, X, Y models as special cases. The result is expressed with physical parameters: three Higgs boson masses, Yukawa couplings, two mixing angles, and one quartic potential parameter. We show that the result can be split into several parts, each of which has a simple parameter dependence, and we document their general behavior. Taking into account constraints on parameters, we find that the full 2HDM contribution to a μ can accommodate the current experimental value, and the complete two-loop bosonic contribution can amount to (2⋯4) × 10-10, more than the future experimental uncertainty.

  13. On the impact of kinetic mixing in beta functions at two-loop

    CERN Document Server

    Lyonnet, Florian

    2016-01-01

    Kinetic mixing is a fundamental property of models with a gauge symmetry involving several $\\mathrm{U}(1)$ group factors. In this paper, we perform a numerical study of the impact of kinetic mixing on beta functions at two-loop. To do so, we use the recently published PyR@TE 2 software to derive the complete set of RGEs of the SM B-L model at two-loop including kinetic mixing. We show that it is important to properly account for kinetic mixing as the evolution of the parameters with the energy scale can change drastically. In some cases, these modifications can even lead to a different conclusion regarding the stability of the scalar potential.

  14. The muon magnetic moment in the ${\\rm{2HDM}}$: complete two-loop result

    CERN Document Server

    Cherchiglia, Adriano; Stöckinger, Dominik; Stöckinger-Kim, Hyejung

    2016-01-01

    We study the ${\\rm{2HDM}}$ contribution to the muon anomalous magnetic moment $a_\\mu$ and present the complete two-loop result, particularly for the bosonic contribution. We focus on the Aligned ${\\rm{2HDM}}$, which has general Yukawa coupling constants and is more general than the type I, II, X, Y models. The result is expressed with physical parameters: three Higgs boson masses, Yukawa couplings, two mixing angles, and one quartic potential parameter. We show that the result can be split into several parts, each of which has a simple parameter dependence, and we document the general behavior. Taking into account constraints on parameters, we find that the full ${\\rm{2HDM}}$ contribution to $a_\\mu$ can accommodate the current experimental value, and the complete two-loop bosonic result contribution can amount to $(2\\cdots 4)\\times 10^{-10}$, more than the future experimental uncertainty.

  15. Higgs boson couplings to bottom quarks: two-loop supersymmetry-QCD corrections.

    Science.gov (United States)

    Noth, David; Spira, Michael

    2008-10-31

    We present two-loop supersymmetry (SUSY) QCD corrections to the effective bottom Yukawa couplings within the minimal supersymmetric extension of the standard model (MSSM). The effective Yukawa couplings include the resummation of the nondecoupling corrections Deltam_{b} for large values of tanbeta. We have derived the two-loop SUSY-QCD corrections to the leading SUSY-QCD and top-quark-induced SUSY-electroweak contributions to Deltam_{b}. The scale dependence of the resummed Yukawa couplings is reduced from O(10%) to the percent level. These results reduce the theoretical uncertainties of the MSSM Higgs branching ratios to the accuracy which can be achieved at a future linear e;{+}e;{-} collider.

  16. Two-loop gg → Hg amplitude mediated by a nearly massless quark

    Science.gov (United States)

    Melnikov, Kirill; Tancredi, Lorenzo; Wever, Christopher

    2016-11-01

    We analytically compute the two-loop scattering amplitude gg → Hg assuming that the mass of the quark, that mediates the ggH interaction, is vanishingly small. Our computation provides an important ingredient required to improve the theoretical description of the top-bottom interference effect in Higgs boson production in gluon fusion, and to elucidate its impact on the Higgs boson transverse momentum distribution.

  17. Two-loop $gg \\to Hg$ amplitude mediated by a nearly massless quark

    CERN Document Server

    Melnikov, Kirill; Wever, Christopher

    2016-01-01

    We analytically compute the two-loop scattering amplitude $gg \\to Hg$ assuming that the mass of the quark, that mediates the ggH interaction, is vanishingly small. Our computation provides an important ingredient required to improve the theoretical description of the top-bottom interference effect in Higgs boson production in gluon fusion, and to elucidate its impact on the Higgs boson transverse momentum distribution.

  18. Screening and damping effects on the thermodynamic potential in QGP

    Institute of Scientific and Technical Information of China (English)

    王欣; 李家荣

    2003-01-01

    By using the spectral functions of gluons, which contain Debye screening and soft damping effects,the effective two-loop thermodynamic potential in quark-gluon plasma was evaluated via real-time temperatureQCD. The result that depends on screening and damping of gluons as physical parameters is obtained. It canbe seen that our analytical result and the recent lattice results are in agreement for T〉~2Tc.

  19. A two-loop study of the deconfinement transition in Yang-Mills theories: SU(3) and beyond

    CERN Document Server

    Reinosa, U; Tissier, M; Wschebor, N

    2015-01-01

    We study the confinement-deconfinement phase transition of pure Yang-Mills theories at finite temperature within a simple massive extension of standard background field methods. We generalize our recent next-to-leading-order perturbative calculation of the Polyakov loop and the related background field effective potential for the SU(2) theory to any compact and connex Lie group with a simple Lie algebra. We discuss in detail the SU(3) theory, where the two-loop corrections yield improved values for the first order transition temperature as compared to the one-loop result. We show that certain one-loop artifacts of thermodynamical observables disappear at two-loop order, as was already the case for the SU(2) theory. In particular, the entropy and the pressure are positive for all temperatures. We also discuss the groups SU(4) and Sp(2) which shed interesting light, respectively, on the relation between the (de)confinement of static matter sources in the various representations of the gauge group and on the use...

  20. Optimized Perturbation Theory at Finite Temperature Two-Loop Analysis

    CERN Document Server

    Chiku, S

    2000-01-01

    We study the optimized perturbation theory (OPT) at finite temperature, which is a self-consistent resummation method. Firstly, we generalize the idea of the OPT to optimize the coupling constant in lambda phi^4 theory, and give a proof of the renormalizability of this generalized OPT. Secondly, the principle of minimal sensitivity and the criterion of the fastest apparent convergence, which are conditions to determine the optimal parameter values, are examined in lambda phi^4 theory. Both conditions exhibit a second-order transition at finite temperature with critical exponent beta = 0.5 in the two-loop approximation.

  1. Numerical Computation of Two-loop Box Diagrams with Masses

    CERN Document Server

    Yuasa, F; Hamaguchi, N; Ishikawa, T; Kato, K; Kurihara, Y; Fujimoto, J; Shimizu, Y

    2011-01-01

    A new approach is presented to evaluate multi-loop integrals, which appear in the calculation of cross-sections in high-energy physics. It relies on a fully numerical method and is applicable to a wide class of integrals with various mass configurations. As an example, the computation of two-loop planar and non-planar box diagrams is shown. The results are confirmed by comparisons with other techniques, including the reduction method, and by a consistency check using the dispersion relation.

  2. Two-loop Dirac neutrino mass and WIMP dark matter

    CERN Document Server

    Bonilla, Cesar; Peinado, Eduardo; Valle, Jose W F

    2016-01-01

    We propose a "scotogenic" mechanism relating small neutrino mass and cosmological dark matter. Neutrinos are Dirac fermions with masses arising only in two--loop order through the sector responsible for dark matter. Two triality symmetries ensure both dark matter stability and strict lepton number conservation at higher orders. A global spontaneously broken U(1) symmetry leads to a physical $Diracon$ that induces invisible Higgs decays which add up to the Higgs to dark matter mode. This enhances sensitivities to spin-independent WIMP dark matter search below $m_h/2$.

  3. Two loop low temperature corrections to electron self energy

    Institute of Scientific and Technical Information of China (English)

    Mahnaz Q. Haseeb; Samina S. Masood

    2011-01-01

    We xecalculate the two loop corrections in the background heat bath using real time formalism.The procedure of the integrations of loop momenta with dependence on finite temperature before the moments without it has been followed. We determine the mass and wavefunction renormalization constants in the low temperature limit of QED, for the first time with this preferred order of integrations. The correction to electron mass and spinors in this limit is important in the early universe at the time of primordial nucleosynthesis as well as in astrophysics.

  4. Two-loop electroweak threshold corrections in the Standard Model

    Directory of Open Access Journals (Sweden)

    Bernd A. Kniehl

    2015-07-01

    Full Text Available We study the relationships between the basic parameters of the on-shell renormalization scheme and their counterparts in the MS¯ scheme at full order O(α2 in the Standard Model. These enter as threshold corrections the renormalization group analyses underlying, e.g., the investigation of the vacuum stability. To ensure the gauge invariance of the parameters, in particular of the MS¯ masses, we work in Rξ gauge and systematically include tadpole contributions. We also consider the gaugeless-limit approximation and compare it with the full two-loop electroweak calculation.

  5. Coherent neutrino radiation in supernovae at two loops

    OpenAIRE

    Sedrakian, A.; Dieperink, A. E. L.

    2000-01-01

    We develop a neutrino transport theory, in terms of the real-time non-equilibrium Green's functions, which is applicable to physical conditions arbitrary far from thermal equilibrium. We compute the coherent neutrino radiation in cores of supernovae by evaluating the two-particle-two-hole (2p-2h) polarization function with dressed propagators. The propagator dressing is carried out in the particle-particle channel to all orders in the interaction. We show that at two loops there are two disti...

  6. Two-Loop Fermionic Corrections to Massive Bhabha Scattering

    CERN Document Server

    Actis, S; Gluza, J; Riemann, T

    2007-01-01

    We evaluate the two-loop corrections to Bhabha scattering from fermion loops in the context of pure Quantum Electrodynamics. The differential cross section is expressed by a small number of Master Integrals with exact dependence on the fermion masses me, mf and the Mandelstam invariants s,t,u. We determine the limit of fixed scattering angle and high energy, assuming the hierarchy of scales me^2 << mf^2 << s,t,u. The numerical result is combined with the available non-fermionic contributions. As a by-product, we provide an independent check of the known electron-loop contributions.

  7. Eikonal gluon bremsstrahlung at finite Nc beyond two loops

    Science.gov (United States)

    Delenda, Yazid; Khelifa-Kerfa, Kamel

    2016-03-01

    We present a general formalism for computing the matrix-element squared for the emission of soft energy-ordered gluons beyond two loops in QCD perturbation theory at finite Nc. Our formalism is valid in the eikonal approximation. A Mathematica program has been developed for the automated calculation of all real/virtual eikonal squared amplitudes needed at a given loop order. For the purpose of illustration, we show the explicit forms of the eikonal squared amplitudes up to the fifth-loop order. In the large-Nc limit, our results coincide with those previously reported in literature.

  8. Turbulent magnetic Prandtl number in helical kinematic magnetohydrodynamic turbulence: two-loop renormalization group result.

    Science.gov (United States)

    Jurčišinová, E; Jurčišin, M; Remecký, R; Zalom, P

    2013-04-01

    Using the field theoretic renormalization group technique, the influence of helicity (spatial parity violation) on the turbulent magnetic Prandtl number in the kinematic magnetohydrodynamic turbulence is investigated in the two-loop approximation. It is shown that the presence of helicity decreases the value of the turbulent magnetic Prandtl number and, at the same time, the two-loop helical contribution to the turbulent magnetic Prandtl number is at most 4.2% (in the case with the maximal helicity) of its nonhelical value. These results demonstrate, on one hand, the potential importance of the presence of asymmetries in processes in turbulent environments and, on the other hand, the rather strong stability of the properties of diffusion processes of the magnetic field in the conductive turbulent environment with the spatial parity violation in comparison to the corresponding systems without the spatial parity violation. In addition, obtained results are compared to the corresponding results found for the two-loop turbulent Prandtl number in the model of passively advected scalar field. It is shown that the turbulent Prandtl number and the turbulent magnetic Prandtl number, which are the same in fully symmetric isotropic turbulent systems, are essentially different when one considers the spatial parity violation. It means that the properties of the diffusion processes in the turbulent systems with a given symmetry breaking can considerably depend on the internal tensor structure of advected quantities.

  9. Two loop electroweak corrections from heavy fermions to b→s+γ

    Institute of Scientific and Technical Information of China (English)

    YANG Xiu-Yi; FENG Tai-Fu

    2010-01-01

    Applying an effective Lagrangian method and an on-shell scheme, we analyze the electroweak corrections to the rare decay b→, s+γ from some special two loop diagrams in which a closed heavy fermion loop is attached to the virtual charged gauge bosons or Higgs. At the decoupling limit where the virtual fermions in the inner loop are much heavier than the electroweak scale, we verify the final results satisfying the decoupling theorem explicitly when the interactions among Higgs and heavy fermions do not contain the nondecoupling couplings. Adopting the universal assumptions on the relevant couplings and mass spectrum of new physics, we find that the relative corrections from those two loop diagrams to the SM theoretical prediction on the branching ratio of B → Xsγ can reach 5% as the energy scale of new physics ANp=200 GeV.

  10. Two-Loop Scattering Amplitudes from the Riemann Sphere

    CERN Document Server

    Geyer, Yvonne; Monteiro, Ricardo; Tourkine, Piotr

    2016-01-01

    The scattering equations give striking formulae for massless scattering amplitudes at tree level and, as shown recently, at one loop. The progress at loop level was based on ambitwistor string theory, which naturally yields the scattering equations. We proposed that, for ambitwistor strings, the standard loop expansion in terms of the genus of the worldsheet is equivalent to an expansion in terms of nodes of a Riemann sphere, with the nodes carrying the loop momenta. In this paper, we show how to obtain two-loop scattering equations with the correct factorization properties. We adapt genus-two integrands from the ambitwistor string to the nodal Riemann sphere and show that these yield correct answers, by matching standard results for the four-point two-loop amplitudes of maximal supergravity and super-Yang-Mills theory. In the Yang-Mills case, this requires the loop analogue of the Parke-Taylor factor carrying the colour dependence, which includes non-planar contributions.

  11. Two-loop scattering amplitudes from the Riemann sphere

    Science.gov (United States)

    Geyer, Yvonne; Mason, Lionel; Monteiro, Ricardo; Tourkine, Piotr

    2016-12-01

    The scattering equations give striking formulas for massless scattering amplitudes at tree level and, as shown recently, at one loop. The progress at loop level was based on ambitwistor-string theory, which naturally yields the scattering equations. We proposed that, for ambitwistor strings, the standard loop expansion in terms of the genus of the world sheet is equivalent to an expansion in terms of nodes of a Riemann sphere, with the nodes carrying the loop momenta. In this paper, we show how to obtain two-loop scattering equations with the correct factorization properties. We adapt genus-two integrands from the ambitwistor string to the nodal Riemann sphere and show that these yield correct answers, by matching standard results for the four-point two-loop amplitudes of maximal supergravity and super-Yang-Mills theory. In the Yang-Mills case, this requires the loop analogue of the Parke-Taylor factor carrying the color dependence, which includes nonplanar contributions.

  12. Two-Loop Renormalization in the Standard Model

    CERN Document Server

    Actis, S

    2006-01-01

    In part I general aspects of the renormalization of a spontaneously broken gauge theory have been introduced. Here, in part II, two-loop renormalization is introduced and discussed within the context of the minimal Standard Model. Therefore, this paper deals with the transition between bare parameters and fields to renormalized ones. The full list of one- and two-loop counterterms is shown and it is proven that, by a suitable extension of the formalism already introduced at the one-loop level, two-point functions suffice in renormalizing the model. The problem of overlapping ultraviolet divergencies is analyzed and it is shown that all counterterms are local and of polynomial nature. The original program of 't Hooft and Veltman is at work. Finite parts are written in a way that allows for a fast and reliable numerical integration with all collinear logarithms extracted analytically. Finite renormalization, the transition between renormalized parameters and physical (pseudo-)observables, will be discussed in p...

  13. The two-loop electroweak bosonic corrections to sin2 ⁡ θeffb

    Science.gov (United States)

    Dubovyk, Ievgen; Freitas, Ayres; Gluza, Janusz; Riemann, Tord; Usovitsch, Johann

    2016-11-01

    The prediction of the effective electroweak mixing angle sin2 ⁡θeffb in the Standard Model at two-loop accuracy has now been completed by the first calculation of the bosonic two-loop corrections to the Z b bar b vertex. Numerical predictions are presented in the form of a fitting formula as function of MZ ,MW ,MH ,mt and Δα, αs. For central input values, we obtain a relative correction of Δκb (α2 , bos) = - 0.9855 ×10-4, amounting to about a quarter of the fermionic corrections, and corresponding to sin2 ⁡ θeffb = 0.232704. The integration of the corresponding two-loop vertex Feynman integrals with up to three dimensionless parameters in Minkowskian kinematics has been performed with two approaches: (i) Sector decomposition, implemented in the packages FIESTA 3 and SecDec 3, and (ii) Mellin-Barnes representations, implemented in AMBRE 3/MB and the new package MBnumerics.

  14. Gravitational Two-Loop Counterterm Is Asymptotically Safe

    Science.gov (United States)

    Gies, Holger; Knorr, Benjamin; Lippoldt, Stefan; Saueressig, Frank

    2016-05-01

    Weinberg's asymptotic safety scenario provides an elegant mechanism to construct a quantum theory of gravity within the framework of quantum field theory based on a non-Gaussian fixed point of the renormalization group flow. In this work we report novel evidence for the validity of this scenario, using functional renormalization group techniques to determine the renormalization group flow of the Einstein-Hilbert action supplemented by the two-loop counterterm found by Goroff and Sagnotti. The resulting system of beta functions comprises three scale-dependent coupling constants and exhibits a non-Gaussian fixed point which constitutes the natural extension of the one found at the level of the Einstein-Hilbert action. The fixed point exhibits two ultraviolet attractive and one repulsive direction supporting a low-dimensional UV-critical hypersurface. Our result vanquishes the long-standing criticism that asymptotic safety will not survive once a "proper perturbative counterterm" is included in the projection space.

  15. The Gravitational Two-Loop Counterterm is Asymptotically Safe

    CERN Document Server

    Gies, Holger; Lippoldt, Stefan; Saueressig, Frank

    2016-01-01

    Weinberg's asymptotic safety scenario provides an elegant mechanism to construct a quantum theory of gravity within the framework of quantum field theory based on a non-Gau{\\ss}ian fixed point of the renormalization group flow. In this work we report novel evidence for the validity of this scenario, using functional renormalization group techniques to determine the renormalization group flow of the Einstein-Hilbert action supplemented by the two-loop counterterm found by Goroff and Sagnotti. The resulting system of beta functions comprises three scale-dependent coupling constants and exhibits a non-Gau{\\ss}ian fixed point which constitutes the natural extension of the one found at the level of the Einstein-Hilbert action. The fixed point exhibits two ultraviolet attractive and one repulsive direction supporting a low-dimensional UV-critical hypersurface. Our result vanquishes the longstanding criticism that asymptotic safety will not survive once a "proper perturbative counterterm" is included in the projecti...

  16. Overcoming Obstacles to Colour-Kinematics Duality at Two Loops

    CERN Document Server

    Mogull, Gustav

    2015-01-01

    The discovery of colour-kinematics duality has allowed great progress in our understanding of the UV structure of gravity. However, it has proven difficult to find numerators which satisfy colour-kinematics duality in certain cases. We discuss obstacles to building a set of such numerators in the context of the five-gluon amplitude with all helicities positive at two loops. We are able to overcome the obstacles by adding more loop momentum to our numerator to accommodate tension between the values of certain cuts and the symmetries of certain diagrams. At the same time, we maintain control over the size of our ansatz by identifying a highly constraining but desirable symmetry property of our master numerator. The resulting numerators have twelve powers of loop momenta rather than the seven one would expect from the Feynman rules.

  17. Rapidity renormalized TMD soft and beam functions at two loops

    Energy Technology Data Exchange (ETDEWEB)

    Luebbert, Thomas [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik; Oredsson, Joel [DESY, Hamburg (Germany). Theory Group; Lund Univ. (Sweden). Dept. of Astronomy and Theoretical Physics; Stahlhofen, Maximilian [DESY, Hamburg (Germany). Theory Group; Mainz Univ. (Germany). PRISMA Cluster of Excellence

    2016-03-15

    We compute the transverse momentum dependent (TMD) soft function for the production of a color-neutral final state at the LHC within the rapidity renormalization group (RRG) framework to next-to-next-to-leading order (NNLO). We use this result to extract the universal renormalized TMD beam functions (aka TMDPDFs) in the same scheme and at the same order from known results in another scheme. We derive recurrence relations for the logarithmic structure of the soft and beam functions, which we use to cross check our calculation. We also explicitly confirm the non-Abelian exponentiation of the TMD soft function in the RRG framework at two loops. Our results provide the ingredients for resummed predictions of p {sub perpendicular} {sub to} -differential cross sections at NNLL' in the RRG formalism. The RRG provides a systematic framework to resum large (rapidity) logarithms through (R)RG evolution and assess the associated perturbative uncertainties.

  18. Two-loop-induced neutrino masses: A model-independent perspective

    CERN Document Server

    Sierra, D Aristizabal

    2015-01-01

    We discuss Majorana neutrino mass generation mechanisms at the two-loop order. After briefly reviewing the systematic classification of one-loop realizations, we then focus on a general two-loop classification scheme which provides a model-independent catalog for neutrino mass models at the two-loop order

  19. Leading Chiral Logarithms of $K_{S} \\to \\gamma \\gamma$ at two Loops

    CERN Document Server

    Ghorbani, Karim

    2014-01-01

    We obtain the leading divergences at two loops for the decay $K_{S} \\to \\gamma \\gamma$ using only one-loop diagrams. We then find the double chiral logarithmic corrections to the decay branching ratio. It turns out that these effects are numerically small and therefore make a very small enhancement on the branching ratio. We also derive an expression for the corrections of type $\\log \\mu~\\times$ LEC. We find out that these single logarithmic effects can be sizable but comes with opposite sign with respect to the double chiral logarithms. Some numerical results are presented.

  20. Perturbative Yukawa theory at finite density: the role of masses and renormalization group flow at two loops

    CERN Document Server

    Palhares, Letícia F

    2008-01-01

    Yukawa theory at vanishing temperature provides (one of the ingredients for) an effective description of the thermodynamics of a variety of cold and dense fermionic systems. We study the role of masses and the renormalization group flow in the calculation of the equation of state up to two loops within the MSbar scheme. Two-loop integrals are computed analytically for arbitrary fermion and scalar masses, and expressed in terms of well-known special functions. The dependence of the renormalization group flow on the number of fermion flavors is also discussed.

  1. World-line approach to the Bern-Kosower formalism in two-loop Yang-Mills theory

    CERN Document Server

    Sato, H T; Sato, Haru-Tada; Schmidt, Michael G.

    1999-01-01

    Based on the world-line formalism with a sewing method, we derive the Yang-Mills effective action in a form useful to generate the Bern-Kosower-type master formulae for gluon scattering amplitudes at the two-loop level. It is shown that four-gluon ($\\Phi^4$ type sewing) contributions can be encapsulated in the action with three-gluon ($\\Phi^3$ type) vertices only, the total action thus becoming a simple expression. We then derive a general formula for a two-loop Euler-Heisenberg type action in a pseudo-abelian $su(2)$ background. The ghost loop and fermion loop cases are also studied.

  2. The two-loop sunrise integral and elliptic polylogarithms

    Energy Technology Data Exchange (ETDEWEB)

    Adams, Luise; Weinzierl, Stefan [Institut fuer Physik, Johannes Gutenberg-Universitaet Mainz (Germany); Bogner, Christian [Institut fuer Physik, Humboldt-Universitaet zu Berlin (Germany)

    2016-07-01

    In this talk, we present a solution for the two-loop sunrise integral with arbitrary masses around two and four space-time dimensions in terms of a generalised elliptic version of the multiple polylogarithms. Furthermore we investigate the elliptic polylogarithms appearing in higher orders in the dimensional regularisation ε of the two-dimensional equal mass solution. Around two space-time dimensions the solution consists of a sum of three elliptic dilogarithms where the arguments have a nice geometric interpretation as intersection points of the integration region and an elliptic curve associated to the sunrise integral. Around four space-time dimensions the sunrise integral can be expressed with the ε{sup 0}- and ε{sup 1}-solution around two dimensions, mass derivatives thereof and simpler terms. Considering higher orders of the two-dimensional equal mass solution we find certain generalisations of the elliptic polylogarithms appearing in the ε{sup 0}- and ε{sup 1}-solutions around two and four space-time dimensions. We show that these higher order-solutions can be found by iterative integration within this class of functions.

  3. Large mass expansion in two-loop QCD corrections of para-charmonium decay

    CERN Document Server

    Hasegawa, K; Pak, Alexey

    2006-01-01

    We calculate the light-by-light scattering type two-loop QCD corrections due to the light quark loops in the para-charmonium decays $eta_{c} rightarrow gamma gamma$ and $eta_{c} rightarrow g g$. We replace the mass of the internal charm quarks by an artificial large mass and obtain the result as a series in the large mass. The obtained series can be transformed into the good convergent ones by a change of the expansion parameter. The results are supported by two other methods to improve the convergence. We also observe that the color singlet state of $eta_{c}$ eliminates the potential divergences in the two-loop QCD corrections. The obtained corrections to the modes $eta_{c} rightarrow gamma gamma$ and $eta_{c} rightarrow g g$ account for -1.25% and -0.73% of the tree level values, respectively. Comparing the ratio of the decay rates with the experimental value, we find the constrains on the unknown contribution to these decays.

  4. Momentum-dependent two-loop QCD corrections to the neutral Higgs-boson masses in the MSSM

    Energy Technology Data Exchange (ETDEWEB)

    Borowka, S.; Hahn, T.; Heinrich, G.; Hollik, W. [Max-Planck-Institut fuer Physik (Werner-Heisenberg-Institut), Munich (Germany); Heinemeyer, S. [Instituto de Fisica de Cantabria (CSIC-UC), Santander (Spain)

    2014-08-15

    Results are presented for the momentum-dependent two-loop contributions of O(α{sub t}α{sub s}) to the masses and mixing effects in the Higgs sector of the MSSM. They are obtained in the Feynman-diagrammatic approach using a mixed on-shell/DR renormalization that can directly be matched onto the higher-order corrections included in the code FeynHiggs. The new two-loop diagrams are evaluated with the program SecDec. The combination of the new momentum-dependent two-loop contribution with the existing one- and two-loop corrections in the on-shell/DR scheme leads to an improved prediction of the light MSSM Higgs boson mass and a correspondingly reduced theoretical uncertainty. We find that the corresponding shifts in the lightest Higgs-boson mass M{sub h} are below 1 GeV in all scenarios considered, but they can extend up to the level of the current experimental uncertainty. The results are included in the code FeynHiggs. (orig.)

  5. Two-loop corrections to the $\\rho$ parameter in Two-Higgs-Doublet Models

    CERN Document Server

    Hessenberger, Stephan

    2016-01-01

    Models with two scalar doublets are among the simplest extensions of the Standard Model which fulfill the relation $\\rho = 1$ at lowest order for the $\\rho$ parameter as favored by experimental data for electroweak observables allowing only small deviations from unity. Such small deviations $\\Delta\\rho$ originate exclusively from quantum effects with special sensitivity to mass splittings between different isospin components of fermions and scalars. In this paper the dominant two-loop electroweak corrections to $\\Delta\\rho$ are calculated in the $CP$-conserving THDM, resulting from the top-Yukawa coupling and the self-couplings of the Higgs bosons in the gauge-less limit. The on-shell renormalization scheme is applied. With the assumption that one of the $CP$-even neutral scalars represents the scalar boson observed by the LHC experiments, with standard properties, the two-loop non-standard contributions in $\\Delta\\rho$ can be separated from the standard ones. These contributions are of particular interest si...

  6. Constraints on abelian extensions of the Standard Model from two-loop vacuum stability and U(1){sub B−L}

    Energy Technology Data Exchange (ETDEWEB)

    Corianò, Claudio [STAG Research Centre and Mathematical Sciences,University of Southampton, Southampton SO17 1BJ (United Kingdom); Dipartimento di Matematica e Fisica “Ennio De Giorgi' ,Università del Salento and INFN - Sezione di Lecce,Via Arnesano, 73100 Lecce (Italy); Rose, Luigi Delle; Marzo, Carlo [Dipartimento di Matematica e Fisica “Ennio De Giorgi' ,Università del Salento and INFN - Sezione di Lecce,Via Arnesano, 73100 Lecce (Italy)

    2016-02-19

    We present a renormalization group study of the scalar potential in a minimal U(1){sub B−L} extension of the Standard Model involving one extra heavier Higgs and three heavy right-handed neutrinos with family universal B-L charge assignments. We implement a type-I seesaw for the masses of the light neutrinos of the Standard Model. In particular, compared to a previous study, we perform a two-loop extension of the evolution, showing that two-loop effects are essential for the study of the stability of the scalar potential up to the Planck scale. The analysis includes the contribution of the kinetic mixing between the two abelian gauge groups, which is radiatively generated by the evolution, and the one-loop matching conditions at the electroweak scale. By requiring the stability of the potential up to the Planck mass, significant constraints on the masses of the heavy neutrinos, on the gauge couplings and the mixing in the Higgs sector are identified.

  7. Taming the Goldstone contributions to the effective potential

    Energy Technology Data Exchange (ETDEWEB)

    Martin, Stephen P. [Fermilab

    2014-07-28

    The standard perturbative effective potential suffers from two related problems of principle involving the field-dependent Goldstone boson squared mass, G. First, in general G can be negative, and it actually is negative in the Standard Model; this leads to imaginary contributions to the effective potential that are not associated with a physical instability, and therefore spurious. Second, in the limit that G approaches zero, the effective potential minimization condition is logarithmically divergent already at two-loop order, and has increasingly severe power-law singularities at higher loop orders. I resolve both issues by resumming the Goldstone boson contributions to the effective potential. For the resulting resummed effective potential, the minimum value and the minimization condition that gives the vacuum expectation value are obtained in forms that do not involve G at all.

  8. Thermodynamics and phase transition of the O(N) model from the two-loop Phi-derivable approximation

    CERN Document Server

    Markó, Gergely; Szép, Zsolt

    2013-01-01

    We discuss the thermodynamics of the O(N) model across the corresponding phase transition using the two-loop Phi-derivable approximation of the effective potential and compare our results to those obtained in the literature within the Hartree-Fock approximation. In particular, we find that in the chiral limit the transition is of the second order, whereas it was found to be of the first order in the Hartree-Fock case. These features are manifest at the level of the thermodynamical observables. We also compute the thermal sigma and pion masses from the curvature of the effective potential. In the chiral limit, this guarantees that the Goldstone theorem is obeyed in the broken phase. A realistic parametrization of the model in the N=4 case, based on the vacuum values of the curvature masses, shows that a sigma mass of around 450 MeV can be obtained. The equations are renormalized after extending our previous results for the N=1 case by means of the general procedure described in [J. Berges et al., Annals Phys. ...

  9. $K_{l4}$ at two-loops and CHPT predictions for $\\pi\\pi$-scattering

    CERN Document Server

    Amorós, G; Talavera, P; Amoros, Gabriel; Bijnens, Johan; Talavera, Pere

    2000-01-01

    We present the results from our two-loop calculations of masses, decay-constants, vacuum-expectation-values and the $K_{\\ell4}$ form-factors in three-flavour Chiral Perturbation Theory (CHPT). We use this to fit the $L_i^r$ to two-loops and discuss the ensuing predictions for $\\pi\\pi$-threshold parameters.

  10. Turbulent magnetic Prandtl number in kinematic magnetohydrodynamic turbulence: two-loop approximation.

    Science.gov (United States)

    Jurčišinová, E; Jurčišin, M; Remecký, R

    2011-10-01

    The turbulent magnetic Prandtl number in the framework of the kinematic magnetohydrodynamic (MHD) turbulence, where the magnetic field behaves as a passive vector field advected by the stochastic Navier-Stokes equation, is calculated by the field theoretic renormalization group technique in the two-loop approximation. It is shown that the two-loop corrections to the turbulent magnetic Prandtl number in the kinematic MHD turbulence are less than 2% of its leading order value (the one-loop value) and, at the same time, the two-loop turbulent magnetic Prandtl number is the same as the two-loop turbulent Prandtl number obtained in the corresponding model of a passively advected scalar field. The dependence of the turbulent magnetic Prandtl number on the spatial dimension d is investigated and the source of the smallness of the two-loop corrections for spatial dimension d=3 is identified and analyzed.

  11. Experimental Study of Flexible Plate Vibration Control by Using Two-Loop Sliding Mode Control Strategy

    Science.gov (United States)

    Yang, Jingyu; Lin, Jiahui; Liu, Yuejun; Yang, Kang; Zhou, Lanwei; Chen, Guoping

    2016-06-01

    It is well known that intelligent control theory has been used in many research fields, novel modeling method (DROMM) is used for flexible rectangular active vibration control, and then the validity of new model is confirmed by comparing finite element model with new model. In this paper, taking advantage of the dynamics of flexible rectangular plate, a two-loop sliding mode (TSM) MIMO approach is introduced for designing multiple-input multiple-output continuous vibration control system, which can overcome uncertainties, disturbances or unstable dynamics. An illustrative example is given in order to show the feasibility of the method. Numerical simulations and experiment confirm the effectiveness of the proposed TSM MIMO controller.

  12. Experimental Study of Flexible Plate Vibration Control by Using Two-Loop Sliding Mode Control Strategy

    Science.gov (United States)

    Yang, Jingyu; Lin, Jiahui; Liu, Yuejun; Yang, Kang; Zhou, Lanwei; Chen, Guoping

    2017-08-01

    It is well known that intelligent control theory has been used in many research fields, novel modeling method (DROMM) is used for flexible rectangular active vibration control, and then the validity of new model is confirmed by comparing finite element model with new model. In this paper, taking advantage of the dynamics of flexible rectangular plate, a two-loop sliding mode (TSM) MIMO approach is introduced for designing multiple-input multiple-output continuous vibration control system, which can overcome uncertainties, disturbances or unstable dynamics. An illustrative example is given in order to show the feasibility of the method. Numerical simulations and experiment confirm the effectiveness of the proposed TSM MIMO controller.

  13. Resummation of Goldstone boson contributions to the MSSM effective potential

    CERN Document Server

    Kumar, Nilanjana

    2016-01-01

    We discuss the resummation of the Goldstone boson contributions to the effective potential of the Minimal Supersymmetric Standard Model (MSSM). This eliminates the formal problems of spurious imaginary parts and logarithmic singularities in the minimization conditions when the tree-level Goldstone boson squared masses are negative or approach zero. The numerical impact of the resummation is shown to be almost always very small. We also show how to write the two-loop minimization conditions so that Goldstone boson squared masses do not appear at all, and so that they can be solved without iteration.

  14. Resummation of Goldstone boson contributions to the MSSM effective potential

    Science.gov (United States)

    Kumar, Nilanjana; Martin, Stephen P.

    2016-07-01

    We discuss the resummation of the Goldstone boson contributions to the effective potential of the minimal supersymmetric Standard Model. This eliminates the formal problems of spurious imaginary parts and logarithmic singularities in the minimization conditions when the tree-level Goldstone boson squared masses are negative or approach zero. The numerical impact of the resummation is shown to be almost always very small. We also show how to write the two-loop minimization conditions so that Goldstone boson squared masses do not appear at all, and so that they can be solved without iteration.

  15. 2D Quantum Gravity on Compact Riemann Surfaces and Two-Loop Partition Function: Circumventing the c=1 Barrier?

    CERN Document Server

    Bilal, Adel

    2014-01-01

    We study two-dimensional quantum gravity on arbitrary genus Riemann surfaces in the Kaehler formalism where the basic quantum field is the (Laplacian of the) Kaehler potential. We do a careful first-principles computation of the fixed-area partition function $Z[A]$ up to and including all two-loop contributions. This includes genuine two-loop diagrams as determined by the Liouville action, one-loop diagrams resulting from the non-trivial measure on the space of metrics, as well as one-loop diagrams involving various counterterm vertices. Contrary to what is often believed, several such counterterms, in addition to the usual cosmological constant, do and must occur. We consistently determine the relevant counterterms from a one-loop computation of the full two-point Green's function of the Kaehler field. Throughout this paper we use the general spectral cutoff regularization developed recently and which is well-suited for multi-loop computations on curved manifolds. At two loops, while all "unwanted" contribut...

  16. Two-loop Prediction for Scaling Exponents in $(2 + \\epsilon)$-dimensional Quantum Gravity

    CERN Document Server

    Aida, T; Aida, Toshiaki; Kitazawa, Yoshihisa

    1996-01-01

    We perform the two loop level renormalization of quantum gravity in $2+\\epsilon$ dimensions. We work in the background gauge whose manifest covariance enables us to use the short distance expansion of the Green's functions. We explicitly show that the theory is renormalizable to the two loop level in our formalism. We further make a physical prediction for the scaling relation between the gravitational coupling constant and the cosmological constant which is expected to hold at the short distance fixed point of the renormalization group. It is found that the two loop level calculation is necessary to determine the scaling exponent to the leading order in $\\epsilon$.

  17. Two loop computation of a running coupling in lattice Yang-Mills theory

    CERN Document Server

    Narayanan, R A; Narayanan, Rajamani; Wolff, Ulli

    1995-01-01

    We compute the two loop coefficient in the relation between the lattice bare coupling and the running coupling defined through the Schroedinger functional for the case of pure SU(2) gauge theory. This result is needed as one computational component to relate the latter to the MSbar-coupling, and it allows us to implement O(a) improvement of the Schroedinger functional to two-loop order. In addition, the two-loop beta-function is verified in a perturbative computation on the lattice, and the behavior of an improved bare coupling is investigated beyond one loop.

  18. The two-loop electroweak bosonic corrections to $\\sin^2\\theta_{\\rm eff}^{\\rm b}$

    CERN Document Server

    Dubovyk, Ievgen; Gluza, Janusz; Riemann, Tord; Usovitsch, Johann

    2016-01-01

    The prediction of the effective electroweak mixing angle $\\sin^2\\theta_{\\rm eff}^{\\rm b}$ in the Standard Model at two-loop accuracy has now been completed by the first calculation of the bosonic two-loop corrections to the $Z{\\bar b}b$ vertex. Numerical predictions are presented in the form of a fitting formula as function of $M_Z, M_W, M_H, m_t$ and $\\Delta{\\alpha}$, ${\\alpha_{\\rm s}}$. For central input values, we obtain a relative correction of $\\Delta\\kappa_{\\rm b}^{(\\alpha^2,\\rm bos)} = -0.9855 \\times 10^{-4}$, amounting to about a quarter of the fermionic corrections, and corresponding to $\\sin^2\\theta_{\\rm eff}^{\\rm b} = 0.232704$. The integration of the corresponding two-loop vertex Feynman integrals with up to three dimensionless parameters in Minkowskian kinematics has been performed with two approaches: (i) Sector decomposition, implemented in the packages FIESTA 3 and SecDec 3, and (ii) Mellin-Barnes representations, implemented in AMBRE 3/MB and the new package MBnumerics.

  19. A Two-loop Test of Buscher's T-duality, 1

    CERN Document Server

    Horváth, Z; Palla, L; Horvath, Zalan; Karp, Robert L.; Palla, Laszlo

    2000-01-01

    We study the two loop quantum equivalence of sigma models related by Buscher's T-duality transformation. The computation of the two loop perturbative free energy density is performed in the case of a certain deformation of the SU(2) principal sigma model, and its T-dual, using dimensional regularization and the geometric sigma model perturbation theory. We obtain agreement between the free energy density expressions of the two models.

  20. Two-loop supersymmetric QCD and half-maximal supergravity amplitudes

    Science.gov (United States)

    Johansson, Henrik; Kälin, Gregor; Mogull, Gustav

    2017-09-01

    Using the duality between color and kinematics, we construct two-loop four-point scattering amplitudes in N=2 super-Yang-Mills (SYM) theory coupled to N f fundamental hypermultiplets. Our results are valid in D ≤ 6 dimensions, where the upper bound corresponds to six-dimensional chiral N=(1,0) SYM theory. By exploiting a close connection with N=4 SYM theory — and, equivalently, six-dimensional N=(1,1) SYM theory — we find compact integrands with four-dimensional external vectors in both the maximally-helicity-violating (MHV) and all-chiral-vector sectors. Via the double-copy construction corresponding D-dimensional half-maximal supergravity amplitudes with external graviton multiplets are obtained in the MHV and all-chiral sectors. Appropriately tuning N f enables us to consider both pure and matter-coupled supergravity, with arbitrary numbers of vector multiplets in D = 4. As a bonus, we obtain the integrands of the genuinely six-dimensional supergravities with N=(1,1) and N=(2,0) supersymmetry. Finally, we extract the potential ultraviolet divergence of half-maximal supergravity in D = 5 - 2 ɛ and show that it non-trivially cancels out as expected.

  1. Systematics of High Temperature Perturbation Theory: The Two-Loop Electron Self-Energy in QED

    CERN Document Server

    Mottola, Emil; 10.1103/PhysRevD.81.025014

    2010-01-01

    In order to investigate the systematics of the loop expansion in high temperature gauge theories beyond the leading order hard thermal loop (HTL) approximation, we calculate the two-loop electron proper self-energy in high temperature QED. The two-loop bubble diagram contains a linear infrared divergence. Even if regulated with a non-zero photon mass M of order of the Debye mass, this infrared sensitivity implies that the two-loop self-energy contributes terms to the fermion dispersion relation that are comparable to or even larger than the next-to-leading-order (NLO) contributions at one-loop. Additional evidence for the necessity of a systematic restructuring of the loop expansion comes from the explicit gauge parameter dependence of the fermion damping rate at both one and two-loops. The leading terms in the high temperature expansion of the two-loop self-energy for all topologies arise from an explicit hard-soft factorization pattern, in which one of the loop integrals is hard, nested inside a second loop...

  2. On effective Kähler potential in N=2, d=3 SQED

    Directory of Open Access Journals (Sweden)

    I.L. Buchbinder

    2015-11-01

    Full Text Available We compute the two-loop effective Kähler potential in three-dimensional N=2 supersymmetric electrodynamics with Chern–Simons kinetic term for the gauge superfield. The effective action is constructed on the base of background field method with one parametric family of gauges. In such an approach, the quadratic part of quantum action mixes the gauge and matter quantum superfields yielding the complications in the computations of the loop supergraphs. To avoid this obstacle and preserve dependence on the gauge parameter we make a non-local change of quantum matter superfields after which the propagator is diagonalized, however the new vertices have appeared. We fix the suitable background and develop the efficient procedure of calculating the two-loop supergraphs with the new vertices. We compute the divergent and finite parts of the superfield effective action, find the two-loop effective Kähler potential and show that it does not depend on the gauge parameter.

  3. Two-loop conformal generators for leading-twist operators in QCD

    Energy Technology Data Exchange (ETDEWEB)

    Braun, V.M.; Strohmaier, M. [Regensburg Univ. (Germany). Inst. fuer Theoretische Physik; Manashov, A.N. [Regensburg Univ. (Germany). Inst. fuer Theoretische Physik; Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik; Moch, S. [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik

    2016-01-15

    QCD evolution equations in minimal subtraction schemes have a hidden symmetry: One can construct three operators that commute with the evolution kernel and form an SL(2) algebra, i.e. they satisfy (exactly) the SL(2) commutation relations. In this paper we find explicit expressions for these operators to two-loop accuracy going over to QCD in non-integer d=4-2ε space-time dimensions at the intermediate stage. In this way conformal symmetry of QCD is restored on quantum level at the specially chosen (critical) value of the coupling, and at the same time the theory is regularized allowing one to use the standard renormalization procedure for the relevant Feynman diagrams. Quantum corrections to conformal generators in d=4-2ε effectively correspond to the conformal symmetry breaking in the physical theory in four dimensions and the SL(2) commutation relations lead to nontrivial constraints on the renormalization group equations for composite operators. This approach is valid to all orders in perturbation theory and the result includes automatically all terms that can be identified as due to a nonvanishing QCD β-function (in the physical theory in four dimensions). Our result can be used to derive three-loop evolution equations for flavor-nonsinglet quark-antiquark operators including mixing with the operators containing total derivatives. These equations govern, e.g., the scale dependence of generalized hadron parton distributions and light-cone meson distribution amplitudes.

  4. Two-Loop Beam and Soft Functions for Rapidity-Dependent Jet Vetoes

    CERN Document Server

    Gangal, Shireen; Stahlhofen, Maximilian; Tackmann, Frank J

    2016-01-01

    Jet vetoes play an important role in many analyses at the LHC. Traditionally, jet vetoes have been imposed using a restriction on the transverse momentum $p_{Tj}$ of jets. Alternatively, one can also consider jet observables for which $p_{Tj}$ is weighted by a smooth function of the jet rapidity $y_j$ that vanishes as $|y_j| \\to \\infty$. Such observables are useful as they provide a natural way to impose a tight veto on central jets but a looser one at forward rapidities. We consider two such rapidity-dependent jet veto observables, $\\mathcal{T}_{Bj}$ and $\\mathcal{T}_{Cj}$, and compute the required beam and dijet soft functions for the jet-vetoed color-singlet production cross section at two loops. At this order, clustering effects from the jet algorithm become important. The dominant contributions are computed fully analytically while corrections that are subleading in the limit of small jet radii are expressed in terms of finite numerical integrals. Our results enable the full NNLL' resummation and are an ...

  5. Naturalness made easy: two-loop naturalness bounds on minimal SM extensions

    CERN Document Server

    Clarke, Jackson D

    2016-01-01

    The main result of this paper is a collection of conservative naturalness bounds on minimal extensions of the standard model by (vector-like) fermionic or scalar gauge multiplets. Within, we advocate for an intuitive and physical concept of naturalness built upon the renormalisation group equations. In the effective field theory of the standard model plus a gauge multiplet with mass $M$, the low scale Higgs mass parameter is a calculable function of $\\overline{\\rm MS}$ input parameters defined at some high scale $\\Lambda_h > M$. If the Higgs mass is very sensitive to these input parameters, then this signifies a naturalness problem. To sensibly capture the sensitivity, it is shown how a sensitivity measure can be rigorously derived as a Bayesian model comparison, which reduces in a relevant limit to a Barbieri--Giudice-like fine-tuning measure. This measure is fully generalisable to any perturbative EFT. The interesting results of our two-loop renormalisation group study are as follows: for $\\Lambda_h=\\Lambda...

  6. Naturalness made easy: two-loop naturalness bounds on minimal SM extensions

    Science.gov (United States)

    Clarke, Jackson D.; Cox, Peter

    2017-02-01

    The main result of this paper is a collection of conservative naturalness bounds on minimal extensions of the Standard Model by (vector-like) fermionic or scalar gauge multiplets. Within, we advocate for an intuitive and physical concept of naturalness built upon the renormalisation group equations. In the effective field theory of the Standard Model plus a gauge multiplet with mass M , the low scale Higgs mass parameter is a calculable function of overline{MS} input parameters defined at some high scale Λ h > M . If the Higgs mass is very sensitive to these input parameters, then this signifies a naturalness problem. To sensibly capture the sensitivity, it is shown how a sensitivity measure can be rigorously derived as a Bayesian model comparison, which reduces in a relevant limit to a Barbieri-Giudice-like fine-tuning measure. This measure is fully generalisable to any perturbative EFT. The interesting results of our two-loop renormalisation group study are as follows: for Λ h = ΛPl we find "10% fine-tuning" bounds on the masses of various gauge multiplets of M

  7. The Hubble effective potential

    Energy Technology Data Exchange (ETDEWEB)

    Janssen, T.M.; Miao, S.P.; Prokopec, T. [Institute for Theoretical Physics and Spinoza Institute, Utrecht University, Leuvenlaan 4, Postbus 80.195, 3508 TD Utrecht (Netherlands); Woodard, R.P., E-mail: T.M.Janssen@uu.nl, E-mail: S.Miao@uu.nl, E-mail: T.Prokopec@uu.nl, E-mail: woodard@phys.ufl.edu [Department of Physics, University of Florida, Gainesville, FL 32611 (United States)

    2009-05-15

    We generalize the effective potential to scalar field configurations which are proportional to the Hubble parameter of a homogeneous and isotropic background geometry. This may be useful in situations for which curvature effects are significant. We evaluate the one loop contribution to the Hubble Effective Potential for a massless scalar with arbitrary conformal and quartic couplings, on a background for which the deceleration parameter is constant. Among other things, we find that inflationary particle production leads to symmetry restoration at late times.

  8. Two-loop electroweak threshold corrections to the bottom and top Yukawa couplings

    CERN Document Server

    Kniehl, Bernd A

    2014-01-01

    We study the relationship between the MS-bar Yukawa coupling and the pole mass for the bottom and top quarks at the two-loop electroweak order O(alpha^2) in the gaugeless limit of the standard model. We also consider the MS-bar to pole mass relationships at this order, which include tadpole contributions to ensure the gauge independence of the MS-bar masses. In order to avoid the presence of tadpoles, we propose a redefinition of the running heavy-quark mass in terms of the MS-bar Yukawa coupling. We also present Delta r in the MS-bar scheme at O(alpha^2) in the gaugeless limit. As an aside, we also present the exact two-loop expression for the heavy-quark mass counterterm at two loops.

  9. FDR, an easier way to NNLO calculations: a two-loop case study

    CERN Document Server

    Donati, Alice Maria

    2013-01-01

    In this paper we advertise the important simplifications produced by FDR in NNLO computations. We show that - due to its four-dimensionality - FDR does not require an order-by-order renormalization and that, unlike the one-loop case, FDR and dimensional regularization (DR) generate intermediate two-loop results which are no longer linked by a simple subtraction of the ultraviolet (UV) poles in epsilon. As an illustrative example, we re-derive the known two-loop result for H -> gamma gamma mediated by an infinitely heavy top loop in the presence of gluonic corrections. The calculation establishes FDR as a simpler and fully consistent approach to the UV problem at the two-loop level, that, in turn, is an essential ingredient toward purely numerical NNLO calculations.

  10. Two-loop renormalization of scalar and pseudoscalar fermion bilinears on the lattice

    Science.gov (United States)

    Skouroupathis, A.; Panagopoulos, H.

    2007-11-01

    We compute the two-loop renormalization functions, in the RI' scheme, of local bilinear quark operators ψ¯Γψ, where Γ denotes the scalar and pseudoscalar Dirac matrices, in the lattice formulation of QCD. We consider both the flavor nonsinglet and singlet operators; the latter, in the scalar case, leads directly to the two-loop fermion mass renormalization, Zm. As a prerequisite for the above, we also compute the quark field renormalization, Zψ, up to two loops. We use the clover action for fermions and the Wilson action for gluons. Our results are given as a polynomial in cSW, in terms of both the renormalized and bare coupling constants, in the renormalized Feynman gauge. We also confirm the one-loop renormalization functions, for generic gauge. Finally, we present our results in the MS¯ scheme, for easier comparison with calculations in the continuum. The corresponding results, for fermions in an arbitrary representation, are included in the Appendix.

  11. Two-loop renormalization of scalar and pseudoscalar fermion bilinears on the lattice

    CERN Document Server

    Skouroupathis, A

    2007-01-01

    We compute the two-loop renormalization functions, in the RI $^\\prime$ scheme, of local bilinear quark operators $\\bar{\\psi}\\Gamma\\psi$, where $\\Gamma$ denotes the Scalar and Pseudoscalar Dirac matrices, in the lattice formulation of QCD. We consider both the flavor non-singlet and singlet operators; the latter, in the scalar case, leads directly to the two-loop fermion mass renormalization, $Z_m$. As a prerequisite for the above, we also compute the quark field renormalization, $Z_{\\psi}$, up to two loops. We use the clover action for fermions and the Wilson action for gluons. Our results are given as a polynomial in $c_{SW}$, in terms of both the renormalized and bare coupling constant, in the renormalized Feynman gauge. We also confirm the 1-loop renormalization functions, for generic gauge. Finally, we present our results in the $\\bar{MS}$ scheme, for easier comparison with calculations in the continuum.

  12. Two-loop renormalization in the standard model, part I. Prolegomena

    Energy Technology Data Exchange (ETDEWEB)

    Actis, S. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Ferroglia, A. [Albert-Ludwigs-Univ., Freiburg (Germany). Fakultat fur Phys.]|[Zuerich Univ. (Switzerland). Inst. fuer Theoretische Physik; Passera, M. [Padua Univ. (Italy). Dipt. di Fisica]|[INFN, Sezione di Padova (Italy); Passarino, G. [Torino Univ. (Italy). Dipt. di Fisica Teorica]|[INFN, Sezione di Torino (Italy)

    2006-12-15

    In this paper the building blocks for the two-loop renormalization of the Standard Model are introduced with a comprehensive discussion of the special vertices induced in the Lagrangian by a particular diagonalization of the neutral sector and by two alternative treatments of the Higgs tadpoles. Dyson resummed propagators for the gauge bosons are derived, and two-loop Ward-Slavnov-Taylor identities are discussed. In part II, the complete set of counterterms needed for the two-loop renormalization will be derived. In part III, a renormalization scheme will be introduced, connecting the renormalized quantities to an input parameter set of (pseudo-)experimental data, critically discussing renormalization of a gauge theory with unstable particles. (orig.)

  13. Two-loop QCD Correction to Massive Spin-2 Resonance $ \\to q ~ \\bar{q} ~ g $

    CERN Document Server

    Ahmed, Taushif; Mathews, Prakash; Rana, Narayan; Ravindran, V

    2016-01-01

    Two-loop QCD correction to massive spin-2 Graviton decaying to $q ~ + ~ \\bar{q}~ + ~g$ is presented considering a generic universal spin-2 coupling to the SM through the conserved energy-momentum tensor. Such a massive spin-2 particle can arise in extra-dimensional models. The ultraviolet and infrared structure of the QCD amplitudes are studied. In dimensional regularisation, the infrared pole structure is in agreement with Catani's proposal, confirming the universal factorization property of QCD amplitudes, even with the spin-2 tensorial coupling. This computation now completes the full two-loop QCD corrections for the production of a spin-2 in association with a jet.

  14. The Vector and Scalar Form Factors of the Pion to Two Loops

    CERN Document Server

    Bijnens, J; Talavera, P

    1998-01-01

    We calculate the vector and scalar form factors of the pion to two loops in Chiral Perturbation Theory. We estimate the unknown O(p^6) constants using resonance exchange. We make a careful comparison to the available data and determine two O(p^4) constants rather precisely, and two O(p^6) constants less precisely. We also use Chiral Perturbation Theory to two loops to extract in a model--independent manner the charge radius of the pion from the available data, and obtain \\rpiV=0.437\\pm 0.016 fm^2.

  15. The Inverse Amplitude Method in $\\pi\\pi$ Scattering in Chiral Perturbation Theory to Two Loops

    CERN Document Server

    Nieves, J; Ruiz-Arriola, E

    2002-01-01

    The inverse amplitude method is used to unitarize the two loop $\\pi\\pi$ scattering amplitudes of SU(2) Chiral Perturbation Theory in the $I=0,J=0$, $I=1,J=1$ and $I=2,J=0$ channels. An error analysis in terms of the low energy one-loop parameters $\\bar l_{1,2,3,4,}$ and existing experimental data is undertaken. A comparison to standard resonance saturation values for the two loop coefficients $\\bar b_{1,2,3,4,5,6} $ is also carried out. Crossing violations are quantified and the convergence of the expansion is discussed.

  16. Sfermion loop contribution to the two-loop level fermion electric dipole moment in R-parity violating supersymmetric models

    CERN Document Server

    Yamanaka, Nodoka

    2012-01-01

    We evaluate the Barr-Zee type two-loop level contribution to the fermion electric and chromo-electric dipole moments with sfermion loop in R-parity violating supersymmetric models. It is found that the Barr-Zee type fermion dipole moment with sfermion loop acts destructively to the currently known fermion loop contribution, and that it has small effect when the mass of squarks or charged sleptons in the loop is larger than or comparable to that of the sneutrinos, but cannot be neglected if the sneutrinos are much heavier than loop sfermions.

  17. Renormalization of two-loop diagrams in scalar lattice field theory

    CERN Document Server

    Borasoy, B

    2006-01-01

    We present a method to calculate to very high precision the coefficients of the divergences occuring in two-loop diagrams for a massive scalar field on the lattice. The approach is based on coordinate space techniques and extensive use of the precisely known Green's function.

  18. The two-loop six-point amplitude in ABJM theory

    CERN Document Server

    Huang, Yu-tin

    2012-01-01

    In this paper we present the first analytic computation of the six-point two-loop amplitude of ABJM theory. We show that the two-loop amplitude consist of corrections proportional to two distinct local Yangian invariants which can be identified as the tree- and the one-loop amplitude respectively. The two-loop correction proportional to the tree-amplitude is identical to the one-loop BDS result of N=4 SYM plus an additional remainder function, while the correction proportional to the one-loop amplitude is finite. Both the remainder and the finite correction are dual conformal invariant, which implies that the two-loop dual conformal anomaly equation for ABJM is again identical to that of one-loop N=4 SYM, as was first observed at four-point. We discuss the theory on the Higgs branch, showing that its amplitudes are infrared finite, but equal, in the small mass limit, to those obtained in dimensional regularization.

  19. Two-loop RG functions of the massive φ4 field theory in general dimensions

    Directory of Open Access Journals (Sweden)

    M.A. Shpot

    2010-01-01

    Full Text Available Two-loop Feynman integrals of the massive φ4d field theory are explicitly obtained for generic space dimensions d. Corresponding renormalization-group functions are expressed in a compact form in terms of Gauss hypergeometric functions. A number of interesting and useful relations are given for these integrals as well as for several special mathematical functions and constants.

  20. Two-loop Bhabha scattering at high energy beyond leading power approximation

    Directory of Open Access Journals (Sweden)

    Alexander A. Penin

    2016-09-01

    Full Text Available We evaluate the two-loop O(me2/s contribution to the wide-angle high-energy electron–positron scattering in the double-logarithmic approximation. The origin and the general structure of the power-suppressed double logarithmic corrections are discussed in detail.

  1. PyR@TE 2: A Python tool for computing RGEs at two-loop

    Science.gov (United States)

    Lyonnet, F.; Schienbein, I.

    2017-04-01

    Renormalization group equations are an essential tool for the description of theories across different energy scales. Even though their expressions at two-loop for an arbitrary gauge field theory have been known for more than thirty years, deriving the full set of equations for a given model by hand is very challenging and prone to errors. To tackle this issue, we have introduced in Lyonnet et al. (2014) a Python tool called PyR@TE; Python Renormalization group equations @ Two-loop for Everyone. With PyR@TE, it is easy to implement a given Lagrangian and derive the complete set of two-loop RGEs for all the parameters of the theory. In this paper, we present the new version of this code, PyR@TE 2, which brings many new features and in particular it incorporates kinetic mixing when several U(1) gauge groups are involved. In addition, the group theory part has been greatly improved as we introduced a new Python module dubbed PyLie that deals with all the group theoretical aspects required for the calculation of the RGEs as well as providing very useful model building capabilities. This allows the use of any irreducible representation of the SU(n) , SO(2 n) and SO(2n + 1) groups. Furthermore, it is now possible to implement terms in the Lagrangian involving fields which can be contracted into gauge singlets in more than one way. As a byproduct, results for a popular model (SM + complex triplet) for which, to our knowledge, the complete set of two-loop RGEs has not been calculated before are presented in this paper. Finally, the two-loop RGEs for the anomalous dimension of the scalar and fermion fields have been implemented as well. It is now possible to export the coupled system of beta functions into a numerical C++ function, leading to a consequent speed up in solving them.

  2. Two-loop controller for maximizing performance of a grid-connected photovoltaic - fuel cell hybrid power plant

    Science.gov (United States)

    Ro, Kyoungsoo

    The study started with the requirement that a photovoltaic (PV) power source should be integrated with other supplementary power sources whether it operates in a stand-alone or grid-connected mode. First, fuel cells for a backup of varying PV power were compared in detail with batteries and were found to have more operational benefits. Next, maximizing performance of a grid-connected PV-fuel cell hybrid system by use of a two-loop controller was discussed. One loop is a neural network controller for maximum power point tracking, which extracts maximum available solar power from PV arrays under varying conditions of insolation, temperature, and system load. A real/reactive power controller (RRPC) is the other loop. The RRPC meets the system's requirement for real and reactive powers by controlling incoming fuel to fuel cell stacks as well as switching control signals to a power conditioning subsystem. The RRPC is able to achieve more versatile control of real/reactive powers than the conventional power sources since the hybrid power plant does not contain any rotating mass. Results of time-domain simulations prove not only effectiveness of the proposed computer models of the two-loop controller, but also their applicability for use in transient stability analysis of the hybrid power plant. Finally, environmental evaluation of the proposed hybrid plant was made in terms of plant's land requirement and lifetime COsb2 emissions, and then compared with that of the conventional fossil-fuel power generating forms.

  3. BPS Wilson loops and Bremsstrahlung function in ABJ(M): a two loop analysis

    Energy Technology Data Exchange (ETDEWEB)

    Bianchi, Marco S. [Institut für Physik, Humboldt-Universität zu Berlin,Newtonstraße 15, 12489 Berlin (Germany); Griguolo, Luca [Dipartimento di Fisica e Scienze della Terra, Università di Parmaand INFN Gruppo Collegato di Parma,Viale G.P. Usberti 7/A, 43100 Parma (Italy); Leoni, Matias [Physics Department, FCEyN-UBA & IFIBA-CONICETCiudad Universitaria, Pabellón I, 1428, Buenos Aires (Argentina); Penati, Silvia [Dipartimento di Fisica, Università di Milano-Bicoccaand INFN, Sezione di Milano-Bicocca,Piazza della Scienza 3, I-20126 Milano (Italy); Seminara, Domenico [Dipartimento di Fisica, Università di Firenzeand INFN Sezione di Firenze,via G. Sansone 1, 50019 Sesto Fiorentino (Italy)

    2014-06-19

    We study a family of circular BPS Wilson loops in N=6 super Chern-Simons-matter theories, generalizing the usual 1/2-BPS circle. The scalar and fermionic couplings depend on two deformation parameters and these operators can be considered as the ABJ(M) counterpart of the DGRT latitudes defined in N=4 SYM. We perform a complete two-loop analysis of their vacuum expectation value, discuss the appearance of framing-like phases and propose a general relation with cohomologically equivalent bosonic operators. We make an all-loop proposal for computing the Bremsstrahlung function associated to the 1/2-BPS cusp in terms of these generalized Wilson loops. When applied to our two-loop result it reproduces the known expression. Finally, we comment on the generalization of this proposal to the bosonic 1/6-BPS case.

  4. Hard Photon production from unsaturated quark gluon plasma at two loop level

    CERN Document Server

    Dutta, D; Mohanty, A K; Kumar, K; Choudhury, R K

    2002-01-01

    The hard photon productions from bremsstrahlung and annihilation with scattering that arise at two loop level are estimated from a chemically non-equilibrated quark gluon plasma using the frame work of thermal field theory. Although, the rate of photon production is suppressed due to unsaturated phase space, the above suppression is relatively smaller than expected due to an additional collinear enhancement (arise due to decrease in thermal quark mass) as compared to it's equilibrium counterpart. Interestingly, unlike the one loop case, the reduction in the two loop processes are found to be independent of gluon chemical poential, but strongly depends on quark fugacity. It is also found that, since the phase space suppression is highest for annihilation with scattering, the photon production is entirely dominated by bremsstrahlung mechanism at all energies. This is to be contrasted with the case of the equilibrated plasma where annihilation with scattering dominates the photon production particularly at highe...

  5. Local Integrand Representations of All Two-Loop Amplitudes in Planar SYM

    CERN Document Server

    Bourjaily, Jacob L

    2015-01-01

    We use generalized unitarity at the integrand-level to directly construct local, manifestly dual-conformally invariant formulae for all two-loop scattering amplitudes in planar, maximally supersymmetric Yang-Mills theory (SYM). This representation separates contributions into manifestly finite and manifestly divergent terms---in a way that renders all infrared-safe observables (including ratio functions) calculable without any need for regulation. These results perfectly match the all-loop BCFW recursion relations, to which we provide a closed-form solution valid through two-loop-order. Finally, we describe and document a Mathematica package which implements these results, available as part of this work's source files on the arXiv.

  6. Two-loop renormalization in the standard model, part III. Renormalization equations and their solutions

    Energy Technology Data Exchange (ETDEWEB)

    Actis, S. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Passarino, G. [Torino Univ. (Italy). Dipt. di Fisica Teorica; INFN, Sezione di Torino (Italy)

    2006-12-15

    In part I and II of this series of papers all elements have been introduced to extend, to two loops, the set of renormalization procedures which are needed in describing the properties of a spontaneously broken gauge theory. In this paper, the final step is undertaken and finite renormalization is discussed. Two-loop renormalization equations are introduced and their solutions discussed within the context of the minimal standard model of fundamental interactions. These equations relate renormalized Lagrangian parameters (couplings and masses) to some input parameter set containing physical (pseudo-)observables. Complex poles for unstable gauge and Higgs bosons are used and a consistent setup is constructed for extending the predictivity of the theory from the Lep1 Z-boson scale (or the Lep2 WW scale) to regions of interest for LHC and ILC physics. (orig.)

  7. Matching the $D^{6}R^{4}$ interaction at two-loops

    CERN Document Server

    D'Hoker, Eric; Pioline, Boris; Russo, Rodolfo

    2015-01-01

    The coefficient of the $D^6 {\\cal R}^4$ interaction in the low energy expansion of the two-loop four-graviton amplitude in type II superstring theory is known to be proportional to the integral of the Zhang-Kawazumi (ZK) invariant over the moduli space of genus-two Riemann surfaces. We demonstrate that the ZK invariant is an eigenfunction with eigenvalue 5 of the Laplace-Beltrami operator in the interior of moduli space. Exploiting this result, we evaluate the integral of the ZK invariant explicitly, finding agreement with the value of the two-loop $D^6 {\\cal R}^4$ interaction predicted on the basis of S-duality and supersymmetry. A review of the current understanding of the $D^{2p} {\\cal R}^4$ interactions in type II superstring theory compactified on a torus $T^d$ with $p \\leq 3$ and $d \\leq 4$ is included.

  8. Two Loop Radiative Seesaw and X-ray line Dark Matter with Global U(1) Symmetry

    CERN Document Server

    Okada, Hiroshi

    2015-01-01

    We study a two loop induced radiative neutrino model with global $U(1)$ symmetry at 0.1 GeV scale, in which we consider a keV scale of dark matter candidate recently reported by XMN-Newton X-ray observatory using data of various galaxy clusters and Andromeda galaxy. We also discuss the vacuum stability of singly charged bosons, lepton flavor violation processes, and a role of Goldstone boson.

  9. Two-Loop Iteration of Five-Point N=4 Super-Yang-Mills Amplitudes

    CERN Document Server

    Bern, Z; Kosower, D A; Roiban, R; Smirnov, V A

    2006-01-01

    We confirm by explicit computation the conjectured all-orders iteration of planar maximally supersymmetric N=4 Yang-Mills theory in the nontrivial case of five-point two-loop amplitudes. We compute the required unitarity cuts of the integrand and evaluate the resulting integrals numerically using a Mellin--Barnes representation and the automated package of ref.~[1]. This confirmation of the iteration relation provides further evidence suggesting that N=4 gauge theory is solvable.

  10. New results for a two-loop massless propagator-type Feynman diagram

    CERN Document Server

    Kotikov, A V

    2016-01-01

    We consider the two-loop massless propagator-type Feynman diagram with an arbitrary (non-integer) index on the central line. We analytically prove the equality of the two well-known results existing in the literature which express this diagram in terms of ${}_3F_2$-hypergeometric functions of argument $-1$ and $1$, respectively. We also derive new representations for this diagram which may be of importance in practical calculations.

  11. Two-loop current-current operator contribution to the non-leptonic QCD penguin amplitude

    CERN Document Server

    Bell, Guido; Huber, Tobias; Li, Xin-Qiang

    2015-01-01

    The computation of direct CP asymmetries in charmless B decays at next-to-next-to-leading order (NNLO) in QCD is of interest to ascertain the short-distance contribution. Here we compute the two-loop penguin contractions of the current-current operators Q_{1,2} and provide a first estimate of NNLO CP asymmetries in penguin-dominated b -> s transitions.

  12. Brief description of the flavor-changing neutral scalar interactions at two-loop level

    CERN Document Server

    Gaitán, R

    2016-01-01

    In this letter we show a general description about flavor-changing neutral currents (FCNC) mediated by scalars. The analysis is extended at two-loop level for the Two-Higgs Doublet Model type-III because others models have strong constraints on its parameters, even at high orders of the perturbation. For this letter we focus on the standard model, calculating the amplitude for the $h \\to \\gamma \\gamma$ process and discussing the results briefly.

  13. Brief description of the flavor-changing neutral scalar interactions at two-loop level

    Science.gov (United States)

    Gaitán, R.; Orduz-Ducuara, J. A.

    2016-10-01

    In this letter we show a general description about flavor-changing neutral currents (FCNC) mediated by scalars. The analysis is extended at two-loop level for the Two-Higgs Doublet Model type-III because others models have strong constraints on its parameters, even at high orders of the perturbation. For this letter we focus on the standard model, calculating the amplitude for the h→γγ process and discussing the results briefly.

  14. Modeling and Simulation of Release of Radiation in Flow Blockage Accident for Two Loops PWR

    OpenAIRE

    Khurram Mehboob; Cao Xinrong; Majid Ali

    2012-01-01

    In this study modeling and simulation of release of radiation form two loops PWR has been carried out for flow blockage accident. For this purpose, a MATLAB based program “Source Term Evaluator for Flow Blockage Accident” (STEFBA) has been developed, which uses the core inventory as its primary input. The TMI-2 reactor is considered as the reference plant for this study. For 1100 reactor operation days, the core inventory has been evaluated under the core design constrains at average reactor ...

  15. Master integrals for massive two-loop Bhabha scattering in QED

    CERN Document Server

    Czakon, M; Riemann, Tord

    2004-01-01

    We present a set of scalar master integrals (MIs) needed for a complete treatment of massive two-loop corrections to Bhabha scattering in QED, including integrals with arbitrary fermionic loops. The status of analytical solutions for the MIs is reviewed and examples of some methods to solve MIs analytically are worked out in more detail. Analytical results for the pole terms in epsilon of so far unknown box MIs with five internal lines are given.

  16. Master integrals for massive two-loop Bhabha scattering in QED

    Energy Technology Data Exchange (ETDEWEB)

    Czakon, M. [Wuerzburg Univ. (Germany). Inst. fuer Theoretische Physik und Astrophysik]|[Uniwersytet Slaski, Katowice (Poland). Inst. Fizyki; Gluza, J. [Uniwersytet Slaski, Katowice (Poland). Inst. Fizyki; Riemann, T.

    2004-12-01

    We present a set of scalar master integrals (MIs) needed for a complete treatment of massive two-loop corrections to Bhabha scattering in QED, including integrals with arbitrary fermionic loops. The status of analytical solutions for the MIs is reviewed and examples of some methods to solve MIs analytically are worked out in more detail. Analytical results for the pole terms in {epsilon} of so far unknown box MIs with five internal lines are given. (orig.)

  17. Two-loop anomalous dimensions for currents of baryons with two heavy quarks in NRQCD

    CERN Document Server

    Kiselev, V V

    1998-01-01

    We present analytical results on the two-loop anomalous dimensions of currents for baryons, containing two heavy quarks $J = [Q^{iT}C\\Gamma\\tau Q^j]\\Gamma' q^k\\epsilon_{ijk}$ with arbitrary Dirac matrices $\\Gamma$ and velocity of heavy quarks and the inverse heavy quark mass. It is shown, that in this approximation the anomalous dimensions do not depend on the Dirac structure of the current under consideration.

  18. Integral Reduction by Unitarity Method for Two-loop Amplitudes: A Case Study

    CERN Document Server

    Feng, Bo; Huang, Rijun; Zhou, Kang

    2014-01-01

    In this paper, we generalize the unitarity method to two-loop diagrams and use it to discuss the integral bases of reduction. To test out method, we focus on the four-point double-box diagram as well as its related daughter diagrams, i.e., the double-triangle diagram and the triangle-box diagram. For later two kinds of diagrams, we have given complete analytical results in general (4-2\\eps)-dimension.

  19. Two-Loop Gluon to Gluon-Gluon Splitting Amplitudes in QCD

    Energy Technology Data Exchange (ETDEWEB)

    Bern, Z.

    2004-04-30

    Splitting amplitudes are universal functions governing the collinear behavior of scattering amplitudes for massless particles. We compute the two-loop g {yields} gg splitting amplitudes in QCD, N = 1, and N = 4 super-Yang-Mills theories, which describe the limits of two-loop n-point amplitudes where two gluon momenta become parallel. They also represent an ingredient in a direct x-space computation of DGLAP evolution kernels at next-to-next-to-leading order. To obtain the splitting amplitudes, we use the unitarity sewing method. In contrast to the usual light-cone gauge treatment, our calculation does not rely on the principal-value or Mandelstam-Leibbrandt prescriptions, even though the loop integrals contain some of the denominators typically encountered in light-cone gauge. We reduce the integrals to a set of 13 master integrals using integration-by-parts and Lorentz invariance identities. The master integrals are computed with the aid of differential equations in the splitting momentum fraction z. The {epsilon}-poles of the splitting amplitudes are consistent with a formula due to Catani for the infrared singularities of two-loop scattering amplitudes. This consistency essentially provides an inductive proof of Catani's formula, as well as an ansatz for previously-unknown 1/{epsilon} pole terms having non-trivial color structure. Finite terms in the splitting amplitudes determine the collinear behavior of finite remainders in this formula.

  20. Two-loop Feynman Diagrams in Yang-Mills Theory from Bosonic String Amplitudes

    CERN Document Server

    Körs, B; Kors, Boris; Schmidt, Michael G.

    2000-01-01

    We present intermediate results of an ongoing investigation which attempts a generalization of the well known one-loop Bern Kosower rules of Yang-Mills theory to higher loop orders. We set up a general procedure to extract the field theoretical limit of bosonic open string diagrams, based on the sewing construction of higher loop world sheets. It is tested with one- and two-loop scalar field theory, as well as one-loop and two-loop vacuum Yang-Mills diagrams, reproducing earlier results. It is then applied to two-loop two-point Yang-Mills diagrams in order to extract universal renormalization coefficients that can be compared to field theory. While developing numerous technical tools to compute the relevant contributions, we hit upon important conceptual questions: Do string diagrams reproduce Yang-Mills Feynman diagrams in a certain preferred gauge? Do they employ a certain preferred renormalization scheme? Are four gluon vertices related to three gluon vertices? Unfortunately, our investigations remained in...

  1. PyR@TE 2: A Python tool for computing RGEs at two-loop

    CERN Document Server

    Lyonnet, Florian

    2016-01-01

    Renormalization group equations are an essential tool for the description of theories accross different energy scales. Even though their expressions at two-loop for an arbitrary gauge field theory have been known for more than thirty years, deriving the full set of equations for a given model by hand is very challenging and prone to errors. To tackle this issue, we have introduced in [1] a Python tool called PyR@TE; Python Renormalization group equations @ Two-loop for Everyone. With PyR@TE, it is easy to implement a given Lagrangian and derive the complete set of two-loop RGEs for all the parameters of the theory. In this paper, we present the new version of this code, PyR@TE 2, which brings many new features and in particular it incorporates kinetic mixing when several $\\mathrm{U}(1)$ gauge groups are involved. In addition, the group theory part has been greatly improved as we introduced a new Python module dubbed PyLie that deals with all the group theoretical aspects required for the calculation of the RG...

  2. Regularization independent analysis of the origin of two loop contributions to N=1 Super Yang-Mills beta function

    Energy Technology Data Exchange (ETDEWEB)

    Fargnoli, H.G.; Sampaio, Marcos; Nemes, M.C. [Federal University of Minas Gerais, ICEx, Physics Department, P.O. Box 702, Belo Horizonte, MG (Brazil); Hiller, B. [Coimbra University, Faculty of Science and Technology, Physics Department, Center of Computational Physics, Coimbra (Portugal); Baeta Scarpelli, A.P. [Setor Tecnico-Cientifico, Departamento de Policia Federal, Lapa, Sao Paulo (Brazil)

    2011-05-15

    We present both an ultraviolet and an infrared regularization independent analysis in a symmetry preserving framework for the N=1 Super Yang-Mills beta function to two loop order. We show explicitly that off-shell infrared divergences as well as the overall two loop ultraviolet divergence cancel out, whilst the beta function receives contributions of infrared modes. (orig.)

  3. A reappraisal of two-loop contributions to the fermion electric dipole moments in R-parity violating supersymmetric models

    CERN Document Server

    Yamanaka, Nodoka; Kubota, Takahiro

    2012-01-01

    We reexamine the R-parity violating contribution to the fermion electric and chromo-electric dipole moments (EDM and cEDM) in the two-loop diagrams. It is found that the leading Barr-Zee type two-loop contribution is smaller than the result found in previous works, and that EDM experimental data provide looser limits on RPV couplings.

  4. The corrections from one loop and two-loop Barr-Zee type diagrams to muon MDM in BLMSSM

    CERN Document Server

    Zhao, Shu-Min; Zhang, Hai-Bin; Yan, Ben; Zhan, Xi-Jie

    2014-01-01

    In a supersymmetric extension of the standard model where baryon and lepton numbers are local gauge symmetries(BLMSSM) and the Yukawa couplings between Higgs doublets and exotic quarks are considered, we study the one loop diagrams and the two-loop Barr-Zee type diagrams with a closed Fermi(scalar) loop between the vector Boson and Higgs. Using the effective Lagrangian method, we deduce the Wilson coefficients of dimension 6 operators contributing to the anomalous magnetic moment of muon, which satisfies the electromagnetic gauge invariance. In the numerical analysis, we consider the experiment constraints from Higgs and neutrino data. In some parameter space, the new physics contribution is large and even reaches $24\\times10^{-10}$, which can remedy the deviation well.

  5. Two-loop Induced Majorana Neutrino Mass in a Radiatively Induced Quark and Lepton Mass Model

    CERN Document Server

    Nomura, Takaaki

    2016-01-01

    A two-loop induced radiative neutrino model is proposed as an extension of our previous work in which the first and second generation standard model fermion masses are generated at one-loop level in both quark and lepton sectors. Then we discuss current neutrino oscillation data, lepton flavor violations, muon anomalous magnetic moment, and a bosonic dark matter candidate, for both the normal and inverted neutrino mass hierarchy. Our numerical analysis shows that less hierarchical Yukawa coupling constants can fit the experimental data with TeV scale dark matter.

  6. The two-loop QCD correction to massive spin-2 resonance → q anti qg

    Energy Technology Data Exchange (ETDEWEB)

    Ahmed, Taushif; Rana, Narayan [The Institute of Mathematical Sciences, Chennai (India); Training School Complex, Homi Bhaba National Institute, Mumbai (India); Das, Goutam; Mathews, Prakash [Saha Institute of Nuclear Physics, Theory Division, Kolkata (India); Training School Complex, Homi Bhaba National Institute, Mumbai (India); Ravindran, V. [The Institute of Mathematical Sciences, Chennai (India)

    2016-12-15

    The two-loop QCD correction to massive spin-2 graviton decaying to q + anti q + g is presented considering a generic universal spin-2 coupling to the SM through the conserved energy-momentum tensor. Such a massive spin-2 particle can arise in extra-dimensional models. The ultraviolet and infrared structure of the QCD amplitudes are studied. In dimensional regularization, the infrared pole structure is in agreement with Catani's proposal, confirming the universal factorization property of QCD amplitudes, even with the spin-2 tensorial coupling. (orig.)

  7. Two-loop NF=1 QED Bhabha scattering differential cross section

    Science.gov (United States)

    Bonciani, R.; Ferroglia, A.; Mastrolia, P.; Remiddi, E.; van der Bij, J. J.

    2004-11-01

    We calculate the two-loop virtual, UV renormalized corrections at order α(N=1) in QED to the Bhabha scattering differential cross section, for arbitrary values of the squared c.m. energy s and momentum transfer t, and on-shell electrons and positrons of finite mass m. The calculation is carried out within the dimensional regularization scheme; the remaining IR divergences appear as polar singularities in (D-4). The result is presented in terms of 1- and 2-dimensional harmonic polylogarithms, of maximum weight 3.

  8. Two-loop NF=1 QED Bhabha scattering differential cross section

    Energy Technology Data Exchange (ETDEWEB)

    Bonciani, R. [Fakultaet fuer Mathematik und Physik, Albert-Ludwigs-Universitaet Freiburg, D-79104 Freiburg (Germany)]. E-mail: roberto.bonciani@physik.uni-freiburg.de; Ferroglia, A. [Fakultaet fuer Mathematik und Physik, Albert-Ludwigs-Universitaet Freiburg, D-79104 Freiburg (Germany)]. E-mail: andrea.ferroglia@physik.uni-freiburg.de; Mastrolia, P. [Department of Physics and Astronomy, UCLA, Los Angeles, CA 90095-1547 (United States)]. E-mail: mastrolia@physics.ucla.edu; Remiddi, E. [Physics Department, Theory Division, CERN, CH-1211 Geneva 23 (Switzerland); Dipartimento di Fisica dell' Universita di Bologna, and INFN, Sezione di Bologna, I-40126 Bologna (Italy)]. E-mail: ettore.remiddi@bo.infn.it; Bij, J.J. van der [Fakultaet fuer Mathematik und Physik, Albert-Ludwigs-Universitaet Freiburg, D-79104 Freiburg (Germany)]. E-mail: jochum@physik.uni-freiburg.de

    2004-11-22

    We calculate the two-loop virtual, UV renormalized corrections at order {alpha}4(NF=1) in QED to the Bhabha scattering differential cross section, for arbitrary values of the squared c.m. energy s and momentum transfer t, and on-shell electrons and positrons of finite mass m. The calculation is carried out within the dimensional regularization scheme; the remaining IR divergences appear as polar singularities in (D-4). The result is presented in terms of 1- and 2-dimensional harmonic polylogarithms, of maximum weight 3.

  9. Local integrands for two-loop all-plus Yang-Mills amplitudes

    CERN Document Server

    Badger, Simon; Peraro, Tiziano

    2016-01-01

    We express the planar five- and six-gluon two-loop Yang-Mills amplitudes with all positive helicities in compact analytic form using D-dimensional local integrands that are free of spurious singularities. The integrand is fixed from on-shell tree amplitudes in six dimensions using D-dimensional generalised unitarity cuts. The resulting expressions are shown to have manifest infrared behaviour at the integrand level. We also find simple representations of the rational terms obtained after integration in 4-2epsilon dimensions.

  10. R-parity violating two-loop level rainbowlike contribution to the fermion electric dipole moment

    CERN Document Server

    Yamanaka, Nodoka

    2012-01-01

    We analyze the two-loop level R-parity violating supersymmetric contribution to the electric and chromoelectric dipole moments of the fermion with neutrino and gaugino in the intermediate state. It is found that this contribution can be sufficiently enhanced with large tan {\\beta} and that it can have comparable size with the currently known R-parity violating Barr-Zee type process in the TeV scale supersymmetry breaking. We also give new limits on the R-parity violating couplings from the experimental data of the electric dipole moments of the neutron and the electron.

  11. Two-loop level rainbow-like supersymmetric contribution to the fermion EDM

    CERN Document Server

    Yamanaka, Nodoka

    2012-01-01

    We calculate the two-loop level electric and chromo-electric dipole moments of the fermion involving fermion-sfermion inner loop, gaugino, and higgsino in the minimal supersymmetric standard model, and analyze the chromo-electric dipole moment with the top-stop inner loop. It is found that this contribution is comparable with, and even dominates in some situation over the Barr-Zee type diagram generated from the CP-violation of the top squark sector in TeV scale supersymmetry breaking.

  12. Eikonal gluon bremsstrahlung at finite N_c beyond two loops

    CERN Document Server

    Delenda, Yazid

    2015-01-01

    We present a general formalism for computing the matrix-element squared for the emission of soft energy-ordered gluons beyond two loops in QCD perturbation theory at finite $N_c$. Our formalism is valid in the eikonal approximation. A Mathematica program has been developed for the automated calculation of all real/virtual eikonal squared amplitudes needed at a given loop order. For the purpose of illustration we show the explicit forms of the eikonal squared amplitudes up to the fifth-loop order. In the large-$N_c$ limit our results coincide with those previously reported in literature.

  13. Two-loop formfactors in theories with mass gap and Z-boson production

    Energy Technology Data Exchange (ETDEWEB)

    Kotikov, A. [Joint Inst. of Nuclear Research, Moscow (Russian Federation). Bogoliubov Lab. of Theoretical Physics]|[Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik; Kuehn, J.H. [Karlsruhe Univ. (T.H.) (Germany). Inst. fuer Theoretische Teilchenphysik; Veretin, O. [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik]|[Petrozavodsk Univ., Karelia (Russian Federation)

    2007-03-15

    The non-factorizable two-loop corrections to the formfactor both for a U(1) x U(1) and a SU(2) x U(1) gauge theory with massive and massless gauge bosons respectively is evaluated at arbitrary momentum transfer q{sup 2}. The asymptotic behaviour for q{sup 2}{yields}{infinity} is compared to a recent calculation of Sudakov logarithms. The result is an important ingredient for the calculation of radiative corrections to Z-boson production at hadron and lepton colliders. (orig.)

  14. Two-loop QED operator matrix elements with massive external fermion lines

    Energy Technology Data Exchange (ETDEWEB)

    Bluemlein, Johannes [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Freitas, Abilio de [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Universidad Simon Bolivar, Caracas (Venezuela). Dept. de Fisica; Neerven, Wilhelmus van [Leiden Univ. (Netherlands). Institut-Lorentz

    2011-07-15

    The two-loop massive operator matrix elements for the fermionic local twist-2 operators with external massive fermion lines in Quantum Electrodynamics (QED) are calculated up to the constant terms in the dimensional parameter {epsilon}=D-4. We investigate the hypothesis of F. A. Berends et al. (1988) that the 2-loop QED initial state corrections to e{sup +}e{sup -} annihilation into a virtual neutral gauge boson, except power corrections of O((m{sup 2}{sub f}/s){sup k}), k {>=} 1, can be represented in terms of these matrix elements and the massless 2-loop Wilson coefficients of the Drell-Yan process. (orig.)

  15. Precise numerical evaluation of the two loop sunrise graph Master Integrals in the equal mass case

    CERN Document Server

    Pozzorini, Stefano

    2006-01-01

    We present a double precision routine in Fortran for the precise and fast numerical evaluation of the two Master Integrals (MIs) of the equal mass two-loop sunrise graph for arbitrary momentum transfer in d=2 and d=4 dimensions. The routine implements the accelerated power series expansions obtained by solving the corresponding differential equations for the MIs at their singular points. With a maximum of 22 terms for the worst case expansion a relative precision of better than a part in 10^{15} is achieved for arbitrary real values of the momentum transfer.

  16. Planar two-loop master integrals for massive Bhabha scattering: N_f=1 and N_f=2

    CERN Document Server

    Actis, S; Gluza, J; Riemann, Tord; Actis, Stefano; Czakon, Michal; Gluza, Janusz; Riemann, Tord

    2006-01-01

    Recent developments in the computation of two-loop master integrals for massive Bhabha scattering are briefly reviewed. We apply a method based on expansions of exact Mellin-Barnes representations and evaluate all planar four-point master integrals in the approximation of small electron mass at fixed scattering angle for the one-flavor case. The same technique is employed to derive and evaluate also all two-loop masters generated by additional fermion flavors. The approximation is sufficient for the determination of QED two-loop corrections for Bhabha scattering in the kinematics planned to be used for the luminosity determination at the ILC.

  17. Two-loop snail diagrams: relating neutrino masses to dark matter

    CERN Document Server

    Farzan, Yasaman

    2014-01-01

    Various mechanisms have been developed to explain the origin of Majorana neutrino masses. One of them is radiative mass generation. Two-loop mass generation is of particular interest because the masses and couplings of new particles propagating in the loop can be in the range testable by other experiments and observations. In order for the radiative mass suppression to be reliable, it should be guaranteed that lower loop contributions are suppressed. Based on loop topology and the form of electroweak presentation of the particles propagating in the loop, one can determine whether a lower---and therefore dominant---loop contribution is possible. We present a model based on these general considerations which leads to neutrino masses via a two-loop diagram which we dub as "snail-diagram". The model has two natural candidates for dark matter one of them being a neutral Dirac fermion which can satisfy the conditions of the thermal freeze-out scenario by annihilation to lepton pairs. We comment on the possibility o...

  18. Two-loop snail diagrams: relating neutrino masses to dark matter

    Energy Technology Data Exchange (ETDEWEB)

    Farzan, Yasaman [Physics school, Institute for Research in Fundamental Sciences (IPM),P.O. Box 19395-5531, Tehran (Iran, Islamic Republic of)

    2015-05-06

    Various mechanisms have been developed to explain the origin of neutrino masses. One of them is radiative mass generation. Two-loop mass generation is of particular interest because the masses and couplings of new particles propagating in the loop can be in the range testable by other experiments and observations. In order for the radiative mass suppression to be reliable, it should be guaranteed that lower loop contributions are suppressed. Based on loop topology and the form of electroweak presentation of the particles propagating in the loop, one can determine whether a lower — and therefore dominant — loop contribution is possible. We present a model based on these general considerations which leads to neutrino masses via a two-loop diagram which we dub as “snail-diagram”. The model has two natural candidates for dark matter one of them being a neutral Dirac fermion which can satisfy the conditions of the thermal freeze-out scenario by annihilation to lepton pairs. We comment on the possibility of explaining the GeV gamma ray excess observed by Fermi-LAT from the region close to the Galaxy Center. We also discuss possible signals at the LHC and at experiments searching for lepton flavor violating rare decays.

  19. The two-loop helicity amplitudes for $q \\bar q' \\to V_1 V_2 \\to 4~\\mathrm{leptons}$

    CERN Document Server

    Gehrmann, Thomas; Tancredi, Lorenzo

    2015-01-01

    We compute the two-loop massless QCD corrections to the helicity amplitudes for the production of two massive vector bosons in quark-antiquark annihilation, allowing for an arbitrary virtuality of the vector bosons: $q \\bar q' \\to V_1V_2$. Combining with the leptonic decay currents, we obtain the full two-loop QCD description of the corresponding electroweak four-lepton production processes. The calculation is performed by projecting the two-loop diagrams onto an appropriate basis of Lorentz structures. All two-loop Feynman integrals are reduced to a basis of master integrals, which are then computed using the differential equations method and optimised for numerical performance. We provide a public C++ code which allows for fast and precise numerical evaluations of the amplitudes.

  20. QCD two-loop corrections for hadronic single top-quark production in the t-channel

    CERN Document Server

    Assadsolimani, M; Tausk, B; Uwer, P

    2014-01-01

    In this article we discuss the calculation of single top-quark production in the t-channel at two-loop order in QCD. In particular we present the decomposition of the amplitude according to its spin and colour structure and present complete results for the two-loop amplitudes in terms of master integrals. For the vertex corrections compact analytic expressions are given. The box contributions are implemented in a publicly available C program.

  1. Effective potential for relativistic scattering

    CERN Document Server

    Elbistan, Mahmut; Balog, Janos

    2016-01-01

    We consider quantum inverse scattering with singular potentials and calculate the Sine-Gordon model effective potential in the laboratory and centre-of-mass frames. The effective potentials are frame dependent but closely resemble the zero-momentum potential of the equivalent Ruijsenaars-Schneider model.

  2. Two-Loop QCD Corrections to Higgs $\\rightarrow b + \\bar{b} + g$ Amplitude

    CERN Document Server

    Ahmed, Taushif; Mathews, Prakash; Rana, Narayan; Ravindran, V

    2014-01-01

    Exclusive observables involving Higgs boson in association with jets are often well suited to study the Higgs boson properties. They are rates involving cuts on the final state jets or differential distributions of rapidity, transverse momentum of the observed Higgs boson. While they get dominant contributions from gluon initiated partonic subprocesses, it is important to include the subdominant ones coming from other channels. In this article, we study one such channel namely the Higgs production in association with a jet in bottom anti-bottom annihilation process. We compute relevant amplitude $H\\rightarrow b+\\overline b+g$ up to two loop level in QCD where Higgs couples to bottom quark through Yukawa coupling. We use projection operators to obtain the coefficients for each tensorial structure appearing in this process. We have demonstrated that the renormalized amplitudes do have the right infrared structure predicted by the QCD factorization in dimensional regularization. The finite parts of the one and t...

  3. Two-Loop Quantum Gravity Corrections to Cosmological Constant in Landau Gauge

    CERN Document Server

    Hamada, Ken-ji

    2015-01-01

    The anomalous dimensions of the Planck mass and the cosmological constant are calculated in a renormalizable quantum conformal gravity with a single dimensionless coupling, which is formulated using dimensional regularization on the basis of Hathrell's works for conformal anomalies. The dynamics of the traceless tensor field is handled by the Weyl action, while that of the conformal-factor field is described by the induced Wess-Zumino actions, including the Riegert action as the kinetic term. Loop calculations are carried out in Landau gauge in order to reduce the number of Feynman diagrams as well as to avoid some uncertainty. Especially, we calculate two-loop quantum gravity corrections to the cosmological constant. It suggests that there is a dynamical solution to the cosmological constant problem.

  4. Two-loop renormalization of vector, axial-vector and tensor fermion bilinears on the lattice

    CERN Document Server

    Skouroupathis, A

    2008-01-01

    We compute the two-loop renormalization functions, in the RI' scheme, of local bilinear quark operators $\\bar{\\psi}\\Gamma\\psi$, where $\\Gamma$ corresponds to the Vector, Axial-Vector and Tensor Dirac operators, in the lattice formulation of QCD. We consider both the flavor nonsinglet and singlet operators. We use the clover action for fermions and the Wilson action for gluons. Our results are given as a polynomial in $c_{SW}$, in terms of both the renormalized and bare coupling constant, in the renormalized Feynman gauge. Finally, we present our results in the MSbar scheme, for easier comparison with calculations in the continuum. The corresponding results, for fermions in an arbitrary representation, together with some special features of superficially divergent integrals, are included in the Appendices.

  5. Evidence for two-loop interaction from IRIS and SDO observations of penumbral brightenings

    Science.gov (United States)

    Alissandrakis, C. E.; Koukras, A.; Patsourakos, S.; Nindos, A.

    2017-07-01

    Aims: We investigate small scale energy release events which can provide clues on the heating mechanism of the solar corona. Methods: We analyzed spectral and imaging data from the Interface Region Imaging Spectrograph (IRIS), images from the Atmospheric Imaging Assembly (AIA) aboard the Solar Dynamics Observatoty (SDO), and magnetograms from the Helioseismic and Magnetic Imager (HMI) aboard SDO. Results: We report observations of small flaring loops in the penumbra of a large sunspot on July 19, 2013. Our main event consisted of a loop spanning 15'', from the umbral-penumbral boundary to an opposite polarity region outside the penumbra. It lasted approximately 10 min with a two minute impulsive peak and was observed in all AIA/SDO channels, while the IRIS slit was located near its penumbral footpoint. Mass motions with an apparent velocity of 100 km s-1 were detected beyond the brightening, starting in the rise phase of the impulsive peak; these were apparently associated with a higher-lying loop. We interpret these motions in terms of two-loop interaction. IRIS spectra in both the C ii and Si iv lines showed very extended wings, up to about 400 km s-1, first in the blue (upflows) and subsequently in the red wing. In addition to the strong lines, emission was detected in the weak lines of Cl i, O i and C i, as well as in the Mg ii triplet lines. Absorption features in the profiles of the C ii doublet, the Si iv doublet and the Mg ii h and k lines indicate the existence of material with a lower source function between the brightening and the observer. We attribute this absorption to the higher loop and this adds further credibility to the two-loop interaction hypothesis. Tilts were detected in the absorption spectra, as well as in the spectra of Cl i, O i, and C i lines, possibly indicating rotational motions from the untwisting of magnetic flux tubes. Conclusions: We conclude that the absorption features in the C ii, Si iv and Mg ii profiles originate in a higher

  6. Two-Loop QCD Correction to massive spin-2 resonance $\\rightarrow$ 3 gluons

    CERN Document Server

    Ahmed, Taushif; Mathews, Prakash; Rana, Narayan; Ravindran, V

    2014-01-01

    We present the ${\\cal O}(\\alpha_s^3)$ virtual QCD corrections to the process $h \\rightarrow g+g+g$ due to interference of born and two-loop amplitudes, where $h$ is a massive spin-2 particle and $g$ is the gluon. We assume that the SM fields couple to $h$ through the SM energy momentum tensor. Our result constitutes one of the ingredients to full NNLO QCD contribution to production of a massive spin-2 particle along with a jet in the scattering process at the LHC. In particular, this massive spin-2 could be a KK mode of a ADD graviton in large extra dimensional model or a RS KK mode in warped extra dimensional model or a generic massive spin-2. In addition, it provides an opportunity to study the ultraviolet and infrared structures of QCD amplitudes involving tensorial coupling resulting from energy momentum operator. Using dimensional regularization, we find that infrared poles of this amplitude are in agreement with the proposal by Catani confirming the factorization property of QCD amplitudes with tensoria...

  7. The Two-Loop Six-Gluon MHV Amplitude in Maximally Supersymmetric Yang-Mills Theory

    CERN Document Server

    Bern, Z; Kosower, D A; Roiban, R; Spradlin, M; Vergu, C; Volovich, A

    2008-01-01

    We give a representation of the parity-even part of the planar two-loop six-gluon MHV amplitude of N=4 super-Yang-Mills theory, in terms of loop-momentum integrals with simple dual conformal properties. We evaluate the integrals numerically in order to test directly the ABDK/BDS all-loop ansatz for planar MHV amplitudes. We find that the ansatz requires an additive remainder function, in accord with previous indications from strong-coupling and Regge limits. The planar six-gluon amplitude can also be compared with the hexagonal Wilson loop computed by Drummond, Henn, Korchemsky and Sokatchev in arXiv:0803.1466 [hep-th]. After accounting for differing singularities and other constants independent of the kinematics, we find that the Wilson loop and MHV-amplitude remainders are identical, to within our numerical precision. This result provides non-trivial confirmation of a proposed n-point equivalence between Wilson loops and planar MHV amplitudes, and suggests that an additional mechanism besides dual conformal...

  8. Two-loop stability of a complex singlet extended standard model

    Science.gov (United States)

    Costa, Raul; Morais, António P.; Sampaio, Marco O. P.; Santos, Rui

    2015-07-01

    Motivated by the dark matter and the baryon asymmetry problems, we analyze a complex singlet extension of the Standard Model with a Z2 symmetry (which provides a dark matter candidate). After a detailed two-loop calculation of the renormalization group equations for the new scalar sector, we study the radiative stability of the model up to a high energy scale (with the constraint that the 126 GeV Higgs boson found at the LHC is in the spectrum) and find it requires the existence of a new scalar state mixing with the Higgs with a mass larger than 140 GeV. This bound is not very sensitive to the cutoff scale as long as the latter is larger than 1010 GeV . We then include all experimental and observational constraints/measurements from collider data, from dark matter direct detection experiments, and from the Planck satellite and in addition force stability at least up to the grand unified theory scale, to find that the lower bound is raised to about 170 GeV, while the dark matter particle must be heavier than about 50 GeV.

  9. Higgs boson mass in the Standard Model at two-loop order and beyond

    Energy Technology Data Exchange (ETDEWEB)

    Martin, Stephen P. [Northern Illinois U.; Robertson, David G. [Otterbein Coll.

    2014-10-23

    We calculate the mass of the Higgs boson in the standard model in terms of the underlying Lagrangian parameters at complete 2-loop order with leading 3-loop corrections. A computer program implementing the results is provided. The program also computes and minimizes the standard model effective potential in Landau gauge at 2-loop order with leading 3-loop corrections.

  10. Two-loop electroweak corrections to the A{sup 0}{gamma}{gamma} and A{sup 0}gg couplings of the CP-odd Higgs boson

    Energy Technology Data Exchange (ETDEWEB)

    Brod, J. [Karlsruhe Univ. (T.H.) (Germany). Inst. fuer Theoretische Teilchenphysik; Fugel, F. [Paul Scherrer Inst. (PSI), Villigen (Switzerland); Kniehl, B.A. [Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik

    2008-06-15

    Using the asymptotic-expansion technique, we compute the dominant two-loop electroweak corrections, of O(G{sub F}m{sup 2}{sub t}), to production and decay via a pair of photons or gluons of the CP-odd Higgs boson A{sup 0} in a two-Higgs-doublet model with low- to intermediate values of the Higgs-boson masses and ratio tan {beta}=v{sub 2}/v{sub 1} of the vacuum expectation values. We also study the influence of a sequential heavyfermion generation. The appearance of three {gamma}{sub 5} matrices in closed fermion loops requires special care in the dimensional regularisation of ultraviolet divergences. The finite renormalisation constant for the pseudoscalar current effectively restoring the anticommutativity of the {gamma}{sub 5} matrix, familiar from perturbative quantum chromodynamics, is found not to receive a correction in this order. We also revisit the dominant two-loop electroweak correction to the H{yields}{gamma}{gamma} decay width in the standard model with a fourth fermion generation. (orig.)

  11. Two-loop two-point functions with masses asymptotic expansions and Taylor series, in any dimension

    CERN Document Server

    Broadhurst, D J; Tarasov, O V

    1993-01-01

    In all mass cases needed for quark and gluon self-energies, the two-loop master diagram is expanded at large and small $q^2$, in $d$ dimensions, using identities derived from integration by parts. Expansions are given, in terms of hypergeometric series, for all gluon diagrams and for all but one of the quark diagrams; expansions of the latter are obtained from differential equations. Pad\\'{e} approximants to truncations of the expansions are shown to be of great utility. As an application, we obtain the two-loop photon self-energy, for all $d$, and achieve highly accelerated convergence of its expansions in powers of $q^2/m^2$ or $m^2/q^2$, for $d=4$.

  12. Computation of $H\\to gg$ in FDH and DRED: renormalization, operator mixing, and explicit two-loop results

    CERN Document Server

    Broggio, A; Signer, A; Stöckinger, D; Visconti, A

    2015-01-01

    The $H\\to gg$ amplitude relevant for Higgs production via gluon fusion is computed in the four-dimensional helicity scheme (FDH) and in dimensional reduction (DRED) at the two-loop level. The required renormalization is developed and described in detail, including the treatment of evanescent $\\epsilon$-scalar contributions. In FDH and DRED there are additional dimension-5 operators generating the $H g g$ vertices, where $g$ can either be a gluon or an $\\epsilon$-scalar. An appropriate operator basis is given and the operator mixing through renormalization is described. The results of the present paper provide building blocks for further computations, and they allow to complete the study of the infrared divergence structure of two-loop amplitudes in FDH and DRED.

  13. Two-loop electroweak corrections to Higgs-gluon couplings to higher orders in the dimensional regularization parameter

    CERN Document Server

    Bonetti, Marco; Tancredi, Lorenzo

    2016-01-01

    We compute the two-loop electroweak correction to the production of the Higgs boson in gluon fusion to higher orders in the dimensional-regularization parameter $\\epsilon = (d-4)/2$. We employ the method of differential equations to compute the relevant integrals and express them in terms of Goncharov polylogarithms. Our result provides one of the necessary inputs for the computation of mixed three-loop QCD-electroweak corrections to $gg \\to H$.

  14. 30 years, some 700 integrals, and 1 dessert, or: Electroweak two-loop corrections to the Zbb vertex

    CERN Document Server

    Dubovyk, I; Gluza, J; Riemann, T; Usovitsch, J

    2016-01-01

    The one-loop corrections to the weak mixing angle $\\sin^2\\theta_{eff}^b$ derived from the $Z{\\bar b}b$ vertex, are known since 1985. It took another 30 years to calculate the complete electroweak two-loop corrections to $\\sin^2\\theta_{eff}^b$. The main obstacle was the calculation of the O(700) bosonic two-loop vertex integrals with up to three mass scales, at $s=M_Z^2$. We did not perform the usual integral reduction and master evaluation, but chose a completely numerical approach, using two different calculational chains. One method relies on publicly available sector decomposition implementations. Further, we derived Mellin-Barnes (MB) representations, exploring the publicly available MB suite. We had to supplement the MB suite by two new packages: AMBRE~3, a Mathematica program, for the efficient treatment of non-planar integrals and MBnumerics for advanced numerics in the Minkowskian space-time. Our preliminary result for LL2016, the "dessert", for the electroweak bosonic two-loop contributions to $\\sin^...

  15. Renormalization scheme dependence of the two-loop QCD corrections to the neutral Higgs-boson masses in the MSSM

    Energy Technology Data Exchange (ETDEWEB)

    Borowka, S. [University of Zurich, Institute for Physics, Zurich (Switzerland); Hahn, T.; Heinrich, G.; Hollik, W. [Max-Planck-Institut fuer Physik (Werner-Heisenberg-Institut), Muenchen (Germany); Heinemeyer, S. [Instituto de Fisica de Cantabria (CSIC-UC), Santander (Spain)

    2015-09-15

    Reaching a theoretical accuracy in the prediction of the lightest MSSM Higgs-boson mass, M{sub h}, at the level of the current experimental precision requires the inclusion of momentum-dependent contributions at the two-loop level. Recently two groups presented the two-loop QCD momentum-dependent corrections to M{sub h} (Borowka et al., Eur Phys J C 74(8):2994, 2014; Degrassi et al., Eur Phys J C 75(2):61, 2015), using a hybrid on-shell-DR scheme, with apparently different results. We show that the differences can be traced back to a different renormalization of the top-quark mass, and that the claim in Ref. Degrassi et al. (Eur Phys J C 75(2):61, 2015) of an inconsistency in Ref. Borowka et al. (Eur Phys J C 74(8):2994, 2014) is incorrect. We furthermore compare consistently the results for M{sub h} obtained with the top-quark mass renormalized on-shell and DR. The latter calculation has been added to the FeynHiggs package and can be used to estimate missing higher-order corrections beyond the two-loop level. (orig.)

  16. Potential neuroprotective effects of cinnamon

    Directory of Open Access Journals (Sweden)

    Rebecca Crews Stavinoha

    2015-07-01

    Full Text Available Summary. The pathogenesis of neurodegenerative diseases involves complex interactions between multiple mechanisms, including but not limited to oxidative stress, inflammation, and proteotoxicity, which have yet to be ameliorated by pharmaceutical drugs with single targets. Natural products have been recognized for their health promoting effects for thousands of years. Plants produce a vast collection of secondary products, such as alkaloids, phenolic compounds, and terpenes that have shown health benefits in a variety of conditions including cancer, cardiovascular disease, and neurodegenerative diseases. In the search for more effective and safe treatment options for neurodegenerative diseases, several dietary sources of phytochemicals have been investigated. Historical usage in traditional medicine, along with modern research has identified several key products with potential benefits in neurodegenerative diseases. Among the dietary sources, cinnamon shows particular merit as a therapeutic potential for neurodegenerative diseases. Accumulating evidence suggesting neuroprotective effects via modulation of various risk factors relevant to neurodegeneration has been reviewed here. Industrial relevance. Cinnamon has been cherished for its health-promoting effects for thousands of years. Today, while modern medicine provides critical pharmaceutical agents that have assisted in ameliorating many diseases and extended the average lifespan significantly in the past century, these agents are associated with many side effects and expenses. As such, the search for efficient therapies with limited side effects is a significant target of research. Cinnamon, as a rich source of phytochemicals and long history in traditional medicine, has been a popular spice in recent decades for investigations elucidating its health-promoting effects. This review evaluates the therapeutic potential of cinnamon in ameliorating the risk factors responsible for the development

  17. Evaluation of two loop-mediated isothermal amplification methods for the detection of Salmonella Enteritidis and Listeria monocytogenes in artificially contaminated ready-to-eat fresh products

    Directory of Open Access Journals (Sweden)

    Angeliki Birmpa

    2015-08-01

    Full Text Available In the present study, the effectiveness of two loop-mediated isothermal amplification (LAMP assays was evaluated. Samples of romaine lettuce, strawberries, cherry tomatoes, green onions and sour berries were inoculated with known dilutions (100-108 CFU/g of produce of S. Enteritidis and L. monocytogenes. With LAMP assay, pathogens can be detected in less than 60 min. The limits of detection of S. Enteritidis and L. monocytogenes depended on the food sample tested and on the presence of enrichment step. After enrichment steps, all food samples were found positive even at low initial pathogen levels. The developed LAMP, assays, are expected to become a valuable, robust, innovative, powerful, cheap and fast monitoring tool, which can be extensively used for routine analysis, and screening of contaminated foods by the food industry and the Public Food Health Authorities.

  18. The effective crystal field potential

    CERN Document Server

    Mulak, J

    2000-01-01

    As it results from the very nature of things, the spherical symmetry of the surrounding of a site in a crystal lattice or an atom in a molecule can never occur. Therefore, the eigenfunctions and eigenvalues of any bound ion or atom have to differ from those of spherically symmetric respective free ions. In this way, the most simplified concept of the crystal field effect or ligand field effect in the case of individual molecules can be introduced. The conventional notion of the crystal field potential is narrowed to its non-spherical part only through ignoring the dominating spherical part which produces only a uniform energy shift of gravity centres of the free ion terms. It is well understood that the non-spherical part of the effective potential "seen" by open-shell electrons localized on a metal ion plays an essential role in most observed properties. Light adsorption, electron paramagnetic resonance, inelastic neutron scattering and basic characteristics derived from magnetic and thermal measurements, ar...

  19. Analytic Result for the Two-loop Six-point NMHV Amplitude in N = 4 Super Yang-Mills Theory

    Energy Technology Data Exchange (ETDEWEB)

    Dixon, Lance J.; /SLAC; Drummond, James M.; /CERN /Annecy, LAPTH; Henn, Johannes M.; /Humboldt U., Berlin /Princeton, Inst. Advanced Study

    2012-02-15

    We provide a simple analytic formula for the two-loop six-point ratio function of planar N = 4 super Yang-Mills theory. This result extends the analytic knowledge of multi-loop six-point amplitudes beyond those with maximal helicity violation. We make a natural ansatz for the symbols of the relevant functions appearing in the two-loop amplitude, and impose various consistency conditions, including symmetry, the absence of spurious poles, the correct collinear behavior, and agreement with the operator product expansion for light-like (super) Wilson loops. This information reduces the ansatz to a small number of relatively simple functions. In order to fix these parameters uniquely, we utilize an explicit representation of the amplitude in terms of loop integrals that can be evaluated analytically in various kinematic limits. The final compact analytic result is expressed in terms of classical polylogarithms, whose arguments are rational functions of the dual conformal cross-ratios, plus precisely two functions that are not of this type. One of the functions, the loop integral {Omega}{sup (2)}, also plays a key role in a new representation of the remainder function R{sub 6}{sup (2)} in the maximally helicity violating sector. Another interesting feature at two loops is the appearance of a new (parity odd) x (parity odd) sector of the amplitude, which is absent at one loop, and which is uniquely determined in a natural way in terms of the more familiar (parity even) x (parity even) part. The second non-polylogarithmic function, the loop integral {tilde {Omega}}{sup (2)}, characterizes this sector. Both {Omega}{sup (2)} and {tilde {Omega}}{sup (2)} can be expressed as one-dimensional integrals over classical polylogarithms with rational arguments.

  20. Analytic Result for the Two-loop Six-point NMHV Amplitude in N = 4 Super Yang-Mills Theory

    Energy Technology Data Exchange (ETDEWEB)

    Dixon, Lance J.; /SLAC; Drummond, James M.; /CERN /Annecy, LAPTH; Henn, Johannes M.; /Humboldt U., Berlin /Princeton, Inst. Advanced Study

    2012-02-15

    We provide a simple analytic formula for the two-loop six-point ratio function of planar N = 4 super Yang-Mills theory. This result extends the analytic knowledge of multi-loop six-point amplitudes beyond those with maximal helicity violation. We make a natural ansatz for the symbols of the relevant functions appearing in the two-loop amplitude, and impose various consistency conditions, including symmetry, the absence of spurious poles, the correct collinear behavior, and agreement with the operator product expansion for light-like (super) Wilson loops. This information reduces the ansatz to a small number of relatively simple functions. In order to fix these parameters uniquely, we utilize an explicit representation of the amplitude in terms of loop integrals that can be evaluated analytically in various kinematic limits. The final compact analytic result is expressed in terms of classical polylogarithms, whose arguments are rational functions of the dual conformal cross-ratios, plus precisely two functions that are not of this type. One of the functions, the loop integral {Omega}{sup (2)}, also plays a key role in a new representation of the remainder function R{sub 6}{sup (2)} in the maximally helicity violating sector. Another interesting feature at two loops is the appearance of a new (parity odd) x (parity odd) sector of the amplitude, which is absent at one loop, and which is uniquely determined in a natural way in terms of the more familiar (parity even) x (parity even) part. The second non-polylogarithmic function, the loop integral {tilde {Omega}}{sup (2)}, characterizes this sector. Both {Omega}{sup (2)} and {tilde {Omega}}{sup (2)} can be expressed as one-dimensional integrals over classical polylogarithms with rational arguments.

  1. Differential equations and dispersion relations for Feynman amplitudes. The two-loop massive sunrise and the kite integral

    CERN Document Server

    Remiddi, Ettore

    2016-01-01

    It is shown that the study of the imaginary part and of the corresponding dispersion relations of Feynman graph amplitudes within the differential equations method can provide a powerful tool for the solution of the equations, especially in the massive case. The main features of the approach are illustrated by discussing the simple cases of the 1-loop self-mass and of a particular vertex amplitude, and then used for the evaluation of the two-loop massive sunrise and the QED kite graph (the problem studied by Sabry in 1962), up to first order in the (d-4) expansion.

  2. Differential equations and dispersion relations for Feynman amplitudes. The two-loop massive sunrise and the kite integral

    Science.gov (United States)

    Remiddi, Ettore; Tancredi, Lorenzo

    2016-06-01

    It is shown that the study of the imaginary part and of the corresponding dispersion relations of Feynman graph amplitudes within the differential equations method can provide a powerful tool for the solution of the equations, especially in the massive case. The main features of the approach are illustrated by discussing the simple cases of the 1-loop self-mass and of a particular vertex amplitude, and then used for the evaluation of the two-loop massive sunrise and the QED kite graph (the problem studied by Sabry in 1962), up to first order in the (d - 4) expansion.

  3. The two-loop helicity amplitudes for $gg \\to V_1 V_2 \\to 4~\\mathrm{leptons}$

    CERN Document Server

    von Manteuffel, Andreas

    2015-01-01

    We compute the two-loop massless QCD corrections to the helicity amplitudes for the production of two electroweak gauge bosons in the gluon fusion channel, $gg \\to V_1 V_2$, keeping the virtuality of the vector bosons $V_1$ and $V_2$ arbitrary and taking their decays into leptons into account. The amplitudes are expressed in terms of master integrals, whose representation has been optimised for fast and reliable numerical evaluation. We provide analytical results and a public C++ code for their numerical evaluation on HepForge at http://vvamp.hepforge.org .

  4. RegPT: Direct and fast calculation of regularized cosmological power spectrum at two-loop order

    CERN Document Server

    Taruya, Atsushi; Nishimichi, Takahiro; Codis, Sandrine

    2012-01-01

    We present a specific prescription for the calculation of cosmological power spectra, exploited here at two-loop order in perturbation theory (PT), based on the multi-point propagator expansion. In this approach power spectra are constructed from the regularized expressions of the propagators that reproduce both the resummed behavior in the high-k limit and the standard PT results at low-k. With the help of N-body simulations, we show that such a construction gives robust and accurate predictions for both the density power spectrum and the correlation function at percent-level in the weakly non-linear regime. We then present an algorithm that allows accelerated evaluations of all the required diagrams by reducing the computational tasks to one-dimensional integrals. This is achieved by means of pre-computed kernel sets defined for appropriately chosen fiducial models. The computational time for two-loop results is then reduced from a few minutes, with the direct method, to a few seconds with the fast one. The...

  5. Status of effective potential calculations

    CERN Document Server

    Quiros, M.

    1995-01-01

    We review various effective potential methods which have been useful to compute the Higgs mass spectrum and couplings of the minimal supersymmetric standard model. We compare results where all-loop next-to-leading-log corrections are resummed by the renormalization group, with those where just the leading-log corrections are kept. Pole masses are obtained from running masses by addition of convenient self-energy diagrams. Approximate analytical expressions are worked out, providing an excellent approximation to the numerical results which include all next-to-leading-log terms. An appropriate treatment of squark decoupling allows to consider large values of the stop and/or sbottom mixing parameters and thus fix a reliable upper bound on the mass of the lightest CP-even Higgs boson mass.

  6. Two-loop amplitudes and master integrals for the production of a Higgs boson via a massive quark and a scalar-quark loop

    CERN Document Server

    Anastasiou, C; Bucherer, S; Daleo, A; Kunszt, Zoltán; Anastasiou, Charalampos; Beerli, Stefan; Bucherer, Stefan; Daleo, Alejandro; Kunszt, Zoltan

    2007-01-01

    We compute all two-loop master integrals which are required for the evaluation of next-to-leading order QCD corrections in Higgs boson production via gluon fusion. Many two-loop amplitudes for 2 -> 1 processes in the Standard Model and beyond can be expressed in terms of these integrals using automated reduction techniques. These integrals also form a subset of the master integrals for more complicated 2 -> 2 amplitudes with massive propagators in the loops. As a first application, we evaluate the two-loop amplitude for Higgs boson production in gluon fusion via a massive quark. Our result is the first independent check of the calculation of Spira, Djouadi, Graudenz and Zerwas. We also present for the first time the two-loop amplitude for gg -> h via a massive squark.

  7. Numerical integration of massive two-loop Mellin-Barnes integrals in Minkowskian regions

    Energy Technology Data Exchange (ETDEWEB)

    Dubovyk, Ievgen [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Hamburg Univ. (Germany). 2. Inst. fuer Theoretische Physik; Gluza, Janusz [Uniwersytet Slaski, Katowice (Poland). Inst. Fizyki; Riemann, Tord [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Uniwersytet Slaski, Katowice (Poland). Inst. Fizyki; Usovitsch, Johann [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany)

    2016-07-15

    Mellin-Barnes (MB) techniques applied to integrals emerging in particle physics perturbative calculations are summarized. New versions of AMBRE packages which construct planar and nonplanar MB representations are shortly discussed. The numerical package MBnumerics.m is presented for the first time which is able to calculate with a high precision multidimensional MB integrals in Minkowskian regions. Examples are given for massive vertex integrals which include threshold effects and several scale parameters.

  8. Two-loop planar master integrals for Higgs$\\to 3$ partons with full heavy-quark mass dependence

    CERN Document Server

    Bonciani, Roberto; Frellesvig, Hjalte; Henn, Johannes M; Moriello, Francesco; Smirnov, Vladimir A

    2016-01-01

    We present the analytic computation of all the planar master integrals which contribute to the two-loop scattering amplitudes for Higgs$\\to 3$ partons, with full heavy-quark mass dependence. These are relevant for the NNLO corrections to fully inclusive Higgs production and to the NLO corrections to Higgs production in association with a jet, in the full theory. The computation is performed using the differential equations method. Whenever possible, a basis of master integrals that are pure functions of uniform weight is used. The result is expressed in terms of one-fold integrals of polylogarithms and elementary functions up to transcendental weight four. Two integral sectors are expressed in terms of elliptic functions. We show that by introducing a one-dimensional parametrization of the integrals the relevant second order differential equation can be readily solved, and the solution can be expressed to all orders of the dimensional regularization parameter in terms of iterated integrals over elliptic kerne...

  9. Extending two Higgs doublet models for two-loop neutrino mass generation and one-loop neutrinoless double beta decay

    CERN Document Server

    Liu, Zhen

    2016-01-01

    We extend some two Higgs doublet models, where the Yukawa couplings for the charged fermion mass generation only involve one Higgs doublet, by two singlet scalars respectively carrying a singly electric charge and a doubly electric charge. The doublet and singlet scalars together can mediate a two-loop diagram to generate a tiny Majorana mass matrix of the standard model neutrinos. Remarkably, the structure of the neutrino mass matrix is fully determined by the symmetric Yukawa couplings of the doubly charged scalar to the right-handed leptons. Meanwhile, a one-loop induced neutrinoless double beta decay can arrive at a testable level even if the electron neutrino has an extremely small Majorana mass. We also study other experimental constraints and implications including some rare processes and Higgs phenomenology.

  10. Extending two Higgs doublet models for two-loop neutrino mass generation and one-loop neutrinoless double beta decay

    Directory of Open Access Journals (Sweden)

    Zhen Liu

    2017-02-01

    Full Text Available We extend some two Higgs doublet models, where the Yukawa couplings for the charged fermion mass generation only involve one Higgs doublet, by two singlet scalars respectively carrying a singly electric charge and a doubly electric charge. The doublet and singlet scalars together can mediate a two-loop diagram to generate a tiny Majorana mass matrix of the standard model neutrinos. Remarkably, the structure of the neutrino mass matrix is fully determined by the symmetric Yukawa couplings of the doubly charged scalar to the right-handed leptons. Meanwhile, a one-loop induced neutrinoless double beta decay can arrive at a testable level even if the electron neutrino has an extremely small Majorana mass. We also study other experimental constraints and implications including some rare processes and Higgs phenomenology.

  11. Extending two Higgs doublet models for two-loop neutrino mass generation and one-loop neutrinoless double beta decay

    Science.gov (United States)

    Liu, Zhen; Gu, Pei-Hong

    2017-02-01

    We extend some two Higgs doublet models, where the Yukawa couplings for the charged fermion mass generation only involve one Higgs doublet, by two singlet scalars respectively carrying a singly electric charge and a doubly electric charge. The doublet and singlet scalars together can mediate a two-loop diagram to generate a tiny Majorana mass matrix of the standard model neutrinos. Remarkably, the structure of the neutrino mass matrix is fully determined by the symmetric Yukawa couplings of the doubly charged scalar to the right-handed leptons. Meanwhile, a one-loop induced neutrinoless double beta decay can arrive at a testable level even if the electron neutrino has an extremely small Majorana mass. We also study other experimental constraints and implications including some rare processes and Higgs phenomenology.

  12. Neural-network-based two-loop control of robotic manipulators including actuator dynamics in task space

    Institute of Scientific and Technical Information of China (English)

    Liangyong WANG; Tianyou CHAI; Zheng FANG

    2009-01-01

    A neural-network-based motion controller in task space is presented in this paper. The proposed controller is addressed as a two-loop cascade control scheme. The outer loop is given by kinematic control in the task space. It provides a joint velocity reference signal to the inner one. The inner loop implements a velocity servo loop at the robot joint level. A radial basis function network (RBFN) is integrated with proportional-integral (PI) control to construct a velocity tracking control scheme for the inner loop. Finally, a prototype technology based control system is designed for a robotic manipulator. The proposed control scheme is applied to the robotic manipulator. Experimental results confirm the validity of the proposed control scheme by comparing it with other control strategies.

  13. Two--Loop Anomalous Dimension Matrix for $\\Delta S=1$ Weak Non-Leptonic Decays; 2, ${\\cal O}(\\alpha_e \\alpha_s)$

    CERN Document Server

    Buras, Andrzej J; Lautenbacher, M E; Buras, Andrzej J.; Jamin, Matthias; Lautenbacher, Markus E.

    1993-01-01

    We calculate the $10\\times 10$ two--loop anomalous dimension matrix to order $\\ord(\\alpha_e \\alpha_s)$ in the dimensional regularization scheme with anticommuting $\\gamma_5$ (NDR) which is necessary for the extension of the $\\Delta S=1$ weak Hamiltonian involving electroweak penguins beyond the leading logarithmic approximation. We demonstrate, how a direct calculation of penguin diagrams involving $\\gamma_5$ in closed fermion loops can be avoided thus allowing a consistent calculation of two--loop anomalous dimensions in the simplest renormalization scheme with anticommuting $\\gamma_5$ in $D$ dimensions. We give the necessary one--loop finite terms which allow to obtain the corresponding two--loop anomalous dimension matrix in the HV scheme with non--anticommuting $\\gamma_5$.

  14. The calculation of the two-loop spin splitting functions P{sub ij}{sup (1)}(x)

    Energy Technology Data Exchange (ETDEWEB)

    Mertig, R. [Nationaal Inst. voor Kernfysica en Hoge-Energiefysica (NIKHEF), Amsterdam (Netherlands). Sectie H; Neerven, W.L. van [Rijksuniversiteit Leiden (Netherlands). Inst. Lorentz voor Theoretische Natuurkunde

    1995-06-01

    We present the calculation of the two-loop spin splitting functions P{sub ij}{sup (1)}(x) (i, j=q, g) contributing to the next-to-leading order corrected spin structure function g{sub 1}(x, Q{sup 2}). These splitting functions, which are presented in the anti M anti S scheme, are derived from the order {alpha}{sub s}{sup 2} contribution to the anomalous dimensions {gamma}{sup m}{sub ij} (i, j=q, g). The latter correspond to the local operators which appear in the operator product expansion of two electromagnetic currents. Some of the properties of the anomalous dimensions will be discussed. In particular we find that in order {alpha}{sub s}{sup 2} the supersymmetric relation {gamma}{sup m}{sub qq}+{gamma}{sup m}{sub qg}-{gamma}{sup m}{sub qg}-{gamma}{sup m}{sub gg}=0 is violated. (orig.).

  15. Analytic calculation of two-loop QCD corrections to b → sl+l- in the high q2 region

    Science.gov (United States)

    Greub, C.; Pilipp, V.; Schüpbach, C.

    2008-12-01

    We present our results for the NNLL virtual corrections to the matrix elements of the operators O1 and O2 for the inclusive process b → sl+l- in the kinematical region q2 > 4mc2, where q2 is the invariant mass squared of the lepton-pair. This is the first analytic two-loop calculation of these matrix elements in the high q2 region. We give the matrix elements as an expansion in mc/mb and keep the full analytic dependence on q2. Making extensive use of differential equation techniques, we fully automatize the expanding of the Feynman integrals in mc/mb. In coincidence with an earlier work where the master integrals were obtained numerically [1], we find that in the high q2 region the αs corrections to the matrix elements langlesl+l-|O1,2|brangle calculated in the present paper lead to a decrease of the perturbative part of the q2-spectrum by 10%-15% relative to the NNLL result in which these contributions are put to zero and reduce the renormalization scale uncertainty to ~ 2%.

  16. Two-loop master integrals for the mixed EW-QCD virtual corrections to Drell-Yan scattering

    Science.gov (United States)

    Bonciani, Roberto; Di Vita, Stefano; Mastrolia, Pierpaolo; Schubert, Ulrich

    2016-09-01

    We present the calculation of the master integrals needed for the two-loop QCD × EW corrections to q+overline{q}to {l}-+{l}+ and q+overline{q}^'to {l}-+overline{ν} , for massless external particles. We treat the W and Z bosons as degenerate in mass. We identify three types of diagrams, according to the presence of massive internal lines: the no-mass type, the one-mass type, and the two-mass type, where all massive propagators, when occurring, contain the same mass value. We find a basis of 49 master integrals and evaluate them with the method of the differential equations. The Magnus exponential is employed to choose a set of master integrals that obeys a canonical system of differential equations. Boundary conditions are found either by matching the solutions onto simpler integrals in special kinematic configurations, or by requiring the regularity of the solution at pseudothresholds. The canonical master integrals are finally given as Taylor series around d = 4 space-time dimensions, up to order four, with coefficients given in terms of iterated integrals, respectively up to weight four.

  17. Two-loop master integrals for the mixed EW-QCD virtual corrections to Drell-Yan scattering

    Energy Technology Data Exchange (ETDEWEB)

    Bonciani, Roberto [' ' La Sapienza' ' Univ., Rome (Italy). Dipt. di Fisica; INFN Sezione Roma (Italy); Di Vita, Stefano [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Mastrolia, Pierpaolo [Max-Planck-Institut fuer Physik, Muenchen (Germany); Padova Univ. (Italy). Dipt. di Fisica e Astronomia; INFN Sezione di Padova (Italy); Schubert, Ulrich [Max-Planck-Institut fuer Physik, Muenchen (Germany)

    2016-04-15

    We present the calculation of the master integrals needed for the two-loop QCD x EW corrections to q+ anti q → l{sup -}+l{sup +} and q+ anti q{sup '} → l{sup -}+ anti ν, for massless external particles. We treat W and Z bosons as degenerate in mass. We identify three types of diagrams, according to the presence of massive internal lines: the no-mass type, the one-mass type, and the two-mass type, where all massive propagators, when occurring, contain the same mass value. We find a basis of 49 master integrals and evaluate them with the method of the differential equations. The Magnus exponential is employed to choose a set of master integrals that obeys a canonical system of differential equations. Boundary conditions are found either by matching the solutions onto simpler integrals in special kinematic configurations, or by requiring the regularity of the solution at pseudo-thresholds. The canonical master integrals are finally given as Taylor series around d=4 space-time dimensions, up to order four, with coefficients given in terms of iterated integrals, respectively up to weight four.

  18. Two-loop fermion self-energy in reduced quantum electrodynamics and application to the ultra-relativistic limit of graphene

    CERN Document Server

    Kotikov, A V

    2013-01-01

    We compute the two-loop fermion self-energy in massless reduced quantum electrodynamics for an arbitrary gauge using the method of integration by parts. Focusing on the limit where the photon field is four-dimensional, our formula involves only recursively one-loop integrals and can therefore be evaluated exactly. From this formula, we deduce the anomalous scaling dimension of the fermion field as well as the renormalized fermion propagator up to two loops. The results are then applied to the ultra-relativistic limit of graphene and compared with similar results obtained for four-dimensional and three-dimensional quantum electrodynamics.

  19. Symmetry-improved 2PI approach to the Goldstone-boson IR problem of the SM effective potential

    Science.gov (United States)

    Pilaftsis, Apostolos; Teresi, Daniele

    2016-05-01

    The effective potential of the Standard Model (SM), from three loop order and higher, suffers from infrared (IR) divergences arising from quantum effects due to massless would-be Goldstone bosons associated with the longitudinal polarizations of the W± and Z bosons. Such IR pathologies also hinder accurate evaluation of the two-loop threshold corrections to electroweak quantities, such as the vacuum expectation value of the Higgs field. However, these divergences are an artifact of perturbation theory, and therefore need to be consistently resummed in order to obtain an IR-safe effective potential. The so-called Two-Particle-Irreducible (2PI) effective action provides a rigorous framework to consistently perform such resummations, without the need to resort to ad hoc subtractions or running into the risk of over-counting contributions. By considering the recently proposed symmetry-improved 2PI formalism, we address the problem of the Goldstone-boson IR divergences of the SM effective potential in the gaugeless limit of the theory. In the same limit, we evaluate the IR-safe symmetry-improved 2PI effective potential, after taking into account quantum loops of chiral fermions, as well as the renormalization of spurious custodially breaking effects triggered by fermionic Yukawa interactions. Finally, we compare our results with those obtained with other methods presented in the literature.

  20. Symmetry-improved 2PI approach to the Goldstone-boson IR problem of the SM effective potential

    Directory of Open Access Journals (Sweden)

    Apostolos Pilaftsis

    2016-05-01

    Full Text Available The effective potential of the Standard Model (SM, from three loop order and higher, suffers from infrared (IR divergences arising from quantum effects due to massless would-be Goldstone bosons associated with the longitudinal polarizations of the W± and Z bosons. Such IR pathologies also hinder accurate evaluation of the two-loop threshold corrections to electroweak quantities, such as the vacuum expectation value of the Higgs field. However, these divergences are an artifact of perturbation theory, and therefore need to be consistently resummed in order to obtain an IR-safe effective potential. The so-called Two-Particle-Irreducible (2PI effective action provides a rigorous framework to consistently perform such resummations, without the need to resort to ad hoc subtractions or running into the risk of over-counting contributions. By considering the recently proposed symmetry-improved 2PI formalism, we address the problem of the Goldstone-boson IR divergences of the SM effective potential in the gaugeless limit of the theory. In the same limit, we evaluate the IR-safe symmetry-improved 2PI effective potential, after taking into account quantum loops of chiral fermions, as well as the renormalization of spurious custodially breaking effects triggered by fermionic Yukawa interactions. Finally, we compare our results with those obtained with other methods presented in the literature.

  1. Potential Ergogenic Effects of Saffron.

    Science.gov (United States)

    Meamarbashi, Abbas; Rajabi, Ali

    2016-01-01

    Crocus sativus, commonly known as saffron, is a rich source of carotenoids with many health benefits. The muscular strength, pulmonary function, and reaction time are vital to the athlete's performance, and this study aimed to investigate an ergogenic effect of saffron. Twenty-eight nonactive and healthy male university students were randomly assigned into the saffron (n = 14) and control (n = 15) groups. The experimental group received dried saffron stigma (300 mg/day for 10 days) and the control group received a placebo. After one session, familiarization with the tests, anthropometric parameters, visual and audio reaction times, and the maximum isometric and isotonic forces on a leg press machine were measured accordingly, 1 day before and after the supplementation period. This study shows that 10 days of supplementation with saffron significantly increased (10.1%) the isometric force (p saffron (increase in the forces) may contribute to increase in the muscle mitochondrial biogenesis and positive effect on the motor cortex, both of which may explain faster audio and visual reaction times. Saffron supplementation was also possibly responsible for improvement of muscle blood perfusion and facilitation in the oxygen transport.

  2. Potential Therapeutic Effects of Psilocybin.

    Science.gov (United States)

    Johnson, Matthew W; Griffiths, Roland R

    2017-07-01

    Psilocybin and other 5-hydroxytryptamine2A agonist classic psychedelics have been used for centuries as sacraments within indigenous cultures. In the mid-twentieth century they were a focus within psychiatry as both probes of brain function and experimental therapeutics. By the late 1960s and early 1970s these scientific inquires fell out of favor because classic psychedelics were being used outside of medical research and in association with the emerging counter culture. However, in the twenty-first century, scientific interest in classic psychedelics has returned and grown as a result of several promising studies, validating earlier research. Here, we review therapeutic research on psilocybin, the classic psychedelic that has been the focus of most recent research. For mood and anxiety disorders, three controlled trials have suggested that psilocybin may decrease symptoms of depression and anxiety in the context of cancer-related psychiatric distress for at least 6 months following a single acute administration. A small, open-label study in patients with treatment-resistant depression showed reductions in depression and anxiety symptoms 3 months after two acute doses. For addiction, small, open-label pilot studies have shown promising success rates for both tobacco and alcohol addiction. Safety data from these various trials, which involve careful screening, preparation, monitoring, and follow-up, indicate the absence of severe drug-related adverse reactions. Modest drug-related adverse effects at the time of medication administration are readily managed. US federal funding has yet to support therapeutic psilocybin research, although such support will be important to thoroughly investigate efficacy, safety, and therapeutic mechanisms.

  3. A parametrized optimized effective potential for atoms

    Energy Technology Data Exchange (ETDEWEB)

    Sarsa, A; Galvez, F J; BuendIa, E [Departamento de FIsica Moderna, Facultad de Ciencias, Universidad de Granada, E-18071 Granada (Spain)

    2003-11-28

    The optimized effective potential equations for atoms have been solved by parametrizing the potential. The expansion is tailored to match the known asymptotic behaviour of the effective potential at both short and long distances. Both single configuration and multi-configuration trial wavefunctions are implemented. Applications to several atomic systems are presented, improving on previous works. The results obtained here are very close to those calculated in either the Hartree-Fock (HF) or the multi-configurational HF framework.

  4. Effective potential in the BET formalism

    CERN Document Server

    Bessa, A; Fraga, E S; Gelis, F

    2011-01-01

    We calculate the one-loop effective potential at finite temperature for a system of massless scalar fields with quartic interaction $\\lambda\\phi^4$ in the framework of the boundary effective theory (BET) formalism. The calculation relies on the solution of the classical equation of motion for the field, and Gaussian fluctuations around it. Our result is non-perturbative and differs from the standard one-loop effective potential for field values larger than $T/\\sqrt{\\lambda}$.

  5. Symmetry-Improved 2PI Approach to the Goldstone-Boson IR Problem of the SM Effective Potential

    CERN Document Server

    Pilaftsis, Apostolos

    2015-01-01

    The effective potential of the Standard Model (SM), from three loop order and higher, suffers from infra-red (IR) divergences arising from quantum effects due to massless would-be Goldstone bosons associated with the longitudinal polarizations of the W and Z bosons. Such IR pathologies also hinder accurate evaluation of the two-loop threshold corrections to electroweak quantities, such as the vacuum expectation value of the Higgs field. However, these divergences are an artifact of perturbation theory, and therefore need to be consistently resummed in order to obtain a IR-safe effective potential. The so-called Two-Particle-Irreducible (2PI) effective action provides a rigorous framework to consistently perform such resummations, without the need to resort to ad hoc subtractions or running into the risk of over-counting contributions. By considering the recently proposed symmetry-improved 2PI formalism, we address the problem of the Goldstone-boson IR divergences of the SM effective potential in the gaugeless...

  6. Evidence of a short-range incommensurate d-wave charge order from a fermionic two-loop renormalization group calculation of a 2D model with hot spots

    Energy Technology Data Exchange (ETDEWEB)

    Carvalho, Vanuildo S de [Instituto de Física, Universidade Federal de Goiás, 74.001-970, Goiânia-GO (Brazil); Freire, Hermann, E-mail: hfreire@mit.edu [Instituto de Física, Universidade Federal de Goiás, 74.001-970, Goiânia-GO (Brazil); Department of Physics, Massachusetts Institute of Technology, Cambridge, MA 2139 (United States)

    2014-09-15

    The two-loop renormalization group (RG) calculation is considerably extended here for the two-dimensional (2D) fermionic effective field theory model, which includes only the so-called “hot spots” that are connected by the spin-density-wave (SDW) ordering wavevector on a Fermi surface generated by the 2D t−t{sup ′} Hubbard model at low hole doping. We compute the Callan–Symanzik RG equation up to two loops describing the flow of the single-particle Green’s function, the corresponding spectral function, the Fermi velocity, and some of the most important order-parameter susceptibilities in the model at lower energies. As a result, we establish that–in addition to clearly dominant SDW correlations–an approximate (pseudospin) symmetry relating a short-range incommensurated-wave charge order to the d-wave superconducting order indeed emerges at lower energy scales, which is in agreement with recent works available in the literature addressing the 2D spin-fermion model. We derive implications of this possible electronic phase in the ongoing attempt to describe the phenomenology of the pseudogap regime in underdoped cuprates.

  7. Potential Health Effects from Groundwater Pollution.

    Science.gov (United States)

    Goyer, Robert A.

    1985-01-01

    Discusses the growing awareness of potential toxicological effects of synthetic organic chemicals contaminating groundwater. Problems concerning pesticides, chlorination, epidemiologic studies, cancer, nephrotoxicity, and considerations of risk are addressed. Additional research in this area is advocated. (DH)

  8. Potential environmental effects of controlled thermonuclear reactors

    Energy Technology Data Exchange (ETDEWEB)

    Young, J.R.; Gore, B.F.

    1976-01-01

    The following topics are discussed: (1) the fusion reaction, (2) approach to the environmental analysis, (3) the reference CTR, (4) CTR environmental effects, (5) CTR accident potential, and (6) the advanced CTR. (MOW)

  9. Effective Potential in Noncommutative BTZ Black Hole

    Science.gov (United States)

    Sadeghi, Jafar; Shajiee, Vahid Reza

    2016-02-01

    In this paper, we investigated the noncommutative rotating BTZ black hole and showed that such a space-time is not maximally symmetric. We calculated effective potential for the massive and the massless test particle by geodesic equations, also we showed effect of non-commutativity on the minimum mass of BTZ black hole.

  10. The Two-Loop Anomalous Dimension Matrix for $\\Delta S=1$ Weak Non-Leptonic Decays; 1, ${\\cal O}(\\alpha_s^2)$

    CERN Document Server

    Buras, Andrzej J; Lautenbacher, M E; Weisz, P; Buras, Andrzej J.; Jamin, Matthias; Lautenbacher, Markus E.; Weisz, Peter H.

    1993-01-01

    We calculate the two-loop $10 \\times 10$ anomalous dimension matrix ${\\cal O}(\\alpha_s^{2})$ involving current-current operators, QCD penguin operators, and electroweak penguin operators especially relevant for $\\Delta S=1$ weak non-leptonic decays, but also important for $\\Delta B=1$ decays. The calculation is performed in two schemes for $\\gamma_{5}$: the dimensional regularization scheme with anticommuting $\\gamma_{5}$ (NDR), and in the 't Hooft-Veltman scheme. We demonstrate how a direct calculation of diagrams involving $\\gamma_{5}$ in closed fermion loops can be avoided thus allowing a consistent calculation in the NDR scheme. The compatibility of the results obtained in the two schemes considered is verified and the properties of the resulting matrices are discussed. The two-loop corrections are found to be substantial. The two-loop anomalous dimension matrix ${\\cal O}(\\alpha_e\\alpha_s)$, required for a consistent inclusion of electroweak penguin operators, is presented in a subsequent publication.

  11. Effective potential in density matrix functional theory.

    Science.gov (United States)

    Nagy, A; Amovilli, C

    2004-10-01

    In the previous paper it was shown that in the ground state the diagonal of the spin independent second-order density matrix n can be determined by solving a single auxiliary equation of a two-particle problem. Thus the problem of an arbitrary system with even electrons can be reduced to a two-particle problem. The effective potential of the two-particle equation contains a term v(p) of completely kinetic origin. Virial theorem and hierarchy of equations are derived for v(p) and simple approximations are proposed. A relationship between the effective potential u(p) of the shape function equation and the potential v(p) is established.

  12. The Stark effect in linear potentials

    Energy Technology Data Exchange (ETDEWEB)

    Robinett, R W [Department of Physics, Pennsylvania State University, University Park, PA 16802 (United States)], E-mail: rick@phys.psu.edu

    2010-01-15

    We examine the Stark effect (the second-order shifts in the energy spectrum due to an external constant force) for two one-dimensional model quantum mechanical systems described by linear potentials, the so-called quantum bouncer (defined by V(z) = Fz for z > 0 and V(z) = {infinity} for z < 0) and the symmetric linear potential (given by V(z) = F|z|). We show how straightforward use of the most obvious properties of the Airy function solutions and simple Taylor expansions gives closed form results for the Stark shifts in both systems. These exact results are then compared to other approximation techniques, such as perturbation theory and WKB methods. These expressions add to the small number of closed-form descriptions available for the Stark effect in model quantum mechanical systems.

  13. The Stark effect in linear potentials

    CERN Document Server

    Robinett, R W

    2009-01-01

    We examine the Stark effect (the second-order shift in the energy spectrum due to an external constant force) for two 1-dimensional model quantum mechanical systems described by linear potentials, the so-called quantum bouncer (defined by V(z) = Fz for z>0 and V(z) infinite for z<0) and the symmetric linear potential (given by V(z) = F|z|). We show how straightforward use of the most obvious properties of the Airy function solutions and simple Taylor expansions give closed form results for the Stark shifts in both systems. These exact results are then compared to other approximation techniques, such as perturbation theory and WKB methods. These expressions add to the small number of closed-form descriptions available for the Stark effect in model quantum mechanical systems.

  14. The Stark Effect in Linear Potentials

    Science.gov (United States)

    Robinett, R. W.

    2010-01-01

    We examine the Stark effect (the second-order shifts in the energy spectrum due to an external constant force) for two one-dimensional model quantum mechanical systems described by linear potentials, the so-called quantum bouncer (defined by V(z) = Fz for z greater than 0 and V(z) = [infinity] for z less than 0) and the symmetric linear potential…

  15. Effective Depletion Potential of Colloidal Spheres

    Institute of Scientific and Technical Information of China (English)

    LI Wei-Hua; MA Hong-Ru

    2004-01-01

    @@ A new semianalytical method, which is a combination of the density functional theory with Rosenfeld density functional and the Ornstein-Zernike equation, is proposed for the calculation of the effective depletion potentials between a pair of big spheres immersed in a small hard sphere fluid. The calculated results are almost identical to the integral equation method with the Percus-Yevick approximation, and are also in agreement well with the Monte Carlo simulation results.

  16. Anomalous scaling and large-scale anisotropy in magnetohydrodynamic turbulence: two-loop renormalization-group analysis of the Kazantsev-Kraichnan kinematic model.

    Science.gov (United States)

    Antonov, N V; Gulitskiy, N M

    2012-06-01

    The field theoretic renormalization group and operator product expansion are applied to the Kazantsev-Kraichnan kinematic model for the magnetohydrodynamic turbulence. The anomalous scaling emerges as a consequence of the existence of certain composite fields ("operators") with negative dimensions. The anomalous exponents for the correlation functions of arbitrary order are calculated in the two-loop approximation (second order of the renormalization-group expansion), including the anisotropic sectors. The anomalous scaling and the hierarchy of anisotropic contributions become stronger due to those second-order contributions.

  17. The two-loop sunrise integral around four space-time dimensions and generalisations of the Clausen and Glaisher functions towards the elliptic case

    Science.gov (United States)

    Adams, Luise; Bogner, Christian; Weinzierl, Stefan

    2015-07-01

    We present the result for the finite part of the two-loop sunrise integral with unequal masses in four space-time dimensions in terms of the O ( ɛ0) -part and the O ( ɛ1) -part of the sunrise integral around two space-time dimensions. The latter two integrals are given in terms of elliptic generalisations of Clausen and Glaisher functions. Interesting aspects of the result for the O ( ɛ1 ) -part of the sunrise integral around two space-time dimensions are the occurrence of depth two elliptic objects and the weights of the individual terms.

  18. The two-loop sunrise integral around four space-time dimensions and generalisations of the Clausen and Glaisher functions towards the elliptic case

    CERN Document Server

    Adams, Luise; Weinzierl, Stefan

    2015-01-01

    We present the result for the finite part of the two-loop sunrise integral with unequal masses in four space-time dimensions in terms of the ${\\mathcal O}(\\varepsilon^0)$-part and the ${\\mathcal O}(\\varepsilon^1)$-part of the sunrise integral around two space-time dimensions. The latter two integrals are given in terms of elliptic generalisations of Clausen and Glaisher functions. Interesting aspects of the result for the ${\\mathcal O}(\\varepsilon^1)$-part of the sunrise integral around two space-time dimensions are the occurrence of depth two elliptic objects and the weights of the individual terms.

  19. Taming Infrared Divergences in the Effective Potential

    CERN Document Server

    Elias-Miro, J; Konstandin, T

    2014-01-01

    The Higgs effective potential in the Standard Model (SM), calculated perturbatively, generically suffers from infrared (IR) divergences when the (field-dependent) tree-level mass of the Goldstone bosons goes to zero. Such divergences can affect both the potential and its first derivative and become worse with increasing loop order. In this paper we show that these IR divergences are spurious, we perform a simple resummation of all IR-problematic terms known (up to three loops) and explain how to extend the resummation to cure all such divergences to any order. The method is of general applicability and would work in scenarios other than the SM. Our discussion has some bearing on a scenario recently proposed as a mechanism for gauge mediation of scale breaking in the ultraviolet, in which it is claimed that the low-energy Higgs potential is non-standard. We argue that all non-decoupling effects from the heavy sector can be absorbed in the renormalization of low-energy parameters leading to a SM-like effective ...

  20. Could piracetam potentiate behavioural effects of psychostimulants?

    Science.gov (United States)

    Slais, Karel; Machalova, Alena; Landa, Leos; Vrskova, Dagmar; Sulcova, Alexandra

    2012-08-01

    Press and internet reports mention abuse of nootropic drug piracetam (PIR) in combination with psychostimulants methamphetamine (MET) or 4-methylenedioxymethamphetamine (MDMA). These combinations are believed to produce more profound desirable effects, while decreasing hangover. However, there is a lack of valid experimental studies on such drug-drug interactions in the scientific literature available. Our hypothesis proposes that a functional interaction exists between PIR and amphetamine psychostimulants (MET and MDMA) which can potentiate psychostimulant behavioural effects. Our hypothesis is supported by the results of our pilot experiment testing acute effects of drugs given to mice intraperitoneally (Vehicle, n=12; MET 2.5mg/kg, n=10; MDMA 2.5mg/kg, n=11; PIR 300 mg/kg, n=12; PIR+MET, n=12; PIR+MDMA, n=11) in the Open Field Test (Actitrack, Panlab, Spain). PIR given alone caused no significant changes in mouse locomotor/exploratory behaviour, whereas the same dose combined with either MET or MDMA significantly enhanced their stimulatory effects. Different possible neurobiological mechanism underlying drug-drug interaction of PIR with MET or MDMA are discussed, as modulation of dopaminergic, glutamatergic or cholinergic brain systems. However, the interaction with membrane phospholipids seems as the most plausible mechanism explaining PIR action on activities of neurotransmitter systems. Despite that our behavioural experiment cannot serve for explanation of the pharmacological mechanisms of these functional interactions, it shows that PIR effects can increase behavioural stimulation of amphetamine drugs. Thus, the reported combining of PIR with MET or MDMA by human abusers is not perhaps a coincidental phenomenon and may be based on existing PIR potential to intensify acute psychostimulant effects of these drugs of abuse. Copyright © 2012 Elsevier Ltd. All rights reserved.

  1. Breakdown of Fermi liquid behavior near the hot spots in a two-dimensional model: A two-loop renormalization group analysis

    Energy Technology Data Exchange (ETDEWEB)

    Carvalho, Vanuildo S. de [Instituto de Física, Universidade Federal de Goiás, 74.001-970 Goiânia, GO (Brazil); Freire, Hermann, E-mail: hfreire@mit.edu [Instituto de Física, Universidade Federal de Goiás, 74.001-970 Goiânia, GO (Brazil); Department of Physics, Massachusetts Institute of Technology, Cambridge, MA 02139 (United States)

    2013-10-21

    Motivated by a recent experimental observation of a nodal liquid on both single crystals and thin films of Bi{sub 2}Sr{sub 2}CaCu{sub 2}O{sub 8+} {sub δ} by Chatterjee et al. [Nature Phys. 6 (2010) 99], we perform a field-theoretical renormalization group (RG) analysis of a two-dimensional model such that only eight points located near the “hot spots” on the Fermi surface are retained, which are directly connected by spin density wave ordering wavevector. We derive RG equations up to two-loop order describing the flow of renormalized couplings, quasiparticle weight, several order-parameter response functions, and uniform spin and charge susceptibilities of the model. We find that while the order-parameter susceptibilities investigated here become non-divergent at two loops, the quasiparticle weight vanishes in the low-energy limit, indicating a breakdown of Fermi liquid behavior at this RG level. Moreover, both uniform spin and charge susceptibilities become suppressed in the scaling limit which indicate gap openings in both spin and charge excitation spectra of the model.

  2. Two-Loop Quark Self-Energy in a New Formalism; 2, Renormalization of the Quark Propagator in the Light-Cone Gauge

    CERN Document Server

    Leibbrandt, George; Leibbrandt, George; Williams, Jimmy D.

    2000-01-01

    The complete two-loop correction to the quark propagator, consisting of the spider, rainbow, gluon bubble and quark bubble diagrams, is evaluated in the noncovariant light-cone gauge (lcg). (The overlapping self-energy diagram had already been computed.) The chief technical tools include the powerful matrix integration technique, the n^*-prescription for the spurious poles of 1/qn, and the detailed analysis of the boundary singularities in five- and six-dimensional parameter space. It is shown that the total divergent contribution to the two-loop correction Sigma_2 contains both covariant and noncovariant components, and is a local function of the external momentum p, even off the mass-shell, as all nonlocal divergent terms cancel exactly. Consequently, both the quark mass and field renormalizations are local. The structure of Sigma_2 implies a quark mass counterterm of the form $\\delta m (lcg) = m\\tilde\\alpha_s C_F(3+\\tilde\\alpha_sW) + {\\rm O} (\\tilde\\alpha_s^3)$, the dimensional regulator epsilon, and on th...

  3. Two-loop quark self-energy in a new formalism; 2, Renormalization of the quark propagator in the light-cone gauge

    CERN Document Server

    Leibbrandt, G

    2000-01-01

    For pt.I see ibid., vol.440, p.537-602, 1995. The complete two-loop correction to the quark propagator, consisting of the spider, rainbow, gluon bubble and quark bubble diagrams, is evaluated in the non-covariant light-cone gauge (LCG), n.A/sup a/(x)=0, n/sup 2/=0. (The overlapping self-energy diagram had already been computed.) The chief technical tools include the powerful matrix integration technique, the n*/sub mu /-prescription for the spurious poles of (q.n)/sup -1/, and the detailed analysis of the boundary singularities in five- and six-dimensional parameter space. It is shown that the total divergent contribution to the two-loop correction Sigma /sub 2/ contains both covariant and non-covariant components, and is a local function of the external momentum p, even off the mass-shell, as all non-local divergent terms cancel exactly. Consequently, both the quark mass and field renormalizations are local. The structure of Sigma /sub 2/ implies a quark mass counterterm of the form delta m(LCG)=m alpha /sub...

  4. Effective potential evaluations in a modified PQCD

    Energy Technology Data Exchange (ETDEWEB)

    Cabo Montes de Oca, A.; Martinez-Pedrera, D. [International Center for Theoretical Physics, Trieste (Italy); Instituto de Cibernetica, Matematica y Fisica, Group of Theoretical Physics, La Habana (Cuba)

    2006-08-15

    A procedure discussed in a previous work for properly defining the Feynman diagrams at any number of loops in a modified version of PQCD, is employed here to evaluate some zero- and one-loop corrections to the effective potential, as functions of the gluon and quark condensate parameters. The calculated terms indicate an instability of massless QCD under the development of quark condensates even in the absence of the gluon one. Therefore, a mechanism is suggested for the dynamical generation of quark masses and condensates. The absence of indications coming from lattice calculations to this possibility could be determined by the current limitations in treating fermion determinants. (orig.)

  5. Finding quantum effects in strong classical potentials

    Science.gov (United States)

    Hegelich, B. Manuel; Labun, Lance; Labun, Ou Z.

    2017-06-01

    The long-standing challenge to describing charged particle dynamics in strong classical electromagnetic fields is how to incorporate classical radiation, classical radiation reaction and quantized photon emission into a consistent unified framework. The current, semiclassical methods to describe the dynamics of quantum particles in strong classical fields also provide the theoretical framework for fundamental questions in gravity and hadron-hadron collisions, including Hawking radiation, cosmological particle production and thermalization of particles created in heavy-ion collisions. However, as we show, these methods break down for highly relativistic particles propagating in strong fields. They must therefore be improved and adapted for the description of laser-plasma experiments that typically involve the acceleration of electrons. Theory developed from quantum electrodynamics, together with dedicated experimental efforts, offer the best controllable context to establish a robust, experimentally validated foundation for the fundamental theory of quantum effects in strong classical potentials.

  6. Effective field theory approaches for tensor potentials

    Energy Technology Data Exchange (ETDEWEB)

    Jansen, Maximilian

    2016-11-14

    Effective field theories are a widely used tool to study physical systems at low energies. We apply them to systematically analyze two and three particles interacting via tensor potentials. Two examples are addressed: pion interactions for anti D{sup 0}D{sup *0} scattering to dynamically generate the X(3872) and dipole interactions for two and three bosons at low energies. For the former, the one-pion exchange and for the latter, the long-range dipole force induce a tensor-like structure of the potential. We apply perturbative as well as non-perturbative methods to determine low-energy observables. The X(3872) is of major interest in modern high-energy physics. Its exotic characteristics require approaches outside the range of the quark model for baryons and mesons. Effective field theories represent such methods and provide access to its peculiar nature. We interpret the X(3872) as a hadronic molecule consisting of neutral D and D{sup *} mesons. It is possible to apply an effective field theory with perturbative pions. Within this framework, we address chiral as well as finite volume extrapolations for low-energy observables, such as the binding energy and the scattering length. We show that the two-point correlation function for the D{sup *0} meson has to be resummed to cure infrared divergences. Moreover, next-to-leading order coupling constants, which were introduced by power counting arguments, appear to be essential to renormalize the scattering amplitude. The binding energy as well as the scattering length display a moderate dependence on the light quark masses. The X(3872) is most likely deeper bound for large light quark masses. In a finite volume on the other hand, the binding energy significantly increases. The dependence on the light quark masses and the volume size can be simultaneously obtained. For bosonic dipoles we apply a non-perturbative, numerical approach. We solve the Lippmann-Schwinger equation for the two-dipole system and the Faddeev

  7. Maximal Unitarity at Two Loops

    CERN Document Server

    Kosower, David A

    2012-01-01

    We show how to compute the coefficients of the double box basis integrals in a massless four-point amplitude in terms of tree amplitudes. We show how to choose suitable multidimensional contours for performing the required cuts, and derive consistency equations from the requirement that integrals of total derivatives vanish. Our formulae for the coefficients can be used either analytically or numerically.

  8. Effects of electron emission on sheath potential

    Science.gov (United States)

    Dow, Ansel; Khrabrov, Alexander; Kaganovich, Igor; Schamis, Hanna

    2015-11-01

    We investigate the potential profile of a sheath under the influence of surface electron emission. The plasma and sheath profiles are simulated using the Large Scale Plasma (LSP) particle-in-cell code. Using one dimensional models we corroborate the analytical relationship between sheath potential and plasma electron and emitted electron temperatures derived earlier. This work was made possible by funding from the Department of Energy for the Summer Undergraduate Laboratory Internship (SULI) program. This work is supported by the US DOE Contract No. DE-AC02-09CH11466.

  9. System-Level Heat Transfer Analysis, Thermal- Mechanical Cyclic Stress Analysis, and Environmental Fatigue Modeling of a Two-Loop Pressurized Water Reactor. A Preliminary Study

    Energy Technology Data Exchange (ETDEWEB)

    Mohanty, Subhasish [Argonne National Lab. (ANL), Argonne, IL (United States); Soppet, William [Argonne National Lab. (ANL), Argonne, IL (United States); Majumdar, Saurin [Argonne National Lab. (ANL), Argonne, IL (United States); Natesan, Ken [Argonne National Lab. (ANL), Argonne, IL (United States)

    2015-01-03

    This report provides an update on an assessment of environmentally assisted fatigue for light water reactor components under extended service conditions. This report is a deliverable in April 2015 under the work package for environmentally assisted fatigue under DOE's Light Water Reactor Sustainability program. In this report, updates are discussed related to a system level preliminary finite element model of a two-loop pressurized water reactor (PWR). Based on this model, system-level heat transfer analysis and subsequent thermal-mechanical stress analysis were performed for typical design-basis thermal-mechanical fatigue cycles. The in-air fatigue lives of components, such as the hot and cold legs, were estimated on the basis of stress analysis results, ASME in-air fatigue life estimation criteria, and fatigue design curves. Furthermore, environmental correction factors and associated PWR environment fatigue lives for the hot and cold legs were estimated by using estimated stress and strain histories and the approach described in NUREG-6909. The discussed models and results are very preliminary. Further advancement of the discussed model is required for more accurate life prediction of reactor components. This report only presents the work related to finite element modelling activities. However, in between multiple tensile and fatigue tests were conducted. The related experimental results will be presented in the year-end report.

  10. Effect of Parabolic Potential on Bipolaron

    Institute of Scientific and Technical Information of China (English)

    RUANYong-Hong; CHENQing-Hu; JIAOZheng-Kuan

    2004-01-01

    We apply a Feynman path-integral variational approach combining with the average for the relative motion to study the stability of bipolaron in a quantum dot. The binding energy is calculated in different parameters. We find that an optimum quantum potential favors the formation of bipolaron. Compared with other methods in literature, the present approach is better than Laudau Pekar one in all coupling regime and full path-integral one in the strong coupling regime.

  11. Effect of Parabolic Potential on Bipolaron

    Institute of Scientific and Technical Information of China (English)

    RUAN Yong-Hong; CHEN Qing-Hu; JIAO Zheng-Kuan

    2004-01-01

    We apply a Feynman path-integral variational approach combining with the average for the relative motion to study the stability of bipolaron in a quantum dot. The binding energy is calculated in different parameters. We find that an optimum quantum potential favors the formation of bipolaron. Compared with other methods in literature, the present pproach is better than Laudau-Pekar one in all coupling regime and full path-integral one in the strong coupling regime.

  12. Potential negative ecological effects of corridors.

    Science.gov (United States)

    Haddad, Nick M; Brudvig, Lars A; Damschen, Ellen I; Evans, Daniel M; Johnson, Brenda L; Levey, Douglas J; Orrock, John L; Resasco, Julian; Sullivan, Lauren L; Tewksbury, Josh J; Wagner, Stephanie A; Weldon, Aimee J

    2014-10-01

    Despite many studies showing that landscape corridors increase dispersal and species richness for disparate taxa, concerns persist that corridors can have unintended negative effects. In particular, some of the same mechanisms that underlie positive effects of corridors on species of conservation interest may also increase the spread and impact of antagonistic species (e.g., predators and pathogens), foster negative effects of edges, increase invasion by exotic species, increase the spread of unwanted disturbances such as fire, or increase population synchrony and thus reduce persistence. We conducted a literature review and meta-analysis to evaluate the prevalence of each of these negative effects. We found no evidence that corridors increase unwanted disturbance or non-native species invasion; however, these have not been well-studied concerns (1 and 6 studies, respectively). Other effects of corridors were more often studied and yielded inconsistent results; mean effect sizes were indistinguishable from zero. The effect of edges on abundances of target species was as likely to be positive as negative. Corridors were as likely to have no effect on antagonists or population synchrony as they were to increase those negative effects. We found 3 deficiencies in the literature. First, despite studies on how corridors affect predators, there are few studies of related consequences for prey population size and persistence. Second, properly designed studies of negative corridor effects are needed in natural corridors at scales larger than those achievable in experimental systems. Third, studies are needed to test more targeted hypotheses about when corridor-mediated effects on invasive species or disturbance may be negative for species of management concern. Overall, we found no overarching support for concerns that construction and maintenance of habitat corridors may result in unintended negative consequences. Negative edge effects may be mitigated by widening

  13. Cropping system effects on wind erosion potential

    Science.gov (United States)

    Wind erosion of soil is a destructive process impacting crop productivity and human health and safety. The mechanics of wind erosion and soil properties that influence erosion are well understood. Less well-studied are the effects that cropping intensity has upon those soil properties. We collected ...

  14. The potential health effects of dietary phytoestrogens

    NARCIS (Netherlands)

    Rietjens, Ivonne M.C.M.; Louisse, Jochem; Beekmann, Karsten

    2017-01-01

    Phytoestrogens are plant-derived dietary compounds with structural similarity to 17-β-oestradiol (E2), the primary female sex hormone. This structural similarity to E2 enables phytoestrogens to cause (anti)oestrogenic effects by binding to the oestrogen receptors. The aim of the present review is to

  15. The potential health effects of dietary phytoestrogens

    NARCIS (Netherlands)

    Rietjens, Ivonne M.C.M.; Louisse, Jochem; Beekmann, Karsten

    2016-01-01

    Phytoestrogens are plant-derived dietary compounds with structural similarity to 17-β-oestradiol (E2), the primary female sex hormone. This structural similarity to E2 enables phytoestrogens to cause (anti)oestrogenic effects by binding to the oestrogen receptors. The aim of the present review is

  16. Genetic effects and potential parents in cowpea

    Directory of Open Access Journals (Sweden)

    Francisco Tiago Cunha Dias

    2016-11-01

    Full Text Available Six cowpea genotypes and their F2 hybrid combinations were evaluated for general and specific combining ability. The Griffing’s diallel cross design, Method 2, and mixed model B were used. The genotypes and hybrids differed statistically (p <0.01 for the 10 studied traits. With regard to the general and specific combining ability, there were statistical differences at 1% probability for all traits. The presence of additive and non-additive gene effects paves the way for breeding new hybrid cultivars. However, additive gene effects were predominant in the trait expression. Genotypes CE-542, CE-954 and CE-796 were identified as the most promising of the test group for inclusion in cowpea breeding programs.

  17. Potential beneficial effects of garlic in oncohematology.

    Science.gov (United States)

    Miroddi, M; Calapai, F; Calapai, G

    2011-06-01

    The use of non-conventional medicines, especially herbal medicine, is common in patients with cancers including haematologic malignancies. Diet components may also modify the risk of cancer through the influence on multiple processes, including DNA repair, cell proliferation and apoptosis. Garlic (Allium sativum), considered either food or herbal medicine, possesses antimutagenic and antiproliferative properties that can be used in anticancer interventions. We analyzed literature data on effects of garlic and garlic compounds which can serve as basic information to design clinical approach in oncohematology. Garlic contains water soluble and oil-soluble sulfur compounds. The latter are responsible for anticancer effects exerted through multiple mechanisms such as: inhibition of metabolic carcinogenic activation, arrest of cell cycle, antioxidant and pro-apoptotic action. Evidence about the effects of main sulfur compounds diallyl sulfide (DAS), diallyl disulfide (DADS), diallyl trisulfide (DATS), ajoene and S-allylmercaptocysteine (SAMC) in oncohematology was described. Our research highlights that data on garlic in oncohematology are essentially represented by pre-clinical studies. Although these studies must be considered as preliminary, they provided insight into biological activities of garlic compounds and support a rationale for the use of substances such as DAS, DADS, DATS and ajoene as promising anticancer agents in oncohematology.

  18. Potential effect of ultrasound on carbohydrates.

    Science.gov (United States)

    Bera, Smritilekha; Mondal, Dhananjoy; Martin, Jacob T; Singh, Man

    2015-06-17

    The use of ultrasound has emerged as one of the most useful alternative energy sources for the synthesis of carbohydrate-derived biologically and pharmaceutically potential compounds. Spectacular advances have been made in the field of sonication-assisted organic reactions, which are known for producing superior yields, enhanced reactivity of the reactant, improved stereoselectivity, and shortened reaction times. Orthogonal protection-deprotection reactions and/or modification and manipulation of functional groups in carbohydrates are common synthetic steps in carbohydrate chemistry. These reaction steps can be driven by the ultrasonic energy generated by acoustic cavitation via the formation and subsequent collapse of ultrasound-induced bubbles. The ultrasound-assisted synthesis of differently functionalised monosaccharides is useful in a wide variety of applications of carbohydrate chemistry such as the glycosylation of oligosaccharides, one pot domino reactions, thioglycoside syntheses, azidoglycoside syntheses, 1,3-dipolar cycloaddition reactions, and syntheses of natural products. This review article covers ultrasound-mediated reactions on carbohydrates that have been described in the literature since 2000.

  19. Effective Kratzer and Coulomb potentials as limit cases of a multiparameter exponential-type potential

    Energy Technology Data Exchange (ETDEWEB)

    García-Ravelo, J., E-mail: g.ravelo@hotmail.com [Departamento de Física, Escuela Superior de Física y Matemáticas, Instituto Politécnico Nacional, Edificio 9, Unidad Profesional Adolfo López Mateos, México D.F., 07738 (Mexico); Menéndez, A.; García-Martínez, J. [Departamento de Física, Escuela Superior de Física y Matemáticas, Instituto Politécnico Nacional, Edificio 9, Unidad Profesional Adolfo López Mateos, México D.F., 07738 (Mexico); Schulze-Halberg, A. [Department of Mathematics and Actuarial Science and Department of Physics, Indiana University Northwest, 3400 Broadway, Gary, IN 46408 (United States)

    2014-06-13

    We show that the effective Kratzer and Coulomb potentials can be obtained by taking particular limits of a multiparameter exponential potential that was studied recently. Moreover, we demonstrate that the bound state solutions of the exponential potential reduce correctly to their well-known counterparts associated with the Kratzer and Coulomb potentials. As a byproduct, we obtain a new limit relation for the hypergeometric function. - Highlights: • Kratzer and Coulomb potentials are limit cases of an exponential-type potential. • From exact s-waves, approximate solutions for l-waves are obtained. • l-waves of the potential tend to the solutions of the Kratzer and Coulomb potentials. • A non-evident identity between hypergeometric functions is demonstrated.

  20. Beyond the Coleman–Weinberg Effective Potential

    CERN Document Server

    CERN. Geneva

    2015-01-01

    The Two-Particle-Irreducible (2PI) formalism as introduced by Cornwall, Jackiw and Tomboulis provides a systematic analytic approach to consistently describing non-perturbative phenomena in Quantum Field Theory. In spite of its great success, one major problem of the 2PI approach is that its loopwise expansion gives rise to residual violations of symmetries and hence to massive Goldstone bosons in the spontaneously broken phase of the theory. In my talk I will present a novel symmetry-improved 2PI formalism which consistently encodes global symmetries in a loopwise expansion. Unlike other methods, I will illustrate how the symmetry-improved 2PI effective action satisfies a number of important field-theoretic properties, such as the masslessness of the Goldstone boson and the fact that the phase transition is of second order in O(N) theories, already in the Hartree-Fock approximation. After taking the sunset diagrams into account, I show how the symmetry-improved 2PI approach properly describe...

  1. Matter-wave bright solitons in effective bichromatic lattice potentials

    Indian Academy of Sciences (India)

    Golam Ali Sekh

    2013-08-01

    Matter-wave bright solitons in bichromatic lattice potentials are considered and their dynamics for different lattice environments are studied. Bichromatic potentials are created from superpositions of (i) two linear optical lattices and (ii) a linear and a nonlinear optical lattice. Effective potentials are found for the solitons in both bichromatic lattices and a comparative study is done on the dynamics of solitons with respect to the effective potentials. The effects of dispersion on solitons in bichromatic lattices are studied and it is found that the dispersive spreading can be minimized by appropriate combinations of lattice and interaction parameters. Stability of nondispersive matter-wave solitons is checked from phase portrait analysis.

  2. Ultrasoft renormalization of the potentials in vNRQCD

    Energy Technology Data Exchange (ETDEWEB)

    Stahlhofen, Maximilian Horst

    2009-02-18

    The effective field theory vNRQCD allows to describe among others the production of top-antitop pairs in electron-positron collisions at threshold, i.e. with very small relative velocity {upsilon} << 1 of the quarks. Potentially large logarithms {proportional_to} ln {upsilon} are systematically summed up and lead to a scale dependence of the Wilson coefficients of the theory. The missing contributions to the cross section {sigma}(e{sup +}e{sup -} {yields} t anti t) in the resonance region at NNLL level are the so-called mixing contributions to the NNLL anomalous dimension of the S-wave production/annihilation current of the topquark pair. To calculate these one has to know the NLL renormalization group running of so-called potentials (4-quark operators). The dominant contributions to the anomalous dimension of these potentials come from vNRQCD diagrams with ultrasoft gluon loops. The aim of this thesis is to derive the complete ultrasoft NLL running of the relevant potentials. For that purpose the UV divergent parts of about 10{sup 4} two-loop diagrams are determined. Technical and conceptional issues are discussed. Some open questions related to the calculation of the non-Abelian two-loop diagrams arise. Preliminary results are analysed with regard to the consequences for the mentioned cross section and its theoretical uncertainty. (orig.)

  3. Can the Renormalization Group Improved Effective Potential be used to estimate the Higgs Mass in the Conformal Limit of the Standard Model?

    CERN Document Server

    Chishtie, F A; Jia, J; Mann, R B; McKeon, D G C; Sherry, T N; Steele, T G

    2010-01-01

    We consider the effective potential $V$ in the standard model with a single Higgs doublet in the limit that the only mass scale $\\mu$ present is radiatively generated. Using a technique that has been shown to determine $V$ completely in terms of the renormalization group (RG) functions when using the Coleman-Weinberg (CW) renormalization scheme, we first sum leading-log (LL) contributions to $V$ using the one loop RG functions, associated with five couplings (the top quark Yukawa coupling $x$, the quartic coupling of the Higgs field $y$, the $SU(3)$ gauge coupling $z$, and the $SU(2) \\times U(1)$ couplings $r$ and $s$). We then employ the two loop RG functions with the three couplings $x$, $y$, $z$ to sum the next-to-leading-log (NLL) contributions to $V$ and then the three to five loop RG functions with one coupling $y$ to sum all the $N^2LL \\ldots N^4LL$ contributions to $V$. In order to compute these sums, it is necessary to convert those RG functions that have been originally computed explicitly in the mi...

  4. Effect of the earth's ellipticity on the lunar tidal potential

    Science.gov (United States)

    Dahlen, F. A.

    1993-01-01

    The earth's orbital acceleration about the moon is influenced by its ellipticity. In this paper it shown that the ellipticity affects tidal gravity by contributing directly to the lunar tide-generating potential (in addition to effecting the elastic-gravitational response of the solid earth and oceans to this potential).

  5. Effective potentials for atom-atom interaction at low temperatures

    OpenAIRE

    Gao, Bo

    2002-01-01

    We discuss the concept and design of effective atom-atom potentials that accurately describe any physical processes involving only states around the threshold. The existence of such potentials gives hope to a quantitative, and systematic, understanding of quantum few-atom and quantum many-atom systems at relatively low temperatures.

  6. Electric potential invariants and ions-in-molecules effective potentials for molecular Rydberg states

    Science.gov (United States)

    Coy, Stephen L.; Grimes, David D.; Zhou, Yan; Field, Robert W.; Wong, Bryan M.

    2016-12-01

    The dependence of multipole moments and polarizabilities on external fields appears in many applications including biomolecular molecular mechanics, optical non-linearity, nanomaterial calculations, and the perturbation of spectroscopic signatures in atomic clocks. Over a wide range of distances, distributed multipole and polarizability potentials can be applied to obtain the variation of atom-centered atoms-in-molecules electric properties like bonding-quenched polarizability. For cylindrically symmetric charge distributions, we examine single-center and atom-centered effective polarization potentials in a non-relativistic approximation for Rydberg states. For ions, the multipole expansion is strongly origin-dependent, but we note that origin-independent invariants can be defined. The several families of invariants correspond to optimized representations differing by origin and number of terms. Among them, a representation at the center of dipole polarizability optimizes the accuracy of the potential with terms through 1/r4. We formulate the single-center expansion in terms of polarization-modified effective multipole moments, defining a form related to the source-multipole expansion of Brink and Satchler. Atom-centered potentials are an origin independent alternative but are limited both by the properties allowed at each center and by the neglected effects like bond polarizability and charge flow. To enable comparisons between single-center effective potentials in Cartesian or spherical form and two-center effective potentials with differing levels of mutual induction between atomic centers, we give analytical expressions for the bond-length and origin-dependence of multipole and polarizability terms projected in the multipole and polarizability expansion of Buckingham. The atom-centered potentials can then be used with experimental data and ab initio calculations to estimate atoms-in-molecules properties. Some results are given for BaF+ and HF showing the

  7. Trial Study of Vibration-Induced Effects on Spontaneous Potential

    Institute of Scientific and Technical Information of China (English)

    SunWeibin; QiuWeiting; HeZhanxiang

    2003-01-01

    Vibratory excitation generates not only reflections and refractions of wave fields on the subsurface interfaces but also electromagnetic waves with different frequencies. In this paper we address the vibration-induced effects on the spontaneous potential field. The effects of controllable vibration on the spontaneous potential field were studied under real field geologic conditions. Experimental data confirmed that the vibration-induced effects on the spontaneous potential field do exist under field conditions. Monitoring records over a long time interval showed that there existed three information zones in the vibration-induced effects on spontaneous potential field:These are the signal-variant zone, the extreme-stable zone and the relaxation-recovery zone. Combined with different well-site data, it was concluded that the time-variant features of the anomalies in the information zones was closely related to the properties of the subsurface liquid (oil and water).

  8. Emerging evidence of ozone metabolic effects and potential mechanisms

    Science.gov (United States)

    SOT 2014 Abstract: Invitational Emerging evidence of ozone metabolic effects and potential mechanisms U.P. Kodavanti NHEERL, USEPA, Research Triangle Park, NC Recent evidence suggests that air pollutants are linked to metabolic syndrome and impact several key metabolic proce...

  9. Effect of Ionic Diffusion on Extracellular Potentials in Neural Tissue.

    Directory of Open Access Journals (Sweden)

    Geir Halnes

    2016-11-01

    Full Text Available Recorded potentials in the extracellular space (ECS of the brain is a standard measure of population activity in neural tissue. Computational models that simulate the relationship between the ECS potential and its underlying neurophysiological processes are commonly used in the interpretation of such measurements. Standard methods, such as volume-conductor theory and current-source density theory, assume that diffusion has a negligible effect on the ECS potential, at least in the range of frequencies picked up by most recording systems. This assumption remains to be verified. We here present a hybrid simulation framework that accounts for diffusive effects on the ECS potential. The framework uses (1 the NEURON simulator to compute the activity and ionic output currents from multicompartmental neuron models, and (2 the electrodiffusive Kirchhoff-Nernst-Planck framework to simulate the resulting dynamics of the potential and ion concentrations in the ECS, accounting for the effect of electrical migration as well as diffusion. Using this framework, we explore the effect that ECS diffusion has on the electrical potential surrounding a small population of 10 pyramidal neurons. The neural model was tuned so that simulations over ∼100 seconds of biological time led to shifts in ECS concentrations by a few millimolars, similar to what has been seen in experiments. By comparing simulations where ECS diffusion was absent with simulations where ECS diffusion was included, we made the following key findings: (i ECS diffusion shifted the local potential by up to ∼0.2 mV. (ii The power spectral density (PSD of the diffusion-evoked potential shifts followed a 1/f2 power law. (iii Diffusion effects dominated the PSD of the ECS potential for frequencies up to several hertz. In scenarios with large, but physiologically realistic ECS concentration gradients, diffusion was thus found to affect the ECS potential well within the frequency range picked up in

  10. The effect of jogging on P300 event related potentials.

    Science.gov (United States)

    Nakamura, Y; Nishimoto, K; Akamatu, M; Takahashi, M; Maruyama, A

    1999-03-01

    Physical exercise has beneficial effects not only on cardiovascular system and fat metabolism, may also directly effect the cognitive process. We studied the effect of physical exercise on cognitive processes by measuring the P300 event related-potential (ERP) after jogging. Seven well-trained joggers were enrolled in this study and the P300 potentials using auditory oddball paradigm. ERPs were measured before and after 30 minutes of jogging. The amplitude of the P300 significantly increased after jogging compared to values recorded before jogging. These findings suggest that jogging has the effect of facilitating cognitive processes involved in generation of the P300.

  11. Instanton effects on the heavy-quark static potential

    Science.gov (United States)

    Yakhshiev, U. T.; Kim, Hyun-Chul; Turimov, B.; Musakhanov, M. M.; Hiyama, Emiko

    2017-08-01

    We investigate instanton effects on the heavy-quark potential, including its spin-dependent part, based on the instanton liquid model. Starting with the central potential derived from the instanton vacuum, we obtain the spin-dependent part of the heavy-quark potential. We discuss the results of the heavy-quark potential from the instanton vacuum. Finally, we solve the nonrelativistic two-body problem, associated with the heavy-quark potential from the instanton vacuum. The instanton effects on the quarkonia spectra are marginal but are required for quantitative description of the spectra. Supported by Basic Science Research Program through the National Research Foundation (NRF) of Korea funded by the Korean government (Ministry of Education, Science and Technology, MEST), Grant Numbers 2016R1D1A1B03935053 (UY) and 2015R1D1A1A01060707 (HChK) and The work was also partly Supported by RIKEN iTHES Project

  12. Effective polarization interaction potentials of the partially ionized dense plasma

    Energy Technology Data Exchange (ETDEWEB)

    Ramazanov, T S [IETP, Al Farabi Kazakh National University, Tole Bi 96a, 050012 Almaty (Kazakhstan); Dzhumagulova, K N [IETP, Al Farabi Kazakh National University, Tole Bi 96a, 050012 Almaty (Kazakhstan); Omarbakiyeva, Yu A [IETP, Al Farabi Kazakh National University, Tole Bi 96a, 050012 Almaty (Kazakhstan); Roepke, G [Institute of Physics, University of Rostock, D-18051 Rostock (Germany)

    2006-04-28

    The effective polarization interaction potential between charged and neutral particles is considered for a partially ionized plasma. This pseudopotential is deduced taking into account quantum-mechanical effects at short distances as well as screening effects at large distances. Furthermore, a cutoff radius is obtained using a modified effective-range theory. Explicit results for parameters describing the interaction of the atom with charged particles are given.

  13. Effective Form of Reproducing the Total Financial Potential of Ukraine

    Directory of Open Access Journals (Sweden)

    Portna Oksana V.

    2015-03-01

    Full Text Available Development of scientific principles of reproducing the total financial potential of the country and its effective form is an urgent problem both in theoretical and practical aspects of the study, the solution of which is intended to ensure the active mobilization and effective use of the total financial potential of Ukraine, and as a result — its expanded reproduction as well, which would contribute to realization of the internal capacities for stabilization of the national economy. The purpose of the article is disclosing the essence of the effective form of reproducing the total financial potential of the country, analyzing the results of reproducing the total financial potential of Ukraine. It has been proved that the basis for the effective form of reproducing the total financial potential of the country is the volume and flow of resources, which are associated with the «real» economy, affect the dynamics of GDP and define it, i.e. resource and process forms of reproducing the total financial potential of Ukraine (which precede the effective one. The analysis of reproducing the total financial potential of Ukraine has shown that in the analyzed period there was an increase in the financial possibilities of the country, but steady dynamics of reduction of the total financial potential was observed. If we consider the amount of resources involved in production, creating a net value added and GDP, it occurs on a restricted basis. Growth of the total financial potential of Ukraine is connected only with extensive quantitative factors rather than intensive qualitative changes.

  14. Higgs effective potential in a perturbed Robertson-Walker background

    CERN Document Server

    Maroto, Antonio L

    2014-01-01

    We calculate the one-loop effective potential of a scalar field in a Robertson-Walker background with scalar metric perturbations. A complete set of orthonormal solutions of the perturbed equations is obtained by using the adiabatic approximation for comoving observers. After analyzing the problem of renormalization in inhomogeneous backgrounds, we get the explicit contribution of metric perturbations to the effective potential. We apply these results to the Standard Model Higgs effective potential and evaluate the effects of metric perturbations on the Higgs vacuum expectation value. Space-time variations are found, which are proportional to the gravitational slip parameter, with a typical amplitude of the order of $\\Delta\\phi/\\phi\\simeq 10^{-11}$ on cosmological scales. We also discuss possible astrophysical signatures in the Solar System and in the Milky Way that could open new possibilities to explore the symmetry breaking sector of the electroweak interactions.

  15. Effective attractive potential between identical dielectric molecules via Lifshitz theory

    Institute of Scientific and Technical Information of China (English)

    陈来文; 李椿萱

    2001-01-01

    A general theory of Van der Waals forces developed by Lifshitz based on quantum electrodynamics theory is applied in the range Rλ0 (where the Casimir effects may be neglected) to construct Van der Waals attractive potential between identical dielectric molecules in rarefied media in order that the effective attractive potential between the like-molecules (including the repeat units) is offered. A closed form solution for the integral formulation of the attractive potential between like-particles is first obtained based on certain assumptions made in this work. On the basis of the theory of electric polarization, the derived expression in terms of bulk properties is then compared with the well-known London formula, the former differs from the latter only by the factor (4)/(π)or (4)/(π)(ε∞+2)/(3)2. The validity of the effective potential can be verified by testing cases composed of several types of dielectric materials. The computed results are presented in this paper, and comparisons with the results computed by London dispersion formula, as well as the recommended values in virtue of the experimental and theoretical techniques, are also presented. The effective potential of polyethylene is also computed to demonstrate the effectiveness of the developed model, and it is found that the computed well depth fall within a reasonable range of accuracy.

  16. Density functional theory based generalized effective fragment potential method

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, Kiet A., E-mail: kiet.nguyen@wpafb.af.mil, E-mail: ruth.pachter@wpafb.af.mil [Air Force Research Laboratory, Wright-Patterson Air Force Base, Ohio 45433 (United States); UES, Inc., Dayton, Ohio 45432 (United States); Pachter, Ruth, E-mail: kiet.nguyen@wpafb.af.mil, E-mail: ruth.pachter@wpafb.af.mil [Air Force Research Laboratory, Wright-Patterson Air Force Base, Ohio 45433 (United States); Day, Paul N. [Air Force Research Laboratory, Wright-Patterson Air Force Base, Ohio 45433 (United States); General Dynamics Information Technology, Inc., Dayton, Ohio 45431 (United States)

    2014-06-28

    We present a generalized Kohn-Sham (KS) density functional theory (DFT) based effective fragment potential (EFP2-DFT) method for the treatment of solvent effects. Similar to the original Hartree-Fock (HF) based potential with fitted parameters for water (EFP1) and the generalized HF based potential (EFP2-HF), EFP2-DFT includes electrostatic, exchange-repulsion, polarization, and dispersion potentials, which are generated for a chosen DFT functional for a given isolated molecule. The method does not have fitted parameters, except for implicit parameters within a chosen functional and the dispersion correction to the potential. The electrostatic potential is modeled with a multipolar expansion at each atomic center and bond midpoint using Stone's distributed multipolar analysis. The exchange-repulsion potential between two fragments is composed of the overlap and kinetic energy integrals and the nondiagonal KS matrices in the localized molecular orbital basis. The polarization potential is derived from the static molecular polarizability. The dispersion potential includes the intermolecular D3 dispersion correction of Grimme et al. [J. Chem. Phys. 132, 154104 (2010)]. The potential generated from the CAMB3LYP functional has mean unsigned errors (MUEs) with respect to results from coupled cluster singles, doubles, and perturbative triples with a complete basis set limit (CCSD(T)/CBS) extrapolation, of 1.7, 2.2, 2.0, and 0.5 kcal/mol, for the S22, water-benzene clusters, water clusters, and n-alkane dimers benchmark sets, respectively. The corresponding EFP2-HF errors for the respective benchmarks are 2.41, 3.1, 1.8, and 2.5 kcal/mol. Thus, the new EFP2-DFT-D3 method with the CAMB3LYP functional provides comparable or improved results at lower computational cost and, therefore, extends the range of applicability of EFP2 to larger system sizes.

  17. Effect of functionalization on drug delivery potential of carbon nanotubes.

    Science.gov (United States)

    Sharma, Sonam; Mehra, Neelesh Kumar; Jain, Keerti; Jain, Narendra Kumar

    2016-12-01

    The main aim of the present investigation was to explore the effect of functionalization on drug delivery potential of carbon nanotubes (CNTs) and to compare the in vitro and in vivo cancer targeting potential of doxorubicin HCL (DOX)-loaded ox-/multi-walled CNTs (MWCNTs), DOX-loaded PEG-MWCNTs and DOX-loaded FA-PEG-MWCNTs. The DOX/PEG-FA-MWCNTs showed enhanced cytotoxicity and were most preferentially taken up by the cancerous cells. The obtained results also support the extended resistance time and sustained release profile of drug-loaded surface-engineered MWCNTs. Overall, we concluded that the developed MWCNTs nanoformulations have higher cancer targeting potential.

  18. A single particle effective potential for interacting positron and positronium

    CERN Document Server

    Zubiaga, A; Puska, M

    2013-01-01

    We have studied small systems composed by an atom and a positron or a positronium atom. We have used many-body quantum mechanical calculations to describe the correlation effects of light particles. Explicitly correlated gaussian for the basis functions and a stochastical variational optimization method has allowed to obtain accurate wavefunctions and energies. We have discussed the chemistry of positrons in those systems by means of analyzing the densities of the light particles (electrons and positrons). During the discussion, we propose an effective potential that describes the properties of the positron in those systems, valid also when it forms a Ps cluster. The effective potential is a mean field description of the interaction of the positron that can be used to calculate the distribution of the positron and its interaction energy. This potential can be a step forward for an accurate single particle description of the positron in cases when it forms positronium, specially molecular soft matter.

  19. Effective constraint potential in lattice Weinberg - Salam model

    CERN Document Server

    Polikarpov, M I

    2011-01-01

    We investigate lattice Weinberg - Salam model without fermions for the value of the Weinberg angle $\\theta_W \\sim 30^o$, and bare fine structure constant around $\\alpha \\sim 1/150$. We consider the value of the scalar self coupling corresponding to bare Higgs mass around 150 GeV. The effective constraint potential for the zero momentum scalar field is used in order to investigate phenomena existing in the vicinity of the phase transition between the physical Higgs phase and the unphysical symmetric phase of the lattice model. This is the region of the phase diagram, where the continuum physics is to be approached. We compare the above mentioned effective potential (calculated in selected gauges) with the effective potential for the value of the scalar field at a fixed space - time point. We also calculate the renormalized fine structure constant using the correlator of Polyakov lines and compare it with the one - loop perturbative estimate.

  20. Potentials for food waste minimization and effects on potential biogas production through anaerobic digestion.

    Science.gov (United States)

    Schott, Anna Bernstad Saraiva; Vukicevic, Sanita; Bohn, Irene; Andersson, Tova

    2013-08-01

    Several treatment alternatives for food waste can result in both energy and nutrient recovery, and thereby potential environmental benefits. However, according to the European Union waste management hierarchy, waste prevention should be the prioritized strategy to decrease the environmental burdens from all solid waste management. The aim of the present study was therefore to investigate the potential for food waste minimization among Swedish households through an investigation of the amount of avoidable food waste currently disposed of. A further aim was to investigate the effect on the national biogas production potential through anaerobic digestion of food waste, considering minimization potentials. A method for waste composition analyses of household food waste, where a differentiation between avoidable and unavoidable food waste is made, was used in a total of 24 waste composition analyses of household waste from Swedish residential areas. The total household food waste generation reached 3.4 kg (household and week)(-1), on average, of which 34% is avoidable. The theoretical methane (CH4) potential in unavoidable food waste reached 442 Ndm(3) (kg VS)(-1) or 128 Nm(3) tonne(-1) wet waste, while the measured (mesophilic CH4 batch tests) CH4 production reached 399 Ndm(3) (kg VS)(-1), which is lower than several previous assessments of CH4 production from household food waste. According to this study the combination of a decrease in food waste generation-in case of successful minimization-and decreased CH4 production from unavoidable food waste will thus result in lower total potential energy recovery from household food waste through anaerobic digestion CH4 potential than previously stated.

  1. Exact RG invariance and symmetry improved 2PI effective potential

    Directory of Open Access Journals (Sweden)

    Apostolos Pilaftsis

    2017-07-01

    Full Text Available The Symmetry Improved Two-Particle-Irreducible (SI2PI formalism is a powerful tool to calculate the effective potential beyond perturbation theory, whereby infinite sets of selective loop-graph topologies can be resummed in a systematic and consistent manner. In this paper we study the Renormalization-Group (RG properties of this formalism, by proving for the first time a number of new field-theoretic results. First, the RG runnings of all proper 2PI couplings are found to be UV finite, in the Hartree–Fock and sunset approximations of the 2PI effective action. Second, the SI2PI effective potential is exactly RG invariant, in contrast to what happens in the ordinary One-Particle-Irreducible (1PI perturbation theory, where the effective potential is RG invariant only up to higher orders. Finally, we show how the effective potential of an O(2 theory evaluated in the SI2PI framework, appropriately RG improved, can reach a higher level of accuracy, even up to one order of magnitude, with respect to the corresponding one obtained in the 1PI formalism.

  2. Exact RG invariance and symmetry improved 2PI effective potential

    Science.gov (United States)

    Pilaftsis, Apostolos; Teresi, Daniele

    2017-07-01

    The Symmetry Improved Two-Particle-Irreducible (SI2PI) formalism is a powerful tool to calculate the effective potential beyond perturbation theory, whereby infinite sets of selective loop-graph topologies can be resummed in a systematic and consistent manner. In this paper we study the Renormalization-Group (RG) properties of this formalism, by proving for the first time a number of new field-theoretic results. First, the RG runnings of all proper 2PI couplings are found to be UV finite, in the Hartree-Fock and sunset approximations of the 2PI effective action. Second, the SI2PI effective potential is exactly RG invariant, in contrast to what happens in the ordinary One-Particle-Irreducible (1PI) perturbation theory, where the effective potential is RG invariant only up to higher orders. Finally, we show how the effective potential of an O (2) theory evaluated in the SI2PI framework, appropriately RG improved, can reach a higher level of accuracy, even up to one order of magnitude, with respect to the corresponding one obtained in the 1PI formalism.

  3. Self-Duality Helicity and Higher-Loop Euler-Heisenberg Effective Actions

    Science.gov (United States)

    Dunne, Gerald V.; Schubert, Christian

    2004-10-01

    The Euler-Heisenberg effective action in a self-dual background is remarkably simple at two-loop. This simplicity is due to the inter-relationship between self-duality, helicity and supersymmetry. Applications include two-loop helicity amplitudes, beta-functions and nonperturbative effects. The two-loop Euler-Heisenberg effective Lagrangian for QED in a self-dual background field is naturally expressed in terms of one-loop quantities. This mirrors similar behavior recently found in two-loop amplitudes in N=4 SUSY Yang-Mills theory.

  4. Effective potentials in a bidimensional vibrated granular gas

    Science.gov (United States)

    Velázquez-Pérez, Stephanie; Pérez-Ángel, Gabriel; Nahmad-Molinari, Yuri

    2016-09-01

    We present a numerical study of the spatial correlations of a quasi-two-dimensional granular fluid kept in a nonstatic steady state via vertical shaking. The simulations explore a wide range of vertical accelerations, restitution coefficients, and packing fractions, always staying below the crystallization limit. From the simulations we obtain the relevant pair distribution functions (PDFs), and effective potentials for the interparticle interaction are extracted from these PDFs via the Ornstein-Zernike equation with the Percus-Yevick closure. The correlations in the granular structures originating from these effective potentials are checked against the originating PDF using standard Monte Carlo simulations, and we find in general an excellent agreement. The resulting effective potentials show an increase of the spatial correlation at contact with the decreasing values of the restitution coefficient, and a tendency of the potentials to display deeper wells for more dissipative dynamics. A general exception to this trend appears for a range of values of the forcing, which depends on the restitution coefficient, but not on the density, where resonant bouncing increases correlations, resulting in deeper potential wells. The nature of these resonances is explored and shown to be the result of synchronization in the parabolic flights of the particles.

  5. Potential beneficial effects of butyrate in intestinal and extraintestinal diseases

    Institute of Scientific and Technical Information of China (English)

    Roberto Berni Canani; Margherita Di Costanzo; Ludovica Leone; Monica Pedata; Rosaria Meli; Antonio Calignano

    2011-01-01

    The multiple beneficial effects on human health of the short-chain fatty acid butyrate, synthesized from nonabsorbed carbohydrate by colonic microbiota, are well documented. At the intestinal level, butyrate plays a regulatory role on the transepithelial fluid transport,ameliorates mucosal inflammation and oxidative status,reinforces the epithelial defense barrier, and modulates visceral sensitivity and intestinal motility. In addition,a growing number of studies have stressed the role of butyrate in the prevention and inhibition of colorectal cancer. At the extraintestinal level, butyrate exerts potentially useful effects on many conditions, including hemoglobinopathies, genetic metabolic diseases,hypercholesterolemia, insulin resistance, and ischemic stroke. The mechanisms of action of butyrate are different;many of these are related to its potent regulatory effects on gene expression. These data suggest a wide spectrum of positive effects exerted by butyrate, with a high potential for a therapeutic use in human medicine.

  6. QCD Effective action at high temperature and small chemical potential

    CERN Document Server

    Villavicencio, C

    2007-01-01

    We present a construction of an effective Yang-Mills action for QCD, from the expansion of the fermionic determinant in terms of powers of the chemical potential at high temperature, for the case of massless quarks. We analyze this expansion in the perturbative region and find that it gives extra spurious information. We propose for the non-perturbative sector a simplified effective action which, in principle, contains only the relevant information.

  7. [Classic psychedelic drugs and their potential therapeutic effect].

    Science.gov (United States)

    Bayat, Michael

    2017-09-11

    Over the past decade we have witnessed a renewed scientific interest in the classic hallucinogens (psychedelic drugs). These are substances which exert their effects by an agonist action on the 5-HT2A receptors. The purpose of this paper is to provide a short review and discussion of the psychedelic drugs, their safety profile and their potential antidepressive, anxiolytic and antiaddictive effects. The article primarily focusses on the most recent clinical trials.

  8. Potential effects of environmental regulatory procedures on geothermal development

    Energy Technology Data Exchange (ETDEWEB)

    Beeland, G.V.; Boies, D.B.

    1981-01-01

    The potential effects of several types of applicable environmental regulatory procedures on geothermal development were assessed, and particular problem areas were identified. The possible impact of procedures adopted pursuant to the following Federal statutes were analyzed: Clean Air Act; Clean Water Act; Safe Drinking Water Act; and Resource Conservation and Recovery Act. State regulations applicable, or potentially applicable, to geothermal facilities were also reviewed to determine: permit information requirements; pre-permit air or water quality monitoring requirements; effect of mandated time frames for permit approval; and potential for exemption of small facilities. The regulations of the following states were covered in the review: Alaska; Arizona; California; Colorado; Hawaii; Idaho; Montana; Nevada; New Mexico; Oregon; Utah; Washington; and Wyoming. (MHR)

  9. Potentiators exert distinct effects on human, murine, and Xenopus CFTR.

    Science.gov (United States)

    Cui, Guiying; Khazanov, Netaly; Stauffer, Brandon B; Infield, Daniel T; Imhoff, Barry R; Senderowitz, Hanoch; McCarty, Nael A

    2016-08-01

    VX-770 (Ivacaftor) has been approved for clinical usage in cystic fibrosis patients with several CFTR mutations. Yet the binding site(s) on CFTR for this compound and other small molecule potentiators are unknown. We hypothesize that insight into this question could be gained by comparing the effect of potentiators on CFTR channels from different origins, e.g., human, mouse, and Xenopus (frog). In the present study, we combined this comparative molecular pharmacology approach with that of computer-aided drug discovery to identify and characterize new potentiators of CFTR and to explore possible mechanism of action. Our results demonstrate that 1) VX-770, NPPB, GlyH-101, P1, P2, and P3 all exhibited ortholog-specific behavior in that they potentiated hCFTR, mCFTR, and xCFTR with different efficacies; 2) P1, P2, and P3 potentiated hCFTR in excised macropatches in a manner dependent on the degree of PKA-mediated stimulation; 3) P1 and P2 did not have additive effects, suggesting that these compounds might share binding sites. Also 4) using a pharmacophore modeling approach, we identified three new potentiators (IOWH-032, OSSK-2, and OSSK-3) that have structures similar to GlyH-101 and that also exhibit ortholog-specific potentiation of CFTR. These could potentially serve as lead compounds for development of new drugs for the treatment of cystic fibrosis. The ortholog-specific behavior of these compounds suggest that a comparative pharmacology approach, using cross-ortholog chimeras, may be useful for identification of binding sites on human CFTR.

  10. Examining triclosan-induced potentiation of the estrogen uterotrophic effect

    Science.gov (United States)

    Triclosan (TCS), a widely used antibacterial, has been shown to be an endocrine disruptor. We reported previously that TCS potentiated the estrogenic effect of ethinyl estradiol (EE) on uterine growth in rats orally administered 3 μg/kg EE and TCS (2 to 18 mg/kg) in the utero...

  11. Potential effects of chlorogenic acids on platelet activiation

    Science.gov (United States)

    Coffee (Coffea sp) is a most consumed beverage world-wide. Chlorogenic acids (CHAs) are naturally occurring phenolic acid esters abundantly found in coffee. They are reported to have potential health effects on several chronic diseases such as obesity, diabetes and cardiovascular diseases (CVD). At...

  12. Why are effective potentials 'soft'?

    Energy Technology Data Exchange (ETDEWEB)

    Klapp, Sabine H L; Diestler, Dennis J; Schoen, Martin [Stranski-Laboratorium fuer Physikalische und Theoretische Chemie, Sekretariat TC7, Technische Universitaet Berlin, Strasse des 17 Juni 124, D-10623 Berlin (Germany)

    2004-10-20

    This paper is concerned with effective potentials W{sub 1}(R) between interacting supramolecular particles separated by a distance R. We focus on the question of why these potentials are typically 'soft', i.e., remain finite for R {yields} 0 and vary more weakly with R than the underlying interatomic interaction potentials. On the basis of a general expression linking W{sub 1}(R) to the free energy F of the supramolecular system we investigate the origin of the apparent 'softness' of W{sub 1}(R) by considering a number of special model systems, starting with an atom and a diatomic molecule. This simple model already yields a W{sub 1}(R) that is finite at R = 0, but W{sub 1}(R) does not exhibit the slowly varying character typical of effective potentials for realistic systems. We then show that the larger length scale is recovered when one introduces both many-body interactions and thermal fluctuations within the framework of a 'toy model', that is disc-shaped supramolecular units composed of thermalized configurations of Lennard-Jones atoms. In this case, W{sub 1}(R) varies so slowly that it can be parametrized by estimating the free energy change associated with the overlap of the discs. The resulting overlap approximation to W{sub 1}(R) behaves qualitatively like ad hoc effective potentials used in mesoscale simulations, such as dissipative particle dynamics. Indeed, on the basis of Monte Carlo simulations and a solution of hypernetted chain integral equations, we find that fluids interacting via DPD and overlap potentials have very similar structural and thermophysical properties. Moreover, the 'overlap' fluid (like other 'effective' fluids) turns out to be so 'soft' that its properties, particularly at high densities, can be very well estimated by a mean-field treatment.

  13. Asymptotic Near Nucleus Structure of the Electron-Interaction Potential in Local Effective Potential Theories

    Science.gov (United States)

    Sahni, Viraht; Qian, Zhixin

    2007-03-01

    In previous work, it has been shown that for spherically symmetric or sphericalized systems, the asymptotic near nucleus structure of the electron-interaction potential is vee(r) = vee(0) + βr + γr^2. In this paper we prove via time-independent Quantal Density Functional Theory[1](Q-DFT): (i) correlations due to the Pauli exclusion principle and Coulomb repulsion do not contribute to the linear structure;(ii) these Pauli and Coulomb correlations contribute quadratically; (iii) the linear structure is solely due to Correlation-Kinetic effects, the coefficient β being determined analytically. By application of adiabatic coupling constant perturbation theory via QDFT we further prove: (iv) the Kohn-Sham (KS-DFT) `exchange' potential vx(r) approaches the nucleus linearly, this structure being due solely to lowest- order Correlation-Kinetic effects: (v) the KS-DFT `correlation' potential vc(r) also approaches the nucleus linearly, being solely due to higher-order Correlation-Kinetic contributions. The above conclusions are equally valid for system of arbitrary symmetry, provided spherical averages of the properties are employed. 1 Quantal Density Functional Theory, V. Sahni (Springer-Verlag 2004)

  14. Quantum mechanics of effective potential at a metal surface

    Science.gov (United States)

    Solomatin, Alexander

    In this thesis we study the nonuniform electron density system at a metal-vacuum interface via the corresponding local effective potential confining the electrons, the metal being represented by the jellium and structureless pseudopotential models. The study is performed within conventional Kohn-Sham (KS) density-functional theory and its recently derived quantum-mechanical interpretation. In the latter, properties are determined in terms of the separate electron correlations due to the Pauli exclusion principle, Coulomb repulsion and the correlation contribution to the kinetc energy. We have derived the exact analytical structure, valid for self-consistent orbitals, of the KS theory exchange potential in the classically forbidden region. This structure is image-potential-like of the form -alphasb{KS,x}(beta)chi where the parameter betasp2 is the ratio of the surface barrier height to the metal Fermi energy. For a Wigner-Seitz radius of rsb{s} = 4.1, which is approximately that for which jellium metal is stable, the decay coefficient is precisely 1/4. Over the metallic range of densities rsb{s} = 2-6, the coefficient ranges from 0.195 to 0.274. Thus, if the asymptotic structure of the KS exchange-correlation potential is the image potential, then this structure is due principally to KS exchange effects, the KS correlation contribution being an order of magnitude smaller. These results, then lead to the concept of an 'image' charge localized to the surface region for asymptotic positions of the electron. We have further derived the exact analytical structure in the vacuum of the Slater exchange potential, and of the Pauli-correlation and correlation-kinetic components of the KS exchange potential. These structures are all image-potential-like, decaying respectively as -alphasb{S}(beta)chi,\\ -alphasb{W}(beta)chi and alphasbsp{tsb{c}}{(1)}(beta)/chi. The Pauli-correlation component constitutes the major fraction of the KS exchange potential asymptotically, but there

  15. Effects of auroral potential drops on plasma sheet dynamics

    Science.gov (United States)

    Xi, Sheng; Lotko, William; Zhang, Binzheng; Wiltberger, Michael; Lyon, John

    2016-11-01

    The reaction of the magnetosphere-ionosphere system to dynamic auroral potential drops is investigated using the Lyon-Fedder-Mobarry global model including, for the first time in a global simulation, the dissipative load of field-aligned potential drops in the low-altitude boundary condition. This extra load reduces the field-aligned current (j||) supplied by nightside reconnection dynamos. The system adapts by forcing the nightside X line closer to Earth, with a corresponding reduction in current lensing (j||/B = constant) at the ionosphere and additional contraction of the plasma sheet during substorm recovery and steady magnetospheric convection. For steady and moderate solar wind driving and with constant ionospheric conductance, the cross polar cap potential and hemispheric field-aligned current are lower by approximately the ratio of the peak field-aligned potential drop to the cross polar cap potential (10-15%) when potential drops are included. Hemispheric ionospheric Joule dissipation is less by 8%, while the area-integrated, average work done on the fluid by the reconnecting magnetotail field increases by 50% within |y| < 8 RE. Effects on the nightside plasma sheet include (1) an average X line 4 RE closer to Earth; (2) a 12% higher mean reconnection rate; and (3) dawn-dusk asymmetry in reconnection with a 17% higher rate in the premidnight sector.

  16. Evaluation Of Potential Cytotoxic Effects Of Herbal Extracts

    Directory of Open Access Journals (Sweden)

    Radovanovic Ana

    2015-12-01

    Full Text Available Herbal medicines have played an important role in treating different diseases since ancient times. Bioactive components of medicinal plants are a good starting point for discovering new drugs such as chemotherapeutics. Currently, there are four classes of plant-derived chemotherapeutic drugs used in clinical practice. However, to discover new potential cytotoxic molecules, the research effort on herbal extracts has not diminished. The aim of this review was to evaluate the chemical constituents of plants that possess cytotoxicity, the signalling pathways responsible for this effect, and the influence of solvent polarity on potential cytotoxic effect and to present the cytotoxic activity of selected herbal extracts. The polyphenolic, anthraquinon, diterpneoid, triterpenoid, flavonoid, betulinic acid and berberine content contributes to cytotoxicity of herbal extracts. The inhibitory effect on cancer cells viability could be a consequence of the non-apoptotic processes, such as cell cycle arrestment, and the apoptotic process in tumour cells through different signalling pathways. The influence of solvent polarity on potential cytotoxic effect of herbal extracts should not be ignored. In general, the best cytotoxic activity was found in nonpolar and moderately polar herbal extracts. The herbal extract with IC50 below 30 μg/ml could be considered a very strong cytotoxic agent. Considering that many antitumor drugs have been discovered from natural products, further research on plants and plant-derived chemicals may result in the discovery of potent anticancer agents.

  17. Music listening after stroke: beneficial effects and potential neural mechanisms.

    Science.gov (United States)

    Särkämö, Teppo; Soto, David

    2012-04-01

    Music is an enjoyable leisure activity that also engages many emotional, cognitive, and motor processes in the brain. Here, we will first review previous literature on the emotional and cognitive effects of music listening in healthy persons and various clinical groups. Then we will present findings about the short- and long-term effects of music listening on the recovery of cognitive function in stroke patients and the underlying neural mechanisms of these music effects. First, our results indicate that listening to pleasant music can have a short-term facilitating effect on visual awareness in patients with visual neglect, which is associated with functional coupling between emotional and attentional brain regions. Second, daily music listening can improve auditory and verbal memory, focused attention, and mood as well as induce structural gray matter changes in the early poststroke stage. The psychological and neural mechanisms potentially underlying the rehabilitating effect of music after stroke are discussed. © 2012 New York Academy of Sciences.

  18. Electron interactions in graphene through an effective Coulomb potential

    Science.gov (United States)

    Rodrigues, Joao N. B.; Adam, Shaffique

    A recent numerical work [H.-K. Tang et al, PRL 115, 186602 (2015)] considering graphene's π-electrons interacting through an effective Coulomb potential that is finite at short-distances, stressed the importance of the sp2 -electrons in determining the semimetal to Mott insulator phase transition in graphene. Some years ago, I. F. Herbut [PRL 97, 146401 (2006)] studied such a transition by mapping graphene's π-electrons into a Gross-Neveu model. From a different perspective, D. T. Son [PRB 75, 235423 (2007)] put the emphasis on the long-range interactions by modelling graphene as Dirac fermions interacting through a bare Coulomb potential. Here we build on these works and explore the phase diagram of Dirac fermions interacting through an effective Coulomb-like potential screened at short-distances. The interaction potential used allows for analytic results that controllably switch between the two perspectives above. This work was supported by the Singapore National Research Foundation (NRF-NRFF2012-01 and CA2DM medium-sized centre program) and by the Singapore Ministry of Education and Yale-NUS College (R-607-265-01312).

  19. Effective balance equations for elastic composites subject to inhomogeneous potentials

    Science.gov (United States)

    Penta, Raimondo; Ramírez-Torres, Ariel; Merodio, José; Rodríguez-Ramos, Reinaldo

    2017-08-01

    We derive the new effective governing equations for linear elastic composites subject to a body force that admits a Helmholtz decomposition into inhomogeneous scalar and vector potentials. We assume that the microscale, representing the distance between the inclusions (or fibers) in the composite, and its size (the macroscale) are well separated. We decouple spatial variations and assume microscale periodicity of every field. Microscale variations of the potentials induce a locally unbounded body force. The problem is homogenizable, as the results, obtained via the asymptotic homogenization technique, read as a well-defined linear elastic model for composites subject to a regular effective body force. The latter comprises both macroscale variations of the potentials, and nonstandard contributions which are to be computed solving a well-posed elastic cell problem which is solely driven by microscale variations of the potentials. We compare our approach with an existing model for locally unbounded forces and provide a simplified formulation of the model which serves as a starting point for its numerical implementation. Our formulation is relevant to the study of active composites, such as electrosensitive and magnetosensitive elastomers.

  20. Angle-resolved effective potentials for disk-shaped molecules

    Energy Technology Data Exchange (ETDEWEB)

    Heinemann, Thomas, E-mail: thomas.heinemann@tu-berlin.de; Klapp, Sabine H. L., E-mail: klapp@physik.tu-berlin.de [Institut für Theoretische Physik, Technische Universität Berlin, Hardenbergstr. 36, 10623 Berlin (Germany); Palczynski, Karol, E-mail: karol.palczynski@helmholtz-berlin.de; Dzubiella, Joachim, E-mail: joachim.dzubiella@helmholtz-berlin.de [Institut für Physik, Humboldt Universität zu Berlin, Newtonstraße 15, 12489 Berlin (Germany); Helmholtz Zentrum Berlin (HZB), Institute of Soft Matter and Functional Materials, Hahn-Meitner Platz 1, 14109 Berlin (Germany)

    2014-12-07

    We present an approach for calculating coarse-grained angle-resolved effective pair potentials for uniaxial molecules. For integrating out the intramolecular degrees of freedom we apply umbrella sampling and steered dynamics techniques in atomistically-resolved molecular dynamics (MD) computer simulations. Throughout this study we focus on disk-like molecules such as coronene. To develop the methods we focus on integrating out the van der Waals and intramolecular interactions, while electrostatic charge contributions are neglected. The resulting coarse-grained pair potential reveals a strong temperature and angle dependence. In the next step we fit the numerical data with various Gay-Berne-like potentials to be used in more efficient simulations on larger scales. The quality of the resulting coarse-grained results is evaluated by comparing their pair and many-body structure as well as some thermodynamic quantities self-consistently to the outcome of atomistic MD simulations of many-particle systems. We find that angle-resolved potentials are essential not only to accurately describe crystal structures but also for fluid systems where simple isotropic potentials start to fail already for low to moderate packing fractions. Further, in describing these states it is crucial to take into account the pronounced temperature dependence arising in selected pair configurations due to bending fluctuations.

  1. Angle-resolved effective potentials for disk-shaped molecules.

    Science.gov (United States)

    Heinemann, Thomas; Palczynski, Karol; Dzubiella, Joachim; Klapp, Sabine H L

    2014-12-07

    We present an approach for calculating coarse-grained angle-resolved effective pair potentials for uniaxial molecules. For integrating out the intramolecular degrees of freedom we apply umbrella sampling and steered dynamics techniques in atomistically-resolved molecular dynamics (MD) computer simulations. Throughout this study we focus on disk-like molecules such as coronene. To develop the methods we focus on integrating out the van der Waals and intramolecular interactions, while electrostatic charge contributions are neglected. The resulting coarse-grained pair potential reveals a strong temperature and angle dependence. In the next step we fit the numerical data with various Gay-Berne-like potentials to be used in more efficient simulations on larger scales. The quality of the resulting coarse-grained results is evaluated by comparing their pair and many-body structure as well as some thermodynamic quantities self-consistently to the outcome of atomistic MD simulations of many-particle systems. We find that angle-resolved potentials are essential not only to accurately describe crystal structures but also for fluid systems where simple isotropic potentials start to fail already for low to moderate packing fractions. Further, in describing these states it is crucial to take into account the pronounced temperature dependence arising in selected pair configurations due to bending fluctuations.

  2. Potential neoplastic effects of parathion-methyl on rat liver

    Institute of Scientific and Technical Information of China (English)

    M. Nisa UNALDI CORAL; Sonay UCMAN; Hasan YILDIZ; Haydar OZTAS; Semih DALKILIC

    2009-01-01

    The mutagenic and carcinogenic effects of parathion-methyl were examined by bacterial reverse assay and a long term experiment with Wistar rats. The potential mutagenic effect of parathion-methyl in Salmonella typhimurium TA100 bacterial cells was observed without rat liver S9 metabolic activation. Parathion-methyl was further investigated for pathological changes in rat pancreas and liver. The long-term rat experiments showed that parathion-methyl exposure for 3 months can cause pathological changes in rat pancreases acinar cells and pancreatic hepatocytes. Atypical acinar cell focuses (AACF) were determined in the liver and pancreas of the rats. The results from short-term Ames test and long-term rat experiments suggest that parathion-methyl would be potential carcinogenic.

  3. Quantum effective potential, electron transport and conformons in biopolymers

    Energy Technology Data Exchange (ETDEWEB)

    Dandoloff, Rossen [Laboratoire de Physique Theorique et Modelisation, Universite de Cergy-Pontoise, F-95302 Cergy-Pontoise (France); Balakrishnan, Radha [The Institute of Mathematical Sciences, Chennai 600113 (India)

    2005-07-08

    In the Kirchhoff model of a biopolymer, conformation dynamics can be described in terms of solitary waves, for certain special cross-section asymmetries. Applying this to the problem of electron transport, we show that the quantum effective potential arising due to the bends and twists of the polymer enables us to formalize and quantify the concept of a conformon that has been hypothesized in biology. Its connection to the soliton solution of the cubic nonlinear Schroedinger equation emerges in a natural fashion.

  4. Opinion on potential health effects of exposure to electromagnetic fields.

    Science.gov (United States)

    2015-09-01

    In January 2015, the Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR) published its final opinion on "Potential health effects of exposure to electromagnetic fields." The purpose of this document was to update previous SCENIHR opinions in the light of recently available information since then, and to give special consideration to areas that had not been dealt with in the previous opinions or in which important knowledge gaps had been identified.

  5. EFFECTS OF MANGANESE ON THYROID HORMONE HOMEOSTASIS: POTENTIAL LINKS

    OpenAIRE

    Soldin, OP; Aschner, M.

    2007-01-01

    Manganese (Mn) is an essential trace nutrient that is potentially toxic at high levels of exposure. As a constituent of numerous enzymes and a cofactor, manganese plays an important role in a number of physiologic processes in mammals. The manganese-containing enzyme, manganese superoxide dismutase (Mn-SOD), is the principal antioxidant enzyme which neutralizes the toxic effects of reactive oxygen species. Other manganese-containing enzymes include oxidoreductases, transferases, hydrolases, l...

  6. Effective potential and Goldstone bosons in de Sitter space

    CERN Document Server

    Arai, Takashi

    2013-01-01

    We investigate nonperturbative infrared effects for the O(N) linear sigma model in de Sitter space using the two-particle irreducible effective action at the Hartree truncation level. This approximation resums the infinite series of so-called superdaisy diagrams. For the proper treatment of ultraviolet divergences, we first study the renormalization of this approximation on a general curved background. Then, we calculate radiatively corrected masses and the effective potential. As a result, spontaneous symmetry breaking is possible, on the other hand, the Goldstone modes acquire a positive definite mass term due to the screening effects of interaction. Possible infrared divergence is self-regulated by the mass term. Furthermore, there is a symmetry restoring phase transition as a function of the Hubble parameter. In our approximation, the phase transition is of first order.

  7. Hofmeister effects: interplay of hydration, nonelectrostatic potentials, and ion size.

    Science.gov (United States)

    Parsons, Drew F; Boström, Mathias; Lo Nostro, Pierandrea; Ninham, Barry W

    2011-07-21

    The classical Derjaguin-Landau-Verwey-Overbeek (DLVO) theory of colloids, and corresponding theories of electrolytes, are unable to explain ion specific forces between colloidal particles quantitatively. The same is true generally, for surfactant aggregates, lipids, proteins, for zeta and membrane potentials and in adsorption phenomena. Even with fitting parameters the theory is not predictive. The classical theories of interactions begin with continuum solvent electrostatic (double layer) forces. Extensions to include surface hydration are taken care of with concepts like inner and outer Helmholtz planes, and "dressed" ion sizes. The opposing quantum mechanical attractive forces (variously termed van der Waals, Hamaker, Lifshitz, dispersion, nonelectrostatic forces) are treated separately from electrostatic forces. The ansatz that separates electrostatic and quantum forces can be shown to be thermodynamically inconsistent. Hofmeister or specific ion effects usually show up above ≈10(-2) molar salt. Parameters to accommodate these in terms of hydration and ion size had to be invoked, specific to each case. Ionic dispersion forces, between ions and solvent, for ion-ion and ion-surface interactions are not explicit in classical theories that use "effective" potentials. It can be shown that the missing ionic quantum fluctuation forces have a large role to play in specific ion effects, and in hydration. In a consistent predictive theory they have to be included at the same level as the nonlinear electrostatic forces that form the skeletal framework of standard theory. This poses a challenge. The challenges go further than academic theory and have implications for the interpretation and meaning of concepts like pH, buffers and membrane potentials, and for their experimental interpretation. In this article we overview recent quantitative developments in our evolving understanding of the theoretical origins of specific ion, or Hofmeister effects. These are demonstrated

  8. Thermal grill conditioning: Effect on contact heat evoked potentials

    Science.gov (United States)

    Jutzeler, Catherine R.; Warner, Freda M.; Wanek, Johann; Curt, Armin; Kramer, John L. K.

    2017-01-01

    The ‘thermal grill illusion’ (TGI) is a unique cutaneous sensation of unpleasantness, induced through the application of interlacing warm and cool stimuli. While previous studies have investigated optimal parameters and subject characteristics to evoke the illusion, our aim was to examine the modulating effect as a conditioning stimulus. A total of 28 healthy control individuals underwent three testing sessions on separate days. Briefly, 15 contact heat stimuli were delivered to the right hand dorsum, while the left palmar side of the hand was being conditioned with either neutral (32 °C), cool (20 °C), warm (40 °C), or TGI (20/40 °C). Rating of perception (numeric rating scale: 0–10) and evoked potentials (i.e., N1 and N2P2 potentials) to noxious contact heat stimuli were assessed. While cool and warm conditioning decreased cortical responses to noxious heat, TGI conditioning increased evoked potential amplitude (N1 and N2P2). In line with other modalities of unpleasant conditioning (e.g., sound, visual, and olfactory stimulation), cortical and possibly sub-cortical modulation may underlie the facilitation of contact heat evoked potentials. PMID:28079118

  9. Structural properties of effective potential model by liquid state theories

    Institute of Scientific and Technical Information of China (English)

    Xiang Yuan-Tao; Andrej Jamnik; Yang Kai-Wei

    2010-01-01

    This paper investigates the structural properties of a model fluid dictated by an effective inter-particle oscillatory potential by grand canonical ensemble Monte Carlo (GCEMC) simulation and classical liquid state theories. The chosen oscillatory potential incorporates basic interaction terms used in modeling of various complex fluids which is composed of mesoscopic particles dispersed in a solvent bath, the studied structural properties include radial distribution function in bulk and inhomogeneous density distribution profile due to influence of several external fields. The GCEMC results are employed to test the validity of two recently proposed theoretical approaches in the field of atomic fluids. One is an Ornstein-Zernike integral equation theory approach; the other is a third order + second order perturbation density functional theory. Satisfactory agreement between the GCEMC simulation and the pure theories fully indicates the ready adaptability of the atomic fluid theories to effective model potentials in complex fluids, and classifies the proposed theoretical approaches as convenient tools for the investigation of complex fluids under the single component macro-fluid approximation.

  10. Combining Slater-type orbitals and effective core potentials

    Science.gov (United States)

    Lesiuk, Michał; Tucholska, Aleksandra M.; Moszynski, Robert

    2017-05-01

    We present a general methodology to evaluate matrix elements of the effective core potentials (ECPs) within a one-electron basis set of Slater-type orbitals (STOs). The scheme is based on translation of individual STO distributions in the framework of the Barnett-Coulson method. We discuss different types of integrals which naturally appear and reduce them to a few basic quantities which can be calculated recursively or purely numerically. Additionally, we consider evaluation of the STOs matrix elements involving the core polarization potentials and effective spin-orbit potentials. Construction of the STOs basis sets designed specifically for use with ECPs is discussed and differences in comparison with all-electron basis sets are briefly summarized. We verify the validity of the present approach by calculating excitation energies, static dipole polarizabilities, and valence orbital energies for the alkaline-earth metals (Ca, Sr, and Ba). Finally, we evaluate interaction energies, permanent dipole moments, and ionization energies for barium and strontium hydrides, and compare them with the best available experimental and theoretical data.

  11. The Effects of Calorie Restriction in Depression and Potential Mechanisms

    Science.gov (United States)

    Zhang, Yifan; Liu, Changhong; Zhao, Yinghao; Zhang, Xingyi; Li, Bingjin; Cui, Ranji

    2015-01-01

    Depression, also called major depressive disorder, is a neuropsychiatric disorder jeopardizing an increasing number of the population worldwide. To date, a large number of studies have devoted great attention to this problematic condition and raised several hypotheses of depression. Based on these theories, many antidepressant drugs were developed for the treatment of depression. Yet, the depressed patients are often refractory to the antidepressant therapies. Recently, increasing experimental evidences demonstrated the effects of calorie restriction in neuroendocrine system and in depression. Both basic and clinical investigations indicated that short-term calorie restriction might induce an antidepressant efficacy in depression, providing a novel avenue for treatment. Molecular basis underlying the antidepressant actions of calorie restriction might involve multiple physiological processes, primarily including orexin signaling activation, increased CREB phosphorylation and neurotrophic effects, release of endorphin and ketone production. However, the effects of chronic calorie restriction were quite controversial, in the cases that it often resulted in the long-term detrimental effects via inhibiting the function of 5-HT system and decreasing leptin levels. Here we review such dual effects of calorie restriction in depression and potential molecular basis behind these effects, especially focusing on antidepressant effects. PMID:26412073

  12. Brain potentials associated with the outcome processing in framing effects.

    Science.gov (United States)

    Ma, Qingguo; Feng, Yandong; Xu, Qing; Bian, Jun; Tang, Huixian

    2012-10-24

    Framing effect is a cognitive bias referring to the phenomenon that people respond differently to different but objectively equivalent descriptions of the same problem. By measuring event-related potentials, the present study aimed to investigate the neural mechanisms underlying the framing effect, especially how the negative and positive frames influence the outcome processing in our brain. Participants were presented directly with outcomes framed either positively in terms of lives saved or negatively in terms of lives lost in large and small group conditions, and were asked to rate the favorableness of each of them. The behavioral results showed that the framing effect occurred in both group size conditions, with more favorable evaluations associated with positive framing. Compared with outcomes in positive framing condition, a significant feedback-related negativity (FRN) effect was elicited by outcomes in negative framing condition, even though the outcomes in different conditions were objectively equivalent. The results are explained in terms of the associative model of attribute framing effect which states that attribute framing effect occurs as a result of a valence-based associative processing.

  13. The RG-improved Twin Higgs effective potential at NNLL

    Science.gov (United States)

    Greco, Davide; Mimouni, Kin

    2016-11-01

    We present the Renormalization Group improvement of the Twin Higgs effective potential at cubic order in logarithmic accuracy. We first introduce a model-independent low-energy effective Lagrangian that captures both the pseudo-Nambu-Goldstone boson nature of the Higgs field and the twin light degrees of freedom charged under a copy of the Standard Model. We then apply the background field method to systematically re-sum all the one loop diagrams contributing to the potential. We show how this technique can be efficient to implicitly renormalize the higher-dimensional operators in the twin sector without classifying all of them. A prediction for the Higgs mass in the Twin Higgs model is derived and found to be of the order of M H ˜ 120 GeV with an ultraviolet cut-off m * ˜ 10-20 TeV. Irrespective of any possible ultraviolet completion of the low-energy Lagrangian, the infrared degrees of freedom alone are therefore enough to account for the observed value of the Higgs mass through running effects.

  14. Occurrence and Potential Biological Effects of Amphetamine on Stream Communities.

    Science.gov (United States)

    Lee, Sylvia S; Paspalof, Alexis M; Snow, Daniel D; Richmond, Erinn K; Rosi-Marshall, Emma J; Kelly, John J

    2016-09-06

    The presence of pharmaceuticals, including illicit drugs in aquatic systems, is a topic of environmental significance because of their global occurrence and potential effects on aquatic ecosystems and human health, but few studies have examined the ecological effects of illicit drugs. We conducted a survey of several drug residues, including the potentially illicit drug amphetamine, at 6 stream sites along an urban to rural gradient in Baltimore, Maryland, U.S.A. We detected numerous drugs, including amphetamine (3 to 630 ng L(-1)), in all stream sites. We examined the fate and ecological effects of amphetamine on biofilm, seston, and aquatic insect communities in artificial streams exposed to an environmentally relevant concentration (1 μg L(-1)) of amphetamine. The amphetamine parent compound decreased in the artificial streams from less than 1 μg L(-1) on day 1 to 0.11 μg L(-1) on day 22. In artificial streams treated with amphetamine, there was up to 45% lower biofilm chlorophyll a per ash-free dry mass, 85% lower biofilm gross primary production, 24% greater seston ash-free dry mass, and 30% lower seston community respiration compared to control streams. Exposing streams to amphetamine also changed the composition of bacterial and diatom communities in biofilms at day 21 and increased cumulative dipteran emergence by 65% and 89% during the first and third weeks of the experiment, respectively. This study demonstrates that amphetamine and other biologically active drugs are present in urban streams and have the potential to affect both structure and function of stream communities.

  15. Effective Potential Theory for Diffusion in Binary Ionic Mixtures

    CERN Document Server

    Shaffer, Nathaniel R; Daligault, Jérôme

    2016-01-01

    Self-diffusion and interdiffusion coefficients of binary ionic mixtures are evaluated using the Effective Potential Theory (EPT), and the predictions are compared with the results of molecular dynamics simulations. We find that EPT agrees with molecular dynamics from weak coupling well into the strong coupling regime, which is a similar range of coupling strengths as previously observed in comparisons with the one-component plasma. Within this range, typical relative errors of approximately 20% and worst-case relative errors of approximately 40% are observed. We also examine the Darken model, which approximates the interdiffusion coefficients based on the self-diffusion coefficients.

  16. Virgin coconut oil and its potential cardioprotective effects.

    Science.gov (United States)

    Babu, Abraham Samuel; Veluswamy, Sundar Kumar; Arena, Ross; Guazzi, Marco; Lavie, Carl J

    2014-11-01

    Emphasis on diet to improve the cardiovascular (CV) risk profile has been the focus of many studies. Recently, virgin coconut oil (VCO) has been growing in popularity due to its potential CV benefits. The chemical properties and the manufacturing process of VCO make this oil healthier than its copra-derived counterpart. This review highlights the mechanism through which saturated fatty acids contribute to CV disease (CVD), how oils and fats contribute to the risk of CVD, and the existing views on VCO and how its cardioprotective effects may make this a possible dietary intervention in isolation or in combination with exercise to help reduce the burden of CVDs.

  17. Potential environmental effects of energy conservation measures in northwest industries

    Energy Technology Data Exchange (ETDEWEB)

    Baechler, M C; Gygi, K F; Hendrickson, P L

    1992-01-01

    The Bonneville Power Administration (Bonneville) has identified 101 plants in the Pacific Northwest that account for 80% of the region's industrial electricity consumption. These plants offer a precise target for a conservation program. PNL determined that most of these 101 plants were represented by 11 major industries. We then reviewed 36 major conservation technologies used in these 11 industrial settings to determine their potential environmental impacts. Energy efficiency technologies designed for industrial use may result in direct or indirect environmental impacts. Effects may result from the production of the conservation measure technology, changes in the working environment due to different energy and material requirements, or changes to waste streams. Industry type, work-place conditions, worker training, and environmental conditions inside and outside the plant are all key variables that may affect environmental outcomes. To address these issues this report has three objectives: Describe potential conservation measures that Bonneville may employ in industrial programs and discuss potential primary impacts. Characterize industrial systems and processes where the measure may be employed and describe general environmental issues associated with each industry type. Review environmental permitting, licensing, and other regulatory actions required for industries and summarize the type of information available from these sources for further analysis.

  18. Potentiating Effects of Lactuca sativa on Pentobarbital-Induced Sleep.

    Science.gov (United States)

    Ghorbani, Ahmad; Rakhshandeh, Hassan; Sadeghnia, Hamid Reza

    2013-01-01

    Traditionally, Lactuca sativa (lettuce) has been recommended for its hypnotic property. The present study was planned to investigate sleep-prolonging effect of this plant. The hydro-alcoholic extract (HAE) of lettuce and its water fraction (WF), ethyl acetate fraction (EAF), and n-butanol fraction (NBF) were administrated (IP) to mice 30 min before the pentobarbital injection. Moreover, both in-vivo and in-vitro toxicity of the extracts were determined. The quality of HAE and NBF was also evaluated using HPLC fingerprint. The HAE prolonged the pentobarbital-induced sleep duration at dose of 400 mg/Kg. The NBF was the only fraction which could increase the sleep duration and decrease sleep latency. The effects of NBF were comparable to those of induced by diazepam. The LD50-value for HAE was found to be 4.8 g/Kg. No neurotoxic effect was observed either by HAE or by its fractions in cultured PC12 neuron-like cells. The results suggest that lettuce potentiates pentobarbital hypnosis without major toxic effect. The main component(s) responsible for this effect is most likely to be non-polar agent(s) which found in NBF of this plant.

  19. The Potential Effect of Puerarin in Preventing Atherosclerosis

    Institute of Scientific and Technical Information of China (English)

    朱庆磊; 何爱霞; 韩慧蓉; 吕欣然; 王士雯

    2002-01-01

    Objective:To study the activity of Puerarin (Pue) in scavenging oxygen free radical(OFR) and its inhibitory effect on the oxidative modification of low density lipoprotein (LDL). Methods:Riboflavin-light system was used to generate superoxide anion, and Fenton reaction to generate hydroxylfree radical to study the activity of Pue in scavenging OFR. Hydrogen peroxide-induced hemolysis wasused to study the effect of Pue on erythrocyte hemolysis and malondialdehyde (MDA) production. And ul-traviolet ray and cupric sulfate were used to cause the oxidative modification of LDL for studying the inhib-itory effect of Pue on LDL oxidative modification. Results: (1) Pue could, at concentration of 0.01-1.0mmol/L, scavenge superoxide anion radical and at concentration of 7.5-75μmol/L scavenge hydroxyl rad-ical in a concentration dependent manner. (2) Pue could, at concentration of 0.1-10 mmol/L, inhibit sig-nificantly oxidative hemolysis and MDA production of erythrocyte induced by hydrogen peroxide. (3) Pueof 0.01-1.0 mmol/L could inhibit the oxidative modification of LDL in a concentration dependent man-ner. Conclusion: Pue has an anti-peroxidation effect and shows a potential effect in preventing atherosclero-sis.

  20. Baroreceptor activation attenuates attentional effects on pain-evoked potentials.

    Science.gov (United States)

    Gray, Marcus A; Minati, Ludovico; Paoletti, Giulia; Critchley, Hugo D

    2010-12-01

    Focused attention typically enhances neural nociceptive responses, reflected electroencephalographically as increased amplitude of pain-evoked event-related potentials (ERPs). Additionally, pain-evoked ERPs are attenuated by hypertension and baroreceptor activity, through as yet unclear mechanisms. There is indirect evidence that these two effects may interact, suggesting that baroreceptor-related modulation of nociception is more than a low-level gating phenomenon. To address this hypothesis, we explored in a group of healthy participants the combined effects of cue-induced expectancy and baroreceptor activity on the amplitude of pain-evoked ERPs. Brief nociceptive skin stimuli were delivered during a simple visual task; half were preceded by a visual forewarning cue, and half were unpredictable. Nociceptive stimuli were timed to coincide either with systole (maximum activation of cardiac baroreceptors) or with diastole (minimum baroreceptor activation). We observed a strong interaction between expectancy and cardiac timing for the amplitude of the P2 ERP component; no effects were observed for the N2 component. Cued stimuli were associated with larger P2 amplitude, but this effect was abolished for stimuli presented during baroreceptor activation. No cardiac timing effect was observed for un-cued stimuli. Taken together, these findings suggest a close integration of cognitive-affective aspects of expectancy and baroreceptor influences on pain, and as such may cast further light on mechanisms underlying mental and physiological contributions to clinical pain.

  1. Lithium effects: protection against nitrogen narcosis, potentiation of HPNS.

    Science.gov (United States)

    Bennett, P B; Leventhal, B L; Coggin, R; Roby, J; Racanska, L

    1980-03-01

    The effect of either 10, 8, or 6 meq/kg of intraperitoneal lithium chloride or sodium chloride on the loss of righting response (RR50) produced by 18.2 ATA N2-ATA O2 was examined in rats. Results were compared to the effects of 10, 8, 6, or 4 meq/kg of intraperitoneal lithium chloride given 24 h before determination of the convulsion pressure (PC) in 40 rats compressed with He-O2 at 160 atm/h at 37 +/- 0.5 degrees C. Lithium (10 meq/kg) prevented the nitrogen-narcosis-induced loss of righting response but significantly potentiated the pressure (depth) at which convulsions and tremors occurred.

  2. The RG-improved Twin Higgs effective potential at NNLL

    CERN Document Server

    Greco, Davide

    2016-01-01

    We present the Renormalization Group improvement of the Twin Higgs effective potential at cubic order in logarithmic accuracy. We first introduce a model-independent low-energy effective Lagrangian that captures both the pseudo-Nambu-Goldstone boson nature of the Higgs field and the twin light degrees of freedom charged under a copy of the Standard Model. We then apply the background field method to systematically re-sum all the one loop diagrams contributing to the potential. We show how this technique can be efficient to implicitly renormalize the higher-dimensional operators in the twin sector without classifying all of them. A prediction for the Higgs mass in the Twin Higgs model is derived and found to be of the order of $M_H \\sim 120 ~\\text{GeV}$ with an ultraviolet cut-off $m_*\\sim 10-20 ~\\text{TeV}$. Irrespective of any possible ultraviolet completion of the low-energy Lagrangian, the infrared degrees of freedom alone are therefore enough to account for the observed value of the Higgs mass through run...

  3. Effects of metformin on weight loss: potential mechanisms.

    Science.gov (United States)

    Malin, Steven K; Kashyap, Sangeeta R

    2014-10-01

    Despite the known glucose-lowering effects of metformin, more recent clinical interest lies in its potential as a weight loss drug. Herein, we discuss the potential mechanisms by which metformin decreases appetite and opposes unfavorable fat storage in peripheral tissues. Many individuals struggle to maintain clinically relevant weight loss from lifestyle and bariatric surgery interventions. Long-term follow-up from the Diabetes Prevention Program demonstrates that metformin produces durable weight loss, and decreased food intake by metformin is the primary weight loss mechanism. Although the effect of metformin on appetite is likely to be multifactorial, changes in hypothalamic physiology, including leptin and insulin sensitivity, have been documented. In addition, novel work in obesity highlights the gastrointestinal physiology and circadian rhythm changes by metformin as not only affecting food intake, but also the regulation of fat oxidation and storage in liver, skeletal muscle, and adipose tissue. Metformin induces modest weight loss in overweight and obese individuals at risk for diabetes. A more detailed understanding of how metformin induces weight loss will likely lead to optimal co-prescription of lifestyle modification with pharmacology for the treatment of obesity independent of diabetes.

  4. Abuse potential and adverse cognitive effects of mitragynine (kratom).

    Science.gov (United States)

    Yusoff, Nurul H M; Suhaimi, Farah W; Vadivelu, Raja K; Hassan, Zurina; Rümler, Anne; Rotter, Andrea; Amato, Davide; Dringenberg, Hans C; Mansor, Sharif M; Navaratnam, Visweswaran; Müller, Christian P

    2016-01-01

    Mitragynine is the major psychoactive alkaloid of the plant kratom/ketum. Kratom is widely used in Southeast Asia as a recreational drug, and increasingly appears as a pure compound or a component of 'herbal high' preparations in the Western world. While mitragynine/kratom may have analgesic, muscle relaxant and anti-inflammatory effects, its addictive properties and effects on cognitive performance are unknown. We isolated mitragynine from the plant and performed a thorough investigation of its behavioural effects in rats and mice. Here we describe an addictive profile and cognitive impairments of acute and chronic mitragynine administration, which closely resembles that of morphine. Acute mitragynine has complex effects on locomotor activity. Repeated administration induces locomotor sensitization, anxiolysis and conditioned place preference, enhances expression of dopamine transporter- and dopamine receptor-regulating factor mRNA in the mesencephalon. While there was no increase in spontaneous locomotor activity during withdrawal, animals showed hypersensitivity towards small challenging doses for up to 14 days. Severe somatic withdrawal signs developed after 12 hours, and increased level of anxiety became evident after 24 hours of withdrawal. Acute mitragynine independently impaired passive avoidance learning, memory consolidation and retrieval, possibly mediated by a disruption of cortical oscillatory activity, including the suppression of low-frequency rhythms (delta and theta) in the electrocorticogram. Chronic mitragynine administration led to impaired passive avoidance and object recognition learning. Altogether, these findings provide evidence for an addiction potential with cognitive impairments for mitragynine, which suggest its classification as a harmful drug.

  5. Potential Climate Effects of Dust Aerosols' over West Africa

    Science.gov (United States)

    JI, Z.; Wang, G.; Pal, J. S.; Yu, M.

    2014-12-01

    Climate in West Africa is under the influence of the West African monsoon circulation and mineral dust emitted from the Sahara desert (which is the world's largest source of mineral dust emission). Dust aerosols alter the atmospheric radiative fluxes and act as cloud condensation nuclei in the process of emission, transportation and deposition. However, our understanding regarding how dust aerosols influence the present-day and future climate of West Africa is very limited. In this study, a regional climate model RegCM4.3.4-CLM4.5 is used to investigate the potential climatic effects of dust aerosols both in present (1981-2000) and future (2081-2100) periods over WA. First, the model performance and dust climatic effects are evaluated. The contribution of dust climatic effects under RCP8.5 scenario and their confounding effects with land use change are assessed. Our results indicate that the model can reproduce with reasonable accuracy the spatial and temporal distribution of climatology, aerosol optical depth and surface concentration over WA. The shortwave radiative forcing of dust is negative in the surface and positive in the atmosphere, with greater changes in JJA and MAM compared to those in SON and DJF. Over most of West Africa, cooling is the dominant effect on temperature. Their impact on precipitation features a dipole pattern, with decrease in the north and increase in the south of West Africa. Despite the dust-induced decrease of precipitation amount, dusts cause extreme precipitation to increase. To evaluate the uncertainties surrounding our modeling results, sensitivity experiments driven by ICBC from MIROC-ESM and CESM and their dynamic downscaling results are used for comparisons. Results from these sensitivity experiments indicate that the impact of dust aerosols on present and future climate is robust.

  6. Potential ergogenic effects of arginine and creatine supplementation.

    Science.gov (United States)

    Paddon-Jones, Douglas; Børsheim, Elisabet; Wolfe, Robert R

    2004-10-01

    The rationale for the use of nutritional supplements to enhance exercise capacity is based on the assumption that they will confer an ergogenic effect above and beyond that afforded by regular food ingestion alone. The proposed or advertised ergogenic effect of many supplements is based on a presumptive metabolic pathway and may not necessarily translate to quantifiable changes in a variable as broadly defined as exercise performance. L-arginine is a conditionally essential amino acid that has received considerable attention due to potential effects on growth hormone secretion and nitric oxide production. In some clinical circumstances (e.g., burn injury, sepsis) in which the demand for arginine cannot be fully met by de novo synthesis and normal dietary intake, exogenous arginine has been shown to facilitate the maintenance of lean body mass and functional capacity. However, the evidence that supplemental arginine may also confer an ergogenic effect in normal healthy individuals is less compelling. In contrast to arginine, numerous studies have reported that supplementation with the arginine metabolite creatine facilitates an increase in anaerobic work capacity and muscle mass when accompanied by resistance training programs in both normal and patient populations. Whereas improvement in the rate of phosphocreatine resynthesis is largely responsible for improvements in acute work capacity, the direct effect of creatine supplementation on skeletal muscle protein synthesis is less clear. The purpose of this review is to summarize the role of arginine and its metabolite creatine in the context of a nutrition supplement for use in conjunction with an exercise stimulus in both healthy and patient populations.

  7. Potential biological and ecological effects of flickering artificial light.

    Directory of Open Access Journals (Sweden)

    Richard Inger

    Full Text Available Organisms have evolved under stable natural lighting regimes, employing cues from these to govern key ecological processes. However, the extent and density of artificial lighting within the environment has increased recently, causing widespread alteration of these regimes. Indeed, night-time electric lighting is known significantly to disrupt phenology, behaviour, and reproductive success, and thence community composition and ecosystem functioning. Until now, most attention has focussed on effects of the occurrence, timing, and spectral composition of artificial lighting. Little considered is that many types of lamp do not produce a constant stream of light but a series of pulses. This flickering light has been shown to have detrimental effects in humans and other species. Whether a species is likely to be affected will largely be determined by its visual temporal resolution, measured as the critical fusion frequency. That is the frequency at which a series of light pulses are perceived as a constant stream. Here we use the largest collation to date of critical fusion frequencies, across a broad range of taxa, to demonstrate that a significant proportion of species can detect such flicker in widely used lamps. Flickering artificial light thus has marked potential to produce ecological effects that have not previously been considered.

  8. One-loop potential with scale invariance and effective operators

    CERN Document Server

    Ghilencea, D M

    2016-01-01

    We study quantum corrections to the scalar potential in classically scale invariant theories, using a manifestly scale invariant regularization. To this purpose, the subtraction scale $\\mu$ of the dimensional regularization is generated after spontaneous scale symmetry breaking, from a subtraction function of the fields, $\\mu(\\phi,\\sigma)$. This function is then uniquely determined from general principles showing that it depends on the dilaton only, with $\\mu(\\sigma)\\sim \\sigma$. The result is a scale invariant one-loop potential $U$ for a higgs field $\\phi$ and dilaton $\\sigma$ that contains an additional {\\it finite} quantum correction $\\Delta U(\\phi,\\sigma)$, beyond the Coleman Weinberg term. $\\Delta U$ contains new, non-polynomial effective operators like $\\phi^6/\\sigma^2$ whose quantum origin is explained. A flat direction is maintained at the quantum level, the model has vanishing vacuum energy and the one-loop correction to the mass of $\\phi$ remains small without tuning (of its self-coupling, etc) bey...

  9. Effective potential for moment-method simulation of quantum devices

    Science.gov (United States)

    Kriman, A. M.; Zhou, J.-R.; Kluksdahl, N. C.; Choi, H. H.; Ferry, D. K.

    1989-12-01

    In the simulation of submicron devices, complete quantum descriptions can be extremely computationally intensive, and reduced descriptions are desirable. One such description utilizes a few low-order moments of the momentum distribution that are defined by the Wigner function. Two major difficulties occur in applying this moment method: (i) An independent calculation is required to find quantum mechanically accurate initial conditions. (ii) For a system in a mixed state, the hierarchy of time evolution equations for the moments does not close. We describe an approach to solve these problems. The initial distribution is determined in equilibrium by means of a new effective potential, chosen for its ability to treat the sharp potential features which occur in heterostructures. It accurately describes barrier penetration and repulsion, as well as quantum broadening of the momentum distribution. The moment equation hierarchy is closed at the level of the second-moment time evolution equation, using a closure that is exact for a shifted Fermi distribution. Band-bending is included by simultaneous self-consistent determination of all the moments.

  10. Estimation of Potential Population Level Effects of Contaminants on Wildlife

    Energy Technology Data Exchange (ETDEWEB)

    Loar, J.M.

    2001-06-11

    The objective of this project is to provide DOE with improved methods to assess risks from contaminants to wildlife populations. The current approach for wildlife risk assessment consists of comparison of contaminant exposure estimates for individual animals to literature-derived toxicity test endpoints. These test endpoints are assumed to estimate thresholds for population-level effects. Moreover, species sensitivities to contaminants is one of several criteria to be considered when selecting assessment endpoints (EPA 1997 and 1998), yet data on the sensitivities of many birds and mammals are lacking. The uncertainties associated with this approach are considerable. First, because toxicity data are not available for most potential wildlife endpoint species, extrapolation of toxicity data from test species to the species of interest is required. There is no consensus on the most appropriate extrapolation method. Second, toxicity data are represented as statistical measures (e.g., NOAEL s or LOAELs) that provide no information on the nature or magnitude of effects. The level of effect is an artifact of the replication and dosing regime employed, and does not indicate how effects might increase with increasing exposure. Consequently, slight exceedance of a LOAEL is not distinguished from greatly exceeding it. Third, the relationship of toxic effects on individuals to effects on populations is poorly estimated by existing methods. It is assumed that if the exposure of individuals exceeds levels associated with impaired reproduction, then population level effects are likely. Uncertainty associated with this assumption is large because depending on the reproductive strategy of a given species, comparable levels of reproductive impairment may result in dramatically different population-level responses. This project included several tasks to address these problems: (1) investigation of the validity of the current allometric scaling approach for interspecies extrapolation

  11. An effective quintessence field with a power-law potential

    CERN Document Server

    Khurshudyan, M; Myrzakulov, R; Chattopadhyay, S; Kahya, E O

    2014-01-01

    In this paper, we will consider an effective quintessence scalar field with a power-law potential interacting with a $P_{b}=\\xi q\\rho_{b}$ barotropic fluid as a first model, where $q$ is a deceleration parameter. For the second model we assume viscous polytropic gas interacting with the scalar field. We investigate problem numerically and analyze behavior of different cosmological parameter concerning to components and behavior of Universe. We also compare our results with observational data to fix parameters of the models. We find some instabilities in the first model which may disappear in the second model for the appropriate parameters. Therefore, we can propose interacting quintessence dark energy with viscous polytropic gas as a successful model to describe Universe.

  12. Effective potential kinetic theory for strongly coupled plasmas

    Science.gov (United States)

    Baalrud, Scott D.; Daligault, Jérôme

    2016-11-01

    The effective potential theory (EPT) is a recently proposed method for extending traditional plasma kinetic and transport theory into the strongly coupled regime. Validation from experiments and molecular dynamics simulations have shown it to be accurate up to the onset of liquid-like correlation parameters (corresponding to Γ ≃ 10-50 for the one-component plasma, depending on the process of interest). Here, this theory is briefly reviewed along with comparisons between the theory and molecular dynamics simulations for self-diffusivity and viscosity of the one-component plasma. A number of new results are also provided, including calculations of friction coefficients, energy exchange rates, stopping power, and mobility. The theory is also cast in the Landau and Fokker-Planck kinetic forms, which may prove useful for enabling efficient kinetic computations.

  13. Effective Potential and Interdiffusion in Binary Ionic Mixtures

    CERN Document Server

    Beznogov, M V

    2014-01-01

    We calculate interdiffusion coefficients in a two-component, weakly or strongly coupled ion plasma (gas or liquid, composed of two ion species immersed into a neutralizing electron background). We use an effective potential method proposed recently by Baalrud and Daligaut [PRL, 110, 235001, (2013)]. It allows us to extend the standard Chapman-Enskog procedure of calculating the interdiffusion coefficients to the case of strong Coulomb coupling. We compute binary diffusion coefficients for several ionic mixtures and fit them by convenient expressions in terms of the generalized Coulomb logarithm. These fits cover a wide range of plasma parameters spanning from weak to strong Coulomb couplings. They can be used to simulate diffusion of ions in ordinary stars as well as in white dwarfs and neutron stars.

  14. A note on two-loop superloop

    CERN Document Server

    Belitsky, A V

    2012-01-01

    We explore the duality between supersymmetric Wilson loop on null polygonal contours in maximally supersymmetric Yang-Mills theory and next-to-maximal helicity violating (NMHV) scattering amplitudes. Earlier analyses demonstrated that the use of a dimensional regulator for ultraviolet divergences, induced due to presence of the cusps on the loop, yields anomalies that break both conformal symmetry and supersymmetry. At one-loop order, these are present only in Grassmann components localized in the vicinity of a single cusp and result in a universal function for any number of sites of the polygon that can be subtracted away in a systematic manner leaving a well-defined supersymmetric remainder dual to corresponding components of the superamplitude. The question remains though whether components which were free from the aforementioned supersymmetric anomaly at leading order of perturbation theory remain so once computed at higher orders. Presently we verify this fact by calculating a particular component of the...

  15. Potential retention effect at fish farms boosts zooplankton abundance

    Science.gov (United States)

    Fernandez-Jover, D.; Toledo-Guedes, K.; Valero-Rodríguez, J. M.; Fernandez-Gonzalez, V.; Sanchez-Jerez, P.

    2016-11-01

    Coastal aquaculture activities influence wild macrofauna in natural environments due to the introduction of artificial structures, such as floating cages, that provide structural complexity in the pelagic system. This alters the abundance and distribution of the affected species and also their feeding behaviour and diet. Despite this, the effects of coastal aquaculture on zooplankton assemblages and the potential changes in their abundance and distribution remain largely unstudied. Traditional plankton sampling hauls between the farm mooring systems entail some practical difficulties. As an alternative, light traps were deployed at 2 farms in the SW Mediterranean during a whole warm season. Total zooplankton capture by traps at farms was higher than at control locations on every sampling night. It ranged from 3 to 10 times higher for the taxonomic groups: bivalvia, cladocera, cumacea, fish early-life-stages, gastropoda, polychaeta and tanaidacea; 10-20 times higher for amphipoda, chaetognatha, isopoda, mysidacea and ostracoda, and 22 times higher for copepoda and the crustacean juvenile stages zoea and megalopa. Permutational analysis showed significant differences for the most abundant zooplankton groups (copepoda, crustacean larvae, chaetognatha, cladocera, mysidacea and polychaeta). This marked incremental increase in zooplankton taxa at farms was consistent, irrespective of the changing environmental variables registered every night. Reasons for the greater abundance of zooplankton at farms are discussed, although results suggest a retention effect caused by cage structures rather than active attraction through physical or chemical cues.

  16. Effect of stimulus check size on multifocal visual evoked potentials.

    Science.gov (United States)

    Balachandran, Chandra; Klistorner, Alexander I; Graham, Stuart L

    2003-03-01

    In this study we examined the effects of varying stimulus check size on multifocal visual evoked potential (VEP). We also evaluated the currently used cortical scaling of stimulus segments. The ObjectiVision multifocal objective perimeter stimulates the eye with random check patterns at 56 cortically scaled segments within the visual field extending to a radius of 26 degrees. All cortically scaled segments have equal number of checks, which gradually increase in size from the center to the periphery, proportional to the size of the segment. Stimuli with 9, 16, 25, 36 and 49 checks/segment were tested on 10 eyes belonging to 10 normal subjects. The check size varied inversely with number of checks per segment. VEP was recorded using bipolar occipital cross electrodes (7 min/eye), the amplitude and latency of responses obtained were compared with the check size at different eccentricities. Our findings suggest that the existing setting with 16 checks/segment subtending 26' to 140' from center to periphery, is the most effective amongst all the check sizes. Decreasing the check size prolongs the latency in the central field only. Cortical scaling of segments generates responses of the same order of magnitude throughout the field, but could be improved slightly to enhance the signal from the outer two rings.

  17. Investigations on potential co-mutagenic effects of formaldehyde.

    Science.gov (United States)

    Speit, Günter; Linsenmeyer, Regina; Duong, Giang; Bausinger, Julia

    2014-02-01

    The genotoxicity and mutagenicity of formaldehyde (FA) has been well-characterized during the last years. Besides its known direct DNA-damaging and mutagenic activity in sufficiently exposed cells, FA at low concentrations might also enhance the mutagenic and carcinogenic effects of other environmental mutagens by interfering with the repair of DNA lesions induced by these mutagens. To further assess potential co-mutagenic effects of FA, we exposed A549 human lung cells to FA in combination with various mutagens and measured the induction and removal of DNA damage by the comet assay and the production of chromosomal mutations by the cytokinesis-block micronucleus assay (CBMN assay). The mutagens tested were ionizing radiation (IR), (±)-anti-B[a]P-7,8-dihydrodiol-9,10-epoxide (BPDE), N-nitroso-N-methylurea (methyl nitrosourea; MNU) and methyl methanesulfonate (MMS). FA (10-75μM) did not enhance the genotoxic and mutagenic activity of these mutagens under the test conditions applied. FA alone and in combination with MNU or MMS did not affect the expression (mRNA level) of the gene of the O(6)-methylguanine-DNA methyltransferase (MGMT) in A549 cells. The results of these experiments do not support the assumption that low FA concentrations might interfere with the repair of DNA damage induced by other mutagens.

  18. Potential of carbon nanotube field effect transistors for analogue circuits

    KAUST Repository

    Hayat, Khizar

    2013-05-11

    This Letter presents a detailed comparison of carbon nanotube field effect transistors (CNFETs) and metal oxide semiconductor field effect transistors (MOSFETs) with special focus on carbon nanotube FET\\'s potential for implementing analogue circuits in the mm-wave and sub-terahertz range. The latest CNFET lithographic dimensions place it at-par with complementary metal oxide semiconductor in terms of current handling capability, whereas the forecasted improvement in the lithography enables the CNFETs to handle more than twice the current of MOSFETs. The comparison of RF parameters shows superior performance of CNFETs with a g m , f T and f max of 2.7, 2.6 and 4.5 times higher, respectively. MOSFET- and CNFET-based inverter, three-stage ring oscillator and LC oscillator have been designed and compared as well. The CNFET-based inverters are found to be ten times faster, the ring oscillator demonstrates three times higher oscillation frequency and CNFET-based LC oscillator also shows improved performance than its MOSFET counterpart.

  19. Potential energetic effects of mountain climbers on foraging grizzly bears

    Science.gov (United States)

    White, D.; Kendall, K.C.; Picton, H.D.

    1999-01-01

    Most studies of the effects of human disturbance on grizzly bears (Ursus arctos horribilis) have not quantified the energetic effects of such interactions. In this study, we characterized activity budgets of adult grizzly bears as they foraged on aggregations of adult army cutworm moths (Euxoa auxiliaris) in the alpine of Glacier National Park, Montana, during 1992, 1994, and 1995. We compared the activity budgets of climber-disturbed bears to those of undisturbed bears to estimate the energetic impact of climber disturbance. When bears detected climbers, they subsequently spent 53% less time foraging on moths, 52% more time moving within the foraging area, and 23% more time behaving aggressively, compared to when they were not disturbed. We estimated that grizzly bears could consume approximately 40,000 moths/day or 1,700 moths/hour. At 0.44 kcal/moth, disruption of moth feeding cost bears approximately 12 kcal/minute in addition to the energy expended in evasive maneuvers and defensive behaviors. To reduce both climber interruption of bear foraging and the potential for aggressive bear-human encounters, we recommend routing climbers around moth sites used by bears or limiting access to these sites during bear-use periods.

  20. Harmonic expansion of the effective potential in a functional renormalization group at finite chemical potential

    Science.gov (United States)

    Barnaföldi, G. G.; Jakovác, A.; Pósfay, P.

    2017-01-01

    In this paper we propose a method to study the functional renormalization group (FRG) at finite chemical potential. The method consists of mapping the FRG equations within the Fermi surface into a differential equation defined on a rectangle with zero boundary conditions. To solve this equation we use an expansion of the potential in a harmonic basis. With this method we determined the phase diagram of a simple Yukawa-type model; as expected, the bosonic fluctuations decrease the strength of the transition.

  1. Potential Health Effects of Enzymatic Protein Hydrolysates from Chlorella vulgaris

    Directory of Open Access Journals (Sweden)

    Mahsa Sedighi

    2016-06-01

    Full Text Available Background and Objective: Chlorella vulgaris is a multi-cellular edible algal species with abundant proteins. Extraction of high value protein fractions for pharmaceutical and nutritional applications can significantly increase the commercial value of microalga biomasses. There is no known report on the anticancer peptides derived from the Chlorella vulgaris abundant protein.Materials and Methods: This study examined the antimicrobial and anticancer effects of peptides from a hydrolyzed Chlorella vulgaris protein with 62 kDa molecular weight. Protein hydrolysis was done by pepsin as a gastrointestinal protease, and was monitored through protein content measurement, sodium dodecyl sulfate polyacrylamide gel electrophoresis, and high performance liquidchromatography measurements. Inhibitory effect of the produced peptides on Escherichia coli cells and breast cancer cell lines was assayed.Results and Conclusion: Hydrolyzed peptides induced a decrease of about 34.1% in the growth of Escherichia coli, and the peptides of 3 to 5 kDa molecular weight had strong impact on the viability of breast cancer cells with IC50 value of 50 μg μl-1. The peptide fractions demonstrating antimicrobial and anti-cancer activities have the potential for use as functional food ingredients for health benefits. These results demonstrate that inexpensive algae proteinscould be a new alternative to produce anticancer peptides.Conflict of interest: The authors declare that there is no conflict of interest.

  2. Age and gender effects on submental motor-evoked potentials.

    Science.gov (United States)

    Sella, Oshrat; Jones, Richard D; Huckabee, Maggie-Lee

    2014-01-01

    It is not known whether there are age- and/or gender-related differences in magnitude of motor-evoked potentials (MEPs) of the submental muscles. Knowledge of this is important in investigations of neurophysiological aspects of swallowing. Forty healthy participants (20 males, 20 females; 20 young [21-35 years], 20 old [53-88 years]) were recruited. Surface electromyography (EMG) electrodes were placed at midline underlying the submental muscle group. Age- and gender-related differences were evaluated in two neurophysiologic measures of swallowing: MEPs stimulated by single-pulse transcranial magnetic stimulation (TMS) over the motor cortex and surface electromyography (sEMG) recorded from the same submental muscle group during non-stimulated swallows. The older participants had larger MEPs during saliva swallowing than the young participants (p = 0.04, d = 0.86). Conversely, the older participants had lower amplitude submental EMG activity during non-stimulated swallows (p = 0.045, d = 0.67). Gender had no significant effect on MEP magnitude and on submental activity during saliva swallowing. There were no effects of age or gender on MEP latencies. These findings suggest deterioration in muscle function with age in a sample of healthy adults presenting with functional swallowing. We speculate that muscular decline is partially ameliorated by increased cortical activity-i.e., increased submental MEPs-so as to preserve swallowing function in healthy older subjects. These findings emphasize the need for different reference points for evaluation of submental MEPs of different age groups.

  3. Investigations on potential co-mutagenic effects of formaldehyde

    Energy Technology Data Exchange (ETDEWEB)

    Speit, Günter, E-mail: guenter.speit@uni-ulm.de; Linsenmeyer, Regina; Duong, Giang; Bausinger, Julia

    2014-02-15

    Highlights: • A549 cells were exposed to formaldehyde in combination with various mutagens. • Formaldehyde did not affect the induction and removal of DNA damage (comet assay). • Formaldehyde did not affect the induction of micronuclei by the mutagens tested. • The expression of the O{sup 6}-methylguanine-DNA methyltransferase was not affected. - Abstract: The genotoxicity and mutagenicity of formaldehyde (FA) has been well-characterized during the last years. Besides its known direct DNA-damaging and mutagenic activity in sufficiently exposed cells, FA at low concentrations might also enhance the mutagenic and carcinogenic effects of other environmental mutagens by interfering with the repair of DNA lesions induced by these mutagens. To further assess potential co-mutagenic effects of FA, we exposed A549 human lung cells to FA in combination with various mutagens and measured the induction and removal of DNA damage by the comet assay and the production of chromosomal mutations by the cytokinesis-block micronucleus assay (CBMN assay). The mutagens tested were ionizing radiation (IR), (±)-anti-B[a]P-7,8-dihydrodiol-9,10-epoxide (BPDE), N-nitroso-N-methylurea (methyl nitrosourea; MNU) and methyl methanesulfonate (MMS). FA (10–75 μM) did not enhance the genotoxic and mutagenic activity of these mutagens under the test conditions applied. FA alone and in combination with MNU or MMS did not affect the expression (mRNA level) of the gene of the O{sup 6}-methylguanine-DNA methyltransferase (MGMT) in A549 cells. The results of these experiments do not support the assumption that low FA concentrations might interfere with the repair of DNA damage induced by other mutagens.

  4. Interactions among endophytic bacteria and fungi: effects and potentials

    Indian Academy of Sciences (India)

    W M M S Bandara; Gamini Seneviratne; S A Kulasooriya

    2006-12-01

    Plants benefit extensively by harbouring endophytic microbes. They promote plant growth and confer enhanced resistance to various pathogens. However, the way the interactions among endophytes influence the plant productivity has not been explained. Present study experimentally showed that endophytes isolated from rice (Oryza sativa) used as the test plant produced two types of interactions; biofilms (bacteria attached to mycelia) and mixed cultures with no such attachments. Acidity, as measured by pH in cultures with biofilms was higher than that of fungi alone, bacteria alone or the mixed cultures. Production of indoleacetic acid like substances (IAAS) of biofilms was higher than that of mixed cultures, fungi or bacteria. Bacteria and fungi produced higher quantities of IAAS than mixed cultures. In mixed cultures, the potential of IAAS production of resident microbes was reduced considerably. There was a negative relationship between IAAS and pH of the biofilms, indicating that IAAS was the main contributor to the acidity. However, such a relationship was not observed in mixed cultures. Microbial acid production is important for suppressing plant pathogens. Thus the biofilm formation in endophytic environment seems to be very important for healthy and improved plant growth. However, it is unlikely that an interaction among endophytes takes place naturally in the endophytic environment, due to physical barriers of plant tissues. Further, critical cell density dependant quorum sensing that leads to biofilm formation may not occur in the endophytic environment as there is a limited space. As such in vitro production and application of beneficial biofilmed inocula of endophytes are important for improved plant production in any agro-ecosystem. The conventional practice of plant inoculation with monocultures or mixed cultures of effective microbes may not give the highest microbial effect, which may only be achieved by biofilm formation.

  5. [Effect of sleep deprivation on visual evoked potentials and brain stem auditory evoked potentials in epileptics].

    Science.gov (United States)

    Urumova, L T; Kovalenko, G A; Tsunikov, A I; Sumskiĭ, L I

    1984-01-01

    The article reports on the first study of the evoked activity of the brain in epileptic patients (n = 20) following sleep deprivation. An analysis of the data obtained has revealed a tendency to the shortening of the peak latent intervals of visual evoked potentials in the range of 100-200 mu sec and the V component and the interpeak interval III-V of evoked auditory trunk potentials in patients with temporal epilepsy. The phenomenon may indicate the elimination of stabilizing control involving the specific conductive pathways and, possibly, an accelerated conduction of a specific sensor signal.

  6. Potential Effects of Pomegranate Polyphenols in Cancer Prevention and Therapy.

    Science.gov (United States)

    Turrini, Eleonora; Ferruzzi, Lorenzo; Fimognari, Carmela

    2015-01-01

    Cancer is the second leading cause of death and is becoming the leading one in old age. Vegetable and fruit consumption is inversely associated with cancer incidence and mortality. Currently, interest in a number of fruits high in polyphenols has been raised due to their reported chemopreventive and/or chemotherapeutic potential. Pomegranate has been shown to exert anticancer activity, which is generally attributed to its high content of polyphenols. This review provides a comprehensive analysis of known targets and mechanisms along with a critical evaluation of pomegranate polyphenols as future anticancer agents. Pomegranate evokes antiproliferative, anti-invasive, and antimetastatic effects, induces apoptosis through the modulation of Bcl-2 proteins, upregulates p21 and p27, and downregulates cyclin-cdk network. Furthermore, pomegranate blocks the activation of inflammatory pathways including, but not limited to, the NF-κB pathway. The strongest evidence for its anticancer activity comes from studies on prostate cancer. Accordingly, some exploratory clinical studies investigating pomegranate found a trend of efficacy in increasing prostate-specific antigen doubling time in patients with prostate cancer. However, the genotoxicity reported for pomegranate raised certain concerns over its safety and an accurate assessment of the risk/benefit should be performed before suggesting the use of pomegranate or its polyphenols for cancer-related therapeutic purposes.

  7. Effects of discontinuities of the derivatives of the inflaton potential

    Energy Technology Data Exchange (ETDEWEB)

    Gallego Cadavid, Alexander [Universidad de Antioquia, Instituto de Fisica, Medellin (Colombia); Kyoto University, Yukawa Institute for Theoretical Physics, Kyoto (Japan); Enea Romano, Antonio [Universidad de Antioquia, Instituto de Fisica, Medellin (Colombia); Kyoto University, Yukawa Institute for Theoretical Physics, Kyoto (Japan); University of Crete, Department of Physics, Heraklion (Greece)

    2015-12-15

    We study the effects of a class of features of the inflaton potential, corresponding to discontinuities in its derivatives. We perform fully numerical calculations and derive analytical approximations for the curvature perturbations spectrum and the bispectrum which are in good agreement with the numerical results. The spectrum of primordial perturbations has oscillations around the scale k{sub 0} which leaves the horizon at the time τ{sub 0} when the feature occurs, with the amplitude and phase of the oscillations determined by the size and the order of the discontinuity. The large scale bispectrum in the squeezed and equilateral limits have a very similar form and are linearly suppressed. Both in the squeezed and the equilateral small scale limit the bispectrum has an oscillatory behavior whose phase depends on the parameters determining the discontinuity, and whose amplitude is inversely proportional to the scale. Given the generality of this class of features they could be used to model or classify phenomenologically different types of non-Gaussian features encountered in observational data such as the cosmic microwave background radiation or large scale structure. (orig.)

  8. Potential estrogenic effects of phosphorus-containing flame retardants.

    Science.gov (United States)

    Zhang, Quan; Lu, Meiya; Dong, Xiaowu; Wang, Cui; Zhang, Chunlong; Liu, Weiping; Zhao, Meirong

    2014-06-17

    As the substitute of polybrominated diphenyl ethers (PBDEs), further assessments about the potential ecological safety and health risks of phosphorus-containing flame retardants (PFRs) are required because the worldwide demand for PFRs has been increasing every year. In this study, we examined the agonistic/antagonistic activity of a group of PFRs by three in vitro models (luciferase reporter gene assay, yeast two-hybrid assay, and E-screen assay). Molecule docking was used to further explain the interactions between ERα and PFRs. Data from luciferase reporter gene analysis showed three members of the nine tested PFRs significantly induced estrogenic effects, with the order of TPP > TCP > TDCPP, while TCEP and TEHP have remarkable antiestrogenic properties with calculated REC20 and RIC20 values of 10(-6) M or lower. Results from the luciferase reporter gene method are generally consistent with results obtained from the yeast two-hybrid assay and E-screen, except for the positive estrogenic activity of TBP in E-screen testing. Docking results showed that binding between ligands and ERα was stabilized by hydrophobic interactions. As a proposed alternative for brominated flame retardant, PFRs may have anti/estrogenic activity via ERα at the low dose typical of residue in environmental matrix or animals. PFRs with a short chain, halogen, and benzene ring in the substituent group tend to be estrogenic. Our research suggests that comprehensive evaluations, including health and ecological assessments, are required in determining whether PFRs are preferable as an emerging industrial substitute.

  9. Potential Therapeutic Effects of Meditation for Treating Affective Dysregulation

    Directory of Open Access Journals (Sweden)

    Natalie T. Y. Leung

    2014-01-01

    Full Text Available Affective dysregulation is at the root of many psychopathologies, including stress induced disorders, anxiety disorders, and depression. The root of these disorders appears to be an attenuated, top-down cognitive control from the prefrontal cortices over the maladaptive subcortical emotional processing. A form of mental training, long-term meditation practice can trigger meditation-specific neuroplastic changes in the brain regions underlying cognitive control and affective regulation, suggesting that meditation can act as a kind of mental exercise to foster affective regulation and possibly a cost-effective intervention in mood disorders. Increasing research has suggested that the cultivation of awareness and acceptance along with a nonjudgmental attitude via meditation promotes adaptive affective regulation. This review examined the concepts of affective regulation and meditation and discussed behavioral and neural evidence of the potential clinical application of meditation. Lately, there has been a growing trend toward incorporating the “mindfulness” component into existing psychotherapeutic treatment. Promising results have been observed thus far. Future studies may consider exploring the possibility of integrating the element of “compassion” into current psychotherapeutic approaches.

  10. Effects of discontinuities of the derivatives of the inflaton potential

    Energy Technology Data Exchange (ETDEWEB)

    Cadavid, Alexander Gallego [Instituto de Fisica, Universidad de Antioquia, A.A.1226, Medellin (Colombia); Yukawa Institute for Theoretical Physics, Kyoto University, Kyoto (Japan); Romano, Antonio Enea, E-mail: aer@physics.uoc.gr [Instituto de Fisica, Universidad de Antioquia, A.A.1226, Medellin (Colombia); Yukawa Institute for Theoretical Physics, Kyoto University, Kyoto (Japan); Department of Physics, University of Crete, 71003, Heraklion (Greece)

    2015-12-12

    We study the effects of a class of features of the inflaton potential, corresponding to discontinuities in its derivatives. We perform fully numerical calculations and derive analytical approximations for the curvature perturbations spectrum and the bispectrum which are in good agreement with the numerical results. The spectrum of primordial perturbations has oscillations around the scale k{sub 0} which leaves the horizon at the time τ{sub 0} when the feature occurs, with the amplitude and phase of the oscillations determined by the size and the order of the discontinuity. The large scale bispectrum in the squeezed and equilateral limits have a very similar form and are linearly suppressed. Both in the squeezed and the equilateral small scale limit the bispectrum has an oscillatory behavior whose phase depends on the parameters determining the discontinuity, and whose amplitude is inversely proportional to the scale. Given the generality of this class of features they could be used to model or classify phenomenologically different types of non-Gaussian features encountered in observational data such as the cosmic microwave background radiation or large scale structure.

  11. Supersymmetry of Demkov-Ostrovsky effective potentials at zero energy

    CERN Document Server

    Rosu, H C; Wolf, K B; Obregón, O; Rosu, Haret C; Reyes, Marco A; Wolf, Kurt Bernardo; Obregon, Octavio

    1995-01-01

    We present a Natanzon-type supersymmetric analysis of the wave problem with Demkov-Ostrovsky (DO) spherically symmetric class of focusing potentials at zero energy. It is known that at zero binding energy there exists a degenerate ``bound" state for this class of potentials. Working at zero energy and in the so-called R_{0}=0 sector, we obtain the corresponding superpartner (fermionic) DO scattering potentials within the standard one-dimensional supersymmetric procedure.

  12. Effect of fixation tasks on multifocal visual evoked potentials.

    Science.gov (United States)

    Martins, Alessandra; Klistorner, Alexander; Graham, Stuart; Billson, Frank

    2005-10-01

    This study investigated the effects of cognitive influence on the multifocal visual evoked potential (mVEP) at different levels of eccentricity. Three different foveal fixation conditions were utilized involving varying levels of task complexity. A more complex visual fixation task has been known to suppress peripheral signals in subjective testing. Twenty normal subjects had monocular mVEPs recorded using the AccuMap objective perimeter. This allowed simultaneous stimulation of 58 segments of the visual field to an eccentricity of 24 degrees. The mVEP was recorded using three different fixation conditions in random order. During task 1 the subject passively viewed the central fixation area. For task 2 alternating numbers were displayed within the fixation area; the subject on viewing the number '3' in the central fixation area indicated recognition by pressing a button. Throughout task 3, numbers were displayed as in task 2. The subject had the cognitive task of summating all the numbers. Analysis revealed that the increased attention and concentration demanded by tasks 2 and 3 in comparison with task 1 resulted in significantly enhanced central amplitudes of 9.41% (Mann-Whitney P = 0.0002) and 13.45% (P = 0.0002), respectively. These amplitudes became reduced in the periphery and approached those of task 1, resulting in no significant difference between the three tasks. Latencies demonstrated no significant difference between each task nor at any eccentricity (P > 0.05). As the complexity of each task increased the amount of alpha rhythm was significantly reduced. Our findings indicate that task 1 required a minimal demand of cognition and was associated with the greatest amount of alpha rhythm. It was also the most difficult to perform because of loss of interest. The other two tasks required a greater demand of higher order cognitive skills resulting in significantly enhanced amplitudes centrally and the attenuation of alpha rhythm. Therefore, amplitudes are

  13. Estimating Potential Effects of Hypothetical Oil Spills on Polar Bears

    Science.gov (United States)

    Amstrup, Steven C.; Durner, G.M.; McDonald, T.L.; Johnson, W.R.

    2006-01-01

    Much is known about the transport and fate of oil spilled into the sea and its toxicity to exposed wildlife. Previously, however, there has been no way to quantify the probability that wildlife dispersed over the seascape would be exposed to spilled oil. Polar bears, the apical predator of the arctic, are widely dispersed near the continental shelves of the Arctic Ocean, an area also undergoing considerable hydrocarbon exploration and development. We used 15,308 satellite locations from 194 radiocollared polar bears to estimate the probability that polar bears could be exposed to hypothetical oil spills. We used a true 2 dimensional Gausian kernel density estimator, to estimate the number of bears likely to occur in each 1.00 km2 cell of a grid superimposed over near shore areas surrounding 2 oil production facilities: the existing Northstar oil production facility, and the proposed offshore site for the Liberty production facility. We estimated the standard errors of bear numbers per cell with bootstrapping. Simulated oil spill footprints for September and October, the times during which we hypothesized effects of an oil-spill would be worst, were estimated using real wind and current data collected between 1980 and 1996. We used ARC/Info software to calculate overlap (numbers of bears oiled) between simulated oil-spill footprints and polar bear grid-cell values. Numbers of bears potentially oiled by a hypothetical 5912 barrel spill (the largest spill thought probable from a pipeline breach) ranged from 0 to 27 polar bears for September open water conditions, and from 0 to 74 polar bears in October mixed ice conditions. Median numbers oiled by the 5912 barrel hypothetical spill from the Liberty simulation in September and October were 1 and 3 bears, equivalent values for the Northstar simulation were 3 and 11 bears. In October, 75% of trajectories from the 5912 barrel simulated spill at Liberty oiled 9 or fewer bears while 75% of the trajectories affected 20 or

  14. Testing high-Z QED with SuperEBIT: An estimate of the U{sup 91+}1s two-loop Lamb shift based on a measurement of the 2s{sub 1/2}-2p{sub 1/2} transition in U{sup 89+}

    Energy Technology Data Exchange (ETDEWEB)

    Beiersdorfer, Peter [University of California Lawrence Livermore National Laboratory, Livermore, CA 94550 (United States)]. E-mail: beiersdorfer@llnl.gov

    2006-11-15

    Starting from the results of a recent measurement of the 2s{sub 1/2}-2p{sub 1/2} transition in U{sup 89+} made on the SuperEBIT electron beam ion trap, which provided a determination of the 2s two-loop QED contribution, we estimate 1.27+/-0.45eV for the two-loop contribution to the 1s level in U{sup 91+}. This estimate could be improved by a factor of two or more, if the uncertainties associated with the three-photon exchange in the theoretical calculations were eliminated in the future.

  15. EFFECTIVE DIFFUSION AND EFFECTIVE DRAG COEFFICIENT OF A BROWNIAN PARTICLE IN A PERIODIC POTENTIAL

    Institute of Scientific and Technical Information of China (English)

    Hongyun Wang

    2011-01-01

    We study the stochastic motion of a Brownian particle driven by a constant force over a static periodic potential.We show that both the effective diffusion and the effective drag coefficient are mathematically well-defined and we derive analytic expressions for these two quantities.We then investigate the asymptotic behaviors of the effective diffusion and the effective drag coefficient,respectively,for small driving force and for large driving force.In the case of small driving force,the effective diffusion is reduced from its Brownian value by a factor that increases exponentially with the amplitude of the potential.The effective drag coefficient is increased by approximately the same factor.As a result,the Einstein relation between the diffusion coefficient and the drag coefficient is approximately valid when the driving force is small.For moderately large driving force,both the effective diffusion and the effective drag coefficient are increased from their Brownian values,and the Einstein relation breaks down. In the limit of very large driving force,both the effective diffusion and the effective drag coefficient converge to their Brownian values and the Einstein relation is once again valid.

  16. Effect of electric potential and heating on surface of KCI

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    @@ The purpose of the work is research of morphology of structural changes of a surface { 100} crystals KCl under action of heating and electric field potential enclosed to one of fasets of a crystal.

  17. Effect of electric potential and heating on surface of KCI

    Institute of Scientific and Technical Information of China (English)

    Feodorov; Victor; A.; Sterelukhin; Andrey; A.; Karyev; Leonid; G.

    2005-01-01

    The purpose of the work is research of morphology of structural changes of a surface { 100} crystals KCl under action of heating and electric field potential enclosed to one of fasets of a crystal.……

  18. Compactification of gauge models and the effective potential

    Energy Technology Data Exchange (ETDEWEB)

    Shtykov, N.N. (Leningrad State University, Leningrad (SU))

    1989-07-01

    The one-loop potential for bosons and massive fermions in an Abelian model is obtained on the {ital M}{sup 2}{times}{ital S1}{times}{ital S1} manifold. Stability of the total potential against arbitrary homogeneous deformations of {ital S}{sup 1}{times}{ital S1} is studied. It is shown that attraction or repulsion depends on the relations connecting the radii of the spheres, the fermion masses, and the coupling constant.

  19. Proprioceptive event related potentials: gating and task effects

    DEFF Research Database (Denmark)

    Arnfred, Sidse M

    2005-01-01

    The integration of proprioception with vision, touch or audition is considered basic to the developmental formation of perceptions, conceptual objects and the creation of cognitive schemes. Thus, mapping of proprioceptive information processing is important in cognitive research. A stimulus...... of a brisk change of weight on a hand held load elicit a proprioceptive evoked potential (PEP). Here this is used to examine early and late information processing related to weight discrimination by event related potentials (ERP)....

  20. Effects of Asymmetry of Potential on Stochastic Stokes' Drift

    Institute of Scientific and Technical Information of China (English)

    LI Yu-Xiao; CAO Tian-Guang; WU Xi-Zhen; ZHUO Yi-Zhong

    2001-01-01

    The directed motion of Brownian particles is generated by a travelling asymmetric potential The asymptotic behaviour of the probability density of the particles at a long tie is a solitary wave. The Brownian particles can work against an external opposing force with high efficiency. The analytical expressions of the solitary wave and the efficiency of the Brownian particles are obtained. The average velocity and the efficiency of the particles depends strongly on the travelling speed and the asymmetry of the potential.

  1. Effects of Nonlocal One-Pion-Exchange Potential in Deuteron

    OpenAIRE

    Forest, J. L.

    1999-01-01

    The off-shell aspects of the one-pion-exchange potential (OPEP) are discussed. Relativistic Hamiltonians containing relativistic kinetic energy, relativistic OPEP with various off-shell behaviors and Argonne $v_{18}$ short-range parameterization are used to study the deuteron properties. The OPEP off-shell behaviors depend on whether a pseudovector or pseudoscalar pion-nucleon coupling is used and are characterized by a parameter $\\mu$. We study potentials having $\\mu$=-1, 0 and +1 and we fin...

  2. Effects of Nonlocal One-Pion-Exchange Potential in Deuteron

    CERN Document Server

    Forest, J L

    2000-01-01

    The off-shell aspects of the one-pion-exchange potential (OPEP) are discussed. Relativistic Hamiltonians containing relativistic kinetic energy, relativistic OPEP with various off-shell behaviors and Argonne $v_{18}$ short-range parameterization are used to study the deuteron properties. The OPEP off-shell behaviors depend on whether a pseudovector or pseudoscalar pion-nucleon coupling is used and are characterized by a parameter $\\mu$. We study potentials having $\\mu$=-1, 0 and +1 and we find that they are nearly unitarily equivalent. We also find that a nonrelativistic Hamiltonian containing local potentials and nonrelativistic kinetic energy provides a good approximation to a Hamiltonian containing a relativistic OPEP based on pseudovector pion-nucleon coupling and relativistic kinetic energy.

  3. Long Range Potential Effects in Low Density Krypton Gas

    Energy Technology Data Exchange (ETDEWEB)

    Formisano, F.; Barocchi, F. [Dipartimento di Fisica, Universita degli Studi di Firenze, Largo E. Fermi 2, I-50125 Firenze (Italy); Formisano, F.; Barocchi, F.; Magli, R. [Istituto Nazionale di Fisica della Materia, Sezione di Firenze, Largo E. Fermi 2, I-50125 Firenze (Italy); Benmore, C.J.; Egelstaff, P.A. [Physics Department, University of Guelph, Ontario, N1G 2W1 (CANADA); Bafile, U. [Istituto di Elettronica Quantistica, Consiglio Nazionale delle Ricerche, Via Panciatichi 56/30, I-50127 Firenze (Italy); Magli, R. [Dipartimento di Energetica S. Stecco, Universita degli Studi di Firenze, Via di S. Marta 3, I-50139 Firenze (Italy); Verkerk, P. [Interfacultair Reactor Instituut, Technische Universiteit Delft, 2629 JB Delft (The Netherlands)

    1997-07-01

    Small angle neutron scattering (SANS) in low density {sup 86}Kr gas has been performed in order to measure the small-k behavior of the static structure factor S(k) . Three number densities between 1.52 and 2.42 nm{sup {minus}3} along the T=297 K isotherm have been studied. The small-k dependence of the Fourier transform c(k) of the direct correlation function c(r) has been derived. The experimental determination of the k{sup 3} term in the behavior of c(k) has led to a direct measurement of the London dispersion interaction in the pair potential of krypton. Also the contribution of the three-body potential in the asymptotic behavior of c(r) has been observed and related to the magnitude of the three-body interaction potential. {copyright} {ital 1997} {ital The American Physical Society}

  4. Heavy quark potential from QCD-related effective coupling

    Science.gov (United States)

    Ayala, César; González, Pedro; Vento, Vicente

    2016-12-01

    We implement our past investigations of quark-antiquark interaction through a non-perturbative running coupling defined in terms of a gluon mass function, similar to that used in some Schwinger-Dyson approaches. This coupling leads to a quark-antiquark potential, which satisfies not only asymptotic freedom but also describes linear confinement correctly. From this potential, we calculate the bottomonium and charmonium spectra below the first open flavor meson-meson thresholds and show that for a small range of values of the free parameter determining the gluon mass function an excellent agreement with data is attained.

  5. Relativistic and quantum electrodynamics effects in the helium pair potential.

    Science.gov (United States)

    Przybytek, M; Cencek, W; Komasa, J; Łach, G; Jeziorski, B; Szalewicz, K

    2010-05-01

    The helium pair potential was computed including relativistic and quantum electrodynamics contributions as well as improved accuracy adiabatic ones. Accurate asymptotic expansions were used for large distances R. Error estimates show that the present potential is more accurate than any published to date. The computed dissociation energy and the average R for the (4)He(2) bound state are 1.62+/-0.03 mK and 47.1+/-0.5 A. These values can be compared with the measured ones: 1.1(-0.2)(+0.3) mK and 52+/-4 A [R. E. Grisenti, Phys. Rev. Lett. 85, 2284 (2000)].

  6. Music listening after stroke: beneficial effects and potential neural mechanisms

    National Research Council Canada - National Science Library

    Särkämö, Teppo; Soto, David

    2012-01-01

    .... Then we will present findings about the short‐ and long‐term effects of music listening on the recovery of cognitive function in stroke patients and the underlying neural mechanisms of these music effects...

  7. Mind games : the effects of diazepam on Evoked Potentials

    NARCIS (Netherlands)

    Jongsma, Marie-Louise Albertien

    2000-01-01

    The electroencephalogram (EEG) represents the electrical activity of the brain. Evoked Potentials (EPs) are small voltage fluctuations in the EEG resulting from sensory, cognitive or motor evoked neural activity. Variations in the EP waveform may be caused by several factors. 1. By employing differe

  8. Tetrandrine potentiated hypnotic effect of pentobarbital through serotonergic system

    Institute of Scientific and Technical Information of China (English)

    XinZHAO; Yong-heZHAN; Xiang-yuCUI; Bao-qiongCHEN

    2004-01-01

    AIM: To investigate the hypnotic activity and mechanism of tetrandrine (TET, a major component of Stephania tetrandrae) in mice. METHODS: Each mouse was observed for the onset and duration of sleep, with the criterion for sleep being loss of righting reflex. RESULTS: TET potentiated pentobarbital (45 mg/kg, ip)-induced hypnosis significantly by reducing sleep latency and

  9. The effect of nonlinearity in relativistic nucleon–nucleon potential

    Indian Academy of Sciences (India)

    B B Sahu; S K Singh; M Bhuyan; S K Patra

    2014-04-01

    A simple form for nucleon–nucleon (NN) potential is introduced as an alternative to the popular M3Y form using the relativistic mean field theory (RMFT) with the non-linear terms in -meson for the first time. In contrast to theM3Y form, the new interaction becomes exactly zero at a finite distance and the expressions are analogous with the M3Y terms. Further, its applicability is examined by the study of proton and cluster radioactivity by folding it with the RMFT-densities of the cluster and daughter nuclei to obtain the optical potential in the region of proton-rich nuclides just above the double magic core 100Sn. The results obtained were found comparable with the widely used M3Y interactions.

  10. Reduction of Electronic Wavefunctions to Kohn-Sham Effective Potentials

    CERN Document Server

    Ryabinkin, Ilya G; Staroverov, Viktor N

    2015-01-01

    A method for calculating the Kohn--Sham exchange-correlation potential, $v_\\text{XC}(\\mathbf{r})$, from a given electronic wavefunction is devised and implemented. It requires on input one- and two-electron density matrices and involves construction of the generalized Fock matrix. The method is free from numerical limitations and basis-set artifacts of conventional schemes for constructing $v_\\text{XC}(\\mathbf{r})$ in which the potential is recovered from a given electron density, and is simpler than various many-body techniques. The chief significance of this development is that it allows one to directly probe the functional derivative of the true exchange-correlation energy functional and to rigorously test and improve various density-functional approximations.

  11. [Effects of nicotine on visually evoked EEG potentials].

    Science.gov (United States)

    Woodson, P P; Bättig, K; Rosecrans, J A

    1982-10-01

    The effects of nicotine were measured on the averaged visual evoked response (AVER) through the use of two types of experimental cigarettes which differed only in nicotine content (i.e., 0.14 vs. 1.34 mg/cig.). The results indicate that the restorative and/or enhancing effects of cigarette smoking on peak amplitudes are due predominantly to nicotine's psychopharmacologic effects, and support past research indicating that nicotine may enhance visual attentional processes in the quiescent smoker. This contrasts with other reports indicating nicotine to have a depressant effect on auditory processes.

  12. Analysis of some potential social effects of four coal technologies

    Energy Technology Data Exchange (ETDEWEB)

    Walker, C.A.; Gould, L.C.

    1980-09-01

    This is an analysis of the potential social impacts of four coal technologies: conventional combustion, fluidized-bed combustion, liquifaction, and gasification. Because of their flexibility, and the abundance and relatively low costs of coal, the potential benefits of these technologies would seem to outweigh their potential social costs, both in the intermediate and long term. Nevertheless, the social costs of a coal industry are far more obscure and hard to quantify than the benefits. In general, however, it maybe expected that those technologies that can be deployed most quickly, that provide fuels that can substitute most easily for oil and natural gas, that are the cheapest, and that are the most thermally efficient will minimize social costs most in the intermediate term, while technologies that can guide energy infrastructure changes to become the most compatable with the fuels that will be most easily derived from inexhaustible sources (electricity and hydrogen) will minimize social costs most in the long run. An industry structured to favor eastern over western coal and plant sites in moderate sized communities, which could easily adapt to inexhaustible energy technologies (nuclear or solar) in the future, would be favored in either time period.

  13. Newer Approaches to Identify Potential Untoward Effects in Functional Foods.

    Science.gov (United States)

    Marone, Palma Ann; Birkenbach, Victoria L; Hayes, A Wallace

    2016-01-01

    Globalization has greatly accelerated the numbers and variety of food and beverage products available worldwide. The exchange among greater numbers of countries, manufacturers, and products in the United States and worldwide has necessitated enhanced quality measures for nutritional products for larger populations increasingly reliant on functionality. These functional foods, those that provide benefit beyond basic nutrition, are increasingly being used for their potential to alleviate food insufficiency while enhancing quality and longevity of life. In the United States alone, a steady import increase of greater than 15% per year or 24 million shipments, over 70% products of which are food related, is regulated under the Food and Drug Administration (FDA). This unparalleled growth has resulted in the need for faster, cheaper, and better safety and efficacy screening methods in the form of harmonized guidelines and recommendations for product standardization. In an effort to meet this need, the in vitro toxicology testing market has similarly grown with an anticipatory 15% increase between 2010 and 2015 of US$1.3 to US$2.7 billion. Although traditionally occupying a small fraction of the market behind pharmaceuticals and cosmetic/household products, the scope of functional food testing, including additives/supplements, ingredients, residues, contact/processing, and contaminants, is potentially expansive. Similarly, as functional food testing has progressed, so has the need to identify potential adverse factors that threaten the safety and quality of these products.

  14. University students' psychopathology: correlates and the examiner's potential bias effect

    Directory of Open Access Journals (Sweden)

    Helena Espirito Santo

    2015-02-01

    Aims: the main objective was to verify if there is a difference on psychopathological symptoms between two groups questioned by two different examiners, controlling for the potential role of social desirability, and other potential covariates. Additionally, we want to assess the level of psychopathology and its socio-demographic correlates.Methods: 185 Coimbra's university students completed the Brief Symptom Inventory/BSI and the Marlowe-Crowne Social Desirability Scale. In one group the examiner was of the same age and academic status as the students, while in the other group the examiner was older and a teacher. We studied the psychopathological correlates with Pearson, point-biserial correlations, and qui-square analyses, and we controlled the potential role of covariates through Quade non-parametric ANCOVAs. Results: The level of distress was lower in comparison with other investigations. Women had higher level of distress and more symptoms of somatization, anxiety, phobic anxiety, obsessive-compulsion, and depression. The students that live a higher distance from home had more anxiety and obsessive-compulsive symptoms. The group assessed by the younger examiner scored higher in distress and in some BSI factors, and had lower levels on social desirability. Conclusions: Sex and distance from home seem important factors for university students' mental health. However, the examiner does have an influence in the evaluation, probably because of social desirability, suggesting that the examiner's characteristics should be given in investigations involving university students.

  15. NLL resummation for the static potential in N=4 SYM theory

    Energy Technology Data Exchange (ETDEWEB)

    Stahlhofen, Maximilian [Wien Univ. (Austria). Fakultaet fuer Physik

    2012-09-15

    We determine the complete NLL running of the static potential associated with the locally 1/2 BPS Wilson loop in N=4 supersymmetric Yang-Mills theory. We present results for the SU(N{sub c}) singlet as well as for the adjoint configuration and arbitrary N{sub c} at weak coupling. In order to derive the respective anomalous dimensions we perform a two-loop calculation in the N=4 supersymmetric version of the effective field theory pNRQCD. In addition we confirm the recently obtained fixed-order result for the singlet static potential generated exclusively by ladder diagrams to the third order in the t'Hooft coupling. We also give an explicit expression for the logarithmic contribution of all non-ladder diagrams at this order.

  16. Quantum vacuum effects from boundaries of designer potentials

    NARCIS (Netherlands)

    Konopka, T.J.

    2009-01-01

    Vacuum energy in quantum field theory, being the sum of zero-point energies of all field modes, is formally infinite but yet, after regularization or renormalization, can give rise to finite observable effects. One way of understanding how these effects arise is to compute the vacuum energy in an id

  17. Slow high-frequency effects in mechanics: problems, solutions, potentials

    DEFF Research Database (Denmark)

    Thomsen, Jon Juel

    Strong high-frequency excitation (HFE) may change the ‘slow’ (i.e. effective or average) properties of mechanical systems, e.g. their stiffness, natural frequencies, equilibriums, equilibrium stability, and bifurcation paths. This tutorial describes three general HFE effects: Stiffening – an appa......Strong high-frequency excitation (HFE) may change the ‘slow’ (i.e. effective or average) properties of mechanical systems, e.g. their stiffness, natural frequencies, equilibriums, equilibrium stability, and bifurcation paths. This tutorial describes three general HFE effects: Stiffening...... and compared: The Method of Direct Separation of Motions, the Method of Averaging, and the Method of Multiple Scales. The tutorial concludes by suggesting that more vibration experts, researchers and students should know about HFE effects, for the benefit not only of general vibration troubleshooting, but also...

  18. An effective theory for QCD with an axial chemical potential

    CERN Document Server

    Andrianov, Alexander A; Espriu, Domenec; Planells, Xumeu

    2013-01-01

    We consider the low energy realization of QCD in terms of meson fields when an axial chemical potential is present; a situation that may be relevant in heavy ion collisions. We shall demonstrate that the presence of an axial charge constitutes an explicit source of parity breaking. The eigenstates of strong interactions do not have a definite parity and interactions that would otherwise be forbidden compete with the familiar ones. In this work, we first focus on scalars and pseudoscalars that are described by a generalized linear sigma model; and next, we give some hints on how the Vector Meson Dominance model describes the vector sector.

  19. The potential protective effects of erythropoietin and estrogen on ...

    African Journals Online (AJOL)

    Noha I. Hussien

    2015-12-30

    Dec 30, 2015 ... Conclusion: It seems that EPO could protect the kidney against RIR, while this protective effect ... EPO is an essential growth factor of hemopoietic progeni- ...... Jerald Mahesh, Kuncha Madhusudana, Rachamalla Shyam Sun-.

  20. Effective potential for Polyakov loops in lattice QCD

    Science.gov (United States)

    Nemoto, Y.; RBC Collaboration

    2003-05-01

    Toward the derivation of an effective theory for Polyakov loops in lattice QCD, we examine Polyakov loop correlation functions using the multi-level algorithm which was recently developed by Luscher and Weisz.

  1. Action-specific effects in perception and their potential applications

    OpenAIRE

    Witt, Jessica K.; Linkenauger, Sally; Wickens, Chris

    2016-01-01

    Spatial perception is biased by action. Hills appear steeper and distances appear farther to individuals who would have to exert more effort to transverse the space. Objects appear closer, smaller, and faster when they are easier to obtain. Athletes who are playing better than others see their targets as bigger. These phenomena are collectively known as action-specific effects on perception. In this target article, we review evidence for action-specific effects, including evidence that they r...

  2. Potential effects of climate change on ecosystem distribution in Alberta

    Energy Technology Data Exchange (ETDEWEB)

    Schneider, R.R.; Farr, D.; Boutin, S. [Alberta Univ., Edmonton, AB (Canada). Dept. of Biological Sciences; Hamann, A.; Wang, X. [Alberta Univ., Edmonton, AB (Canada). Dept of Renewable Resources

    2009-05-15

    This paper proposed a method of extending the utility of bioclimatic envelope models for land use planning and adaptation under climate change. The trajectory of vegetation changes was set by the model, while the rate of transition was determined using a disturbance model. The method was used to explore potential changes to the distribution of ecosystems in Alberta under various climate and disturbance scenarios. The study showed that use of the disturbance model slowed the rate of ecosystem transition when compared with the results obtained from the bioclimatic envelope model alone. A northward shift of grasslands into large areas of existing parklands occurred over the simulation's 50-year time period. Between 12 and 21 per cent of Alberta's Boreal region was converted to parklands. Boreal transitions will initially occur in forests adjacent to current parklands and spread outwards. Fires over 100 km {sup 2} provided an indication of the anticipated size of potential transition patches. It was concluded that using a disturbance model to quantify transition logs can improve uncertainties in the parameter estimates of bioclimatic envelope models. 43 refs., 3 tabs., 3 figs.

  3. Potential Cost-Effective Opportunities for Methane Emission Abatement

    Energy Technology Data Exchange (ETDEWEB)

    Warner, Ethan [Joint Inst. for Strategic Energy Analysis, Golden, CO (United States); Steinberg, Daniel [Joint Inst. for Strategic Energy Analysis, Golden, CO (United States); Hodson, Elke [U.S. Department of Energy, Washington, DC (United States); Heath, Garvin [Joint Inst. for Strategic Energy Analysis, Golden, CO (United States)

    2015-08-01

    The energy sector was responsible for approximately 84% of carbon dioxide equivalent (CO2e) greenhouse gas (GHG) emissions in the U.S. in 2012 (EPA 2014a). Methane is the second most important GHG, contributing 9% of total U.S. CO2e emissions. A large portion of those methane emissions result from energy production and use; the natural gas, coal, and oil industries produce approximately 39% of anthropogenic methane emissions in the U.S. As a result, fossil-fuel systems have been consistently identified as high priority sectors to contribute to U.S. GHG reduction goals (White House 2015). Only two studies have recently attempted to quantify the abatement potential and cost associated with the breadth of opportunities to reduce GHG emissions within natural gas, oil, and coal supply chains in the United States, namely the U.S. Environmental Protection Agency (EPA) (2013a) and ICF (2014). EPA, in its 2013 analysis, estimated the marginal cost of abatement for non-CO2 GHG emissions from the natural gas, oil, and coal supply chains for multiple regions globally, including the United States. Building on this work, ICF International (ICF) (2014) provided an update and re-analysis of the potential opportunities in U.S. natural gas and oil systems. In this report we synthesize these previously published estimates as well as incorporate additional data provided by ICF to provide a comprehensive national analysis of methane abatement opportunities and their associated costs across the natural gas, oil, and coal supply chains. Results are presented as a suite of marginal abatement cost curves (MACCs), which depict the total potential and cost of reducing emissions through different abatement measures. We report results by sector (natural gas, oil, and coal) and by supply chain segment - production, gathering and boosting, processing, transmission and storage, or distribution - to facilitate identification of which sectors and supply chain

  4. Cigarette smoke effects on innate immune mechanisms in the nasal mucosa. Potential effects on the microbiome.

    Science.gov (United States)

    Jaspers, Ilona

    2014-01-01

    It is well established that exposure to cigarette smoke (CS), through active smoking and through exposure to secondhand smoke, has immunosuppressive effects, yet how this might affect the microbiome is not known. In this manuscript we focus on the effects of CS on innate host defense response, with particular emphasis on the role of epithelial cells and mucosal immune responses in the nose and the potential effects on the microbiome. The studies described here briefly summarize the effects of CS on specific innate immune cells, such as neutrophils, macrophages/monocytes, natural killer cells, and dendritic cells. A detailed description of how CS affects epithelial cells and why we consider this to be a central defect in the overall immunosuppressive effects of CS in the lung is provided. We summarize data on the role of the "epimmunome" in the context of CS exposure, including the effects on soluble mediator production, such as cytokines, chemokines, and antimicrobial defense mediators. Separate emphasis is put on the expression of ligands on epithelial cells, which directly interact with receptors on immune cells, and the effects of CS on these interactions. We introduce the nose and nasal mucosa as a model to study the effects of CS exposure on host defense responses and changes in the microbiome in humans in vivo. Understanding the dynamics of a healthy microbiome and how CS affects this balance is important to uncovering the mechanisms of CS-induced disease.

  5. [Conservative therapy of female urinary incontinence--potential and effect].

    Science.gov (United States)

    Horcicka, L; Chmel, R; Novácková, M

    2005-01-01

    Non-surgical treatment of female stress urinary incontinence is not as effective as surgical methods but it is very successful in indicated cases. Rehabilitation of the pelvic floor muscles (Kegel exercises, vaginal cones, and electrostimulation of the pelvic floor muscles), drug treatment (alfa-mimetics, tricyclic antidepressives, estrogens, duloxetin), pessarotherapy and uretral obturator devices represent possibilities of conservative therapy of the stress incontinence. Conservative therapy is the method of choice in the treatment of urge incontinence. The most successful are anticholinergic drugs but they have very frequent serious side effects (dryness of the mucous membranes, accommodation disorders, constipation). Spasmolytics, estrogens and tricyclic antidepressives are the other popular used drugs. Life style modification, bladder training and electrostimulation represent very important parts of the conservative treatment. Effectiveness of the non-surgical treatment of both urge and stress urinary incontinence can not reach 100 percent but it helps very much in the quality of life improvement of incontinent women.

  6. Fluids in porous media. IV. Quench effect on chemical potential

    Science.gov (United States)

    Qiao, C. Z.; Zhao, S. L.; Liu, H. L.; Dong, W.

    2017-06-01

    It appears to be a common sense to measure the crowdedness of a fluid system by the densities of the species constituting it. In the present work, we show that this ceases to be valid for confined fluids under some conditions. A quite thorough investigation is made for a hard sphere (HS) fluid adsorbed in a hard sphere matrix (a quench-annealed system) and its corresponding equilibrium binary mixture. When fluid particles are larger than matrix particles, the quench-annealed system can appear much more crowded than its corresponding equilibrium binary mixture, i.e., having a much higher fluid chemical potential, even when the density of each species is strictly the same in both systems, respectively. We believe that the insight gained from this study should be useful for the design of functionalized porous materials.

  7. Effects of MPTP, MPP+ and paraquat on mitochondrial potential and oxidative stress

    OpenAIRE

    Lambert, Ce; Bondy, SC

    1989-01-01

    The effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), 1-methyl-4-phenylpyridinium (MPP+) and 1,1-dimethyl-4,4-bipyridinium (paraquat) upon the electrical potential across the plasma and mitochondrial membranes within synaptosomes has been investigated. MPTP selectively depressed plasma membrane potential while MPP+ specifically reduced mitochondrial potential. The structurally similar compound paraquat had no effect on either membrane potential. Enhancement of the lipid peroxidat...

  8. Review article : anthranoid laxatives and their potential carcinogenic effects

    NARCIS (Netherlands)

    van Gorkom, B A; de Vries, E G; Karrenbeld, A; Kleibeuker, J H

    1999-01-01

    Anthranoid laxatives are widely used laxatives of natural origin, Because of their chemical structure they are carried unabsorbed to the large bowel, where metabolism to the active aglycones takes place, These aglycones exert their laxative effect by damaging epithelial cells, which leads directly a

  9. Slow high-frequency effects in mechanics: problems, solutions, potentials

    DEFF Research Database (Denmark)

    Thomsen, Jon Juel

    2005-01-01

    and compared: The Method of Direct Separation of Motions, the Method of Averaging, and the Method of Multiple Scales. The tutorial concludes by suggesting that more vibration experts, researchers and students should know about HFE effects, for the benefit not only of general vibration troubleshooting, but also...

  10. Effects of captopril on the heart mechanisms and therapeutic potentials

    NARCIS (Netherlands)

    Graeff, Pieter Andries de

    1989-01-01

    This thesis describes the experimental and clinical effects of captopril on the heart. Captopril was the first angiotensin converting enzyme inhibitor for oral administration. This enzyme is responsiblef or the conversion of angiotensin I in angiotensinII , one of the most potent pressor substances

  11. Psychological Theory and Pedagogical Effectiveness: The Learning Promotion Potential Framework

    Science.gov (United States)

    Tomlinson, Peter

    2008-01-01

    Background: After a century of educational psychology, eminent commentators are still lamenting problems besetting the appropriate relating of psychological insights to teaching design, a situation not helped by the persistence of crude assumptions concerning the nature of pedagogical effectiveness. Aims: To propose an analytical or…

  12. NARDOSTACHYS JATAMANSI DC. POTENTIAL HERB WITH CNS EFFECTS

    OpenAIRE

    AMRITPAL SINGH,ANIL KUMAR, SANJIV DUGGAL

    2013-01-01

    Nardostachys jatamansi is classified as hypno-sedative in Ayurveda. It is used intreatment of insomnia, hysteria and depressive illness. The plant abounds insesquiterpenes predominantly; jatamansone and nardostachone. The plant hasdemonstrated several pharmacological activities including hepatoprotective, cardioprotective and hypolipidemic and antifungal. The significant effect is on the centralnervous system, as diverse pharmacological actions, ranging from sedative to nootropichave been rep...

  13. Modeling Potentially Time-Varying Effects of Promotions on Sales

    NARCIS (Netherlands)

    Ph.H.B.F. Franses (Philip Hans); R. Paap (Richard); Ph.A. Sijthoff

    2001-01-01

    textabstractA commonly applied modeling tool for the analysis of promotional effects on weekly sales data is a linear regression model. Usually, such a model includes 0/1 dummy variables for promotions, where weeks with a promotion get a value of 1. When these variables are included in a model with

  14. Antidiabetic potentials of Momordica charantia: multiple mechanisms behind the effects.

    Science.gov (United States)

    Chaturvedi, Padmaja

    2012-02-01

    Momordica charantia fruits are used as a vegetable in many countries. From time immemorial, it has also been used for management of diabetes in the Ayurvedic and Chinese systems of medicine. Information regarding the standardization of this vegetable for its usage as an antidiabetic drug is scanty. There are many reports on its effects on glucose and lipid levels in diabetic animals and some in clinical trials. Reports regarding its mechanism of action are limited. So in the present review all the information is considered to produce some concrete findings on the mechanism behind its hypoglycemic and hypolipidemic effects. Studies have shown that M. charantia repairs damaged β-cells, increases insulin levels, and also enhance the sensitivity of insulin. It inhibits the absorption of glucose by inhibiting glucosidase and also suppresses the activity of disaccharidases in the intestine. It stimulates the synthesis and release of thyroid hormones and adiponectin and enhances the activity of AMP-activated protein kinase (AMPK). Effects of M. charantia like transport of glucose in the cells, transport of fatty acids in the mitochondria, modulation of insulin secretion, and elevation of levels of uncoupling proteins in adipose and skeletal muscles are similar to those of AMPK and thyroxine. Therefore it is proposed that effects of M. charantia on carbohydrate and fat metabolism are through thyroxine and AMPK.

  15. Skin-lightening cosmetics: frequent, potentially severe adverse effects.

    Science.gov (United States)

    2011-09-01

    Skin-lightening cosmetics are used by many women and men around the world. The products contain a variety of substances, which are often unknown to the users. Most of these products include topical corticosteroids, hydroquinone and mercury salts. Many other substances may be added. Several surveys and cohort studies, including several thousand individuals, have shown that regular application of skin-lightening cosmetics to large surface areas can have irreversible cutaneous adverse effects, such as patchy hyper- or hypopigmentation, skin atrophy, stretch marks and delayed wound healing, and can also mask or, on the contrary, promote or reactivate skin infections. Cases of skin cancer have been attributed to skin-lightening cosmetics. A Senegalese cohort study of 147 women showed a statistically significant increase in the risk of hypertension and diabetes linked to the use of skin-lightening agents. Other systemic adverse effects attributed to skin-lightening cosmetics include Cushing's syndrome, adrenal insufficiency, nephrotic syndrome, neurological disorders, and ocular disorders. Hypersensitivity reactions, including anaphylaxis, have also been attributed to these products. Many skin-lightening cosmetics contain substances that can harm the unborn child. For example, tretinoin is teratogenic while salicylic acid is feto-toxic. In practice, users are often unaware of the risk of severe adverse effects associated with skin-lightening cosmetics. Users should be informed of these adverse effects and encouraged to stop using these products, especially when skin disorders appear.

  16. Antioxidative actions of statins: potential mechanisms for antiathersclerotic effects.

    Science.gov (United States)

    Watanabe, Takanori; Yasunari, Kenichi; Nakamura, Munehoro

    2006-05-01

    Inhibitors of 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) reductase (statins) are widely used for the prevention of atherosclerotic diseases. The effects of statins on the generation of reactive oxygen species (ROS) by in vitro and in vivo were studied. Administration of statins significantly decreased ROS generation in vitro and in vivo.

  17. Ameliorative effect and potential mechanism of Ermiao san on ...

    African Journals Online (AJOL)

    of prostaglandin (PG) E2, tumor necrosis factor (TNF) -α and interleukin (IL)-1β in serum were determined by ... and toxic effects, expensive costs and limited efficacy spur ..... Xu Q, Yuan K, Lu J, Wang R, Wu F. A new strategy for regulating the ...

  18. Potential therapeutic effects of functionally active compounds isolated from garlic.

    Science.gov (United States)

    Yun, Hyung-Mun; Ban, Jung Ok; Park, Kyung-Ran; Lee, Chong Kil; Jeong, Heon-Sang; Han, Sang Bae; Hong, Jin Tae

    2014-05-01

    The medicinal properties of functionally active organosulfur compounds such as allin, diallyl disulfide, S-allylmercaptocysteine, and S-trityl-L-cysteine isolated from garlic have received great attention from a large number of investigators who have studied their pharmacological effects for the treatment of various diseases. These organosulfur compounds are able to prevent for development of cancer, cardiovascular, neurological, and liver diseases as well as allergy and arthritis. There have been also many reports on toxicities and pharmacokinetics of these compounds. The aim of this study is to review a variety of experimental and clinical reports, and describe the effectiveness, toxicities and pharmacokinetics, and possible mechanisms of pharmaceutical actions of functionally active compounds isolated from garlic. Copyright © 2013 Elsevier Inc. All rights reserved.

  19. Potential Health Effects of Enzymatic Protein Hydrolysates from Chlorella vulgaris

    OpenAIRE

    2016-01-01

    Background and Objective: Chlorella vulgaris is a multi-cellular edible algal species with abundant proteins. Extraction of high value protein fractions for pharmaceutical and nutritional applications can significantly increase the commercial value of microalga biomasses. There is no known report on the anticancer peptides derived from the Chlorella vulgaris abundant protein.Materials and Methods: This study examined the antimicrobial and anticancer effects of peptides from a hydrolyzed Chlor...

  20. Effects of stimulus duration on gustatory evoked potentials

    DEFF Research Database (Denmark)

    Rotvel, Camilla Arndal; Møller, Stine; Kivisaar, Kätlin

    The objective of the present study was to investigate the effect of tastant stimulus duration on the brain response. The brain response was measured by electroencephalography (EEG) which measures neural processes with high temporal resolution and may therefore complement sensory panel assessments...... sucralose stimulation duration resulted in larger GEP peak amplitude above the gustatory cortex and may indicate higher intensity perception (Kelling and Halpern, 1988)....

  1. Potentiating Effects of Lactuca sativa on Pentobarbital-Induced Sleep

    OpenAIRE

    Ghorbani, Ahmad; Rakhshandeh, Hassan; Sadeghnia, Hamid Reza

    2013-01-01

    Traditionally, Lactuca sativa (lettuce) has been recommended for its hypnotic property. The present study was planned to investigate sleep-prolonging effect of this plant. The hydro-alcoholic extract (HAE) of lettuce and its water fraction (WF), ethyl acetate fraction (EAF), and n-butanol fraction (NBF) were administrated (IP) to mice 30 min before the pentobarbital injection. Moreover, both in-vivo and in-vitro toxicity of the extracts were determined. The quality of HAE and NBF was also eva...

  2. Potential immunomodulatory effects of latent toxoplasmosis in humans

    Directory of Open Access Journals (Sweden)

    Stříž Ilja

    2011-10-01

    Full Text Available Abstract Background About 30% of the population worldwide are infected with the protozoan parasite Toxoplasma gondii. Latent toxoplasmosis has many specific behavioral and physiological effects on the human organism. Modified reactivity of the immune system has been suggested to play a key role in many of these effects. For example, the immunosuppression hypothesis explains the higher probability of the birth of male offspring observed in Toxoplasma-positive humans and mice by the protection of the (more immunogenic male embryos against abortion. Methods Here we searched for indices of immunosuppression in Toxoplasma-positive subjects by comparing clinical records of immunology outpatients. Results Our cohort study showed that the male patients with latent toxoplasmosis had decreased and the Toxoplasma-positive women had increased leukocyte, NK-cell and monocyte counts in comparison with controls. The B-cell counts were reduced in both Toxoplasma-positive men and women. The difference between Toxoplasma-positive and Toxoplasma-negative subjects diminished with the decline of the specific Toxoplasma antibody titre (a proxy for the length of infection, which is consistent with the observed decreasing strength of the effect of latent toxoplasmosis on human reproduction. The prevalence of toxoplasmosis in 128 male patients was unusually low (10.9% which contrasted with normal prevalence in 312 female patients (23.7% and in general population Prague (20-30%. Conclusions Latent toxoplasmosis has immunomodulatory effects in human and probably protects men against some classes of immunopathological diseases. The main limitation of the present study was the absence of the data on the immunoreactivity of immune cells subpopulations. Therefore further studies are needed to search for indices of immunosuppression in human using more specific markers.

  3. Potential Therapeutic Effects of Oleuropein Aglycone in Alzheimer's Disease.

    Science.gov (United States)

    Martorell, Miquel; Forman, Katherine; Castro, Natalia; Capó, Xavier; Tejada, Silvia; Sureda, Antoni

    Alzheimer's disease (AD) is an age-associated neurodegenerative amyloid disease and is considered a social and clinical problem the last decades, particularly in the Western countries. Amyloid diseases are characterized by the deposition of typically aggregated protein/peptides in tissues that are associated with brain degeneration and progressive cognitive impairment. The amyloid plaques and neurofibrillary tangles arise as a result of self-assembly into fibrillar material of amyloid-β protein and hyperphosphorylated tau, respectively. Moreover, mounting evidence shows that oxidative and nitrosative stress plays a central role in the pathogenesis of neurodegenerative disorders such as AD. Oleuropein belongs to a specific group of polyphenols, the secoiridoids, which are abundant in Oleaceae. Oleuropein aglycone is abundant in extra virgin olive oil and it is generated as a product of a glucosidase released when olive fruits are crushed. This secoiridoid compound has radical-scavenging activity and antioxidative effects and it is considered a promising target to prevent amyloid toxicity as an inhibitor of the oligomer nucleation and growth. The neuroprotective and antioxidant effects of flavonoids have been found to strongly depend on their structure and functional groups. Oleuropein aglycone counteracts amyloid aggregation and toxicity affecting different pathways: amyloid precursor protein processing, amyloid-β peptide and tau aggregation, autophagy impairment, and neuroinflammation. In the current work, available literature on oleuropein aglycone effects as antioxidant and inhibitor of amyloid deposits in AD is reviewed. Moreover, we discuss the chemistry, food sources and bioavailability of oleuropein aglycone.

  4. Effect of YSZ sintering temperature on mixed potential sensor performance

    Energy Technology Data Exchange (ETDEWEB)

    Sekhar, Praveen K [Los Alamos National Laboratory; Brosha, Eric L [Los Alamos National Laboratory; Rangachary, Mukundan [Los Alamos National Laboratory; Garzon, Fernando H [Los Alamos National Laboratory; Nelson, Mark A [Los Alamos National Laboratory; Toracco, Dennis [Los Alamos National Laboratory

    2009-01-01

    In this article, the influence of Yttria-Stabilized Zirconia (YSZ) sintering temperature on a Pt/YSZ/La{sub 0.8}Sr{sub 0.2}CrO{sub 3} mixed potential sensor performance is reported. The sintering temperature of YSZ was varied from 1000 to 1200 C. Mercury porosity measurements were performed to estimate the porosity and tortuosity of the YSZ sample as a function of sintering temperature. Further, the surface area of YSZ was computed by the BET method. After YSZ characterization, the unbiased and biased sensor response was recorded. The 1000 C sintered YSZ sample was taken as the reference for comparison purposes. Experimental results indicated a 30% reduction in porosity for the 1200 C sintered YSZ sample, accounting for a 14-fold increase in the sensor response rise time. In addition, for the same sample, a 13-fold increase in sensitivity was observed upon exposure to propylene (100 ppm), associated with a 76% reduction in surface area. The slow response time of the sensor with YSZ sintered at higher temperatures has been attributed to higher tortuosity (delay in gas permeation to the three phase interface). Whereas, reduced heterogeneous catalysis induced by lower surface area accounts for the rise in sensitivity levels. The optimum YSZ sintering temperature was found to lie between 1100 and 1150 C.

  5. Space Nutrition: Effects on Bone and Potential Nutrition Countermeasures

    Science.gov (United States)

    Smith, Scott M.

    2008-01-01

    Optimal nutrition will be critical for crew members who embark on space exploration missions. Nutritional assessment provides an opportunity to ensure that crewmembers begin their missions in optimal nutritional status, to document changes during a mission and , if necessary, to provide intervention to maintain that status throughout the mission, and to assesses changes after landing in order to facilitate the return to their normal status as soon as possible after landing. We report here the findings from our nutritional assessment of the US astronauts who participated in the first eight International Space Station (ISS) missions. Bone loss during space flight remains one of the most critical challenges to astronaut health on space exploration missions. An increase in bone resorption of ISS crew members after flight was indicated by several markers. Vitamin D status also remains a challenge for long-duration space travelers, who lack ultraviolet light exposure in the shielded craft. Many nutrients affect bone, including calcium, protein, fatty acids, sodium, and others. Data supporting their potential as countermeasures for space flight, as published in many papers, will be reviewed in this presentation. Defining nutrient requirements, and being able to provide and maintain those nutrients on exploration missions, will be critical for maintaining crew member health. Please note, this abstract is not required for the meeting. A presentation on the topics described above will be given. This abstract is for travel documentation only.

  6. Effect of pupil size on multifocal pattern visual evoked potentials.

    Science.gov (United States)

    Martins, Alessandra; Balachandran, Chandra; Klistorner, Alexander I; Graham, Stuart L; Billson, Francis A

    2003-08-01

    The purpose of this study was to investigate the influence of pupil diameter on the amplitude and latency of multifocal visual evoked potentials (mfVEP). The multifocal objective perimeter (Accumap; Objectivision) was used to stimulate the visual field at 56 sites extending to 32 degrees using a pseudo-random pattern stimulus. The mfVEP were recorded using bipolar occipital electrodes, 7 min/eye. Ten normal subjects were recruited from the community and one eye was randomly selected for testing. The mfVEP were recorded at four different pupil diameters (2 mm, 4 mm, 6 mm, 8 mm), obtained by applying tropicamide (0.5%) or pilocarpine (2%) in different dilutions. Appropriate refractive correction was provided to overcome cycloplegia and achieve a visual acuity of 6/7.5 or better. Analysis revealed that at most pupil diameters the normalized full field amplitude did not show significant variation, except at the most miotic pupil diameter (2 mm), where the amplitude became reduced, based on 2-way anova and Tukey's T method. There was, however, significant correlation between latency and pupil area (correlation coefficient: upper field -0.63, lower field -0.76). The results suggest that even in the presence of mydriatics or miotics, the mfVEP test can be used to assess diseases that affect amplitude, provided near correction is used. The interpretation of latency, however, must be made with caution, as a borderline conduction defect with a dilated pupil may appear normal.

  7. Potential effects of xanthone on inflammation status in atherosclerotic rats

    Directory of Open Access Journals (Sweden)

    Dwi Laksono Adiputro

    2013-02-01

    Method: A total of 32 Wistar rats were divided into four groups (n=8, including control, hypercholesterolemic diet groups, hypercholesterolemic diet + xanthone at dose 35; 70; and 140 mg/kg body weight (mg/kgBW. Control group received standard diet for 60 days. Hypercholesterolemic diet group received standard diet plus yellow egg, sheep oil, cholic acid, and pig oil for 60 days per oral. Analysis of nuclear factor-kappa beta p65/p50 distribution and tumor necrosis factor-alpha level, was done using enzyme linked immunosorbent assay technique. Analysis of nitric oxide level was done by colorimetric technique using spectrophotometer. Results: Hypercholesterolemic diet significantly increased nuclear factor-kappa beta p65/p50 distribution, tumor necrosis factor-alpha level, and nitric oxide level compared with the control group (p<0.05. Xanthone decreased nuclear factor-kappa beta p65/p50 distribution in line with the distribution at standard diet at doses 70 and 140 mg/kg body weight. Xanthone significantly decreased tumor necrosis factor-alpha level compared with atherosclerotic diet group at all doses, although it did not reach the level at standard diet. Xanthone decreased nitric oxide level, reaching the level at standard diet in all doses. Conclusion: Xanthone has antiinflammatory potentials by inhibiting distribution of nuclear factor-kappa beta p65/p50, decreasing tumor necrosis factor-alpha and nitric oxide level. [J Intercult Ethnopharmacol 2013; 2(1.000: 53-56

  8. Potentiation of Anticancer Drugs: Effects of Pentoxifylline on Neoplastic Cells

    Directory of Open Access Journals (Sweden)

    Miroslav Barancik

    2011-12-01

    Full Text Available The drug efflux activity of P-glycoprotein (P-gp, a product of the mdr1 gene, ABCB1 member of ABC transporter family represents a mechanism by which tumor cells escape death induced by chemotherapeutics. In this study, we investigated the mechanisms involved in the effects of pentoxifylline (PTX on P-gp-mediated multidrug resistance (MDR in mouse leukemia L1210/VCR cells. Parental sensitive mouse leukemia cells L1210, and multidrug-resistant cells, L1210/VCR, which are characterized by the overexpression of P-gp, were used as experimental models. The cells were exposed to 100 μmol/L PTX in the presence or absence of 1.2 μmol/L vincristine (VCR. Western blot analysis indicated a downregulation of P-gp protein expression when multidrug-resistant L1210/VCR cells were exposed to PTX. The effects of PTX on the sensitization of L1210/VCR cells to VCR correlate with the stimulation of apoptosis detected by Annexin V/propidium iodide apoptosis necrosis kit and proteolytic activation of both caspase-3 and caspase-9 monitored by Western blot analysis. Higher release of matrix metalloproteinases (MMPs, especially MMP-2, which could be attenuated by PTX, was found in L1210/VCR than in L1210 cells by gelatin zymography in electrophoretic gel. Exposure of resistant cells to PTX increased the content of phosphorylated Akt kinase. In contrast, the presence of VCR eliminated the effects of PTX on Akt kinase phosphorylation. Taken together, we conclude that PTX induces the sensitization of multidrug-resistant cells to VCR via downregulation of P-gp, stimulation of apoptosis and reduction of MMPs released from drug-resistant L1210/VCR cells. These facts bring new insights into the mechanisms of PTX action on cancer cells.

  9. Effects of experimental income on demand for potentially real cigarettes.

    Science.gov (United States)

    Koffarnus, Mikhail N; Wilson, Arlington George; Bickel, Warren K

    2015-03-01

    Cigarette demand, or the change in cigarette consumption as a function of price, is a measure of reinforcement that is associated with level of tobacco dependence and other clinically relevant measures, but the effects of experimentally controlled income on real-world cigarette consumption have not been examined. In this study, income available for cigarette purchases was manipulated to assess the effect on cigarette demand. Tobacco-dependent cigarette smokers (n = 15) who smoked 10-40 cigarettes per day completed a series of cigarette purchasing tasks under a variety of income conditions meant to mimic different weekly cigarette budgets: $280, approximately $127, $70, or approximately $32 per week. Prices of $0.12, $0.25, $0.50, and $1.00 per cigarette were assessed in each income condition. Participants were instructed to purchase as many cigarettes as they would like for the next week and to only consume cigarettes purchased in the context of the study. One price in 1 income condition was randomly chosen to be "real," and the cigarettes and the excess money in the budget for that condition were given to the participant. Results indicate that demand elasticity was negatively correlated with income. Demand intensity (consumption at low prices) was unrelated to income condition and remained high across incomes. These results indicate that the amount of income that is available for cigarette purchases has a large effect on cigarette consumption, but only at high prices. © The Author 2014. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  10. NARDOSTACHYS JATAMANSI DC. POTENTIAL HERB WITH CNS EFFECTS

    Directory of Open Access Journals (Sweden)

    AMRITPAL SINGH,ANIL KUMAR, SANJIV DUGGAL

    2013-09-01

    Full Text Available Nardostachys jatamansi is classified as hypno-sedative in Ayurveda. It is used intreatment of insomnia, hysteria and depressive illness. The plant abounds insesquiterpenes predominantly; jatamansone and nardostachone. The plant hasdemonstrated several pharmacological activities including hepatoprotective, cardioprotective and hypolipidemic and antifungal. The significant effect is on the centralnervous system, as diverse pharmacological actions, ranging from sedative to nootropichave been reported. Animal and clinical research with jatamansone, the active principleof the plant, has justified hypno-sedative claim of Ayurveda. The review summarizes,phytochemical and pharmacological investigations carried out on the plant.

  11. Late effects of breast cancer treatment and potentials for rehabilitation

    Energy Technology Data Exchange (ETDEWEB)

    Ewertz, Marianne (Dept. of Oncology, Odense Univ. Hospital, Odense (Denmark)); Bonde Jensen, Anders (Inst. of Clinical Research, Univ. of Southern Denmark (Denmark))

    2011-02-15

    Background. Breast cancer is the most frequent malignant disease among women world wide. Survival has been improving leading to an increasing number of breast cancer survivors, in the US estimated to about 2.6 million. Material and methods. The literature was reviewed with focus on data from the Nordic countries. Results. Local therapies such as breast cancer surgery and radiotherapy may cause persistent pain in the breast area, arm, and shoulder reported by 30-50% of patients after three to five years, lymphedema in 15-25% of patients, and restrictions of arm and shoulder movement in 35%. Physiotherapy is the standard treatment for the latter while no pain intervention trials have been published. Chemotherapy may cause infertility and premature menopause, resulting in vasomotor symptoms, sexual dysfunction, and osteoporosis, which are similar to the side effects of endocrine treatment in postmenopausal women. Awareness of cardiotoxicity is needed since anthracyclines, trastuzumab, and radiotherapy can damage the heart. Breast cancer survivors have an increased risk of a major depression and far from all receive adequate anti-depressive treatment. Other psychological symptoms include fear of recurrence, sleep disturbances, cognitive problems, fatigue, and sexual problems. Discussion. To improve rehabilitation, specific goals have to be formulated into national guidelines and high priority directed towards research into developing and testing new interventions for alleviating symptoms and side effects experienced by breast cancer survivors

  12. Gravitational effects on vanishing Higgs potential at the Planck scale

    CERN Document Server

    Haba, Naoyuki; Takahashi, Ryo; Yamaguchi, Yuya

    2014-01-01

    We investigate gravitational effects on so-called multiple point criticality principle (MPCP) at the Planck scale. The MPCP requires two degenerate vacua, whose necessary conditions are expressed by vanishing Higgs quartic coupling ($\\lambda(M_{\\rm Pl})=0$) and vanishing its $\\beta$-function ($\\beta_\\lambda(M_{\\rm Pl})=0$). In order to satisfy the conditions, we find that the top pole mass and the Higgs mass should be $170.8\\,{\\rm GeV} \\lesssim M_t\\lesssim 171.7\\, {\\rm GeV}$ and $M_h=125.7\\pm0.4\\, {\\rm GeV}$, respectively, as well as suitable magnitude of gravitational effects (a coefficient of gravitational contribution as $|a_\\lambda| > 2$). In this case, however, since the Higgs quartic coupling $\\lambda$ becomes negative below the Planck scale, two vacua are not degenerate. We find that $M_h \\gtrsim 131.5\\, {\\rm GeV}$ with $M_t \\gtrsim 174\\, {\\rm GeV}$ is required by the realization of the MPCP. Therefore, the MPCP at the Planck scale cannot be realized in the SM and also the SM with gravity since $M_h \\g...

  13. Potential effects of forest management on surface albedo

    Science.gov (United States)

    Otto, J.; Bréon, F.-M.; Schelhaas, M.-J.; Pinty, B.; Luyssaert, S.

    2012-04-01

    Currently 70% of the world's forests are managed and this figure is likely to rise due to population growth and increasing demand for wood based products. Forest management has been put forward by the Kyoto-Protocol as one of the key instruments in mitigating climate change. For temperate and boreal forests, the effects of forest management on the stand-level carbon balance are reasonably well understood, but the biophysical effects, for example through changes in the albedo, remain elusive. Following a modeling approach, we aim to quantify the variability in albedo that can be attributed to forest management through changes in canopy structure and density. The modelling approach chains three separate models: (1) a forest gap model to describe stand dynamics, (2) a Monte-Carlo model to estimate the probability density function of the optical path length of photons through the canopy and (3) a physically-based canopy transfer model to estimate the interaction between photons and leaves. The forest gap model provides, on a monthly time step the position, height, diameter, crown size and leaf area index of individual trees. The Monte-Carlo model computes from this the probability density function of the distance a photon travels through crown volumes to determine the direct light reaching the forest floor. This information is needed by the canopy transfer model to calculate the effective leaf area index - a quantity that allows it to correctly represent a 3D process with a 1D model. Outgoing radiation is calculated as the result of multiple processes involving the scattering due to the canopy layer and the forest floor. Finally, surface albedo is computed as the ratio between incident solar radiation and calculated outgoing radiation. The study used two time series representing thinning from below of a beech and a Scots pine forest. The results show a strong temporal evolution in albedo during stand establishment followed by a relatively stable albedo once the canopy

  14. Potential Effects of Disruptive Political Trends in International Tourism Market

    Directory of Open Access Journals (Sweden)

    Ali Öztüren

    2017-05-01

    Full Text Available The purpose of this paper is to discuss the prospective effects of the latest political incidences on the international tourism market. In this context, the arguments are based on the implications of the USA elections and the Brexit. The methodology of this paper comprises the discussion of the debates related to the recent political experiences. International tourism activities cannot be isolated from the political environment. It is clear that the new political incidences will require novel insights and strategies in conducting international tourism business globally. This paper provides a viewpoint of the today’s political scenarios that will certainly affect the international tourism market. It can be used to comprehend insights that can be used to plan the tourism futures.

  15. Potential therapeutic effects of oral bisphosphonates on the intestine.

    Science.gov (United States)

    Pazianas, Michael; Russell, R Graham G

    2011-12-01

    Bisphosphonates are the principal drugs prescribed for the prevention of osteoporotic fractures. They are bone specific but poorly absorbed. In oral formulations, almost 99% of the administered dose remains within the intestinal tract and reaches the small and large bowel. Although the nitrogen-containing bisphosphonates can irritate the distal esophageal/gastric mucosa, they improve drug-induced colitis in animal models and exhibit antitumor properties on intestinal cells in vitro. Several recent epidemiological studies provide evidence of a reduced risk of colorectal cancer in osteoporotic patients treated with oral bisphosphonates, notably alendronate. In this review, we will explore the possible mechanisms of action underlying these effects and raise the question of whether these agents might be used in the chemoprophylaxis against colorectal cancer. © 2012 New York Academy of Sciences.

  16. Bioavailability, metabolism and potential health protective effects of dietary flavonoids

    DEFF Research Database (Denmark)

    Bredsdorff, Lea

    the association between exposure to dietary flavonoids and the risk of acute coronary syndrome (ACS) in a nested case-control study. The bioavailability and metabolism of hesperetin and naringenin was investigated by analysing urine and plasma from 16 subjects after consumption of three treatments of orange juice...... epidemiological studies but the evidence is inconclusive. One major obstacle for epidemiological studies investigating associations between flavonoid intake and risk of CHD is the estimation of flavonoid intake. There is a vast variety of flavonoids in commonly eaten food products but only limited knowledge...... of their content. In addition, variation in individual metabolic genotype and microflora may greatly affect the actual flavonoid exposure. The preventive effects of flavonoids on CHD are mainly ascribed to their anti-inflammatory and antioxidant activities. Several mechanisms of anti-inflammatory and antioxidant...

  17. Potential Climatic Effects on the Greenland Ice Sheet

    Science.gov (United States)

    Bindschadler, R. A.

    1984-01-01

    The Greenland Ice Sheet covers an area of 1,720,000 sq. km and contains approximately 2,600,000 cu km of ice. Most of the ice sheet receives an excess of snow accumulation over the amount of ice lost to wind, meltwater run-off or other ablative processes. The majority of mass loss occurs at the margin of the ice sheet as either surface melt, which flows into the sea or calving of icebergs from the tongues of outlet glaciers. Many estimates of these processes were published. An average of five published estimates is summarized. If these estimates are correct, then the Greenland Ice Sheet is in approximate equilibrium and contributes 490 cu km/a of fresh water to the North Atlantic and Arctic Oceans. Climate effects, ice sheet flow, and application of remote sensing to tracking of the ice sheet are discussed.

  18. Potential health effects of greenhouse effect and ozone layer depletion in Australia.

    Science.gov (United States)

    Ewan, C; Bryant, E A; Calvert, G D; Marthick, J; Condon-Paoloni, D

    1991-04-15

    To identify potential health effects of the greenhouse effect and ozone layer depletion in Australia. Data were derived from a number of sources: (i) published articles accessed from relevant databases in the disciplines of health, public health and climatology over the past 20 years; (ii) published conference proceedings, review monographs and government reports covering the topic; (iii) a survey of experts in public health and climatology/geography (150 individuals were surveyed in the first phase with a 63% response rate); and (iv) a consensus conference in which 22 invited experts reviewed the results of the literature review and survey and a second conference in which 18 senior members of the health bureaucracy and public health profession considered the implications of the findings. Over 200 published articles or monographs were reviewed. Criteria for selection were whether the papers contributed information to the objectives of the review. Because of the nature of the problem under investigation, predictions based on reasonable scientific assumptions were the major content of the review rather than conclusions based on scientific research. The major predicted health effects of long-term climatic change in Australia are skin and eye damage from increased ultraviolet radiation exposure, increased incidence of some respiratory diseases, vector-borne and water-borne diseases, and the social and physical effects of natural hazards and social and economic restructuring. The most vulnerable groups include the aged, the very young, the chronically ill, those living in poorly designed neighbourhoods and those working in outdoor occupations or heavy industry. The potential effects on health of long-term climatic change cover the broad spectrum of public health concerns. Detailed predictions of likely problems in specific geographic areas are not yet possible, but progressive development of such predictive capability is a high priority. Doctors will have an

  19. Plant effects on soil denitrification - a review of potential mechanisms

    Science.gov (United States)

    Malique, Francois; Butterbach-Bahl, Klaus; Dannenmann, Michael

    2017-04-01

    Denitrification is a microbial process occurring in soils, both producing and consuming the potent greenhouse gas nitrous oxide (NO), competing for nitrate with plants and hydrological leaching pathways, removing nutrients and reactive nitrogen from the biosphere, and closing the global nitrogen cycle. Despite its obvious importance, denitrification remained among the least well quantified biogeochemical processes in soils. This is due to enormous methodological difficulties involved in the direct quantification of soil microbial denitrification rates (mainly with regard to the terminal product N2) and the denitrification nitrogen gas product ratios (NO:N2O:N2), Plants may affect denitrification through a myriad of mechanisms such as e.g., competition for nitrate and water, through oxygen consumption, by regulating litter quality and changing soil pH, and via the exudation of labile carbon or secondary plant compounds involved in shaping the rhizospheric microbial community. However, plant effects on denitrification so far hardly were quantified so that the actual extent of plant control on denitrification is largely unknown. Here, we summarize the current knowledge on mechanisms how plants can affect denitrification rates and N gas product ratios in soils at temporal scales from hours to days and years. We review earlier research to quantify plant effects on denitrification as well as critically discuss the limited methods currently available to quantify plant-soil-denitrifier interactions. Finally, we provide pointers to use plants as tools to manage denitrification, e.g. to improve N use efficiency in agricultural ecosystems and to minimize soil nitrous oxide emissions.

  20. Potentiation of the hypotensive effect of adrenomedullin in pregnant rats.

    Science.gov (United States)

    Makino, I; Shibata, K; Makino, Y; Kangawa, K; Kawarabayashi, T

    1999-12-03

    The hypotensive effect of adrenomedullin, a potent vasodilator peptide, was examined in conscious pregnant (6, 13 and 20 days of pregnancy) and non-pregnant rats. The intravenous administration of adrenomedullin (0.01-3.0 nmol/kg) produced a dose-dependent depressor response in pregnant and non-pregnant rats. At low doses (0.01-0.1 nmol/kg), the maximum decrease in blood pressure was significantly higher in pregnant rats (20 days pregnant) than in non-pregnant rats. At high doses, no significant difference was observed between the two groups. Furthermore, the administration of adrenomedullin did not significantly affect the basal mean blood pressure (MBP) at any dose when compared to the non-pregnant group at 6 and 13 days of pregnancy. In the ovariectomized rats, the depressor responses in 17beta-estradiol-treated, progesterone-treated and 17beta-estradiol+progesterone-treated rats were not significantly different from that in the control rats, suggesting that the augmented effect on the depressor response to adrenomedullin in pregnant rats may not be due to hormonal changes during pregnancy. The adrenomedullin receptor mRNA level of the descending thoracic aorta was significantly higher in the late-pregnancy rats (20 days of pregnancy). However, the levels did not show any difference between the early-pregnant rats (6 and 13 days of pregnancy) and the non-pregnant rats. These findings suggested that the changes in the depressor response to adrenomedullin which occur at term in pregnant rats may be mediated by changes of adrenomedullin receptor gene expression rather than by sex hormones.

  1. Tea polyphenols, their biological effects and potential molecular targets.

    Science.gov (United States)

    Chen, D; Milacic, V; Chen, M S; Wan, S B; Lam, W H; Huo, C; Landis-Piwowar, K R; Cui, Q C; Wali, A; Chan, T H; Dou, Q P

    2008-04-01

    Tea is the most popular beverage in the world, second only to water. Tea contains an infusion of the leaves from the Camellia sinensis plant rich in polyphenolic compounds known as catechins, the most abundant of which is (-)-EGCG. Although tea has been consumed for centuries, it has only recently been studied extensively as a health-promoting beverage that may act to prevent a number of chronic diseases and cancers. The results of several investigations indicate that green tea consumption may be of modest benefit in reducing the plasma concentration of cholesterol and preventing atherosclerosis. Additionally, the cancer-preventive effects of green tea are widely supported by results from epidemiological, cell culture, animal and clinical studies. In vitro cell culture studies show that tea polyphenols potently induce apoptotic cell death and cell cycle arrest in tumor cells but not in their normal cell counterparts. Green tea polyphenols were shown to affect several biological pathways, including growth factor-mediated pathway, the mitogen-activated protein (MAP) kinase-dependent pathway, and ubiquitin/proteasome degradation pathways. Various animal studies have revealed that treatment with green tea inhibits tumor incidence and multiplicity in different organ sites such as skin, lung, liver, stomach, mammary gland and colon. Recently, phase I and II clinical trials have been conducted to explore the anticancer effects of green tea in humans. A major challenge of cancer prevention is to integrate new molecular findings into clinical practice. Therefore, identification of more molecular targets and biomarkers for tea polyphenols is essential for improving the design of green tea trials and will greatly assist in a better understanding of the mechanisms underlying its anti-cancer activity.

  2. Olive Oil and its Potential Effects on Alzheimer's Disease

    Science.gov (United States)

    Antony, Shan; Zhang, G. P.

    Alzheimer's disease is a neuro-degenerative brain disease that is responsible for affecting the lives of hundreds of thousands of people every year. There has been no evidence to suggest a cure for the disease and the only existing treatments have very low rates of success in trial patients. This is largely due to the fact that the brain is one of the most undiscovered parts of the human body. Brain chemistry is highly complex and responds to its environment in random and radical ways. My research includes testing the reactionary outcomes of combining compounds of olive oil with the 20 basic amino acids. Regions around the world with olive oil based diets show a direct correlation to lower rates of Alzheimer's. Testing few compounds of olive oil with chemicals already found in the brain may yield to a better understanding as to why that is. I took the compounds tyrosol, hydroxytyrosol, and oleocanthal, and combined them with the 20 basic amino acids and calculated the total energy of the new molecule. The molecules produced with acceptably low energy values will be the center of further research. These molecules could lead to truly understanding olive oil's effect on the brain, and ultimately, the cure or prevention of Alzheimer's disease.

  3. An effective pair potential for liquid semiconductor, Se: Structure and related dynamical properties

    Indian Academy of Sciences (India)

    P P Nath; S Sarkar; R N Joarder

    2005-07-01

    The effective pair potential of liquid semiconductor Se is extracted from its experimental structure factor data using an accurate liquid state theory and this shows important basic features. A model potential incorporating the basic features of the structure factor extracted potential is suggested. This model potential is then used to describe through low-order perturbation theory, the structure and related dynamical properties like self-diffusion coefficient and shear viscosity of this complex liquid over a wide range of temperatures.

  4. High tides and rising seas: potential effects on estuarine waterbirds

    Science.gov (United States)

    Erwin, R.M.; Sanders, G.M.; Prosser, D.J.; Cahoon, D.R.; Greenberg, Russell; Maldonado, Jesus; Droege, Sam; McDonald, M.V.

    2006-01-01

    Coastal waterbirds are vulnerable to water-level changes especially under predictions of accelerating sea-level rise and increased storm frequency in the next century. Tidal and wind-driven fluctuations in water levels affecting marshes, their invertebrate communities, and their dependent waterbirds are manifested in daily, monthly, seasonal, annual, and supra-annual (e.g., decadal or 18.6-yr) periodicities. Superimposed on these cyclic patterns is a long-term (50?80 yr) increase in relative sea-level rise that varies from about 2?4 + mm/yr along the Atlantic coastline. At five study sites selected on marsh islands from Cape Cod, Massachusetts to coastal Virginia, we monitored marsh elevation changes and flooding, tide variations over time, and waterbird use. We found from longterm marsh core data that marsh elevations at three of five sites may not be sufficient to maintain pace with current sea-level rise. Results of the short-term (3?4 yr) measures using surface elevation tables suggest a more dramatic difference, with marsh elevation change at four of five sites falling below relative sea-level rise. In addition, we have found a significant increase (in three of four cases) in the rate of surface marsh flooding in New Jersey and Virginia over the past 70?80 yr during May?July when waterbirds are nesting on or near the marsh surface. Short-term, immediate effects of flooding will jeopardize annual fecundity of many species of concern to federal and state agencies, most notably American Black Duck (Anas rubripes), Nelson?s Sharp-tailed Sparrow (Ammodramus nelsoni), Saltmarsh Sharp-tailed Sparrow (A. caudacutus), Seaside Sparrow (A. maritima), Coastal Plain Swamp Sparrow (Melospiza georgiana nigrescens), Black Rail (Laterallus jamaicensis), Forster?s Tern (Sterna forsteri), Gull-billed Tern (S. nilotica), Black Skimmer (Rynchops niger), and American Oystercatcher (Haemotopus palliatus). Forster?s Terns are probably most at risk given the large proportion of their

  5. On the potential cost effectiveness of scientific audits.

    Science.gov (United States)

    Click, J L

    1989-09-01

    inefficient process for uncovering scientific fraud (5, 6, 9). Data from a survey of university scientists was also presented, indicating ". . . a reluctance to take prompt, corrective action not only when an investigator suspects another of misconduct but also should the investigator discover flaws in his or her own published reports-whether the flaws were the result of honest error or fraud"; (10). The uncritical acceptance by established scientists that the self-correcting process works compounds the problem. The Editor of Science has written that";. . . 99.9999 percent of reports are accurate and truthful. . ."; (8). If indeed only 0.0001% of published reports were inaccurate or untruthful, there would be little justification for scientific audits. However, congressional testimony from the National Institutes of Health (NIH) revealed that";. . . the NIH Director's office has handled an average of 15-20 allegations and reports of misconduct annually in its extramural programs, which supports the work of approximately 50,000 scientists"; (11). As I shall attempt to demonstrate, since NIH alone receives fraud-related complaints concerning the work of at least 0.03% of scientists it supports in other institutions, and since evidence indicates that the incidence of fraud is considerably greater than 0.03% (10, 12), the need to audit data is justifiable on the basis of being cost effective.

  6. Holographic Schwinger Effect in a Confining D3-Brane Background with Chemical Potential

    Directory of Open Access Journals (Sweden)

    Zi-qiang Zhang

    2016-01-01

    Full Text Available Using the AdS/CFT correspondence, we investigate the Schwinger effect in a confining D3-brane background with chemical potential. The potential between a test particle pair on the D3-brane in an external electric field is obtained. The critical field Ec in this case is calculated. Also, we apply numerical method to evaluate the production rate for various cases. The results imply that the presence of chemical potential tends to suppress the pair production effect.

  7. Effective attractive potential between identical dielectric molecules via Lifshitz theory

    Institute of Scientific and Technical Information of China (English)

    CHEN; Laiwen

    2001-01-01

    . Phys. Lett., 99, 84: 4.[26]Cársky, P., Selzle, H. L., Schlag, E. W., Ab initio calculations on the structure of the benzene dimer, Chem. Phys., 988, 25: 65.[27]Aggarwal, S. L., Physical constants of poly (ethylen), in Polymer Handbook (eds. Brandrup, J., Lmmergut, E. H.), 2nd., New York: John Wiley & Sons. 97V3—V22.[28]Suhai Sánder, Calculation of the mechanical and optical properties of polyethylene including electron correlation effects, in Quantum Chemistry of Polymers-Solid State Aspects (ed. Ladik, J.), Dordrechit: D. Redel Publishing Company, 984, 0—0.[29]Maitland, G. C., Rigby, M., Smith, E. B. Et al., Intermolecular Forces: Their Origin and Determination, Oxford: Clarendon Press, 98, 437—484.[30]Sumpter, B. G., Noid, D. W., Wunderlich, B., Computer experiments on the internal dynamics of crystalline polyethylene: mechanistic details of conformational disorder, J. Chem. Phys., 990, 93: 6875.[31]Martoňák, R., Paul, W., Binder, K., Orthorhombic phase of crystalline polyethylene: a constant pressure path-integral Monte Carlo study, Phys. Rev., 998, 57: 2425.

  8. Effect of a prenylamine analog (MG8926) on spontaneous action potentials in isolated rabbit sinoatrial node.

    Science.gov (United States)

    Nakanishi, H; Matsuoka, I; Ono, T; Yoshida, H; Uchibori, T; Kogi, K

    1996-12-01

    Effects of verapamil, prenylamine and a prenylamine analog, MG8926 on the intracellular spontaneous action potentials recorded from the isolated rabbit sinoatrial (SA) node were studied. Verapamil (1 microM), a selective inhibitor for slow Ca2+ channels, prolonged the cycle length, decreased the rate of diastolic depolarization, the rate of rise of action potential, the amplitude of action potential and the maximal diastolic potential, and usually arrested showing subthreshold fluctuation of the membrane potential within several ten min. Prenylamine (10 microM), a nonselective inhibitor for slow Ca2+ channels, tended to prolong the cycle length to decrease the diastolic depolarization, the rate of rise of action potential, the amplitude of action potential. However, these changes were statistically insignificant. Prenylamine at the concentration of 10 microM had no effect on the maximal diastolic potential. MG8926 (10 microM) prolonged the cycle length, decreased the rate of diastolic depolarization, the rate of rise of action potential and tended to decrease the amplitude of action potential. MG8926 at the concentration of 10 microM had almost no effect on the maximal diastolic potential. The present findings may indicate that replacement of phenyl residue of prenylamine by cyclohexyl residue increases the inhibitory action on the slow Ca2+ channels in rabbit SA node.

  9. Potential pulmonary effects of engineered carbon nanotubes: in vitro genotoxic effects.

    Science.gov (United States)

    Sargent, Linda M; Reynolds, Steven H; Castranova, Vincent

    2010-12-01

    The development of novel engineered nano-sized materials is a rapidly emerging technology with many applications in medicine and industry. In vitro and in vivo studies have suggested many deleterious effects of carbon nanotube exposure including granulomatous inflammation, release of cytosolic enzymes, pulmonary fibrosis, reactive oxygen damage, cellular atypia, DNA fragmentation, mutation and errors in chromosome number as well as mitotic spindle disruption. The physical properties of the carbon nanotubes make respiratory exposure to workers likely during the production or use of commercial products. Many of the investigations of the genotoxicity of carbon nanotubes have focused on reactive oxygen mediated DNA damage; however, the long thin tubular-shaped carbon nanotubes have a striking similarity to cellular microtubules. The similarity of carbon nanotubes to microtubules suggests a potential to interact with cellular biomolecules, such as the mitotic spindle, as well as the motor proteins that separate the chromosomes during cell division. Disruption of centrosomes and mitotic spindles would result in monopolar, tripolar, and quadrapolar divisions of chromosomes. The resulting aneuploidy is a key mechanism in the potential carcinogenicity of carbon nanotubes.

  10. Towards the prevention of potential aluminum toxic effects and an effective treatment for Alzheimer's disease.

    Science.gov (United States)

    Percy, Maire E; Kruck, Theo P A; Pogue, Aileen I; Lukiw, Walter J

    2011-11-01

    In 1991, treatment with low dose intramuscular desferrioxamine (DFO), a trivalent chelator that can remove excessive iron and/or aluminum from the body, was reported to slow the progression of Alzheimer's disease (AD) by a factor of two. Twenty years later this promising trial has not been followed up and why this treatment worked still is not clear. In this critical interdisciplinary review, we provide an overview of the complexities of AD and involvement of metal ions, and revisit the neglected DFO trial. We discuss research done by us and others that is helping to explain involvement of metal ion catalyzed production of reactive oxygen species in the pathogenesis of AD, and emerging strategies for inhibition of metal-ion toxicity. Highlighted are insights to be considered in the quests to prevent potentially toxic effects of aluminum toxicity and prevention and intervention in AD.

  11. Effective Potential of a Two-State Model for Molecular Motor

    Institute of Scientific and Technical Information of China (English)

    HAN Ying-Rong; ZHAO Tong-Jun; ZHAN-Yong; YAN Wei-Li

    2005-01-01

    We study force generation and motion of molecular motors using a simple two-state model in the paper.Asymmetric and periodic potential is adopted to describe the interaction between motor proteins and filaments that are periodic and polar. The current and the slope of the effective potential as functions of the temperature and transition rates are calculated in the two-state model. The ratio of the slope of the effective potential to the current is also calculated. It is shown that the directed motion of motor proteins is relevant to the effective potential. The slope of the effective potential corresponds to an average force. The non-vanishing force therefore implies that detailed balance is broken in the process of transition between different states.

  12. A systematic review of intervention effects on potential mediators of children’s physical activity

    Directory of Open Access Journals (Sweden)

    Brown Helen

    2013-02-01

    Full Text Available Abstract Background Many interventions aiming to increase children’s physical activity have been developed and implemented in a variety of settings, and these interventions have previously been reviewed; however the focus of these reviews tends to be on the intervention effects on physical activity outcomes without consideration of the reasons and pathways leading to intervention success or otherwise. To systematically review the efficacy of physical activity interventions targeting 5-12 year old children on potential mediators and, where possible, to calculate the size of the intervention effect on the potential mediator. Methods A systematic search identified intervention studies that reported outcomes on potential mediators of physical activity among 5-12 year old children. Original research articles published between 1985 and April 2012 were reviewed. Results Eighteen potential mediators were identified from 31 studies. Positive effects on cognitive/psychological potential mediators were reported in 15 out of 31 studies. Positive effects on social environmental potential mediators were reported in three out of seven studies, and no effects on the physical environment were reported. Although no studies were identified that performed a mediating analysis, 33 positive intervention effects were found on targeted potential mediators (with effect sizes ranging from small to large and 73% of the time a positive effect on the physical activity outcome was reported. Conclusions Many studies have reported null intervention effects on potential mediators of children’s physical activity; however, it is important that intervention studies statistically examine the mediating effects of interventions so the most effective strategies can be implemented in future programs.

  13. Vortex lattice mobility and effective pinning potentials in the peak effect region in YBCO crystals

    Indian Academy of Sciences (India)

    G Pasquini; V Bekeris

    2006-01-01

    The peak effect (PE) in the critical current density in both low and high temperature superconductors has been the subject of a large amount of experimental and theoretical work in the last few/several years. In the case of YBCO, crucial discussions describing a dynamic or a static picture are not settled. In that region of field and temperature the mobility of the vortex lattice (VL) is found to be dependent on the dynamical history. Recently we reported evidence that the VL reorganizes and accesses to robust VL configurations (VLCs) with different effective pinning potential wells arising in response to different system histories. One of the keys to understand the nature of the PE is to investigate the VL behavior in the vicinity of the various VLCs in the region of the PE. The stability of these VLCs was investigated and it was found that they have distinct characteristic relaxation times, which may be related to elastic or plastic creep processes. In this paper we review some of these results and propose a scenario to describe the PE in YBCO crystals.

  14. The ion potential in warm dense matter: wake effects due to streaming degenerate electrons

    CERN Document Server

    Moldabekov, Zhandos; Bonitz, Michael; Ramazano, Tlekkabul

    2014-01-01

    The effective dynamically screened potential of a classical ion in a stationary flowing quantum plasma at finite temperature is investigated. This is a key quantity for thermodynamics and transport of dense plasmas in the warm dense matter regime. To compute this potential a linear response description of the electrons via the Mermin dielectric function is utilized with electron-electron collisions taken into account via a relaxation time approximation. The ion potential strongly deviates from the static Yukawa potential exhibiting the familiar oscillatory structure with attractive minima (wake potential). This potential is analyzed in detail for high-density plasmas with values of the Brueckner parameter in the range $0.1 \\le r_s \\le 1$, for a broad range of plasma temperature and electron streaming velocity. It is shown that wake effects become weaker with increasing temperature of the electrons. Finally, we obtain the minimal electron streaming velocity for which attraction between ions occurs. This veloci...

  15. Effects of nitrogen ion implantation on Ca2+ concentration and membrane potential of pollen cell

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The effects of low energy nitrogen ion implantation on Ca2+ concentration and membrane potential of lily (lilium davidii Duch) pollen cell have been studied. The results showed that the Ca2+ concentration was increased when pollen grain was implanted by nitrogen ion with energy 100keV and dose 1013 ions/cra2. However, the increase of Ca2+ concentration was partly inhibited by the addition of Ca2+channel inhibitor depending on dose. And nitrogen ion implantation caused depolarization of pollen cell membrane potential. In other words, membrane potential was increased,but the effect decreased by adding Ca2+ channel inhibitor.However, it was still significantly higher than the membrane potential of control cells. It was indicated that the depolarization of cell membrane potential opened the calcium channel on the membrane that caused the increasing of intraceilular calcium concentration. This might be an earlier step of the effect of low energy nitrogen ion implantation on pollen germination.

  16. The Effectiveness of Positive Coping Program on Reduction of Addiction Potential in Students

    OpenAIRE

    Fatemeh Nematollahi; Mahmoud Golzari; Jamal Shams

    2010-01-01

    Objective: This study aimed to study the effectiveness of positive coping program on reduction of addiction potential in dormitory girl students. Method: The research method was semi experimental method namely: pre test-post test with witness group. In selection of sample, first addiction potential scale administered among 160 dormitory girl students, and 20 of them who were scored higher than cutoff score on addiction potential scale selected and divided to two experimental and witness group...

  17. Potential impacts on groundwater resources of deep CO2 storage: natural analogues for assessing potential chemical effects

    Science.gov (United States)

    Lions, J.; Gale, I.; May, F.; Nygaard, E.; Ruetters, H.; Beaubien, S.; Sohrabi, M.; Hatzignatiou, D. G.; CO2GeoNet Members involved in the present study Team

    2011-12-01

    Carbon dioxide Capture and Storage (CCS) is considered as one of the promising options for reducing atmospheric emissions of CO2 related to human activities. One of the main concerns associated with the geological storage of CO2 is that the CO2 may leak from the intended storage formation, migrate to the near-surface environment and, eventually, escape from the ground. This is a concern because such leakage may affect aquifers overlying the storage site and containing freshwater that may be used for drinking, industry and agriculture. The IEA Greenhouse Gas R&D Programme (IEAGHG) recently commissioned the CO2GeoNet Association to undertake a review of published and unpublished literature on this topic with the aim of summarizing 'state of the art' knowledge and identifying knowledge gaps and research priorities in this field. Work carried out by various CO2GeoNet members was also used in this study. This study identifies possible areas of conflict by combining available datasets to map the global and regional superposition of deep saline formations (DSF) suitable for CO2 storage and overlying fresh groundwater resources. A scenario classification is developed for the various geological settings where conflict could occur. The study proposes two approaches to address the potential impact mechanisms of CO2 storage projects on the hydrodynamics and chemistry of shallow groundwater. The first classifies and synthesizes changes of water quality observed in natural/industrial analogues and in laboratory experiments. The second reviews hydrodynamic and geochemical models, including coupled multiphase flow and reactive transport. Various models are discussed in terms of their advantages and limitations, with conclusions on possible impacts on groundwater resources. Possible mitigation options to stop or control CO2 leakage are assessed. The effect of CO2 pressure in the host DSF and the potential effects on shallow aquifers are also examined. The study provides a review of

  18. Chemical Potential Dependence of the Dressed-Quark Propagator from an Effective Quark-Quark Interaction

    Institute of Scientific and Technical Information of China (English)

    ZONG Hong-Shi; PING Jia-Lun; SUN Wei-Min; CHANG Chao-Hsi; WANG Fan

    2002-01-01

    We exhibit a method for obtaining the low chemical potential dependence of the dressed quark propagatorfrom an effective quark-quark interaction model. Within this approach we explore the chemical potential dependenceof the dressed-quark propagator, which provides a means of determining the behavior of the chiral and deconfinementorder parameters. A comparison with the results of previous researches is given.

  19. The role of orbital products in the optimized effective potential method

    NARCIS (Netherlands)

    Kollmar, Christian; Filatov, Michael

    2008-01-01

    The orbital products of occupied and virtual orbitals are employed as an expansion basis for the charge density generating the local potential in the optimized effective potential method thus avoiding the use of auxiliary basis sets. The high computational cost arising from the quadratic increase of

  20. The effects of saliva on the erosive potential of three different wines

    NARCIS (Netherlands)

    Brand, H.S.; Tjoe Fat, G.M.; Veerman, E.C.I.

    2009-01-01

    Background:  The erosive potential of wine on teeth may be modified by the buffering capacity of saliva. This potential effect was studied for three different wines in vitro and in vivo. Methods:  The buffering capacity was studied in vitro by stepwise addition of small volumes of a dry white wine,

  1. Dynamical properties of non-ideal plasma on the basis of effective potentials

    Energy Technology Data Exchange (ETDEWEB)

    Ramazanov, T. S.; Kodanova, S. K.; Moldabekov, Zh. A.; Issanova, M. K. [IETP, Al-Farabi Kazakh National University, 71 Al-Farabi str., Almaty 050040 (Kazakhstan)

    2013-11-15

    In this work, stopping power has been calculated on the basis of the Coulomb logarithm using the effective potentials. Calculations of the Coulomb logarithm and stopping power for different interaction potentials and degrees of ionization are compared. The comparison with the data of other theoretical and experimental works was carried out.

  2. Superfield Effective Potential for the Supersymmetric Topologically Massive Gauge theory in Four Dimensions

    CERN Document Server

    Gama, F S; Nascimento, J R; Petrov, A Yu; da Silva, A J

    2015-01-01

    We explicitly calculate the one-loop effective potential for the supersymmetric topologically massive gauge theory in four dimensions, where the chiral scalar superfield is directly coupled to the field strength for the gauge spinor superfield.

  3. 76 FR 21368 - Evaluation of the Potential Developmental Effects of Cancer Chemotherapy During Pregnancy: Call...

    Science.gov (United States)

    2011-04-15

    ... Pregnancy: Call for Information and Nomination of Scientific Experts AGENCY: National Institute of... scientific evidence regarding the potential developmental effects of cancer chemotherapy during pregnancy... pregnancy outcomes and long- term health of offspring exposed to cancer chemotherapy agents during...

  4. On the tunneling time of arbitrary continuous potentials and the Hartman effect

    Institute of Scientific and Technical Information of China (English)

    Yin Cheng; Wu Zhi-Jing; Wang Xian-Ping; Sun Jing-Jing; Cao Zhuang-Qi

    2010-01-01

    This paper obtains a generalized tunneling time of one-dimensional potentials via time reversal invariance. It also proposes a simple explanation for the Hartman effect using the useful concept of the scattered subwaves.

  5. 76 FR 51034 - Availability of Draft NTP Monograph on Potential Developmental Effects of Cancer Chemotherapy...

    Science.gov (United States)

    2011-08-17

    ... HUMAN SERVICES Availability of Draft NTP Monograph on Potential Developmental Effects of Cancer... Monograph AGENCY: Division of the National Toxicology Program (DNTP), National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health. ACTION: Availability of Draft Monograph; Request...

  6. Quantum Nuclear Extension of Electron Nuclear Dynamics on Folded Effective-Potential Surfaces

    DEFF Research Database (Denmark)

    Hall, B.; Deumens, E.; Ohrn, Y.;

    2014-01-01

    A perennial problem in quantum scattering calculations is accurate theoretical treatment of low energy collisions. We propose a method of extracting a folded, nonadiabatic, effective potential energy surface from electron nuclear dynamics (END) trajectories; we then perform nuclear wave packet...

  7. Combined effect of bond and potential disorder in half-doped manganites.

    Science.gov (United States)

    Kumar, Sanjeev; Kampf, Arno P

    2008-02-22

    We analyze the effects of both bond and potential disorder in the vicinity of a first-order metal insulator transition in a two-band model for manganites using a real-space Monte Carlo method. Our results reveal a novel charge-ordered state coexisting with spin-glass behavior. We provide the basis for understanding the phase diagrams of half-doped manganites, and contrast the effects of bond and potential disorder and the combination of both.

  8. The effective potential of composite fields in weakly coupled QED in a uniform external magnetic field

    CERN Document Server

    Lee, D S; Ng, Y J; Shovkovy, I A

    1999-01-01

    The effective potential for the composite fields responsible for chiral symmetry breaking in weakly coupled QED in a magnetic field is derived. The global minimum of the effective potential is found to acquire a non-vanishing expectation value of the composite fields that leads to generating the dynamical fermion mass by an external magnetic field. The results are compared with those for the Nambu-Jona-Lasinio model.

  9. The Effect of Hydrocarbon Contamination on the Volta Potential of Second Phase Particles in Beryllium

    OpenAIRE

    Mallinson, Christopher; Watts, John

    2016-01-01

    The effect on the Volta potential, measured from second phase particles in beryllium, by the thin layer of hydrocarbon contamination pyrolised onto the surface under the action of an electron beam during secondary electron imaging has been investigated. Despite being only a few nanometres thick, this contamination has a significant influence on the Volta potential of second phase particles of interest. This work shows that such contamination can have a substantial effect on the measured poten...

  10. Effects of La3+ on H+ Transmembrane Gradient and Membrane Potential in Rice Seedling Roots

    Institute of Scientific and Technical Information of China (English)

    郑海雷; 张春光; 赵中秋; 马建华; 李利

    2002-01-01

    The effects of LaCl3 on membrane potential and transmembrane proton gradient for rice (Oryza sativa) seedling roots were studied. Highly purified plasma membrane was isolated by aqueous two-phase partitioning method. Both the gradient of transmembrane proton and membrane potential were stimulated by certain low concentration of LaCl3 and depressed by high concentration of LaCl3. The optimal concentration of La3+ is around 40~60 μmolL-1 for transmembrane proton gradient and membrane potential. It shows that La3+ can influence the generations and maintenances of membrane potential and transmembrane proton gradient in rice seedling roots.

  11. Post-Gaussian Effective Potential of Double sine-Gordon Field

    Institute of Scientific and Technical Information of China (English)

    CAI Wei-Ran; LOU Sen-Yue

    2005-01-01

    In the framework of the functional integral formalism, we calculate the effective potential of the double sine-Gordon (DsG) model up to the second order with an optimized expansion and the Coleman's normal-ordering prescription. Within the range of convergence, we make a comparison among the classicaland the effective potential of the first and second order. The numerical analysis shows that the DsG post-Gaussian EP possesses some fine global properties and makes a substantial and a concordant quantum correction to the features of the classical potential.

  12. Effects of angular dependent terms in the interatomic potential on defect properties in TiAl

    Energy Technology Data Exchange (ETDEWEB)

    Panova, J.; Farkas, D. [Virginia Polytechnic Inst., Blacksburg, VA (United States). Dept. of Materials Science and Engineering

    1995-08-01

    Interatomic potentials of the Embedded Atom and Embedded Defect types were used to study the effect of the angular dependent term in the Embedded Defect potential on the properties of defects in TiAl. The defect properties were computed with interatomic potentials developed with and without angular dependent terms. It was found that the inclusion of the angular dependent terms tends to increase the energies of the APB`s and lower the energies of stacking faults. The effects of the angular term on the relaxation around vacancies and antisites in TiAl was also studied, as well as the core structure of several dislocations in this compound.

  13. The Effective Kahler Potential, Metastable Vacua and R-Symmetry Breaking in O'Raifeartaigh Models

    CERN Document Server

    Benjamin, Shermane; Kain, Ben

    2010-01-01

    Much has been learned about metastable vacua and R-symmetry breaking in O'Raifeartaigh models. Such work has largely been done from the perspective of the superpotential and by including Coleman-Weinberg corrections to the scalar potential. Instead, we consider these ideas from the perspective of the one loop effective Kahler potential. We translate known ideas to this framework and construct convenient formulas for computing individual terms in the expanded effective Kahler potential. We do so for arbitrary R-charge assignments and allow for small R-symmetry violating terms so that both spontaneous and explicit R-symmetry breaking is allowed in our analysis.

  14. Comparative effectiveness research and big data: balancing potential with legal and ethical considerations.

    Science.gov (United States)

    Gray, Elizabeth Alexandra; Thorpe, Jane Hyatt

    2015-01-01

    Big data holds big potential for comparative effectiveness research. The ability to quickly synthesize and use vast amounts of health data to compare medical interventions across settings of care, patient populations, payers and time will greatly inform efforts to improve quality, reduce costs and deliver more patient-centered care. However, the use of big data raises significant legal and ethical issues that may present barriers or limitations to the full potential of big data. This paper addresses the scope of some of these legal and ethical issues and how they may be managed effectively to fully realize the potential of big data.

  15. Determination of Kohn-Sham effective potentials from electron densities using the differential virial theorem.

    Science.gov (United States)

    Ryabinkin, Ilya G; Staroverov, Viktor N

    2012-10-28

    We present an accurate method for constructing the Kohn-Sham effective potential corresponding to a given electron density in one-dimensional and spherically symmetric systems. The method is based on the differential virial theorem--an exact relation between the effective potential, the electron density, and the kinetic energy density. A distinctive feature of the proposed technique is that it employs a size-consistent bosonic reference potential to ensure the correct asymptotic behavior of the resulting Kohn-Sham potential. We describe a practical implementation of our method and use it to obtain high-quality exchange-correlation and correlation potentials of the neon and argon atoms from ab initio densities generated in large Slater- and Gaussian-type basis sets.

  16. Potential adverse effects of omega-3 Fatty acids in dogs and cats.

    Science.gov (United States)

    Lenox, C E; Bauer, J E

    2013-01-01

    Fish oil omega-3 fatty acids, mainly eicosapentaenoic acid and docosahexaenoic acid, are used in the management of several diseases in companion animal medicine, many of which are inflammatory in nature. This review describes metabolic differences among omega-3 fatty acids and outlines potential adverse effects that may occur with their supplementation in dogs and cats with a special focus on omega-3 fatty acids from fish oil. Important potential adverse effects of omega-3 fatty acid supplementation include altered platelet function, gastrointestinal adverse effects, detrimental effects on wound healing, lipid peroxidation, potential for nutrient excess and toxin exposure, weight gain, altered immune function, effects on glycemic control and insulin sensitivity, and nutrient-drug interactions.

  17. Scalar potential from de Sitter brane in 5D and effective cosmological constant

    CERN Document Server

    Ito, M

    2004-01-01

    We derive the scalar potential in zero mode effective action arising from a de Sitter brane embedded in five dimensions with bulk cosmological constant $\\Lambda$. The scalar potential for a scalar field canonically normalized is given by the sum of exponential potentials. In the case of $\\Lambda=0$ and $\\Lambda>0$, we point out that the scalar potential has a unstable local maximum at the origin and exponentially vanishes for large positive scalar field. In the case of $\\Lambda<0$, the scalar potential has a unstable local maximum at the origin and a stable local minimum, it is shown that the positive cosmological constant in brane is reduced by negative potential energy of scalar at minimum.

  18. Benzodiazepines have no effect on fear-potentiated startle in humans.

    Science.gov (United States)

    Baas, Johanna M P; Grillon, Christian; Böcker, Koen B E; Brack, Anouk A; Morgan, Charles A; Kenemans, J Leon; Verbaten, Marinus N

    2002-05-01

    Pre-clinical and clinical investigations have provided a great deal of evidence that the fear-potentiated startle paradigm represents a valid model for the objective assessment of emotional states of anxiety and fear. The four studies presented in this report sought to further validate the "threat of shock" paradigm as a human analogue to fear-potentiated startle in rats, by examining the effect of benzodiazepine administration on both baseline and fear-potentiated startle. Three studies, conducted at Utrecht University, evaluated the effects of oxazepam and of diazepam on baseline and fear-potentiated startle, whereas a fourth study, conducted at Yale University, evaluated the effect of diazepam on baseline, contextual and cue-specific fear-potentiated startle. The threat of shock paradigm consisted of verbal instruction about two visual cues (the threat cue predicted the possible administration of electric shock, the other predicted a safe period), followed by a series of presentations of these cues. During these conditions, acoustic startle stimuli were presented in order to elicit startle responses. The magnitude of the startle response was used to index the degree of fear or alarm experienced during the periods of threat and safety. The fourth study examined the effect of IV administration of diazepam in a similar threat of shock paradigm except that there were two additional context manipulations: electrode placement and darkness. None of the drug manipulations affected specific threat-cue potentiation of startle. However, reductions in baseline startle were observed. Further, startle potentiation by darkness was inhibited by diazepam. At least one type of fear-potentiated startle, i.e. potentiation by a cue-specific fear manipulation, is not susceptible to benzodiazepine treatment. In contrast, effects of manipulations more akin to anxiety (darkness, context) appear sensitive to benzodiazepines. Human experimental models differentiating between these cue

  19. Effects of carnosine on the evoked potentials in hippocampal CA1 region

    Institute of Scientific and Technical Information of China (English)

    Zhou-yan FENG; Xiao-jing ZHENG; Jing WANG

    2009-01-01

    Objective: To directly examine the effects of carnosine on neuronal excitation and inhibition in rat hippocampus in vivo. Methods: Artificial cerebrospinal fluid with carnosine was directly administrated over the exposed rat hippocampus. The changes of neuron activity in the CA1 region of hippocampus were evaluated by orthodromically- and antidromically-evoked potentials, as well as paired-pulse stimulation paradigm. Results: In both orthodromic and antidromic response potentials, carnosine transformed population spikes (PSs) with single spike into epileptiform multiple spikes. In addition, similar to the effect of γ-aminobutyric acidA (GABAA) antagonist picrotoxin, carnosine decreased paired-pulse stimulating depression significantly.However, no significant change was observed in the spontaneous field potentials during the application of carnosine. Conclusion:The results indicate a disinhibition-induced excitation effect of carnosine on the CA1 pyramidal neurons. It provides important information against the application of carnosine as a potential anticonvulsant in clinical treatment.

  20. Dissipative particle dynamics with an effective pair potential from integral equation theory of molecular liquids.

    Science.gov (United States)

    Kobryn, Alexander E; Nikolić, Dragan; Lyubimova, Olga; Gusarov, Sergey; Kovalenko, Andriy

    2014-10-16

    We present a method of DPD simulation based on a coarse-grained effective pair potential obtained from the DRISM-KH molecular theory of solvation. The theory is first used to calculate the radial distribution functions of all-atom solute monomers in all-atom solvent and then to invert them into an effective pair potential between coarse-grained beads such that their fluid without solvent accounts for molecular specificities and solvation effects in the all-atom system. Bonded interactions are sampled in relatively short MD of the all-atom system and modeled with best multi-Gaussian fit. Replacing the heuristically defined conservative force potential in DPD, the coarse-grained effective pair potential is free from the artificial restrictions on potential range and shape and on equal volume of solute and solvent blobs inherent in standard DPD. The procedure is flexible in specifying coarse-grained mapping and enormously increases computational efficiency by eliminating solvent. The method is validated on polystyrene chains of various length in toluene at finite concentrations for room and polystyrene glass transition temperature. It yields the chain elastic properties and diffusion coefficient in good agreement with experiment and all-atom MD simulations. DPD with coarse-grained effective pair potential is capable of predicting both structural and dynamic properties of polymer solutions and soft matter with high accuracy and computational efficiency.

  1. Repetitive transcranial magnetic stimulation decreases the kindling induced synaptic potentiation: effects of frequency and coil shape.

    Science.gov (United States)

    Yadollahpour, Ali; Firouzabadi, Seyed Mohammad; Shahpari, Marzieh; Mirnajafi-Zadeh, Javad

    2014-02-01

    The present study was aimed to investigate the effects of repetitive transcranial magnetic stimulation (rTMS) on kindling-induced synaptic potentiation and to study the effect of frequency and coil shape on rTMS effectiveness. Seizures were induced in rats by perforant path stimulation in a rapid kindling manner (12 stimulations/day). rTMS was applied at different frequencies (0.5, 1 and 2 Hz), using either figure-8 shaped or circular coils at different times (during or before kindling stimulations). rTMS had antiepileptogenic effect at all frequencies and imposed inhibitory effects on enhancement of population excitatory postsynaptic potential slope and population spike amplitude when applied during kindling acquisition. Furthermore, it prevented the kindling-induced changes in paired pulse indices. The inhibitory effect of rTMS was higher at the frequency of 1 Hz compared to 0.5 and 2 Hz. Application of rTMS 1Hz by circular coil imposed a weaker inhibitory action compared with the figure-8 coil. In addition, the results showed that pretreatment of animals by both coils had similar preventing effect on kindling acquisition as well as kindling-induced synaptic potentiation. Obtained results demonstrated that the antiepileptogenic effect of low frequency rTMS is accompanied with the preventing of the kindling induced potentiation. This effect is dependent on rTMS frequency and slightly on coil-type.

  2. Differential effects of K(+) channel blockers on frequency-dependent action potential broadening in supraoptic neurons.

    Science.gov (United States)

    Hlubek, M D; Cobbett, P

    2000-09-15

    Recordings were made from magnocellular neuroendocrine cells dissociated from the supraoptic nucleus of the adult guinea pig to determine the role of voltage gated K(+) channels in controlling the duration of action potentials and in mediating frequency-dependent action potential broadening exhibited by these neurons. The K(+) channel blockers charybdotoxin (ChTx), tetraethylammonium (TEA), and 4-aminopyridine (4-AP) increased the duration of individual action potentials indicating that multiple types of K(+) channel are important in controlling action potential duration. The effect of these K(+) channel blockers was almost completely reversed by simultaneous blockade of voltage gated Ca(2+) channels with Cd(2+). Frequency-dependent action potential broadening was exhibited by these neurons during trains of action potentials elicited by membrane depolarizing current pulses presented at 10 Hz but not at 1 Hz. 4-AP but not ChTx or TEA inhibited frequency-dependent action potential broadening indicating that frequency-dependent action potential broadening is dependent on increasing steady-state inactivation of A-type K(+) channels (which are blocked by 4-AP). A model of differential contributions of voltage gated K(+) channels and voltage gated Ca(2+) channels to frequency-dependent action potential broadening, in which an increase of Ca(2+) current during each successive action potential is permitted as a result of the increasing steady-state inactivation of A-type K(+) channels, is presented.

  3. Electroviscous effect on fluid drag in a microchannel with large zeta potential.

    Science.gov (United States)

    Jing, Dalei; Bhushan, Bharat

    2015-01-01

    The electroviscous effect has been widely studied to investigate the effect of surface charge-induced electric double layers (EDL) on the pressure-driven flow in a micro/nano channel. EDL has been reported to reduce the velocity of fluid flow and increase the fluid drag. Nevertheless, the study on the combined effect of EDL with large zeta potential up to several hundred millivolts and surface charge depenedent-slip on the micro/nano flow is still needed. In this paper, the nonlinear Poisson-Boltzmann equation for electrical potential and ion distribution in non-overlapping EDL is first analytically solved. Then, the modified Navier-Stokes equation for the flow considering the effect of surface charge on the electrical conductivity of the electrolyte and slip length is analytically solved. This analysis is used to study the effect of non-overlapping EDL with large zeta potential on the pressure-driven flow in a microchannel with no-slip and charge-dependent slip conditions. The results show that the EDL leads to an increase in the fluid drag, but that slip can reduce the fluid drag. When the zeta potential is large enough, the electroviscous effect disappears for flow in the microchannel under a no-slip condition. However, the retardation of EDL on the flow and the enhancement of slip on the flow counteract each other under a slip condition. The underlying mechanisms of the effect of EDL with large zeta potential on fluid drag are the high net ionic concentration near the channel wall and the fast decay of electrical potential in the EDL when the zeta potential is large enough.

  4. Effect of Glucuronidation on the Potential of Kaempferol to Inhibit Serine/Threonine Protein Kinases

    NARCIS (Netherlands)

    Beekmann, Karsten; Haan, De Laura H.J.; Actis-Goretta, Lucas; Bladeren, Van Peter J.; Rietjens, Ivonne M.C.M.

    2016-01-01

    To study the effect of metabolic conjugation of flavonoids on the potential to inhibit protein kinase activity, the inhibitory effects of the dietary flavonol kaempferol and its major plasma conjugate kaempferol-3-O-glucuronide on protein kinases were studied. To this end, the inhibition of the p

  5. Removing the gauge parameter dependence of the effective potential by a field redefinition

    DEFF Research Database (Denmark)

    Nielsen, N. K.

    2014-01-01

    The gauge parameter dependence of the effective potential is determined by partial differential equations involving also the Higgs boson field expectation value. Solving these equations by the method of characteristics leads to elimination of the gauge parameter dependence of the effective...

  6. Differential effects of thioridazine enantiomers on action potential duration in rabbit papillary muscle

    DEFF Research Database (Denmark)

    Jensen, A. S.; Pennisi, C. P.; Sevcencu, C.;

    2015-01-01

    with (+)-thioridazine. In this study we for the first time investigate the cardiotoxicity of the isolated thioridazine enantiomers and show their effects on ventricular repolarization. The effects of (+)-thioridazine, (-)-thioridazine, and racemate on the rabbit ventricular action potential duration (APD) were...... investigated in a randomized controlled blinded experiment. Action potentials were measured in papillary muscles isolated from 21 female rabbits, and the drug effect on 90% APD in comparison with control (DeltaDelta-APD90) was evaluated. Increasing concentrations of (+)-thioridazine and the racemate caused...

  7. Factors predictive of stress, organizational effectiveness, and coronary heart disease potential.

    Science.gov (United States)

    Hendrix, W H

    1985-07-01

    Research to predict stress, organizational effectiveness, and potential for developing coronary heart disease (CHD) is presented based on two samples (n = 357 and n = 225). Results indicate that perceived stress is predicted by a combination of individual and job related characteristics. The data suggest that stress, in turn, affects individual and organizational health and effectiveness, by causing increases in cold/flu episodes, somatic symptoms, while decreasing job satisfaction. In addition, stress has an indirect effect on job performance and absenteeism. Models for predicting the ratio of total serum cholesterol divided by HDL cholesterol as an indicator of coronary heart disease potential are provided and a CHD screening model is proposed.

  8. Influence of interface potential on the effective mass in Ge nanostructures

    Energy Technology Data Exchange (ETDEWEB)

    Barbagiovanni, E. G., E-mail: eric.barbagiovanni@ct.infn.it; Cosentino, S.; Terrasi, A.; Mirabella, S. [MATIS IMM-CNR and Dipartimento di Fisica e Astronomia, Università di Catania, via S. Sofia 64, 95123 Catania (Italy); Lockwood, D. J. [Measurement Science and Standards, National Research Council, Ottawa, Ontario K1A 0R6 (Canada); Costa Filho, R. N. [Departamento de Física, Universidade Federal do Ceará, Caixa Postal 6030, Campus do Pici, 60455-760 Fortaleza, Ceará (Brazil)

    2015-04-21

    The role of the interface potential on the effective mass of charge carriers is elucidated in this work. We develop a new theoretical formalism using a spatially dependent effective mass that is related to the magnitude of the interface potential. Using this formalism, we studied Ge quantum dots (QDs) formed by plasma enhanced chemical vapour deposition (PECVD) and co-sputtering (sputter). These samples allowed us to isolate important consequences arising from differences in the interface potential. We found that for a higher interface potential, as in the case of PECVD QDs, there is a larger reduction in the effective mass, which increases the confinement energy with respect to the sputter sample. We further understood the action of O interface states by comparing our results with Ge QDs grown by molecular beam epitaxy. It is found that the O states can suppress the influence of the interface potential. From our theoretical formalism, we determine the length scale over which the interface potential influences the effective mass.

  9. The Effects of Puerarin on Rat Ventricular Myocytes and the Potential Mechanism

    Science.gov (United States)

    Xu, Hao; Zhao, Manxi; Liang, Shenghui; Huang, Quanshu; Xiao, Yunchuan; Ye, Liang; Wang, Qinyi; He, Longmei; Ma, Lanxiang; Zhang, Hua; Zhang, Li; Jiang, Hui; Ke, Xiao; Gu, Yuchun

    2016-01-01

    Puerarin, a known isoflavone, is commonly found as a Chinese herb medicine. It is widely used in China to treat cardiac diseases such as angina, cardiac infarction and arrhythmia. However, its cardioprotective mechanism remains unclear. In this study, puerarin significantly prolonged ventricular action potential duration (APD) with a dosage dependent manner in the micromolar range on isolated rat ventricular myocytes. However, submicromolar puerarin had no effect on resting membrane potential (RMP), action potential amplitude (APA) and maximal velocity of depolarization (Vmax) of action potential. Only above the concentration of 10 mM, puerarin exhibited more aggressive effect on action potential, and shifted RMP to the positive direction. Millimolar concentrations of puerarin significantly inhibited inward rectified K+ channels in a dosage dependent manner, and exhibited bigger effects upon Kir2.1 vs Kir2.3 in transfected HEK293 cells. As low as micromolar range concentrations of puerarin significantly inhibited Kv7.1 and IKs. These inhibitory effects may due to the direct inhibition of puerarin upon channels not via the PKA-dependent pathway. These results provided direct preclinical evidence that puerarin prolonged APD via its inhibitory effect upon Kv7.1 and IKs, contributing to a better understanding the mechanism of puerarin cardioprotection in the treatment of cardiovascular diseases. PMID:27762288

  10. Ion potential in warm dense matter: wake effects due to streaming degenerate electrons.

    Science.gov (United States)

    Moldabekov, Zhandos; Ludwig, Patrick; Bonitz, Michael; Ramazanov, Tlekkabul

    2015-02-01

    The effective dynamically screened potential of a classical ion in a stationary flowing quantum plasma at finite temperature is investigated. This is a key quantity for thermodynamics and transport of dense plasmas in the warm-dense-matter regime. This potential has been studied before within hydrodynamic approaches or based on the zero temperature Lindhard dielectric function. Here we extend the kinetic analysis by including the effects of finite temperature and of collisions based on the Mermin dielectric function. The resulting ion potential exhibits an oscillatory structure with attractive minima (wakes) and, thus, strongly deviates from the static Yukawa potential of equilibrium plasmas. This potential is analyzed in detail for high-density plasmas with values of the Brueckner parameter in the range 0.1≤r(s)≤1 for a broad range of plasma temperature and electron streaming velocity. It is shown that wake effects become weaker with increasing temperature of the electrons. Finally, we obtain the minimal electron streaming velocity for which attraction between ions occurs. This velocity turns out to be less than the electron Fermi velocity. Our results allow for reliable predictions of the strength of wake effects in nonequilibrium quantum plasmas with fast streaming electrons showing that these effects are crucial for transport under warm-dense-matter conditions, in particular for laser-matter interaction, electron-ion temperature equilibration, and stopping power.

  11. Latency of auditory evoked potential monitoring the effects of general anesthetics on nerve fibers and synapses

    OpenAIRE

    Bowan Huang; Feixue Liang; Lei Zhong; Minlin Lin; Juan Yang; Linqing Yan; Jinfan Xiao; Zhongju Xiao

    2015-01-01

    Auditory evoked potential (AEP) is an effective index for the effects of general anesthetics. However, it’s unknown if AEP can differentiate the effects of general anesthetics on nerve fibers and synapses. Presently, we investigated AEP latency and amplitude changes to different acoustic intensities during pentobarbital anesthesia. Latency more regularly changed than amplitude during anesthesia. AEP Latency monotonically decreased with acoustic intensity increase (i.e., latency-intensity curv...

  12. The Effectiveness of Positive Coping Program on Reduction of Addiction Potential in Students

    Directory of Open Access Journals (Sweden)

    Fatemeh Nematollahi

    2010-02-01

    Full Text Available Objective: This study aimed to study the effectiveness of positive coping program on reduction of addiction potential in dormitory girl students. Method: The research method was semi experimental method namely: pre test-post test with witness group. In selection of sample, first addiction potential scale administered among 160 dormitory girl students, and 20 of them who were scored higher than cutoff score on addiction potential scale selected and divided to two experimental and witness groups. Experimental group received 10 sessions training which each session was 90 minutes. Positive coping program was based on three components of Bob Murray’s theory namely: social relationships, goal setting and spirituality. After finishing of training Post test were administered in both experimental and witness groups. Results: The results showed positive coping training was significantly reduced students’ addiction potential. Conclusion: The training of positive coping can be affect on reduction of girl students’ addiction potential.

  13. Effect of diffusion potential, osmosis and ion-exchange on transdermal drug delivery: theory and experiments.

    Science.gov (United States)

    Hirvonen, J; Murtomäki, L; Kontturi, K

    1998-12-04

    Equations expressing the effect of the diffusion potential on the trace ion transfer across a porous charged membrane have been derived. These equations have been tested with experiments with human cadaver skin. The transfer of sotalol and salicylate was measured varying the salt (NaCl) concentration in the donor and receiver compartments. It appears that osmotic pressure and ion-exchange make a significant contribution to the flux enhancement by the diffusion potential.

  14. Effect of the dipole potential of a bilayer lipid membrane on gramicidin channel dissociation kinetics.

    OpenAIRE

    Rokitskaya, T I; Antonenko, Y N; Kotova, E A

    1997-01-01

    A technique of measuring of the light-induced transients of the gramicidin-mediated electric current across a membrane in the presence of a photosensitizer has been applied for the study of the effect of agents modifying the dipole potential of a bilayer lipid membrane (phloretin, 6-ketocholestanol, and RH421) on the processes of the gramicidin channel dissociation and formation. It is shown that phloretin, known to lower the dipole potential, decelerates the flash-induced decrease in the cur...

  15. Numerical study of Kondo impurity models with strong potential scattering: - reverse Kondo effect and antiresonance -

    OpenAIRE

    Kiss, Annamaria; Kuramoto, Yoshio; Hoshino, Shintaro

    2011-01-01

    Accurate numerical results are derived for transport properties of Kondo impurity systems with potential scattering and orbital degeneracy. Using the continuous-time quantum Monte Carlo (CT-QMC) method, static and dynamic physical quantities are derived in a wide temperature range across the Kondo temperature T_K. With strong potential scattering, the resistivity tends to decrease with decreasing temperature, in contrast to the ordinary Kondo effect. Correspondingly, the quasi-particle densit...

  16. Piezoelectric and deformation potential effects of strain-dependent luminescence in semiconductor quantum well structures

    DEFF Research Database (Denmark)

    Zhang, Aihua; Peng, Mingzeng; Willatzen, Morten;

    2017-01-01

    , in the framework of the 6 × 6 k·p Hamiltonian for the valence states, to directly assess the interplay between the spin-orbit coupling and the strain-induced deformation potential for the interband momentum-matrix element. We numerically addressed problems of both the infinite and IQWs with piezoelectric fields...... to elucidate the effects of the piezoelectric potential and the deformation potential on the strain-dependent luminescence. The experimentally measured photoluminescence variatio½n as a function of pressure can be qualitatively explained by the theoretical results....

  17. Non-perturbative fixed points and renormalization group improved effective potential

    Directory of Open Access Journals (Sweden)

    A.G. Dias

    2014-12-01

    Full Text Available The stability conditions of a renormalization group improved effective potential have been discussed in the case of scalar QED and QCD with a colorless scalar. We calculate the same potential in these models assuming the existence of non-perturbative fixed points associated with a conformal phase. In the case of scalar QED the barrier of instability found previously is barely displaced as we approach the fixed point, and in the case of QCD with a colorless scalar not only the barrier is changed but the local minimum of the potential is also changed.

  18. Effective potential and off-shell two-body scattering amplitudes in the eikonal approximation

    Energy Technology Data Exchange (ETDEWEB)

    Bartnik, E.A.; Rek, Z.

    1973-12-31

    An effective potential is computed for 2-body elastic scattering with the experimental on-shell t-matrices as an input. Nonrelativistic elkonal approximation and locality together with spherical ial are assumed. The explicit form of potential for pp, pi /sup +/p, and pi /sup -/p in the energy range from 5 to 20 GeV is investigated. The half off-shell scattering amplitude is calculated in the potential model. In the position representation this amplitude is found to be asymmetric along the eikonal direction, and an interesting absorption interpretation of this fact is given. (auth)

  19. Investigating CSI: portrayals of DNA testing on a forensic crime show and their potential effects.

    Science.gov (United States)

    Ley, Barbara L; Jankowski, Natalie; Brewer, Paul R

    2012-01-01

    The popularity of forensic crime shows such as CSI has fueled debate about their potential social impact. This study considers CSI's potential effects on public understandings regarding DNA testing in the context of judicial processes, the policy debates surrounding crime laboratory procedures, and the forensic science profession, as well as an effect not discussed in previous accounts: namely, the show's potential impact on public understandings of DNA and genetics more generally. To develop a theoretical foundation for research on the "CSI effect," it draws on cultivation theory, social cognitive theory, and audience reception studies. It then uses content analysis and textual analysis to illuminate how the show depicts DNA testing. The results demonstrate that CSI tends to depict DNA testing as routine, swift, useful, and reliable and that it echoes broader discourses about genetics. At times, however, the show suggests more complex ways of thinking about DNA testing and genetics.

  20. Effects of Colored Noise on Self-Propelled Particles in a Two-Dimensional Potential

    Science.gov (United States)

    Wang, Bing; Li, Xuechao; Chen, Changzhao; Ma, Jianli

    2016-10-01

    The effects of colored noise on self-propelled particles in a two-dimensional potential are investigated. The resonance phenomenon was found as the the average velocity has a maximum value with increasing x direction noise intensity. The average velocity takes its maximal value as the parameters (the y direction noise intensity, the self-propelled angle noise intensity, and so on) take suitable values. The y direction noise and the self-propelled angle noise have great effects on the x direction particles transport. The y direction noise and the self-propelled angle noise cannot induce x direction particles transport in the absence of x direction noise. The ratchet effect should disappear when there is no coupling between the x direction potential and the y direction potential.

  1. Naloxone potentiates the disruptive effects of mescaline on operant responding in the rat.

    Science.gov (United States)

    Commissaris, R L; Moore, K E; Rech, R H

    1980-10-01

    Food-deprived male rats were trained to press a lever on a fixed ratio-40 (FR-40) operant schedule for food reinforcement. Administration of mescaline (4.0--10.0 mg/kg) immediately before the start of the operant session resulted in a cessation of responding for some portion of the 40-min period ("hallucinatory pause"). The duration of this pause was found to be dose-dependent. Although administration of naloxone alone (1.0-8.0 mg/kg, five minutes prior to the start of the session) had no effect on FR-40 responding per se, pretreatment with this agent significantly potentiated the disruptive effects of mescaline. This potentiation by naloxone was further shown to be dose-dependent. These data suggest that the effects of the phenethylamine hallucinogen mescaline are potentiated by pretreatment with the narcotic antagonist naloxone.

  2. Potential Research on Holographic Schwinger Effect with Rotating Probe D3-brane etc

    CERN Document Server

    Xu, Hao

    2016-01-01

    This paper presents the potential research on holographic Schwinger effect with rotating probe D3-brane etc. We discover, for zero temperature case in the Schwinger effect, the faster the angular velocity, the farther the distance of the test particles pair at D3-brane, the potential barrier of total potential energy also grows higher and wider. This paper discovers: at finite temperature, when S5 without rotation near the horizon, there is the failure of the Schwinger effect because the particles will remain at annihilate state, which is an absolute vacuum state. However, the angular velocity in S5 will avoid the existence of the absolute vacuum near the horizon. Both zero and finite temperature states, the achieved results completely agree with the results of the DBI action. So the theories of this paper are consistent, all these show that these theories will play important roles in pair production research in the future.

  3. Evaluation of soil temperature effect on herbicide leaching potential into groundwater in the Brazilian Cerrado.

    Science.gov (United States)

    Paraíba, Lourival Costa; Cerdeira, Antonio Luiz; da Silva, Enio Fraga; Martins, João Souza; Coutinho, Heitor Luiz da Costa

    2003-12-01

    The effect of annual variations in the daily average soil temperatures, at different depths, on the calculation of pesticide leaching potential indices is presented. This index can be applied to assess the risk of groundwater contamination by a pesticide. It considers the effects of water table depth, daily recharge net rate, pesticide sorption coefficient, and degradation rate of the pesticide in the soil. The leaching potential index is frequently used as a screening indicator in pesticide groundwater contamination studies, and the temperature effect involved in its calculation is usually not considered. It is well known that soil temperature affects pesticide degradation rates, air-water partition coefficient, and water-soil partition coefficient. These three parameters are components of the attenuation and retardation factors, as well as the leaching potential index, and contribute to determine pesticide behavior in the environment. The Arrhenius, van't Hoff, and Clausius-Clapeyron equations were used in this work to estimate the soil temperature effect on pesticide degradation rate, air-water partition coefficient, and water-soil partition coefficient, respectively. The relationship between leaching potential index and soil temperature at different depths is presented and aids in the understanding of how potential pesticide groundwater contamination varies on different climatic conditions. Numerical results will be presented for 31 herbicides known to be used in corn and soybean crops grown on the municipality of São Gabriel do Oeste, Mato Grosso do Sul State, Brazil.

  4. Pharmacodynamic Modelling of Placebo and Buprenorphine Effects on Event-Related Potentials in Experimental Pain

    DEFF Research Database (Denmark)

    Juul, Rasmus V; Foster, David J R; Upton, Richard N

    2014-01-01

    The purpose of the study was to investigate placebo and buprenorphine effects on event-related potentials (ERPs) in experimental pain and the potential benefit of population pharmacodynamic modelling in data analysis. Nineteen healthy volunteers received transdermal placebo and buprenorphine...... in a cross-over study. Drug plasma concentrations and ERPs after electrical stimulation at the median nerve with intensity adjusted to pain detection threshold were recorded until 144 hrs after administration. Placebo and concentration-effect models were fitted to data using non-linear mixed......-effects modelling implemented in NONMEM (V7.2.0.). Pharmacodynamic models were developed to adequately describe both placebo and buprenorphine ERP data. Models predicted significant placebo effects, but did not predict significant effects related to buprenorphine concentration. Models revealed that ERPs varied both...

  5. Naloxone potentiates the inotropic effects of isoproterenol in vitro by a nonopiate receptor mechanism.

    Science.gov (United States)

    Lechner, R B

    1992-11-01

    Naloxone potentiates the effects of adrenergic agonists when administered to hypovolemic dogs, and it has been assumed that this effect is due to naloxone's action at opiate receptors. To help determine the site and mechanism of this interaction, we administered naloxone and its "d" stereo-isomer (which does not bind to opiate receptors) to guinea pig papillary muscles in the presence and absence of pharmacologic (isoproterenol) and physiologic (treppe) inotropic stimulation. In control muscles and in rapidly paced muscles, naloxone was without significant inotropic effect. In the presence of isoproterenol, d- and l-naloxone exerted significant positive inotropic effects that were dose dependent. We conclude that, since both d- and l-naloxone potentiated the inotropic effects of isoproterenol and this was seen in the absence of opioids, naloxone may increase contractility by a nonopiate receptor-mediated mechanism.

  6. Effects of some heavy metals on the action potentials of an identified Helix pomatia photosensitive neuron.

    Science.gov (United States)

    Kartelija, Gordana; Radenović, Lidija; Todorović, Natasa; Nedeljković, Miodrag

    2005-06-01

    In the photosensitive MB neuron in the left parietal ganglion of Helix pomatia, the onset of light prolongs significantly (by about 40%) the duration of the action potential. The broadening of the action potential after the onset of light was found to be due to its calcium component and could not be induced after blocking Ca(2+) channels by Cd(2+) and Pb(2+) and in absence of Ca(2+) in medium. The blocking effect of both compounds was reversible. It was found that CdCl(2) exhibited a more intense blocking effect than PbCl(2).

  7. Scalar O(N) Model at Finite Temperature -- 2PI Effective Potential in Different Approximations

    CERN Document Server

    Baacke, J; Baacke, Jurgen; Michalski, Stefan

    2004-01-01

    We calculate the two-particle irreducible (2PI) effective potential of the O(N) linear sigma model in 1+1 dimensions. The approximations we use are the next-to-leading order of a 1/N expansion (for arbitrary N) and a kind of "resummed loop approximation" for N=1. We show that the effective potential of the 1/N expansion is convex for N=4 and N=10 whereas it is not for the "loop" expansion and the case N=1 of the 1/N expansion.

  8. All one-loop scalar vertices in the effective potential approach

    Science.gov (United States)

    Camargo-Molina, José Eliel; Morais, António P.; Pasechnik, Roman; Sampaio, Marco O. P.; Wessén, Jonas

    2016-08-01

    Using the one-loop Coleman-Weinberg effective potential, we derive a general analytic expression for all the derivatives of the effective potential with respect to any number of classical scalar fields. The result is valid for a renormalisable theory in four dimensions with any number of scalars, fermions or gauge bosons. This result corresponds to the zero-external momentum contribution to a general one-loop diagram with N scalar external legs. We illustrate the use of the general result in two simple scalar singlet extensions of the Standard Model, to obtain the dominant contributions to the triple couplings of light scalar particles under the zero external momentum approximation.

  9. Effect of pair potential anisotropy on the electric charge transport in superconducting junctions

    Energy Technology Data Exchange (ETDEWEB)

    Herrera, W.; Nino, V. [Universidad Nacional de Colombia, Bogota (Colombia). Dept. de Fisica

    2000-07-01

    Through the solutions of the Bogoliubov-de Gennes equations we investigate the effect of the anisotropy of the pair potential on the differential conductance of N-S-I-N (N: normal metal, S: superconductor, I: insulator) junctions. We find oscillations in the conductance which in the isotropic case coincide with the Tomasch effect. The influence of different pair potential symmetries on the transport properties is analyzed in detail. In particular, different s-symmetries (isotropic, anisotropic, extended) and d-symmetries are considered. (orig.)

  10. Potentiated cytotoxic effects of statins and ajoene in murine melanoma cells.

    Science.gov (United States)

    Ledezma, Eliades; Wittig, Olga; Alonso, Jose; Cardier, Jose E

    2009-04-01

    Because statins and ajoene inhibit the 3-hydroxy-3-methyl-glutaryl coenzyme A reductase, we evaluated the hypothesis that the cytotoxic effect of these compounds may be potentiated when both are used in combination on tumor cells. We showed that cotreatment of the murine melanoma B16F10 cell with statins (atorvastatin and pravastatin) and ajoene, all at nontoxic doses, dramatically increased their cytotoxicity. B16F10 cell death induced by statins, but not by ajoene, was prevented by mevalonate and geranylgeranylpyrophosphate. To our knowledge, this is the first report that the combination of statins and ajoene, which alters the mevalonate pathway, might potentiate their cytotoxic effects on tumor cells.

  11. The effect of added enzymes on process potentials derived from different qualities of barley

    DEFF Research Database (Denmark)

    Shetty, Radhakrishna; Zhuang, Shiwen; Hansen, Preben Bøje;

    Barley sorting is an important step for picking up grain of desired quality. Whilst brewing with 100% sorted barley (picked high quality) has become realistic with the addition of exogenous enzymes, the effect of added enzymes on process potentials derived from un-sorted barley (mixed) and sorted...... filterability, the Ondea® Pro treatment resulted in significantly lower turbidity and smaller particle size compared to Cellic® CTec2; however, this effect was observed in sorted and un-sorted barley but not in sorted-out barley. Consequently the un-sorted barley demonstrated great potential in brewing process...

  12. Potential health effects of exposure to carcinogenic compounds in incense smoke in temple workers.

    Science.gov (United States)

    Navasumrit, Panida; Arayasiri, Manasawee; Hiang, Ohmar May Tin; Leechawengwongs, Manoon; Promvijit, Jeerawan; Choonvisase, Suppachai; Chantchaemsai, Samroeng; Nakngam, Netnapa; Mahidol, Chulabhorn; Ruchirawat, Mathuros

    2008-05-09

    Incense smoke is a potential hazard to human health due to various airborne carcinogens emitted from incense burning. This study aimed to evaluate the potential health effects of exposure to benzene, 1,3-butadiene, and polycyclic aromatic hydrocarbons (PAHs) emitted from incense smoke in temple workers. Exposure and health risks were assessed through the measurement of ambient exposure as well as through the use of biomarkers of exposure and early biological effects. Ambient air measurement showed that incense burning generates significantly higher levels of airborne benzene (Pincense burning may increase health risk for the development of cancer in temple workers.

  13. All one-loop scalar vertices in the effective potential approach

    CERN Document Server

    Camargo-Molina, José Eliel; Pasechnik, Roman; Sampaio, Marco O P; Wessén, Jonas

    2016-01-01

    Using the one-loop Coleman-Weinberg effective potential, we derive a general analytic expression for all the derivatives of the effective potential with respect to any number of classical scalar fields. The result is valid for a renormalisable theory in four dimensions with any number of scalars, fermions or gauge bosons. This result corresponds to the zero-external momentum contribution to a general one-loop diagram with N scalar external legs. We illustrate the use of the general result in two simple scalar singlet extensions of the Standard Model, to obtain the dominant contributions to the triple couplings of light scalar particles under the zero external momentum approximation

  14. Three-loop Standard Model effective potential at leading order in strong and top Yukawa couplings

    Energy Technology Data Exchange (ETDEWEB)

    Martin, Stephen P. [Santa Barbara, KITP

    2014-01-08

    I find the three-loop contribution to the effective potential for the Standard Model Higgs field, in the approximation that the strong and top Yukawa couplings are large compared to all other couplings, using dimensional regularization with modified minimal subtraction. Checks follow from gauge invariance and renormalization group invariance. I also briefly comment on the special problems posed by Goldstone boson contributions to the effective potential, and on the numerical impact of the result on the relations between the Higgs vacuum expectation value, mass, and self-interaction coupling.

  15. Effects of acetylcholine and noradrenalin on action potentials of isolated rabbit sinoatrial and atrial myocytes

    Directory of Open Access Journals (Sweden)

    Arie O. Verkerk

    2012-05-01

    Full Text Available The autonomic nervous system controls heart rate and contractility through sympathetic and parasympathetic inputs to the cardiac tissue, with acetylcholine (ACh and noradrenalin (NA as the chemical transmitters. In recent years, it has become clear that specific Regulators of G protein Signalling proteins (RGS proteins suppress muscarinic sensitivity and parasympathetic tone, identifying RGS proteins as intriguing potential therapeutic targets. In the present study, we have identified the effects of 1 µM ACh and 1 µM NA on the intrinsic action potentials of sinotrial (SA nodal and atrial myocytes. Single cells were enzymatically isolated from the SA node or from the left atrium of rabbit hearts. Action potentials were recorded using the amphotericin-perforated patch-clamp technique in the absence and presence of ACh, NA or a combination of both. In SA nodal myocytes, ACh increased cycle length and decreased diastolic depolarization rate, whereas NA decreased cycle length and increased diastolic depolarization rate. Both ACh and NA increased maximum upstroke velocity. Furthermore, ACh hyperpolarized the maximum diastolic potential. In atrial myocytes stimulated at 2 Hz, both ACh and NA hyperpolarized the maximum diastolic potential, increased the action potential amplitude, and increased the maximum upstroke velocity. Action potential duration at 50 and 90% repolarization was decreased by ACh, but increased by NA. The effects of both ACh and NA on action potential duration showed a dose dependence in the range of 1–1,000 nM, while a clear-cut frequency dependence in the range of 1–4 Hz was absent. Intermediate results were obtained in the combined presence of ACh and NA in both SA nodal and atrial myocytes. Our data uncover the extent to which SA nodal and atrial action potentials are intrinsically dependent on ACh, NA or a combination of both and may thus guide further experiments with RGS proteins.

  16. Effects of nicotine on visuo-spatial selective attention as indexed by event-related potentials.

    Science.gov (United States)

    Meinke, A; Thiel, C M; Fink, G R

    2006-08-11

    Nicotine has been shown to specifically reduce reaction times to invalidly cued targets in spatial cueing paradigms. In two experiments, we used event-related potentials to test whether the facilitative effect of nicotine upon the detection of invalidly cued targets is due to a modulation of perceptual processing, as indexed by early attention-related event-related potential components. Furthermore, we assessed whether the effect of nicotine on such unattended stimuli depends upon the use of exogenous or endogenous cues. In both experiments, the electroencephalogram was recorded while non-smokers completed discrimination tasks in Posner-type paradigms after chewing a nicotine polacrilex gum (Nicorette 2 mg) in one session and a placebo gum in another session. Nicotine reduced reaction times to invalidly cued targets when cueing was endogenous. In contrast, no differential effect of nicotine on reaction times was observed when exogenous cues were used. Electrophysiologically, we found a similar attentional modulation of the P1 and N1 components under placebo and nicotine but a differential modulation of later event-related potential components at a frontocentral site. The lack of a drug-dependent modulation of P1 and N1 in the presence of a behavioral effect suggests that the effect of nicotine in endogenous visuo-spatial cueing tasks is not due to an alteration of perceptual processes. Rather, the differential modulation of frontocentral event-related potentials suggests that nicotine acts at later stages of target processing.

  17. Effect of an educational game on university students' learning about action potentials.

    Science.gov (United States)

    Luchi, Kelly Cristina Gaviao; Montrezor, Luís Henrique; Marcondes, Fernanda K

    2017-06-01

    The aim of this study was to evaluate the effect of an educational game that is used for teaching the mechanisms of the action potentials in cell membranes. The game was composed of pieces representing the intracellular and extracellular environments, ions, ion channels, and the Na(+)-K(+)-ATPase pump. During the game activity, the students arranged the pieces to demonstrate how the ions move through the membrane in a resting state and during an action potential, linking the ion movement with a graph of the action potential. To test the effect of the game activity on student understanding, first-year dental students were given the game to play at different times in a series of classes teaching resting membrane potential and action potentials. In all experiments, students who played the game performed better in assessments. According to 98% of the students, the game supported the learning process. The data confirm the students' perception, indicating that the educational game improved their understanding about action potentials.

  18. Alternative derivation of an exchange-only density-functional optimized effective potential

    Science.gov (United States)

    Joubert, D. P.

    2007-10-01

    An alternative derivation of the exchange-only density-functional optimized effective potential equation is given. It is shown that the localized Hartree-Fock common energy denominator Green’s function approximation (LHF-CEDA) for the density-functional exchange potential proposed independently by Della Sala and Görling [J. Chem. Phys. 115, 5718 (2001)] and Gritsenko and Baerends [Phys. Rev. A 64, 42506 (2001)] can be derived as an approximation to the OEP exchange potential in a similar way that the KLI approximation [Phys. Rev. A 45, 5453 (1992)] was derived. An exact expression for the correction term to the LHF-CEDA approximation can thus be found. The correction term can be expressed in terms of the first-order perturbation-theory many-electron wave function shift when the Kohn-Sham Hamiltonian is subjected to a perturbation equal to the difference between the density-functional exchange potential and the Hartree-Fock nonlocal potential, expressed in terms of the Kohn-Sham orbitals. An explicit calculation shows that the density weighted mean of the correction term is zero, confirming that the LHF-CEDA approximation can be interpreted as a mean-field approximation. The corrected LHF-CEDA equation and the optimized effective potential equation are shown to be identical, with information distributed differently between terms in the equations. For a finite system the correction term falls off at least as fast as 1/r4 for large r .

  19. The effect of alcohol on cervical and ocular vestibular evoked myogenic potentials in healthy volunteers

    OpenAIRE

    Rosengren, S M; Weber, K P; Hegemann, S C A; Roth, T N

    2014-01-01

    OBJECTIVE: We investigated the effect of alcohol on the cervical and ocular vestibular evoked myogenic potentials (cVEMPs and oVEMPs). As alcohol produces gaze-evoked nystagmus (GEN), we also tested the effect of nystagmus independent of alcohol by recording oVEMPs during optokinetic stimulation (OKS). METHODS: The effect of alcohol was tested in 14 subjects over multiple rounds of alcohol consumption up to a maximum breath alcohol concentration (BrAC) of 1.5‰ (mean 0.97‰). The effect of O...

  20. Effects of attractiveness on face memory separated from distinctiveness: evidence from event-related brain potentials.

    Science.gov (United States)

    Wiese, Holger; Altmann, Carolin S; Schweinberger, Stefan R

    2014-04-01

    The present study examined effects of attractiveness on behavioral and event-related potential (ERP) correlates of face memory. Extending previous reports, we controlled for potential moderating effects of distinctiveness, a variable known to affect memory. Attractive and unattractive faces were selected on the basis of a rating study, and were matched for distinctiveness. In a subsequent recognition memory experiment, we found more accurate memory for unattractive relative to attractive faces. Additionally, an attractiveness effect in the early posterior negativity (EPN) during learning, with larger amplitudes for attractive than unattractive faces, correlated significantly with the magnitude of the memory advantage for unattractive faces at test. These findings establish a contribution of attractiveness to face memory over and above the well-known effect of distinctiveness. Additionally, as the EPN is typically enhanced for affective stimuli, our ERP results imply that the processing of emotionally relevant attractive faces during learning may hamper their encoding into memory. Copyright © 2014 Elsevier Ltd. All rights reserved.